Wang, Wangchen; Yang, Lin; Huang, Huey W.
2007-01-01
Recent experiments suggested that cholesterol and other lipid components of high negative spontaneous curvature facilitate membrane fusion. This is taken as evidence supporting the stalk-pore model of membrane fusion in which the lipid bilayers go through intermediate structures of high curvature. How do the high-curvature lipid components lower the free energy of the curved structure? Do the high-curvature lipid components modify the average spontaneous curvature of the relevant monolayer, thereby facilitate its bending, or do the lipid components redistribute in the curved structure so as to lower the free energy? This question is fundamental to the curvature elastic energy for lipid mixtures. Here we investigate the lipid distribution in a monolayer of a binary lipid mixture before and after bending, or more precisely in the lamellar, hexagonal, and distorted hexagonal phases. The lipid mixture is composed of 2:1 ratio of brominated di18:0PC and cholesterol. Using a newly developed procedure for the multiwavelength anomalous diffraction method, we are able to isolate the bromine distribution and reconstruct the electron density distribution of the lipid mixture in the three phases. We found that the lipid distribution is homogenous and uniform in the lamellar and hexagonal phases. But in the distorted hexagonal phase, the lipid monolayer has nonuniform curvature, and cholesterol almost entirely concentrates in the high curvature region. This finding demonstrates that the association energies between lipid molecules vary with the curvature of membrane. Thus, lipid components in a mixture may redistribute under conditions of nonuniform curvature, such as in the stalk structure. In such cases, the spontaneous curvature depends on the local lipid composition and the free energy minimum is determined by lipid distribution as well as curvature. PMID:17259270
Novel imaging system for measuring microscale curvatures at high temperatures
NASA Astrophysics Data System (ADS)
Tada, Haruna; Kumpel, Amy E.; Lathrop, Richard E.; Slanina, John B.; Nieva, Patricia; Zavracky, Paul; Miaoulis, Ioannis N.; Wong, Peter Y.
2000-01-01
An innovative system was designed to optically measure the curvature of microelectromechanical system at high temperatures. The system takes advantage of the limited numerical aperture of the imaging system to detect the curvature of cantilever beams. Images of the beam are used to determine beam curvature at high temperatures of up to 850 °C by analyzing the apparent change in beam length as seen by the camera during an experimental trial. The system is designed to operate at very high temperatures, which is difficult in conventional microscale curvature measurement techniques such as scanning electron microscopy or stylus profilometry due to excess heating of peripheral equipment. The system can measure curvatures as small as 300 m-1, which corresponds to tip deflections of 1.5 μm for a 100 μm beam. The resolution of the system is limited by the image resolution of the charge-coupled device camera, and increases at large curvatures. The maximum curvature that can be measured by the system is limited by the increase in system resolution, and is estimated to be 4500 m-1, corresponding to 22 μm deflection for a 100 μm beam. The apparatus was demonstrated to measure the thermally induced curvature of multilayered thin-film cantilever beams. The beams bend at high temperatures due to mismatch in thermal expansion coefficients between the layers. One innovative application of such curvature measurement is the determination of thermophysical properties of thin films at elevated temperatures. This article presents the experimental setup and operational theory of apparatus, as well as curvature measurements obtained by the system. The thermal expansion coefficient of polycrystalline silicon, determined from the curvature measurements, are also discussed.
Conservation of DNA curvature signals in regulatory regions of prokaryotic genes
Jáuregui, Ruy; Abreu-Goodger, Cei; Moreno-Hagelsieb, Gabriel; Collado-Vides, Julio; Merino, Enrique
2003-01-01
DNA curvature plays a well-characterized role in many transcriptional regulation mechanisms. We present evidence for the conservation of curvature signals in putative regulatory regions of several archaeal and eubacterial genomes. Genes with highly curved upstream regions were identified in orthologous groups, based on the annotations of the Cluster of Orthologous Groups of proteins (COG) database. COGs possessing a significant number of genes with curvature signals were analyzed, and conserved properties were found in several cases. Curvature signals related to regulatory sites, previously described in single organisms, were located in a broad spectrum of bacterial genomes. Global regulatory proteins, such as HU, IHF and FIS, known to bind to curved DNA and to be autoregulated, were found to present conserved DNA curvature signals in their regulatory regions, emphasizing the fact that structural parameters of the DNA molecule are conserved elements in the process of transcriptional regulation of some systems. It is currently an open question whether these diverse systems are part of an integrated global regulatory response in different microorganisms. PMID:14627810
Curvature in Arabidopsis inflorescence stems is limited to the region of amyloplast displacement
NASA Technical Reports Server (NTRS)
Weise, S. E.; Kuznetsov, O. A.; Hasenstein, K. H.; Kiss, J. Z.
2000-01-01
Gravitropic sensing in stems and stem-like organs is hypothesized to occur in the endodermis. However, since the endodermis runs the entire length of the stem, the precise site of gravisensing has been difficult to define. In this investigation of gravisensitivity in inflorescence stems of Arabidopsis, we positioned stems in a high gradient magnetic field (HGMF) on a rotating clinostat. Approximately 40% of the young, wild-type (WT) inflorescences, for all positions tested, curved toward the HGMF in the vicinity of the stem exposed to the field. In contrast, when the wedge was placed in the basal region of older inflorescence stems, no curvature was observed. As a control, the HGMF was applied to a starchless mutant, and 5% of the stems curved toward the field. Microscopy of the endodermis in the WT showed amyloplast displacement in the vicinity of the HGMF. Additional structural studies demonstrated that the basal region of WT stems experienced amyloplast displacement and, therefore, suggest this region is capable of gravity perception. However, increased lignification likely prevented curvature in the basal region. The lack of apical curvature after basal amyloplast displacement indicates that gravity perception in the base is not transmitted to the apex. Thus, these results provide evidence that the signal (and thus, response) resulting from perception in Arabidopsis inflorescence stems is spatially restricted.
Plan curvature and landslide probability in regions dominated by earth flows and earth slides
Ohlmacher, G.C.
2007-01-01
Damaging landslides in the Appalachian Plateau and scattered regions within the Midcontinent of North America highlight the need for landslide-hazard mapping and a better understanding of the geomorphic development of landslide terrains. The Plateau and Midcontinent have the necessary ingredients for landslides including sufficient relief, steep slope gradients, Pennsylvanian and Permian cyclothems that weather into fine-grained soils containing considerable clay, and adequate precipitation. One commonly used parameter in landslide-hazard analysis that is in need of further investigation is plan curvature. Plan curvature is the curvature of the hillside in a horizontal plane or the curvature of the contours on a topographic map. Hillsides can be subdivided into regions of concave outward plan curvature called hollows, convex outward plan curvature called noses, and straight contours called planar regions. Statistical analysis of plan-curvature and landslide datasets indicate that hillsides with planar plan curvature have the highest probability for landslides in regions dominated by earth flows and earth slides in clayey soils (CH and CL). The probability of landslides decreases as the hillsides become more concave or convex. Hollows have a slightly higher probability for landslides than noses. In hollows landslide material converges into the narrow region at the base of the slope. The convergence combined with the cohesive nature of fine-grained soils creates a buttressing effect that slows soil movement and increases the stability of the hillside within the hollow. Statistical approaches that attempt to determine landslide hazard need to account for the complex relationship between plan curvature, type of landslide, and landslide susceptibility. ?? 2007 Elsevier B.V. All rights reserved.
NASA Astrophysics Data System (ADS)
Zhang, Y. C.; Shen, C.; Marchaudon, A.; Rong, Z. J.; Lavraud, B.; Fazakerley, A.; Yao, Z.; Mihaljcic, B.; Ji, Y.; Ma, Y. H.; Liu, Z. X.
2016-05-01
Theory predicts that the first adiabatic invariant of a charged particle may be violated in a region of highly curved field lines, leading to significant pitch angle scattering for particles whose gyroradius are comparable to the radius of the magnetic field line curvature. This scattering generates more isotropic particle distribution functions, with important impacts on the presence or absence of plasma instabilities. Using magnetic curvature analysis based on multipoint Cluster spacecraft observations, we present the first investigation of magnetic curvature in the vicinity of an ion diffusion region where reconnected field lines are highly curved. Electrons at energies > 8 keV show a clear pitch angle ordering between bidirectional and trapped distribution in surrounding regions, while we show that in the more central part of the ion diffusion region electrons above such energies become isotropic. By contrast, colder electrons (~1 keV) retain their bidirectional character throughout the diffusion regions. The calculated adiabatic parameter K2 for these electrons is in agreement with theory. This study provides the first observational evidence for particle pitch angle scattering due to magnetic field lines with well characterized curvature in a space plasma.
Scattering Theory Calculations of Casimir Energies at High Curvature
NASA Astrophysics Data System (ADS)
Graham, Noah; Emig, Thorsten; Forrow, Aden; Jaffe, Robert; Kardar, Mehran; Maghrebi, Mohammad; Rahi, Jamal; Shpunt, Alex
2013-03-01
Scattering theory provides a powerful tool for capturing the response of an object to electromagnetic charge and field fluctuations. Techniques based on scattering theory have made possible a wide range of new calculations of Casimir energies. In this approach, the Casimir interaction energy for a collection of objects can be expressed in terms of the scattering T-matrices for each object individually, combined with universal translation matrices describing the objects' relative positions and orientations. These translation matrices are derived from an expansion of the free Green's function in an appropriate coordinate system, independent of the details of the objects themselves. This method proves particularly valuable for geometries involving high curvature, such as edges and tips. I will describe this approach in general terms and then give results from several problems to which it has been applied successfully. I will also discuss new developments in scattering theory that have been motivated by these problems. I would like to request that this abstract be part of a session on Casimir physics. Supported by the National Science Foundation, the US Department of Energy, the Defense Advanced Research Projects Agency, and the Deutsche Forschungsgemeinschaft
3D Hole Inspection Using Lens with High Field Curvature
NASA Astrophysics Data System (ADS)
Zavyalov, Petr
2015-02-01
One of the actual 3D measurement problems is the optical inspection of various holes. In this respect, the task of plane image formation of holes as extended 3D objects using optical methods turns out to be of primary importance. We have developed specialized lenses that perform such transformations due to specially increased aberrations (field curvature, astigmatism) for the formation of extended objects plane images. The calculations of the lens parameters are presented. The detail analysis of the imaging properties was carried out. The presented hole inspection lens has been designed, constructed and used for inspection of the fuel assembly spacer grids.
A high-sensitive fiber curvature sensor using twin core fiber-based filter
NASA Astrophysics Data System (ADS)
Yin, G. L.; Lou, S. Q.; Lu, W. L.; Wang, X.
2014-04-01
A high-sensitive fiber curvature sensor is proposed and experimentally demonstrated in a large measurement range by using a twin core fiber (TCF)-based filter as sensor head. Applying the coupled-mode theory and equivalent refractive index model, we theoretically anticipate the "blue shift" of the transmission dips of the TCF-based filter when sensor head is bent. Experimentally, we fabricate an 86.9 mm TCF-based filter with a free spectral range of 49 nm and characterize its curvature performance by measuring the wavelength shift. A nonlinear "blue shift" of the wavelength is observed when we increase the curvature. The relationship between wavelength shift and curvature is a second-order polynomial function. In the range from 0 to 9.30 m-1, the maximum sensitivity is up to -14.7 nm/m-1. The measurement range can be further increased by selecting a shorter TCF.
Classification and quantification of leaf curvature
Liu, Zhongyuan; Jia, Liguo; Mao, Yanfei; He, Yuke
2010-01-01
Various mutants of Arabidopsis thaliana deficient in polarity, cell division, and auxin response are characterized by certain types of leaf curvature. However, comparison of curvature for clarification of gene function can be difficult without a quantitative measurement of curvature. Here, a novel method for classification and quantification of leaf curvature is reported. Twenty-two mutant alleles from Arabidopsis mutants and transgenic lines deficient in leaf flatness were selected. The mutants were classified according to the direction, axis, position, and extent of leaf curvature. Based on a global measure of whole leaves and a local measure of four regions in the leaves, the curvature index (CI) was proposed to quantify the leaf curvature. The CI values accounted for the direction, axis, position, and extent of leaf curvature in all of the Arabidopsis mutants grown in growth chambers. Comparison of CI values between mutants reveals the spatial and temporal variations of leaf curvature, indicating the strength of the mutant alleles and the activities of the corresponding genes. Using the curvature indices, the extent of curvature in a complicated genetic background becomes quantitative and comparable, thus providing a useful tool for defining the genetic components of leaf development and to breed new varieties with leaf curvature desirable for the efficient capture of sunlight for photosynthesis and high yields. PMID:20400533
Radiotherapy margin design with particular consideration of high curvature CTVs
Herschtal, Alan; Kron, Tomas; Fox, Chris
2009-03-15
In applying 3D conformal radiation therapy to a tumor clinical target volume (CTV), a margin is added around the CTV to account for any sources of error in the application of treatment which may result in misalignment between the CTV and the dose distribution actually delivered. The volume enclosed within the CTV plus the margin is known as the PTV, or planning target volume. The larger the errors are anticipated to be, the wider the margin will need to be to accommodate those errors. Based on the approach of van Herk et al. [''The probability of correct target dosage: Dose-population histograms for deriving treatment margins in radiotherapy,'' Int. J. Radiat. Oncol. Biol., Phys. 47(4), 1121-1135 (2000)] this paper develops the mathematical theory behind the calculation of the margin width required to ensure that the entire CTV receives sufficiently high dose with sufficiently high probability. The margin recipe developed not only considers the magnitude of the errors but also includes a term to adjust for curved CTV surfaces. In doing so, the accuracy of the margin recipe is enhanced yet remains mathematically concise enough to be readily implemented in the clinical setting. The results are particularly relevant for clinical situations in which the uncertainties in treatment are large relative to the size of the CTV.
Numerical Analysis of Surface Cracks at Regions of Curvature in Oxide Scales
Williamson, Richard L; Wright, Julie Knibloe; Steffler, Eric Darwin; Cannon, R. M.
2003-02-01
Finite element simulations are used to examine surface cracks at regions of local curvature (corners or convolutions) in protective oxide scales. Stresses are generated during cooling from oxide formation temperatures. Three different modeling approaches are employed, since each adds some insight to crack behavior. For the first, a series of standard static analyses with varying crack lengths is used to approximate crack motion. Next, a simple node-release technique is used, permitting dynamic crack growth along an assumed path. Finally, a model based on an arbitrary crack path is employed, wherein the crack path is included as an unknown and is part of the solution. To quantify geometric effects, three different ratios of corner radii to scale thickness are considered. Further, the influence of the substrate material is investigated by considering both perfectly-plastic and work-hardening behavior. The computed stress-intensity factor at the crack tip is compared to the fracture toughness of the scale material to predict crack growth. Simulations indicate that sharper corners and lower substrate yield strengths increase crack growth potential. Reductions in the stress-intensity factor with increasing crack length are observed that result from the constraining effects of the substrate. Predictions of crack trajectory indicate initial crack motion perpendicular to the free surface of the scale, followed by a near 90° turn, resulting in a crack path nearly parallel to the free surface.
Besnard, Romain; Arrachart, Guilhem; Cambedouzou, Julien; Pellet-Rostaing, Stéphane
2016-05-10
The self-assembly of amino-undecyl-triethoxysilane (AUT) as micelles in water is considered. The behavior of acid/AUT systems is governed by a complete proton transfer from the acid to the amine, leading to the formation of an ammonium headgroup. This moiety is responsible for the bending of the interface between the organic core of the micelles and the surrounding water. By playing with the size of the acid used as curvature agent, the amphiphilic behavior of the organosilane molecule may be adjusted. We follow the aggregation as the curvature agent size increases. This approach constitutes an efficient and original method in order to tune the nanostructure of highly functionalized silica at the early stage of the elaboration. Small-angle X-ray scattering, wet scanning transmission electron microscopy, dynamic light scattering, and complementary characterization techniques indicate that hybrid organic-inorganic planar objects and vesicles are obtained for smaller curvature agents. Increasing the size of the curvature agent results in a transition of the aggregation geometry from vesicles to cylindrical direct micelles, finally leading to nanofibers organized in a 2D hexagonal network resembling a "reverse MCM-41 structure". A geometrical molecular self-assembly model is finally proposed, considering the dimensions of the surfactant tail and those of the head groups. PMID:27081741
New dual-curvature microlens array with a high fill-factor for organic light emitting diode modules
NASA Astrophysics Data System (ADS)
Lin, Tsung-Hung; Yang, Hsiharng; Chao, Ching-Kong; Shui, Hung-Chi
2013-09-01
A new method for fabricating a novel dual-curvature microlens array with a high fill-factor using proximity printing in a lithography process is reported. The lens shapes include dual-curvature, which is a novel shape composed of triangles and hexagons. We utilized UV proximity printing by controlling a printing gap between the mask and substrate. The designed high density microlens array pattern can fabricate a dual-curvature microlens array with a high fill-factor in a photoresist material. It is due to the UV light diffraction which deflects away from the aperture edges and produces a certain exposure in the photoresist material outside the aperture edges. A dual-curvature microlens array with a height ratio of 0.48 can boost axial luminance up to 22%. Therefore, the novel dual-curvature microlens array offers an economical solution for increasing the luminance of organic light emitting diodes.
Gao, Dengliang
2013-03-01
In 3D seismic interpretation, curvature is a popular attribute that depicts the geometry of seismic reflectors and has been widely used to detect faults in the subsurface; however, it provides only part of the solutions to subsurface structure analysis. This study extends the curvature algorithm to a new curvature gradient algorithm, and integrates both algorithms for fracture detection using a 3D seismic test data set over Teapot Dome (Wyoming). In fractured reservoirs at Teapot Dome known to be formed by tectonic folding and faulting, curvature helps define the crestal portion of the reservoirs that is associated with strong seismic amplitude and high oil productivity. In contrast, curvature gradient helps better define the regional northwest-trending and the cross-regional northeast-trending lineaments that are associated with weak seismic amplitude and low oil productivity. In concert with previous reports from image logs, cores, and outcrops, the current study based on an integrated seismic curvature and curvature gradient analysis suggests that curvature might help define areas of enhanced potential to form tensile fractures, whereas curvature gradient might help define zones of enhanced potential to develop shear fractures. In certain fractured reservoirs such as at Teapot Dome where faulting and fault-related folding contribute dominantly to the formation and evolution of fractures, curvature and curvature gradient attributes can be potentially applied to differentiate fracture mode, to predict fracture intensity and orientation, to detect fracture volume and connectivity, and to model fracture networks.
Formation, Stability, and Mobility of One-Dimensional Lipid Bilayer on High Curvature Substrates
Huang, J; Martinez, J; Artyukhin, A; Sirbuly, D; Wang, Y; Ju, J W; Stroeve, P; Noy, A
2007-03-23
Curved lipid membranes are ubiquitous in living systems and play an important role in many biological processes. To understand how curvature and lipid composition affect membrane formation and fluidity we have assembled and studied mixed 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine (DOPC) and 1,2-Dioleoyl-sn-Glycero-3-Phosphoethanolamine (DOPE) supported lipid bilayers on amorphous silicon nanowires with controlled diameters ranging from 20 nm to 200 nm. Addition of cone-shaped DOPE molecules to cylindrical DOPC molecules promotes vesicle fusion and bilayer formation on smaller diameter nanowires. Our experiments demonstrate that nanowire-supported bilayers are mobile, exhibit fast recovery after photobleaching, and have low concentration of defects. Lipid diffusion coefficients in these high-curvature tubular membranes are comparable to the values reported for flat supported bilayers and increase with decreasing nanowire diameter.
Visualization of Secondary Flow Development in High Aspect Ratio Channels with Curvature
NASA Technical Reports Server (NTRS)
Meyer, Michael L.; Giuliani, James E.
1994-01-01
The results of an experimental project to visually examine the secondary flow structure that develops in curved, high aspect-ratio rectangular channels are presented. The results provide insight into the fluid dynamics within high aspect ratio channels. A water flow test rig constructed out of plexiglass, with an adjustable aspect ratio, was used for these experiments. Results were obtained for a channel geometry with a hydraulic diameter of 10.6 mm (0.417 in.), an aspect ratio of 5.0, and a hydraulic radius to curvature radius ratio of 0.0417. Flow conditions were varied to achieve Reynolds numbers up to 5,100. A new particle imaging velocimetry technique was developed which could resolve velocity information from particles entering and leaving the field of view. Time averaged secondary flow velocity vectors, obtained using this velocimetry technique, are presented for 30 degrees, 60 degrees, and 90 degrees into a 180 degrees bend and at a Reynolds number of 5,100. The secondary flow results suggest the coexistence of both the classical curvature induced vortex pair flow structure and the eddies seen in straight turbulent channel flow.
Jaworski, Piotr; Yu, Fei; Carter, Richard M; Knight, Jonathan C; Shephard, Jonathan D; Hand, Duncan P
2015-04-01
In this paper we present an anti-resonant guiding, low-loss Negative Curvature Fiber (NCF) for the efficient delivery of high energy short (ns) and ultrashort (ps) pulsed laser light in the green spectral region. The fabricated NCF has an attenuation of 0.15 dB/m and 0.18 dB/m at 532 nm and 515 nm respectively, and provided robust transmission of nanosecond and picosecond pulses with energies of 0.57 mJ (10.4 kW peak power) and 30 µJ (5 MW peak power) respectively. It provides single-mode, stable (low bend-sensitivity) output and maintains spectral and temporal properties of the source laser beam. The practical application of fiber-delivered pulses has been demonstrated in precision micro-machining and marking of metals and glass. PMID:25968688
ERIC Educational Resources Information Center
Lim, Ik Soo; Leek, E. Charles
2012-01-01
Previous empirical studies have shown that information along visual contours is known to be concentrated in regions of high magnitude of curvature, and, for closed contours, segments of negative curvature (i.e., concave segments) carry greater perceptual relevance than corresponding regions of positive curvature (i.e., convex segments). Lately,…
Liu, Yan; Li, Yanqiu; Cao, Zhen
2016-06-20
An anamorphic magnification extreme ultraviolet (EUV) lithographic objective could increase the size of the exposure field at a wafer in the orthogonal scanning direction to improve the throughput of the lithographic system. In this paper, we present a curvatures combination method for an anamorphic magnification EUV lithographic objective with high numerical aperture (NA). This method achieves an anamorphic magnification initial structure by use of the double-curvature surfaces, which are formed by combining the curvatures of the corresponding surfaces into two coaxial spherical systems. A series of control measures is taken to design the two coaxial spherical systems for ensuring the rationalities of the initial structure and the surfaces after combining. The image quality of the anamorphic initial structure is optimized by a gradual optimization process. Finally, as an example, we design an Mx1/4 and My1/8 anamorphic magnification EUV lithographic objective with the presented design method. This objective achieves 0.5 NA and a 26 mm×16.5 mm exposure field at the wafer. The wavefront error RMS reaches 0.06λ (λ=13.5 nm), and the distortion is less than 2.8 nm. The design result proves the availability of the curvatures combination method. PMID:27409118
Aligning and measuring the curvature and thickness of high-precision lens
NASA Astrophysics Data System (ADS)
Wu, Kun-Huan; Chang, Shenq-Tsong; Hsu, Ming-Ying; Huang, Ting-Ming; Hsu, Wei-Yao; Tseng, Shih-Feng
2015-09-01
The radius of curvature is one of the most important specifications for spherical optics [1]. There are several methods and devices currently on the market that can be used to measure it, including optical level, non-contact laser interferometer (Interferometer), a probe-contact profiler (Profilometer), the centering machine and three-point contact ball diameter meter (Spherometer). The amount that can be measured with a radius of curvature of the lens aperture range depends on the interferometer standard lens f / number and lens of R / number (radius of curvature divided by the clear aperture of the spherical surface ratio between them). Unfortunately, for lens with diameter greater than 300 mm, the device is limited by the size of the holding fixture lenses or space. This paper aims to provide a novel surface contour detection method and machine, named "CMM spherometry by probe compensation," to measure the radius and thickness of the curvature of the optical surface by a coordinate measurement machine (CMM). In order to obtain more accurate optimization results, we used probe and temperature compensation to discuss the effect. The trace samples and the measurement results of CMM and the centering machine, which has top and bottom autocollimators, are compared.
Forman curvature for complex networks
NASA Astrophysics Data System (ADS)
Sreejith, R. P.; Mohanraj, Karthikeyan; Jost, Jürgen; Saucan, Emil; Samal, Areejit
2016-06-01
We adapt Forman’s discretization of Ricci curvature to the case of undirected networks, both weighted and unweighted, and investigate the measure in a variety of model and real-world networks. We find that most nodes and edges in model and real networks have a negative curvature. Furthermore, the distribution of Forman curvature of nodes and edges is narrow in random and small-world networks, while the distribution is broad in scale-free and real-world networks. In most networks, Forman curvature is found to display significant negative correlation with degree and centrality measures. However, Forman curvature is uncorrelated with clustering coefficient in most networks. Importantly, we find that both model and real networks are vulnerable to targeted deletion of nodes with highly negative Forman curvature. Our results suggest that Forman curvature can be employed to gain novel insights on the organization of complex networks.
High-Temperature Characterization of Silicon Dioxide Films with Wafer Curvature
NASA Astrophysics Data System (ADS)
Bigl, S.; Heinz, W.; Kahn, M.; Schoenherr, H.; Cordill, M. J.
2015-12-01
Amorphous silicon dioxide films used as dielectric layers in microelectronic devices are deposited using plasma-enhanced chemical vapor deposition. Because of the presence of hydrogen and nitrogen species in the precursor gases, incorporation of such species in the films can lead to crack formation during subsequent annealing processes up to 1000°C. In this study, the role of film chemistry on the thermo-mechanical behavior of silicon dioxide films is studied with in situ film stress measurements using wafer curvature to maximum temperatures of 1000°C. This is a significant advance because normal wafer curvature can only reach maximum temperatures of around 500°C. The increased temperature range allows for the stress evolution and film chemistry to be examined for the relevant processing conditions. It was found that at temperatures higher than 550°C, hydrogen bond cleavage led to a large stress increase and film chemistry change due to new bonding arrangements between nitrogen and silicon as well as subsequent film densification causing cracking of films. These changes could only be identified with wafer curvature measurements up to 1000°C.
Sugiura, Yuuki; Ikeda, Keisuke; Nakano, Minoru
2015-10-27
Aggregation of the amyloid-β (Aβ) protein and the formation of toxic aggregates are the possible pathogenic pathways in Alzheimer's disease. Accumulating evidence suggests that lipid membranes play key roles in protein aggregation, although the intermolecular forces that drive the interactions between Aβ-(1-40) and the membranes vary in different membrane systems. Here, we observed that a high positive curvature of lipid vesicles with diameters of ∼30 nm enhanced the association of Aβ with anionic phosphatidylglycerol membranes in the liquid-crystalline phase and with zwitterionic phosphatidylcholine membranes in the gel phase. The binding modes of Aβ to these membranes differ in terms of the location of the protein on the membrane and of the protein secondary structure. The fibrillation of Aβ was accelerated in the presence of the vesicles and at high protein-to-lipid ratios. Under these conditions, the protein accumulated on the surfaces, as demonstrated by a high (10(7) M(-1)) binding constant. Our findings suggest that packing defects on membranes with high curvatures, such as the intraluminal vesicles in multivesicular bodies and the exosomes, might result in the accumulation of toxic protein aggregates. PMID:26474149
Curvature Sensing by a Viral Scission Protein.
Martyna, Agnieszka; Gómez-Llobregat, Jordi; Lindén, Martin; Rossman, Jeremy S
2016-06-28
Membrane scission is the final step in all budding processes wherein a membrane neck is sufficiently constricted so as to allow for fission and the release of the budded particle. For influenza viruses, membrane scission is mediated by an amphipathic helix (AH) domain in the viral M2 protein. While it is known that the M2AH alters membrane curvature, it is not known how the protein is localized to the center neck of budding virions where it would be able to cause membrane scission. Here, we use molecular dynamics simulations on buckled lipid bilayers to show that the M2AH senses membrane curvature and preferentially localizes to regions of high membrane curvature, comparable to that seen at the center neck of budding influenza viruses. These results were then validated using in vitro binding assays to show that the M2AH senses membrane curvature by detecting lipid packing defects in the membrane. Our results show that the M2AH senses membrane curvature and suggest that the AH domain may localize the protein at the viral neck where it can then mediate membrane scission and the release of budding viruses. PMID:27299375
Wallace, John Paul; Myneni, Ganapati Rao; Pike, Robert
2011-03-31
The manufacturing of niobium SRF accelerator cavities is plagued by a mobile point defect, hydrogen. For efficient accelerator operation, niobium must function at both high electric and magnetic fields, and is compromised if magnetic impurities are located in the surface regions of the material. The finding that trace hydrogen in niobium can produce structures with magnetic properties is a feature that is not acceptable for a high performance cavity. X-ray diffraction has proved to be the key tool in assessing irreversible process damage to the niobium substrate. In future generations of accelerators, niobium will actually be merely the substrate for more effective superconductors that will allow for more efficient operation. The substrate analogy to the silicon wafer industry is useful since for niobium it may be possible to avoid some of the mistakes made in silicon technology. Because hydrogen attacks niobium on a number of different size scales, there is an inherent complexity in the trouble sources. There are also features in cavity design that are benign, such as local curvature considerations, requiring a fully non symmetric analysis of current flow to be appreciated.
John Paul Wallace, Ganapati Rao Myneni, and Robert Pike
2011-03-01
The manufacturing of niobium SRF accelerator cavities is plagued by a mobile point defect, hydrogen. For efficient accelerator operation, niobium must function at both high electric and magnetic fields, and is compromised if magnetic impurities are located in the surface regions of the material. The finding that trace hydrogen in niobium can produce structures with magnetic properties is a feature that is not acceptable for a high performance cavity. X-ray diffraction has proved to be the key tool in assessing irreversible process damage to the niobium substrate. In future generations of accelerators, niobium will actually be merely the substrate for more effective superconductors that will allow for more efficient operation. The substrate analogy to the silicon wafer industry is useful since for niobium it may be possible to avoid some of the mistakes made in silicon technology. Because hydrogen attacks niobium on a number of different size scales, there is an inherent complexity in the trouble sources. There are also features in cavity design that are benign, such as local curvature considerations, requiring a fully non symmetric analysis of current flow to be appreciated.
On the Weyl curvature hypothesis
NASA Astrophysics Data System (ADS)
Stoica, Ovidiu Cristinel
2013-11-01
The Weyl curvature hypothesis of Penrose attempts to explain the high homogeneity and isotropy, and the very low entropy of the early universe, by conjecturing the vanishing of the Weyl tensor at the Big-Bang singularity.
Nonlinear Development of Goertler Vortices Over Variable Curvature Walls.
NASA Astrophysics Data System (ADS)
Benmalek, Ali
The development of Gortler vortices over walls of variable curvature is studied. This is of interest because of stability and transition studies of boundary layers over surfaces which may have a combination of concave and convex or flat regions such as the lower surface of supercritical low drag suction laminar flow airfoils. The question arises regarding the nature of stabilization of the convex and zero curvature of the wall and whether it is sufficient to overcome the destabilization of the concave region. The parabolized disturbance equations governing the problem for small curvature, high Reynolds number and order one Gortler number are integrated numerically. Cases with concave, convex and zero curvatures are analyzed. The results show significant stabilization of the disturbances in the convex region, where new sets of vortices are successively created with opposite rotation to the preceding set. The "mushroom-shaped" distributions of low-momentum fluid riding above high-momentum fluid that are subject to secondary instability are predicted. The convex curvature tends to eliminate the inflection points from the spanwise and normal profiles of the streamwise velocity and, hence, suppresses the oscillatory secondary instability that leads to turbulence. Stabilization of Gortler vortices in a flat region is found to be less significant than in a convex region. Finally, the question as to whether the Gortler -Witting mechanism is important in boundary-layer transition is addressed.
Coffield, R.D.; Hammond, R.B.; Koczko, J.P.; McKeown, P.T.; Zirpoli, P.J.
1998-06-01
Pressure drops in a piping elbow are experimentally determined for high Reynolds number flows. The testing described has been performed in order to reduce uncertainties in the currently used design values for predicting irrecoverable pressure losses. The earlier high Reynolds number correlations had been based on extrapolations over several orders of magnitude in Reynolds number from where the original database existed. The test data shows about a factor of two lower elbow pressure loss coefficient (at 40 {times} 10{sup 6} Reynolds number) than those current correlations.
NASA Astrophysics Data System (ADS)
Jia, Zhenyuan; Song, Dening; Ma, Jianwei; Gao, Yuanyuan
2016-04-01
Parts with varied curvature features play increasingly critical roles in engineering, and are often machined under high-speed continuous-path running mode to ensure the machining efficiency. However, the continuous-path running trajectory error is significant during high-feed-speed machining, which seriously restricts the machining precision for such parts with varied curvature features. In order to reduce the continuous-path running trajectory error without sacrificing the machining efficiency, a pre-compensation method for the trajectory error is proposed. Based on the formation mechanism of the continuous-path running trajectory error analyzed, this error is estimated in advance by approximating the desired toolpath with spline curves. Then, an iterative error pre-compensation method is presented. By machining with the regenerated toolpath after pre-compensation instead of the uncompensated toolpath, the continuous-path running trajectory error can be effectively decreased without the reduction of the feed speed. To demonstrate the feasibility of the proposed pre-compensation method, a heart curve toolpath that possesses varied curvature features is employed. Experimental results indicate that compared with the uncompensated processing trajectory, the maximum and average machining errors for the pre-compensated processing trajectory are reduced by 67.19% and 82.30%, respectively. An easy to implement solution for high efficiency and high precision machining of the parts with varied curvature features is provided.
Nagaraja, Ashvin T; You, Yil-Hwan; Choi, Jeong-Wan; Hwang, Jin-Ha; Meissner, Kenith E; McShane, Michael J
2016-03-15
The layer-by-layer modification of ≈5 nm mercaptocarboxylic acid stabilized gold nanoparticles was studied in an effort to illustrate effective means to overcome practical issues in handling and performing surface modification of such extremely small materials. To accomplish this, each layer deposition cycle was separated into a multi-step process wherein solution pH was controlled in two distinct phases of polyelectrolyte adsorption and centrifugation. Additionally, a solvent precipitation step was introduced to make processing more amenable by concentrating the sample and exchanging solution pH before ultracentrifugation. The pH-dependent assembly on gold nanoparticles was assessed after each layer deposition cycle by monitoring the plasmon peak absorbance location, surface charge, and the percentage of nanoparticles recovered. The selection of solution pH during the adsorption phase was found to be a critical parameter to enhance particle recovery and maximize surface charge when coating with weak polyelectrolytes. One bilayer was deposited with a high yield and the modified particles exhibited enhanced colloidal stability across a broad pH range and increased ionic strength. These findings support the adoption of this multi-step processing approach as an effective and generalizable approach to improve stability of high surface curvature particles. PMID:26771506
Defining the free-energy landscape of curvature-inducing proteins on membrane bilayers
NASA Astrophysics Data System (ADS)
Tourdot, Richard W.; Ramakrishnan, N.; Radhakrishnan, Ravi
2014-08-01
Curvature-sensing and curvature-remodeling proteins, such as Amphiphysin, Epsin, and Exo70, are known to reshape cell membranes, and this remodeling event is essential for key biophysical processes such as tubulation, exocytosis, and endocytosis. Curvature-inducing proteins can act as curvature sensors; they aggregate to membrane regions matching their intrinsic curvature; as well as induce curvature in cell membranes to stabilize emergent high curvature, nonspherical, structures such as tubules, discs, and caveolae. A definitive understanding of the interplay between protein recruitment and migration, the evolution of membrane curvature, and membrane morphological transitions is emerging but remains incomplete. Here, within a continuum framework and using the machinery of Monte Carlo simulations, we introduce and compare three free-energy methods to delineate the free-energy landscape of curvature-inducing proteins on bilayer membranes. We demonstrate the utility of the Widom test particle (or field) insertion methodology in computing the excess chemical potentials associated with curvature-inducing proteins on the membrane—in particular, we use this method to track the onset of morphological transitions in the membrane at elevated protein densities. We validate this approach by comparing the results from the Widom method with those of thermodynamic integration and Bennett acceptance ratio methods. Furthermore, the predictions from the Widom method have been tested against analytical calculations of the excess chemical potential at infinite dilution. Our results are useful in precisely quantifying the free-energy landscape, and also in determining the phase boundaries associated with curvature-induction, curvature-sensing, and morphological transitions. This approach can be extended to studies exploring the role of thermal fluctuations and other external (control) variables, such as membrane excess area, in shaping curvature-mediated interactions on bilayer
Defining the free-energy landscape of curvature-inducing proteins on membrane bilayers
Tourdot, Richard W.; Ramakrishnan, N.; Radhakrishnan, Ravi
2015-01-01
Curvature-sensing and curvature-remodeling proteins, such as Amphiphysin, Epsin, and Exo70, are known to reshape cell membranes, and this remodeling event is essential for key biophysical processes such as tubulation, exocytosis, and endocytosis. Curvature-inducing proteins can act as curvature sensors; they aggregate to membrane regions matching their intrinsic curvature; as well as induce curvature in cell membranes to stabilize emergent high curvature, nonspherical, structures such as tubules, discs, and caveolae. A definitive understanding of the interplay between protein recruitment and migration, the evolution of membrane curvature, and membrane morphological transitions is emerging but remains incomplete. Here, within a continuum framework and using the machinery of Monte Carlo simulations, we introduce and compare three free-energy methods to delineate the free-energy landscape of curvature-inducing proteins on bilayer membranes. We demonstrate the utility of the Widom test particle (or field) insertion methodology in computing the excess chemical potentials associated with curvature-inducing proteins on the membrane—in particular, we use this method to track the onset of morphological transitions in the membrane at elevated protein densities. We validate this approach by comparing the results from the Widom method with those of thermodynamic integration and Bennett acceptance ratio methods. Furthermore, the predictions from the Widom method have been tested against analytical calculations of the excess chemical potential at infinite dilution. Our results are useful in precisely quantifying the free-energy landscape, and also in determining the phase boundaries associated with curvature-induction, curvature-sensing, and morphological transitions. This approach can be extended to studies exploring the role of thermal fluctuations and other external (control) variables, such as membrane excess area, in shaping curvature-mediated interactions on bilayer
Defining the free-energy landscape of curvature-inducing proteins on membrane bilayers.
Tourdot, Richard W; Ramakrishnan, N; Radhakrishnan, Ravi
2014-08-01
Curvature-sensing and curvature-remodeling proteins, such as Amphiphysin, Epsin, and Exo70, are known to reshape cell membranes, and this remodeling event is essential for key biophysical processes such as tubulation, exocytosis, and endocytosis. Curvature-inducing proteins can act as curvature sensors; they aggregate to membrane regions matching their intrinsic curvature; as well as induce curvature in cell membranes to stabilize emergent high curvature, nonspherical, structures such as tubules, discs, and caveolae. A definitive understanding of the interplay between protein recruitment and migration, the evolution of membrane curvature, and membrane morphological transitions is emerging but remains incomplete. Here, within a continuum framework and using the machinery of Monte Carlo simulations, we introduce and compare three free-energy methods to delineate the free-energy landscape of curvature-inducing proteins on bilayer membranes. We demonstrate the utility of the Widom test particle (or field) insertion methodology in computing the excess chemical potentials associated with curvature-inducing proteins on the membrane-in particular, we use this method to track the onset of morphological transitions in the membrane at elevated protein densities. We validate this approach by comparing the results from the Widom method with those of thermodynamic integration and Bennett acceptance ratio methods. Furthermore, the predictions from the Widom method have been tested against analytical calculations of the excess chemical potential at infinite dilution. Our results are useful in precisely quantifying the free-energy landscape, and also in determining the phase boundaries associated with curvature-induction, curvature-sensing, and morphological transitions. This approach can be extended to studies exploring the role of thermal fluctuations and other external (control) variables, such as membrane excess area, in shaping curvature-mediated interactions on bilayer
Control of curvature in highly compliant probe cantilevers during carbon nanotube growth.
Chen, I-Chen; Chen, Li-Han; Orme, Christine A; Jin, Sungho
2007-10-01
Direct growth of a sharp carbon nanotube (CNT) probe on a very thin and highly flexible cantilever by plasma-enhanced chemical vapor deposition (PECVD) is desirable for atomic force microscopy (AFM) of nanoscale features on soft or fragile materials. Plasma-induced surface stresses in such fabrication processes, however, tend to cause serious bending of these cantilevers, which makes the CNT probe unsuitable for AFM measurements. Here, we report a new tunable CNT growth technique that controls cantilever bending during deposition, thereby enabling the creation of either flat or deliberately curved AFM cantilevers containing a CNT probe. By introducing hydrogen gas to the (acetylene + ammonia) feed gas during CNT growth and adjusting the ammonia to hydrogen flow ratio, the cantilever surface stress can be altered from compressive to tensile stress, and in doing so controlling the degree of cantilever bending. The CNT probes grown under these conditions have high aspect ratios and are robust. Contact-mode imaging has been demonstrated using these probe tips. Such CNT probes can be useful for bio-imaging involving DNA and other delicate biological features in a liquid environment. PMID:17887798
Calculator for conformational statistics of DNA and applications to high-curvature bending
NASA Astrophysics Data System (ADS)
Ross, Brian C.; Wiggins, Paul A.
2013-03-01
DNA conformation plays an important role in a host of cellular processes. Despite the central importance of DNA conformation, there is not yet a general-purpose calculator for conformational statistics that is designed for the scientific community. Here we describe a public tool we developed for calculating an important class of conformational statistics: the end-to-end probability density of finding a locus of the DNA polymer at a given displacement and orientation relative to a second locus on the same polymer. As a demonstration, we propose a cyclization experiment and use our calculator to show that this experiment could measure the energy of DNA bending as a direct function of bend angle in the poorly understood high-bending regime. Our tool is available as both an online calculator and a downloadable program at http://mtshasta.phys.washington.edu/wormulator/.
Impact of Surface Curvature on Dose Delivery in Intraoperative High-Dose-Rate Brachytherapy
Oh, Moonseong Wang Zhou; Malhotra, Harish K.; Jaggernauth, Wainwright; Podgorsak, Matthew B.
2009-04-01
In intraoperative high-dose-rate (IOHDR) brachytherapy, a 2-dimensional (2D) geometry is typically used for treatment planning. The assumption of planar geometry may cause serious errors in dose delivery for target surfaces that are, in reality, curved. A study to evaluate the magnitude of these errors in clinical practice was undertaken. Cylindrical phantoms with 6 radii (range: 1.35-12.5 cm) were used to simulate curved treatment geometries. Treatment plans were developed for various planar geometries and were delivered to the cylindrical phantoms using catheters inserted into Freiburg applicators of varying dimension. Dose distributions were measured using radiographic film. In comparison to the treatment plan (for a planar geometry), the doses delivered to prescription points were higher on the concave side of the geometry, up to 15% for the phantom with the smallest radius. On the convex side of the applicator, delivered doses were up to 10% lower for small treated areas ({<=} 5 catheters) but, interestingly, the dose error was negligible for large treated areas (>5 catheters). Our measurements have shown inaccuracy in dose delivery when the original planar treatment plan is delivered with a curved applicator. Dose delivery errors arising from the use of planar treatment plans with curved applicators may be significant.
Shi, Junli; Xia, Yonggao; Yuan, Zhizhang; Hu, Huasheng; Li, Xianfeng; Zhang, Huamin; Liu, Zhaoping
2015-01-01
Separators with high reliability and security are in urgent demand for the advancement of high performance lithium ion batteries. Here, we present a new and practical porous membrane with three-dimension (3D) heat-resistant skeleton and high curvature pore structure as a promising separator candidate to facilitate advances in battery safety and performances beyond those obtained from the conventional separators. The unique material properties combining with the well-developed structural characteristics enable the 3D porous skeleton to own several favorable properties, including superior thermal stability, good wettability with liquid electrolyte, high ion conductivity and internal short-circuit protection function, etc. which give rise to acceptable battery performances. Considering the simply and cost-effective preparation process, the porous membrane is deemed to be an interesting direction for the future lithium ion battery separator. PMID:25653104
Shi, Junli; Xia, Yonggao; Yuan, Zhizhang; Hu, Huasheng; Li, Xianfeng; Zhang, Huamin; Liu, Zhaoping
2015-01-01
Separators with high reliability and security are in urgent demand for the advancement of high performance lithium ion batteries. Here, we present a new and practical porous membrane with three-dimension (3D) heat-resistant skeleton and high curvature pore structure as a promising separator candidate to facilitate advances in battery safety and performances beyond those obtained from the conventional separators. The unique material properties combining with the well-developed structural characteristics enable the 3D porous skeleton to own several favorable properties, including superior thermal stability, good wettability with liquid electrolyte, high ion conductivity and internal short-circuit protection function, etc. which give rise to acceptable battery performances. Considering the simply and cost-effective preparation process, the porous membrane is deemed to be an interesting direction for the future lithium ion battery separator. PMID:25653104
Spatial curvature endgame: Reaching the limit of curvature determination
NASA Astrophysics Data System (ADS)
Leonard, C. Danielle; Bull, Philip; Allison, Rupert
2016-07-01
Current constraints on spatial curvature show that it is dynamically negligible: |ΩK|≲5 ×10-3 (95% C.L.). Neglecting it as a cosmological parameter would be premature however, as more stringent constraints on ΩK at around the 10-4 level would offer valuable tests of eternal inflation models and probe novel large-scale structure phenomena. This precision also represents the "curvature floor," beyond which constraints cannot be meaningfully improved due to the cosmic variance of horizon-scale perturbations. In this paper, we discuss what future experiments will need to do in order to measure spatial curvature to this maximum accuracy. Our conservative forecasts show that the curvature floor is unreachable—by an order of magnitude—even with Stage IV experiments, unless strong assumptions are made about dark energy evolution and the Λ CDM parameter values. We also discuss some of the novel problems that arise when attempting to constrain a global cosmological parameter like ΩK with such high precision. Measuring curvature down to this level would be an important validation of systematics characterization in high-precision cosmological analyses.
Curvature effects on the stability of laminar boundary layers on swept wings
NASA Technical Reports Server (NTRS)
Collier, F. S., Jr.; Bartlett, D. W.; Wagner, R. D.
1989-01-01
The stability of the laminar boundary layer on a swept wing is examined. An improved linear stability theory which includes the effects of body and streamline curvature and compressibility is utilized for the calculations. The computed N-factor is correlated with the onset of transition. For this study, only test conditions where transition is due to the growth of highly amplified crossflow instabilities on convex surfaces are examined. The calculations show that the effect of the curvature terms is to dramatically reduce local amplification rates in regions where body and streamline curvature are large. For the cases where transition occurred ahead of the pressure minimum on the upper surface of the wing, the N-factor at transition onset is near 9 when the effects of body and streamline curvature are included in the computations. When the curvature terms are neglected, the average N-factor is about 17. The calculations show that traveling crossflow waves are most amplified.
Keckes, J.; Eiper, E.; Martinschitz, K. J.; Koestenbauer, H.; Daniel, R.; Mitterer, C.
2007-03-15
A new x-ray technique to determine temperature dependencies of macroscopic stresses in thin films by characterizing the substrate curvature is introduced. The technique is demonstrated on polycrystalline TiN and Al thin films deposited on Si(100) wafers. The structures are thermally cycled in the temperature range of 25-400 deg. C using a newly developed heating chamber attached to a commercial x-ray diffractometer. The curvature of the freestanding samples was determined by the rocking curve measurement of substrate Si 400 reflections at different lateral positions of the samples, and the stresses are calculated using Stoney's formula. The results show that the magnitude of the stress is in good agreement with the results obtained by other techniques. For the practical application of the technique, the sample mounting and the temperature control are of great importance.
On the Weyl curvature hypothesis
Stoica, Ovidiu Cristinel
2013-11-15
The Weyl curvature hypothesis of Penrose attempts to explain the high homogeneity and isotropy, and the very low entropy of the early universe, by conjecturing the vanishing of the Weyl tensor at the Big-Bang singularity. In previous papers it has been proposed an equivalent form of Einstein’s equation, which extends it and remains valid at an important class of singularities (including in particular the Schwarzschild, FLRW, and isotropic singularities). Here it is shown that if the Big-Bang singularity is from this class, it also satisfies the Weyl curvature hypothesis. As an application, we study a very general example of cosmological models, which generalizes the FLRW model by dropping the isotropy and homogeneity constraints. This model also generalizes isotropic singularities, and a class of singularities occurring in Bianchi cosmologies. We show that the Big-Bang singularity of this model is of the type under consideration, and satisfies therefore the Weyl curvature hypothesis. -- Highlights: •The singularities we introduce are described by finite geometric/physical objects. •Our singularities have smooth Riemann and Weyl curvatures. •We show they satisfy Penrose’s Weyl curvature hypothesis (Weyl=0 at singularities). •Examples: FLRW, isotropic singularities, an extension of Schwarzschild’s metric. •Example: a large class of singularities which may be anisotropic and inhomogeneous.
Spatial curvature falsifies eternal inflation
NASA Astrophysics Data System (ADS)
Kleban, Matthew; Schillo, Marjorie
2012-06-01
Inflation creates large-scale cosmological density perturbations that are characterized by an isotropic, homogeneous, and Gaussian random distribution about a locally flat background. Even in a flat universe, the spatial curvature measured within one Hubble volume receives contributions from long wavelength perturbations, and will not in general be zero. These same perturbations determine the Cosmic Microwave Background (CMB) temperature fluctuations, which are Script O(10-5). Consequently, the low-l multipole moments in the CMB temperature map predict the value of the measured spatial curvature Ωk. On this basis we argue that a measurement of |Ωk| > 10-4 would rule out slow-roll eternal inflation in our past with high confidence, while a measurement of Ωk < -10-4 (which is positive curvature, a locally closed universe) rules out false-vacuum eternal inflation as well, at the same confidence level. In other words, negative curvature (a locally open universe) is consistent with false-vacuum eternal inflation but not with slow-roll eternal inflation, and positive curvature falsifies both. Near-future experiments will dramatically extend the sensitivity of Ωk measurements and constitute a sharp test of these predictions.
Membrane curvature at a glance.
McMahon, Harvey T; Boucrot, Emmanuel
2015-03-15
Membrane curvature is an important parameter in defining the morphology of cells, organelles and local membrane subdomains. Transport intermediates have simpler shapes, being either spheres or tubules. The generation and maintenance of curvature is of central importance for maintaining trafficking and cellular functions. It is possible that local shapes in complex membranes could help to define local subregions. In this Cell Science at a Glance article and accompanying poster, we summarize how generating, sensing and maintaining high local membrane curvature is an active process that is mediated and controlled by specialized proteins using general mechanisms: (i) changes in lipid composition and asymmetry, (ii) partitioning of shaped transmembrane domains of integral membrane proteins or protein or domain crowding, (iii) reversible insertion of hydrophobic protein motifs, (iv) nanoscopic scaffolding by oligomerized hydrophilic protein domains and, finally, (v) macroscopic scaffolding by the cytoskeleton with forces generated by polymerization and by molecular motors. We also summarize some of the discoveries about the functions of membrane curvature, where in addition to providing cell or organelle shape, local curvature can affect processes like membrane scission and fusion as well as protein concentration and enzyme activation on membranes. PMID:25774051
x-y curvature wavefront sensor.
Cagigal, Manuel P; Valle, Pedro J
2015-04-15
In this Letter, we propose a new curvature wavefront sensor based on the principles of optical differentiation. The theoretically modeled setup consists of a diffractive optical mask placed at the intermediate plane of a classical two-lens coherent optical processor. The resulting image is composed of a number of local derivatives of the entrance pupil function whose proper combination provides the wavefront curvature. In contrast to the common radial curvature sensors, this one is able to provide the x and y wavefront curvature maps simultaneously. The sensor offers other additional advantages like having high spatial resolution, adjustable dynamic range, and not being sensitive to misalignment. PMID:25872040
Spatial curvature, spacetime curvature, and gravity
NASA Astrophysics Data System (ADS)
Price, Richard H.
2016-08-01
The belief that curved spacetime gravity cannot be simply and correctly presented results in such misleading presentations as elastic two-dimensional sheets deformed as they support heavy objects. This article attempts to show that the conceptual basis of curved spacetime gravity can be simply and correctly presented, and that the spatial curvature of a deformed elastic sheet is very different from the spacetime curvature underlying gravity. This article introduces the idea of a "splittable" spacetime that has spatial curvature, but is missing most of the manifestations of gravity. A section in which no mathematics is used is directed at students who have studied no more than introductory physics. A separate section, for students who have taken only an introductory course in general relativity, gives mathematical arguments centering on splittable spacetimes.
NASA Astrophysics Data System (ADS)
Trouw, Rudolph A. J.; Tavares, Felipe M.; Robyr, Martin
2008-08-01
This paper presents numerical data from garnets with inclusion trail curvature angles of up to 260°. Three hundred and twenty-five garnets were studied from an outcrop of greenschist facies phyllite in southern Minas Gerais State, Brazil. Apart from the inclusion trail curvature angle α, also the aspect ratio R and the angle between the long axis of the garnets and the foliation, β, were measured. The results show a remarkable concentration of α at 180° and a minor one at 90°. R varies between 1 and 2 showing that the garnets deviate from sphericity and β shows that all garnets have their long axis in the "forward rotated" quadrant, supporting the rotational interpretation. A model is proposed to explain the concentrations of α, based on preferential growth of the garnets into the mica rich strain caps, orthogonal to the foliation, causing elongated crystals that, because of their shape and position would experience accelerated rotation until relatively stable positions with their long axes parallel to the foliation would be attained. Renewed growth, again into the mica-rich strain caps, orthogonal to the foliation would first restore the spherical shape and then produce an elongated shape, again perpendicular to the foliation, forcing a repetition of the process. It is concluded that this model is capable of explaining the concentration of α in multiples of 90°, in a rotational model, where this concentration was considered earlier as an argument in favor of the non-rotational model.
Curvature of the penis is an abnormal bend in the penis that occurs during erection. It is also called Peyronie's disease. ... tissue develops in the deep tissues of the penis. The cause of this fibrous tissue is often ...
Chrometzka, P
1967-12-01
1. High atmospheric pressure causes an increase of the 3-indoleacetic-acid-induced curvature of Avena coleoptiles in the Went-test, regardless of whether the applied gas is nitrogen, hydrogen, oxygen, or air. 2. The highest increase was caused by high pressure of oxygen, the lowest by lack of oxygen. 3. The high pressure effect was also observed with coleoptiles which were treated 20 hours prior to the test and which were then kept under normal pressure. 4. High pressure of oxygen for a long period (20 hours) had a poisonous effect on the coleoptiles. They ceased to grow. Preliminary studies have shown that the respiration is enhanced if the coleoptiles have been kept under high pressure. PMID:24554325
Ueki, Ayaka; Kidoaki, Satoru
2015-02-01
Directional cell migration induced by the stiffness gradient of cell culture substrates is known as a subset of the mechanical-cue-induced taxis, so-called mechanotaxis, typically durotaxis toward hard region. To establish the general conditions of biomaterials to manipulate the mechanotaxis, the effect of the shape of the elasticity transition boundary between hard and soft regions of a substrate on mechanotaxis should be systematically determined as well as the conditions of elasticity gradient strength. Here, as a simplified factor of expressing variations in the shape of the elasticity boundary in living tissues, we focus on the curvature of the elasticity boundary. Mask-free photolithographic microelasticity patterning of photocurable gelatin gel was employed to systematically prepare elasticity boundaries with various curvatures, and the efficiency of mechanotaxis of fibroblast cells around each curved boundary was examined. Highly efficient usual durotaxis was induced on a convex boundary with 100 μm in radius and on a concave boundary with 750 μm in radius of curvature. Interestingly, biased migration toward soft regions of the gel, i.e., inverse durotaxis, was first observed for concave boundaries with 50 μm or 100 μm in radius of curvature, which was named as "negative mechanotaxis". The curvature of the elasticity boundary was found to markedly affect the efficiency of induction and the direction of mechanotaxis. The mechanism responsible for this phenomenon and the implication for the curvature effect in in vivo systems are discussed. PMID:25522964
Effects of streamline curvature on separation prediction
NASA Astrophysics Data System (ADS)
Arolla, Sunil K.; Durbin, Paul A.
2009-11-01
In this study, the effects of streamline curvature on prediction of flow separation are investigated. The geometry is a circulation control airfoil, a high-lift configuration that has been under extensive research for more than two decades. A tangential jet is blown over a thick, rounded trailing edge, using the Coanda effect to delay separation. An attempt is made to understand, through numerical simulations, the dynamics of turbulent separation and reattachment on the Coanda surface. Highly curved, attached recirculation regions are seen to form. A physics based curvature correction proposed by Pettersson-Reif et al. (1999) is used in conjunction with ζ-f turbulence model. The chord-based Reynolds number is Re = 10^6. Two jet momentum coefficients of Cμ=0.03 and 0.1 are computed. In this paper, comparisons between the computed and experimental pressure distributions, velocity profiles and the position of flow detachment are presented. Comparisons with other closures such as Menter's SST model are also discussed.
Visually discerning the curvature of the Earth.
Lynch, David K
2008-12-01
Reports and photographs claiming that visual observers can detect the curvature of the Earth from high mountains or high-flying commercial aircraft are investigated. Visual daytime observations show that the minimum altitude at which curvature of the horizon can be detected is at or slightly below 35,000 ft, providing that the field of view is wide (60 degrees ) and nearly cloud free. The high-elevation horizon is almost as sharp as the sea-level horizon, but its contrast is less than 10% that of the sea-level horizon. Photographs purporting to show the curvature of the Earth are always suspect because virtually all camera lenses project an image that suffers from barrel distortion. To accurately assess curvature from a photograph, the horizon must be placed precisely in the center of the image, i.e., on the optical axis. PMID:19037349
Nakama, Tomohiro; Harada, Tomohiro; Polnarev, A.G.; Yokoyama, Jun'ichi E-mail: harada@rikkyo.ac.jp E-mail: yokoyama@resceu.s.u-tokyo.ac.jp
2014-01-01
Primordial black holes (PBHs) are an important tool in cosmology to probe the primordial spectrum of small-scale curvature perturbations that reenter the cosmological horizon during radiation domination epoch. We numerically solve the evolution of spherically symmetric highly perturbed configurations to clarify the criteria of PBHs formation using an extremely wide class of curvature profiles characterized by five parameters, (in contrast to only two parameters used in all previous papers) which specify the curvature profiles not only at the central region but also at the outer boundary of configurations. It is shown that formation or non-formation of PBHs is determined essentialy by only two master parameters one of which can be presented as an integral of curvature over initial configurations and the other is presented in terms of the position of the boundary and the edge of the core.
Barenboim, Gabriela; Martínez, Enrique Fernández; Mena, Olga; Verde, Licia E-mail: enfmarti@mppmu.mpg.de E-mail: liciaverde@icc.ub.edu
2010-03-01
Geometrical tests such as the combination of the Hubble parameter H(z) and the angular diameter distance d{sub A}(z) can, in principle, break the degeneracy between the dark energy equation of state parameter w(z), and the spatial curvature Ω{sub k} in a direct, model-independent way. In practice, constraints on these quantities achievable from realistic experiments, such as those to be provided by Baryon Acoustic Oscillation (BAO) galaxy surveys in combination with CMB data, can resolve the cosmic confusion between the dark energy equation of state parameter and curvature only statistically and within a parameterized model for w(z). Combining measurements of both H(z) and d{sub A}(z) up to sufficiently high redshifts z ∼ 2 and employing a parameterization of the redshift evolution of the dark energy equation of state are the keys to resolve the w(z)−Ω{sub k} degeneracy.
Curvature and torsion in growing actin networks
NASA Astrophysics Data System (ADS)
Shaevitz, Joshua W.; Fletcher, Daniel A.
2008-06-01
Intracellular pathogens such as Listeria monocytogenes and Rickettsia rickettsii move within a host cell by polymerizing a comet-tail of actin fibers that ultimately pushes the cell forward. This dense network of cross-linked actin polymers typically exhibits a striking curvature that causes bacteria to move in gently looping paths. Theoretically, tail curvature has been linked to details of motility by considering force and torque balances from a finite number of polymerizing filaments. Here we track beads coated with a prokaryotic activator of actin polymerization in three dimensions to directly quantify the curvature and torsion of bead motility paths. We find that bead paths are more likely to have low rather than high curvature at any given time. Furthermore, path curvature changes very slowly in time, with an autocorrelation decay time of 200 s. Paths with a small radius of curvature, therefore, remain so for an extended period resulting in loops when confined to two dimensions. When allowed to explore a three-dimensional (3D) space, path loops are less evident. Finally, we quantify the torsion in the bead paths and show that beads do not exhibit a significant left- or right-handed bias to their motion in 3D. These results suggest that paths of actin-propelled objects may be attributed to slow changes in curvature, possibly associated with filament debranching, rather than a fixed torque.
NASA Astrophysics Data System (ADS)
Aleksić, J.; Ansoldi, S.; Antonelli, L. A.; Antoranz, P.; Babic, A.; Bangale, P.; Barrio, J. A.; Becerra González, J.; Bednarek, W.; Bernardini, E.; Biasuzzi, B.; Biland, A.; Blanch, O.; Bonnefoy, S.; Bonnoli, G.; Borracci, F.; Bretz, T.; Carmona, E.; Carosi, A.; Colin, P.; Colombo, E.; Contreras, J. L.; Cortina, J.; Covino, S.; da Vela, P.; Dazzi, F.; de Angelis, A.; de Caneva, G.; de Lotto, B.; de Oña Wilhelmi, E.; Delgado Mendez, C.; Dominis Prester, D.; Dorner, D.; Doro, M.; Einecke, S.; Eisenacher, D.; Elsaesser, D.; Fidalgo, D.; Fonseca, M. V.; Font, L.; Frantzen, K.; Fruck, C.; Galindo, D.; García López, R. J.; Garczarczyk, M.; Garrido Terrats, D.; Gaug, M.; Godinović, N.; González Muñoz, A.; Gozzini, S. R.; Hadasch, D.; Hanabata, Y.; Hayashida, M.; Herrera, J.; Hildebrand, D.; Hose, J.; Hrupec, D.; Idec, W.; Kadenius, V.; Kellermann, H.; Knoetig, M. L.; Kodani, K.; Konno, Y.; Krause, J.; Kubo, H.; Kushida, J.; La Barbera, A.; Lelas, D.; Lewandowska, N.; Lindfors, E.; Lombardi, S.; Longo, F.; López, M.; López-Coto, R.; López-Oramas, A.; Lorenz, E.; Lozano, I.; Makariev, M.; Mallot, K.; Maneva, G.; Mannheim, K.; Maraschi, L.; Marcote, B.; Mariotti, M.; Martínez, M.; Mazin, D.; Menzel, U.; Miranda, J. M.; Mirzoyan, R.; Moralejo, A.; Munar-Adrover, P.; Nakajima, D.; Neustroev, V.; Niedzwiecki, A.; Nilsson, K.; Nishijima, K.; Noda, K.; Orito, R.; Overkemping, A.; Paiano, S.; Palatiello, M.; Paneque, D.; Paoletti, R.; Paredes, J. M.; Paredes-Fortuny, X.; Persic, M.; Poutanen, J.; Prada Moroni, P. G.; Prandini, E.; Puljak, I.; Reinthal, R.; Rhode, W.; Ribó, M.; Rico, J.; Rodriguez Garcia, J.; Rügamer, S.; Saito, T.; Saito, K.; Satalecka, K.; Scalzotto, V.; Scapin, V.; Schultz, C.; Schweizer, T.; Sillanpää, A.; Sitarek, J.; Snidaric, I.; Sobczynska, D.; Spanier, F.; Stamerra, A.; Steinbring, T.; Storz, J.; Strzys, M.; Takalo, L.; Takami, H.; Tavecchio, F.; Temnikov, P.; Terzić, T.; Tescaro, D.; Teshima, M.; Thaele, J.; Tibolla, O.; Torres, D. F.; Toyama, T.; Treves, A.; Vogler, P.; Will, M.; Zanin, R.; MAGIC Collaboration; D'Ammando, F.; Buson, S.; Lähteenmäki, A.; Tornikoski, M.; Hovatta, T.; Readhead, A. C. S.; Max-Moerbeck, W.; Richards, J. L.
2015-07-01
PG 1553+113 is a very high energy (VHE, E > 100 GeV) γ-ray emitter classified as a BL Lac object. Its redshift is constrained by intergalactic absorption lines in the range 0.4 < z < 0.58. The MAGIC telescopes have monitored the source's activity since 2005. In early 2012, PG 1553+113 was found in a high state, and later, in April of the same year, the source reached its highest VHE flux state detected so far. Simultaneous observations carried out in X-rays during 2012 April show similar flaring behaviour. In contrast, the γ-ray flux at E < 100 GeV observed by Fermi-LAT is compatible with steady emission. In this paper, a detailed study of the flaring state is presented. The VHE spectrum shows clear curvature, being well fitted either by a power law with an exponential cut-off or by a log-parabola. A simple power-law fit hypothesis for the observed shape of the PG 1553+113 VHE γ-ray spectrum is rejected with a high significance (fit probability P = 2.6 × 10-6). The observed curvature is compatible with the extragalactic background light (EBL) imprint predicted by current generation EBL models assuming a redshift z ˜ 0.4. New constraints on the redshift are derived from the VHE spectrum. These constraints are compatible with previous limits and suggest that the source is most likely located around the optical lower limit, z = 0.4, based on the detection of Lyα absorption. Finally, we find that the synchrotron self-Compton model gives a satisfactory description of the observed multiwavelength spectral energy distribution during the flare.
Curvature calculations with GEOCALC
NASA Astrophysics Data System (ADS)
Moussiaux, A.; Tombal, Ph.
1987-04-01
A new method for calculating the curvature tensor has been recently proposed by D. Hestenes. This method is a particular application of geometric calculus, which has been implemented in an algebraic programming language on the form of a package called GEOCALC. We show how to apply this package to the Schwarzchild case and we discuss the different results.
Curvature calculations with GEOCALC
Moussiaux, A.; Tombal, P.
1987-04-01
A new method for calculating the curvature tensor has been recently proposed by D. Hestenes. This method is a particular application of geometric calculus, which has been implemented in an algebraic programming language on the form of a package called GEOCALC. They show how to apply this package to the Schwarzchild case and they discuss the different results.
NASA Astrophysics Data System (ADS)
Yu, Peter; Eyles, Nick; Sookhan, Shane
2015-10-01
Resolving the origin(s) of drumlins and related megaridges in areas of megascale glacial lineations (MSGL) left by paleo-ice sheets is critical to understanding how ancient ice sheets interacted with their sediment beds. MSGL is now linked with fast-flowing ice streams but there is a broad range of erosional and depositional models. Further progress is reliant on constraining fluxes of subglacial sediment at the ice sheet base which in turn is dependent on morphological data such as landform shape and elongation and most importantly landform volume. Past practice in determining shape has employed a broad range of geomorphological methods from strictly visualisation techniques to more complex semi-automated and automated drumlin extraction methods. This paper reviews and builds on currently available visualisation, semi-automated and automated extraction methods and presents a new, Curvature Based Relief Separation (CBRS) technique; for drumlin mapping. This uses curvature analysis to generate a base level from which topography can be normalized and drumlin volume can be derived. This methodology is tested using a high resolution (3 m) LiDAR elevation dataset from the Wadena Drumlin Field, Minnesota, USA, which was constructed by the Wadena Lobe of the Laurentide Ice Sheet ca. 20,000 years ago and which as a whole contains ~ 2000 drumlins across an area of ~ 7500 km2. This analysis demonstrates that CBRS provides an objective and robust procedure for automated drumlin extraction. There is strong agreement with manually selected landforms but the method is also capable of resolving features that were not detectable manually thereby considerably expanding the known population of streamlined landforms. CBRS provides an effective automatic method for visualisation of large areas of the streamlined beds of former ice sheets and for modelling sediment fluxes below ice sheets.
Curvature Sorting of Peripheral Proteins on Solid-Supported Wavy Membranes
Hsieh, Wan-Ting; Hsu, Chih-Jung; Capraro, Benjamin R.; Wu, Tingting; Chen, Chi-Mon; Yang, Shu; Baumgart, Tobias
2013-01-01
Cellular membrane deformation and the associated redistribution of membrane-bound proteins are important aspects of membrane function. Current model membrane approaches for studying curvature sensing are limited to positive curvatures, and often require complex and delicate experimental setups. To overcome these challenges, we fabricated a wavy substrate imposing a range of curvatures onto an adhering lipid bilayer membrane. We examined the curvature sorting of several peripheral proteins binding to the wavy membrane and observed them to partition into distinct regions of curvature. Furthermore, single molecule imaging experiments suggested that curvature sensing of proteins on low-curvature substrates requires cooperative interactions. PMID:22881196
2011-01-01
Background Due to its overarching role in genome function, sequence-dependent DNA curvature continues to attract great attention. The DNA double helix is not a rigid cylinder, but presents both curvature and flexibility in different regions, depending on the sequence. More in depth knowledge of the various orders of complexity of genomic DNA structure has allowed the design of sophisticated bioinformatics tools for its analysis and manipulation, which, in turn, have yielded a better understanding of the genome itself. Curved DNA is involved in many biologically important processes, such as transcription initiation and termination, recombination, DNA replication, and nucleosome positioning. CpG islands and tandem repeats also play significant roles in the dynamics and evolution of genomes. Results In this study, we analyzed the relationship between these three structural features within rice (Oryza sativa) and Arabidopsis (Arabidopsis thaliana) genomes. A genome-scale prediction of curvature distribution in rice and Arabidopsis indicated that most of the chromosomes of both genomes have maximal chromosomal DNA curvature adjacent to the centromeric region. By analyzing tandem repeats across the genome, we found that frequencies of repeats are higher in regions adjacent to those with high curvature value. Further analysis of CpG islands shows a clear interdependence between curvature value, repeat frequencies and CpG islands. Each CpG island appears in a local minimal curvature region, and CpG islands usually do not appear in the centromere or regions with high repeat frequency. A statistical evaluation demonstrates the significance and non-randomness of these features. Conclusions This study represents the first systematic genome-scale analysis of DNA curvature, CpG islands and tandem repeats at the DNA sequence level in plant genomes, and finds that not all of the chromosomes in plants follow the same rules common to other eukaryote organisms, suggesting that some
Unfolding the Berry curvature of supercell calculations
NASA Astrophysics Data System (ADS)
Bianco, Raffaello; Resta, Raffaele; Souza, Ivo
2014-03-01
Unfolding band structures of supercell calculations has become a valuable tool for visualizing the influence of point impurities on the electronic states in crystals. In the same spirit, we introduce a procedure which maps the k-space Berry curvature of the occupied states from the small BZ of a supercell onto the normal BZ of the perfect (or virtual) crystal. As an application, we analyze the k-space distribution of the unfolded curvature of bcc Fe1-xCox ordered alloys, to better understand the influence of alloying on the anomalous Hall conductivity. Comparing with the ordinary curvature calculated in the virtual-crystal approximation, we find that the lowering of translational symmetry by the Co ``impurities'' introduces ``extrinsic'' contributions, which correlate with changes in the spectral function near the Fermi surface. In particular, the unfolded curvature displays additional sharp peaks associated with low-energy pseudovertical transitions. These occur in regions of k-space where two unfolded bands, which in the virtual crystal would be separated in k-space (and therefore would not jointly contribute to its Berry curvature), lie on either side of the Fermi level and are coupled by the impurity potential.
Curvature constraints from the causal entropic principle
Bozek, Brandon; Albrecht, Andreas; Phillips, Daniel
2009-07-15
Current cosmological observations indicate a preference for a cosmological constant that is drastically smaller than what can be explained by conventional particle physics. The causal entropic principle (Bousso et al.) provides an alternative approach to anthropic attempts to predict our observed value of the cosmological constant by calculating the entropy created within a causal diamond. We have extended this work to use the causal entropic principle to predict the preferred curvature within the 'multiverse'. We have found that values larger than {rho}{sub k}=40{rho}{sub m} are disfavored by more than 99.99% peak value at {rho}{sub {lambda}}=7.9x10{sup -123} and {rho}{sub k}=4.3{rho}{sub m} for open universes. For universes that allow only positive curvature or both positive and negative curvature, we find a correlation between curvature and dark energy that leads to an extended region of preferred values. Our universe is found to be disfavored to an extent depending on the priors on curvature. We also provide a comparison to previous anthropic constraints on open universes and discuss future directions for this work.
Design considerations for adjustable-curvature, high-power, X-ray mirrors based on elastic bending
NASA Astrophysics Data System (ADS)
Howells, Malcolm R.; Lunt, David
1993-08-01
The use of elastic bending to form the shapes of high-power X-ray mirrors for synchrotron radiation beamlines is considered. An approach in which the bending mechanism and the mirror are cut from the same monolithic block by electric-discharge-machining techniques is especially advocated. A discussion of the theory and practical design philosophies is given that includes circular and elliptical cylinder mirrors. The influence of gravity on the mirror shape is studied with emphasis on the optimum positions for the mirror supports that, for a uniform mirror, turn out to be at a spacing equal to the mirror length divided by root three.
The Hydrophobic Insertion Mechanism of Membrane Curvature Generation by Proteins
Campelo, Felix; McMahon, Harvey T.; Kozlov, Michael M.
2008-01-01
A wide spectrum of intracellular processes is dependent on the ability of cells to dynamically regulate membrane shape. Membrane bending by proteins is necessary for the generation of intracellular transport carriers and for the maintenance of otherwise intrinsically unstable regions of high membrane curvature in cell organelles. Understanding the mechanisms by which proteins curve membranes is therefore of primary importance. Here we suggest, for the first time to our knowledge, a quantitative mechanism of lipid membrane bending by hydrophobic or amphipathic rodlike inclusions which simulate amphipathic α-helices—structures shown to sculpt membranes. Considering the lipid monolayer matrix as an anisotropic elastic material, we compute the intramembrane stresses and strains generated by the embedded inclusions, determine the resulting membrane shapes, and the accumulated elastic energy. We characterize the ability of an inclusion to bend membranes by an effective spontaneous curvature, and show that shallow rodlike inclusions are more effective in membrane shaping than are lipids having a high propensity for curvature. Our computations provide experimentally testable predictions on the protein amounts needed to generate intracellular membrane shapes for various insertion depths and membrane thicknesses. We also predict that the ability of N-BAR domains to produce membrane tubules in vivo can be ascribed solely to insertion of their amphipathic helices. PMID:18515373
Canards and curvature: nonsmooth approximation by pinching
NASA Astrophysics Data System (ADS)
Desroches, M.; Jeffrey, M. R.
2011-05-01
In multiple time-scale (singularly perturbed) dynamical systems, canards are counterintuitive solutions that evolve along both attracting and repelling invariant manifolds. In two dimensions, canards result in periodic oscillations whose amplitude and period grow in a highly nonlinear way: they are slowly varying with respect to a control parameter, except for an exponentially small range of values where they grow extremely rapidly. This sudden growth, called a canard explosion, has been encountered in many applications ranging from chemistry to neuronal dynamics, aerospace engineering and ecology. Canards were initially studied using nonstandard analysis, and later the same results were proved by standard techniques such as matched asymptotics, invariant manifold theory and parameter blow-up. More recently, canard-like behaviour has been linked to surfaces of discontinuity in piecewise-smooth dynamical systems. This paper provides a new perspective on the canard phenomenon by showing that the nonstandard analysis of canard explosions can be recast into the framework of piecewise-smooth dynamical systems. An exponential coordinate scaling is applied to a singularly perturbed system of ordinary differential equations. The scaling acts as a lens that resolves dynamics across all time-scales. The changes of local curvature that are responsible for canard explosions are then analysed. Regions where different time-scales dominate are separated by hypersurfaces, and these are pinched together to obtain a piecewise-smooth system, in which curvature changes manifest as discontinuity-induced bifurcations. The method is used to classify canards in arbitrary dimensions, and to derive the parameter values over which canards form either small cycles (canards without head) or large cycles (canards with head).
Asymptotic behavior of curvature of surface elements in isotropic turbulence
NASA Technical Reports Server (NTRS)
Girimaji, S. S.
1991-01-01
The asymptotic behavior of the curvature of material elements in turbulence is investigated using Lagrangian velocity-gradient time series obtained from direct numerical simulations of isotropic turbulence. Several material-element ensembles of different initial curvatures and shapes are studied. It is found that, at long times, the (first five) moments of the logarithm of characteristic curvature and shape factor asymptote to values that are independent of the initial curvature or shape. This evidence strongly suggests that the asymptotic pdf's of the curvature and shape of material elements are stationary and independent of initial conditions. Irrespective of initial curvature or shape, the asymptotic shape of a material surface is cylindrical with a high probability.
NASA Technical Reports Server (NTRS)
Simon, T. W.; Volino, R. J.
2007-01-01
Experiments on boundary layer transition with flat, concave and convex walls and various levels of free-stream disturbance and with zero and strong streamwise acceleration have been conducted. Measurements of both fluid mechanics and heat transfer processes were taken. Examples are profiles of mean velocity and temperature; Reynolds normal and shear stresses; turbulent streamwise and cross-stream heat fluxed; turbulent Prandtl number; and streamwise variations of wall skin friction and heat transfer coefficient values. Free-stream turbulence levels were varied over the range from about 0.3 percent to about 8 percent. The effects of curvature on the onset of transition under low disturbance conditions are clear; concave curvature leads to an earlier and more rapid transition and the opposite is true for convex curvature This was previously known but little documentation of the transport processes in the flow was available
Improving the Sensitivity of Astronomical Curvature Wavefront Sensor Using Dual-Stroke Curvature
NASA Astrophysics Data System (ADS)
Guyon, Olivier; Blain, Celia; Takami, Hideki; Hayano, Yutaka; Hattori, Masayuki; Watanabe, Makoto
2008-06-01
Curvature wavefront sensors measure wavefront phase aberration by acquiring two intensity images on either side of the pupil plane. Low-order adaptive optics (AO) systems using curvature wavefront sensing (CWFS) have proved to be highly efficient for astronomical applications: they are more sensitive, use fewer detector elements, and achieve, for the same number of actuators, higher Strehl ratios than AO systems using more traditional Shack-Hartmann wavefront sensors. In higher-order systems, however, curvature wavefront sensors lose sensitivity to low spatial frequencies wavefront aberrations. This effect, often described as "noise propagation," limits the usefulness of curvature wavefront sensing for high-order AO systems and/or large telescopes. In this paper, we first explain how this noise propagation effect occurs and then show that this limitation can be overcome by acquiring four defocused images of the pupil instead of two. This solution can be implemented without significant technology development and can run with a simple linear wavefront reconstruction algorithm at >kHz speed. We have successfully demonstrated in the laboratory that the four conjugation planes can be sequentially obtained at >kHz speed using a speaker-vibrating membrane assembly commonly used in current curvature AO systems. Closed loop simulations show that implementing this scheme is equivalent to making the guide star 1 to 1.5 magnitude brighter for the configuration tested (188 actuator elements on 8-m telescope). Higher sensitivity gains are expected on curvature systems with higher number of actuators.
Substrate Curvature Gradient Drives Rapid Droplet Motion
NASA Astrophysics Data System (ADS)
Lv, Cunjing; Chen, Chao; Chuang, Yin-Chuan; Tseng, Fan-Gang; Yin, Yajun; Grey, Francois; Zheng, Quanshui
2014-07-01
Making small liquid droplets move spontaneously on solid surfaces is a key challenge in lab-on-chip and heat exchanger technologies. Here, we report that a substrate curvature gradient can accelerate micro- and nanodroplets to high speeds on both hydrophilic and hydrophobic substrates. Experiments for microscale water droplets on tapered surfaces show a maximum speed of 0.42 m/s, 2 orders of magnitude higher than with a wettability gradient. We show that the total free energy and driving force exerted on a droplet are determined by the substrate curvature and substrate curvature gradient, respectively. Using molecular dynamics simulations, we predict nanoscale droplets moving spontaneously at over 100 m/s on tapered surfaces.
Substrate curvature gradient drives rapid droplet motion.
Lv, Cunjing; Chen, Chao; Chuang, Yin-Chuan; Tseng, Fan-Gang; Yin, Yajun; Grey, Francois; Zheng, Quanshui
2014-07-11
Making small liquid droplets move spontaneously on solid surfaces is a key challenge in lab-on-chip and heat exchanger technologies. Here, we report that a substrate curvature gradient can accelerate micro- and nanodroplets to high speeds on both hydrophilic and hydrophobic substrates. Experiments for microscale water droplets on tapered surfaces show a maximum speed of 0.42 m/s, 2 orders of magnitude higher than with a wettability gradient. We show that the total free energy and driving force exerted on a droplet are determined by the substrate curvature and substrate curvature gradient, respectively. Using molecular dynamics simulations, we predict nanoscale droplets moving spontaneously at over 100 m/s on tapered surfaces. PMID:25062213
Wavefront reconstruction from tangential and sagittal curvature.
Canales, Javier; Barbero, Sergio; Portilla, Javier; López-Alonso, José Manuel
2014-12-10
In a previous contribution [Appl. Opt.51, 8599 (2012)], a coauthor of this work presented a method for reconstructing the wavefront aberration from tangential refractive power data measured using dynamic skiascopy. Here we propose a new regularized least squares method where the wavefront is reconstructed not only using tangential but also sagittal curvature data. We prove that our new method provides improved quality reconstruction for typical and also for highly aberrated wavefronts, under a wide range of experimental error levels. Our method may be applied to any type of wavefront sensor (not only dynamic skiascopy) able to measure either just tangential or tangential plus sagittal curvature data. PMID:25608069
Curvature-processing network in macaque visual cortex
Yue, Xiaomin; Pourladian, Irene S.; Tootell, Roger B. H.; Ungerleider, Leslie G.
2014-01-01
Our visual environment abounds with curved features. Thus, the goal of understanding visual processing should include the processing of curved features. Using functional magnetic resonance imaging in behaving monkeys, we demonstrated a network of cortical areas selective for the processing of curved features. This network includes three distinct hierarchically organized regions within the ventral visual pathway: a posterior curvature-biased patch (PCP) located in the near-foveal representation of dorsal V4, a middle curvature-biased patch (MCP) located on the ventral lip of the posterior superior temporal sulcus (STS) in area TEO, and an anterior curvature-biased patch (ACP) located just below the STS in anterior area TE. Our results further indicate that the processing of curvature becomes increasingly complex from PCP to ACP. The proximity of the curvature-processing network to the well-known face-processing network suggests a possible functional link between them. PMID:25092328
Cosmic curvature and condensation
NASA Technical Reports Server (NTRS)
Harwit, Martin
1992-01-01
It is shown that the universe may consist of a patchwork of domains with different Riemann curvature constants k = 0, +/-1. Features of a phase transition in which flat space breaks up in a transition 2k0 - k(-) + k(+) with initial scale factors R(-) = R(+) are postulated and explored. It is shown that such a transition is energetically permitted, has the equivalent of a Curie temperature, and can lead in a natural way to the formation of voids and galaxies. It is predicted that, if the ambient universe on average is well fitted by a purely k(-) space, with only occasional domains of k(+) containing galaxies, a density parameter of (A(z sub c + 1)) super -1 should be expected, where z sub c represents the redshift of the earliest objects to have condensed, and A takes on values ranging from about 5 to 3. Present observations of quasars would suggest a density of about 0.03 or 0.05, respectively, but it could be lower if earlier condensation took place.
Astronomical redshifts of highly ionized regions
NASA Astrophysics Data System (ADS)
Hansen, Peter M.
2014-07-01
Astronomical or cosmological redshifts are an observable property of extragalactic objects and have historically been wholly attributed to the recessional velocity of that object. The question of other, or intrinsic, components of the redshift has been highly controversial since it was first proposed. This paper investigates one theoretical source of intrinsic redshift that has been identified. The highly ionized regions of Active Galactic Nuclei (AGN) and Quasi-Stellar Objects (QSO) are, by definition, plasmas. All plasmas have electromagnetic scattering characteristics that could contribute to the observed redshift. To investigate this possibility, one region of a generalized AGN was selected, the so called Broad Line Region (BLR). Even though unresolvable with current instrumentation, physical estimates of this region have been published for years in the astronomical literature. These data, selected and then averaged, are used to construct an overall model that is consistent with the published data to within an order of magnitude. The model is then subjected to a theoretical scattering investigation. The results suggest that intrinsic redshifts, derivable from the characteristics of the ambient plasma, may indeed contribute to the overall observed redshift of these objects.
Sigma models with negative curvature
NASA Astrophysics Data System (ADS)
Alonso, Rodrigo; Jenkins, Elizabeth E.; Manohar, Aneesh V.
2016-05-01
We construct Higgs Effective Field Theory (HEFT) based on the scalar manifold Hn, which is a hyperbolic space of constant negative curvature. The Lagrangian has a non-compact O (n , 1) global symmetry group, but it gives a unitary theory as long as only a compact subgroup of the global symmetry is gauged. Whether the HEFT manifold has positive or negative curvature can be tested by measuring the S-parameter, and the cross sections for longitudinal gauge boson and Higgs boson scattering, since the curvature (including its sign) determines deviations from Standard Model values.
Geometrical constraint on curvature with BAO experiments
NASA Astrophysics Data System (ADS)
Takada, Masahiro; Doré, Olivier
2015-12-01
The spatial curvature (K or ΩK) is one of the most fundamental parameters of an isotropic and homogeneous universe and has a close link to the physics of the early Universe. Combining the radial and angular diameter distances measured via the baryon acoustic oscillation (BAO) experiments allows us to unambiguously constrain the curvature. The method is primarily based on the metric theory, and is less sensitive to the theory of structure formation (other than the existence of the BAO scale) and is free of any model of dark energy. In this paper, we estimate a best achievable accuracy of constraining the curvature with the BAO experiments. We show that an all-sky, cosmic-variance-limited galaxy survey covering the Universe up to z ≳4 enables a precise determination of the curvature to an accuracy of σ (ΩK)≃1 0-3. When we assume a model of dark energy—either the cosmological constraint or the (w0,wa) model—it can achieve a precision of σ (ΩK)≃a few×10-4. These forecasts require a high sampling density of galaxies, and are degraded by up to a factor of a few for a survey with a finite number density of ˜10-3 (h /Mpc )3 .
Highlighting High Performance: Whitman Hanson Regional High School; Whitman, Massachusetts
Not Available
2006-06-01
This brochure describes the key high-performance building features of the Whitman-Hanson Regional High School. The brochure was paid for by the Massachusetts Technology Collaborative as part of their Green Schools Initiative. High-performance features described are daylighting and energy-efficient lighting, indoor air quality, solar and wind energy, building envelope, heating and cooling systems, water conservation, and acoustics. Energy cost savings are also discussed.
An Optical Method For Surface Curvature Testing
NASA Astrophysics Data System (ADS)
Jarisch, W.
1985-01-01
Inspection and measurement of surface quality play increasingly an important role in most machining and polishing processes. A typical example is the manufacturing of magnetic disks. The quality of a disk file essentially depends on the surface flatness of the substrate material. For many measurement aspects largearea topography variations are of less interest than high local changes of slope and curvature of the surface to be tested. Mathematically, the surface curvature is expressed as the second derivative of the profile function of the substrate, while the first derivative is known as the slope. Rapid local variations of the slope, that means high curvature values, cause high vertical accelerations of the magnetic head flying over the disk surface in fractions of a micrometer flight-height. Such irregularities of the substrate in the azimuthal disk direction would lead to uncontrolled fluctuations of the air gap between disk and head causing an attenuation of the write/read signal, to head vibrations, or even to a direct contact of the head with the disk (head crash). In the radial direction, the high-speed radial positioning of the head by voice coil driven motors also may cause a head crash at high local changes of the disk slope. Limits of the tolerable head accelerations, found by experience and theoretically by calculations, are listed in manufacturing specifications. For a fast, large area disk quality inspection and evaluation, a compact and highly sensitive measuring method has been developed. A testing tool based on this method displays the test area superimposed with a clear fringe pattern on a TV screen. The fringe pattern represents the surface curvature. From this, both components of the disk curvature, the azimuthal as well as the radial component, can be measured. Coherent optical interference and Moire techniques are the basic principles of the method providing the fringe pattern of the surface area under test. Each fringe interconnects
Spatial Control of Epsin-induced Clathrin Assembly by Membrane Curvature.
Holkar, Sachin S; Kamerkar, Sukrut C; Pucadyil, Thomas J
2015-06-01
Epsins belong to the family of highly conserved clathrin-associated sorting proteins that are indispensable for clathrin-mediated endocytosis, but their precise functions remain unclear. We have developed an assay system of budded supported membrane tubes displaying planar and highly curved membrane surfaces to analyze intrinsic membrane curvature preference shown by clathrin-associated sorting proteins. Using real-time fluorescence microscopy, we find that epsin preferentially partitions to and assembles clathrin on highly curved membrane surfaces. Sorting of epsin to regions of high curvature strictly depends on binding to phosphatidylinositol 4,5-bisphosphate. Fluorescently labeled clathrins rapidly assemble as foci, which in turn cluster epsin, while maintaining tube integrity. Clathrin foci grow in intensity with a typical time constant of ∼75 s, similar to the time scales for coated pit formation seen in cells. Epsin therefore effectively senses membrane curvature to spatially control clathrin assembly. Our results highlight the potential role of membrane curvature in orchestrating the myriad molecular interactions necessary for the success of clathrin-mediated membrane budding. PMID:25837255
Spatial Control of Epsin-induced Clathrin Assembly by Membrane Curvature*♦
Holkar, Sachin S.; Kamerkar, Sukrut C.; Pucadyil, Thomas J.
2015-01-01
Epsins belong to the family of highly conserved clathrin-associated sorting proteins that are indispensable for clathrin-mediated endocytosis, but their precise functions remain unclear. We have developed an assay system of budded supported membrane tubes displaying planar and highly curved membrane surfaces to analyze intrinsic membrane curvature preference shown by clathrin-associated sorting proteins. Using real-time fluorescence microscopy, we find that epsin preferentially partitions to and assembles clathrin on highly curved membrane surfaces. Sorting of epsin to regions of high curvature strictly depends on binding to phosphatidylinositol 4,5-bisphosphate. Fluorescently labeled clathrins rapidly assemble as foci, which in turn cluster epsin, while maintaining tube integrity. Clathrin foci grow in intensity with a typical time constant of ∼75 s, similar to the time scales for coated pit formation seen in cells. Epsin therefore effectively senses membrane curvature to spatially control clathrin assembly. Our results highlight the potential role of membrane curvature in orchestrating the myriad molecular interactions necessary for the success of clathrin-mediated membrane budding. PMID:25837255
Geodesic Curvature Effects in the WCMs
NASA Astrophysics Data System (ADS)
Zhou, Tianchun
2015-11-01
The favorable features of the steady state I-Regime discovered on Alcator C-Mod recently make this regime a hopeful working regime for future burning plasma experiments. Accompanying the I-regime are the weakly coherent modes (WCMs) with frequency around 200 kHz that propagate poloidally in the electron diamagnetic drift direction in the lab frame. The WCMs were interpreted as certain type of heavy impurity modes in the 3-fluid framework in a 1-D plane magnetic field geometry. Once considering in a simplified toroidal magnetic field geometry, the geodesic curvature will play important roles in that the contribution of the geodesic compression may catch up with or outweighs that of the parallel compression in the plasma edge region where the fluctuations are highly localized. This geodesic coupling to the neighboring bands modifies the marginal stability condition and mode profiles in Refs.. In the same framework, attempts will be made to interpret the concomitant low frequency (~ 20kHz) fluctuations as a type of impurity drift wave-like modes propagating in the ion diamagnetic drift direction. Supported by China National MCFE Research Program under Grant No. 2015GB11000.
Curvature calculations with spacetime algebra
Hestenes, D.
1986-06-01
A new method for calculating the curvature tensor is developed and applied to the Scharzschild case. The method employs Clifford algebra and has definite advantages over conventional methods using differential forms or tensor analysis.
Influence of Coanda surface curvature on performance of bladeless fan
NASA Astrophysics Data System (ADS)
Li, Guoqi; Hu, Yongjun; Jin, Yingzi; Setoguchi, Toshiaki; Kim, Heuy Dong
2014-10-01
The unique Coanda surface has a great influence on the performance of bladeless fan. However, there is few studies to explain the relationship between the performance and Coanda surface curvature at present. In order to gain a qualitative understanding of effect of the curvature on the performance of bladeless fan, numerical studies are performed in this paper. Firstly, three-dimensional numerical simulation is done by Fluent software. For the purpose to obtain detailed information of the flow field around the Coanda surface, two-dimensional numerical simulation is also conducted. Five types of Coanda surfaces with different curvature are designed, and the flow behaviour and the performance of them are analyzed and compared with those of the prototype. The analysis indicates that the curvature of Coanda surface is strongly related to blowing performance, It is found that there is an optimal curvature of Coanda surfaces among the studied models. Simulation result shows that there is a special low pressure region. With increasing curvature in Y direction, several low pressure regions gradually enlarged, then begin to merge slowly, and finally form a large area of low pressure. From the analyses of streamlines and velocity angle, it is found that the magnitude of the curvature affects the flow direction and reasonable curvature can induce fluid flow close to the wall. Thus, it leads to that the curvature of the streamlines is consistent with that of Coanda surface. Meanwhile, it also causes the fluid movement towards the most suitable direction. This study will provide useful information to performance improvements of bladeless fans.
Smrt, Sean T.; Draney, Adrian W.; Lorieau, Justin L.
2015-01-01
The highly conserved N-terminal 23 residues of the hemagglutinin glycoprotein, known as the fusion peptide domain (HAfp23), is vital to the membrane fusion and infection mechanism of the influenza virus. HAfp23 has a helical hairpin structure consisting of two tightly packed amphiphilic helices that rest on the membrane surface. We demonstrate that HAfp23 is a new class of amphipathic helix that functions by leveraging the negative curvature induced by two tightly packed helices on membranes. The helical hairpin structure has an inverted wedge shape characteristic of negative curvature lipids, with a bulky hydrophobic region and a relatively small hydrophilic head region. The F3G mutation reduces this inverted wedge shape by reducing the volume of its hydrophobic base. We show that despite maintaining identical backbone structures and dynamics as the wild type HAfp23, the F3G mutant has an attenuated fusion activity that is correlated to its reduced ability to induce negative membrane curvature. The inverted wedge shape of HAfp23 is likely to play a crucial role in the initial stages of membrane fusion by stabilizing negative curvature in the fusion stalk. PMID:25398882
Bavi, Omid; Cox, Charles D.; Vossoughi, Manouchehr; Naghdabadi, Reza; Jamali, Yousef; Martinac, Boris
2016-01-01
Mechanosensitive (MS) channels are ubiquitous molecular force sensors that respond to a number of different mechanical stimuli including tensile, compressive and shear stress. MS channels are also proposed to be molecular curvature sensors gating in response to bending in their local environment. One of the main mechanisms to functionally study these channels is the patch clamp technique. However, the patch of membrane surveyed using this methodology is far from physiological. Here we use continuum mechanics to probe the question of how curvature, in a standard patch clamp experiment, at different length scales (global and local) affects a model MS channel. Firstly, to increase the accuracy of the Laplace’s equation in tension estimation in a patch membrane and to be able to more precisely describe the transient phenomena happening during patch clamping, we propose a modified Laplace’s equation. Most importantly, we unambiguously show that the global curvature of a patch, which is visible under the microscope during patch clamp experiments, is of negligible energetic consequence for activation of an MS channel in a model membrane. However, the local curvature (RL < 50) and the direction of bending are able to cause considerable changes in the stress distribution through the thickness of the membrane. Not only does local bending, in the order of physiologically relevant curvatures, cause a substantial change in the pressure profile but it also significantly modifies the stress distribution in response to force application. Understanding these stress variations in regions of high local bending is essential for a complete understanding of the effects of curvature on MS channels. PMID:26861405
Magnetophoretic Induction of Root Curvature
NASA Technical Reports Server (NTRS)
Hasenstein, Karl H.
1997-01-01
The last year of the grant period concerned the consolidation of previous experiments to ascertain that the theoretical premise apply not just to root but also to shoots. In addition, we verified that high gradient magnetic fields do not interfere with regular cellular activities. Previous results have established that: (1) intracellular magnetophoresis is possible; and (2) HGMF lead to root curvature. In order to investigate whether HGMF affect the assembly and/or organization of structural proteins, we examined the arrangement of microtubules in roots exposed to HGMF. The cytoskeletal investigations were performed with fomaldehyde-fixed, nonembedded tissue segments that were cut with a vibratome. Microtubules (MTs) were stained with rat anti-yeast tubulin (YOL 1/34) and DTAF-labeled antibody against rat IgG. Microfilaments (MFs) were visualized by incubation in rhodamine-labeled phalloidin. The distribution and arrangement of both components of the cytoskeleton were examined with a confocal microscope. Measurements of growth rates and graviresponse were done using a video-digitizer. Since HGMF repel diamagnetic substances including starch-filled amyloplasts and most The second aspect of the work includes studies of the effect of cytoskeletal inhibitors on MTs and MFs. The analysis of the effect of micotubular inhibitors on the auxin transport in roots showed that there is very little effect of MT-depolymerizing or stabilizing drugs on auxin transport. This is in line with observations that application of such drugs is not immediately affecting the graviresponsiveness of roots.
Spontaneous Curvature of Polymer Brushes
NASA Astrophysics Data System (ADS)
Sheiko, Sergei; da Silva, Marcelo; Shirvaniants, David; Rodrigues, Carlos; Beers, Kathryn; Matyjaszewski, Krzysztof; Potemkin, Igor; Moeller, Martin
2003-03-01
Experimental studies of cylindrical brushes on surfaces revealed peculiar shape of brush molecules with a curved backbone. According to scaling analysis, spontaneous bending of the backbone can be driven by entropic elasticity of the side chains: smaller extension of the chains is attained due to their asymmetric distribution with respect to the backbone. An equilibrium, i.e. spontaneous curvature results from the balance of the elasticity of the side chains and the elasticity of the interface. The curvature is predicted to increase with the side chain length. The system is of general interest because cylindrical brushes confined to a flat surface represent a two-dimensional cross-section of a planar brush grafted on both sides. Here we present systematic studies of cylindrical brushes with different length of the side chains. The curvature of cylindrical brushes confined to a flat substrate was investigated by atomic force microscopy. The method allowed visualization of individual molecules and quantitative analysis of their conformation. In agreement with theory, adsorbed brushes demonstrated spontaneous curvature, however the curvature was shown to decrease with the side chain length.
Do adult men with untreated ventral penile curvature have adverse outcomes?
Menon, Vani; Breyer, Benjamin; Copp, Hillary L.; Baskin, Laurence; Disandro, Michael; Schlomer, Bruce J.
2016-01-01
Summary Introduction Congenital ventral penile curvature without hypospadias is often treated surgically in childhood. The history of untreated ventral curvature is unknown. Objective This study’s aim was to examine the association of untreated ventral penile curvature with various sexual and psychosexual outcomes. Study design An electronic survey was advertised to men older than 18 years on Facebook. Men with possible ventral penile curvature identified themselves by choosing sketches that most closely represented their anatomy. Outcomes assessed included: Sexual Health Inventory for Men, difficulty of intercourse because of curvature, International Prostate Symptom Score, Penile Perception Score, psychosexual milestones, paternity, infertility, sitting to urinate, and the CDC HRQOL-4 module. Results Among participants, 81 out of 684 men (11.8%) reported untreated ventral penile curvature. Participants with self-reported curvature noted more difficulty with intercourse because of curvature (4.5 vs 4.9, p < 0.001), more unhealthy mental days (8.6 vs 6.2, p = 0.02), and increased dissatisfaction with penile self-perception compared with men without reported curvature (8.6 vs 9.5, p < 0.001). Discussion Men with possible untreated ventral curvature reported worse penile perception scores, more mentally unhealthy days, and increased difficulty with intercourse secondary to curvature compared with men without curvature. A limitation to this study is selection bias; responses collected were self-reported from survey volunteers. Additionally, the question identifying ventral penile curvature is not validated but performed well in pretesting. Most questions were from validated surveys, but some were modeled after validated surveys and/or contained high face validity types of questions. Conclusion Men with possible untreated ventral penile curvature reported more dissatisfaction with penile appearance, increased difficulty with intercourse, and more unhealthy mental
Geometry-specific scaling of detonation parameters from front curvature
Jackson, Scott I; Short, Mark
2011-01-20
It has previously been asserted that classical detonation curvature theory predicts that the critical diameter and the diameter-effect curve of a cylindrical high-explosive charge should scale with twice the thickness of an analogous two-dimensional explosive slab. The varied agreement of experimental results with this expectation have led some to question the ability of curvature-based concepts to predict detonation propagation in non-ideal explosives. This study addresses such claims by showing that the expected scaling relationship (hereafter referred to d = 2w) is not consistent with curvature-based Detonation Shock Dynamics (DSD) theory.
LPG-based sensor for curvature and vibration
NASA Astrophysics Data System (ADS)
Nascimento, I. M.; Chesini, G.; Baptista, J. M.; Cordeiro, Cristiano M. B.; Jorge, P. A. S.
2016-05-01
A long-period grating (LPG) written on a standard single mode fiber is investigated as a curvature and vibration sensor. It is demonstrated a high sensitivity to applied curvature and the possibility to monitor vibration in a wide range of frequencies from 30 Hz to 2000 Hz. The system was tested using an intensity based interrogation scheme with the LPG sensor operating in the curvature regime. Results have shown a reproducible frequency discrimination in the 30 Hz to 2000 Hz, with resolutions between 11 mHz and 913 mHz. Frequency retrieval could be performed independent of temperature up to 86 °C.
Curvature generation in nematic surfaces
NASA Astrophysics Data System (ADS)
Mostajeran, Cyrus
2015-06-01
In recent years there has been a growing interest in the study of shape formation using modern responsive materials that can be preprogrammed to undergo spatially inhomogeneous local deformations. In particular, nematic liquid crystalline solids offer exciting possibilities in this context. Considerable recent progress has been made in achieving a variety of shape transitions in thin sheets of nematic solids by engineering isolated points of concentrated Gaussian curvature using topological defects in the nematic director field across textured surfaces. In this paper, we consider ways of achieving shape transitions in thin sheets of nematic glass by generation of nonlocalized Gaussian curvature in the absence of topological defects in the director field. We show how one can blueprint any desired Gaussian curvature in a thin nematic sheet by controlling the nematic alignment angle across the surface and highlight specific patterns which present feasible initial targets for experimental verification of the theory.
Intrinsically disordered proteins drive membrane curvature
Busch, David J.; Houser, Justin R.; Hayden, Carl C.; Sherman, Michael B.; Lafer, Eileen M.; Stachowiak, Jeanne C.
2015-01-01
Assembly of highly curved membrane structures is essential to cellular physiology. The prevailing view has been that proteins with curvature-promoting structural motifs, such as wedge-like amphipathic helices and crescent-shaped BAR domains, are required for bending membranes. Here we report that intrinsically disordered domains of the endocytic adaptor proteins, Epsin1 and AP180 are highly potent drivers of membrane curvature. This result is unexpected since intrinsically disordered domains lack a well-defined three-dimensional structure. However, in vitro measurements of membrane curvature and protein diffusivity demonstrate that the large hydrodynamic radii of these domains generate steric pressure that drives membrane bending. When disordered adaptor domains are expressed as transmembrane cargo in mammalian cells, they are excluded from clathrin-coated pits. We propose that a balance of steric pressure on the two surfaces of the membrane drives this exclusion. These results provide quantitative evidence for the influence of steric pressure on the content and assembly of curved cellular membrane structures. PMID:26204806
Intrinsically disordered proteins drive membrane curvature
NASA Astrophysics Data System (ADS)
Busch, David J.; Houser, Justin R.; Hayden, Carl C.; Sherman, Michael B.; Lafer, Eileen M.; Stachowiak, Jeanne C.
2015-07-01
Assembly of highly curved membrane structures is essential to cellular physiology. The prevailing view has been that proteins with curvature-promoting structural motifs, such as wedge-like amphipathic helices and crescent-shaped BAR domains, are required for bending membranes. Here we report that intrinsically disordered domains of the endocytic adaptor proteins, Epsin1 and AP180 are highly potent drivers of membrane curvature. This result is unexpected since intrinsically disordered domains lack a well-defined three-dimensional structure. However, in vitro measurements of membrane curvature and protein diffusivity demonstrate that the large hydrodynamic radii of these domains generate steric pressure that drives membrane bending. When disordered adaptor domains are expressed as transmembrane cargo in mammalian cells, they are excluded from clathrin-coated pits. We propose that a balance of steric pressure on the two surfaces of the membrane drives this exclusion. These results provide quantitative evidence for the influence of steric pressure on the content and assembly of curved cellular membrane structures.
MARCKS-ED Peptide as a Curvature and Lipid Sensor
Morton, Leslie A.; Yang, Hengwen; Saludes, Jonel P.; Fiorini, Zeno; Beninson, Lida; Chapman, Edwin R.; Fleshner, Monika; Xue, Ding; Yin, Hang
2012-01-01
Membrane curvature and lipid composition regulate important biological processes within a cell. Currently, several proteins have been reported to sense and/or induce membrane curvatures, e.g. Synaptotagmin-1 and Amphiphysin. However, the large protein scaffold of these curvature sensors limits their applications in complex biological systems. Our interest focuses on identifying and designing peptides that can sense membrane curvature based on established elements observed in natural curvature-sensing proteins. Membrane curvature remodeling also depends on their lipid composition, suggesting strategies to specifically target membrane shape and lipid components simultaneously. We have successfully identified a 25-mer peptide, MARCKS-ED, based on the effector domain sequence of the intracellular membrane protein myristoylated alanine-rich C-kinase substrate that can recognize PS with preferences for highly curved vesicles in a sequence specific manner. These studies further contribute to the understanding of how proteins and peptides sense membrane curvature, as well as provide potential probes for membrane shape and lipid composition. PMID:23075500
Cosmic strings with curvature corrections
NASA Astrophysics Data System (ADS)
Boisseau, Bruno; Letelier, Patricio S.
1992-08-01
A generic model of string described by a Lagrangian density that depends on the extrinsic curvature of the string worldsheet is studied. Using a system of coordinates adapted to the string world sheet the equation of motion and the energy-momentum tensor are derived for strings evolving in curved spacetime. We find that the curvature corrections may change the relation between the string energy density and the tension. It can also introduce heat propagation along the string. We also find for the Polyakov as well as Nambu strings with a topological term that the open string end points can travel with a speed less than the velocity of light.
NASA Astrophysics Data System (ADS)
Torgoev, Almaz; Havenith, Hans-Balder
2016-01-01
A 2D elasto-dynamic modelling of the pure topographic seismic response is performed for six models with a total length of around 23.0 km. These models are reconstructed from the real topographic settings of the landslide-prone slopes situated in the Mailuu-Suu River Valley, Southern Kyrgyzstan. The main studied parameter is the Arias Intensity (Ia, m/sec), which is applied in the GIS-based Newmark method to regionally map the seismically-induced landslide susceptibility. This method maps the Ia values via empirical attenuation laws and our studies investigate a potential to include topographic input into them. Numerical studies analyse several signals with varying shape and changing central frequency values. All tests demonstrate that the spectral amplification patterns directly affect the amplification of the Ia values. These results let to link the 2D distribution of the topographically amplified Ia values with the parameter called as smoothed curvature. The amplification values for the low-frequency signals are better correlated with the curvature smoothed over larger spatial extent, while those values for the high-frequency signals are more linked to the curvature with smaller smoothing extent. The best predictions are provided by the curvature smoothed over the extent calculated according to Geli's law. The sample equations predicting the Ia amplification based on the smoothed curvature are presented for the sinusoid-shape input signals. These laws cannot be directly implemented in the regional Newmark method, as 3D amplification of the Ia values addresses more problem complexities which are not studied here. Nevertheless, our 2D results prepare the theoretical framework which can potentially be applied to the 3D domain and, therefore, represent a robust basis for these future research targets.
NASA Astrophysics Data System (ADS)
Torgoev, Almaz; Havenith, Hans-Balder
2016-07-01
A 2D elasto-dynamic modelling of the pure topographic seismic response is performed for six models with a total length of around 23.0 km. These models are reconstructed from the real topographic settings of the landslide-prone slopes situated in the Mailuu-Suu River Valley, Southern Kyrgyzstan. The main studied parameter is the Arias Intensity (Ia, m/sec), which is applied in the GIS-based Newmark method to regionally map the seismically-induced landslide susceptibility. This method maps the Ia values via empirical attenuation laws and our studies investigate a potential to include topographic input into them. Numerical studies analyse several signals with varying shape and changing central frequency values. All tests demonstrate that the spectral amplification patterns directly affect the amplification of the Ia values. These results let to link the 2D distribution of the topographically amplified Ia values with the parameter called as smoothed curvature. The amplification values for the low-frequency signals are better correlated with the curvature smoothed over larger spatial extent, while those values for the high-frequency signals are more linked to the curvature with smaller smoothing extent. The best predictions are provided by the curvature smoothed over the extent calculated according to Geli's law. The sample equations predicting the Ia amplification based on the smoothed curvature are presented for the sinusoid-shape input signals. These laws cannot be directly implemented in the regional Newmark method, as 3D amplification of the Ia values addresses more problem complexities which are not studied here. Nevertheless, our 2D results prepare the theoretical framework which can potentially be applied to the 3D domain and, therefore, represent a robust basis for these future research targets.
Amplification of curvature perturbations in cyclic cosmology
Zhang Jun; Liu Zhiguo; Piao Yunsong
2010-12-15
We analytically and numerically show that through the cycles with nonsingular bounce, the amplitude of curvature perturbation on a large scale will be amplified and the power spectrum will redden. In some sense, this amplification will eventually destroy the homogeneity of the background, which will lead to the ultimate end of cycles of the global universe. We argue that for the model with increasing cycles, it might be possible that a fissiparous multiverse will emerge after one or several cycles, in which the cycles will continue only at corresponding local regions.
NASA Astrophysics Data System (ADS)
Ma, Shuang; Yi, Shengzhen; Chen, Shenghao; Wang, Zhanshan
2014-11-01
Monochromatic energy multilayer Kirkpatrick-Baez microscope is one of key diagnostic tools for researches on inertial confinement fusion. It is composed by two orthogonal concave spherical mirrors with small curvature and aperture, and produce the image of an object by collecting X-rays in each orthogonal direction, independently. Accurate measurement of radius of curvature of concave spherical mirrors is very important to achieve its design optical properties including imaging quality, optical throughput and energy resolution. However, it is difficult to measure the radius of curvature of spherical optical surfaces with small curvature and aperture by conventional methods, for the produced reflective intensity of glass is too low to correctly test. In this paper, we propose an improved measuring method of optical profiler to accomplish accurate measurement of radius of curvature of spherical optical surfaces with small curvature and aperture used in the monochromatic energy multilayer Kirkpatrick-Baez microscope. Firstly, we use a standard super-smooth optical flat to calibrate reference mirror before each experiment. Following, deviation of central position between measurement area and interference pattern is corrected by the theory of Newton's rings, and the zero-order fringe position is derived from the principle of interference in which surface roughness has minimum values in the position of zero light path difference. Measured results by optical profiler show the low relative errors and high repeatability. Eventually, an imaging experiment of monochromatic energy multilayer Kirkpatrick-Baez microscope determines the measurement accuracy of radius of curvature.
Femoral condyle curvature is correlated with knee walking kinematics in ungulates.
Sylvester, Adam D
2015-12-01
The knee has been the focus of many studies linking mammalian postcranial form with locomotor behaviors and animal ecology. A more difficult task has been linking joint morphology with joint kinematics during locomotor tasks. Joint curvature represents one opportunity to link postcranial morphology with walking kinematics because joint curvature develops in response to mechanical loading. As an initial examination of mammalian knee joint curvature, the curvature of the medial femoral condyle was measured on femora representing 11 ungulate species. The position of a region of low curvature was measured using a metric termed the "angle to low curvature". This low-curvature region is important because it provides the greatest contact area between femoral and tibial condyles. Kinematic knee angles during walking were derived from the literature and kinematic knee angles across the gait cycle were correlated with angle to low curvature values. The highest correlation between kinematic knee angle and the angle to low curvature metric occurred at 20% of the walking gait cycle. This early portion of the walking gait cycle is associated with a peak in the vertical ground reaction force for some mammals. The chondral modeling theory predicts that frequent and heavy loading of particular regions of a joint surface during ontogeny will result in these regions being flatter than the surrounding joint surface. The locations of flatter regions of the femoral condyles of ungulates, and their association with knee angles used during the early stance phase of walking provides support for the chondral modeling theory. PMID:26414648
The Induction of Negative Curvature as a Mechanism of Cell Toxicity by Amyloidogenic Peptides
Smith, Pieter E. S.; Brender, Jeffrey R.; Ramamoorthy, Ayyalusamy
2009-01-01
The death of insulin-producing β-cells is a key step in the pathogenesis of type 2 diabetes. The amyloidogenic peptide Islet Amyloid Polypeptide (IAPP, also known as amylin) has been shown to disrupt β-cell membranes leading to β-cell death. Despite the strong evidence linking IAPP to the destruction of β-cell membrane integrity and cell death, the mechanism of IAPP toxicity is poorly understood. In particular, the effect of IAPP on the bilayer structure has largely been uncharacterized. In this study, we have determined the effect of the amyloidogenic and toxic hIAPP1-37 peptide and the non-toxic and non-amyloidogenic rIAPP1-37 peptide on membranes by a combination of DSC and solid-state NMR spectroscopy. We also characterized the toxic but largely non-amyloidogenic rIAPP1-19 and hIAPP1-19 fragments. DSC shows that both amyloidogenic (hIAPP1-37) and largely non-amyloidogenic (hIAPP1-19 and rIAPP1-19) toxic versions of the peptide strongly favor the formation of negative curvature in lipid bilayers, while the non-toxic full-length rat IAPP1-37 peptide does not. This result was confirmed by solid-state NMR spectroscopy which shows that in bicelles composed of regions of high curvature and low curvature, non-toxic rIAPP1-37 binds to the regions of low curvature while toxic rIAPP1-19 binds to regions of high curvature. Similarly, solid-state NMR spectroscopy shows that the toxic rIAPP1-19 peptide significantly disrupts the lipid bilayer structure, whereas the non-toxic rIAPP1-37 does not have a significant effect. These results indicate IAPP may induce the formation of pores by the induction of excess membrane curvature and can be used to guide the design of compounds that can prevent the cell-toxicity of IAPP. This mechanism may be important to understand the toxicity of other amyloidogenic proteins. Our solid-state NMR results also demonstrate the possibility of using bicelles to measure the affinity of biomolecules for negatively or positively curved regions of
Nanoscale Membrane Curvature detected by Polarized Localization Microscopy
NASA Astrophysics Data System (ADS)
Kelly, Christopher; Maarouf, Abir; Woodward, Xinxin
Nanoscale membrane curvature is a necessary component of countless cellular processes. Here we present Polarized Localization Microscopy (PLM), a super-resolution optical imaging technique that enables the detection of nanoscale membrane curvature with order-of-magnitude improvements over comparable optical techniques. PLM combines the advantages of polarized total internal reflection fluorescence microscopy and fluorescence localization microscopy to reveal single-fluorophore locations and orientations without reducing localization precision by point spread function manipulation. PLM resolved nanoscale membrane curvature of a supported lipid bilayer draped over polystyrene nanoparticles on a glass coverslip, thus creating a model membrane with coexisting flat and curved regions and membrane radii of curvature as small as 20 nm. Further, PLM provides single-molecule trajectories and the aggregation of curvature-inducing proteins with super-resolution to reveal the correlated effects of membrane curvature, dynamics, and molecular sorting. For example, cholera toxin subunit B has been observed to induce nanoscale membrane budding and concentrate at the bud neck. PLM reveals a previously hidden and critical information of membrane topology.
Monomeric Synucleins Generate Membrane Curvature*
Westphal, Christopher H.; Chandra, Sreeganga S.
2013-01-01
Synucleins are a family of presynaptic membrane binding proteins. α-Synuclein, the principal member of this family, is mutated in familial Parkinson disease. To gain insight into the molecular functions of synucleins, we performed an unbiased proteomic screen and identified synaptic protein changes in αβγ-synuclein knock-out brains. We observed increases in the levels of select membrane curvature sensing/generating proteins. One of the most prominent changes was for the N-BAR protein endophilin A1. Here we demonstrate that the levels of synucleins and endophilin A1 are reciprocally regulated and that they are functionally related. We show that all synucleins can robustly generate membrane curvature similar to endophilins. However, only monomeric but not tetrameric α-synuclein can bend membranes. Further, A30P α-synuclein, a Parkinson disease mutant that disrupts protein folding, is also deficient in this activity. This suggests that synucleins generate membrane curvature through the asymmetric insertion of their N-terminal amphipathic helix. Based on our findings, we propose to include synucleins in the class of amphipathic helix-containing proteins that sense and generate membrane curvature. These results advance our understanding of the physiological function of synucleins. PMID:23184946
Effects of the curvature of a lava channel on velocity and stress fields
NASA Astrophysics Data System (ADS)
Valerio, Antonella; Tallarico, Andrea; Dragoni, Michele
2010-05-01
Bends in lava flows due to local variations in topography are commonly observed in volcanic fields. The curvature of a channel affects the flow surface morphology, as described in literature by Greeley (1971) and Peterson (1994). Where channels make an especially sharp bend, crust plates break and are incorporated within the flow by remelting. In some places, they jam together welding to the sides of the channel and forming a stable roof. We propose a model to explain the effects of the curvature of a channel on velocity, shear stress and formation of solid crust at the surface. Lava is described as a Newtonian, homogeneous, isotropic and incompressible fluid. The steady-state solution of the Navier-Stokes equation is found for a unidirectional flow, in cylindrical polar coordinates, neglecting the gradient of pressure and assuming a dependence of velocity on the radial coordinate only. The flow levees are described as arcs of concentric circumferences, with their centres in the origin of the reference frame. The equation is solved using non-slip boundary conditions at the levees. From the constitutive equation of a Newtonian incompressible fluid we obtain the nonvanishing component of the shear stress. As a consequence of the curvature of the channel, velocity and shear stress show an asymmetric behaviour in respect to the centre of the channel. The gradient of velocity and the shear stress reach larger values close to the levee with the higher curvature. Heat radiation and convection into the atmosphere are considered as the main cooling processes. Solid platforms form at the flow surface during cooling. Crust plates are laterally confined by the shear regions with high stress values. The model analyses the effects of the curvature of a channel on the development and shape of surface solid plates. The dimension and shape of plates are controlled by the competition between the shear stress and crust yield strength, and the degree of crust coverage of the channel
Holonomy Attractor Connecting Spaces of Different Curvature Responsible for ``Anomalies''
NASA Astrophysics Data System (ADS)
Binder, Bernd
2009-03-01
In this lecture paper we derive Magic Angle Precession (MAP) from first geometric principles. MAP can arise in situations, where precession is multiply related to spin, linearly by time or distance (dynamic phase, rolling, Gauss law) and transcendentally by the holonomy loop path (geometric phase). With linear spin-precession coupling, gyroscopes can be spun up and down to very high frequencies via low frequency holonomy control induced by external accelerations, which provides for extreme coupling strengths or "anomalies" that can be tested by the powerball or gyrotwister device. Geometrically, a gyroscopic manifold with spherical metric is tangentially aligned to a precession wave channel with conic or hyperbolic metric (like the relativistic Thomas precession). Transporting triangular spin/precession vector relations across the tangential boundary of contact with SO(3) Lorentz symmetry, we get extreme vector currents near the attractor fixed points in precession phase space, where spin currents remain intact while crossing the contact boundaries between regions of different curvature signature (-1, 0, +1). The problem can be geometrically solved by considering a curvature invariant triangular condition, which holds on surfaces with different curvature that are in contact and locally parallel. In this case two out of three angles are identical, whereas the third angle is different due to holonomy. If we require that the side length ratio corresponding to these angles are invariant we get a geodesic chaotic attractor, which is a cosine map cos(x)˜Mx in parameter space providing for fixed points, limit cycle bifurcations, and singularities. The situation could be quite natural and common in the context of vector currents in curved spacetime and gauge theories. MAP could even be part of the electromagnetic interaction, where the electric charge is the geometric U(1) precession spin current and gauge potential with magnetic effects given by extra rotations under the
Curvature and bow of bulk GaN substrates
NASA Astrophysics Data System (ADS)
Foronda, Humberto M.; Romanov, Alexey E.; Young, Erin C.; Roberston, Christian A.; Beltz, Glenn E.; Speck, James S.
2016-07-01
We investigate the bow of free standing (0001) oriented hydride vapor phase epitaxy grown GaN substrates and demonstrate that their curvature is consistent with a compressive to tensile stress gradient (bottom to top) present in the substrates. The origin of the stress gradient and the curvature is attributed to the correlated inclination of edge threading dislocation (TD) lines away from the [0001] direction. A model is proposed and a relation is derived for bulk GaN substrate curvature dependence on the inclination angle and the density of TDs. The model is used to analyze the curvature for commercially available GaN substrates as determined by high resolution x-ray diffraction. The results show a close correlation between the experimentally determined parameters and those predicted from theoretical model.
Space Curvature and the "Heavy Banana 'Paradox.'"
ERIC Educational Resources Information Center
Gruber, Ronald P.; And Others
1991-01-01
Two ways to visually enhance the concept of space curvature are described. Viewing space curvature as a meterstick contraction and the heavy banana "paradox" are discussed. The meterstick contraction is mathematically explained. (KR)
Curvature of co-links uncovers hidden thematic layers in the World Wide Web.
Eckmann, Jean-Pierre; Moses, Elisha
2002-04-30
Beyond the information stored in pages of the World Wide Web, novel types of "meta-information" are created when pages connect to each other. Such meta-information is a collective effect of independent agents writing and linking pages, hidden from the casual user. Accessing it and understanding the interrelation between connectivity and content in the World Wide Web is a challenging problem [Botafogo, R. A. & Shneiderman, B. (1991) in Proceedings of Hypertext (Assoc. Comput. Mach., New York), pp. 63-77 and Albert, R. & Barabási, A.-L. (2002) Rev. Mod. Phys. 74, 47-97]. We demonstrate here how thematic relationships can be located precisely by looking only at the graph of hyperlinks, gleaning content and context from the Web without having to read what is in the pages. We begin by noting that reciprocal links (co-links) between pages signal a mutual recognition of authors and then focus on triangles containing such links, because triangles indicate a transitive relation. The importance of triangles is quantified by the clustering coefficient [Watts, D. J. & Strogatz, S. H. (1999) Nature (London) 393, 440-442], which we interpret as a curvature [Bridson, M. R. & Haefliger, A. (1999) Metric Spaces of Non-Positive Curvature (Springer, Berlin)]. This curvature defines a World Wide Web landscape whose connected regions of high curvature characterize a common topic. We show experimentally that reciprocity and curvature, when combined, accurately capture this meta-information for a wide variety of topics. As an example of future directions we analyze the neural network of Caenorhabditis elegans, using the same methods. PMID:11972019
Spacetime Curvature and Higgs Stability after Inflation.
Herranen, M; Markkanen, T; Nurmi, S; Rajantie, A
2015-12-11
We investigate the dynamics of the Higgs field at the end of inflation in the minimal scenario consisting of an inflaton field coupled to the standard model only through the nonminimal gravitational coupling ξ of the Higgs field. Such a coupling is required by renormalization of the standard model in curved space, and in the current scenario also by vacuum stability during high-scale inflation. We find that for ξ≳1, rapidly changing spacetime curvature at the end of inflation leads to significant production of Higgs particles, potentially triggering a transition to a negative-energy Planck scale vacuum state and causing an immediate collapse of the Universe. PMID:26705621
Overriding plate thickness control on subducting slab curvature
NASA Astrophysics Data System (ADS)
Holt, A.; Buffett, B. A.; Becker, T. W.
2014-12-01
The curvature of subducting lithosphere controls deformation due to bending at the trench, which results in a force that dissipates gravitational potential energy and may affect seismic coupling. We use 2-D, thermo-mechanical subduction models to explore the dependence of the radius of curvature on the thickness of the subducting and overriding plates for models with both viscous and effectively plastic lithospheric rheologies. Such a plastic rheology has been shown to reproduce the bending stresses/moment computed using a kinematic strain rate description and a laboratory derived composite rheology. Laboratory and numerical models show that the bending geometry of subducting slabs with a viscous rheology is strongly dependent on slab thickness; thicker plates have a larger radius of curvature. However, the curvature of subducting plates on Earth, illuminated by the distribution of earthquake hypocenters, shows little to no dependence on the plate thickness or age. Such an observation is instead compatible with plates that have a plastic rheology. Indeed, our numerical models show that the radius of curvature of viscous plates has a stronger dependence on subducting plate thickness than in equivalent plastic models. In viscous plates, the bending moment produces a torque, which balances the torque exerted by buoyancy. However, for the plastic plate case the bending moment saturates at a maximum value and so cannot balance the gravitational torque. The saturation of bending moment means that, (a) the radius of curvature of the bending region is not constrained by this torque balance, and, (b) other forces are required to balance the gravitational torque. We explore the role that the overriding plate could play in controlling the subducting plate curvature in plastic plate models where the bending stresses have saturated. For such plates, we find that increasing the thickness of the overriding plate causes the radius of curvature to increase. The same correlation is
Clinical workflow for spinal curvature measurement with portable ultrasound
NASA Astrophysics Data System (ADS)
Tabanfar, Reza; Yan, Christina; Kempston, Michael; Borschneck, Daniel; Ungi, Tamas; Fichtinger, Gabor
2016-03-01
PURPOSE: Spinal curvature monitoring is essential in making treatment decisions in scoliosis. Monitoring entails radiographic examinations, however repeated ionizing radiation exposure has been shown to increase cancer risk. Ultrasound does not emit ionizing radiation and is safer for spinal curvature monitoring. We investigated a clinical sonography protocol and challenges associated with position-tracked ultrasound in spinal curvature measurement in scoliosis. METHODS: Transverse processes were landmarked along each vertebra using tracked ultrasound snapshots. The transverse process angle was used to determine the orientation of each vertebra. We tested our methodology on five patients in a local pediatric scoliosis clinic, comparing ultrasound to radiographic curvature measurements. RESULTS: Despite strong correlation between radiographic and ultrasound curvature angles in phantom studies, we encountered new challenges in the clinical setting. Our main challenge was differentiating transverse processes from ribs and other structures during landmarking. We observed up to 13° angle variability for a single vertebra and a 9.85° +/- 10.81° difference between ultrasound and radiographic Cobb angles for thoracic curvatures. Additionally, we were unable to visualize anatomical landmarks in the lumbar region where soft tissue depth was 25-35mm. In volunteers with large Cobb angles (greater than 40° thoracic and 60° lumbar), we observed spinal protrusions resulting in incomplete probe-skin contact and partial ultrasound images not suitable for landmarking. CONCLUSION: Spinal curvature measurement using tracked ultrasound is viable on phantom spine models. In the clinic, new challenges were encountered which must be resolved before a universal sonography protocol can be developed.
Nonlinear Sorting, Curvature Generation, and Crowding of Endophilin N-BAR on Tubular Membranes
Zhu, Chen; Das, Sovan L.; Baumgart, Tobias
2012-01-01
The curvature of biological membranes is controlled by membrane-bound proteins. For example, during endocytosis, the sorting of membrane components, vesicle budding, and fission from the plasma membrane are mediated by adaptor and accessory proteins. Endophilin is a peripherally binding membrane protein that functions as an endocytic accessory protein. Endophilin's membrane tubulation capacity is well known. However, to understand the thermodynamic and mechanical aspects of endophilin function, experimental measurements need to be compared to quantitative theoretical models. We present measurements of curvature sorting and curvature generation of the endophilin A1 N-BAR domain on tubular membranes pulled from giant unilamellar vesicles. At low concentration, endophilin functions primarily as a membrane curvature sensor; at high concentrations, it also generates curvature. We determine the spontaneous curvature induced by endophilin and observe sigmoidal curvature/composition coupling isotherms that saturate at high membrane tensions and protein solution concentrations. The observation of saturation is supported by a strong dependence of lateral diffusion coefficients on protein density on the tether membrane. We develop a nonlinear curvature/composition coupling model that captures our experimental observations. Our model predicts a curvature-induced phase transition among two states with varying protein density and membrane curvature. This transition could act as a switch during endocytosis. PMID:22768939
Machine Learning Models for Detection of Regions of High Model Form Uncertainty in RANS
NASA Astrophysics Data System (ADS)
Ling, Julia; Templeton, Jeremy
2015-11-01
Reynolds Averaged Navier Stokes (RANS) models are widely used because of their computational efficiency and ease-of-implementation. However, because they rely on inexact turbulence closures, they suffer from significant model form uncertainty in many flows. Many RANS models make use of the Boussinesq hypothesis, which assumes a non-negative, scalar eddy viscosity that provides a linear relation between the Reynolds stresses and the mean strain rate. In many flows of engineering relevance, this eddy viscosity assumption is violated, leading to inaccuracies in the RANS predictions. For example, in near wall regions, the Boussinesq hypothesis fails to capture the correct Reynolds stress anisotropy. In regions of flow curvature, the linear relation between Reynolds stresses and mean strain rate may be inaccurate. This model form uncertainty cannot be quantified by simply varying the model parameters, as it is rooted in the model structure itself. Machine learning models were developed to detect regions of high model form uncertainty. These machine learning models consisted of binary classifiers that predicted, on a point-by-point basis, whether or not key RANS assumptions were violated. These classifiers were trained and evaluated for their sensitivity, specificity, and generalizability on a database of canonical flows.
Detonation Front Curvatures and Detonation Rates
NASA Astrophysics Data System (ADS)
Lauderbach, Lisa M.; Lorenz, K. Thomas; Lee, Edward L.; Souers, P. Clark
2015-06-01
We have normalized the LLNL library of detonation front curvatures by dividing lags by the edge lag and radii by the edge radius. We then fit the normalized data to the equation L = AR2 + BR8, where L is the normalized lag and R is the normalized radius. We attribute the quadratic term to thermal processes and the 8th-power term to shock processes. We compare the % of the quadratic term J at the edge with detonation rates obtained from the size effect. One class of results is made up of fine-grained, uniform explosives with large lags, where a low detonation rate leads to a high J and vice versa. This provides a rough way of estimating unknown rates if the unknown explosive is of high quality. The other, equally-large class contains rough-grained materials, often with small lags and small radii. These have curves that do not fit the equation but superfically often look quadratic. Some HMX and PETN curvatures even show a ``sombrero'' effect. Code models show that density differences of 0.03 g/cc in ram-pressed parts can cause pseudo-quadratic curves and even sombreros. Modeling is used to illustrate J at the lowest and highest possible detonation rates. This work performed under the auspices of the U. S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344.
SLED phenomenology: curvature vs. volume
NASA Astrophysics Data System (ADS)
Niedermann, Florian; Schneider, Robert
2016-03-01
We assess the question whether the SLED (Supersymmetric Large Extra Dimensions) model admits phenomenologically viable solutions with 4D maximal symmetry. We take into account a finite brane width and a scale invariance (SI) breaking dilaton-brane coupling, both of which should be included in a realistic setup. Provided that the brane tension and the microscopic size of the brane take generic values set by the fundamental bulk Planck scale, we find that either the 4D curvature or the size of the extra dimensions is unacceptably large. Since this result is independent of the dilaton-brane couplings, it provides the biggest challenge to the SLED program.
NASA Astrophysics Data System (ADS)
Dass, Sumit; Narayan Dash, Jitendra; Jha, Rajan
2016-03-01
We propose a highly sensitive curvature sensor based on cascaded single mode fiber (SMF) tapers with a microcavity. The microcavity is created by splicing a small piece of hollow core photonic crystal fiber (HCPCF) at the end of an SMF to obtain a sharp interference pattern. Experimental results show that two SMF tapers enhance the curvature sensitivity of the system and by changing the tapering parameters of the second taper, the curvature sensitivity of the system can be tailored, together with the fringe contrast of the interference pattern. A maximum curvature sensitivity of 10.4 dB/m-1 is observed in the curvature range 0 to 1 m-1 for a second taper diameter of 18 μm. The sensing setup is highly stable and shows very low temperature sensitivity. As the interrogation is intensity based, a low cost optical power meter can be utilized to determine the curvature.
Long-time behavior of material-surface curvature in isotropic turbulence
NASA Technical Reports Server (NTRS)
Girimaji, S. S.
1992-01-01
The behavior at large times of the curvature of material elements in turbulence is investigated using Lagrangian velocity-gradient time series obtained from direct numerical simulations of isotropic turbulence. The main objectives are: to study the asymptotic behavior of the pdf curvature as a function of initial curvature and shape; and to establish whether the curvature of an initially plane material element goes to a stationary probability distribution. The evidence available in the literature about the asymptotic curvature-pdf of initially flat surfaces is ambiguous, and the conjecture is that it is quasi-stationary. In this work several material-element ensembles of different initial curvatures and shapes are studied. It is found that, at long times the moments of the logarithm of curvature are independent of the initial pdf of curvature. This, it is argued, supports the view that the curvature attains a stationary distribution at long times. It is also shown that, irrespective of initial shape or curvature, the shape of any material element at long times is cylindrical with a high probability.
Membrane curvature sensing by the C-terminal domain of complexin
NASA Astrophysics Data System (ADS)
Snead, David; Wragg, Rachel T.; Dittman, Jeremy S.; Eliezer, David
2014-09-01
Complexin functions at presynaptic nerve terminals to inhibit spontaneous SNARE-mediated synaptic vesicle (SV) exocytosis, while enhancing stimulated neurotransmitter release. The C-terminal domain (CTD) of complexin is essential for its inhibitory function and has been implicated in localizing complexin to SVs via direct membrane interactions. Here we show that complexin’s CTD is highly sensitive to membrane curvature, which it senses via tandem motifs, a C-terminal motif containing a mix of bulky hydrophobic and positively charged residues, and an adjacent amphipathic region that can bind membranes in either a disordered or a helical conformation. Helix formation requires membrane packing defects found on highly curved membrane surfaces. Mutations that disrupt helix formation without disrupting membrane binding compromise complexin’s inhibitory function in vivo. Thus, this membrane curvature-dependent conformational transition, combined with curvature-sensitive binding by the adjacent C-terminal motif, constitute a novel mechanism for activating complexin’s inhibitory function on the surface of SVs.
An Experimental Study of Laminarization Induced by Acceleration and Curvature
NASA Astrophysics Data System (ADS)
Jackson, R. Brian
The Generation IV Very High Temperature Reactor (VHTR) design is being actively studied in various countries for application due to its inherent passive safe design, higher thermal efficiencies, and proposed capability of providing high temperature process heat. The pebble bed core is one of two core designs used in gas reactors. In the pebble bed core there are mechanisms present which can cause the flow to laminarize, thus reducing its heat transfer effectiveness. Wind tunnel experiments were conducted using Particle Image Velocimetry (PIV) to investigate boundary layer laminarization due to flow acceleration and convex curvature effects. The flow was subject to acceleration and curvature both separately and together and the flow behavior characterized with velocity flow profiles, mean boundary layer parameters, and turbulence quantities. Laminarization was identified and the influence of acceleration and curvature was characterized.
Characterizing repulsive gravity with curvature eigenvalues
NASA Astrophysics Data System (ADS)
Luongo, Orlando; Quevedo, Hernando
2014-10-01
Repulsive gravity has been investigated in several scenarios near compact objects by using different intuitive approaches. Here, we propose an invariant method to characterize regions of repulsive gravity, associated to black holes and naked singularities. Our method is based upon the behavior of the curvature tensor eigenvalues, and leads to an invariant definition of a repulsion radius. The repulsion radius determines a physical region, which can be interpreted as a repulsion sphere, where the effects due to repulsive gravity naturally arise. Further, we show that the use of effective masses to characterize repulsion regions can lead to coordinate-dependent results whereas, in our approach, repulsion emerges as a consequence of the spacetime geometry in a completely invariant way. Our definition is tested in the spacetime of an electrically charged Kerr naked singularity and in all its limiting cases. We show that a positive mass can generate repulsive gravity if it is equipped with an electric charge or an angular momentum. We obtain reasonable results for the spacetime regions contained inside the repulsion sphere whose size and shape depend on the value of the mass, charge and angular momentum. Consequently, we define repulsive gravity as a classical relativistic effect by using the geometry of spacetime only.
Mirror with thermally controlled radius of curvature
Neil, George R.; Shinn, Michelle D.
2010-06-22
A radius of curvature controlled mirror for controlling precisely the focal point of a laser beam or other light beam. The radius of curvature controlled mirror provides nearly spherical distortion of the mirror in response to differential expansion between the front and rear surfaces of the mirror. The radius of curvature controlled mirror compensates for changes in other optical components due to heating or other physical changes. The radius of curvature controlled mirror includes an arrangement for adjusting the temperature of the front surface and separately adjusting the temperature of the rear surface to control the radius of curvature. The temperature adjustment arrangements can include cooling channels within the mirror body or convection of a gas upon the surface of the mirror. A control system controls the differential expansion between the front and rear surfaces to achieve the desired radius of curvature.
Measurement of curvature and twist of a deformed object using digital holography
Chen Wen; Quan Chenggen; Cho Jui Tay
2008-05-20
Measurement of curvature and twist is an important aspect in the study of object deformation. In recent years, several methods have been proposed to determine curvature and twist of a deformed object using digital shearography. Here we propose a novel method to determine the curvature and twist of a deformed object using digital holography and a complex phasor. A sine/cosine transformation method and two-dimensional short time Fourier transform are proposed subsequently to process the wrapped phase maps. It is shown that high-quality phase maps corresponding to curvature and twist can be obtained. An experiment is conducted to demonstrate the validity of the proposed method.
[Frequency and most common localisation of root canal curvature].
Blasković-Subat, V
1991-01-01
The root canal therapy of the curved canals is a complex operative procedure. Therefore 260 root canals were analysed radiologically to determine the frequency and the most common localisation of the root canal curvature. The frequency of the curved canals averaged at 59%, being greater in the sample of posterior than in the anterior teeth (p less than 0.05). The root canal curvature was most frequently localised at the apical third part (53.9%), followed by the cervical (33.3%) and the middle (12.8%) third part. The apical curvature was predominant in the sample of the anterior, while the cervical predominant (45.2%) in the sample of the posterior teeth. This study pointed out that the frequency of the curved canals is rather high. Consequently, the necessity for practising the modern root canal preparation techniques, bearing in mind their potential danger, is emphasized. PMID:1819932
DNA origami with complex curvatures in three-dimensional space.
Han, Dongran; Pal, Suchetan; Nangreave, Jeanette; Deng, Zhengtao; Liu, Yan; Yan, Hao
2011-04-15
We present a strategy to design and construct self-assembling DNA nanostructures that define intricate curved surfaces in three-dimensional (3D) space using the DNA origami folding technique. Double-helical DNA is bent to follow the rounded contours of the target object, and potential strand crossovers are subsequently identified. Concentric rings of DNA are used to generate in-plane curvature, constrained to 2D by rationally designed geometries and crossover networks. Out-of-plane curvature is introduced by adjusting the particular position and pattern of crossovers between adjacent DNA double helices, whose conformation often deviates from the natural, B-form twist density. A series of DNA nanostructures with high curvature--such as 2D arrangements of concentric rings and 3D spherical shells, ellipsoidal shells, and a nanoflask--were assembled. PMID:21493857
Waterfall field in hybrid inflation and curvature perturbation
Gong, Jinn-Ouk; Sasaki, Misao E-mail: misao@yukawa.kyoto-u.ac.jp
2011-03-01
We study carefully the contribution of the waterfall field to the curvature perturbation at the end of hybrid inflation. In particular we clarify the parameter dependence analytically under reasonable assumptions on the model parameters. After calculating the mode function of the waterfall field, we use the δN formalism and confirm the previously obtained result that the power spectrum is very blue with the index 4 and is absolutely negligible on large scales. However, we also find that the resulting curvature perturbation is highly non-Gaussian and hence we calculate the bispectrum. We find that the bispectrum is at leading order independent of momentum and exhibits its peak at the equilateral limit, though it is unobservably small on large scales. We also present the one-point probability distribution function of the curvature perturbation.
Radius of curvature controlled mirror
Neil, George R.; Rathke, John Wickham; Schultheiss, Thomas John; Shinn, Michelle D.; Dillon-Townes, Lawrence A.
2006-01-17
A controlled radius of curvature mirror assembly comprising: a distortable mirror having a reflective surface and a rear surface; and in descending order from the rear surface; a counter-distortion plate; a flow diverter having a flow diverter aperture at the center thereof; a flow return plate having a flow return aperture at the center thereof; a thermal isolation plate having a thermal isolation plate aperture at the center thereof and a flexible heater having a rear surface and a flexible heater aperture at the center thereof; a double walled tube defining a coolant feed chamber and a coolant return chamber; said coolant feed chamber extending to and through the flow diverter aperture and terminating at the counter-distortion plate and the coolant return chamber extending to and through the thermal isolation backplate and terminating at the flow diverter; and a coolant feed and a coolant return exit at the rear of said flexible heater.
Determinants of Curvature-Sensing Behavior for MARCKS-Fragment Peptides.
de Jesus, Armando J; White, Ormacinda R; Flynn, Aaron D; Yin, Hang
2016-05-10
It is increasingly recognized that membrane curvature plays an important role in various cellular activities such as signaling and trafficking, as well as key issues involving health and disease development. Thus, curvature-sensing peptides are essential to the study and detection of highly curved bilayer structures. The effector domain of myristoylated alanine-rich C-kinase substrate (MARCKS-ED) has been demonstrated to have curvature-sensing ability. Research of the MARCKS-ED has further revealed that its Lys and Phe residues play an essential role in how MARCKS-ED detects and binds to curved bilayers. MARCKS-ED has the added property of being a lower-molecular-weight curvature sensor, which offers advantages in production. With that in mind, this work investigates peptide-sequence-related factors that influence curvature sensing and explores whether peptide fragments of even shorter length can function as curvature sensors. Using both experimental and computational methods, we studied the curvature-sensing capabilities of seven fragments of MARCKS-ED. Two of the longer fragments were designed from approximately the two halves of the full-length peptide whereas the five shorter fragments were taken from the central stretch of MARCKS-ED. Fully atomistic molecular dynamics simulations show that the fragments that remain bound to the bilayer exhibit interactions with the bilayer similar to that of the full-length MARCKS-ED peptide. Fluorescence enhancement and anisotropy assays, meanwhile, reveal that five of the MARCKS fragments possess the ability to sense membrane curvature. Based on the sequences of the curvature-sensing fragments, it appears that the ability to sense curvature involves a balance between the numbers of positively charged residues and hydrophobic anchoring residues. Together, these findings help crystallize our understanding of the molecular mechanisms underpinning the curvature-sensing behaviors of peptides, which will prove useful in the
Kestoras, M.D.; Simon, T.W.
1995-04-01
Experiments are conducted on a flat recovery wall downstream of sustained concave curvature in the presence of high free-stream turbulence (TI {approximately} 8%). This flow simulates some of the features of the flow on the latter parts of the pressure surface of a gas turbine airfoil. The combined effects of concave curvature and TI, both present in the flow over a turbine airfoil, have so far been little studied. Computation of such flows with standard turbulence closure models has not been particularly successful. This experiment attempts to characterize the turbulence characteristics of this flow. In the present study, a turbulent boundary layer grows from the leading edge of a concave wall, then passes onto a downstream flat wall. Results show that turbulence intensities increase profoundly in the outer region of the boundary layer over the recovery wall. Near-wall turbulent eddies appear to lift off the recovery wall and a stabilized region forms near the wall. In contrast to a low-free-stream turbulence intensity flow, turbulent eddies penetrate the outer parts of the stabilized region where sharp velocity and temperature gradients exist. These eddies can more readily transfer momentum and heat. As a result, skin friction coefficients and Stanton numbers on the recovery wall are 20 and 10%, respectively, above their values in the low-free-stream turbulence intensity case. Stanton numbers do not undershoot flat-wall expectations at the same Re{sub {Delta}2} values as seen in the low-TI case. Remarkably, the velocity distribution in the core of the flow over the recovery wall exhibits a negative gradient normal to the wall under high-free-stream turbulence intensity conditions. This velocity distribution appears to be the result of two effects: (1) cross transport of kinetic energy by boundary work in the upstream curved flow and (2) readjustment of static pressure profiles in response to the removal of concave curvature.
Negative curvature fibres: exploiting the potential for novel optical sensors
NASA Astrophysics Data System (ADS)
Novo, C. C.; Urich, A.; Choudhury, D.; Carter, R.; Hand, D. P.; Thomson, R. R.; Yu, F.; Knight, J. C.; Brooks, S.; Mcculloch, S.; Shephard, J. D.
2015-09-01
One of the main challenges for fibre optic based sensing is robust operation in the mid-infrared (mid-IR) region. This is of major interest because this wavelength region is where the characteristic absorption spectra for a wide range of molecules lie. However, due to the high absorption of silica (above 2 μm), mid-IR sensors based on solid core silica fibres are not practical. Of the many alternatives to solid silica fibres, hollow core microstrutured optical fibres are being explored and show great promise. One relatively new fibre, the hollow core negative curvature fibre (NCF) is promising for novel optical devices due to the simple structure (in comparison to other microstructured fibres) in combination with a hollow core which enables low loss mid-IR infrared guidance in a silica based fibre. In this paper, an all silica NCF that is post-processed with a fs laser, in order to increase access to the hollow core, is presented with acceptable loss and significant potential for mid-IR gas sensing.
Determining wave direction using curvature parameters.
de Queiroz, Eduardo Vitarelli; de Carvalho, João Luiz Baptista
2016-01-01
The curvature of the sea wave was tested as a parameter for estimating wave direction in the search for better results in estimates of wave direction in shallow waters, where waves of different sizes, frequencies and directions intersect and it is difficult to characterize. We used numerical simulations of the sea surface to determine wave direction calculated from the curvature of the waves. Using 1000 numerical simulations, the statistical variability of the wave direction was determined. The results showed good performance by the curvature parameter for estimating wave direction. Accuracy in the estimates was improved by including wave slope parameters in addition to curvature. The results indicate that the curvature is a promising technique to estimate wave directions.•In this study, the accuracy and precision of curvature parameters to measure wave direction are analyzed using a model simulation that generates 1000 wave records with directional resolution.•The model allows the simultaneous simulation of time-series wave properties such as sea surface elevation, slope and curvature and they were used to analyze the variability of estimated directions.•The simultaneous acquisition of slope and curvature parameters can contribute to estimates wave direction, thus increasing accuracy and precision of results. PMID:27408830
Three-dimensional ultrasound palmprint recognition using curvature methods
NASA Astrophysics Data System (ADS)
Iula, Antonio; Nardiello, Donatella
2016-05-01
Palmprint recognition systems that use three-dimensional (3-D) information of the palm surface are the most recently explored techniques to overcome some two-dimensional palmprint difficulties. These techniques are based on light structural imaging. In this work, a 3-D ultrasound palmprint recognition system is proposed and evaluated. Volumetric images of a region of the human hand are obtained by moving an ultrasound linear array along its elevation direction and one by one acquiring a number of B-mode images, which are then grouped in a 3-D matrix. The acquisition time was contained in about 5 s. Much information that can be exploited for 3-D palmprint recognition is extracted from the ultrasound volumetric images, including palm curvature and other under-skin information as the depth of the various traits. The recognition procedure developed in this work is based on the analysis of the principal curvatures of palm surface, i.e., mean curvature image, Gaussian curvature image, and surface type. The proposed method is evaluated by performing verification and identification experiments. Preliminary results have shown that the proposed system exhibits an acceptable recognition rate. Further possible improvements of the proposed technique are finally highlighted and discussed.
Protein-Induced Membrane Curvature Alters Local Membrane Tension
Rangamani, Padmini; Mandadap, Kranthi K.; Oster, George
2014-01-01
Adsorption of proteins onto membranes can alter the local membrane curvature. This phenomenon has been observed in biological processes such as endocytosis, tubulation, and vesiculation. However, it is not clear how the local surface properties of the membrane, such as membrane tension, change in response to protein adsorption. In this article, we show that the partial differential equations arising from classical elastic model of lipid membranes, which account for simultaneous changes in shape and membrane tension due to protein adsorption in a local region, cannot be solved for nonaxisymmetric geometries using straightforward numerical techniques; instead, a viscous-elastic formulation is necessary to fully describe the system. Therefore, we develop a viscous-elastic model for inhomogeneous membranes of the Helfrich type. Using the newly available viscous-elastic model, we find that the lipids flow to accommodate changes in membrane curvature during protein adsorption. We show that, at the end of protein adsorption process, the system sustains a residual local tension to balance the difference between the actual mean curvature and the imposed spontaneous curvature. We also show that this change in membrane tension can have a functional impact such as altered response to pulling forces in the presence of proteins. PMID:25099814
NASA Astrophysics Data System (ADS)
Hayashi, Tatsuro; Zhou, Xiangrong; Chen, Huayue; Hara, Takeshi; Miyamoto, Kei; Kobayashi, Tatsunori; Yokoyama, Ryujiro; Kanematsu, Masayuki; Hoshi, Hiroaki; Fujita, Hiroshi
2010-03-01
X-ray CT images have been widely used in clinical routine in recent years. CT images scanned by a modern CT scanner can show the details of various organs and tissues. This means various organs and tissues can be simultaneously interpreted on CT images. However, CT image interpretation requires a lot of time and energy. Therefore, support for interpreting CT images based on image-processing techniques is expected. The interpretation of the spinal curvature is important for clinicians because spinal curvature is associated with various spinal disorders. We propose a quantification scheme of the spinal curvature based on the center line of spinal canal on CT images. The proposed scheme consists of four steps: (1) Automated extraction of the skeletal region based on CT number thresholding. (2) Automated extraction of the center line of spinal canal. (3) Generation of the median plane image of spine, which is reformatted based on the spinal canal. (4) Quantification of the spinal curvature. The proposed scheme was applied to 10 cases, and compared with the Cobb angle that is commonly used by clinicians. We found that a high-correlation (for the 95% confidence interval, lumbar lordosis: 0.81-0.99) between values obtained by the proposed (vector) method and Cobb angle. Also, the proposed method can provide the reproducible result (inter- and intra-observer variability: within 2°). These experimental results suggested a possibility that the proposed method was efficient for quantifying the spinal curvature on CT images.
High School Attrition Rates Across Texas Education Service Center Regions
ERIC Educational Resources Information Center
Johnson, Roy
2008-01-01
The examination of historical trend data on the number and percent of students lost from public school enrollment prior to graduation from high school is becoming increasingly important since distinct trends are emerging on a regional basis. This study examines regional trends in Texas on the number and percent of students lost from public high…
Programming curvature using origami tessellations
NASA Astrophysics Data System (ADS)
Dudte, Levi H.; Vouga, Etienne; Tachi, Tomohiro; Mahadevan, L.
2016-05-01
Origami describes rules for creating folded structures from patterns on a flat sheet, but does not prescribe how patterns can be designed to fit target shapes. Here, starting from the simplest periodic origami pattern that yields one-degree-of-freedom collapsible structures--we show that scale-independent elementary geometric constructions and constrained optimization algorithms can be used to determine spatially modulated patterns that yield approximations to given surfaces of constant or varying curvature. Paper models confirm the feasibility of our calculations. We also assess the difficulty of realizing these geometric structures by quantifying the energetic barrier that separates the metastable flat and folded states. Moreover, we characterize the trade-off between the accuracy to which the pattern conforms to the target surface, and the effort associated with creating finer folds. Our approach enables the tailoring of origami patterns to drape complex surfaces independent of absolute scale, as well as the quantification of the energetic and material cost of doing so.
Ionic liquid tunes microemulsion curvature.
Liu, Liping; Bauduin, Pierre; Zemb, Thomas; Eastoe, Julian; Hao, Jingcheng
2009-02-17
Middle-phase microemulsions formed from cationic dioctadecyldimethylammonium chloride (DODMAC), anionic sodium dodecylsulfate (SDS), n-butanol, and n-heptane were studied. An ionic liquid (IL), 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim][BF4]), was employed as the electrolyte in the aqueous media instead of inorganic salts usually used in microemulsion formulation. Studies have been carried out as a function of the concentrations of [bmim][BF4], n-butanol, total surfactant (cDODMAC+SDS), and temperature on the phase behavior and the ultralow interfacial tensions in which the anionic component is present in excess in the catanionic film. Ultralow interfacial tension measurements confirmed the formation of middle-phase microemulsions and the necessary conditions for stabilizing middle-phase microemulsions. Electrical conductivity, small-angle X-ray scattering (SAXS), and small-angle neutron scattering (SANS) experiments were also performed, indicating that the typical heptane domain size has an average radius of 360 A and the ionic liquid induces softening of the charged catanionic film. Most interestingly, the IL concentration (cIL) is shown to act as an effective interfacial curvature-control parameter, representing a new approach to tuning the formulation of microemulsions and emulsions. The results expand the potential uses of ILs but also point to the design of new ILs that may achieve superefficient control over interfacial and self-assembly systems. PMID:19161325
Negative voltage bandgap reference with multilevel curvature compensation technique
NASA Astrophysics Data System (ADS)
Xi, Liu; Qian, Liu; Xiaoshi, Jin; Yongrui, Zhao; Lee, Jong-Ho
2016-05-01
A novel high-order curvature compensation negative voltage bandgap reference (NBGR) based on a novel multilevel compensation technique is introduced. Employing an exponential curvature compensation (ECC) term with many high order terms in itself, in a lower temperature range (TR) and a multilevel curvature compensation (MLCC) term in a higher TR, a flattened and better effect of curvature compensation over the TR of 165 °C (‑40 to 125 °C) is realised. The MLCC circuit adds two convex curves by using two sub-threshold operated NMOS. The proposed NBGR implemented in the Central Semiconductor Manufacturing Corporation (CSMC) 0.5 μm BCD technology demonstrates an accurate voltage of ‑1.183 V with a temperature coefficient (TC) as low as 2.45 ppm/°C over the TR of 165 °C at a ‑5.0 V power supply; the line regulation is 3 mV/V from a ‑5 to ‑2 V supply voltage. The active area of the presented NBGR is 370 × 180 μm2. Project supported by the Fund of Liaoning Province Education Department (No. L2013045).
The high-force region of the force-velocity relation in frog skinned muscle fibres.
Lou, F; Sun, Y B
1993-07-01
The force-velocity relation has been studied during calcium-induced contracture of chemically skinned fibres from the semitendinosus muscle of Rana temporaria with special interest focused on the high-load region. The force-velocity curve was hyperbolic at low and intermediate loads but departed below the hyperbola as the load exceeded about 80% of the isometric force (P0). The force intercept (P*0) of the hyperbola derived from force-velocity data truncated at 0.78 P0 was higher than P0 (P*0/P0 = 1.14 +/- 0.04). At submaximum Ca2+ concentration, where the isometric force of the fibre was 65-75% of the maximum value, the force-velocity data still departed below the hyperbola at high loads (P*0/P0 = 1.09 +/- 0.04). The departure of the force-velocity data from the hyperbola at high force was also found at high ionic strength (250 mM), but not at low ionic strength (150 mM) (P*0/P0 = 1.09 +/- 0.03 and 0.98 +/- 0.03, respectively). The force-velocity relations derived under different experimental conditions could be fitted well by a modified version of Hill's (1938) hyperbolic equation (Edman 1988) using similar numerical values of k1 and k2 in the latter equation. The results indicate that the force-velocity relation in skinned muscle fibres is biphasic, and that the two curvatures, as in intact muscle fibres, are closely related to one another. Furthermore the evidence supports the hypothesis that the altered shape of the force-velocity relation at high loads is not related to the force level per se but rather to the speed of shortening of the contractile system (Edman 1992). PMID:8213180
Soliton curvatures of surfaces and spaces
Konopelchenko, B.G.
1997-01-01
An intrinsic geometry of surfaces and three-dimensional Riemann spaces is discussed. In the geodesic coordinates the Gauss equation for two-dimensional Riemann spaces (surfaces) is reduced to the one-dimensional Schr{umlt o}dinger equation, where the Gaussian curvature plays a role of potential. The use of this fact provides an infinite set of explicit expressions for curvature and metric of surface. A special case is governed by the KdV equation for the Gaussian curvature. Integrable dynamics of curvature via the KdV equation, higher KdV equations, and 2+1-dimensional integrable equations with breaking solitons is considered. For a special class of three-dimensional Riemann spaces the relation between metric and scalar curvature is given by the two-dimensional stationary Schr{umlt o}dinger or perturbed string equations. This provides us an infinite family of Riemann spaces with explicit scalar curvature and metric. Particular class of spaces and their integrable evolutions are described by the Nizhnik{endash}Veselov{endash}Novikov equation and its higher analogs. Surfaces and three-dimensional Riemann spaces with large curvature and slow dependence on the variable are considered. They are associated with the Burgers and Kadomtsev{endash}Petviashvili equations, respectively. {copyright} {ital 1997 American Institute of Physics.}
Variation and Heritability in Hair Diameter and Curvature in an Australian Twin Sample.
Ho, Yvonne Y W; Brims, Mark; McNevin, Dennis; Spector, Timothy D; Martin, Nicholas G; Medland, Sarah E
2016-08-01
Hair diameter and curvature are two characteristics of human scalp hair used in forensic contexts. While previous data show that subjective categorization of hair curvature is highly heritable, the heritability of objectively measured curvature and diameter, and variability of hair characteristics within each individual have not yet been studied. The present study measured hair diameter and curvature using an optical fiber diameter analyzer in a sample of 2,332 twins and siblings. Heritability was estimated using maximum likelihood structural equation modeling. Results show sex differences in the magnitude of genetic influence for mean diameter and curvature, with the vast majority of the variance accounted for by genetic effects in males (diameter = 86%, curvature = 53%) and females (diameter = 77%, curvature = 61%). The consistency of diameter (variance within an individual) was also highly heritable, but did not show sex limitation, with 68% of the variance accounted for by genetic factors. Moderate phenotypic correlations were seen between diameter and consistency (r = 0.3) but there was little correlation between diameter and curvature (r = -0.13). A bivariate Cholesky analysis was used to estimate the genetic and environmental correlations between hair diameter and consistency, yielding genetic correlations of r gF = 0.27 for females and r gM = 0.25 for males. PMID:27291867
Distributed curvature and stability of fullerenes.
Fowler, Patrick W; Nikolić, Sonja; De Los Reyes, Rasthy; Myrvold, Wendy
2015-09-21
Energies of non-planar conjugated π systems are typically described qualitatively in terms of the balance of π stabilisation and the steric strain associated with geometric curvature. Curvature also has a purely graph-theoretical description: combinatorial curvature at a vertex of a polyhedral graph is defined as one minus half the vertex degree plus the sum of reciprocal sizes of the faces meeting at that vertex. Prisms and antiprisms have positive combinatorial vertex curvature at every vertex. Excluding these two infinite families, we call any other polyhedron with everywhere positive combinatorial curvature a PCC polyhedron. Cubic PCC polyhedra are initially common, but must eventually die out with increasing vertex count; the largest example constructed so far has 132 vertices. The fullerenes Cn have cubic polyhedral molecular graphs with n vertices, 12 pentagonal and (n/2 - 10) hexagonal faces. We show that there are exactly 39 PCC fullerenes, all in the range 20 ≤n≤ 60. In this range, there is only partial correlation between PCC status and stability as defined by minimum pentagon adjacency. The sum of vertex curvatures is 2 for any polyhedron; for fullerenes the sum of squared vertex curvatures is linearly related to the number of pentagon adjacencies and hence is a direct measure of relative stability of the lower (n≤ 60) fullerenes. For n≥ 62, non-PCC fullerenes with a minimum number of pentagon adjacencies minimise mean-square curvature. For n≥ 70, minimum mean-square curvature implies isolation of pentagons, which is the strongest indicator of stability for a bare fullerene. PMID:26283188
Kegulian, Natalie C; Sankhagowit, Shalene; Apostolidou, Melania; Jayasinghe, Sajith A; Malmstadt, Noah; Butler, Peter C; Langen, Ralf
2015-10-23
Islet amyloid polypeptide (IAPP) is a 37-amino acid amyloid protein intimately associated with pancreatic islet β-cell dysfunction and death in type II diabetes. In this study, we combine spectroscopic methods and microscopy to investigate α-helical IAPP-membrane interactions. Using light scattering and fluorescence microscopy, we observe that larger vesicles become smaller upon treatment with human or rat IAPP. Electron microscopy shows the formation of various highly curved structures such as tubules or smaller vesicles in a membrane-remodeling process, and spectrofluorometric detection of vesicle leakage shows disruption of membrane integrity. This effect is stronger for human IAPP than for the less toxic rat IAPP. From CD spectra in the presence of different-sized vesicles, we also uncover the membrane curvature-sensing ability of IAPP and find that it transitions from inducing to sensing membrane curvature when lipid negative charge is decreased. Our in vivo EM images of immunogold-labeled rat IAPP and human IAPP show both forms to localize to mitochondrial cristae, which contain not only locally curved membranes but also phosphatidylethanolamine and cardiolipin, lipids with high spontaneous negative curvature. Disruption of membrane integrity by induction of membrane curvature could apply more broadly to other amyloid proteins and be responsible for membrane damage observed in other amyloid diseases as well. PMID:26283787
NASA Astrophysics Data System (ADS)
Kestoras, M. D.; Simon, T. W.
1995-04-01
In an attempt to characterize the turbulence characteristics of the high free-stream turbulence (TI approximately 8%) flow, several experiments are conducted on a flat recovery wall downstream of sustained concave curvature in the presence of such flow. A turbulent boundary layer that grows from the leading edge of a concave wall, then passes onto a downstream flat wall is considered. The results indicate that turbulence intensities increase profoundly in the outer region of the boundary layer over the recovery wall. The recovery wall is found to be lifted off by near-wall turbulent eddies while a 'stabilized' region forms near the wall. Contrary to the low-free-stream turbulence intensity flow, turbulent eddies penetrate the outer parts of the 'stabilized' region. The behavior of the Stanton numbers as well as the velocity distribution on the core of the flow are also accounted for.
Magnetic curvature effects on plasma interchange turbulence
NASA Astrophysics Data System (ADS)
Li, B.; Liao, X.; Sun, C. K.; Ou, W.; Liu, D.; Gui, G.; Wang, X. G.
2016-06-01
The magnetic curvature effects on plasma interchange turbulence and transport in the Z-pinch and dipole-like systems are explored with two-fluid global simulations. By comparing the transport levels in the systems with a different magnetic curvature, we show that the interchange-mode driven transport strongly depends on the magnetic geometry. For the system with large magnetic curvature, the pressure and density profiles are strongly peaked in a marginally stable state and the nonlinear evolution of interchange modes produces the global convective cells in the azimuthal direction, which lead to the low level of turbulent convective transport.
Effect of track asymmetry and curvature on shingle writing scheme
NASA Astrophysics Data System (ADS)
Liu, Feng; Li, Shaoping; Bai, Daniel; Mendez, Hector; Pan, Tao; Han, Dehua; Mao, Sining
2011-04-01
Written transition curvature in perpendicular magnetic recording is generally understood to result in increased transition jitter noise and degraded signal to noise ratio or byte error rate (BER) performance. For the shingle writing scheme, asymmetry or curvature in written tracks is considered inherent due to the erasure and track edge writing characteristics. It is proposed that such a track asymmetry is more prominent at high track density/smaller track pitch recording conditions. In this report we present spin stand experimental results to study the effect of the possible track asymmetry or curvature by shingle writing and reading back in different skews. By comparing shingle writing BER bathtub profiles in different writing skew conditions 0°, +/-2°, +/-4°, +/-6°, the effect of varying shingle track asymmetry and curvature is analyzed via subsequent skewed reading process. The shingle writing BER bathtub profiles as well as the read back amplitude cross track profile are generally symmetric upon one sided erasure at different track pitches. We found that the 0° skew writing and reading process provides both the maximum BER and amplitude.
Intracellular magnetophoresis of amyloplasts and induction of root curvature
NASA Technical Reports Server (NTRS)
Kuznetsov, O. A.; Hasenstein, K. H.
1996-01-01
High-gradient magnetic fields (HGMFs) were used to induce intracellular magnetophoresis of amyloplasts. The HGMFs were generated by placing a small ferromagnetic wedge into a uniform magnetic field or at the gap edge between two permanent magnets. In the vicinity of the tip of the wedge the dynamic factor of the magnetic field, delta(H2/2), was about 10(9) Oe2.cm-1, which subjected the amyloplasts to a force comparable to that of gravity. When roots of 2-d-old seedlings of flax (Linum usitatissimum L.) were positioned vertically and exposed to an HGMF, curvature away from the wedge was transient and lasted approximately 1 h. Average curvature obtained after placing magnets, wedge and seedlings on a 1-rpm clinostat for 2 h was 33 +/- 5 degrees. Roots of horizontally placed control seedlings without rotation curved about 47 +/- 4 degrees. The time course of curvature and changes in growth rate were similar for gravicurvature and for root curvature induced by HGMFs. Microscopy showed displacement of amyloplasts in vitro and in vivo. Studies with Arabidopsis thaliana (L.) Heynh. showed that the wild type responded to HGMFs but the starchless mutant TC7 did not. The data indicate that a magnetic force can be used to study the gravisensing and response system of roots.
Non-perturbative approach for curvature perturbations in stochastic δ N formalism
Fujita, Tomohiro; Kawasaki, Masahiro; Tada, Yuichiro E-mail: kawasaki@icrr.u-tokyo.ac.jp
2014-10-01
In our previous paper [1], we have proposed a new algorithm to calculate the power spectrum of the curvature perturbations generated in inflationary universe with use of the stochastic approach. Since this algorithm does not need the perturbative expansion with respect to the inflaton fields on super-horizon scale, it works even in highly stochastic cases. For example, when the curvature perturbations are very large or the non-Gaussianities of the curvature perturbations are sizable, the perturbative expansion may break down but our algorithm enables to calculate the curvature perturbations. We apply it to two well-known inflation models, chaotic and hybrid inflation, in this paper. Especially for hybrid inflation, while the potential is very flat around the critical point and the standard perturbative computation is problematic, we successfully calculate the curvature perturbations.
Sha, Haoyan; Faller, Roland
2016-07-20
Quantum chemistry calculations were performed to investigate the effect of the surface curvature of a Boron Nitride (BN) nanotube/nanosheet on gas adsorption. Curved boron nitride layers with different curvatures interacting with a number of different gases including noble gases, oxygen, and water on both their convex and concave sides of the surface were studied using density functional theory (DFT) with a high level dispersion corrected functional. Potential energy surfaces of the gas molecules interacting with the selected BN surfaces were investigated. In addition, the charge distribution and electrostatic potential contour of the selected BN surfaces are discussed. The results reveal how the curvature of the BN surfaces affects gas adsorption. In particular, small curvatures lead to a slight difference in the physisorption energy, while large curvatures present distinct potential energy surfaces, especially for the short-range repulsion. PMID:27399852
Turbine component casting core with high resolution region
Kamel, Ahmed; Merrill, Gary B.
2014-08-26
A hollow turbine engine component with complex internal features can include a first region and a second, high resolution region. The first region can be defined by a first ceramic core piece formed by any conventional process, such as by injection molding or transfer molding. The second region can be defined by a second ceramic core piece formed separately by a method effective to produce high resolution features, such as tomo lithographic molding. The first core piece and the second core piece can be joined by interlocking engagement that once subjected to an intermediate thermal heat treatment process thermally deform to form a three dimensional interlocking joint between the first and second core pieces by allowing thermal creep to irreversibly interlock the first and second core pieces together such that the joint becomes physically locked together providing joint stability through thermal processing.
Anisotropic Membrane Curvature Sensing by Amphipathic Peptides.
Gómez-Llobregat, Jordi; Elías-Wolff, Federico; Lindén, Martin
2016-01-01
Many proteins and peptides have an intrinsic capacity to sense and induce membrane curvature, and play crucial roles for organizing and remodeling cell membranes. However, the molecular driving forces behind these processes are not well understood. Here, we describe an approach to study curvature sensing by simulating the interactions of single molecules with a buckled lipid bilayer. We analyze three amphipathic antimicrobial peptides, a class of membrane-associated molecules that specifically target and destabilize bacterial membranes, and find qualitatively different sensing characteristics that would be difficult to resolve with other methods. Our findings provide evidence for direction-dependent curvature sensing mechanisms in amphipathic peptides and challenge existing theories of hydrophobic insertion. The buckling approach is generally applicable to a wide range of curvature-sensing molecules, and our results provide strong motivation to develop new experimental methods to track position and orientation of membrane proteins. PMID:26745422
Gravitropic basis of leaf blade nastic curvatures
NASA Technical Reports Server (NTRS)
Hayes, A. B.
1982-01-01
The curvatures produced in leaf blades by auxin treatment have been described as nastic curvatures because the initial differential growth is always enhanced on the lower side, regardless of the side of application. It is now known, however, that blades can show differential growth of either the upper or the lower side depending on the conditions of treatment. The dorsiventrality of the blade therefore influences but does not limit the direction of curvature. The dorsiventral directionality of response to growth regulators and the response to changes in the orientation to gravity are seen as indicating that blade curvatures are analogous to negative or positive gravitropism. It is noted that neither blade hyponasty or epinasty can be accounted for by ethylene alone. Petiole responses, however, are not directional, and the leaf angle changes induced by rotation or auxin treatment can be accounted for by ethylene production.
Spline-Based Smoothing of Airfoil Curvatures
NASA Technical Reports Server (NTRS)
Li, W.; Krist, S.
2008-01-01
Constrained fitting for airfoil curvature smoothing (CFACS) is a splinebased method of interpolating airfoil surface coordinates (and, concomitantly, airfoil thicknesses) between specified discrete design points so as to obtain smoothing of surface-curvature profiles in addition to basic smoothing of surfaces. CFACS was developed in recognition of the fact that the performance of a transonic airfoil is directly related to both the curvature profile and the smoothness of the airfoil surface. Older methods of interpolation of airfoil surfaces involve various compromises between smoothing of surfaces and exact fitting of surfaces to specified discrete design points. While some of the older methods take curvature profiles into account, they nevertheless sometimes yield unfavorable results, including curvature oscillations near end points and substantial deviations from desired leading-edge shapes. In CFACS as in most of the older methods, one seeks a compromise between smoothing and exact fitting. Unlike in the older methods, the airfoil surface is modified as little as possible from its original specified form and, instead, is smoothed in such a way that the curvature profile becomes a smooth fit of the curvature profile of the original airfoil specification. CFACS involves a combination of rigorous mathematical modeling and knowledge-based heuristics. Rigorous mathematical formulation provides assurance of removal of undesirable curvature oscillations with minimum modification of the airfoil geometry. Knowledge-based heuristics bridge the gap between theory and designers best practices. In CFACS, one of the measures of the deviation of an airfoil surface from smoothness is the sum of squares of the jumps in the third derivatives of a cubicspline interpolation of the airfoil data. This measure is incorporated into a formulation for minimizing an overall deviation- from-smoothness measure of the airfoil data within a specified fitting error tolerance. CFACS has been
Induced gravity from curvature density preserving diffeomorphisms
NASA Astrophysics Data System (ADS)
Oda, Ichiro
2016-08-01
We construct not only an induced gravity model with restricted diffeomorphisms, that is, transverse diffeomorphisms that preserve the curvature density, but also with full diffeomorphisms. By solving the equations of motion, it turns out that these models produce Einstein's equations with a certain Newton constant in addition to the constraint for the curvature density. In the limit of the infinite Newton constant, the models give rise to induced gravity. Moreover, we discuss cosmological solutions on the basis of the gravitational models at hand.
Curvature tensors unified field equations on SEXn
NASA Astrophysics Data System (ADS)
Chung, Kyung Tae; Lee, Il Young
1988-09-01
We study the curvature tensors and field equations in the n-dimensional SE manifold SEXn. We obtain several basic properties of the vectors S λ and U λ and then of the SE curvature tensor and its contractions, such as a generalized Ricci identity, a generalized Bianchi identity, and two variations of the Bianchi identity satisfied by the SE Einstein tensor. Finally, a system of field equations is discussed in SEXn and one of its particular solutions is constructed and displayed.
The role of curvature in entanglement
NASA Astrophysics Data System (ADS)
Buck, Gregory
2015-10-01
Which tangles more readily: curly hair or straight hair? A perhaps natural thought, supported by some theoretical evidence, is to associate curvature and entanglement, and assume that they would grow together-that an increase in one fosters an increase in the other. However we have biological examples such as DNA in the chromosome, and mechanical examples such as coiled telephone cords, in which much more curvature is employed than is required for the packing, and in which tangling is presumably detrimental. We offer a resolution to this conundrum. We show, that at least for simple but generally applicable models, the relationship between curvature and entanglement is subtle: if we keep filament density constant and increase curvature, the entanglement initially increases, passes through a maximum, then decreases, so there is a regime where increasing curvature increases entanglement, and there is also a regime where increasing curvature decreases entanglement. This has implications for filament packing in many circumstances, and in particular for the compaction structure of DNA in the cell-it provides a straightforward argument for the view that one purpose of DNA coiling and supercoiling is to inhibit entanglement. It also tells us to expect that wavy hair-neither the straightest nor the curliest-tangles most readily.
Spherical gravitational curvature boundary-value problem
NASA Astrophysics Data System (ADS)
Šprlák, Michal; Novák, Pavel
2016-08-01
Values of scalar, vector and second-order tensor parameters of the Earth's gravitational field have been collected by various sensors in geodesy and geophysics. Such observables have been widely exploited in different parametrization methods for the gravitational field modelling. Moreover, theoretical aspects of these quantities have extensively been studied and well understood. On the other hand, new sensors for observing gravitational curvatures, i.e., components of the third-order gravitational tensor, are currently under development. As the gravitational curvatures represent new types of observables, their exploitation for modelling of the Earth's gravitational field is a subject of this study. Firstly, the gravitational curvature tensor is decomposed into six parts which are expanded in terms of third-order tensor spherical harmonics. Secondly, gravitational curvature boundary-value problems defined for four combinations of the gravitational curvatures are formulated and solved in spectral and spatial domains. Thirdly, properties of the corresponding sub-integral kernels are investigated. The presented mathematical formulations reveal some important properties of the gravitational curvatures and extend the so-called Meissl scheme, i.e., an important theoretical framework that relates various parameters of the Earth's gravitational field.
Cosmological attractor models and higher curvature supergravity
NASA Astrophysics Data System (ADS)
Cecotti, Sergio; Kallosh, Renata
2014-05-01
We study cosmological α-attractors in superconformal/supergravity models, where α is related to the geometry of the moduli space. For α = 1 attractors [1] we present a generalization of the previously known manifestly superconformal higher curvature supergravity model [2]. The relevant standard 2-derivative supergravity with a minimum of two chiral multiplets is shown to be dual to a 4-derivative higher curvature supergravity, where in general one of the chiral superfields is traded for a curvature superfield. There is a degenerate case when both matter superfields become non-dynamical and there is only a chiral curvature superfield, pure higher derivative supergravity. Generic α-models [3] interpolate between the attractor point at α = 0 and generic chaotic inflation models at large α, in the limit when the inflaton moduli space becomes flat. They have higher derivative duals with the same number of matter fields as the original theory or less, but at least one matter multiplet remains. In the context of these models, the detection of primordial gravity waves will provide information on the curvature of the inflaton submanifold of the Kähler manifold, and we will learn if the inflaton is a fundamental matter multiplet, or can be replaced by a higher derivative curvature excitation.
Spherical gravitational curvature boundary-value problem
NASA Astrophysics Data System (ADS)
Šprlák, Michal; Novák, Pavel
2016-05-01
Values of scalar, vector and second-order tensor parameters of the Earth's gravitational field have been collected by various sensors in geodesy and geophysics. Such observables have been widely exploited in different parametrization methods for the gravitational field modelling. Moreover, theoretical aspects of these quantities have extensively been studied and well understood. On the other hand, new sensors for observing gravitational curvatures, i.e., components of the third-order gravitational tensor, are currently under development. As the gravitational curvatures represent new types of observables, their exploitation for modelling of the Earth's gravitational field is a subject of this study. Firstly, the gravitational curvature tensor is decomposed into six parts which are expanded in terms of third-order tensor spherical harmonics. Secondly, gravitational curvature boundary-value problems defined for four combinations of the gravitational curvatures are formulated and solved in spectral and spatial domains. Thirdly, properties of the corresponding sub-integral kernels are investigated. The presented mathematical formulations reveal some important properties of the gravitational curvatures and extend the so-called Meissl scheme, i.e., an important theoretical framework that relates various parameters of the Earth's gravitational field.
Wang, Tuo; Hong, Mei
2015-01-01
A wide variety of membrane proteins induce membrane curvature for function, thus it is important to develop new methods to simultaneously determine membrane curvature and protein binding sites in membranes with multiple curvatures. We introduce solid-state NMR methods based on magnetically oriented bicelles and off-magic-angle spinning (OMAS) to measure membrane curvature and the binding site of proteins in mixed-curvature membranes. We demonstrate these methods on the influenza virus M2 protein, which not only acts as a proton channel but also mediates virus assembly and membrane scission. An M2 peptide encompassing the transmembrane (TM) domain and an amphipathic helix, M2(21-61), was studied and compared with the TM peptide (M2TM). Static 31P NMR spectra of magnetically oriented DMPC/DHPC bicelles exhibit a temperature-independent isotropic chemical shift in the presence of M2(21-61) but not M2TM, indicating that the amphipathic helix confers the peptide with the ability to generate a high-curvature phase. 2D 31P spectra indicate that this high-curvature phase is associated with the DHPC bicelle edges, suggestive of the structure of budding viruses from the host cell. 31P- and 13C-detected 1H relaxation times of the lipids indicate that the majority of M2(21-61) is bound to the high-curvature phase. Using OMAS experiments, we resolved the 31P signals of lipids with identical headgroups based on their distinct chemical shift anisotropies. Based on this resolution, 2D 1H-31P correlation spectra show that the amide protons in M2(21-61) correlate with the DMPC but not the DHPC 31P signal of the bicelle, indicating that a small percentage of M2(21-61) partitions into the planar region of the bicelles. These results show that the M2 amphipathic helix induces high membrane curvature and localizes the protein to this phase, in excellent agreement with the membrane-scission function of the protein. These bicelle-based relaxation and OMAS solid-state NMR techniques are
Gridding heterogeneous bathymetric data sets with stacked continuous curvature splines in tension
NASA Astrophysics Data System (ADS)
Hell, Benjamin; Jakobsson, Martin
2011-12-01
Gridding heterogeneous bathymetric data sets for the compilation of Digital bathymetric models (DBMs), poses specific problems when there are extreme variations in source data density. This requires gridding routines capable of subsampling high-resolution source data while preserving as much as possible of the small details, at the same time as interpolating in areas with sparse data without generating gridding artifacts. A frequently used gridding method generalizes bicubic spline interpolation and is known as continuous curvature splines in tension. This method is further enhanced in this article in order to specifically handle heterogeneous bathymetric source data. Our method constructs the final grid through stacking several surfaces of different resolutions, each generated using the splines in tension algorithm. With this approach, the gridding resolution is locally adjusted to the density of the source data set: Areas with high-resolution data are gridded at higher resolution than areas with sparse source data. In comparison with some of the most widely used gridding methods, our approach yields superior DBMs based on heterogeneous bathymetric data sets with regard to preserving small bathymetric details in the high-resolution source data, while minimizing interpolation artifacts in the sparsely data constrained regions. Common problems such as artifacts from ship tracklines are suppressed. Even if our stacked continuous curvature splines in tension gridding algorithm has been specifically designed to construct DBMs from heterogeneous bathymetric source data, it may be used to compile regular grids from other geoscientific measurements.
Chandra Discoveries in High-mass Star-forming Regions
NASA Astrophysics Data System (ADS)
Townsley, L. K.; Broos, P. S.; Feigelson, E. D.; Garmire, G. P.
2004-08-01
Chandra is providing remarkable new views of high-mass star-forming regions, revealing all stages in the life cycle of high-mass stars and their effects on their surroundings. We present a Chandra/ACIS tour of several high-mass star-forming regions, highlighting physical processes that characterize the life of a cluster of high-mass stars, from deeply-embedded cores too young to have established an HII region to superbubbles so large that they shape our views of galaxies. Along the way we see that X-ray observations reveal hundreds of stellar sources powering great HII region complexes, suffused by both hard and soft diffuse X-ray structures caused by fast O-star winds thermalized in wind-wind collisions or by termination shocks against the surrounding media. Finally, we examine the effects of the deaths of high-mass stars that remained close to their birthplaces, exploding as supernovae within the superbubbles that these clusters created.
Seismicity analysis in Indonesia region from high precision hypocenter location
NASA Astrophysics Data System (ADS)
Nugraha, Andri; Shiddiqi, Hasbi; Widiyantoro, Sri; Ramdhan, Mohamad; Wandono, Wandono
2015-04-01
As a complex tectonic region, Indonesia has a high seismicity rate which is related to subduction and collision as well as strike-slip fault. High-precision earthquake locations with adequate relocation method and proper velocity model are necessary for seismicity analysis. We used nearly 25,000 earthquakes that were relocated using double-difference method. In our relocation process, we employed teleseismic, regional, and local P-wave arrival times. Furthermore, we employed regional-global nested velocity models that take into account the subduction slab in the study region by using a 3D model for area inside and a 1D model for area outside Indonesia. Relocation results show shifted hypocenters that are generally perpendicular to the trench. Beneath western Sunda arc, the Wadati-Benioff Zone (WBZ) extents to a depth of about 300 km and depicts a gently dipping slab. The WBZ beneath eastern Sunda arc extends deeper to about 500 km and depicts a steep slab geometry. In the Sunda-Banda transition zone, we found anomalously low seismicity beneath the oceanic-continental transition region. The WBZ of the severely curved Banda arc extends to a depth of about 600 km and depicts a two-slab model. In the Molucca collision zone, seismicity clearly depicts two opposing slabs of the Molucca sea plate, i.e. to the east and to the west. Around Sulawesi region, most earthquakes are related to the north Sulawesi trench and depict subducted slab beneath the northern part of the island. In Sumatra region, we identified a seismic gap in the WBZ between 70 km and 150 km. Seismicity gaps are also detected beneath particular regions, e.g. Mentawai region, and several parts along the subducted slab. Similar to the Sumatra region, beneath eastern Sunda arc, seismic gap in WBZ is also detected but deeper, i.e. at depths of 150 km to 250 km. Furthermore, we used global centroid moment tensor catalog data available for earthquakes with magnitude 5.0 or greater. In general, focal mechanism
Dense molecular gas tracers in high mass star formation regions
NASA Astrophysics Data System (ADS)
Ma, Hong-Jun; Gao, Yu; Wu, Jing-Wen
2016-02-01
We report the FCRAO observations that mapped HCN (1-0), CS (2-1), HNC (1-0) and HCO+ (1-0) in ten high-mass star forming cores associated with water masers. We present velocity integrated intensity maps of the four lines for these dense cores, compare their line profiles, and derive physical properties of these cores. We find that these four tracers identify areas with similar properties in these massive dense cores, and in most cases, the emissions of HCN and HCO+ are stronger than those of HNC and CS. We also use the line ratios of HCO+/HCN, HNC/HCN and HNC/HCO+ as the diagnostics to explore the environment of these high-mass star forming regions, and find that most of the cores agree with the model that photodominated regions dominate the radiation field, except for W44, for which the radiation field is similar to an X-ray dominated region.
Strong curvature effects in Neumann wave problems
Willatzen, M.; Pors, A.; Gravesen, J.
2012-08-15
Waveguide phenomena play a major role in basic sciences and engineering. The Helmholtz equation is the governing equation for the electric field in electromagnetic wave propagation and the acoustic pressure in the study of pressure dynamics. The Schroedinger equation simplifies to the Helmholtz equation for a quantum-mechanical particle confined by infinite barriers relevant in semiconductor physics. With this in mind and the interest to tailor waveguides towards a desired spectrum and modal pattern structure in classical structures and nanostructures, it becomes increasingly important to understand the influence of curvature effects in waveguides. In this work, we demonstrate analytically strong curvature effects for the eigenvalue spectrum of the Helmholtz equation with Neumann boundary conditions in cases where the waveguide cross section is a circular sector. It is found that the linear-in-curvature contribution originates from parity symmetry breaking of eigenstates in circular-sector tori and hence vanishes in a torus with a complete circular cross section. The same strong curvature effect is not present in waveguides subject to Dirichlet boundary conditions where curvature contributions contribute to second-order in the curvature only. We demonstrate this finding by considering wave propagation in a circular-sector torus corresponding to Neumann and Dirichlet boundary conditions, respectively. Results for relative eigenfrequency shifts and modes are determined and compared with three-dimensional finite element method results. Good agreement is found between the present analytical method using a combination of differential geometry with perturbation theory and finite element results for a large range of curvature ratios.
Hydrophobic surfactant proteins strongly induce negative curvature.
Chavarha, Mariya; Loney, Ryan W; Rananavare, Shankar B; Hall, Stephen B
2015-07-01
The hydrophobic surfactant proteins SP-B and SP-C greatly accelerate the adsorption of vesicles containing the surfactant lipids to form a film that lowers the surface tension of the air/water interface in the lungs. Pulmonary surfactant enters the interface by a process analogous to the fusion of two vesicles. As with fusion, several factors affect adsorption according to how they alter the curvature of lipid leaflets, suggesting that adsorption proceeds via a rate-limiting structure with negative curvature, in which the hydrophilic face of the phospholipid leaflets is concave. In the studies reported here, we tested whether the surfactant proteins might promote adsorption by inducing lipids to adopt a more negative curvature, closer to the configuration of the hypothetical intermediate. Our experiments used x-ray diffraction to determine how the proteins in their physiological ratio affect the radius of cylindrical monolayers in the negatively curved, inverse hexagonal phase. With binary mixtures of dioleoylphosphatidylethanolamine (DOPE) and dioleoylphosphatidylcholine (DOPC), the proteins produced a dose-related effect on curvature that depended on the phospholipid composition. With DOPE alone, the proteins produced no change. With an increasing mol fraction of DOPC, the response to the proteins increased, reaching a maximum 50% reduction in cylindrical radius at 5% (w/w) protein. This change represented a doubling of curvature at the outer cylindrical surface. The change in spontaneous curvature, defined at approximately the level of the glycerol group, would be greater. Analysis of the results in terms of a Langmuir model for binding to a surface suggests that the effect of the lipids is consistent with a change in the maximum binding capacity. Our findings show that surfactant proteins can promote negative curvature, and support the possibility that they facilitate adsorption by that mechanism. PMID:26153706
Strong curvature effects in Neumann wave problems
NASA Astrophysics Data System (ADS)
Willatzen, M.; Pors, A.; Gravesen, J.
2012-08-01
Waveguide phenomena play a major role in basic sciences and engineering. The Helmholtz equation is the governing equation for the electric field in electromagnetic wave propagation and the acoustic pressure in the study of pressure dynamics. The Schrödinger equation simplifies to the Helmholtz equation for a quantum-mechanical particle confined by infinite barriers relevant in semiconductor physics. With this in mind and the interest to tailor waveguides towards a desired spectrum and modal pattern structure in classical structures and nanostructures, it becomes increasingly important to understand the influence of curvature effects in waveguides. In this work, we demonstrate analytically strong curvature effects for the eigenvalue spectrum of the Helmholtz equation with Neumann boundary conditions in cases where the waveguide cross section is a circular sector. It is found that the linear-in-curvature contribution originates from parity symmetry breaking of eigenstates in circular-sector tori and hence vanishes in a torus with a complete circular cross section. The same strong curvature effect is not present in waveguides subject to Dirichlet boundary conditions where curvature contributions contribute to second-order in the curvature only. We demonstrate this finding by considering wave propagation in a circular-sector torus corresponding to Neumann and Dirichlet boundary conditions, respectively. Results for relative eigenfrequency shifts and modes are determined and compared with three-dimensional finite element method results. Good agreement is found between the present analytical method using a combination of differential geometry with perturbation theory and finite element results for a large range of curvature ratios.
Curvature recognition and force generation in phagocytosis
2010-01-01
Background The uptake of particles by actin-powered invagination of the plasma membrane is common to protozoa and to phagocytes involved in the immune response of higher organisms. The question addressed here is how a phagocyte may use geometric cues to optimize force generation for the uptake of a particle. We survey mechanisms that enable a phagocyte to remodel actin organization in response to particles of complex shape. Results Using particles that consist of two lobes separated by a neck, we found that Dictyostelium cells transmit signals concerning the curvature of a surface to the actin system underlying the plasma membrane. Force applied to a concave region can divide a particle in two, allowing engulfment of the portion first encountered. The phagosome membrane that is bent around the concave region is marked by a protein containing an inverse Bin-Amphiphysin-Rvs (I-BAR) domain in combination with an Src homology (SH3) domain, similar to mammalian insulin receptor tyrosine kinase substrate p53. Regulatory proteins enable the phagocyte to switch activities within seconds in response to particle shape. Ras, an inducer of actin polymerization, is activated along the cup surface. Coronin, which limits the lifetime of actin structures, is reversibly recruited to the cup, reflecting a program of actin depolymerization. The various forms of myosin-I are candidate motor proteins for force generation in particle uptake, whereas myosin-II is engaged only in retracting a phagocytic cup after a switch to particle release. Thus, the constriction of a phagocytic cup differs from the contraction of a cleavage furrow in mitosis. Conclusions Phagocytes scan a particle surface for convex and concave regions. By modulating the spatiotemporal pattern of actin organization, they are capable of switching between different modes of interaction with a particle, either arresting at a concave region and applying force in an attempt to sever the particle there, or extending the cup
CURVATURE-DRIFT INSTABILITY FAILS TO GENERATE PULSAR RADIO EMISSION
Kaganovich, Alexander; Lyubarsky, Yuri
2010-10-01
The curvature-drift instability has long been considered as a viable mechanism for pulsar radio emission. We reconsidered this mechanism by finding an explicit solution describing the propagation of short electromagnetic waves in a plasma flow along curved magnetic field lines. We show that even though the waves could be amplified, the amplification factor remains very close to unity; therefore, this mechanism is unable to generate high brightness temperature emission from initial weak fluctuations.
Actin filament curvature biases branching direction
NASA Astrophysics Data System (ADS)
Wang, Evan; Risca, Viviana; Chaudhuri, Ovijit; Chia, Jia-Jun; Geissler, Phillip; Fletcher, Daniel
2012-02-01
Actin filaments are key components of the cellular machinery, vital for a wide range of processes ranging from cell motility to endocytosis. Actin filaments can branch, and essential in this process is a protein complex known as the Arp2/3 complex, which nucleate new ``daughter'' filaments from pre-existing ``mother'' filaments by attaching itself to the mother filament. Though much progress has been made in understanding the Arp2/3-actin junction, some very interesting questions remain. In particular, F-actin is a dynamic polymer that undergoes a wide range of fluctuations. Prior studies of the Arp2/3-actin junction provides a very static notion of Arp2/3 binding. The question we ask is how differently does the Arp2/3 complex interact with a straight filament compared to a bent filament? In this study, we used Monte Carlo simulations of a surface-tethered worm-like chain to explore possible mechanisms underlying the experimental observation that there exists preferential branch formation by the Arp2/3 complex on the convex face of a curved filament. We show that a fluctuation gating model in which Arp2/3 binding to the actin filament is dependent upon a rare high-local-curvature shape fluctuation of the filament is consistent with the experimental data.
Curvature-tuned preparation of nanoliposomes.
Genç, Rükan; Ortiz, Mayreli; O'Sullivan, Ciara K
2009-11-01
Numerous methods have been reported for the preparation of liposomes, many of which, in addition to requiring time-consuming preparative steps and the use of organic solvents, result in heterogeneous liposome populations of incontrollable size. Taking into consideration the phenomenon of spontaneous vesiculation and the theory of curvature, here we present an extremely rapid and simple, solvent-free method for the preparation of monodisperse solutions of highly stable small unilamellar vesicles using both charged and zwitterionic lipids mixed with lyso-palmitoylphosphatidylcholine, exploiting a combination of a rapid pH change followed by a defined period of equilibration. Various experimental parameters and their interactions were evaluated in terms of their effect on resulting liposome size and shape, as well as on liposome stability and size distribution, with transmission electron microscope imaging being used to visualize the formed liposomes, and photon correlation spectroscopy to obtain statistical data on mean diameter and monodispersity of the liposome population. zeta potential measurements also provided information about the interpretation of vesiculation kinetics and liposome stability. The time interval of pH jump, operation temperature, equilibration time, and lipid type were shown to be the determining factors controlling the size, shape, and monodispersity of the liposomes. Buffer type was also found to be important for the long-term storage of the liposomes. Ongoing work is looking at the application of the developed method for encapsulation of bioactive molecules, such as drugs, genetic materials, and enzymes. PMID:19856992
Instability in bacterial populations and the curvature tensor
NASA Astrophysics Data System (ADS)
Melgarejo, Augusto; Langoni, Laura; Ruscitti, Claudia
2016-09-01
In the geometry associated with equilibrium thermodynamics the scalar curvature Rs is a measure of the volume of correlation, and therefore the singularities of Rs indicates the system instabilities. We explore the use of a similar approach to study instabilities in non-equilibrium systems and we choose as a test example, a colony of bacteria. In this regard we follow the proposal made by Obata et al. of using the curvature tensor for studying system instabilities. Bacterial colonies are often found in nature in concentrated biofilms, or other colony types, which can grow into spectacular patterns visible under the microscope. For instance, it is known that a decrease of bacterial motility with density can promote separation into bulk phases of two coexisting densities; this is opposed to the logistic law for birth and death that allows only a single uniform density to be stable. Although this homogeneous configuration is stable in the absence of bacterial interactions, without logistic growth, a density-dependent swim speed v(ρ) leads to phase separation via a spinodal instability. Thus we relate the singularities in the curvature tensor R to the spinodal instability, that is the appearance of regions of different densities of bacteria.
Encoding Gaussian curvature in glassy and elastomeric liquid crystal solids
Mostajeran, Cyrus; Ware, Taylor H.; White, Timothy J.
2016-01-01
We describe shape transitions of thin, solid nematic sheets with smooth, preprogrammed, in-plane director fields patterned across the surface causing spatially inhomogeneous local deformations. A metric description of the local deformations is used to study the intrinsic geometry of the resulting surfaces upon exposure to stimuli such as light and heat. We highlight specific patterns that encode constant Gaussian curvature of prescribed sign and magnitude. We present the first experimental results for such programmed solids, and they qualitatively support theory for both positive and negative Gaussian curvature morphing from flat sheets on stimulation by light or heat. We review logarithmic spiral patterns that generate cone/anti-cone surfaces, and introduce spiral director fields that encode non-localized positive and negative Gaussian curvature on punctured discs, including spherical caps and spherical spindles. Conditions are derived where these cap-like, photomechanically responsive regions can be anchored in inert substrates by designing solutions that ensure compatibility with the geometric constraints imposed by the surrounding media. This integration of such materials is a precondition for their exploitation in new devices. Finally, we consider the radial extension of such director fields to larger sheets using nematic textures defined on annular domains. PMID:27279777
Mészáros, Noémi; Cibulka, Jakub; Mendiburo, Maria Jose; Romanauska, Anete; Schneider, Maren; Köhler, Alwin
2015-01-01
Summary Nuclear pore complexes (NPCs) are selective transport channels embedded in the nuclear envelope. The cylindrical NPC core forms a protein coat lining a highly curved membrane opening and has a basket-like structure appended to the nucleoplasmic side. How NPCs interact with lipids, promoting membrane bending and NPC integrity, is poorly understood. Here we show that the NPC basket proteins Nup1 and Nup60 directly induce membrane curvature by amphipathic helix insertion into the lipid bilayer. In a cell-free system, both Nup1 and Nup60 transform spherical liposomes into highly curved membrane structures. In vivo, high levels of the Nup1/Nup60 amphipathic helices cause deformation of the yeast nuclear membrane, whereas adjacent helical regions contribute to anchoring the basket to the NPC core. Basket amphipathic helices are functionally linked to distinct transmembrane nucleoporins of the NPC core, suggesting a key contribution to the membrane remodeling events that underlie NPC assembly. PMID:25942622
A high-resolution regional reanalysis for Europe
NASA Astrophysics Data System (ADS)
Ohlwein, C.
2015-12-01
Reanalyses gain more and more importance as a source of meteorological information for many purposes and applications. Several global reanalyses projects (e.g., ERA, MERRA, CSFR, JMA9) produce and verify these data sets to provide time series as long as possible combined with a high data quality. Due to a spatial resolution down to 50-70km and 3-hourly temporal output, they are not suitable for small scale problems (e.g., regional climate assessment, meso-scale NWP verification, input for subsequent models such as river runoff simulations). The implementation of regional reanalyses based on a limited area model along with a data assimilation scheme is able to generate reanalysis data sets with high spatio-temporal resolution. Within the Hans-Ertel-Centre for Weather Research (HErZ), the climate monitoring branch concentrates efforts on the assessment and analysis of regional climate in Germany and Europe. In joint cooperation with DWD (German Meteorological Service), a high-resolution reanalysis system based on the COSMO model has been developed. The regional reanalysis for Europe matches the domain of the CORDEX EURO-11 specifications, albeit at a higher spatial resolution, i.e., 0.055° (6km) instead of 0.11° (12km) and comprises the assimilation of observational data using the existing nudging scheme of COSMO complemented by a special soil moisture analysis with boundary conditions provided by ERA-Interim data. The reanalysis data set covers the past 20 years. Extensive evaluation of the reanalysis is performed using independent observations with special emphasis on precipitation and high-impact weather situations indicating a better representation of small scale variability. Further, the evaluation shows an added value of the regional reanalysis with respect to the forcing ERA Interim reanalysis and compared to a pure high-resolution dynamical downscaling approach without data assimilation.
Evaluation of a High-Resolution Regional Reanalysis for Europe
NASA Astrophysics Data System (ADS)
Ohlwein, C.; Wahl, S.; Keller, J. D.; Bollmeyer, C.
2014-12-01
Reanalyses gain more and more importance as a source of meteorological information for many purposes and applications. Several global reanalyses projects (e.g., ERA, MERRA, CSFR, JMA9) produce and verify these data sets to provide time series as long as possible combined with a high data quality. Due to a spatial resolution down to 50-70km and 3-hourly temporal output, they are not suitable for small scale problems (e.g., regional climate assessment, meso-scale NWP verification, input for subsequent models such as river runoff simulations). The implementation of regional reanalyses based on a limited area model along with a data assimilation scheme is able to generate reanalysis data sets with high spatio-temporal resolution. Within the Hans-Ertel-Centre for Weather Research (HErZ), the climate monitoring branch concentrates efforts on the assessment and analysis of regional climate in Germany and Europe. In joint cooperation with DWD (German Meteorological Service), a high-resolution reanalysis system based on the COSMO model has been developed. The regional reanalysis for Europe matches the domain of the CORDEX EURO-11 specifications, albeit at a higher spatial resolution, i.e., 0.055° (6km) instead of 0.11° (12km) and comprises the assimilation of observational data using the existing nudging scheme of COSMO complemented by a special soil moisture analysis with boundary conditions provided by ERA-Interim data. The reanalysis data set covers 6 years (2007-2012) and is currently extended to 16 years. Extensive evaluation of the reanalysis is performed using independent observations with special emphasis on precipitation and high-impact weather situations indicating a better representation of small scale variability. Further, the evaluation shows an added value of the regional reanalysis with respect to the forcing ERA Interim reanalysis and compared to a pure high-resolution dynamical downscaling approach without data assimilation.
Curvature-undulation coupling as a basis for curvature sensing and generation in bilayer membranes.
Bradley, Ryan P; Radhakrishnan, Ravi
2016-08-30
We present coarse-grained molecular dynamics simulations of the epsin N-terminal homology domain interacting with a lipid bilayer and demonstrate a rigorous theoretical formalism and analysis method for computing the induced curvature field in varying concentrations of the protein in the dilute limit. Our theory is based on the description of the height-height undulation spectrum in the presence of a curvature field. We formulated an objective function to compare the acquired undulation spectrum from the simulations to that of the theory. We recover the curvature field parameters by minimizing the objective function even in the limit where the protein-induced membrane curvature is of the same order as the amplitude due to thermal undulations. The coupling between curvature and undulations leads to significant predictions: (i) Under dilute conditions, the proteins can sense a site of spontaneous curvature at distances much larger than their size; (ii) as the density of proteins increases the coupling focuses and stabilizes the curvature field to the site of the proteins; and (iii) the mapping of the protein localization and the induction of a stable curvature is a cooperative process that can be described through a Hill function. PMID:27531962
A new algorithm for evaluating 3D curvature and curvature gradient for improved fracture detection
NASA Astrophysics Data System (ADS)
Di, Haibin; Gao, Dengliang
2014-09-01
In 3D seismic interpretation, both curvature and curvature gradient are useful seismic attributes for structure characterization and fault detection in the subsurface. However, the existing algorithms are computationally intensive and limited by the lateral resolution for steeply-dipping formations. This study presents new and robust volume-based algorithms that evaluate both curvature and curvature gradient attributes more accurately and effectively. The algorithms first instantaneously fit a local surface to seismic data and then compute attributes using the spatial derivatives of the built surface. Specifically, the curvature algorithm constructs a quadratic surface by using a rectangle 9-node grid cell, whereas the curvature gradient algorithm builds a cubic surface by using a diamond 13-node grid cell. A dip-steering approach based on 3D complex seismic trace analysis is implemented to enhance the accuracy of surface construction and to reduce computational time. Applications to two 3D seismic surveys demonstrate the accuracy and efficiency of the new curvature and curvature gradient algorithms for characterizing faults and fractures in fractured reservoirs.
Gravitropic curvature of maize roots is not preceded by rootcap asymmetry
NASA Technical Reports Server (NTRS)
Sack, F. D.; Hasenstein, K. H.; Blair, A.
1990-01-01
We tested whether the first response to gravistimulation is an asymmetry in the root tip that results from differential growth of the rootcap itself. The displacement of markers on the rootcap surface of maize (Zea mays L. cv. Merit) roots was quantified from videotaped images using customized software. The method was sensitive enough to detect marker displacements down to 15 microns and root curvature as early as 8 min after gravistimulation. No differential growth of the upper and lower sides of the cap occurred before or during root curvature. Fewer than a third of all gravistimulated roots developed an asymmetrical outline of the root tip after curvature had started, and this asymmetry did not occur in the rootcap itself. Our data support the view that the regions of gravitropic sensing and curvature are spatially separate during all phases of gravitropism in maize roots.
Curvature constraints from large scale structure
NASA Astrophysics Data System (ADS)
Di Dio, Enea; Montanari, Francesco; Raccanelli, Alvise; Durrer, Ruth; Kamionkowski, Marc; Lesgourgues, Julien
2016-06-01
We modified the CLASS code in order to include relativistic galaxy number counts in spatially curved geometries; we present the formalism and study the effect of relativistic corrections on spatial curvature. The new version of the code is now publicly available. Using a Fisher matrix analysis, we investigate how measurements of the spatial curvature parameter ΩK with future galaxy surveys are affected by relativistic effects, which influence observations of the large scale galaxy distribution. These effects include contributions from cosmic magnification, Doppler terms and terms involving the gravitational potential. As an application, we consider angle and redshift dependent power spectra, which are especially well suited for model independent cosmological constraints. We compute our results for a representative deep, wide and spectroscopic survey, and our results show the impact of relativistic corrections on spatial curvature parameter estimation. We show that constraints on the curvature parameter may be strongly biased if, in particular, cosmic magnification is not included in the analysis. Other relativistic effects turn out to be subdominant in the studied configuration. We analyze how the shift in the estimated best-fit value for the curvature and other cosmological parameters depends on the magnification bias parameter, and find that significant biases are to be expected if this term is not properly considered in the analysis.
Lipids, curvature, and nano-medicine*
Mouritsen, Ole G
2011-01-01
The physical properties of the lamellar lipid-bilayer component of biological membranes are controlled by a host of thermodynamic forces leading to overall tensionless bilayers with a conspicuous lateral pressure profile and build-in curvature-stress instabilities that may be released locally or globally in terms of morphological changes. In particular, the average molecular shape and the propensity of the different lipid and protein species for forming non-lamellar and curved structures are a source of structural transitions and control of biological function. The effects of different lipids, sterols, and proteins on membrane structure are discussed and it is shown how one can take advantage of the curvature-stress modulations brought about by specific molecular agents, such as fatty acids, lysolipids, and other amphiphilic solutes, to construct intelligent drug-delivery systems that function by enzymatic triggering via curvature. Practical applications: The simple concept of lipid molecular shape and how it impacts on the structure of lipid aggregates, in particular the curvature and curvature stress in lipid bilayers and liposomes, can be exploited to construct liposome-based drug-delivery systems, e.g., for use as nano-medicine in cancer therapy. Non-lamellar-forming lysolipids and fatty acids, some of which may be designed to be prodrugs, can be created by phospholipase action in diseased tissues thereby providing for targeted drug release and proliferation of molecular entities with conical shape that break down the permeability barrier of the target cells and may hence enhance efficacy. PMID:22164124
High Plains Regional Ground-water Study web site
Qi, Sharon L.
2000-01-01
Now available on the Internet is a web site for the U.S. Geological Survey's (USGS) National Water-Quality Assessment (NAWQA) Program- High Plains Regional Ground-Water Study. The purpose of the web site is to provide public access to a wide variety of information on the USGS investigation of the ground-water resources within the High Plains aquifer system. Typical pages on the web site include the following: descriptions of the High Plains NAWQA, the National NAWQA Program, the study-area setting, current and past activities, significant findings, chemical and ancillary data (which can be downloaded), listing and access to publications, links to other sites about the High Plains area, and links to other web sites studying High Plains ground-water resources. The High Plains aquifer is a regional aquifer system that underlies 174,000 square miles in parts of eight States (Colorado, Kansas, Nebraska, New Mexico, Oklahoma, South Dakota, Texas, and Wyoming). Because the study area is so large, the Internet is an ideal way to provide project data and information on a near real-time basis. The web site will be a collection of living documents where project data and information are updated as it becomes available throughout the life of the project. If you have an interest in the High Plains area, you can check this site periodically to learn how the High Plains NAWQA activities are progressing over time and access new data and publications as they become available.
Stagnation region heat transfer augmentation at very high turbulence levels
Kingery, Joseph E.; Ames, Forrest E.
2016-08-01
Current land-based gas turbines are growing in size producing higher approach flow Reynolds numbers at the leading edge of turbine nozzles. These vanes are subjected to high intensity large scale turbulence. This present paper reports on the research which significantly expands the parameter range for stagnation region heat transfer augmenta-tion due to high intensity turbulence. Heat transfer measurements were acquired over two constant heat flux test surfaces with large diameter leading edges (10.16 cm and 40.64 cm). The test surfaces were placed downstream from a new high intensity (17.4%) mock combustor and tested over an eight to one range inmore » approach flow Reynolds number for each test surface. Stagnation region heat transfer augmentation for the smaller (ReD = 15,625–125,000) and larger (ReD = 62,500–500,000) leading edge regions ranged from 45% to 81% and 80% to 136%, respectively. Furthermore, these data also include heat transfer distributions over the full test surface compared with the earlier data acquired at six additional inlet turbulence conditions. These surfaces exhibit continued but more moderate acceleration downstream from the stagnation regions and these data are expected to be useful in testing bypass transition predictive approaches. This database will be useful to gas turbine heat transfer design engineers. [DOI: 10.1115/1.4032677]« less
Zhao, Chunyu; Burge, James H
2013-12-16
Zernike polynomials are an orthonormal set of scalar functions over a circular domain, and are commonly used to represent wavefront phase or surface irregularity. In optical testing, slope or curvature of a surface or wavefront is sometimes measured instead, from which the surface or wavefront map is obtained. Previously we derived an orthonormal set of vector polynomials that fit to slope measurement data and yield the surface or wavefront map represented by Zernike polynomials. Here we define a 3-element curvature vector used to represent the second derivatives of a continuous surface, and derive a set of orthonormal curvature basis functions that are written in terms of Zernike polynomials. We call the new curvature functions the C polynomials. Closed form relations for the complete basis set are provided, and we show how to determine Zernike surface coefficients from the curvature data as represented by the C polynomials. PMID:24514717
Renormalization of curvature elastic constants for elastic and fluid membranes
NASA Astrophysics Data System (ADS)
Ami, S.; Kleinert, H.
1987-02-01
We study the fluctuations of membranes with area and curvature elasticity and calculate the renormalization of the curvature elastic constants due to thermal fluctuations. For the mean curvature elastic constant the result is the same as obtained previously for “ideal membranes” which resist only to curvature deformations. The renormalization of the gaussian curvature, on the other hand, depends on the elastic contants. In an incompressible membrane, it is five times weaker than in an ideal membrane.
Membrane tension controls the assembly of curvature-generating proteins
Simunovic, Mijo; Voth, Gregory A.
2015-01-01
Proteins containing a Bin/Amphiphysin/Rvs (BAR) domain regulate membrane curvature in the cell. Recent simulations have revealed that BAR proteins assemble into linear aggregates, strongly affecting membrane curvature and its in-plane stress profile. Here, we explore the opposite question: do mechanical properties of the membrane impact protein association? By using coarse-grained molecular dynamics simulations, we show that increased surface tension significantly impacts the dynamics of protein assembly. While tensionless membranes promote a rapid formation of long-living linear aggregates of N-BAR proteins, increase in tension alters the geometry of protein association. At high tension, protein interactions are strongly inhibited. Increasing surface density of proteins leads to a wider range of protein association geometries, promoting the formation of meshes, which can be broken apart with membrane tension. Our work indicates that surface tension may play a key role in recruiting proteins to membrane-remodelling sites in the cell. PMID:26008710
Curvature effects on carbon nanomaterials: Exohedral versus endhohedral supercapacitors
Huang, J; Sumpter, B. G.; Meunier, V.; Yushin, G.; Portet, C.; Gogotsi, Y.
2011-01-31
Capacitive energy storage mechanisms in nanoporous carbon supercapacitors hinge on endohedral interactions in carbon materials with macro-, meso-, and micropores that have negative surface curvature. In this article, we show that because of the positive curvature found in zero-dimensional carbon onions or one-dimensional carbon nanotube arrays, exohedral interactions cause the normalized capacitance to increase with decreasing particle size or tube diameter, in sharp contrast to the behavior of nanoporous carbon materials. This finding is in good agreement with the trend of recent experimental data. Our analysis suggests that electrical energy storage can be improved by exploiting the highly curved surfaces of carbon nanotube arrays with diameters on the order of 1 nm.
Curvature effects in carbon nanomaterials: Exohedral versus endohedral supercapacitors
Huang, Jingsong; Sumpter, Bobby G; Meunier, Vincent; Gogotsi, Yury G.; Yushin, Gleb; Portet, Cristelle
2010-01-01
Capacitive energy storage mechanisms in nanoporous carbon supercapacitors hinge on endohedral interactions in carbon materials with macro-, meso-, and micropores that have negative surface curvature. In this article, we show that because of the positive curvature found in zero-dimensional carbon onions or one-dimensional carbon nanotube arrays, exohedral interactions cause the normalized capacitance to increase with decreasing particle size or tube diameter, in sharp contrast to the behavior of nanoporous carbon materials. This finding is in good agreement with the trend of recent experimental data. Our analysis suggests that electrical energy storage can be improved by exploiting the highly curved surfaces of carbon nanotube arrays with diameters on the order of 1 nm.
Control of repeat protein curvature by computational protein design
Park, Keunwan; Shen, Betty W.; Parmeggiani, Fabio; Huang, Po-Ssu; Stoddard, Barry L.; Baker, David
2014-01-01
Shape complementarity is an important component of molecular recognition, and the ability to precisely adjust the shape of a binding scaffold to match a target of interest would greatly facilitate the creation of high affinity protein reagents and therapeutics. Here we describe a general approach to control the shape of the binding surface on repeat protein scaffolds, and apply it to leucine rich repeat proteins. First, a set of self-compatible building block modules are designed that when polymerized each generate surfaces with unique but constant curvatures. Second, a set of junction modules that connect the different building blocks are designed. Finally, new proteins with custom designed shapes are generated by appropriately combining building block and junction modules. Crystal structures of the designs illustrate the power of the approach in controlling repeat protein curvature. PMID:25580576
DNA Origami with Complex Curvatures in Three-Dimensional Space
Han, Dongran; Pal, Suchetan; Nangreave, Jeanette; Deng, Zhengtao; Liu, Yan; Yan, Hao
2011-04-14
We present a strategy to design and construct self-assembling DNA nanostructures that define intricate curved surfaces in three-dimensional (3D) space using the DNA origami folding technique. Double-helical DNA is bent to follow the rounded contours of the target object, and potential strand crossovers are subsequently identified. Concentric rings of DNA are used to generate in-plane curvature, constrained to 2D by rationally designed geometries and crossover networks. Out-of-plane curvature is introduced by adjusting the particular position and pattern of crossovers between adjacent DNA double helices, whose conformation often deviates from the natural, B-form twist density. A series of DNA nanostructures with high curvature—such as 2D arrangements of concentric rings and 3D spherical shells, ellipsoidal shells, and a nanoflask—were assembled.
High dispersion observations of selected regions in the Orion Nebula
NASA Astrophysics Data System (ADS)
Boeshaar, G. O.; Harvel, C. A.; Mallama, A. D.; Perry, P. M.; Thompson, R. W.; Turnrose, B.
High resolution spectral observations were made of several regions of the Orion Nebula near theta (2) Ori A using the IUE. The positions were selected using a moderate spatial resolution map from a previous low dispersion IUE survery of this section of the nebula. With the SWP and LWR cameras, 28 pectra were obtained of the bright bar, three Taylor-Munch cloudlets, and several surrounding locations. Emission lines of He, C, N, O, Mg, and Si allow a characterization of these cloudlets and of the gas in and around the bar. Small aperture observations provide radial velocity information for the ultraviolet emission of these features. These data show ionization variations from region to region and are suggestive of stellar wind interactions between the cloudlets and theta(2) Ori A.
Curvature corrections and Kac Moody compatibility conditions
NASA Astrophysics Data System (ADS)
Damour, Thibault; Hanany, Amihay; Henneaux, Marc; Kleinschmidt, Axel; Nicolai, Hermann
2006-10-01
We study possible restrictions on the structure of curvature corrections to gravitational theories in the context of their corresponding Kac Moody algebras, following the initial work on E 10 in Damour and Nicolai [Class Quant Grav 22:2849 (2005)]. We first emphasize that the leading quantum corrections of M-theory can be naturally interpreted in terms of (non-gravity) fundamental weights of E 10. We then heuristically explore the extent to which this remark can be generalized to all over-extended algebras by determining which curvature corrections are compatible with their weight structure, and by comparing these curvature terms with known results on the quantum corrections for the corresponding gravitational theories.
Superintegrable systems on spaces of constant curvature
NASA Astrophysics Data System (ADS)
Gonera, Cezary; Kaszubska, Magdalena
2014-07-01
Construction and classification of two-dimensional (2D) superintegrable systems (i.e. systems admitting, in addition to two global integrals of motion guaranteeing the Liouville integrability, the third global and independent one) defined on 2D spaces of constant curvature and separable in the so-called geodesic polar coordinates are presented. The method proposed is applicable to any value of curvature including the case of Euclidean plane, sphere and hyperbolic plane. The main result is a generalization of Bertrand's theorem on 2D spaces of constant curvature and covers most of the known separable and superintegrable models on such spaces (in particular, the so-called Tremblay-Turbine-Winternitz (TTW) and Post-Winternitz (PW) models which have recently attracted some interest).
Extrinsic and intrinsic curvatures in thermodynamic geometry
NASA Astrophysics Data System (ADS)
Hosseini Mansoori, Seyed Ali; Mirza, Behrouz; Sharifian, Elham
2016-08-01
We investigate the intrinsic and extrinsic curvatures of a certain hypersurface in thermodynamic geometry of a physical system and show that they contain useful thermodynamic information. For an anti-Reissner-Nordström-(A)de Sitter black hole (Phantom), the extrinsic curvature of a constant Q hypersurface has the same sign as the heat capacity around the phase transition points. The intrinsic curvature of the hypersurface can also be divergent at the critical points but has no information about the sign of the heat capacity. Our study explains the consistent relationship holding between the thermodynamic geometry of the KN-AdS black holes and those of the RN (J-zero hypersurface) and Kerr black holes (Q-zero hypersurface) ones [1]. This approach can easily be generalized to an arbitrary thermodynamic system.
On the curvature effect of thin membranes
NASA Astrophysics Data System (ADS)
Wang, Duo; Jiao, Xiangmin; Conley, Rebecca; Glimm, James
2013-01-01
We investigate the curvature effect of a thin, curved elastic interface that separates two subdomains and exerts a pressure due to a curvature effect. This pressure, which we refer to as interface pressure, is similar to the surface tension in fluid mechanics. It is important in some applications, such as the canopy of parachutes, biological membranes of cells, balloons, airbags, etc., as it partially balances a pressure jump between the two sides of an interface. In this paper, we show that the interface pressure is equal to the trace of the matrix product of the curvature tensor and the Cauchy stress tensor in the tangent plane. We derive the theory for interfaces in both 2-D and 3-D, and present numerical discretizations for computing the quality over triangulated surfaces.
Geometrical Membrane Curvature as an Allosteric Regulator of Membrane Protein Structure and Function
Tonnesen, Asger; Christensen, Sune M.; Tkach, Vadym; Stamou, Dimitrios
2014-01-01
Transmembrane proteins are embedded in cellular membranes of varied lipid composition and geometrical curvature. Here, we studied for the first time the allosteric effect of geometrical membrane curvature on transmembrane protein structure and function. We used single-channel optical analysis of the prototypic transmembrane β-barrel α-hemolysin (α-HL) reconstituted on immobilized single small unilamellar liposomes of different diameter and therefore curvature. Our data demonstrate that physiologically abundant geometrical membrane curvatures can enforce a dramatic allosteric regulation (1000-fold inhibition) of α-HL permeability. High membrane curvatures (1/diameter ∼1/40 nm−1) compressed the effective pore diameter of α-HL from 14.2 ± 0.8 Å to 11.4 ± 0.6 Å. This reduction in effective pore area (∼40%) when combined with the area compressibility of α-HL revealed an effective membrane tension of ∼50 mN/m and a curvature-imposed protein deformation energy of ∼7 kBT. Such substantial energies have been shown to conformationally activate, or unfold, β-barrel and α-helical transmembrane proteins, suggesting that membrane curvature could likely regulate allosterically the structure and function of transmembrane proteins in general. PMID:24411252
Using hilltop curvature to derive the spatial distribution of erosion rates
NASA Astrophysics Data System (ADS)
Hurst, Martin D.; Mudd, Simon M.; Walcott, Rachel; Attal, Mikael; Yoo, Kyungsoo
2012-06-01
Erosion rates dictate the morphology of landscapes, and therefore quantifying them is a critical part of many geomorphic studies. Methods to directly measure erosion rates are expensive and time consuming, whereas topographic analysis facilitates prediction of erosion rates rapidly and over large spatial extents. If hillslope sediment flux is nonlinearly dependent on slope then the curvature of hilltops will be linearly proportional to erosion rates. In this contribution we develop new techniques to extract hilltop networks and sample their adjacent hillslopes in order to test the utility of hilltop curvature for estimating erosion rates using high-resolution (1 m) digital elevation data. Published and new cosmogenic radionuclide analyses in the Feather River basin, California, suggest that erosion rates vary by over an order of magnitude (10 to 250 mm kyr-1). Hilltop curvature increases with erosion rates, allowing calibration of the hillslope sediment transport coefficient, which controls the relationship between gradient and sediment flux. Having constraints on sediment transport efficiency allows estimation of erosion rates throughout the landscape by mapping the spatial distribution of hilltop curvature. Additionally, we show that hilltop curvature continues to increase with rising erosion rates after gradient-limited hillslopes have emerged. Hence hilltop curvature can potentially reflect higher erosion rates than can be predicted by hillslope gradient, providing soil production on hilltops can keep pace with erosion. Finally, hilltop curvature can be used to estimate erosion rates in landscapes undergoing a transient adjustment to changing boundary conditions if the response timescale of hillslopes is short relative to channels.
Dymond, Marcus K
2016-08-01
Several theories of phospholipid homeostasis have postulated that cells regulate the molecular composition of their bilayer membranes, such that a common biophysical membrane parameter is under homeostatic control. Two commonly cited theories are the intrinsic curvature hypothesis, which states that cells control membrane curvature elastic stress, and the theory of homeoviscous adaptation, which postulates cells control acyl chain packing order (membrane order). In this paper, we present evidence from data-driven modelling studies that these two theories correlate in vivo. We estimate the curvature elastic stress of mammalian cells to be 4-7 × 10(-12) N, a value high enough to suggest that in mammalian cells the preservation of membrane order arises through a mechanism where membrane curvature elastic stress is controlled. These results emerge from analysing the molecular contribution of individual phospholipids to both membrane order and curvature elastic stress in nearly 500 cellular compositionally diverse lipidomes. Our model suggests that the de novo synthesis of lipids is the dominant mechanism by which cells control curvature elastic stress and hence membrane order in vivo These results also suggest that cells can increase membrane curvature elastic stress disproportionately to membrane order by incorporating polyunsaturated fatty acids into lipids. PMID:27534697
Hybrid curvature and modal wavefront sensor
NASA Astrophysics Data System (ADS)
Dong, Shihao; Haist, Tobias; Dietrich, Tom; Osten, Wolfgang
2014-09-01
The crosstalk effect considerably limits the capability of holography-based modal wavefront sensing (HMWS) when measuring wavefronts with large aberrations. In this contribution, we introduce a curvature-based measurement technique into HMWS to extend the dynamic range and the sensitivity of HMWS via a compact holographic design. If the input aberrations are large, the dominating aberration modes are first detected via curvature sensing and compensated using a wavefront correcting device, e.g. a membrane mirror. The system then switches to HMWS to obtain better sensitivity and accuracy with reduced aberrations. Different approaches for the reconstruction of the wavefront have been tested and extensive simulations for different aberrations have been analyzed.
Scaling of curvature in subcritical gravitational collapse
NASA Astrophysics Data System (ADS)
Garfinkle, David; Duncan, G. Comer
1998-09-01
We perform numerical simulations of the gravitational collapse of a spherically symmetric scalar field. For those data that just barely do not form black holes we find the maximum curvature at the position of the central observer. We find a scaling relation between this maximum curvature and distance from the critical solution. The scaling relation is analogous to that found by Choptuik for the black hole mass for those data that do collapse to form black holes. We also find a periodic wiggle in the scaling exponent.
NASTRAN modifications for recovering strains and curvatures
NASA Technical Reports Server (NTRS)
Hennrich, C. W.
1975-01-01
Modifications to the NASTRAN structural analysis computer program are described. The modifications allow the recovery of strain and curvature data for the general two-dimensional elements, in addition to the usual stress data. Option features allow the transformation of the strain/curvature (or stress) data to a common coordinate system and representation at the grid points of the structural model rather than at the conventional element center locations. Usage information is provided which will allow present users of NASTRAN to easily utilize the new capability.
Modulus stabilization in higher curvature dilaton gravity
NASA Astrophysics Data System (ADS)
Choudhury, Sayantan; Mitra, Joydip; SenGupta, Soumitra
2014-08-01
We propose a framework of modulus stabilization in two brane warped geometry scenario in presence of higher curvature gravity and dilaton in bulk space-time. In the prescribed setup we study various features of the stabilized potential for the modulus field, generated by a bulk scalar degrees of freedom with quartic interactions localized on the two 3-branes placed at the orbifold fixed points. We determine the parameter space for the gravidilaton and Gauss-Bonnet couplings required to stabilize the modulus in such higher curvature dilaton gravity setup.
A methodology for quantifying seated lumbar curvatures.
Leitkam, Samuel T; Bush, Tamara Reid; Li, Mingfei
2011-11-01
To understand the role seating plays in the support of posture and spinal articulation, it is necessary to study the interface between a human and the seat. However, a method to quantify lumbar curvature in commercially available unmodified seats does not currently exist. This work sought to determine if the lumbar curvature for normal ranges of seated posture could be documented by using body landmarks located on the anterior portion of the body. The development of such a methodology will allow researchers to evaluate spinal articulation of a seated subject while in standard, commercially available seats and chairs. Anterior measurements of boney landmarks were used to quantify the relative positions of the ribcage and pelvis while simultaneous posterior measurements were made of lumbar curvature. The relationship between the anterior and the posterior measures was compared. The predictive capacity of this approach was evaluated by determining linear and second-order regressions for each of the four postures across all subjects and conducting a leave-one-out cross validation. The relationships between the anterior and posterior measures were approximated by linear and second-order polynomial regressions (r(2 ) = 0.829, 0.935 respectively) across all postures. The quantitative analysis showed that openness had a significant relationship with lumbar curvature, and a first-order regression was superior to a second-order regression. Average standard errors in the prediction were 5.9° for the maximum kyphotic posture, 9.9° for the comfortable posture, 12.8° for the straight and tall, and 22.2° for the maximum lordotic posture. These results show predictions of lumbar curvature are possible in seated postures by using a motion capture system and anterior measures. This method of lumbar curvature prediction shows potential for use in the assessment of seated spinal curvatures and the corresponding design of seating to accommodate those curvatures; however
CIRCULAR POLARIZATION IN PULSARS DUE TO CURVATURE RADIATION
Gangadhara, R. T.
2010-02-10
The beamed radio emission from relativistic plasma (particles or bunches), constrained to move along the curved trajectories, occurs in the direction of velocity. We have generalized the coherent curvature radiation model to include the detailed geometry of the emission region in pulsar magnetosphere and deduced the polarization state in terms of Stokes parameters. By considering both the uniform and modulated emissions, we have simulated a few typical pulse profiles. The antisymmetric type of circular polarization survives only when there is modulation or discrete distribution in the emitting sources. Our model predicts a correlation between the polarization angle swing and sign reversal of circular polarization as a geometric property of the emission process.
A high resolution regional paleoclimate experiment over the Iberian Peninsula
NASA Astrophysics Data System (ADS)
Gomez-Navarro, J. J.; Montavez, J. P.; Jerez, S.; Jimenez-Guerrero, P.; Garcia-Valero, J. A.; Gonzalez-Rouco, J. F.
2009-04-01
During the last years the use of paleoclimate simulations with models of different complexity has become an usual tool in paleoclimate studies. Progress in understanding climate variability leans on simulation and reconstruction efforts. Exercises blending both approaches present a great potential for answering questions relevant for both the simulation and reconstruction of past climate, and depend on the specific peculiarities of proxies and methods involved in climate reconstructions, as well as on the realism and limitations of model simulations. Most of paleoclimate integrations available in the literature covering the last millennium have been performed with relative rough resolution which does not allow to analyze regional climate features that can be of interest in the context of proxies evidence. In this work we present a new high resolution (30 km) regional climate simulation over the Iberian Peninsula of the last five centuries and two extensions to the future for the A2 and B2 SRES scenarios. The regional simulations were performed with a climate version of the MM5 model coupled to the Noah LSM. The driving conditions used follow the Erik1 experiment, performed with the ECHO-G global circulation model. The results indicate that the seasonal modes of variation for near surface air temperature and precipitation obtained within the regional paleoclimate experiment are consistent with the obtained using the observational databases and equivalent to regional climate integrations driven by reanalysis data. On the other hand, the main modes of variation show strong signals in historical periods such as the Maunder and Dalton Minimum. Finally, some preliminary comparisons between the global and the regional model against tree ring temperature reconstructions are also reported in this contribution.
Curvature-dependent excitation propagation in cultured cardiac tissue
NASA Astrophysics Data System (ADS)
Kadota, S.; Kay, M. W.; Magome, N.; Agladze, K.
2012-02-01
The geometry of excitation wave front may play an important role on the propagation block and spiral wave formation. The wave front which is bent over the critical value due to interaction with the obstacles may partially cease to propagate and appearing wave breaks evolve into rotating waves or reentry. This scenario may explain how reentry spontaneously originates in a heart. We studied highly curved excitation wave fronts in the cardiac tissue culture and found that in the conditions of normal, non-inhibited excitability the curvature effects do not play essential role in the propagation. Neither narrow isthmuses nor sharp corners of the obstacles, being classical objects for production of extremely curved wave front, affect non-inhibited wave propagation. The curvature-related phenomena of the propagation block and wave detachment from the obstacle boundary were observed only after partial suppression of the sodium channels with Lidocaine. Computer simulations confirmed the experimental observations. The explanation of the observed phenomena refers to the fact that the heart tissue is made of finite size cells so that curvature radii smaller than the cardiomyocyte size loses sense, and in non-inhibited tissue the single cell is capable to transmit excitation to its neighbors.
High Spatial Resolution Fe XII Observations of Solar Active Regions
NASA Astrophysics Data System (ADS)
Testa, Paola; De Pontieu, Bart; Hansteen, Viggo
2016-08-01
We use UV spectral observations of active regions with the Interface Region Imaging Spectrograph (IRIS) to investigate the properties of the coronal Fe xii 1349.4 Å emission at unprecedented high spatial resolution (∼0.33″). We find that by using appropriate observational strategies (i.e., long exposures, lossless compression), Fe xii emission can be studied with IRIS at high spatial and spectral resolution, at least for high-density plasma (e.g., post-flare loops and active region moss). We find that upper transition region (TR; moss) Fe xii emission shows very small average Doppler redshifts ({v}{{D}} ∼ 3 km s‑1) as well as modest non-thermal velocities (with an average of ∼24 km s‑1 and the peak of the distribution at ∼15 km s‑1). The observed distribution of Doppler shifts appears to be compatible with advanced three-dimensional radiative MHD simulations in which impulsive heating is concentrated at the TR footpoints of a hot corona. While the non-thermal broadening of Fe xii 1349.4 Å peaks at similar values as lower resolution simultaneous Hinode Extreme Ultraviolet Imaging Spectrometer (EIS) measurements of Fe xii 195 Å, IRIS observations show a previously undetected tail of increased non-thermal broadening that might be suggestive of the presence of subarcsecond heating events. We find that IRIS and EIS non-thermal line broadening measurements are affected by instrumental effects that can only be removed through careful analysis. Our results also reveal an unexplained discrepancy between observed 195.1/1349.4 Å Fe xii intensity ratios and those predicted by the CHIANTI atomic database.
High Spatial Resolution Fe XII Observations of Solar Active Regions
NASA Astrophysics Data System (ADS)
Testa, Paola; De Pontieu, Bart; Hansteen, Viggo
2016-08-01
We use UV spectral observations of active regions with the Interface Region Imaging Spectrograph (IRIS) to investigate the properties of the coronal Fe xii 1349.4 Å emission at unprecedented high spatial resolution (˜0.33″). We find that by using appropriate observational strategies (i.e., long exposures, lossless compression), Fe xii emission can be studied with IRIS at high spatial and spectral resolution, at least for high-density plasma (e.g., post-flare loops and active region moss). We find that upper transition region (TR; moss) Fe xii emission shows very small average Doppler redshifts ({v}{{D}} ˜ 3 km s‑1) as well as modest non-thermal velocities (with an average of ˜24 km s‑1 and the peak of the distribution at ˜15 km s‑1). The observed distribution of Doppler shifts appears to be compatible with advanced three-dimensional radiative MHD simulations in which impulsive heating is concentrated at the TR footpoints of a hot corona. While the non-thermal broadening of Fe xii 1349.4 Å peaks at similar values as lower resolution simultaneous Hinode Extreme Ultraviolet Imaging Spectrometer (EIS) measurements of Fe xii 195 Å, IRIS observations show a previously undetected tail of increased non-thermal broadening that might be suggestive of the presence of subarcsecond heating events. We find that IRIS and EIS non-thermal line broadening measurements are affected by instrumental effects that can only be removed through careful analysis. Our results also reveal an unexplained discrepancy between observed 195.1/1349.4 Å Fe xii intensity ratios and those predicted by the CHIANTI atomic database.
Testing the regionalization of a SVAT model for a region with high observation density
NASA Astrophysics Data System (ADS)
Eiermann, Sven; Thies, Boris; Bendix, Jörg
2014-05-01
The variable soil moisture is an important quantity in weather and climate investigations, because it has an essential influence on the energy exchange between the land surface and the atmosphere. However the recording of soil moisture in high spatio-temporal resolution is problematic. The planned Tandem-L mission of the German Aerospace Center (DLR) with an innovative L-band radar on board provides the opportunity to get daily soil moisture data at a spatial resolution of 50 meters. Within the Helmholtz Alliance Remote Sensing and Earth System Dynamics this data is planned to be used to regionalize a Soil Vegetation Atmosphere Transfer Model, in order to analyze the energy flux and the gas exchange and to improve the prediction of the water exchange between soil, vegetation and atmosphere. As investigation areas selected regions of the TERENO (TERrestrial ENviromental Observatoria) test sites and, later on, a region in South Ecuador will be used, for which data for the model initialization and validation are available. The reason for testing the method for the TERENO test sites first is the good data basis as a result of the already established high observation density there. The poster will present the methods being used for the model adaptation for the TERENO test sites and discuss the improvements achieved by these methods.
Photon Drag Effect due to Berry Curvature
NASA Astrophysics Data System (ADS)
Kurosawa, Hiroyuki; Sawada, Kei; Ohno, Seigo
2016-08-01
A theoretical investigation reveals that the photon drag effect (PDE) is induced in a grating slab with deformation by the Berry curvature in phase space. It drifts the momentum of light, and gives asymmetric PDE signals in momentum space. Large PDE signals are observed even near the Γ point. This characteristic agrees well with our theoretical results.
Constraining inverse curvature gravity with supernovae
Mena, Olga; Santiago, Jose; Weller, Jochen; /University Coll., London /Fermilab
2005-10-01
We show that the current accelerated expansion of the Universe can be explained without resorting to dark energy. Models of generalized modified gravity, with inverse powers of the curvature can have late time accelerating attractors without conflicting with solar system experiments. We have solved the Friedman equations for the full dynamical range of the evolution of the Universe. This allows us to perform a detailed analysis of Supernovae data in the context of such models that results in an excellent fit. Hence, inverse curvature gravity models represent an example of phenomenologically viable models in which the current acceleration of the Universe is driven by curvature instead of dark energy. If we further include constraints on the current expansion rate of the Universe from the Hubble Space Telescope and on the age of the Universe from globular clusters, we obtain that the matter content of the Universe is 0.07 {le} {omega}{sub m} {le} 0.21 (95% Confidence). Hence the inverse curvature gravity models considered can not explain the dynamics of the Universe just with a baryonic matter component.
Photon Drag Effect due to Berry Curvature.
Kurosawa, Hiroyuki; Sawada, Kei; Ohno, Seigo
2016-08-19
A theoretical investigation reveals that the photon drag effect (PDE) is induced in a grating slab with deformation by the Berry curvature in phase space. It drifts the momentum of light, and gives asymmetric PDE signals in momentum space. Large PDE signals are observed even near the Γ point. This characteristic agrees well with our theoretical results. PMID:27588858
Membrane Curvature Sensing by Amphipathic Helices
Jensen, Martin Borch; Bhatia, Vikram Kjøller; Jao, Christine C.; Rasmussen, Jakob Ewald; Pedersen, Søren L.; Jensen, Knud J.; Langen, Ralf; Stamou, Dimitrios
2011-01-01
Preferential binding of proteins on curved membranes (membrane curvature sensing) is increasingly emerging as a general mechanism whereby cells may effect protein localization and trafficking. Here we use a novel single liposome fluorescence microscopy assay to examine a common sensing motif, the amphipathic helix (AH), and provide quantitative measures describing and distinguishing membrane binding and sensing behavior. By studying two AH-containing proteins, α-synuclein and annexin B12, as well as a range of AH peptide mutants, we reveal that both the hydrophobic and hydrophilic faces of the helix greatly influence binding and sensing. Although increased hydrophobic and electrostatic interactions with the membrane both lead to greater densities of bound protein, the former yields membrane curvature-sensitive binding, whereas the latter is not curvature-dependent. However, the relative contributions of both components determine the sensing of AHs. In contrast, charge density in the lipid membrane seems important primarily in attracting AHs to the membrane but does not significantly influence sensing. These observations were made possible by the ability of our assay to distinguish within our samples liposomes with and without bound protein as well as the density of bound protein. Our findings suggest that the description of membrane curvature-sensing requires consideration of several factors such as short and long range electrostatic interactions, hydrogen bonding, and the volume and structure of inserted hydrophobic residues. PMID:21953452
Graph Curvature for Differentiating Cancer Networks
Sandhu, Romeil; Georgiou, Tryphon; Reznik, Ed; Zhu, Liangjia; Kolesov, Ivan; Senbabaoglu, Yasin; Tannenbaum, Allen
2015-01-01
Cellular interactions can be modeled as complex dynamical systems represented by weighted graphs. The functionality of such networks, including measures of robustness, reliability, performance, and efficiency, are intrinsically tied to the topology and geometry of the underlying graph. Utilizing recently proposed geometric notions of curvature on weighted graphs, we investigate the features of gene co-expression networks derived from large-scale genomic studies of cancer. We find that the curvature of these networks reliably distinguishes between cancer and normal samples, with cancer networks exhibiting higher curvature than their normal counterparts. We establish a quantitative relationship between our findings and prior investigations of network entropy. Furthermore, we demonstrate how our approach yields additional, non-trivial pair-wise (i.e. gene-gene) interactions which may be disrupted in cancer samples. The mathematical formulation of our approach yields an exact solution to calculating pair-wise changes in curvature which was computationally infeasible using prior methods. As such, our findings lay the foundation for an analytical approach to studying complex biological networks. PMID:26169480
Graph Curvature for Differentiating Cancer Networks
NASA Astrophysics Data System (ADS)
Sandhu, Romeil; Georgiou, Tryphon; Reznik, Ed; Zhu, Liangjia; Kolesov, Ivan; Senbabaoglu, Yasin; Tannenbaum, Allen
2015-07-01
Cellular interactions can be modeled as complex dynamical systems represented by weighted graphs. The functionality of such networks, including measures of robustness, reliability, performance, and efficiency, are intrinsically tied to the topology and geometry of the underlying graph. Utilizing recently proposed geometric notions of curvature on weighted graphs, we investigate the features of gene co-expression networks derived from large-scale genomic studies of cancer. We find that the curvature of these networks reliably distinguishes between cancer and normal samples, with cancer networks exhibiting higher curvature than their normal counterparts. We establish a quantitative relationship between our findings and prior investigations of network entropy. Furthermore, we demonstrate how our approach yields additional, non-trivial pair-wise (i.e. gene-gene) interactions which may be disrupted in cancer samples. The mathematical formulation of our approach yields an exact solution to calculating pair-wise changes in curvature which was computationally infeasible using prior methods. As such, our findings lay the foundation for an analytical approach to studying complex biological networks.
Evaluation of a High-Resolution Regional Climate Ensemble
NASA Astrophysics Data System (ADS)
Bruyere, C. L.; Tye, M. R.; Keellings, D.; Jaye, A.
2014-12-01
A high-resolution Regional Climate Ensemble is used to investigate the limits of predictability of climate simulations, with a focus on high-impact weather. A diverse set of approaches are being applied to examine the impact of the different physics parameterizations on the simulated climate and high-impact weather statistics and to determine the physics combinations that result in realistic scenarios. In this paper we focus on the ensemble members' ability to correctly simulate current climate variability in terms of: 1) extreme temperature and precipitation over different regions, and 2) tropical cyclone statistics. A twenty-four member physics ensemble of climate simulations has been generated using the state-of-the-art Weather Research and Forecasting Model (Skamarock et al. 2008). The ensemble model has been run over an extended North American domain of approximately 25° S to 70° N and from the African coast to the East Pacific, and at sufficient resolution to capture high-impact weather events. Skamarock, W., J. B. Klemp, J. Dudhia, D. O. Gill, D. Barker, M. G. Duda, X. Huang, and W. Wang, 2008: A Description of the Advanced Research WRF Version 3. NCAR Technical Note NCAR/TN-475+STR. Boulder, CO.
Myopic aberrations: Simulation based comparison of curvature and Hartmann Shack wavefront sensors
NASA Astrophysics Data System (ADS)
Basavaraju, Roopashree M.; Akondi, Vyas; Weddell, Stephen J.; Budihal, Raghavendra Prasad
2014-02-01
In comparison with a Hartmann Shack wavefront sensor, the curvature wavefront sensor is known for its higher sensitivity and greater dynamic range. The aim of this study is to numerically investigate the merits of using a curvature wavefront sensor, in comparison with a Hartmann Shack (HS) wavefront sensor, to analyze aberrations of the myopic eye. Aberrations were statistically generated using Zernike coefficient data of 41 myopic subjects obtained from the literature. The curvature sensor is relatively simple to implement, and the processing of extra- and intra-focal images was linearly resolved using the Radon transform to provide Zernike modes corresponding to statistically generated aberrations. Simulations of the HS wavefront sensor involve the evaluation of the focal spot pattern from simulated aberrations. Optical wavefronts were reconstructed using the slope geometry of Southwell. Monte Carlo simulation was used to find critical parameters for accurate wavefront sensing and to investigate the performance of HS and curvature sensors. The performance of the HS sensor is highly dependent on the number of subapertures and the curvature sensor is largely dependent on the number of Zernike modes used to represent the aberration and the effective propagation distance. It is shown that in order to achieve high wavefront sensing accuracy while measuring aberrations of the myopic eye, a simpler and cost effective curvature wavefront sensor is a reliable alternative to a high resolution HS wavefront sensor with a large number of subapertures.
Calculation of free energies in fluid membranes subject to heterogeneous curvature fields
NASA Astrophysics Data System (ADS)
Agrawal, Neeraj J.; Radhakrishnan, Ravi
2009-07-01
We present a computational methodology for incorporating thermal effects and calculating relative free energies for elastic fluid membranes subject to spatially dependent intrinsic curvature fields using the method of thermodynamic integration. Based on a simple model for the intrinsic curvature imposed only in a localized region of the membrane, we employ thermodynamic integration to calculate the free-energy change as a function of increasing strength of the intrinsic curvature field and a thermodynamic cycle to compute free-energy changes for different sizes of the localized region. By explicitly computing the free-energy changes and by quantifying the loss of entropy accompanied with increasing membrane deformation, we show that the membrane stiffness increases with increasing intrinsic field, thereby, renormalizing the membrane bending rigidity. The second main conclusion of this work is that the entropy of the membrane decreases with increasing size of the localized region subject to the curvature field. Our results help to quantify the free-energy change when a planar membrane deforms under the influence of curvature-inducing proteins at a finite temperature.
Regional High-resolution Coupled Atmosphere Ocean Modelling in the North Sea Region
NASA Astrophysics Data System (ADS)
Dumenil-Gates, Lydia; Bülow, Katharina; Ganske, Anette; Heinrich, Hartmut; Klein, Birgit; Klein, Holger; Möller, Jens; Rosenhagen, Gudrun; Schade, Nils; Hüttl-Kabus, Sabine; Tinz, Birger
2015-04-01
The analysis of climate projections in the North Sea area is one of the research tasks of the research programme KLIWAS of the German Federal Ministry of Transport and Digital Infrastructure. A multi-model ensemble of three coupled regional atmosphere-ocean models was set up comprising very high resolution simulations for the German coastal regions of the North Sea and the Baltic to represent the complex land-sea-atmosphere conditions in the region. The ensemble consists of simulations made in cooperation with the Swedish Meteorological and Hydrological Institute, the Climate Service Centre and the Max-Planck-Institute for the period of 1950 to 2100. The KLIWAS project thereby adds coupled models to the band-width of possible future climate conditions in the atmosphere as given by the ENSEMBLES project, which were also analyzed. The coupled results are evaluated for present-day climate using a North Sea climatology of maritime conditions at a matching high resolution. In the future climate, while air and water temperatures will rise to the year 2100, the mean wind speed does not show a significant trend, but large decadal variability. The frequency of occurrence of westerly wind directions increases in the majority of simulations and results in an increase of significant wave height in the eastern parts of the North Sea. In an interdisciplinary approach, these results are used to provide regional to local information for the development of adaptation strategies for the estuary, and climate-proofing of infrastructure in the wider context of the project.
A high-resolution regional reanalysis for the European CORDEX region
NASA Astrophysics Data System (ADS)
Bollmeyer, Christoph; Keller, Jan; Ohlwein, Christian; Wahl, Sabrina
2015-04-01
Within the Hans-Ertel-Centre for Weather Research (HErZ), the climate monitoring branch concentrates efforts on the assessment and analysis of regional climate in Germany and Europe. In joint cooperation with DWD (German Weather Service), a high-resolution reanalysis system based on the COSMO model has been developed. Reanalyses gain more and more importance as a source of meteorological information for many purposes and applications. Several global reanalyses projects (e.g., ERA, MERRA, CSFR, JMA9) produce and verify these data sets to provide time series as long as possible combined with a high data quality. Due to a spatial resolution down to 50-70km and 3-hourly temporal output, they are not suitable for small scale problems (e.g., regional climate assessment, meso-scale NWP verification, input for subsequent models such as river runoff simulations, renewable energy applications). The implementation of regional reanalyses based on a limited area model along with a data assimilation scheme is able to generate reanalysis data sets with high spatio-temporal resolution. The work presented here focuses on two regional reanalyses for Europe and Germany. The European reanalysis COSMO-REA6 matches the CORDEX EURO-11 specifications, albeit at a higher spatial resolution, i.e., 0.055° (6km) instead of 0.11° (12km). Nested into COSMO-REA6 is COSMO-REA2, a convective-scale reanalysis with 2km resolution for Germany. COSMO-REA6 comprises the assimilation of observational data using the existing nudging scheme of COSMO and is complemented by a special soil moisture analysis and boundary conditions given by ERA-Interim data. COSMO-REA2 also uses the nudging scheme complemented by a latent heat nudging of radar information. The reanalysis data set currently covers 17 years (1997-2013) for COSMO-REA6 and 4 years (2010-2013) for COSMO-REA2 with a very large set of output variables and a high temporal output step of hourly 3D-fields and quarter-hourly 2D-fields. The evaluation
Stagnation Region Heat Transfer Augmentation at Very High Turbulence Levels
Ames, Forrest; Kingery, Joseph E.
2015-06-17
A database for stagnation region heat transfer has been extended to include heat transfer measurements acquired downstream from a new high intensity turbulence generator. This work was motivated by gas turbine industry heat transfer designers who deal with heat transfer environments with increasing Reynolds numbers and very high turbulence levels. The new mock aero-combustor turbulence generator produces turbulence levels which average 17.4%, which is 37% higher than the older turbulence generator. The increased level of turbulence is caused by the reduced contraction ratio from the liner to the exit. Heat transfer measurements were acquired on two large cylindrical leading edge test surfaces having a four to one range in leading edge diameter (40.64 cm and 10.16 cm). Gandvarapu and Ames [1] previously acquired heat transfer measurements for six turbulence conditions including three grid conditions, two lower turbulence aero-combustor conditions, and a low turbulence condition. The data are documented and tabulated for an eight to one range in Reynolds numbers for each test surface with Reynolds numbers ranging from 62,500 to 500,000 for the large leading edge and 15,625 to 125,000 for the smaller leading edge. The data show augmentation levels of up to 136% in the stagnation region for the large leading edge. This heat transfer rate is an increase over the previous aero-combustor turbulence generator which had augmentation levels up to 110%. Note, the rate of increase in heat transfer augmentation decreases for the large cylindrical leading edge inferring only a limited level of turbulence intensification in the stagnation region. The smaller cylindrical leading edge shows more consistency with earlier stagnation region heat transfer results correlated on the TRL (Turbulence, Reynolds number, Length scale) parameter. The downstream regions of both test surfaces continue to accelerate the flow but at a much lower rate than the leading edge. Bypass transition occurs
High power VCSEL device with periodic gain active region
NASA Astrophysics Data System (ADS)
Ning, Y. Q., II; Qin, L.; Sun, Y. F.; Li, T.; Cui, J. J.; Peng, B.; Liu, G. Y.; Zhang, Y.; Liu, Y.; Wang, L. J.; Cui, D. F.; Xu, Z. Y.
2007-11-01
High power vertical cavity surface emitting lasers with large aperture have been fabricated through improving passivation, lateral oxidation and heat dissipation techniques. Different from conventional three quantum well structure, a periodic gain active region with nine quantum wells was incorporated into the VCSEL structure, with which high efficiency and high power operation were expected. The nine quantum wells were divided into three groups with each of them located at the antinodes of the cavity to enhance the coupling between the optical field and the gain region. Large aperture and bottom-emitting configuration was used to improve the beam quality and the heat dissipation. A maximum output power of 1.4W was demonstrated at CW operation for a 400μm-diameter device. The lasing wavelength shifted to 995.5nm with a FWHM of 2nm at a current of 4.8A due to the internal heating and the absence of active water cooling. A ring-shape farfield pattern was induced by the non-homogeneous lateral current distribution in large diameter device. The light intensity at the center of the ring increased with increasing current. A symmetric round light spot at the center and single transverse mode operation with a divergence angle of 16° were observed with current beyond 4.8A.
Mean cortical curvature reflects cytoarchitecture restructuring in mild traumatic brain injury.
King, Jace B; Lopez-Larson, Melissa P; Yurgelun-Todd, Deborah A
2016-01-01
In the United States alone, the number of persons living with the enduring consequences of traumatic brain injuries is estimated to be between 3.2 and 5 million. This number does not include individuals serving in the United States military or seeking care at Veterans Affairs hospitals. The importance of understanding the neurobiological consequences of mild traumatic brain injury (mTBI) has increased with the return of veterans from conflicts overseas, many of who have suffered this type of brain injury. However, identifying the neuroanatomical regions most affected by mTBI continues to prove challenging. The aim of this study was to assess the use of mean cortical curvature as a potential indicator of progressive tissue loss in a cross-sectional sample of 54 veterans with mTBI compared to 31 controls evaluated with MRI. It was hypothesized that mean cortical curvature would be increased in veterans with mTBI, relative to controls, due in part to cortical restructuring related to tissue volume loss. Mean cortical curvature was assessed in 60 bilateral regions (31 sulcal, 29 gyral). Of the 120 regions investigated, nearly 50% demonstrated significantly increased mean cortical curvature in mTBI relative to controls with 25% remaining significant following multiple comparison correction (all, pFDR < .05). These differences were most prominent in deep gray matter regions of the cortex. Additionally, significant relationships were found between mean cortical curvature and gray and white matter volumes (all, p < .05). These findings suggest potentially unique patterns of atrophy by region and indicate that changes in brain microstructure due to mTBI are sensitive to measures of mean curvature. PMID:26909332
Mean cortical curvature reflects cytoarchitecture restructuring in mild traumatic brain injury
King, Jace B.; Lopez-Larson, Melissa P.; Yurgelun-Todd, Deborah A.
2016-01-01
In the United States alone, the number of persons living with the enduring consequences of traumatic brain injuries is estimated to be between 3.2 and 5 million. This number does not include individuals serving in the United States military or seeking care at Veterans Affairs hospitals. The importance of understanding the neurobiological consequences of mild traumatic brain injury (mTBI) has increased with the return of veterans from conflicts overseas, many of who have suffered this type of brain injury. However, identifying the neuroanatomical regions most affected by mTBI continues to prove challenging. The aim of this study was to assess the use of mean cortical curvature as a potential indicator of progressive tissue loss in a cross-sectional sample of 54 veterans with mTBI compared to 31 controls evaluated with MRI. It was hypothesized that mean cortical curvature would be increased in veterans with mTBI, relative to controls, due in part to cortical restructuring related to tissue volume loss. Mean cortical curvature was assessed in 60 bilateral regions (31 sulcal, 29 gyral). Of the 120 regions investigated, nearly 50% demonstrated significantly increased mean cortical curvature in mTBI relative to controls with 25% remaining significant following multiple comparison correction (all, pFDR < .05). These differences were most prominent in deep gray matter regions of the cortex. Additionally, significant relationships were found between mean cortical curvature and gray and white matter volumes (all, p < .05). These findings suggest potentially unique patterns of atrophy by region and indicate that changes in brain microstructure due to mTBI are sensitive to measures of mean curvature. PMID:26909332
Highly ionized region surrounding SN Refsdal revealed by MUSE
NASA Astrophysics Data System (ADS)
Karman, W.; Grillo, C.; Balestra, I.; Rosati, P.; Caputi, K. I.; Di Teodoro, E.; Fraternali, F.; Gavazzi, R.; Mercurio, A.; Prochaska, J. X.; Rodney, S.; Treu, T.
2016-01-01
Supernova (SN) Refsdal is the first multiply imaged, highly magnified, and spatially resolved SN ever observed. The SN exploded in a highly magnified spiral galaxy at z = 1.49 behind the Frontier Fields cluster MACS1149, and provides a unique opportunity to study the environment of SNe at high z. We exploit the time delay between multiple images to determine the properties of the SN and its environment before, during, and after the SN exploded. We use the integral-field spectrograph MUSE on the VLT to simultaneously target all observed and model-predicted positions of SN Refsdal. We find Mg II emission at all positions of SN Refsdal, accompanied by weak Fe II* emission at two positions. The measured ratios of [O II] to Mg II emission of 10-20 indicate a high degree of ionization with low metallicity. Because the same high degree of ionization is found in all images, and our spatial resolution is too coarse to resolve the region of influence of SN Refsdal, we conclude that this high degree of ionization has been produced by previous SNe or a young and hot stellar population. We find no variability of the [O II] line over a period of 57 days. This suggests that there is no variation in the [O II] luminosity of the SN over this period, or that the SN has a small contribution to the integrated [O II] emission over the scale resolved by our observations.
How to calculate normal curvatures of sampled geological surfaces
NASA Astrophysics Data System (ADS)
Bergbauer, Stephan; Pollard, David D.
2003-02-01
Curvature has been used both to describe geological surfaces and to predict the distribution of deformation in folded or domed strata. Several methods have been proposed in the geoscience literature to approximate the curvature of surfaces; however we advocate a technique for the exact calculation of normal curvature for single-valued gridded surfaces. This technique, based on the First and Second Fundamental Forms of differential geometry, allows for the analytical calculation of the magnitudes and directions of principal curvatures, as well as Gaussian and mean curvature. This approach is an improvement over previous methods to calculate surface curvatures because it avoids common mathematical approximations, which introduce significant errors when calculated over sloped horizons. Moreover, the technique is easily implemented numerically as it calculates curvatures directly from gridded surface data (e.g. seismic or GPS data) without prior surface triangulation. In geological curvature analyses, problems arise because of the sampled nature of geological horizons, which introduces a dependence of calculated curvatures on the sample grid. This dependence makes curvature analysis without prior data manipulation problematic. To ensure a meaningful curvature analysis, surface data should be filtered to extract only those surface wavelengths that scale with the feature under investigation. A curvature analysis of the top-Pennsylvanian horizon at Goose Egg dome, Wyoming shows that sampled surfaces can be smoothed using a moving average low-pass filter to extract curvature information associated with the true morphology of the structure.
Stress compensation for arbitrary curvature control in vanadium dioxide phase transition actuators
NASA Astrophysics Data System (ADS)
Dong, Kaichen; Lou, Shuai; Choe, Hwan Sung; Liu, Kai; You, Zheng; Yao, Jie; Wu, Junqiao
2016-07-01
Due to its thermally driven structural phase transition, vanadium dioxide (VO2) has emerged as a promising material for micro/nano-actuators with superior volumetric work density, actuation amplitude, and repetition frequency. However, the high initial curvature of VO2 actuators severely obstructs the actuation performance and application. Here, we introduce a "seesaw" method of fabricating tri-layer cantilevers to compensate for the residual stress and realize nearly arbitrary curvature control of VO2 actuators. By simply adjusting the thicknesses of the individual layers, cantilevers with positive, zero, or negative curvatures can be engineered. The actuation amplitude can be decoupled from the curvature and controlled independently as well. Based on the experimentally measured residual stresses, we demonstrate sub-micron thick VO2 actuators with nearly zero final curvature and a high actuation amplitude simultaneously. This "seesaw" method can be further extended to the curvature engineering of other microelectromechanical system multi-layer structures where large stress-mismatch between layers are inevitable.
No large scale curvature perturbations during the waterfall phase transition of hybrid inflation
Abolhasani, Ali Akbar; Firouzjahi, Hassan
2011-03-15
In this paper the possibility of generating large scale curvature perturbations induced from the entropic perturbations during the waterfall phase transition of the standard hybrid inflation model is studied. We show that whether or not appreciable amounts of large scale curvature perturbations are produced during the waterfall phase transition depends crucially on the competition between the classical and the quantum mechanical backreactions to terminate inflation. If one considers only the classical evolution of the system, we show that the highly blue-tilted entropy perturbations induce highly blue-tilted large scale curvature perturbations during the waterfall phase transition which dominate over the original adiabatic curvature perturbations. However, we show that the quantum backreactions of the waterfall field inhomogeneities produced during the phase transition dominate completely over the classical backreactions. The cumulative quantum backreactions of very small scale tachyonic modes terminate inflation very efficiently and shut off the curvature perturbation evolution during the waterfall phase transition. This indicates that the standard hybrid inflation model is safe under large scale curvature perturbations during the waterfall phase transition.
On the Frozen Soil Scheme for High Latitude Regions
NASA Astrophysics Data System (ADS)
Ganji, A.; Sushama, L.
2014-12-01
Regional and global climate model simulated streamflows for high-latitude regions show systematic biases, particularly in the timing and magnitude of spring peak flows. Though these biases could be related to the snow water equivalent and spring temperature biases in models, a good part of these biases is due to the unaccounted effects of non-uniform infiltration capacity of the frozen ground and other related processes. In this paper, the frozen scheme in the Canadian Land Surface Scheme (CLASS), which is used in the Canadian regional and global climate models, is modified to include fractional permeable area, supercooled liquid water and a new formulation for hydraulic conductivity. Interflow is also included in these experiments presented in this study to better explain the steamflows after snow melt season. The impact of these modifications on the regional hydrology, particularly streamflow, is assessed by comparing three simulations, performed with the original and two modified versions of CLASS, driven by atmospheric forcing data from the European Centre for Medium-Range Weather Forecasts (ECMWF) reanalysis data (ERA-Interim), for the 1990-2001 period, over a northeast Canadian domain. The two modified versions of CLASS differ in the soil hydraulic conductivity and matric potential formulations, with one version being based on formulations from a previous study and the other one is newly proposed. Results suggest statistically significant decreases in infiltration for the simulation with the new hydraulic conductivity and matric potential formulations and fractional permeable area concept, compared to the original version of CLASS, which is also reflected in the increased spring surface runoff and streamflows in this simulation with modified CLASS, over most of the study domain. The simulated spring peaks and their timing in this simulation is also in better agreement to those observed.
Effects of corotating interaction regions on ULYSSES high energy particles
Droege, W.; Kunow, H.; Raviart, A.
1995-09-01
Since June 1992 the Kiel Electron Telescope on board ULYSSES measures variations of more than 10% in the fluxes of high energy H and He showing a periodicity of about 26 days in coincidence with the passage of corotating interaction regions. (CIR). At low energies MeV protons are accelerated at the shocks of the CIRs. These effects are observed up to high southern latitudes, where the signature of a CIR is no longer visible in plasma or magnetic field data. After passing over the south polar cap ULYSSES has now returned to the solar equator and climbs up to the north pole. In this paper we study the relative intensity variations with latitude and the latitude dependence at solar distances smaller than ever studied before.
Modelization of highly nonlinear waves in coastal regions
NASA Astrophysics Data System (ADS)
Gouin, Maïté; Ducrozet, Guillaume; Ferrant, Pierre
2015-04-01
The proposed work deals with the development of a highly non-linear model for water wave propagation in coastal regions. The accurate modelization of surface gravity waves is of major interest in ocean engineering, especially in the field of marine renewable energy. These marine structures are intended to be settled in coastal regions where the effect of variable bathymetry may be significant on local wave conditions. This study presents a numerical model for the wave propagation with complex bathymetry. It is based on High-Order Spectral (HOS) method, initially limited to the propagation of non-linear wave fields over flat bottom. Such a model has been developed and validated at the LHEEA Lab. (Ecole Centrale Nantes) over the past few years and the current developments will enlarge its application range. This new numerical model will keep the interesting numerical properties of the original pseudo-spectral approach (convergence, efficiency with the use of FFTs, …) and enable the possibility to propagate highly non-linear wave fields over long time and large distance. Different validations will be provided in addition to the presentation of the method. At first, Bragg reflection will be studied with the proposed approach. If the Bragg condition is satisfied, the reflected wave generated by a sinusoidal bottom patch should be amplified as a result of resonant quadratic interactions between incident wave and bottom. Comparisons will be provided with experiments and reference solutions. Then, the method will be used to consider the transformation of a non-linear monochromatic wave as it propagates up and over a submerged bar. As the waves travel up the front slope of the bar, it steepens and high harmonics are generated due to non-linear interactions. Comparisons with experimental data will be provided. The different test cases will assess the accuracy and efficiency of the method proposed.
High beta and second stability region transport and stability analysis
Hughes, M.H.; Phillps, M.W.; Todd, A.M.M.; Krishnaswami, J.; Hartley, R.
1992-09-01
This report describes ideal and resistive studies of high-beta plasmas and of the second stability region. Emphasis is focused on supershot'' plasmas in TFIR where MHD instabilities are frequently observed and which spoil their confinement properties. Substantial results are described from the analysis of these high beta poloidal plasmas. During these studies, initial pressure and safety factor profiles were obtained from the TRANSP code, which is used extensively to analyze experimental data. Resistive MBD stability studies of supershot equilibria show that finite pressure stabilization of tearing modes is very strong in these high {beta}p plasmas. This has prompted a detailed re-examination of linear tearing mode theory in which we participated in collaboration with Columbia University and General Atomics. This finite pressure effect is shown to be highly sensitive to small scale details of the pressure profile. Even when an ad hoc method of removing this stabilizing mechanism is implemented, however, it is shown that there is only superficial agreement between resistive MBD stability computation and the experimental data. While the mode structures observed experimentally can be found computationally, there is no convincing correlation with the experimental observations when the computed results are compared with a large set of supershot data. We also describe both the ideal and resistive stability properties of TFIR equilibria near the transition to the second region. It is shown that the highest {beta} plasmas, although stable to infinite-n ideal ballooning modes, can be unstable to the so called infernal'' modes associated with small shear. The sensitivity of these results to the assumed pressure and current density profiles is discussed. Finally, we describe results from two collaborative studies with PPPL. The first involves exploratory studies of the role of the 1/1 mode in tokamaks and, secondly, a study of sawtooth stabilization using ICRF.
NASA Astrophysics Data System (ADS)
Chitta, Varun
Modeling of complex flows involving the combined effects of flow transition and streamline curvature using two advanced turbulence models, one in the Reynolds-averaged Navier-Stokes (RANS) category and the other in the hybrid RANS-Large eddy simulation (LES) category is considered in this research effort. In the first part of the research, a new scalar eddy-viscosity model (EVM) is proposed, designed to exhibit physically correct responses to flow transition, streamline curvature, and system rotation effects. The four equation model developed herein is a curvature-sensitized version of a commercially available three-equation transition-sensitive model. The physical effects of rotation and curvature (RC) enter the model through the added transport equation, analogous to a transverse turbulent velocity scale. The eddy-viscosity has been redefined such that the proposed model is constrained to reduce to the original transition-sensitive model definition in nonrotating flows or in regions with negligible RC effects. In the second part of the research, the developed four-equation model is combined with a LES technique using a new hybrid modeling framework, dynamic hybrid RANS-LES. The new framework is highly generalized, allowing coupling of any desired LES model with any given RANS model and addresses several deficiencies inherent in most current hybrid models. In the present research effort, the DHRL model comprises of the proposed four-equation model for RANS component and the MILES scheme for LES component. Both the models were implemented into a commercial computational fluid dynamics (CFD) solver and tested on a number of engineering and generic flow problems. Results from both the RANS and hybrid models show successful resolution of the combined effects of transition and curvature with reasonable engineering accuracy, and for only a small increase in computational cost. In addition, results from the hybrid model indicate significant levels of turbulent
High Resolution Regional Climate Modeling for Lebanon, Eastern Mediterranean Coast
NASA Astrophysics Data System (ADS)
Katurji, Marwan; Soltanzadeh, Iman; Kuhnlein, Meike; Zawar-Reza, Peyman
2013-04-01
The Eastern Mediterranean coast consists of Lebanon, Palestine, Syria, Israel and a small part of southern Turkey. The region lies between latitudes 30 degrees S and 40 degrees N, which makes its climate affected by westerly propagating wintertime cyclones spinning off mid-latitude troughs (December, January and February), while during summer (June, July and August) the area is strongly affected by the sub-tropical anti-cyclonic belt as a result of the descending air of the Hadley cell circulation system. The area is considered to be in a transitional zone between tropical to mid-latitude climate regimes, and having a coastal topography up to 3000 m in elevation (like in the Western Ranges of Lebanon), which emphasizes the complexity of climate variability in this area under future predictions of climate change. This research incorporates both regional climate numerical simulations, Tropical Rainfall Measuring Mission (TRMM) satellite derived and surface rain gauge rainfall data to evaluate the Regional Climate Model (RegCM) version 4 ability to represent both the mean and variance of observed precipitation in the Eastern Mediterranean Region, with emphasis on the Lebanese coastal terrain and mountain ranges. The adopted methodology involves dynamically down scaling climate data from reanalysis synoptic files through a double nesting procedure. The retrospective analysis of 13 years with both 50 and 10 km spatial resolution allows for the assessment of the model results on both a climate scale and specific high intensity precipitating events. The spatial averaged mean bias error in precipitation rate for the rainy season predicted by RegCM 50 and 10 km resolution grids was 0.13 and 0.004 mm hr-1 respectively. When correlating RegCM and TRMM precipitation rate for the domain covering Lebanon's coastal mountains, the root mean square error (RMSE) for the mean quantities over the 13-year period was only 0.03, while the RMSE for the standard deviation was higher by one
Curvature Dependence of Hydrophobic Hydration Dynamics
NASA Astrophysics Data System (ADS)
Weiß, R. Gregor; Heyden, Matthias; Dzubiella, Joachim
2015-05-01
We investigate the solute curvature dependence of water dynamics in the vicinity of hydrophobic spherical solutes using molecular dynamics simulations. For both the lateral and perpendicular diffusivity, as well as for H-bond kinetics of water in the first hydration shell, we find a nonmonotonic solute-size dependence, exhibiting extrema close to the well-known structural crossover length scale for hydrophobic hydration. Additionally, we find an apparent anomalous diffusion for water moving parallel to the surface of small solutes, which, however, can be explained by topology effects. Our findings regarding the intimate connection between solute curvature and water dynamics has implications for our understanding of hydration dynamics at heterogeneous biomolecular surfaces.
Cosmological signatures of anisotropic spatial curvature
NASA Astrophysics Data System (ADS)
Pereira, Thiago S.; Mena Marugán, Guillermo A.; Carneiro, Saulo
2015-07-01
If one is willing to give up the cherished hypothesis of spatial isotropy, many interesting cosmological models can be developed beyond the simple anisotropically expanding scenarios. One interesting possibility is presented by shear-free models in which the anisotropy emerges at the level of the curvature of the homogeneous spatial sections, whereas the expansion is dictated by a single scale factor. We show that such models represent viable alternatives to describe the large-scale structure of the inflationary universe, leading to a kinematically equivalent Sachs-Wolfe effect. Through the definition of a complete set of spatial eigenfunctions we compute the two-point correlation function of scalar perturbations in these models. In addition, we show how such scenarios would modify the spectrum of the CMB assuming that the observations take place in a small patch of a universe with anisotropic curvature.
Coarse-grained modeling of DNA curvature
NASA Astrophysics Data System (ADS)
Freeman, Gordon S.; Hinckley, Daniel M.; Lequieu, Joshua P.; Whitmer, Jonathan K.; de Pablo, Juan J.
2014-10-01
The interaction of DNA with proteins occurs over a wide range of length scales, and depends critically on its local structure. In particular, recent experimental work suggests that the intrinsic curvature of DNA plays a significant role on its protein-binding properties. In this work, we present a coarse grained model of DNA that is capable of describing base-pairing, hybridization, major and minor groove widths, and local curvature. The model represents an extension of the recently proposed 3SPN.2 description of DNA [D. M. Hinckley, G. S. Freeman, J. K. Whitmer, and J. J. de Pablo, J. Chem. Phys. 139, 144903 (2013)], into which sequence-dependent shape and mechanical properties are incorporated. The proposed model is validated against experimental data including melting temperatures, local flexibilities, dsDNA persistence lengths, and minor groove width profiles.
Tube curvature measuring probe and method
Sokol, George J.
1990-01-01
The present invention is directed to a probe and method for measuring the radius of curvature of a bend in a section of tubing. The probe includes a member with a pair of guide means, one located at each end of the member. A strain gauge is operatively connected to the member for detecting bending stress exrted on the member as the probe is drawn through and in engagement with the inner surface of a section of tubing having a bend. The method of the present invention includes steps utilizing a probe, like the aforementioned probe, which can be made to detect bends only in a single plane when having a fixed orientation relative the section of tubing to determine the maximum radius of curvature of the bend.
[Analysis and Correction of Spectral Curvature in Hadamard Transform Spectrometer with DMD].
Quan, Xiang-qian; Liu, Hua; Lu, Zhen-wu; Wang, Xiao-duo; Dang, Bo-shi; Chen, Xiang-zi; Wang, Fang
2016-02-01
Due to the advantages of its low cost and high utilization rate of light energy and no moving parts, Hadamard transform spectrometer with DMD has become a focus in the research of spectrometer. In order to solve the reduction of spectral resolution caused by the spectral curvature of Hadamard transform spectrometer with DMD (Digital Micro-mirror Device), the spectral aliasing in the spectrometer was investigated. Firstly, the mathematical relationship of spectral aliasing to radius of spectral curvature was deduced. Then, two procedures were proposed to solve the spectral aliasing. One is making the DMD encoded spectral band accordant with the standard spectral band as far as possible by adjusting the DMD-encoded stripe, and another is correcting remaining spectral aliasing by means of data processing. Finally, by analyzing and correcting spectral curvature in six situations of the curvature radius of 15.8 x 10⁴, 7.8 x 10⁴, 9.7 x 10⁴ µm and etc, we fit out the relationship of spectral aliasing and spectrum correction effect of spectral-curvature to the curvature radius. The simulation indicates that the spectral resolution increases to the resolution of optical system. It shows that the proposed methods are universal, simple and effective in the improvement of spectral resolution. PMID:27209768
NASA Astrophysics Data System (ADS)
Šprlák, Michal; Novák, Pavel; Pitoňák, Martin
2016-05-01
In this study we assume that a gravitational curvature tensor, i.e. a tensor of third-order directional derivatives of the Earth's gravitational potential, is observable at satellite altitudes. Such a tensor is composed of ten different components, i.e. gravitational curvatures, which may be combined into vertical-vertical-vertical, vertical-vertical-horizontal, vertical-horizontal-horizontal and horizontal-horizontal-horizontal gravitational curvatures. Firstly, we study spectral properties of the gravitational curvatures. Secondly, we derive new quadrature formulas for the spherical harmonic analysis of the four gravitational curvatures and provide their corresponding analytical error models. Thirdly, requirements for an instrument that would eventually observe gravitational curvatures by differential accelerometry are investigated. The results reveal that measuring third-order directional derivatives of the gravitational potential imposes very high requirements on the accuracy of deployed accelerometers which are beyond the limits of currently available sensors. For example, for orbital parameters and performance similar to those of the GOCE mission, observing third-order directional derivatives requires accelerometers with the noise level of {˜}10^{-17} {m} {s}^{-2} Hz^{-1/2}.
Curvature sensing MARCKS-ED peptides bind to membranes in a stereo-independent manner.
Yan, Lei; de Jesus, Armando Jerome; Tamura, Ryo; Li, Victoria; Cheng, Kui; Yin, Hang
2015-07-01
Membrane curvature and lipid composition plays a critical role in interchanging of matter and energy in cells. Peptide curvature sensors are known to activate signaling pathways and promote molecular transport across cell membranes. Recently, the 25-mer MARCKS-ED peptide, which is derived from the effector domain of the myristoylated alanine-rich C kinase substrate protein, has been reported to selectively recognize highly curved membrane surfaces. Our previous studies indicated that the naturally occurring L-MARCKS-ED peptide could simultaneously detect both phosphatidylserine and curvature. Here, we demonstrate that D-MARCKS-ED, composed by unnatural D-amino acids, has the same activities as its enantiomer, L-MARCKS-ED, as a curvature and lipid sensor. An atomistic molecular dynamics simulation suggests that D-MARCKS-ED may change from linear to a boat conformation upon binding to the membrane. Comparable enhancement of fluorescence intensity was observed between D- and L-MARCKS-ED peptides, indicating similar binding affinities. Meanwhile, circular dichroism spectra of D- and L-MARCKS-ED are almost symmetrical both in the presence and absence of liposomes. These results suggest similar behavior of artificial D- and natural L-MARCKS-ED peptides when binding to curved membranes. Our studies may contribute to further understanding of how MARCKS-ED senses membrane curvature as well as provide a new direction to develop novel membrane curvature probes. PMID:25851418
Transformation optics, curvature and beyond (Conference Presentation)
NASA Astrophysics Data System (ADS)
McCall, Martin W.
2016-04-01
Although the transformation algorithm is very well established and implemented, some intriguing questions remain unanswered. 1) In what precise mathematical sense is the transformation optics algorithm `exact'? The invariance of Maxwell's equations is well understood, but in what sense does the same principle not apply to acoustics (say)? 2) Even if the fields are transformed in a way that apparently mimic vacuum perfectly, it is easy to construct very simple examples where the impedance of the transformed medium is no longer isotropic and homogeneous. This would seem to imply a fundamental shortcoming in any claim that electromagnetic cloaking has been reduced to technology. 3) Transformations are known to exist that introduce a discrepancy between the Poynting vector and the wave-vector. Does this distinction carry any physical significance? We have worked extensively on understanding a commonality between transformation theories that operates at the level of rays - being interpreted as geodesics of an appropriate manifold. At this level we now understand that the *key* problem underlying all attempts to unify the transformational approach to disparate areas of physics is how to relate the transformation of the base metric (be it Euclidean for spatial transformation optics, or Minkowskian for spacetime transformation optics) to the medium parameters of a given physical domain (e.g. constitutive parameters for electromagnetism, bulk modulus and mass density for acoustics, diffusion constant and number density for diffusion physics). Another misconception we will seek to address is the notion of the relationship between transformation optics and curvature. Many have indicated that transformation optics evinces similarities with Einstein's curvature of spacetime. Here we will show emphatically that transformation optics cannot induce curvature. Inducing curvature in an electromagnetic medium requires the equivalent of a gravitational source. We will propose a scheme
Multiple Manifold Clustering Using Curvature Constrained Path
Babaeian, Amir; Bayestehtashk, Alireza; Bandarabadi, Mojtaba
2015-01-01
The problem of multiple surface clustering is a challenging task, particularly when the surfaces intersect. Available methods such as Isomap fail to capture the true shape of the surface near by the intersection and result in incorrect clustering. The Isomap algorithm uses shortest path between points. The main draw back of the shortest path algorithm is due to the lack of curvature constrained where causes to have a path between points on different surfaces. In this paper we tackle this problem by imposing a curvature constraint to the shortest path algorithm used in Isomap. The algorithm chooses several landmark nodes at random and then checks whether there is a curvature constrained path between each landmark node and every other node in the neighborhood graph. We build a binary feature vector for each point where each entry represents the connectivity of that point to a particular landmark. Then the binary feature vectors could be used as a input of conventional clustering algorithm such as hierarchical clustering. We apply our method to simulated and some real datasets and show, it performs comparably to the best methods such as K-manifold and spectral multi-manifold clustering. PMID:26375819
Effects of wall curvature on turbulence statistics
NASA Technical Reports Server (NTRS)
Moser, R. D.; Moin, P.
1985-01-01
A three-dimensional, time-dependent, direct numerical simulation of low-Reynolds number turbulent flow in a mildly curved channel was performed, and the results examined to determine the mechanism by which curvature affects wall-bounded turbulent shear flows. A spectral numerical method with about one-million modes was employed, and no explicit subgrid scale model was used. The effects of curvature on this flow were determined by comparing the concave and convex sides of the channel. The observed effects are consistent with experimental observations for mild curvature. The most significant difference in the turbulence statistics between the concave and convex sides is in the Reynolds shear stress. This is accompanied by significant differences in the terms of the Reynolds shear stress balance equations. In addition, it was found that stationary Taylor-Goertler vortices were present and that they had a significant effect on the flow by contributing to the mean Reynolds shear stress, and by enhancing the difference between the wall shear stresses.
Superintegrable systems on spaces of constant curvature
Gonera, Cezary Kaszubska, Magdalena
2014-07-15
Construction and classification of two-dimensional (2D) superintegrable systems (i.e. systems admitting, in addition to two global integrals of motion guaranteeing the Liouville integrability, the third global and independent one) defined on 2D spaces of constant curvature and separable in the so-called geodesic polar coordinates are presented. The method proposed is applicable to any value of curvature including the case of Euclidean plane, sphere and hyperbolic plane. The main result is a generalization of Bertrand’s theorem on 2D spaces of constant curvature and covers most of the known separable and superintegrable models on such spaces (in particular, the so-called Tremblay–Turbiner–Winternitz (TTW) and Post–Winternitz (PW) models which have recently attracted some interest). -- Highlights: •Classifying 2D superintegrable, separable (polar coordinates) systems on S{sup 2}, R{sup 2}, H{sup 2}. •Construction of radial, angular potentials leading to superintegrability. •Generalization of Bertrand’s theorem covering known models, e.g. Higgs, TTW, PW, and Coulomb.
Curvature effect on tearing modes in presence of neoclassical friction
Maget, Patrick; Mellet, Nicolas; Meshcheriakov, Dmytro; Garbet, Xavier; Lütjens, Hinrich
2013-11-15
Neoclassical physics (here associated to the poloidal variation of the magnetic field strength along field lines in a tokamak) is well known for driving self-generated plasma current and nonlinear magnetic islands associated to it in high performance, ITER relevant plasma discharges. It is demonstrated that the neoclassical friction between a magnetic perturbation and plasma flow already impacts magnetic islands in the linear regime, by inducing a weakening of curvature stabilization for tearing modes. This conclusion holds in particular for regimes where convection is influencing the pressure dynamics, as shown using a simple analytical model and confirmed in full Magneto-Hydro-Dynamics simulations.
Feature tracking in high-resolution regional climate data
NASA Astrophysics Data System (ADS)
Massey, Neil R.
2016-08-01
In this paper, a suite of algorithms are presented which facilitate the identification and tracking of storm-indicative features, such as mean sea-level pressure minima, in high resolution regional climate data. The methods employ a hierarchical triangular mesh, which is tailored to the regional climate data by only subdividing triangles, from an initial icosahedron, within the domain of the data. The regional data is then regridded to this triangular mesh at each level of the grid, producing a compact representation of the data at numerous resolutions. Storm indicative features are detected by first subtracting the background field, represented by a low resolution version of the data, which occurs at a lower level in the mesh. Anomalies from this background field are detected, as feature objects, at a mesh level which corresponds to the spatial scale of the feature being detected and then refined to the highest mesh level. These feature objects are expanded to an outer contour and overlapping objects are merged. The centre points of these objects are tracked across timesteps by applying an optimisation scheme which uses five hierarchical rules. Objects are added to tracks based on the highest rule in the scheme they pass and, if two objects pass the same rule, the cost of adding the object to the track. An object exchange scheme ensures that adding an object to a track is locally optimal. An additional track optimisation phase is performed which exchanges segments between tracks and merges tracks to obtain a globally optimal track set. To validate the suite of algorithms they are applied to the ERA-Interim reanalysis dataset and compared to other storm-indicative feature tracking algorithms.
Electrodynamic structure of the morning high-latitude trough region
NASA Astrophysics Data System (ADS)
Vanhamäki, H.; Aikio, A.; Voiculescu, M.; Juusola, L.; Nygrén, T.; Kuula, R.
2016-03-01
We describe the electrodynamics of a postmidnight, high-latitude ionospheric trough, observed with the European Incoherent Scatter radar in northern Scandinavia on 24-25 June 2003 around 22:00-02:30 UT during quiet conditions. The UHF radar made meridian scans with a 30 min cadence resulting in nine cross sections of ionospheric parameters. The F region electric field was also determined with the tristatic system. Ionospheric equivalent currents, calculated from ground magnetometer data, mostly show an electrojet-like current that is reasonably uniform in the longitudinal direction. Combined analysis of the conductances and equivalent current with a local Kamide-Richmond-Matsushita (KRM) method yields the ionospheric electric field and field-aligned current (FAC) in a 2-D (latitude-longitude) area around the radar. We conclude that the most likely scenario is one where the trough is initially created poleward of the auroral oval by downward FAC that evacuates the F region, but as the trough moves to lower latitudes during the early morning hours, it becomes colocated with the westward electrojet. There the electron density further decreases due to increased recombination caused by enhanced ion temperature, which in turn is brought about by a larger convection speed. Later in the morning the convection speed decreases and the trough is filled by increasing photoionization.
Regional High Resolution Reanalysis Covered European North East Shelf
NASA Astrophysics Data System (ADS)
Bourdalle-Badie, R.; Benkiran, M.; Chanut, J.; Drillet, Y.; Reffray, G.
2011-12-01
Mercator-Ocean has developed a regional forecasting system at 1/12° resolution over the North East Atlantic (IBI: Iberia, Biscay and Irish), taking advantage of the recent developments in NEMO. This regional forecasting system uses boundary conditions from the Mercator-Ocean global reanalysis (GLORYS: Global Ocean ReanalYses and Simulations). The assimilation component of the Mercator Ocean system, is based on a reduced-order Kalman filter (the SEEK or Singular Extended Evolutive Kalman filter). An IAU method (Incremental Analysis Updates) is used to apply the increments in the system. The error statistics are represented in a sub-space spanned by a small number of dominant 3D error directions. The data assimilation system allows to constrain the model in a multivariate way with Sea Surface Temperature (AVHRR + Multi-satellite High resolution), together with all available satellite Sea Level Anomalies, and with in situ observations from the CORA-03 data base, including ARGO floats temperature and salinity measurements. This reanalysis covers the period from January 2002 to December 2009. In this presentation, the results obtained with this reanalysis system (1/12°) are compared to the GLORYS ones. A special focus will be made on the gain thanks to the higher resolution of the model and higher resolution of the SST assimilated in this reanalysis.
Effects of corotating interaction regions on Ulysses high energy particles
Droege, W.; Kunow, H.; Heber, B.; Mueller-Mellin, R.; Sierks, H.; Wibberenz, G.; Raviart, A.; Ducros, R.; Ferrando, P.; Rastoin, C.; Gosling, J.T.
1996-07-01
We investigate the intensity variation of low energy ({approximately}6{endash}23MeV/N) heliospheric ions and of galactic protons (250{endash}2200 MeV) observed by the Kiel Electron Telescope onboard the Ulysses spacecraft associated with Corotating Interaction Regions (CIR) from mid-1992 to end of June 1995. This period covers Ulysses{close_quote} transit to high southern latitudes, the south polar pass, return to the solar equator and ascent to the north pole up to 70{degree}. We find that the flux of high energy protons exhibits a periodicity of about 26 days with a relative intensity variation of 10{percent}. At latitudes below {approximately}50{degree} the recurrent variations of galactic protons are in coincidence with the passage of CIRs and enhancements of low energies protons and alpha particles which are accelerated at the shocks of the CIRs. The modulation of galactic protons is observed up to high southern latitudes, where the signatures of a CIR are no longer visible in plasma or magnetic field data. The periodicity does not depend on latitude and its phase apparently remains constant during Ulysses{close_quote} pass over the south pole as well as through the solar equator. {copyright} {ital 1996 American Institute of Physics.}
Effects of corotating interaction regions on Ulysses high energy particles
Droege, W.; Kunow, H.; Heber, B.; Mueller-Mellin, R.; Sierks, H.; Wibberenz, G.; Raviart, A.; Ducros, R.; Ferrando, P.; Rastoin, C.; Paizis, C.; Gosling, J. T.
1996-07-20
We investigate the intensity variation of low energy ({approx}6-23 MeV/N) heliospheric ions and of galactic protons (250-2200 MeV) observed by the Kiel Electron Telescope onboard the Ulysses spacecraft associated with Corotating Interaction Regions (CIR) from mid-1992 to end of June 1995. This period covers Ulysses' transit to high southern latitudes, the south polar pass, return to the solar equator and ascent to the north pole up to 70 deg. We find that the flux of high energy protons exhibits a periodicity of about 26 days with a relative intensity variation of 10%. At latitudes below {approx}50 deg. the recurrent variations of galactic protons are in coincidence with the passage of CIRs and enhancements of low energies protons and alpha particles which are accelerated at the shocks of the CIRs. The modulation of galactic protons is observed up to high southern latitudes, where the signatures of a CIR are no longer visible in plasma or magnetic field data. The periodicity does not depend on latitude and its phase apparently remains constant during Ulysses' pass over the south pole as well as through the solar equator.
State switching in regions of high modal density
NASA Astrophysics Data System (ADS)
Lopp, Garrett K.; Kauffman, Jeffrey L.
2016-04-01
Performance of piezoelectric-based, semi-active vibration reduction approaches has been studied extensively in the past decade. Originally analyzed with single-degree-of-freedom systems, these approaches have been extended to multi-mode vibration reduction. However, the accompanying analysis typically assumes well-separated modes, which is often not the case for plate structures. Because the semi-active approaches induce a shift in the structural resonance frequency (at least temporarily), targeting a speciﬁc mode for vibration reduction can actually lead to additional vibration in an adjacent mode. This paper presents an analysis using a simpliﬁed model of a two-degree-of-freedom mass-spring-damper system with lightly-coupled masses to achieve two closely-spaced modes. This investigation is especially applicable to the resonance frequency detuning approach previously proposed to reduce vibrations caused by transient excitation in turbomachinery blades where regions of high modal density exist. More generally, this paper addresses these eﬀects of stiﬀness state switches in frequency ranges containing regions of high modal density and subject to frequency sweep excitation. Of the approaches analyzed, synchronized switch damping on an inductor oﬀers the greatest vibration reduction performance, whereas resonance frequency detuning and state switching each yield similar performance. Additionally, as the relative distance between resonance peaks decreases, the performance for the vibration reduction methods approaches that of a single-degree-of-freedom system; however, there are distances between these resonant peaks that diminish vibration reduction potential.
NASA Astrophysics Data System (ADS)
Zhao, Hui; Fan, Xuewu; Pang, Zhihai; Ren, Guorui; Wang, Wei; Xie, Yongjie; Ma, Zhen; Du, Yunfei; Su, Yu; Wei, Jingxuan
2015-02-01
In recent years, optical zoom imaging without moving elements has received much attention. The key to realizing this technique lies in the design of the variable-curvature mirror (VCM). To obtain enough optical magnification, the VCM should be able to change its radius of curvature over a wide range. In other words, the VCM must be able to provide a large sagittal variation, which requires the mirror material to be robust during curvature variation, require little force to deform, and have high ultimate strength. Carbon-fiber-reinforced polymer (CFRP) satisfies all these requirements and is suitable for fabricating such a VCM. Therefore, in this research, a CFRP prototype VCM has been designed, fabricated, and tested. With a diameter of 100 mm, a thickness of 2 mm, and an initial radius of curvature of 1740 mm, this VCM can provide a maximum 23-μm sagittal variation and a minimum and maximum radius of curvature of 1705 and 1760 mm.
Regional Climate Modeling over the Glaciated Regions of the Canadian High Arctic
NASA Astrophysics Data System (ADS)
Gready, Benjamin P.
The Canadian Arctic Islands (CAI) contain the largest concentration of terrestrial ice outside of the continental ice sheets. Mass loss from this region has recently increased sharply due to above average summer temperatures. Thus, increasing the understanding of the mechanisms responsible for mass loss from this region is critical. Previously, Regional Climate Models (RCMs) have been utilized to estimate climatic balance over Greenland and Antarctica. This method offers the opportunity to study a full suite of climatic variables over extensive spatially distributed grids. However, there are doubts of the applicability of such models to the CAI, given the relatively complex topography of the CAI. To test RCMs in the CAI, the polar version of the regional climate model MM5 was run at high resolution over Devon Ice Cap. At low altitudes, residuals (computed through comparisons with in situ measurements) in the net radiation budget were driven primarily by residuals in net shortwave (NSW) radiation. Residuals in NSW are largely due to inaccuracies in modeled cloud cover and modeled albedo. Albedo on glaciers and ice sheets is oversimplified in Polar MM5 and its successor, the Polar version of the Weather Research and Forecast model (Polar WRF), and is an obvious place for model improvement. Subsequently, an inline parameterization of albedo for Polar WRF was developed as a function of the depth, temperature and age of snow. The parameterization was able to reproduce elevation gradients of seasonal mean albedo derived from satellite albedo measurements (MODIS MOD10A1 daily albedo), on the western slope of the Greenland Ice Sheet for three years. Feedbacks between modelled albedo and modelled surface energy budget components were identified. The shortwave radiation flux feeds back positively with changes to albedo, whereas the longwave, turbulent and ground energy fluxes all feed back negatively, with a maximum combined magnitude of two thirds of the shortwave feedback
Reeves, Matthew; Stratford, Kevin; Thijssen, Job H J
2016-05-14
Bicontinuous Pickering emulsions (bijels) are a physically interesting class of soft materials with many potential applications including catalysis, microfluidics and tissue engineering. They are created by arresting the spinodal decomposition of a partially-miscible liquid with a (jammed) layer of interfacial colloids. Porosity L (average interfacial separation) of the bijel is controlled by varying the radius (r) and volume fraction (ϕ) of the colloids (L∝r/ϕ). However, to optimize the bijel structure with respect to other parameters, e.g. quench rate, characterizing by L alone is insufficient. Hence, we have used confocal microscopy and X-ray CT to characterize a range of bijels in terms of local and area-averaged interfacial curvatures; we further demonstrate that bijels are bicontinuous using an image-analysis technique known as 'region growing'. In addition, the curvatures of bijels have been monitored as a function of time, which has revealed an intriguing evolution up to 60 minutes after bijel formation, contrary to previous understanding. PMID:27035101
Controls on thrust belt curvature, Wyoming-Idaho thrust belt
Montgomery, J.M. Jr. . Dept. of Geological Sciences)
1993-04-01
Structural curvature in the northern part of the Wyoming-Idaho thrust belt (WITB) may be the result of either along-strike variations in pre-thrust stratigraphy or a buttress which physically concentrated shortening, or possibly both. Most thrust sheets of the WITB strike northward and were translated eastward, but in the Snake River Range (SRR) (the northernmost range in the WITB), structural strike curves from northward to nearly westward. Structural cross sections of the SRR are generally drawn in a radial pattern creating a volumetric imbalance in regional palinspastic restorations. Stratigraphic separation diagrams of major, through-going thrust faults in the SRR show extensive cut off in upper Paleozoic strata. New measured sections of upper Paleozoic stratigraphy at locations in several major thrust sheets of the WITB and in the foreland, new structural cross sections and mapping, and existing paleomagnetic data are used in a new interpretation of the origin of structural curvature in the WITB. Published paleomagnetic data require counterclockwise rotation of frontal thrust sheets along the northern boundary of the WITB, but no rotation of eastward-translated thrust sheets farther south along most of the WITB. Evidence for both a pre-existing west-trending depositional margin and rotation of frontal thrust sheets suggests that buttressing and modification of structural strike occurred along an oblique ramp where differences in stratigraphic thickness and possible pre-existing fault partitioning of the Paleozoic strata are localized.
Alterations in braided rivers' morphology: a typology for Curvature Subcarpathians (Romania)
NASA Astrophysics Data System (ADS)
Ioana-Toroimac, Gabriela; Zaharia, Liliana; Ciobotaru, Nicu
2015-04-01
The morphology of braided rivers was altered by human pressures in the last century in Europe. Rivers from Curvature Subcarpathians have the highest sediment charges in Romania, therefore it seems relevant to evaluate the status of their braided sectors. Therefore, the aim of this work is to carry out an inventory of river morphology alterations suffered by braided rivers in Curvature Subcarpathians and to establish a typology based on indicators for channel adjustments and artificiality. For channel adjustments, we calculated the length of the braided sectors, the width of the active-channels and the length of banks covered by a riparian forest for 1900-2011 interval, in GIS. For artificiality, we counted dams, weirs, bridges, as well as artificial banks length for 2011 time horizon. The results indicate a diminishing braiding activity: all the rivers narrowed their braided active-channel (30-70% of the mean width); the majority suffered fluvial metamorphosis, transforming partially into single channels (0-75% of the braided sector length in 1900); artificial banks vary from 0 to 40% of the initial braided sector. We distinguished three main types of braided rivers based on morphological alterations. Type 1 includes rivers with human interventions and important braiding retraction, both upstream and downstream; a sub-type characterises by riparian forest lining the downstream metamorphosed reach; most rivers are in the south-western part of the studied region; the most demonstrative examples are Prahova and Ialomiţa rivers. Type 2 corresponds to rivers with important retraction upstream, without important values of artificiality; most demonstrative is Râmna River. Type 3 regroups rivers with a low level of channel adjustments and artificiality; actually, they had and still have the highest braiding activity in the studied region; they are located in the north-eastern part; typical examples are Putna and Şuşiţa rivers. As a discussion, the variations of active
Stable hypersurfaces with zero scalar curvature in Euclidean space
NASA Astrophysics Data System (ADS)
Alencar, Hilário; do Carmo, Manfredo; Neto, Gregório Silva
2016-04-01
In this paper we prove some results concerning stability of hypersurfaces in the four dimensional Euclidean space with zero scalar curvature. First we prove there is no complete stable hypersurface with zero scalar curvature, polynomial growth of integral of the mean curvature, and with the Gauss-Kronecker curvature bounded away from zero. We conclude this paper giving a sufficient condition for a regular domain to be stable in terms of the mean and the Gauss-Kronecker curvatures of the hypersurface and the radius of the smallest extrinsic ball which contains the domain.
Distributed mean curvature on a discrete manifold for Regge calculus
NASA Astrophysics Data System (ADS)
Conboye, Rory; Miller, Warner A.; Ray, Shannon
2015-09-01
The integrated mean curvature of a simplicial manifold is well understood in both Regge Calculus and Discrete Differential Geometry. However, a well motivated pointwise definition of curvature requires a careful choice of the volume over which to uniformly distribute the local integrated curvature. We show that hybrid cells formed using both the simplicial lattice and its circumcentric dual emerge as a remarkably natural structure for the distribution of this local integrated curvature. These hybrid cells form a complete tessellation of the simplicial manifold, contain a geometric orthonormal basis, and are also shown to give a pointwise mean curvature with a natural interpretation as the fractional rate of change of the normal vector.
The role of curvature of ionospheric irregularities in transequatorial propagation at VHF
NASA Astrophysics Data System (ADS)
Ferguson, J. A.
The role of curvature of ionospheric irregularities in transequatorial propagation at VHF is investigated by adapting the theory of spread by Booker and Ferguson (1978), which employs backscattering from long field-aligned irregularities of ionization in the F-region. The new theory involves scattering by irregularities in planes perpendicular to the earth's magnetic field combined with coherent behavior along each field line. Results prove sufficient to explain the signal strengths observed experimentally, and in the case of transequatorial scattering, curvature of the field lines results in caustics and foci.
Small-Scale High-Temperature Structures in Flare Regions
NASA Astrophysics Data System (ADS)
Kovalev, V. A.; Chernov, G. P.; Hanaoka, I.
2001-04-01
When analyzing YOHKOH/SXT, HXT (soft and hard X-ray) images of solar flares against the background of plasma with a temperature T ~ 6 MK, we detected localized (with minimum observed sizes of approximately 2000 km) high-temperature structures (HTSs) with T = (20-50) MK with a complex spatial-temporal dynamics. Quasi-stationary, stable HTSs form a chain of hot cores that encircles the flare region and coincides with the magnetic loop. No structures are seen in the emission measure. We reached conclusions about the reduced heat conductivity (a factor of ~10^3 lower than the classical isotropic one) and high thermal insulation of HTSs. The flare plasma becomes collisionless in the hottest HTSs (T > 20 MK). We confirm the previously investigated idea of spatial heat localization in the solar atmosphere in the form of HTSs during flare heating with a volume nonlocalized source. Based on localized soliton solutions of a nonlinear heat conduction equation with a generalized flare-heating source of a potential form including radiative cooling, we discuss the nature of HTSs.
The role of Gauss curvature in a membrane phase separation problem
NASA Astrophysics Data System (ADS)
Gillmor, Susan; Lee, Jieun; Ren, Xiaofeng
2011-12-01
Consider a two-phase lipid vesicle. Below the transition temperature, the phases separate into non-connecting domains that coarsen into larger areas. The free energy of phase properties determines the length of the boundaries separating the regions. The two phases correspond to different lipid compositions, and in cells, this fluctuation in composition is a dynamic process vital to its function. We prove that a small patch of the minority lipids forms at a point of the membrane where the Gauss curvature attains a maximum. This patch has a round shape approximately and its boundary has a constant geodesic curvature. The proof consists of three steps. The construction of a family of good approximate solutions, an improvement of the approximate solutions so that their geodesic curvature is a constant modulo translation, and the identification of an exact solution from the family of the improved approximate solutions. Our theoretical results are supported by vesicle experiments.
A reflection ansatz for surfaces with electrically small radii of curvature
NASA Technical Reports Server (NTRS)
Dominek, Allen K.; Peters, Leon, Jr.; Burnside, Walter D.
1987-01-01
Uniform reflection coefficients are developed for two- and three-dimensional, edge-like, perfectly conducting surfaces in the deep lit region. The uniformity is with respect to the electrical size of the radii of curvature at the surface's specular point. This uniformity allows one to physically interpret the reflected field from a smooth surface as one of the radii of curvature approaches zero as a diffracted field. The coefficients are heuristically generated from the exact scattered field for a two dimensional parabolic cylinder with plane wave illumination. The significant variables in this solution are the radii of curvature at the specular point and the distance between the specular point and the incident shadow boundaries in the principal planes. The field prediction accuracy of these reflection cofficients are critically examined through comparisons with reflected fields extracted from scattered fields of canonical surfaces.
Impact of High Resolution SST Data on Regional Weather Forecasts
NASA Technical Reports Server (NTRS)
Jedlovec, Gary J.; Case, Jonathon; LaFontaine, Frank; Vazquez, Jorge; Mattocks, Craig
2010-01-01
Past studies have shown that the use of coarse resolution SST products such as from the real-time global (RTG) SST analysis[1] or other coarse resolution once-a-day products do not properly portray the diurnal variability of fluxes of heat and moisture from the ocean that drive the formation of low level clouds and precipitation over the ocean. For example, the use of high resolution MODIS SST composite [2] to initialize the Advanced Research Weather Research and Forecast (WRF) (ARW) [3] has been shown to improve the prediction of sensible weather parameters in coastal regions [4][5}. In an extend study, [6] compared the MODIS SST composite product to the RTG SST analysis and evaluated forecast differences for a 6 month period from March through August 2007 over the Florida coastal regions. In a comparison to buoy data, they found that that the MODIS SST composites reduced the bias and standard deviation over that of the RTG data. These improvements led to significant changes in the initial and forecasted heat fluxes and the resulting surface temperature fields, wind patterns, and cloud distributions. They also showed that the MODIS composite SST product, produced for the Terra and Aqua satellite overpass times, captured a component of the diurnal cycle in SSTs not represented in the RTG or other one-a-day SST analyses. Failure to properly incorporate these effects in the WRF initialization cycle led to temperature biases in the resulting short term forecasts. The forecast impact was limited in some situations however, due to composite product inaccuracies brought about by data latency during periods of long-term cloud cover. This paper focuses on the forecast impact of an enhanced MODIS/AMSR-E composite SST product designed to reduce inaccuracies due data latency in the MODIS only composite product.
NASA Astrophysics Data System (ADS)
Oikawa, P. Y.; Ge, C.; Wang, J.; Eberwein, J. R.; Liang, L. L.; Allsman, L. A.; Grantz, D. A.; Jenerette, G. D.
2015-11-01
Fertilized soils have large potential for production of soil nitrogen oxide (NOx=NO+NO2), however these emissions are difficult to predict in high-temperature environments. Understanding these emissions may improve air quality modelling as NOx contributes to formation of tropospheric ozone (O3), a powerful air pollutant. Here we identify the environmental and management factors that regulate soil NOx emissions in a high-temperature agricultural region of California. We also investigate whether soil NOx emissions are capable of influencing regional air quality. We report some of the highest soil NOx emissions ever observed. Emissions vary nonlinearly with fertilization, temperature and soil moisture. We find that a regional air chemistry model often underestimates soil NOx emissions and NOx at the surface and in the troposphere. Adjusting the model to match NOx observations leads to elevated tropospheric O3. Our results suggest management can greatly reduce soil NOx emissions, thereby improving air quality.
Oikawa, P Y; Ge, C; Wang, J; Eberwein, J R; Liang, L L; Allsman, L A; Grantz, D A; Jenerette, G D
2015-01-01
Fertilized soils have large potential for production of soil nitrogen oxide (NOx=NO+NO2), however these emissions are difficult to predict in high-temperature environments. Understanding these emissions may improve air quality modelling as NOx contributes to formation of tropospheric ozone (O3), a powerful air pollutant. Here we identify the environmental and management factors that regulate soil NOx emissions in a high-temperature agricultural region of California. We also investigate whether soil NOx emissions are capable of influencing regional air quality. We report some of the highest soil NOx emissions ever observed. Emissions vary nonlinearly with fertilization, temperature and soil moisture. We find that a regional air chemistry model often underestimates soil NOx emissions and NOx at the surface and in the troposphere. Adjusting the model to match NOx observations leads to elevated tropospheric O3. Our results suggest management can greatly reduce soil NOx emissions, thereby improving air quality. PMID:26556236
Oikawa, P. Y.; Ge, C.; Wang, J.; Eberwein, J. R.; Liang, L. L.; Allsman, L. A.; Grantz, D. A.; Jenerette, G. D.
2015-01-01
Fertilized soils have large potential for production of soil nitrogen oxide (NOx=NO+NO2), however these emissions are difficult to predict in high-temperature environments. Understanding these emissions may improve air quality modelling as NOx contributes to formation of tropospheric ozone (O3), a powerful air pollutant. Here we identify the environmental and management factors that regulate soil NOx emissions in a high-temperature agricultural region of California. We also investigate whether soil NOx emissions are capable of influencing regional air quality. We report some of the highest soil NOx emissions ever observed. Emissions vary nonlinearly with fertilization, temperature and soil moisture. We find that a regional air chemistry model often underestimates soil NOx emissions and NOx at the surface and in the troposphere. Adjusting the model to match NOx observations leads to elevated tropospheric O3. Our results suggest management can greatly reduce soil NOx emissions, thereby improving air quality. PMID:26556236
High-resolution mantle tomography of China and surrounding regions
NASA Astrophysics Data System (ADS)
Huang, Jinli; Zhao, Dapeng
2006-09-01
A high-resolution P wave tomographic model of the crust and mantle down to 1100 km depth under China and surrounding regions is determined by using about one million arrival times of P, pP, PP, and PcP waves from 19,361 earthquakes recorded by 1012 seismic stations. The subducting Pacific slab is imaged clearly as a high-velocity zone from the oceanic trenches down to about 600 km depth, and intermediate-depth and deep earthquakes are located within the slab. The Pacific slab becomes stagnant in the mantle transition zone under east China. The western edge of the stagnant slab is roughly coincident with a surface topographic boundary in east China. The active Changbai and Wudalianchi intraplate volcanoes in northeast China are underlain by significant slow anomalies in the upper mantle, above the stagnant Pacific slab. These results suggest that the active intraplate volcanoes in NE China are not hot spots but a kind of back-arc volcano associated with the deep subduction of the Pacific slab and its stagnancy in the transition zone. Under the Mariana arc, however, the Pacific slab penetrates directly down to the lower mantle. The active Tengchong volcano in southwest China is related to the eastward subduction of the Burma microplate. The subducting Indian and Philippine Sea plates are also imaged clearly. The Indian plate has subducted down to 200-300 km depth under the Tibetan Plateau with a horizontal moving distance of about 500 km. High-velocity anomalies are revealed in the upper mantle under the Tarim basin, Ordos, and Sichuan basin, which are three stable blocks in China.
Asymmetrical in-fiber Mach-Zehnder interferometer for curvature measurement.
Sun, Bing; Huang, Yijian; Liu, Shen; Wang, Chao; He, Jun; Liao, Changrui; Yin, Guolu; Zhao, Jing; Liu, Yinjie; Tang, Jian; Zhou, Jiangtao; Wang, Yiping
2015-06-01
We demonstrated a compact and highly-sensitive curvature sensor based on a Mach-Zehnder interferometer created in a photonic crystal fiber. Such a Mach-Zehnder interferometer consisted of a peanut-like section and an abrupt taper achieved by use of an optimized electrical arc discharge technique, where only one dominating cladding mode was excited and interfered with the fundamental mode. The unique structure exhibited a high curvature sensitivity of 50.5 nm/m^{-1} within a range from 0 to 2.8 m^{-1}, which made it suitable for high-sensitivity curvature sensing in harsh environments. Moreover, it also exhibited a temperature sensitivity of 11.7 pm/°C. PMID:26072819
Plasma simulations of emission line regions in high energy environments
NASA Astrophysics Data System (ADS)
Richardson, Chris T.
This dissertation focuses on understanding two different, but in each case extreme, astrophysical environments: the Crab Nebula and emission line galaxies. These relatively local objects are well constrained by observations and are test cases of phenomena seen at high-z where detailed observations are rare. The tool used to study these objects is the plasma simulation code known as Cloudy. The introduction provides a brief summary of relevant physical concepts in nebular astrophysics and presents the basic features and assumptions of Cloudy. The first object investigated with Cloudy, the Crab Nebula, is a nearby supernova remnant that previously has been subject to photoionization modeling to reproduce the ionized emission seen in the nebula's filamentary structure. However, there are still several unanswered questions: (1) What excites the H2 emitting gas? (2) How much mass is in the molecular component? (3) How did the H2 form? (4) What is nature of the dust grains? A large suite of observations including long slit optical and NIR spectra over ionized, neutral and molecular gas in addition to HST and NIR ground based images constrain a particularly bright region of H2 emission, Knot 51, which exhibits a high excitation temperature of ˜3000 K. Simulations of K51 revealed that only a trace amount of H2 is needed to reproduce the observed emission and that H2 forms through an uncommon nebular process known as associative detachment. The final chapters of this dissertation focus on interpreting the narrow line region (NLR) in low-z emission line galaxies selected by a novel technique known as mean field independent component analysis (MFICA). A mixture of starlight and radiation from an AGN excites the gas present in galaxies. MFICA separates galaxies over a wide range of ionization into subsets of pure AGN and pure star forming galaxies allowing simulations to reveal the properties responsible for their observed variation in ionization. Emission line ratios can
Beddoes, Charlotte M; Berge, Johanna; Bartenstein, Julia E; Lange, Kathrin; Smith, Andrew J; Heenan, Richard K; Briscoe, Wuge H
2016-07-13
Using high pressure small angle X-ray scattering (HP-SAXS), we have studied monoolein (MO) mesophases at 18 wt% hydration in the presence of 10 nm silica nanoparticles (NPs) at NP-lipid number ratios (ν) of 1 × 10(-6), 1 × 10(-5) and 1 × 10(-4) over the pressure range 1-2700 bar and temperature range 20-60 °C. In the absence of the silica NPs, the pressure-temperature (p-T) phase diagram of monoolein exhibited inverse bicontinuous cubic gyroid (Q), lamellar alpha (Lα), and lamellar crystalline (Lc) phases. The addition of the NPs significantly altered the p-T phase diagram, changing the pressure (p) and the temperature (T) at which the transitions between these mesophases occurred. In particular, a strong NP concentration effect on the mesophase behaviour was observed. At low NP concentration, the p-T region pervaded by the Q phase and the Lα-Q mixture increased, and we attribute this behaviour to the NPs forming clusters at the mesophase domain boundaries, encouraging transition to the mesophase with a higher curvature. At high NP concentrations, the Q phase was no longer observed in the p-T phase diagram. Instead, it was dominated by the lamellar (L) phases until the transition to a fluid isotropic (FI) phase at 60 °C at low pressure. We speculate that NPs formed aggregates with a "chain of pearls" structure at the mesophase domain boundaries, hindering transitions to the mesophases with higher curvatures. These observations were supported by small angle neutron scattering (SANS) and scanning electron microscopy (SEM). Our results have implications to nanocomposite materials and nanoparticle cellular entry where the interactions between NPs and organised lipid structures are an important consideration. PMID:27340807
The curvature adaptive optics system modeling
NASA Astrophysics Data System (ADS)
Yang, Qiang
A curvature adaptive optics (AO) simulation system has been built. The simulation is based on the Hokupa'a-36 AO system for the NASA IRTF 3m telescope and the Hokupa'a-85 AO system for the Gemini Near Infrared Coronagraphic Imager. Several sub-models are built separately for the AO simulation system, and they are: (1) generation and propagation of atmospheric phase screens, (2) the bimorph deformable mirror (DM), (3) the curvature wave-front sensor (CWFS), (4) generation of response functions, interaction matrices and calculation of command matrices, (5) Fresnel propagation from the DM pupil to the lenslet pupil, (6) AO servo loop, and (7) post processing. The AO simulation system is then applied to the effects of DM hysteresis, and to the optimization of DM actuator patterns for the Hokupa'a-85 and Hokupa'a-36 AO systems. In the first application, an enhancing Coleman-Hodgdon model is introduced to approximate the hysteresis curves, and then the Lambert W function is introduced to calculate the inverse of the Coleman-Hodgdon equation. Step response, transfer functions and Strehl Ratios from the AO system have been compared under the cases with/without DM hysteresis. The servo-loop results show that the bandwidth of an AO system is improved greatly after the DM hysteresis is corrected. In the second application, many issues of the bimorph mirror will be considered to optimize the DM patterns, and they include the type and length of the edge benders, gap size of electrodes, DM size, and DM curvature limit.
Evapotranspiration mapping using METRIC for a region with highly advective conditions
Technology Transfer Automated Retrieval System (TEKTRAN)
Agriculture in the Texas High Plains accounts for approximately 92% of groundwater withdrawals. Because, groundwater levels are declining in the region, efficient agricultural water use is imperative for sustainability and regional economic viability. Accurate regional evapotranspiration (ET) maps w...
Curvature sensors: noise and its propagation.
Kellerer, Aglae
2010-11-01
The signal measured with a curvature sensor is analyzed. At the outset, we derive the required minimum number of sensing elements at the pupil edges, depending on the total number of sensing elements. The distribution of the sensor signal is further characterized in terms of its mean, variance, kurtosis, and skewness. It is established that while the approximation in terms of a Gaussian distribution is correct down to fairly low photon numbers, much higher numbers are required to obtain meaningful sensor measurements for small wavefront distortions. Finally, we indicate a closed expression for the error propagation factor and for the photon-noise-induced Strehl loss. PMID:21045888
Constant mean curvature foliations in cosmological spacetimes.
NASA Astrophysics Data System (ADS)
Rendall, A. D.
1996-11-01
Foliations by constant mean curvature hypersurfaces provide a possibility of defining a preferred time coordinate in general relativity. In the following various conjectures are made about the existence of foliations of this kind in spacetimes satisfying the strong energy condition and possessing compact Cauchy hypersurfaces. Recent progress on proving these conjectures under supplementary assumptions is reviewed. The method of proof used is explained and the prospects for generalizing it discussed. The relations of these questions to cosmic censorship and the closed universe recollapse conjecture are pointed out.
Negative Gaussian curvature from induced metric changes.
Modes, Carl D; Warner, Mark
2015-07-01
We revisit the light or heat-induced changes in topography of initially flat sheets of a solid that elongate or contract along patterned in-plane director fields. For radial or azimuthal directors, negative Gaussian curvature is generated-so-called "anticones." We show that azimuthal material displacements are required for the distorted state to be stretch free and bend minimizing. The resultant shapes are smooth and asterlike and can become reentrant in the azimuthal coordinate for large deformations. We show that care is needed when considering elastomers rather than glasses, although the former offer huge deformations. PMID:26274106
Curvature and temperature of complex networks
NASA Astrophysics Data System (ADS)
Krioukov, Dmitri; Papadopoulos, Fragkiskos; Vahdat, Amin; Boguñá, Marián
2009-09-01
We show that heterogeneous degree distributions in observed scale-free topologies of complex networks can emerge as a consequence of the exponential expansion of hidden hyperbolic space. Fermi-Dirac statistics provides a physical interpretation of hyperbolic distances as energies of links. The hidden space curvature affects the heterogeneity of the degree distribution, while clustering is a function of temperature. We embed the internet into the hyperbolic plane and find a remarkable congruency between the embedding and our hyperbolic model. Besides proving our model realistic, this embedding may be used for routing with only local information, which holds significant promise for improving the performance of internet routing.
Curvature sensor for ocular wavefront measurement.
Díaz-Doutón, Fernando; Pujol, Jaume; Arjona, Montserrat; Luque, Sergio O
2006-08-01
We describe a new wavefront sensor for ocular aberration determination, based on the curvature sensing principle, which adapts the classical system used in astronomy for the living eye's measurements. The actual experimental setup is presented and designed following a process guided by computer simulations to adjust the design parameters for optimal performance. We present results for artificial and real young eyes, compared with the Hartmann-Shack estimations. Both methods show a similar performance for these cases. This system will allow for the measurement of higher order aberrations than the currently used wavefront sensors in situations in which they are supposed to be significant, such as postsurgery eyes. PMID:16832447
Double curvature mirrors for linear concentrators
NASA Astrophysics Data System (ADS)
Lance, Tamir; Ackler, Harold; Finot, Marc
2012-10-01
Skyline Solar's medium concentration photovoltaic system uses quasi-parabolic mirrors and one axis tracking. Improvements in levelized cost of energy can be achieved by effective management of non-uniformity of the flux line on the panels. To reduce non uniformity of the flux line due to mirror to mirror gaps, Skyline developed a dual curvature mirror that stretches the flux line along the panel. Extensive modeling and experiments have been conducted to analyze the impact of this new design and to optimize the design.
Holographic entropy increases in quadratic curvature gravity
NASA Astrophysics Data System (ADS)
Bhattacharjee, Srijit; Sarkar, Sudipta; Wall, Aron C.
2015-09-01
Standard methods for calculating the black hole entropy beyond general relativity are ambiguous when the horizon is nonstationary. We fix these ambiguities in all quadratic curvature gravity theories, by demanding that the entropy be increasing at every time, for linear perturbations to a stationary black hole. Our result matches with the entropy formula found previously in holographic entanglement entropy calculations. We explicitly calculate the entropy increase for Vaidya-like solutions in Ricci-tensor gravity to show that (unlike the Wald entropy) the holographic entropy obeys a second law.
Steering electromagnetic beams with conical curvature singularities.
Zhang, Yong-Liang; Dong, Xian-Zi; Zheng, Mei-Ling; Zhao, Zhen-Sheng; Duan, Xuan-Ming
2015-10-15
We describe how the transformation-optics technique can be used to design an effective medium mimicking the conical curvature singularity. Anholonomic coordinate transformation gives rise to linear topological defects that break the rotational symmetry. The bending and splitting of the optical beams are found analytically and numerically, depending on the incident direction and the topological charge. Beyond their practical applications to omnidirectional beam steering for photonics, our findings set forth an attractive realm to simulate the relevant physical phenomena in the optical laboratory. PMID:26469619
Temporal changes in greenspace in a highly urbanized region
Dallimer, Martin; Tang, Zhiyao; Bibby, Peter R.; Brindley, Paul; Gaston, Kevin J.; Davies, Zoe G.
2011-01-01
The majority of the world's population now lives in towns and cities, and urban areas are expanding faster than any other land-use type. In response to this phenomenon, two opposing arguments have emerged: whether cities should ‘sprawl’ into the wider countryside, or ‘densify’ through the development of existing urban greenspace. However, these greenspaces are increasingly recognized as being central to the amelioration of urban living conditions, supporting biodiversity conservation and ecosystem service provision. Taking the highly urbanized region of England as a case study, we use data from a variety of sources to investigate the impact of national-level planning policy on temporal patterns in the extent of greenspace in cities. Between 1991 and 2006, greenspace showed a net increase in all but one of 13 cities. However, the majority of this gain occurred prior to 2001, and greenspace has subsequently declined in nine cities. Such a dramatic shift in land use coincides with policy reforms in 2000, which favoured densification. Here, we illustrate the dynamic and policy-responsive nature of urban land use, thereby highlighting the need for a detailed investigation of the trade-offs associated with different mechanisms of urban densification to optimize and secure the diverse benefits associated with greenspaces. PMID:21429910
Temporal changes in greenspace in a highly urbanized region.
Dallimer, Martin; Tang, Zhiyao; Bibby, Peter R; Brindley, Paul; Gaston, Kevin J; Davies, Zoe G
2011-10-23
The majority of the world's population now lives in towns and cities, and urban areas are expanding faster than any other land-use type. In response to this phenomenon, two opposing arguments have emerged: whether cities should 'sprawl' into the wider countryside, or 'densify' through the development of existing urban greenspace. However, these greenspaces are increasingly recognized as being central to the amelioration of urban living conditions, supporting biodiversity conservation and ecosystem service provision. Taking the highly urbanized region of England as a case study, we use data from a variety of sources to investigate the impact of national-level planning policy on temporal patterns in the extent of greenspace in cities. Between 1991 and 2006, greenspace showed a net increase in all but one of 13 cities. However, the majority of this gain occurred prior to 2001, and greenspace has subsequently declined in nine cities. Such a dramatic shift in land use coincides with policy reforms in 2000, which favoured densification. Here, we illustrate the dynamic and policy-responsive nature of urban land use, thereby highlighting the need for a detailed investigation of the trade-offs associated with different mechanisms of urban densification to optimize and secure the diverse benefits associated with greenspaces. PMID:21429910
Annular force based variable curvature mirror aiming to realize non-moving element optical zooming
NASA Astrophysics Data System (ADS)
Zhao, Hui; Xie, Xiaopeng; Wei, Jingxuan; Ren, Guorui; Pang, Zhihai; Xu, Liang
2015-10-01
Recently, a new kind of optical zooming technique in which no moving elements are involved has been paid much attention. The elimination of moving elements makes optical zooming suitable for applications which has exacting requirements in space, power cost and system stability. The mobile phone and the space-borne camera are two typical examples. The key to realize non-moving elements optical zooming lies in the introduction of variable curvature mirror (VCM) whose radius of curvature could be changed dynamically. When VCM is about to be used to implement optical zoom imaging, two characteristics should be ensured. First, VCM has to provide large enough saggitus variation in order to obtain a big magnification ratio. Second, after the radius of curvature has been changed, the corresponding surface figure accuracy should still be maintained superior to a threshold level to make the high quality imaging possible. In this manuscript, based on the elasticity theory, the physical model of the annular force based variable curvature mirror is established and numerically analyzed. The results demonstrate that when the annular force is applied at the half-the-aperture position, the actuation force is reduced and a smaller actuation force is required to generate the saggitus variation and thus the maintenance of surface figure accuracy becomes easier during the variation of radius of curvature. Besides that, a prototype VCM, whose diameter and thickness are 100mm and 3mm respectively, have been fabricated and the maximum saggitus variation that could be obtained approaches more than 30 wavelengths. At the same time, the degradation of surface figure accuracy is weakly correlated to the curvature radius variation. Keywords: optical zooming; variable curvature mirror; surface figure accuracy; saggitus;
Numerical analysis of corneal curvature dynamics based on Corvis tonometer images.
Kasprzak, Henryk; Boszczyk, Agnieszka
2016-05-01
The paper presents numerical analysis of corneal curvature distribution, based on Corvis ST images. It was shown that a new approach to analysis of corneal curvature from tonometer images enables a better description and understanding of processes during fast corneal deformation. Ten healthy volunteers participated in nine repeated measurements on one eye. 90 sequences of images were processed with software written in Matlab, with the use of the Image Processing Toolbox. Time-spatial distribution of the local curvature distribution of the corneal profile was obtained for each and every measurement. Some new curvature parameters were proposed and analyzed. A high repeatability for individual subjects was obtained for the proposed parameters. For four of these new parameters, the ICC coefficients were higher than 0.85. The ICC value for the calculated curvature of the cornea before deformation reaches 0.989. Such high repeatability of the proposed new parameters can be useful in examination and differentiation of corneas due to their geometrical and biomechanical properties. PMID:26997615
Turbulent boundary layers subjected to multiple curvatures and pressure gradients
NASA Technical Reports Server (NTRS)
Bandyopadhyay, Promode R.; Ahmed, Anwar
1993-01-01
The effects of abruptly applied cycles of curvatures and pressure gradients on turbulent boundary layers are examined experimentally. Two two-dimensional curved test surfaces are considered: one has a sequence of concave and convex longitudinal surface curvatures and the other has a sequence of convex and concave curvatures. The choice of the curvature sequences were motivated by a desire to study the asymmetric response of turbulent boundary layers to convex and concave curvatures. The relaxation of a boundary layer from the effects of these two opposite sequences has been compared. The effect of the accompaying sequences of pressure gradient has also been examined but the effect of curvature dominates. The growth of internal layers at the curvature junctions have been studied. Measurements of the Gortler and corner vortex systems have been made. The boundary layer recovering from the sequence of concave to convex curvature has a sustained lower skin friction level than in that recovering from the sequence of convex to concave curvature. The amplification and suppression of turbulence due to the curvature sequences have also been studied.
High resolution studies of complex solar active regions
NASA Astrophysics Data System (ADS)
Deng, Na
Flares and Coronal Mass Ejections (CMEs) are energetic events, which can even impact the near-Earth environment and are the principal source of space weather. Most of them originate in solar active regions. The most violent events are produced in sunspots with a complex magnetic field topology. Studying their morphology and dynamics is helpful in understanding the energy accumulation and release mechanisms for flares and CMEs, which are intriguing problems in solar physics. The study of complex active regions is based on high-resolution observations from space missions and new instruments at the Big Bear Solar Observatory (BBSO). Adaptive optics (AO) in combination with image restoration techniques (speckle masking imaging) can achieve improved image quality and a spatial resolution (about 100 km on the solar surface) close to the diffraction limit of BBSO's 65 cm vacuum telescope. Dopplergrams obtained with a two-dimensional imaging spectrometer combined with horizontal flow maps derived with Local Correlation Tracking (LCT) provide precise measurements of the three-dimensional velocity field in sunspots. Magnetic field measurements from ground- and space-based instruments complement these data. At the outset of this study, the evolution and morphology of a typical round sunspot are described in some detail. The sunspot was followed from disk center to the limb, thus providing some insight into the geometry of the magnetic flux system. Having established a benchmark for a stable sunspot, the attention is turned to changes of the sunspot structure associated with flares and CMEs. Rapid penumbral decay and the strengthening of sunspot umbrae are manifestations of photospheric magnetic field changes after a flare. These sudden intensity changes are interpreted as a result of magnetic reconnection during the flare, which causes the magnetic field lines to be turned from more inclined to more vertical. Strong photospheric shear flows along the flaring magnetic
Kinetic information from detonation front curvature
Souers, P. C., LLNL
1998-06-15
The time constants for time-dependent modeling may be estimated from reaction zone lengths, which are obtained from two sources One is detonation front curvature, where the edge lag is close to being a direct measure The other is the Size Effect, where the detonation velocity decreases with decreasing radius as energy is lost to the cylinder edge A simple theory that interlocks the two effects is given A differential equation for energy flow in the front is used, the front is described by quadratic and sixth-power radius terms The quadratic curvature comes from a constant power source of energy moving sideways to the walls Near the walls, the this energy rises to the total energy of detonation and produces the sixth-power term The presence of defects acting on a short reaction zone can eliminate the quadratic part while leaving the wall portion of the cuvature A collection of TNT data shows that the reaction zone increases with both the radius and the void fraction
Particles and curvatures in nematic liquid crystals
NASA Astrophysics Data System (ADS)
Serra, Francesca; Luo, Yimin; Yang, Shu; Kamien, Randall D.; Stebe, Kathleen J.
Elastic interactions in anisotropic fluids can be harnessed to direct particle interactions. A strategy to smoothly manipulate the director field in nematic liquid crystals is to vary the topography of the bounding surfaces. A rugged landscape with peaks and valleys create local deformations of the director field which can interact with particles in solution. We study this complex interaction in two different settings. The first consists of an array of shallow pores in a poly-dimethyl-siloxane (PDMS) membrane, whose curvature can be tuned either by swelling the PDMS membrane or by mechanical stretching. The second is a set of grooves with wavy walls, fabricated by photolithography, with various parameters of curvature and shapes. In this contexts we study how the motion of colloidal particles in nematic liquid crystals can be influenced by their interaction with the peaks and valleys of the bottom substrate or of the side walls. Particles with different associated topological defects (hedgehogs or Saturn rings) behave differently as they interact with the topographical features, favoring the docking on peaks or valleys. These experimental systems are also ideal to study the ``lock and key'' mechanism of particles in holes and to investigate a possible route for particle sorting.
Vortex motion on surfaces of small curvature
Dorigoni, Daniele Dunajski, Maciej Manton, Nicholas S.
2013-12-15
We consider a single Abelian Higgs vortex on a surface Σ whose Gaussian curvature K is small relative to the size of the vortex, and analyse vortex motion by using geodesics on the moduli space of static solutions. The moduli space is Σ with a modified metric, and we propose that this metric has a universal expansion, in terms of K and its derivatives, around the initial metric on Σ. Using an integral expression for the Kähler potential on the moduli space, we calculate the leading coefficients of this expansion numerically, and find some evidence for their universality. The expansion agrees to first order with the metric resulting from the Ricci flow starting from the initial metric on Σ, but differs at higher order. We compare the vortex motion with the motion of a point particle along geodesics of Σ. Relative to a particle geodesic, the vortex experiences an additional force, which to leading order is proportional to the gradient of K. This force is analogous to the self-force on bodies of finite size that occurs in gravitational motion. -- Highlights: •We study an Abelian Higgs vortex on a surface with small curvature. •A universal expansion for the moduli space metric is proposed. •We numerically check the universality at low orders. •Vortex motion differs from point particle motion because a vortex has a finite size. •Moduli space geometry has similarities with the geometry arising from Ricci flow.
Compact optical fiber curvature sensor based on concatenating two tapers.
Monzon-Hernandez, D; Martinez-Rios, A; Torres-Gomez, I; Salceda-Delgado, G
2011-11-15
A low-loss, compact, and highly sensitive optical fiber curvature sensor is presented. The device consists of two identical low-loss fused fiber tapers in tandem separated by a distance L. When the optical fiber is kept straight and fixed, no interference pattern appears in the transmitted spectrum. However, when the device is bent, the symmetry of the straight taper is lost and the first taper couples light into the cladding modes. In the second taper, a fraction of the total light guided by the cladding modes will be coupled back to the fundamental mode, producing an interference pattern in the transmitted spectrum. As the fiber device is bent, visibility of the interference fringes grows, reaching values close to 1. The dynamic range of the device can be tailored by the proper selection of taper diameter and separation between tapers. The effects of temperature and refractive index of the external medium on the response of the curvature sensor is also discussed. PMID:22089570
Magnetophoretic induction of curvature in coleoptiles and hypocotyls
NASA Technical Reports Server (NTRS)
Kuznetsov, O. A.; Hasenstein, K. H.
1997-01-01
Coleoptiles of barley (Hordeum vulgare) were positioned in a high gradient magnetic field (HGMF, dynamic factor gradient of H(2)/2 of 10(9)-10(10) Oe2 cm-1), generated by a ferromagnetic wedge in a uniform magnetic field and rotated on a 1 rpm clinostat. After 4 h 90% of coleoptiles had curved toward the HGMF. The cells affected by HGMF showed clear intracellular displacement of amyloplasts. Coleoptiles in a magnetic field next to a non-ferromagnetic wedge showed no preferential curvature. The small size of the area of nonuniformity of the HGMF allowed mapping of the sensitivity of the coleoptiles by varying the initial position of the wedge relative to the coleoptile apex. When the ferromagnetic wedge was placed 1 mm below the coleoptile tip only 58% of the coleoptiles curved toward the wedge indicating that the cells most sensitive to intracellular displacement of amyloplasts and thus gravity sensing are confined to the top 1 mm portion of barley coleoptiles. Similar experiments with tomato hypocotyls (Lycopersicum esculentum) also resulted in curvature toward the HGMF. The data strongly support the amyloplast-based gravity-sensing system in higher plants and the usefulness of HGMF to substitute gravity in shoots.
NASA Astrophysics Data System (ADS)
Liu, Huilian; Li, Weijun; Li, Hongbo; Sun, Yunfei; Song, Junlin; Yang, Jinghai; Gao, Ming; Liu, Xiaoyan
2015-07-01
The influence of substrate curvature on structural, optical properties of Cu, Co codoped ZnO thin films were investigated in this study. XRD analysis indicated that the crystal quality of the ZnO films could been influenced by the substrate curvature. The biaxial stress of our samples was measured by side-inclination X-ray diffraction technique. The results indicated that the type of the stress was biaxial compressive stress. Optical absorption spectra showed the absorption edge of our samples displayed blueshift with decreasing substrate curvature. Gauss fit for PL emission spectra showed that the substrate curvature affected the PL properties of the Cu, Co codoped ZnO thin films deposited on polystyrene particles. The various substrates induced defect-related emission increased in visible region.
Determination of curvature and twist of deformed object by digital holographic interferometry
NASA Astrophysics Data System (ADS)
Quan, C.; Chen, W.; Tay, C. J.
2008-11-01
This paper describes a feasibility study of digital holographic interferometry for the measurement of curvature and twist of a deformed object. Measurement of curvature and twist is an important aspect in experimental mechanics. Numerous methods have been proposed to determine the curvature and twist by using digital shearography. We proposed a novel method to determine curvature and twist based on digital holography (DH) and complex phasor (CP). In the conventional methods, phase difference between the first and second states is obtained directly by digital phase subtraction (DPS) and Fourier transform is then employed to extract phase maps. In this study, CP method is proposed to improve the quality of phase maps corresponding to second-order derivatives. Subsequently, sine/cosine transformation and short time Fourier transform (STFT) are employed to process the wrapped phase maps. An experiment is conducted on a clamped circular plate under a point load at centre. The experimental results show that the proposed method is valid and able to obtain high quality phase maps corresponding to curvature and twist of a deformed object.
Quantifying Membrane Curvature Generation of Drosophila Amphiphysin N-BAR Domains
Heinrich, Michael C.; Capraro, Benjamin R.; Tian, Aiwei; Isas, Jose M.; Langen, Ralf; Baumgart, Tobias
2012-01-01
Biological membrane functions are coupled to membrane curvature, the regulation of which often involves membrane-associated proteins. The membrane-binding N-terminal amphipathic helix-containing BIN/Amphiphysin/Rvs (N-BAR) domain of amphiphysin is implicated in curvature generation and maintenance. Improving the mechanistic understanding of membrane curvature regulation by N-BAR domains requires quantitative experimental characterization. We have measured tube pulling force modulation by the N-BAR domain of Drosophila amphiphysin (DA-N-BAR) bound to tubular membranes pulled from micropipette-aspirated giant vesicles. We observed that fluorescently-labeled DA-N-BAR showed significantly higher protein density on tubules compared to the connected low-curvature vesicle membrane. Furthermore, we found the equilibrium tube pulling force to be systematically dependent on the aqueous solution concentration of DA-N-BAR, thereby providing the first quantitative assessment of spontaneous curvature generation. At sufficiently high protein concentrations, pulled tubes required no external force to maintain mechanical equilibrium, in agreement with the qualitative spontaneous tubulation previously reported for amphiphysin. PMID:23772271
Detection of zones of abnormal strains in structures using Gaussian curvature analysis
Lisle, R.J.
1994-12-01
Whereas some folds, such as those produced by flexural slip, do not theoretically entail strain within the folded surfaces, any surface involving double curvature (such as domes and saddles) cannot form without some stretching or contraction of the bedding. Whether straining of the surfaces is required during folding depends on the three-dimensional fold shape and, in particular, on the Gaussian curvature at points on the folded surface. Using this as a basis, I present a method for detecting zones of anomalously high strain in oil-field structures from Gaussian curvature analysis (GCA) of natural structures. The new method of GCA is suitable for analyzing surfaces that have been mapped seismically. A Gaussian curvature map of the structure is a principal outcome of the analysis and can be used to predict the density of strain-related subseismic structures, such as small-scale fracturing. The Goose Egg dome, near Casper, Wyoming, is analyzed and provides an example of GCA. In this structure, a relationship is observed between fracture densities and Gaussian curvature.
Multi-scale curvature for automated identification of glaciated mountain landscapes☆
Prasicek, Günther; Otto, Jan-Christoph; Montgomery, David R.; Schrott, Lothar
2014-01-01
Erosion by glacial and fluvial processes shapes mountain landscapes in a long-recognized and characteristic way. Upland valleys incised by fluvial processes typically have a V-shaped cross-section with uniform and moderately steep slopes, whereas glacial valleys tend to have a U-shaped profile with a changing slope gradient. We present a novel regional approach to automatically differentiate between fluvial and glacial mountain landscapes based on the relation of multi-scale curvature and drainage area. Sample catchments are delineated and multiple moving window sizes are used to calculate per-cell curvature over a variety of scales ranging from the vicinity of the flow path at the valley bottom to catchment sections fully including valley sides. Single-scale curvature can take similar values for glaciated and non-glaciated catchments but a comparison of multi-scale curvature leads to different results according to the typical cross-sectional shapes. To adapt these differences for automated classification of mountain landscapes into areas with V- and U-shaped valleys, curvature values are correlated with drainage area and a new and simple morphometric parameter, the Difference of Minimum Curvature (DMC), is developed. At three study sites in the western United States the DMC thresholds determined from catchment analysis are used to automatically identify 5 × 5 km quadrats of glaciated and non-glaciated landscapes and the distinctions are validated by field-based geological and geomorphological maps. Our results demonstrate that DMC is a good predictor of glacial imprint, allowing automated delineation of glacially and fluvially incised mountain landscapes. PMID:24748703
Multi-scale curvature for automated identification of glaciated mountain landscapes.
Prasicek, Günther; Otto, Jan-Christoph; Montgomery, David R; Schrott, Lothar
2014-03-15
Erosion by glacial and fluvial processes shapes mountain landscapes in a long-recognized and characteristic way. Upland valleys incised by fluvial processes typically have a V-shaped cross-section with uniform and moderately steep slopes, whereas glacial valleys tend to have a U-shaped profile with a changing slope gradient. We present a novel regional approach to automatically differentiate between fluvial and glacial mountain landscapes based on the relation of multi-scale curvature and drainage area. Sample catchments are delineated and multiple moving window sizes are used to calculate per-cell curvature over a variety of scales ranging from the vicinity of the flow path at the valley bottom to catchment sections fully including valley sides. Single-scale curvature can take similar values for glaciated and non-glaciated catchments but a comparison of multi-scale curvature leads to different results according to the typical cross-sectional shapes. To adapt these differences for automated classification of mountain landscapes into areas with V- and U-shaped valleys, curvature values are correlated with drainage area and a new and simple morphometric parameter, the Difference of Minimum Curvature (DMC), is developed. At three study sites in the western United States the DMC thresholds determined from catchment analysis are used to automatically identify 5 × 5 km quadrats of glaciated and non-glaciated landscapes and the distinctions are validated by field-based geological and geomorphological maps. Our results demonstrate that DMC is a good predictor of glacial imprint, allowing automated delineation of glacially and fluvially incised mountain landscapes. PMID:24748703
Compact surfaces of constant Gaussian curvature in Randers manifolds
NASA Astrophysics Data System (ADS)
Cui, Ningwei
2016-08-01
The flag curvature of a Finsler surface is called the Gaussian curvature in Finsler geometry. In this paper, we characterize the surfaces of constant Gaussian curvature (CGC) in the Randers 3-manifold. Then we give a classification of the orientable closed CGC surfaces in two Randers space forms, which are the non-Euclidean Minkowski-Randers 3-space (K = 0) and the Bao-Shen sphere (K = 1).
Eddy-Current Measurement Of Turning Or Curvature
NASA Technical Reports Server (NTRS)
Chern, Engmin J.
1993-01-01
Rotatable conductive plate covers sensing coil to varying degree. Curvature of pipe at remote or otherwise inaccessible location inside pipe measured using relatively simple angular-displacement eddy-current probe. Crawler and sensor assemblies move along inside of pipe on wheels. Conductive plate pivots to follow curvature of pipe, partly covering one of eddy-current coils to degree depending on local curvature on pipe.
Wrinkles and splay conspire to give positive disclinations negative curvature.
Matsumoto, Elisabetta A; Vega, Daniel A; Pezzutti, Aldo D; García, Nicolás A; Chaikin, Paul M; Register, Richard A
2015-10-13
Recently, there has been renewed interest in the coupling between geometry and topological defects in crystalline and striped systems. Standard lore dictates that positive disclinations are associated with positive Gaussian curvature, whereas negative disclinations give rise to negative curvature. Here, we present a diblock copolymer system exhibiting a striped columnar phase that preferentially forms wrinkles perpendicular to the underlying stripes. In free-standing films this wrinkling behavior induces negative Gaussian curvature to form in the vicinity of positive disclinations. PMID:26420873
Wrinkles and splay conspire to give positive disclinations negative curvature
Matsumoto, Elisabetta A.; Vega, Daniel A.; Pezzutti, Aldo D.; García, Nicolás A.; Chaikin, Paul M.; Register, Richard A.
2015-01-01
Recently, there has been renewed interest in the coupling between geometry and topological defects in crystalline and striped systems. Standard lore dictates that positive disclinations are associated with positive Gaussian curvature, whereas negative disclinations give rise to negative curvature. Here, we present a diblock copolymer system exhibiting a striped columnar phase that preferentially forms wrinkles perpendicular to the underlying stripes. In free-standing films this wrinkling behavior induces negative Gaussian curvature to form in the vicinity of positive disclinations. PMID:26420873
Blood, Philip D.; Swenson, Richard D.; Voth, Gregory A.
2008-01-01
N-BAR domains are protein modules that bind to and induce curvature in membranes via a charged concave surface and N-terminal amphipathic helices. Recently, molecular dynamics simulations have demonstrated that the N-BAR domain can induce a strong local curvature that matches the curvature of the BAR domain surface facing the bilayer. Here we present further molecular dynamics simulations that examine in greater detail the roles of the concave surface and amphipathic helices in driving local membrane curvature. We find that the strong curvature induction observed in our previous simulations requires the stable presentation of the charged concave surface to the membrane and is not driven by the membrane-embedded amphipathic helices. Nevertheless, without these amphipathic helices embedded in the membrane, the N-BAR domain does not maintain a close association with the bilayer, and fails to drive membrane curvature. Increasing the membrane negative charge through the addition of PIP2 facilitates closer association with the membrane in the absence of embedded helices. At sufficiently high concentrations, amphipathic helices embedded in the membrane drive membrane curvature independently of the BAR domain. PMID:18469070
Borges, Mauricia Ferreira de Almeida E; Miranda, Carlos Eduardo Saraiva; Silva, Silvio Rocha Corrêa da; Marchesan, Melissa
2011-01-01
Optical microscopy and morphometric analysis were used in this study to evaluate, in vitro, the cleaning of the apical region in root canals with mild or moderate curvatures subjected to biomechanical preparation with a rotary system, as well as to assess the amount of extruded material to the periapical area. Lateral incisors (n = 32), 16 with curvature angles smaller or equal to 10º (GI) and 16 between 11º and 25º angles (GII) were submitted to Hero 642 rotary instrumentation with different surgical diameters: (A) 30.02 and (B) 45.02. Irrigation was performed at each change of instrument with 5 mL of ultrapure Milli-Q water and the extruded material through the apical foramen was collected. Root cross-sections were subjected to histological analysis by optical microscopy (×40) and the images were evaluated morphometrically using the Image Tool software. Quantification of the extruded material was performed by weighing after liquid evaporation. ANOVA showed no statistically significant differences (p>0.05) among the groups with respect to the procedures used to clean the apical region. Considering the amount of extruded material, the Tukey's HSD showed that canals with mild curvature prepared with the 45.02 surgical diameter showed significantly higher values (p<0.05) that those of the other groups, which were similar between themselves (p>0.05). In conclusion, the effect of cleaning the apical region did not differ in the groups, considering root curvature and the surgical diameter of instruments used for apical preparation. The amount of extruded material was greater in canals with mild curvature that were prepared with the 45.02 surgical instrument diameter. PMID:21915518
Evolution of the curvature perturbations during warm inflation
Matsuda, Tomohiro
2009-06-15
This paper considers warm inflation as an interesting application of multi-field inflation. Delta-N formalism is used for the calculation of the evolution of the curvature perturbations during warm inflation. Although the perturbations considered in this paper are decaying after the horizon exit, the corrections to the curvature perturbations sourced by these perturbations can remain and dominate the curvature perturbations at large scales. In addition to the typical evolution of the curvature perturbations, inhomogeneous diffusion rate is considered for warm inflation, which may lead to significant non-Gaussianity of the spectrum.
Mean Curvature Flow in a Ricci Flow Background
NASA Astrophysics Data System (ADS)
Lott, John
2012-07-01
Following work of Ecker (Comm Anal Geom 15:1025-1061, 2007), we consider a weighted Gibbons-Hawking-York functional on a Riemannian manifold-with-boundary. We compute its variational properties and its time derivative under Perelman's modified Ricci flow. The answer has a boundary term which involves an extension of Hamilton's differential Harnack expression for the mean curvature flow in Euclidean space. We also derive the evolution equations for the second fundamental form and the mean curvature, under a mean curvature flow in a Ricci flow background. In the case of a gradient Ricci soliton background, we discuss mean curvature solitons and Huisken monotonicity.
Plane wave gravitons, curvature singularities and string physics
Brooks, R. . Center for Theoretical Physics)
1991-03-21
This paper discusses bounded (compactifying) potentials arising from a conspiracy between plane wave graviton and dilaton condensates. So are string propagation and supersymmetry in spacetimes with curvature singularities.
Vectorial detection of sub-microscale capillary curvature by laser beam profile
NASA Astrophysics Data System (ADS)
Verma, Gopal; Singh, Kamal P.
2015-10-01
We demonstrate a simple and non-invasive optical technique to detect direction and magnitude of long-range, sub-microscale capillary curvature of fluid interfaces in various situations. By analyzing magnitude and direction of the distorted spatial profile of the laser beam, following its weak Fresnel's reflection from the air-water interface, ultra-low curvature of 0.1 μm-1 caused by dipped slides, glass tubes, and microscopic twisted silk fibers was measured up to six capillary lengths away from the object. The flexibility of this technique allows us to measure curvature of remotely placed fluid-fluid interfaces and interaction between capillary curves of multiple objects. The high sensitivity of our technique is demonstrated in measuring magnetic susceptibility of water and the full spatial profile of deformation under weak magnetic field. This technique might find applications in precision measurements in optofluidics and interface physics.
Induction of Plant Curvature by Magnetophoresis and Cytoskeletal Changes during Root Graviresponse
NASA Technical Reports Server (NTRS)
Hasenstein, Karl H.; Kuznetsov, Oleg A.; Blancaflor, Eilson B.
1996-01-01
High gradient magnetic fields (HGMF) induce curvature in roots and shoots. It is considered that this response is likely to be based on the intracellular displacement of bulk starch (amyloplasts) by the ponderomotive force generated by the HGMF. This process is called magnetophoresis. The differential elongation during the curvature along the concave and convex flanks of growing organs may be linked to the microtubular and/or microfilament cytoskeleton. The possible existence of an effect of the HGMF on the cytoskeleton was tested for, but none was found. The application of cytoskeletal stabilizers or depolymerizers showed that neither microtubules, nor microfilaments, are involved in the graviresponse.
Nonminimal coupling of perfect fluids to curvature
Bertolami, Orfeu; Lobo, Francisco S. N.; Paramos, Jorge
2008-09-15
In this work, we consider different forms of relativistic perfect fluid Lagrangian densities that yield the same gravitational field equations in general relativity (GR). A particularly intriguing example is the case with couplings of the form [1+f{sub 2}(R)]L{sub m}, where R is the scalar curvature, which induces an extra force that depends on the form of the Lagrangian density. It has been found that, considering the Lagrangian density L{sub m}=p, where p is the pressure, the extra-force vanishes. We argue that this is not the unique choice for the matter Lagrangian density, and that more natural forms for L{sub m} do not imply the vanishing of the extra force. Particular attention is paid to the impact on the classical equivalence between different Lagrangian descriptions of a perfect fluid.
Natural curvature for manifest T-duality
NASA Astrophysics Data System (ADS)
Poláček, Martin; Siegel, Warren
2014-01-01
We reformulate the manifestly T-dual description of the massless sector of the closed bosonic string, directly from the geometry associated with the (left and right) affine Lie algebra of the coset space Poincaré/Lorentz. This construction initially doubles not only the (spacetime) coordinates for translations but also those for Lorentz transformations (and their "dual"). As a result, the Lorentz connection couples directly to the string (as does the vielbein), rather than being introduced ad hoc to the covariant derivative as previously. This not only reproduces the old definition of T-dual torsion, but automatically gives a general, covariant definition of T-dual curvature (but still with some undetermined connections).
Hawking temperature of constant curvature black holes
Cai Ronggen; Myung, Yun Soo
2011-05-15
The constant curvature (CC) black holes are higher dimensional generalizations of Banados-Teitelboim-Zanelli black holes. It is known that these black holes have the unusual topology of M{sub D-1}xS{sup 1}, where D is the spacetime dimension and M{sub D-1} stands for a conformal Minkowski spacetime in D-1 dimensions. The unusual topology and time-dependence for the exterior of these black holes cause some difficulties to derive their thermodynamic quantities. In this work, by using a globally embedding approach, we obtain the Hawking temperature of the CC black holes. We find that the Hawking temperature takes the same form when using both the static and global coordinates. Also, it is identical to the Gibbons-Hawking temperature of the boundary de Sitter spaces of these CC black holes.
NASA Astrophysics Data System (ADS)
Diaz, Jordi; Gallart, Josep
2014-05-01
The knowledge of the anisotropic properties beneath the Iberian Peninsula and Northern Morocco has been dramatically changed since late 2007 with the analysis of the data provided by the dense TopoIberia-Iberarray broad-band seismic network, the increasing number of permanent stations operating in Morocco, Portugal and Spain and the contribution of smaller scale/higher resolution experiments. The first TopoIberia deployment in the Betics-Alboran zone has evidenced a spectacular rotation of the fast polarization direction (FPD) along the Gibraltar arc following the curvature of the Rif-Betic chain, from roughly N65E beneath the Betics to close to N65W beneath the Rif chain. (Díaz et al, 2010). This result, confirmed latter on by the analysis of the PICASSO experiment data (Miller et al., 2013), has been interpreted as an evidence of mantle flow deflected around the high velocity slab identified by tomographic methods beneath the Gibraltar Arc. Data from the second TopoIberia deployment and from additional deployments in the Moroccan Meseta and the western High Atlas, allowed expanding the investigated area and obtaining a larger scale image of the mantle flow around the region. Diaz et al. (2014) have shown that SW Portugal and the western High Atlas regions have a small degree of anisotropy and a large number of "null" measurements, which suggest the presence of vertical flow in the mantle associated to small-scale edge-driven convective cells. The rather uniform N100ºE FPD retrieved beneath the Variscan Central Iberian Massif is consistent with global mantle flow models taking into account contributions of surface plate motion, density variations and net lithosphere rotation. The last Iberarray deployment covers the northern part of the Iberian Peninsula and has been coeval with the deployment of a similar seismic network in southern France in the framework of the Pyrope project. Even if data from short term experiments in the Pyrenees and northern Iberia have
Local curvature measurements of a lean, partially premixed swirl-stabilised flame
NASA Astrophysics Data System (ADS)
Bayley, Alan E.; Hardalupas, Yannis; Taylor, Alex M. K. P.
2012-04-01
A swirl-stabilised, lean, partially premixed combustor operating at atmospheric conditions has been used to investigate the local curvature distributions in lifted, stable and thermoacoustically oscillating CH4-air partially premixed flames for bulk cold-flow Reynolds numbers of 15,000 and 23,000. Single-shot OH planar laser-induced fluorescence has been used to capture instantaneous images of these three different flame types. Use of binary thresholding to identify the reactant and product regions in the OH planar laser-induced fluorescence images, in order to extract accurate flame-front locations, is shown to be unsatisfactory for the examined flames. The Canny-Deriche edge detection filter has also been examined and is seen to still leave an unacceptable quantity of artificial flame-fronts. A novel approach has been developed for image analysis where a combination of a non-linear diffusion filter, Sobel gradient and threshold-based curve elimination routines have been used to extract traces of the flame-front to obtain local curvature distributions. A visual comparison of the effectiveness of flame-front identification is made between the novel approach, the threshold binarisation filter and the Canny-Deriche filter. The novel approach appears to most accurately identify the flame-fronts. Example histograms of the curvature for six flame conditions and of the total image area are presented and are found to have a broader range of local flame curvatures for increasing bulk Reynolds numbers. Significantly positive values of mean curvature and marginally positive values of skewness of the histogram have been measured for one lifted flame case, but this is generally accounted for by the effect of flame brush curvature. The mean local flame-front curvature reduces with increasing axial distance from the burner exit plane for all flame types. These changes are more pronounced in the lifted flames but are marginal for the thermoacoustically oscillating flames. It is
NASA Technical Reports Server (NTRS)
Cosgrove, D. J.
1990-01-01
The growth response of etiolated cucumber (Cucumis sativus L.) hypocotyls to gravitropic stimulation was examined by means of time-lapse photography and high-resolution analysis of surface expansion and curvature. In comparison with video analysis, the technique described here has five- to 20-fold better resolution; moreover, the mathematical fitting method (cubic splines) allows direct estimation of local and integrated curvature. After switching seedlings from a vertical to horizontal position, both upper and lower surfaces of the stem reacted after a lag of about 11 min with a two- to three-fold increase in surface expansion rate on the lower side and a cessation of expansion, or slight compression, on the upper surface. This growth asymmetry was initiated simultaneously along the length of the hypocotyl, on both upper and lower surfaces, and did not migrate basipetally from the apex. Later stages in the gravitropic response involved a complex reversal of the growth asymmetry, with the net result being a basipetal migration of the curved region. This secondary growth reversal may reflect oscillatory and/or self-regulatory behaviour of growing cells. With some qualifications, the kinetics and pattern of growth response are consistent with a mechanism involving hormone redistribution, although they do not prove such a mechanism. The growth kinetics require a growth mechanism which can be stimulated by two- to three-fold or completely inhibited within a few minutes.
Relic HII regions and radiative feedback at high redshifts
NASA Astrophysics Data System (ADS)
Mesinger, Andrei; Bryan, Greg L.; Haiman, Zoltán
2009-11-01
Ultraviolet (UV) radiation from early astrophysical sources could have a large impact on subsequent star formation in nearby protogalaxies, and in general on the progress of cosmological reionization. Theoretical arguments based on the absence of metals in the early Universe suggest that the first stars were likely massive, bright, yet short-lived, with lifetimes of a few million years. Here we study the radiative feedback arising from such stars using hydrodynamical simulations with transient UV backgrounds (UVBs) and persistent Lyman-Werner backgrounds (LWBs) of varying intensity. We extend our prior work in Mesinger et al., by studying a more typical region whose protogalaxies form at lower redshifts, z ~ 13-20, in the epoch likely preceding the bulk of reionization. We confirm our previous results that feedback in the relic HII regions resulting from such transient radiation is itself transient. Feedback effects dwindle away after ~30 per cent of the Hubble time, and the same critical specific intensity of JUV ~ 0.1 × 10-21ergs-1cm-2Hz-1sr-1 separates positive and negative feedback regimes. This suggests that overall feedback is fairly insensitive to the large-scale environment, overdensity and redshift-dependent halo parameters, and can accurately be modelled in this regime with just the intensity of the impinging UVB. Additionally, we discover a second episode of eventual positive feedback in haloes which have not yet collapsed when their progenitor regions were exposed to the transient UVB. When exposed to the transient UVB, this gas suffers relatively little density depletion but a significant enhancement of the molecular hydrogen abundance, thus resulting in net positive feedback. This eventual positive feedback appears in all runs, regardless of the strength of the UVB. However, this feedback regime is very sensitive to the presence of Lyman-Werner radiation, and notable effects disappear under fairly modest background intensities of JLW >~ 10-3 × 10
Measurement of the Earth's Radius Based on Historical Evidence of Its Curvature
ERIC Educational Resources Information Center
Roura, Pere; Josep, Calbo
2005-01-01
Probably the most direct observation of the Earth's curvature is how objects appear from over the horizon when we approach them and disappear as we get further away from them. Similarly, the portion of a high object (a building or a mountain) that is visible depends on the height of the site where the observation is made. Based upon these very…
Curvature and anisotropy estimation through the CRS approximation
NASA Astrophysics Data System (ADS)
Xu, Shibo; Stovas, Alexey
2015-12-01
Multiparameter stacking is a crucial tool to get a high-quality time image of the subsurface, which can provide a basis for many important applications. We analyse the CRS approximation for a circular reflector embedded into effective anisotropic media. In this case, the CRS attributes depend on both reflector curvature and anisotropy parameters. We consider the effective anisotropic model from two anisotropic cases—elliptical isotropic and transversely isotropic with vertical symmetry axis—and one vertically heterogeneous isotropic case, i.e. two-layer model. By performing a sensitivity analysis, we show how the estimates depend on anisotropy parameters. We convert the CRS attributes into parameters for the isotropic model and analyse these estimates’ behaviour along the seismic line. From this behaviour, we estimate both structure and anisotropy parameters.
Topological implications of negative curvature for biological and social networks
NASA Astrophysics Data System (ADS)
Albert, Réka; DasGupta, Bhaskar; Mobasheri, Nasim
2014-03-01
Network measures that reflect the most salient properties of complex large-scale networks are in high demand in the network research community. In this paper we adapt a combinatorial measure of negative curvature (also called hyperbolicity) to parametrized finite networks, and show that a variety of biological and social networks are hyperbolic. This hyperbolicity property has strong implications on the higher-order connectivity and other topological properties of these networks. Specifically, we derive and prove bounds on the distance among shortest or approximately shortest paths in hyperbolic networks. We describe two implications of these bounds to crosstalk in biological networks, and to the existence of central, influential neighborhoods in both biological and social networks.
Chaotic mixing in a helix-like pipe with periodic variations in curvature and torsion
NASA Astrophysics Data System (ADS)
Jang, Bongkyun; Funakoshi, Mitsuaki
2010-06-01
Chaotic motion of fluid particles due to a steady viscous flow in a helix-like circular pipe caused by an axial pressure gradient, and the mixing efficiency of this flow are numerically examined here. The pipe is wound around a circular or elliptic cylinder with a constant pitch so that the curvature κ and torsion τ of the centerline of this pipe vary continuously and periodically. If both κ and τ are small and slowly varying, the cross-sectional motion of fluid particles is expected to be approximately governed by the sum of Dean's flow and the flow of rigid rotation. From Poincaré sections and the values of an index of the extent of mixing, it is found that there is an intermediate range of Reynolds number Re of flow within which chaotic regions in Poincaré sections are large and mixing efficiency over a short time is high. Moreover, larger chaotic regions and higher mixing efficiency are observed for pipes wound around a circular cylinder of smaller radius and for pipes wound around a thinner elliptic cylinder. These results can be explained by the variation in characteristic ratio λ=12τ/(κRe) in one period.
High fertility regions in Bangladesh: a marriage cohort analysis.
Islam, Sabina; Islam, Mohammad Amirul; Padmadas, Sabu S
2010-11-01
Bangladesh represents one of the few countries in south Asia where the pace of fertility decline has been unprecedented over the last three decades. Although there has been significant reduction in fertility levels at the national level, regional variations continue to persist, especially in Sylhet and Chittagong where the total fertility rates are well above the country average. Using data from three consecutive Bangladesh Demographic and Health Surveys (BDHSs) this paper assesses how fertility patterns in Sylhet and Chittagong differ from the rest of Bangladesh through a marriage cohort analysis of the parity progression ratios, and examines the factors determining the transition rates to higher parity in these two regions. Three cohorts of women are identified: those married during 1965-1974, 1975-84 and 1985-94. The results show that the probability that a woman from the recent cohort in Sylhet or Chittagong who had a third birth will have a fourth birth is nearly twice that of her counterpart in other regions. Social characteristics such as education, occupation, religion and residence have no effect on fertility in Sylhet and Chittagong. Additional period-specific analyses using the 2007 BDHS data show that women in Sylhet are considerably more likely to have a third or fourth birth sooner than those in other divisions, especially Khulna. The findings call for specific family planning policy interventions in Sylhet and Chittagong ensuring gender equity, promoting female education and delaying entry into marriage and childbearing. PMID:20868540
Coherent gradient sensing method and system for measuring surface curvature
NASA Technical Reports Server (NTRS)
Rosakis, Ares J. (Inventor); Singh, Ramen P. (Inventor); Kolawa, Elizabeth (Inventor); Moore, Jr., Nicholas R. (Inventor)
2000-01-01
A system and method for determining a curvature of a specularly reflective surface based on optical interference. Two optical gratings are used to produce a spatial displacement in an interference field of two different diffraction components produced by one grating from different diffraction components produced by another grating. Thus, the curvature of the surface can be determined.
Effects of curvature on asymmetric steady states in catalyst particles
Lucier, B J
1981-02-01
The effects of curvature on steady states of chemical catalytic reactions are investigated by studying the cases of the catalytic particle being a spherical or cylindrical shell. Existence and stability of solutions are studied. It is shown that the solutions converge to the solutions for the catalytic slab when the curvature goes to 0 in each case.
An analytical approach to estimate curvature effect of coseismic deformations
NASA Astrophysics Data System (ADS)
Dong, Jie; Sun, Wenke; Zhou, Xin; Wang, Rongjiang
2016-06-01
We present an analytical approach to compute the curvature effect by the new analytical solutions of co-seismic deformation derived for the homogeneous sphere model. We consider two spheres with different radii: one is the same as earth, the other with a larger radius can approximate a half-space model. Then, we calculate the co-seismic displacements for the two spheres and define the relative percentage of the displacements as the curvature effect. The near-field curvature effect is defined relative to the maximum co-seismic displacement. The results show that the maximum curvature effect is about 4% for source depths of less than 100 km, and about 30% for source depths of less than 600 km. For the far-field curvature effect, we define it relative to the observing point. The curvature effect is extremely large and sometimes exceeds 100%. Moreover, this new approach can be used to estimate any planet's curvature effect quantitatively. For a smaller sphere, such as the Moon, the curvature effect is much larger than that of the Earth, with an inverse ratio to the earth's radius.
Determination of Radius of Curvature for Teeth With Cycloid Profile
NASA Astrophysics Data System (ADS)
Shatalov, E. V.; Efremenkov, E. A.; Shibinskiy, K. G.
2016-04-01
In the article the geometric determination of curvature radius is considered for teeth with cycloid profile. The equations are obtained for the determination of a radius of curvature with point coordinates of a cycloid profile. The conditions of convexo-concavity of a teeth profile are defined for transmission with intermediate rollers.
An analytical approach to estimate curvature effect of coseismic deformations
NASA Astrophysics Data System (ADS)
Dong, Jie; Sun, Wenke; Zhou, Xin; Wang, Rongjiang
2016-08-01
We present an analytical approach to compute the curvature effect by the new analytical solutions of coseismic deformation derived for the homogeneous sphere model. We consider two spheres with different radii: one is the same as earth and the other with a larger radius can approximate a half-space model. Then, we calculate the coseismic displacements for the two spheres and define the relative percentage of the displacements as the curvature effect. The near-field curvature effect is defined relative to the maximum coseismic displacement. The results show that the maximum curvature effect is about 4 per cent for source depths of less than 100 km, and about 30 per cent for source depths of less than 600 km. For the far-field curvature effect, we define it relative to the observing point. The curvature effect is extremely large and sometimes exceeds 100 per cent. Moreover, this new approach can be used to estimate any planet's curvature effect quantitatively. For a smaller sphere, such as the Moon, the curvature effect is much larger than that of the Earth, with an inverse ratio to the earth's radius.
NASA Astrophysics Data System (ADS)
Prasad, M. N.; Brown, M. S.; Ahmad, S.; Abtin, F.; Allen, J.; da Costa, I.; Kim, H. J.; McNitt-Gray, M. F.; Goldin, J. G.
2008-03-01
Segmentation of lungs in the setting of scleroderma is a major challenge in medical image analysis. Threshold based techniques tend to leave out lung regions that have increased attenuation, for example in the presence of interstitial lung disease or in noisy low dose CT scans. The purpose of this work is to perform segmentation of the lungs using a technique that selects an optimal threshold for a given scleroderma patient by comparing the curvature of the lung boundary to that of the ribs. Our approach is based on adaptive thresholding and it tries to exploit the fact that the curvature of the ribs and the curvature of the lung boundary are closely matched. At first, the ribs are segmented and a polynomial is used to represent the ribs' curvature. A threshold value to segment the lungs is selected iteratively such that the deviation of the lung boundary from the polynomial is minimized. A Naive Bayes classifier is used to build the model for selection of the best fitting lung boundary. The performance of the new technique was compared against a standard approach using a simple fixed threshold of -400HU followed by regiongrowing. The two techniques were evaluated against manual reference segmentations using a volumetric overlap fraction (VOF) and the adaptive threshold technique was found to be significantly better than the fixed threshold technique.
Molecular Modeling of Lipid Membrane Curvature Induction by a Peptide: More than Simply Shape
Sodt, Alexander J.; Pastor, Richard W.
2014-01-01
Molecular dynamics simulations of an amphipathic helix embedded in a lipid bilayer indicate that it will induce substantial positive curvature (e.g., a tube of diameter 20 nm at 16% surface coverage). The induction is twice that of a continuum model prediction that only considers the shape of the inclusion. The discrepancy is explained in terms of the additional presence of specific interactions described only by the molecular model. The conclusion that molecular shape alone is insufficient to quantitatively model curvature is supported by contrasting molecular and continuum models of lipids with large and small headgroups (choline and ethanolamine, respectively), and of the removal of a lipid tail (modeling a lyso-lipid). For the molecular model, curvature propensity is analyzed by computing the derivative of the free energy with respect to bending. The continuum model predicts that the inclusion will soften the bilayer near the headgroup region, an effect that may weaken curvature induction. The all-atom predictions are consistent with experimental observations of the degree of tubulation by amphipathic helices and variation of the free energy of binding to liposomes. PMID:24806928
A mesh-decoupled height function method for computing interface curvature
NASA Astrophysics Data System (ADS)
Owkes, Mark; Desjardins, Olivier
2015-01-01
In this paper, a mesh-decoupled height function method is proposed and tested. The method is based on computing height functions within columns that are not aligned with the underlying mesh and have variable dimensions. Because they are decoupled from the computational mesh, the columns can be aligned with the interface normal vector, which is found to improve the curvature calculation for under-resolved interfaces where the standard height function method often fails. A computational geometry toolbox is used to compute the heights in the complex geometry that is formed at the intersection of the computational mesh and the columns. The toolbox reduces the complexity of the problem to a series of straightforward geometric operations using simplices. The proposed scheme is shown to compute more accurate curvatures than the standard height function method on coarse meshes. A combined method that uses the standard height function where it is well defined and the proposed scheme in under-resolved regions is tested. This approach achieves accurate and robust curvatures for under-resolved interface features and second-order converging curvatures for well-resolved interfaces.
Effects of Iris Surface Curvature on Iris Recognition
Thompson, Joseph T; Flynn, Patrick J; Bowyer, Kevin W; Santos-Villalobos, Hector J
2013-01-01
To focus on objects at various distances, the lens of the eye must change shape to adjust its refractive power. This change in lens shape causes a change in the shape of the iris surface which can be measured by examining the curvature of the iris. This work isolates the variable of iris curvature in the recognition process and shows that differences in iris curvature degrade matching ability. To our knowledge, no other work has examined the effects of varying iris curvature on matching ability. To examine this degradation, we conduct a matching experiment across pairs of images with varying degrees of iris curvature differences. The results show a statistically signi cant degradation in matching ability. Finally, the real world impact of these ndings is discussed
Nastic curvatures of wheat coleoptiles that develop in true microgravity
NASA Technical Reports Server (NTRS)
Heathcote, D. G.; Chapman, D. K.; Brown, A. H.
1995-01-01
Dark-grown wheat coleoptiles developed strong curvatures within 5 h of being transferred in orbit from a 1 g centrifuge to microgravity during an experiment flown on the IML-1 shuttle mission. The curving tendency was strongest in seedlings that were immature, with coleoptiles shorter than 10 mm at the time of transfer. The curvature direction was non-random, and directed away from the caryopsis (the coleptile face adjacent to the caryopsis becoming convex). The curvatures were most marked in the basal third of the coleoptiles, contrasting with phototropic responses, which occur in the apical third. We interpret these curvatures as being nastic, and related to the curvatures commonly reported to occur during clinostat rotation treatments.
Elliptic inflation: generating the curvature perturbation without slow-roll
NASA Astrophysics Data System (ADS)
Matsuda, Tomohiro
2006-09-01
There are many inflationary models in which the inflaton field does not satisfy the slow-roll condition. However, in such models, it is always difficult to generate the curvature perturbation during inflation. Thus, to generate the curvature perturbation, one must introduce another component into the theory. To cite a case, curvatons may generate the dominant part of the curvature perturbation after inflation. However, we question whether it is realistic to consider the generation of the curvature perturbation during inflation without slow-roll. Assuming multifield inflation, we encounter the generation of curvature perturbation during inflation without slow-roll. The potential along the equipotential surface is flat by definition and thus we do not have to worry about symmetry. We also discuss KKLT (Kachru Kallosh Linde Trivedi) models, in which corrections lifting the inflationary direction may not become a serious problem if there is a symmetry enhancement at the tip (not at the moving brane) of the inflationary throat.
Robust pupil center detection using a curvature algorithm
NASA Technical Reports Server (NTRS)
Zhu, D.; Moore, S. T.; Raphan, T.; Wall, C. C. (Principal Investigator)
1999-01-01
Determining the pupil center is fundamental for calculating eye orientation in video-based systems. Existing techniques are error prone and not robust because eyelids, eyelashes, corneal reflections or shadows in many instances occlude the pupil. We have developed a new algorithm which utilizes curvature characteristics of the pupil boundary to eliminate these artifacts. Pupil center is computed based solely on points related to the pupil boundary. For each boundary point, a curvature value is computed. Occlusion of the boundary induces characteristic peaks in the curvature function. Curvature values for normal pupil sizes were determined and a threshold was found which together with heuristics discriminated normal from abnormal curvature. Remaining boundary points were fit with an ellipse using a least squares error criterion. The center of the ellipse is an estimate of the pupil center. This technique is robust and accurately estimates pupil center with less than 40% of the pupil boundary points visible.
Transient erosion rates predicted from topographic curvature of ridges (Feather River, California)
NASA Astrophysics Data System (ADS)
Hurst, M. D.; Mudd, S. M.; Walcott, R.; Yoo, K.; Attal, M.
2010-12-01
Rates of erosion can control the morphology of entire landscapes. Methods to quantify erosion are expensive and time consuming, but potentially these rates may be predicted rapidly over large spatial extents using topographic metrics. In landscapes with similar vegetation, climate and geology, mean basin slope has been shown to be linearly correlated with erosion rate, except in rapidly eroding landscapes where hillslopes steepen to approach a threshold slope. However landscape evolution models in which hillslope sediment flux is non-linearly dependent on slopes predict the curvature of ridges to be linearly proportional to erosion rates (Roering et al 2007). The curvature of hilltops may respond to higher erosion rates than mean basin slope as ridge curvature is only limited by whether soil production can keep pace with channel erosion rates. We test the utility of ridge-top curvature for estimating erosion rates using high resolution (1m) Airborne Laser Swath Mapping (ALSM) derived digital elevation data. Cosmogenic radionuclide (CRN) derived erosion rates for our field site in the Feather River, California, suggests erosion rates vary over an order of magnitude (0.01 to >0.2cm yr-1) (Riebe et al 2000). These data, combined with new CRN-derived erosion rates, are used to demonstrate erosion scales linearly with hilltop curvature, where hillslopes are judged to have adjusted to the erosion rate in the channel at their toe. From this relationship we determine the diffusion coefficient which controls the relationship between hillslope gradient and sediment flux, allowing estimation of erosion rates throughout our field area. Previous workers have demonstrated that mean hillslope angle can stand as a proxy for erosion rates only at rates <~0.25mm yr-1, until threshold angles are reached (e.g. Binnie et al 2007). Using an algorithm to extract a network of ridgelines and sample the mean hilltop curvature for a series of drainage basins in the study area, we show that
Rapid pedobarographic image registration based on contour curvature and optimization.
Oliveira, Francisco P M; Tavares, João Manuel R S; Pataky, Todd C
2009-11-13
Image registration, the process of optimally aligning homologous structures in multiple images, has recently been demonstrated to support automated pixel-level analysis of pedobarographic images and, subsequently, to extract unique and biomechanically relevant information from plantar pressure data. Recent registration methods have focused on robustness, with slow but globally powerful algorithms. In this paper, we present an alternative registration approach that affords both speed and accuracy, with the goal of making pedobarographic image registration more practical for near-real-time laboratory and clinical applications. The current algorithm first extracts centroid-based curvature trajectories from pressure image contours, and then optimally matches these curvature profiles using optimization based on dynamic programming. Special cases of disconnected images (that occur in high-arched subjects, for example) are dealt with by introducing an artificial spatially linear bridge between adjacent image clusters. Two registration algorithms were developed: a 'geometric' algorithm, which exclusively matched geometry, and a 'hybrid' algorithm, which performed subsequent pseudo-optimization. After testing the two algorithms on 30 control image pairs considered in a previous study, we found that, when compared with previously published results, the hybrid algorithm improved overlap ratio (p=0.010), but both current algorithms had slightly higher mean-squared error, assumedly because they did not consider pixel intensity. Nonetheless, both algorithms greatly improved the computational efficiency (25+/-8 and 53+/-9 ms per image pair for geometric and hybrid registrations, respectively). These results imply that registration-based pixel-level pressure image analyses can, eventually, be implemented for practical clinical purposes. PMID:19647829
Cosmological spatial curvature probed by microwave polarization
Matzner, R.A.; Tolman, B.W.
1982-11-15
If there is a large-scale anisotropy in the expansion of the universe, the microwave background radiation is expected to be linearly polarized. This communication shows that spatial curvature is capable of rotating the polarization of the microwaves relative to its direction at last scattering, which is directly correlated with the expansion anisotropy (and so also the observed intensity anisotropy). In Friedmann-Robertson-Walker models of the universe with additional small expansion anisotropy, the observed rotation relative to the intensity anisotropy would be appreciable and constant over the celestial sphere in the closed (type IX) model, but in the flat and open models, it must either vanish (types I and V) or vary ina complicated way over the celestial sphere (type VII/sub h/). These facts suggest a clear observational test of the closure of the universe. Also, an ambiguity inherent in the homogeneity of the universe does not allow prediction of the direction of rotation; thus homogeneous universes possess a property which might be called ''handedness.''
BICEP2, the curvature perturbation and supersymmetry
NASA Astrophysics Data System (ADS)
Lyth, David H.
2014-11-01
The tensor fraction r simeq 0.16 found by BICEP2 corresponds to a Hubble parameter H simeq 1.0 × 1014 GeV during inflation. This has two implications for the (single-field) slow-roll inflation hypothesis. First, the inflaton perturbation must account for much more than 10% of the curvature perturbation ζ, which barring fine-tuning means that it accounts for practically all of it. It follows that a curvaton-like mechanism for generating ζ requires an alternative to slow roll such as k-inflation. Second, accepting slow-roll inflation, the excursion of the inflaton field is at least of order Planck scale. As a result, the flatness of the inflaton presumably requires a shift symmetry. I point out that if such is the case, the resulting potential is likely to have at least approximately the quadratic form suggested in 1983 by Linde, which is known to be compatible with the observed r as well as the observed spectral index ns. The shift symmetry does not require supersymmetry. Also, the big H may rule out a GUT by restoring the symmetry and producing fatal cosmic strings. The absence of a GUT would correspond to the absence of superpartners for the Standard Model particles, which indeed have yet to be found at the LHC.
Gradient expansion, curvature perturbations, and magnetized plasmas
Giovannini, Massimo; Rezaei, Zahra
2011-04-15
The properties of magnetized plasmas are always investigated under the hypothesis that the relativistic inhomogeneities stemming from the fluid sources and from the geometry itself are sufficiently small to allow for a perturbative description prior to photon decoupling. The latter assumption is hereby relaxed and predecoupling plasmas are described within a suitable expansion where the inhomogeneities are treated to a given order in the spatial gradients. It is argued that the (general relativistic) gradient expansion shares the same features of the drift approximation, customarily employed in the description of cold plasmas, so that the two schemes are physically complementary in the large-scale limit and for the low-frequency branch of the spectrum of plasma modes. The two-fluid description, as well as the magnetohydrodynamical reduction, is derived and studied in the presence of the spatial gradients of the geometry. Various solutions of the coupled system of evolution equations in the anti-Newtonian regime and in the quasi-isotropic approximation are presented. The relation of this analysis to the so-called separate universe paradigm is outlined. The evolution of the magnetized curvature perturbations in the nonlinear regime is addressed for the magnetized adiabatic mode in the plasma frame.
BICEP2, the curvature perturbation and supersymmetry
Lyth, David H.
2014-11-01
The tensor fraction r ≅ 0.16 found by BICEP2 corresponds to a Hubble parameter H ≅ 1.0 × 10{sup 14} GeV during inflation. This has two implications for the (single-field) slow-roll inflation hypothesis. First, the inflaton perturbation must account for much more than 10% of the curvature perturbation ζ, which barring fine-tuning means that it accounts for practically all of it. It follows that a curvaton-like mechanism for generating ζ requires an alternative to slow roll such as k-inflation. Second, accepting slow-roll inflation, the excursion of the inflaton field is at least of order Planck scale. As a result, the flatness of the inflaton presumably requires a shift symmetry. I point out that if such is the case, the resulting potential is likely to have at least approximately the quadratic form suggested in 1983 by Linde, which is known to be compatible with the observed r as well as the observed spectral index n{sub s}. The shift symmetry does not require supersymmetry. Also, the big H may rule out a GUT by restoring the symmetry and producing fatal cosmic strings. The absence of a GUT would correspond to the absence of superpartners for the Standard Model particles, which indeed have yet to be found at the LHC.
Nonlinear diffusion filtering influenced by mean curvature
NASA Astrophysics Data System (ADS)
Kollár, Michal; Mikula, Karol; Čunderlík, Róbert
2016-04-01
The presentation introduces a new nonlinear diffusion filtering method on closed surfaces such as a sphere, ellipsoid or the Earth's surface. Our new model extends the regularized surface Perona-Malik model by including a local extrema detector based on a mean curvature of processed data. The model is thus represented by a nonlinear diffusion equation which filters noise while preserves main edges, local extrema and details important for a correct interpretation of data. We define a surface finite-volume method to approximate numerically the nonlinear parabolic partial differential equation on a closed surface. The closed surface is approximated by a polyhedral surface created by planar triangles representing subdivision of an initial icosahedron grid and we use a piece-wise linear approximation of a solution in space and the backward Euler time discretization. Numerical experiments present nonlinear diffusion filtering of artificial data and real measurements, namely the GOCE satellite observations. They aim to point out a main advantage of the new nonlinear model which, on the contrary of Perona-Malik model, preserves local extremal values of filtered data.
NASA Astrophysics Data System (ADS)
Letcher, T.; Minder, J. R.
2015-12-01
High resolution regional climate models are used to characterize and quantify the snow albedo feedback (SAF) over the complex terrain of the Colorado Headwaters region. Three pairs of 7-year control and pseudo global warming simulations (with horizontal grid spacings of 4, 12, and 36 km) are used to study how the SAF modifies the regional climate response to a large-scale thermodynamic perturbation. The SAF substantially enhances warming within the Headwaters domain, locally as much as 5 °C in regions of snow loss. The SAF also increases the inter-annual variability of the springtime warming within Headwaters domain under the perturbed climate. Linear feedback analysis is used quantify the strength of the SAF. The SAF attains a maximum value of 4 W m-2 K-1 during April when snow loss coincides with strong incoming solar radiation. On sub-seasonal timescales, simulations at 4 km and 12 km horizontal grid-spacing show good agreement in the strength and timing of the SAF, whereas a 36km simulation shows greater discrepancies that are tired to differences in snow accumulation and ablation caused by smoother terrain. An analysis of the regional energy budget shows that transport by atmospheric motion acts as a negative feedback to regional warming, damping the effects of the SAF. On the mesoscale, this transport causes non-local warming in locations with no snow. The methods presented here can be used generally to quantify the role of the SAF in other regional climate modeling experiments.
Anisotropy of high-latitude nighttime F region irregularities
Livingston, R.C.; Rino, C.L.; Owen, J.; Tsunoda, R.T.
1982-12-01
The anisotropy of intermediate-scale, F region irregularities in the nighttime auroral zone is described. The study is based upon spaced-receiver phase scintillation measurements made with the Wideband satellite at Poker Flat, Alaska. A systematic dependence of irregularity anisotropy with local time and magnetic latitude is observed, suggesting convective control. Sheetlike irregularities are confined to the zone of east-west drift near the equatorward boundary of the auroral zone, and at the flow reversal, or Harang discontinuity, the cross-field extension of the sheets is reduced. The extension of rodlike irregularities, which are observed poleward of the zonal convection boundary, also shows apparent convection dominance. Mechanisms for convection control of the anisotropy are discussed.
Using Surface Curvature to Control the Dimerization of a Surface-Active Protein
NASA Astrophysics Data System (ADS)
Kurylowicz, Martin; Giuliani, Maximiliano; Dutcher, John
2012-02-01
Understanding the influence of surface geometry on adsorbed proteins promises new possibilities in biophysics, such as topographical catalysis, molecular recognition of geometric cues, and modulations of oligomerization or ligand binding. We have created nano-textured hydrophobic surfaces that are stable in buffer by spin coating polystyrene (PS) nanoparticles (NPs) to form patchy NP monolayers on a PS substrate, yielding flat and highly curved areas on the same sample. Moreover, we have separated surface chemistry from texture by floating a 10 nm thick film of monodisperse PS onto the NP-functionalized surface. Using Single Molecule Force Spectroscopy we have compared in situ the distribution of detachment lengths for proteins on curved surfaces to that measured on flat surfaces. We have shown that β-Lactoglobulin (β-LG), a surface-active protein which helps to stabilize oil droplets in milk, forms dimers on both flat PS surfaces and surfaces with a radius of curvature of 100 nm, whereas β-LG monomers exist for more highly curved surfaces with radii of curvature of 25 and 40 nm. It is surprising that rather large radii of curvature have such a strong influence on proteins whose radius is only ˜2 nm. Furthermore, the transition from dimer to monomer with changes in surface curvature offers promising applications for proteins whose function can be modified by their oligomerization state.
Effect of shockwave curvature on run distance observed with a modified wedge test
NASA Astrophysics Data System (ADS)
Lee, Richard; Dorgan, Robert J.; Sutherland, Gerrit; Benedetta, Ashley; Milby, Christopher
2012-03-01
The effect of wave curvature on shock initiation in PBXN-110 was investigated using a modified wedge test configuration. Various widths of PBXN-110 donor slabs were used to define the shockwave curvature introduced to wedge samples of the same explosive. The donor slabs were initiated with line-wave generators so that the shock from the donor would be the same shape, magnitude and duration across the entire input surface of the wedge. The shock parameters were varied for a given donor with PMMA spacers placed between the donor and the wedge sample. A high-speed electronic framing camera was used to observe where initiation occurred along the face of the wedge. Initiation always occurred at the center of the shock front instead of along the sides like that reported by others using a much smaller test format. Results were compared to CTH calculations to indicate if there were effects associated with highly curved shock fronts that could not be adequately predicted. The run distance predicted in CTH for a 50.8 mm wide donor slab (low curvature) compared favorably with experimental results. However, results from thinner donor slabs (higher curvature) indicate a more sensitive behavior than the simulations predicted.
Sim, SeungWoo; Kang, Seung-Ho; Lee, Sang-Hee
2015-02-01
Subterranean termites live underground and build tunnel networks to obtain food and nesting space. After obtaining food, termites return to their nests to transfer it. The efficiency of termite movement through the tunnels is directly connected to their survival. Tunnels should therefore be optimized to ensure highly efficient returns. An optimization factor that strongly affects movement efficiency is tunnel curvature. In the present study, we investigated traveling behavior in tunnels with different curvatures. We then characterized traveling behavior at the level of the individual using hidden Markov models (HMMs) constructed from the experimental data. To observe traveling behavior, we designed 5-cm long artificial tunnels that had different curvatures. The tunnels had widths (W) of 2, 3, or 4mm, and the linear distances between the two ends of the tunnels were (D) 20, 30, 40, or 50mm. High values of D indicate low curvature. We systematically observed the traveling behavior of Coptotermes formosanus shiraki and Reticulitermes speratus kyushuensis and measured the time (τ) required for a termite to pass through the tunnel. Using HMM models, we calculated τ for different tunnels and compared the results with the τ of real termites. We characterized the traveling behavior in terms of transition probability matrices (TPM) and emission probability matrices (EPM) of HMMs. We briefly discussed the construction of a sinusoidal-like tunnels in relation to the energy required for termites to pass through tunnels and provided suggestions for the development of more sophisticated HMMs to better understand termite foraging behavior. PMID:25562190
Yoshida, Kenji; Takagi, Toshimi
1999-07-01
Experimental and numerical studies are made of transient H{sub 2}/N{sub 2}--air counterflow diffusion flames unsteadily strained by an impinging micro jet. Two-dimensional temperature measurements by laser Rayleigh scattering method and numerical computations taking into account detailed chemical kinetics are conducted paying attention to transient local extinction and reignition in relation to the unsteadiness, flame curvature and preferential diffusion effects. The results are as follows. (1) Transient local flame extinction is observed where the micro jet impinges. But, the transient flame can survive instantaneously in spite of quite high stretch rate where the steady flame cannot exist. (2) Reignition is observed after the local extinction due to the micro air jet impingement. The temperature after reignition becomes significantly higher than that of the original flame. This high temperature is induced by the concentration of H{sub 2} species due to the preferential diffusion in relation to the concave curvature. The predicted behaviors of the local transient extinction and reignition are well confirmed by the experiments. (3) The reignition is induced after the formation of combustible premixed gas mixture and the consequent flame propagation. (4) The reignition is hardly observed after the extinction by micro fuel jet impingement. This is due to the dilution of H{sub 2} species induced by the preferential diffusion in relation to the convex curvature. (5) The maximum flame temperature cannot be rationalized by the stretch rate but changes widely depending on the unsteadiness and the flame curvature in relation with preferential diffusion.
Macintosh, Alison A; Davies, Thomas G; Pinhasi, Ron; Stock, Jay T
2015-06-01
Long bones respond to mechanical loading through functional adaptation in a suite of morphological characteristics that together ensure structural competence to in vivo loading. As such, adult bone structure is often used to make inferences about past behavior from archaeological remains. However, such biomechanical approaches often investigate change in just one aspect of morphology, typically cross-sectional morphology or trabecular structure. The relationship between longitudinal bone curvature and mobility patterns is less well understood, particularly in the tibia, and it is unknown how tibial curvature and diaphyseal cross-sectional geometry interact to meet the structural requirements of loading. This study examines tibial curvature and its relationship with diaphyseal cross-sectional geometry (CSG) and body size in preindustrial Central Europeans spanning ∼6150 years following the introduction of agriculture in the region. Anteroposterior centroid displacement from the proximo-distal longitudinal axis was quantified at nine diaphyseal section locations (collectively representative of diaphyseal curvature) in 216 tibial three-dimensional laser scans. Results documented significant and corresponding temporal declines in midshaft centroid displacement and CSG properties. Significant correlations were found between mid-diaphyseal centroid displacement and all mobility-related CSG properties, while the relationship weakened toward the diaphyseal ends. No significant relationship was found between centroid displacement and body size variables with the exception of the most distal section location. Results support a relationship between tibial curvature and cross-sectional geometry among prehistoric Central European agricultural populations, and suggest that changes in mechanical loading may have influenced a suite of morphological features related to bone adaptation in the lower limb. PMID:25677783
Spontaneous curvature of phosphatidic acid and lysophosphatidic acid.
Kooijman, Edgar E; Chupin, Vladimir; Fuller, Nola L; Kozlov, Michael M; de Kruijff, Ben; Burger, Koert N J; Rand, Peter R
2005-02-15
The formation of phosphatidic acid (PA) from lysophosphatidic acid (LPA), diacylglycerol, or phosphatidylcholine plays a key role in the regulation of intracellular membrane fission events, but the underlying molecular mechanism has not been resolved. A likely possibility is that PA affects local membrane curvature facilitating membrane bending and fission. To examine this possibility, we determined the spontaneous radius of curvature (R(0p)) of PA and LPA, carrying oleoyl fatty acids, using well-established X-ray diffraction methods. We found that, under physiological conditions of pH and salt concentration (pH 7.0, 150 mM NaCl), the R(0p) values of PA and LPA were -46 A and +20 A, respectively. Thus PA has considerable negative spontaneous curvature while LPA has the most positive spontaneous curvature of any membrane lipid measured to date. The further addition of Ca(2+) did not significantly affect lipid spontaneous curvature; however, omitting NaCl from the hydration buffer greatly reduced the spontaneous curvature of PA, turning it into a cylindrically shaped lipid molecule (R(0p) of -1.3 x 10(2) A). Our quantitative data on the spontaneous radius of curvature of PA and LPA at a physiological pH and salt concentration will be instrumental in developing future models of biomembrane fission. PMID:15697235
On 3-gauge transformations, 3-curvatures, and Gray-categories
Wang, Wei
2014-04-15
In the 3-gauge theory, a 3-connection is given by a 1-form A valued in the Lie algebra g, a 2-form B valued in the Lie algebra h, and a 3-form C valued in the Lie algebra l, where (g,h,l) constitutes a differential 2-crossed module. We give the 3-gauge transformations from one 3-connection to another, and show the transformation formulae of the 1-curvature 2-form, the 2-curvature 3-form, and the 3-curvature 4-form. The gauge configurations can be interpreted as smooth Gray-functors between two Gray 3-groupoids: the path 3-groupoid P{sub 3}(X) and the 3-gauge group G{sup L} associated to the 2-crossed module L, whose differential is (g,h,l). The derivatives of Gray-functors are 3-connections, and the derivatives of lax-natural transformations between two such Gray-functors are 3-gauge transformations. We give the 3-dimensional holonomy, the lattice version of the 3-curvature, whose derivative gives the 3-curvature 4-form. The covariance of 3-curvatures easily follows from this construction. This Gray-categorical construction explains why 3-gauge transformations and 3-curvatures have the given forms. The interchanging 3-arrows are responsible for the appearance of terms with the Peiffer commutator (, )
High School Dropout and Graduation Rates in the Central Region. Issues & Answers. REL 2008-No. 040
ERIC Educational Resources Information Center
Randel, Bruce; Moore, Laurie; Blair, Pam
2008-01-01
This report presents comprehensive and detailed information on grades 7-12 dropout rates and on high school graduation rates in the Central Region. Dropout and graduation rates are presented for the region as a whole and for each state in the region, by gender, race/ethnicity, locale, and grade. The rates provide a comprehensive reference for…
Morphology and phenomenology of the high-latitude E and F regions
NASA Technical Reports Server (NTRS)
Hunsucker, R. D.
1979-01-01
Results obtained at high latitude observatories on the behavior of E and F region ionization are presented including a bibliography. Behavior of E and F region ionization during day and night for quiet and disturbed conditions in the auroral and polar regions is described. Daily, seasonal and sunspot variations are also outlined.
Dynamic Curvature Steering Control for Autonomous Vehicle: Performance Analysis
NASA Astrophysics Data System (ADS)
Aizzat Zakaria, Muhammad; Zamzuri, Hairi; Amri Mazlan, Saiful
2016-02-01
This paper discusses the design of dynamic curvature steering control for autonomous vehicle. The lateral control and longitudinal control are discussed in this paper. The controller is designed based on the dynamic curvature calculation to estimate the path condition and modify the vehicle speed and steering wheel angle accordingly. In this paper, the simulation results are presented to show the capability of the controller to track the reference path. The controller is able to predict the path and modify the vehicle speed to suit the path condition. The effectiveness of the controller is shown in this paper whereby identical performance is achieved with the benchmark but with extra curvature adaptation capabilites.
Complete manifolds with bounded curvature and spectral gaps
NASA Astrophysics Data System (ADS)
Schoen, Richard; Tran, Hung
2016-08-01
We study the spectrum of complete noncompact manifolds with bounded curvature and positive injectivity radius. We give general conditions which imply that their essential spectrum has an arbitrarily large finite number of gaps. In particular, for any noncompact covering of a compact manifold, there is a metric on the base so that the lifted metric has an arbitrarily large finite number of gaps in its essential spectrum. Also, for any complete noncompact manifold with bounded curvature and positive injectivity radius we construct a metric uniformly equivalent to the given one (also of bounded curvature and positive injectivity radius) with an arbitrarily large finite number of gaps in its essential spectrum.
Measurement of the gravity-field curvature by atom interferometry.
Rosi, G; Cacciapuoti, L; Sorrentino, F; Menchetti, M; Prevedelli, M; Tino, G M
2015-01-01
We present the first direct measurement of the gravity-field curvature based on three conjugated atom interferometers. Three atomic clouds launched in the vertical direction are simultaneously interrogated by the same atom interferometry sequence and used to probe the gravity field at three equally spaced positions. The vertical component of the gravity-field curvature generated by nearby source masses is measured from the difference between adjacent gravity gradient values. Curvature measurements are of interest in geodesy studies and for the validation of gravitational models of the surrounding environment. The possibility of using such a scheme for a new determination of the Newtonian constant of gravity is also discussed. PMID:25615464
Numerical studies of transverse curvature effects on transonic flow stability
NASA Technical Reports Server (NTRS)
Macaraeg, M. G.; Daudpota, Q. I.
1992-01-01
A numerical study of transverse curvature effects on compressible flow temporal stability for transonic to low supersonic Mach numbers is presented for axisymmetric modes. The mean flows studied include a similar boundary-layer profile and a nonsimilar axisymmetric boundary-layer solution. The effect of neglecting curvature in the mean flow produces only small quantitative changes in the disturbance growth rate. For transonic Mach numbers (1-1.4) and aerodynamically relevant Reynolds numbers (5000-10,000 based on displacement thickness), the maximum growth rate is found to increase with curvature - the maximum occurring at a nondimensional radius (based on displacement thickness) between 30 and 100.
Motion on constant curvature spaces and quantization using Noether symmetries.
Bracken, Paul
2014-12-01
A general approach is presented for quantizing a metric nonlinear system on a manifold of constant curvature. It makes use of a curvature dependent procedure which relies on determining Noether symmetries from the metric. The curvature of the space functions as a constant parameter. For a specific metric which defines the manifold, Lie differentiation of the metric gives these symmetries. A metric is used such that the resulting Schrödinger equation can be solved in terms of hypergeometric functions. This permits the investigation of both the energy spectrum and wave functions exactly for this system. PMID:25554048
Motion on constant curvature spaces and quantization using noether symmetries
NASA Astrophysics Data System (ADS)
Bracken, Paul
2014-12-01
A general approach is presented for quantizing a metric nonlinear system on a manifold of constant curvature. It makes use of a curvature dependent procedure which relies on determining Noether symmetries from the metric. The curvature of the space functions as a constant parameter. For a specific metric which defines the manifold, Lie differentiation of the metric gives these symmetries. A metric is used such that the resulting Schrödinger equation can be solved in terms of hypergeometric functions. This permits the investigation of both the energy spectrum and wave functions exactly for this system.
Curvature perturbation and waterfall dynamics in hybrid inflation
Abolhasani, Ali Akbar; Firouzjahi, Hassan; Sasaki, Misao E-mail: firouz@mail.ipm.ir
2011-10-01
We investigate the parameter spaces of hybrid inflation model with special attention paid to the dynamics of waterfall field and curvature perturbations induced from its quantum fluctuations. Depending on the inflaton field value at the time of phase transition and the sharpness of the phase transition inflation can have multiple extended stages. We find that for models with mild phase transition the induced curvature perturbation from the waterfall field is too large to satisfy the COBE normalization. We investigate the model parameter space where the curvature perturbations from the waterfall quantum fluctuations vary between the results of standard hybrid inflation and the results obtained here.
Cervical cancer screening coverage in a high-incidence region
Navarro, Cibelli; da Fonseca, Allex Jardim; Sibajev, Alexander; Souza, Camila Iasmim de Andrade; Araújo, Daniela Souza; Teles, Daniele Aparecida de Freitas; de Carvalho, Stéphanie Gomes Lins; Cavalcante, Kyldery Wendell Moura; Rabelo, Wendell Lima
2015-01-01
OBJECTIVE To analyze the coverage of a cervical cancer screening program in a city with a high incidence of the disease in addition to the factors associated with non-adherence to the current preventive program. METHODS A cross-sectional study based on household surveys was conducted. The sample was composed of women between 25 and 59 years of age of the city of Boa Vista, RR, Northern Brazil who were covered by the cervical cancer screening program. The cluster sampling method was used. The dependent variable was participation in a women’s health program, defined as undergoing at least one Pap smear in the 36 months prior to the interview; the explanatory variables were extracted from individual data. A generalized linear model was used. RESULTS 603 women were analyzed, with an mean age of 38.2 years (SD = 10.2). Five hundred and seventeen women underwent the screening test, and the prevalence of adherence in the last three years was up to 85.7% (95%CI 82.5;88.5). A high per capita household income and recent medical consultation were associated with the lower rate of not being tested in multivariate analysis. Disease ignorance, causes, and prevention methods were correlated with chances of non-adherence to the screening system; 20.0% of the women were reported to have undergone opportunistic and non-routine screening. CONCLUSIONS The informed level of coverage is high, exceeding the level recommended for the control of cervical cancer. The preventive program appears to be opportunistic in nature, particularly for the most vulnerable women (with low income and little information on the disease). Studies on the diagnostic quality of cervicovaginal cytology and therapeutic schedules for positive cases are necessary for understanding the barriers to the control of cervical cancer. PMID:25741655
Curvature-driven assembly in soft matter.
Liu, Iris B; Sharifi-Mood, Nima; Stebe, Kathleen J
2016-07-28
Control over the spatial arrangement of colloids in soft matter hosts implies control over a wide variety of properties, ranging from the system's rheology, optics, and catalytic activity. In directed assembly, colloids are typically manipulated using external fields to form well-defined structures at given locations. We have been developing alternative strategies based on fields that arise when a colloid is placed within soft matter to form an inclusion that generates a potential field. Such potential fields allow particles to interact with each other. If the soft matter host is deformed in some way, the potential allows the particles to interact with the global system distortion. One important example is capillary assembly of colloids on curved fluid interfaces. Upon attaching, the particle distorts that interface, with an associated energy field, given by the product of its interfacial area and the surface tension. The particle's capillary energy depends on the local interface curvature. We explore this coupling in experiment and theory. There are important analogies in liquid crystals. Colloids in liquid crystals elicit an elastic energy response. When director fields are moulded by confinement, the imposed elastic energy field can couple to that of the colloid to define particle paths and sites for assembly. By improving our understanding of these and related systems, we seek to develop new, parallelizable routes for particle assembly to form reconfigurable systems in soft matter that go far beyond the usual close-packed colloidal structures.This article is part of the themed issue 'Soft interfacial materials: from fundamentals to formulation'. PMID:27298434
Curvature instability of a vortex ring
NASA Astrophysics Data System (ADS)
Fukumoto, Yasuhide; Hattori, Yuji
2005-03-01
A global stability analysis of Kelvin's vortex ring to three-dimensional disturbances of infinitesimal amplitude is made. The basic state is a steady asymptotic solution of the Euler equations, in powers of the ratio ɛ of the core radius to the ring radius, for an axisymmetric vortex ring with vorticity proportional to the distance from the symmetric axis. The effect of ring curvature appears at first order, in the form of a dipole field, and a local straining field, which is a quadrupole field, follows at second order. The eigenvalue problem of the Euler equations, retaining the terms to first order, is solved in closed form, in terms of the Bessel and the modified Bessel functions. We show that the dipole field causes a parametric resonance instability between a pair of Kelvin waves whose azimuthal wavenumbers are separated by 1. The most unstable mode occurs in the short-wavelength limit, under the constraint that the radial and the azimuthal wavenumbers are of the same magnitude, and the limiting value of maximum growth rate coincides with the value 165/256 ɛ obtained by Hattori & Fukumoto (Phys. Fluids, vol. 15, 2003, p. 3151) by means of the geometric optics method. The instability mechanism is traced to stretching of disturbance vorticity in the toroidal direction. In the absence of viscosity, the dipole effect outweighs the straining field effect of O(ɛ2) known as the Moore-Saffman-Tsai-Widnall instability. The viscosity acts to damp the former preferentially and these effects compete with each other.
High power, high brightness Al-free active region tapered lasers at 915 nm
NASA Astrophysics Data System (ADS)
Hassiaoui, I.; Michel, N.; Lecomte, M.; Parillaud, O.; Calligaro, M.; Krakowski, M.
2006-04-01
To achieve high power and high brightness, we have developed tapered diode lasers based on an Al-free active region at 915 nm. The material structure was grown by MOCVD (Metallorganic Chemical Vapor Deposition). It shows very low internal losses of only 0.5 cm -1, a very low transparency current density of 86 A/cm2, an excellent internal quantum efficiency of 86%, and a high characteristic temperature T 0 of 171 K. Based on these good results, at first, we have realised index-guided tapered lasers (IG1) with a narrow output width and a narrow taper angle, which deliver 1 W CW, together with an M2 beam quality parameter of 2.9 at 1/e2, and a narrow divergence angle in the slow axis of 5.1° FWHM and 7.5° at 1/e2. We have also fabricated new index-guided tapered lasers with a Clarinet shape, which were recently proposed to achieve high brightness together with a very narrow divergence angle. The Clarinet lasers deliver 0.6W CW, together with an excellent M2 beam quality factor of 1.2 at 1/e2, and a very narrow divergence angle in the slow axis of only 2.5° FWHM, and 3.9° at 1/e2, which is stable with current. These very narrow divergences are very advantageous for the collective coupling of tapered bars into optical fibers. In this work we have also investigated the influence of taper length on the output power and beam quality.
Holographic curvature perturbations in a cosmology with a space-like singularity
NASA Astrophysics Data System (ADS)
Ferreira, Elisa G. M.; Brandenberger, Robert
2016-07-01
We study the evolution of cosmological perturbations in an anti-de-Sitter (AdS) bulk through a cosmological singularity by mapping the dynamics onto the boundary conformal fields theory by means of the AdS/CFT correspondence. We consider a deformed AdS space-time obtained by considering a time-dependent dilaton which induces a curvature singularity in the bulk at a time which we call t = 0, and which asymptotically approaches AdS both for large positive and negative times. The boundary field theory becomes free when the bulk curvature goes to infinity. Hence, the evolution of the fluctuations is under better controle on the boundary than in the bulk. To avoid unbounded particle production across the bounce it is necessary to smooth out the curvature singularity at very high curvatures. We show how the bulk cosmological perturbations can be mapped onto boundary gauge field fluctuations. We evolve the latter and compare the spectrum of fluctuations on the infrared scales relevant for cosmological observations before and after the bounce point. We find that the index of the power spectrum of fluctuations is the same before and after the bounce.
Effect of Shockwave Curvature on Run Distance Observed with a Modified Wedge Test
NASA Astrophysics Data System (ADS)
Lee, Richard; Dorgan, Robert; Sutherland, Gerrit; Benedetta, Ashley; Milby, Christopher
2011-06-01
The effect of wave curvature on shock initiation in PBXN-110 was investigated using a modified wedge test configuration. Various thicknesses of PBXN-110 donor slabs were used to define the shockwave curvature introduced to wedge samples of the same explosive. The donor slabs were initiated with line-wave generators so that the introduced shock would be the same shape, magnitude and duration across the entire input surface of the wedge. The shock parameters were varied for a given donor thickness via different widths of PMMA spacers placed between the donor and the wedge. A framing camera was used to observe where initiation occurred along the face of the wedge. Initiation always occurred at the center of the shock front instead of the sides like that reported by others using a much smaller test format. Results were compared to CTH calculations to indicate if there were effects associated with highly curved shock fronts that could not be adequately predicted. The run distance predicted in CTH for a 50.8 mm thick donor slab (low curvature) compared favorably with experimental results. However, results from thinner donor slabs (higher curvature) indicate a more sensitive behavior than the simulations predicted.
Surface Curvature Relation to Protein Adsorption for Carbon-based Nanomaterials.
Gu, Zonglin; Yang, Zaixing; Chong, Yu; Ge, Cuicui; Weber, Jeffrey K; Bell, David R; Zhou, Ruhong
2015-01-01
The adsorption of proteins onto carbon-based nanomaterials (CBNs) is dictated by hydrophobic and π-π interactions between aliphatic and aromatic residues and the conjugated CBN surface. Accordingly, protein adsorption is highly sensitive to topological constraints imposed by CBN surface structure; in particular, adsorption capacity is thought to increase as the incident surface curvature decreases. In this work, we couple Molecular Dynamics (MD) simulations with fluorescence spectroscopy experiments to characterize this curvature dependence in detail for the model protein bovine serum albumin (BSA). By studying BSA adsorption onto carbon nanotubes of increasing radius (featuring descending local curvatures) and a flat graphene sheet, we confirm that adsorption capacity is indeed enhanced on flatter surfaces. Naïve fluorescence experiments featuring multi-walled carbon nanotubes (MWCNTs), however, conform to an opposing trend. To reconcile these observations, we conduct additional MD simulations with MWCNTs that match those prepared in experiments; such simulations indicate that increased mass to surface area ratios in multi-walled systems explain the observed discrepancies. In reduction, our work substantiates the inverse relationship between protein adsorption capacity and surface curvature and further demonstrates the need for subtle consideration in experimental and simulation design. PMID:26041015
Surface Curvature Relation to Protein Adsorption for Carbon-based Nanomaterials
Gu, Zonglin; Yang, Zaixing; Chong, Yu; Ge, Cuicui; Weber, Jeffrey K.; Bell, David R.; Zhou, Ruhong
2015-01-01
The adsorption of proteins onto carbon-based nanomaterials (CBNs) is dictated by hydrophobic and π-π interactions between aliphatic and aromatic residues and the conjugated CBN surface. Accordingly, protein adsorption is highly sensitive to topological constraints imposed by CBN surface structure; in particular, adsorption capacity is thought to increase as the incident surface curvature decreases. In this work, we couple Molecular Dynamics (MD) simulations with fluorescence spectroscopy experiments to characterize this curvature dependence in detail for the model protein bovine serum albumin (BSA). By studying BSA adsorption onto carbon nanotubes of increasing radius (featuring descending local curvatures) and a flat graphene sheet, we confirm that adsorption capacity is indeed enhanced on flatter surfaces. Naïve fluorescence experiments featuring multi-walled carbon nanotubes (MWCNTs), however, conform to an opposing trend. To reconcile these observations, we conduct additional MD simulations with MWCNTs that match those prepared in experiments; such simulations indicate that increased mass to surface area ratios in multi-walled systems explain the observed discrepancies. In reduction, our work substantiates the inverse relationship between protein adsorption capacity and surface curvature and further demonstrates the need for subtle consideration in experimental and simulation design. PMID:26041015
HYDROGEN FLUORIDE IN HIGH-MASS STAR-FORMING REGIONS
Emprechtinger, M.; Monje, R. R.; Lis, D. C.; Phillips, T. G.; Van der Tak, F. F. S.; Van der Wiel, M. H. D.; Neufeld, D.; Ceccarelli, C.
2012-09-10
Hydrogen fluoride (HF) has been established to be an excellent tracer of molecular hydrogen in diffuse clouds. In denser environments, however, the HF abundance has been shown to be approximately two orders of magnitude lower. We present Herschel/HIFI observations of HF J = 1-0 toward two high-mass star formation sites, NGC 6334 I and AFGL 2591. In NGC 6334 I the HF line is seen in absorption in foreground clouds and the source itself, while in AFGL 2591 HF is partially in emission. We find an HF abundance with respect to H{sub 2} of 1.5 Multiplication-Sign 10{sup -8} in the diffuse foreground clouds, whereas in the denser parts of NGC 6334 I we derive a lower limit on the HF abundance of 5 Multiplication-Sign 10{sup -10}. Lower HF abundances in dense clouds are most likely caused by freezeout of HF molecules onto dust grains in high-density gas. In AFGL 2591, the view of the hot core is obstructed by absorption in the massive outflow, in which HF is also very abundant (3.6 Multiplication-Sign 10{sup -8}) due to the desorption by sputtering. These observations provide further evidence that the chemistry of interstellar fluorine is controlled by freezeout onto gas grains.
Weak Line Quasars at High Redshift: Extremely High Accretion Rates or Anemic Broad-line Regions?
NASA Astrophysics Data System (ADS)
Shemmer, Ohad; Trakhtenbrot, Benny; Anderson, Scott F.; Brandt, W. N.; Diamond-Stanic, Aleksandar M.; Fan, Xiaohui; Lira, Paulina; Netzer, Hagai; Plotkin, Richard M.; Richards, Gordon T.; Schneider, Donald P.; Strauss, Michael A.
2010-10-01
We present Gemini-North K-band spectra of two representative members of the class of high-redshift quasars with exceptionally weak rest-frame ultraviolet emission lines (WLQs), SDSS J114153.34+021924.3 at z = 3.55 and SDSS J123743.08+630144.9 at z = 3.49. In both sources, we detect an unusually weak broad Hβ line and place tight upper limits on the strengths of their [O III] lines. Virial, Hβ-based black hole mass determinations indicate normalized accretion rates of L/L Edd=0.4 for these sources, which is well within the range observed for typical quasars with similar luminosities and redshifts. We also present high-quality XMM-Newton imaging spectroscopy of SDSS J114153.34+021924.3 and find a hard-X-ray photon index of Γ = 1.91+0.24 -0.22, which supports the virial L/L Edd determination in this source. Our results suggest that the weakness of the broad emission lines in WLQs is not a consequence of an extreme continuum-emission source but instead due to abnormal broad emission line region properties.
WEAK LINE QUASARS AT HIGH REDSHIFT: EXTREMELY HIGH ACCRETION RATES OR ANEMIC BROAD-LINE REGIONS?
Shemmer, Ohad; Trakhtenbrot, Benny; Netzer, Hagai; Anderson, Scott F.; Brandt, W. N.; Schneider, Donald P.; Diamond-Stanic, Aleksandar M.; Fan Xiaohui; Lira, Paulina; Plotkin, Richard M.; Richards, Gordon T.; Strauss, Michael A.
2010-10-20
We present Gemini-North K-band spectra of two representative members of the class of high-redshift quasars with exceptionally weak rest-frame ultraviolet emission lines (WLQs), SDSS J114153.34+021924.3 at z = 3.55 and SDSS J123743.08+630144.9 at z = 3.49. In both sources, we detect an unusually weak broad H{beta} line and place tight upper limits on the strengths of their [O III] lines. Virial, H{beta}-based black hole mass determinations indicate normalized accretion rates of L/L {sub Edd}=0.4 for these sources, which is well within the range observed for typical quasars with similar luminosities and redshifts. We also present high-quality XMM-Newton imaging spectroscopy of SDSS J114153.34+021924.3 and find a hard-X-ray photon index of {Gamma} = 1.91{sup +0.24} {sub -0.22}, which supports the virial L/L {sub Edd} determination in this source. Our results suggest that the weakness of the broad emission lines in WLQs is not a consequence of an extreme continuum-emission source but instead due to abnormal broad emission line region properties.
Technology Transfer Automated Retrieval System (TEKTRAN)
High groundwater pumping costs and rapidly declining water levels in the Texas High Plains makes it imperative to improve irrigation water management for sustainability and economic viability. In this area, agriculture uses approximately 90% of groundwater withdrawals. Accurate regional evapotrans...
NASA Astrophysics Data System (ADS)
Phillips, G.; Robinson, J.; Glen, R.; Roberts, J.
2016-05-01
The middle to late Permian Hunter Bowen Event is credited with the development of orogenic curvature in the southern New England Orogen, yet contention surrounds the structural dynamics responsible for the development of this curvature. Debate is largely centred on the roles of orogen parallel strike-slip and orogen normal extension and contraction to explain the development of curvature. To evaluate the dynamic history of the Hunter Bowen Event, we present new kinematic reconstructions of the Tamworth Belt. The Tamworth Belt formed as a Carboniferous forearc basin and was subsequently inverted during the Hunter Bowen Event. Kinematic reconstructions of the Tamworth Belt are based on new maps and cross-sections built from a synthesis of best-available mapping, chronostratigraphic data and new interpretations of depth-converted seismic data. The following conclusions are made from our study: (i) the Hunter Bowen Event was dominantly driven by margin normal contraction (east-west shortening; present-day coordinates), and; (ii) variations in structural style along the strike of the Tamworth Belt can be explained by orthogonal vs. oblique inversion, which reflects the angular relationship between the principal shortening vector and continental-arc margin. Given these conclusions, we suggest that curvature around the controversial Manning Bend was influenced by the presence of primary curvature in the continental margin, and that the Hastings Block was translated along a sinistral strike-slip fault system that formed along this oblique (with respect to the regional east-west extension and convergence direction) part of the margin. Given the available temporal data, the translation of the Hastings Block took place in the Early Permian (Asselian) and therefore preceded the Hunter Bowen Event. Accordingly, we suggest that the Hunter Bowen Event was dominantly associated with enhancing curvature that was either primary in origin, or associated with fault block translation
High velocity compact clouds in the sagittarius C region
Tanaka, Kunihiko; Oka, Tomoharu; Matsumura, Shinji; Nagai, Makoto; Kamegai, Kazuhisa
2014-03-01
We report the detection of extremely broad emission toward two molecular clumps in the Galactic central molecular zone. We have mapped the Sagittarius C complex (–0.°61 < l < –0.°27, –0.°29 < b < 0.°04) in the HCN J = 4-3, {sup 13}CO J = 3-2, and H{sup 13}CN J = 1-0 lines with the ASTE 10 m and NRO 45 m telescopes, detecting bright emission with 80-120 km s{sup –1} velocity width (in full-width at zero intensity) toward CO–0.30–0.07 and CO–0.40–0.22, which are high velocity compact clouds (HVCCs) identified with our previous CO J = 3-2 survey. Our data reveal an interesting internal structure of CO–0.30–0.07 comprising a pair of high velocity lobes. The spatial-velocity structure of CO–0.40–0.22 can be also understood as a multiple velocity component, or a velocity gradient across the cloud. They are both located on the rims of two molecular shells of about 10 pc in radius. Kinetic energies of CO–0.30–0.07 and CO–0.40–0.22 are (0.8-2) × 10{sup 49} erg and (1-4) × 10{sup 49} erg, respectively. We propose several interpretations of their broad emission: collision between clouds associated with the shells, bipolar outflow, expansion driven by supernovae (SNe), and rotation around a dark massive object. These scenarios cannot be discriminated because of the insufficient angular resolution of our data, though the absence of a visible energy source associated with the HVCCs seems to favor the cloud-cloud collision scenario. Kinetic energies of the two molecular shells are 1 × 10{sup 51} erg and 0.7 × 10{sup 51} erg, which can be furnished by multiple SN or hypernova explosions in 2 × 10{sup 5} yr. These shells are candidates of molecular superbubbles created after past active star formation.
NASA Astrophysics Data System (ADS)
Guo, Lianghui; Gao, Rui; Meng, Xiaohong; Zhang, Guoli
2015-10-01
In work discussed in this paper the characteristics of both the most positive and most negative curvatures of a magnetic anomaly were analyzed, and a new approach for detection of the edges of magnetic anomalies is proposed. The new approach, called the hybrid positive-and-negative curvature approach, combines the most positive and most negative curvatures into one curvature by formula adjustments and weighted summation, combining the advantages of the two curvatures to improve edge detection. This approach is suitable for vertically magnetized or reduction-to-pole anomalies, which avoids the complexity of magnetic anomalies caused by oblique magnetization. Testing on synthetic vertically magnetized magnetic anomalies data demonstrated that the hybrid approach traces the edges of magnetic source bodies effectively, discriminates between high and low magnetism intuitively, and is better than approaches based solely on use of the most positive or most negative curvature. Testing on reduced-to-pole magnetic anomalies data around the ocean basin of the South China Sea showed that the hybrid approach enables better edge detection than the most positive or most negative curvatures. On the basis of the features of the reduced-to-pole magnetic anomalies and their hybrid curvature, we suggest the tectonic boundary between the southwestern subbasin and the eastern subbasin of the South China Sea ranges from the northeastern edge of the Zhongsha Islands in the southeast direction to the northeastern edge of the Reed Bank.
Supporting Students through Participation in the Regional High School Summer School Program
ERIC Educational Resources Information Center
Zhao, Huafang; McGaughey, Trisha A.; Wade, Julie
2014-01-01
The Office of Shared Accountability (OSA) in Montgomery County (Maryland) Public Schools (MCPS) conducted a study of the MCPS Regional High School Summer School Program. Academic intervention programs (AIPs) in MCPS, including the Regional High School Summer School Program, aim to help students gain lost credits and earn credits needed for…
An efficient means to mitigate wavefront curvature effects in polar format processed SAR imagery
NASA Astrophysics Data System (ADS)
Linnehan, Robert; Yasuda, Mark; Doerry, Armin
2012-06-01
Synthetic aperture radar (SAR) images processed using the polar format algorithm (PFA) may exhibit distortion if the curvature of the spherical wavefronts are not accounted for. The distortion manifests in geometric shifts and defocusing of targets, and intensifies as distances between pixels and the scene reference position increase. In this work, we demonstrate a method to mitigate the effects of wavefront curvature by applying localized (space-variant) phase corrections to sub-regions selected from the polar format processed image. The modified sub-images are then reassembled into a full image. To minimize discontinuities in the reconstructed image, the spatially variant phase adjustments are made to regions larger than the sub-images, and pared down before being reinserted into the complete image. The result is a SAR process that retains the efficiency of the PFA, yet avoids scene size limitations due to wavefront curvature distortions. The method is illustrated and validated using simulations and real data collected by the General Atomics Aeronautical Systems, Inc. (GA-ASI) Lynx® Multi-mode Radar System.
Curvature Control of Silicon Microlens for THz Dielectric Antenna
NASA Technical Reports Server (NTRS)
Lee, Choonsup; Chattopadhyay, Goutam; Cooper, Ken; Mehdi, Imran
2012-01-01
We have controlled the curvature of silicon microlens by changing the amount of photoresist in order to microfabricate hemispherical silicon microlens which can improve the directivity and reduce substrate mode losses.
16. Detail of curvature of northern parapet, with 1932 concrete ...
16. Detail of curvature of northern parapet, with 1932 concrete extension of parapet in foreground, facing east. - Dubbs Bridge, Spinnerstown Road (State Route 2031) spanning Hosensack Creek, Dillingerville, Lehigh County, PA
Wavefront curvature of an opticaly pumped waveguide laser
Tacke, M.
1983-05-01
The influence of inhomogeneous gain on the wavefront shape is discussed for waveguide lasers. As an example, the curvature of the EH(11) mode of an optically pumped FIR laser is computed, its influence on the output beam is discussed.
Curvature-Squared Cosmology In The First-Order Formalism
NASA Technical Reports Server (NTRS)
Shahid-Saless, Bahman
1993-01-01
Paper presents theoretical study of some of general-relativistic ramifications of gravitational-field energy density proportional to R - alpha R(exp 2) (where R is local scalar curvature of space-time and alpha is a constant).
Electric current measurement using fiber-optic curvature sensor
NASA Astrophysics Data System (ADS)
Di, Haiting; Xin, Ying; Sun, Suping
2016-02-01
A novel fiber-optic curvature sensor, which can measure curvature directly, has been developed in recent years. The electric current measurements system based on fiber-optic curvature sensor and electromagnetic principle is developed. A fiber-optic curvature sensor is bonded to a thin-walled cantilever and two circular magnet targets with the same parameters are configured at the tip of the cantilever symmetrically. In this case, the throughput of the sensor will be changed due to the bending deformation of cantilever, which is proportional to the electromagnetic force caused by measured electric current. Direct and alternate characteristics of the proposed measurement system are studied experimentally. The results show that the measurement errors are within the range of ±5.5 mA and the corresponding accuracy is within 1% at the current measurement range from -300 mA to 300 mA, which indicate the feasibility of the proposed measurement system.
Constraints on the geometric and dynamic spatial curvature
NASA Astrophysics Data System (ADS)
Yu, Bo
2015-10-01
In this paper, the geometric and dynamic spatial curvature parameters of the Universe are constrained by type Ia supernova, baryon acoustic oscillation, and cosmic microwave background data. Compared with the previous result, a more stringent constraint is obtained, especially for the dynamic spatial curvature in the case of variable dark energy. No evidence is found that the geometric spatial curvature deviates from the dynamic spatial curvature, which is consistent with general relativity. In the case of dark energy with constant equation of state, it is found that -8.4 ×1 0-3≤ΩKgeo≤6.6 ×1 0-3 (95% C.L.). This supports the hypothesis of a flat Universe in a very general meaning.
Bacterial cell curvature through mechanical control of cell growth
Cabeen, Matthew T; Charbon, Godefroid; Vollmer, Waldemar; Born, Petra; Ausmees, Nora; Weibel, Douglas B; Jacobs-Wagner, Christine
2009-01-01
The cytoskeleton is a key regulator of cell morphogenesis. Crescentin, a bacterial intermediate filament-like protein, is required for the curved shape of Caulobacter crescentus and localizes to the inner cell curvature. Here, we show that crescentin forms a single filamentous structure that collapses into a helix when detached from the cell membrane, suggesting that it is normally maintained in a stretched configuration. Crescentin causes an elongation rate gradient around the circumference of the sidewall, creating a longitudinal cell length differential and hence curvature. Such curvature can be produced by physical force alone when cells are grown in circular microchambers. Production of crescentin in Escherichia coli is sufficient to generate cell curvature. Our data argue for a model in which physical strain borne by the crescentin structure anisotropically alters the kinetics of cell wall insertion to produce curved growth. Our study suggests that bacteria may use the cytoskeleton for mechanical control of growth to alter morphology. PMID:19279668
Effects of anisotropy and spatial curvature on the pre-big-bang scenario
NASA Astrophysics Data System (ADS)
Clancy, Dominic; Lidsey, James E.; Tavakol, Reza
1998-08-01
A class of exact, anisotropic cosmological solutions to the vacuum Brans-Dicke theory of gravity is considered within the context of the pre-big-bang scenario. Included in this class are the Bianchi type III, V and VIh models and the spatially isotropic, negatively curved Friedmann-Robertson-Walker universe. The effects of large anisotropy and spatial curvature are determined. In contrast with a negatively curved Friedmann-Robertson-Walker model, there exist regions of the parameter space in which the combined effects of curvature and anisotropy prevent the occurrence of inflation. When inflation is possible, the necessary and sufficient conditions for successful pre-big-bang inflation are more stringent than in the isotropic models. The initial state for these models is established and corresponds in general to a gravitational plane wave.
NASA Astrophysics Data System (ADS)
Osipov, Sergey; Dogar, Mohammad; Stenchikov, Georgiy
2016-04-01
High-latitude winter warming after strong equatorial volcanic eruptions caused by circulation changes associated with the anomalously positive phase of Arctic Oscillation is a subject of active research during recent decade. But severe winter cooling in the Middle East observed after the Mt. Pinatubo eruption of 1991, although recognized, was not thoroughly investigated. These severe regional climate perturbations in the Middle East cannot be explained by solely radiative volcanic cooling, which suggests that a contribution of forced circulation changes could be important and significant. To better understand the mechanisms of the Middle East climate response and evaluate the contributions of dynamic and radiative effects we conducted a comparative study using Geophysical Fluid Dynamics Laboratory global High Resolution Atmospheric Model (HiRAM) with the effectively "regional-model-resolution" of 25-km and the regional Weather Research and Forecasting (WRF) model focusing on the eruption of Mount Pinatubo on June 15, 1991 followed by a pronounced positive phase of the Arctic Oscillation. The WRF model has been configured over the Middle East and North Africa (MENA) region. The WRF code has been modified to interactively account for the radiative effect of volcanic aerosols. Both HiRAM and WRF capture the main features of the MENA climate response and show that in winter the dynamic effects in the Middle East prevail the direct radiative cooling from volcanic aerosols.
A novel curvature-controllable steerable needle for percutaneous intervention.
Bui, Van Khuyen; Park, Sukho; Park, Jong-Oh; Ko, Seong Young
2016-08-01
Over the last few decades, flexible steerable robotic needles for percutaneous intervention have been the subject of significant interest. However, there still remain issues related to (a) steering the needle's direction with less damage to surrounding tissues and (b) increasing the needle's maximum curvature for better controllability. One widely used approach is to control the fixed-angled bevel-tip needle using a "duty-cycle" algorithm. While this algorithm has shown its applicability, it can potentially damage surrounding tissue, which has prevented the widespread adoption of this technology. This situation has motivated the development of a new steerable flexible needle that can change its curvature without axial rotation, while at the same time producing a larger curvature. In this article, we propose a novel curvature-controllable steerable needle. The proposed robotic needle consists of two parts: a cannula and a stylet with a bevel-tip. The curvature of the needle's path is controlled by a control offset, defined by the offset between the bevel-tip and the cannula. As a result, the necessity of rotating the whole needle's body is decreased. The duty-cycle algorithm is utilized to a limited degree to obtain a larger radius of curvature, which is similar to a straight path. The first prototype of 0.46 mm (outer diameter) was fabricated and tested with both in vitro gelatin phantom and ex vivo cow liver tissue. The maximum curvatures measured 0.008 mm(-1) in 6 wt% gelatin phantom, 0.0139 mm(-1) in 10 wt% gelatin phantom, and 0.0038 mm(-1) in cow liver. The experimental results show a linear relationship between the curvature and the control offset, which can be utilized for future implementation of this control algorithm. PMID:27206444
Layered devices having surface curvature and method of constructing same
Woodbury, Richard C.; Perkins, Raymond T.; Thorne, James M.
1989-01-01
A method of treating a substrate having first and second sides with corresponding oppositely facing first and second surfaces, to produce curvature in the first surface. The method includes the steps of removing material, according to a predetermined pattern, from the second side of the substrate, and applying a stress-producing film of material to at least one surface of the substrate to thereby cause the substrate to bend to produce the desired curvature in the first surface.
Topology of codimension-one foliations of nonnegative curvature
Bolotov, Dmitry V
2013-05-31
We show that a transversely oriented C{sup 2}-foliation of codimension one with nonnegative Ricci curvature on a closed orientable manifold is a foliation with almost no holonomy. This allows us to decompose the manifold into blocks on which this foliation has a simple structure. We also show that a manifold homeomorphic to a 5-dimensional sphere does not admit a codimension-one C{sup 2}-foliation with nonnegative sectional curvature. Bibliography: 29 titles.
Hedgehogs in higher dimensional gravity with curvature self-interactions
NASA Astrophysics Data System (ADS)
Giovannini, Massimo
2001-04-01
Static solutions of the higher dimensional Einstein-Hilbert gravity supplemented by quadratic curvature self-interactions are discussed in the presence of hedgehog configurations along the transverse dimensions. The quadratic part of the action is parametrized in terms of the (ghost-free) Euler-Gauss-Bonnet curvature invariant. Spherically symmetric profiles of the transverse metric admit exponentially decaying warp factors both for positive and negative bulk cosmological constants.
Simple yet accurate noncontact device for measuring the radius of curvature of a spherical mirror
Spiridonov, Maxim; Toebaert, David
2006-09-10
An easily reproducible device is demonstrated to be capable of measuring the radii of curvature of spherical mirrors, both convex and concave, without resorting to high-end interferometric or tactile devices. The former are too elaborate for our purposes,and the latter cannot be used due to the delicate nature of the coatings applied to mirrors used in high-power CO2 laser applications. The proposed apparatus is accurate enough to be useful to anyone using curved optics and needing a quick way to assess the values of the radii of curvature, be it for entrance quality control or trouble shooting an apparently malfunctioning optical system. Specifically, the apparatus was designed for checking 50 mm diameter resonator(typically flat or tens of meters concave) and telescope (typically some meters convex and concave) mirrors for a high-power CO2 laser, but it can easily be adapted to any other type of spherical mirror by a straightforward resizing.
Two distinct regions of response drive differential growth in Vigna root electrotropism
NASA Technical Reports Server (NTRS)
Wolverton, C.; Mullen, J. L.; Ishikawa, H.; Evans, M. L.
2000-01-01
Although exogenous electric fields have been reported to influence the orientation of plant root growth, reports of the ultimate direction of differential growth have been contradictory. Using a high-resolution image analysis approach, the kinetics of electrotropic curvature in Vigna mungo L. roots were investigated. It was found that curvature occurred in the same root toward both the anode and cathode. However, these two responses occurred in two different regions of the root, the central elongation zone (CEZ) and distal elongation zone (DEZ), respectively. These oppositely directed responses could be reproduced individually by a localized electric field application to the region of response. This indicates that both are true responses to the electric field, rather than one being a secondary response to an induced gravitropic stimulation. The individual responses differed in the type of differential growth giving rise to curvature. In the CEZ, curvature was driven by inhibition of elongation, whereas curvature in the DEZ was primarily due to stimulation of elongation. This stimulation of elongation is consistent with the growth response of the DEZ to other environmental stimuli.
Some Effects of Spacetime Curvature in General Relativity
NASA Astrophysics Data System (ADS)
McClune, James Cephas
This dissertation is about the physical effects of spacetime curvature and consists of the following three major topics: Relativistic tidal impulse, a new derivation of the Bel-Robinson tensor, and the study of the Bel-Robinson tensor for the rotating gravitational wave metric. In the study of relativistic tidal impulse, one considers the impulse per unit mass acting on a highly relativistic particle as it passes by a rotating mass. For the spacetime metric describing the field of the rotating mass, the 'weak' field approximation of the uncharged Kerr metric is employed. It follows from this relativistic treatment that the impulse, as felt by the particle, is in general velocity dependent for any given impact parameter, as opposed to the Newtonian result that the impulse is only dependent on the impact parameter. Some physical consequences of this fact are briefly explored. The Bel-Robinson tensor is a fourth rank tensor quadratic in the spacetime curvature and has been known since 1958. The new derivation of the Bel-Robinson tensor is the most significant part of this dissertation. This new derivation puts on a solid footing the physical meaning of the Bel-Robinson tensor and the analogy to electromagnetism that it draws on for its construction. In the Fermi frame used in this derivation, a gravitational Faraday tensor, gravitoelectromagnetic field equations, and a gravitational analog of the Lorentz force law can be identified. The gravitational Faraday tensor is used to construct an energy-momentum-stress tensor for the gravitational field in complete analogy with that of electromagnetism. This construction is then identified, via a limiting procedure, as the projection of the Bel-Robinson tensor on the tetrad frame of the fiducial observer of the Fermi frame. The former, less rigorous, arguments which were used to construct the Bel-Robinson tensor gave a less rigorous interpretation of some of its elements as the Poynting 4-vector. This derivation provides a
Spontaneous curvature as a regulator of the size of virus capsids
NASA Astrophysics Data System (ADS)
Šiber, Antonio; Majdandžić, Antonio
2009-08-01
We investigate the physical reasons underlying the high monodispersity of empty virus capsids assembled in thermodynamical equilibrium in conditions of favorable pH and ionic strength. We propose that the high fidelity of the assembly results from the effective spontaneous curvature of the viral protein assemblies and the corresponding bending rigidity that penalizes curvatures which are larger and smaller from the spontaneous one. On the example of hepatitis B virus, which has been thoroughly studied experimentally in the context of interest to us, we estimate the magnitude of bending rigidity that is needed to suppress the appearance of aberrant capsid structures (˜60kBT) . Our approach also demonstrates that the aberrant capsids that can be classified within the Caspar-Klug framework are in most circumstances likely to be smaller from the regular ones, in agreement with the experimental findings.
Urade, Vikrant N; Bollmann, Luis; Kowalski, Jonathan D; Tate, Michael P; Hillhouse, Hugh W
2007-04-10
The double-gyroid phase of nanoporous silica films has been shown to possess facile mass-transport properties and may be used as a mold to fabricate a variety of highly ordered inverse double-gyroid metal and semiconductor films. This phase exists only over a very small region of the binary phase diagram for most surfactants, and it has been very difficult to synthesize metal oxide films with this structure by evaporation-induced self-assembly (EISA). Here, we show the interplay of the key parameters needed to synthesize these structures reproducibly and show that the interfacial curvature may be systematically controlled. Grazing angle of incidence small-angle X-ray scattering (GISAXS) is used to determine the structure and orientation of nanostructured silica films formed by EISA from dilute silica/(poly(ethylene oxide)-b-poly(propylene oxide)-b-alkyl) surfactant solutions. Four different highly ordered film structures are observed by changing only the concentration of the surfactant, the relative humidity during dip-coating, and the aging time of the solution prior to coating. The highly ordered films progress from rhombohedral (Rm) to 2D rectangular (c2m) to double-gyroid (distorted Iad) to lamellar systematically as interfacial curvature decreases. Under all experimental conditions investigated, increasing the aging time of the coating solution was found to decrease the interfacial curvature. In particular, this parameter was critical to being able to synthesize highly ordered, pure-phase double-gyroid films. The key role of the aging time is shown via processing diagrams that map out the interplay between the aging time, composition, and relative humidity. 29Si nuclear magnetic resonance (NMR) spectroscopy and solution-phase small-angle X-ray scattering (SAXS) of the aged coating solutions presented in part I of this series are then used to interpret the effects of aging prior to dip-coating. Specifically, it was found that a predictive model based on volume
A novel approach in assessment of root canal curvature
Sadeghi, Shiva; Poryousef, Vahideh
2009-01-01
Introduction: The purpose of this in vitro study was to introduce a new method to describe root canal curvatures and to assess the degree of curvature of human permanent mandibular teeth with curved root canals. Materials and Methods: One hundred and thirty five mesial root canals of mandibular first and second molar teeth were selected. Access cavities were prepared. After inserting a K-file size #10 into each canal, radiographs were taken. Canal curvature was determined by measuring the Schneider angle, canal access angle, as well as the canal radius, length, height and curvature starting distance on scanned radiographs using a computerized image processing system. Data was evaluated statistically using Pearson correlation. Results: The mean canal access angle (CAA) and Schneider angle (S) were 8.04◦ (3.46) and 19◦ (6.99), respectively. The Pearson correlation analysis found significant positive correlation between S and CAA (r=0.826, P<0.0001). Negative correlations were found between radius and length (r= –0.4, P<0.0001), radius and Schneider angle (r= –0.4, P<0.0001), radius and CAA (r= –0.24, P=0.004) and CAA and curvature starting distance (r= 0.4, P<0.0001). There was no correlation between height and distance (r=0.013, P=0.789), as well as CAA and height (r=0.654, P=0.001). Conclusion: Under the limitations of this study, the results indicated that the shape of root canal curvature can be more accurately described using two angles, Schneider in combination with Canal access angle. The related parameters included radius, length, distance and height of curvature. [Iranian Endodontic Journal 2009;4(4):131-4] PMID:24019833
Wasnik, Vaibhav; Wingreen, Ned S.; Mukhopadhyay, Ranjan
2015-01-01
Recent in vivo experiments suggest that in the bacterium, Bacillus subtilis, the cue for the localization of the small sporulation protein, SpoVM, an essential factor in spore coat formation, is curvature of the bacterial plasma membrane. In vitro measurements of SpoVM adsorption to vesicles of varying sizes also find high sensitivity of adsorption to vesicle radius. This curvature-dependent adsorption is puzzling given the orders of magnitude difference in length scale between an individual protein and the radius of curvature of the cell or vesicle, suggesting protein clustering on the membrane. Here we develop a minimal model to study the relationship between curvature-dependent membrane adsorption and clustering of SpoVM. Based on our analysis, we hypothesize that the radius dependence of SpoVM adsorption observed in vitro is governed primarily by membrane tension, while for in-vivo localization of SpoVM, we propose a highly sensitive mechanism for curvature sensing based on the formation of macroscopic protein clusters on the membrane. PMID:25625300
High spatial resolution Mg/Al maps of the western Crisium and Sulpicius Gallus regions
NASA Technical Reports Server (NTRS)
Schonfeld, E.
1982-01-01
High spatial resolution Mg/Al ratio maps of the western Crisium and Sulpicius Gallus regions of the moon are presented. The data is from the X-ray fluorescence experiment and the image enhancement technique in the Laplacian subtraction method using a special least-squares version of the Laplacian to reduce noise amplification. In the highlands region west of Mare Crisium several relatively small patches of smooth material have high local Mg/Al ratio similar to values found in mare sites, suggesting volcanism in the highlands. In the same highland region there were other smooth areas with no high Mg/Al local values and they are probably Cayley Formation material produced by impact mass wasting. The Sulpicius Gallus region has variable Mg/Al ratios. In this region there are several high Mg/Al ratio spots, two of which occur at the highland-mare interface. Another high Mg/Al ratio area corresponds to the Sulpicius Gallus Rima I region. The high Mg/Al ratio material in the Sulpicius Gallus region is probably pyroclastic.
Do ultrasound-guided regional blocks signify a new paradigm in high-risk patients?
Bendtsen, Thomas F; Haskins, Stephen; Kølsen Petersen, Jens Aage; Børglum, Jens
2016-06-01
It has been suggested for many years that regional anaesthesia is advantageous in high-risk patients, either as the sole anaesthetic or in combination with general anaesthesia. Regional techniques are safe and even more so when guided by ultrasound. In the high-risk patient population, ultrasound-guided regional anaesthesia (UGRA) can help decrease risk of perioperative morbidity and improve short-term as well as long-term outcomes, particularly in the orthopaedic, vascular, oncologic and chronic pain patient populations. Nevertheless, complications do still occur and benefits of a specific regional nerve blockade need to be weighed against potential risks on an individual basis. The emergence of reasonably priced, easy-to-use ultrasound machines facilitates regional anaesthesia, and this kind of anaesthesia may become the standard of care in high-risk patients. PMID:27396806
Phase grating wavefront curvature sensor based on liquid crystal spatial light modulator
NASA Astrophysics Data System (ADS)
Chen, Bo; Li, Xiaoyang; Yang, Xu
2015-08-01
The phase grating wavefront curvature sensor based on liquid crystal spatial light modulator is introduced. A close-loop phase retrieval method based on Eigen functions of Laplacian is proposed, and its accuracy and efficiency are analyzed through numerical experiments of atmospheric phase retrieval. The results show that the close-loop phase retrieval method has a high accuracy. Moreover, it is stable regardless of modal cross coupling.
Turned head--adducted hip--truncal curvature syndrome.
Hamanishi, C; Tanaka, S
1994-01-01
One hundred and eight neonates and infants who showed the clinical triad of a head turned to one side, adduction contracture of the hip joint on the occipital side of the turned head, and truncal curvature, which we named TAC syndrome, were studied. These cases included seven with congenital and five with late infantile dislocations of the hip joint and 14 who developed muscular torticollis. Forty one were among 7103 neonates examined by one of the authors. An epidemiological analysis confirmed the aetiology of the syndrome to be environmental. The side to which the head was turned and that of the adducted hip contracture showed a high correlation with the side of the maternal spine on which the fetus had been lying. TAC syndrome is an important asymmetrical deformity that should be kept in mind during neonatal examination, and may be aetiologically related to the unilateral dislocation of the hip joint, torticollis, and infantile scoliosis which develop after a vertex presentation. Images PMID:8048823
Hamiltonian analysis of curvature-squared gravity with or without conformal invariance
NASA Astrophysics Data System (ADS)
KlusoÅ, Josef; Oksanen, Markku; Tureanu, Anca
2014-03-01
We analyze gravitational theories with quadratic curvature terms, including the case of conformally invariant Weyl gravity, motivated by the intention to find a renormalizable theory of gravity in the ultraviolet region, yet yielding general relativity at long distances. In the Hamiltonian formulation of Weyl gravity, the number of local constraints is equal to the number of unstable directions in phase space, which in principle could be sufficient for eliminating the unstable degrees of freedom in the full nonlinear theory. All the other theories of quadratic type are unstable—a problem appearing as ghost modes in the linearized theory. We find that the full projection of the Weyl tensor onto a three-dimensional hypersurface contains an additional fully traceless component, given by a quadratic extrinsic curvature tensor. A certain inconsistency in the literature is found and resolved: when the conformal invariance of Weyl gravity is broken by a cosmological constant term, the theory becomes pathological, since a constraint required by the Hamiltonian analysis imposes the determinant of the metric of spacetime to be zero. In order to resolve this problem by restoring the conformal invariance, we introduce a new scalar field that couples to the curvature of spacetime, reminiscent of the introduction of vector fields for ensuring the gauge invariance.
Wang, Q.; Li, M.; Lou, Edmond H. M.; Wong, M. S.
2015-01-01
Background Non-ionizing radiation imaging assessment has been advocated for the patients with adolescent idiopathic scoliosis (AIS). As one of the radiation-free methods, ultrasound imaging has gained growing attention in scoliosis assessment over the past decade. The center of laminae (COL) method has been proposed to measure the spinal curvature in the coronal plane of ultrasound image. However, the reliability and validity of this ultrasound method have not been validated in the clinical setting. Objectives To evaluate the reliability and validity of clinical ultrasound imaging on lateral curvature measurements of AIS with their corresponding magnetic resonance imaging (MRI) measurements. Methods Thirty curves (ranged 10.2°–68.2°) from sixteen patients with AIS were eligible for this study. The ultrasound scan was performed using a 3-D ultrasound unit within the same morning of MRI examination. Two researchers were involved in data collection of these two examinations. The COL method was used to measure the coronal curvature in ultrasound image, compared with the Cobb method in MRI. The intra- and inter-rater reliability of the COL method was evaluated by intra-class correlation coefficient (ICC). The validity of this method was analyzed by paired Student’s t-test, Bland–Altman statistics and Pearson correlation coefficient. The level of significance was set as 0.05. Results The COL method showed high intra- and inter-rater reliabilities (both with ICC (2, K) >0.9, p<0.05) to measure the coronal curvature. Compared with Cobb method, COL method showed no significant difference (p<0.05) when measuring coronal curvature. Furthermore, Bland-Altman method demonstrated an agreement between these two methods, and Pearson’s correlation coefficient (r) was high (r>0.9, p<0.05). Conclusion The ultrasound imaging could provide a reliable and valid measurement of spinal curvature in the coronal plane using the COL method. Further research is needed to validate the
Barlev, Omri; Golub, Michael A; Friesem, Asher A; Nathan, Menachem
2012-12-01
Surface-relief resonance-domain diffraction gratings with deep and dense grooves provide considerable changes in light propagation direction, wavefront curvature, and nearly 100% Bragg diffraction efficiency usually attributed only to volume optical holograms. In this paper, we present design, computer simulation, fabrication, and experimental results of binary resonance-domain diffraction gratings in the visible spectral region. Performance of imperfectly fabricated diffraction groove profiles was optimized by controlling the DC and the depth of the grooves. Indeed, more than 97% absolute Bragg diffraction efficiency was measured at the 635 nm wavelength with binary gratings having periods of 520 nm and groove depths of about 1000 nm, fabricated by direct electron-beam lithography and reactive ion etching. PMID:23207376
Wang, Mengben; Jiménez, Claudia Villarroel
2015-01-01
An analysis of the annual mean temperature (TMEAN) (1961–2010) has revealed that warming amplification (altitudinal amplification and regional amplification) is a common feature of major high-elevation regions across the globe against the background of global warming since the mid-20th century. In this study, the authors further examine whether this holds for annual mean minimum temperature (TMIN) and annual mean maximum temperature (TMAX) (1961–2010) on a global scale. The extraction method of warming component of altitude, and the paired region comparison method were used in this study. Results show that a significant altitudinal amplification trend in TMIN (TMAX) is detected in all (four) of the six high-elevation regions tested, and the average magnitude of altitudinal amplification trend for TMIN (TMAX) [0.306±0.086 °C km-1(0.154±0.213 °C km-1)] is substantially larger (smaller) than TMEAN (0.230±0.073 °C km-1) during the period 1961–2010. For the five paired high- and low-elevation regions available, regional amplification is detected in the four high-elevation regions for TMIN and TMAX (respectively or as a whole). Qualitatively, highly (largely) consistent results are observed for TMIN (TMAX) compared with those for TMEAN. PMID:26461461
NASA Astrophysics Data System (ADS)
Misawa, Ayanori; Hirata, Kenji; Seeber, Leonard; Arai, Kohsaku; Nakamura, Yasuyuki; Rahardiawan, Riza; Udrekh; Fujiwara, Toshiya; Kinoshita, Masataka; Baba, Hisatoshi; Kameo, Katsura; Adachi, Keita; Sarukawa, Hiroshi; Tokuyama, Hidekazu; Permana, Haryadi; Djajadihardja, Yusuf S.; Ashi, Juichiro
2014-01-01
To investigate detailed fault distributions and shallow geological structure offshore northwestern Sumatra, we obtained high-resolution Multi-Channel Seismic (MCS) reflection data around the Sunda Trench, trench slope, and forearc high regions offshore northwestern Sumatra. In general, trench-parallel anticlinal ridges are distributed from trench slope region to forearc high region. Two kinds of different vergence systems are characterized in the Sumatra forearc region; landward vergence is dominant in the lower trench slope region, and seaward vergence is dominant in the forearc high region. Moreover, piggyback or slope basins are recognized between anticlinal ridges. Deformation in the uppermost part of these basins, that is referred to ‘recent’ deformation in this paper, can be identified not only along major thrusts but also between major thrusts and the lower trench slope, suggesting these are related to recently active faulting. Several but the largest number of such deformation are distributed along a major thrust located in the middle of the forearc high region, whereas few are done along other major thrusts.
Representation of tactile curvature in macaque somatosensory area 2
Connor, Charles E.; Hsiao, Steven S.
2013-01-01
Tactile shape information is elaborated in a cortical hierarchy spanning primary (SI) and secondary somatosensory cortex (SII). Indeed, SI neurons in areas 3b and 1 encode simple contour features such as small oriented bars and edges, whereas higher order SII neurons represent large curved contour features such as angles and arcs. However, neural coding of these contour features has not been systematically characterized in area 2, the most caudal SI subdivision in the postcentral gyrus. In the present study, we analyzed area 2 neural responses to embossed oriented bars and curved contour fragments to establish whether curvature representations are generated in the postcentral gyrus. We found that many area 2 neurons (26 of 112) exhibit clear curvature tuning, preferring contours pointing in a particular direction. Fewer area 2 neurons (15 of 112) show preferences for oriented bars. Because area 2 response patterns closely resembled SII patterns, we also compared area 2 and SII response time courses to characterize the temporal dynamics of curvature synthesis in the somatosensory system. We found that curvature representations develop and peak concurrently in area 2 and SII. These results reveal that transitions from orientation tuning to curvature selectivity in the somatosensory cortical hierarchy occur within SI rather than between SI and SII. PMID:23536717
Intermembrane Docking Reactions Are Regulated by Membrane Curvature
Kunding, Andreas H.; Mortensen, Michael W.; Christensen, Sune M.; Bhatia, Vikram K.; Makarov, Ivan; Metzler, Ralf; Stamou, Dimitrios
2011-01-01
The polymorphism of eukaryotic cellular membranes is a tightly regulated and well-conserved phenotype. Recent data have revealed important regulatory roles of membrane curvature on the spatio-temporal localization of proteins and in membrane fusion. Here we quantified the influence of membrane curvature on the efficiency of intermembrane docking reactions. Using fluorescence microscopy, we monitored the docking of single vesicle–vesicle pairs of different diameter (30–200 nm) and therefore curvature, as mediated by neuronal soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) and streptavidin-biotin. Surprisingly, the intermembrane docking efficiency exhibited an ∼30–60 fold enhancement as a function of curvature. In comparison, synaptotagmin and calcium accelerate SNARE-mediated fusion in vitro by a factor of 2–10. To explain this finding, we formulated a biophysical model. On the basis of our findings, we propose that membrane curvature can regulate intermembrane tethering reactions and consequently any downstream process, including the fusion of vesicles and possibly viruses with their target membranes. PMID:22261058
The weighted curvature approximation in scattering from sea surfaces
NASA Astrophysics Data System (ADS)
Guérin, Charles-Antoine; Soriano, Gabriel; Chapron, Bertrand
2010-07-01
A family of unified models in scattering from rough surfaces is based on local corrections of the tangent plane approximation through higher-order derivatives of the surface. We revisit these methods in a common framework when the correction is limited to the curvature, that is essentially the second-order derivative. The resulting expression is formally identical to the weighted curvature approximation, with several admissible kernels, however. For sea surfaces under the Gaussian assumption, we show that the weighted curvature approximation reduces to a universal and simple expression for the off-specular normalized radar cross-section (NRCS), regardless of the chosen kernel. The formula involves merely the sum of the NRCS in the classical Kirchhoff approximation and the NRCS in the small perturbation method, except that the Bragg kernel in the latter has to be replaced by the difference of a Bragg and a Kirchhoff kernel. This result is consistently compared with the resonant curvature approximation. Some numerical comparisons with the method of moments and other classical approximate methods are performed at various bands and sea states. For the copolarized components, the weighted curvature approximation is found numerically very close to the cut-off invariant two-scale model, while bringing substantial improvement to both the Kirchhoff and small-slope approximation. However, the model is unable to predict cross-polarization in the plane of incidence. The simplicity of the formulation opens new perspectives in sea state inversion from remote sensing data.
ERIC Educational Resources Information Center
Cullen, Joseph Patrick
2010-01-01
Consolidated Regional High Schools (RHSs) have replaced traditional Community High Schools (CHSs) in many nonmetropolitan communities. Consolidation purports to offer cost savings that, in theory, enable nonmetropolitan districts to provide a wider array of instructional opportunities to their students. Nonetheless, critics argue that the benefits…
VizieR Online Data Catalog: Parallaxes of high mass star forming regions (Reid+, 2014)
NASA Astrophysics Data System (ADS)
Reid, M. J.; Menten, K. M.; Brunthaler, A.; Zheng, X. W.; Dame, T. M.; Xu, Y.; Wu, Y.; Zhang, B.; Sanna, A.; Sato, M.; Hachisuka, K.; Choi, Y. K.; Immer, K.; Moscadelli, L.; Rygl, K. L. J.; Bartkiewicz, A.
2016-04-01
Table1 lists the parallaxes and proper motions of 103 regions of high-mass star formation measured with Very Long Baseline Interferometry (VLBI) techniques, using the National Radio Astronomy Observatory's Very Long Baseline Array (VLBA), the Japanese VLBI Exploration of Radio Astrometry (VERA; http://veraserver.mtk.nao.ac.jp) project, and the European VLBI Network (EVN). We have include three red supergiants (NML Cyg, S Per, VY CMa) as indicative of high-mass star forming regions. (2 data files).
NASA Astrophysics Data System (ADS)
Lin, Jinyong; Zeng, Yongyi; Lin, Juqiang; Wang, Jing; Li, Ling; Huang, Zufang; Li, Buhong; Zeng, Haishan; Chen, Rong
2014-03-01
Raman spectroscopy was employed to detect lipid variation occurring in type II diabetic erythrocyte membrane (EM) without using exogenous reagents. In high-wavenumber (HW) region, significant Raman spectral differences between diabetic and normal EM are observed at 2850, 2873, 2885, 2935, and 2965 cm-1, which are mainly related to lipid in EM. Based on principal component analysis, the diagnostic accuracy of HW region for diabetes detection is 98.8%, which is much higher than that of low-wavenumber region (82.9%). The results suggest that EM HW Raman region has great promise for the reagent-free and non-invasive detection of type II diabetes.
Minezaki, Yoshiaki; Homma, Keiichi; Kinjo, Akira R; Nishikawa, Ken
2006-06-16
Human transcriptional regulation factors, such as activators, repressors, and enhancer-binding factors are quite different from their prokaryotic counterparts in two respects: the average sequence in human is more than twice as long as that in prokaryotes, while the fraction of sequence aligned to domains of known structure is 31% in human transcription factors (TFs), less than half of that in bacterial TFs (72%). Intrinsically disordered (ID) regions were identified by a disorder-prediction program, and were found to be in good agreement with available experimental data. Analysis of 401 human TFs with experimental evidence from the Swiss-Prot database showed that as high as 49% of the entire sequence of human TFs is occupied by ID regions. More than half of the human TFs consist of a small DNA binding domain (DBD) and long ID regions frequently sandwiching unassigned regions. The remaining TFs have structural domains in addition to DBDs and ID regions. Experimental studies, particularly those with NMR, revealed that the transactivation domains in unbound TFs are usually unstructured, but become structured upon binding to their partners. The sequences of human and mouse TF orthologues are 90.5% identical despite a high incidence of ID regions, probably reflecting important functional roles played by ID regions. In general ID regions occupy a high fraction in TFs of eukaryotes, but not in prokaryotes. Implications of this dichotomy are discussed in connection with their functional roles in transcriptional regulation and evolution. PMID:16697407
Hybrid region merging method for segmentation of high-resolution remote sensing images
NASA Astrophysics Data System (ADS)
Zhang, Xueliang; Xiao, Pengfeng; Feng, Xuezhi; Wang, Jiangeng; Wang, Zuo
2014-12-01
Image segmentation remains a challenging problem for object-based image analysis. In this paper, a hybrid region merging (HRM) method is proposed to segment high-resolution remote sensing images. HRM integrates the advantages of global-oriented and local-oriented region merging strategies into a unified framework. The globally most-similar pair of regions is used to determine the starting point of a growing region, which provides an elegant way to avoid the problem of starting point assignment and to enhance the optimization ability for local-oriented region merging. During the region growing procedure, the merging iterations are constrained within the local vicinity, so that the segmentation is accelerated and can reflect the local context, as compared with the global-oriented method. A set of high-resolution remote sensing images is used to test the effectiveness of the HRM method, and three region-based remote sensing image segmentation methods are adopted for comparison, including the hierarchical stepwise optimization (HSWO) method, the local-mutual best region merging (LMM) method, and the multiresolution segmentation (MRS) method embedded in eCognition Developer software. Both the supervised evaluation and visual assessment show that HRM performs better than HSWO and LMM by combining both their advantages. The segmentation results of HRM and MRS are visually comparable, but HRM can describe objects as single regions better than MRS, and the supervised and unsupervised evaluation results further prove the superiority of HRM.
NASA Technical Reports Server (NTRS)
Mitrofanov, I. G.; Litvak, M. L.; Kozyrev, A. S.; Sanin, A. B.; Tretyakov, V. I.; Kuzmin, R. O.; Boynton, W. V.; Hamara, D. K.; Shinohara, C.; Saunders, R. S.
2004-01-01
The measurements by neutron detectors on Odyssey have revealed two large poleward regions with large depression of flux of epithermal and high energy neutrons. The flux of neutrons from Mars is known to be produced by the bombardment of the surface layer by galactic cosmic rays. The leakage flux of epithermal and fast neutrons has regional variation by a factor of 10 over the surface of Mars. These variations are mainly produced by variations of hydrogen content in the shallow subsurface. On Mars hydrogen is associated with water. Therefore, the Northern and Southern depressions of neutron emission could be identified as permafrost regions with very high content of water ice. These regions are much larger than the residual polar caps, and could contain the major fraction of subsurface water ice. Here we present the results of HEND neutron data deconvolution for these regions and describe the similarities and differences between them.
NASA Technical Reports Server (NTRS)
Mitrofanov, I. G.; Litvak, M. L.; Kozyrev, A. S.; Sanin, A. B.; Tretyakov, V. I.; Kuzmin, R. O.; Boynton, W. V.; Hamara, D. K.; Shinohara, C.; Saunders, R. S.
2004-01-01
The measurements by neutron detectors on Odyssey have revealed two large poleward regions with large depression of flux of epithermal and high energy neutrons [1-3]. The flux of neutrons from Mars is known to be produced by the bombardment of the surface layer by galactic cosmic rays. The leakage flux of epithermal and fast neutrons has regional variation by a factor of 10 over the surface of Mars (e.g. see [3- 5]). These variations are mainly produced by variations of hydrogen content in the shallow subsurface. On Mars hydrogen is associated with water. Therefore, the Northern and Southern depressions of neutron emission could be identified as permafrost regions with very high content of water ice [1-5]. These regions are much larger than the residual polar caps, and could contain the major fraction of subsurface water ice. Here we present the results of HEND neutron data deconvolution for these regions and describe the similarities and differences between them.
Nonlinear dynamics of the tearing mode with two-fluid and curvature effects in tokamaks
Meshcheriakov, Dmytro; Maget, Patrick; Garbet, Xavier; Lütjens, Hinrich; Beyer, Peter
2014-01-15
Curvature and diamagnetic effects are both known to have an influence on tearing mode dynamics. In this paper, we investigate the impact of these effects on the nonlinear stability and saturation of a (2, 1) island using non-linear two-fluid MHD simulations and we apply our results to Tore Supra experiments, where its behavior is not well understood from the single fluid MHD model. Simulations show that a metastable state induced by diamagnetic effect exists for this mode and that it also produces a reduction of the saturated island size, in presence of toroidal curvature. The mode is found to be nonlinearly destabilized by a seed island and it saturates at a macroscopic level causing a significant confinement degradation. The interpretation of dual states, with either no island on q = 2 or a large one, observed on discharges with high non inductive current source on Tore Supra, is revisited.
Influence of the bonding front propagation on the wafer stack curvature
Navarro, E.; Bréchet, Y.; Barthelemy, A.; Radu, I.; Pardoen, T.; Raskin, J.-P.
2014-08-11
The influence of the dynamics of the direct wafer bonding process on the curvature of the final wafer stack is investigated. An analytical model for the final curvature of the bonded wafers is developed, as a function of the different load components acting during the bonding front propagation, using thin plate theory and considering a strain discontinuity locked at the bonding interface. Experimental profiles are measured for different bonding conditions and wafer thicknesses. A very good agreement with the model prediction is obtained and the influence of the thin air layer trapped in-between the two wafers is demonstrated. The proposed model contributes to further improvement of the bonding process, in particular, for the stacking of layers of electronic devices, which requires a high accuracy of wafer-to-wafer alignment and a very low distortion level.
Effect of Tension and Curvature of Skin on Insertion Characteristics of Microneedle Array
NASA Astrophysics Data System (ADS)
Tachikawa, Hiroto; Takano, Naoki; Nishiyabu, Kazuaki; Miki, Norihisa; Ami, Yoshimichi
Recent MEMS (micro electro mechanical system) fabrication techniques have made it possible to produce painless microneedles precisely enough to be inserted into epidermis layer penetrating the stratum corneum of human skin. This paper presents a testing procedure to evaluate the insertion characteristics of microneedle array using cultured human skin considering the tension and the curvature. First, the biaxial strain applied to the cultured human skin was measured by optical technique with image processing. It was found that almost constant strain could be successfully given within a certain area and that error factors in the experiment except the thickness variation of the cultured skin were negligible. Next, using a microneedle square array for brain machine interface (BMI) application, the effects of biaxial tension and the curvature on insertion characteristics were discussed. Within the above mentioned area with high strain, the needles were successfully inserted.
Poxviruses Encode a Reticulon-Like Protein that Promotes Membrane Curvature
Erlandson, Karl J.; Bisht, Himani; Weisberg, Andrea S.; Hyun, Seong-In; Hansen, Bryan T.; Fischer, Elizabeth R.; Hinshaw, Jenny E.; Moss, Bernard
2016-01-01
Poxviruses are enveloped DNA viruses that replicate within the cytoplasm. The first viral structures are crescents and spherical particles with a lipoprotein membrane bilayer thought to be derived from the endoplasmic reticulum (ER). We determined that A17, a conserved viral transmembrane protein essential for crescent formation, forms homo-oligomers and shares topological features with cellular reticulon-like proteins, which promote membrane curvature and contribute to the tubular structure of the ER. When the purified A17 protein was incorporated into liposomes, 25 nm diameter vesicles and tubules formed at low and high A17 concentrations, respectively. In addition, intracellular expression of A17, in the absence of other viral structural proteins, transformed the ER into aggregated 3-dimensional tubular networks. We suggest that A17 is a viral reticulon-like protein that contributes to curvature during biogenesis of the poxvirus membrane. PMID:26923595
Kinetics for phototropic curvature by etiolated seedlings of Arabidopsis thaliana
NASA Technical Reports Server (NTRS)
Orbovic, V.; Poff, K. L.
1991-01-01
An infrared-imaging system has been used to study the influence of gravity on the kinetics of first positive phototropism. The development of phototropic curvature of etiolated seedlings of Arabidopsis thaliana was measured in the absence of visible radiation. Following a pulse of blue light, stationary seedlings curved to a maximum of approximately 16 degrees about 80 minutes after stimulation. The seedlings then curved upward again or straightened by about 6 degrees during the subsequent 100 minutes. Seedlings rotated on a clinostat reached a similar maximum curvature following photostimulation. These seedlings maintained that curvature for 30 to 40 minutes before subsequently straightening to the same extent as the stationary seedlings. It is concluded that straightening is not a consequence of gravitropism, although gravity has some effect on the phototropism kinetics.
Robust disparity estimation based on color monogenic curvature phase.
Zang, Di; Li, Jie; Zhang, Dongdong; Zhang, Junqi
2012-07-01
Disparity estimation for binocular images is an important problem for many visual tasks such as 3D environment reconstruction, digital hologram, virtual reality, robot navigation, etc. Conventional approaches are based on brightness constancy assumption to establish spatial correspondences between a pair of images. However, in the presence of large illumination variation and serious noisy contamination, conventional approaches fail to generate accurate disparity maps. To have robust disparity estimation in these situations, we first propose a model - color monogenic curvature phase to describe local features of color images by embedding the monogenic curvature signal into the quaternion representation. Then a multiscale framework to estimate disparities is proposed by coupling the advantages of the color monogenic curvature phase and mutual information. Both indoor and outdoor images with large brightness variation are used in the experiments, and the results demonstrate that our approach can achieve a good performance even in the conditions of large illumination change and serious noisy contamination. PMID:22772192
Numerical Estimation of the Curvature of Biological Surfaces
NASA Technical Reports Server (NTRS)
Todd, P. H.
1985-01-01
Many biological systems may profitably be studied as surface phenomena. A model consisting of isotropic growth of a curved surface from a flat sheet is assumed. With such a model, the Gaussian curvature of the final surface determines whether growth rate of the surface is subharmonic or superharmonic. These properties correspond to notions of convexity and concavity, and thus to local excess growth and local deficiency of growth. In biological models where the major factors controlling surface growth are intrinsic to the surface, researchers thus gained from geometrical study information on the differential growth undergone by the surface. These ideas were applied to an analysis of the folding of the cerebral cortex, a geometrically rather complex surface growth. A numerical surface curvature technique based on an approximation to the Dupin indicatrix of the surface was developed. A metric for comparing curvature estimates is introduced, and considerable numerical testing indicated the reliability of this technique.
Tensor analysis and curvature in quantum space-time
Namsrai, K.
1987-03-01
Introducing quantum space-time into physics by means of the transformation language of noncommuting coordinates gives a simple scheme of generalizing the tensor analysis. The general covariance principle for the quantum space-time case is discussed, within which one can obtain the covariant structure of basic tensor quantities and the motion equation for a particle in a gravitational field. Definitions of covariant derivatives and curvature are also generalized in the give case. It turns out that the covariant structure of the Riemann-Christoffel curvature tensor is not preserved in quantum space-time. However, if the curvature tensor R/sub ..mu.. nu lambda chi/(z) is redetermined up to the value of the L/sup 2/ term, then its covariant structure is achieved, and it, in turn, allows them to reconstruct the Einstein equation in quantum space-time.
Exploiting cantilever curvature for noise reduction in atomic force microscopy.
Labuda, Aleksander; Grütter, Peter H
2011-01-01
Optical beam deflection is a widely used method for detecting the deflection of atomic force microscope (AFM) cantilevers. This paper presents a first order derivation for the angular detection noise density which determines the lower limit for deflection sensing. Surprisingly, the cantilever radius of curvature, commonly not considered, plays a crucial role and can be exploited to decrease angular detection noise. We demonstrate a reduction in angular detection shot noise of more than an order of magnitude on a home-built AFM with a commercial 450 μm long cantilever by exploiting the optical properties of the cantilever curvature caused by the reflective gold coating. Lastly, we demonstrate how cantilever curvature can be responsible for up to 45% of the variability in the measured sensitivity of cantilevers on commercially available AFMs. PMID:21280834
Studies of the effects of curvature on dilution jet mixing
NASA Astrophysics Data System (ADS)
Holdeman, James D.; Srinivasan, Ram; Reynolds, Robert S.; White, Craig D.
1992-02-01
An analytical program was conducted using both three-dimensional numerical and empirical models to investigate the effects of transition liner curvature on the mixing of jets injected into a confined crossflow. The numerical code is of the TEACH type with hybrid numerics; it uses the power-law and SIMPLER algorithms, an orthogonal curvilinear coordinate system, and an algebraic Reynolds stress turbulence model. From the results of the numerical calculations, an existing empirical model for the temperature field downstream of single and multiple rows of jets injected into a straight rectangular duct was extended to model the effects of curvature. Temperature distributions, calculated with both the numerical and empirical models, are presented to show the effects of radius of curvature and inner and outer wall injection for single and opposed rows of cool dilution jets injected into a hot mainstream flow.
Curvature-Controlled Defect Localization in Elastic Surface Crystals
NASA Astrophysics Data System (ADS)
Jiménez, Francisco López; Stoop, Norbert; Lagrange, Romain; Dunkel, Jörn; Reis, Pedro M.
2016-03-01
We investigate the influence of curvature and topology on crystalline dimpled patterns on the surface of generic elastic bilayers. Our numerical analysis predicts that the total number of defects created by adiabatic compression exhibits universal quadratic scaling for spherical, ellipsoidal, and toroidal surfaces over a wide range of system sizes. However, both the localization of individual defects and the orientation of defect chains depend strongly on the local Gaussian curvature and its gradients across a surface. Our results imply that curvature and topology can be utilized to pattern defects in elastic materials, thus promising improved control over hierarchical bending, buckling, or folding processes. Generally, this study suggests that bilayer systems provide an inexpensive yet valuable experimental test bed for exploring the effects of geometrically induced forces on assemblies of topological charges.
Characterization of inherent curvature in DNA lacking polyadenine runs.
McNamara, P T; Harrington, R E
1991-07-01
Sequence-directed DNA curvature is most commonly associated with AA dinucleotides in the form of polyadenine runs. We demonstrate inherent curvature in DNA which lacks AA/TT dinucleotides using the criteria of polyacrylamide gel mobility and efficiency of DNA cyclization. These studies are based upon two 21-base pair synthetic DNA fragments designed to exhibit fixed curvature according to deflections made to the helical axis by non-AA dinucleotide stacks. Repeats of these sequences display anomalously slow migration in polyacrylamide gels. Moreover, both sequences describe helical conformations that are closed into circles by DNA ligase at much smaller sizes than is typical of nondeformed DNA. Chemical cleavage of these DNA molecules with hydroxyl radical is also consistent with local variation in helical conformation at specific dinucleotide steps. PMID:1648100
Efficient seeding and defragmentation of curvature streamlines for colonic polyp detection
NASA Astrophysics Data System (ADS)
Zhao, Lingxiao; Botha, Charl P.; Truyen, Roel; Vos, Frans M.; Post, Frits H.
2008-03-01
Many computer aided diagnosis (CAD) schemes have been developed for colon cancer detection using Virtual Colonoscopy (VC). In earlier work, we developed an automatic polyp detection method integrating flow visualization techniques, that forms part of the CAD functionality of an existing Virtual Colonoscopy pipeline. Curvature streamlines were used to characterize polyp surface shape. Features derived from curvature streamlines correlated highly with true polyp detections. During testing with a large number of patient data sets, we found that the correlation between streamline features and true polyps could be affected by noise and our streamline generation technique. The seeding and spacing constraints and CT noise could lead to streamline fragmentation, which reduced the discriminating power of our streamline features. In this paper, we present two major improvements of our curvature streamline generation. First, we adapted our streamline seeding strategy to the local surface properties and made the streamline generation faster. It generates a significantly smaller number of seeds but still results in a comparable and suitable streamline distribution. Second, based on our observation that longer streamlines are better surface shape descriptors, we improved our streamline tracing algorithm to produce longer streamlines. Our improved techniques are more effcient and also guide the streamline geometry to correspond better to colonic surface shape. These two adaptations support a robust and high correlation between our streamline features and true positive detections and lead to better polyp detection results.
The Effect of Cooling Passage Aspect Ratio on Curvature Heat Transfer Enhancement
NASA Technical Reports Server (NTRS)
Meyer, Michael L.
1997-01-01
A series of electrically heated tube experiments was performed to investigate the effect of high aspect ratio on curvature heat transfer enhancement in uniformly heated rectangular cooling passages. Three hardware geometries were tested: a baseline straight aspect ratio 10 tube, an aspect ratio 1 (square) tube with a 45 deg. curve, and an aspect ratio 10 tube with a 45 deg. curve. Gaseous nitrogen with the following properties was used as the coolant: ambient inlet temperature, pressures to 8.3 MPa, wall-to-bulk temperature ratios less than two, and Reynolds numbers based on hydraulic diameter ranging from 250,000 to 1,600,000. The measured curvature enhancement factors were compared to values predicted by three previously published models which had been developed for low aspect ratio tubes. The models were shown to be valid for the high aspect ratio tube as well the low aspect ratio tube, indicating that aspect ratio had little impact on the curvature heat transfer enhancement in these tests.
Wang, Dan; Yin, Yajun; Wu, Jiye; Wang, Xugui; Zhong, Zheng
2016-01-01
The interaction potential between a curved surface body and a particle located on the surface of the body is studied in this paper. Based on the negative exponential pair potential (1/R(n)) between particles, the interaction potential is proved to be of the curvature-based form, i.e., it can be written as a function of curvatures of the surface. Idealized numerical experiments are designed to test the accuracy of curvature-based potential. Based on the curvature-based potential, propositions below are confirmed: a highly curved surface body will induce driving forces on the particle located on the surface, and curvatures and the gradients of curvatures are essential factors forming the driving forces. In addition, the tangent driving force acting on the particle from the curved surface body is studied. Based on duality, the following rule is proved: for a convex or concave curved body sharing the same curved surface, the curvature-based interaction potential between them and a particle on the surface can make up the potential of a particle in the whole space. PMID:26538079
Regional temperature and precipitation changes under high-end (≥4°C) global warming.
Sanderson, M G; Hemming, D L; Betts, R A
2011-01-13
Climate models vary widely in their projections of both global mean temperature rise and regional climate changes, but are there any systematic differences in regional changes associated with different levels of global climate sensitivity? This paper examines model projections of climate change over the twenty-first century from the Intergovernmental Panel on Climate Change Fourth Assessment Report which used the A2 scenario from the IPCC Special Report on Emissions Scenarios, assessing whether different regional responses can be seen in models categorized as 'high-end' (those projecting 4°C or more by the end of the twenty-first century relative to the preindustrial). It also identifies regions where the largest climate changes are projected under high-end warming. The mean spatial patterns of change, normalized against the global rate of warming, are generally similar in high-end and 'non-high-end' simulations. The exception is the higher latitudes, where land areas warm relatively faster in boreal summer in high-end models, but sea ice areas show varying differences in boreal winter. Many continental interiors warm approximately twice as fast as the global average, with this being particularly accentuated in boreal summer, and the winter-time Arctic Ocean temperatures rise more than three times faster than the global average. Large temperature increases and precipitation decreases are projected in some of the regions that currently experience water resource pressures, including Mediterranean fringe regions, indicating enhanced pressure on water resources in these areas. PMID:21115514
Genomic regions associated with kyphosis in swine
Technology Transfer Automated Retrieval System (TEKTRAN)
Background: A back curvature defect similar to kyphosis in humans has been observed in swine herds. The defect ranges from mild to severe curvature of the thoracic vertebrate in split carcasses and has an estimated heritability of 0.3. The objective of this study was to identify genomic regions that...
Effect of curvature on the backscattering from leaves
NASA Technical Reports Server (NTRS)
Sarabandi, K.; Senior, T. B. A.; Ulaby, F. T.
1988-01-01
Using a model previously developed for the backscattering cross section of a planar leaf at X-band frequencies and above, the effect of leaf curvature is examined. For normal incidence on a rectangular section of a leaf curved in one and two dimensions, an integral expression for the backscattered field is evaluated numerically and by a stationary phase approximation, leading to a simple analytical expression for the cross section reduction produced by the curvature. Numerical results based on the two methods are virtually identical, and in excellent agreement with measured data for rectangular sections of coleus leaves applied to the surfaces of styrofoam cylinders and spheres of different radii.
Effect of curvature on the backscattering from a leaf
NASA Technical Reports Server (NTRS)
Sarabandi, K.; Senior, T. B. A.; Ulaby, F. T.
1988-01-01
Using a model previously developed for the backscattering cross section of a planar leaf at X-band frequencies and above, the effect of leaf curvature is examined. For normal incidence on a rectangular section of a leaf curved in one and two dimensions, an integral expression for the backscattered field is evaluated numerically and by a stationary phase approximation, leading to a simple analytical expression for the cross-section reduction produced by the curvature. Numerical results based on the two methods are virtually identical, and in excellent agreement with measured data for rectangular sections of coleus leaves applied to the surfaces of styrofoam cylinders and spheres of different radii.
Electron energy transport and magnetic curvature driven modes
Coppi, B.; Tang, W.M.
1984-10-01
A transport coefficient for anomalous electron thermal conduction is constructed on the basis of the so-called Principle of Profile Consistency. It is assumed that the relevant modes in plasma where a substantial fraction of the electron population is magnetically trapped produce magnetic reconnection at a microscopic level and are driven by the combined effects of the plasma pressure gradient and the magnetic field curvature. Consequently, the scaling for the electron energy confinement time exhibits a strongly favorable dependence on the radius of magnetic curvature.
Constant curvature solutions of Grassmannian sigma models: (1) Holomorphic solutions
NASA Astrophysics Data System (ADS)
Delisle, L.; Hussin, V.; Zakrzewski, W. J.
2013-04-01
We present a general procedure for constructing constant curvature holomorphic maps of 2-spheres into Grassmannian manifolds G(m,n). Our procedure allows us to make a couple of conjectures as to the possible values of this curvature. We prove our conjectures for G(2,4), G(2,5), present explicit formulae for the relevant maps and show that they agree with those found by other methods. We also make some comments about the maps into G(2,n) for n≥6.
Focal Length Controllable Ultrasonic Array Transducer with Adjustable Curvature
NASA Astrophysics Data System (ADS)
Kim, Jungsoon; Kim, Moojoon; Ha, Kanglyel
2012-07-01
In the underwater imaging field, the control of the focal length of a transducer is very useful. As one of the control methods, we suggested an ultrasonic array transducer with adjustable curvature by using air pressure. The curvature of the transducer was investigated according to the air pressure level in the back space of the transducer. Concave-, planar-, and convex-type transducers were obtained with different air pressure levels. The acoustic fields of the transducer were measured for different shapes of the radiation surface.
HIGH-RESOLUTION SEISMIC VELOCITY AND ATTENUATION MODELS OF THE CAUCASUS-CASPIAN REGION
Mellors, R; Gok, R; Sandvol, E
2007-07-10
The southwest edge of Eurasia is a tectonically and structurally complex region that includes the Caspian and Black Sea basins, the Caucasus Mountains, and the high plateaus south of the Caucasus. Crustal and upper mantle velocities show great heterogeneity in this region and regional phases display variations in both amplitudes and travel time. Furthermore, due to a lack of quality data, the region has largely been unexplored in terms of the detailed lithospheric seismic structure. A unified high-resolution 3D velocity and attenuation model of the crust and upper mantle will be developed and calibrated. This model will use new data from 23 new broadband stations in the region analyzed with a comprehensive set of techniques. Velocity models of the crust and upper mantle will be developed using a joint inversion of receiver functions and surface waves. The surface wave modeling will use both event-based methods and ambient noise tomography. Regional phase (Pg, Pn, Sn, and Lg) Q model(s) will be constructed using the new data in combination with existing data sets. The results of the analysis (both attenuation and velocity modeling) will be validated using modeling of regional phases, calibration with selected events, and comparison with previous work. Preliminary analyses of receiver functions show considerable variability across the region. All results will be integrated into the KnowledgeBase.
Barone, William R.; Amini, Rouzbeh; Maiti, Spandan; Moalli, Pamela A.; Abramowitch, Steven D.
2015-01-01
Exposure following pelvic organ prolapse repair has been observationally associated with wrinkling of the implanted mesh. The purpose of this study was to quantify the impact of variable boundary conditions on the out-of-plane deformations of mesh subjected to tensile loading. Using photogrammetry and surface curvature analyses, deformed geometries were accessed for two commercially available products. Relative to standard clamping methods, the amount of out-of-plane deformation significantly increased when point loads were introduced to simulate suture fixation in-vivo. These data support the hypothesis that regional increases in the concentration of mesh potentially enhance the host’s foreign body response, leading to exposure. PMID:25843260
NASA Technical Reports Server (NTRS)
Bagshaw, S. L.; Cleland, R. E.
1990-01-01
Gravitropic curvature results from unequal growth rates on the upper and lower sides of horizontal stems. These unequal growth rates could be due to differences in wall extensibility between the two sides. To test this, the time course of curvature of horizontal sunflower (Helianthus annuus L.) hypocotyls was determined and compared with the time courses of changes in Instron-measured wall extensibility (PEx) of the upper and lower epidermal layers. As gravicurvature developed, so did the difference in PEx between the upper and lower epidermis. The enhanced growth rate on the lower side during the period of maximum increase in curvature was matched by PEx values greater than those of the vertical control, while the inhibited growth rate on the upper side was accompanied by PEx values below that of the control. The close correlation between changes in growth rates and alterations in PEx demonstrates that changes in wall extensibility play a major role in controlling gravicurvature.
REGIONAL AIR POLLUTION STUDY. HIGH VOLUME FILTER MEASUREMENTS OF SUSPENDED PARTICULATE MATTER
Ten of the 25 stations making up the Regional Air Monitoring System were equipped with dichotomous samplers and high volume filter samplers for aerosol measurements. The high volume samplers collected samples every third day for 24-hour periods (0000-2400). Sample filters were re...
Not Available
2006-10-01
This brochure describes the key high-performance building features of the Blackstone Valley High School. The brochure was paid for by the Massachusetts Technology Collaborative as part of their Green Schools Initiative. High-performance features described are daylighting and energy-efficient lighting, indoor air quality, solar energy, building envelope, heating and cooling systems, and water conservation. Energy cost savings are also discussed.
Curvature effects in rapid alloy solidification
NASA Astrophysics Data System (ADS)
Conti, Massimo
2001-04-01
The growth of a cylindrical or spherical crystal into its undercooled melt is a process whose description is complicated by the lack of a stationary regime. A simple approach to the problem, justified for low growth rates and widely used in the past for both pure substances and alloy solidification, is based on a quasistatic approximation which assumes an instantaneous adaptation of the diffusional field to the interface configuration. For alloy solidification, assuming isothermal conditions and local interface equilibrium, this simplified model predicts a diffusion controlled growth, with the radius of the crystal increasing asymptotically as ~t1/2. However, as pointed out by recent investigations, thermal diffusion and nonequilibrium effects enter as essential ingredients in rapid alloy solidification. In the present paper we use the phase-field model to simulate the cylindrical and spherical growth of a solid germ into a supersaturated alloy melt. The problem is treated in its full time-dependent characteristics, accounting for nonequilibrium effects as well as for the rejection of both heat and solute away from the advancing front. We observe a complex behavior and a rich variety of dynamic regimes: in different regions of parameter space the growth rate is limited by diffusion (either thermal or chemical) or is kinetic controlled. Traversing the boundaries which limit these regions, the process undergoes sharp transitions which leave a trace in the solidified alloy. For realistic values of the Lewis number, thermal effects drive the process into a a diffusive regime, in which the rate limiting mechanism is the rejection of solute.
Tests and evaluation of a variable focus liquid lens for curvature wavefront sensors in astronomy.
Fuentes-Fernández, Jorge; Cuevas, Salvador; Álvarez-Nuñez, Luis C; Watson, Alan
2013-10-20
Curvature wavefront sensors (WFSs), which obtain the wavefront aberrations from two defocused intensity images at each side of the pupil plane, have shown to be highly efficient for astronomical applications. We propose here an alternative defocusing mechanism for curvature sensors, based on an electrowetting-based variable focus liquid lens. Typically, the sampling rates of a WFS for active optics are of the order of 0.01 Hz, and the focus modulation can be done by simply moving the detector back and forth. On the other hand, adaptive optics may require speeds of up to several hundred hertz, and the modulation is then done by using a fast vibrating membrane mirror. We believe variable focus liquid lenses may be able to perform this focus modulation, reducing the overall size of the system and without the need of extra moving parts. We have done a full characterization of the Varioptic Arctic 416 liquid lens, and we have evaluated its potential performance in different curvature configurations. PMID:24216579
Curvature induced by amyloplast magnetophoresis in protonemata of the moss Ceratodon purpureus
NASA Technical Reports Server (NTRS)
Kuznetsov, O. A.; Schwuchow, J.; Sack, F. D.; Hasenstein, K. H.
1999-01-01
After gravistimulation of Ceratodon purpureus (Hedw.) Brid. protonemata in the dark, amyloplast sedimentation was followed by upward curvature in the wild-type (WT) and downward curvature in the wwr mutant (wrong way response). We used ponderomotive forces induced by high-gradient magnetic fields (HGMF) to simulate the effect of gravity and displace the presumptive statoliths. The field was applied by placing protonemata either between two permanent magnets at the edge of the gap, close to the edge of a magnetized ferromagnetic wedge, or close to a small (<1 mm) permanent magnet. Continuous application of an HGMF in all three configurations resulted in plastid displacement and induced curvature in tip cells of WT and wwr protonemata. WT cells curved toward the HGMF, and wwr cells curved away from the HGMF, comparable to gravitropism. Plastids isolated from protonemal cultures had densities ranging from 1.24 to 1.38 g cm-3. Plastid density was similar for both genotypes, but the mutant contained larger plastids than the WT. The size difference might explain the stronger response of the wwr protonemata to the HGMF. Our data support the plastid-based theory of gravitropic sensing and suggest that HGMF-induced ponderomotive forces can substitute for gravity.
Curvature induced by amyloplast magnetophoresis in protonemata of the moss Ceratodon purpureus.
Kuznetsov, O A; Schwuchow, J; Sack, F D; Hasenstein, K H
1999-02-01
After gravistimulation of Ceratodon purpureus (Hedw.) Brid. protonemata in the dark, amyloplast sedimentation was followed by upward curvature in the wild-type (WT) and downward curvature in the wwr mutant (wrong way response). We used ponderomotive forces induced by high-gradient magnetic fields (HGMF) to simulate the effect of gravity and displace the presumptive statoliths. The field was applied by placing protonemata either between two permanent magnets at the edge of the gap, close to the edge of a magnetized ferromagnetic wedge, or close to a small (<1 mm) permanent magnet. Continuous application of an HGMF in all three configurations resulted in plastid displacement and induced curvature in tip cells of WT and wwr protonemata. WT cells curved toward the HGMF, and wwr cells curved away from the HGMF, comparable to gravitropism. Plastids isolated from protonemal cultures had densities ranging from 1.24 to 1.38 g cm-3. Plastid density was similar for both genotypes, but the mutant contained larger plastids than the WT. The size difference might explain the stronger response of the wwr protonemata to the HGMF. Our data support the plastid-based theory of gravitropic sensing and suggest that HGMF-induced ponderomotive forces can substitute for gravity. PMID:9952461
NASA Astrophysics Data System (ADS)
Joe, Anton; Dadhich, Naresh; Singh, Parampreet
2015-04-01
The loop quantum dynamics of Kantowski-Sachs and the interior of higher genus black hole spacetimes with cosmological constant has some peculiar features not shared by various other spacetimes in loop quantum cosmolgy. As in the other cases, though the quantum geometric effects resolve the singularity and result in a bounce, after the bounce a spacetime with small spacetime curvature does not emerge at late times. Instead, asymptotically the spacetime has constant spacetime curvature with a product manifold. Interestingly, though the spacetime curvature of these asymptotic spacetimes is very high, the effective metric of these spacetimes is a solution to the Einstein field equations. Analysis of the components of the Ricci tensor shows that after the singularity resolution, the Kantowski-Sachs spacetimes lead to an effective charged Nariai, and, the higher genus black hole interior lead to an anti Bertotti-Robinson spacetime with an effective tachyonic charge. The asymptotic spacetimes have an effective cosmological constant which is different in magnitude, and sometimes even its sign, from the cosmological constant in the Kantwoski-Sachs and higher genus black hole metrics.
Set-size effects in simple visual search for contour curvature.
Sakai, Koji; Morishita, Masanao; Matsumoto, Hirofumi
2007-01-01
In a visual-search paradigm, both perception and decision processes contribute to the set-size effects. Using yes - no search tasks in set sizes from 2 to 8 for contour curvature, we examined whether the set-size effects are predicted by either the limited-capacity model or the decision-noise model. There are limitations in perception and decision-making in the limited-capacity model, but only in decision-making in the decision-noise model. The results of four experiments showed that the slopes of the logarithm of threshold plotted against the logarithm of set size ranged from 0.24 to 0.32, when the curvature was high or low, contour convexity was upward or downward, and stimulus was masked or unmasked. These slopes were closer to the prediction of 0.23 by the decision-noise model than that of 0.73 by the limited-capacity model. We interpret this that in simple visual search for contour curvature, the decision noise mainly affects the set-size effects and perceptual capacity is not limited. PMID:17455749
Kapnisis, Konstantinos K; Halwani, Dina O; Brott, Brigitta C; Anderson, Peter G; Lemons, Jack E; Anayiotos, Andreas S
2013-04-01
Preliminary studies have revealed that some stents undergo corrosion and fatigue-induced fracture in vivo, with significant release of metallic ions into surrounding tissues. A direct link between corrosion and in-stent restenosis has not been clearly established; nonetheless in vitro studies have shown that relatively high concentrations of heavy metal ions can stimulate both inflammatory and fibrotic reactions, which are the main steps in the process of restenosis. To isolate the mechanical effects from the local biochemical effects, accelerated biomechanical testing was performed on single and overlapping Nickel-Titanium (NiTi) stents subjected to various degrees of curvature. Post testing, stents were evaluated using Scanning Electron Microscopy (SEM) to identify the type of surface alterations. Fretting wear was observed in overlapping cases, in both straight and curved configurations. Stent strut fractures occurred in the presence of geometric curvature. Fretting wear and fatigue fractures observed on stents following mechanical simulation were similar to those from previously reported human stent explants. It has been shown that biomechanical factors such as arterial curvature combined with stent overlapping enhance the incidence and degree of wear and fatigue fracture when compared to single stents in a straight tube configuration. PMID:23313643
NASA Astrophysics Data System (ADS)
Lee, Sin-Doo
2015-10-01
Soft matters such as liquid crystals and biological molecules exhibit a variety of interesting physical phenomena as well as new applications. Recently, in mimicking biological systems that have the ability to sense, regulate, grow, react, and regenerate in a highly responsive and self-adaptive manner, the significance of the liquid crystal order in living organisms, for example, a biological membrane possessing the lamellar order, is widely recognized from the viewpoints of physics and chemistry of interfaces and membrane biophysics. Lipid bilayers, resembling cell membranes, provide primary functions for the transport of biological components of ions and molecules in various cellular activities, including vesicle budding and membrane fusion, through lateral organization of the membrane components such as proteins. In this lecture, I will describe how the liquid crystal-analog curvature elasticity of a lipid bilayer plays a critical role in developing a new platform for understanding diverse biological functions at a cellular level. The key concept is to manipulate the local curvature at an interface between a solid substrate and a model membrane. Two representative examples will be demonstrated: one of them is the topographic control of lipid rafts in a combinatorial array where the ligand-receptor binding event occurs and the other concerns the reconstitution of a ring-type lipid raft in bud-mimicking architecture within the framework of the curvature elasticity.
IRSp53 senses negative membrane curvature and phase separates along membrane tubules
Prévost, Coline; Zhao, Hongxia; Manzi, John; Lemichez, Emmanuel; Lappalainen, Pekka; Callan-Jones, Andrew; Bassereau, Patricia
2015-01-01
BAR domain proteins contribute to membrane deformation in diverse cellular processes. The inverted-BAR (I-BAR) protein IRSp53, for instance, is found on the inner leaflet of the tubular membrane of filopodia; however its role in the formation of these structures is incompletely understood. Here we develop an original assay in which proteins are encapsulated in giant unilamellar vesicles connected to membrane nanotubes. Our results demonstrate that I-BAR dimers sense negative membrane curvature. Experiment and theory reveal that the I-BAR displays a non-monotonic sorting with curvature, and expands the tube at high imposed tension while constricting it at low tension. Strikingly, at low protein density and tension, protein-rich domains appear along the tube. This peculiar behaviour is due to the shallow intrinsic curvature of I-BAR dimers. It allows constriction of weakly curved membranes coupled to local protein enrichment at biologically relevant conditions. This might explain how IRSp53 contributes in vivo to the initiation of filopodia. PMID:26469246
Curvatures with uncertainties derived in conformal space to characterize tendon microstructure.
Harvey, Ann K; Szilagyi, Tunde; Brady, Michael; Thompson, Mark S; Joshi, Niranjan
2010-01-01
There is a growing demand for non-invasive methods to diagnose tendon injuries and monitor the healing processes of their repair. To date there is limited knowledge on their structure and function and the interlink between these. One of the potential targets in this investigation is the extracellular matrix (ECM) that captures its structural changes. Recently we reported on the assessment tendon damage on a macroscopic level from high field MR signals. In this paper, we present a methodology that enables structural description on a microscopic level. We derived curvature values from the conformal monogenic signal, which however can become unreliable in the presence of noise. To account for this we use non parametric noise properties and a 1D feature based uncertainty measure in an iterative framework using Hidden Markov Measure Field (HMMF). The proposed method reveals that curvature values derived from normal tendon tissue microscopy images are higher and more homogenous than curvature values derived from the damaged tendon images. PMID:21096485
Controlling carbon-nanotube-phospholipid solubility by curvature-dependent self-assembly.
Määttä, Jukka; Vierros, Sampsa; Sammalkorpi, Maria
2015-03-12
Control of aqueous dispersion is central in the processing and usage of nanoscale hydrophobic objects. However, selecting dispersive agents based on the size and form of the hydrophobic object and the role of coating morphology in dispersion efficiency remain important open questions. Here, the effect of the substrate and the dispersing molecule curvature, as well as, the influence of dispersant concentration on the adsorption morphology are examined by molecular simulations of graphene and carbon nanotube (CNT) substrates with phospholipids of varying curvature as the dispersing agents. Lipid spontaneous curvature is increased from close to zero (effectively cylindrical lipid) to highly positive (effectively conical lipid) by studying double tailed dipalmitoylphosphadidylcholine (DPPC) and single tailed lysophosphadidylcholine (LPC) which differ in the number of acyl chains but have identical headgroup. We find that lipids are good dispersion agents for both planar and curved nanoparticles and induce a dispersive barrier nonsize selectively. Differences in dispersion efficiency arise from lipid headgroup density and their extension from the hydrophobic substrate in the adsorption morphology. We map the packing morphology contributing factors and report that the aggregate morphologies depend on the competition of interactions rising from (1) hydrophobicity driven maximization of lipid-substrate contacts and lipid self-adhesion, (2) tail bending energy cost, (3) preferential alignment along the graphitic substrate principal axes, and (4) lipid headgroup preferential packing. Curved substrates adjust the morphology by changing the balance between the interaction strengths. Jointly, the findings show substrate curvature and dimensions are a way to tune lipid adsorption to desired, self-assembling patterns. Besides engineering dispersion efficiency, the findings could bear significance in designing materials with defined molecular scale, molecular coatings for
Yu, Ying; Lv, Nan; Wang, Shengzhang; Karmonik, Christof; Liu, Jian-Min; Huang, Qinghai
2015-01-01
Purpose Flow diverters (FD) are increasingly being considered for treating large or giant wide-neck aneurysms. Clinical outcome is highly variable and depends on the type of aneurysm, the flow diverting device and treatment strategies. The objective of this study was to analyze the effect of different flow diverting strategies together with parent artery curvature variations on altering intra-aneurysmal hemodynamics. Methods Four ideal intracranial aneurysm models with different parent artery curvature were constructed. Computational fluid dynamics (CFD) simulations of the hemodynamics before and after applying five types of flow diverting strategies (single FD, single FD with 5% and 10% packing density of coils, two FDs with 25% and 50% overlapping rate) were performed. Changes in pressure, wall shear stress (WSS), relative residence time (RRT), inflow velocity and inflow volume rate were calculated and compared. Results Each flow diverting strategy resulted in enhancement of RRT and reduction of normalized mean WSS, inflow volume rate and inflow velocity in various levels. Among them, 50% overlapped FD induced most effective hemodynamic changes in RRT and inflow volume rate. The mean pressure only slightly decreased after treatment. Regardless of the kind of implantation of FD, the mean pressure, inflow volume rate and inflow velocity increased and the RRT decreased as the curvature of the parent artery increased. Conclusions Of all flow diverting strategies, overlapping FDs induced most favorable hemodynamic changes. Hemodynamics alterations post treatment were substantially influenced by parent artery curvature. Our results indicate the need of an individualized flow diverting strategy that is tailored for a specific aneurysm. PMID:26398847
Surface roughness of rock faces through the curvature of triangulated meshes
NASA Astrophysics Data System (ADS)
Lai, P.; Samson, C.; Bose, P.
2014-09-01
In this paper, we examine three different measures of roughness based on a geometric property of surfaces known as curvature. These methods were demonstrated using an image of a large rock face made up of a smooth blocky limestone in contact with a rough friable dolostone. The point cloud analysed contained 10,334,288 points and was acquired at a distance of 3 m from the rock face. The point cloud was first decimated using an epsilon-net and then meshed using the Poisson surface reconstruction method before the proposed measures of roughness were applied. The first measure of roughness is defined as the difference in curvature between a mesh and a smoothed version of the same mesh. The second measure of roughness is a voting system applied to each vertex which identifies the subset of vertices which represent rough regions within the mesh. The third measure of roughness uses a combination of spatial partitioning data structures and data clustering in order to define roughness for a region in the mesh. The spatial partitioning data structure allows for a hierarchy of roughness values which is related to the size of the region being considered. All of the proposed measures of roughness are visualised using colour-coded displays which allows for an intuitive interpretation.
Posterior corneal curvature changes following Refractive Small Incision Lenticule Extraction
Ganesh, Sri; Patel, Utsav; Brar, Sheetal
2015-01-01
Purpose To compare the posterior corneal curvature changes, in terms of corneal power and asphercity, following Refractive Small Incision Lenticule Extraction (ReLEx SMILE) procedure for low, moderate, and high myopia. Methods This retrospective, non randomized, comparative, interventional trial; included 52 eyes of 26 patients, divided in three groups: low myopia (myopia ≤3 D [diopters] spherical equivalent [SE]), moderate myopia (myopia >3 D and <6 D SE), and high myopia (myopia ≥6 D SE). All patients were treated for myopia and myopic astigmatism using ReLEx SMILE. The eyes were examined pre-operatively and 3 months post-operatively using SCHWIND SIRIUS, a three-dimensional rotating Scheimpflug camera with a Placido disc topographer to assess corneal changes with regard to keratometric power and asphericity of the cornea. Results A statistically significant increase in mean keratometric power in the 3, 5, and 7 mm zones of the posterior corneal surface compared with its pre-ReLEx SMILE value was detected after 3 months in the moderate myopia group (pre-operative [pre-op] −6.14±0.23, post-operative [post-op] −6.29±0.22, P<0.001) and high myopia group (pre-op −6.19±0.16, post-op −6.4±0.18, P<0.001), but there was no significant change in keratometric power of the posterior surface in the low myopia group (pre-op −5.87±0.17, post-op −6.06±0.29, P=0.143). Asphericity (Q-value) of the posterior surface changed significantly (P<0.001) after ReLEx SMILE in the moderate myopia group in the 3, 5, and 7 mm zones, and in the high myopia group in the 3 and 7 mm zones; but there was no significant change in the Q-value in the low myopia group in all three zones (pre-op 0.23±0.43, post-op −0.40±0.71, P=0.170), and in the high myopia group in the 5 mm zone (P=0.228). Conclusion ReLEx SMILE causes significant changes in posterior corneal keratometric power and asphericity in moderate and high myopia, but the effect is subtle and insignificant in low
McCullough, Ian M.; Davis, Frank W.; Dingman, John R.; Flint, Lorraine E.; Flint, Alan L.; Serra-Diaz, Josep M.; Syphard, Alexandra D.; Moritz, Max A.; Hannah, Lee; Franklin, Janet
2016-01-01
In moisture-limited, Mediterranean-climate landscapes, high elevations may experience the greatest exposure to climate change in the 21st century. High elevation species may thus be especially vulnerable to continued climate change as habitats shrink and historically energy-limited locations become increasingly moisture-limited in the future.
Curvature facilitates prey fixation in predatory insect claws.
Petie, Ronald; Muller, Mees
2007-02-21
Insects show a large variety in prey capture strategies, with a correspondingly large diversity in predatory adaptations. We studied a specific type of predatory claws, these can for example be found in praying mantis species. The claw is closeable over its entire length and the prey is fixed between the femur (upper arm) and the tibia (lower arm) of the insect leg. The morphology of these predatory claws is diverse. Some species have straight claws covered with spines, while other species have smooth, curved claws. We have studied the mechanics of this femur-tibia type of predatory insect claws, by making a physical model, eventually trying to explain why in some insect species the claws are curved instead of straight. The main results are (1) when comparing curved claws to straight claws, curvature leads to a strong reduction of forces driving the prey away from the pivoting point, thereby reducing the need for friction generating structures. (2) In the curved claw model a position exists where the resulting force on the prey is exactly zero. This is because the normal forces on the femur and tibia are opposed, and in line. At this position the prey is perfectly clamped and not driven out of the claw. This feature does not exist in straight claws. (3) In the curved claw, the prey cannot be placed at a position further than a certain maximum distance from the pivoting point. Near this maximum position, the resulting force on the prey reaches high values because moment arms are near zero. (4) Between the zero position and the maximum position the resulting force is directed toward the pivoting point, which stabilizes prey fixation. PMID:17056069
Controlling Protein Oligomerization with Surface Curvature on the Nanoscale
NASA Astrophysics Data System (ADS)
Kurylowicz, Marty; Dutcher, John
2011-03-01
We investigate the effect of surface curvature on the conformation of beta-lactoglobulin (β LG) using Single Molecule Force Spectroscopy. β LG is a model interfacial protein which stabilizes oil droplets in milk and is known to undergo structural rearrangement when adsorbed onto a surface. We reliably control nanoscale surface curvature by creating close-packed monolayers of monodisperse polystyrene (PS) nanoparticles with diameters of 20, 40, 60, 80 and 140 nm, which are stable in aqueous buffer. By adsorbing β LG onto these hydrophobic surfaces and collecting force-extension curves in the fluid phase we can compare the conformation of β LG on 5 different surface curvatures with that on a flat PS film. We demonstrate a transition from oligomeric to monomeric β LG as the surface curvature is increased. Histograms of contour length from fits to peaks in the force-extension curves show a single maximum near 30 nm for β LG adsorbed onto nanoparticles with diameters less than 80 nm. For the larger nanoparticles, the histogram approaches that observed for β LG adsorbed onto a flat PS film, with maxima indicative of β LG dimers and trimers.
Stiffness, not inertial coupling, determines path curvature of wrist motions.
Charles, Steven K; Hogan, Neville
2012-02-01
When humans rotate their wrist in flexion-extension, radial-ulnar deviation, and combinations, the resulting paths (like the path of a laser pointer on a screen) exhibit a distinctive pattern of curvature. In this report we show that the passive stiffness of the wrist is sufficient to account for this pattern. Simulating the dynamics of wrist rotations using a demonstrably realistic model under a variety of conditions, we show that wrist stiffness can explain all characteristics of the observed pattern of curvature. We also provide evidence against other possible causes. We further demonstrate that the phenomenon is robust against variations in human wrist parameters (inertia, damping, and stiffness) and choice of model inputs. Our findings explain two previously observed phenomena: why faster wrist rotations exhibit more curvature and why path curvature rotates with pronation-supination of the forearm. Our results imply that, as in reaching, path straightness is a goal in the planning and control of wrist rotations. This requires humans to predict and compensate for wrist dynamics, but, unlike reaching, nonlinear inertial coupling (e.g., Coriolis acceleration) is insignificant. The dominant term to be compensated is wrist stiffness. PMID:22131378
Effect of asymmetric auxin application on Helianthus hypocotyl curvature
NASA Technical Reports Server (NTRS)
Migliaccio, F.; Rayle, D. L.
1989-01-01
Indole-3-acetic acid was applied asymmetrically to the hypocotyls of sunflower (Helianthus annuus L.) seedlings. After 5 hours on a clinostat, auxin gradients as small as 1 to 1.3 produced substantial (more than 60 degrees) hypocotyl curvature. This result suggests the asymmetric growth underlying hypocotyl gravitropism can be explained by lateral auxin redistribution.
Wormhole geometries supported by a nonminimal curvature-matter coupling
Garcia, Nadiezhda Montelongo; Lobo, Francisco S. N.
2010-11-15
Wormhole geometries in curvature-matter coupled modified gravity are explored, by considering an explicit nonminimal coupling between an arbitrary function of the scalar curvature, R, and the Lagrangian density of matter. It is the effective stress-energy tensor containing the coupling between matter and the higher order curvature derivatives that is responsible for the null energy condition violation, and consequently for supporting the respective wormhole geometries. The general restrictions imposed by the null energy condition violation are presented in the presence of a nonminimal R-matter coupling. Furthermore, obtaining exact solutions to the gravitational field equations is extremely difficult due to the nonlinearity of the equations, although the problem is mathematically well defined. Thus, we outline several approaches for finding wormhole solutions, and deduce an exact solution by considering a linear R nonmiminal curvature-matter coupling and by considering an explicit monotonically decreasing function for the energy density. Although it is difficult to find exact solutions of matter threading the wormhole satisfying the energy conditions at the throat, an exact solution is found where the nonminimal coupling does indeed minimize the violation of the null energy condition of normal matter at the throat.
Special-holonomy manifolds and quartic-curvature string corrections
NASA Astrophysics Data System (ADS)
Stelle, K. S.
2004-06-01
The quartic-curvature corrections derived from string theory have a very specific impact on the geometry of target-space manifolds of special holonomy. In the cases of Calabi-Yau manifolds and D = 7 manifolds of G2 holonomy, we show how the corrections conspire to preserve the unbroken supersymmetry of these backgrounds.
On a modified streamline curvature method for the Euler equations
NASA Technical Reports Server (NTRS)
Cordova, Jeffrey Q.; Pearson, Carl E.
1988-01-01
A modification of the streamline curvature method leads to a quasilinear second-order partial differential equation for the streamline coordinate function. The existence of a stream function is not required. The method is applied to subsonic and supersonic nozzle flow, and to axially symmetric flow with swirl. For many situations, the associated numerical method is both fast and accurate.
The influence of curvature on film cooling performance
NASA Astrophysics Data System (ADS)
Schwarz, S. G.; Goldstein, R. J.; Eckert, E. R. G.
1990-06-01
The effects of injection rate and strength of curvature on film cooling performance of gas injected through a row of holes on a convex surface is studied. Comparisons are made to film cooling of concave and flat surfaces. Three different relative strengths of curvature (ratio of radius of curvature to radius of injection hole), two density ratios (0.95 and 2.0), and a wide range of blowing rates (0.3 to 2.7) are considered. A foreign gas injection technique (mass transfer analogy) is used. The strength of curvature was controlled by varying the injection hole diameter. At low blowing rates, film cooling is more effective on the convex surface than on a flat or a concave surface. The cross stream pressure gradient present in curved flows tends to push the jet into the convex wall. As the injection rate is increased, normal and tangential jet momentum promote lift-off from the convex surface, thereby lowering performance. In contrast, previous studies show that a concave surface, tangential jet momentum, flow instabilities, and blockage improve performance on a concave surface as blowing rate is increased.
Frustration and curvature - Glasses and the cholesteric blue phase
NASA Technical Reports Server (NTRS)
Sethna, J. P.
1983-01-01
An analogy is drawn between continuum elastic theories of the blue phase of cholesteric liquid crystals and recent theories of frustration in configurational glasses. Both involve the introduction of a lattice of disclination lines to relieve frustration; the frustration is due to an intrinsic curvature in the natural form of parallel transport. A continuum theory of configurational glasses is proposed.
Equilibrium Models of Coronal Loops That Involve Curvature and Buoyancy
NASA Astrophysics Data System (ADS)
Hindman, Bradley W.; Jain, Rekha
2013-12-01
We construct magnetostatic models of coronal loops in which the thermodynamics of the loop is fully consistent with the shape and geometry of the loop. This is achieved by treating the loop as a thin, compact, magnetic fibril that is a small departure from a force-free state. The density along the loop is related to the loop's curvature by requiring that the Lorentz force arising from this deviation is balanced by buoyancy. This equilibrium, coupled with hydrostatic balance and the ideal gas law, then connects the temperature of the loop with the curvature of the loop without resorting to a detailed treatment of heating and cooling. We present two example solutions: one with a spatially invariant magnetic Bond number (the dimensionless ratio of buoyancy to Lorentz forces) and the other with a constant radius of the curvature of the loop's axis. We find that the density and temperature profiles are quite sensitive to curvature variations along the loop, even for loops with similar aspect ratios.
Equilibrium models of coronal loops that involve curvature and buoyancy
Hindman, Bradley W.; Jain, Rekha
2013-12-01
We construct magnetostatic models of coronal loops in which the thermodynamics of the loop is fully consistent with the shape and geometry of the loop. This is achieved by treating the loop as a thin, compact, magnetic fibril that is a small departure from a force-free state. The density along the loop is related to the loop's curvature by requiring that the Lorentz force arising from this deviation is balanced by buoyancy. This equilibrium, coupled with hydrostatic balance and the ideal gas law, then connects the temperature of the loop with the curvature of the loop without resorting to a detailed treatment of heating and cooling. We present two example solutions: one with a spatially invariant magnetic Bond number (the dimensionless ratio of buoyancy to Lorentz forces) and the other with a constant radius of the curvature of the loop's axis. We find that the density and temperature profiles are quite sensitive to curvature variations along the loop, even for loops with similar aspect ratios.
Simple partitions of a hyperbolic plane of positive curvature
Romakina, Lyudmila N
2012-09-30
We construct special monohedral isotropic partitions with symmetries of the hyperbolic plane H of positive curvature with a simple 4-contour as a cell. An analogue of mosaic in these partitions called a tiling is introduced. Also we consider some fractal tilings. The existence of band tilings in each homological series with code (m, n) is proved. Bibliography: 14 titles.
The flow curvature method applied to canard explosion
NASA Astrophysics Data System (ADS)
Ginoux, Jean-Marc; Llibre, Jaume
2011-11-01
The aim of this work is to establish that the bifurcation parameter value leading to a canard explosion in dimension 2 obtained by the so-called geometric singular perturbation method can be found according to the flow curvature method. This result will be then exemplified with the classical Van der Pol oscillator.
A novel high-performance SOI MESFET by stopping the depletion region extension
NASA Astrophysics Data System (ADS)
Orouji, Ali A.; Ramezani, Zeinab; Heydari, Akram Anbar
2014-11-01
A novel power SOI-MESFET is proposed which consists of an insulator region in the channel for high-power applications. The key idea in this work is to stop the depletion region extension toward the drain and source regions and eliminate the gate adjacent spaces. We called the proposed structure as stopped depletion region extension SOI (SDR-SOI) MESFET. The breakdown voltage (VBR) and small-signal characteristics of the proposed structure improve due to the high critical electric field of the insulator region and less extended depletion region. The optimized results show that the VBR of the SDR-SOI MESFET is 45% larger than that obtained for the conventional SOI MESFET (C-MESFET). Furthermore the maximum output power density of the SDR-SOI MESFET is 0.33 W/mm compared with 0.24 W/mm of the C-MESFET. Meanwhile the elimination of the gate depletion layer extension to source/drain leads to decrease gate-drain capacitance (CGD). So, the proposed structure presents the potential for high-power applications.
Attenuation of High Frequency P and S Waves in the Gujarat Region, India
NASA Astrophysics Data System (ADS)
Chopra, Sumer; Kumar, Dinesh; Rastogi, B. K.
2011-05-01
The local earthquake waveforms recorded on broadband seismograph network of Institute of Seismological Research in Gujarat, India have been analyzed to understand the attenuation of high frequency (2-25 Hz) P and S waves in the region. The frequency dependent relationships for quality factors for P ( Q P) and S ( Q S) waves have been obtained using the spectral ratio method for three regions namely, Kachchh, Saurashtra and Mainland Gujarat. The earthquakes recorded at nine stations of Kachchh, five stations of Saurashtra and one station in mainland Gujarat have been used for this analysis. The estimated relations for average Q P and Q S are: Q P = (105 ± 2) f 0.82 ± 0.01, Q S = (74 ± 2) f 1.06 ± 0.01 for Kachchh region; Q P = (148 ± 2) f 0.92 ± 0.01, Q S = (149 ± 14) f 1.43 ± 0.05 for Saurashtra region and Q P = (163 ± 7) f 0.77 ± 0.03, Q S = (118 ± 34) f 0.65 ± 0.14 for mainland Gujarat region. The low Q (<200) and high exponent of f (>0.5) as obtained from present analysis indicate the predominant seismic activities in the region. The lowest Q values obtained for the Kachchh region implies that the area is relatively more attenuative and heterogeneous than other two regions. A comparison between Q S estimated in this study and coda Q ( Qc) previously reported by others for Kachchh region shows that Q C > Q S for the frequency range of interest showing the enrichment of coda waves and the importance of scattering attenuation to the attenuation of S waves in the Kachchh region infested with faults and fractures. The Q S/ Q P ratio is found to be less than 1 for Kachchh and Mainland Gujarat regions and close to unity for Saurashtra region. This reflects the difference in the geological composition of rocks in the regions. The frequency dependent relations developed in this study could be used for the estimation of earthquake source parameters as well as for simulating the strong earthquake ground motions in the region.
LIU, Mingming; CAO, Shinuo; VUDRIKO, Patrick; SUZUKI, Hiroshi; SOMA, Takehisa; XUAN, Xuenan
2016-01-01
Babesia gibsoni is a tick-borne apicomplexan parasite of dogs that often causes fever and hemolytic anemia with highly variable clinical outcome. In this study, we sequenced the 254bp Internal Transcribed Spacer 1 region (ITS1) of 54 B. gibsoni isolates from 14 different geographical regions of Japan. The 54 isolates shared high sequence identity with each other and with B. gibsoni isolates reported in GenBank database (97.2–100%). Consistent with previous reports, phylogenetic analysis showed that B. gibsoni isolates from Japan formed the same clade with those from U.S.A., Australia, India and Taiwan. Our finding indicates that B. gibsoni ITS1 region is highly conserved among isolates from dogs in Japan, making it a useful genetic marker for molecular epidemiology of the parasite. PMID:26806537
Liu, Mingming; Cao, Shinuo; Vudriko, Patrick; Suzuki, Hiroshi; Soma, Takehisa; Xuan, Xuenan
2016-06-01
Babesia gibsoni is a tick-borne apicomplexan parasite of dogs that often causes fever and hemolytic anemia with highly variable clinical outcome. In this study, we sequenced the 254bp Internal Transcribed Spacer 1 region (ITS1) of 54 B. gibsoni isolates from 14 different geographical regions of Japan. The 54 isolates shared high sequence identity with each other and with B. gibsoni isolates reported in GenBank database (97.2-100%). Consistent with previous reports, phylogenetic analysis showed that B. gibsoni isolates from Japan formed the same clade with those from U.S.A., Australia, India and Taiwan. Our finding indicates that B. gibsoni ITS1 region is highly conserved among isolates from dogs in Japan, making it a useful genetic marker for molecular epidemiology of the parasite. PMID:26806537
NASA Technical Reports Server (NTRS)
Ishikawa, H.; Evans, M. L.
1992-01-01
We examined the response of primary roots of maize (Zea mays L. cv Merit) to unilateral application of calcium with particular attention to the site of application, the dependence on growth rate, and possible contributions of thigmotropic stimulation during application. Unilateral application of agar to the root cap induced negative curvature whether or not the agar contained calcium. This apparent thigmotropic response was enhanced by including calcium in the agar. Curvature away from objects applied unilaterally to the extreme root tip occurred both in intact and detipped roots. When agar containing calcium chloride was applied to one side of the postmitotic isodiametric growth zone ( a region between the apical meristem and the elongation zone), the root curved toward the side of application. This response could not be induced by plain agar. We conclude that curvature away from calcium applied to the root tip results from a thigmotropic response to stimulation during application. In contrast, curvature toward the calcium applied to the postmitotic isodiametric growth zone results from direct calcium-induced inhibition of growth.
Bending rigidity and higher-order curvature terms for the hard-sphere fluid near a curved wall.
Urrutia, Ignacio
2014-03-01
In this work I derive analytic expressions for the curvature-dependent fluid-substrate surface tension of a hard-sphere fluid on a hard curved wall. In the first step, the curvature thermodynamic properties are found as truncated power series in the activity in terms of the exactly known second- and third-order cluster integrals of the hard-sphere fluid near spherical and cylindrical walls. These results are then expressed as packing fraction power series and transformed to different reference regions, which is equivalent to considering different positions of the dividing surface. Based on the truncated series it is shown that the bending rigidity of the system is non-null and that higher-order terms in the curvature also exist. In the second step, approximate analytic expressions for the surface tension, the Tolman length, the bending rigidity, and the Gaussian rigidity as functions of the packing fraction are found by considering the known terms of the series expansion complemented with a simple fitting approach. It is found that the obtained formulas accurately describe the curvature thermodynamic properties of the system; further, they are more accurate than any previously published expressions. PMID:24730805
NASA Technical Reports Server (NTRS)
Khurana, J. P.; Best, T. R.; Poff, K. L.
1989-01-01
Phototropic and gravitropic curvature by hypocotyls of Arabidopsis thaliana is minimal when the side of the hook with the cotyledons attached is positioned toward the direction of tropistic curvature, and maximal when that side of the hook is positioned away from the direction of tropistic curvature. Based on these data, it is proposed that the position of the hook with attached cotyledons affects curvature and not stimulus perception. A randomly oriented population of plants exhibited considerable heterogeneity in tropistic curvature. This heterogeneity arises at least in part from the dependence of curvature on the position of the hook.
Parsec-scale X-ray flows in high-mass star-forming regions
NASA Astrophysics Data System (ADS)
Townsley, L. K.; Broos, P. S.; Feigelson, E. D.; Garmire, G. P.
The Chandra X-ray Observatory is providing remarkable new views of massive star-forming regions, revealing all stages in the life cycle of high-mass stars and their effects on their surroundings. We present a Chandra tour of several high-mass star-forming regions, highlighting physical processes that characterize the life of a cluster of high-mass stars, from deeply-embedded cores too young to have established an HII region to superbubbles so large that they shape our views of galaxies. Along the way we see that X-ray observations reveal hundreds of stellar sources powering great HII region complexes, suffused by both hard and soft diffuse X-ray structures caused by fast O-star winds thermalized in wind-wind collisions or by termination shocks against the surrounding media. Finally, we examine the effects of the deaths of high-mass stars that remained close to their birthplaces, exploding as supernovae within the superbubbles that these clusters created. We present new X-ray results on W51 IRS2E and 30 Doradus and we introduce new data on Trumpler 14 in Carina and the W3 HII region complexes W3 Main and W3(OH).
Augmenting Chinese hamster genome assembly by identifying regions of high confidence.
Vishwanathan, Nandita; Bandyopadhyay, Arpan A; Fu, Hsu-Yuan; Sharma, Mohit; Johnson, Kathryn C; Mudge, Joann; Ramaraj, Thiruvarangan; Onsongo, Getiria; Silverstein, Kevin A T; Jacob, Nitya M; Le, Huong; Karypis, George; Hu, Wei-Shou
2016-09-01
Chinese hamster Ovary (CHO) cell lines are the dominant industrial workhorses for therapeutic recombinant protein production. The availability of genome sequence of Chinese hamster and CHO cells will spur further genome and RNA sequencing of producing cell lines. However, the mammalian genomes assembled using shot-gun sequencing data still contain regions of uncertain quality due to assembly errors. Identifying high confidence regions in the assembled genome will facilitate its use for cell engineering and genome engineering. We assembled two independent drafts of Chinese hamster genome by de novo assembly from shotgun sequencing reads and by re-scaffolding and gap-filling the draft genome from NCBI for improved scaffold lengths and gap fractions. We then used the two independent assemblies to identify high confidence regions using two different approaches. First, the two independent assemblies were compared at the sequence level to identify their consensus regions as "high confidence regions" which accounts for at least 78 % of the assembled genome. Further, a genome wide comparison of the Chinese hamster scaffolds with mouse chromosomes revealed scaffolds with large blocks of collinearity, which were also compiled as high-quality scaffolds. Genome scale collinearity was complemented with EST based synteny which also revealed conserved gene order compared to mouse. As cell line sequencing becomes more commonly practiced, the approaches reported here are useful for assessing the quality of assembly and potentially facilitate the engineering of cell lines. PMID:27374913
Stimulation of root elongation and curvature by calcium
NASA Technical Reports Server (NTRS)
Takahashi, H.; Scott, T. K.; Suge, H.
1992-01-01
Ca2+ has been proposed to mediate inhibition of root elongation. However, exogenous Ca2+ at 10 or 20 millimolar, applied directly to the root cap, significantly stimulated root elongation in pea (Pisum sativum L.) and corn (Zea mays L.) seedlings. Furthermore, Ca2+ at 1 to 20 millimolar, applied unilaterally to the caps of Alaska pea roots, caused root curvature away from the Ca2+ source, which was caused by an acceleration of elongation growth on the convex side (Ca2+ side) of the roots. Roots of an agravitropic pea mutant, ageotropum, responded to a greater extent. Roots of Merit and Silver Queen corn also responded to Ca2+ in similar ways but required a higher Ca2+ concentration than that of pea roots. Roots of all other cultivars tested (additional four cultivars of pea and one of corn) curved away from the unilateral Ca2+ source as well. The Ca(2+)-stimulated curvature was substantially enhanced by light. A Ca2+ ionophore, A23187, at 20 micromolar or abscisic acid at 0.1 to 100 micromolar partially substituted for the light effect and enhanced the Ca(2+)-stimulated curvature in the dark. Unilateral application of Ca2+ to the elongation zone of intact roots or to the cut end of detipped roots caused either no curvature or very slight curvature toward the Ca2+. Thus, Ca2+ action on root elongation differs depending on its site of application. The stimulatory action of Ca2+ may involve an elevation of cytoplasmic Ca2+ in root cap cells and may partipate in root tropisms.
Yang, Xunfeng; Li, Lianfa; Wang, Jinfeng; Huang, Jixia; Lu, Shijun
2015-01-01
The objectives of this study were to estimate the effects of temperature on cardiovascular mortality in 26 regions in the south and west of China from 2008 to 2011, and to identify socioeconomic and demographic factors contributing to such inter-region variation in the temperature effect. A separate Poisson generalized additive model (GAM) was fitted to estimate percent changes in cardiovascular mortality at low and high temperatures on a daily basis for each region. The model used the smooth functions to model the nonlinear effects of temperature and humidity and to control for the seasonal factor using the calendar time variable. Given variation in the magnitude of the temperature effect on cardiovascular mortality, we employed a Bayesian network (BN) to identify potential region-specific socioeconomic and demographic factors that may explain the variation. In most regions, an increasing trend in high or low temperature was associated with an increase in cardiovascular mortality, with variation in the magnitude of the temperature effects across regions. Three factors, including per capita years of education (as an indicator of economic status), percentage of the population over 65 years of age and percentage of women had direct impact on cold-related cardiovascular mortality. Number of hospital beds (as an indicator of the availability of medical resources), percentage of population engaged in industrial occupations, and percentage of women showed direct impact on heat-related cardiovascular mortality. Due to the socioeconomic and demographic inequalities between regions, the development of customized prevention and adaptation programs to address the low/high temperatures in vulnerable regions should be prioritized. PMID:26024362
NASA Astrophysics Data System (ADS)
Tarbell, T. D.; Handy, B. N.; Judge, P. G.
1999-05-01
We present TRACE images and movies showing C IV emission (transition region at 80,000 degrees) and UV continuum (temperature minimum region) of quiet and active regions. TRACE images using the 1550, 1600, and 1700 Angstroms filters can be combined to estimate the total emission in the C IV 1548 and 1550 lines and the UV continuum. These are supplemented in different observations with MDI magnetograms, TRACE 171 Angstroms images (Fe IX/X and perhaps O VI), and SUMER spectra of chromospheric and transition region lines from SOHO JOP 72. In quiet sun, bright C IV transients are seen in the vicinity of flux emergence, flux cancellation, and less dramatic interactions of small magnetic structures. Some of these are accompanied by high-velocity explosive events seen in SUMER spectra. The C IV emission can be well-separated from the photospheric magnetic footpoints, suggesting that it takes place on current sheets higher in the atmosphere separating different flux systems. In active regions, both bright and dark fibrils or loops are seen in C IV. Many nano/micro/sub flares are seen, some but not all of which are associated with emerging flux. The C IV emission of "moss" regions, footpoints of hot coronal loops, is contrasted with that of similar plage which does not have hot loops above it. This work was supported by the NASA contracts and grants for TRACE, MDI, and SOHO.
Cool, Geneviève; Lebel, Alexandre; Sadiq, Rehan; Rodriguez, Manuel J
2015-12-01
The regional variability of the probability of occurrence of high total trihalomethane (TTHM) levels was assessed using multilevel logistic regression models that incorporate environmental and infrastructure characteristics. The models were structured in a three-level hierarchical configuration: samples (first level), drinking water utilities (DWUs, second level) and natural regions, an ecological hierarchical division from the Quebec ecological framework of reference (third level). They considered six independent variables: precipitation, temperature, source type, seasons, treatment type and pH. The average probability of TTHM concentrations exceeding the targeted threshold was 18.1%. The probability was influenced by seasons, treatment type, precipitations and temperature. The variance at all levels was significant, showing that the probability of TTHM concentrations exceeding the threshold is most likely to be similar if located within the same DWU and within the same natural region. However, most of the variance initially attributed to natural regions was explained by treatment types and clarified by spatial aggregation on treatment types. Nevertheless, even after controlling for treatment type, there was still significant regional variability of the probability of TTHM concentrations exceeding the threshold. Regional variability was particularly important for DWUs using chlorination alone since they lack the appropriate treatment required to reduce the amount of natural organic matter (NOM) in source water prior to disinfection. Results presented herein could be of interest to authorities in identifying regions with specific needs regarding drinking water quality and for epidemiological studies identifying geographical variations in population exposure to disinfection by-products (DBPs). PMID:26563233
High time resolution observations of HF cross-modulation within the D region ionosphere
NASA Astrophysics Data System (ADS)
Langston, J.; Moore, R. C.
2013-05-01
High-frequency cross-modulation is employed to probe the D region ionosphere during HF heating experiments at the High-frequency Active Auroral Research Program (HAARP) observatory. We have adapted Fejer's well-known cross-modulation probing method to determine the extent of ionospheric conductivity modification in the D region ionosphere with high (5 μsec) time resolution. We demonstrate that the method can be used to analyze D region conductivity changes produced by HF heating both during the initial stages of heating and under steady state conditions. The sequence of CW probe pulses used allow the separation of cross-modulation effects that occur as the probe pulse propagates upward and downward through the heated region. We discuss how this probing technique can be applied to benefit ELF/VLF wave generation experiments and ionospheric irregularities experiments at higher altitudes. We demonstrate that large phase changes equivalent to Doppler shift velocities >60 km/s can be imposed on HF waves propagating through the heated D region ionosphere.
A new curvature compensation technique for CMOS voltage reference using |VGS| and ΔVBE
NASA Astrophysics Data System (ADS)
Xuemin, Li; Mao, Ye; Gongyuan, Zhao; Yun, Zhang; Yiqiang, Zhao
2016-05-01
A new mixed curvature compensation technique for CMOS voltage reference is presented, which resorts to two sub-references with complementary temperature characteristics. The first sub-reference is the source–gate voltage |VGS|p of a PMOS transistor working in the saturated region. The second sub-reference is the weighted sum of gate–source voltages |VGS|n of NMOS transistors in the subthreshold region and the difference between two base–emitter voltages ΔVBE of bipolar junction transistors (BJTs). The voltage reference implemented utilizing the proposed curvature compensation technique exhibits a low temperature coefficient and occupies a small silicon area. The proposed technique was verified in 0.18 μm standard CMOS process technology. The performance of the circuit has been measured. The measured results show a temperature coefficient as low as 12.7 ppm/°C without trimming, over a temperature range from ‑40 to 120 °C, and the current consumption is 50 μA at room temperature. The measured power-supply rejection ratio (PSRR) is ‑31.2 dB @ 100 kHz. The circuit occupies an area of 0.045 mm2. Project supported by the National Natural Science Foundation of China (No. 61376032).
Govindaraju, Kalimuthu; Viswanathan, Girish N; Badruddin, Irfan Anjum; Kamangar, Sarfaraz; Salman Ahmed, N J; Al-Rashed, Abdullah A A A
2016-11-01
This study aims to investigate the influence of artery wall curvature on the anatomical assessment of stenosis severity and to identify a region of misinterpretation in the assessment of per cent area stenosis (AS) for functionally significant stenosis using fractional flow reserve (FFR) as standard. Five artery models of different per cent AS severity (70, 75, 80, 85 and 90%) were considered. For each per cent AS severity, the angle of curvature of the arterial wall varied from straight to an increasingly curved model (0°, 30°, 60°, 90° and 120°). Computational fluid dynamics was performed under transient physiologic hyperemic flow conditions to investigate the influence of artery wall curvature on the pressure drop and the FFR. The findings in this study may be useful in in vitro anatomical assessment of functionally significant stenosis. The FFR decreased with increasing stenosis severity for a given curvature of the artery wall. Moreover, a significant decrease in FFR was found between straight and curved models discussed for a given severity condition. These findings indicate that the curvature effect was included in the FFR assessment in contrast to minimum lumen area (MLA) or per cent AS assessment. The MLA or per cent AS assessment may lead to underestimation of stenosis severity. From this numerical study, an uncertainty region could be evaluated using the clinical FFR cutoff value of 0.8. This value was observed at 81.98 and 79.10% AS for arteries with curvature angles of 0° and 120° respectively. In conclusion, the curvature of the artery should not be neglected in in vitro anatomical assessment. PMID:27052093
Four large-scale field-aligned current systems in the dayside high-latitude region
Ohtani, S.; Potemra, T.A.; Newell, P.T.
1995-01-01
A system of four current sheets of large-scale field-aligned currents (FACs) was discovered in the data set of simultaneous Viking and DMSP-F7 crossings of the dayside high-latitude region. This paper reports four examples of this system that were observed in the prenoon sector. The flow polarities of FACs are upward, downward, upward, and downward, from equatorward to poleward. The lowest-latitude upward current is flowing mostly in the CPS precipitation region, often overlapping with the BPS at its poleward edge, and is interpreted as a region 2 current. The pair of downward and upward FACs in the middle of the structure are collocated with structured electron precipitation. The precipitation of high-energy (>1 keV) electrons is more intense in the lower-latitude downward current sheet. The highest-latitude downward flowing current sheet is located in a weak, low-energy particle precipitation region, suggesting that this current is flowing on open field lines. Simultaneous observations in the postnoon local time sector reveal the standard three-sheet structure of FACs, sometimes described as region 2, region 1, and mantle (referred to the midday region 0) currents. A high correlation was found between the occurrence of the four FAC sheet structure and negative interplanetary magnetic field (IMF) B{sub Y}. The authors discuss the FAC structure in terms of three types of convection cells: the merging, viscous, and lobe cells. During strongly negative IMF B{sub Y}, two convection reversals exist in the prenoon sector; one is inside the viscous cell, and the other is between the viscous cell and the lobe cell. This structure of convection flow is supported by the Viking electric field and auroral UV image data. Based on the convection pattern, the four FAC sheet structure is interpreted as the latitudinal overlap of midday and morning FAC systems. 47 refs., 12 figs., 1 tab.
NASA Astrophysics Data System (ADS)
Nakajima, Y.; Nishikawa, A.; Iguchi, A.; Sakai, K.
2012-12-01
Knowledge of genetic connectivity is useful for understanding of the recovery potential of coral populations after various disturbances, such as coral mass bleaching. Population genetic studies in corals are mostly restricted to Australian and Caribbean species; studies in the northern Pacific are relatively limited. Using microsatellite markers, the population genetics of Acropora sp. 1 was examined between two regions in Japan, the Okinawa-Aka and Bonin Islands, which are separated by approximately 1,500 km of open water in a high-latitude area. Statistically significant but small genetic differentiation in Acropora sp. 1 was detected between and within these regions. Genetic diversity was not obviously reduced in populations of the Bonin Islands, which are relatively isolated. Thus, some level of connectivity appears to be maintained between the two regions, likely because of the high dispersal ability of this broadcast spawner.
NASA Technical Reports Server (NTRS)
Eyre, L. A.
1972-01-01
High altitude color and color infrared photography of the tri-county region of southeast Florida made it feasible to evaluate its potential for quantifying the dimensions of regional change. Attention was focused upon three main aspects of change in the region, which in fact overlap. These were; (1) the transformation of the southeast Florida wetlands; (2) the expansion of agriculture; and (3) the growth of the urbanized area. The development analyzed covered the period of thirteen years from 1956 to 1969. Results using this new 18 km photography were superior because of the degree of resolution, the combined power of color and color infrared interpretation, and the large area covered by each frame. The greatest advantage of high altitude imagery is the time-saving element, since it is possible to delineate and identify major geographic patterns over thousands of sq km very rapidly.
Non-dipole effects on high-order harmonic generation towards the long wavelength region
NASA Astrophysics Data System (ADS)
Zhu, Xiaosong; Wang, Zhe
2016-04-01
The non-dipole (ND) effects on high-order harmonic generation (HHG) with the laser wavelength increasing towards the long wavelength region are investigated. Two major phenomena due to the ND effects, the decrease of the HHG intensity and the shift of the harmonic spectrum, are discussed. It is shown that, for the commonly used laser intensity I∼1014 W/cm2 and target with ionization potential Ip ∼ 0.5 a . u ., the ND effects become nonnegligible when the laser wavelength is increased to the mid-infrared region of several thousand nanometers. It is also found that the variation of the ND effects presents different rules compared with those towards the high intensity region. Two fitting formulas are proposed to describe the variation rules. The physical meanings of the fitting results are discussed with classical calculation.
REGIONAL BINNING FOR CONTINUED STORAGE OF SPENT NUCLEAR FUEL AND HIGH-LEVEL WASTES
W. Lee Poe, Jr
1998-10-01
In the Continued Storage Analysis Report (CSAR) (Reference 1), DOE decided to analyze the environmental consequences of continuing to store the commercial spent nuclear fuel (SNF) at 72 commercial nuclear power sites and DOE-owned spent nuclear fuel and high-level waste at five Department of Energy sites by region rather than by individual site. This analysis assumes that three commercial facilities pairs--Salem and Hope Creek, Fitzpatrick and Nine-Mile Point, and Dresden and Moms--share common storage due to their proximity to each other. The five regions selected for this analysis are shown on Figure 1. Regions 1, 2, and 3 are the same as those used by the Nuclear Regulatory Commission in their regulatory oversight of commercial power reactors. NRC Region 4 was subdivided into two regions to more appropriately define the two different climates that exist in NRC Region 4. A single hypothetical site in each region was assumed to store all the SNF and HLW in that region. Such a site does not exist and has no geographic location but is a mathematical construct for analytical purposes. To ensure that the calculated results for the regional analyses reflect appropriate inventory, facility and material degradation, and radionuclide transport, the waste inventories, engineered barriers, and environmental conditions for the hypothetical sites were developed from data for each of the existing sites within the given region. Weighting criteria to account for the amount and types of SNF and HLW at each site were used in the development of the environmental data for the regional site, such that the results of the analyses for the hypothetical site were representative of the sum of the results of each actual site if they had been modeled independently. This report defines the actual site data used in development of this hypothetical site, shows how the individual site data was weighted to develop the regional site, and provides the weighted data used in the CSAR analysis. It is
Explosion of heterogeneous water droplet in a high-temperature gaseous region
NASA Astrophysics Data System (ADS)
Piskunov, M. V.; Shcherbinina, A. A.
2015-11-01
Using high-speed video recording tools (up to 105 frames per second) and «TEMA Automotive» and «Phantom Camera Control» software packages the experimental features of explosive disintegration, boiling and evaporation of water droplets with comparably sized solid inclusions heated in high-temperature (more than 650 K) gaseous region were determined. The necessary and sufficient conditions of explosive vapor formation achievement with the next heterogeneous water droplet disintegration were found.
ERIC Educational Resources Information Center
Pratt, Fran; And Others
A team-teaching program in ninth-grade world history at the Acton-Boxborough Regional High School in Acton, Massachusetts, is described. Developed by the teachers who share the course, the program emphasizes flexibility in classroom arrangement and learning group size in order to serve the needs of individual students. The goals of the team…
Analysis of the quasi-saturation region of high voltage VDMOS devices
NASA Astrophysics Data System (ADS)
Rebollo, J.; Figueras, E.; Millán, J.; Lora-Tamayo, E.; Serra-Mestres, F.
1987-02-01
The effect of the epitaxial layer on the quasi-saturation region of the ID( VD) characteristic of a high voltage n-channel VDMOS structure is analysed. The proposed model takes into account the cylindrical shape of the P-well/N --epilayer junction and the pinching effect of the current between neighbouring cells.
High School Attrition Rates across Texas Education Service Center Regions: 2009-10. IDRA Report
ERIC Educational Resources Information Center
Johnson, Roy L.
2011-01-01
Attrition rates are an indicator of a school's holding power, or ability to keep students enrolled in school and learning until they graduate. This study examines regional trends in Texas for the number and percent of students lost from public high school enrollment prior to graduation. A comparative analysis of 1985-86, 2005-06, 2006-07,…
ERIC Educational Resources Information Center
Moyer, Mary; Williams, Melissa
2011-01-01
The importance of reading is evident in every aspect of schooling and affects all areas of a student's daily life. At Delsea Regional High School in Franklinville, New Jersey, teachers (along with the school librarian) work to alter students' feelings about reading by using a variety of reading programs including the computerized reading…
The magnetic field structure in high-mass star formation regions
NASA Technical Reports Server (NTRS)
Davidson, Jacqueline A.; Schleuning, D.; Dotson, J. L.; Dowell, C. Darren; Hildebrand, Roger H.
1995-01-01
We present a preliminary analysis of far-IR polarimetric observations, which were made to study the magnetic field structure in the high-mass star formation regions of M42, NGC2024, and W3. These observations were made from the Kuiper Airborne Observatory (KAO), using the University of Chicago far-IR polarimeter, Stokes.
A Study of Risk Factors among High School Students in the Pacific Region.
ERIC Educational Resources Information Center
Kawakami, Alice J.; And Others
A study was conducted to provide a profile of variables related to the status of students at risk of failure in public high schools in the American-affiliated Pacific region. This report, which is supplemented by four political entity-level studies published separately, gives an overview of the entire study. Throughout the four entities (American…
ERIC Educational Resources Information Center
Heine, Hilda C.; Emesiochl, Masa Akii
2007-01-01
The provisions of the No Child Left Behind Act (NCLB) of 2001 for teacher quality direct that all students in U.S. public schools be taught by highly qualified teachers. Although the Pacific Region entities are trying to meet this teacher-quality mandate, most are still far from fulfilling the minimum education requirements for their teachers. By…