The Global Precipitation Measurement (GPM) Microwave Imager (GMI): Instrument Overview and Early On-Orbit Performance

NASA Technical Reports Server (NTRS)

Draper, David W.; Newell, David A.; Wentz, Frank J.; Krimchansky, Sergey; Jackson, Gail

2015-01-01

The Global Precipitation Measurement (GPM) mission is an international satellite mission that uses measurements from an advanced radar/radiometer system on a core observatory as reference standards to unify and advance precipitation estimates made by a constellation of research and operational microwave sensors. The GPM core observatory was launched on February 27, 2014 at 18:37 UT in a 65? inclination nonsun-synchronous orbit. GPM focuses on precipitation as a key component of the Earth's water and energy cycle, and has the capability to provide near-real-time observations for tracking severe weather events, monitoring freshwater resources, and other societal applications. The GPM microwave imager (GMI) on the core observatory provides the direct link to the constellation radiometer sensors, which fly mainly in polar orbits. The GMI sensitivity, accuracy, and stability play a crucial role in unifying the measurements from the GPM constellation of satellites. The instrument has exhibited highly stable operations through the duration of the calibration/validation period. This paper provides an overview of the GMI instrument and a report of early on-orbit commissioning activities. It discusses the on-orbit radiometric sensitivity, absolute calibration accuracy, and stability for each radiometric channel. Index Terms-Calibration accuracy, passive microwave remote sensing, radiometric sensitivity.

Phase 1 Study of the E-Selectin Inhibitor GMI 1070 in Patients with Sickle Cell Anemia

PubMed Central

Wun, Ted; Styles, Lori; DeCastro, Laura; Telen, Marilyn J.; Kuypers, Frans; Cheung, Anthony; Kramer, William; Flanner, Henry; Rhee, Seungshin; Magnani, John L.; Thackray, Helen

2014-01-01

Background Sickle cell anemia is an inherited disorder of hemoglobin that leads to a variety of acute and chronic complications. Abnormal cellular adhesion, mediated in part by selectins, has been implicated in the pathophysiology of the vaso-occlusion seen in sickle cell anemia, and selectin inhibition was able to restore blood flow in a mouse model of sickle cell disease. Methods We performed a Phase 1 study of the selectin inhibitor GMI 1070 in patients with sickle cell anemia. Fifteen patients who were clinically stable received GMI 1070 in two infusions. Results The drug was well tolerated without significant adverse events. There was a modest increase in total peripheral white blood cell count without clinical symptoms. Plasma concentrations were well-described by a two-compartment model with an elimination T1/2 of 7.7 hours and CLr of 19.6 mL/hour/kg. Computer-assisted intravital microscopy showed transient increases in red blood cell velocity in 3 of the 4 patients studied. Conclusions GMI 1070 was safe in stable patients with sickle cell anemia, and there was suggestion of increased blood flow in a subset of patients. At some time points between 4 and 48 hours after treatment with GMI 1070, there were significant decreases in biomarkers of endothelial activation (sE-selectin, sP-selectin, sICAM), leukocyte activation (MAC-1, LFA-1, PM aggregates) and the coagulation cascade (tissue factor, thrombin-antithrombin complexes). Development of GMI 1070 for the treatment of acute vaso-occlusive crisis is ongoing. Trial Registration ClinicalTrials.gov NCT00911495 PMID:24988449

A New 1DVAR Retrieval for AMSR2 and GMI: Validation and Sensitivites

NASA Astrophysics Data System (ADS)

Duncan, D.; Kummerow, C. D.

2015-12-01

A new non-raining retrieval has been developed for microwave imagers and applied to the GMI and AMSR2 sensors. With the Community Radiative Transfer Model (CRTM) as the forward model for the physical retrieval, a 1-dimensional variational method finds the atmospheric state which minimizes the difference between observed and simulated brightness temperatures. A key innovation of the algorithm development is a method to calculate the sensor error covariance matrix that is specific to the forward model employed and includes off-diagonal elements, allowing the algorithm to handle various forward models and sensors with little cross-talk. The water vapor profile is resolved by way of empirical orthogonal functions (EOFs) and then summed to get total precipitable water (TPW). Validation of retrieved 10m wind speed, TPW, and sea surface temperature (SST) is performed via comparison with buoys and radiosondes as well as global models and other remotely sensed products. In addition to the validation, sensitivity experiments investigate the impact of ancillary data on the under-constrained retrieval, a concern for climate data records that strive to be independent of model biases. The introduction of model analysis data is found to aid the algorithm most at high frequency channels and affect TPW retrievals, whereas wind and cloud water retrievals show little effect from ingesting further ancillary data.

Chemistry Simulations using the MERRA-2 Reanalysis with the GMI CTM and Replay in Support of the Atmospheric Composition Community

NASA Technical Reports Server (NTRS)

Oman, Luke D.; Strahan, Susan E.

2017-01-01

Simulations using reanalysis meteorological fields have long been used to understand the causes of atmospheric composition change in the recent past. Using the new MERRA-2 reanalysis, we are conducting chemistry simulations to create products covering 1980-2016 for the atmospheric composition community. These simulations use the Global Modeling Initiative (GMI) chemical mechanism in two different models: the GMI Chemical Transport Model (CTM) and the GEOS-5 model in Replay mode. Replay mode means an integration of the GEOS-5 general circulation model that is incrementally adjusted each time step toward the MERRA-2 reanalysis. The GMI CTM is a 1 deg x 1.25 deg simulation and the MERRA-2 GMI Replay simulation uses the native MERRA-2 grid of approximately 1/2 deg horizontal resolution on the cubed sphere. A specialized set of transport diagnostics is included in both runs to better understand trace gas transport and its variability in the recent past.

Extremely high frequency RF effects on electronics.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Loubriel, Guillermo Manuel; Vigliano, David; Coleman, Phillip Dale

The objective of this work was to understand the fundamental physics of extremely high frequency RF effects on electronics. To accomplish this objective, we produced models, conducted simulations, and performed measurements to identify the mechanisms of effects as frequency increases into the millimeter-wave regime. Our purpose was to answer the questions, 'What are the tradeoffs between coupling, transmission losses, and device responses as frequency increases?', and, 'How high in frequency do effects on electronic systems continue to occur?' Using full wave electromagnetics codes and a transmission-line/circuit code, we investigated how extremely high-frequency RF propagates on wires and printed circuit boardmore » traces. We investigated both field-to-wire coupling and direct illumination of printed circuit boards to determine the significant mechanisms for inducing currents at device terminals. We measured coupling to wires and attenuation along wires for comparison to the simulations, looking at plane-wave coupling as it launches modes onto single and multiconductor structures. We simulated the response of discrete and integrated circuit semiconductor devices to those high-frequency currents and voltages, using SGFramework, the open-source General-purpose Semiconductor Simulator (gss), and Sandia's Charon semiconductor device physics codes. This report documents our findings.« less

Magnetic nanoparticle detection method employing non-linear magnetoimpedance effects

NASA Astrophysics Data System (ADS)

Beato-López, J. J.; Pérez-Landazábal, J. I.; Gómez-Polo, C.

2017-04-01

In this work, a sensitive tool to detect magnetic nanoparticles (Fe3O4) based on a non-linear Giant Magnetoimpedance (GMI) effect is presented. The GMI sensor is designed with four nearly zero magnetostrictive ribbons connected in series and was analysed as a function of a constant external magnetic field and exciting frequency. The influence of the magnetic nanoparticles deposited on the ribbon surface was characterized using the first (fundamental) and second (non-linear) harmonics of the magnetoinductive voltage. The results show a clear enhancement of the sensor response in the high magnetic field region (H = 1.5 kA/m) as a consequence of the stray field generated by the magnetic nanoparticles on the GMI ribbons' surface. The highest sensitivity ratios are obtained for the non-linear component in comparison with the fundamental response. The results open a new research strategy in magnetic nanoparticle detection.

Chemistry Simulations Using MERRA-2 Reanalysis with the GMI CTM and Replay in Support of the Atmospheric Composition Community

NASA Technical Reports Server (NTRS)

Oman, Luke D.; Strahan, Susan E.

2016-01-01

Simulations using reanalyzed meteorological conditions have been long used to understand causes of atmospheric composition change over the recent past. Using the new Modern-Era Retrospective analysis for Research and Applications, version 2 (MERRA-2) meteorology, chemistry simulations are being conducted to create products covering 1980-2016 for the atmospheric composition community. These simulations use the Global Modeling Initiative (GMI) chemical mechanism in two different models: the GMI Chemical Transport Model (CTM) and the GEOS-5 model developed Replay mode. Replay mode means an integration of the GEOS-5 general circulation model that is incrementally adjusted each time step toward the MERRA-2 analysis. The GMI CTM is a 1 x 1.25 simulation and the MERRA-2 GMI Replay simulation uses the native MERRA-2 approximately horizontal resolution on the cubed sphere. The Replay simulations is driven by the online use of key MERRA-2 meteorological variables (i.e. U, V, T, and surface pressure) with all other variables calculated in response to those variables. A specialized set of transport diagnostics is included in both runs to better understand trace gas transport and changes over the recent past.

GMI-1070, a novel pan-selectin antagonist, reverses acute vascular occlusions in sickle cell mice

PubMed Central

Chang, Jungshan; Patton, John T.; Sarkar, Arun; Ernst, Beat

2010-01-01

Leukocyte adhesion in the microvasculature influences blood rheology and plays a key role in vaso-occlusive manifestations of sickle cell disease. Notably, polymorphonuclear neutrophils (PMNs) can capture circulating sickle red blood cells (sRBCs) in inflamed venules, leading to critical reduction in blood flow and vaso-occlusion. Recent studies have suggested that E-selectin expression by endothelial cells plays a key role by sending activating signals that lead to the activation of Mac-1 at the leading edge of PMNs, thereby allowing RBC capture. Thus, the inhibition of E-selectin may represent a valuable target in this disease. Here, we have tested the biologic properties of a novel synthetic pan-selectin inhibitor, GMI-1070, with in vitro assays and in a humanized model of sickle cell vaso-occlusion analyzed by intravital microscopy. We have found that GMI-1070 predominantly inhibited E-selectin–mediated adhesion and dramatically inhibited sRBC-leukocyte interactions, leading to improved microcirculatory blood flow and improved survival. These results suggest that GMI-1070 may represent a valuable novel therapeutic intervention for acute sickle cell crises that should be further evaluated in a clinical trial. PMID:20508165

The Disturbing Effect of the Stray Magnetic Fields on Magnetoimpedance Sensors

PubMed Central

Wang, Tao; Zhou, Yong; Lei, Chong; Zhi, Shaotao; Guo, Lei; Li, Hengyu; Wu, Zhizheng; Xie, Shaorong; Luo, Jun; Pu, Huayan

2016-01-01

The disturbing effect of the stray magnetic fields of Fe-based amorphous ribbons on the giant magnetoimpedance (GMI) sensor has been investigated systematically in this paper. Two simple methods were used for examining the disturbing effect of the stray magnetic fields of ribbons on the GMI sensor. In order to study the influence of the stray magnetic fields on the GMI effect, the square-shaped amorphous ribbons were tested in front, at the back, on the left and on the top of a meander-line GMI sensor made up of soft ferromagnetic films, respectively. Experimental results show that the presence of ribbons in front or at the back of GMI sensor shifts the GMI curve to a lower external magnetic field. On the contrary, the presence of ribbons on the left or on the top of the GMI sensor shifts the GMI curve to a higher external magnetic field, which is related to the coupling effect of the external magnetic field and the stray magnetic fields. The influence of the area and angle of ribbons on GMI was also studied in this work. The GMI sensor exhibits high linearity for detection of the stray magnetic fields, which has made it feasible to construct a sensitive magnetometer for detecting the typical stray magnetic fields of general soft ferromagnetic materials. PMID:27763498

Design and Fabrication of a Miniaturized GMI Magnetic Sensor Based on Amorphous Wire by MEMS Technology

PubMed Central

Chen, Jiawen; Li, Jianhua; Li, Yiyuan; Chen, Yulong

2018-01-01

A miniaturized Co-based amorphous wire GMI (Giant magneto-impedance) magnetic sensor was designed and fabricated in this paper. The Co-based amorphous wire was used as the sense element due to its high sensitivity to the magnetic field. A three-dimensional micro coil surrounding the Co-based amorphous wire was fabricated by MEMS (Micro-Electro-Mechanical System) technology, which was used to extract the electrical signal. The three-dimensional micro pick-up coil was designed and simulated with HFSS (High Frequency Structure Simulator) software to determine the key parameters. Surface micro machining MEMS (Micro-Electro-Mechanical System) technology was employed to fabricate the three-dimensional coil. The size of the developed amorphous wire magnetic sensor is 5.6 × 1.5 × 1.1 mm3. Helmholtz coil was used to characterize the performance of the device. The test results of the sensor sample show that the voltage change is 130 mV/Oe and the linearity error is 4.83% in the range of 0~45,000 nT. The results indicate that the developed miniaturized magnetic sensor has high sensitivity. By testing the electrical resistance of the samples, the results also showed high uniformity of each device. PMID:29494477

Evaluation of GMI and PMI diffeomorphic-based demons algorithms for aligning PET and CT Images.

PubMed

Yang, Juan; Wang, Hongjun; Zhang, You; Yin, Yong

2015-07-08

Fusion of anatomic information in computed tomography (CT) and functional information in 18F-FDG positron emission tomography (PET) is crucial for accurate differentiation of tumor from benign masses, designing radiotherapy treatment plan and staging of cancer. Although current PET and CT images can be acquired from combined 18F-FDG PET/CT scanner, the two acquisitions are scanned separately and take a long time, which may induce potential positional errors in global and local caused by respiratory motion or organ peristalsis. So registration (alignment) of whole-body PET and CT images is a prerequisite for their meaningful fusion. The purpose of this study was to assess the performance of two multimodal registration algorithms for aligning PET and CT images. The proposed gradient of mutual information (GMI)-based demons algorithm, which incorporated the GMI between two images as an external force to facilitate the alignment, was compared with the point-wise mutual information (PMI) diffeomorphic-based demons algorithm whose external force was modified by replacing the image intensity difference in diffeomorphic demons algorithm with the PMI to make it appropriate for multimodal image registration. Eight patients with esophageal cancer(s) were enrolled in this IRB-approved study. Whole-body PET and CT images were acquired from a combined 18F-FDG PET/CT scanner for each patient. The modified Hausdorff distance (d(MH)) was used to evaluate the registration accuracy of the two algorithms. Of all patients, the mean values and standard deviations (SDs) of d(MH) were 6.65 (± 1.90) voxels and 6.01 (± 1.90) after the GMI-based demons and the PMI diffeomorphic-based demons registration algorithms respectively. Preliminary results on oncological patients showed that the respiratory motion and organ peristalsis in PET/CT esophageal images could not be neglected, although a combined 18F-FDG PET/CT scanner was used for image acquisition. The PMI diffeomorphic-based demons

Gender Identification Using High-Frequency Speech Energy: Effects of Increasing the Low-Frequency Limit.

PubMed

Donai, Jeremy J; Halbritter, Rachel M

The purpose of this study was to investigate the ability of normal-hearing listeners to use high-frequency energy for gender identification from naturally produced speech signals. Two experiments were conducted using a repeated-measures design. Experiment 1 investigated the effects of increasing high-pass filter cutoff (i.e., increasing the low-frequency spectral limit) on gender identification from naturally produced vowel segments. Experiment 2 studied the effects of increasing high-pass filter cutoff on gender identification from naturally produced sentences. Confidence ratings for the gender identification task were also obtained for both experiments. Listeners in experiment 1 were capable of extracting talker gender information at levels significantly above chance from vowel segments high-pass filtered up to 8.5 kHz. Listeners in experiment 2 also performed above chance on the gender identification task from sentences high-pass filtered up to 12 kHz. Cumulatively, the results of both experiments provide evidence that normal-hearing listeners can utilize information from the very high-frequency region (above 4 to 5 kHz) of the speech signal for talker gender identification. These findings are at variance with current assumptions regarding the perceptual information regarding talker gender within this frequency region. The current results also corroborate and extend previous studies of the use of high-frequency speech energy for perceptual tasks. These findings have potential implications for the study of information contained within the high-frequency region of the speech spectrum and the role this region may play in navigating the auditory scene, particularly when the low-frequency portion of the spectrum is masked by environmental noise sources or for listeners with substantial hearing loss in the low-frequency region and better hearing sensitivity in the high-frequency region (i.e., reverse slope hearing loss).

Assimilation of all-weather GMI and ATMS observations into HWRF

NASA Astrophysics Data System (ADS)

Moradi, I.; Evans, F.; McCarty, W.; Marks, F.; Eriksson, P.

2017-12-01

We propose a novel Bayesian Monte Carlo Integration (BMCI) technique to retrieve the profiles of temperature, water vapor, and cloud liquid/ice water content from microwave cloudy measurements in the presence of TCs. These retrievals then can either be directly used by meteorologists to analyze the structure of TCs or be assimilated to provide accurate initial conditions for the NWP models. The technique is applied to the data from the Advanced Technology Microwave Sounder (ATMS) onboard Suomi National Polar-orbiting Partnership (NPP) and Global Precipitation Measurement (GPM) Microwave Imager (GMI).

Giant magnetic impedance of wires with a thin magnetic coating

NASA Astrophysics Data System (ADS)

Kurlyandskaya, G. V.; Bebenin, N. G.; Vas'kovsky, V. O.

2011-02-01

In this review, we analyzed and generalized the results of experimental investigations of physical processes that occur in composite wires with a thin magnetic coating under the conditions of the appearance in them of a giant magnetoimpedance (GMI) effect. Principles of the measurements of high-frequency impedance are described in short; basic definitions are given, and the differences in the linear and nonlinear GMI regimes are described. Data are systemized on the giant magnetic impedance of wires with a thin magnetic coating (composite materials) under the conditions of a strong nonlinearity of the GMI effect, which is accompanied by the appearance of higher harmonics in the output signal. The extremely high susceptibility of the harmonic parameters to external actions can be used in the technical applications for creating ultrasensitive detectors of low magnetic fields. Special attention is paid to model calculations, which confirm the fact that the experimentally observed features of a nonlinear GMI effect are connected with the high sensitivity of the magnetic system to a circular magnetic field near the spin-reorientation phase transitions. Fine features of the effective magnetic anisotropy can play the key role and therefore cannot be ignored in the general case.

Frequencies of inaudible high-frequency sounds differentially affect brain activity: positive and negative hypersonic effects.

PubMed

Fukushima, Ariko; Yagi, Reiko; Kawai, Norie; Honda, Manabu; Nishina, Emi; Oohashi, Tsutomu

2014-01-01

The hypersonic effect is a phenomenon in which sounds containing significant quantities of non-stationary high-frequency components (HFCs) above the human audible range (max. 20 kHz) activate the midbrain and diencephalon and evoke various physiological, psychological and behavioral responses. Yet important issues remain unverified, especially the relationship existing between the frequency of HFCs and the emergence of the hypersonic effect. In this study, to investigate the relationship between the hypersonic effect and HFC frequencies, we divided an HFC (above 16 kHz) of recorded gamelan music into 12 band components and applied them to subjects along with an audible component (below 16 kHz) to observe changes in the alpha2 frequency component (10-13 Hz) of spontaneous EEGs measured from centro-parieto-occipital regions (Alpha-2 EEG), which we previously reported as an index of the hypersonic effect. Our results showed reciprocal directional changes in Alpha-2 EEGs depending on the frequency of the HFCs presented with audible low-frequency component (LFC). When an HFC above approximately 32 kHz was applied, Alpha-2 EEG increased significantly compared to when only audible sound was applied (positive hypersonic effect), while, when an HFC below approximately 32 kHz was applied, the Alpha-2 EEG decreased (negative hypersonic effect). These findings suggest that the emergence of the hypersonic effect depends on the frequencies of inaudible HFC.

Diurnal Variation of Tropical Ice Cloud Microphysics inferred from Global Precipitation Measurement Microwave Imager (GPM-GMI)'s Polarimetric Measurement

NASA Astrophysics Data System (ADS)

Gong, J.; Zeng, X.; Wu, D. L.; Li, X.

2017-12-01

Diurnal variation of tropical ice cloud has been well observed and examined in terms of the area of coverage, occurring frequency, and total mass, but rarely on ice microphysical parameters (habit, size, orientation, etc.) because of lack of direct measurements of ice microphysics on a high temporal and spatial resolutions. This accounts for a great portion of the uncertainty in evaluating ice cloud's role on global radiation and hydrological budgets. The design of Global Precipitation Measurement (GPM) mission's procession orbit gives us an unprecedented opportunity to study the diurnal variation of ice microphysics on the global scale for the first time. Dominated by cloud ice scattering, high-frequency microwave polarimetric difference (PD, namely the brightness temperature difference between vertically- and horizontally-polarized paired channel measurements) from the GPM Microwave Imager (GMI) has been proven by our previous study to be very valuable to infer cloud ice microphysical properties. Using one year of PD measurements at 166 GHz, we found that cloud PD exhibits a strong diurnal cycle in the tropics (25S-25N). The peak PD amplitude varies as much as 35% over land, compared to only 6% over ocean. The diurnal cycle of the peak PD value is strongly anti-correlated with local ice cloud occurring frequency and the total ice mass with a leading period of 3 hours for the maximum correlation. The observed PD diurnal cycle can be explained by the change of ice crystal axial ratio. Using a radiative transfer model, we can simulate the observed 166 GHz PD-brightness temperature curve as well as its diurnal variation using different axial ratio values, which can be caused by the diurnal variation of ice microphysical properties including particle size, percentage of horizontally-aligned non-spherical particles, and ice habit. The leading of the change of PD ahead of ice cloud mass and occurring frequency implies the important role microphysics play in the

Permalloy-Based Thin Film Structures: Magnetic Properties and the Giant Magnetoimpedance Effect in the Temperature Range Important for Biomedical Applications

PubMed Central

Chlenova, Anna A.; Moiseev, Alexey A.; Derevyanko, Mikhail S.; Semirov, Aleksandr V.; Lepalovsky, Vladimir N.

2017-01-01

Permalloy-based thin film structures are excellent materials for sensor applications. Temperature dependencies of the magnetic properties and giant magneto-impedance (GMI) were studied for Fe19Ni81-based multilayered structures obtained by the ion-plasma sputtering technique. Selected temperature interval of 25 °C to 50 °C corresponds to the temperature range of functionality of many devices, including magnetic biosensors. A (Cu/FeNi)5/Cu/(Cu/FeNi)5 multilayered structure with well-defined traverse magnetic anisotropy showed an increase in the GMI ratio for the total impedance and its real part with temperature increased. The maximum of the GMI of the total impedance ratio ΔZ/Z = 56% was observed at a frequency of 80 MHz, with a sensitivity of 18%/Oe, and the maximum GMI of the real part ΔR/R = 170% at a frequency of 10 MHz, with a sensitivity of 46%/Oe. As the magnetization and direct current electrical resistance vary very little with the temperature, the most probable mechanism of the unexpected increase of the GMI sensitivity is the stress relaxation mechanism associated with magnetoelastic anisotropy. PMID:28817084

Anti-inflammatory effects of low-intensity extremely high-frequency electromagnetic radiation: frequency and power dependence.

PubMed

Gapeyev, A B; Mikhailik, E N; Chemeris, N K

2008-04-01

Using a model of acute zymosan-induced footpad edema in NMRI mice, the frequency and power dependence of anti-inflammatory effect of low-intensity extremely high-frequency electromagnetic radiation (EHF EMR) was found. Single whole-body exposure of animals to EHF EMR at the intensity of 0.1 mW/cm(2) for 20 min at 1 h after zymosan injection reduced both the footpad edema and local hyperthermia on average by 20% at the frequencies of 42.2, 51.8, and 65 GHz. Some other frequencies from the frequency range of 37.5-70 GHz were less effective or not effective at all. At fixed frequency of 42.2 GHz and intensity of 0.1 mW/cm(2), the effect had bell-shaped dependence on exposure duration with a maximum at 20-40 min. Reduction of intensity to 0.01 mW/cm(2) resulted in a change of the effect dependence on exposure duration to a linear one. Combined action of cyclooxygenase inhibitor sodium diclofenac and EHF EMR exposure caused a partial additive effect of decrease in footpad edema. Combined action of antihistamine clemastine and EHF EMR exposure caused a dose-dependent abolishment of the anti-inflammatory effect of EHF EMR. The results obtained suggest that arachidonic acid metabolites and histamine are involved in realization of anti-inflammatory effects of low-intensity EHF EMR. (c) 2007 Wiley-Liss, Inc.

Design, Development and Testing of the GMI Launch Locks

NASA Technical Reports Server (NTRS)

Sexton, Adam; Dayton, Chris; Wendland, Ron; Pellicciotti, Joseph

2011-01-01

Ball Aerospace will deliver the GPM Microwave Imager (GMI), to NASA as one of the 3 instruments to fly on the Global Precipitation Measurement (GPM) mission, for launch in 2013. The radiometer, when deployed, is over 8 feet tall and rotates at 32 revolutions per minute (RPM) can be described as a collection of mechanisms working to achieve its scientific objectives. This collection precisely positions a 1.2 meter reflector to a 48.5 degree off nadir angle while rotating, transferring electrical power and signals to and from the RF receivers, designs two very stable calibration sources, and provides the structural integrity of all the components. There are a total of 7 launch restraints coupling across the moving and stationary elements of the structure,. Getting from design to integration will be the focus of this paper.

Combined current-modulation annealing induced enhancement of giant magnetoimpedance effect of Co-rich amorphous microwires

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Jingshun, E-mail: jingshun-liu@163.com, E-mail: faxiang.qin@gmail.com; School of Materials Science and Engineering, Inner Mongolia University of Technology, Hohhot 010051; Qin, Faxiang, E-mail: jingshun-liu@163.com, E-mail: faxiang.qin@gmail.com

2014-05-07

We report on a combined current-modulation annealing (CCMA) method, which integrates the optimized pulsed current (PC) and DC annealing techniques, for improving the giant magnetoimpedance (GMI) effect and its field sensitivity of Co-rich amorphous microwires. Relative to an as-prepared Co{sub 68.2}Fe{sub 4.3}B{sub 15}Si{sub 12.5} wire, CCMA is shown to remarkably improve the GMI response of the wire. At 10 MHz, the maximum GMI ratio and its field sensitivity of the as-prepared wire were, respectively, increased by 3.5 and 2.28 times when subjected to CCMA. CCMA increased atomic order orientation and circumferential permeability of the wire by the co-action of high-density pulsedmore » magnetic field energy and thermal activation energy at a PC annealing stage, as well as the formation of uniform circular magnetic domains by a stable DC magnetic field at a DC annealing stage. The magnetic moment can overcome eddy-current damping or nail-sticked action in rotational magnetization, giving rise to a double-peak feature and wider working field range (up to ±2 Oe) at relatively higher frequency (f ≥ 1 MHz)« less

Enhanced giant magnetoimpedance in heterogeneous nanobrush

PubMed Central

2012-01-01

A highly sensitive and large working range giant magnetoimpedance (GMI) effect is found in the novel nanostructure: nanobrush. The nanostructure is composed of a soft magnetic nanofilm and a nanowire array, respectively fabricated by RF magnetron sputtering and electrochemical deposition. The optimal GMI ratio of nanobrush is promoted to more than 250%, higher than the pure FeNi film and some sandwich structures at low frequency. The design of this structure is based on the vortex distribution of magnetic moments in thin film, and it can be induced by the exchange coupling effect between the interfaces of nanobrush. PMID:22963551

The QBO Impact on Stratospheric Composition as Revealed by the MERRA-2 GMI Simulation and NASA Satellite Observations

NASA Astrophysics Data System (ADS)

Oman, L.; Strahan, S. E.

2017-12-01

The Quasi-Biennial Oscillation (QBO) is the dominant mode of variability in the tropical stratosphere on interannual time scales. It has been shown to impact both stratospheric dynamics and important trace gas constituent distributions. The QBO timing with respect to the seasonal cycle in each hemisphere is significant in determining its impact on up to decadal scale variability. The composition response to the QBO is examined using the new MERRA-2 GMI "Replay" simulation, an atmospheric composition community resource, run at the native MERRA-2 approximately ½° horizontal resolution on the cubed sphere. MERRA-2 GMI is driven by the online use of key MERRA-2 meteorological quantities (i.e. U, V, T, and P) with all other variables calculated in response to those and boundary condition forcings from 1980-2016. The simulation combined with NASA's UARS and Aura satellite measurements have allowed us to quantify the impact of the QBO on stratospheric composition in more detail than was ever possible before. Revealing preferential pathways and transport timings necessary in understanding the QBO impact on composition throughout the stratosphere.

Modelling switching-time effects in high-frequency power conditioning networks

NASA Technical Reports Server (NTRS)

Owen, H. A.; Sloane, T. H.; Rimer, B. H.; Wilson, T. G.

1979-01-01

Power transistor networks which switch large currents in highly inductive environments are beginning to find application in the hundred kilohertz switching frequency range. Recent developments in the fabrication of metal-oxide-semiconductor field-effect transistors in the power device category have enhanced the movement toward higher switching frequencies. Models for switching devices and of the circuits in which they are imbedded are required to properly characterize the mechanisms responsible for turning on and turning off effects. Easily interpreted results in the form of oscilloscope-like plots assist in understanding the effects of parametric studies using topology oriented computer-aided analysis methods.

Magnetic sensor technology based on giant magneto-impedance effect in amorphous wires

NASA Astrophysics Data System (ADS)

Wang, X.; Teng, Y.; Wang, C.; Li, Q.

2012-12-01

This project focuses on giant magneto-impedance (GMI) effect that found in the soft magnetic amorphous wires in recent years, when AC current through the amorphous wire, induced voltage in the wires would change sensitively with a small external magnetic field along the wire vertical imposed changes. GMI magnetic sensor could compensate for the shortcomings of the traditional magnetic sensors and detect weak magnetic field, meanwhile the characteristics of high stability, high sensitivity, high resolution, fast response and low power consumption, which makes it becoming the focus of extensive research at home and abroad and being new mode of the next age of the physical geography observation. The emphasis of the project is the research on the high sensitivity amorphous wire detector and the low noise capability circuit design. In this paper, it is analyzed the theory of the Amorphous Wire Giant-Magneto-Impedance (AWGMI) effect and its influence factors in details, and expatiated the sensor principle based on AWGMI. On the basis of AWGMI, the experimental system of the micro-magnetic sensor is designed, which is composed of the detecting signals, processing and collecting data, display and transmitting data circuit and corresponding functional software etc. The properties of this kind of micro-magnetic sensor are studied by experiments, such as its linearity, sensitivity, frequency response, noise, stability and temperature properties and so on, especially analyzed the relation of the drive signals with all kinds of characteristics. The results show that there is no direct relationship between the frequency of the drive signals and linear property of the sensor. But with the increase of its frequency, some fluctuation appears on the characteristic curves; the direct relation is found between the frequency of the drive signal and sensitivity, with the increase of the frequency, AWGMI effect increases monotonously. It leads to the amplitude of the output voltage

Features of anti-inflammatory effects of modulated extremely high-frequency electromagnetic radiation.

PubMed

Gapeyev, Andrew B; Mikhailik, Elena N; Chemeris, Nikolay K

2009-09-01

Using a model of acute zymosan-induced paw edema in NMRI mice, we test the hypothesis that anti-inflammatory effects of extremely high-frequency electromagnetic radiation (EHF EMR) can be essentially modified by application of pulse modulation with certain frequencies. It has been revealed that a single exposure of animals to continuous EHF EMR for 20 min reduced the exudative edema of inflamed paw on average by 19% at intensities of 0.1-0.7 mW/cm(2) and frequencies from the range of 42.2-42.6 GHz. At fixed effective carrier frequency of 42.2 GHz, the anti-inflammatory effect of EHF EMR did not depend on modulation frequencies, that is, application of different modulation frequencies from the range of 0.03-100 Hz did not lead to considerable changes in the effect level. On the contrary, at "ineffective" carrier frequencies of 43.0 and 61.22 GHz, the use of modulation frequencies of 0.07-0.1 and 20-30 Hz has allowed us to restore the effect up to a maximal level. The results obtained show the critical dependence of anti-inflammatory action of low-intensity EHF EMR on carrier and modulation frequencies. Within the framework of this study, the possibility of changing the level of expected biological effect of modulated EMR by a special selection of combination of carrier and modulation frequencies is confirmed.

Asymmetric giant magnetoimpedance effect created by micro magnets

NASA Astrophysics Data System (ADS)

Atalay, S.; Izgi, T.; Buznikov, N. A.; Kolat, V. S.

2018-05-01

Asymmetric giant magnetoimpedance (AGMI) effect has been investigated in as-prepared and current annealed amorphous (Co0.9Fe0.05Ni0.05)75Si15B10 ribbons. Asymmetry was created by micro magnets. Different numbers of magnets were used and it was found that increasing number of magnet, the shift in AGMI curves increases. When two micro magnets were placed 1 cm away from the ends of ribbon, a distortion in two peak shape of the GMI curve was observed. At high frequency range, a linear change in the AGMI was observed for the current annealed sample.

[Membranotropic effects of electromagnetic radiation of extremely high frequency on Escherichia coli].

PubMed

Trchunian, A; Ogandzhanian, E; Sarkisian, E; Gonian, S; Oganesian, A; Oganesian, S

2001-01-01

It was found that "sound" electromagnetic radiations of extremely high frequencies (53.5-68 GHz) or millimeter waves (wavelength range of 4.2-5.6 mm) of low intensity (power density 0.01 mW) have a bactericidal effect on Escherichia coli bacteria. It was shown that exposure to irradiation of extremely high frequencies increases the electrokinetic potential and surface change density of bacteria and decreases of membrane potential. The total secretion of hydrogen ions was suppressed, the H+ flux from the cytoplasm to medium decreased, and the flux of N,N'-dicyclohexylcarbodiimide-sensitive potassium ions increased, which was accompanied by changes in the stoichiometry of these fluxes and an increase in the sensitivity of H+ ions to N,N'-dicyclohexylcarbodiimide. The effects depended on duration of exposure: as the time of exposure increased, the bactericidal effect increased, whereas the membranotropic effects decreased. The effects also depended on growth phase of bacteria: the irradiation affected the cells in the stationary but not in the logarithmic phase. It is assumed that the H(+)-ATPase complex F0F1 is involved in membranotropic effects of electromagnetic radiation of extremely high frequencies. Presumably, there are some compensatory mechanisms that eliminate the membranotropic effects.

The Ozone Budget in the Upper Troposphere from Global Modeling Initiative (GMI)Simulations

NASA Technical Reports Server (NTRS)

Rodriquez, J.; Duncan, Bryan N.; Logan, Jennifer A.

2006-01-01

Ozone concentrations in the upper troposphere are influenced by in-situ production, long-range tropospheric transport, and influx of stratospheric ozone, as well as by photochemical removal. Since ozone is an important greenhouse gas in this region, it is particularly important to understand how it will respond to changes in anthropogenic emissions and changes in stratospheric ozone fluxes.. This response will be determined by the relative balance of the different production, loss and transport processes. Ozone concentrations calculated by models will differ depending on the adopted meteorological fields, their chemical scheme, anthropogenic emissions, and treatment of the stratospheric influx. We performed simulations using the chemical-transport model from the Global Modeling Initiative (GMI) with meteorological fields from (It)h e NASA Goddard Institute for Space Studies (GISS) general circulation model (GCM), (2) the atmospheric GCM from NASA's Global Modeling and Assimilation Office(GMAO), and (3) assimilated winds from GMAO . These simulations adopt the same chemical mechanism and emissions, and adopt the Synthetic Ozone (SYNOZ) approach for treating the influx of stratospheric ozone -. In addition, we also performed simulations for a coupled troposphere-stratosphere model with a subset of the same winds. Simulations were done for both 4degx5deg and 2degx2.5deg resolution. Model results are being tested through comparison with a suite of atmospheric observations. In this presentation, we diagnose the ozone budget in the upper troposphere utilizing the suite of GMI simulations, to address the sensitivity of this budget to: a) the different meteorological fields used; b) the adoption of the SYNOZ boundary condition versus inclusion of a full stratosphere; c) model horizontal resolution. Model results are compared to observations to determine biases in particular simulations; by examining these comparisons in conjunction with the derived budgets, we may pinpoint

High Frequency Radar Astronomy With HAARP

DTIC Science & Technology

2003-01-01

High Frequency Radar Astronomy With HAARP Paul Rodriguez Naval Research Laboratory Information Technology Division Washington, DC 20375, USA Edward...a period of several years, the High frequency Active Auroral Research Program ( HAARP ) transmitting array near Gakona, Alaska, has increased in total...high frequency (HF) radar facility used for research purposes. The basic science objective of HAARP is to study nonlinear effects associated with

High-frequency effects in antiferromagnetic Sr3Ir2O7

NASA Astrophysics Data System (ADS)

Williamson, Morgan; Seinige, Heidi; Shen, Shida; Wang, Cheng; Cao, Gang; Zhou, Jianshi; Goodenough, John; Tsoi, Maxim

Antiferromagnetic (AFM) spintronics is one of many promising routes for `beyond the CMOS' technologies where unique properties of AFM materials are exploited to achieve new and improved functionalities. AFMs are especially interesting for high-speed memory applications thanks to their high natural frequencies. Here we report the effects of high-frequency (microwave) currents on transport properties of antiferromagnetic Mott insulator Sr3Ir2O7. The microwaves at 3-7 GHz were found to affect the material's current-voltage characteristic and produce resonance-like features that we tentatively associate with the dissipationless magnonics recently predicted to occur in antiferromagnetic insulators subject to ac electric fields. Our observations support the potential of antiferromagnetic materials for high-speed/high-frequency spintronic applications. This work was supported in part by C-SPIN, one of six centers of STARnet, a Semiconductor Research Corporation program, sponsored by MARCO and DARPA, by NSF Grants DMR-1207577, DMR-1265162, DMR-1600057, and DMR-1122603, and by the King Abdullah University of Science and Technology (KAUST) Office of Sponsored Research (OSR) under Award No. OSR-2015-CRG4-2626.

Pulsed-High Field/High-Frequency EPR Spectroscopy

NASA Astrophysics Data System (ADS)

Fuhs, Michael; Moebius, Klaus

Pulsed high-field/high-frequency electron paramagnetic resonance (EPR) spectroscopy is used to disentangle many kinds of different effects often obscured in continuous wave (cw) EPR spectra at lower magnetic fields/microwave frequencies. While the high magnetic field increases the resolution of G tensors and of nuclear Larmor frequencies, the high frequencies allow for higher time resolution for molecular dynamics as well as for transient paramagnetic intermediates studied with time-resolved EPR. Pulsed EPR methods are used for example for relaxation-time studies, and pulsed Electron Nuclear DOuble Resonance (ENDOR) is used to resolve unresolved hyperfine structure hidden in inhomogeneous linewidths. In the present article we introduce the basic concepts and selected applications to structure and mobility studies on electron transfer systems, reaction centers of photosynthesis as well as biomimetic models. The article concludes with an introduction to stochastic EPR which makes use of an other concept for investigating resonance systems in order to increase the excitation bandwidth of pulsed EPR. The limited excitation bandwidth of pulses at high frequency is one of the main limitations which, so far, made Fourier transform methods hardly feasible.

The effect of changing disk parameters on whirling frequency of high speed rotor system

NASA Astrophysics Data System (ADS)

Wahab, A. M. Abdul; Rasid, Z. A.; Abu, A.; Rudin, N. F. Mohd Noor; Yakub, F.

2017-12-01

The requirement for efficiency improvement of machines has caused machine rotor to be designed to rotate at high speeds. It is known that whirling natural frequency of a shaft changes with the change of shaft speed and the design needs to avoid points of resonance where the whirling frequency equals the shaft speed. At high speeds, a shaft may have to carry a huge torque along and this torsional effect has been neglected in past shaft analyses. Whirling behaviour of high speed rotating shaft is investigated in this study with consideration of the torsional effect of the shaft. The shaft system under study consists of a shaft, discs and two bearings, and the focus is on the effect of the disc parameters. A finite element formulation is developed based on Nelson’s 5 degrees of freedom (DOF) per node element that includes the torsional degree of freedom. Bolotin’s method is applied to the derived Mathieu-Hill type of equation to get quadratic eigenvalues problem that gives the forward and backward frequencies of the shaft. Campbell’s diagrams are drawn in studying the effect of discs on the whirling behaviour of the shaft. It is found that the addition of disks on the shaft decreases the whirling frequency of the shaft and the frequency is lower for mass located at the centre of the shaft compared to the one located near to the end. The effect of torsional motion is found to be significant where the difference between critical speed of 4DOF and 5DOF models can be as high as 15%.

Frequency-Swept Integrated Solid Effect.

PubMed

Can, Thach V; Weber, Ralph T; Walish, Joseph J; Swager, Timothy M; Griffin, Robert G

2017-06-06

The efficiency of continuous wave dynamic nuclear polarization (DNP) experiments decreases at the high magnetic fields used in contemporary high-resolution NMR applications. To recover the expected signal enhancements from DNP, we explored time domain experiments such as NOVEL which matches the electron Rabi frequency to the nuclear Larmor frequency to mediate polarization transfer. However, satisfying this matching condition at high frequencies is technically demanding. As an alternative we report here frequency-swept integrated solid effect (FS-ISE) experiments that allow low power sweeps of the exciting microwave frequencies to constructively integrate the negative and positive polarizations of the solid effect, thereby producing a polarization efficiency comparable to (±10 % difference) NOVEL. Finally, the microwave frequency modulation results in field profiles that exhibit new features that we coin the "stretched" solid effect. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

High-frequency noise characterization of graphene field effect transistors on SiC substrates

NASA Astrophysics Data System (ADS)

Yu, C.; He, Z. Z.; Song, X. B.; Liu, Q. B.; Dun, S. B.; Han, T. T.; Wang, J. J.; Zhou, C. J.; Guo, J. C.; Lv, Y. J.; Cai, S. J.; Feng, Z. H.

2017-07-01

Considering its high carrier mobility and high saturation velocity, a low-noise amplifier is thought of as being the most attractive analogue application of graphene field-effect transistors. The noise performance of graphene field-effect transistors at frequencies in the K-band remains unknown. In this work, the noise parameters of a graphene transistor are measured from 10 to 26 GHz and noise models are built with the data. The extrinsic minimum noise figure for a graphene transistor reached 1.5 dB, and the intrinsic minimum noise figure was as low as 0.8 dB at a frequency of 10 GHz, which were comparable with the results from tests on Si CMOS and started to approach those for GaAs and InP transistors. Considering the short development time, the current results are a significant step forward for graphene transistors and show their application potential in high-frequency electronics.

The word frequency effect during sentence reading: A linear or nonlinear effect of log frequency?

PubMed

White, Sarah J; Drieghe, Denis; Liversedge, Simon P; Staub, Adrian

2016-10-20

The effect of word frequency on eye movement behaviour during reading has been reported in many experimental studies. However, the vast majority of these studies compared only two levels of word frequency (high and low). Here we assess whether the effect of log word frequency on eye movement measures is linear, in an experiment in which a critical target word in each sentence was at one of three approximately equally spaced log frequency levels. Separate analyses treated log frequency as a categorical or a continuous predictor. Both analyses showed only a linear effect of log frequency on the likelihood of skipping a word, and on first fixation duration. Ex-Gaussian analyses of first fixation duration showed similar effects on distributional parameters in comparing high- and medium-frequency words, and medium- and low-frequency words. Analyses of gaze duration and the probability of a refixation suggested a nonlinear pattern, with a larger effect at the lower end of the log frequency scale. However, the nonlinear effects were small, and Bayes Factor analyses favoured the simpler linear models for all measures. The possible roles of lexical and post-lexical factors in producing nonlinear effects of log word frequency during sentence reading are discussed.

Opposite effects of high- and low-frequency transcranial random noise stimulation probed with visual motion adaptation

PubMed Central

Campana, Gianluca; Camilleri, Rebecca; Moret, Beatrice; Ghin, Filippo; Pavan, Andrea

2016-01-01

Transcranial random noise stimulation (tRNS) is a recent neuro-modulation technique whose effects at both behavioural and neural level are still debated. Here we employed the well-known phenomenon of motion after-effect (MAE) in order to investigate the effects of high- vs. low-frequency tRNS on motion adaptation and recovery. Participants were asked to estimate the MAE duration following prolonged adaptation (20 s) to a complex moving pattern, while being stimulated with either sham or tRNS across different blocks. Different groups were administered with either high- or low-frequency tRNS. Stimulation sites were either bilateral human MT complex (hMT+) or frontal areas. The results showed that, whereas no effects on MAE duration were induced by stimulating frontal areas, when applied to the bilateral hMT+, high-frequency tRNS caused a significant decrease in MAE duration whereas low-frequency tRNS caused a significant corresponding increase in MAE duration. These findings indicate that high- and low-frequency tRNS have opposed effects on the adaptation-dependent unbalance between neurons tuned to opposite motion directions, and thus on neuronal excitability. PMID:27934947

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jiang, S. D.; Eggers, T.; Thiabgoh, O.

Understanding the relationship between the surface conditions and giant magneto-impedance (GMI) in Co-rich melt-extracted microwires is key to optimizing their magnetic responses for magnetic sensor applications. The surface magnetic domain structure (SMDS) parameters of ~45 μm diameter Co 69.25Fe 4.25Si 13B 13.5-xZr x (x = 0, 1, 2, 3) microwires, including the magnetic domain period (d) and surface roughness (Rq) as extracted from the magnetic force microscopy (MFM) images, have been correlated with GMI in the range 1–1000 MHz. It was found that substitution of B with 1 at. % Zr increased d of the base alloy from 729 tomore » 740 nm while retaining Rq from ~1 nm to ~3 nm. A tremendous impact on the GMI ratio was found, increasing the ratio from ~360% to ~490% at an operating frequency of 40 MHz. Further substitution with Zr decreased the high frequency GMI ratio, which can be understood by the significant increase in surface roughness evident by force microscopy. Lastly, this study demonstrates the application of the domain period and surface roughness found by force microscopy to the interpretation of the GMI in Co-rich microwires.« less

Relating surface roughness and magnetic domain structure to giant magneto-impedance of Co-rich melt-extracted microwires

DOE PAGES

Jiang, S. D.; Eggers, T.; Thiabgoh, O.; ...

2017-04-11

Understanding the relationship between the surface conditions and giant magneto-impedance (GMI) in Co-rich melt-extracted microwires is key to optimizing their magnetic responses for magnetic sensor applications. The surface magnetic domain structure (SMDS) parameters of ~45 μm diameter Co 69.25Fe 4.25Si 13B 13.5-xZr x (x = 0, 1, 2, 3) microwires, including the magnetic domain period (d) and surface roughness (Rq) as extracted from the magnetic force microscopy (MFM) images, have been correlated with GMI in the range 1–1000 MHz. It was found that substitution of B with 1 at. % Zr increased d of the base alloy from 729 tomore » 740 nm while retaining Rq from ~1 nm to ~3 nm. A tremendous impact on the GMI ratio was found, increasing the ratio from ~360% to ~490% at an operating frequency of 40 MHz. Further substitution with Zr decreased the high frequency GMI ratio, which can be understood by the significant increase in surface roughness evident by force microscopy. Lastly, this study demonstrates the application of the domain period and surface roughness found by force microscopy to the interpretation of the GMI in Co-rich microwires.« less

Effective High-Frequency Permeability of Compacted Metal Powders

NASA Astrophysics Data System (ADS)

Volkovskaya, I. I.; Semenov, V. E.; Rybakov, K. I.

2018-03-01

We propose a model for determination of the effective complex permeability of compacted metal-powder media. It is based on the equality of the magnetic moment in a given volume of the media with the desired effective permeability to the total magnetic moment of metal particles in the external high-frequency magnetic field, which arises due to excitation of electric eddy currents in the particles. Calculations within the framework of the proposed model allow us to refine the values of the real and imaginary components of the permeability of metal powder compacts in the microwave band. The conditions of applicability of the proposed model are formulated, and their fulfillment is verified for metal powder compacts in the microwave and millimeter wavelength bands.

Defining the Metabolic Functions and Roles in Virulence of the rpoN1 and rpoN2 Genes in Ralstonia solanacearum GMI1000.

PubMed

Lundgren, Benjamin R; Connolly, Morgan P; Choudhary, Pratibha; Brookins-Little, Tiffany S; Chatterjee, Snigdha; Raina, Ramesh; Nomura, Christopher T

2015-01-01

The alternative sigma factor RpoN is a unique regulator found among bacteria. It controls numerous processes that range from basic metabolism to more complex functions such as motility and nitrogen fixation. Our current understanding of RpoN function is largely derived from studies on prototypical bacteria such as Escherichia coli. Bacillus subtilis and Pseudomonas putida. Although the extent and necessity of RpoN-dependent functions differ radically between these model organisms, each bacterium depends on a single chromosomal rpoN gene to meet the cellular demands of RpoN regulation. The bacterium Ralstonia solanacearum is often recognized for being the causative agent of wilt disease in crops, including banana, peanut and potato. However, this plant pathogen is also one of the few bacterial species whose genome possesses dual rpoN genes. To determine if the rpoN genes in this bacterium are genetically redundant and interchangeable, we constructed and characterized ΔrpoN1, ΔrpoN2 and ΔrpoN1 ΔrpoN2 mutants of R. solanacearum GMI1000. It was found that growth on a small range of metabolites, including dicarboxylates, ethanol, nitrate, ornithine, proline and xanthine, were dependent on only the rpoN1 gene. Furthermore, the rpoN1 gene was required for wilt disease on tomato whereas rpoN2 had no observable role in virulence or metabolism in R. solanacearum GMI1000. Interestingly, plasmid-based expression of rpoN2 did not fully rescue the metabolic deficiencies of the ΔrpoN1 mutants; full recovery was specific to rpoN1. In comparison, only rpoN2 was able to genetically complement a ΔrpoN E. coli mutant. These results demonstrate that the RpoN1 and RpoN2 proteins are not functionally equivalent or interchangeable in R. solanacearum GMI1000.

Assimilating All-Sky GPM Microwave Imager(GMI) Radiance Data in NASA GEOS-5 System for Global Cloud and Precipitation Analyses

NASA Astrophysics Data System (ADS)

Kim, M. J.; Jin, J.; McCarty, W.; Todling, R.; Holdaway, D. R.; Gelaro, R.

2014-12-01

The NASA Global Modeling and Assimilation Office (GMAO) works to maximize the impact of satellite observations in the analysis and prediction of climate and weather through integrated Earth system modeling and data assimilation. To achieve this goal, the GMAO undertakes model and assimilation development, generates products to support NASA instrument teams and the NASA Earth science program. Currently Atmospheric Data Assimilation System (ADAS) in the Goddard Earth Observing System Model, Version 5(GEOS-5) system combines millions of observations and short-term forecasts to determine the best estimate, or analysis, of the instantaneous atmospheric state. However, ADAS has been geared towards utilization of observations in clear sky conditions and the majority of satellite channel data affected by clouds are discarded. Microwave imager data from satellites can be a significant source of information for clouds and precipitation but the data are presently underutilized, as only surface rain rates from the Tropical Rainfall Measurement Mission (TRMM) Microwave Imager (TMI) are assimilated with small weight assigned in the analysis process. As clouds and precipitation often occur in regions with high forecast sensitivity, improvements in the temperature, moisture, wind and cloud analysis of these regions are likely to contribute to significant gains in numerical weather prediction accuracy. This presentation is intended to give an overview of GMAO's recent progress in assimilating the all-sky GPM Microwave Imager (GMI) radiance data in GEOS-5 system. This includes development of various new components to assimilate cloud and precipitation affected data in addition to data in clear sky condition. New observation operators, quality controls, moisture control variables, observation and background error models, and a methodology to incorporate the linearlized moisture physics in the assimilation system are described. In addition preliminary results showing impacts of

Effects of high frequency current in welding aluminum alloy 6061

NASA Technical Reports Server (NTRS)

Fish, R. E.

1968-01-01

Uncontrolled high frequency current causes cracking in the heat-affected zone of aluminum alloy 6061 weldments during tungsten inert gas ac welding. Cracking developed when an improperly adjusted superimposed high frequency current was agitating the semimolten metal in the areas of grain boundary.

The relative immunity of high-frequency transposed stimuli to low-frequency binaural interference

NASA Astrophysics Data System (ADS)

Bernstein, Leslie R.; Trahiotis, Constantine

2004-05-01

We have recently demonstrated that high-frequency transposed stimuli, having envelopes designed to provide high-frequency channels with information similar to that normally available in only low-frequency channels, yield threshold-ITDs and extents of laterality comparable to those obtained with conventional low-frequency stimuli. This enhanced potency of ITDs conveyed by high-frequency transposed stimuli, as compared to conventional high-frequency stimuli, suggested to us that ITDs conveyed by transposed stimuli might be relatively immune to the presence of low-frequency binaural interferers. To investigate this issue, threshold-ITDs and extents of laterality were measured with a variety of conventional and transposed targets centered at 4 kHz. The targets were presented either in the presence or absence of a simultaneously gated diotic noise centered at 500 Hz, the interferer. As expected, the presence of the low-frequency interferer resulted in substantially elevated threshold-ITDs and reduced extents of laterality for the conventional high-frequency stimuli. In contrast, these interference effects were either greatly attenuated or absent for ITDs conveyed by the high-frequency transposed targets. The results will be discussed in the context of current models of binaural interference. [Work supported by NIH DC 04147, NIH DC04073, NIH DC 002304.

The effect of sampling rate and anti-aliasing filters on high-frequency response spectra

USGS Publications Warehouse

Boore, David M.; Goulet, Christine

2013-01-01

The most commonly used intensity measure in ground-motion prediction equations is the pseudo-absolute response spectral acceleration (PSA), for response periods from 0.01 to 10 s (or frequencies from 0.1 to 100 Hz). PSAs are often derived from recorded ground motions, and these motions are usually filtered to remove high and low frequencies before the PSAs are computed. In this article we are only concerned with the removal of high frequencies. In modern digital recordings, this filtering corresponds at least to an anti-aliasing filter applied before conversion to digital values. Additional high-cut filtering is sometimes applied both to digital and to analog records to reduce high-frequency noise. Potential errors on the short-period (high-frequency) response spectral values are expected if the true ground motion has significant energy at frequencies above that of the anti-aliasing filter. This is especially important for areas where the instrumental sample rate and the associated anti-aliasing filter corner frequency (above which significant energy in the time series is removed) are low relative to the frequencies contained in the true ground motions. A ground-motion simulation study was conducted to investigate these effects and to develop guidance for defining the usable bandwidth for high-frequency PSA. The primary conclusion is that if the ratio of the maximum Fourier acceleration spectrum (FAS) to the FAS at a frequency fsaa corresponding to the start of the anti-aliasing filter is more than about 10, then PSA for frequencies above fsaa should be little affected by the recording process, because the ground-motion frequencies that control the response spectra will be less than fsaa . A second topic of this article concerns the resampling of the digital acceleration time series to a higher sample rate often used in the computation of short-period PSA. We confirm previous findings that sinc-function interpolation is preferred to the standard practice of using

Update on the effects of graded motor imagery and mirror therapy on complex regional pain syndrome type 1: A systematic review.

PubMed

Méndez-Rebolledo, Guillermo; Gatica-Rojas, Valeska; Torres-Cueco, Rafael; Albornoz-Verdugo, María; Guzmán-Muñoz, Eduardo

2017-01-01

Graded motor imagery (GMI) and mirror therapy (MT) is thought to improve pain in patients with complex regional pain syndrome (CRPS) types 1 and 2. However, the evidence is limited and analysis are not independent between types of CRPS. The purpose of this review was to analyze the effects of GMI and MT on pain in independent groups of patients with CRPS types 1 and 2. Searches for literature published between 1990 and 2016 were conducted in databases. Randomized controlled trials that compared GMI or MT with other treatments for CRPS types 1 and 2 were included. Six articles met the inclusion criteria and were classified from moderate to high quality. The total sample was composed of 171 participants with CRPS type 1. Three studies presented GMI with 3 components and three studies only used the MT. The studies were heterogeneous in terms of sample size and the disorders that triggered CRPS type 1. There were no trials that included participants with CRPS type 2. GMI and MT can improve pain in patients with CRPS type 1; however, there is not sufficient evidence to recommend these therapies over other treatments given the small size and heterogeneity of the studied population.

Signatures of Hydrometeor Species from Airborne Passive Microwave Data for Frequencies 10-183 GHz

NASA Technical Reports Server (NTRS)

Cecil, Daniel J.; Leppert, Kenneth, II

2014-01-01

There are 2 basic precipitation retrieval methods using passive microwave measurements: (1) Emission-based: Based on the tendency of liquid precipitation to cause an increase in brightness temperature (BT) primarily at frequencies below 22 GHz over a radiometrically cold background, often an ocean background (e.g., Spencer et al. 1989; Adler et al. 1991; McGaughey et al. 1996); and (2) Scattering-based: Based on the tendency of precipitation-sized ice to scatter upwelling radiation, thereby reducing the measured BT over a relatively warmer (usually land) background at frequencies generally 37 GHz (e.g., Spencer et al. 1989; Smith et al. 1992; Ferraro and Marks 1995). Passive microwave measurements have also been used to detect intense convection (e.g., Spencer and Santek 1985) and for the detection of hail (e.g., Cecil 2009; Cecil and Blankenship 2012; Ferraro et al. 2014). The Global Precipitation Measurement (GPM) mission expands upon the successful Tropical Rainfall Measurement Mission program to provide global rainfall and snowfall observations every 3 hours (Hou et al. 2014). One of the instruments on board the GPM Core Observatory is the GPM Microwave Imager (GMI) which is a conically-scanning microwave radiometer with 13 channels ranging from 10-183 GHz. Goal of this study: Determine the signatures of various hydrometeor species in terms of BTs measured at frequencies used by GMI by using data collected on 3 case days (all having intense/severe convection) during the Mid-latitude Continental Convective Clouds Experiment conducted over Oklahoma in 2011.

High-frequency intrinsic dynamics of the electrocaloric effect from direct atomistic simulations

NASA Astrophysics Data System (ADS)

Lisenkov, S.; Ponomareva, I.

2018-05-01

We propose a computational methodology capable of harvesting isothermal heat and entropy change in molecular dynamics simulations. The methodology is applied to study high-frequency dynamics of the electrocaloric effect (ECE) in ferroelectric PbTiO3. ECE is associated with a reversible change in temperature under adiabatic application of electric field or with a reversible change in entropy under isothermal application of the electric field. Accurate assessment of electrocaloric performance requires the knowledge of three quantities: isothermal heat, isothermal entropy change, and adiabatic temperature change. Our methodology allows computations of all these quantities directly, that is, without restoring to the reversible thermodynamical models. Consequently, it captures both reversible and irreversible effects, which is critical for ECE simulations. The approach is well suited to address the dynamics of the ECE, which so far remains underexplored. We report the following basic features of the intrinsic dynamics of ECE: (i) the ECE is independent of the electric field frequency, rate of application, or field profile; (ii) the effect persists up to the frequencies associated with the onset of dielectric losses and deteriorates from there due to the creation of irreversible entropy; and (iii) in the vicinity of the phase transition and in the paraelectric phase the onset of irreversible dynamics occurs at lower frequency as compared to the ferroelectric phase. The latter is attributed to lower intrinsic soft-mode frequencies and and larger losses in the paraelectric phase.

High power single-frequency and frequency-doubled laser with active compensation for the thermal lens effect of terbium gallium garnet crystal.

PubMed

Yin, Qiwei; Lu, Huadong; Su, Jing; Peng, Kunchi

2016-05-01

The thermal lens effect of terbium gallium garnet (TGG) crystal in a high power single-frequency laser severely limits the output power and the beam quality of the laser. By inserting a potassium dideuterium phosphate (DKDP) slice with negative thermo-optical coefficient into the laser resonator, the harmful influence of the thermal lens effect of the TGG crystal can be effectively mitigated. Using this method, the stable range of the laser is broadened, the bistability phenomenon of the laser during the process of changing the pump power is completely eliminated, the highest output power of an all-solid-state continuous-wave intracavity-frequency-doubling single-frequency laser at 532 nm is enhanced to 30.2 W, and the beam quality of the laser is significantly improved.

Giant magneto-impedance and stress-impedance effects of microwire composites for sensing applications

NASA Astrophysics Data System (ADS)

Qin, F. X.; Peng, H. X.; Popov, V. V.; Phan, M. H.

2011-02-01

Composites consisting of glass-coated amorphous microwire Co 68.59Fe 4.84Si 12.41B 14.16 and 913 E-glass prepregs were designed and fabricated. The influences of tensile stress, annealing and number of composite layers on the giant magneto-impedance (GMI) and giant stress-impedance (GSI) effects in these composites were investigated systematically. It was found that the application of tensile stress along the microwire axis or an increase in the number of composite layers reduced the GMI effect and increased the circular anisotropy field, while the annealing treatment had a reverse effect. The value of matrix-wire interfacial stress calculated via the GMI profiles coincided with the value of the applied effective tensile stress to yield similar GMI profiles. Enhancement of the GSI effect was achieved in the composites relative to their single microwire inclusion. These findings are important for the development of functional microwire-based composites for magnetic- and stress-sensing applications. They also open up a new route for probing the interfacial stress in fibre-reinforced polymer (FRP) composites.

Peak high-frequency HRV and peak alpha frequency higher in PTSD.

PubMed

Wahbeh, Helané; Oken, Barry S

2013-03-01

Posttraumatic stress disorder (PTSD) is difficult to treat and current PTSD treatments are not effective for all people. Despite limited evidence for its efficacy, some clinicians have implemented biofeedback for PTSD treatment. As a first step in constructing an effective biofeedback treatment program, we assessed respiration, electroencephalography (EEG) and heart rate variability (HRV) as potential biofeedback parameters for a future clinical trial. This cross-sectional study included 86 veterans; 59 with and 27 without PTSD. Data were collected on EEG measures, HRV, and respiration rate during an attentive resting state. Measures were analyzed to assess sensitivity to PTSD status and the relationship to PTSD symptoms. Peak alpha frequency was higher in the PTSD group (F(1,84) = 6.14, p = 0.01). Peak high-frequency HRV was lower in the PTSD group (F(2,78) = 26.5, p < 0.00005) when adjusting for respiration rate. All other EEG and HRV measures and respiration were not different between groups. Peak high-frequency HRV and peak alpha frequency are sensitive to PTSD status and may be potential biofeedback parameters for future PTSD clinical trials.

Use of coincident radar and radiometer observations from GPM, ATMS, and CloudSat for global spaceborne snowfall observation assessment

NASA Astrophysics Data System (ADS)

Panegrossi, Giulia; Casella, Daniele; Sanò, Paolo; Cinzia Marra, Anna; Dietrich, Stefano; Johnson, Benjamin T.; Kulie, Mark S.

2017-04-01

the precipitating snowfall mass), mostly because of sensitivity limits of the DPR and secondly because of the effect of side lobe clutter. We will show that improved DPR detection capabilities (> 50%) of the snowfall mass can be achieved by optimally combining Ku-band and Ka-band measured reflectivity and exploiting the weak signals related to snowfall. ATMS-CPR, GMI-CPR, and GMI-DPR coincident observations have been analyzed in order to study the multichannel brightness temperature signal related to snowfall. The main results of this study show that the high frequency channels (and the 183 GHz band channels in particular) can be successfully used to identify snowfall, but results depend strongly on proper identification of surface background and proper estimation of integrated water vapor content. In this context a new algorithm for surface classification using primarily ATMS (and GMI) low frequency channels, and identifying different snow-covered land surfaces and ice or broken-ice over ocean, is proposed and will be presented.

High vs. Low Frequency Stimulation Effects on Fine Motor Control in Chronic Hemiplegia: A Pilot Study

PubMed Central

Doucet, Barbara M.; Griffin, Lisa

2014-01-01

Introduction The optimal parameters of neuromuscular electrical stimulation (NMES) for recovery of hand function following stroke are not known. This clinical pilot study examined whether higher or lower frequencies are more effective for improving fine motor control of the hand in a chronic post-stroke population. Methods A one-month, 4x/week in-home regimen of either a high frequency (40Hz) or low frequency (20Hz) NMES program was applied to the hemiplegic thenar muscles of 16 persons with chronic stroke. Participants were identified a priori as having a low level of function (LF) or a high level of function (HF). Outcome measures of strength, dexterity, and endurance were measured before and after participation in the regimen. Results LF subjects showed no significant changes with either the high or the low frequency NMES regimen. HF subjects showed significant changes in strength, dexterity and endurance. Within this group, higher frequencies of stimulation yielded strength gains and increased motor activation; lower frequencies impacted dexterity and endurance. Conclusions The results suggest that higher frequencies of stimulation could be more effective in improving strength and motor activation properties and that lower frequencies may impact coordination and endurance changes; results also indicate that persons with a higher functional level of recovery may respond more favorably to NMES regimens, but further study with larger patient groups is warranted. PMID:23893829

High-frequency, high-intensity photoionization

NASA Astrophysics Data System (ADS)

Reiss, H. R.

1996-02-01

Two analytical methods for computing ionization by high-frequency fields are compared. Predicted ionization rates compare well, but energy predictions for the onset of ionization differ radically. The difference is shown to arise from the use of a transformation in one of the methods that alters the zero from which energy is measured. This alteration leads to an apparent energy threshold for ionization that can, especially in the stabilization regime, differ strongly from the laboratory measurement. It is concluded that channel closings in intense-field ionization can occur at high as well as low frequencies. It is also found that the stabilization phenomenon at high frequencies, very prominent for hydrogen, is absent in a short-range potential.

Atmospheric and Fog Effects on Ultra-Wide Band Radar Operating at Extremely High Frequencies.

PubMed

Balal, Nezah; Pinhasi, Gad A; Pinhasi, Yosef

2016-05-23

The wide band at extremely high frequencies (EHF) above 30 GHz is applicable for high resolution directive radars, resolving the lack of free frequency bands within the lower part of the electromagnetic spectrum. Utilization of ultra-wideband signals in this EHF band is of interest, since it covers a relatively large spectrum, which is free of users, resulting in better resolution in both the longitudinal and transverse dimensions. Noting that frequencies in the millimeter band are subjected to high atmospheric attenuation and dispersion effects, a study of the degradation in the accuracy and resolution is presented. The fact that solid-state millimeter and sub-millimeter radiation sources are producing low power, the method of continuous-wave wideband frequency modulation becomes the natural technique for remote sensing and detection. Millimeter wave radars are used as complementary sensors for the detection of small radar cross-section objects under bad weather conditions, when small objects cannot be seen by optical cameras and infrared detectors. Theoretical analysis for the propagation of a wide "chirped" Frequency-Modulated Continuous-Wave (FMCW) radar signal in a dielectric medium is presented. It is shown that the frequency-dependent (complex) refractivity of the atmospheric medium causes distortions in the phase of the reflected signal, introducing noticeable errors in the longitudinal distance estimations, and at some frequencies may also degrade the resolution.

Atmospheric and Fog Effects on Ultra-Wide Band Radar Operating at Extremely High Frequencies

PubMed Central

Balal, Nezah; Pinhasi, Gad A.; Pinhasi, Yosef

2016-01-01

The wide band at extremely high frequencies (EHF) above 30 GHz is applicable for high resolution directive radars, resolving the lack of free frequency bands within the lower part of the electromagnetic spectrum. Utilization of ultra-wideband signals in this EHF band is of interest, since it covers a relatively large spectrum, which is free of users, resulting in better resolution in both the longitudinal and transverse dimensions. Noting that frequencies in the millimeter band are subjected to high atmospheric attenuation and dispersion effects, a study of the degradation in the accuracy and resolution is presented. The fact that solid-state millimeter and sub-millimeter radiation sources are producing low power, the method of continuous-wave wideband frequency modulation becomes the natural technique for remote sensing and detection. Millimeter wave radars are used as complementary sensors for the detection of small radar cross-section objects under bad weather conditions, when small objects cannot be seen by optical cameras and infrared detectors. Theoretical analysis for the propagation of a wide “chirped” Frequency-Modulated Continuous-Wave (FMCW) radar signal in a dielectric medium is presented. It is shown that the frequency-dependent (complex) refractivity of the atmospheric medium causes distortions in the phase of the reflected signal, introducing noticeable errors in the longitudinal distance estimations, and at some frequencies may also degrade the resolution. PMID:27223286

High-efficiency water-loaded microwave antenna in ultra-high-frequency band

NASA Astrophysics Data System (ADS)

Gong, Zilun; Bartone, Chris; Yang, Fuyi; Yao, Jie

2018-03-01

High-index dielectrics are widely used in microwave antennas to control the radiation characteristics. Liquid water, with a high dielectric index at microwave frequency, is an interesting material to achieving tunable functionalities. Here, we demonstrate a water-loaded microwave antenna system that has high loss-tolerance and wideband tunability enabled by fluidity. Our simulation and experimental results show that the resonance frequency can be effectively tuned by the size of loading water. Furthermore, the antenna systems with water loading can achieve high radiation efficiency (>90%) in the ultra-high-frequency (0.3-3 GHz) band. This work brings about opportunities in realistic tunable microwave antenna designs enabled by liquid.

Effect of Endurance Training on The Lactate and Glucose Minimum Intensities

PubMed Central

Junior, Pedro B.; de Andrade, Vitor L.; Campos, Eduardo Z.; Kalva-Filho, Carlos A.; Zagatto, Alessandro M.; de Araújo, Gustavo G.; Papoti, Marcelo

2018-01-01

Due to the controversy about the sensitive of lactate minimum intensity (LMI) to training and the need to develop other tool for aerobic fitness evaluation, the purpose of this study was to analyze the sensitivity of glucose minimum intensity (GMI) and LMI to endurance training. Eight trained male cyclists (21.4 ± 1.9 years, 67.6 ± 7.5 kg and 1.72 ± 0.10 m) were evaluated twice, before and after 12 weeks of training. GMI and LMI were calculated, respectively, by the lowest blood glucose and lactate values attained during an incremental test performed after a hyperlactemia induction, and VO2max was determined during standard incremental effort. The training was prescribed in three different zones and controlled by heart rate (HR). The training distribution was equivalent to 59.7%, 25.0% and 15.3% below, at and above anaerobic threshold HR respectively. The anaerobic threshold evaluated by GMI and LMI improvement 9.89 ± 4.35% and 10.28 ± 9.89 respectively, after training, but the VO2max 2.52 ± 1.81%. No differences were found between GMI and LMI in pre (218.2 ± 22.1 vs 215.0 ± 18.6 W) and post (240.6 ± 22.9 vs 237.5 ± 18.8 W) training situations. LMI and GMI were sensitive to 12-week aerobic training in cyclist; thus, both protocols can be used to assess aerobic adaptation, athletes diagnostic and prescribe training. Key points The lactate and glucose minimum intensities (GMI) can be used for monitoring training effects on cyclists Although both GMI and lactate minimum intensities are important index of aerobic fitness, they cannot be used to determine aerobic fitness. The polarized training was effective for improvements of maximal oxygen uptake on trained cyclists. PMID:29535585

Enhancement of Giant Magneto-Impedance in Series Co-Rich Microwires for Low-Field Sensing Applications

NASA Astrophysics Data System (ADS)

Jiang, S. D.; Eggers, T.; Thiabgoh, O.; Xing, D. W.; Fang, W. B.; Sun, J. F.; Srikanth, H.; Phan, M. H.

2018-02-01

Two soft ferromagnetic Co68.25Fe4.25Si12.25B15.25 microwires with the same diameter of 50 ± 1 μm but different fabrication processes were placed in series and in parallel circuit configurations to investigate their giant magneto-impedance (GMI) responses in a frequency range of 1-100 MHz for low-field sensing applications. We show that, while the low-field GMI response is significantly reduced in the parallel configuration, it is greatly enhanced in the series connection. These results suggest that a highly sensitive GMI sensor can be designed by arranging multi-wires in a saw-shaped fashion to optimize the sensing area, and soldered together in series connection to maintain the excellent magnetic field sensitivity.

Radicals and Reservoirs in the GMI Chemistry and Transport Model: Comparison to Measurements

NASA Technical Reports Server (NTRS)

Douglass, Anne R.; Stolarski, Richard S.; Strahan, Susan E.; Connell, Peter S.

2004-01-01

We have used a three-dimensional chemistry and transport model (CTM), developed under the Global Modeling Initiative (GMI), to carry out two simulations of the composition of the stratosphere under changing halogen loading for 1995 through 2030. The two simulations differ only in that one uses meteorological fields from a general circulation model while the other uses meteorological fields from a data assimilation system. A single year's winds and temperatures are repeated for each 36-year simulation. We compare results from these two simulations with an extensive collection of data from satellite and ground-based measurements for 1993-2000. Comparisons of simulated fields with observations of radical and reservoir species for some of the major ozone-destroying compounds are of similar quality for both simulations. Differences in the upper stratosphere, caused by transport of total reactive nitrogen and methane, impact the balance among the ozone loss processes and the sensitivity of the two simulations to the change in composition.

Peak High-Frequency HRV and Peak Alpha Frequency Higher in PTSD

PubMed Central

Oken, Barry S.

2012-01-01

Posttraumatic stress disorder (PTSD) is difficult to treat and current PTSD treatments are not effective for all people. Despite limited evidence for its efficacy, some clinicians have implemented biofeedback for PTSD treatment. As a first step in constructing an effective biofeedback treatment program, we assessed respiration, electroencephalography (EEG) and heart rate variability (HRV) as potential biofeedback parameters for a future clinical trial. This cross-sectional study included 86 veterans; 59 with and 27 without PTSD. Data were collected on EEG measures, HRV, and respiration rate during an attentive resting state. Measures were analyzed to assess sensitivity to PTSD status and the relationship to PTSD symptoms. Peak alpha frequency was higher in the PTSD group (F(1,84) = 6.14, p = 0.01). Peak high-frequency HRV was lower in the PTSD group (F(2,78) = 26.5, p<0.00005) when adjusting for respiration rate. All other EEG and HRV measures and respiration were not different between groups. Peak high-frequency HRV and peak alpha frequency are sensitive to PTSD status and may be potential biofeedback parameters for future PTSD clinical trials. PMID:23178990

[Antitumor effect of low-intensity extremely high-frequency electromagnetic radiation on a model of solid Ehrlich carcinoma].

PubMed

Gapeev, A B; Shved, D M; Mikhaĭlik, E N; Korystov, Iu N; Levitman, M Kh; Shaposhnikova, V V; Sadovnikov, V B; Alekhin, A I; Goncharov, N G; Chemeris, N K

2009-01-01

The influence of different exposure regimes of low-intensity extremely high-frequency electromagnetic radiation on the growth rate of solid Ehrlich carcinoma in mice has been studied. It was shown that, at an optimum repetition factor of exposure (20 min daily for five consecutive days after the tumor inoculation), there is a clearly pronounced frequency dependence of the antitumor effect. The analysis of experimental data indicates that the mechanisms of antitumor effects of the radiation may be related to the modification of the immune status of the organism. The results obtained show that extremely high-frequency electromagnetic radiation at a proper selection of exposure regimes can result in distinct and stable antitumor effects.

Evaluation of ozone hindcasts: optimal data sets to use, and results from simulations with the GMI model for 1990-2010.

NASA Astrophysics Data System (ADS)

Logan, J. A.; Megretskaia, I.; Liu, J.; Rodriguez, J. M.; Strahan, S. E.; Damon, M.; Steenrod, S. D.

2012-12-01

Simulations of atmospheric composition in the recent past (hindcasts) are a valuable tool for determining the causes of interannual variability (IAV) and trends in tropospheric ozone, including factors such as anthropogenic emissions, biomass burning, stratospheric input, and variability in meteorology. We will review the ozone data sets (balloon, satellite, and surface) that are the most reliable for evaluating hindcasts, and demonstrate their application with the GMI model. The GMI model is driven by the GEOS-5/MERRA reanalysis and includes both stratospheric and tropospheric chemistry. Preliminary analysis of a simulation for 1990-2010 using constant fossil fuel emissions is promising. The model reproduces the recent interannual variability (IAV) in ozone in the lowermost stratosphere seen in MLS and sonde data, as well as the IAV seen in sonde data in the lower stratosphere since 1995, and captures much of the IAV and short-term trends in surface ozone at remote sites, showing the influence of variability in dynamics. There was considerable IAV in ozone in the lowermost stratosphere in the Aura period, but almost none at European alpine sites in winter/spring, when ozone at 150 hPa has been shown to be correlated with that at 700 hPa in earlier years. The model matches the IAV in alpine ozone in Europe in July-September, including the high values in heat-waves, showing the role of variability in meteorology. A focus on IAV in each season is essential. The model matches IAV in MLS in the upper troposphere, TES tropical ozone, and the tropospheric ozone column (OMI/MLS) the best in tSropical regions controlled by ENSO related changes in dynamics. This study, combined with sensitivity simulations with changes to emissions, and simulations with passive tracers (see Abstract by Rodriguez et al. Session A76), lays the foundations for assessment of the mechanisms that have influenced tropospheric ozone in the past two decades.

Auditory word recognition: extrinsic and intrinsic effects of word frequency.

PubMed

Connine, C M; Titone, D; Wang, J

1993-01-01

Two experiments investigated the influence of word frequency in a phoneme identification task. Speech voicing continua were constructed so that one endpoint was a high-frequency word and the other endpoint was a low-frequency word (e.g., best-pest). Experiment 1 demonstrated that ambiguous tokens were labeled such that a high-frequency word was formed (intrinsic frequency effect). Experiment 2 manipulated the frequency composition of the list (extrinsic frequency effect). A high-frequency list bias produced an exaggerated influence of frequency; a low-frequency list bias showed a reverse frequency effect. Reaction time effects were discussed in terms of activation and postaccess decision models of frequency coding. The results support a late use of frequency in auditory word recognition.

High-frequency applications of high-temperature superconductor thin films

NASA Astrophysics Data System (ADS)

Klein, N.

2002-10-01

High-temperature superconducting thin films offer unique properties which can be utilized for a variety of high-frequency device applications in many areas related to the strongly progressing market of information technology. One important property is an exceptionally low level of microwave absorption at temperatures attainable with low power cryocoolers. This unique property has initiated the development of various novel type of microwave devices and commercialized subsystems with special emphasis on application in advanced microwave communication systems. The second important achievement related to efforts in oxide thin and multilayer technology was the reproducible fabrication of low-noise Josephson junctions in high-temperature superconducting thin films. As a consequence of this achievement, several novel nonlinear high-frequency devices, most of them exploiting the unique features of the ac Josephson effect, have been developed and found to exhibit challenging properties to be utilized in basic metrology and Terahertz technology. On the longer timescale, the achievements in integrated high-temperature superconductor circuit technology may offer a strong potential for the development of digital devices with possible clock frequencies in the range of 100 GHz.

Carbon nanotube transistor based high-frequency electronics

NASA Astrophysics Data System (ADS)

Schroter, Michael

At the nanoscale carbon nanotubes (CNTs) have higher carrier mobility and carrier velocity than most incumbent semiconductors. Thus CNT based field-effect transistors (FETs) are being considered as strong candidates for replacing existing MOSFETs in digital applications. In addition, the predicted high intrinsic transit frequency and the more recent finding of ways to achieve highly linear transfer characteristics have inspired investigations on analog high-frequency (HF) applications. High linearity is extremely valuable for an energy efficient usage of the frequency spectrum, particularly in mobile communications. Compared to digital applications, the much more relaxed constraints for CNT placement and lithography combined with already achieved operating frequencies of at least 10 GHz for fabricated devices make an early entry in the low GHz HF market more feasible than in large-scale digital circuits. Such a market entry would be extremely beneficial for funding the development of production CNTFET based process technology. This talk will provide an overview on the present status and feasibility of HF CNTFET technology will be given from an engineering point of view, including device modeling, experimental results, and existing roadblocks. Carbon nanotube transistor based high-frequency electronics.

High-current, high-frequency capacitors

NASA Technical Reports Server (NTRS)

Renz, D. D.

1983-01-01

The NASA Lewis high-current, high-frequency capacitor development program was conducted under a contract with Maxwell Laboratories, Inc., San Diego, California. The program was started to develop power components for space power systems. One of the components lacking was a high-power, high-frequency capacitor. Some of the technology developed in this program may be directly usable in an all-electric airplane. The materials used in the capacitor included the following: the film is polypropylene, the impregnant is monoisopropyl biphenyl, the conductive epoxy is Emerson and Cuming Stycast 2850 KT, the foil is aluminum, the case is stainless steel (304), and the electrode is a modified copper-ceramic.

Analysis and Correction of Diffraction Effect on the B/A Measurement at High Frequencies

NASA Astrophysics Data System (ADS)

Zhang, Dong; Gong, Xiu-Fen; Liu, Xiao-Zhou; Kushibiki, Jun-ichi; Nishino, Hideo

2004-01-01

A numerical method is developed to analyse and to correct the diffraction effect in the measurement of acoustic nonlinearity parameter B/A at high frequencies. By using the KZK nonlinear equation and the superposition approach of Gaussian beams, an analytical model is derived to describe the second harmonic generation through multi-layer medium SiO2/liquid specimen/SiO2. Frequency dependence of the nonlinear characterization curve for water in 110-155 MHz is numerically and experimentally investigated. With the measured dip position and the new model, values of B/A for water are evaluated. The results show that the present method can effectively correct the diffraction effect in the measurement.

[Dependence of anti-inflammatory effects of high peak-power pulsed electromagnetic radiation of extremely high frequency on exposure parameters].

PubMed

Gapeev, A B; Mikhaĭlik, E N; Rubanik, A V; Cheremis, N K

2007-01-01

A pronounced anti-inflammatory effect of high peak-power pulsed electromagnetic radiation of extremely high frequency was shown for the first time in a model of zymosan-induced footpad edema in mice. Exposure to radiation of specific parameters (35, 27 GHz, peak power 20 kW, pulse widths 400-600 ns, pulse repetition frequency 5-500 Hz) decreased the exudative edema and local hyperthermia by 20% compared to the control. The kinetics and the magnitude of the anti-inflammatory effect were comparable with those induced by sodium diclofenac at a dose of 3 mg/kg. It was found that the anti-inflammatory effect linearly increased with increasing pulse width at a fixed pulse repetition frequency and had threshold dependence on the average incident power density of the radiation at a fixed pulse width. When animals were whole-body exposed in the far-field zone of radiator, the optimal exposure duration was 20 min. Increasing the average incident power density upon local exposure of the inflamed paw accelerated both the development of the anti-inflammatory effect and the reactivation time. The results obtained will undoubtedly be of great importance in the hygienic standardization of pulsed electromagnetic radiation and in further studies of the mechanisms of its biological action.

High frequency testing of rubber mounts.

PubMed

Vahdati, Nader; Saunders, L Ken Lauderbaugh

2002-04-01

Rubber and fluid-filled rubber engine mounts are commonly used in automotive and aerospace applications to provide reduced cabin noise and vibration, and/or motion accommodations. In certain applications, the rubber mount may operate at frequencies as high as 5000 Hz. Therefore, dynamic stiffness of the mount needs to be known in this frequency range. Commercial high frequency test machines are practically nonexistent, and the best high frequency test machine on the market is only capable of frequencies as high as 1000 Hz. In this paper, a high frequency test machine is described that allows test engineers to study the high frequency performance of rubber mounts at frequencies up to 5000 Hz.

An inkjet vision measurement technique for high-frequency jetting

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kwon, Kye-Si, E-mail: kskwon@sch.ac.kr; Jang, Min-Hyuck; Park, Ha Yeong

2014-06-15

Inkjet technology has been used as manufacturing a tool for printed electronics. To increase the productivity, the jetting frequency needs to be increased. When using high-frequency jetting, the printed pattern quality could be non-uniform since the jetting performance characteristics including the jetting speed and droplet volume could vary significantly with increases in jet frequency. Therefore, high-frequency jetting behavior must be evaluated properly for improvement. However, it is difficult to measure high-frequency jetting behavior using previous vision analysis methods, because subsequent droplets are close or even merged. In this paper, we present vision measurement techniques to evaluate the drop formation ofmore » high-frequency jetting. The proposed method is based on tracking target droplets such that subsequent droplets can be excluded in the image analysis by focusing on the target droplet. Finally, a frequency sweeping method for jetting speed and droplet volume is presented to understand the overall jetting frequency effects on jetting performance.« less

Evaluation of UTLS Carbon Monoxide Simulations in GMI and GEOS-Chem Chemical Transport Models using Aura MLS Observations

NASA Technical Reports Server (NTRS)

Huang, Lei; Jiang, Jonathan H.; Murray, Lee T.; Damon, Megan R.; Su, Hui; Livesey, Nathaniel J.

2016-01-01

This study evaluates the distribution and variation of carbon monoxide (CO) in the upper troposphere and lower stratosphere (UTLS) during 2004-2012 as simulated by two chemical transport models, using the latest version of Aura Microwave Limb Sounder (MLS) observations. The simulated spatial distributions, temporal variations and vertical transport of CO in the UTLS region are compared with those observed by MLS. We also investigate the impact of surface emissions and deep convection on CO concentrations in the UTLS over different regions, using both model simulations and MLS observations. Global Modeling Initiative (GMI) and GEOS-Chem simulations of UTLS CO both show similar spatial distributions to observations. The global mean CO values simulated by both models agree with MLS observations at 215 and 147 hPa, but are significantly underestimated by more than 40% at 100 hPa. In addition, the models underestimate the peak CO values by up to 70% at 100 hPa, 60% at 147 hPa and 40% at 215 hPa, with GEOS-Chem generally simulating more CO at 100 hPa and less CO at 215 hPa than GMI. The seasonal distributions of CO simulated by both models are in better agreement with MLS in the Southern Hemisphere (SH) than in the Northern Hemisphere (NH), with disagreements between model and observations over enhanced CO regions such as southern Africa. The simulated vertical transport of CO shows better agreement with MLS in the tropics and the SH subtropics than the NH subtropics. We also examine regional variations in the relationships among surface CO emission, convection and UTLS CO concentrations. The two models exhibit emission-convection- CO relationships similar to those observed by MLS over the tropics and some regions with enhanced UTLS CO.

Extremely high frequency electromagnetic irradiation in combination with antibiotics enhances antibacterial effects on Escherichia coli.

PubMed

Torgomyan, Heghine; Tadevosyan, Hasmik; Trchounian, Armen

2011-03-01

Antibacterial effects of the electromagnetic irradiation (EMI) of 51.8 and 53 GHz frequencies with low intensity (the flux capacity of 0.06 mW/cm(2)) and non-thermal action were investigated upon direct irradiation of E. coli K12. Significant decrease in bacterial growth rate and in the number of viable cells, marked change in H(+) and K(+) transport across membrane were shown. Subsequent addition of kanamycin or ceftriaxone (15 or 0.4 μM, respectively) enhanced the effects of irradiation. This was maximally achieved at the frequency of 53 GHz. These all might reveal membrane as probable target for antibacterial effects. Apparently, the action of EMI on bacteria might lead to changed membrane properties and to antibiotic resistance. The results should improve using extremely high frequency EMI in combination with antibiotics in biotechnology, therapeutic practice, and food industry.

Trace Gas/Aerosol Interactions and GMI Modeling Support

NASA Technical Reports Server (NTRS)

Penner, Joyce E.; Liu, Xiaohong; Das, Bigyani; Bergmann, Dan; Rodriquez, Jose M.; Strahan, Susan; Wang, Minghuai; Feng, Yan

2005-01-01

Current global aerosol models use different physical and chemical schemes and parameters, different meteorological fields, and often different emission sources. Since the physical and chemical parameterization schemes are often tuned to obtain results that are consistent with observations, it is difficult to assess the true uncertainty due to meteorology alone. Under the framework of the NASA global modeling initiative (GMI), the differences and uncertainties in aerosol simulations (for sulfate, organic carbon, black carbon, dust and sea salt) solely due to different meteorological fields are analyzed and quantified. Three meteorological datasets available from the NASA DAO GCM, the GISS-II' GCM, and the NASA finite volume GCM (FVGCM) are used to drive the same aerosol model. The global sulfate and mineral dust burdens with FVGCM fields are 40% and 20% less than those with DAO and GISS fields, respectively due to its heavier rainfall. Meanwhile, the sea salt burden predicted with FVGCM fields is 56% and 43% higher than those with DAO and GISS, respectively, due to its stronger convection especially over the Southern Hemispheric Ocean. Sulfate concentrations at the surface in the Northern Hemisphere extratropics and in the middle to upper troposphere differ by more than a factor of 3 between the three meteorological datasets. The agreement between model calculated and observed aerosol concentrations in the industrial regions (e.g., North America and Europe) is quite similar for all three meteorological datasets. Away from the source regions, however, the comparisons with observations differ greatly for DAO, FVGCM and GISS, and the performance of the model using different datasets varies largely depending on sites and species. Global annual average aerosol optical depth at 550 nm is 0.120-0.131 for the three meteorological datasets.

Evaluation of GMI and PMI diffeomorphic‐based demons algorithms for aligning PET and CT Images

PubMed Central

Yang, Juan; Zhang, You; Yin, Yong

2015-01-01

Fusion of anatomic information in computed tomography (CT) and functional information in F18‐FDG positron emission tomography (PET) is crucial for accurate differentiation of tumor from benign masses, designing radiotherapy treatment plan and staging of cancer. Although current PET and CT images can be acquired from combined F18‐FDG PET/CT scanner, the two acquisitions are scanned separately and take a long time, which may induce potential positional errors in global and local caused by respiratory motion or organ peristalsis. So registration (alignment) of whole‐body PET and CT images is a prerequisite for their meaningful fusion. The purpose of this study was to assess the performance of two multimodal registration algorithms for aligning PET and CT images. The proposed gradient of mutual information (GMI)‐based demons algorithm, which incorporated the GMI between two images as an external force to facilitate the alignment, was compared with the point‐wise mutual information (PMI) diffeomorphic‐based demons algorithm whose external force was modified by replacing the image intensity difference in diffeomorphic demons algorithm with the PMI to make it appropriate for multimodal image registration. Eight patients with esophageal cancer(s) were enrolled in this IRB‐approved study. Whole‐body PET and CT images were acquired from a combined F18‐FDG PET/CT scanner for each patient. The modified Hausdorff distance (dMH) was used to evaluate the registration accuracy of the two algorithms. Of all patients, the mean values and standard deviations (SDs) of dMH were 6.65 (± 1.90) voxels and 6.01 (± 1.90) after the GMI‐based demons and the PMI diffeomorphic‐based demons registration algorithms respectively. Preliminary results on oncological patients showed that the respiratory motion and organ peristalsis in PET/CT esophageal images could not be neglected, although a combined F18‐FDG PET/CT scanner was used for image acquisition. The PMI

Characterization of High-Frequency Excitation of a Wake by Simulation

NASA Technical Reports Server (NTRS)

Cain, Alan B.; Rogers, Michael M.; Kibens, Valdis; Mansour, Nagi (Technical Monitor)

2003-01-01

Insights into the effects of high-frequency forcing on free shear layer evolution are gained through analysis of several direct numerical simulations. High-frequency forcing of a fully turbulent plane wake results in only a weak transient effect. On the other hand, significant changes in the developed turbulent state may result when high-frequency forcing is applied to a transitional wake. The impacts of varying the characteristics of the high-frequency forcing are examined, particularly, the streamwise wavenumber band in which forcing is applied and the initial amplitude of the forcing. The high-frequency excitation is found to increase the dissipation rate of turbulent kinetic energy, to reduce the turbulent kinetic energy production rate, and to reduce the turbulent kinetic energy suppression increases with forcing amplitude once a threshold level has been reached. For a given initial forcing energy, the largest reduction in turbulent kinetic energy density was achieved by forcing wavenumbers that are about two to three times the neutral wavenumber determined from linear stability theory.

Carbon nanotube transistor based high-frequency electronics

NASA Astrophysics Data System (ADS)

Schroter, Michael

At the nanoscale carbon nanotubes (CNTs) have higher carrier mobility and carrier velocity than most incumbent semiconductors. Thus CNT based field-effect transistors (FETs) are being considered as strong candidates for replacing existing MOSFETs in digital applications. In addition, the predicted high intrinsic transit frequency and the more recent finding of ways to achieve highly linear transfer characteristics have inspired investigations on analog high-frequency (HF) applications. High linearity is extremely valuable for an energy efficient usage of the frequency spectrum, particularly in mobile communications. Compared to digital applications, the much more relaxed constraints for CNT placement and lithography combined with already achieved operating frequencies of at least 10 GHz for fabricated devices make an early entry in the low GHz HF market more feasible than in large-scale digital circuits. Such a market entry would be extremely beneficial for funding the development of production CNTFET based process technology. This talk will provide an overview on the present status and feasibility of HF CNTFET technology will be given from an engineering point of view, including device modeling, experimental results, and existing roadblocks.

A probable aculeacin A acylase from the Ralstonia solanacearum GMI1000 is N-acyl-homoserine lactone acylase with quorum-quenching activity

PubMed Central

2009-01-01

Background The infection and virulence functions of diverse plant and animal pathogens that possess quorum sensing systems are regulated by N-acylhomoserine lactones (AHLs) acting as signal molecules. AHL-acylase is a quorum quenching enzyme and degrades AHLs by removing the fatty acid side chain from the homoserine lactone ring of AHLs. This blocks AHL accumulation and pathogenic phenotypes in quorum sensing bacteria. Results An aac gene of undemonstrated function from Ralstonia solanacearum GMI1000 was cloned, expressed in Escherichia coli; it inactivated four AHLs that were tested. The sequence of the 795 amino acid polypeptide was considerably similar to the AHL-acylase from Ralstonia sp. XJ12B with 83% identity match and shared 39% identity with an aculeacin A acylase precursor from the gram-positive actinomycete Actinoplanes utahensis. Aculeacin A is a neutral lipopeptide antibiotic and an antifungal drug. An electrospray ionisation mass spectrometry (ESI-MS) analysis verified that Aac hydrolysed the amide bond of AHL, releasing homoserine lactone and the corresponding fatty acids. However, ESI-MS analysis demonstrated that the Aac could not catalyze the hydrolysis of the palmitoyl moiety of the aculeacin A. Moreover, the results of MIC test of aculeacin A suggest that Aac could not deacylate aculeacin A. The specificity of Aac for AHLs showed a greater preference for long acyl chains than for short acyl chains. Heterologous expression of the aac gene in Chromobacterium violaceum CV026 effectively inhibited violacein and chitinase activity, both of which were regulated by the quorum-sensing mechanism. These results indicated that Aac could control AHL-dependent pathogenicity. Conclusion This is the first study to find an AHL-acylase in a phytopathogen. Our data provide direct evidence that the functioning of the aac gene (NP520668) of R. solanacearum GMI1000 is via AHL-acylase and not via aculeacin A acylase. Since Aac is a therapeutic potential quorum

Low- and high-frequency transcutaneous electrical nerve stimulation have no deleterious or teratogenic effects on pregnant mice.

PubMed

Yokoyama, L M; Pires, L A; Ferreira, E A Gonçalves; Casarotto, R A

2015-06-01

To evaluate the effects of application of transcutaneous electrical nerve stimulation (TENS) at low and high frequencies to the abdomens of Swiss mice throughout pregnancy. Experimental animal study. Research laboratory. Thirty Swiss mice received TENS throughout pregnancy. They were divided into three groups (n=10): placebo, low-frequency TENS (LF group) and high-frequency TENS (HF group). In the placebo group, the electrodes were applied to the abdominal region without any electrical current. In the LF group, the frequency was 10 Hz, pulse duration was 200 μs and intensity started at 2 mA. In the HF group, the same parameters were applied and the frequency was 150 Hz. All stimulation protocols were applied for 20 min/day from Day 0 until Day 20. The pregnant mice were weighed on Days 0, 7, 14 and 20 to verify weekly weight gain by two-way analysis of variance. The numbers of fetuses, placentas, implantations, resorptions and major external fetal malformations on Day 20 were analysed using the Kruskal-Wallis test. No significant differences were found between the placebo and TENS groups (P>0.05). Application of low- and high-frequency TENS to the abdomens of pregnant mice did not cause any deleterious or major teratogenic effects. Copyright © 2014 Chartered Society of Physiotherapy. Published by Elsevier Ltd. All rights reserved.

Research for the jamming mechanism of high-frequency laser to the laser seeker

NASA Astrophysics Data System (ADS)

Zheng, Xingyuan; Zhang, Haiyang; Wang, Yunping; Feng, Shuang; Zhao, Changming

2013-08-01

High-frequency laser will be able to enter the enemy laser signal processing systems without encoded identification and a copy. That makes it one of the research directions of new interference sources. In order to study the interference mechanism of high-frequency laser to laser guided weapons. According to the principle of high-frequency laser interference, a series of related theoretical models such as a semi-active laser seeker coded identification model, a time door model, multi-signal processing model and a interference signal modulation processing model are established. Then seeker interfere with effective 3σ criterion is proposed. Based on this, the study of the effect of multi-source interference and signal characteristics of the effect of high repetition frequency laser interference are key research. According to the simulation system testing, the results show that the multi-source interference and interference signal frequency modulation can effectively enhance the interference effect. While the interference effect of the interference signal amplitude modulation is not obvious. The research results will provide the evaluation of high-frequency laser interference effect and provide theoretical references for high-frequency laser interference system application.

High frequency transcutaneous electrical nerve stimulation with diphenidol administration results in an additive antiallodynic effect in rats following chronic constriction injury.

PubMed

Lin, Heng-Teng; Chiu, Chong-Chi; Wang, Jhi-Joung; Hung, Ching-Hsia; Chen, Yu-Wen

2015-03-04

The impact of coadministration of transcutaneous electrical nerve stimulation (TENS) and diphenidol is not well established. Here we estimated the effects of diphenidol in combination with TENS on mechanical allodynia and tumor necrosis factor-α (TNF-α) expression. Using an animal chronic constriction injury (CCI) model, the rat was estimated for evidence of mechanical sensitivity via von Frey hair stimulation and TNF-α expression in the sciatic nerve using the ELISA assay. High frequency (100Hz) TENS or intraperitoneal injection of diphenidol (2.0μmol/kg) was applied daily, starting on postoperative day 1 (POD1) and lasting for the next 13 days. We demonstrated that both high frequency TENS and diphenidol groups had an increase in mechanical withdrawal thresholds of 60%. Coadministration of high frequency TENS and diphenidol gives better results of paw withdrawal thresholds in comparison with high frequency TENS alone or diphenidol alone. Both diphenidol and coadministration of high frequency TENS with diphenidol groups showed a significant reduction of the TNF-α level compared with the CCI or HFS group (P<0.05) in the sciatic nerve on POD7, whereas the CCI or high frequency TENS group exhibited a higher TNF-α level than the sham group (P<0.05). Our resulting data revealed that diphenidol alone, high frequency TENS alone, and the combination produced a reduction of neuropathic allodynia. Both diphenidol and the combination of diphenidol with high frequency TENS inhibited TNF-α expression. A moderately effective dose of diphenidol appeared to have an additive effect with high frequency TENS. Therefore, multidisciplinary treatments could be considered for this kind of mechanical allodynia. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

High frequency-heated air turbojet

NASA Technical Reports Server (NTRS)

Miron, J. H. D.

1986-01-01

A description is given of a method to heat air coming from a turbojet compressor to a temperature necessary to produce required expansion without requiring fuel. This is done by high frequency heating, which heats the walls corresponding to the combustion chamber in existing jets, by mounting high frequency coils in them. The current transformer and high frequency generator to be used are discussed.

Experimental observation of standing wave effect in low-pressure very-high-frequency capacitive discharges

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Yong-Xin; Gao, Fei; Liu, Jia

2014-07-28

Radial uniformity measurements of plasma density were carried out by using a floating double probe in a cylindrical (21 cm in electrode diameter) capacitive discharge reactor driven over a wide range of frequencies (27–220 MHz). At low rf power, a multiple-node structure of standing wave effect was observed at 130 MHz. The secondary density peak caused by the standing wave effect became pronounced and shifts toward the axis as the driving frequency further to increase, indicative of a much more shortened standing-wave wavelength. With increasing rf power, the secondary density peak shift toward the radial edge, namely, the standing-wave wavelength was increased,more » in good qualitative agreement with the previous theory and simulation results. At higher pressures and high frequencies, the rf power was primarily deposited at the periphery of the electrode, due to the fact that the waves were strongly damped as they propagated from the discharge edge into the center.« less

Effects of Osteopathic Manipulative Therapy on Pain and Mood Disorders in Patients With High-Frequency Migraine.

PubMed

D'Ippolito, Mariagrazia; Tramontano, Marco; Buzzi, Maria Gabriella

2017-06-01

The substantial functional impairment associated with migraine has both physical and emotional ramifications. Mood disorders are often comorbid in patients with migraine and are known to adversely affect migraine activity. To explore the effects of osteopathic manipulative therapy (OMTh; manipulative care provided by foreign-trained osteopaths) on pain and mood disorders in patients with high-frequency migraine. Retrospective review of the medical records of patients with high-frequency migraine who were treated with OMTh at the Headache Istituto di Ricovero e Cura a Carattere Scientifico Fondazione Santa Lucia from 2011 to 2015. Clinical assessments were made using the Headache Disability Inventory (HDI), the Headache Impact Test (HIT-6), the Hamilton Depression Rating Scale (HDRS), and the State-Trait Anxiety Inventory (STAI) forms X-1 and X-2. Medical records of 11 patients (6 women; mean age, 47.5 [7.8] years) with a diagnosis of high-frequency migraine who participated in an OMTh program met the inclusion criteria and were included in the study. When the questionnaire scores obtained at the first visit (T0) and after 4 OMTh sessions (T1) were compared, significant improvement in scores were observed on STAI X-2 (T0: 43.18 [2.47]; T1: 39.45 [2.52]; P<.05), HIT-6 (T0: 63 [2.20]; T1: 56.27 [2.24]; P<.05), and HDI (T0: 58.72 [6.75]; T1: 45.09 [7.01]; P<.05). This preliminary study revealed that patients with high-frequency migraine and comorbid mood disorders showed significant improvement after four 45-minute OMTh sessions. Further investigation into the effects of OMTh on pain and mood disorders in patients with high-frequency migraine is needed.

The Effects of Filter Cutoff Frequency on Musculoskeletal Simulations of High-Impact Movements.

PubMed

Tomescu, Sebastian; Bakker, Ryan; Beach, Tyson A C; Chandrashekar, Naveen

2018-02-12

Estimation of muscle forces through musculoskeletal simulation is important in understanding human movement and injury. Unmatched filter frequencies used to low-pass filter marker and force platform data can create artifacts during inverse dynamics analysis, but their effects on muscle force calculations are unknown. The objective of this study was to determine the effects of filter cutoff frequency on simulation parameters and magnitudes of lower extremity muscle and resultant joint contact forces during a high-impact maneuver. Eight participants performed a single leg jump-landing. Kinematics were captured with a 3D motion capture system and ground reaction forces were recorded with a force platform. The marker and force platform data were filtered using two matched filter frequencies (10-10Hz, 15-15Hz) and two unmatched frequencies (10-50Hz, 15-50Hz). Musculoskeletal simulations using Computed Muscle Control were performed in OpenSim. The results revealed significantly higher peak quadriceps (13%), hamstrings (48%), and gastrocnemius forces (69%) in the unmatched (10-50Hz, 15-50Hz) conditions than in the matched (10-10Hz, 15-15Hz) conditions (p<0.05). Resultant joint contact forces and reserve (non-physiologic) moments were similarly larger in the unmatched filter categories (p<0.05). This study demonstrated that artifacts created from filtering with unmatched filter cutoffs result in altered muscle forces and dynamics which are not physiologic.

Parametric Study of High Frequency Pulse Detonation Tubes

NASA Technical Reports Server (NTRS)

Cutler, Anderw D.

2008-01-01

This paper describes development of high frequency pulse detonation tubes similar to a small pulse detonation engine (PDE). A high-speed valve injects a charge of a mixture of fuel and air at rates of up to 1000 Hz into a constant area tube closed at one end. The reactants detonate in the tube and the products exit as a pulsed jet. High frequency pressure transducers are used to monitor the pressure fluctuations in the device and thrust is measured with a balance. The effects of injection frequency, fuel and air flow rates, tube length, and injection location are considered. Both H2 and C2H4 fuels are considered. Optimum (maximum specific thrust) fuel-air compositions and resonant frequencies are identified. Results are compared to PDE calculations. Design rules are postulated and applications to aerodynamic flow control and propulsion are discussed.

Frequency Compounded Imaging with a High-Frequency Dual Element Transducer

PubMed Central

Chang, Jin Ho; Kim, Hyung Ham; Lee, Jungwoo; Shung, K. Kirk

2014-01-01

This paper proposes a frequency compounding method to reduce speckle interferences, where a concentric annular type high-frequency dual element transducer is used to broaden the bandwidth of an imaging system. In frequency compounding methods, frequency division is carried out to obtain sub-band images containing uncorrelated speckles, which sacrifices axial resolution. Therefore, frequency compounding often deteriorates the target-detecting capability, quantified by the total signal-to-noise ratio (SNR), when the speckle’s SNR (SSNR) is not improved as much as the degraded axial resolution. However, this could be avoided if the effective bandwidth required for frequency compounding is increased. The primary goal of the proposed approach, hence, is to improve SSNR by a factor of two under the condition where axial resolution is degraded by a factor of less than two, which indicates the total SNR improvement to higher than 40% compared to that of an original image. Since the method here employs a dual element transducer operating at 20 and 40 MHz, the effective bandwidth necessary for frequency compounding becomes broadened. By dividing each spectrum of RF samples from both elements into two sub-bands, this method eventually enables four sets of the sub-band samples to contain uncorrelated speckles. This causes the axial resolution to be reduced by a factor of as low as 1.85, which means that this method would improve total SNR by at least 47 %. An in vitro experiment on an excised pig eye was performed to validate the proposed approach, and the results showed that the SSNR was improved from 2.081±0.365 in the original image to 4.206±0.635 in the final compounding image. PMID:19914674

Frequency compounded imaging with a high-frequency dual element transducer.

PubMed

Chang, Jin Ho; Kim, Hyung Ham; Lee, Jungwoo; Shung, K Kirk

2010-04-01

This paper proposes a frequency compounding method to reduce speckle interferences, where a concentric annular type high-frequency dual element transducer is used to broaden the bandwidth of an imaging system. In frequency compounding methods, frequency division is carried out to obtain sub-band images containing uncorrelated speckles, which sacrifices axial resolution. Therefore, frequency compounding often deteriorates the target-detecting capability, quantified by the total signal-to-noise ratio (SNR), when the speckle's SNR (SSNR) is not improved as much as the degraded axial resolution. However, this could be avoided if the effective bandwidth required for frequency compounding is increased. The primary goal of the proposed approach, hence, is to improve SSNR by a factor of two under the condition where axial resolution is degraded by a factor of less than two, which indicates the total SNR improvement to higher than 40% compared to that of an original image. Since the method here employs a dual element transducer operating at 20 and 40MHz, the effective bandwidth necessary for frequency compounding becomes broadened. By dividing each spectrum of RF samples from both elements into two sub-bands, this method eventually enables four sets of the sub-band samples to contain uncorrelated speckles. This causes the axial resolution to be reduced by a factor of as low as 1.85, which means that this method would improve total SNR by at least 47%. An in vitro experiment on an excised pig eye was performed to validate the proposed approach, and the results showed that the SSNR was improved from 2.081+/-0.365 in the original image to 4.206+/-0.635 in the final compounding image. Copyright 2009 Elsevier B.V. All rights reserved.

Modulation of high frequency noise by engine tones of small boats.

PubMed

Pollara, Alexander; Sutin, Alexander; Salloum, Hady

2017-07-01

The effect of modulation of high frequency ship noise by propeller rotation frequencies is well known. This modulation is observed with the Detection of Envelope Modulation on Noise (DEMON) algorithm. Analysis of the DEMON spectrum allows the revolutions per minute and number of blades of the propeller to be determined. This work shows that the high frequency noise of a small boat can also be modulated by engine frequencies. Prior studies have not reported high frequency noise amplitude modulated at engine frequencies. This modulation is likely produced by bubbles from the engine exhaust system.

High frequency copolymer ultrasonic transducer array of size-effective elements

NASA Astrophysics Data System (ADS)

Decharat, Adit; Wagle, Sanat; Habib, Anowarul; Jacobsen, Svein; Melandsø, Frank

2018-02-01

A layer-by-layer deposition method for producing dual-layer ultrasonic transducers from piezoelectric copolymers has been developed. The method uses a combination of customized and standard processing to obtain 2D array transducers with electrical connection of the individual elements routed directly to the rear of the substrate. A numerical model was implemented to study basic parameters effecting the transducer characteristics. Key elements of the array were characterized and evaluated, demonstrating its viability of 2D imaging. Signal reproducibility of the prototype array was studied by characterizing the variations of the center frequency (≈42 MHz) and bandwidth (≈25 MHz) of the acoustic. Object identification was also tested and parameterized by acoustic-field beamwidth as well as proper scan step size. Simple tests to illustrate a benefit of multi-element scan on lowering the inspection time were conducted. Structural imaging of the test structure underneath multi-layered wave media (glass plate and distilled water) was also performed. The prototype presented in this work is an important step towards realizing an inexpensive, compact array of individually operated copolymer transducers that can serve in a fast/volumetric high frequency (HF) ultrasonic scanning platform.

Interplay between morphology and frequency in lexical access: The case of the base frequency effect

PubMed Central

Vannest, Jennifer; Newport, Elissa L.; Newman, Aaron J.; Bavelier, Daphne

2011-01-01

A major issue in lexical processing concerns storage and access of lexical items. Here we make use of the base frequency effect to examine this. Specifically, reaction time to morphologically complex words (words made up of base and suffix, e.g., agree+able) typically reflects frequency of the base element (i.e., total frequency of all words in which agree appears) rather than surface word frequency (i.e., frequency of agreeable itself). We term these complex words decomposable. However, a class of words termed whole-word do not show such sensitivity to base frequency (e.g., serenity). Using an event-related MRI design, we exploited the fact that processing low-frequency words increases BOLD activity relative to high frequency ones, and examined effects of base frequency on brain activity for decomposable and whole-word items. Morphologically complex words, half high and half low base frequency, were compared to matched high and low frequency simple monomorphemic words using a lexical decision task. Morphologically complex words increased activation in left inferior frontal and left superior temporal cortices versus simple words. The only area to mirror the behavioral distinction between decomposable and whole-word types was the thalamus. Surprisingly, most frequency-sensitive areas failed to show base frequency effects. This variety of responses to frequency and word type across brain areas supports an integrative view of multiple variables during lexical access, rather than a dichotomy between memory-based access and on-line computation. Lexical access appears best captured as interplay of several neural processes with different sensitivities to various linguistic factors including frequency and morphological complexity. PMID:21167136

Photonic Generation of High Power, Ultrastable Microwave Signals by Vernier Effect in a Femtosecond Laser Frequency Comb.

PubMed

Saleh, Khaldoun; Millo, Jacques; Marechal, Baptiste; Dubois, Benoît; Bakir, Ahmed; Didier, Alexandre; Lacroûte, Clément; Kersalé, Yann

2018-01-31

Optical frequency division of an ultrastable laser to the microwave frequency range by an optical frequency comb has allowed the generation of microwave signals with unprecedently high spectral purity and stability. However, the generated microwave signal will suffer from a very low power level if no external optical frequency comb repetition rate multiplication device is used. This paper reports theoretical and experimental studies on the beneficial use of the Vernier effect together with the spectral selective filtering in a double directional coupler add-drop optical fibre ring resonator to increase the comb repetition rate and generate high power microwaves. The studies are focused on two selective filtering aspects: the high rejection of undesirable optical modes of the frequency comb and the transmission of the desirable modes with the lowest possible loss. Moreover, the conservation of the frequency comb stability and linewidth at the resonator output is particularly considered. Accordingly, a fibre ring resonator is designed, fabricated, and characterized, and a technique to stabilize the resonator's resonance comb is proposed. A significant power gain is achieved for the photonically generated beat note at 10 GHz. Routes to highly improve the performances of such proof-of-concept device are also discussed.

Dependence of cavitation, chemical effect, and mechanical effect thresholds on ultrasonic frequency.

PubMed

Thanh Nguyen, Tam; Asakura, Yoshiyuki; Koda, Shinobu; Yasuda, Keiji

2017-11-01

Cavitation, chemical effect, and mechanical effect thresholds were investigated in wide frequency ranges from 22 to 4880kHz. Each threshold was measured in terms of sound pressure at fundamental frequency. Broadband noise emitted from acoustic cavitation bubbles was detected by a hydrophone to determine the cavitation threshold. Potassium iodide oxidation caused by acoustic cavitation was used to quantify the chemical effect threshold. The ultrasonic erosion of aluminum foil was conducted to estimate the mechanical effect threshold. The cavitation, chemical effect, and mechanical effect thresholds increased with increasing frequency. The chemical effect threshold was close to the cavitation threshold for all frequencies. At low frequency below 98kHz, the mechanical effect threshold was nearly equal to the cavitation threshold. However, the mechanical effect threshold was greatly higher than the cavitation threshold at high frequency. In addition, the thresholds of the second harmonic and the first ultraharmonic signals were measured to detect bubble occurrence. The threshold of the second harmonic approximated to the cavitation threshold below 1000kHz. On the other hand, the threshold of the first ultraharmonic was higher than the cavitation threshold below 98kHz and near to the cavitation threshold at high frequency. Copyright © 2017 Elsevier B.V. All rights reserved.

Design and calibration of a high-frequency oscillatory ventilator.

PubMed

Simon, B A; Mitzner, W

1991-02-01

High-frequency ventilation (HFV) is a modality of mechanical ventilation which presents difficult technical demands to the clinical or laboratory investigator. The essential features of an ideal HFV system are described, including wide frequency range, control of tidal volume and mean airway pressure, minimal dead space, and high effective internal impedance. The design and performance of a high-frequency oscillatory ventilation system is described which approaches these requirements. The ventilator utilizes a linear motor regulated by a closed loop controller and driving a novel frictionless double-diaphragm piston pump. Finally, the ventilator performance is tested using the impedance model of Venegas [1].

Design of matching layers for high-frequency ultrasonic transducers

PubMed Central

Fei, Chunlong; Ma, Jianguo; Chiu, Chi Tat; Williams, Jay A.; Fong, Wayne; Chen, Zeyu; Zhu, BenPeng; Xiong, Rui; Shi, Jing; Hsiai, Tzung K.; Shung, K. Kirk; Zhou, Qifa

2015-01-01

Matching the acoustic impedance of high-frequency (≥100 MHz) ultrasound transducers to an aqueous loading medium remains a challenge for fabricating high-frequency transducers. The traditional matching layer design has been problematic to establish high matching performance given requirements on both specific acoustic impedance and precise thickness. Based on both mass-spring scheme and microwave matching network analysis, we interfaced metal-polymer layers for the matching effects. Both methods hold promises for guiding the metal-polymer matching layer design. A 100 MHz LiNbO3 transducer was fabricated to validate the performance of the both matching layer designs. In the pulse-echo experiment, the transducer echo amplitude increased by 84.4% and its −6dB bandwidth increased from 30.2% to 58.3% comparing to the non-matched condition, demonstrating that the matching layer design method is effective for developing high-frequency ultrasonic transducers. PMID:26445518

Centrifugal compressor modifications and their effect on high-frequency pipe wall vibration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Motriuk, R.W.; Harvey, D.P.

1998-08-01

High-frequency pulsation generated by centrifugal compressors, with pressure wave-lengths much smaller than the attached pipe diameter, can cause fatigue failures of the compressor internals, impair compressor performance, and damage the attached compressor piping. There are numerous sources producing pulsation in centrifugal compressors. Some of them are discussed in literature at large (Japikse, 1995; Niese, 1976). NGTL has experienced extreme high-frequency discharge pulsation and pipe wall vibration on many of its radial inlet high-flow centrifugal gas compressor facilities. These pulsations led to several piping attachment failures and compressor internal component failures while the compressor operated within the design envelope. This papermore » considers several pulsation conditions at an NGTL compression facility which resulted in unacceptable piping vibration. Significant vibration attenuation was achieved by modifying the compressor (pulsation source) through removal of the diffuser vanes and partial removal of the inlet guide vanes (IGV). Direct comparison of the changes in vibration, pulsation, and performance are made for each of the modifications. The vibration problem, probable causes, options available to address the problem, and the results of implementation are reviewed. The effects of diffuser vane removal on discharge pipe wall vibration as well as changes in compressor performance are described.« less

Effects of bandwidth, compression speed, and gain at high frequencies on preferences for amplified music.

PubMed

Moore, Brian C J

2012-09-01

This article reviews a series of studies on the factors influencing sound quality preferences, mostly for jazz and classical music stimuli. The data were obtained using ratings of individual stimuli or using the method of paired comparisons. For normal-hearing participants, the highest ratings of sound quality were obtained when the reproduction bandwidth was wide (55 to 16000 Hz) and ripples in the frequency response were small (less than ± 5 dB). For hearing-impaired participants listening via a simulated five-channel compression hearing aid with gains set using the CAM2 fitting method, preferences for upper cutoff frequency varied across participants: Some preferred a 7.5- or 10-kHz upper cutoff frequency over a 5-kHz cutoff frequency, and some showed the opposite preference. Preferences for a higher upper cutoff frequency were associated with a shallow high-frequency slope of the audiogram. A subsequent study comparing the CAM2 and NAL-NL2 fitting methods, with gains slightly reduced for participants who were not experienced hearing aid users, showed a consistent preference for CAM2. Since the two methods differ mainly in the gain applied for frequencies above 4 kHz (CAM2 recommending higher gain than NAL-NL2), these results suggest that extending the upper cutoff frequency is beneficial. A system for reducing "overshoot" effects produced by compression gave small but significant benefits for sound quality of a percussion instrument (xylophone). For a high-input level (80 dB SPL), slow compression was preferred over fast compression.

Effects of excitation frequency on high-order terahertz sideband generation in semiconductors

NASA Astrophysics Data System (ADS)

Xie, Xiao-Tao; Zhu, Bang-Fen; Liu, Ren-Bao

2013-10-01

We theoretically investigate the effects of the excitation frequency on the plateau of high-order terahertz sideband generation (HSG) in semiconductors driven by intense terahertz (THz) fields. We find that the plateau of the sideband spectrum strongly depends on the detuning between the near-infrared laser field and the band gap. We use the quantum trajectory theory (three-step model) to understand the HSG. In the three-step model, an electron-hole pair is first excited by a weak laser, then driven by the strong THz field, and finally recombined to emit a photon with energy gain. When the laser is tuned below the band gap (negative detuning), the electron-hole generation is a virtual process that requires quantum tunneling to occur. When the energy gained by the electron-hole pair from the THz field is less than 3.17 times the ponderomotive energy (Up), the electron and the hole can be driven to the same position and recombined without quantum tunneling, so that the HSG will have large probability amplitude. This leads to a plateau feature of the HSG spectrum with a high-frequency cutoff at about 3.17Up above the band gap. Such a plateau feature is similar to the case of high-order harmonics generation in atoms where electrons have to overcome the binding energy to escape the atomic core. A particularly interesting excitation condition in HSG is that the laser can be tuned above the band gap (positive detuning), corresponding to the unphysical ‘negative’ binding energy in atoms for high-order harmonic generation. Now the electron-hole pair is generated by real excitation, but the recombination process can be real or virtual depending on the energy gained from the THz field, which determines the plateau feature in HSG. Both the numerical calculation and the quantum trajectory analysis reveal that for positive detuning, the HSG plateau cutoff depends on the frequency of the excitation laser. In particular, when the laser is tuned more than 3.17Up above the band

Effects of high fire frequency in creosote bush scrub vegetation of the Mojave Desert

USGS Publications Warehouse

Brooks, M.L.

2012-01-01

Plant invasions can increase fire frequency in desert ecosystems where fires were historically infrequent. Although there are many resource management concerns associated with high frequency fire in deserts, fundamental effects on plant community characteristics remain largely unstudied. Here I describe the effects of fire frequency on creosote bush scrub vegetation in the Mojave Desert, USA. Biomass of the invasive annual grass Bromus rubens L. increased following fire, but did not increase further with additional fires. In contrast, density, cover and species richness of native perennial plants each decreased following fire and continued to decrease with subsequent fires, although not as dramatically as after the initial fire. Responses were similar 5 and 14 years post-fire, except that cover of Hymenoclea salsola Torr. & A. Gray and Achnatherum speciosa Trin. & Rupr. both increased in areas burnt once. These results suggest that control of B. rubens may be equally warranted after one, two or three fires, but revegetation of native perennial plants is most warranted following multiple fires. These results are valid within the scope of this study, which is defined as relatively short term vegetation responses (???14 years) to short fire return intervals (6.3 and 7.3 years for the two and three fire frequency levels) within creosote bush scrub of the Mojave Desert. ?? 2012 IAWF.

Choledochoscopic high-frequency needle-knife electrotomy as an effective treatment for intrahepatic biliary strictures.

PubMed

Yang, Yu-Long; Zhang, Cheng; Zhao, Gang; Wu, Ping; Ma, Yue-Feng; Zhang, Hong-Wei; Shi, Li-Jun; Li, Jing-Yi; Lin, Mei-Ju; Yang, Shi-Ming; Lv, Yi

2015-09-01

Hepatolithiasis is associated with the presence of intrahepatic biliary strictures, and balloon dilatation is the main approach. However, this method is difficult to implement if the bile duct distal to the stricture is blocked by stones. Therefore, alternative methods need to be explored to effectively treat hepatolithiasis. The aim of this study is to investigate the feasibility and effectiveness of choledochoscopic high-frequency needle-knife electrotomy for the treatment of intrahepatic biliary strictures. Clinical data of 58 patients suffering from intrahepatic bile duct strictures from January 2011 to January 2013 were retrospectively analyzed. Choledochoscopic electrotomy was used to resolve the strictures. One hundred thirty-four sites of intrahepatic bile duct strictures were discovered. The average operating time of electrotomy is 5.6 min (range, 1 ∼ 15 min). Structured bile duct tissue bleeding occurred in eight sites (8/134, 6.0%) but were resolved by endoscopic high-frequency electric cautery. After the operations, 14 cases of cholangitis (14/58, 24.1%), three cases of delayed hemobilia, one case of liver abscess (1/58, 1.7%), and seven cases of stenting exodus (7/58, 12.1%) were observed despite conservative treatment and stenting reset. The average supporting time was 7.0 months (6 ∼ 9 months). No abnormal bile duct structure or presence of stone was found according to choledochoscopy. The follow-up period ranged from 12 to 48 months. Hepatolithiasis recurred in five (5/58, 8.6%) patients, and the cumulative recurrent probability of intrahepatic bile duct stricture was 5.2% (7/134). Choledochoscopic high-frequency needle-knife electrotomy could be considered as a simple, safe, and effective complementary approach for treating intrahepatic biliary strictures. © 2015 Journal of Gastroenterology and Hepatology Foundation and Wiley Publishing Asia Pty Ltd.

High-frequency graphene voltage amplifier.

PubMed

Han, Shu-Jen; Jenkins, Keith A; Valdes Garcia, Alberto; Franklin, Aaron D; Bol, Ageeth A; Haensch, Wilfried

2011-09-14

While graphene transistors have proven capable of delivering gigahertz-range cutoff frequencies, applying the devices to RF circuits has been largely hindered by the lack of current saturation in the zero band gap graphene. Herein, the first high-frequency voltage amplifier is demonstrated using large-area chemical vapor deposition grown graphene. The graphene field-effect transistor (GFET) has a 6-finger gate design with gate length of 500 nm. The graphene common-source amplifier exhibits ∼5 dB low frequency gain with the 3 dB bandwidth greater than 6 GHz. This first AC voltage gain demonstration of a GFET is attributed to the clear current saturation in the device, which is enabled by an ultrathin gate dielectric (4 nm HfO(2)) of the embedded gate structures. The device also shows extrinsic transconductance of 1.2 mS/μm at 1 V drain bias, the highest for graphene FETs using large-scale graphene reported to date.

High frequency pressure oscillator for microcryocoolers.

PubMed

Vanapalli, S; ter Brake, H J M; Jansen, H V; Zhao, Y; Holland, H J; Burger, J F; Elwenspoek, M C

2008-04-01

Microminiature pulse tube cryocoolers should operate at a frequency of an order higher than the conventional macro ones because the pulse tube cryocooler operating frequency scales inversely with the square of the pulse tube diameter. In this paper, the design and experiments of a high frequency pressure oscillator is presented with the aim to power a micropulse tube cryocooler operating between 300 and 80 K, delivering a cooling power of 10 mW. Piezoelectric actuators operate efficiently at high frequencies and have high power density making them good candidates as drivers for high frequency pressure oscillator. The pressure oscillator described in this work consists of a membrane driven by a piezoelectric actuator. A pressure ratio of about 1.11 was achieved with a filling pressure of 2.5 MPa and compression volume of about 22.6 mm(3) when operating the actuator with a peak-to-peak sinusoidal voltage of 100 V at a frequency of 1 kHz. The electrical power input was 2.73 W. The high pressure ratio and low electrical input power at high frequencies would herald development of microminiature cryocoolers.

High frequency pressure oscillator for microcryocoolers

NASA Astrophysics Data System (ADS)

Vanapalli, S.; ter Brake, H. J. M.; Jansen, H. V.; Zhao, Y.; Holland, H. J.; Burger, J. F.; Elwenspoek, M. C.

2008-04-01

Microminiature pulse tube cryocoolers should operate at a frequency of an order higher than the conventional macro ones because the pulse tube cryocooler operating frequency scales inversely with the square of the pulse tube diameter. In this paper, the design and experiments of a high frequency pressure oscillator is presented with the aim to power a micropulse tube cryocooler operating between 300 and 80K, delivering a cooling power of 10mW. Piezoelectric actuators operate efficiently at high frequencies and have high power density making them good candidates as drivers for high frequency pressure oscillator. The pressure oscillator described in this work consists of a membrane driven by a piezoelectric actuator. A pressure ratio of about 1.11 was achieved with a filling pressure of 2.5MPa and compression volume of about 22.6mm3 when operating the actuator with a peak-to-peak sinusoidal voltage of 100V at a frequency of 1kHz. The electrical power input was 2.73W. The high pressure ratio and low electrical input power at high frequencies would herald development of microminiature cryocoolers.

Extrinsic and Intrinsic Frequency Dispersion of High-k Materials in Capacitance-Voltage Measurements

PubMed Central

Tao, J.; Zhao, C.Z.; Zhao, C.; Taechakumput, P.; Werner, M.; Taylor, S.; Chalker, P. R.

2012-01-01

In capacitance-voltage (C-V) measurements, frequency dispersion in high-k dielectrics is often observed. The frequency dependence of the dielectric constant (k-value), that is the intrinsic frequency dispersion, could not be assessed before suppressing the effects of extrinsic frequency dispersion, such as the effects of the lossy interfacial layer (between the high-k thin film and silicon substrate) and the parasitic effects. The effect of the lossy interfacial layer on frequency dispersion was investigated and modeled based on a dual frequency technique. The significance of parasitic effects (including series resistance and the back metal contact of the metal-oxide-semiconductor (MOS) capacitor) on frequency dispersion was also studied. The effect of surface roughness on frequency dispersion is also discussed. After taking extrinsic frequency dispersion into account, the relaxation behavior can be modeled using the Curie-von Schweidler (CS) law, the Kohlrausch-Williams-Watts (KWW) relationship and the Havriliak-Negami (HN) relationship. Dielectric relaxation mechanisms are also discussed. PMID:28817021

Effect of high power low frequency ultrasound processing on the stability of lycopene.

PubMed

Oliveira, Valéria S; Rodrigues, Sueli; Fernandes, Fabiano A N

2015-11-01

The stability of lycopene was evaluated after application of high power low frequency ultrasound. The study was carried out on a solution containing pure lycopene to evaluate the direct effect of ultrasound on lycopene and on tomato purée to evaluate the direct and indirect effects of ultrasound application within a food matrix. Power densities ranging from 55 to 5000 W/L and temperatures ranging from 23°C (ambient) to 60°C were evaluated. The experiments on pure lycopene showed that the application of ultrasound did not have any direct effect over lycopene. However, the retention of lycopene in tomato puree has decreased indicating an indirect effect on lycopene stability caused by high concentration of hydrogen peroxide and the activation of peroxidase enzymes leading to the reduction of ascorbic acid and its regenerative action towards lycopene. Copyright © 2015 Elsevier B.V. All rights reserved.

The Effects of Visual Complexity for Japanese Kanji Processing with High and Low Frequencies

ERIC Educational Resources Information Center

Tamaoka, Katsuo; Kiyama, Sachiko

2013-01-01

The present study investigated the effects of visual complexity for kanji processing by selecting target kanji from different stroke ranges of visually simple (2-6 strokes), medium (8-12 strokes), and complex (14-20 strokes) kanji with high and low frequencies. A kanji lexical decision task in Experiment 1 and a kanji naming task in Experiment 2…

Binaural beats at high frequencies.

PubMed

McFadden, D; Pasanen, E G

1975-10-24

Binaural beats have long been believed to be audible only at low frequencies, but an interaction reminiscent of a binaural beat can sometimes be heard when different two-tone complexes of high frequency are presented to the two ears. The primary requirement is that the frequency separation in the complex at one ear be slightly different from that in the other--that is, that there be a small interaural difference in the envelope periodicities. This finding is in accord with other recent demonstrations that the auditory system is not deaf to interaural time differences at high frequencies.

Assimilation of GPM GMI Rainfall Product with WRF GSI

NASA Technical Reports Server (NTRS)

Li, Xuanli; Mecikalski, John; Zavodsky, Bradley

2015-01-01

The Global Precipitation Measurement (GPM) is an international mission to provide next-generation observations of rain and snow worldwide. The GPM built on Tropical Rainfall Measuring Mission (TRMM) legacy, while the core observatory will extend the observations to higher latitudes. The GPM observations can help advance our understanding of precipitation microphysics and storm structures. Launched on February 27th, 2014, the GPM core observatory is carrying advanced instruments that can be used to quantify when, where, and how much it rains or snows around the world. Therefore, the use of GPM data in numerical modeling work is a new area and will have a broad impact in both research and operational communities. The goal of this research is to examine the methodology of assimilation of the GPM retrieved products. The data assimilation system used in this study is the community Gridpoint Statistical Interpolation (GSI) system for the Weather Research and Forecasting (WRF) model developed by the Development Testbed Center (DTC). The community GSI system runs in independently environment, yet works functionally equivalent to operational centers. With collaboration with the NASA Short-term Prediction Research and Transition (SPoRT) Center, this research explores regional assimilation of the GPM products with case studies. Our presentation will highlight our recent effort on the assimilation of the GPM product 2AGPROFGMI, the retrieved Microwave Imager (GMI) rainfall rate data for initializing a real convective storm. WRF model simulations and storm scale data assimilation experiments will be examined, emphasizing both model initialization and short-term forecast of precipitation fields and processes. In addition, discussion will be provided on the development of enhanced assimilation procedures in the GSI system with respect to other GPM products. Further details of the methodology of data assimilation, preliminary result and test on the impact of GPM data and the

ALMA High Frequency Techniques

NASA Astrophysics Data System (ADS)

Meyer, J. D.; Mason, B.; Impellizzeri, V.; Kameno, S.; Fomalont, E.; Chibueze, J.; Takahashi, S.; Remijan, A.; Wilson, C.; ALMA Science Team

2015-12-01

The purpose of the ALMA High Frequency Campaign is to improve the quality and efficiency of science observing in Bands 8, 9, and 10 (385-950 GHz), the highest frequencies available to the ALMA project. To this end, we outline observing modes which we have demonstrated to improve high frequency calibration for the 12m array and the ACA, and we present the calibration of the total power antennas at these frequencies. Band-to-band (B2B) transfer and bandwidth switching (BWSW), techniques which improve the speed and accuracy of calibration at the highest frequencies, are most necessary in Bands 8, 9, and 10 due to the rarity of strong calibrators. These techniques successfully enable increased signal-to-noise on the calibrator sources (and better calibration solutions) by measuring the calibrators at lower frequencies (B2B) or in wider bandwidths (BWSW) compared to the science target. We have also demonstrated the stability of the bandpass shape to better than 2.4% for 1 hour, hidden behind random noise, in Band 9. Finally, total power observing using the dual sideband receivers in Bands 9 and 10 requires the separation of the two sidebands; this procedure has been demonstrated in Band 9 and is undergoing further testing in Band 10.

Active Control of High-Speed Free Jets Using High-Frequency Excitation

NASA Astrophysics Data System (ADS)

Upadhyay, Puja

Control of aerodynamic noise generated by high-performance jet engines continues to remain a serious problem for the aviation community. Intense low frequency noise produced by large-scale coherent structures is known to dominate acoustic radiation in the aft angles. A tremendous amount of research effort has been dedicated towards the investigation of many passive and active flow control strategies to attenuate jet noise, while keeping performance penalties to a minimum. Unsteady excitation, an active control technique, seeks to modify acoustic sources in the jet by leveraging the naturally-occurring flow instabilities in the shear layer. While excitation at a lower range of frequencies that scale with the dynamics of large-scale structures, has been attempted by a number of studies, effects at higher excitation frequencies remain severely unexplored. One of the major limitations stems from the lack of appropriate flow control devices that have sufficient dynamic response and/or control authority to be useful in turbulent flows, especially at higher speeds. To this end, the current study seeks to fulfill two main objectives. First, the design and characterization of two high-frequency fluidic actuators (25 and 60 kHz) are undertaken, where the target frequencies are guided by the dynamics of high-speed free jets. Second, the influence of high-frequency forcing on the aeroacoustics of high-speed jets is explored in some detail by implementing the nominally 25 kHz actuator on a Mach 0.9 (Re D = 5 x 105) free jet flow field. Subsequently, these findings are directly compared to the results of steady microjet injection experiments performed in the same rig and to prior jet noise control studies, where available. Finally, limited acoustic measurements were also performed by implementing the nominally 25 kHz actuators on jets at higher Mach numbers, including shock containing jets, and elevated temperatures. Using lumped element modeling as an initial guide, the current

High frequency inductive lamp and power oscillator

DOEpatents

MacLennan, Donald A.; Dymond, Jr., Lauren E.; Gitsevich, Aleksandr; Grimm, William G.; Kipling, Kent; Kirkpatrick, Douglas A.; Ola, Samuel A.; Simpson, James E.; Trimble, William C.; Tsai, Peter; Turner, Brian P.

2001-01-01

A high frequency inductively coupled electrodeless lamp includes an excitation coil with an effective electrical length which is less than one half wavelength of a driving frequency applied thereto, preferably much less. The driving frequency may be greater than 100 MHz and is preferably as high as 915 MHz. Preferably, the excitation coil is configured as a non-helical, semi-cylindrical conductive surface having less than one turn, in the general shape of a wedding ring. At high frequencies, the current in the coil forms two loops which are spaced apart and parallel to each other. Configured appropriately, the coil approximates a Helmholtz configuration. The lamp preferably utilizes an bulb encased in a reflective ceramic cup with a pre-formed aperture defined therethrough. The ceramic cup may include structural features to aid in alignment and I or a flanged face to aid in thermal management. The lamp head is preferably an integrated lamp head comprising a metal matrix composite surrounding an insulating ceramic with the excitation integrally formed on the ceramic. A novel solid-state oscillator preferably provides RF power to the lamp. The oscillator is a single active element device capable of providing over 70 watts of power at over 70% efficiency. Various control circuits may be employed to adjust the driving frequency of the oscillator.

High frequency inductive lamp and power oscillator

DOEpatents

MacLennan, Donald A.; Turner, Brian P.; Dolan, James T.; Kirkpatrick, Douglas A.; Leng, Yongzhang

2000-01-01

A high frequency inductively coupled electrodeless lamp includes an excitation coil with an effective electrical length which is less than one half wavelength of a driving frequency applied thereto, preferably much less. The driving frequency may be greater than 100 MHz and is preferably as high as 915 MHz. Preferably, the excitation coil is configured as a non-helical, semi-cylindrical conductive surface having less than one turn, in the general shape of a wedding ring. At high frequencies, the current in the coil forms two loops which are spaced apart and parallel to each other. Configured appropriately, the coil approximates a Helmholtz configuration. The lamp preferably utilizes an bulb encased in a reflective ceramic cup with a pre-formed aperture defined therethrough. The ceramic cup may include structural features to aid in alignment and/or a flanged face to aid in thermal management. The lamp head is preferably an integrated lamp head comprising a metal matrix composite surrounding an insulating ceramic with the excitation integrally formed on the ceramic. A novel solid-state oscillator preferably provides RF power to the lamp. The oscillator is a single active element device capable of providing over 70 watts of power at over 70% efficiency. Various control circuits may be employed to match the driving frequency of the oscillator to a plurality of tuning states of the lamp.

Effect of Interfacial characteristics of metal clad polymeric substrates on electrical high frequency interconnection performance

NASA Technical Reports Server (NTRS)

Bhasin, K. B.; Romanofsky, R. R.; Ponchak, G. E.; Liu, D. C.

1984-01-01

Etched metallic conductor lines on metal clad polymeric substrates are used for electronic component interconnections. Significant signal losses are observed for microstrip conductor lines used for interconnecting high frequency devices. At these frequencies, the electronic signal travels closer to the metal-polymer interface due to the skin effect. Copper-teflon interfaces were characterized by scanning electron microscopy (SEM) and Auger electron spectroscopy (AES) to determine the interfacial properties. Data relating roughness of the copper film to signal losses was compared to theory. Films used to enhance adhesion are found, to contribute to these losses.

Parametric Effects of Word Frequency in Memory for Mixed Frequency Lists

ERIC Educational Resources Information Center

Lohnas, Lynn J.; Kahana, Michael J.

2013-01-01

The "word frequency paradox" refers to the finding that low frequency words are better recognized than high frequency words yet high frequency words are better recalled than low frequency words. Rather than comparing separate groups of low and high frequency words, we sought to quantify the functional relation between word frequency and…

Effects of degree and configuration of hearing loss on the contribution of high- and low-frequency speech information to bilateral speech understanding

PubMed Central

Hornsby, Benjamin W. Y.; Johnson, Earl E.; Picou, Erin

2011-01-01

Objectives The purpose of this study was to examine the effects of degree and configuration of hearing loss on the use of, and benefit from, information in amplified high- and low-frequency speech presented in background noise. Design Sixty-two adults with a wide range of high- and low-frequency sensorineural hearing loss (5–115+ dB HL) participated. To examine the contribution of speech information in different frequency regions, speech understanding in noise was assessed in multiple low- and high-pass filter conditions, as well as a band-pass (713–3534 Hz) and wideband (143–8976 Hz) condition. To increase audibility over a wide frequency range, speech and noise were amplified based on each individual’s hearing loss. A stepwise multiple linear regression approach was used to examine the contribution of several factors to 1) absolute performance in each filter condition and 2) the change in performance with the addition of amplified high- and low-frequency speech components. Results Results from the regression analysis showed that degree of hearing loss was the strongest predictor of absolute performance for low- and high-pass filtered speech materials. In addition, configuration of hearing loss affected both absolute performance for severely low-pass filtered speech and benefit from extending high-frequency (3534–8976 Hz) bandwidth. Specifically, individuals with steeply sloping high-frequency losses made better use of low-pass filtered speech information than individuals with similar low-frequency thresholds but less high-frequency loss. In contrast, given similar high-frequency thresholds, individuals with flat hearing losses received more benefit from extending high-frequency bandwidth than individuals with more sloping losses. Conclusions Consistent with previous work, benefit from speech information in a given frequency region generally decreases as degree of hearing loss in that frequency region increases. However, given a similar degree of loss

BK potassium channels facilitate high-frequency firing and cause early spike frequency adaptation in rat CA1 hippocampal pyramidal cells

PubMed Central

Gu, Ning; Vervaeke, Koen; Storm, Johan F

2007-01-01

Neuronal potassium (K+) channels are usually regarded as largely inhibitory, i.e. reducing excitability. Here we show that BK-type calcium-activated K+ channels enhance high-frequency firing and cause early spike frequency adaptation in neurons. By combining slice electrophysiology and computational modelling, we investigated functions of BK channels in regulation of high-frequency firing in rat CA1 pyramidal cells. Blockade of BK channels by iberiotoxin (IbTX) selectively reduced the initial discharge frequency in response to strong depolarizing current injections, thus reducing the early spike frequency adaptation. IbTX also blocked the fast afterhyperpolarization (fAHP), slowed spike rise and decay, and elevated the spike threshold. Simulations with a computational model of a CA1 pyramidal cell confirmed that the BK channel-mediated rapid spike repolarization and fAHP limits activation of slower K+ channels (in particular the delayed rectifier potassium current (IDR)) and Na+ channel inactivation, whereas M-, sAHP- or SK-channels seem not to be important for the early facilitating effect. Since the BK current rapidly inactivates, its facilitating effect diminishes during the initial discharge, thus producing early spike frequency adaptation by an unconventional mechanism. This mechanism is highly frequency dependent. Thus, IbTX had virtually no effect at spike frequencies < 40 Hz. Furthermore, extracellular field recordings demonstrated (and model simulations supported) that BK channels contribute importantly to high-frequency burst firing in response to excitatory synaptic input to distal dendrites. These results strongly support the idea that BK channels play an important role for early high-frequency, rapidly adapting firing in hippocampal pyramidal neurons, thus promoting the type of bursting that is characteristic of these cells in vivo, during behaviour. PMID:17303637

Testing the high turbulence level breakdown of low-frequency gyrokinetics against high-frequency cyclokinetic simulations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Deng, Zhao, E-mail: zhao.deng@foxmail.com; Waltz, R. E.

2015-05-15

This paper presents numerical simulations of the nonlinear cyclokinetic equations in the cyclotron harmonic representation [R. E. Waltz and Zhao Deng, Phys. Plasmas 20, 012507 (2013)]. Simulations are done with a local flux-tube geometry and with the parallel motion and variation suppressed using a newly developed rCYCLO code. Cyclokinetic simulations dynamically follow the high-frequency ion gyro-phase motion which is nonlinearly coupled into the low-frequency drift-waves possibly interrupting and suppressing gyro-averaging and increasing the transport over gyrokinetic levels. By comparing the more fundamental cyclokinetic simulations with the corresponding gyrokinetic simulations, the breakdown of gyrokinetics at high turbulence levels is quantitatively testedmore » over a range of relative ion cyclotron frequency 10 < Ω*{sup  }< 100 where Ω*{sup  }= 1/ρ*, and ρ* is the relative ion gyroradius. The gyrokinetic linear mode rates closely match the cyclokinetic low-frequency rates for Ω*{sup  }> 5. Gyrokinetic transport recovers cyclokinetic transport at high relative ion cyclotron frequency (Ω*{sup  }≥ 50) and low turbulence level as required. Cyclokinetic transport is found to be lower than gyrokinetic transport at high turbulence levels and low-Ω* values with stable ion cyclotron (IC) modes. The gyrokinetic approximation is found to break down when the density perturbations exceed 20%. For cyclokinetic simulations with sufficiently unstable IC modes and sufficiently low Ω*{sup  }∼ 10, the high-frequency component of cyclokinetic transport level can exceed the gyrokinetic transport level. However, the low-frequency component of the cyclokinetic transport and turbulence level does not exceed that of gyrokinetics. At higher and more physically relevant Ω*{sup  }≥ 50 values and physically realistic IC driving rates, the low-frequency component of the cyclokinetic transport and turbulence level is still smaller than that of

Mid- to high-frequency noise from high-speed boats and its potential impacts on humpback dolphins.

PubMed

Li, Songhai; Wu, Haiping; Xu, Youhou; Peng, Chongwei; Fang, Liang; Lin, Mingli; Xing, Luru; Zhang, Peijun

2015-08-01

The impact of noise made by vessels on marine animals has come under increased concern. However, most measurements on noise from vessels have only taken into account the low-frequency components. For cetaceans operating in the mid- and high-frequencies, such as the Indo-Pacific humpback dolphin (Sousa chinensis), mid- to high-frequency noise components may be of more concern, in terms of their potential impacts. In this study, noise made by a small high-speed boat was recorded using a broadband recording system in a dolphin watching area focusing on the effects on humpback dolphins in Sanniang Bay, China. The high-speed boat produced substantial mid- to high-frequency noise components with frequencies to >100 kHz, measured at three speeds: ∼40, 30, and 15 km/h. The noise from the boat raised the ambient noise levels from ∼5 to 47 decibels (dB) root-mean-square (rms) across frequency bands ranging from 1 to 125 kHz at a distance of 20 to 85 m, with louder levels recorded at higher speeds and at closer distances. To conclude, the noise produced by the small high-speed boat could be heard by Sousa chinensis and therefore potentially had adverse effects on the dolphins.

Study on regeneration effect and mechanism of high-frequency ultrasound on biological activated carbon.

PubMed

Sun, Zhehao; Liu, Cheng; Cao, Zhen; Chen, Wei

2018-06-01

High frequency ultrasonic radiation technology was developed as a novel and efficient means of regenerating spent biological activated carbon (BAC) used in drinking water treatment plants (DWTPs). The results of this study indicated that high frequency ultrasonic treatment could recover the spent BAC, to some extent, with the following optimal conditions: a frequency of 400 kHz, sonication power of 60 W, water temperature of 30 °C, and sonication time of 6 min. Under the above conditions, the iodine value increased from 300 mg/g to 409 mg/g, the volume of total pores and micropores increased from 0.2600 cm 3 /g and 0.1779 cm 3 /g to 0.3560 cm 3 /g and 0.2662 cm 3 /g, respectively; the specific surface area of micropores and the mean pore diameter expanded from 361.15 m 2 /g and 2.0975 nm to 449.92 m 2 /g and 2.1268 nm, respectively. The biological activity increased from 0.0297 mgO 2 /gC·h to 0.0521 mgO 2 /gC·h, while the biomass decreased from 203 nmolP/gC to 180 nmolP/gC. The results of high throughput 16S rRNA gene amplicon sequencing showed that microorganisms such as Clostridia and Nitrospira were markedly decreased due to high frequency ultrasound. The method used in this study caused the inhibition of certain carbon-attached microbials resulting in a negative effect on the removal rate of ammonia-N during the initial stage of the long-term reuse operation. The removal of UV254 and atrazine were restored from 8.1% and 55% to 21% and 76%, respectively. Copyright © 2018 Elsevier B.V. All rights reserved.

High power, high frequency helix TWT's

NASA Astrophysics Data System (ADS)

Sloley, H. J.; Willard, J.; Paatz, S. R.; Keat, M. J.

The design and performance characteristics of a 34-GHz pulse tube capable of 75 W peak power output at 30 percent duty cycle and a broadband CW tube are presented. Particular attention is given to the engineering problems encountered during the development of the tubes, including the suppression of backward wave oscillation, the design of electron guns for small-diameter high-current beams, and the thermal capability of small helix structures. The discussion also covers the effects of various design parameters and choice of engineering materials on the ultimate practical limit of power and gain at the operating frequencies. Measurements are presented for advanced experimental tubes.

High-frequency energy in singing and speech

NASA Astrophysics Data System (ADS)

Monson, Brian Bruce

While human speech and the human voice generate acoustical energy up to (and beyond) 20 kHz, the energy above approximately 5 kHz has been largely neglected. Evidence is accruing that this high-frequency energy contains perceptual information relevant to speech and voice, including percepts of quality, localization, and intelligibility. The present research was an initial step in the long-range goal of characterizing high-frequency energy in singing voice and speech, with particular regard for its perceptual role and its potential for modification during voice and speech production. In this study, a database of high-fidelity recordings of talkers was created and used for a broad acoustical analysis and general characterization of high-frequency energy, as well as specific characterization of phoneme category, voice and speech intensity level, and mode of production (speech versus singing) by high-frequency energy content. Directionality of radiation of high-frequency energy from the mouth was also examined. The recordings were used for perceptual experiments wherein listeners were asked to discriminate between speech and voice samples that differed only in high-frequency energy content. Listeners were also subjected to gender discrimination tasks, mode-of-production discrimination tasks, and transcription tasks with samples of speech and singing that contained only high-frequency content. The combination of these experiments has revealed that (1) human listeners are able to detect very subtle level changes in high-frequency energy, and (2) human listeners are able to extract significant perceptual information from high-frequency energy.

Differential effects of tactile high- and low-frequency stimulation on tactile discrimination in human subjects.

PubMed

Ragert, Patrick; Kalisch, Tobias; Bliem, Barbara; Franzkowiak, Stephanie; Dinse, Hubert R

2008-01-23

Long-term potentiation (LTP) and long-term depression (LTD) play important roles in mediating activity-dependent changes in synaptic transmission and are believed to be crucial mechanisms underlying learning and cortical plasticity. In human subjects, however, the lack of adequate input stimuli for the induction of LTP and LTD makes it difficult to study directly the impact of such protocols on behavior. Using tactile high- and low-frequency stimulation protocols in humans, we explored the potential of such protocols for the induction of perceptual changes. We delivered tactile high-frequency and low-frequency stimuli (t-HFS, t-LFS) to skin sites of approximately 50 mm2 on the tip of the index finger. As assessed by 2-point discrimination, we demonstrate that 20 minutes of t-HFS improved tactile discrimination, while t-LFS impaired performance. T-HFS-effects were stable for at least 24 hours whereas t-LFS-induced changes recovered faster. While t-HFS changes were spatially very specific with no changes on the neighboring fingers, impaired tactile performance after t-LFS was also observed on the right middle-finger. A central finding was that for both t-LFS and t-HFS perceptual changes were dependent on the size of the stimulated skin area. No changes were observed when the stimulated area was very small (< 1 mm2) indicating special requirements for spatial summation. Our results demonstrate differential effects of such protocols in a frequency specific manner that might be related to LTP- and LTD-like changes in human subjects.

Global high-frequency source imaging accounting for complexity in Green's functions

NASA Astrophysics Data System (ADS)

Lambert, V.; Zhan, Z.

2017-12-01

The general characterization of earthquake source processes at long periods has seen great success via seismic finite fault inversion/modeling. Complementary techniques, such as seismic back-projection, extend the capabilities of source imaging to higher frequencies and reveal finer details of the rupture process. However, such high frequency methods are limited by the implicit assumption of simple Green's functions, which restricts the use of global arrays and introduces artifacts (e.g., sweeping effects, depth/water phases) that require careful attention. This motivates the implementation of an imaging technique that considers the potential complexity of Green's functions at high frequencies. We propose an alternative inversion approach based on the modest assumption that the path effects contributing to signals within high-coherency subarrays share a similar form. Under this assumption, we develop a method that can combine multiple high-coherency subarrays to invert for a sparse set of subevents. By accounting for potential variability in the Green's functions among subarrays, our method allows for the utilization of heterogeneous global networks for robust high resolution imaging of the complex rupture process. The approach also provides a consistent framework for examining frequency-dependent radiation across a broad frequency spectrum.

Interdigital pair bonding for high frequency (20-50 MHz) ultrasonic composite transducers.

PubMed

Liu, R; Harasiewicz, K A; Foster, F S

2001-01-01

Interdigital pair bonding is a novel methodology that enables the fabrication of high frequency piezoelectric composites with high volume fractions of the ceramic phase. This enhancement in ceramic volume fraction significantly reduces the dimensional scale of the epoxy phase and increases the related effective physical parameters of the composite, such as dielectric constant and the longitudinal sound velocity, which are major concerns in the development of high frequency piezoelectric composites. In this paper, a method called interdigital pair bonding (IPB) is used to prepare 1-3 piezoelectric composite with a pitch of 40 microns, a kerf of 4 microns, and a ceramic volume fraction of 81%. The composites prepared in this fashion exhibited a very pure thickness-mode resonance up to a frequency of 50 MHz. Unlike the 2-2 piezoelectric composites with the same ceramic and epoxy scales developed earlier, the anticipated lateral modes between 50 to 100 MHz were not observed in the current 1-3 composites. The mechanisms for the elimination of the lateral modes at high frequency are discussed. The effective electromechanical coupling coefficient of the composite was 0.72 at a frequency of 50 MHz. The composites showed a high longitudinal sound velocity of 4300 m/s and a high clamped dielectric constant of 1111 epsilon 0, which will benefit the development of high frequency ultrasonic transducers and especially high frequency transducer arrays for medical imaging.

Analysis of transistor and snubber turn-off dynamics in high-frequency high-voltage high-power converters

NASA Technical Reports Server (NTRS)

Wilson, P. M.; Wilson, T. G.; Owen, H. A., Jr.

1982-01-01

Dc to dc converters which operate reliably and efficiently at switching frequencies high enough to effect substantial reductions in the size and weight of converter energy storage elements are studied. A two winding current or voltage stepup (buck boost) dc-to-dc converter power stage submodule designed to operate in the 2.5-kW range, with an input voltage range of 110 to 180 V dc, and an output voltage of 250 V dc is emphasized. In order to assess the limitations of present day component and circuit technologies, a design goal switching frequency of 10 kHz was maintained. The converter design requirements represent a unique combination of high frequency, high voltage, and high power operation. The turn off dynamics of the primary circuit power switching transistor and its associated turn off snubber circuitry are investigated.

Analysis of transistor and snubber turn-off dynamics in high-frequency high-voltage high-power converters

NASA Astrophysics Data System (ADS)

Wilson, P. M.; Wilson, T. G.; Owen, H. A., Jr.

Dc to dc converters which operate reliably and efficiently at switching frequencies high enough to effect substantial reductions in the size and weight of converter energy storage elements are studied. A two winding current or voltage stepup (buck boost) dc-to-dc converter power stage submodule designed to operate in the 2.5-kW range, with an input voltage range of 110 to 180 V dc, and an output voltage of 250 V dc is emphasized. In order to assess the limitations of present day component and circuit technologies, a design goal switching frequency of 10 kHz was maintained. The converter design requirements represent a unique combination of high frequency, high voltage, and high power operation. The turn off dynamics of the primary circuit power switching transistor and its associated turn off snubber circuitry are investigated.

High-frequency - Spinal Cord Stimulation.

PubMed

Rapcan, R; Mlaka, J; Venglarcik, M; Vinklerova, V; Gajdos, M; Illes, R

2015-01-01

Our clinical experience with high - frequency SCS for FBSS in patients with predominant low back pain is presented. After a trial period, 100 % (21 out of 21) of patients with FBSS with predominant low back pain reported a significant improvement in visual analog scale (VAS) pain score and underwent permanent implantation of the high - frequency SCS system. SCS trials lasted 7-14 days (median 9 days). SCS leads were mostly positioned at the T8-10 or T8-12 vertebral levels . We used both single and dual lead placement. VAS, patient satisfaction, patient performance status, opioid consumption and complication rate were assessed for the period of 12 months. The mean VAS score before implantation (8.7) compared to VAS 12 months after implantation (4.0) was significantly lower (CI95[3.9-5.4], p < 0.001). There was a significant improvement in performance status when comparing PS before implantation (3.0) and 12 months after implantation (1.8) (CI95[0.9-1.6], p < 0.001). The mean patient satisfaction scores (PSS) did not differ throughout the whole one year follow-up period. Our group of 21 patients with implanted high - frequency SCS systems reported significant low back pain and leg pain relief within the period of 12 months as well as significant improvement in their performance status. We had a special subgroup of 5 patients with regular change of frequencies between high frequency and conventional frequency (with paresthesia) also with significant leg and low back pain relief (Tab. 2, Fig. 1, Ref. 8). Text in PDF www.elis.sk.

Effect of temperature- and frequency-dependent dynamic properties of rail pads on high-speed vehicle-track coupled vibrations

NASA Astrophysics Data System (ADS)

Wei, Kai; Wang, Feng; Wang, Ping; Liu, Zi-xuan; Zhang, Pan

2017-03-01

315 Hz, which are the dominant frequencies of ground vibration acceleration and rolling noise (or bridge noise) caused by high-speed railways respectively. Since the fractional derivative value of the adopted rubber primary suspension, unlike the tested rail pad, is very close to 1, its frequency-dependent dynamic performance has little effect on high-speed vehicle-track coupled vibration responses.

Effectiveness of an acoustical product in reducing high-frequency sound within unoccupied incubators.

PubMed

Kellam, Barbara; Bhatia, Jatinder

2009-08-01

Few noise measurement studies in the neonatal intensive care unit have reported sound frequencies within incubators. Sound frequencies within incubators are markedly different from sound frequencies within the gravid uterus. This article reports the results of sound spectral analysis (SSA) within unoccupied incubators under control and treatment conditions. SSA indicated that acoustical foam panels (treatment condition) markedly reduced sound frequencies > or =500 Hz when compared with the control condition. The main findings of this study (a) illustrate the need to monitor high-frequency sound within incubators and (b) indicate one method to reduce atypical sound exposure within incubators.

Investigations on structural and giant magneto impedance properties of Zn3(VO4)2 nanorods

NASA Astrophysics Data System (ADS)

Malaidurai, M.; Bulusu, Venkat; De, Sourodeep; Thangavel, R.

2018-05-01

In this paper, we successfully synthesized Zn3(VO4)2 novel nanorods by hydrothermal method. As mixed phase of Zn3(VO4)2 structural and phase transformations were monitored in crystal lattice with different ionic strength by X-ray diffraction(XRD). The Zn3(VO4)2 thin film formation validated through qualitative and quantitative analysis by FESEM and it is clearly depicted the formation of the Zn3(VO4)2 nanorods varied from ˜100nm in lengths and ˜30 nm in widths. The Zn precursor's anions directly influence the composition and shape of the resultant hydrated Zn3(VO4)2. Impedance analysis were closely studied with Impedance-Frequency characterization, which was then followed by a dielectric measurement. The analysis of GMI effect was carried out with the help of the model equivalent circuit at low frequencies, constant phase element (CPE). GMI effect and the sensitivity are calculated for the sample by appling magnetic field and driving frequency in order to analyze the giant magnetoimpedance resistance of grain boundaries for spintronics applications.

High-frequency filtering of strong-motion records

USGS Publications Warehouse

Douglas, J.; Boore, D.M.

2011-01-01

The influence of noise in strong-motion records is most problematic at low and high frequencies where the signal to noise ratio is commonly low compared to that in the mid-spectrum. The impact of low-frequency noise (5 Hz) on computed pseudo-absolute response spectral accelerations (PSAs). In contrast to the case of low-frequency noise our analysis shows that filtering to remove high-frequency noise is only necessary in certain situations and that PSAs can often be used up to 100 Hz even if much lower high-cut corner frequencies are required to remove the noise. This apparent contradiction can be explained by the fact that PSAs are often controlled by ground accelerations associated with much lower frequencies than the natural frequency of the oscillator because path and site attenuation (often modelled by Q and κ, respectively) have removed the highest frequencies. We demonstrate that if high-cut filters are to be used, then their corner frequencies should be selected on an individual basis, as has been done in a few recent studies.

Masking of low-frequency signals by high-frequency, high-level narrow bands of noisea

PubMed Central

Patra, Harisadhan; Roup, Christina M.; Feth, Lawrence L.

2011-01-01

Low-frequency masking by intense high-frequency noise bands, referred to as remote masking (RM), was the first evidence to challenge energy-detection models of signal detection. Its underlying mechanisms remain unknown. RM was measured in five normal-hearing young-adults at 250, 350, 500, and 700 Hz using equal-power, spectrally matched random-phase noise (RPN) and low-noise noise (LNN) narrowband maskers. RM was also measured using equal-power, two-tone complex (TC2) and eight-tone complex (TC8). Maskers were centered at 3000 Hz with one or two equivalent rectangular bandwidths (ERBs). Masker levels varied from 80 to 95 dB sound pressure level in 5 dB steps. LNN produced negligible masking for all conditions. An increase in bandwidth in RPN yielded greater masking over a wider frequency region. Masking for TC2 was limited to 350 and 700 Hz for one ERB but shifted to only 700 Hz for two ERBs. A spread of masking to 500 and 700 Hz was observed for TC8 when the bandwidth was increased from one to two ERBs. Results suggest that high-frequency noise bands at high levels could generate significant low-frequency masking. It is possible that listeners experience significant RM due to the amplification of various competing noises that might have significant implications for speech perception in noise. PMID:21361445

Dual-frequency sound-absorbing metasurface based on visco-thermal effects with frequency dependence

NASA Astrophysics Data System (ADS)

Ryoo, H.; Jeon, W.

2018-03-01

We investigate theoretically an acoustic metasurface with a high absorption coefficient at two frequencies and design it from subwavelength structures. We propose the use of a two-dimensional periodic array of four Helmholtz resonators in two types to obtain a metasurface with nearly perfect sound absorption at given target frequencies via interactions between waves emanating from different resonators. By considering how fluid viscosity affects acoustic energy dissipation in the narrow necks of the Helmholtz resonators, we obtain effective complex-valued material properties that depend on frequency and on the geometrical parameters of the resonators. We furthermore derive the effective acoustic impedance of the metasurface from the effective material properties and calculate the absorption spectra from the theoretical model, which we compare with the spectra obtained from a finite-element simulation. As a practical application of the theoretical model, we derive empirical formulas for the geometrical parameters of a metasurface which would yield perfect absorption at a given frequency. While previous works on metasurfaces based on Helmholtz resonators aimed to absorb sound at single frequencies, we use optimization to design a metasurface composed of four different Helmholtz resonators to absorb sound at two distinct frequencies.

High frequency magnetostrictive transducers for waveguide applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Daw, Joshua Earl; Taylor, Steven Cheney; Rempe, Joy Lynn

A high frequency magnetostrictive transducer includes a magnetostrictive rod or wire inserted co-axially into a driving coil, wherein the driving coil includes a coil arrangement with a plurality of small coil segments along the magnetostrictive rod or wire; wherein frequency operation of the high frequency magnetostrictive transducer is controlled by a length of the small coil segments and a material type of the magnetostrictive rod or wire. This design of the high frequency magnetostrictive transducer retains the beneficial aspects of the magnetostrictive design, while reducing its primary drawback, lower frequency operation.

A Consistent Treatment of Microwave Emissivity and Radar Backscatter for Retrieval of Precipitation over Water Surfaces

NASA Technical Reports Server (NTRS)

Munchak, S. Joseph; Meneghini, Robert; Grecu, Mircea; Olson, William S.

2016-01-01

The Global Precipitation Measurement satellite's Microwave Imager (GMI) and Dual-frequency Precipitation Radar (DPR) are designed to provide the most accurate instantaneous precipitation estimates currently available from space. The GPM Combined Algorithm (CORRA) plays a key role in this process by retrieving precipitation profiles that are consistent with GMI and DPR measurements; therefore, it is desirable that the forward models in CORRA use the same geophysical input parameters. This study explores the feasibility of using internally consistent emissivity and surface backscatter cross-sectional (sigma(sub 0)) models for water surfaces in CORRA. An empirical model for DPR Ku and Ka sigma(sub 0) as a function of 10m wind speed and incidence angle is derived from GMI-only wind retrievals under clear-sky conditions. This allows for the sigma(sub 0) measurements, which are also influenced by path-integrated attenuation (PIA) from precipitation, to be used as input to CORRA and for wind speed to be retrieved as output. Comparisons to buoy data give a wind rmse of 3.7 m/s for Ku+GMI and 3.2 m/s for Ku+Ka+GMI retrievals under precipitation (compared to 1.3 m/s for clear-sky GMI-only), and there is a reduction in bias from GANAL background data (-10%) to the Ku+GMI (-3%) and Ku+Ka+GMI (-5%) retrievals. Ku+GMI retrievals of precipitation increase slightly in light (less than 1 mm/h) and decrease in moderate to heavy precipitation (greater than 1 mm/h). The Ku+Ka+GMI retrievals, being additionally constrained by the Ka reflectivity, increase only slightly in moderate and heavy precipitation at low wind speeds (less than 5 m/s) relative to retrievals using the surface reference estimate of PIA as input.

Modulating action of low frequency oscillations on high frequency instabilities in Hall thrusters

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liqiu, Wei, E-mail: weiliqiu@gmail.com, E-mail: weiliqiu@hit.edu.cn; Liang, Han; Ziyi, Yang

2015-02-07

It is found that the low frequency oscillations have modulating action on high frequency instabilities in Hall thrusters. The physical mechanism of this modulation is discussed and verified by numerical simulations. Theoretical analyses indicate that the wide-range fluctuations of plasma density and electric field associated with the low frequency oscillations affect the electron drift velocity and anomalous electron transport across the magnetic field. The amplitude and frequency of high frequency oscillations are modulated by low frequency oscillations, which show the periodic variation in the time scale of low frequency oscillations.

The effects of graded motor imagery and its components on phantom limb pain and disability in upper and lower limb amputees: a systematic review protocol.

PubMed

Limakatso, Katleho; Corten, Lieselotte; Parker, Romy

2016-09-01

Phantom limb pain (PLP) is characterized by the anatomical shifting of neighbouring somatosensory and motor areas into a deafferented cortical area of the brain contralateral to the amputated limb. It has been shown that maladaptive neuroplasticity is positively correlated to the perception of PLP in amputees. Recent studies support the use of graded motor imagery (GMI) and its component to alleviate the severity of PLP and disability. However, there is insufficient collective empirical evidence exploring the effectiveness of these treatment modalities in amputees with PLP. This systematic review will therefore explore the effects of GMI and its individual components on PLP and disability in upper and lower limb amputees. We will utilize a customized search strategy to search PubMed, Cochrane Central register of Controlled Trials, MEDLINE, Embase, PsycINFO, PEDro, Scopus, CINAHL, LILACS, DARE, Africa-Wide Information and Web of Science. We will also look at clinicaltrials.gov ( http://www.clinicaltrials.gov/ ), Pactr.gov ( http://www.pactr.org/ ) and EU Clinical trials register ( https://www.clinicaltrialsregister.eu/ ) for ongoing research. Two independent reviewers will screen articles for methodological validity. Thereafter, data from included studies will be extracted by two independent reviewers through a customized pre-set data extraction sheet. Studies with a comparable intervention and outcome measure will be pooled for meta-analysis. Studies with high heterogeneity will be analysed through random effects model. A narrative data analysis will be considered where there is insufficient data to perform a meta-analysis. Several studies investigating the effectiveness of GMI and its different components on PLP have drawn contrasting conclusions regarding the efficacy and applicability of GMI in clinical practice. This systematic review will therefore gather and critically appraise all relevant data, to generate a substantial conclusion and recommendations for

Effects of high-frequency damping on iterative convergence of implicit viscous solver

NASA Astrophysics Data System (ADS)

Nishikawa, Hiroaki; Nakashima, Yoshitaka; Watanabe, Norihiko

2017-11-01

This paper discusses effects of high-frequency damping on iterative convergence of an implicit defect-correction solver for viscous problems. The study targets a finite-volume discretization with a one parameter family of damped viscous schemes. The parameter α controls high-frequency damping: zero damping with α = 0, and larger damping for larger α (> 0). Convergence rates are predicted for a model diffusion equation by a Fourier analysis over a practical range of α. It is shown that the convergence rate attains its minimum at α = 1 on regular quadrilateral grids, and deteriorates for larger values of α. A similar behavior is observed for regular triangular grids. In both quadrilateral and triangular grids, the solver is predicted to diverge for α smaller than approximately 0.5. Numerical results are shown for the diffusion equation and the Navier-Stokes equations on regular and irregular grids. The study suggests that α = 1 and 4/3 are suitable values for robust and efficient computations, and α = 4 / 3 is recommended for the diffusion equation, which achieves higher-order accuracy on regular quadrilateral grids. Finally, a Jacobian-Free Newton-Krylov solver with the implicit solver (a low-order Jacobian approximately inverted by a multi-color Gauss-Seidel relaxation scheme) used as a variable preconditioner is recommended for practical computations, which provides robust and efficient convergence for a wide range of α.

High-intensity Interval Training Frequency: Cardiometabolic Effects and Quality of Life.

PubMed

Stavrinou, Pinelopi S; Bogdanis, Gregory C; Giannaki, Christoforos D; Terzis, Gerasimos; Hadjicharalambous, Marios

2018-02-01

The effects of high intensity interval training (HIIT) frequency on cardiometabolic health and quality of life were examined in 35 healthy inactive adults (age: 31.7±2.6 yrs, VO 2 peak: 32.7±7.4 ml·: kg -1 ·: min -1 ). Participants were randomly assigned to a control (CON) and two training groups, which performed 10×60-s cycling at ~83% of peak power, two (HIIT-2) or three times per week (HIIT-3) for eight weeks. Compared with CON, both training regimes resulted in similar improvements in VO 2 peak (HIIT-2: 10.8%, p=0.048, HIIT-3: 13.6%, p=0.017), waist circumference (HIIT-2: -1.4 cm, p=0.048, HIIT-3: -2.4 cm, p=0.028), thigh cross-sectional area (HIIT-2: 11.4 cm 2 , p=0.001, HIIT-3: 9.3 cm 2 , p=0.001) and the physical health component of quality of life (HIIT-2: 8.4, p=0.001, HIIT-3: 12.2, p=0.001). However, HIIT-3 conferred additional health-related benefits by reducing total body and trunk fat percentage (p<0.05, compared with CON), total cholesterol and low-density lipoprotein-cholesterol (p<0.02, compared with CON) and by improving the mental component of quality of life (p=0.045, compared with CON). In conclusion, performing HIIT only twice per week is effective in promoting cardiometabolic health-related adaptations and quality of life in inactive adults. However, higher HIIT frequency is required for an effect on fat deposits, cholesterol and mental component of well-being. © Georg Thieme Verlag KG Stuttgart · New York.

Real-Time, High-Frequency QRS Electrocardiograph

NASA Technical Reports Server (NTRS)

Schlegel, Todd T.; DePalma, Jude L.; Moradi, Saeed

2003-01-01

An electronic system that performs real-time analysis of the low-amplitude, high-frequency, ordinarily invisible components of the QRS portion of an electrocardiographic signal in real time has been developed. Whereas the signals readily visible on a conventional electrocardiogram (ECG) have amplitudes of the order of a millivolt and are characterized by frequencies <100 Hz, the ordinarily invisible components have amplitudes in the microvolt range and are characterized by frequencies from about 150 to about 250 Hz. Deviations of these high-frequency components from a normal pattern can be indicative of myocardial ischemia or myocardial infarction

Basic characteristics of high-frequency Stark-effect modulation of CO2 lasers.

NASA Technical Reports Server (NTRS)

Claspy, P. C.; Pao, Y. H.

1971-01-01

The molecular Stark effect and its application to the modulation of infrared laser radiation have been investigated both theoretically and experimentally. Using a density matrix approach, a quantum mechanical description of the effect of a time-varying electric field on the absorption coefficient and refractive index of a molecular gas near an absorption line has been formulated. For modulation applications a quantity known as the ?modulation depth' is of prime importance. Theoretical expressions for the frequency dependence of the modulation depth show that the response to the frequency of a time-varying Stark field is separated into a nondispersive and a dispersive region, depending on whether the modulating frequency is less than or greater than the homogeneous absorption linewidth. Experimental results showing nondispersive modulation at frequencies to 30 MHz are presented. In addition it is shown that the response of modulation depth to Stark field amplitude is separated into linear and nonlinear regions, the field at which nonlinearities begin being determined by the absorption spectrum of the molecule being used.

Bactericidal effects of low-intensity extremely high frequency electromagnetic field: an overview with phenomenon, mechanisms, targets and consequences.

PubMed

Torgomyan, Heghine; Trchounian, Armen

2013-02-01

Low-intensity electromagnetic field (EMF) of extremely high frequencies is a widespread environmental factor. This field is used in telecommunication systems, therapeutic practices and food protection. Particularly, in medicine and food industries EMF is used for its bactericidal effects. The significant targets of cellular mechanisms for EMF effects at resonant frequencies in bacteria could be water (H(2)O), cell membrane and genome. The changes in H(2)O cluster structure and properties might be leading to increase of chemical activity or hydration of proteins and other cellular structures. These effects are likely to be specific and long-term. Moreover, cell membrane with its surface characteristics, substance transport and energy-conversing processes is also altered. Then, the genome is affected because the conformational changes in DNA and the transition of bacterial pro-phages from lysogenic to lytic state have been detected. The consequences for EMF interaction with bacteria are the changes in their sensitivity to different chemicals, including antibiotics. These effects are important to understand distinguishing role of bacteria in environment, leading to changed metabolic pathways in bacteria and their antibiotic resistance. This EMF may also affect the cell-to-cell interactions in bacterial populations, since bacteria might interact with each other through EMF of sub-extremely high frequency range.

Navy Applications of High-Frequency Acoustics

NASA Astrophysics Data System (ADS)

Cox, Henry

2004-11-01

Although the emphasis in underwater acoustics for the last few decades has been in low-frequency acoustics, motivated by long range detection of submarines, there has been a continuing use of high-frequency acoustics in traditional specialized applications such as bottom mapping, mine hunting, torpedo homing and under ice navigation. The attractive characteristics of high-frequency sonar, high spatial resolution, wide bandwidth, small size and relatively low cost must be balanced against the severe range limitation imposed by attenuation that increases approximately as frequency-squared. Many commercial applications of acoustics are ideally served by high-frequency active systems. The small size and low cost, coupled with the revolution in small powerful signal processing hardware has led to the consideration of more sophisticated systems. Driven by commercial applications, there are currently available several commercial-off-the-shelf products including acoustic modems for underwater communication, multi-beam fathometers, side scan sonars for bottom mapping, and even synthetic aperture side scan sonar. Much of the work in high frequency sonar today continues to be focused on specialized applications in which the application is emphasized over the underlying acoustics. Today's vision for the Navy of the future involves Autonomous Undersea Vehicles (AUVs) and off-board ASW sensors. High-frequency acoustics will play a central role in the fulfillment of this vision as a means of communication and as a sensor. The acoustic communication problems for moving AUVs and deep sensors are discussed. Explicit relationships are derived between the communication theoretic description of channel parameters in terms of time and Doppler spreads and ocean acoustic parameters, group velocities, phase velocities and horizontal wavenumbers. Finally the application of synthetic aperture sonar to the mine hunting problems is described.

The enhanced effects of antibiotics irradiated of extremely high frequency electromagnetic field on Escherichia coli growth properties.

PubMed

Torgomyan, Heghine; Trchounian, Armen

2015-01-01

The effects of extremely high frequency electromagnetic irradiation and antibiotics on Escherichia coli can create new opportunities for applications in different areas—medicine, agriculture, and food industry. Previously was shown that irradiated bacterial sensitivity against antibiotics was changed. In this work, it was presented the results that irradiation of antibiotics and then adding into growth medium was more effective compared with non-irradiated antibiotics bactericidal action. The selected antibiotics (tetracycline, kanamycin, chloramphenicol, and ceftriaxone) were from different groups. Antibiotics irradiation was performed with low intensity 53 GHz frequency during 1 h. The E. coli growth properties—lag-phase duration and specific growth rate—were markedly changed. Enhanced bacterial sensitivity to irradiated antibiotics is similar to the effects of antibiotics of higher concentrations.

New high-frequency weldable polyolefin films.

PubMed

Kelch, R

2000-05-01

There is an increasing desire for plastic films that can be sealed using high-frequency energy. Tests on new high-frequency polyolefin film structures are reported, which compare them with the characteristics and performance of poly(vinyl chloride), ethylene-vinyl acetate and thermoplastic polyurethane films.

Gender identification from high-pass filtered vowel segments: the use of high-frequency energy.

PubMed

Donai, Jeremy J; Lass, Norman J

2015-10-01

The purpose of this study was to examine the use of high-frequency information for making gender identity judgments from high-pass filtered vowel segments produced by adult speakers. Specifically, the effect of removing lower-frequency spectral detail (i.e., F3 and below) from vowel segments via high-pass filtering was evaluated. Thirty listeners (ages 18-35) with normal hearing participated in the experiment. A within-subjects design was used to measure gender identification for six 250-ms vowel segments (/æ/, /ɪ /, /ɝ/, /ʌ/, /ɔ/, and /u/), produced by ten male and ten female speakers. The results of this experiment demonstrated that despite the removal of low-frequency spectral detail, the listeners were accurate in identifying speaker gender from the vowel segments, and did so with performance significantly above chance. The removal of low-frequency spectral detail reduced gender identification by approximately 16 % relative to unfiltered vowel segments. Classification results using linear discriminant function analyses followed the perceptual data, using spectral and temporal representations derived from the high-pass filtered segments. Cumulatively, these findings indicate that normal-hearing listeners are able to make accurate perceptual judgments regarding speaker gender from vowel segments with low-frequency spectral detail removed via high-pass filtering. Therefore, it is reasonable to suggest the presence of perceptual cues related to gender identity in the high-frequency region of naturally produced vowel signals. Implications of these findings and possible mechanisms for performing the gender identification task from high-pass filtered stimuli are discussed.

The Origin of High-Frequency Hearing in Whales.

PubMed

Churchill, Morgan; Martinez-Caceres, Manuel; de Muizon, Christian; Mnieckowski, Jessica; Geisler, Jonathan H

2016-08-22

Odontocetes (toothed whales) rely upon echoes of their own vocalizations to navigate and find prey underwater [1]. This sensory adaptation, known as echolocation, operates most effectively when using high frequencies, and odontocetes are rivaled only by bats in their ability to perceive ultrasonic sound greater than 100 kHz [2]. Although features indicative of ultrasonic hearing are present in the oldest known odontocetes [3], the significance of this finding is limited by the methods employed and taxa sampled. In this report, we describe a new xenorophid whale (Echovenator sandersi, gen. et sp. nov.) from the Oligocene of South Carolina that, as a member of the most basal clade of odontocetes, sheds considerable light on the evolution of ultrasonic hearing. By placing high-resolution CT data from Echovenator sandersi, 2 hippos, and 23 fossil and extant whales in a phylogenetic context, we conclude that ultrasonic hearing, albeit in a less specialized form, evolved at the base of the odontocete radiation. Contrary to the hypothesis that odontocetes evolved from low-frequency specialists [4], we find evidence that stem cetaceans, the archaeocetes, were more sensitive to high-frequency sound than their terrestrial ancestors. This indicates that selection for high-frequency hearing predates the emergence of Odontoceti and the evolution of echolocation. Copyright © 2016 Elsevier Ltd. All rights reserved.

Switching transients in high-frequency high-power converters using power MOSFET's

NASA Technical Reports Server (NTRS)

Sloane, T. H.; Owen, H. A., Jr.; Wilson, T. G.

1979-01-01

The use of MOSFETs in a high-frequency high-power dc-to-dc converter is investigated. Consideration is given to the phenomena associated with the paralleling of MOSFETs and to the effect of stray circuit inductances on the converter circuit performance. Analytical relationships between various time constants during the turning-on and turning-off intervals are derived which provide estimates of plateau and peak levels during these intervals.

Effects of Multimedia Instruction on L2 Acquisition of High-Level, Low-Frequency English Vocabulary Words

ERIC Educational Resources Information Center

Cho, Euna

2017-01-01

The present study examined the effects of multimedia enhancement in video form in addition to textual information on L2 vocabulary instruction for high-level, low-frequency English words among Korean learners of English. Although input-based incidental learning of L2 vocabulary through extensive reading has been conventionally believed to be…

High-frequency ECG

NASA Technical Reports Server (NTRS)

Tragardh, Elin; Schlegel, Todd T.

2006-01-01

The standard ECG is by convention limited to 0.05-150 Hz, but higher frequencies are also present in the ECG signal. With high-resolution technology, it is possible to record and analyze these higher frequencies. The highest amplitudes of the high-frequency components are found within the QRS complex. In past years, the term "high frequency", "high fidelity", and "wideband electrocardiography" have been used by several investigators to refer to the process of recording ECGs with an extended bandwidth of up to 1000 Hz. Several investigators have tried to analyze HF-QRS with the hope that additional features seen in the QRS complex would provide information enhancing the diagnostic value of the ECG. The development of computerized ECG-recording devices that made it possible to record ECG signals with high resolution in both time and amplitude, as well as better possibilities to store and process the signals digitally, offered new methods for analysis. Different techniques to extract the HF-QRS have been described. Several bandwidths and filter types have been applied for the extraction as well as different signal-averaging techniques for noise reduction. There is no standard method for acquiring and quantifying HF-QRS. The physiological mechanisms underlying HF-QRS are still not fully understood. One theory is that HF-QRS are related to the conduction velocity and the fragmentation of the depolarization wave in the myocardium. In a three-dimensional model of the ventricles with a fractal conduction system it was shown that high numbers of splitting branches are associated with HF-QRS. In this experiment, it was also shown that the changes seen in HF-QRS in patients with myocardial ischemia might be due to the slowing of the conduction velocity in the region of ischemia. This mechanism has been tested by Watanabe et al by infusing sodium channel blockers into the left anterior descending artery in dogs. In their study, 60 unipolar ECGs were recorded from the entire

Real-time, high frequency QRS electrocardiograph

NASA Technical Reports Server (NTRS)

Schlegel, Todd T. (Inventor); DePalma, Jude L. (Inventor); Moradi, Saeed (Inventor)

2006-01-01

Real time cardiac electrical data are received from a patient, manipulated to determine various useful aspects of the ECG signal, and displayed in real time in a useful form on a computer screen or monitor. The monitor displays the high frequency data from the QRS complex in units of microvolts, juxtaposed with a display of conventional ECG data in units of millivolts or microvolts. The high frequency data are analyzed for their root mean square (RMS) voltage values and the discrete RMS values and related parameters are displayed in real time. The high frequency data from the QRS complex are analyzed with imbedded algorithms to determine the presence or absence of reduced amplitude zones, referred to herein as RAZs. RAZs are displayed as go, no-go signals on the computer monitor. The RMS and related values of the high frequency components are displayed as time varying signals, and the presence or absence of RAZs may be similarly displayed over time.

Harbour porpoises react to low levels of high frequency vessel noise

PubMed Central

Dyndo, Monika; Wiśniewska, Danuta Maria; Rojano-Doñate, Laia; Madsen, Peter Teglberg

2015-01-01

Cetaceans rely critically on sound for navigation, foraging and communication and are therefore potentially affected by increasing noise levels from human activities at sea. Shipping is the main contributor of anthropogenic noise underwater, but studies of shipping noise effects have primarily considered baleen whales due to their good hearing at low frequencies, where ships produce most noise power. Conversely, the possible effects of vessel noise on small toothed whales have been largely ignored due to their poor low-frequency hearing. Prompted by recent findings of energy at medium- to high-frequencies in vessel noise, we conducted an exposure study where the behaviour of four porpoises (Phocoena phocoena) in a net-pen was logged while they were exposed to 133 vessel passages. Using a multivariate generalised linear mixed-effects model, we show that low levels of high frequency components in vessel noise elicit strong, stereotyped behavioural responses in porpoises. Such low levels will routinely be experienced by porpoises in the wild at ranges of more than 1000 meters from vessels, suggesting that vessel noise is a, so far, largely overlooked, but substantial source of disturbance in shallow water areas with high densities of both porpoises and vessels. PMID:26095689

High precision pulsar timing and spin frequency second derivatives

NASA Astrophysics Data System (ADS)

Liu, X. J.; Bassa, C. G.; Stappers, B. W.

2018-05-01

We investigate the impact of intrinsic, kinematic and gravitational effects on high precision pulsar timing. We present an analytical derivation and a numerical computation of the impact of these effects on the first and second derivative of the pulsar spin frequency. In addition, in the presence of white noise, we derive an expression to determine the expected measurement uncertainty of a second derivative of the spin frequency for a given timing precision, observing cadence and timing baseline and find that it strongly depends on the latter (∝t-7/2). We show that for pulsars with significant proper motion, the spin frequency second derivative is dominated by a term dependent on the radial velocity of the pulsar. Considering the data sets from three Pulsar Timing Arrays, we find that for PSR J0437-4715 a detectable spin frequency second derivative will be present if the absolute value of the radial velocity exceeds 33 km s-1. Similarly, at the current timing precision and cadence, continued timing observations of PSR J1909-3744 for about another eleven years, will allow the measurement of its frequency second derivative and determine the radial velocity with an accuracy better than 14 km s-1. With the ever increasing timing precision and observing baselines, the impact of the, largely unknown, radial velocities of pulsars on high precision pulsar timing can not be neglected.

Combinational light emitting diode-high frequency focused ultrasound treatment for HeLa cell.

PubMed

Choe, Se-Woon; Park, Kitae; Park, Chulwoo; Ryu, Jaemyung; Choi, Hojong

2017-12-01

Light sources such as laser and light emitting diode or ultrasound devices have been widely used for cancer therapy and regenerative medicines, since they are more cost-effective and less harmful than radiation therapy, chemotherapy or magnetic treatment. Compared to laser and low intensity ultrasound techniques, light emitting diode and high frequency focused ultrasound shows enhanced therapeutic effects, especially for small tumors. We propose combinational light emitting diode-high frequency focused ultrasound treatment for human cervical cancer HeLa cells. Individual red, green, and blue light emitting diode light only, high frequency focused ultrasound only, or light emitting diode light combined with high frequency focused ultrasound treatments were applied in order to characterize the responses of HeLa cells. Cell density exposed by blue light emitting diode light combined with high frequency focused ultrasound (2.19 ± 0.58%) was much lower than that of cells exposed by red and green light emitting diode lights (81.71 ± 9.92% and 61.81 ± 4.09%), blue light emitting diode light (11.19 ± 2.51%) or high frequency focused ultrasound only (9.72 ± 1.04%). We believe that the proposed combinational blue light emitting diode-high frequency focused ultrasound treatment could have therapeutic benefits to alleviate cancer cell proliferation.

Recognition memory and awareness: A high-frequency advantage in the accuracy of knowing.

PubMed

Gregg, Vernon H; Gardiner, John M; Karayianni, Irene; Konstantinou, Ira

2006-04-01

The well-established advantage of low-frequency words over high-frequency words in recognition memory has been found to occur in remembering and not knowing. Two experiments employed remember and know judgements, and divided attention to investigate the possibility of an effect of word frequency on know responses given appropriate study conditions. With undivided attention at study, the usual low-frequency advantage in the accuracy of remember responses, but no effect on know responses, was obtained. Under a demanding divided attention task at encoding, a high-frequency advantage in the accuracy of know responses was obtained. The results are discussed in relation to theories of knowing, particularly those incorporating perceptual and conceptual fluency.

Acoustic Treatment Design Scaling Methods. Volume 2; Advanced Treatment Impedance Models for High Frequency Ranges

NASA Technical Reports Server (NTRS)

Kraft, R. E.; Yu, J.; Kwan, H. W.

1999-01-01

The primary purpose of this study is to develop improved models for the acoustic impedance of treatment panels at high frequencies, for application to subscale treatment designs. Effects that cause significant deviation of the impedance from simple geometric scaling are examined in detail, an improved high-frequency impedance model is developed, and the improved model is correlated with high-frequency impedance measurements. Only single-degree-of-freedom honeycomb sandwich resonator panels with either perforated sheet or "linear" wiremesh faceplates are considered. The objective is to understand those effects that cause the simple single-degree-of- freedom resonator panels to deviate at the higher-scaled frequency from the impedance that would be obtained at the corresponding full-scale frequency. This will allow the subscale panel to be designed to achieve a specified impedance spectrum over at least a limited range of frequencies. An advanced impedance prediction model has been developed that accounts for some of the known effects at high frequency that have previously been ignored as a small source of error for full-scale frequency ranges.

Evidence for Separate Contributions of High and Low Spatial Frequencies during Visual Word Recognition.

PubMed

Winsler, Kurt; Holcomb, Phillip J; Midgley, Katherine J; Grainger, Jonathan

2017-01-01

Previous studies have shown that different spatial frequency information processing streams interact during the recognition of visual stimuli. However, it is a matter of debate as to the contributions of high and low spatial frequency (HSF and LSF) information for visual word recognition. This study examined the role of different spatial frequencies in visual word recognition using event-related potential (ERP) masked priming. EEG was recorded from 32 scalp sites in 30 English-speaking adults in a go/no-go semantic categorization task. Stimuli were white characters on a neutral gray background. Targets were uppercase five letter words preceded by a forward-mask (#######) and a 50 ms lowercase prime. Primes were either the same word (repeated) or a different word (un-repeated) than the subsequent target and either contained only high, only low, or full spatial frequency information. Additionally within each condition, half of the prime-target pairs were high lexical frequency, and half were low. In the full spatial frequency condition, typical ERP masked priming effects were found with an attenuated N250 (sub-lexical) and N400 (lexical-semantic) for repeated compared to un-repeated primes. For HSF primes there was a weaker N250 effect which interacted with lexical frequency, a significant reversal of the effect around 300 ms, and an N400-like effect for only high lexical frequency word pairs. LSF primes did not produce any of the classic ERP repetition priming effects, however they did elicit a distinct early effect around 200 ms in the opposite direction of typical repetition effects. HSF information accounted for many of the masked repetition priming ERP effects and therefore suggests that HSFs are more crucial for word recognition. However, LSFs did produce their own pattern of priming effects indicating that larger scale information may still play a role in word recognition.

Extremely high frequency electromagnetic radiation enforces bacterial effects of inhibitors and antibiotics.

PubMed

Tadevosyan, Hasmik; Kalantaryan, Vitaly; Trchounian, Armen

2008-01-01

The coherent electromagnetic radiation (EMR) of the frequency of 51.8 and 53 GHz with low intensity (the power flux density of 0.06 mW/cm(2)) affected the growth of Escherichia coli K12(lambda) under fermentation conditions: the lowering of the growth specific rate was considerably (approximately 2-fold) increased with exposure duration of 30-60 min; a significant decrease in the number of viable cells was also shown. Moreover, the enforced effects of the N,N'-dicyclohexylcarbodiimide (DCCD), inhibitor of H(+)-transporting F(0)F(1)-ATPase, on energy-dependent H(+) efflux by whole cells and of antibiotics like tetracycline and chloramphenicol on the following bacterial growth and survival were also determined after radiation. In addition, the lowering in DCCD-inhibited ATPase activity of membrane vesicles from exposed cells was defined. The results confirmed the input of membranous changes in bacterial action of low intensity extremely high frequency EMR, when the F(0)F(1)-ATPase is probably playing a key role. The radiation of bacteria might lead to changed metabolic pathways and to antibiotic resistance. It may also give bacteria with a specific role in biosphere.

Reduced impedance and superconductivity of SnAgCu solder alloy at high frequency

NASA Astrophysics Data System (ADS)

Yao, Wei; Basaran, Cemal

2012-10-01

Skin effect of lead-free solder joints is investigated over a wide frequency band. Contrary to common believe that `effective impedance of solder alloys increases with frequency', resistance tends to saturate when frequency reaches a critical value, 10 MHz for SAC solder alloys. Negative surface impedance growth rate is observed when employs square waveform AC current loading at high current density. Further increased frequency causes a dramatic reduction of effective resistance. At 11 MHz with current density of 106 A/cm2, effective resistance of solder alloy drops to near zero value.

Monitoring method and apparatus using high-frequency carrier

DOEpatents

Haynes, Howard D.

1996-01-01

A method and apparatus for monitoring an electrical-motor-driven device by injecting a high frequency carrier signal onto the power line current. The method is accomplished by injecting a high frequency carrier signal onto an AC power line current. The AC power line current supplies the electrical-motor-driven device with electrical energy. As a result, electrical and mechanical characteristics of the electrical-motor-driven device modulate the high frequency carrier signal and the AC power line current. The high frequency carrier signal is then monitored, conditioned and demodulated. Finally, the modulated high frequency carrier signal is analyzed to ascertain the operating condition of the electrical-motor-driven device.

Millimeter waves or extremely high frequency electromagnetic fields in the environment: what are their effects on bacteria?

PubMed

Soghomonyan, Diana; Trchounian, Karen; Trchounian, Armen

2016-06-01

Millimeter waves (MMW) or electromagnetic fields of extremely high frequencies at low intensity is a new environmental factor, the level of which is increased as technology advance. It is of interest that bacteria and other cells might communicate with each other by electromagnetic field of sub-extremely high frequency range. These MMW affected Escherichia coli and many other bacteria, mainly depressing their growth and changing properties and activity. These effects were non-thermal and depended on different factors. The significant cellular targets for MMW effects could be water, cell plasma membrane, and genome. The model for the MMW interaction with bacteria is suggested; a role of the membrane-associated proton FOF1-ATPase, key enzyme of bioenergetic relevance, is proposed. The consequences of MMW interaction with bacteria are the changes in their sensitivity to different biologically active chemicals, including antibiotics. Novel data on MMW effects on bacteria and their sensitivity to different antibiotics are presented and discussed; the combined action of MMW and antibiotics resulted with more strong effects. These effects are of significance for understanding changed metabolic pathways and distinguish role of bacteria in environment; they might be leading to antibiotic resistance in bacteria. The effects might have applications in the development of technique, therapeutic practices, and food protection technology.

Effects of high-frequency activity on latent heat flux of MJO

NASA Astrophysics Data System (ADS)

Gao, Yingxia; Hsu, Pang-Chi; Li, Tim

2018-04-01

The effect of high-frequency (HF) variability on latent heat flux (LHF) associated with the Madden-Julian Oscillation (MJO) during the boreal winter is investigated through diagnosis using two reanalysis datasets and numerical experiments of an atmospheric general circulation model (AGCM). The diagnostic results show that the HF activities exert an impact on the variability of MJO LHF mainly through their interactions with the longer than 90-day low-frequency background state (LFBS). The contribution of intraseasonal LHF induced by the interactions between LFBS and HF activities accounts for more than 20% of the total intraseasonal LHF over active MJO regions. The intraseasonal LHF induced by the LFBS-HF interaction is in phase with the MJO convection, while the total intraseasonal LHF appears at and to the west of the MJO convection center. This suggests that the intraseasonal LHF via the feedback of HF activity interacting with LFBS is conducive to the maintenance and eastward propagation of MJO convection. To confirm the role of HF disturbances in MJO convection activity, we carry out a series of experiments using the AGCM of ECHAM4, which captures well the general features of MJO. We select a number of MJO cases with enhanced convective signals and significant eastward propagation from a 30-year climatological simulation. Once the HF components of surface wind and moisture fields in LHF are excluded in model integration for each MJO case, most of the simulated MJO convection shows weakened activity and a slower propagation speed compared to the simulations containing all time-scale components. The outputs of these sensitivity experiments support the diagnostic results that HF activities contribute to the maintenance and propagation of MJO convection through the intraseasonal LHF induced by the scale interaction of HF activities with lower frequency variability.

In vivo photoacoustics and high frequency ultrasound imaging of mechanical high intensity focused ultrasound (HIFU) ablation.

PubMed

Daoudi, Khalid; Hoogenboom, Martijn; den Brok, Martijn; Eikelenboom, Dylan; Adema, Gosse J; Fütterer, Jürgen J; de Korte, Chris L

2017-04-01

The thermal effect of high intensity focused ultrasound (HIFU) has been clinically exploited over a decade, while the mechanical HIFU is still largely confined to laboratory investigations. This is in part due to the lack of adequate imaging techniques to better understand the in-vivo pathological and immunological effects caused by the mechanical treatment. In this work, we explore the use of high frequency ultrasound (US) and photoacoustics (PA) as a potential tool to evaluate the effect of mechanical ablation in-vivo , e.g. boiling histotripsy. Two mice bearing a neuroblastoma tumor in the right leg were ablated using an MRI-HIFU system conceived for small animals and monitored using MRI thermometry. High frequency US and PA imaging were performed before and after the HIFU treatment. Afterwards, the tumor was resected for further assessment and evaluation of the ablated region using histopathology. High frequency US imaging revealed the presence of liquefied regions in the treated area together with fragmentized tissue which appeared with different reflecting proprieties compared to the surrounding tissue. Photoacoustic imaging on the other hand revealed the presence of deoxygenated blood within the tumor after the ablation due to the destruction of blood vessel network while color Doppler imaging confirmed the blood vessel network destruction within the tumor. The treated area and the presence of red blood cells detected by photoacoustics were further confirmed by the histopathology. This feasibility study demonstrates the potential of high frequency US and PA approach for assessing in-vivo the effect of mechanical HIFU tumor ablation.

In vivo photoacoustics and high frequency ultrasound imaging of mechanical high intensity focused ultrasound (HIFU) ablation

PubMed Central

Daoudi, Khalid; Hoogenboom, Martijn; den Brok, Martijn; Eikelenboom, Dylan; Adema, Gosse J.; Fütterer, Jürgen J.; de Korte, Chris L.

2017-01-01

The thermal effect of high intensity focused ultrasound (HIFU) has been clinically exploited over a decade, while the mechanical HIFU is still largely confined to laboratory investigations. This is in part due to the lack of adequate imaging techniques to better understand the in-vivo pathological and immunological effects caused by the mechanical treatment. In this work, we explore the use of high frequency ultrasound (US) and photoacoustics (PA) as a potential tool to evaluate the effect of mechanical ablation in-vivo, e.g. boiling histotripsy. Two mice bearing a neuroblastoma tumor in the right leg were ablated using an MRI-HIFU system conceived for small animals and monitored using MRI thermometry. High frequency US and PA imaging were performed before and after the HIFU treatment. Afterwards, the tumor was resected for further assessment and evaluation of the ablated region using histopathology. High frequency US imaging revealed the presence of liquefied regions in the treated area together with fragmentized tissue which appeared with different reflecting proprieties compared to the surrounding tissue. Photoacoustic imaging on the other hand revealed the presence of deoxygenated blood within the tumor after the ablation due to the destruction of blood vessel network while color Doppler imaging confirmed the blood vessel network destruction within the tumor. The treated area and the presence of red blood cells detected by photoacoustics were further confirmed by the histopathology. This feasibility study demonstrates the potential of high frequency US and PA approach for assessing in-vivo the effect of mechanical HIFU tumor ablation. PMID:28736668

High-Resolution Audio with Inaudible High-Frequency Components Induces a Relaxed Attentional State without Conscious Awareness.

PubMed

Kuribayashi, Ryuma; Nittono, Hiroshi

2017-01-01

High-resolution audio has a higher sampling frequency and a greater bit depth than conventional low-resolution audio such as compact disks. The higher sampling frequency enables inaudible sound components (above 20 kHz) that are cut off in low-resolution audio to be reproduced. Previous studies of high-resolution audio have mainly focused on the effect of such high-frequency components. It is known that alpha-band power in a human electroencephalogram (EEG) is larger when the inaudible high-frequency components are present than when they are absent. Traditionally, alpha-band EEG activity has been associated with arousal level. However, no previous studies have explored whether sound sources with high-frequency components affect the arousal level of listeners. The present study examined this possibility by having 22 participants listen to two types of a 400-s musical excerpt of French Suite No. 5 by J. S. Bach (on cembalo, 24-bit quantization, 192 kHz A/D sampling), with or without inaudible high-frequency components, while performing a visual vigilance task. High-alpha (10.5-13 Hz) and low-beta (13-20 Hz) EEG powers were larger for the excerpt with high-frequency components than for the excerpt without them. Reaction times and error rates did not change during the task and were not different between the excerpts. The amplitude of the P3 component elicited by target stimuli in the vigilance task increased in the second half of the listening period for the excerpt with high-frequency components, whereas no such P3 amplitude change was observed for the other excerpt without them. The participants did not distinguish between these excerpts in terms of sound quality. Only a subjective rating of inactive pleasantness after listening was higher for the excerpt with high-frequency components than for the other excerpt. The present study shows that high-resolution audio that retains high-frequency components has an advantage over similar and indistinguishable digital sound

High frequency ultrasound: a new frontier for ultrasound.

PubMed

Shung, K; Cannata, Jonathan; Qifa Zhou, Member; Lee, Jungwoo

2009-01-01

High frequency ultrasonic imaging is considered by many to be the next frontier in ultrasonic imaging because higher frequencies yield much improved spatial resolution by sacrificing the depth of penetration. It has many clinical applications including visualizing blood vessel wall, anterior segments of the eye and skin. Another application is small animal imaging. Ultrasound is especially attractive in imaging the heart of a small animal like mouse which has a size in the mm range and a heart beat rate faster than 600 BPM. A majority of current commercial high frequency scanners often termed "ultrasonic backscatter microscope or UBM" acquire images by scanning single element transducers at frequencies between 50 to 80 MHz with a frame rate lower than 40 frames/s, making them less suitable for this application. High frequency linear arrays and linear array based ultrasonic imaging systems at frequencies higher than 30 MHz are being developed. The engineering of such arrays and development of high frequency imaging systems has been proven to be highly challenging. High frequency ultrasound may find other significant biomedical applications. The development of acoustic tweezers for manipulating microparticles is such an example.

Robust Optimization Design Algorithm for High-Frequency TWTs

NASA Technical Reports Server (NTRS)

Wilson, Jeffrey D.; Chevalier, Christine T.

2010-01-01

Traveling-wave tubes (TWTs), such as the Ka-band (26-GHz) model recently developed for the Lunar Reconnaissance Orbiter, are essential as communication amplifiers in spacecraft for virtually all near- and deep-space missions. This innovation is a computational design algorithm that, for the first time, optimizes the efficiency and output power of a TWT while taking into account the effects of dimensional tolerance variations. Because they are primary power consumers and power generation is very expensive in space, much effort has been exerted over the last 30 years to increase the power efficiency of TWTs. However, at frequencies higher than about 60 GHz, efficiencies of TWTs are still quite low. A major reason is that at higher frequencies, dimensional tolerance variations from conventional micromachining techniques become relatively large with respect to the circuit dimensions. When this is the case, conventional design- optimization procedures, which ignore dimensional variations, provide inaccurate designs for which the actual amplifier performance substantially under-performs that of the design. Thus, this new, robust TWT optimization design algorithm was created to take account of and ameliorate the deleterious effects of dimensional variations and to increase efficiency, power, and yield of high-frequency TWTs. This design algorithm can help extend the use of TWTs into the terahertz frequency regime of 300-3000 GHz. Currently, these frequencies are under-utilized because of the lack of efficient amplifiers, thus this regime is known as the "terahertz gap." The development of an efficient terahertz TWT amplifier could enable breakthrough applications in space science molecular spectroscopy, remote sensing, nondestructive testing, high-resolution "through-the-wall" imaging, biomedical imaging, and detection of explosives and toxic biochemical agents.

Antecedent Frequency Effects on Anaphoric Pronoun Resolution: Evidence from Spanish

ERIC Educational Resources Information Center

Egusquiza, Nerea; Navarrete, Eduardo; Zawiszewski, Adam

2016-01-01

High-frequency words are usually understood and produced faster than low-frequency words. Although the effect of word frequency is a reliable phenomenon in many domains of language processing, it remains unclear whether and how frequency affects pronominal anaphoric resolution. We evaluated this issue by means of two self-paced reading…

GPM Data Products, Their Availability, and Production Status

NASA Technical Reports Server (NTRS)

Stocker, Erich Franz; Kelley, Owen; Kwiatkowski, John; Ji, Yimin

2014-01-01

On February 28, 2014, Japan Standard Time, the Global Precipitation Measurement (GPM) mission was launched in a picture-perfect launch activity. On March 4, 2014, the GPM Microwave Imager (GMI) was put into science observation mode. The Dual-Frequency Radar (DPR) was put in science observation mode on March 8, 2014. The Precipitation Processing System (PPS) produced products immediately upon receiving the data. Both regular science products and Near-realtime (NRT) products were produced. These were made immediately available to a group of early adopters. In mid-June 2014, GMI level-1 brightness temperature products were made publicly available. In mid-July 2014, GMI and partner-radiometer precipitation retrievals were made public. GMI public availability was several months ahead of the planned release. The DPR products became publicly available on the planned release date of September 2, 2014. Data continues to be available to any user desiring it.

High frequency, high power capacitor development

NASA Astrophysics Data System (ADS)

White, C. W.; Hoffman, P. S.

1983-03-01

A program to develop a special high energy density, high power transfer capacitor to operate at frequency of 40 kHz, 600 V rms at 125 A rms plus 600 V dc bias for space operation. The program included material evaluation and selection, a capacitor design was prepared, a thermal analysis performed on the design. Fifty capacitors were manufactured for testing at 10 kHz and 40 kHz for 50 hours at Industrial Electric Heating Co. of Columbus, Ohio. The vacuum endurance test used on environmental chamber and temperature plate furnished by Maxwell. The capacitors were energized with a special power conditioning apparatus developed by Industrial Electric Heating Co. Temperature conditions of the capacitors were monitored by IEHCo test equipment. Successful completion of the vacuum endurance test series confirmed achievement of the main goal of producing a capacitor or reliable operation at high frequency in an environment normally not hospitable to electrical and electronic components. The capacitor developed compared to a typical commercial capacitor at the 40 kHz level represents a decrease in size and weight by a factor of seven.

High frequency, high power capacitor development

NASA Technical Reports Server (NTRS)

White, C. W.; Hoffman, P. S.

1983-01-01

A program to develop a special high energy density, high power transfer capacitor to operate at frequency of 40 kHz, 600 V rms at 125 A rms plus 600 V dc bias for space operation. The program included material evaluation and selection, a capacitor design was prepared, a thermal analysis performed on the design. Fifty capacitors were manufactured for testing at 10 kHz and 40 kHz for 50 hours at Industrial Electric Heating Co. of Columbus, Ohio. The vacuum endurance test used on environmental chamber and temperature plate furnished by Maxwell. The capacitors were energized with a special power conditioning apparatus developed by Industrial Electric Heating Co. Temperature conditions of the capacitors were monitored by IEHCo test equipment. Successful completion of the vacuum endurance test series confirmed achievement of the main goal of producing a capacitor or reliable operation at high frequency in an environment normally not hospitable to electrical and electronic components. The capacitor developed compared to a typical commercial capacitor at the 40 kHz level represents a decrease in size and weight by a factor of seven.

Temperature dependence of frequency response characteristics in organic field-effect transistors

NASA Astrophysics Data System (ADS)

Lu, Xubing; Minari, Takeo; Liu, Chuan; Kumatani, Akichika; Liu, J.-M.; Tsukagoshi, Kazuhito

2012-04-01

The frequency response characteristics of semiconductor devices play an essential role in the high-speed operation of electronic devices. We investigated the temperature dependence of dynamic characteristics in pentacene-based organic field-effect transistors and metal-insulator-semiconductor capacitors. As the temperature decreased, the capacitance-voltage characteristics showed large frequency dispersion and a negative shift in the flat-band voltage at high frequencies. The cutoff frequency shows Arrhenius-type temperature dependence with different activation energy values for various gate voltages. These phenomena demonstrate the effects of charge trapping on the frequency response characteristics, since decreased mobility prevents a fast charge response for alternating current signals at low temperatures.

Monitoring method and apparatus using high-frequency carrier

DOEpatents

Haynes, H.D.

1996-04-30

A method and apparatus for monitoring an electrical-motor-driven device by injecting a high frequency carrier signal onto the power line current. The method is accomplished by injecting a high frequency carrier signal onto an AC power line current. The AC power line current supplies the electrical-motor-driven device with electrical energy. As a result, electrical and mechanical characteristics of the electrical-motor-driven device modulate the high frequency carrier signal and the AC power line current. The high frequency carrier signal is then monitored, conditioned and demodulated. Finally, the modulated high frequency carrier signal is analyzed to ascertain the operating condition of the electrical-motor-driven device. 6 figs.

Electromagnetic inhibition of high frequency thermal bonding machine

NASA Astrophysics Data System (ADS)

He, Hong; Zhang, Qing-qing; Li, Hang; Zhang, Da-jian; Hou, Ming-feng; Zhu, Xian-wei

2011-12-01

The traditional high frequency thermal bonding machine had serious radiation problems at dominant frequency, two times frequency and three times frequency. Combining with its working principle, the problems of electromagnetic compatibility were studied, three following measures were adopted: 1.At the head part of the high frequency thermal bonding machine, resonant circuit attenuator was designed. The notch groove and reaction field can make the radiation being undermined or absorbed; 2.The electromagnetic radiation shielding was made for the high frequency copper power feeder; 3.Redesigned the high-frequency oscillator circuit to reduce the output of harmonic oscillator. The test results showed that these measures can make the output according with the national standard of electromagnetic compatibility (GB4824-2004-2A), the problems of electromagnetic radiation leakage can be solved, and good social, environmental and economic benefits would be brought.

Neural hijacking: action of high-frequency electrical stimulation on cortical circuits.

PubMed

Cheney, P D; Griffin, D M; Van Acker, G M

2013-10-01

Electrical stimulation of the brain was one of the first experimental methods applied to understanding brain organization and function and it continues as a highly useful method both in research and clinical applications. Intracortical microstimulation (ICMS) involves applying electrical stimuli through a microelectrode suitable for recording the action potentials of single neurons. ICMS can be categorized into single-pulse stimulation; high-frequency, short-duration stimulation; and high-frequency, long-duration stimulation. For clinical and experimental reasons, considerable interest focuses on the mechanism of neural activation by electrical stimuli. In this article, we discuss recent results suggesting that action potentials evoked in cortical neurons by high-frequency electrical stimulation do not sum with the natural, behaviorally related background activity; rather, high-frequency stimulation eliminates and replaces natural activity. We refer to this as neural hijacking. We propose that a major component of the mechanism underlying neural hijacking is excitation of axons by ICMS and elimination of natural spikes by antidromic collision with stimulus-driven spikes evoked at high frequency. Evidence also supports neural hijacking as an important mechanism underlying the action of deep brain stimulation in the subthalamic nucleus and its therapeutic effect in treating Parkinson's disease.

High Frequency High Spectral Resolution Focal Plane Arrays for AtLAST

NASA Astrophysics Data System (ADS)

Baryshev, Andrey

2018-01-01

Large collecting area single dish telescope such as ATLAST will be especially effective for medium (R 1000) and high (R 50000) spectral resolution observations. Large focal plane array is a natural solution to increase mapping speed. For medium resolution direct detectors with filter banks (KIDs) and or heterodyne technology can be employed. We will analyze performance limits of comparable KID and SIS focal plane array taking into account quantum limit and high background condition of terrestrial observing site. For large heterodyne focal plane arrays, a high current density AlN junctions open possibility of large instantaneous bandwidth >40%. This and possible multi frequency band FPSs presents a practical challenge for spatial sampling and scanning strategies. We will discuss phase array feeds as a possible solution, including a modular back-end system, which can be shared between KID and SIS based FPA. Finally we will discuss achievable sensitivities and pixel co unts for a high frequency (>500 GHz) FPAs and address main technical challenges: LO distribution, wire counts, bias line multiplexing, and monolithic vs. discrete mixer component integration.

Extended high-frequency thresholds in college students: effects of music player use and other recreational noise.

PubMed

Le Prell, Colleen G; Spankovich, Christopher; Lobariñas, Edward; Griffiths, Scott K

2013-09-01

Human hearing is sensitive to sounds from as low as 20 Hz to as high as 20,000 Hz in normal ears. However, clinical tests of human hearing rarely include extended high-frequency (EHF) threshold assessments, at frequencies extending beyond 8000 Hz. EHF thresholds have been suggested for use monitoring the earliest effects of noise on the inner ear, although the clinical usefulness of EHF threshold testing is not well established for this purpose. The primary objective of this study was to determine if EHF thresholds in healthy, young adult college students vary as a function of recreational noise exposure. A retrospective analysis of a laboratory database was conducted; all participants with both EHF threshold testing and noise history data were included. The potential for "preclinical" EHF deficits was assessed based on the measured thresholds, with the noise surveys used to estimate recreational noise exposure. EHF thresholds measured during participation in other ongoing studies were available from 87 participants (34 male and 53 female); all participants had hearing within normal clinical limits (≤25 HL) at conventional frequencies (0.25-8 kHz). EHF thresholds closely matched standard reference thresholds [ANSI S3.6 (1996) Annex C]. There were statistically reliable threshold differences in participants who used music players, with 3-6 dB worse thresholds at the highest test frequencies (10-16 kHz) in participants who reported long-term use of music player devices (>5 yr), or higher listening levels during music player use. It should be possible to detect small changes in high-frequency hearing for patients or participants who undergo repeated testing at periodic intervals. However, the increased population-level variability in thresholds at the highest frequencies will make it difficult to identify the presence of small but potentially important deficits in otherwise normal-hearing individuals who do not have previously established baseline data. American

GPM Mission Gridded Text Products Providing Surface Precipitation Retrievals

NASA Astrophysics Data System (ADS)

Stocker, Erich Franz; Kelley, Owen; Huffman, George; Kummerow, Christian

2015-04-01

In February 2015, the Global Precipitation Measurement (GPM) mission core satellite will complete its first year in space. The core satellite carries a conically scanning microwave imager called the GPM Microwave Imager (GMI), which also has 166 GHz and 183 GHz frequency channels. The GPM core satellite also carries a dual frequency radar (DPR) which operates at Ku frequency, similar to the Tropical Rainfall Measuring Mission (TRMM) Precipitation Radar), and a new Ka frequency. The precipitation processing system (PPS) is producing swath-based instantaneous precipitation retrievals from GMI, both radars including a dual-frequency product, and a combined GMI/DPR precipitation retrieval. These level 2 products are written in the HDF5 format and have many additional parameters beyond surface precipitation that are organized into appropriate groups. While these retrieval algorithms were developed prior to launch and are not optimal, these algorithms are producing very creditable retrievals. It is appropriate for a wide group of users to have access to the GPM retrievals. However, for reseachers requiring only surface precipitation, these L2 swath products can appear to be very intimidating and they certainly do contain many more variables than the average researcher needs. Some researchers desire only surface retrievals stored in a simple easily accessible format. In response, PPS has begun to produce gridded text based products that contain just the most widely used variables for each instrument (surface rainfall rate, fraction liquid, fraction convective) in a single line for each grid box that contains one or more observations. This paper will describe the gridded data products that are being produced and provide an overview of their content. Currently two types of gridded products are being produced: (1) surface precipitation retrievals from the core satellite instruments - GMI, DPR, and combined GMI/DPR (2) surface precipitation retrievals for the partner

Effect of Ultra High Frequency Mobile Phone Radiation on Human Health

PubMed Central

Moradi, Mosa; Naghdi, Nasrollah; Hemmati, Hamidreza; Asadi-Samani, Majid; Bahmani, Mahmoud

2016-01-01

Introduction Public and occupational exposure to electromagnetic fields due to the growing trend of electronic devices may cause adverse effects on human health. This paper describes the risk of mutation and sexual trauma and infertility in masculine sexual cell by mobile phone radiations. Methods In this study, we measured the emitted dose from a radiofrequency device, such as switching high voltage at different frequencies using a scintillation detector. The switching high voltage power supply (HVPS) was built for the Single Photon Emission Computed Tomography (SPECT) system. For radiation dosimetry, we used an ALNOR scintillator that can measure gamma radiation. The simulation was performed by MATLAB software, and data from the International Commission on Non-Ionizing Radiation Protection (ICNIRP) were used to verify the simulation. Results We investigated the risks that result from the waves, according to a report by International Commission on Non Ionizing Radiation Protection (ICNIRP), to every organ of the body is defined by the beam and electromagnetic radiation from this electronic device on people. The results showed that the maximum personal dose over a 15-min period working at the mentioned HVPS did not exceed 0.31 μSV/h (with an aluminum shield). So, according to other sources of radiation, continuous working time of the system should not be more than 10 hours. Finally, a characteristic curve for secure working with modules at different frequencies was reported. The RF input signal to the body for maximum penetration depth (δ) and electromagnetic energy absorption rate (SAR) of biological tissue were obtained for each tissue. Conclusion The results of this study and International Commission of Non Ionization Radiation Protection (ICNIRP) reports showed the people who spend more than 50 minutes a day using a cell phone could have early dementia or other thermal damage due to the burning of glucose in the brain. PMID:27382458

How High Frequency Trading Affects a Market Index

PubMed Central

Kenett, Dror Y.; Ben-Jacob, Eshel; Stanley, H. Eugene; gur-Gershgoren, Gitit

2013-01-01

The relationship between a market index and its constituent stocks is complicated. While an index is a weighted average of its constituent stocks, when the investigated time scale is one day or longer the index has been found to have a stronger effect on the stocks than vice versa. We explore how this interaction changes in short time scales using high frequency data. Using a correlation-based analysis approach, we find that in short time scales stocks have a stronger influence on the index. These findings have implications for high frequency trading and suggest that the price of an index should be published on shorter time scales, as close as possible to those of the actual transaction time scale. PMID:23817553

A high-performance Hg(+) trapped ion frequency standard

NASA Technical Reports Server (NTRS)

Prestage, J. D.; Tjoelker, R. L.; Dick, G. J.; Maleki, L.

1992-01-01

A high-performance frequency standard based on (199)Hg(+) ions confined in a hybrid radio frequency (RF)/dc linear ion trap is demonstrated. This trap permits storage of large numbers of ions with reduced susceptibility to the second-order Doppler effect caused by the RF confining fields. A 160-mHz-wide atomic resonance line for the 40.5-GHz clock transition is used to steer the output of a 5-mHz crystal oscillator to obtain a stability of 2 x 10(exp -15) for 24,000-second averaging times. Measurements with a 37-mHz line width for the Hg(+) clock transition demonstrate that the inherent stability for this frequency standard is better than 1 x 10(exp -15) at 10,000-second averaging times.

High-frequency hearing impairment assessed with cochlear microphonics.

PubMed

Zhang, Ming

2012-09-01

Cochlear microphonic (CM) measurements may potentially become a supplementary approach to otoacoustic emission (OAE) measurements for assessing low-frequency cochlear functions in the clinic. The objective of this study was to investigate the measurement of CMs in subjects with high-frequency hearing loss. Currently, CMs can be measured using electrocochleography (ECochG or ECoG) techniques. Both CMs and OAEs are cochlear responses, while auditory brainstem responses (ABRs) are not. However, there are inherent limitations associated with OAE measurements such as acoustic noise, which can conceal low-frequency OAEs measured in the clinic. However, CM measurements may not have these limitations. CMs were measured in human subjects using an ear canal electrode. The CMs were compared between the high-frequency hearing loss group and the normal-hearing control group. Distortion product OAEs (DPOAEs) and audiogram were also measured. The DPOAE and audiogram measurements indicate that the subjects were correctly selected for the two groups. Low-frequency CM waveforms (CMWs) can be measured using ear canal electrodes in high-frequency hearing loss subjects. The difference in amplitudes of CMWs between the high-frequency hearing loss group and the normal-hearing group is insignificant at low frequencies but significant at high frequencies.

GPM Microwave Imager Design, Predicted Performance and Status

NASA Technical Reports Server (NTRS)

Krimchansky, Sergey; Newell, David

2010-01-01

The Global Precipitation Measurement (GPM) Microwave Imager (GMI) Instrument is being developed by Ball Aerospace and Technology Corporation (BATC) for the GPM program at NASA Goddard. The Global Precipitation Measurement (GPM) mission is an international effort managed by the National Aeronautics and Space Administration (t.JASA) to improve climate, weather, and hydro-meteorological predictions through more accurate and more frequent precipitation measurements. The GPM Microwave Imager (GMI) will be used to make calibrated, radiometric measurements from space at multiple microwave frequencies and polarizations. GMI will be placed on the GPM Core Spacecraft together with the Dual-frequency Precipitation Radar (DPR). The DPR is two-frequency precipitation measurement radar, which will operate in the Ku-band and Ka-band of the microwave spectrum. The Core Spacecraft will make radiometric and radar measurements of clouds and precipitation and will be the central element of GPM's space segment. The data products from GPM will provide information concerning global precipitation on a frequent, near-global basis to meteorologists and scientists making weather forecasts and performing research on the global energy and water cycle, precipitation, hydrology, and related disciplines. In addition, radiometric measurements from GMI and radar measurements from the DPR will be used together to develop a retrieval transfer standard for the purpose of calibrating precipitation retrieval algorithms. This calibration standard will establish a reference against which other retrieval algorithms using only microwave radiometers (and without the benefit of the DPR) on other satellites in the GPM constellation will be compared.

High frequency reference electrode

DOEpatents

Kronberg, J.W.

1994-05-31

A high frequency reference electrode for electrochemical experiments comprises a mercury-calomel or silver-silver chloride reference electrode with a layer of platinum around it and a layer of a chemically and electrically resistant material such as TEFLON around the platinum covering all but a small ring or halo' at the tip of the reference electrode, adjacent to the active portion of the reference electrode. The voltage output of the platinum layer, which serves as a redox electrode, and that of the reference electrode are coupled by a capacitor or a set of capacitors and the coupled output transmitted to a standard laboratory potentiostat. The platinum may be applied by thermal decomposition to the surface of the reference electrode. The electrode provides superior high-frequency response over conventional electrodes. 4 figs.

High frequency reference electrode

DOEpatents

Kronberg, James W.

1994-01-01

A high frequency reference electrode for electrochemical experiments comprises a mercury-calomel or silver-silver chloride reference electrode with a layer of platinum around it and a layer of a chemically and electrically resistant material such as TEFLON around the platinum covering all but a small ring or "halo" at the tip of the reference electrode, adjacent to the active portion of the reference electrode. The voltage output of the platinum layer, which serves as a redox electrode, and that of the reference electrode are coupled by a capacitor or a set of capacitors and the coupled output transmitted to a standard laboratory potentiostat. The platinum may be applied by thermal decomposition to the surface of the reference electrode. The electrode provides superior high-frequency response over conventional electrodes.

Choosing Meteorological Input for the Global Modeling Initiative Assessment of High Speed Aircraft

NASA Technical Reports Server (NTRS)

Douglas, A. R.; Prather, M. P.; Hall, T. M.; Strahan, S. E.; Rasch, P. J.; Sparling, L. C.; Coy, L.; Rodriquez, J. M.

1998-01-01

The Global Modeling Initiative (GMI) science team is developing a three dimensional chemistry and transport model (CTM) to be used in assessment of the atmospheric effects of aviation. Requirements are that this model be documented, be validated against observations, use a realistic atmospheric circulation, and contain numerical transport and photochemical modules representing atmospheric processes. The model must also retain computational efficiency to be tractable to use for multiple scenarios and sensitivity studies. To meet these requirements, a facility model concept was developed in which the different components of the CTM are evaluated separately. The first use of the GMI model will be to evaluate the impact of the exhaust of supersonic aircraft on the stratosphere. The assessment calculations will depend strongly on the wind and temperature fields used by the CTM. Three meteorological data sets for the stratosphere are available to GMI: the National Center for Atmospheric Research Community Climate Model (CCM2), the Goddard Earth Observing System Data Assimilation System (GEOS DAS), and the Goddard Institute for Space Studies general circulation model (GISS). Objective criteria were established by the GMI team to identify the data set which provides the best representation of the stratosphere. Simulations of gases with simple chemical control were chosen to test various aspects of model transport. The three meteorological data sets were evaluated and graded based on their ability to simulate these aspects of stratospheric measurements. This paper describes the criteria used in grading the meteorological fields. The meteorological data set which has the highest score and therefore was selected for GMI is CCM2. This type of objective model evaluation establishes a physical basis for interpretation of differences between models and observations. Further, the method provides a quantitative basis for defining model errors, for discriminating between different

Development of Technologies for a High Efficiency, Very Low Emission, Diesel Engine for Light Trucks and Sport Utility Vehicles

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stang, John H.

2005-12-19

Cummins Inc., in partnership with the Department of Energy, has developed technology for a new highly efficient, very low emission, diesel engine for light trucks and sport utility vehicles. This work began in April 1997, and started with very aggressive goals for vehicles in the 5751 to 8500 pound GCW weight class. The primary program goals were as follows: (1) EMISSIONS -- NOx = 0.50 g/mi; PM = 0.05 g/mi; CO = 2.8 g/mi; and NMHC = 0.07 g/mi. California decided to issue new and even tougher LEV II light truck regulations late in 1999. EPA also issued its lowermore » Tier 2 regulations late in 2000. The net result was that the targets for this diesel engine project were lowered, and these goals were eventually modified by the publication of Federal Tier 2 emission standards early in 2000 to the following: NOx = 0.07 g/mi; and PM = 0.01 g/mi. (2) FUEL ECONOMY -- The fuel economy goal was 50 percent MPG improvement (combined city/highway) over the 1997 gasoline powered light truck or sport utility vehicle in the vehicle class for which this diesel engine is being designed to replace. The goal for fuel economy remained at 50 percent MPG improvement, even with the emissions goal revisions. (3) COOPERATIVE DEVELOPMENT -- Regular design reviews of the engine program will be conducted with a vehicle manufacturer to insure that the concepts and design specifics are commercially feasible. (DaimlerChrysler has provided Cummins with this design review input.) Cummins has essentially completed a demonstration of proof-of-principle for a diesel engine platform using advanced combustion and fuel system technologies. Cummins reported very early progress in this project, evidence that new diesel engine technology had been developed that demonstrated the feasibility of the above emissions goals. Emissions levels of NOx = 0.4 g/mi and PM = 0.06 g/mi were demonstrated for a 5250 lb. test weight vehicle with passive aftertreatment only. These results were achieved using the full

Development of Technologies for a High Efficiency, Very Low Emission, Diesel Engine for Light Trucks and Sport Utility Vehicles

DOE Office of Scientific and Technical Information (OSTI.GOV)

John H. Stang

2005-12-31

Cummins Inc., in partnership with the Department of Energy, has developed technology for a new highly efficient, very low emission, diesel engine for light trucks and sport utility vehicles. This work began in April 1997, and started with very aggressive goals for vehicles in the 5751 to 8500 pound GCW weight class. The primary program goals were as follows: (1) EMISSIONS--NO{sub x} = 0.50 g/mi; PM = 0.05 g/mi; CO = 2.8 g/mi; and NMHC = 0.07 g/mi. California decided to issue new and even tougher LEV II light truck regulations late in 1999. EPA also issued its lower Tiermore » 2 regulations late in 2000. The net result was that the targets for this diesel engine project were lowered, and these goals were eventually modified by the publication of Federal Tier 2 emission standards early in 2000 to the following: NO{sub x} = 0.07 g/mi; and PM = 0.01 g/mi. (2) FUEL ECONOMY--The fuel economy goal was 50 percent MPG improvement (combined city/highway) over the 1997 gasoline powered light truck or sport utility vehicle in the vehicle class for which this diesel engine is being designed to replace. The goal for fuel economy remained at 50 percent MPG improvement, even with the emissions goal revisions. (3) COOPERATIVE DEVELOPMENT--Regular design reviews of the engine program will be conducted with a vehicle manufacturer to insure that the concepts and design specifics are commercially feasible. (DaimlerChrysler has provided Cummins with this design review input.) Cummins has essentially completed a demonstration of proof-of-principle for a diesel engine platform using advanced combustion and fuel system technologies. Cummins reported very early progress in this project, evidence that new diesel engine technology had been developed that demonstrated the feasibility of the above emissions goals. Emissions levels of NOx = 0.4 g/mi and PM = 0.06 g/mi were demonstrated for a 5250 lb. test weight vehicle with passive aftertreatment only. These results were achieved using the

Development of Technologies for a High Efficiency, Very Low Emission, Diesel Engine for Light Trucks and Sport Utility Vehicles

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stang, John H.

1997-12-01

Cummins Inc., in partnership with the Department of Energy, has developed technology for a new highly efficient, very low emission, diesel engine for light trucks and sport utility vehicles. This work began in April 1997, and started with very aggressive goals for vehicles in the 5751 to 8500 pound GCW weight class. The primary program goals were as follows: (1) EMISSIONS NOx = 0.50 g/mi PM = 0.05 g/mi CO = 2.8 g/mi NMHC = 0.07 g/mi California decided to issue new and even tougher LEV II light truck regulations late in 1999. EPA also issued its lower Tier 2more » regulations late in 2000. The net result was that the targets for this diesel engine project were lowered, and these goals were eventually modified by the publication of Federal Tier 2 emission standards early in 2000 to the following: NOx = 0.07 g/mi PM = 0.01 g/mi (2) FUEL ECONOMY The fuel economy goal was 50 percent MPG improvement (combined city/highway) over the 1997 gasoline powered light truck or sport utility vehicle in the vehicle class for which this diesel engine is being designed to replace. The goal for fuel economy remained at 50 percent MPG improvement, even with the emissions goal revisions. (3) COOPERATIVE DEVELOPMENT Regular design reviews of the engine program will be conducted with a vehicle manufacturer to insure that the concepts and design specifics are commercially feasible. (DaimlerChrysler has provided Cummins with this design review input.) Cummins has essentially completed a demonstration of proof-of-principle for a diesel engine platform using advanced combustion and fuel system technologies. Cummins reported very early progress in this project, evidence that new diesel engine technology had been developed that demonstrated the feasibility of the above emissions goals. Emissions levels of NOx = 0.4 g/mi and PM = 0.06 g/mi were demonstrated for a 5250 lb. test weight vehicle with passive aftertreatment only. These results were achieved using the full chassis dynamometer FTP-75

Effects of the Effect of Ultra High Frequency Mobile Phone Radiation on Human Health.

PubMed

Moradi, Mosa; Naghdi, Nasrollah; Hemmati, Hamidreza; Asadi-Samani, Majid; Bahmani, Mahmoud

2016-05-01

Public and occupational exposure to electromagnetic fields due to the growing trend of electronic devices may cause adverse effects on human health. This paper describes the risk of mutation and sexual trauma and infertility in masculine sexual cell by mobile phone radiations. In this study, we measured the emitted dose from a radiofrequency device, such as switching high voltage at different frequencies using a scintillation detector. The switching high voltage power supply (HVPS) was built for the Single Photon Emission Computed Tomography (SPECT) system. For radiation dosimetry, we used an ALNOR scintillator that can measure gamma radiation. The simulation was performed by MATLAB software, and data from the International Commission on Non-Ionizing Radiation Protection (ICNIRP) were used to verify the simulation. We investigated the risks that result from the waves, according to a report by International Commission on Non Ionizing Radiation Protection (ICNIRP), to every organ of the body is defined by the beam and electromagnetic radiation from this electronic device on people. The results showed that the maximum personal dose over a 15-min period working at the mentioned HVPS did not exceed 0.31 μSV/h (with an aluminum shield). So, according to other sources of radiation, continuous working time of the system should not be more than 10 hours. Finally, a characteristic curve for secure working with modules at different frequencies was reported. The RF input signal to the body for maximum penetration depth (δ) and electromagnetic energy absorption rate (SAR) of biological tissue were obtained for each tissue. The results of this study and International Commission of Non Ionization Radiation Protection (ICNIRP) reports showed the people who spend more than 50 minutes a day using a cell phone could have early dementia or other thermal damage due to the burning of glucose in the brain.

High frequency oscillations in brain hemodynamic response

NASA Astrophysics Data System (ADS)

Akin, Ata; Bolay, Hayrunnisa

2007-07-01

Tight autoregulation of vessel tone guarantees proper delivery of nutrients to the tissues. This regulation is maintained at a more delicate level in the brain since any decrease in the supply of glucose and oxygen to neuronal tissues might lead to unrecoverable injury. Functional near infrared spectroscopy has been proposed as a new tool to monitor the cerebrovascular response during cognitive activity. We have observed that during a Stroop task three distinct oscillatory patterns govern the control of the cerebrovascular reactivity: very low frequency (0.02-0.05 Hz), low frequency (0.08-0.12 Hz) and high frequency (0.12-0.18 Hz). High frequency oscillations have been shown to be related to stress level of the subjects. Our findings indicate that as the stress level is increased so does the energy of the high frequency component indicating a higher stimulation from the autonomic nervous system.

Escherichia coli growth changes by the mediated effects after low-intensity electromagnetic irradiation of extremely high frequencies.

PubMed

Torgomyan, Heghine; Hovnanyan, Karlen; Trchounian, Armen

2013-04-01

Water is the major constituent of environmental medium and biological systems. The effects occurring in water as a result of low-intensity electromagnetic irradiation (EMI) in extremely high frequencies are supposed to be the primary mechanism to create conditions for biological responses. The EMI effects on Escherichia coli, after irradiation of their suspension, are most probably water-mediated. Indirect effects of EMI at 51.8, 53, 70.6, and 73 GHz frequencies on bacteria, through water, assay buffer (Tris-phosphate buffer with inorganic salts at low or moderate concentrations), or peptone growth medium were studied. The mediated effects of 70.6 and 73 GHz irradiated water, assay buffer, and growth medium on E. coli growth characteristics were insignificant. But the results were different for 51.8 and 53 GHz. EMI mediated effects on bacterial growth were clearly demonstrated. The effects were more strongly expressed with 53 GHz. Moreover, it was shown that 70.6 and 73 GHz similarly suppressed the cell growth after direct irradiation of E. coli in water or on solid medium. Interestingly, for 51.8 and 53 GHz the bacterial growth decreases after suspension irradiation was less, compared to the direct irradiation of bacteria on solid medium. Especially, it was also more expressed in case of 53 GHz. Also with electron microscopy, EMI-induced bacterial cell sizes and structure different changes were detected. In addition, the distinguished changes in surface tension, oxidation-reduction potential and pH of water, assay buffer, growth medium, and bacterial suspension were determined. They depended on EMI frequency used. The differences could be associated with the partial absorbance of EMI energy by the surrounding medium, which depends on a specific frequency. The results are crucial to understand biophysical mechanisms of EMI effects on bacteria.

High-frequency electromagnetic properties of soft magnetic metal-polyimide hybrid thin films

NASA Astrophysics Data System (ADS)

Kim, Sang Woo; Yoon, Chong S.

2007-09-01

Although there are a lot of demands for suppression of unwanted high-frequency electromagnetic noise in highly integrated electronic devices such as mobile phones and notebook computers, electromagnetic thin films that effectively work in the high-frequency range have still been underdeveloped. Soft magnetic metal-polyimide (PI) hybrid films with high electrical resistivity were prepared by thermal imidization and selective oxidation between the metal alloy layer and polyamic acid (PAA) layer. Electromagnetic properties of the hybrid thin films in the radio-frequency range were characterized by using the microstrip line method and were correlated with their material parameters. Although anisotropy field of the CoFe/NiFe hybrid film was two times lower than that of the NiFe hybrid film, the saturation magnetization of the CoFe/NiFe hybrid film was three times higher than that of the NiFe hybrid film. The CoFe/NiFe hybrid film showed higher power loss in the frequency range of 3-6 GHz compared to the NiFe hybrid film. The high power loss of the CoFe/NiFe hybrid film was caused by high relative permeability and high ferromagnetic resonance (FMR) frequency due to high saturation magnetization.

High-frequency Rayleigh-wave method

USGS Publications Warehouse

Xia, J.; Miller, R.D.; Xu, Y.; Luo, Y.; Chen, C.; Liu, J.; Ivanov, J.; Zeng, C.

2009-01-01

High-frequency (???2 Hz) Rayleigh-wave data acquired with a multichannel recording system have been utilized to determine shear (S)-wave velocities in near-surface geophysics since the early 1980s. This overview article discusses the main research results of high-frequency surface-wave techniques achieved by research groups at the Kansas Geological Survey and China University of Geosciences in the last 15 years. The multichannel analysis of surface wave (MASW) method is a non-invasive acoustic approach to estimate near-surface S-wave velocity. The differences between MASW results and direct borehole measurements are approximately 15% or less and random. Studies show that simultaneous inversion with higher modes and the fundamental mode can increase model resolution and an investigation depth. The other important seismic property, quality factor (Q), can also be estimated with the MASW method by inverting attenuation coefficients of Rayleigh waves. An inverted model (S-wave velocity or Q) obtained using a damped least-squares method can be assessed by an optimal damping vector in a vicinity of the inverted model determined by an objective function, which is the trace of a weighted sum of model-resolution and model-covariance matrices. Current developments include modeling high-frequency Rayleigh-waves in near-surface media, which builds a foundation for shallow seismic or Rayleigh-wave inversion in the time-offset domain; imaging dispersive energy with high resolution in the frequency-velocity domain and possibly with data in an arbitrary acquisition geometry, which opens a door for 3D surface-wave techniques; and successfully separating surface-wave modes, which provides a valuable tool to perform S-wave velocity profiling with high-horizontal resolution. ?? China University of Geosciences (Wuhan) and Springer-Verlag GmbH 2009.

High-Frequency Percussive Ventilation Revisited

DTIC Science & Technology

2010-01-01

be implemented. ‡ Follow the reverse of the ventilation sequence if respiratory alkalosis develops—however, start at ventilation goal sequence 1 not at...High-frequency percussive ventilation (HFPV) has demonstrated a potential role as a rescue option for refractory acute respiratory distress syndrome...frequency percussive ventilation (HFPV) has demon- strated a potential role as a salvage option for refrac- tory acute respiratory distress syndrome

Effects of broad frequency vibration on cultured osteoblasts

NASA Technical Reports Server (NTRS)

Tanaka, Shigeo M.; Li, Jiliang; Duncan, Randall L.; Yokota, Hiroki; Burr, David B.; Turner, Charles H.

2003-01-01

Bone is subjected in vivo to both high amplitude, low frequency strain, incurred by locomotion, and to low amplitude, broad frequency strain. The biological effects of low amplitude, broad frequency strain are poorly understood. To evaluate the effects of low amplitude strains ranging in frequency from 0 to 50 Hz on osteoblastic function, we seeded MC3T3-E1 cells into collagen gels and applied the following loading protocols for 3 min per day for either 3 or 7 days: (1) sinusoidal strain at 3 Hz, with 0-3000 microstrain peak-to-peak followed by 0.33 s resting time, (2) "broad frequency vibration" of low amplitude strain (standard deviation of 300 microstrain) including frequency components from 0 to 50 Hz, and (3) sinusoidal strain combined with broad frequency vibration (S + V). The cells were harvested on day 4 or 8. We found that the S + V stimulation significantly repressed cell proliferation by day 8. Osteocalcin mRNA was up-regulated 2.6-fold after 7 days of S + V stimulation, and MMP-9 mRNA was elevated 1.3-fold after 3 days of vibration alone. Sinusoidal stimulation alone did not affect the cell responses. No differences due to loading were observed in alkaline phosphatase activity and in mRNA levels of type I collagen, osteopontin, connexin 43, MMPs-1A, -3, -13. These results suggest that osteoblasts are more sensitive to low amplitude, broad frequency strain, and this kind of strain could sensitize osteoblasts to high amplitude, low frequency strain. This suggestion implies a potential contribution of stochastic resonance to the mechanical sensitivity of osteoblasts. Copyright 2002 Elsevier Science Ltd.

Lateralization of high-frequency transposed stimuli under conditions of binaural interference

NASA Astrophysics Data System (ADS)

Bernstein, Leslie R.; Trahiotis, Constantine

2005-04-01

The purpose of this study was to determine whether binaural interference would occur if ITD-based extents of laterality were measured using high-frequency transposed stimuli as targets. The results of an earlier study [L. R. Bernstein and C. Trahiotis, J. Acoust. Soc. Am. 116, 3062-3069 (2004)], which focused on threshold-ITDs rather than extents of laterality, suggested that high-frequency transposed stimuli might be immune to binaural interference effects resulting from the addition of a spectrally-remote, low-frequency interferer. In contrast to the earlier findings, the data from this study indicate that high-frequency transposed targets can, indeed, be susceptible to binaural interference. High-frequency transposed targets, even when presented along with an interferer, yielded greater extents of ITD-based laterality than did Gaussian noise targets presented in isolation. That is, the enhanced potency of ITDs conveyed by transposed stimuli persisted even in the presence of a low-frequency interferer. Predictions made using an extension of the model of Heller and Trahiotis [L. M. Heller and C. Trahiotis, J. Acoust. Soc. Am. 99, 3632-3637 (1996)] accounted well for binaural interference obtained with conventional Gaussian noise targets but generally over-predicted the amounts of interference found with the transposed targets.

Effect of laser frequency noise on fiber-optic frequency reference distribution

NASA Technical Reports Server (NTRS)

Logan, R. T., Jr.; Lutes, G. F.; Maleki, L.

1989-01-01

The effect of the linewidth of a single longitude-mode laser on the frequency stability of a frequency reference transmitted over a single-mode optical fiber is analyzed. The interaction of the random laser frequency deviations with the dispersion of the optical fiber is considered to determine theoretically the effect on the Allan deviation (square root of the Allan variance) of the transmitted frequency reference. It is shown that the magnitude of this effect may determine the limit of the ultimate stability possible for frequency reference transmission on optical fiber, but is not a serious limitation to present system performance.

HIGH CURRENT RADIO FREQUENCY ION SOURCE

DOEpatents

Abdelaziz, M.E.

1963-04-01

This patent relates to a high current radio frequency ion source. A cylindrical plasma container has a coil disposed around the exterior surface thereof along the longitudinal axis. Means are provided for the injection of an unionized gas into the container and for applying a radio frequency signal to the coil whereby a radio frequency field is generated within the container parallel to the longitudinal axis thereof to ionize the injected gas. Cathode and anode means are provided for extracting transverse to the radio frequency field from an area midway between the ends of the container along the longitudinal axis thereof the ions created by said radio frequency field. (AEC)

Proposed Ultra-High Sensitivity High-Frequency Gravitational Wave Detector

NASA Astrophysics Data System (ADS)

Baker, Robert M. L.; Stephenson, Gary V.; Li, Fangyu

2008-01-01

The paper discusses the proposed improvement of a High-Frequency Relic Gravitational Wave (HFRGW) detector designed by Li, Baker, Fang, Stephenson and Chen in order to greatly improve its sensitivity. The improved detector is inspired by the Laser Interferometer Gravitational Observatory or LIGO, but is sensitive to the high-frequency end of the gravitational-wave spectrum. As described in prior papers it utilizes the Gertsenshtein effect, which introduces the conversion of gravitational waves to electromagnetic (EM) waves in the presence of a static magnetic field. Such a conversion, if it leads to photons moving in a direction perpendicular to the plane of the EM waves and the magnetic field, will allow for ultra-high sensitivity HFRGW detection. The use of sensitive microwave, single photon detectors such as a circuit QED and/or the Rydberg Atom Cavity Detector, or off-the-shelf detectors, could lead to such detection. When the EM-detection photons are focused at the microwave detectors by fractal-membrane reflectors sensitivity is also improved. Noise sources external to the HFRGW detector will be eliminated by placing a tight mosaic of superconducting tiles (e.g., YBCO) and/or fractal membranes on the interior surface of the detector's cryogenic containment vessel in order to provide a perfect Faraday cage. Internal thermal noise will be eliminated by means of a microwave absorbing (or reflecting) interior enclosure shaped to conform to a high-intensity continuous microwave Gaussian beam (GB), will reduce any background photon flux (BPF) noise radiated normal to the GB's axis. Such BPF will be further attenuated by a series of microwave absorbing baffles forming tunnels to the sensitive microwave detectors on each side of the GB and at right angles to the static magnetic field. A HFGW detector of bandwidth of 1 KHz to 10 KHz or less in the GHz band has been selected. It is concluded that the utilization of the new ultra-high-sensitivity microwave detectors

Planck 2013 results. VI. High Frequency Instrument data processing

NASA Astrophysics Data System (ADS)

Planck Collaboration; Ade, P. A. R.; Aghanim, N.; Armitage-Caplan, C.; Arnaud, M.; Ashdown, M.; Atrio-Barandela, F.; Aumont, J.; Baccigalupi, C.; Banday, A. J.; Barreiro, R. B.; Battaner, E.; Benabed, K.; Benoît, A.; Benoit-Lévy, A.; Bernard, J.-P.; Bersanelli, M.; Bielewicz, P.; Bobin, J.; Bock, J. J.; Bond, J. R.; Borrill, J.; Bouchet, F. R.; Boulanger, F.; Bowyer, J. W.; Bridges, M.; Bucher, M.; Burigana, C.; Cardoso, J.-F.; Catalano, A.; Chamballu, A.; Chary, R.-R.; Chen, X.; Chiang, H. C.; Chiang, L.-Y.; Christensen, P. R.; Church, S.; Clements, D. L.; Colombi, S.; Colombo, L. P. L.; Combet, C.; Couchot, F.; Coulais, A.; Crill, B. P.; Curto, A.; Cuttaia, F.; Danese, L.; Davies, R. D.; Davis, R. J.; de Bernardis, P.; de Rosa, A.; de Zotti, G.; Delabrouille, J.; Delouis, J.-M.; Désert, F.-X.; Dickinson, C.; Diego, J. M.; Dole, H.; Donzelli, S.; Doré, O.; Douspis, M.; Dunkley, J.; Dupac, X.; Efstathiou, G.; Enßlin, T. A.; Eriksen, H. K.; Finelli, F.; Forni, O.; Frailis, M.; Fraisse, A. A.; Franceschi, E.; Galeotta, S.; Ganga, K.; Giard, M.; Giardino, G.; Girard, D.; Giraud-Héraud, Y.; González-Nuevo, J.; Górski, K. M.; Gratton, S.; Gregorio, A.; Gruppuso, A.; Gudmundsson, J. E.; Hansen, F. K.; Hanson, D.; Harrison, D.; Helou, G.; Henrot-Versillé, S.; Herent, O.; Hernández-Monteagudo, C.; Herranz, D.; Hildebrandt, S. R.; Hivon, E.; Hobson, M.; Holmes, W. A.; Hornstrup, A.; Hou, Z.; Hovest, W.; Huffenberger, K. M.; Hurier, G.; Jaffe, A. H.; Jaffe, T. R.; Jones, W. C.; Juvela, M.; Keihänen, E.; Keskitalo, R.; Kisner, T. S.; Kneissl, R.; Knoche, J.; Knox, L.; Kunz, M.; Kurki-Suonio, H.; Lagache, G.; Lamarre, J.-M.; Lasenby, A.; Laureijs, R. J.; Lawrence, C. R.; Le Jeune, M.; Leonardi, R.; Leroy, C.; Lesgourgues, J.; Liguori, M.; Lilje, P. B.; Linden-Vørnle, M.; López-Caniego, M.; Lubin, P. M.; Macías-Pérez, J. F.; MacTavish, C. J.; Maffei, B.; Mandolesi, N.; Maris, M.; Marleau, F.; Marshall, D. J.; Martin, P. G.; Martínez-González, E.; Masi, S.; Massardi, M.; Matarrese, S.; Matthai, F.; Mazzotta, P.; McGehee, P.; Meinhold, P. R.; Melchiorri, A.; Melot, F.; Mendes, L.; Mennella, A.; Migliaccio, M.; Mitra, S.; Miville-Deschênes, M.-A.; Moneti, A.; Montier, L.; Morgante, G.; Mortlock, D.; Mottet, S.; Munshi, D.; Murphy, J. A.; Naselsky, P.; Nati, F.; Natoli, P.; Netterfield, C. B.; Nørgaard-Nielsen, H. U.; North, C.; Noviello, F.; Novikov, D.; Novikov, I.; Orieux, F.; Osborne, S.; Oxborrow, C. A.; Paci, F.; Pagano, L.; Pajot, F.; Paladini, R.; Paoletti, D.; Pasian, F.; Patanchon, G.; Perdereau, O.; Perotto, L.; Perrotta, F.; Piacentini, F.; Piat, M.; Pierpaoli, E.; Pietrobon, D.; Plaszczynski, S.; Pointecouteau, E.; Polenta, G.; Ponthieu, N.; Popa, L.; Poutanen, T.; Pratt, G. W.; Prézeau, G.; Prunet, S.; Puget, J.-L.; Rachen, J. P.; Racine, B.; Reach, W. T.; Rebolo, R.; Reinecke, M.; Remazeilles, M.; Renault, C.; Ricciardi, S.; Riller, T.; Ristorcelli, I.; Rocha, G.; Rosset, C.; Roudier, G.; Rowan-Robinson, M.; Rusholme, B.; Sanselme, L.; Santos, D.; Sauvé, A.; Savini, G.; Scott, D.; Shellard, E. P. S.; Spencer, L. D.; Starck, J.-L.; Stolyarov, V.; Stompor, R.; Sudiwala, R.; Sureau, F.; Sutton, D.; Suur-Uski, A.-S.; Sygnet, J.-F.; Tauber, J. A.; Tavagnacco, D.; Techene, S.; Terenzi, L.; Tomasi, M.; Tristram, M.; Tucci, M.; Umana, G.; Valenziano, L.; Valiviita, J.; Van Tent, B.; Vibert, L.; Vielva, P.; Villa, F.; Vittorio, N.; Wade, L. A.; Wandelt, B. D.; White, S. D. M.; Yvon, D.; Zacchei, A.; Zonca, A.

2014-11-01

Wedescribe the processing of the 531 billion raw data samples from the High Frequency Instrument (HFI), which we performed to produce six temperature maps from the first 473 days of Planck-HFI survey data. These maps provide an accurate rendition of the sky emission at 100, 143, 217, 353, 545, and 857GHz with an angular resolution ranging from 9.´7 to 4.´6. The detector noise per (effective) beam solid angle is respectively, 10, 6 , 12, and 39 μK in the four lowest HFI frequency channels (100-353GHz) and 13 and 14 kJy sr-1 in the 545 and 857 GHz channels. Relative to the 143 GHz channel, these two high frequency channels are calibrated to within 5% and the 353 GHz channel to the percent level. The 100 and 217 GHz channels, which together with the 143 GHz channel determine the high-multipole part of the CMB power spectrum (50 <ℓ < 2500), are calibrated relative to 143 GHz to better than 0.2%.

An Analysis of the High Frequency Vibrations in Early Thematic Mapper Scenes

NASA Technical Reports Server (NTRS)

Kogut, J.; Larduinat, E.

1984-01-01

The potential effects of high frequency vibrations on the final Thematic Mapper (TM) image are evaluated for 26 scenes. The angular displacements of the TM detectors from their nominal pointing directions as measured by the TM Angular Displacement Sensor (ADS) and the spacecraft Dry Rotor Inertial Reference Unit (DRIRU) give data on the along scan and cross scan high frequency vibrations present in each scan of a scene. These measurements are to find the maximum overlap and underlap between successive scans, and to analyze the spectrum of the high frequency vibrations acting on the detectors. The Fourier spectrum of the along scan and cross scan vibrations for each scene also evaluated. The spectra of the scenes examined indicate that the high frequency vibrations arise primarily from the motion of the TM and MSS mirrors, and that their amplitudes are well within expected ranges.

High frequency x-ray generator basics.

PubMed

Sobol, Wlad T

2002-02-01

The purpose of this paper is to present basic functional principles of high frequency x-ray generators. The emphasis is put on physical concepts that determine the engineering solutions to the problem of efficient generation and control of high voltage power required to drive the x-ray tube. The physics of magnetically coupled circuits is discussed first, as a background for the discussion of engineering issues related to high-frequency power transformer design. Attention is paid to physical processes that influence such factors as size, efficiency, and reliability of a high voltage power transformer. The basic electrical circuit of a high frequency generator is analyzed next, with focus on functional principles. This section investigates the role and function of basic components, such as power supply, inverter, and voltage doubler. Essential electronic circuits of generator control are then examined, including regulation of voltage, current and timing of electrical power delivery to the x-ray tube. Finally, issues related to efficient feedback control, including basic design of the AEC circuitry are reviewed.

High-frequency modulation of ion-acoustic waves.

NASA Technical Reports Server (NTRS)

Albright, N. W.

1972-01-01

A large amplitude, high-frequency electromagnetic oscillation is impressed on a nonrelativistic, collisionless plasma from an external source. The frequency is chosen to be far from the plasma frequency (in fact, lower). The resulting electron velocity distribution function strongly modifies the propagation of ion-acoustic waves parallel to the oscillating electric field. The complex frequency is calculated numerically.

WAIS-III FSIQ and GAI in ability-memory discrepancy analysis.

PubMed

Glass, Laura A; Bartels, Jared M; Ryan, Joseph J

2009-01-01

The present investigation compares WAIS-III FSIQ-WMS-III with GAI-WMS-III discrepancies in 135 male inpatients with suspected memory impairment. Full Scale IQ and GAI scores were highly correlated, r= .96, with mean values of 92.10 and 93.59, respectively. Additional analyses with the ability composites compared to each WMS-III index (IMI, GMI, and DMI), the GAI consistently produced larger difference scores than did the FSIQ; however, effect sizes were relatively small (ES= .12). Lastly, case-by-case analyses demonstrated concordance rates of 86% for the FSIQ-IMI and GAI-IMI comparisons, 85% for the FSIQ-GMI and GAI-GMI, and 82% for the FSIQ-DMI and GAI-DMI.

Positional stability and radial dynamics of sonoluminescent bubbles under bi-harmonic driving: Effect of the high-frequency component and its relative phase.

PubMed

Rosselló, J M; Dellavale, D; Bonetto, F J

2016-07-01

The use of bi-frequency driving in sonoluminescence has proved to be an effective way to avoid the spatial instability (pseudo-orbits) developed by bubbles in systems with high viscous liquids like sulfuric or phosphoric acids. In this work, we present extensive experimental and numerical evidence in order to assess the effect of the high frequency component (PAc(HF)) of a bi-harmonic acoustic pressure field on the dynamic of sonoluminescent bubbles in an aqueous solution of sulfuric acid. The present study is mainly focused on the role of the harmonic frequency (Nf0) and the relative phase between the two frequency components (φb) of the acoustic field on the spatial, positional and diffusive stability of the bubbles. The results presented in this work were analyzed by means of three different approaches. First, we discussed some qualitative considerations about the changes observed in the radial dynamics, and the stability of similar bubbles under distinct bi-harmonic drivings. Later, we have investigated, through a series of numerical simulations, how the use of high frequency harmonic components of different order N, affects the positional stability of the SL bubbles. Furthermore, the influence of φb in their radius temporal evolution is systematically explored for harmonics ranging from the second to the fifteenth harmonic (N=2-15). Finally, a multivariate analysis based on the covariance method is performed to study the dependences among the parameters characterizing the SL bubble. Both experimental and numerical results indicate that the impact of PAc(HF) on the positional instability and the radial dynamics turns to be progressively negligible as the order of the high frequency harmonic component grows (i.e. N ≫ 1), however its effectiveness on the reduction of the spatial instability remains unaltered or even improved. Copyright © 2016 Elsevier B.V. All rights reserved.

Improvement of Olfactory Function With High Frequency Non-invasive Auricular Electrostimulation in Healthy Humans

PubMed Central

Maharjan, Ashim; Wang, Eunice; Peng, Mei; Cakmak, Yusuf O.

2018-01-01

In past literature on animal models, invasive vagal nerve stimulation using high frequencies has shown to be effective at modulating the activity of the olfactory bulb (OB). Recent advances in invasive vagal nerve stimulation in humans, despite previous findings in animal models, used low frequency stimulation and found no effect on the olfactory functioning. The present article aimed to test potential effects of non-invasive, high and low frequency vagal nerve stimulation in humans, with supplementary exploration of the orbitofrontal cortex using near-infrared spectroscopy (NIRS). Healthy, male adult participants (n = 18) performed two olfactory tests [odor threshold test (OTT) and supra-threshold test (STT)] before and after receiving high-, low frequency vagal nerve stimulation and placebo (no stimulation). Participant's olfactory functioning was monitored using NIRS, and assessed with two behavioral olfactory tests. NIRS data of separate stimulation parameters were statistically analyzed using repeated-measures ANOVA across different stages. Data from olfactory tests were analyzed using paired parametric and non-parametric statistical tests. Only high frequency, non-invasive vagal nerve stimulation was able to positively modulate the performance of the healthy participants in the STT (p = 0.021, Wilcoxon sign-ranked test), with significant differences in NIRS (p = 0.014, post-hoc with Bonferroni correction) recordings of the right hemispheric, orbitofrontal cortex. The results from the current article implore further exploration of the neurocircuitry involved under vagal nerve stimulation and the effects of non-invasive, high frequency, vagal nerve stimulation toward olfactory dysfunction which showcase in Parkinson's and Alzheimer's Diseases. Despite the sufficient effect size (moderate effect, correlation coefficient (r): 0.39 for the STT) of the current study, future research should replicate the current findings with a larger cohort. PMID:29740266

Improvement of Olfactory Function With High Frequency Non-invasive Auricular Electrostimulation in Healthy Humans.

PubMed

Maharjan, Ashim; Wang, Eunice; Peng, Mei; Cakmak, Yusuf O

2018-01-01

In past literature on animal models, invasive vagal nerve stimulation using high frequencies has shown to be effective at modulating the activity of the olfactory bulb (OB). Recent advances in invasive vagal nerve stimulation in humans, despite previous findings in animal models, used low frequency stimulation and found no effect on the olfactory functioning. The present article aimed to test potential effects of non-invasive, high and low frequency vagal nerve stimulation in humans, with supplementary exploration of the orbitofrontal cortex using near-infrared spectroscopy (NIRS). Healthy, male adult participants ( n = 18) performed two olfactory tests [odor threshold test (OTT) and supra-threshold test (STT)] before and after receiving high-, low frequency vagal nerve stimulation and placebo (no stimulation). Participant's olfactory functioning was monitored using NIRS, and assessed with two behavioral olfactory tests. NIRS data of separate stimulation parameters were statistically analyzed using repeated-measures ANOVA across different stages. Data from olfactory tests were analyzed using paired parametric and non-parametric statistical tests. Only high frequency, non-invasive vagal nerve stimulation was able to positively modulate the performance of the healthy participants in the STT ( p = 0.021, Wilcoxon sign-ranked test), with significant differences in NIRS ( p = 0.014, post-hoc with Bonferroni correction ) recordings of the right hemispheric, orbitofrontal cortex. The results from the current article implore further exploration of the neurocircuitry involved under vagal nerve stimulation and the effects of non-invasive, high frequency, vagal nerve stimulation toward olfactory dysfunction which showcase in Parkinson's and Alzheimer's Diseases. Despite the sufficient effect size (moderate effect, correlation coefficient (r): 0.39 for the STT) of the current study, future research should replicate the current findings with a larger cohort.

High-efficiency surface plasmonic polariton waveguides with enhanced low-frequency performance in microwave frequencies.

PubMed

Zhang, Dawei; Zhang, Kuang; Wu, Qun; Ding, Xumin; Sha, Xuejun

2017-02-06

In this paper, a planar waveguide based on spoof surface plasmon polaritons (SSPPs) with metals on both sides of the corrugated strip as grounds is firstly proposed in microwave region. Simple and efficient conversion between guided waves and SSPPs is realized by gradient corrugated strip with grounds on both sides. Compared with plasmonic waveguide with flaring ground [Laser Photonics Rev. 8, 146 (2014)], the addition of grounds suppresses the radiation loss effectively and improves the low-frequency performance with tighter field confinement, which leads to a wider operating bandwidth. Moreover, as the asymptotic frequency of SSPPs decreasing, the confinement of SSPPs is further enhanced by a defected ground structure (DGS), which is achieved by the periodic grooves symmetrical to those on the corrugated strip. Therefore, miniaturization of the proposed waveguide can be realized. Measured results validate both high efficiency of momentum and impedance matching and enhanced performance in the region of lower frequencies with the wave vectors close to those in free space. Such results have significant values in plasmonic functional devices and integrated circuits in microwave frequencies.

Amplitude-frequency effect of Y-cut langanite and langatate.

PubMed

Kim, Yoonkee

2003-12-01

Amplitude-frequency effect of a Y-cut langanite (LGN) resonator and a Y-cut langatate (LGT) resonator were measured. The frequency shifts from the baseline frequency with 1 mA were measured as a function of drive currents up to 28 mA. High-drive current shifted the frequency, but it also heated the crystal locally, causing temperature-related frequency changes. The local heat transfer and its influence on the frequency were analyzed. The amplitude-frequency shift was effectively measured, and was not affected by the temperature-related frequency changes. The 3rd, 5th, and 7th overtones (OT's) were found to behave as soft springs, i.e., resonant frequency decreases as drive current increases. The drive sensitivity coefficients of the 3rd and 5th OT's are in the vicinity of -2 ppb/mA2 for both resonators. The 7th OT's are higher than the other OT's: -5 approximately -7 ppb/mA2. The lowest drive sensitivity is -1.2 ppb/mA2 on the 5th OT of the LGT.

Mutational jackpot events generate effective frequency-dependent selection in adapting populations

NASA Astrophysics Data System (ADS)

Hallatschek, Oskar

The site-frequency spectrum is one the most easily measurable quantities that characterize the genetic diversity of a population. While most neutral models predict that site frequency spectra should decay with increasing frequency, a high-frequency uptick has been reported in many populations. Anomalies in the high-frequency tail are particularly unsettling because the highest frequencies can be measured with greatest accuracy. Here, we show that an uptick in the spectrum of neutral mutations generally arises when mutant frequencies are dominated by rare jackpot events, mutational events with large descendant numbers. This leads to an effective pattern of frequency-dependent selection (or unstable internal equilibrium at one half frequency) that causes an accumulation of high-frequency polymorphic sites. We reproduce the known uptick occurring for recurrent hitchhiking (genetic draft) as well as rapid adaptation, and (in the future) generalize the shape of the high-frequency tail to other scenarios that are dominated by jackpot events, such as frequent range expansions. We also tackle (in the future) the inverse approach to use the high-frequency uptick for learning about the tail of the offspring number distribution. Positively selected alleles need to surpass, typically, an u NSF Career Award (PoLS), NIH NIGMS R01, Simons Foundation.

The Sterilization Effect of Cooperative Treatment of High Voltage Electrostatic Field and Variable Frequency Pulsed Electromagnetic Field on Heterotrophic Bacteria in Circulating Cooling Water

NASA Astrophysics Data System (ADS)

Gao, Xuetong; Liu, Zhian; Zhao, Judong

2018-01-01

Compared to other treatment of industrial circulating cooling water in the field of industrial water treatment, high-voltage electrostatic field and variable frequency pulsed electromagnetic field co-sterilization technology, an advanced technology, is widely used because of its special characteristics--low energy consumption, nonpoisonous and environmentally friendly. In order to get a better cooling water sterilization effect under the premise of not polluting the environment, some experiments about sterilization of heterotrophic bacteria in industrial circulating cooling water by cooperative treatment of high voltage electrostatic field and variable frequency pulsed electromagnetic field were carried out. The comparison experiment on the sterilization effect of high-voltage electrostatic field and variable frequency pulsed electromagnetic field co-sterilization on heterotrophic bacteria in industrial circulating cooling water was carried out by change electric field strength and pulse frequency. The results show that the bactericidal rate is selective to the frequency and output voltage, and the heterotrophic bacterium can only kill under the condition of sweep frequency range and output voltage. When the voltage of the high voltage power supply is 4000V, the pulse frequency is 1000Hz and the water temperature is 30°C, the sterilization rate is 48.7%, the sterilization rate is over 90%. Results of this study have important guiding significance for future application of magnetic field sterilization.

The Influence of High-Frequency Envelope Information on Low-Frequency Vowel Identification in Noise

PubMed Central

2016-01-01

Vowel identification in noise using consonant-vowel-consonant (CVC) logatomes was used to investigate a possible interplay of speech information from different frequency regions. It was hypothesized that the periodicity conveyed by the temporal envelope of a high frequency stimulus can enhance the use of the information carried by auditory channels in the low-frequency region that share the same periodicity. It was further hypothesized that this acts as a strobe-like mechanism and would increase the signal-to-noise ratio for the voiced parts of the CVCs. In a first experiment, different high-frequency cues were provided to test this hypothesis, whereas a second experiment examined more closely the role of amplitude modulations and intact phase information within the high-frequency region (4–8 kHz). CVCs were either natural or vocoded speech (both limited to a low-pass cutoff-frequency of 2.5 kHz) and were presented in stationary 3-kHz low-pass filtered masking noise. The experimental results did not support the hypothesized use of periodicity information for aiding low-frequency perception. PMID:26730702

The locus of word frequency effects in skilled spelling-to-dictation.

PubMed

Chua, Shi Min; Liow, Susan J Rickard

2014-01-01

In spelling-to-dictation tasks, skilled spellers consistently initiate spelling of high-frequency words faster than that of low-frequency words. Tainturier and Rapp's model of spelling shows three possible loci for this frequency effect: spoken word recognition, orthographic retrieval, and response execution of the first letter. Thus far, researchers have attributed the effect solely to orthographic retrieval without considering spoken word recognition or response execution. To investigate word frequency effects at each of these three loci, Experiment 1 involved a delayed spelling-to-dictation task and Experiment 2 involved a delayed/uncertain task. In Experiment 1, no frequency effect was found in the 1200-ms delayed condition, suggesting that response execution is not affected by word frequency. In Experiment 2, no frequency effect was found in the delayed/uncertain task that reflects the orthographic retrieval, whereas a frequency effect was found in the comparison immediate/uncertain task that reflects both spoken word recognition and orthographic retrieval. The results of this two-part study suggest that frequency effects in spoken word recognition play a substantial role in skilled spelling-to-dictation. Discrepancies between these findings and previous research, and the limitations of the present study, are discussed.

MS2 and ΦX174 inactivation by high frequency ultrasound

NASA Astrophysics Data System (ADS)

Manariotis, I. D.; Syngouna, V.; Chrysikopoulos, C. V.

2012-04-01

Biocolloid inactivation in water with the use of ultrasound can be quite effective, because the implosion of cavitation bubbles can generate high temperatures and pressures at the heart of collapsed bubbles. Biocolloid inactivation by cavitation takes place due to a combination of simultaneously acting processes involving mechanical effects (caused by turbulence generation, microstreaming, liquid circulation currents, and shear stresses), chemical effects of cavitation (generation of active free radicals), and heat effects (generation of local hot spots). Generally, the mechanical effects are more responsible for biocolloid disinfection, whereas the chemical and heat effects play only a supporting role. The present study focuses on inactivation of MS2 and ΦΧ174 at three different relatively high frequencies (i.e. 582, 862, and 1142 kHz). The experimental results indicate that, for all three frequencies and power input of 133 W, both phages were at least 90% inactivated after 60 min of sonication.

High Frequency Acoustic Propagation using Level Set Methods

DTIC Science & Technology

2007-01-01

solution of the high frequency approximation to the wave equation. Traditional solutions to the Eikonal equation in high frequency acoustics are...the Eikonal equation derived from the high frequency approximation to the wave equation, ucuH ∇±=∇ )(),( xx , with the nonnegative function c(x...For simplicity, we only consider the case ucuH ∇+=∇ )(),( xx . Two difficulties must be addressed when solving the Eikonal equation in a fixed

Apparatus for measuring high frequency currents

NASA Technical Reports Server (NTRS)

Hagmann, Mark J. (Inventor); Sutton, John F. (Inventor)

2003-01-01

An apparatus for measuring high frequency currents includes a non-ferrous core current probe that is coupled to a wide-band transimpedance amplifier. The current probe has a secondary winding with a winding resistance that is substantially smaller than the reactance of the winding. The sensitivity of the current probe is substantially flat over a wide band of frequencies. The apparatus is particularly useful for measuring exposure of humans to radio frequency currents.

The Importance of High Frequency Observations for the SKA

NASA Astrophysics Data System (ADS)

Welch, William J.

2007-12-01

The plan for the Square Kilometer Array (SKA) is one or more very large arrays operating in two or more contiguous frequency bands: roughly 15 - 90 MHz, 120 - 500 MHz, and 500 MHz - 25 GHz. The last band may be further divided into roughly 500 MHz - 1.5 GHz and 1.5 - 25 GHz. Construction costs may delay or forgo one or more of these bands. We argue that the entire high frequency band is of special importance for astronomy both in the local universe and at great distances and early times. One of the Key Science Projects, the Cradle of Life, requires high sensitivity and resolution at frequencies up to 20 GHz for the study of forming disks around new stars with disk opacities too great for millimeter wave observations. The larger issue of star formation, a poorly understood area, will also benefit from high sensitivity observations at short cm wavelengths. Magnetic field measurements through the Zeeman effect in the densest star forming gas are best done using tracers such as CCS at frequencies of 11 and 22 GHz. The wide frequency range of the SKA permits the observation of multiple rotational transitions of long chain molecules, providing accurate measures of both gas densities and temperatures. The wide field of view will permit large scale surveys of entire star forming clouds revealing, at high resolution, the formation of clusters of pre-protostellar stars and class 0-2 protostars in line radiation. The continuum cm wave radiation will reveal the growth of grains in disks. On the larger scale, observations of CO at high redshifts will trace the evolution of star formation and the formation of metals back to the Epic of Reionization.

Searching for Effective Training Solutions for Firefighting: The Analysis of Emergency Responses and Line of Duty Death Reports for Low Frequency, High Risk Events

DTIC Science & Technology

2017-09-01

whether emergency incidents connected to low frequency and high risk events contain sufficient warning signs or indicators of imminent catastrophic... high risk events contain sufficient warning signs or indicators of imminent catastrophic events, if firefighters could identify them, and if there...EFFECTIVE TRAINING SOLUTIONS FOR FIREFIGHTING: THE ANALYSIS OF EMERGENCY RESPONSES AND LINE OF DUTY DEATH REPORTS FOR LOW FREQUENCY, HIGH RISK EVENTS

Effects of Lexicality and Word Frequency on Brain Activation in Dyslexic Readers

ERIC Educational Resources Information Center

Heim, Stefan; Wehnelt, Anke; Grande, Marion; Huber, Walter; Amunts, Katrin

2013-01-01

We investigated the neural basis of lexical access to written stimuli in adult dyslexics and normal readers via the Lexicality effect (pseudowords greater than words) and the Frequency effect (low greater than high frequent words). The participants read aloud German words (with low or high lexical frequency) or pseudowords while being scanned. In…

Inverter design for high frequency power distribution

NASA Technical Reports Server (NTRS)

King, R. J.

1985-01-01

A class of simple resonantly commutated inverters are investigated for use in a high power (100 KW - 1000 KW) high frequency (10 KHz - 20 KHz) AC power distribution system. The Mapham inverter is found to provide a unique combination of large thyristor turn-off angle and good utilization factor, much better than an alternate 'current-fed' inverter. The effects of loading the Mapham inverter entirely with rectifier loads are investigated by simulation and with an experimental 3 KW 20 KHz inverter. This inverter is found to be well suited to a power system with heavy rectifier loading.

Multiscale Thermo-Mechanical Design and Analysis of High Frequency and High Power Vacuum Electron Devices

NASA Astrophysics Data System (ADS)

Gamzina, Diana

Diana Gamzina March 2016 Mechanical and Aerospace Engineering Multiscale Thermo-Mechanical Design and Analysis of High Frequency and High Power Vacuum Electron Devices Abstract A methodology for performing thermo-mechanical design and analysis of high frequency and high average power vacuum electron devices is presented. This methodology results in a "first-pass" engineering design directly ready for manufacturing. The methodology includes establishment of thermal and mechanical boundary conditions, evaluation of convective film heat transfer coefficients, identification of material options, evaluation of temperature and stress field distributions, assessment of microscale effects on the stress state of the material, and fatigue analysis. The feature size of vacuum electron devices operating in the high frequency regime of 100 GHz to 1 THz is comparable to the microstructure of the materials employed for their fabrication. As a result, the thermo-mechanical performance of a device is affected by the local material microstructure. Such multiscale effects on the stress state are considered in the range of scales from about 10 microns up to a few millimeters. The design and analysis methodology is demonstrated on three separate microwave devices: a 95 GHz 10 kW cw sheet beam klystron, a 263 GHz 50 W long pulse wide-bandwidth sheet beam travelling wave tube, and a 346 GHz 1 W cw backward wave oscillator.

The highs and lows of object impossibility: effects of spatial frequency on holistic processing of impossible objects.

PubMed

Freud, Erez; Avidan, Galia; Ganel, Tzvi

2015-02-01

Holistic processing, the decoding of a stimulus as a unified whole, is a basic characteristic of object perception. Recent research using Garner's speeded classification task has shown that this processing style is utilized even for impossible objects that contain an inherent spatial ambiguity. In particular, similar Garner interference effects were found for possible and impossible objects, indicating similar holistic processing styles for the two object categories. In the present study, we further investigated the perceptual mechanisms that mediate such holistic representation of impossible objects. We relied on the notion that, whereas information embedded in the high-spatial-frequency (HSF) content supports fine-detailed processing of object features, the information conveyed by low spatial frequencies (LSF) is more crucial for the emergence of a holistic shape representation. To test the effects of image frequency on the holistic processing of impossible objects, participants performed the Garner speeded classification task on images of possible and impossible cubes filtered for their LSF and HSF information. For images containing only LSF, similar interference effects were observed for possible and impossible objects, indicating that the two object categories were processed in a holistic manner. In contrast, for the HSF images, Garner interference was obtained only for possible, but not for impossible objects. Importantly, we provided evidence to show that this effect could not be attributed to a lack of sensitivity to object possibility in the LSF images. Particularly, even for full-spectrum images, Garner interference was still observed for both possible and impossible objects. Additionally, performance in an object classification task revealed high sensitivity to object possibility, even for LSF images. Taken together, these findings suggest that the visual system can tolerate the spatial ambiguity typical to impossible objects by relying on information

High-frequency welding trials.

PubMed

Kelch, R

2000-09-01

The high-frequency weldability of a new family of polyolefin films is compared with that of conventional films made of other polymers. A comparison of the optimum weld parameters of all the films and the results of performance testing of all the pouches produced are reported.

Examination of the high-frequency capability of carbon nanotube FETs

NASA Astrophysics Data System (ADS)

Pulfrey, David L.; Chen, Li

2008-09-01

New results are added to a recent critique of the high-frequency performance of carbon nanotube field-effect transistors (CNFETs). On the practical side, reduction of the number of metallic tubes in CNFETs fashioned from multiple nanotubes has allowed the measured fT to be increased to 30 GHz. On the theoretical side, the opinion that the band-structure-determined velocity limits the high-frequency performance has been reinforced by corrections to recent simulation results for doped-contact CNFETs, and by the ruling out of the possibility of favourable image-charge effects. Inclusion in the simulations of the features of finite gate-metal thickness and source/drain contact resistance has given an indication of likely practical values for fT. A meaningful comparison between CNFETs with doped-contacts and metallic contacts has been made.

Influence of gate overlap engineering on ambipolar and high frequency characteristics of tunnel-CNTFET

NASA Astrophysics Data System (ADS)

Shaker, Ahmed; Ossaimee, Mahmoud; Zekry, A.; Abouelatta, Mohamed

2015-10-01

In this paper, we have investigated the effect of gate overlapping-on-drain on the ambipolar behavior and high frequency performance of tunnel CNTFET (T-CNTFET). It is found that gate overlapping-on-drain suppresses the ambipolar behavior and improves OFF-state current. The simulation results show that there is an optimum choice for the overlapped length. On the other hand, this overlap deteriorates the high frequency performance. The high frequency figure of merit is analyzed in terms of the unit-gain cutoff frequency (fT). Further, we propose two different approaches to improve the high frequency performance of the overlapped T-CNTFET. The first one is based on inserting a high-dielectric constant material below the overlapped part of the gate and the second is based on depositing a different work function gate metal for the overlapped region. The two solutions show very good improvement in the high frequency performance with maintaining the suppression of the ambipolar characteristics.

Detection beyond the Debye screening length in a high-frequency nanoelectronic biosensor.

PubMed

Kulkarni, Girish S; Zhong, Zhaohui

2012-02-08

Nanosensors based on the unique electronic properties of nanotubes and nanowires offer high sensitivity and have the potential to revolutionize the field of Point-of-Care (POC) medical diagnosis. The direct current (dc) detection of a wide array of organic and inorganic molecules has been demonstrated on these devices. However, sensing mechanism based on measuring changes in dc conductance fails at high background salt concentrations, where the sensitivity of the devices suffers from the ionic screening due to mobile ions present in the solution. Here, we successfully demonstrate that the fundamental ionic screening effect can be mitigated by operating single-walled carbon nanotube field effect transistor as a high-frequency biosensor. The nonlinear mixing between the alternating current excitation field and the molecular dipole field can generate mixing current sensitive to the surface-bound biomolecules. Electrical detection of monolayer streptavidin binding to biotin in 100 mM buffer solution is achieved at a frequency beyond 1 MHz. Theoretical modeling confirms improved sensitivity at high frequency through mitigation of the ionic screening effect. The results should promise a new biosensing platform for POC detection, where biosensors functioning directly in physiologically relevant condition are desired. © 2012 American Chemical Society

Determining the frequency, depth and velocity of preferential flow by high frequency soil moisture monitoring

NASA Astrophysics Data System (ADS)

Hardie, Marcus; Lisson, Shaun; Doyle, Richard; Cotching, William

2013-01-01

Preferential flow in agricultural soils has been demonstrated to result in agrochemical mobilisation to shallow ground water. Land managers and environmental regulators need simple cost effective techniques for identifying soil - land use combinations in which preferential flow occurs. Existing techniques for identifying preferential flow have a range of limitations including; often being destructive, non in situ, small sampling volumes, or are subject to artificial boundary conditions. This study demonstrated that high frequency soil moisture monitoring using a multi-sensory capacitance probe mounted within a vertically rammed access tube, was able to determine the occurrence, depth, and wetting front velocity of preferential flow events following rainfall. Occurrence of preferential flow was not related to either rainfall intensity or rainfall amount, rather preferential flow occurred when antecedent soil moisture content was below 226 mm soil moisture storage (0-70 cm). Results indicate that high temporal frequency soil moisture monitoring may be used to identify soil type - land use combinations in which the presence of preferential flow increases the risk of shallow groundwater contamination by rapid transport of agrochemicals through the soil profile. However use of high frequency based soil moisture monitoring to determine agrochemical mobilisation risk may be limited by, inability to determine the volume of preferential flow, difficulty observing macropore flow at high antecedent soil moisture content, and creation of artificial voids during installation of access tubes in stony soils.

Evidence in Favor of the Early-Phase Elevated-Attention Hypothesis: The Effects of Letter Frequency and Object Frequency

ERIC Educational Resources Information Center

Criss, Amy H.; Malmberg, Kenneth J.

2008-01-01

One of the most studied and least well understood phenomena in episodic memory is the word frequency effect (WFE). The WFE is expressed as a mirror pattern where uncommon low frequency words (LF) are better recognized than common high frequency words (HF) by way of a higher HR and lower FAR. One explanation for the HR difference is the early-phase…

Development of miniature, high frequency pulse tube cryocoolers

NASA Astrophysics Data System (ADS)

Radebaugh, Ray; Garaway, Isaac; Veprik, Alexander M.

2010-04-01

Because acoustic power density is proportional to frequency, the size of pulse tube cryocoolers for a given refrigeration power can be reduced by operating them at higher frequencies. A frequency of about 60 Hz had been considered the maximum frequency that could be used while maintaining high efficiency. Recently, we have shown through modeling that by decreasing the volume and hydraulic diameter of the regenerator and increasing the average pressure, it is possible to maintain high efficiency even for frequencies of several hundred hertz. Subsequent experimental results have demonstrated high efficiencies for frequencies of 100 to 140 Hz. The very high power density achieved at higher pressures and higher frequencies leads to very short cooldown times and very compact devices. The use of even higher frequencies requires the development of special compressors designed for such conditions and the development of regenerator matrices with hydraulic diameters less than about 30 Μm. To demonstrate the advantages of higher frequency operation, we discuss here the development of a miniature pulse tube cryocooler designed to operate at 80 K with a frequency of 150 Hz and an average pressure of 5.0 MPa. The regenerator diameter and length are 4.4 mm and 27 mm, respectively. The lowest temperature achieved to date has been 97 K, but a net refrigeration power of 530 mW was achieved at 120 K. Acoustic mismatches with existing compressors significantly limit the efficiency, but necessary modifications to improve the acoustic impedance match between the compressor and the cold head are discussed briefly.

Solving the Capacitive Effect in the High-Frequency sweep for Langmuir Probe in SYMPLE

NASA Astrophysics Data System (ADS)

Pramila; Patel, J. J.; Rajpal, R.; Hansalia, C. J.; Anitha, V. P.; Sathyanarayana, K.

2017-04-01

Langmuir Probe based measurements need to be routinely carried out to measure various plasma parameters such as the electron density (ne), the electron temperature (Te), the floating potential (Vf), and the plasma potential (Vp). For this, the diagnostic electronics along with the biasing power supplies is installed in standard industrial racks with a 2KV isolation transformer. The Signal Conditioning Electronics (SCE) system is populated inside the 4U-chassis based system with the front-end electronics, designed using high common mode differential amplifiers which can measure small differential signal in presence of high common mode dc- bias or ac ramp voltage used for biasing the probes. DC-biasing of the probe is most common method for getting its I-V characteristic but method of biasing the probe with a sweep at high frequency encounters the problem of corruption of signal due to capacitive effect specially when the sweep period and the discharge time is very fast and die down in the order of μs or lesser. This paper presents and summarises the method of removing such effects encountered while measuring the probe current.

Monitoring of corrosion damage using high-frequency guided ultrasonic waves

NASA Astrophysics Data System (ADS)

Chew, D.; Fromme, P.

2014-03-01

Due to adverse environmental conditions corrosion can develop during the life cycle of industrial structures, e.g., offshore oil platforms, ships, and desalination plants. Both pitting corrosion and generalized corrosion leading to wall thickness loss can cause the degradation of the integrity and load bearing capacity of the structure. Structural health monitoring of corrosion damage in difficult to access areas can in principle be achieved using high frequency guided waves propagating along the structure from accessible areas. Using standard ultrasonic transducers with single sided access to the structure, high frequency guided wave modes were generated that penetrate through the complete thickness of the structure. Wall thickness reduction was induced using accelerated corrosion in a salt water bath. The corrosion damage was monitored based on the effect on the wave propagation and interference of the different modes. The change in the wave interference was quantified based on an analysis in the frequency domain (Fourier transform) and was found to match well with theoretical predictions for the wall thickness loss. High frequency guided waves have the potential for corrosion damage monitoring at critical and difficult to access locations from a stand-off distance.

Monitoring of corrosion damage using high-frequency guided ultrasonic waves

NASA Astrophysics Data System (ADS)

Chew, D.; Fromme, P.

2015-03-01

Due to adverse environmental conditions corrosion can develop during the life cycle of industrial structures, e.g., offshore oil platforms, ships, and desalination plants. Both pitting corrosion and generalized corrosion leading to wall thickness loss can cause the degradation of the integrity and load bearing capacity of the structure. Structural health monitoring of corrosion damage in difficult to access areas can in principle be achieved using high frequency guided waves propagating along the structure from accessible areas. Using standard ultrasonic transducers with single sided access to the structure, high frequency guided wave modes were generated that penetrate through the complete thickness of the structure. Wall thickness reduction was induced using accelerated corrosion in a salt water bath. The corrosion damage was monitored based on the effect on the wave propagation and interference of the different modes. The change in the wave interference was quantified based on an analysis in the frequency domain (Fourier transform) and was found to match well with theoretical predictions for the wall thickness loss. High frequency guided waves have the potential for corrosion damage monitoring at critical and difficult to access locations from a stand-off distance.

High-frequency resonant-tunneling oscillators

NASA Technical Reports Server (NTRS)

Brown, E. R.; Parker, C. D.; Calawa, A. R.; Manfra, M. J.; Chen, C. L.

1991-01-01

Advances in high-frequency resonant-tunneling-diode (RTD) oscillators are described. Oscillations up to a frequency of 420 GHz have been achieved in the GaAs/AlAs system. Recent results obtained with In0.53Ga0.47As/AlAs and InAs/AlSb RTDs show a greatly increased power density and indicate the potential for fundamental oscillations up to about 1 THz. These results are consistent with a lumped-element equivalent circuit model of the RTD. The model shows that the maximum oscillation frequency of the GaAs/AlAs RTDs is limited primarily by series resistance, and that the power density is limited by low peak-to-valley current ratio.

GaN transistors on Si for switching and high-frequency applications

NASA Astrophysics Data System (ADS)

Ueda, Tetsuzo; Ishida, Masahiro; Tanaka, Tsuyoshi; Ueda, Daisuke

2014-10-01

In this paper, recent advances of GaN transistors on Si for switching and high-frequency applications are reviewed. Novel epitaxial structures including superlattice interlayers grown by metal organic chemical vapor deposition (MOCVD) relieve the strain and eliminate the cracks in the GaN over large-diameter Si substrates up to 8 in. As a new device structure for high-power switching application, Gate Injection Transistors (GITs) with a p-AlGaN gate over an AlGaN/GaN heterostructure successfully achieve normally-off operations maintaining high drain currents and low on-state resistances. Note that the GITs on Si are free from current collapse up to 600 V, by which the drain current would be markedly reduced after the application of high drain voltages. Highly efficient operations of an inverter and DC-DC converters are presented as promising applications of GITs for power switching. The high efficiencies in an inverter, a resonant LLC converter, and a point-of-load (POL) converter demonstrate the superior potential of the GaN transistors on Si. As for high-frequency transistors, AlGaN/GaN heterojuction field-effect transistors (HFETs) on Si designed specifically for microwave and millimeter-wave frequencies demonstrate a sufficiently high output power at these frequencies. Output powers of 203 W at 2.5 GHz and 10.7 W at 26.5 GHz are achieved by the fabricated GaN transistors. These devices for switching and high-frequency applications are very promising as future energy-efficient electronics because of their inherent low fabrication cost and superior device performance.

Microscopic gate-modulation imaging of charge and field distribution in polycrystalline organic transistors

NASA Astrophysics Data System (ADS)

Matsuoka, Satoshi; Tsutsumi, Jun'ya; Kamata, Toshihide; Hasegawa, Tatsuo

2018-04-01

In this work, a high-resolution microscopic gate-modulation imaging (μ-GMI) technique is successfully developed to visualize inhomogeneous charge and electric field distributions in operating organic thin-film transistors (TFTs). We conduct highly sensitive and diffraction-limit gate-modulation sensing for acquiring difference images of semiconducting channels between at gate-on and gate-off states that are biased at an alternate frequency of 15 Hz. As a result, we observe unexpectedly inhomogeneous distribution of positive and negative local gate-modulation (GM) signals at a probe photon energy of 1.85 eV in polycrystalline pentacene TFTs. Spectroscopic analyses based on a series of μ-GMI at various photon energies reveal that two distinct effects appear, simultaneously, within the polycrystalline pentacene channel layers: Negative GM signals at 1.85 eV originate from the second-derivative-like GM spectrum which is caused by the effect of charge accumulation, whereas positive GM signals originate from the first-derivative-like GM spectrum caused by the effect of leaked gate fields. Comparisons with polycrystalline morphologies indicate that grain centers are predominated by areas with high leaked gate fields due to the low charge density, whereas grain edges are predominantly high-charge-density areas with a certain spatial extension as associated with the concentrated carrier traps. Consequently, it is reasonably understood that larger grains lead to higher device mobility, but with greater inhomogeneity in charge distribution. These findings provide a clue to understand and improve device characteristics of polycrystalline TFTs.

High-frequency plasma-heating apparatus

DOEpatents

Brambilla, Marco; Lallia, Pascal

1978-01-01

An array of adjacent wave guides feed high-frequency energy into a vacuum chamber in which a toroidal plasma is confined by a magnetic field, the wave guide array being located between two toroidal current windings. Waves are excited in the wave guide at a frequency substantially equal to the lower frequency hybrid wave of the plasma and a substantially equal phase shift is provided from one guide to the next between the waves therein. For plasmas of low peripheral density gradient, the guides are excited in the TE.sub.01 mode and the output electric field is parallel to the direction of the toroidal magnetic field. For exciting waves in plasmas of high peripheral density gradient, the guides are excited in the TM.sub.01 mode and the magnetic field at the wave guide outlets is parallel to the direction of the toroidal magnetic field. The wave excited at the outlet of the wave guide array is a progressive wave propagating in the direction opposite to that of the toroidal current and is, therefore, not absorbed by so-called "runaway" electrons.

Mechanisms of high-frequency song generation in brachypterous crickets and the role of ghost frequencies.

PubMed

Robillard, Tony; Montealegre-Z, Fernando; Desutter-Grandcolas, Laure; Grandcolas, Philippe; Robert, Daniel

2013-06-01

Sound production in crickets relies on stridulation, the well-understood rubbing together of a pair of specialised wings. As the file of one wing slides over the scraper of the other, a series of rhythmic impacts causes harmonic oscillations, usually resulting in the radiation of pure tones delivered at low frequencies (2-8 kHz). In the short-winged crickets of the Lebinthini tribe, acoustic communication relies on signals with remarkably high frequencies (>8 kHz) and rich harmonic content. Using several species of the subfamily Eneopterinae, we characterised the morphological and mechanical specialisations supporting the production of high frequencies, and demonstrated that higher harmonics are exploited as dominant frequencies. These specialisations affect the structure of the stridulatory file, the motor control of stridulation and the resonance of the sound radiator. We placed these specialisations in a phylogenetic framework and show that they serve to exploit high-frequency vibrational modes pre-existing in the phylogenetic ancestor. In Eneopterinae, the lower frequency components are harmonically related to the dominant peak, suggesting they are relicts of ancestral carrier frequencies. Yet, such ghost frequencies still occur in the wings' free resonances, highlighting the fundamental mechanical constraints of sound radiation. These results support the hypothesis that such high-frequency songs evolved stepwise, by a form of punctuated evolution that could be related to functional constraints, rather than by only the progressive increase of the ancestral fundamental frequency.

High efficiency quantum cascade laser frequency comb.

PubMed

Lu, Quanyong; Wu, Donghai; Slivken, Steven; Razeghi, Manijeh

2017-03-06

An efficient mid-infrared frequency comb source is of great interest to high speed, high resolution spectroscopy and metrology. Here we demonstrate a mid-IR quantum cascade laser frequency comb with a high power output and narrow beatnote linewidth at room temperature. The active region was designed with a strong-coupling between the injector and the upper lasing level for high internal quantum efficiency and a broadband gain. The group velocity dispersion was engineered for efficient, broadband mode-locking via four wave mixing. The comb device exhibits a narrow intermode beatnote linewidth of 50.5 Hz and a maximum wall-plug efficiency of 6.5% covering a spectral coverage of 110 cm -1 at λ ~ 8 μm. The efficiency is improved by a factor of 6 compared with previous demonstrations. The high power efficiency and narrow beatnote linewidth will greatly expand the applications of quantum cascade laser frequency combs including high-precision remote sensing and spectroscopy.

High efficiency quantum cascade laser frequency comb

PubMed Central

Lu, Quanyong; Wu, Donghai; Slivken, Steven; Razeghi, Manijeh

2017-01-01

An efficient mid-infrared frequency comb source is of great interest to high speed, high resolution spectroscopy and metrology. Here we demonstrate a mid-IR quantum cascade laser frequency comb with a high power output and narrow beatnote linewidth at room temperature. The active region was designed with a strong-coupling between the injector and the upper lasing level for high internal quantum efficiency and a broadband gain. The group velocity dispersion was engineered for efficient, broadband mode-locking via four wave mixing. The comb device exhibits a narrow intermode beatnote linewidth of 50.5 Hz and a maximum wall-plug efficiency of 6.5% covering a spectral coverage of 110 cm−1 at λ ~ 8 μm. The efficiency is improved by a factor of 6 compared with previous demonstrations. The high power efficiency and narrow beatnote linewidth will greatly expand the applications of quantum cascade laser frequency combs including high-precision remote sensing and spectroscopy. PMID:28262834

Effects of noise frequency on performance and annoyance for women and men

NASA Technical Reports Server (NTRS)

Key, K. F.; Payne, M. C., Jr.

1981-01-01

Effects of noise frequencies on both performance on a complex psychomotor task and annoyance were investigated for men (n = 30) and women (n = 30). Each subject performed a complex psychomotor task for 50 min in the presence of low-frequency noise, high-frequency noise, or ambient noise. Women and men learned the task at different rates. Little effect of noise was shown. Annoyance ratings were subsequently obtained from each subject for noises of various frequencies by the method of magnitude estimation. High-frequency noises were more annoying than low-frequency noises regardless of sex and immediate prior exposure to noise. Sex differences in annoyance did not occur. No direct relationship between learning to perform a complex task while exposed to noise and annoyance by that noise was demonstrated.

Broadband linear high-voltage amplifier for radio frequency ion traps.

PubMed

Kuhlicke, Alexander; Palis, Klaus; Benson, Oliver

2014-11-01

We developed a linear high-voltage amplifier for small capacitive loads consisting of a high-voltage power supply and a transistor amplifier. With this cost-effective circuit including only standard parts sinusoidal signals with a few volts can be amplified to 1.7 kVpp over a usable frequency range at large-signal response spanning four orders of magnitude from 20 Hz to 100 kHz under a load of 10 pF. For smaller output voltages the maximum frequency shifts up to megahertz. We test different capacitive loads to probe the influence on the performance. The presented amplifier is sustained short-circuit proof on the output side, which is a significant advantage over other amplifier concepts. The amplifier can be used to drive radio frequency ion traps for single charged nano- and microparticles, which will be presented in brief.

Effectiveness of the graded motor imagery to improve hand function in patients with distal radius fracture: A randomized controlled trial.

PubMed

Dilek, Burcu; Ayhan, Cigdem; Yagci, Gozde; Yakut, Yavuz

Single-blinded randomized controlled trial. Pain management is essential in the early stages of the rehabilitation of distal radius fractures (DRFx). Pain intensity at the acute stage is considered important for determining the individual recovery process, given that higher pain intensity and persistent pain duration negatively affect the function and cortical activity of pain response. Graded motor imagery (GMI) and its components are recent pain management strategies, established on a neuroscience basis. To investigate the effectiveness of GMI in hand function in patients with DRFx. Thirty-six participants were randomly allocated to either GMI (n = 17; 52.59 [9.8] years) or control (n = 19; 47.16 [10.5] years) groups. The GMI group received imagery treatment in addition to traditional rehabilitation, and the control group received traditional rehabilitation for 8 weeks. The assessments included pain at rest and during activity using the visual analog scale, wrist and forearm active range of motion (ROM) with universal goniometer, grip strength with the hydraulic dynamometer (Jamar; Bolingbrook, IL), and upper extremity functional status using the Disability of the Arm, Shoulder and Hand Questionnaire, and the Michigan Hand Questionnaire. Assessments were performed twice at baseline and at the end of the eighth week. The GMI group showed greater improvement in pain intensity (during rest, 2.24; activity, 6.18 points), wrist ROM (flexion, -40.59; extension, -45.59; radial deviation, -25.59; and ulnar deviation, -26.77 points) and forearm ROM (supination, -43.82 points), and functional status (Disability of the Arm, Shoulder and Hand Questionnaire, 38.00; Michigan Hand Questionnaire, -32.53 points) when compared with the control group (for all, P < .05). The cortical model of pathological pain suggests new strategies established on a neuroscience basis. These strategies aim to normalize the cortical proprioceptive representation and reduce pain. One of

Chinchilla middle-ear admittance and sound power: High-frequency estimates and effects of inner-ear modifications

PubMed Central

Ravicz, Michael E.; Rosowski, John J.

2012-01-01

The middle-ear input admittance relates sound power into the middle ear (ME) and sound pressure at the tympanic membrane (TM). ME input admittance was measured in the chinchilla ear canal as part of a larger study of sound power transmission through the ME into the inner ear. The middle ear was open, and the inner ear was intact or modified with small sensors inserted into the vestibule near the cochlear base. A simple model of the chinchilla ear canal, based on ear canal sound pressure measurements at two points along the canal and an assumption of plane-wave propagation, enables reliable estimates of YTM, the ME input admittance at the TM, from the admittance measured relatively far from the TM. YTM appears valid at frequencies as high as 17 kHz, a much higher frequency than previously reported. The real part of YTM decreases with frequency above 2 kHz. Effects of the inner-ear sensors (necessary for inner ear power computation) were small and generally limited to frequencies below 3 kHz. Computed power reflectance was ∼0.1 below 3.5 kHz, lower than with an intact ME below 2.5 kHz, and nearly 1 above 16 kHz. PMID:23039439

High-frequency matrix converter with square wave input

DOEpatents

Carr, Joseph Alexander; Balda, Juan Carlos

2015-03-31

A device for producing an alternating current output voltage from a high-frequency, square-wave input voltage comprising, high-frequency, square-wave input a matrix converter and a control system. The matrix converter comprises a plurality of electrical switches. The high-frequency input and the matrix converter are electrically connected to each other. The control system is connected to each switch of the matrix converter. The control system is electrically connected to the input of the matrix converter. The control system is configured to operate each electrical switch of the matrix converter converting a high-frequency, square-wave input voltage across the first input port of the matrix converter and the second input port of the matrix converter to an alternating current output voltage at the output of the matrix converter.

Antimicrobial Effect of Ozone Made by KP Syringe of High-Frequency Ozone Generator

PubMed Central

Prebeg, Domagoj; Katunarić, Marina; Budimir, Ana; Šegović, Sanja; Anić, Ivica

2016-01-01

Aim The aim of this study was to evaluate in vitro the antibacterial effect of ozone on suspension of three different bacteria inoculated in prepared canals of extracted human teeth. Material and methods Ozone was produced by special KP syringe of high frequency ozone generator Ozonytron (Biozonix, München, Germany) from aspirated atmospheric air by dielectric barrier discharge and applied through the tip of the syringe to the prepared root canal. The microorganisms used were Enterococcus faecalis, Staphylococcus aureus and Staphylococcus epidermidis. Results However, none of the methods was 100% effective against the three bacterial types in suspension. Application of ozone significantly decreased the absolute count of microorganisms (89.3%), as well as the count of each type of bacteria separately (Staphylococcus aureus 94.0%; Staphylococcus epidermidis 88.6% and Enterococcus faecalis 79.7%). Ozone generated by KP syringe was statistically more effective compared to NaOCl as positive control, for Staphylococcus aureus and Staphylococcus epidermidis. Conclusion The absolute count of Enterococcus faecalis was statistically decreased without a statistically significant difference between the tested group and positive control, respectively. Among the three types of bacteria in suspension, KP probe had the lowest antimicrobial effect against Enterococcus faecalis. PMID:27789911

[Comparative evaluation of the efficiency of the effect of very high frequency electromagnetic waves on platelet functional activity].

PubMed

Kirichuk, V F; Maĭborodin, A V; Volin, M V; Krenitskiĭ, A P; Tupikin, V D

2001-01-01

A comparative analysis was made of the effect of two kinds of EMI MMD-radiation: EMI MMD-waves, generated by a vehicle "Jav-1 M" (42.2 and 53.5 HHz), and EMI MMD-waves exerting influence with frequencies of molecular spectrum of radiation and nitric oxide absorption (150.176-150.644 HHz), obtained with a specially created generator, with respect to their influence on the functional ability of platelets of unstable angina pectoris patients. It was shown that in vitro EMI MMD-fluctuations with frequencies of molecular spectrum of radiation and nitric oxide absorption exert a stronger inhibiting influence on the functional activity of platelets of unstable angina pectoris patients. Features of the action of various kinds of EMI MMD-effect on the activative-high-speed characteristics of platelet aggregation are shown.

Preliminary Evidence of the Effects of High-frequency Repetitive Transcranial Magnetic Stimulation (rTMS) on Swallowing Functions in Post-Stroke Individuals with Chronic Dysphagia

ERIC Educational Resources Information Center

Cheng, Ivy K. Y.; Chan, Karen M. K.; Wong, C. S.; Cheung, Raymond T. F.

2015-01-01

Background: There is growing evidence of potential benefits of repetitive transcranial magnetic stimulation (rTMS) in the rehabilitation of dysphagia. However, the site and frequency of stimulation for optimal effects are not clear. Aims: The aim of this pilot study is to investigate the short-term effects of high-frequency 5 Hz rTMS applied to…

Word frequency influences on the list length effect and associative memory in young and older adults.

PubMed

Badham, Stephen P; Whitney, Cora; Sanghera, Sumeet; Maylor, Elizabeth A

2017-07-01

Many studies show that age deficits in memory are smaller for information supported by pre-experimental experience. Many studies also find dissociations in memory tasks between words that occur with high and low frequencies in language, but the literature is mixed regarding the extent of word frequency effects in normal ageing. We examined whether age deficits in episodic memory could be influenced by manipulations of word frequency. In Experiment 1, young and older adults studied short and long lists of high- and low-frequency words for free recall. The list length effect (the drop in proportion recalled for longer lists) was larger in young compared to older adults and for high- compared to low-frequency words. In Experiment 2, young and older adults completed item and associative recognition memory tests with high- and low-frequency words. Age deficits were greater for associative memory than for item memory, demonstrating an age-related associative deficit. High-frequency words led to better associative memory performance whilst low-frequency words resulted in better item memory performance. In neither experiment was there any evidence for age deficits to be smaller for high- relative to low-frequency words, suggesting that word frequency effects on memory operate independently from effects due to cognitive ageing.

A MEMS-based high frequency x-ray chopper.

PubMed

Siria, A; Dhez, O; Schwartz, W; Torricelli, G; Comin, F; Chevrier, J

2009-04-29

Time-resolved x-ray experiments require intensity modulation at high frequencies (advanced rotating choppers have nowadays reached the kHz range). We here demonstrate that a silicon microlever oscillating at 13 kHz with nanometric amplitude can be used as a high frequency x-ray chopper. We claim that using micro-and nanoelectromechanical systems (MEMS and NEMS), it will be possible to achieve higher frequencies in excess of hundreds of megahertz. Working at such a frequency can open a wealth of possibilities in chemistry, biology and physics time-resolved experiments.

Histologic effects of different technologies for dissection in endoscopic surgery: Nd:YAG laser, high frequency and water-jet.

PubMed

Schurr, M O; Wehrmann, M; Kunert, W; Melzer, A; Lirici, M M; Trapp, R; Kanehira, E; Buess, G

1994-01-01

Precise cutting combined with reliable coagulation of the margins of the lesion is an important requirement for dissection techniques in endoscopic surgery. These requirements are met by the two most common ancillary energy sources applied for endoscopic dissection today, electrosurgery and "thermal lasers", mostly the Nd:YAG. For the comparison of the histological effects of monopolar and bipolar high frequency with the Nd:YAG laser an experimental in vitro and in vivo study has been performed. In order to evaluate the advantages of non thermal dissection for endoscopic procedures, a water jet cutting system was included in the in vitro study. In parenchymatous tissue the water jet was found to be the least traumatic technique, followed by bipolar high frequency, laser and monopolar high frequency. The water jet was not applicable for intestinal dissection since uncontrolled bloating of the rectal wall with uncontrolled disruption of the tissue layers occurred. A general disadvantage is that secure haemostasis in the line of incision is hard to achieve. In the microscopic comparison of the shape of the incision, the Nd:YAG laser produced the smoothest lesions with well-defined margins. The monopolar technique was more often associated with irregular and sometimes fissured margins. These results were confirmed in the in vivo part of the study (Transanal Endoscopic Microsurgery).

Impact of high-frequency pumping on anomalous finite-size effects in three-dimensional topological insulators

NASA Astrophysics Data System (ADS)

Pervishko, Anastasiia A.; Yudin, Dmitry; Shelykh, Ivan A.

2018-02-01

Lowering of the thickness of a thin-film three-dimensional topological insulator down to a few nanometers results in the gap opening in the spectrum of topologically protected two-dimensional surface states. This phenomenon, which is referred to as the anomalous finite-size effect, originates from hybridization between the states propagating along the opposite boundaries. In this work, we consider a bismuth-based topological insulator and show how the coupling to an intense high-frequency linearly polarized pumping can further be used to manipulate the value of a gap. We address this effect within recently proposed Brillouin-Wigner perturbation theory that allows us to map a time-dependent problem into a stationary one. Our analysis reveals that both the gap and the components of the group velocity of the surface states can be tuned in a controllable fashion by adjusting the intensity of the driving field within an experimentally accessible range and demonstrate the effect of light-induced band inversion in the spectrum of the surface states for high enough values of the pump.

Frequency difference limens at high frequencies: evidence for a transition from a temporal to a place code.

PubMed

Moore, Brian C J; Ernst, Stephan M A

2012-09-01

It is commonly believed that difference limens for frequency (DLFs) for pure tones depend on a temporal mechanism (phase locking) for frequencies up to 4-5 kHz and a place mechanism at higher frequencies. The DLFs predicted from a place mechanism, expressed as a proportion of center frequency (Δf/f), should be approximately invariant with frequency at medium to high frequencies. If there is a transition from a temporal to a place mechanism, Δf/f should increase with increasing center frequency until the transition occurs, and then reach a plateau. Published data do not show such an effect. In this study, DLFs were measured for center frequencies from 2 to 14 kHz, using earphones designed to produce a flat response at the eardrum. The level of every tone was varied over a range of ±4 dB, to reduce loudness cues. The value of Δf/f increased progressively from 2 to 8 kHz, but did not change significantly for frequencies from 8 to 14 kHz. The results are consistent with the idea that there is a transition from a temporal to a place mechanism at about 8 kHz, rather than at 4-5 kHz, as is commonly assumed.

Diurnal Variation of Tropical Ice Cloud Microphysics: Evidence from Global Precipitation Measurement Microwave Imager Polarimetric Measurements

NASA Astrophysics Data System (ADS)

Gong, Jie; Zeng, Xiping; Wu, Dong L.; Li, Xiaowen

2018-01-01

The diurnal variation of tropical ice clouds has been well observed and examined in terms of the occurring frequency and total mass but rarely from the viewpoint of ice microphysical parameters. It accounts for a large portion of uncertainties in evaluating ice clouds' role on global radiation and hydrological budgets. Owing to the advantage of precession orbit design and paired polarized observations at a high-frequency microwave band that is particularly sensitive to ice particle microphysical properties, 3 years of polarimetric difference (PD) measurements using the 166 GHz channel of Global Precipitation Measurement Microwave Imager (GPM-GMI) are compiled to reveal a strong diurnal cycle over tropical land (30°S-30°N) with peak amplitude varying up to 38%. Since the PD signal is dominantly determined by ice crystal size, shape, and orientation, the diurnal cycle observed by GMI can be used to infer changes in ice crystal properties. Moreover, PD change is found to lead the diurnal changes of ice cloud occurring frequency and total ice mass by about 2 h, which strongly implies that understanding ice microphysics is critical to predict, infer, and model ice cloud evolution and precipitation processes.

Dynamic properties of ionospheric plasma turbulence driven by high-power high-frequency radiowaves

NASA Astrophysics Data System (ADS)

Grach, S. M.; Sergeev, E. N.; Mishin, E. V.; Shindin, A. V.

2016-11-01

A review is given of the current state-of-the-art of experimental studies and the theoretical understanding of nonlinear phenomena that occur in the ionospheric F-layer irradiated by high-power high-frequency ground-based transmitters. The main focus is on the dynamic features of high-frequency turbulence (plasma waves) and low-frequency turbulence (density irregularities of various scales) that have been studied in experiments at the Sura and HAARP heating facilities operated in temporal and frequency regimes specially designed with consideration of the characteristic properties of nonlinear processes in the perturbed ionosphere using modern radio receivers and optical instruments. Experimental results are compared with theoretical turbulence models for a magnetized collisional plasma in a high-frequency electromagnetic field, allowing the identification of the processes responsible for the observed features of artificial ionospheric turbulence.

High-power radio-frequency attenuation device

DOEpatents

Kerns, Q.A.; Miller, H.W.

1981-12-30

A resistor device for attenuating radio frequency power includes a radio frequency conductor connected to a series of fins formed of high relative magnetic permeability material. The fins are dimensional to accommodate the skin depth of the current conduction therethrough, as well as an inner heat conducting portion where current does not travel. Thermal connections for air or water cooling are provided for the inner heat conducting portions of each fin. Also disclosed is a resistor device to selectively alternate unwanted radio frequency energy in a resonant cavity.

High power radio frequency attenuation device

DOEpatents

Kerns, Quentin A.; Miller, Harold W.

1984-01-01

A resistor device for attenuating radio frequency power includes a radio frequency conductor connected to a series of fins formed of high relative magnetic permeability material. The fins are dimensional to accommodate the skin depth of the current conduction therethrough, as well as an inner heat conducting portion where current does not travel. Thermal connections for air or water cooling are provided for the inner heat conducting portions of each fin. Also disclosed is a resistor device to selectively alternate unwanted radio frequency energy in a resonant cavity.

Effectiveness of high-frequency transcutaneous electrical nerve stimulation at tender points as adjuvant therapy for patients with fibromyalgia.

PubMed

Carbonario, F; Matsutani, L A; Yuan, S L K; Marques, A P

2013-04-01

Fibromyalgia is a chronic pain syndrome associated with sleep disorders, fatigue and psychological symptoms. Combinations therapies, such as electrotherapy and therapeutic exercises have been used in the clinical practice. To assess the efficacy of high-frequency transcutaneous electrical nerve stimulation (TENS) as an adjuvant therapy to aerobic and stretching exercises, for the treatment of fibromyalgia. Controlled clinical trial. Unit of rehabilitation of a public hospital. Twenty-eight women aged 52.4±7.5 years, with fibromyalgia. A visual analogue scale measured pain intensity; tender points pain threshold, by dolorimetry; and quality of life, by the Fibromyalgia Impact Questionnaire. All subjects participated in an eight-week program consisting of aerobic exercises, followed by static stretching of muscle chains. In TENS group, high-frequency (150 Hz) was applied on bilateral tender points of trapezium and supraspinatus. TENS group had a greater pain reduction (mean change score=-2.0±2.9 cm) compared to Without TENS group (-0.7±3.7 cm). There was a difference between mean change scores of each group for pain threshold (right trapezium: 0.2±1 kg/cm² in TENS group and -0.2±1.2 kg/cm² in Without TENS group). In the evaluation of clinically important changes, patients receiving TENS had relevant improvement of pain, work performance, fatigue, stiffness, anxiety and depression compared to those not receiving TENS. It has suggested that high-frequency TENS as an adjuvant therapy is effective in relieving pain, anxiety, fatigue, stiffness, and in improving ability to work of patients with fibromyalgia. High-frequency TENS may be used as a short-term complementary treatment of fibromyalgia.

Analysis of high-frequency oscillations in mutually-coupled nano-lasers.

PubMed

Han, Hong; Shore, K Alan

2018-04-16

The dynamics of mutually coupled nano-lasers has been analyzed using rate equations which include the Purcell cavity-enhanced spontaneous emission factor F and the spontaneous emission coupling factor β. It is shown that in the mutually-coupled system, small-amplitude oscillations with frequencies of order 100 GHz are generated and are maintained with remarkable stability. The appearance of such high-frequency oscillations is associated with the effective reduction of the carrier lifetime for larger values of the Purcell factor, F, and spontaneous coupling factor, β. In mutually-coupled nano-lasers the oscillation frequency changes linearly with the frequency detuning between the lasers. For non-identical bias currents, the oscillation frequency of mutually-coupled nano-lasers also increases with bias current. The stability of the oscillations which appear in mutually coupled nano-lasers offers opportunities for their practical applications and notably in photonic integrated circuits.

Enhancing interaural-delay-based extents of laterality at high frequencies by using ``transposed stimuli''

NASA Astrophysics Data System (ADS)

Bernstein, Leslie R.; Trahiotis, Constantine

2003-06-01

An acoustic pointing task was used to determine whether interaural temporal disparities (ITDs) conveyed by high-frequency ``transposed'' stimuli would produce larger extents of laterality than ITDs conveyed by bands of high-frequency Gaussian noise. The envelopes of transposed stimuli are designed to provide high-frequency channels with information similar to that conveyed by the waveforms of low-frequency stimuli. Lateralization was measured for low-frequency Gaussian noises, the same noises transposed to 4 kHz, and high-frequency Gaussian bands of noise centered at 4 kHz. Extents of laterality obtained with the transposed stimuli were greater than those obtained with bands of Gaussian noise centered at 4 kHz and, in some cases, were equivalent to those obtained with low-frequency stimuli. In a second experiment, the general effects on lateral position produced by imposed combinations of bandwidth, ITD, and interaural phase disparities (IPDs) on low-frequency stimuli remained when those stimuli were transposed to 4 kHz. Overall, the data were fairly well accounted for by a model that computes the cross-correlation subsequent to known stages of peripheral auditory processing augmented by low-pass filtering of the envelopes within the high-frequency channels of each ear.

Behavioral in-effectiveness of high frequency electromagnetic field in mice.

PubMed

Salunke, Balwant P; Umathe, Sudhir N; Chavan, Jagatpalsingh G

2015-03-01

The present investigation was carried out with an objective to study the influence of high frequency electromagnetic field (HF-EMF) on anxiety, obsessive compulsive disorder (OCD) and depression-like behavior. For exposure to HF-EMF, non-magnetic material was used to fabricate the housing. Mice were exposed to HF-EMF (2.45GHz), 60min/day for 7 or 30 or 60 or 90 or 120days. The exposure was carried out by switching-on inbuilt class-I BLUETOOTH device that operates on 2.45GHz frequency in file transfer mode at a peak density of 100mW. Mice were subjected to the assessment of anxiety, OCD and depression-like behavior for 7 or 30 or 60 or 90 or 120days of exposure. The anxiety-like behavior was assessed by elevated plus maze, open field test and social interaction test. OCD-like behavior was assessed by marble burying behavior, whereas depression-like behavior was assessed by forced swim test and tail suspension test. The present experiment demonstrates that up to 120days of exposure to HF-EMF does not produce anxiety, OCD and depression-like behavior in mice. Copyright © 2014 Elsevier Inc. All rights reserved.

Error Analysis of Clay-Rock Water Content Estimation with Broadband High-Frequency Electromagnetic Sensors—Air Gap Effect

PubMed Central

Bore, Thierry; Wagner, Norman; Delepine Lesoille, Sylvie; Taillade, Frederic; Six, Gonzague; Daout, Franck; Placko, Dominique

2016-01-01

Broadband electromagnetic frequency or time domain sensor techniques present high potential for quantitative water content monitoring in porous media. Prior to in situ application, the impact of the relationship between the broadband electromagnetic properties of the porous material (clay-rock) and the water content on the frequency or time domain sensor response is required. For this purpose, dielectric properties of intact clay rock samples experimental determined in the frequency range from 1 MHz to 10 GHz were used as input data in 3-D numerical frequency domain finite element field calculations to model the one port broadband frequency or time domain transfer function for a three rods based sensor embedded in the clay-rock. The sensor response in terms of the reflection factor was analyzed in time domain with classical travel time analysis in combination with an empirical model according to Topp equation, as well as the theoretical Lichtenecker and Rother model (LRM) to estimate the volumetric water content. The mixture equation considering the appropriate porosity of the investigated material provide a practical and efficient approach for water content estimation based on classical travel time analysis with the onset-method. The inflection method is not recommended for water content estimation in electrical dispersive and absorptive material. Moreover, the results clearly indicate that effects due to coupling of the sensor to the material cannot be neglected. Coupling problems caused by an air gap lead to dramatic effects on water content estimation, even for submillimeter gaps. Thus, the quantitative determination of the in situ water content requires careful sensor installation in order to reach a perfect probe clay rock coupling. PMID:27096865

Error Analysis of Clay-Rock Water Content Estimation with Broadband High-Frequency Electromagnetic Sensors--Air Gap Effect.

PubMed

Bore, Thierry; Wagner, Norman; Lesoille, Sylvie Delepine; Taillade, Frederic; Six, Gonzague; Daout, Franck; Placko, Dominique

2016-04-18

Broadband electromagnetic frequency or time domain sensor techniques present high potential for quantitative water content monitoring in porous media. Prior to in situ application, the impact of the relationship between the broadband electromagnetic properties of the porous material (clay-rock) and the water content on the frequency or time domain sensor response is required. For this purpose, dielectric properties of intact clay rock samples experimental determined in the frequency range from 1 MHz to 10 GHz were used as input data in 3-D numerical frequency domain finite element field calculations to model the one port broadband frequency or time domain transfer function for a three rods based sensor embedded in the clay-rock. The sensor response in terms of the reflection factor was analyzed in time domain with classical travel time analysis in combination with an empirical model according to Topp equation, as well as the theoretical Lichtenecker and Rother model (LRM) to estimate the volumetric water content. The mixture equation considering the appropriate porosity of the investigated material provide a practical and efficient approach for water content estimation based on classical travel time analysis with the onset-method. The inflection method is not recommended for water content estimation in electrical dispersive and absorptive material. Moreover, the results clearly indicate that effects due to coupling of the sensor to the material cannot be neglected. Coupling problems caused by an air gap lead to dramatic effects on water content estimation, even for submillimeter gaps. Thus, the quantitative determination of the in situ water content requires careful sensor installation in order to reach a perfect probe clay rock coupling.

High-Frequency Subband Compressed Sensing MRI Using Quadruplet Sampling

PubMed Central

Sung, Kyunghyun; Hargreaves, Brian A

2013-01-01

Purpose To presents and validates a new method that formalizes a direct link between k-space and wavelet domains to apply separate undersampling and reconstruction for high- and low-spatial-frequency k-space data. Theory and Methods High- and low-spatial-frequency regions are defined in k-space based on the separation of wavelet subbands, and the conventional compressed sensing (CS) problem is transformed into one of localized k-space estimation. To better exploit wavelet-domain sparsity, CS can be used for high-spatial-frequency regions while parallel imaging can be used for low-spatial-frequency regions. Fourier undersampling is also customized to better accommodate each reconstruction method: random undersampling for CS and regular undersampling for parallel imaging. Results Examples using the proposed method demonstrate successful reconstruction of both low-spatial-frequency content and fine structures in high-resolution 3D breast imaging with a net acceleration of 11 to 12. Conclusion The proposed method improves the reconstruction accuracy of high-spatial-frequency signal content and avoids incoherent artifacts in low-spatial-frequency regions. This new formulation also reduces the reconstruction time due to the smaller problem size. PMID:23280540

Effect of High-Frequency Transcranial Magnetic Stimulation on Craving in Substance Use Disorder: A Meta-Analysis.

PubMed

Maiti, Rituparna; Mishra, Biswa Ranjan; Hota, Debasish

2017-01-01

Repetitive transcranial magnetic stimulation (rTMS), a noninvasive, neuromodulatory tool, has been used to reduce craving in different substance use disorders. There are some studies that have reported conflicting and inconclusive results; therefore, this meta-analysis was conducted to evaluate the effect of high-frequency rTMS on craving in substance use disorder and to investigate the reasons behind the inconsistency across the studies. The authors searched clinical trials from MEDLINE, Cochrane databases, and International Clinical Trials Registry Platform. The PRISMA guidelines, as well as recommended meta-analysis practices, were followed in the selection process, analysis, and reporting of the findings. The effect estimate used was the standardized mean difference (Hedge's g), and heterogeneity across the considered studies was explored using subgroup analyses. The quality assessment was done using the Cochrane risk of bias tool, and sensitivity analysis was performed to check the influences on effect size by statistical models. After screening and assessment of eligibility, finally 10 studies were included for meta-analysis, which includes six studies on alcohol and four studies on nicotine use disorder. The random-model analysis revealed a pooled effect size of 0.75 (95% CI=0.29 to 1.21, p=0.001), whereas the fixed-model analysis showed a large effect size of 0.87 (95% CI=0.63 to 1.12, p<0.00001). Subgroup analysis for alcohol use disorder showed an effect size of -0.06 (95% CI=-0.89 to 0.77, p=0.88). In the case of nicotine use disorder, random-model analysis revealed an effect size of 1.00 (95% CI=0.48 to 1.55, p=0.0001), whereas fixed-model analysis also showed a large effect size of 0.96 (95% CI=0.71 to 1.22). The present meta-analysis identified a beneficial effect of high-frequency rTMS on craving associated with nicotine use disorder but not alcohol use disorder.

Airway Humidification During High-Frequency Percussive Ventilation

DTIC Science & Technology

2009-03-01

Airway Humidification During High-Frequency Percussive Ventilation Patrick F Allan MD, Michael J Hollingsworth CRT, Gordon C Maniere CRT, Anthony K...about the risk of inadequate humidification during high- frequency percussive ventilation (HFPV). METHODS: We studied 5 humidifiers during HFPV with a...50 L/min, and the ConchaTherm Hi-Flow with VDR nebulizer) provided carinal humidification equivalent to the comparator setup, without regard to

Frequency-Temperature Compensation Techniques for High-Q Microwave Resonators

NASA Astrophysics Data System (ADS)

Hartnett, John G.; Tobar, Michael E.

Low-noise high-stability resonator oscillators based on high-Q monolithic sapphire ``Whispering Gallery'' (WG)-mode resonators have become important devices for telecommunication, radar and metrological applications. The extremely high quality factor of sapphire, of 2 x10^5 at room temperature, 5 x10^7 at liquid nitrogen temperature and 5 x10^9 at liquid helium temperature has enabled the lowest phase noise and highly frequency-stable oscillators in the microwave regime to be constructed. To create an oscillator with exceptional frequency stability, the resonator must have its frequency-temperature dependence annulled at some temperature, as well as a high quality factor. The Temperature Coefficient of Permittivity (TCP) for sapphire is quite large, at 10-100parts per million/K above 77K. This mechanism allows temperature fluctuations to transform to resonator frequency fluctuations.A number of research groups worldwide have investigated various methods of compensating the TCP of a sapphire dielectric resonator at different temperatures. The usual electromagnetic technique of annulment involves the use of paramagnetic impurities contributing an opposite temperature coefficient of the magnetic susceptibility to the TCP. This technique has only been realized successfully in liquid helium environments. Near 4K the thermal expansion and permittivity effects are small and only small quantities of the paramagnetic ions are necessary to compensate the mode frequency. Compensation is due to impurity ions that were incidentally left over from the manufacturing process.Recently, there has been an effort to dispense with the need for liquid helium and make a compact flywheel oscillator for the new generation of primary frequency standards such as the cesium fountain at the Laboratoire Primaire du Temps et des Fréquences (LPTF), France. To achieve the stability limit imposed

High-frequency and high-quality silicon carbide optomechanical microresonators

PubMed Central

Lu, Xiyuan; Lee, Jonathan Y.; Lin, Qiang

2015-01-01

Silicon carbide (SiC) exhibits excellent material properties attractive for broad applications. We demonstrate the first SiC optomechanical microresonators that integrate high mechanical frequency, high mechanical quality, and high optical quality into a single device. The radial-breathing mechanical mode has a mechanical frequency up to 1.69 GHz with a mechanical Q around 5500 in atmosphere, which corresponds to a fm · Qm product as high as 9.47 × 1012 Hz. The strong optomechanical coupling allows us to efficiently excite and probe the coherent mechanical oscillation by optical waves. The demonstrated devices, in combination with the superior thermal property, chemical inertness, and defect characteristics of SiC, show great potential for applications in metrology, sensing, and quantum photonics, particularly in harsh environments that are challenging for other device platforms. PMID:26585637

Effects of different frequencies of transcutaneous electrical nerve stimulation on venous vascular reactivity

PubMed Central

Franco, O.S.; Paulitsch, F.S.; Pereira, A.P.C.; Teixeira, A.O.; Martins, C.N.; Silva, A.M.V.; Plentz, R.D.M.; Irigoyen, M.C.; Signori, L.U.

2014-01-01

Transcutaneous electrical nerve stimulation (TENS) is a type of therapy used primarily for analgesia, but also presents changes in the cardiovascular system responses; its effects are dependent upon application parameters. Alterations to the cardiovascular system suggest that TENS may modify venous vascular response. The objective of this study was to evaluate the effects of TENS at different frequencies (10 and 100 Hz) on venous vascular reactivity in healthy subjects. Twenty-nine healthy male volunteers were randomized into three groups: placebo (n=10), low-frequency TENS (10 Hz, n=9) and high-frequency TENS (100 Hz, n=10). TENS was applied for 30 min in the nervous plexus trajectory from the superior member (from cervical to dorsal region of the fist) at low (10 Hz/200 μs) and high frequency (100 Hz/200 μs) with its intensity adjusted below the motor threshold and intensified every 5 min, intending to avoid accommodation. Venous vascular reactivity in response to phenylephrine, acetylcholine (endothelium-dependent) and sodium nitroprusside (endothelium-independent) was assessed by the dorsal hand vein technique. The phenylephrine effective dose to achieve 70% vasoconstriction was reduced 53% (P<0.01) using low-frequency TENS (10 Hz), while in high-frequency stimulation (100 Hz), a 47% increased dose was needed (P<0.01). The endothelium-dependent (acetylcholine) and independent (sodium nitroprusside) responses were not modified by TENS, which modifies venous responsiveness, and increases the low-frequency sensitivity of α1-adrenergic receptors and shows high-frequency opposite effects. These changes represent an important vascular effect caused by TENS with implications for hemodynamics, inflammation and analgesia. PMID:24820225

High power, high signal-to-noise ratio single-frequency 1μm Brillouin all-fiber laser

NASA Astrophysics Data System (ADS)

Wang, Jing; Hou, Yubin; Zhang, Qian; Jin, Dongchen; Sun, Ruoyu; Shi, Hongxing; Liu, Jiang; Wang, Pu

2016-03-01

We demonstrate a high-power, high signal-to-noise ratio single-frequency 1 μm Brillouin all-fiber laser with high slope efficiency. The Brillouin laser system consists of a high-power single-frequency fiber laser and a single-pass Brillouin ring cavity. The high-power single-frequency fiber laser is one-stage master-oscillator power amplifier with the maximum output power of 10.33 W, the signal-to-noise ratio of 50 dB and the slope efficiency of 46%. The Brillouin fiber laser is pumped by the amplified laser with a linewidth of 33 kHz and an output power of 2.61 W limited by the damage threshold of the optical isolator. By optimizing the length of the Brillouin ring cavity to 10 m, stable singlefrequency Brillouin fiber laser is obtained with 3 kHz linewidth owing to the linewidth narrowing effect. At the launched pump power of 2.15 W, the Brillouin fiber laser generates maximum output power of 1.4 W with a slope efficiency of 79% and the optical signal-to-noise ratio of 77 dB.

Asynchronous BCI control using high-frequency SSVEP.

PubMed

Diez, Pablo F; Mut, Vicente A; Avila Perona, Enrique M; Laciar Leber, Eric

2011-07-14

Steady-State Visual Evoked Potential (SSVEP) is a visual cortical response evoked by repetitive stimuli with a light source flickering at frequencies above 4 Hz and could be classified into three ranges: low (up to 12 Hz), medium (12-30) and high frequency (> 30 Hz). SSVEP-based Brain-Computer Interfaces (BCI) are principally focused on the low and medium range of frequencies whereas there are only a few projects in the high-frequency range. However, they only evaluate the performance of different methods to extract SSVEP. This research proposed a high-frequency SSVEP-based asynchronous BCI in order to control the navigation of a mobile object on the screen through a scenario and to reach its final destination. This could help impaired people to navigate a robotic wheelchair. There were three different scenarios with different difficulty levels (easy, medium and difficult). The signal processing method is based on Fourier transform and three EEG measurement channels. The research obtained accuracies ranging in classification from 65% to 100% with Information Transfer Rate varying from 9.4 to 45 bits/min. Our proposed method allows all subjects participating in the study to control the mobile object and to reach a final target without prior training.

Effective data validation of high-frequency data: time-point-, time-interval-, and trend-based methods.

PubMed

Horn, W; Miksch, S; Egghart, G; Popow, C; Paky, F

1997-09-01

Real-time systems for monitoring and therapy planning, which receive their data from on-line monitoring equipment and computer-based patient records, require reliable data. Data validation has to utilize and combine a set of fast methods to detect, eliminate, and repair faulty data, which may lead to life-threatening conclusions. The strength of data validation results from the combination of numerical and knowledge-based methods applied to both continuously-assessed high-frequency data and discontinuously-assessed data. Dealing with high-frequency data, examining single measurements is not sufficient. It is essential to take into account the behavior of parameters over time. We present time-point-, time-interval-, and trend-based methods for validation and repair. These are complemented by time-independent methods for determining an overall reliability of measurements. The data validation benefits from the temporal data-abstraction process, which provides automatically derived qualitative values and patterns. The temporal abstraction is oriented on a context-sensitive and expectation-guided principle. Additional knowledge derived from domain experts forms an essential part for all of these methods. The methods are applied in the field of artificial ventilation of newborn infants. Examples from the real-time monitoring and therapy-planning system VIE-VENT illustrate the usefulness and effectiveness of the methods.

Frequency Response of Graphene Electrolyte-Gated Field-Effect Transistors

PubMed Central

McVay, Elaine; Palacios, Tomás

2018-01-01

This work develops the first frequency-dependent small-signal model for graphene electrolyte-gated field-effect transistors (EGFETs). Graphene EGFETs are microfabricated to measure intrinsic voltage gain, frequency response, and to develop a frequency-dependent small-signal model. The transfer function of the graphene EGFET small-signal model is found to contain a unique pole due to a resistive element, which stems from electrolyte gating. Intrinsic voltage gain, cutoff frequency, and transition frequency for the microfabricated graphene EGFETs are approximately 3.1 V/V, 1.9 kHz, and 6.9 kHz, respectively. This work marks a critical step in the development of high-speed chemical and biological sensors using graphene EGFETs. PMID:29414868

HIRDLS Observations and Simulation of a Lower Stratospheric Intrusion of Tropical Air to High Latitudes

NASA Technical Reports Server (NTRS)

Olsen, Mark A.; Douglass, Anne R.; Newman, Paul A.; Gille, John C.; Nardi, Bruno; Yudin, Valery A.; Kinnison, Douglas E.; Khosravi, Rashid

2008-01-01

On 26 January 2006, the High Resolution Dynamic Limb Sounder (HIRDLS) observed low mixing ratios of ozone and nitric acid in an approximately 2 km vertical layer near 100 hPa extending from the subtropics to 55 degrees N over North America. The subsequent evolution of the layer is simulated with the Global Modeling Initiative (GMI) model and substantiated with HIRDLS observations. Air with low mixing ratios of ozone is transported poleward to 80 degrees N. Although there is evidence of mixing with extratropical air and diabatic descent, much of the tropical intrusion returns to the subtropics. This study demonstrates that HIRDLS and the GMI model are capable of resolving thin intrusion events. The observations combined with simulation are a first step towards development of a quantitative understanding of the lower stratospheric ozone budget.

The effectiveness of anticellulite treatment using tripolar radiofrequency monitored by classic and high-frequency ultrasound.

PubMed

Mlosek, R K; Woźniak, W; Malinowska, S; Lewandowski, M; Nowicki, A

2012-06-01

  Cellulite affects nearly 85% of the female population. Given the size of the phenomenon, we are continuously looking for effective ways to reduce cellulite. Reliable monitoring of anticellulite treatment remains a problem.   The main aim of the study was to evaluate the effectiveness of anticellulite treatment carried out using radiofrequency (RF), which was monitored by classical and high-frequency ultrasound.   Twenty-eight women underwent anticellulite treatment using RF, 17 women were in the placebo group. The therapy was monitored by classical and high-frequency ultrasound. The examinations evaluated the thickness of the epidermal echo, dermis thickness, dermis echogenicity, the length of the subcutaneous tissue bands growing into the dermis, the presence or absence of oedema, the thickness of subcutaneous tissue as well as thigh circumference and the stage of cellulite (according to the Nürnberger-Müller scale).   Cellulite was reduced in 89.286% of the women who underwent RF treatment. After the therapy, the following observations were made: a decrease in the thickness of the dermis and subcutaneous tissue, an increase in echogenicity reflecting on the increase in the number of collagen fibres, decreased subcutaneous tissue growing into bands in the dermis, and the reduction of oedema. In the placebo group, no statistically significant changes of the above parameters were observed.   Radiofrequency enables cellulite reduction. A crucial aspect is proper monitoring of the progress of such therapy, which ultrasound allows. © 2011 The Authors. Journal of the European Academy of Dermatology and Venereology © 2011 European Academy of Dermatology and Venereology.

Inter-comparison of Precipitation Estimation Derived from GPM Dual-frequency Radar and CSU-CHILL Radar

NASA Astrophysics Data System (ADS)

Chen, S.; Chen, H.; Hu, J.; Zhang, A.; Min, C.

2017-12-01

It is more than 3 years since the launch of Global Precipitation Measurement (GPM) core satellite on February 27 2014. This satellite carries two core sensors, i.e. dual-frequency precipitation radar (DPR) and microwave imager (GMI). These two sensors are of the state-of- the-art sensors that observe the precipitation over the globe. The DPR level-2 product provides both precipitation rates and phases. The precipitation phase information can help advance global hydrological cycle modeling, particularly crucial for high-altitude and high latitude regions where solid precipitation is the dominated source of water. However, people are still in short of the reliability and accuracy of DPR level-2 product. Assess the performance and uncertainty of precipitation retrievals derived from the core sensor dual-frequency precipitation radar (DPR) on board the satellite is needed for the precipitation algorithm developers and the end users in hydrology, weather, meteorology, and hydro-related communities. In this study, the precipitation estimation derived from DPR is compared with that derived from CSU-CHILL National Weather Radar from March 2014 to October 2017. The CSU-CHILL radar is located in Greeley, CO, and is an advanced, transportable dual-polarized dual-wavelength (S- and X-band) weather radar. The system and random errors of DPR in measuring precipitation will be analyzed as a function of the precipitation rate and precipitation type (liquid and solid). This study is expected to offer insights into performance of the most advanced sensor and thus provide useful feedback to the algorithm developers as well as the GPM data end users.

Effective deep brain stimulation suppresses low-frequency network oscillations in the basal ganglia by regularizing neural firing patterns.

PubMed

McConnell, George C; So, Rosa Q; Hilliard, Justin D; Lopomo, Paola; Grill, Warren M

2012-11-07

Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective treatment for the motor symptoms of Parkinson's disease (PD). The effects of DBS depend strongly on stimulation frequency: high frequencies (>90 Hz) improve motor symptoms, while low frequencies (<50 Hz) are either ineffective or exacerbate symptoms. The neuronal basis for these frequency-dependent effects of DBS is unclear. The effects of different frequencies of STN-DBS on behavior and single-unit neuronal activity in the basal ganglia were studied in the unilateral 6-hydroxydopamine lesioned rat model of PD. Only high-frequency DBS reversed motor symptoms, and the effectiveness of DBS depended strongly on stimulation frequency in a manner reminiscent of its clinical effects in persons with PD. Quantification of single-unit activity in the globus pallidus externa (GPe) and substantia nigra reticulata (SNr) revealed that high-frequency DBS, but not low-frequency DBS, reduced pathological low-frequency oscillations (∼9 Hz) and entrained neurons to fire at the stimulation frequency. Similarly, the coherence between simultaneously recorded pairs of neurons within and across GPe and SNr shifted from the pathological low-frequency band to the stimulation frequency during high-frequency DBS, but not during low-frequency DBS. The changes in firing patterns in basal ganglia neurons were not correlated with changes in firing rate. These results indicate that high-frequency DBS is more effective than low-frequency DBS, not as a result of changes in firing rate, but rather due to its ability to replace pathological low-frequency network oscillations with a regularized pattern of neuronal firing.

Effective deep brain stimulation suppresses low frequency network oscillations in the basal ganglia by regularizing neural firing patterns

PubMed Central

McConnell, George C.; So, Rosa Q.; Hilliard, Justin D; Lopomo, Paola; Grill, Warren M.

2012-01-01

Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective treatment for the motor symptoms of Parkinson’s disease (PD). The effects of DBS depend strongly on stimulation frequency: high frequencies (>90Hz) improve motor symptoms, while low frequencies (<50Hz) are either ineffective or exacerbate symptoms. The neuronal basis for these frequency-dependent effects of DBS is unclear. The effects of different frequencies of STN-DBS on behavior and single-unit neuronal activity in the basal ganglia were studied in the unilateral 6-hydroxydopamine lesioned rat model of PD. Only high frequency DBS reversed motor symptoms and the effectiveness of DBS depended strongly on stimulation frequency in a manner reminiscent of its clinical effects in persons with PD. Quantification of single-unit activity in the globus pallidus externa (GPe) and substantia nigra reticulata (SNr) revealed that high frequency DBS, but not low frequency DBS, reduced pathological low frequency oscillations (~9Hz) and entrained neurons to fire at the stimulation frequency. Similarly, the coherence between simultaneously recorded pairs of neurons within and across GPe and SNr shifted from the pathological low frequency band to the stimulation frequency during high frequency DBS, but not during low frequency DBS. The changes in firing patterns in basal ganglia neurons were not correlated with changes in firing rate. These results indicate that high frequency DBS is more effective than low frequency DBS, not as a result of changes in firing rate, but rather due to its ability to replace pathological low frequency network oscillations with a regularized pattern of neuronal firing. PMID:23136407

Frequency selection rule for high definition and high frame rate Lissajous scanning.

PubMed

Hwang, Kyungmin; Seo, Yeong-Hyeon; Ahn, Jinhyo; Kim, Pilhan; Jeong, Ki-Hun

2017-10-26

Lissajous microscanners are very attractive in compact laser scanning applications such as endomicroscopy or pro-projection display owing to high mechanical stability and low operating voltages. The scanning frequency serves as a critical factor for determining the scanning imaging quality. Here we report the selection rule of scanning frequencies that can realize high definition and high frame-rate (HDHF) full-repeated Lissajous scanning imaging. The fill factor (FF) monotonically increases with the total lobe number of a Lissajous curve, i.e., the sum of scanning frequencies divided by the great common divisor (GCD) of bi-axial scanning frequencies. The frames per second (FPS), called the pattern repeated rate or the frame rate, linearly increases with GCD. HDHF Lissajous scanning is achieved at the bi-axial scanning frequencies, where the GCD has the maximum value among various sets of the scanning frequencies satisfying the total lobe number for a target FF. Based on this selection rule, the experimental results clearly demonstrate that conventional Lissajous scanners substantially increase both FF and FPS by slightly modulating the scanning frequencies at near the resonance within the resonance bandwidth of a Lissajous scanner. This selection rule provides a new guideline for HDHF Lissajous scanning in compact laser scanning systems.

Border effect-based precise measurement of any frequency signal

NASA Astrophysics Data System (ADS)

Bai, Li-Na; Ye, Bo; Xuan, Mei-Na; Jin, Yu-Zhen; Zhou, Wei

2015-12-01

Limited detection resolution leads to fuzzy areas during the measurement, and the discrimination of the border of a fuzzy area helps to use the resolution stability. In this way, measurement precision is greatly improved, hence this phenomenon is named the border effect. The resolution fuzzy area and its application should be studied to realize high-resolution measurement. During the measurement of any frequency signal, the fuzzy areas of phase-coincidence detection are always discrete and irregular. In this paper the difficulty in capturing the border information of discrete fuzzy areas is overcome and extra-high resolution measurement is implemented. Measurement precision of any frequency-signal can easily reach better than 1 × 10-11/s in a wide range of frequencies, showing the great importance of the border effect. An in-depth study of this issue has great significance for frequency standard comparison, signal processing, telecommunication, and fundamental subjects. Project supported by the National Natural Science Foundation of China (Grant Nos. 10978017 and 61201288), the Natural Science Foundation of Research Plan Projects of Shaanxi Province, China (Grant No. 2014JM2-6128), and the Sino-Poland Science and Technology Cooperation Projects (Grant No. 36-33).

High-frequency large-amplitude oscillations of a non-isothermal N/S boundary

NASA Astrophysics Data System (ADS)

Bezuglyj, A. I.; Shklovskij, V. A.

2016-10-01

Within the framework of a phenomenological approach based on the heat balance equation and the current dependence of the critical temperature of the superconductor, the effect of high-frequency current of large amplitude and arbitrary waveform on the non-isothermal balance of an oscillating N/S interface in a long superconductor was studied. Self-consistent average temperature field of the rapidly oscillating non-isothermal N/S boundary (heat kink) was introduced, which allowed us to go beyond the well-known concept of mean-square heating and consider the effect of the current waveform. With regard to experiments on the effects of high-power microwave radiation on the current-voltage (IV) characteristics of superconducting films, their classification was performed and the families of IV curves of inhomogeneous superconductors carrying a current containing a high-frequency component of large amplitude. Several IV curves exhibited a hysteresis of thermal nature.

Noise measurements during high-frequency oscillatory and conventional mechanical ventilation.

PubMed

Berens, R J; Weigle, C G

1995-10-01

To evaluate the noise levels with high-frequency oscillatory ventilation and conventional mechanical ventilation. An observational, prospective study. Pediatric intensive care unit. The caretakers and environment of the pediatric intensive care unit. High-frequency oscillatory and conventional mechanical ventilation. Caretakers evaluated noise using a visual analog scale. Noise was measured with a decibel meter and an octave band frequency filter. There was twice as much noise perceived by the caretakers and as measured on the decibel A scale. All measures showed significantly greater noise, especially at low frequencies, with high-frequency oscillatory ventilation. High-frequency oscillatory ventilation exposes the patient to twice as much noise as does the use of conventional mechanical ventilation.

High frequency source localization in a shallow ocean sound channel using frequency difference matched field processing.

PubMed

Worthmann, Brian M; Song, H C; Dowling, David R

2015-12-01

Matched field processing (MFP) is an established technique for source localization in known multipath acoustic environments. Unfortunately, in many situations, particularly those involving high frequency signals, imperfect knowledge of the actual propagation environment prevents accurate propagation modeling and source localization via MFP fails. For beamforming applications, this actual-to-model mismatch problem was mitigated through a frequency downshift, made possible by a nonlinear array-signal-processing technique called frequency difference beamforming [Abadi, Song, and Dowling (2012). J. Acoust. Soc. Am. 132, 3018-3029]. Here, this technique is extended to conventional (Bartlett) MFP using simulations and measurements from the 2011 Kauai Acoustic Communications MURI experiment (KAM11) to produce ambiguity surfaces at frequencies well below the signal bandwidth where the detrimental effects of mismatch are reduced. Both the simulation and experimental results suggest that frequency difference MFP can be more robust against environmental mismatch than conventional MFP. In particular, signals of frequency 11.2 kHz-32.8 kHz were broadcast 3 km through a 106-m-deep shallow ocean sound channel to a sparse 16-element vertical receiving array. Frequency difference MFP unambiguously localized the source in several experimental data sets with average peak-to-side-lobe ratio of 0.9 dB, average absolute-value range error of 170 m, and average absolute-value depth error of 10 m.

High-frequency electroacupuncture evidently reinforces hippocampal synaptic transmission in Alzheimer's disease rats

PubMed Central

Li, Wei; Kong, Li-hong; Wang, Hui; Shen, Feng; Wang, Ya-wen; Zhou, Hua; Sun, Guo-jie

2016-01-01

The frequency range of electroacupuncture in treatment of Alzheimer's disease in rats is commonly 2–5 Hz (low frequency) and 50–100 Hz (high frequency). We established a rat model of Alzheimer's disease by injecting β-amyloid 1–42 (Aβ1–42) into the bilateral hippocampal dentate gyrus to verify which frequency may be better suited in treatment. Electroacupuncture at 2 Hz or 50 Hz was used to stimulate Baihui (DU20) and Shenshu (BL23) acupoints. The water maze test and electrophysiological studies demonstrated that spatial memory ability was apparently improved, and the ranges of long-term potentiation and long-term depression were increased in Alzheimer's disease rats after electroacupuncture treatment. Moreover, the effects of electroacupuncture at 50 Hz were better than that at 2 Hz. These findings suggest that high-frequency electroacupuncture may enhance hippocampal synaptic transmission and potentially improve memory disorders in Alzheimer's disease rats. PMID:27335565

Effects of aging and text-stimulus quality on the word-frequency effect during Chinese reading.

PubMed

Wang, Jingxin; Li, Lin; Li, Sha; Xie, Fang; Liversedge, Simon P; Paterson, Kevin B

2018-06-01

Age-related reading difficulty is well established for alphabetic languages. Compared to young adults (18-30 years), older adults (65+ years) read more slowly, make more and longer fixations, make more regressions, and produce larger word-frequency effects. However, whether similar effects are observed for nonalphabetic languages like Chinese remains to be determined. In particular, recent research has suggested Chinese readers experience age-related reading difficulty but do not produce age differences in the word-frequency effect. This might represent an important qualitative difference in aging effects, so we investigated this further by presenting young and older adult Chinese readers with sentences that included high- or low-frequency target words. Additionally, to test theories that suggest reductions in text-stimulus quality differentially affect lexical processing by adult age groups, we presented either the target words (Experiment 1) or all characters in sentences (Experiment 2) normally or with stimulus quality reduced. Analyses based on mean eye-movement parameters and distributional analyses of fixation times for target words showed typical age-related reading difficulty. We also observed age differences in the word-frequency effect, predominantly in the tails of fixation-time distributions, consistent with an aging effect on the processing of high- and low-frequency words. Reducing stimulus quality disrupted eye movements more for the older readers, but the influence of stimulus quality on the word-frequency effect did not differ across age groups. This suggests Chinese older readers' lexical processing is resilient to reductions in stimulus quality, perhaps due to greater experience recognizing words from impoverished visual input. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Modulatory effects of high-frequency repetitive transcranial magnetic stimulation on the ipsilateral silent period.

PubMed

Cincotta, M; Giovannelli, F; Borgheresi, A; Balestrieri, F; Zaccara, G; Inghilleri, M; Berardelli, A

2006-06-01

In healthy subjects, suprathreshold repetitive transcranial magnetic stimulation (rTMS) at frequencies >2 Hz prolongs the cortical silent period (CSP) over the course of the train. This progressive lengthening probably reflects temporal summation of the inhibitory interneurons in the stimulated primary motor cortex (M1). In this study, we tested whether high-frequency rTMS also modulates the ipsilateral silent period (ISP). In nine normal subjects, suprathreshold 10-pulse rTMS trains were delivered to the right M1 at frequencies of 3, 5, and 10 Hz during maximal isometric contraction of both first dorsal interosseous muscles. At 10 Hz, the second pulse of the train increased the area of the ISP; the other stimuli did not increase it further. During rTMS at 3 and 5 Hz, the ISP remained significantly unchanged. Control experiments showed that 10-Hz rTMS delivered at subthreshold intensity also increased the ISP. rTMS over the hand motor area did not facilitate ISPs in the biceps muscles. Finally, rTMS-induced ISP facilitation did not outlast the 10-Hz rTMS train. These findings suggest that rTMS at a frequency of 10 Hz potentiates the interhemispheric inhibitory mechanisms responsible for the ISP, partly through temporal summation. The distinct changes in the ISP and CSP suggest that rTMS facilitates intrahemispheric and interhemispheric inhibitory phenomena through separate neural mechanisms. The ISP facilitation induced by high-frequency rTMS is a novel, promising tool to investigate pathophysiological abnormal interhemispheric inhibitory transfer in various neurological diseases.

High frequency, high temperature specific core loss and dynamic B-H hysteresis loop characteristics of soft magnetic alloys

NASA Technical Reports Server (NTRS)

Wieserman, W. R.; Schwarze, G. E.; Niedra, J. M.

1990-01-01

Limited experimental data exists for the specific core loss and dynamic B-H loops for soft magnetic materials for the combined conditions of high frequency and high temperature. This experimental study investigates the specific core loss and dynamic B-H loop characteristics of Supermalloy and Metglas 2605SC over the frequency range of 1 to 50 kHz and temperature range of 23 to 300 C under sinusoidal voltage excitation. The experimental setup used to conduct the investigation is described. The effects of the maximum magnetic flux density, frequency, and temperature on the specific core loss and on the size and shape of the B-H loops are examined.

Center for High-Frequency Microelectronics

DTIC Science & Technology

1992-08-31

34 IEEE Transactions on Electron Devices, 38, No. 6, pp. 1324-1333, June 1991. 185. C. C. Chen, R. K. Mains and G. I. Haddad, " High - Power Generation in...Weiss, J. Hu and W.-P. Hong, "Electronic 0 Properties of Power High Electron Mobility Transistors," Conference on Ballistic Electrons for Transistors...method at higher frequencies than previously believed. - Calculations of high - power generation modes in Si IMPATT devices in the 100-200 GHz range have

High-frequency combination coding-based steady-state visual evoked potential for brain computer interface

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Feng; Zhang, Xin; Xie, Jun

2015-03-10

This study presents a new steady-state visual evoked potential (SSVEP) paradigm for brain computer interface (BCI) systems. The goal of this study is to increase the number of targets using fewer stimulation high frequencies, with diminishing subject’s fatigue and reducing the risk of photosensitive epileptic seizures. The new paradigm is High-Frequency Combination Coding-Based High-Frequency Steady-State Visual Evoked Potential (HFCC-SSVEP).Firstly, we studied SSVEP high frequency(beyond 25 Hz)response of SSVEP, whose paradigm is presented on the LED. The SNR (Signal to Noise Ratio) of high frequency(beyond 40 Hz) response is very low, which is been unable to be distinguished through the traditional analysis method;more » Secondly we investigated the HFCC-SSVEP response (beyond 25 Hz) for 3 frequencies (25Hz, 33.33Hz, and 40Hz), HFCC-SSVEP produces n{sup n} with n high stimulation frequencies through Frequence Combination Code. Further, Animproved Hilbert-huang transform (IHHT)-based variable frequency EEG feature extraction method and a local spectrum extreme target identification algorithmare adopted to extract time-frequency feature of the proposed HFCC-SSVEP response.Linear predictions and fixed sifting (iterating) 10 time is used to overcome the shortage of end effect and stopping criterion,generalized zero-crossing (GZC) is used to compute the instantaneous frequency of the proposed SSVEP respondent signals, the improved HHT-based feature extraction method for the proposed SSVEP paradigm in this study increases recognition efficiency, so as to improve ITR and to increase the stability of the BCI system. what is more, SSVEPs evoked by high-frequency stimuli (beyond 25Hz) minimally diminish subject’s fatigue and prevent safety hazards linked to photo-induced epileptic seizures, So as to ensure the system efficiency and undamaging.This study tests three subjects in order to verify the feasibility of the proposed method.« less

Power Supply for Variable Frequency Induction Heating Using MERS Soft-Switching High Frequency Inverter

NASA Astrophysics Data System (ADS)

Isobe, Takanori; Kitahara, Tadayuki; Fukutani, Kazuhiko; Shimada, Ryuichi

Variable frequency induction heating has great potential for industrial heating applications due to the possibility of achieving heating distribution control; however, large-scale induction heating with variable frequency has not yet been introduced for practical use. This paper proposes a high frequency soft-switching inverter for induction heating that can achieve variable frequency operation. One challenge of variable frequency induction heating is increasing power electronics ratings. This paper indicates that its current source type dc-link configuration and soft-switching characteristics can make it possible to build a large-scale system with variable frequency capability. A 90-kVA 150-1000Hz variable frequency experimental power supply for steel strip induction heating was developed. Experiments confirmed the feasibility of variable frequency induction heating with proposed converter and the advantages of variable frequency operation.

HIGH-DOSE HIGH-FREQUENCY AFLIBERCEPT FOR RECALCITRANT NEOVASCULAR AGE-RELATED MACULAR DEGENERATION.

PubMed

You, Qi Sheng; Gaber, Raouf; Meshi, Amit; Ramkumar, Hema L; Alam, Mostafa; Muftuoglu, Ilkay Kilic; Freeman, William R

2018-06-01

To determine the efficacy of monthly (0.1 mL/4 mg) aflibercept for refractory neovascular age-related macular degeneration (wet age-related macular degeneration). This was a retrospective interventional case series in which patients with wet age-related macular degeneration were treated with stepwise dose escalation. Nonvitrectomized patients resistant to monthly (Q4W) ranibizumab/bevacizumab were switched to 2 mg aflibercept every 8 weeks. With resistance, they were escalated to Q4W 2 mg aflibercept, then Q4W 4 mg (high dose high frequency, 4Q4W) aflibercept. Resistance was defined as ≥2 recurrences after being dry following ≥3 injections or persistent exudation on treatment of ≥5 injections. Thirty-three eyes of 28 patients were treated with 4Q4W aflibercept and followed for a mean of 16 months. A dry retina (no intraretinal or subretinal fluid) was achieved after initiating 4Q4W aflibercept treatment at a mean of 3.8 months. Central foveal thickness, maximum foveal thickness, intraretinal fluid, subretinal fluid, and retinal pigment detachment height decreased significantly at 1 month after initiating the 4Q4W aflibercept, and the morphologic therapeutic effect was sustained until the last visit. Forty-five percent of eyes had one or more lines of vision improvement. New geographic atrophy developed in 9% of eyes during follow-up. No ocular or systemic adverse events occurred after initiating 4Q4W aflibercept. Intravitreal high-dose high-frequency aflibercept is an effective treatment for patients with refractory wet age-related macular degeneration.

[Pulse-modulated Electromagnetic Radiation of Extremely High Frequencies Protects Cellular DNA against Damaging Effect of Physico-Chemical Factors in vitro].

PubMed

Gapeyev, A B; Lukyanova, N A

2015-01-01

Using a comet assay technique, we investigated protective effects of. extremely high frequency electromagnetic radiation in combination with the damaging effect of X-ray irradiation, the effect of damaging agents hydrogen peroxide and methyl methanesulfonate on DNA in mouse whole blood leukocytes. It was shown that the preliminary exposure of the cells to low intensity pulse-modulated electromagnetic radiation (42.2 GHz, 0.1 mW/cm2, 20-min exposure, modulation frequencies of 1 and 16 Hz) caused protective effects decreasing the DNA damage by 20-45%. The efficacy of pulse-modulated electromagnetic radiation depended on the type of genotoxic agent and increased in a row methyl methanesulfonate--X-rays--hydrogen peroxide. Continuous electromagnetic radiation was ineffective. The mechanisms of protective effects may be connected with an induction of the adaptive response by nanomolar concentrations of reactive oxygen species formed by pulse-modulated electromagnetic radiation.

Neurofeedback of SMR and Beta1 Frequencies: An Investigation of Learning Indices and Frequency-Specific Effects.

PubMed

Pimenta, Miguel G; van Run, Chris; de Fockert, Jan W; Gruzelier, John H

2018-05-15

Despite evidence that Sensorimotor Rhythm (SMR) and beta1 neurofeedback have distinct cognitive enhancement effects, it remains unclear whether their amplitudes can be independently enhanced. Furthermore, demands for top-down attention control, postural restraint and maintenance of cognitive set processes, all requiring low-beta frequencies, might masquerade as learning and confound interpretation. The feasibility of selectively enhancing SMR and beta1 amplitudes was investigated with the addition of a random frequency control condition that also requires the potentially confounding cognitive processes. A comprehensive approach to assessing neurofeedback learning was undertaken through the calculation of learning indices within- and across-session and pre-to-post baseline. Herein we provide the first demonstration of beta1 within-session amplitude learning that was not attributable to extraneous cognitive processes, for it was not found with random frequency training. On the other hand, within-session SMR learning might have been obscured by high interindividual variability and methodological limitations such as the type of feedback screen, the insufficient number of sessions, and the exclusion of simultaneous theta and high-beta inhibition. Interestingly, SMR and beta1 amplitude increased across sessions in the three groups suggesting unspecific effects of neurofeedback in the low beta frequency band. Moreover, there was no clear evidence of frequency specificity associated with either SMR or beta1 training. Some methodological limitations may underpin the divergent results with previous studies. Copyright © 2017 IBRO. All rights reserved.

The Exponent of High-frequency Source Spectral Falloff and Contribution to Source Parameter Estimates

NASA Astrophysics Data System (ADS)

Kiuchi, R.; Mori, J. J.

2015-12-01

As a way to understand the characteristics of the earthquake source, studies of source parameters (such as radiated energy and stress drop) and their scaling are important. In order to estimate source parameters reliably, often we must use appropriate source spectrum models and the omega-square model is most frequently used. In this model, the spectrum is flat in lower frequencies and the falloff is proportional to the angular frequency squared. However, Some studies (e.g. Allmann and Shearer, 2009; Yagi et al., 2012) reported that the exponent of the high frequency falloff is other than -2. Therefore, in this study we estimate the source parameters using a spectral model for which the falloff exponent is not fixed. We analyze the mainshock and larger aftershocks of the 2008 Iwate-Miyagi Nairiku earthquake. Firstly, we calculate the P wave and SH wave spectra using empirical Green functions (EGF) to remove the path effect (such as attenuation) and site effect. For the EGF event, we select a smaller earthquake that is highly-correlated with the target event. In order to obtain the stable results, we calculate the spectral ratios using a multitaper spectrum analysis (Prieto et al., 2009). Then we take a geometric mean from multiple stations. Finally, using the obtained spectra ratios, we perform a grid search to determine the high frequency falloffs, as well as corner frequency of both of events. Our results indicate the high frequency falloff exponent is often less than 2.0. We do not observe any regional, focal mechanism, or depth dependencies for the falloff exponent. In addition, our estimated corner frequencies and falloff exponents are consistent between the P wave and SH wave analysis. In our presentation, we show differences in estimated source parameters using a fixed omega-square model and a model allowing variable high-frequency falloff.

Metronidazole as a protector of cells from electromagnetic radiation of extremely high frequencies

NASA Astrophysics Data System (ADS)

Kuznetsov, Pavel E.; Malinina, Ulia A.; Popyhova, Era B.; Rogacheva, Svetlana M.; Somov, Alexander U.

2006-08-01

It is well known that weak electromagnetic fields of extremely high frequencies cause significant modification of the functional status of biological objects of different levels of organization. The aim of the work was to study the combinatory effect of metronidazole - the drug form of 1-(2'hydroxiethil)-2-methil-5-nitroimidazole - and electromagnetic radiation of extremely high frequencies (52...75 GHz) on the hemolytic stability of erythrocytes and hemotaxis activity of Infusoria Paramecium caudatum.

GPM Microwave Imager Engineering Model Results

NASA Technical Reports Server (NTRS)

Newell, David; Krimchansky, Sergey

2010-01-01

The Global Precipitation Measurement (GPM) Microwave Imager (GMI) Instrument is being developed by Ball Aerospace and Technology Corporation (BATC) for the GPM program at NASA Goddard. The Global Precipitation Measurement (GPM) mission is an international effort managed by the National Aeronautics and Space Administration (NASA) to improve climate, weather, and hydro-meteorological predictions through more accurate and more frequent precipitation measurements. The GPM Microwave Imager (GMI) will be used to make calibrated, radiometric measurements from space at multiple microwave frequencies and polarizations. GMI will be placed on the GPM Core Spacecraft together with the Dualfrequency Precipitation Radar (DPR). The DPR is two-frequency precipitation measurement radar, which will operate in the Ku-band and Ka-band of the microwave spectrum. The Core Spacecraft will make radiometric and radar measurements of clouds and precipitation and will be the central element ofGPM's space segment. The data products from GPM will provide information concerning global precipitation on a frequent, near-global basis to meteorologists and scientists making weather forecasts and performing research on the global energy and water cycle, precipitation, hydrology, and related disciplines. In addition, radiometric measurements from GMI and radar measurements from the DPR will be used together to develop a retrieval transfer standard for the purpose of calibrating precipitation retrieval algorithms. This calibration standard will establish a reference against which other retrieval algorithms using only microwave radiometers (and without the benefit of the DPR) on other satellites in the GPM constellation will be compared.

Cross-education after high-frequency versus low-frequency volume-matched handgrip training.

PubMed

Boyes, Natasha G; Yee, Peter; Lanovaz, Joel L; Farthing, Jonathan P

2017-10-01

Cross-education training programs cause interlimb asymmetry of strength and hypertrophy. We examined the cross-education effects from a high-frequency (HF) versus a low-frequency (LF) volume-matched handgrip training program on interlimb asymmetry. Right-handed participants completed either HF (n = 10; 2 × 6 repetitions 10 times per week) or LF (n = 9; 5 × 8 repetitions 3 times per week) training. Testing occurred twice before and once after 4 weeks of right-handed isometric handgrip training totaling 120 weekly repetitions. Measures were maximal isometric handgrip and wrist flexion torque, muscle thickness, and muscle activation (electromyography; EMG). Grip strength was greater in both limbs posttraining, pooled across groups (P < 0.001). Trained limb muscle thickness increased in both groups (P < 0.05; untrained, P = 0.897). EMG and wrist flexion torque did not change (all P > 0.103). Both LF and HF induced cross-education of grip strength to the untrained limb, but HF did not reduce asymmetry. These findings have implications for injury rehabilitation. Muscle Nerve 56: 689-695, 2017. © 2017 Wiley Periodicals, Inc.

Effects of spatial frequency content on classification of face gender and expression.

PubMed

Aguado, Luis; Serrano-Pedraza, Ignacio; Rodríguez, Sonia; Román, Francisco J

2010-11-01

The role of different spatial frequency bands on face gender and expression categorization was studied in three experiments. Accuracy and reaction time were measured for unfiltered, low-pass (cut-off frequency of 1 cycle/deg) and high-pass (cutoff frequency of 3 cycles/deg) filtered faces. Filtered and unfiltered faces were equated in root-mean-squared contrast. For low-pass filtered faces reaction times were higher than unfiltered and high-pass filtered faces in both categorization tasks. In the expression task, these results were obtained with expressive faces presented in isolation (Experiment 1) and also with neutral-expressive dynamic sequences where each expressive face was preceded by a briefly presented neutral version of the same face (Experiment 2). For high-pass filtered faces different effects were observed on gender and expression categorization. While both speed and accuracy of gender categorization were reduced comparing to unfiltered faces, the efficiency of expression classification remained similar. Finally, we found no differences between expressive and non expressive faces in the effects of spatial frequency filtering on gender categorization (Experiment 3). These results show a common role of information from the high spatial frequency band in the categorization of face gender and expression.

A role for high frequency hydrochemical sampling in long term ecosystem studies

NASA Astrophysics Data System (ADS)

Sebestyen, S. D.; Shanley, J. B.; Boyer, E. W.; Kendall, C.

2007-12-01

Monitoring of surface waters for major chemical constituents is needed to assess long-term trends and responses to ecological disturbance. However, the typical fixed-interval (weekly, monthly, or quarterly) sampling schemes of most long-term ecosystem studies may not capture the full range of stream chemical variation and do not always provide enough information to discern the landscape processes that control surface water chemistry and solute loadings. To expand upon traditional hydrochemical monitoring, we collected high frequency event-based surface water samples at an upland, forested basin of the Sleepers River Research Watershed (Vermont, USA), one of five intensively studied sites in the Water, Energy, and Biogeochemical Budgets (WEBB) program of the US Geological Survey. We present several examples that highlight the importance of linking long-term weekly data with intensive, high frequency sampling. We used end-member mixing analysis and isotopic approaches to trace sources of stream nutrients (e.g. nitrate, dissolved organic carbon) and quantified how atmospheric pollutants (e.g. nitrogen, sulfate, and mercury) affect stream chemistry. High frequency sampling generates large numbers of samples and is both labor and resource intensive but yields insights into ecosystem functions that are not readily discerned from less-frequent sampling. As the ecological community contemplates the scope and foci of environmental observatories as benchmarks for deciphering the effects of natural and anthropogenic change, incorporating high frequency hydrochemical sampling will further our understanding of ecosystem functions across a range of ecosystem types and disturbance effects.

Late administration of high-frequency electrical stimulation increases nerve regeneration without aggravating neuropathic pain in a nerve crush injury.

PubMed

Su, Hong-Lin; Chiang, Chien-Yi; Lu, Zong-Han; Cheng, Fu-Chou; Chen, Chun-Jung; Sheu, Meei-Ling; Sheehan, Jason; Pan, Hung-Chuan

2018-06-25

High-frequency transcutaneous neuromuscular electrical nerve stimulation (TENS) is currently used for the administration of electrical current in denervated muscle to alleviate muscle atrophy and enhance motor function; however, the time window (i.e. either immediate or delayed) for achieving benefit is still undetermined. In this study, we conducted an intervention of sciatic nerve crush injury using high-frequency TENS at different time points to assess the effect of motor and sensory functional recovery. Animals with left sciatic nerve crush injury received TENS treatment starting immediately after injury or 1 week later at a high frequency(100 Hz) or at a low frequency (2 Hz) as a control. In SFI gait analysis, either immediate or late admission of high-frequency electrical stimulation exerted significant improvement compared to either immediate or late administration of low-frequency electrical stimulation. In an assessment of allodynia, immediate high frequency electrical stimulation caused a significantly decreased pain threshold compared to late high-frequency or low-frequency stimulation at immediate or late time points. Immunohistochemistry staining and western blot analysis of S-100 and NF-200 demonstrated that both immediate and late high frequency electrical stimulation showed a similar effect; however the effect was superior to that achieved with low frequency stimulation. Immediate high frequency electrical stimulation resulted in significant expression of TNF-α and synaptophysin in the dorsal root ganglion, somatosensory cortex, and hippocampus compared to late electrical stimulation, and this trend paralleled the observed effect on somatosensory evoked potential. The CatWalk gait analysis also showed that immediate electrical stimulation led to a significantly high regularity index. In primary dorsal root ganglion cells culture, high-frequency electrical stimulation also exerted a significant increase in expression of TNF-α, synaptophysin, and

Magnetoelectric effect in nanogranular FeCo-MgF films at GHz frequencies

NASA Astrophysics Data System (ADS)

Ikeda, Kenji; Kobayashi, Nobukiyo; Arai, Ken-Ichi; Yabukami, Shin

2018-01-01

The magnetoelectric effect is a key issue for material science and is particularly significant in the high frequency band, where it is indispensable in industrial applications. Here, we present for the first time, a study of the high frequency tunneling magneto-dielectric (TMD) effect in nanogranular FeCo-MgF films, consisting of nanometer-sized magnetic FeCo granules dispersed in an MgF insulator matrix. Dielectric relaxation and the TMD effect are confirmed at frequencies over 10 MHz. The frequency dependence of dielectric relaxation is described by the Debye-Fröhlich model, taking relaxation time dispersion into account, which reflects variations in the nature of the microstructure, such as granule size, and the inter-spacing between the granules that affect the dielectric response. The TMD effect reaches a maximum at a frequency that is equivalent to the inverse of the relaxation time. The frequency where the peak TMD effect is observed varies between 12 MHz and 220 MHz, depending on the concentration of magnetic metal in the nanogranular films. The inter-spacing of the films decreases with increasing magnetic metal concentration, in accordance with the relaxation time. These results indicate that dielectric relaxation is controlled by changing the nanostructure, using the deposition conditions. A prospective application of these nanogranular films is in tunable impedance devices for next-generation mobile communication systems, at frequencies over 1 GHz, where capacitance is controlled using the applied magnetic field.

High Frequency Plasma Generators for Ion Thrusters

NASA Technical Reports Server (NTRS)

Divergilio, W. F.; Goede, H.; Fosnight, V. V.

1981-01-01

The results of a one year program to experimentally adapt two new types of high frequency plasma generators to Argon ion thrusters and to analytically study a third high frequency source concept are presented. Conventional 30 cm two grid ion extraction was utilized or proposed for all three sources. The two plasma generating methods selected for experimental study were a radio frequency induction (RFI) source, operating at about 1 MHz, and an electron cyclotron heated (ECH) plasma source operating at about 5 GHz. Both sources utilize multi-linecusp permanent magnet configurations for plasma confinement. The plasma characteristics, plasma loading of the rf antenna, and the rf frequency dependence of source efficiency and antenna circuit efficiency are described for the RFI Multi-cusp source. In a series of tests of this source at Lewis Research Center, minimum discharge losses of 220+/-10 eV/ion were obtained with propellant utilization of .45 at a beam current of 3 amperes. Possible improvement modifications are discussed.

On-clip high frequency reliability and failure test structures

DOEpatents

Snyder, Eric S.; Campbell, David V.

1997-01-01

Self-stressing test structures for realistic high frequency reliability characterizations. An on-chip high frequency oscillator, controlled by DC signals from off-chip, provides a range of high frequency pulses to test structures. The test structures provide information with regard to a variety of reliability failure mechanisms, including hot-carriers, electromigration, and oxide breakdown. The system is normally integrated at the wafer level to predict the failure mechanisms of the production integrated circuits on the same wafer.

On-clip high frequency reliability and failure test structures

DOEpatents

Snyder, E.S.; Campbell, D.V.

1997-04-29

Self-stressing test structures for realistic high frequency reliability characterizations. An on-chip high frequency oscillator, controlled by DC signals from off-chip, provides a range of high frequency pulses to test structures. The test structures provide information with regard to a variety of reliability failure mechanisms, including hot-carriers, electromigration, and oxide breakdown. The system is normally integrated at the wafer level to predict the failure mechanisms of the production integrated circuits on the same wafer. 22 figs.

High Sensitive Scintillation Observations At Very Low Frequencies

NASA Astrophysics Data System (ADS)

Konovalenko, A. A.; Falkovich, I. S.; Kalinichenko, N. N.; Olyak, M. R.; Lecacheux, A.; Rosolen, C.; Bougeret, J.-L.; Rucker, H. O.; Tokarev, Yu.

The observation of interplanetary scintillations of compact radio sources is powerful method of solar wind diagnostics. This method is developed mainly at decimeter- meter wavelengths. New possibilities are opened at extremely low frequencies (decameter waves) especially at large elongations. Now this approach is being actively developed using high effective decameter antennas UTR-2, URAN and Nancay Decameter Array. New class of back-end facility like high dynamic range, high resolution digital spectral processors, as well as dynamic spectra determination ideology give us new opportunities for distinguishing of the ionospheric and interplanetary scintillations and for observations of large number of radio sources, whith different angular sizes and elongations, even for the cases of rather weak objects.

High-frequency high-voltage high-power DC-to-DC converters

NASA Astrophysics Data System (ADS)

Wilson, T. G.; Owen, H. A., Jr.; Wilson, P. M.

1981-07-01

The current and voltage waveshapes associated with the power transitor and the power diode in an example current-or-voltage step-up (buck-boost) converter were analyzed to highlight the problems and possible tradeoffs involved in the design of high voltage high power converters operating at switching frequencies in the range of 100 Khz. Although the fast switching speeds of currently available power diodes and transistors permit converter operation at high switching frequencies, the resulting time rates of changes of current coupled with parasitic inductances in series with the semiconductor switches, produce large repetitive voltage transients across the semiconductor switches, potentially far in excess of the device voltage ratings. The need is established for semiconductor switch protection circuitry to control the peak voltages appearing across the semiconductor switches, as well as to provide the waveshaping action require for a given semiconductor device. The possible tradeoffs, as well as the factors affecting the tradeoffs that must be considered in order to maximize the efficiency of the converters are enumerated.

High-frequency high-voltage high-power DC-to-DC converters

NASA Technical Reports Server (NTRS)

Wilson, T. G.; Owen, H. A., Jr.; Wilson, P. M.

1981-01-01

The current and voltage waveshapes associated with the power transitor and the power diode in an example current-or-voltage step-up (buck-boost) converter were analyzed to highlight the problems and possible tradeoffs involved in the design of high voltage high power converters operating at switching frequencies in the range of 100 Khz. Although the fast switching speeds of currently available power diodes and transistors permit converter operation at high switching frequencies, the resulting time rates of changes of current coupled with parasitic inductances in series with the semiconductor switches, produce large repetitive voltage transients across the semiconductor switches, potentially far in excess of the device voltage ratings. The need is established for semiconductor switch protection circuitry to control the peak voltages appearing across the semiconductor switches, as well as to provide the waveshaping action require for a given semiconductor device. The possible tradeoffs, as well as the factors affecting the tradeoffs that must be considered in order to maximize the efficiency of the converters are enumerated.

High frequency modal identification on noisy high-speed camera data

NASA Astrophysics Data System (ADS)

Javh, Jaka; Slavič, Janko; Boltežar, Miha

2018-01-01

Vibration measurements using optical full-field systems based on high-speed footage are typically heavily burdened by noise, as the displacement amplitudes of the vibrating structures are often very small (in the range of micrometers, depending on the structure). The modal information is troublesome to measure as the structure's response is close to, or below, the noise level of the camera-based measurement system. This paper demonstrates modal parameter identification for such noisy measurements. It is shown that by using the Least-Squares Complex-Frequency method combined with the Least-Squares Frequency-Domain method, identification at high-frequencies is still possible. By additionally incorporating a more precise sensor to identify the eigenvalues, a hybrid accelerometer/high-speed camera mode shape identification is possible even below the noise floor. An accelerometer measurement is used to identify the eigenvalues, while the camera measurement is used to produce the full-field mode shapes close to 10 kHz. The identified modal parameters improve the quality of the measured modal data and serve as a reduced model of the structure's dynamics.

Measures of extents of laterality for high-frequency ``transposed'' stimuli under conditions of binaural interference

NASA Astrophysics Data System (ADS)

Bernstein, Leslie R.; Trahiotis, Constantine

2005-09-01

Our purpose in this study was to determine whether across-frequency binaural interference would occur if ITD-based extents of laterality were measured using high-frequency transposed stimuli as targets. The results of an earlier study [L. R. Bernstein and C. Trahiotis, J. Acoust. Soc. Am. 116, 3062-3069 (2004)], which focused on threshold-ITDs, rather than extents of laterality, suggested that high-frequency transposed stimuli might be ``immune'' to binaural interference effects resulting from the addition of a spectrally remote, low-frequency interferer. In contrast to the earlier findings, the data from this study indicate that high-frequency transposed targets are susceptible to binaural interference. Nevertheless, high-frequency transposed targets, even when presented along with an interferer, yielded greater extents of ITD-based laterality than did high-frequency Gaussian noise targets presented in isolation. That is, the ``enhanced potency'' of ITDs conveyed by transposed stimuli persisted, even in the presence of a low-frequency interferer. Predictions made using an extension of the model of Heller and Trahiotis [L. M. Heller and C. Trahiotis, J. Acoust. Soc. Am. 99, 3632-3637 (1996)] accounted well for across-frequency binaural interference obtained with conventional Gaussian noise targets but, in all but one case, overpredicted the amounts of interference found with the transposed targets.

High frequency ultrasound imaging in pupillary block glaucoma.

PubMed Central

Aslanides, I M; Libre, P E; Silverman, R H; Reinstein, D Z; Lazzaro, D R; Rondeau, M J; Harmon, G K; Coleman, D J

1995-01-01

BACKGROUND--The diagnosis of pupillary block glaucoma requires sufficient clarity of the ocular media. This is particularly important for assessment of both the presence and patency of an iridotomy, and the determination of central anterior chamber depth. METHODS--High frequency ultrasonography was used in three patients with suspected pupillary block to determine iris configuration, posterior chamber volume, and ciliary body conformation. RESULTS--All patients demonstrated high frequency ultrasonographic findings consistent with pupillary block: iris bombé, a formed posterior chamber, and a lack of anterior rotation of the ciliary processes. CONCLUSION--High frequency ultrasound imaging appears to be a valuable adjunct in making or corroborating the diagnosis of pupillary block glaucoma. Images PMID:8534666

Myoneural necrosis following high-frequency electrical stimulation of the cast-immobilized rabbit hindlimb

NASA Technical Reports Server (NTRS)

Friden, J.; Lieber, R. L.; Myers, R. R.; Powell, H. C.; Hargens, A. R.

1989-01-01

The morphological and physiological effects of 4 weeks of high-frequency electrical stimulation (1 h/day, 5 days/week) on cast-immobilized rabbit hindlimbs were investigated in the tibialis anterior muscle and peroneal nerve. In 2 out of 6 animals, high-frequency stimulation with immobilization caused muscle fiber death, internalization of muscle fiber nuclei, connective tissue proliferation, inflammatory response, altered fiber size distribution and variable staining intensities. The fast-twitch fibers were predominantly affected. Two of six peripheral nerves subjected to immobilization and stimulation showed severe damage. Tetanic forces were significantly reduced in the affected muscles. Therefore, the immobilization and high-frequency stimulation may be detrimental to myoneural structure and function and, thus, this combination of therapies should be applied conservatively.

Compact high voltage, high peak power, high frequency transformer for converter type modulator applications.

PubMed

Reghu, T; Mandloi, V; Shrivastava, Purushottam

2016-04-01

The design and development of a compact high voltage, high peak power, high frequency transformer for a converter type modulator of klystron amplifiers is presented. The transformer has been designed to operate at a frequency of 20 kHz and at a flux swing of ±0.6 T. Iron (Fe) based nanocrystalline material has been selected as a core for the construction of the transformer. The transformer employs a specially designed solid Teflon bobbin having 120 kV insulation for winding the high voltage secondary windings. The flux swing of the core has been experimentally found by plotting the hysteresis loop at actual operating conditions. Based on the design, a prototype transformer has been built which is per se a unique combination of high voltage, high frequency, and peak power specifications. The transformer was able to provide 58 kV (pk-pk) at the secondary with a peak power handling capability of 700 kVA. The transformation ratio was 1:17. The performance of the transformer is also presented and discussed.

Scatterings and Quantum Effects in (Al ,In )N /GaN Heterostructures for High-Power and High-Frequency Electronics

NASA Astrophysics Data System (ADS)

Wang, Leizhi; Yin, Ming; Khan, Asif; Muhtadi, Sakib; Asif, Fatima; Choi, Eun Sang; Datta, Timir

2018-02-01

Charge transport in the wide-band-gap (Al ,In )N /GaN heterostructures with high carrier density approximately 2 ×1013 cm-2 is investigated over a large range of temperature (270 mK ≤T ≤280 K ) and magnetic field (0 ≤B ≤18 T ). We observe the first evidence of weak localization in the two-dimensional electron gas in this system. From the Shubnikov-de Haas (SdH) oscillations a relatively light effective mass of 0.23 me is determined. Furthermore, the linear dependence with temperature (T <20 K ) of the inelastic scattering rate (τi-1∝T ) is attributed to the phase breaking by electron-electron scattering. Also in the same temperature range the less-than unit ratio of quantum lifetime to Hall transport time (τq/τt<1 ) is taken to signify the dominance of small-angle scattering. Above 20 K, with increasing temperature scattering changes from acoustic phonon to optical phonon scattering, resulting in a rapid decrease in carrier mobility and increase in sheet resistance. Suppression of such scatterings will lead to higher mobility and a way forward to high-power and high-frequency electronics.

Improving mental task classification by adding high frequency band information.

PubMed

Zhang, Li; He, Wei; He, Chuanhong; Wang, Ping

2010-02-01

Features extracted from delta, theta, alpha, beta and gamma bands spanning low frequency range are commonly used to classify scalp-recorded electroencephalogram (EEG) for designing brain-computer interface (BCI) and higher frequencies are often neglected as noise. In this paper, we implemented an experimental validation to demonstrate that high frequency components could provide helpful information for improving the performance of the mental task based BCI. Electromyography (EMG) and electrooculography (EOG) artifacts were removed by using blind source separation (BSS) techniques. Frequency band powers and asymmetry ratios from the high frequency band (40-100 Hz) together with those from the lower frequency bands were used to represent EEG features. Finally, Fisher discriminant analysis (FDA) combining with Mahalanobis distance were used as the classifier. In this study, four types of classifications were performed using EEG signals recorded from four subjects during five mental tasks. We obtained significantly higher classification accuracy by adding the high frequency band features compared to using the low frequency bands alone, which demonstrated that the information in high frequency components from scalp-recorded EEG is valuable for the mental task based BCI.

Time-frequency representation of a highly nonstationary signal via the modified Wigner distribution

NASA Technical Reports Server (NTRS)

Zoladz, T. F.; Jones, J. H.; Jong, J.

1992-01-01

A new signal analysis technique called the modified Wigner distribution (MWD) is presented. The new signal processing tool has been very successful in determining time frequency representations of highly non-stationary multicomponent signals in both simulations and trials involving actual Space Shuttle Main Engine (SSME) high frequency data. The MWD departs from the classic Wigner distribution (WD) in that it effectively eliminates the cross coupling among positive frequency components in a multiple component signal. This attribute of the MWD, which prevents the generation of 'phantom' spectral peaks, will undoubtedly increase the utility of the WD for real world signal analysis applications which more often than not involve multicomponent signals.

Quality ratings of frequency-compressed speech by participants with extensive high-frequency dead regions in the cochlea

PubMed Central

Salorio-Corbetto, Marina; Baer, Thomas; Moore, Brian C. J.

2017-01-01

Abstract Objective: The objective was to assess the degradation of speech sound quality produced by frequency compression for listeners with extensive high-frequency dead regions (DRs). Design: Quality ratings were obtained using values of the starting frequency (Sf) of the frequency compression both below and above the estimated edge frequency, fe, of each DR. Thus, the value of Sf often fell below the lowest value currently used in clinical practice. Several compression ratios were used for each value of Sf. Stimuli were sentences processed via a prototype hearing aid based on Phonak Exélia Art P. Study sample: Five participants (eight ears) with extensive high-frequency DRs were tested. Results: Reductions of sound-quality produced by frequency compression were small to moderate. Ratings decreased significantly with decreasing Sf and increasing CR. The mean ratings were lowest for the lowest Sf and highest CR. Ratings varied across participants, with one participant rating frequency compression lower than no frequency compression even when Sf was above fe. Conclusions: Frequency compression degraded sound quality somewhat for this small group of participants with extensive high-frequency DRs. The degradation was greater for lower values of Sf relative to fe, and for greater values of CR. Results varied across participants. PMID:27724057

High-frequency ultrasound for monitoring changes in liver tissue during preservation

NASA Astrophysics Data System (ADS)

Vlad, Roxana M.; Czarnota, Gregory J.; Giles, Anoja; Sherar, Michael D.; Hunt, John W.; Kolios, Michael C.

2005-01-01

Currently the only method to assess liver preservation injury is based on liver appearance and donor medical history. Previous work has shown that high-frequency ultrasound could detect ischemic cell death due to changes in cell morphology. In this study, we use high-frequency ultrasound integrated backscatter to assess liver damage in experimental models of liver ischemia. Ultimately, our goal is to predict organ suitability for transplantation using high-frequency imaging and spectral analysis techniques. To examine the effects of liver ischemia at different temperatures, livers from Wistar rats were surgically excised, immersed in phosphate buffer saline and stored at 4 and 20 °C for 24 h. To mimic organ preservation, livers were excised, flushed with University of Wisconsin (UW) solution and stored at 4 °C for 24 h. Preservation injury was simulated by either not flushing livers with UW solution or, before scanning, allowing livers to reach room temperature. Ultrasound images and corresponding radiofrequency data were collected over the ischemic period. No significant increase in integrated backscatter (~2.5 dBr) was measured for the livers prepared using standard preservation conditions. For all other ischemia models, the integrated backscatter increased by 4-9 dBr demonstrating kinetics dependent on storage conditions. The results provide a possible framework for using high-frequency imaging to non-invasively assess liver preservation injury.

Disordered high-frequency oscillation in face processing in schizophrenia patients

PubMed Central

Liu, Miaomiao; Pei, Guangying; Peng, Yinuo; Wang, Changming; Yan, Tianyi; Wu, Jinglong

2018-01-01

Abstract Schizophrenia is a complex disorder characterized by marked social dysfunctions, but the neural mechanism underlying this deficit is unknown. To investigate whether face-specific perceptual processes are influenced in schizophrenia patients, both face detection and configural analysis were assessed in normal individuals and schizophrenia patients by recording electroencephalogram (EEG) data. Here, a face processing model was built based on the frequency oscillations, and the evoked power (theta, alpha, and beta bands) and the induced power (gamma bands) were recorded while the subjects passively viewed face and nonface images presented in upright and inverted orientations. The healthy adults showed a significant face-specific effect in the alpha, beta, and gamma bands, and an inversion effect was observed in the gamma band in the occipital lobe and right temporal lobe. Importantly, the schizophrenia patients showed face-specific deficits in the low-frequency beta and gamma bands, and the face inversion effect in the gamma band was absent from the occipital lobe. All these results revealed face-specific processing in patients due to the disorder of high-frequency EEG, providing additional evidence to enrich future studies investigating neural mechanisms and serving as a marked diagnostic basis. PMID:29419668

High frequency power distribution system

NASA Technical Reports Server (NTRS)

Patel, Mikund R.

1986-01-01

The objective of this project was to provide the technology of high frequency, high power transmission lines to the 100 kW power range at 20 kHz frequency. In addition to the necessary design studies, a 150 m long, 600 V, 60 A transmission line was built, tested and delivered for full vacuum tests. The configuration analysis on five alternative configurations resulted in the final selection of the three parallel Litz straps configuration, which gave a virtually concentric design in the electromagnetic sense. Low inductance, low EMI and flexibility in handling are the key features of this configuration. The final design was made after a parametric study to minimize the losses, weight and inductance. The construction of the cable was completed with no major difficulties. The R,L,C parameters measured on the cable agreed well with the calculated values. The corona tests on insulation samples showed a safety factor of 3.

Exfoliated BN shell-based high-frequency magnetic core-shell materials.

PubMed

Zhang, Wei; Patel, Ketan; Ren, Shenqiang

2017-09-14

The miniaturization of electric machines demands high frequency magnetic materials with large magnetic-flux density and low energy loss to achieve a decreased dimension of high rotational speed motors. Herein, we report a solution-processed high frequency magnetic composite (containing a nanometal FeCo core and a boron nitride (BN) shell) that simultaneously exhibits high electrical resistivity and magnetic permeability. The frequency dependent complex initial permeability and the mechanical robustness of nanocomposites are intensely dependent on the content of BN insulating phase. The results shown here suggest that insulating magnetic nanocomposites have potential for application in next-generation high-frequency electric machines with large electrical resistivity and permeability.

A High Power Frequency Doubled Fiber Laser

NASA Technical Reports Server (NTRS)

Thompson, Robert J.; Tu, Meirong; Aveline, Dave; Lundblad, Nathan; Maleki, Lute

2003-01-01

This viewgraph presentation reports on the development of a high power 780 nm laser suitable for space applications of laser cooling. A possible solution is to use frequency doubling of high power 1560 nm telecom lasers. The presentation shows a diagram of the frequency conversion, and a graph of the second harmonic generation in one crystal, and the use of the cascading crystals. Graphs show the second harmonic power as a function of distance between crystals, second harmonic power vs. pump power, tunability of laser systems.

Ionospheric modifications in high frequency heating experiments

NASA Astrophysics Data System (ADS)

Kuo, Spencer P.

2015-01-01

Featured observations in high-frequency (HF) heating experiments conducted at Arecibo, EISCAT, and high frequency active auroral research program are discussed. These phenomena appearing in the F region of the ionosphere include high-frequency heater enhanced plasma lines, airglow enhancement, energetic electron flux, artificial ionization layers, artificial spread-F, ionization enhancement, artificial cusp, wideband absorption, short-scale (meters) density irregularities, and stimulated electromagnetic emissions, which were observed when the O-mode HF heater waves with frequencies below foF2 were applied. The implication and associated physical mechanism of each observation are discussed and explained. It is shown that these phenomena caused by the HF heating are all ascribed directly or indirectly to the excitation of parametric instabilities which instigate anomalous heating. Formulation and analysis of parametric instabilities are presented. The results show that oscillating two stream instability and parametric decay instability can be excited by the O-mode HF heater waves, transmitted from all three heating facilities, in the regions near the HF reflection height and near the upper hybrid resonance layer. The excited Langmuir waves, upper hybrid waves, ion acoustic waves, lower hybrid waves, and field-aligned density irregularities set off subsequent wave-wave and wave-electron interactions, giving rise to the observed phenomena.

Vast Volatility Matrix Estimation using High Frequency Data for Portfolio Selection*

PubMed Central

Fan, Jianqing; Li, Yingying; Yu, Ke

2012-01-01

Portfolio allocation with gross-exposure constraint is an effective method to increase the efficiency and stability of portfolios selection among a vast pool of assets, as demonstrated in Fan et al. (2011). The required high-dimensional volatility matrix can be estimated by using high frequency financial data. This enables us to better adapt to the local volatilities and local correlations among vast number of assets and to increase significantly the sample size for estimating the volatility matrix. This paper studies the volatility matrix estimation using high-dimensional high-frequency data from the perspective of portfolio selection. Specifically, we propose the use of “pairwise-refresh time” and “all-refresh time” methods based on the concept of “refresh time” proposed by Barndorff-Nielsen et al. (2008) for estimation of vast covariance matrix and compare their merits in the portfolio selection. We establish the concentration inequalities of the estimates, which guarantee desirable properties of the estimated volatility matrix in vast asset allocation with gross exposure constraints. Extensive numerical studies are made via carefully designed simulations. Comparing with the methods based on low frequency daily data, our methods can capture the most recent trend of the time varying volatility and correlation, hence provide more accurate guidance for the portfolio allocation in the next time period. The advantage of using high-frequency data is significant in our simulation and empirical studies, which consist of 50 simulated assets and 30 constituent stocks of Dow Jones Industrial Average index. PMID:23264708

Quality properties of pre- and post-rigor beef muscle after interventions with high frequency ultrasound.

PubMed

Sikes, Anita L; Mawson, Raymond; Stark, Janet; Warner, Robyn

2014-11-01

The delivery of a consistent quality product to the consumer is vitally important for the food industry. The aim of this study was to investigate the potential for using high frequency ultrasound applied to pre- and post-rigor beef muscle on the metabolism and subsequent quality. High frequency ultrasound (600kHz at 48kPa and 65kPa acoustic pressure) applied to post-rigor beef striploin steaks resulted in no significant effect on the texture (peak force value) of cooked steaks as measured by a Tenderometer. There was no added benefit of ultrasound treatment above that of the normal ageing process after ageing of the steaks for 7days at 4°C. Ultrasound treatment of post-rigor beef steaks resulted in a darkening of fresh steaks but after ageing for 7days at 4°C, the ultrasound-treated steaks were similar in colour to that of the aged, untreated steaks. High frequency ultrasound (2MHz at 48kPa acoustic pressure) applied to pre-rigor beef neck muscle had no effect on the pH, but the calculated exhaustion factor suggested that there was some effect on metabolism and actin-myosin interaction. However, the resultant texture of cooked, ultrasound-treated muscle was lower in tenderness compared to the control sample. After ageing for 3weeks at 0°C, the ultrasound-treated samples had the same peak force value as the control. High frequency ultrasound had no significant effect on the colour parameters of pre-rigor beef neck muscle. This proof-of-concept study showed no effect of ultrasound on quality but did indicate that the application of high frequency ultrasound to pre-rigor beef muscle shows potential for modifying ATP turnover and further investigation is warranted. Crown Copyright © 2014. Published by Elsevier B.V. All rights reserved.

Multi-frequency inversion-charge pumping for charge separation and mobility analysis in high-k/InGaAs metal-oxide-semiconductor field-effect transistors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Djara, V.; Cherkaoui, K.; Negara, M. A.

2015-11-28

An alternative multi-frequency inversion-charge pumping (MFICP) technique was developed to directly separate the inversion charge density (N{sub inv}) from the trapped charge density in high-k/InGaAs metal-oxide-semiconductor field-effect transistors (MOSFETs). This approach relies on the fitting of the frequency response of border traps, obtained from inversion-charge pumping measurements performed over a wide range of frequencies at room temperature on a single MOSFET, using a modified charge trapping model. The obtained model yielded the capture time constant and density of border traps located at energy levels aligned with the InGaAs conduction band. Moreover, the combination of MFICP and pulsed I{sub d}-V{sub g}more » measurements enabled an accurate effective mobility vs N{sub inv} extraction and analysis. The data obtained using the MFICP approach are consistent with the most recent reports on high-k/InGaAs.« less

Effect of Y2O3 on polyindole for high frequency capacitor application

NASA Astrophysics Data System (ADS)

Maji, P.; Choudhary, R. B.; Majhi, M.

2017-05-01

Polyindole-Yittrium Oxide (PIn-Y2O3) composite was synthesized in the laboratory through chemical polymerization process. The structural and morphological studies of PIn-Y2O3 composite were investigated using X-ray diffraction (XRD) and scanning electron microscopic (SEM) techniques. These studies showed that PIn-Y2O3 composite was amorphous in nature and formed with spherical granule shape. The dielectric response was measured through LCR meter in the frequency range from 100 Hz to 1 MHz. The dielectric studies revealed that incorporation of Y2O3 into polymeric matrix improved the dielectric behavior of PIn polymer and markedly suitable for its application in high frequency capacitor and many other electronic devices.

Recognition memory for low- and high-frequency-filtered emotional faces: Low spatial frequencies drive emotional memory enhancement, whereas high spatial frequencies drive the emotion-induced recognition bias.

PubMed

Rohr, Michaela; Tröger, Johannes; Michely, Nils; Uhde, Alarith; Wentura, Dirk

2017-07-01

This article deals with two well-documented phenomena regarding emotional stimuli: emotional memory enhancement-that is, better long-term memory for emotional than for neutral stimuli-and the emotion-induced recognition bias-that is, a more liberal response criterion for emotional than for neutral stimuli. Studies on visual emotion perception and attention suggest that emotion-related processes can be modulated by means of spatial-frequency filtering of the presented emotional stimuli. Specifically, low spatial frequencies are assumed to play a primary role for the influence of emotion on attention and judgment. Given this theoretical background, we investigated whether spatial-frequency filtering also impacts (1) the memory advantage for emotional faces and (2) the emotion-induced recognition bias, in a series of old/new recognition experiments. Participants completed incidental-learning tasks with high- (HSF) and low- (LSF) spatial-frequency-filtered emotional and neutral faces. The results of the surprise recognition tests showed a clear memory advantage for emotional stimuli. Most importantly, the emotional memory enhancement was significantly larger for face images containing only low-frequency information (LSF faces) than for HSF faces across all experiments, suggesting that LSF information plays a critical role in this effect, whereas the emotion-induced recognition bias was found only for HSF stimuli. We discuss our findings in terms of both the traditional account of different processing pathways for HSF and LSF information and a stimulus features account. The double dissociation in the results favors the latter account-that is, an explanation in terms of differences in the characteristics of HSF and LSF stimuli.

When ottoman is easier than chair: an inverse frequency effect in jargon aphasia.

PubMed

Marshall, J; Pring, T; Chiat, S; Robson, J

2001-02-01

This paper presents evidence of an inverse frequency effect in jargon aphasia. The subject (JP) showed a pre-disposition for low frequency word production on a range of tasks, including picture naming, sentence completion and naming in categories. Her real word errors were also striking, in that these tended to be lower in frequency than the target. Reading data suggested that the inverse frequency effect was present only when production was semantically mediated. It was therefore hypothesised that the effect was at least partly due to the semantic characteristics of low frequency items. Some support for this was obtained from a comprehension task showing that JP's understanding of low frequency terms, which she often produced as errors, was superior to her understanding of high frequency terms. Possible explanations for these findings are considered.

Effects of dosage and dosing frequency on the efficacy and safety of high-dose metformin in Japanese patients with type 2 diabetes mellitus.

PubMed

Kanto, Kousei; Ito, Hiroyuki; Noso, Shinsuke; Babaya, Naru; Hiromine, Yoshihisa; Taketomo, Yasunori; Toma, Junko; Niwano, Fumimaru; Yasutake, Sara; Kawabata, Yumiko; Ikegami, Hiroshi

2017-09-30

Differences in the efficacy and safety of antidiabetic drugs among different ethnic groups are well documented. Metformin is widely used in the treatment of type 2 diabetes in Western countries, but high doses of metformin have been approved only recently for clinical use in Japan. The aim of the present study was to investigate the effects of dosage and dosing frequency on the efficacy and safety of high-dose metformin in Japanese patients. A total of 71 Japanese patients with type 2 diabetes were prospectively studied for the effects of dosage and dosing frequency on the efficacy and safety of metformin during hospitalization. Dose effects were studied in 27 patients treated with 0, 500, 1,000, 1,500 and 2,250 mg/day of metformin. The effect of dosing frequency was compared in 56 patients with 1,500 mg/day of metformin administered either two or three times per day. Significant dose-dependent improvement in daily profiles of blood glucose was observed with metformin dosages up to 1,500 mg/day, with a trend towards further improvement observed at 2,250 mg/day. The efficacy of 1,500 mg of metformin was comparable when the drug was administered either two or three times per day. The most frequently reported side-effects were gastrointestinal symptoms, which were not affected by the dosage or dosing frequency of metformin. These results show that the efficacy of high-dose metformin is dose-dependent in Japanese patients. The efficacy and safety of metformin were similar when the drug was administered either two or three times per day. © 2017 The Authors. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, Ltd.

Gender and vocal production mode discrimination using the high frequencies for speech and singing

PubMed Central

Monson, Brian B.; Lotto, Andrew J.; Story, Brad H.

2014-01-01

Humans routinely produce acoustical energy at frequencies above 6 kHz during vocalization, but this frequency range is often not represented in communication devices and speech perception research. Recent advancements toward high-definition (HD) voice and extended bandwidth hearing aids have increased the interest in the high frequencies. The potential perceptual information provided by high-frequency energy (HFE) is not well characterized. We found that humans can accomplish tasks of gender discrimination and vocal production mode discrimination (speech vs. singing) when presented with acoustic stimuli containing only HFE at both amplified and normal levels. Performance in these tasks was robust in the presence of low-frequency masking noise. No substantial learning effect was observed. Listeners also were able to identify the sung and spoken text (excerpts from “The Star-Spangled Banner”) with very few exposures. These results add to the increasing evidence that the high frequencies provide at least redundant information about the vocal signal, suggesting that its representation in communication devices (e.g., cell phones, hearing aids, and cochlear implants) and speech/voice synthesizers could improve these devices and benefit normal-hearing and hearing-impaired listeners. PMID:25400613

A study of the high-frequency hearing thresholds of dentistry professionals

PubMed Central

Lopes, Andréa Cintra; de Melo, Ana Dolores Passarelli; Santos, Cibele Carmelo

2012-01-01

Summary Introduction: In the dentistry practice, dentists are exposed to harmful effects caused by several factors, such as the noise produced by their work instruments. In 1959, the American Dental Association recommended periodical hearing assessments and the use of ear protectors. Aquiring more information regarding dentists', dental nurses', and prosthodontists' hearing abilities is necessary to propose prevention measures and early treatment strategies. Objective: To investigate the auditory thresholds of dentists, dental nurses, and prosthodontists. Method: In this clinical and experimental study, 44 dentists (Group I; GI), 36 dental nurses (Group II; GII), and 28 prosthodontists (Group III; GIII) were included, , with a total of 108 professionals. The procedures that were performed included a specific interview, ear canal inspection, conventional and high-frequency threshold audiometry, a speech reception threshold test, and an acoustic impedance test. Results: In the 3 groups that were tested, the comparison between the mean hearing thresholds provided evidence of worsened hearing ability relative to the increase in frequency. For the tritonal mean at 500 to 2,000 Hz and 3,000 to 6,000 Hz, GIII presented the worst thresholds. For the mean of the high frequencies (9,000 and 16,000 Hz), GII presented the worst thresholds. Conclusion: The conventional hearing threshold evaluation did not demonstrate alterations in the 3 groups that were tested; however, the complementary tests such as high-frequency audiometry provided greater efficacy in the early detection of hearing problems, since this population's hearing loss impaired hearing ability at frequencies that are not tested by the conventional tests. Therefore, we emphasize the need of utilizing high-frequency threshold audiometry in the hearing assessment routine in combination with other audiological tests. PMID:25991940

Quantitative methods for stochastic high frequency spatio-temporal and non-linear analysis: Assessing health effects of exposure to extreme ambient temperature

NASA Astrophysics Data System (ADS)

Liss, Alexander

Extreme weather events, such as heat waves and cold spells, cause substantial excess mortality and morbidity in the vulnerable elderly population, and cost billions of dollars. The accurate and reliable assessment of adverse effects of extreme weather events on human health is crucial for environmental scientists, economists, and public health officials to ensure proper protection of vulnerable populations and efficient allocation of scarce resources. However, the methodology for the analysis of large national databases is yet to be developed. The overarching objective of this dissertation is to examine the effect of extreme weather on the elderly population of the Conterminous US (ConUS) with respect to seasonality in temperature in different climatic regions by utilizing heterogeneous high frequency and spatio-temporal resolution data. To achieve these goals the author: 1) incorporated dissimilar stochastic high frequency big data streams and distinct data types into the integrated data base for use in analytical and decision support frameworks; 2) created an automated climate regionalization system based on remote sensing and machine learning to define climate regions for the Conterminous US; 3) systematically surveyed the current state of the art and identified existing gaps in the scientific knowledge; 4) assessed the dose-response relationship of exposure to temperature extremes on human health in relatively homogeneous climate regions using different statistical models, such as parametric and non-parametric, contemporaneous and asynchronous, applied to the same data; 5) assessed seasonal peak timing and synchronization delay of the exposure and the disease within the framework of contemporaneous high frequency harmonic time series analysis and modification of the effect by the regional climate; 6) modeled using hyperbolic functional form non-linear properties of the effect of exposure to extreme temperature on human health. The proposed climate

Noninvasive Diagnosis of Coronary Artery Disease Using 12-Lead High-Frequency Electrocardiograms

NASA Technical Reports Server (NTRS)

Schlegel, Todd T.; Arenare, Brian

2006-01-01

A noninvasive, sensitive method of diagnosing certain pathological conditions of the human heart involves computational processing of digitized electrocardiographic (ECG) signals acquired from a patient at all 12 conventional ECG electrode positions. In the processing, attention is focused on low-amplitude, high-frequency components of those portions of the ECG signals known in the art as QRS complexes. The unique contribution of this method lies in the utilization of signal features and combinations of signal features from various combinations of electrode positions, not reported previously, that have been found to be helpful in diagnosing coronary artery disease and such related pathological conditions as myocardial ischemia, myocardial infarction, and congestive heart failure. The electronic hardware and software used to acquire the QRS complexes and perform some preliminary analyses of their high-frequency components were summarized in Real-Time, High-Frequency QRS Electrocardiograph (MSC- 23154), NASA Tech Briefs, Vol. 27, No. 7 (July 2003), pp. 26-28. To recapitulate, signals from standard electrocardiograph electrodes are preamplified, then digitized at a sampling rate of 1,000 Hz, then analyzed by the software that detects R waves and QRS complexes and analyzes them from several perspectives. The software includes provisions for averaging signals over multiple beats and for special-purpose nonrecursive digital filters with specific low- and high-frequency cutoffs. These filters, applied to the averaged signal, effect a band-pass operation in the frequency range from 150 to 250 Hz. The output of the bandpass filter is the desired high-frequency QRS signal. Further processing is then performed in real time to obtain the beat-to-beat root mean square (RMS) voltage amplitude of the filtered signal, certain variations of the RMS voltage, and such standard measures as the heart rate and R-R interval at any given time. A key signal feature analyzed in the present

Simple method enabling pulse on command from high power, high frequency lasers

NASA Astrophysics Data System (ADS)

Baer, David J.; Marshall, Graham D.; Coutts, David W.; Mildren, Richard P.; Withford, Michael J.

2006-09-01

A method for addressing individual laser pulses in high repetition frequency systems using an intracavity optical chopper and novel electronic timing system is reported. This "pulse on command" capability is shown to enable free running and both subharmonic pulse rate and burst mode operation of a high power, high pulse frequency copper vapor laser while maintaining a fixed output pulse energy. We demonstrate that this technique can be used to improve feature finish when laser micromachining metal.

Nasal high-frequency oscillatory ventilation impairs heated humidification: A neonatal bench study.

PubMed

Ullrich, Tim L; Czernik, Christoph; Bührer, Christoph; Schmalisch, Gerd; Fischer, Hendrik S

2017-11-01

Nasal high-frequency oscillatory ventilation (nHFOV) is a novel mode of non-invasive ventilation used in neonates. However, upper airway obstructions due to viscous secretions have been described as specific adverse effects. We hypothesized that high-frequency oscillations reduce air humidity in the oropharynx, resulting in upper airway desiccation. Therefore, we aimed to investigate the effects of nHFOV ventilatory settings on oropharyngeal gas conditions. NHFOV or nasal continuous positive airway pressure (nCPAP) was applied, along with heated humidification, to a previously established neonatal bench model that simulates oropharyngeal gas conditions during spontaneous breathing through an open mouth. A digital thermo-hygro sensor measured oropharyngeal temperature (T) and humidity at various nHFOV frequencies (7, 10, 13 Hz), amplitudes (10, 20, 30 cmH 2 O), and inspiratory-to-expiratory (I:E) ratios (25:75, 33:66, 50:50), and also during nCPAP. Relative humidity was always >99%, but nHFOV resulted in lower mean T and absolute humidity (AH) in comparison to nCPAP (P < 0.001). Specifically, decreasing the nHFOV frequency and increasing nHFOV amplitude caused a decline in T and AH (P < 0.001). Mean T and AH were highest during nCPAP (T 34.8 ± 0.6°C, AH 39.3 ± 1.3 g · m -3 ) and lowest during nHFOV at a frequency of 7 Hz and an amplitude of 30 cmH 2 O (T 32.4 ± 0.3°C, AH 34.7 ± 0.5 g · m -3 ). Increasing the I:E ratio also reduced T and AH (P = 0.03). Intensified nHFOV settings with low frequencies, high amplitudes, and high I:E ratios may place infants at an increased risk of upper airway desiccation. Future studies should investigate strategies to optimize heated humidification during nHFOV. © 2017 Wiley Periodicals, Inc.

[A Feasibility Study of closing the small bowel with high-frequency welding device].

PubMed

Zhou, Huabin; Han, Shuai; Chen, Jun; Huang, Dequn; Peng, Liang; Ning, Jingxuan; Li, Zhou

2014-12-01

This study aimed to evaluate the feasibility and effectiveness of closing the small bowel in an ex vivo porcine model with high-frequency welding device. A total of 100 porcine small bowels were divided into two groups, and then were closed with two different methods. The fifty small bowels in experimental group were closed by the high-frequency welding device, and the other fifty small bowels in comparison group were hand-sutured. All the small bowels were subjected to leak pressure testing later on. The speed of closure and bursting pressure were compared. The 50 porcine small bowels closed by the high-frequency welding device showed a success rate of 100%. Compared with the hand-sutured group, the bursting pressures of the former were significantly lower (P<0.01) and the closing process was significantly shorter (P<0.01). The pathological changes of the closed ends mainly presented as acute thermal and pressure induced injury. Experimental results show that the high-frequency welding device has higher feasibility in closing the small bowel.

Using high-frequency sampling to detect effects of atmospheric pollutants on stream chemistry

Treesearch

Stephen D. Sebestyen; James B. Shanley; Elizabeth W. Boyer

2009-01-01

We combined information from long-term (weekly over many years) and short-term (high-frequency during rainfall and snowmelt events) stream water sampling efforts to understand how atmospheric deposition affects stream chemistry. Water samples were collected at the Sleepers River Research Watershed, VT, a temperate upland forest site that receives elevated atmospheric...

Extracting cardiac myofiber orientations from high frequency ultrasound images

NASA Astrophysics Data System (ADS)

Qin, Xulei; Cong, Zhibin; Jiang, Rong; Shen, Ming; Wagner, Mary B.; Kirshbom, Paul; Fei, Baowei

2013-03-01

Cardiac myofiber plays an important role in stress mechanism during heart beating periods. The orientation of myofibers decides the effects of the stress distribution and the whole heart deformation. It is important to image and quantitatively extract these orientations for understanding the cardiac physiological and pathological mechanism and for diagnosis of chronic diseases. Ultrasound has been wildly used in cardiac diagnosis because of its ability of performing dynamic and noninvasive imaging and because of its low cost. An extraction method is proposed to automatically detect the cardiac myofiber orientations from high frequency ultrasound images. First, heart walls containing myofibers are imaged by B-mode high frequency (<20 MHz) ultrasound imaging. Second, myofiber orientations are extracted from ultrasound images using the proposed method that combines a nonlinear anisotropic diffusion filter, Canny edge detector, Hough transform, and K-means clustering. This method is validated by the results of ultrasound data from phantoms and pig hearts.

Comparison of electroacupuncture frequency-related effects on heart rate variability in healthy volunteers: a randomized clinical trial.

PubMed

Lee, Jong-Ho; Kim, Kyu-Hyeong; Hong, Jin-Woo; Lee, Won-Chul; Koo, Sungtae

2011-06-01

This study aimed to compare the effects of high frequency electroacupuncture (EA) and low-frequency EA on the autonomic nervous system by using a heart rate variability measuring device in normal individuals. Fourteen participants were recruited and each participated in the high-frequency and low-frequency sessions (crossover design). The order of sessions was randomized and the interval between the two sessions was over 2 weeks. Participants received needle insertion with 120-Hz stimulation during the high-frequency session (high-frequency EA group), and with 2-Hz stimulation during the low-frequency session (low-frequency EA group). Acupuncture needles were directly inserted perpendicularly to LI 4 and LI 11 acupoints followed by delivery of electric pulses to these points for 15 minutes. Heart rate variability was measured 5 minutes before and after EA stimulation by a heart rate variability measuring system. We found a significant increase in the standard deviation of the normal-to-normal interval in the high-frequency EA group, with no change in the low-frequency EA group. Both the high-frequency and low-frequency EA groups showed no significant differences in other parameters including high-frequency power, low-frequency power, and the ratio of low-frequency power to high-frequency power. Based on these findings, we concluded that high-frequency EA stimulation is more effective than low-frequency EA stimulation in increasing autonomic nervous activity and there is no difference between the two EA frequencies in enhancing sympathovagal balance. Copyright © 2011 Korean Pharmacopuncture Institute. Published by .. All rights reserved.

Effective switching frequency multiplier inverter

DOEpatents

Su, Gui-Jia [Oak Ridge, TN; Peng, Fang Z [Okemos, MI

2007-08-07

A switching frequency multiplier inverter for low inductance machines that uses parallel connection of switches and each switch is independently controlled according to a pulse width modulation scheme. The effective switching frequency is multiplied by the number of switches connected in parallel while each individual switch operates within its limit of switching frequency. This technique can also be used for other power converters such as DC/DC, AC/DC converters.

Effects of high-frequency near-infrared diode laser irradiation on the proliferation and migration of mouse calvarial osteoblasts.

PubMed

Kunimatsu, Ryo; Gunji, Hidemi; Tsuka, Yuji; Yoshimi, Yuki; Awada, Tetsuya; Sumi, Keisuke; Nakajima, Kengo; Kimura, Aya; Hiraki, Tomoka; Abe, Takaharu; Naoto, Hirose; Yanoshita, Makoto; Tanimoto, Kotaro

2018-07-01

Laser irradiation activates a range of cellular processes and can promote tissue repair. Here, we examined the effects of high-frequency near-infrared (NIR) diode laser irradiation on the proliferation and migration of mouse calvarial osteoblastic cells (MC3T3-E1). MC3T3-E1 cells were cultured and exposed to high-frequency (30 kHz) 910-nm diode laser irradiation at a dose of 0, 1.42, 2.85, 5.7, or 17.1 J/cm 2 . Cell proliferation was evaluated with BrdU and ATP concentration assays. Cell migration was analyzed by quantitative assessment of wound healing using the Incucyt ® ZOOM system. In addition, phosphorylation of mitogen-activated protein kinase (MAPK) family members including p38 mitogen-activated protein kinase (p38), stress-activated protein kinase/Jun-amino-terminal kinase (SAPK/JNK), and extracellular signal-regulated protein kinase (ERK)1/2) after laser irradiation was examined with western blotting. Compared to the control, cell proliferation was significantly increased by laser irradiation at a dose of 2.85, 5.7, or 17.1 J/cm 2 . Laser irradiation at a dose of 2.85 J/cm 2 induced MC3T3-E1 cells to migrate more rapidly than non-irradiated control cells. Irradiation with the high-frequency 910-nm diode laser at a dose of 2.85 J/cm 2 induced phosphorylation of MAPK/ERK1/2 15 and 30 min later. However, phosphorylation of p38 MAPK and SAPK/JNK was not changed by NIR diode laser irradiation at a dose of 2.85 J/cm 2 . Irradiation with a high-frequency NIR diode laser increased cell division and migration of MT3T3-E1 cells, possibly via MAPK/ERK signaling. These observations may be important for enhancing proliferation and migration of osteoblasts to improve regeneration of bone tissues.

Modeling high-frequency electromotility of cochlear outer hair cell in microchamber experiment.

PubMed

Liao, Zhijie; Popel, Aleksander S; Brownell, William E; Spector, Alexander A

2005-04-01

Cochlear outer hair cells (OHC) are critically important for the amplification and sharp frequency selectivity of the mammalian ear. The microchamber experiment has been an effective tool to analyze the OHC high-frequency performance. In this study, the OHC electrical stimulation in the microchamber is simulated. The model takes into account the inertial and viscous properties of fluids inside and outside the cell as well as the viscoelastic and piezoelectric properties of the cell composite membrane (wall). The closed ends of the cylindrical cell were considered as oscillatory rigid plates. The final solution was obtained in terms of Fourier series, and it was checked against the available results of the microchamber experiment. The conditions of the interaction between the cell and pipette was analyzed, and it was found that the amount of slip along the contact surface has a significant effect on the cell electromotile response. The cell's length changes were computed as a function of frequency, and their dependence on the viscosities of both fluids and the cell wall was analyzed. The distribution of the viscous losses inside the fluids was also estimated. The proposed approach can help in a better understanding of the high-frequency OHC electromotility under experimental and physiological conditions.

High relative frequency of SCA1 in Poland reflecting a potential founder effect.

PubMed

Krysa, Wioletta; Sulek, Anna; Rakowicz, Maria; Szirkowiec, Walentyna; Zaremba, Jacek

2016-08-01

Spinocerebellar ataxias (SCAs) have irregular distributions worldwide. SCA1 is the most frequent in Poland, and no cases of SCA3 of Polish origin has yet been identified. In view of such patterns of SCAs occurrence, the relative frequency, geographical distribution and a possible founder effect of SCA1 were investigated. DNA samples of 134 probands with SCA1 and 228 controls were analysed. The genotyping of four markers, D6S89, D6S109, D6S274, D6S288, around the ATXN1 gene (SCA1) and sequencing of the selected variant of D6S89 were performed. The relative frequency of SCA1 was 68 %. The studied SCA1 pedigrees were irregularly distributed, with the highest concentration in Central Poland. Haplotyping revealed the association of ATXN1 gene mutation with a 197-bp variant of D6S89 marker (63 % of probands) and with a 184-bp variant of DS6274 (50.7 % of probands). Out of 61 SCA1 probands from Mazowieckie, 41 carried the same 197-bp variant. SCA1 relative frequency in Poland shows the highest value compared with the data from other countries worldwide. Due to the association with the mutation obtained for the investigated markers and the SCA1 pedigrees concentration in Central Poland, we hypothesise that it represents a potential founder effect.

The Global Precipitation Measurement (GPM) Mission: Overview and Status

NASA Technical Reports Server (NTRS)

Hou, Arthur

2008-01-01

The Global Precipitation Measurement (GPM) Mission is an international satellite mission to unify and advance global precipitation measurements from a constellation of dedicated and operational microwave sensors. The GPM concept centers on the deployment of a Core Spacecraft in a non-Sun-synchronous orbit at 65 degrees inclination carrying a dual-frequency precipitation radar (DPR) and a multi-frequency passive microwave radiometer (GMI) with high-frequency capabilities to serve as a precipitation physics observatory and calibration standard for the constellation radiometers. The baseline GPM constellation is envisioned to comprise conical-scanning microwave imagers (e.g., GMI, SSMIS, AMSR, MIS, MADRAS, GPM-Brazil) augmented with cross-track microwave temperature/humidity sounders (e.g., MHS, ATMS) over land. In addition to the Core Satellite, the GPM Mission will contribute a second GMI to be flown in a low-inclination (approximately 40 deg.) non-Sun-synchronous orbit to improve near real-time monitoring of hurricanes. GPM is a science mission with integrated applications goals aimed at (1) advancing the knowledge of the global water/energy cycle variability and freshwater availability and (2) improving weather, climate, and hydrological prediction capabilities through more accurate and frequent measurements of global precipitation. The GPM Mission is currently a partnership between NASA and the Japan Aerospace Exploration Agency (JAXA), with opportunities for additional partners in satellite constellation and ground validation activities. Within the framework of the inter-governmental Group ob Earth Observations (GEO) and Global Earth Observation System of Systems (GEOSS), GPM has been identified as a cornerstone for the Precipitation Constellation (PC) being developed under the auspices of Committee of Earth Observation Satellites (CEOS). The GPM Core Observatory is scheduled for launch in 2013, followed by the launch of the GPM Low-Inclination Observatory in

High precision spectroscopy and imaging in THz frequency range

NASA Astrophysics Data System (ADS)

Vaks, Vladimir L.

2014-03-01

Application of microwave methods for development of the THz frequency range has resulted in elaboration of high precision THz spectrometers based on nonstationary effects. The spectrometers characteristics (spectral resolution and sensitivity) meet the requirements for high precision analysis. The gas analyzers, based on the high precision spectrometers, have been successfully applied for analytical investigations of gas impurities in high pure substances. These investigations can be carried out both in absorption cell and in reactor. The devices can be used for ecological monitoring, detecting the components of chemical weapons and explosive in the atmosphere. The great field of THz investigations is the medicine application. Using the THz spectrometers developed one can detect markers for some diseases in exhaled air.

Carbon Nanofiber-Based, High-Frequency, High-Q, Miniaturized Mechanical Resonators

NASA Technical Reports Server (NTRS)

Kaul, Anupama B.; Epp, Larry W.; Bagge, Leif

2011-01-01

High Q resonators are a critical component of stable, low-noise communication systems, radar, and precise timing applications such as atomic clocks. In electronic resonators based on Si integrated circuits, resistive losses increase as a result of the continued reduction in device dimensions, which decreases their Q values. On the other hand, due to the mechanical construct of bulk acoustic wave (BAW) and surface acoustic wave (SAW) resonators, such loss mechanisms are absent, enabling higher Q-values for both BAW and SAW resonators compared to their electronic counterparts. The other advantages of mechanical resonators are their inherently higher radiation tolerance, a factor that makes them attractive for NASA s extreme environment planetary missions, for example to the Jovian environments where the radiation doses are at hostile levels. Despite these advantages, both BAW and SAW resonators suffer from low resonant frequencies and they are also physically large, which precludes their integration into miniaturized electronic systems. Because there is a need to move the resonant frequency of oscillators to the order of gigahertz, new technologies and materials are being investigated that will make performance at those frequencies attainable. By moving to nanoscale structures, in this case vertically oriented, cantilevered carbon nanotubes (CNTs), that have larger aspect ratios (length/thickness) and extremely high elastic moduli, it is possible to overcome the two disadvantages of both bulk acoustic wave (BAW) and surface acoustic wave (SAW) resonators. Nano-electro-mechanical systems (NEMS) that utilize high aspect ratio nanomaterials exhibiting high elastic moduli (e.g., carbon-based nanomaterials) benefit from high Qs, operate at high frequency, and have small force constants that translate to high responsivity that results in improved sensitivity, lower power consumption, and im - proved tunablity. NEMS resonators have recently been demonstrated using topdown

High-Frequency Normal Mode Propagation in Aluminum Cylinders

USGS Publications Warehouse

Lee, Myung W.; Waite, William F.

2009-01-01

Acoustic measurements made using compressional-wave (P-wave) and shear-wave (S-wave) transducers in aluminum cylinders reveal waveform features with high amplitudes and with velocities that depend on the feature's dominant frequency. In a given waveform, high-frequency features generally arrive earlier than low-frequency features, typical for normal mode propagation. To analyze these waveforms, the elastic equation is solved in a cylindrical coordinate system for the high-frequency case in which the acoustic wavelength is small compared to the cylinder geometry, and the surrounding medium is air. Dispersive P- and S-wave normal mode propagations are predicted to exist, but owing to complex interference patterns inside a cylinder, the phase and group velocities are not smooth functions of frequency. To assess the normal mode group velocities and relative amplitudes, approximate dispersion relations are derived using Bessel functions. The utility of the normal mode theory and approximations from a theoretical and experimental standpoint are demonstrated by showing how the sequence of P- and S-wave normal mode arrivals can vary between samples of different size, and how fundamental normal modes can be mistaken for the faster, but significantly smaller amplitude, P- and S-body waves from which P- and S-wave speeds are calculated.

[Effect of high frequency electrotherapy on caspase-3 and ultra microstructure of hippocampus in rats following cerebral ischemia/reperfusion].

PubMed

Fan, Yongmei; Wang, Rumi; Zhang, Changjie; Peng, Wenna; Yin, Jing; Hu, Zhiping

2017-01-28

To investigate the effect of high frequency electrotherapy (HFE) on rat hippocampus after cerebral ischemia/reperfusion (I/R).
 Methods: A rat model of cerebral I/R injury was established. The rats were randomly divided into a sham group, an I/R group and an HFE group. The HFE group received thearapy daily for different sessions for 1, 3, 7 d. Neuronal deficit score,neuron ultra microstructure in the hippocampus and caspase-3 protein expression were measured on 1 st, 3 th and 7th d.
 Results: Compared with the I/R group, the HFE group showed the decreased neurological deficit scores, with significant differences between the 2 groups (P<0.05). The injury in HFE group was reduced compared with that in the I/R group based on the electron microscope test, with significant difference. Caspase-3 protein in brain tissue in the HFE group also downregulated compared with that in the I/R group (P<0.05).
 Conclusion: High frequency electrotherapy can improve neural function, suppress caspase-3 expression and apoptosis in nerve cells and improve the ultra microstructure of neurons, displaying a protective effect on cerebral I/R injury in rats.

High-frequency and hot-platen curing of medium-density fiberboards

Treesearch

R.R. Stevens; G.E. Woodson

1977-01-01

The effects of two curing methods- high-frequency heating and hot-platen heating- on the properties of a ure-formaldehyd-bonded medium-density fiberboard prepared with a southern-hardwoods furnish (50% southern red oak, 25% mockernut hickory, and 25% sweetgum) were studied. Boards of three densities- 38, 44, and 50 lb./ft.3- were cured by the two...

Neural coding of high-frequency tones

NASA Technical Reports Server (NTRS)

Howes, W. L.

1976-01-01

Available evidence was presented indicating that neural discharges in the auditory nerve display characteristic periodicities in response to any tonal stimulus including high-frequency stimuli, and that this periodicity corresponds to the subjective pitch.

Effective treatment of narcolepsy-like symptoms with high-frequency repetitive transcranial magnetic stimulation

PubMed Central

Lai, Jian-bo; Han, Mao-mao; Xu, Yi; Hu, Shao-hua

2017-01-01

Abstract Rationale: Narcolepsy is a rare sleep disorder with disrupted sleep-architecture. Clinical management of narcolepsy lies dominantly on symptom-driven pharmacotherapy. The treatment role of repetitive transcranial magnetic stimulation (rTMS) for narcolepsy remains unexplored. Patient concerns: In this paper, we present a case of a 14-year-old young girl with excessive daytime sleepiness (EDS), cataplexy and hypnagogic hallucinations. Diagnoses: After excluding other possible medical conditions, this patient was primarily diagnosed with narcolepsy. Interventions: The patient received 25 sessions of high-frequency rTMS over the left dorsolateral prefrontal cortex (DLPFC). Outcomes: The symptoms of EDS and cataplexy significantly improved after rTMS treatment. Meanwhile, her score in the Epworth sleep scale (ESS) also remarkably decreased. Lessons: This case indicates that rTMS may be selected as a safe and effective alternative strategy for treating narcolepsy-like symptoms. Well-designed researches are warranted in future investigations on this topic. PMID:29145290

High Frequency Ground Motion from Finite Fault Rupture Simulations

NASA Astrophysics Data System (ADS)

Crempien, Jorge G. F.

There are many tectonically active regions on earth with little or no recorded ground motions. The Eastern United States is a typical example of regions with active faults, but with low to medium seismicity that has prevented sufficient ground motion recordings. Because of this, it is necessary to use synthetic ground motion methods in order to estimate the earthquake hazard a region might have. Ground motion prediction equations for spectral acceleration typically have geometric attenuation proportional to the inverse of distance away from the fault. Earthquakes simulated with one-dimensional layered earth models have larger geometric attenuation than the observed ground motion recordings. We show that as incident angles of rays increase at welded boundaries between homogeneous flat layers, the transmitted rays decrease in amplitude dramatically. As the receiver distance increases away from the source, the angle of incidence of up-going rays increases, producing negligible transmitted ray amplitude, thus increasing the geometrical attenuation. To work around this problem we propose a model in which we separate wave propagation for low and high frequencies at a crossover frequency, typically 1Hz. The high-frequency portion of strong ground motion is computed with a homogeneous half-space and amplified with the available and more complex one- or three-dimensional crustal models using the quarter wavelength method. We also make use of seismic coda energy density observations as scattering impulse response functions. We incorporate scattering impulse response functions into our Green's functions by convolving the high-frequency homogeneous half-space Green's functions with normalized synthetic scatterograms to reproduce scattering physical effects in recorded seismograms. This method was validated against ground motion for earthquakes recorded in California and Japan, yielding results that capture the duration and spectral response of strong ground motion.

Frequency metrology using highly charged ions

NASA Astrophysics Data System (ADS)

Crespo López-Urrutia, J. R.

2016-06-01

Due to the scaling laws of relativistic fine structure splitting, many forbidden optical transitions appear within the ground state configurations of highly charged ions (HCI). In some hydrogen-like ions, even the hyperfine splitting of the 1s ground state gives rise to optical transitions. Given the very low polarizability of HCI, such laser-accessible transitions are extremely impervious to external perturbations and systematics that limit optical clock performance and arise from AC and DC Stark effects, such as black-body radiation and light shifts. Moreover, AC and DC Zeeman splitting are symmetric due to the much larger relativistic spin-orbit coupling and corresponding fine-structure splitting. Appropriate choice of states or magnetic sub-states with suitable total angular momentum and magnetic quantum numbers can lead to a cancellation of residual quadrupolar shifts. All these properties are very advantageous for the proposed use of HCI forbidden lines as optical frequency standards. Extremely magnified relativistic, quantum electrodynamic, and nuclear size contributions to the binding energies of the optically active electrons make HCI ideal tools for fundamental research, as in proposed studies of a possible time variation of the fine structure constant. Beyond this, HCI that cannot be photoionized by vacuum-ultraviolet photons could also provide frequency standards for future lasers operating in that range.

Real-time and high accuracy frequency measurements for intermediate frequency narrowband signals

NASA Astrophysics Data System (ADS)

Tian, Jing; Meng, Xiaofeng; Nie, Jing; Lin, Liwei

2018-01-01

Real-time and accurate measurements of intermediate frequency signals based on microprocessors are difficult due to the computational complexity and limited time constraints. In this paper, a fast and precise methodology based on the sigma-delta modulator is designed and implemented by first generating the twiddle factors using the designed recursive scheme. This scheme requires zero times of multiplications and only half amounts of addition operations by using the discrete Fourier transform (DFT) and the combination of the Rife algorithm and Fourier coefficient interpolation as compared with conventional methods such as DFT and Fast Fourier Transform. Experimentally, when the sampling frequency is 10 MHz, the real-time frequency measurements with intermediate frequency and narrowband signals have a measurement mean squared error of ±2.4 Hz. Furthermore, a single measurement of the whole system only requires approximately 0.3 s to achieve fast iteration, high precision, and less calculation time.

III-V HEMTs: low-noise devices for high-frequency applications

NASA Astrophysics Data System (ADS)

Mateos, Javier

2003-05-01

With the recent development of broadband and satellite communications, one of the main engines for the advance of modern Microelectronics is the fabrication of devices with increasing cutoff frequency and lowest possible level of noise. Even if heterojunction bipolar devices (HBTs) have reached a good frequency performance, the top end of high frequency low-noise applications is monopolized by unipolar devices, mainly HEMTs (High Electron Mobility Transistors). In particular, within the vast family of heterojunction devices, the best results ever reported in the W-band have been obtained with InP based HEMTs using the AlInAs/InGaAs material system, improving those of usual GaAs based pseudomorphic HEMTs. In field effect devices, the reduction of the gate length (Lg) up to the technological limit is the main way to achieve the maximum performances. But the design of the devices is not so simple, when reducing the gate length it is convenient to keep constant the aspect ratio (gate length over gate-to-channel distance) in order to limit short channel effects. This operation can lead to the appearance of other unwanted effects, like the depletion of the channel due to the surface potential or the tunneling of electrons from the channel to the gate. Therefore, in order to optimize the high frequency or the low-noise behavior of the devices (that usually can not be reached together) not only the gate-to-channel distance must be chosen carefully, but also many other technological parameters (both geometrical and electrical): composition of materials, width of the device, length, depth and position of the recess, thickness and doping of the different layers, etc. Historically, these parameters have been optimized by classical simulation techniques or, when such simulations are not physically applicable, by the expensive 'test and error' procedure. With the use of computer simulation, the design optimization can be made in a short time and with no money spent. However

Effect of centrifugal force on natural frequency of lateral vibration of rotating shafts

NASA Astrophysics Data System (ADS)

Behzad, M.; Bastami, A. R.

2004-07-01

This paper investigates the effect of shaft rotation on its natural frequency. Apart from gyroscopic effect, the axial force originated from centrifugal force and the Poisson effect results in change of shaft natural frequency. D'Alembert principle for shaft in cylindrical co-ordinate system, along with the stress-strain relation, gives the non-homogenous linear differential equation, which can be used to calculate axial stress in the shaft. Numerical results of this study show that axial stress produced by shaft rotation has a major effect on the natural frequency of long high-speed shafts, while shaft diameter has no influence on the results. In addition, change in lateral natural frequency due to gyroscopic effect is compared with the results of this study.

Beyond Phonotactic Frequency: Presentation Frequency Effects Word Productions in Specific Language Impairment

ERIC Educational Resources Information Center

Plante, Elena; Bahl, Megha; Vance, Rebecca; Gerken, LouAnn

2011-01-01

Phonotactic frequency effects on word production are thought to reflect accumulated experience with a language. Here we demonstrate that frequency effects can also be obtained through short-term manipulations of the input to children. We presented children with nonwords in an experiment that systematically manipulated English phonotactic frequency…

Electron Scattering by High-Frequency Whistler Waves at Earth's Bow Shock

NASA Technical Reports Server (NTRS)

Oka, M.; Wilson, L. B., III; Phan, T. D.; Hull, A. J.; Amano, T.; Hoshino, M.; Argall, M. R.; Le Contel, O.; Agapitov, O.; Gersham, D. J.;

High-frequency ultrasound-responsive block copolymer micelle.

PubMed

Wang, Jie; Pelletier, Maxime; Zhang, Hongji; Xia, Hesheng; Zhao, Yue

2009-11-17

Micelles of a diblock copolymer composed of poly(ethylene oxide) and poly(2-tetrahydropyranyl methacrylate) (PEO-b-PTHPMA) in aqueous solution could be disrupted by high-frequency ultrasound (1.1 MHz). It was found that, upon exposure to a high-intensity focused ultrasound (HIFU) beam at room temperature, the pH value of the micellar solution decreased over irradiation time. The infrared spectroscopic analysis of solid block copolymer samples collected from the ultrasound irradiated micellar solution revealed the formation of carboxylic acid dimers and hydroxyl groups. These characterization results suggest that the high-frequency HIFU beam could induce the hydrolysis reaction of THPMA at room temperature resulting in the cleavage of THP groups. The disruption of PEO-b-PTHPMA micelles by ultrasound was investigated by using dynamic light scattering, atomic force microscopy, and fluorescence spectroscopy. On the basis of the pH change, it was found that the disruption process was determined by a number of factors such as the ultrasound power, the micellar solution volume and the location of the focal spot of the ultrasound beam. This study shows the potential to develop ultrasound-sensitive block copolymer micelles by having labile chemical bonds in the polymer structure, and to use the high-frequency HIFU to trigger a chemical reaction for the disruption of micelles.

Impacts of amorphous and crystalline cobalt ferrite layers on the giant magneto-impedance response of a soft ferromagnetic amorphous ribbon

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mukherjee, D.; Devkota, J.; Ruiz, A.

2014-09-28

A systematic study of the effect of depositing CoFe₂O₄ (CFO) films of various thicknesses (d = 0–600 nm) on the giant magneto-impedance (GMI) response of a soft ferromagnetic amorphous ribbon Co₆₅Fe₄Ni₂Si₁₅B₁₄ has been performed. The CFO films were grown on the amorphous ribbons by the pulsed laser deposition technique. X-ray diffraction and transmission electron microscopy revealed a structural variation of the CFO film from amorphous to polycrystalline as the thickness of the CFO film exceeded a critical value of 300 nm. Atomic force microscopy evidenced the increase in surface roughness of the CFO film as the thickness of the CFOmore » film was increased. These changes in the crystallinity and morphology of the CFO film were found to have a distinct impact on the GMI response of the ribbon. Relative to the bare ribbon, coating of amorphous CFO films significantly enhanced the GMI response of the ribbon, while polycrystalline CFO films decreased it considerably. The maximum GMI response was achieved near the onset of the structural transition of the CFO film. These findings are of practical importance in developing high-sensitivity magnetic sensors.« less

Basis of Ionospheric Modification by High-Frequency Waves

DTIC Science & Technology

2007-06-01

for conducting ionospheric heating experiments in Gakona, Alaska, as part of the High Frequency Active Auroral Research Program ( HAARP ) [5], is being...upgraded. The upgraded HAARP HF transmitting system will be a phased-array antenna of 180 elements. Each element is a cross dipole, which radiates a...supported by the High Frequency Active Auroral Research Program ( HAARP ), the Air Force Research Laboratory at Hanscom Air Force Base, MA, and by the Office

High-resolution frequency measurement method with a wide-frequency range based on a quantized phase step law.

PubMed

Du, Baoqiang; Dong, Shaofeng; Wang, Yanfeng; Guo, Shuting; Cao, Lingzhi; Zhou, Wei; Zuo, Yandi; Liu, Dan

2013-11-01

A wide-frequency and high-resolution frequency measurement method based on the quantized phase step law is presented in this paper. Utilizing a variation law of the phase differences, the direct different frequency phase processing, and the phase group synchronization phenomenon, combining an A/D converter and the adaptive phase shifting principle, a counter gate is established in the phase coincidences at one-group intervals, which eliminates the ±1 counter error in the traditional frequency measurement method. More importantly, the direct phase comparison, the measurement, and the control between any periodic signals have been realized without frequency normalization in this method. Experimental results show that sub-picosecond resolution can be easily obtained in the frequency measurement, the frequency standard comparison, and the phase-locked control based on the phase quantization processing technique. The method may be widely used in navigation positioning, space techniques, communication, radar, astronomy, atomic frequency standards, and other high-tech fields.

High-frequency response and the possibilities of frequency-tunable narrow-band terahertz amplification in resonant tunneling nanostructures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kapaev, V. V., E-mail: kapaev@sci.lebedev.ru; Kopaev, Yu. V.; Savinov, S. A.

2013-03-15

The characteristics of the high-frequency response of single- and double-well resonant tunneling structures in a dc electric field are investigated on the basis of the numerical solution of a time-dependent Schroedinger equation with open boundary conditions. The frequency dependence of the real part of high frequency conductivity (high-frequency response) in In{sub 0.53}Ga{sub 0.47}As/AlAs/InP structures is analyzed in detail for various values of the dc voltage V{sub dc} in the negative differential resistance (NDR) region. It is shown that double-well three-barrier structures are promising for the design of terahertz-band oscillators. The presence of two resonant states with close energies in suchmore » structures leads to a resonant (in frequency) response whose frequency is determined by the energy difference between these levels and can be controlled by varying the parameters of the structure. It is shown that, in principle, such structures admit narrow-band amplification, tuning of the amplification frequency, and a fine control of the amplification (oscillation) frequency in a wide range of terahertz frequencies by varying a dc electric voltage applied to the structure. Starting from a certain width of the central intermediate barrier in double-well structures, one can observe a collapse of resonances, where the structure behaves like a single-well system. This phenomenon imposes a lower limit on the oscillation frequency in three-barrier resonant tunneling structures.« less

Optimum design on refrigeration system of high-repetition-frequency laser

NASA Astrophysics Data System (ADS)

Li, Gang; Li, Li; Jin, Yezhou; Sun, Xinhua; Mao, Shaojuan; Wang, Yuanbo

2014-12-01

A refrigeration system with fluid cycle, semiconductor cooler and air cooler is designed to solve the problems of thermal lensing effect and unstable output of high-repetition-frequency solid-state lasers. Utilizing a circulating water pump, water recycling system carries the water into laser cavity to absorb the heat then get to water cooling head. The water cooling head compacts cold spot of semiconductor cooling chips, so the heat is carried to hot spot which contacts the radiating fins, then is expelled through cooling fan. Finally, the cooled water return to tank. The above processes circulate to achieve the purposes of highly effective refrigeration in miniative solid-state lasers.The refrigeration and temperature control components are designed strictly to ensure refrigeration effect and practicability. we also set up a experiment to test the performances of this refrigeration system, the results show that the relationship between water temperature and cooling power of semiconductor cooling chip is linear at 20°C-30°C (operating temperature range of Nd:YAG), the higher of the water temperature, the higher of cooling power. According to the results, cooling power of single semiconductor cooling chip is above 60W, and the total cooling power of three semiconductor cooling chips achieves 200W that will satisfy the refrigeration require of the miniative solid-state lasers.The performance parameters of laser pulse are also tested, include pulse waveform, spectrogram and laser spot. All of that indicate that this refrigeration system can ensure the output of high-repetition-frequency pulse whit high power and stability.

Level of Automation and Failure Frequency Effects on Simulated Lunar Lander Performance

NASA Technical Reports Server (NTRS)

Marquez, Jessica J.; Ramirez, Margarita

2014-01-01

A human-in-the-loop experiment was conducted at the NASA Ames Research Center Vertical Motion Simulator, where instrument-rated pilots completed a simulated terminal descent phase of a lunar landing. Ten pilots participated in a 2 x 2 mixed design experiment, with level of automation as the within-subjects factor and failure frequency as the between subjects factor. The two evaluated levels of automation were high (fully automated landing) and low (manual controlled landing). During test trials, participants were exposed to either a high number of failures (75% failure frequency) or low number of failures (25% failure frequency). In order to investigate the pilots' sensitivity to changes in levels of automation and failure frequency, the dependent measure selected for this experiment was accuracy of failure diagnosis, from which D Prime and Decision Criterion were derived. For each of the dependent measures, no significant difference was found for level of automation and no significant interaction was detected between level of automation and failure frequency. A significant effect was identified for failure frequency suggesting failure frequency has a significant effect on pilots' sensitivity to failure detection and diagnosis. Participants were more likely to correctly identify and diagnose failures if they experienced the higher levels of failures, regardless of level of automation

Long range ultra-high frequency (UHF) radio frequency identification (RFID) antenna design

NASA Astrophysics Data System (ADS)

Reynolds, Nathan D.

There is an ever-increasing demand for radio frequency identification (RFID) tags that are passive, long range, and mountable on multiple surfaces. Currently, RFID technology is utilized in numerous applications such as supply chain management, access control, and public transportation. With the combination of sensory systems in recent years, the applications of RFID technology have been extended beyond tracking and identifying. This extension includes applications such as environmental monitoring and healthcare applications. The available sensory systems usually operate in the medium or high frequency bands and have a low read range. However, the range limitations of these systems are being overcome by the development of RFID sensors focused on utilizing tags in the ultra-high frequency (UHF) band. Generally, RFID tags have to be mounted to the object that is being identified. Often the objects requiring identification are metallic. The inherent properties of metallic objects have substantial effects on nearby electromagnetic radiation; therefore, the operation of the tag antenna is affected when mounted on a metallic surface. This outlines one of the most challenging problems for RFID systems today: the optimization of tag antenna performance in a complex environment. In this research, a novel UHF RFID tag antenna, which has a low profile, long range, and is mountable on metallic surfaces, is designed analytically and simulated using a 3-D electromagnetic simulator, ANSYS HFSS. A microstrip patch antenna is selected as the antenna structure, as patch antennas are low profile and suitable for mounting on metallic surfaces. Matching and theoretical models of the microstrip patch antenna are investigated. Once matching and theory of a microstrip patch antenna is thoroughly understood, a unique design technique using electromagnetic band gap (EBG) structures is explored. This research shows that the utilization of an EBG structure in the patch antenna design yields

An improved fast acquisition phase frequency detector for high speed phase-locked loops

NASA Astrophysics Data System (ADS)

Zhang, Lei; Wang, Zongmin; Zhang, Tieliang; Peng, Xinmang

2018-04-01

Phase-locked loops (PLL) have been widely applied in many high-speed designs, such as microprocessors or communication systems. In this paper, an improved fast acquisition phase frequency detector for high speed phase-locked loops is proposed. An improved structure based on dynamic latch is used to eliminate the non-ideal effect such as dead zone and blind zone. And frequency dividers are utilized to vastly extend the phase difference detection range and enhance the operation frequency of the PLL. Proposed PFD has been implemented in 65nm CMOS technology, which occupies an area of 0.0016mm2 and consumes 1.5mW only. Simulation results demonstrate that maximum operation frequency can be up to 5GHz. In addition, the acquisition time of PLL using proposed PFD is 1.0us which is 2.6 times faster than that of the PLL using latch-based PFD without divider.

Model Equation for Acoustic Nonlinear Measurement of Dispersive Specimens at High Frequency