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1

Capture of metallic copper by high gradient magnetic separation system.  

PubMed

Valence copper was recovered from wastewater by chemical reduction and use of a high gradient magnetic separation (HGMS) system. Ammonia (NH3) and sodium dithionate (Na2S2O4) at a molar ratio of [Cu]:[NH3]:[Na2S2O4] = 1:4:3 at pH = 9.5 were used first to chemically reduce copper ion to metallic copper; the resultant metal solids were captured in an upflowing reactor space equipped with a permalloy matrix net under a high gradient magnetic field. The captured solids were predominantly 6-20 microm in diameter, with Cu2O and CuO present among the solids. Four treatment configurations with and without the use of magnetic field and metal alloy as the matrix net were tested and their effects evaluated: (1) no magnetic field or matrix, (2) no magnetic field but with matrix, (3) with magnetic field but no matrix, (4) with both magnetic field and matrix. At flow rates of 40, 60, 80 and 100 cm3/min, capture efficiencies for metallic copper in the absence of magnetic field were 87%, 86%, 63%, and 39%, respectively, and in the presence of magnetic field were 99%, 98%, 95%, and 93%, respectively. The HGMS was critical for a high capture efficiency, whereas a matrix net only marginally enhanced it. Additional tests with a larger reactor confirmed similarly high efficiencies of > 85%. The use of an alloy matrix appeared to be important when high flow rates are most likely to be employed in practical applications. PMID:22329132

Wu, Wan-I; Wu, Chung-Hsin; Hong, P K Andy; Lin, Cheng-Fang

2011-10-01

2

Use of high gradient magnetic separation for actinide application  

SciTech Connect

Decontamination of materials such as soils or waste water that contain radioactive isotopes, heavy metals, or hazardous components is a subject of great interest. Magnetic separation is a physical separation process that segregates materials on the basis of magnetic susceptibility. Because the process relies on physical properties, separations can be achieved while producing a minimum of secondary waste. Most traditional physical separation processes effectively treat particles larger than 70 microns. In many situations, the radioactive contaminants are found concentrated in the fine particle size fraction of less than 20 microns. For effective decontamination of the fine particle size fraction most current operations resort to chemical dissolution methods for treatment. High gradient magnetic separation (HGMS) is able to effectively treat particles from 90 to {approximately}0.1 micron in diameter. The technology is currently used on the 60 ton per hour scale in the kaolin clay industry. When the field gradient is of sufficiently high intensity, paramagnetic particles can be physically captured and separated from extraneous nonmagnetic material. Because all actinide compounds are paramagnetic, magnetic separation of actinide containing mixtures is feasible. The advent of reliable superconducting magnets also makes magnetic separation of weakly paramagnetic species attractive. HGMS work at Los Alamos National Laboratory (LANL) is being developed for soil remediation, waste water treatment and treatment of actinide chemical processing residues. LANL and Lockheed Environmental Systems and Technologies Company (LESAT) have worked on a co-operative research and development agreement (CRADA) to develop HGMS for radioactive soil decontamination. The program is designed to transfer HGMS from the laboratory and other industries for the commercial treatment of radioactive contaminated materials. 9 refs., 2 figs., 2 tabs.

Avens, L.R.; Worl, L.A.; Padilla, D.D.

1996-08-01

3

Medical protein separation system using high gradient magnetic separation by superconducting magnet  

NASA Astrophysics Data System (ADS)

A high gradient magnetic separation system for medical protein using affinity magnetic nano-beads has been developed. Medical protein such as monoclonal antibody or immunoglobulin is an important substance as a medicine for cancer etc. However; the separation system of these medical protein has very low separation rate and the cost of product is extremely high. The developed system shows very high separation efficiency and can achieve low cost by large production rate compared to the system now using in this field. The system consists of a 3T superconducting magnet cooled by a cryo-cooler, a filter made of fine magnetic metal wires of about 30?m diameter and a demagnetization circuit and a liquid circulation pump for solvent containing medical protein. Affinity magnetic nano-beads is covered with the medical protein after agitation of solvent containing the protein and nano-beads, then the solvent flows through the system and the beads are trapped in the filters by high gradient magnetic field. The beads are released and flow out of the system by the AC demagnetization of the filters using LC resonance circuits after discharge of the magnet. The test results shows 97.8% of the magnetic nano-beads in pure water were captured and 94.1% of total beads were collected.

Kamioka, Y.; Agatsuma, K.; Kajikawa, K.; Ueda, H.; Furuse, M.; Fuchino, S.; Iitsuka, T.; Nakamura, S.

2014-01-01

4

Application of high temperature superconductors to high-gradient magnetic separation  

Microsoft Academic Search

High Gradient Magnetic Separation (HGMS) is a powerful technique which can be used to separate widely dispersed contaminants from a host material, This technology can separate magnetic solids from other solids, liquids, or gases. As the name implies, HGMS uses large magnetic field gradients to separate ferromagnetic and paramagnetic particles. HGMS separators usually consist of a high-field solenoid magnet, the

M. A. Daugherty; F. C. Prenger; D. D. Hill; D. E. Daney; L. W. Worl; A. R. Schake; D. D. Padilla

1994-01-01

5

Microfluidic high gradient magnetic cell separation David W. Inglisa  

E-print Network

and by the selective attachment of magnetic beads has recently been demonstrated on microfluidic devices. We discuss microfluidic devices for the magnetic separation of blood cells. We also discuss our attempts to integrate. © 2006 American Institute of Physics. DOI: 10.1063/1.2165782 INTRODUCTION Cell separation by centrifuge

6

Filter Capacity Predictions for the Capture of Magnetic Microparticles by High-Gradient Magnetic Separation  

Microsoft Academic Search

We present experimental and theoretical methods to predict maximum and working filter capacities for the capture of superparamagnetic microparticles through high-gradient magnetic separation (HGMS). For this, we employed various combinations of nine different HGMS filter matrices and two types of superparamagnetic microparticles. By calculating the separated particle mass per filter mesh area, we clearly demonstrated the influences of wire diameter

Niklas A. Ebner; Cláudia S. G. Gomes; Timothy J. Hobley; Owen R. T. Thomas; Matthias Franzreb

2007-01-01

7

Modeling high gradient magnetic separation from biological fluids.  

SciTech Connect

A proposed portable magnetic separator consists of an array of biocompatible capillary tubing and magnetizable wires immersed in an externally applied homogeneous magnetic field. While subject to the homogeneous magnetic field, the wires create high magnetic field gradients, which aid in the collection of blood-borne magnetic nanospheres from blood flow. In this study, a 3-D numerical model was created using COMSOL Multiphysics 3.2 software to determine the configuration of the wire-tubing array from two possible configurations, one being an array with rows alternating between wires and tubing, and the other being an array where wire and tubing alternate in two directions. The results demonstrated that the second configuration would actually capture more of the magnetic spheres. Experimental data obtained by our group support this numerical result.

Bockenfeld, D.; Chen, H.; Rempfer, D.; Kaminski, M. D.; Rosengart, A. J.; Chemical Engineering; Illinois Inst. of Tech.; Univ. of Chicago, Pritzker School of Medicine

2006-01-01

8

High gradient magnetic separation of iron oxide minerals from soil clays  

E-print Network

HIGH GRADIENT MAGNETIC SEPARATION OF IRON OXIDE MINERALS FROM SOIL CLAYS A Thesis by DARRELL GENE SCHULZE Submitted to the Graduate College of Texas AIM University in partial fulfillment of the requirement for the degree of MASTER OF SCIENCE... December 1977 Major Subject: Soil Science HIGH GRADIENT MAGNETIC SEPARATION OF IRON OXIDE MINERALS FROM SOIL CLAYS A Thesis DARRELL GENE SCHULZE Approved as to style and content by: (Chairman of C ittee) epartm t) j (Member) (Membe December 1977...

Schulze, Darrell Gene

2012-06-07

9

Use of High-Gradient Magnetic Fields for the Separation of Macromolecules  

Microsoft Academic Search

High gradient magnetic field separation (HGMS) has been used to separate several types of > 1 ?m sized ferro- or paramagnetic particles from bulk streams. The majority of the studies have been carried out using a single ferromagnetic wire or wire mesh to produce the field gradients necessary for particle capture. The purpose of this paper is to examine the

T. C. Scott; T. L. Brumfield

1988-01-01

10

A novel high-gradient magnetic separator (HGMS) design for biotech applications  

Microsoft Academic Search

A novel high-gradient magnetic separator (HGMS) has been designed to meet the strong requirements of biotech processes to grant high product yield, efficient cleanability and low operating costs. The novel design using a rotary permanent magnet leads to an \\

C. Hoffmann; M. Franzreb; W. H. Holl

2002-01-01

11

APPLICATION OF HIGH-GRADIENT MAGNETIC SEPARATION TO FINE PARTICLE CONTROL  

EPA Science Inventory

The report gives results of an assessment of the potential use of high-gradient magnetic separation (HGMS) as a means of collecting gas stream particulates. The assessment included both experiments and analyses of theoretical models. Phase I included evaluations of theoretical ex...

12

High gradient magnetic separation versus expanded bed adsorption: a first principle comparison.  

PubMed

A robust new adsorptive separation technique specifically designed for direct product capture from crude bioprocess feedstreams is introduced and compared with the current bench mark technique, expanded bed adsorption. The method employs product adsorption onto sub-micron sized non-porous superparamagnetic supports followed by rapid separation of the 'loaded' adsorbents from the feedstock using high gradient magnetic separation technology. For the recovery of Savinase from a cell-free Bacillus clausii fermentation liquor using bacitracin-linked adsorbents, the integrated magnetic separation system exhibited substantially enhanced productivity over expanded bed adsorption when operated at processing velocities greater than 48 m h(-1). Use of the bacitracin-linked magnetic supports for a single cycle of batch adsorption and subsequent capture by high gradient magnetic separation at a processing rate of 12 m h(-1) resulted in a 2.2-fold higher productivity relative to expanded bed adsorption, while an increase in adsorbent collection rate to 72 m h(-1) raised the productivity to 10.7 times that of expanded bed adsorption. When the number of batch adsorption cycles was then increased to three, significant drops in both magnetic adsorbent consumption (3.6 fold) and filter volume required (1.3 fold) could be achieved at the expense of a reduction in productivity from 10.7 to 4.4 times that of expanded bed adsorption. PMID:11787803

Hubbuch, J J; Matthiesen, D B; Hobley, T J; Thomas, O R

2001-01-01

13

Application of high temperature superconductors to high-gradient magnetic separation  

SciTech Connect

High Gradient Magnetic Separation (HGMS) is a powerful technique which can be used to separate widely dispersed contaminants from a host material, This technology can separate magnetic solids from other solids, liquids or gases. As the name implies HGMS uses large magnetic field gradients to separate ferromagnetic and paramagnetic particles. HGMS separators usually consist of a high-field solenoid magnet, the bore of which contains a fine-structured, ferromagnetic matrix material. The matrix material locally distorts the magnetic field and creates large field gradients in the vicinity of the matrix elements. These elements then become trapping sites for magnetic particles and are the basis for the magnetic separation. In this paper we discuss the design and construction of a prototype HGMS unit using a magnet made with high temperature superconductors (HTS). The prototype consists of an outer vacuum vessel which contains the HTS solenoid magnet The magnet is surrounded by a thermal radiation shield and multilayer insulation (MLI) blankets. The magnet, thermal shield and current leads all operate in a vacuum and are cooled by a cryocooler. High temperature superconducting current leads are used to reduce the heat leak from the ambient environment to the HTS magnet.

Daugherty, M.A.; Prenger, F.C.; Hill, D.D.; Daney, D.E.; Worl, L.W.; Schake, A.R.; Padilla, D.D.

1994-06-01

14

Application of high temperature superconductors to high-gradient magnetic separation  

NASA Astrophysics Data System (ADS)

High Gradient Magnetic Separation (HGMS) is a powerful technique which can be used to separate widely dispersed contaminants from a host material, This technology can separate magnetic solids from other solids, liquids, or gases. As the name implies, HGMS uses large magnetic field gradients to separate ferromagnetic and paramagnetic particles. HGMS separators usually consist of a high-field solenoid magnet, the bore which contains a fine-structured, ferromagnetic matrix material. The matrix material locally distorts the magnetic field and creates large field gradients in the vicinity of the matrix elements. These elements then become trapping sites for magnetic particles and are the basis for the magnetic separation. In this paper, we discuss the design and construction of a prototype HGMS unit using a magnet made with high temperature superconductors (HTS). The prototype consists of an outer vacuum vessel which contains the HTS solenoid magnet. The magnet is surrounded by a thermal radiation shield and multilayer insulation (MLI) blankets. The magnet, thermal shield, and current leads all operate in a vacuum and are cooled by a cryocooler. High temperature superconducting current leads are used to reduce the heat leak from the ambient environment to the HTS magnet.

Daugherty, M. A.; Prenger, F. C.; Hill, D. D.; Daney, D. E.; Worl, L. W.; Schake, A. R.; Padilla, D. D.

15

Cr-polluted soil studied by high gradient magnetic separation and electron probe  

SciTech Connect

An Fe-rich soil from the site of a former leather tannery, heavily polluted with Cr, was studied using a combination of wet chemical analysis, high gradient magnetic separation (HGMS), and electron probe microanalysis (EPMA). It is demonstrated that such a combination is a powerful tool for the characterization of polluted soils, especially in cases where the pollution is present as discrete particles. Both EPMA and magnetic separation data indicated that the Cr pollution was present as a hydrous Cr-oxide phase. The Cr does not correlate with the Fe minerals, most likely as a result of the initial high Cr concentrations in the soil, which lead to precipitation of separate hydrous Cr-oxide minerals and Fe minerals. The Cr-containing material is present as (layered) aggregates, which are formed around larger quartz grains or around very small other particles that served as precipitation nuclei. Magnetic separation tests show that the Cr pollution can largely be removed by HGMS.

Rikers, R.A.; Voncken, J.H.L.; Dalmijn, W.L. [Delft Univ. of Technology (Netherlands)

1998-12-01

16

Setting up High Gradient Magnetic Separation for combating eutrophication of inland waters.  

PubMed

To find new approaches to devise technologies for handling with eutrophication of inland waters is a global challenge. Separation of the P from water under conditions of continuous flow is proposed as an alternative and effective method. This work is based on using highly magnetic particles as the seeding adsorbent material and their later removal from solution by High Gradient Magnetic Separation (HGMS). Contrast to other methods based on batch conditions, large volumes of water can be easily handled by HGMS because of decreasing retention times. This study identifies the best working conditions for removing P from solution by investigating the effects of a set of four different experimental variables: sonication time, flow rate (as it determines the retention time of particles in the magnetic field), magnetic field strength and the iron (Fe) particles/P concentration ratio. Additionally, the change of P removal efficiency with time (build up effect) and the possibility of reusing magnetic particles were also studied. Our results evidenced that while flow rate does not significantly affect P removal efficiency in the range 0.08-0.36 mL s(-1), sonication time, magnetic field strength and the Fe particles/P concentration ratio are the main factors controlling magnetic separation process. PMID:21255924

Merino-Martos, A; de Vicente, J; Cruz-Pizarro, L; de Vicente, I

2011-02-28

17

TREATMENT OF COMBINED SEWER OVERFLOWS BY HIGH GRADIENT MAGNETIC SEPARATION. ON-SITE TESTING WITH MOBILE PILOT PLANT TRAILER  

EPA Science Inventory

Seeded water treatment using a SALA high gradient magnetic separator pilot plant system was conducted on combined sewer overflows and raw sewage at SALA Magnetics in Cambridge, MA and at on-site locations in the Boston area. Special emphasis was placed on specific design and oper...

18

Chemical interferences when using high gradient magnetic separation for phosphate removal: consequences for lake restoration.  

PubMed

A promising method for lake restoration is the treatment of lake inlets through the specific adsorption of phosphate (P) on strongly magnetizable particles (Fe) and their subsequent removal using in-flow high gradient magnetic separation (HGMS) techniques. In this work, we report an extensive investigation on the chemical interferences affecting P removal efficiencies in natural waters from 20 Mediterranean ponds and reservoirs. A set of three treatments were considered based on different Fe particles/P concentration ratios. High P removal efficiencies (>80%) were found in freshwater lakes (conductivities<600 ? S cm(-1)). However, a significant reduction in P removal was observed for extremely high mineralized waters. Correlation analysis showed that major cations (Mg(2+), Na(+) and K(+)) and anions (SO(4)(2-) and Cl(-)) played an essential role in P removal efficiency. Comparison between different treatments have shown that when increasing P and Fe concentrations at the same rate or when increasing Fe concentrations for a fixed P concentration, there exist systematic reductions in the slope of the regression lines relating P removal efficiency and the concentration of different chemical variables. These results evidence a general reduction in the chemical competition between P and other ions for adsorption sites on Fe particles. Additional analyses also revealed a reduction in water color, dissolved organic carbon (DOC) and reactive silicate (Si) concentrations with the addition of Fe microparticles. PMID:21741173

de Vicente, I; Merino-Martos, A; Guerrero, F; Amores, V; de Vicente, J

2011-09-15

19

CAPTURE AND RETRIEVAL OF PLUTONIUM OXIDE PARTICLES AT ULTRA-LOW CONCENTRATIONS USING HIGH-GRADIENT MAGNETIC SEPARATION  

Microsoft Academic Search

A high-gradient magnetic separation system has been developed for capture and retrieval of ultra-low plutonium oxide concentrations. The application of advanced matrix materials and improved methodology has demonstrated the effective collection and recovery of submicron paramagnetic actinide particles with particle concentrations as low as 10 M. Incorporation of multiple passes during recovery of magnetically captured particles improves the system mass balance.

Robert M. Wingo; David J. Devlin; Dallas D. Hill; Dennis D. Padilla; F. Coyne Prenger; Laura A. Worl

2002-01-01

20

2D modeling and preliminary in vitro investigation of a prototype high gradient magnetic separator for biomedical applications.  

PubMed

High gradient magnetic separation (HGMS) of magnetic materials from fluids or waste products has many established industrial applications. However, there is currently no technology employing HGMS for ex-vivo biomedical applications, such as for the removal of magnetic drug- or toxin-loaded spheres from the human blood stream. Importantly, human HGMS applications require special design modifications as, in contrast to conventional use where magnetic elements are permanently imbedded within the separation chambers, medical separators need to avoid direct contact between the magnetic materials and blood to reduce the risk of blood clotting and to facilitate convenient and safe treatment access for many individuals. We describe and investigate the performance of a magnetic separator prototype designed for biomedical applications. First, the capture efficiency of a prototype HGMS separator unit consisting of a short tubing segment and two opposing magnetizable fine wires along the outside of the tubing was investigated using 2D mathematical modeling. Second, the first-pass effectiveness to remove commercially available, magnetic polystyrene spheres from human blood using a single separator unit was experimentally verified. The theoretical and experimental data correlated well at low flow velocities (<5.0 cm/s) and high external magnetic fields (>0.05 T). This prototype separator unit removed >90% in a single pass of the magnetic spheres from water at mean flow velocity < or =8.0 cm/s and from blood mimic fluids (ethylene glycol-water solutions) at mean flow velocity < or =2.0 cm/s. In summary, we describe and prove the feasibility of a HGMS separator for biomedical applications. PMID:17400018

Chen, Haitao; Kaminski, Michael D; Rosengart, Axel J

2008-01-01

21

Paramagnetic microchip for high-gradient separation of blood cell  

Microsoft Academic Search

This paper presents a magnetophoretic separation method on a chip of white blood cells from blood under continuous flow. The separation of red blood cells from the whole blood is performed using a high gradient magnetic separation method under continuous flow to trap the particles inside the device. The device is fabricated by microfabrication technology and enables to capture the

Ciprian Iliescu; Guolin Xu; Elena Barbarini; Marioara Avram; Florina S. Iliescu

2008-01-01

22

Paramagnetic microchip for high-gradient separation of blood cell  

NASA Astrophysics Data System (ADS)

This paper presents a magnetophoretic separation method on a chip of white blood cells from blood under continuous flow. The separation of red blood cells from the whole blood is performed using a high gradient magnetic separation method under continuous flow to trap the particles inside the device. The device is fabricated by microfabrication technology and enables to capture the red blood cells without the use of labelling tecniques such as magnetic beads. The method consists of flowing diluted whole blood through a microfluidic channel where a ferromagnetic layer, subjected to a permanent magnetic field, is located. The majority of red blood cells are trapped at the bottom of the device while the rest of the blood is collected at the outlet. Experimental results show that an average of 95% of red blood cells are trapped in the device.

Iliescu, Ciprian; Xu, Guolin; Barbarini, Elena; Avram, Marioara; Iliescu, Florina S.

2008-12-01

23

High gradient magnetic beneficiation of dry pulverized coal via upwardly directed recirculating fluidization  

DOEpatents

This invention relates to an improved device and method for the high gradient magnetic beneficiation of dry pulverized coal, for the purpose of removing sulfur and ash from the coal whereby the product is a dry environmentally acceptable, low-sulfur fuel. The process involves upwardly directed recirculating air fluidization of selectively sized powdered coal in a separator having sections of increasing diameters in the direction of air flow, with magnetic field and flow rates chosen for optimum separations depending upon particulate size.

Eissenberg, David M. (Oak Ridge, TN); Liu, Yin-An (Opelika, AL)

1980-01-01

24

Ion imaging in a high-gradient magnetic guide  

NASA Astrophysics Data System (ADS)

We study a photoionization method to detect and image a narrow beam of cold atoms traveling along a high-gradient two-wire magnetic guide that is continuously on. Ions are accelerated in a compact acceleration region, directed through a drift region several centimeters in length, and detected using a position-sensitive ion detector. The potentials of several electrodes can be varied to adjust the imaging properties. Using ion trajectory simulations as well as experiments, we study the passage of the ions through the detection system, the magnification of the detection system, and the time-of-flight characteristics.

Vaidya, V. D.; Traxler, M.; Hempel, C.; Mhaskar, R. R.; Raithel, G.

2010-04-01

25

Ion imaging in a high-gradient magnetic guide.  

PubMed

We study a photoionization method to detect and image a narrow beam of cold atoms traveling along a high-gradient two-wire magnetic guide that is continuously on. Ions are accelerated in a compact acceleration region, directed through a drift region several centimeters in length, and detected using a position-sensitive ion detector. The potentials of several electrodes can be varied to adjust the imaging properties. Using ion trajectory simulations as well as experiments, we study the passage of the ions through the detection system, the magnification of the detection system, and the time-of-flight characteristics. PMID:20441327

Vaidya, V D; Traxler, M; Hempel, C; Mhaskar, R R; Raithel, G

2010-04-01

26

Ion imaging in a high-gradient magnetic guide  

SciTech Connect

We study a photoionization method to detect and image a narrow beam of cold atoms traveling along a high-gradient two-wire magnetic guide that is continuously on. Ions are accelerated in a compact acceleration region, directed through a drift region several centimeters in length, and detected using a position-sensitive ion detector. The potentials of several electrodes can be varied to adjust the imaging properties. Using ion trajectory simulations as well as experiments, we study the passage of the ions through the detection system, the magnification of the detection system, and the time-of-flight characteristics.

Vaidya, V. D. [JQI, University of Maryland, College Park, Maryland 20742 (United States); Traxler, M.; Mhaskar, R. R.; Raithel, G. [Department of Physics, University of Michigan, Ann Arbor, Michigan 48109 (United States); Hempel, C. [Institute for Quantum Optics and Quantum Information, Innsbruck A-6020 (Austria)

2010-04-15

27

Magnet driver for producing ultra-high gradient magnetic fields for magnetic resonance imaging  

Microsoft Academic Search

Pulsed gradient magnetic fields are required for magnetic resonance imaging (MRI). Many imaging sequences (e.g., echo planar imaging, diffusion tensor imaging) could be improved with shorter gradient pulses. MRI systems currently available typically require ramp times of hundreds of microseconds. The goal of the work described here is to achieve very high gradient fields, with very short rise times to

Howard D. Sanders; Steven C. Glidden; Daniel M. Warnow; Irving N. Weinberg; Pavel Stepanov; Roland Probst; Alan McMillan; Rao Gullapalli; Piotr M. Starewicz; William F. B. Punchard; Kai-Ming Lo; Stanley Thomas Fricke

2011-01-01

28

COLLECTION OF AIRBORNE PARTICLES BY A HIGH-GRADIENT PERMANENT MAGNETIC METHOD  

SciTech Connect

We report on the use of magnetic force in collection of airborne particles by a high- gradient permanent magnetic separation (HGPMS) device. Three aerosol particles of different magnetic susceptibility (NaCl, CuO, and Fe2O3) were generated in the electrical mobility size range of 10 to 200 nm and were used to study HGPMS collection. One HGPMS matrix element, made of stainless steel wool, was used in the device configuration. Three flow rates were selected to simulate the environmental wind speeds of interest to the study. Magnetic force was found to exhibit an insignificant effect on the separation of NaCl particles, even in the HGPMS configuration. Diffusion was a major mechanism in the removal of the diamagnetic particles; however, diffusion is insignificant under the influence of a high-gradient magnetic field for paramagnetic or ferromagnetic particles. The HGPMS showed high-performance collection (> 99%) of paramagnetic CuO and ferromagnetic Fe2O3 particles for particle sizes greater than or equal to 60 nm. As the wind speed increases, the influence of the magnetic force weakens, and the capability to remove particles from the gas stream diminishes. The results suggest that the HGPMS principle could be explored for development of an advanced miniaturized passive aerosol collector.

Cheng, Mengdawn [ORNL; Allman, Steve L [ORNL; Ludtka, Gerard Michael [ORNL; Avens, Larry R [ORNL

2014-01-01

29

High-Gradient Nanomagnets on Cantilevers for Sensitive Detection of Nuclear Magnetic Resonance  

PubMed Central

Detection of magnetic resonance as a force between a magnetic tip and nuclear spins has previously been shown to enable sub-10 nm resolution 1H imaging. Maximizing the spin force in such a magnetic resonance force microscopy (MRFM) experiment demands a high field gradient. In order to study a wide range of samples, it is equally desirable to locate the magnetic tip on the force sensor. Here we report the development of attonewton-sensitivity cantilevers with high gradient cobalt nanomagnet tips. The damage layer thickness and saturation magnetization of the magnetic material were characterized by X-ray photoelectron spectroscopy and superconducting quantum interference device magnetometry. The coercive field and saturation magnetization of an individual tip were quantified in situ using frequency-shift cantilever magnetometry. Measurements of cantilever dissipation versus magnetic field and tip-sample separation were conducted. MRFM signals from protons in a polystyrene film were studied versus rf irradiation frequency and tip-sample separation, and from this data the tip field and tip-field gradient were evaluated. Magnetic tip performance was assessed by numerically modeling the frequency dependence of the magnetic resonance signal. We observed a tip-field gradient ?Bztip??z estimated to be between 4.4 and 5.4 MT m?1, which is comparable to the gradient used in recent 4 nm resolution 1H imaging experiments and larger by nearly an order of magnitude than the gradient achieved in prior magnet-on-cantilever MRFM experiments. PMID:23033869

Longenecker, Jonilyn G.; Mamin, H. J.; Senko, Alexander W.; Chen, Lei; Rettner, Charles T.; Rugar, Daniel; Marohn, John A.

2012-01-01

30

High-gradient nanomagnets on cantilevers for sensitive detection of nuclear magnetic resonance.  

PubMed

Detection of magnetic resonance as a force between a magnetic tip and nuclear spins has previously been shown to enable sub-10 nm resolution 1H imaging. Maximizing the spin force in such a magnetic resonance force microscopy (MRFM) experiment demands a high field gradient. In order to study a wide range of samples, it is equally desirable to locate the magnetic tip on the force sensor. Here we report the development of attonewton-sensitivity cantilevers with high-gradient cobalt nanomagnet tips. The damage layer thickness and saturation magnetization of the magnetic material were characterized by X-ray photoelectron spectroscopy and superconducting quantum interference device magnetometry. The coercive field and saturation magnetization of an individual tip were quantified in situ using frequency-shift cantilever magnetometry. Measurements of cantilever dissipation versus magnetic field and tip–sample separation were conducted. MRFM signals from protons in a polystyrene film were studied versus rf irradiation frequency and tip–sample separation, and from this data the tip field and tip-field gradient were evaluated. Magnetic tip performance was assessed by numerically modeling the frequency dependence of the magnetic resonance signal. We observed a tip-field gradient ?B(z)(tip)/?z estimated to be between 4.4 and 5.4 MT m(–1), which is comparable to the gradient used in recent 4 nm resolution 1H imaging experiments and larger by nearly an order of magnitude than the gradient achieved in prior magnet-on-cantilever MRFM experiments. PMID:23033869

Longenecker, Jonilyn G; Mamin, H J; Senko, Alexander W; Chen, Lei; Rettner, Charles T; Rugar, Daniel; Marohn, John A

2012-11-27

31

High and ulta-high gradient quadrupole magnets  

SciTech Connect

Small bore conventional dc quadrupoles with apertures from 1 to 2.578cm were designed and prototypes built and measured. New fabrication techniques including the use of wire electric discharge milling (EDM) to economically generate the pole tip contours and aperture tolerances are described. Magnetic measurement data from a prototype of a 1cm aperture quadrupole with possible use in future e/sup +//e/sup -/ super colliders are presented. At a current of 400A, the lens achieved a gradient of 2.475 T/cm, and had an efficiency of 76.6%.

Brunk, W.O.; Walz, D.R.

1985-05-01

32

Magnetic separation for soil decontamination  

SciTech Connect

High gradient magnetic separation (HGMS) is a physical separation process that is used to extract magnetic particles from mixtures. The technology is used on a large scale in the kaolin clay industry to whiten or brighten kaolin clay and increase its value. Because all uranium and plutonium compounds are slightly magnetic, HGMS can be used to separate these contaminants from non-magnetic soils. A Cooperative Research and Development Agreement (CRADA) was signed in 1992 between Los Alamos National Laboratory (LANL) and Lockheed Environmental Systems and Technologies Company (LESAT) to develop HGMS for soil decontamination. This paper reports progress and describes the HGMS technology.

Avens, L.R.; Worl, L.A.; deAguero, K.J.; Padilla, D.D.; Prenger, F.C.; Stewart, W.F.; Hill, D.D. (Los Alamos National Lab., NM (United States)); Tolt, T.L. (Lockheed Environmental Systems and Technologies (United States))

1993-01-01

33

Magnetic separation for soil decontamination  

SciTech Connect

High gradient magnetic separation (HGMS) is a physical separation process that is used to extract magnetic particles from mixtures. The technology is used on a large scale in the kaolin clay industry to whiten or brighten kaolin clay and increase its value. Because all uranium and plutonium compounds are slightly magnetic, HGMS can be used to separate these contaminants from non-magnetic soils. A Cooperative Research and Development Agreement (CRADA) was signed in 1992 between Los Alamos National Laboratory (LANL) and Lockheed Environmental Systems and Technologies Company (LESAT) to develop HGMS for soil decontamination. This paper reports progress and describes the HGMS technology.

Avens, L.R.; Worl, L.A.; deAguero, K.J.; Padilla, D.D.; Prenger, F.C.; Stewart, W.F.; Hill, D.D. [Los Alamos National Lab., NM (United States); Tolt, T.L. [Lockheed Environmental Systems and Technologies (United States)

1993-02-01

34

Hybrid magnet devices for molecule manipulation and small scale high gradient-field applications  

DOEpatents

The present disclosure provides a high performance hybrid magnetic structure made from a combination of permanent magnets and ferromagnetic pole materials which are assembled in a predetermined array. The hybrid magnetic structure provides means for separation and other biotechnology applications involving holding, manipulation, or separation of magnetizable molecular structures and targets. Also disclosed are hybrid magnetic tweezers able to exert approximately 1 nN of force to 4.5 .mu.m magnetic bead. The maximum force was experimentally measured to be .about.900 pN which is in good agreement with theoretical estimations and other measurements. In addition, a new analysis scheme that permits fast real-time position measurement in typical geometry of magnetic tweezers has been developed and described in detail.

Humphries, David E. (El Cerrito, CA); Hong, Seok-Cheol (Seoul, KR); Cozzarelli, legal representative, Linda A. (Berkeley, CA); Pollard, Martin J. (El Cerrito, CA); Cozzarelli, Nicholas R. (Berkeley, CA)

2009-01-06

35

Evidence of Magnetic Breakdown on the Defects With Thermally Suppressed Critical Field in High Gradient SRF Cavities  

SciTech Connect

At SRF 2011 we presented the study of quenches in high gradient SRF cavities with dual mode excitation technique. The data differed from measurements done in 80's that indicated thermal breakdown nature of quenches in SRF cavities. In this contribution we present analysis of the data that indicates that our recent data for high gradient quenches is consistent with the magnetic breakdown on the defects with thermally suppressed critical field. From the parametric fits derived within the model we estimate the critical breakdown fields.

Eremeev, Grigory [JLAB; Palczewski, Ari [JLAB

2013-09-01

36

Some effects of high- gradient magnetic field on tropism of roots of higher plants  

NASA Astrophysics Data System (ADS)

The perception of gravity in living organisms is mostly based on the response of the gravisensing system to displacement of some specific mass caused by gravitational force. According to the starch-statolith hypothesis the amyloplasts play the role of specific mass in gravisensing cells of higher plants. Kuznetsov & Hasenstein (1996) have demonstrated that the high-gradient magnetic field (HGMF) exerts a directional ponderomotive force on diamagnetic substances, in particular, statoliths. This effect of the HGMF causes root response similar to that produced by the change in gravity vector. Their studies supported the starch-statolith hypothesis and showed that ponderomotive force can be used to modify force acting on statoliths by manipulating statolith locations within gravisensing cells. We have designed the HGMF facility that allows for generating the HGMF and analyzing its effects on higher plants' roots. It records by videosystem and measures with the help of image analysis software the parameters of kinetics of root bending under both the HGMF action and gravistimulation. Two species of plants (pea and cress) have been examined. The main results of the work are the following: 1) The magnetotropic effect of HGMF on root growth was found for both species. 2) The critical value of ponderomotive force that caused the magnetotropic effect was estimated by modeling the magnetic field spatial distribution in the region of root apex. 3) The electron-microscopic analysis of statocytes after the HGMF treatment was carried out. The displacement of amyloplasts in root statocytes of two species of plants in HGMF was firstly demonstrated at the ultrastructural level. 4) Spatial distribution of exogenous proton fluxes (pH) along the roots was studied. The changes in pH distribution along curvature zone and apices of roots were revealed in the HGMF. It is known that application of HGMFs or strong uniform magnetic fields may influence ion transport due to Ampere force. It results in proton asymmetry relative to the root axis because the extent of changed H+ fluxes will depend on the intensity of the magnetic field. Thus, strong magnetic field can elicit asymmetric radial ion fluxes that, in turn, may be perceived as a directional stimulus. The estimates of these effects and the possible experiments to test these effects are proposed. 5) A theoretical analysis and modeling of optimal magnet configurations for the HGMF experiments as well as calculation of spatial distribution of ponderomotive force were carried out. The results are important for the qualitative treatment of the HGMF effects.

Kondrachuk, A.; Belyavskaya, N.

37

Permanently magnetized high gradient magnetic air filters for the nuclear industry  

Microsoft Academic Search

This paper describes the structure and testing of two novel permanently magnetized magnetic filters for fine radioactive material. In the first filter the holes in the filter are left open as capture proceeds which means the pressure drop builds up only slowly. This filter is not suitable for composite particles which can be broken by mechanical forces. The second filter

J. H. P. Watson

1995-01-01

38

Ultrastructure of pea and cress root statocytes exposed to high gradient magnetic field  

NASA Astrophysics Data System (ADS)

As it was demonstrated by Kuznetsov & Hasenstein (1996) the high gradient magnetic field (HGMF) can produce a ponderomotive force that results in displacements of amyloplasts and causes the root response similar to the graviresponse. It was suggested that the HGMF could allow to imitate the effects of gravity in microgravity and/or change them in laboratory conditions correspondingly, as well as to study statolith-related processes in graviperception. Therefore, the correlation between the direction of the ponderomotive force resulting in statolith displacements and the direction of the HGMF-induced plant curvature can be the serious argument to support this suggestion and needs the detailed ultrastructural analysis. Seeds of dicotyledon Pisum sativum L. cv. Damir-2 and monocotyledon Lepidium sativum L. cv. P896 were soaked and grown in a vertical position on moist filter paper in chambers at room temperature. Tips of primary roots of vertical control, gravistimulated and exposed to HGMF seedlings were fixed for electron microscopy using conventional techniques. At ultrastructural level, we observed no significant changes in the volume of the individual statocytes or amyloplasts, relative volumes of cellular organelles (except vacuoles), number of amyloplasts per statocyte or surface area of endoplasmic reticulum. No consistent contacts between amyloplasts and any cellular structures, including plasma membrane, were revealed at any stage of magneto- and gravistimulation. By 5 min after onset of magnetostimulation, amyloplasts were located along cell wall distant from magnets. In HGMF, the locations of amyloplasts in columella cells were similar to those in horizontally-oriented roots up to 1 h stimulation. In the latter case, there were sometimes cytoplasmic spherical bodies with a dense vesicle-rich cytoplasm in pea statocytes, which were absent in seedlings exposed to HGMF. In cress root statocytes, both gravi- and magnetostimulation were found to cause the appearance of significant amounts of electron-dense granules in the cytoplasm and the nucleus (particularly, in the nucleolus); the effect was most evident in HGMF. Testing the chemical composition of such deposits is going on. The data presented statocyte responses indicate similarity the effects of magneto- and gravistimulation at the ultrastructural level. Thus, the root curvature in HGMF is the plant response to displacement of amyloplasts by ponderomotive force, which can serve as tool for investigation of graviperception mechanism and can provide directional stimulus for plant growth in microgravity. (Financial support by STCU: NN-13R).

Belyavskaya, N. A.; Chernishov, V. I.; Polishchuk, O. V.; Kondrachuk, A. V.

39

Down-regulation of adipogenesis of mesenchymal stem cells by oscillating high-gradient magnetic fields and mechanical vibration  

NASA Astrophysics Data System (ADS)

Nowadays, the focus in medicine on molecular genetics has resulted in a disregard for the physical basis of treatment even though many diseases originate from changes in cellular mechanics. Perturbations of the cellular nanomechanics promote pathologies, including cardiovascular disease and cancer. Furthermore, whilst the biological and therapeutic effects of magnetic fields are a well-established fact, to date the underlying mechanisms remain obscure. Here, we show that oscillating high-gradient magnetic field (HGMF) and mechanical vibration affect adipogenic differentiation of mesenchymal stem cells by the transmission of mechanical stress to the cell cytoskeleton, resulting in F-actin remodelling and subsequent down-regulation of adipogenic genes adiponectin, PPAR?, and AP2. Our findings propose an insight into the regulation of cellular nanomechanics, and provide a basis for better controlled down-regulation of stem cell adipogenesis by HGMF, which may facilitate the development of challenging therapeutic strategies suitable for the remote control of biological systems.

Zablotskii, V.; Lunov, O.; Novotná, B.; Churpita, O.; Trošan, P.; HoláÅ, V.; Syková, E.; Dejneka, A.; Kubinová, Š.

2014-09-01

40

Computational modeling of magnetic nanoparticle targeting to stent surface under high gradient field  

NASA Astrophysics Data System (ADS)

A multi-physics model was developed to study the delivery of magnetic nanoparticles (MNPs) to the stent-implanted region under an external magnetic field. The model is firstly validated by experimental work in literature. Then, effects of external magnetic field strength, magnetic particle size, and flow velocity on MNPs' targeting and binding have been analyzed through a parametric study. Two new dimensionless numbers were introduced to characterize relative effects of Brownian motion, magnetic force induced particle motion, and convective blood flow on MNPs motion. It was found that larger magnetic field strength, bigger MNP size, and slower flow velocity increase the capture efficiency of MNPs. The distribution of captured MNPs on the vessel along axial and azimuthal directions was also discussed. Results showed that the MNPs density decreased exponentially along axial direction after one-dose injection while it was uniform along azimuthal direction in the whole stented region (averaged over all sections). For the beginning section of the stented region, the density ratio distribution of captured MNPs along azimuthal direction is center-symmetrical, corresponding to the center-symmetrical distribution of magnetic force in that section. Two different generation mechanisms are revealed to form four main attraction regions. These results could serve as guidelines to design a better magnetic drug delivery system.

Wang, Shunqiang; Zhou, Yihua; Tan, Jifu; Xu, Jiang; Yang, Jie; Liu, Yaling

2014-03-01

41

Validation of high gradient magnetic field based drug delivery to magnetizable implants under flow.  

PubMed

The drug-eluting stent's increasingly frequent occurrence late stage thrombosis have created a need for new strategies for intervention in coronary artery disease. This paper demonstrates further development of our minimally invasive, targeted drug delivery system that uses induced magnetism to administer repeatable and patient specific dosages of therapeutic agents to specific sites in the human body. Our first aim is the use of magnetizable stents for the prevention and treatment of coronary restenosis; however, future applications include the targeting of tumors, vascular defects, and other localized pathologies. Future doses can be administered to the same site by intravenous injection. This implant-based drug delivery system functions by placement of a weakly magnetizable stent or implant at precise locations in the cardiovascular system, followed by the delivery of magnetically susceptible drug carriers. The stents are capable of applying high local magnetic field gradients within the body, while only exposing the body to a modest external field. The local gradients created within the blood vessel create the forces needed to attract and hold drug-containing magnetic nanoparticles at the implant site. Once these particles are captured, they are capable of delivering therapeutic agents such as antineoplastics, radioactivity, or biological cells. PMID:18270000

Forbes, Zachary G; Yellen, Benjamin B; Halverson, Derek S; Fridman, Gregory; Barbee, Kenneth A; Friedman, Gary

2008-02-01

42

[Separation of magnetic bacteria by using a magnetic separator].  

PubMed

A magnetic separator was used to separate magnetic bacteria based on their magnetotactic characteristics. Acidithiobacillus ferrooxidans, a bacterium that could synthesize intra-cellular nanometer magnetic particles, was investigated as an example. Strong magnetic and weak magnetic cells were separated and collected. On average, the number of the magnetic particles present in the strong magnetic cells is more than that of the weak magnetic cells. Moreover, semisolid-plate magnetophoresis showed that the magnetotaxis of strong magnetic cells was stronger than the weak magnetic cells. These results suggest that the magnetic separator can be used to isolate the magnetic bacteria, which will facilitate the research of magnetic bacteria. PMID:20432949

Liu, Xinxing; Guo, Ning; Yang, Yingjie; Liang, Wanjie; Zhang, Jian

2010-02-01

43

Magnetophoretic velocimetry of manganese(II) in a single microdroplet in a flow system under a high gradient magnetic field generated with a superconducting magnet.  

PubMed

An experimental system for magnetophoretic velocimetry, which could determine the volume magnetic susceptibility of a single particle dispersed in a liquid phase from a magnetophoretic velocity, has been developed. A micrometer-sized high-gradient magnetic field could be generated in a capillary by a pair of iron pole pieces in a superconducting magnet (10 T). The magnetophoretic behavior of a single particle in a capillary flow system was investigated under the inhomogeneous magnetic field. From the magnetophoretic velocity of a polystyrene latex particle dispersed in a MnCl2 aqueous solution, the product of the magnetic flux density and the gradient, B(dB/dx), was determined as a function of the position along the capillary. The maximum value of B(dB/dx) was 4.7 x 10(4) T2 m(-1), which was approximately 100 times higher than that obtained by two Nd-Fe-B permanent magnets (0.4 T). Organic droplets extracting manganese(II) with 2-thenoyltrifluoroacetone and tri-n-octylphosphine oxide from MnCl2 solution were used as test samples. The difference of the volume magnetic susceptibility between the droplet and the medium could be determined from the magnetophoretic velocity. This method allowed us to continuously measure a volume magnetic susceptibility of 10-6 level for a picoliter droplet and to determine manganese(II) in the single droplet at the attomole level. PMID:12380826

Suwa, Masayori; Watarai, Hitoshi

2002-10-01

44

A feasibility study of magnetic separation of magnetic nanoparticle for forward osmosis.  

PubMed

It was recently reported that a UK company has developed a naturally non-toxic magnetoferritin to act as a draw solute for drawing water in forward osmosis process. The gist of this technology is the utilization of the magnetic nanoparticle and high-gradient magnetic separation for draw solute separation and reuse. However, any demonstration on this technology has not been reported yet. In this study, a feasibility test of magnetic separation using magnetic nanoparticle was therefore performed to investigate the possibility of magnetic separation in water treatment such as desalination. Basically, a magnetic separation system consisted of a column packed with a bed of magnetically susceptible wools placed between the poles of electromagnet and Fe3O4 magnetic nanoparticle was used as a model nanoparticle. The effect of nanoparticle size to applied magnetic field in separation column was experimentally investigated and the magnetic field distribution in a magnet gap and the magnetic field gradient around stainless steel wool wire were analyzed through numerical simulation. The amount of magnetic nanoparticle captured in the separator column increased as the magnetic field strength and particle size increased. As a result, if magnetic separation is intended to be used for draw solute separation and reuse, both novel nanoparticle and large-scale high performance magnetic separator must be developed. PMID:22097022

Kim, Y C; Han, S; Hong, S

2011-01-01

45

Optimizing colloidal dispersity of magnetic nanoparticles based on magnetic separation with magnetic nanowires array  

NASA Astrophysics Data System (ADS)

Based on sharp geometry of Ni nanowires, we developed a novel high-gradient magnetic separator that was composed of a nanowires array and a uniform magnetic field. When suspension of magnetic nanoparticles (MNPs) flowed through it, the relatively large nanoparticles or clusters were removed from the suspension so that the size distribution can be improved. The separation resulted from magnetic force so that extra molecules or solvents were unnecessary to add. The performance was proved by scanned electron microscopy characterization and dynamic light scattering measurement. The improvement in magnetic colloidal dispersivity is important for the biomedical application of MNPs. Our results may also play a role in microfluidic application and nanoparticle-based detection.

Sun, Jianfei; He, Miaomiao; Liu, Xuan; Gu, Ning

2014-09-01

46

Optimizing colloidal dispersity of magnetic nanoparticles based on magnetic separation with magnetic nanowires array  

NASA Astrophysics Data System (ADS)

Based on sharp geometry of Ni nanowires, we developed a novel high-gradient magnetic separator that was composed of a nanowires array and a uniform magnetic field. When suspension of magnetic nanoparticles (MNPs) flowed through it, the relatively large nanoparticles or clusters were removed from the suspension so that the size distribution can be improved. The separation resulted from magnetic force so that extra molecules or solvents were unnecessary to add. The performance was proved by scanned electron microscopy characterization and dynamic light scattering measurement. The improvement in magnetic colloidal dispersivity is important for the biomedical application of MNPs. Our results may also play a role in microfluidic application and nanoparticle-based detection.

Sun, Jianfei; He, Miaomiao; Liu, Xuan; Gu, Ning

2015-02-01

47

Magnetic precipitate separation for Ni plating waste liquid using HTS bulk magnets  

NASA Astrophysics Data System (ADS)

The magnetic separation experiment for recycling the nickel-bearing precipitates in the waste liquid from the electroless plating processes has been practically conducted under the high gradient magnetic separation technique with use of the face-to-face HTS bulk magnet system. A couple of facing magnetic poles containing Sm123 bulk superconductors were activated through the pulsed field magnetization process to 1.86 T at 38 K and 2.00 T at 37 K, respectively. The weakly magnetized metallic precipitates of Ni crystals and Ni-P compounds deposited from the waste solution after heating it and pH controlling. The high gradient magnetic separation technique was employed with the separation channels filled with the stainless steel balls with dimension of 1 and 3 mm in diameter, which periodically moved between and out of the facing magnetic poles. The Ni-bearing precipitates were effectively attracted to the magnetized ferromagnetic balls. We have succeeded in obtaining the separation ratios over 90% under the flow rates less than 1.35 L/min.

Oka, T.; Kimura, T.; Mimura, D.; Fukazawa, H.; Fukui, S.; Ogawa, J.; Sato, T.; Ooizumi, M.; Yokoyama, K.; Tsujimura, M.; Terasawa, T.

2013-01-01

48

Magnetic microgels, a promising candidate for enhanced magnetic adsorbent particles in bioseparation: synthesis, physicochemical characterization, and separation performance.  

PubMed

For specific applications in the field of high gradient magnetic separation of biomaterials, magnetic nanoparticle clusters of controlled size and high magnetic moment in an external magnetic field are of particular interest. We report the synthesis and characterization of magnetic microgels designed for magnetic separation purposes, as well as the separation efficiency of the obtained microgel particles. High magnetization magnetic microgels with superparamagnetic behaviour were obtained in a two-step synthesis procedure by a miniemulsion technique using highly stable ferrofluid on a volatile nonpolar carrier. Spherical clusters of closely packed hydrophobic oleic acid-coated magnetite nanoparticles were coated with cross linked polymer shells of polyacrylic acid, poly-N-isopropylacrylamide, and poly-3-acrylamidopropyl trimethylammonium chloride. The morphology, size distribution, chemical surface composition, and magnetic properties of the magnetic microgels were determined using transmission electron microscopy, X-ray photoelectron spectroscopy, and vibrating sample magnetometry. Magnetically induced phase condensation in aqueous suspensions of magnetic microgels was investigated by optical microscopy and static light scattering. The condensed phase consists of elongated oblong structures oriented in the direction of the external magnetic field and may grow up to several microns in thickness and tens or even hundreds of microns in length. The dependence of phase condensation magnetic supersaturation on the magnetic field intensity was determined. The experiments using high gradient magnetic separation show high values of separation efficiency (99.9-99.97%) for the magnetic microgels. PMID:25519891

Turcu, Rodica; Socoliuc, Vlad; Craciunescu, Izabell; Petran, Anca; Paulus, Anja; Franzreb, Matthias; Vasile, Eugeniu; Vekas, Ladislau

2015-01-21

49

The physics of magnetic separation  

NASA Astrophysics Data System (ADS)

Current activity in the field of magnetic separation is reviewed in fundamental terms. The diverse subject matter is ordered into four main groupings whose characteristics are described in terms of numerous devices, both of present-day and historical significance. Existing as well as potential areas of scientific and commercial operation are discussed. The basic principles of recent major developments in high intensity magnetic separation are closely examined.

Parker, M. R.

1977-05-01

50

Magnetic particle separation using controllable magnetic force switches  

NASA Astrophysics Data System (ADS)

Magnetic particle separation is very important in biomedical applications. In this study, a magnetic particle microseparator is proposed that uses micro magnets to produce open/closed magnetic flux for switching on/off the separation. When all magnets are magnetized in the same direction, the magnetic force switch for separation is on; almost all magnetic particles are trapped in the channel side walls and the separation rate can reach 95%. When the magnetization directions of adjacent magnets are opposite, the magnetic force switch for separation is off, and most magnetic particles pass through the microchannel without being trapped. For the separation of multi-sized magnetic particles, the proposed microseparator is numerically demonstrated to have high separation rate.

Wei, Zung-Hang; Lee, Chiun-Peng; Lai, Mei-Feng

2010-01-01

51

Method of magnetic separation and apparatus therefore  

NASA Technical Reports Server (NTRS)

An apparatus for magnetically separating and collecting particulate matter fractions of a raw sample according to relative magnetic susceptibilities of each fraction so collected is disclosed. The separation apparatus includes a splitter which is used in conjunction with a magnetic separator for achieving the desired fractionation.

Oder, Robin R. (Inventor)

1991-01-01

52

Magnetic separation techniques: their application to medicine  

Microsoft Academic Search

Whilst separation techniques relying on gravitational forces have become relatively sophisticated in their application to biology the same is not true for magnetic separation procedures. The use of the latter has been limited to the few cells which contain paramagnetic iron. However with the development of several different types of magnetic particles and selective delivery system (e.g. monoclonal antibodies) the

J. T. Kemsheadl; J. Ugelstad

1985-01-01

53

Magnetically Enhanced Solid-Liquid Separation  

Microsoft Academic Search

DuPont is developing an entirely new method of solid-liquid filtration involving the use of magnetic fields and magnetic field gradients. The new hybrid process, entitled Magnetically Enhanced Solid-Liquid Separation (MESLS), is designed to improve the de-watering kinetics and reduce the residual moisture content of solid particulates mechanically separated from liquid slurries. Gravitation, pressure, temperature, centrifugation, and fluid dynamics have dictated

C. M. Rey; K. Keller; B. Fuchs

2005-01-01

54

Magnetic separation in water pollution control  

Microsoft Academic Search

Magnetic separation as applied to waterborne contaminants is successful in reducing the solids content of a water sample and in removing the dissolved orthophosphate from the aqueous slurry. The contaminants are chemically associated with a magnetic seeding material, and subsequent removal of this seed sweeps the pollutants from the system. The advantage of this form of treatment over conventional techniques

CHRISTOPHER DE LATOUR

1973-01-01

55

A PURPOSE ORIENTED MAGNETIC SEPARATOR: SKIMMER  

SciTech Connect

A magnetic separator was designed to selectively separate fine-liberated magnetite. The conceptual design was simulated using CFD techniques. A separator tank was fabricated and a magnetic drum was used to capture magnetic particles. The initial tank design was modified to eliminate application oriented problems. The new separator was able to produce a fine product as a concentrate at relatively high feed rates. A plant simulation showed that such a device could lower circulating loads around ball mills by 16%, thereby creating room for a 5-8% increase in throughput at the same energy level. However, it was concluded that further improvements in terms of both size and mineral selectivity are needed to have a marketable product.

Salih Ersayin

2005-08-09

56

Magnetically Enhanced Solid-Liquid Separation  

NASA Astrophysics Data System (ADS)

DuPont is developing an entirely new method of solid-liquid filtration involving the use of magnetic fields and magnetic field gradients. The new hybrid process, entitled Magnetically Enhanced Solid-Liquid Separation (MESLS), is designed to improve the de-watering kinetics and reduce the residual moisture content of solid particulates mechanically separated from liquid slurries. Gravitation, pressure, temperature, centrifugation, and fluid dynamics have dictated traditional solid-liquid separation for the past 50 years. The introduction of an external field (i.e. the magnetic field) offers the promise to manipulate particle behavior in an entirely new manner, which leads to increased process efficiency. Traditional solid-liquid separation typically consists of two primary steps. The first is a mechanical step in which the solid particulate is separated from the liquid using e.g. gas pressure through a filter membrane, centrifugation, etc. The second step is a thermal drying process, which is required due to imperfect mechanical separation. The thermal drying process is over 100-200 times less energy efficient than the mechanical step. Since enormous volumes of materials are processed each year, more efficient mechanical solid-liquid separations can be leveraged into dramatic reductions in overall energy consumption by reducing downstream drying requirements have a tremendous impact on energy consumption. Using DuPont's MESLS process, initial test results showed four very important effects of the magnetic field on the solid-liquid filtration process: 1) reduction of the time to reach gas breakthrough, 2) less loss of solid into the filtrate, 3) reduction of the (solids) residual moisture content, and 4) acceleration of the de-watering kinetics. These test results and their potential impact on future commercial solid-liquid filtration is discussed. New applications can be found in mining, chemical and bioprocesses.

Rey, C. M.; Keller, K.; Fuchs, B.

2005-07-01

57

Particle acceleration at a reconnecting magnetic separator  

NASA Astrophysics Data System (ADS)

Context. While the exact acceleration mechanism of energetic particles during solar flares is (as yet) unknown, magnetic reconnection plays a key role both in the release of stored magnetic energy of the solar corona and the magnetic restructuring during a flare. Recent work has shown that special field lines, called separators, are common sites of reconnection in 3D numerical experiments. To date, 3D separator reconnection sites have received little attention as particle accelerators. Aims: We investigate the effectiveness of separator reconnection as a particle acceleration mechanism for electrons and protons. Methods: We study the particle acceleration using a relativistic guiding-centre particle code in a time-dependent kinematic model of magnetic reconnection at a separator. Results: The effect upon particle behaviour of initial position, pitch angle, and initial kinetic energy are examined in detail, both for specific (single) particle examples and for large distributions of initial conditions. The separator reconnection model contains several free parameters, and we study the effect of changing these parameters upon particle acceleration, in particular in view of the final particle energy ranges that agree with observed energy spectra.

Threlfall, J.; Neukirch, T.; Parnell, C. E.; Eradat Oskoui, S.

2015-02-01

58

Development of magnetic separation system of magnetoliposomes  

NASA Astrophysics Data System (ADS)

The magnetic separation technology using sub-microsized ferromagnetic particle is indispensable in many areas of medical biosciences. For example, ferromagnetic particles (200-500 nm) are widely used for cell sorting in stem cell research with the use of cell surface-specific antigens. Nanosized ferromagnetic particles (10-20 nm) have been suggested as more suitable in drug delivery studies given their efficiency of tissue penetration, however, the magnetic separation method for them has not been established. One of the major reasons is that magnetic force acting on the object particles decreases drastically as a particle diameter becomes small. In this study, magnetic force acting on the targets was enhanced by the combination of superconducting magnet and the filter consisting of ferromagnetic particle. By doing so, we confirmed that Fe 3O 4 of 20 nm in diameter was trapped in the magnetic filter under an external magnetic field of 0.5 T. Fe 3O 4 encapsulated with phospholipid liposomes of 200 nm in diameter was also shown to be trapped as external magnetic field of 1.5 T, but not of 0.5 T. We also showed the result of particle trajectory calculation which emulated well the experimental data.

Nakao, R.; Matuo, Y.; Mishima, F.; Taguchi, T.; Maenosono, S.; Nishijima, S.

2009-10-01

59

Dual Magnetic Separator for TRI$?$P  

E-print Network

The TRI$\\mu$P facility, under construction at KVI, requires the production and separation of short-lived and rare isotopes. Direct reactions, fragmentation and fusion-evaporation reactions in normal and inverse kinematics are foreseen to produce nuclides of interest with a variety of heavy-ion beams from the superconducting cyclotron AGOR. For this purpose, we have designed, constructed and commissioned a versatile magnetic separator that allows efficient injection into an ion catcher, i.e., gas-filled stopper/cooler or thermal ionizer, from which a low energy radioactive beam will be extracted. The separator performance was tested with the production and clean separation of $^{21}$Na ions, where a beam purity of 99.5% could be achieved. For fusion-evaporation products, some of the features of its operation as a gas-filled recoil separator were tested.

G. P. A. Berg; O. C. Dermois; U. Dammalapati; P. Dendooven M. N. Harakeh; K. Jungmann; C. J. G. Onderwater; A. Rogachevskiy; M. Sohani; E. Traykov; L. Willmann; H. W. Wilschut

2006-01-16

60

Multistage Magnetic Separator of Cells and Proteins  

NASA Technical Reports Server (NTRS)

The multistage electromagnetic separator for purifying cells and magnetic particles (MAGSEP) is a laboratory apparatus for separating and/or purifying particles (especially biological cells) on the basis of their magnetic susceptibility and magnetophoretic mobility. Whereas a typical prior apparatus based on similar principles offers only a single stage of separation, the MAGSEP, as its full name indicates, offers multiple stages of separation; this makes it possible to refine a sample population of particles to a higher level of purity or to categorize multiple portions of the sample on the basis of magnetic susceptibility and/or magnetophoretic mobility. The MAGSEP includes a processing unit and an electronic unit coupled to a personal computer. The processing unit includes upper and lower plates, a plate-rotation system, an electromagnet, an electromagnet-translation system, and a capture-magnet assembly. The plates are bolted together through a roller bearing that allows the plates to rotate with respect to each other. An interface between the plates acts as a seal for separating fluids. A lower cuvette can be aligned with as many as 15 upper cuvette stations for fraction collection during processing. A two-phase stepping motor drives the rotation system, causing the upper plate to rotate for the collection of each fraction of the sample material. The electromagnet generates a magnetic field across the lower cuvette, while the translation system translates the electromagnet upward along the lower cuvette. The current supplied to the electromagnet, and thus the magnetic flux density at the pole face of the electromagnet, can be set at a programmed value between 0 and 1,400 gauss (0.14 T). The rate of translation can be programmed between 5 and 2,000 m/s so as to align all sample particles in the same position in the cuvette. The capture magnet can be a permanent magnet. It is mounted on an arm connected to a stepping motor. The stepping motor rotates the arm to position the capture magnet above the upper cuvette into which a fraction of the sample is collected. The electronic unit includes a power switch, power-supply circuitry that accepts 110-Vac input power, an RS-232 interface, and status lights. The personal computer runs the MAGSEP software and controls the operation of the MAGSEP through the RS-232 interface. The status of the power, the translating electromagnet, the capture magnet, and the rotation of the upper plate are indicated in a graphical user interface on the computer screen.

Barton, Ken; Ainsworth, Mark; Daily, Bruce; Dunn, Scott; Metz, Bill; Vellinger, John; Taylor, Brock; Meador, Bruce

2005-01-01

61

Asymmetric Uncertainty Expression for High Gradient Aerodynamics  

NASA Technical Reports Server (NTRS)

When the physics of the flow around an aircraft changes very abruptly either in time or space (e.g., flow separation/reattachment, boundary layer transition, unsteadiness, shocks, etc), the measurements that are performed in a simulated environment like a wind tunnel test or a computational simulation will most likely incorrectly predict the exact location of where (or when) the change in physics happens. There are many reasons for this, includ- ing the error introduced by simulating a real system at a smaller scale and at non-ideal conditions, or the error due to turbulence models in a computational simulation. The un- certainty analysis principles that have been developed and are being implemented today do not fully account for uncertainty in the knowledge of the location of abrupt physics changes or sharp gradients, leading to a potentially underestimated uncertainty in those areas. To address this problem, a new asymmetric aerodynamic uncertainty expression containing an extra term to account for a phase-uncertainty, the magnitude of which is emphasized in the high-gradient aerodynamic regions is proposed in this paper. Additionally, based on previous work, a method for dispersing aerodynamic data within asymmetric uncer- tainty bounds in a more realistic way has been developed for use within Monte Carlo-type analyses.

Pinier, Jeremy T

2012-01-01

62

Coupled particle-fluid transport and magnetic separation in microfluidic systems with passive magnetic functionality  

NASA Astrophysics Data System (ADS)

A study is presented of coupled particle-fluid transport and field-directed particle capture in microfluidic systems with passive magnetic functionality. These systems consist of a microfluidic flow cell on a substrate that contains embedded magnetic elements. Two systems are considered that utilize soft- and hard-magnetic elements, respectively. In the former, an external field is applied to magnetize the elements, and in the latter, they are permanently magnetized. The field produced by the magnetized elements permeates into the flow cell giving rise to an attractive force on magnetic particles that flow through it. The systems are studied using a novel numerical/closed-form modelling approach that combines numerical transport analysis with closed-form field analysis. Particle-fluid transport is computed using computational fluid dynamics (CFD), while the magnetic force that governs particle capture is obtained in closed form. The CFD analysis takes into account dominant particle forces and two-way momentum transfer between the particles and the fluid. The two-way particle-fluid coupling capability is an important feature of the model that distinguishes it from more commonly used and simplified one-way coupling analysis. The model is used to quantify the impact of two-way particle-fluid coupling on both the capture efficiency and the flow pattern in the systems considered. Many effects such as particle-induced flow-enhanced capture efficiency and flow circulation are studied that cannot be predicted using one-way coupling analysis. In addition, dilute particle dispersions are shown to exhibit significant localized particle-fluid coupling near the capture regions, which contradicts the commonly held view that two-way coupling can be ignored when analysing high-gradient magnetic separation involving such particle systems. Overall, the model demonstrates that two-way coupling needs to be taken into account for rigorous predictions of capture efficiency, especially for applications involving high particle loading and/or low flow rates. It is computationally more efficient and accurate than purely numerical models and should prove useful for the rational design and optimization of novel magnetophoretic microsystems.

Khashan, Saud A.; Furlani, Edward P.

2013-03-01

63

Colloidal magnetic fluids as extractants for chemical processing applications  

E-print Network

The feasibility of using high gradient magnetic separation (HGMS) to separate the Fe?0? nanoparticles was studied in this work. We present a general model for nanoparticle capture based on calculating the limit of static ...

Moeser, Geoffrey D. (Geoffery Dawson), 1976-

2003-01-01

64

Magnetic separation techniques in diagnostic microbiology.  

PubMed Central

The principles of magnetic separation aided by antibodies or other specific binding molecules have been used for isolation of specific viable whole organisms, antigens, or nucleic acids. Whereas growth on selective media may be helpful in isolation of a certain bacterial species, immunomagnetic separation (IMS) technology can isolate strains possessing specific and characteristic surface antigens. Further separation, cultivation, and identification of the isolate can be performed by traditional biochemical, immunologic, or molecular methods. PCR can be used for amplification and identification of genes of diagnostic importance for a target organism. The combination of IMS and PCR reduces the assay time to several hours while increasing both specificity and sensitivity. Use of streptavidin-coated magnetic beads for separation of amplified DNA fragments, containing both biotin and a signal molecule, has allowed for the conversion of the traditional PCR into an easy-to-read microtiter plate format. The bead-bound PCR amplicons can also easily be sequenced in an automated DNA sequencer. The latter technique makes it possible to obtain sequence data of 300 to 600 bases from 20 to 30 strains, starting with clinical samples, within 12 to 24 h. Sequence data can be used for both diagnostic and epidemiologic purposes. IMS has been demonstrated to be a useful method in diagnostic microbiology. Most recent publications describe IMS as a method for enhancing the specificity and sensitivity of other detection systems, such as PCR, and providing considerable savings in time compared with traditional diagnostic systems. The relevance to clinical diagnosis has, however, not yet been fully established for all of these new test principles. In the case of PCR, for example, the presence of specific DNA in a food sample does not demonstrate the presence of a live organism capable of inducing a disease. However, all tests offering increased sensitivity and specificity of detection, combined with reduced time of analysis, have to be seriously evaluated. Images PMID:8118790

Olsvik, O; Popovic, T; Skjerve, E; Cudjoe, K S; Hornes, E; Ugelstad, J; Uhlén, M

1994-01-01

65

High Gradient Two-Beam Electron Accelerator  

SciTech Connect

A high-gradient two-beam electron accelerator structure using detuned cavities is described. A self-consistent theory based on a circuit model is presented to calculate idealized acceleration gradient, transformer ratio, and efficiency for energy transfer from the drive beam to the accelerated beam. Experimental efforts are being carried out to demonstrate this acceleration concept.

Jiang, Y. [Beam Physics Laboratory, Yale University, 272 Whitney Ave., New Haven, CT 06511 (United States); Kazakov, S. Yu. [Omega-P, Inc., 258 Bradley St., New Haven, CT 06510 (United States); Fermi National Accelerator Laboratory, Batavia, IL 60510 (United States); Kuzikov, S. V. [Omega-P, Inc., 258 Bradley St., New Haven, CT 06510 (United States); Institute of Applied Physics, Nizhny Novgorod, 603600 (Russian Federation); Hirshfield, J. L. [Beam Physics Laboratory, Yale University, 272 Whitney Ave., New Haven, CT 06511 (United States); Omega-P, Inc., 258 Bradley St., New Haven, CT 06510 (United States)

2010-11-04

66

High-gradient continuous-casting furnace  

NASA Technical Reports Server (NTRS)

High gradient allows rapid growth rates in directionally-solidified eutectic alloys. Furnace design permits cost reductions in directional solidification process through its increased solidification rates, which reduces melt/mold interaction. It produces structural engineering materials for any application requiring properties directionally-solidified eutectic materials.

Scheuermann, C. M.; Flemings, M. C.; Neff, M. A.; Rickinson, B. A.; Young, K. P.

1979-01-01

67

A Parametric Study of a Portable Magnetic Separator for Separation of Nanospheres from Circulatory System  

Microsoft Academic Search

A portable magnetic separator was proposed for in-vivo biomedical applications. In this prototype design, a matrix of alternating, parallel magnetizable wires, and biocompatible tubing is immersed into an externally applied magnetic field. The wires are magnetized and high magnetic fields as well as field gradients are created to trap blood-borne flowing magnetic nanospheres in the tube. In this paper, a

Danny Bockenfeld; Haitao Chen; Michael D. Kaminski; Axel J. Rosengart; Dietmar Rempfer

2010-01-01

68

Creation of superconducting magnet separators for weakly magnetic mineral raw material processing  

SciTech Connect

The paper describes the investigations to work out the design and process parameters of superconducting commercial separators using laboratory units. The design features of the magnet system and the cryostat of the separator of the disk type for wet separation of weakly magnetic ores and non-ore materials are presented. The results of modelling the technological flowsheets for separation of various types of weakly magnetic material using SC magnetic separators are given. The necessity to further improve the magnetic separators in the direction of generation of the magnetic flux higher magnetic forces and densities is well-grounded.

Sidorenko, V.D.; Gerasimenko, I.A.; Kutin, A.M. [Mekhanobrchermet Inst., Krivoy Rog (Ukraine)] [Mekhanobrchermet Inst., Krivoy Rog (Ukraine); Yupherov, V.B.; Skibenko, Y.I. [National Research Centre Kharkov Physico-Technical Inst. (Ukraine)] [National Research Centre Kharkov Physico-Technical Inst. (Ukraine); Gladky, V.V. [Inst. of Low Temperature Physics and Engineering, Kharkov (Ukraine)] [Inst. of Low Temperature Physics and Engineering, Kharkov (Ukraine)

1996-07-01

69

Exploration of very high gradient cavities  

SciTech Connect

Several of the 9-cell ILC cavities processed at Jlab within ongoing ILC R&D program have shown interesting behavior at high fields, such as mode mixing and sudden field emission turn-on during quench. Equipped with thermometry and oscillating superleak transducer (OST) system for quench detection, we couple our RF measurements with local dissipation measurements. In this contribution we report on our findings with high gradient SRF cavities.

Grigory Eremeev

2011-07-01

70

MSWI boiler fly ashes: magnetic separation for material recovery.  

PubMed

Nowadays, ferrous materials are usually recovered from Municipal Solid Waste Incineration (MSWI) bottom ash by magnetic separation. To our knowledge, such a physical technique has not been applied so far to other MSWI residues. This study focuses thus on the applicability of magnetic separation on boiler fly ashes (BFA). Different types of magnet are used to extract the magnetic particles. We investigate the magnetic particle composition, as well as their leaching behaviour (EN 12457-1 leaching test). The magnetic particles present higher Cr, Fe, Mn and Ni concentration than the non-magnetic (NM) fraction. Magnetic separation does not improve the leachability of the NM fraction. To approximate industrial conditions, magnetic separation is also applied to BFA mixed with water by using a pilot. BFA magnetic separation is economically evaluated. This study globally shows that it is possible to extract some magnetic particles from MSWI boiler fly ashes. However, the magnetic particles only represent from 23 to 120 g/kg of the BFA and, though they are enriched in Fe, are composed of similar elements to the raw ashes. The industrial application of magnetic separation would only be profitable if large amounts of ashes were treated (more than 15 kt/y), and the process should be ideally completed by other recovery methods or advanced treatments. PMID:21306886

De Boom, Aurore; Degrez, Marc; Hubaux, Paul; Lucion, Christian

2011-07-01

71

Fundamental study of phosphor separation by controlling magnetic force  

NASA Astrophysics Data System (ADS)

The phosphor wastes consist of phosphors with different emission colors, green (LAP), red (YOX), blue (BAM) and white (HP). It is required to recover and reuse the rare earth phosphors with high market value. In this study, we tried to separate the phosphor using the magnetic separation by HTS bulk magnet utilizing the differences of magnetic susceptibility by the type of phosphors. We succeeded in the successive separation of HP with low market value from YOX and BAM including the rare earth using the magnetic Archimedes method. In this method, vertical and radial components of the magnetic force were used.

Wada, Kohei; Mishima, Fumihito; Akiyama, Yoko; Nishijima, Shigehiro

2013-11-01

72

Relativistic klystron research for high gradient accelerators  

SciTech Connect

Relativistic klystrons are being developed as a power source for high gradient accelerator applications which include large linear electron--positron colliders, compact accelerators, and FEL sources. We have attained 200MW peak power at 11.4 GHz from a relativistic klystron, and 140 MV/m longitudinal gradient in a short 11.4 GHz accelerator section. We report here on the design of our first klystrons, the results of our experiments so far, and some of our plans for the near future. 5 refs., 7 figs.

Allen, M.A.; Callin, R.S.; Deruyter, H.; Eppley, K.R.; Fowkes, W.R.; Herrmannsfeldt, W.B.; Higo, T.; Hoag, H.A.; Lavine, T.L.; Lee, T.G.

1988-06-01

73

SEPARATION OF VARIABLES AND THE XXZ GAUDIN MAGNET  

E-print Network

SEPARATION OF VARIABLES AND THE XXZ GAUDIN MAGNET E.G. KALNINS, V.B. KUZNETSOV and WILLARD MILLER, Minnesota 55455, USA. Abstract. In this work we generalise previous results connecting (rational) Gaudin the relationship between the separable systems and the Gaudin magnet [4,9] integrable systems models has been

Miller, Willard

74

Magnetic separation of micro-spheres from viscous biological fluids  

NASA Astrophysics Data System (ADS)

A magnetically based detoxification system is being developed as a therapeutic tool for selective and rapid removal of biohazards, i.e. chemicals and radioactive substances, from human blood. One of the key components of this system is a portable magnetic separator capable of separating polymer-based magnetic nano/micro-spheres from arterial blood flow in an ex vivo unit. The magnetic separator consists of an array of alternating and parallel capillary tubing and magnetizable wires, which is exposed to an applied magnetic field created by two parallel permanent magnets such that the magnetic field is perpendicular to both the wires and the fluid flow. In this paper, the performance of this separator was evaluated via preliminary in vitro flow experiments using a separator unit consisting of single capillary glass tubing and two metal wires. Pure water, ethylene glycol-water solution (v:v = 39:61 and v:v = 49:51) and human whole blood were used as the fluids. The results showed that when the viscosity increased from 1.0 cp to 3.0 cp, the capture efficiency (CE) decreased from 90% to 56%. However, it is still feasible to obtain >90% CE in blood flow if the separator design is optimized to create higher magnetic gradients and magnetic fields in the separation area.

Chen, Haitao; Kaminski, Michael D.; Caviness, Patricia L.; Xianqiao, Liu; Dhar, Promila; Torno, Michael; Rosengart, Axel J.

2007-02-01

75

Magnetic separation of micro-spheres from viscous biological fluids.  

SciTech Connect

A magnetically based detoxification system is being developed as a therapeutic tool for selective and rapid removal of biohazards, i.e. chemicals and radioactive substances, from human blood. One of the key components of this system is a portable magnetic separator capable of separating polymer-based magnetic nano/micro-spheres from arterial blood flow in an ex vivo unit. The magnetic separator consists of an array of alternating and parallel capillary tubing and magnetizable wires, which is exposed to an applied magnetic field created by two parallel permanent magnets such that the magnetic field is perpendicular to both the wires and the fluid flow. In this paper, the performance of this separator was evaluated via preliminary in vitro flow experiments using a separator unit consisting of single capillary glass tubing and two metal wires. Pure water, ethylene glycol-water solution (v:v = 39:61 and v:v = 49:51) and human whole blood were used as the fluids. The results showed that when the viscosity increased from 1.0 cp to 3.0 cp, the capture efficiency (CE) decreased from 90% to 56%. However, it is still feasible to obtain >90% CE in blood flow if the separator design is optimized to create higher magnetic gradients and magnetic fields in the separation area.

Chen, H.; Kaminski, M. D.; Xianqiao, L.; Caviness, P.; Torno, M.; Rosengart, A. J.; Dhar, P.; Chemical Engineering; Univ. of Chicago Pritzker School of Medicine; Illinois Inst. of Tech.

2007-02-21

76

Magnetically separable composite photocatalyst with enhanced photocatalytic activity.  

PubMed

A novel magnetically separable composite photocatalyst, anatase titania-coated magnetic activated carbon (TMAC), was prepared in this article. In the synthesis, magnetic activated carbon (MAC) was firstly obtained by adsorbing magnetic Fe3O4 nanoparticles onto the activated carbon (AC), and then the obtained MAC was directly coated by anatase titania nanoparticles prepared at low temperature (i.e. 75 degrees C). The prepared samples were characterized by XRD, SEM and vibrating sample magnetometer (VSM). The composite photocatalyst can be easily separated from solution by a magnet, its photocatalytic activity in degradation of phenol in aqueous solution also has dramatic enhancement compared to that of the neat titania. PMID:18406055

Ao, Yanhui; Xu, Jingjing; Shen, Xunwei; Fu, Degang; Yuan, Chunwei

2008-12-30

77

High Gradient Operation with the CEBAF Upgrade RF Control System  

SciTech Connect

The CEBAF Accelerator at Jefferson Lab is presently a 6 GeV five pass electron accelerator consisting of two superconducting linacs joined by independent magnetic transport arcs. Energy will be upgraded to 12 GeV with the addition of 10 new high gradient cryomodules (17+ MV/m). The higher gradients pose significant challenges beyond what the present analog low level RF (LLRF) control systems can handle reliably; therefore, a new LLRF control system is needed. A prototype system has been developed incorporating a large FPGA and using digital down and up conversion to minimize the need for analog components. The new system is more flexible and less susceptible to drifts and component nonlinearities. Because resonance control is critical to reach high gradients quickly, the new cryomodules will include a piezoelectric tuner for each cavity, and the LLRF controls must incorporate both feedback and feed-forward methods to achieve optimal resonance control performance. This paper discusses development of the new RF system, system performance for phase and amplitude stability and resonance control under Lorentz detuning measured during recent tests on a prototype cryomodule.

J. Hovater; G. Davis; Hai Dong; Alicia Hofler; Lawrence King; John Musson; Tomasz Plawski

2006-08-16

78

High Gradient Wakefields in Dielectric Loaded Structures  

SciTech Connect

Dielectric loaded wakefield structures have potential to be used as high gradient accelerator components. Using the high current drive beam at the Argonne Wakefield Accelerator Facility, we employed cylindrical dielectric loaded wakefield structures to generate accelerating fields of up to 86 MV/m, at 10 GHz. Short electron bunches of up to 86 nC are used to drive these fields, either as single bunches or as bunch trains. The structures consist of cylindrical ceramic tubes (cordierite) with a dielectric constant of 4.76, inserted into cylindrical copper waveguides. These standing-wave structures have a field probe near the outer diameter of the dielectric, in order to sample the RF fields generated by the electron bunches. Monitoring the field probe signal serves to verify the absence of electric breakdown in the structures. MAFIA simulations are used to calculate the amplitude of the fields generated by the traversing electrons bunches.

Conde, M. E.; Franchini, F.; Gai, W.; Konecny, R.; Liu, W.; Power, J. G.; Yusof, Z. [Argonne National Laboratory, 9700 South Cass Avenue, Argonne, IL 60439 (United States); Antipov, S.; Gao, F.; Wang, H. [Illinois Institute of Technology, 3300 South Federal Street, Chicago, IL 60616 (United States); Jing, C. [Euclid TechLabs, 5900 Harper Road, Solon, OH 44139 (United States)

2006-11-27

79

High gradient lens for charged particle beam  

DOEpatents

Methods and devices enable shaping of a charged particle beam. A dynamically adjustable electric lens includes a series of alternating a series of alternating layers of insulators and conductors with a hollow center. The series of alternating layers when stacked together form a high gradient insulator (HGI) tube to allow propagation of the charged particle beam through the hollow center of the HGI tube. A plurality of transmission lines are connected to a plurality of sections of the HGI tube, and one or more voltage sources are provided to supply an adjustable voltage value to each transmission line of the plurality of transmission lines. By changing the voltage values supplied to each section of the HGI tube, any desired electric field can be established across the HGI tube. This way various functionalities including focusing, defocusing, acceleration, deceleration, intensity modulation and others can be effectuated on a time varying basis.

Chen, Yu-Jiuan

2014-04-29

80

Velocity prediction in high-gradient channels  

NASA Astrophysics Data System (ADS)

SummaryIn 15 mountain stream reaches containing instream wood, we characterized velocity and flow resistance at bankfull through low flows. These data were: (1) used to assess the accuracy of previously published velocity prediction techniques for high-gradient channels; and (2) were combined with field data from other studies to develop general methodologies for predicting velocity and flow resistance in alluvial and mixed alluvial-bedrock channels both with and without step-forming instream wood. Velocity and flow resistance were poorly predicted by variables characterizing grain size and relative grain submergence. Conversely, methods based on detrended standard deviation of bed elevations (?z) and relative bedform submergence (h/?z) explained up to 84% of the variance in the measured flow resistance coefficients and 97% of the variance in dimensionless velocity. With an average velocity of 0.44 m/s for the collected measurements, velocity was predicted with RMS (root mean square) error as low as 0.071 m/s (16% of average) when discharge and bedform geometry is known and 0.10 m/s (23%) when only bedform geometry is known. Additionally, an empirical relationship indicates V/u?=h/?z, supporting previously-published laboratory findings using a field-based dataset in complex high-gradient channels. Interactions between instream wood and clasts result in substantially enhanced step heights and flow resistance. This compound effect defies description by grain size and relative grain submergence. However, ?z and h/?z quantify variability due to both clasts in combination with wood and clasts alone, providing relatively accurate predictions for the tested dataset and indicating substantial predictive capabilities in channels where bedforms are the primary source of flow resistance.

Yochum, Steven E.; Bledsoe, Brian P.; David, Gabrielle C. L.; Wohl, Ellen

2012-03-01

81

Magnetic-based microfluidic platform for biomolecular separation.  

PubMed

A novel microfluidic platform for manipulation of micro/nano magnetic particles was designed, fabricated and tested for applications dealing with biomolecular separation. Recently, magnetic immunomagnetic cell separation has attracted a noticeable attention due to the high selectivity of such separation methods. Strong magnetic field gradients can be developed along the entire wire, and the miniaturized size of these current-carrying conductors strongly enhances the magnetic field gradient and therefore produces large, tunable and localized magnetic forces that can be applied on magnetic particles and confine them in very small spots. Further increases in the values of the generated magnetic field gradients can be achieved by employing miniaturized ferromagnetic structures (pillars) which can be magnetized by an external magnetic field or by micro-coils on the same chip. In this study, we demonstrate magnetic beads trapping, concentration, transportation and sensing in a liquid sample under continuous flow by employing high magnetic field gradients generated by novel multi-functional magnetic micro-devices. Each individual magnetic micro-device consists of the following components: 1. Cu micro-coils array embedded in the silicon substrate with high aspect ratio conductors for efficient magnetic field generation 2. Magnetic pillar(s) made of the magnetic alloy NiCoP for magnetic field focusing and magnetic field gradient enhancement. Each pillar is magnetized by its corresponding coil 3. Integrated sensing coil for magnetic beads detection 4. Microfluidic chamber containing all the previous components. Magnetic fields of about 0.1 T and field gradients of around 300 T/cm have been achieved, which allowed to develop a magnetic force of 3 x 10(-9) N on a magnetic particle with radius of 1 mum. This force is large enough to trap/move this particle as the required force to affect such particles in a liquid sample is on the order of approximately pN. Trapping rates of up to 80% were achieved. Furthermore, different micro-coil designs were realized which allowed various movement modes and with different step-sizes. These results demonstrate that such devices incorporated within a microfluidic system can provide significantly improved spatial resolution and force magnitude for quick, efficient and highly selective magnetic trapping, separation and transportation, and as such they are an excellent solution for miniaturized mu-total analysis systems. PMID:16688574

Ramadan, Qasem; Samper, Victor; Poenar, Daniel; Yu, Chen

2006-06-01

82

Microstripes for transport and separation of magnetic particles  

PubMed Central

We present a simple technique for creating an on-chip magnetic particle conveyor based on exchange-biased permalloy microstripes. The particle transportation relies on an array of stripes with a spacing smaller than their width in conjunction with a periodic sequence of four different externally applied magnetic fields. We demonstrate the controlled transportation of a large population of particles over several millimeters of distance as well as the spatial separation of two populations of magnetic particles with different magnetophoretic mobilities. The technique can be used for the controlled selective manipulation and separation of magnetically labelled species. PMID:22655020

Donolato, Marco; Dalslet, Bjarke Thomas; Hansen, Mikkel Fougt

2012-01-01

83

Electron spin separation without magnetic field.  

PubMed

A nanodevice capable of separating spins of two electrons confined in a quantum dot formed in a gated semiconductor nanowire is proposed. Two electrons confined initially in a single quantum dot in the singlet state are transformed into the system of two electrons confined in two spatially separated quantum dots with opposite spins. In order to separate the electrons' spins we exploit transitions between the singlet and the triplet state, which are induced by resonantly oscillating Rashba spin-orbit coupling strength. The proposed device is all electrically controlled and the electron spin separation can be realized within tens of picoseconds. The results are supported by solving numerically the quasi-one-dimensional time-dependent Schroedinger equation for two electrons, where the electron-electron correlations are taken into account in the exact manner. PMID:25106038

Paw?owski, J; Szumniak, P; Skubis, A; Bednarek, S

2014-08-27

84

High-gradient, pulsed operation of superconducting niobium cavities  

SciTech Connect

Tests performed on several Niobium TM/sub 010/ cavities at frequencies of about 2856 MHz using a high-power, pulsed method indicate that, at the end of the charging pulse, peak surface magnetic fields of up to approx. 1300 Oe, corresponding to a peak surface electric field of approx. 68 MV/m, can be reached at 4.2/sup 0/K without appreciable average losses. Further studies of the properties of superconductors under pulsed operation might shed light on fundamental properties of rf superconductivity, as well as lead to the possibility of applying the pulse method to the operation of high-gradient linear colliders. 7 references, 30 figures, 2 tables.

Campisi, I.E.; Farkas, Z.D.

1984-02-01

85

Cell Separation Using Protein-A-Coated Magnetic Nanoclusters  

Microsoft Academic Search

A new immunomagnetic separation process that uses protein A-coated magnetic nanoclusters (PACMAN) as the separation vehicles has been developed. The nanoclusters are produced by sonicating egg yolk phosphatidylcholine and the transmembrane Fc receptor protein-A in a buffered aqueous ferrofluid suspension. The phospholipids appear to form a coating around clusters of 5-50 magnetic nanoparticles, while some of the protein-A associate with

Srinivas V. Sonti; Arijit Bose

1995-01-01

86

Quench performance and mechanical behavior of the first Fermilab-built prototype high gradient quadrupole for the LHC interaction regions  

Microsoft Academic Search

As part of the US LHC program to provide high gradient superconducting quadrupoles for the LHC interaction regions, a 5.5 meter long prototype magnet has been built and tested horizontally in a production type cryostat at Fermilab. This prototype magnet was used to validate the mechanical and magnetic design, production fabrication and assembly tooling. The first prototype magnet has met

N. Andreev; T. Arkan; P. Bauer; R. Bossert; J. Brandt; J. Carson; S. Caspi; D. R. Chichili; J. DiMarco; S. Feher; A. Ghosh; H. Glass; J. Kerby; M. J. Lamm; A. Makarov; A. D. McInturff; T. Nicol; A. Nobrega; I. Novitski; D. Orris; T. Peterson; R. Rabehl; W. Robotham; R. Scanlan; P. Schlabach; C. Sylvester; J. Strait; A. Tartaglia; J. C. Tompkins; G. Velev; S. Yadav; A. V. Zlobin

2002-01-01

87

Emerging magnetism and electronic phase separation at titanate interfaces  

NASA Astrophysics Data System (ADS)

The emergence of magnetism in otherwise nonmagnetic compounds and its underlying mechanisms have become the subject of intense research. Here we demonstrate that the nonmagnetic oxygen vacancies are responsible for an unconventional magnetic state common for titanate interfaces and surfaces. Using an effective multiorbital modeling, we find that the presence of localized vacancies leads to an interplay of ferromagnetic order in the itinerant t2g band and complex magnetic oscillations in the orbitally reconstructed eg band, which can be tuned by gate fields at oxide interfaces. The magnetic phase diagram includes highly fragmented regions of stable and phase-separated magnetic states forming beyond nonzero critical defect concentrations.

Pavlenko, N.; Kopp, T.; Mannhart, J.

2013-11-01

88

Apparatus and method for continuous separation of magnetic particles from non-magnetic fluids  

DOEpatents

A magnetic separator vessel (1) for separating magnetic particles from non-magnetic fluid includes a separation chamber having an interior and exterior wall, a top and bottom portion; a magnet (3) having first and second poles (2) positioned adjacent to the exterior wall, wherein the first pole is substantially diametrically opposed to the second pole; a inlet port (5) is directed into the top portion of the separation chamber, wherein the inlet port (5) is positioned adjacent to one of the first and second poles (2), wherein the inlet port (5) is adapted to transfer a mixture into the separation chamber; an underflow port (6) in communication with the bottom portion, wherein the underflow port (6) is adapted to receive the magnetic particles; and an overflow port (9) in communication with the separation chamber, wherein the overflow port (9) is adapted to receive the non-magnetic fluid.

Oder, Robin R. (Export, PA); Jamison, Russell E. (Lower Burrell, PA)

2010-02-09

89

Development of magnetic separation methods of analysis: magnetic field flow fractionation  

E-print Network

DEVELOPMENT OF MAGNETIC SEPARATION METHODS OF ANALYSIS: MAGNETIC FIELD FLOW FRACTIONATION A Thesis by JAIME GARCIA-RAMIREZ Submitted to the Graduate College of Texas A&M University in partial fulfillment of the requirement for the degree... of MASTER OF SCIENCE August 1980 Major Subject: Chemistry DEVELOPMENT OF MAGNETIC SEPARATION METHODS OF ANALYSIS: MAGNETIC FIELD FLOW FRACTIONATION A Thesis by JAIME GARCIA-RAMIREZ Approved as to style and content by: (Chairman of Committee) 1...

Garcia-Ramirez, Jaime

2012-06-07

90

High-gradient compact linear accelerator  

DOEpatents

A high-gradient linear accelerator comprises a solid-state stack in a vacuum of five sets of disc-shaped Blumlein modules each having a center hole through which particles are sequentially accelerated. Each Blumlein module is a sandwich of two outer conductive plates that bracket an inner conductive plate positioned between two dielectric plates with different thicknesses and dielectric constants. A third dielectric core in the shape of a hollow cylinder forms a casing down the series of center holes, and it has a dielectric constant different that the two dielectric plates that sandwich the inner conductive plate. In operation, all the inner conductive plates are charged to the same DC potential relative to the outer conductive plates. Next, all the inner conductive plates are simultaneously shorted to the outer conductive plates at the outer diameters. The signal short will propagate to the inner diameters at two different rates in each Blumlein module. A faster wave propagates quicker to the third dielectric core across the dielectric plates with the closer spacing and lower dielectric constant. When the faster wave reaches the inner extents of the outer and inner conductive plates, it reflects back outward and reverses the field in that segment of the dielectric core. All the field segments in the dielectric core are then in unipolar agreement until the slower wave finally propagates to the third dielectric core across the dielectric plates with the wider spacing and higher dielectric constant. During such unipolar agreement, particles in the core are accelerated with gradients that exceed twenty megavolts per meter. 10 figs.

Carder, B.M.

1998-05-26

91

High-gradient compact linear accelerator  

DOEpatents

A high-gradient linear accelerator comprises a solid-state stack in a vacuum of five sets of disc-shaped Blumlein modules each having a center hole through which particles are sequentially accelerated. Each Blumlein module is a sandwich of two outer conductive plates that bracket an inner conductive plate positioned between two dielectric plates with different thicknesses and dielectric constants. A third dielectric core in the shape of a hollow cylinder forms a casing down the series of center holes, and it has a dielectric constant different that the two dielectric plates that sandwich the inner conductive plate. In operation, all the inner conductive plates are charged to the same DC potential relative to the outer conductive plates. Next, all the inner conductive plates are simultaneously shorted to the outer conductive plates at the outer diameters. The signal short will propagate to the inner diameters at two different rates in each Blumlein module. A faster wave propagates quicker to the third dielectric core across the dielectric plates with the closer spacing and lower dielectric constant. When the faster wave reaches the inner extents of the outer and inner conductive plates, it reflects back outward and reverses the field in that segment of the dielectric core. All the field segments in the dielectric core are then in unipolar agreement until the slower wave finally propagates to the third dielectric core across the dielectric plates with the wider spacing and higher dielectric constant. During such unipolar agreement, particles in the core are accelerated with gradients that exceed twenty megavolts per meter.

Carder, Bruce M. (205 Rogue River Hwy., Gold Hill, OR 97525)

1998-01-01

92

Novel platform for minimizing cell loss on separation process: Droplet-based magnetically activated cell separator.  

PubMed

To reduce the problem of cell loss due to adhesion, one of the basic phenomena in microchannel, we proposed the droplet-based magnetically activated cell separator (DMACS). Based on the platform of the DMACS-which consists of permanent magnets, a coverslip with a circle-shaped boundary, and an injection tube-we could collect magnetically (CD45)-labeled (positive) cells with high purity and minimize cell loss due to adhesion. To compare separation efficiency between the MACS and the DMACS, the total number of cells before and after separation with both the separators was counted by flow cytometry. We could find that the number (3241/59 940) of cells lost in the DMACS is much less than that (22 360/59 940) in the MACS while the efficiency of cell separation in the DMACS (96.07%) is almost the same as that in the MACS (96.72%). Practically, with fluorescent images, it was visually confirmed that the statistical data are reliable. From the viability test by using Hoechst 33 342, it was also demonstrated that there was no cell damage on a gas-liquid interface. Conclusively, DMACS will be a powerful tool to separate rare cells and applicable as a separator, key component of lab-on-a-chip. PMID:17672779

Kim, Youngho; Hong, Su; Lee, Sang Ho; Lee, Kangsun; Yun, Seok; Kang, Yuri; Paek, Kyeong-Kap; Ju, Byeong-Kwon; Kim, Byungkyu

2007-07-01

93

Novel platform for minimizing cell loss on separation process: Droplet-based magnetically activated cell separator  

NASA Astrophysics Data System (ADS)

To reduce the problem of cell loss due to adhesion, one of the basic phenomena in microchannel, we proposed the droplet-based magnetically activated cell separator (DMACS). Based on the platform of the DMACS—which consists of permanent magnets, a coverslip with a circle-shaped boundary, and an injection tube—we could collect magnetically (CD45)-labeled (positive) cells with high purity and minimize cell loss due to adhesion. To compare separation efficiency between the MACS and the DMACS, the total number of cells before and after separation with both the separators was counted by flow cytometry. We could find that the number (3241/59940) of cells lost in the DMACS is much less than that (22360/59940) in the MACS while the efficiency of cell separation in the DMACS (96.07%) is almost the same as that in the MACS (96.72%). Practically, with fluorescent images, it was visually confirmed that the statistical data are reliable. From the viability test by using Hoechst 33 342, it was also demonstrated that there was no cell damage on a gas-liquid interface. Conclusively, DMACS will be a powerful tool to separate rare cells and applicable as a separator, key component of lab-on-a-chip.

Kim, Youngho; Hong, Su; Lee, Sang Ho; Lee, Kangsun; Yun, Seok; Kang, Yuri; Paek, Kyeong-Kap; Ju, Byeong-Kwon; Kim, Byungkyu

2007-07-01

94

Process to remove actinides from soil using magnetic separation  

DOEpatents

A process of separating actinide-containing components from an admixture including forming a slurry including actinide-containing components within an admixture, said slurry including a dispersion-promoting surfactant, adjusting the pH of the slurry to within a desired range, and, passing said slurry through a pretreated matrix material, said matrix material adapted to generate high magnetic field gradients upon the application of a strong magnetic field exceeding about 0.1 Tesla whereupon a portion of said actinide-containing components are separated from said slurry and remain adhered upon said matrix material is provided.

Avens, Larry R. (Los Alamos, NM); Hill, Dallas D. (Los Alamos, NM); Prenger, F. Coyne (Los Alamos, NM); Stewart, Walter F. (Las Cruces, NM); Tolt, Thomas L. (Los Alamos, NM); Worl, Laura A. (Los Alamos, NM)

1996-01-01

95

Separation of feeble magnetic particles with magneto-Archimedes levitation  

Microsoft Academic Search

Particles and solid substances with feeble magnetic susceptibility were levitated by magnetic fields with the aid of the “magneto-Archimedes levitation” method [Nature 393 (1998) 749]. A novel feature was found, namely that the initial particle mixture levitated underwent separation into each kind of the ingredient particle aggregates. The samples levitated were NaCl–KCl grain mixtures, and colored glass particles. The experiments

Y Ikezoe; T Kaihatsu; S Sakae; H Uetake; N Hirota; K Kitazawa

2002-01-01

96

Differential magnetic catch and release: Separation, purification, and characterization of magnetic nanoparticles and particle assemblies  

NASA Astrophysics Data System (ADS)

Magnetic nanoparticles uniquely combine superparamagnetic behavior with dimensions that are smaller than or the same size as molecular analytes. The integration of magnetic nanoparticles with analytical methods has opened new avenues for sensing, purification, and quantitative analysis. Applied magnetic fields can be used to control the motion and properties of magnetic nanoparticles; in analytical chemistry, use of magnetic fields provides methods for manipulating and analyzing species at the molecular level. The ability to use applied magnetic fields to control the motion and properties of magnetic nanoparticles is a tool for manipulating and analyzing species at the molecular level, and has led to applications including analyte handing, chemical sensors, and imaging techniques. This is clearly an area where significant growth and impact in separation science and analysis is expected in the future. In Chapter 1, we describe applications of magnetic nanoparticles to analyte handling, chemical sensors, and imaging techniques. Chapter 2 reports the purification and separation of magnetic nanoparticle mixtures using the technique developed in our lab called differential magnetic catch and release (DMCR). This method applies a variable magnetic flux orthogonal to the flow direction in an open tubular capillary to trap and controllably release magnetic nanoparticles. Magnetic moments of 8, 12, and 17 nm diameter CoFe2O4 nanoparticles are calculated using the applied magnetic flux density and experimentally determined force required to trap 50% of the particle sample. Balancing the relative strengths of the drag and magnetic forces enable separation and purification of magnetic CoFe2 O4 nanoparticle samples with < 20 nm diameters. Samples were characterized by transmission electron microscopy to determine the average size and size dispersity of the sample population. DMCR is further demonstrated to be useful for separation of a magnetic nanoparticle mixture, resulting in samples with narrowed size distributions. Differential magnetic catch and release has been used as a method for the purification and separation of magnetic nanoparticles. In Chapter 3 the separation metrics are reported. DMCR separates nanoparticles in the mobile phase by magnetic trapping of magnetic nanoparticles against the wall of an open tubular capillary wrapped between two narrowly spaced electromagnetic poles. Using Au and CoFe2O4 nanoparticles as model systems, the loading capacity of the 250 microm diameter capillary is determined to be ˜130 microg, and is scalable to higher quantities with larger bore capillary. Peak resolution in DMCR is externally controlled by selection of the release time (Rt) at which the magnetic flux density is removed, however longer capture times are shown to reduce the capture yield. In addition, the magnetic nanoparticle capture yields are observed to depend on the nanoparticle diameter, mobile phase viscosity and velocity, and applied magnetic flux. Using these optimized parameters, three samples of CoFe 2O4 nanoparticles whose diameters are different by less than 10 nm are separated with excellent resolution and capture yield, demonstrating the capability of DMCR for separation and purification of magnetic nanoparticles. Individual hybrid nanocrystals possess multiple structural units with solid state interfaces, giving them a wide range of possible applications. Synthesis of truly monodisperse nanoparticles and hybrid nanocrystals is a formidable task, which has led us to apply our analytical technique, differential magnetic catch and release, to separate and purify magnetic nanoparticles. Using an open tubular capillary column and electromagnet, DMCR separates magnetic nanoparticles based on a balance of their magnetic moment and hydrodynamic size. Chapter 4 focuses on the purification of real world samples of hybrid nanocrystals including Au-Fe3O4 heterostructures and FePt-Fe3O4 dimers. Samples are characterized with transmission electron microscopy, UV-Vis, X-ray diffraction spectroscopy, selected area electro

Beveridge, Jacob S.

97

Rapid and continuous magnetic separation in droplet microfluidic devices.  

PubMed

We present a droplet microfluidic method to extract molecules of interest from a droplet in a rapid and continuous fashion. We accomplish this by first marginalizing functionalized super-paramagnetic beads within the droplet using a magnetic field, and then splitting the droplet into one droplet containing the majority of magnetic beads and one droplet containing the minority fraction. We quantitatively analysed the factors which affect the efficiency of marginalization and droplet splitting to optimize the enrichment of magnetic beads. We first characterized the interplay between the droplet velocity and the strength of the magnetic field and its effect on marginalization. We found that marginalization is optimal at the midline of the magnet and that marginalization is a good predictor of bead enrichment through splitting at low to moderate droplet velocities. Finally, we focused our efforts on manipulating the splitting profile to improve the enrichment provided by asymmetric splitting. We designed asymmetric splitting forks that employ capillary effects to preferentially extract the bead-rich regions of the droplets. Our strategy represents a framework to optimize magnetic bead enrichment methods tailored to the requirements of specific droplet-based applications. We anticipate that our separation technology is well suited for applications in single-cell genomics and proteomics. In particular, our method could be used to separate mRNA bound to poly-dT functionalized magnetic microparticles from single cell lysates to prepare single-cell cDNA libraries. PMID:25501881

Brouzes, Eric; Kruse, Travis; Kimmerling, Robert; Strey, Helmut H

2015-01-22

98

Pair separation of magnetic elements in the quiet Sun  

NASA Astrophysics Data System (ADS)

The dynamic properties of the quiet Sun photosphere can be investigated by analyzing the pair dispersion of small-scale magnetic fields (i.e., magnetic elements). By using 25 h-long Hinode magnetograms at high spatial resolution (0.3 arcsec), we tracked 68 490 magnetic element pairs within a supergranular cell near the disk center. The computed pair separation spectrum, calculated on the whole set of particle pairs independently of their initial separation, points out what is known as a super-diffusive regime with spectral index ? = 1.55 ± 0.05, in agreement with the most recent literature, but extended to unprecedented spatial and temporal scales (from granular to supergranular). Furthermore, for the first time, we investigated here the spectrum of the mean square displacement of pairs of magnetic elements, depending on their initial separation r0. We found that there is a typical initial distance above (below) which the pair separation is faster (slower) than the average. A possible physical interpretation of such a typical spatial scale is also provided.

Giannattasio, F.; Berrilli, F.; Biferale, L.; Del Moro, D.; Sbragaglia, M.; Bellot Rubio, L.; Goši?, M.; Orozco Suárez, D.

2014-09-01

99

Magnetic separation as a plutonium residue enrichment process  

SciTech Connect

We have subjected several plutonium contaminated residues to Open Gradient Magnetic Separation (OGMS) on an experimental scale. Separation of graphite, bomb reduction sand, and bomb reduction sand, and bomb reduction sand, slag, and crucible, resulted in a plutonium rich fraction and a plutonium lean fraction. The lean fraction varied between about 20% to 85% of the feed bulk. The plutonium content of the lean fraction can be reduced from about 2% in the feed to the 0.1% to 0.5% range dependent on the portion of the feed rejected to this lean fraction. These values are low enough in plutonium to meet economic discard limits and be considered for direct discard. Magnetic separation of direct oxide reduction and electrorefining pyrochemical salts gave less favorable results. While a fraction very rich in plutonium could be obtained, the plutonium content of the lean fraction was to high for direct discard. This may still have chemical processing applications. OGMS experiments at low magnetic field strength on incinerator ash did give two fractions but the plutonium content of each fraction was essentially identical. Thus, no chemical processing advantage was identified for magnetic separation of this residue. The detailed results of these experiments and the implications for OGMS use in recycle plutonium processing are discussed. 4 refs., 3 figs., 9 tabs.

Avens, L.R.; McFarlan, J.T.; Gallegos, U.F.

1989-01-01

100

Coil geometry for efficient active compensation with separated magnetic shields  

NASA Astrophysics Data System (ADS)

We have already proposed a new method of magnetic shielding aiming for magnetocardiography, in which magnetic shells are separated and a new compensation scheme is employed to allow for wide space between them. Each magnetic shell that consists of a half of the cylinder (diameter=20 cm and length=60 cm) and two flanges at both ends of the half cylinder extending along the radial direction has a saddle coil on its outer surface with the coil's long straight section running parallel to the axis of the cylinder. In this paper, the relationship between the width of the long straight sections of the saddle coil and the efficiency of the active compensation is investigated by the finite element method (FEM) analysis and by experiments. A magnetic shield used in this study is a double shell structure where each shell is made of stacked amorphous tapes and the outer shell has a magnetic shaking coil for the enhancement of the permeability. We have found that for a given magnetic field, the compensation current necessary for a given magnetic field varies by a factor of 3 depending on the width of a saddle coil and that its value monotonically decreases with increasing the width. We have also confirmed that the phase delay of the compensation magnetic field experienced while it comes in the magnetic shell is small.

Nakashima, Yoshihiro; Sasada, Ichiro

2009-04-01

101

Magnetic Separations with Magnetite: Theory, Operation, and Limitations  

SciTech Connect

This dissertation documents the theory development and experimental plan followed to describe how a magnetite-based column under the influence of an external magnetic field functions as a magnetic separator. Theoretical simulations predict that weekly paramagnetic particles in the sub-micron range can be magnetically separated while diamagnetic particles as large as 2 microns in diameter may pass. Magnetite-based columns were evaluated as magnetically-controllable enhanced filtration devices. There was no evidence of enhanced filtration for diamagnetic particles by the magnetite-based bed. Magnetite-based magnetic separators have proven to be effective in specific laboratory experiments, indicating a potential feasibility for scale-up operations. Column media-filter type filtration effects indicate a magnetite-based column would not be suitable for treatment of a waste stream with a high diamagnetic solids content or high volume throughput requirements. Specific applications requiring removal of sub-micron para- or ferromagnetic particles under batch or Stokes flow conditions would be most applicable.

G. B. Cotten

2000-08-01

102

Experimental investigation of magnetically actuated separation using tangential microfluidic channels and magnetic nanoparticles.  

PubMed

A novel continuous switching/separation scheme of magnetic nanoparticles (MNPs) in a sub-microlitre fluid volume surrounded by neodymium permanent magnet is studied in this work using tangential microfluidic channels. Polydimethylsiloxane tangential microchannels are fabricated using a novel micromoulding technique that can be done without a clean room and at much lower cost and time. Negligible switching of MNPs is seen in the absence of magnetic field, whereas 90% of switching is observed in the presence of magnetic field. The flow rate of MNPs solution had dramatic impact on separation performance. An optimum value of the flow rate is found that resulted in providing effective MNP separation at much faster rate. Separation performance is also investigated for a mixture containing non-magnetic polystyrene particles and MNPs. It is found that MNPs preferentially moved from lower microchannel to upper microchannel resulting in efficient separation. The proof-of-concept experiments performed in this work demonstrates that microfluidic bioseparation can be efficiently achieved using functionalised MNPs, together with tangential microchannels, appropriate magnetic field strength and optimum flow rates. This work verifies that a simple low-cost magnetic switching scheme can be potentially of great utility for the separation and detection of biomolecules in microfluidic lab-on-a-chip systems. PMID:25014081

Munir, Ahsan; Zhu, Zanzan; Wang, Jianlong; Zhou, Hong Susan

2014-06-01

103

Magnetic nano-sorbents for fast separation of radioactive waste  

SciTech Connect

In order to find a cost effective and environmentally benign technology to treat the liquid radioactive waste into a safe and stable form for resource recycling or ultimate disposal, this study investigates the separation of radioactive elements from aqueous systems using magnetic nano-sorbents. Our current study focuses on novel magnetic nano-sorbents by attaching DTPA molecules onto the surface of double coated magnetic nanoparticles (dMNPs), and performed preliminary sorption tests using heavy metal ions as surrogates for radionuclides. The results showed that the sorption of cadmium (Cd) and lead (Pb) onto the dMNP-DTPA conjugates was fast, the equilibrium was reached in 30 min. The calculated sorption capacities were 8.06 mg/g for Cd and 12.09 mg/g for Pb. After sorption, the complex of heavy elements captured by nano-sorbents can be easily manipulated and separated from solution in less than 1 min by applying a small external magnetic field. In addition, the sorption results demonstrate that dMNP-DTPA conjugates have a very strong chelating power in highly diluted Cd and Pb solutions (1-10 ?g/L). Therefore, as a simple, fast, and compact process, this separation method has a great potential in the treatment of high level waste with low concentration of transuranic elements compared to tradition nuclear waste treatment. (authors)

Zhang, Huijin [Environmental Science Program, University of Idaho, Moscow, ID 83844 (United States); Kaur, Maninder [Department of Physics, University of Idaho, Moscow, ID 83844 (United States); Qiang, You [Environmental Science Program, University of Idaho, Moscow, ID 83844 (United States); Department of Physics, University of Idaho, Moscow, ID 83844 (United States)

2013-07-01

104

Development of micro immuno-magnetic cell sorting system with lamination mixer and magnetic separator  

E-print Network

at the inlet, turned over, and merged at the outlet to form a laminated layer. For n number of mixer units of a serpentine separation channel and embedded magnetic coils along the channel. Two layers of fluids are introduced at the inlet of the separation channel. The lower layer is the cell mixture, and the upper layer

Kasagi, Nobuhide

105

Separation of variables and the XXZ Gaudin magnet  

E-print Network

In this work we generalise previous results connecting (rational) Gaudin magnet models and classical separation of variables. It is shown that the connection persists for the case of linear r-matrix algebra which corresponds to the trigonometric 4x4 r-matrix (of the XXZ type). We comment also on the corresponding problem for the elliptic (XYZ) r-matrix. A prescription for obtaining integrable systems associated with multiple poles of an L-operator is given.

E. G. Kalnins; V. B. Kuznetsov; Willard Miller, Jr

1994-12-21

106

Kinetic approach for the purification of nucleotides with magnetic separation.  

PubMed

The isolation of ?-nicotinamide adenine dinucleotide is of great importance since it is widely used in different scientific and technologic fields such as biofuel cells, sensor technology, and hydrogen production. In order to isolate ?-nicotinamide adenine dinucleotide, first 3-aminophenyboronic acid functionalized magnetic nanoparticles were prepared to serve as a magnetic solid support and subsequently they were used for reversible adsorption/desorption of ?-nicotinamide adenine dinucleotide in a batch fashion. The loading capacity of the 3-aminophenyboronic acid functionalized nanoparticles for ?-nicotinamide adenine dinucleotide adsorption was 13.0 ?mol/g. Adsorption kinetic and isotherm studies showed that the adsorption process followed a pseudo-second-order kinetic model and the experimental data can be represented using Langmuir isotherm model. The 3-aminophenyboronic acid functionalized magnetic nanoparticles were proposed as an alternative support for the ?-nicotinamide adenine dinucleotide purification. The results elucidated the significance of magnetic separation as a fast, relatively simple, and low-cost technique. Furthermore, the magnetic supports can be reused at least five times for purification processes. PMID:25199632

Tural, Servet; Tural, Bilsen; Ece, Mehmet ?akir; Yetkin, Evren; Özkan, Necati

2014-11-01

107

Experimental and theoretical investigation of high gradient acceleration  

SciTech Connect

This report contains a technical progress summary of the research conducted under the auspices of DOE Grant No. DE-FG0291ER-40648. Experimental and Theoretical Investigations of High Gradient Acceleration.'' This grant supports three research tasks: Task A consists of the design and fabrication of a 17GHz of photocathode gun, Task B supports the testing of high gradient acceleration using a 33GHz structure, and Task C comprises theoretical investigations, both in support of the experimental tasks and on critical physics issues for the development of high energy linear colliders. This report is organized as follows. The development of an rf gun design and research progress on the picosecond laser system is summarized in Sec. 2, the status of the studies of the LBL/Haimson high gradient structure, using a 50 MW free-electron laser is summarized in Sec. 3, and theoretical research progress is described in Sec. 4. Supporting material is contained in Appendices A-G.

Bekefi, G.; Chen, C.; Chen, S.; Danly, B.; Temkin, R.J.; Wurtele, J.S.

1992-02-01

108

Open-gradient Magnetic Separator With Racetrack Coils Suitable for Cleaning Aqueous Solutions  

Microsoft Academic Search

Superconductivity enables magnetic fields in a magnitude of 5-10 times greater than conventional electromagnets. Applied to magnetic separation, use of superconducting magnets opens the possibility to separate sub-micron sized paramagnetic particles. Open-gradient magnetic separation (OGMS) enables continuous operation without the need of matrix-elements. Such a separator consisting of liquid helium cryostat and an Nb3Sn coils were designed and constructed for

Teemu Hartikainen; Risto Mikkonen

2006-01-01

109

Apparatus for magnetic separation of paramagnetic and diamagnetic material  

DOEpatents

The present invention relates to methods and apparatus for segregating paramagnetic from diamagnetic particles in particulate material and, in particular, to the open gradient magnetic separation of ash producing components and pyritic sulfur from coal. The apparatus includes a vertical cylinder and a rotatable vertical screw positioned within the cylinder, the screw having a helical blade angled downwardly and outwardly from the axis. Rotation of the vertical screw causes denser particles, which in the case of coal include pyritic sulfur and ash, which are paramagnetic, to migrate to the outside of the screw, and less dense particles, such as the low sulfur organic portion of the coal, which are diamagnetic, to migrate towards the center of the screw. A vibration mechanism attached to the screw causes the screw to vibrate during rotation, agitating and thereby accommodating further segregation of the particles. An open gradient magnetic field is applied circumferentially along the entire length of the screw by a superconducting quadrupole magnet. The open gradient magnetic field further segregates the paramagnetic particles from the diamagnetic particles. The paramagnetic particles may then be directed from the cylinder into a first storage bin, and the diamagnetic particles, which are suitable for relatively clean combustion, may be directed into a second storage bin. 5 figs.

Doctor, R.D.

1988-10-18

110

Apparatus for magnetic separation of paramagnetic and diamagnetic material  

DOEpatents

The present invention relates to methods and apparatus for segregating paramagnetic from diamagnetic particles in particulate material and, in particular, to the open gradient magnetic separation of ash producing components and pyritic sulfur from coal. The apparatus includes a vertical cylinder and a rotatable vertical screw positioned within the cylinder, the screw having a helical blade angled downwardly and outwardly from the axis. Rotation of the vertical screw causes denser particles, which in the case of coal include pyritic sulfur and ash, which are paramagnetic, to migrate to the outside of the screw, and less dense particles, such as the low sulfur organic portion of the coal, which are diamagnetic, to migrate towards the center of the screw. A vibration mechanism attached to the screw causes the screw to vibrate during rotation, agitating and thereby accommodating further segregation of the particles. An open gradient magnetic field is applied circumferentially along the entire length of the screw by a superconducting quadrupole magnet. The open gradient magnetic field further segregates the paramagnetic-particles from the diamagnetic particles. The paramagnetic particles may then be directed from the cylinder into a first storage bin, and the diamagnetic particles, which are suitable for relatively clean combustion, may be directed into a second storage bin. 5 figs.

Doctor, R.D.

1986-07-24

111

Apparatus for magnetic separation of paramagnetic and diamagnetic material  

DOEpatents

The present invention relates to methods and apparatus for segregating paramagnetic from diamagnetic particles in particulate material and, in particular, to the open gradient magnetic separation of ash producing components and pyritic sulfur from coal. The apparatus includes a vertical cylinder and a rotatable vertical screw positioned within the cylinder, the screw having a helical blade angled downwardly and outwardly from the axis. Rotation of the vertical screw causes denser particles, which in the case of coal include pyritic sulfur and ash, which are paramagnetic, to migrate to the outside of the screw, and less dense particles, such as the low sulfur organic portion of the coal, which are diamagnetic, to migrate towards the center of the screw. A vibration mechanism attached to the screw causes the screw to vibrate during rotation, agitating and thereby accommodating further segregation of the particles. An open gradient magnetic field is applied circumferentially along the entire length of the screw by a superconducting quadropole magnet. The open gradient magnetic field further segregates the paramagnetic particles from the diamagnetic particles. The paramagnetic particles may then be directed from the cylinder into a first storage bin, and the diamagnetic particles, which are suitable for relatively clean combustion, may be directed into a second storage bin.

Doctor, Richard D. (Glen Ellyn, IL)

1988-01-01

112

High gradient acceleration in a 17 GHz photocathode RF gun  

Microsoft Academic Search

The physics and technological issues involved in high gradient particle acceleration at high microwave (RF) frequencies are under study at MIT. The 17 GHz photocathode RF gun has a 1½ cell room temperature copper cavity with a peak accelerating gradient of about 250 MV\\/m. The anticipated beam parameters, when operating with a photoemission cathode, are: energy 2 MeV, normalized emittance

S. C. Chen; J. Gonichon; L. C.-L. Lin; R. J. Temkin; S. Trotz; B. G. Danly; J. S. Wurtele

1993-01-01

113

High Energy Accelerating Structures for High Gradient Proton Linac Applications  

Microsoft Academic Search

The high-energy part of a proton linac, following a drift tube section, accelerates protons and H- ions of energies above 150 MeV. High efficiency and high gradients in the accelerating structure considered for this part of a proton linac are the objectives of this study. Several known and improved structures working at 1350 MHz were optimized for maximum shunt impedance.

J. J. Manca; E. A. Knapp; D. A. Swenson

1977-01-01

114

On-chip Magnetic Separation and Cell Encapsulation in Droplets†  

PubMed Central

The demand for high-throughput single cell assays is gaining importance because of the heterogeneity of many cell suspensions, even after significant initial sorting. These suspensions may display cell-to-cell variability at the gene expression level that could impact single cell functional genomics, cancer, stem-cell research and drug screening. The on-chip monitoring of individual cells in an isolated environment would prevent cross-contamination, provide high recovery yield, and enable study of biological traits at a single cell level. These advantages of on-chip biological experiments is a significant improvement for myriad of cell analyses over conventional methods, which require bulk samples providing only averaged information on cell metabolism. We report on a device that integrates mobile magnetic trap array with microfluidic technology to provide, combined functionality of separation of immunomagnetically labeled cells or magnetic beads and their encapsulation with reagents into pico-liter droplets. This scheme of simultaneous reagent delivery and compartmentalization of the cells immediately after sorting, all performed seamlessly within the same chip, offers unique advantages such as the ability to capture cell traits as originated from its native environment, reduced chance of contamination, minimal use and freshness of the reagent solution that reacts only with separated objects, and tunable encapsulation characteristics independent of the input flow. In addition to the demonstrated preliminary cell viability assay, the device can potentially be integrated with other up- or downstream on-chip modules to become a powerful single-cell analysis tool. PMID:23370785

Chen, Aaron; Byvank, Tom; Chang, Woo-Jin; Bharde, Atul; Vieira, Greg; Miller, Brandon; Chalmers, Jeffrey J.; Bashir, Rashid; Sooryakumar, Ratnasingham

2014-01-01

115

On-chip Magnetic Separation and Cell Encapsulation in Droplets  

NASA Astrophysics Data System (ADS)

The demand for high-throughput single cell assays is gaining importance because of the heterogeneity of many cell suspensions, even after significant initial sorting. These suspensions may display cell-to-cell variability at the gene expression level that could impact single cell functional genomics, cancer, stem-cell research and drug screening. The on-chip monitoring of individual cells in an isolated environment could prevent cross-contamination, provide high recovery yield and ability to study biological traits at a single cell level These advantages of on-chip biological experiments contrast to conventional methods, which require bulk samples that provide only averaged information on cell metabolism. We report on a device that integrates microfluidic technology with a magnetic tweezers array to combine the functionality of separation and encapsulation of objects such as immunomagnetically labeled cells or magnetic beads into pico-liter droplets on the same chip. The ability to control the separation throughput that is independent of the hydrodynamic droplet generation rate allows the encapsulation efficiency to be optimized. The device can potentially be integrated with on-chip labeling and/or bio-detection to become a powerful single-cell analysis device.

Chen, A.; Byvank, T.; Bharde, A.; Miller, B. L.; Chalmers, J. J.; Sooryakumar, R.; Chang, W.-J.; Bashir, R.

2012-02-01

116

Primary beneficiation of tantalite using magnetic separation and acid leaching  

NASA Astrophysics Data System (ADS)

Primary beneficiation was successfully performed prior to dissolution of manganotantalite (sample A) and ferrotantalite (sample C) samples obtained from two different mines in the Naquissupa area, Mozambique. Magnetic separation removed the majority of iron and titanium, whereas H2SO4 leaching removed a large portion of thorium and uranium in these samples. Analytical results indicated that 64.14wt% and 72.04wt% of the total Fe and Ti, respectively, and ˜2wt% each of Nb2O5 and Ta2O5 were removed from sample C (ferrotantalite) using the magnetic separation method, whereas only 9.64wt% and 8.66wt% of total Fe2O3 and TiO2, respectively, and ˜2wt% each of Nb2O5 and Ta2O5 were removed from sample A (manganotantalite). A temperature of 50°C and a leaching time of 3 h in the presence of concentrated H2SO4 were observed to be the most appropriate leaching conditions for removal of radioactive elements from the tantalite ores. The results obtained for sample A under these conditions indicated that 64.14wt% U3O8 and 60.77wt% ThO2 were leached into the acidic solution, along with 4.45wt% and 0.99wt% of Nb2O5 and Ta2O5, respectively.

Nete, M.; Koko, F.; Theron, T.; Purcell, W.; Nel, J. T.

2014-12-01

117

Hybrid magnetic field gradient, rotating wall device for enhanced colloidal magnetic affinity separations  

NASA Astrophysics Data System (ADS)

A 2.0 cm internal diameter 1 m long, axially-rotating horizontal glass tube, with four axially located repeating hybrid magnetic units, is used as part of a flow-through, colloidal magnetic affinity separation device. Each magnetic unit consists of an alternating current solenoid surrounding the chamber followed by four azimuthally distributed permanent magnets that rotate with the chamber. The separation is demonstrated on a model feed system consisting of a mixture of 1.0 ?m diameter biotinylated latex beads (targets) and 9.7 ?m diameter non-functionalized latex beads (non-targets) at a 1:1 number ratio. Two feed flow rates of 12 ml/min and 35 ml/min were used until a total of 600 ml of sample were processed for each. At the low rate we achieved capture efficiency 60%, a separation factor of 18.2 with 95% purity. For the higher flow rate, the capture efficiency was 40%, the separation factor 18.6 with 87% purity. The same device also was used for removal of cadmium ions from a cadmium sulfate solution. Two arrangements for the magnetic units were used. In the first configuration, four hybrid pairs were distributed axially-each pair consisted of an alternating current carrying solenoid, followed by four azimuthally distributed permanent magnets that rotate with the chamber. In the second configuration, all four solenoids were placed first, followed by the four sets of four azimuthally distributed permanent magnets. 1-10 ?m diameter magnetic particles with iron oxide nanoparticles embedded within a quaternary ammonium cellulose matrix (MagaCell- Q, Cortex Biochem) at a starting concentration of 0.5 mg particles/mL were used as the mobile solid support. The feed consisted of a 10.0 mg/L cadmium sulfate solution, at a flow rate of 35 mL/min. For the arrangement, the cadmium concentration at the exit of the third stage dropped to 0.97 mg/L. The second configuration produced a final cadmium concentration of 0.68 mg/L. For the first arrangement, three stage processing resulted in an overall ~90% w/w cadmium removal, and the second configuration removed ~94% of the original cadmium ions. The operating mode of this device requires a periodic interruption of the feed flow, leading to down time. Thus there is a compelling motivation to the development of the continuous device. The continuous, hybrid magnetic field gradient separation device, designed in our lab, incorporates a 1.0 cm internal diameter 1m long, axially-rotating horizontal glass tube, with four axially located repeating magnetic units. Each magnetic unit consists of an alternating current solenoid surrounding the chamber followed by electromagnets at a distance of 4.0 cm from the end of the solenoid. A computer controlled DC current flowing in the electromagnet is used to generate radial magnetic field gradients within the tube, allowing magnetic particles to be drawn to the walls. MagaCell-Q magnetic particles were used to demonstrate the removal of cadmium ions from an aqueous solution. Three stage processing resulted in an overall ~92% cadmium removal. Thus, this breakthrough technology in continuous separation can lead to a large increase in processing volume and reduced down time compared to the flow-through device, without loss of removal efficiency. While the specific system studied here consists of removal of cadmium ions from an aqueous solution, the general principle of magnetic colloidal separation using the flow-through and continuous devices can be exploited for other environmental and biotechnological applications where large volumes of sample must be processed with high efficiency.

Ghebremeskel, Alazar Negusse

118

Magnetic and fluorescence-encoded polystyrene microparticles for cell separation  

NASA Astrophysics Data System (ADS)

Materials assisting with the efforts of cell isolation are attractive for numerous biomedical applications including tissue engineering and cell therapy. Here, we have developed surface modification methods on microparticles for the purposes of advanced cell separation. Iron oxide nanoparticles were incorporated into 200 ?m polystyrene microparticles for separation of particle-bound cells from non-bound cells in suspension by means of a permanent magnet. The polystyrene microparticles were further encoded with fluorescent quantum dots (QD) as identification tags to distinguish between specific microparticles in a mixture. Cluster of differentiation (CD) antibodies were displayed on the surface of the microparticles through direct adsorption and various methods of covalent attachment. In addition, a protein A coating was used to orientate the antibodies on the microparticle surface and to maximise accessibility of the antigen-binding sites. Microparticles which carried CD antibodies via covalent attachment showed greater cell attachment over those modifications that were only adsorbed to the surface through weak electrostatic interactions. Greatest extent of cell attachment was observed on microparticles modified with protein A - CD antibody conjugates. B and T lymphocytes were successfully isolated from a mixed population using two types of microparticles displaying B and T cell specific CD antibodies, respectively. Our approach will find application in preparative cell separation from tissue isolates and for microcarrier-based cell expansion.

Bradbury, Diana; Anglin, Emily J.; Bailey, Sheree; Macardle, Peter J.; Fenech, Michael; Thissen, Helmut; Voelcker, Nicolas H.

2008-12-01

119

Study on magnetic separation for decontamination of cesium contaminated soil by using superconducting magnet  

NASA Astrophysics Data System (ADS)

The accident of Fukushima Daiichi nuclear power plant caused the diffusion of radioactive cesium over the wide area. We examined the possibility of applying magnetic separation method using the superconducting magnet, which can process a large amount of the soil in high speed, to the soil decontamination and volume reduction of the radioactive cesium contaminated soil. Clay minerals are classified as 2:1 and 1:1 types by the difference of their layer structures, and these types of minerals are respectively paramagnetic and diamagnetic including some exception. It is known that most of the radioactive cesium is strongly adsorbed on the clay, especially on 2:1 type clay minerals. It is expected that the method which can separate only 2:1 type clay minerals selectively from the mixture clay minerals can enormously contribute to the volume reduction of the contaminated soil. In this study, the components in the clay before and after separation were evaluated to estimate the magnetic separation efficiency by using X-ray diffraction. From the results, the decontamination efficiency and the volume reduction ratio were estimated in order to examine the appropriate separation conditions for the practical decontamination of the soil.

Igarashi, Susumu; Nomura, Naoki; Mishima, Fumihito; Akiyama, Yoko

2014-09-01

120

Magnetic Separation and Magnetic Properties of Low-Grade Manganese Carbonate Ore  

NASA Astrophysics Data System (ADS)

The relation between the magnetic separation behavior and magnetic properties of a low-grade manganese ore was analyzed before and after treatment by direct reduction with coal. It was found that raw ore with an initial average grade of 10.39% Mn and consisting of diamagnetic and paramagnetic minerals can be concentrated by high-intensity magnetic separation to produce a salable product with a grade of 22.75% Mn and a recovery of 89.88%. In contrast, direct reduction of the ore results in a new Mn-Fe oxide phase formed with a combination of ferromagnetic and paramagnetic properties, thereby increasing the magnetic susceptibilities of the ore by almost two orders of magnitude. The grade of Mn for the roasted ore could only be concentrated to 15.49% with a recovery of 66.67%. Therefore, it is concluded that the low-grade manganese ores with antiferromagnetic and paramagnetic (or diamagnetic, but not strongly ferromagnetic) properties could be efficiently beneficiated via high-intensity magnetic separation.

Wu, Y.; Shi, B.; Ge, W.; Yan, C. J.; Yang, X.

2014-11-01

121

The Development of the Separation Apparatus of Phosphor by Controlling the Magnetic Force  

NASA Astrophysics Data System (ADS)

The phosphor wastes contain the multiple kinds of rare-earth phosphors with high market value. Because of increasing demand for rare-earth, the technique to recover and reuse the rare-earth in the phosphor wastes is required. In this study, we focused on the difference of physical property such as magnetic susceptibility and density for each type of phosphor and tried to separate and recover the phosphors by using the magnetic separation technique utilizing the difference of the traction force to the magnet acting on the particles. Magneto-Archimedes method is method separation technique utilizi g the difference of magnetic susceptibility and density. We developed the magnetic separation apparatus by applying this technique. To develop the practical separation apparatus, the continuous process is required. Hence the fundamental experiment utilizing High Temperature Superconducting (HTS) Bulk Magnet which can generate the strong magnetic force was conducted. As a result, we succeeded the continuous separation of the phosphor wastes.

Wada, K.; Mishima, F.; Akiyama, Y.; Nishijima, S.

122

Experimental and theoretical investigation of high gradient acceleration  

SciTech Connect

This report contains a technical progress summary of the research conducted under the auspices of DOE Grant No. DE-AC02-91-ER40648, Experimental and Theoretical Investigations of High Gradient Acceleration''. This grant supports three research tasks: Task A consists of the design, fabrication and testing of a 17GHz RF photocathode gun, which can produce 2ps electron pulses with up to 1nC of charge at 2MeV energy and at a 1OHz repetition rate. Task B supports the testing of high gradient acceleration at 33GHz structure, and Task C comprises theoretical investigations, both in support of the experimental tasks and on critical physics issues for the development of high energy linear colliders.

Wurtele, J.S.; Bekefi, G.; Chen, C.; Chen, S.C.; Temkin, R.J.

1993-01-01

123

Characterization of flow resistance in high-gradient, forested streams  

Microsoft Academic Search

Velocity and flow resistance of high-gradient, forested stream reaches in the Fraser Experimental Forest, Colorado, were characterized using Rhodamine WT dye tracing, ground-based LiDAR scans and laser theodolite surveying. Travel time and average reach velocities were computed using a spatial harmonic mean travel time, and compared to values computed using time between peaks and time between centroids. Peak velocities differed

S. E. Yochum; B. Bledsoe; G. C. David; E. E. Wohl

2009-01-01

124

IMPROVEMENT OF IMMUNOMAGNETIC SEPARATION FOR ESCHERICHIA COLI O157:H7 DETECTION BY THE PICKPEN MAGNETIC PARTICLE SEPARATION DEVICE  

Technology Transfer Automated Retrieval System (TEKTRAN)

Conventional immunomagnetic separation (IMS) procedures, which use an external magnetic source to capture magnetic particles against the side of a test tube, are labor intensive and can have poor sensitivity for the target organism due to high background microflora that is not effectively washed awa...

125

Separation of Charged Particles from Magnetic Field Lines in Two-Component Magnetic Turbulence  

NASA Astrophysics Data System (ADS)

In interplanetary space, the transport of energetic charged particles is influenced by a turbulent magnetic field. Previous studies have shown that a two-component (2D+slab) magnetic model of turbulence is a useful model for the magnetic field in the heliosphere. Normally, the diffusive behavior of charged particles in a turbulent magnetic field is observed when they approach the long time limit. The charged particles are often assumed to follow and diffuse according to the random walk of the field lines but some theories of perpendicular particle transport, such as nonlinear guiding center theory (NLGC), implicitly assume some true cross-field diffusion in which particles separate from the field line connected to their initial location. Furthermore, such cross-field diffusion is of specific interest because it is the only way that particles can diffuse across boundaries of magnetic field topology, such as the heliospheric current sheet and boundaries of interplanetary magnetic flux ropes. In this work, we study such cross-field diffusion using numerical techniques to simulate the trajectories of charged particles and magnetic field lines in two-component magnetic turbulence and to find the separation between the particles and their initial magnetic field lines. The guiding centers (GC) of the particles are computed here. Then we calculate the spreading between the GC of the particles and the trajectories of the field lines. We found that, in the pure slab turbulence, the particles stick with the magnetic field lines at which they initially start. In the 2D+slab case, the particles initially follow their initial field lines and then spread diffusively in the long time limit. We perform simulations for varying particle energy, ratio of 2D to slab fluctuations, and strength of the magnetic fluctuation in order to understand the relationship between the particle and magnetic field line trajectories. The diffusion coefficients of the particles have been calculated and compared with previous theories. This will lead to better understanding about the mechanisms of particle transport and will also help in developing a more complete transport theory of energetic charged particles in magnetic turbulence. Partially supported by the Thailand Research Fund, NSF SHINE ATM-0752135, and NASA Heliophysics Theory Program NNX08AI47G.

Chuychai, P.; Ruffolo, D. J.; Matthaeus, W. H.

2010-12-01

126

Large Scale Magnetic Separation of Solanum tuberosum Tuber Lectin from Potato Starch Waste Water  

NASA Astrophysics Data System (ADS)

A simple procedure for large scale isolation of Solanum tuberosum tuber lectin from potato starch industry waste water has been developed. The procedure employed magnetic chitosan microparticles as an affinity adsorbent. Magnetic separation was performed in a flow-through magnetic separation system. The adsorbed lectin was eluted with glycine/HCl buffer, pH 2.2. The specific activity of separated lectin increased approximately 27 times during the isolation process.

Safarik, Ivo; Horska, Katerina; Martinez, Lluis M.; Safarikova, Mirka

2010-12-01

127

SUPERCONDUCTING OPEN-GRADIENT MAGNETIC SEPARATION FOR THE PRETREATMENT OF RADIOACTIVE OR MIXED WASTE VITRIFICATION FEEDS  

EPA Science Inventory

Scientists need to gain a better understanding of the magnetic separation processes that can be used to separate deleterious constituents (crystalline, amorphous, and colloidal) in vitrification feed streams for borosilicate glass production without adding chemicals or generating...

128

Dielectric-Lined High-Gradient Accelerator Structure  

SciTech Connect

Rectangular particle accelerator structures with internal planar dielectric elements have been studied, with a view towards devising structures with lower surface fields for a given accelerating field, as compared with structures without dielectrics. Success with this concept is expected to allow operation at higher accelerating gradients than otherwise on account of reduced breakdown probabilities. The project involves studies of RF breakdown on amorphous dielectrics in test cavities that could enable high-gradient structures to be built for a future multi-TeV collider. The aim is to determine what the limits are for RF fields at the surfaces of selected dielectrics, and the resulting acceleration gradient that could be achieved in a working structure. The dielectric of principal interest in this study is artificial CVD diamond, on account of its advertised high breakdown field ({approx}2 GV/m for dc), low loss tangent, and high thermal conductivity. Experimental studies at mm-wavelengths on materials and structures for achieving high acceleration gradient were based on the availability of the 34.3 GHz third-harmonic magnicon amplifier developed by Omega-P, and installed at the Yale University Beam Physics Laboratory. Peak power from the magnicon was measured to be about 20 MW in 0.5 {micro}s pulses, with a gain of 54 dB. Experiments for studying RF high-field effects on CVD diamond samples failed to show any evidence after more than 10{sup 5} RF pulses of RF breakdown up to a tangential surface field strength of 153 MV/m; studies at higher fields were not possible due to a degradation in magnicon performance. A rebuild of the tube is underway at this writing. Computed performance for a dielectric-loaded rectangular accelerator structure (DLA) shows highly competitive properties, as compared with an existing all-metal structure. For example, comparisons were made of a DLA structure having two planar CVD diamond elements with a all-metal CERN structure HDS operating at 30 GHz. It was shown that the ratio of maximum surface electric field to accelerating field at the metal wall is only 0.35-0.4 for DLA, much smaller than the value 2.2 for HDS; and the ratio of surface magnetic field to accelerating field is 3.0 mA/V for DLA, compared with 3.45 mA/V for HDS. These values bode well for DLA in helping to avoid breakdown and to reducing pulsed surface heating and fatigue. The shunt impedance is found to be 160-175 M{Omega}/m for DLA, as compared to 99 M{Omega}/m for HDS. Conclusions are reached from this project that CVD diamond appears promising as a dielectric with a high threshold for RF breakdown, and that rectangular accelerator structures can be devised using planar CVD diamond elements that could be operated at higher acceleration gradients with low probability of RF breakdown, as compared with corresponding all-metallic structures.

Jay L. Hirshfield

2012-04-24

129

Method and apparatus for separating materials magnetically. [Patent application; iron pyrite from coal  

DOEpatents

Magnetic and nonmagnetic materials are separated by passing stream thereof past coaxial current-carrying coils which produce a magnetic field wherein intensity varies sharply with distance radially of the axis of the coils.

Hise, E.C. Jr.; Holman, A.S.; Friedlaender, F.J.

1980-11-06

130

Fabrication of high gradient insulators by stack compression  

DOEpatents

Individual layers of a high gradient insulator (HGI) are first pre-cut to their final dimensions. The pre-cut layers are then stacked to form an assembly that is subsequently pressed into an HGI unit with the desired dimension. The individual layers are stacked, and alignment is maintained, using a sacrificial alignment tube that is removed after the stack is hot pressed. The HGI's are used as high voltage vacuum insulators in energy storage and transmission structures or devices, e.g. in particle accelerators and pulsed power systems.

Harris, John Richardson; Sanders, Dave; Hawkins, Steven Anthony; Norona, Marcelo

2014-04-29

131

Development of X-band accelerating structures for high gradients  

NASA Astrophysics Data System (ADS)

Short copper standing wave (SW) structures operating at an X-band frequency have been recently designed and manufactured at the Laboratori Nazionali di Frascati of the Istituto Nazionale di Fisica Nucleare (INFN) using the vacuum brazing technique. High power tests of the structures have been performed at the SLAC National Accelerator Laboratory. In this manuscript we report the results of these tests and the activity in progress to enhance the high gradient performance of the next generation of structures, particularly the technological characterization of high performance coatings obtained via molybdenum sputtering.

Bini, S.; Chimenti, V.; Marcelli, A.; Palumbo, L.; Spataro, B.; A. Dolgashev, V.; Tantawi, S.; D. Yeremian, A.; Higashi, Y.; G. Grimaldi, M.; Romano, L.; Ruffino, F.; Parodi, R.

2012-07-01

132

Journal of Magnetism and Magnetic Materials 293 (2005) 597604 Magnetic separation in microfluidic systems using  

E-print Network

or nanolitres), they are highly portable, and they are potentially inexpensive and thus disposable [6,7]. We-encapsulated in a dielectric layer and a nickel soft magnetic yoke on top of that. ARTICLE IN PRESS www

133

Magnetic separation in microfluidic systems using microfabricated electromagnets—experiments and simulations  

Microsoft Academic Search

We present experiments and simulations of magnetic separation of magnetic beads in a microfluidic channel. The separation is obtained by microfabricated electromagnets. The results of our simulations using FEMLAB and Mathematica are compared with experimental results obtained using our own microfabricated systems.

Kristian Smistrup; Ole Hansen; Henrik Bruus; Mikkel F. Hansen

2005-01-01

134

Application of coal petrography to the evaluation of magnetically separated dry crushed coals  

SciTech Connect

In the present study the open gradient magnetic separation method has been used to beneficiate the -30 + 100 mesh fraction of two high volatile bituminous coals. The evaluation of the effectiveness of the magnetic separation for cleaning these coals is the subject of this paper. Coal petrography in combination with scanning electron microscopy and x-ray diffractometry were used to characterize the magnetically separated coal fractions. These analyses revealed that the majority of the pyrite and non-pyrite minerals were concentrated in the positive magnetic susceptibility fractions. The bulk of the starting samples (approx. 80 weight percent) were located in the negative magnetic susceptibility fractions and showed significant reductions in pyrite and non-pyritic minerals. The magnetic separation appears to effectively split the samples into relatively clean coal and refuse.

Harris, L.A.; Hise, E.C.

1981-01-01

135

Loss separation in soft magnetic composites5 O. de la Barrire1  

E-print Network

1 1 2 3 4 Loss separation in soft magnetic composites5 6 7 8 9 O. de la Barrière1 , C. Appino2 , F and their frequency dependence26 in soft magnetic composites. Two types of bonded Fe-based materials have been/or high working frequencies [3] [4]. Soft46 magnetic composites (SMCs) are therefore often proposed

Paris-Sud XI, Université de

136

Generation of high gradient wakefields in dielectric loaded structures.  

SciTech Connect

Dielectric loaded wakefield structures have potential to be used as high gradient accelerator components. Using the high current drive beam at the Argonne Wakefield Accelerator Facility, we employed cylindrical dielectric loaded wakefield structures to generate accelerating fields of up to 100 MV/m. Short electron bunches (13 ps FWHM) of up to 86 nC are used to drive these fields, either as single bunches or as bunch trains. These tested standing-wave structures have a field probe near the outer edge of the dielectric to sample the RF fields generated by the electron bunches. Monitoring of these high intensity RF fields serves to verify the absence of electric breakdown. Similar cylindrical dielectric loaded structures are used as power extractors, that is, traveling wave structures from which the RF power generated by the drive beam is efficiently coupled out.

Conde, M. E.; Antipov, S.; Franchini, F.; Gai, W.; Konecny, R.; Liu, W.; Power, J. G.; Yusof, Z.; Gao, F.; Jing, C.; High Energy Physics; Illinois Inst. of Tech.; Euclid Techlabs, LLC

2008-01-01

137

Magnetite/CdTe magnetic-fluorescent composite nanosystem for magnetic separation and bio-imaging  

NASA Astrophysics Data System (ADS)

A new synthesis protocol is described to obtain a CdTe decorated magnetite bifunctional nanosystem via dodecylamine (DDA) as cross linker. High resolution transmission electron microscopy (HRTEM), energy-dispersive x-ray spectroscopy (EDAX), vibrating sample magnetometry (VSM), Fourier transform infrared spectroscopy (FTIR), diffuse reflectance spectroscopy (DRS) and fluorescence microscopy are used to characterize the constitution, size, composition and physical properties of these superparamagnetic-fluorescent nanoparticles. These CdTe decorated magnetite nanoparticles were then functionalized with anti-epidermal growth factor receptor (EGFR) antibody to specifically target cells expressing this receptor. The EGFR is a transmembrane glycoprotein and is expressed on tumor cells from different tissue origins including human leukemic cell line Molt-4 cells. The magnetite-CdTe composite nanosystem is shown to perform excellently for specific selection, magnetic separation and fluorescent detection of EGFR positive Molt-4 cells from a mixed population. Flow cytometry and confocal laser scanning microscopy results show that this composite nanosystem has great potential in antibody functionalized magnetic separation and imaging of cells using cell surface receptor antibody.

Kale, Anup; Kale, Sonia; Yadav, Prasad; Gholap, Haribhau; Pasricha, Renu; Jog, J. P.; Lefez, Benoit; Hannoyer, Béatrice; Shastry, Padma; Ogale, Satishchandra

2011-06-01

138

Chiral magnetic microspheres purified by centrifugal field flow fractionation and microspheres magnetic chiral chromatography for benzoin racemate separation.  

PubMed

Separation of enantiomers still remains a challenge due to their identical physical and chemical properties in a chiral environment, and the research on specific chiral selector along with separation techniques continues to be conducted to resolve individual enantiomers. In our laboratory the promising magnetic chiral microspheres Fe3O4@SiO2@cellulose-2, 3-bis (3,5-dimethylphenylcarbamate) have been developed to facilitate the resolution using both its magnetic property and chiral recognition ability. In our present studies this magnetic chiral selector was first purified by centrifuge field flow fractionation, and then used to separate benzoin racemate by a chromatographic method. Uniform-sized and masking-impurity-removed magnetic chiral selector was first obtained by field flow fractionation with ethanol through a spiral column mounted on the type-J planetary centrifuge, and using the purified magnetic chiral selector, the final chromatographic separation of benzoin racemate was successfully performed by eluting with ethanol through a coiled tube (wound around the cylindrical magnet to retain the magnetic chiral selector as a stationary phase) submerged in dry ice. In addition, an external magnetic field facilitates the recycling of the magnetic chiral selector. PMID:23891368

Tian, Ailin; Qi, Jing; Liu, Yating; Wang, Fengkang; Ito, Yoichiro; Wei, Yun

2013-08-30

139

Magnetic properties and loss separation in iron-silicone-MnZn ferrite soft magnetic composites  

NASA Astrophysics Data System (ADS)

This paper investigates the magnetic and structural properties of iron-based soft magnetic composites coated with silicone-MnZn ferrite hybrid. The organic silicone resin was added to improve the flexibility of the insulated iron powder and causes better adhesion between particles to increase the mechanical properties. Scanning electron microscopy and distribution maps show that the iron particle surface is covered with a thin layer of silicone-MnZn ferrite. Silicone-MnZn ferrite coated samples have higher permeability when compared with the non-magnetic silicone resin coated compacts. The real part of permeability increases by 34.18% when compared with the silicone resin coated samples at 20 kHz. In this work, a formula for calculating the total loss component by loss separation method is presented and finally the different parts of total losses are calculated. The results show that the eddy current loss coefficient is close to each other for the silicone-MnZn ferrite, silicone resin and MnZn ferrite coated samples (0.0078

Wu, Shen; Sun, Aizhi; Xu, Wenhuan; Zou, Chao; Yang, Jun; Dong, Juan

2013-12-01

140

Magnetic properties and loss separation in iron-silicone-MnZn ferrite soft magnetic composites  

SciTech Connect

This paper investigates the magnetic and structural properties of iron-based soft magnetic composites coated with silicone-MnZn ferrite hybrid. The organic silicone resin was added to improve the flexibility of the insulated iron powder and causes better adhesion between particles to increase the mechanical properties. Scanning electron microscopy and distribution maps show that the iron particle surface is covered with a thin layer of silicone-MnZn ferrite. Silicone-MnZn ferrite coated samples have higher permeability when compared with the non-magnetic silicone resin coated compacts. The real part of permeability increases by 34.18% when compared with the silicone resin coated samples at 20 kHz. In this work, a formula for calculating the total loss component by loss separation method is presented and finally the different parts of total losses are calculated. The results show that the eddy current loss coefficient is close to each other for the silicone-MnZn ferrite, silicone resin and MnZn ferrite coated samples (0.0078

Wu, Shen; Sun, Aizhi; Xu, Wenhuan; Zou, Chao; Yang, Jun; Dong, Juan [School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing (China)

2013-12-16

141

High-Gradient Tests of the Single-Cell SC Cavity with a Feedback Waveguide  

SciTech Connect

Use of a superconducting (SC) traveling-wave accelerating (STWA) structure with a small phase advance per cell, rather than a standing-wave structure, may provide a significant increase in the accelerating gradient in the ILC linac [1]. For the same surface electric and magnetic fields, the STWA achieves an accelerating gradient 1.2 larger than TESLA-like standing-wave cavities. In addition, the STWA allows longer acceleration cavities, reducing the number of gaps between them. However, the STWA structure requires a SC feedback waveguide to return the few hundreds of MW of circulating RF power from the structure output to the structure input. A test single-cell cavity with feedback was designed and manufactured to demonstrate the possibility of proper processing to achieve a high accelerating gradient. The first results of high-gradient tests of a prototype 1.3 GHz single-cell cavity with feedback waveguide will be presented.

Yakovlev, V.; Solyak, N.; Wu, G.; Ge, M.; Gonin, I.; Khabiboulline, T.; Ozelis, J.; Rowe, A. [Fermilab, Batavia, IL 60510 (United States); Avrakhov, P.; Kanareykin, A. [Euclid TechLabs, LLC, Solon, Ohio 44139 (United States); Rathke, J. [AES, Medford, NY 11763 (United States)

2010-11-04

142

Haloing in bimodal magnetic colloids: the role of field induced phase separation , P.Kuzhir1  

E-print Network

be useful for the development of the bimodal magnetorheological fluids and of the magnetic separation to a stable fluid and back to colloidal gel with increasing nanoparticle concentration [1]. The stabilization

Boyer, Edmond

143

Magnetically separable nanoferrite-anchored glutathione: Aqueous homocoupling of arylboronic acids under microwave irradiation  

EPA Science Inventory

A highly active, stable and magnetically separable glutathione based organocatalyst provided good to excellent yields to symmetric biaryls in the homocoupling of arylboronic acids under microwave irradiation. Symmetrical biaryl motifs are present in a wide range of natural p...

144

Development of Dielectric-Based High Gradient Accelerating Structures  

SciTech Connect

High gradient accelerating structures using dielectric-lined circular waveguides have been developed for a number of years at Argonne National Laboratory. In this article, we first report the experimental results of high power rf testing on the quartz based Dielectric-Loaded Accelerating (DLA) structure carried out on Feb. 2006 at the Naval Research Laboratory. The motivation for this experiment is to test the multipactor effect on different materials under high power and high vacuum condition. Up to 12 MW pulsed rf went through the tube without breakdown. Multipactor appeared during the experiment but with different features compared to other materials like alumina. Photomultiplier Tube (PMT) measurements were introduced into the experiment for the first time to observe the light emission time and intensity. In the second part of this paper, ways to achieve higher gradient for DLA structures are proposed: 1) smaller ID and longitudinal gap free DLA structures to reduce multipactor and obtain higher gradient; 2) new coaxial type coupler to avoid dielectric gap and improve impedance matching; 3) double layered DLA structure to reduce rf loss and enhance shunt impedance as well.

Jing, C. [Euclid Techlabs, LLC, 5900 Harper Rd, Solon, OH-44139 (United States); High Energy Physics Division, Argonne National Laboratory, Argonne, IL-60439 (United States); Gai, W.; Konecny, R.; Power, J.; Liu, W. [High Energy Physics Division, Argonne National Laboratory, Argonne, IL-60439 (United States); Gold, S. H. [Plasma Physics Division, Naval Research Laboratory, Washington DC, 20375 (United States); Kinkead, A. K. [LET Corp., Washington DC, 20007 (United States); Kanareykin, A. [Euclid Techlabs, LLC, 5900 Harper Rd, Solon, OH-44139 (United States); Kazakov, S. [KEK, Tsukuba (Japan)

2006-11-27

145

Characterization of flow resistance in high-gradient, forested streams  

NASA Astrophysics Data System (ADS)

Velocity and flow resistance of high-gradient, forested stream reaches in the Fraser Experimental Forest, Colorado, were characterized using Rhodamine WT dye tracing, ground-based LiDAR scans and laser theodolite surveying. Travel time and average reach velocities were computed using a spatial harmonic mean travel time, and compared to values computed using time between peaks and time between centroids. Peak velocities differed from harmonic by an average of 12.4 percent while centroid velocities differed by -2.8 percent. Manning’s n and Darcy-Weisbach ff were computed and related to numerous potential explanatory variables. Variables that quantified bed variability, such as the relative ratio of average maximum depth to standard deviation of the residuals of the bed profile regression, were the best predictors of flow resistance in these cascade, step-pool, plane-bed streams. Individual bed variability parameters explained 72 to 80 percent of the variance in the resistance coefficients. Spatial characterization of the resistance elements in relation to the resistance coefficients was also performed.

Yochum, S. E.; Bledsoe, B.; David, G. C.; Wohl, E. E.

2009-12-01

146

Optimum shell separation for closed axial cylindrical magnetic shields  

NASA Astrophysics Data System (ADS)

The effect of shell separation on the axial shielding with closed double-shell cylindrical shields is investigated numerically. It is found that the optimum shell separation for practical, equal-thickness shields of the above type is considerably smaller than that for transverse spherical and infinitely long cylindrical shields: in most cases, air gaps equal 5%-10% of the inner shell diameter are wide enough to bring the shielding to 90% of its maximum. This indicates that closely spaced axial shields can be used without much sacrifice in performance. Taking into account the computed optimum shell separation for double-shell shields, one can easily optimize and design a compact and effective multishell shield. Based on the numerical study, an analytical approximation is suggested for the axial shielding with narrowly spaced double-shell cylindrical shields.

Paperno, Eugene; Peliwal, Saee; Romalis, Michael V.; Plotkin, Anton

2005-05-01

147

Quadrics on complex Riemannian spaces of constant curvature, separation of variables, and the Gaudin magnet  

Microsoft Academic Search

Integrable systems that are connected with orthogonal separation of variables in complex Riemannian spaces of constant curvature are considered herein. An isomorphism with the hyperbolic Gaudin magnet, previously pointed out by one of the authors, extends to coordinates of this type. The complete classification of these separable coordinate systems is provided by means of the corresponding L matrices for the

E. G. Kalnins; V. B. Kuznetsov; Willard Miller; Jr

1994-01-01

148

A bio-magnetic bead separator on glass chips using semi-encapsulated spiral electromagnets  

Microsoft Academic Search

A new planar bio-magnetic bead separator on a glass chip has been designed, fabricated and tested. The separator is composed of micromachined semi-encapsulated spiral electromagnets and fluid channels, which are separately fabricated and then bonded. The device was tested with super-paramagnetic beads of mean diameter 0.83 ?m which were suspended in a buffered solution with solid concentration 10%. When a

Trifon M. Liakopoulos; Jin-Woo Choi; Chong H. Ahn

1997-01-01

149

An on-chip magnetic bead separator using spiral electromagnets with semi-encapsulated permalloy  

Microsoft Academic Search

A new planar bio-magnetic bead separator on a glass chip has been designed, fabricated and tested. The separator is composed of micromachined semi-encapsulated spiral electromagnets and fluid channels, which have been separately fabricated and then bonded. The device was tested with super-paramagnetic beads of mean diameter 1 ?m which were suspended in a buffered solution. When a DC current of

Jin-Woo Choi; Trifon M. Liakopoulos; Chong H. Ahn

2001-01-01

150

On-chip magnetic separation of superparamagnetic beads for integrated molecular analysis  

PubMed Central

We have demonstrated a postprocessed complementary metal oxide semiconductor (CMOS) integrated circuit (IC) capable of on-chip magnetic separation, i.e., removing via magnetic forces the nonspecifically bound magnetic beads from the detection area on the surface of the chip. Initially, 4.5 ?m wide superparamagnetic beads sedimenting out of solution due to gravity were attracted to the detection area by a magnetic concentration force generated by flowing current through a conductor embedded in the IC. After sedimentation, the magnetic beads that did not bind strongly to the functionalized surface of the IC through a specific biochemical complex were removed by a magnetic separation force generated by flowing current through another conductor placed laterally to the detection area. As the spherical bead pivoted on the surface of the chip, the lateral magnetic force was further amplified by mechanical leveraging, and 50 mA of current flowing through the separation conductor placed 18 ?m away from the bead resulted in 7.5 pN of tensile force on the biomolecular tether immobilizing the bead. This force proved high enough to break nonspecific interactions while leaving specific antibody-antigen bonds intact. A sandwich capture immunoassay on purified human immunoglobulin G showed strong correlation with a control enzyme linked immunosorbent assay and a detection limit of 10 ng?ml or 70 pM. The beads bound to the detection area after on-chip magnetic separation were detected optically. To implement a fully integrated molecular diagnostics platform, the on-chip magnetic separation functionality presented in this work can be readily combine with state-of-the art CMOS-based magnetic bead detection technology. PMID:20368988

Florescu, Octavian; Wang, Kevan; Au, Patrick; Tang, Jimmy; Harris, Eva; Beatty, P. Robert; Boser, Bernhard E.

2010-01-01

151

On-chip magnetic separation of superparamagnetic beads for integrated molecular analysis  

NASA Astrophysics Data System (ADS)

We have demonstrated a postprocessed complementary metal oxide semiconductor (CMOS) integrated circuit (IC) capable of on-chip magnetic separation, i.e., removing via magnetic forces the nonspecifically bound magnetic beads from the detection area on the surface of the chip. Initially, 4.5 ?m wide superparamagnetic beads sedimenting out of solution due to gravity were attracted to the detection area by a magnetic concentration force generated by flowing current through a conductor embedded in the IC. After sedimentation, the magnetic beads that did not bind strongly to the functionalized surface of the IC through a specific biochemical complex were removed by a magnetic separation force generated by flowing current through another conductor placed laterally to the detection area. As the spherical bead pivoted on the surface of the chip, the lateral magnetic force was further amplified by mechanical leveraging, and 50 mA of current flowing through the separation conductor placed 18 ?m away from the bead resulted in 7.5 pN of tensile force on the biomolecular tether immobilizing the bead. This force proved high enough to break nonspecific interactions while leaving specific antibody-antigen bonds intact. A sandwich capture immunoassay on purified human immunoglobulin G showed strong correlation with a control enzyme linked immunosorbent assay and a detection limit of 10 ng/ml or 70 pM. The beads bound to the detection area after on-chip magnetic separation were detected optically. To implement a fully integrated molecular diagnostics platform, the on-chip magnetic separation functionality presented in this work can be readily combine with state-of-the art CMOS-based magnetic bead detection technology.

Florescu, Octavian; Wang, Kevan; Au, Patrick; Tang, Jimmy; Harris, Eva; Beatty, P. Robert; Boser, Bernhard E.

2010-03-01

152

Enhancement of magnetic separability in coal liquefaction residual solids  

Microsoft Academic Search

The conversion of coal to a clean fuel through liquefaction requires the physical separation of undissolved sulfur-rich mineral matter. The hydrogenation-liquefaction reaction produces residual solids in which the original coal impurity pyrite, FeS2, has largely been converted to pyrrhotite, Fe(1-x)S, which is a complex nonstoichiometric sulfide. By using thermomagnetic analysis and Moessbauer spectroscopy it is shown that the iron sulfide

I. S. Jacobs; L. M. Levinson

1979-01-01

153

Enhancement of magnetic separability in coal liquefaction residual solids  

Microsoft Academic Search

The conversion of coal to a clean fuel through liquefaction requires the physical separation of undissolved sulfur-rich mineral matter. The hydrogenation-liquefaction reaction produces residual solids in which the original coal impurity pyrite, FeS2, has largely been converted to pyrrhotite, Fe1?xS, which is a complex non-stoichiometric sulfide. Using thermomagnetic analysis and Mo¨ssbauer spectroscopy we show that the iron sulfide in coal

I. S. Jacobs; Lionel M. Levinson

1979-01-01

154

Separation of Uranium by an Extractant Encapsulated Magnetic Alginate Gels  

NASA Astrophysics Data System (ADS)

The aim of this work is to prepare environmentally friendly and practically applicable alginate magnetic biopolymers encapsulated tri-n-butyl phosphate (TBP) for the removal uranium ions. Some important process parameters such as initial pH, initial U(VI) concentration, adsorbent dosage, time, temperature and sorption isotherms for uranium uptake were studied and the thermodynamic parameters for U(VI) were determined.

Portakal, Z.; Gok, C.; Aytas, S.

155

Non-locality of energy separating transformations for Dirac electrons in a magnetic field  

NASA Astrophysics Data System (ADS)

We investigate a non-locality of Moss-Okninski transformation (MOT) used to separate positive and negative energy states in the 3+1 Dirac equation for relativistic electrons in the presence of a magnetic field. Properties of functional kernels generated by the MOT are analyzed and kernel non-localities are characterized by calculating their second moments parallel and perpendicular to the magnetic field. Transformed functions are described and investigated by computing their variances. It is shown that the non-locality of the energy-separating transformation in the direction parallel to the magnetic field is characterized by the Compton wavelength ?c = ?/mc. In the plane transverse to the magnetic field, the non-locality depends both on magnetic radius L = (?/eB)1/2 and ?c. The non-locality of MOT for the 2+1 Dirac equation is also considered.

Rusin, Tomasz M.; Zawadzki, Wlodek

2012-08-01

156

Hour-glass magnetic excitations induced by nanoscopic phase separation in cobalt oxides.  

PubMed

The magnetic excitations in the cuprate superconductors might be essential for an understanding of high-temperature superconductivity. In these cuprate superconductors the magnetic excitation spectrum resembles an hour-glass and certain resonant magnetic excitations within are believed to be connected to the pairing mechanism, which is corroborated by the observation of a universal linear scaling of superconducting gap and magnetic resonance energy. So far, charge stripes are widely believed to be involved in the physics of hour-glass spectra. Here we study an isostructural cobaltate that also exhibits an hour-glass magnetic spectrum. Instead of the expected charge stripe order we observe nano phase separation and unravel a microscopically split origin of hour-glass spectra on the nano scale pointing to a connection between the magnetic resonance peak and the spin gap originating in islands of the antiferromagnetic parent insulator. Our findings open new ways to theories of magnetic excitations and superconductivity in cuprate superconductors. PMID:25534540

Drees, Y; Li, Z W; Ricci, A; Rotter, M; Schmidt, W; Lamago, D; Sobolev, O; Rütt, U; Gutowski, O; Sprung, M; Piovano, A; Castellan, J P; Komarek, A C

2014-01-01

157

Hour-glass magnetic excitations induced by nanoscopic phase separation in cobalt oxides  

NASA Astrophysics Data System (ADS)

The magnetic excitations in the cuprate superconductors might be essential for an understanding of high-temperature superconductivity. In these cuprate superconductors the magnetic excitation spectrum resembles an hour-glass and certain resonant magnetic excitations within are believed to be connected to the pairing mechanism, which is corroborated by the observation of a universal linear scaling of superconducting gap and magnetic resonance energy. So far, charge stripes are widely believed to be involved in the physics of hour-glass spectra. Here we study an isostructural cobaltate that also exhibits an hour-glass magnetic spectrum. Instead of the expected charge stripe order we observe nano phase separation and unravel a microscopically split origin of hour-glass spectra on the nano scale pointing to a connection between the magnetic resonance peak and the spin gap originating in islands of the antiferromagnetic parent insulator. Our findings open new ways to theories of magnetic excitations and superconductivity in cuprate superconductors.

Drees, Y.; Li, Z. W.; Ricci, A.; Rotter, M.; Schmidt, W.; Lamago, D.; Sobolev, O.; Rütt, U.; Gutowski, O.; Sprung, M.; Piovano, A.; Castellan, J. P.; Komarek, A. C.

2014-12-01

158

Removal of freshwater microalgae by a magnetic separation method  

NASA Astrophysics Data System (ADS)

Some species of microalgae, with high growth rate and high lipid content, appear to be attractive alternatives as a feedstock for biodiesel production. The high-energy input for harvesting biomass and removing the water from the algae makes current commercial microalgal biodiesel production cost expensive. The major techniques currently employed in microalgae harvesting and recovery include centrifugation, coagulation-flocculation, bio-flocculation, filtration and screening, gravity sedimentation, and flotation. The purpose of this study was to investigate the harvesting of microalgae cells by coagulation using magnetic activated carbon, magnetite (FeO4) nanoparticles, and common chemical coagulants. Scenedesmus rubescens was selected and cultivated in 10 L flasks under continuous artificial light. Samples were taken at different operation intervals. Jar tests were conducted to investigate the effect of adsorption of microalgae on the magnetic material. The removal efficiency of microalgae was affected by the coagulants dose, stirring time and speed, and the initial microalgae concentration. The recovery of microalgae was greater in cultures with high initial microalgae concentration compared to cultures with low microalgae concentrations.

Vergini, Sofia S.; Aravantinou, Andriana F.; Manariotis, Ioannis D.

2013-04-01

159

High Temperature Superconducting Reciprocating Magnetic Separator Final Report  

SciTech Connect

In 2001, under DOE's Superconductivity Partnership Initiative (SPI), E. I. du Pont de Nemours & Co. (Dupont) was awarded a cost-share contract to build a fully functional full-scale model high temperature superconducting reciprocating magnet unit specifically designed for the koalin clay industry. After competitive bidding, American Superconductor (AMSC) was selected to provide the coil for the magnet. Dupont performed the statement of work until September 2004, when it stopped work, with the concurrence of DOE, due to lack of federal funds. DOE had paid all invoices to that point, and Dupont had provided all cost share. At this same time, Dupont determined that this program did not fit with its corporate strategies and notified DOE that it was not interesting in resuming the program when funding became available. AMSC expressed interest in assuming performance of the Agreement to Dupont and DOE, and in March 2005, this project was transferred to AMSC by DOE amendment to the original contract and Novation Agreement between AMSC and Dupont. Design drawings and some hardware components and subassemblies were transferred to AMSC. However, no funding was obligated by DOE and AMSC never performed work on the project. This report contains a summary of the work performed by Dupont up to the September 04 timeframe.

James F. Maguire

2008-06-05

160

A proposed high-gradient laser-driven electron accelerator using crossed cylindrical laser focusing  

E-print Network

A proposed high-gradient laser-driven electron accelerator using crossed cylindrical laser focusing Institute of Physics. S0003-6951 96 04141-1 With the rapid advance of laser technology, high- gradient laser adequate charges for high- energy physics applications.7 Here we proposed a similar accelerator structure

Byer, Robert L.

161

Magnetically assisted chemical separation (MACS) process: Preparation and optimization of particles for removal of transuranic elements  

SciTech Connect

The Magnetically Assisted Chemical Separation (MACS) process combines the selectivity afforded by solvent extractants with magnetic separation by using specially coated magnetic particles to provide a more efficient chemical separation of transuranic (TRU) elements, other radionuclides, and heavy metals from waste streams. Development of the MACS process uses chemical and physical techniques to elucidate the properties of particle coatings and the extent of radiolytic and chemical damage to the particles, and to optimize the stages of loading, extraction, and particle regeneration. This report describes the development of a separation process for TRU elements from various high-level waste streams. Polymer-coated ferromagnetic particles with an adsorbed layer of octyl(phenyl)-N,N-diisobutylcarbamoylmethylphosphine oxide (CMPO) diluted with tributyl phosphate (TBP) were evaluated for use in the separation and recovery of americium and plutonium from nuclear waste solutions. Due to their chemical nature, these extractants selectively complex americium and plutonium contaminants onto the particles, which can then be recovered from the solution by using a magnet. The partition coefficients were larger than those expected based on liquid[liquid extractions, and the extraction proceeded with rapid kinetics. Extractants were stripped from the particles with alcohols and 400-fold volume reductions were achieved. Particles were more sensitive to acid hydrolysis than to radiolysis. Overall, the optimization of a suitable NMCS particle for TRU separation was achieved under simulant conditions, and a MACS unit is currently being designed for an in-lab demonstration.

Nunez, L.; Kaminski, M.; Bradley, C.; Buchholz, B.A.; Aase, S.B.; Tuazon, H.E.; Vandegrift, G.F. [Argonne National Lab., IL (United States); Landsberger, S. [Univ. of Illinois, Urbana, IL (United States)

1995-05-01

162

Theory of factors limiting high gradient operation of warm accelerating structures  

SciTech Connect

This final report summarizes the research performed during the time period from 8/1/2010 to 7/31/2013. It consists of two parts describing our studies in two directions: (a) analysis of factors limiting operation of dielectric-loaded accelerating (DLA) structures where the main problem is the occurrence of multipactor on dielectric surfaces, and (b) studies of effects associated with either RF magnetic or RF electric fields which may cause the RF breakdown in high-gradient metallic accelerating structures. In the studies of DLA structures, at least, two accomplishments should be mentioned: the development of a 3D non-stationary, self-consistent code describing the multipactor phenomena and yielding very good agreement with some experimental data obtained in joint ANL/NRL experiments. In the metallic structures, such phenomena as the heating and melting of micro-particles (metallic dust) by RF electric and magnetic fields in single-shot and rep-rate regimes is analyzed. Also, such processes in micro-protrusions on the structure surfaces as heating and melting due to the field emitted current and the Nottingham effect are thoroughly investigated with the account for space charge of emitted current on the field emission from the tip.

Nusinovich, Gregory S. [University of Maryland; Antonsen, Thomas M. [University of Maryland; Kishek, Rami [University of Maryland

2014-07-25

163

Laser isotope separation of barium using an inhomogeneous magnetic field  

NASA Astrophysics Data System (ADS)

A barium atomic beam undergoes selective isotopic excitation by a dye laser to the 1P1 state. This state radiatively decays back to the ground state or to the (6s5d)D states, which are deflected out of the beam by an inhomogeneous magnetic field. The residual atomic beam is examined by a quadrupole mass spectrometer, and isotopic depletions of up to 60% are obtained using laser powers of a few hundred milliwatts. The isotopic splitting of the 1S0-->1P1 transitions for 136Ba and the F=5/2 states of 135,137Ba are measured relative to that for 138Ba and agree well with those found previously.

van Wijngaarden, W. A.; Li, J.

1994-02-01

164

Quadrics on Complex Riemannian Spaces of Constant Curvature, Separation of Variables and the Gaudin Magnet  

E-print Network

We consider integrable systems that are connected with orthogonal separation of variables in complex Riemannian spaces of constant curvature. An isomorphism with the hyperbolic Gaudin magnet, previously pointed out by one of us, extends to coordinates of this type. The complete classification of these separable coordinate systems is provided by means of the corresponding $L$-matrices for the Gaudin magnet. The limiting procedures (or $\\epsilon $ calculus) which relate various degenerate orthogonal coordinate systems play a crucial result in the classification of all such systems.

E. G. Kalnins; V. B. Kuznetsov; Willard Miller, Jr

1993-08-23

165

Flow enhanced non-linear magnetophoretic separation of beads based on magnetic susceptibility.  

PubMed

Magnetic separation provides a rapid and efficient means of isolating biomaterials from complex mixtures based on their adsorption on superparamagnetic (SPM) beads. Flow enhanced non-linear magnetophoresis (FNLM) is a high-resolution mode of separation in which hydrodynamic and magnetic fields are controlled with micron resolution to isolate SPM beads with specific physical properties. In this article we demonstrate that a change in the critical frequency of FNLM can be used to identify beads with magnetic susceptibilities between 0.01 and 1.0 with a sensitivity of 0.01 Hz(-1). We derived an analytical expression for the critical frequency that explicitly incorporates the magnetic and non-magnetic composition of a complex to be separated. This expression was then applied to two cases involving the detection and separation of biological targets. This study defines the operating principles of FNLM and highlights the potential for using this technique for multiplexing diagnostic assays and isolating rare cell types. PMID:24061548

Li, Peng; Kilinc, Devrim; Ran, Ying-Fen; Lee, Gil U

2013-11-21

166

Magnetic separation and evaluation of magnetization of Brazilian soils from different parent materials  

Microsoft Academic Search

Ten selected Brazilian soils representative of Oxisols, Ultisols, Alfisols and Inceptisols and derived from gneiss, basalt, sandstone, diabase and itabirite were sampled and examined to provide insight into the behavior of their magnetic minerals. The objective was to measure the magnetization of the sand, silt and clay fractions and to submit the clay fraction to variable magnetic fields to obtain

M. P. F. Fontes; T. S. de Oliveira; L. M. da Costa; A. A. G. Campos

2000-01-01

167

Non-locality of energy separating transformations for Dirac electrons in a magnetic field  

Microsoft Academic Search

We investigate a non-locality of Moss–Okninski transformation (MOT) used to separate positive and negative energy states in the 3+1 Dirac equation for relativistic electrons in the presence of a magnetic field. Properties of functional kernels generated by the MOT are analyzed and kernel non-localities are characterized by calculating their second moments parallel and perpendicular to the magnetic field. Transformed functions

Tomasz M Rusin; Wlodek Zawadzki

2012-01-01

168

Conceptual design of integrated microfluidic system for magnetic cell separation, electroporation, and transfection.  

PubMed

For the purposes of a successful ex vivo gene therapy we have proposed and analyzed a new concept of an integrated microfluidic system for combined magnetic cell separation, electroporation, and magnetofection. For the analysis of magnetic and electric field distribution (given by Maxwell equations) as well as dynamics of magnetically labeled cell and transfection complex, we have used finite element method directly interfaced to the Matlab routine solving Newton dynamical equations of motion. Microfluidic chamber has been modeled as a channel with height and length 1 mm and 1 cm, respectively. Bottom electrode consisted of 100 parallel ferromagnetic straps and the upper electrode was plate of diamagnetic copper. From the dynamics of magnetic particle motion we have found that the characteristic time-scales for the motion of cells (mean capture time ? 4 s) and gene complexes (mean capture time ? 3 min), when permanent magnets are used, are in the range suitable for efficient cell separation and gene delivery. The largest electric field intensity (?10 kV/m) was observed at the edges of the microelectrodes, in the close proximity of magnetically separated cells, which is optimal for subsequent cell electroporation. PMID:23260767

Durdík, Š; Kraf?ík, A; Babincová, M; Babinec, P

2013-09-01

169

Lateral-driven continuous magnetophoretic separation of blood cells  

NASA Astrophysics Data System (ADS)

We present a method for the lateral-driven continuous magnetophoretic separation of red and white blood cells from peripheral whole blood, based on their native magnetic properties. The separation is achieved using a high-gradient magnetic field, caused by a ferromagnetic wire array inlaid on glass substrate. The wire array creates an even lateral magnetophoretic force on the whole area of the microchannel, improving the separation efficiency and throughput. When the flow rate and external magnetic flux were 20 ?l/h and 0.3 T, respectively, the microseparator continuously separated out 93.9% of red blood cells and 89.2% of white blood cells from the whole blood.

Jung, Jinhee; Han, Ki-Ho

2008-12-01

170

Recovery of iron from cyanide tailings with reduction roasting-water leaching followed by magnetic separation.  

PubMed

Cyanide tailing is a kind of solid waste produced in the process of gold extraction from gold ore. In this paper, recovery of iron from cyanide tailings was studied with reduction roasting-water leaching process followed by magnetic separation. After analysis of chemical composition and crystalline phase, the effects of different parameters on recovery of iron were chiefly introduced. Systematic studies indicate that the high recovery rate and grade of magnetic concentrate of iron can be achieved under the following conditions: weight ratios of cyanide tailings/activated carbon/sodium carbonate/sodium sulfate, 100:10:3:10; temperature, 50 °C; time, 60 min at the reduction roasting stage; the liquid to solid ratio is 15:1 (ml/g), leaching at 60 °C for 5 min and stirring speed at 20 r/min at water-leaching; exciting current is 2A at magnetic separation. The iron grade of magnetic concentrate was 59.11% and the recovery ratio was 75.12%. The mineralography of cyanide tailings, roasted product, water-leached sample, magnetic concentrate and magnetic tailings were studied by X-ray powder diffraction (XRD) technique. The microstructures of above products except magnetic tailings were also analyzed by scanning electron microscope (SEM) and energy disperse spectroscopy (EDS) to help understand the mechanism. PMID:22333161

Zhang, Yali; Li, Huaimei; Yu, Xianjin

2012-04-30

171

Design of large aperture superferric quadrupole magnets for an in-flight fragment separator  

SciTech Connect

Superferric quadrupole magnets to be used for in-flight fragment separator have been designed. A quadrupole magnet triplet for beam focusing is placed in a cryostat together with superconducting correction coils. To maximize acceptance of rare isotope beams produced by projectile fragmentation, it is essential to use large-aperture quadrupole magnets. The pole tip radius is 17 cm in the current design, and we tried to enlarge the aperture with 3D analysis on magnetic fields. In the front end of the separator, where a target and beam dump are located, we plan to use two sets of quadrupole triplets made of high-Tc superconductor (HTS) operating at 20-50 K considering high radiation heat load. The HTS magnet will use warm iron poles. Both low-Tc and high-Tc superconductors are acquired for test winding, and two kinds of dewar and cryostat are under construction to perform the coil and magnet tests. The magnetic design of superferric quadrupole is mainly discussed.

Zaghloul, Aziz; Kim, Dogyun; Kim, Jangyoul; Kim, Mijung; Kim, Myeongjin; Yun, Chongcheoul; Kim, Jongwon [Rare Isotope Science Project, Institute for Basic Science, Yuseong, Daejeon, 305-811 (Korea, Republic of)

2014-01-29

172

Development of Ultra High Gradient and High Q{sub 0} Superconducting Radio Frequency Cavities  

SciTech Connect

We report on the recent progress at Jefferson Lab in developing ultra high gradient and high Q{sub 0} superconducting radio frequency (SRF) cavities for future SRF based machines. A new 1300 MHz 9-cell prototype cavity is being fabricated. This cavity has an optimized shape in terms of the ratio of the peak surface field (both magnetic and electric) to the acceleration gradient, hence the name low surface field (LSF) shape. The goal of the effort is to demonstrate an acceleration gradient of 50 MV/m with Q{sub 0} of 10{sup 10} at 2 K in a 9-cell SRF cavity. Fine-grain niobium material is used. Conventional forming, machining and electron beam welding method are used for cavity fabrication. New techniques are adopted to ensure repeatable, accurate and inexpensive fabrication of components and the full assembly. The completed cavity is to be first mechanically polished to a mirror-finish, a newly acquired in-house capability at JLab, followed by the proven ILC-style processing recipe established already at JLab. In parallel, new single-cell cavities made from large-grain niobium material are made to further advance the cavity treatment and processing procedures, aiming for the demonstration of an acceleration gradient of 50 MV/m with Q{sub 0} of 2?10{sup 10} at 2K.

Geng, Rongli [Thomas Jefferson National Accelerator Facility, Newport News, VA (United States); Clemens, William A. [Thomas Jefferson National Accelerator Facility, Newport News, VA (United States); Follkie, James E. [Thomas Jefferson National Accelerator Facility, Newport News, VA (United States); Harris, Teena M. [Thomas Jefferson National Accelerator Facility, Newport News, VA (United States); Kushnick, Peter W. [Thomas Jefferson National Accelerator Facility, Newport News, VA (United States); Machie, Danny [Thomas Jefferson National Accelerator Facility, Newport News, VA (United States); Martin, Robert E. [Thomas Jefferson National Accelerator Facility, Newport News, VA (United States); Palczewski, Ari D. [Thomas Jefferson National Accelerator Facility, Newport News, VA (United States); Perry, Era A. [Thomas Jefferson National Accelerator Facility, Newport News, VA (United States); Slack, Gary L. [Thomas Jefferson National Accelerator Facility, Newport News, VA (United States); Williams, R. S. [Thomas Jefferson National Accelerator Facility, Newport News, VA (United States); Adolphsen, C. [SLAC, Menlo Park, California, (United States); Li, Z. [SLAC, Menlo Park, California, (United States); Hao, J. K. [Peking University, Beijing (China); Li, Y. M. [Peking University, Beijing (China); Liu, K. X. [Peking University, Beijing (China)

2013-06-01

173

Magnetic characteristics of phase-separated CeO2:Co thin films  

NASA Astrophysics Data System (ADS)

Herewith, we are reporting the magnetic properties of phase-separated Co-doped CeO2 films (with a Ce:Co atomic-ratio of 0.97:0.03) grown on single-crystal SrTiO3 (001) substrates. A comparison of the magnetic characteristics of these films with those of homogenously doped CeO2:Co films of the same composition illustrates the significant differences in their magnetic behavior. These behavioral characteristics provide a model for determining if the magnetic behavior observed in this, as well as in other diluted magnetic dielectric systems, is due to homogeneous doping, a mixture of doping and transition metal cluster formation, or exists purely as a result of transition metal clustering.

Prestgard, M. C.; Siegel, G.; Ma, Q.; Tiwari, A.

2013-09-01

174

Single-step synthesis and magnetic separation of graphene and carbon nanotubes in arc discharge plasmas  

Microsoft Academic Search

The unique properties of graphene and carbon nanotubes made them the most promising nanomaterials attracting enormous attention, due to the prospects for applications in various nanodevices, from nanoelectronics to sensors and energy conversion devices. Here we report on a novel deterministic, single-step approach to simultaneous production and magnetic separation of graphene flakes and carbon nanotubes in an arc discharge by

O. Volotskova; I. Levchenko; A. Shashurin; Y. Raitses; K. Ostrikov; M. Keidar

2010-01-01

175

Separation and enrichment of enantiopure from racemic compounds using magnetic levitation.  

PubMed

Crystallization of a solution with high enantiomeric excess can generate a mixture of crystals of the desired enantiomer and the racemic compound. Using a mixture of S-/RS-ibuprofen crystals as a model, we demonstrated that magnetic levitation (MagLev) is a useful technique for analysis, separation and enantioenrichment of chiral/racemic products. PMID:24875274

Yang, Xiaochuan; Wong, Shin Yee; Bwambok, David K; Atkinson, Manza B J; Zhang, Xi; Whitesides, George M; Myerson, Allan S

2014-07-18

176

Calibration of analyzing magnet for beam energy measurement using the recoil mass separator HIRA  

NASA Astrophysics Data System (ADS)

Beam energy measurements have been carried out using the energy achromatic recoil mass separator HIRA at NSC. The energy was obtained from a measurement of the time-of-flight through HIRA which offers a flight distance of about 8.8 m. The method is quite useful for the calibration of the analyzer magnet over the entire operating range.

Madhavan, N.; Das, J. J.; Sugathan, P.; Kataria, D. O.; Avasthi, D. K.; Mandal, A.; Sinha, A. K.

1996-02-01

177

Preparation and characterization of chemically functionalized silica-coated magnetic nanoparticles as a DNA separator.  

PubMed

The work describes a simple and convenient process for highly efficient and direct DNA separation with functionalized silica-coated magnetic nanoparticles. Iron oxide magnetic nanoparticles and silica-coated magnetic nanoparticles were prepared uniformly, and the silica coating thickness could be easily controlled in a range from 10 to 50 nm by changing the concentration of silica precursor (TEOS) including controlled magnetic strength and particle size. A change in the surface modification on the nanoparticles was introduced by aminosilanization to enhance the selective DNA separation resulting from electrostatic interaction. The efficiency of the DNA separation was explored via the function of the amino-group numbers, particle size, the amount of the nanoparticles used, and the concentration of NaCl salt. The DNA adsorption yields were high in terms of the amount of triamino-functionalized nanoparticles used, and the average particle size was 25 nm. The adsorption efficiency of aminofunctionalized nanoparticles was the 4-5 times (80-100%) higher compared to silica-coated nanoparticles only (10-20%). DNA desorption efficiency showed an optimum level of over 0.7 M of the NaCl concentration. To elucidate the agglomeration of nanoparticles after electrostatic DNA binding, the Guinier plots were calculated from small-angle X-ray diffractions in a comparison of the results of energy diffraction TEM and confocal laser scanning microscopy. Additionally, the direct separation of human genomic DNA was achieved from human saliva and whole blood with high efficiency. PMID:19099431

Kang, Kiho; Choi, Jinsub; Nam, Joong Hee; Lee, Sang Cheon; Kim, Kyung Ja; Lee, Sang-Won; Chang, Jeong Ho

2009-01-15

178

Low-Field Magnetic Separation of Monodisperse Fe3O4 Nanocrystals  

E-print Network

William W. Yu,1 Arjun Prakash,2 Joshua C. Falkner,1 Sujin Yean,3 Lili Cong,3 Heather J. Shipley,3 Amy Kan-of-use water purification and the simultaneous separation of complex mixtures. High­surface area with arsenic removal from water by orders of magnitude. Additionally, the size dependence of magnetic

179

High intensity magnetic separation for the clean-up of a site polluted by lead metallurgy.  

PubMed

The industrial history in the district of Linares (Spain) has had a severe impact on soil quality. Here we examined soil contaminated by lead and other heavy metals in "La Cruz" site, a brownfield affected by metallurgical residues. Initially, the presence of contaminants mainly associated with the presence of lead slag fragments mixed with the soil was evaluated. The subsequent analysis showed a quasi-uniform distribution of the pollution irrespective of the grain-size fractions. This study was accompanied by a characterization of the lead slag behavior under the presence of a magnetic field. Two main magnetic components were detected: first a ferromagnetic and/or ferrimagnetic contribution, second a paramagnetic and/or antiferromagnetic one. It was also established that the slag was composed mainly of lead spherules and iron oxides embedded in a silicate matrix. Under these conditions, the capacity of magnetic separation to remove pollutants was examined. Therefore, two high intensity magnetic separators (dry and wet devices, respectively) were used. Dry separation proved to be successful at decontaminating soil in the first stages of a soil washing plant. In contrast, wet separation was found effective as a post-process for the finer fractions. PMID:23357508

Sierra, C; Martínez, J; Menéndez-Aguado, J M; Afif, E; Gallego, J R

2013-03-15

180

Residual Separation of Magnetic Fields Using a Cellular Neural Network Approach  

Microsoft Academic Search

- In this paper, a Cellular Neural Network (CNN) has been applied to a magnetic regional\\/residual anomaly separation problem. CNN is an analog parallel computing paradigm defined in space and characterized by the locality of connections between processing neurons. The behavior of the CNN is defined by the template matrices A, B and the template vector I. We have optimized

A. M. Albora; A. Özmen; O. N. Uçan

2001-01-01

181

Magnetic separation of Dy(III) ions from homogeneous aqueous solutions  

NASA Astrophysics Data System (ADS)

The possibility to enrich paramagnetic dysprosium(III) ions in a magnetic field gradient is proved by means of interferometry, which may open the route for a magnetic separation of rare earth ions from aqueous solutions. The separation dynamics are studied for three different concentrations of DyCl3 and compared with those found recently in a sulphate solution of the 3d ion Mn(II). In view of the similar-sized hydration spheres for Dy(III) and Mn(II), the slower separation dynamics in DyCl3 is attributed to both a higher densification coefficient and the strong impact of Brownian motion due to the absence of ion-pair clusters.

Pulko, B.; Yang, X.; Lei, Z.; Odenbach, S.; Eckert, K.

2014-12-01

182

Velocity prediction in high-gradient channels Steven E. Yochum a,  

E-print Network

Velocity prediction in high-gradient channels Steven E. Yochum a, , Brian P. Bledsoe a , Gabrielle by Geoff Syme, Editor-in-Chief Keywords: Velocity Flow resistance Steep channels Step-pool Mountain streams

Bledsoe, Brian

183

Magnetic materials as sorbents for metal/metalloid preconcentration and/or separation. A review.  

PubMed

The use of magnetic materials in solid phase extraction has received considerable attention in recent years taking into account many advantages arising from the inherent characteristics of magnetic particles. Magnetic solid phase extraction (MSPE) methodology overcomes problems such as column packing and phase separation, which can be easily performed by applying an external magnetic field. The use of magnetic particles in automatic systems is growing over the last few years making the on-line operation of MSPE a promising technique in the frame of green chemistry. This article aims to provide all recent progress in the research of novel magnetic materials as sorbents for metal preconcentration and determination coupled with different detection systems as well as their implementation in sequential injection and microfluidic systems. In addition, a description of preparation, characterization as well as applications of various types of magnetic materials, either with organic or inorganic coating of the magnetic core, is presented. Concluding remarks and future trends are also commented. PMID:23856225

Giakisikli, Georgia; Anthemidis, Aristidis N

2013-07-30

184

SEPARATION OF VARIABLES AND THE XXZ GAUDIN MAGNET E.G. KALNINS, V.B. KUZNETSOV and WILLARD MILLER, Jr.  

E-print Network

SEPARATION OF VARIABLES AND THE XXZ GAUDIN MAGNET E.G. KALNINS, V.B. KUZNETSOV and WILLARD MILLER, Minnesota 55455, USA. Abstract. In this work we generalise previous results connecting (rational) Gaudin the relationship between the separable systems and the Gaudin magnet [4,9] integrable systems models has been

185

SEPARATION OF VARIABLES AND THE XXZ GAUDIN MAGNET E.G. KALNINS, V.B. KUZNETSOV and WILLARD MILLER, Jr.  

E-print Network

SEPARATION OF VARIABLES AND THE XXZ GAUDIN MAGNET E.G. KALNINS, V.B. KUZNETSOV and WILLARD MILLER, Minnesota 55455, USA. Abstract. In this work we generalise previous results connecting (rational) Gaudin between the separable systems and the Gaudin magnet [4,9] integrable systems models has been established

186

Magnetic separation of proteins by a self-assembled supramolecular ternary complex.  

PubMed

The easy and effective separation of proteins from a mixture is crucial in proteomics. A supramolecular method is described to selectively capture and precipitate one protein from a protein mixture upon application of a magnetic field. A multivalent complex self-assembles in a dilute aqueous solution of three components: magnetic nanoparticles capped with cyclodextrin, non-covalent cross-linkers with an adamantane and a carbohydrate moiety, and lectins. The self-assembled ternary complex is precipitated in a magnetic field and readily redispersed with the aid of a non-ionic surfactant and competitive binding agents. This strategy to purify proteins by supramolecular magnetic precipitation is highly selective and efficient. PMID:25250697

Samanta, Avik; Ravoo, Bart Jan

2014-11-17

187

Separation Nanotechnology of Diethylenetriaminepentaacetic Acid Bonded Magnetic Nanoparticles for Spent Nuclear Fuel  

SciTech Connect

A nanomagnetic separation method based on Diethylenetriaminepentaacetic acid (DTPA) conjugated with magnetic nanoparticles (MNPs) is studied for application in spent nuclear fuel separation. The high affinity of DTPA towards actinides aids in separation from the highly acidic medium of nuclear waste. The solubility and magnetization of particles at low pH is protected by encapsulating them in silica layer. Surface functionalization of silica coated particles with polyamines enhances the loading capacity of the chelators on MNPs. The particles were characterized before and after surface modification using transmission electron microscopy (TEM), helium ion microscopy (HIM), Fourier transform-infrared (FT-IR) spectrometry, and X-ray diffractometry. The coated and uncoated samples were studied using vibrating sample magnetometer (VSM) to understand the change in magnetic properties due to the influence of the surface functionalization. The hydrodynamic size and surface charge of the particles are investigated using Dynamic Light Scattering (DLS). The uptake behavior of Am(III), Pu(IV), U(VI), and Np(V) from 0.1M NaNO3 solution was investigated. The sorption result shows the strong affinity of DTPA towards Am(III) and Pu(IV) by extracting 97% and 80% of actinides, respectively. The high removal efficiency and fast uptake of actinides make the chelator conjugated MNPs an effective method for spent nuclear fuel separation.

Kaur, Maninder [Idaho Univ., Moscow, ID (United States); Johnson, Andrew [Idaho Univ., Moscow, ID (United States); Tian, Guoxin [Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States); Jiang, Weilin [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Rao, Linfeng [Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States); Paszczynski, Andrzej [Idaho Univ., Moscow, ID (United States); Qiang, You [Center for Advanced Energy Studies, Idaho Falls, ID (United States); Idaho Univ., Moscow, ID (United States)

2013-01-15

188

SLIM, Short-pulse Technology for High Gradient Induction Accelerators  

SciTech Connect

The conclusions of this paper are: (1) The gradient of the SLIM-based technology is believed to be achievable in the same range as it is for the gradient of a modern rf-linac technology ({approx}100 MeV per meter). (2) The SLIM concept is based on the nsec TEM pulse mode operation with no laser or rf systems. (3) Main components of SLIM are not stressed while the energy is pumped into the induction system. Components can accept the hard environment conditions such as a radiation dose, mismatch, hard electromagnetic nose level, etc. Only for several nanoseconds the switch is OFF and produces a stress in the induction system. At that time, the delivery of energy to the beam takes place. (4) The energy in the induction system initially is storied in the magnetic field when the switch is ON. That fact makes another benefit: a low voltage power supplies can be used. The reliability of a lower voltage power supply is higher and they are cheaper. (5) The coreless SLIM concept offers to work in the MHz range of repetition rate. The induction system has the high electric efficiency (much higher than the DWA). (6) The array of lined up and activated SLIM cells is believed to be a solid state structure of novel accelerating technology. The electron-hole plasma in the high power solid state structure is precisely controlled by the electromagnetic process of a pulsed power supply.

Krasnykh, A.; /SLAC; Kardo-Sysoev, A.; /Ioffe Phys. Tech. Inst.; Arntz, F.; /Diversified Tech., Bedford

2009-12-09

189

On-chip micro-electromagnets for magnetic-based bio-molecules separation  

NASA Astrophysics Data System (ADS)

This paper reports a comprehensive theoretical, finite element and measurement analysis of different designs of planar micro-electromagnets for bio-molecular manipulation. The magnetic field due to current flowing in complex shapes of current-carrying conductors have been calculated analytically, simulated using finite-element analysis (FEA), and measured using the superconducting quantum interference device technique (SQUID). A comparison of the theoretical and measured magnetic field strength and patterns is presented. The planar electromagnets have been fabricated using patterned Al 2 ?m thick. The aim of the study is to explore and optimize the geometrical and structural parameters of planar electromagnets that give rise to the highest magnetic fields and forces for magnetic micro-beads manipulation. Magnetic beads are often used in biochemical assays for separation of bio-molecules. Typical beads are 0.2- 10 ?m in diameter and have superparamagnetic properties. Increasing the intensity of the magnetic field generated by a coil by injection a larger current is not the most suitable solution as the maximum current is limited by Joule heating. Consequently, in order to maximize the field for a given current, one should optimize the geometry of the coil, as this is an extremely significant factor in determining the magnetic field intensity in 2D planar designs. The theoretical and measured results of this work show that the meander micro-electromagnet with mesh-shaped winding profile produces the strongest magnetic field (about 2.7 ?T for a current intensity of 6 mA) compared with other meander designs, such as the serpentine and rosette-shaped ones. The magnetic fields of these three types of meander-shaped micro-electromagnets were compared theoretically with that produced by a spiral micro-electromagnet whose technological realization is more complicated and costly due to the fact that it requires an additional insulation layer with a contact window and a second patterned metal layer as a via. Nevertheless, the spiral design produces a much stronger magnetic field up to five times larger than that of the mesh-shaped micro-electromagnet for the same current and electromagnet area. The measured results strongly agree with these conclusions resulted from the theoretical analysis. The results presented in this paper provide a solid and useful basis for the design of a micro-fluidic bio-molecule separation and detection system using magnetic fields and magnetic beads.

Ramadan, Qasem; Samper, Victor; Poenar, Daniel; Yu, Chen

2004-10-01

190

Combined performance of biochar sorption and magnetic separation processes for treatment of chromium-contained electroplating wastewater.  

PubMed

Magnetic biochar was prepared with eucalyptus leaf residue remained after essential oil being extracted. Batch experiments were conducted to examine the capacity of the magnetic biochar to remove Cr (VI) from electroplating wastewater and to be separated by an external magnetic field. The results show that the initial solution pH plays an important role on both sorption and separation. The removal rates of Cr (VI), total Cr, Cu (II), and Ni (II) were 97.11%, 97.63%, 100% and 100%, respectively. The turbidity of the sorption-treated solution was reduced to 21.8NTU from 4075NTU after 10min magnetic separation. The study also confirms that the magnetic biochar still retains the original magnetic separation performance after the sorption process. PMID:25463783

Wang, Sheng-Ye; Tang, Yan-Kui; Li, Kun; Mo, Ya-Yuan; Li, Hao-Feng; Gu, Zhan-Qi

2014-10-01

191

Magnetic Field Separation Around Planets Using an Adjoint-Method Approach  

NASA Astrophysics Data System (ADS)

The two spacecraft of the BepiColombo mission will reach planet Mercury in 2022. The magnetometers on-board these polar orbiting spacecraft will provide a detailed map of the magnetic field in Mercury's environment. Unfortunately, a separation of the magnetic field into internal and external parts using the classical Gauss-algorithm is not possible due to strong electric currents in the orbit region of the spacecraft. These currents are due to the interaction of the solar wind with Mercury's planetary magnetic field. We use an MHD code to simulate this interaction process. This requires a first choice of Mercury's planetary field which is used and modified until the simulation results fit to the actual measurements. This optimization process is carried out most efficiently using an adjoint-method. The adjoint-method is well known for its low computational cost in order to determine sensitivities required for the minimization. In a first step, the validity of our approach to separate magnetic field contributions into internal and external parts is demonstrated using synthetic generated data. Furthermore, we apply our approach to satellite measurements of the Earth's magnetic field. We can compare the results with the well known planetary field of the Earth to prove practical suitability.

Nabert, Christian; Glassmeier, Karl-Heinz; Heyner, Daniel; Othmer, Carsten

192

Measurement of the magnetic interaction between two bound electrons of two separate ions  

NASA Astrophysics Data System (ADS)

Electrons have an intrinsic, indivisible, magnetic dipole aligned with their internal angular momentum (spin). The magnetic interaction between two electronic spins can therefore impose a change in their orientation. Similar dipolar magnetic interactions exist between other spin systems and have been studied experimentally. Examples include the interaction between an electron and its nucleus and the interaction between several multi-electron spin complexes. The challenge in observing such interactions for two electrons is twofold. First, at the atomic scale, where the coupling is relatively large, it is often dominated by the much larger Coulomb exchange counterpart. Second, on scales that are substantially larger than the atomic, the magnetic coupling is very weak and can be well below the ambient magnetic noise. Here we report the measurement of the magnetic interaction between the two ground-state spin-1/2 valence electrons of two 88Sr+ ions, co-trapped in an electric Paul trap. We varied the ion separation, d, between 2.18 and 2.76 micrometres and measured the electrons' weak, millihertz-scale, magnetic interaction as a function of distance, in the presence of magnetic noise that was six orders of magnitude larger than the magnetic fields the electrons apply on each other. The cooperative spin dynamics was kept coherent for 15 seconds, during which spin entanglement was generated, as verified by a negative measured value of -0.16 for the swap entanglement witness. The sensitivity necessary for this measurement was provided by restricting the spin evolution to a decoherence-free subspace that is immune to collective magnetic field noise. Our measurements show a d-3.0(4) distance dependence for the coupling, consistent with the inverse-cube law.

Kotler, Shlomi; Akerman, Nitzan; Navon, Nir; Glickman, Yinnon; Ozeri, Roee

2014-06-01

193

Measurement of the magnetic interaction between two bound electrons of two separate ions.  

PubMed

Electrons have an intrinsic, indivisible, magnetic dipole aligned with their internal angular momentum (spin). The magnetic interaction between two electronic spins can therefore impose a change in their orientation. Similar dipolar magnetic interactions exist between other spin systems and have been studied experimentally. Examples include the interaction between an electron and its nucleus and the interaction between several multi-electron spin complexes. The challenge in observing such interactions for two electrons is twofold. First, at the atomic scale, where the coupling is relatively large, it is often dominated by the much larger Coulomb exchange counterpart. Second, on scales that are substantially larger than the atomic, the magnetic coupling is very weak and can be well below the ambient magnetic noise. Here we report the measurement of the magnetic interaction between the two ground-state spin-1/2 valence electrons of two (88)Sr(+) ions, co-trapped in an electric Paul trap. We varied the ion separation, d, between 2.18 and 2.76 micrometres and measured the electrons' weak, millihertz-scale, magnetic interaction as a function of distance, in the presence of magnetic noise that was six orders of magnitude larger than the magnetic fields the electrons apply on each other. The cooperative spin dynamics was kept coherent for 15 seconds, during which spin entanglement was generated, as verified by a negative measured value of -0.16 for the swap entanglement witness. The sensitivity necessary for this measurement was provided by restricting the spin evolution to a decoherence-free subspace that is immune to collective magnetic field noise. Our measurements show a d(-3.0(4)) distance dependence for the coupling, consistent with the inverse-cube law. PMID:24943952

Kotler, Shlomi; Akerman, Nitzan; Navon, Nir; Glickman, Yinnon; Ozeri, Roee

2014-06-19

194

Review and evaluation of extractants for strontium removal using magnetically assisted chemical separation  

SciTech Connect

A literature review on extractants for strontium removal was initially performed at Northern Illinois University to assess their potential in magnetically assisted chemical separation. A series of potential strontium extractants was systematically evaluated there using radioanalytical methods. Initial experiments were designed to test the uptake of strontium from nitric acid using several samples of magnetic extractant particles that were coated with various crown ether ligands. High partition coefficient (K{sub d}) values for stimulant tank waste were obtained. Further studies demonstrated that the large partitioning was due to uncoated particles.

Bauer, C.B.; Rogers, R.D. [Northern Illinois Univ., De Kalb, IL (United States). Dept. of Chemistry; Nunez, L.; Ziemer, M.D.; Pleune, T.T.; Vandegrift, G.F. [Argonne National Lab., IL (United States)

1995-11-01

195

Preparation of thermosensitive polymer magnetic particles and their application in protein separations.  

PubMed

This paper presents a kind of thermoresponsive polymeric magnetic particles for protein separations. The magnetofluids were directly encapsulated in hollow particles constructed by self-assembly of rod-coil poly(ethylene glycol)-poly(N-isopropylacrylamide)/?-cyclodextrin (PEG-PNIPAM/?-CD) complexes. The resulting particles showed reversible protein absorption/desorption capacity because the reversible thermo-sensitivity of PNIPAM. Above the lower critical solution temperature (LCST) of PNIPAM, these particles showed high absorptive capacities and adsorption was done at lower temperature. The protein-laden particles are readily removed from the feed solution in a magnetic field. PMID:25222511

Luo, Ling; Zhang, Hong-Su; Liu, Yan; Ha, Wei; Li, Luo-Hao; Gong, Xiao-Lei; Li, Bang-Jing; Zhang, Sheng

2014-12-01

196

Magnetic Tilts and Polarity Separations in Sunspot Groups and Active Regions the Cycle 23  

NASA Astrophysics Data System (ADS)

We present the analysis of magnetic tilts in active regions and sunspot groups for 1996-2005 that are automatically extracted from the Solar Feature Catalogues (http://solar.inf.brad.ac.uk ). We investigate the statistical variations of magnetic field tilt in sunspot groups and whole active regions, their longitudinal and latitudinal distributions, drifts and daily polarity separation during different phases of the solar cycle 23. The classification results are compared with the similar research for the previous cycles and the specifics on the cycle 23 is discussed in conjunction to the solar dynamo theory.

Zharkov, S. I.; Zharkova, V. V.

2006-08-01

197

A simple magnetic separation method for high-yield isolation of pure primary microglia.  

PubMed

Microglial cells play a dynamic role in the brain beyond their established function of immune surveillance. Activated microglia play key roles in neural development, neuroinflammation, neural repair and neurotoxicity. They are particularly important in several neurodegenerative diseases in which sustained microglial activation contributes to the progression of neurodegenerative processes. Consequently, understanding microglial function in CNS health and disease has become an area of active research in recent years. However, a significant obstacle to progress in this field has been the inherent difficulties in obtaining large amounts of primary microglial cells to routinely perform mechanistic studies and characterize signaling pathways regulating the dynamics of microglial activation. Herein, we describe a novel column-free magnetic separation protocol for high-yield isolation of primary microglia from mouse postnatal mixed glial cultures. The procedure is based on optimized culture conditions that enable high microglial cell densities in confluent mixed glial cultures followed by highly efficient recovery of pure microglia by magnetic separation. The novel column-free magnetic separation system utilizes tetrameric antibody complexes (TAC) with dual specificity for CD11b-PE labeled microglia and dextran magnetic nanoparticles. An FcR blocker (anti-CD16/32) is added to enhance the purity of the microglial separation by preventing non-specific labeling of other cell types. This procedure yields on average >3×10? microglial cells per mouse pup, with a remarkable purity of 97% and recovery of around 87% of microglia from the mixed glial population. Importantly, the microglia obtained by this method are fully functional and respond like cells obtained by conventional isolation techniques. PMID:21074565

Gordon, Richard; Hogan, Colleen E; Neal, Matthew L; Anantharam, Vellareddy; Kanthasamy, Anumantha G; Kanthasamy, Arthi

2011-01-15

198

Spin-charge separation in two-dimensional frustrated quantum magnets.  

PubMed

The dynamics of a mobile hole in two-dimensional frustrated quantum magnets is investigated by exact diagonalization techniques. Our results provide evidence for spin-charge separation upon doping the kagome lattice, a prototype of a spin liquid. In contrast, in the checkerboard lattice, a symmetry broken valence bond crystal, a small quasiparticle peak is seen for some crystal momenta, a finding interpreted as a restoration of weak holon-spinon confinement. PMID:15245179

Läuchli, Andreas; Poilblanc, Didier

2004-06-11

199

Magnetic properties and loss separation in iron powder soft magnetic composite materials  

Microsoft Academic Search

New developments in powder metallurgical composites make soft magnetic composite (SMC) material interesting for application in electrical machines, when combined with new machine design rules and new production techniques. In order to establish these design rules, one must pay attention to electromagnetic loss characteristics of SMC material. In this work, five different series of iron based SMCs are produced and

Marc de Wulf; Ljubomir Anestiev; Luc Dupré; Ludo Froyen; Jan Melkebeek

2002-01-01

200

Particle Segregation in a Flowing Suspension Subject to High-Gradient Strong Electric Fields  

NASA Technical Reports Server (NTRS)

The widespread use of electro-hydrodynamic devices and processes emphasizes a critical need for developing a comprehensive predictive theory capable of improving our fundamental understanding of the behavior of a suspension subject to an AC electric field and shear, and of facilitating the design and optimization of such devices. The currently favored approach to the qualitative interpretation of the AC field driven manipulation of suspensions is based on a model which considers only the force exerted on a single particle by an external field and neglects the field-induced and hydrodynamic interparticle interactions both being inversely proportional to the interparticle distance raised to the power three. On the other hand, the purpose of the field-induced separation is to concentrate particles in certain regions of a device. This clearly raises the fundamental question regarding the extent to which we can neglect these slow decaying electrical and hydrodynamic collective interactions and rely on the predictions of a single-particle model. Another important issue that still remains open is how to characterize the polarization of a particle exposed to a strong electric field. The presentation will address both these questions. Experiments were conducted in a parallel-plate channel in which a 10(exp -3) (v/v) suspension of heavy, positively polarized Al2O3 spheres was exposed to an AC field under conditions such that the field lines were arranged in the channel cross-section perpendicular to the streamlines of the main flow. To reduce the effects of the gravitational settling of the particles, the channel was slowly rotated (4 rpm) around a horizontal axis. Following the application of a high-gradient strong AC field (approx. kV/mm), the particles were found to move towards both the high-voltage (HV) and grounded (GR) electrodes and to form 'bristles' along their edges.

Acrivos, Andreas; Qiu, Zhiyong; Khusid, Boris; Markarian, Nikolai

2002-01-01

201

SERS-fluorescence joint spectral encoded magnetic nanoprobes for multiplex cancer cell separation.  

PubMed

A new kind of cancer cell separation method is demonstrated, using surface-enhanced Raman scattering (SERS) and fluorescence dual-encoded magnetic nanoprobes. The designed nanoprobes can realize SERS-fluorescence joint spectral encoding (SFJSE) and greatly improve the multiplexing ability. The nanoprobes have four main components, that is, the magnetic core, SERS generator, fluorescent agent, and targeting antibody. These components are assembled with a multi-layered structure to form the nanoprobes. Specifically, silica-coated magnetic nanobeads (MBs) are used as the inner core. Au core-Ag shell nanorods (Au@Ag NRs) are employed as the SERS generators and attached on the silica-coated MBs. After burying these Au@Ag NRs with another silica layer, CdTe quantum dots (QDs), that is, the fluorescent agent, are anchored onto the silica layer. Finally, antibodies are covalently linked to CdTe QDs. SFJSE is fulfilled by using different Raman molecules and QDs with different emission wavelengths. By utilizing four human cancer cell lines and one normal cell line as the model cells, the nanoprobes can specifically and simultaneously separate target cancer cells from the normal ones. This SFJSE-based method greatly facilitates the multiplex, rapid, and accurate cancer cell separation, and has a prosperous potential in high-throughput analysis and cancer diagnosis. PMID:24862088

Wang, Zhuyuan; Zong, Shenfei; Chen, Hui; Wang, Chunlei; Xu, Shuhong; Cui, Yiping

2014-11-01

202

Conjugates of magnetic nanoparticle-actinide specific chelator for radioactive waste separation.  

PubMed

A novel nanotechnology for the separation of radioactive waste that uses magnetic nanoparticles (MNPs) conjugated with actinide specific chelators (MNP-Che) is reviewed with a focus on design and process development. The MNP-Che separation process is an effective way of separating heat generating minor actinides (Np, Am, Cm) from spent nuclear fuel solution to reduce the radiological hazard. It utilizes coated MNPs to selectively adsorb the contaminants onto their surfaces, after which the loaded particles are collected using a magnetic field. The MNP-Che conjugates can be recycled by stripping contaminates into a separate, smaller volume of solution, and then become the final waste form for disposal after reusing number of times. Due to the highly selective chelators, this remediation method could be both simple and versatile while allowing the valuable actinides to be recovered and recycled. Key issues standing in the way of large-scale application are stability of the conjugates and their dispersion in solution to maintain their unique properties, especially large surface area, of MNPs. With substantial research progress made on MNPs and their surface functionalization, as well as development of environmentally benign chelators, this method could become very flexible and cost-effective for recycling used fuel. Finally, the development of this nanotechnology is summarized and its future direction is discussed. PMID:24070142

Kaur, Maninder; Zhang, Huijin; Martin, Leigh; Todd, Terry; Qiang, You

2013-11-01

203

Separation of uranium from nitric and hydrochloric acid solutions with extractant-coated magnetic microparticles.  

SciTech Connect

The magnetically assisted chemical separation (MACS) process utilizes selective magnetic microparticle composites to separate dissolved metals from solution. In this study, MACS particles were coated with neutral and acidic organophosphorus extractants,octyl(phenyl)-N,N-diisobutylcarbamoylmethyl phosphine oxide (CMPO), tributyl phosphate (TBP), trioctylphosphine oxide (TOPO), and bis(2-ethyl-hexyl)phosphoric acid (D{sub 2}EHPA or HDEHP) and were evaluated for the separation of uranyl ions from nitric- and hydrochloric-acid solutions. The results suggest that a synergistic interaction between the particle surface and solvent coating may explain why the particles display, in some cases, orders of magnitude of higher partitioning coefficients than are estimated from solvent-extraction measurements. Particles coated with TBP and those coated with a combination of TOPO and D{sub 2}EHPA displayed the most desirable characteristics for removing uranium from dilute acid environments typical of contaminated groundwater. Uranium separation from moderate to highly acidic waste streams typical of Department of Energy (DOE) nuclear wastes is best accomplished using particles coated with a combination of CMPO and TBP.

Kaminski, M. D.; Nunez, L.; Chemical Engineering

2000-01-01

204

Cesium separation from contaminated milk using magnetic particles containing crystalline silicotitantes.  

SciTech Connect

The Chernobyl nuclear reactor disaster in 1986 contaminated vast regions of prime grazing land. Subsequently, milk produced in the region has been contaminated with small amounts of the long-lived fission product cesium-137, and the Ukraine is seeking to deploy a simple separation process that will remove the Cs and preserve the nutritional value of the milk. Tiny magnetic particles containing crystalline silicotitanates (CST) have been manufactured and tested to this end. The results show that partitioning efficiency is optimized with low ratios of particle mass to volume. To achieve 90% Cs decontamination in a single-stage process, <3 g of magnetic CST per l milk is sufficient with a 30-min mixing time. A two-stage process would utilize <0.4 g/l per stage. The modeling of the magnetic CST system described herein can be achieved rather simply which is important for deployment in the affected Ukraine region.

Nunez, L.; Kaminski, M.; Chemical Engineering

2000-11-01

205

Structural studies, magnetic properties and loss separation in iron–phenolicsilane soft magnetic composites  

Microsoft Academic Search

In this work, six different series of iron based soft magnetic composites are produced and studied: (1) passive iron powder; (2) passive iron powder-0.7% resin with coupling agent; (3) passive iron powder-0.7% resin without coupling agent; (4) passive iron powder-1.5% resin with coupling agent; (5) passive iron powder-1.5% resin without coupling agent; (6) pure iron-1.5% resin. The specimens were shaped

A. H. Taghvaei; H. Shokrollahi; K. Janghorban

2010-01-01

206

Experimental and theoretical investigation of high gradient acceleration. Progress report, June 1, 1991--February 1, 1992  

SciTech Connect

This report contains a technical progress summary of the research conducted under the auspices of DOE Grant No. DE-FG0291ER-40648. ``Experimental and Theoretical Investigations of High Gradient Acceleration.`` This grant supports three research tasks: Task A consists of the design and fabrication of a 17GHz of photocathode gun, Task B supports the testing of high gradient acceleration using a 33GHz structure, and Task C comprises theoretical investigations, both in support of the experimental tasks and on critical physics issues for the development of high energy linear colliders. This report is organized as follows. The development of an rf gun design and research progress on the picosecond laser system is summarized in Sec. 2, the status of the studies of the LBL/Haimson high gradient structure, using a 50 MW free-electron laser is summarized in Sec. 3, and theoretical research progress is described in Sec. 4. Supporting material is contained in Appendices A-G.

Bekefi, G.; Chen, C.; Chen, S.; Danly, B.; Temkin, R.J.; Wurtele, J.S.

1992-02-01

207

Core-shell magnetic nanoparticles: a comparative study based on silica and polydopamine coating for magnetic bio-separation platforms.  

PubMed

Core-shell magnetic nanoparticles (MNPs) offer tremendous opportunities in a large range of applications in biomedicine due to their superior magnetic properties, biocompatibility and suitability for modification. In most cases, these characteristic features are determined by their shell chemistry and morphology. Herein, we demonstrate a comparative study of silica and polydopamine (PDOP) coating onto MNP surfaces based on synthesis, characterization and usage in a bio-separation platform. It was found that monodispersed MNPs may be easily obtained on silica coating of varying shell thickness, whereas a continuous PDOP layer observed around the MNPs prevents the formation of the dispersed form. On the other hand, PDOP coated MNPs exhibited better superparamagnetic behavior and biological modification ability compared to the silica coated form. PMID:23050265

Sahin, Ferat; Turan, Eylem; Tumturk, Hayrettin; Demirel, Gokhan

2012-12-01

208

Nanomagnetism of Core-Shell Magnetic Nanoparticles and Application in Spent Nuclear Fuel Separation  

NASA Astrophysics Data System (ADS)

This dissertation presents the study on novel core-shell magnetic nanoparticles (NPs) with unique magnetic properties. Understanding the fundamental physics of antiferromagnetic - ferromagnetic interactions is essential to apply in different applications. Chromium (Cr) doped and undoped core-shell iron/iron-oxide NPs have been synthesized using cluster deposition system and studied with respect to their nanostructures, morphologies, sizes, chemical composition and magnetic properties. The room-temperature magnetic properties of Fe based NPs shows the strong dependence of intra/inter-particle interaction on NP size. The Cr-doped Fe NP shows the origin of sigma-FeCr phase at very low Cr concentration (2 at.%) unlike others reported at high Cr content and interaction reversal from dipolar to exchange interaction. A theoretical model of watermelon is constructed based on the experimental results and core-shell NP system in order to explain the physics of exchange interaction in Cr-doped Fe particles. The magnetic nanoparticle---chelator separation nanotechnology is investigated for spent nuclear fuel recycling and is reported 97% and 80% of extraction for Am(III) and Pu(IV) actinides respectively. If the long-term heat generating actinides such as Am(III) can be efficiently removed from the used fuel raffinates, the volume of material that can be placed in a given amount of repository space can be significantly increased. As it is a simple, versatile, compact, and cost efficient process that minimizes secondary waste and improves storage performance.

Tarsem Singh, Maninder Kaur

209

Isolation of primary mouse retinal ganglion cells using immunopanning-magnetic separation  

PubMed Central

Purpose To establish an effective system for isolating primary retinal ganglion cells (RGCs) from newborn mice. Methods The retinas were separated from enucleated eyeballs of Crl:CD-1 mice on postnatal day 1 to 4. RGCs were purified using three different methods, including two-step immunopanning (TSI), direct magnetic separation (DMS), and immunopanning-magnetic separation (IMS). Harvested cells were maintained for 24 h in a defined medium and then examined with immunocytochemistry, western immunoblotting, and real-time reverse transcription polymerase chain reaction (RT-PCR) for glial cell–specific glial fibrillary acidic protein (GFAP) and amacrine cell-specific syntaxin 1. Results As determined with immunofluorescence staining, RGCs purified by TSI were sparsely mixed with GFAP-positive astrocytes, and RGCs isolated by DMS were frequently mixed with syntaxin 1-positive amacrine cells. However, RGCs collected by IMS were seldom contaminated by GFAP-positive or syntaxin 1-positive cells. On western immunoblots, TSI cells showed significant GFAP expression, and DMS cells showed apparent syntaxin 1 expression, but IMS cells did not. Results of the real-time RT–PCR showed a similar tendency to those of the immunocytochemistry and western immunoblots. Conclusion Primary mouse RGCs were highly purified by the IMS method, combining the benefits of the TSI and DMS methods. This isolation method may provide a good experimental system for studying glaucoma in vitro. PMID:23233794

Iizuka, Yoko; Kim, Chan Yun; Seong, Gong Je

2012-01-01

210

Cocaine detection via rolling circle amplification of short DNA strand separated by magnetic beads.  

PubMed

A novel and sensitive fluorescence biosensor based on aptamer and rolling circle amplification for the determination of cocaine was developed in the present work. Here cocaine aptamers immobilized onto Au nanoparticles modified magnetic beads hybridized with short DNA strand. In the presence of cocaine, the short DNA strand was displaced from aptamer owing to cocaine specially binding with aptamer. Next, the short DNA strand was separated by magnetic beads and used to originate rolling circle amplification as primer. The end products of rolling circle amplification were detected by fluorescence signal generation upon molecular beacons hybridizing with the end products of rolling circle amplification. With rolling circle amplification and the separation by magnetic beads reducing the background signal, the new strategy was suitable for the detection of as low as 0.48 nM cocaine. Compared with reported cocaine sensors, our method exhibited excellent sensitivity. Our new strategy may provide a platform for numerous proteins and low molecular weight analytes to highly sensitively detect by DNA amplification. PMID:21277763

Ma, Cuiping; Wang, Wenshuo; Yang, Qing; Shi, Chao; Cao, Lijie

2011-03-15

211

Separation and measurement of silver nanoparticles and silver ions using magnetic particles.  

PubMed

The recent surge in consumer products and applications using metallic nanoparticles has increased the possibility of human or ecosystem exposure due to unintentional release into the environment. To protect consumer health and the environment, there is an urgent need to develop tools that can characterize and quantify these materials at low concentrations and in complex matrices. In this study, magnetic nanoparticles coated with either dopamine or glutathione were used to develop a new, simple and reliable method for the separation/pre-concentration of trace amounts of silver nanoparticles followed by their quantification using inductively coupled plasma mass spectrometry (ICP-MS). The structurally modified magnetic particles were able to capture trace amounts of silver nanoparticles (~2 ppb) and concentrate (up to 250 times) the particles for analysis with ICP-MS. Under laboratory conditions, recovery of silver nanoparticles was >99%. More importantly, the magnetic particles selectively captured silver nanoparticles in a mixture containing both nano-particulate and ionic silver. This unique feature addresses the challenges of separation and quantification of silver nanoparticles in addition to the total silver in environmental samples. Spiking experiments showed recoveries higher than 97% for tap water and both fresh and saline surface water. PMID:24295749

Mwilu, Samuel K; Siska, Emily; Baig, R B Nasir; Varma, Rajender S; Heithmar, Ed; Rogers, Kim R

2014-02-15

212

A THz Coaxial Two-Channel Dielectric Wakefield Structure for High Gradient Acceleration  

NASA Astrophysics Data System (ADS)

A coaxial two-channel dielectric wakefield structure is examined for use as a high gradient accelerator. A THz design, having radius ˜1 mm, is shown to provide GeV/m—level acceleration gradient, high transformer ratio, and stable accelerated bunch motion when excited by a stable-moving 5-GeV 6-nC annular drive bunch.

Marshall, T. C.; Sotnikov, G. V.; Hirshfield, J. L.

2010-11-01

213

Magnetic resonance assessment of iron overload by separate measurement of tissue ferritin and hemosiderin iron  

PubMed Central

With transfusional iron overload, almost all the excess iron is sequestered intracellularly as rapidly mobilizable, dispersed, soluble, ferritin iron, and as aggregated, insoluble hemosiderin iron for long-term storage. Established magnetic resonance imaging (MRI) indicators of tissue iron (R2, R2*) are principally influenced by hemosiderin iron and change slowly, even with intensive iron chelation. Intracellular ferritin iron is evidently in equilibrium with the low-molecular-weight cytosolic iron pool that can change rapidly with iron chelation. We have developed a new magnetic resonance imaging (MRI) method to separately measure ferritin and hemosiderin iron, based on the non-monoexponential signal decay induced by aggregated iron in multiple-spin-echo sequences. We have initially validated the method in agarose phantoms and in human liver explants and shown the feasibility of its application in patients with thalassemia major. Measurement of tissue ferritin iron is a promising new means to rapidly evaluate the effectiveness of iron-chelating regimens. PMID:20712781

Wu, Ed X.; Kim, Daniel; Tosti, Christina L.; Tang, Haiying; Jensen, Jens H.; Cheung, Jerry S.; Feng, Li; Au, Wing-Yan; Ha, Shau-Yin; Sheth, Sujit S.; Brown, Truman R.; Brittenham, Gary M.

2010-01-01

214

Chemical separation of primordial Li+ during structure formation caused by nanogauss magnetic field  

NASA Astrophysics Data System (ADS)

During the structure formation, charged and neutral chemical species may have separated from each other at the gravitational contraction in primordial magnetic field (PMF). A gradient in the PMF in a direction perpendicular to the field direction leads to the Lorentz force on the charged species. Resultantly, an ambipolar diffusion occurs, and charged species can move differently from neutral species, which collapses gravitationally during the structure formation. We assume a gravitational contraction of neutral matter in a spherically symmetric structure, and calculate fluid motions of charged and neutral species. It is shown that the charged fluid, i.e. proton, electron, and 7Li+, can significantly decouple from the neutral fluid depending on the field amplitude. The charged species can, therefore, escape from the gravitational collapse. We take the structure mass, the epoch of the gravitational collapse, and the comoving Lorenz force as parameters. We then identify a parameter region for an effective chemical separation. This type of chemical separation can reduce the abundance ratio of Li/H in early structures because of inefficient contraction of 7Li+ ion. Therefore, it may explain Li abundances of Galactic metal-poor stars which are smaller than the prediction in standard big bang nucleosynthesis model. Amplitudes of the PMFs are controlled by a magnetohydrodynamic turbulence. The upper limit on the field amplitude derived from the turbulence effect is close to the value required for the chemical separation.

Kusakabe, Motohiko; Kawasaki, Masahiro

2015-01-01

215

Method and apparatus for separating gases based on electrically and magnetically enhanced monolithic carbon fiber composite sorbents  

DOEpatents

A method for separating gases or other fluids involves placing a magnetic field on a monolithic carbon fiber composite sorption material to more preferentially attract certain gases or other fluids to the sorption material to which a magnetic field is applied. This technique may be combined with the known "pressure swing adsorption" technique utilizing the same sorption material.

Judkins, Roddie R. (9917 Rainbow Dr., Knoxville, TN 37922); Burchell, Timothy D. (109 Greywood Pl., Oak Ridge, TN 37830)

1999-01-01

216

IMPROVEMENT OF MAGNETICALLY SEPARATED FERROUS CONCENTRATE BY SHREDDING: A PERFORMANCE TEST. TEST NO. 4.07, RECOVERY 1, NEW ORLEANS  

EPA Science Inventory

This report describes a series of test runs in which ferrous product magnetically recovered from municipal waste was further shredded in a small (50 hp) hammermill to free attached or entrapped contaminant. A belt magnet was then used to separate metal from the liberated contamin...

217

Synthesis of teicoplanin-modified hybrid magnetic mesoporous silica nanoparticles and their application in chiral separation of racemic compounds.  

PubMed

Teicoplanin-conjugated mesoporous silica magnetic nanoparticles (TE-MSMNPs) were fabricated as novel chiral magnetic nano-selectors. Successful preparation of the functional magnetic mesoporous materials was achieved by grafting teicoplanin on N-(2-aminoethyl)-3-aminopropyltrimethoxysilane-modified mesoporous silica Fe3O4 magnetic nanoparticles (AEAPTMS-MSMNPs), and this was confirmed by various characterization techniques. The synthesized magnetic nanoparticles were regularly spherical and uniformly mesoporous with an average diameter of around 600 nm and a mean pore size of about 3.9 nm, respectively. These versatile magnetic nanoparticles were effective in a direct chiral separation of five racemic compounds in phosphate buffer. Much stronger interactions were observed with the (+)-enantiomers than with the (-)-enantiomers. After washing with water and ethanol by sonication, TE-MSMNPs could be reused at least three times with little efficiency loss. The functional magnetic mesoporous nanoparticles were easily separated from the racemic solutions using an external magnetic field. These magnetic nano-materials are suitable for enantiomer separations. PMID:23541694

Wu, Jingwei; Su, Ping; Huang, Jun; Wang, Siming; Yang, Yi

2013-06-01

218

Upgrading of PVC rich wastes by magnetic density separation and hyperspectral imaging quality control.  

PubMed

Polyvinylchloride (PVC) is one of the most produced polymers in Europe, with a share of 11% in terms of mass (8 milliontons) of total polymer consumption, but in 2010 only 5% of the total PVC production came from recycled materials, where other polymer recycling achieves a level of 15% on average. In order to find an innovative process to extract PVC from window frames waste, a combination of two innovative technologies was tested: magnetic density separation (MDS) and hyperspectral imaging (HSI). By its nature, MDS is a flexible high precision density separation technology that is applicable to any mixture of polymers and contaminants with non-overlapping densities. As PVC has a very distinctive high density, this technology was tested to obtain high-grade PVC pre-concentrates from window frame waste. HSI was used to perform a quality control of the products obtained by MDS showing that PVC was clearly discriminated from unwanted rubber particles of different colors. The results showed that the combined application of MDS and HSI techniques allowed to separate and to check the purity of PVC from window frame waste. PMID:25458764

Luciani, Valentina; Bonifazi, Giuseppe; Rem, Peter; Serranti, Silvia

2014-11-01

219

Temperature dependence of iron local magnetic moment in phase-separated superconducting chalcogenide  

NASA Astrophysics Data System (ADS)

We have studied local magnetic moment and electronic phase separation in superconducting KxFe2 -ySe2 by x-ray emission and absorption spectroscopy. Detailed temperature-dependent measurements at the Fe K-edge have revealed coexisting electronic phases and their correlation with the transport properties. By cooling down, the local magnetic moment of Fe shows a sharp drop across the superconducting transition temperature (Tc) and the coexisting phases exchange spectral weights with the low-spin state, gaining intensity at the expense of the higher-spin state. After annealing the sample across the iron-vacancy order temperature, the system does not recover the initial state and the spectral weight anomaly at Tc as well as superconductivity disappear. The results clearly underline that the coexistence of the low-spin and high-spin phases and the transitions between them provide unusual magnetic fluctuations and have a fundamental role in the superconducting mechanism of the electronically inhomogeneous KxFe2 -ySe2 system.

Simonelli, L.; Mizokawa, T.; Sala, M. Moretti; Takeya, H.; Mizuguchi, Y.; Takano, Y.; Garbarino, G.; Monaco, G.; Saini, N. L.

2014-12-01

220

Mass separation of a multi-component plasma flow travelling through a magnetic transport system  

NASA Astrophysics Data System (ADS)

The travel of plasma flow produced by a dc arc through a transport system based on a curved magnetic field was studied. The characteristics of the system were the absence of a curved metallic plasma guiding duct ('open architecture') and the fact that the magnetic field coils were non-coaxial to the plasma flow. By means of Langmuir probe measurements it was shown that both shape and position of the cathode plasma flow at the exit of the transport system were governed by variation of currents of the magnetic coils as well as by biasing of a special electrode inserted into the plasma flow. It was found that with parameters of the transport system held constant, the plasma ions with lower m/Z were deflected more, e.g. Al ions were deflected more than Ti ions. For an arc with a composite cathode, consisting of mainly Cr-Fe-Ni, the profile of atoms of these elements at the exit of the transport system was measured by x-ray fluorescence spectrometry. The results obtained were consistent with the probe measurements, hence the transport system, in principle, may be used for spatial separation of a multi-component (in masses) plasma flow.

Paperny, V. L.; Krasov, V. I.; Lebedev, N. V.; Astrakchantsev, N. V.

2011-06-01

221

Ultra-High Gradient S-Band Linac for Laboratory And Industrial Applications  

SciTech Connect

A strong demand for high gradient structures arises from the limited real estate available for linear accelerators. RadiaBeam Technologies is developing a Doubled Energy Compact Accelerator (DECA) structure: an S-band standing wave electron linac designed to operate at accelerating gradients of up to 50 MV/m. In this paper, we present the radio-frequency design of the DECA S-band accelerating structure, operating at 2.856 GHz in the {pi}-mode. The structure design is heavily influenced by NLC collaboration experience with ultra high gradient X-band structures; S-band, however, is chosen to take advantage of commonly available high power S-band klystrons.

Faillace, L.; /RadiaBeam Tech.; Agustsson, R.; /RadiaBeam Tech.; Dolgashev, V.; /SLAC; Frigola, P.; /RadiaBeam Tech.; Murokh, A.; /RadiaBeam Tech.; Rosenzweig, J.; /UCLA; Yakimenko, V.; /Brookhaven

2012-06-11

222

Ultra-High Gradient S-band Linac for Laboratory and Industrial Applications  

SciTech Connect

A strong demand for high gradient structures arises from the limited real estate available for linear accelerators. RadiaBeam Technologies is developing a Doubled Energy Compact Accelerator (DECA) structure: an S-band standing wave electron linac designed to operate at accelerating gradients of up to 50 MV/m. In this paper, we present the radio-frequency design of the DECA S-band accelerating structure, operating at 2.856 GHz in the {pi}-mode. The structure design is heavily influenced by NLC collaboration experience with ultra high gradient X-band structures; S-band, however, is chosen to take advantage of commonly available high power S-band klystrons.

Faillace, L.; Agustsson, R.; Frigola, P.; Murokh, A. [RadiaBeam Technologies, LLC., Santa Monica, CA 90404 (United States); Dolgashev, V. [Stanford Linear Accelerator Center, Menlo Park, CA 94025 (United States); Rosenzweig, J. [Department of Physics and Astronomy, University of California, Los Angeles, CA 90095 (United States); Yakimenko, V. [Brookhaven National Laboratory, Upton, NY 11973 (United States)

2010-11-04

223

Experimental and theoretical investigation of high gradient acceleration. Progress report, February 1, 1992--January 31, 1993  

SciTech Connect

This report contains a technical progress summary of the research conducted under the auspices of DOE Grant No. DE-AC02-91-ER40648, ``Experimental and Theoretical Investigations of High Gradient Acceleration``. This grant supports three research tasks: Task A consists of the design, fabrication and testing of a 17GHz RF photocathode gun, which can produce 2ps electron pulses with up to 1nC of charge at 2MeV energy and at a 1OHz repetition rate. Task B supports the testing of high gradient acceleration at 33GHz structure, and Task C comprises theoretical investigations, both in support of the experimental tasks and on critical physics issues for the development of high energy linear colliders.

Wurtele, J.S.; Bekefi, G.; Chen, C.; Chen, S.C.; Temkin, R.J.

1993-01-01

224

Exploring diffusion across permeable barriers at high gradients. II. Localization regime  

NASA Astrophysics Data System (ADS)

We present an analytical solution of the one-dimensional Bloch-Torrey equation for diffusion across multiple semi-permeable barrier. This solution generalizes the seminal work by Stoller, Happer, and Dyson, in which the non-Gaussian stretched-exponential behavior of the pulsed-gradient spin-echo (PGSE) signal was first predicted at high gradients in the so-called localization regime. We investigate how the diffusive exchange across a semi-permeable barrier modifies this asymptotic behavior, and explore the transition between the localization regime at low permeability and the Gaussian regime at high permeability. High gradients are suitable to spatially localize the contribution of the nuclei near the barrier and to enhance the sensitivity of the PGSE signal to the barrier permeability. The emergence of the localization regime for three-dimensional domains is discussed.

Grebenkov, Denis S.

2014-11-01

225

High-Gradient Operators in the psl(2|2) Gross-Neveu Model  

E-print Network

It has been observed more than 25 years ago that sigma model perturbation theory suffers from strongly RG-relevant high-gradient operators. The phenomenon was first seen in 1-loop calculations for the O(N) vector model and it is known to persist at least to two loops. More recently, Ryu et al. suggested that a certain deformation of the psl(N|N) WZNW-model at level k = 1, or equivalently the psl(N|N) Gross-Neveu model, could be free of RG-relevant high-gradient operators and they tested their suggestion to leading order in perturbation theory. In this note we establish the absence of strongly RG-relevant high-gradient operators in the psl(2|2) Gross-Neveu model to all loops. In addition, we determine the spectrum for a large subsector of the model at infinite coupling and observe that all scaling weights become half-integer. Evidence for a conjectured relation with the CP^1|2 sigma model is not found.

Cagnazzo, Alessandra; Tlapák, Václav

2014-01-01

226

Separation of semiconducting and ferromagnetic FeSi2-nanoparticles by magnetic filtering  

NASA Astrophysics Data System (ADS)

We have investigated the potential of solution-processed ?-phase iron disilicide (FeSi2) nanoparticles as a novel semiconducting material for photovoltaic applications. Combined ultraviolet-visible absorption and photothermal deflection spectroscopy measurements have revealed a direct band gap of 0.85 eV and, therefore, a particularly high absorption in the near infrared. With the help of Fourier-transform infrared and X-ray photoelectron spectroscopy, we have observed that exposure to air primarily leads to the formation of a silicon oxide rather than iron oxide. Mössbauer measurements have confirmed that the nanoparticles possess a phase purity of more than 99%. To diminish the small fraction of metallic iron impurities, which were detected by superconducting quantum interference device magnetometry and which would act as unwanted Auger recombination centers, we present a novel concept to magnetically separate the FeSi2 nanoparticles (NPs). This process leads to a reduction of more than 95% of the iron impurities.

Aigner, Willi; Niesar, Sabrina; Mehmedovic, Ervin; Opel, Matthias; Wagner, Friedrich E.; Wiggers, Hartmut; Stutzmann, Martin

2013-10-01

227

Control of separated flow in a reflected shock interaction using a magnetically-accelerated surface discharge  

NASA Astrophysics Data System (ADS)

A numerical investigation was carried out to explore the effects of a magnetically-accelerated surface discharge on a separated, turbulent boundary layer in supersonic flow. The geometry and test conditions were chosen for comparison to experiments carried out at Princeton University. For those studies, a reflected shock interaction was created using a 14° shock generator acting on an incoming turbulent boundary layer with a Reynolds number based on momentum thickness of 1 × 104 and a freestream Mach number of 2.6. Three-dimensional, Reynolds-averaged, Navier-Stokes (RANS) calculations were carried out to simulate the experiments, using the US3D code developed at the University of Minnesota. The baseline code was modified to include a semi-empirical model of the surface discharge actuator, implemented through source terms in the momentum equation, vibrational energy equation, and total energy equation. The computational results for the baseline flow and several control cases were compared to experimental measurements of mean surface pressure. The level of discrepancy was typical of well-resolved RANS computations of three-dimensional, separated flows: qualitative agreement was obtained, and the general experimental trends were captured by the numerical model. Substantial three-dimensionality was observed even in the baseline flow, and significant changes in the flow topology were observed with the application of the actuator. Because of the highly three-dimensional nature of this shock interaction, the initial interpretation of the experiments may need to be revisited.

Atkinson, Michael D.; Poggie, Jonathan; Camberos, José A.

2012-12-01

228

Multi-MW K-Band Harmonic Multiplier: RF Source For High-Gradient Accelerator R & D  

NASA Astrophysics Data System (ADS)

A preliminary design is presented for a two-cavity harmonic multiplier, intended as a high-power RF source for use in experiments aimed at developing high-gradient structures for a future collider. The harmonic multiplier is to produce power at selected frequencies in K-band (18-26.5 GHz) using as an RF driver an XK-5 S-band klystron (2.856 GHz). The device is to be built with a TE111 rotating mode input cavity and interchangeable output cavities running in the TEn11 rotating mode, with n = 7,8,9 at 19.992, 22.848, and 25.704 GHz. An example for a 7th harmonic multiplier is described, using a 250 kV, 20 A injected laminar electron beam; with 10 MW of S-band drive power, 4.7 MW of 20-GHz output power is predicted. Details are described of the magnetic circuit, cavities, and output coupler.

Solyak, N. A.; Yakovlev, V. P.; Kazakov, S. Yu.; Hirshfield, J. L.

2009-01-01

229

Multi-MW K-Band 7th Harmonic Multiplier for High-Gradient Accelerator R&D  

SciTech Connect

A preliminary design and current status are presented for a two-cavity 7th harmonic multiplier, intended as a high-power RF source for use in experiments aimed at developing high-gradient structures for a future collider. The harmonic multiplier is to produce power in K-band using as its RF driver an XK-5 S-band klystron (2.856 GHz). The multiplier is to be built with a TE{sub 111} rotating mode input cavity and interchangeable output cavities, a principal example being a TE{sub 711} rotating mode cavity running at 20 GHz. The design that is described uses a 250 kV, 20 A injected laminar electron beam. With 8.5 MW of S-band drive power, 4.4 MW of 20-GHz output power is predicted. The design uses a gun, magnetic coils, and beam collector from an existing waveguide 7th harmonic multiplier. The gun has been re-conditioned and the desired operating parameters have been achieved.

Solyak, N.A.; Yakovlev, V.P.; /Omega-P, New Haven /Fermilab; Hirschfield, J.L.; /Omega-P, New Haven /Yale U.; Kazakevich, G.M.; /Omega-P, New Haven; LaPointe, M.A.; /Yale U.

2009-05-01

230

Juwen and High Gradient Structure Development From SLAC's SLC to NLC/GLC  

NASA Astrophysics Data System (ADS)

A Global Effort -- The effort to develop high gradient room temperature accelerator structures for the Next Linear Collider or the Global Linear Collider was a global effort involving many people from a number of laboratories around the world including SLAC, FNAL and LLNL in the US, KEK in Japan and CERN in Europe. Critical ideas came from many sources, so my attributions may not always be accurate, but indicate where I first heard the concept. Juwen Wang's role was very important in accepting, modifying where appropriate, and implementing ideas to produce a long series of structures finally leading to a successful structure.

Miller, R. H.

2015-10-01

231

Fabrication of anisotropic porous silica monoliths by means of magnetically controlled phase separation in sol-gel processes.  

PubMed

Sol-gel accompanied by phase separation is an established method for the preparation of porous silica monoliths with well-defined macroporosity, which find numerous applications. In this work, we demonstrate how the addition of (superpara)magnetic nanocolloids as templates to a system undergoing a sol-gel transition with phase separation leads to the creation of monoliths with a strongly anisotropic structure. It is known that magnetic nanocolloids respond to the application of an external magnetic field by self-assembling into columnar structures. The application of a magnetic field during the chemically driven spinodal decomposition induced by the sol-gel transition allows one to break the symmetry of the system and promote the growth of elongated needle-like silica domains incorporating the magnetic nanocolloids, aligned in the direction of the field. It is found that this microstructure imparts a strong mechanical anisotropy to the materials, with a ratio between the Young's modulus values measured in a direction parallel and perpendicular to the one of the field as high as 150, and an overall smaller average macropores size as compared to isotropic monoliths. The microstructure and properties of the porous monoliths can be controlled by changing both the system composition and the strength of the applied magnetic field. Our monoliths represent the first example of materials prepared by magnetically controlling a phase transition occurring via spinodal decomposition. PMID:22849804

Furlan, Marco; Lattuada, Marco

2012-08-28

232

In situ magnetic separation of antibody fragments from Escherichia coli in complex media  

PubMed Central

Background In situ magnetic separation (ISMS) has emerged as a powerful tool to overcome process constraints such as product degradation or inhibition of target production. In the present work, an integrated ISMS process was established for the production of his-tagged single chain fragment variable (scFv) D1.3 antibodies (“D1.3”) produced by E. coli in complex media. This study investigates the impact of ISMS on the overall product yield as well as its biocompatibility with the bioprocess when metal-chelate and triazine-functionalized magnetic beads were used. Results Both particle systems are well suited for separation of D1.3 during cultivation. While the triazine beads did not negatively impact the bioprocess, the application of metal-chelate particles caused leakage of divalent copper ions in the medium. After the ISMS step, elevated copper concentrations above 120 mg/L in the medium negatively influenced D1.3 production. Due to the stable nature of the model protein scFv D1.3 in the biosuspension, the application of ISMS could not increase the overall D1.3 yield as was shown by simulation and experiments. Conclusions We could demonstrate that triazine-functionalized beads are a suitable low-cost alternative to selectively adsorb D1.3 fragments, and measured maximum loads of 0.08 g D1.3 per g of beads. Although copper-loaded metal-chelate beads did adsorb his-tagged D1.3 well during cultivation, this particle system must be optimized by minimizing metal leakage from the beads in order to avoid negative inhibitory effects on growth of the microorganisms and target production. Hereby, other types of metal chelate complexes should be tested to demonstrate biocompatibility. Such optimized particle systems can be regarded as ISMS platform technology, especially for the production of antibodies and their fragments with low stability in the medium. The proposed model can be applied to design future ISMS experiments in order to maximize the overall product yield while the amount of particles being used is minimized as well as the number of required ISMS steps. PMID:23688064

2013-01-01

233

Beam-Energy Dependence of Charge Separation Along the Magnetic Field in Au + Au Collisions at RHIC  

E-print Network

Local parity-odd domains are theorized to form inside a quark-gluon plasma which has been produced in high-energy heavy-ion collisions. The local parity-odd domains manifest themselves as charge separation along the magnetic ...

Stevens, Justin

234

MAGNETIC DRUM SEPARATOR PERFORMANCE SCALPING TROMMEL UNDERFLOW AT NOMINAL DESIGN CONDITIONS. TEST NO. 4.01, RECOVERY 1, NEW ORLEANS  

EPA Science Inventory

This report describes the first test of the magnetic drum separator that was designed to scalp the underflow of the trommel, or rotary screen, at the New Orleans, Louisiana, resource recovery facility. The objective of the test was to document the performance of the trommel-under...

235

Magnetically separable nanocomposites with photocatalytic activity under visible light for the selective transformation of biomass-derived platform molecules  

EPA Science Inventory

Novel magnetically separable TiO2-guanidine-(Ni,Co)Fe2O4 nanomaterials were prepared and characterised by a series of techniques including XRD, SEM, TEM, N2 physisorption as well as XPS and subsequently tested for their photocatalytic activities in the selective transformation of...

236

Environmental friendly crush-magnetic separation technology for recycling metal-plated plastics from end-of-life vehicles.  

PubMed

Metal-plated plastics (MPP), which are important from the standpoint of aesthetics or even performance, are increasingly employed in a wide variety of situations in the automotive industry. Serious environmental problems will be caused if they are not treated appropriately. Therefore, recycling of MPP is an important subject not only for resource recycling but also for environmental protection. This work represents a novel attempt to deal with the MPP. A self-designed hammer crusher was used to liberate coatings from the plastic substrate. The size distribution of particles was analyzed and described by the Rosin-Rammler function model. The optimum retaining time of materials in the crusher is 3 min. By this time, the liberation rate of the materials can reach 87.3%. When the density of the suspension is 31,250 g/m(3), the performance of liberation is the best. Two-step magnetic separation was adopted to avoid excessive crushing and to guarantee the quality of products. Concerning both the separation efficiency and grade of products, the optimum rotational speed of the magnetic separator is 50-70 rpm. On the basis of the above studies about the liberating and separating behavior of the materials, a continuous recycling system (the technology of crush-magnetic separation) is developed. This recycling system provides a feasible method for recycling MPP efficiently, economically, and environmentally. PMID:22304328

Xue, Mianqiang; Li, Jia; Xu, Zhenming

2012-03-01

237

Relativistic klystron driven compact high gradient accelerator as an injector to an X-ray synchrotron radiation ring  

DOEpatents

A compact high gradient accelerator driven by a relativistic klystron is utilized to inject high energy electrons into an X-ray synchrotron radiation ring. The high gradients provided by the relativistic klystron enables accelerator structure to be much shorter (typically 3 meters) than conventional injectors. This in turn enables manufacturers which utilize high energy, high intensity X-rays to produce various devices, such as computer chips, to do so on a cost effective basis.

Yu, David U. L. (1912 MacArthur St., Rancho Palos Verdes, CA 90732)

1990-01-01

238

Ferrimagnetism and magnetic phase separation in Nd1-xYxMnO3 studied by magnetization and high frequency electron paramagnetic resonance  

NASA Astrophysics Data System (ADS)

Ferrimagnetism and metamagnetic features tunable by composition are observed in the magnetic response of Nd1-xYxMnO3, for x=0.1-0.5. For all values of x in the series, the compound crystallizes in orthorhombic Pbnm space group similar to NdMnO3. Magnetization studies reveal a phase transition of the Mn-sublattice below T N Mn ? 80 K for all compositions, which, decreases up on diluting the Nd-site with Yttrium. For x=0.35, ferrimagnetism is observed. At 5 K, metamagnetic transition is observed for all compositions x < 0.4. The evolution of magnetic ground states and appearance of ferrimagnetism in Nd1-xYxMnO3 can be accounted for by invoking the scenario of magnetic phase separation. The high frequency electron paramagnetic resonance measurements on x=0.4 sample, which is close to the critical composition for phase separation, revealed complex temperature dependent lineshapes clearly supporting the assumption of magnetic phase separation.

Nair, Harikrishnan S.; Yadav, Ruchika; Adiga, Shilpa; Rao, S. S.; van Tol, Johan; Elizabeth, Suja

2015-01-01

239

Separation of Sudan dyes from chilli powder by magnetic molecularly imprinted polymer.  

PubMed

A simple method based on magnetic molecularly imprinted polymers (MMIPs) for the separation of Sudan dyes from chilli powder samples has been developed. The MMIPs were synthesized as follows: the Fe(3)O(4) nanoparticles were encapsulated with a SiO(2) shell and functionalized with -CH=CH(2), then the polymers were further fabricated by surface-imprinted polymerization using Sudan IV as template molecule, methacrylic acid as functional monomer, and ethylene glycol dimethacrylate as cross-linking agent. The prepared MMIPs were characterized by scanning electron microscope, Fourier transform infrared spectrometry and physical property measurement system. The isothermal absorption experiment, kinetics absorption experiment and selectivity of MMIPs were tested. The analytes were determined by high performance liquid chromatography. Under the optimal conditions, the limits of detection of the four Sudan dyes are 6.2, 1.6, 4.3 and 4.5 ng g(-1), respectively. The precision expressed as relative standard deviation ranging from 4.8% to 9.1% was obtained. In all three fortified levels (25, 250 and 2500 ng g(-1)), recoveries of Sudan dyes were in the range of 79.9-87.8%. PMID:23141623

Piao, Chunying; Chen, Ligang

2012-12-14

240

Magnetic counter-gravity flow separation of electrically prepolarised lymphoid cells.  

PubMed

A novel principle is proposed for a differential separation of live cells (such as leucocytes) from a main flow. A microfluidic device with planar insulated electrodes as the side walls of the channel was manufactured and tested. An array of insulated vertical conductor wires was inserted along the axis of the channel and used to impose Lorentz forces upon polarisable particles that moved with the flow. Polystyrene microspheres and lymphoid cell lines (DOHH2 and K562) were used to test the ability of the setting to impose a force field that induced consistent vertical motion. The direction of electric current was found to directly influence the number of cells or microspheres that were sampled at the surface of the flow. Lorentz force was considered to be active upon cells due to an overall polarisation of the membrane surface. The consequence of the magnetic force was that the polarised cells were moved vertically upwards (opposing gravity). The setting was effective for increasing the number of extracted cells from a main flow or for increasing the concentration of DOHH2 cells in a mixed population with K562 in culture medium. The limitations of the work parameters (potential-current) were found to be dependent upon the cell type. PMID:17278260

Popa, C; Su, B; Vadgama, P; Cotter, F

2007-02-01

241

The synthesis, characterization and application of iron oxide nanocrystals in magnetic separations for arsenic and uranium removal  

NASA Astrophysics Data System (ADS)

Arsenic and uranium in the environment are hazardous to human health and require better methods for detection and remediation. Nanocrystalline iron oxides offer a number of advantages as sorbents for water purification and environmental remediation. First, highly uniform and crystalline iron oxide nanocrystals (nMAG) were prepared using thermal decomposition of iron salts in organic solutions; for the applications of interest in this thesis, a central challenge was the adaptation of these conventional synthetic methods to the needs of low infrastructure and economically disadvantaged settings. We show here that it is possible to form highly uniform and magnetically responsive nanomaterials using starting reagents and equipment that are readily available and economical. The products of this approach, termed the 'Kitchen Synthesis', are of comparable quality and effectiveness to laboratory materials. The narrow size distributions of the iron oxides produced in the laboratory synthesis made it possible to study the size-dependence of the magnetic separation efficiency of nanocrystals; generally as the diameter of particles increased they could be removed under lower applied magnetic fields. In this work we take advantage of this size-dependence to use magnetic separation as a tool to separate broadly distributed populations of magnetic materials. Such work makes it possible to use these materials in multiplexed separation and sensing schemes. With the synthesis and magnetic separation studies of these materials completed, it was possible to optimize their applications in water purification and environmental remediation. These materials removed both uranium and arsenic from contaminated samples, and had remarkably high sorption capacities --- up to 12 wt% for arsenic and 30 wt% for uranium. The contaminated nMAG is removed from the drinking water by either retention in a sand column, filter, or by magnetic separation. The uranium adsorption process was also utilized for the enhanced detection of uranium in environmental matrices. By relying on alpha-particle detection in well-formed and dense nMAG films, it was possible to improve soil detection of uranium by more than ten-thousand-fold. Central for this work was a detailed understanding of the chemistry at the iron oxide interface, and the role of the organic coatings in mediating the sorption process.

Mayo, John Thomas

242

Utility of Magnetic Cell Separation as a Molecular Sperm Preparation Technique  

PubMed Central

Assisted reproductive techniques (ART) have become the treatment of choice in many cases of infertility; however the current success rates of these procedures remain suboptimal. Programmed cell death (apoptosis) most likely contributes to failed ART and to the decrease in sperm quality after cryopreservation. There is likelihood that some sperm selected for ART will display features of apoptosis despite their normal appearance, which may be partially responsible for the low fertilization and implantation rates seen with ART. One of the features of apoptosis is the externalization of phosphatidylserine (PS) residues, which are normally present on the inner leaflet of the sperm plasma membrane. Colloidal super-paramagnetic microbeads (~50 nm in diameter) conjugated with annexin-V bind to PS are used to separate dead and apoptotic spermatozoa by magnetic cell sorting (MACS). Cells with externalized PS will bind to these microbeads, while non-apoptotic cells with intact membranes do not bind and could be used during ART. We have conducted a series of experiments to investigate if the MACS technology could be used to improve ART outcomes. Our results clearly indicate that integrating MACS as a part of sperm preparation techniques will improve semen quality and cryosurvival rates by eliminating apoptotic sperm. Non-apoptotic spermatozoa prepared by MACS display higher quality in terms of routine sperm parameters and apoptosis markers. The higher sperm quality is represented by an increased oocyte penetration potential and cryosurvival rates. Thus, the selection of non-apoptotic spermatozoa by MACS should be considered to enhance ART success rates. PMID:18077822

Said, Tamer M.; Agarwal, Ashok; Zborowski, Maciej; Grunewald, Sonja; Glander, Hans-Juergen; Paasch, Uwe

2009-01-01

243

Dense Plasma Focus Z-pinches for High Gradient Particle Acceleration  

SciTech Connect

The final Z-pinch stage of a Dense Plasma Focus (DPF) could be used as a simple, compact, and potentially rugged plasma-based high-gradient accelerator with fields at the 100 MV/m level. In this paper we review previously published experimental beam data that indicate the feasibility of such an DPF-based accelerator, qualitatively discuss the physical acceleration processes in terms of the induced voltages, and as a starting point examine the DPF acceleration potential by numerically applying a self-consistent DPF system model that includes the induced voltage from both macroscopic and instability driven plasma dynamics. Applications to the remote detection of high explosives and a multi-staged acceleration concept are briefly discussed.

Tang, V; Adams, M L; Rusnak, B

2009-07-24

244

HIGH-GRADIENT, HIGH-TRANSFORMER-RATIO, DIELECTRIC WAKE FIELD ACCELERATOR  

SciTech Connect

The Phase I work reported here responds to DoE'ss stated need "...to develop improved accelerator designs that can provide very high gradient (>200 MV/m for electrons...) acceleration of intense bunches of particles." Omega-P'�s approach to this goal is through use of a ramped train of annular electron bunches to drive a coaxial dielectric wakefield accelerator (CDWA) structure. This approach is a direct extension of the CDWA concept from acceleration in wake fields caused by a single drive bunch, to the more efficient acceleration that we predict can be realized from a tailored (or ramped) train of several drive bunches. This is possible because of a much higher transformer ratio for the latter. The CDWA structure itself has a number of unique features, including: a high accelerating gradient G, potentially with G > 1 GeV/m; continuous energy coupling from drive to test bunches without transfer structures; inherent transverse focusing forces for particles in the accelerated bunch; highly stable motion of high charge annular drive bunches; acceptable alignment tolerances for a multi-section system. What is new in the present approach is that the coaxial dielectric structure is now to be energized by-not one-�but by a short train of ramped annular-shaped drive bunches moving in the outer coaxial channel of the structure. We have shown that this allows acceleration of an electron bunch traveling along the axis in the inner channel with a markedly higher transformer ratio T than for a single drive bunch. As described in this report, the structure will be a GHz-scale prototype with cm-scale transverse dimensions that is expected to confirm principles that can be applied to the design of a future THz-scale high gradient (> 500 MV/m) accelerator with mm-scale transverse dimensions. We show here a new means to significantly increase the transformer ratio T of the device, and thereby to significantly improve its suitability as a flexible and effective component in a future high energy, high gradient accelerator facility. We predict that the T of a high gradient CDWA can be increased by a substantial factor; this enhancement is dramatically greater than what has been demonstrated heretofore. This large enhancement in T that we predict arises from using a train of three or four drive bunches in which the spacing of the bunches and their respective charges are selected according to a simple principle that requires each bunch lose energy to the wakefields at the same rate, so as not to sacrifice drive beam efficiency�¢����as would be the case if one bunch exhausted its available energy while others had not. It is anticipated that results from the study proposed here can have a direct impact on design of the dielectric accelerator in a TeV-scale collider concept, and in the accelerator for an x-ray FEL.

Jay L. Hirshfield

2012-04-12

245

Fabrication Technologies of the High Gradient Accelerator Structures at 100MV/M Range  

SciTech Connect

A CERN-SLAC-KEK collaboration on high gradient X-band structure research has been established in order to demonstrate the feasibility of the CLIC baseline design for the main linac stably operating at more than 100 MV/m loaded accelerating gradient. Several prototype CLIC structures were successfully fabricated and high power tested. They operated at 105 MV/m with a breakdown rate that meets the CLIC linear collider specifications of < 5 x 10{sup -7}/pulse/m. This paper summarizes the fabrication technologies including the mechanical design, precision machining, chemical cleaning, diffusion bonding as well as vacuum baking and all related assembly technologies. Also, the tolerances control, tuning and RF characterization will be discussed.

Wang, Juwen; /SLAC; Lewandowski, James; /SLAC; Van Pelt, John; /SLAC; Yoneda, Charles; /SLAC; Gudkov, Boris; /CERN; Riddone, Germana; /CERN; Higo, Toshiyasu; /KEK, Tsukuba; Takatomi, Toshikazu; /KEK, Tsukuba

2012-07-03

246

Free-electron laser as a power source for a high-gradient accelerating structure  

SciTech Connect

A two beam colliding linac accelerator is proposed in which one beam is intense (approx. = 1KA), of low energy (approx. = MeV), and long (approx. = 100 ns) and provides power at 1 cm wavelength through a free-electron-laser-mechanism to the second beam of a few electrons (approx. = 10/sup 11/), which gain energy at the rate of 250 MeV/m in a high-gradient accelerating structure and hence reach 375 GeV in 1.5 km. The intense beam is given energy by induction units and gains, and losses by radiation, 250 keV/m thus supplying 25 J/m to the accelerating structure. The luminosity, L, of two such linacs would be, at a repetition rate of 1 kHz, L = 4. x 10/sup 32/ cm/sup -2/ s/sup -1/.

Sessler, A.M.

1982-02-01

247

Ultra-High Gradient Compact S-Band Linac for Laboratory and Industrial Applications  

SciTech Connect

There is growing demand from the industrial and research communities for high gradient, compact RF accelerating structures. The commonly used S-band SLAC-type structure has an operating gradient of only about 20 MV/m; while much higher operating gradients (up to 70 MV/m) have been recently achieved in X-band, as a consequence of the substantial efforts by the Next Linear Collider (NLC) collaboration to push the performance envelope of RF structures towards higher accelerating gradients. Currently however, high power X-band RF sources are not readily available for industrial applications. Therefore, RadiaBeam Technologies is developing a short, standing wave S-band structure which uses frequency scaled NLC design concepts to achieve up to a 50 MV/m operating gradient at 2856 MHz. The design and prototype commissioning plans are presented.

Faillace, Luigi; /RadiaBeam Tech.; Agustsson, Ronald; /RadiaBeam Tech.; Frigola, Pedro; /RadiaBeam Tech.; Murokh, Alex; /RadiaBeam Tech.; Dolgashev, Valery; /SLAC; Rosenzweig, James; /UCLA

2012-07-03

248

Ion Solid Interaction And Surface Modification At RF Breakdown In High-Gradient Linacs  

SciTech Connect

Ion solid interactions have been shown to be an important new mechanism of unipolar arc formation in high-gradient rf linear accelerators through surface self-sputtering by plasma ions, in addition to an intense surface field evaporation. We believe a non-Debye plasma is formed in close vicinity to the surface and strongly affects surface atomic migration via intense bombardment by ions, strong electric field, and high surface temperature. Scanning electron microscope studies of copper surface of an rf cavity were conducted that show craters, arc pits, and both irregular and regular ripple structures with a characteristic length of 2 microns on the surface. Strong field enhancements are characteristic of the edges, corners, and crack systems at surfaces subjected to rf breakdown.

Insepov, Zeke; Norem, Jim [Argonne National Laboratory, 9700 South Cass Avenue, Argonne, IL 60439 (United States); Veitzer, Seth [Tech-X Corp., 5621 Arapahoe Ave., Suite A, Boulder CO 80303 (United States)

2011-06-01

249

Towards an electro-magnetic field separation of deposited material implemented in an ion beam sputter process  

SciTech Connect

Nowadays, Ion Beam Sputter (IBS) processes are very well optimized on an empirical basis. To achieve further progresses, a modification of the IBS process by guiding the coating material using an axial magnetic field and an additional electrical field has been studied. The electro-magnetic (EM) field leads to a significant change in plasma properties and deposition rate distributions, whereas an increase in deposition rate along the centerline of the axial EM field around 150% was observed. These fundamental studies on the prototype are the basis for the development of an applicable and workable design of a separation device.

Malobabic, Sina; Jupe, Marco; Ristau, Detlev [Laser Component Department, Laser Zentrum Hannover e.V., Hollerithallee 8, 30149 Hannover (Germany) [Laser Component Department, Laser Zentrum Hannover e.V., Hollerithallee 8, 30149 Hannover (Germany); Quest: Centre of Quantum Engineering and Space-Time Research, Leibniz Universitaet Hannover, Hannover (Germany)

2013-06-03

250

Two Alternate High Gradient Quadrupoles; An Upgraded Tevatron IR and A"Pipe" Design  

SciTech Connect

With the U.S. cancellation of the SSC project, the only large approved hadron accelerator project is CERN's LHC. One of the more critical elements in the performance of a collider is the quadrupole lens at the beam collision points. These quadrupoles, usually referred to as the 'insertion quads' normally form a set of triplets around the interaction region. Their focal power directly affects the luminosity available at the crossing point In order to achieve as high a gradient as possible, the CERN design team has proposed a very efficient high gradient quadrupole which is based on a graded four-layer winding structure. At Fermilab's Tevatron, an upgraded two layer winding quadrupole has been in operation since 1989, and has provided a 50% higher gradient than its predecessor. The quadrupole was basically state of the art when it was designed in 1985. Since then however, improvements have been made in cabling, conductor perfonnance, etc. Naturally, operation of a modernized version of this .design can provide higher capabilities. This improved two layer design can serve as an alternative to the more intricate graded four layer design now envisioned for the LHC, provided it can obtain the proposed gradient. A high gradient quadrupole with a 'pipe' layout can be considered as a possible candidate for future large collider insertion regions. It is possible to fine-tune the design to obtain a good field-quality, the conductor is well cooled in case of a large radiation heat load, and the overall structure is smaller than a conventional quadrupole with a comparable field gradient.

McInturff, A.D.; Oort, J.M. van; Scanlan, R.M.

1995-04-01

251

Beam-energy dependence of charge separation along the magnetic field in Au+Au collisions at RHIC  

E-print Network

Local parity-odd domains are theorized to form inside a Quark-Gluon-Plasma (QGP) which has been produced in high-energy heavy-ion collisions. The local parity-odd domains manifest themselves as charge separation along the magnetic field axis via the chiral magnetic effect (CME). The experimental observation of charge separation has previously been reported for heavy-ion collisions at the top RHIC energies. In this paper, we present the results of the beam-energy dependence of the charge correlations in Au+Au collisions at midrapidity for center-of-mass energies of 7.7, 11.5, 19.6, 27, 39 and 62.4 GeV from the STAR experiment. After background subtraction, the signal gradually reduces with decreased beam energy, and tends to vanish by 7.7 GeV. The implications of these results for the CME will be discussed.

STAR Collaboration; L. Adamczyk; J. K. Adkins; G. Agakishiev; M. M. Aggarwal; Z. Ahammed; I. Alekseev; J. Alford; C. D. Anson; A. Aparin; D. Arkhipkin; E. C. Aschenauer; G. S. Averichev; A. Banerjee; D. R. Beavis; R. Bellwied; A. Bhasin; A. K. Bhati; P. Bhattarai; H. Bichsel; J. Bielcik; J. Bielcikova; L. C. Bland; I. G. Bordyuzhin; W. Borowski; J. Bouchet; A. V. Brandin; S. G. Brovko; S. Bültmann; I. Bunzarov; T. P. Burton; J. Butterworth; H. Caines; M. Calderón de la Barca Sánchez; D. Cebra; R. Cendejas; M. C. Cervantes; P. Chaloupka; Z. Chang; S. Chattopadhyay; H. F. Chen; J. H. Chen; L. Chen; J. Cheng; M. Cherney; A. Chikanian; W. Christie; J. Chwastowski; M. J. M. Codrington; G. Contin; J. G. Cramer; H. J. Crawford; X. Cui; S. Das; A. Davila Leyva; L. C. De Silva; R. R. Debbe; T. G. Dedovich; J. Deng; A. A. Derevschikov; R. Derradi de Souza; S. Dhamija; B. di Ruzza; L. Didenko; C. Dilks; F. Ding; P. Djawotho; X. Dong; J. L. Drachenberg; J. E. Draper; C. M. Du; L. E. Dunkelberger; J. C. Dunlop; L. G. Efimov; J. Engelage; K. S. Engle; G. Eppley; L. Eun; O. Evdokimov; O. Eyser; R. Fatemi; S. Fazio; J. Fedorisin; P. Filip; E. Finch; Y. Fisyak; C. E. Flores; C. A. Gagliardi; D. R. Gangadharan; D. Garand; F. Geurts; A. Gibson; M. Girard; S. Gliske; L. Greiner; D. Grosnick; D. S. Gunarathne; Y. Guo; A. Gupta; S. Gupta; W. Guryn; B. Haag; A. Hamed; L-X. Han; R. Haque; J. W. Harris; S. Heppelmann; A. Hirsch; G. W. Hoffmann; D. J. Hofman; S. Horvat; B. Huang; H. Z. Huang; X. Huang; P. Huck; T. J. Humanic; G. Igo; W. W. Jacobs; H. Jang; E. G. Judd; S. Kabana; D. Kalinkin; K. Kang; K. Kauder; H. W. Ke; D. Keane; A. Kechechyan; A. Kesich; Z. H. Khan; D. P. Kikola; I. Kisel; A. Kisiel; D. D. Koetke; T. Kollegger; J. Konzer; I. Koralt; L. K. Kosarzewski; L. Kotchenda; A. F. Kraishan; P. Kravtsov; K. Krueger; I. Kulakov; L. Kumar; R. A. Kycia; M. A. C. Lamont; J. M. Landgraf; K. D. Landry; J. Lauret; A. Lebedev; R. Lednicky; J. H. Lee; M. J. LeVine; C. Li; W. Li; X. Li; X. Li; Y. Li; Z. M. Li; M. A. Lisa; F. Liu; T. Ljubicic; W. J. Llope; M. Lomnitz; R. S. Longacre; X. Luo; G. L. Ma; Y. G. Ma; D. M. M. D. Madagodagettige Don; D. P. Mahapatra; R. Majka; S. Margetis; C. Markert; H. Masui; H. S. Matis; D. McDonald; T. S. McShane; N. G. Minaev; S. Mioduszewski; B. Mohanty; M. M. Mondal; D. A. Morozov; M. K. Mustafa; B. K. Nandi; Md. Nasim; T. K. Nayak; J. M. Nelson; G. Nigmatkulov; L. V. Nogach; S. Y. Noh; J. Novak; S. B. Nurushev; G. Odyniec; A. Ogawa; K. Oh; A. Ohlson; V. Okorokov; E. W. Oldag; D. L. Olvitt Jr.; M. Pachr; B. S. Page; S. K. Pal; Y. X. Pan; Y. Pandit; Y. Panebratsev; T. Pawlak; B. Pawlik; H. Pei; C. Perkins; W. Peryt; P. Pile; M. Planinic; J. Pluta; N. Poljak; K. Poniatowska; J. Porter; A. M. Poskanzer; N. K. Pruthi; M. Przybycien; P. R. Pujahari; J. Putschke; H. Qiu; A. Quintero; S. Ramachandran; R. Raniwala; S. Raniwala; R. L. Ray; C. K. Riley; H. G. Ritter; J. B. Roberts; O. V. Rogachevskiy; J. L. Romero; J. F. Ross; A. Roy; L. Ruan; J. Rusnak; O. Rusnakova; N. R. Sahoo; P. K. Sahu; I. Sakrejda; S. Salur; J. Sandweiss; E. Sangaline; A. Sarkar; J. Schambach; R. P. Scharenberg; A. M. Schmah; W. B. Schmidke; N. Schmitz; J. Seger; P. Seyboth; N. Shah; E. Shahaliev; P. V. Shanmuganathan; M. Shao; B. Sharma; W. Q. Shen; S. S. Shi; Q. Y. Shou; E. P. Sichtermann; R. N. Singaraju; M. J. Skoby; D. Smirnov; N. Smirnov; D. Solanki; P. Sorensen; H. M. Spinka; B. Srivastava; T. D. S. Stanislaus; J. R. Stevens; R. Stock; M. Strikhanov; B. Stringfellow; M. Sumbera; X. Sun; X. M. Sun; Y. Sun; Z. Sun; B. Surrow; D. N. Svirida; T. J. M. Symons; M. A. Szelezniak; J. Takahashi; A. H. Tang; Z. Tang; T. Tarnowsky; J. H. Thomas; A. R. Timmins; D. Tlusty; M. Tokarev; S. Trentalange; R. E. Tribble; P. Tribedy; B. A. Trzeciak; O. D. Tsai; J. Turnau; T. Ullrich; D. G. Underwood; G. Van Buren; G. van Nieuwenhuizen; M. Vandenbroucke; J. A. Vanfossen, Jr.; R. Varma; G. M. S. Vasconcelos; A. N. Vasiliev; R. Vertesi; F. Videbæk; Y. P. Viyogi; S. Vokal; A. Vossen; M. Wada; F. Wang; G. Wang; H. Wang; J. S. Wang; X. L. Wang; Y. Wang; Y. Wang; G. Webb; J. C. Webb; G. D. Westfall; H. Wieman; S. W. Wissink; R. Witt; Y. F. Wu; Z. Xiao; W. Xie; K. Xin; H. Xu; J. Xu; N. Xu; Q. H. Xu; Y. Xu; Z. Xu; W. Yan; C. Yang; Y. Yang; Y. Yang; Z. Ye; P. Yepes; L. Yi; K. Yip; I-K. Yoo; N. Yu; Y. Zawisza; H. Zbroszczyk; W. Zha; J. B. Zhang; J. L. Zhang; S. Zhang; X. P. Zhang; Y. Zhang; Z. P. Zhang; F. Zhao; J. Zhao; C. Zhong; X. Zhu; Y. H. Zhu; Y. Zoulkarneeva; M. Zyzak

2014-04-05

252

Magnetic hydroxyapatite nanoparticles: An efficient adsorbent for the separation and removal of nitrate and nitrite ions from environmental samples.  

PubMed

A novel type of magnetic nanosorbent, hydroxyapatite-coated Fe2 O3 nanoparticles was synthesized and used for the adsorption and removal of nitrite and nitrate ions from environmental samples. The properties of synthesized magnetic nanoparticles were characterized by scanning electron microscopy, Fourier transform infrared spectroscopy, and X-ray powder diffraction. After the adsorption process, the separation of ?-Fe2 O3 @hydroxyapatite nanoparticles from the aqueous solution was simply achieved by applying an external magnetic field. The effects of different variables on the adsorption efficiency were studied simultaneously using an experimental design. The variables of interest were amount of magnetic hydroxyapatite nanoparticles, sample volume, pH, stirring rate, adsorption time, and temperature. The experimental parameters were optimized using a Box-Behnken design and response surface methodology after a Plackett-Burman screening design. Under the optimum conditions, the adsorption efficiencies of magnetic hydroxyapatite nanoparticles adsorbents toward NO3 (-) and NO2 (-) ions (100 mg/L) were in the range of 93-101%. The results revealed that the magnetic hydroxyapatite nanoparticles adsorbent could be used as a simple, efficient, and cost-effective material for the removal of nitrate and nitrite ions from environmental water and soil samples. PMID:25376506

Ghasemi, Ensieh; Sillanpää, Mika

2015-01-01

253

Pathogen detection in complex samples by quartz crystal microbalance sensor coupled to aptamer functionalized core-shell type magnetic separation.  

PubMed

A quartz crystal microbalance sensor (QCM) was developed for sensitive and specific detection of Salmonella enterica serovar typhimurium cells in food samples by integrating a magnetic bead purification system. Although many sensor formats based on bioaffinity agents have been developed for sensitive and specific detection of bacterial cells, the development of robust sensor applications for food samples remained a challenging issue. A viable strategy would be to integrate QCM to a pre-purification system. Here, we report a novel and sensitive high throughput strategy which combines an aptamer-based magnetic separation system for rapid enrichment of target pathogens and a QCM analysis for specific and real-time monitoring. As a proof-of-concept study, the integration of Salmonella binding aptamer immobilized magnetic beads to the aptamer-based QCM system was reported in order to develop a method for selective detection of Salmonella. Since our magnetic separation system can efficiently capture cells in a relatively short processing time (less than 10min), feeding captured bacteria to a QCM flow cell system showed specific detection of Salmonella cells at 100CFUmL(-1) from model food sample (i.e., milk). Subsequent treatment of the QCM crystal surface with NaOH solution regenerated the aptamer-sensor allowing each crystal to be used several times. PMID:25467500

Ozalp, Veli C; Bayramoglu, Gulay; Erdem, Zehra; Arica, M Yakup

2015-01-01

254

Phase separation and sharp magnetization steps in polycrystalline Pr 1- xCa xMnO 3  

NASA Astrophysics Data System (ADS)

Similar to the A-site and Mn-site substitution in orbital-charge ordered (OO-CO) polycrystalline Pr 0.5Ca 0.5MnO 3, the decrease in x from x=0.50 in Pr 1- xCa xMnO 3 can also induce sharp magnetization steps. It has been interpreted by a martensitic-like mechanism based on phase separation. With the decrease in x, the ideal Mn 3+/Mn 4+=1:1 orbital-charge ordering will be weakened, which is due to the disorder created by the extra Mn 3+ cations. Therefore, small ferromagnetic (FM) regions with higher symmetrical structure can be induced in the antiferromagnetic (AFM) OO-CO matrix with a strongly distorted structure. Due to their different symmetry, the strains will be created at the interface between the FM regions and the AFM matrix. In a magnetic field, the FM domains cannot grow continuously because of the existence of the interfacial strains. In order to achieve their further growth, a higher magnetic field must be applied to overcome the interfacial strains. As a result, sharp magnetization steps will appear in magnetization versus magnetic field curves of Pr 1- xCa xMnO 3. The x is smaller, the stability of the OO-CO phase is weaker, and then the interfacial strains become lower. Consequently, the critical magnetic field corresponding to the step appearance will decrease. Furthermore, the existence of the additional OO-CO state, which was recently reported by Asaka et al. [T. Asaka, S. Yamada, S. Tsutsumi, C. Tsuruta, K. Kimoto, T. Arima, T. Matsui, Phys. Rev. Lett. 88 (2002) 97201], has not been supported by our magnetic results and microscopic studies.

Zhu, Deliang; Cao, Peijiang; Maignan, A.; Raveau, B.

2007-10-01

255

Multifunctional superparamagnetic nanoshells: combining two-photon luminescence imaging, surface-enhanced Raman scattering and magnetic separation.  

PubMed

With the increasing need for multi-purpose analysis in the biomedical field, traditional single diagnosis methods cannot meet the requirements. Therefore new multifunctional technologies and materials for the integration of sample collection, sensing and imaging are in great demand. Core-shell nanoparticles offer a unique platform to combine multifunctions in a single particle. In this work, we have constructed a novel type of core-shell superparamagnetic nanoshell (Fe?O?@SiO?@Au), composed of a Fe?O? cluster core, a thin Au shell and a SiO? layer in between. The obtained multifunctional nanoparticles combine the magnetic properties and plasmonic optical properties effectively, which were well investigated by a number of experimental characterization methods and theoretical simulations. We have demonstrated that Fe?O?@SiO?@Au nanoparticles can be utilized for two-photon luminescence (TPL) imaging, near-infrared surface-enhanced Raman scattering (NIR SERS) and cell collection by magnetic separation. The TPL intensity could be further greatly enhanced through the plasmon coupling effect in the self-assembled nanoparticle chains, which were triggered by an external magnetic field. In addition, Fe?O?@SiO?@Au nanoparticles may have great potential applications such as enhanced magnetic resonance imaging (MRI) and photo-thermotherapy. Successful combination of multifunctions including magnetic response, biosensing and bioimaging in single nanoparticles allows further manipulation, real-time tracking, and intracellular molecule analysis of live cells at a single-cell level. PMID:25329447

Jin, Xiulong; Li, Haiyan; Wang, Shanshan; Kong, Ni; Xu, Hong; Fu, Qihua; Gu, Hongchen; Ye, Jian

2014-11-01

256

The UCLA/SLAC Ultra-High Gradient Cerenkov Wakefield Accelerator Experiment  

SciTech Connect

An experiment is planned to study the performance of dielectric Cerenkov wakefield accelerating structures at extremely high gradients in the GV/m range. This new UCLA/SLAC/USC collaboration will take advantage of the unique SLAC FFTB electron beam and its demonstrated ultra-short pulse lengths and high currents (e.g., {delta}{sub z} = 20 {micro}m at Q = 3 nC). The electron beam will be focused down and sent through varying lengths of fused silica capillary tubing with two different sizes: ID = 200 {micro}m/OD = 325 {micro}m and ID = 100 {micro}m/OD = 325 {micro}m. The pulse length of the electron beam will be varied in order to alter the accelerating gradient and probe the breakdown threshold of the dielectric structures. In addition to breakdown studies, we plan to collect and measure coherent Cerenkov radiation emitted from the capillary tube to gain information about the strength of the accelerating fields.

Thompson, M.C.; Badakov, H.; Rosenzweig, J.B.; Travish, G.; /UCLA; Hogan, M.; Ischebec, R.; Siemann, R.; Walz, D.; /SLAC; Scott, A.; /UC, Santa Barbara; Yoder, R.; /Manhattan Coll., Riverdale

2006-01-25

257

Preliminary Results from the UCLA/SLAC Ultra-High Gradient CerenkovWakefield Accelerator Experiment  

SciTech Connect

The first phase of an experiment to study the performance of dielectric Cerenkov wakefield accelerating structures at extremely high gradients in the GV/m range has been completed. This experiment takes advantage of the unique SLAC FFTB electron beam and its demonstrated ultra-short pulse lengths and high currents (e.g., {sigma}{sub z} = 20 {micro}m at Q = 3 nC). The FFTB electron beam has been successfully focused down and sent through varying lengths of fused silica capillary tubing with two different sizes: ID = 200 {micro}m/OD = 325 {micro}m and ID = 100 {micro}m/OD = 325 {micro}m. The pulse length of the electron beam was varied in the range 20 {micro}m < {sigma}{sub z} < 100 {micro}m which produced a range of electric fields between 2 and 20 GV/m at the inner surface of the dielectric tubes. We observed a sharp increase in optical emissions from the capillaries in the middle part of this surface field range which we believe indicates the transition between sustainable field levels and breakdown. If this initial interpretation is correct, the surfaced fields that were sustained equate to on axis accelerating field of several GV/m. In future experiments we plan to collect and measure coherent Cerenkov radiation emitted from the capillary tube to gain more information about the strength of the accelerating fields.

Thompson, M.C.; Badakov, H.; Rosenzweig, J.B.; Travish, G.; /UCLA; Hogan, M.; Ischebeck, R.; Kirby, N.; Siemann, R.; Walz, D.; /SLAC; Muggli, P.; /Southern California U.; Scott, A.; /UC, Santa Barbara; Yoder, R.; /Manhattan Coll., Riverdale

2008-02-06

258

Summary report of Working Group 3: Laser and high-gradient structure-based acceleration  

NASA Astrophysics Data System (ADS)

Working Group (WG) 3 assessed current challenges in developing advanced accelerators based on RF and laser-driven electromagnetic (EM) structures and surveyed the state-of-the-art research and methods addressing these challenges. A critical challenge for EM structures is the gradient limitation imposed by RF breakdown, pulsed heating, dark current, quench, thermal breakdown and other factors, depending on structure type, pulse width, duty cycle and regime of operation. Other challenges include developing approaches to reduce cost and size while at the same time greatly increasing performance. WG 3 examined a variety of approaches to the improve gradient, cost, size, and performance of advanced accelerators including dielectric loaded structures, photonic bandgap structures, solid-state crystal structures, terahertz generation technologies, inverse FELs and undulators, micro-accelerators and light sources, high gradient structures, and RF sources. These approaches cover a large range of frequencies and span a considerable parameter space including room temperature and superconducting devices, THz and optical EM, and dielectric-based structures. The state of the art was surveyed in RF source and component development, materials development, advanced micro-and nano-fabrication technologies, and surface coatings for accelerator applications. WG 3 also attempted to address challenges beyond gradient limitation, including simulation challenges, high order mode characterization, measurement, and damping, field distributions producing low emittance, power efficiency, and impact of fabrication tolerances.

Fazio, Michael V.; Anderson, Scott G.

2012-12-01

259

Demonstration of a 17-GHz, High-Gradient Accelerator with a Photonic-Band-Gap Structure  

NASA Astrophysics Data System (ADS)

We report the testing of a high gradient electron accelerator with a photonic-band-gap (PBG) structure. The photonic-band-gap structure confines a fundamental TM01-like accelerating mode, but does not support higher-order modes (HOM). The absence of HOM is a major advantage of the PBG accelerator, since it suppresses dangerous beam instabilities caused by wakefields. The PBG structure was designed as a triangular lattice of metal rods with a missing central rod forming a defect confining the TM01-like mode and allowing the electron beam to propagate along the axis. The design frequency of the six-cell structure was 17.14 GHz. The PBG structure was excited by 2 MW, 100 ns pulses. A 16.5 MeV electron beam was transmitted through the PBG accelerator. The observed electron beam energy gain of 1.4 MeV corresponds to an accelerating gradient of 35 MV/m, in excellent agreement with theory.

Smirnova, Evgenya I.; Kesar, Amit S.; Mastovsky, Ivan; Shapiro, Michael A.; Temkin, Richard J.

2005-08-01

260

Capture and separation of biomolecules using magnetic beads in a simple microfluidic channel without an external flow device.  

PubMed

The use of microfluidic devices and magnetic beads for applications in biotechnology has been extensively explored over the past decade. Many elaborate microfluidic chips have been used in efficient systems for biological assays. However most fail to achieve the ideal point of care (POC) status, as they require larger conventional external devices in conjunction with the microchip. This paper presents a simple technique to capture and separate biomolecules using magnetic bead movement on a microchip without the use of an external flow device. This microchip consisted of two well reservoirs (W1 and W2) connected via a tapered microchannel. Beads were dragged through the microchannel between the two wells at an equivalent speed to a permanent magnet that moved alongside the microchip. More than 95% of beads were transferred from W1 to W2 within 2 min at an average velocity of 0.7 mm s(-1). Enzymatic reactions were employed to test our microchip. Specifically, three assays were performed using the streptavidin coated magnetic beads as a solid support to capture and transfer biomolecules: (1) non-specific adsorption of the substrate, 6-8-difluoro-4-methylumbelliferyl phosphate (DiFMUP), (2) capture of the enzyme, biotinylated alkaline phosphatase (AP), and (3) separation of AP from DiFMUP. Our non-specific adsorption assay indicated that the microchip was capable of transferring the beads with less than 0.002% carryover of DiFMUP. Our capture assay indicated efficient capture and transfer of AP with beads to W2 containing DiFMUP, where the transferred AP converted 100% of DiFMUP to DiFMU within 15 minutes. Our separation assay showed effective separation of AP from DiFMUP and elucidated the binding capacity of the beads for AP. The leftover unbound AP in W1 converted 100% of DiFMUP within 10 minutes and samples with less than the full bead capacity of AP (i.e. all AP was transferred) did not convert any of the DiFMUP. The immobilization of AP on the bead surface resulted in 32% reduced enzymatic speed compared to that of free AP in solution, as a result of altered protein conformation and/or steric hindrance of the catalytic site. Overall, this microfluidic platform was established as a simple, efficient and effective approach for separating biomolecules without any flow apparatus. PMID:24051541

Wang, Jingjing; Morabito, Kenneth; Erkers, Tom; Tripathi, Anubhav

2013-11-01

261

Methyl parathion imprinted polymer nanoshell coated on the magnetic nanocore for selective recognition and fast adsorption and separation in soils.  

PubMed

Core-shell magnetic methyl parathion (MP) imprinted polymers (Fe3O4@MPIPs) were fabricated by a layer-by-layer self-assembly process. In order to take full advantage of the synergistic effect of hydrogen-binding interactions and ?-? accumulation between host and guest for molecular recognition, methacrylic acid and 4-vinyl pyridine were chosen as co-functional monomers and their optimal proportion were investigated. The core-shell and crystalline structure, morphology and magnetic properties of Fe3O4@MPIPs were characterized. The MP-imprinted nanoshell was almost uniform and about 100nm thick. Binding experiments demonstrated that Fe3O4@MPIPs possessed excellent binding properties, including high adsorption capacity and specific recognition, as well as fast adsorption kinetics and a fast phase separation rate. The equilibration adsorption capacity reached up to 9.1mg/g, which was 12 times higher than that of magnetic non-imprinted polymers, while adsorption reached equilibrium within 5min at a concentration of 0.2mmol/L. Furthermore, Fe3O4@MPIPs successfully provided selective separation and removal of MP in soils with a recovery and detection limit of 81.1-87.0% and 5.2ng/g, respectively. PMID:24275470

Xu, Shiying; Guo, Changjuan; Li, Yongxian; Yu, Zerong; Wei, Chaohai; Tang, Youwen

2014-01-15

262

Easy-separable magnetic nanoparticle-supported Pd catalysts: Kinetics, stability and catalyst re-use  

Microsoft Academic Search

A series of novel palladium-based catalysts supported on magnetic nanoparticles with diameters of 7–17nm have been prepared and evaluated in C–C coupling, hydrogenation and amination reactions. One type of catalyst used palladium complexes containing phosphine and\\/or acetate ligands for applications in Suzuki and Heck reactions. The second type consisted of Pd(0)-functionalised magnetic cores for use in hydrogenation and C–C coupling.

Urszula Laska; Christopher G. Frost; Gareth J. Price; Pawel K. Plucinski

2009-01-01

263

Eddy current and total power loss separation in the iron–phosphate–polyepoxy soft magnetic composites  

Microsoft Academic Search

This work investigates the magnetic properties of iron–phosphate–polyepoxy soft magnetic composite materials. FTIR spectra, EDX analysis, distribution maps, X-ray diffraction pattern and density measurements show that the particles surface layer contains a thin layer of nanocrystalline\\/amorphous phosphate with high coverage of powders surface. In this paper, a formula for calculating the eddy current loss and total loss components by loss

A. H. Taghvaei; H. Shokrollahi; K. Janghorban; H. Abiri

2009-01-01

264

New high performance hybrid magnet plates for DNA separation andbio-technology applications  

SciTech Connect

A new class of magnet plates for biological and industrial applications has recently been developed at the D.O.E. Joint Genome Institute and Lawrence Berkeley National Laboratory (JGI/LBNL). These devices utilize hybrid technology that combines linear permanent magnet material and ferromagnetic material to produce significantly higher fields and gradients than currently available commercial magnet plates. These hybrid structures incorporate ferromagnetic poles that can be easily shaped to produce complex field distributions for specialized applications. The higher maximum fields and strong gradients of the hybrid structures result in greater holding forces on magnetized targets that are being processed as well as faster draw-down. Current development versions of these magnet plates have exhibited maximum fields in excess of 9000.0 Gauss. The design of these structures is easily scalable to allow for field increases to significantly above 1.0 tesla (10000.0gauss). Author's note: 11000.0 Gauss peak fields have been achieved as of January 2005.

Humphries, David; Pollard, Martin; Elkin, Chris; Petermann, Karl; Reiter, Charles; Cepeda, Mario

2004-08-02

265

Superconductivity, metastability and magnetic field induced phase separation in the atomic limit of the Penson-Kolb-Hubbard model  

E-print Network

We present the analysis of paramagnetic effects of magnetic field ($B$) (Zeeman term) in the zero-bandwidth limit of the extended Hubbard model for arbitrary chemical potential $\\mu$ and electron density $n$. The effective Hamiltonian considered consists of the on-site interaction $U$ and the intersite charge exchange term $I$, determining the hopping of electron pairs between nearest-neighbour sites. The model has been analyzed within the variational approach, which treats the on-site interaction term exactly and the intersite interactions within the mean-field approximation (rigorous in the limit of infinite dimensions $d\\rightarrow+\\infty$). In this report we focus on metastable phases as well as phase separated (PS) states involving superconducting (SS) and nonordered (NO) phases and determine their ranges of occurrence for $U/I_0=1.05$ ($I_0=zI$) in the presence of magnetic field $B\

Kapcia, Konrad Jerzy

2014-01-01

266

Dependence of magnetic field sensitivity of a magnetoelectric laminate sensor pair on separation distance: Effect of mutual inductance  

NASA Astrophysics Data System (ADS)

The effect of mutual inductance on the performance of a pair of Metglas/Pb(Zr,Ti)O3 laminate magnetoelectric (ME) sensors has been studied. The effective value of the ME coefficient (?ME) for the laminates was reduced when the distance between was < 40 mm. Separating the two laminates by distances of > 40 mm, the effect of mutual inductance was small. The laminates exhibited the maximum values of ?ME. The ME sensor unit with two laminates connected in parallel had higher magnetic field sensitivities.

Li, Menghui; Wang, Yaojin; Gao, Junqi; Gray, David; Li, Jiefang; Viehland, D.

2012-02-01

267

Macroinvertebrate community responses to gravel augmentation in a high-gradient, Southeastern regulated river  

SciTech Connect

Sediment transport, one of the key processes of river systems, is altered or stopped by dams, leaving lower river reaches barren of sand and gravel, both of which are essential habitat for fish and macroinvertebrates. One way to compensate for losses in sediment is to supplement gravel to river reaches below impoundments. Because gravel addition has become a widespread practice, it is essential to evaluate the biotic response to restoration projects in order to improve the efficacy of future applications. The purpose of our study was to evaluate the response of the macroinvertebrate community to gravel addition in a high-gradient, regulated river in western North Carolina. We collected benthic macroinvertebrate samples from gravel-enhanced areas and unenhanced areas for 1 season before gravel addition, and for 4 seasons afterwards. Repeated measures multivariate analysis of variance indicated that the responses of macroinvertebrates to gravel addition were generally specific to individual taxa or particular functional feeding groups and did not lead to consistent patterns in overall family richness, diversity, density, or evenness. Non-metric multi-dimensional scaling showed that shifts in macroinvertebrate community composition were temporary and dependent upon site conditions and season. Correlations between macroinvertebrate response variables and substrate microhabitat variables existed with or without the inclusion of data from enhanced areas, which suggests that substrate-biotic relationships were present before gravel addition. A review of the current literature suggests that the responses of benthic macroinvertebrates to substrate restoration are inconsistent and dependent upon site conditions and the degree habitat improvement of pre-restoration site conditions.

McManamay, Ryan A [ORNL; Orth, Dr. Donald J [Virginia Polytechnic Institute and State University; Dolloff, Dr. Charles A [United States Department of Agriculture (USDA), United States Forest Service (USFS) and Virginia Pol

2013-01-01

268

Microcystin-LR removal from aqueous solutions using a magnetically separable N-doped TiO2 nanocomposite under visible light irradiation  

EPA Science Inventory

The performance of magnetically separable N-doped TiO2 was found to be significantly improved when compared with a non-magnetic N-doped TiO2 for the aqueous removal of cyanotoxin Microcystin-LR. The observed enhanced photocatalytic activity may be related to the presence of ferri...

269

Cocaine detection via rolling circle amplification of short DNA strand separated by magnetic beads  

Microsoft Academic Search

A novel and sensitive fluorescence biosensor based on aptamer and rolling circle amplification for the determination of cocaine was developed in the present work. Here cocaine aptamers immobilized onto Au nanoparticles modified magnetic beads hybridized with short DNA strand. In the presence of cocaine, the short DNA strand was displaced from aptamer owing to cocaine specially binding with aptamer. Next,

Cuiping Ma; Wenshuo Wang; Qing Yang; Chao Shi; Lijie Cao

2011-01-01

270

Studies in matter antimatter separation and in the origin of lunar magnetism  

NASA Technical Reports Server (NTRS)

A progress report, covering lunar and planetary research is introduced. Data cover lunar ionospheric models, lunar and planetary geology, and lunar magnetism. Wind tunnel simulations of Mars aeolian problems and a comparative study of basaltic analogs of Lunar and Martial volcanic features was discussed.

Barker, W. A.; Greeley, R.; Parkin, C.; Aggarwal, H.; Schultz, P.

1975-01-01

271

Magnetic and highly recyclable macroporous carbon nanotubes for spilled oil sorption and separation.  

PubMed

Development of sorbent materials with high selectivity and sorption capacity, easy collection and recyclability is demanding for spilled oil recovery. Although many sorption materials have been proposed, a systematic study on how they can be reused and possible performance degradation during regeneration remains absent. Here we report magnetic carbon nanotube sponges (Me-CNT sponge), which are porous structures consisting of interconnected CNTs with rich Fe encapsulation. The Me-CNT sponges show high mass sorption capacity for diesel oil reached 56 g/g, corresponding to a volume sorption capacity of 99%. The sponges are mechanically strong and oil can be squeezed out by compression. They can be recycled using through reclamation by magnetic force and desorption by simple heat treatment. The Me-CNT sponges maintain original structure, high capacity, and selectivity after 1000 sorption and reclamation cycles. Our results suggest that practical application of CNT macrostructures in the field of spilled oil recovery is feasible. PMID:23721652

Gui, Xuchun; Zeng, Zhiping; Lin, Zhiqiang; Gan, Qiming; Xiang, Rong; Zhu, Yuan; Cao, Anyuan; Tang, Zikang

2013-06-26

272

Mass separation of a multicomponent plasma flow in a curvilinear magnetic field  

SciTech Connect

The motion of a metal plasma flow of a vacuum-arc discharge in a transportation plasma-optical system with a curvilinear magnetic field is studied experimentally and numerically. The flow position at the output of the system is shown to depend on the cathode material, which determines the mass-to-charge ratio of plasma ions. As a result, the flow with a greater ion mass-to-charge ratio moves along a trajectory with a larger radius. A similar effect is observed in the case of a multicomponent plasma flow generated by a composite cathode. The results of two-fluid MHD simulations of a plasma flow propagating in a curvilinear magnetic field agree qualitatively with the experimental data.

Papernyi, V. L.; Krasov, V. I. [Irkutsk State University (Russian Federation)

2011-11-15

273

PDMAEMA-grafted core-shell-corona particles for nonviral gene delivery and magnetic cell separation.  

PubMed

Monodisperse, magnetic nanoparticles as vectors for gene delivery were successfully synthesized via the grafting-from approach. First, oleic acid stabilized maghemite nanoparticles (?-Fe2O3) were encapsulated with silica utilizing a reverse microemulsion process with simultaneous functionalization with initiating sites for atom transfer radical polymerization (ATRP). Polymerization of 2-(dimethylamino)ethyl methacrylate (DMAEMA) from the core-shell nanoparticles led to core-shell-corona hybrid nanoparticles (?-Fe2O3@silica@PDMAEMA) with an average grafting density of 91 polymer chains of DP(n) = 540 (PDMAEMA540) per particle. The permanent attachment of the arms was verified by field-flow fractionation. The dual-responsive behavior (pH and temperature) was confirmed by dynamic light scattering (DLS) and turbidity measurements. The interaction of the hybrid nanoparticles with plasmid DNA at various N/P ratios (polymer nitrogen/DNA phosphorus) was investigated by DLS and zeta-potential measurements, indicating that for N/P ? 7.5 the complexes bear a positive net charge and do not undergo secondary aggregation. The hybrids were tested as transfection agents under standard conditions in CHO-K1 and L929 cells, revealing transfection efficiencies >50% and low cytotoxicity at N/P ratios of 10 and 15, respectively. Due to the magnetic properties of the hybrid gene vector, it is possible to collect most of the cells that have incorporated a sufficient amount of magnetic material by using a magnetic activated cell sorting system (MACS). Afterward, cells were further cultivated and displayed a transfection efficiency of ca. 60% together with a high viability. PMID:23889326

Majewski, Alexander P; Stahlschmidt, Ullrich; Jérôme, Valérie; Freitag, Ruth; Müller, Axel H E; Schmalz, Holger

2013-09-01

274

CALCULATING SEPARATE MAGNETIC FREE ENERGY ESTIMATES FOR ACTIVE REGIONS PRODUCING MULTIPLE FLARES: NOAA AR11158  

SciTech Connect

It is well known that photospheric flux emergence is an important process for stressing coronal fields and storing magnetic free energy, which may then be released during a flare. The Helioseismic and Magnetic Imager (HMI) on board the Solar Dynamics Observatory (SDO) captured the entire emergence of NOAA AR 11158. This region emerged as two distinct bipoles, possibly connected underneath the photosphere, yet characterized by different photospheric field evolutions and fluxes. The combined active region complex produced 15 GOES C-class, two M-class, and the X2.2 Valentine's Day Flare during the four days after initial emergence on 2011 February 12. The M and X class flares are of particular interest because they are nonhomologous, involving different subregions of the active region. We use a Magnetic Charge Topology together with the Minimum Current Corona model of the coronal field to model field evolution of the complex. Combining this with observations of flare ribbons in the 1600 A channel of the Atmospheric Imaging Assembly on board SDO, we propose a minimization algorithm for estimating the amount of reconnected flux and resulting drop in magnetic free energy during a flare. For the M6.6, M2.2, and X2.2 flares, we find a flux exchange of 4.2 Multiplication-Sign 10{sup 20} Mx, 2.0 Multiplication-Sign 10{sup 20} Mx, and 21.0 Multiplication-Sign 10{sup 20} Mx, respectively, resulting in free energy drops of 3.89 Multiplication-Sign 10{sup 30} erg, 2.62 Multiplication-Sign 10{sup 30} erg, and 1.68 Multiplication-Sign 10{sup 32} erg.

Tarr, Lucas; Longcope, Dana; Millhouse, Margaret [Department of Physics, Montana State University, Bozeman, MT 59717 (United States)

2013-06-10

275

Calculating Separate Magnetic Free Energy Estimates for Active Regions Producing Multiple Flares: NOAA AR11158  

E-print Network

It is well known that photospheric flux emergence is an important process for stressing coronal fields and storing magnetic free energy, which may then be released during a flare. The \\emph{Helioseismic and Magnetic Imager} (HMI) onboard the \\emph{Solar Dynamics Observatory} (SDO) captured the entire emergence of NOAA AR 11158. This region emerged as two distinct bipoles, possibly connected underneath the photosphere, yet characterized by different photospheric field evolutions and fluxes. The combined active region complex produced 15 GOES C--class, 2 M--class, and the X2.2 Valentine's Day Flare during the four days after initial emergence on February 12th, 2011. The M and X class flares are of particular interest because they are nonhomologous, involving different subregions of the active region. We use a Magnetic Charge Topology together with the Minimum Current Corona model of the coronal field to model field evolution of the complex. Combining this with observations of flare ribbons in the 1600\\AA\\ chann...

Tarr, Lucas A; Millhouse, Margaret

2013-01-01

276

Design of Countercurrent Separation of Ginkgo biloba Terpene Lactones by Nuclear Magnetic Resonance  

PubMed Central

Terpene lactones such as bilobalide, ginkgolides A, B, C, and J are major bioactive compounds of Ginkgo biloba L. Purification of these compounds is tedious due to their similar chemical properties. For the purpose of developing an effective and efficient method for both analytical and preparative separation of terpene lactones in G. biloba, an innovative orthogonality-enhanced high-speed countercurrent chromatography (HSCCC) method was established. Taking advantage of quantitative 1H NMR (qHNMR) methodology, partition coefficients (K) of individual terpene lactones were calculated directly from crude G. biloba leaf extract, using their H-12 signals as distinguishing feature. The partitioning experiment assisted the design of a two dimensional (2D) HSCCC procedure using a pair of orthogonal HSCCC solvent systems (SSs), ChMWat +4 and HEMSoWat +3/0.05%. It was surprising that the resolution of ginkgolides A and B was improved by 25% in the HEMWat +3 SS modified with 0.5% DMSO. Consequently, all five terpene lactones could be well separated with qHNMR purity > 95% from G. biloba leaf extract. The separation was further evaluated by offline qHNMR analysis of HSCCC fractions associated with Gaussian curve fitting. The results showed less than 2% error in HSCCC retention predicted from the partitioning experiment. This compelling consistency demonstrates that qHNMR-derived K determination (“K-by-NMR”) can be used to predict CCC fractionation and target purification of analytes from complex mixtures. Furthermore, Gaussian curve fitting enabled an accurate prediction of less than 2% impurity in the CCC fraction, which demonstrates its potential as a powerful tool to study the presence of minor constituents, especially when they are beyond the detection limit of conventional spectroscopic detectors. PMID:22579361

Qiu, Feng; Friesen, Brent J.; McAlpine, James B.; Pauli, Guido F.

2012-01-01

277

Enantioselective separation of chiral aromatic amino acids with surface functionalized magnetic nanoparticles.  

PubMed

Chiral resolution aromatic amino acids, DL-tryptophan (DL-Trp), DL-phenylalanine (DL-Phe), DL-tyrosine (DL-Tyr) from phosphate buffer solution was achieved in present study employing the concept of selective adsorption by surface functionalized magnetic nanoparticles (MNPs). Surfaces of magnetic nanoparticles were functionalized with silica and carboxymethyl-?-cyclodextrin (CMCD) to investigate their adsorption resolution characteristics. Resolution of enantiomers from racemic mixture was quantified in terms of enantiomeric excess using chromatographic method. The MNPs selectively adsorbed L-enantiomers of DL-Trp, DL-Phe, and DL-Tyr from racemic mixture and enantiomeric excesses (e.e.) were determined as 94%, 73% and 58%, respectively. FTIR studies demonstrated that hydrophobic portion of enantiomer penetrated into hydrophobic cavity of cyclodextrin molecules to form inclusion complex. Furthermore, adsorption site was explored using XPS and it was revealed that amino group at chiral center of the amino acid molecule formed hydrogen bond with secondary hydroxyl group of CMCD molecule and favorability of hydrogen bond formation resulted in selective adsorption of L-enantiomer. Finally, stability constant (K) and Gibbs free energy change (-?G°) for inclusion complexation of CMCD with L-/D-enantiomers of amino acids were determined using spectroflurometry in aqueous buffer solution. Higher binding constants were obtained for inclusion complexation of CMCD with L-enantiomers compared to D-enantiomers which stimulated enantioselective properties of CMCD functionalized magnetite silica nanoparticles. PMID:23384689

Ghosh, Sudipa; Fang, Tan Hui; Uddin, M S; Hidajat, K

2013-05-01

278

Improvement of the separation of tumour cells from peripheral blood cells using magnetic nanoparticles  

NASA Astrophysics Data System (ADS)

Circulating tumour cells are a key challenge in tumour therapy. Numerous approaches are on the way to achieving the elimination of these potential sources of metastasis formation. Antibody-directed magnetic cell sorting is supposed to enrich tumour cells with high selectivity, but low efficiency. The short term application of carboxymethyl dextran (CMD) coated magnetit/maghemit nanoparticles allows the discrimination of tumour cells from leukocytes. In the present work we show that the interaction of CMD nanoparticles is cell-type specific and time dependent. The breast cancer cell line MCF-7 and the CML cell line K-562 are characterized by a rapid and high interaction rate, whereas leukocytes exhibit a decelerated behaviour. The addition of carboxymethyl dextran or glucose stimulated the magnetic labelling of leukocytes. The variation of the degree of substitution of dextran with carboxymethyl groups did not affect the labelling profile of leukocytes and MCF-7 cells. In order to verify the in vitro results, whole blood samples from 13 cancer patients were analysed ex vivo. Incubation of the purified leukocyte fraction with CMD nanoparticles in the presence of low amounts of plasma reduced the overall cell content in the positive fraction. In contrast, the absolute number of residual tumour cells in the positive fraction was 90% of the initial amount.

Schwalbe, M.; Pachmann, K.; Höffken, K.; Clement, J. H.

2006-09-01

279

Transmitted light relaxation and microstructure evolution of ferrofluids under gradient magnetic fields  

NASA Astrophysics Data System (ADS)

Using light transmission experiments and optical microscope observations with a longitudinal gradient magnetic field configuration, the relationship between the behavior of the transmitted light relaxation and the microstructure evolution of ionic ferrofluids in the central region of an axisymmetric field is investigated. Under a low-gradient magnetic field, there are two types of relaxation process. When a field is applied, the transmitted light intensity decreases to a minimum within a time on the order of 101-102 s. It is then gradually restored, approaching its initial value within a time on the order of 102 s. This is type I relaxation, which corresponds to the formation of magnetic columns. After the transmission reaches this value, it either increases or decreases slowly, stabilizing within a time on the order of 103 s, according to the direction of the field gradient. This is a type II relaxation, which results from the shadowing effect, corresponding to the motion of the magnetic columns under the application of a gradient force. Under a magnetic field with a centripetal high-gradient (magnetic materials subjected to a force pointing toward the center of the axisymmetric field), the transmitted light intensity decreases monotonously and more slowly than that under a low-gradient field. Magnetic transport and separation resulted from magnetophoresis under high-gradient fields, changing the formation dynamics of the local columns and influencing the final state of the column system.

Huang, Yan; Li, Decai; Li, Feng; Zhu, Quanshui; Xie, Yu

2015-03-01

280

Levitation Performance of Two Opposed Permanent Magnet Pole-Pair Separated Conical Bearingless Motors  

NASA Technical Reports Server (NTRS)

In standard motor applications, rotor suspension with traditional mechanical bearings represents the most economical solution. However, in certain high performance applications, rotor suspension without contacting bearings is either required or highly beneficial. Examples include applications requiring very high speed or extreme environment operation, or with limited access for maintenance. This paper expands upon a novel bearingless motor concept, in which two motors with opposing conical air-gaps are used to achieve full five-axis levitation and rotation of the rotor. Force in this motor is created by deliberately leaving the motor s pole-pairs unconnected, which allows the creation of different d-axis flux in each pole pair. This flux imbalance is used to create lateral force. This approach is different than previous bearingless motor designs, which require separate windings for levitation and rotation. This paper examines the predicted and achieved suspension performance of a fully levitated prototype bearingless system.

Kascak, Peter; Jansen, Ralph; Dever, Timothy; Nagorny, Aleksandr; Loparo, Kenneth

2013-01-01

281

Identification of new astatine isotopes using the gas-filled magnetic separator, SASSY  

SciTech Connect

A He-filled on-line mass separator system was built at the SuperHILAC and used to study the fusion products in the reaction /sup 56/Fe + /sup 141/Pr. The new neutron-deficient isotopes /sup 194/At and /sup 195/At were produced in this bombardment as three- and two- neutron-out products, respectively, and were identified by the ..cap alpha..-..cap alpha.. time-correlation technique. The measured ..cap alpha.. energies and half lives are 7.20 +- 0.02 MeV and 180 +- 80 msec for /sup 194/At, and 7.12 +- 0.02 MeV and 200 +- 100 msec for /sup 195/At. 66 references.

Yashita, S.

1984-02-01

282

Identification of new astatine isotopes using the gas-filled magnetic separator, Sassy  

SciTech Connect

A He-filled on-line separator system was built at the SuperHILAC and used to study the fusion products in the reaction /sup 56/Fe + /sup 141/Pr. The new neutron-deficient isotopes /sup 194/At and /sup 195/At were produced in this bombardment as three- and two-neutron-out products, respectively, and were identified by the ..cap alpha..-..cap alpha.. time-correlation technique. The measured ..cap alpha.. energies and half lives are 7.20 +/- 0.02 MeV and 180 +/- 80 msec for /sup 194/At, and 7.12 +/- 0.02 MeV and 200 +/- 100 msec for /sup 195/At.

Yashita, S.

1983-01-01

283

Local CP-violation and electric charge separation by magnetic fields from lattice QCD  

E-print Network

We study local CP-violation on the lattice by measuring the local correlation between the topological charge density and the electric dipole moment of quarks, induced by a constant external magnetic field. This correlator is found to increase linearly with the external field, with the coefficient of proportionality depending only weakly on temperature. Results are obtained on lattices with various spacings, and are extrapolated to the continuum limit after the renormalization of the observables is carried out. This renormalization utilizes the gradient flow for the quark and gluon fields. Our findings suggest that the strength of local CP-violation in QCD with physical quark masses is about an order of magnitude smaller than a model prediction based on nearly massless quarks in domains of constant gluon backgrounds with topological charge. We also show numerical evidence that the observed local CP-violation correlates with spatially extended electric dipole structures in the QCD vacuum.

G. S. Bali; F. Bruckmann; G. Endrodi; Z. Fodor; S. D. Katz; A. Schafer

2014-03-31

284

EVIDENCE FOR TWO SEPARATE BUT INTERLACED COMPONENTS OF THE CHROMOSPHERIC MAGNETIC FIELD  

SciTech Connect

Chromospheric fibrils are generally thought to trace out low-lying, mainly horizontal magnetic fields that fan out from flux concentrations in the photosphere. A high-resolution ({approx}0.''1 pixel{sup -1}) image, taken in the core of the Ca II 854.2 nm line and covering an unusually large area, shows the dark fibrils within an active region remnant as fine, looplike features that are aligned parallel to each other and have lengths comparable to a supergranular diameter. Comparison with simultaneous line-of-sight magnetograms confirms that the fibrils are centered above intranetwork areas (supergranular cell interiors), with one end rooted just inside the neighboring plage or strong unipolar network but the other endpoint less clearly defined. Focusing on a particular arcade-like structure lying entirely on one side of a filament channel (large-scale polarity inversion), we find that the total amount of positive-polarity flux underlying this 'fibril arcade' is {approx}50 times greater than the total amount of negative-polarity flux. Thus, if the fibrils represent closed loops, they must consist of very weak fields (in terms of total magnetic flux), which are interpenetrated by a more vertical field that contains most of the flux. This surprising result suggests that the fibrils in unipolar regions connect the network to the nearby intranetwork flux, while the bulk of the network flux links to remote regions of the opposite polarity, forming a second, higher canopy above the fibril canopy. The chromospheric field near the edge of the network thus has an interlaced structure resembling that in sunspot penumbrae.

Reardon, K. P. [Osservatorio Astrofisico di Arcetri, 50125 Firenze (Italy); Wang, Y.-M.; Warren, H. P. [Space Science Division, Naval Research Laboratory, Washington, DC 20375-5352 (United States); Muglach, K., E-mail: kreardon@arcetri.astro.it, E-mail: yi.wang@nrl.navy.mil, E-mail: hwarren@nrl.navy.mil, E-mail: karin.muglach@nasa.gov [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States)

2011-12-01

285

The effect of charge separation on nonlinear electrostatic waves in a magnetized dusty plasma with two-temperature ions  

SciTech Connect

In view of the observations of parallel (to Earth's magnetic field) spiky electric field structures by the FAST satellite, a theoretical study is conducted using a dusty plasma model comprising Boltzmann distributed hot and cool ions, Boltzmann electrons and a negatively charged cold dust fluid to investigate the existence of similar low frequency nonlinear electrostatic waves in a dusty plasma which could have a similar appearance as the observed waveforms. Charge separation effects are incorporated into our model by the inclusion of Poisson's equation as opposed to assuming quasineutrality. The system of nonlinear equations is then numerically solved. The resulting electric field structure is examined as a function of various plasma parameters such as Mach number, driving electric field amplitude, bulk dust drift speed, particle densities and particle temperatures.

Maharaj, S. K. [Hermanus Magnetic Observatory, P.O. Box 32, Hermanus 7200 (South Africa); Bharuthram, R. [University of the Western Cape, Modderdam Road, Bellville 7530 (South Africa); Pillay, S. R. [University of KwaZulu-Natal, Private Bag X54001, Durban 4000 (South Africa); Singh, S. V.; Reddy, R. V.; Lakhina, G. S. [Indian Institute of Geomagnetism, New Panvel, Navi Mumbai-410218 (India)

2008-09-07

286

Signature of magnetic phase separation in the ground state of Pr1-xCaxMnO3  

SciTech Connect

Neutron scattering has been used to investigate the evolution of the long- and short-range charge-ordered (CO), ferromagnetic (FM), and antiferromagnetic (AF) correlations in single crystals of $\\rm Pr_{1-x}Ca_{x}MnO_3$ ($x$ = 0.3, 0.35 and 0.4). These correlations are a ssociated with the existence of spin clusters with populations that drastically depend on the doping ($x$) and temperature. Concentrated spin clusters coexist with long-range canted AF order in a wide temperature range for $x$ = 0.3 while clusters do not appear in the $x$ = 0.4 crystal. In contrast, both CO and AF order parameters in the $x$ = 0.35 crystal show a precipitous decrease below $\\sim$ 35 K where spin clusters form. These results provide direct evidence of magnetic phase separation and indicate that there is a critical doping $x_{c}$ (close to $x$ = 0.35) that divides the phase-separated site-centered from the homogeneous bond-centered or charge-disproportionated CO ground state.

Sha, Hao [Florida International University, Miami; Ye, Feng [ORNL; Dai, Pengcheng [ORNL; Fernandez-Baca, Jaime A [ORNL; Mesa, Dalgis [ORNL; Lynn, J. W. [National Institute of Standards and Technology (NIST); Tomioka, Y. [Correlated Electron Research Center (CERC), Japan; Tokura, Y. [University of Tokyo, Tokyo, Japan; Zhang, Jiandi [Florida International University, Miami

2008-01-01

287

Separation and purification of Si from solidification of hypereutectic Al-Si melt under rotating magnetic field  

NASA Astrophysics Data System (ADS)

A low-cost and high-efficiency method to purify Si directly from cheap MG-Si at low temperature was proposed and demonstrated in this paper, which used power frequency rotating magnetic field (RMF) to separate the primary Si from a hypereutectic Al-Si alloy and was followed by the acid peeling. The separation mechanism was based on the flow characteristic of melt under RMF and the cooling condition of the liquid metal. A Si-rich layer with Si content of 65-59 wt% was formed in the periphery of alloy, while the inner microstructure of the alloy was mainly the Al-Si eutectic structure. The refined silicon was collected after aqua regia leaching, and had much fewer typical impurities (Fe, Ti, Ca, B, P) than those in MG-Si, and the metallic impurities besides Al had removal fraction higher than 98%, which is mainly ascribed to the segregation effect of Al-30Si alloy during solidification under RMF.

Jie, J. C.; Zou, Q. C.; Wang, H. W.; Sun, J. L.; Lu, Y. P.; Wang, T. M.; Li, T. J.

2014-08-01

288

Utility of Temporally-Extended Signal Space Separation Algorithm for Magnetic Noise from Vagal Nerve Stimulators  

PubMed Central

Object To evaluate the utility of a temporally-extended Signal Space Separation algorithm (tSSS) for patients with vagal nerve stimulator (VNS) Methods We evaluated median nerve somatosensory evoked responses (SER) of magnetoencephalography (MEG) in 27 VNS patients (48 sides) with/without tSSS processing. We classified SER dipoles as ‘acceptable’ if: A) the location of the dipole was in the expected location in the central sulcus, and B) the Goodness Of Fit value (GOF) was greater than 80%. We evaluated 1) the number of sides which produced acceptable dipoles in each dataset (i.e. with/without tSSS processing), and in cases where the both data produced reliable dipoles, 2) compared their GOFs and the 95% Confidence Volumes (CV) (mm3). Statistical differences in the GOF and CV between with/without tSSS conditions were determined by paired t test. Results Only 11 (23%) responses had reliable dipoles without tSSS processing, while all 48 (100%) had acceptable dipoles under tSSS processing. Additionally, the latter group had significantly higher GOF (increased by 7% on average) and lower CV (mean decrease of 200 mm3) than the former (p < 0.01). Conclusion Processing with tSSS quantitatively improves dipole fitting of known sources in VNS patients. Significance This algorithm permits satisfactory MEG testing in the relatively commonly encountered epilepsy patient with VNS. PMID:22727713

Kakisaka, Yosuke; Mosher, John C.; Wang, Zhong I.; Jin, Kazutaka; Dubarry, Anne-Sophie; Alexopoulos, Andreas V.; Burgess, Richard C.

2014-01-01

289

Recovery of iron from high phosphorus oolitic iron ore using coal-based reduction followed by magnetic separation  

NASA Astrophysics Data System (ADS)

Oolitic iron ore is one of the most important iron resources. This paper reports the recovery of iron from high phosphorus oolitic iron ore using coal-based reduction and magnetic separation. The influences of reduction temperature, reduction time, C/O mole ratio, and CaO content on the metallization degree and iron recovery were investigated in detail. Experimental results show that reduced products with the metallization degree of 95.82% could be produced under the optimal conditions (i.e., reduction temperature, 1250°C; reduction time, 50 min; C/O mole ratio, 2.0; and CaO content, 10wt%). The magnetic concentrate containing 89.63wt% Fe with the iron recovery of 96.21% was obtained. According to the mineralogical and morphologic analysis, the iron minerals had been reduced and iron was mainly enriched into the metallic iron phase embedded in the slag matrix in the form of spherical particles. Apatite was also reduced to phosphorus, which partially migrated into the metallic iron phase.

Sun, Yong-sheng; Han, Yue-xin; Gao, Peng; Wang, Ze-hong; Ren, Duo-zhen

2013-05-01

290

Erythrocyte Enrichment in Hematopoietic Progenitor Cell Cultures Based on Magnetic Susceptibility of the Hemoglobin  

PubMed Central

Using novel media formulations, it has been demonstrated that human placenta and umbilical cord blood-derived CD34+ cells can be expanded and differentiated into erythroid cells with high efficiency. However, obtaining mature and functional erythrocytes from the immature cell cultures with high purity and in an efficient manner remains a significant challenge. A distinguishing feature of a reticulocyte and maturing erythrocyte is the increasing concentration of hemoglobin and decreasing cell volume that results in increased cell magnetophoretic mobility (MM) when exposed to high magnetic fields and gradients, under anoxic conditions. Taking advantage of these initial observations, we studied a noninvasive (label-free) magnetic separation and analysis process to enrich and identify cultured functional erythrocytes. In addition to the magnetic cell separation and cell motion analysis in the magnetic field, the cell cultures were characterized for cell sedimentation rate, cell volume distributions using differential interference microscopy, immunophenotyping (glycophorin A), hemoglobin concentration and shear-induced deformability (elongation index, EI, by ektacytometry) to test for mature erythrocyte attributes. A commercial, packed column high-gradient magnetic separator (HGMS) was used for magnetic separation. The magnetically enriched fraction comprised 80% of the maturing cells (predominantly reticulocytes) that showed near 70% overlap of EI with the reference cord blood-derived RBC and over 50% overlap with the adult donor RBCs. The results demonstrate feasibility of label-free magnetic enrichment of erythrocyte fraction of CD34+ progenitor-derived cultures based on the presence of paramagnetic hemoglobin in the maturing erythrocytes. PMID:22952572

Jin, Xiaoxia; Abbot, Stewart; Zhang, Xiaokui; Kang, Lin; Voskinarian-Berse, Vanessa; Zhao, Rui; Kameneva, Marina V.; Moore, Lee R.; Chalmers, Jeffrey J.; Zborowski, Maciej

2012-01-01

291

Synthesis and characterization of magnetic hexacyanoferrate (II) polymeric nanocomposite for separation of cesium from radioactive waste solutions.  

PubMed

Nanocrystalline potassium zinc hexacyanoferrate loaded on nanoscale magnetite substrate was successfully synthesized for significantly enhanced removal of cesium from low-level radioactive wastes. A description was given for preparation and properties of these precursors. The physicochemical properties of these nanocomposites were determined using different techniques including Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), thermogravimetric analysis (TGA), scanning electron microscopy (SEM), and energy dispersive spectroscopy (EDS). Data clarified that supporting potassium zinc hexacyanoferrates on iron ferrite nanoparticles increased their thermal stability. Further, Fourier transform infrared spectra confirmed that the nanocomposites were well coordinated and incorporated in the polymer matrix. The average particle sizes, of these nanoparticles, determined by SEM had a good agreement with XRD results. Based on characterization data, the prepared zinc hexacyanoferrates were proposed to have a zeolitic rhombohedral structure with cavities can host alkali metal ions and water molecules. The magnetic analysis showed a super-paramagnetic behavior. Batch technique was applied to evaluate the influences of initial pH value, contact time, and competing cations on the efficiency of cesium removal. The sorption process was fast initially, and maximum separation was attained within 2h of contact. Cesium exchange was independent from pH value and deviate from ideal exchange phenomena. In neutral solutions, Cs(+) was retained through exchange with K(+); however, in acidic solution, phase transformation was proposed. Sorption capacity of these materials attained values amounted 1965 mg g(-1). The synthesized nanocomposites exhibited different affinities toward Cs(I), Co(II), and Eu(III) elements and showed a good ability to separate them from each other. PMID:23000210

Sheha, Reda R

2012-12-15

292

MAGNETIC DRUM SEPARATOR PERFORMANCE SCALPING SHREDDED TROMMEL OVERFLOW AT NOMINAL DESIGN CONDITIONS. TEST NO. 4.03, RECOVERY 1, NEW ORLEANS  

EPA Science Inventory

This report describes the first test of the shredded trommel overs magnetic drum separator at the New Orleans, Louisiana, resource recovery facility. Shredded trommel overs refers to waste which reports to the oversize discharge from the trommel and is subsequently shredded. For ...

293

Proceedings of the 22nd sensor symposium, Oct. 20-21, 2005, Tokyo, pp 125 -128 Micro Magnetic Separator for Stem Cell Sorting System  

E-print Network

Separator for Stem Cell Sorting System Hiromichi Inokuchi Yuji Suzuki Nobuhide Kasagi Naoki Shikazono sorting (uIMCS) system for ex- tracting stem cells from peripheral blood. In this report, micro magnetic, in which pluripotent stem cells extracted from a patient's body are cultured to differen- tiate

Kasagi, Nobuhide

294

Studies of the superconducting traveling wave cavity for high gradient LINAC  

E-print Network

Use of a traveling wave (TW) accelerating structure with a small phase advance per cell instead of standing wave may provide a significant increase of accelerating gradient in a superconducting linear accelerator. The TW section achieves an accelerating gradient 1.2-1.4 larger than TESLA-shaped standing wave cavities for the same surface electric and magnetic fields. Recent tests of an L-band single-cell cavity with a waveguide feedback demonstrated an accelerating gradient comparable to the gradient in a single-cell ILC-type cavity from the same manufacturer. This article presents the next stage of the 3- cell TW resonance ring development which will be tested in the traveling wave regime. The main simulation results of the microphonics and Lorentz Force Detuning (LFD) are also considered.

Avrakhov, Pavel; Kanareykin, Alexei; Solyak, Nikolay; Yakovlev, Vyacheslav P

2015-01-01

295

G-Quadruplex-based DNAzyme for colorimetric detection of cocaine: using magnetic nanoparticles as the separation and amplification element.  

PubMed

The appearance of the aptamer provides good recognition elements for small molecules, especially for drugs. In this work, by combining the advantages of magnetic nanoparticles (MNPs) with colorimetric drug detection using hemin-G-quadruplex complex as the sensing element, we report a simple and sensitive DNAzyme-based colorimetric sensor for cocaine detection in a 3,3,5,5-tetramethylbenzidine sulfate (TMB)-H(2)O(2) reaction system. The whole experimental processes are simplified. Cocaine aptamer fragments, SH-C2, are covalently labeled onto the amine-functionalized MNPs. When the target cocaine and another cocaine aptamer fragments (C1) grafted with G-riched strand AG4 (i.e. C1-AG4) are present simultaneously, the C2 layer on MNPs hybridizes partly with C1-AG4 to bind the cocaine. The C1-AG4 can be combinded with hemin to form DNAzyme which can effectively catalyze the H(2)O(2)-mediated oxidation of TMB, giving rise to a change in solution color. Importantly, using MNPs as the separation and amplification elements could effectively reduce the background signal and the interference from the real samples. A linear response from 0.1 ?M to 20 ?M is obtained for cocaine and a detection limit of 50 nM is achieved, which provides high sensitivity and selectivity to detect cocaine. PMID:21079882

Du, Yan; Li, Bingling; Guo, Shaojun; Zhou, Zhixue; Zhou, Ming; Wang, Erkang; Dong, Shaojun

2011-02-01

296

Electron Beam Characterization of a High-Gradient X-Band Photoinjector  

NASA Astrophysics Data System (ADS)

An X-band (8.548 GHz) rf photoinjector has been operated with a short pulse laser system to produce a high-brightness electron beam. The gun is designed to produce short (<1 ps) relativistic (5 MeV), low emittance (< ? mm-mrad, at 0.1 nC) electron bunches. The Ti:Sapphire laser system consists of a 12 fs oscillator and a 50 fs regenerative amplifier (Spitfire system from Positive Light) operating at a wavelength of 800 nm and a repetition rate of 1 kHz. The light is subsequently frequency tripled. Detailed experimental measurements of the e^- beam are planned, and the following diagnostics are available: 5 MeV magnetic spectrometer, 1 ps resolution visible streak camera, Cherenkov imaging system, matched Faraday cup, and quadrupole scan. A low-flux Compton scattering experiment is also under development which will help characterize the beam emittance and energy spread. This work was performed under the auspices of the DOE by LLNL under contract No. W-7405-ENG-48, and partially supported by NIH Contract No. N01-CO-97113 and AFOSR MURI Grant No. F49620-99-1-0297.

Gibson, D. J.; Hartemann, F. V.; Landahl, E. C.; Strong, F. W.; Troha, A. L.; Heritage, J. P.; Baldis, H. A.; Luhmann, N. C., Jr.; Ho, C. H.

2000-10-01

297

Development of High Gradient Superconducting Radio Frequency Cavities for International Linear Collider and Energy Recovery Linear Accelerator  

NASA Astrophysics Data System (ADS)

Superconducting radio frequency (SRF) cavities were used for storage rings like TRISTAN at KEK, HERA at DESY and LEP-II at CERN in 1990-2000. This technology has been accepted as a common accelerator technology. In August 2004, ITPR recommended an electron/positron linear collider based on SRF technology for the future high energy physics. ICFA accepted the recommendation and named it ILC (International Linear Collider). SRF cavities have a very unique feature due to its very small surface resistance. Energy recovery is another very exciting application. Many laboratories are proposing ERL (Energy Recovery LINAC) as a next bright photon source. In these accelerators, production of SRF cavities with reliably high performance is the most important issue. In this paper the activities of ILC high gradient cavities will be introduced. ERL activity will be briefly presented.

Saito, Kenji; Furuta, Fumio; Saeki, Takayuki

298

Wake fields from electron bunches in dielectric-lined waveguides, with applications to high-gradient acceleration and production of short-pulse radiation  

NASA Astrophysics Data System (ADS)

Excitation of wake fields from a short charge bunch moving parallel to the axis of a dielectric-lined cylindrical waveguide is analyzed. This situation amounts to generation of Cerenkov radiation in a transversely-bounded system. Wake fields are expanded into an orthonormal set of hybrid electric-magnetic (HEM) eigenfunctions for this waveguide geometry. The orthonormalization relations for this system are obtained, evidently for the first time, both for a stationary source and for a localized moving source such as a charge bunch; it is shown that these orthonormalization relations differ. Forces arising from wake fields are found, valid within and behind a distributed bunch. Deviation of bunch distribution from axisymmetry leads to generation of dipole modes of significant amplitude that may lead to instability. Poynting's theorem is examined for this system, and it is shown that convected Coulomb field energy must be subtracted from the Poynting flux to obtain the radiation power. This power, which balances drag on the bunch as calculated directly from the fields, is shown to flow in a direction opposite to that of the charge bunch. The results are easily generalized to bunches of arbitrary length and charge distribution, and to a train of such bunches. Numerical examples are presented for monopole, dipole and quadrupole wake field forces, and sample electric field patterns are shown to assist in understanding the unusual nature of this type of Cerenkov radiation. For a 2 nC rectangular drive bunch of length 0.20 mm, moving along the axis of an alumina-lined waveguide with inner and outer radii 0.50 mm and 5.0 mm, a peak accelerating gradient behind the bunch of 155 MeV/m is predicted. This relatively high magnitude of accelerating gradient suggests that a simple uniform dielectric pipe could be the basis for the structure of a future high-gradient electron/positron linear accelerator. The results of theoretical prediction will compared with ANL experiment.

Park, Soo Yong

2000-10-01

299

An integrated passive micromixer-magnetic separation-capillary electrophoresis microdevice for rapid and multiplex pathogen detection at the single-cell level.  

PubMed

Here we report an integrated microdevice consisting of an efficient passive mixer, a magnetic separation chamber, and a capillary electrophoretic microchannel in which DNA barcode assay, target pathogen separation, and barcode DNA capillary electrophoretic analysis were performed sequentially within 30 min for multiplex pathogen detection at the single-cell level. The intestine-shaped serpentine 3D micromixer provides a high mixing rate to generate magnetic particle-pathogenic bacteria-DNA barcode labelled AuNP complexes quantitatively. After magnetic separation and purification of those complexes, the barcode DNA strands were released and analyzed by the microfluidic capillary electrophoresis within 5 min. The size of the barcode DNA strand was controlled depending on the target bacteria (Staphylococcus aureus, Escherichia coli O157:H7, and Salmonella typhimurium), and the different elution time of the barcode DNA peak in the electropherogram allows us to recognize the target pathogen with ease in the monoplex as well as in the multiplex analysis. In addition, the quantity of the DNA barcode strand (?10(4)) per AuNP is enough to be observed in the laser-induced confocal fluorescence detector, thereby making single-cell analysis possible. This novel integrated microdevice enables us to perform rapid, sensitive, and multiplex pathogen detection with sample-in-answer-out capability to be applied for biosafety testing, environmental screening, and clinical trials. PMID:21870015

Jung, Jae Hwan; Kim, Gha-Young; Seo, Tae Seok

2011-10-21

300

Role of Nottingham and Thomson effects in heating of micro-protrusion in high-gradient accelerating structures  

NASA Astrophysics Data System (ADS)

It is widely accepted that one of the reasons for appearance of the RF breakdown which limits operation of high-gradient accelerating structures is the electron dark current [1]. This field emitted current, usually considered as a precursor of the breakdown, can be emitted from apexes of micro-protrusions on a structure surface. Therefore field and thermal processes in such protrusions deserve careful studies [2, 3]. The goal of our first study [3] was to analyze 2D process of RF field penetration inside protrusion of a metal with finite conductivity and to study corresponding Joule heating. In the current study, it is found that space charges can have a stabilizing effect on the electric field. We include a modification of the 1D model described in [4]. Moreover, we include into consideration, first, the Nottingham effect which may significantly change the protrusion heating. We also investigate the interplay between high temperature gradients and electric fields (Thomson heating).[4pt] [1] Wang and Loew, SLAC PUB 7684 October 1997.[0pt] [2] K.L. Jensen, Y.Y. Lau, D.W. Feldman, P.G. O'Shea, Phys. Rev. ST Accel. Beams 11, 081001(2008).[0pt] [3] Kashyn et al, AAC-2010.[0pt] [4] K.L. Jensen, J. LEbowitz, Y.Y. LAu, J. Luginsland, Journal of Applied Physics 111, 054917(2012).

Keser, Aydin; Nusinovich, Gregory; Kashyn, Dmytro; Antonsen, Thomas

2012-10-01

301

Preparation of Fe3O4@SiO2@layered double hydroxide core-shell microspheres for magnetic separation of proteins.  

PubMed

Three-component microspheres containing an SiO(2)-coated Fe(3)O(4) magnetite core and a layered double hydroxide (LDH) nanoplatelet shell have been synthesized via an in situ growth method. The resulting Fe(3)O(4)@SiO(2)@NiAl-LDH microspheres display three-dimensional core-shell architecture with flowerlike morphology, large surface area (83 m(2)/g), and uniform mesochannels (4.3 nm). The Ni(2+) cations in the NiAl-LDH shell provide docking sites for histidine and the materials exhibit excellent performance in the separation of a histidine (His)-tagged green fluorescent protein, with a binding capacity as high as 239 ?g/mg. The microspheres show highly selective adsorption of the His-tagged protein from Escherichia coli lysate, demonstrating their practical applicability. Moreover, the microspheres possess superparamagnetism and high saturation magnetization (36.8 emu/g), which allows them to be easily separated from solution by means of an external magnetic field and subsequently reused. The high stability and selectivity of the Fe(3)O(4)@SiO(2)@NiAl-LDH microspheres for the His-tagged protein were retained over several separation cycles. Therefore, this work provides a promising approach for the design and synthesis of multifunctional LDH microspheres, which can be used for the practical purification of recombinant proteins, as well as having other potential applications in a variety of biomedical fields including drug delivery and biosensors. PMID:22191643

Shao, Mingfei; Ning, Fanyu; Zhao, Jingwen; Wei, Min; Evans, David G; Duan, Xue

2012-01-18

302

Yolk-shell nanostructured Fe3O4@NiSiO3 for selective affinity and magnetic separation of His-tagged proteins.  

PubMed

Recent developments of nanotechnology encourage novel materials for facile separations and purifications of recombinant proteins, which are of great importance in disease diagnoses and treatments. We find that Fe3O4@NiSiO3 with yolk-shell nanostructure can be used to specifically purify histidine-tagged (His-tagged) proteins from mixtures of lysed cells with a recyclable process. Each individual nanoparticle composes by a mesoporous nickel silicate shell and a magnetic Fe3O4 core in the hollow inner, which is featured by its great loading efficiency and rapid response toward magnetic fields. The abundant Ni(2+) cations on the shell provide docking sites for selective coordination of histidine and the reversible release is induced by excess imidazole solution. Because of the Fe3O4 cores, the separation, concentration, and recycling of the nanocomposites become feasible under the controls of magnets. These characteristics would be highly beneficial in nanoparticle-based biomedical applications for targeted-drug delivery and biosensors. PMID:25303145

Wang, Yang; Wang, Guangchuan; Xiao, Yun; Yang, Yuling; Tang, Ruikang

2014-11-12

303

A novel magnetically separable TiO{sub 2}/CoFe{sub 2}O{sub 4} nanofiber with high photocatalytic activity under UV-vis light  

SciTech Connect

Graphical abstract: A novel magnetically separable composite photocatalyst TiO{sub 2}/CoFe{sub 2}O{sub 4} nanofiber was prepared by sol-gel method and electrospinning technique, which can be reclaimed with a magnet, and the decolorizing efficiency of MB solution reached 95.87%. Highlights: Black-Right-Pointing-Pointer The composite TiO{sub 2}/CoFe{sub 2}O{sub 4} nanofibers with diameter of 110 {+-} 28 nm have been successfully synthesized by the combination of sol-gel method and electrospinning technique. Black-Right-Pointing-Pointer The presence of Co{sup 2+} or/and Fe{sup 3+} ions may occupy some of the lattice sites of TiO{sub 2} to form an iron-titanium solid solution and narrow the band gap, which broadens the response region of visible light. Black-Right-Pointing-Pointer The resultant nanofibers not only have high decomposition efficiency with methylene blue (MB) under the UV irradiation, which is close to that of Degussa P25, but also can be separated with a magnet and avoid the secondary pollution of the treated water. -- Abstract: A novel magnetically separable heterogeneous photocatalyst TiO{sub 2}/CoFe{sub 2}O{sub 4} nanofiber was prepared by sol-gel method and electrospinning technology, followed by heat treatment at 550 Degree-Sign C for 2 h. The phase structure, morphology and magnetic property of the composite nanofibers were characterized by X-ray diffraction, scanning electron microscopy, transmission electron microscope and vibrating sample magnetometer analysis. The photocatalytic studies of TiO{sub 2}/CoFe{sub 2}O{sub 4} fibers suggested that the presence of CoFe{sub 2}O{sub 4} not only enhanced the absorbance of UV light, but also broadened the response region to visible light. The decolorizing efficiency of methylene blue (MB) solution reaches 95.87% over TiO{sub 2}/CoFe{sub 2}O{sub 4} nanofibers under 300 W Hg lamp after 5 h, which is close to that of Degussa P25. Furthermore, these fibers can be collected with a magnet for reuse and effectively avoid the secondary pollution of the treated water.

Li, Cong-Ju, E-mail: congjuli@gmail.com [Beijing Key Laboratory of Clothing Materials R and D and Assessment, Beijing Institute of Fashion Technology, Beijing 100029 (China)] [Beijing Key Laboratory of Clothing Materials R and D and Assessment, Beijing Institute of Fashion Technology, Beijing 100029 (China); Wang, Jiao-Na; Wang, Bin [Beijing Key Laboratory of Clothing Materials R and D and Assessment, Beijing Institute of Fashion Technology, Beijing 100029 (China)] [Beijing Key Laboratory of Clothing Materials R and D and Assessment, Beijing Institute of Fashion Technology, Beijing 100029 (China); Gong, Jian Ru, E-mail: gongjr@nanoctr.cn [National Center for Nanoscience and Technology, China, 11 Zhongguancun Beiyitiao, Beijing 100190 (China); Lin, Zhang [Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fujian 350002 (China)] [Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fujian 350002 (China)

2012-02-15

304

Insights into the capillary electrophoresis separation of heparin disaccharides from nuclear magnetic resonance, pKa, and electrophoretic mobility measurements.  

PubMed

Determination of the pK(a) values of heparin disaccharide functional groups can provide insights into the nature of glycosaminoglycan (GAG)-protein interactions and prove useful for optimization of the charged-based separations typically used in GAG analysis. In order to gain a better understanding into the capillary electrophoresis (CE) separation process, the pK(a) values of the carboxylate and primary amine moieties of 11 heparin disaccharide standards were determined through (1)H NMR detected pH titrations. These pK(a) values were used to calculate the effective net charge of each disaccharide and compared to the electrophoretic mobilities measured by CE. Although a different migration order had been reported by other researchers, our results indicate a strong positive correlation between the two measurements, consistent with the migration order observed in our CE separations. The effect of mutarotation was also examined by (1)H NMR. Mutarotation equilibrium constants favored the alpha anomer over the beta conformation. pK(a) values determined for both anomers of the four disaccharide standards containing a GlcN primary amine indicated that the beta anomer of the GlcN residue was more acidic. Partial separation of these anomers was achieved in CE separations using either formic acid or phosphate buffer. PMID:19653663

Eldridge, Stacie L; Higgins, Layne A; Dickey, Bailey J; Larive, Cynthia K

2009-09-01

305

Hybrid and transflective system based on digital holographic microscope and low coherent interferometer for high gradient shape measurement  

NASA Astrophysics Data System (ADS)

The most suited techniques for quantitative and accurate determination of the phase distribution in a phase photonic microstructures are based on the interferometry, especially the digital holography (DH) in microscopic configuration. However there is well known limitation of the coherent full- field interferometric measurements: the phase difference between the neighboring samples cannot be larger than 2?, or objects shape have to generate light that can be collected by used optical system. This limitation might be overcame by use of a well-known technique called low-coherence interferometry (LCI) which allows for absolute shape measurements with a nanometer resolution and does not have 2? limitation of coherent interferometric techniques. In this work a dual channel measurement system for characterization of a high numerical aperture objects is presented. The system combines functionalities of the LCI system based on Twyman-Green configuration and the DHM system based on Mach-Zehnder configuration. The DHM allows to measure sample in transmission while LCI setup provides reflective measurement data and, therefore, provides a more complete tool for topography characterization. In presented paper we focus on the measurement of high gradient objects were both methods fail if applied independently: the LCI gives measurement only in the object area of low NA while the DHM cannot provide absolute shape characterization due to limited NA of imaging system. The dual channel system extends capabilities of both methods. In our paper we present experimental results for topography measurement of high NA microlenses. The accuracy of the development method is discussed and both simulation and experimental data are provided.

Li?ewski, K.; Tomczewski, S.; Kostencka, J.; Kozacki, T.

2013-04-01

306

Nonlinear magnetic response from the Ru0.9Sr2YCu2.1O7.9 magnetosuperconductor and its resultant phase separation  

NASA Astrophysics Data System (ADS)

We investigated the third harmonic nonlinear susceptibility of the Ru0.9Sr2YCu2.1O7.9 magnetosuperconductor and found the presence of two well separated negative peaks. The peak at TM=140K is connected to the previously well known main magnetic ordering of the Ru sublattice, and the peak at around 180K is probably associated with the formation of superparamagnetic particles above TM. The negative signals for both peaks will be discussed in terms of ensuing magnetic orderings of Ru spins at these temperatures. Further, these results will be compared with a recent study of nonlinear susceptibility on RuSr2GdCu2O8.

Živkovi?, I.; Awana, V. P. S.; Kishan, H.; Balamurugan, S.; Takayama-Muromachi, E.; Felner, I.

2007-05-01

307

Separation of the contributions to the magnetization of Tm{sub 1-x}Yb{sub x}B{sub 12} solid solutions in steady and pulsed magnetic fields  

SciTech Connect

The magnetization of substitutional Tm{sub 1-x}Yb{sub x}B{sub 12} solid solutions is studied in the composition range 0 < x {<=} 0.81. The measurements are performed at low temperatures (1.9-300 K) in steady (up to 11 T) and pulsed (up to 50 T, pulse duration of 20-100 ms) magnetic fields. An analysis of the experimental data allowed the contributions to the magnetization of the paramagnetic phase of the Tm{sub 1-x}Yb{sub x}B{sub 12} compounds to be separated. These contributions include a Pauli component, which corresponds to the response of the heavy-fermion manybody states that appears in the energy gap in the vicinity of the Fermi level (density of states (3-4) Multiplication-Sign 10{sup 21} cm{sup -3} meV{sup -1}), and a contribution with saturation in high magnetic fields attributed to the localized magnetic moments ((0.8-3.7){mu}{sub B} per unit cell) of the nanoclusters formed by rare-earth ions with an antiferromagnetic interaction.

Bogach, A. V., E-mail: alex@lt.gpi.ru; Sluchanko, N. E.; Glushkov, V. V.; Demishev, S. V.; Azarevich, A. N.; Filippov, V. B. [Russian Academy of Sciences, Prokhorov General Physics Institute (Russian Federation); Shitsevalova, N. Yu.; Levchenko, A. V. [National Academy of Sciences of Ukraine, Institute of Problems of Materials Science (Ukraine); Vanacken, J.; Moshchalkov, V. V. [Katholieke Universiteit Leuven, Institute of Nanoscale Physics and Chemistry (Belgium); Gabani, S.; Flachbart, K. [Slovak Academy of Sciences, Institute of Experimental Physics (Slovakia)

2013-05-15

308

Phase-separation-induced changes in the magnetic and transport properties of the quaternary Heusler alloy Co2Mn1-xTixSn  

NASA Astrophysics Data System (ADS)

The quaternary Heusler compound Co2Mn1-xTixSn with x=0 , 0.2, 0.4, 0.5, 0.6, 0.8, and 1 shows a phase separation into the two Heusler compounds, Co2MnSn and Co2TiSn . Only at the edges of the composition range a slight admixture of Mn and Ti to the respective other phase is observed. This phase separation leads to a distinct microstructure which can be altered by the composition of the material. Pronounced changes in the magnetic and electronic properties take place with varying composition. Two magnetic transitions occur which indicate different Curie temperatures for both phases. The reduction in the thermal lattice conductivity is of particular interest for an optimization of Heusler compounds for thermoelectric applications. In the field of spintronics the use of superlattices composed of Co2MnSn and Co2TiSn without any interlayer diffusion is suggested.

Graf, Tanja; Barth, Joachim; Blum, Christian G. F.; Balke, Benjamin; Felser, Claudia; Klaer, Peter; Elmers, Hans-Joachim

2010-09-01

309

Relationship of bed and bank resistance to total flow resistance in a high gradient stream, Fraser Experimental Forest, Colorado, USA  

NASA Astrophysics Data System (ADS)

The relative influence of bank resistance versus bed resistance on the total flow resistance in a high gradient system has been a source of debate, but because of the difficulty of making measurements in these systems has rarely been explored. Nine step-pool and five cascade reaches were surveyed over five stages in Fraser Experimental Forest, Colorado, using a combination of a laser theodolite and LiDAR (Light Detection and Ranging). The LiDAR was used to capture banks and channel geometry at low flows, whereas the water surface and bed data were collected with the laser theodolite at both low and high flows. Reach-averaged mean velocity was measured using fluorometers and Rhodamine WT dye tracers. The roughness created by the bed and banks were calculated using the standard deviation of the residuals of a longitudinal profile regression (?bank and ?bed). In addition, hyperspectral and spectral analysis are used to characterize the bed, banks, and water surface during both base and bankfull flows. The three methods of characterizing the roughness created by the bed and banks are used to ascertain relative influence of the banks versus the bed on total flow resistance. These data are used to evaluate three hypotheses: i) step-pool bed morphology has a distinctively different spectral signature than cascade bed morphology; ii) the bed and bank resistance can be evaluated using either standard deviation of the residuals or by hyperspectral analysis and related to total flow resistance; iii) potential controls on bank resistance include both gradient and grain size, which differ based on channel type (step-pool versus cascade). Preliminary results indicate that both step-pool and cascade channel morphologies can be evaluated using spectral analysis despite the short reach lengths (? 30 m). Evaluation of ?bed indicated that there is no significant difference between means for step-pool (0.145) versus cascade (0.163) reaches, but the boxplots show a greater variability in the values of ?bed for step-pool reaches. Furthermore, there was no significant difference in the value of ?bank for step-pool (0.656) versus cascade (0.692) reaches. Both gradient and grain size are significant controls of ?bank. The larger grain sizes led to higher values of ?bank, most likely from larger boulders forcing flows towards the banks creating an irregular pattern of erosion. At bank filling flows the bank resistance was found to be significantly related to total flow resistance, with flow resistance increasing as ?bank increased.

David, G. C.; Wohl, E. E.; Yochum, S. E.

2010-12-01

310

Sonochemical synthesis and characterization of magnetic separable Fe3O4–TiO2 nanocomposites and their catalytic properties  

Microsoft Academic Search

A novel sonochemical method is described for the preparation of Fe3O4–TiO2 photocatalysts in which nanocrystalline titanium dioxide particles are directly coated onto a magnetic core. The Fe3O4 nanoparticles were partially embedded in TiO2 agglomerates. TiO2 nanocrystallites were obtained by hydrolysis and condensation of titanium tetraisopropyl in the presence of ethanol and water under high-intensity ultrasound irradiation. This method is attractive

Wanquan Jiang; Xueping Zhang; Xinglong Gong; Fangfang Yan; Zhong Zhang

2010-01-01

311

The general concept of signal–noise separation (SNS): mathematical aspects and implementation in magnetic resonance spectroscopy  

Microsoft Academic Search

Magnetic resonance spectroscopy (MRS) and spectroscopic imaging (MRSI) are increasingly recognized as potentially key modalities\\u000a in cancer diagnostics. It is, therefore, urgent to overcome the shortcomings of current applications of MRS and MRSI. We explain\\u000a and substantiate why more advanced signal processing methods are needed, and demonstrate that the fast Padé transform (FPT),\\u000a as the quotient of two polynomials, is

Dževad Belki?; Karen Belki?

2009-01-01

312

Fabrication of magnetically separable fluorescent terbium-based MOF nanospheres for highly selective trace-level detection of TNT.  

PubMed

In this work, we present novel kinds of Fe3O4@Tb-BTC magnetic metal-organic framework (MOF) nanospheres which possess both magnetic characteristics and fluorescent properties using a layer by layer assembly technique. The structure and morphology of the as-prepared Fe3O4@Tb-BTC were systematically characterized and it was applied in detection of nitroaromatic explosives, such as 2,4-dinitrotoluene (2,4-DNT), 2,6-dinitrotoluene (2,6-DNT), 2-nitrotoluene (2-NT), 4-nitrotoluene (4-NT), nitrobenzene (NB) and picric acid (PA). The results indicate that the fluorescence intensity of Fe3O4@Tb-BTC can be quenched by all analytes studied in the present work. Remarkably, the as-synthesized nanospheres exhibit high sensitivity for 2,4,6-trinitrotoluene (TNT) detection with Ksv value of (94?800 M(-1)). Besides, the magnetic nanospheres can be easily recycled, which makes it more convenient for reutilization and friendly to the environment. The results show that it has broad application prospects in the detection of nitroaromatic explosives. PMID:24452313

Qian, Jing-Jing; Qiu, Ling-Guang; Wang, Yi-Min; Yuan, Yu-Peng; Xie, An-Jian; Shen, Yu-Hua

2014-03-14

313

Phase separation and suppression of the structural and magnetic transitions in superconducting doped iron tellurides, Fe(1+x)Te(1-y)S(y).  

PubMed

Single crystal and powder samples of the series of iron chalcogenide superconductors with nominal composition, Fe((1.15))Te((1-)y)S(y), are found to form for 0 ? y ? 0.15. They crystallize in the tetragonal anti-PbO structure, which is composed of layers of edge-shared Fe(Te, S)(4) tetrahedra. For y = 0, Fe(1+x)Te (x ? 0.12(1)) is nonsuperconducting and undergoes a tetragonal (P4/nmm) to monoclinic (P2(1)/m) structural transition at ?65 K, associated with the onset of commensurate antiferromagnetic order at q = (0.5 0 0.5). We show that on sulfur substitution, Fe(1+x)Te(1-y)S(y) becomes orthorhombic (Pmmn) at low temperature for 0 ? y ? 0.015, where the greatly suppressed magnetic scattering is now incommensurate at q = (0.5-? 0 0.5) and possesses short ranged magnetic correlations that are well fitted with a two-dimensional Warren peak shape. At much higher concentrations of S (y ? 0.075), there is suppression of both the structural and magnetic transitions and a superconducting transition at 9 K is observed. Between these two composition regimes, there exists a region of phase separation (0.025 ? y ? 0.05), where the low temperature neutron diffraction data is best refined with a model containing both the tetragonal and orthorhombic phases. The increase in the amount of sulfur is found to be associated with a reduction in interstitial iron, x. Microprobe analysis of a single crystal of composition Fe((1.123(5)))Te((0.948(4)))S((0.052(4))) confirms the presence of compositional variation within the crystals, rationalizing the observed phase separation. PMID:20806923

Zajdel, Pawel; Hsieh, Ping-Yen; Rodriguez, Efrain E; Butch, Nicholas P; Magill, Jeff D; Paglione, Johnpierre; Zavalij, Peter; Suchomel, Matthew R; Green, Mark A

2010-09-22

314

Dried calcium alginate/magnetite spheres: a new support for chromatographic separations and enzyme immobilization  

SciTech Connect

Dried spheres made from an alginate solution containing magnetite particles have excellent potential as a support for enzyme immobilization and chromatographic applications. The beads were found to be much stronger than gels such as polyacrylamide and dextran, indicating that high flow rates and pressures could be used in column separations. The support withstood not only temperatures of up to 120/sup 0/C, but also most pH values and common solvents. While some solutions, such as phosphate buffers, dissolved the spheres, stabilization with Tyzor TE eliminated this problem. The physical properties of the beads include a glasslike density of 2.2 g/mL, excellent sphericity, low porosity, and a narrow size distribution. The magnetite present in the support allows the beads to be used for magnetic separations such as high gradient magnetic filtration. Their high degree of microroughness provides a large exposed surface area for enzyme and ligand binding. Mixed Actinomyces fradiae proteases and Aspergillus niger ..cap alpha..-amylase, two enzymes representative of classes which attack large substrates, were immobilized on the bead's surface with high activity and stability. A cyanuric dye which can be used in chromatographic applications (Cibacron Blue F3GA) was also readily coupled to the surface of this support with good yield.

Burns, M.A.; Kvesitadze, G.I.; Graves, D.J.

1985-02-01

315

Using shell-tunable mesoporous Fe3O4@HMS and magnetic separation to remove DDT from aqueous media.  

PubMed

1,1-bis(4-chlorophenyl)-2,2,2-trichloroethane (DDT) is of concern in water treatment because of its persistence and health effects. A new concept is proposed to synthesize hexagonal mesoporous silica (HMS) with magnetic functionalization for DDT removal from aqueous media. Fe(3)O(4) nanocrystals were synthesized by a low-temperature solvothermal process, and then encapsulated in mesoporous silica through a packing approach, forming core-shell structured Fe(3)O(4)@HMS microspheres. The synthesized materials were characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM) and nitrogen adsorption-desorption techniques. The results indicate that the silica shell conserves mesoporous structure after the removal of surfactant templates. Different from previous studies, the thickness, pore volume and surface area of silica shell can be controlled by adjusting the reaction condition. These Fe(3)O(4)@HMS materials show high adsorption capacity and fast adsorption rate for DDT. Because of the useful magnetic property and unique mesoporous structure, the synthesized materials provide a fast, convenient and highly efficient means to remove DDT from aqueous media. PMID:19586720

Tian, Hua; Li, Jinjun; Shen, Qun; Wang, Hailin; Hao, Zhengping; Zou, Linda; Hu, Qin

2009-11-15

316

Drive tube 60009 - A chemical study of magnetic separates of size fractions from five strata. [lunar soil analysis  

NASA Technical Reports Server (NTRS)

Each bulk soil and both the magnetic and nonmagnetic components of the 90-150 micron and below 20 micron fractions of five soils from drive tube 60009 were analyzed. Samples were analyzed for FeO, Na2O, Sc, Cr, Co, Ni, Hf, Ta, Th, La, Ce, Sm, Eu, Tb, Yb, and Lu by neutron activation analysis. Several samples were fused and analyzed for major elements by electron microprobe analysis. Compositional variations are not systematically related to depth. The compositions of the five soils studied are well explained by a two-component mixing model whose end members are a submature Apollo 16-type soil and an extremely immature anorthositic material similar to 60025. There is evidence that the anorthositic component had received a small amount of exposure before these soils were mixed. After mixing, the soils received little exposure suggesting mixing and deposition on a rapid time scale.

Blanchard, D. P.; Jacobs, J. W.; Brannon, J. C.; Brown, R. W.

1976-01-01

317

Fe{sub 3}O{sub 4}@graphene oxide composite: A magnetically separable and efficient catalyst for the reduction of nitroarenes  

SciTech Connect

Highlights: ? The Fe{sub 3}O{sub 4}@GO composite was prepared by a facile co-precipitation method. ? Fe{sub 3}O{sub 4} nanoparticles are well distributed on GO nanosheets. ? Fe{sub 3}O{sub 4}@GO was for the first time explored as a catalyst to reduce nitroarenes. ? Fe{sub 3}O{sub 4}@GO exhibits higher catalytic activity. ? The composite catalyst is easily recycled due to its magnetic separability. - Abstract: We reported a facile co-precipitation method to prepare a highly active Fe{sub 3}O{sub 4}@graphene oxide (Fe{sub 3}O{sub 4}@GO) composite catalyst, which was fully characterized by means of X-ray diffraction (XRD), Fourier transformed infrared (FTIR) spectroscopy, transmission electron microscopy (TEM) and N{sub 2} adsorption–desorption measurements. The results demonstrated that the Fe{sub 3}O{sub 4} nanoparticles (Fe{sub 3}O{sub 4} NPs) with a small diameter of around 12 nm were densely and evenly deposited on the graphene oxide (GO) sheets. The as-prepared Fe{sub 3}O{sub 4}@GO composite was explored as a catalyst to reduce a series of nitroarenes for the first time, which exhibited a great activity with a turnover frequency (TOF) of 3.63 min{sup ?1}, forty five times that of the commercial Fe{sub 3}O{sub 4} NPs. The dosages of catalyst and hydrazine hydrate are both less than those reported. Furthermore, the composite catalyst can be easily recovered due to its magnetic separability and high stability.

He, Guangyu [Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, Changzhou University, Jiangsu Province, Changzhou 213164 (China); Key Laboratory of Ministry of Education for Soft Chemistry and Functional Materials, Nanjing University of Science and Technology, Nanjing 210094 (China); Liu, Weifeng; Sun, Xiaoqiang [Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, Changzhou University, Jiangsu Province, Changzhou 213164 (China); Chen, Qun, E-mail: chenqunjpu@yahoo.com [Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, Changzhou University, Jiangsu Province, Changzhou 213164 (China); Wang, Xin [Key Laboratory of Ministry of Education for Soft Chemistry and Functional Materials, Nanjing University of Science and Technology, Nanjing 210094 (China); Chen, Haiqun, E-mail: hqchenyf@hotmail.com [Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, Changzhou University, Jiangsu Province, Changzhou 213164 (China)

2013-05-15

318

Magnetism  

NSDL National Science Digital Library

This webpage is part of the University Corporation for Atmospheric Research (UCAR) Windows to the Universe program. It describes the nature and configuration of magnetic fields, which are the result of moving electric charges, including how they cause magnetic objects to orient themselves along the direction of the magnetic force points, which are illustrated as lines. Magnetic field lines by convention point outwards at the north magnetic pole and inward at the south magnetic pole. The site features text, scientific illustrations and an animation. Text and vocabulary are selectable for the beginning, intermediate, or advanced reader.

Team, University C.

2007-12-12

319

Optimization of a phase separation based magnetic-stirring salt-induced liquid-liquid microextraction method for determination of fluoroquinolones in food.  

PubMed

Herein, we developed a novel integrated apparatus to perform phase separation based on magnetic-stirring, salt-induced, liquid-liquid microextraction for determination of five fluoroquinolones in animal-based foods by HPLC analysis. The novel integrated apparatus consisted of three simple HDPE (high density polyethylene) parts that were used to separate the solvent from the aqueous solution prior to retrieving the extractant. The extraction parameters were optimized using the response surface method based on central composite design: 791?L of acetone solvent, 2.5g of Na2SO4, pH 1.7, 3.0min of stir time, and 5.5min centrifugation. The limits of detection were 0.07-0.53?gkg(-1) and recoveries were 91.6-105.0% for the five fluoroquinolones from milk, eggs and honey. This method is easily constructed from inexpensive materials, extraction efficiency is high, and the approach is compatible with HPLC analysis. Thus, it has excellent prospects for sample pre-treatment and analysis of fluoroquinolones in animal-based foods. PMID:25577068

Gao, Ming; Wang, Huili; Ma, Meiping; Zhang, Yuna; Yin, Xiaohan; Dahlgren, Randy A; Du, Dongli; Wang, Xuedong

2015-05-15

320

Ionic liquid coated magnetic core/shell Fe3O4@SiO2 nanoparticles for the separation/analysis of linuron in food samples  

NASA Astrophysics Data System (ADS)

Three hydrophobic ionic liquids (ILs) including 1-butyl-3-methylimidazole hexafluorophosphate ([BMIM]PF6), 1-hexyl-3-methyl-imidazole hexafluorophosphate ([HMIM]PF6), and 1-octyl-3-methylimidazole hexafluoro-phosphate ([OMIM]PF6) coated Fe3O4@SiO2 nanoparticles with core-shell structure to prepare magnetic solid phase extraction agent (Fe3O4@SiO2@ILs) and establish a new method of magnetic solid phase extraction (MSPE) coupled with UV spectrometry for separation/analysis of linuron. The results showed that linuron was adsorbed rapidly by Fe3O4@SiO2@[OMIM]PF6 and eluanted by ethanol. Under the optimal conditions, preconcentration factor of the proposed method was 10-fold. The linear range, detection limit, correlation coefficient (R) and relative standard deviation (RSD) were found to be 0.04-20.00 ?g mL-1, 5.0 ng mL-1, 0.9993 and 2.8% (n = 3, c = 4.00 ?g mL-1), respectively. The Fe3O4@SiO2 nanoparticles could be used repeatedly for 10 times. This proposed method has been successfully applied to the determination of linuron in food samples.

Chen, Jieping; Zhu, Xiashi

2015-02-01

321

High-gradient near-quench-limit operation of superconducting Tesla-type cavities in scope of the International Linear Collider  

NASA Astrophysics Data System (ADS)

We report the successful demonstration of an ILC-like high-gradient near-quench-limit operation at the Superconducting RF Test Facility at the High Energy Accelerator Research Organization (KEK) in Japan. Preparation procedures necessary for the accelerator operation were conducted, such as rf phase calibration, beam-based gradient calibration, and automated beam compensation. Test runs were performed successfully for nominal operation, high-loaded Q (QL) operation, and automated PkQL operation. The results are described in terms of the achieved precision and stabilities of gradients and phases.

Omet, Mathieu; Hayano, Hitoshi; Kuramoto, Ayaka; Matsumoto, Toshihiro; Michizono, Shinichiro; Miura, Takako; Qiu, Feng

2014-07-01

322

Magnetism  

NSDL National Science Digital Library

This radio broadcast discusses the history of magnetism from the time of its discovery by an apocryphal Greek sheperd until the late 16th century and the work of William Gilbert. There is also discussion of who pioneered the study of magnetism, what theories they constructed from its curious abilities, and how the power of the magnet was brought out of the realm of magic and into the service of science. The broadcast concludes with a discussion of why magnetism is still mysterious and how the modern search for the single magnetic pole, or magnetic monopole, could provide a fundamental unit of magnetism, essential for ultimate explanation. The broadcast is 41 minutes and 45 seconds in length.

323

Dry superconducting magnetic cleaning of pulverized coal  

Microsoft Academic Search

There are wet and dry methods of cleaning pulverized coal for thermal power stations. However, it may be desirable to use a dry process because dewatering finely pulverized coal is difficult and expensive, and burning wet coal reduces the thermal efficiency of the combustion process. It has been shown that high gradient magnetic filters can be constructed which will extract

S. Zhou; E. S. Garbett; R. F. Boucher

1996-01-01

324

Ultracapacitor separator  

DOEpatents

An ultracapacitor includes two solid, nonporous current collectors, two porous electrodes separating the collectors, a porous separator between the electrodes and an electrolyte occupying the pores in the electrodes and separator. The electrolyte is a polar aprotic organic solvent and a salt. The porous separator comprises a wet laid cellulosic material.

Wei, Chang (Niskayuna, NY); Jerabek, Elihu Calvin (Glenmont, NY); LeBlanc, Jr., Oliver Harris (Schenectady, NY)

2001-03-06

325

Size-regulated group separation of CoFe2O4 nanoparticles using centrifuge and their magnetic resonance contrast properties  

PubMed Central

Magnetic nanoparticle (MNP)-based magnetic resonance imaging (MRI) contrast agents (CAs) have been the subject of extensive research over recent decades. The particle size of MNPs varies widely and is known to influence their physicochemical and pharmacokinetic properties. There are two commonly used methods for synthesizing MNPs, organometallic and aqueous solution coprecipitation. The former has the advantage of being able to control the particle size more effectively; however, the resulting particles require a hydrophilic coating in order to be rendered water soluble. The MNPs produced using the latter method are intrinsically water soluble, but they have a relatively wide particle size distribution. Size-controlled water-soluble MNPs have great potential as MRI CAs and in cell sorting and labeling applications. In the present study, we synthesized CoFe2O4 MNPs using an aqueous solution coprecipitation method. The MNPs were subsequently separated into four groups depending on size, by the use of centrifugation at different speeds. The crystal shapes and size distributions of the particles in the four groups were measured and confirmed by transmission electron microscopy and dynamic light scattering. Using X-ray diffraction analysis, the MNPs were found to have an inverse spinel structure. Four MNP groups with well-selected semi-Gaussian-like diameter distributions were obtained, with measured T2 relaxivities (r2) at 4.7 T and room temperature in the range of 60 to 300 mM?1s?1, depending on the particle size. This size regulation method has great promise for applications that require homogeneous-sized MNPs made by an aqueous solution coprecipitation method. Any group of the CoFe2O4 MNPs could be used as initial base cores of MRI T2 CAs, with almost unique T2 relaxivity owing to size regulation. The methodology reported here opens up many possibilities for biosensing applications and disease diagnosis. PACS 75.75.Fk, 78.67.Bf, 61.46.Df PMID:24004536

2013-01-01

326

Size-regulated group separation of CoFe2O4 nanoparticles using centrifuge and their magnetic resonance contrast properties.  

PubMed

Magnetic nanoparticle (MNP)-based magnetic resonance imaging (MRI) contrast agents (CAs) have been the subject of extensive research over recent decades. The particle size of MNPs varies widely and is known to influence their physicochemical and pharmacokinetic properties. There are two commonly used methods for synthesizing MNPs, organometallic and aqueous solution coprecipitation. The former has the advantage of being able to control the particle size more effectively; however, the resulting particles require a hydrophilic coating in order to be rendered water soluble. The MNPs produced using the latter method are intrinsically water soluble, but they have a relatively wide particle size distribution. Size-controlled water-soluble MNPs have great potential as MRI CAs and in cell sorting and labeling applications. In the present study, we synthesized CoFe2O4 MNPs using an aqueous solution coprecipitation method. The MNPs were subsequently separated into four groups depending on size, by the use of centrifugation at different speeds. The crystal shapes and size distributions of the particles in the four groups were measured and confirmed by transmission electron microscopy and dynamic light scattering. Using X-ray diffraction analysis, the MNPs were found to have an inverse spinel structure. Four MNP groups with well-selected semi-Gaussian-like diameter distributions were obtained, with measured T2 relaxivities (r2) at 4.7 T and room temperature in the range of 60 to 300 mM-1s-1, depending on the particle size. This size regulation method has great promise for applications that require homogeneous-sized MNPs made by an aqueous solution coprecipitation method. Any group of the CoFe2O4 MNPs could be used as initial base cores of MRI T2 CAs, with almost unique T2 relaxivity owing to size regulation. The methodology reported here opens up many possibilities for biosensing applications and disease diagnosis. PACS: 75.75.Fk, 78.67.Bf, 61.46.Df. PMID:24004536

Kang, Jongeun; Lee, Hyunseung; Kim, Young-Nam; Yeom, Areum; Jeong, Heejeong; Lim, Yong Taik; Hong, Kwan Soo

2013-01-01

327

Size-regulated group separation of CoFe2O4 nanoparticles using centrifuge and their magnetic resonance contrast properties  

NASA Astrophysics Data System (ADS)

Magnetic nanoparticle (MNP)-based magnetic resonance imaging (MRI) contrast agents (CAs) have been the subject of extensive research over recent decades. The particle size of MNPs varies widely and is known to influence their physicochemical and pharmacokinetic properties. There are two commonly used methods for synthesizing MNPs, organometallic and aqueous solution coprecipitation. The former has the advantage of being able to control the particle size more effectively; however, the resulting particles require a hydrophilic coating in order to be rendered water soluble. The MNPs produced using the latter method are intrinsically water soluble, but they have a relatively wide particle size distribution. Size-controlled water-soluble MNPs have great potential as MRI CAs and in cell sorting and labeling applications. In the present study, we synthesized CoFe2O4 MNPs using an aqueous solution coprecipitation method. The MNPs were subsequently separated into four groups depending on size, by the use of centrifugation at different speeds. The crystal shapes and size distributions of the particles in the four groups were measured and confirmed by transmission electron microscopy and dynamic light scattering. Using X-ray diffraction analysis, the MNPs were found to have an inverse spinel structure. Four MNP groups with well-selected semi-Gaussian-like diameter distributions were obtained, with measured T2 relaxivities ( r 2) at 4.7 T and room temperature in the range of 60 to 300 mM-1s-1, depending on the particle size. This size regulation method has great promise for applications that require homogeneous-sized MNPs made by an aqueous solution coprecipitation method. Any group of the CoFe2O4 MNPs could be used as initial base cores of MRI T2 CAs, with almost unique T2 relaxivity owing to size regulation. The methodology reported here opens up many possibilities for biosensing applications and disease diagnosis.

Kang, Jongeun; Lee, Hyunseung; Kim, Young-Nam; Yeom, Areum; Jeong, Heejeong; Lim, Yong Taik; Hong, Kwan Soo

2013-09-01

328

A revised velocity-reversal and sediment-sorting model for a high-gradient, pool-riffle stream  

USGS Publications Warehouse

Sediment-sorting processes related to varying channel-bed morphology were investigated from April to November 1993 along a 1-km pool-riffle and step-pool reach of North Saint Vrain Creek, a small mountain stream in the Rocky Mountains of northern Colorado. Measured cross-sectional areas of flow were used to suggest higher velocities in pools than in riffles at high flow. Three hundred and sixteen tracer particles, ranging in size from 16 mm to 256 mm, were placed in two separate pool-riffle-pool sequences and used to assess sediment-sorting patterns and sediment-transport competence variations. Tracer-particle depositional evidence indicated higher sediment-transport competence in pools than in riffles at high flow. Pool-riffle sediment sorting may be created by velocity reversals, and more localized sorting results from gravitational forces along the upstream sloping portion of the channel bed located at the downstream end of pools.

Thompson, D.M.; Wohl, E.E.; Jarrett, R.D.

1996-01-01

329

Magnetism  

NSDL National Science Digital Library

This overview of magnetism provides a brief history prior to 1600 and continues with the work of William Gilbert, Hans Christian Oersted, and Andre-Marie Ampere in describing and exploring the magnetosphere and learning the role that electric current plays in producing magnetism. Magnetic field lines are then discussed, citing the work of Michael Faraday. The work of James Clerk Maxwell and Heinrich Hertz is mentioned in a discussion of the relationship of light waves and radio waves as part of the electromagnetic spectrum.

Stern, David

330

Molecular Expressions: Color Separation  

NSDL National Science Digital Library

This item is an interactive Java simulation for introductory physics students on the topic of color. It explores how individual subtractive primary colors can be separated from a full-color photograph and then be reassembled to create the original scene. The mouse cursor may be used to superimpose color separations over one another. As additional separations are added, the resulting image exhibits the realism of a color photograph. This item is part of a larger collection of materials on optics and microscopy developed by the National High Magnetic Field Laboratory and Florida State University.

Davidson, Michael; Parry-Hill, Matthew J.; Sutter, Robert

2008-08-21

331

Instrumentation status of the low-b magnet systems at the Large Hadron Collider (LHC)  

SciTech Connect

The low-{beta} magnet systems are located in the Large Hadron Collider (LHC) insertion regions around the four interaction points. They are the key elements in the beams focusing/defocusing process allowing proton collisions at luminosity up to 10{sup 34}cm{sup -2}s{sup -1}. Those systems are a contribution of the US-LHC Accelerator project. The systems are mainly composed of the quadrupole magnets (triplets), the separation dipoles and their respective electrical feed-boxes (DFBX). The low-{beta} magnet systems operate in an environment of extreme radiation, high gradient magnetic field and high heat load to the cryogenic system due to the beam dynamic effect. Due to the severe environment, the robustness of the diagnostics is primordial for the operation of the triplets. The hardware commissioning phase of the LHC was completed in February 2010. In the sake of a safer and more user-friendly operation, several consolidations and instrumentation modifications were implemented during this commissioning phase. This paper presents the instrumentation used to optimize the engineering process and operation of the final focusing/defocusing quadrupole magnets for the first years of operation.

Darve, C.; /Fermilab; Balle, C.; Casas-Cubillos, J.; Perin, A.; Vauthier, N.; /CERN

2011-05-01

332

On the use of magnetic nano and microparticles for lake restoration.  

PubMed

Innovative approaches are of outstanding importance to devise technologies for dealing with eutrophication of inland waters. This study provides a quantitative estimate showing the convenience of using magnetic nano- and micronsized particles as phosphate absorbents and their later removal from solution by high gradient magnetic separation. Two different materials are investigated (iron and magnetite) having a controlled shape and size well in the colloidal domain. Magnetite particles adsorb more phosphate (empirical saturation constant=27.15 mg P g(-1) Fe) than iron particles (empirical saturation constant=18.83 mg P g(-1) Fe) as a consequence of the different particle size (average values for particle diameters of 90.6+/-1.2 and 805+/-10 nm for magnetite and for iron, respectively). A protocol is established for the successful reutilization of these magnetic particles by repeated washing with NaOH and therefore, optimizing the economic cost of this technology. Magnetic particles are also surface treated with amino silane groups (APTS) to counteract magnetic and van der Waals attractive interactions and promote kinetic stability. APTS-coated iron particles experience a notable increase in phosphate maximum adsorption capacity which could be explained by a remarkable increase in electrophoretic mobility. We propose the use of APTS-coated iron particles which are less-expensive and easy to obtain as a promising technique for lake restoration. PMID:20554113

de Vicente, Inmaculada; Merino-Martos, Azahara; Cruz-Pizarro, Luis; de Vicente, Juan

2010-09-15

333

Separating Mixtures  

NSDL National Science Digital Library

Students learn how to classify materials as mixtures, elements or compounds and identify the properties of each type. The concept of separation of mixtures is also introduced since nearly every element or compound is found naturally in an impure state such as a mixture of two or more substances, and it is common that chemical engineers use separation techniques to separate mixtures into their individual components. For example, the separation of crude oil into purified hydrocarbons such as natural gas, gasoline, diesel, jet fuel and/or lubricants.

2014-09-18

334

GMAG PhD Dissertation Research Award Talk: Dynamic Magnetic Traps for Particle Self-Assembly and Lab-on-Chip Applications  

NASA Astrophysics Data System (ADS)

Micro-patterned Permalloy thin films serve as an excellent means to architect the spatial profile of magnetic fields with the tunable, high gradients required to manipulate objects with weak induced magnetic moments. In this presentation, I will highlight two projects carried out during my PhD studies. These findings demonstrate the functionalities achieved through carefully designed patterns of different sizes and shapes (e.g. circular, triangular, octagonal profiles): (i) By tuning a precessing magnetic field in conjunction with such Permalloy patterns, microsphere (i.e. dipole) cluster structures ranging from closely packed to frustrated and to plum-pudding-like planar lattices are stabilized. Such self-assembly of components at the micro to nanometer range not only support a rich variety of physical phenomena, but also have applications, for example, as filters or force probes and field-tunable photonic crystals. (ii) Mobile magnetic trap arrays consisting of Permalloy disks have enabled rapid transport of magnetic beads or immunomagnetically labeled cells across surfaces. Integration of these arrays with microfluidic droplet technology allows separation of labeled cells and their subsequent encapsulation into picoliter-sized droplets. The droplets serve as isolated containers for individual cells to be probed without cross-contamination. The separation-encapsulation function could become a critical component in point-of-care single-cell analysis platforms.

Chen, Aaron

2013-03-01

335

Field dependence of the electronic phase separation in Pr0.67Ca0.33MnO3 by small-angle magnetic neutron scattering  

NASA Astrophysics Data System (ADS)

We have studied, by small-angle magnetic neutron scattering, the evolution induced by the application of a magnetic field on the coexistence of ferromagnetism and antiferromagnetism in a crystal of Pr0.67Ca0.33MnO3. The results are compared to magnetic measurements, which provide the evolution of the ferromagnetic fraction. These results show that the growth of the ferromagnetic phase corresponds to an increase in the thickness of the ferromagnetic “cabbage” sheets.

Mercone, Silvana; Hardy, Vincent; Martin, Christine; Simon, Charles; Saurel, Damien; Brûlet, Annie

2003-09-01

336

Surface molecular imprinting onto fluorescein-coated magnetic nanoparticles via reversible addition fragmentation chain transfer polymerization: a facile three-in-one system for recognition and separation of endocrine disrupting chemicals.  

PubMed

In this study, we present a general protocol for the making of surface-imprinted magnetic fluorescence beads via reversible addition-fragmentation chain transfer polymerization. The resulting composites were characterized by X-ray diffraction analysis, transmission electron microscopy, scanning electron microscopy, fluorescence spectroscopy, Fourier transform infrared spectroscopy, and energy dispersive spectroscopy. The as-synthesized beads exhibited homogeneous polymer films (thickness of about 5.7 nm), spherical shape, high fluorescence intensity and magnetic property (Magnetization (Ms)=3.67 emu g(-1)). The hybrids bind the original template 17?-estradiol with an appreciable selectivity over structurally related compounds. In addition, the resulting hybrids performed without obvious deterioration after five repeated cycles. This study therefore demonstrates the potential of molecularly imprinted polymers for the recognition and separation of endocrine disrupting chemicals. PMID:21063623

Li, Ying; Dong, Cunku; Chu, Jia; Qi, Jingyao; Li, Xin

2011-01-01

337

Electrosteric stabilization and its role in cooperative magnetophoresis of colloidal magnetic nanoparticles.  

PubMed

A detailed study on the conflicting role that colloid stability plays in magnetophoresis is presented. Magnetic iron oxide particles (MIOPs) that were sterically stabilized via surface modification with poly(sodium 4-styrene sulfonate) of different molecular weights (i.e., 70 and 1000 kDa) were employed as our model system. Both sedimentation kinetics and quartz crystal microbalance with dissipation (QCM-D) measurements suggested that PSS 70 kDa is a better stabilizer as compared to PSS 1000 kDa. This observation is mostly attributed to the bridging flocculation of PSS 1000 kDa decorated MIOPs originated from the extended polymeric conformation layer. Later, a lab-scale high gradient magnetic separation (HGMS) device was designed to study the magnetophoretic collection of MIOPs. Our experimental results revealed that the more colloidally stable the MIOP suspension is, the harder it is to be magnetically isolated by HGMS. At 50 mg/L, naked MIOPs without coating can be easily captured by HGMS at separation efficiency up to 96.9 ± 2.6%. However, the degree of separation dropped quite drastically to 83.1 ± 1.2% and 67.7 ± 4.6%, for MIOPs with PSS 1000k and PSS 70k coating, respectively. This observation clearly implies that polyelectrolyte coating that was usually employed to electrosterically stabilize a colloidal system in turn compromises the magnetic isolation efficiency. By artificially destroying the colloidal stability of the MIOPs with ionic strength increment, the ability for HGMS to recover the most stable suspension (i.e., PSS 70k-coated MIOPs) increased to >86% at 100 mM monovalent ion (Na(+)) or at 10 mM divalent ion (Ca(2+)). This observation has verified the conflicting role of colloidal stability in magnetophoretic separation. PMID:23025323

Yeap, Swee Pin; Ahmad, Abdul Latif; Ooi, Boon Seng; Lim, Jitkang

2012-10-23

338

Stereoisomers Separation  

NASA Astrophysics Data System (ADS)

The use of capillary electrophoresis for enantiomer separation and optical purity determination is presented. The contents start with basic information about the nature of stereoizomers and the mechanism of enantioseparation using capillary electrophoresis techniques. The molecules to be separated show identical chemical structure and electrochemical behavior. Therefore, the chiral recognition of enantiomers is possible only by bonding to chiral selector and the separation based on very small differences in complexation energies of diastereomer complexes formed. This method is useful for this purpose due to the fact that different compounds can be used as chiral selectors. The mostly used chiral selectors like cyclodextrins, crown ethers, chiral surfactants, macrocyclic antibiotics, transition metal complexes, natural, and synthetic polymers and their application for this purpose is also discussed. Finally, examples of practical applications of electromigration techniques for enantiomers separation and determination are presented.

Wieczorek, Piotr

339

Fault Separation  

NSDL National Science Digital Library

Students use gestures to explore the relationship between fault slip direction and fault separation by varying the geometry of faulted layers, slip direction, and the perspective from which these are viewed.

Ormand, Carol

340

Map Separates  

USGS Publications Warehouse

U.S. Geological Survey (USGS) topographic maps are printed using up to six colors (black, blue, green, red, brown, and purple). To prepare your own maps or artwork based on maps, you can order separate black-and-white film positives or negatives for any color printed on a USGS topographic map, or for one or more of the groups of related features printed in the same color on the map (such as drainage and drainage names from the blue plate.) In this document, examples are shown with appropriate ink color to illustrate the various separates. When purchased, separates are black-and-white film negatives or positives. After you receive a film separate or composite from the USGS, you can crop, enlarge or reduce, and edit to add or remove details to suit your special needs. For example, you can adapt the separates for making regional and local planning maps or for doing many kinds of studies or promotions by using the features you select and then printing them in colors of your choice.

U.S. Geological Survey

2001-01-01

341

Isotope separation apparatus  

DOEpatents

Isotope separation apparatus consisting of a plurality of cells disposed adjacent to each other in an evacuated container. A common magnetic field is established extending through all of the cells. A source of energetic electrons at one end of the container generates electrons which pass through the cells along the magnetic field lines. Each cell includes an array of collector plates arranged in parallel or in tandem within a common magnetic field. Sets of collector plates are disposed adjacent to each other in each cell. Means are provided for differentially energizing ions of a desired isotope by applying energy at the cyclotron resonant frequency of the desired isotope. As a result, the energized desired ions are preferentially collected by the collector plates.

Arnush, Donald (Rancho Palos Verdes, CA); MacKenzie, Kenneth R. (Pacific Palisades, CA); Wuerker, Ralph F. (Palos Verdes Estates, CA)

1980-01-01

342

Chemical Separations  

NSDL National Science Digital Library

This site contains complete notes in a PowerPoint-like presentation for a chemical separations course. It covers a wide variety of topics, including distillation, extraction, gas chromatography, liquid chromatograpy, chromatography theory, instrumentation, electrophoresis, field flow fractionation, and affinity chromatography. It covers these topics thoroughly using a clear, consistent, and simple presentation style. Links to major topics like GC, LC, and electrophoresis provide specific information about the theory, instrumentation, and practice related to these techniques. The site also contains many annimations illustrating important separation processes.

343

Chromatographic Separations  

NSDL National Science Digital Library

This interactive applet provides a simulation of the separation of a mixture of 5 substances across a chromatographic column. The effect of changing various chromatographic factors can simultaneously be seen in the time-dependent dedistribution of analytes along the column along with the development of the chromatogram.

344

Phase-separation-induced changes in the magnetic and transport properties of the quaternary Heusler alloy Co2Mn1-xTixSn  

Microsoft Academic Search

The quaternary Heusler compound Co2Mn1-xTixSn with x=0 , 0.2, 0.4, 0.5, 0.6, 0.8, and 1 shows a phase separation into the two Heusler compounds, Co2MnSn and Co2TiSn . Only at the edges of the composition range a slight admixture of Mn and Ti to the respective other phase is observed. This phase separation leads to a distinct microstructure which can

Tanja Graf; Joachim Barth; Christian G. F. Blum; Benjamin Balke; Claudia Felser; Peter Klaer; Hans-Joachim Elmers

2010-01-01

345

Spontaneous formation of an exchange-spring composite via magnetic phase separation in Pr{sub 1-x}Ca{sub x}CoO{sub 3}.  

SciTech Connect

We present a neutron-diffraction, small-angle scattering, and magnetometry study of the narrow bandwidth perovskite cobaltite Pr{sub 1-x}Ca{sub x}CoO{sub 3}, demonstrating an unusual form of magnetoelectronic phase separation where long-range ordered ferromagnetism coexists spatially with short-range ferromagnetism. The two phases have very different coercivities and, remarkably, are strongly exchange coupled. The electronic phase separation thus leads to spontaneous formation of a hard-soft nanocomposite, exhibiting prototypical exchange-spring behavior in the absence of chemical interfaces.

El-Khatib, S.; Bose, S.; He, C.; Kuplic, J.; Laver, M.; Borchers, J. A.; Huang, Q.; Lynn, J. W.; Mitchell, J. F.; Leighton, C.; Materials Science Division; Univ. of Minnesota; NIST; Univ. of Maryland

2010-01-01

346

Battery separator  

SciTech Connect

In an alkaline dry cell battery separator being a laid mat of non-dissolvable polyvinyl alcohol fibers held together by a matrix of dissolved or partially dissolved dissolvable polyvinyl alcohol fibers, an improvement is described comprising the mat having up to 85% of cellulosic fibers relatively uniformly distributed in and among the non-dissolvable polyvinyl alcohol fibers and held therein by the matrix.

La Bonte, R.J.

1988-08-30

347

Magnetic Materials  

NSDL National Science Digital Library

Students begin working on the grand challenge of the unit by thinking about the nature of metals and quick, cost-effective means of separating different metals, especially steel. They arrive at the idea, with the help of input from relevant sources, to use magnets, but first they must determine if the magnets can indeed isolate only the steel.

Vu Bioengineering Ret Program

348

High Gradient Acceleration in a 17 GHz Photocathode RF Gun* S. C. Chen, J. Gonichon, 1;. C-L. Lin, R. J. Temkin, S. Trotz, B. G. Danly, and J. S. Wurtele  

E-print Network

High Gradient Acceleration in a 17 GHz Photocathode RF Gun* S. C. Chen, J. Gonichon, 1;. C-L. Lin.icle acceleration at high mi- ccowave (RF) frequencies are under study at hIIT. The 17 GHz photocathode RF gun has, efforts have been made recent,ly t,o creat,e novel electron beam sources.[l] While existing RF guns

Wurtele, Jonathan

349

Phase separation in thermoelectric delafossite CuFe1-xNixO2 observed by soft x-ray magnetic circular dichroism  

NASA Astrophysics Data System (ADS)

Electronic structures of Ni-doped CuFe1-xNixO2 delafossite oxides (0 ? x ? 0.03) have been investigated by employing soft x-ray magnetic circular dichroism (XMCD). Finite XMCD signals are observed for Fe, Ni, and Cu 2p states, and valence states of Cu, Fe, and Ni ions are nearly monovalent (Cu+), trivalent (Fe3+), and divalent (Ni2+), respectively, for all x ? 0.03. Tiny magnetic impurities could be detected by employing XMCD. Fe and Ni 2p XMCD signals are identified due to ferrimagnetic spinel impurities of CuFe2O4 and NiFe2O4. XMCD signals for Cu 2p states arise from divalent Cu2+ ions. Thermoelectrical properties are found to be very sensitive to the very little impurity phase present in delafossite oxides.

Kang, J.-S.; Kim, D. H.; Hwang, Jihoon; Lee, Eunsook; Nozaki, T.; Hayashi, K.; Kajitani, T.; Park, B.-G.; Kim, J.-Y.; Min, B. I.

2011-07-01

350

Application of magnetic solid phase extraction for separation and determination of aflatoxins B ? and B? in cereal products by high performance liquid chromatography-fluorescence detection.  

PubMed

A simple and sensitive method based on the magnetic solid phase extraction with modified magnetic nanoparticles followed by high performance liquid chromatography with fluorescence detection has been developed for extraction and determination of aflatoxins B1 (AFB1) and B2 (AFB2) in cereal products. Magnetic nanoparticle coated with 3-(trimethoxysilyl)-1-propanthiol (TMSPT) and modified with 2-amino-5-mercapto-1,3,4-thiadiazole (AMT) was used as an antibody-free adsorbent. Under the optimal conditions, the calibration curves for AFB1 and AFB2 were linear in the ranges of 0.2-15 ?g L(-1) and 0.04-3 ?g L(-1), respectively. Detection limit was 0.041 ?g L(-1) for AFB1 and 0.013 ?g L(-1) for AFB2. The proposed method was successfully applied to the determination of AFB1 and AFB2 in spiked corn and rice samples with an average recovery of 93.5%. The results demonstrated that the developed method is simple, rapid, inexpensive, accurate and remarkably free from interference effects. PMID:24814005

Hashemi, Mahdi; Taherimaslak, Zohreh; Rashidi, Somayeh

2014-06-01

351

Gas separating  

DOEpatents

Feed gas is directed tangentially along the non-skin surface of gas separation membrane modules comprising a cylindrical bundle of parallel contiguous hollow fibers supported to allow feed gas to flow from an inlet at one end of a cylindrical housing through the bores of the bundled fibers to an outlet at the other end while a component of the feed gas permeates through the fibers, each having the skin side on the outside, through a permeate outlet in the cylindrical casing. 3 figs.

Gollan, A.

1988-03-29

352

Gas separating  

DOEpatents

Feed gas is directed tangentially along the non-skin surface of gas separation membrane modules comprising a cylindrical bundle of parallel contiguous hollow fibers supported to allow feed gas to flow from an inlet at one end of a cylindrical housing through the bores of the bundled fibers to an outlet at the other end while a component of the feed gas permeates through the fibers, each having the skin side on the outside, through a permeate outlet in the cylindrical casing. 3 figs.

Gollan, A.Z.

1990-12-25

353

Design and characterization of Ni2+ and Co2+ decorated Porous Magnetic Silica spheres synthesized by hydrothermal-assisted modified-Stöber method for His-tagged proteins separation.  

PubMed

The complete elimination of enzymes from the reaction mixture and the possibility of its recycling for several rounds result in great benefits, allowing the reduction of the enzyme consumption and their usability in continuous processes. In this work, it is evaluated the capture of a H6-tagged green fluorescence protein (GFP-H6) on porous magnetic spheres using the Co(2+) and Ni(2+) affinity adsorption as a possible cost-effective and up-scaled alternative way for the immobilization of His-tagged proteins. For this purpose, Porous Magnetic Silica (PMS) spheres were synthesized by one-step hydrothermal-assisted modified-Stöber method. The obtained spheres have a homogenous size distribution of 400 nm diameter. The ?-Fe(2)O(3) nanoparticles are homogenously distributed in the silica matrix. The obtained PMS spheres have a saturation magnetization of about 10 emu/g. Magnetophoresis measurements show a total separation time of 16 min at 60 T/m. The obtained PMS spheres were successfully and homogenously decorated with Co(2+) and Ni(2+) and then evaluated for the capture of a GFP-H6 protein. The results were compared with the performance of the commercial beads Dynabeads® His-Tag Isolation & Pulldown. PMID:21996010

Benelmekki, M; Xuriguera, E; Caparros, C; Rodríguez-Carmona, E; Mendoza, R; Corchero, J L; Lanceros-Mendez, S; Martinez, Ll M

2012-01-01

354

Particle separation  

NASA Technical Reports Server (NTRS)

Embodiments of a method for selecting particles, such as based on their morphology, is disclosed. In a particular example, the particles are charged and acquire different amounts of charge, or have different charge distributions, based on their morphology. The particles are then sorted based on their flow properties. In a specific example, the particles are sorted using a differential mobility analyzer, which sorts particles, at least in part, based on their electrical mobility. Given a population of particles with similar electrical mobilities, the disclosed process can be used to sort particles based on the net charge carried by the particle, and thus, given the relationship between charge and morphology, separate the particles based on their morphology.

Moosmuller, Hans (Inventor); Chakrabarty, Rajan K. (Inventor); Arnott, W. Patrick (Inventor)

2011-01-01

355

Separation of vinca alkaloid enantiomers by capillary electrophoresis applying cyclodextrin derivatives and characterization of cyclodextrin complexes by nuclear magnetic resonance spectroscopy.  

PubMed

In this work, the enantiomeric separation of three vinca alkaloid enantiomers (vincamine, vinpocetine and vincadifformine) has been investigated in an aqueous capillary electrophoresis (CE) system using cyclodextrins (CDs). The investigated CDs were the native alpha-, beta-, and gamma-CDs and their hydroxypropylated, randomly methylated, carboxymethylated and sulfobutylated derivatives. The first part of this study consisted of the determination of the apparent averaged complex stability constants with the selected CDs. Several parameters, such as the nature and the concentration of the CD, were studied and were found to have a significant effect on the enantiomeric resolution for all studied compounds. All three vinca alkaloids were successfully enantioseparated with CDs where different migration orders were observed in case of several CDs depending on the cavity size or substituent of the host. Chiral separation and determination of the stability constants were also performed with NMR spectroscopy which confirmed the CE results. Averaged stoichiometries of the complexes were determined using the Job plot method resulting in a 1:1 complex irrespective of the alkaloid enantiomers or cyclodextrin derivative. The structures of the inclusion complexes were elucidated using 2D ROESY NMR spectroscopy. On the basis of NMR results reversal of enantiomer migration order was clarified in various cases. PMID:20724093

Sohajda, Tamás; Varga, Erzsébet; Iványi, Róbert; Fejos, Ida; Szente, Lajos; Noszál, Béla; Béni, Szabolcs

2010-12-15

356

Coupling Immunomagnetic Separation on Magnetic Beads with Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry for Detection of Staphylococcal Enterotoxin B?  

PubMed Central

The growing importance of mass spectrometry for the identification and characterization of bacterial protein toxins is a consequence of the improved sensitivity and specificity of mass spectrometry-based techniques, especially when these techniques are combined with affinity methods. Here we describe a novel method based on the use of immunoaffinity capture and matrix-assisted laser desorption ionization-time of flight mass spectrometry for selective purification and detection of staphylococcal enterotoxin B (SEB). SEB is a potent bacterial protein toxin responsible for food poisoning, as well as a potential biological warfare agent. Unambiguous detection of SEB at low-nanogram levels in complex matrices is thus an important objective. In this work, an affinity molecular probe was prepared by immobilizing anti-SEB antibody on the surface of para-toluene-sulfonyl-functionalized monodisperse magnetic particles and used to selectively isolate SEB. Immobilization and affinity capture procedures were optimized to maximize the density of anti-SEB immunoglobulin G and the amount of captured SEB, respectively, on the surface of magnetic beads. SEB could be detected directly “on beads” by placing the molecular probe on the matrix-assisted laser desorption ionization target plate or, alternatively, “off beads” after its acidic elution. Application of this method to complex biological matrices was demonstrated by selective detection of SEB present in different matrices, such as cultivation media of Staphylococcus aureus strains and raw milk samples. PMID:17827336

Schlosser, Gitta; Ka?er, Petr; Kuzma, Marek; Szilágyi, Zoltán; Sorrentino, Alida; Manzo, Carla; Pizzano, Rosa; Malorni, Livia; Pocsfalvi, Gabriella

2007-01-01

357

Magnetically separable {gamma}-Fe{sub 2}O{sub 3}-SiO{sub 2}-Ce-doped TiO{sub 2} core-shell nanocomposites: Fabrication and visible-light-driven photocatalytic activity  

SciTech Connect

Novel visible-light-induced {gamma}-Fe{sub 2}O{sub 3}-SiO{sub 2}-Ce-doped-TiO{sub 2} core-shell nanocomposite photocatalysts capable of magnetic separation have been synthesized by a facile sol-gel and after-annealing process. The as-obtained core-shell nanocomposite is composed of a central {gamma}-Fe{sub 2}O{sub 3} core with a strong response to external fields, an interlayer of SiO{sub 2}, and an outer layer of Ce-doped TiO{sub 2} nanocrystals. UV-vis spectra analysis indicates that Ce doping in the compound results in a red-shift of the absorption edge, thus offering increased visible light absorption. We show that such a {gamma}-Fe{sub 2}O{sub 3}-SiO{sub 2}-Ce-doped-TiO{sub 2} core-shell nanocomposite with appreciated Ce doping amount exhibits much higher visible-light photocatalytic activity than bare TiO{sub 2} and undoped {gamma}-Fe{sub 2}O{sub 3}-SiO{sub 2}-TiO{sub 2} core-shell nanocomposite toward the degradation of rhodamine B (RhB). Moreover, the {gamma}-Fe{sub 2}O{sub 3}-SiO{sub 2}-Ce-doped-TiO{sub 2} core-shell nanocomposite photocatalysts could be easily separated and reused from the treated water under application of an external magnetic field. - Graphical abstract: Novel {gamma}-Fe{sub 2}O{sub 3}-SiO{sub 2}-Ce-doped-TiO{sub 2} core/shell nanocomposite photocatalysts with enhanced photocatalytic activity and fast magnetic separability were prepared. Highlights: Black-Right-Pointing-Pointer Novel {gamma}-Fe{sub 2}O{sub 3}-SiO{sub 2}-Ce-doped TiO{sub 2} core/shell composite photocatalysts were prepared. Black-Right-Pointing-Pointer The resulting core/shell composite show high visible light photocatalytic activity. Black-Right-Pointing-Pointer The nanocomposite photocatalysts can be easily recycled with excellent durability.

He, Minqiang, E-mail: jbmwgkc@126.com [School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang 212013 (China); Li, Di; Jiang, Deli; Chen, Min [School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang 212013 (China)

2012-08-15

358

Oil separator  

SciTech Connect

This patent describes an oil separator for a horizontal screw compressor: a generally cylindrical member having a closed first end and having a second end having an opening therein for receiving the rotor assembly of a screw compressor; baffle seal means spaced from the closed first end and defining therewith a first chamber; generally horizontal divider plate means extending between the baffle seal means and the second end so as to divide the generally cylindrical member to thereby define second and third chambers with the second chamber being beneath and larger than the third chamber; the opening in the second end communicates with the second chamber whereby the second chamber is adapted to receive the rotor assembly; discharge deflector means in the second chamber for directing compressor discharge upwardly so as to impinge upon the divider plate means and deposit entrained oil thereon; demister means in the second chamber and coacting with the baffle seal means whereby compressor discharge must pass through the demister means to reach the first chamber.

Calupca, G.A.; Crone, L.L.; Maxey, W. III; Rubenic, E.K.

1988-12-06

359

Magnetophoretic label-free cell separation using paramagnetic solution  

Microsoft Academic Search

In this paper, we present a new magnetophoretic cell separation method based on the magnetic susceptibility differences between cells and medium. Since the dimension of cells is only a few dozen micrometers, it is difficult to discriminate cells only by low magnetic force acting on biological cells. To improve the efficiency of this label-free magnetophoretic separation, the magnetic susceptibility of

F. Shen; H. Hwang; Y. K. Hahn; J.-K. Park

2011-01-01

360

Separation profile of model water-in-oil emulsions followed by nuclear magnetic resonance (NMR) measurements: application range and comparison with a multiple-light scattering based apparatus.  

PubMed

The application range and validity of two new NMR sequences (hereafter called sequence 1 and sequence 2) for the study of water-in-oil emulsions (w/o) has been assessed using model emulsions and comparison with results obtained by a commercial apparatus (Turbiscan). These new NMR sequences allow to determine the brine profile i.e. the vertical variations of the dispersed phase content (brine) in the NMR tube. Measuring these parameters as a function of time allows to monitor the separation (sedimentation and coalescence rate) between oil and water. The results obtained on model water-in-oil emulsions with both NMR sequences are consistent and meaningful for both stable and coalescing emulsions and are similar, even if not strictly identical, to the ones obtained with the Turbiscan. It also appears that the second NMR sequence is faster (30s to obtain a profile compared with 3 min for the 1st one in the conditions used in this article) and has a broader application range. Indeed, for these two methods, the oil phase must have a viscosity higher or equal than values which is around 5 mPas for the sequence 2 and 20-25 mPas for the method 1. PMID:21288535

Simon, Sébastien; Pierrard, Xavier; Sjöblom, Johan; Sørland, Geir H

2011-04-01

361

Coupling of magnetic field and lattice strain and its impact on electronic phase separation in La{sub 0.335}Pr{sub 0.335}Ca{sub 0.33}MnO{sub 3}/ferroelectric crystal heterostructures  

SciTech Connect

Phase-separated La{sub 0.335}Pr{sub 0.335}Ca{sub 0.33}MnO{sub 3} films were epitaxially grown on (001)- and (111)-oriented ferroelectric single-crystal substrates. Upon poling along the [001] or [111] direction, dramatic decrease in resistance, up to 99.98%, and complete melting of the charge-ordered phase were observed, caused by poling-induced strain rather than accumulation of electrostatic charge at interface. Such poling-induced strain effects can be effectively tuned by a magnetic field and mediated by electronic phase separation. In particular, our findings show that the evolution of the strength of electronic phase separation against temperature and magnetic field can be determined by measuring the strain-tunability of resistance [(?R/R){sub strain}] under magnetic fields.

Zheng, M.; Yang, M. M.; Zhu, Q. X.; Li, X. M.; Shi, X.; Luo, H. S.; Zheng, R. K., E-mail: zrk@ustc.edu [State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050 (China); Li, X. Y. [State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050 (China) [State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050 (China); Department of Materials Science and Engineering, Nanjing University of Science and Technology, Nanjing 210094 (China); Wang, Y.; Chan, H. L. W. [Department of Applied Physics and Materials Research Center, The Hong Kong Polytechnic University, Hong Kong (China)] [Department of Applied Physics and Materials Research Center, The Hong Kong Polytechnic University, Hong Kong (China); Li, X. G. [Hefei National Laboratory for Physical Sciences at Microscale and Department of Physics, University of Science and Technology of China, Hefei 230026 (China)] [Hefei National Laboratory for Physical Sciences at Microscale and Department of Physics, University of Science and Technology of China, Hefei 230026 (China)

2013-12-23

362

Separation of Gd-humic complexes and Gd-based magnetic resonance imaging contrast agent in river water with QAE-Sephadex A-25 for the fractionation analysis.  

PubMed

Gadolinium complexed with naturally occurring, negatively charged humic substances (humic and fulvic acids) was collected from 500 mL of sample solution onto a column packed with 150 mg of a strongly basic anion-exchanger (QAE-Sephadex A-25). A Gd-based magnetic resonance imaging contrast agent (diethylenetriamine-N,N,N',N?,N?-pentaacetato aquo gadolinium(III), Gd-DTPA(2-)) was simultaneously collected on the same column. The Gd-DTPA complex was desorbed by anion-exchange with 50mM tetramethylammonium sulfate, leaving the Gd-humic complexes on the column. The Gd-humic complexes were subsequently dissociated with 1M nitric acid to desorb the humic fraction of Gd. The two-step desorption with small volumes of the eluting agents allowed the 100-fold preconcentration for the fractionation analysis of Gd at low ng L(-1) levels by inductively coupled plasma-mass spectrometry (ICP-MS). On the other hand, Gd(III) neither complexed with humic substances nor DTPA, i.e., free species, was not sorbed on the column. The free Gd in the effluent was preconcentrated 100-fold by a conventional solid-phase extraction with an iminodiacetic acid-type chelating resin and determined by ICP-MS. The proposed analytical fractionation method was applied to river water samples. PMID:25059192

Matsumiya, Hiroaki; Inoue, Hiroto; Hiraide, Masataka

2014-10-01

363

Synthesis of magnetically separable Ag3PO4/TiO2/Fe3O4 heterostructure with enhanced photocatalytic performance under visible light for photoinactivation of bacteria.  

PubMed

Silver orthophosphate (Ag3PO4) is a low-band-gap photocatalyst that has received considerable research interest in recent years. In this work, the magnetic Ag3PO4/TiO2/Fe3O4 heterostructured nanocomposite was synthesized. The nanocomposite was found to exhibit markedly enhanced photocatalytic activity, cycling stability, and long-term durability in the photodegradation of acid orange 7 (AO7) under visible light. Moreover, the antibacterial film prepared from Ag3PO4/TiO2/Fe3O4 nanocomposite presented excellent bactericidal activity and recyclability toward Escherichia coli (E. coli) cells under visible-light irradiation. In addition to the intrinsic cytotoxicity of silver ions, the elevated bactericidal efficiency of Ag3PO4/TiO2/Fe3O4 can be largely attributed to its highly enhanced photocatalytic activity. The photogenerated hydroxyl radicals and superoxide ions on the formed Ag/Ag3PO4/TiO2 interfaces cause considerable morphological changes in the microorganism's cells and lead to the death of the bacteria. PMID:25140916

Xu, Jing-Wen; Gao, Zhi-Da; Han, Kun; Liu, Yongmin; Song, Yan-Yan

2014-09-10

364

Are There Separate Neural Systems for Spelling? New Insights into the Role of Rules and Memory in Spelling from Functional Magnetic Resonance Imaging.  

PubMed

How do people spell the thousands of words at the tips of their tongues? Are words with regular sound-to-letter correspondences (e.g., "blink") spelled using the same neural systems as those with irregular correspondences (e.g., "yacht")? By offering novel neuroimaging evidence, we aim to advance contemporary debate about whether people use a single lexical memory process or whether dual mechanisms of lexical memory and sublexical phonological rules work in concert. We further aim to advance understanding of how people read by taking a fresh look at the related yet distinct capacity to spell. During functional magnetic resonance imaging scanning, 12 participants heard low-frequency regular words, irregular words, and nonwords (e.g., "shelm") and responded whether a visual presentation of the word was spelled correctly or incorrectly. While behavioral measures suggested some differences in accuracy and reaction time for the different word types, the neuroimaging results alone demonstrated robust differential processing and support a dual-route model of spelling, with implications for how spelling is taught and remediated in clinical and educational contexts. PMID:20011680

Norton, Elizabeth S; Kovelman, Ioulia; Petitto, Laura-Ann

2007-03-01

365

Rapid magnetophoretic separation of microalgae.  

PubMed

Magnetic collection of the microalgae Chlorella sp. from culture media facilitated by low-gradient magnetophoretic separation is achieved in real time. A removal efficiency as high as 99% is accomplished by binding of iron oxide nanoparticles (NPs) to microalgal cells in the presence of the cationic polyelectrolyte poly(diallyldimethylammonium chloride) (PDDA) as a binder and subsequently subjecting the mixture to a NdFeB permanent magnet with surface magnetic field ?6000 G and magnetic field gradient <80 T m(-1) . Surface functionalization of magnetic NPs with PDDA before exposure to Chlorella sp. is proven to be more effective in promoting higher magnetophoretic removal efficiency than the conventional procedure, in which premixing of microalgal cells with binder is carried out before the addition of NPs. Rodlike NPs are a superior candidate for enhancing the magnetophoretic separation compared to spherical NPs due to their stable magnetic moment that originates from shape anisotropy and the tendency to form large NP aggregates. Cell chaining is observed for nanorod-tagged Chlorella sp. which eventually fosters the formation of elongated cell clusters. PMID:22438107

Lim, Jit Kang; Chieh, Derek Chan Juinn; Jalak, Selah A; Toh, Pey Yi; Yasin, Nur Hidayah Mat; Ng, Bee Wah; Ahmad, Abdul Latif

2012-06-11

366

Experimental and theoretical studies of implant assisted magnetic drug targeting  

NASA Astrophysics Data System (ADS)

One way to achieve drug targeting in the body is to incorporate magnetic nanoparticles into drug carriers and then retain them at the site using an externally applied magnetic field. This process is referred to as magnetic drug targeting (MDT). However, the main limitation of MDT is that an externally applied magnetic field alone may not be able to retain a sufficient number of magnetic drug carrier particles (MDCPs) to justify its use. Such a limitation might not exist when high gradient magnetic separation (HGMS) principles are applied to assist MDT by means of ferromagnetic implants. It was hypothesized that an Implant Assisted -- MDT (IA-MDT) system would increase the retention of the MDCPs at a target site where an implant had been previously located, since the magnetic forces are produced internally. With this in mind, the overall objective of this work was to demonstrate the feasibility of an IA-MDT system through mathematical modeling and in vitro experimentation. The mathematical models were developed and used to demonstrate the behavior and limitations of IA-MDT, and the in vitro experiments were designed and used to validate the models and to further elucidate the important parameters that affect the performance of the system. IA-MDT was studied with three plausible implants, ferromagnetic stents, seed particles, and wires. All implants were studied theoretically and experimentally using flow through systems with polymer particles containing magnetite nanoparticles as MDCPs. In the stent studies, a wire coil or mesh was simply placed in a flow field and the capture of the MDCPs was studied. In the other cases, a porous polymer matrix was used as a surrogate capillary tissue scaffold to study the capture of the MDCPs using wires or particle seeds as the implant, with the seeds either fixed within the polymer matrix or captured prior to capturing the MDCPs. An in vitro heart tissue perfusion model was also used to study the use of stents. In general, all the results demonstrated that IA-MDT is indeed feasible and that careful modification of the MDCP properties and implant properties are fundamental to the success of this technology.

Aviles, Misael O.

367

College of Engineering Electromagnetically Enhanced Hydrocyclone for Magnetite Separation during  

E-print Network

PENNSTATE College of Engineering Electromagnetically Enhanced Hydrocyclone for Magnetite Separation, but pose a safety risk due to the constant magnetic field. The Spring 2011 team des electromagnetic Electromagnetically Enhanced Hydrocyclone for Magnetite Separation during Coal Beneficiation Magnetite is used

Demirel, Melik C.

368

The Superconducting Interaction Region Magnet System for the CESRhttp:\\/\\/www.lns.cornell.edu Phase III Upgrade  

Microsoft Academic Search

Deep inside the CLEO III detector will be two pairs of new high gradient superconducting interaction region magnets. Their close proximity to the interaction point, short focal lengths and large warm bore diameter are all optimized for the highest possible luminosity using crossing angles and bunch trains. Superposed with the main quadrupole fields are fields from skew quadrupole coils for

James J. Welch; Gerald F. Dugan; Nordberg Emery; David Rice

1997-01-01

369

Drawing Magnetic Fields  

NSDL National Science Digital Library

Students use a compass and a permanent magnet to trace the magnetic field lines produced by the magnet. By positioning the compass in enough spots around the magnet, the overall magnet field will be evident from the collection of arrows representing the direction of the compass needle. In activities 3 and 4 of this unit, students will use this information to design a way to solve the grand challenge of separating metal for a recycling company.

2014-09-18

370

Electricity and Magnetic Fields  

NSDL National Science Digital Library

The grand challenge for this legacy cycle unit is for students to design a way to help a recycler separate aluminum from steel scrap metal. In previous lessons, they have looked at how magnetism might be utilized. In this lesson, students think about how they might use magnets and how they might confront the problem of turning the magnetic field off. Through the accompanying activity students explore the nature of an electrically induced magnetic field and its applicability to the needed magnet.

VU Bioengineering RET Program,

371

Activated Carbon Composites for Air Separation  

SciTech Connect

In continuation of the development of composite materials for air separation based on molecular sieving properties and magnetic fields effects, several molecular sieve materials were tested in a flow system, and the effects of temperature, flow conditions, and magnetic fields were investigated. New carbon materials adsorbents, with and without pre-loaded super-paramagnetic nanoparticles of Fe3O4 were synthesized; all materials were packed in chromatographic type columns which were placed between the poles of a high intensity, water-cooled, magnet (1.5 Tesla). In order to verify the existence of magnetodesorption effect, separation tests were conducted by injecting controlled volumes of air in a flow of inert gas, while the magnetic field was switched on and off. Gas composition downstream the column was analyzed by gas chromatography and by mass spectrometry. Under the conditions employed, the tests confirmed that N2 - O2 separation occurred at various degrees, depending on material's intrinsic properties, temperature and flow rate. The effect of magnetic fields, reported previously for static conditions, was not confirmed in the flow system. The best separation was obtained for zeolite 13X at sub-ambient temperatures. Future directions for the project include evaluation of a combined system, comprising carbon and zeolite molecular sieves, and testing the effect of stronger magnetic fields produced by cryogenic magnets.

Contescu, Cristian I [ORNL; Baker, Frederick S [ORNL; Tsouris, Costas [ORNL; McFarlane, Joanna [ORNL

2008-03-01

372

Magnetic nanotubes  

DOEpatents

A magnetic nanotube includes bacterial magnetic nanocrystals contacted onto a nanotube which absorbs the nanocrystals. The nanocrystals are contacted on at least one surface of the nanotube. A method of fabricating a magnetic nanotube includes synthesizing the bacterial magnetic nanocrystals, which have an outer layer of proteins. A nanotube provided is capable of absorbing the nanocrystals and contacting the nanotube with the nanocrystals. The nanotube is preferably a peptide bolaamphiphile. A nanotube solution and a nanocrystal solution including a buffer and a concentration of nanocrystals are mixed. The concentration of nanocrystals is optimized, resulting in a nanocrystal to nanotube ratio for which bacterial magnetic nanocrystals are immobilized on at least one surface of the nanotubes. The ratio controls whether the nanocrystals bind only to the interior or to the exterior surfaces of the nanotubes. Uses include cell manipulation and separation, biological assay, enzyme recovery, and biosensors.

Matsui, Hiroshi (Glen Rock, NJ); Matsunaga, Tadashi (Tokyo, JP)

2010-11-16

373

Preparation and characterization of monodisperse core-shell Fe3O4@SiO2 microspheres and its application for magnetic separation of nucleic acids from E. coli BL21.  

PubMed

In this article, we present an easy route to prepare monodisperse core-shell Fe3O4@SiO2 microspheres with uniform size and shape. Their structures and properties were studied by transmission electron microscopy (TEM), scanning electron microscopy (SEM), Fourier transform infrared spectrometry (FT-IR), and vibrating sample magnetometer (VSM), respectively. The results showed that spherical Fe3O4 microspheres with well dispersion have a rough surface and an average diameter (about 500 nm). After the modification with silica, the particles have a well-defined core-shell structure and a much smoother surface and larger particle diameter (about 600 nm). Furthermore, VSM measurements indicated that the as-prepared Fe3O4 and Fe3O4@SiO2 microspheres were superparamagnetic at room temperature and the saturation magnetization (M(s)) were 58.110 emu/g and 33.479 emu/g, respectively. And then, the prepared monodisperse core-shell Fe3O4@SiO2 microspheres were subsequently applied to separate nucleic acids from the bacteria (E. coli BL21) and verified the great application prospects for bioseparation technology of the biomoleculars. PMID:23030008

Ma, Chao; Li, Chuanyan; He, Nongyue; Wang, Fang; Ma, Ningning; Zhang, Liming; Lu, Zhuoxuan; Ali, Zeeshan; Xi, Zhijiang; Li, Xiaolong; Liang, Gaofeng; Liu, Hongna; Deng, Yan; Xu, Lijian; Wang, Zhifei

2012-12-01

374

The influence of palaeotopography on facies architecture and pyroclastic flow processes of a lithic-rich ignimbrite in a high gradient setting: The Abrigo Ignimbrite, Tenerife, Canary Islands  

NASA Astrophysics Data System (ADS)

The late Pleistocene (188 ± 19 ka) Abrigo Ignimbrite represents the last major explosive caldera-forming eruption on Tenerife. It consists almost entirely of a moderate volume (? 1.8 km 3) light grey phonolitic lithic-rich ignimbrite deposit, although a possible Abrigo Member thin fall deposit is locally preserved beneath the ignimbrite, suggesting an initial short-lived stable plinian eruption column. The ignimbrite deposit is dispersed radially around the lower flanks of the Las Cañadas edifice and correlates to a clast-supported lithic breccia on the eastern and northern caldera wall. Much of the ignimbrite was probably deposited offshore or within the caldera, now buried by more recent lavas. Two major depositional units, separated by a co-ignimbrite ash cloud deposit, and which display dramatic variations in thickness (< 1 to 25 m thick) and facies architecture across the radial drainage pattern, occur across most of the southern coastal plain of the island. Valley-ponded, massive, lithic-rich ignimbrite deposits were deposited by progressive aggradation from a sustained pyroclastic flow. Matrix-supported lithic block concentration zones within depositional units consist of either entrained, locally derived or vent-derived lithic clasts and were deposited in valleys during intervals of relatively high flow energy. Stratified ignimbrite veneer deposits on palaeoridges were deposited by incremental aggradation under pulsatory flow conditions. Valley-ponded to veneer deposit transitions, which occur over even subtle variations in topographic relief, were controlled by the bulk flow velocity, lithic-rich nature (high bulk density) and moderate volume of the pyroclastic flow system. Pumice-rich ignimbrite facies (matrix-supported pumice concentration zones; massive, pumice-rich ignimbrite lobes; planar and laterally complex stratified pumice-rich ignimbrite) were distributed at the deposit front or where the upper pumiceous part of the pyroclastic flow interacted with palaeoridges. Localised facies and bedforms were associated with complex topographic features. Multiple depositional units of massive, lithic-rich ignimbrite occur on the northern and western flanks of the Las Cañadas edifice. The steeper, more vegetated northern flanks also enhanced fines-depletion in the formation of clast-supported lithic breccia. Pyroclastic flows were channelised along and deposited within the same valleys that exist today and were commonly continuous and sheet-like across the interfluves. The basal zones of pyroclastic flows are envisaged as a bed-load of coarse lithic lapilli and blocks transported under their own momentum and with the support of the surrounding fine ash-gas granular flow.

Pittari, A.; Cas, R. A. F.; Edgar, C. J.; Nichols, H. J.; Wolff, J. A.; Martí, J.

2006-04-01

375

Spacecraft -- Capsule Separation (Animation)  

NASA Technical Reports Server (NTRS)

[figure removed for brevity, see original site] Click on the image for Spacecraft -- Capsule Separation animation

This animation shows the return capsule separating from the Stardust spacecraft.

2005-01-01

376

A Conduction Cooled High Temperature Superconductor Quadrupolar Superferric Magnet, Design and Construction  

NASA Astrophysics Data System (ADS)

The paper presents the prototype of an YBCO superferric quadrupolar magnet for high gradient magnetic field generation, design and construction. The temperature of the superconducting coil has to be kept within safe limits or the HTS would exit the superconductive state. Of particular concern is the "warm" beam tube that passes through the magnet. Cryogenic conduction cooling with a closed cycle G-M Cooler may ensure the removal of the ambient heat influx. Numerical simulation results on the magnetic field and heat transfer problems are then discussed. The computational domain is abstracted out of the CAD design of the system. The design solution is presented and compared with the numerical simulations results.

Dobrin, I.; Morega, A. M.; Nedelcu, A.; Morega, M.; Neamtu, J.

2014-05-01

377

Permanent Magnet Machines: Asychronous Operation  

Microsoft Academic Search

The permanent magnet motor operating at subsynchronous speeds, as during run-up, is treated with particular emphasis placed on the role that magnet excitation plays. The torque, during run-up, is separated into components called the \\

V. B. Honsinger

1980-01-01

378

New magnetic nanoparticles for biotechnology  

Microsoft Academic Search

Paramagnetic carriers, which are linked to antibodies enable highly specific biological cell separations. With the colloidal synthesis of superparamagnetic Co and FeCo nanocrystals with superior magnetic moments the question about their potential to replace magnetite as the magnetically responsive component of magnetic beads is addressed. Starting from a magnetic analysis of the corresponding magnetophoretic mobility of Co and FeCo based

Andreas Hütten; Daniela Sudfeld; Inga Ennen; Günter Reiss; Wiebke Hachmann; Ulrich Heinzmann; Klaus Wojczykowski; Peter Jutzi; Wahib Saikaly; Gareth Thomas

2004-01-01

379

Vacuum arc plasma mass separator  

NASA Astrophysics Data System (ADS)

The propagation of a metal plasma flow in a transport system with a curvilinear magnetic field was studied experimentally. The flow was generated by a pulsed vacuum arc discharge with a composite (W+Fe) cathode. The ion energy measurements at the transport system output showed that all ion components were accelerated up to equal energies per charge unit, about 150 eV and 320 eV in the outer and inner areas of the curved plasma flow, respectively. The spatial separation of the atoms of the cathode material was measured at the system output by x-ray fluorescence spectrometry. The ions of the lighter element (Fe) were concentrated in the inner part of the cathodic plasma flow deflected by the magnetic field while the distribution of the heavy element (W) was substantially shifted toward the outer area of the flow. The maximum mass separation efficiency reached 45, the effective value being 7.7. Such a system is promising for use in plasma technology for reprocessing spent nuclear fuel, namely for the separation of the heavy radioactive fission product from nuclear waste.

Paperny, V. L.; Krasov, V. I.; Lebedev, N. V.; Astrakchantsev, N. V.; Chernikch, A. A.

2015-02-01

380

Thermodynamic and transport properties of non-magnetic particles in magnetic fluids  

E-print Network

Magnetic composites, obtained on associating magnetic fluid with non-magnetic particles, offer interesting opportunities in separations, assemblies and other applications, where the microstructure of the composite can be ...

Tejwani, Saurabh

2009-01-01

381

The nature of separator current layers in MHS equilibria. I. Current parallel to the separator  

NASA Astrophysics Data System (ADS)

Context. Separators, which are in many ways the three-dimensional equivalent to two-dimensional nulls, are important sites for magnetic reconnection. Magnetic reconnection occurs in strong current layers which have very short length scales. Aims: The aim of this work is to explore the nature of current layers around separators. A separator is a special field line which lies along the intersection of two separatrix surfaces and forms the boundary between four topologically distinct flux domains. In particular, here the current layer about a separator that joins two 3D nulls and lies along the intersection of their separatrix surfaces is investigated. Methods: A magnetic configuration containing a single separator embedded in a uniform plasma with a uniform electric current parallel to the separator is considered. This initial magnetic setup, which is not in equilibrium, relaxes in a non-resistive manner to form an equilibrium. The relaxation is achieved using the 3D MHD code, Lare3d, with resistivity set to zero. A series of experiments with varying initial current are run to investigate the characteristics of the resulting current layers present in the final (quasi-)equilibrium states. Results: In each experiment, the separator collapses and a current layer forms along it. The dimensions and strength of the current layer increase with initial current. It is found that separator current layers formed from current parallel to the separator are twisted. Also the collapse of the separator is a process that evolves like an infinite-time singularity where the length, width and peak current in the layer grow slowly whilst the depth of the current layer decreases.

Stevenson, J. E. H.; Parnell, C. E.; Priest, E. R.; Haynes, A. L.

2015-01-01

382

Sink-float ferrofluid separator applicable to full scale nonferrous scrap separation  

NASA Technical Reports Server (NTRS)

Design and performance of a ferrofluid levitation separator for recovering nonferrous metals from shredded automobiles are reported. The scrap separator uses an electromagnet to generate a region of constant density within a pool of ferrofluid held between the magnetic poles; a saturated kerosene base ferrofluid as able to float all common industrial metals of interest. Conveyors move the scrap into the ferrofluid for separation according to density. Results of scrap mixture separation studies establish the technical feasibility of relatively pure aluminum alloy and zinc alloy fractions from shredded automobile scrap by this ferrofluid levitation process. Economic projections indicate profitable operation for shredders handling more than 300 cars per day.

1973-01-01

383

Magnetic and Mechanical Analysis of the HQ Model Quadrupole Designs for LARP  

SciTech Connect

Insertion quadrupoles with large bore and high gradient are required to upgrade the luminosity of the Large Hadron Collider (LHC). The US LHC Accelerator Research Program is developing Nb{sub 3}Sn technology for the upgrade. This effort includes a series of 1 m long Technology Quadrupoles (TQ), to demonstrate the reproducibility at moderate field, and High-gradient Quadrupoles (HQ) to explore the magnet performance limits in terms of peak fields, forces and stresses. The HQ models are expected to achieve peak fields of 15 T or higher. A coil aperture of 90 mm, corresponding to gradients above 300 T/m, was chosen as the baseline. Peak stresses above 150 MPa are expected. Progress on the magnetic and mechanical design of the HQ models will be reported.

Felice, Helene; Caspi, Shlomo; Ferracin, Paolo; Kashikhin, Vadim; Novitski, Igor; Sabbi, GianLuca; Zlobin, Alexander

2008-06-01

384

Separation of transplutonium elements.  

PubMed

A critical review of the group separation of tervalent lanthanides and actinides and of the separation of individual transplutonium elements is presented. The theoretical principles involved are also discussed. PMID:18959895

Starý, J

1966-03-01

385

Composite battery separator  

Microsoft Academic Search

This patent describes a liquid-containing electrochemical cell wherein positive and negative electrode plates separated by an insulating separator are urged towards one another under pressure. The improved separator comprises: a highly porous, non-compressible sheet of an insulating material wherein the sheet is formed of; parallel, spaced, first straight linear elements defining a first surface on one side of the sheet;

D. B. Edwards; W. E. Rippel

1987-01-01

386

Meniscus membranes for separations  

DOEpatents

Gas separation membranes, especially meniscus-shaped membranes for gas separations are disclosed together with the use of such meniscus-shaped membranes for applications such as thermal gas valves, pre-concentration of a gas stream, and selective pre-screening of a gas stream. In addition, a rapid screening system for simultaneously screening polymer materials for effectiveness in gas separation is provided.

Dye, Robert C. (Irvine, CA); Jorgensen, Betty (Jemez Springs, NM); Pesiri, David R. (Aliso Viejo, CA)

2004-01-27

387

Meniscus Membranes For Separation  

DOEpatents

Gas separation membranes, especially meniscus-shaped membranes for gas separations are disclosed together with the use of such meniscus-shaped membranes for applications such as thermal gas valves, pre-concentration of a gas stream, and selective pre-screening of a gas stream. In addition, a rapid screening system for simultaneously screening polymer materials for effectiveness in gas separation is provided.

Dye, Robert C. (Irvine, CA); Jorgensen, Betty (Jemez Springs, NM); Pesiri, David R. (Aliso Viejo, CA)

2005-09-20

388

Zirconium isotope separation  

SciTech Connect

A method of separating zirconium isotopes by converting the zirconium to its iodide salt prior to separation by usual isotope methods is disclosed. After separation the desired isotopes are converted from the salt to the metal by the van Arkel-de Boer iodide process.

Siddall, M.B.

1984-12-11

389

Separations Using Zeolite Membranes  

Microsoft Academic Search

This overview describes some of the main features of the use of zeolite membranes for separation applications. Four different types of separations are considered: separation of non-adsorbing compounds, of organic molecules, of permanent gases from vapors, and of water (or polar molecules) from organic (or non-polar) species. Several factors, such as the limiting pore size and pore size distribution, surface

Joaquín Coronas; Jesús Santamaría

1999-01-01

390

Equivariant adaptive source separation  

Microsoft Academic Search

Source separation consists of recovering a set of independent signals when only mixtures with unknown coefficients are observed. This paper introduces a class of adaptive algorithms for source separation that implements an adaptive version of equivariant estimation and is henceforth called equivariant adaptive separation via independence (EASI). The EASI algorithms are based on the idea of serial updating. This specific

Jean-françois Cardoso; Beate Hvam Laheld

1996-01-01

391

The nature of separator current layers in MHS equilibria I. Current parallel to the separator  

E-print Network

Separators, which are in many ways the three-dimensional equivalent to two-dimensional nulls, are important sites for magnetic reconnection. Magnetic reconnection occurs in strong current layers which have very short length scales. The aim of this work is to explore the nature of current layers around separators. A separator is a special field line which lies along the intersection of two separatrix surfaces and forms the boundary between four topologically distinct flux domains. In particular, here the current layer about a separator that joins two 3D nulls and lies along the intersection of their separatrix surfaces is investigated. A magnetic configuration containing a single separator embedded in a uniform plasma with a uniform electric current parallel to the separator is considered. This initial magnetic setup, which is not in equilibrium, relaxes in a non-resistive manner to form an equilibrium. The relaxation is achieved using the 3D MHD code, Lare3d, with resistivity set to zero. A series of experime...

Stevenson, J E H; Priest, E R; Haynes, A L

2014-01-01

392

Separation of variables in the Gaudin model  

Microsoft Academic Search

We separate variables for the Gaudin model (degenerate case of an integrable quantum magnet SU(2) -chain) by means of an explicit change of coordinates. We get a description of the space of states in the language of ideals in polynomial rings. The structure of the eigenfunctions is studied.

E. K. Sklyanin

1989-01-01

393

Separation control at hydrofoils using Lorentz forces  

Microsoft Academic Search

Lorentz forces originating from surface-mounted actuators of permanent magnets and electrodes in weakly conducting fluids like seawater can be used to control flow separation at hydrofoils. The numerical results presented here are based on direct numerical simulation in the laminar flow regime, limited to Reynolds numbers of O(500). Control by steady forcing at the suction side and by oscillatory forcing

G. Mutschke; G. Gerbeth; T. Albrecht; R. Grundmann

2006-01-01

394

The Superconducting Interaction Region Magnet System for the CESRhttp://www.lns.cornell.edu Phase III Upgrade  

NASA Astrophysics Data System (ADS)

Deep inside the CLEO III detector will be two pairs of new high gradient superconducting interaction region magnets. Their close proximity to the interaction point, short focal lengths and large warm bore diameter are all optimized for the highest possible luminosity using crossing angles and bunch trains. Superposed with the main quadrupole fields are fields from skew quadrupole coils for solenoid coupling compensation, and fields from horizontal dipole coils for correction of small vertical misalignments of the magnetic centers. The magnet cryostats are held by active positioning systems for beam-based mechanical alignment. The magnet system is being designed and manufactured by Tesla Engineering Ltd of England.

Welch, James J.; Dugan, Gerald F.; Emery, Nordberg; Rice, David

1997-05-01

395

Microfluidic biosensing systems using magnetic nanoparticles.  

PubMed

In recent years, there has been rapidly growing interest in developing hand held, sensitive and cost-effective on-chip biosensing systems that directly translate the presence of certain bioanalytes (e.g., biomolecules, cells and viruses) into an electronic signal. The impressive and rapid progress in micro- and nanotechnology as well as in biotechnology enables the integration of a variety of analytical functions in a single chip. All necessary sample handling and analysis steps are then performed within the chip. Microfluidic systems for biomedical analysis usually consist of a set of units, which guarantees the manipulation, detection and recognition of bioanalytes in a reliable and flexible manner. Additionally, the use of magnetic fields for performing the aforementioned tasks has been steadily gaining interest. This is because magnetic fields can be well tuned and applied either externally or from a directly integrated solution in the biosensing system. In combination with these applied magnetic fields, magnetic nanoparticles are utilized. Some of the merits of magnetic nanoparticles are the possibility of manipulating them inside microfluidic channels by utilizing high gradient magnetic fields, their detection by integrated magnetic microsensors, and their flexibility due to functionalization by means of surface modification and specific binding. Their multi-functionality is what makes them ideal candidates as the active component in miniaturized on-chip biosensing systems. In this review, focus will be given to the type of biosening systems that use microfluidics in combination with magnetoresistive sensors and detect the presence of bioanalyte tagged with magnetic nanoparticles. PMID:24022689

Giouroudi, Ioanna; Keplinger, Franz

2013-01-01

396

Approaches to improve separation efficiency of eddy current separation for recovering aluminum from waste toner cartridges.  

PubMed

Separation efficiency of eddy current separation (ECS) is low (about 85%) in industrial application for recovering aluminum from crushed waste toner cartridges. Influencing factors of ECS were studied to improve the separation efficiency. Operation factors were researched by orthogonal experiment of ECS on investigating the separation distance between aluminum and plastic flakes. The results indicated the difference (?R-v) between feeding speed (v) and rotation speed (?) of magnetic drum (radius: R) was critical factor of influencing the separation efficiency, feeding speed (v) was general factor, and collecting position (H) was subordinate factor. Separation efficiency decreased as the increasing of v, and increased as the increasing of (?R-v). 0.9 m was the optimal value of H in the orthogonal experiment. Influencing factors of particle characteristics and machine structure were studied by newly established models for computing the separation distance between aluminum and plastic flake in ECS. The results indicated changing of particle size would influence the separation efficiency greater than ? and particle shape. Separation efficiency will increase as the increasing of particle size and ?. Shape of circle is beneficial to improve separation efficiency. Finally, approaches to improve separation efficiency of ECS were presented. PMID:22571825

Ruan, Jujun; Xu, Zhenming

2012-06-01

397

Cell clarification and size separation using continuous countercurrent magnetophoresis.  

PubMed

Nonmagnetic microparticles (e.g., cells, polymer beads) immersed in a magnetic fluid (ferrofluid) under a nonuniform magnetic field experience a magnetophoretic force in the direction of decreasing magnetic field strength. This phenomenon was exploited in the development of a continuous magnetophoretic countercurrent separation for the removal and concentration of micron-sized particles from aqueous suspensions, and in particular as a viable approach for cell clarification of raw fermentation broth. A magnetic fluid is added to the cell suspension, the mixture is introduced to the magnetic separator, which consists of an open flow tube passing between pairs of magnets that move in a direction counter to the flow of the suspension. The cells are pushed ahead of the magnet pairs owing to the magnetophoretic forces acting on them, collected in a tube upstream of the feed injection point, and removed as a concentrated suspension for further treatment. PMID:21608138

Bucak, Seyda; Sharpe, Sonja; Kuhn, Simon; Hatton, T Alan

2011-01-01

398

Membrane separation systems  

SciTech Connect

This book discusses developments and future directions in the field of membrane separation systems. It describes research needed to bring energy-saving membrane separation processes to technical and commercial readiness for commercial acceptance within the next 5 to 20 years. The assessment was conducted by a group of six internationally known membrane separations experts who examined the worldwide status of research in seven major membrane areas. These encompassed four mature technology areas: reverse osmosis, microfiltration, ultrafiltration, and electrodialysis; two developing areas: gas separation and pervaporation; and one emerging technology; facilitated transport.

Baker, R.W.; Cussler, E.L.; Eykamp, W.; Koros, W.J.; Riley, R.L.; Strathman, R.H.

1991-01-01

399

separationsNOW.com  

NSDL National Science Digital Library

This separation science and chromatography Web portal from publisher John Wiley and Sons expects "to become the definitive separation science resource on the Internet, offering a wealth of valuable information, resources, and services." separationsNOW addresses electrophoresis, chromatography, and other separation techniques with frequently-updated news, Web links, conference announcements, technique-specific discussion forums, educational features, and much more. Free registration is required to access advanced features, such as a selection of free full-text articles in the online library.

2003-01-01

400

separationsNOW.com  

NSDL National Science Digital Library

This separation science and chromatography Web portal from publisher John Wiley and Sons expects "to become the definitive separation science resource on the Internet, offering a wealth of valuable information, resources, and services." separationsNOW addresses electrophoresis, chromatography, and other separation techniques with frequently-updated news, Web links, conference announcements, technique-specific discussion forums, educational features, and much more. Free registration is required to access advanced features, such as a selection of free full-text articles in the online library.

401

Freely oriented portable superconducting magnet  

DOEpatents

A freely oriented portable superconducting magnet is disclosed. Coolant is supplied to the superconducting magnet from a repository separate from the magnet, enabling portability of the magnet. A plurality of support assemblies structurally anchor and thermally isolate the magnet within a thermal shield. A plurality of support assemblies structurally anchor and thermally isolate the thermal shield within a vacuum vessel. The support assemblies restrain movement of the magnet resulting from energizing and cooldown, as well as from changes in orientation, enabling the magnet to be freely orientable.

Schmierer, Eric N. (Los Alamos, NM); Prenger, F. Coyne (Los Alamos, NM); Hill, Dallas D. (Los Alamos, NM)

2010-01-12

402

Separability and dynamical symmetry of Quantum Dots  

SciTech Connect

The separability and Runge–Lenz-type dynamical symmetry of the internal dynamics of certain two-electron Quantum Dots, found by Simonovi? et al. (2003), are traced back to that of the perturbed Kepler problem. A large class of axially symmetric perturbing potentials which allow for separation in parabolic coordinates can easily be found. Apart from the 2:1 anisotropic harmonic trapping potential considered in Simonovi? and Nazmitdinov (2013), they include a constant electric field parallel to the magnetic field (Stark effect), the ring-shaped Hartmann potential, etc. The harmonic case is studied in detail. -- Highlights: • The separability of Quantum Dots is derived from that of the perturbed Kepler problem. • Harmonic perturbation with 2:1 anisotropy is separable in parabolic coordinates. • The system has a conserved Runge–Lenz type quantity.

Zhang, P.-M., E-mail: zhpm@impcas.ac.cn [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou (China); Zou, L.-P., E-mail: zoulp@impcas.ac.cn [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou (China); Horvathy, P.A., E-mail: horvathy@lmpt.univ-tours.fr [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou (China); Laboratoire de Mathématiques et de Physique Théorique, Tours University (France); Gibbons, G.W., E-mail: G.W.Gibbons@damtp.cam.ac.uk [Department of Applied Mathematics and Theoretical Physics, Cambridge University, Cambridge (United Kingdom)

2014-02-15

403

Micro- and nanotechnology in cell separation  

PubMed Central

This review describes recent work in cell separation using micro- and nanoscale technologies. These devices offer several advantages over conventional, macroscale separation systems in terms of sample volumes, low cost, portability, and potential for integration with other analytical techniques. More importantly, and in the context of modern medicine, these technologies provide tools for point-of-care diagnostics, drug discovery, and chemical or biological agent detection. This review describes work in five broad categories of cell separation based on (1) size, (2) magnetic attraction, (3) fluorescence, (4) adhesion to surfaces, and (5) new emerging technologies. The examples in each category were selected to illustrate separation principles and technical solutions as well as challenges facing this rapidly emerging field. PMID:17722258

Radisic, Milica; Iyer, Rohin K; Murthy, Shashi K

2006-01-01

404

Magnetic Flux Emergence Along the Solar Cycle  

NASA Astrophysics Data System (ADS)

Flux emergence plays an important role along the solar cycle. Magnetic flux emergence builds sunspot groups and solar activity. The sunspot groups contribute to the large scale behaviour of the magnetic field over the 11 year cycle and the reversal of the North and South magnetic polarity every 22 years. The leading polarity of sunspot groups is opposite in the North and South hemispheres and reverses for each new solar cycle. However the hemispheric rule shows the conservation of sign of the magnetic helicity with positive and negative magnetic helicity in the South and North hemispheres, respectively. MHD models of emerging flux have been developed over the past twenty years but have not yet succeeded to reproduce solar observations. The emergence of flux occurs through plasma layers of very high gradients of pressure and changing of modes from a large ? to a low ? plasma (<1). With the new armada of high spatial and temporal resolution instruments on the ground and in space, emergence of magnetic flux is observed in tremendous detail and followed during their transit through the upper atmosphere. Signatures of flux emergence in the corona depend on the pre-existing magnetic configuration and on the strength of the emerging flux. We review in this paper new and established models as well as the recent observations.

Schmieder, B.; Archontis, V.; Pariat, E.

2014-12-01

405

Separations inside a cube  

E-print Network

Two points are randomly selected inside a three-dimensional euclidian cube. The value l of their separation lies somewhere between zero and the length of a diagonal of the cube. The probability density P(l) of the separation is obtained analytically. Also a Monte Carlo computer simulation is performed, showing good agreement with the formulas obtained.

A. F. F. Teixeira

2001-12-28

406

The effect of machine and material parameters on rare earth roller separation  

E-print Network

This study addresses the affect of machine and material factors on the separation of PET plastic and aluminum on the Rare Earth Roller magnetic separator. The purposes of this study are to gain a better understanding of ...

Hu, Esther, S.B. Massachusetts Institute of Technology

2009-01-01

407

Separators for flywheel rotors  

DOEpatents

A separator forms a connection between the rotors of a concentric rotor assembly. This separator allows for the relatively free expansion of outer rotors away from inner rotors while providing a connection between the rotors that is strong enough to prevent disassembly. The rotor assembly includes at least two rotors referred to as inner and outer flywheel rings or rotors. This combination of inner flywheel ring, separator, and outer flywheel ring may be nested to include an arbitrary number of concentric rings. The separator may be a segmented or continuous ring that abuts the ends of the inner rotor and the inner bore of the outer rotor. It is supported against centrifugal loads by the outer rotor and is affixed to the outer rotor. The separator is allowed to slide with respect to the inner rotor. It is made of a material that has a modulus of elasticity that is lower than that of the rotors. 10 figs.

Bender, D.A.; Kuklo, T.C.

1998-07-07

408

Isothermal separation processes  

NASA Technical Reports Server (NTRS)

The isothermal processes of membrane separation, supercritical extraction and chromatography were examined using availability analysis. The general approach was to derive equations that identified where energy is consumed in these processes and how they compare with conventional separation methods. These separation methods are characterized by pure work inputs, chiefly in the form of a pressure drop which supplies the required energy. Equations were derived for the energy requirement in terms of regular solution theory. This approach is believed to accurately predict the work of separation in terms of the heat of solution and the entropy of mixing. It can form the basis of a convenient calculation method for optimizing membrane and solvent properties for particular applications. Calculations were made on the energy requirements for a membrane process separating air into its components.

England, C.

1982-01-01

409

International Magnetics Conference, Hamburg, West Germany, April 9-13, 1984, Proceedings  

Microsoft Academic Search

Current research on magnetism and magnetic materials and their applications is presented in reviews and reports and illustrated with graphs, diagrams, photographs, and micrographs. Subject areas covered include magnetic recording (physics, media, heads, and systems), magnetic sensors, magnetooptics, bubble devices, magnetic separation, microwaves, amorphous materials, soft magnetic materials, permanent magnets, superconductors, magnetic levitation, and magnetometry. Consideration is given to ferrofluids,

B. E. MacNeal; R. E. Fontana Jr.; J. C. Suits

1984-01-01

410

Formulation and In Vitro Characterization of Composite Biodegradable Magnetic Nanoparticles for Magnetically Guided Cell Delivery  

PubMed Central

Purpose Cells modified with magnetically responsive nanoparticles (MNP) can provide the basis for novel targeted therapeutic strategies. However, improvements are required in the MNP design and cell treatment protocols to provide adequate magnetic properties in balance with acceptable cell viability and function. This study focused on select variables controlling the uptake and cell compatibility of biodegradable polymer-based MNP in cultured endothelial cells. Methods Fluorescent-labeled MNP were formed using magnetite and polylactide as structural components. Their magnetically driven sedimentation and uptake were studied fluorimetrically relative to cell viability in comparison to non-magnetic control conditions. The utility of surface-activated MNP forming affinity complexes with replication-deficient adenovirus (Ad) for transduction achieved concomitantly with magnetic cell loading was examined using the green fluorescent protein reporter. Results A high-gradient magnetic field was essential for sedimentation and cell binding of albumin-stabilized MNP, the latter being rate-limiting in the MNP loading process. Cell loading up to 160 pg iron oxide per cell was achievable with cell viability >90%. Magnetically driven uptake of MNP-Ad complexes can provide high levels of transgene expression potentially useful for a combined cell/gene therapy. Conclusions Magnetically responsive endothelial cells for targeted delivery applications can be obtained rapidly and efficiently using composite biodegradable MNP. PMID:22274555

Alferiev, Ivan S.; Fishbein, Ilia; Tengood, Jillian E.; Folchman-Wagner, Zoë; Forbes, Scott P.; Levy, Robert J.

2012-01-01

411

Flow Chart for Mineral Separation from Granitic Rocks.  

ERIC Educational Resources Information Center

Provided is a flow chart for the separation and purification of major, minor, and accessory minerals from granitic rocks. With careful use of heavy liquids, and a Franz Isodynamic Magnetic Separator, it is possible to obtain mineral concentrates with a purity of 95 percent or better. (Author/RH)

Mursky, Gregory

1987-01-01

412

Separator morphology and null location dependence on clock angle in global magnetospheric simulations  

NASA Astrophysics Data System (ADS)

Magnetic separators (single magnetic field lines that separate regions of all different magnetic topologies) and magnetic nulls are important to identify at the dayside magnetopause because they provide valuable information about the global magnetic topology and where magnetic reconnection is likely to occur. Relatively few studies have addressed the changes to the separators and nulls as a function of interplanetary magnetic field (IMF) clock angle. In this study, we present a new highly accurate method for tracing magnetic separators. We confirm the technique with separators from a vacuum superposition model of a dipolar magnetic field added to a uniform background field. Then, we trace separators in global magnetohydrodynamic (MHD) simulations using the three-dimensional BATS-R-US code with a uniform plasma resistivity. The magnetic nulls and separators are found in distinct simulations with IMF clock angles ranging from 0 (parallel) to 180 degrees (antiparallel) in increments of 30 degrees. Trends in the location of the nulls and the structural morphology of the separators are tabulated as a function of clock angle and compared to the vacuum superposition model. While there are many qualitative similarities, deviations of the two models are also noted.

Komar, C. M.; Cassak, P.; Dorelli, J.; Glocer, A.; Kuznetsova, M. M.

2012-12-01

413

Magnet pole tips  

DOEpatents

An improved magnet more easily provides a radially increasing magnetic field, as well as reduced fringe field and requires less power for a given field intensity. The subject invention comprises a pair of spaced, opposed magnetic poles which further comprise a pair of pole roots, each having a pole tip attached to its center. The pole tips define the gap between the magnetic poles and at least a portion of each pole tip is separated from its associated pole root. The separation begins at a predetermined distance from the center of the pole root and increases with increasing radial distance while being constant with azimuth within that portion. Magnets in accordance with the subject invention have been found to be particularly advantageous for use in large isochronous cyclotrons.

Thorn, C.E.; Chasman, C.; Baltz, A.J.

1981-11-19

414

Magnet pole tips  

DOEpatents

An improved magnet which more easily provides a radially increasing magnetic field, as well as reduced fringe field and requires less power for a given field intensity. The subject invention comprises a pair of spaced, opposed magnetic poles which further comprise a pair of pole roots, each having a pole tip attached to its center. The pole tips define the gap between the magnetic poles and at least a portion of each pole tip is separated from its associated pole root. The separation begins at a predetermined distance from the center of the pole root and increases with increasing radial distance while being constant with azimuth within that portion. Magnets in accordance with the subject invention have been found to be particularly advantageous for use in large isochronous cyclotrons.

Thorn, Craig E. (Wading River, NY); Chasman, Chellis (Setauket, NY); Baltz, Anthony J. (Coram, NY)

1984-04-24

415

Novel Separation of Actinides  

SciTech Connect

The separation of actinides and other elements of interest for nuclear forensics and threat reduction is currently performed using decades-old chemistries and ion-exchange columns. We propose to determine the technical feasibility of a novel method for separating actinide ions in solution. This method is based upon isotachophoresis (ITP), which has been applied in the purification of pharmaceuticals and other biochemical applications. This technique has the potential to separate inorganic ions more effectively than existing methods, which is key to analyzing very small samples. We will perform a quantitative assessment of the effectiveness of specific isotachophoretic approaches including predicting the physical and chemical properties, such as ion mobility, of inorganic ions under specific solvent conditions using a combination of ab initio calculations and semi-empirical methods. We expect to obtain a thorough understanding of the analytical systems parameters under which ITP is most effective for the separation of inorganic samples, including the influence of the double layer surrounding actinide ions, the Debye length for different ions and ion complexes, and Debye-Hueckel limits. Inorganic separations are key to nuclear forensics for countering terrorism and nuclear proliferation. If found to be feasible and potentially superior to currently used separation approaches, ITP could provide the conceptual basis for an improved means to separate samples of nuclear explosion debris for nuclear forensic analysis, in support of the Laboratory's missions in homeland and national security.

Mariella, R

2011-02-17

416

Rotary drum separator system  

NASA Technical Reports Server (NTRS)

A rotary phase separator system generally includes a step-shaped rotary drum separator (RDS) and a motor assembly. The aspect ratio of the stepped drum minimizes power for both the accumulating and pumping functions. The accumulator section of the RDS has a relatively small diameter to minimize power losses within an axial length to define significant volume for accumulation. The pumping section of the RDS has a larger diameter to increase pumping head but has a shorter axial length to minimize power losses. The motor assembly drives the RDS at a low speed for separating and accumulating and a higher speed for pumping.

Barone, Michael R. (Inventor); Murdoch, Karen (Inventor); Scull, Timothy D. (Inventor); Fort, James H. (Inventor)

2009-01-01

417

Materials separation by dielectrophoresis  

NASA Technical Reports Server (NTRS)

The feasibility of vacuum dielectrophoresis as a method for particulate materials separation in a microgravity environment was investigated. Particle separations were performed in a specially constructed miniature drop-tower with a residence time of about 0.3 sec. Particle motion in such a system is independent of size and based only on density and dielectric constant, for a given electric field. The observed separations and deflections exceeded the theoretical predictions, probably due to multiparticle effects. In any case, this approach should work well in microgravity for many classes of materials, with relatively simple apparatus and low weight and power requirements.

Sagar, A. D.; Rose, R. M.

1988-01-01

418

Enhance separations with electricity  

SciTech Connect

To satisfy growing environmental regulations, control energy costs, or just to stay competitive, one must improve existing separation technologies and make them more efficient. New challenges in food processing and requirements for novel purification technologies in the biotech industry also will require more efficient separation techniques. This paper discusses some enhanced separation processes based on the application of an electric field in the combined-fields approach. In a combined-fields approach, the emphasis is on the generation of additional driving forces to work simultaneously with the conventional driving force of the process. Here the authors concentrate on the application of an electric field to generate the additional driving force.

Muralidhara, H.S.

1994-05-01

419

Chromatographic hydrogen isotope separation  

DOEpatents

Intermetallic compounds with the CaCu.sub.5 type of crystal structure, particularly LaNiCo.sub.4 and CaNi.sub.5, exhibit high separation factors and fast equilibrium times and therefore are useful for packing a chromatographic hydrogen isotope separation colum. The addition of an inert metal to dilute the hydride improves performance of the column. A large scale mutli-stage chromatographic separation process run as a secondary process off a hydrogen feedstream from an industrial plant which uses large volumes of hydrogen can produce large quantities of heavy water at an effective cost for use in heavy water reactors.

Aldridge, Frederick T. (Livermore, CA)

1981-01-01

420

Magnetic properties in graphene-graphane superlattices  

E-print Network

The magnetic properties of graphene-graphane superlattices with zigzag interfaces and separately varying widths are investigated by first-principles density functional calculations. It is demonstrated that magnetic states ...

Lee, Joo-Hyoung

421

Diamagnetic capture mode magnetophoretic microseparator for blood cells  

Microsoft Academic Search

This paper presents the characterization of a continuous diamagnetic capture (DMC) mode magnetophoretic microseparator for separating red and white blood cells from diluted whole blood based on their native magnetic properties. The DMC microseparator separated the blood cells using a high-gradient magnetic separation (HGMS) method without the use of additives such as magnetic beads. The microseparator was fabricated using microfabrication

Ki-Ho Han; A. Bruno Frazier

2005-01-01

422

Gas-separation process  

DOEpatents

A process for separating c