Science.gov

Sample records for human projected area

  1. Pilot Communication Research Project Utilizing the Human Relations Area Files (HRAF).

    ERIC Educational Resources Information Center

    Corder, Lloyd E.; And Others

    This paper describes the evolution of a group research project undertaken by six communication graduate students, using the Human Relations Area Files (HRAF), a collection of primary source materials on over 250 predominantly pre-literate cultures representing all major areas of the world. The paper narrates the students' research processes, from…

  2. Human projected area factors for detailed direct and diffuse solar radiation analysis.

    PubMed

    Kubaha, K; Fiala, D; Toftum, J; Taki, A H

    2004-11-01

    Projected area factors for individual segments of the standing and sedentary human body were modelled for both direct and diffuse solar radiation using detailed 3D geometry and radiation models. The local projected area factors with respect to direct short-wave radiation are a function of the solar azimuth angle (alpha) between 0 degrees < alpha<360 degrees and the solar altitude (beta) angles between -90 degrees < beta<+90 degrees . In case of diffuse solar radiation from the isotropic sky the local human projected area factors were modelled as a function of the ground albedo (rho) ranging between 0< rho<1. The model was validated against available experimental data and showed good general agreement with projected area factors measured for both the human body as a whole and for local quantities. Scientists can use the equations to predict the inhomogeneous irradiation and absorption of direct and diffuse solar radiation and UV-radiation at surfaces of the human body. In conjunction with detailed multi-node models of human thermoregulation the equations can be used to predict the physiological implications of solar radiation and outdoor weather conditions on humans. PMID:15278684

  3. Human Genome Project

    SciTech Connect

    Block, S.; Cornwall, J.; Dally, W.; Dyson, F.; Fortson, N.; Joyce, G.; Kimble, H. J.; Lewis, N.; Max, C.; Prince, T.; Schwitters, R.; Weinberger, P.; Woodin, W. H.

    1998-01-04

    The study reviews Department of Energy supported aspects of the United States Human Genome Project, the joint National Institutes of Health/Department of Energy program to characterize all human genetic material, to discover the set of human genes, and to render them accessible for further biological study. The study concentrates on issues of technology, quality assurance/control, and informatics relevant to current effort on the genome project and needs beyond it. Recommendations are presented on areas of the genome program that are of particular interest to and supported by the Department of Energy.

  4. The human genome project.

    PubMed Central

    Olson, M V

    1993-01-01

    The Human Genome Project in the United States is now well underway. Its programmatic direction was largely set by a National Research Council report issued in 1988. The broad framework supplied by this report has survived almost unchanged despite an upheaval in the technology of genome analysis. This upheaval has primarily affected physical and genetic mapping, the two dominant activities in the present phase of the project. Advances in mapping techniques have allowed good progress toward the specific goals of the project and are also providing strong corollary benefits throughout biomedical research. Actual DNA sequencing of the genomes of the human and model organisms is still at an early stage. There has been little progress in the intrinsic efficiency of DNA-sequence determination. However, refinements in experimental protocols, instrumentation, and project management have made it practical to acquire sequence data on an enlarged scale. It is also increasingly apparent that DNA-sequence data provide a potent means of relating knowledge gained from the study of model organisms to human biology. There is as yet little indication that the infusion of technology from outside biology into the Human Genome Project has been effectively stimulated. Opportunities in this area remain large, posing substantial technical and policy challenges. PMID:8506271

  5. Visible Human Project

    MedlinePlus

    ... Mobile Gallery Site Navigation Home The Visible Human Project ® Overview The Visible Human Project ® is an outgrowth of the NLM's 1986 Long- ... The long-term goal of the Visible Human Project ® is to produce a system of knowledge structures ...

  6. Humane Education Projects Handbook.

    ERIC Educational Resources Information Center

    Junior League of Ogden, UT.

    This handbook was developed to promote interest in humane education and to encourage the adoption of humane education projects. Although specifically designed to assist Junior Leagues in developing such projects, the content should prove valuable to animal welfare organizations, zoos, aquariums, nature centers, and other project-oriented groups…

  7. Project analysis and integration area

    NASA Technical Reports Server (NTRS)

    1986-01-01

    The objective of the Project Analysis and Integration Area (PA&I) is to support the planning, analysis, integration, and decision making activities of the Flat-plate Solar Array FSA) Project. Accordingly, PA&I supports the Project by developing and documenting Project plans based, in part, on the technical and economic assessments performed by PA&I of the various technical options. Goals for module technical performance and costs, derived from National Photovoltaics Program goals, are established by PA&I for each of the major technical activities in the Project. Assessments of progress toward achievement of goals are made to guide decision making within the Project.

  8. The human genome project

    SciTech Connect

    Bell, G.I.

    1991-06-01

    The Human Genome Project will obtain high-resolution genetic and physical maps of each human chromosome and, somewhat later, of the complete nucleotide sequence of the deoxyribonucleic acid (DNA) in a human cell. The talk will begin with an extended introduction to explain the Project to nonbiologists and to show that map construction and sequence determination require extensive computation in order to determine the correct order of the mapped entities and to provide estimates of uncertainty. Computational analysis of the sequence data will become an increasingly important part of the project, and some computational challenges are described. 5 refs.

  9. The Human Toxome Project

    EPA Science Inventory

    The Human Toxome project, funded as an NIH Transformative Research grant 2011--‐ 2016, is focused on developing the concepts and the means for deducing, validating, and sharing molecular Pathways of Toxicity (PoT). Using the test case of estrogenic endocrine disruption, the respo...

  10. The human toxome project.

    PubMed

    Bouhifd, Mounir; Andersen, Melvin E; Baghdikian, Christina; Boekelheide, Kim; Crofton, Kevin M; Fornace, Albert J; Kleensang, Andre; Li, Henghong; Livi, Carolina; Maertens, Alexandra; McMullen, Patrick D; Rosenberg, Michael; Thomas, Russell; Vantangoli, Marguerite; Yager, James D; Zhao, Liang; Hartung, Thomas

    2015-01-01

    The Human Toxome Project, funded as an NIH Transformative Research grant 2011-2016, is focused on developing the concepts and the means for deducing, validating and sharing molecular pathways of toxicity (PoT). Using the test case of estrogenic endocrine disruption, the responses of MCF-7 human breast cancer cells are being phenotyped by transcriptomics and mass-spectroscopy-based metabolomics. The bioinformatics tools for PoT deduction represent a core deliverable. A number of challenges for quality and standardization of cell systems, omics technologies and bioinformatics are being addressed. In parallel, concepts for annotation, validation and sharing of PoT information, as well as their link to adverse outcomes, are being developed. A reasonably comprehensive public database of PoT, the Human Toxome Knowledge-base, could become a point of reference for toxicological research and regulatory test strategies. PMID:25742299

  11. The Human Toxome Project

    PubMed Central

    Bouhifd, Mounir; Andersen, Melvin E.; Baghdikian, Christina; Boekelheide, Kim; Crofton, Kevin M.; Fornace, Albert J.; Kleensang, Andre; Li, Henghong; Livi, Carolina; Maertens, Alexandra; McMullen, Patrick D.; Rosenberg, Michael; Thomas, Russell; Vantangoli, Marguerite; Yager, James D.; Zhao, Liang; Hartung, Thomas

    2016-01-01

    Summary The Human Toxome Project, funded as an NIH Transformative Research grant 2011–2016, is focused on developing the concepts and the means for deducing, validating and sharing molecular pathways of toxicity (PoT). Using the test case of estrogenic endocrine disruption, the responses of MCF-7 human breast cancer cells are being phenotyped by transcriptomics and mass-spectrometry-based metabolomics. The bioinformatics tools for PoT deduction represent a core deliverable. A number of challenges for quality and standardization of cell systems, omics technologies and bioinformatics are being addressed. In parallel, concepts for annotation, validation and sharing of PoT information, as well as their link to adverse outcomes, are being developed. A reasonably comprehensive public database of PoT, the Human Toxome Knowledge-base, could become a point of reference for toxicological research and regulatory test strategies. PMID:25742299

  12. The Supplementary Motor Area Exerts a Tonic Excitatory Influence on Corticospinal Projections to Phrenic Motoneurons in Awake Humans

    PubMed Central

    Hudson, Anna L.; Raux, Mathieu; Allard, Étienne; Similowski, Thomas

    2013-01-01

    Introduction In humans, cortical mechanisms can interfere with autonomic breathing. Respiratory-related activation of the supplementary motor area (SMA) has been documented during voluntary breathing and in response to inspiratory constraints. The SMA could therefore participate in the increased resting state of the respiratory motor system during wake (i.e. "wakefulness drive to breathe"). Methods The SMA was conditioned by continuous theta burst magnetic stimulation (cTBS, inhibitory) and 5 Hz conventional rTMS (5 Hz, excitatory). The ensuing effects were described in terms of the diaphragm motor evoked response (DiMEPs) to single-pulse transcranial magnetic stimulation over the motor cortex. DiMEPs were recorded at baseline, and at 3 time-points ("post1", "post2", "post3") up to 15 minutes following conditioning of the SMA. Results cTBS reduced the amplitude of DiMEPs from 327.5±159.8 µV at baseline to 243.3±118.7 µV, 217.8±102.9 µV and 240.6±123.9 µV at post 1, post 2 and post 3, respectively (F = 6.341, p = 0.002). 5 Hz conditioning increased the amplitude of DiMEPs from 184.7±96.5 µV at baseline to 270.7±135.4 µV at post 3 (F = 4.844, p = 0.009). Conclusions The corticospinal pathway to the diaphragm can be modulated in both directions by conditioning the SMA. This suggests that the baseline respiratory activity of the SMA represents an equipoise from which it is possible to move in either direction. The resting corticofugal outflow from the SMA to phrenic motoneurones that this study evidences could putatively contribute to the wakefulness drive to breathe. PMID:23614046

  13. The Human Variome Project.

    PubMed

    Burn, John; Watson, Michael

    2016-06-01

    The practical realization of genomics has meant a growing realization that variant interpretation is a major barrier to practical use of DNA sequence data. The late Professor Dick Cotton devoted his life to innovation in molecular genetics and was a prime mover in the international response to the need to understand the "variome." His leadership resulted in the launch first of the Human Genetic Variation Society and then, in 2006, an international agreement to launch the Human Variome Project (HVP), aimed at data integration enabled by standards and infrastructure of the databases of variants being identified in families with a range of inherited disorders. The project attracted a network of affiliates across 81 countries and earned formal recognition by UNESCO, which now hosts its biennial meetings. It has also signed a Memorandum of Understanding with the World Health Organization. Future progress will depend on longer term secure funding and integration with the efforts of the genomics community where the rapid advances in sequencing technology have enabled variant capture on a previously unimaginable scale. Efforts are underway to integrate the efforts of HVP with those of the Global Alliance for Genomics and Health to provide a lasting legacy of Dick Cotton's vision. PMID:26987309

  14. The Human Genome Diversity Project

    SciTech Connect

    Cavalli-Sforza, L.

    1994-12-31

    The Human Genome Diversity Project (HGD Project) is an international anthropology project that seeks to study the genetic richness of the entire human species. This kind of genetic information can add a unique thread to the tapestry knowledge of humanity. Culture, environment, history, and other factors are often more important, but humanity`s genetic heritage, when analyzed with recent technology, brings another type of evidence for understanding species` past and present. The Project will deepen the understanding of this genetic richness and show both humanity`s diversity and its deep and underlying unity. The HGD Project is still largely in its planning stages, seeking the best ways to reach its goals. The continuing discussions of the Project, throughout the world, should improve the plans for the Project and their implementation. The Project is as global as humanity itself; its implementation will require the kinds of partnerships among different nations and cultures that make the involvement of UNESCO and other international organizations particularly appropriate. The author will briefly discuss the Project`s history, describe the Project, set out the core principles of the Project, and demonstrate how the Project will help combat the scourge of racism.

  15. The Digital Humanities as a Humanities Project

    ERIC Educational Resources Information Center

    Svensson, Patrik

    2012-01-01

    This article argues that the digital humanities can be seen as a humanities project in a time of significant change in the academy. The background is a number of scholarly, educational and technical challenges, the multiple epistemic traditions linked to the digital humanities, the potential reach of the field across and outside the humanities,…

  16. Virtual Human Project

    SciTech Connect

    Ward, RD

    2001-06-12

    This paper describes the development of a comprehensive human modeling environment, the Virtual Human, which will be used initially to model the human respiratory system for purposes of predicting pulmonary disease or injury using lung sounds. The details of the computational environment, including the development of a Virtual Human Thorax, a database for storing models, model parameters, and experimental data, and a Virtual Human web interface are outlined. Preliminary progress in developing this environment will be presented. A separate paper at the conference describes the modeling of sound generation using computational fluid dynamics and the modeling of sound propagation in the human respiratory system.

  17. Virtual Human project

    NASA Astrophysics Data System (ADS)

    Ward, Richard C.; Kruse, Kara L.; Allgood, Glenn O.; Hively, Lee M.; Fischer, K. N.; Munro, Nancy B.; Easterly, Clay E.

    2001-08-01

    This paper describes the development of a comprehensive human modeling environment, the Virtual Human, which will be used initially to model the human respiratory system for purposes of predicting pulmonary disease or injury using lung sounds. The details of the computational environment, including the development of a Virtual Human Thorax, a database for storing models, model parameters, and experimental data, and a Virtual Human web interface are outlined. Preliminary progress in developing this environment will be presented. A separate paper at the conference describes the modeling of sound generation using computational fluid dynamics and the modeling of sound propagation in the human respiratory system.

  18. All about the Human Genome Project (HGP)

    MedlinePlus

    ... full human sequence All About The Human Genome Project (HGP) The Human Genome Project (HGP) was one of the great feats of ... Organisms A Quarter Century after the Human Genome Project's Launch: Lessons Beyond the Base Pairs October 1, ...

  19. DSN human factors project

    NASA Technical Reports Server (NTRS)

    Chafin, R. L.; Martin, T. H.

    1980-01-01

    The project plan was to hold focus groups to identify the factors influencing the ease of use characteristics of software and to bond the problem. A questionnaire survey was conducted to evaluate those factors which were more appropriately measured with that method. The performance oriented factors were analyzed and relationships hypothesized. The hypotheses were put to test in the experimental phase of the project. In summary, the initial analysis indicates that there is an initial performance effect favoring computer controlled dialogue but the advantage fades fast as operators become experienced. The user documentation style is seen to have a significant effect on performance. The menu and prompt command formats are preferred by inexperienced operators. The short form mnemonic is least favored. There is no clear best command format but the short form mnemonic is clearly the worst.

  20. Ashland Area Support Substation Project

    SciTech Connect

    Not Available

    1992-06-01

    The Bonneville Power Administration (BPA) provides wholesale electric service to the City of Ashland (the City) by transferring power over Pacific Power Light Company's (PP L) 115-kilovolt (kV) transmission lines and through PP L's Ashland and Oak Knoll Substations. The City distributes power over a 12.5-kV system which is heavily loaded during winter peak periods and which has reached the limit of its ability to serve peak loads in a reliable manner. Peak loads under normal winter conditions have exceeded the ratings of the transformers at both the Ashland and Oak Knoll Substations. In 1989, the City modified its distribution system at the request of PP L to allow transfer of three megawatts (MW's) of electric power from the overloaded Ashland Substation to the Oak Knoll Substation. In cooperation with PP L, BPA installed a temporary 6-8 megavolt-amp (MVA) 115-12.5-kV transformer for this purpose. This additional transformer, however, is only a temporary remedy. BPA needs to provide additional, reliable long-term service to the Ashland area through additional transformation in order to keep similar power failures from occurring during upcoming winters in the Ashland area. The temporary installation of another 20-MVA mobile transformer at the Ashland Substation and additional load curtailment are currently being studied to provide for sustained electrical service by the peak winter period 1992. Two overall electrical plans-of-service are described and evaluated in this report. One of them is proposed for action. Within that proposed plan-of-service are location options for the substation. Note that descriptions of actions that may be taken by the City of Ashland are based on information provided by them.

  1. St. Louis Area Earthquake Hazards Mapping Project

    USGS Publications Warehouse

    Williams, Robert A.; Steckel, Phyllis; Schweig, Eugene

    2007-01-01

    St. Louis has experienced minor earthquake damage at least 12 times in the past 200 years. Because of this history and its proximity to known active earthquake zones, the St. Louis Area Earthquake Hazards Mapping Project will produce digital maps that show variability of earthquake hazards in the St. Louis area. The maps will be available free via the internet. They can be customized by the user to show specific areas of interest, such as neighborhoods or transportation routes.

  2. Bridging Disciplines with the Riparian Area Management Project

    ERIC Educational Resources Information Center

    Cockerill, Kristan M.; Titus, Jonathan H.

    2004-01-01

    Faculty at Columbia University's Earth Semester created the interdisciplinary Riparian Area Management Project to help students integrate information and skills from life sciences, geosciences, social sciences, and humanities focused coursework. Structured as a "consulting" contract, students were required to make a policy recommendation utilizing…

  3. CATSKILL AREA PROJECT IN SMALL SCHOOL DESIGN.

    ERIC Educational Resources Information Center

    Catskill Area Project in Small School Design, Oneonta, NY.

    CHARACTERISTICS OF THE SMALL SCHOOL, AS PROPOSED BY THE PROJECT, ARE LISTED. FIVE AREAS OF SCHOOL OPERATION ARE DISCUSSED IN DETAIL--(1) MULTIPLE CLASSES, INCLUDING SUPERVISED CORRESPONDENCE COURSES, (2) FLEXIBLE SCHEDULES, (3) USE OF SCHOOL AIDES, (4) USES OF ELECTRONIC COMMUNICATION, AND (5) SHARED SERVICES AND TALENTED YOUTH. A MAP LOCATING THE…

  4. Projecting global datasets to achieve equal areas

    USGS Publications Warehouse

    Usery, E.L.; Finn, M.P.; Cox, J.D.; Beard, T.; Ruhl, S.; Bearden, M.

    2003-01-01

    Scientists routinely accomplish global modeling in the raster domain, but recent research has indicated that the transformation of large areas through map projection equations leads to errors. This research attempts to gauge the extent of map projection and resampling effects on the tabulation of categorical areas by comparing the results of three datasets for seven common projections. The datasets, Global Land Cover, Holdridge Life Zones, and Global Vegetation, were compiled at resolutions of 30 arc-second, 1/2 degree, and 1 degree, respectively. These datasets were projected globally from spherical coordinates to plane representations. Results indicate significant problems in the implementation of global projection transformations in commercial software, as well as differences in areal accuracy across projections. The level of raster resolution directly affects the accuracy of areal tabulations, with higher resolution yielding higher accuracy. If the raster resolution is high enough for individual pixels to approximate points, the areal error tends to zero. The 30-arc-second cells appear to approximate this condition.

  5. The NIH Human Microbiome Project

    PubMed Central

    Peterson, Jane; Garges, Susan; Giovanni, Maria; McInnes, Pamela; Wang, Lu; Schloss, Jeffery A.; Bonazzi, Vivien; McEwen, Jean E.; Wetterstrand, Kris A.; Deal, Carolyn; Baker, Carl C.; Di Francesco, Valentina; Howcroft, T. Kevin; Karp, Robert W.; Lunsford, R. Dwayne; Wellington, Christopher R.; Belachew, Tsegahiwot; Wright, Michael; Giblin, Christina; David, Hagit; Mills, Melody; Salomon, Rachelle; Mullins, Christopher; Akolkar, Beena; Begg, Lisa; Davis, Cindy; Grandison, Lindsey; Humble, Michael; Khalsa, Jag; Little, A. Roger; Peavy, Hannah; Pontzer, Carol; Portnoy, Matthew; Sayre, Michael H.; Starke-Reed, Pamela; Zakhari, Samir; Read, Jennifer; Watson, Bracie; Guyer, Mark

    2009-01-01

    The Human Microbiome Project (HMP), funded as an initiative of the NIH Roadmap for Biomedical Research (http://nihroadmap.nih.gov), is a multi-component community resource. The goals of the HMP are: (1) to take advantage of new, high-throughput technologies to characterize the human microbiome more fully by studying samples from multiple body sites from each of at least 250 “normal” volunteers; (2) to determine whether there are associations between changes in the microbiome and health/disease by studying several different medical conditions; and (3) to provide both a standardized data resource and new technological approaches to enable such studies to be undertaken broadly in the scientific community. The ethical, legal, and social implications of such research are being systematically studied as well. The ultimate objective of the HMP is to demonstrate that there are opportunities to improve human health through monitoring or manipulation of the human microbiome. The history and implementation of this new program are described here. PMID:19819907

  6. Freihoelser Forst Local Training Area rehabilitation project

    SciTech Connect

    Hinchman, R.R.; Zellmer, S.D.; Johnson, D.O.; Severinghaus, W.D.; Brent, J.J. . Environmental Div.)

    1991-12-01

    Intensive and continued use of the Freihoelser Forst Local Training Area (LTA) for military training activities had resulted in serious environmental problems, exemplified by a lack of vegetative cover and severe erosion by water and wind. The project's goal was to develop and demonstrate rapid, cost-effective methods to stabilize the LTA's barren, eroding maneuver areas and make training conditions more realistic. The major factors limiting rehabilitation efforts were the sandy, infertile, and acidic soils. The project was conducted in two phases. Phase I demonstrated and evaluated three separate rehabilitation treatments ranging in cost from moderate to expensive. Each treatment used a different type of soil amendment (fertilizer and straw, compost, or chicken manure), but all used identical seedbed preparation methods and seed mixtures. Phase I was conducted on relatively small replicated plots and was monitored three times during each growing season. All three treatments satisfactorily reestablished vegetation and controlled erosion. Because of their small size, the Phase I demonstration plots had only a minor stabilizing effect on the erosion problems of the LTA as a whole. The Phase II treatment was based on lessons teamed from Phase I and from other revegetation projects in Germany. Phase II revegetated a large area of the LTA, which included nearly all of the most severely disturbed land. Phase II, which was monitored in the same way as Phase I but for a shorter period of time, was highly successful in stabilizing most areas treated. The revegetation plant community was dominated by native grasses and legumes that stabilized the loose, sandy soils and improved the training realism of a major portion of the LTA.

  7. 78 FR 66695 - Loveland Area Projects, Colorado River Storage Project, Pacific Northwest-Pacific Southwest...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-06

    ... Area Power Administration Loveland Area Projects, Colorado River Storage Project, Pacific Northwest-Pacific Southwest Intertie Project, Central Arizona Project, and Parker-Davis Project--Rate Order No. WAPA... Western Area Power Administration (Western) Transmission Projects to Enter into WestConnect's...

  8. The Human Connectome Project's neuroimaging approach.

    PubMed

    Glasser, Matthew F; Smith, Stephen M; Marcus, Daniel S; Andersson, Jesper L R; Auerbach, Edward J; Behrens, Timothy E J; Coalson, Timothy S; Harms, Michael P; Jenkinson, Mark; Moeller, Steen; Robinson, Emma C; Sotiropoulos, Stamatios N; Xu, Junqian; Yacoub, Essa; Ugurbil, Kamil; Van Essen, David C

    2016-08-26

    Noninvasive human neuroimaging has yielded many discoveries about the brain. Numerous methodological advances have also occurred, though inertia has slowed their adoption. This paper presents an integrated approach to data acquisition, analysis and sharing that builds upon recent advances, particularly from the Human Connectome Project (HCP). The 'HCP-style' paradigm has seven core tenets: (i) collect multimodal imaging data from many subjects; (ii) acquire data at high spatial and temporal resolution; (iii) preprocess data to minimize distortions, blurring and temporal artifacts; (iv) represent data using the natural geometry of cortical and subcortical structures; (v) accurately align corresponding brain areas across subjects and studies; (vi) analyze data using neurobiologically accurate brain parcellations; and (vii) share published data via user-friendly databases. We illustrate the HCP-style paradigm using existing HCP data sets and provide guidance for future research. Widespread adoption of this paradigm should accelerate progress in understanding the brain in health and disease. PMID:27571196

  9. Power Law Mapping in Human Area Perception

    NASA Astrophysics Data System (ADS)

    Longjas, Anthony; Legara, Erika Fille; Monterola, Christopher

    We investigate how humans visually perceive and approximate area or space allocation through visual area experiments. The participants are asked to draw a circle concentric to the reference circle on the monitor screen using a computer mouse with area measurements relative to the area of the reference circle. The activity is repeated for triangle, square and hexagon. The area estimated corresponds to the area estimates of a participant (perceived) for a corresponding requested area to be drawn (stimulus). The area estimated fits very well (goodness of fit R2 > 0.97) to a power law given by r2α where r is the radius of the circle or the distance of the edge for triangle, square and hexagon. The power law fit demonstrates that for all shapes sampled, participants underestimated area for stimulus that are less than ~100% of the reference area and overestimated area for stimulus greater than ~100% of the reference area. The value of α is smallest for the circle (α∘ ≈ 1.33) and largest for triangle (α△ ≈ 1.56) indicating that in the presence of a reference area with the same shape, circle is perceived to be smallest among the figures considered when drawn bigger than the reference area, but largest when drawn smaller than the reference area. We also conducted experiments on length estimation and consistent with the results of Dehaene et al., Science 2008, we recover a linear relationship between the perceived length and the stimulus. We show that contrary to number mapping into space and/or length perception, human's perception of area is not corrected by the introduction of cultural interventions such as formal education.

  10. 7 CFR 1450.201 - Project area proposal submission requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... determined by CCC. (d) Project area proposals may limit the nature and types of eligible crops to be... 7 Agriculture 10 2011-01-01 2011-01-01 false Project area proposal submission requirements. 1450... ASSISTANCE PROGRAM (BCAP) Establishment Payments and Annual Payments § 1450.201 Project area...

  11. 7 CFR 1450.201 - Project area proposal submission requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... determined by CCC. (d) Project area proposals may limit the nature and types of eligible crops to be... 7 Agriculture 10 2013-01-01 2013-01-01 false Project area proposal submission requirements. 1450... ASSISTANCE PROGRAM (BCAP) Establishment Payments and Annual Payments § 1450.201 Project area...

  12. 7 CFR 1450.201 - Project area proposal submission requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... determined by CCC. (d) Project area proposals may limit the nature and types of eligible crops to be... 7 Agriculture 10 2012-01-01 2012-01-01 false Project area proposal submission requirements. 1450... ASSISTANCE PROGRAM (BCAP) Establishment Payments and Annual Payments § 1450.201 Project area...

  13. 7 CFR 1450.201 - Project area proposal submission requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... determined by CCC. (d) Project area proposals may limit the nature and types of eligible crops to be... 7 Agriculture 10 2014-01-01 2014-01-01 false Project area proposal submission requirements. 1450... ASSISTANCE PROGRAM (BCAP) Establishment Payments and Annual Payments § 1450.201 Project area...

  14. Climate Change Projections for African Urban Areas

    NASA Astrophysics Data System (ADS)

    Simonis, Ingo; Engelbrecht, Francois; Bucchignani, Edoardo; Mercogliano, Paola; Naidoo, Mogesh

    2013-04-01

    Mainly driven by changes in the orbital characteristics of Earth around the sun, the planet's climate has been continuously changing over periods of tens of thousands of years. However, the warming that has been detected in the Earth's atmosphere over the last century is occurring at a rate that cannot be explained by any known natural cycle. Main-stream science has indeed reached consensus that the 'enhanced green house effect', caused by the interplay of incoming short-wave irradiation, outgoing long-wave radiation and the absorption of energy by enhanced levels of CO2 and water vapour in the troposphere, is the main forcing mechanism responsible for the phenomena of global warming. The enhanced greenhouse effect strengthens the 'natural green house effect' that results from the CO2 and water vapour occurring naturally in the atmosphere. The continuous burning of fossil fuels since the industrial revolution and the simultaneous degradation of large forests, are the main reasons for the increase in CO2 concentrations in the atmosphere. The availability of climate change projection data varies considerably for different areas on Earth. Whereas the data centres storing climate change projections for Europe and North America now store petabytes of data, regionally downscaled projections for Africa are rarely available. In the context of the research project CLUVA, (Assessing vulnerability of urban systems, populations and goods in relation to natural and man-made disasters in Africa, co-funded by the European Commission under grant agreement no: 265137), the Council for Industrial and Scientific Research (CSIR) in South Africa and the Centro Euro-Mediterraneo sui Cambiamenti Climatici (CMCC) in Italy have produced a large set of projections of climate change over Africa, covering the time period 1950 to 2100. Through the collaboration between CMCC and CSIR, a multi-model ensemble of eight high-resolution simulations of climate change over parts of West and East

  15. 75 FR 48986 - Northwest Area Water Supply Project, North Dakota

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-12

    ... Bureau of Reclamation Northwest Area Water Supply Project, North Dakota AGENCY: Bureau of Reclamation... 1969 (NEPA) on a Supplemental Environmental Impact Statement (EIS) for the Northwest Area Water Supply..., Northwest Area Water Supply Project EIS, Bureau of Reclamation, Dakotas Area Office, P.O. Box 1017,...

  16. Spatial augmented reality based high accuracy human face projection

    NASA Astrophysics Data System (ADS)

    Li, Dong; Xie, Jinghui; Li, Yufeng; Weng, Dongdong; Liu, Yue

    2015-08-01

    This paper discusses the imaging principles and the technical difficulties of spatial augmented reality based human face projection. A novel geometry correction method is proposed to realize fast, high-accuracy face model projection. Using a depth camera to reconstruct the projected object, the relative position from the rendered model to the projector can be accessed and the initial projection image is generated. Then the projected image is distorted by using Bezier interpolation to guarantee that the projected texture matches with the object surface. The proposed method is under a simple process flow and can achieve high perception registration of virtual and real object. In addition, this method has a good performance in the condition that the reconstructed model is not exactly same with the rendered virtual model which extends its application area in the spatial augmented reality based human face projection.

  17. A motion area in human visual cortex.

    PubMed Central

    Orban, G A; Dupont, P; De Bruyn, B; Vogels, R; Vandenberghe, R; Mortelmans, L

    1995-01-01

    We have localized an area in the human brain involved in the processing of contours defined by motion differences (kinetic contours) by comparing with positron emission tomography the regional cerebral blood flow in tasks performed with kinetic and luminance-defined gratings. These tasks included passive viewing, counting the total number of grating stimuli, and counting the number of gratings of a given orientation. Comparison between the counting tasks and passive viewing with a given type of contour revealed a set of active areas that were similar for both luminance-defined and kinetic contours. Comparisons between these two types of contours revealed a single focus in the right hemisphere that did not overlap with the many regions activated by uniform motion. In particular this "kinetic focus" was clearly separated from the area previously defined as the human homologue of V5/middle temporal. Activity in this kinetic focus was stronger when orientation had to be processed than in the other two tasks. These results and control experiments with uniformly moving random dot patterns suggest the existence of an area in the human visual system that is activated much more by kinetic contours than by luminance contours or uniformly moving random dots. Up to now, such an area has not been described in the monkey visual system. Images Fig. 1 Fig. 2 Fig. 4 PMID:7862680

  18. 75 FR 49518 - Northwest Area Water Supply Project, North Dakota

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-13

    ... Bureau of Reclamation Northwest Area Water Supply Project, North Dakota AGENCY: Bureau of Reclamation... 1969 (NEPA) on a Supplemental Environmental Impact Statement (EIS) for the Northwest Area Water Supply... Water Supply Project EIS, Bureau of Reclamation, Dakotas Area Office, P.O. Box 1017, Bismarck, ND...

  19. JSC Human Life Sciences Project

    NASA Technical Reports Server (NTRS)

    1998-01-01

    This section of the Life and Microgravity Spacelab (LMS) publication includes articles entitled: (1) E029 - Magnetic Resonance Imaging after Exposure to Microgravity; (2) E030 - Extended Studies of Pulmonary Function in Weightlessness; (3) E074 - Direct Measurement of the Initial Bone Response to Spaceflight in Humans; (4) E401 - The Effects of Microgravity on Skeletal Muscle Contractile Properties; (5) E407 - Effects of Microgravity on the Biochemical and Bioenergetic Characteristics of Human Skeletal Muscle; (6) E410 - Torso Rotation Experiment; (7) E920 - Effect of Weightlessness on Human Single Muscle Fiber Function; (8) E948 - Human Sleep, Circadian Rhythms and Performance in Space; (9) E963 - Microgravity Effects on Standardized Cognitive Performance Measures; and (10) E971 - Measurement of Energy Expenditures During Spaceflight Using the Doubly Labeled Water Method

  20. Sediment Properties: E-Area Completion Project

    SciTech Connect

    Millings, M.; Bagwell, L.; Amidon, M.; Dixon, K.

    2011-04-29

    To accommodate a future need for additional waste disposal facilities at the Savannah River Site, the Solid Waste Management Division (SWMD) designated nine additional plots for development (Kasraii 2007; SRS 2010); these plots are collectively known as the E Area Completion Project (ECP). Subsurface samples were collected from ECP plots 6, 7, 8 and 9 (Figure 1) for chemical and physical property analyses to support Performance Assessment (PA) and Special Analyses (SA) modeling. This document summarizes the sampling and analysis scheme and the resultant data, and provides interpretations of the data particularly in reference to existing soil property data. Analytical data in this document include: gamma log, cone penetrometer log, grain size (sieve and hydrometer), water retention, saturated hydraulic conductivity (falling head permeameter), porosity, dry bulk density, total organic carbon, x-ray diffraction, and x-ray fluorescence data. SRNL provided technical and safety oversight for the fieldwork, which included completion of eight soil borings, four geophysical logs, and the collection of 522 feet of core and 33 Shelby tubes from ECP plots 6, 7, 8, and 9. Boart Longyear provided sonic drilling and logging services. Two soil borings were completed at each location. The first set of boreholes extended into (but did not fully penetrate) the Warley Hill Formation. These boreholes were continuously cored, then geophysically (gamma ray) logged. The recovered core was split, photographed, and described; one half of the core was archived at SRS's Core Lab facilities, and the remaining half was consumed as necessary for testing at SRS and off-site labs. Core descriptions and geophysical data were used to calculate target elevations for Shelby tube samples, which were obtained from the second set of boreholes. Shelby tubes were shipped to MACTEC Engineering and Consulting Inc. (MACTEC) in Atlanta for physical property testing. SRNL deployed their Site Characterization

  1. Information Presentation: Human Research Program - Space Human Factors and Habitability, Space Human Factors Engineering Project

    NASA Technical Reports Server (NTRS)

    Holden, Kristina L.; Sandor, Aniko; Thompson, Shelby G.; Kaiser, Mary K.; McCann, Robert S.; Begault, D. R.; Adelstein, B. D.; Beutter, B. R.; Wenzel, E. M.; Godfroy, M.; Stone, L. S.

    2010-01-01

    The goal of the Information Presentation Directed Research Project (DRP) is to address design questions related to the presentation of information to the crew. The major areas of work, or subtasks, within this DRP are: 1) Displays, 2) Controls, 3) Electronic Procedures and Fault Management, and 4) Human Performance Modeling. This DRP is a collaborative effort between researchers atJohnson Space Center and Ames Research Center. T

  2. Cortical representation area of human dental pulp.

    PubMed

    Kubo, K; Shibukawa, Y; Shintani, M; Suzuki, T; Ichinohe, T; Kaneko, Y

    2008-04-01

    To elucidate the dental pulp-representing area in the human primary somatosensory cortex and the presence of A-beta fibers in dental pulp, we recorded somatosensory-evoked magnetic fields from the cortex in seven healthy persons using magnetoencephalography. Following non-painful electrical stimulation of the right maxillary first premolar dental pulp, short latency (27 ms) cortical responses on the magnetic waveforms were observed. However, no response was seen when stimulation was applied to pulpless teeth, such as devitalized teeth. The current source generating the early component of the magnetic fields was located anterior-inferiorly compared with the locations for the hand area in the primary somatosensory cortex. These results demonstrate the dental pulp representation area in the primary somatosensory cortex, and that it receives input from intradental A-beta neurons, providing a detailed organizational map of the orofacial area, by adding dental pulp to the classic "sensory homunculus". PMID:18362319

  3. Selecting Map Projections in Minimizing Area Distortions in GIS Applications

    PubMed Central

    Yildirim, Faruk; Kaya, Ahmet

    2008-01-01

    Various software for Geographical Information Systems (GISs) have been developed and used in many different engineering projects. In GIS applications, map coverage is important in terms of performing reliable and meaningful queries. Map projections can be conformal, equal-area and equidistant. The goal of an application plays an important role in choosing one of those projections. Choosing the equal-area projection for an application in which area information is used (forestry, agriculture, ecosystem etc) reduces the amount of distortion on the area, but many users using GIS ignore this fact and continue to use applications with present map sheets no matter in what map projection it is. For example, extracting area information from data whose country system's map sheet is in conformal projection is relatively more distorted, compared to an equal-area projection one. The goal of this study is to make the best decision in choosing the most proper equal-area projection among the choices provided by ArcGIS 9.0, which is a popular GIS software package, and making a comparison on area errors when conformal projection is used. In this study, the area of parcels chosen in three different regions and geographic coordinates and whose sizes vary between 0.01 to 1,000,000 ha are calculated according to Transversal Mercator (TM, 3°), Universal Transversal Mercator (UTM, 6°) and 14 different equal-area projections existing in the ArcGIS 9.0 GIS software package. The parcel areas calculated with geographical coordinates are accepted as definite. The difference between the sizes calculated according to projection coordinates and real sizes of the parcels are determined. Consequently, the appropriate projections are decided for the areas smaller and equal than 1,000 ha and greater than 1,000 ha in the GIS software package.

  4. Attitudes towards the Human Genome Project.

    ERIC Educational Resources Information Center

    Shahroudi, Julie; Shaw, Geraldine

    Attitudes concerning the Human Genome Project were reported by faculty (N=40) and students (N=66) from a liberal arts college. Positive attitudes toward the project involved privacy, insurance and health, economic purposes, reproductive purposes, genetic counseling, religion and overall opinions. Negative attitudes were expressed regarding…

  5. Scientific Goals of the Human Genome Project.

    ERIC Educational Resources Information Center

    Wills, Christopher

    1993-01-01

    The Human Genome Project, an effort to sequence all the DNA of a human cell, is needed to better understand the behavior of chromosomes during cell division, with the ultimate goal of understanding the specific genes contributing to specific diseases and disabilities. (MSE)

  6. The Human Microbiome Project: lessons from human genomics.

    PubMed

    Lewis, Cecil M; Obregón-Tito, Alexandra; Tito, Raul Y; Foster, Morris W; Spicer, Paul G

    2012-01-01

    The Human Microbiome Project (HMP) is following in the footsteps of the Human Genome Project (HGP), which will include exciting discoveries, but also potential disappointment and resentment over the lack of medical applications. There is a wiser path for the HMP. This path includes a greater attention to rare variation, an early commitment to an ethical inclusion of indigenous communities, and a recruitment strategy in which medical benefits are de-emphasized. PMID:22112388

  7. Origins of the human genome project

    SciTech Connect

    Watson, J.D.; Cook-Deegan, R.M. )

    1991-01-01

    The Human Genome Project has become a reality. Several genome projects are now in full stride around the world, and more are likely to form in the next several years. The purpose of genome projects is to assemble data on the structure of DNA in human chromosomes and those of other organisms. A second goal is to develop new technologies to perform mapping and sequencing. There have been impressive technical advances in the past 5 years. We are on the verge of beginning pilot projects to test several approaches to sequencing long stretches of DNA, using both automation and manual methods. Ordered sets of yeast artificial chromosome and cosmid clones have been assembled to span more than 2 million base pairs of several human chromosomes, and a region of 10 million base pairs has been assembled for Caenorhabditis elegans.

  8. Implications of the Human Genome Project

    SciTech Connect

    Kitcher, P.

    1998-11-01

    The Human Genome Project (HGP), launched in 1991, aims to map and sequence the human genome by 2006. During the fifteen-year life of the project, it is projected that $3 billion in federal funds will be allocated to it. The ultimate aims of spending this money are to analyze the structure of human DNA, to identify all human genes, to recognize the functions of those genes, and to prepare for the biology and medicine of the twenty-first century. The following summary examines some of the implications of the program, concentrating on its scientific import and on the ethical and social problems that it raises. Its aim is to expose principles that might be used in applying the information which the HGP will generate. There is no attempt here to translate the principles into detailed proposals for legislation. Arguments and discussion can be found in the full report, but, like this summary, that report does not contain any legislative proposals.

  9. 1970 Project Understanding: A Community Education Project on Human Survival.

    ERIC Educational Resources Information Center

    Wisconsin Univ., Milwaukee.

    The purposes of Project Understanding were to help participants to: obtain accurate information of human survival issues relating to people, poverty, pollution, and politics; think through the implications of these issues and examine their opinions about them; change their own opinions, attitudes, and behavior; and take effective citizen action.…

  10. Estimation of human carrying capacity in rainforest areas.

    PubMed

    Fearnside, P M

    1990-06-01

    Tropical rainiorest areas are rapidly being settled as a result of continued growth of local populations, spontaneous migration from non-rainiorest areas and planned settlement projects undertaken by governments. National decision makers frequently view rainiorest settlement as a solution to the problems of other regions undergoing population growth, land tenure concentration, environmental degradation, agricultural mechanization and population displacement by development projects. Natural habitats are replaced by settlements that often cannot support the density of population expected of them. Inappropriate assumptions can lead to estimates that are orders of magnitude too high, such as an FAO calculation that Brazil could support over seven billion people if Amazonia were converted to intensive agriculture. Inadequate information on human carrying capacity allows planners to foster unrealistic expectations. PMID:21232352

  11. Human genetics: international projects and personalized medicine.

    PubMed

    Apellaniz-Ruiz, Maria; Gallego, Cristina; Ruiz-Pinto, Sara; Carracedo, Angel; Rodríguez-Antona, Cristina

    2016-03-01

    In this article, we present the progress driven by the recent technological advances and new revolutionary massive sequencing technologies in the field of human genetics. We discuss this knowledge in relation with drug response prediction, from the germline genetic variation compiled in the 1000 Genomes Project or in the Genotype-Tissue Expression project, to the phenome-genome archives, the international cancer projects, such as The Cancer Genome Atlas or the International Cancer Genome Consortium, and the epigenetic variation and its influence in gene expression, including the regulation of drug metabolism. This review is based on the lectures presented by the speakers of the Symposium "Human Genetics: International Projects & New Technologies" from the VII Conference of the Spanish Pharmacogenetics and Pharmacogenomics Society, held on the 20th and 21st of April 2015. PMID:26581075

  12. Characterize Human Forward Contamination Project

    NASA Technical Reports Server (NTRS)

    Rucker, Michelle

    2015-01-01

    Let's face it: wherever we go, we will inevitably carry along the little critters that live in and on us. Conventional wisdom has long held that it's unlikely those critters could survive the space environment, but in 2007 microscopic animals called Tardigrades survived exposure to space and in 2008 Cyanobacteria lived for 548 days outside the International Space Station (ISS). But what about the organisms we might reasonably expect a crewed spacecraft to leak or vent? Do we even know what they are? How long might our tiny hitch-hikers survive in close proximity to a warm spacecraft that periodically leaks/vents water or oxygen-and how might they mutate with long-duration exposure? Unlike the Mars rovers that we cleaned once and sent on their way, crew members will provide a constantly regenerating contaminant source. Are we prepared to certify that we can meet forward contamination protocols as we search for life at new destinations? This project has four technical objectives: 1. TEST: Develop a test plan to leverage existing equipment (i.e. ISS) to characterize the kinds of organisms we can reasonably expect pressurized, crewed volumes to vent or leak overboard; as part of testing, we'll need to develop an Extravehicular Activity (EVA)-compatible tool that can withstand the pressure and temperature extremes of space, as well as collect, separate, and store multiple samples; 2. ANALYSIS: Develop an analysis plan to study those organisms in relevant destination environments, including spacecraft-induced conditions; 3. MODEL: Develop a modeling plan to model organism transport mechanisms in relevant destination environments; 4. SHARE: Develop a plan to disseminate findings and integrate recommendations into exploration requirements & ops. In short, we propose a system engineering approach to roadmap the necessary experiments, analysis, and modeling up front--rather than try to knit together disparate chunks of data into a sensible conclusion after the fact.

  13. Characterize Human Forward Contamination Project

    NASA Technical Reports Server (NTRS)

    Rucker, Michelle

    2015-01-01

    Let's face it: wherever we go, we will inevitably carry along the little critters that live in and on us. Conventional wisdom has long held that it's unlikely those critters could survive the space environment, but in 2007 microscopic animals called Tardigrades survived exposure to space and in 2008 Cyanobacteria lived for 548 days outside the International Space Station (ISS). But what about the organisms we might reasonably expect a crewed spacecraft to leak or vent? Do we even know what they are? How long might our tiny hitch-hikers survive in close proximity to a warm spacecraft that periodically leaks/vents water or oxygen-and how might they mutate with long-duration exposure? Unlike the Mars rovers that we cleaned once and sent on their way, crew members will provide a constantly regenerating contaminant source. Are we prepared to certify that we can meet forward contamination protocols as we search for life at new destinations? This project has four technical objectives: 1. TEST: Develop a test plan to leverage existing equipment (i.e. ISS) to characterize the kinds of organisms we can reasonably expect pressurized, crewed volumes to vent or leak overboard; 2. ANALYSIS: Develop an analysis plan to study those organisms in relevant destination environments, including spacecraft-induced conditions; 3. MODEL: Develop a modeling plan to model organism transport mechanisms in relevant destination environments; 4. SHARE: Develop a plan to disseminate findings and integrate recommendations into exploration requirements & ops. In short, we propose a system engineering approach to roadmap the necessary experiments, analysis, and modeling up front--rather than try to knit together disparate chunks of data into a sensible conclusion after the fact.

  14. Daedalus Project's Light Eagle - Human powered aircraft

    NASA Technical Reports Server (NTRS)

    1987-01-01

    The Michelob Light Eagle is seen here in flight over Rogers Dry Lake at the NASA Dryden Flight Research Center, Edwards, California. The Light Eagle and Daedalus human powered aircraft were testbeds for flight research conducted at Dryden between January 1987 and March 1988. These unique aircraft were designed and constructed by a group of students, professors, and alumni of the Massachusetts Institute of Technology within the context of the Daedalus project. The construction of the Light Eagle and Daedalus aircraft was funded primarily by the Anheuser Busch and United Technologies Corporations, respectively, with additional support from the Smithsonian Air and Space Museum, MIT, and a number of other sponsors. To celebrate the Greek myth of Daedalus, the man who constructed wings of wax and feathers to escape King Minos, the Daedalus project began with the goal of designing, building and testing a human-powered aircraft that could fly the mythical distance, 115 km. To achieve this goal, three aircraft were constructed. The Light Eagle was the prototype aircraft, weighing 92 pounds. On January 22, 1987, it set a closed course distance record of 59 km, which still stands. Also in January of 1987, the Light Eagle was powered by Lois McCallin to set the straight distance, the distance around a closed circuit, and the duration world records for the female division in human powered vehicles. Following this success, two more aircraft were built, the Daedalus 87 and Daedalus 88. Each aircraft weighed approximately 69 pounds. The Daedalus 88 aircraft was the ship that flew the 199 km from the Iraklion Air Force Base on Crete in the Mediterranean Sea, to the island of Santorini in 3 hours, 54 minutes. In the process, the aircraft set new records in distance and endurance for a human powered aircraft. The specific areas of flight research conducted at Dryden included characterizing the rigid body and flexible dynamics of the Light Eagle, investigating sensors for an

  15. Space Human Factors Engineering Gap Analysis Project Final Report

    NASA Technical Reports Server (NTRS)

    Hudy, Cynthia; Woolford, Barbara

    2006-01-01

    Humans perform critical functions throughout each phase of every space mission, beginning with the mission concept and continuing to post-mission analysis (Life Sciences Division, 1996). Space missions present humans with many challenges - the microgravity environment, relative isolation, and inherent dangers of the mission all present unique issues. As mission duration and distance from Earth increases, in-flight crew autonomy will increase along with increased complexity. As efforts for exploring the moon and Mars advance, there is a need for space human factors research and technology development to play a significant role in both on-orbit human-system interaction, as well as the development of mission requirements and needs before and after the mission. As part of the Space Human Factors Engineering (SHFE) Project within the Human Research Program (HRP), a six-month Gap Analysis Project (GAP) was funded to identify any human factors research gaps or knowledge needs. The overall aim of the project was to review the current state of human factors topic areas and requirements to determine what data, processes, or tools are needed to aid in the planning and development of future exploration missions, and also to prioritize proposals for future research and technology development.

  16. Ashland Area Support Substation Project : Environmental Assessment.

    SciTech Connect

    United States. Bonneville Power Administration.

    1992-06-01

    The Bonneville Power Administration (BPA) provides wholesale electric service to the City of Ashland (the City) by transferring power over Pacific Power & Light Company`s (PP&L) 115-kilovolt (kV) transmission lines and through PP&L`s Ashland and Oak Knoll Substations. The City distributes power over a 12.5-kV system which is heavily loaded during winter peak periods and which has reached the limit of its ability to serve peak loads in a reliable manner. Peak loads under normal winter conditions have exceeded the ratings of the transformers at both the Ashland and Oak Knoll Substations. In 1989, the City modified its distribution system at the request of PP&L to allow transfer of three megawatts (MW`s) of electric power from the overloaded Ashland Substation to the Oak Knoll Substation. In cooperation with PP&L, BPA installed a temporary 6-8 megavolt-amp (MVA) 115-12.5-kV transformer for this purpose. This additional transformer, however, is only a temporary remedy. BPA needs to provide additional, reliable long-term service to the Ashland area through additional transformation in order to keep similar power failures from occurring during upcoming winters in the Ashland area. The temporary installation of another 20-MVA mobile transformer at the Ashland Substation and additional load curtailment are currently being studied to provide for sustained electrical service by the peak winter period 1992. Two overall electrical plans-of-service are described and evaluated in this report. One of them is proposed for action. Within that proposed plan-of-service are location options for the substation. Note that descriptions of actions that may be taken by the City of Ashland are based on information provided by them.

  17. The Human Genome Project and Biology Education.

    ERIC Educational Resources Information Center

    McInerney, Joseph D.

    1996-01-01

    Highlights the importance of the Human Genome Project in educating the public about genetics. Discusses four challenges that science educators must address: teaching for conceptual understanding, the nature of science, the personal and social impact of science and technology, and the principles of technology. Contains 45 references. (JRH)

  18. Think Big! The Human Condition Project

    ERIC Educational Resources Information Center

    Metcalfe, Gareth

    2014-01-01

    How can educators provide children with a genuine experience of carrying out an extended scientific investigation? And can teachers change the perception of what it means to be a scientist? These were key questions that lay behind "The Human Condition" project, an initiative funded by the Primary Science Teaching Trust to explore a new…

  19. Space Mission Human Reliability Analysis (HRA) Project

    NASA Technical Reports Server (NTRS)

    Boyer, Roger

    2014-01-01

    The purpose of the Space Mission Human Reliability Analysis (HRA) Project is to extend current ground-based HRA risk prediction techniques to a long-duration, space-based tool. Ground-based HRA methodology has been shown to be a reasonable tool for short-duration space missions, such as Space Shuttle and lunar fly-bys. However, longer-duration deep-space missions, such as asteroid and Mars missions, will require the crew to be in space for as long as 400 to 900 day missions with periods of extended autonomy and self-sufficiency. Current indications show higher risk due to fatigue, physiological effects due to extended low gravity environments, and others, may impact HRA predictions. For this project, Safety & Mission Assurance (S&MA) will work with Human Health & Performance (HH&P) to establish what is currently used to assess human reliabiilty for human space programs, identify human performance factors that may be sensitive to long duration space flight, collect available historical data, and update current tools to account for performance shaping factors believed to be important to such missions. This effort will also contribute data to the Human Performance Data Repository and influence the Space Human Factors Engineering research risks and gaps (part of the HRP Program). An accurate risk predictor mitigates Loss of Crew (LOC) and Loss of Mission (LOM).The end result will be an updated HRA model that can effectively predict risk on long-duration missions.

  20. The Human Genome Project and eugenic concerns

    SciTech Connect

    Garver, K.L.; Garver, B. )

    1994-01-01

    The US Human Genome Project is the largest scientific project funded by the federal government since the Apollo Moon Project. The overall effect from this project should be of great benefit to humankind because it will provide a better understanding both of single gene defects and multifactorial or familial diseases such as diabetes, arteriosclerosis, and cancer. At first this will lead to more exact ways of screening and diagnosing genetic disease, and later it will lead, in many if not most instances, to specific genetic cures. However, in the past, in both the US and German eugenic movements genetic information has been misused. Hopefully, by remembering and understanding the past injustices and inhumanity of negative eugenics, further misuse of scientific information can be avoided. 142 refs.

  1. The Human Genome Project and eugenic concerns.

    PubMed

    Garver, K L; Garver, B

    1994-01-01

    The U.S. Human Genome project is the largest scientific project funded by the federal government since the Apollo Moon Project. The overall effect from this project should be of great benefit to humankind because it will provide a better understanding both of single gene defects and multifactorial or familial diseases such as diabetes, arteriosclerosis, and cancer. At first this will lead to more exact ways of screening and diagnosing genetic disease, and later it will lead, in many if not most instances, to specific genetic cures. However, in the past, in both the U.S. and German eugenic movements genetic information has been misused. Hopefully, by remembering and understanding the past injustices and inhumanity of negative eugenics, further misuse of scientific information can be avoided. PMID:8279465

  2. 7 CFR 1450.202 - Project area selection criteria.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM... grown on contract acres; (3) The anticipated economic impact in the proposed project area; (4) The... practices, and monoculture and polyculture crop mixes; (8) The range of eligible crops among project...

  3. Proteogenomics Dashboard for the Human Proteome Project.

    PubMed

    Tabas-Madrid, Daniel; Alves-Cruzeiro, Joao; Segura, Victor; Guruceaga, Elizabeth; Vialas, Vital; Prieto, Gorka; García, Carlos; Corrales, Fernando J; Albar, Juan Pablo; Pascual-Montano, Alberto

    2015-09-01

    dasHPPboard is a novel proteomics-based dashboard that collects and reports the experiments produced by the Spanish Human Proteome Project consortium (SpHPP) and aims to help HPP to map the entire human proteome. We have followed the strategy of analog genomics projects like the Encyclopedia of DNA Elements (ENCODE), which provides a vast amount of data on human cell lines experiments. The dashboard includes results of shotgun and selected reaction monitoring proteomics experiments, post-translational modifications information, as well as proteogenomics studies. We have also processed the transcriptomics data from the ENCODE and Human Body Map (HBM) projects for the identification of specific gene expression patterns in different cell lines and tissues, taking special interest in those genes having little proteomic evidence available (missing proteins). Peptide databases have been built using single nucleotide variants and novel junctions derived from RNA-Seq data that can be used in search engines for sample-specific protein identifications on the same cell lines or tissues. The dasHPPboard has been designed as a tool that can be used to share and visualize a combination of proteomic and transcriptomic data, providing at the same time easy access to resources for proteogenomics analyses. The dasHPPboard can be freely accessed at: http://sphppdashboard.cnb.csic.es. PMID:26144527

  4. First concept for a tropical area monitoring project

    NASA Technical Reports Server (NTRS)

    1976-01-01

    The first concept of a tropical area monitoring project is presented. The project would develop an operational system capable of monitoring land areas by machine processing of satellite data. LANDSAT images would be processed within a controlled isolable unit to detect changes in forest cover, rangeland, soil integrity, and other factors important to conservation of tropical ecology. An introductory developmental effort is described to demonstrate the use of LANDSAT data in this application. The independent unit, which functions as a user organization within the development project, assures that the technology will be transferable to a user organization through well defined, easily monitored interfaces with the rest of the world.

  5. Human-Robot Interaction Directed Research Project

    NASA Technical Reports Server (NTRS)

    Rochlis, Jennifer; Ezer, Neta; Sandor, Aniko

    2011-01-01

    Human-robot interaction (HRI) is about understanding and shaping the interactions between humans and robots (Goodrich & Schultz, 2007). It is important to evaluate how the design of interfaces and command modalities affect the human s ability to perform tasks accurately, efficiently, and effectively (Crandall, Goodrich, Olsen Jr., & Nielsen, 2005) It is also critical to evaluate the effects of human-robot interfaces and command modalities on operator mental workload (Sheridan, 1992) and situation awareness (Endsley, Bolt , & Jones, 2003). By understanding the effects of interface design on human performance, workload, and situation awareness, interfaces can be developed that support the human in performing tasks with minimal errors and with appropriate interaction time and effort. Thus, the results of research on human-robot interfaces have direct implications for design. Because the factors associated with interfaces and command modalities in HRI are too numerous to address in 3 years of research, the proposed research concentrates on three manageable areas applicable to National Aeronautics and Space Administration (NASA) robot systems. These topic areas emerged from the Fiscal Year (FY) 2011 work that included extensive literature reviews and observations of NASA systems. The three topic areas are: 1) video overlays, 2) camera views, and 3) command modalities. Each area is described in detail below, along with relevance to existing NASA human-robot systems. In addition to studies in these three topic areas, a workshop is proposed for FY12. The workshop will bring together experts in human-robot interaction and robotics to discuss the state of the practice as applicable to research in space robotics. Studies proposed in the area of video overlays consider two factors in the implementation of augmented reality (AR) for operator displays during teleoperation. The first of these factors is the type of navigational guidance provided by AR symbology. In the proposed

  6. ADP Analysis project for the Human Resources Management Division

    NASA Technical Reports Server (NTRS)

    Tureman, Robert L., Jr.

    1993-01-01

    The ADP (Automated Data Processing) Analysis Project was conducted for the Human Resources Management Division (HRMD) of NASA's Langley Research Center. The three major areas of work in the project were computer support, automated inventory analysis, and an ADP study for the Division. The goal of the computer support work was to determine automation needs of Division personnel and help them solve computing problems. The goal of automated inventory analysis was to find a way to analyze installed software and usage on a Macintosh. Finally, the ADP functional systems study for the Division was designed to assess future HRMD needs concerning ADP organization and activities.

  7. National Writing Project Report. Evaluation of the Bay Area Writing Project. Technical Report.

    ERIC Educational Resources Information Center

    Stahlecker, James; And Others

    Prepared as part of the evaluation of the Bay Area Writing Project (BAWP), this report examines the National Writing Project (NWP) network, a group of teacher training projects designed to replicate the core model of the BAWP. The information provided in this report is divided into three sections. The first section summarizes information regarding…

  8. Projections of leaf area index in earth system models

    NASA Astrophysics Data System (ADS)

    Mahowald, Natalie; Lo, Fiona; Zheng, Yun; Harrison, Laura; Funk, Chris; Lombardozzi, Danica; Goodale, Christine

    2016-03-01

    The area of leaves in the plant canopy, measured as leaf area index (LAI), modulates key land-atmosphere interactions, including the exchange of energy, moisture, carbon dioxide (CO2), and other trace gases and aerosols, and is therefore an essential variable in predicting terrestrial carbon, water, and energy fluxes. Here our goal is to characterize the LAI projections from the latest generation of earth system models (ESMs) for the Representative Concentration Pathway (RCP) 8.5 and RCP4.5 scenarios. On average, the models project increases in LAI in both RCP8.5 and RCP4.5 over most of the globe, but also show decreases in some parts of the tropics. Because of projected increases in variability, there are also more frequent periods of low LAI across broad regions of the tropics. Projections of LAI changes varied greatly among models: some models project very modest changes, while others project large changes, usually increases. Modeled LAI typically increases with modeled warming in the high latitudes, but often decreases with increasing local warming in the tropics. The models with the most skill in simulating current LAI in the tropics relative to satellite observations tend to project smaller increases in LAI in the tropics in the future compared to the average of all the models. Using LAI projections to identify regions that may be vulnerable to climate change presents a slightly different picture than using precipitation projections, suggesting LAI may be an additional useful tool for understanding climate change impacts. Going forward, users of LAI projections from the CMIP5 ESMs evaluated here should be aware that model outputs do not exhibit clear-cut relationships to vegetation carbon and precipitation. Our findings underscore the need for more attention to LAI projections, in terms of understanding the drivers of projected changes and improvements to model skill.

  9. Projections of leaf area index in earth system models

    DOE PAGESBeta

    Mahowald, Natalie; Lo, Fiona; Zheng, Yun; Harrison, Laura; Funk, Chris; Lombardozzi, Danica; Goodale, Christine

    2016-03-09

    The area of leaves in the plant canopy, measured as leaf area index (LAI), modulates key land–atmosphere interactions, including the exchange of energy, moisture, carbon dioxide (CO2), and other trace gases and aerosols, and is therefore an essential variable in predicting terrestrial carbon, water, and energy fluxes. Here our goal is to characterize the LAI projections from the latest generation of earth system models (ESMs) for the Representative Concentration Pathway (RCP) 8.5 and RCP4.5 scenarios. On average, the models project increases in LAI in both RCP8.5 and RCP4.5 over most of the globe, but also show decreases in some partsmore » of the tropics. Because of projected increases in variability, there are also more frequent periods of low LAI across broad regions of the tropics. Projections of LAI changes varied greatly among models: some models project very modest changes, while others project large changes, usually increases. Modeled LAI typically increases with modeled warming in the high latitudes, but often decreases with increasing local warming in the tropics. The models with the most skill in simulating current LAI in the tropics relative to satellite observations tend to project smaller increases in LAI in the tropics in the future compared to the average of all the models. Using LAI projections to identify regions that may be vulnerable to climate change presents a slightly different picture than using precipitation projections, suggesting LAI may be an additional useful tool for understanding climate change impacts. Going forward, users of LAI projections from the CMIP5 ESMs evaluated here should be aware that model outputs do not exhibit clear-cut relationships to vegetation carbon and precipitation. Lastly, our findings underscore the need for more attention to LAI projections, in terms of understanding the drivers of projected changes and improvements to model skill.« less

  10. Projections of leaf area index in earth system models

    SciTech Connect

    Mahowald, Natalie; Lo, Fiona; Zheng, Yun; Harrison, Laura; Funk, Chris; Lombardozzi, Danica; Goodale, Christine

    2016-01-01

    The area of leaves in the plant canopy, measured as leaf area index (LAI), modulates key land–atmosphere interactions, including the exchange of energy, moisture, carbon dioxide (CO2), and other trace gases and aerosols, and is therefore an essential variable in predicting terrestrial carbon, water, and energy fluxes. Here our goal is to characterize the LAI projections from the latest generation of earth system models (ESMs) for the Representative Concentration Pathway (RCP) 8.5 and RCP4.5 scenarios. On average, the models project increases in LAI in both RCP8.5 and RCP4.5 over most of the globe, but also show decreases in some parts of the tropics. Because of projected increases in variability, there are also more frequent periods of low LAI across broad regions of the tropics. Projections of LAI changes varied greatly among models: some models project very modest changes, while others project large changes, usually increases. Modeled LAI typically increases with modeled warming in the high latitudes, but often decreases with increasing local warming in the tropics. The models with the most skill in simulating current LAI in the tropics relative to satellite observations tend to project smaller increases in LAI in the tropics in the future compared to the average of all the models. Using LAI projections to identify regions that may be vulnerable to climate change presents a slightly different picture than using precipitation projections, suggesting LAI may be an additional useful tool for understanding climate change impacts. Going forward, users of LAI projections from the CMIP5 ESMs evaluated here should be aware that model outputs do not exhibit clear-cut relationships to vegetation carbon and precipitation. Our findings underscore the need for more attention to LAI projections, in terms of understanding the drivers of projected changes and improvements to model skill.

  11. Fluid management plan for the Project Shoal Area Offsites Subproject

    SciTech Connect

    1996-08-01

    The US Department of Energy, Nevada Operations Office (DOE/NV) has initiated the Offsites Subproject to characterize the hazards posed to human health and the environment as a result of underground nuclear testing activities at facilities other than the Nevada Test Site (NTS). A primary Subproject objective is to gather adequate data to characterize the various Subproject sites through the collection of surface and subsurface soil samples and by drilling several wells for the collection of groundwater data. The Project Shoal Area (PSA) is one of the Subproject`s Nevada sites and is subject to the requirements set forth in the Federal Facility Compliance Agreement and Consent Order (FFACO) (DOE, 1996a). In accordance with the FFACO, a Corrective Action Investigation Plan (CAIP) has been developed for work at the PSA (designated as Corrective Action Unit Number 416). This Fluid Management Plan (FMP) provides guidance for the management of fluids generated from wells constructed at the PSA. Long-term monitoring and future activities at the site, if required, will be set forth in additional documents as required by the FFACO. The ultimate method for disposition of fluids generated by site operations depends upon sample analysis and process knowledge in relation to fluid management criteria. Section 2 describes well site operations; Section 3 discusses fluid management criteria; Section 4 includes the fluid monitoring program; Section 5 presents the fluid management strategy; Section 6 provides for fluid management during routine well monitoring; and Section 7 contains reporting criteria.

  12. Human Factors Considerations for Area Navigation Departure and Arrival Procedures

    NASA Technical Reports Server (NTRS)

    Barhydt, Richard; Adams, Catherine A.

    2006-01-01

    Area navigation (RNAV) procedures are being implemented in the United States and around the world as part of a transition to a performance-based navigation system. These procedures are providing significant benefits and have also caused some human factors issues to emerge. Under sponsorship from the Federal Aviation Administration (FAA), the National Aeronautics and Space Administration (NASA) has undertaken a project to document RNAV-related human factors issues and propose areas for further consideration. The component focusing on RNAV Departure and Arrival Procedures involved discussions with expert users, a literature review, and a focused review of the NASA Aviation Safety Reporting System (ASRS) database. Issues were found to include aspects of air traffic control and airline procedures, aircraft systems, and procedure design. Major findings suggest the need for specific instrument procedure design guidelines that consider the effects of human performance. Ongoing industry and government activities to address air-ground communication terminology, design improvements, and chart-database commonality are strongly encouraged. A review of factors contributing to RNAV in-service errors would likely lead to improved system design and operational performance.

  13. An overview of the human genome project

    SciTech Connect

    Batzer, M.A.

    1994-01-01

    The human genome project is one of the most ambitious scientific projects to date, with the ultimate goal being a nucleotide sequence for all four billion bases of human DNA. In the process of determining the nucleotide sequence for each base, the location, function, and regulatory regions from the estimated 100,000 human genes will be identified. The genome project itself relies upon maps of the human genetic code derived from several different levels of resolution. Genetic linkage analysis provides a low resolution genome map. The information for genetic linkage maps is derived from the analysis of chromosome specific markers such as Sequence Tagged Sites (STSs), Variable Number of Tandem Repeats (VNTRs) or other polymorphic (highly informative) loci in a number of different-families. Using this information the location of an unknown disease gene can be limited to a region comprised of one million base pairs of DNA or less. After this point, one must construct or have access to a physical map of the region of interest. Physical mapping involves the construction of an ordered overlapping (contiguous) set of recombinant DNA clones. These clones may be derived from a number of different vectors including cosmids, Bacterial Artificial Chromosomes (BACs), P1 derived Artificial Chromosomes (PACs), somatic cell hybrids, or Yeast Artificial Chromosomes (YACs). The ultimate goal for physical mapping is to establish a completely overlapping (contiguous) set of clones for the entire genome. After a gene or region of interest has been localized using physical mapping the nucleotide sequence is determined. The overlap between genetic mapping, physical mapping and DNA sequencing has proven to be a powerful tool for the isolation of disease genes through positional cloning.

  14. Connecting the Human Variome Project to nutrigenomics

    PubMed Central

    Evelo, Chris T.; Perozzi, Giuditta; van Ommen, Ben; Cotton, Richard

    2010-01-01

    Nutrigenomics is the science of analyzing and understanding gene–nutrient interactions, which because of the genetic heterogeneity, varying degrees of interaction among gene products, and the environmental diversity is a complex science. Although much knowledge of human diversity has been accumulated, estimates suggest that ~90% of genetic variation has not yet been characterized. Identification of the DNA sequence variants that contribute to nutrition-related disease risk is essential for developing a better understanding of the complex causes of disease in humans, including nutrition-related disease. The Human Variome Project (HVP; http://www.humanvariomeproject.org/) is an international effort to systematically identify genes, their mutations, and their variants associated with phenotypic variability and indications of human disease or phenotype. Since nutrigenomic research uses genetic information in the design and analysis of experiments, the HVP is an essential collaborator for ongoing studies of gene–nutrient interactions. With the advent of next generation sequencing methodologies and the understanding of the undiscovered variation in human genomes, the nutrigenomic community will be generating novel sequence data and results. The guidelines and practices of the HVP can guide and harmonize these efforts.

  15. Project ATHENA Creates Surrogate Human Organ Systems

    SciTech Connect

    MacQueen, Luke; Knospel, Fanny; Sherrod, Stacy; Iyer, Rashi

    2015-06-15

    The development of miniature surrogate human organs, coupled with highly sensitive mass spectrometry technologies, could one day revolutionize the way new drugs and toxic agents are studied. “By developing this ‘homo minutus,’ we are stepping beyond the need for animal or Petri dish testing: There are huge benefits in developing drug and toxicity analysis systems that can mimic the response of actual human organs,” said Rashi Iyer, a senior scientist at Los Alamos National Laboratory. ATHENA, the Advanced Tissue-engineered Human Ectypal Network Analyzer project team, is nearing the full integration of four human organ constructs — liver, heart, lung and kidney — each organ component is about the size of a smartphone screen, and the whole ATHENA “body” of interconnected organs will fit neatly on a desk. A new video available on the Los Alamos National Laboratory YouTube channel updates the ATHENA project as it begins to integrate the various organ systems into a single system (link to video here). Some 40 percent of pharmaceuticals fail their clinical trials and there are thousands of chemicals whose effects on humans are simply unknown. Providing a realistic, cost-effective and rapid screening system such as ATHENA with high-throughput capabilities could provide major benefits to the medical field, screening more accurately and offering a greater chance of clinical trial success. ATHENA is funded by the Defense Threat Reduction Agency (DTRA) and is a collaboration of Los Alamos National Laboratory, Harvard University, Vanderbilt University, Charité Universitätsmedizin, Berlin, Germany, CFD Research Corporation, and the University of California San Francisco.

  16. Origins of the Human Genome Project

    DOE R&D Accomplishments Database

    Cook-Deegan, Robert (Affiliation: Institute of Medicine, National Academy of Sciences)

    1993-07-01

    The human genome project was borne of technology, grew into a science bureaucracy in the United States and throughout the world, and is now being transformed into a hybrid academic and commercial enterprise. The next phase of the project promises to veer more sharply toward commercial application, harnessing both the technical prowess of molecular biology and the rapidly growing body of knowledge about DNA structure to the pursuit of practical benefits. Faith that the systematic analysis of DNA structure will prove to be a powerful research tool underlies the rationale behind the genome project. The notion that most genetic information is embedded in the sequence of CNA base pairs comprising chromosomes is a central tenet. A rough analogy is to liken an organism's genetic code to computer code. The coal of the genome project, in this parlance, is to identify and catalog 75,000 or more files (genes) in the software that directs construction of a self-modifying and self-replicating system -- a living organism.

  17. Origins of the Human Genome Project

    SciTech Connect

    Cook-Deegan, Robert

    1993-07-01

    The human genome project was borne of technology, grew into a science bureaucracy in the US and throughout the world, and is now being transformed into a hybrid academic and commercial enterprise. The next phase of the project promises to veer more sharply toward commercial application, harnessing both the technical prowess of molecular biology and the rapidly growing body of knowledge about DNA structure to the pursuit of practical benefits. Faith that the systematic analysis of DNA structure will prove to be a powerful research tool underlies the rationale behind the genome project. The notion that most genetic information is embedded in the sequence of CNA base pairs comprising chromosomes is a central tenet. A rough analogy is to liken an organism's genetic code to computer code. The coal of the genome project, in this parlance, is to identify and catalog 75,000 or more files (genes) in the software that directs construction of a self-modifying and self-replicating system -- a living organism.

  18. The Human Brain Project and neuromorphic computing

    PubMed Central

    Calimera, Andrea; Macii, Enrico; Poncino, Massimo

    Summary Understanding how the brain manages billions of processing units connected via kilometers of fibers and trillions of synapses, while consuming a few tens of Watts could provide the key to a completely new category of hardware (neuromorphic computing systems). In order to achieve this, a paradigm shift for computing as a whole is needed, which will see it moving away from current “bit precise” computing models and towards new techniques that exploit the stochastic behavior of simple, reliable, very fast, low-power computing devices embedded in intensely recursive architectures. In this paper we summarize how these objectives will be pursued in the Human Brain Project. PMID:24139655

  19. Privacy and the Human Genome Project.

    PubMed

    Wiesenthal, David L; Wiener, Neil I

    1996-01-01

    The Human Genome Project has raised many issues regarding the contributions of genetics to a variety of diseases and societal conditions. With genetic testing now easily conducted with lowered costs in nonmedical domains, a variety of privacy issues must be considered. Such testing will result in the loss of significant privacy rights for the individual. Society must now consider such issues as the ownership of genetic data, confidentiality rights to such information, limits placed on genetic screening, and legislation to control genetic testing and its applications. There is often a conflict between individual rights to privacy and the need for societal protection. PMID:11654975

  20. The Genome Project and human health

    SciTech Connect

    Collins, F.S. )

    1991-01-01

    The author claims that the positional cloning approach, whereby a gene is identified by its map position without making assumptions about its structure or function, has provided significant information about common inherited disorders. Genes responsible for cystic fibrosis, Duchenne muscular dystrophy, and neurofibromatosis have been cloned. However, this technology has been labor intensive and extremely expensive. The Human Genome Project will provide information that will drive research for at least the next 100 years and will likely transform medicine in the 21st century into the preventive mode.

  1. Justice and the Human Genome Project

    SciTech Connect

    Murphy, T.F.; Lappe, M.

    1992-12-31

    Most of the essays gathered in this volume were first presented at a conference, Justice and the Human Genome, in Chicago in early November, 1991. The goal of the, conference was to consider questions of justice as they are and will be raised by the Human Genome Project. To achieve its goal of identifying and elucidating the challenges of justice inherent in genomic research and its social applications the conference drew together in one forum members from academia, medicine, and industry with interests divergent as rate-setting for insurance, the care of newborns, and the history of ethics. The essays in this volume address a number of theoretical and practical concerns relative to the meaning of genomic research.

  2. Justice and the Human Genome Project

    SciTech Connect

    Murphy, T.F.; Lappe, M.

    1992-01-01

    Most of the essays gathered in this volume were first presented at a conference, Justice and the Human Genome, in Chicago in early November, 1991. The goal of the, conference was to consider questions of justice as they are and will be raised by the Human Genome Project. To achieve its goal of identifying and elucidating the challenges of justice inherent in genomic research and its social applications the conference drew together in one forum members from academia, medicine, and industry with interests divergent as rate-setting for insurance, the care of newborns, and the history of ethics. The essays in this volume address a number of theoretical and practical concerns relative to the meaning of genomic research.

  3. The human genome project and international health

    SciTech Connect

    Watson, J.D.; Cook-Deegan, R.M. )

    1990-06-27

    The human genome project is designed to provide common resources for the study of human genetics, and to assist biomedical researchers in their assault on disease. The main benefit will be to provide several kinds of maps of the human genome, and those of other organisms, to permit rapid isolation of genes for further study about DNA structure and function. This article describes genome research programs in developed and developing countries, and the international efforts that have contributed to genome research programs. For example, the large-scale collaborations to study Duchenne's muscular dystrophy, Huntington's disease, Alzheimer's disease, cystic fibrosis involve collaborators from many nations and families spread throughout the world. In the USA, the US Department of Energy was first to start a dedicated genome research program in 1987. Since then, another major government program has begun at the National Center for Human Genome Research of the National Institutes of Health. Italy, China, Australia, France, Canada, and Japan have genome research programs also.

  4. HIGH SCHOOL PHYSICS BY TELEVISION--THE HOUSTON AREA PROJECT.

    ERIC Educational Resources Information Center

    STREVELL, WALLACE H.

    THE EFFECTIVENESS OF TELEVISION TEACHING WAS INVESTIGATED UNDER VARIED CONDITIONS OF SCHOOL ORGANIZATION SUCH AS URBAN-RURAL, SEGREGATED SCHOOLS, AND HOMOGENEOUS GROUPING. ADDITIONAL OBJECTIVES OF THE PROJECT WERE TO (1) INTRODUCE TEACHING BY OPEN-CIRCUIT TELEVISION AMONG INDEPENDENT SCHOOL DISTRICTS IN THE HOUSTON AREA, (2) DEVELOP PRACTICAL…

  5. Foreign Language/Area Studies Enhancement Project. Final Report.

    ERIC Educational Resources Information Center

    Felker, William; Fuller, Clark

    The Foreign Language/Area Studies Enhancement Program at Central State University (Ohio) is an experience-centered work and study program in Africa designed to give students training in language, culture, and technology. It parallels and supports the university's northern Senegal water management project designed to promote self-sufficiency among…

  6. Overview to northwest of entire project area, from the communications ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Overview to northwest of entire project area, from the communications tower. At farthest left is warehouse A-141. Warehouse A-199 and magazine A-210 are just left of center, and the fresh water tanks are in the right distance. - Mare Island Naval Shipyard, Magazine, Corbett Road, southwest end of Kieper Road, Vallejo, Solano County, CA

  7. Underground Test Area Subproject Project Management Plan, Revision 1

    SciTech Connect

    1998-06-03

    This Project Management Plan (PMP) describes the manner in which the US Department of Energy Nevada Operations Office (DOE/NV) will manage the Underground Test Area (UGTA) Subproject at the Nevada Test Site (NTS). It provides the basic guidance for implementation and the organizational structure for meeting the UGTA objectives.

  8. 200 Area Deactivation Project Facilities Authorization Envelope Document

    SciTech Connect

    DODD, E.N.

    2000-03-28

    Project facilities as required by HNF-PRO-2701, Authorization Envelope and Authorization Agreement. The Authorization Agreements (AA's) do not identify the specific set of environmental safety and health requirements that are applicable to the facility. Therefore, the facility Authorization Envelopes are defined here to identify the applicable requirements. This document identifies the authorization envelopes for the 200 Area Deactivation.

  9. Westside Area Career Occupations Project. Evaluation Report 1975-76.

    ERIC Educational Resources Information Center

    Glur, John

    Evaluation of the Westside Area Career Occupations Project (WACOP) focused on (1) examining what aspects of the Arizona career education effort had the most significant impact on students, and (2) measuring specific outcomes related to the students' knowledge about the world of work, using the Arizona Careers Test. System implementation and…

  10. Projected Bioclimatic Change for the San Francisco Bay Area

    NASA Astrophysics Data System (ADS)

    Torregrosa, A.; Taylor, M.; Flint, L. E.; Flint, A. L.; Weiss, S. B.

    2011-12-01

    Past and future climate data for the San Francisco Bay Area were classified using the Rivas-Martinez (R-M) system to group long-term annual climate averages into categories with biotic significance based on thermotypic and ombrotypic regimes. Bioclimate maps were generated at 270 meter resolution for ten San Francisco Bay Area counties for six 30-year periods from 1911 to 2100 which include the historical 1) 1911-1940, 2) 1941-1970, 3) 1971-2000, and future 4) 2011-2040, 5) 2041-2070, and 6) 2071-2100. Historic averages were generated from PRISM climate data. Future climate projections were generated from two IPCC-based future scenarios (A2 and B1) and two coupled atmosphere-ocean general circulation models (NOAA Geophysical Fluid Dynamics Laboratory and the Parallel Climate Model). Strong congruence was found among the boundaries for historic bioclimates and current vegetation types. However, future scenarios had varying patterns of losses and gains in bioclimate classes and these tracked mesoclimate gradients. Comparisons between projected bioclimatic categories and modeled future climatic water deficit show strong correspondence except in zones of deep alluvial deposits. Maps show areas of bioclimatic stability, e.g. areas that did not change under any future projection, versus areas with significant bioclimatic shifts in all future scenarios. These analyses and maps will be useful for assessing natural resource vulnerability to climate change and natural resource conservation-based climate adaptation decisions.

  11. Robust human detection, tracking, and recognition in crowded urban areas

    NASA Astrophysics Data System (ADS)

    Chen, Hai-Wen; McGurr, Mike

    2014-06-01

    In this paper, we present algorithms we recently developed to support an automated security surveillance system for very crowded urban areas. In our approach for human detection, the color features are obtained by taking the difference of R, G, B spectrum and converting R, G, B to HSV (Hue, Saturation, Value) space. Morphological patch filtering and regional minimum and maximum segmentation on the extracted features are applied for target detection. The human tracking process approach includes: 1) Color and intensity feature matching track candidate selection; 2) Separate three parallel trackers for color, bright (above mean intensity), and dim (below mean intensity) detections, respectively; 3) Adaptive track gate size selection for reducing false tracking probability; and 4) Forward position prediction based on previous moving speed and direction for continuing tracking even when detections are missed from frame to frame. The Human target recognition is improved with a Super-Resolution Image Enhancement (SRIE) process. This process can improve target resolution by 3-5 times and can simultaneously process many targets that are tracked. Our approach can project tracks from one camera to another camera with a different perspective viewing angle to obtain additional biometric features from different perspective angles, and to continue tracking the same person from the 2nd camera even though the person moved out of the Field of View (FOV) of the 1st camera with `Tracking Relay'. Finally, the multiple cameras at different view poses have been geo-rectified to nadir view plane and geo-registered with Google- Earth (or other GIS) to obtain accurate positions (latitude, longitude, and altitude) of the tracked human for pin-point targeting and for a large area total human motion activity top-view. Preliminary tests of our algorithms indicate than high probability of detection can be achieved for both moving and stationary humans. Our algorithms can simultaneously track

  12. Encoding of Human Action in Broca's Area

    ERIC Educational Resources Information Center

    Fazio, Patrik; Cantagallo, Anna; Craighero, Laila; D'Ausilio, Alessandro; Roy, Alice C.; Pozzo, Thierry; Calzolari, Ferdinando; Granieri, Enrico; Fadiga, Luciano

    2009-01-01

    Broca's area has been considered, for over a century, as the brain centre responsible for speech production. Modern neuroimaging and neuropsychological evidence have suggested a wider functional role is played by this area. In addition to the evidence that it is involved in syntactical analysis, mathematical calculation and music processing, it…

  13. TIMTEM project: our experience in a remote area.

    PubMed

    Zocco, G; Goletti, O; Lippolis, P V; Lorenzetti, L; Musco, B; Cavina, E; Tsolakidis, K

    2003-01-01

    We report our experience, begun in 1998 on a small island in the Dodecanese area of Greece, which has been called TIMTEM. The aim of this project was to improve care for people living on islands, creating a model exportable to other rural areas. The operative setting of the TIMTEM project is the island of Tilos (Greece); local authorities take part in it under the guidance of the only physician available on the island. The University of Pisa-Italy (Department of Surgery, Post-graduate School of Emergency Surgery) manages the scientific and organizational part of the project. Tilos is a rocky Mediterranean island with a surface of 64 km(2) and a population of about 500 inhabitants (with a peak of 2,000 tourists in July and August). A physician and a nurse are responsible for the only medical care on the island, and they also dispense drugs. The project was implemented on three phases. During the first phase, a campaign was held to encourage the population to cooperate with clinical data collection; a temporary telemedicine station was established, and a complete screening of the population was performed. The second phase was focused on the application of telesonography. During the third phase, a telematic and/or direct participation for reference hospital physicians (Regional Medical Society-Dodecanese) and for Greek physicians was planned. As well, a fully equipped central telemedicine station in the reference hospital was established under the local jurisdiction. The results of the third phase are still incomplete; the data presented here are preliminary. But all indicators show that the project is exportable to remote areas elsewhere. PMID:12699616

  14. Freihoelser Forst Local Training Area rehabilitation project. Final report

    SciTech Connect

    Hinchman, R.R.; Zellmer, S.D.; Johnson, D.O.; Severinghaus, W.D.; Brent, J.J.

    1991-12-01

    Intensive and continued use of the Freihoelser Forst Local Training Area (LTA) for military training activities had resulted in serious environmental problems, exemplified by a lack of vegetative cover and severe erosion by water and wind. The project`s goal was to develop and demonstrate rapid, cost-effective methods to stabilize the LTA`s barren, eroding maneuver areas and make training conditions more realistic. The major factors limiting rehabilitation efforts were the sandy, infertile, and acidic soils. The project was conducted in two phases. Phase I demonstrated and evaluated three separate rehabilitation treatments ranging in cost from moderate to expensive. Each treatment used a different type of soil amendment (fertilizer and straw, compost, or chicken manure), but all used identical seedbed preparation methods and seed mixtures. Phase I was conducted on relatively small replicated plots and was monitored three times during each growing season. All three treatments satisfactorily reestablished vegetation and controlled erosion. Because of their small size, the Phase I demonstration plots had only a minor stabilizing effect on the erosion problems of the LTA as a whole. The Phase II treatment was based on lessons teamed from Phase I and from other revegetation projects in Germany. Phase II revegetated a large area of the LTA, which included nearly all of the most severely disturbed land. Phase II, which was monitored in the same way as Phase I but for a shorter period of time, was highly successful in stabilizing most areas treated. The revegetation plant community was dominated by native grasses and legumes that stabilized the loose, sandy soils and improved the training realism of a major portion of the LTA.

  15. Mid-Plains Community College Area Human Resources Development Plan.

    ERIC Educational Resources Information Center

    Mid-Plains Community Coll. Area, North Platte, NE. Office of Institutional Research.

    This Human Resource Development Plan represents an effort to systematize human resources and personnel development at Mid-Plains Community College Area (MPCCA). The need for creating such a plan was specifically cited by North Central consultant evaluators, and a Human Resources Development (HRD) Steering Committee was established in spring 1994…

  16. Human occupation along the Steel Creek floodplain: results of an intensive archeological survey for the L area reactivation project, Savannah River Plant, Barnwell County, South Carolina. Research manuscript series 173

    SciTech Connect

    Hanson, G.T. Jr.; Brooks, R.D.; White, J.W.

    1981-12-01

    An intensive archeological survey of the Steel Creek terrace and floodplain system below the L Reactor Area was conducted for the purpose of identifying the archeological resources and assessing their significance within this portion of the Savannah River Plant. The survey was required as part of the project plan for the reactivation of the L Reactor in order to comply with the requirements of the National Environmental Policy Act of 1969, Executive Order 11593, the National Historic Preservation Act of 1966, as amended in 1980, and the Archeological and Historic Preservation of 1974. In accordance with these laws, a complete archeological survey of the potential impact area along Steel Creek was accomplished, resulting in the recovery of data for 18 archeological sites. According to the evidence recovered from the 18 sites, the Steel Creek watershed's occupation extends to at least 8000 B.P. Site 38BR55 is considered eligible for nomination to the National Register of Historic Places. Recommendations for the protection of this site and of four historic earthen structures in the floodplain are presented, along with a summary of the archeological background, methods, environmental reconstruction, research results, and recommendations resulting from the survey of the Steel Creek terrace and floodplain system.

  17. Human-Robot Interaction Directed Research Project

    NASA Technical Reports Server (NTRS)

    Sandor, Aniko; Cross, Ernest V., II; Chang, M. L.

    2014-01-01

    Human-robot interaction (HRI) is a discipline investigating the factors affecting the interactions between humans and robots. It is important to evaluate how the design of interfaces and command modalities affect the human's ability to perform tasks accurately, efficiently, and effectively when working with a robot. By understanding the effects of interface design on human performance, workload, and situation awareness, interfaces can be developed to appropriately support the human in performing tasks with minimal errors and with appropriate interaction time and effort. Thus, the results of research on human-robot interfaces have direct implications for the design of robotic systems. This DRP concentrates on three areas associated with interfaces and command modalities in HRI which are applicable to NASA robot systems: 1) Video Overlays, 2) Camera Views, and 3) Command Modalities. The first study focused on video overlays that investigated how Augmented Reality (AR) symbology can be added to the human-robot interface to improve teleoperation performance. Three types of AR symbology were explored in this study, command guidance (CG), situation guidance (SG), and both (SCG). CG symbology gives operators explicit instructions on what commands to input, whereas SG symbology gives operators implicit cues so that operators can infer the input commands. The combination of CG and SG provided operators with explicit and implicit cues allowing the operator to choose which symbology to utilize. The objective of the study was to understand how AR symbology affects the human operator's ability to align a robot arm to a target using a flight stick and the ability to allocate attention between the symbology and external views of the world. The study evaluated the effects type of symbology (CG and SG) has on operator tasks performance and attention allocation during teleoperation of a robot arm. The second study expanded on the first study by evaluating the effects of the type of

  18. Human-Robot Interaction Directed Research Project

    NASA Technical Reports Server (NTRS)

    Sandor, Aniko; Cross, Ernest V., II; Chang, Mai Lee

    2014-01-01

    Human-robot interaction (HRI) is a discipline investigating the factors affecting the interactions between humans and robots. It is important to evaluate how the design of interfaces and command modalities affect the human's ability to perform tasks accurately, efficiently, and effectively when working with a robot. By understanding the effects of interface design on human performance, workload, and situation awareness, interfaces can be developed to appropriately support the human in performing tasks with minimal errors and with appropriate interaction time and effort. Thus, the results of research on human-robot interfaces have direct implications for the design of robotic systems. This DRP concentrates on three areas associated with interfaces and command modalities in HRI which are applicable to NASA robot systems: 1) Video Overlays, 2) Camera Views, and 3) Command Modalities. The first study focused on video overlays that investigated how Augmented Reality (AR) symbology can be added to the human-robot interface to improve teleoperation performance. Three types of AR symbology were explored in this study, command guidance (CG), situation guidance (SG), and both (SCG). CG symbology gives operators explicit instructions on what commands to input, whereas SG symbology gives operators implicit cues so that operators can infer the input commands. The combination of CG and SG provided operators with explicit and implicit cues allowing the operator to choose which symbology to utilize. The objective of the study was to understand how AR symbology affects the human operator's ability to align a robot arm to a target using a flight stick and the ability to allocate attention between the symbology and external views of the world. The study evaluated the effects type of symbology (CG and SG) has on operator tasks performance and attention allocation during teleoperation of a robot arm. The second study expanded on the first study by evaluating the effects of the type of

  19. Project Management Methodology in Human Resource Management

    ERIC Educational Resources Information Center

    Josler, Cheryl; Burger, James

    2005-01-01

    When charged with overseeing a project, how can one ensure that the project will be completed on time, within budget, and to the satisfaction of everyone involved? In this article, the authors examine project management methodology as a means of ensuring that projects are conducted in a disciplined, well-managed and consistent manner that serves…

  20. The Human Genome Project: An Imperative for International Collaboration.

    ERIC Educational Resources Information Center

    Allende, J. E.

    1989-01-01

    Discussed is the Human Genome Project which aims to decipher the totality of the human genetic information. The historical background, the objectives, international cooperation, ethical discussion, and the role of UNESCO are included. (KR)

  1. Dopaminergic projections to the medial preoptic area of postpartum rats

    PubMed Central

    Miller, Stephanie M.; Lonstein, Joseph S.

    2010-01-01

    Dopamine receptor activity in the rodent medial preoptic area (mPOA) is crucial for the display of maternal behaviors, as well as numerous other physiological and behavioral functions. However, the origin of dopaminergic input to the mPOA has not been identified through neuroanatomical tracing. To accomplish this, the retrograde tracer Fluorogold was iontophoretically applied to the mPOA of postpartum laboratory rats, and dual-label immunocytochemistry for Fluorogold and tyrosine hydroxylase later performed to identify dopaminergic cells of the forebrain and midbrain projecting to the mPOA. Results indicate that the number of dopaminergic cells projecting to the mPOA is moderate (~90 cells to one hemisphere), and that these cells have an unexpectedly wide distribution. Even so, more than half of the dual-labeled cells were found in what has been considered extensions of the A10 dopamine group (particularly the ventrocaudal posterior hypothalamus and adjacent medial supramammillary nucleus), or in the A10 cells of the ventral tegmental area. The rostral hypothalamus and surrounding region also contained numerous dual-labeled cells, with the greatest number found within the mPOA itself (including in the AVPV and PVpo). Notably, dual-labeled cells were rare in the zona incerta (A13), a site previously suggested to provide dopaminergic input to the mPOA. This study is the first to use anatomical tracing to detail the dopaminergic projections to the mPOA in the laboratory rat, and indicates that much of this projection originates more caudally than previously suggested. PMID:19409227

  2. The Perseus Project and Beyond: How Building a Digital Library Challenges the Humanities and Technology.

    ERIC Educational Resources Information Center

    Crane, Gregory

    1998-01-01

    The Perseus Project, a digital library in the humanities concentrating on ancient Greek culture, is expanding to cover Roman, Renaissance and various other areas of the humanities. Goals include helping traditional scholars research effectively and help humanists use technology to redefine the relationship between their work and the broader…

  3. Leaf Area Index in Earth System Models: evaluation and projections

    NASA Astrophysics Data System (ADS)

    Mahowald, N.; Lo, F.; Zheng, Y.; Harrison, L.; Funk, C.; Lombardozzi, D.

    2015-04-01

    The amount of leaves in a plant canopy (measured as leaf area index, LAI) modulates key land-atmosphere interactions, including the exchange of energy, moisture, carbon dioxide (CO2), and other trace gases, and is therefore an essential variable in predicting terrestrial carbon, water, and energy fluxes. The latest generation of Earth system models (ESMs) simulate LAI, as well as provide projections of LAI in the future to improve simulations of biophysical and biogeochemical processes, and for use in climate impact studies. Here we use satellite measurements of LAI to answer the following questions: (1) are the models accurately simulating the mean LAI spatial distribution? (2) Are the models accurately simulating the seasonal cycle in LAI? (3) Are the models correctly simulating the processes driving interannual variability in the current climate? And finally based on this analysis, (4) can we reduce the uncertainty in future projections of LAI by using each model's skill in the current climate? Overall, models are able to capture some of the main characteristics of the LAI mean and seasonal cycle, but all of the models can be improved in one or more regions. Comparison of the modeled and observed interannual variability in the current climate suggested that in high latitudes the models may overpredict increases in LAI based on warming temperature, while in the tropics the models may overpredict the negative impacts of warming temperature on LAI. We expect, however, larger uncertainties in observational estimates of interannual LAI compared to estimates of seasonal or mean LAI. Future projections of LAI by the ESMs are largely optimistic, with only limited regions seeing reductions in LAI. Future projections of LAI in the models are quite different, and are sensitive to climate model projections of precipitation. They also strongly depend on the amount of carbon dioxide fertilization in high latitudes. Based on comparisons between model simulated LAI and observed

  4. Extrastriate projections in human optic radiation revealed by fMRI-informed tractography.

    PubMed

    Alvarez, Ivan; Schwarzkopf, D Samuel; Clark, Chris A

    2015-09-01

    The human optic radiation (OR) is the main pathway for conveying visual input to occipital cortex, but it is unclear whether it projects beyond primary visual cortex (V1). In this study, we used functional MRI mapping to delineate early visual areas in 30 healthy volunteers and determined the termination area of the OR as reconstructed with diffusion tractography. Direct thalamo-cortical projections to areas V2 and V3 were found in all hemispheres tested, with a distinct anatomical arrangement of superior-inferior fiber placement for dorsal and ventral projections, respectively, and a medio-lateral nesting arrangement for projections to V1, V2 and V3. Finally, segment-specific microstructure was examined, revealing sub-fascicular information. This is to date the first in vivo demonstration of direct extrastriate projections of the OR in humans. PMID:24903826

  5. Area recommendation report for the crystalline repository project: An evaluation. [Crystalline Repository Project

    SciTech Connect

    Beck, J E; Lowe, H; Yurkovich, S P

    1986-03-28

    An evaluation is given of DOE's recommendation of the Elk River complex in North Carolina for siting the second repository. Twelve recommendations are made including a strong suggestion that the Cherokee Tribe appeal both through political and legal avenues for inclusion as an affected area primarily due to projected impacts upon economy and public health as a consequence of the potential for reduced tourism.

  6. An anatomical and functional topography of human auditory cortical areas

    PubMed Central

    Moerel, Michelle; De Martino, Federico; Formisano, Elia

    2014-01-01

    While advances in magnetic resonance imaging (MRI) throughout the last decades have enabled the detailed anatomical and functional inspection of the human brain non-invasively, to date there is no consensus regarding the precise subdivision and topography of the areas forming the human auditory cortex. Here, we propose a topography of the human auditory areas based on insights on the anatomical and functional properties of human auditory areas as revealed by studies of cyto- and myelo-architecture and fMRI investigations at ultra-high magnetic field (7 Tesla). Importantly, we illustrate that—whereas a group-based approach to analyze functional (tonotopic) maps is appropriate to highlight the main tonotopic axis—the examination of tonotopic maps at single subject level is required to detail the topography of primary and non-primary areas that may be more variable across subjects. Furthermore, we show that considering multiple maps indicative of anatomical (i.e., myelination) as well as of functional properties (e.g., broadness of frequency tuning) is helpful in identifying auditory cortical areas in individual human brains. We propose and discuss a topography of areas that is consistent with old and recent anatomical post-mortem characterizations of the human auditory cortex and that may serve as a working model for neuroscience studies of auditory functions. PMID:25120426

  7. An anatomical and functional topography of human auditory cortical areas.

    PubMed

    Moerel, Michelle; De Martino, Federico; Formisano, Elia

    2014-01-01

    While advances in magnetic resonance imaging (MRI) throughout the last decades have enabled the detailed anatomical and functional inspection of the human brain non-invasively, to date there is no consensus regarding the precise subdivision and topography of the areas forming the human auditory cortex. Here, we propose a topography of the human auditory areas based on insights on the anatomical and functional properties of human auditory areas as revealed by studies of cyto- and myelo-architecture and fMRI investigations at ultra-high magnetic field (7 Tesla). Importantly, we illustrate that-whereas a group-based approach to analyze functional (tonotopic) maps is appropriate to highlight the main tonotopic axis-the examination of tonotopic maps at single subject level is required to detail the topography of primary and non-primary areas that may be more variable across subjects. Furthermore, we show that considering multiple maps indicative of anatomical (i.e., myelination) as well as of functional properties (e.g., broadness of frequency tuning) is helpful in identifying auditory cortical areas in individual human brains. We propose and discuss a topography of areas that is consistent with old and recent anatomical post-mortem characterizations of the human auditory cortex and that may serve as a working model for neuroscience studies of auditory functions. PMID:25120426

  8. Ground-water resources of Riverton irrigation project area, Wyoming

    USGS Publications Warehouse

    Morris, Donald Arthur; Hackett, O.M.; Vanlier, K.E.; Moulder, E.A.; Durum, W.H.

    1959-01-01

    The Riverton irrigation project area is in the northwestern part of the Wind River basin in west-central Wyoming. Because the annual precipitation is only about 9 inches, agriculture, which is the principal occupation in the area, is dependent upon irrigation. Irrigation by surface-water diversion was begum is 1906; water is now supplied to 77,716 acres and irrigation has been proposed for an additional 31,344 acres. This study of the geology and ground-water resources of the Riverton irrigation project, of adjacent irrigated land, and of nearby land proposed for irrigation was begun during the summer of 1948 and was completed in 1951. The purpose of the investigation was to evaluate the ground-water resources of the area and to study the factors that should be considered in the solution of drainage and erosional problems within the area. The Riverton irrigation project area is characterized by flat to gently sloping stream terraces, which are flanked by a combination of badlands, pediment slopes, and broad valleys. These features were formed by long-continued erosion in an arid climate of the essentially horizontal, poorly consolidated beds of the Wind River formation. The principal streams of the area flow south-eastward. Wind River and Fivemile Creek are perennial streams and the others are intermittent. Ground-water discharge and irrigation return flow have created a major problem in erosion control along Fivemile Creek. Similar conditions might develop along Muddy and lower Cottonwood Creeks when land in their drainage basins is irrigated. The bedrock exposed in the area ranges in age from Late Cretaceous to early Tertiary (middle Eocene). The Wind River formation of early and middle Eocene age forms the uppermost bedrock formation in the greater part of the area. Unconsolidated deposits of Quaternary age, which consist of terrace gravel, colluvium, eolian sand and silt. and alluvium, mantle the Wind River formation in much of the area. In the irrigated parts

  9. Terminal Area Productivity Program: Dynamic Spacing Human Factors

    NASA Technical Reports Server (NTRS)

    Kanki, Barbara G.

    1997-01-01

    Dynamic spacing human factors deals with the following human factors issues: define controller limits to incorporating dynamic changes in separation standards; identify timing, planning, and coordination strategies; and consider consistency with current practices, policies, and regulations. The AVOSS technologies will make it possible to reduce separation standards in the terminal area under certain meteorological conditions. This paper contains the following sections: Dynamic space human factors overview, Preliminary tests, and current research status & plans.

  10. Minimal Technologies Application Project, Hohenfels Training Area, Germany: Final report

    SciTech Connect

    Zellmer, S.D.; Hinchman, R.R.; Johnson, D.O. . Energy Systems Div.); Severinghaus, W.D. ); Brent, J.J. )

    1991-12-01

    At the US Army Hohenfels Training Area in Germany, more than 30 years of continuous and intensive tactical training has caused extensive environmental damage because of the loss of vegetative cover and accelerated soil erosion. A project was conducted to evaluate the cost-effectiveness and relative benefits of various revegetation procedures. These procedures involved amendment and seedbed preparation options that were combined with three different durations of site closure. The point-intercept method was used to measure the types and amounts of vegetation established and changes in the vegetative community. Over three growing seasons, applications of fertilizer and seed increased the percent grass, legume, and total vegetative cover. The duration of site closure had no influence on the types or amounts of ground cover established. Materials made up only 10% of the total cost of the fertilization and seeding operations. The results of the research indicate that less expensive methods of amendment application should be evaluated. The data also show that site closure is not practical, economical, or necessary. The results of this project suggest that a regular maintenance program consisting of seeding and fertilization is required to maintain adequate vegetative cover and control erosion on tactical training areas.

  11. Functional definitions of parietal areas in human and non-human primates

    PubMed Central

    Orban, Guy A.

    2016-01-01

    Establishing homologies between cortical areas in animal models and humans lies at the heart of translational neuroscience, as it demonstrates how knowledge obtained from these models can be applied to the human brain. Here, we review progress in using parallel functional imaging to ascertain homologies between parietal areas of human and non-human primates, species sharing similar behavioural repertoires. The human homologues of several areas along monkey IPS involved in action planning and observation, such as AIP, LIP and CIP, as well as those of opercular areas (SII complex), have been defined. In addition, uniquely human areas, such as the tool-use area in left anterior supramarginal gyrus, have also been identified. PMID:27053755

  12. Large-scale data mining pilot project in human genome

    SciTech Connect

    Musick, R.; Fidelis, R.; Slezak, T.

    1997-05-01

    This whitepaper briefly describes a new, aggressive effort in large- scale data Livermore National Labs. The implications of `large- scale` will be clarified Section. In the short term, this effort will focus on several @ssion-critical questions of Genome project. We will adapt current data mining techniques to the Genome domain, to quantify the accuracy of inference results, and lay the groundwork for a more extensive effort in large-scale data mining. A major aspect of the approach is that we will be fully-staffed data warehousing effort in the human Genome area. The long term goal is strong applications- oriented research program in large-@e data mining. The tools, skill set gained will be directly applicable to a wide spectrum of tasks involving a for large spatial and multidimensional data. This includes applications in ensuring non-proliferation, stockpile stewardship, enabling Global Ecology (Materials Database Industrial Ecology), advancing the Biosciences (Human Genome Project), and supporting data for others (Battlefield Management, Health Care).

  13. Advanced Large Area Plastic Scintillator Project (ALPS): Final Report

    SciTech Connect

    Jordan, David V.; Reeder, Paul L.; Todd, Lindsay C.; Warren, Glen A.; McCormick, Kathleen R.; Stephens, Daniel L.; Geelhood, Bruce D.; Alzheimer, James M.; Crowell, Shannon L.; Sliger, William A.

    2008-02-05

    The advanced Large-Area Plastic Scintillator (ALPS) Project at Pacific Northwest National Laboratory investigated possible technological avenues for substantially advancing the state-of-the-art in gamma-ray detection via large-area plastic scintillators. The three predominant themes of these investigations comprised the following: * Maximizing light collection efficiency from a single large-area sheet of plastic scintillator, and optimizing hardware event trigger definition to retain detection efficiency while exploiting the power of coincidence to suppress single-PMT "dark current" background; * Utilizing anti-Compton vetoing and supplementary spectral information from a co-located secondary, or "Back" detector, to both (1) minimize Compton background in the low-energy portion of the "Front" scintillator's pulse-height spectrum, and (2) sharpen the statistical accuracy of the front detector's low-energy response prediction as impelmented in suitable energy-windowing algorithms; and * Investigating alternative materials to enhance the intrinsic gamma-ray detection efficiency of plastic-based sensors.

  14. The Human Genome Project: how do we protect Australians?

    PubMed

    Stott Despoja, N

    It is the moon landing of the nineties: the ambitious Human Genome Project--identifying the up to 100,000 genes that make up human DNA and the sequences of the three billion base-pairs that comprise the human genome. However, unlike the moon landing, the effects of the genome project will have a fundamental impact on the way we see ourselves and each other. PMID:11379500

  15. Groundwater Monitoring Report Project Shoal Area, Corrective Action Unit 447

    SciTech Connect

    2008-01-01

    This report presents the 2007 groundwater monitoring results collected by the U.S. Department of Energy (DOE) Office of Legacy Management (LM) at the Project Shoal Area (PSA) Corrective Action Unit (CAU) 447 located in Churchill County, Nevada. Responsibility for the environmental site restoration of the PSA was transferred from the DOE Office of Environmental Management (DOE-EM) to DOE-LM on October 1, 2006. Requirements for CAU 447, as specified in the Federal Facility Agreement and Consent Order (FFACO 2005) entered into by DOE, the U.S. Department of Defense (DOD), and the State of Nevada, includes groundwater monitoring in support of site closure. This is the first groundwater monitoring report prepared by DOE-LM for the PSA.

  16. Closure report for CAU No. 416: Project Shoal Area

    SciTech Connect

    1998-01-01

    This Closure Report provides the documentation for closure of the US Department of Energy/Nevada Operations Office (DOE/NV) Project Shoal Area (PSA) Surface Corrective Action Unit (CAU) 416. CAU 416 consists of a mud pit, muckpile, and housekeeping site. The PSA is located approximately 48.3 kilometers (30 miles) southeast of Fallon, Nevada. The mud pit was the result of drilling activities at the PSA in 1963. Investigation activities completed in 1996 determined drilling mud in the mud pit was impacted with petroleum hydrocarbons in excess of the State of Nevada 100 milligram per kilogram (mg/kg). The muckpile consists of broken granite from emplacement shaft and drift (tunnel) mining activities at the PSA in 1963. The housekeeping site consisted of approximately 20 used, empty, rusted, steel 0.9 liter (1 quart) oil cans.

  17. 76 FR 1429 - Loveland Area Projects/Western Area Colorado Missouri Balancing Authority-Rate Order No. WAPA-154

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-10

    ... through February 28, 2011. 73 FR 48382, August 19, 2008. \\3\\ WAPA-118 was approved by FERC on a final... Area Power Administration Loveland Area Projects/Western Area Colorado Missouri Balancing Authority--Rate Order No. WAPA-154 AGENCY: Western Area Power Administration, DOE. ACTION: Notice of Rate...

  18. Draft environmental assessment -- Test Area North pool stabilization project update

    SciTech Connect

    1997-06-01

    The purpose of this Environmental Assessment (EA) is to update the ``Test Area North Pool Stabilization Project`` EA (DOE/EA-1050) and finding of no significant impact (FONSI) issued May 6, 1996. This update analyzes the environmental and health impacts of a drying process for the Three Mile Island (TMI) nuclear reactor core debris canisters now stored underwater in a facility on the Idaho National Engineering and Environmental Laboratory (INEEL). A drying process was analyzed in the predecision versions of the EA released in 1995 but that particular process was determined to be ineffective and dropped form the Ea/FONSI issued May 6, 1996. The origin and nature of the TMI core debris and the proposed drying process are described and analyzed in detail in this EA. As did the 1996 EA, this update analyzes the environmental and health impacts of removing various radioactive materials from underwater storage, dewatering these materials, constructing a new interim dry storage facility, and transporting and placing the materials into the new facility. Also, as did the 1996 EA, this EA analyzes the removal, treatment and disposal of water from the pool, and placement of the facility into a safe, standby condition. The entire action would take place within the boundaries of the INEEL. The materials are currently stored underwater in the Test Area North (TAN) building 607 pool, the new interim dry storage facility would be constructed at the Idaho Chemical Processing Plant (ICPP) which is about 25 miles south of TAN.

  19. Environmental Assessment -- Test Area North pool stabilization project update

    SciTech Connect

    1997-08-01

    The purpose of this Environmental Assessment (EA) is to update the ``Test Area North Pool Stabilization Project`` EA (DOE/EA-1050) and finding of no significant impact (FONSI) issued May 6, 1996. This update analyzes the environmental and health impacts of a drying process for the Three Mile Island (TMI) nuclear reactor core debris canisters now stored underwater in a facility on the Idaho National Engineering and Environmental Laboratory (INEEL). A drying process was analyzed in the predecision versions of the EA released in 1995 but that particular process was determined to be ineffective and dropped from the EA/FONSI issued May 6, 1996. A new drying process was subsequently developed and is analyzed in Section 2.1.2 of this document. As did the 1996 EA, this update analyzes the environmental and health impacts of removing various radioactive materials from underwater storage, dewatering these materials, constructing a new interim dry storage facility, and transporting and placing the materials into the new facility. Also, as did the 1996 EA, this EA analyzes the removal, treatment and disposal of water from the pool, and placement of the facility into a safe, standby condition. The entire action would take place within the boundaries of the INEEL. The materials are currently stored underwater in the Test Area North (TAN) building 607 pool, the new interim dry storage facility would be constructed at the Idaho Chemical Processing Plant (ICPP) which is about 25 miles south of TAN.

  20. Earthquake supersite project in the Messina Straits area (EQUAMES)

    NASA Astrophysics Data System (ADS)

    Mattia, Mario; Chiarabba, Claudio; Dell'Acqua, Fabio; Faccenna, Claudio; Lanari, Riccardo; Matteuzzi, Francesco; Neri, Giancarlo; Patanè, Domenico; Polonia, Alina; Prati, Claudio; Tinti, Stefano; Zerbini, Susanna

    2015-04-01

    A new permanent supersite is going to be proposed to the GEO GSNL (Geohazard Supersites and National Laboratories) for the Messina Straits area (Italy). The justification for this new supersite can be found in its geological and geophysical features and in the exposure to strong earthquakes, also in the recent past (1908). The Messina Supersite infrastructure (EQUAMES: EarthQUAkes in the MEssina Straits) will host, and contribute to the collection of, large amounts of data, basic for the analysis of seismic hazard/risk in this high seismic risk area, including risk from earthquake-related processes such as submarine mass failures and tsunamis. In EQUAMES, data of different types will coexist with models and methods useful for their analysis/interpretation and with first-level products of analysis that can be of interest for different kinds of users. EQUAMES will help all the interested scientific and non-scientific subjects to find and use data and to increase inter-institutional cooperation by addressing the following main topics in the Messina Straits area: • investigation of the geological and physical processes leading to the earthquake preparation and generation; • analysis of seismic shaking at ground (expected and observed); • combination of seismic hazard with vulnerability and exposure data for risk estimates; • analysis of tsunami generation, propagation and coastal inundation deriving from earthquake occurrence also through landslides due to instability conditions of subaerial and submarine slopes; • overall risk associated to earthquake activity in the Supersite area including the different types of cascade effects Many Italian and international Institutions have shown an effective interest in this project where a large variety of geophysical and geological in-situ data will be collected and where the INGV has the leading role with its large infrastructure of seismic, GPS and geochemical permanent stations. The groups supporting EQUAMES

  1. Evansville Area Earthquake Hazards Mapping Project (EAEHMP) - Progress Report, 2008

    USGS Publications Warehouse

    Boyd, Oliver S.; Haase, Jennifer L.; Moore, David W.

    2009-01-01

    Maps of surficial geology, deterministic and probabilistic seismic hazard, and liquefaction potential index have been prepared by various members of the Evansville Area Earthquake Hazard Mapping Project for seven quadrangles in the Evansville, Indiana, and Henderson, Kentucky, metropolitan areas. The surficial geologic maps feature 23 types of surficial geologic deposits, artificial fill, and undifferentiated bedrock outcrop and include alluvial and lake deposits of the Ohio River valley. Probabilistic and deterministic seismic hazard and liquefaction hazard mapping is made possible by drawing on a wealth of information including surficial geologic maps, water well logs, and in-situ testing profiles using the cone penetration test, standard penetration test, down-hole shear wave velocity tests, and seismic refraction tests. These data were compiled and collected with contributions from the Indiana Geological Survey, Kentucky Geological Survey, Illinois State Geological Survey, United States Geological Survey, and Purdue University. Hazard map products are in progress and are expected to be completed by the end of 2009, with a public roll out in early 2010. Preliminary results suggest that there is a 2 percent probability that peak ground accelerations of about 0.3 g will be exceeded in much of the study area within 50 years, which is similar to the 2002 USGS National Seismic Hazard Maps for a firm rock site value. Accelerations as high as 0.4-0.5 g may be exceeded along the edge of the Ohio River basin. Most of the region outside of the river basin has a low liquefaction potential index (LPI), where the probability that LPI is greater than 5 (that is, there is a high potential for liquefaction) for a M7.7 New Madrid type event is only 20-30 percent. Within the river basin, most of the region has high LPI, where the probability that LPI is greater than 5 for a New Madrid type event is 80-100 percent.

  2. Design Projects in Human Anatomy & Physiology

    ERIC Educational Resources Information Center

    Polizzotto, Kristin; Ortiz, Mary T.

    2008-01-01

    Very often, some type of writing assignment is required in college entry-level Human Anatomy and Physiology courses. This assignment can be anything from an essay to a research paper on the literature, focusing on a faculty-approved topic of interest to the student. As educators who teach Human Anatomy and Physiology at an urban community college,…

  3. 7 CFR 1468.4 - Establishing Conservation Farm Option (CFO) pilot project areas.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... project areas. 1468.4 Section 1468.4 Agriculture Regulations of the Department of Agriculture (Continued... FARM OPTION General Provisions § 1468.4 Establishing Conservation Farm Option (CFO) pilot project areas. (a) CCC may periodically solicit proposals from the public to establish pilot project areas in...

  4. 7 CFR 1468.4 - Establishing Conservation Farm Option (CFO) pilot project areas.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... project areas. 1468.4 Section 1468.4 Agriculture Regulations of the Department of Agriculture (Continued... FARM OPTION General Provisions § 1468.4 Establishing Conservation Farm Option (CFO) pilot project areas. (a) CCC may periodically solicit proposals from the public to establish pilot project areas in...

  5. 7 CFR 1468.4 - Establishing Conservation Farm Option (CFO) pilot project areas.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... project areas. 1468.4 Section 1468.4 Agriculture Regulations of the Department of Agriculture (Continued... FARM OPTION General Provisions § 1468.4 Establishing Conservation Farm Option (CFO) pilot project areas. (a) CCC may periodically solicit proposals from the public to establish pilot project areas in...

  6. 7 CFR 1468.4 - Establishing Conservation Farm Option (CFO) pilot project areas.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... project areas. 1468.4 Section 1468.4 Agriculture Regulations of the Department of Agriculture (Continued... FARM OPTION General Provisions § 1468.4 Establishing Conservation Farm Option (CFO) pilot project areas. (a) CCC may periodically solicit proposals from the public to establish pilot project areas in...

  7. 7 CFR 1468.4 - Establishing Conservation Farm Option (CFO) pilot project areas.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... project areas. 1468.4 Section 1468.4 Agriculture Regulations of the Department of Agriculture (Continued... FARM OPTION General Provisions § 1468.4 Establishing Conservation Farm Option (CFO) pilot project areas. (a) CCC may periodically solicit proposals from the public to establish pilot project areas in...

  8. 7 CFR 275.18 - Project area/management unit corrective action plan.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 4 2013-01-01 2013-01-01 false Project area/management unit corrective action plan... SYSTEM Corrective Action § 275.18 Project area/management unit corrective action plan. (a) The State agency shall ensure that corrective action plans are prepared at the project area/management unit...

  9. 7 CFR 275.18 - Project area/management unit corrective action plan.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Project area/management unit corrective action plan... SYSTEM Corrective Action § 275.18 Project area/management unit corrective action plan. (a) The State agency shall ensure that corrective action plans are prepared at the project area/management unit...

  10. 7 CFR 275.18 - Project area/management unit corrective action plan.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false Project area/management unit corrective action plan... SYSTEM Corrective Action § 275.18 Project area/management unit corrective action plan. (a) The State agency shall ensure that corrective action plans are prepared at the project area/management unit...

  11. 7 CFR 275.18 - Project area/management unit corrective action plan.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false Project area/management unit corrective action plan... SYSTEM Corrective Action § 275.18 Project area/management unit corrective action plan. (a) The State agency shall ensure that corrective action plans are prepared at the project area/management unit...

  12. 7 CFR 275.18 - Project area/management unit corrective action plan.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 4 2012-01-01 2012-01-01 false Project area/management unit corrective action plan... SYSTEM Corrective Action § 275.18 Project area/management unit corrective action plan. (a) The State agency shall ensure that corrective action plans are prepared at the project area/management unit...

  13. Intraskeletal Variability of Relative Cortical Area in Humans.

    PubMed

    Stewart, Marissa C; Goliath, Jesse R; Stout, Sam D; Hubbe, Mark

    2015-09-01

    Histomorphometric and cross-sectional geometric studies of bone have provided valuable information about age at death, behavioral and activity patterns, and pathological conditions for past and present human populations. While a considerable amount of exploratory and applied research has been completed using histomorphometric and cross-sectional geometric properties, the effects of intraskeletal variability on interpreting observed histomorphometric data have not been fully explored. The purpose of this study is to quantify intraskeletal variability in the relative cortical area of long bones and ribs from modern humans. To examine intraskeletal variability, cross-sections of the femur, tibia, fibula, humerus, radius, ulna, and rib when present, were examined within individuals from a cadaveric collection (N = 34). Relative cortical area was compared within individuals using a repeated measurements General Linear Model, which shows significant differences between bones, particularly between the rib and the remaining long bones. Complementarily, correlations between bones' relative cortical area values suggest an important allometric component affecting this aspect of long bones, but not of the rib. This study highlights the magnitude of intraskeletal variability in relative cortical area in the human skeleton, and because the relative cortical area of any particular bone is affected by a series of confounding factors, extrapolation of relative cortical area values to infer load history for other skeletal elements can be misleading. PMID:26058578

  14. Global Projections of 21st Century Land-Use Changes in Regions Adjacent to Protected Areas

    PubMed Central

    Beaumont, Linda J.; Duursma, Daisy

    2012-01-01

    The conservation efficiency of Protected Areas (PA) is influenced by the health and characteristics of the surrounding landscape matrix. Fragmentation of adjacent lands interrupts ecological flows within PAs and will decrease the ability of species to shift their distribution as climate changes. For five periods across the 21st century, we assessed changes to the extent of primary land, secondary land, pasture and crop land projected to occur within 50 km buffers surrounding IUCN-designated PAs. Four scenarios of land-use were obtained from the Land-Use Harmonization Project, developed for the Intergovernmental Panel on Climate Change's Fifth Assessment Report (AR5). The scenarios project the continued decline of primary lands within buffers surrounding PAs. Substantial losses are projected to occur across buffer regions in the tropical forest biomes of Indo-Malayan and the Temperate Broadleaf forests of the Nearctic. A number of buffer regions are projected to have negligible primary land remaining by 2100, including those in the Afrotropic's Tropical/Subtropical Grassland/Savanna/Shrubland. From 2010–2050, secondary land is projected to increase within most buffer regions, although, as with pasture and crops within tropical and temperate forests, projections from the four land-use scenarios may diverge substantially in magnitude and direction of change. These scenarios demonstrate a range of alternate futures, and show that although effective mitigation strategies may reduce pressure on land surrounding PAs, these areas will contain an increasingly heterogeneous matrix of primary and human-modified landscapes. Successful management of buffer regions will be imperative to ensure effectiveness of PAs and to facilitate climate-induced shifts in species ranges. PMID:22952744

  15. The lawful uses of knowledge from the Human Genome Project

    SciTech Connect

    Grad, F.P.

    1994-04-15

    Part I of this study deals with the right to know or not to know personal genetic information, and examines available legal protections of the right of privacy and the adverse effect of the disclosure of genetic information both on employment and insurance interests and on self esteem and protection of personal integrity. The study examines the rationale for the legal protection of privacy as the protection of a public interest. It examines the very limited protections currently available for privacy interests, including genetic privacy interests, and concludes that there is a need for broader, more far-reaching legal protections. The second part of the study is based on the assumption that as major a project as the Human Genome Project, spending billions of dollars on science which is health related, will indeed be applied for preventive and therapeutic public health purposes, as it has been in the past. It also addresses the recurring fear that public health initiatives in the genetic area must evolve a new eugenic agenda, that we must not repeat the miserable discriminatory experiences of the past.

  16. Mapping striate and extrastriate visual areas in human cerebral cortex.

    PubMed Central

    DeYoe, E A; Carman, G J; Bandettini, P; Glickman, S; Wieser, J; Cox, R; Miller, D; Neitz, J

    1996-01-01

    Functional magnetic resonance imaging (fMRI) was used to identify and map the representation of the visual field in seven areas of human cerebral cortex and to identify at least two additional visually responsive regions. The cortical locations of neurons responding to stimulation along the vertical or horizontal visual field meridia were charted on three-dimensional models of the cortex and on unfolded maps of the cortical surface. These maps were used to identify the borders among areas that would be topographically homologous to areas V1, V2, V3, VP, and parts of V3A and V4 of the macaque monkey. Visually responsive areas homologous to the middle temporal/medial superior temporal area complex and unidentified parietal visual areas were also observed. The topography of the visual areas identified thus far is consistent with the organization in macaque monkeys. However, these and other findings suggest that human and simian cortical organization may begin to differ in extrastriate cortex at, or beyond, V3A and V4. Images Fig. 1 Fig. 2 Fig. 3 Fig. 4 Fig. 5 PMID:8637882

  17. European approach to the Human Gene Project.

    PubMed

    Ferguson-Smith, M A

    1991-01-01

    In the history of gene mapping, which extends through most of the present century, Europe has played an important role. This has continued during the evolution of the 10 International Human Gene Mapping Workshops that have been held in seven different countries since 1973. Nationally coordinated programs have been a recent development, and several European countries, including the United Kingdom and Italy, have followed the lead of the United States in investing substantial sums of money in research on the human genome. In addition, the European Community has launched a multinational program of research on Human Genome Analysis to complement the various national initiatives. The particular approach in Europe has been to support those in the field by establishing resource centers for distributing biomaterials and accessing databases, by assisting in the training of scientists, and by funding programs of research directed at present needs in both physical and genetic mapping. PMID:1991586

  18. AC Electric Field Communication for Human-Area Networking

    NASA Astrophysics Data System (ADS)

    Kado, Yuichi; Shinagawa, Mitsuru

    We have proposed a human-area networking technology that uses the surface of the human body as a data transmission path and uses an AC electric field signal below the resonant frequency of the human body. This technology aims to achieve a “touch and connect” intuitive form of communication by using the electric field signal that propagates along the surface of the human body, while suppressing both the electric field radiating from the human body and mutual interference. To suppress the radiation field, the frequency of the AC signal that excites the transmitter electrode must be lowered, and the sensitivity of the receiver must be raised while reducing transmission power to its minimally required level. We describe how we are developing AC electric field communication technologies to promote the further evolution of a human-area network in support of ubiquitous services, focusing on three main characteristics, enabling-transceiver technique, application-scenario modeling, and communications quality evaluation. Special attention is paid to the relationship between electro-magnetic compatibility evaluation and regulations for extremely low-power radio stations based on Japan's Radio Law.

  19. Democratizing Human Genome Project Information: A Model Program for Education, Information and Debate in Public Libraries.

    ERIC Educational Resources Information Center

    Pollack, Miriam

    The "Mapping the Human Genome" project demonstrated that librarians can help whomever they serve in accessing information resources in the areas of biological and health information, whether it is the scientists who are developing the information or a member of the public who is using the information. Public libraries can guide library users…

  20. Body mass scaling of projected frontal area in competitive cyclists.

    PubMed

    Heil, D P

    2001-08-01

    The primary purpose of this study was to evaluate the scaling relationship between body mass (mb) and projected frontal area (AP) of competitive male cyclists whilst allowing statistically for the influence of bicycle geometry. A group of 21 cyclists [mean mb 74.4 (SD 7.2) kg, mean height 1.82 (SD 0.06) m, mean age 23.6 (SD 5.1) years] volunteered to have AP determined from photographs at three trunk angles (TA: 5 degrees, 15 degrees, 25 degrees) for each of three seat-tube angles (STA: 70 degrees, 75 degrees, 80 degrees) using a modified cycle ergometer. Using multiple log-linear regression analysis procedures, the following equation was developed: Body AP (meters squared) = 0.00433 x (STA0.172) x (TA0.0965) x (mb0.762) (r2 = 0.73, SEE = 0.017 m2) (n = 183 images total). This equation indicates that after allowing for the independent influence of STA and TA on AP, AP was proportional to mb raised to the +0.762 power (i.e. Ap is directly proportional to 0.762). The 95% confidence interval for this exponent (0.670-0.854) barely included the theoretical two-thirds value but not the +0.55 value for AP or the +0.32 value for submaximal metabolic power (Ws) of outdoor cycling reported in the literature. Further analysis of wind tunnel data reported in the literature suggests that the coefficient of drag (CD) is proportional to mb raised to the -0.45 power. When combined with the present study findings, it is suggested that the drag area (CD x AP), which should be proportional to Ws at submaximal cycling velocities, is proportional to mb to the +0.312 power (i.e. CD x AP is directly proportional to mb-0.45) x (mb+0.762) = mb+0.312), which is consistent with the +0.32 exponent for Ws in the literature. PMID:11560092

  1. Human Activity Recognition in AAL Environments Using Random Projections.

    PubMed

    Damaševičius, Robertas; Vasiljevas, Mindaugas; Šalkevičius, Justas; Woźniak, Marcin

    2016-01-01

    Automatic human activity recognition systems aim to capture the state of the user and its environment by exploiting heterogeneous sensors attached to the subject's body and permit continuous monitoring of numerous physiological signals reflecting the state of human actions. Successful identification of human activities can be immensely useful in healthcare applications for Ambient Assisted Living (AAL), for automatic and intelligent activity monitoring systems developed for elderly and disabled people. In this paper, we propose the method for activity recognition and subject identification based on random projections from high-dimensional feature space to low-dimensional projection space, where the classes are separated using the Jaccard distance between probability density functions of projected data. Two HAR domain tasks are considered: activity identification and subject identification. The experimental results using the proposed method with Human Activity Dataset (HAD) data are presented. PMID:27413392

  2. Human Activity Recognition in AAL Environments Using Random Projections

    PubMed Central

    Damaševičius, Robertas; Vasiljevas, Mindaugas; Šalkevičius, Justas; Woźniak, Marcin

    2016-01-01

    Automatic human activity recognition systems aim to capture the state of the user and its environment by exploiting heterogeneous sensors attached to the subject's body and permit continuous monitoring of numerous physiological signals reflecting the state of human actions. Successful identification of human activities can be immensely useful in healthcare applications for Ambient Assisted Living (AAL), for automatic and intelligent activity monitoring systems developed for elderly and disabled people. In this paper, we propose the method for activity recognition and subject identification based on random projections from high-dimensional feature space to low-dimensional projection space, where the classes are separated using the Jaccard distance between probability density functions of projected data. Two HAR domain tasks are considered: activity identification and subject identification. The experimental results using the proposed method with Human Activity Dataset (HAD) data are presented. PMID:27413392

  3. A Cell-Based Approach to the Human Proteome Project

    NASA Astrophysics Data System (ADS)

    Kelleher, Neil L.

    2012-10-01

    The general scope of a project to determine the protein molecules that comprise the cells within the human body is framed. By focusing on protein primary structure as expressed in specific cell types, this concept for a cell-based version of the Human Proteome Project (CB-HPP) is crafted in a manner analogous to the Human Genome Project while recognizing that cells provide a primary context in which to define a proteome. Several activities flow from this articulation of the HPP, which enables the definition of clear milestones and deliverables. The CB-HPP highlights major gaps in our knowledge regarding cell heterogeneity and protein isoforms, and calls for development of technology that is capable of defining all human cell types and their proteomes. The main activities will involve mapping and sorting cell types combined with the application of beyond the state-of-the art in protein mass spectrometry.

  4. Cytology and Functionally Correlated Circuits of Human Posterior Cingulate Areas

    PubMed Central

    Vogt, Brent A.; Vogt, Leslie; Laureys, Steven

    2008-01-01

    Human posterior cingulate cortex (PCC) and retrosplenial cortex (RSC) form the posterior cingulate gyrus, however, monkey connection and human imaging studies suggest that PCC area 23 is not uniform and atlases mislocate RSC. We histologically assessed these regions in 6 postmortem cases, plotted a flat map, and characterized differences in dorsal (d) and ventral (v) area 23. Subsequently, functional connectivity of histologically guided regions of interest (ROI) were assessed in 163 [18F]fluorodeoxyglucose human cases with PET. Compared to area d23, area v23 had a higher density and larger pyramids in layers II, IIIc, and Vb and more intermediate neurofilament-expressing neurons in layer Va. Coregisrtration of each case to standard coordinates showed that the ventral branch of the splenial sulci coincided with the border between d/v PCC at −5.4±0.17 cm from the vertical plane and +1.97±0.08 cm from the bi-commissural line. Correlation analysis of glucose metabolism using histologically guided ROIs suggested important circuit differences including dorsal and ventral visual stream inputs, interactions between the vPCC and subgenual cingulate cortex, and preferential relations between dPCC and the cingulate motor region. The RSC, in contrast, had restricted correlated activity with pericallosal cortex and thalamus. Visual information may be processed with an orbitofrontal link for synthesis of signals to drive premotor activity through dPCC. Review of the literature in terms of a PCC duality suggests that interactions of dPCC, including area 23d, orients the body in space via the cingulate motor areas, while vPCC interacts with subgenual cortex to process self-relevant emotional and non-emotional information and objects and self reflection. PMID:16140550

  5. [Discussion on water conservancy projects and schistosomiasis control in Poyang Lake area].

    PubMed

    Liu, Dao-Nan

    2013-02-01

    According to the schistosomiasis endemic situation in the Poyang Lake area, this paper analyzes the relationship between the water conservancy projects and schistosomiasis control, and reviews and discusses the effects of the Water Level Control Project of Poyang Lake, the Lake Dike Slope Hardening Project, and the Lifting Delta and Descending Beach Project on Oncomelania snail control. PMID:23687826

  6. The Human Proteome Project: Current State and Future Direction

    PubMed Central

    Legrain, Pierre; Aebersold, Ruedi; Archakov, Alexander; Bairoch, Amos; Bala, Kumar; Beretta, Laura; Bergeron, John; Borchers, Christoph H.; Corthals, Garry L.; Costello, Catherine E.; Deutsch, Eric W.; Domon, Bruno; Hancock, William; He, Fuchu; Hochstrasser, Denis; Marko-Varga, György; Salekdeh, Ghasem Hosseini; Sechi, Salvatore; Snyder, Michael; Srivastava, Sudhir; Uhlén, Mathias; Wu, Cathy H.; Yamamoto, Tadashi; Paik, Young-Ki; Omenn, Gilbert S.

    2011-01-01

    After the successful completion of the Human Genome Project, the Human Proteome Organization has recently officially launched a global Human Proteome Project (HPP), which is designed to map the entire human protein set. Given the lack of protein-level evidence for about 30% of the estimated 20,300 protein-coding genes, a systematic global effort will be necessary to achieve this goal with respect to protein abundance, distribution, subcellular localization, interaction with other biomolecules, and functions at specific time points. As a general experimental strategy, HPP research groups will use the three working pillars for HPP: mass spectrometry, antibody capture, and bioinformatics tools and knowledge bases. The HPP participants will take advantage of the output and cross-analyses from the ongoing Human Proteome Organization initiatives and a chromosome-centric protein mapping strategy, termed C-HPP, with which many national teams are currently engaged. In addition, numerous biologically driven and disease-oriented projects will be stimulated and facilitated by the HPP. Timely planning with proper governance of HPP will deliver a protein parts list, reagents, and tools for protein studies and analyses, and a stronger basis for personalized medicine. The Human Proteome Organization urges each national research funding agency and the scientific community at large to identify their preferred pathways to participate in aspects of this highly promising project in a HPP consortium of funders and investigators. PMID:21742803

  7. The human proteome project: current state and future direction.

    PubMed

    Legrain, Pierre; Aebersold, Ruedi; Archakov, Alexander; Bairoch, Amos; Bala, Kumar; Beretta, Laura; Bergeron, John; Borchers, Christoph H; Corthals, Garry L; Costello, Catherine E; Deutsch, Eric W; Domon, Bruno; Hancock, William; He, Fuchu; Hochstrasser, Denis; Marko-Varga, György; Salekdeh, Ghasem Hosseini; Sechi, Salvatore; Snyder, Michael; Srivastava, Sudhir; Uhlén, Mathias; Wu, Cathy H; Yamamoto, Tadashi; Paik, Young-Ki; Omenn, Gilbert S

    2011-07-01

    After the successful completion of the Human Genome Project, the Human Proteome Organization has recently officially launched a global Human Proteome Project (HPP), which is designed to map the entire human protein set. Given the lack of protein-level evidence for about 30% of the estimated 20,300 protein-coding genes, a systematic global effort will be necessary to achieve this goal with respect to protein abundance, distribution, subcellular localization, interaction with other biomolecules, and functions at specific time points. As a general experimental strategy, HPP research groups will use the three working pillars for HPP: mass spectrometry, antibody capture, and bioinformatics tools and knowledge bases. The HPP participants will take advantage of the output and cross-analyses from the ongoing Human Proteome Organization initiatives and a chromosome-centric protein mapping strategy, termed C-HPP, with which many national teams are currently engaged. In addition, numerous biologically driven and disease-oriented projects will be stimulated and facilitated by the HPP. Timely planning with proper governance of HPP will deliver a protein parts list, reagents, and tools for protein studies and analyses, and a stronger basis for personalized medicine. The Human Proteome Organization urges each national research funding agency and the scientific community at large to identify their preferred pathways to participate in aspects of this highly promising project in a HPP consortium of funders and investigators. PMID:21742803

  8. Local Area Networks--The ENFI Project (Writing on the College Campus).

    ERIC Educational Resources Information Center

    Stine, Linda

    1989-01-01

    Describes Electronic Networks for Interaction (ENFI), a local area network project developed at Gallaudet University to empower students with hearing impairments. Notes that this project can be adapted easily for use with traditional students. (MM)

  9. Large rainfall changes consistently projected over substantial areas of tropical land

    NASA Astrophysics Data System (ADS)

    Chadwick, Robin; Good, Peter; Martin, Gill; Rowell, David P.

    2016-02-01

    Many tropical countries are exceptionally vulnerable to changes in rainfall patterns, with floods or droughts often severely affecting human life and health, food and water supplies, ecosystems and infrastructure. There is widespread disagreement among climate model projections of how and where rainfall will change over tropical land at the regional scales relevant to impacts, with different models predicting the position of current tropical wet and dry regions to shift in different ways. Here we show that despite uncertainty in the location of future rainfall shifts, climate models consistently project that large rainfall changes will occur for a considerable proportion of tropical land over the twenty-first century. The area of semi-arid land affected by large changes under a higher emissions scenario is likely to be greater than during even the most extreme regional wet or dry periods of the twentieth century, such as the Sahel drought of the late 1960s to 1990s. Substantial changes are projected to occur by mid-century--earlier than previously expected--and to intensify in line with global temperature rise. Therefore, current climate projections contain quantitative, decision-relevant information on future regional rainfall changes, particularly with regard to climate change mitigation policy.

  10. Underground Test Area Project Waste Management Plan (Rev. No. 2, April 2002)

    SciTech Connect

    IT Corporation, Las Vegas

    2002-04-24

    The U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Operations Office (NNSA/NV) initiated the UGTA Project to characterize the risk posed to human health and the environment as a result of underground nuclear testing activities at the Nevada Test Site (NTS). The UGTA Project investigation sites have been grouped into Corrective Action Units (CAUs) in accordance with the most recent version of the Federal Facility Agreement and Consent Order. The primary UGTA objective is to gather data to characterize the groundwater aquifers beneath the NTS and adjacent lands. The investigations proposed under the UGTA program may involve the drilling and sampling of new wells; recompletion, monitoring, and sampling of existing wells; well development and hydrologic/ aquifer testing; geophysical surveys; and subsidence crater recharge evaluation. Those wastes generated as a result of these activities will be managed in accordance with existing federal and state regulations, DOE Orders, and NNSA/NV waste minimization and pollution prevention objectives. This Waste Management Plan provides a general framework for all Underground Test Area (UGTA) Project participants to follow for the characterization, storage/accumulation, treatment, and disposal of wastes generated by UGTA Project activities. The objective of this waste management plan is to provide guidelines to minimize waste generation and to properly manage wastes that are produced. Attachment 1 to this plan is the Fluid Management Plan and details specific strategies for management of fluids produced under UGTA operations.

  11. NASA Technology Area 07: Human Exploration Destination Systems Roadmap

    NASA Technical Reports Server (NTRS)

    Kennedy, Kriss J.; Alexander, Leslie; Landis, Rob; Linne, Diane; Mclemore, Carole; Santiago-Maldonado, Edgardo; Brown, David L.

    2011-01-01

    This paper gives an overview of the National Aeronautics and Space Administration (NASA) Office of Chief Technologist (OCT) led Space Technology Roadmap definition efforts. This paper will given an executive summary of the technology area 07 (TA07) Human Exploration Destination Systems (HEDS). These are draft roadmaps being reviewed and updated by the National Research Council. Deep-space human exploration missions will require many game changing technologies to enable safe missions, become more independent, and enable intelligent autonomous operations and take advantage of the local resources to become self-sufficient thereby meeting the goal of sustained human presence in space. Taking advantage of in-situ resources enhances and enables revolutionary robotic and human missions beyond the traditional mission architectures and launch vehicle capabilities. Mobility systems will include in-space flying, surface roving, and Extra-vehicular Activity/Extravehicular Robotics (EVA/EVR) mobility. These push missions will take advantage of sustainability and supportability technologies that will allow mission independence to conduct human mission operations either on or near the Earth, in deep space, in the vicinity of Mars, or on the Martian surface while opening up commercialization opportunities in low Earth orbit (LEO) for research, industrial development, academia, and entertainment space industries. The Human Exploration Destination Systems (HEDS) Technology Area (TA) 7 Team has been chartered by the Office of the Chief Technologist (OCT) to strategically roadmap technology investments that will enable sustained human exploration and support NASA s missions and goals for at least the next 25 years. HEDS technologies will enable a sustained human presence for exploring destinations such as remote sites on Earth and beyond including, but not limited to, LaGrange points, low Earth orbit (LEO), high Earth orbit (HEO), geosynchronous orbit (GEO), the Moon, near

  12. NASA UAS Integration into the NAS Project: Human Systems Integration

    NASA Technical Reports Server (NTRS)

    Shively, Jay

    2016-01-01

    This presentation provides an overview of the work the Human Systems Integration (HSI) sub-project has done on detect and avoid (DAA) displays while working on the UAS (Unmanned Aircraft System) Integration into the NAS project. The most recent simulation on DAA interoperability with Traffic Collision Avoidance System (TCAS) is discussed in the most detail. The relationship of the work to the larger UAS community and next steps are also detailed.

  13. The Human Genome Diversity (HGD) Project. Summary document

    SciTech Connect

    1993-12-31

    In 1991 a group of human geneticists and molecular biologists proposed to the scientific community that a world wide survey be undertaken of variation in the human genome. To aid their considerations, the committee therefore decided to hold a small series of international workshops to explore the major scientific issues involved. The intention was to define a framework for the project which could provide a basis for much wider and more detailed discussion and planning--it was recognized that the successful implementation of the proposed project, which has come to be known as the Human Genome Diversity (HGD) Project, would not only involve scientists but also various national and international non-scientific groups all of which should contribute to the project`s development. The international HGD workshop held in Sardinia in September 1993 was the last in the initial series of planning workshops. As such it not only explored new ground but also pulled together into a more coherent form much of the formal and informal discussion that had taken place in the preceding two years. This report presents the deliberations of the Sardinia workshop within a consideration of the overall development of the HGD Project to date.

  14. All equal-area map projections are created equal, but some are more equal than others

    USGS Publications Warehouse

    Usery, E.L.; Seong, J.C.

    2001-01-01

    High-resolution regional and global raster databases are currently being generated for a variety of environmental and scientific modeling applications. The projection of these data from geographic coordinates to a plane coordinate system is subject to significant areal error. Sources of error include users selecting an inappropriate projection or incorrect parameters for a given projection, algorithmic errors in commercial geographic information system (GIS) software, and errors resulting from the projection of data in the raster format. To assess the latter type of errors, the accuracy of raster projection was analyzed by two methods. First, a set of 12 one-degree by one-degree quadrilaterals placed at various latitudes was projected at several raster resolutions and compared to the projection of a vector representation of the same quadrilaterals. Second, several different raster resolutions of land cover data for Asia were projected and the total areas of 21 land cover categories were tabulated and compared. While equal-area projections are designed to specifically preserve area, the comparison of the results of the one-degree by one-degree quadrilaterals with the common equal area projections (e.g., the Mollweide) indicates a considerable variance in the one-degree area after projection. Similarly, the empirical comparison of land cover areas for Asia among various projections shows that total areas of land cover vary with projection type, raster resolution, and latitude. No single projection is best for all resolutions and all latitudes. While any of the equal-area projections tested are reasonably accurate for most applications with resolutions of eight-kilometer pixels or smaller, significant variances in accuracies appear at larger pixel sizes.

  15. Lowell Area Council on Interlibrary Network Radio Project.

    ERIC Educational Resources Information Center

    Panciers, David J.

    In the fall of 1973, public, school, and college librarians in the Lowell, Massachusetts, area formed the Lowell Area Council on Interlibrary Networks (LACOIN). With a grant from the Library Services and Construction Act, Title III, LACOIN initiated library-sponsored public affairs radio broadcasting for its community. Utilizing the Lowell…

  16. Los Alamos Science: The Human Genome Project. Number 20, 1992

    DOE R&D Accomplishments Database

    Cooper, N. G.; Shea, N. eds.

    1992-01-01

    This document provides a broad overview of the Human Genome Project, with particular emphasis on work being done at Los Alamos. It tries to emphasize the scientific aspects of the project, compared to the more speculative information presented in the popular press. There is a brief introduction to modern genetics, including a review of classic work. There is a broad overview of the Genome Project, describing what the project is, what are some of its major five-year goals, what are major technological challenges ahead of the project, and what can the field of biology, as well as society expect to see as benefits from this project. Specific results on the efforts directed at mapping chromosomes 16 and 5 are discussed. A brief introduction to DNA libraries is presented, bearing in mind that Los Alamos has housed such libraries for many years prior to the Genome Project. Information on efforts to do applied computational work related to the project are discussed, as well as experimental efforts to do rapid DNA sequencing by means of single-molecule detection using applied spectroscopic methods. The article introduces the Los Alamos staff which are working on the Genome Project, and concludes with brief discussions on ethical, legal, and social implications of this work; a brief glimpse of genetics as it may be practiced in the next century; and a glossary of relevant terms.

  17. Los Alamos Science: The Human Genome Project. Number 20, 1992

    SciTech Connect

    Cooper, N G; Shea, N

    1992-01-01

    This article provides a broad overview of the Human Genome Project, with particular emphasis on work being done at Los Alamos. It tries to emphasize the scientific aspects of the project, compared to the more speculative information presented in the popular press. There is a brief introduction to modern genetics, including a review of classic work. There is a broad overview of the Genome Project, describing what the project is, what are some of its major five-year goals, what are major technological challenges ahead of the project, and what can the field of biology, as well as society expect to see as benefits from this project. Specific results on the efforts directed at mapping chromosomes 16 and 5 are discussed. A brief introduction to DNA libraries is presented, bearing in mind that Los Alamos has housed such libraries for many years prior to the Genome Project. Information on efforts to do applied computational work related to the project are discussed, as well as experimental efforts to do rapid DNA sequencing by means of single-molecule detection using applied spectroscopic methods. The article introduces the Los Alamos staff which are working on the Genome Project, and concludes with brief discussions on ethical, legal, and social implications of this work; a brief glimpse of genetics as it may be practiced in the next century; and a glossary of relevant terms.

  18. Tunnelling in Urbanised Areas - Geotechnical Case Studies at Different Project Stages

    NASA Astrophysics Data System (ADS)

    Eder, Stefan; Poscher, Gerhard; Kohl, Bernhard

    Tunnelling in urbanised areas is always a challenge for the client and the contractor as well as for the designers, the engineers, and the geologists. The high demand for space and the disturbance of existing infrastructures by construction measures increasingly forces future infrastructure projects to be carried out underground. At the same time, interferences with human, natural or water resources shall be reduced and noise, dust, as well as site traffic shall be minimised. Quite frequently, politics also come into play. All these factors may lead to pre-determined routes, with ground conditions which may not always be very favourable. This article presents examples of different projects at different stages and emphasizes the importance of engineering geology in the route selection process. The most promising options are routes located in ground, which is not sensitive to settlement and/or water ingress. A longer route in favourable ground conditions is to be given preference over a shorter route in adverse ground conditions. In case of no alternative, the risk of surface settlements and exploding construction costs have to be taken into account. The first project presented is the railway line in the Inn valley / Tyrol, comprising four sections in urbanised areas, which - due to environmental and political reasons - have to cross infrastructure facilities and traffic lines, often in unfavourable ground conditions. There is a variety of construction methods in the tender design to be applied in urbanised tunnelling ranging from NATM tunnels with local groundwater draw-down and jet grouting enclosure against water pressure, to TBM-driven tunnels with hydro-shield. The second project is a planned by-pass for the city of Linz, which is at the environmental impact assessment stage. The alignment is dominated by geological considerations, avoiding unfavourable ground conditions to the greatest possible extent.

  19. A Novel Human Body Area Network for Brain Diseases Analysis.

    PubMed

    Lin, Kai; Xu, Tianlang

    2016-10-01

    Development of wireless sensor and mobile communication technology provide an unprecedented opportunity for realizing smart and interactive healthcare systems. Designing such systems aims to remotely monitor the health and diagnose the diseases for users. In this paper, we design a novel human body area network for brain diseases analysis, which is named BABDA. Considering the brain is one of the most complex organs in the human body, the BABDA system provides four function modules to ensure the high quality of the analysis result, which includes initial data collection, data correction, data transmission and comprehensive data analysis. The performance evaluation conducted in a realistic environment with several criteria shows the availability and practicability of the BABDA system. PMID:27526187

  20. Human impact on the coastal area of Ishem -Shengjin

    NASA Astrophysics Data System (ADS)

    Dollma, Merita

    2010-05-01

    Human impact on the coastal area of Ishem -Shengjin This paper is about the natural and human factors role impact on the geomorphology of the coastal area of Ishem -Shengjin. The morphotectonic and morphologic evolution of this zone is closely connected to the Adriatic sea and Mat, Ishem rivers activities. An important role in this evolution has also played the tectonic faults, where Mat and Ishem rivers flow. River delta advancing in this zone, besides the littoral cordons, is connected to the river solid loads (about 5380 ton/km2), which manage to compensate the continuous tectonic subsidents of its structural basement. The presence of the lagoons (Patok, Merxhan, Ceka), dead meanders and marshlands along a distance of 2-4 km of this zone, are the evidences of continues morphologic evolution of the present coastline, especially between these two rivers. The higher tectonic subsident values of the basement along Mat fault have also defined the smaller size of the alluvial field of this river compare to the alluvial field created by Ishem river. This tectonic phenomena is evidenced with the different thickness of the quaternary depositions along the Ishem river sector (30-80m) and along Mati river (250-290 m). Human impact on the geomorphologic evolution of this zone has caused the total destruction of Patok beach, due to the deviation of the Ishem river flow to the lagoon of Patok. The creation of the artificial reservoirs along Mat river (Ulez, Shkopet) and Ishem river (Bovilla), besides the extraction of the river inert materials along Mati riverbed and destruction of the river banks concretes, have decreased the solid river load. This has caused the beginning of the erosion process of the coastline in some sectors of this zone. Consequently the damages on the natural environment of this zone caused by the human impact are severe and their rehabilitation and management needs an integrated approach from different actors.

  1. Human factors in aviation: Terminal control area boundary conflicts

    NASA Technical Reports Server (NTRS)

    Monan, William P.

    1989-01-01

    Air-to-air conflicts in the vicinity of Terminal Control Area (TCA) boundaries were studied to obtain a better understanding of the causal dynamics of these events with particular focus on human factor issues. The study dataset consisted of 381 Instrument Flight Rules/Visual Flight Rules (IFR/VFR) traffic conflicts in airspace layers above TCA ceiling and below TCA floors; 213 reports of incursions in TCA terminal airspace by VFR aircraft, of which 123 resulted in conflicts; and an additional set of reports describing problems with Air Traffic Control (ATC) services in and around TCAs. Results and conclusions are detailed.

  2. 7 CFR 1450.202 - Project area selection criteria.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM...) The dry tons of renewable biomass projected to be available from sources other than the eligible crops... opportunity for producers and local investors to participate in the ownership of the biomass...

  3. 7 CFR 1450.202 - Project area selection criteria.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM...) The dry tons of renewable biomass projected to be available from sources other than the eligible crops... opportunity for producers and local investors to participate in the ownership of the biomass...

  4. 7 CFR 1450.202 - Project area selection criteria.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM...) The dry tons of renewable biomass projected to be available from sources other than the eligible crops... opportunity for producers and local investors to participate in the ownership of the biomass...

  5. 7 CFR 634.12 - Eligible project areas.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ..., DEPARTMENT OF AGRICULTURE LONG TERM CONTRACTING RURAL CLEAN WATER PROGRAM Project Authorization and Funding... agricultural portion of a 208 water quality management plan, or revised portions thereof, and have identified agricultural nonpoint source water quality problems are eligible for authorization under RCWP. Those...

  6. 7 CFR 634.12 - Eligible project areas.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ..., DEPARTMENT OF AGRICULTURE LONG TERM CONTRACTING RURAL CLEAN WATER PROGRAM Project Authorization and Funding... agricultural portion of a 208 water quality management plan, or revised portions thereof, and have identified agricultural nonpoint source water quality problems are eligible for authorization under RCWP. Those...

  7. 7 CFR 634.12 - Eligible project areas.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ..., DEPARTMENT OF AGRICULTURE LONG TERM CONTRACTING RURAL CLEAN WATER PROGRAM Project Authorization and Funding... agricultural portion of a 208 water quality management plan, or revised portions thereof, and have identified agricultural nonpoint source water quality problems are eligible for authorization under RCWP. Those...

  8. 7 CFR 634.12 - Eligible project areas.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ..., DEPARTMENT OF AGRICULTURE LONG TERM CONTRACTING RURAL CLEAN WATER PROGRAM Project Authorization and Funding... agricultural portion of a 208 water quality management plan, or revised portions thereof, and have identified agricultural nonpoint source water quality problems are eligible for authorization under RCWP. Those...

  9. 7 CFR 634.12 - Eligible project areas.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., DEPARTMENT OF AGRICULTURE LONG TERM CONTRACTING RURAL CLEAN WATER PROGRAM Project Authorization and Funding... agricultural portion of a 208 water quality management plan, or revised portions thereof, and have identified agricultural nonpoint source water quality problems are eligible for authorization under RCWP. Those...

  10. THE MADISON AREA PROJECT--WORLD-OF-WORK PROGRAM.

    ERIC Educational Resources Information Center

    CANGEMI, JOSEPH P.; FANTINI, MARIO D.

    GOALS OF THE PROJECT ARE TO INVESTIGATE AVAILABLE RESEARCH CONCERNING DROPOUTS, TO IDENTIFY POTENTIAL DROPOUTS, TO IDENTIFY PROBLEMS CONNECTED WITH DROPPING OUT OF SCHOOL, TO INCREASE THE SCHOOL-HOLDING POWER, TO EQUIP UNSKILLED STUDENTS WITH SKILLS, TO INCREASE VOCATIONAL, ACADEMIC, SOCIAL, AND COMMUNITY KNOWLEDGE AND INTERESTS, AND TO DEVELOP…

  11. 78 FR 63481 - Therapeutic Area Standards Initiative Project Plan; Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-24

    ... exchange of regulated study data, and (2) issuing a notice in the August 14, 2012 Federal Register (77 FR... process for drugs and biologics. The TA Project Plan will be updated annually and made available for... develop and implement TA standards to support the regulatory review process for drugs and...

  12. 77 FR 5489 - Identification of Human Cell Lines Project

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-03

    ... identification as part of this project will undergo STR profiling, a DNA profiling method that examines/screens for STRs (DNA elements 2-6 bps long repeated in tandem) in the human chromosomes, that has been shown... are expected between cell line DNA samples originating from unrelated individuals. Each unique...

  13. Landscaping Habitat for Humanity Homes: A Community Outreach Project

    ERIC Educational Resources Information Center

    Ramsay, Jodie L.

    2008-01-01

    The purpose of this project is to incorporate a community service component into a Biology course at Northern State University (NSU) in Aberdeen, SD. Students in an upper-level botany course (Plant Structure and Function) provide landscaping services to homeowners who have purchased homes through Habitat for Humanity. Homeowner satisfaction with…

  14. Head of Human Genome Project Retracts 5 Journal Articles.

    ERIC Educational Resources Information Center

    Haworth, Karla

    1996-01-01

    Five published leukemia studies have been retracted by the director of the Human Genome Project because they were based on falsified data from a graduate student, although some of the conclusions are still supported. Inconsistencies were discovered by a peer reviewer and were also found in the student's other work. (MSE)

  15. Enhancing Biology Instruction with the Human Genome Project

    ERIC Educational Resources Information Center

    Buxeda, Rosa J.; Moore-Russo, Deborah A.

    2003-01-01

    The Human Genome Project (HGP) is a recent scientific milestone that has received notable attention. This article shows how a biology course is using the HGP to enhance students' experiences by providing awareness of cutting edge research, with information on new emerging career options, and with opportunities to consider ethical questions raised…

  16. The Human Genome Project: Biology, Computers, and Privacy.

    ERIC Educational Resources Information Center

    Cutter, Mary Ann G.; Drexler, Edward; Gottesman, Kay S.; Goulding, Philip G.; McCullough, Laurence B.; McInerney, Joseph D.; Micikas, Lynda B.; Mural, Richard J.; Murray, Jeffrey C.; Zola, John

    This module, for high school teachers, is the second of two modules about the Human Genome Project (HGP) produced by the Biological Sciences Curriculum Study (BSCS). The first section of this module provides background information for teachers about the structure and objectives of the HGP, aspects of the science and technology that underlie the…

  17. Human Relations Training for Educators. Final Evaluation. Project Upper Cumberland.

    ERIC Educational Resources Information Center

    Khanna, J. L.

    Project Upper Cumberland was a three year endeavor which served 16 Tennessee counties. The final report and evaluation, in three documents, summarizes the three innovative programs which it engendered: (1) teacher inservice training, emphasizing human relations; (2) a pilot cultural arts program (art, music, drama) for grades 1-12; and (3) a pilot…

  18. 77 FR 33774 - Agency Information Collection Activities: Comment Request; Education and Human Resources Project...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-07

    ... Agency Information Collection Activities: Comment Request; Education and Human Resources Project... of Collection: Education and Human Resources Project Monitoring Clearance. OMB Approval Number: 3145... States and internationally. The Directorate for Education and Human Resources (EHR), a unit within...

  19. The Visible Human Project: a resource for education.

    PubMed

    Ackerman, M J

    1999-06-01

    Throughout recorded history, the relationships between biological structure and function have been central to the understanding of health and disease. For many centuries, the anatomy illustrations originally created during the medieval period formed the basis for the study of medicine. But learning and understanding anatomic structures is limited by the fundamentally two-dimensional images traditionally used to teach them. The digital computer now allows scientists to acquire, store, manipulate, and display complex images. In 1989, the National Library of Medicine (NLM) began a project to use computer technologies to build a prototype digital image library of data representing a complete normal adult human male and female. In this paper, the author describes the beginnings of this project, the Visible Human Project (VHP), the digital images currently available in the VHP database, ongoing research and development, and plans for the future of the VHP. PMID:10386094

  20. The implications of the Human Genome Project for family practice.

    PubMed

    Whittaker, L A

    1992-09-01

    The Human Genome Project is an international effort to map and sequence the human genome. The information it will generate has been referred to by some as the "new anatomy," and may play an important role in the future of medicine. However, as with any new technological advancement, the outcome of the Human Genome Project and the subsequent availability of new technology will raise a myriad of ethical, legal, and social concerns. The fear is that this technology will be applied in the clinical setting before the appropriate infrastructure is in place to deal with the issues it will raise. The family physician, far from being merely an interested observer in this process, will be responsible for the delivery of much of this technology as it becomes available. As an intermediary between the technology and the individual patient, the physician has a unique obligation to join in the thoughtful consideration and debate of these issues. PMID:1517727

  1. The WU-Minn Human Connectome Project: An Overview

    PubMed Central

    Smith, Stephen M.; Barch, Deanna M.; Behrens, Timothy E.J.; Yacoub, Essa; Ugurbil, Kamil

    2013-01-01

    The Human Connectome Project consortium led by Washington University, University of Minnesota, and Oxford University is undertaking a systematic effort to map macroscopic human brain circuits and their relationship to behavior in a large population of healthy adults. This overview article focuses on progress made during the first half of the 5-year project in refining the methods for data acquisition and analysis. Preliminary analyses based on a finalized set of acquisition and preprocessing protocols demonstrate the exceptionally high quality of the data from each modality. The first quarterly release of imaging and behavioral data via the ConnectomeDB database demonstrates the commitment to making HCP datasets freely accessible. Altogether, the progress to date provides grounds for optimism that the HCP datasets and associated methods and software will become increasingly valuable resources for characterizing human brain connectivity and function, their relationship to behavior, and their heritability and genetic underpinnings. PMID:23684880

  2. The WU-Minn Human Connectome Project: an overview.

    PubMed

    Van Essen, David C; Smith, Stephen M; Barch, Deanna M; Behrens, Timothy E J; Yacoub, Essa; Ugurbil, Kamil

    2013-10-15

    The Human Connectome Project consortium led by Washington University, University of Minnesota, and Oxford University is undertaking a systematic effort to map macroscopic human brain circuits and their relationship to behavior in a large population of healthy adults. This overview article focuses on progress made during the first half of the 5-year project in refining the methods for data acquisition and analysis. Preliminary analyses based on a finalized set of acquisition and preprocessing protocols demonstrate the exceptionally high quality of the data from each modality. The first quarterly release of imaging and behavioral data via the ConnectomeDB database demonstrates the commitment to making HCP datasets freely accessible. Altogether, the progress to date provides grounds for optimism that the HCP datasets and associated methods and software will become increasingly valuable resources for characterizing human brain connectivity and function, their relationship to behavior, and their heritability and genetic underpinnings. PMID:23684880

  3. Projected Allied Health and Nursing Training Needs for a Seven-County Area in West Virginia.

    ERIC Educational Resources Information Center

    Bertram, Charles L.; And Others

    This report describes a project that developed and field tested a model for projecting state-wide manpower needs in the allied health and nursing occupations in West Virginia and presents projections made for sixteen allied health and nursing occupations in the Charleston area. The content of the report is presented in three sections. The first…

  4. Human cortical areas involved in perception of surface glossiness.

    PubMed

    Wada, Atsushi; Sakano, Yuichi; Ando, Hiroshi

    2014-09-01

    Glossiness is the visual appearance of an object's surface as defined by its surface reflectance properties. Despite its ecological importance, little is known about the neural substrates underlying its perception. In this study, we performed the first human neuroimaging experiments that directly investigated where the processing of glossiness resides in the visual cortex. First, we investigated the cortical regions that were more activated by observing high glossiness compared with low glossiness, where the effects of simple luminance and luminance contrast were dissociated by controlling the illumination conditions (Experiment 1). As cortical regions that may be related to the processing of glossiness, V2, V3, hV4, VO-1, VO-2, collateral sulcus (CoS), LO-1, and V3A/B were identified, which also showed significant correlation with the perceived level of glossiness. This result is consistent with the recent monkey studies that identified selective neural response to glossiness in the ventral visual pathway, except for V3A/B in the dorsal visual pathway, whose involvement in the processing of glossiness could be specific to the human visual system. Second, we investigated the cortical regions that were modulated by selective attention to glossiness (Experiment 2). The visual areas that showed higher activation to attention to glossiness than that to either form or orientation were identified as right hV4, right VO-2, and right V3A/B, which were commonly identified in Experiment 1. The results indicate that these commonly identified visual areas in the human visual cortex may play important roles in glossiness perception. PMID:24825505

  5. City of Huntsville Public Housing Areas STEM Initiative Project

    NASA Astrophysics Data System (ADS)

    Colon, Tomeka; Smith, Cydale; Pugh, Marcus; Budak, Satilmis; Muntele, Claudiu

    2012-02-01

    Students in high-poverty and high-minority schools are entering the classroom without the knowledge and skills they need to succeed. In order to bridge the gaps in opportunity and achievement that separate low-income students and students of color from other young Americans, we have introduced elementary and middle school students to the basic concepts of biology, chemistry, physics, and engineering. Within the project, we have provided students with excellent learning opportunities, engaging hands-on experiences, and outstanding advising and mentoring. We have assessed student development and impact before, during, and after the program.

  6. Alaska Humans Factors Safety Study: The Southern Coastal Area

    NASA Technical Reports Server (NTRS)

    Chappell, Sheryl L.; Reynard, William (Technical Monitor)

    1995-01-01

    At the request of the Alaska Air Carriers Association, researchers from the NASA Aviation Safety Reporting System, at NASA Ames Research Center, conducted a study on aspects of safety in Alaskan Part 135 air taxi operations. An interview form on human factors safety issues was created by a representative team from the FAA-Alaska, NTSB-Alaska, NASA-ASRS, and representatives of the Alaska Air Carriers Association which was subsequently used in the interviews of pilots and managers. Because of the climate and operational differences, the study was broken into two geographical areas, the southern coastal areas and the northern portion of the state. This presentation addresses the southern coastal areas, specifically: Anchorage, Dillingham, King Salmon, Kodiak, Cold Bay, Juneau, and Ketchikan. The interview questions dealt with many of the potential pressures on pilots and managers associated with the daily air taxi operations in Alaska. The impact of the environmental factors such as the lack of available communication, navigation and weather information systems was evaluated. The results of this study will be used by government and industry working in Alaska. These findings will contribute important information on specific Alaska safety issues for eventual incorporation into training materials and policies that will help to assure the safe conduct of air taxi flights in Alaska.

  7. Alaska Humans Factors Safety Study: The Northern Area

    NASA Technical Reports Server (NTRS)

    Connell, Linda; Reynard, William (Technical Monitor)

    1995-01-01

    At the request of the Alaska Air Carriers Association, researchers from the NASA Aviation Safety Reporting System, at NASA Ames Research Center, conducted a study on aspects of safety in Alaskan Part 135 air taxi operations. An interview form on human factors safety issues was created by a representative team from the FAA-Alaska, NTSB-Alaska, NASAASRS, and representatives of the Alaska Air Carriers Association which was subsequently used in the interviews of pilots and managers. Because of the climate and operational differences, the study was broken into two geographical areas, the southern coastal areas and the northern portion of the state. This presentation addresses the northern area, specifically: Bethel, Fairbanks, Nome, Kotzebue, and Barrow. The interview questions dealt with many of the potential pressures on pilots and managers associated with the daily air taxi operations in Alaska. The impact of the environmental factors such as the lack of available communication, navigation and weather information systems was evaluated. The results of this study will be used by government and industry working in Alaska. These findings will contribute important information on specific Alaska safety issues for eventual incorporation into training materials and policies that will help to assure the safe conduct of air taxi flights in Alaska.

  8. Human migration, protected areas, and conservation outreach in Tanzania.

    PubMed

    Salerno, Jonathan D; Borgerhoff Mulder, Monique; Kefauver, Shawn C

    2014-06-01

    A recent discussion debates the extent of human in-migration around protected areas (PAs) in the tropics. One proposed argument is that rural migrants move to bordering areas to access conservation outreach benefits. A counter proposal maintains that PAs have largely negative effects on local populations and that outreach initiatives even if successful present insufficient benefits to drive in-migration. Using data from Tanzania, we examined merits of statistical tests and spatial methods used previously to evaluate migration near PAs and applied hierarchical modeling with appropriate controls for demographic and geographic factors to advance the debate. Areas bordering national parks in Tanzania did not have elevated rates of in-migration. Low baseline population density and high vegetation productivity with low interannual variation rather than conservation outreach explained observed migration patterns. More generally we argue that to produce results of conservation policy significance, analyses must be conducted at appropriate scales, and we caution against use of demographic data without appropriate controls when drawing conclusions about migration dynamics. PMID:24476123

  9. The human proteome project: Current state and future direction.

    PubMed

    Legrain, Pierre; Aebersold, Ruedi; Archakov, Alexander; Bairoch, Amos; Bala, Kumar; Beretta, Laura; Bergeron, John; Borchers, Christoph; Corthals, Garry L; Costello, Catherine E; Deutsch, Eric W; Domon, Bruno; Hancock, William; He, Fuchu; Hochstrasser, Denis; Marko-Varga, Gyorgy; Salekdeh, Ghasem Hosseini; Sechi, Salvatore; Snyder, Michael; Srivastava, Sudhir; Uhlen, Mathias; Hu, Cathy H; Yamamoto, Tadashi; Paik, Young-Ki; Omenn, Gilbert S

    2011-04-29

    After successful completion of the Human Genome Project (HGP), HUPO has recently officially launched a global Human Proteome Project (HPP) which is designed to map the entire human protein set. Given the presence of about 30% undisclosed proteins out of 20,300 protein gene products, a systematic global effort is necessary to achieve this goal with respect to protein abundance, distribution, subcellular localization, interaction with other biomolecules, and functions at specific time points. As a general experimental strategy, HPP groups employ the three working pillars for HPP: mass spectrometry, antibody capture, and bioinformatics tools and knowledge base. The HPP participants will take advantage of the output and cross-analyses from the ongoing HUPO initiatives and a chromosome-based protein mapping strategy, termed C-HPP with many national teams currently engaged. In addition, numerous biologically-driven projects will be stimulated and facilitated by the HPP. Timely planning with proper governance of HPP will deliver a protein parts list, reagents and tools for protein studies and analyses, and a stronger basis for personalized medicine. HUPO urges each national research funding agency and the scientific community at large to identify their preferred pathways to participate in aspects of this highly promising project in a HPP consortium of funders and investigators. PMID:21531903

  10. Projecting crop yield in northern high latitude area.

    PubMed

    Matsumura, Kanichiro

    2014-01-01

    Changing climatic conditions on seasonal and longer time scales influence agricultural production. Improvement of soil and fertilizer is a strong factor in agricultural production, but agricultural production is influenced by climate conditions even in highly developed countries. It is valuable if fewer predictors make it possible to conduct future projections. Monthly temperature and precipitation, wintertime 500hPa geopotential height, and the previous year's yield are used as predictors to forecast spring wheat yield in advance. Canadian small agricultural divisions (SAD) are used for analysis. Each SAD is composed of a collection of Canadian Agricultural Regions (CAR) of similar weather and growing conditions. Spring wheat yields in each CAR are forecast from the following variables: (a) the previous year's yield, (b) earlier stages of the growing season's climate conditions and, (c) the previous year's wintertime northern hemisphere 500hPa geopotential height field. Arctic outflow events in the Okanagan Valley in Canada are associated with episodes of extremely low temperatures during wintertime. Principal component analysis (PCA) is applied for wintertime northern hemisphere 500hPa geopotential height anomalies. The spatial PCA mode1 is defined as Arctic Oscillation and it influences prevailing westerlies. The prevailing westerlies meanders and influences climatic conditions. The spatial similarity between wintertime top 5 Arctic outflow event year's composites of 500hPa geopotential height anomalies and mode 3's spatial pattern is found. Mode 3's spatial pattern looks like the Pacific/North American (PNA) pattern which describes the variation of atmospheric circulation pattern over the Pacific Ocean and North America. Climate conditions from April to June, May to July, mode 3's time coefficients, and previous year's yield are used for forecasting spring wheat yield in each SAD. Cross-validation procedure which generates eight sets of models for the eight

  11. Standard guidelines for the chromosome-centric human proteome project.

    PubMed

    Paik, Young-Ki; Omenn, Gilbert S; Uhlen, Mathias; Hanash, Samir; Marko-Varga, György; Aebersold, Ruedi; Bairoch, Amos; Yamamoto, Tadashi; Legrain, Pierre; Lee, Hyoung-Joo; Na, Keun; Jeong, Seul-Ki; He, Fuchu; Binz, Pierre-Alain; Nishimura, Toshihide; Keown, Paul; Baker, Mark S; Yoo, Jong Shin; Garin, Jerome; Archakov, Alexander; Bergeron, John; Salekdeh, Ghasem Hosseini; Hancock, William S

    2012-04-01

    The objective of the international Chromosome-Centric Human Proteome Project (C-HPP) is to map and annotate all proteins encoded by the genes on each human chromosome. The C-HPP consortium was established to organize a collaborative network among the research teams responsible for protein mapping of individual chromosomes and to identify compelling biological and genetic mechanisms influencing colocated genes and their protein products. The C-HPP aims to foster the development of proteome analysis and integration of the findings from related molecular -omics technology platforms through collaborations among universities, industries, and private research groups. The C-HPP consortium leadership has elicited broad input for standard guidelines to manage these international efforts more efficiently by mobilizing existing resources and collaborative networks. The C-HPP guidelines set out the collaborative consensus of the C-HPP teams, introduce topics associated with experimental approaches, data production, quality control, treatment, and transparency of data, governance of the consortium, and collaborative benefits. A companion approach for the Biology and Disease-Driven HPP (B/D-HPP) component of the Human Proteome Project is currently being organized, building upon the Human Proteome Organization's organ-based and biofluid-based initiatives (www.hupo.org/research). The common application of these guidelines in the participating laboratories is expected to facilitate the goal of a comprehensive analysis of the human proteome. PMID:22443261

  12. Sustaining Jamaica's forests: The protected areas resource conservation project

    NASA Astrophysics Data System (ADS)

    Berke, Philip R.; Beatley, Timothy

    1995-07-01

    This study examines Jamaica's attempt to protect a tropical forest reserve. The biophysical setting, and the types and magnitude of forest development pressures are reviewed. Next, Jamaica's approach to developing new land-use strategies and compatible environmental protection and economic development programs are examined. Finally, the practical and theoretical implications by which institutions can be designed to encourage planning for sustainable development are reviewed. The implications suggest how to provide an appropriate mix of cooperation and market competition, by which people acting in their own interests accomplish socially equitable economic development, while protecting the environment for the benefit of future generations. The experience illustrates that effective long-term protection of natural areas requires the building of local relationships and support, the development of local economic activities supportive of conservation, the defining of clear boundaries, and significant monitoring and enforcement. Long-term protection of the Blue and John Crow mountains, and other important natural areas of Jamaica, will also require the development of a workable and enforceable system of land-use planning for the island, and adjustments to the economic incentive structure so that sustainable, nonextractive uses of natural capital are placed on equal footing with other economic uses (e.g., coffee production).

  13. Assessing Human Impacts on Climate System over Global Urban Areas

    NASA Astrophysics Data System (ADS)

    Jin, M.; Dickinson, R. E.

    2002-12-01

    Urbanization as a form of rapid change in global land cover will contribute to changes of the climate system. Although the climate impacts of urban growth has been studied since the 1950s, it has only been observed through changes of surface air temperature. The past use of remote sensing to look at small areas suggests that such an approach could be very useful on larger scales. However, what is best to observe in such a context and how it might be related to the simulations of global climate models should first be addressed. Recent observations from the MODerate Resolution Imaging Spectroradiometer (MODIS) on the NASA terra satellite can be applied to monitor urban land surface and atmospheric disturbances caused by human activities. Analyzing all of the global urban pixels for land surface skin temperature, albedo, emissivity, land cover, as well as clouds and aerosol properties, we observe that climae is modified over urban areas from the decrease of surface albedo and emissivity, and from the increase of clouds and sulfate aerosol optical depth. The unique strengths of MODIS data (global coverage, fine resolution, simultaneous measurements of various important surface and atmospheric variables) make it possible to investigate all the cities over the globe, and so advance the understanding of what is the range of urbanization effects, what determine these effects, and so suggest how impacts of urban physical processes may be addressed through use of global climate models.

  14. Detection of human taeniases in Tibetan endemic areas, China.

    PubMed

    Li, Tiaoying; Chen, Xingwang; Yanagida, Tetsuya; Wang, Hao; Long, Changping; Sako, Yasuhito; Okamoto, Munehir; Wu, Yunfei; Giraudoux, Patrick; Raoul, Francis; Nkouawa, Agathe; Nakao, Minoru; Craig, Philip S; Ito, Akira

    2013-11-01

    Detection of taeniasis carriers of Taenia solium is essential for control of cysticercosis in humans and pigs. In the current study, we assessed the positive detection rate of a self-detection tool, stool microscopy with direct smear and coproPCR for taeniasis carriers in endemic Tibetan areas of northwest Sichuan. The self-detection tool through questioning about a history of proglottid expulsion within the previous one year showed an overall positive detection rate of more than 80% for Taenia saginata, T. solium and T. asiatica. The positive detection rate was similar for T. saginata and T. solium. In 132 taeniid tapeworm carriers, 68 (51·5%) were detected by microscopy and 92 (69·7%) were diagnosed by coproPCR. A combination of microscopy and coproPCR increased the positive detection rate to 77·3%. There remained 10 cases (7·6%) coproPCR negative but microscopy positive. Due to the high cost and complicated process, coproPCR is required for the identification of Taenia species only when necessary, though it had a significant higher positive detection rate than microscopy. Combined use of self-detection and stool microscopy are recommended in community-based mass screening for taeniases in this Tibetan area or in other situation-similar endemic regions. PMID:23866973

  15. Assessing human rights impacts in corporate development projects

    SciTech Connect

    Salcito, Kendyl; Utzinger, Jürg; Weiss, Mitchell G.; Münch, Anna K.; Singer, Burton H.; Krieger, Gary R.; Wielga, Mark

    2013-09-15

    Human rights impact assessment (HRIA) is a process for systematically identifying, predicting and responding to the potential impact on human rights of a business operation, capital project, government policy or trade agreement. Traditionally, it has been conducted as a desktop exercise to predict the effects of trade agreements and government policies on individuals and communities. In line with a growing call for multinational corporations to ensure they do not violate human rights in their activities, HRIA is increasingly incorporated into the standard suite of corporate development project impact assessments. In this context, the policy world's non-structured, desk-based approaches to HRIA are insufficient. Although a number of corporations have commissioned and conducted HRIA, no broadly accepted and validated assessment tool is currently available. The lack of standardisation has complicated efforts to evaluate the effectiveness of HRIA as a risk mitigation tool, and has caused confusion in the corporate world regarding company duties. Hence, clarification is needed. The objectives of this paper are (i) to describe an HRIA methodology, (ii) to provide a rationale for its components and design, and (iii) to illustrate implementation of HRIA using the methodology in two selected corporate development projects—a uranium mine in Malawi and a tree farm in Tanzania. We found that as a prognostic tool, HRIA could examine potential positive and negative human rights impacts and provide effective recommendations for mitigation. However, longer-term monitoring revealed that recommendations were unevenly implemented, dependent on market conditions and personnel movements. This instability in the approach to human rights suggests a need for on-going monitoring and surveillance. -- Highlights: • We developed a novel methodology for corporate human rights impact assessment. • We piloted the methodology on two corporate projects—a mine and a plantation. • Human

  16. Human genome project: revolutionizing biology through leveraging technology

    NASA Astrophysics Data System (ADS)

    Dahl, Carol A.; Strausberg, Robert L.

    1996-04-01

    The Human Genome Project (HGP) is an international project to develop genetic, physical, and sequence-based maps of the human genome. Since the inception of the HGP it has been clear that substantially improved technology would be required to meet the scientific goals, particularly in order to acquire the complete sequence of the human genome, and that these technologies coupled with the information forthcoming from the project would have a dramatic effect on the way biomedical research is performed in the future. In this paper, we discuss the state-of-the-art for genomic DNA sequencing, technological challenges that remain, and the potential technological paths that could yield substantially improved genomic sequencing technology. The impact of the technology developed from the HGP is broad-reaching and a discussion of other research and medical applications that are leveraging HGP-derived DNA analysis technologies is included. The multidisciplinary approach to the development of new technologies that has been successful for the HGP provides a paradigm for facilitating new genomic approaches toward understanding the biological role of functional elements and systems within the cell, including those encoded within genomic DNA and their molecular products.

  17. A new five-year plan for the U. S. human genome project

    SciTech Connect

    Collins, F. ); Galas, D. )

    1993-10-01

    Progress toward achieving the first set of goals for the genome project appears to be on schedule or, in some instances, even ahead of schedule. Furthermore, technological improvements that could not have been anticipated in 1990 have in some areas changed the scope of the project and allowed more ambitious approaches. Earlier this year, it was therefore decided to update and extend the initial goals to address the scope of genome research beyond the completion of the original 5-year plan. A major purpose of revising the plan is to inform and provide a new guide to all participants in the genome project about the project's goal. To obtain the advice needed to develop the extended goals, NIH and DOE held a series of meetings with a large number of scientists and other interested scholars and representatives of the public, including many who previously had not been direct participants in the genome project. Reports of all these meetings are available from the Office of Communications of the National Center for Human Genome Research (NCHGR) and the Human Genome Management Information System of DOE. Finally, a group of representative advisors from MIH and DOE drafted a set of new, extended goals for presentation to the National Advisory Council for Human Genome Research of NIH and the Health and Environmental Research Advisory Committee of DOE.

  18. TMS reveals a direct influence of spinal projections from human SMAp on precise force production.

    PubMed

    Entakli, Jonathan; Bonnard, Mireille; Chen, Sophie; Berton, Eric; De Graaf, Jozina B

    2014-01-01

    The corticospinal (CS) system plays an important role in fine motor control, especially in precision grip tasks. Although the primary motor cortex (M1) is the main source of the CS projections, other projections have been found, especially from the supplementary motor area proper (SMAp). To study the characteristics of these CS projections from SMAp, we compared muscle responses of an intrinsic hand muscle (FDI) evoked by stimulation of human M1 and SMAp during an isometric static low-force control task. Subjects were instructed to maintain a small cursor on a target force curve by applying a pressure with their right precision grip on a force sensor. Neuronavigated transcranial magnetic stimulation was used to stimulate either left M1 or left SMAp with equal induced electric field values at the defined cortical targets. The results show that the SMAp stimulation evokes reproducible muscle responses with similar latencies and amplitudes as M1 stimulation, and with a clear and significant shorter silent period. These results suggest that (i) CS projections from human SMAp are as rapid and efficient as those from M1, (ii) CS projections from SMAp are directly involved in control of the excitability of spinal motoneurons and (iii) SMAp has a different intracortical inhibitory circuitry. We conclude that human SMAp and M1 both have direct influence on force production during fine manual motor tasks. PMID:24164635

  19. Hanford Area 1990 population and 50-year projections. [Appendix contains computer programming for population projections and graphs showing them by grid areas

    SciTech Connect

    Beck, D.M.; Scott, M.J.; Shindle, S.F.; Napier, B.A.; Thurman, A.G.; Batishko, N.C. ); Davis, M.D. ); Pittenger, D.B. )

    1991-10-01

    The complex and comprehensive safety analysis activities carried out at Hanford for nonreactor nuclear facilities require data from a number of scientific and engineering disciplines. The types of data that are required include data pertaining to current population and population projections. The types of data found in this document include 1990 census totals for residential population within a 50-mile radius of the 100-N, 200, 300, and 400 Area meteorological towers. This document also contains 50-year projections for residential populations within a 50-mile radius of these four meteorological towers. The analysis of population projections indicates that residential population within a 50-mile radius of the four meteorological towers in question will continue to grow through 2040, although at a slower rate each decade. In all cases, the highest growth is projected for the decade ending in the year 2000. The annual growth rate for this period is projected to be 0.646, 0.633, 0.543, and 0.570 in the 100-N, 200, 300, and 400 Areas, respectively. By 2040, these growth rates are projected to drop to 0.082, 0.068, 0.078, 0.078, respectively. 4 refs., 1 figs., 4 tabs.

  20. The lartge-area picosecond photo-detector (LAPPD) project

    NASA Astrophysics Data System (ADS)

    Varner, Gary

    2012-03-01

    The technological revolution that replaced the bulky Cathode Ray Tube with a wide variety of thin, reduced-cost display technologies, has yet to be realized for photosensors. Such a low-cost, robust and flexible photon detector, capable of efficient single photon measurement with good spatial and temporal resolution, would have numerous scientific, medical and industrial applications. To address the significant technological challenges of realizing such a disruptive technology, the Large Area Picosecond Photo-Detector (LAPPD) collaboration was formed, and has been strongly supported by the Department of Energy. This group leverages the inter-disciplinary capabilities and facilities at Argonne National Laboratory, the Berkeley Space Sciences Laboratory (SSL), electronics expertise at the Universities of Chicago and Hawaii, and close work with industrial partners to extend the known technologies. Advances in theory-inspired design and in-situ photocathode characterization during growth, Atomic Layer Deposition (ALD) for revolutionizing micro-channel plate fabrication, and compact, wave-form sampling CMOS ASIC readout of micro striplines are key tools toward realizing a viable LAPPD device. Progress toward a first 8" x 8" demonstrator module will be presented.

  1. Test Area North Pool Stabilization Project: Environmental assessment

    SciTech Connect

    1996-05-01

    The Test Area North (TAN) Pool is located within the fenced TAN facility boundaries on the Idaho National Engineering Laboratory (INEL). The TAN pool stores 344 canisters of core debris from the March, 1979, Three Mile Island (TMI) Unit 2 reactor accident; fuel assemblies from Loss-of-Fluid Tests (LOFT); and Government-owned commercial fuel rods and assemblies. The LOFT and government owned commercial fuel rods and assemblies are hereafter referred to collectively as {open_quotes}commercial fuels{close_quotes} except where distinction between the two is important to the analysis. DOE proposes to remove the canisters of TMI core debris and commercial fuels from the TAN Pool and transfer them to the Idaho Chemical Processing Plant (ICPP) for interim dry storage until an alternate storage location other than at the INEL, or a permanent federal spent nuclear fuel (SNF) repository is available. The TAN Pool would be drained and placed in an industrially and radiologically safe condition for refurbishment or eventual decommissioning. This environmental assessment (EA) identifies and evaluates environmental impacts associated with (1) constructing an Interim Storage System (ISS) at ICPP; (2) removing the TMI and commercial fuels from the pool and transporting them to ICPP for placement in an ISS, and (3) draining and stabilizing the TAN Pool. Miscellaneous hardware would be removed and decontaminated or disposed of in the INEL Radioactive Waste Management Complex (RWMC). This EA also describes the environmental consequences of the no action alternative.

  2. Observed and Projected Climate Extremities in Chennai Metropolitan Area

    NASA Astrophysics Data System (ADS)

    Anushiya, j.; Andimuthu, R.

    2013-12-01

    Analyses of observed climate throughout world revealed some significant changes in the extremes. Any change in the frequency or severity of extreme climate events would have profound impacts on the resilience of nature and society. It is thus very important to analyze extreme events to reliably monitor and detect climate change. Chennai is the fourth largest metropolis in India and one of the fastest growing economic and Industrial growth centers in South Asia. Population has grown rapidly in the last 20 years due to its major industrialization and tremendous growth. Already Chennai's day and night time Temperature shows an increasing trend. The past incidence of catastrophic flooding was observed in the city due to heavy rains associated with depressions and cyclonic storm lead floods in major rivers. After 2000, the incidents were reported repeatedly. The effort has made in this study to find the observed climate extremities over the past years and in the future. For observed changes, IMD gridded data set, and station data are used. Future high resolution climate scenarios (0.220x0.220) are developed through RCM using PRECIS. The boundary data have provided by the UK Met office. The selected members are simulated under the A1B scenario (a mid range emission scenario) for a continuous run till 2100. Climate indices listed by Expert Team (ET) on Climate Change Detection and Indices (ETCCDI) by the CLIVAR are considered in this study. The indices were obtained using the software package RClimDex. Kendall's tau based slope estimator has been used to find the significance lavel. The results shows the significant increasing tendency of warm days (TX90P) in the past and in future. The trends in extreme wet days (R99P) are also increased. The growth in population, urban and industrial area, economic activities, depletion of natural resources along with changing climate are forced to develop the infrastructure includes climate friendly policies to adopt and to ensure the

  3. Linking with Community To Reclaim Natural Areas for Education: The McLane Elementary School Project.

    ERIC Educational Resources Information Center

    Spencer, Melinda; Smith, Kathy Kurtz

    2002-01-01

    Describes a project in which students, teachers, and the community work to reclaim neglected wetlands and forested areas for use as an environmental study site for interdisciplinary learning. (Author/MM)

  4. 7. Photocopy of engineering drawing. PROJECT WS315A HELIUM STORAGE AREA: ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Photocopy of engineering drawing. PROJECT WS-315A HELIUM STORAGE AREA: PLAN AND DETAILS-MECHANICAL, APRIL 1956. - Cape Canaveral Air Station, Launch Complex 17, Facility 28419, East end of Lighthouse Road, Cape Canaveral, Brevard County, FL

  5. The projection of the primary somatic sensory cortex upon area 5 in the monkey.

    PubMed

    Pearson, R C; Powell, T P

    1985-04-01

    The projection of the cortex of the primary somatic sensory area (S1) upon area 5 in the rhesus monkey has been studied with axonal degeneration methods. There is little or no overlap between the major topographic representations in area 5 but there is both convergence and divergence within a representation; the degeneration after a small lesion in a representation in SI virtually fills the representation in area 5 and there is extensive overlap of the degeneration after two lesions in widely separated parts of the representation in S1. The representation of the arm in area 5 is surprisingly large, that of the face is relatively smaller than in S1 and the trunk and leg are about the same as in S1. Lesions in the trunk and face representations result in terminal degeneration throughout the antero-posterior extent of area 5, but after damage of the limb representations the degeneration in area 5 is concentrated into 3 medio-laterally disposed bands. Of the cytoarchitectonic subdivisions of S1, area 2 projects most heavily upon area 5 and area 3b the least, and there is a reversal in the antero-posterior dimension with more posterior parts of S1 projecting to more anterior parts of area 5. The corticocortical fibres from S1 end in layers III and IV of area 5, and while the degeneration in layer IV is continuous it is in distinct 'prongs' in layer III. PMID:3995356

  6. Fluid Management Plan for Corrective Action Unit 447: Project Shoal Area, Subsurface, Nevada, Rev. No.: 1

    SciTech Connect

    Findlay, Rick

    2006-01-01

    The U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office (NNSA/NSO) initiated the Offsites Project to characterize the risk posed to human health and the environment as a result of testing at formerly used nuclear sites in Alaska, Colorado, Mississippi, Nevada, and New Mexico. The scope of this Fluid Management Plan (FMP) is to support the subsurface investigation at the Project Shoal Area (PSA) Corrective Action Unit (CAU) 447, Shoal - Subsurface, Nevada, in accordance with the ''Federal Facility Agreement and Consent Order'' (FFACO) (1996). Corrective Action Unit 447 is located in the Sand Spring Range, south of Highway 50, about 39 miles southeast of Fallon, Nevada. (Figure 1-1). This FMP will be used at the PSA in lieu of an individual discharge permit for each well or a general water pollution control permit for management of all fluids produced during the drilling, construction, development, testing, experimentation, and/or sampling of wells conducted by the Offsites Project. The FMP provides guidance for the management of fluids generated during investigation activities and provides the standards by which fluids may be discharged on site. Although the Nevada Division of Environmental Protection (NDEP), Bureau of Federal Facilities (BoFF) is not a signatory to this FMP, it is involved in the negotiation of the contents of this plan and approves the conditions contained within. The major elements of this FMP include: (1) establishment of a well-site operations strategy; (2) site design/layout; (3) monitoring of contamination indicators (monitoring program); (4) sump characterization (sump sampling program); (5) fluid management decision criteria and fluid disposition; and (6) reporting requirements.

  7. Research, demonstration, and extension: the ARS area-wide ecologically based invasive plant management project

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The Area-wide project is a collaborative five year effort funded in 2008 by USDA-ARS that has brought together scientists with the USDA-ARS, universities, land managers, and policy makers throughout the Great Basin. A primary goal of the project is to develop and implement a comprehensive, regional...

  8. Rural Critical Care Nurse Training Project--Four Corners Area, November 14, 1975.

    ERIC Educational Resources Information Center

    New Mexico Regional Medical Program, Albuquerque.

    Project objectives were to train 10 nurses from hospitals in the Four Corners Area in rural critical care nursing, to have a training director organize and coordinate the project, and to utilize the replacement nurse concept. The course curriculum was determined through a needs assessment survey conducted by a team of health professionals from…

  9. Area Fish and Game Ecology [Sahuarita High School Career Curriculum Project.

    ERIC Educational Resources Information Center

    Esser, Robert

    This course entitled "Area Fish and Game Ecology" is one of a series of instructional guides prepared by teachers for the Sahuarita High School (Arizona) Career Curriculum Project. It consists of nine units of study, and 18 behavioral objectives relating to these units are stated. The topics covered include map projections, map symbols and…

  10. USDA area-wide project for annual grasses: outcomes and impacts

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This document provides a record of the research, outreach, education and technology transfer that was completed as part of the area-wide project for invasive annual grasses from 2007-2012. The overall goal of the project was to catalyze a holistic integrated management program for invasive annual g...

  11. The software analysis project for the Office of Human Resources

    NASA Technical Reports Server (NTRS)

    Tureman, Robert L., Jr.

    1994-01-01

    There were two major sections of the project for the Office of Human Resources (OHR). The first section was to conduct a planning study to analyze software use with the goal of recommending software purchases and determining whether the need exists for a file server. The second section was analysis and distribution planning for retirement planning computer program entitled VISION provided by NASA Headquarters. The software planning study was developed to help OHR analyze the current administrative desktop computing environment and make decisions regarding software acquisition and implementation. There were three major areas addressed by the study: current environment new software requirements, and strategies regarding the implementation of a server in the Office. To gather data on current environment, employees were surveyed and an inventory of computers were produced. The surveys were compiled and analyzed by the ASEE fellow with interpretation help by OHR staff. New software requirements represented a compilation and analysis of the surveyed requests of OHR personnel. Finally, the information on the use of a server represents research done by the ASEE fellow and analysis of survey data to determine software requirements for a server. This included selection of a methodology to estimate the number of copies of each software program required given current use and estimated growth. The report presents the results of the computing survey, a description of the current computing environment, recommenations for changes in the computing environment, current software needs, management advantages of using a server, and management considerations in the implementation of a server. In addition, detailed specifications were presented for the hardware and software recommendations to offer a complete picture to OHR management. The retirement planning computer program available to NASA employees will aid in long-range retirement planning. The intended audience is the NASA civil

  12. From data to knowledge--the Visible Human Project continues.

    PubMed

    Ackerman, M J; Yoo, T; Jenkins, D

    2001-01-01

    The U. S. National Library of Medicine (NLM) has long been a world leader in the archiving and distribution of the print-based images of biology and medicine. NLM has also been a pioneer in the use of computer systems to encode and distribute textual knowledge of the life sciences. NLM's Long Range Planning effort of 1985-86 foresaw a coming era where NLM's Bibliographic and factual database services would be complemented by libraries of digital images, distributed over high speed computer networks. The NLM Planning Panel on Electronic Imaging recommended that NLM should undertake the building a digital image library consisting of computerized tomography (CT) and magnetic resonance (MR) images, and cryosection images of a representative, carefully selected and prepared male and female cadaver--the "Visible Human Project ." The male and female Visible Human data sets are now being made available through a license agreement with the NLM. The data sets are supporting a wide range of educational, diagnostic, treatment planning, and commercial uses. The NLM, in partnership with other U.S. government research agencies has begun a three prong effort within the Visible Human Project to address: the creation of a new online, interactive, digital head-and-neck atlas; the development of a tool kit of computational programs capable of automatically performing many of the basic data handling functions required for using Visible Human data in applications; and the improved resolution of future Visible Human data sets through the reduction of the anatomical artifacts introduced by the methods used to stabilize and section the anatomical materials and the development of staining and wide-spectrum methods for increasing tissue contrast. PMID:11604860

  13. [Human African trypanosomiasis in an urban area: an emerging problem?].

    PubMed

    Louis, F J; Bilenge, C M; Simarro, P P; Meso, V Kande; Lucas, P; Jannin, J

    2003-08-01

    The human African trypanosomiasis is essentially a rural disease. The notification of cases in urban area has always been incidental; either a diagnosis made in town revealed a disease contracted in rural environment or it meant the preservation of a complete epidemiological cycle in a remaining urban micro-focus. In Kinshasa, in Democratic Republic of Congo, about forty cases have been notified each year. All of them came from the nearby foci of Bandundu, Lower Congo and Kasaï. In 1996 the number of cases reached suddenly 254 and today the average annual number comes up to 500 in spite of all the efforts undertaken to fight the disease. A study of cases in 1998 and 1999 shows that patients are essentially distributed in suburbs and that the most affected by the disease are the 15-49 year old ones whose job is related with agricultural or fishing activities. Two phenomena seem to explain this sudden increase: the massive inflow of refugees in outskirts of town coming from provinces where trypanosomiasis is endemic and a major economic crisis throwing out urban population in suburbs living on a subsistence micro-agriculture. These concomitant factors have contributed to the setting up of a trypanosomiasis belt around the capital. Today a strategy has to be reconsidered in order to fight against the disease in the capital itself and to make the medical staff aware of the diagnosis of a disease still unknown in their sanitary district. PMID:14582296

  14. 76 FR 64083 - Loveland Area Projects-2025 Power Marketing Initiative Proposal

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-17

    ... Register (51 FR 4012, January 31, 1986) and provided the marketing plan principles used to market what is...) Final Rule published in the Federal Register (60 FR 54151, October 20, 1995), Subpart C extended and... Area Power Administration Loveland Area Projects--2025 Power Marketing Initiative Proposal...

  15. Communicating Astronomy in a Metropolis and Disaster Area - Activities of the Tenpla Project

    NASA Astrophysics Data System (ADS)

    Kamegai, K.; Takanashi, N.; Hiramatsu, M.; Naito, S.

    2015-03-01

    We present recent activities delivering astronomy to the public by the Tenpla project in Japan. One is voluntary activities in the disaster area of the Great East Japan Earthquake. The other is holding tens of star parties and public lectures in the central area of Tokyo.

  16. PCAP Project Profiles and General Profiles. Priority Country Area Program--Queensland.

    ERIC Educational Resources Information Center

    Priority Country Area Program Office, Brisbane (Australia).

    Four Priority Country Area overviews, one State overview and one Project Profile are included in this report from the Priority Country Area Program (PCAP), designed to improve the educational opportunities of rural Queensland children. The program resulted from a 1977-79 Schools Commission report suggesting that rural students may be disadvantaged…

  17. The human genome project: Prospects and implications for clinical medicine

    SciTech Connect

    Green, E.D.; Waterston, R.H. )

    1991-10-09

    The recently initiated human genome project is a large international effort to elucidate the genetic architecture of the genomes of man and several model organisms. The initial phases of this endeavor involve the establishment of rough blueprints (maps) of the genetic landscape of these genomes, with the long-term goal of determining their precise nucleotide sequences and identifying the genes. The knowledge gained by these studies will provide a vital tool for the study of many biologic processes and will have a profound impact on clinical medicine.

  18. Underground Test Area Quality Assurance Project Plan Nevada National Security Site, Nevada, Revision 0

    SciTech Connect

    Irene Farnham

    2011-05-01

    This Quality Assurance Project Plan (QAPP) provides the overall quality assurance (QA) program requirements and general quality practices to be applied to the U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office (NNSA/NSO) Underground Test Area (UGTA) Sub-Project (hereafter the Sub-Project) activities. The requirements in this QAPP are consistent with DOE Order 414.1C, Quality Assurance (DOE, 2005); U.S. Environmental Protection Agency (EPA) Guidance for Quality Assurance Project Plans for Modeling (EPA, 2002); and EPA Guidance on the Development, Evaluation, and Application of Environmental Models (EPA, 2009). The QAPP Revision 0 supersedes DOE--341, Underground Test Area Quality Assurance Project Plan, Nevada Test Site, Nevada, Revision 4.

  19. Corrective action investigation plan for Project Shoal Area CAU No. 416

    SciTech Connect

    1996-08-01

    This Corrective Action Investigation Plan (CAIP) is part of an ongoing US Department of Energy (DOE)-funded project for the investigation of Corrective Action Unit (CAU) No. 416, Project Shoal Area (PSA). Project Shoal was conducted to determine whether seismic waves produced by underground nuclear testing could be differentiated from naturally occurring earthquakes. The PSA site is located approximately 30 miles southeast of Fallon, Nevada, in the northern portion of Sand Springs Mountains in Churchill County. This CAIP will be implemented in accordance with the Federal Facility Agreement and Consent Order, the Industrial Sites Quality Assurance Project Plan, and all applicable Nevada Division of Environmental Protection policies and regulations.

  20. EGASP: the human ENCODE Genome Annotation Assessment Project

    PubMed Central

    Guigó, Roderic; Flicek, Paul; Abril, Josep F; Reymond, Alexandre; Lagarde, Julien; Denoeud, France; Antonarakis, Stylianos; Ashburner, Michael; Bajic, Vladimir B; Birney, Ewan; Castelo, Robert; Eyras, Eduardo; Ucla, Catherine; Gingeras, Thomas R; Harrow, Jennifer; Hubbard, Tim; Lewis, Suzanna E; Reese, Martin G

    2006-01-01

    Background We present the results of EGASP, a community experiment to assess the state-of-the-art in genome annotation within the ENCODE regions, which span 1% of the human genome sequence. The experiment had two major goals: the assessment of the accuracy of computational methods to predict protein coding genes; and the overall assessment of the completeness of the current human genome annotations as represented in the ENCODE regions. For the computational prediction assessment, eighteen groups contributed gene predictions. We evaluated these submissions against each other based on a 'reference set' of annotations generated as part of the GENCODE project. These annotations were not available to the prediction groups prior to the submission deadline, so that their predictions were blind and an external advisory committee could perform a fair assessment. Results The best methods had at least one gene transcript correctly predicted for close to 70% of the annotated genes. Nevertheless, the multiple transcript accuracy, taking into account alternative splicing, reached only approximately 40% to 50% accuracy. At the coding nucleotide level, the best programs reached an accuracy of 90% in both sensitivity and specificity. Programs relying on mRNA and protein sequences were the most accurate in reproducing the manually curated annotations. Experimental validation shows that only a very small percentage (3.2%) of the selected 221 computationally predicted exons outside of the existing annotation could be verified. Conclusion This is the first such experiment in human DNA, and we have followed the standards established in a similar experiment, GASP1, in Drosophila melanogaster. We believe the results presented here contribute to the value of ongoing large-scale annotation projects and should guide further experimental methods when being scaled up to the entire human genome sequence. PMID:16925836

  1. Technology reinvestment project`s focus area: Electric and hybrid tactical and commercial vehicles

    SciTech Connect

    1994-11-01

    The publication contains the transparencies from the Technology Reinvestment Projects`s (TRP`s) workshops held in Chicago, IL and Austin, TX in November, 1994. It includes general sessions on TRP, Technology Development, Regional Technology Alliances, and Manufacturing Education and Training, as well as the break out session on Electric and Hybrid Tactical and Commercial Vehicles. Also included are registration forms for both workshops.

  2. Bear Creek Valley characterization area mixed wastes passive in situ treatment technology demonstration project - status report

    SciTech Connect

    Watson, D.; Leavitt, M.; Moss, D.

    1997-03-01

    Historical waste disposal activities within the Bear Creek Valley (BCV) Characterization Area (CA), at the U.S. Department of Energy (DOE) Oak Ridge Y-12 plant, have contaminated groundwater and surface water above human health risk levels and impacted the ecology of Bear Creek. Contaminates include nitrate, radioisotopes, metals, volatile organic chemicals (VOCS), and common ions. This paper provides a status report on a technology demonstration project that is investigating the feasibility of using passive in situ treatment systems to remove these contaminants. Although this technology may be applicable to many locations at the Oak Ridge Y-12 Plant, the project focuses on collecting the information needed to take CERCLA removal actions in 1998 at the S-3 Disposal Ponds site. Phase 1 has been completed and included site characterization, laboratory screening of treatment media (sorbents; and iron), and limited field testing of biological treatment systems. Batch tests using different Y-12 Plant waters were conducted to evaluate the removal efficiencies of most of the media. Phase 1 results suggest that the most promising treatment media are Dowex 21 k resin, peat moss, zero-valent iron, and iron oxides. Phase 2 will include in-field column testing of these media to assess loading rates, and concerns with clogging, by-products, and long-term treatment efficiency and media stability. Continued testing of wetlands and algal mats (MATs) will be conducted to determine if they can be used for in-stream polishing of surface water. Hydraulic testing of a shallow trench and horizontal well will also be completed during Phase 2. 4 refs., 3 tabs.

  3. A central mesencephalic reticular formation projection to the supraoculomotor area in macaque monkeys.

    PubMed

    Bohlen, Martin O; Warren, Susan; May, Paul J

    2016-05-01

    The central mesencephalic reticular formation is physiologically implicated in oculomotor function and anatomically interwoven with many parts of the oculomotor system's premotor circuitry. This study in Macaca fascicularis monkeys investigates the pattern of central mesencephalic reticular formation projections to the area in and around the extraocular motor nuclei, with special emphasis on the supraoculomotor area. It also examines the location of the cells responsible for this projection. Injections of biotinylated dextran amine were stereotaxically placed within the central mesencephalic reticular formation to anterogradely label axons and terminals. These revealed bilateral terminal fields in the supraoculomotor area. In addition, dense terminations were found in both the preganglionic Edinger-Westphal nuclei. The dense terminations just dorsal to the oculomotor nucleus overlap with the location of the C-group medial rectus motoneurons projecting to multiply innervated muscle fibers suggesting they may be targeted. Minor terminal fields were observed bilaterally within the borders of the oculomotor and abducens nuclei. Injections including the supraoculomotor area and oculomotor nucleus retrogradely labeled a tight band of neurons crossing the central third of the central mesencephalic reticular formation at all rostrocaudal levels, indicating a subregion of the nucleus provides this projection. Thus, these experiments reveal that a subregion of the central mesencephalic reticular formation may directly project to motoneurons in the oculomotor and abducens nuclei, as well as to preganglionic neurons controlling the tone of intraocular muscles. This pattern of projections suggests an as yet undetermined role in regulating the near triad. PMID:25859632

  4. Projections from the mesopontine tegmental anesthesia area to regions involved in pain modulation.

    PubMed

    Sukhotinsky, I; Reiner, K; Govrin-Lippmann, R; Belenky, M; Lu, J; Hopkins, D A; Saper, C B; Devor, M

    2006-12-01

    Pentobarbital microinjected into a restricted locus in the upper brainstem induces a general anesthesia-like state characterized by atonia, loss of consciousness, and pain suppression as assessed by loss of nocifensive response to noxious stimuli. This locus is the mesopontine tegmental anesthesia area (MPTA). Although anesthetic agents directly influence spinal cord nociceptive processing, antinociception during intracerebral microinjection indicates that they can also act supraspinally. Using neuroanatomical tracing methods we show that the MPTA has multiple descending projections to brainstem and spinal areas associated with pain modulation. Most prominent is a massive projection to the rostromedial medulla, a nodal region for descending pain modulation. Together with the periaqueductal gray (PAG), the MPTA is the major mesopontine input to this region. Less dense projections target the PAG, the locus coeruleus and pericoerulear areas, and dorsal and ventral reticular nuclei of the caudal medulla. The MPTA also has modest direct projections to the trigeminal nuclear complex and to superficial layers of the dorsal horn. Double anterograde and retrograde labeling at the light and electron microscopic levels shows that MPTA neurons with descending projections synapse directly on spinally projecting cells of rostromedial medulla. The prominence of the MPTA's projection to the rostromedial medulla suggests that, like the PAG, it may exert antinociceptive actions via this bulbospinal relay. PMID:17049433

  5. Surface area and cortical thickness descriptors reveal different attributes of the structural human brain networks.

    PubMed

    Sanabria-Diaz, Gretel; Melie-García, Lester; Iturria-Medina, Yasser; Alemán-Gómez, Yasser; Hernández-González, Gertrudis; Valdés-Urrutia, Lourdes; Galán, Lídice; Valdés-Sosa, Pedro

    2010-05-01

    Recently, a related morphometry-based connection concept has been introduced using local mean cortical thickness and volume to study the underlying complex architecture of the brain networks. In this article, the surface area is employed as a morphometric descriptor to study the concurrent changes between brain structures and to build binarized connectivity graphs. The statistical similarity in surface area between pair of regions was measured by computing the partial correlation coefficient across 186 normal subjects of the Cuban Human Brain Mapping Project. We demonstrated that connectivity matrices obtained follow a small-world behavior for two different parcellations of the brain gray matter. The properties of the connectivity matrices were compared to the matrices obtained using the mean cortical thickness for the same cortical parcellations. The topology of the cortical thickness and surface area networks were statistically different, demonstrating that both capture distinct properties of the interaction or different aspects of the same interaction (mechanical, anatomical, chemical, etc.) between brain structures. This finding could be explained by the fact that each descriptor is driven by distinct cellular mechanisms as result of a distinct genetic origin. To our knowledge, this is the first time that surface area is used to study the morphological connectivity of brain networks. PMID:20083210

  6. The human studies database project: federating human studies design data using the ontology of clinical research.

    PubMed

    Sim, Ida; Carini, Simona; Tu, Samson; Wynden, Rob; Pollock, Brad H; Mollah, Shamim A; Gabriel, Davera; Hagler, Herbert K; Scheuermann, Richard H; Lehmann, Harold P; Wittkowski, Knut M; Nahm, Meredith; Bakken, Suzanne

    2010-01-01

    Human studies, encompassing interventional and observational studies, are the most important source of evidence for advancing our understanding of health, disease, and treatment options. To promote discovery, the design and results of these studies should be made machine-readable for large-scale data mining, synthesis, and re-analysis. The Human Studies Database Project aims to define and implement an informatics infrastructure for institutions to share the design of their human studies. We have developed the Ontology of Clinical Research (OCRe) to model study features such as design type, interventions, and outcomes to support scientific query and analysis. We are using OCRe as the reference semantics for federated data sharing of human studies over caGrid, and are piloting this implementation with several Clinical and Translational Science Award (CTSA) institutions. PMID:21347149

  7. Catchment Area Treatment (CAT) Plan and Crop Area Optimization for Integrated Management in a Water Resource Project

    NASA Astrophysics Data System (ADS)

    Jaiswal, R. K.; Thomas, T.; Galkate, R. V.; Ghosh, N. C.; Singh, S.

    2013-09-01

    A scientifically developed catchment area treatment (CAT) plan and optimized pattern of crop areas may be the key for sustainable development of water resource, profitability in agriculture and improvement of overall economy in drought affected Bundelkhand region of Madhya Pradesh (India). In this study, an attempt has been made to develop a CAT plan using spatial variation of geology, geomorphology, soil, drainage, land use in geographical information system for selection of soil and water conservation measures and crop area optimization using linear programming for maximization of return considering water availability, area affinity, fertilizers, social and market constraints in Benisagar reservoir project of Chhatarpur district (M.P.). The scientifically developed CAT plan based on overlaying of spatial information consists of 58 mechanical measure (49 boulder bunds, 1 check dam, 7 cully plug and 1 percolation tank), 2.60 km2 land for agro forestry, 2.08 km2 land for afforestation in Benisagar dam and 67 mechanical measures (45 boulder bunds and 22 gully plugs), 7.79 km2 land for agro forestry, 5.24 km2 land for afforestation in Beniganj weir catchment with various agronomic measures for agriculture areas. The linear programming has been used for optimization of crop areas in Benisagar command for sustainable development considering various scenarios of water availability, efficiencies, affinity and fertilizers availability in the command. Considering present supply condition of water, fertilizers, area affinity and making command self sufficient in most of crops, the net benefit can be increase to Rs. 1.93 crores from 41.70 km2 irrigable area in Benisagar command by optimizing cropping pattern and reducing losses during conveyance and application of water.

  8. Tuberculosis in cattle: the results of the four-area project

    PubMed Central

    2005-01-01

    The four-area project was undertaken to further assess the impact of badger removal on the control of tuberculosis in cattle herds in Ireland. It was conducted between 1997 and 2002 in matched removal and reference areas in four counties, namely Cork, Donegal, Kilkenny and Monaghan, representing a wide range of Irish farming environments. In the removal areas, a proactive programme of badger removal was conducted, on two or three occasions each year, whereas in the reference areas, badger removal was entirely reactive following severe outbreaks of tuberculosis amongst cattle. A detailed statistical analysis of this study has already been presented by Griffin et al. [13]; this paper presents further, mainly descriptive, findings from the study. In total, 2,360 badgers were captured in the removal areas of which 450 (19.5%) were considered positive for tuberculosis and 258 badgers were captured in the reference areas, with 57 (26.1%) positive for tuberculosis. The annual incidence of confirmed herd restrictions was lower in the removal area compared to the reference area in every year of the study period in each of the four counties. These empirical findings were consistent with the hazard ratios found by Griffin et al. [13]. Further, the effect of proactive badger removal on cattle tuberculosis in the four-area project and in the earlier east-Offaly project, as measured using the number of reactors per 1,000 cattle tested, were very similar, providing compelling evidence of the role of badgers in the epidemiology of tuberculosis in Irish cattle herds. The validity of the four-area project was discussed in detail. Efforts to minimise badger-to-cattle transmission in Ireland must be undertaken in association with the current comprehensive control programme, which has effectively minimised opportunities for cattle-to-cattle transmission. PMID:21851665

  9. Adding dynamics to the Human Connectome Project with MEG

    PubMed Central

    Larson-Prior, L. J.; Oostenveld, R.; Della Penna, S.; Michalareas, G.; Prior, F.; Babajani-Feremi, A.; Schoffelen, J-M.; Marzetti, L.; de Pasquale, F.; Di Pompeo, F.; Stout, J.; Woolrich, M.; Luo, Q.; Bucholz, R.; Fries, P.; Pizzella, V.; Romani, G.L.; Corbetta, M.; Snyder, A. Z.

    2013-01-01

    The Human Connectome Project (HCP) seeks to map the structural and functional connections between network elements in the human brain. Magnetoencephalography (MEG) provides a temporally rich source of information on brain network dynamics and represents one source of functional connectivity data to be provided by the HCP. High quality MEG data will be collected from 50 twin pairs both in the resting state and during performance of motor, working memory and language tasks. These data will be available to the general community. Additionally, using the cortical parcellation scheme common to all imaging modalities, the HCP will provide processing pipelines for calculating connection matrices as a function of time and frequency. Together with structural and functional data generated using magnetic resonance imaging methods, these data represent a unique opportunity to investigate brain network connectivity in a large cohort of normal adult human subjects. The analysis pipeline software and the dynamic connectivity matrices that it generates will all be made freely available to the research community. PMID:23702419

  10. Removal Action Plan for the Accelerated Retrieval Project for a Described Area within Pit 4

    SciTech Connect

    A. M. Tyson

    2006-08-01

    This Removal Action Plan documents the plan for implementation of the Comprehensive Environmental Response, Compenstion, and Liability Act non-time-critical removal action to be performed by the Accelerated Retrieval Project. The focus of the action is the limited excavation and retrieval of selected waste streams from a designated portion of the Radioactive Waste Management Complex Subsurface Disposal Area that are contaminated with volatile organic compounds, isotopes of uranium, or transuranic radionuclides. The selected retrieval area is approximately 0.2 ha (1/2 acre) and is located in the eastern portion of Pit 4. The proposed project is referred to as the Accelerated Retrieval Project. This Removal Action Plan details the major work elements, operations approach, and schedule, and summarizes the environmental, safety and health, and waste management considerations associated with the project.

  11. B-Vitamin Levels in Human Milk among Different Lactation Stages and Areas in China

    PubMed Central

    Ren, Xiangnan; Yang, Zhenyu; Shao, Bing; Yin, Shi-an; Yang, Xiaoguang

    2015-01-01

    To determine the contents of B-vitamins in human milk in China, we analyzed 1778 human milk samples from the sample bank of the National High Technique R & D Program (863 Projects) which was a cross-sectional survey and covered 6419 human milk samples from healthy lactating mothers who were at different stages of lactation (0–330 days postpartum) in 11 provinces of China. The contents of free forms of six B-vitamins in these human milk samples were analyzed by using UPLC-MS/MS. The median concentrations of free form of 6 B-vitamins in colostrums, transitional milk, 15–180 d mature milk and 181-330 d mature milk were respectively as follows: thiamin 5.0 µg/L, 6.7 µg/L, 21.1 µg/L and 40.7 µg/L; riboflavin 29.3 µg/L, 40.6 µg/L, 33.6 µg/L and 29.6 µg/L; niacin 470.7 µg/L, 661.3 µg/L, 687.0 µg/L and 571.3 µg/L; vitamin B-6 4.6 µg/L, 16.1 µg/L, 62.7 µg/L and 80.7 µg/L; flavin adenine dinucleotide (FAD) 808.7 µg/L, 1162.8 µg/L, 1023.9 µg/L and 1057.2 µg/L; pantothenic acid 1770.9 µg/L, 2626.8 µg/L, 2213.0 µg/L and 1895.5 µg/L. The contents of 6 B-vitamins varied significantly among the different lactation stages and different areas (coastal area vs inland area, rural area vs urban area). The present study indicated that the concentrations of B-vitamins in colostrum were generally much lower than those in transitional milk and mature milk. Further studies are warranted for their roles and significance on B-vitamins in colostrum in nutrition and metabolism of neonates. PMID:26186707

  12. Rainwater Wildlife Area, Watershed Management Plan, A Columbia Basin Wildlife Mitigation Project, 2002.

    SciTech Connect

    Childs, Allen B.

    2002-03-01

    This Management Plan has been developed by the Confederated Tribes of the Umatilla Indian Reservation (CTUIR) to document how the Rainwater Wildlife Area (formerly known as the Rainwater Ranch) will be managed. The plan has been developed under a standardized planning process developed by the Bonneville Power Administration (BPA) for Columbia River Basin Wildlife Mitigation Projects (See Appendix A and Guiding Policies Section below). The plan outlines the framework for managing the project area, provides an assessment of existing conditions and key resource issues, and presents an array of habitat management and enhancement strategies. The plan culminates into a 5-Year Action Plan that will focus our management actions and prioritize funding during the Fiscal 2001-2005 planning period. This plan is a product of nearly two years of field studies and research, public scoping, and coordination with the Rainwater Advisory Committee. The committee consists of representatives from tribal government, state agencies, local government, public organizations, and members of the public. The plan is organized into several sections with Chapter 1 providing introductory information such as project location, purpose and need, project goals and objectives, common elements and assumptions, coordination efforts and public scoping, and historical information about the project area. Key issues are presented in Chapter 2 and Chapter 3 discusses existing resource conditions within the wildlife area. Chapter 4 provides a detailed presentation on management activities and Chapter 5 outlines a monitoring and evaluation plan for the project that will help assess whether the project is meeting the intended purpose and need and the goals and objectives. Chapter 6 displays the action plan and provides a prioritized list of actions with associated budget for the next five year period. Successive chapters contain appendices, references, definitions, and a glossary. The purpose of the project is

  13. Freihoelser Forst Local Training Area Demonstration Project: Prescription development and installation

    SciTech Connect

    Hinchman, R.R.; Zellmer, S.D.; Severinghaus, W.D.; Brent, J.J.

    1989-04-01

    The Freiholser Forst Local Training Area (LTA) Rehabilitation Demonstration Project is part of the Integrated Training Area Management program being developed by the US Army Corps of Engineers` Construction Engineering Research Laboratory for the Seventh Army Training Command of the US Army in Europe. The rehabilitation demonstration project was begun in 1987 to develop and demonstrate rapid, cost-effective methods to stabilize the LTA`s barren, eroding maneuver areas and make training conditions more realistic. The sandy, infertile, and acidic soils at the LTA are considered the major factor limiting rehabilitation efforts there. The project involves the evaluation of three procedures to revegetate the soils, each incorporating identical methods for preparing the seedbed and a single seed mixture consisting of adapted, native species but using different soil amendments. All three treatments have satisfactorily reestablished vegetation and controlled erosion on the demonstration plots at the LTA, but their costs have varied widely.

  14. Freihoelser Forst Local Training Area Demonstration Project: Prescription development and installation

    SciTech Connect

    Hinchman, R.R.; Zellmer, S.D. . Energy Systems Div.); Severinghaus, W.D. ); Brent, J.J. )

    1989-04-01

    The Freiholser Forst Local Training Area (LTA) Rehabilitation Demonstration Project is part of the Integrated Training Area Management program being developed by the US Army Corps of Engineers' Construction Engineering Research Laboratory for the Seventh Army Training Command of the US Army in Europe. The rehabilitation demonstration project was begun in 1987 to develop and demonstrate rapid, cost-effective methods to stabilize the LTA's barren, eroding maneuver areas and make training conditions more realistic. The sandy, infertile, and acidic soils at the LTA are considered the major factor limiting rehabilitation efforts there. The project involves the evaluation of three procedures to revegetate the soils, each incorporating identical methods for preparing the seedbed and a single seed mixture consisting of adapted, native species but using different soil amendments. All three treatments have satisfactorily reestablished vegetation and controlled erosion on the demonstration plots at the LTA, but their costs have varied widely.

  15. Patterns and variability of projected bioclimatic habitat for Pinus albicaulis in the Greater Yellowstone Area.

    PubMed

    Chang, Tony; Hansen, Andrew J; Piekielek, Nathan

    2014-01-01

    Projected climate change at a regional level is expected to shift vegetation habitat distributions over the next century. For the sub-alpine species whitebark pine (Pinus albicaulis), warming temperatures may indirectly result in loss of suitable bioclimatic habitat, reducing its distribution within its historic range. This research focuses on understanding the patterns of spatiotemporal variability for future projected P.albicaulis suitable habitat in the Greater Yellowstone Area (GYA) through a bioclimatic envelope approach. Since intermodel variability from General Circulation Models (GCMs) lead to differing predictions regarding the magnitude and direction of modeled suitable habitat area, nine bias-corrected statistically down-scaled GCMs were utilized to understand the uncertainty associated with modeled projections. P.albicaulis was modeled using a Random Forests algorithm for the 1980-2010 climate period and showed strong presence/absence separations by summer maximum temperatures and springtime snowpack. Patterns of projected habitat change by the end of the century suggested a constant decrease in suitable climate area from the 2010 baseline for both Representative Concentration Pathways (RCPs) 8.5 and 4.5 climate forcing scenarios. Percent suitable climate area estimates ranged from 2-29% and 0.04-10% by 2099 for RCP 8.5 and 4.5 respectively. Habitat projections between GCMs displayed a decrease of variability over the 2010-2099 time period related to consistent warming above the 1910-2010 temperature normal after 2070 for all GCMs. A decreasing pattern of projected P.albicaulis suitable habitat area change was consistent across GCMs, despite strong differences in magnitude. Future ecological research in species distribution modeling should consider a full suite of GCM projections in the analysis to reduce extreme range contractions/expansions predictions. The results suggest that restoration strageties such as planting of seedlings and controlling

  16. Patterns and Variability of Projected Bioclimatic Habitat for Pinus albicaulis in the Greater Yellowstone Area

    PubMed Central

    Chang, Tony; Hansen, Andrew J.; Piekielek, Nathan

    2014-01-01

    Projected climate change at a regional level is expected to shift vegetation habitat distributions over the next century. For the sub-alpine species whitebark pine (Pinus albicaulis), warming temperatures may indirectly result in loss of suitable bioclimatic habitat, reducing its distribution within its historic range. This research focuses on understanding the patterns of spatiotemporal variability for future projected P.albicaulis suitable habitat in the Greater Yellowstone Area (GYA) through a bioclimatic envelope approach. Since intermodel variability from General Circulation Models (GCMs) lead to differing predictions regarding the magnitude and direction of modeled suitable habitat area, nine bias-corrected statistically down-scaled GCMs were utilized to understand the uncertainty associated with modeled projections. P.albicaulis was modeled using a Random Forests algorithm for the 1980–2010 climate period and showed strong presence/absence separations by summer maximum temperatures and springtime snowpack. Patterns of projected habitat change by the end of the century suggested a constant decrease in suitable climate area from the 2010 baseline for both Representative Concentration Pathways (RCPs) 8.5 and 4.5 climate forcing scenarios. Percent suitable climate area estimates ranged from 2–29% and 0.04–10% by 2099 for RCP 8.5 and 4.5 respectively. Habitat projections between GCMs displayed a decrease of variability over the 2010–2099 time period related to consistent warming above the 1910–2010 temperature normal after 2070 for all GCMs. A decreasing pattern of projected P.albicaulis suitable habitat area change was consistent across GCMs, despite strong differences in magnitude. Future ecological research in species distribution modeling should consider a full suite of GCM projections in the analysis to reduce extreme range contractions/expansions predictions. The results suggest that restoration strageties such as planting of seedlings and

  17. St. Louis Area Earthquake Hazards Mapping Project - December 2008-June 2009 Progress Report

    USGS Publications Warehouse

    Williams, R.A.; Bauer, R.A.; Boyd, O.S.; Chung, J.; Cramer, C.H.; Gaunt, D.A.; Hempen, G.L.; Hoffman, D.; McCallister, N.S.; Prewett, J.L.; Rogers, J.D.; Steckel, P.J.; Watkins, C.M.

    2009-01-01

    This report summarizes the mission, the project background, the participants, and the progress of the St. Louis Area Earthquake Hazards Mapping Project (SLAEHMP) for the period from December 2008 through June 2009. During this period, the SLAEHMP held five conference calls and two face-to-face meetings in St. Louis, participated in several earthquake awareness public meetings, held one outreach field trip for the business and government community, collected and compiled new borehole and digital elevation data from partners, and published a project summary.

  18. Area tracking in topographical in-vivo measurement series of human skin by displacement vector fields

    NASA Astrophysics Data System (ADS)

    Hopermann, Hermann; Lunderstaedt, Reinhart A.

    2000-12-01

    In the first part of the presented paper a new measurement system for fast three-dimensional in vivo measurement of the microtopography of human skin is proposed. It is based on the principle of active image triangulation. A Digital Micromirror Device (DMDTM) is used for projecting sinusoidal intensity distributions on the surface of human skin. By using temporal phase shift algorithms the three-dimensional topography is reconstructed from two-dimensional images. Displacement vector fields represent a promising approach for detecting deformation and other lateral changes in the surface of human skin. In the second part of the presented paper a method based on local template matching and smooth interpolation algorithms for determining a displacement vector field is proposed. Aiming at a minimal expenditure of numerical calculation, a stepwise algorithm was developed for this purpose. The deformatory component of the calculated vector field is separated by minimizing a suitable functional, which is also presented in the paper. In investigations of measurement series the proposed method proves to be very efficient. The calculated displacement vector fields connect corresponding areas in two subsequent measurements. Distortions caused by mechanical deformation or other influences can be detected and visualized by the separated deformatory components of the vector fields.

  19. EPA Critical Path Science Plan Projects 19, 20 and 21: Human and Bovine Source Detection

    EPA Science Inventory

    The U.S. EPA Critical Path Science Plan Projects are: Project 19: develop novel bovine and human host-specific PCR assays and complete performance evaluation with other published methods. Project 20: Evaluate human-specific assays with water samples impacted with different lev...

  20. Mapping multisensory parietal face and body areas in humans.

    PubMed

    Huang, Ruey-Song; Chen, Ching-fu; Tran, Alyssa T; Holstein, Katie L; Sereno, Martin I

    2012-10-30

    Detection and avoidance of impending obstacles is crucial to preventing head and body injuries in daily life. To safely avoid obstacles, locations of objects approaching the body surface are usually detected via the visual system and then used by the motor system to guide defensive movements. Mediating between visual input and motor output, the posterior parietal cortex plays an important role in integrating multisensory information in peripersonal space. We used functional MRI to map parietal areas that see and feel multisensory stimuli near or on the face and body. Tactile experiments using full-body air-puff stimulation suits revealed somatotopic areas of the face and multiple body parts forming a higher-level homunculus in the superior posterior parietal cortex. Visual experiments using wide-field looming stimuli revealed retinotopic maps that overlap with the parietal face and body areas in the postcentral sulcus at the most anterior border of the dorsal visual pathway. Starting at the parietal face area and moving medially and posteriorly into the lower-body areas, the median of visual polar-angle representations in these somatotopic areas gradually shifts from near the horizontal meridian into the lower visual field. These results suggest the parietal face and body areas fuse multisensory information in peripersonal space to guard an individual from head to toe. PMID:23071340

  1. Columbia Basin Wildlife Mitigation Project : Rainwater Wildlife Area Final Management Plan.

    SciTech Connect

    Childs, Allen

    2002-03-01

    This Draft Management Plan has been developed by the Confederated Tribes of the Umatilla Indian Reservation (CTUIR) to document how the Rainwater Wildlife Area (formerly known as the Rainwater Ranch) will be managed. The plan has been developed under a standardized planning process developed by the Bonneville Power Administration (BPA) for Columbia River Basin Wildlife Mitigation Projects (See Appendix A and Guiding Policies Section below). The plan outlines the framework for managing the project area, provides an assessment of existing conditions and key resource issues, and presents an array of habitat management and enhancement strategies. The plan culminates into a 5-Year Action Plan that will focus our management actions and prioritize funding during the Fiscal 2001-2005 planning period. This plan is a product of nearly two years of field studies and research, public scoping, and coordination with the Rainwater Advisory Committee. The committee consists of representatives from tribal government, state agencies, local government, public organizations, and members of the public. The plan is organized into several sections with Chapter 1 providing introductory information such as project location, purpose and need, project goals and objectives, common elements and assumptions, coordination efforts and public scoping, and historical information about the project area. Key issues are presented in Chapter 2 and Chapter 3 discusses existing resource conditions within the wildlife area. Chapter 4 provides a detailed presentation on management activities and Chapter 5 outlines a monitoring and evaluation plan for the project that will help assess whether the project is meeting the intended purpose and need and the goals and objectives. Chapter 6 displays the action plan and provides a prioritized list of actions with associated budget for the next five year period. Successive chapters contain appendices, references, definitions, and a glossary.

  2. Mapping human interaction with the Bering Sea ecosystem: Comparing seasonal use areas, lifetime use areas, and "calorie-sheds"

    NASA Astrophysics Data System (ADS)

    Huntington, Henry P.; Ortiz, Ivonne; Noongwook, George; Fidel, Maryann; Childers, Dorothy; Morse, Muriel; Beaty, Julia; Alessa, Lilian; Kliskey, Andrew

    2013-10-01

    Alaska Native coastal communities interact with the marine environment in many ways, especially through the harvest of fish, marine mammals, and seabirds. The spatial characteristics of this interaction are often depicted in terms of subsistence use areas: the places where harvests and associated travel occur. Another way to consider the interaction is to examine the areas where harvested species range during their lifecycle or annual migratory path. In this paper, we compare seasonal subsistence use areas, lifetime subsistence use areas, and "calorie-sheds," or the area over which harvested species range. Each perspective offers useful information concerning not only the nature of human-environment interactions but also the scope for potential conflict with other human activity and the means by which such conflicts could be reduced, avoided, or otherwise addressed. Seasonal subsistence use areas can be used to manage short-term activities, such as seasonal vessel traffic during community re-supply. Lifetime subsistence use areas indicate the area required to allow hunters and fishers the flexibility to adjust to interannual variability and perhaps to adapt to a changing environment. Calorie-sheds indicate the areas about which a community may be concerned due to potential impacts on the species they harvest.

  3. Nevada Test Site Area 25. Radiological survey and cleanup project, 1974-1983. Final report

    SciTech Connect

    McKnight, R.K.; Rosenberry, C.E.; Orcutt, J.A.

    1984-01-01

    This report describes radiological survey, decontamination and decommissioning of the Nevada Test Site (NTS) Area 25 facilities and land areas incorporated in the Nuclear Rocket Development Station (NRDS). Buildings, facilities and support systems used after 1959 for nuclear reactor and engine testing were surveyed for the presence of radioactive contamination. The cleanup was part of the Surplus Facilities Management Program funded by the Department of Energy's Richland Operations Office. The radiological survey portion of the project encompassed portable instrument surveys and removable contamination surveys (swipe) for alpha and beta plus gamma radiation contamination of facilities, equipment and land areas. Soil sampling was also accomplished. The majority of Area 25 facilities and land areas have been returned to unrestricted use. Remaining radiologically contaminated areas are posted with warning signs and barricades. 12 figures.

  4. 76 FR 16609 - Proposed Information Collection; Comment Request; Identification of Human Cell Lines Project

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-24

    ...; Identification of Human Cell Lines Project AGENCY: National Institute of Standards and Technology (NIST...) profiling up to 1500 human cell line samples as part of the Identification of Human Cell Lines Project. All... for Biotechnology Information (NCBI) and will be used to differentiate among cell lines, as...

  5. The Visible Human Project: a resource for anatomical visualization.

    PubMed

    Ackerman, M J

    1998-01-01

    The National Library of Medicine (NLM) has long been a world leader in the archiving and distribution of the print-based images of biology and medicine. NLM has also been a pioneer in the use of computer systems to encode and distribute textual knowledge of the life sciences. NLM's Long Range Planning effort of 1985-86 foresaw a coming era where NLM's Bibliographic and factual database services would be complemented by libraries of digital images, distributed over high speed computer networks and by high capacity physical media. The NLM Planning Panel on Electronic Imaging recommended that NLM should undertake the building a digital image library consisting of computerized tomography (CT) and magnetic resonance (MR) images, and cryosection images of a representative, carefully selected and prepared male and female cadaver--the "Visible Human ProjectJ." The male and female Visible Human data sets are now being made available through a license agreement with the NLM. The data sets are supporting a wide range of educational, diagnostic, treatment planning, and commercial uses. The value of this international resource in the public domain increases through its application. Its utility will continue to grow as related databases are attached to it, and as more attributes are given to its image elements. PMID:10384616

  6. The United States Department of Agriculture northeast area-wide tick control project - history and protocol

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This manuscript summarizes the history of development of the ARS-patented ‘4-Poster’ Deer Treatment Bait Station technology for the control of ticks feeding on white-tailed deer and other wild ungulates, provides the rationale for its use in the USDA Northeast Area-wide Tick Control Project, and des...

  7. D-Area Drip Irrigation/Phytoremediation Project: SRTC Report on Phase 1

    SciTech Connect

    Wilde, E.W.

    2001-09-11

    The overall objective of this project is to evaluate a novel drip irrigation-phytoremediation process for remediating volatile organic contaminants (VOCs), primarily trichloroethylene (TCE), from groundwater in D-Area at the Savannah River Site (SRS). The process is expected to be less expensive and more beneficial to the environment than alternative TCE remediation technologies.

  8. Evaluation of the USDA Northeast Area-wide Tick Control Project by Meta-analysis

    Technology Transfer Automated Retrieval System (TEKTRAN)

    As part of the Northeast Area-wide Tick Control Project (NEATCP), meta-analyses were performed using pooled data on the extent of tick-vector control achieved through seven concurrent studies, conducted within five states, using USDA ‘4-Poster’ devices to deliver targeted-acaricide to white-tailed d...

  9. Wisconsin Area Planning and Development. Consortium Project, Title I, Higher Education Act 1965.

    ERIC Educational Resources Information Center

    Wisconsin Univ., Madison. Univ. Extension.

    The Consortium for Area Planning and Development was established in 1967 to implement the basic purposes of Title I of the Higher Education Act of 1965. The Consortium's first seminar was held in May 1968 and was attended by 25 project leaders, local and state government officials, technical consultants, and representatives of various institutions…

  10. P.C.A.P. Project Profiles. Queensland Priority Country Area Program--Evaluation Series.

    ERIC Educational Resources Information Center

    Fowler, C. F.; Peters, J. E.

    Thirty-two projects designed to improve educational opportunities of rural Queensland children were funded as part of the Disadvantaged Schools Program in 1979 and 1980. This program resulted from a 1977-79 Schools Commission report which suggested that students in country areas may be disadvantaged compared to urban dwellers, with respect to…