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Sample records for idp signature processing

  1. History of Nebular Processing Traced by Silicate Stardust in IDPS

    NASA Technical Reports Server (NTRS)

    Messenger, Scott R.; Keller, L. P.; Nakamura-Messenger, K.

    2010-01-01

    Chondritic porous interplanetary dust particles (CP-IDPs) may be the best preserved remnants of primordial solar system materials, in part because they were not affected by parent body hydrothermal alteration. Their primitive characteristics include fine grained, unequilibrated, anhydrous mineralogy, enrichment in volatile elements, and abundant molecular cloud material and silicate stardust. However, while the majority of CP-IDP materials likely derived from the Solar System, their formation processes and provenance are poorly constrained. Stardust abundances provide a relative measure of the extent of processing that the Solar System starting materials has undergone in primitive materials. For example, among primitive meteorites silicate stardust abundances vary by over two orders of magnitude (less than 10-200 ppm). This range of abundances is ascribed to varying extents of aqueous processing in the meteorite parent bodies. The higher average silicate stardust abundances among CP-IDPs (greater than 375 ppm) are thus attributable to the lack of aqueous processing of these materials. Yet, silicate stardust abundances in IDPs also vary considerably. While the silicate stardust abundance in IDPs having anomalous N isotopic compositions was reported to be 375 ppm, the abundance in IDPs lacking N anomalies is less than 10 ppm. Furthermore, these values are significantly eclipsed among some IDPs with abundances ranging from 2,000 ppm to 10,000 ppm. Given that CP-IDPs have not been significantly affected by parent body processes, the difference in silicate stardust abundances among these IDPs must reflect varying extents of nebular processing. Here we present recent results of a systematic coordinated mineralogical/isotopic study of large cluster IDPs aimed at (1) characterizing the mineralogy of presolar silicates and (2) delineating the mineralogical and petrographic characteristics of IDPs with differing silicate stardust abundances. One of the goals of this study is

  2. IDP: Image and data processing (software) in C++

    SciTech Connect

    Lehman, S.

    1994-11-15

    IDP++(Image and Data Processing in C++) is a complied, multidimensional, multi-data type, signal processing environment written in C++. It is being developed within the Radar Ocean Imaging group and is intended as a partial replacement for View. IDP++ takes advantage of the latest object-oriented compiler technology to provide `information hiding.` Users need only know C, not C++. Signals are treated like any other variable with a defined set of operators and functions in an intuitive manner. IDP++ is being designed for real-time environment where interpreted signal processing packages are less efficient.

  3. History of Nebular Processing Traced by Silicate Stardust in IDPs

    NASA Astrophysics Data System (ADS)

    Messenger, S.; Keller, L. P.; Nakamura-Messenger, K.; Nguyen, A.

    2010-03-01

    We have identified two presolar silicate grains as polycrystalline assemblages, or equilibrated aggregates. These grains occur in a stardust-rich interplanetary dust particle (IDP). We propose these grains were annealed in the solar nebula.

  4. IDP++: signal and image processing algorithms in C++ version 4.1

    SciTech Connect

    Lehman, S.K.

    1996-11-01

    IDP++ (Image and Data Processing in C++) is a collection of signal and image processing algorithms written in C++. It is a compiled signal processing environment which supports four data types of up to four dimensions. It is developed within Lawrence Livermore National Laboratory`s Image and Data Processing group as a partial replacement for View. IDP ++ takes advantage of the latest, implemented and actually working, object-oriented compiler technology to provide `information hiding.` Users need only know C, not C++. Signals are treated like any other variable with a defined set of operators and functions in an intuitive manner. IDP++ is designed for real-time environment where interpreted processing packages are less efficient. IDP++ exists for both SUNs and Silicon Graphics using their most current compilers.

  5. NPOESS IDPS

    NASA Astrophysics Data System (ADS)

    Mulligan, J.; Ripley, M.

    2009-12-01

    NPOESS, the National Polar-orbiting Operational Environmental Satellite System, represents the U.S., next generation, polar-orbiting, Low-Earth-Orbit [LEO] satellite constellation and end-to-end system for environmental remote sensing. The NPOESS program is comprised of the spacecraft, instruments and sensors on the spacecraft, the command, control and communications infrastructure, data processing software and hardware, and launch support capabilities. The NPOESS program also includes the NPOESS Preparatory Project (NPP), a risk reduction mission managed jointly by the NPOESS Integrated Program Office (IPO) and NASA. It provides an opportunity for NPOESS to demonstrate and validate new sensors, algorithms, and operational processing capabilities, and to test many components of the system prior to the first NPOESS flight. NPP also provides continuity between the current Earth Observing System (EOS) and NPOESS for select remotely sensed data that support global climate studies and research. The NPOESS Ground System will provide data to the DoD and DOC weather Centrals (the Air Force Weather Agency (AFWA), the Fleet Numerical Meteorology and Oceanography Center (FNMOC), the Naval Oceanographic Office (NAVOCEANO) and the National Environmental Satellite, Data, and Information Service (NESDIS)) in unprecedented latency. All Interface Data Processing Segment (IDPS) installations consist of the hardware and software necessary to receive and process raw satellite data into Environmental Data Records (EDRs). An architecture with an IDP at each of the four Centrals, each capable of generating all the products, was derived after studying the communications cost to transmit the products from a centralized location. Additionally, the data products will be provided to NOAA’s Comprehensive Large-Array data Stewardship System (CLASS) for distribution to the broader scientific user community.

  6. TEM and NanoSIMS Study of Hydrated/Anhydrous Phase Mixed IDPs: Cometary or Asteroidal Origin?

    NASA Technical Reports Server (NTRS)

    Nakamura, K.; Messenger, S.; Keller, L. P.

    2005-01-01

    Chondritic interplanetary dust particles (IDPs) are subdivided into (1) particles that form highly porous aggregates (chondritic porous "CP" IDPs), and (2) smooth particles ("CS" IDPs). Infrared (IR) spectroscopy has been a valuable tool for non-destructively determining the bulk mineralogy of IDPs. Most IDPs fall within three distinct IR groups: (1) olivine-rich particles, (2) pyroxene-rich particles, and (3) phyllosilicate-rich particles. From the IR studies, IDPs dominated by anhydrous minerals tend to be fine grained (CP), while phyllosilicate-rich IDPs are mostly CS. CP IDPs have been linked to cometary sources based on their compositions, spectral properties, and atmospheric entry velocities. Since no spectral signatures of hydrated minerals have been detected in comets, CS IDPs are thought to derive from primitive asteroids. Transmission electron microscopy (TEM) studies have revealed that the mineralogical distinctions between CP and CS IDPs are not always clear. Previous investigators have reported trace amounts of hydrous minerals in dominantly anhydrous particles. A better understanding of these particles will help to elucidate whether there is a genetic relationship between anhydrous and hydrated IDPs, provide insight into the earliest stages of aqueous alteration of primitive materials, and may help to determine whether comets have experienced any aqueous processing. Here we report a combined TEM and isotopic imaging study of an unusual anhydrous IDP with hydrated phases. Additional information is included in the original extended abstract.

  7. Nonlinear image filtering within IDP++

    SciTech Connect

    Lehman, S.K.; Wieting, M.G.; Brase, J.M.

    1995-02-09

    IDP++, image and data processing in C++, is a set of a signal processing libraries written in C++. It is a multi-dimension (up to four dimensions), multi-data type (implemented through templates) signal processing extension to C++. IDP++ takes advantage of the object-oriented compiler technology to provide ``information hiding.`` Users need only know C, not C++. Signals or data sets are treated like any other variable with a defined set of operators and functions. We here some examples of the nonlinear filter library within IDP++. Specifically, the results of MIN, MAX median, {alpha}-trimmed mean, and edge-trimmed mean filters as applied to a real aperture radar (RR) and synthetic aperture radar (SAR) data set.

  8. IDPs at Work

    ERIC Educational Resources Information Center

    Hirsh, Åsa

    2015-01-01

    The present study concerns Swedish teachers' practices with regard to individual development plans (IDPs), which are mandatory for all students in compulsory school. The conceptual points of departure are taken from Wartofsky's distinctions between primary, secondary, and tertiary artifacts and the concepts of inscription and…

  9. Developments in Signature Process Control

    NASA Astrophysics Data System (ADS)

    Keller, L. B.; Dominski, Marty

    1993-01-01

    Developments in the adaptive process control technique known as Signature Process Control for Advanced Composites (SPCC) are described. This computer control method for autoclave processing of composites was used to develop an optimum cure cycle for AFR 700B polyamide and for an experimental poly-isoimide. An improved process cycle was developed for Avimid N polyamide. The potential for extending the SPCC technique to pre-preg quality control, press modeling, pultrusion and RTM is briefly discussed.

  10. The Abundance and Distribution of Presolar Materials in Cluster IDPS

    NASA Technical Reports Server (NTRS)

    Messenger, Scott; Keller, Lindsay; Nakamura-Messenger, Keiko; Ito, Motoo

    2007-01-01

    Presolar grains and remnants of interstellar organic compounds occur in a wide range of primitive solar system materials, including meteorites, interplanetary dust particles (IDPs), and comet Wild-2 samples. Among the most abundant presolar phases are silicate stardust grains and molecular cloud material. However, these materials have also been susceptible to destruction and alteration during parent body and nebular processing. In addition to their importance as direct samples of remote and ancient astrophysical environments, presolar materials thus provide a measure of how well different primitive bodies have preserved the original solar system starting materials. The matrix normalized abundances of presolar silicate grains in meteorites range from 20 ppm in Semarkona and Bishunpur to 170 ppm for Acfer 094. The lower abundances of presolar silicates in Bishunpur and Semarkona has been ascribed to the destruction of presolar silicates during aqueous processes. Presolar silicates appear to be significantly more abundant in anhydrous IDPs, possibly because these materials did not experience parent body hydrothermal alteration. Among IDPs the estimated abundances of presolar silicates vary by more than an order of magnitude, from 480 to 5500 ppm. The wide disparity in the abundances of presolar silicates of IDPs may be a consequence of the relatively small total area analyzed in those studies and the fine grain sizes of the IDPs. Alternatively, there may be a wide range in presolar silicate abundances between different IDPs. This view is supported by the observation that 15N-rich IDPs have higher presolar silicate abundances than those with isotopically normal N.

  11. Signatures of mutational processes in human cancer

    PubMed Central

    Alexandrov, Ludmil B.; Nik-Zainal, Serena; Wedge, David C.; Aparicio, Samuel A.J.R.; Behjati, Sam; Biankin, Andrew V.; Bignell, Graham R.; Bolli, Niccolo; Borg, Ake; Børresen-Dale, Anne-Lise; Boyault, Sandrine; Burkhardt, Birgit; Butler, Adam P.; Caldas, Carlos; Davies, Helen R.; Desmedt, Christine; Eils, Roland; Eyfjörd, Jórunn Erla; Foekens, John A.; Greaves, Mel; Hosoda, Fumie; Hutter, Barbara; Ilicic, Tomislav; Imbeaud, Sandrine; Imielinsk, Marcin; Jäger, Natalie; Jones, David T.W.; Jones, David; Knappskog, Stian; Kool, Marcel; Lakhani, Sunil R.; López-Otín, Carlos; Martin, Sancha; Munshi, Nikhil C.; Nakamura, Hiromi; Northcott, Paul A.; Pajic, Marina; Papaemmanuil, Elli; Paradiso, Angelo; Pearson, John V.; Puente, Xose S.; Raine, Keiran; Ramakrishna, Manasa; Richardson, Andrea L.; Richter, Julia; Rosenstiel, Philip; Schlesner, Matthias; Schumacher, Ton N.; Span, Paul N.; Teague, Jon W.; Totoki, Yasushi; Tutt, Andrew N.J.; Valdés-Mas, Rafael; van Buuren, Marit M.; van ’t Veer, Laura; Vincent-Salomon, Anne; Waddell, Nicola; Yates, Lucy R.; Zucman-Rossi, Jessica; Futreal, P. Andrew; McDermott, Ultan; Lichter, Peter; Meyerson, Matthew; Grimmond, Sean M.; Siebert, Reiner; Campo, Elías; Shibata, Tatsuhiro; Pfister, Stefan M.; Campbell, Peter J.; Stratton, Michael R.

    2013-01-01

    All cancers are caused by somatic mutations. However, understanding of the biological processes generating these mutations is limited. The catalogue of somatic mutations from a cancer genome bears the signatures of the mutational processes that have been operative. Here, we analysed 4,938,362 mutations from 7,042 cancers and extracted more than 20 distinct mutational signatures. Some are present in many cancer types, notably a signature attributed to the APOBEC family of cytidine deaminases, whereas others are confined to a single class. Certain signatures are associated with age of the patient at cancer diagnosis, known mutagenic exposures or defects in DNA maintenance, but many are of cryptic origin. In addition to these genome-wide mutational signatures, hypermutation localized to small genomic regions, kataegis, is found in many cancer types. The results reveal the diversity of mutational processes underlying the development of cancer with potential implications for understanding of cancer etiology, prevention and therapy. PMID:23945592

  12. Nitrogen Isotopic Composition of Organic Matter in a Pristine Collection IDP

    NASA Technical Reports Server (NTRS)

    Messenger, S.; Nakamura-Messenger, K.; Keller, L. P.; Clemett, S. J.; Nguyen, A. N.; Walker, Robert M.

    2012-01-01

    Anhydrous chondritic porous interplanetary dust particles (CP IDPs) are probable cometary materials that show primitive characteristics, such as unequilibrated mineralogy, fragile structure, and abundant presolar grains and organic matter [1-3]. CP IDPs are richer in aliphatic species and N-bearing aromatic hydrocarbons than meteoritic organics and commonly exhibit highly anomalous H and N isotopic compositions [4,5]. Cometary organic matter is of interest in part because it has escaped the hydrothermal processing experienced by meteorites. However, IDPs are collected using silicon oil that must be removed with strong organic solvents such as hexane. This procedure is likely to have removed some fraction of soluble organic phases in IDPs. We recently reported the first stratospheric collection of IDPs without the use of silicone oil [6]. Here we present initial studies of the carbonaceous material in an IDP from this collection.

  13. Elemental Composition of Primitive Anhydrous IDPs

    NASA Astrophysics Data System (ADS)

    Flynn, G.; Wirick, S.; Sutton, S. R.; Lanzirotti, A.

    2015-10-01

    We measured elemental compositions of five large anhydrous cluster interplanetary dust particles (IDPs) that show no evidence of significant thermal alteration during atmospheric entry and found their mean composition to be very similar to that of primitive CI meteorites. Our results indicate that the enrichment in moderately volatile elements and the depletion in S found in the ~10 μm anhydrous, chondritic porous (CP) IDPs, the matrix of these cluster IDPs, are not representative of the composition of their parent body. The inclusion of larger (>10 μm) volatile-poor silicates as well as sulfides in the large anhydrous cluster IDPs, which sample the CP IDP parent body at a larger size scale, suggests the large cluster IDPs are unbiased samples of the condensable material of the Solar Nebula.

  14. Chemical compositions of large cluster IDPs

    SciTech Connect

    Flynn, G.J.; Lanzirotti, A.; Sutton, S.R.

    2006-12-06

    We performed X-ray fluorescence spectroscopy on two large cluster IDPs, which sample the IDP parent body at a mass scale two orders-of-magnitude larger than {approx}10 {micro}m IDPs, allowing proper incorporation of larger mineral grains into the bulk composition of the parent body. We previously determined that {approx}10 {micro}m interplanetary dust particles (IDPs) collected from the Earth's stratosphere are enriched in many moderately volatile elements by a factor of {approx}3 over the CI meteorites. However, these IDP measurements provide no direct constraint on the bulk chemical composition of the parent body (or parent bodies) of the IDPs. Collisions are believed to be the major mechanism for dust production by the asteroids, producing dust by surface erosion, cratering and catastrophic disruption. Hypervelocity impact experiments at {approx}5 km/sec, which is the mean collision velocity in the main belt, performed by Flynn and Durda on ordinary chondrite meteorites and the carbonaceous chondrite meteorite Allende show that the 10 {micro}m debris is dominated by matrix material while the debris larger than {approx}25 {micro}m is dominated by chondrule fragments. Thus, if the IDP parent body is similar in structure to the chondritic meteorites, it is likely that the {approx}10 {micro}m IDPs oversample the fine-grained component of the parent body. We have examined the matrix material from the few meteorites that are sufficiently fine-grained to be samples of potential IDP parent bodies. This search has, thus far, not produced a compositional and mineralogical match to either the hydrous or anhydrous IDPs. This result, coupled with our recent mapping of the element distributions, which indicates the enrichment of moderately volatile elements is not due to contamination on their surfaces, suggests the IDPs represent a new type of extraterrestrial material. Nonetheless, the meteorite fragmentation results suggest that compositional measurements on 10 {micro

  15. Multivalent IDP assemblies: Unique properties of LC8-associated, IDP duplex scaffolds.

    PubMed

    Clark, Sarah A; Jespersen, Nathan; Woodward, Clare; Barbar, Elisar

    2015-09-14

    A wide variety of subcellular complexes are composed of one or more intrinsically disordered proteins (IDPs) that are multivalent, flexible, and characterized by dynamic binding of diverse partner proteins. These multivalent IDP assemblies, of broad functional diversity, are classified here into five categories distinguished by the number of IDP chains and the arrangement of partner proteins in the functional complex. Examples of each category are summarized in the context of the exceptional molecular and biological properties of IDPs. One type - IDP duplex scaffolds - is considered in detail. Its unique features include parallel alignment of two IDP chains, formation of new self-associated domains, enhanced affinity for additional bivalent ligands, and ubiquitous binding of the hub protein LC8. For two IDP duplex scaffolds, dynein intermediate chain IC and nucleoporin Nup159, these duplex features, together with the inherent flexibility of IDPs, are central to their assembly and function. A new type of IDP-LC8 interaction, distributed binding of LC8 among multiple IDP recognition sites, is described for Nup159 assembly. PMID:26226419

  16. Extracellular Signatures as Indicators of Processing Methods

    SciTech Connect

    Wahl, Karen L.

    2012-01-09

    As described in other chapters within this volume, many aspects of microbial cells vary with culture conditions and therefore can potentially be analyzed as forensic signatures of growth conditions. In addition to changes or variations in components of the microbes themselves, extracellular materials indicative of production processes may remain associated with the final bacterial product. It is well recognized that even with considerable effort to make pure products such as fine chemicals or pharmaceuticals, trace impurities from components or synthesis steps associated with production processes can be detected in the final product. These impurities can be used as indicators of production source or methods, such as to help connect drugs of abuse to supply chains. Extracellular residue associated with microbial cells could similarly help to characterize production processes. For successful growth of microorganisms on culture media there must be an available source of carbon, nitrogen, inorganic phosphate and sulfur, trace metals, water and vitamins. The pH, temperature, and a supply of oxygen or other gases must also be appropriate for a given organism for successful culture. The sources of these components and the range in temperature, pH and other variables has adapted over the years with currently a wide range of possible combinations of media components, recipes and parameters to choose from for a given organism. Because of this wide variability in components, mixtures of components, and other parameters, there is the potential for differentiation of cultured organisms based on changes in culture conditions. The challenge remains how to narrow the field of potential combinations and be able to attribute variations in the final bacterial product and extracellular signatures associated with the final product to information about the culture conditions or recipe used in the production of that product.

  17. Signatures of nucleosynthesis in explosive stellar processes.

    NASA Astrophysics Data System (ADS)

    Wiescher, M.

    This paper presents a discussion of the characteristic observables of stellar explosions and compares the observed signatures such as light curve and abundance distribution with the respective values predicted in nucleosynthesis model calculations. Both the predicted energy generation as well as the abundance distribution in the ejecta depends critically on the precise knowledge of the reaction rates and decay processes involved in the nucleosynthesis reaction sequences. The important reactions and their influence on the production of the observed abundances will be discussed. The nucleosynthesis scenarios presented here are all based on explosive events at high temperature and density conditions. Many of the nuclear reactions involve unstable isotopes and are not well understood yet. To reduce the experimental uncertainties several radioactive beam experiments will be dicussed which will help to come to a better understanding of the correlated nucleosynthesis.

  18. High-Nickel Iron-Sulfides in Anhydrous, Gems-Rich CP IDPs

    NASA Technical Reports Server (NTRS)

    FLynn, G. J.; Keller, L. P.; Wirick, S.; Hu, W.; Li, L.; Yan, H.; Huang, X.; Nazaretski, E.; Lauer, K.; Chu, Y. S.

    2016-01-01

    Chondritic porous interplanetary dust particles (CP IDPs) that were not severly heated during atmospheric deceleration are the best preserved samples of the solids that condensed from the Solar protoplanetary disk, as well as pre-Solar grains thatr survived incorporation into the disk, currently available for laboratory analysis [1]. These CP IDPs never experienced the aqueous and/or thermal processing, gravitational compaction, and shock effects that overprinted the record of Solar nebula processes in meteorites.

  19. The topographic signature of anthropogenic geomorphic processes

    NASA Astrophysics Data System (ADS)

    Tarolli, P.; Sofia, G.

    2014-12-01

    Within an abiotic-dominated context, geomorphologic patterns and dynamics are single expressions of trade-offs between the physical resistance forces, and the mechanical and chemical forces related to climate and erosion. Recently, however, it has become essential for the geomorphological community to take into account also biota as a fundamental geomorphologic agent acting from local to regional scales. However, while there is a recent flourishing literature about the impacts of vegetation on geomorphic processes, the study of anthropogenic pressure on geomorphology is still at its early stages. Humans are indeed among the most prominent geomorphic agents, redistributing land surface, and causing drastic changes to the geomorphic organization of the landscape (e.g. intensive agriculture, urbanization), with direct consequences on land degradation and watershed response. The reconstruction or identification of artificial or anthropogenic topographies, therefore, provides a mechanism for quantifying anthropogenic changes to the landscape systems in the context of the Anthropocene epoch. High-resolution topographic data derived from the recent remote sensing technologies (e.g. lidar, SAR, SfM), offer now new opportunities to recognize better understand geomorphic processes from topographic signatures, especially in engineered landscapes where the direct anthropic alteration of processes is significant. It is possible indeed to better recognize human-induced geomorphic and anthropogenic features (e.g. road networks, agricultural terraces), and the connected erosion. The study presented here may allow improved understanding and targeted mitigation of the processes driving geomorphic changes during urban development and help guide future research directions for development-based watershed studies. Human society is deeply affecting the environment with consequences on the landscape. It is therefore fundamental to establish greater management control over the Earth

  20. Automated defect spatial signature analysis for semiconductor manufacturing process

    DOEpatents

    Tobin, Jr., Kenneth W.; Gleason, Shaun S.; Karnowski, Thomas P.; Sari-Sarraf, Hamed

    1999-01-01

    An apparatus and method for performing automated defect spatial signature alysis on a data set representing defect coordinates and wafer processing information includes categorizing data from the data set into a plurality of high level categories, classifying the categorized data contained in each high level category into user-labeled signature events, and correlating the categorized, classified signature events to a present or incipient anomalous process condition.

  1. The Abundance and Distribution of Presolar Materials in Cluster IDPS

    NASA Technical Reports Server (NTRS)

    Messenger, Scott; Keller, Lindsay; Nakamura-Messenger, Keiko; Ito, Motoo

    2007-01-01

    Presolar grains and remnants of interstellar organic compounds occur in a wide range of primitive solar system materials, including meteorites, interplanetary dust particles (IDPs), and comet Wild-2 samples. Among the most abundant presolar phases are silicate stardust grains and molecular cloud material. However, these materials have also been susceptible to destruction and alteration during parent body and nebular processing. In addition to their importance as direct samples of remote and ancient astrophysical environments, presolar materials thus provide a measure of how well different primitive bodies have preserved the original solar system starting materials.

  2. Oxygen isotopic signature of CO2 from combustion processes

    NASA Astrophysics Data System (ADS)

    Schumacher, M.; Neubert, R. E. M.; Meijer, H. A. J.; Jansen, H. G.; Brand, W. A.; Geilmann, H.; Werner, R. A.

    2008-11-01

    For a comprehensive understanding of the global carbon cycle precise knowledge of all processes is necessary. Stable isotope (13C and 18O) abundances provide information for the qualification and the quantification of the diverse source and sink processes. This study focuses on the δ18O signature of CO2 from combustion processes, which are widely present both naturally (wild fires), and human induced (fossil fuel combustion, biomass burning) in the carbon cycle. All these combustion processes use atmospheric oxygen, of which the isotopic signature is assumed to be constant with time throughout the whole atmosphere. The combustion is generally presumed to take place at high temperatures, thus minimizing isotopic fractionation. Therefore it is generally supposed that the 18O signature of the produced CO2 is equal to that of the atmospheric oxygen. This study, however, reveals that the situation is much more complicated and that important fractionation effects do occur. From laboratory studies fractionation effects in the order of about 26‰ became obvious, a clear differentiation of about 7‰ was also found in car exhausts which were sampled directly under ambient atmospheric conditions. We investigated a wide range of materials (both different raw materials and similar materials with different inherent 18O signature), sample geometries (e.g. texture and surface-volume ratios) and combustion circumstances. We found that the main factor influencing the specific isotopic signatures of the combustion-derived CO2 and of the concomitantly released oxygen-containing side products, is the case-specific rate of combustion. This points firmly into the direction of (diffusive) transport of oxygen to the reaction zone as the cause of the isotope fractionation. The original 18O signature of the material appeared to have little or no influence.

  3. Oxygen isotopic signature of CO2 from combustion processes

    NASA Astrophysics Data System (ADS)

    Schumacher, M.; Werner, R. A.; Meijer, H. A. J.; Jansen, H. G.; Brand, W. A.; Geilmann, H.; Neubert, R. E. M.

    2011-02-01

    For a comprehensive understanding of the global carbon cycle precise knowledge of all processes is necessary. Stable isotope (13C and 18O) abundances provide information for the qualification and the quantification of the diverse source and sink processes. This study focuses on the δ18O signature of CO2 from combustion processes, which are widely present both naturally (wild fires), and human induced (fossil fuel combustion, biomass burning) in the carbon cycle. All these combustion processes use atmospheric oxygen, of which the isotopic signature is assumed to be constant with time throughout the whole atmosphere. The combustion is generally presumed to take place at high temperatures, thus minimizing isotopic fractionation. Therefore it is generally supposed that the 18O signature of the produced CO2 is equal to that of the atmospheric oxygen. This study, however, reveals that the situation is much more complicated and that important fractionation effects do occur. From laboratory studies fractionation effects on the order of up to 26%permil; became obvious in the derived CO2 from combustion of different kinds of material, a clear differentiation of about 7‰ was also found in car exhausts which were sampled directly under ambient atmospheric conditions. We investigated a wide range of materials (both different raw materials and similar materials with different inherent 18O signature), sample geometries (e.g. texture and surface-volume ratios) and combustion circumstances. We found that the main factor influencing the specific isotopic signatures of the combustion-derived CO2 and of the concomitantly released oxygen-containing side products, is the case-specific rate of combustion. This points firmly into the direction of (diffusive) transport of oxygen to the reaction zone as the cause of the isotope fractionation. The original total 18O signature of the material appeared to have little influence, however, a contribution of specific bio-chemical compounds to

  4. Uncertainty in hydrological signatures for characterising rainfall-runoff processes

    NASA Astrophysics Data System (ADS)

    Westerberg, Ida; McMillan, Hilary

    2014-05-01

    Information about the characteristics of the runoff processes in a catchment is essential for most hydrological analyses, modelling and water-management applications. Such information derived from observed data is known as a hydrological or diagnostic signature, and have been used in a variety of studies for e.g. catchment classification, model-structural identification, model calibration and regionalisation - and in particular when using large hydrological datasets. Different sources of uncertainty in the observed data - including measurement error and representativeness as well as errors relating to data processing and management - propagate to the values of the derived signatures and reduce their information content. Subjective choices in the method used to calculate the signatures create a further source of uncertainty. The aim of this study was to contribute to the community's awareness and knowledge of observational uncertainty in hydrological signatures, including typical sources, magnitude and methods for its assessment. We first reviewed the sources and nature of uncertainties relevant to the calculation of different signatures based on rainfall and flow data. We then proposed a generally applicable method to calculate these uncertainties based on Monte Carlo sampling and demonstrated it for a number of commonly used signatures including thresholds in rainfall-runoff response, recession analysis and basic descriptive signatures such as total runoff ratio, and high/low flow statistics. The study was made for two data rich catchments, the 135 km2 Brue catchment in the UK and the 50 km2 Mahurangi catchment in New Zealand that are both densely monitored. For rainfall data the uncertainty sources included point measurement uncertainty, the number of gauges used in calculation of the catchment areal average, and epistemic uncertainties relating to lack of quality control. For flow data the uncertainty sources included uncertainties in stage/discharge measurement

  5. Human topographic signatures and derived geomorphic processes across landscapes

    NASA Astrophysics Data System (ADS)

    Tarolli, Paolo; Sofia, Giulia

    2016-02-01

    The Earth's surface morphology, in an abiotic context, is a consequence of major forcings such as tectonic uplift, erosion, sediment transport, and climate. Recently, however, it has become essential for the geomorphological community to also take into account biota as a geomorphological agent that has a role in shaping the landscape, even if at a different scale and magnitude from that of geology. Although the modern literature is flourishing on the impacts of vegetation on geomorphic processes, the study of anthropogenic pressures on geomorphology is still in its early stages. Topography emerges as a result of natural driving forces, but some human activities (such as mining, agricultural practices and the construction of road networks) directly or indirectly move large quantities of soil, which leave clear topographic signatures embedded on the Earth's morphology. These signatures can cause drastic changes to the geomorphological organization of the landscape, with direct consequences on Earth surface processes. This review provides an overview of the recent literature on the role of humans as a geological agent in shaping the morphology of the landscape. We explore different contexts that are significantly characterized by anthropogenic topographic signatures: landscapes affected by mining activities, road networks and agricultural practices. We underline the main characteristics of those landscapes and the implications of human impacts on Earth surface processes. The final section considers future challenges wherein we explore recent novelties and trials in the concept of anthropogenic geomorphology. Herein, we focus on the role of high-resolution topographic and remote-sensing technologies. The reconstruction or identification of artificial or anthropogenic topographies provides a mechanism for quantifying anthropogenic changes to landscape systems. This study may allow an improved understanding and targeted mitigation of the processes driving geomorphic

  6. Fairness influences early signatures of reward-related neural processing.

    PubMed

    Massi, Bart; Luhmann, Christian C

    2015-12-01

    Many humans exhibit a strong preference for fairness during decision-making. Although there is evidence that social factors influence reward-related and affective neural processing, it is unclear if this effect is mediated by compulsory outcome evaluation processes or results from slower deliberate cognition. Here we show that the feedback-related negativity (FRN) and late positive potential (LPP), two signatures of early hedonic processing, are modulated by the fairness of rewards during a passive rating task. We find that unfair payouts elicit larger FRNs than fair payouts, whereas fair payouts elicit larger LPPs than unfair payouts. This is true both in the time-domain, where the FRN and LPP are related, and in the time-frequency domain, where the two signals are largely independent. Ultimately, this work demonstrates that fairness affects the early stages of reward and affective processing, suggesting a common biological mechanism for social and personal reward evaluation. PMID:25962511

  7. Group Interpersonal Psychotherapy for depressed youth in IDP camps in Northern Uganda: adaptation and training.

    PubMed

    Verdeli, Helen; Clougherty, Kathleen; Onyango, Grace; Lewandowski, Eric; Speelman, Liesbeth; Betancourt, Teresa S; Neugebauer, Richard; Stein, Traci R; Bolton, Paul

    2008-07-01

    This article reviews the use of Interpersonal Psychotherapy (IPT) with depressed youth living in Internally Displaced Persons (IDP) camps in North Uganda. This youth has been exposed to severe losses and disruptions in relationships with caregivers, family, and community members; limited access to formal education; exposure to malnutrition and infections; and pressure to prematurely assume adult family roles. The process of adaptation to the content and training of IPT for these youth is presented and illustrated with case examples. PMID:18558315

  8. Coordinated Chemical and Isotopic Studies of GEMS in IDPS

    NASA Technical Reports Server (NTRS)

    Keller, L. P.; Messenger, S.

    2008-01-01

    Cometary IDPs contain a record of the building blocks of the solar system including presolar grains, molecular cloud material, and materials formed in the early solar nebula [1]. Following their accretion, these materials have remained relatively unaltered because of the lack of parent body hydrothermal alteration. We are using coordinated transmission electron microscope (TEM) and ion microprobe studies to establish the origins of the various components within cometary IDPs. Of particular interest is the nature and abundance of presolar silicates in these IDPs because astronomical observations suggest that crystalline and amorphous silicates are the dominant grain types produced in young main sequence stars and evolved O-rich stars [e.g. 2]. Amorphous silicates (in the form of GEMS grains) are a major component of cometary IDPs and so a major objective of this work is to elucidate their origins. In rare cases, GEMS grains have highly anomalous O isotopic compositions that establish their origins as circumstellar condensates [3]. Here we present data on a systematic study of the silicate components within a primitive IDP.

  9. Association of Presolar Grains with Molecular Cloud Material in IDPs

    NASA Technical Reports Server (NTRS)

    Messenger, S.; Keller, L. P.

    2005-01-01

    Anhydrous interplanetary dust particles (IDPs) collected in the stratosphere appear chemically, mineralogically, and texturally primitive in comparison to meteorites. Particles that escape significant atmospheric entry heating have highly unequilibrated mineralogy, are volatile element rich, and, overall, appear to have escaped significant parent body hydrothermal alteration. These IDPs are comprised of the building blocks of the solar system. The strongest evidence that anhydrous IDPs are primitive is that they contain abundant stardust and molecular cloud material. In particular, presolar silicates were first identified in IDPs and are present in abundances (450-5,500 ppm) that are well above that observed in primitive meteorites (less than 170 ppm). The most fragile (cluster) IDPs also commonly exhibit large H and N isotopic anomalies that likely originated by isotopic fractionation during extremely low temperature chemical reactions in a presolar cold molecular cloud. The D/H ratios exceed that of most primitive meteorites, and in rare cases reach values directly observed from simple gas phase molecules in cold molecular clouds. The most extreme D- and N-15-enrichments are usually observed at the finest spatial scales (0.5-2 microns) that can be measured. These observations suggest that D and N-15 hotspots are in fact preserved nuggets of molecular cloud material, and that the materials within them also have presolar origins. The advanced capabilities of the NanoSIMS ion microprobe now enable us to test this hypothesis. Here, we report two recent examples of presolar silicates found to be directly associated with molecular cloud material.

  10. Element Mapping in Anhydrous IDPs: Identification of the Host Phases of Major/Minor Elements as a Test of Nebula Condensation Models

    NASA Technical Reports Server (NTRS)

    Flynn, G. J.; Keller, L. P.; Wirick, S.; Jacobsen, C.

    2004-01-01

    Many anhydrous interplanetary dust particles (IDPs) are the most pristine samples of primitive solar system dust currently available for laboratory analysis. Their primitive nature is demonstrated by: 1) the high content of moderately volatile elements, indicating they have not been heated significantly since formation, 2) the absence of hydrated material, indicating they never experienced aqueous processing, 3) the presence of unequilibrated mineral assemblages, 4) the presence of large isotopic anomalies (e.g., D and 15N enrichment), in these IDPs.

  11. N-15-Rich Organic Globules in a Cluster IDP and the Bells CM2 Chondrite

    NASA Technical Reports Server (NTRS)

    Messenger, S.; Nakamura-Messenger, K.; Keller, Lindsay P.

    2008-01-01

    Organic matter in primitive meteorites and chondritic porous interplanetary dust particles (CP IDPs) is commonly enriched in D/H and 15N/14N relative to terrestrial values [1-3]. These anomalies are ascribed to the partial preservation of presolar cold molecular cloud material [1]. Some meteorites and IDPs contain m-size inclusions with extreme H and N isotopic anomalies [2-4], possibly due to preserved pristine primordial organic grains. We recently showed that the in the Tagish Lake meteorite, the principle carriers of these anomalies are sub- m, hollow organic globules [5]. The globules likely formed by photochemical processing of organic ices in a cold molecular cloud or the outermost regions of the protosolar disk [5]. We proposed that similar materials should be common among primitive meteorites, IDPs, and comets. Similar objects have been observed in organic extracts of carbonaceous chondrites [6-8], however their N and H isotopic compositions are generally unknown. Bulk H and N isotopic compositions may indicate which meteorites best preserve interstellar organic compounds. Thus, we selected the Bells CM2 carbonaceous chondrites for study based on its large bulk 15N (+335 %) and D (+990 %) [9].

  12. Amorphous Silicates in Primitive Meteoritic Materials: Acfer 094 and IDPs

    NASA Technical Reports Server (NTRS)

    Keller, L. P.; Nakamura-Messenger, K.; Messenger, S.; Walker, Robert M.

    2009-01-01

    The abundance of presolar grains is one measure of the primitive nature of meteoritic materials. Presolar silicates are abundant in meteorites whose matrices are dominated by amorphous silicates such as the unique carbonaceous chondrite Acfer 094. Presolar silicates are even more abundant in chondritic-porous interplanetary dust particles (CP-IDPs). Amorphous silicates in the form of GEMS (glass with embedded metal and sulfides) grains are a major component of CP IDPs. We are studying amorphous silicates in Acfer 094 matrix in order to determine whether they are related to the GEMS grains in CPIDPs

  13. Neural signature of the conscious processing of auditory regularities

    PubMed Central

    Bekinschtein, Tristan A.; Dehaene, Stanislas; Rohaut, Benjamin; Tadel, François; Cohen, Laurent; Naccache, Lionel

    2009-01-01

    Can conscious processing be inferred from neurophysiological measurements? Some models stipulate that the active maintenance of perceptual representations across time requires consciousness. Capitalizing on this assumption, we designed an auditory paradigm that evaluates cerebral responses to violations of temporal regularities that are either local in time or global across several seconds. Local violations led to an early response in auditory cortex, independent of attention or the presence of a concurrent visual task, whereas global violations led to a late and spatially distributed response that was only present when subjects were attentive and aware of the violations. We could detect the global effect in individual subjects using functional MRI and both scalp and intracerebral event-related potentials. Recordings from 8 noncommunicating patients with disorders of consciousness confirmed that only conscious individuals presented a global effect. Taken together these observations suggest that the presence of the global effect is a signature of conscious processing, although it can be absent in conscious subjects who are not aware of the global auditory regularities. This simple electrophysiological marker could thus serve as a useful clinical tool. PMID:19164526

  14. Test and Evaluation of ff99IDPs Force Field for Intrinsically Disordered Proteins.

    PubMed

    Ye, Wei; Ji, Dingjue; Wang, Wei; Luo, Ray; Chen, Hai-Feng

    2015-05-26

    Over 40% of eukaryotic proteomic sequences have been predicted to be intrinsically disordered proteins (IDPs) or intrinsically disordered regions (IDRs) and confirmed to be associated with many diseases. However, widely used force fields cannot well reproduce the conformers of IDPs. Previously the ff99IDPs force field was released to simulate IDPs with CMAP energy corrections for the eight disorder-promoting residues. In order to further confirm the performance of ff99IDPs, three representative IDP systems (arginine-rich HIV-1 Rev, aspartic proteinase inhibitor IA3, and α-synuclein) were used to test and evaluate the simulation results. The results show that for free disordered proteins, the chemical shifts from the ff99IDPs simulations are in quantitative agreement with those from reported NMR measurements and better than those from ff99SBildn. Thus, ff99IDPs can sample more clusters of disordered conformers than ff99SBildn. For structural proteins, both ff99IDPs and ff99SBildn can well reproduce the conformations. In general, ff99IDPs can successfully be used to simulate the conformations of IDPs and IDRs in both bound and free states. However, relative errors could still be found at the boundaries of ordered residues scattered in long disorder-promoting sequences. Therefore, polarizable force fields might be one of the possible ways to further improve the performance on IDPs. PMID:25919886

  15. Sedimentary signatures and processes during marine bolide impacts: a review

    NASA Astrophysics Data System (ADS)

    Dypvik, Henning; Jansa, Lubomir F.

    2003-10-01

    Studies of submarine impact craters resulting from impacts of comets or asteroids demonstrate that the presence of water and the physical properties of target rocks have a major influence on sedimentary processes associated with meteorite impacts. This results in difference in sedimentary signature of bolide impacts in marine environments compared to subaerial impact craters. In subaerial impacts, the targets are commonly hard rocks, frequently of igneous and/or metamorphic origin, whereas in submarine impacts, the targets are mostly unconsolidated or poorly lithified sediments, or sedimentary rocks, with high volumes of pore water. Such differences result in variability in crater morphology and in sedimentary processes inside and outside the impact area. Impacts in shallow-water marine (neritic) environments produced craters with low or absent rims and wide and shallow brims, as characterize by both the Montagnais (on the Scotian shelf), the Mjølnir (in the Barents Sea), 45 and 40 km in diameter, respectively, and the Chesapeake Bay (90 km in diameter). Lack of elevated rims is thought to be the result of current reworking and resurge of the water back into the excavated cavity, as the water in the crater is vaporized. During this process, resurge gullies can be cut across the rim, while mass- and debris-flows, turbidites, and other gravity deposits are produced as results of tsunami and crater-wall and central high collapse, during and after the crater excavation stage. Such deposits are found both within and outside the crater structure. The only difference between gravity deposits triggered by an impact or other rare events, such as earthquakes, is the admixture of various melt particles and possible enrichments in iridium in the former. Impacts near the shelf edge may cause partial collapse of the continental margin as shown by the Montagnais and Chicxulub impacts. Some of the gravity and debris flows generated by margin collapse may be channelized, with

  16. An assessment of the contamination acquired by IDPs during atmospheric deceleration

    NASA Technical Reports Server (NTRS)

    Flynn, George J.

    1994-01-01

    The E-layer of the terrestrial mesosphere, between 80 and 110 km altitude, is derived from meteoric ablation. Concentrations of Na and Fe, contributed by meteoric vapor, have been monitored in the mesosphere, and both individual meteors and average concentration profiles have been measured. Individual interplanetary dust particles (IDP's) entering the earth's atmosphere must pass through the mesospheric layers rich in meteoric volatile elements. Limits on the extent to which individual IDP's can be contaminated by meteoric volatile elements during deceleration in the upper atmosphere can be established by considering the extreme cases: the direct passage of an IDP through a meteoric vapor trail or the passage of an IDP through the mesospheric layer rich in meteoric volatiles. It appears the interaction of IDP's with meteoric vapor during deceleration in the upper atmosphere does not produce significant contamination of IDP's as they decelerate in the upper atmosphere.

  17. An efficient forward-secure group certificate digital signature scheme to enhance EMR authentication process.

    PubMed

    Yu, Yao-Chang; Hou, Ting-Wei

    2014-05-01

    The frequently used digital signature algorithms, such as RSA and the Digital Signature Algorithm (DSA), lack forward-secure function. The result is that, when private keys are renewed, trustworthiness is lost. In other words, electronic medical records (EMRs) signed by revoked private keys are no longer trusted. This significant security threat stands in the way of EMR adoption. This paper proposes an efficient forward-secure group certificate digital signature scheme that is based on Shamir's (t,n) threshold scheme and Schnorr's digital signature scheme to ensure trustworthiness is maintained when private keys are renewed and to increase the efficiency of EMRs' authentication processes in terms of number of certificates, number of keys, forward-secure ability and searching time. PMID:24652661

  18. Comparing Wild 2 Particles to Chondrites and IDPS

    NASA Technical Reports Server (NTRS)

    Zolensky, Michael; Nakamura-Messenger, Keiko; Rietmeijer, Frans; Leroux, Hugues; Mikouchi, Takashi; Ohsumi, Kazumasa; Simon, Steven; Grossman, Lawrence; Stephan, Thomas; Weisberg, Michael; Velbel, Michael; Zega, Thomas; Stroud, Rhonda; Tomeoka, Kazushige; Ohnishi, Ichiro; Tomioka, Naotaka; Nakamura, Tomoki; Matrajt, Graciela; Joswiak, David; Brownlee, Don; Langenhorst, Falko; Krot, Alexander; Kearsley, Anton; Ishii, Hope; Graham, Giles

    2008-01-01

    We compare the observed composition ranges of olivine, pyroxene and Fe-Ni sulfides in Wild 2 grains, comparing these with chondritic IDPs and chondrite classes to explore whether these data suggest affinities to known hydrous materials in particular. Wild 2 olivine has an extremely wide composition range, from Fo4-100 with a pronounced frequency peak at Fo99. The composition range displayed by the low-calcium pyroxene is also very extensive, from En52 to En100, with a significant frequency peak centered at En95. These ranges are as broad or broader than those reported for any other extraterrestrial material. Wild 2 Fe-Ni sulfides mainly have compositions close to that of FeS, with less than 2 atom % Ni - to date, only two pentlandite grains have been found among the Wild-grains suggesting that this mineral is not abundant. The complete lack of compositions between FeS and pentlandite (with intermediate solid solution compositions) suggests (but does not require) that FeS and pentlandite condensed as crystalline species, i.e. did not form as amorphous phases, which later became annealed. While we have not yet observed any direct evidence of water-bearing minerals, the presence of Ni-bearing sulfides, and magnesium-dominated olivine and low-Ca pyroxene does not rule out their presence at low abundance. We do conclude that modern major and minor element compositions of chondrite matrix and IDPs are needed.

  19. IDP Camp and Reconstruction Monitoring Experience at SERTIT

    NASA Astrophysics Data System (ADS)

    Clandillon, Stephen; Allenbach, Bernard; Battiston, Stephanie; Caspard, Mathilde; Fellah, Kader; Giraud, Henri; Montabord, Myldred; Tholey, Nadine; Uribe, Carlos; Yesou, Herve; de Fraipont, Paul

    2010-12-01

    SERTIT's rapid mapping activities covering disasters and damage mapping after a major catastrophic event such as those realized within the framework of International Charter "Space and major disasters" (Charter) and GMES1 programmes are relatively well known, whereas the work carried since 2004 on the exploitation of Earth Observation data for humanitarian aid is less often presented. The aim of this paper is to present this work from mapping and monitoring IDP camp related emergencies to supporting recovery and reconstruction and the context, procedures and examples of this work. A brief introduction to the world of rapid mapping will be given within the context of emergency mapping and monitoring and why this need arises. This is combined with a word on the development of this service with respect to the Internally Displaced Persons (IDP) camp mapping. Then, the cases of Sudan 2004, Chad & Sudan 2008 and Yemen 2009 will be treated to show that the Emergency Mapping and Monitoring Service for Displaced Populations is operational. Afterwards, SERTIT's complementary Emergency Recovery Support Service will be demonstrated through the long- term reconstruction monitoring work carried out, post- disaster, following the 2003 Boumerdès earthquake event. Finally, the need for the availability and deployment of this kind of services is highlighted by the reconstruction planning and monitoring requirements in Haiti, amongst other places.

  20. Geomorphic Processes and Remote Sensing Signatures of Alluvial Fans in the Kun Lun Mountains, China

    NASA Technical Reports Server (NTRS)

    Farr, Tom G.; Chadwick, Oliver A.

    1996-01-01

    The timing of alluvial deposition in arid and semiarid areas is tied to land-surface instability caused by regional climate changes. The distribution pattern of dated deposits provides maps of regional land-surface response to past climate change. Sensitivity to differences in surface roughness and composition makes remote sensing techniques useful for regional mapping of alluvial deposits. Radar images from the Spaceborne Radar Laboratory and visible wavelength images from the French SPOT satellite were used to determine remote sensing signatures of alluvial fan units for an area in the Kun Lun Mountains of northwestern China. These data were combined with field observations to compare surface processes and their effects on remote sensing signatures in northwestern China and the southwestern United States. Geomorphic processes affecting alluvial fans in the two areas include aeolian deposition, desert varnish, and fluvial dissection. However, salt weathering is a much more important process in the Kun Lun than in the southwestern United States. This slows the formation of desert varnish and prevents desert pavement from forming. Thus the Kun Lun signatures are characteristic of the dominance of salt weathering, while signatures from the southwestern United States are characteristic of the dominance of desert varnish and pavement processes. Remote sensing signatures are consistent enough in these two regions to be used for mapping fan units over large areas.

  1. Presolar Materials in a Giant Cluster IDP of Probable Cometary Origin

    NASA Technical Reports Server (NTRS)

    Messenger, S.; Brownlee, D. E.; Joswiak, D. J.; Nguyen, A. N.

    2015-01-01

    Chondritic porous interplanetary dust particles (CP-IDPs) have been linked to comets by their fragile structure, primitive mineralogy, dynamics, and abundant interstellar materials. But differences have emerged between 'cometary' CP-IDPs and comet 81P/Wild 2 Stardust Mission samples. Particles resembling Ca-Al-rich inclusions (CAIs), chondrules, and amoeboid olivine aggregates (AOAs) in Wild 2 samples are rare in CP-IDPs. Unlike IDPs, presolar materials are scarce in Wild 2 samples. These differences may be due to selection effects, such as destruction of fine grained (presolar) components during the 6 km/s aerogel impact collection of Wild 2 samples. Large refractory grains observed in Wild 2 samples are also unlikely to be found in most (less than 30 micrometers) IDPs. Presolar materials provide a measure of primitive-ness of meteorites and IDPs. Organic matter in IDPs and chondrites shows H and N isotopic anomalies attributed to low-T interstellar or protosolar disk chemistry, where the largest anomalies occur in the most primitive samples. Presolar silicates are abundant in meteorites with low levels of aqueous alteration (Acfer 094 approximately 200 ppm) and scarce in altered chondrites (e.g. Semarkona approximately 20 ppm). Presolar silicates in minimally altered CP-IDPs range from approximately 400 ppm to 15,000 ppm, possibly reflecting variable levels of destruction in the solar nebula or statistical variations due to small sample sizes. Here we present preliminary isotopic and mineralogical studies of a very large CP-IDP. The goals of this study are to more accurately determine the abundances of presolar components of CP-IDP material for comparison with comet Wild 2 samples and meteorites. The large mass of this IDP presents a unique opportunity to accurately determine the abundance of pre-solar grains in a likely cometary sample.

  2. Infrared Signature Analysis: Real Time Monitoring Of Manufacturing Processes

    NASA Astrophysics Data System (ADS)

    Bangs, Edmund R.

    1988-01-01

    The ability to monitor manufacturing processes in an adaptive control mode and perform an inspection in real time is of interest to fabricators in the pressure vessel, aerospace, automotive, nuclear and shipbuilding industries. Results of a series of experiments using infrared thermography as the principal sensing mode are presented to show how artificial intelligence contained in infrared isotherm, contains vast critical process variables. Image processing computer software development has demonstrated in a spot welding application how the process can be monitored and controlled in real time. The IR vision sensor program is now under way. Research thus far has focused on fusion welding, resistance spot welding and metal removal.

  3. Nano-Diamonds in Interplanetary Dust Particles (IDPs), Micrometeorites, and Meteorites

    NASA Technical Reports Server (NTRS)

    Dai, Z. R.; Bradley, J. P.; Joswiak, D. J.; Brownlee, D. E.; Genge, M. J.

    2002-01-01

    Nano-diamonds have been identified in IDPs (Interplanetary Dust Particles), micrometeorites, and meteorites. They appear to be depleted in non-cluster IDPs suggesting that some nano-diamonds are not presolar. Additional information is contained in the original extended abstract.

  4. Spatially Resolved Analysis of Amines Using a Fluorescence Molecular Probe: Molecular Analysis of IDPs

    NASA Technical Reports Server (NTRS)

    Clemett, S. J.; Messenger, S.; Thomas-Keprta, K. L.; Wentworth, S. J.; Robinson, G. A.; McKay, D. S.

    2002-01-01

    Some Interplanetary Dust Particles (IDPs) have large isotope anomalies in H and N. To address the nature of the carrier phase, we are developing a procedure to spatially resolve the distribution of organic species on IDP thin sections utilizing fluorescent molecular probes. Additional information is contained in the original extended abstract.

  5. Signature of transient boundary layer processes observed with Viking

    SciTech Connect

    Woch, J.; Lundin, R. )

    1992-02-01

    Transient penetration of plasma with magnetosheath origin is frequently observed with the hot plasma experiment on board the Viking satellite at auroral latitudes in the dayside magnetosphere. The injected magnetosheath ions exhibit a characteristic pitch angle/energy dispersion pattern earlier reported for solar wind ions accessing the magnetosphere in the cusp regions. In contrast to the continuous plasma entry in the cusp, the events discussed here show temporal features which suggest a connection to transient processes at or in the vicinity of the magnetospheric boundary. A single event study confirms previously published observations that the injected ions flow essentially tailward with a velocity comparable to the magnetosheath flow and that the energy spectra inferred for the source population resemble magnetosheath spectra. Based on a statistical study, it is found that these events are predominantly observed around 0800 and 1600 MLT, in a region populated by both rung current/plasma sheet particles and by particles whose source is the magnetosheath plasma. Magnetic field line tracing based on the Tsyganenko magnetic field model yields a scatter of the source locations around the mid-latitude region of the magnetospheric boundary. The probability for these events to occur is highest when the interplanetary magnetic field (IMF) is confined to the ecliptic plane. The connection of the events to transient impulsive solar wind/magnetosphere interaction processes, such as transient reconnection (FTE), impulsive plasma transfer, Kelvin Helmholtz instabilities, and solar wind pressure pulses, is discussed. A relation with transient reconnection can be excluded.

  6. Exploring the geophysical signatures of microbial processes in the earth

    SciTech Connect

    Slater, L.; Atekwana, E.; Brantley, S.; Gorby, Y.; Hubbard, S. S.; Knight, R.; Morgan, D.; Revil, A.; Rossbach, S.; Yee, N.

    2009-05-15

    AGU Chapman Conference on Biogeophysics; Portland, Maine, 13-16 October 2008; Geophysical methods have the potential to detect and characterize microbial growth and activity in subsurface environments over different spatial and temporal scales. Recognition of this potential has resulted in the development of a new subdiscipline in geophysics called 'biogeophysics,' a rapidly evolving Earth science discipline that integrates environmental microbiology, geomicrobiology, biogeochemistry, and geophysics to investigate interactions that occur between the biosphere (microorganisms and their products) and the geosphere. Biogeophysics research performed over the past decade has confirmed the potential for geophysical techniques to detect microbes, microbial growth/biofilm formation, and microbe-mineral interactions. The unique characteristics of geophysical data sets (e.g., noninvasive data acquisition, spatially continuous properties retrieved) present opportunities to explore geomicrobial processes outside of the laboratory, at unique spatial scales unachievable with microbiological techniques, and possibly in remote environments such as the deep ocean. In response to this opportunity, AGU hosted a Chapman Conference with a mission to bring together geophysicists, biophysicists, geochemists, geomicrobiologists, and environmental microbiologists conducting multidisciplinary research with potential impact on biogeophysics in order to define the current state of the science, identify the critical questions facing the community, and generate a road map for establishing biogeophysics as a critical subdiscipline of Earth science research. For more information on the conference, see http://www.agu.org/meetings/chapman/2008/fcall/.

  7. Atypical spatiotemporal signatures of working memory brain processes in autism.

    PubMed

    Urbain, C M; Pang, E W; Taylor, M J

    2015-01-01

    Working memory (WM) impairments may contribute to the profound behavioural manifestations in children with autism spectrum disorder (ASD). However, previous behavioural results are discrepant as are the few functional magnetic resonance imaging (fMRI) results collected in adults and adolescents with ASD. Here we investigate the precise temporal dynamics of WM-related brain activity using magnetoencephalography (MEG) in 20 children with ASD and matched controls during an n-back WM task across different load levels (1-back vs 2-back). Although behavioural results were similar between ASD and typically developing (TD) children, the between-group comparison performed on functional brain activity showed atypical WM-related brain processes in children with ASD compared with TD children. These atypical responses were observed in the ASD group from 200 to 600 ms post stimulus in both the low- (1-back) and high- (2-back) memory load conditions. During the 1-back condition, children with ASD showed reduced WM-related activations in the right hippocampus and the cingulate gyrus compared with TD children who showed more activation in the left dorso-lateral prefrontal cortex and the insulae. In the 2-back condition, children with ASD showed less activity in the left insula and midcingulate gyrus and more activity in the left precuneus than TD children. In addition, reduced activity in the anterior cingulate cortex was correlated with symptom severity in children with ASD. Thus, this MEG study identified the precise timing and sources of atypical WM-related activity in frontal, temporal and parietal regions in children with ASD. The potential impacts of such atypicalities on social deficits of autism are discussed. PMID:26261885

  8. Magnetic Signatures of Fine-scale Processes in the Ocean Surface Layer

    NASA Astrophysics Data System (ADS)

    Soloviev, A.; Dean, C.; Avera, W. E.

    2015-12-01

    Fine-scale processes in the upper ocean turbulent boundary layer may have a measurable electromagnetic signature. In order to study magnetic signatures of these fine-scale processes, we have applied a magnetohydrodynamic (MHD) model combining a 3D computational fluid dynamics model and electromagnetic block, based on ANSYS Fluent software. In addition, the hydrodynamic component of the MHD model is coupled with a radar imaging algorithm, which potentially provides a link to synthetic aperture radar (SAR) satellite imagery. Capabilities of this model have been demonstrated using a simulation and observation of an internal wave soliton in the Straits of Florida, observed with in situ instrumentation (ADCP mooring) and COSMO Sky Med (SAR) satellite image. We have applied this model to study magnetic signatures of surface waves, freshwater lenses, spatially coherent organized motions in the near-surface layer of the ocean (Langmuir circulation and ramp-like structures), and bio-turbulence induced by diel vertical migrations of zooplankton in some areas of the ocean. Investigation of electromagnetic signatures in upper ocean processes offers a valuable new prospect in air-sea interaction.

  9. Comprehensive Study of Hydrated IDPs: X-Ray Diffraction, IR Spectroscopy and Electron Microscopic Analysis

    NASA Technical Reports Server (NTRS)

    Nakamura, K.; Keller, L. P.; Nakamura, T.; Noguchi, T.; Nozaki, W.; Tomeoka, K.

    2003-01-01

    Chondritic hydrated interplanetary dust particles (IDPs) comprise up to 50% of all IDPs collected in the stratosphere(1). Although much is known about the mineralogy, chemistry and carbon abundance of hydrated IDPs (2-4) controversies still exist regarding their formation, history, and relationship to other primitive solar system materials. Hydrated IDPs are generally believed to be derived from asteroidal sources that have undergone some degree of aqueous alteration. However, the high C contents of hydrated IDPs (by 2 to 6X CI levels (3,4) indicate that they are probably not derived from the same parent bodies sampled by the known chondritic meteorites. We report the comprehensive study of individual hydrated IDPs. The strong depletion in Ca (I) has been used as a diagnostic feature of hydrated IDPs. The particles are embedded in elemental sulfur or low viscosity epoxy and ultramicrotomed thin sections are observed using a transmission electron microscope (TEM) equipped with an energy-dispersive X-ray detector (EDX) followed by other measurements including: 1) FTIR microspectroscopy to understand the significant constraints on the organic functionality and the nature of the C-bearing phases and 2) powder X-ray difiaction using a synchrotron X-ray source to understand the bulk mineralogy of the particles.

  10. Natural Radionuclides and Isotopic Signatures for Determining Carbonaceous Aerosol Sources, Aerosol Lifetimes, and Washout Processes

    SciTech Connect

    Gaffney, Jeffrey

    2012-12-12

    This is the final technical report. The project description is as follows: to determine the role of aerosol radiative forcing on climate, the processes that control their atmospheric concentrations must be understood, and aerosol sources need to be determined for mitigation. Measurements of naturally occurring radionuclides and stable isotopic signatures allow the sources, removal and transport processes, as well as atmospheric lifetimes of fine carbonaceous aerosols, to be evaluated.

  11. Technology Gap Analysis for the Detection of Process Signatures Using Less Than Remote Methods

    SciTech Connect

    Hartman, John S.; Atkinson, David A.; Lind, Michael A.; Maughan, A. D.; Kelly, James F.

    2005-01-01

    Although remote sensing methods offer advantages for monitoring important illicit process activities, remote and stand-off technologies cannot successfully detect all important processes with the sensitivity and certainty that is desired. The main scope of the program is observables, with a primary focus on chemical signatures. A number of key process signatures elude remote or stand-off detection for a variety of reasons (e.g., heavy particulate emissions that do not propagate far enough for detection at stand-off distances, semi-volatile chemicals that do not tend to vaporize and remain in the environment near the source, etc.). Some of these compounds can provide persistent, process-specific information that is not available through remote techniques; however, the associated measurement technologies have their own set of advantages, disadvantages and technical challenges that may need to be overcome before additional signature data can be effectively and reliably exploited. The main objective of this report is to describe a process to identify high impact technology gaps for important less-than-remote detection applications. The subsequent analysis focuses on the technology development needed to enable exploitation of important process signatures. The evaluation process that was developed involves three interrelated and often conflicting requirements generation activities: • Identification of target signature chemicals with unique intelligence value and their associated attributes as mitigated by environmentally influenced fate and transport effects (i.e., what can you expect to actually find that has intelligence value, where do you need to look for it and what sensitivity and selectivity do you need to see it) • Identification of end-user deployment scenario possibilities and constraints with a focus on alternative detection requirements, timing issues, logistical consideration, and training requirements for a successful measurement • Identification of

  12. Search for rare SM processes in the MET+b-jets signature at CDF

    SciTech Connect

    Potamianos, Karolos

    2011-05-01

    The missing transverse energy (E{sub T}) plus b-jets signature is very promising for searches for the Higgs boson or new physics. Indeed, E{sub T} naturally arises from unidentified particles such as neutrinos, neutralinos, gravitons, etc., and b-quarks are the main decay products of a low mass Higgs boson as well as of several exotic particles. The main challenge is to identify and reject the numerous standard model (SM) backgrounds that mimic this signature. This is especially so for QCD multi-jet production, a large background due to mis-measurement (rather than undetectable particles). We present state-of-the-art data-driven and multivariate techniques to characterize and reject this instrumental background. These techniques make analyses in this signature as sensitive as those using lepton identification and allow probing for rare SM processes. We describe searches for electroweak single top production, a part of the observation of single top by CDF, and for a low mass SM Higgs boson, one of the most sensitive among low mass Higgs searches at CDF. We also present a measurement of the top pair cross-section in this signature, and discuss other analyses and future prospects.

  13. Inverse dynamical photon scattering (IDPS): an artificial neural network based algorithm for three-dimensional quantitative imaging in optical microscopy.

    PubMed

    Jiang, Xiaoming; Van den Broek, Wouter; Koch, Christoph T

    2016-04-01

    Inverse dynamical photon scattering (IDPS), an artificial neural network based algorithm for three-dimensional quantitative imaging in optical microscopy, is introduced. Because the inverse problem entails numerical minimization of an explicit error metric, it becomes possible to freely choose a more robust metric, to introduce regularization of the solution, and to retrieve unknown experimental settings or microscope values, while the starting guess is simply set to zero. The regularization is accomplished through an alternate directions augmented Lagrangian approach, implemented on a graphics processing unit. These improvements are demonstrated on open source experimental data, retrieving three-dimensional amplitude and phase for a thick specimen. PMID:27136994

  14. Post-analysis report on Chesapeake Bay data processing. [spectral analysis and recognition computer signature extension

    NASA Technical Reports Server (NTRS)

    Thomson, F.

    1972-01-01

    The additional processing performed on data collected over the Rhode River Test Site and Forestry Site in November 1970 is reported. The techniques and procedures used to obtain the processed results are described. Thermal data collected over three approximately parallel lines of the site were contoured, and the results color coded, for the purpose of delineating important scene constituents and to identify trees attacked by pine bark beetles. Contouring work and histogram preparation are reviewed and the important conclusions from the spectral analysis and recognition computer (SPARC) signature extension work are summarized. The SPARC setup and processing records are presented and recommendations are made for future data collection over the site.

  15. Hydrological signatures of Critical Zone Processes: Developing targets for Critical Zone modeling.

    NASA Astrophysics Data System (ADS)

    Thompson, S. E.; Karst, N.; Dralle, D.

    2015-12-01

    Water fluxes through the Critical Zone (CZ) are ubiquitous, and their behavior has the potential to reveal information about the structure and dynamics of the CZ. Models describing these fluxes implicitly propose hypotheses about the CZ which are encoded in the structure of the models. However, the certainty with which such hypotheses can be tested with observed hydrologic data is challenged by the well-known problem of equifinality - the tendency of multiple models, with very different model structures, to produce equally good representations of observed hydrologic dynamics. The project of modeling the CZ is thus challenged by the need to identify hydrologic signatures that are closely tied to the CZ structure and which could provide a stronger basis for hypothesis testing in model frameworks. Here I present one potential signature based on streamflow recession dynamics and the structure of their variability. Firstly, I present a technique to remove a mathematical artifact that is inherent in power-law representations of streamflow recessions. Secondly, I show that having removed this artifact, intriguing relationships emerge in the recession variability in the rivers near the Eel River Critical Zone Observatory. This relationship is interpreted in terms of how water is partitioned within the CZ. The close relationship between CZ processes and this part of the hydrologic response suggests that co-variation in recession parameters could provide a process-oriented hydrologic signature that CZ models should attempt to emulate.

  16. Potential Signatures of Semi-volatile Compounds Associated With Nuclear Processing

    SciTech Connect

    Probasco, Kathleen M.; Birnbaum, Jerome C.; Maughan, A. D.

    2002-06-01

    Semi-volatile chemicals associated with nuclear processes (e.g., the reprocessing of uranium to produce plutonium for nuclear weapons, or the separation of actinides from processing waste streams), can provide sticky residues or signatures that will attach to piping, ducting, soil, water, or other surface media. Volatile compounds, that are more suitable for electro-optical sensing, have been well studied. However, the semi-volatile compounds have not been well documented or studied. A majority of these semi-volatile chemicals are more robust than typical gaseous or liquid chemicals and can have lifetimes of several weeks, months, or years in the environment. However, large data gaps exist concerning these potential signature compounds and more research is needed to fill these data gaps so that important signature information is not overlooked or discarded. This report investigates key semi-volatile compounds associated with nuclear separations, identifies available chemical and physical properties, and discusses the degradation products that would result from hydrolysis, radiolysis and oxidation reactions on these compounds.

  17. Catastrophic Disruptions or Slow Erosion as the Dominant Mechanism for IDP Production

    NASA Astrophysics Data System (ADS)

    Flynn, G. J.

    1993-07-01

    Evidence from the degree of entry heating [1,2] and solar flare track densities [3] suggests a large fraction of the silicate IDPs recovered from the stratosphere are derived from main-belt asteroidal parent bodies. The two dominant mechanisms by which main-belt asteroids contribute to the interplanetary dust are slow erosion and catastrophic disruption with subsequent comminution of the debris. These mechanisms produce profoundly different IDP populations. If slow erosion dominates, the IDPs sample the diversity of the asteroid population in rough proportion to the surface areas of the individual asteroids [4], although probably modified by fragmentation effects [5]. If catastrophic collisions dominate, the IDPs principlly sample the debris of a few recent disruptions. Comparison of the compositional diversity of the IDP population with that of the main-belt asteroids and with the asteroid families associated with recent disruptions should allow a choice between the two mechanisms. Diversity in the Main-Belt: Reflection spectroscopy indicates that the main-belt asteroids include primitive, metamorphic, and igneous objects showing a great range of compositional diversity within each group [6]. Likely parent bodies for most types of meteorites have been identified in the main-belt, and several types of asteroids remain without analog meteorites [6]. Many of these asteroids have relatively high albedos. Diversity of the IDPs: Both the anhydrous and the hydrated silicate IDPs have high contents of carbon [4,7] and volatiles [8]. Only 4 of 30 silicate IDPs analyzed by [4] and 2 of 11 analyzed by Thomas et al. [7] had C/Si lower than CM meteorites, suggesting that most silicate IDPs are carbonaceous chondrites [4]. The parent bodies of these carbon-rich IDPs are likely to be dark objects. Unless many higher albedo interplanetary particles are hidden among the "terrestrial" dust on the collectors, the silicate IDPs do not sample the higher albedo asteroids in proportion

  18. Geophysical signatures of disseminated iron minerals: A proxy for understanding subsurface biophysicochemical processes

    NASA Astrophysics Data System (ADS)

    Abdel Aal, Gamal Z.; Atekwana, Estella A.; Revil, A.

    2014-09-01

    Previous studies have linked biogeophysical signatures to the presence of iron minerals resulting from distinct biophysicochemical processes. Utilizing geophysical methods as a proxy of such biophysicochemical processes requires an understanding of the geophysical signature of the different iron minerals. Laboratory experiments were conducted to investigate the complex conductivity and magnetic susceptibility signatures of five iron minerals disseminated in saturated porous media under variable iron mineral content and grain size. Both pyrite and magnetite show high quadrature and inphase conductivities compared to hematite, goethite, and siderite, whereas magnetite was the highly magnetic mineral dominating the magnetic susceptibility measurements. The quadrature conductivity spectra of both pyrite and magnetite exhibit a well-defined characteristic relaxation peak below 10 kHz, not observed with the other iron minerals. The quadrature conductivity and magnetic susceptibility of individual and a mixture of iron minerals are dominated and linearly proportional to the mass fraction of the highly conductive (pyrite and magnetite) and magnetic (magnetite) iron minerals, respectively. The quadrature conductivity magnitude increased with decreasing grain size diameter of magnetite and pyrite with a progressive shift of the characteristic relaxation peak toward higher frequencies. The quadrature conductivity response of a mixture of different grain sizes of iron minerals is shown to be additive, whereas magnetic susceptibility measurements were insensitive to the variation in grain size diameters (1-0.075 mm). The integration of complex conductivity and magnetic susceptibility measurements can therefore provide a complimentary tool for the successful investigation of in situ biophysicochemical processes resulting in biotransformation or secondary iron mineral precipitation.

  19. Comparative of signal processing techniques for micro-Doppler signature extraction with automotive radar systems

    NASA Astrophysics Data System (ADS)

    Rodriguez-Hervas, Berta; Maile, Michael; Flores, Benjamin C.

    2014-05-01

    In recent years, the automotive industry has experienced an evolution toward more powerful driver assistance systems that provide enhanced vehicle safety. These systems typically operate in the optical and microwave regions of the electromagnetic spectrum and have demonstrated high efficiency in collision and risk avoidance. Microwave radar systems are particularly relevant due to their operational robustness under adverse weather or illumination conditions. Our objective is to study different signal processing techniques suitable for extraction of accurate micro-Doppler signatures of slow moving objects in dense urban environments. Selection of the appropriate signal processing technique is crucial for the extraction of accurate micro-Doppler signatures that will lead to better results in a radar classifier system. For this purpose, we perform simulations of typical radar detection responses in common driving situations and conduct the analysis with several signal processing algorithms, including short time Fourier Transform, continuous wavelet or Kernel based analysis methods. We take into account factors such as the relative movement between the host vehicle and the target, and the non-stationary nature of the target's movement. A comparison of results reveals that short time Fourier Transform would be the best approach for detection and tracking purposes, while the continuous wavelet would be the best suited for classification purposes.

  20. Statistical signatures of structural organization: The case of long memory in renewal processes

    NASA Astrophysics Data System (ADS)

    Marzen, Sarah E.; Crutchfield, James P.

    2016-04-01

    Identifying and quantifying memory are often critical steps in developing a mechanistic understanding of stochastic processes. These are particularly challenging and necessary when exploring processes that exhibit long-range correlations. The most common signatures employed rely on second-order temporal statistics and lead, for example, to identifying long memory in processes with power-law autocorrelation function and Hurst exponent greater than 1/2. However, most stochastic processes hide their memory in higher-order temporal correlations. Information measures-specifically, divergences in the mutual information between a process' past and future (excess entropy) and minimal predictive memory stored in a process' causal states (statistical complexity)-provide a different way to identify long memory in processes with higher-order temporal correlations. However, there are no ergodic stationary processes with infinite excess entropy for which information measures have been compared to autocorrelation functions and Hurst exponents. Here, we show that fractal renewal processes-those with interevent distribution tails ∝t-α-exhibit long memory via a phase transition at α = 1. Excess entropy diverges only there and statistical complexity diverges there and for all α < 1. When these processes do have power-law autocorrelation function and Hurst exponent greater than 1/2, they do not have divergent excess entropy. This analysis breaks the intuitive association between these different quantifications of memory. We hope that the methods used here, based on causal states, provide some guide as to how to construct and analyze other long memory processes.

  1. Carbon analyses of IDP's sectioned in sulfur and supported on beryllium films

    NASA Technical Reports Server (NTRS)

    Bradley, J. P.; Keller, L.; Thomas, K. L.; Vanderwood, T. B.; Brownlee, D. E.

    1993-01-01

    Carbon is the only major element in interplanetary dust whose abundance, distribution and chemical state are not well understood. Information about carbon could clarify the relationship between the various classes of IDP's, conventional meteorites, and sources (e.g., comets vs. asteroids). To date, the most reliable estimates of C abundance in Interplanetary Dust Particles (IDP's) have been obtained by analyzing particles on thick-flat Be substrates using thin-window energy-dispersive spectroscopy in the SEM. These estimates of C abundance are valid only if C is homogeneously distributed, because detected C x-rays originate from the outer 0.1 micrometers of the particle. An alternative and potentially more accurate method of measuring C abundances is to analyze multiple thin sections (each less than 0.1 less than 0.1 micrometers thick) of IDP's. These efforts however, have been stymied because of a lack of a suitable non-carbonaceous embedding medium and the availability of C-free conductive substrates. We have embedded and thin-sectioned IDP's in glassy sulfur, and transferred the thin sections to Be support films approximately 25 nm thick. The sections were then analyzed in a 200 KeV analytical TEM. S sublimes rapidly under vacuum in the TEM, leaving non-embedded sections supported on Be. Apart from quantitative C (and O) analyses, S sectioning dramatically expands the range of analytical measurements that can be performed on a single IDP.

  2. Igneous processes and dike swarms: Magnetic signatures in the Solar System

    NASA Astrophysics Data System (ADS)

    Purucker, M. E.

    2015-12-01

    Large igneous provinces (LIP) are common in planetary environments: at Mars, Venus, Mercury, Io, and of course the Earth and its Moon. Dike swarms are often associated with LIPs, and are one of the only remaining signatures of a LIP in old, eroded settings. On Earth, dike swarms are often recognized by their magnetic signatures. The World Digital Magnetic Anomaly Map (version 2, 2015) is now based on a higher resolution 5 km grid, so many more dike swarms are apparent. We review this latest compilation. Several new high resolution planetary magnetic data sets have also recently become available, and we review evidence for igneous processes, and dikes, in these new data sets. We also review the prospect for new planetary magnetic data sets that might further elucidate igneous processes. At Mars, for example, we have photogeologic evidence for a host of dike swarms, but because of the high altitude of the magnetic data sets, no magnetic evidence exists. A new technique based on remotely sensing the magnetic field of the atomic Na in micro-meteorite ablation layers offers the promise of improving the spatial resolution by a factor of 2-4 at Mars.

  3. Coordinated Chemical and Isotropic Studies of IDPS: Comparison of Circumstellar and Solar GEMS Grains

    NASA Technical Reports Server (NTRS)

    Keller, L. P.; Messenger, S.

    2007-01-01

    Silicate stardust in IDPs and meteorites include forsterite, amorphous silicates, and GEMS grains [1]. Amorphous presolar silicates are much less abundant than expected based on astronomical models [2], possibly destroyed by parent body alteration. A more accurate accounting of presolar silicate mineralogy may be preserved in anhydrous IDPs. Here we present results of coordinated TEM and isotopic analyses of an anhydrous IDP (L2005AL5) that is comprised of crystalline silicates and sulfides, GEMS grains, and equilibrated aggregates embedded in a carbonaceous matrix. Nanometer-scale quantitative compositional maps of all grains in two microtome thin sections were obtained with a JEOL 2500SE. These sections were then subjected to O and N isotopic imaging with the JSC NanoSIMS 50L. Coordinated high resolution chemical maps and O isotopic com-positions were obtained on 11 GEMS grains, 8 crystalline grains, and 6 equilibrated aggregates.

  4. Diversity and adaptation of shelters in transitional settlements for IDPs in Afghanistan.

    PubMed

    Ashmore, Joseph; Babister, Elizabeth; Corsellis, Tom; Fowler, Jon; Kelman, Ilan; McRobie, Allan; Manfield, Peter; Spence, Robin; Vitale, Antonella; Battilana, Rachel; Crawford, Kate

    2003-12-01

    The diversity of shelters used in transitional settlements for internally displaced persons (IDPs) in Herat, Afghanistan is described. The information is based on a field survey undertaken in March 2002 and highlights the adaptation techniques, which IDPs undertake to improve any provided shelter. Potential areas for improvement are indicated; for example, the possibility for using insulated, demountable liners to prevent cold-related deaths without sacrificing shelter flexibility along with the likely need for better agency coordination of the shelter responses they provide. The wider context in which the technical recommendations would be implemented must also be considered. Such issues include agency resources, political impediments to providing the desired option, and the preference of many IDPs that the best shelter would be their home. PMID:14725087

  5. Nebular and Interstellar Materials in a Giant Cluster IDP of Probable Cometary Origin

    NASA Technical Reports Server (NTRS)

    Messenger, S.; Brownlee, D. E.; Joswiak, D. J.; Nguyen, A. N.

    2015-01-01

    Comets contain a complex mixture of materials with presolar and Solar System origins. Chondritic porous interplanetary dust particles (CP-IDPs) are associated with comets by their fragile nature, unequilibrated anhydrous mineralogy and high abundances of circumstellar grains and isotopically anomalous organic materials. Comet 81P/Wild 2 samples returned by the Stardust spacecraft contain presolar materials as well as refractory 16O-rich Ca-Al-rich inclusion- (CAI), chondrule-, and AOA-like materials. We are conducting coordinated chemical, mineralogical, and isotopic studies of a giant cluster CP-IDP (U2-20-GCA) to determine the proportions of inner Solar System and interstellar materials. We previously found that this IDP contains abundant presolar silicates (approx. 1,800 ppm) and 15N-rich hotspots [6].

  6. Organic Matter from Comet 81p/Wild 2, IDPS and Carbonaceous Meteorites; Similarities and Differences

    SciTech Connect

    Wirick, S.; Flynn, G; Keller, L; Nakamura Messenger, K; Peltzer, C; Jacobsen, C; Sandford, S; Zolensky, M

    2009-01-01

    During preliminary examination of 81P/Wild 2 particles collected by the NASA Stardust spacecraft, we analyzed seven, sulfur embedded and ultramicrotomed particles extracted from five different tracks. Sections were analyzed using a scanning transmission X-ray microscope (SXTM) and carbon X-ray absorption near edge structure (XANES) spectra were collected. We compared the carbon XANES spectra of these Wild 2 samples with a database of spectra on thirty-four interplanetary dust particles (IDPs) and with several meteorites. Two of the particles analyzed are iron sulfides and there is evidence that an aliphatic compound associated with these particles can survive high temperatures. An iron sulfide from an IDP demonstrates the same phenomenon. Another, mostly carbon free containing particle radiation damaged, something we have not observed in any IDPs we have analyzed or any indigenous organic matter from the carbonaceous meteorites, Tagish Lake, Orgueil, Bells and Murchison. The carbonaceous material associated with this particle showed no mass loss during the initial analysis but chemically changed over a period of two months. The carbon XANES spectra of the other four particles varied more than spectra from IDPs and indigenous organic matter from meteorites. Comparison of the carbon XANES spectra from these particles with 1. the carbon XANES spectra from thirty-four IDPs (<15 micron in size) and 2. the carbon XANES spectra from carbonaceous material from the Tagish Lake, Orgueil, Bells, and Murchison meteorites show that 81P/Wild 2 carbon XANES spectra are more similar to IDP carbon XANES spectra then to the carbon XANES spectra of meteorites.

  7. How to Assess the Signature of the Data: Catchments and Aquifers as Input Processing Systems

    NASA Astrophysics Data System (ADS)

    Lischeid, G.

    2010-12-01

    It has been argued recently that hydrological models should not only mimic observed data, but should reproduce the signatures of the data appropriately. However, there is no consent how these signatures could be assessed. In general, hydrological models aim at predicting groundwater head dynamics or hydrograph response to input signals (e.g., groundwater recharge, effective rain), based on information about structural properties of the system, like e.g., transmissivity fields, soil hydraulic conductivity, or size of the catchment water storage. That approach usually faces substantial spatial heterogeneities and nonlinear feedbacks. Here, an alternative approach is suggested for characterizing catchments or aquifers as input signal processing systems. The concept was developed for remote areas where direct anthropogenic effects (groundwater withdrawal, injection wells, etc.), plant water uptake and evaporation from groundwater and streams are negligible. Then, any increase of groundwater head or discharge is related to a corresponding input signal, i.e., groundwater recharge or effective rainfall. That signal propagates through the system and is increasingly attenuated and decelerated with increasing flowpath length. This attenuation differs from simple low-pass-filtering. E.g., different input signals propagate at different velocities, depending on rainfall intensity, antecedent soil moisture, etc. The new approach is based on a principal component analysis of time series of groundwater or lake water level, soil water content, or discharge at different sites. This information is used to for assessing the functional properties of the system rather than its structural heterogeneity at different measurement sites, and to assess first order controls on its spatial patterns. Thus, hydrologic measurements provide a mean to measure the functional properties of the system. It is suggested to use this as signatures of the data. In a next step, model structure can be

  8. C/N and other Elemental Ratios of Chondritic Porous IDPS and a Fluffy Concordia Micrometeorite

    NASA Technical Reports Server (NTRS)

    Smith, T.; Nakamura-Messenger, K.; Messenger, S.; Keller, L. P.; Khodja, H.; Raepsaet, C.; Wirick, S.; Flynn, G. J.; Taylor, S.; Engrand, C.; Duprat, J.; Herzog, G. F.

    2013-01-01

    Chondritic porous interplanetary dust particles (CP-IDPs) may be cometary in origin [1], as may ultracarbona-ceous (UCAMMs) [2] and 'fluffy' [3] micrometeorites from the Concordia collection. They are all rich in organics, which can rim grains and may have helped glue grains together during accretion [4]. The organics also contain nitrogen the input of which to Earth has potential biological importance. We report C/N ratios, and other properties of CP-IDPs and a Concordia fluffy microme-teorite.

  9. The molecular signature of AML mesenchymal stromal cells reveals candidate genes related to the leukemogenic process.

    PubMed

    Binato, Renata; de Almeida Oliveira, Nathalia Correa; Du Rocher, Barbara; Abdelhay, Eliana

    2015-12-01

    Acute myeloid leukemia (AML) is a heterogeneous disease characterized by myeloid precursor proliferation in the bone marrow, apoptosis reduction and differentiation arrest. Although there are several studies in this field, events related to disease initiation and progression remain unknown. The malignant transformation of hematopoietic stem cells (HSC) is thought to generate leukemic stem cells, and this transformation could be related to changes in mesenchymal stromal cell (hMSC) signaling. Thus, the aim of this work was to analyze the gene expression profile of hMSC from AML patients (hMSC-AML) compared to healthy donors hMSCs (hMSC-HD). The results showed a common molecular signature for all hMSC-AML. Other assays were performed with a large number of patients and the results confirmed a molecular signature that is capable of distinguishing hMSC-AML from hMSC-HD. Moreover, CCL2 and BMP4 genes encode secreted proteins that could affect HSCs. To verify whether these proteins are differentially expressed in AML patients, ELISA was performed with plasma samples. CCL2 and BMP4 proteins are differentially expressed in AML patients, indicating changes in hMSC-AML signaling. Altogether, hMSCs-AML signaling alterations could be an important factor in the leukemic transformation process. PMID:26279521

  10. Using Bathymodiolus tissue stable isotope signatures to infer biogeochemical process at hydrocarbon seeps

    NASA Astrophysics Data System (ADS)

    Feng, D.; Kiel, S.; Qiu, J.; Yang, Q.; Zhou, H.; Peng, Y.; Chen, D.

    2015-12-01

    Here we use stable isotopes of carbon, nitrogen and sulfur in the tissue of two bathymodiolin mussel species with different chemotrophic symbionts (methanotrophs in B. platifrons and sulfide-oxidizers in B. aduloides) to gain insights into the biogeochemical processes at an active site in 1120 m depth on the Formosa Ridge, called Site F. Because mussels with methanotrophic symbionts acquire the isotope signature of the used methane, the average δ13C values of B. platifrons (-70.3‰; n=36) indicates a biogenic methane source at Site F, consistent with the measured carbon isotope signature of methane (-61.1‰ to -58.7‰) sampled 1.5 m above the mussel beds. The only small offset between the δ13C signatures of the ascending methane and the authigenic carbonate at site F (as low as -55.3‰) suggests only minor mixing of the pore water with marine bicarbonate, which in turn may be used as an indicator for advective rather than diffusive seepage at this site. B. aduloides has much higher average δ13C values of -34.4‰ (n=9), indicating inorganic carbon (DIC) dissolved in epibenthic bottom water as its main carbon source. The DIC was apparently marine bicarbonate with a small contribution of 13C-depleted carbon from locally oxidized methane. The δ34S values of the two mussel species indicate that they used two different sulfur sources. B. platifrons (average δ34S = +6.4±2.6‰; n=36) used seawater sulfate mixed with isotopically light re-oxidized sulfide from the sulfate-dependent anaerobic oxidation of methane (AOM), while the sulfur source of B. aduloides (δ34S = -8.0±3.1‰; n=9) was AOM-derived sulfide used by its symbionts. δ15N values differed between the mussels, with B. platifrons having a wider range of on average slightly lower values (mean = +0.5±0.7‰, n=36) than B. aduloides (mean = +1.1±0.0‰). These values are significantly lower than δ15N values of South China Sea deep-sea sediments (+5‰ to +6‰), indicating that the organic nitrogen

  11. Crustal processes cause adakitic chemical signatures in syn-collision magmatism from SE Iran

    NASA Astrophysics Data System (ADS)

    Allen, Mark; Kheirkhah, Monireh; Neill, Iain

    2015-04-01

    Dehaj magmatism may have developed its geochemical signature during deep fractionation as the ascent of the magmas was impeded by thick orogenic crust. The rocks may be seen as just another part of the widespread syn-collision magmatism that has affected widespread areas of Turkey, Iran, Armenia and neighbouring countries in the last ~10-15 Ma, and need not be used as markers for debateable geodynamic events such as break-off. Adakites are also present in NE Iran without any obvious association with subduction processes. We argue that magmatism across much of the plateau is linked at least in part to mantle upwelling following Miocene slab break-off, but also to small-scale convection beneath the collision zone, as predicted by numerical modelling. Particular compositions such as those at Dehaj are influenced by local sources and differentiation processes, but there is no need for independent triggers for initial melting across disparate locations.

  12. From Positivity to Negativity Bias: Ambiguity Affects the Neurophysiological Signatures of Feedback Processing.

    PubMed

    Gibbons, Henning; Schnuerch, Robert; Stahl, Jutta

    2016-04-01

    Previous studies on the neurophysiological underpinnings of feedback processing almost exclusively used low-ambiguity feedback, which does not fully address the diversity of situations in everyday life. We therefore used a pseudo trial-and-error learning task to investigate ERPs of low- versus high-ambiguity feedback. Twenty-eight participants tried to deduce the rule governing visual feedback to their button presses in response to visual stimuli. In the blocked condition, the same two feedback words were presented across several consecutive trials, whereas in the random condition feedback was randomly drawn on each trial from sets of five positive and five negative words. The feedback-related negativity (FRN-D), a frontocentral ERP difference between negative and positive feedback, was significantly larger in the blocked condition, whereas the centroparietal late positive complex indicating controlled attention was enhanced for negative feedback irrespective of condition. Moreover, FRN-D in the blocked condition was due to increased reward positivity (Rew-P) for positive feedback, rather than increased (raw) FRN for negative feedback. Our findings strongly support recent lines of evidence that the FRN-D, one of the most widely studied signatures of reinforcement learning in the human brain, critically depends on feedback discriminability and is primarily driven by the Rew-P. A novel finding concerned larger frontocentral P2 for negative feedback in the random but not the blocked condition. Although Rew-P points to a positivity bias in feedback processing under conditions of low feedback ambiguity, P2 suggests a specific adaptation of information processing in case of highly ambiguous feedback, involving an early negativity bias. Generalizability of the P2 findings was demonstrated in a second experiment using explicit valence categorization of highly emotional positive and negative adjectives. PMID:26765948

  13. Deciphering seismic signatures of physical processes in dynamic complex systems: an experimental approach

    NASA Astrophysics Data System (ADS)

    Arciniega-Ceballos, A.; Alatorre-Ibarguengoitia, M. A.; Perton, M.; Sanchez-Sesma, F. J.; Dingwell, D. B.

    2012-12-01

    Seismic evaluation of well-controlled experimental simulations of volumetric sources (e.g. explosions, cavitations, burst, pressure drops) is a powerful tool for better understanding of the seismic wave field of complex systems. In this work, we describe two distinct well-constrained physical models, which under controlled laboratory conditions enable the simulation of complex systems; volcanic explosions and fluid-filled wells. For volcanic explosion simulations, several experiments were performed to study seismic signals associated with fragmentation processes of volcanic rocks by rapid decompression. These experiments were performed in a shock-tube apparatus at room temperature and a pressure range of 4 to 20 MPa. Pumice samples from Popocatepetl volcano of different porosity were studied. To investigate the elastic wave propagation inside a fluid-filled well, we present a hollow cylinder model surrounded by water, excited by a ultrasonic laser beam emitting pulses between 5 and 8 ns in duration, causing micro-cavitations. Adequate instrumentation of these mechanical systems, using high-precision sensors, enabled us to capture and to analyze seismic wave fields, characterizing also their source mechanism. Although these laboratory analogues have simplified geometries and media properties, these experimental investigations are based upon the hypothesis that, in comparable systems, any physical process (e.g. pressure drops, fragmentation, vibration, elastic deformation, etc) conducts to equivalent system responses, causing the same distinctive effects, which are independent on the scale. These effects engender particular seismic signatures, reflecting the dynamics of the process, and are comparable with numerical simulations and seismic field observations. Therefore, laboratory models can validate the inverse problem solution, indicating that the source mechanism and the system nature can both be inferred from field-based seismograms.

  14. Extraction of Helium from Individual IDPs and Lunar Grains by Pulse Heating

    NASA Astrophysics Data System (ADS)

    Nier, A. O.; Schlutter, D. J.

    1992-07-01

    We have reported on the extraction of helium and neon from individual IDPs by step-heating (1,2). The purpose of the study was to see if differences in release patterns existed which might shed light on the heating experienced by the particles in their deceleration during descent in the Earth's upper atmosphere. Flynn (3), as well as earlier investigators, has shown that dust particles originating in high perihelia comets or in asteroids would, in general, have less energy and hence are heated less than low perihelia comets. In a study of 20 particles (2) it was found that 12 contained an appreciable amount of helium, and this was released in the same general temperature range as found for typical lunar grains. Four particles contained considerably less helium, and this was released at a higher temperature. The remaining particles contained essentially no helium. In a more recent study, fragments of 12 IDPs were investigated as a part of a coordinated investigation. Other fragments of the same IDPs are being examined for elemental and mineralogical content by other investigators. In the new work (4) the gas is extracted by a succession of 5-second constant-power pulses of increasing power, closely resembling the heat pulses experienced by IDPs in their deceleration in the atmosphere (5). The amount of gas removed is studied as a function of the peak temperature reached in the individual pulses. Flynn and Sutton (6) and Flynn et al. (7), using Transmission Electron Microscopy (TEM) and Synchrotron X-ray Fluorescence (SXRF) for trace element analyses, have reported low zinc abundances in some IDPs. They believe the low abundance could be due to the loss of volatile elements through heating during the deceleration of the particles during atmospheric entry. In our present study, low amounts of helium were found in fragments which were parts of the same IDPs as the fragments for which low Zn concentrations were found (G. Flynn, private communication). Whether the effect

  15. Voyager 2 Signatures of Important Processes/Dynamics in the Outer Heliosphere

    NASA Astrophysics Data System (ADS)

    Intriligator, D. S.; Intriligator, J.; Miller, W. D.; Webber, W. R.; Decker, R. B.; Sittler, E. C.

    2011-12-01

    We continue investigating the Voyager 2 (V2) Plasma Subsystem (PLS) elevated readings in L-mode on energy/unit charge (E/Q) step 12 on the B-Cup we first reported (Intriligator et al., JGR, 2010) near the termination shock at 84 AU. These elevated B12 readings, which we previously referred to as "high energy ions (HEIs)", are found in the V2 PLS data on the sunward facing B-Cup at E/Q step 12 corresponding to 1610 volts and a proton speed of ~ 600 km/s. In the present paper we update our findings and present V2 data from three years earlier when V2 was in the solar wind in the outer heliosphere (OH) at 73 AU measuring the interplanetary (IP) effects from the October-November (Halloween) 2003 solar events. We also examine other V2 OH time intervals. We show links between solar activity and the elevated B12 readings in the V2 data. We present evidence that these elevated B12 readings appear to be accompanied by significant simultaneous changes in other V2 measurements, including: low energy ions, low energy cosmic rays, anomalous cosmic rays, cosmic ray electrons, interplanetary magnetic field (IMF), and convective solar wind plasma. Our results suggest that the V2 elevated B12 readings may be signatures, tracers, by-products, or indicators of important IP processes such as those associated with intervals of particle acceleration, changes in IMF turbulence, and perhaps local reconnection. This work was funded by NASA Grant NNX08AE40G and by Carmel Research Center, Inc.

  16. Modeling of charge transfer processes to understand photophysical signatures: The case of Rhodamine 110

    NASA Astrophysics Data System (ADS)

    Savarese, Marika; Raucci, Umberto; Netti, Paolo A.; Adamo, Carlo; Ciofini, Ilaria; Rega, Nadia

    2014-08-01

    Photophysical signatures, namely absorption and emission energies, lifetime and quantum yields, have been computed through TD-DFT approaches and compared with experimental counterparts for the Rhodamine 110 dye in aqueous solution. Thanks to a new protocol of analysis, based on the use of very promising electronic based indices, it has been possible to investigate the interplay between Rhodamine 110 dye's structure, degree of charge transfer upon excitation, and fluorescence signatures. This combined analysis is very promising to support the understanding of charge transfer based mechanisms affecting dyes photophysics.

  17. Signing below the dotted line: signature position as a marker of vulnerability for visuospatial processing difficulties.

    PubMed

    Whitelock, Claire F; Agyepong, Heather Nao; Patterson, Karalyn; Ersche, Karen D

    2015-02-01

    Almost one-third of the participants in a neuropsychological study signed the consent form below the given line. The relationship between a signature position on or below the line and participants' cognitive function was investigated. Fifty drug-dependent individuals, 50 of their siblings, and 50 unrelated control participants completed a battery of neuropsychological tests using the Cambridge Neuropsychological Test Automated Battery (CANTAB). Individuals signing below, rather than on, the line performed more poorly on tests of visuospatial memory, but no differently on other cognitive tests. Signature positioning may be a soft sign for impairment of the mechanisms involved in visuospatial memory. PMID:24313358

  18. Signatures support program

    NASA Astrophysics Data System (ADS)

    Hawley, Chadwick T.

    2009-05-01

    The Signatures Support Program (SSP) leverages the full spectrum of signature-related activities (collections, processing, development, storage, maintenance, and dissemination) within the Department of Defense (DOD), the intelligence community (IC), other Federal agencies, and civil institutions. The Enterprise encompasses acoustic, seismic, radio frequency, infrared, radar, nuclear radiation, and electro-optical signatures. The SSP serves the war fighter, the IC, and civil institutions by supporting military operations, intelligence operations, homeland defense, disaster relief, acquisitions, and research and development. Data centers host and maintain signature holdings, collectively forming the national signatures pool. The geographically distributed organizations are the authoritative sources and repositories for signature data; the centers are responsible for data content and quality. The SSP proactively engages DOD, IC, other Federal entities, academia, and industry to locate signatures for inclusion in the distributed national signatures pool and provides world-wide 24/7 access via the SSP application.

  19. Neural Signatures of Number Processing in Human Infants: Evidence for Two Core Systems Underlying Numerical Cognition

    ERIC Educational Resources Information Center

    Hyde, Daniel C.; Spelke, Elizabeth S.

    2011-01-01

    Behavioral research suggests that two cognitive systems are at the foundations of numerical thinking: one for representing 1-3 objects in parallel and one for representing and comparing large, approximate numerical magnitudes. We tested for dissociable neural signatures of these systems in preverbal infants by recording event-related potentials…

  20. 78 FR 43145 - Announcing Approval of Federal Information Processing Standard 186-4, Digital Signature Standard

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-19

    ... develop computer security standards to protect federal sensitive (unclassified) information systems are..., first published on May 19, 1994 (59 FR 26208), specified a digital signature algorithm (DSA) to generate... Register on December 15, 1998 (63 FR 69049) and FIPS 186-2, which was published on February 15, 2000 (65...

  1. Signature of magmatic processes in ground deformation signals from Phlegraean Fields (Italy)

    NASA Astrophysics Data System (ADS)

    Bagagli, Matteo; Montagna, Chiara Paola; Longo, Antonella; Papale, Paolo

    2016-04-01

    Ground deformation signals such as dilatometric and tiltmetric ones, are nowadays well studied from the vulcanological community all over the world. These signals can be used to retrieve information on volcanoes state and to study the magma dynamics in their plumbing system. We compared synthetic signals in the Very Long Period (VLP, 10‑2 ‑ 10‑1 Hz) and Ultra Long Period (ULP, 10‑4 ‑ 10‑2 Hz) bands obtained from the simulation of magma mixing in shallow reservoirs ([3],[4]) with real data obtained from the dilatometers and tiltmeters network situated in the Phlegraean Fields near Naples (Italy), in order to define and constrain the relationships between them. Analyses of data from the October 2006 seismic swarm in the area show that the frequency spectrum of the synthetics is remarkably similar to the transient present in the real signals. In depth studies with accurated techniques for spectral analysis (i.e wavelet transform) and application of this method to other time windows have identified in the bandwidth around 10‑4Hz (between 1h30m and 2h45m) peaks that are fairly stable and independent from the processing carried out on the full-band signal. These peaks could be the signature of ongoing convection at depth. It is well known that re-injection of juvenile magmas can reactivate the eruption dynamics ([1],[2]), thus being able to define mixing markers and detect them in the ground deformation signals is a relevant topic in order to understand the dynamics of active and quiescent vulcanoes and to eventually improve early-warning methods for impending eruptions. [1] Arienzo, I. et al. (2010). "The feeding system of Agnano-Monte Spina eruption (Campi Flegrei, Italy): dragging the past into present activity and future scenarios". In: Chemical Geology 270.1, pp. 135-147. [2] Bachmann, Olivier and George Bergantz (2008). "The magma reservoirs that feed supereruptions". In: Elements 4.1, pp. 17-21. [3] Longo, Antonella et al. (2012). "Magma convection

  2. Testing the realism of model structures to identify karst system processes using water quality and quantity signatures

    NASA Astrophysics Data System (ADS)

    Hartmann, A.; Wagener, T.; Rimmer, A.; Lange, J.; Brielmann, H.; Weiler, M.

    2012-12-01

    Many hydrological systems exhibit complex subsurface flow and storage behavior. Runoff observations often only provide insufficient information for unique process identification of complex hydrologic systems. Quantitative modeling of water and solute fluxes presents a potentially more powerful avenue to explore whether hypotheses about system functioning can be rejected or conditionally accepted. In this study we developed and tested four hydrological model structures, based on different hypotheses about subsurface flow and storage behavior, to identify the functioning of a large Mediterranean karst system. Using eight different system signatures, i.e. indicators of particular hydrodynamic and hydrochemical characteristics of the karst system, we applied a novel model evaluation strategy to identify the best conceptual model representation of the karst system. Our approach consists of three stages: (1) evaluation of model performance with respect to system signatures using automatic calibration, (2) evaluation of parameter identifiability using Sobol's sensitivity analysis, and (3) evaluation of model plausibility by combining the results of stages (1) and (2). These evaluation stages eliminated three model structures and lead to a unique hypothesis about the functioning of the studied karst system. We used the estimated parameter values to further quantify subsurface processes. The remaining model is able to simultaneously provide high performances for all eight system signatures. Our approach demonstrates the benefits of interpreting different tracers in a hydrologically meaningful way during model evaluation and identification.

  3. Testing the realism of model structures to identify karst system processes using water quality and quantity signatures

    NASA Astrophysics Data System (ADS)

    Hartmann, A.; Wagener, T.; Rimmer, A.; Lange, J.; Brielmann, H.; Weiler, M.

    2013-06-01

    Many hydrological systems exhibit complex subsurface flow and storage behavior. Runoff observations often only provide insufficient information for unique process identification. Quantitative modeling of water and solute fluxes presents a potentially more powerful avenue to explore whether hypotheses about system functioning can be rejected or conditionally accepted. In this study we developed and tested four hydrological model structures, based on different hypotheses about subsurface flow and storage behavior, to identify the functioning of a large Mediterranean karst system. Using eight different system signatures, i.e., indicators of particular hydrodynamic and hydrochemical characteristics of the karst system, we applied a novel model evaluation strategy to identify the best conceptual model representation of the karst system within our set of possible system representations. Our approach to test model realism consists of three stages: (1) evaluation of model performance with respect to system signatures using automatic calibration, (2) evaluation of parameter identifiability using Sobol's sensitivity analysis, and (3) evaluation of model plausibility by combining the results of stages (1) and (2). These evaluation stages eliminated three out of four model structures and lead to a unique hypothesis about the functioning of the studied karst system. We used the estimated parameter values to further quantify subsurface processes. The chosen model is able to simultaneously provide high performances for eight system signatures with realistic parameter values. Our approach demonstrates the benefits of interpreting different tracers in a hydrologically meaningful way during model evaluation and identification.

  4. Methods of extending signatures and training without ground information. [data processing, pattern recognition

    NASA Technical Reports Server (NTRS)

    Henderson, R. G.; Thomas, G. S.; Nalepka, R. F.

    1975-01-01

    Methods of performing signature extension, using LANDSAT-1 data, are explored. The emphasis is on improving the performance and cost-effectiveness of large area wheat surveys. Two methods were developed: ASC, and MASC. Two methods, Ratio, and RADIFF, previously used with aircraft data were adapted to and tested on LANDSAT-1 data. An investigation into the sources and nature of between scene data variations was included. Initial investigations into the selection of training fields without in situ ground truth were undertaken.

  5. Joint-specific DNA methylation and transcriptome signatures in rheumatoid arthritis identify distinct pathogenic processes.

    PubMed

    Ai, Rizi; Hammaker, Deepa; Boyle, David L; Morgan, Rachel; Walsh, Alice M; Fan, Shicai; Firestein, Gary S; Wang, Wei

    2016-01-01

    Stratifying patients on the basis of molecular signatures could facilitate development of therapeutics that target pathways specific to a particular disease or tissue location. Previous studies suggest that pathogenesis of rheumatoid arthritis (RA) is similar in all affected joints. Here we show that distinct DNA methylation and transcriptome signatures not only discriminate RA fibroblast-like synoviocytes (FLS) from osteoarthritis FLS, but also distinguish RA FLS isolated from knees and hips. Using genome-wide methods, we show differences between RA knee and hip FLS in the methylation of genes encoding biological pathways, such as IL-6 signalling via JAK-STAT pathway. Furthermore, differentially expressed genes are identified between knee and hip FLS using RNA-sequencing. Double-evidenced genes that are both differentially methylated and expressed include multiple HOX genes. Joint-specific DNA signatures suggest that RA disease mechanisms might vary from joint to joint, thus potentially explaining some of the diversity of drug responses in RA patients. PMID:27282753

  6. Joint-specific DNA methylation and transcriptome signatures in rheumatoid arthritis identify distinct pathogenic processes

    PubMed Central

    Ai, Rizi; Hammaker, Deepa; Boyle, David L.; Morgan, Rachel; Walsh, Alice M.; Fan, Shicai; Firestein, Gary S.; Wang, Wei

    2016-01-01

    Stratifying patients on the basis of molecular signatures could facilitate development of therapeutics that target pathways specific to a particular disease or tissue location. Previous studies suggest that pathogenesis of rheumatoid arthritis (RA) is similar in all affected joints. Here we show that distinct DNA methylation and transcriptome signatures not only discriminate RA fibroblast-like synoviocytes (FLS) from osteoarthritis FLS, but also distinguish RA FLS isolated from knees and hips. Using genome-wide methods, we show differences between RA knee and hip FLS in the methylation of genes encoding biological pathways, such as IL-6 signalling via JAK-STAT pathway. Furthermore, differentially expressed genes are identified between knee and hip FLS using RNA-sequencing. Double-evidenced genes that are both differentially methylated and expressed include multiple HOX genes. Joint-specific DNA signatures suggest that RA disease mechanisms might vary from joint to joint, thus potentially explaining some of the diversity of drug responses in RA patients. PMID:27282753

  7. Rapid Cenozoic ingrowth of isotopic signatures simulating "HIMU" in ancient lithospheric mantle: Distinguishing source from process

    NASA Astrophysics Data System (ADS)

    McCoy-West, Alex J.; Bennett, Vickie C.; Amelin, Yuri

    2016-08-01

    Chemical and isotopic heterogeneities in the lithospheric mantle are increasingly being recognised on all scales of examination, although the mechanisms responsible for generating this variability are still poorly understood. To investigate the relative behaviour of different isotopic systems in off-cratonic mantle, and specifically the origin of the regional southwest Pacific "HIMU" (high time integrated 238U/204Pb) Pb isotopic signature, we present the first U-Th-Pb, Rb-Sr, Sm-Nd and Re-Os isotopic dataset for spinel peridotite xenoliths sampling the subcontinental lithospheric mantle (SCLM) beneath Zealandia. Strongly metasomatised xenoliths converge to a restricted range of Sr and Nd isotopic compositions (87Sr/86Sr = 0.7028-0.7033; εNd ≈ +3-+6) reflecting pervasive overprinting of their original melt depletion signatures by carbonatite-rich melts. In contrast, rare, weakly metasomatised samples possess radiogenic Nd isotopic compositions (εNd > +15) and unradiogenic Sr isotopic compositions (87Sr/86Sr < 0.7022). This is consistent with melt extraction at ca. 2.0 Ga and in accord with widespread Paleoproterozoic Re-Os model ages from both weakly metasomatised and the more numerous, strongly metasomatised xenoliths. The coupling of chalcophile (Os), and lithophile (Sr and Nd) melt depletion ages from peridotite xenoliths on a regional scale under Zealandia argues for preservation of a significant mantle keel (⩾2 million km3) associated with a large-scale Paleoproterozoic melting event. Lead isotopic compositions are highly variable with 206Pb/204Pb = 17.3-21.3 (n = 34) and two further samples with more extreme compositions of 22.4 and 25.4, but are not correlated with other isotopic data or U/Pb and Th/Pb ratios in either strongly or weakly metasomatised xenoliths; this signature is thus a recent addition to the lithospheric mantle. Lead model ages suggest that this metasomatism occurred in the last 200 m.y., with errorchrons from individual localities

  8. What does the fine-scale petrography of IDPs reveal about grain formation and evolution in the early solar system?

    NASA Technical Reports Server (NTRS)

    Bradley, John

    1994-01-01

    The 'pyroxene' interplanetary dust particles (IDP's) may be the best samples for investigation of primordial grain-forming reactions because they appear to have experienced negligible post-accretional alteration. They are likely to continue to yield information about gas-to-solid condensation and other grain-forming reactions that may have occurred either in the solar nebular or presolar interstellar environments. An immediate challenge lies in understanding the nanometer-scale petrography of the ultrafine-grained aggregates in 'pyroxene' IDP's. Whether these aggregates contain components from diverse grain-forming environments may ultimately be answered by systematic petrographic studies using electron microscopes capable of high spatial resolution microanalysis. It may be more difficult to decipher evidence of grain formation and evolution in 'olivine' and 'layer silicate' IDP's because they appear to have experienced post-accretional alteration. Most of the studied 'olivine' IDPs have been subjected to heating and equilibration, perhaps during atmospheric entry, while the 'layer silicate' IDP's have experienced aqueous alteration.

  9. Kabrit ki gen twòp mèt: understanding gaps in WASH services in Haiti's IDP camps.

    PubMed

    Schuller, Mark; Levey, Tania

    2014-04-01

    Despite the enormous infusion of post-quake aid to Haiti, cholera had killed more than 8,000 people by January 2013. Based on two mixed-method studies of a random sample of 108 internally displaced person (IDP) camps and 168 interviews with agency representatives and recipients, this article examines the prevalence of factors that have proven most relevant to the rapid spread of cholera, particularly the provision of water and sanitation services in IDP camps. The study reveals that 30% of IDP camps had no toilets and 40% had no access to water before the outbreak, with only minimal progress after three months. Using bivariate and multivariate statistical analyses, this article explores patterns in the gaps of services with a range of variables such as NGO camp management, municipality and land-owners. It offers several theoretical and policy explanations for low level of services, concluding with a series of recommendations for better coordination and management. PMID:24601930

  10. Unusual satellite-electron signature within the Uranian magnetosphere and its implications regarding whistler electron loss processes

    NASA Technical Reports Server (NTRS)

    Mauk, B. H.; Keath, E. P.; Krimigis, S. M.

    1994-01-01

    It has been reported that during the outbound (nightside) portion of the Voyager 2 encounter with the Uranian magnetosphere, intense whistler mode emissions were observed near the magnetic equator (lambda(sub m) approx. 16 deg) and at L shell values between approx. 5.5 and approx. 9 R(sub U). Comprehensive calculations of whistler-driven pitch angle diffusion, in previous work, have yielded strong diffusion electron lifetimes of approx. 1 hour for 20 to 40 keV electrons. In this paper we report on an unusual and sharply defined charged particle feature that: (1) involved electrons between 22 and 35 keV, (2) was observed during the time period of the intense whistler mode observations, (3) was aligned very accurately and sharply with the minimum L shell position (L approx. 7.5) of the satellite Ariel, and (4) has an appearance that suggests that electrons were removed only at and beyond Ariel's minimum-L. On the basis of our conclusion that the signature was caused by electron interactions with either Ariel or materials distributed along Ariel's orbit, the signature could not have been generated for at least 10 hours prior to its observation. Thus the calculated whistler loss times are in apparent conflict with the signature observation. A scenario of events is proposed to explain the data that involves substormlike electron acceleration on the Uranian nightside and a subsequent sculpting of the electron spatial distributions via interactions with Ariel or materials distributed along Ariel's orbit. The possibility exists that the accurate alignment of the sharp electron feature with Ariel's minimum-L, and the absorptionlike character of the feature, are accidental, and that the feature is caused by dynamical processes (e.g., substorms). In this case the dynamical processes must be quite dissimilar to those occurring in the Earth's magnetosphere.

  11. Depletions of sulfur and/or zinc in IDPs: Are they reliable indicators of atmospheric entry heating?

    NASA Technical Reports Server (NTRS)

    Flynn, G. J.; Sutton, S. R.; Bajt, S.; Kloeck, W.; Thomas, K. L.; Keller, L. P.

    1993-01-01

    The degree of heating of interplanetary dust particles (IDP's) on Earth atmospheric entry is important in distinguishing cometary particles from main-belt asteroidal particles. Depletions in the volatile elements S and Zn were proposed as chemical indicators of significant entry heating. The S and Zn contents of cosmic dust particles were correlated with physical indicators of atmospheric entry heating, such as the production of magnetite and the loss of solar wind implanted He. The results indicate that the Zn content of IDP's is a useful indicator of entry heating, but the S content seems to be less useful.

  12. Uncertainty in hydrological signatures

    NASA Astrophysics Data System (ADS)

    Westerberg, I. K.; McMillan, H. K.

    2015-09-01

    Information about rainfall-runoff processes is essential for hydrological analyses, modelling and water-management applications. A hydrological, or diagnostic, signature quantifies such information from observed data as an index value. Signatures are widely used, e.g. for catchment classification, model calibration and change detection. Uncertainties in the observed data - including measurement inaccuracy and representativeness as well as errors relating to data management - propagate to the signature values and reduce their information content. Subjective choices in the calculation method are a further source of uncertainty. We review the uncertainties relevant to different signatures based on rainfall and flow data. We propose a generally applicable method to calculate these uncertainties based on Monte Carlo sampling and demonstrate it in two catchments for common signatures including rainfall-runoff thresholds, recession analysis and basic descriptive signatures of flow distribution and dynamics. Our intention is to contribute to awareness and knowledge of signature uncertainty, including typical sources, magnitude and methods for its assessment. We found that the uncertainties were often large (i.e. typical intervals of ±10-40 % relative uncertainty) and highly variable between signatures. There was greater uncertainty in signatures that use high-frequency responses, small data subsets, or subsets prone to measurement errors. There was lower uncertainty in signatures that use spatial or temporal averages. Some signatures were sensitive to particular uncertainty types such as rating-curve form. We found that signatures can be designed to be robust to some uncertainty sources. Signature uncertainties of the magnitudes we found have the potential to change the conclusions of hydrological and ecohydrological analyses, such as cross-catchment comparisons or inferences about dominant processes.

  13. Uncertainty in hydrological signatures

    NASA Astrophysics Data System (ADS)

    Westerberg, I. K.; McMillan, H. K.

    2015-04-01

    Information about rainfall-runoff processes is essential for hydrological analyses, modelling and water-management applications. A hydrological, or diagnostic, signature quantifies such information from observed data as an index value. Signatures are widely used, including for catchment classification, model calibration and change detection. Uncertainties in the observed data - including measurement inaccuracy and representativeness as well as errors relating to data management - propagate to the signature values and reduce their information content. Subjective choices in the calculation method are a further source of uncertainty. We review the uncertainties relevant to different signatures based on rainfall and flow data. We propose a generally applicable method to calculate these uncertainties based on Monte Carlo sampling and demonstrate it in two catchments for common signatures including rainfall-runoff thresholds, recession analysis and basic descriptive signatures of flow distribution and dynamics. Our intention is to contribute to awareness and knowledge of signature uncertainty, including typical sources, magnitude and methods for its assessment. We found that the uncertainties were often large (i.e. typical intervals of ±10-40% relative uncertainty) and highly variable between signatures. There was greater uncertainty in signatures that use high-frequency responses, small data subsets, or subsets prone to measurement errors. There was lower uncertainty in signatures that use spatial or temporal averages. Some signatures were sensitive to particular uncertainty types such as rating-curve form. We found that signatures can be designed to be robust to some uncertainty sources. Signature uncertainties of the magnitudes we found have the potential to change the conclusions of hydrological and ecohydrological analyses, such as cross-catchment comparisons or inferences about dominant processes.

  14. From benchtop to raceway : spectroscopic signatures of dynamic biological processes in algal communities.

    SciTech Connect

    Trahan, Christine Alexandra; Garcia, Omar Fidel; Martino, Anthony A.; Raymer, Michelle; Collins, Aaron M.; Hanson, David T.; Turner, Tom; Powell, Amy Jo; James, Scott Carlton; Timlin, Jerilyn Ann; Scholle, Steven; Dwyer, Brian P.; Ruffing, Anne; Jones, Howland D. T.; Ricken, James Bryce; Reichardt, Thomas A.

    2010-08-01

    The search is on for new renewable energy and algal-derived biofuel is a critical piece in the multi-faceted renewable energy puzzle. It has 30x more oil than any terrestrial oilseed crop, ideal composition for biodiesel, no competition with food crops, can be grown in waste water, and is cleaner than petroleum based fuels. This project discusses these three goals: (1) Conduct fundamental research into the effects that dynamic biotic and abiotic stressors have on algal growth and lipid production - Genomics/Transcriptomics, Bioanalytical spectroscopy/Chemical imaging; (2) Discover spectral signatures for algal health at the benchtop and greenhouse scale - Remote sensing, Bioanalytical spectroscopy; and (3) Develop computational model for algal growth and productivity at the raceway scale - Computational modeling.

  15. Transformation processes, pathways, and possible sources of distinctive polychlorinated dibenzo-p-dioxin signatures in sink environments.

    PubMed

    Gaus, Caroline; Brunskill, Gregg J; Connell, W; Prange, Joelle; Müller, Jochen F; Päpke, Olaf; Weber, Roland

    2002-08-15

    In recent years, studies on environmental samples with unusual dibenzo-p-dioxin (PCDD) congener profiles were reported from a range of countries. These profiles, characterized by a dominance of octachlorinated dibenzodioxin (OCDD) and relatively low in dibenzofuran (PCDF) concentrations, could not be attributed to known sources or formation processes. In the present study, the processes that result in these unusual profiles were assessed using the concentrations and isomer signatures of PCDDs from dated estuarine sediment cores in Queensland, Australia. Increases in relative concentrations of lower chlorinated PCDDs and a relative decrease of OCDD were correlated with time of sediment deposition. Preferred lateral, anaerobic dechlorination of OCDD represents a likely pathway for these changes. In Queensland sediments, these transformations result in a distinct dominance of isomers fully chlorinated in the 1,4,6,9-positions (1,4-patterns), and similar 1,4-patterns were observed in sediments from elsewhere. Consequently, these environmental samples may not reflect the signatures of the original source, and a reevaluation of source inputs was undertaken. Natural formation of PCDDs, which has previously been suggested, is discussed; however, based on the present results and literature comparisons, we propose an alternative scenario. This scenario hypothesizes that an anthropogenic PCDD precursor input (e.g. pentachlorophenol) results in the contamination. These results and hypothesis imply further investigations are warranted into possible anthropogenic sources in areas where natural PCDD formation has been suggested. PMID:12214647

  16. Constraining recharge and groundwater flow processes in hard-rock aquifers in temperate maritime climate using stable isotope signatures.

    NASA Astrophysics Data System (ADS)

    Pilatova, Katarina; Ofterdinger, Ulrich

    2015-04-01

    Recharge estimates and in understanding flow process in hard rock aquifers pose significant challenges. These arise from structural complexities of the hardrock aquifers and are further complicated by variability of the superficial cover. A comparative study of three metamorphic catchments situated in the North of Ireland is presented in this study, each with contrasting geology, glaciation history and consequently superficial cover. The presented study focusses on two main strains. Firstly, due to lack of existing records, stable water isotopes in precipitation (δ18O and δ2H) were monitored at the research sites and their temporal and spatial variability was examined. Secondly, flow processes and dynamics of groundwater recharge based on continuous records of stable isotopes in groundwater, collected along catchment transects from various depths, and its variability in relation to the acquired precipitation signal were studied. Each precipitation station exhibited distinct isotopic signatures, where weather effect and proximity to coastline are the main controlling factors governing the isotope signatures. Moreover, in each of the stations the isotopic signature varied seasonally and thus stable isotopes proved a useful tool for assessing the dynamics of groundwater recharge. The analysis of isotope signatures in precipitation and groundwater from various depths within the hard rock aquifers allowed to evaluate the timescale of recharge, with rapid responses varying from few days up to several months. In general, the recharge appeared continuous over the hydrological year within wetter catchments with higher annual precipitation amounts purging the hardrock aquifers throughout the year. However, within comparatively dryer catchments recharge has a more seasonal character, predominantly taking place during the winter half of the year. Spatially, the recharge is highly localised within the elevated catchment areas, where superficial deposits are scarce and the

  17. Assisting Groundwater Exploration for Refugee/IDP Camps by Remote Sensing and GIS

    NASA Astrophysics Data System (ADS)

    Wendt, Lorenz; Robl, Jörg; Hilberg, Sylke; Braun, Andreas; Rogenhofer, Edith; Dirnberger, Daniel; Strasser, Thomas; Füreder, Petra; Lang, Stefan

    2015-04-01

    Refugee camps and camps of internally displaced people (IDP) often form spontaneously or have to be established rapidly in remote, rural areas, where little is known about the hydrogeological situation. This requires a rapid assessment of the availability of groundwater to enable humanitarian organisations like Médecins Sans Frontières (MSF) to supply the camp population with sufficient potable water. Within the project EO4HumEn, hydrogeological reconnaissance maps are produced for MSF by integrating remote sensing data like SRTM, Landsat, ASTER, optical very-high resolution (VHR) imagery, and SAR data. Depending on the specific situation of the camps, these maps contain topography, permanent and temporary water bodies, hard rock outcrops and their geological variability, locations of existing boreholes and wells (if available), potential contamination sources, roads and obstacles (e.g. swampland). In areas characterized by unconsolidated sediments, specific landforms like alluvial fans, meanders, levees, deltas or beach ridges are identified. Here, the reconnaissance map can be sufficient to plan drill sites for groundwater abstraction. In hard rock areas, the lithology is determined, if the vegetation cover allows it. Fractures, faults and karst features are mapped to resolve the structural setting. Anomalous vegetation patterns are interpreted in terms of near-surface groundwater. The maps provide an overview of the camp surroundings, and allow the field hydrogeologists to focus their investigations on the most promising locations. The maps are complemented by a literature review on geological maps, articles and reports available for the area of interest. Assisting groundwater exploration by remote sensing data analysis is not a new development, but it has not been widely adopted by the humanitarian community as interfaces between humanitarian organisations and GI-scientists were missing. EO4HumEn fills this gap by a strong interdisciplinary cooperation

  18. Differential Volatile Signatures from Skin, Naevi and Melanoma: A Novel Approach to Detect a Pathological Process

    PubMed Central

    Abaffy, Tatjana; Duncan, Robert; Riemer, Daniel D.; Tietje, Olaf; Elgart, George; Milikowski, Clara; DeFazio, R. Anthony

    2010-01-01

    Background Early detection of melanoma is of great importance to reduce mortality. Discovering new melanoma biomarkers would improve early detection and diagnosis. Here, we present a novel approach to detect volatile compounds from skin. Methods and Findings We used Head Space Solid Phase Micro-Extraction (HS-SPME) and gas chromatography/mass spectrometry (GC/MS) to identify volatile signatures from melanoma, naevi and skin samples. We hypothesized that the metabolic state of tissue alters the profile of volatile compounds. Volatiles released from fresh biopsy tissue of melanoma and benign naevus were compared based on their difference in frequency distribution and their expression level. We also analyzed volatile profiles from frozen tissue, including skin and melanoma. Conclusions Three volatiles, 4-methyl decane, dodecane and undecane were preferentially expressed in both fresh and frozen melanoma, indicating that they are candidate biomarkers. Twelve candidate biomarkers evaluated by fuzzy logic analysis of frozen samples distinguished melanoma from skin with 89% sensitivity and 90% specificity. Our results demonstrate proof-of-principle that there is differential expression of volatiles in melanoma. Our volatile metabolomic approach will lead to a better understanding of melanoma and can enable development of new diagnostic and treatment strategies based on altered metabolism. PMID:21079799

  19. Spatially Resolved Acid Dissolution of IDPs: The State of Carbon and the Abundance of Diamonds in the Dust

    NASA Technical Reports Server (NTRS)

    Brownlee, D. E.; Joswiak, D. J.; Bradley, J. P.; Gezo, J. C.; Hill, H. G. M.

    2000-01-01

    Ultramicrotome sections of IDPs have been successfully etched with HF to isolate and reveal the microdistribution of carbonaceous material. The sections are evaluated for nanodiamonds, 3.4 micron feature, GEMS and the origin of low albedo in small interplanetary particles.

  20. TOP-IDP-Scale: A New Amino Acid Scale Measuring Propensity for Intrinsic Disorder

    PubMed Central

    Campen, Andrew; Williams, Ryan M.; Brown, Celeste J.; Meng, Jingwei; Uversky, Vladimir N.; Dunker, A. Keith

    2009-01-01

    Intrinsically disordered proteins carry out various biological functions while lacking ordered secondary and/or tertiary structure. In order to find general intrinsic properties of amino acid residues that are responsible for the absence of ordered structure in intrinsically disordered proteins we surveyed 517 amino acid scales. Each of these scales was taken as an independent attribute for the subsequent analysis. For a given attribute value X, which is averaged over a consecutive string of amino acids, and for a given data set having both ordered and disordered segments, the conditional probabilities P(so | x) and P(sd | x) for order and disorder, respectively, can be determined for all possible values of X. Plots of the conditional probabilities P(so | x) and P(sd | x) versus X give a pair of curves. The area between these two curves divided by the total area of the graph gives the area ratio value (ARV), which is proportional to the degree of separation of the two probability curves and, therefore, provides a measure of the given attribute’s power to discriminate between order and disorder. As ARV falls between zero and one, larger ARV corresponds to the better discrimination between order and disorder. Starting from the scale with the highest ARV, we applied a simulated annealing procedure to search for alternative scale values and have managed to increase the ARV by more than 10%. The ranking of the amino acids in this new TOP-IDP scale is as follows (from order promoting to disorder promoting): W, F, Y, I, M, L, V, N, C, T, A, G, R, D, H, Q, K, S, E, P. A web-based server has been created to apply the TOP-IDP scale to predict intrinsically disordered proteins (http://www.disprot.org/dev/disindex.php). PMID:18991772

  1. The origin of GEMS in IDPs as deduced from microstructural evolution of amorphous silicates with annealing

    NASA Astrophysics Data System (ADS)

    Davoisne, C.; Djouadi, Z.; Leroux, H.; D'Hendecourt, L.; Jones, A.; Deboffle, D.

    2006-03-01

    Aims.We present laboratory studies of the micro-structural evolution of an amorphous ferro-magnesian silicate, of olivine composition, following thermal annealing under vacuum.Methods.The amorphous silicate was prepared as a thin film on a diamond substrate. Annealing under vacuum was performed at temperatures ranging from 870 to 1020 K. After annealing the thin films were extracted from the substrate and analysed by transmission electron microscopy to infer their microstructural and compositional evolution.Results.Spheroidal metallic nano-particles (2-50 nm) are found within the silicate films, which are still amorphous after annealing at 870 K and partially crystallized into forsterite for annealing up to 1020 K. We interpret this microstructure in terms of a reduction of the initial amorphous silicate FeO component, because of the carbon-rich partial pressure in the furnace due to pumping mechanism. Annealing in a controlled oxygen-rich atmosphere confirms this interpretation. Conclusions.The observed microstructures closely resemble those of the GEMS (Glass with Embedded Metal and Sulphides) found in chondritic IDPs (Interplanetary Dust Particles). Since IDPs contain abundant carbonaceous matter, a solid-state reduction reaction may have occurred during heating in the hot inner regions of the proto-solar disc. Related to this, the presence of forsterite grains grown from the amorphous precursor material clearly demonstrates that condensation from gaseous species is not required to explain the occurrence of forsterite around young protostars and in comets. Forsterite grains in these environments can be formed directly in the solid phase by thermal annealing of amorphous ferro-magnesian silicates precursor under reducing conditions. Finally, locking iron as metallic particles within the silicates explains why astronomical silicates always appear observationally Mg-rich.

  2. Measurement and processing of signatures in the visible range using a calibrated video camera and the CAMDET software package

    NASA Astrophysics Data System (ADS)

    Sheffer, Dan

    1997-06-01

    A procedure for calibration of a color video camera has been developed at EORD. The RGB values of standard samples, together with the spectral radiance values of the samples, are used to calculate a transformation matrix between the RGB and CIEXYZ color spaces. The transformation matrix is then used to calculate the XYZ color coordinates of distant objects imaged in the field. These, in turn, are used in order to calculate the CIELAB color coordinates of the objects. Good agreement between the calculated coordinates and those obtained from spectroradiometric data is achieved. Processing of the RGB values of pixels in the digital image of a scene using the CAMDET software package which was developed at EORD, results in `Painting Maps' in which the true apparent CIELAB color coordinates are used. The paper discusses the calibration procedure, its advantages and shortcomings and suggests a definition for the visible signature of objects. The Camdet software package is described and some examples are given.

  3. Differential ERP Signatures Elicited by Semantic and Syntactic Processing in Scenes

    PubMed Central

    Võ, Melissa L.-H.; Wolfe, Jeremy M.

    2016-01-01

    In sentence processing, semantic and syntactic violations elicit differential brain responses in ERP recordings: An N400 signals semantic violations, while a P600 marks inconsistent syntactic structure. Does the brain register similar distinctions in scene perception? Participants viewed “semantic inconsistencies” created by presenting objects that were incongruent with a scene's meaning and “syntactic inconsistencies” in which an object violated structural rules. We found a clear dissociation between semantic and syntactic processing: Semantic inconsistencies produced negative deflections in the N300/N400 time window, while syntactic inconsistencies elicited a late positivity resembling the P600 found for syntax manipulations in sentence processing. Interestingly, extreme syntax violations such as a floating toast, showed an initial increase in attentional deployment, but failed to produce a P600 effect. We therefore conclude that different neural populations are active during semantic and syntactic processing in scenes and that impossible object placements may be processed categorically different from syntactically inconsistent placements. PMID:23842954

  4. Neural signatures of conscious and unconscious emotional face processing in human infants.

    PubMed

    Jessen, Sarah; Grossmann, Tobias

    2015-03-01

    Human adults can process emotional information both with and without conscious awareness, and it has been suggested that the two processes rely on partly distinct brain mechanisms. However, the developmental origins of these brain processes are unknown. In the present event-related brain potential (ERP) study, we examined the brain responses of 7-month-old infants in response to subliminally (50 and 100 msec) and supraliminally (500 msec) presented happy and fearful facial expressions. Our results revealed that infants' brain responses (Pb and Nc) over central electrodes distinguished between emotions irrespective of stimulus duration, whereas the discrimination between emotions at occipital electrodes (N290 and P400) only occurred when faces were presented supraliminally (above threshold). This suggests that early in development the human brain not only discriminates between happy and fearful facial expressions irrespective of conscious perception, but also that, similar to adults, supraliminal and subliminal emotion processing relies on distinct neural processes. Our data further suggest that the processing of emotional facial expressions differs across infants depending on their behaviorally shown perceptual sensitivity. The current ERP findings suggest that distinct brain processes underpinning conscious and unconscious emotion perception emerge early in ontogeny and can therefore be seen as a key feature of human social functioning. PMID:25528130

  5. Modern Microbial Fossilization Processes as Signatures for Interpreting Ancient Terrestrial and Extraterrestrial Microbial Forms

    NASA Technical Reports Server (NTRS)

    Morris, Penny A.; Wentworth, Susan J.; Nelman, Mayra; Byrne, Monica; Longazo, Teresa; Galindo, Charles; McKay, David S.; Sams, Clarence

    2003-01-01

    Terrestrial biotas from microbially dominated hypersaline environments will help us understand microbial fossilization processes. Hypersaline tolerant biota from Storr's Lake, San Salvador Island (Bahamas), Mono Lake (California), and the Dead Sea (Israel) represent marine and nonmarine sites for comparative studies of potential analogs for interpreting some Mars meteorites and Mars sample return rocks [1,2,3,4,5,6]. The purpose of this study is to compare microbial fossilization processes, the dominant associated minerals, and potential diagenic implications.

  6. Signature control

    NASA Astrophysics Data System (ADS)

    Pyati, Vittal P.

    The reduction of vehicle radar signature is accomplished by means of vehicle shaping, the use of microwave frequencies-absorbent materials, and either passive or active cancellation techniques; such techniques are also useful in the reduction of propulsion system-associated IR emissions. In some anticipated scenarios, the objective is not signature-reduction but signature control, for deception, via decoy vehicles that mimic the signature characteristics of actual weapons systems. As the stealthiness of airframes and missiles increases, their propulsion systems' exhaust plumes assume a more important role in detection by an adversary.

  7. Chemical Heterogeneity of a Large Cluster IDP: Clues to its Formation History Using X-ray Fluorescence Mapping and XANES Spectroscopy

    NASA Technical Reports Server (NTRS)

    Wirick, S.; Flynn, G. J.; Sutton, S.; Zolensky, M. E.

    2013-01-01

    Chondritic porous IDPs may be among the most primitive objects found in our solar system [1]. They consist of many micron to submicron minerals, glasses and carbonaceous matter [2,3,4,5,6,7] with > 10(exp 4) grains in a 10 micron cluster [8]. Speculation on the environment where these fine grained, porous IDPs formed varies with possible sources being presolar dusty plasma clouds, protostellar condensation, solar asteroids or comets [4,6,9]. Also, fine grained dust forms in our solar system today [10,11]. Isotopic anomalies in some particles in IDPs suggest an interstellar source[4,7,12]. IDPs contain relic particles left from the dusty plasma that existed before the protostellar disk formed and other grains in the IDPs formed later after the cold dense nebula cloud collapsed to form our protostar and other grains formed more recently. Fe and CR XANES spectroscopy is used here to investigate the oxygen environment in a large (>50 10 micron or larger sub-units) IDP. Conclusions: Analyzing large (>50 10 micron or larger sub-units) CP IDPs gives one a view on the environments where these fine dust grains formed which is different from that found by only analyzing the small, 10 micron IDPs. As with cluster IDP L2008#5 [3], L2009R2 cluster #13 appears to be an aggregate of grains that sample a diversity of solar and perhaps presolar environments. Sub-micron, grain by grain measurement of trace element contents and elemental oxidation states determined by XANES spectroscopy offers the possibility of understanding the environments in which these grains formed when compared to standard spectra. By comparing thermodynamic modeling of condensates with analytical data an understanding of transport mechanisms operating in the early solar system may be attained.

  8. Stable isotope signatures in bulk samples from two soils with contrasting characteristics. What do they tell about ongoing pedogenic processes?

    NASA Astrophysics Data System (ADS)

    Jiménez-Morillo, Nicasio T.; dos Anjos Leal, Otávio; Knicker, Heike; Pinheiro Dick, Deborah; González-Vila, Francisco J.; González-Pérez, José A.

    2014-05-01

    Isotopic ratio mass spectrometry (IRMS) has been proven as a promising tool for the monitoring of biogeochemical processes in soil. In this work, stable isotope signatures of light elements δ15N, δ13C, δ18O and δD were determined for two soils with contrasting characteristics in terms of climate, vegetation, land use and management. The studied soils were a Cambisol from a subtropical area (Paraná region, South Brazil) and an Arenosol from a Mediterranean climate (Andalusia, South Spain). A Flash 2000 HT (N, C, S, H and O) elemental analyzer (Thermo Scientific) coupled to a Delta V Advantage IRMS (Thermo Scientific) was used. Isotopic ratios are reported as parts per thousand (o ) deviations from appropriate standards recognized by the international atomic energy agency (IAEA). In a first approach we took advantage of the well-known different δ13C signature between plants using either the C4 or C3 carbon fixation pathway (O'Leary, 1981). The Arenosol (Spain) revealed a δ13C signature which is clearly in the range of C3 plants (-26 to -30 o ). Different plant canopies (tree, shrubs or ferns) caused only slight variations δ13C (STD= 0.98). In contrast, the Cambisol (Brazil) showed less depletion of the heavier carbon isotope corresponding to C4 predominant vegetation. In addition an increase from -19 o in the soil surface (0 - 5 cm) to -16 o in the subsoil (20 - 30 cm) was observed in line with a recent (2 years old) shift of the land use from the predominant C4 grassland to eucalypt (C3) cultivation. Crossplots of δ15N vs. δ18O may provide information about nitrate (NO3-) sources and N cycling (Kendall, 1998). In the Mediterranean Arenosol this signal (δ18O = 30o δ15N = 2o ) was found compatible with a predominant nitrate atmospheric deposition, whereas the signal in the Brazilian Cambisol pointed to the use of a mineral N fertilization with signs of denitrification processes (δ18O = 13o δ15N = 9o ). No conclusive results could be obtained from the

  9. The Neural Signatures of Processing Semantic End Values in Automatic Number Comparisons

    PubMed Central

    Pinhas, Michal; Buchman, Chananel; Lavro, Dmitri; Mesika, David; Tzelgov, Joseph; Berger, Andrea

    2015-01-01

    The brain activity associated with processing numerical end values has received limited research attention. The present study explored the neural correlates associated with processing semantic end values under conditions of automatic number processing. Event-related potentials (ERPs) were recorded while participants performed the numerical Stroop task, in which they were asked to compare the physical size of pairs of numbers, while ignoring their numerical values. The smallest end value in the set, which is a task irrelevant factor, was manipulated between participant groups. We focused on the processing of the lower end values of 0 and 1 because these numbers were found to be automatically tagged as the “smallest.” Behavioral results showed that the size congruity effect was modulated by the presence of the smallest end value in the pair. ERP data revealed a spatially extended centro-parieto-occipital P3 that was enhanced for congruent versus incongruent trials. Importantly, over centro-parietal sites, the P3 congruity effect (congruent minus incongruent) was larger for pairs containing the smallest end value than for pairs containing non-smallest values. These differences in the congruency effect were localized to the precuneus. The presence of an end value within the pair also modulated P3 latency. Our results provide the first neural evidence for the encoding of numerical end values. They further demonstrate that the use of end values as anchors is a primary aspect of processing symbolic numerical information. PMID:26640436

  10. Attachment Patterns Trigger Differential Neural Signature of Emotional Processing in Adolescents

    PubMed Central

    Decety, Jean; Huepe, David; Cardona, Juan Felipe; Canales-Johnson, Andres; Sigman, Mariano; Mikulan, Ezequiel; Helgiu, Elena; Baez, Sandra; Manes, Facundo; Lopez, Vladimir; Ibañez, Agustín

    2013-01-01

    Background Research suggests that individuals with different attachment patterns process social information differently, especially in terms of facial emotion recognition. However, few studies have explored social information processes in adolescents. This study examined the behavioral and ERP correlates of emotional processing in adolescents with different attachment orientations (insecure attachment group and secure attachment group; IAG and SAG, respectively). This study also explored the association of these correlates to individual neuropsychological profiles. Methodology/Principal Findings We used a modified version of the dual valence task (DVT), in which participants classify stimuli (faces and words) according to emotional valence (positive or negative). Results showed that the IAG performed significantly worse than SAG on tests of executive function (EF attention, processing speed, visuospatial abilities and cognitive flexibility). In the behavioral DVT, the IAG presented lower performance and accuracy. The IAG also exhibited slower RTs for stimuli with negative valence. Compared to the SAG, the IAG showed a negative bias for faces; a larger P1 and attenuated N170 component over the right hemisphere was observed. A negative bias was also observed in the IAG for word stimuli, which was demonstrated by comparing the N170 amplitude of the IAG with the valence of the SAG. Finally, the amplitude of the N170 elicited by the facial stimuli correlated with EF in both groups (and negative valence with EF in the IAG). Conclusions/Significance Our results suggest that individuals with different attachment patterns process key emotional information and corresponding EF differently. This is evidenced by an early modulation of ERP components’ amplitudes, which are correlated with behavioral and neuropsychological effects. In brief, attachments patterns appear to impact multiple domains, such as emotional processing and EFs. PMID:23940552

  11. DETERMINING CARBON ISOTOPE SIGNATURES FROM MICROMETEOROLOGICAL MEASUREMENTS: IMPLICATIONS FOR STUDYING BIOSPHERE-ATMOSPHERE EXCHANGE PROCESSES

    Technology Transfer Automated Retrieval System (TEKTRAN)

    In recent years considerable effort has been focused on combining micrometeorological and stable isotope techniques to elucidate and study biosphere-atmosphere exchange processes. At the ecosystem scale, these methods are increasingly being used to address a number of challenging problems, including...

  12. New class of supersymmetric signatures in the processes gg{yields}HH', VH

    SciTech Connect

    Gounaris, G. J.; Layssac, J.; Renard, F. M.

    2009-07-01

    Within the minimal supersymmetric model (MSSM) and standard model (SM) frameworks, we analyze the 1loop electroweak predictions for the helicity amplitudes describing the 17 processes gg{yields}HH', and the 9 processes gg{yields}VH; where H, H{sup '} denote Higgs or Goldstone bosons, while V=Z, W{sup {+-}}. Concentrating on MSSM, we then investigate how the asymptotic helicity conservation (HCns) property of supersymmetry (SUSY) affects the amplitudes at the LHC energy range and what is the corresponding situation in the SM, where no HCns theorem exists. HCns is subsequently used to construct many relations among the cross sections of the above MSSM processes, depending only on the standard MSSM angles {alpha} and {beta} characterizing the two Higgs doublets. These relations should be asymptotically exact but as the energy decreases toward the LHC range, mass-depending deviations should start appearing. Provided the SUSY scale is not too high, these relations may remain roughly correct, even at the LHC energy range.

  13. Chicxulub Impact Melts: Geochemical Signatures of Target Lithology Mixing and Post-Impact Hydrothermal Fluid Processes

    NASA Technical Reports Server (NTRS)

    Kring, David A.; Zurcher, Lukas; Horz, Freidrich; Mertzmann, Stanley A.

    2004-01-01

    Impact melts within complex impact craters are generally homogeneous, unless they differentiated, contain immiscible melt components, or were hydrothermally altered while cooling. The details of these processes, however, and their chemical consequences, are poorly understood. The best opportunity to unravel them may lie with the Chicxulub impact structure, because it is the world s most pristine (albeit buried) large impact crater. The Chicxulub Scientific Drilling Project recovered approx. 100 meters of impactites in a continuous core from the Yaxcopoil-1 (YAX-1) borehole. This dramatically increased the amount of melt available for analyses, which was previously limited to two small samples N17 and N19) recovered from the Yucatan-6 (Y-6) borehole and one sample (N10) recovered from the Chicxulub-1 (C-1) borehole. In this study, we describe the chemical compositions of six melt samples over an approx. 40 m section of the core and compare them to previous melt samples from the Y-6 and C-1 boreholes.

  14. Noble Gas Signatures in Antrim Shale Gas in the Michigan Basin - Assessing Compositional Variability and Transport Processes

    NASA Astrophysics Data System (ADS)

    Wen, T.; Castro, M. C.; Ellis, B. R.; Hall, C. M.; Lohmann, K. C.; Bouvier, L.

    2014-12-01

    Recent studies in the Michigan Basin looked at the atmospheric and terrigenic noble gas signatures of deep brines to place constraints on the past thermal history of the basin and to assess the extent of vertical transport processes within this sedimentary system. In this contribution, we present noble gas data of shale gas samples from the Antrim shale formation in the Michigan Basin. The Antrim shale was one of the first economic shale-gas plays in the U.S. and has been actively developed since the 1980's. This study pioneers the use of noble gases in subsurface shale gas in the Michigan Basin to clarify the nature of vertical transport processes within the sedimentary sequence and to assess potential variability of noble gas signatures in shales. Antrim Shale gas samples were analyzed for all stable noble gases (He, Ne, Ar, Kr, Xe) from samples collected at depths between 300 and 500m. Preliminary results show R/Ra values (where R and Ra are the measured and atmospheric 3He/4He ratios, respectively) varying from 0.022 to 0.21. Although most samples fall within typical crustal R/Ra range values (~0.02-0.05), a few samples point to the presence of a mantle He component with higher R/Ra ratios. Samples with higher R/Ra values also display higher 20Ne/22Ne ratios, up to 10.4, and further point to the presence of mantle 20Ne. The presence of crustally produced nucleogenic 21Ne and radiogenic 40Ar is also apparent with 21Ne/22Ne ratios up to 0.033 and 40Ar/36Ar ratios up to 312. The presence of crustally produced 4He, 21Ne and 40Ar is not spatially homogeneous within the Antrim shale. Areas of higher crustal 4He production appear distinct to those of crustally produced 21Ne and 40Ar and are possibly related the presence of different production levels within the shale with varying concentrations of parent elements.

  15. Drought tolerance as a driver of tropical forest assembly: resolving spatial signatures for multiple processes.

    PubMed

    Bartlett, M K; Zhang, Y; Yang, J; Kreidler, N; Sun, S w; Lin, L; Hu, Y H; Cao, K F; Sack, L

    2016-02-01

    Spatial patterns in trait variation reflect underlying community assembly processes, allowing us to test hypotheses about their trait and environmental drivers by identifying the strongest correlates of characteristic spatial patterns. For 43 evergreen tree species (> 1 cm dbh) in a 20-ha seasonal tropical rainforest plot in Xishuangbanna, China, we compared the ability of drought-tolerance traits, other physiological traits, and commonly measured functional traits to predict the spatial patterns expected from the assembly processes of habitat associations, niche-overlap-based competition, and hierarchical competition. We distinguished the neighborhood-scale (0-20 m) patterns expected from competition from larger-scale habitat associations with a wavelet method. Species' drought tolerance and habitat variables related to soil water supply were strong drivers of habitat associations, and drought tolerance showed a significant spatial signal for influencing competition. Overall, the traits most strongly associated with habitat, as quantified using multivariate models, were leaf density, leaf turgor loss point (π(tlp); also known as the leaf wilting point), and stem hydraulic conductivity (r2 range for the best fit models = 0.27-0.36). At neighborhood scales, species spatial associations were positively correlated with similarity in π(tlp), consistent with predictions for hierarchical competition. Although the correlation between π(tlp) and interspecific spatial associations was weak (r2 < 0.01), this showed a persistent influence of drought tolerance on neighborhood interactions and community assembly. Quantifying the full impact of traits on competitive interactions in forests may require incorporating plasticity among individuals within species, especially among specific life stages, and moving beyond individual traits to integrate the impact of multiple traits on whole-plant performance and resource demand. PMID:27145624

  16. Inplementation of an automated signal processing approach for the analysis of chemical spectral signatures collected from FT-IR mounted in an aircraft

    SciTech Connect

    Kroutil, Robert T

    2008-01-01

    The automated detection of chemical spectral signatures using a passive infrared Fourier Transform Infrared (FT-IR) Spectrometer mounted in an aircraft is a difficult challenge due to the small total infrared energy contribution of a particular chemical species compared to the background signature. The detection of spectral signatures is complicated by the fact that a large, widely varying infrared background is present that is coupled with the presence of a number of chemical interferents in the atmosphere. This paper describes a mathematical technique that has been demonstrated to automatically detect specific chemical species in an automated processing environment. The data analysis methodology has been demonstrated to be effective using data of low spectral resolution at low aircraft altitudes. An overview of the implementation and basic concepts of the approach are presented.

  17. The Global Geometry of River Drainage Basins and the Signature of Tectonic and Autogenic Processes

    NASA Astrophysics Data System (ADS)

    Giachetta, E.; Willett, S.

    2015-12-01

    The plan-form structure of the world's river basins contains extensive information regarding tectonic, paleo-geographic and paleo-climate conditions, but interpretation of this structure is complicated by the need to disentangle these processes from the autogenic behavior of fluvial processes. One method of interpreting this structure is by utilizing the well-established scaling between drainage area and channel slope. Integration of this scaling relationship predicts a relationship between channel length and downstream integrated drainage area, referred to in recent studies as χ (Willett et al., 2014). In this paper, we apply this methodology at a continental scale by calculating χ for the world's river networks using hydrological information from the HydroSHED (Hydrological data and maps based on SHuttleElevation Derivatives at multiple Scales) suite of geo-referenced data sets (drainage directions and flow accumulations). River pixels were identified using a minimum drainage area of 5 km2. A constant value of m/n of 0.45 was assumed. We applied a new method to correct χ within closed basins where base level is different from sea level. Mapping of χ illustrates the geometric stability of a river network, thus highlighting where tectonic or climatic forcing has perturbed the shape and geometry. Each continent shows characteristic features. Continental rift margins on all continents show clear asymmetric escarpments indicating inland migration. Active orogenic belts break up older river basins, but are difficult to interpret because of spatially variable uplift rates. Regions of recent tilting are evident even in cratonic areas by lateral reorganizations of basins. Past and pending river captures are identified on all continents. Very few regions on Earth appear to be in near-equilibrium, though some are identified; for example the Urals appears to provide a stable continental divide for Eurasia. Our analysis of maps of χ at the global scale quantifies a

  18. Effects of surficial modification processes on thermal infrared signatures in the arid southwestern United States

    NASA Technical Reports Server (NTRS)

    Weitz, Catherine M.; Farr, Tom G.

    1992-01-01

    Thermal infrared spectra from both laboratory and remote sensing instruments were used to distinguish different age lava flows with varying amounts of surficial modification at Cima and Lunar Crater volcanic fields. The modification processes affecting the lava flows cause spectral differences that can be seen in remotely sensed emittance spectra from the thermal infrared multispectral scanner. Important influences on the thermal infrared spectra include aeolian mantling, vegetation, lave flow roughness, and rock varnish. Laboratory thermal infrared reflectance spectra of the subaerially exposed surfaces of 1-15 cm basalt fragments at Cima volcanic field show a feature attributable to rock varnish on the younger flows (0.14-0.75 m.y.) that is lacking on the older flows (greater than 0.8 m.y.). This suggests that rock varnish is thinner on the older flows at Cima volcanic field. Scanning electron microscope images and thin sections of the different age flows at Cima volcanic field support the conclusion that rock varnish is thinner and may be eroding on the older flow surfaces.

  19. Process signatures in regional patterns of shoreline change on annual to decadal time scales

    NASA Astrophysics Data System (ADS)

    Lazarus, Eli D.; Murray, A. Brad

    2007-10-01

    Gradients in wave-driven alongshore sediment transport influence the morphologies of sediment-covered coastlines on a range of spatial and temporal scales, affecting accretion and erosion patterns relevant to human development. Recent theoretical findings predict that a correlation between shoreline change and shoreline curvature results from patterns of alongshore sediment flux; the sign (positive or negative) of that correlation depends on whether high- or low-angle waves dominated the wave climate. Using lidar surveys of the northern North Carolina coast from 1996-2005 to document shoreline change and quantify alongshore patterns of erosion and deposition, we isolate these signals diagnostic of alongshore-transport processes. Our analyses show a persistent, significant negative correlation between shoreline-position change and shoreline curvature consistent with a low-angle-dominated incident wave climate over the last decade. At large spatial scales, convex-seaward promontories have eroded landward, while concave-seaward bays have aggraded seaward, resulting in an apparent diffusion of alongshore morphological features.

  20. Relative Amino Acid Concentrations as a Signature for Parent Body Processes of Carbonaceous Chondrites

    NASA Technical Reports Server (NTRS)

    Botta, Oliver; Glavin, Daniel P.; Kminek, Gerhard; Bada, Jeffrey L.

    2002-01-01

    Most meteorites are thought to have originated from objects in the asteroid belt. Carbonaceous chondrites, which contain significant amounts of organic carbon including complex organic compounds, have also been suggested to be derived from comets. The current model for the synthesis of organic compounds found in carbonaceous chondrites includes the survival of interstellar organic compounds and the processing of some of these compounds on the meteoritic parent body. The amino acid composition of five CM carbonaceous chondrites, two CIs, one CR, and one CV3 have been measured using hot water extraction-vapor hydrolysis, OPA/NAC derivatization and high-performance liquid chromatography (HPLC). Total amino acid abundances in the bulk meteorites as well as the amino acid concentrations relative to glycine = 1.0 for beta-alanine, alpha-aminoisobutyric acid and D-alanine were determined. Additional data for three Antarctic CM meteorites were obtained from the literature. All CM meteorites analyzed in this study show a complex distribution of amino acids and a high variability in total concentration ranging from approx. 15,300 to approx. 5800 parts per billion (ppb), while the CIs show a total amino acid abundance of approx. 4300 ppb. The relatively (compared to glycine) high AIB content found in all the CMs is a strong indicator that Strecker-cyanohydrin synthesis is the dominant pathway for the formation of amino acids found in these meteorites. The data from the Antarctic CM carbonaceous chondrites are inconsistent with the results from the other CMs, perhaps due to influences from the Antarctic ice that were effective during their residence time. In contrast to CMs, the data from the CI carbonaceous chondrites indicate that the Strecker synthesis was not active on their parent bodies.

  1. Annotator: Post-processing Software for generating function-based signatures from quantitative mass spectrometry

    PubMed Central

    Sylvester, Juliesta E.; Bray, Tyler S.; Kron, Stephen J.

    2012-01-01

    Mass spectrometry is used to investigate global changes in protein abundance in cell lysates. Increasingly powerful methods of data collection have emerged over the past decade, but this has left researchers with the task of sifting through mountains of data for biologically significant results. Often, the end result is a list of proteins with no obvious quantitative relationships to define the larger context of changes in cell behavior. Researchers are often forced to perform a manual analysis from this list or to fall back on a range of disparate tools, which can hinder the communication of results and their reproducibility. To address these methodological problems we developed Annotator, an application that filters validated mass spectrometry data and applies a battery of standardized heuristic and statistical tests to determine significance. To address systems-level interpretations we incorporated UniProt and Gene Ontology keywords as statistical units of analysis, yielding quantitative information about changes in abundance for an entire functional category. This provides a consistent and quantitative method for formulating conclusions about cellular behavior, independent of network models or standard enrichment analyses. Annotator allows for “bottom-up” annotations that are based on experimental data and not inferred by comparison to external or hypothetical models. Annotator was developed as an independent post-processing platform that runs on all common operating systems, thereby providing a useful tool for establishing the inherently dynamic nature of functional annotations, which depend on results from on-going proteomic experiments. Annotator is available for download at http://people.cs.uchicago.edu/~tyler/annotator/annotator_desktop_0.1.tar.gz. PMID:22224429

  2. Stable Isotopic Signatures in the Isolated Brine Cyroecosystem of Lake Vida Reveal Evidence of both Abiotic and Biotic Processes

    NASA Astrophysics Data System (ADS)

    Murray, A. E.; Ostrom, N. E.; Glazer, B. T.; McKay, C.; Kenig, F.; Loeffler, F. E.; Fritsen, C. H.; Doran, P. T.

    2011-12-01

    Lake Vida in the Victoria Valley of East Antarctica harbors ice-entrained brine that has been isolated from surface processes for several thousand years. The brine conditions (permanently dark, temperature of -13.4 °C, lack of oxygen, and pH of 6.2) and geochemistry are highly unusual. As an example, the brine contains excessive quantities of both reduced and oxidized nitrogen in nearly all forms, which in several cases are the highest levels found among natural ecosystems on Earth. Though this cryoecosystem appears to be relatively inhospitable, we have evidence that microbial life persists in abundance (cell levels over 107 cells per mL), is capable of protein production at in situ temperatures, and harbors a unique, but not necessarily novel, assemblage of bacterial phylotypes spanning at least eight phyla. In order to assess in situ microbial activities occurring today and in the past, and test hypotheses concerning energy generation in the brine cryoecosystem, the stable isotope signatures of nitrogen, oxygen, and hydrogen have been characterized in liquid and dissolved gas phases of the brine. The data provide evidence for both biotic and potentially abiotic formation of different fractions. The site preference of 15N-nitrous oxide (-3.64) suggests that the primary source of this dissolved gas, which is found at levels as high as 86 μM, is biologically produced by denitrification pathways. This appears to be consistent with detection of Marinobacter and Psychrobacter-related bacterial rRNA gene sequences and isolates in the brine microbial community. On the other hand, dissolved hydrogen present in the brine harbors an δH-H2 isotope signature suggesting that abiotic (potentially via serpentinization) or biotic production is equivocal based on the significant levels of fractionation observed. We postulate however, that a serpentinization production route is more favorable in this system that lies in a basin comprised of Ferrar dolerite sills and granite

  3. Model parameters conditioning on regional hydrologic signatures for process-based design flood estimation in ungauged basins.

    NASA Astrophysics Data System (ADS)

    Biondi, Daniela; De Luca, Davide Luciano

    2015-04-01

    The use of rainfall-runoff models represents an alternative to statistical approaches (such as at-site or regional flood frequency analysis) for design flood estimation, and constitutes an answer to the increasing need for synthetic design hydrographs (SDHs) associated to a specific return period. However, the lack of streamflow observations and the consequent high uncertainty associated with parameter estimation, usually pose serious limitations to the use of process-based approaches in ungauged catchments, which in contrast represent the majority in practical applications. This work presents the application of a Bayesian procedure that, for a predefined rainfall-runoff model, allows for the assessment of posterior parameters distribution, using the limited and uncertain information available for the response of an ungauged catchment (Bulygina et al. 2009; 2011). The use of regional estimates of river flow statistics, interpreted as hydrological signatures that measure theoretically relevant system process behaviours (Gupta et al. 2008), within this framework represents a valuable option and has shown significant developments in recent literature to constrain the plausible model response and to reduce the uncertainty in ungauged basins. In this study we rely on the first three L-moments of annual streamflow maxima, for which regressions are available from previous studies (Biondi et al. 2012; Laio et al. 2011). The methodology was carried out for a catchment located in southern Italy, and used within a Monte Carlo scheme (MCs) considering both event-based and continuous simulation approaches for design flood estimation. The applied procedure offers promising perspectives to perform model calibration and uncertainty analysis in ungauged basins; moreover, in the context of design flood estimation, process-based methods coupled with MCs approach have the advantage of providing simulated floods uncertainty analysis that represents an asset in risk-based decision

  4. Signatures of Förster and Dexter transfer processes in coupled nanostructures for linear and two-dimensional coherent optical spectroscopy

    NASA Astrophysics Data System (ADS)

    Specht, Judith F.; Richter, Marten

    2015-03-01

    In this manuscript, we study the impact of the two Coulomb induced resonance energy transfer processes, Förster and Dexter coupling, on the spectral signatures obtained by double quantum coherence spectroscopy. We show that the specific coupling characteristics allow us to identify the underlying excitation transfer mechanism by means of specific signatures in coherent spectroscopy. Therefore, we control the microscopic calculated coupling strength of spin preserving and spin flipping Förster transfer processes by varying the mutual orientation of the two quantum emitters. The calculated spectra reveal the optical selection rules altered by Förster and Dexter coupling between two semiconductor quantum dots. We show that Dexter coupling between bright and dark two-exciton states occurs.

  5. Search for the Higgs Boson and Rare Standard Model Processes in the ET+B-Jets Signature at the Collider Detector at Fermilab

    SciTech Connect

    Potamianos, Karolos Jozef

    2011-12-01

    We study rare processes of the standard model of particle physics (SM) in events with missing transverse energy ET, no leptons, and two or three jets, of which at least one is identified as originating from a $b$-quark (ET+b-jets signature). We present a search for the SM Higgs boson produced in association with a $W$ or $Z$ boson when the Higgs decays into \\bbbar. We consider the scenario where $Z \\to \

  6. A comprehensive data processing plan for crop calendar MSS signature development from satellite imagery: Crop identification using vegetation phenology

    NASA Technical Reports Server (NTRS)

    Hlavka, C. A. (Principal Investigator); Carlyle, S. M.; Haralick, R. M.; Yokoyama, R.

    1978-01-01

    The author has identified the following significant results. The phenological method of crop identification involves the creation of crop signatures which characterize multispectral observations as phenological growth states. The phenological signature models spectral reflectance explicitly as a function of crop maturity rather than as a function of date. A correspondence of time to growth state is established which minimizes the smallest difference between the given multispectral multitemporal vector and a category mean vector. The application of the method to the identification of winter wheat and corn shows (1) the method is capable of discriminating crop type with about the same degree of accuracy as more traditional classifiers; (2) the use of LANDSAT observations on two or more dates yields better results than the use of a single observation; and (3) some potential is demonstrated for labeling the degree of maturity of the crop, as well as the crop type.

  7. Improving the automated detection of refugee/IDP dwellings using the multispectral bands of the WorldView-2 satellite

    NASA Astrophysics Data System (ADS)

    Kemper, Thomas; Gueguen, Lionel; Soille, Pierre

    2012-06-01

    The enumeration of the population remains a critical task in the management of refugee/IDP camps. Analysis of very high spatial resolution satellite data proofed to be an efficient and secure approach for the estimation of dwellings and the monitoring of the camp over time. In this paper we propose a new methodology for the automated extraction of features based on differential morphological decomposition segmentation for feature extraction and interactive training sample selection from the max-tree and min-tree structures. This feature extraction methodology is tested on a WorldView-2 scene of an IDP camp in Darfur Sudan. Special emphasis is given to the additional available bands of the WorldView-2 sensor. The results obtained show that the interactive image information tool is performing very well by tuning the feature extraction to the local conditions. The analysis of different spectral subsets shows that it is possible to obtain good results already with an RGB combination, but by increasing the number of spectral bands the detection of dwellings becomes more accurate. Best results were obtained using all eight bands of WorldView-2 satellite.

  8. Loss of solar He and Ne from IDPS in subducting sediment: Diffusion and the effect of phase changes

    NASA Technical Reports Server (NTRS)

    Hiyagon, H.

    1994-01-01

    The results of the diffusion experiment for solar He and Ne in IDP's in a magnetic separate from Pacific Ocean sediment suggest that solar He and Ne would be easily released from IDP grains and hence lost from subducting slabs at shallow depths. However, since the diffusion experiments was conducted under high vacuum, there may be a possibility that magnetite grains, which are supposedly the main constituent of the magnetic fraction, might be partly reduced to form a metal phase due to low oxygen fugacity in the experimental condition. If this is the case, such a phase change might affect the gas release and hence the results of the diffusion coefficients. In order to examine whether or not such a phase change really occurred in the condition of the diffusion experiment, I conducted a heating experiment for a magnetic separate from Pacific Ocean sediment. In the same condition as in the diffusion experiment, and the run products were examined with an x ray diffraction method. Three samples were prepared: they were wrapped with platinum foil, put in a vacuum line, and heated in a molybdenum crucible for two hours at 500 C, 800 C,and 950 C, respectively. After cooling the furnace, the samples were taken out from the crucible and analyzed with an x ray diffraction method.

  9. Shining new light on the brain’s “Bilingual Signature:” A functional Near Infrared Spectroscopy investigation of semantic processing

    PubMed Central

    Kovelman, Ioulia; Shalinsky, Mark H.; Berens, Melody S.; Petitto, Laura-Ann

    2008-01-01

    Decades of research have shown that, from an early age, proficient bilinguals can speak each of their two languages separately (similar to monolinguals) or rapidly switch between them (dissimilar to monolinguals). Thus we ask do monolingual and bilingual brains process language similarly or dissimilarly, and is this affected by the language context? Using an innovative brain imaging technology, functional Near Infrared Spectroscopy (fNIRS), we investigated how adult bilinguals process semantic information, both in speech and in print, in a monolingual language context (one language at a time) or in a bilingual language context (two languages in rapid alternation). While undergoing fNIRS recording, ten early-exposed, highly-proficient Spanish-English bilinguals completed a Semantic Judgment task in monolingual and bilingual contexts, and were compared to ten English monolingual controls. Two hypotheses were tested: the Signature Hypothesis predicts that early, highly proficient bilinguals will recruit neural tissue to process language differently from monolinguals across all language contexts. The Switching Hypothesis predicts that bilinguals will recruit neural tissue to process language similarly to monolinguals, when using one language at a time. Supporting the Signature Hypothesis, in the monolingual context, bilinguals and monolinguals showed differences in both hemispheres in the recruitment of DLPFC (BA 46/9) and IFC (BA 47/11), but similar recruitment of Broca’s area (BA 44/45). In particular, in the monolingual context, bilinguals showed greater signal intensity in channels maximally overlaying DLPFC and IFC regions as compared to monolinguals. In the bilingual context, bilinguals demonstrated a more robust recruitment of right DLPFC and right IFC. These findings reveal how extensive early bilingual exposure modifies language organization in the brain—thus imparting a possible “bilingual signature.” They further shed fascinating new light on how the

  10. IDP camp evolvement analysis in Darfur using VHSR optical satellite image time series and scientific visualization on virtual globes

    NASA Astrophysics Data System (ADS)

    Tiede, Dirk; Lang, Stefan

    2010-11-01

    In this paper we focus on the application of transferable, object-based image analysis algorithms for dwelling extraction in a camp for internally displaced people (IDP) in Darfur, Sudan along with innovative means for scientific visualisation of the results. Three very high spatial resolution satellite images (QuickBird: 2002, 2004, 2008) were used for: (1) extracting different types of dwellings and (2) calculating and visualizing added-value products such as dwelling density and camp structure. The results were visualized on virtual globes (Google Earth and ArcGIS Explorer) revealing the analysis results (analytical 3D views,) transformed into the third dimension (z-value). Data formats depend on virtual globe software including KML/KMZ (keyhole mark-up language) and ESRI 3D shapefiles streamed as ArcGIS Server-based globe service. In addition, means for improving overall performance of automated dwelling structures using grid computing techniques are discussed using examples from a similar study.

  11. IDP camp evolvement analysis in Darfur using VHSR optical satellite image time series and scientific visualization on virtual globes

    NASA Astrophysics Data System (ADS)

    Tiede, Dirk; Lang, Stefan

    2009-09-01

    In this paper we focus on the application of transferable, object-based image analysis algorithms for dwelling extraction in a camp for internally displaced people (IDP) in Darfur, Sudan along with innovative means for scientific visualisation of the results. Three very high spatial resolution satellite images (QuickBird: 2002, 2004, 2008) were used for: (1) extracting different types of dwellings and (2) calculating and visualizing added-value products such as dwelling density and camp structure. The results were visualized on virtual globes (Google Earth and ArcGIS Explorer) revealing the analysis results (analytical 3D views,) transformed into the third dimension (z-value). Data formats depend on virtual globe software including KML/KMZ (keyhole mark-up language) and ESRI 3D shapefiles streamed as ArcGIS Server-based globe service. In addition, means for improving overall performance of automated dwelling structures using grid computing techniques are discussed using examples from a similar study.

  12. Long range recognition and selection in IDPs: the interactions of the C-terminus of p53

    PubMed Central

    Kannan, Srinivasaraghavan; Lane, David P.; Verma, Chandra S.

    2016-01-01

    The C-terminal domain of p53 is an extensively studied IDP, interacting with different partners through multiple distinct conformations. To explore the interplay between preformed structural elements and intrinsic fluctuations in its folding and binding we combine extensive atomistic equilibrium and non-equilibrium simulations. We find that the free peptide segment rapidly interconverts between ordered and disordered states with significant populations of the conformations that are seen in the complexed states. The underlying global folding-binding landscape points to a synergistic mechanism in which recognition is dictated via long range electrostatic recognition which results in the formation of reactive structures as far away as 10 Å, and binding proceeds with the steering of selected conformations followed by induced folding at the target surface or within a close range. PMID:27030593

  13. Thermal Modification of Silicate Materials on Flash-heated Sulfide IDPs: The First Clues for Chemically Controlled, Early Silicate Mineral Evolution

    NASA Technical Reports Server (NTRS)

    Rietmeijer, F. J. M.

    2002-01-01

    Variable Ca-compositions of flash heated ferromagnesiosilica materials on massive sulfide IDPs provide the first clues for chemically controlled nucleation of pyroxenes during the earliest stages of silicate mineral evolution in solar nebula dust. Additional information is contained in the original extended abstract.

  14. Heat-Treatment of MgSiO Smokes of Astrophysical Interest: Possible Implications for Olivine-Pyroxene-Silica Assemblages in Chondritic Aggregate IDPs

    NASA Technical Reports Server (NTRS)

    Rietmeijer, F. J. M.; Nuth, J. A., III; Hallenbeck, S. L.

    2001-01-01

    Anhydrous silicates in coarse-grained ferromagnesiosilica principal components (PCs) formed during atmospheric entry flash-heating also constrain the astromineralogy of astrophysical dust. This is because of the unique closed-system behavior of these PCs in chondritic aggregate interplanetary dust particles (IDPs). Additional information is contained in the original extended abstract.

  15. Mid-IR, Far-IR, Raman micro-spectroscopy, and FESEM-EDX study of IDP L2021C5: Clues to its origin

    NASA Astrophysics Data System (ADS)

    Brunetto, R.; Borg, J.; Dartois, E.; Rietmeijer, F. J. M.; Grossemy, F.; Sandt, C.; Le Sergeant d'Hendecourt, L.; Rotundi, A.; Dumas, P.; Djouadi, Z.; Jamme, F.

    2011-04-01

    Interplanetary Dust Particles (IDPs) are potentially of cometary origin. They may therefore provide important clues to a better understanding of the early Solar System physical and chemical conditions. A chondritic porous aggregate IDP (named L2021C5) was analyzed using mid to far FTIR (2-60 μm) micro-spectroscopy, Raman micro-spectroscopy, field-emission scanning electron microscopy (FESEM) and energy dispersive X-ray (EDX) analyses. The IDP was pressed between diamond windows to increase the quality of the spectral data by overcoming the diffraction limitation and minimizing light scattering effects from particles of a global size similar to the wavelength of the observation. This combination of techniques has enabled a mineralogical, organic and compositional description of the compressed particle. The IR spectra show that in L2021C5 amorphous silicates are more abundant than crystalline ones, and that the crystalline component is richer in olivine than in pyroxene. The composition and distribution of these inorganic components match very well the small silicate grains emission observed for comet Hale-Bopp from ISO-SWS spectra. Raman spectroscopy has allowed the detection of carbonaceous structures displaying different degrees of order, covering almost the whole range observed so far for IDPs. The combination of the three analytical techniques indicates that L2021C5 is a low-Ca, chondritic porous aggregate that experienced only mild flash heating on atmospheric entry, as indicated by the disordered carbon properties, the Fe/S atomic ratio of sulfides, the absence of Na depletion, and the small depletion of S. Based on a plausible cometary origin and on the estimated low entry velocity, we suggest that this IDP came from the Zodiacal cloud that is dominated by dust from Jupiter-Family comets.

  16. Transcriptome Analysis of the Interferon-Signature Defining the Autoimmune Process of Sjögren’s Syndrome

    PubMed Central

    Peck, A. B.; Nguyen, C. Q.

    2015-01-01

    Sjögren’s syndrome (SS) of humans and SS-like (SjS-like) diseases in mouse models are characterized by chronic immune attacks against the salivary and lacrimal glands leading to exocrine dysfunction. One characteristic of SS and SjS-like diseases repeatedly observed is a strong upregulated expression of both the type I (α/β) and type II (γ) interferons (IFNs). In addition, recent global transcriptome studies have identified a variety of IFN-stimulated gene (ISG) transcripts differentially expressed in tissues of SS patients and mouse models exhibiting SjS-like disease. Analyses of these transcriptome databases indicate that the sets of differentially expressed genes are highly restricted, suggesting that there is a unique specificity in ISGs activated (or suppressed) during development and onset of disease. As a result, these observations have led to both SS and SjS-like diseases being designated as ‘interferon-signature’ diseases. While SS and SjS-like diseases may be designated as such, very little effort has been made to determine what an interferon-signature might signify relative to autoinflammation and whether it might point directly to an underlying etiopathological mechanism. Here, we review these limited data and provide a model of how the products of these genes interact molecularly and biologically to define critical details of SS pathology. PMID:22703193

  17. Predicting individual differences in decision-making process from signature movement styles: an illustrative study of leaders

    PubMed Central

    Connors, Brenda L.; Rende, Richard; Colton, Timothy J.

    2013-01-01

    There has been a surge of interest in examining the utility of methods for capturing individual differences in decision-making style. We illustrate the potential offered by Movement Pattern Analysis (MPA), an observational methodology that has been used in business and by the US Department of Defense to record body movements that provide predictive insight into individual differences in decision-making motivations and actions. Twelve military officers participated in an intensive 2-h interview that permitted detailed and fine-grained observation and coding of signature movements by trained practitioners using MPA. Three months later, these subjects completed four hypothetical decision-making tasks in which the amount of information sought out before coming to a decision, as well as the time spent on the tasks, were under the partial control of the subject. A composite MPA indicator of how a person allocates decision-making actions and motivations to balance both Assertion (exertion of tangible movement effort on the environment to make something occur) and Perspective (through movements that support shaping in the body to perceive and create a suitable viewpoint for action) was highly correlated with the total number of information draws and total response time—individuals high on Assertion reached for less information and had faster response times than those high on Perspective. Discussion focuses on the utility of using movement-based observational measures to capture individual differences in decision-making style and the implications for application in applied settings geared toward investigations of experienced leaders and world statesmen where individuality rules the day. PMID:24069012

  18. Electrical signature of modern and ancient tectonic processes in the crust of the Atlas mountains of Morocco

    NASA Astrophysics Data System (ADS)

    Ledo, Juanjo; Jones, Alan G.; Siniscalchi, Agata; Campanyà, Joan; Kiyan, Duygu; Romano, Gerardo; Rouai, Mohamed; TopoMed MT Team

    2011-04-01

    The Atlas Mountains in Morocco are considered as type examples of intracontinental mountain chains, with high topography that contrasts with moderate crustal shortening and thickening. Whereas recent geological studies and geodynamic modelling suggest the existence of dynamic topography to explain this apparent contradiction, there is a lack of modern geophysical data at the crustal scale to corroborate this hypothesis. To address this deficiency, magnetotelluric data were recently acquired that image the electrical resistivity distribution of the crust from the Middle Atlas to the Anti-Atlas, crossing the tabular Moulouya plain and the High Atlas. All tectonic units show different, distinct and unique electrical signatures throughout the crust reflecting the tectonic history of development of each one. In the upper crust, electrical resistivity values and geometries can be associated to sediment sequences in the Moulouya and Anti-Atlas and to crustal scale fault systems in the High Atlas developed likely during Cenozoic times. In the lower crust, the low resistivity anomaly found below the Moulouya plain, together with other geophysical (low velocity anomaly, lack of earthquakes and minimum Bouguer anomaly) and geochemical (Neogene-Quaternary intraplate alkaline volcanic fields) evidences, infer the existence of a small degree of partial melt at the base of the crust. Resistivity values suggest a partial melt fraction of the order of 2-8%. The low resistivity anomaly found below the Anti-Atlas may be associated with a relict subduction of Precambrian oceanic sediments, or to precipitated minerals during the release of fluids from the mantle during the accretion of the Anti-Atlas to the West African Supercontinent during the Panafrican orogeny (ca. 685 Ma).

  19. Elucidating source processes of N2O fluxes following grassland-to-field-conversion using isotopologue signatures of soil-emitted N2O

    NASA Astrophysics Data System (ADS)

    Roth, G.; Giesemann, A.; Well, R.; Flessa, H.

    2012-04-01

    Conversion of grassland to arable land often causes enhanced nitrous oxide (N2O) emissions to the atmosphere. This is due to the tillage of the sward and subsequent decomposition of organic matter. Prediction of such effects is uncertain so far because emissions may differ depending on site and soil conditions. The processes of N2O turnover (nitrification, production by bacterial or fungal denitrifiers, bacterial reduction to N2) are difficult to identify, however. Isotopologue signatures of N2O such as δ18O, average δ15N (δ15Nbulk) and 15N site preference (SP = difference in δ15N between the central and peripheral N positions of the asymmetric N2O molecule) can be used to characterize N2O turnover processes using the known ranges of isotope effects of the various N2O pathways. We aim to evaluate the impact of grassland-to-field-conversion on N2O fluxes and the governing processes using isotopic signatures of emitted N2O. At two sites, in Kleve (North Rhine-Westphalia, Germany, conventional farming) and Trenthorst (Schleswig-Holstein, Germany, organic farming), a four times replicated plot experiment with (i) mechanical conversion (ploughing, maize), (ii) chemical conversion (broadband herbicide, maize per direct seed) and (iii) continuous grassland as reference was started in April 2010. In Trenthorst we additionally established a (iv) field with continuous maize cultivation as further reference. Over a period of two years, mineral nitrogen (Nmin) content was measured weekly on soil samples taken from 0-10 cm and 10-30 cm depth. Soil water content and N2O emissions were measured weekly as well. Gas samples were collected using a closed chamber system. Isotope ratio mass spectrometry was carried out on gas samples from selected high flux events to determine δ18O, δ15Nbulk and SP of N2O. δ18O and SP of N2O exhibited a relatively large range (32 to 72 ‰ and 6 to 34 ‰, respectively) indicating highly variable process dynamics. The data-set is grouped

  20. Intrusion detection using secure signatures

    DOEpatents

    Nelson, Trent Darnel; Haile, Jedediah

    2014-09-30

    A method and device for intrusion detection using secure signatures comprising capturing network data. A search hash value, value employing at least one one-way function, is generated from the captured network data using a first hash function. The presence of a search hash value match in a secure signature table comprising search hash values and an encrypted rule is determined. After determining a search hash value match, a decryption key is generated from the captured network data using a second hash function, a hash function different form the first hash function. One or more of the encrypted rules of the secure signatures table having a hash value equal to the generated search hash value are then decrypted using the generated decryption key. The one or more decrypted secure signature rules are then processed for a match and one or more user notifications are deployed if a match is identified.

  1. Developing composite signatures

    NASA Astrophysics Data System (ADS)

    Hawley, Chadwick T.; Carpenter, Tom; Cappelaere, Patrice G.; Frye, Stu; Lemoigne-Stewart, Jacqueline J.; Mandle, Dan; Montgomery, Sarah; Williams-Bess, Autumn

    2011-06-01

    A composite signature is a group of signatures that are related in such a way to more completely or further define a target or operational endeavor at a higher fidelity. This paper explores the merits of using composite signatures, in lieu of waiting for opportunities for the more elusive diagnostic signatures, to satisfy key essential elements of information Keywords: signature, composite signature, civil disaster (EEI) associated with civil disaster-related problems. It discusses efforts to refine composite signature development methodology and quantify the relative value of composite vs. diagnostic signatures. The objectives are to: 1) investigate and develop innovative composite signatures associated with civil disasters, including physical, chemical and pattern/behavioral; 2) explore the feasibility of collecting representative composite signatures using current and emerging intelligence, surveillance, and reconnaissance (ISR) collection architectures leveraging civilian and commercial architectures; and 3) collaborate extensively with scientists and engineers from U.S. government organizations and laboratories, the defense industry, and academic institutions.

  2. Discovery of a Novel Immune Gene Signature with Profound Prognostic Value in Colorectal Cancer: A Model of Cooperativity Disorientation Created in the Process from Development to Cancer

    PubMed Central

    An, Ning; Shi, Xiaoyu; Zhang, Yueming; Lv, Ning; Feng, Lin; Di, Xuebing; Han, Naijun; Wang, Guiqi

    2015-01-01

    Immune response-related genes play a major role in colorectal carcinogenesis by mediating inflammation or immune-surveillance evasion. Although remarkable progress has been made to investigate the underlying mechanism, the understanding of the complicated carcinogenesis process was enormously hindered by large-scale tumor heterogeneity. Development and carcinogenesis share striking similarities in their cellular behavior and underlying molecular mechanisms. The association between embryonic development and carcinogenesis makes embryonic development a viable reference model for studying cancer thereby circumventing the potentially misleading complexity of tumor heterogeneity. Here we proposed that the immune genes, responsible for intra-immune cooperativity disorientation (defined in this study as disruption of developmental expression correlation patterns during carcinogenesis), probably contain untapped prognostic resource of colorectal cancer. In this study, we determined the mRNA expression profile of 137 human biopsy samples, including samples from different stages of human colonic development, colorectal precancerous progression and colorectal cancer samples, among which 60 were also used to generate miRNA expression profile. We originally established Spearman correlation transition model to quantify the cooperativity disorientation associated with the transition from normal to precancerous to cancer tissue, in conjunction with miRNA-mRNA regulatory network and machine learning algorithm to identify genes with prognostic value. Finally, a 12-gene signature was extracted, whose prognostic value was evaluated using Kaplan–Meier survival analysis in five independent datasets. Using the log-rank test, the 12-gene signature was closely related to overall survival in four datasets (GSE17536, n = 177, p = 0.0054; GSE17537, n = 55, p = 0.0039; GSE39582, n = 562, p = 0.13; GSE39084, n = 70, p = 0.11), and significantly associated with disease-free survival in four

  3. Discovery of a Novel Immune Gene Signature with Profound Prognostic Value in Colorectal Cancer: A Model of Cooperativity Disorientation Created in the Process from Development to Cancer.

    PubMed

    An, Ning; Shi, Xiaoyu; Zhang, Yueming; Lv, Ning; Feng, Lin; Di, Xuebing; Han, Naijun; Wang, Guiqi; Cheng, Shujun; Zhang, Kaitai

    2015-01-01

    Immune response-related genes play a major role in colorectal carcinogenesis by mediating inflammation or immune-surveillance evasion. Although remarkable progress has been made to investigate the underlying mechanism, the understanding of the complicated carcinogenesis process was enormously hindered by large-scale tumor heterogeneity. Development and carcinogenesis share striking similarities in their cellular behavior and underlying molecular mechanisms. The association between embryonic development and carcinogenesis makes embryonic development a viable reference model for studying cancer thereby circumventing the potentially misleading complexity of tumor heterogeneity. Here we proposed that the immune genes, responsible for intra-immune cooperativity disorientation (defined in this study as disruption of developmental expression correlation patterns during carcinogenesis), probably contain untapped prognostic resource of colorectal cancer. In this study, we determined the mRNA expression profile of 137 human biopsy samples, including samples from different stages of human colonic development, colorectal precancerous progression and colorectal cancer samples, among which 60 were also used to generate miRNA expression profile. We originally established Spearman correlation transition model to quantify the cooperativity disorientation associated with the transition from normal to precancerous to cancer tissue, in conjunction with miRNA-mRNA regulatory network and machine learning algorithm to identify genes with prognostic value. Finally, a 12-gene signature was extracted, whose prognostic value was evaluated using Kaplan-Meier survival analysis in five independent datasets. Using the log-rank test, the 12-gene signature was closely related to overall survival in four datasets (GSE17536, n = 177, p = 0.0054; GSE17537, n = 55, p = 0.0039; GSE39582, n = 562, p = 0.13; GSE39084, n = 70, p = 0.11), and significantly associated with disease-free survival in four

  4. Process-Based Species Pools Reveal the Hidden Signature of Biotic Interactions Amid the Influence of Temperature Filtering.

    PubMed

    Lessard, Jean-Philippe; Weinstein, Ben G; Borregaard, Michael K; Marske, Katharine A; Martin, Danny R; McGuire, Jimmy A; Parra, Juan L; Rahbek, Carsten; Graham, Catherine H

    2016-01-01

    A persistent challenge in ecology is to tease apart the influence of multiple processes acting simultaneously and interacting in complex ways to shape the structure of species assemblages. We implement a heuristic approach that relies on explicitly defining species pools and permits assessment of the relative influence of the main processes thought to shape assemblage structure: environmental filtering, dispersal limitations, and biotic interactions. We illustrate our approach using data on the assemblage composition and geographic distribution of hummingbirds, a comprehensive phylogeny and morphological traits. The implementation of several process-based species pool definitions in null models suggests that temperature-but not precipitation or dispersal limitation-acts as the main regional filter of assemblage structure. Incorporating this environmental filter directly into the definition of assemblage-specific species pools revealed an otherwise hidden pattern of phylogenetic evenness, indicating that biotic interactions might further influence hummingbird assemblage structure. Such hidden patterns of assemblage structure call for a reexamination of a multitude of phylogenetic- and trait-based studies that did not explicitly consider potentially important processes in their definition of the species pool. Our heuristic approach provides a transparent way to explore patterns and refine interpretations of the underlying causes of assemblage structure. PMID:27277404

  5. β decay of nuclei around 90Se: Search for signatures of a N=56 subshell closure relevant to the r process

    NASA Astrophysics Data System (ADS)

    Quinn, M.; Aprahamian, A.; Pereira, J.; Surman, R.; Arndt, O.; Baumann, T.; Becerril, A.; Elliot, T.; Estrade, A.; Galaviz, D.; Ginter, T.; Hausmann, M.; Hennrich, S.; Kessler, R.; Kratz, K.-L.; Lorusso, G.; Mantica, P. F.; Matos, M.; Montes, F.; Pfeiffer, B.; Portillo, M.; Schatz, H.; Schertz, F.; Schnorrenberger, L.; Smith, E.; Stolz, A.; Walters, W. B.; Wöhr, A.

    2012-03-01

    Background: Nuclear structure plays a significant role on the rapid neutron capture process (r process) since shapes evolve with the emergence of shells and subshells. There was some indication in neighboring nuclei that we might find examples of a new N=56 subshell, which may give rise to a doubly magic 3490Se56 nucleus.Purpose: β-decay half-lives of nuclei around 90Se have been measured to determine if this nucleus has in fact a doubly magic character.Method: The fragmentation of a 136Xe beam at the National Superconducting Cyclotron Laboratory at Michigan State University was used to create a cocktail of nuclei in the A=90 region.Results: We have measured the half-lives of 22 nuclei near the r-process path in the A=90 region. The half-lives of 88As and 90Se have been measured for the first time. The values were compared with theoretical predictions in the search for nuclear-deformation signatures of a N=56 subshell, and its possible role in the emergence of a potential doubly magic 90Se. The impact of such hypothesis on the synthesis of heavy nuclei, particularly in the production of Sr, Y, and Zr elements was investigated with a weak r-process network.Conclusions: The new half-lives agree with results obtained from a standard global QRPA model used in r-process calculations, indicating that 90Se has a quadrupole shape incompatible with a closed N=56 subshell in this region. The impact of the measured 90Se half-life in comparison with a former theoretical predication associated with a spherical half-life on the weak r process is shown to be strong.

  6. Minority Language Development and Literacy among Internally Displaced Persons (IDPs), Refugees, and Wartime Communities

    ERIC Educational Resources Information Center

    Yoder, Joan Bomberger

    2008-01-01

    This article describes how minority language development and literacy activities were facilitated in a wartime context for Southern Sudanese language groups, particularly through the use of workshops. It also presents the voices of the language speakers themselves as they reflect on this process. A background discussion considers the importance of…

  7. Gene expression signatures in motor neurone disease fibroblasts reveal dysregulation of metabolism, hypoxia-response and RNA processing functions

    PubMed Central

    Raman, R; Allen, S P; Goodall, E F; Kramer, S; Ponger, L-L; Heath, P R; Milo, M; Hollinger, H C; Walsh, T; Highley, J R; Olpin, S; McDermott, C J; Shaw, P J; Kirby, J

    2015-01-01

    Aims Amyotrophic lateral sclerosis (ALS) and primary lateral sclerosis (PLS) are two syndromic variants within the motor neurone disease spectrum. As PLS and most ALS cases are sporadic (SALS), this limits the availability of cellular models for investigating pathogenic mechanisms and therapeutic targets. The aim of this study was to use gene expression profiling to evaluate fibroblasts as cellular models for SALS and PLS, to establish whether dysregulated biological processes recapitulate those seen in the central nervous system and to elucidate pathways that distinguish the clinically defined variants of SALS and PLS. Methods Microarray analysis was performed on fibroblast RNA and differentially expressed genes identified. Genes in enriched biological pathways were validated by quantitative PCR and functional assays performed to establish the effect of altered RNA levels on the cellular processes. Results Gene expression profiling demonstrated that whilst there were many differentially expressed genes in common between SALS and PLS fibroblasts, there were many more expressed specifically in the SALS fibroblasts, including those involved in RNA processing and the stress response. Functional analysis of the fibroblasts confirmed a significant decrease in miRNA production and a reduced response to hypoxia in SALS fibroblasts. Furthermore, metabolic gene changes seen in SALS, many of which were also evident in PLS fibroblasts, resulted in dysfunctional cellular respiration. Conclusions The data demonstrate that fibroblasts can act as cellular models for ALS and PLS, by establishing the transcriptional changes in known pathogenic pathways that confer subsequent functional effects and potentially highlight targets for therapeutic intervention. PMID:24750211

  8. Signatures of nonthermal melting.

    PubMed

    Zier, Tobias; Zijlstra, Eeuwe S; Kalitsov, Alan; Theodonis, Ioannis; Garcia, Martin E

    2015-09-01

    Intense ultrashort laser pulses can melt crystals in less than a picosecond but, in spite of over thirty years of active research, for many materials it is not known to what extent thermal and nonthermal microscopic processes cause this ultrafast phenomenon. Here, we perform ab-initio molecular-dynamics simulations of silicon on a laser-excited potential-energy surface, exclusively revealing nonthermal signatures of laser-induced melting. From our simulated atomic trajectories, we compute the decay of five structure factors and the time-dependent structure function. We demonstrate how these quantities provide criteria to distinguish predominantly nonthermal from thermal melting. PMID:26798822

  9. Signatures of nonthermal melting

    PubMed Central

    Zier, Tobias; Zijlstra, Eeuwe S.; Kalitsov, Alan; Theodonis, Ioannis; Garcia, Martin E.

    2015-01-01

    Intense ultrashort laser pulses can melt crystals in less than a picosecond but, in spite of over thirty years of active research, for many materials it is not known to what extent thermal and nonthermal microscopic processes cause this ultrafast phenomenon. Here, we perform ab-initio molecular-dynamics simulations of silicon on a laser-excited potential-energy surface, exclusively revealing nonthermal signatures of laser-induced melting. From our simulated atomic trajectories, we compute the decay of five structure factors and the time-dependent structure function. We demonstrate how these quantities provide criteria to distinguish predominantly nonthermal from thermal melting. PMID:26798822

  10. A hybrid approach identifies metabolic signatures of high-producers for chinese hamster ovary clone selection and process optimization.

    PubMed

    Popp, Oliver; Müller, Dirk; Didzus, Katharina; Paul, Wolfgang; Lipsmeier, Florian; Kirchner, Florian; Niklas, Jens; Mauch, Klaus; Beaucamp, Nicola

    2016-09-01

    In-depth characterization of high-producer cell lines and bioprocesses is vital to ensure robust and consistent production of recombinant therapeutic proteins in high quantity and quality for clinical applications. This requires applying appropriate methods during bioprocess development to enable meaningful characterization of CHO clones and processes. Here, we present a novel hybrid approach for supporting comprehensive characterization of metabolic clone performance. The approach combines metabolite profiling with multivariate data analysis and fluxomics to enable a data-driven mechanistic analysis of key metabolic traits associated with desired cell phenotypes. We applied the methodology to quantify and compare metabolic performance in a set of 10 recombinant CHO-K1 producer clones and a host cell line. The comprehensive characterization enabled us to derive an extended set of clone performance criteria that not only captured growth and product formation, but also incorporated information on intracellular clone physiology and on metabolic changes during the process. These criteria served to establish a quantitative clone ranking and allowed us to identify metabolic differences between high-producing CHO-K1 clones yielding comparably high product titers. Through multivariate data analysis of the combined metabolite and flux data we uncovered common metabolic traits characteristic of high-producer clones in the screening setup. This included high intracellular rates of glutamine synthesis, low cysteine uptake, reduced excretion of aspartate and glutamate, and low intracellular degradation rates of branched-chain amino acids and of histidine. Finally, the above approach was integrated into a workflow that enables standardized high-content selection of CHO producer clones in a high-throughput fashion. In conclusion, the combination of quantitative metabolite profiling, multivariate data analysis, and mechanistic network model simulations can identify metabolic

  11. Ballistic Signature Identification System Study

    NASA Technical Reports Server (NTRS)

    1976-01-01

    The first phase of a research project directed toward development of a high speed automatic process to be used to match gun barrel signatures imparted to fired bullets was documented. An optical projection technique has been devised to produce and photograph a planar image of the entire signature, and the phototransparency produced is subjected to analysis using digital Fourier transform techniques. The success of this approach appears to be limited primarily by the accuracy of the photographic step since no significant processing limitations have been encountered.

  12. Biomarker Sensors and Method for Multi-Color Imaging and Processing of Single-Molecule Life Signatures

    NASA Technical Reports Server (NTRS)

    Wade, Lawrence A. (Inventor); Collier, Charles Patrick (Inventor)

    2013-01-01

    The invention is a device including array of active regions for use in reacting one or more species in at least two of the active regions in a sequential process, e.g., sequential reactions. The device has a transparent substrate member, which has a surface region and a silane material overlying the surface region. A first active region overlies a first portion of the silane material. The first region has a first dimension of less than 1 micron in size and has first molecules capable of binding to the first portion of the silane material. A second active region overlies a second portion of the silane material. The second region has a second dimension of less than 1 micron in size, second molecules capable of binding to the second portion of the active region, and a spatial distance separates the first active region and the second active region.

  13. Anonymous Signatures Revisited

    NASA Astrophysics Data System (ADS)

    Saraswat, Vishal; Yun, Aaram

    We revisit the notion of the anonymous signature, first formalized by Yang, Wong, Deng and Wang [10], and then further developed by Fischlin [4] and Zhang and Imai [11]. We present a new formalism of anonymous signature, where instead of the message, a part of the signature is withheld to maintain anonymity. We introduce the notion unpretendability to guarantee infeasibility for someone other than the correct signer to pretend authorship of the message and signature. Our definition retains applicability for all previous applications of the anonymous signature, provides stronger security, and is conceptually simpler. We give a generic construction from any ordinary signature scheme, and also show that the short signature scheme by Boneh and Boyen [2] can be naturally regarded as such a secure anonymous signature scheme according to our formalism.

  14. Amorphous SiO2 surface models: energetics of the dehydroxylation process, strain, ab initio atomistic thermodynamics and IR spectroscopic signatures.

    PubMed

    Comas-Vives, Aleix

    2016-03-14

    In this contribution, realistic amorphous SiO2 models of 2.1 × 2.1 nm with silanol densities ranging 1.1-7.2 OH per nm(2) are obtained by means of ab initio calculations via the dehydroxylation of a fully hydroxylated silica surface. The dehydroxyation process is considered to take place via direct condensation of adjacent silanol groups and silica migration steps. The latter reconstructions are needed in order to obtain highly dehydroxylated silica surfaces with favorable energetics and without the formation of defects. The obtained surface phase diagram of different silica models as a function of temperature and PH2O is able to correctly describe the silanol density under different conditions, and the IR spectroscopic signatures of the silanols are in qualitative agreement with the experiment. The amorphous silica models presented here have a high degree of heterogeneity as found from the big variability obtained in the energetics of the dehydroxylation steps. It was also found that the resulting average Si-O distance of the newly formed siloxane bridges serves as a descriptor of the strain introduced in the silica surface. All these factors can be crucial in order to simulate the activity of catalysts grafted onto silica with different silanol densities, especially the one containing ca. 1 OH per nm(2), which can serve as a model for the SiO2 surface pretreated under high vacuum and at 700 °C. PMID:26898649

  15. Mutations in the nucleotide binding domain 1 signature motif region rescue processing and functional defects of cystic fibrosis transmembrane conductance regulator delta f508.

    PubMed

    DeCarvalho, Ana C V; Gansheroff, Lisa J; Teem, John L

    2002-09-27

    The gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR), an ATP binding cassette (ABC) transporter that functions as a phosphorylation- and nucleotide-regulated chloride channel, is mutated in cystic fibrosis (CF) patients. Deletion of a phenylalanine at amino acid position 508 (DeltaF508) in the first nucleotide binding domain (NBD1) is the most prevalent CF-causing mutation and results in defective protein processing and reduced CFTR function, leading to chloride impermeability in CF epithelia and heterologous systems. Using a STE6/CFTRDeltaF508 chimera system in yeast, we isolated two novel DeltaF508 revertant mutations, I539T and G550E, proximal to and within the conserved ABC signature motif of NBD1, respectively. Western blot and functional analysis in mammalian cells indicate that mutations I539T and G550E each partially rescue the CFTRDeltaF508 defect. Furthermore, a combination of both revertant mutations resulted in a 38-fold increase in CFTRDeltaF508-mediated chloride current, representing 29% of wild type channel activity. The G550E mutation increased the sensitivity of CFTRDeltaF508 and wild type CFTR to activation by cAMP agonists and blocked the enhancement of CFTRDeltaF508 channel activity by 2 mm 3-isobutyl-1-methylxanthine. The data show that the DeltaF508 defect can be significantly rescued by second-site mutations in the nucleotide binding domain 1 region, that includes the LSGGQ consensus motif. PMID:12110684

  16. Simulating realistic predator signatures in quantitative fatty acid signature analysis

    USGS Publications Warehouse

    Bromaghin, Jeffrey F.

    2015-01-01

    Diet estimation is an important field within quantitative ecology, providing critical insights into many aspects of ecology and community dynamics. Quantitative fatty acid signature analysis (QFASA) is a prominent method of diet estimation, particularly for marine mammal and bird species. Investigators using QFASA commonly use computer simulation to evaluate statistical characteristics of diet estimators for the populations they study. Similar computer simulations have been used to explore and compare the performance of different variations of the original QFASA diet estimator. In both cases, computer simulations involve bootstrap sampling prey signature data to construct pseudo-predator signatures with known properties. However, bootstrap sample sizes have been selected arbitrarily and pseudo-predator signatures therefore may not have realistic properties. I develop an algorithm to objectively establish bootstrap sample sizes that generates pseudo-predator signatures with realistic properties, thereby enhancing the utility of computer simulation for assessing QFASA estimator performance. The algorithm also appears to be computationally efficient, resulting in bootstrap sample sizes that are smaller than those commonly used. I illustrate the algorithm with an example using data from Chukchi Sea polar bears (Ursus maritimus) and their marine mammal prey. The concepts underlying the approach may have value in other areas of quantitative ecology in which bootstrap samples are post-processed prior to their use.

  17. Direct and inverse auger processes in InAs nanocrystals: can the decay signature of a trion be mistaken for carrier multiplication?

    PubMed

    Califano, Marco

    2009-09-22

    A complete and detailed theoretical investigation of the main processes involved in the controversial detection and quantification of carrier multiplication (CM) is presented, providing a coherent and comprehensive picture of excited state relaxation in InAs nanocrystals (NCs). The observed rise and decay times of the 1S transient bleach are reproduced, in the framework of the Auger model, using an atomistic semiempirical pseudopotential method, achieving excellent agreement with experiment. The CM time constants for small core-only and core/shell nanocrystals are obtained as a function of the excitation energy, assuming an impact-ionization-like process. The resulting lifetimes at energies close to the observed CM onset are consistent with the upper limits deduced experimentally from PbSe and CdSe samples. Most interestingly, as the Auger recombination lifetimes calculated for charged excitons are found to be of a similar order of magnitude to those computed for biexcitons, both species are expected to exhibit the fast decay component in NC population dynamics so far attributed exclusively to the presence of biexcitons and therefore identified as the signature of CM occurrence in high-energy low-pump-fluence spectroscopic studies. However, the ratio between trions and biexcitons time constants is found to be larger than the typical experimental accuracy. It is therefore concluded that, in InAs NCs, it should be experimentally possible to discriminate between the two species and that the origin of the observed discrepancies in CM yields is unlikely to lay in the presence of charged excitons. PMID:19689121

  18. Signature Visualization of Software Binaries

    SciTech Connect

    Panas, T

    2008-07-01

    In this paper we present work on the visualization of software binaries. In particular, we utilize ROSE, an open source compiler infrastructure, to pre-process software binaries, and we apply a landscape metaphor to visualize the signature of each binary (malware). We define the signature of a binary as a metric-based layout of the functions contained in the binary. In our initial experiment, we visualize the signatures of a series of computer worms that all originate from the same line. These visualizations are useful for a number of reasons. First, the images reveal how the archetype has evolved over a series of versions of one worm. Second, one can see the distinct changes between version. This allows the viewer to form conclusions about the development cycle of a particular worm.

  19. Signature molecular descriptor : advanced applications.

    SciTech Connect

    Visco, Donald Patrick, Jr.

    2010-04-01

    In this work we report on the development of the Signature Molecular Descriptor (or Signature) for use in the solution of inverse design problems as well as in highthroughput screening applications. The ultimate goal of using Signature is to identify novel and non-intuitive chemical structures with optimal predicted properties for a given application. We demonstrate this in three studies: green solvent design, glucocorticoid receptor ligand design and the design of inhibitors for Factor XIa. In many areas of engineering, compounds are designed and/or modified in incremental ways which rely upon heuristics or institutional knowledge. Often multiple experiments are performed and the optimal compound is identified in this brute-force fashion. Perhaps a traditional chemical scaffold is identified and movement of a substituent group around a ring constitutes the whole of the design process. Also notably, a chemical being evaluated in one area might demonstrate properties very attractive in another area and serendipity was the mechanism for solution. In contrast to such approaches, computer-aided molecular design (CAMD) looks to encompass both experimental and heuristic-based knowledge into a strategy that will design a molecule on a computer to meet a given target. Depending on the algorithm employed, the molecule which is designed might be quite novel (re: no CAS registration number) and/or non-intuitive relative to what is known about the problem at hand. While CAMD is a fairly recent strategy (dating to the early 1980s), it contains a variety of bottlenecks and limitations which have prevented the technique from garnering more attention in the academic, governmental and industrial institutions. A main reason for this is how the molecules are described in the computer. This step can control how models are developed for the properties of interest on a given problem as well as how to go from an output of the algorithm to an actual chemical structure. This report

  20. Astronomical and Meteoritic Evidence for the Nature of Interstellar Dust and Its Processing in Protoplanetary Disks

    NASA Astrophysics Data System (ADS)

    Alexander, C. M. O'd.; Boss, A. P.; Keller, L. P.; Nuth, J. A.; Weinberger, A.

    Here we compare the astronomical and meteoritic evidence for the nature and origin of interstellar dust, and how it is processed in protoplanetary disks. The relative abundances of circumstellar grains in meteorites and interplanetary dust particles (IDPs) are broadly consistent with most astronomical estimates of galactic dust production, although graphite/amorphous C is highly underabundant. The major carbonaceous component in meteorites and IDPs is an insoluble organic material (IOM) that probably formed in the interstellar medium, but a solar origin cannot be ruled out. GEMS (glass with embedded metal and sulfide) that are isotopically solar within error are the best candidates for interstellar silicates, but it is also possible that they are solar system condensates. No dust from young stellar objects has been identified in IDPs, but it is difficult to differentiate them from solar system material or indeed some circumstellar condensates. The crystalline silicates in IDPs are mostly solar condensates, with lesser amounts of annealed GEMS. The IOM abundances in IDPs are roughly consistent with the degree of processing indicated by their crystallinity if the processed material was ISM dust. The IOM contents of meteorites are much lower, suggesting that there was a gradient in dust processing in the solar system. The microstructure of much of the pyroxene in IDPs suggests that it formed at temperatures >1258 K and cooled relatively rapidly (~1000 K/h). This cooling rate favors shock heating rather than radial transport of material annealed in the hot inner disk as the mechanism for producing crystalline dust in comets and IDPs. Shock heating is also a likely mechanism for producing chondrules in meteorites, but the dust was probably heated at a different time and/or location to chondrules.

  1. Comparison of Nickel XANES Spectra and Elemental Maps from a Ureilite, a LL3.8 Ordinary Chondrite, Two Carbonaceous Chondrites and Two Large Cluster IDPs

    NASA Technical Reports Server (NTRS)

    Wirick, S.; Flynn, G. J.; Sutton, S.; Zolensky, M. E.

    2014-01-01

    Nickel in the extraterrestrial world is commonly found in both Fe-Ni sulfide and Fe-Ni met-al forms [1] and in the pure metal state in the interior of iron meteorites where it is not easily oxidized. Ni is also found in olivine, pyroxene and glasses and in some melts the partitioning of Ni between the olivines and glass is controlled by the amount of S in the melt [2]. Its most common valence state is Ni(2+) but Ni also occurs as Ni(0), Ni(+), and Ni(3+) and rarely as Ni(2-), Ni(1-) and Ni(4+) [3]. It's valence state in olivines is Ni(2+) in octa-hedral coordination on the M1 site and rarely on the M2 site.[4]. The chemical sensitivity of X-ray absorp-tion near-edge structure (XANES) spectroscopy is well established and can be used to determine not only va-lence states but also coordination sites [5]. We report here Ni XANES spectroscopy and elemental maps collected from 2 carbonaceous chondrites, 2 large clus-ter IDPs, 1 ureilite and 1 LL3 orginary chondrite.Using XANES it may be possible to find a common trait in the large cluster IDPs that will also be found in mete-orite samples.

  2. Real time gamma-ray signature identifier

    DOEpatents

    Rowland, Mark; Gosnell, Tom B.; Ham, Cheryl; Perkins, Dwight; Wong, James

    2012-05-15

    A real time gamma-ray signature/source identification method and system using principal components analysis (PCA) for transforming and substantially reducing one or more comprehensive spectral libraries of nuclear materials types and configurations into a corresponding concise representation/signature(s) representing and indexing each individual predetermined spectrum in principal component (PC) space, wherein an unknown gamma-ray signature may be compared against the representative signature to find a match or at least characterize the unknown signature from among all the entries in the library with a single regression or simple projection into the PC space, so as to substantially reduce processing time and computing resources and enable real-time characterization and/or identification.

  3. Nitrogen isotopes as indicators of streamflow generation processes in a headwater forested catchment: Focusing on atmospheric NO3- contribution using δ 18O signature

    NASA Astrophysics Data System (ADS)

    Ohte, N.; Sebestyen, S. D.; Doctor, D. H.; Wankel, S. D.; Shanley, J. B.; Kendall, C.; Boyer, E. W.

    2003-12-01

    To quantify the contributions of atmospheric nitrogen deposition and mechanisms of nitrate discharge to stream, nitrogen chemistry and isotopes (δ 15N and δ 18O of NO3-) of streamwater were studied as part of an ongoing study of nutrient dynamics at the Sleepers River Research Watershed in Vermont, USA. We employed novel analytical procedures for high throughput of NO3- isotopic measurements. The denitrifier method for measurement of δ 15N and δ 18O of NO3- requires a smaller volume of water samples than previously applied methods, thus it enables fine resolution analysis of isotopes for stream, well, and soil water samples. Samples were collected throughout the spring 2003 snowmelt. Snowmelt runoff was initiated in the middle of March and peaked at the end of the month. Then, the runoff rate decreased gradually through April and May, and responded to several storm events. The highest concentration of NO3- in the stream was observed at the beginning of snowmelt (the end of March), and thereafter it declined continuously. The temporal course of NO3- discharge process during snowmelt period was divided into four phases based on changes in the relationship between runoff rate and NO3- concentration. During the earliest phase (very low runoff rate and highest NO3- concentration) isotope signatures, especially δ 18O of NO3-, indicated higher contribution of the atmospherically derived NO3-, meaning that the direct discharge from snow pack was the dominant source of NO3- to the stream. This also suggested that streamwater consisted only of a small volume of groundwater discharge and melt water of the in-stream snow pack and/or stream-covering snow pack. The δ 15N and δ 18O isotope compositions of NO3- during the middle phase of snowmelt indicated that the contribution of the NO3- generated by nitrifiers in soil increased gradually accompanied with increase of groundwater level. These detailed descriptions in the changes of NO3- discharge during snowmelt events

  4. Digital Signature Management.

    ERIC Educational Resources Information Center

    Hassler, Vesna; Biely, Helmut

    1999-01-01

    Describes the Digital Signature Project that was developed in Austria to establish an infrastructure for applying smart card-based digital signatures in banking and electronic-commerce applications. Discusses the need to conform to international standards, an international certification infrastructure, and security features for a public directory…

  5. Electronic Signatures for Public Procurement across Europe

    NASA Astrophysics Data System (ADS)

    Ølnes, Jon; Andresen, Anette; Arbia, Stefano; Ernst, Markus; Hagen, Martin; Klein, Stephan; Manca, Giovanni; Rossi, Adriano; Schipplick, Frank; Tatti, Daniele; Wessolowski, Gesa; Windheuser, Jan

    The PEPPOL (Pan-European Public Procurement On-Line) project is a large scale pilot under the CIP programme of the EU, exploring electronic public procurement in a unified European market. An important element is interoperability of electronic signatures across borders, identified today as a major obstacle to cross-border procurement. PEPPOL will address use of signatures in procurement processes, in particular tendering but also post-award processes like orders and invoices. Signature policies, i.e. quality requirements and requirements on information captured in the signing process, will be developed. This as well as technical interoperability of e-signatures across Europe will finally be piloted in demonstrators starting late 2009 or early 2010.

  6. UV Signature Mutations †

    PubMed Central

    2014-01-01

    Sequencing complete tumor genomes and exomes has sparked the cancer field's interest in mutation signatures for identifying the tumor's carcinogen. This review and meta-analysis discusses signatures and their proper use. We first distinguish between a mutagen's canonical mutations – deviations from a random distribution of base changes to create a pattern typical of that mutagen – and the subset of signature mutations, which are unique to that mutagen and permit inference backward from mutations to mutagen. To verify UV signature mutations, we assembled literature datasets on cells exposed to UVC, UVB, UVA, or solar simulator light (SSL) and tested canonical UV mutation features as criteria for clustering datasets. A confirmed UV signature was: ≥60% of mutations are C→T at a dipyrimidine site, with ≥5% CC→TT. Other canonical features such as a bias for mutations on the non-transcribed strand or at the 3' pyrimidine had limited application. The most robust classifier combined these features with criteria for the rarity of non-UV canonical mutations. In addition, several signatures proposed for specific UV wavelengths were limited to specific genes or species; non-signature mutations induced by UV may cause melanoma BRAF mutations; and the mutagen for sunlight-related skin neoplasms may vary between continents. PMID:25354245

  7. An archaeal genomic signature

    NASA Technical Reports Server (NTRS)

    Graham, D. E.; Overbeek, R.; Olsen, G. J.; Woese, C. R.

    2000-01-01

    Comparisons of complete genome sequences allow the most objective and comprehensive descriptions possible of a lineage's evolution. This communication uses the completed genomes from four major euryarchaeal taxa to define a genomic signature for the Euryarchaeota and, by extension, the Archaea as a whole. The signature is defined in terms of the set of protein-encoding genes found in at least two diverse members of the euryarchaeal taxa that function uniquely within the Archaea; most signature proteins have no recognizable bacterial or eukaryal homologs. By this definition, 351 clusters of signature proteins have been identified. Functions of most proteins in this signature set are currently unknown. At least 70% of the clusters that contain proteins from all the euryarchaeal genomes also have crenarchaeal homologs. This conservative set, which appears refractory to horizontal gene transfer to the Bacteria or the Eukarya, would seem to reflect the significant innovations that were unique and fundamental to the archaeal "design fabric." Genomic protein signature analysis methods may be extended to characterize the evolution of any phylogenetically defined lineage. The complete set of protein clusters for the archaeal genomic signature is presented as supplementary material (see the PNAS web site, www.pnas.org).

  8. Traceable Ring Signature

    NASA Astrophysics Data System (ADS)

    Fujisaki, Eiichiro; Suzuki, Koutarou

    The ring signature allows a signer to leak secrets anonymously, without the risk of identity escrow. At the same time, the ring signature provides great flexibility: No group manager, no special setup, and the dynamics of group choice. The ring signature is, however, vulnerable to malicious or irresponsible signers in some applications, because of its anonymity. In this paper, we propose a traceable ring signature scheme. A traceable ring scheme is a ring signature except that it can restrict “excessive” anonymity. The traceable ring signature has a tag that consists of a list of ring members and an issue that refers to, for instance, a social affair or an election. A ring member can make any signed but anonymous opinion regarding the issue, but only once (per tag). If the member submits another signed opinion, possibly pretending to be another person who supports the first opinion, the identity of the member is immediately revealed. If the member submits the same opinion, for instance, voting “yes” regarding the same issue twice, everyone can see that these two are linked. The traceable ring signature can suit to many applications, such as an anonymous voting on a BBS. We formalize the security definitions for this primitive and show an efficient and simple construction in the random oracle model.

  9. Modeling the Lexical Morphology of Western Handwritten Signatures

    PubMed Central

    Diaz-Cabrera, Moises; Ferrer, Miguel A.; Morales, Aythami

    2015-01-01

    A handwritten signature is the final response to a complex cognitive and neuromuscular process which is the result of the learning process. Because of the many factors involved in signing, it is possible to study the signature from many points of view: graphologists, forensic experts, neurologists and computer vision experts have all examined them. Researchers study written signatures for psychiatric, penal, health and automatic verification purposes. As a potentially useful, multi-purpose study, this paper is focused on the lexical morphology of handwritten signatures. This we understand to mean the identification, analysis, and description of the signature structures of a given signer. In this work we analyze different public datasets involving 1533 signers from different Western geographical areas. Some relevant characteristics of signature lexical morphology have been selected, examined in terms of their probability distribution functions and modeled through a General Extreme Value distribution. This study suggests some useful models for multi-disciplinary sciences which depend on handwriting signatures. PMID:25860942

  10. Signature extension studies

    NASA Technical Reports Server (NTRS)

    Vincent, R. K.; Thomas, G. S.; Nalepka, R. F.

    1974-01-01

    The importance of specific spectral regions to signature extension is explored. In the recent past, the signature extension task was focused on the development of new techniques. Tested techniques are now used to investigate this spectral aspect of the large area survey. Sets of channels were sought which, for a given technique, were the least affected by several sources of variation over four data sets and yet provided good object class separation on each individual data set. Using sets of channels determined as part of this study, signature extension was accomplished between data sets collected over a six-day period and over a range of about 400 kilometers.

  11. Signatures of topological Josephson junctions

    NASA Astrophysics Data System (ADS)

    Peng, Yang; Pientka, Falko; Berg, Erez; Oreg, Yuval; von Oppen, Felix

    2016-08-01

    Quasiparticle poisoning and diabatic transitions may significantly narrow the window for the experimental observation of the 4 π -periodic dc Josephson effect predicted for topological Josephson junctions. Here, we show that switching-current measurements provide accessible and robust signatures for topological superconductivity which persist in the presence of quasiparticle poisoning processes. Such measurements provide access to the phase-dependent subgap spectrum and Josephson currents of the topological junction when incorporating it into an asymmetric SQUID together with a conventional Josephson junction with large critical current. We also argue that pump-probe experiments with multiple current pulses can be used to measure the quasiparticle poisoning rates of the topological junction. The proposed signatures are particularly robust, even in the presence of Zeeman fields and spin-orbit coupling, when focusing on short Josephson junctions. Finally, we also consider microwave excitations of short topological Josephson junctions which may complement switching-current measurements.

  12. Assessment of the Interstellar Processes Leading to Deuterium Enrichment in Meteoritic Organics

    NASA Technical Reports Server (NTRS)

    Sandford, Scott A.; Bernstein, Max P.; Dworkin, Jason P.; DeVincenzi, Donald L. (Technical Monitor)

    2001-01-01

    The presence of isotopic anomalies is the most unequivocal demonstration that meteoritic material contains circumstellar or interstellar components. In the case of organic compounds in meteorites and interplanetary dust particles (IDPs), the most useful isotopic tracer has been deuterium (D). We discuss four processes that are expected to lead to D enrichment in interstellar materials and describe how their unique characteristics can be used to assess their relative importance for the organics in meteorites. These enrichment processes are low temperature gas phase ion-molecule reactions, low temperature gas-grain reactions, gas phase unimolecular photodissociation, and ultraviolet photolysis in D-enriched ice mantles. Each of these processes is expected to be associated with distinct regiochemical signatures (D placement on the product molecules, correlation with specific chemical functionalities, etc.), especially in the molecular population of polycyclic aromatic hydrocarbons (PAHs). We describe these differences and discuss how they may be used to delineate the various interstellar processes that may have contributed to meteoritic D enrichments. We also briefly discuss how these processes may affect the isotopic distributions in C, 0, and N in the same compounds.

  13. Are there molecular signatures?

    SciTech Connect

    Bennett, W.P.

    1995-10-01

    This report describes molecular signatures and mutational spectrum analysis. The mutation spectrum is defined as the type and location of DNA base change. There are currently about five well documented cases. Mutations and radon-associated tumors are discussed.

  14. Meteor signature interpretation

    SciTech Connect

    Canavan, G.H.

    1997-01-01

    Meteor signatures contain information about the constituents of space debris and present potential false alarms to early warnings systems. Better models could both extract the maximum scientific information possible and reduce their danger. Accurate predictions can be produced by models of modest complexity, which can be inverted to predict the sizes, compositions, and trajectories of object from their signatures for most objects of interest and concern.

  15. UV signature mutations.

    PubMed

    Brash, Douglas E

    2015-01-01

    Sequencing complete tumor genomes and exomes has sparked the cancer field's interest in mutation signatures for identifying the tumor's carcinogen. This review and meta-analysis discusses signatures and their proper use. We first distinguish between a mutagen's canonical mutations—deviations from a random distribution of base changes to create a pattern typical of that mutagen—and the subset of signature mutations, which are unique to that mutagen and permit inference backward from mutations to mutagen. To verify UV signature mutations, we assembled literature datasets on cells exposed to UVC, UVB, UVA, or solar simulator light (SSL) and tested canonical UV mutation features as criteria for clustering datasets. A confirmed UV signature was: ≥60% of mutations are C→T at a dipyrimidine site, with ≥5% CC→TT. Other canonical features such as a bias for mutations on the nontranscribed strand or at the 3' pyrimidine had limited application. The most robust classifier combined these features with criteria for the rarity of non-UV canonical mutations. In addition, several signatures proposed for specific UV wavelengths were limited to specific genes or species; UV's nonsignature mutations may cause melanoma BRAF mutations; and the mutagen for sunlight-related skin neoplasms may vary between continents. PMID:25354245

  16. ERS-1 SAR data processing

    NASA Technical Reports Server (NTRS)

    Leung, K.; Bicknell, T.; Vines, K.

    1986-01-01

    To take full advantage of the synthetic aperature radar (SAR) to be flown on board the European Space Agency's Remote Sensing Satellite (ERS-1) (1989) and the Canadian Radarsat (1990), the implementation of a receiving station in Alaska is being studied to gather and process SAR data pertaining in particular to regions within the station's range of reception. The current SAR data processing requirement is estimated to be on the order of 5 minutes per day. The Interim Digital Sar Processor (IDP) which was under continual development through Seasat (1978) and SIR-B (1984) can process slightly more than 2 minutes of ERS-1 data per day. On the other hand, the Advanced Digital SAR Processore (ADSP), currently under development for the Shuttle Imaging Radar C (SIR-C, 1988) and the Venus Radar Mapper, (VMR, 1988), is capable of processing ERS-1 SAR data at a real time rate. To better suit the anticipated ERS-1 SAR data processing requirement, both a modified IDP and an ADSP derivative are being examined. For the modified IDP, a pipelined architecture is proposed for the mini-computer plus array processor arrangement to improve throughout. For the ADSP derivative, a simplified version is proposed to enhance ease of implementation and maintainability while maintaing real time throughput rates. These processing systems are discussed and evaluated.

  17. Invisibly Sanitizable Signature without Pairings

    NASA Astrophysics Data System (ADS)

    Yum, Dae Hyun; Lee, Pil Joong

    Sanitizable signatures allow sanitizers to delete some pre-determined parts of a signed document without invalidating the signature. While ordinary sanitizable signatures allow verifiers to know how many subdocuments have been sanitized, invisibly sanitizable signatures do not leave any clue to the sanitized subdocuments; verifiers do not know whether or not sanitizing has been performed. Previous invisibly sanitizable signature scheme was constructed based on aggregate signature with pairings. In this article, we present the first invisibly sanitizable signature without using pairings. Our proposed scheme is secure under the RSA assumption.

  18. Functional Role of Ribosomal Signatures

    PubMed Central

    Chen, Ke; Eargle, John; Sarkar, Krishnarjun; Gruebele, Martin; Luthey-Schulten, Zaida

    2010-01-01

    Although structure and sequence signatures in ribosomal RNA and proteins are defining characteristics of the three domains of life and instrumental in constructing the modern phylogeny, little is known about their functional roles in the ribosome. In this work, the largest coevolving RNA/protein signatures in the bacterial 30S ribosome are investigated both experimentally and computationally through all-atom molecular-dynamics simulations. The complex includes the N-terminal fragment of the ribosomal protein S4, which is a primary binding protein that initiates 30S small subunit assembly from the 5′ domain, and helix 16 (h16), which is part of the five-way junction in 16S rRNA. Our results show that the S4 N-terminus signature is intrinsically disordered in solution, whereas h16 is relatively stable by itself. The dynamic disordered property of the protein is exploited to couple the folding and binding process to the five-way junction, and the results provide insight into the mechanism for the early and fast binding of S4 in the assembly of the ribosomal small subunit. PMID:21156135

  19. Nonlinear control of magnetic signatures

    NASA Astrophysics Data System (ADS)

    Niemoczynski, Bogdan

    Magnetic properties of ferrite structures are known to cause fluctuations in Earth's magnetic field around the object. These fluctuations are known as the object's magnetic signature and are unique based on the object's geometry and material. It is a common practice to neutralize magnetic signatures periodically after certain time intervals, however there is a growing interest to develop real time degaussing systems for various applications. Development of real time degaussing system is a challenging problem because of magnetic hysteresis and difficulties in measurement or estimation of near-field flux data. The goal of this research is to develop a real time feedback control system that can be used to minimize magnetic signatures for ferrite structures. Experimental work on controlling the magnetic signature of a cylindrical steel shell structure with a magnetic disturbance provided evidence that the control process substantially increased the interior magnetic flux. This means near field estimation using interior sensor data is likely to be inaccurate. Follow up numerical work for rectangular and cylindrical cross sections investigated variations in shell wall flux density under a variety of ambient excitation and applied disturbances. Results showed magnetic disturbances could corrupt interior sensor data and magnetic shielding due to the shell walls makes the interior very sensitive to noise. The magnetic flux inside the shell wall showed little variation due to inner disturbances and its high base value makes it less susceptible to noise. This research proceeds to describe a nonlinear controller to use the shell wall data as an input. A nonlinear plant model of magnetics is developed using a constant tau to represent domain rotation lag and a gain function k to describe the magnetic hysteresis curve for the shell wall. The model is justified by producing hysteresis curves for multiple materials, matching experimental data using a particle swarm algorithm, and

  20. In-situ Condition Monitoring of Components in Small Modular Reactors Using Process and Electrical Signature Analysis. Final report, volume 1. Development of experimental flow control loop, data analysis and plant monitoring

    SciTech Connect

    Upadhyaya, Belle; Hines, J. Wesley; Damiano, Brian; Mehta, Chaitanya; Collins, Price; Lish, Matthew; Cady, Brian; Lollar, Victor; de Wet, Dane; Bayram, Duygu

    2015-12-15

    The research and development under this project was focused on the following three major objectives: Objective 1: Identification of critical in-vessel SMR components for remote monitoring and development of their low-order dynamic models, along with a simulation model of an integral pressurized water reactor (iPWR). Objective 2: Development of an experimental flow control loop with motor-driven valves and pumps, incorporating data acquisition and on-line monitoring interface. Objective 3: Development of stationary and transient signal processing methods for electrical signatures, machinery vibration, and for characterizing process variables for equipment monitoring. This objective includes the development of a data analysis toolbox. The following is a summary of the technical accomplishments under this project: - A detailed literature review of various SMR types and electrical signature analysis of motor-driven systems was completed. A bibliography of literature is provided at the end of this report. Assistance was provided by ORNL in identifying some key references. - A review of literature on pump-motor modeling and digital signal processing methods was performed. - An existing flow control loop was upgraded with new instrumentation, data acquisition hardware and software. The upgrading of the experimental loop included the installation of a new submersible pump driven by a three-phase induction motor. All the sensors were calibrated before full-scale experimental runs were performed. - MATLAB-Simulink model of a three-phase induction motor and pump system was completed. The model was used to simulate normal operation and fault conditions in the motor-pump system, and to identify changes in the electrical signatures. - A simulation model of an integral PWR (iPWR) was updated and the MATLAB-Simulink model was validated for known transients. The pump-motor model was interfaced with the iPWR model for testing the impact of primary flow perturbations (upsets) on

  1. Magma Differentiation Processes That Develop an "Enriched" Signature in the Izu Bonin Rear Arc: Evidence from Drilling at IODP Site U1437

    NASA Astrophysics Data System (ADS)

    Heywood, L. J.; DeBari, S. M.; Schindlbeck, J. C.; Escobar-Burciaga, R. D.

    2015-12-01

    The Izu Bonin rear arc represents a unique laboratory to study the development of continental crust precursors at an intraoceanic subduction zone., Volcanic output in the Izu Bonin rear arc is compositionally distinct from the Izu Bonin main volcanic front, with med- to high-K and LREE-enrichment similar to the average composition of the continental crust. Drilling at IODP Expedition 350 Site U1437 in the Izu Bonin rear arc obtained volcaniclastic material that was deposited from at least 13.5 Ma to present. IODP Expedition 350 represents the first drilling mission in the Izu Bonin rear arc region. This study presents fresh glass and mineral compositions (obtained via EMP and LA-ICP-MS) from unaltered tephra layers in mud/mudstone (Lithostratigraphic Unit I) and lapillistone (Lithostratigraphic Unit II) <4.5 Ma to examine the geochemical signature of Izu Bonin rear arc magmas. Unit II samples are coarse-grained tephras that are mainly rhyolitic in composition (72.1-77.5 wt. % SiO2, 3.2-3.9 wt. % K2O and average Mg# 24) and LREE-enriched. These rear-arc rhyolites have an average La/Sm of 2.6 with flat HREEs, average Th/La of 0.15, and Zr/Y of 4.86. Rear-arc rhyolite trace element signature is distinct from felsic eruptive products from the Izu Bonin main volcanic front, which have lower La/Sm and Th/La as well as significantly lower incompatible element concentrations. Rear arc rhyolites have similar trace element ratios to rhyolites from the adjacent but younger backarc knolls and actively-extending rift regions, but the latter is typified by lower K2O, as well as a smaller degree of enrichment in incompatible elements. Given these unique characteristics, we explore models for felsic magma formation and intracrustal differentiation in the Izu Bonin rear arc.

  2. Practical quantum digital signature

    NASA Astrophysics Data System (ADS)

    Yin, Hua-Lei; Fu, Yao; Chen, Zeng-Bing

    2016-03-01

    Guaranteeing nonrepudiation, unforgeability as well as transferability of a signature is one of the most vital safeguards in today's e-commerce era. Based on fundamental laws of quantum physics, quantum digital signature (QDS) aims to provide information-theoretic security for this cryptographic task. However, up to date, the previously proposed QDS protocols are impractical due to various challenging problems and most importantly, the requirement of authenticated (secure) quantum channels between participants. Here, we present the first quantum digital signature protocol that removes the assumption of authenticated quantum channels while remaining secure against the collective attacks. Besides, our QDS protocol can be practically implemented over more than 100 km under current mature technology as used in quantum key distribution.

  3. Uncertainty in hydrological signatures

    NASA Astrophysics Data System (ADS)

    McMillan, Hilary; Westerberg, Ida

    2015-04-01

    Information that summarises the hydrological behaviour or flow regime of a catchment is essential for comparing responses of different catchments to understand catchment organisation and similarity, and for many other modelling and water-management applications. Such information types derived as an index value from observed data are known as hydrological signatures, and can include descriptors of high flows (e.g. mean annual flood), low flows (e.g. mean annual low flow, recession shape), the flow variability, flow duration curve, and runoff ratio. Because the hydrological signatures are calculated from observed data such as rainfall and flow records, they are affected by uncertainty in those data. Subjective choices in the method used to calculate the signatures create a further source of uncertainty. Uncertainties in the signatures may affect our ability to compare different locations, to detect changes, or to compare future water resource management scenarios. The aim of this study was to contribute to the hydrological community's awareness and knowledge of data uncertainty in hydrological signatures, including typical sources, magnitude and methods for its assessment. We proposed a generally applicable method to calculate these uncertainties based on Monte Carlo sampling and demonstrated it for a variety of commonly used signatures. The study was made for two data rich catchments, the 50 km2 Mahurangi catchment in New Zealand and the 135 km2 Brue catchment in the UK. For rainfall data the uncertainty sources included point measurement uncertainty, the number of gauges used in calculation of the catchment spatial average, and uncertainties relating to lack of quality control. For flow data the uncertainty sources included uncertainties in stage/discharge measurement and in the approximation of the true stage-discharge relation by a rating curve. The resulting uncertainties were compared across the different signatures and catchments, to quantify uncertainty

  4. Current signature sensor

    NASA Technical Reports Server (NTRS)

    Perotti, Jose M. (Inventor); Lucena, Angel (Inventor); Ihlefeld, Curtis (Inventor); Burns, Bradley (Inventor); Bassignani, Karin E. (Inventor)

    2005-01-01

    A solenoid health monitoring system uses a signal conditioner and controller assembly in one embodiment that includes analog circuitry and a DSP controller. The analog circuitry provides signal conditioning to the low-level raw signal coming from a signal acquisition assembly. Software running in a DSP analyzes the incoming data (recorded current signature) and determines the state of the solenoid whether it is energized, de-energized, or in a transitioning state. In one embodiment, the software identifies key features in the current signature during the transition phase and is able to determine the health of the solenoid.

  5. Current Signature Sensor

    NASA Technical Reports Server (NTRS)

    Perotti, Jose M. (Inventor); Lucena, Angel (Inventor); Ihlefeld, Curtis (Inventor); Burns, Bradley (Inventor); Bassignani, Mario (Inventor); Bassignani, Karin E. (Inventor)

    2005-01-01

    A solenoid health monitoring system uses a signal conditioner and controller assembly in one embodiment that includes analog circuitry and a DSP controller. The analog circuitry provides signal conditioning to the low-level raw signal coming from a signal acquisition assembly. Software running in a DSP analyzes the incoming data (recorded current signature) and determines the state of the solenoid whether it is energized, de-energized, or in a transitioning state. In one embodiment, the software identifies key features in the current signature during the transition phase and is able to determine the health of the solenoid.

  6. Observational Signatures of Magnetic Reconnection

    NASA Technical Reports Server (NTRS)

    Savage, Sabrina

    2014-01-01

    Magnetic reconnection is often referred to as the primary source of energy release during solar flares. Directly observing reconnection occurring in the solar atmosphere, however, is not trivial considering that the scale size of the diffusion region is magnitudes smaller than the observational capabilities of current instrumentation, and coronal magnetic field measurements are not currently sufficient to capture the process. Therefore, predicting and studying observationally feasible signatures of the precursors and consequences of reconnection is necessary for guiding and verifying the simulations that dominate our understanding. I will present a set of such observations, particularly in connection with long-duration solar events, and compare them with recent simulations and theoretical predictions.

  7. Formation and Processing of Amorphous Silicates in Primitive Carbonaceous Chondrites and Cometary Dust

    NASA Technical Reports Server (NTRS)

    Keller, Lindsay P.; Messenger, S.

    2012-01-01

    Chondritic-porous interplanetary dust particles (CP IDPs) exhibit strongly heterogeneous and unequilibrated mineralogy at sub-micron scales, are enriched in carbon, nitrogen and volatile trace elements, and contain abundant presolar materials [1-4]. These observations suggest that CP IDPs have largely escaped the thermal processing and water-rock interactions that have severely modified or destroyed the original mineralogy of primitive meteorites. CP IDPs are believed to represent direct samples of the building blocks of the Solar System - a complex mixture of nebular and presolar materials largely unperturbed by secondary processing. The chemical and isotopic properties of CP IDPs and their atmospheric entry velocities are also consistent with cometary origins. GEMS (glass with embedded metal and sulfides) grains are a major silicate component of CP IDPs. GEMS grains are < 0.5 microns in diameter objects that consist of numerous 10 to 50 nm-sized Fe-Ni metal and Fe-Ni sulfide grains dispersed in a Mg-Si-Al-Fe amorphous silicate matrix [2, 5]. Based on their chemistry and isotopic compositions, most GEMS appear to be non-equilibrium condensates from the early solar nebula [2]. If GEMS grains are a common nebular product, then they should also be abundant in the matrices of the most physically primitive chondritic meteorites. Although amorphous silicates are common in the most primitive meteorites [6-9], their relationship to GEMS grains and the extent to which their compositions and microstructure have been affected by parent body processing (oxidation and aqueous alteration) is poorly constrained. Here we compare and contrast the chemical, microstructural and isotopic properties of amorphous silicates in primitive carbonaceous chondrites to GEMS grains in IDPs.

  8. A Signature Style

    ERIC Educational Resources Information Center

    Smiles, Robin V.

    2005-01-01

    This article discusses Dr. Amalia Amaki and her approach to art as her signature style by turning everyday items into fine art. Amaki is an assistant professor of art, art history, and Black American studies at the University of Delaware. She loves taking unexpected an object and redefining it in the context of art--like a button, a fan, a faded…

  9. Concentration and chiral signature of chlordane in soils and sediments of the Central Tibetan Plateau, China: Transformation in the surficial process.

    PubMed

    Yuan, Guo-Li; Wu, Ming-Zhe; Sun, Yong; Li, Jun; Han, Peng; Wang, Gen-Hou

    2015-11-01

    The fraction of trans-chlordane (TC) in chlordane was used to indicate racemic degradation while the enantiomer fractions (EFs) indicated enantioselective depletion. In 44 soils of the Central Tibetan Plateau, the fractions of TC ranged from 0.368 to 0.411. The EFs ranged from 0.174 to 0.696 for TC and from 0.483 to 0.672 for cis-chlordane (CC). (-) enantiomer excess (ee) was found to be 80.0% in the soils for TC and (+) ee was 86.5% for CC. The fraction of TC changed with the clay content while the EFs changed with the soil organic carbon. Meanwhile, the fractions of TC and the EFs were determined for the surficial sediments in Yamzhog Yumco Lake, which were compared with those in the soils at its catchment area. The composition and chiral signature of chlordane did not vary between soils and sediments. Our results will help to elucidate the transformation of chlordane in soils and in surficial transport. PMID:26204573

  10. Searching the Inclusive Lepton + Photon + Missing E(T) + b-quark Signature for Radiative Top Quark Decay and Non-Standard-Model Processes

    SciTech Connect

    Aaltonen, T.; Adelman, Jahred A.; Akimoto, T.; Alvarez Gonzalez, B.; Amerio, S.; Amidei, Dante E.; Anastassov, A.; Annovi, Alberto; Antos, Jaroslav; Apollinari, G.; Apresyan, A.; /Purdue U. /Waseda U.

    2009-06-01

    In a search for new phenomena in a signature suppressed in the standard model of elementary particles (SM), we compare the inclusive production of events containing a lepton ({ell}), a photon ({gamma}), significant transverse momentum imbalance (E{sub T}), and a jet identified as containing a b-quark, to SM predictions. The search uses data produced in proton-antiproton collisions at {radical}s = 1.96 TeV corresponding to 1.9 fb{sup -1} of integrated luminosity taken with the CDF detector at the Fermilab Tevatron. We find 28 {ell}{gamma}bE{sub T} events versus an expectation of 31.0{sub -3.5}{sup +4.1} events. If we further require events to contain at least three jets and large total transverse energy, simulations predict that the largest SM source is top-quark pair production with an additional radiated photon, t{bar t} + {gamma}. In the data we observe 16 t{bar t}{gamma} candidate events versus an expectation from non-top-quark SM sources of 11.2{sub -2.1}{sup +2.3}. Assuming the difference between the observed number and the predicted non-top-quark total is due to SM top quark production, we estimate the t{bar t} cross section to be 0.15 {+-} 0.08 pb.

  11. Terahertz signature characterization of bio-simulants

    NASA Astrophysics Data System (ADS)

    Majewski, Alexander J.; Miller, Peter; Abreu, Rene; Grotts, Jeffrey; Globus, Tatiana; Brown, Elliott

    2005-05-01

    Collaboration with the University of Virginia (UVa) and the University of California, Santa Barbara (UCSB) has resulted in the collection of signature data in the THz region of the spectrum for ovalbumin, Bacillus Subtilis (BG) and RNA from MS2 phage. Two independent experimental measurement systems were used to characterize the bio-simulants. Prior to our efforts, only a limited signature database existed. The goal was to evaluate a larger ensemble of biological agent simulants (BG, MS2 and ovalbumin) by measuring their THz absorption spectra. UCSB used a photomixer spectrometer and UVa a Fourier Transform spectrometer to measure absorption spectra. Each group used different sample preparation techniques and made multiple measurements to provide reliable statistics. Data processing culminated in applying proprietary algorithms to develop detection filters for each simulant. Through a covariance matrix approach, the detection filters extract signatures over regions with strong absorption and ignore regions with large signature variation (noise). The discrimination capability of these filters was also tested. The probability of detection and false alarm for each simulant was analyzed by each simulant specific filter. We analyzed a limited set of Bacillus thuringiensis (BT) data (a near neighbor to BG) and were capable of discriminating between BT and BG. The signal processing and filter construction demonstrates signature specificity and filter discrimination capabilities.

  12. Ecosystem engineers and geomorphological signatures in landscapes

    NASA Astrophysics Data System (ADS)

    Jones, Clive G.

    2012-07-01

    Biogeomorphologists study the roles of biota in landscape formation and decay. Ecologists interested in ecosystem engineering study environmental change caused by biota and the consequences for the engineer, other organisms, and ecological processes. The interface is geomorphological change, an interface both are aware of but study somewhat independently and differently. Interaction and integration among the two fields is the goal of this special issue. Here I take an ecological perspective of geomorphological change caused by ecosystem engineers in patches within landscapes that I hope can help facilitate this goal. I ask the following general questions: When will an ecosystem engineering species create a geomorphological signature in a landscape? What, in qualitative terms, is such a signature? How can the signature be estimated and how long will it last? What engineer attributes and ecological factors will determine signature change? What creates complications? How do the answers inform whether or not life leaves a geomorphological signature? To attempt answers, I develop a provisional, general theory of ecosystem engineering signatures that draws on and integrates a geomorphological foundation of balance between formation and decay; landscape patch dynamics; a general framework for ecosystem engineering; and empirical studies. I treat a landscape engineering signature as the balance of rates of formation (F) and rates of decay (D) across patches whose ratio value (F/D) can be transformed (> 1), intermediate (1) or untransformed (< 1). I suggest amenable systems for study. I describe how the signature can be estimated and evaluated for potential persistence, and how to identify when decay or engineer density and per capita engineering activity control the signature. I examine the influences on shifts from transformed to untransformed signatures, and vice versa, at constant and changing rates of decay. I show how the likelihood of signature shifts depends on: 1

  13. Genetic signatures of heroin addiction

    PubMed Central

    Chen, Shaw-Ji; Liao, Ding-Lieh; Shen, Tsu-Wang; Yang, Hsin-Chou; Chen, Kuang-Chi; Chen, Chia-Hsiang

    2016-01-01

    Abstract Heroin addiction is a complex psychiatric disorder with a chronic course and a high relapse rate, which results from the interaction between genetic and environmental factors. Heroin addiction has a substantial heritability in its etiology; hence, identification of individuals with a high genetic propensity to heroin addiction may help prevent the occurrence and relapse of heroin addiction and its complications. The study aimed to identify a small set of genetic signatures that may reliably predict the individuals with a high genetic propensity to heroin addiction. We first measured the transcript level of 13 genes (RASA1, PRKCB, PDK1, JUN, CEBPG, CD74, CEBPB, AUTS2, ENO2, IMPDH2, HAT1, MBD1, and RGS3) in lymphoblastoid cell lines in a sample of 124 male heroin addicts and 124 male control subjects using real-time quantitative PCR. Seven genes (PRKCB, PDK1, JUN, CEBPG, CEBPB, ENO2, and HAT1) showed significant differential expression between the 2 groups. Further analysis using 3 statistical methods including logistic regression analysis, support vector machine learning analysis, and a computer software BIASLESS revealed that a set of 4 genes (JUN, CEBPB, PRKCB, ENO2, or CEBPG) could predict the diagnosis of heroin addiction with the accuracy rate around 85% in our dataset. Our findings support the idea that it is possible to identify genetic signatures of heroin addiction using a small set of expressed genes. However, the study can only be considered as a proof-of-concept study. As the establishment of lymphoblastoid cell line is a laborious and lengthy process, it would be more practical in clinical settings to identify genetic signatures for heroin addiction directly from peripheral blood cells in the future study. PMID:27495086

  14. Genetic signatures of heroin addiction.

    PubMed

    Chen, Shaw-Ji; Liao, Ding-Lieh; Shen, Tsu-Wang; Yang, Hsin-Chou; Chen, Kuang-Chi; Chen, Chia-Hsiang

    2016-08-01

    Heroin addiction is a complex psychiatric disorder with a chronic course and a high relapse rate, which results from the interaction between genetic and environmental factors. Heroin addiction has a substantial heritability in its etiology; hence, identification of individuals with a high genetic propensity to heroin addiction may help prevent the occurrence and relapse of heroin addiction and its complications. The study aimed to identify a small set of genetic signatures that may reliably predict the individuals with a high genetic propensity to heroin addiction. We first measured the transcript level of 13 genes (RASA1, PRKCB, PDK1, JUN, CEBPG, CD74, CEBPB, AUTS2, ENO2, IMPDH2, HAT1, MBD1, and RGS3) in lymphoblastoid cell lines in a sample of 124 male heroin addicts and 124 male control subjects using real-time quantitative PCR. Seven genes (PRKCB, PDK1, JUN, CEBPG, CEBPB, ENO2, and HAT1) showed significant differential expression between the 2 groups. Further analysis using 3 statistical methods including logistic regression analysis, support vector machine learning analysis, and a computer software BIASLESS revealed that a set of 4 genes (JUN, CEBPB, PRKCB, ENO2, or CEBPG) could predict the diagnosis of heroin addiction with the accuracy rate around 85% in our dataset. Our findings support the idea that it is possible to identify genetic signatures of heroin addiction using a small set of expressed genes. However, the study can only be considered as a proof-of-concept study. As the establishment of lymphoblastoid cell line is a laborious and lengthy process, it would be more practical in clinical settings to identify genetic signatures for heroin addiction directly from peripheral blood cells in the future study. PMID:27495086

  15. Evidence for Changes in 81PIWild 2 Organic Matter Since Collection and Comparison of 82PIWild 2 and IDP Organic Matter to Access the Thermal Effects of Aerogel Capture

    NASA Technical Reports Server (NTRS)

    Wirick, S.; Flynn, G. J.; Keller, L.; Messenger, Nakamura; Sandford, S. A.; Zolensky, M. E.; Peltzer, C.; Jacobsen, C.

    2009-01-01

    NASA s Stardust spacecraft collected cometary material during its passage through the dust coma of comet 81P/Wild 2 on January 2nd, 2004 and delivered this material to Earth on January 15th 2006. The first fragment we analyzed during the preliminary examination was partially vaporized by the X-ray beam. The carbonaceous material that survived was re-analysis approx.2 months later and the carbon spectrum for this material had significantly changed from what we first observed.. We have observed similar changes to the carbonaceous matter in some interplanetary dust particles ( IDPs). Some of the 81P/Wild 2 organic matter volatilized upon impact with the aerogel as observed using IR spectroscopy where IR spectra were collected several mms away from sample tracks [1]. The time-temperature profile experienced by any particular 81P/Wild 2 grain during aerogel capture is not known, although Brownlee, et al. suggest that fine-grained materials, <1 micron in size, fragmented and then partially vaporized during collection, while particles much larger then 1 micron in size were captured intact [2]. Nearly all organic matter is subject to thermal alteration. To assess the heating and alteration experienced by the 81P/Wild 2 organic matter during capture we are comparing 81P/Wild2 organic matter with IDP organic matter where we have evidence of heating in the IDP [3,4].

  16. Wake Signature Detection

    NASA Astrophysics Data System (ADS)

    Spedding, Geoffrey R.

    2014-01-01

    An accumulated body of quantitative evidence shows that bluff-body wakes in stably stratified environments have an unusual degree of coherence and organization, so characteristic geometries such as arrays of alternating-signed vortices have very long lifetimes, as measured in units of buoyancy timescales, or in the downstream distance scaled by a body length. The combination of pattern geometry and persistence renders the detection of these wakes possible in principle. It now appears that identifiable signatures can be found from many disparate sources: Islands, fish, and plankton all have been noted to generate features that can be detected by climate modelers, hopeful navigators in open oceans, or hungry predators. The various types of wakes are reviewed with notes on why their signatures are important and to whom. A general theory of wake pattern formation is lacking and would have to span many orders of magnitude in Reynolds number.

  17. Fluorescent taggants with temporally coded signatures.

    PubMed

    Wang, Siyang; Vyas, Raul; Dwyer, Chris

    2016-07-11

    In this paper, resonance energy transfer (RET) networks between chromophores are used to implement fluorescent taggants with temporally coded signatures. Because the temporal signature of such a fluorescent taggant is a phase-type distribution defined by the geometry of its RET network, the taggant design is not constrained by resolvable dyes and has a significantly larger coding capacity than spectrally or lifetime coded fluorescent taggants. Meanwhile, the detection process becomes highly efficient when the signatures are coded in the time domain. The taggant identification method is based on the multinomial distribution of detected photons and Maximum Likelihood Estimation, which guarantees high accuracy even with only a few hundred photons and also applies to a mixture of taggants in multiplex detection. Therefore, these temporally coded fluorescent taggants have great potential for both in situ and Lidar applications. PMID:27410827

  18. U.S. Army Research Laboratory (ARL) multimodal signatures database

    NASA Astrophysics Data System (ADS)

    Bennett, Kelly

    2008-04-01

    The U.S. Army Research Laboratory (ARL) Multimodal Signatures Database (MMSDB) is a centralized collection of sensor data of various modalities that are co-located and co-registered. The signatures include ground and air vehicles, personnel, mortar, artillery, small arms gunfire from potential sniper weapons, explosives, and many other high value targets. This data is made available to Department of Defense (DoD) and DoD contractors, Intel agencies, other government agencies (OGA), and academia for use in developing target detection, tracking, and classification algorithms and systems to protect our Soldiers. A platform independent Web interface disseminates the signatures to researchers and engineers within the scientific community. Hierarchical Data Format 5 (HDF5) signature models provide an excellent solution for the sharing of complex multimodal signature data for algorithmic development and database requirements. Many open source tools for viewing and plotting HDF5 signatures are available over the Web. Seamless integration of HDF5 signatures is possible in both proprietary computational environments, such as MATLAB, and Free and Open Source Software (FOSS) computational environments, such as Octave and Python, for performing signal processing, analysis, and algorithm development. Future developments include extending the Web interface into a portal system for accessing ARL algorithms and signatures, High Performance Computing (HPC) resources, and integrating existing database and signature architectures into sensor networking environments.

  19. Association Between a Prognostic Gene Signature and Functional Gene Sets

    PubMed Central

    Hummel, Manuela; Metzeler, Klaus H.; Buske, Christian; Bohlander, Stefan K.; Mansmann, Ulrich

    2008-01-01

    Background The development of expression-based gene signatures for predicting prognosis or class membership is a popular and challenging task. Besides their stringent validation, signatures need a functional interpretation and must be placed in a biological context. Popular tools such as Gene Set Enrichment have drawbacks because they are restricted to annotated genes and are unable to capture the information hidden in the signature’s non-annotated genes. Methodology We propose concepts to relate a signature with functional gene sets like pathways or Gene Ontology categories. The connection between single signature genes and a specific pathway is explored by hierarchical variable selection and gene association networks. The risk score derived from an individual patient’s signature is related to expression patterns of pathways and Gene Ontology categories. Global tests are useful for these tasks, and they adjust for other factors. GlobalAncova is used to explore the effect on gene expression in specific functional groups from the interaction of the score and selected mutations in the patient’s genome. Results We apply the proposed methods to an expression data set and a corresponding gene signature for predicting survival in Acute Myeloid Leukemia (AML). The example demonstrates strong relations between the signature and cancer-related pathways. The signature-based risk score was found to be associated with development-related biological processes. Conclusions Many authors interpret the functional aspects of a gene signature by linking signature genes to pathways or relevant functional gene groups. The method of gene set enrichment is preferred to annotating signature genes to specific Gene Ontology categories. The strategies proposed in this paper go beyond the restriction of annotation and deepen the insights into the biological mechanisms reflected in the information given by a signature. PMID:19812786

  20. Temporal Cusp Ion Signatures and Magnetopause Reconnection during Northward IMF

    NASA Astrophysics Data System (ADS)

    Connor, H. K.; Sibeck, D. G.; Raeder, J.; Trattner, K. J.

    2015-12-01

    Dispersed ion signatures observed in the magnetospheric cusps have been used to understand the locations and properties of magnetopause reconnection. Whether a cusp structure is spatial or temporal is an important question because these structures reveal the spatial and temporal nature of magnetopause reconnection. We study temporal cusp ion signatures and their relation to the magnetopause processes during northward IMF using the Open Global Geospace Circulation Model (OpenGGCM) and the Liouville Theorem Particle Tracer (LTPT). OpenGGCM produces dayside reconnection within the framework of resistive MHD, while the LTPT calculates cusp ion signatures caused by the simulated reconnection. Our model produces temporal cusp ion dispersions with ion energies that increase with decreasing latitude during northward IMF, although these signatures are commonly associated with subsolar reconnection during southward IMF. We investigate which magnetopause process is responsible for the temporal cusp signatures.

  1. The Effects of Differentiated Instruction on the Literacy Process of Learners with Interrupted Schooling

    ERIC Educational Resources Information Center

    Niño Santisteban, Liliana

    2014-01-01

    This research study analyzes the literacy and foreign langauge processes of learners in the "Procesos Básicos" Program. The participants were 15 Spanish-speaking children and young adolescents, whose highest level of education was first grade. Eight of the 15 children were Internally Displaced Persons (IDPs), and the others were affected…

  2. Image processing and products for the Magellan mission to Venus

    NASA Technical Reports Server (NTRS)

    Clark, Jerry; Alexander, Doug; Andres, Paul; Lewicki, Scott; Mcauley, Myche

    1992-01-01

    The Magellan mission to Venus is providing planetary scientists with massive amounts of new data about the surface geology of Venus. Digital image processing is an integral part of the ground data system that provides data products to the investigators. The mosaicking of synthetic aperture radar (SAR) image data from the spacecraft is being performed at JPL's Multimission Image Processing Laboratory (MIPL). MIPL hosts and supports the Image Data Processing Subsystem (IDPS), which was developed in a VAXcluster environment of hardware and software that includes optical disk jukeboxes and the TAE-VICAR (Transportable Applications Executive-Video Image Communication and Retrieval) system. The IDPS is being used by processing analysts of the Image Data Processing Team to produce the Magellan image data products. Various aspects of the image processing procedure are discussed.

  3. Signature CERN-URSS

    ScienceCinema

    None

    2011-04-25

    Le DG W.Jentschke souhaite la bienvenue à l'assemblée et aux invités pour la signature du protocole entre le Cern et l'URSS qui est un événement important. C'est en 1955 que 55 visiteurs soviétiques ont visité le Cern pour la première fois. Le premier DG au Cern, F.Bloch, et Mons.Amaldi sont aussi présents. Tandis que le discours anglais de W.Jentschke est traduit en russe, le discours russe de Mons.Morozov est traduit en anglais.

  4. Holographic signatures of cosmological singularities.

    PubMed

    Engelhardt, Netta; Hertog, Thomas; Horowitz, Gary T

    2014-09-19

    To gain insight into the quantum nature of cosmological singularities, we study anisotropic Kasner solutions in gauge-gravity duality. The dual description of the bulk evolution towards the singularity involves N=4 super Yang-Mills theory on the expanding branch of deformed de Sitter space and is well defined. We compute two-point correlators of Yang-Mills operators of large dimensions using spacelike geodesics anchored on the boundary. The correlators show a strong signature of the singularity around horizon scales and decay at large boundary separation at different rates in different directions. More generally, the boundary evolution exhibits a process of particle creation similar to that in inflation. This leads us to conjecture that information on the quantum nature of cosmological singularities is encoded in long-wavelength features of the boundary wave function. PMID:25279620

  5. Clustering signatures classify directed networks

    NASA Astrophysics Data System (ADS)

    Ahnert, S. E.; Fink, T. M. A.

    2008-09-01

    We use a clustering signature, based on a recently introduced generalization of the clustering coefficient to directed networks, to analyze 16 directed real-world networks of five different types: social networks, genetic transcription networks, word adjacency networks, food webs, and electric circuits. We show that these five classes of networks are cleanly separated in the space of clustering signatures due to the statistical properties of their local neighborhoods, demonstrating the usefulness of clustering signatures as a classifier of directed networks.

  6. Advanced spectral signature discrimination algorithm

    NASA Astrophysics Data System (ADS)

    Chakravarty, Sumit; Cao, Wenjie; Samat, Alim

    2013-05-01

    This paper presents a novel approach to the task of hyperspectral signature analysis. Hyperspectral signature analysis has been studied a lot in literature and there has been a lot of different algorithms developed which endeavors to discriminate between hyperspectral signatures. There are many approaches for performing the task of hyperspectral signature analysis. Binary coding approaches like SPAM and SFBC use basic statistical thresholding operations to binarize a signature which are then compared using Hamming distance. This framework has been extended to techniques like SDFC wherein a set of primate structures are used to characterize local variations in a signature together with the overall statistical measures like mean. As we see such structures harness only local variations and do not exploit any covariation of spectrally distinct parts of the signature. The approach of this research is to harvest such information by the use of a technique similar to circular convolution. In the approach we consider the signature as cyclic by appending the two ends of it. We then create two copies of the spectral signature. These three signatures can be placed next to each other like the rotating discs of a combination lock. We then find local structures at different circular shifts between the three cyclic spectral signatures. Texture features like in SDFC can be used to study the local structural variation for each circular shift. We can then create different measure by creating histogram from the shifts and thereafter using different techniques for information extraction from the histograms. Depending on the technique used different variant of the proposed algorithm are obtained. Experiments using the proposed technique show the viability of the proposed methods and their performances as compared to current binary signature coding techniques.

  7. Multimodal signature modeling of humans

    NASA Astrophysics Data System (ADS)

    Cathcart, J. Michael; Kocher, Brian; Prussing, Keith; Lane, Sarah; Thomas, Alan

    2010-04-01

    Georgia Tech been investigating method for the detection of covert personnel in traditionally difficult environments (e.g., urban, caves). This program focuses on a detailed phenomenological analysis of human physiology and signatures with the subsequent identification and characterization of potential observables. Both aspects are needed to support the development of personnel detection and tracking algorithms. The difficult nature of these personnel-related problems dictates a multimodal sensing approach. Human signature data of sufficient and accurate quality and quantity do not exist, thus the development of an accurate signature model for a human is needed. This model should also simulate various human activities to allow motion-based observables to be exploited. This paper will describe a multimodal signature modeling approach that incorporates human physiological aspects, thermoregulation, and dynamics into the signature calculation. This approach permits both passive and active signatures to be modeled. The focus of the current effort involved the computation of signatures in urban environments. This paper will discuss the development of a human motion model for use in simulating both electro-optical signatures and radar-based signatures. Video sequences of humans in a simulated urban environment will also be presented; results using these sequences for personnel tracking will be presented.

  8. Contrasting isotopic signatures between anthropogenic and geogenic Zn and evidence for post-depositional fractionation processes in smelter-impacted soils from Northern France

    NASA Astrophysics Data System (ADS)

    Juillot, Farid; Maréchal, Chloe; Morin, Guillaume; Jouvin, Delphine; Cacaly, Sylvain; Telouk, Philipe; Benedetti, Marc F.; Ildefonse, Philippe; Sutton, Steve; Guyot, François; Brown, Gordon E., Jr.

    2011-05-01

    Zinc isotopes have been studied along two smelter-impacted soil profiles sampled near one of the largest Pb and Zn processing plants in Europe located in northern France, about 50 km south of Lille. Mean δ 66Zn values along these two soil profiles range from +0.22 ± 0.17‰ (2 σ) to +0.34 ± 0.17‰ (2 σ) at the lowest horizons and from +0.38 ± 0.45‰ (2 σ) to +0.76 ± 0.14‰ (2 σ) near the surface. The δ 66Zn values in the lowest horizons of the soils are interpreted as being representative of the local geochemical background (mean value +0.31 ± 0.38‰), whereas heavier δ 66Zn values near the surface of the two soils are related to anthropogenic Zn. This anthropogenic Zn occurs in the form of franklinite (ZnFe 2O 4)-bearing slag grains originating from processing wastes at the smelter site and exhibiting δ 66Zn values of +0.81 ± 0.20‰ (2 σ). The presence of franklinite is indicated by EXAFS analysis of the topsoil samples from both soil profiles as well as by micro-XANES analysis of the surface horizon of a third smelter-impacted soil from a distant site. These results indicate that naturally occurring Zn and smelter-derived Zn exhibit significantly different δ 66Zn values, which suggests that zinc isotopes can be used to distinguish between geogenic and anthropogenic sources of Zn in smelter-impacted soils. In addition to a possible influence of additional past sources of light Zn (likely Zn-sulfides and Zn-sulfates directly emitted by the smelter), the light δ 66Zn values in the surface horizons compared to smelter-derived slag materials are interpreted as resulting mainly from fractionation processes associated with biotic and/or abiotic pedological processes (Zn-bearing mineral precipitation, Zn complexation by organic matter, and plant uptake of Zn). This conclusion emphasizes the need for additional Zn isotopic studies before being able to use Zn isotopes to trace sources and pathways of this element in surface environments.

  9. Signature-extendable technology - Global space-based crop recognition

    NASA Technical Reports Server (NTRS)

    Hall, Forrest G.; Badhwar, Gautam D.

    1987-01-01

    The use of signature-extendable technology to improve the efficiency of machine processing of remotely sensed data is examined. Temporal profile technology is employed to automatically recognize crops; the technique uses the Kauth and Thomas (1976) transform of Landsat, multidata, and parameters derived from a model of each crop's greenness-time trajectory. The basic characteristics of temporal profile technology and the U.S. based labeling algorithm are described. Consideration is given to signature extension, signature-extendable spaces, and signature-extendable features. The greenness and brightness parameters used in temporal profile technology are derived. The signature extendability of the parameters is evaluated by applying them to the analysis of corn and soybean crops in the U.S. and Argentina. It is noted that the technique is an affordable and efficient method for deriving data on crops on a global basis.

  10. EUROPIUM s-PROCESS SIGNATURE AT CLOSE-TO-SOLAR METALLICITY IN STARDUST SiC GRAINS FROM ASYMPTOTIC GIANT BRANCH STARS

    SciTech Connect

    Avila, Janaina N.; Ireland, Trevor R.; Holden, Peter; Lugaro, Maria; Gyngard, Frank; Zinner, Ernst; Cristallo, Sergio; Rauscher, Thomas

    2013-05-01

    Individual mainstream stardust silicon carbide (SiC) grains and a SiC-enriched bulk sample from the Murchison carbonaceous meteorite have been analyzed by the Sensitive High Resolution Ion Microprobe-Reverse Geometry for Eu isotopes. The mainstream grains are believed to have condensed in the outflows of {approx}1.5-3 M{sub Sun} carbon-rich asymptotic giant branch (AGB) stars with close-to-solar metallicity. The {sup 151}Eu fractions [fr({sup 151}Eu) = {sup 151}Eu/({sup 151}Eu+{sup 153}Eu)] derived from our measurements are compared with previous astronomical observations of carbon-enhanced metal-poor stars enriched in elements made by slow neutron captures (the s-process). Despite the difference in metallicity between the parent stars of the grains and the metal-poor stars, the fr({sup 151}Eu) values derived from our measurements agree well with fr({sup 151}Eu) values derived from astronomical observations. We have also compared the SiC data with theoretical predictions of the evolution of Eu isotopic ratios in the envelope of AGB stars. Because of the low Eu abundances in the SiC grains, the fr({sup 151}Eu) values derived from our measurements show large uncertainties, in most cases being larger than the difference between solar and predicted fr({sup 151}Eu) values. The SiC aggregate yields a fr({sup 151}Eu) value within the range observed in the single grains and provides a more precise result (fr({sup 151}Eu) = 0.54 {+-} 0.03, 95% conf.), but is approximately 12% higher than current s-process predictions. The AGB models can match the SiC data if we use an improved formalism to evaluate the contribution of excited nuclear states in the calculation of the {sup 151}Sm(n, {gamma}) stellar reaction rate.

  11. Irma multisensor predictive signature model

    NASA Astrophysics Data System (ADS)

    Watson, John S.; Flynn, David S.; Wellfare, Michael R.; Richards, Mike; Prestwood, Lee

    1995-06-01

    The Irma synthetic signature model was one of the first high resolution synthetic infrared (IR) target and background signature models to be developed for tactical air-to-surface weapon scenarios. Originally developed in 1980 by the Armament Directorate of the Air Force Wright Laboratory (WL/MN), the Irma model was used exclusively to generate IR scenes for smart weapons research and development. In 1988, a number of significant upgrades to Irma were initiated including the addition of a laser channel. This two channel version, Irma 3.0, was released to the user community in 1990. In 1992, an improved scene generator was incorporated into the Irma model which supported correlated frame-to-frame imagery. This and other improvements were released in Irma 2.2. Recently, Irma 3.2, a passive IR/millimeter wave (MMW) code, was completed. Currently, upgrades are underway to include an active MMW channel. Designated Irma 4.0, this code will serve as a cornerstone of sensor fusion research in the laboratory from 6.1 concept development to 6.3 technology demonstration programs for precision guided munitions. Several significant milestones have been reached in this development process and are demonstrated. The Irma 4.0 software design has been developed and interim results are available. Irma is being developed to facilitate multi-sensor smart weapons research and development. It is currently in distribution to over 80 agencies within the U.S. Air Force, U.S. Army, U.S. Navy, ARPA, NASA, Department of Transportation, academia, and industry.

  12. Neural signatures of autism

    PubMed Central

    Kaiser, Martha D.; Hudac, Caitlin M.; Shultz, Sarah; Lee, Su Mei; Cheung, Celeste; Berken, Allison M.; Deen, Ben; Pitskel, Naomi B.; Sugrue, Daniel R.; Voos, Avery C.; Saulnier, Celine A.; Ventola, Pamela; Wolf, Julie M.; Klin, Ami; Vander Wyk, Brent C.; Pelphrey, Kevin A.

    2010-01-01

    Functional magnetic resonance imaging of brain responses to biological motion in children with autism spectrum disorder (ASD), unaffected siblings (US) of children with ASD, and typically developing (TD) children has revealed three types of neural signatures: (i) state activity, related to the state of having ASD that characterizes the nature of disruption in brain circuitry; (ii) trait activity, reflecting shared areas of dysfunction in US and children with ASD, thereby providing a promising neuroendophenotype to facilitate efforts to bridge genomic complexity and disorder heterogeneity; and (iii) compensatory activity, unique to US, suggesting a neural system–level mechanism by which US might compensate for an increased genetic risk for developing ASD. The distinct brain responses to biological motion exhibited by TD children and US are striking given the identical behavioral profile of these two groups. These findings offer far-reaching implications for our understanding of the neural systems underlying autism. PMID:21078973

  13. Signatures of Reputation

    NASA Astrophysics Data System (ADS)

    Bethencourt, John; Shi, Elaine; Song, Dawn

    Reputation systems have become an increasingly important tool for highlighting quality information and filtering spam within online forums. However, the dependence of a user's reputation on their history of activities seems to preclude any possibility of anonymity. We show that useful reputation information can, in fact, coexist with strong privacy guarantees. We introduce and formalize a novel cryptographic primitive we call signatures of reputation which supports monotonic measures of reputation in a completely anonymous setting. In our system, a user can express trust in others by voting for them, collect votes to build up her own reputation, and attach a proof of her reputation to any data she publishes, all while maintaining the unlinkability of her actions.

  14. Signatures of aging revisited

    SciTech Connect

    Drell, S.; Jeanloz, R.; Cornwall, J.; Dyson, F.; Eardley, D.

    1998-03-18

    This study is a follow-on to the review made by JASON during its 1997 Summer Study of what is known about the aging of critical constituents, particularly the high explosives, metals (Pu, U), and polymers in the enduring stockpile. The JASON report (JSR-97-320) that summarized the findings was based on briefings by the three weapons labs (LANL, LLNL, SNL). They presented excellent technical analyses covering a broad range of scientific and engineering problems pertaining to determining signatures of aging. But the report also noted: `Missing, however, from the briefings and the written documents made available to us by the labs and DOE, was evidence of an adequately sharp focus and high priorities on a number of essential near-term needs of maintaining weapons in the stockpile.

  15. Multisensors signature prediction workbench

    NASA Astrophysics Data System (ADS)

    Latger, Jean; Cathala, Thierry

    2015-10-01

    Guidance of weapon systems relies on sensors to analyze targets signature. Defense weapon systems also need to detect then identify threats also using sensors. The sensors performance is very dependent on conditions e.g. time of day, atmospheric propagation, background ... Visible camera are very efficient for diurnal fine weather conditions, long wave infrared sensors for night vision, radar systems very efficient for seeing through atmosphere and/or foliage ... Besides, multi sensors systems, combining several collocated sensors with associated algorithms of fusion, provide better efficiency (typically for Enhanced Vision Systems). But these sophisticated systems are all the more difficult to conceive, assess and qualify. In that frame, multi sensors simulation is highly required. This paper focuses on multi sensors simulation tools. A first part makes a state of the Art of such simulation workbenches with a special focus on SE-Workbench. SEWorkbench is described with regards to infrared/EO sensors, millimeter waves sensors, active EO sensors and GNSS sensors. Then a general overview of simulation of targets and backgrounds signature objectives is presented, depending on the type of simulation required (parametric studies, open loop simulation, closed loop simulation, hybridization of SW simulation and HW ...). After the objective review, the paper presents some basic requirements for simulation implementation such as the deterministic behavior of simulation, mandatory to repeat it many times for parametric studies... Several technical topics are then discussed, such as the rendering technique (ray tracing vs. rasterization), the implementation (CPU vs. GP GPU) and the tradeoff between physical accuracy and performance of computation. Examples of results using SE-Workbench are showed and commented.

  16. Signatures of dark matter

    NASA Astrophysics Data System (ADS)

    Baltz, Edward Anthony

    It is well known that most of the mass in the universe remains unobserved save for its gravitational effect on luminous matter. The nature of this ``dark matter'' remains a mystery. From measurements of the primordial deuterium abundance, the theory of big bang nucleosynthesis predicts that there are not enough baryons to account for the amount of dark matter observed, thus the missing mass must take an exotic form. Several promising candidates have been proposed. In this work I will describe my research along two main lines of inquiry into the dark matter puzzle. The first possibility is that the dark matter is exotic massive particles, such as those predicted by supersymmetric extensions to the standard model of particle physics. Such particles are generically called WIMPs, for weakly interacting massive particles. Focusing on the so-called neutralino in supersymmetric models, I discuss the possible signatures of such particles, including their direct detection via nuclear recoil experiments and their indirect detection via annihilations in the halos of galaxies, producing high energy antiprotons, positrons and gamma rays. I also discuss signatures of the possible slow decays of such particles. The second possibility is that there is a population of black holes formed in the early universe. Any dark objects in galactic halos, black holes included, are called MACHOs, for massive compact halo objects. Such objects can be detected by their gravitational microlensing effects. Several possibilities for sources of baryonic dark matter are also interesting for gravitational microlensing. These include brown dwarf stars and old, cool white dwarf stars. I discuss the theory of gravitational microlensing, focusing on the technique of pixel microlensing. I make predictions for several planned microlensing experiments with ground based and space based telescopes. Furthermore, I discuss binary lenses in the context of pixel microlensing. Finally, I develop a new technique for

  17. Signatures of AGN feedback

    NASA Astrophysics Data System (ADS)

    Wylezalek, D.; Zakamska, N.

    2016-06-01

    Feedback from active galactic nuclei (AGN) is widely considered to be the main driver in regulating the growth of massive galaxies. It operates by either heating or driving the gas that would otherwise be available for star formation out of the galaxy, preventing further increase in stellar mass. Observational proof for this scenario has, however, been hard to come by. We have assembled a large sample of 133 radio-quiet type-2 and red AGN at 0.1signatures are hosted in galaxies that are more `quenched' considering their stellar mass than galaxies with weaker outflow signatures. This correlation is only seen in AGN host galaxies with SFR >100 M_{⊙} yr^{-1} where presumably the coupling of the AGN-driven wind to the gas is strongest. This observation is consistent with the AGN having a net suppression, or `negative' impact, through feedback on the galaxies' star formation history.

  18. An Arbitrated Quantum Signature with Bell States

    NASA Astrophysics Data System (ADS)

    Liu, Feng; Qin, Su-Juan; Huang, Wei

    2014-05-01

    Entanglement is the main resource in quantum communication. The main aims of the arbitrated quantum signature (AQS) scheme are to present an application of the entanglement in cryptology and to prove the possibility of the quantum signature. More specifically, the main function of quantum entangled states in the existing AQS schemes is to assist the signatory to transfer quantum states to the receiver. However, teleportation and the Leung quantum one-time pad (L-QOTP) algorithm are not enough to design a secure AQS scheme. For example, Pauli operations commute or anticommute with each other, which makes the implementation of attacks easily from the aspects of forgery and disavowal. To conquer this shortcoming, we construct an improved AQS scheme using a new QOTP algorithm. This scheme has three advantages: it randomly uses the Hadamard operation in the new QOTP to resist attacks by using the anticommutativity of nontrivial Pauli operators and it preserves almost all merits in the existing AQS schemes; even in the process of handling disputes, no party has chance to change the message and its signature without being discovered; the receiver can verify the integrity of the signature and discover the disavow of the signatory even in the last step of verification.

  19. Improving interpretation of geoelectrical signatures arising from biomineralization process in porous media: Low-frequency dielectric spectroscopy measurements on Desulfovibrio vulgaris cell suspensions

    NASA Astrophysics Data System (ADS)

    Zhang, C.; Prodan, C.; Slater, L. D.; Bot, C.; Ntarlagiannis, D.

    2009-12-01

    dilute suspension of polarizable spheres with the polarization attributed to the surface charge on the cell walls. Our results provide insights into the likely contribution of the cells themselves to biogeophysical signals observed during biomineralization processes.

  20. New online signature acquisition system

    NASA Astrophysics Data System (ADS)

    Oulefki, Adel; Mostefai, Messaoud; Abbadi, Belkacem; Djebrani, Samira; Bouziane, Abderraouf; Chahir, Youssef

    2013-01-01

    We present a nonconstraining and low-cost online signature acquisition system that has been developed to enhance the performances of an existing multimodal biometric authentication system (based initially on both voice and image modalities). A laboratory prototype has been developed and validated for an online signature acquisition.

  1. (abstract) Topographic Signatures in Geology

    NASA Technical Reports Server (NTRS)

    Farr, Tom G.; Evans, Diane L.

    1996-01-01

    Topographic information is required for many Earth Science investigations. For example, topography is an important element in regional and global geomorphic studies because it reflects the interplay between the climate-driven processes of erosion and the tectonic processes of uplift. A number of techniques have been developed to analyze digital topographic data, including Fourier texture analysis. A Fourier transform of the topography of an area allows the spatial frequency content of the topography to be analyzed. Band-pass filtering of the transform produces images representing the amplitude of different spatial wavelengths. These are then used in a multi-band classification to map units based on their spatial frequency content. The results using a radar image instead of digital topography showed good correspondence to a geologic map, however brightness variations in the image unrelated to topography caused errors. An additional benefit to the use of Fourier band-pass images for the classification is that the textural signatures of the units are quantative measures of the spatial characteristics of the units that may be used to map similar units in similar environments.

  2. On the signature of LINCOS

    NASA Astrophysics Data System (ADS)

    Ollongren, Alexander

    2010-12-01

    Suppose the international SETI effort yields the discovery of some signal of evidently non-natural origin. Could it contain linguistic information formulated in some kind of Lingua Cosmica? One way to get insight into this matter is to consider what specific (bio) linguistic signature( s) could be attached to a cosmic language for interstellar communication—designed by humans or an alien society having reached a level of intelligence (and technology) comparable to or surpassing ours. For this purpose, we consider in the present paper the logico-linguistic system LINCOS for ( A)CETI, developed during a number of years by the author in several papers and a monograph [1]. The system has a two-fold signature, which distinguishes it significantly from natural languages. In fact abstract and concrete signatures can be distinguished. That an abstract kind occurs is due to the manner in which abstractions of reality are represented in LINCOS-texts. They can take compound forms because the system is multi-expressive—partly due to the availability of inductive (recursive) entities. On the other hand, the concrete signature of LINCOS is related to the distribution of delimiters and predefined tokens in texts. Assigning measures to concrete signatures will be discussed elsewhere. The present contribution concentrates on the abstract signature of the language. At the same time, it is realized that an alien Lingua Cosmica might, but not necessarily needs to have this kind of signatures.

  3. UHECR: Signatures and models

    NASA Astrophysics Data System (ADS)

    Berezinsky, V.

    2013-06-01

    The signatures of Ultra High Energy (E ≳ 1 EeV) proton propagation through CMB radiation are pair-production dip and GZK cutoff. The visible characteristics of these two spectral features are ankle, which is intrinsic part of the dip, beginning of GZK cutoff in the differential spectrum and E1/2 in integral spectrum. Measured by HiRes and Telescope Array (TA) these characteristics agree with theoretical predictions. However, directly measured mass composition remains a puzzle. While HiRes and TA detectors observe the proton-dominated mass composition, the data of Auger detector strongly evidence for nuclei mass composition becoming progressively heavier at energy higher than 4 EeV and reaching Iron at energy about 35 EeV. The models based on the Auger and HiRes/TA data are considered independently and classified using the transition from galactic to extragalactic cosmic rays. The ankle cannot provide this transition. since data of all three detector at energy (1-3) EeV agree with pure proton composition (or at least not heavier than Helium). If produced in Galaxy these particles result in too high anisotropy. This argument excludes or strongly disfavours all ankle models with ankle energy Ea > 3 EeV. The calculation of elongation curves, Xmax(E), for different ankle models strengthens further this conclusion. Status of other models, the dip, mixed composition and Auger based models are discussed.

  4. Infrasound Rocket Signatures

    NASA Astrophysics Data System (ADS)

    Olson, J.

    2012-09-01

    This presentation reviews the work performed by our research group at the Geophysical Institute as we have applied the tools of infrasound research to rocket studies. This report represents one aspect of the effort associated with work done for the National Consortium for MASINT Research (NCMR) program operated by the National MASINT Office (NMO) of the Defense Intelligence Agency (DIA). Infrasound, the study of acoustic signals and their propagation in a frequency band below 15 Hz, enables an investigator to collect and diagnose acoustic signals from distant sources. Absorption of acoustic energy in the atmosphere decreases as the frequency is reduced. In the infrasound band signals can propagate hundreds and thousands of kilometers with little degradation. We will present an overview of signatures from rockets ranging from small sounding rockets such as the Black Brandt and Orion series to larger rockets such as Delta 2,4 and Atlas V. Analysis of the ignition transients provides information that can uniquely identify the motor type. After the rocket ascends infrasound signals can be used to characterize the rocket and identify the various events that take place along a trajectory such as staging and maneuvering. We have also collected information on atmospheric shocks and sonic booms from the passage of supersonic vehicles such as the shuttle. This review is intended to show the richness of the unique signal set that occurs in the low-frequency infrasound band.

  5. Statistical clumped isotope signatures

    PubMed Central

    Röckmann, T.; Popa, M. E.; Krol, M. C.; Hofmann, M. E. G.

    2016-01-01

    High precision measurements of molecules containing more than one heavy isotope may provide novel constraints on element cycles in nature. These so-called clumped isotope signatures are reported relative to the random (stochastic) distribution of heavy isotopes over all available isotopocules of a molecule, which is the conventional reference. When multiple indistinguishable atoms of the same element are present in a molecule, this reference is calculated from the bulk (≈average) isotopic composition of the involved atoms. We show here that this referencing convention leads to apparent negative clumped isotope anomalies (anti-clumping) when the indistinguishable atoms originate from isotopically different populations. Such statistical clumped isotope anomalies must occur in any system where two or more indistinguishable atoms of the same element, but with different isotopic composition, combine in a molecule. The size of the anti-clumping signal is closely related to the difference of the initial isotope ratios of the indistinguishable atoms that have combined. Therefore, a measured statistical clumped isotope anomaly, relative to an expected (e.g. thermodynamical) clumped isotope composition, may allow assessment of the heterogeneity of the isotopic pools of atoms that are the substrate for formation of molecules. PMID:27535168

  6. Statistical clumped isotope signatures.

    PubMed

    Röckmann, T; Popa, M E; Krol, M C; Hofmann, M E G

    2016-01-01

    High precision measurements of molecules containing more than one heavy isotope may provide novel constraints on element cycles in nature. These so-called clumped isotope signatures are reported relative to the random (stochastic) distribution of heavy isotopes over all available isotopocules of a molecule, which is the conventional reference. When multiple indistinguishable atoms of the same element are present in a molecule, this reference is calculated from the bulk (≈average) isotopic composition of the involved atoms. We show here that this referencing convention leads to apparent negative clumped isotope anomalies (anti-clumping) when the indistinguishable atoms originate from isotopically different populations. Such statistical clumped isotope anomalies must occur in any system where two or more indistinguishable atoms of the same element, but with different isotopic composition, combine in a molecule. The size of the anti-clumping signal is closely related to the difference of the initial isotope ratios of the indistinguishable atoms that have combined. Therefore, a measured statistical clumped isotope anomaly, relative to an expected (e.g. thermodynamical) clumped isotope composition, may allow assessment of the heterogeneity of the isotopic pools of atoms that are the substrate for formation of molecules. PMID:27535168

  7. Signature extension: An approach to operational multispectral surveys

    NASA Technical Reports Server (NTRS)

    Nalepka, R. F.; Morgenstern, J. P.

    1973-01-01

    Two data processing techniques were suggested as applicable to the large area survey problem. One approach was to use unsupervised classification (clustering) techniques. Investigation of this method showed that since the method did nothing to reduce the signal variability, the use of this method would be very time consuming and possibly inaccurate as well. The conclusion is that unsupervised classification techniques of themselves are not a solution to the large area survey problem. The other method investigated was the use of signature extension techniques. Such techniques function by normalizing the data to some reference condition. Thus signatures from an isolated area could be used to process large quantities of data. In this manner, ground information requirements and computer training are minimized. Several signature extension techniques were tested. The best of these allowed signatures to be extended between data sets collected four days and 80 miles apart with an average accuracy of better than 90%.

  8. Dissecting genetic and environmental mutation signatures with model organisms.

    PubMed

    Segovia, Romulo; Tam, Annie S; Stirling, Peter C

    2015-08-01

    Deep sequencing has impacted on cancer research by enabling routine sequencing of genomes and exomes to identify genetic changes associated with carcinogenesis. Researchers can now use the frequency, type, and context of all mutations in tumor genomes to extract mutation signatures that reflect the driving mutational processes. Identifying mutation signatures, however, may not immediately suggest a mechanism. Consequently, several recent studies have employed deep sequencing of model organisms exposed to discrete genetic or environmental perturbations. These studies exploit the simpler genomes and availability of powerful genetic tools in model organisms to analyze mutation signatures under controlled conditions, forging mechanistic links between mutational processes and signatures. We discuss the power of this approach and suggest that many such studies may be on the horizon. PMID:25940384

  9. A proposed neutral line signature

    NASA Technical Reports Server (NTRS)

    Doxas, I.; Speiser, T. W.; Dusenbery, P. B.; Horton, W.

    1992-01-01

    An identifying signature is proposed for the existence and location of the neutral line in the magnetotail. The signature, abrupt density, and temperature changes in the Earthtail direction, was first discovered in test particle simulations. Such temperature variations have been observed in ISEE data (Huang et. al. 1992), but their connection to the possible existence of a neutral line in the tail has not yet been established. The proposed signature develops earlier than the ion velocity space ridge of Martin and Speiser (1988), but can only be seen by spacecraft in the vicinity of the neutral line, while the latter can locate a neutral line remotely.

  10. Signature surveillance of nuclear fuel

    SciTech Connect

    Bernatowicz, H.; Schoenig, F.C.

    1982-08-31

    Typical nuclear fuel material contains tramp ferromagnetic particles of random size and distribution. Also, selected amounts of paramagnetic or ferromagnetic material can be added at random or at known positions in the fuel material. The fuel material in its nonmagnetic container can be scanned by magnetic susceptibility change detecting apparatus to provide a unique signal waveform of the container of fuel material as a signature thereof. At subsequent times in its life, the container similarly can be scanned to provide subsequent signatures. Comparison of the signatures reveals any alteration or tampering with the fuel material.

  11. Scalable hardbody and plume optical signatures

    NASA Astrophysics Data System (ADS)

    Crow, Dennis R.; Hawes, Fred; Braunstein, Matthew; Coker, Charles F.; Smith, Thomas, Jr.

    2004-08-01

    The Fast Line-of-sight Imagery for Target and Exhaust Signatures (FLITES) is a High Performance Computing (HPC-CHSSI) and Missile Defense Agency (MDA) funded effort that provides a scalable program to compute highly resolved temporal, spatial, and spectral hardbody and plume optical signatures. Distributed processing capabilities are included to allow complex, high fidelity, solutions to be generated quickly generated. The distributed processing logic includes automated load balancing algorithms to facilitate scalability using large numbers of processors. To enhance exhaust plume optical signature capabilities, FLITES employs two different radiance transport algorithms. The first algorithm is the traditional Curtis-Godson bandmodel approach and is provided to support comparisons to historical results and high-frame rate production requirements. The second algorithm is the Quasi Bandmodel Line-by-line (QBL) approach, which uses randomly placed "cloned" spectral lines to yield highly resolved radiation spectra for increased accuracy while maintaining tractable runtimes. This capability will provide a significant advancement over the traditional SPURC/SIRRM radiance transport methodology.

  12. Signature detection and matching for document image retrieval.

    PubMed

    Zhu, Guangyu; Zheng, Yefeng; Doermann, David; Jaeger, Stefan

    2009-11-01

    As one of the most pervasive methods of individual identification and document authentication, signatures present convincing evidence and provide an important form of indexing for effective document image processing and retrieval in a broad range of applications. However, detection and segmentation of free-form objects such as signatures from clustered background is currently an open document analysis problem. In this paper, we focus on two fundamental problems in signature-based document image retrieval. First, we propose a novel multiscale approach to jointly detecting and segmenting signatures from document images. Rather than focusing on local features that typically have large variations, our approach captures the structural saliency using a signature production model and computes the dynamic curvature of 2D contour fragments over multiple scales. This detection framework is general and computationally tractable. Second, we treat the problem of signature retrieval in the unconstrained setting of translation, scale, and rotation invariant nonrigid shape matching. We propose two novel measures of shape dissimilarity based on anisotropic scaling and registration residual error and present a supervised learning framework for combining complementary shape information from different dissimilarity metrics using LDA. We quantitatively study state-of-the-art shape representations, shape matching algorithms, measures of dissimilarity, and the use of multiple instances as query in document image retrieval. We further demonstrate our matching techniques in offline signature verification. Extensive experiments using large real-world collections of English and Arabic machine-printed and handwritten documents demonstrate the excellent performance of our approaches. PMID:19762928

  13. Study of magnetic transient variations signature at equatorial region

    NASA Astrophysics Data System (ADS)

    Santos, J.; Trivedi, N.; Dutra, S.

    Transient variations in the H magnetic field component of magnetograms at high latitude are a common feature. They are associated with interaction process between solar wind and Earth's magnetic field. Abrupt changes in the solar wind interacting with Earth's magnetic field generate Alfvén and fast mode waves. The Alfvén wave doesn't propagate in the direction perpendicular to the geomagnetic field, so equatorial signatures are probably caused by fast mode waves. On the other hand, complex signatures observed at high latitudes represent a composition of Alfvén and fast mode waves. A second suggested propagation mechanism to low latitudes is the Earth-ionosphere wave-guide. In this work, geomagnetic data from the Brazilian magnetic stations at Belém/Tatuoca (BLM), Eusébio (EUS), Ji-Paraná (JIP), São luis (SLZ) and São Martinho da Serra (SMS) were used to look for equatorial signatures of magnetic transient events. We identified their morphological characteristics and time occurrence distribution. Satellite data (ACE and GOES) were used to see magnetosphere signatures and solar wind and interplanetary magnetic field conditions that increase the probability of occurrence for the equatorial events. Trivedi et al. (2002a) present evidence for corresponding signatures of TCV at Belém, São Luis, and Terezina and other stations under or nearby the equatorial electrojet. The conclusions of Trivedi et al. (2002a) are that equatorial signatures differ greatly from event to event; when the high-latitude transient events exhibited clear, strong, isolated signatures corresponding to TCVs, they generally detected isolated bipolar compressional signatures at geosynchronous orbit and transient impulses in equatorial ground magnetograms; when high-latitude events were quasiperiodic, weaker, spatially limited, or did not exhibit clear TCV signatures the equatorial signatures are difficult to identify; the equatorial signatures cannot be simply result from remote

  14. Signature-based image identification

    NASA Astrophysics Data System (ADS)

    Abdel-Mottaleb, Mohamed; Vaithilingam, Gandhimathi; Krishnamachari, Santhana

    1999-11-01

    The use of digital images and video is growing on the Internet and on consumer devices. Digital images and video are easy to manipulate, but this ease of manipulation makes tampering with digital content possible. Examples of the misuse of digital content include violating copyrights of the content and tampering with important material such as contents of video surveillance. In this paper we present an algorithm that extracts a binary signature from an image. This approach can be used to search for possible copyright violations by finding images with signatures close to that of a given image. The experimental results show that the algorithm can be very effective in helping users to retrieve sets of almost identical images from large collections of images. The signature can also be used for tamper detection. We will show that the signatures we extract are immune to quantization errors that result from compression and decompression.

  15. Retail applications of signature verification

    NASA Astrophysics Data System (ADS)

    Zimmerman, Thomas G.; Russell, Gregory F.; Heilper, Andre; Smith, Barton A.; Hu, Jianying; Markman, Dmitry; Graham, Jon E.; Drews, Clemens

    2004-08-01

    The dramatic rise in identity theft, the ever pressing need to provide convenience in checkout services to attract and retain loyal customers, and the growing use of multi-function signature captures devices in the retail sector provides favorable conditions for the deployment of dynamic signature verification (DSV) in retail settings. We report on the development of a DSV system to meet the needs of the retail sector. We currently have a database of approximately 10,000 signatures collected from 600 subjects and forgers. Previous work at IBM on DSV has been merged and extended to achieve robust performance on pen position data available from commercial point of sale hardware, achieving equal error rates on skilled forgeries and authentic signatures of 1.5% to 4%.

  16. Using what you get: dynamic physiologic signatures of critical illness

    PubMed Central

    Holder, Andre L.; Clermont, Gilles

    2015-01-01

    A physiologic signature can be defined as a consistent and robust collection of physiologic measurements characterizing a disease process and its temporal evolution. If a library of physiologic signatures of impending cardiopulmonary instability were available to clinicians caring for inpatients, many episodes of clinical decompensation and their downstream effects could potentially be averted. The development and resolution of cardiopulmonary instability are processes that take time to become clinically apparent, and the treatments provided take time to have an impact. The characterization of dynamic changes in hemodynamic and metabolic variables is implicit in the concept of physiologic signatures. Changes in vital signs such as blood pressure and heart rate, as well as measures of flow such as cardiac output are some of the standard variables used by clinicians to determine cardiopulmonary instability. When these primary variables are collected with high enough frequency to derive new variables, this data hierarchy can be used to development physiologic signatures. The construction of new variables from primary variables, and therefore the creation of physiologic signatures requires no new information; additional knowledge is extracted from data that already exists. It is possible to create physiologic signatures for each stage in the process of clinical decompensation and recovery to improve patient outcomes. PMID:25435482

  17. Ballastic signature identification systems study

    NASA Technical Reports Server (NTRS)

    Reich, A.; Hine, T. L.

    1976-01-01

    The results are described of an attempt to establish a uniform procedure for documenting (recording) expended bullet signatures as effortlessly as possible and to build a comprehensive library of these signatures in a form that will permit the automated comparison of a new suspect bullet with the prestored library. The ultimate objective is to achieve a standardized format that will permit nationwide interaction between police departments, crime laboratories, and other interested law enforcement agencies.

  18. Modeling ground vehicle acoustic signatures for analysis and synthesis

    SciTech Connect

    Haschke, G.; Stanfield, R.

    1995-07-01

    Security and weapon systems use acoustic sensor signals to classify and identify moving ground vehicles. Developing robust signal processing algorithms for this is expensive, particularly in presence of acoustic clutter or countermeasures. This paper proposes a parametric ground vehicle acoustic signature model to aid the system designer in understanding which signature features are important, developing corresponding feature extraction algorithms and generating low-cost, high-fidelity synthetic signatures for testing. The authors have proposed computer-generated acoustic signatures of armored, tracked ground vehicles to deceive acoustic-sensored smart munitions. They have developed quantitative measures of how accurately a synthetic acoustic signature matches those produced by actual vehicles. This paper describes parameters of the model used to generate these synthetic signatures and suggests methods for extracting these parameters from signatures of valid vehicle encounters. The model incorporates wide-bandwidth and narrow- bandwidth components that are modulated in a pseudo-random fashion to mimic the time dynamics of valid vehicle signatures. Narrow- bandwidth feature extraction techniques estimate frequency, amplitude and phase information contained in a single set of narrow frequency- band harmonics. Wide-bandwidth feature extraction techniques estimate parameters of a correlated-noise-floor model. Finally, the authors propose a method of modeling the time dynamics of the harmonic amplitudes as a means adding necessary time-varying features to the narrow-bandwidth signal components. The authors present results of applying this modeling technique to acoustic signatures recorded during encounters with one armored, tracked vehicle. Similar modeling techniques can be applied to security systems.

  19. Offline signature verification and skilled forgery detection using HMM and sum graph features with ANN and knowledge based classifier

    NASA Astrophysics Data System (ADS)

    Mehta, Mohit; Choudhary, Vijay; Das, Rupam; Khan, Ilyas

    2010-02-01

    Signature verification is one of the most widely researched areas in document analysis and signature biometric. Various methodologies have been proposed in this area for accurate signature verification and forgery detection. In this paper we propose a unique two stage model of detecting skilled forgery in the signature by combining two feature types namely Sum graph and HMM model for signature generation and classify them with knowledge based classifier and probability neural network. We proposed a unique technique of using HMM as feature rather than a classifier as being widely proposed by most of the authors in signature recognition. Results show a higher false rejection than false acceptance rate. The system detects forgeries with an accuracy of 80% and can detect the signatures with 91% accuracy. The two stage model can be used in realistic signature biometric applications like the banking applications where there is a need to detect the authenticity of the signature before processing documents like checks.

  20. The topographic signature of a Major Typhoon

    NASA Astrophysics Data System (ADS)

    Tseng, Chih-Ming; Lin, Ching-Weei; Dalla Fontana, Giancarlo; Tarolli, Paolo

    2013-04-01

    In August 2009, Typhoon Morakot, characterized by a cumulative rainfall up to 3000 mm in about three days, triggered thousands of landslides and debris flows in Taiwan. The availability of detailed LiDAR surveys before and after the event offers a great opportunity to deeply investigate the topographic signatures of a major Thyphoon, thus providing a way to better understand the Earth Surface Processes and the landscape evolution in a region affected by these phenomena and where the uplift rate is significant. We considered six small catchments, located in the Central Taiwan, affected during the Typhoon Morakot by a different degree of slope failures (totally affected by shallow and deep-seated landslides, and not affected by any erosion). For each of these catchment high resolution Digital Terrain Model (DTM) was derived by LiDAR data, before and after the Thypoon. The scaling regimes of local slope (S) versus drainage area (A) in a loglog diagram served as the basis upon which recognize topographic signatures. The results suggested that for the catchments affected by landslides it is possible to recognize in the third SA scaling regime a characteristic signature of the SA relation: the topographic gradient of the relation tends to vary a little (or slightly increase) increasing the drainage areas. According to literature (Stock and Dietrich, 2003; Tarolli et al., 2009) this behavior of the relation is due to channels incised by landslides and debris flows. Differently, for the catchments without slope failures this signature is not present. These results are interesting because they offer a real example of landscape evolution under rainfall forcing, demonstrating that a Maior Typhoon may significantly affect, in a short time, the SA scaling regimes. The possibility to obtain these information, immediately after an intense event, really represent a strategic tool for a first quantification of the processes that affected and significantly changed the earth surface

  1. 1 CFR 18.7 - Signature.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 1 General Provisions 1 2010-01-01 2010-01-01 false Signature. 18.7 Section 18.7 General Provisions... PREPARATION AND TRANSMITTAL OF DOCUMENTS GENERALLY § 18.7 Signature. The original and each duplicate original... stamped beneath the signature. Initialed or impressed signatures will not be accepted. Documents...

  2. 1 CFR 18.7 - Signature.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 1 General Provisions 1 2011-01-01 2011-01-01 false Signature. 18.7 Section 18.7 General Provisions... PREPARATION AND TRANSMITTAL OF DOCUMENTS GENERALLY § 18.7 Signature. The original and each duplicate original... stamped beneath the signature. Initialed or impressed signatures will not be accepted. Documents...

  3. Understanding mutagenesis through delineation of mutational signatures in human cancer

    DOE PAGESBeta

    Petljak, Mia; Alexandrov, Ludmil B.

    2016-06-01

    Each individual cell within a human body acquires a certain number of somatic mutations during a course of its lifetime. These mutations originate from a wide spectra of both endogenous and exogenous mutational processes that leave distinct patterns of mutations, termed mutational signatures, embedded within the genomes of all cells. In recent years, the vast amount of data produced by sequencing of cancer genomes was coupled with novel mathematical models and computational tools to generate the first comprehensive map of mutational signatures in human cancer. Up to date, >30 distinct mutational signatures have been identified, and etiologies have been proposedmore » for many of them. This paper provides a brief historical background on examination of mutational patterns in human cancer, summarizes the knowledge accumulated since introducing the concept of mutational signatures and discusses their future potential applications and perspectives within the field.« less

  4. Compound signature detection on LINCS L1000 big data

    PubMed Central

    Liu, Chenglin; Su, Jing; Yang, Fei; Wei, Kun; Ma, Jinwen; Zhou, Xiaobo

    2015-01-01

    The Library of Integrated Network-based Cellular Signatures (LINCS) L1000 big data provide gene expression profiles induced by over 10,000 compounds, shRNAs, and kinase inhibitors using the L1000 platform. We developed csNMF, a systematic compound signature discovery pipeline covering from raw L1000 data processing to drug screening and mechanism generation. The csNMF pipeline demonstrated better performance than the original L1000 pipeline. The discovered compound signatures of breast cancer were consistent with the LINCS KINOMEscan data and were clinically relevant. The csNMF pipeline provided a novel and complete tool to expedite signature-based drug discovery leveraging the LINCS L1000 resources. PMID:25609570

  5. Quantum blind dual-signature scheme without arbitrator

    NASA Astrophysics Data System (ADS)

    Li, Wei; Shi, Ronghua; Huang, Dazu; Shi, Jinjing; Guo, Ying

    2016-03-01

    Motivated by the elegant features of a bind signature, we suggest the design of a quantum blind dual-signature scheme with three phases, i.e., initial phase, signing phase and verification phase. Different from conventional schemes, legal messages are signed not only by the blind signatory but also by the sender in the signing phase. It does not rely much on an arbitrator in the verification phase as the previous quantum signature schemes usually do. The security is guaranteed by entanglement in quantum information processing. Security analysis demonstrates that the signature can be neither forged nor disavowed by illegal participants or attacker. It provides a potential application for e-commerce or e-payment systems with the current technology.

  6. Understanding mutagenesis through delineation of mutational signatures in human cancer.

    PubMed

    Petljak, Mia; Alexandrov, Ludmil B

    2016-06-01

    Each individual cell within a human body acquires a certain number of somatic mutations during a course of its lifetime. These mutations originate from a wide spectra of both endogenous and exogenous mutational processes that leave distinct patterns of mutations, termed mutational signatures, embedded within the genomes of all cells. In recent years, the vast amount of data produced by sequencing of cancer genomes was coupled with novel mathematical models and computational tools to generate the first comprehensive map of mutational signatures in human cancer. Up to date, >30 distinct mutational signatures have been identified, and etiologies have been proposed for many of them. This review provides a brief historical background on examination of mutational patterns in human cancer, summarizes the knowledge accumulated since introducing the concept of mutational signatures and discusses their future potential applications and perspectives within the field. PMID:27207657

  7. Quantum messages with signatures forgeable in arbitrated quantum signature schemes

    NASA Astrophysics Data System (ADS)

    Kim, Taewan; Choi, Jeong Woon; Jho, Nam-Su; Lee, Soojoon

    2015-02-01

    Even though a method to perfectly sign quantum messages has not been known, the arbitrated quantum signature scheme has been considered as one of the good candidates. However, its forgery problem has been an obstacle to the scheme becoming a successful method. In this paper, we consider one situation, which is slightly different from the forgery problem, that we use to check whether at least one quantum message with signature can be forged in a given scheme, although all the messages cannot be forged. If there are only a finite number of forgeable quantum messages in the scheme, then the scheme can be secured against the forgery attack by not sending forgeable quantum messages, and so our situation does not directly imply that we check whether the scheme is secure against the attack. However, if users run a given scheme without any consideration of forgeable quantum messages, then a sender might transmit such forgeable messages to a receiver and in such a case an attacker can forge the messages if the attacker knows them. Thus it is important and necessary to look into forgeable quantum messages. We show here that there always exists such a forgeable quantum message-signature pair for every known scheme with quantum encryption and rotation, and numerically show that there are no forgeable quantum message-signature pairs that exist in an arbitrated quantum signature scheme.

  8. Pattern recognition algorithm reveals how birds evolve individual egg pattern signatures.

    PubMed

    Stoddard, Mary Caswell; Kilner, Rebecca M; Town, Christopher

    2014-01-01

    Pattern-based identity signatures are commonplace in the animal kingdom, but how they are recognized is poorly understood. Here we develop a computer vision tool for analysing visual patterns, NATUREPATTERNMATCH, which breaks new ground by mimicking visual and cognitive processes known to be involved in recognition tasks. We apply this tool to a long-standing question about the evolution of recognizable signatures. The common cuckoo (Cuculus canorus) is a notorious cheat that sneaks its mimetic eggs into nests of other species. Can host birds fight back against cuckoo forgery by evolving highly recognizable signatures? Using NATUREPATTERNMATCH, we show that hosts subjected to the best cuckoo mimicry have evolved the most recognizable egg pattern signatures. Theory predicts that effective pattern signatures should be simultaneously replicable, distinctive and complex. However, our results reveal that recognizable signatures need not incorporate all three of these features. Moreover, different hosts have evolved effective signatures in diverse ways. PMID:24939367

  9. Accounting for dependencies in regionalized signatures for predictions in ungauged catchments

    NASA Astrophysics Data System (ADS)

    Almeida, Susana; Le Vine, Nataliya; McIntyre, Neil; Wagener, Thorsten; Buytaert, Wouter

    2016-02-01

    A recurrent problem in hydrology is the absence of streamflow data to calibrate rainfall-runoff models. A commonly used approach in such circumstances conditions model parameters on regionalized response signatures. While several different signatures are often available to be included in this process, an outstanding challenge is the selection of signatures that provide useful and complementary information. Different signatures do not necessarily provide independent information and this has led to signatures being omitted or included on a subjective basis. This paper presents a method that accounts for the inter-signature error correlation structure so that regional information is neither neglected nor double-counted when multiple signatures are included. Using 84 catchments from the MOPEX database, observed signatures are regressed against physical and climatic catchment attributes. The derived relationships are then utilized to assess the joint probability distribution of the signature regionalization errors that is subsequently used in a Bayesian procedure to condition a rainfall-runoff model. The results show that the consideration of the inter-signature error structure may improve predictions when the error correlations are strong. However, other uncertainties such as model structure and observational error may outweigh the importance of these correlations. Further, these other uncertainties cause some signatures to appear repeatedly to be misinformative.

  10. Isotopic signatures by bulk analyses

    SciTech Connect

    Efurd, D.W.; Rokop, D.J.

    1997-12-01

    Los Alamos National Laboratory has developed a series of measurement techniques for identification of nuclear signatures by analyzing bulk samples. Two specific applications for isotopic fingerprinting to identify the origin of anthropogenic radioactivity in bulk samples are presented. The first example is the analyses of environmental samples collected in the US Arctic to determine the impact of dumping of radionuclides in this polar region. Analyses of sediment and biota samples indicate that for the areas sampled the anthropogenic radionuclide content of sediments was predominantly the result of the deposition of global fallout. The anthropogenic radionuclide concentrations in fish, birds and mammals were very low. It can be surmised that marine food chains are presently not significantly affected. The second example is isotopic fingerprinting of water and sediment samples from the Rocky Flats Facility (RFP). The largest source of anthropogenic radioactivity presently affecting surface-waters at RFP is the sediments that are currently residing in the holding ponds. One gram of sediment from a holding pond contains approximately 50 times more plutonium than 1 liter of water from the pond. Essentially 100% of the uranium in Ponds A-1 and A-2 originated as depleted uranium. The largest source of radioactivity in the terminal Ponds A-4, B-5 and C-2 was naturally occurring uranium and its decay product radium. The uranium concentrations in the waters collected from the terminal ponds contained 0.05% or less of the interim standard calculated derived concentration guide for uranium in waters available to the public. All of the radioactivity observed in soil, sediment and water samples collected at RFP was naturally occurring, the result of processes at RFP or the result of global fallout. No extraneous anthropogenic alpha, beta or gamma activities were detected. The plutonium concentrations in Pond C-2 appear to vary seasonally.

  11. Multidimensional signatures in antimicrobial peptides

    PubMed Central

    Yount, Nannette Y.; Yeaman, Michael R.

    2004-01-01

    Conventional analyses distinguish between antimicrobial peptides by differences in amino acid sequence. Yet structural paradigms common to broader classes of these molecules have not been established. The current analyses examined the potential conservation of structural themes in antimicrobial peptides from evolutionarily diverse organisms. Using proteomics, an antimicrobial peptide signature was discovered to integrate stereospecific sequence patterns and a hallmark three-dimensional motif. This striking multidimensional signature is conserved among disulfide-containing antimicrobial peptides spanning biological kingdoms, and it transcends motifs previously limited to defined peptide subclasses. Experimental data validating this model enabled the identification of previously unrecognized antimicrobial activity in peptides of known identity. The multidimensional signature model provides a unifying structural theme in broad classes of antimicrobial peptides, will facilitate discovery of antimicrobial peptides as yet unknown, and offers insights into the evolution of molecular determinants in these and related host defense effector molecules. PMID:15118082

  12. Graph Analytics for Signature Discovery

    SciTech Connect

    Hogan, Emilie A.; Johnson, John R.; Halappanavar, Mahantesh; Lo, Chaomei

    2013-06-01

    Within large amounts of seemingly unstructured data it can be diffcult to find signatures of events. In our work we transform unstructured data into a graph representation. By doing this we expose underlying structure in the data and can take advantage of existing graph analytics capabilities, as well as develop new capabilities. Currently we focus on applications in cybersecurity and communication domains. Within cybersecurity we aim to find signatures for perpetrators using the pass-the-hash attack, and in communications we look for emails or phone calls going up or down a chain of command. In both of these areas, and in many others, the signature we look for is a path with certain temporal properties. In this paper we discuss our methodology for finding these temporal paths within large graphs.

  13. Heterogeneous access and processing of EO-Data on a Cloud based Infrastructure delivering operational Products

    NASA Astrophysics Data System (ADS)

    Niggemann, F.; Appel, F.; Bach, H.; de la Mar, J.; Schirpke, B.; Dutting, K.; Rucker, G.; Leimbach, D.

    2015-04-01

    To address the challenges of effective data handling faced by Small and Medium Sized Enterprises (SMEs) a cloud-based infrastructure for accessing and processing of Earth Observation(EO)-data has been developed within the project APPS4GMES(www.apps4gmes.de). To gain homogenous multi mission data access an Input Data Portal (IDP) been implemented on this infrastructure. The IDP consists of an Open Geospatial Consortium (OGC) conformant catalogue, a consolidation module for format conversion and an OGC-conformant ordering framework. Metadata of various EO-sources and with different standards is harvested and transferred to an OGC conformant Earth Observation Product standard and inserted into the catalogue by a Metadata Harvester. The IDP can be accessed for search and ordering of the harvested datasets by the services implemented on the cloud infrastructure. Different land-surface services have been realised by the project partners, using the implemented IDP and cloud infrastructure. Results of these are customer ready products, as well as pre-products (e.g. atmospheric corrected EO data), serving as a basis for other services. Within the IDP an automated access to ESA's Sentinel-1 Scientific Data Hub has been implemented. Searching and downloading of the SAR data can be performed in an automated way. With the implementation of the Sentinel-1 Toolbox and own software, for processing of the datasets for further use, for example for Vista's snow monitoring, delivering input for the flood forecast services, can also be performed in an automated way. For performance tests of the cloud environment a sophisticated model based atmospheric correction and pre-classification service has been implemented. Tests conducted an automated synchronised processing of one entire Landsat 8 (LS-8) coverage for Germany and performance comparisons to standard desktop systems. Results of these tests, showing a performance improvement by the factor of six, proved the high flexibility and

  14. Topological Signatures for Population Admixture

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Topological Signatures for Population AdmixtureDeniz Yorukoglu1, Filippo Utro1, David Kuhn2, Saugata Basu3 and Laxmi Parida1* Abstract Background: As populations with multi-linear transmission (i.e., mixing of genetic material from two parents, say) evolve over generations, the genetic transmission...

  15. Invisibly Sanitizable Digital Signature Scheme

    NASA Astrophysics Data System (ADS)

    Miyazaki, Kunihiko; Hanaoka, Goichiro; Imai, Hideki

    A digital signature does not allow any alteration of the document to which it is attached. Appropriate alteration of some signed documents, however, should be allowed because there are security requirements other than the integrity of the document. In the disclosure of official information, for example, sensitive information such as personal information or national secrets is masked when an official document is sanitized so that its nonsensitive information can be disclosed when it is requested by a citizen. If this disclosure is done digitally by using the current digital signature schemes, the citizen cannot verify the disclosed information because it has been altered to prevent the leakage of sensitive information. The confidentiality of official information is thus incompatible with the integrity of that information, and this is called the digital document sanitizing problem. Conventional solutions such as content extraction signatures and digitally signed document sanitizing schemes with disclosure condition control can either let the sanitizer assign disclosure conditions or hide the number of sanitized portions. The digitally signed document sanitizing scheme we propose here is based on the aggregate signature derived from bilinear maps and can do both. Moreover, the proposed scheme can sanitize a signed document invisibly, that is, no one can distinguish whether the signed document has been sanitized or not.

  16. Disaster relief through composite signatures

    NASA Astrophysics Data System (ADS)

    Hawley, Chadwick T.; Hyde, Brian; Carpenter, Tom; Nichols, Steve

    2012-06-01

    A composite signature is a group of signatures that are related in such a way to more completely or further define a target or operational endeavor at a higher fidelity. This paper builds on previous work developing innovative composite signatures associated with civil disasters, including physical, chemical and pattern/behavioral. For the composite signature approach to be successful it requires effective data fusion and visualization. This plays a key role in both preparedness and the response and recovery which are critical to saving lives. Visualization tools enhance the overall understanding of the crisis by pulling together and analyzing the data, and providing a clear and complete analysis of the information to the organizations/agencies dependant on it for a successful operation. An example of this, Freedom Web, is an easy-to-use data visualization and collaboration solution for use in homeland security, emergency preparedness, situational awareness, and event management. The solution provides a nationwide common operating picture for all levels of government through a web based, map interface. The tool was designed to be utilized by non-geospatial experts and is easily tailored to the specific needs of the users. Consisting of standard COTS and open source databases and a web server, users can view, edit, share, and highlight information easily and quickly through a standard internet browser.

  17. Twin signal signature sensing: Application to shorted winding monitoring, detection and localization

    SciTech Connect

    Streifel, R.J.; Marks, R.J.; El-Sharkawi, A.E.; Kerszenbaum, I.

    1995-12-31

    Using twin signal sensing we propose a method to monitor, detect and localize shorts in power system devices with windings: including rotors, transformers and motors. There has, to date, been no effective way to do so. The most obvious approach, time domain reflectometry, fails due to the reactive coupling of the windings. Twin signal signature sensing of shorts results from identical signals being simultaneously injected in both sides of the windings. The reflected signals are measured and the difference amplified to produce the signature signal. The signature signal characterizes the current state of the windings. When winding shorts are present, the electrical characteristics of the device will be different and thus the signature signal will also change. The changes in the signature signal can be monitored to detect shorted windings. While a device is in operation, the signature signals can be monitored and the development of winding shorts can be diagnosed through the process of novelty detection. After a device is cleaned or otherwise known to be functioning correctly (no winding shorts), signature signals can be collected which represent the healthy device. If a sufficient number of signals can be collected, the signal space representing healthy windings can be characterized. A detection surface can be placed around the healthy signature signals to provide a partition of the signal space into two regions: healthy and faulty. Any signature signal which is not within the healthy signature partition will indicate a faulted device.

  18. Discovery of Brownleeite: a New Manganese Silicide Mineral in an Interplanetary Dust Particle

    NASA Technical Reports Server (NTRS)

    Keller, Lindsay P.; Nakamura-Messenger, Keiko; Clemett, Simon J.; Messenger, Scott; Jones, John H.; Palma, Russell L.; Pepin, Robert O.; Klock, Wolfgang; Zolensky, Michael E.; Tatsuoka, Hirokazu

    2011-01-01

    The Earth accretes approximately 40,000 tons of cosmic dust annually, originating mainly from the disintegration of comets and collisions among asteroids. This cosmic dust, also known as interplanetary dust particles (IDPs), is a subject of intense interest since it is made of the original building blocks of our Solar System. Although the specific parent bodies of IDPs are unknown, the anhydrous chondritic-porous IDPs (CP-IDPs) subset has been potentially linked to a cometary source. The CP-IDPs are extremely primitive materials based on their unequilibrated mineralogy, C-rich chemistry, and anomalous isotopic signatures. In particular, some CP-IDPs escaped the thermal, aqueous and impact shock processing that has modified or destroyed the original mineralogy of meteorites. Thus, the CP-IDPs represent some of the most primitive solar system materials available for laboratory study. Most CP-IDPs are comprised of minerals that are common on Earth. However, in the course of an examination of one of the CP-IDPs, we encountered three sub-micrometer sized grains of manganese silicide (MnSi), a phase that has heretofore not been found in nature. In the seminar, we would like to focus on IDP studies and this manganese silicide phase that has been approved as the first new mineral identified from a comet by the International Mineralogical Association (IMA) in 2008. The mineral is named in honour of Donald E. Brownlee, an American astronomer and a founder of the field of cosmic dust research who is the principal investigator of the NASA Stardust Mission that collected dust samples from Comet 81P/Wild-2 and returned them to Earth. Much of our current view and understanding of the early solar system would not exist without the pioneering work of professor Don Brownlee in the study of IDPs.

  19. Block truncation signature coding for hyperspectral analysis

    NASA Astrophysics Data System (ADS)

    Chakravarty, Sumit; Chang, Chein-I.

    2008-08-01

    This paper introduces a new signature coding which is designed based on the well-known Block Truncation Coding (BTC). It comprises of bit-maps of the signature blocks generated by different threshold criteria. Two new BTC-based algorithms are developed for signature coding, to be called Block Truncation Signature Coding (BTSC) and 2-level BTSC (2BTSC). In order to compare the developed BTC based algorithms with current binary signature coding schemes such as Spectral Program Analysis Manager (SPAM) developed by Mazer et al. and Spectral Feature-based Binary Coding (SFBC) by Qian et al., three different thresholding functions, local block mean, local block gradient, local block correlation are derived to improve the BTSC performance where the combined bit-maps generated by these thresholds can provide better spectral signature characterization. Experimental results reveal that the new BTC-based signature coding performs more effectively in characterizing spectral variations than currently available binary signature coding methods.

  20. 17 CFR 232.302 - Signatures.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 2 2013-04-01 2013-04-01 false Signatures. 232.302 Section 232.302 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION REGULATION S-T-GENERAL RULES AND REGULATIONS FOR ELECTRONIC FILINGS Preparation of Electronic Submissions § 232.302 Signatures. (a) Required signatures to, or within,...

  1. Polarization signatures of airborne particulates

    NASA Astrophysics Data System (ADS)

    Raman, Prashant; Fuller, Kirk A.; Gregory, Don A.

    2013-07-01

    Exploratory research has been conducted with the aim of completely determining the polarization signatures of selected particulates as a function of wavelength. This may lead to a better understanding of the interaction between electromagnetic radiation and such materials, perhaps leading to the point detection of bio-aerosols present in the atmosphere. To this end, a polarimeter capable of measuring the complete Mueller matrix of highly scattering samples in transmission and reflection (with good spectral resolution from 300 to 1100 nm) has been developed. The polarization properties of Bacillus subtilis (surrogate for anthrax spore) are compared to ambient particulate matter species such as pollen, dust, and soot. Differentiating features in the polarization signatures of these samples have been identified, thus demonstrating the potential applicability of this technique for the detection of bio-aerosol in the ambient atmosphere.

  2. The doctrine of signatures: a historical, philosophical and scientific view (I).

    PubMed

    Richardson-Boedler, C

    1999-10-01

    The evolution of the Doctrine of Signatures is presented, with reference to a physical as well as mental/spiritual mode of relating nature's medicinal substances to the human symptoms. Symbolism, intuition, biological observation, and the study of the medicinal properties serve as guides in the Doctrine of Signatures; modern science offers additional dimensions by relating physiological processes to physiology of disease. PMID:10582648

  3. Toward a Signature Pedagogy in Educational Leadership Preparation and Program Assessment

    ERIC Educational Resources Information Center

    Black, William R.; Murtadha, Khaula

    2007-01-01

    In this article, we work towards developing a signature pedagogy for educational leadership preparation programs. A signature pedagogy that engenders theory-building processes and leadership practices includes complex case studies, inquiry-centered internships, collaborative and interdisciplinary leadership institutes, and continuous assessments…

  4. Electron Signatures and Alfven Waves

    NASA Technical Reports Server (NTRS)

    Andersson, Laila; Ivchenko, N.; Clemmons, J.; Namgaladze, A. A.; Gustavsson, B.; Wahlund, J.-E.; Eliasson, L.; Yurik, R. Y.

    2000-01-01

    The electron signatures which appear together with Alfven waves observed by the Freja satellite in the auroral region are reported. Precipitating electrons are detected both with and just before the wave. The observed Alfven waves must therefore be capable of accelerating electrons to higher energies than the local phase velocity of these waves in order for the electrons to move in advance of the wave. The characteristics of such electrons suggest electrons moving infront of the wave have characteristics of origin from warmer and lower density plasma while the electrons moving with the wave have characteristics of cooler and denser plasma. The pitch angle distribution of the electrons moving with the wave indicates that there is continuous acceleration of new particles by the wave, i.e. a propagating Alfven wave is the source of these electrons . A simple model of a propagating source is made to model the electrons that are moving in advance of the wave. Depending on whether accelerated electrons leave the wave above or below the altitude where the Alfven wave has the highest phase velocity, the detected electron signatures will be different; electron dispersion or potential drop like, respectively. It is shown that the Alfven wave acceleration can create electron signatures similar to inverted-V structures.

  5. Selection signatures in Shetland ponies.

    PubMed

    Frischknecht, M; Flury, C; Leeb, T; Rieder, S; Neuditschko, M

    2016-06-01

    Shetland ponies were selected for numerous traits including small stature, strength, hardiness and longevity. Despite the different selection criteria, Shetland ponies are well known for their small stature. We performed a selection signature analysis including genome-wide SNPs of 75 Shetland ponies and 76 large-sized horses. Based upon this dataset, we identified a selection signature on equine chromosome (ECA) 1 between 103.8 Mb and 108.5 Mb. A total of 33 annotated genes are located within this interval including the IGF1R gene at 104.2 Mb and the ADAMTS17 gene at 105.4 Mb. These two genes are well known to have a major impact on body height in numerous species including humans. Homozygosity mapping in the Shetland ponies identified a region with increased homozygosity between 107.4 Mb and 108.5 Mb. None of the annotated genes in this region have so far been associated with height. Thus, we cannot exclude the possibility that the identified selection signature on ECA1 is associated with some trait other than height, for which Shetland ponies were selected. PMID:26857482

  6. Electronic health records: what does your signature signify?

    PubMed

    Victoroff Md, Michael S

    2012-01-01

    Electronic health records serve multiple purposes, including clinical communication, legal documentation, financial transaction capture, research and analytics. Electronic signatures attached to entries in EHRs have different logical and legal meanings for different users. Some of these are vestiges from historic paper formats that require reconsideration. Traditionally accepted functions of signatures, such as identity verification, attestation, consent, authorization and non-repudiation can become ambiguous in the context of computer-assisted workflow processes that incorporate functions like logins, auto-fill and audit trails. This article exposes the incompatibility of expectations among typical users of electronically signed information. PMID:22888846

  7. Reading the Signatures of Extrasolar Planets in Debris Disks

    NASA Technical Reports Server (NTRS)

    Kuchner, Marc J.

    2009-01-01

    An extrasolar planet sculpts the famous debris dish around Fomalhaut; probably ma ny other debris disks contain planets that we could locate if only we could better recognize their signatures in the dust that surrounds them. But the interaction between planets and debris disks involves both orbital resonances and collisions among grains and rocks in the disks --- difficult processes to model simultanemus]y. I will describe new 3-D models of debris disk dynamics that incorporate both collisions and resonant trapping of dust for the first time, allowing us to decode debris disk images and read the signatures of the planets they contain.

  8. Infrared signature studies of aerospace vehicles

    NASA Astrophysics Data System (ADS)

    Mahulikar, Shripad P.; Sonawane, Hemant R.; Arvind Rao, G.

    2007-10-01

    Infrared (IR) emissions from aircraft are used to detect, track, and lock-on to the target. MAN Portable Air Defence Systems (MANPADS) have emerged as a major cause of aircraft and helicopter loss. Therefore, IR signature studies are important to counter this threat for survivability enhancement, and are an important aspect of stealth technology. This paper reviews contemporary developments in this discipline, with particular emphasis on IR signature prediction from aerospace vehicles. The role of atmosphere in IR signature analysis, and relation between IR signature level and target susceptibility are illustrated. Also, IR signature suppression systems and countermeasure techniques are discussed, to highlight their effectiveness and implications in terms of penalties.

  9. Automatic classification of spatial signatures on semiconductor wafermaps

    SciTech Connect

    Tobin, K.W.; Gleason, S.S.; Karnowski, T.P.; Cohen, S.L.; Lakhani, F.

    1997-03-01

    This paper describes Spatial Signature Analysis (SSA), a cooperative research project between SEMATECH and Oak Ridge National Laboratory for automatically analyzing and reducing semiconductor wafermap defect data to useful information. Trends toward larger wafer formats and smaller critical dimensions have caused an exponential increase in the volume of visual and parametric defect data which must be analyzed and stored, therefore necessitating the development of automated tools for wafer defect analysis. Contamination particles that did not create problems with 1 micron design rules can now be categorized as killer defects. SSA is an automated wafermap analysis procedure which performs a sophisticated defect clustering and signature classification of electronic wafermaps. This procedure has been realized in a software system that contains a signature classifier that is user-trainable. Known examples of historically problematic process signatures are added to a training database for the classifier. Once a suitable training set has been established, the software can automatically segment and classify multiple signatures form a standard electronic wafermap file into user-defined categories. It is anticipated that successful integration of this technology with other wafer monitoring strategies will result in reduced time-to-discovery and ultimately improved product yield.

  10. ARMOR Dual-Polarimetric Radar Observations of Tornadic Debris Signatures

    NASA Technical Reports Server (NTRS)

    Petersen, W. A,; Carey, L. D.; Knupp, K. R.; Schultz, C.; Johnson, E.

    2008-01-01

    During the Super-Tuesday tornado outbreak of 5-6 February 2008, two EF-4 tornadoes occurred in Northern Alabama within 75 km range of the University of Alabama in Huntsville (UAH) Advanced Radar for Meteorological and Operational Research (ARMOR, C-band dual-polarimetric). This study will present an analysis of ARMOR radar-indicated dual-polarimetric tornadic debris signatures. The debris signatures were associated with spatially-confined large decreases in the copolar correlation coefficient (rho(hv)hv) that were embedded within broader mesocyclone "hook" signatures. These debris signatures were most obviously manifest during the F-3 to F-4 intensity stages of the tornado(s) and extended to altitudes of approximately 3 km. The rho(hv) signatures of the tornadic debris were the most easily distinguished relative to other polarimetric and radial velocity parameters (e.g., associated with large hail and/or the incipient mesocyclone). Based on our analysis, and consistent with the small number of studies found in the literature, we conclude that dual-polarimetric radar data offer at least the possibility for enhancing specificity and confidence in the process of issuing tornado warnings based only on radar detection of threatening circulation features.

  11. Arbitrated Quantum Signature Scheme with Continuous-Variable Coherent States

    NASA Astrophysics Data System (ADS)

    Guo, Ying; Feng, Yanyan; Huang, Dazu; Shi, Jinjing

    2016-04-01

    Motivated by the revealing features of the continuous-variable (CV) quantum cryptography, we suggest an arbitrated quantum signature (AQS) protocol with CV coherent states. It involves three participants, i.e., the signer Alice, the verifier Bob and the arbitrator Charlie who is trustworthy by Alice and Bob. Three phases initializing phase, signing phase and verifying phase are included in our protocol. The security of the signature scheme is guaranteed by the generation of the shared keys via the CV-based quantum key distribution (CV-QKD) and the implementation process of the CV-based quantum teleportation as well. Security analysis demonstrates that the signature can be neither forged by anyone nor disavowed by the receiver and signer. Moreover, the authenticity and integrality of the transmitted messages can be ensured. The paper shows that a potential high-speed quantum signature scheme with high detection efficiency and repetition rate can be realized when compared to the discrete-variable (DV) quantum signature scheme attributing to the well characteristics of CV-QKD.

  12. Identification of selection signatures in livestock species

    PubMed Central

    de Simoni Gouveia, João José; da Silva, Marcos Vinicius Gualberto Barbosa; Paiva, Samuel Rezende; de Oliveira, Sônia Maria Pinheiro

    2014-01-01

    The identification of regions that have undergone selection is one of the principal goals of theoretical and applied evolutionary genetics. Such studies can also provide information about the evolutionary processes involved in shaping genomes, as well as physical and functional information about genes/genomic regions. Domestication followed by breed formation and selection schemes has allowed the formation of very diverse livestock breeds adapted to a wide variety of environments and with special characteristics. The advances in genomics in the last five years have enabled the development of several methods to detect selection signatures and have resulted in the publication of a considerable number of studies involving livestock species. The aims of this review are to describe the principal effects of natural/artificial selection on livestock genomes, to present the main methods used to detect selection signatures and to discuss some recent results in this area. This review should be useful also to research scientists working with wild animals/non-domesticated species and plant biologists working with breeding and evolutionary biology. PMID:25071397

  13. Neurofunctional Signature of Hyperfamiliarity for Unknown Faces

    PubMed Central

    Negro, Elisa; D’Agata, Federico; Caroppo, Paola; Coriasco, Mario; Ferrio, Federica; Celeghin, Alessia; Diano, Matteo; Rubino, Elisa; de Gelder, Beatrice; Rainero, Innocenzo; Pinessi, Lorenzo; Tamietto, Marco

    2015-01-01

    Hyperfamiliarity for unknown faces is a rare selective disorder that consists of the disturbing and abnormal feeling of familiarity for unknown faces, while recognition of known faces is normal. In one such patient we investigated with a multimodal neuroimaging design the hitherto undescribed neural signature associated with hyperfamiliarity feelings. Behaviorally, signal detection methods revealed that the patient’s discrimination sensitivity between familiar and unfamiliar faces was significantly lower than that of matched controls, and her response criterion for familiarity decisions was significantly more liberal. At the neural level, while morphometric analysis and single-photon emission CT (SPECT) showed the atrophy and hypofunctioning of the left temporal regions, functional magnetic resonance imaging (fMRI) revealed that hyperfamiliarity feelings were selectively associated to enhanced activity in the right medial and inferior temporal cortices. We therefore characterize the neurofunctional signature of hyperfamiliarity for unknown faces as related to the loss of coordinated activity between the complementary face processing functions of the left and right temporal lobes. PMID:26154253

  14. Automatic human micro-Doppler signature separation by Hough transform

    NASA Astrophysics Data System (ADS)

    Zhang, Jun; Jin, Tian; Qiu, Lei; Zhou, Zhimin

    2015-12-01

    The micro-Doppler signature is one of the most prominent information for target classification and identification. As Hough transform (HT) is an efficient tool for detecting weak straight target traces in the image, an HT based algorithm is proposed for micro-Doppler signature separation of multiple persons. Few seconds data is processed at one time to ensure human motion traces approximate to straight lines in the radar slow time-range image. Taking HT to the slow time-range image, each human's motion trace can be recovered through recursively searching the peaks in HT space. Applying time-frequency transform to the range cells around each recovered line, the human micro-Doppler signature can be achieved and separated. Experimental results are given to illustrate the validity of the proposed algorithm.

  15. Shell Buckling Design Criteria Based on Manufacturing Imperfection Signatures

    NASA Technical Reports Server (NTRS)

    Hilburger, Mark W.; Nemeth, Michael P.; Starnes, James H., Jr.

    2004-01-01

    An analysis-based approach .for developing shell-buckling design criteria for laminated-composite cylindrical shells that accurately accounts for the effects of initial geometric imperfections is presented. With this approach, measured initial geometric imperfection data from six graphite-epoxy shells are used to determine a manufacturing-process-specific imperfection signature for these shells. This imperfection signature is then used as input into nonlinear finite-element analyses. The imperfection signature represents a "first-approximation" mean imperfection shape that is suitable for developing preliminary-design data. Comparisons of test data and analytical results obtained by using several different imperfection shapes are presented for selected shells. Overall, the results indicate that the analysis-based approach presented for developing reliable preliminary-design criteria has the potential to provide improved, less conservative buckling-load estimates, and to reduce the weight and cost of developing buckling-resistant shell structures.

  16. Spectral signature selection for mapping unvegetated soils

    NASA Technical Reports Server (NTRS)

    May, G. A.; Petersen, G. W.

    1975-01-01

    Airborne multispectral scanner data covering the wavelength interval from 0.40-2.60 microns were collected at an altitude of 1000 m above the terrain in southeastern Pennsylvania. Uniform training areas were selected within three sites from this flightline. Soil samples were collected from each site and a procedure developed to allow assignment of scan line and element number from the multispectral scanner data to each sampling location. These soil samples were analyzed on a spectrophotometer and laboratory spectral signatures were derived. After correcting for solar radiation and atmospheric attenuation, the laboratory signatures were compared to the spectral signatures derived from these same soils using multispectral scanner data. Both signatures were used in supervised and unsupervised classification routines. Computer-generated maps using the laboratory and multispectral scanner derived signatures resulted in maps that were similar to maps resulting from field surveys. Approximately 90% agreement was obtained between classification maps produced using multispectral scanner derived signatures and laboratory derived signatures.

  17. A new quantum blind signature with unlinkability

    NASA Astrophysics Data System (ADS)

    Shi, Wei-Min; Zhang, Jian-Biao; Zhou, Yi-Hua; Yang, Yu-Guang

    2015-08-01

    Recently, some quantum blind signature protocols have been proposed. However, the previous schemes cannot satisfy the unlinkability requirement. To overcome the drawback of unlinkability in the previous schemes, we propose a new quantum blind signature based on Bell states with the help of an authentic party. In this paper, we provide a method to inject a randomizing factor into a message when it is signed by the signer and then get rid of the blind factor from the blinded signature when it is verified by the verifier. Even when the message owner publishes the message-signature pair, the signer cannot identify the association between the message-signature pair and the blind signature he generated. Therefore, our scheme really realizes unlinkability property. At last, analysis results show that this scheme satisfies the basis security requirements of a weak signature such as no-counterfeiting, no-disavowing, blindness and traceability, and our total efficiency is not less than the previous schemes.

  18. Quantum proxy signature scheme with public verifiability

    NASA Astrophysics Data System (ADS)

    Zhou, Jingxian; Zhou, Yajian; Niu, Xinxin; Yang, Yixian

    2011-10-01

    In recent years, with the development of quantum cryptography, quantum signature has also made great achievement. However, the effectiveness of all the quantum signature schemes reported in the literature can only be verified by a designated person. Therefore, its wide applications are limited. For solving this problem, a new quantum proxy signature scheme using EPR quantum entanglement state and unitary transformation to generate proxy signature is presented. Proxy signer announces his public key when he generates the final signature. According to the property of unitary transformation and quantum one-way function, everyone can verify whether the signature is effective or not by the public key. So the quantum proxy signature scheme in our paper can be public verified. The quantum key distribution and one-time pad encryption algorithm guarantee the unconditional security of this scheme. Analysis results show that this new scheme satisfies strong non-counterfeit and strong non-disavowal.

  19. Thermal imaging as a biometrics approach to facial signature authentication.

    PubMed

    Guzman, A M; Goryawala, M; Wang, Jin; Barreto, A; Andrian, J; Rishe, N; Adjouadi, M

    2013-01-01

    A new thermal imaging framework with unique feature extraction and similarity measurements for face recognition is presented. The research premise is to design specialized algorithms that would extract vasculature information, create a thermal facial signature and identify the individual. The proposed algorithm is fully integrated and consolidates the critical steps of feature extraction through the use of morphological operators, registration using the Linear Image Registration Tool and matching through unique similarity measures designed for this task. The novel approach at developing a thermal signature template using four images taken at various instants of time ensured that unforeseen changes in the vasculature over time did not affect the biometric matching process as the authentication process relied only on consistent thermal features. Thirteen subjects were used for testing the developed technique on an in-house thermal imaging system. The matching using the similarity measures showed an average accuracy of 88.46% for skeletonized signatures and 90.39% for anisotropically diffused signatures. The highly accurate results obtained in the matching process clearly demonstrate the ability of the thermal infrared system to extend in application to other thermal imaging based systems. Empirical results applying this approach to an existing database of thermal images proves this assertion. PMID:22801524

  20. Molecular signatures from omics data: From chaos to consensus

    PubMed Central

    Sung, Jaeyun; Wang, Yuliang; Chandrasekaran, Sriram; Witten, Daniela M; Price, Nathan D

    2012-01-01

    In the past 15 years, new “omics” technologies have made it possible to obtain high-resolution molecular snapshots of organisms, tissues, and even individual cells at various disease states and experimental conditions. It is hoped that these developments will usher in a new era of personalized medicine in which an individual's molecular measurements are used to diagnose disease, guide therapy, and perform other tasks more accurately and effectively than is possible using standard approaches. There now exists a vast literature of reported “molecular signatures”. However, despite some notable exceptions, many of these signatures have suffered from limited reproducibility in independent datasets, insufficient sensitivity or specificity to meet clinical needs, or other challenges. In this paper, we discuss the process of molecular signature discovery on the basis of omics data. In particular, we highlight potential pitfalls in the discovery process, as well as strategies that can be used to increase the odds of successful discovery. Despite the difficulties that have plagued the field of molecular signature discovery, we remain optimistic about the potential to harness the vast amounts of available omics data in order to substantially impact clinical practice. The identification of molecular signatures from omics data has many promising applications including omics-based tests for disease-specific diagnostics and accurate phenotype classification. This is however, plagued by issues with data reproducibility – this review discusses the potential pitfalls in the discovery process and strategies for overcoming these issues in order to achieve personalized medicine. PMID:22528809

  1. Analysis of Forgery Attack on One-Time Proxy Signature and the Improvement

    NASA Astrophysics Data System (ADS)

    Wang, Tian-Yin; Wei, Zong-Li

    2016-02-01

    In a recent paper, Yang et al. (Quant. Inf. Process. 13(9), 2007-2016, 2014) analyzed the security of one-time proxy signature scheme Wang and Wei (Quant. Inf. Process. 11(2), 455-463, 2012) and pointed out that it cannot satisfy the security requirements of unforgeability and undeniability because an eavesdropper Eve can forge a valid proxy signature on a message chosen by herself. However, we find that the so-called proxy message-signature pair forged by Eve is issued by the proxy signer in fact, and anybody can obtain it as a requester, which means that the forgery attack is not considered as a successful attack. Therefore, the conclusion that this scheme cannot satisfy the security requirements of proxy signature against forging and denying is not appropriate in this sense. Finally, we study the reason for the misunderstanding and clarify the security requirements for proxy signatures.

  2. Infrared signatures for remote sensing

    SciTech Connect

    McDowell, R.S.; Sharpe, S.W.; Kelly, J.F.

    1994-04-01

    PNL`s capabilities for infrared and near-infrared spectroscopy include tunable-diode-laser (TDL) systems covering 300--3,000 cm{sup {minus}1} at <10-MHz bandwidth; a Bruker Fourier-transform infrared (FTIR) spectrometer for the near- to far-infrared at 50-MHz resolution; and a stable line-tunable, 12-w cw CO{sub 2} laser. PNL also has a beam expansion source with a 12-cm slit, which provides a 3-m effective path for gases at {approximately}10 K, giving a Doppler width of typically 10 MHz; and long-path static gas cells (to 100 m). In applying this equipment to signatures work, the authors emphasize the importance of high spectral resolution for detecting and identifying atmospheric interferences; for identifying the optimum analytical frequencies; for deriving, by spectroscopic analysis, the molecular parameters needed for modeling; and for obtaining data on species and/or bands that are not in existing databases. As an example of such spectroscopy, the authors have assigned and analyzed the C-Cl stretching region of CCl{sub 4} at 770--800 cm{sup {minus}1}. This is an important potential signature species whose IR absorption has remained puzzling because of the natural isotopic mix, extensive hot-band structure, and a Fermi resonance involving a nearby combination band. Instrument development projects include the IR sniffer, a small high-sensitivity, high-discrimination (Doppler-limited) device for fence-line or downwind monitoring that is effective even in regions of atmospheric absorption; preliminary work has achieved sensitivities at the low-ppb level. Other work covers trace species detection with TDLs, and FM-modulated CO{sub 2} laser LIDAR. The authors are planning a field experiment to interrogate the Hanford tank farm for signature species from Rattlesnake Mountain, a standoff of ca. 15 km, to be accompanied by simultaneous ground-truthing at the tanks.

  3. Quantum signatures of chimera states

    NASA Astrophysics Data System (ADS)

    Bastidas, V. M.; Omelchenko, I.; Zakharova, A.; Schöll, E.; Brandes, T.

    2015-12-01

    Chimera states are complex spatiotemporal patterns in networks of identical oscillators, characterized by the coexistence of synchronized and desynchronized dynamics. Here we propose to extend the phenomenon of chimera states to the quantum regime, and uncover intriguing quantum signatures of these states. We calculate the quantum fluctuations about semiclassical trajectories and demonstrate that chimera states in the quantum regime can be characterized by bosonic squeezing, weighted quantum correlations, and measures of mutual information. Our findings reveal the relation of chimera states to quantum information theory, and give promising directions for experimental realization of chimera states in quantum systems.

  4. Spectroscopic signature for ferroelectric ice

    NASA Astrophysics Data System (ADS)

    Wójcik, Marek J.; Gług, Maciej; Boczar, Marek; Boda, Łukasz

    2014-09-01

    Various forms of ice exist within our galaxy. Particularly intriguing type of ice - ‘ferroelectric ice' was discovered experimentally and is stable in temperatures below 72 K. This form of ice can generate enormous electric fields and can play an important role in planetary formation. In this letter we present Car-Parrinello simulation of infrared spectra of ferroelectric ice and compare them with spectra of hexagonal ice. Librational region of the spectra can be treated as spectroscopic signature of ice XI and can be of help to identify ferroelectric ice in the Universe.

  5. Fractal signatures in analogs of interplanetary dust particles

    NASA Astrophysics Data System (ADS)

    Katyal, Nisha; Banerjee, Varsha; Puri, Sanjay

    2014-10-01

    Interplanetary dust particles (IDPs) are an important constituent of the earths stratosphere, interstellar and interplanetary medium, cometary comae and tails, etc. Their physical and optical characteristics are significantly influenced by the morphology of silicate aggregates which form the core in IDPs. In this paper we reinterpret scattering data from laboratory analogs of cosmic silicate aggregates created by Volten et al. (2007) [1] to extract their morphological features. By evaluating the structure factor, we find that the aggregates are mass fractals with a mass fractal dimension dm≃1.75. The same fractal dimension also characterizes clusters obtained from diffusion limited aggregation (DLA). This suggests that the analogs are formed by an irreversible aggregation of stochastically transported silicate particles.

  6. Quantum broadcasting multiple blind signature with constant size

    NASA Astrophysics Data System (ADS)

    Xiao, Min; Li, Zhenli

    2016-06-01

    Using quantum homomorphic signature in quantum network, we propose a quantum broadcasting multiple blind signature scheme. Different from classical signature and current quantum signature schemes, the multi-signature proposed in our scheme is not generated by simply putting the individual signatures together, but by aggregating the individual signatures based on homomorphic property. Therefore, the size of the multi-signature is constant. Furthermore, based on a wide range of investigation for the security of existing quantum signature protocols, our protocol is designed to resist possible forgery attacks against signature and message from the various attack sources and disavowal attacks from participants.

  7. Autophagy-related prognostic signature for breast cancer.

    PubMed

    Gu, Yunyan; Li, Pengfei; Peng, Fuduan; Zhang, Mengmeng; Zhang, Yuanyuan; Liang, Haihai; Zhao, Wenyuan; Qi, Lishuang; Wang, Hongwei; Wang, Chenguang; Guo, Zheng

    2016-03-01

    Autophagy is a process that degrades intracellular constituents, such as long-lived or damaged proteins and organelles, to buffer metabolic stress under starvation conditions. Deregulation of autophagy is involved in the progression of cancer. However, the predictive value of autophagy for breast cancer prognosis remains unclear. First, based on gene expression profiling, we found that autophagy genes were implicated in breast cancer. Then, using the Cox proportional hazard regression model, we detected autophagy prognostic signature for breast cancer in a training dataset. We identified a set of eight autophagy genes (BCL2, BIRC5, EIF4EBP1, ERO1L, FOS, GAPDH, ITPR1 and VEGFA) that were significantly associated with overall survival in breast cancer. The eight autophagy genes were assigned as a autophagy-related prognostic signature for breast cancer. Based on the autophagy-related signature, the training dataset GSE21653 could be classified into high-risk and low-risk subgroups with significantly different survival times (HR = 2.72, 95% CI = (1.91, 3.87); P = 1.37 × 10(-5)). Inactivation of autophagy was associated with shortened survival of breast cancer patients. The prognostic value of the autophagy-related signature was confirmed in the testing dataset GSE3494 (HR = 2.12, 95% CI = (1.48, 3.03); P = 1.65 × 10(-3)) and GSE7390 (HR = 1.76, 95% CI = (1.22, 2.54); P = 9.95 × 10(-4)). Further analysis revealed that the prognostic value of the autophagy signature was independent of known clinical prognostic factors, including age, tumor size, grade, estrogen receptor status, progesterone receptor status, ERBB2 status, lymph node status and TP53 mutation status. Finally, we demonstrated that the autophagy signature could also predict distant metastasis-free survival for breast cancer. PMID:25620657

  8. Update on PIN or Signature

    NASA Astrophysics Data System (ADS)

    Matyas, Vashek

    We promised a year back some data on the experiment that we ran with chip and PIN. If you recall, it was the first phase that we reported on here last year, where we used the University bookstore, and two PIN pads, one with very solid privacy shielding, the other one without any. We ran 17 people through the first one, 15 people through the second one, and we also had the students do, about half of them forging the signature, half of them signing their own signature, on the back of the card that is used for purchasing books, or whatever.We had a second phase of the experiment, after long negotiations, and very complicated logistics, with a supermarket in Brno where we were able to do anything that we wanted through the experiment for five hours on the floor, with only the supermarket manager, the head of security, and the camera operators knowing about the experiment. So the shop assistants, the ground floor security, everybody basically on the floor, did not know about the experiment. That was one of the reasons why the supermarket, or management, agreed to take part, they wanted to control their own internal security procedures.

  9. Theoretical Characterizaiton of Visual Signatures

    NASA Astrophysics Data System (ADS)

    Kashinski, D. O.; Chase, G. M.; di Nallo, O. E.; Scales, A. N.; Vanderley, D. L.; Byrd, E. F. C.

    2015-05-01

    We are investigating the accuracy of theoretical models used to predict the visible, ultraviolet, and infrared spectra, as well as other properties, of product materials ejected from the muzzle of currently fielded systems. Recent advances in solid propellants has made the management of muzzle signature (flash) a principle issue in weapons development across the calibers. A priori prediction of the electromagnetic spectra of formulations will allow researchers to tailor blends that yield desired signatures and determine spectrographic detection ranges. Quantum chemistry methods at various levels of sophistication have been employed to optimize molecular geometries, compute unscaled vibrational frequencies, and determine the optical spectra of specific gas-phase species. Electronic excitations are being computed using Time Dependent Density Functional Theory (TD-DFT). A full statistical analysis and reliability assessment of computational results is currently underway. A comparison of theoretical results to experimental values found in the literature is used to assess any affects of functional choice and basis set on calculation accuracy. The status of this work will be presented at the conference. Work supported by the ARL, DoD HPCMP, and USMA.

  10. Narrow terahertz attenuation signatures in Bacillus thuringiensis.

    PubMed

    Zhang, Weidong; Brown, Elliott R; Viveros, Leamon; Burris, Kellie P; Stewart, C Neal

    2014-10-01

    Terahertz absorption signatures from culture-cultivated Bacillus thuringiensis were measured with a THz photomixing spectrometer operating from 400 to 1200 GHz. We observe two distinct signatures centered at ∼955 and 1015 GHz, and attribute them to the optically coupled particle vibrational resonance (surface phonon-polariton) of Bacillus spores. This demonstrates the potential of the THz attenuation signatures as "fingerprints" for label-free biomolecular detection. PMID:23821459

  11. Cryptanalysis of Quantum Blind Signature Scheme

    NASA Astrophysics Data System (ADS)

    Zuo, Huijuan

    2013-01-01

    In this paper, we study the cryptanalysis of two quantum blind signature schemes and one quantum proxy blind signature protocol. We show that in these protocols the verifier can forge the signature under known message attack. The attack strategies are described in detail respectively. This kind of problem deserves more research attention in the following related study. We further point out that the arbitrator should be involved in the procedure of any dispute and some discussions of these protocols are given.

  12. Imaging radar polarization signatures - Theory and observation

    NASA Technical Reports Server (NTRS)

    Van Zyl, Jakob J.; Zebker, Howard A.; Elachi, Charles

    1987-01-01

    Radar polarimetry theory is reviewed, and comparison between theory and experimental results obtained with an imaging radar polarimeter employing two orthogonally polarized antennas is made. Knowledge of the scattering matrix permits calculation of the scattering cross section of a scatterer for any transmit and receive polarization combination, and a new way of displaying the resulting scattering cross section as a function of polarization is introduced. Examples of polarization signatures are presented for several theoretical models of surface scattering, and these signatures are compared with experimentally measured polarization signatures. The coefficient of variation, derived from the polarization signature, may provide information regarding the amount of variation in scattering properties for a given area.

  13. Secure Obfuscation for Encrypted Group Signatures

    PubMed Central

    Fan, Hongfei; Liu, Qin

    2015-01-01

    In recent years, group signature techniques are widely used in constructing privacy-preserving security schemes for various information systems. However, conventional techniques keep the schemes secure only in normal black-box attack contexts. In other words, these schemes suppose that (the implementation of) the group signature generation algorithm is running in a platform that is perfectly protected from various intrusions and attacks. As a complementary to existing studies, how to generate group signatures securely in a more austere security context, such as a white-box attack context, is studied in this paper. We use obfuscation as an approach to acquire a higher level of security. Concretely, we introduce a special group signature functionality-an encrypted group signature, and then provide an obfuscator for the proposed functionality. A series of new security notions for both the functionality and its obfuscator has been introduced. The most important one is the average-case secure virtual black-box property w.r.t. dependent oracles and restricted dependent oracles which captures the requirement of protecting the output of the proposed obfuscator against collision attacks from group members. The security notions fit for many other specialized obfuscators, such as obfuscators for identity-based signatures, threshold signatures and key-insulated signatures. Finally, the correctness and security of the proposed obfuscator have been proven. Thereby, the obfuscated encrypted group signature functionality can be applied to variants of privacy-preserving security schemes and enhance the security level of these schemes. PMID:26167686

  14. 5 CFR 850.106 - Electronic signatures.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) Non-cryptographic methods, including— (i) Personal Identification Number (PIN) or password; (ii) Smart card; (iii) Digitized signature; or (iv) Biometrics, such as fingerprints, retinal patterns, and...

  15. Input apparatus for dynamic signature verification systems

    DOEpatents

    EerNisse, Errol P.; Land, Cecil E.; Snelling, Jay B.

    1978-01-01

    The disclosure relates to signature verification input apparatus comprising a writing instrument and platen containing piezoelectric transducers which generate signals in response to writing pressures.

  16. Novel Quantum Proxy Signature without Entanglement

    NASA Astrophysics Data System (ADS)

    Xu, Guang-bao

    2015-08-01

    Proxy signature is an important research topic in classic cryptography since it has many application occasions in our real life. But only a few quantum proxy signature schemes have been proposed up to now. In this paper, we propose a quantum proxy signature scheme, which is designed based on quantum one-time pad. Our scheme can be realized easily since it only uses single-particle states. Security analysis shows that it is secure and meets all the properties of a proxy signature, such as verifiability, distinguishability, unforgeability and undeniability.

  17. Recovery of impact signatures in machine structures

    NASA Astrophysics Data System (ADS)

    McCarthy, D. J.; Lyon, R. H.

    1995-09-01

    Reciprocating machines are difficult to diagnose using traditional frequency domain techniques because they generate predominantly transient vibrations which have a broad frequency content. We have found that transient vibrations, like those generated by valve impacts in a reciprocating compressor, are best analysed in the time-domain. Unfortunately, by the time the vibrations reach the surface of the machine where we can measure them non-invasively, reverberation and dispersion have disfigured them so that they look nothing like their originating forces. In order to convert them into a useful form, where they can be characterized in terms of timing and strength on a cycle-by-cycle basis, the vibration signal can be compressed by filtering it with the inverse of the structural transfer function. This is a straightforward process if the exact transfer function is known; however, in practice we expect to have simply a 'typical' transfer function from a nominally identical machine. Additional transfer function variability results from changes in machine operating conditions such as temperature and load. The inverse-filtering process can be made robust to transfer function variability through a combination of cepstral-smoothing and minimum-phase processing. In addition, if a cepstral comb window is incorporated into the signal processing scheme, multiple impact signatures can be removed.

  18. Raman Spectroscopic Signatures of Echovirus 1 Uncoating

    PubMed Central

    Ruokola, Päivi; Dadu, Elina; Kazmertsuk, Artur; Häkkänen, Heikki; Marjomäki, Varpu

    2014-01-01

    ABSTRACT In recent decades, Raman spectroscopy has entered the biological and medical fields. It enables nondestructive analysis of structural details at the molecular level and has been used to study viruses and their constituents. Here, we used Raman spectroscopy to study echovirus 1 (EV1), a small, nonenveloped human pathogen, in two different uncoating states induced by heat treatments. Raman signals of capsid proteins and RNA genome were observed from the intact virus, the uncoating intermediate, and disrupted virions. Transmission electron microscopy data revealed general structural changes between the studied particles. Compared to spectral characteristics of proteins in the intact virion, those of the proteins of the heat-treated particles indicated reduced α-helix content with respect to β-sheets and coil structures. Changes observed in tryptophan and tyrosine signals suggest an increasingly hydrophilic environment around these residues. RNA signals revealed a change in the environment of the genome and in its conformation. The ionized-carbonyl vibrations showed small changes between the intact virion and the uncoating intermediate, which points to cleavage of salt bridges in the protein structure during the uncoating process. In conclusion, our data reveal distinguishable Raman signatures of the intact, intermediate, and disrupted EV1 particles. These changes indicate structural, chemical, and solute-solvent alterations in the genome and in the capsid proteins and lay the essential groundwork for investigating the uncoating of EV1 and related viruses in real time. IMPORTANCE In order to combat virus infection, we need to know the details of virus uncoating. We present here the novel Raman signatures for opened and intact echovirus 1. This gives hope that the signatures may be used in the near future to evaluate the ambient conditions in endosomes leading to virus uncoating using, e.g., coherent anti-Stokes Raman spectroscopy (CARS) imaging. These

  19. Multiparametric Geophysical Signature of Vulcanian Explosions

    NASA Astrophysics Data System (ADS)

    Gottsmann, J.; de Angelis, S.; Fournier, N.; van Camp, M. J.; Sacks, S. I.; Linde, A. T.; Ripepe, M.

    2010-12-01

    Extrusion of viscous magma leading to lava dome-formation is a common phenomenon at arc volcanoes recently demonstrated at Mount St. Helens (USA), Chaiten (Chile), and SoufriËre Hills Volcano (British West Indies). The growth of lava domes is frequently accompanied by vigorous eruptions, commonly referred to as Vulcanian-style, characterized by sequences of short-lived (tens of seconds to tens of minutes) explosive pulses, reflecting the violent explosive nature of arc volcanism. Vulcanian eruptions represent a significant hazard, and an understanding of their dynamics is vital for risk mitigation. While eruption parameters have been mostly constrained from observational evidence, as well as from petrological, theoretical, and experimental studies, our understanding on the physics of the subsurface processes leading to Vulcanian eruptions is incomplete. We present and interpret a unique set of multi-parameter geophysical data gathered during two Vulcanian eruptions in July and December, 2008 at SoufriËre Hills Volcano from seismic, geodetic, infrasound, barometric, and gravimetric instrumentation. These events document the spectrum of Vulcanian eruptions in terms of their explosivity and nature of erupted products. Our analysis documents a pronounced difference in the geophysical signature of the two events associated with priming timescales and eruption triggering suggesting distinct differences in the mechanics involved. The July eruption has a signature related to shallow conduit dynamics including gradual system destabilisation, syn-eruptive decompression of the conduit by magma fragmentation, conduit emptying and expulsion of juvenile pumice. In contrast, sudden pressurisation of the entire plumbing system including the magma chambers resulted in dome carapace failure, a violent cannon-like explosion, propagation of a shock wave and pronounced ballistic ejection of dome fragments. We demonstrate that with lead times of between one and six minutes to the

  20. Somatic ERCC2 mutations are associated with a distinct genomic signature in urothelial tumors.

    PubMed

    Kim, Jaegil; Mouw, Kent W; Polak, Paz; Braunstein, Lior Z; Kamburov, Atanas; Tiao, Grace; Kwiatkowski, David J; Rosenberg, Jonathan E; Van Allen, Eliezer M; D'Andrea, Alan D; Getz, Gad

    2016-06-01

    Alterations in DNA repair pathways are common in tumors and can result in characteristic mutational signatures; however, a specific mutational signature associated with somatic alterations in the nucleotide- excision repair (NER) pathway has not yet been identified. Here we examine the mutational processes operating in urothelial cancer, a tumor type in which the core NER gene ERCC2 is significantly mutated. Analysis of three independent urothelial tumor cohorts demonstrates a strong association between somatic ERCC2 mutations and the activity of a mutational signature characterized by a broad spectrum of base changes. In addition, we note an association between the activity of this signature and smoking that is independent of ERCC2 mutation status, providing genomic evidence of tobacco-related mutagenesis in urothelial cancer. Together, these analyses identify an NER-related mutational signature and highlight the related roles of DNA damage and subsequent DNA repair in shaping tumor mutational landscape. PMID:27111033

  1. NPOESS Interface Data Processing Segment Architecture and Software

    NASA Astrophysics Data System (ADS)

    Turek, S.; Souza, K. G.; Fox, C. A.; Grant, K. D.

    2004-12-01

    The National Oceanic and Atmospheric Administration (NOAA), Department of Defense (DoD), and National Aeronautics and Space Administration (NASA) are jointly acquiring the next-generation weather and environmental satellite system; the National Polar-orbiting Operational Environmental Satellite System (NPOESS). NPOESS is an estimated \\$6.5 billion program replacing the current Polar-orbiting Operational Environmental Satellites (POES) managed by NOAA and the Defense Meteorological Satellite Program (DMSP) managed by the DoD. The NPOESS satellites carry a suite of sensors that collect meteorological, oceanographic, climatological, and solar-geophysical observations of the earth, atmosphere, and space. The ground data processing segment for NPOESS is the Interface Data Processing Segment (IDPS). The IDPS processes NPOESS satellite data to provide weather, oceanographic, and environmental data products to NOAA and DoD processing centers and field terminals operated by the United States government. This paper describes Raytheon's high performance computer and software architecture for the NPOESS IDPS. NOAA, the DoD, and NASA selected this architecture after a 2.5-year Program Definition and Risk Reduction (PDRR) competition. The PDRR phase concluded in August of 2002, and has been followed by the NPOESS Preparatory Project (NPP) phase. The NPP satellite, scheduled to launch in late 2006, will provide risk reduction for the future NPOESS satellites, and will enable data continuity between the current EOS missions and NPOESS. Efforts within the PDRR and NPP phases consist of: requirements definition and flowdown from system to segment to subsystem, Object-Oriented (OO) software design, software code development, science to operational code conversion, integration and qualification testing. The NPOESS phase, which supports a constellation of three satellites, will also consist of this same lifecycle during the 2005 through 2009 timeframe, with operations and support

  2. Metabolic Signatures of Bacterial Vaginosis

    PubMed Central

    Morgan, Martin T.; Fiedler, Tina L.; Djukovic, Danijel; Hoffman, Noah G.; Raftery, Daniel; Marrazzo, Jeanne M.

    2015-01-01

    ABSTRACT Bacterial vaginosis (BV) is characterized by shifts in the vaginal microbiota from Lactobacillus dominant to a microbiota with diverse anaerobic bacteria. Few studies have linked specific metabolites with bacteria found in the human vagina. Here, we report dramatic differences in metabolite compositions and concentrations associated with BV using a global metabolomics approach. We further validated important metabolites using samples from a second cohort of women and a different platform to measure metabolites. In the primary study, we compared metabolite profiles in cervicovaginal lavage fluid from 40 women with BV and 20 women without BV. Vaginal bacterial representation was determined using broad-range PCR with pyrosequencing and concentrations of bacteria by quantitative PCR. We detected 279 named biochemicals; levels of 62% of metabolites were significantly different in women with BV. Unsupervised clustering of metabolites separated women with and without BV. Women with BV have metabolite profiles marked by lower concentrations of amino acids and dipeptides, concomitant with higher levels of amino acid catabolites and polyamines. Higher levels of the signaling eicosanoid 12-hydroxyeicosatetraenoic acid (12-HETE), a biomarker for inflammation, were noted in BV. Lactobacillus crispatus and Lactobacillus jensenii exhibited similar metabolite correlation patterns, which were distinct from correlation patterns exhibited by BV-associated bacteria. Several metabolites were significantly associated with clinical signs and symptoms (Amsel criteria) used to diagnose BV, and no metabolite was associated with all four clinical criteria. BV has strong metabolic signatures across multiple metabolic pathways, and these signatures are associated with the presence and concentrations of particular bacteria. PMID:25873373

  3. RELATIVISTIC MERGERS OF SUPERMASSIVE BLACK HOLES AND THEIR ELECTROMAGNETIC SIGNATURES

    SciTech Connect

    Bode, Tanja; Haas, Roland; Laguna, Pablo; Shoemaker, Deirdre; Bogdanovic, Tamara

    2010-06-01

    Coincident detections of electromagnetic (EM) and gravitational wave (GW) signatures from coalescence events of supermassive black holes (SMBHs) are the next observational grand challenge. Such detections will provide the means to study cosmological evolution and accretion processes associated with these gargantuan compact objects. More generally, the observations will enable testing general relativity in the strong, nonlinear regime and will provide independent cosmological measurements to high precision. Understanding the conditions under which coincidences of EM and GW signatures arise during SMBH mergers is therefore of paramount importance. As an essential step toward this goal, we present results from the first fully general relativistic, hydrodynamical study of the late inspiral and merger of equal-mass, spinning SMBH binaries in a gas cloud. We find that variable EM signatures correlated with GWs can arise in merging systems as a consequence of shocks and accretion combined with the effect of relativistic beaming. The most striking EM variability is observed for systems where spins are aligned with the orbital axis and where orbiting black holes form a stable set of density wakes, but all systems exhibit some characteristic signatures that can be utilized in searches for EM counterparts. In the case of the most massive binaries observable by the Laser Interferometer Space Antenna, calculated luminosities imply that they may be identified by EM searches to z {approx} 1, while lower mass systems and binaries immersed in low density ambient gas can only be detected in the local universe.

  4. Polarimetric Signatures of Sea Ice. Part 1; Theoretical Model

    NASA Technical Reports Server (NTRS)

    Nghiem, S. V.; Kwok, R.; Yueh, S. H.; Drinkwater, M. R.

    1995-01-01

    Physical, structural, and electromagnetic properties and interrelating processes in sea ice are used to develop a composite model for polarimetric backscattering signatures of sea ice. Physical properties of sea ice constituents such as ice, brine, air, and salt are presented in terms of their effects on electromagnetic wave interactions. Sea ice structure and geometry of scatterers are related to wave propagation, attenuation, and scattering. Temperature and salinity, which are determining factors for the thermodynamic phase distribution in sea ice, are consistently used to derive both effective permittivities and polarimetric scattering coefficients. Polarimetric signatures of sea ice depend on crystal sizes and brine volumes, which are affected by ice growth rates. Desalination by brine expulsion, drainage, or other mechanisms modifies wave penetration and scattering. Sea ice signatures are further complicated by surface conditions such as rough interfaces, hummocks, snow cover, brine skim, or slush layer. Based on the same set of geophysical parameters characterizing sea ice, a composite model is developed to calculate effective permittivities and backscattering covariance matrices at microwave frequencies for interpretation of sea ice polarimetric signatures.

  5. Polarimetric signatures of sea ice. 1: Theoretical model

    NASA Technical Reports Server (NTRS)

    Nghiem, S. V.; Kwok, R.; Yueh, S. H.; Drinkwater, M. R.

    1995-01-01

    Physical, structral, and electromagnetic properties and interrelating processes in sea ice are used to develop a composite model for polarimetric backscattering signatures of sea ice. Physical properties of sea ice constituents such as ice, brine, air, and salt are presented in terms of their effects on electromagnetic wave interactions. Sea ice structure and geometry of scatterers are related to wave propagation, attenuation, and scattering. Temperature and salinity, which are determining factors for the thermodynamic phase distribution in sea ice, are consistently used to derive both effective permittivities and polarimetric scattering coefficients. Polarmetric signatures of sea ice depend on crystal sizes and brine volumes, which are affected by ice growth rates. Desalination by brine expulsion, drainage, or other mechanisms modifies wave penetration and scattering. Sea ice signatures are further complicated by surface conditions such as rough interfaces, hummocks, snow cover, brine skim, or slush layer. Based on the same set of geophysical parameters characterizing sea ice, a composite model is developed to calculate effective permittivities and backscattering covariance matrices at microwave frequencies to interpretation of sea ice polarimetric signatures.

  6. Discovery of signature genes in gastric cancer associated with prognosis.

    PubMed

    Zhao, X; Cai, H; Wang, X; Ma, L

    2016-01-01

    Gene expression profiles of gastric cancer (GC) were analyzed with bioinformatics tools to identify signature genes associated with prognosis. Four gene expression data sets (accession number: GSE2685, GSE30727, GSE38932 and GSE26253) were downloaded from Gene Expression Omnibus. Differentially expressed genes (DEGs) were screened out using significance analysis of microarrays (SAM) algorithm. P-value 1 were set as the threshold. A co-expression network was constructed for the GC-related genes with package WGCNA of R. Modules were disclosed with WGCNA algorithm. Survival-related signature genes were screened out via COX single-variable regression.A total of 3210 GC-related genes were identified from the 3 data sets. Significantly enriched GO biological process terms included cell death, cell proliferation, apoptosis, response to hormone and phosphorylation. Pathways like viral carcinogenesis, metabolism, EBV viral infection, and PI3K-AKT signaling pathway were significantly over-represented in the DEGs. A gene co-expression network including 2414 genes was constructed, from which 7 modules were revealed. A total of 17 genes were identified as signature genes, such as DAB2, ALDH2, CD58, CITED2, BNIP3L, SLC43A2, FAU and COL5A1.Many signature genes associated with prognosis of GC were identified in present study, some of which have been implicated in the pathogenesis of GC. These findings could not only improve the knowledge about GC, but also provide clues for clinical treatments. PMID:26774142

  7. Combustion sources of particles. 1. Health relevance and source signatures.

    PubMed

    Morawska, Lidia; Zhang, Junfeng Jim

    2002-12-01

    Combustion processes result in generation of a large number of particle and gaseous products that create health and environmental risks. Of particular importance are the very small particles that are emitted in large quantities from all the combustion sources, and that have been shown to be potentially more significant in terms of their impact on health than larger particles. To control and mitigate the particles with a view of health and environmental risk reduction, a good understanding is necessary of the relative and absolute contribution from the emission sources to the airborne concentrations. This understanding could only be achieved by developing source signature libraries through direct emission measurements from the sources on one hand, and by measuring particle concentrations in the air, and apportioning them to the specific local and distant sources using the signatures, on the other hand. This paper is a review of particle characteristics that are used as source signatures as well as their general advantages and limitations. The second part of the paper reviews source signatures of the most common combustion pollution sources. PMID:12492164

  8. 21 CFR 11.200 - Electronic signature components and controls.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Electronic signature components and controls. 11... SERVICES GENERAL ELECTRONIC RECORDS; ELECTRONIC SIGNATURES Electronic Signatures § 11.200 Electronic signature components and controls. (a) Electronic signatures that are not based upon biometrics shall:...

  9. 21 CFR 11.200 - Electronic signature components and controls.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Electronic signature components and controls. 11... SERVICES GENERAL ELECTRONIC RECORDS; ELECTRONIC SIGNATURES Electronic Signatures § 11.200 Electronic signature components and controls. (a) Electronic signatures that are not based upon biometrics shall:...

  10. 7 CFR 718.9 - Signature requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 7 2012-01-01 2012-01-01 false Signature requirements. 718.9 Section 718.9 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF... MULTIPLE PROGRAMS General Provisions § 718.9 Signature requirements. (a) When a program authorized by...

  11. 7 CFR 718.9 - Signature requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 7 2014-01-01 2014-01-01 false Signature requirements. 718.9 Section 718.9 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF... MULTIPLE PROGRAMS General Provisions § 718.9 Signature requirements. (a) When a program authorized by...

  12. 7 CFR 718.9 - Signature requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Signature requirements. 718.9 Section 718.9 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF... MULTIPLE PROGRAMS General Provisions § 718.9 Signature requirements. (a) When a program authorized by...

  13. 5 CFR 850.106 - Electronic signatures.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 2 2013-01-01 2013-01-01 false Electronic signatures. 850.106 Section... (CONTINUED) RETIREMENT SYSTEMS MODERNIZATION General Provisions § 850.106 Electronic signatures. (a) Subject to any provisions prescribed by the Director under § 850.104— (1) An electronic communication may...

  14. 5 CFR 850.106 - Electronic signatures.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Electronic signatures. 850.106 Section... (CONTINUED) RETIREMENT SYSTEMS MODERNIZATION General Provisions § 850.106 Electronic signatures. (a) Subject to any provisions prescribed by the Director under § 850.104— (1) An electronic communication may...

  15. 5 CFR 850.106 - Electronic signatures.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false Electronic signatures. 850.106 Section... (CONTINUED) RETIREMENT SYSTEMS MODERNIZATION General Provisions § 850.106 Electronic signatures. (a) Subject to any provisions prescribed by the Director under § 850.104— (1) An electronic communication may...

  16. Does Social Work Have a Signature Pedagogy?

    ERIC Educational Resources Information Center

    Earls Larrison, Tara; Korr, Wynne S.

    2013-01-01

    This article contributes to discourse on signature pedagogy by reconceptualizing how our pedagogies are understood and defined for social work education. We critique the view that field education is social work's signature pedagogy and consider what pedagogies are distinct about the teaching and learning of social work. Using Shulman's…

  17. 5 CFR 850.106 - Electronic signatures.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 2 2012-01-01 2012-01-01 false Electronic signatures. 850.106 Section 850.106 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) RETIREMENT SYSTEMS MODERNIZATION General Provisions § 850.106 Electronic signatures. (a) Subject to any provisions prescribed by...

  18. A Real Quantum Designated Verifier Signature Scheme

    NASA Astrophysics Data System (ADS)

    Shi, Wei-Min; Zhou, Yi-Hua; Yang, Yu-Guang

    2015-09-01

    The effectiveness of most quantum signature schemes reported in the literature can be verified by a designated person, however, those quantum signature schemes aren't the real traditional designated verifier signature schemes, because the designated person hasn't the capability to efficiently simulate a signature which is indistinguishable from a signer, which cannot satisfy the requirements in some special environments such as E-voting, call for tenders and software licensing. For solving this problem, a real quantum designated verifier signature scheme is proposed in this paper. According to the property of unitary transformation and quantum one-way function, only a verifier designated by a signer can verify the "validity of a signature" and the designated verifier cannot prove to a third party that the signature was produced by the signer or by himself through a transcript simulation algorithm. Moreover, the quantum key distribution and quantum encryption algorithm guarantee the unconditional security of this scheme. Analysis results show that this new scheme satisfies the main security requirements of designated verifier signature scheme and the major attack strategies.

  19. 17 CFR 12.12 - Signature.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Signature. 12.12 Section 12.12 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION RULES RELATING TO REPARATIONS General Information and Preliminary Consideration of Pleadings § 12.12 Signature. (a) By whom....

  20. Redactable signatures for signed CDA Documents.

    PubMed

    Wu, Zhen-Yu; Hsueh, Chih-Wen; Tsai, Cheng-Yu; Lai, Feipei; Lee, Hung-Chang; Chung, Yufang

    2012-06-01

    The Clinical Document Architecture, introduced by Health Level Seven, is a XML-based standard intending to specify the encoding, structure, and semantics of clinical documents for exchange. Since the clinical document is in XML form, its authenticity and integrity could be guaranteed by the use of the XML signature published by W3C. While a clinical document wants to conceal some personal or private information, the document needs to be redacted. It makes the signed signature of the original clinical document not be verified. The redactable signature is thus proposed to enable verification for the redacted document. Only a little research does the implementation of the redactable signature, and there still not exists an appropriate scheme for the clinical document. This paper will investigate the existing web-technologies and find a compact and applicable model to implement a suitable redactable signature for the clinical document viewer. PMID:21181244

  1. Security Weaknesses in Arbitrated Quantum Signature Protocols

    NASA Astrophysics Data System (ADS)

    Liu, Feng; Zhang, Kejia; Cao, Tianqing

    2014-01-01

    Arbitrated quantum signature (AQS) is a cryptographic scenario in which the sender (signer), Alice, generates the signature of a message and then a receiver (verifier), Bob, can verify the signature with the help of a trusted arbitrator, Trent. In this paper, we point out there exist some security weaknesses in two AQS protocols. Our analysis shows Alice can successfully disavow any of her signatures by a simple attack in the first protocol. Furthermore, we study the security weaknesses of the second protocol from the aspects of forgery and disavowal. Some potential improvements of this kind of protocols are given. We also design a new method to authenticate a signature or a message, which makes AQS protocols immune to Alice's disavowal attack and Bob's forgery attack effectively.

  2. Nucleon-decay-like signatures of hylogenesis

    NASA Astrophysics Data System (ADS)

    Demidov, S. V.; Gorbunov, D. S.

    2016-02-01

    We consider nucleon-decay-like signatures of hylogenesis, a variant of the antibaryonic dark matter model. For the interaction between visible and dark matter sectors through the neutron portal, we calculate the rates of dark matter scatterings off a neutron which mimic neutron-decay processes n →ν γ and n →ν e+e- with richer kinematics. We obtain bounds on the model parameters from nonobservation of the neutron decays by applying the kinematical cuts adopted in the experimental analyses. The bounds are generally (much) weaker than those coming from the recently performed study of events with a single jet of high transverse momentum and missing energy observed at the LHC. Then we suggest several new nucleon-decay-like processes with two mesons in the final state and estimate (accounting for the LHC constraints) the lower limits on the nucleon lifetime with respect to these channels. The obtained values appear to be promising for probing the antibaryonic dark matter at future underground experiments like HyperK and DUNE.

  3. Slowflow Signatures of Sustainable Water Resources

    NASA Astrophysics Data System (ADS)

    Schwartz, S. S.; Smith, B.

    2012-12-01

    Land transformation changes the sustainability of water resources by (a) altering the vegetation, impervious landcover, and drainage of the land surface hydrology system; (b) increasing withdrawals from surface and groundwater systems to support human water use; and (c) re-engineering the water budget through water and wastewater infrastructure that conveys interbasin water transfers and modifies both recharge and subsurface drainage. Slowflow derived from observed streamflow integrates watershed-scale hydrologic forcings and cumulative landscape changes. Multiple slowflow indices derived from USGS streamflow records are used to frame an endpoint mixing model of dominant hydrologic processes and human hydrologic alteration. Multimetric slowflow fingerprints can support more refined process-based inferences, distinguishing, e.g., changes in hydrologic response - (runoff and recharge) from changes in hydraulic response (effective aquifer drainage) in regional streamflow analysis. Examples drawn from USGS streamflow records along the urban-rural landuse gradient in the watersheds of the Baltimore Ecosystem Study (an NSF Urban Long Term Ecological Research site in the Baltimore Metropolitan area) and piedmont Hydroclimatic Data Network (HCDN) basins in the Chesapeake Bay watershed, are used to illustrate multimetric fingerprinting of slowflow response. Within the inherent limits of equifinality in observed streamflow response, multimetric slowflow analysis can refine the signature and attribution of hydroclimatic variability and human hydrologic alteration inferred from regional streamflow information.

  4. NIST bullet signature measurement system for RM (Reference Material) 8240 standard bullets.

    PubMed

    Ma, Li; Song, John; Whitenton, Eric; Zheng, Alan; Vorburger, Theodore; Zhou, Jack

    2004-07-01

    A bullet signature measurement system based on a stylus instrument was developed at the National Institute of Standards and Technology (NIST) for the signature measurements of NIST RM (Reference Material) 8240 standard bullets. The standard bullets are developed as a reference standard for bullet signature measurements and are aimed to support the recently established National Integrated Ballistics Information Network (NIBIN) by the Bureau of Alcohol, Tobacco and Firearms (ATF) and the Federal Bureau of Investigation (FBI). The RM bullets are designed as both a virtual and a physical bullet signature standard. The virtual standard is a set of six digitized bullet signatures originally profiled from six master bullets fired at ATF and FBI using six different guns. By using the virtual signature standard to control the tool path on a numerically controlled diamond turning machine at NIST, 40 RM bullets were produced. In this paper, a comparison parameter and an algorithm using auto-and cross-correlation functions are described for qualifying the bullet signature differences between the RM bullets and the virtual bullet signature standard. When two compared signatures are exactly the same (point by point), their cross-correlation function (CCF) value will be equal to 100%. The measurement system setup, measurement program, and initial measurement results are discussed. Initial measurement results for the 40 standard bullets, each measured at six land impressions, show that the CCF values for the 240 signature measurements are higher than 95%, with most of them even higher than 99%. These results demonstrate the high reproducibility for both the manufacturing process and the measurement system for the NIST RM 8240 standard bullets. PMID:15317178

  5. 21 CFR 11.200 - Electronic signature components and controls.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... signature components and controls. (a) Electronic signatures that are not based upon biometrics shall: (1... signatures based upon biometrics shall be designed to ensure that they cannot be used by anyone other...

  6. 21 CFR 11.200 - Electronic signature components and controls.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... signature components and controls. (a) Electronic signatures that are not based upon biometrics shall: (1... signatures based upon biometrics shall be designed to ensure that they cannot be used by anyone other...

  7. 21 CFR 11.200 - Electronic signature components and controls.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... signature components and controls. (a) Electronic signatures that are not based upon biometrics shall: (1... signatures based upon biometrics shall be designed to ensure that they cannot be used by anyone other...

  8. Estimating the pen trajectories of static signatures using hidden Markov models.

    PubMed

    Nel, Emli-Mari; du Preez, Johan A; Herbst, B M

    2005-11-01

    Static signatures originate as handwritten images on documents and by definition do not contain any dynamic information. This lack of information makes static signature verification systems significantly less reliable than their dynamic counterparts. This study involves extracting dynamic information from static images, specifically the pen trajectory while the signature was created. We assume that a dynamic version of the static image is available (typically obtained during an earlier registration process). We then derive a hidden Markov model from the static image and match it to the dynamic version of the image. This match results in the estimated pen trajectory of the static image. PMID:16285373

  9. Infrared ship signature analysis and optimisation

    NASA Astrophysics Data System (ADS)

    Neele, Filip

    2005-05-01

    The last decade has seen an increase in the awareness of the infrared signature of naval ships. New ship designs show that infrared signature reduction measures are being incorporated, such as exhaust gas cooling systems, relocation of the exhausts and surface cooling systems. Hull and superstructure are cooled with dedicated spray systems, in addition to special paint systems that are being developed for optimum stealth. This paper presents a method to develop requirements for the emissivity of a ship's coating that reduces the contrast of the ship against its background in the wavelength band or bands of threat sensors. As this contrast strongly depends on the atmospheric environment, these requirements must follow from a detailed analysis of the infrared signature of the ship in its expected areas of operation. Weather statistics for a large number of areas have been collected to produce a series of 'standard environments'. These environments have been used to demonstrate the method of specifying coating emissivity requirements. Results are presented to show that the optimised coatings reduce the temperature contrast. The use of the standard environments yields a complete, yet concise, description of the signature of the ship over its areas of operation. The signature results illustrate the strong dependence of the infrared signature on the atmospheric environment and can be used to identify those conditions where signature reduction is most effective in reducing the ship's susceptibility to detection by IR sensors.

  10. Molecular signatures of major depression.

    PubMed

    Cai, Na; Chang, Simon; Li, Yihan; Li, Qibin; Hu, Jingchu; Liang, Jieqin; Song, Li; Kretzschmar, Warren; Gan, Xiangchao; Nicod, Jerome; Rivera, Margarita; Deng, Hong; Du, Bo; Li, Keqing; Sang, Wenhu; Gao, Jingfang; Gao, Shugui; Ha, Baowei; Ho, Hung-Yao; Hu, Chunmei; Hu, Jian; Hu, Zhenfei; Huang, Guoping; Jiang, Guoqing; Jiang, Tao; Jin, Wei; Li, Gongying; Li, Kan; Li, Yi; Li, Yingrui; Li, Youhui; Lin, Yu-Ting; Liu, Lanfen; Liu, Tiebang; Liu, Ying; Liu, Yuan; Lu, Yao; Lv, Luxian; Meng, Huaqing; Qian, Puyi; Sang, Hong; Shen, Jianhua; Shi, Jianguo; Sun, Jing; Tao, Ming; Wang, Gang; Wang, Guangbiao; Wang, Jian; Wang, Linmao; Wang, Xueyi; Wang, Xumei; Yang, Huanming; Yang, Lijun; Yin, Ye; Zhang, Jinbei; Zhang, Kerang; Sun, Ning; Zhang, Wei; Zhang, Xiuqing; Zhang, Zhen; Zhong, Hui; Breen, Gerome; Wang, Jun; Marchini, Jonathan; Chen, Yiping; Xu, Qi; Xu, Xun; Mott, Richard; Huang, Guo-Jen; Kendler, Kenneth; Flint, Jonathan

    2015-05-01

    Adversity, particularly in early life, can cause illness. Clues to the responsible mechanisms may lie with the discovery of molecular signatures of stress, some of which include alterations to an individual's somatic genome. Here, using genome sequences from 11,670 women, we observed a highly significant association between a stress-related disease, major depression, and the amount of mtDNA (p = 9.00 × 10(-42), odds ratio 1.33 [95% confidence interval [CI] = 1.29-1.37]) and telomere length (p = 2.84 × 10(-14), odds ratio 0.85 [95% CI = 0.81-0.89]). While both telomere length and mtDNA amount were associated with adverse life events, conditional regression analyses showed the molecular changes were contingent on the depressed state. We tested this hypothesis with experiments in mice, demonstrating that stress causes both molecular changes, which are partly reversible and can be elicited by the administration of corticosterone. Together, these results demonstrate that changes in the amount of mtDNA and telomere length are consequences of stress and entering a depressed state. These findings identify increased amounts of mtDNA as a molecular marker of MD and have important implications for understanding how stress causes the disease. PMID:25913401

  11. Multifractal signatures of infectious diseases.

    PubMed

    Holdsworth, Amber M; Kevlahan, Nicholas K-R; Earn, David J D

    2012-09-01

    Incidence of infection time-series data for the childhood diseases measles, chicken pox, rubella and whooping cough are described in the language of multifractals. We explore the potential of using the wavelet transform maximum modulus (WTMM) method to characterize the multiscale structure of the observed time series and of simulated data generated by the stochastic susceptible-exposed-infectious-recovered (SEIR) epidemic model. The singularity spectra of the observed time series suggest that each disease is characterized by a unique multifractal signature, which distinguishes that particular disease from the others. The wavelet scaling functions confirm that the time series of measles, rubella and whooping cough are clearly multifractal, while chicken pox has a more monofractal structure in time. The stochastic SEIR epidemic model is unable to reproduce the qualitative singularity structure of the reported incidence data: it is too smooth and does not appear to have a multifractal singularity structure. The precise reasons for the failure of the SEIR epidemic model to reproduce the correct multiscale structure of the reported incidence data remain unclear. PMID:22442094

  12. Chemical Signatures in Dwarf Galaxies

    NASA Astrophysics Data System (ADS)

    Venn, Kim A.; Hill, Vanessa M.

    2008-12-01

    Chemical signatures in dwarf galaxies describe the examination of specific elemental abundance ratios to investigate the formation and evolution of dwarf galaxies, particularly when compared with the variety of stellar populations in the Galaxy. Abundance ratios can come from HII region emission lines, planetary nebulae, or supernova remnants, but mostly they come from stars. Since stars can live a very long time, for example, a 0.8 MSun star born at the time of the Big Bang would only now be ascending the red giant branch, and, if, for the most part, its quiescent main sequence lifetime had been uneventful, then it is possible that the surface chemistry of stars actually still resembles their natal chemistry. Detailed abundances of stars in dwarf galaxies can be used to reconstruct their chemical evolution, which we now find to be distinct from any other component of the Galaxy, questioning the assertion that dwarf galaxies like these built up the Galaxy. Potential solutions to reconciling dwarf galaxy abundances and Galaxy formation models include the timescale for significant merging and the possibility for uncovering different stellar populations in the new ultra-faint dwarfs.

  13. Imaging spectral signature satellite instrument for the real-time identification of ground scenes with a dedicated spectral signature

    NASA Astrophysics Data System (ADS)

    Kantojärvi, Uula; Saari, Heikki; Viherkanto, Kai; Herrala, Esko; Harnisch, Bernd

    2007-05-01

    With hyperspectral pushbroom imaging spectrometers on Earth observation satellites it is possible to detect and identify dedicated ground pixels by their spectral signature. Conventional time consuming on-ground processing performs this selection by processing the measured hyperspectral data cube of the image. The Imaging Spectral Signature Instrument (ISSI) concept combines an optical on-board processing of the hyperspectral data cube with a thresholding algorithm, to identify pixels with a pre-defined and programmable spectral signature, such as water, forest and minerals, in the ground swath. The Imaging Spectral Signature Instrument consists of an imaging telescope, which images an object line on the entrance slit of a first imaging spectrometer, which disperses each pixel of the object line into its spectral content and images the hyperspectral image on the spatial light modulator. This spatial light modulator will be programmed with a spatial transmission or reflection behavior, which is constant along the spatial pixels and along the spectral pixels identical to a filter vector that corresponds to the spectral signature of the searched specific feature. A second inverted spectrometer reimages the by the first spectrometer dispersed and by the spatial light modulator transmitted or reflected flux into a line of pixels. In case the spectral content of the ground scene is identical to the searched signature, the flux traversing or reflecting the spatial light modulator will be maximum. The related pixel can be identified in the final image as a high signal by a threshold discriminator. A component test setup consists of an imaging lens, two Imspector™ spectrographs, a spatial light modulator, which is a programmable transmissible liquid crystal display and a CCD sensor as a detector. A mathematical model was developed for the instrument and its performance was evaluated in order to compare different concept variations. All components were measured and

  14. Improved Quantum Signature Scheme with Weak Arbitrator

    NASA Astrophysics Data System (ADS)

    Su, Qi; Li, Wen-Min

    2013-09-01

    In this paper, we find a man-in-the-middle attack on the quantum signature scheme with a weak arbitrator (Luo et al., Int. J. Theor. Phys., 51:2135, 2012). In that scheme, the authors proposed a quantum signature based on quantum one way function which contains both verifying the signer phase and verifying the signed message phase. However, after our analysis we will show that Eve can adopt different strategies in respective phases to forge the signature without being detected. Then we present an improved scheme to increase the security.

  15. Arbitrated quantum signature with an untrusted arbitrator

    NASA Astrophysics Data System (ADS)

    Yang, Yu-Guang; Zhou, Zheng; Teng, Yi-Wei; Wen, Qiao-Yan

    2011-02-01

    In an arbitrated signature scheme, all communications involve a so called arbitrator who has access to the contents of the messages. The security of most arbitrated signature schemes depends heavily on the trustworthiness of the arbitrators. In this paper we show how to construct an arbitrated quantum signature protocol of classical messages with an untrusted arbitrator. Its security is analyzed and it is proved to be secure even if the arbitrator is compromised. In addition, the proposed protocol does not require a direct quantum link between any two communicating users, which is an appealing advantage in the implementation of a practical quantum distributed communication network.

  16. Timing signatures of large scale solar eruptions

    NASA Astrophysics Data System (ADS)

    Balasubramaniam, K. S.; Hock-Mysliwiec, Rachel; Henry, Timothy; Kirk, Michael S.

    2016-05-01

    We examine the timing signatures of large solar eruptions resulting in flares, CMEs and Solar Energetic Particle events. We probe solar active regions from the chromosphere through the corona, using data from space and ground-based observations, including ISOON, SDO, GONG, and GOES. Our studies include a number of flares and CMEs of mostly the M- and X-strengths as categorized by GOES. We find that the chromospheric signatures of these large eruptions occur 5-30 minutes in advance of coronal high temperature signatures. These timing measurements are then used as inputs to models and reconstruct the eruptive nature of these systems, and explore their utility in forecasts.

  17. Physics of the inner heliosphere: Mechanisms, models and observational signatures

    NASA Technical Reports Server (NTRS)

    Withbroe, George L.

    1987-01-01

    Selected problems concerned with the important physical processes that occur in the corona and solar wind acceleration region, particularly time dependent phenomena were studied. Both the physics of the phenomena and the resultant effects on observational signatures, particularly spectroscopic signatures were also studied. Phenomena under study include: wave motions, particularly Alfven and fast mode waves; the formation of standing shocks in the inner heliosphere as a result of momentum and/or heat addition to the wind; and coronal transient phenomena where momentum and/or heat are deposited in the corona to produce transient plasma heating and/or mass ejection. The development of theoretical models for the inner heliosphere, the theoretical investigation of spectroscopic plasma diagnostics for this region, and the analysis of existing skylab and other relevant data are also included.

  18. Identification of human motion signature using airborne radar data

    NASA Astrophysics Data System (ADS)

    McDonald, Michael; Damini, Anthony

    2013-09-01

    Data containing the radar signature of amoving person on the groundwere collected at ranges of up to 30 kmfroma moving airborne platform using the DRDC Ottawa X-bandWideband Experimental Airborne Radar (XWEAR). The human target radar echo returns were found to possess a characteristic amplitude modulated (AM) and frequency modulated (FM) signature which could be usefully characterized in terms of conventional AM and FM modulation parameters. Human detection performance after space time adaptive processing is frequently limited by false alarms arising from incomplete cancellation of large radar cross-section discretes during the whitening step. However, the clutter discretes possess different modulation characteristics from the human targets discussed above. The ability of pattern classification techniques to use this parameter measurement space to distinguish between human targets and clutter discretes is explored and preliminary results presented.

  19. A signature correlation study of ground target VHF/UHF ISAR imagery

    NASA Astrophysics Data System (ADS)

    Gatesman, Andrew J.; Beaudoin, Christopher J.; Giles, Robert H.; Kersey, William T.; Waldman, Jerry; Carter, Steve; Nixon, William E.

    2003-09-01

    VV and HH-polarized radar signatures of several ground targets were acquired in the VHF/UHF band (171-342 MHz) by using 1/35th scale models and an indoor radar range operating from 6 to 12 GHz. Data were processed into medianized radar cross sections as well as focused, ISAR imagery. Measurement validation was confirmed by comparing the radar cross section of a test object with a method of moments radar cross section prediction code. The signatures of several vehicles from three vehicle classes (tanks, trunks, and TELs) were measured and a signature cross-correlation study was performed. The VHF/UHF band is currently being exploited for its foliage penetration ability, however, the coarse image resolution which results from the relatively long radar wavelengths suggests a more challenging target recognition problem. One of the study's goals was to determine the amount of unique signature content in VHF/UHF ISAR imagery of military ground vehicles. Open-field signatures are compared with each other as well as with simplified shapes of similar size. Signatures were also acquired on one vehicle in a variety of configurations to determine the impact of monitor target variations on the signature content at these frequencies.

  20. The Application of Spatial Signature Analysis to Electrical Test Data: Validation Study

    SciTech Connect

    Gleason, S.S.; Karnowski, T.P.; Lakhani, F.; Tobin, K.W.

    1999-03-15

    This paper presents the results of the Spatial Signature Analysis (SSA) Electrical-test (e-test) validation study that was conducted between February and June, 1998. SSA is an automated procedure developed by researchers at the Oak Ridge National Laboratory to address the issue of intelligent data reduction while providing feedback on current manufacturing processes. SSA was initially developed to automate the analysis of optical defect data. Optical defects can form groups, or clusters, which may have a distinct shape. These patterns can reveal information about the manufacturing process. Optical defect SSA uses image processing algorithms and a classifier system to interpret and identify these patterns, or signatures. SSA has been extended to analyze and interpret electrical test data. The algorithms used for optical defect SSA have been adapted and applied to e-test binmaps. An image of the binmap is created, and features such as geometric and invariant moments are extracted and presented to a pair-wise, fuzzy, k-NN classifier. The classifier itself was prepared by manually training, which consists of storing example signatures of interest in a library, then executing an automated process which treats the examples as prototype signatures. The training process includes a procedure for automatically determining which features are most relevant to each class. The evaluation was performed by installing the SSA software as a batch process at three SEMATECH member company sites. Feedback from member company representatives was incorporated and classifiers were built to automatically assign labels to the binmap signatures. The three sites produced memory devices (DRAM) and microprocessors in a mature process fabrication environment. For all of these products, 5,620 signatures that encompassed approximately 552 wafers were human-classified and analyzed. The performance of the SSA E-test system indicates that the approach was successful in reliably classifying binmap

  1. ACCRETING CIRCUMPLANETARY DISKS: OBSERVATIONAL SIGNATURES

    SciTech Connect

    Zhu, Zhaohuan

    2015-01-20

    I calculate the spectral energy distributions of accreting circumplanetary disks using atmospheric radiative transfer models. Circumplanetary disks only accreting at 10{sup –10} M {sub ☉} yr{sup –1} around a 1 M{sub J} planet can be brighter than the planet itself. A moderately accreting circumplanetary disk ( M-dot ∼10{sup −8} M{sub ⊙} yr{sup −1}; enough to form a 10 M{sub J} planet within 1 Myr) around a 1 M{sub J} planet has a maximum temperature of ∼2000 K, and at near-infrared wavelengths (J, H, K bands), this disk is as bright as a late-M-type brown dwarf or a 10 M{sub J} planet with a ''hot start''. To use direct imaging to find the accretion disks around low-mass planets (e.g., 1 M{sub J} ) and distinguish them from brown dwarfs or hot high-mass planets, it is crucial to obtain photometry at mid-infrared bands (L', M, N bands) because the emission from circumplanetary disks falls off more slowly toward longer wavelengths than those of brown dwarfs or planets. If young planets have strong magnetic fields (≳100 G), fields may truncate slowly accreting circumplanetary disks ( M-dot ≲10{sup −9} M{sub ⊙} yr{sup −1}) and lead to magnetospheric accretion, which can provide additional accretion signatures, such as UV/optical excess from the accretion shock and line emission.

  2. Experimental demonstration of photonic quantum digital signatures

    NASA Astrophysics Data System (ADS)

    Collins, Robert J.; Clarke, Patrick J.; Dunjko, Vedran; Andersson, Erika; Jeffers, John; Buller, Gerald S.

    2012-09-01

    Digital signature schemes are often used in interconnected computer networks to verify the origin and authenticity of messages. Current classical digital signature schemes based on so-called "one-way functions" rely on computational complexity to provide security over sufficiently long timescales. However, there are currently no mathematical proofs that such functions will always be computationally complex. Quantum digital signatures offers a means of confirming both origin and authenticity of a message with security verified by information theoretical limits. The message cannot be forged or repudiated. We have constructed, tested and analyzed the security of what is, to the best of our knowledge, the first example of an experimental quantum digital signature system.

  3. 15 CFR 908.16 - Signature.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... SUBMITTING REPORTS ON WEATHER MODIFICATION ACTIVITIES § 908.16 Signature. All reports filed with the National... or intending to conduct the weather modification activities referred to therein by such...

  4. 15 CFR 908.16 - Signature.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... SUBMITTING REPORTS ON WEATHER MODIFICATION ACTIVITIES § 908.16 Signature. All reports filed with the National... or intending to conduct the weather modification activities referred to therein by such...

  5. 15 CFR 908.16 - Signature.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... SUBMITTING REPORTS ON WEATHER MODIFICATION ACTIVITIES § 908.16 Signature. All reports filed with the National... or intending to conduct the weather modification activities referred to therein by such...

  6. Biomarker Signature Discovery from Mass Spectrometry Data.

    PubMed

    Kong, Ao; Gupta, Chinmaya; Ferrari, Mauro; Agostini, Marco; Bedin, Chiara; Bouamrani, Ali; Tasciotti, Ennio; Azencott, Robert

    2014-01-01

    Mass spectrometry based high throughput proteomics are used for protein analysis and clinical diagnosis. Many machine learning methods have been used to construct classifiers based on mass spectrometry data, for discrimination between cancer stages. However, the classifiers generated by machine learning such as SVM techniques typically lack biological interpretability. We present an innovative technique for automated discovery of signatures optimized to characterize various cancer stages. We validate our signature discovery algorithm on one new colorectal cancer MALDI-TOF data set, and two well-known ovarian cancer SELDI-TOF data sets. In all of these cases, our signature based classifiers performed either better or at least as well as four benchmark machine learning algorithms including SVM and KNN. Moreover, our optimized signatures automatically select smaller sets of key biomarkers than the black-boxes generated by machine learning, and are much easier to interpret. PMID:26356346

  7. Microbial Signatures In Sulfate-Rich Playas

    NASA Astrophysics Data System (ADS)

    Glamoclija, M.; Steele, A.; Starke, V.; Zeidan, M.; Potochniak, S.; Sirisena, K.; Widanagamage, I. H.

    2016-05-01

    Microbes that live in playas represent organisms able to cope with transient environments, ranging from fresh to hyper-saline water settings and from wet to dry. We will try to identify mineral and chemical signatures of their presence.

  8. 15 CFR 908.16 - Signature.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... SUBMITTING REPORTS ON WEATHER MODIFICATION ACTIVITIES § 908.16 Signature. All reports filed with the National... or intending to conduct the weather modification activities referred to therein by such...

  9. Secure quantum signatures using insecure quantum channels

    NASA Astrophysics Data System (ADS)

    Amiri, Ryan; Wallden, Petros; Kent, Adrian; Andersson, Erika

    2016-03-01

    Digital signatures are widely used in modern communication to guarantee authenticity and transferability of messages. The security of currently used classical schemes relies on computational assumptions. We present a quantum signature scheme that does not require trusted quantum channels. We prove that it is unconditionally secure against the most general coherent attacks, and show that it requires the transmission of significantly fewer quantum states than previous schemes. We also show that the quantum channel noise threshold for our scheme is less strict than for distilling a secure key using quantum key distribution. This shows that "direct" quantum signature schemes can be preferable to signature schemes relying on secret shared keys generated using quantum key distribution.

  10. Spectral Signatures of Saccade Target Selection.

    PubMed

    Carl, Christine; Hipp, Joerg F; König, Peter; Engel, Andreas K

    2016-01-01

    Action generation relies on a widely distributed network of brain areas. However, little is known about the spatiotemporal dynamics of neuronal activity in the network that gives rise to voluntary action in humans. Here, we used magnetoencephalography (MEG) and source analysis (n = 15, 7 female subjects) to investigate the spectral signatures of human cortical networks engaged in active and intrinsically motivated viewing behavior. We compared neuronal activity of externally cued saccades with saccades to freely chosen targets. For planning and execution of both saccade types, we found an increase in gamma band (~64-128 Hz) activity and a concurrent decrease in beta band (~12-32 Hz) activity in saccadic control areas, including the intraparietal sulcus and the frontal eye fields. Guided compared to voluntary actions were accompanied by stronger transient increases in the gamma and low frequency (<16 Hz) range immediately following the instructional cue. In contrast, action selection between competing alternatives was reflected by stronger sustained fronto-parietal gamma increases that occurred later in time and persisted until movement execution. This sustained enhancement for free target selection was accompanied by a spatially widespread reduction of lower frequency power (~8-45 Hz) in parietal and extrastriate areas. Our results suggest that neuronal population activity in the gamma frequency band in a distributed network of fronto-parietal areas reflects the intrinsically driven process of selection among competing behavioral alternatives. PMID:25690830

  11. Timecourse of neural signatures of object recognition.

    PubMed

    Johnson, Jeffrey S; Olshausen, Bruno A

    2003-01-01

    How long does it take for the human visual system to recognize objects? This issue is important for understanding visual cortical function as it places constraints on models of the information processing underlying recognition. We designed a series of event-related potential (ERP) experiments to measure the timecourse of electrophysiological correlates of object recognition. We find two distinct types of components in the ERP recorded during categorization of natural images. One is an early presentation-locked signal arising around 135 ms that is present when there are low-level feature differences between images. The other is a later, recognition-related component arising between 150-300 ms. Unlike the early component, the latency of the later component covaries with the subsequent reaction time. In contrast to previous studies suggesting that the early, presentation-locked component of neural activity is correlated to recognition, these results imply that the neural signatures of recognition have a substantially later and variable time of onset. PMID:14507255

  12. New signatures of flavor violating Higgs couplings

    NASA Astrophysics Data System (ADS)

    Buschmann, Malte; Kopp, Joachim; Liu, Jia; Wang, Xiao-Ping

    2016-06-01

    We explore several novel LHC signatures arising from quark or lepton flavor violating couplings in the Higgs sector, and we constrain such couplings using LHC data. Since the largest signals are possible in channels involving top quarks or tau leptons, we consider in particular the following flavor violating processes: (1) pp → thh (top plus di-Higgs final state) arising from a dimension six coupling of up-type quarks to three insertions of the Higgs field. We develop a search strategy for this final state and demonstrate that detection is possible at the high luminosity LHC if flavor violating top-up-Higgs couplings are not too far below the current limit. (2) pp → tH 0, where H 0 is the heavy neutral CP-even Higgs boson in a two Higgs doublet model (2HDM). We consider the decay channels H 0 → tu, WW, ZZ, hh and use existing LHC data to constrain the first three of them. For the fourth, we adapt our search for the thh final state, and we demonstrate that in large regions of the parameter space, it is superior to other searches, including searches for flavor violating top quark decays ( t → hq). (3) H 0 → τ μ, again in the context of a 2HDM. This channel is particularly well motivated by the recent CMS excess in h → τ μ, and we use the data from this search to constrain the properties of H 0.

  13. Photon signature analysis using template matching

    NASA Astrophysics Data System (ADS)

    Bradley, D. A.; Hashim, S.; Saripan, M. I.; Wells, K.; Dunn, W. L.

    2011-10-01

    We describe an approach to detect improvised explosive devices (IEDs) by using a template matching procedure. This approach relies on the signature due to backstreaming γ photons from various targets. In this work we have simulated cylindrical targets of aluminum, iron, copper, water and ammonium nitrate (nitrogen-rich fertilizer). We simulate 3.5 MeV source photons distributed on a plane inside a shielded area using Monte Carlo N-Particle (MCNP TM) code version 5 (V5). The 3.5 MeV source gamma rays yield 511 keV peaks due to pair production and scattered gamma rays. In this work, we simulate capture of those photons that backstream, after impinging on the target element, toward a NaI detector. The captured backstreamed photons are expected to produce a unique spectrum that will become part of a simple signal processing recognition system based on the template matching method. Different elements were simulated using different sets of random numbers in the Monte Carlo simulation. To date, the sum of absolute differences (SAD) method has been used to match the template. In the examples investigated, template matching was found to detect all elements correctly.

  14. Distinguishing Biotic from Abiotic Phosphate Oxygen Isotopic Signatures

    NASA Astrophysics Data System (ADS)

    Blake, R.; Moyer, C.; Colman, A.; Liang, Y.; Dogru, D.

    2006-05-01

    On earth, phosphate has a strong biological oxygen isotope signature due to its concentration and intense cycling by living organisms as an essential nutrient. Phosphate does not undergo oxygen isotope exchange with water at low temperature without enzymatic catalysis, making the oxygen isotope ratio (18O/16O) of phosphate, δ18OP, an attractive biosignature in the search for early and extraterrestrial life. Recent laboratory and field studies have demonstrated that the δ18OP value of dissolved inorganic phosphate (PO4) records specific microbial activity and enzymatic reaction pathways in both laboratory cultures and natural waters/sediments (Blake et al., 2005; Colman et al 2005; Liang and Blake, 2005). Phosphate oxygen isotope biosignatures may be distinguished from abiotic signatures by: (1) evaluating the degree of temperature-dependent PO4-water oxygen isotope exchange in aqueous systems and deviation from equilibrium; and (2) evolution from an abiotic P reservoir signature towards a biotic P reservoir signature. Important abiotic processes potentially affecting phosphate δ18OP values include dissolution/precipitation, adsorption/desorption, recrystallization of PO4 mineral phases, diagenesis and metamorphism. For most of these processes, the recording, retention and alteration of δ18OP biosignatures have not been evaluated. Deep-sea hydrothermal vent fields are an ideal system in which to study the preservation and alteration of δ18OP biosignatures, as well as potential look-alikes produced by heat-promoted PO4 -water oxygen isotope exchange. Results from recent studies of δ18OP biosignatures in hydrothermal deposits near 9 and 21 degrees N. EPR and at Loihi seamount will be presented.

  15. Signature-based store checking buffer

    DOEpatents

    Sridharan, Vilas; Gurumurthi, Sudhanva

    2015-06-02

    A system and method for optimizing redundant output verification, are provided. A hardware-based store fingerprint buffer receives multiple instances of output from multiple instances of computation. The store fingerprint buffer generates a signature from the content included in the multiple instances of output. When a barrier is reached, the store fingerprint buffer uses the signature to verify the content is error-free.

  16. Quantum blind signature with an offline repository

    NASA Astrophysics Data System (ADS)

    Ribeiro, J.; Souto, A.; Mateus, P.

    2015-04-01

    We propose a quantum blind signature scheme that achieves perfect security under the assumption of an honest offline repository. The security of the protocol also relies on perfect private quantum channels, which are achievable using quantum one-time pads with keys shared via a quantum key distribution (QKD) protocol. The proposed approach ensures that signatures cannot be copied and that the sender must compromise to a single message, which are important advantages over classical protocols for certain applications.

  17. Signature scheme based on bilinear pairs

    NASA Astrophysics Data System (ADS)

    Tong, Rui Y.; Geng, Yong J.

    2013-03-01

    An identity-based signature scheme is proposed by using bilinear pairs technology. The scheme uses user's identity information as public key such as email address, IP address, telephone number so that it erases the cost of forming and managing public key infrastructure and avoids the problem of user private generating center generating forgery signature by using CL-PKC framework to generate user's private key.

  18. Research Plan for Fire Signatures and Detection

    NASA Technical Reports Server (NTRS)

    2004-01-01

    Viewgraphs on the prevention, suppression, and detection of fires aboard a spacecraft is presented. The topics include: 1) Fire Prevention, Detection, and Suppression Sub-Element Products; 2) FPDS Organizing Questions; 3) FPDS Organizing Questions; 4) Signatures, Sensors, and Simulations; 5) Quantification of Fire and Pre-Fire Signatures; 6) Smoke; 7) DAFT Hardware; 8) Additional Benefits of DAFT; 9) Development and Characterization of Sensors 10) Simulation of the Transport of Smoke and Fire Precursors; and 11) FPDS Organizing Questions.

  19. Kinematics of signature writing in healthy aging.

    PubMed

    Caligiuri, Michael P; Kim, Chi; Landy, Kelly M

    2014-07-01

    Forensic document examiners (FDE) called upon to distinguish a genuine from a forged signature of an elderly person are often required to consider the question of age-related deterioration and whether the available exemplars reliably capture the natural effects of aging of the original writer. An understanding of the statistical relationship between advanced age and handwriting movements can reduce the uncertainty that may exist in an examiner's approach to questioned signatures formed by elderly writers. The primary purpose of this study was to systematically examine age-related changes in signature kinematics in healthy writers. Forty-two healthy subjects between the ages of 60-91 years participated in this study. Signatures were recorded using a digitizing tablet, and commercial software was used to examine the temporal and spatial stroke kinematics and pen pressure. Results indicated that vertical stroke duration and dysfluency increased with age, whereas vertical stroke amplitude and velocity decreased with age. Pen pressure decreased with age. We found that a linear model characterized the best-fit relationship between advanced age and handwriting movement parameters for signature formation. Male writers exhibited stronger age effects than female writers, especially for pen pressure and stroke dysfluency. The present study contributes to an understanding of how advanced age alters signature formation in otherwise healthy adults. PMID:24673648

  20. Assessing the Quality of Bioforensic Signatures

    SciTech Connect

    Sego, Landon H.; Holmes, Aimee E.; Gosink, Luke J.; Webb-Robertson, Bobbie-Jo M.; Kreuzer, Helen W.; Anderson, Richard M.; Brothers, Alan J.; Corley, Courtney D.; Tardiff, Mark F.

    2013-06-04

    We present a mathematical framework for assessing the quality of signature systems in terms of fidelity, cost, risk, and utility—a method we refer to as Signature Quality Metrics (SQM). We demonstrate the SQM approach by assessing the quality of a signature system designed to predict the culture medium used to grow a microorganism. The system consists of four chemical assays designed to identify various ingredients that could be used to produce the culture medium. The analytical measurements resulting from any combination of these four assays can be used in a Bayesian network to predict the probabilities that the microorganism was grown using one of eleven culture media. We evaluated fifteen combinations of the signature system by removing one or more of the assays from the Bayes network. We demonstrated that SQM can be used to distinguish between the various combinations in terms of attributes of interest. The approach assisted in clearly identifying assays that were least informative, largely in part because they only could discriminate between very few culture media, and in particular, culture media that are rarely used. There are limitations associated with the data that were used to train and test the signature system. Consequently, our intent is not to draw formal conclusions regarding this particular bioforensic system, but rather to illustrate an analytical approach that could be useful in comparing one signature system to another.

  1. Chemical and Physical Signatures for Microbial Forensics

    SciTech Connect

    Cliff, John B.; Kreuzer, Helen W.; Ehrhardt, Christopher J.; Wunschel, David S.

    2012-01-03

    Chemical and physical signatures for microbial forensics John Cliff and Helen Kreuzer-Martin, eds. Humana Press Chapter 1. Introduction: Review of history and statement of need. Randy Murch, Virginia Tech Chapter 2. The Microbe: Structure, morphology, and physiology of the microbe as they relate to potential signatures of growth conditions. Joany Jackman, Johns Hopkins University Chapter 3. Science for Forensics: Special considerations for the forensic arena - quality control, sample integrity, etc. Mark Wilson (retired FBI): Western Carolina University Chapter 4. Physical signatures: Light and electron microscopy, atomic force microscopy, gravimetry etc. Joseph Michael, Sandia National Laboratory Chapter 5. Lipids: FAME, PLFA, steroids, LPS, etc. James Robertson, Federal Bureau of Investigation Chapter 6. Carbohydrates: Cell wall components, cytoplasm components, methods Alvin Fox, University of South Carolina School of Medicine David Wunschel, Pacific Northwest National Laboratory Chapter 7. Peptides: Peptides, proteins, lipoproteins David Wunschel, Pacific Northwest National Laboratory Chapter 8. Elemental content: CNOHPS (treated in passing), metals, prospective cell types John Cliff, International Atomic Energy Agency Chapter 9. Isotopic signatures: Stable isotopes C,N,H,O,S, 14C dating, potential for heavy elements. Helen Kreuzer-Martin, Pacific Northwest National Laboratory Michaele Kashgarian, Lawrence Livermore National Laboratory Chapter 10. Extracellular signatures: Cellular debris, heme, agar, headspace, spent media, etc Karen Wahl, Pacific Northwest National Laboratory Chapter 11. Data Reduction and Integrated Microbial Forensics: Statistical concepts, parametric and multivariate statistics, integrating signatures Kristin Jarman, Pacific Northwest National Laboratory

  2. Phenotypic robustness and the assortativity signature of human transcription factor networks.

    PubMed

    Pechenick, Dov A; Payne, Joshua L; Moore, Jason H

    2014-08-01

    Many developmental, physiological, and behavioral processes depend on the precise expression of genes in space and time. Such spatiotemporal gene expression phenotypes arise from the binding of sequence-specific transcription factors (TFs) to DNA, and from the regulation of nearby genes that such binding causes. These nearby genes may themselves encode TFs, giving rise to a transcription factor network (TFN), wherein nodes represent TFs and directed edges denote regulatory interactions between TFs. Computational studies have linked several topological properties of TFNs - such as their degree distribution - with the robustness of a TFN's gene expression phenotype to genetic and environmental perturbation. Another important topological property is assortativity, which measures the tendency of nodes with similar numbers of edges to connect. In directed networks, assortativity comprises four distinct components that collectively form an assortativity signature. We know very little about how a TFN's assortativity signature affects the robustness of its gene expression phenotype to perturbation. While recent theoretical results suggest that increasing one specific component of a TFN's assortativity signature leads to increased phenotypic robustness, the biological context of this finding is currently limited because the assortativity signatures of real-world TFNs have not been characterized. It is therefore unclear whether these earlier theoretical findings are biologically relevant. Moreover, it is not known how the other three components of the assortativity signature contribute to the phenotypic robustness of TFNs. Here, we use publicly available DNaseI-seq data to measure the assortativity signatures of genome-wide TFNs in 41 distinct human cell and tissue types. We find that all TFNs share a common assortativity signature and that this signature confers phenotypic robustness to model TFNs. Lastly, we determine the extent to which each of the four components of the

  3. MMW, IR, and SAM signature collection

    NASA Astrophysics Data System (ADS)

    Reichstetter, Fred; Ward, Mary E.

    2002-08-01

    During the development of smart weapon's seeker/sensors, it is imperative to collect high quality signatures of the targets the system is intended to engage. These signatures are used to support algorithm development so the system can find and engage the targets of interest in the specific kill area on the target. Englin AFB FL is the AF development center for munitions; and in support of the development effort, the 46th Test Wing (46 TW) has initiated significant improvements in collection capabilities for signatures in the MMW, Infrared and Seismic, Acoustic and Magnetic (SAM) spectrum. Additionally, the Joint Munitions Test and Evaluation program office maintains a fleet of foreign ground vehicle targets used for such signature collection including items such as tanks, SCUD missile launchers, air defense units such as SA-06, SA-8, SA-13, and associated ground support trucks and general purpose vehicles. The major test facility includes a 300 ft tower used for mounting the instrumentation suite that currently includes, 10, 35 and 94 GHz MMW and 2-5(mu) and 8-12(mu) IR instrumentation systems. This facility has undergone major improvements in terms of background signature reduction, construction of a high bay building to house the turntable on which the targets are mounted, and an additional in- ground stationary turntable primarily for IR signature collection. Our experience using this facility to collect signatures for the smart weapons development community has confirmed a significant improvement in quality and efficiency. The need for the stationary turntable signature collection capability was driven by the requirements of the IR community who are interested in collecting signatures in clutter. This tends to be contrary to the MMW community that desires minimum background clutter. The resulting location, adjacent to the MMW tower, allows variations in the type and amount of clutter background that could be incorporated and also provides maximum utilization of

  4. 47 CFR 54.419 - Validity of electronic signatures.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 3 2013-10-01 2013-10-01 false Validity of electronic signatures. 54.419... electronic signatures. (a) For the purposes of this subpart, an electronic signature, defined by the Electronic Signatures in Global and National Commerce Act, as an electronic sound, symbol, or...

  5. 47 CFR 54.419 - Validity of electronic signatures.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 3 2014-10-01 2014-10-01 false Validity of electronic signatures. 54.419... electronic signatures. (a) For the purposes of this subpart, an electronic signature, defined by the Electronic Signatures in Global and National Commerce Act, as an electronic sound, symbol, or...

  6. 47 CFR 54.419 - Validity of electronic signatures.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 3 2012-10-01 2012-10-01 false Validity of electronic signatures. 54.419... electronic signatures. (a) For the purposes of this subpart, an electronic signature, defined by the Electronic Signatures in Global and National Commerce Act, as an electronic sound, symbol, or...

  7. 47 CFR 54.680 - Validity of electronic signatures.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 3 2014-10-01 2014-10-01 false Validity of electronic signatures. 54.680... Validity of electronic signatures. (a) For the purposes of this subpart, an electronic signature (defined by the Electronic Signatures in Global and National Commerce Act, as an electronic sound, symbol,...

  8. 47 CFR 54.680 - Validity of electronic signatures.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 3 2013-10-01 2013-10-01 false Validity of electronic signatures. 54.680... Validity of electronic signatures. (a) For the purposes of this subpart, an electronic signature (defined by the Electronic Signatures in Global and National Commerce Act, as an electronic sound, symbol,...

  9. Electronic Signatures: They're Legal, Now What?

    ERIC Educational Resources Information Center

    Broderick, Martha A.; Gibson, Virginia R.; Tarasewich, Peter

    2001-01-01

    In the United States, electronic signatures recently became as legally binding as printed signatures. Reviews the status of electronic signatures in the United States, and compares it to work done by the United Nations. Summarizes the technology that can be used to implement electronic signatures. Discusses problems and open issues surrounding the…

  10. Human relevance of an in vitro gene signature in HaCaT for skin sensitization.

    PubMed

    van der Veen, Jochem W; Hodemaekers, Henny; Reus, Astrid A; Maas, Wilfred J M; van Loveren, Henk; Ezendam, Janine

    2015-02-01

    The skin sensitizing potential of chemicals is mainly assessed using animal methods, such as the murine local lymph node assay. Recently, an in vitro assay based on a gene expression signature in the HaCaT keratinocyte cell line was proposed as an alternative to these animal methods. Here, the human relevance of this gene signature is assessed through exposure of freshly isolated human skin to the chemical allergens dinitrochlorobenzene (DNCB) and diphenylcyclopropenone (DCP). In human skin, the gene signature shows similar direction of regulation as was previously observed in vitro, suggesting that the molecular processes that drive expression of these genes are similar between the HaCaT cell line and freshly isolated skin, providing evidence for the human relevance of the gene signature. PMID:25236440

  11. Signature verification by only single genuine sample in offline and online systems

    NASA Astrophysics Data System (ADS)

    Adamski, Marcin; Saeed, Khalid

    2016-06-01

    The paper presents innovatory methods and algorithms with experimental results on signature verification. It is mainly focused on applications where there is only one reference signature available for comparison. Such restriction is often present in practice and requires selection of specific methods. In this context, both offline and online approaches are investigated. In offline approach, binary image of the signature is initially thinned to obtain a one pixel-wide line. Then, a sampling technique is applied in order to form the signature feature vector. The identification and verification processes are based on comparing the reference feature vector with the questioned samples using Shape Context algorithm. In the case of online data, the system makes use of dynamic information such as trajectory, pen pressure, pen azimuth and pen altitude collected at the time of signing. After further preprocessing, these functional features are verified by means of Dynamic Time Warping method.

  12. The research of a new test method about dynamic target infrared spectral signature

    NASA Astrophysics Data System (ADS)

    Wu, Jiang-hui; Gao, Jiao-bo; Chen, Qing; Luo, Yan-ling; Li, Jiang-jun; Gao, Ze-dong; Wang, Nan; Gao, Meng

    2014-11-01

    The research on infrared spectral target signature shows great military importance in the domain of IR detection Recognition, IRCM, IR image guide and ir stealth etc. The measurements of infrared spectral of tactical targets have been a direct but effective technique in providing signatures for both analysis and simulation to missile seeker designers for many years. In order to deal with the problem of dynamic target infrared spectral signature, this paper presents a new method for acquiring and testing ir spectral radiation signatures of dynamic objects, which is based on an IR imager guiding the target and acquiring the scene at the same time, a FOV chopping scan infrared spectral radiometer alternatively testing the target and its background around ir spectral signature.ir imager and spectral radiometer have the same optical axis. The raw test data was processed according to a new deal with method. Principles and data processing methods were described in detail, test error also analyzed. Field test results showed that the method described in the above is right; the test error was reduced smaller, and can better satisfy the needs of acquiring dynamic target ir spectral signature.

  13. Applying dynamic methods in off-line signature recognition

    NASA Astrophysics Data System (ADS)

    Igarza, Juan Jose; Hernaez, Inmaculada; Goirizelaia, Inaki; Espinosa, Koldo

    2004-08-01

    In this paper we present the work developed on off-line signature verification using Hidden Markov Models (HMM). HMM is a well-known technique used by other biometric features, for instance, in speaker recognition and dynamic or on-line signature verification. Our goal here is to extend Left-to-Right (LR)-HMM to the field of static or off-line signature processing using results provided by image connectivity analysis. The chain encoding of perimeter points for each blob obtained by this analysis is an ordered set of points in the space, clockwise around the perimeter of the blob. We discuss two different ways of generating the models depending on the way the blobs obtained from the connectivity analysis are ordered. In the first proposed method, blobs are ordered according to their perimeter length. In the second proposal, blobs are ordered in their natural reading order, i.e. from the top to the bottom and left to right. Finally, two LR-HMM models are trained using the parameters obtained by the mentioned techniques. Verification results of the two techniques are compared and some improvements are proposed.

  14. Hyperspectral imagery for observing spectral signature change in Aspergillus flavus

    NASA Astrophysics Data System (ADS)

    DiCrispino, Kevin; Yao, Haibo; Hruska, Zuzana; Brabham, Kori; Lewis, David; Beach, Jim; Brown, Robert L.; Cleveland, Thomas E.

    2005-11-01

    Aflatoxin contaminated corn is dangerous for domestic animals when used as feed and cause liver cancer when consumed by human beings. Therefore, the ability to detect A. flavus and its toxic metabolite, aflatoxin, is important. The objective of this study is to measure A. flavus growth using hyperspectral technology and develop spectral signatures for A. flavus. Based on the research group's previous experiments using hyperspectral imaging techniques, it has been confirmed that the spectral signature of A. flavus is unique and readily identifiable against any background or surrounding surface and among other fungal strains. This study focused on observing changes in the A. flavus spectral signature over an eight-day growth period. The study used a visible-near-infrared hyperspectral image system for data acquisition. This image system uses focal plane pushbroom scanning for high spatial and high spectral resolution imaging. Procedures previously developed by the research group were used for image calibration and image processing. The results showed that while A. flavus gradually progressed along the experiment timeline, the day-to-day surface reflectance of A. flavus displayed significant difference in discreet regions of the wavelength spectrum. External disturbance due to environmental changes also altered the growth and subsequently changed the reflectance patterns of A. flavus.

  15. A cancer-specific transcriptional signature in human neoplasia

    PubMed Central

    Nicassio, Francesco; Bianchi, Fabrizio; Capra, Maria; Vecchi, Manuela; Confalonieri, Stefano; Bianchi, Marco; Pajalunga, Deborah; Crescenzi, Marco; Bonapace, Ian Marc; Di Fiore, Pier Paolo

    2005-01-01

    The molecular anatomy of cancer cells is being explored through unbiased approaches aimed at the identification of cancer-specific transcriptional signatures. An alternative biased approach is exploitation of molecular tools capable of inducing cellular transformation. Transcriptional signatures thus identified can be readily validated in real cancers and more easily reverse-engineered into signaling pathways, given preexisting molecular knowledge. We exploited the ability of the adenovirus early region 1 A protein (E1A) oncogene to force the reentry into the cell cycle of terminally differentiated cells in order to identify and characterize genes whose expression is upregulated in this process. A subset of these genes was activated through a retinoblastoma protein/E2 viral promoter required factor–independent (pRb/E2F-independent) mechanism and was overexpressed in a fraction of human cancers. Furthermore, this overexpression correlated with tumor progression in colon cancer, and 2 of these genes predicted unfavorable prognosis in breast cancer. A proof of principle biological validation was performed on one of the genes of the signature, skeletal muscle cell reentry-induced (SKIN) gene, a previously undescribed gene. SKIN was found overexpressed in some primary tumors and tumor cell lines and was amplified in a fraction of colon adenocarcinomas. Furthermore, knockdown of SKIN caused selective growth suppression in overexpressing tumor cell lines but not in tumor lines expressing physiological levels of the transcript. Thus, SKIN is a candidate oncogene in human cancer. PMID:16224537

  16. Untraceable partially blind signature based on DLOG problem.

    PubMed

    Huang, Zheng; Chen, Ke-fei; Kou, Wei-dong

    2004-01-01

    This paper proposes a new untraceable Partially Blind Signature scheme which is a cross between the traditional signature scheme and the blind signature scheme. In this proposed scheme, the message M that the signer signed can be divided into two parts. The first part can be known to the signer (like that in the traditional signature scheme) while the other part cannot be known to the signer (like that in the blind signature scheme). After having signed M, the signer cannot determine if he has made the signature of M except through the part that he knows. We draw ideas from Brands' "Restricted Blind Signature" to solve the Untraceable Partially Blind Signature problem. Our scheme is a probabilistic signature scheme and the security of our Untraceable Partially Blind Signature scheme relies on the difficulty of computing discrete logarithm. PMID:14663850

  17. Microwave-Spectral Signatures Would Reveal Concealed Objects

    NASA Technical Reports Server (NTRS)

    Arndt, G.; Ngo, P.; Carl, J. R.; Byerly, K.; Stolarcyzk, L.

    2004-01-01

    A proposed technique for locating concealed objects (especially small antipersonnel land mines) involves the acquisition and processing of spectral signatures over broad microwave frequency bands. This technique was conceived to overcome the weaknesses of older narrow- band electromagnetic techniques like ground-probing radar and low-frequency electromagnetic induction. Ground-probing radar is susceptible to false detections and/or interference caused by rocks, roots, air pockets, soil inhomogeneities, ice, liquid water, and miscellaneous buried objects other than those sought. Moreover, if the radar frequency happens to be one for which the permittivity of a sought object matches the permittivity of the surrounding soil or there is an unfavorable complex-amplitude addition of the radar reflection at the receiver, then the object is not detected. Low-frequency electromagnetic induction works well for detecting metallic objects, but the amounts of metal in plastic mines are often too small to be detectable. The potential advantage of the proposed technique arises from the fact that wideband spectral signatures generally contain more relevant information than do narrow-band signals. Consequently, spectral signatures could be used to make better decisions regarding whether concealed objects are present and whether they are the ones sought. In some cases, spectral signatures could provide information on the depths, sizes, shapes, and compositions of objects. An apparatus to implement the proposed technique (see Figure 1) could be assembled from equipment already in common use. Typically, such an apparatus would include a radio-frequency (RF) transmitter/receiver, a broad-band microwave antenna, and a fast personal computer loaded with appropriate software. In operation, the counter would be turned on, the antenna would be aimed at the ground or other mass suspected to contain a mine or other sought object, and the operating frequency would be swept over the band of

  18. Geochemical signatures of tsunami deposits - what do they tell us?

    NASA Astrophysics Data System (ADS)

    Chague-Goff, Catherine; Goff, James R.

    2010-05-01

    In the last two and half decades, but even more since the 2004 Indian Ocean Tsunami (IOT), there has been a significant increase in the amount of literature dealing with recent, historical and palaeotsunamis. Much has been written and debated about the diagnostic criteria of historical and palaeotsunami deposits. Most of the diagnostic criteria or proxies used reflect the expertise of the researchers involved and thus tend to be biased towards sedimentology, stratigraphy and micropalaeontology, with some reference to geomorphology, archaeology, anthropology and palynology. It should however be noted that all criteria have never been reported from one site, and neither are they all found in one single deposit. Thus, the lack of one or more proxies should not be taken as unique evidence to refute the tsunamigenic origin of a specific deposit. Although geochemical signatures have long been used as indicators for palaeosalinity in sedimentary sequences, there appears to have been some reluctance to use them to help in the identification of historical and palaeotsunami deposits. Like other proxies, geochemistry alone may not provide a definite answer to the origin of a deposit. Furthermore, poor preservation due to environmental conditions or as a result of post-diagenetic processes, might complicate the interpretation of geochemical signatures left by tsunami inundation. Similar taphonomic problems are also faced for microfossil proxies. However, geochemistry provides another piece to the puzzle, and together with other proxies, it can help identify palaeotsunami deposits. Geochemical signatures can also provide clues about the landward limit of runup of a tsunami, beyond the area of sediment deposition. This was recently documented following the 2004 IOT and the 2009 South Pacific tsunami. A summary of examples of geochemical signatures recorded in interstitial water and sediment of recent, historical and palaeotsunami deposits is presented.

  19. Microbial Signatures in Ooids from the Bahamas

    NASA Astrophysics Data System (ADS)

    Diaz, M. R.; Swart, P. K.; Devlin, Q.; Oehlert, A. M.; Saied, A.; Eberli, G. P.; Klaus, J. S.; Altabet, M.

    2013-12-01

    Microbes are abundant in sedimentary systems where their metabolic capabilities can exert a profound impact on carbonate precipitation processes by altering the alkalinity of their immediate surrounding. Using a combination of clone analysis of 16SrRNA, functional gene analysis and both inorganic and organic stable isotopic analyses, we characterized the microbial community structure of ooids and their potential functional capabilities that could lead to precipitation of carbonates. Oolitic bacterial communities were highly diverse, representing 12 different prokaryotic lineages, among which Alphaproteobacteria, Gammaproteobacteria, Actinobacteria/Bacteroidetes and Deltaproteobacteria were the most abundant. Based on functional gene analysis, a large number of genes were associated with redox dependent microbial communities with putative functional capability for mineral precipitation such as aerobic/anoxygenic photosynthesis, denitrification, ammonification, and sulfate reduction. In addition, a broad diversity of genes related to organic carbon degradation and nitrogen fixation were present, implying metabolic plasticity that enables survival under oligotrophic conditions. Carbon and nitrogen isotopic analyses, which were conducted on both bulk and intracrystalline organic matter as well as in leachate sediments, identified geochemical signatures of microbial activity. δ13C values for organic C in the bulk (-11.94 to -16.71) and intracrystalline organic matter (-12.37 to -17.66), were similar and within the range of fractionation patterns associated with cyanobacteria, algae and photosynthesizers that employ the C4 carbon fixation pathway. Nitrogen isotopic values for both bulk (δ15N: -0.314 to - 0.706) and intracrystalline organic matter (δ15N: -0.343 -1.70) also showed fractionation patterns consistent with nitrogen fixation. In addition, positive δ15N and δ18O values of the NO3- leached from the ooids provided evidence of denitrification. These findings

  20. Integrative Metabolic Signatures for Hepatic Radiation Injury

    PubMed Central

    Su, Gang; Meng, Fan; Liu, Laibin; Mohney, Robert; Kulkarni, Shilpa; Guha, Chandan

    2015-01-01

    Background Radiation-induced liver disease (RILD) is a dose-limiting factor in curative radiation therapy (RT) for liver cancers, making early detection of radiation-associated liver injury absolutely essential for medical intervention. A metabolomic approach was used to determine metabolic signatures that could serve as biomarkers for early detection of RILD in mice. Methods Anesthetized C57BL/6 mice received 0, 10 or 50 Gy Whole Liver Irradiation (WLI) and were contrasted to mice, which received 10 Gy whole body irradiation (WBI). Liver and plasma samples were collected at 24 hours after irradiation. The samples were processed using Gas Chromatography/Mass Spectrometry and Liquid Chromatography/Mass Spectrometry. Results Twenty four hours after WLI, 407 metabolites were detected in liver samples while 347 metabolites were detected in plasma. Plasma metabolites associated with 50 Gy WLI included several amino acids, purine and pyrimidine metabolites, microbial metabolites, and most prominently bradykinin and 3-indoxyl-sulfate. Liver metabolites associated with 50 Gy WLI included pentose phosphate, purine, and pyrimidine metabolites in liver. Plasma biomarkers in common between WLI and WBI were enriched in microbial metabolites such as 3 indoxyl sulfate, indole-3-lactic acid, phenyllactic acid, pipecolic acid, hippuric acid, and markers of DNA damage such as 2-deoxyuridine. Metabolites associated with tryptophan and indoles may reflect radiation-induced gut microbiome effects. Predominant liver biomarkers in common between WBI and WLI were amino acids, sugars, TCA metabolites (fumarate), fatty acids (lineolate, n-hexadecanoic acid) and DNA damage markers (uridine). Conclusions We identified a set of metabolomic markers that may prove useful as plasma biomarkers of RILD and WBI. Pathway analysis also suggested that the unique metabolic changes observed after liver irradiation was an integrative response of the intestine, liver and kidney. PMID:26046990

  1. Lipidome signatures in early bovine embryo development.

    PubMed

    Sudano, Mateus J; Rascado, Tatiana D S; Tata, Alessandra; Belaz, Katia R A; Santos, Vanessa G; Valente, Roniele S; Mesquita, Fernando S; Ferreira, Christina R; Araújo, João P; Eberlin, Marcos N; Landim-Alvarenga, Fernanda D C

    2016-07-15

    Mammalian preimplantation embryonic development is a complex, conserved, and well-orchestrated process involving dynamic molecular and structural changes. Understanding membrane lipid profile fluctuation during this crucial period is fundamental to address mechanisms governing embryogenesis. Therefore, the aim of the present work was to perform a comprehensive assessment of stage-specific lipid profiles during early bovine embryonic development and associate with the mRNA abundance of lipid metabolism-related genes (ACSL3, ELOVL5, and ELOVL6) and with the amount of cytoplasmic lipid droplets. Immature oocytes were recovered from slaughterhouse-derived ovaries, two-cell embryos, and eight- to 16-cell embryos, morula, and blastocysts that were in vitro produced under different environmental conditions. Lipid droplets content and mRNA transcript levels for ACSL3, ELOVL5, and ELOVL6, monitored by lipid staining and quantitative polymerase chain reaction, respectively, increased at morula followed by a decrease at blastocyst stage. Relative mRNA abundance changes of ACSL3 were closely related to cytoplasmic lipid droplet accumulation. Characteristic dynamic changes of phospholipid profiles were observed during early embryo development and related to unsaturation level, acyl chain length, and class composition. ELOVL5 and ELOVL6 mRNA levels were suggestive of overexpression of membrane phospholipids containing elongated fatty acids with 16, 18, and 20 carbons. In addition, putative biomarkers of key events of embryogenesis, embryo lipid accumulation, and elongation were identified. This study provides a comprehensive description of stage-specific lipidome signatures and proposes a mechanism to explain its potential relationship with the fluctuation of both cytoplasmic lipid droplets content and mRNA levels of lipid metabolism-related genes during early bovine embryo development. PMID:27107972

  2. Workshop on the Analysis of Interplanetary Dust Particles

    NASA Technical Reports Server (NTRS)

    Zolensky, Michael E. (Editor)

    1994-01-01

    Great progress has been made in the analysis of interplanetary dust particles (IDP's) over the past few years. This workshop provided a forum for the discussion of the following topics: observation and modeling of dust in the solar system, mineralogy and petrography of IDP's, processing of IDP's in the solar system and terrestrial atmosphere, comparison of IDP's to meteorites and micrometeorites, composition of IDP's, classification, and collection of IDP's.

  3. Quantum mechanical stabilization of Minkowski signature wormholes

    SciTech Connect

    Visser, M.

    1989-05-19

    When one attempts to construct classical wormholes in Minkowski signature Lorentzian spacetimes violations of both the weak energy hypothesis and averaged weak energy hypothesis are encountered. Since the weak energy hypothesis is experimentally known to be violated quantum mechanically, this suggests that a quantum mechanical analysis of Minkowski signature wormholes is in order. In this note I perform a minisuperspace analysis of a simple class of Minkowski signature wormholes. By solving the Wheeler-de Witt equation for pure Einstein gravity on this minisuperspace the quantum mechanical wave function of the wormhole is obtained in closed form. The wormhole is shown to be quantum mechanically stabilized with an average radius of order the Planck length. 8 refs.

  4. Estimating physiological skin parameters from hyperspectral signatures.

    PubMed

    Vyas, Saurabh; Banerjee, Amit; Burlina, Philippe

    2013-05-01

    We describe an approach for estimating human skin parameters, such as melanosome concentration, collagen concentration, oxygen saturation, and blood volume, using hyperspectral radiometric measurements (signatures) obtained from in vivo skin. We use a computational model based on Kubelka-Munk theory and the Fresnel equations. This model forward maps the skin parameters to a corresponding multiband reflectance spectra. Machine-learning-based regression is used to generate the inverse map, and hence estimate skin parameters from hyperspectral signatures. We test our methods using synthetic and in vivo skin signatures obtained in the visible through the short wave infrared domains from 24 patients of both genders and Caucasian, Asian, and African American ethnicities. Performance validation shows promising results: good agreement with the ground truth and well-established physiological precepts. These methods have potential use in the characterization of skin abnormalities and in minimally-invasive prescreening of malignant skin cancers. PMID:23722495

  5. Selection Signatures in Worldwide Sheep Populations

    PubMed Central

    Fariello, Maria-Ines; Servin, Bertrand; Tosser-Klopp, Gwenola; Rupp, Rachel; Moreno, Carole; Cristobal, Magali San; Boitard, Simon

    2014-01-01

    The diversity of populations in domestic species offers great opportunities to study genome response to selection. The recently published Sheep HapMap dataset is a great example of characterization of the world wide genetic diversity in sheep. In this study, we re-analyzed the Sheep HapMap dataset to identify selection signatures in worldwide sheep populations. Compared to previous analyses, we made use of statistical methods that (i) take account of the hierarchical structure of sheep populations, (ii) make use of linkage disequilibrium information and (iii) focus specifically on either recent or older selection signatures. We show that this allows pinpointing several new selection signatures in the sheep genome and distinguishing those related to modern breeding objectives and to earlier post-domestication constraints. The newly identified regions, together with the ones previously identified, reveal the extensive genome response to selection on morphology, color and adaptation to new environments. PMID:25126940

  6. A Methodology for Calculating Radiation Signatures

    SciTech Connect

    Klasky, Marc Louis; Wilcox, Trevor; Bathke, Charles G.; James, Michael R.

    2015-05-01

    A rigorous formalism is presented for calculating radiation signatures from both Special Nuclear Material (SNM) as well as radiological sources. The use of MCNP6 in conjunction with CINDER/ORIGEN is described to allow for the determination of both neutron and photon leakages from objects of interest. In addition, a description of the use of MCNP6 to properly model the background neutron and photon sources is also presented. Examinations of the physics issues encountered in the modeling are investigated so as to allow for guidance in the user discerning the relevant physics to incorporate into general radiation signature calculations. Furthermore, examples are provided to assist in delineating the pertinent physics that must be accounted for. Finally, examples of detector modeling utilizing MCNP are provided along with a discussion on the generation of Receiver Operating Curves, which are the suggested means by which to determine detectability radiation signatures emanating from objects.

  7. Temporal shape analysis via the spectral signature.

    PubMed

    Bernardis, Elena; Konukoglu, Ender; Ou, Yangming; Metaxas, Dimitris N; Desjardins, Benoit; Pohl, Kilian M

    2012-01-01

    In this paper, we adapt spectral signatures for capturing morphological changes over time. Advanced techniques for capturing temporal shape changes frequently rely on first registering the sequence of shapes and then analyzing the corresponding set of high dimensional deformation maps. Instead, we propose a simple encoding motivated by the observation that small shape deformations lead to minor refinements in the spectral signature composed of the eigenvalues of the Laplace operator. The proposed encoding does not require registration, since spectral signatures are invariant to pose changes. We apply our representation to the shapes of the ventricles extracted from 22 cine MR scans of healthy controls and Tetralogy of Fallot patients. We then measure the accuracy score of our encoding by training a linear classifier, which outperforms the same classifier based on volumetric measurements. PMID:23286031

  8. Animal Models of Interferon Signature Positive Lupus.

    PubMed

    Zhuang, Haoyang; Szeto, Christopher; Han, Shuhong; Yang, Lijun; Reeves, Westley H

    2015-01-01

    Human lupus is strongly associated with a gene expression signature characterized by over-expression of Type I interferon-regulated genes. A strong interferon signature generally is not seen in the standard mouse models of lupus, despite considerable evidence for the involvement of toll-like receptor-driven interferon production. In contrast, pristane-induced lupus exhibits a prominent TLR7-dependent interferon signature. Importantly, genetic disorders with dysregulated interferon production in both human beings and mice cause severe autoinflammatory diseases but not the typical manifestations of lupus, suggesting that interferon over-production is insufficient to cause systemic lupus erythematosus itself. Single-gene models in mice suggest that lupus-like disease may result from abnormalities in B-cell activation and the clearance of dead cells. Pristane may mimic human systemic lupus erythematosus by causing synergistic abnormalities in interferon production along with defective clearance of apoptotic cells and over-active B-cell signaling. PMID:26097482

  9. Animal Models of Interferon Signature Positive Lupus

    PubMed Central

    Zhuang, Haoyang; Szeto, Christopher; Han, Shuhong; Yang, Lijun; Reeves, Westley H.

    2015-01-01

    Human lupus is strongly associated with a gene expression signature characterized by over-expression of Type I interferon-regulated genes. A strong interferon signature generally is not seen in the standard mouse models of lupus, despite considerable evidence for the involvement of toll-like receptor-driven interferon production. In contrast, pristane-induced lupus exhibits a prominent TLR7-dependent interferon signature. Importantly, genetic disorders with dysregulated interferon production in both human beings and mice cause severe autoinflammatory diseases but not the typical manifestations of lupus, suggesting that interferon over-production is insufficient to cause systemic lupus erythematosus itself. Single-gene models in mice suggest that lupus-like disease may result from abnormalities in B-cell activation and the clearance of dead cells. Pristane may mimic human systemic lupus erythematosus by causing synergistic abnormalities in interferon production along with defective clearance of apoptotic cells and over-active B-cell signaling. PMID:26097482

  10. Mutations in the K+ channel signature sequence.

    PubMed Central

    Heginbotham, L; Lu, Z; Abramson, T; MacKinnon, R

    1994-01-01

    Potassium channels share a highly conserved stretch of eight amino acids, a K+ channel signature sequence. The conserved sequence falls within the previously defined P-region of voltage-activated K+ channels. In this study we investigate the effect of mutations in the signature sequence of the Shaker channel on K+ selectivity determined under bi-ionic conditions. Nonconservative substitutions of two threonine residues and the tyrosine residue leave selectivity intact. In contrast, mutations at some positions render the channel nonselective among monovalent cations. These findings are consistent with a proposal that the signature sequence contributes to a selectivity filter. Furthermore, the results illustrate that the hydroxyl groups at the third and fourth positions, and the aromatic group at position seven, are not essential in determining K+ selectivity. Images FIGURE 1 PMID:8038378

  11. Biomarker Gene Signature Discovery Integrating Network Knowledge

    PubMed Central

    Cun, Yupeng; Fröhlich, Holger

    2012-01-01

    Discovery of prognostic and diagnostic biomarker gene signatures for diseases, such as cancer, is seen as a major step towards a better personalized medicine. During the last decade various methods, mainly coming from the machine learning or statistical domain, have been proposed for that purpose. However, one important obstacle for making gene signatures a standard tool in clinical diagnosis is the typical low reproducibility of these signatures combined with the difficulty to achieve a clear biological interpretation. For that purpose in the last years there has been a growing interest in approaches that try to integrate information from molecular interaction networks. Here we review the current state of research in this field by giving an overview about so-far proposed approaches. PMID:24832044

  12. Cryptanalysis of the arbitrated quantum signature protocols

    SciTech Connect

    Gao Fei; Qin Sujuan; Guo Fenzhuo; Wen Qiaoyan

    2011-08-15

    As a new model for signing quantum messages, arbitrated quantum signature (AQS) has recently received a lot of attention. In this paper we study the cryptanalysis of previous AQS protocols from the aspects of forgery and disavowal. We show that in these protocols the receiver, Bob, can realize existential forgery of the sender's signature under known message attack. Bob can even achieve universal forgery when the protocols are used to sign a classical message. Furthermore, the sender, Alice, can successfully disavow any of her signatures by simple attack. The attack strategies are described in detail and some discussions about the potential improvements of the protocols are given. Finally we also present several interesting topics on AQS protocols that can be studied in future.

  13. Explosives Detection: Exploitation of the Physical Signatures

    NASA Astrophysics Data System (ADS)

    Atkinson, David

    2010-10-01

    Explosives based terrorism is an ongoing threat that is evolving with respect to implementation, configuration and materials used. There are a variety of devices designed to detect explosive devices, however, each technology has limitations and operational constraints. A full understanding of the signatures available for detection coupled with the array of detection choices can be used to develop a conceptual model of an explosives screening operation. Physics based sensors provide a robust approach to explosives detection, typically through the identification of anomalies, and are currently used for screening in airports around the world. The next generation of detectors for explosives detection will need to be more sensitive and selective, as well as integrate seamlessly with devices focused on chemical signatures. An appreciation for the details of the physical signature exploitation in cluttered environments with time, space, and privacy constraints is necessary for effective explosives screening of people, luggage, cargo, and vehicles.

  14. Estimating physiological skin parameters from hyperspectral signatures

    NASA Astrophysics Data System (ADS)

    Vyas, Saurabh; Banerjee, Amit; Burlina, Philippe

    2013-05-01

    We describe an approach for estimating human skin parameters, such as melanosome concentration, collagen concentration, oxygen saturation, and blood volume, using hyperspectral radiometric measurements (signatures) obtained from in vivo skin. We use a computational model based on Kubelka-Munk theory and the Fresnel equations. This model forward maps the skin parameters to a corresponding multiband reflectance spectra. Machine-learning-based regression is used to generate the inverse map, and hence estimate skin parameters from hyperspectral signatures. We test our methods using synthetic and in vivo skin signatures obtained in the visible through the short wave infrared domains from 24 patients of both genders and Caucasian, Asian, and African American ethnicities. Performance validation shows promising results: good agreement with the ground truth and well-established physiological precepts. These methods have potential use in the characterization of skin abnormalities and in minimally-invasive prescreening of malignant skin cancers.

  15. Nitrogen isotopic signatures in the Acapulco meteorite

    NASA Technical Reports Server (NTRS)

    Sturgeon, G.; Marti, K.

    1991-01-01

    N isotopic abundances are reported for a bulk sample of the unique meteorite Acapulco. Although the mineral chemistry indicates a high degree of recrystallization under redox conditions between those of H and E chondrites (Palme et al., 1981), the presence of two distinct N isotopic signatures shows that the carriers of these N components were not equilibrated. In stepwise pyrolysis, the larger (65 percent) N component is released mostly below 1000 C and reveals a signature of delta(N-15) = 8.9 + or - 1.2 per mil, which is within the range observed in chondrites. A second 'light' component appears above 1000 C and has a signature of delta(N-15) less than or equal to -110.5 + or - 4.0 per mil (uncorrected for spallation N-15).

  16. Cryptanalysis of the arbitrated quantum signature protocols

    NASA Astrophysics Data System (ADS)

    Gao, Fei; Qin, Su-Juan; Guo, Fen-Zhuo; Wen, Qiao-Yan

    2011-08-01

    As a new model for signing quantum messages, arbitrated quantum signature (AQS) has recently received a lot of attention. In this paper we study the cryptanalysis of previous AQS protocols from the aspects of forgery and disavowal. We show that in these protocols the receiver, Bob, can realize existential forgery of the sender's signature under known message attack. Bob can even achieve universal forgery when the protocols are used to sign a classical message. Furthermore, the sender, Alice, can successfully disavow any of her signatures by simple attack. The attack strategies are described in detail and some discussions about the potential improvements of the protocols are given. Finally we also present several interesting topics on AQS protocols that can be studied in future.

  17. Neutral and adaptive genomic signatures of rapid poleward range expansion.

    PubMed

    Swaegers, J; Mergeay, J; Van Geystelen, A; Therry, L; Larmuseau, M H D; Stoks, R

    2015-12-01

    Many species are expanding their range polewards, and this has been associated with rapid phenotypic change. Yet, it is unclear to what extent this reflects rapid genetic adaptation or neutral processes associated with range expansion, or selection linked to the new thermal conditions encountered. To disentangle these alternatives, we studied the genomic signature of range expansion in the damselfly Coenagrion scitulum using 4950 newly developed genomic SNPs and linked this to the rapidly evolved phenotypic differences between core and (newly established) edge populations. Most edge populations were genetically clearly differentiated from the core populations and all were differentiated from each other indicating independent range expansion events. In addition, evidence for genetic drift in the edge populations, and strong evidence for adaptive genetic variation in association with the range expansion was detected. We identified one SNP under consistent selection in four of the five edge populations and showed that the allele increasing in frequency is associated with increased flight performance. This indicates collateral, non-neutral evolutionary changes in independent edge populations driven by the range expansion process. We also detected a genomic signature of adaptation to the newly encountered thermal regimes, reflecting a pattern of countergradient variation. The latter signature was identified at a single SNP as well as in a set of covarying SNPs using a polygenic multilocus approach to detect selection. Overall, this study highlights how a strategic geographic sampling design and the integration of genomic, phenotypic and environmental data can identify and disentangle the neutral and adaptive processes that are simultaneously operating during range expansions. PMID:26561985

  18. Development of Asset Fault Signatures for Prognostic and Health Management in the Nuclear Industry

    SciTech Connect

    Vivek Agarwal; Nancy J. Lybeck; Randall Bickford; Richard Rusaw

    2014-06-01

    Proactive online monitoring in the nuclear industry is being explored using the Electric Power Research Institute’s Fleet-Wide Prognostic and Health Management (FW-PHM) Suite software. The FW-PHM Suite is a set of web-based diagnostic and prognostic tools and databases that serves as an integrated health monitoring architecture. The FW-PHM Suite has four main modules: Diagnostic Advisor, Asset Fault Signature (AFS) Database, Remaining Useful Life Advisor, and Remaining Useful Life Database. This paper focuses on development of asset fault signatures to assess the health status of generator step-up generators and emergency diesel generators in nuclear power plants. Asset fault signatures describe the distinctive features based on technical examinations that can be used to detect a specific fault type. At the most basic level, fault signatures are comprised of an asset type, a fault type, and a set of one or more fault features (symptoms) that are indicative of the specified fault. The AFS Database is populated with asset fault signatures via a content development exercise that is based on the results of intensive technical research and on the knowledge and experience of technical experts. The developed fault signatures capture this knowledge and implement it in a standardized approach, thereby streamlining the diagnostic and prognostic process. This will support the automation of proactive online monitoring techniques in nuclear power plants to diagnose incipient faults, perform proactive maintenance, and estimate the remaining useful life of assets.

  19. A genome signature derived from the interplay of word frequencies and symbol correlations

    NASA Astrophysics Data System (ADS)

    Möller, Simon; Hameister, Heike; Hütt, Marc-Thorsten

    2014-11-01

    Genome signatures are statistical properties of DNA sequences that provide information on the underlying species. It is not understood, how such species-discriminating statistical properties arise from processes of genome evolution and from functional properties of the DNA. Investigating the interplay of different genome signatures can contribute to this understanding. Here we analyze the statistical dependences of two such genome signatures: word frequencies and symbol correlations at short and intermediate distances. We formulate a statistical model of word frequencies in DNA sequences based on the observed symbol correlations and show that deviations of word counts from this correlation-based null model serve as a new genome signature. This signature (i) performs better in sorting DNA sequence segments according to their species origin and (ii) reveals unexpected species differences in the composition of microsatellites, an important class of repetitive DNA. While the first observation is a typical task in metagenomics projects and therefore an important benchmark for a genome signature, the latter suggests strong species differences in the biological mechanisms of genome evolution. On a more general level, our results highlight that the choice of null model (here: word abundances computed via symbol correlations rather than shorter word counts) substantially affects the interpretation of such statistical signals.

  20. Spectral Signatures in the Classroom

    ERIC Educational Resources Information Center

    Huber, Thomas P.

    2004-01-01

    Ensuring that students understand the basis behind their geography/science courses is an essential part of their education. This article looks at an inexpensive and rigorous way of teaching students how to develop the needed data for remote sensing work. The procedure shows instructors how to build a system to teach students the process of…

  1. KEA-71 Smart Current Signature Sensor (SCSS)

    NASA Technical Reports Server (NTRS)

    Perotti, Jose M.

    2010-01-01

    This slide presentation reviews the development and uses of the Smart Current Signature Sensor (SCSS), also known as the Valve Health Monitor (VHM) system. SCSS provides a way to not only monitor real-time the valve's operation in a non invasive manner, but also to monitor its health (Fault Detection and Isolation) and identify potential faults and/or degradation in the near future (Prediction/Prognosis). This technology approach is not only applicable for solenoid valves, and it could be extrapolated to other electrical components with repeatable electrical current signatures such as motors.

  2. Characterization of marine macroalgae by fluorescence signatures

    NASA Technical Reports Server (NTRS)

    Topinka, J. A.; Bellows, W. Korjeff; Yentsch, C. S.

    1990-01-01

    The feasibility of distinguishing macroalgal classes by their fluorescence signatures was investigated using narrow-waveband light to excite groups of accessory pigments in brown, red, and green macroalgae and measuring fluorescence emission at 685 nm. Results obtained on 20 marine macroalgae field-collected samples showed that fluorescence excitation signatures were relatively uniform within phylogenetic classes but were substantially different for different classes. It is suggested that it may be possible to characterize the type and the abundance of subtidal macroalgae from low-flying aircraft using existing laser-induced fluorescence methodology.

  3. Transient aspects of stream interface signatures

    SciTech Connect

    Crooker, N.U.; Shodhan, S.; Forsyth, R.J.; Burton, M.E.; Gosling, J.T.; Fitzenreiter, R.J.; Lepping, R.P.

    1999-06-01

    Although stream interfaces are steady-state, corotating boundaries between slow and fast solar wind, their signatures are sometimes associated with transient features. Here the authors illustrate two modes of association: interfaces trailing interplanetary coronal mass ejections (ICMEs) at 1 AU and interfaces within ICMEs in the range 4--5 AU. The former are readily understood as boundaries between transient slow wind and steady-state fast wind, where the ICMEs add variability to the interface signatures. The latter are puzzling and may be related to evolution of interfaces.

  4. Stochastic monotony signature and biomedical applications.

    PubMed

    Demongeot, Jacques; Galli Carminati, Giuliana; Carminati, Federico; Rachdi, Mustapha

    2015-12-01

    We introduce a new concept, the stochastic monotony signature of a function, made of the sequence of the signs that indicate if the function is increasing or constant (sign +), or decreasing (sign -). If the function results from the averaging of successive observations with errors, the monotony sign is a random binary variable, whose density is studied under two hypotheses for the distribution of errors: uniform and Gaussian. Then, we describe a simple statistical test allowing the comparison between the monotony signatures of two functions (e.g., one observed and the other as reference) and we apply the test to four biomedical examples, coming from genetics, psychology, gerontology, and morphogenesis. PMID:26563556

  5. Plasma Signatures of Radial Field Power Dropouts

    SciTech Connect

    Lucek, E.A.; Horbury, T.S.; Balogh, A.; McComas, D.J.

    1998-10-04

    A class of small scale structures, with a near-radial magnetic field and a drop in magnetic field fluctuation power, have recently been identified in the polar solar wind. An earlier study of 24 events, each lasting for 6 hours or more, identified no clear plasma signature. In an extension of that work, radial intervals lasting for 4 hours or more (89 in total), have been used to search for a statistically significant plasma signature. It was found that, despite considerable variations between intervals, there was a small but significant drop, on average, in plasma temperature, density and {beta} during these events.

  6. Radar polarization signatures of vegetated areas

    NASA Technical Reports Server (NTRS)

    Van Zyl, Jakob J.; Zebker, Howard A.

    1987-01-01

    A simple model is presented for the prediction of the full polarization signature of vegetation resembling tall grass. This polarization signature can be used to detect the presence of vegetation even in those cases in which the vegetation layers are comparatively thin. Also presented is a model which predicts the polarization dependence of different tree types. Attention is given to the cases of pine and deciduous forest model predictions; both types of forest can be expected to contain terms representing the scatter from the ground, as well as forward, double reflections from the ground and limbs/trunk.

  7. Lyman edges - Signatures of accretion disks

    NASA Astrophysics Data System (ADS)

    Kinney, A. L.

    1992-05-01

    Accretion disks are thought to provide the ultraviolet emission seen in the big blue bump of quasars. However, observations of the UV spectra of quasars do not show the additional signatures predicted by the accretion disk models. This paper will concentrate on just one of those signatures - the Lyman edge. Two studies are briefly discussed which explore the Lyman edge region of both high and low redshift quasars (Antonucci, Kinney, and Ford 1989 and Koratkar, Kinney, and Bohlin 1992). Both studies find that Lyman edges are not present in quasar spectra as frequently as predicted by the models or at the strength predicted by accretion disk models.

  8. Security problem on arbitrated quantum signature schemes

    SciTech Connect

    Choi, Jeong Woon; Chang, Ku-Young; Hong, Dowon

    2011-12-15

    Many arbitrated quantum signature schemes implemented with the help of a trusted third party have been developed up to now. In order to guarantee unconditional security, most of them take advantage of the optimal quantum one-time encryption based on Pauli operators. However, in this paper we point out that the previous schemes provide security only against a total break attack and show in fact that there exists an existential forgery attack that can validly modify the transmitted pair of message and signature. In addition, we also provide a simple method to recover security against the proposed attack.

  9. Security problem on arbitrated quantum signature schemes

    NASA Astrophysics Data System (ADS)

    Choi, Jeong Woon; Chang, Ku-Young; Hong, Dowon

    2011-12-01

    Many arbitrated quantum signature schemes implemented with the help of a trusted third party have been developed up to now. In order to guarantee unconditional security, most of them take advantage of the optimal quantum one-time encryption based on Pauli operators. However, in this paper we point out that the previous schemes provide security only against a total break attack and show in fact that there exists an existential forgery attack that can validly modify the transmitted pair of message and signature. In addition, we also provide a simple method to recover security against the proposed attack.

  10. Cryptanalysis of the Quantum Group Signature Protocols

    NASA Astrophysics Data System (ADS)

    Zhang, Ke-Jia; Sun, Ying; Song, Ting-Ting; Zuo, Hui-Juan

    2013-11-01

    Recently, the researches of quantum group signature (QGS) have attracted a lot of attentions and some typical protocols have been designed for e-payment system, e-government, e-business, etc. In this paper, we analyze the security of the quantum group signature with the example of two novel protocols. It can be seen that both of them cannot be implemented securely since the arbitrator cannot solve the disputes fairly. In order to show that, some possible attack strategies, which can be used by the malicious participants, are proposed. Moreover, the further discussions of QGS are presented finally, including some insecurity factors and improved ideas.

  11. A Electronic Voting Scheme Achieved by Using Quantum Proxy Signature

    NASA Astrophysics Data System (ADS)

    Cao, Hai-Jing; Ding, Li-Yuan; Yu, Yao-Feng; Li, Peng-Fei

    2016-09-01

    In this paper, we propose a new electronic voting scheme using Bell entangled states as quantum channels. This scheme is based on quantum proxy signature. The voter Alice, vote management center Bob, teller Charlie and scrutineer Diana only perform single particle measurement to realize the electronic voting process. So the scheme reduces the technical difficulty and increases operation efficiency. It can be easily realized. We use quantum key distribution and one-time pad to guarantee its unconditional security. The scheme uses the physical characteristics of quantum mechanics to guarantee its anonymity, verifiability, unforgetability and undeniability.

  12. A Electronic Voting Scheme Achieved by Using Quantum Proxy Signature

    NASA Astrophysics Data System (ADS)

    Cao, Hai-Jing; Ding, Li-Yuan; Yu, Yao-Feng; Li, Peng-Fei

    2016-06-01

    In this paper, we propose a new electronic voting scheme using Bell entangled states as quantum channels. This scheme is based on quantum proxy signature. The voter Alice, vote management center Bob, teller Charlie and scrutineer Diana only perform single particle measurement to realize the electronic voting process. So the scheme reduces the technical difficulty and increases operation efficiency. It can be easily realized. We use quantum key distribution and one-time pad to guarantee its unconditional security. The scheme uses the physical characteristics of quantum mechanics to guarantee its anonymity, verifiability, unforgetability and undeniability.

  13. Quantum Signature of Analog Hawking Radiation in Momentum Space.

    PubMed

    Boiron, D; Fabbri, A; Larré, P-É; Pavloff, N; Westbrook, C I; Ziń, P

    2015-07-10

    We consider a sonic analog of a black hole realized in the one-dimensional flow of a Bose-Einstein condensate. Our theoretical analysis demonstrates that one- and two-body momentum distributions accessible by present-day experimental techniques provide clear direct evidence (i) of the occurrence of a sonic horizon, (ii) of the associated acoustic Hawking radiation, and (iii) of the quantum nature of the Hawking process. The signature of the quantum behavior persists even at temperatures larger than the chemical potential. PMID:26207475

  14. Attack and improvements of fair quantum blind signature schemes

    NASA Astrophysics Data System (ADS)

    Zou, Xiangfu; Qiu, Daowen

    2013-06-01

    Blind signature schemes allow users to obtain the signature of a message while the signer learns neither the message nor the resulting signature. Therefore, blind signatures have been used to realize cryptographic protocols providing the anonymity of some participants, such as: secure electronic payment systems and electronic voting systems. A fair blind signature is a form of blind signature which the anonymity could be removed with the help of a trusted entity, when this is required for legal reasons. Recently, a fair quantum blind signature scheme was proposed and thought to be safe. In this paper, we first point out that there exists a new attack on fair quantum blind signature schemes. The attack shows that, if any sender has intercepted any valid signature, he (she) can counterfeit a valid signature for any message and can not be traced by the counterfeited blind signature. Then, we construct a fair quantum blind signature scheme by improved the existed one. The proposed fair quantum blind signature scheme can resist the preceding attack. Furthermore, we demonstrate the security of the proposed fair quantum blind signature scheme and compare it with the other one.

  15. Sputum RNA signature in allergic asthmatics following allergen bronchoprovocation test

    PubMed Central

    Zuiker, Rob G.J.A.; Tribouley, Catherine; Diamant, Zuzana; Boot, J. Diderik; Cohen, Adam F.; Van Dyck, K.; De Lepeleire, I.; Rivas, Veronica M.; Malkov, Vladislav A.; Burggraaf, Jacobus; Ruddy, Marcella K.

    2016-01-01

    Background Inhaled allergen challenge is a validated disease model of allergic asthma offering useful pharmacodynamic assessment of pharmacotherapeutic effects in a limited number of subjects. Objectives To evaluate whether an RNA signature can be identified from induced sputum following an inhaled allergen challenge, whether a RNA signature could be modulated by limited doses of inhaled fluticasone, and whether these gene expression profiles would correlate with the clinical endpoints measured in this study. Methods Thirteen non-smoking, allergic subjects with mild-to-moderate asthma participated in a randomised, placebo-controlled, 2-period cross-over study following a single-blind placebo run-in period. Each period consisted of three consecutive days, separated by a wash-out period of at least 3 weeks. Subjects randomly received inhaled fluticasone ((FP) MDI; 500 mcg BID×5 doses in total) or placebo. On day 2, house dust mite extract was inhaled and airway response was measured by FEV1 at predefined time points until 7 h post-allergen. Sputum was induced by NaCl 4.5%, processed and analysed at 24 h pre-allergen and 7 and 24 h post-allergen. RNA was isolated from eligible sputum cell pellets (<80% squamous of 500 cells), amplified according to NuGEN technology, and profiled on Affymetrix arrays. Gene expression changes from baseline and fluticasone treatment effects were evaluated using a mixed effects ANCOVA model at 7 and at 24 h post-allergen challenge. Results Inhaled allergen-induced statistically significant gene expression changes in sputum, which were effectively blunted by fluticasone (adjusted p<0.025). Forty-seven RNA signatures were selected from these responses for correlation analyses and further validation. This included Th2 mRNA levels for cytokines, chemokines, high-affinity IgE receptor FCER1A, histamine receptor HRH4, and enzymes and receptors in the arachidonic pathway. Individual messengers from the 47 RNA signatures correlated significantly

  16. Continental collisions and seismic signature

    NASA Astrophysics Data System (ADS)

    Meissner, R.; Wever, Th.; Sadowiak, P.

    1991-04-01

    Reflection seismics in compressional belts has revealed the structure of crustal shortening and thickening processes, showing complex patterns of indentation and interfingering of colliding crusts and subcrustal lithospheres. Generally, in the upper crust large zones of detachments develop, often showing duplexes and 'crocodile' structures. The lower crust from zones of active collision (e.g. Alps, Pyrenees) is characterized by strongly dipping reflections. The base of the crust with the Moho must be continuously equilibrating after orogenic collapse as areas of former continental collision exhibit flat Mohos and subhorizontal reflections. The depth to the Moho increases during collision and decreases after the onset of post-orogenic extension, until finally the crustal root disappears completely together with the erosion of the mountains. Processes, active during continental collisions and orogenic collapse, create distinct structures which are imaged by reflection seismic profiling. Examples are shown and discussed.

  17. Extraction and analysis of the width, gray scale and radian in Chinese signature handwriting.

    PubMed

    Chen, Xiaohong

    2015-10-01

    Forensic handwriting examination is a relevant identification process in forensic science. This research obtained ideas from the process of features detection and analysis in forensic handwriting examination. A Chinese signature database was developed and comprised original signatures, freehand imitation forgeries, random forgeries and tracing imitation forgeries. The features of width, gray scale and radian combined with stroke orders were automatically extracted after image processing. A correlation coefficient was used to precisely characterize and express the similarities between signatures. To validate the differences between writers, a multivariate analysis of the variance was employed. The canonical discriminant analysis was performed between the original and non-original signatures; the cross-validation estimated the discriminating power of the width, gray scale and radian data. It is suggested that the extraction and analysis of these properties in Chinese signatures is reasonable. Meanwhile, forensic handwriting examination using the quantitative feature extraction and statistical analysis methods in this research could be performed with a satisfactory result in the discriminant analysis. PMID:26209129

  18. Offline signature verification using local binary pattern and octave pattern

    NASA Astrophysics Data System (ADS)

    Ahlawat, Sahil; Goel, Anubhav; Prasad, Surabhi; Singh, Preety

    2014-01-01

    Signature verification holds a significant place in today's world as most of the bank transactions, stock trading etc. are validated via signatures. Signatures are considered as one of the most effective biometric identity but unfortunately signature forgery attempts are quite rampant. To prevent this, a robust signature verification mechanism is essential. In this paper, a new method has been proposed which uses Local Binary Pattern and geometrical features. A new geometric property has been devised i.e. Octave Pattern. Performance is analyzed by comparing random, semi-skilled and skilled forgeries with the genuine signature.

  19. A group signature scheme based on quantum teleportation

    NASA Astrophysics Data System (ADS)

    Wen, Xiaojun; Tian, Yuan; Ji, Liping; Niu, Xiamu

    2010-05-01

    In this paper, we present a group signature scheme using quantum teleportation. Different from classical group signature and current quantum signature schemes, which could only deliver either group signature or unconditional security, our scheme guarantees both by adopting quantum key preparation, quantum encryption algorithm and quantum teleportation. Security analysis proved that our scheme has the characteristics of group signature, non-counterfeit, non-disavowal, blindness and traceability. Our quantum group signature scheme has a foreseeable application in the e-payment system, e-government, e-business, etc.

  20. Joint Estimation of Time-Frequency Signature and DOA Based on STFD for Multicomponent Chirp Signals.

    PubMed

    Zhao, Ziyue; Liu, Congfeng

    2014-01-01

    In the study of the joint estimation of time-frequency signature and direction of arrival (DOA) for multicomponent chirp signals, an estimation method based on spatial time-frequency distributions (STFDs) is proposed in this paper. Firstly, array signal model for multicomponent chirp signals is presented and then array processing is applied in time-frequency analysis to mitigate cross-terms. According to the results of the array processing, Hough transform is performed and the estimation of time-frequency signature is obtained. Subsequently, subspace method for DOA estimation based on STFD matrix is achieved. Simulation results demonstrate the validity of the proposed method. PMID:27382610

  1. Joint Estimation of Time-Frequency Signature and DOA Based on STFD for Multicomponent Chirp Signals

    PubMed Central

    Zhao, Ziyue; Liu, Congfeng

    2014-01-01

    In the study of the joint estimation of time-frequency signature and direction of arrival (DOA) for multicomponent chirp signals, an estimation method based on spatial time-frequency distributions (STFDs) is proposed in this paper. Firstly, array signal model for multicomponent chirp signals is presented and then array processing is applied in time-frequency analysis to mitigate cross-terms. According to the results of the array processing, Hough transform is performed and the estimation of time-frequency signature is obtained. Subsequently, subspace method for DOA estimation based on STFD matrix is achieved. Simulation results demonstrate the validity of the proposed method. PMID:27382610

  2. Ground signatures of dayside magnetospheric boundary-layer phenomena

    SciTech Connect

    McHenry, M.A.

    1989-01-01

    Solar wind momentum at the Earth's magnetopause causes plasma to circulate inside the magnetosphere and in the ionosphere. Satellite observations have shown that two momentum exchange processes, magnetic reconnection and viscous interaction, are active. Associated with these, localized, sporadic changes in the electric currents and plasma velocity occur in the high latitude ionosphere; i.e. deep inside the terrestrial magnetosphere. In this study continuous, multiple point, ground based observations of the ionosphere are used to study features of the magnetopause related to reconnection and viscous interaction. Flux transfer events (FTEs) are one type of magnetic reconnection process observed at the magnetopause. Two FTE field-aligned current systems, which presumedly interact with the ionosphere, have been inferred and postulated. In this study an analysis is made of the expected ground magnetic field of these small-scale, field-aligned current systems interacting with the ionosphere. The effects of ground induction which occur when the current systems move relative to a ground observer is also examined. The author believes the lack of FTE signatures in ground observations may be due to the small area of the FTE ground signature or to a more complex FTE field aligned current system. Observations of ground magnetic field perturbations using a Greenland magnetometer chain show that traveling perturbations similar to the predicted FTE signatures exist in the high latitude ionosphere. The perturbations have a field-aligned current concentrated into filaments producing a radical ground magnetic field and an azimuthal, or vortex-like flow, plasma flow in the ionosphere.

  3. Pickup Ion Signatures in the Vicinity of Titan

    NASA Astrophysics Data System (ADS)

    Regoli, L.; Coates, A. J.; Feyerabend, M.; Roussos, E.; Jones, G. H.; Krupp, N.; Thomsen, M. F.

    2015-12-01

    Being the only moon in the solar system with a significant atmosphere, Titan possesses an ionosphere that acts as a conducting obstacle to the incoming plasma from Saturn's magnetosphere. This creates a mass-loading of the magnetic field lines with freshly picked up ions from Titan's atmosphere on a process similar to that observed in comets (e.g. Coates et al. (1993), Journal of Geophysical Research, Vol. 98, No. A12, 20985-20994) and other moons like Jupiter's Io (e.g. Russell et al. (2003), Planetary and Space Science, Vol. 51, 233-238). However, while at other celestial bodies ion cyclotron waves arise as one of the main signatures of this process, this is not the case at Titan, with e.g. Cowee et al. (2010) (Journal of Geophysical Research, Vol. 115, A10224) attributing this to the local orientation of the magnetic field and the plasma flow preventing the waves to grow to levels detectable by the instruments on-board Cassini. For the reason above, the detection of pickup ions signatures needs to be approached through other methods. For this study, we analyze data from the CAPS/IMS instrument on-board Cassini. IMS is an ion mass spectrometer capable of detecting ion fluxes with energies from 1 eV to 50 keV with an atomic resolution of M/ΔM ~ 70. During many of the dedicated Titan flybys by Cassini, IMS was able to distinguish between ions of magnetospheric origin and of ionospheric origin, the latter being freshly picked up ions from Titan's ionosphere. With the help of ion spectrograms and time of flight (TOF) information, we carried out a survey of all the flybys for which IMS has data (the CAPS instrument was switched off after the 83th. dedicated flyby, named in the project as T83) in order to obtain information about the location and frequency of occurence for the signatures.

  4. Vulcanian explosions: precursory and eruptive signatures from a multiparameteric perspective

    NASA Astrophysics Data System (ADS)

    Gottsmann, J.; De Angelis, S.; Fournier, N.; Sacks, S. I.; Van Camp, M. J.; Linde, A. T.; Ripepe, M.

    2012-12-01

    Vulcanian explosions: precursory and eruptive signatures from a multiparameteric perspective Vulcanian eruptions form a continuum ranging from the weaker Strombolian-type to violent sub-Plinian activity. They are short-lived (tens of seconds to tens of minutes) events commonly associated with a Volcanic Eruption Index (VEI) of 2-3. Extrusion of viscous magma and the formation of a lava dome is often interspersed by short-lived vigorous (Vulcanian) explosions. The causes for and the timing of the transition from effusive to explosive activity during dome formation are poorly understood and forecasting this transition remains a challenge. Previous investigations have pointed towards pressure sources at shallow levels in volcanic conduits, which ultimately fuel Vulcanian explosions. Here, we describe and interpret a robust and unique multi-parameter data set documenting the subsurface processes associated with Vulcanian explosions at Soufriere Hills Volcano, Montserrat. We show that explosion priming can be driven by processes in the shallow or the deep magmatic system. The geophysical constraints on the eruption dynamics are consitent with the geological evidence of eruptive products. One geophysical signature is related exclusively to shallow dynamics including conduit destabilisation, syn-eruptive decompression and magma fragmentation, conduit emptying and expulsion of juvenile pumice. By contrast, another explosion was triggered by unprecedented sudden pressurisation of the entire plumbing system from depths of about 10 km resulting in the partial failure of the dome carapace, a violent cannon-like explosion, propagation of pressure waves and pronounced ballistic ejection of dome fragments. The timescale for explosion precursors is on the order of few minutes for both types of explosions, however, the precursory geophysical signatures are indicative of the nature of ensuing explosions. The short precursory phases characterise Vulcanian explosions as freak events

  5. Dynamical Signatures of Living Systems

    NASA Technical Reports Server (NTRS)

    Zak, M.

    1999-01-01

    One of the main challenges in modeling living systems is to distinguish a random walk of physical origin (for instance, Brownian motions) from those of biological origin and that will constitute the starting point of the proposed approach. As conjectured, the biological random walk must be nonlinear. Indeed, any stochastic Markov process can be described by linear Fokker-Planck equation (or its discretized version), only that type of process has been observed in the inanimate world. However, all such processes always converge to a stable (ergodic or periodic) state, i.e., to the states of a lower complexity and high entropy. At the same time, the evolution of living systems directed toward a higher level of complexity if complexity is associated with a number of structural variations. The simplest way to mimic such a tendency is to incorporate a nonlinearity into the random walk; then the probability evolution will attain the features of diffusion equation: the formation and dissipation of shock waves initiated by small shallow wave disturbances. As a result, the evolution never "dies:" it produces new different configurations which are accompanied by an increase or decrease of entropy (the decrease takes place during formation of shock waves, the increase-during their dissipation). In other words, the evolution can be directed "against the second law of thermodynamics" by forming patterns outside of equilibrium in the probability space. Due to that, a specie is not locked up in a certain pattern of behavior: it still can perform a variety of motions, and only the statistics of these motions is constrained by this pattern. It should be emphasized that such a "twist" is based upon the concept of reflection, i.e., the existence of the self-image (adopted from psychology). The model consists of a generator of stochastic processes which represents the motor dynamics in the form of nonlinear random walks, and a simulator of the nonlinear version of the diffusion

  6. Detection of signature volatiles for cariogenic microorganisms.

    PubMed

    Hertel, M; Preissner, R; Gillissen, B; Schmidt-Westhausen, A M; Paris, S; Preissner, S

    2016-02-01

    The development of a breath test by the identification of volatile organic compounds (VOCs) emitted by cariogenic bacteria is a promising approach for caries risk assessment and early caries detection. The aim of the present study was to investigate the volatile profiles of three major cariogenic bacteria and to assess whether the obtained signatures were species-specific. Therefore, the headspaces above cultures of Streptococcus mutans, Lactobacillus salivarius and Propionibacterium acidifaciens were analysed after 24 and 48 h of cultivation using gas chromatography and mass spectrometry. A volatile database was queried for the obtained VOC profiles. Sixty-four compounds were detected within the analysed culture headspaces and were absent (36) or at least only present in minor amounts (28) in the control headspace. For S. mutans 18, for L. salivarius three and for P. acidifaciens five compounds were found to be unique signature VOCs. Database matching revealed that the identified signatures of all bacteria were unique. Furthermore, 13 of the 64 detected substances have not been previously reported to be emitted by bacteria or fungi. Specific VOC signatures were found in all the investigated bacteria cultures. The obtained results encourage further research to investigate the transferability to in vivo conditions towards the development of a breath test. PMID:26610336

  7. Ankle and Other Signatures in Uhecr

    NASA Astrophysics Data System (ADS)

    Berezinsky, Veniamin

    2015-03-01

    The interaction signatures of UHE protons propagating through CMB are discussed. Much attention is given to ankle, which starting from 1963 is usually interpreted as a feature of transition from galactic to extragalactic cosmic rays. We argue here that this interpretation is now excluded. It gives more credit to alternative explanation of the ankle as an intrinsic part of the pair-production dip.

  8. Signatures of black holes at the LHC

    NASA Astrophysics Data System (ADS)

    Cavaglià, Marco; Godang, Romulus; Cremaldi, Lucien M.; Summers, Donald J.

    2007-06-01

    Signatures of black hole events at CERN's Large Hadron Collider are discussed. Event simulations are carried out with the Fortran Monte Carlo generator CATFISH. Inelasticity effects, exact field emissivities, color and charge conservation, corrections to semiclassical black hole evaporation, gravitational energy loss at formation and possibility of a black hole remnant are included in the analysis.

  9. Wave signatures in the Jovian magnetosphere

    NASA Astrophysics Data System (ADS)

    Petkaki, Panagiota; Dougherty, Michele

    2000-04-01

    Magnetometer data from the Ulysses Jupiter flyby are examined, in particular middle magnetosphere observations in the vicinity of the magnetodisk. Ion cyclotron waves are searched for in the heavy ion gyrofrequency regime (SO +2, SO +, K +, S +, Na +, O + and S ++). Power spectral peaks in the ion cyclotron frequency range from some of the dayside Ulysses magnetometer data have previously been described. Here we examine the dayside and high latitude duskside high resolution 1-s data. Ion cyclotron waves signatures are observed on several occasions both close to the magnetic equator and at some distance from it. Rippling and warping of the magnetodisk, as observed by Ulysses, could be the cause of such ion cyclotron signatures arising some distance away from the magnetic equator. Lower mass ions are observed further away from the planet and the heaviest mass ion signatures appear closer to the Io torus. Preliminary polarisation analysis of the observations is also presented and some theoretical implications of the wave signatures are discussed.

  10. Hyperspectral signature analysis of skin parameters

    NASA Astrophysics Data System (ADS)

    Vyas, Saurabh; Banerjee, Amit; Garza, Luis; Kang, Sewon; Burlina, Philippe

    2013-02-01

    The temporal analysis of changes in biological skin parameters, including melanosome concentration, collagen concentration and blood oxygenation, may serve as a valuable tool in diagnosing the progression of malignant skin cancers and in understanding the pathophysiology of cancerous tumors. Quantitative knowledge of these parameters can also be useful in applications such as wound assessment, and point-of-care diagnostics, amongst others. We propose an approach to estimate in vivo skin parameters using a forward computational model based on Kubelka-Munk theory and the Fresnel Equations. We use this model to map the skin parameters to their corresponding hyperspectral signature. We then use machine learning based regression to develop an inverse map from hyperspectral signatures to skin parameters. In particular, we employ support vector machine based regression to estimate the in vivo skin parameters given their corresponding hyperspectral signature. We build on our work from SPIE 2012, and validate our methodology on an in vivo dataset. This dataset consists of 241 signatures collected from in vivo hyperspectral imaging of patients of both genders and Caucasian, Asian and African American ethnicities. In addition, we also extend our methodology past the visible region and through the short-wave infrared region of the electromagnetic spectrum. We find promising results when comparing the estimated skin parameters to the ground truth, demonstrating good agreement with well-established physiological precepts. This methodology can have potential use in non-invasive skin anomaly detection and for developing minimally invasive pre-screening tools.

  11. 42 CFR 424.36 - Signature requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Signature requirements. 424.36 Section 424.36 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM CONDITIONS FOR MEDICARE PAYMENT Claims for Payment § 424.36...

  12. 76 FR 30542 - Adult Signature Services

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-26

    ... Signature labels are located in the Intelligent Mail Package Barcode Specification and the addendum to Publication 91, Addendum for Intelligent Mail Package Barcode (IMpb) and 3-digit Service Type Code, available... Intelligent Mail package barcode. * * * * * 3.0 Certified Mail * * * * * 3.2 Basic Information * * * * *...

  13. Exploring Signature Pedagogies in Undergraduate Leadership Education

    ERIC Educational Resources Information Center

    Jenkins, Daniel M.

    2012-01-01

    This research explores the instructional strategies most frequently used by leadership educators who teach academic credit-bearing undergraduate leadership studies courses through a national survey and identifies signature pedagogies within the leadership discipline. Findings from this study suggest that class discussion--whether in the form of…

  14. Modification of infrared signature of naval vessels

    NASA Astrophysics Data System (ADS)

    Milewski, S.; Dulski, R.; Kastek, M.; Trzaskawka, P.; Barela, J.; Firmanty, K.

    2012-06-01

    Every naval vessel can be detected and identified on the basis of its characteristics. The reduction of signature or matching it to the surrounding environment are one of the key tasks regarding survivability on a modern battlefield. The typical coatings applied on the outer surfaces of vessels are various kinds of paints. Their purpose is to protect the hull from aggressive sea environment and to provide camouflage in the visual spectrum as well as scatter and deflect microwave radiation. Apart from microwave and visual, infrared is most important spectral band used for detection purposes. In order to obtain effective protection in infrared the thermal signature of a vessel is required. It is determined on the basis of thermal contrast between a vessel itself and actual background and depends mostly on radiant properties of the hull. Such signature can be modified by altering apparent temperature values or the directions, in which the infrared radiation is emitted. The paper discusses selected methods of modification of vessel's infrared signature and effectiveness of infrared camouflage. Theoretical analyses were preceded by experimental measurements. The measurement-class infrared cameras and imaging spectroradiometers were used in order to determine the radiant exitance from different surface types. Experiments were conducted in selected conditions taking into account solar radiation and radiation reflected from elements of the surrounding scenery. Theoretical analysis took into account radiant angular properties of a vessel hull and attenuation of radiation after passing through the atmosphere. The study was performed in MWIR and LWIR ranges.

  15. The Pedagogic Signature of Special Needs Education

    ERIC Educational Resources Information Center

    Weiß, Sabine; Kollmannsberger, Markus; Lerche, Thomas; Oubaid, Viktor; Kiel, Ewald

    2014-01-01

    The goal of the following study is to identify a pedagogic signature, according to LS Shulman, for working with students who have special educational needs. Special educational needs are defined as significant limitations in personal development and learning which require particular educational measures beyond regular education. The development of…

  16. Negative obstacle detection by thermal signature

    NASA Technical Reports Server (NTRS)

    Matthies, Larry; Rankin, A.

    2003-01-01

    Detecting negative obstacles (ditches, potholes, and other depressions) is one of the most difficult problems in perception for autonomous, off-road navigation. Past work has largely relied on range imagery, because that is based on the geometry of the obstacle, is largely insensitive to illumination variables, and because there have not been other reliable alternatives. However, the visible aspect of negative obstacles shrinks rapidly with range, making them impossible to detect in time to avoid them at high speed. To relive this problem, we show that the interiors of negative obstacles generally remain warmer than the surrounding terrain throughout the night, making thermal signature a stable property for night-time negative obstacle detection. Experimental results to date have achieved detection distances 45% greater by using thermal signature than by using range data alone. Thermal signature is the first known observable with potential to reveal a deep negative obstacle without actually seeing far into it. Modeling solar illumination has potential to extend the usefulness of thermal signature through daylight hours.

  17. Quantum Signature Scheme with Weak Arbitrator

    NASA Astrophysics Data System (ADS)

    Luo, Ming-Xing; Chen, Xiu-Bo; Yun, Deng; Yang, Yi-Xian

    2012-07-01

    In this paper, we propose one quantum signature scheme with a weak arbitrator to sign classical messages. This scheme can preserve the merits in the original arbitrated scheme with some entanglement resources, and provide a higher efficiency in transmission and reduction the complexity of implementation. The arbitrator is costless and only involved in the disagreement case.

  18. Digital gene expression signatures for maize development

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Genome-wide expression signatures detect specific perturbations in developmental programs and contribute to functional resolution of key regulatory networks. In maize (Zea mays) inflorescences, mutations in the RAMOSA (RA) genes affect determinacy of axillary meristems and thus alter branching patt...

  19. Padlock and RCA signature predication software

    Energy Science and Technology Software Center (ESTSC)

    2005-10-24

    This software predicts DNA signatures compatible with padlock probe and rolling circle amplification (RCA) platforms. Specifically, the software takes a multiple sequence alignment, generates a consensus of conserved bases, and from these conserved regions selects forward and reverse primers that are immediately adjacent to one another, which is the desired orientation for assays such as padlock probes and RCA.

  20. MORPHOLOGICAL SIGNATURES AND GENOMIC CORRELATES IN GLIOBLASTOMA

    PubMed Central

    Cooper, Lee A.D.; Kong, Jun; Wang, Fusheng; Kurc, Tahsin; Moreno, Carlos S.; Brat, Daniel J.; Saltz, Joel H.

    2011-01-01

    Large multimodal datasets such as The Cancer Genome Atlas present an opportunity to perform correlative studies of tissue morphology and genomics to explore the morphological phenotypes associated with gene expression and genetic alterations. In this paper we present an investigation of Cancer Genome Atlas data that correlates morphology with recently discovered molecular subtypes of glioblastoma. Using image analysis to segment and extract features from millions of cells, we calculate high-dimensional morphological signatures to describe trends of nuclear morphology and cytoplasmic staining in whole-slide images. We illustrate the similarities between the analysis of these signatures and predictive studies of gene expression, both in terms of limited sample size and high-dimensionality. Our top-down analysis demonstrates the power of morphological signatures to predict clinically-relevant molecular tumor subtypes, with 85.4% recognition of the proneural subtype. A complementary bottom-up analysis shows that self-aggregating clusters have statistically significant associations with tumor subtype and reveals the existence of remarkable structure in the morphological signature space of glioblastomas. PMID:22183148

  1. The Los Alamos Science Pillars The Science of Signatures

    SciTech Connect

    Smith, Joshua E.; Peterson, Eugene J.

    2012-09-13

    As a national security science laboratory, Los Alamos is often asked to detect and measure the characteristics of complex systems and to use the resulting information to quantify the system's behavior. The Science of Signatures (SoS) pillar is the broad suite of technical expertise and capability that we use to accomplish this task. With it, we discover new signatures, develop new methods for detecting or measuring signatures, and deploy new detection technologies. The breadth of work at Los Alamos National Laboratory (LANL) in SoS is impressive and spans from the initial understanding of nuclear weapon performance during the Manhattan Project, to unraveling the human genome, to deploying laser spectroscopy instrumentation on Mars. Clearly, SoS is a primary science area for the Laboratory and we foresee that as it matures, new regimes of signatures will be discovered and new ways of extracting information from existing data streams will be developed. These advances will in turn drive the development of sensing instrumentation and sensor deployment. The Science of Signatures is one of three science pillars championed by the Laboratory and vital to supporting our status as a leading national security science laboratory. As with the other two pillars, Materials for the Future and Information Science and Technology for Predictive Science (IS&T), SoS relies on the integration of technical disciplines and the multidisciplinary science and engineering that is our hallmark to tackle the most difficult national security challenges. Over nine months in 2011 and 2012, a team of science leaders from across the Laboratory has worked to develop a SoS strategy that positions us for the future. The crafting of this strategy has been championed by the Chemistry, Life, and Earth Sciences Directorate, but as you will see from this document, SoS is truly an Institution-wide effort and it has engagement from every organization at the Laboratory. This process tapped the insight and

  2. Observational signatures of binary supermassive black holes

    SciTech Connect

    Roedig, Constanze; Krolik, Julian H.; Miller, M. Coleman

    2014-04-20

    Observations indicate that most massive galaxies contain a supermassive black hole, and theoretical studies suggest that when such galaxies have a major merger, the central black holes will form a binary and eventually coalesce. Here we discuss two spectral signatures of such binaries that may help distinguish them from ordinary active galactic nuclei. These signatures are expected when the mass ratio between the holes is not extreme and the system is fed by a circumbinary disk. One such signature is a notch in the thermal continuum that has been predicted by other authors; we point out that it should be accompanied by a spectral revival at shorter wavelengths and also discuss its dependence on binary properties such as mass, mass ratio, and separation. In particular, we note that the wavelength λ {sub n} at which the notch occurs depends on these three parameters in such a way as to make the number of systems displaying these notches ∝λ{sub n}{sup 16/3}; longer wavelength searches are therefore strongly favored. A second signature, first discussed here, is hard X-ray emission with a Wien-like spectrum at a characteristic temperature ∼100 keV produced by Compton cooling of the shock generated when streams from the circumbinary disk hit the accretion disks around the individual black holes. We investigate the observability of both signatures. The hard X-ray signal may be particularly valuable as it can provide an indicator of black hole merger a few decades in advance of the event.

  3. Infrared Signature Masking by Air Plasma Radiation

    NASA Technical Reports Server (NTRS)

    Kruger, C. H.; Laux, C. O.

    1998-01-01

    This report describes progress during the second year of our research program on Infrared Signature Masking by Air Plasmas at Stanford University. This program is intended to investigate the masking of infrared signatures by the air plasma formed behind the bow shock of high velocity missiles. Our previous annual report described spectral measurements and modeling of the radiation emitted between 3.2 and 5.5 microns by an atmospheric pressure air plasma in chemical and thermal equilibrium at a temperature of approximately 3100 K. One of our goals was to examine the spectral emission of secondary species such as water vapor or carbon dioxide. The cold air stream injected in the plasma torch contained approximately 330 parts per million Of CO2, which is the natural CO2 concentration in atmospheric air at room temperature, and a small amount of water vapor with an estimated mole fraction of 3.8 x 10(exp -4). As can be seen from Figure 1, it was found that the measured spectrum exhibited intense spectral features due to the fundamental rovibrational bands of NO at 4.9 - 5.5 microns and the V(3) band of CO2 (antisymmetric stretch) at 4.2-4.8 microns. These observations confirmed the well-known fact that infrared signatures between 4.15 - 5.5 microns can be masked by radiative emission in the interceptor's bow-shock. Figure I also suggested that the range 3.2 - 4.15 microns did not contain any significant emission features (lines or continuum) that could mask IR signatures. However, the signal-to-noise level, close to one in that range, precluded definite conclusions. Thus, in an effort to further investigate the spectral emission in the range of interest to signature masking problem, new measurements were made with a higher signal-to-noise ratio and an extended wavelength range.

  4. Infrasonic signature of the 2009 major sudden stratospheric warming

    NASA Astrophysics Data System (ADS)

    Evers, L. G.; Siegmund, P.

    2009-12-01

    The study of infrasound is experiencing a renaissance since it was chosen as a verification technique for the Comprehensive Nuclear-Test-Ban Treaty. The success of the verification technique strongly depends on knowledge of upper atmospheric processes. The ability of infrasound to probe the upper atmosphere starts to be exploited, taking the field beyond its monitoring application. Processes in the stratosphere couple to the troposphere and influence our daily weather and climate. Infrasound delivers actual observations on the state of the stratosphere with a high spatial and temporal resolution. Here we show the infrasonic signature, passively obtained, of a drastic change in the stratosphere due to the major sudden stratospheric warming (SSW) of January 2009. With this study, we infer the enormous capacity of infrasound in acoustic remote sensing of stratospheric processes on a global scale with surface based instruments.

  5. Effect of Weather on the Predicted PMN Landmine Chemical Signature for Kabul, Afghanistan

    SciTech Connect

    WEBB, STEPHEN W.; PHELAN, JAMES M.

    2002-11-01

    Buried landmines are often detected through the chemical signature in the air above the soil surface by mine detection dogs. Environmental processes play a significant role in the chemical signature available for detection. Due to the shallow burial depth of landmines, the weather influences the release of chemicals from the landmine, transport through the soil to the surface, and degradation processes in the soil. The effect of weather on the landmine chemical signature from a PMN landmine was evaluated with the T2TNT code for Kabul, Afghanistan. Results for TNT and DNT gas-phase and soil solid-phase concentrations are presented as a function of time of the day and time of the year.

  6. Multi-resolution and wavelet representations for identifying signatures of disease.

    PubMed

    Sajda, Paul; Laine, Andrew; Zeevi, Yehoshua

    2002-01-01

    Identifying physiological and anatomical signatures of disease in signals and images is one of the fundamental challenges in biomedical engineering. The challenge is most apparent given that such signatures must be identified in spite of tremendous inter and intra-subject variability and noise. Crucial for uncovering these signatures has been the development of methods that exploit general statistical properties of natural signals. The signal processing and applied mathematics communities have developed, in recent years, signal representations which take advantage of Gabor-type and wavelet-type functions that localize signal energy in a joint time-frequency and/or space-frequency domain. These techniques can be expressed as multi-resolution transformations, of which perhaps the best known is the wavelet transform. In this paper we review wavelets, and other related multi-resolution transforms, within the context of identifying signatures for disease. These transforms construct a general representation of signals which can be used in detection, diagnosis and treatment monitoring. We present several examples where these transforms are applied to biomedical signal and imaging processing. These include computer-aided diagnosis in mammography, real-time mosaicking of ophthalmic slit-lamp imagery, characterization of heart disease via ultrasound, predicting epileptic seizures and signature analysis of the electroencephalogram, and reconstruction of positron emission tomography data. PMID:14646044

  7. Mutation signatures of carcinogen exposure: genome-wide detection and new opportunities for cancer prevention

    PubMed Central

    2014-01-01

    Exposure to environmental mutagens is an important cause of human cancer, and measures to reduce mutagenic and carcinogenic exposures have been highly successful at controlling cancer. Until recently, it has been possible to connect the chemical characteristics of mutagens to actual mutations observed in human tumors only indirectly. Now, next-generation sequencing technology enables us to observe in detail the DNA-sequence-level effects of well-known mutagens, such as ultraviolet radiation and tobacco smoke, as well as endogenous mutagenic processes, such as those involving activated DNA cytidine deaminases (APOBECs). We can also observe the effects of less well-known but potent mutagens, including those recently found to be present in some herbal remedies. Crucially, we can now tease apart the superimposed effects of several mutational exposures and processes and determine which ones occurred during the development of individual tumors. Here, we review advances in detecting these mutation signatures and discuss the implications for surveillance and prevention of cancer. The number of sequenced tumors from diverse cancer types and multiple geographic regions is growing explosively, and the genomes of these tumors will bear the signatures of even more diverse mutagenic exposures. Thus, we envision development of wide-ranging compendia of mutation signatures from tumors and a concerted effort to experimentally elucidate the signatures of a large number of mutagens. This information will be used to link signatures observed in tumors to the exposures responsible for them, which will offer unprecedented opportunities for prevention. PMID:25031618

  8. Imaging Reservoir Quality: Seismic Signatures of Geologic Processes

    SciTech Connect

    Department of Geophysics

    2008-06-30

    Lithofacies successions from diverse depositional environments show distinctive patterns in various rock-physics planes (velocity-porosity, velocity-density and porosity-clay). Four clear examples of decameter-scale lithofacies sequences are documented in this study: (1) Micocene fluvial deposits show an inverted-V pattern indicative of dispersed fabric, (2) a fining-upward sequence of mud-rich deep deposits shows a linear trend associated with laminated sand-clay mixtures, (3) sand-rich deposits show a pattern resulting from the scarcity of mixed lithofacies, and (4) a coarsening-upward sequence shows evidence of both dispersed and horizontally laminated mixed lithofacies, with predominating dispersed mixtures generated by bioturbation. It was observed that carbonate-cemented sandstones are extremely heterogeneous in the project deep-water study area. Those from the base of incisions are usually associated with lower shaliness, lower porosity and higher P-impedance, while from the top of flooding surfaces exhibit higher shaliness, higher porosity and lower P-impedance. One rock physics model that captures the observed impedance-porosity trend is the 'stiff-sand model'. For this model, the high-porosity end-member is unconsolidated sand whose initial porosity is a function of sorting and shaliness, while the low-porosity end-member is solid mineral. These two end points are joined with a Hashin-Shtrikman equation. A systematic variation of quartz:clay ratio from proximal to distal locations was observed in the study area even within a single facies. The quartz:clay ratio changes from [0.5:0.5] to [1:0] along the direction of flow, based on the trends of P-impedance vs. porosity as predicted by the rock model for uncemented sands. The results are in agreement with spill-and-fill sequence stratigraphic model in mini-basin setting. In addition, porosity at the distal location ({approx}25 % to 35%) is higher than the porosity at the proximal location ({approx}20 % to 23%). This trend is explained by a sequence stratigraphic model which predicts progressive increase in sorting by turbidity current along the flow, as well as, quantified by a rock model that heuristically accounts for sorting. The results can be applied to improve quantitative predication of sediment parameters from seismic impedance, away from well locations.

  9. Core Formation Under Dynamic Conditions: Physical Processes and Geochemical Signatures

    NASA Technical Reports Server (NTRS)

    Rushmer, T.; Gaetani, G.; Jones, J. H.; Sparks, J.

    2001-01-01

    We have experimentally investigated liquid metal segregation from a solid silicate matrix under conditions of applied stress. Liquid moves in fractures and formation of fayalitic olivine from orthopyroxene by migrating Fe-Ni-S-O liquids is observed. Additional information is contained in the original extended abstract.

  10. Methods and apparatus for multi-parameter acoustic signature inspection

    DOEpatents

    Diaz, Aaron A.; Samuel, Todd J.; Valencia, Juan D.; Gervais, Kevin L.; Tucker, Brian J.; Kirihara, Leslie J.; Skorpik, James R.; Reid, Larry D.; Munley, John T.; Pappas, Richard A.; Wright, Bob W.; Panetta, Paul D.; Thompson, Jason S.

    2007-07-24

    A multiparameter acoustic signature inspection device and method are described for non-invasive inspection of containers. Dual acoustic signatures discriminate between various fluids and materials for identification of the same.

  11. Loop-Mediated Isothermal Amplification (LAMP) Signature Identification Software

    Energy Science and Technology Software Center (ESTSC)

    2009-03-17

    This is an extendable open-source Loop-mediated isothermal AMPlification (LAMP) signature design program called LAVA (LAMP Assay Versatile Analysis). LAVA was created in response to limitations of existing LAMP signature programs.

  12. Forward secure digital signature for electronic medical records.

    PubMed

    Yu, Yao-Chang; Huang, To-Yeh; Hou, Ting-Wei

    2012-04-01

    The Technology Safeguard in Health Insurance Portability and Accountability Act (HIPAA) Title II has addressed a way to maintain the integrity and non-repudiation of Electronic Medical Record (EMR). One of the important cryptographic technologies is mentioned in the ACT is digital signature; however, the ordinary digital signature (e.g. DSA, RSA, GQ...) has an inherent weakness: if the key (certificate) is updated, than all signatures, even the ones generated before the update, are no longer trustworthy. Unfortunately, the current most frequently used digital signature schemes are categorized into the ordinary digital signature scheme; therefore, the objective of this paper is to analyze the shortcoming of using ordinary digital signatures in EMR and to propose a method to use forward secure digital signature to sign EMR to ensure that the past EMR signatures remain trustworthy while the key (certificate) is updated. PMID:20703711

  13. Exobiology and the search for biological signatures on Mars

    NASA Technical Reports Server (NTRS)

    Mancinelli, Rocco L.; Schwartz, Deborah E.

    1988-01-01

    In preparation for a Mars Rover/Sample return mission, the mission goals and objectives must be identified. One of the most important objectives must address exobiology and the question of the possibility of the origin and evolution of life on Mars. In particular, key signatures or bio-markers of a possible extinct Martian biota must be defined. To that end geographic locations (sites) that are likely to contain traces of past life must also be identified. Sites and experiments are being defined in support of a Mars rover sample return mission. In addition, analyses based on computer models of abiotic processes of CO2 loss from Mars suggest that the CO2 from the atmosphere may have precipitated as carbonates and be buried within the Martian regolith. The carbon cycle of perennially frozen lakes in the dry valley of Antarctica are currently being investigated. These lakes were purported to be a model system for the ancient Martian lakes. By understanding the dynamic balance between the abiotic vs. biotic cycling of carbon within this system, information is gathered which will enable the interpretation of data obtained by a Mars rover with respect to possible carbonate deposits and the processing of carbon by biological systems. These ancient carbonate deposits, and other sedimentary units would contain traces of biological signatures that would hold the key to understanding the origin and evolution of life on Mars, as well as Earth.

  14. Emerging landscape of oncogenic signatures across human cancers

    PubMed Central

    Ciriello, Giovanni; Miller, Martin L; Aksoy, Bülent Arman; Senbabaoglu, Yasin; Schultz, Nikolaus; Sander, Chris

    2014-01-01

    Cancer therapy is challenged by the diversity of molecular implementations of oncogenic processes and by the resulting variation in therapeutic responses. Projects such as The Cancer Genome Atlas (TCGA) provide molecular tumor maps in unprecedented detail. The interpretation of these maps remains a major challenge. Here we distilled thousands of genetic and epigenetic features altered in cancers to ~500 selected functional events (SFEs). Using this simplified description, we derived a hierarchical classification of 3,299 TCGA tumors from 12 cancer types. The top classes are dominated by either mutations (M class) or copy number changes (C class). This distinction is clearest at the extremes of genomic instability, indicating the presence of different oncogenic processes. The full hierarchy shows functional event patterns characteristic of multiple cross-tissue groups of tumors, termed oncogenic signature classes. Targetable functional events in a tumor class are suggestive of class-specific combination therapy. These results may assist in the definition of clinical trials to match actionable oncogenic signatures with personalized therapies. PMID:24071851

  15. Condition monitoring of machinery using motor current signature analysis

    SciTech Connect

    Kryter, R.C.; Haynes, H.D.

    1989-01-01

    Motor current signature analysis (MCSA) is a powerful monitoring tool for motor-driven equipment that provides a nonintrusive means for detecting the presence of mechanical and electrical abnormalities in the motor and the driven equipment, including altered conditions in the process ''downstream'' of the motor-driven equipment. It was developed at the Oak Ridge National Laboratory as a means for determining the effects of aging and service wear systems, but it is applicable to a broad range of machinery. MCSA is based on the recognition that an electric motor (ac or dc) driving a mechanical load acts as an efficient and permanently available transducer by sensing mechanical load variations, large and small, long-term and rapid, and converting them into variations in the induced current generated in the motor windings. These motor current variations are carried by the electrical cables processes as desired. Motor current signatures, obtained in both time and over time to provide early indication of degradation. Successful applications of MCSA technology (patent applied for) include not only motor-operated valves but also pumps of various designs, blowers, and air conditioning systems. Examples are presented briefly, and speculation regarding the applicability of MCSA to a broader range of equipment monitoring and production line testing is also given. 1 ref., 13 figs.

  16. Landscape cultivation alters δ30Si signature in terrestrial ecosystems

    NASA Astrophysics Data System (ADS)

    Vandevenne, Floor; Delvaux, Claire; Hughes, Harold; Ronchi, Benedicta; Clymans, Wim; Barao, Ana Lucia; Govers, Gerard; Cornelis, Jean Thomas; André, Luc; Struyf, Eric

    2015-04-01

    Despite increasing recognition of the importance of biological Si cycling in controlling dissolved Si (DSi) in soil and stream water, effects of human cultivation on the Si cycle remain poorly understood. Sensitive tracer techniques to identify and quantify Si in the soil-plant-water system could be highly relevant in addressing these uncertainties. Stable Si isotopes are promising tools to define Si sources and sinks along the ecosystem flow path, as intense fractionation occurs during chemical weathering and uptake of dissolved Si in plants. Yet they remain underexploited in the end product of the soil-plant system: the soil water. Here, stable Si isotope ratios (δ30Si) of dissolved Si in soil water were measured along a land use gradient (continuous forest, continuous pasture, young cropland and continuous cropland) with similar parent material (loess) and homogenous bulk mineralogical and climatological (Belgium). Soil water δ30Si signatures are clearly separated along the gradient, with highest average signatures in continuous cropland (+1.61%), intermediate in pasture (+1.05%) and young cropland (+0.89%) and lowest in forest soil water (+0.62%). Our data do not allow distinguishing biological from pedogenic/lithogenic processes, but point to a strong interaction of both. We expect that increasing export of light isotopes in disturbed land uses (i.e. through agricultural harvest), and higher recycling of 28Si and elevated weathering intensity (including clay dissolution) in forest systems will largely determine soil water δ30Si signatures of our systems. Our results imply that soil water δ30Si signature is biased through land management before it reaches rivers and coastal zones, where other fractionation processes take over (e.g. diatom uptake and reverse weathering in floodplains). In particular, a direct role of agriculture systems in lowering export Si fluxes towards rivers and coastal systems has been shown. Stable Si isotopes have a large potential

  17. Landscape cultivation alters δ30Si signature in terrestrial ecosystems.

    NASA Astrophysics Data System (ADS)

    Vandevenne, F. I.; Delvaux, C.; Huyghes, H.; Ronchi, B.; Govers, G.; Barão, A. L.; Clymans, W.; Meire, P.; André, L.; Struyf, E.

    2014-12-01

    Despite increasing recognition of the importance of biological Si cycling in controlling dissolved Si (DSi) in soil and stream water, effects of human cultivation on the Si cycle remain poorly understood. Sensitive tracer techniques to identify and quantify Si in the soil-plant-water system could be highly relevant in addressing these uncertainties. Stable Si isotopes are promising tools to define Si sources and sinks along the ecosystem flow path, as intense fractionation occurs during chemical weathering and uptake of dissolved Si in plants. Yet they remain underexploited in the end product of the soil-plant system: the soil water. Here, stable Si isotope ratios (δ30Si) of dissolved Si in soil water were measured along a land use gradient (continuous forest, continuous pasture, young cropland and continuous cropland) with similar parent material (loess) and homogenous bulk mineralogical and climatological properties (Belgium). Soil water δ30Si signatures are clearly separated along the gradient, with highest average signatures in continuous cropland (+1.61‰), intermediate in pasture (+1.05‰) and young cropland (+0.89 ‰) and lowest in forest soil water (+0.62‰). Our data do not allow distinguishing biological from pedogenic/lithogenic processes, but point to a strong interaction of both. We expect that increasing export of light isotopes in disturbed land uses (i.e. through agricultural harvest), and higher recycling of 28Si and elevated weathering intensity (including clay dissolution) in forest systems will largely determine soil water δ30Si signatures of our systems. Our results imply that soil water δ30Si signature is biased through land management before it reaches rivers and coastal zones, where other fractionation processes take over (e.g. diatom uptake and reverse weathering in floodplains). In particular, a direct role of agriculture systems in lowering export Si fluxes towards rivers and coastal systems has been shown. Stable Si isotopes have

  18. Process

    SciTech Connect

    Geenen, P.V.; Bennis, J.

    1989-04-04

    A process is described for minimizing the cracking tendency and uncontrolled dimensional change, and improving the strength of a rammed plastic refractory reactor liner comprising phosphate-bonded silicon carbide or phosphate-bonded alumina. It consists of heating the reactor liner placed or mounted in a reactor, prior to its first use, from ambient temperature up to a temperature of from about 490/sup 0/C to about 510/sup 0/C, the heating being carried out by heating the liner at a rate to produce a temperature increase of the liner not greater than about 6/sup 0/C per hour.

  19. Spectral induced polarization signature of contaminated soil

    NASA Astrophysics Data System (ADS)

    Schwartz, N.; Huisman, J. A.; Shefer, I.; Furman, A.

    2012-04-01

    Spectral induced polarization (SIP) signatures of porous media contaminated with non aqueous phase liquids (NAPL) were measured using an accurate impedance meter. The samples were prepared by mixing air-dried sand with 15% by weight of bentonite clay, tap water and either diesel fuel or motor oil. Next, the soil was packed in a column and left for 24 hr before electrical measurements were performed. For all the samples, water saturation was constant (Sw = 0.47) and the NAPL saturation was 0 (control), 5, or 15 percent. Counter-intuitively, the results show that addition of NAPL to the porous media resulted in an increase of the real part of the complex conductivity. Evidently, for each type of contaminant, an increase in the contaminant saturation resulted in an increase in the real part of the conductivity. The imaginary part of the complex conductivity showed a reversed behavior: higher NAPL saturation resulted in a reduction of the imaginary part of the complex conductivity. For both the real and the imaginary part of the complex conductivity, the effect of NAPL on the complex electrical conductivity was more significant for motor oil than for diesel fuel. In addition to the electrical measurements, we also performed an extraction experiment to examine the effect of the presence of NAPL on the electrical conductivity (EC) of the pore water. The results from the extraction experiment showed that addition of NAPL to the porous media resulted in an increase of the pore water EC. We argue that this increase in the real part of the complex conductivity is related to adsorption of organic polar compounds from the NAPL onto the mineral surface and the associated release of inorganic ions from the mineral surface to the pore water. These exchange processes affect both the surface and the pore water conductivity. In addition, we suggest that the decrease in polarization (associated with the imaginary part of the complex conductivity) of the NAPL contaminated porous media

  20. Brain oscillatory signatures of motor tasks

    PubMed Central

    Birbaumer, Niels

    2015-01-01

    Noninvasive brain-computer-interfaces (BCI) coupled with prosthetic devices were recently introduced in the rehabilitation of chronic stroke and other disorders of the motor system. These BCI systems and motor rehabilitation in general involve several motor tasks for training. This study investigates the neurophysiological bases of an EEG-oscillation-driven BCI combined with a neuroprosthetic device to define the specific oscillatory signature of the BCI task. Controlling movements of a hand robotic orthosis with motor imagery of the same movement generates sensorimotor rhythm oscillation changes and involves three elements of tasks also used in stroke motor rehabilitation: passive and active movement, motor imagery, and motor intention. We recorded EEG while nine healthy participants performed five different motor tasks consisting of closing and opening of the hand as follows: 1) motor imagery without any external feedback and without overt hand movement, 2) motor imagery that moves the orthosis proportional to the produced brain oscillation change with online proprioceptive and visual feedback of the hand moving through a neuroprosthetic device (BCI condition), 3) passive and 4) active movement of the hand with feedback (seeing and feeling the hand moving), and 5) rest. During the BCI condition, participants received contingent online feedback of the decrease of power of the sensorimotor rhythm, which induced orthosis movement and therefore proprioceptive and visual information from the moving hand. We analyzed brain activity during the five conditions using time-frequency domain bootstrap-based statistical comparisons and Morlet transforms. Activity during rest was used as a reference. Significant contralateral and ipsilateral event-related desynchronization of sensorimotor rhythm was present during all motor tasks, largest in contralateral-postcentral, medio-central, and ipsilateral-precentral areas identifying the ipsilateral precentral cortex as an integral

  1. The nature of spectral signatures in native arid plant communities

    NASA Technical Reports Server (NTRS)

    Conn, J. S.; Foster, K. E.; Mcginnies, W. G.

    1976-01-01

    Radiometric data in ERTS bands 5 and 7 of spectral signature components were compared to the overall signatures obtained from an airborne radiometric data collection system flown at low altitude. Results indicate that due to the low density and low vigor of the vegetation, vegetation has little effect on the overall signature, thus making differentiation of desert plant communities on the basis of spectral signature extremely difficult.

  2. Signature modelling and radiometric rendering equations in infrared scene simulation systems

    NASA Astrophysics Data System (ADS)

    Willers, Cornelius J.; Willers, Maria S.; Lapierre, Fabian

    2011-11-01

    The development and optimisation of modern infrared systems necessitates the use of simulation systems to create radiometrically realistic representations (e.g. images) of infrared scenes. Such simulation systems are used in signature prediction, the development of surveillance and missile sensors, signal/image processing algorithm development and aircraft self-protection countermeasure system development and evaluation. Even the most cursory investigation reveals a multitude of factors affecting the infrared signatures of realworld objects. Factors such as spectral emissivity, spatial/volumetric radiance distribution, specular reflection, reflected direct sunlight, reflected ambient light, atmospheric degradation and more, all affect the presentation of an object's instantaneous signature. The signature is furthermore dynamically varying as a result of internal and external influences on the object, resulting from the heat balance comprising insolation, internal heat sources, aerodynamic heating (airborne objects), conduction, convection and radiation. In order to accurately render the object's signature in a computer simulation, the rendering equations must therefore account for all the elements of the signature. In this overview paper, the signature models, rendering equations and application frameworks of three infrared simulation systems are reviewed and compared. The paper first considers the problem of infrared scene simulation in a framework for simulation validation. This approach provides concise definitions and a convenient context for considering signature models and subsequent computer implementation. The primary radiometric requirements for an infrared scene simulator are presented next. The signature models and rendering equations implemented in OSMOSIS (Belgian Royal Military Academy), DIRSIG (Rochester Institute of Technology) and OSSIM (CSIR & Denel Dynamics) are reviewed. In spite of these three simulation systems' different application focus

  3. Merger Signatures in the Dynamics of Star-forming Gas

    NASA Astrophysics Data System (ADS)

    Hung, Chao-Ling; Hayward, Christopher C.; Smith, Howard A.; Ashby, Matthew L. N.; Lanz, Lauranne; Martínez-Galarza, Juan R.; Sanders, D. B.; Zezas, Andreas

    2016-01-01

    The recent advent of integral field spectrographs and millimeter interferometers has revealed the internal dynamics of many hundreds of star-forming galaxies. Spatially resolved kinematics have been used to determine the dynamical status of star-forming galaxies with ambiguous morphologies, and constrain the importance of galaxy interactions during the assembly of galaxies. However, measuring the importance of interactions or galaxy merger rates requires knowledge of the systematics in kinematic diagnostics and the visible time with merger indicators. We analyze the dynamics of star-forming gas in a set of binary merger hydrodynamic simulations with stellar mass ratios of 1:1 and 1:4. We find that the evolution of kinematic asymmetries traced by star-forming gas mirrors morphological asymmetries derived from mock optical images, in which both merger indicators show the largest deviation from isolated disks during strong interaction phases. Based on a series of simulations with various initial disk orientations, orbital parameters, gas fractions, and mass ratios, we find that the merger signatures are visible for ˜0.2-0.4 Gyr with kinematic merger indicators but can be approximately twice as long for equal-mass mergers of massive gas-rich disk galaxies designed to be analogs of z ˜ 2-3 submillimeter galaxies. Merger signatures are most apparent after the second passage and before the black holes coalescence, but in some cases they persist up to several hundred Myr after coalescence. About 20%-60% of the simulated galaxies are not identified as mergers during the strong interaction phase, implying that galaxies undergoing violent merging process do not necessarily exhibit highly asymmetric kinematics in their star-forming gas. The lack of identifiable merger signatures in this population can lead to an underestimation of merger abundances in star-forming galaxies, and including them in samples of star-forming disks may bias the measurements of disk properties such

  4. 17 CFR 1.4 - Use of electronic signatures.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false Use of electronic signatures... REGULATIONS UNDER THE COMMODITY EXCHANGE ACT Definitions § 1.4 Use of electronic signatures. For purposes of... pool participant or a client of a commodity trading advisor, an electronic signature executed by...

  5. 40 CFR 263.25 - Electronic manifest signatures.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 26 2014-07-01 2014-07-01 false Electronic manifest signatures. 263.25 Section 263.25 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... Recordkeeping § 263.25 Electronic manifest signatures. (a) Electronic manifest signatures shall meet...

  6. 17 CFR 1.4 - Use of electronic signatures.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Use of electronic signatures... REGULATIONS UNDER THE COMMODITY EXCHANGE ACT Definitions § 1.4 Use of electronic signatures. For purposes of... broker, a pool participant or a client of a commodity trading advisor, an electronic signature...

  7. 17 CFR 1.4 - Use of electronic signatures.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 1 2011-04-01 2011-04-01 false Use of electronic signatures... REGULATIONS UNDER THE COMMODITY EXCHANGE ACT Definitions § 1.4 Use of electronic signatures. For purposes of... pool participant or a client of a commodity trading advisor, an electronic signature executed by...

  8. 17 CFR 201.65 - Identity and signature.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Identity and signature. 201.65... of 1934 § 201.65 Identity and signature. Applications pursuant to this subpart may omit the identity, mailing address, and signature of the applicant; provided, that such identity, mailing address...

  9. 45 CFR 81.32 - Signature of documents.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Signature of documents. 81.32 Section 81.32 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION PRACTICE AND PROCEDURE FOR HEARINGS UNDER PART 80 OF THIS TITLE Form, Execution, Service and Filing of Documents § 81.32 Signature of documents. The signature of a...

  10. Analysis of parameters probability on Zhang-Wang signature scheme

    NASA Astrophysics Data System (ADS)

    Yang, Weiping; Liu, Chenglian

    2014-10-01

    Zhang and Wang proposed an improved signature scheme without using one-way hash functions. In this paper, we analyze the odd and even probability of signature parameters in Zhang-Wang signature scheme, which combined with Boolean algebra, such as bitwise exclusive-or (XOR). Furthermore, it is pointed out that we can use them for attacks.

  11. mRNA Expression Signature of Gleason Grade Predicts Lethal Prostate Cancer

    PubMed Central

    Penney, Kathryn L.; Sinnott, Jennifer A.; Fall, Katja; Pawitan, Yudi; Hoshida, Yujin; Kraft, Peter; Stark, Jennifer R.; Fiorentino, Michelangelo; Perner, Sven; Finn, Stephen; Calza, Stefano; Flavin, Richard; Freedman, Matthew L.; Setlur, Sunita; Sesso, Howard D.; Andersson, Swen-Olof; Martin, Neil; Kantoff, Philip W.; Johansson, Jan-Erik; Adami, Hans-Olov; Rubin, Mark A.; Loda, Massimo; Golub, Todd R.; Andrén, Ove; Stampfer, Meir J.; Mucci, Lorelei A.

    2011-01-01

    Purpose Prostate-specific antigen screening has led to enormous overtreatment of prostate cancer because of the inability to distinguish potentially lethal disease at diagnosis. We reasoned that by identifying an mRNA signature of Gleason grade, the best predictor of prognosis, we could improve prediction of lethal disease among men with moderate Gleason 7 tumors, the most common grade, and the most indeterminate in terms of prognosis. Patients and Methods Using the complementary DNA–mediated annealing, selection, extension, and ligation assay, we measured the mRNA expression of 6,100 genes in prostate tumor tissue in the Swedish Watchful Waiting cohort (n = 358) and Physicians' Health Study (PHS; n = 109). We developed an mRNA signature of Gleason grade comparing individuals with Gleason ≤ 6 to those with Gleason ≥ 8 tumors and applied the model among patients with Gleason 7 to discriminate lethal cases. Results We built a 157-gene signature using the Swedish data that predicted Gleason with low misclassification (area under the curve [AUC] = 0.91); when this signature was tested in the PHS, the discriminatory ability remained high (AUC = 0.94). In men with Gleason 7 tumors, who were excluded from the model building, the signature significantly improved the prediction of lethal disease beyond knowing whether the Gleason score was 4 + 3 or 3 + 4 (P = .006). Conclusion Our expression signature and the genes identified may improve our understanding of the de-differentiation process of prostate tumors. Additionally, the signature may have clinical applications among men with Gleason 7, by further estimating their risk of lethal prostate cancer and thereby guiding therapy decisions to improve outcomes and reduce overtreatment. PMID:21537050

  12. A Nucleotide Signature for the Identification of American Ginseng and Its Products

    PubMed Central

    Liu, Yang; Wang, Xiaoyue; Wang, Lili; Chen, Xiaochen; Pang, Xiaohui; Han, Jianping

    2016-01-01

    American ginseng (derived from Panax quinquefolius) is one of the most widely used medicinal herbs in the world. Because of its high price and increasing demand, there are many adulterants on the market. The proposed internal transcribed spacer 2 (ITS2) has been used to identify raw medicinal materials, but it is not suitable for the identification of Chinese patent medicine ingredients. Therefore, a short barcode for the identification of processed American ginseng and its corresponding Chinese patent medicines would be profitable. In this study, 94 samples of American ginseng and Asian ginseng were collected from all over the world. The ITS2 region was sequenced, and a nucleotide signature was developed based on one single nucleotide polymorphism (SNP) site unique to American ginseng. The nucleotide signature (atcactcctt tgcgggagtc gaggcgg) consists of 27 bases over the length of the ITS2 sequence (420 bp). Furthermore, we also designed primer pairs to amplify the nucleotide signature; the specific primer pair 4F/4R has been found to be unique to the ginseng species and capable of amplifying the nucleotide signatures from Chinese patent medicines and decoctions. We used the nucleotide signature method to inspect ginseng products in Chinese patent medicines; 24 batches of Chinese patent medicine from stores in Beijing were amplified and sequenced successfully. Using the double peaks at the SNP sites of the nucleotide signature, 5 batches were found to be counterfeits, and 2 batches were found to contain adulterants. Thus, this nucleotide signature, with only 27 bp, has broadened the application of DNA barcoding in identification of decoctions, Chinese patent medicines and other ginseng products with degraded DNA. This method can rapidly identify ginseng products and could also be developed as an on-site detection method. PMID:27047504

  13. Collider signature of T-quarks

    SciTech Connect

    Carena, Marcela; Hubisz, Jay; Perelstein, Maxim; Verdier, Patrice; /Lyon, IPN

    2006-10-01

    Little Higgs models with T Parity contain new vector-like fermions, the T-odd quarks or ''T-quarks'', which can be produced at hadron colliders with a QCD-strength cross section. Events with two acoplanar jets and large missing transverse energy provide a simple signature of T-quark production. We show that searches for this signature with the Tevatron Run II data can probe a significant part of the Little Higgs model parameter space not accessible to previous experiments, exploring T-quark masses up to about 400 GeV. This reach covers parts of the parameter space where the lightest T-odd particle can account for the observed dark matter relic abundance. We also comment on the prospects for this search at the Large Hadron Collider (LHC).

  14. GEM Workshop on Intercalibrating Cusp Signatures

    NASA Astrophysics Data System (ADS)

    On October 9, 1990, a lively group of more than 60 scientists from around the world gathered at Northeastern University's Henderson House in Weston, Mass., to spend 4 days in concentrated efforts to unravel the complexities of cusp/cleft theory and observations.Plans for the National Science Foundation-sponsored workshop were formulated at the previous GEM workshop convened by Ted Rosenberg at the University of Maryland in October 1989, where participants agreed that the first task of the first GEM campaign—attacking problems of the magnetopause, boundary layers, and their signatures in the ionosphere—should be the identification of cusp signatures in ground-based and airborne data by intercalibrating with spacecraft data on direct overflights.

  15. Soil signature simulation in the thermal infrared

    NASA Astrophysics Data System (ADS)

    Carson, Tyler; Salvaggio, Carl

    2015-10-01

    Soil emissivity signatures were constructed using the digital imaging and remote sensing image generation (DIRSIG) model and Blender three-dimensional (3-D) graphic design software. Using these tools, the geometry, radiometry, and chemistry of quartz were exploited to model the presence of particle size effects in the thermal spectra of disturbed soil. Using the physics engines within the Blender 3-D graphic design software, a physical representation of a granular soil scene was created. Chemical and optical properties of pure quartz were assigned to particles in the scene based on particle size. The spectral signature of disturbed soil was modeled by the physical mixture of small fine particles (50 μm diameter) and larger grains (500 μm diameter). The study demonstrated that by combining realistic target geometry and spectral measurements of pure quartz, emissivity of complex soil mixtures could be modeled without functional data fitting or rigorous analysis of material dynamics.

  16. Infrared signature evolution of a CUBI

    NASA Astrophysics Data System (ADS)

    van Iersel, M.; van Eijk, A. M. J.; Veerman, H. E. T.; Benoist, K. W.; Cohen, L. H.

    2015-09-01

    A CUBI, a simple geometric metal test-object, is placed in an outdoor environment to monitor the infrared signature. The (daily) temperature evolution of the individual facets is monitored as function of environmental parameters, such as solar irradiance and ambient temperature. This provides insight in the parameters that have the strongest effects on the thermal signature of the CUBI. The CUBI is also imaged by infrared cameras and these recordings are used to estimate the temperature of the CUBI. The recorded images are also used to provide insight in the amount of air turbulence generated by the radiance of the hot CUBI facets. The amount of turbulence is compared with the ambient turbulence as calculated by standard bulk theories.

  17. Vibration signature analysis of multistage gear transmission

    NASA Technical Reports Server (NTRS)

    Choy, F. K.; Tu, Y. K.; Savage, M.; Townsend, D. P.

    1989-01-01

    An analysis is presented for multistage multimesh gear transmission systems. The analysis predicts the overall system dynamics and the transmissibility to the gear box or the enclosed structure. The modal synthesis approach of the analysis treats the uncoupled lateral/torsional model characteristics of each stage or component independently. The vibration signature analysis evaluates the global dynamics coupling in the system. The method synthesizes the interaction of each modal component or stage with the nonlinear gear mesh dynamics and the modal support geometry characteristics. The analysis simulates transient and steady state vibration events to determine the resulting torque variations, speeds, changes, rotor imbalances, and support gear box motion excitations. A vibration signature analysis examines the overall dynamic characteristics of the system, and the individual model component responses. The gear box vibration analysis also examines the spectral characteristics of the support system.

  18. Gene Signatures in Hepatocellular Carcinoma (HCC)

    PubMed Central

    Studach, Leo; Merle, Philippe

    2010-01-01

    Primary hepatocellular carcinoma (HCC) is a significant human cancer globally, with poor prognosis. New and efficacious therapy strategies are needed as well as new biomarkers for early detection of at-risk patients. In this review, we discuss select microarray studies of human HCCs, and propose a gene signature that has promise for clinical/translational application. This gene signature combines the proliferation cluster of genes and the hepatic cancer initiating/stem cell gene cluster for identification of HCCs with poor prognosis. Evidence from cell-based assays identifies the existence of a mechanistic link between these two gene clusters, involving the proliferation cluster gene Polo-like kinase 1 (PLK1). We propose that PLK1 is a promising therapy target for HCC. PMID:20851183

  19. Infra-sound Signature of Lightning

    NASA Astrophysics Data System (ADS)

    Arechiga, R. O.; Badillo, E.; Johnson, J.; Edens, H. E.; Rison, W.; Thomas, R. J.

    2012-12-01

    We have analyzed thunder from over 200 lightning flashes to determine which part of thunder comes from the gas dynamic expansion of portions of the rapidly heated lightning channel and which from electrostatic field changes. Thunder signals were recorded by a ~1500 m network of 3 to 4 4-element microphone deployed in the Magdalena mountains of New Mexico in the summers of 2011 and 2012. The higher frequency infra-sound and audio-range portion of thunder is thought to come from the gas dynamic expansion, and the electrostatic mechanism gives rise to a signature infra-sound pulse peaked at a few Hz. More than 50 signature infra-sound pulses were observed in different portions of the thunder signal, with no preference towards the beginning or the end of the signal. Detection of the signature pulse occurs sometimes only for one array and sometimes for several arrays, which agrees with the theory that the pulse is highly directional (i.e., the recordings have to be in a specific position with respect to the cloud generating the pulse to be able to detect it). The detection of these pulses under quiet wind conditions by different acoustic arrays corroborates the electrostatic mechanism originally proposed by Wilson [1920], further studied by Dessler [1973] and Few [1985], observed by Bohannon [1983] and Balachandran [1979, 1983], and recently analyzed by Pasko [2009]. Pasko employed a model to explain the electrostatic-to-acoustic energy conversion and the initial compression waves in observed infrasonic pulses, which agrees with the observations we have made. We present thunder samples that exhibit signature infra-sound pulses at different times and acoustic source reconstruction to demonstrate the beaming effect.

  20. Cryptanalysis of fair quantum blind signatures

    NASA Astrophysics Data System (ADS)

    He, Li-Bao; Huang, Liu-Sheng; Yang, Wei; Xu, Rui

    2012-03-01

    We investigate the fair quantum blind signature scheme proposed by Wang and Wen [Wang T Y and Wen Q Y 2010 Chin. Phys. B 19 060307], which uses the fundamental properties of quantum mechanics and the availability of a trusted arbitrator. However, in this paper, we find that the protocol cannot satisfy the property of non-forgeability even under the condition that the trusted arbitrator is totally credible. Moreover, a simple feasible suggestion for improving the protocol is proposed.

  1. Constraining blazar physics with polarization signatures

    NASA Astrophysics Data System (ADS)

    Zhang, Haocheng; Boettcher, Markus; Li, Hui

    2016-01-01

    Blazars are active galactic nuclei whose jets are directed very close to our line of sight. They emit nonthermal-dominated emission from radio to gamma-rays, with the radio to optical emissions known to be polarized. Both radiation and polarization signatures can be strongly variable. Observations have shown that sometimes strong multiwavelength flares are accompanied by drastic polarization variations, indicating active participation of the magnetic field during flares. We have developed a 3D multi-zone time-dependent polarization-dependent radiation transfer code, which enables us to study the spectral and polarization signatures of blazar flares simultaneously. By combining this code with a Fokker-Planck nonthermal particle evolution scheme, we are able to derive simultaneous fits to time-dependent spectra, multiwavelength light curves, and time-dependent optical polarization signatures of a well-known multiwavelength flare with 180 degree polarization angle swing of the blazar 3C279. Our work shows that with detailed consideration of light travel time effects, the apparently symmetric time-dependent radiation and polarization signatures can be naturally explained by a straight, helically symmetric jet pervaded by a helical magnetic field, without the need of any asymmetric structures. Also our model suggests that the excess in the nonthermal particles during flares can originate from magnetic reconnection events, initiated by a shock propagating through the emission region. Additionally, the magnetic field should generally revert to its initial topology after the flare. We conclude that such shock-initiated magnetic reconnection event in an emission environment with relatively strong magnetic energy can be the driver of multiwavelength flares with polarization angle swings. Future statistics on such observations will constrain general features of such events, while magneto-hydrodynamic simulations will provide physical scenarios for the magnetic field evolution

  2. 27 CFR 73.11 - What are the required components and controls for acceptable electronic signatures?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... signatures not based on biometrics. If you use electronic signatures that are not based upon biometrics you...) Electronic signatures based on biometrics. If you use electronic signatures based upon biometrics, they...

  3. 27 CFR 73.11 - What are the required components and controls for acceptable electronic signatures?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... signatures not based on biometrics. If you use electronic signatures that are not based upon biometrics you...) Electronic signatures based on biometrics. If you use electronic signatures based upon biometrics, they...

  4. 27 CFR 73.11 - What are the required components and controls for acceptable electronic signatures?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... signatures not based on biometrics. If you use electronic signatures that are not based upon biometrics you...) Electronic signatures based on biometrics. If you use electronic signatures based upon biometrics, they...

  5. 27 CFR 73.11 - What are the required components and controls for acceptable electronic signatures?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... signatures not based on biometrics. If you use electronic signatures that are not based upon biometrics you...) Electronic signatures based on biometrics. If you use electronic signatures based upon biometrics, they...

  6. Assessing signatures of selection through variation in linkage disequilibrium between taurine and indicine cattle

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Signatures of selection are regions in the genome that have been preferentially maintained because of their functional importance in specific processes. These regions can be detected because of their lower genetic variability and specific regional linkage disequilibrium patterns. The varLD methodol...

  7. Progress in interpreting CO2 lidar signatures to obtain cirrus microphysical and optical properties

    NASA Technical Reports Server (NTRS)

    Eberhard, Wynn L.

    1993-01-01

    One cloud/radiation issue at FIRE 2 that has been addressed by the CO2 lidar team is the zenith-enhanced backscatter (ZEB) signature from oriented crystals. A second topic is narrow-beam optical depth measurements using CO2 lidar. This paper describes the theoretical models we have developed for these phenomena and the data-processing algorithms derived from them.

  8. Failure Modes and Diagnostic Signatures Working Group - Ignition Diagnostics Requirements Update

    SciTech Connect

    Cerjan, C; Haan, S; Hatchett, S; Koch, J

    2007-03-26

    We have performed an initial assessment of the sensitivity of various expected ignition diagnostic signatures to ignition failure modes using one and two-dimensional hydrodynamics simulations and post-processed simulated diagnostic output. As a result of this assessment, we recommend several changes to the current requirements for the ignition diagnostic suite. These recommendations are summarized in Table 1.

  9. Chili peppers: Challenges and advances in transitioning harvesting of New Mexico's signature crop

    Technology Transfer Automated Retrieval System (TEKTRAN)

    New Mexico-type chile (Capsicum annuum L.), often referred to as ‘Anaheim’, is the signature crop of New Mexico. Both the red and green (fully sized, but physiologically immature) crops are celebrated in local cuisine, culture and art, and production and processing of chile is an integral contributo...

  10. Convergent antibody signatures in human dengue.

    PubMed

    Parameswaran, Poornima; Liu, Yi; Roskin, Krishna M; Jackson, Katherine K L; Dixit, Vaishali P; Lee, Ji-Yeun; Artiles, Karen L; Zompi, Simona; Vargas, Maria José; Simen, Birgitte B; Hanczaruk, Bozena; McGowan, Kim R; Tariq, Muhammad A; Pourmand, Nader; Koller, Daphne; Balmaseda, Angel; Boyd, Scott D; Harris, Eva; Fire, Andrew Z

    2013-06-12

    Dengue is the most prevalent mosquito-borne viral disease in humans, and the lack of early prognostics, vaccines, and therapeutics contributes to immense disease burden. To identify patterns that could be used for sequence-based monitoring of the antibody response to dengue, we examined antibody heavy-chain gene rearrangements in longitudinal peripheral blood samples from 60 dengue patients. Comparing signatures between acute dengue, postrecovery, and healthy samples, we found increased expansion of B cell clones in acute dengue patients, with higher overall clonality in secondary infection. Additionally, we observed consistent antibody sequence features in acute dengue in the highly variable major antigen-binding determinant, complementarity-determining region 3 (CDR3), with specific CDR3 sequences highly enriched in acute samples compared to postrecovery, healthy, or non-dengue samples. Dengue thus provides a striking example of a human viral infection where convergent immune signatures can be identified in multiple individuals. Such signatures could facilitate surveillance of immunological memory in communities. PMID:23768493

  11. Active place recognition using image signatures

    NASA Astrophysics Data System (ADS)

    Engelson, Sean P.

    1992-11-01

    For reliable navigation, a mobile robot needs to be able to recognize where it is in the world. We previously described an efficient and effective image-based representation of perceptual information for place recognition. Each place is associated with a set of stored image signatures, each a matrix of numbers derived by evaluating some measurement functions over large blocks of pixels. One difficulty, though, is the large number of inherently ambiguous signatures which bloats the database and makes recognition more difficult. Furthermore, since small differences in orientation can produce very different images, reliable recognition requires many images. These problems can be ameliorated by using active methods to select the best signatures to use for the recognition. Two criteria for good images are distinctiveness (is the scene distinguishable from others?) and stability (how much do small viewpoint motions change image recognizability?). We formulate several heuristic distinctiveness metrics which are good predictors of real image distinctiveness. These functions are then used to direct the motion of the camera to find locally distinctive views for use in recognition. This method also produces some modicum of stability, since it uses a form of local optimization. We present the results of applying this method with a camera mounted on a pan-tilt platform.

  12. On psychoanalytic supervision as signature pedagogy.

    PubMed

    Watkins, C Edward

    2014-04-01

    What is signature pedagogy in psychoanalytic education? This paper examines that question, considering why psychoanalytic supervision best deserves that designation. In focusing on supervision as signature pedagogy, I accentuate its role in building psychoanalytic habits of mind, habits of hand, and habits of heart, and transforming theory and self-knowledge into practical product. Other facets of supervision as signature pedagogy addressed in this paper include its features of engagement, uncertainty, formation, and pervasiveness, as well as levels of surface, deep, and implicit structure. Epistemological, ontological, and axiological in nature, psychoanalytic supervision engages trainees in learning to do, think, and value what psychoanalytic practitioners in the field do, think, and value: It is, most fundamentally, professional preparation for competent, "good work." In this paper, effort is made to shine a light on and celebrate the pivotal role of supervision in "making" or developing budding psychoanalysts and psychoanalytic psychotherapists. Now over a century old, psychoanalytic supervision remains unparalleled in (1) connecting and integrating conceptualization and practice, (2) transforming psychoanalytic theory and self-knowledge into an informed analyzing instrument, and (3) teaching, transmitting, and perpetuating the traditions, practice, and culture of psychoanalytic treatment. PMID:24731044

  13. SIGNATURES OF LONG-LIVED SPIRAL PATTERNS

    SciTech Connect

    Martinez-Garcia, Eric E.; Gonzalez-Lopezlira, Rosa A. E-mail: martinez@astro.unam.mx

    2013-03-10

    Azimuthal age/color gradients across spiral arms are a signature of long-lived spirals. From a sample of 19 normal (or weakly barred) spirals where we have previously found azimuthal age/color gradient candidates, 13 objects were further selected if a two-armed grand-design pattern survived in a surface density stellar mass map. Mass maps were obtained from optical and near-infrared imaging, by comparison with a Monte Carlo library of stellar population synthesis models that allowed us to obtain the mass-to-light ratio in the J band, (M/L){sub J}, as a function of (g - i) versus (i - J) color. The selected spirals were analyzed with Fourier methods in search of other signatures of long-lived modes related to the gradients, such as the gradient divergence toward corotation, and the behavior of the phase angle of the two-armed spiral in different wavebands, as expected from theory. The results show additional signatures of long-lived spirals in at least 50% of the objects.

  14. Spectroscopic characterization of nitroaromatic landmine signature explosives

    NASA Astrophysics Data System (ADS)

    Hernandez-Rivera, Samuel P.; Manrique-Bastidas, Cesar A.; Blanco, Alejandro; Primera, Oliva M.; Pacheco, Leonardo C.; Castillo-Chara, Jairo; Castro, Miguel E.; Mina, Nairmen

    2004-09-01

    TNT and DNT are important explosives used as base charges of landmines and other explosive devices. They are often combined with RDX in specific explosive formulations. Their detection in vapor phase as well as in soil in contact with the explosives is important in landmine detection technology. The spectroscopic signatures of nitroaromatic compounds in neat forms: crystals, droplets, and recrystallized samples were determined by Raman Microspectroscopy (RS), Fourier Transform Infrared Microscopy (FTIR) and Fiber Optics Coupled - Fourier Transform Infrared Spectroscopy (FOC-FTIR) using a grazing angle (GA) probe. TNT exhibits a series of characteristic bands: vibrational signatures, which allow its detection in soil. The spectroscopic signature of neat TNT is dominated by strong bands about 1380 and 2970 cm-1. The intensity and position of these bands were found remarkably different in soil samples spiked with TNT. The 1380 cm-1 band is split into a number of bands in that region. The 2970 cm-1 band is reduced in intensity and new bands are observed about 2880 cm-1. The results are consistent with a different chemical environment of TNT in soil as compared to neat TNT. Interactions were found to be dependent on the physical source of the explosive. In the case of DNT-sand interactions, shifts in vibrational frequencies of the explosives as well as the substrates were found.

  15. Online Signature Verification Using Fourier Descriptors

    NASA Astrophysics Data System (ADS)

    Yanikoglu, Berrin; Kholmatov, Alisher

    2009-12-01

    We present a novel online signature verification system based on the Fast Fourier Transform. The advantage of using the Fourier domain is the ability to compactly represent an online signature using a fixed number of coefficients. The fixed-length representation leads to fast matching algorithms and is essential in certain applications. The challenge on the other hand is to find the right preprocessing steps and matching algorithm for this representation. We report on the effectiveness of the proposed method, along with the effects of individual preprocessing and normalization steps, based on comprehensive tests over two public signature databases. We also propose to use the pen-up duration information in identifying forgeries. The best results obtained on the SUSIG-Visual subcorpus and the MCYT-100 database are 6.2% and 12.1% error rate on skilled forgeries, respectively. The fusion of the proposed system with our state-of-the-art Dynamic Time Warping (DTW) system lowers the error rate of the DTW system by up to about 25%. While the current error rates are higher than state-of-the-art results for these databases, as an approach using global features, the system possesses many advantages. Considering also the suggested improvements, the FFT system shows promise both as a stand-alone system and especially in combination with approaches that are based on local features.

  16. Lung Cancer Gene Signatures and Clinical Perspectives

    PubMed Central

    Kuner, Ruprecht

    2013-01-01

    Microarrays have been used for more than two decades in preclinical research. The tumor transcriptional profiles were analyzed to select cancer-associated genes for in-deep functional characterization, to stratify tumor subgroups according to the histopathology or diverse clinical courses, and to assess biological and cellular functions behind these gene sets. In lung cancer—the main type of cancer causing mortality worldwide—biomarker research focuses on different objectives: the early diagnosis of curable tumor diseases, the stratification of patients with prognostic unfavorable operable tumors to assess the need for further therapy regimens, or the selection of patients for the most efficient therapies at early and late stages. In non-small cell lung cancer, gene and miRNA signatures are valuable to differentiate between the two main subtypes’ squamous and non-squamous tumors, a discrimination which has further implications for therapeutic schemes. Further subclassification within adenocarcinoma and squamous cell carcinoma has been done to correlate histopathological phenotype with disease outcome. Those tumor subgroups were assigned by diverse transcriptional patterns including potential biomarkers and therapy targets for future diagnostic and clinical applications. In lung cancer, none of these signatures have entered clinical routine for testing so far. In this review, the status quo of lung cancer gene signatures in preclinical and clinical research will be presented in the context of future clinical perspectives.

  17. A Blind Quantum Signature Scheme with χ-type Entangled States

    NASA Astrophysics Data System (ADS)

    Yin, Xun-Ru; Ma, Wen-Ping; Liu, Wei-Yan

    2012-02-01

    A blind quantum signature scheme with χ-type entangled states is proposed, which can be applied to E-voting system. In this scheme, the particles in χ-type state sequence are used for quantum key distribution first, and then for quantum signature. Our scheme is characterized by its blindness, impossibility of forgery, impossibility of disavowal. In addition, our scheme can perform an audit program with respect to the validity of the verification process in the light of actual requirements. The security of the scheme is also analyzed.

  18. Detection of ionospheric Alfvén resonator signatures in the equatorial ionosphere

    NASA Astrophysics Data System (ADS)

    Simões, Fernando; Klenzing, Jeffrey; Ivanov, Stoyan; Pfaff, Robert; Freudenreich, Henry; Bilitza, Dieter; Rowland, Douglas; Bromund, Kenneth; Liebrecht, Maria Carmen; Martin, Steven; Schuck, Peter; Uribe, Paulo; Yokoyama, Tatsuhiro

    2012-11-01

    The ionosphere response resulting from minimum solar activity during cycle 23/24 was unusual and offered unique opportunities for investigating space weather in the near-Earth environment. We report ultra low frequency electric field signatures related to the ionospheric Alfvén resonator detected by the Communications/Navigation Outage Forecasting System (C/NOFS) satellite in the equatorial region. These signatures are used to constrain ionospheric empirical models and offer a new approach for monitoring ionosphere dynamics and space weather phenomena, namely aeronomy processes, Alfvén wave propagation, and troposphere-ionosphere-magnetosphere coupling mechanisms.

  19. Identity-Based Verifiably Encrypted Signatures without Random Oracles

    NASA Astrophysics Data System (ADS)

    Zhang, Lei; Wu, Qianhong; Qin, Bo

    Fair exchange protocol plays an important role in electronic commerce in the case of exchanging digital contracts. Verifiably encrypted signatures provide an optimistic solution to these scenarios with an off-line trusted third party. In this paper, we propose an identity-based verifiably encrypted signature scheme. The scheme is non-interactive to generate verifiably encrypted signatures and the resulting encrypted signature consists of only four group elements. Based on the computational Diffie-Hellman assumption, our scheme is proven secure without using random oracles. To the best of our knowledge, this is the first identity-based verifiably encrypted signature scheme provably secure in the standard model.

  20. Classification Aided Analysis of Oscillatory Signatures in Controlled Retrieval

    PubMed Central

    Ketz, Nicholas; O'Reilly, Randal C.; Curran, Tim

    2013-01-01

    Control processes are critical for both facilitating and suppressing memory retrieval, but these processes are not well understood. The current work, inspired by a similar fMRI design (Detre et al., in press), used a modified Think/No-Think(TNT) paradigm to investigate the neural signatures of volition over enhancing and suppressing memory retrieval. Previous studies have shown memory enhancement when well-learned stimulus pairs are restudied in cued recall (“Recall or think of studied pair item”), and degradation when restudied with cued suppression (“Avoid thinking of studied pair item”). We used category-based (faces vs. scenes) multivariate classification of electroencephalography signals to determine if individual target items were successfully retrieved or suppressed. A logistic regression based on classifier output determined that retrieval activation during the cued recall/suppression period was a predictor for subsequent memory. Labeling trials with this internal measure, as opposed to their nominal Think vs. No-Think condition, revealed the classic TNT pattern of enhanced memory for successful cued-retrieval and degraded memory for cued-suppression. This classification process enabled a more selective investigation into the time-frequency signatures of control over retrieval. Comparing controlled retrieval vs. controlled suppression, results showed more prominent Theta oscillations (3 to 8 Hz) in controlled retrieval. Beta oscillations (12 to 30 Hz) were involved in high levels of both controlled retrieval and suppression, suggesting it may have a more general control-related role. These results suggest unique roles for these frequency bands in retrieval processes. PMID:23845425