Science.gov

Sample records for improved cold starts

  1. Alcohol cold starting - A theoretical study

    NASA Technical Reports Server (NTRS)

    Browning, L. H.

    1983-01-01

    Two theoretical computer models have been developed to study cold starting problems with alcohol fuels. The first model, a droplet fall-out and sling-out model, shows that droplets must be smaller than 50 microns to enter the cylinder under cranking conditions without being slung-out in the intake manifold. The second model, which examines the fate of droplets during the compression process, shows that the heat of compression can be used to vaporize small droplets (less than 50 microns) producing flammable mixtures below freezing ambient temperatures. While droplet size has the greater effect on startability, a very high compression ratio can also aid cold starting.

  2. TrustRank: a Cold-Start tolerant recommender system

    NASA Astrophysics Data System (ADS)

    Zou, Haitao; Gong, Zhiguo; Zhang, Nan; Zhao, Wei; Guo, Jingzhi

    2015-02-01

    The explosive growth of the World Wide Web leads to the fast advancing development of e-commerce techniques. Recommender systems, which use personalised information filtering techniques to generate a set of items suitable to a given user, have received considerable attention. User- and item-based algorithms are two popular techniques for the design of recommender systems. These two algorithms are known to have Cold-Start problems, i.e., they are unable to effectively handle Cold-Start users who have an extremely limited number of purchase records. In this paper, we develop TrustRank, a novel recommender system which handles the Cold-Start problem by leveraging the user-trust networks which are commonly available for e-commerce applications. A user-trust network is formed by friendships or trust relationships that users specify among them. While it is straightforward to conjecture that a user-trust network is helpful for improving the accuracy of recommendations, a key challenge for using user-trust network to facilitate Cold-Start users is that these users also tend to have a very limited number of trust relationships. To address this challenge, we propose a pre-processing propagation of the Cold-Start users' trust network. In particular, by applying the personalised PageRank algorithm, we expand the friends of a given user to include others with similar purchase records to his/her original friends. To make this propagation algorithm scalable to a large amount of users, as required by real-world recommender systems, we devise an iterative computation algorithm of the original personalised TrustRank which can incrementally compute trust vectors for Cold-Start users. We conduct extensive experiments to demonstrate the consistently improvement provided by our proposed algorithm over the existing recommender algorithms on the accuracy of recommendations for Cold-Start users.

  3. PEM Fuel Cell Freeze Durability and Cold Start Project

    SciTech Connect

    Patterson, T.; O'Neill, Jonathan

    2008-01-02

    UTC has taken advantage of the unique water management opportunities inherent in micro-porous bipolar-plates to improve the cold-start performance of its polymer electrolyte fuel cells (PEFC). Diagnostic experiments were used to determine the limiting factors in micro-porous plate PEFC freeze performance and the causes of any performance decay. Alternative cell materials were evaluated for their freeze performance. Freeze-thaw cycling was also performed to determine micro-porous plate PEFC survivability. Data from these experiments has formed the basis for continuing development of advanced materials capable of supporting DOE's cold-start and durability objectives.

  4. Modeling Cold Start in a Polymer-Electrolyte Fuel Cell

    NASA Astrophysics Data System (ADS)

    Balliet, Ryan James

    Polymer-electrolyte fuel cells (PEFCs) are electrochemical devices that create electricity by consuming hydrogen and oxygen, forming water and heat as byproducts. PEFCs have been proposed for use in applications that may require start-up in environments with temperatures below 0 degrees C. Doing so requires that the cell heat up, and when its own waste heat is used to do so, the process is referred to here as "cold start.'' However, at low temperatures the cell's product water freezes, and if the temperature does not rise fast enough, the accumulation of ice in the cathode catalyst layer (cCL) can reduce cell performance significantly, extending the time required to heat up. In addition to reducing performance during cold start, under some conditions the accumulation of ice can lead to irreversible structural degradation of the cCL. The objective of this dissertation is to construct and verify a cold-start model for a single PEFC, use it to improve understanding of cold-start behavior, and to demonstrate how this understanding can lead to better start protocols and material properties. The macrohomogeneous model that has been developed to meet the objective is two-dimensional, transient, and nonisothermal. A key differentiating feature is the inclusion of water in all four of the possible phases: ice, liquid, gas, and membrane. In order to predict water content in the ice, liquid, and gas phases that are present in the porous media, the thermodynamics of phase equilibrium are revisited, and a method for relating phase pressures to water content in each of these phases is developed. Verification of the model is performed by comparing model predictions for cell behavior during parametric studies to measured values taken from various sources. In most cases, good agreement is observed between the model and the experiments. Results from the simulations are used to explain the trends that are observed. The verified cold-start model is deployed to determine a cold-start

  5. Cold-start, is it good or bad

    SciTech Connect

    Lanthier, G.

    1993-02-01

    An awful lot has been said on cold-starting a boiler, but from discussions I recently have had I am sure everybody understands what it really means, and from what I can see, that includes some manufacturers too. The reason I wonder is because of the so called horror stories' I hear about cold-start.

  6. Cold starting system for alcohol fueled engine

    SciTech Connect

    Powell, T.M.

    1983-04-26

    To restart an alcohol fueled engine at low temperatures, a quantity of liquid ethanol is supplied to a vaporizing chamber before the engine is stopped. When restarting the engine, some of the alcohol in the vaporizing chamber is delivered to an igniter, and the hot gases resulting from the burning alcohol are conducted past the vaporizing chamber to evaporate the liquid alcohol remaining in the vaporizing chamber. The alcohol vapor thus generated is conducted to the engine induction system to start the engine.

  7. Modeling and cold start in alcohol-fueled engines

    SciTech Connect

    Markel, A.J.; Bailey, B.K.

    1998-05-01

    Neat alcohol fuels offer several benefits over conventional gasoline in automotive applications. However, their low vapor pressure and high heat of vaporization make it difficult to produce a flammable vapor composition from a neat alcohol fuel during a start under cold ambient conditions. Various methods have been introduced to compensate for this deficiency. In this study, the authors applied computer modeling and simulation to evaluate the potential of four cold-start technologies for engines fueled by near-neat alcohol. The four technologies were a rich combustor device, a partial oxidation reactor, a catalytic reformer, and an enhanced ignition system. The authors ranked the competing technologies by their ability to meet two primary criteria for cold starting an engine at {minus}25 deg C and also by several secondary parameters related to commercialization. Their analysis results suggest that of the four technologies evaluated, the enhanced ignition system is the best option for further development.

  8. Cold-start characteristics of polymer electrolyte fuel cells

    SciTech Connect

    Mishler, Jeff; Mukundan, Rangachary; Wang, Yun; Mishler, Jeff; Mukherjee, Partha P

    2010-01-01

    In this paper, we investigate the electrochemical reaction kinetics, species transport, and solid water dynamics in a polymer electrolyte fuel cell (PEFC) during cold start. A simplitied analysis is developed to enable the evaluation of the impact of ice volume fraction on cell performance during coldstart. Supporting neutron imaging data are also provided to reveal the real-time water evolution. Temperature-dependent voltage changes due to the reaction kinetics and ohmic loss are also analyzed based on the ionic conductivity of the membrane at subfreezing temperature. The analysis is valuable for the fundamental study of PEFC cold-start.

  9. Evaluation of resistively heated fuel injection technology to reduce cold start emissions and assist starting/driveaway of a methanol-fueled vehicle

    NASA Astrophysics Data System (ADS)

    Piotrowski, Gregory K.; Schaefer, Ronald M.

    1992-03-01

    The report provides the results from a program to evaluate a set of heated fuel injectors on an M100 fueled vehicle in an attempt to lower cold start emissions of unburned fuel and carbon monoxide and to improve cold start ability and drive ability. This technology was evaluated at several different temperatures.

  10. White smoke emissions under cold starting of diesel engines

    SciTech Connect

    Yassine, M.K.; Tagomori, M.K.; Henein, N.A.; Bryzik, W.

    1996-09-01

    More stringent regulations have been enforced over the past few years on diesel exhaust emissions. White smoke emission, a characteristic of diesel engines during cold starting, needs to be controlled in order to meet these regulations. This study investigates the sources and constituents of white smoke. The effects of fuel properties, design and operating parameters on the formation and emissions of white smoke are discussed. A new technique is developed to measure the real time gaseous hydrocarbons (HC) as well as the solid and liquid particulates. Experiments were conducted on a single cylinder direct injection diesel engine in a cold room. The gaseous HC emissions are measured using a high frequency response flame ionization detector. The liquid and solid particulates are collected on a paper filter placed upstream of the sampling line of the FID and their masses are determined. A comparative study is made between white smoke in its three forms for diesel fuel (DF2) and jet fuel (JP8). The fuel accumulated in the engine during cranking plays a major role in the emissions of white smoke under cold starting conditions.

  11. Promoting cold-start items in recommender systems.

    PubMed

    Liu, Jin-Hu; Zhou, Tao; Zhang, Zi-Ke; Yang, Zimo; Liu, Chuang; Li, Wei-Min

    2014-01-01

    As one of the major challenges, cold-start problem plagues nearly all recommender systems. In particular, new items will be overlooked, impeding the development of new products online. Given limited resources, how to utilize the knowledge of recommender systems and design efficient marketing strategy for new items is extremely important. In this paper, we convert this ticklish issue into a clear mathematical problem based on a bipartite network representation. Under the most widely used algorithm in real e-commerce recommender systems, the so-called item-based collaborative filtering, we show that to simply push new items to active users is not a good strategy. Interestingly, experiments on real recommender systems indicate that to connect new items with some less active users will statistically yield better performance, namely, these new items will have more chance to appear in other users' recommendation lists. Further analysis suggests that the disassortative nature of recommender systems contributes to such observation. In a word, getting in-depth understanding on recommender systems could pave the way for the owners to popularize their cold-start products with low costs. PMID:25479013

  12. Promoting Cold-Start Items in Recommender Systems

    PubMed Central

    Liu, Jin-Hu; Zhou, Tao; Zhang, Zi-Ke; Yang, Zimo; Liu, Chuang; Li, Wei-Min

    2014-01-01

    As one of the major challenges, cold-start problem plagues nearly all recommender systems. In particular, new items will be overlooked, impeding the development of new products online. Given limited resources, how to utilize the knowledge of recommender systems and design efficient marketing strategy for new items is extremely important. In this paper, we convert this ticklish issue into a clear mathematical problem based on a bipartite network representation. Under the most widely used algorithm in real e-commerce recommender systems, the so-called item-based collaborative filtering, we show that to simply push new items to active users is not a good strategy. Interestingly, experiments on real recommender systems indicate that to connect new items with some less active users will statistically yield better performance, namely, these new items will have more chance to appear in other users' recommendation lists. Further analysis suggests that the disassortative nature of recommender systems contributes to such observation. In a word, getting in-depth understanding on recommender systems could pave the way for the owners to popularize their cold-start products with low costs. PMID:25479013

  13. Reducing cold-start emissions by catalytic converter thermal management

    SciTech Connect

    Burch, S D; Potter, T F; Keyser, M A; Brady, M J; Michaels, K F

    1995-01-01

    Vacuum insulation and phase-change thermal storage have been used to enhance the heat retention of a prototype catalytic converter. Storing heat in the converter between trips allows exhaust gases to be converted more quickly, significantly reducing cold-start emissions. Using a small metal hydride, the thermal conductance of the vacuum insulation can be varied continuously between 0.49 and 27 W/m{sup 2}K (R-12 to R-0.2 insulation) to prevent overheating of the catalyst. A prototype was installed in a Dodge Neon with a 2.0-liter engine. Following a standard preconditioning and a 23-hour cold soak, an FTP (Federal Test Procedure) emissions test was performed. Although exhaust temperatures during the preconditioning were not hot enough to melt the phase-change material, the vacuum insulation performed well, resulting in a converter temperature of 146{degrees}C after the 23-hour cold soak at 27{degrees}C. Compared to the same converter at ambient conditions, overall emissions of CO and HC were reduced by 52 % and 29 %, to 0.27 and 0.037 g/mile, respectively. The maximum converter temperature during the FTP cycle was 720{degrees}C. This limited testing was performed with a nearly-fresh palladium-only catalyst, but demonstrates the potential of this vacuum insulation approach for emissions reduction and thermal control. Further testing is ongoing. An initial assessment of several production issues is made, including high-volume fabrication challenges, durability, and cost.

  14. Cold starting an alcohol-fueled engine with ultrasonic fuel atomization

    NASA Astrophysics Data System (ADS)

    Bruetsch, R. I.; Hamady, F. J.

    1993-03-01

    A test program was devised at EPA's National Vehicle and Fuel Emissions Laboratory to evaluate a Tonen ultrasonic fuel atomizer system on a Honda B20 engine using both M85 (85% methanol, 15% hydrocarbons) and M100 (neat methanol) fuels to determine whether cold starting a premixed-charge port injected engine on alcohol fuels at low ambient temperatures can be improved. Modification to the engine's intake manifold was performed at the Japanese Automotive Research Institute (JARI) in cooperation with the New Energy Development Organization (NEDO) to install heated injectors in close proximity to the ultrasonic atomizers. The engine is also equipped with the stock port injector system intact and functional. Successful M100 cold starts were obtained down to 20 F (-7 C).

  15. Pseudo one-dimensional analysis of polymer electrolyte fuel cell cold-start

    SciTech Connect

    Mukherjee, Partha P; Mukundan, Rangachary; Borup, Rodney L; Wang, Yun; Mishlera, Jeff

    2009-01-01

    This paper investigates the electrochemical kinetics, oxygen transport, and solid water formation in polymer electrolyte fuel cell (PEFC) during cold start. Following [Yo Wang, J. Electrochem. Soc., 154 (2007) B1041-B1048], we develop a pseudo one-dimensional analysis, which enables the evaluation of the impact of ice volume fraction and temperature variations on cell performance during cold-start. The oxygen profile, starvation ice volume fraction, and relevant overpotentials are obtained. This study is valuable for studying the characteristics of PEFC cold-start.

  16. Cold-start and chemical characterization of emissions from mobile sources in Mexico.

    PubMed

    Schifter, I; Díaz, L; Rodríguez, R

    2010-10-01

    In this work tailpipe and evaporative emissions from a set of normal and high emitter vehicle models, year 2006-2008 (low mileage) certified when new to meet the Tier 1 emission standard, were characterized for criteria pollutants (carbon monoxide, nitrogen oxides and hydrocarbons), and a suite of unregulated emissions including aliphatic and aromatic aldehydes, monocyclic aromatic compounds, 1,3 butadiene, n-hexane and acrolein. Data were obtained under the three different driving conditions of the United States Federal Test Procedure, FTP-75 cycle. High emissions of both regulated and unregulated pollutants were observed in the cold-start phase of the driving cycle for low mileage Tier 1 normal and high emitters engines. Data were compared with results obtained for a set of MY > 1992-2005 that included vehicles with no catalytic converters, Tier 0 and MY 2000-5 Tier 1 emission standard with high mileage. The calculated average cold-start emissions for normal emitters in grams are 0.93, 8.21 and 1.06 for NMHC CO, and NOx, respectively for Tier 1 low mileage vehicles. The reductions in emissions for Tier 1 normal emitters are 76%, 56% and 56% for NMHC, CO and NOx, respectively, but 58%, 30% and 25% for the high emitters. Differences in emission can be ascribed to the mileage accumulation more than technological improvements. Cold-start emissions account in the USA roughly 10% of emissions from gasoline-powered vehicles. In Mexico the fractions are likely to be higher because one must account also for the contribution of Tier 0 and the running exhausts emissions of vehicles with no catalytic converters. PMID:21046954

  17. Cold start characteristics of ethanol as an automobile fuel

    DOEpatents

    Greiner, Leonard

    1982-01-01

    An alcohol fuel burner and decomposer in which one stream of fuel is preheated by passing it through an electrically heated conduit to vaporize the fuel, the fuel vapor is mixed with air, the air-fuel mixture is ignited and combusted, and the combustion gases are passed in heat exchange relationship with a conduit carrying a stream of fuel to decompose the fuel forming a fuel stream containing hydrogen gas for starting internal combustion engines, the mass flow of the combustion gas being increased as it flows in heat exchange relationship with the fuel carrying conduit, is disclosed.

  18. Comparison of exhaust emissions resulting from cold- and hot-start motorcycle driving modes.

    PubMed

    Yao, Yung-Chen; Tsai, Jiun-Horng; Ye, Hui-Fen; Chiang, Hung-Lung

    2009-11-01

    This study investigated the emissions of criteria air pollutants (carbon monoxide [CO], hydrocarbons [HCs], and oxides of nitrogen [NOx]) from motorcycle exhaust at cold- and hot-start driving cycles on a chassis dynamometer. Seven four-stroke carburetors and two fuel-injection motorcycles were tested. As expected, the emission factors (g/km) of CO and HCs increased during cold-start driving. The ratio of emission factors (g/km) for cold- and hot-start driving cycles ranged from 1.1-1.5 (for CO) to 1.2-2.8 (for HCs). However, the difference of NOx emissions between the cold- and hot-start cycles was not pronounced. Further, the cold-/hot-start ratios of CO and HCs from 50-cm3 motorcycles were higher than those of 100- and 125-cm3 motorcycles; however, the carbon dioxide (CO2) emission was the lowest for the four-stroke motorcycles. High engine temperature and poor combustion efficiency of smaller cylinder-capacity motorcycles may contribute a significant amount of exhaust emission. Additionally, the fuel-base emission factor (g/L-fuel) ratios were low compared with the distance-base emission factor (g/km) in cold- and hot-start driving. This indicates that the effect of catalyst efficiency was greater than the effect of fuel combustion in the tested motorcycles. A comparison of emission ratios of motorcycles and passenger cars shows that the warm-up may be more important for cars, especially under low-temperature conditions. However, the motorcycle contributes a large proportion of CO and HC emissions in many Asian counties. The difference between cold- and hot-start emissions may affect inventory PMID:19947115

  19. Improvements in Cold-Plate Fabrication

    NASA Technical Reports Server (NTRS)

    Zaffetti, Mark A.; Taddey, Edmund P.; Laurin, Michael B.; Chabebe, Natalia

    2012-01-01

    Five improvements are reported in cold-plate fabrication. This cold plate is part of a thermal control system designed to serve on space missions. The first improvement is the merging of the end sheets of the cold plate with the face sheets of the structural honeycomb panel. The cold plate, which can be a brazed assembly, uses the honeycomb face sheet as its end sheet. Thus, when the honeycomb panel is fabricated, the face sheet that is used is already part of the cold plate. In addition to reducing weight, costs, and steps, the main benefit of this invention is that it creates a more structurally sound assembly. The second improvement involves incorporation of the header into the closure bar to pass the fluid to a lower layer. Conventional designs have used a separate header, which increases the geometry of the system. The improvement reduces the geometry, thus allowing the cold plate to fit into smaller area. The third improvement eliminates the need of hose, tube, or manifold to supply the cooling fluid externally. The external arrangement can be easily damaged and is vulnerable to leakage. The new arrangement incorporates an internal fluid transfer tube. This allows the fluid to pass from one cold plate to the other without any exposed external features. The fourth improvement eliminates separate fabrication of cold plate(s) and structural members followed by a process of attaching them to each other. Here, the structural member is made of material that can be brazed just as that of the cold plate. Now the structural member and the cold plate can be brazed at the same time, creating a monolithic unit, and thus a more structurally sound assembly. Finally, the fifth improvement is the elimination of an additional welding step that can damage the braze joints. A tube section, which is usually welded on after the braze process, is replaced with a more structurally sound configuration that can be brazed at the same time as the rest of the cold plate.

  20. Statistic analysis of operational influences on the cold start behaviour of PEM fuel cells

    NASA Astrophysics Data System (ADS)

    Oszcipok, M.; Riemann, D.; Kronenwett, U.; Kreideweis, M.; Zedda, M.

    For portable fuel cell systems a multitude of applications have been presented over the past few years. Most of these applications were developed for indoor use, and not optimised for outdoor conditions. The key problem concerning this case is the cold start ability of the polymer electrolyte membrane fuel cell (PEMFC). This topic was first investigated by the automotive industry, which has the same requirements for alternative traction systems as for conventional combustion engines. The technical challenge is the fact that produced water freezes to ice after shut-down of the PEMFC and during start-up when the temperature is below 0 °C. To investigate the basic cold start behaviour isothermal, potentiostatic single cell experiments were performed and the results are presented. The cold start behaviour is evaluated using the calculated cumulated charge transfer through the membrane which directly corresponds with the amount of produced water in the PEMFC. The charge transfer curves were mathematically fitted to obtain only three parameters describing the cold start-up with the cumulated charge transfer density and the results are analysed using the statistical software Cornerstone 4.0. The results of the statistic regression analyses are used to establish a statistic-based prediction model of the cold start behaviour which describes the behaviour of the current density during the experiment. The regression shows that the initial start current mainly depends on the membrane humidity and the operation voltage. After the membrane humidity has reached its maximum, the current density drops down to zero. The current decay also depends on the constant gas flows of the reactant gases. Ionic conductivity of the membrane and charge transfer resistance were investigated by a series of ac impedance spectra during potentiostatic operation of the single cell at freezing temperatures. Cyclic voltammetry and polarisation curves between cold start experiments show degradation

  1. Cold-sensitive mutants of Taq DNA polymerase provide a hot start for PCR

    PubMed Central

    Kermekchiev, Milko B.; Tzekov, Anatoly; Barnes, Wayne M.

    2003-01-01

    Although the thermophilic bacterium Thermus aquaticus grows optimally at 70°C and cannot grow at moderate temperatures, its DNA polymerase I has significant activity at 20–37°C. This activity is a bane to some PCRs, since it catalyzes non-specific priming. We report mutations of Klentaq (an N-terminal deletion variant) DNA polymerase that have markedly reduced activity at 37°C yet retain apparently normal activity at 68°C and resistance at 95°C. The first four of these mutations are clustered on the outside surface of the enzyme, nowhere near the active site, but at the hinge point of a domain that has been proposed to move at each cycle of nucleotide incorporation. We show that the novel cold-sensitive mutants can provide a hot start for PCR and exhibit slightly improved fidelity. PMID:14576300

  2. Parametric study on the fuel film breakup of a cold start PFI engine

    NASA Astrophysics Data System (ADS)

    Wang, Y.-P.; Wilkinson, G. B.; Drallmeier, J. A.

    In order to provide more insight on improving the cold start fuel atomization for reducing unburned hydrocarbon emissions, the liquid fuel film breakup phenomenon in the intake valve/port region was investigated in depth for port-fuel-injected engines. Experiments were conducted using high-speed high-resolution imaging techniques to visualize the liquid film atomization and airflow patterns in an axisymmetric steady flow apparatus. The impact of valve/port seat geometry, surface roughness, and fuel properties on airflow separation and fuel film breakup were determined through a parametric study. CFD simulations were also performed with FLUENT to help understand the airflow behavior inside the intake port and valve gap region and its potential impact on fuel film atomization.

  3. Low temperature operation and influence parameters on the cold start ability of portable PEMFCs

    NASA Astrophysics Data System (ADS)

    Oszcipok, M.; Zedda, M.; Riemann, D.; Geckeler, D.

    The start up behaviour of PEM fuel cells below 0 °C is one of the most challenging tasks to be solved before commercialisation. The automotive industry started to develop solutions to reduce the start up time of fuel cell systems in the middle of the nineties. The strategies varied from catalytic combustion of hydrogen on the electrode catalyst to fuel starvation or external stack heating via cooling loops to increase the stack temperature. Beside the automotive sector the cold start ability is as well important for portable PEMFC applications for outdoor use. But here the cold start issue is even more complicated, as the fuel cell system should be operated as passive as possible. Below 0 °C freezing of water inside the PEMFC could form ice layers in the electrode and in the gas diffusion layer. Therefore the cell reaction is limited or even inhibited. Product water during the start up builds additional barriers and leads to a strong decay of the output power at isothermal operating conditions. In order to find out which operational and hardware parameters affect this decay, potentiostatic experiments on single cells were performed at isothermal conditions. These experiments comprise investigations of the influence of membrane thickness and different GDL types as well as the effect of gas flow rates and humidification levels of the membrane. As pre stage to physical based models, empirical based prediction models are used to gain a better understanding of the main influence parameters during cold start. The results are analysed using the statistical software Cornerstone 4.0. The experience of single cell investigations are compared to start up behaviour of portable fuel cell stacks which are operated in a climate chamber at different ambient temperatures below 0 °C. Additional flow sharing problems in the fuel cell stack could be seen during cold start up experiments.

  4. Middle Start Snapshots: Improving Middle-Grades Schools

    ERIC Educational Resources Information Center

    Academy for Educational Development, 2005

    2005-01-01

    This publication describes the school-improvement process in three schools participating in Middle Start, a comprehensive school-improvement program for schools with middle grades. Middle Start services, grounded in the Middle Start Principles and Practices, are tailored to a school's specific needs. The schools profiled are Bendle Middle School…

  5. Investigation and demonstration of a rich combustor cold-start device for alcohol-fueled engines

    SciTech Connect

    Hodgson, J W; Irick, D K

    1998-04-01

    The authors have completed a study in which they investigated the use of a rich combustor to aid in cold starting spark-ignition engines fueled with either neat ethanol or neat methanol. The rich combustor burns the alcohol fuel outside the engine under fuel-rich conditions to produce a combustible product stream that is fed to the engine for cold starting. The rich combustor approach significantly extends the cold starting capability of alcohol-fueled engines. A design tool was developed that simulates the operation of the combustor and couples it to an engine/vehicle model. This tool allows the user to determine the fuel requirements of the rich combustor as the vehicle executes a given driving mission. The design tool was used to design and fabricate a rich combustor for use on a 2.8 L automotive engine. The system was tested using a unique cold room that allows the engine to be coupled to an electric dynamometer. The engine was fitted with an aftermarket engine control system that permitted the fuel flow to the rich combustor to be programmed as a function of engine speed and intake manifold pressure. Testing indicated that reliable cold starts were achieved on both neat methanol and neat ethanol at temperatures as low as {minus}20 C. Although starts were experienced at temperatures as low as {minus}30 C, these were erratic. They believe that an important factor at the very low temperatures is the balance between the high mechanical friction of the engine and the low energy density of the combustible mixture fed to the engine from the rich combustor.

  6. Ice-Crystallization Kinetics during Fuel-Cell Cold-Start

    NASA Astrophysics Data System (ADS)

    Dursch, Thomas James, Jr.

    Proton-exchange-membrane fuel cells (PEMFCs) show promise in automotive applications because of their high efficiency, high power density, and potentially low emissions. To be successful in automobiles, PEMFCs must permit rapid startup with minimal energy from subfreezing temperatures, known as cold-start. In a PEMFC, reduction of oxygen to water occurs in the cathode catalyst layer (CL). Under subfreezing conditions, water generated during startup solidifies and hinders access of gaseous oxygen to the catalytic sites in the cathode CL, severely inhibiting cell performance and potentially causing cell failure. Achieving cold-start is difficult in practice, due to potential flooding, sluggish reaction kinetics, durability loss, and rapid ice crystallization. Currently, however, few studies focus on the fundamentals of ice crystallization during cold-start. Elucidation of the mechanisms and kinetics of ice formation within PEMFC porous media is, therefore, critical to successful cell startup and high performance at low temperatures. First, an experimental method is presented for obtaining isothermal ice-crystallization kinetics in water-saturated gas-diffusion layers (GDLs). Ice formation is initially studied in the GDL because this layer retains a significant amount of product water during cold-start. Isothermal ice-crystallization and ice-nucleation rates are obtained in commercial Toray GDLs as functions of subcooling using differential scanning calorimetry (DSC). A nonlinear ice-crystallization rate expression is developed using Johnson-Mehl-Avrami-Kolmogorov (JMAK) theory, in which the heat-transfer-limited growth rate is determined from the moving-boundary Stefan problem. Predicted ice-crystallization rates are in excellent agreement with experiment. A validated rate expression is thus available for predicting ice-crystallization kinetics in GDLs. Ice-crystallization kinetics is also considered under experimental settings similar to real PEMFC operating

  7. Cold-Start Emissions Control in Hybrid Vehicles Equipped with a Passive Hydrocarbon and NOx Adsorber

    SciTech Connect

    Gao, Zhiming; Kim, Miyoung; Choi, Jae-Soon; Daw, C Stuart; Parks, II, James E; Smith, David E

    2012-01-01

    We presents a study of the potential for using low-cost sorbent materials (i.e. Ag-Beta-zeolite and Fe-Mn-Zr transition metal oxides) to temporally trap hydrocarbons (HCs) and nitrogen oxides (NOx) emissions during cold-start periods in HEVs and PHEVs over transient driving cycles. The adsorption behavior of the candidate sorbent materials was characterized in our laboratory flow reactor experiments. The parameters were then used to develop a one-dimensional, transient device model which has been implemented in the Powertrain Systems Analysis Toolkit (PSAT) to simulate a passive HC and NOx absorber device. The results show that such an absorber can substantially reduce HC and NOx emissions by storing them when the 3-way catalyst is too cool to function and re-releasing them when the exhaust temperature rises. These improved emission controls do not involve any penalty in fuel consumption or require any change in engine operation. The cost of these sorbent materials is also much less than conventional 3-way catalysts.

  8. A personal sampler for aircraft engine cold start particles: laboratory development and testing.

    PubMed

    Armendariz, Alfredo; Leith, David

    2003-01-01

    Industrial hygienists in the U.S. Air Force are concerned about exposure of their personnel to jet fuel. One potential source of exposure for flightline ground crews is the plume emitted during the start of aircraft engines in extremely cold weather. The purpose of this study was to investigate a personal sampler, a small tube-and-wire electrostatic precipitator (ESP), for assessing exposure to aircraft engine cold start particles. Tests were performed in the laboratory to characterize the sampler's collection efficiency and to determine the magnitude of adsorption and evaporation artifacts. A low-temperature chamber was developed for the artifact experiments so tests could be performed at temperatures similar to actual field conditions. The ESP collected particles from 0.5 to 20 micro m diameter with greater than 98% efficiency at particle concentrations up to 100 mg/m(3). Adsorption artifacts were less than 5 micro g/m(3) when sampling a high concentration vapor stream. Evaporation artifacts were significantly lower for the ESP than for PVC membrane filters across a range of sampling times and incoming vapor concentrations. These tests indicate that the ESP provides more accurate exposure assessment results than traditional filter-based particle samplers when sampling cold start particles produced by an aircraft engine. PMID:14674798

  9. Regulated and nonregulated diesel and gasoline cold start emissions at different temperatures

    NASA Astrophysics Data System (ADS)

    Weilenmann, Martin; Soltic, Patrik; Saxer, Christian; Forss, Anna-Maria; Heeb, Norbert

    The emissions of modern cars are usually reduced in warm engine conditions by catalysts. Consequently emissions are significantly higher during the cold start, i.e. the warm-up phase of the car. The duration of this period and the emissions produced during it depend on the ambient temperature as well as on the initial temperature of the car's systems. The cold start emissions of Euro-3 gasoline cars, Euro-2 diesel cars and old pre-Euro-1 gasoline cars were investigated at cold ambient temperatures. Since the goal was to get real-world emissions, the measurements were done with cars belonging to private owners taken straight from the road with no maintenance. The chassis dynamometer tests were carried out at +23, -7 and -20 °C. The test cycle employed is a representative urban ride from a real-world driving behaviour study. Besides the regulated pollutants, methane, benzene and toluene were also measured online by chemical ionisation mass spectrometry.

  10. Ice-Crystallization Kinetics during Fuel-Cell Cold-Start

    NASA Astrophysics Data System (ADS)

    Dursch, Thomas James, Jr.

    Proton-exchange-membrane fuel cells (PEMFCs) show promise in automotive applications because of their high efficiency, high power density, and potentially low emissions. To be successful in automobiles, PEMFCs must permit rapid startup with minimal energy from subfreezing temperatures, known as cold-start. In a PEMFC, reduction of oxygen to water occurs in the cathode catalyst layer (CL). Under subfreezing conditions, water generated during startup solidifies and hinders access of gaseous oxygen to the catalytic sites in the cathode CL, severely inhibiting cell performance and potentially causing cell failure. Achieving cold-start is difficult in practice, due to potential flooding, sluggish reaction kinetics, durability loss, and rapid ice crystallization. Currently, however, few studies focus on the fundamentals of ice crystallization during cold-start. Elucidation of the mechanisms and kinetics of ice formation within PEMFC porous media is, therefore, critical to successful cell startup and high performance at low temperatures. First, an experimental method is presented for obtaining isothermal ice-crystallization kinetics in water-saturated gas-diffusion layers (GDLs). Ice formation is initially studied in the GDL because this layer retains a significant amount of product water during cold-start. Isothermal ice-crystallization and ice-nucleation rates are obtained in commercial Toray GDLs as functions of subcooling using differential scanning calorimetry (DSC). A nonlinear ice-crystallization rate expression is developed using Johnson-Mehl-Avrami-Kolmogorov (JMAK) theory, in which the heat-transfer-limited growth rate is determined from the moving-boundary Stefan problem. Predicted ice-crystallization rates are in excellent agreement with experiment. A validated rate expression is thus available for predicting ice-crystallization kinetics in GDLs. Ice-crystallization kinetics is also considered under experimental settings similar to real PEMFC operating

  11. Assessment and correlation of customer and rater response to cold-start and warmup driveability

    SciTech Connect

    Not Available

    1993-08-01

    A program was conducted from January 14 through March 8, 1991, at Southwest Research Institute (SwRI) in San Antonio, Texas, to establish a relationship between demerits observed in CRC Cold-Start and Warmup Driveability assessments to customer satisfaction levels, and to determine which of several performance deficiencies associated with low volatility gasolines are most troublesome to customers during normal vehicle warmup. Customers used their vehicles in daily service, and a subset of the test fleet was evaluated by trained raters using the established CRC test procedure. There were 7,206 driveability performance assessments by customers which were correlated with 661 trained-rater cold-start driveability evaluations. One hundred sixty-seven SwRI employees participated in the program. Hesitation was the most widely observed problem and was the primary cause of dissatisfaction. The gasoline-ethanol and hydrocarbon-only fuel sets had distinctly different malfunction patterns. Hesitation was strongly associated with gasoline ethanol blends, while surge and stumble were strongly associated with hydrocarbon-only fuels. The current total weighted demerit (TWD) system was found to correlate poorly with customer satisfaction; however, customer observations of problems correlated no better with customer satisfaction. If TWD is to be an indicator of customer perception of driveability performance there should be uniform weighting of rater-observed malfunctions, and start-time should be assigned a greater weighting and a shorter grace period.

  12. Cold Start of a Radiator Equipped with Titanium-Water Heat Pipes

    NASA Technical Reports Server (NTRS)

    Jaworske, Donald A.; Sanzi, James L.; Siamidis, John

    2008-01-01

    Radiator panels utilizing titanium-water heat pipes are being considered for lunar applications. A traditional sandwich structure is envisioned where heat pipes are embedded between two high thermal conductivity face sheets. The heat pipe evaporators are to be thermally connected to the heat source through one or more manifolds containing coolant. Initial radiator operation on the lunar surface would likely follow a cold soak where the water in the heat pipes is purposely frozen. To achieve heat pipe operation, it will be necessary to thaw the heat pipes. One option is to allow the sunlight impinging on the surface at sunrise to achieve this goal. Testing was conducted in a thermal vacuum chamber to simulate the lunar sunrise and additional modeling was conducted to identify steady-state and transient response. It was found that sunlight impinging on the radiator surface at sunrise was insufficient to solely achieve the goal of thawing the water in the heat pipes. However, starting from a frozen condition was accomplished successfully by applying power to the evaporators. Start up in this fashion was demonstrated without evaporator dryout. Concern is raised over thawing thermosyphons, vertical heat pipes operating in a gravity field, with no wick in the condenser section. This paper presents the results of the simulated cold start study and identifies future work to support radiator panels equipped with titanium-water heat pipes.

  13. On-board generation of a highly volatile starting fuel to reduce automobile cold-start emissions.

    PubMed

    Ashford, Marcus D; Matthews, Ronald D

    2006-09-15

    The on-board distillation system (OBDS) was developed to extract, from gasoline, a high-volatility fuel for exclusive use during the starting and warm-up periods. The use of OBDS distillate fuel results in much improved mixture preparation, allowing combinations of air/fuel ratio and ignition timing that are not possible with gasoline, even with a fully warm engine. The volatility of the distillate is a function of the parent fuel volatility; however, the variability in distillate quality can be diminished via manipulation of the OBDS operating conditions. Thus, it is possible to develop aggressive starting calibrations that are relatively immune to variations in pump gasoline volatility. The key benefits provided bythe OBDS fuel relative to standard gasoline were found to be (1) improved mixture preparation allowing a 70% reduction of cranking fuel requirements, elimination of air-fuel mixture enrichment during the warm-up period, and significant extension of warm-up ignition timing retard; (2) a 57% decrease in catalyst light-off time, (3) emissions reductions over the FTP drive cycle of 81% for regulated hydrocarbons (NMOG); (4) emissions index (NMOG) approaching that of SULEV/PZEV vehicles; and (5) an apparent 1% increase in fuel economy over the FTP drive cycle. PMID:17007139

  14. Dielectric heating catalytic converter system for reducing cold-start emissions

    SciTech Connect

    Takatsu, Katsumi; Kurogi, Fumiyasu; Matsue, Akihiro; Kasaya, Masashi

    1996-09-01

    To reduce the harmful pollutants in cold start emissions, this study has been considering microwave dielectric technique for rapid catalyst heating. A dielectric material, having a relatively large loss factor at 2.45GHz was selected. This was coated to the exhaust catalyst allowing microwave energy to be deposited efficiently. The developed system has been tested successfully using a single-mode cavity in conjunction with a model gas. Moreover, a concept for practical in-vehicle system using the microwave heated catalyst has been proposed.

  15. Cold start fuel consumption of a diesel and a petrol car

    SciTech Connect

    Pearce, T.C.; Waters, M.H.L.

    1980-01-01

    Measurements have been made of the fuel consumption of a petrol and a diesel car when starting from cold. The cars were the 1.1 liter petrol VW Golf and the 1.5 liter diesel version, which have the same passenger accommodation and nearly identical road performance. It was found that the diesel car used less fuel in the warm-up period than the petrol, both when being driven at constant speed on a test track and with the engine idling and the car stationary. (Copyright (c) Crown Copyright 1980.)

  16. Evidence of cold bubble-like structure in START density limit plasmas

    SciTech Connect

    Ribeiro, C.; Jenkins, I.; Martin, R.; Sykes, A.; Walsh, M. J.

    2008-09-15

    Cold bubble (CB) structures were observed in START density limit studies for the first time in a low aspect ratio tokamak. They seem related to minor and major disruption processes, clearly identified here as a trigger to those events. Enormous discrepancies on the CB velocities in several devices are reported. This shows that the physical mechanisms related to the time scales for its propagation should be revised. Several models related to CB formation and its role in the disruptive process or just in a plasma with the presence of sawteeth qualitatively predict a great part of the observations.

  17. Cold start dynamics and temperature sliding observer design of an automotive SOFC APU

    NASA Astrophysics Data System (ADS)

    Lin, Po-Hsu; Hong, Che-Wun

    This paper presents a dynamic model for studying the cold start dynamics and observer design of an auxiliary power unit (APU) for automotive applications. The APU is embedded with a solid oxide fuel cell (SOFC) stack which is a quiet and pollutant-free electric generator; however, it suffers from slow start problem from ambient conditions. The SOFC APU system equips with an after-burner to accelerate the start-up transient in this research. The combustion chamber burns the residual fuel (and air) left from the SOFC to raise the exhaust temperature to preheat the SOFC stack through an energy recovery unit. Since thermal effect is the dominant factor that influences the SOFC transient and steady performance, a nonlinear real-time sliding observer for stack temperature was implemented into the system dynamics to monitor the temperature variation for future controller design. The simulation results show that a 100 W APU system in this research takes about 2 min (in theory) for start-up without considering the thermal limitation of the cell fracture.

  18. CuH-ZSM-5 as hydrocarbon trap under cold start conditions.

    PubMed

    Navlani-García, M; Puértolas, B; Lozano-Castelló, D; Cazorla-Amorós, D; Navarro, M V; García, T

    2013-06-01

    Cold start tests are carried out to evaluate the performance of copper-exchanged zeolites as hydrocarbon traps under simulated gasoline car exhaust gases, paying special attention to the role of copper in the performance of these zeolites. It is concluded that the partial substitution of the protons in the parent H-ZSM-5 zeolite is highly beneficial for hydrocarbon trapping due to the formation of selective adsorption sites with specific affinity for the different exhaust components. However, it is also observed that uncontrolled exchanging process conditions could lead to the presence of CuO nanoparticles in the zeolite surface, which seem to block the pore structure of the zeolite, decreasing the hydrocarbon trap efficiency. Among all the zeolites studied, the results point out that a CuH-ZSM-5 with a partial substitution of extra-framework protons by copper cations and without any detectable surface CuO nanoparticles is the zeolite that showed the best performance under simulated cold start conditions due to both the high stability and the hydrocarbon retaining capacity of this sample during the consecutive cycles. PMID:23634959

  19. Improving on-time surgical starts in an operating room

    PubMed Central

    Wright, James G.; Roche, Ann; Khoury, Antoine E.

    2010-01-01

    Background Operating rooms are expensive to run, and hospitals strive to be efficient. The purpose of this study was to evaluate an initiative to improve starting on time in the operating room in an academic pediatric hospital. Methods We used an 8-step approach to transforming an organization. A multidisciplinary team defined on-time starts, identified reasons for delays and instituted changes, including improving the same-day admission process, instituting a huddle of operating room staff each morning and providing feedback about on-time starts to staff. Results The most common reasons for delay were surgeon and anesthesiologist unavailability and lack of preparedness of patients. The percentage of operations that began on time, defined as the patient being in the room, increased from about 6% to 60% over a 9-month period. Conclusion A targeted, multifaceted and multidisciplinary approach can increase the percentage of operations that begin on time in a pediatric hospital. PMID:20507788

  20. An item-oriented recommendation algorithm on cold-start problem

    NASA Astrophysics Data System (ADS)

    Qiu, Tian; Chen, Guang; Zhang, Zi-Ke; Zhou, Tao

    2011-09-01

    Based on a hybrid algorithm incorporating the heat conduction and probability spreading processes (Proc. Natl. Acad. Sci. U.S.A., 107 (2010) 4511), in this letter, we propose an improved method by introducing an item-oriented function, focusing on solving the dilemma of the recommendation accuracy between the cold and popular items. Differently from previous works, the present algorithm does not require any additional information (e.g., tags). Further experimental results obtained in three real datasets, RYM, Netflix and MovieLens, show that, compared with the original hybrid method, the proposed algorithm significantly enhances the recommendation accuracy of the cold items, while it keeps the recommendation accuracy of the overall and the popular items. This work might shed some light on both understanding and designing effective methods for long-tailed online applications of recommender systems.

  1. Improved Starting Materials for Back-Illuminated Imagers

    NASA Technical Reports Server (NTRS)

    Pain, Bedabrata

    2009-01-01

    An improved type of starting materials for the fabrication of silicon-based imaging integrated circuits that include back-illuminated photodetectors has been conceived, and a process for making these starting materials is undergoing development. These materials are intended to enable reductions in dark currents and increases in quantum efficiencies, relative to those of comparable imagers made from prior silicon-on-insulator (SOI) starting materials. Some background information is prerequisite to a meaningful description of the improved starting materials and process. A prior SOI starting material, depicted in the upper part the figure, includes: a) A device layer on the front side, typically between 2 and 20 m thick, made of p-doped silicon (that is, silicon lightly doped with an electron acceptor, which is typically boron); b) A buried oxide (BOX) layer (that is, a buried layer of oxidized silicon) between 0.2 and 0.5 m thick; and c) A silicon handle layer (also known as a handle wafer) on the back side, between about 600 and 650 m thick. After fabrication of the imager circuitry in and on the device layer, the handle wafer is etched away, the BOX layer acting as an etch stop. In subsequent operation of the imager, light enters from the back, through the BOX layer. The advantages of back illumination over front illumination have been discussed in prior NASA Tech Briefs articles.

  2. A Comparison of Hypnotic Induction, Task Motivation, and a "Cold Start" Control Group on Hypnotizability.

    PubMed

    Krystek, Stephen; Kumar, V K

    2016-10-01

    Groups of participants (N = 164) were randomly assigned to three conditions: Group 1 received a trance induction, Group 2 received task-motivational instructions, and Group 3-"cold start" control-was simply told, "We will begin the hypnosis procedure now." All participants received the Creative Imagination Scale suggestions and then completed the Creative Imagination Scale and Inventory Scale of Hypnotic Depth. The three conditions did not differ significantly either on the Creative Imagination Scale or in reported hypnotic depth. These results are consistent with prior studies which show that trance induction and task-motivational yield similar results, but they are inconsistent inasmuch as the trance induction and task-motivational groups did not differ from the control group. These results, however, are predictable from socio-cognitive perspectives that the context of hypnosis itself can elicit hypnotic behaviors. PMID:27586049

  3. Flames and liquid fuel in an SI engine cylinder during cold start

    SciTech Connect

    Campbell, S.; Clasen, E.; Chang, C.; Rhee, K.

    1996-05-01

    The flame propagations in the very first firing and subsequent cycles in an SI engine during cold start were studied to gain a better understanding of reaction fronts associated with liquid fuel (regular unleaded) in the cylinder. This work was performed using the Rutgers high-speed spectral infrared digital imaging system on a single-cylinder engine with optical access. The engine was mounted with a production engine head mated with a conventional pon fuel injection (PFI) system. In the study, four images in respective spectral bands were simultaneously obtained at successive instants of time, which was done for eight sequential cycles. This multiple-band successive-imaging was repeated in intervals of about two minutes over a period of more than twenty-five minutes after the engine start. During this experiment, the temperature changes at the intake port, the water jacket and the exhaust gas were monitored. In addition, pressure-time data was obtained from individual cycles in order to gain some insight into the overall in-cylinder reactions. The first firing cycle exhibited almost invariably weak flame propagation, which was followed by very intense flame fronts in the next cycle. Note that the flame propagation in the first cycle seems to only indicate consumption of the filel vapor available in the cycle. The flames in the third cycle were also intense in some cases, but mostly weaker than those in the second. Upon formation of the flame front in the beginning of combustion, some exceedingly strong local reactions started to grow, but no earlier than l5CA after TDC.

  4. Improving on-time start for iMRI neurosurgeries

    PubMed Central

    Ghadiali, Natascha Fherzinah Rustom; Koh, Darren; Chia, Kuok Wei; Quek, Shin Yi

    2013-01-01

    Background: In the Singapore General Hospital, intraoperative MRI (iMRI) neurosurgery is a multi-disciplinary process that involves staff from multiple departments. However, a baseline analysis showed that only 10.5% of iMRI neurosurgeries start on time, resulting in unnecessary waste of resources. The project aimed to improve the percentage of on-time start iMRI neurosurgeries to 100% within nine months. Materials and Methods: Clinical Practice Improvement methodology was used. The project involves four phases: Diagnostic, in which a baseline analysis is conducted; Intervention, in which problem areas are identified; Implementation, in which potential solutions are implemented; and sustaining, in which strategies to sustain gains are discussed. Results: The percentage of on-time start cases gradually increased to 100% in eight months, and was sustained above 85% in the following five months. Conclusion: This project serves as a successful demonstration of how quality improvement can be effected in a complex, multidisciplinary workflow, which is the norm for many hospital procedures. PMID:23741256

  5. Investigation of Diesel combustion using multiple injection strategies for idling after cold start of passenger-car engines

    SciTech Connect

    Payri, F.; Broatch, A.; Salavert, J.M.; Martin, J.

    2010-10-15

    A comprehensive investigation was carried out in order to better understand the combustion behaviour in a low compression ratio DI Diesel engine when multiple injection strategies are applied just after the engine cold starts in low temperature conditions (idling). More specifically, the aim of this study was twofold: on one hand, to understand the effect of the multiple injection strategies on the indicated mean effective pressure; on the other hand, to contribute to the understanding of combustion stability characterized by the coefficient of variation of indicated mean effective pressure. The first objective was fulfilled by analyzing the rate of heat release obtained by in-cylinder pressure diagnosis. The results showed that the timing of the pilot injection closest to the main injection was the most influential parameter based on the behaviour of the rate of heat release (regardless of the multiple injection strategy applied). For the second objective, the combustion stability was found to be correlated with the combustion centroid angle. The results showed a trend between them and the existence of a range of centroid angles where the combustion stability is strong enough. In addition, it was also evident that convenient split injection allows shifting the centroid to such a zone and improves combustion stability after start. (author)

  6. Michigan Middle Start Studies of Middle Start School Improvement, Lake Middle School: A Case Study.

    ERIC Educational Resources Information Center

    Gopalan, Pritha

    This case study documented the collaboration of Lake Middle School (pseudonym for a school in Michigan) with Middle Start, a middle-grades reform model and its progress and struggles implementing the model. Middle Start was coordinated by the Michigan Middle Start Partnership, and alliance that provided technical assistance, professional…

  7. Cold-start minidiesel engine development. Final report, July 1991-March 1992

    SciTech Connect

    Collins, C.

    1993-09-01

    Military mission performance in a chemically contaminated environment necessitates the wearing of chemically impermeable protective garments. Soldiers encapsulated in these protective garments will succumb to heat stress in a hot environment. Consequently, a microclimate cooling system is being developed. In the design, a vapor compression cycle chills water which is then circulated over the body to absorb heat via a cooling garment. The engine, the prime mover in the system, is a major component. Commercially available engines of approximately 0.5 hp at 4000 rpm, the required size, include model aircraft engines and small outdoor power equipment (string trimmer) engines. However, these engines do not run on JP-8 or diesel fuel, a requirement for military use. This report details design, evaluation, and results of three engines. These include: the potential of a high compression, carbureted, glow plug engine operating on diesel fuel; the potential of a high compression, spark assist, fuel injected engine operating on diesel fuel; and a true high compression, fuel injected engine operating on diesel fuel. Diesel engines, Microclimate cooling system, Diesel fuels, Vapor compression, Cold start, Engines.

  8. Improving the cold chain for vaccines.

    PubMed

    Lloyd, J S

    1977-01-01

    The cold chain may be defined as a system for transporting and storing vaccines at very low temperataures, particularly in tropical countries. In Ghana, efforts are being made, with the assistance of the World Health Organization (WHO) to develop and test a new cold chain technology. Emphasis is on local production in order to meet the needs of the countrywide immunization program, and, if possible, of similar programs in other West African nations. Focus in this discussion is on the losses resulting from mishandling of vaccines during storage and in transit through various stages in the cold chain as well as the problems, requirements, and proposed solutions. In most countries with immunization programs, breakdowns in refrigeration during the transport and storage of vaccines in remote rural areas or at the regional and national central stores have led to great losses of vaccine. The losses are often caused by inappropriate management and technology. The most promising recent development in the area of storage is an enzyme-based time/temperature indicator contained in a paper tab which is attached to the vaccine packet. In order to reduce to a minimum the handling of vaccines at the national central store it is proposed that the ministry of health submit details of regional requirements in their requisition to the manufacturer. Then the manufacturer can make presealed packages which are dispatched by air to the national central store and from there to the regions, while they are still sealed. Insulated boxes for this purpose have been tested in Sweden and been shown to maintain deep-freezing temperatures for 5 days. Road communications to the regional centers are good in Ghana and the 5-day cold boxes give adequate safety margins. The plan for the immunization program in Ghana is to employ a combination of teams from both fixed and mobile centers. 3 contacts, 3 months apart, will be made by the fixed teams; mobile teams will make 2 contacts, 2 months apart. Mobile

  9. Cold start extra emissions as a function of engine stop time: Evolution over the last 10 years

    NASA Astrophysics Data System (ADS)

    Favez, Jean-Yves; Weilenmann, Martin; Stilli, Jan

    Cars with catalysts show a significant increase in exhaust emissions at engine start. These extra emissions are expressed as the difference, over a particular driving cycle, between emissions generated when the vehicle is started and when the engine or the catalyst are stably warm. Experimental data, suitable for the assessment of cold start emissions, are usually available for completely cooled engines. Most results originate from tests at ambient temperature of 20-30 °C and with an engine stop time of at least 12 h. On the other hand, data including shorter stop times are very rare. The present work investigates the influence of exhaust emissions with shorter stop times, i.e. 0.5, 1, 2 and 4 h. The main goal consists in the comparison of emissions exhausted by recent car models (Euro-4) against emissions assessed in the framework of a similar campaign 10 years ago (FAV1/Euro-1 vehicles). A short survey of the current extra emission estimation methods is presented in this paper. It is shown that some methods are not suited for providing correct estimations in all cases. We discuss the fact that different estimation methods can show either similar or completely different results depending on the evolution behaviour of the hot emissions. Due to new technologies, e.g. the catalyst and improved engine control algorithms, emissions have been considerably reduced over the last 10 years. In this study it is determined how the relative extra emissions, i.e. extra emissions relative to the extra emissions for the standard stop time of 12 h, expressed as a function of stop time have changed. We may claim with caution that for medium stop times of 0.5-4 h the average relative extra emissions of Euro-4 vehicles are well below the average of the relative extra emissions of Euro-1 vehicles.

  10. Optimizing the performance of catalytic traps for hydrocarbon abatement during the cold-start of a gasoline engine.

    PubMed

    Puértolas, B; Navlani-García, M; García, T; Navarro, M V; Lozano-Castelló, D; Cazorla-Amorós, D

    2014-08-30

    A key target to reduce current hydrocarbon emissions from vehicular exhaust is to improve their abatement under cold-start conditions. Herein, we demonstrate the potential of factorial analysis to design a highly efficient catalytic trap. The impact of the synthesis conditions on the preparation of copper-loaded ZSM-5 is clearly revealed by XRD, N2 sorption, FTIR, NH3-TPD, SEM and TEM. A high concentration of copper nitrate precursor in the synthesis improves the removal of hydrocarbons, providing both strong adsorption sites for hydrocarbon retention at low temperature and copper oxide nanoparticles for full hydrocarbon catalytic combustion at high temperature. The use of copper acetate precursor leads to a more homogeneous dispersion of copper oxide nanoparticles also providing enough catalytic sites for the total oxidation of hydrocarbons released from the adsorption sites, although lower copper loadings are achieved. Thus, synthesis conditions leading to high copper loadings jointly with highly dispersed copper oxide nanoparticles would result in an exceptional catalytic trap able to reach superior hydrocarbon abatement under highly demanding operational conditions. PMID:25108828

  11. Effect of a Smart Start Playground Improvement Grant on Child Care Playground Hazards. Smart Start Evaluation Report.

    ERIC Educational Resources Information Center

    Kotch, Jonathan; Guthrie, Christine

    Smart Start (North Carolina) playground improvement grants were awarded to cover playground safety assessment, planning and evaluation, quality enhancements (such as fencing, surfacing, and new equipment), and safety programs. Visual inspections were conducted of the safety of child care home and center playgrounds after Smart Start-sponsored…

  12. Improving cold tolerance in elderly rats by aminophylline.

    PubMed

    Lee, T F; Wang, L C

    1985-05-27

    During severe cold exposure, old rats (23-26 months) were less capable in maintaining normal body temperature as compared to young rats (6-9 months) due to lower rate of heat production (HP). Single injection of optimal doses of aminophylline (AMPY; 10 and 18.7 mg/kg, i.p.), a phosphodiesterase inhibitor which enhances the intracellular cyclic AMP concentration, significantly increased the rate of HP in old rats to levels beyond the control values observed in young rats. Consequently, cold tolerance of the old rats was significantly improved. This AMPY-improved cold tolerance is apparently not due to increased non-shivering thermogenesis (NST) since AMPY failed to enhance norepinephrine-stimulated NST in the old rats. It is likely that AMPY increased substrate mobilization and/or conversion, thereby circumventing the limiting role of substrate availability for shivering thermogenesis. Thus, the age-dependent decrease in cold tolerance may be due to a reduced capacity for substrate mobilization when challenged by cold. PMID:3999913

  13. The use Na, Li, K cations for modification of ZSM-5 zewolite to control hydrocarbon cold-start emission

    SciTech Connect

    Golubeva V.; Rohatgi U.; Korableva, A.; Anischenko, O.; Kustov, L.; Nissenbaum, V; Viola, M.B.

    2012-08-29

    This paper addresses the problem of controlling hydrocarbon emissions from cold-start of engines by investigating the adsorbents which could adsorb the hydrocarbons at cold temperatures and hold them to 250-300 ?. The materials, that has been studied, are based on the modification of ZSM-5 (SiO{sub 2}/Al{sub 2}O{sub 3} = 35) zeolite with Li, K, Na cations. It has been shown that the introduction of Li, Na and K in an amount that is equivalent to the content of Al in zeolite results in occurrence of toluene temperature desorption peaks at high-temperatures. The toluene temperature desorption curves for 5%Li-ZSM-5 and 2.3%Na-ZSM-5 zeolites are identical and have peak toluene desorption rate between 200 to 400 ?. Upon analysis of toluene adsorption isotherms for 2.3%Na-ZSM-5 and 5%Li-ZSM-5, it was concluded that the toluene diffusion inside of the modified zeolites channels is extremely slow and the sorption capacity of 2.3%Na-ZSM-5 is higher than with 5%Li-ZSM-5. The 2.3%Na-ZSM-5 didn't change toluene temperature programmed desorption (TPD) rate of curve after the treatment in environment with 10% ?{sub 2}? at 750-800 ? for about 28 h. The 2.3%Na-ZSM-5 zeolite is very promising as adsorbent to control the cold-start hydrocarbon emissions.

  14. Getting started with the model for improvement: psychology and leadership in quality improvement.

    PubMed

    Pratap, J Nick; Varughese, Anna M; Adler, Elena; Kurth, C Dean

    2013-02-01

    Although the case for quality in hospitals is compelling, doctors are often uncertain how to achieve it. This article forms the third and final part of a series providing practical guidance on getting started with a first quality improvement project. Introduction. PMID:23411980

  15. Improvement of cold resistance and performance of broilers by acute cold exposure during late embryogenesis.

    PubMed

    Shinder, D; Ruzal, M; Giloh, M; Druyan, S; Piestun, Y; Yahav, S

    2011-03-01

    The aim of this study was to fine-tune previous acute cold exposure treatments of broiler embryos during late embryogenesis to improve lifelong cold resistance and performance. Six hundred Cobb hatching eggs were incubated under standard conditions and then exposed to 3 treatments: control; cold treatment in which embryos were exposed to 15°C for 30 min on d 18 and 19 of incubation (30 × 2); and cold treatment similar to 30 × 2 but with 60-min exposures (60 × 2). Egg shell temperature (T(egg)) and heart rate (HR) were monitored pre- and posttreatment. Upon hatching, hatchability, body weight, and body temperature were recorded. From 14 to 35 d of age, three quarters of the chickens in each treatment were raised under ascites-inducing conditions (AIC) and the remaining birds were raised under standard brooding conditions (SBC). The T(egg) and HR decreased significantly in response to increased exposure time on d 18 of incubation. On d 19 of incubation, before the second cold exposure, the 30 × 2 group showed greater T(egg) and HR than the controls, and during the second exposure they maintained these parameters better than the 60 × 2 embryos. No treatment effect on hatchability was observed. At 35 d of age ascites incidence among 30 × 2 chickens under AIC was significantly less than that among the controls (P < 0.01), and body weight of these chickens under either SBC or AIC was significantly higher than that of the controls. Under SBC relative breast muscle weight was significantly higher in 60 × 2 chickens, whereas the relative heart weight was higher in both cold-treated groups than in the controls. It can be concluded that repeated short acute cold exposures during late embryogenesis significantly reduced ascites incidence and improved growth rate under either SBC or AIC. These results may be related to a prenatal epigenetic adaptation of the thermoregulatory and cardiovascular systems to low ambient temperature. PMID:21325235

  16. Sampling and analysis of aircraft engine cold start particles and demonstration of an electrostatic personal particle sampler.

    PubMed

    Armendariz, Alfredo; Leith, David; Boundy, Maryanne; Goodman, Randall; Smith, Les; Carlton, Gary

    2003-01-01

    Aircraft engines emit an aerosol plume during startup in extremely cold weather that can drift into areas occupied by flightline ground crews. This study tested a personal sampler used to assess exposure to particles in the plume under challenging field conditions. Area and personal samples were taken at two U.S. Air Force (USAF) flightlines during the winter months. Small tube-and-wire electrostatic precipitators (ESPs) were mounted on a stationary stand positioned behind the engines to sample the exhaust. Other ESPs were worn by ground crews to sample breathing zone concentrations. In addition, an aerodynamic particle sizer 3320 (APS) was used to determine the size distribution of the particles. Samples collected with the ESP were solvent extracted and analyzed with gas chromatography-mass spectrometry. Results indicated that the plume consisted of up to 75 mg/m(3) of unburned jet fuel particles. The APS showed that nearly the entire particle mass was respirable, because the plumes had mass median diameters less than 2 micro m. These tests demonstrated that the ESP could be used at cold USAF flightlines to perform exposure assessments to the cold start particles. PMID:14674797

  17. Improving Efficiency of Aluminium Sacrificial Anode Using Cold Work Process

    NASA Astrophysics Data System (ADS)

    Asmara, Y. P.; Siregar, J. P.; Tezara, C.; Ann, Chang Tai

    2016-02-01

    Aluminium is one of the preferred materials to be used as sacrificial anode for carbon steel protection. The efficiency of these can be low due to the formation of oxide layer which passivate the anodes. Currently, to improve its efficiency, there are efforts using a new technique called surface modifications. The objective of this research is to study corrosion mechanism of aluminium sacrificial anode which has been processed by cold work. The cold works are applied by reducing the thickness of aluminium sacrificial anodes at 20% and 40% of thickness reduction. The cathodic protection experiments were performed by immersion of aluminium connected to carbon steel cylinder in 3% NaCl solutions. Visual inspections using SEM had been conducted during the experiments and corrosion rate data were taken in every week for 8 weeks of immersion time. Corrosion rate data were measured using weight loss and linear polarization technique (LPR). From the results, it is observed that cold worked aluminium sacrificial anode have a better corrosion performance. It shows higher corrosion rate and lower corrosion potential. The anodes also provided a long functional for sacrificial anode before it stop working. From SEM investigation, it is shown that cold works have changed the microstructure of anodes which is suspected in increasing corrosion rate and cause de-passivate of the surface anodes.

  18. Initial duct growth determined from cold-start plasma-line data recorded at Arecibo

    NASA Astrophysics Data System (ADS)

    Muldrew, D. B.

    1992-01-01

    The initial development of the HF-enhanced plasma line in a cold ionosphere is investigated. The plasma line is first observed after 3 ms very close to the HF-reflection height and not at the height expected from weak-turbulence theory in a uniformly varying ionosphere. Natural field-aligned ducts with a diameter of a few meters or more can trap Langmuir waves (L waves) generated by the parametric decay instability and propagating nearly parallel to the magnetic field B. The ponderomotive force of the trapped L waves near the highest HF interference maximum causes electrons to be expelled parallel to B and ions to be expelled perpendicular to B. The ion gyroradius is comparable to the smallest duct diameter than can trap L waves. Since it only takes a few milliseconds for the ions to move at their thermal velocity across the duct, the duct can grow in a few milliseconds to a level where L waves capable of backscattering the Arecibo radar can be trapped. Duct growth is eventually limited by Landau damping and/or escape of the ducted L waves.

  19. Advanced hydrogen/methanol utilization technology demonstration. Phase II: Hydrogen cold start of a methanol vehicle

    SciTech Connect

    1995-05-01

    This is the Phase 11 Final Report on NREL Subcontract No. XR-2-11175-1 {open_quotes}Advanced Hydrogen/Methane Utilization Demonstration{close_quotes} between the National Renewable Energy Laboratory (NREL), Alternative Fuels Utilization Program, Golden, Colorado and Hydrogen Consultants, Inc. (HCI), Littleton, Colorado. Mr. Chris Colucci was NREL`s Technical Monitor. Colorado State University`s (CSU) Engines and Energy Conversion Laboratory was HCI`s subcontractor. Some of the vehicle test work was carried out at the National Center for Vehicle Emissions Control and Safety (NCVECS) at CSU. The collaboration of the Colorado School of Mines is also gratefully acknowledged. Hydrogen is unique among alternative fuels in its ability to burn over a wide range of mixtures in air with no carbon-related combustion products. Hydrogen also has the ability to burn on a catalyst, starting from room temperature. Hydrogen can be made from a variety of renewable energy resources and is expected to become a widely used energy carrier in the sustainable energy system of the future. One way to make a start toward widespread use of hydrogen in the energy system is to use it sparingly with other alternative fuels. The Phase I work showed that strong affects could be achieved with dilute concentrations of hydrogen in methane (11). Reductions in emissions greater than the proportion of hydrogen in the fuel provide a form of leverage to stimulate the early introduction of hydrogen. Per energy unit or per dollar of hydrogen, a greater benefit is derived than simply displacing fossil-fueled vehicles with pure hydrogen vehicles.

  20. To Improve Schools, Stop Guessing and Start Using Research

    ERIC Educational Resources Information Center

    Simmons, John

    2011-01-01

    The data are clear: Unless the nation can find a better way to accelerate improvement in the quality of education and implement it in the next 10 years, this nation will lose its competitive edge against other nations and another generation of children will be lost. Eighty percent of Illinois high school graduates are not capable of doing the…

  1. Remote temperature measurements of a cold start-up on a low pressure steam turbine using phosphor thermography

    SciTech Connect

    Allison, S.W.; Beshears, D.L.; Cates, M.R.; Cunningham, G.T.; Puri, A.; Schuster, L.

    1995-12-31

    The feasibility of using a noncontact, optical method for temperature measurement based on thermographic phosphors was explored during the cold start-up of a low pressure turbine rotor at the TVA Cumberland Steam Plant. A simple optical system delivered low power laser light to a segment of the balance rim and balance weight holes which were coated with phosphor. From analysis of the laser induced fluorescence, temperatures ranging from 37C (99 F) to 121 C (250 F) were determined. There was no discernible condensation of steam on the viewing port optics. This transient temperature history at the exit end of the LP rotor may help to determine the root cause of a recent blade failure experienced in the L-0 blade row of a unit at this plant during an overspeed test.

  2. Improved trapping and transport of cold atoms for magnetic microscopy

    NASA Astrophysics Data System (ADS)

    Gadge, Amruta; James, T.; Li, X.; Lu, Bo; Garridogonzalez, N.; Finke, A.; Mellor, C.; Fromhold, M.; Koller, C.; Orucevic, F.; Kruger, Peter

    2016-05-01

    Using cold atoms, a very sensitive and high resolution magnetic and electric field sensor can be realised. Ultra-close trapping of atoms would improve the resolution of cold-atom based surface probes. The limitation on the trapping distance arises from strongly distance-dependent effects such as Casimir force, Johnson noise etc. We are constructing an experimental system to trap atoms at surface separations of less than a micron. We will demonstrate the possibility of using special surfaces such as silicon nitride membranes and graphene for sub-micron trapping. We have designed a 10-layer printed circuit board, which can magnetically trap the cold atom cloud and transport it precisely to a desired location. This gives us the ability to study multiple samples within the same vacuum environment. In order to achieve higher atom number in the initial trapping stages, we use a dual-color MOT technique for Rb-87 atoms. Using this technique we achieve a significant increase in atom number and decrease in temperature. In this talk, I will present the results of the dual color MOT. I will also report on results related to magnetic transport and sub-micron trapping of atoms.

  3. Tradeoffs between global warming and day length on the start of the carbon uptake period in seasonally cold ecosystems.

    PubMed

    Wohlfahrt, Georg; Cremonese, Edoardo; Hammerle, Albin; Hörtnagl, Lukas; Galvagno, Marta; Gianelle, Damiano; Marcolla, Barbara; di Cella, Umberto Morra

    2013-12-16

    It is well established that warming leads to longer growing seasons in seasonally cold ecosystems. Whether this goes along with an increase in the net ecosystem carbon dioxide (CO2) uptake is much more controversial. We studied the effects of warming on the start of the carbon uptake period (CUP) of three mountain grasslands situated along an elevational gradient in the Alps. To this end we used a simple empirical model of the net ecosystem CO2 exchange, calibrated and forced with multi-year empirical data from each site. We show that reductions in the quantity and duration of daylight associated with earlier snowmelts were responsible for diminishing returns, in terms of carbon gain, from longer growing seasons caused by reductions in daytime photosynthetic uptake and increases in nighttime losses of CO2. This effect was less pronounced at high, compared to low, elevations, where the start of the CUP occurred closer to the summer solstice when changes in day length and incident radiation are minimal. PMID:24587563

  4. Third National Even Start Evaluation: Program Impacts and Implications for Improvement.

    ERIC Educational Resources Information Center

    St. Pierre, Robert; Ricciuti, Anne; Tao, Fumiyo; Creps, Cindy; Swartz, Janet; Lee, Wang; Parsad, Amanda; Rimdzius, Tracy

    The Even Start Literacy Program, established in 1989, aims to simultaneously improve the literacy of children and their parents through (1) early childhood education; (2) parenting education; (3) adult education; and (4) parent-child joint literacy activities. The report details findings from the third national Even Start evaluation. The…

  5. Methane, benzene and alkyl benzene cold start emission data of gasoline-driven passenger cars representing the vehicle technology of the last two decades

    NASA Astrophysics Data System (ADS)

    Heeb, Norbert V.; Forss, Anna-Maria; Saxer, Christian J.; Wilhelm, Patrick

    The US urban driving cycle (FTP-75) is widely used to estimate both the emissions under hot engine conditions as well as those associated with the cold start. Applying fast analysis techniques such as chemical ionization mass spectrometry (CI-MS) the warm-up behavior of individual vehicles can be monitored at a time resolution of 1 s. CI-MS has been used to investigate the emissions of methane, benzene and the alkyl benzene class of compounds. The amount of the emissions at cold start influence was deduced from the time-resolved emission data of four gasoline-driven vehicle classes representing the vehicle technology of the last two decades. Overall, the emissions of five EURO-0, 20 EURO-1, 18 EURO-2 and so far of six EURO-3 passenger cars were recorded. The test vehicles were selected from the currently operating Swiss car fleet based on the car sales statistics. The average methane, benzene and alkyl benzene cold start emissions are reported using both, the traditional bag method as well as the regression model. At room temperature a clear reduction of 94%, 81% and 85% was found for the methane, benzene and alkyl benzene cold start emissions from EURO-0 to EURO-3 technology, respectively.

  6. Cold Acclimation Improves Regrowth of Cryopreserved Apple Shoot Tips

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Cryopreservation is important for preserving the genetic resources of apple germplasm in Kazakhstan, the center of origin for apples. In this study of five apple genotypes [Malus domestica Borkh. and Malus sieversii (Ledeb.) M. Roem] we determined cold hardiness and the effect of cold acclimation o...

  7. Intra-arrest Hypothermia: Both Cold Liquid Ventilation with Perfluorocarbons and Cold Intravenous Saline Rapidly Achieve Hypothermia, but Only Cold Liquid Ventilation Improves Resumption of Spontaneous Circulation

    PubMed Central

    Riter, Henry G.; Brooks, Leonard A.; Pretorius, Andrew M.; Ackermann, Laynez W.; Kerber, Richard E.

    2009-01-01

    Background Rapid intra-arrest induction of hypothermia using total liquid ventilation (TLV) with cold perfluorocarbons improves resuscitation outcome from ventricular fibrillation (VF). Cold saline intravenous infusion during cardiopulmonary resuscitation (CPR) is a simpler method of inducing hypothermia. We compared these 2 methods of rapid hypothermia induction for cardiac resuscitation. Methods Three groups of swine were studied: cold preoxygenated TLV (TLV, n=8), cold intravenous saline infusion (S, n=8), and control (C, n=8). VF was electrically induced. Beginning at 8 minutes of VF, TLV and S animals received 3 minutes of cold TLV or rapid cold saline infusion. After 11 minutes of VF, all groups received standard air ventilation and closed chest massage. Defibrillation was attempted after 3 minutes of CPR (14 minutes of VF). The end point was resumption of spontaneous circulation (ROSC). Results Pulmonary arterial (PA) temperature decreased after 1 minute of CPR from 37.2°C to 32.2°C in S and from 37.1°C to 34.8°C in TLV (S or TLV vs. C p<0.0001). Coronary perfusion pressure (CPP) was higher in TLV than S animals during the initial 3 minutes of CPR. Arterial pO2 was higher in the preoxygenated TLV animals. ROSC was achieved in 7 of 8 TLV, 2 of 8 S, and 1 of 8 C (TLV vs. C, p=0.03). Conclusions Moderate hypothermia was achieved rapidly during VF and CPR using both cold saline infusion and cold TLV, but ROSC was higher than control only in cold TLV animals, probably due to better CPP and pO2. The method by which hypothermia is achieved influences ROSC. PMID:19249149

  8. Recommendations to Improve Employee Thermal Comfort When Working in 40°F Refrigerated Cold Rooms.

    PubMed

    Ceballos, Diana; Mead, Kenneth; Ramsey, Jessica

    2015-01-01

    Cold rooms are commonly used for food storage and preparation, and are usually kept around 40°F following food safety guidelines. Some food preparation employees may spend 8 or more hours inside cold rooms. These employees may not be aware of the risks associated with mildly cold temperatures, dampness, and limited ventilation. We performed an evaluation of cold rooms at an airline catering facility because of concerns with exposure to cold temperatures. We spoke with and observed employees in two cold rooms, reviewed daily temperature logs, evaluated employee's physical activity, work/rest schedule, and protective clothing. We measured temperature, percent relative humidity, and air velocities at different work stations inside the cold rooms. We concluded that thermal comfort concerns perceived by cold room employees may have been the result of air drafts at their workstations, insufficient use of personal protective equipment due to dexterity concerns, work practices, and lack of knowledge about good health and safety practices in cold rooms. These moderately cold work conditions with low air velocities are not well covered in current occupational health and safety guidelines, and wind chill calculations do not apply. We provide practical recommendations to improve thermal comfort of cold room employees. Engineering control recommendations include the redesigning of air deflectors and installing of suspended baffles. Administrative controls include the changing out of wet clothing, providing hand warmers outside of cold rooms, and educating employees on cold stress. We also recommended providing more options on personal protective equipment. However, there is a need for guidelines and educational materials tailored to employees in moderately cold environments to improve thermal comfort and minimize health and safety problems. PMID:25961447

  9. Recommendations to Improve Employee Thermal Comfort When Working in 40°F Refrigerated Cold Rooms

    PubMed Central

    Ceballos, Diana; Mead, Kenneth; Ramsey, Jessica

    2015-01-01

    Cold rooms are commonly used for food storage and preparation, and are usually kept around 40°F following food safety guidelines. Some food preparation employees may spend 8 or more hours inside cold rooms. These employees may not be aware of the risks associated with mildly cold temperatures, dampness, and limited ventilation. We performed an evaluation of cold rooms at an airline catering facility because of concerns with exposure to cold temperatures. We spoke with and observed employees in two cold rooms, reviewed daily temperature logs, evaluated employee’s physical activity, work/rest schedule, and protective clothing. We measured temperature, percent relative humidity, and air velocities at different work stations inside the cold rooms. We concluded that thermal comfort concerns perceived by cold room employees may have been the result of air drafts at their workstations, insufficient use of personal protective equipment due to dexterity concerns, work practices, and lack of knowledge about good health and safety practices in cold rooms. These moderately cold work conditions with low air velocities are not well covered in current occupational health and safety guidelines, and wind chill calculations do not apply. We provide practical recommendations to improve thermal comfort of cold room employees. Engineering control recommendations include the redesigning of air deflectors and installing of suspended baffles. Administrative controls include the changing out of wet clothing, providing hand warmers outside of cold rooms, and educating employees on cold stress. We also recommended providing more options on personal protective equipment. However, there is a need for guidelines and educational materials tailored to employees in moderately cold environments to improve thermal comfort and minimize health and safety problems. PMID:25961447

  10. The cold start emissions of light-duty-vehicle fleets: a simplified physics-based model for the estimation of CO₂ and pollutants.

    PubMed

    Weilenmann, Martin F; Soltic, Patrik; Hausberger, Stefan

    2013-02-01

    The emissions from hot driving conditions, in which the exhaust-after-treatment systems are working properly, continue to decrease, which is why the emissions of cold starts have gained in importance. Traffic emission models are used to estimate and predict vehicle fleet emissions and the air quality of countries, regions, cities, etc. In addition to the statistical input of fleet activities, these models are mostly based on the use of separate emission sub-models for hot driving and cold start driving. In reality, the cold start models are almost entirely empirical and of limited accuracy. In this work, a model is developed that is based on physical reasoning, i.e., it is based on energy balances. Because many details, such as the thermal conductivities and the engine control decisions, are unknown, the model must be able to address different simplifications. The model can be parameterized with as few as two tests per vehicle. It is applied to several car samples (six to eight vehicles each) of different technical generations and shows reliable prediction for any combination of the driving pattern (including gradient), the ambient temperature, the stop time before the ride and the duration of the ride (if shorter than the warm-up phase). PMID:23268143

  11. The Effectiveness Of The Manchester Even Start Program In Improving Literacy Outcomes for Preschool Latino Students

    ERIC Educational Resources Information Center

    Ryan, Andrew M.

    2005-01-01

    Although widely implemented, the effectiveness of the Even Start program and other programs involving home-visiting and bilingual education in improving preschool literacy outcomes, particularly among Latino students, is uncertain. This study used a non-equivalent groups design to compare preschool literacy outcomes (measured by the PALS-PreK…

  12. Stop Managing, Start Coaching! How Performance Coaching Can Enhance Commitment and Improve Productivity.

    ERIC Educational Resources Information Center

    Gilley, Jerry W.; Boughton, Nathaniel W.

    This book, which is intended for managers responsible for training and managing employees, outlines an approach to employee management and training that is based on the premise that, if managers are to enhance employees' commitment to the organization and improve productivity, they must first stop managing their employees and start coaching them.…

  13. Improving the cold flow properties of biodiesel with synthetic branched diester additives

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A technical disadvantage of biodiesel relative to petroleum diesel fuel is inferior cold flow properties. One of many methodologies to address this deficiency is employment of cold flow improver (CFI) additives. Generally composed of low-molecular weight copolymers, CFIs originally developed for pet...

  14. Cold climate mapping using satellite high resolution thermal imagery. [weather forecasting improvement

    NASA Technical Reports Server (NTRS)

    Bartholic, J. F.; Sutherland, R. A.

    1977-01-01

    In an attempt to improve cold climate mapping and freeze forecasting techniques, thermal imagery from the NOAA-2 and -3 satellites and the Synchronous Meteorological Satellite (SMS) were obtained and analyzed. Enhanced image transparencies showed detailed temperature patterns over the peninsula of Florida. The analysis was superior to hand-drawn isotherms drawn from the 300 to 500 thermograph stations presently in use. Satellite data on several cold nights with similar synoptic conditions showed that similar cold patterns existed. Thus, cold climate mapping is possible.

  15. Plyometric Long Jump Training With Progressive Loading Improves Kinetic and Kinematic Swimming Start Parameters.

    PubMed

    Rebutini, Vanessa Z; Pereira, Gleber; Bohrer, Roberta C D; Ugrinowitsch, Carlos; Rodacki, André L F

    2016-09-01

    Rebutini, VZ, Pereira, G, Bohrer, RCD, Ugrinowitsch, C, and Rodacki, ALF. Plyometric long jump training with progressive loading improves kinetic and kinematic swimming start parameters. J Strength Cond Res 30(9): 2392-2398, 2016-This study was aimed to determine the effects of a plyometric long jump training program on torque around the lower limb joints and kinetic and kinematics parameters during the swimming jump start. Ten swimmers performed 3 identical assessment sessions, measuring hip and knee muscle extensors during maximal voluntary isometric contraction and kinetic and kinematics parameters during the swimming jump start, at 3 instants: INI (2 weeks before the training program, control period), PRE (2 weeks after INI measurements), and POST (24-48 hours after 9 weeks of training). There were no significant changes from INI to PRE measurements. However, the peak torque and rate of torque development increased significantly from PRE to POST measurements for both hip (47 and 108%) and knee (24 and 41%) joints. There were significant improvements to the horizontal force (7%), impulse (9%), and angle of resultant force (19%). In addition, there were significant improvements to the center of mass displacement (5%), horizontal takeoff velocity (16%), horizontal velocity at water entrance (22%), and peak angle velocity for the knee (15%) and hip joints (16%). Therefore, the plyometric long jump training protocol was effective to enhance torque around the lower limb joints and to control the resultant vector direction, to increase the swimming jump start performance. These findings suggest that coaches should use long jump training instead of vertical jump training to improve swimming start performance. PMID:24531431

  16. A Fast-Start Pacing Strategy Speeds Pulmonary Oxygen Uptake Kinetics and Improves Supramaximal Running Performance

    PubMed Central

    Turnes, Tiago; Salvador, Amadeo Félix; Lisbôa, Felipe Domingos; de Aguiar, Rafael Alves; Cruz, Rogério Santos de Oliveira; Caputo, Fabrizio

    2014-01-01

    The focus of the present study was to investigate the effects of a fast-start pacing strategy on running performance and pulmonary oxygen uptake () kinetics at the upper boundary of the severe-intensity domain. Eleven active male participants (28±10 years, 70±5 kg, 176±6 cm, 57±4 mL/kg/min) visited the laboratory for a series of tests that were performed until exhaustion: 1) an incremental test; 2) three laboratory test sessions performed at 95, 100 and 110% of the maximal aerobic speed; 3) two to four constant speed tests for the determination of the highest constant speed (HS) that still allowed achieving maximal oxygen uptake; and 4) an exercise based on the HS using a higher initial speed followed by a subsequent decrease. To predict equalized performance values for the constant pace, the relationship between time and distance/speed through log-log modelling was used. When a fast-start was utilized, subjects were able to cover a greater distance in a performance of similar duration in comparison with a constant-pace performance (constant pace: 670 m±22%; fast-start: 683 m±22%; P = 0.029); subjects also demonstrated a higher exercise tolerance at a similar average speed when compared with constant-pace performance (constant pace: 114 s±30%; fast-start: 125 s±26%; P = 0.037). Moreover, the mean response time was reduced after a fast start (constant pace: 22.2 s±28%; fast-start: 19.3 s±29%; P = 0.025). In conclusion, middle-distance running performances with a duration of 2–3 min are improved and response time is faster when a fast-start is adopted. PMID:25360744

  17. Strapping rowers to their sliding seat improves performance during the start of single-scull rowing.

    PubMed

    van Soest, A J Knoek; de Koning, H; Hofmijster, M J

    2016-09-01

    In this study, the effect of strapping rowers to their sliding seat on performance during 75 m on-water starting trials was investigated. Well-trained rowers performed 75 m maximum-effort starts using an instrumented single scull equipped with a redesigned sliding seat system, both under normal conditions and while strapped to the sliding seat. Strapping rowers to their sliding seat resulted in a 0.45 s lead after 75 m, corresponding to an increase in average boat velocity of about 2.5%. Corresponding effect sizes were large. No significant changes were observed in general stroke cycle characteristics. No indications of additional boat heaving and pitching under strapped conditions were found. The increase in boat velocity is estimated to correspond to an increase in average mechanical power output during the start of on-water rowing between 5% and 10%, which is substantial but smaller than the 12% increase found in a previous study on ergometer starting. We conclude that, after a very short period of adaptation to the strapped condition, single-scull starting performance is substantially improved when the rower is strapped to the sliding seat. PMID:26758804

  18. Effect of Starting Microstructure on the Grain Refinement in Cold-Rolled Low-Carbon Steel During Annealing at Two Different Heating Rates

    NASA Astrophysics Data System (ADS)

    Karmakar, Anish; Mandal, Madhumanti; Mandal, Abhisek; Basiruddin Sk, Md.; Mukherjee, Subrata; Chakrabarti, Debalay

    2016-01-01

    Cold-rolled samples of different starting microstructures, namely ferrite-pearlite (F+P) and ferrite-martensite structures, with blocky martensite (F+Mb) and fibrous martensite (F+Mf) morphologies were reheated at two different heating rates (1 and 300 K/s) to sub-critical and inter-critical annealing temperatures [773 K to 1173 K (500 °C to 900 °C)] and immediately water quenched. Grain refinement after annealing of cold-rolled samples depends on the rate of recovery, recrystallization, transformation, and grain growth. Rapid recrystallization during annealing weakened the recrystallization-transformation interaction in F+P sample. Higher rate of ferrite recovery reduced the driving force for recrystallization, which weakened the recrystallization-transformation interaction during annealing of F+Mb sample. As a result, coarser grain structures were obtained after annealing of cold-rolled F+P and F+Mb starting structures. Strong recrystallization-transformation interaction and suppression of grain growth by uniformly distributed carbide particles and austenite islands (after transformation) offered finest ferrite grain size and best combination of strength and ductility in F+Mf sample.

  19. Fabrication and testing of an enhanced ignition system to reduce cold-start emissions in an ethanol (E85) light-duty truck engine

    SciTech Connect

    Gardiner, D; Mallory, R; Todesco, M

    1997-09-01

    This report describes an experimental investigation of the potential for an enhanced ignition system to lower the cold-start emissions of a light-duty vehicle engine using fuel ethanol (commonly referred to as E85). Plasma jet ignition and conventional inductive ignition were compared for a General Motors 4-cylinder, alcohol-compatible engine. Emission and combustion stability measurements were made over a range of air/fuel ratios and spark timing settings using a steady-state, cold-idle experimental technique in which the engine coolant was maintained at 25 C to simulate cold-running conditions. These tests were aimed at identifying the degree to which calibration strategies such as mixture enleanment and retarded spark timing could lower engine-out hydrocarbon emissions and raise exhaust temperatures, as well as determining how such calibration changes would affect the combustion stability of the engine (as quantified by the coefficient of variation, or COV, of indicated mean effective pressure calculated from successive cylinder pressure measurements). 44 refs., 39 figs.

  20. Improved bonding strength of bioactive cermet Cold Gas Spray coatings.

    PubMed

    Gardon, M; Concustell, A; Dosta, S; Cinca, N; Cano, I G; Guilemany, J M

    2014-12-01

    The fabrication of cermet biocompatible coatings by means Cold Gas Spray (CGS) provides prosthesis with outstanding mechanical properties and the required composition for enhancing the bioactivity of prosthetic materials. In this study, hydroxyapatite/Titanium coatings were deposited by means of CGS technology onto titanium alloy substrates with the aim of building-up well-bonded homogeneous coatings. Powders were blended in different percentages and sprayed; as long as the amount of hydroxyapatite in the feedstock increased, the quality of the coating was reduced. Besides, the relation between the particle size distribution of ceramic and metallic particles is of significant consideration. Plastic deformation of titanium particles at the impact eased the anchoring of hard hydroxyapatite particles present at the top surface of the coating, which assures the looked-for interaction with the cells. Coatings were immersed in Hank's solution for 1, 4 and 7 days; bonding strength value was above 60 MPa even after 7 days, which enhances common results of HAp coatings obtained by conventional thermal spray technologies. PMID:25491809

  1. Start-up improvement in turbine mode for high head PSP machine

    NASA Astrophysics Data System (ADS)

    Houdeline, J. B.; Liu, J.; Lavigne, S.; Laurant, Y.; Balara, L.

    2012-11-01

    Pumped Storage Plants (PSP) using reversible pump-turbines are today the most efficient way of storing large amounts of electrical energy at acceptable costs. However, in order to suit high and sudden variations in power demand, a large amount of power must be available to be released quickly at the required time. When peak power production is required, then start-up in turbine mode must be fast, efficient and reliable. During start-up, the machine must operate at a stable speed close to the no-load condition (i.e. close to the runaway characteristic) while all synchronized guide vanes are open slightly. This is very challenging for high head units that can have an S-shaped characteristic in the turbine quadrant close to the no load condition. This paper focuses on a new hydraulic design that provides an improvement of the S-shaped characteristic and thus removes all speed instability sources during the start-up sequence of the turbine in a large operating head range while not involving a special stabilizing technique. Hydraulic design is fundamental for any PSP. Given the constraints in generating and pumping modes, S-shaped phenomena become even more important and then more difficult to be mastered for high head machines. Thanks to the pump-turbine design methodology, the use of CFD tools as well as model tests for optimization, a dedicated high head pump-turbine design was developed to achieve a significant improvement of the S-shaped characteristic using all synchronized guide vanes. This paper describes the S-shaped phenomena from a hydraulic point of view. We also detail the numerical study, the model tests results and the turbine coupling sequence simulation results for which a comparison is done between a typical high head design and a dedicated high head design to the S-shaped reduction.

  2. Comparative photosynthetic and metabolic analyses reveal mechanism of improved cold stress tolerance in bermudagrass by exogenous melatonin.

    PubMed

    Hu, Zhengrong; Fan, Jibiao; Xie, Yan; Amombo, Erick; Liu, Ao; Gitau, Margaret Mukami; Khaldun, A B M; Chen, Liang; Fu, Jinmin

    2016-03-01

    Melatonin (N-acetyl-5-methoxytryptamine) has been reported to participate in plant development and abiotic stress responses. The main objective of this study was to investigate the role of melatonin in the cold-sensitive (S) and the cold-tolerant (T) bermudagrass genotypes' response to cold stress. The genotypes were treated with 100 μM melatonin and exposed to 4 °C temperature for 3 days. In both genotypes, cold stress increased the endogenous melatonin levels, and more prominently in T than S. Physiological responses indicated that exogenous melatonin triggered antioxidant activities in both genotypes, while it alleviated cell damage in the T genotype response to cold stress. Melatonin treatment under cold stress increased fluorescence curve levels for both genotypes, and higher in T than S genotypes. In both genotypes, the alterations in photosynthetic fluorescence parameters after melatonin treatment highlighted the participation of melatonin in improving photosystem response to cold stress, particularly for the cold-tolerant genotype. The metabolic analyses revealed the alterations of 44 cold-responsive metabolites in the two genotypes, mainly including carbohydrates, organic acids and amino acids. After exogenous melatonin treatment under cold condition, there was high accumulation of metabolites in the cold-tolerant regimes than their cold-sensitive counterparts. Collectively, the present study revealed differential modulations of melatonin between the cold-sensitive and the cold-tolerant genotypes in response to cold stress. This was mainly by impacting antioxidant system, photosystem II, as well as metabolic homeostasis. PMID:26807934

  3. Finishing big by starting small. Continuous improvement is the key to enhancing community health.

    PubMed

    Knapp, M L

    1997-01-01

    Although healthcare organizations increasingly seek involvement in community health improvement, they are often unprepared to do so because of their inexperience in disease and injury prevention. In recent years, however, continuous improvement (Cl) methodology has produced insights that are useful in such projects. An organization considering a community health improvement project should, from the start, test it through "Plan, Do, Study, Act" (PDSA) cycles. The project's leaders should begin by selecting an issue to work on. They must accurately define the community and involve its members in the project, because health improvement work is most effective when the people who care most strongly about a problem help solve it. Leaders should clearly define the project's aim, perhaps through analyzing hospital records and other databases. In forming a collaborative group to work on the project, leaders should begin with a "core team," perhaps adding other members later. This team should track data using three kinds of measurement--global, intermediate, and process--building data evaluation into its daily practices. The team would do well to get the guidance of someone familiar with Cl methodology. It should also use a process involving regular meetings, time lines, a means of communicating with experts outside the area, and a format that enables it to document progress and capture lessons learned. PMID:10173536

  4. Extended alternating-temperature cold acclimation and culture duration improve pear shoot cryopreservation.

    PubMed

    Chang, Y; Reed, B M

    2000-06-01

    Meristems of many pear genotypes can be successfully cryopreserved following 1 week of cold acclimation, but an equal number do not survive the process or have very little regrowth. This study compared commonly used cold acclimation protocols to determine whether the cold acclimation technique used affected the cold hardiness of shoots or the regrowth of cryopreserved meristems. In vitro-grown pear (Pyrus L.) shoots were cold acclimated for up to 16 weeks, then either the shoot tips were tested for cold hardiness or the meristems were cryopreserved by controlled freezing. Cold acclimation consisted of alternating temperatures (22 degrees C with light/-1 degrees C darkness with various photo- and thermoperiods) or a constant temperature (4 degrees C with an 8-h photoperiod or darkness). Compared with nonacclimated controls, both alternating- and constant-temperature acclimation significantly improved postcryopreservation regrowth of P. cordata Desv. and P. pashia Buch. -Ham. ex D. Don meristems. Alternating-temperature acclimation combined with either an 8-h photoperiod or darkness was significantly better than constant-temperature acclimation. Alternating-temperature shoot acclimation for 2 to 5 weeks significantly increased postcryopreservation meristem regrowth, and recovery remained high for up to 15 weeks acclimation. Postcryopreservation meristem regrowth increased with 1 to 5 weeks of constant-temperature acclimation and then declined with longer acclimation. Shoot cold hardiness varied with the acclimation procedure. The LT(50) of shoots acclimated for 10 weeks with alternating temperatures was -25 degrees C; that with constant temperature was -14.7 degrees C; and that of the nonacclimated control was -10 degrees C. Less frequent transfer of cultures also improved acclimation of shoots. Shoots grown without transfer to fresh medium for 6-12 weeks had higher postcryopreservation recovery with shorter periods of acclimation than shoots with a 3-week transfer

  5. Genetic improvement of rainbow trout at the National Center for Cool and Cold Water Aquaculture

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A major constraint to increasing the efficiency of rainbow trout production is the lack of well-characterized, genetically-improved stocks. Scientists at the USDA, ARS, National Center for Center for Cool and Cold Water Aquaculture have developed two resource populations suitable for long-term sele...

  6. Improving Instruction in Head Start Preschool Classrooms through Feedback and Support to Teachers

    ERIC Educational Resources Information Center

    Boat, Mary B.; Carr, Victoria; Barnett, David; Macmann, Gregg; Moomaw, Sally; Pan, Wei; Nichols, Angela

    2009-01-01

    This article discusses the use of data-based feedback and support to teachers in Head Start classrooms to facilitate increased use of effective instructional and managerial practices. The authors conducted a study to examine the impact of providing Head Start preschool classroom teachers with data regarding their use of established instructional…

  7. An Integrated Curriculum to Improve Mathematics, Language, and Literacy for Head Start Children

    ERIC Educational Resources Information Center

    Fantuzzo, John W.; Gadsden, Vivian L.; McDermott, Paul A.

    2011-01-01

    This article reports on the development and field trial of an integrated Head Start curriculum (Evidence-Based Program for Integrated Curricula [EPIC]) that focuses on comprehensive mathematics, language, and literacy skills. Seventy Head Start classrooms (N = 1,415 children) were randomly assigned to one of two curriculum programs: EPIC or the…

  8. Improving the odds: Influence of starting pools on in vitro selection outcomes.

    PubMed

    Pobanz, Kelsey; Lupták, Andrej

    2016-08-15

    As with any outcome of an evolutionary process, the success of in vitro selection experiments depends critically on the starting population. In vitro selections isolate functional nucleic acids that fold into specific structures and form unique binding and catalytic sites. The selection outcomes therefore depend on the molecular and structural diversity of the initial pools. In addition, the experiments are strongly influenced by the length of the starting pool. Longer randomized regions support the formation of more complex structures and presumably allow formation of more intricate tertiary interactions, but they also tend to misfold and aggregate, whereas shorter pools are sufficient to yield simpler motifs. Furthermore, introducing a sequence bias that promotes secondary structure formation appears to prejudice the population towards more functional macromolecules. We review the literature on the influence of the starting pools on the predicted and actual outcomes of laboratory evolution experiments. PMID:27109058

  9. A Professional Development Program to Improve Math Skills among Preschool Children in Head Start

    ERIC Educational Resources Information Center

    Brendefur, Jonathan; Strother, Sam; Thiede, Keith; Lane, Cristianne; Surges-Prokop, Mary Jo

    2013-01-01

    The purpose of this study was to examine the effects on four-year-olds' knowledge of mathematics by introducing professional development and center-based mathematics activities around four mathematical domains to early educators' teaching in Head Start programs. Because of the need to provide necessary mathematical experiences to young children to…

  10. Exhaust emissions of volatile organic compounds of powered two-wheelers: effect of cold start and vehicle speed. Contribution to greenhouse effect and tropospheric ozone formation.

    PubMed

    Costagliola, M Antonietta; Murena, Fabio; Prati, M Vittoria

    2014-01-15

    Powered two-wheeler (PTW) vehicles complying with recent European type approval standards (stages Euro 2 and Euro 3) were tested on chassis dynamometer in order to measure exhaust emissions of about 25 volatile organic compounds (VOCs) in the range C1-C7, including carcinogenic compounds as benzene and 1,3-butadiene. The fleet consists of a moped (engine capacity ≤ 50 cm(3)) and three fuel injection motorcycles of different engine capacities (150, 300 and 400 cm(3)). Different driving conditions were tested (US FPT cycle, constant speed). Due to the poor control of the combustion and catalyst efficiency, moped is the highest pollutant emitter. In fact, fuel injection strategy and three way catalyst with lambda sensor are able to reduce VOC motorcycles' emission of about one order of magnitude with respect to moped. Cold start effect, that is crucial for the assessment of actual emission of PTWs in urban areas, was significant: 30-51% of extra emission for methane. In the investigated speed range, moped showed a significant maximum of VOC emission factor at minimum speed (10 km/h) and a slightly decreasing trend from 20 to 60 km/h; motorcycles showed on the average a less significant peak at 10 km/h, a minimum at 30-40 km/h and then an increasing trend with a maximum emission factor at 90 km/h. Carcinogenic VOCs show the same pattern of total VOCs. Ozone Formation Potential (OFP) was estimated by using Maximum Incremental Reactivity scale. The greatest contribution to tropospheric ozone formation comes from alkenes group which account for 50-80% to the total OFP. VOC contribution effect on greenhouse effect is negligible with respect to CO2 emitted. PMID:24095967

  11. [Improving drug prescribing in the elderly: a new edition of STOPP/START criteria].

    PubMed

    Delgado Silveira, E; Montero Errasquín, B; Muñoz García, M; Vélez-Díaz-Pallarés, M; Lozano Montoya, I; Sánchez-Castellano, C; Cruz-Jentoft, A J

    2015-01-01

    Inappropriate use of drugs in older patients may have an adverse impact on several individual health outcomes, such as increasing the prevalence of adverse drug reactions, morbidity and mortality, and geriatric syndromes, as well as on health care systems, such as increased costs and longer hospital stays. Explicit criteria of drug appropriateness are increasingly used to detect and prevent inappropriate use of drugs, either within a comprehensive geriatric assessment or as tool used by different multidisciplinary geriatric teams. STOPP-START criteria, first published in 2008 (in Spanish in 2009), are being adopted as reference criteria throughout Europe. The Spanish version of the new 2014 edition (recently published in English) of the STOPP-START criteria is presented here. A review of all the papers published in Spain using the former version of these criteria is also presented, with the intention of promoting their use and for research in different health care levels. PMID:25466971

  12. Improvement of Cold Tolerance by Selective A1 Adenosine Receptor Antagonists in Rats

    PubMed Central

    Lee, T. F.; Li, D. J.; Jacobson, K. A.; Wang, L. C. H.

    2015-01-01

    Previously we have shown that the improvement of cold tolerance by theophylline is due to antagonism at adenosine receptors rather than inhibition of phosphodiesterase. Since theophylline is a nonselective adenosine receptor antagonist for both A1 and A2 receptors, the present study investigated the adenosine receptor subtype involved in theophylline’s action. Acute systemic injection of selective A1 receptor antagonists (1,3-dialkyl-8-aryl or 1,3-dialkyl-8-cyclopentyl xanthine derivatives) significantly increased both the total and maximal heat production as well as cold tolerance. In contrast, injection of a relatively selective A2 receptor antagonist, 3,7-dimethyl-1-propargylxanthine (compound No. 19), failed to significantly alter the thermogenic response of the rat under cold exposure. Further, the relative effectiveness of these compounds in increasing total thermogenesis was positively correlated with their potency in blocking the A1 adenosine receptor (r= .52, p<0.01), but not in A2 adenosine receptor (r= .20, p<0.2). It is likely that the thermally beneficial effects of adenosine A1 antagonists are due to their attenuation of the inhibitory effects of endogenously released adenosine on lipolysis and glucose utilization, resulting in increased substrate mobilization and utilization for enhanced thermogenesis. PMID:2263650

  13. The Starting Early Starting Smart Integrated Services Model: Improving Access to Behavioral Health Services in the Pediatric Health Care Setting for At-Risk Families with Young Children

    ERIC Educational Resources Information Center

    Morrow, Connie E.; Mansoor, Elana; Hanson, K. Lori; Vogel, April L.; Rose-Jacobs, Ruth; Genatossio, Carolyn Seval; Windham, Amy; Bandstra, Emmalee S.

    2010-01-01

    We evaluated the Starting Early Starting Smart (SESS) national initiative to integrate behavioral health services (parenting, mental health, and drug treatment) into the pediatric health care setting for families with young children. Data are presented from five pediatric care (PC) sites, drawing from families at risk due to demographic and…

  14. Improvement of cold-wire response for measurement of temperature dissipation

    NASA Astrophysics Data System (ADS)

    Lemay, J.; Benaïssa, A.

    This work aimed at improving fine-scale measurements using cold-wire anemometry. The dissipation ɛθ of the temperature variance was measured on the axis of a heated turbulent round jet. The measurements were performed with a constant current anemometer (CCA) operating fine Pt-10%Rh wires at very low overheat. The CCA developed for this purpose allowed the use of the current injection method in order to estimate the time constant of the wire. In the first part of the paper, it is shown that the time constants obtained for two wire diameters -d=1.2 and d=0.58μm - compare well with those measured at the same time using two other methods (laser excitation and pulsed wire). Moreover, for these two wires, the estimated time constants were in good agreement with those obtained from a semi-empirical relation. In the second part of the paper, a compensation procedure - post-processing filtering - was developed in order to improved the frequency response of the cold-wire probes. The measurements carried out on the axis of the jet (ReD=16500, Reλ = 167) showed that the frequency response of the 1.2μm wire was significantly improved. In fact, the spectral characteristics of the compensated signal obtained with the 1.2μm wire compared fairly well with those from the 0.58μm wire. Moreover, the results indicated that the compensation procedure must be applied when the cut-off frequency of the cold-wire fc is lower than two times the Kolmogorov frequency fK. In the case where fc = 0.6fK, the compensation procedure can reduce the error in the estimate of ɛθ by more than 20%. When fc = 2fK, the effect of the compensation is reduced to about 5%.

  15. Early gonadotropin-releasing hormone antagonist start improves follicular synchronization and pregnancy outcome as compared to the conventional antagonist protocol

    PubMed Central

    Park, Chan Woo; Hwang, Yu Im; Koo, Hwa Seon; Kang, Inn Soo; Yang, Kwang Moon

    2014-01-01

    Objective To assess whether an early GnRH antagonist start leads to better follicular synchronization and an improved clinical pregnancy rate (CPR). Methods A retrospective cohort study. A total of 218 infertile women who underwent IVF between January 2011 and February 2013. The initial cohort (Cohort I) that underwent IVF between January 2011 and March 2012 included a total of 68 attempted IVF cycles. Thirty-four cycles were treated with the conventional GnRH antagonist protocol, and 34 cycles with an early GnRH antagonist start protocol. The second cohort (Cohort II) that underwent IVF between June 2012 and February 2013 included a total of 150 embryo-transfer (ET) cycles. Forty-three cycles were treated with the conventional GnRH antagonist protocol, 34 cycles with the modified early GnRH antagonist start protocol using highly purified human menopause gonadotropin and an addition of GnRH agonist to the luteal phase support, and 73 cycles with the GnRH agonist long protocol. Results The analysis of Cohort I showed that the number of mature oocytes retrieved was significantly higher in the early GnRH antagonist start cycles than in the conventional antagonist cycles (11.9 vs. 8.2, p=0.04). The analysis of Cohort II revealed higher but non-significant CPR/ET in the modified early GnRH antagonist start cycles (41.2%) than in the conventional antagonist cycles (30.2%), which was comparable to that of the GnRH agonist long protocol cycles (39.7%). Conclusion The modified early antagonist start protocol may improve the mature oocyte yield, possibly via enhanced follicular synchronization, while resulting in superior CPR as compared to the conventional antagonist protocol, which needs to be studied further in prospective randomized controlled trials. PMID:25599038

  16. Improving Snow Measurement Technology to Better Parameterise Cold Regions Hydrometeorology Models

    NASA Astrophysics Data System (ADS)

    Pomeroy, J.; Debeer, C.; Ellis, C.; Essery, R.; Helgason, W.; Kinar, N.; Link, T.; MacDonald, J.

    2008-12-01

    Marmot Creek Research Basin, in the Rocky Mountains of Alberta, Canada constitutes a long term cold regions hydrometeorological observatory with over 45 years of intensive observations in alpine and forested zones. Recently, novel combinations of measurement technology to snow have been deployed in Marmot Creek to advance the understanding of snow processes and to improve hydrometeorological models of streamflow and atmospheric variables. One advance has been the development and application of portable acoustic reflectometry to measure the density and structure of seasonal snowpacks using an audible sound wave. This has permitted the non-invasive measurement of snow water equivalent for both stationary and snow survey applications. Another advance has been the use of oblique time-lapse digital photography which is corrected for elevation and view angle from a LiDAR DEM to produce daily orthogonal snow covered area images of the alpine zone. These images are used to calculate snowcovered area and to develop and test improved snowcover melt and depletion algorithms. Deployment of 3-axis ultrasonic anemometers and fast hygrometers with collection of 10 Hz data and full correction for non-stationarity, axis rotation and other effects has shown that horizontal turbulence is often advected into mountain clearings and causes failure of traditional bulk transfer calculations of latent and sensible heat. For forest snow a hanging, weighed spruce tree and hanging, weighed sub-canopy troughs are used to capture intercepted snow load and unloaded snow fluxes respectively. These quantities provide the information needed to test detailed models of the snow interception and unloading processes. To quantify variations in sub-canopy energy for snowmelt, infrared imaging radiometers and narrow beam radiometers are used to measure thermal radiation exitance from needles, stems and trunks in forests of varying structure. These measurements are being used to develop improved models of

  17. Cold-atmospheric pressure plasma polymerization of acetylene on wood flour for improved wood plastics composites

    NASA Astrophysics Data System (ADS)

    Lekobou, William; Pedrow, Patrick; Englund, Karl; Laborie, Marie-Pierre

    2009-10-01

    Plastic composites have become a large class of construction material for exterior applications. One of the main disadvantages of wood plastic composites resides in the weak adhesion between the polar and hydrophilic surface of wood and the non-polar and hydrophobic polyolefin matrix, hindering the dispersion of the flour in the polymer matrix. To improve interfacial compatibility wood flour can be pretreated with environmentally friendly methods such as cold-atmospheric pressure plasma. The objective of this work is therefore to evaluate the potential of plasma polymerization of acetylene on wood flour to improve the compatibility with polyolefins. This presentation will describe the reactor design used to modify wood flour using acetylene plasma polymerization. The optimum conditions for plasma polymerization on wood particles will also be presented. Finally preliminary results on the wood flour surface properties and use in wood plastic composites will be discussed.

  18. The USDA Animal Improvement Programs Laboratory: A century old and just getting started

    Technology Transfer Automated Retrieval System (TEKTRAN)

    In 1908, USDA's Bureau of Animal Industry began national organization of regional cow testing associations, which led to the development of national Dairy Herd Improvement Association (DHIA). Data recording and progeny testing were closely connected, and early USDA work helped introduce and advance ...

  19. Improved Arterial Blood Oxygenation Following Intravenous Infusion of Cold Supersaturated Dissolved Oxygen Solution

    PubMed Central

    Grady, Daniel J; Gentile, Michael A; Riggs, John H; Cheifetz, Ira M

    2014-01-01

    BACKGROUND One of the primary goals of critical care medicine is to support adequate gas exchange without iatrogenic sequelae. An emerging method of delivering supplemental oxygen is intravenously rather than via the traditional inhalation route. The objective of this study was to evaluate the gas-exchange effects of infusing cold intravenous (IV) fluids containing very high partial pressures of dissolved oxygen (>760 mm Hg) in a porcine model. METHODS Juvenile swines were anesthetized and mechanically ventilated. Each animal received an infusion of cold (13 °C) Ringer’s lactate solution (30 mL/kg/hour), which had been supersaturated with dissolved oxygen gas (39.7 mg/L dissolved oxygen, 992 mm Hg, 30.5 mL/L). Arterial blood gases and physiologic measurements were repeated at 15-minute intervals during a 60-minute IV infusion of the supersaturated dissolved oxygen solution. Each animal served as its own control. RESULTS Five swines (12.9 ± 0.9 kg) were studied. Following the 60-minute infusion, there were significant increases in PaO2 and SaO2 (P < 0.05) and a significant decrease in PaCO2 (P < 0.05), with a corresponding normalization in arterial blood pH. Additionally, there was a significant decrease in core body temperature (P < 0.05) when compared to the baseline preinfusion state. CONCLUSIONS A cold, supersaturated dissolved oxygen solution may be intravenously administered to improve arterial blood oxygenation and ventilation parameters and induce a mild therapeutic hypothermia in a porcine model. PMID:25249764

  20. Improving cold storage and processing traits in potato through targeted gene knockout.

    PubMed

    Clasen, Benjamin M; Stoddard, Thomas J; Luo, Song; Demorest, Zachary L; Li, Jin; Cedrone, Frederic; Tibebu, Redeat; Davison, Shawn; Ray, Erin E; Daulhac, Aurelie; Coffman, Andrew; Yabandith, Ann; Retterath, Adam; Haun, William; Baltes, Nicholas J; Mathis, Luc; Voytas, Daniel F; Zhang, Feng

    2016-01-01

    Cold storage of potato tubers is commonly used to reduce sprouting and extend postharvest shelf life. However, cold temperature stimulates the accumulation of reducing sugars in potato tubers. Upon high-temperature processing, these reducing sugars react with free amino acids, resulting in brown, bitter-tasting products and elevated levels of acrylamide--a potential carcinogen. To minimize the accumulation of reducing sugars, RNA interference (RNAi) technology was used to silence the vacuolar invertase gene (VInv), which encodes a protein that breaks down sucrose to glucose and fructose. Because RNAi often results in incomplete gene silencing and requires the plant to be transgenic, here we used transcription activator-like effector nucleases (TALENs) to knockout VInv within the commercial potato variety, Ranger Russet. We isolated 18 plants containing mutations in at least one VInv allele, and five of these plants had mutations in all VInv alleles. Tubers from full VInv-knockout plants had undetectable levels of reducing sugars, and processed chips contained reduced levels of acrylamide and were lightly coloured. Furthermore, seven of the 18 modified plant lines appeared to contain no TALEN DNA insertions in the potato genome. These results provide a framework for using TALENs to quickly improve traits in commercially relevant autotetraploid potato lines. PMID:25846201

  1. Molecular physiology and breeding at the crossroads of cold hardiness improvement.

    PubMed

    Castonguay, Yves; Dubé, Marie-Pier; Cloutier, Jean; Bertrand, Annick; Michaud, Réal; Laberge, Serge

    2013-01-01

    Alfalfa (Medicago sativa L.) is a major forage legume grown extensively worldwide with important agronomic and environmental attributes. Insufficient cold hardiness is a major impediment to its reliable production in northern climates. Improvement of freezing tolerance using conventional breeding approaches is slowed by the quantitative nature of inheritance and strong interactions with the environment. The development of gene-based markers would facilitate the identification of genotypes with superior stress tolerance. Successive cycles of recurrent selection were applied using an indoor screening method to develop populations with significantly higher tolerance to freezing (TF). Bulk segregant analysis of heterogeneous TF populations identified DNA variations that are progressively enriched in frequency in response to selection. Polymorphisms resulting from intragenic variations within a dehydrin gene were identified and could potentially lead to the development of robust selection tools. Our results illustrate the benefits of feedback interactions between germplasm development programs and molecular physiology for a deeper understanding of the molecular and genetic bases of cold hardiness. PMID:22452626

  2. Does a Non-Circular Chainring Improve Performance in the Bicycle Motocross Cycling Start Sprint?

    PubMed Central

    Mateo-March, Manuel; Fernández-Peña, Eneko; Blasco-Lafarga, Cristina; Morente-Sánchez, Jaime; Zabala, Mikel

    2014-01-01

    Maximising power output during the initial acceleration phase of a bicycle motocross (BMX) race increases the chance to lead the group for the rest of the race. The purpose of this study was to investigate the effect of non-circular chainrings (Q-ring) on performance during the initial acceleration phase of a BMX race. Sixteen male cyclists (Spanish National BMX team) performed two counterbalanced and randomized initial sprints (3.95s), using Q- ring vs. circular chainring, on a BMX track. The sample was divided into two different groups according to their performance (Elite; n = 8 vs. Cadet; n = 8). Elite group covered a greater distance using Q-ring (+0.26 m, p = 0.02; D = 0.23), whilst the improvement for the Cadet (+0.04 m) was not significant (p = 0.87; D = -0.02). Also, there was no significant difference in power output for the Elite group, while the Cadet group revealed larger peak power with the circular chainring. Neither lactate level, nor heart rate showed significant differences due to the different chainring used. The non-circular chainring improved the initial acceleration capacity only in the Elite riders. Key Points This work provides novel results demonstrating very significant improvements in the sprint performance of BMX cycling discipline using a non-circular chainring system. This study seeks a practical application from scientific analysis All data are obtained in a real context of high competition using a sample comprised by the National Spanish Team. Some variables influencing performance as subjects’ physical fitness are discussed. Technical equipment approved by International Cycling Union is studied to check its potentially beneficial influence on performance. PMID:24570612

  3. Does a non-circular chainring improve performance in the bicycle motocross cycling start sprint?

    PubMed

    Mateo-March, Manuel; Fernández-Peña, Eneko; Blasco-Lafarga, Cristina; Morente-Sánchez, Jaime; Zabala, Mikel

    2014-01-01

    Maximising power output during the initial acceleration phase of a bicycle motocross (BMX) race increases the chance to lead the group for the rest of the race. The purpose of this study was to investigate the effect of non-circular chainrings (Q-ring) on performance during the initial acceleration phase of a BMX race. Sixteen male cyclists (Spanish National BMX team) performed two counterbalanced and randomized initial sprints (3.95s), using Q- ring vs. circular chainring, on a BMX track. The sample was divided into two different groups according to their performance (Elite; n = 8 vs. Cadet; n = 8). Elite group covered a greater distance using Q-ring (+0.26 m, p = 0.02; D = 0.23), whilst the improvement for the Cadet (+0.04 m) was not significant (p = 0.87; D = -0.02). Also, there was no significant difference in power output for the Elite group, while the Cadet group revealed larger peak power with the circular chainring. Neither lactate level, nor heart rate showed significant differences due to the different chainring used. The non-circular chainring improved the initial acceleration capacity only in the Elite riders. Key PointsThis work provides novel results demonstrating very significant improvements in the sprint performance of BMX cycling discipline using a non-circular chainring system.This study seeks a practical application from scientific analysisAll data are obtained in a real context of high competition using a sample comprised by the National Spanish Team.Some variables influencing performance as subjects' physical fitness are discussed.Technical equipment approved by International Cycling Union is studied to check its potentially beneficial influence on performance. PMID:24570612

  4. Improvement in medium long-term frequency stability of the integrating sphere cold atom clock

    NASA Astrophysics Data System (ADS)

    Liu, Peng; Cheng, Huadong; Meng, Yanling; Wan, Jinyin; Xiao, Ling; Wang, Xiumei; Wang, Yaning; Liu, Liang

    2016-07-01

    The medium-long term frequency stability of the integrating sphere cold atom clock was improved.During the clock operation, Rb atoms were cooled and manipulated using cooling light diffusely reflected by the inner surface of a microwave cavity in the clock. This light heated the cavity and caused a frequency drift from the resonant frequency of the cavity. Power fluctuations of the cooling light led to atomic density variations in the cavity's central area, which increased the clock frequency instability through a cavity pulling effect. We overcame these limitations with appropriate solutions. A frequency stability of 3.5E-15 was achieved when the integrating time ? increased to 2E4 s.

  5. Stimulated Raman adiabatic passage for improved performance of a cold-atom electron and ion source

    NASA Astrophysics Data System (ADS)

    Sparkes, B. M.; Murphy, D.; Taylor, R. J.; Speirs, R. W.; McCulloch, A. J.; Scholten, R. E.

    2016-08-01

    We implement high-efficiency coherent excitation to a Rydberg state using stimulated Raman adiabatic passage in a cold-atom electron and ion source. We achieve an efficiency of 60% averaged over the laser excitation volume with a peak efficiency of 82%, a 1.6 times improvement relative to incoherent pulsed-laser excitation. Using pulsed electric field ionization of the Rydberg atoms we create electron bunches with durations of 250 ps. High-efficiency excitation will increase source brightness, crucial for ultrafast electron diffraction experiments, and coherent excitation to high-lying Rydberg states could allow for the reduction of internal bunch heating and the creation of a high-speed single-ion source.

  6. Mechanical pretreatment improving hemicelluloses removal from cellulosic fibers during cold caustic extraction.

    PubMed

    Li, Jianguo; Liu, Yishan; Duan, Chao; Zhang, Hongjie; Ni, Yonghao

    2015-09-01

    Hemicelluloses removal is a prerequisite for the production of high-quality cellulose (also known as dissolving pulp), and further recovery and utilization of hemicelluloses, which can be considered as a typical Integrated Forest Biorefinery concept. In this paper, a process of combined mechanical refining and cold caustic extraction (CCE), which was applied to a softwood sulfite sample, was investigated. The results showed that the hemicelluloses removal efficiency and selectivity were higher for the combined treatment than that for the CCE alone. The combined treatment can thus decrease the alkali concentration (from 8% to 4%) to achieve a similar hemicelluloses removal. The improved results were due to the fact that the mechanical refining resulted in increases in pore volume and diameter, water retention value (WRV) and specific surface area (SSA), all of which can make positive contributions to the hemicelluloses removal in the subsequent CCE process. PMID:26081626

  7. Enzyme replacement therapy started at birth improves outcome in difficult-to-treat organs in mucopolysaccharidosis I mice.

    PubMed

    Baldo, Guilherme; Mayer, Fabiana Q; Martinelli, Bárbara Z; de Carvalho, Talita G; Meyer, Fabiola S; de Oliveira, Patrícia G; Meurer, Luise; Tavares, Angela; Matte, Ursula; Giugliani, Roberto

    2013-05-01

    Since we previously observed that in patients with mucopolysaccharidosis (MPS) the storage of undegraded glycosaminoglycans (GAG) occurs from birth, in the present study we aimed to compare normal, untreated MPS I mice (knockout for alpha-l-iduronidase-IDUA), and MPS I mice treated with enzyme replacement therapy (ERT, Laronidase, 1.2mg/kg every 2 weeks) started from birth (ERT-neo) or from 2 months of age (ERT-ad). All mice were sacrificed at 6 months. Both treatments were equally effective in normalizing GAG levels in the viscera but had no detectable effect on the joint. Heart function was also improved with both treatments. On the other hand, mice treated from birth presented better outcomes in the difficult-to-treat aortas and heart valves. Surprisingly, both groups had improvements in behavior tests, and normalization of GAG levels in the brain and IDUA injection resulted in detectable levels of enzyme in the brain tissue 1h after administration. ERT-ad mice developed significantly more anti-IDUA-IgG antibodies, and mice that didn't develop antibodies had better performances in behavior tests, indicating that development of antibodies may reduce enzyme bioavailability. Our results suggest that ERT started from birth leads to better outcomes in the aorta and heart valves, as well as a reduction in antibody levels. Some poor vascularized organs, such as the joints, had partial or no benefit and ancillary therapies might be needed for patients. The results presented here support the idea that ERT started from birth leads to better treatment outcomes and should be considered whenever possible, a observation that gains relevance as newborn screening programs are being considered for MPS and other treatable lysosomal storage disorders. PMID:23562162

  8. The development of a bilingual interactive video to improve physical activity and healthful eating in a head start population.

    PubMed

    Piziak, Veronica

    2014-01-01

    The prevalence of obesity in the Hispanic preschool population remains elevated, particularly among children in low income families below the poverty level. Obesity leads to the early onset of metabolic syndrome and Type 2 diabetes. The Head Start population of Texas is largely comprised of this high risk group. Their physical activity level is suboptimal in part due to lack of available outside play areas and time spent watching television and playing sedentary video games. Dietary intake is frequently high in sugar sweetened beverages and low in vegetables. The group is frequently bilingual with limited vocabulary and has not learned to read. Preserving their Mexican American culture is a concern. This article describes the development and assessment of a group of bilingual interactive video interventions to improve age appropriate physical activity while providing basic nutrition education focusing on increasing vegetable and water intake and decreasing sugar sweetened beverages. Suggestions for development and assessment of content were provided by focus groups of Head Start teachers, managers and dietitians in the Texas counties of Bastrop, Hidalgo and McLennon. A demonstration of the videos was conducted in Bastrop County. Teachers, students and managers felt that the videos provided excellent information, improved exercise participation and engaged the children. PMID:25517978

  9. The Development of a Bilingual Interactive Video to Improve Physical Activity and Healthful Eating in a Head Start Population

    PubMed Central

    Piziak, Veronica

    2014-01-01

    The prevalence of obesity in the Hispanic preschool population remains elevated, particularly among children in low income families below the poverty level. Obesity leads to the early onset of metabolic syndrome and Type 2 diabetes. The Head Start population of Texas is largely comprised of this high risk group. Their physical activity level is suboptimal in part due to lack of available outside play areas and time spent watching television and playing sedentary video games. Dietary intake is frequently high in sugar sweetened beverages and low in vegetables. The group is frequently bilingual with limited vocabulary and has not learned to read. Preserving their Mexican American culture is a concern. This article describes the development and assessment of a group of bilingual interactive video interventions to improve age appropriate physical activity while providing basic nutrition education focusing on increasing vegetable and water intake and decreasing sugar sweetened beverages. Suggestions for development and assessment of content were provided by focus groups of Head Start teachers, managers and dietitians in the Texas counties of Bastrop, Hidalgo and McLennon. A demonstration of the videos was conducted in Bastrop County. Teachers, students and managers felt that the videos provided excellent information, improved exercise participation and engaged the children. PMID:25517978

  10. The development of a bilingual interactive video to improve physical activity and healthful eating in a Head Start population.

    PubMed

    Piziak, Veronica

    2014-12-01

    The prevalence of obesity in the Hispanic preschool population remains elevated, particularly among children in low income families below the poverty level.Obesity leads to the early onset of metabolic syndrome and Type 2 diabetes. The Head Start population of Texas is largely comprised of this high risk group. Their physical activity level is suboptimal in part due to lack of available outside play areas and time spent watching television and playing sedentary video games. Dietary intake is frequently high in sugar sweetened beverages and low in vegetables. The group is frequently bilingual with limited vocabulary and has not learned to read. Preserving their Mexican American culture is a concern. This article describes the development and assessment of a group of bilingual interactive video interventions to improve age appropriate physical activity while providing basic nutrition education focusing on increasing vegetable and water intake and decreasing sugar sweetened beverages. Suggestions for development and assessment of content were provided by focus groups of Head Start teachers, managers and dietitians in the Texas counties of Bastrop, Hidalgo and McLennon. A demonstration of the videos was conducted in Bastrop County. Teachers, students and managers felt that the videos provided excellent information, improved exercise participation and engaged the children. PMID:25590094

  11. Cool-season annual grasses interseeded into bermudagrass with improved cold-tolerance for grazing in the upper south

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Bermudagrass [Cynodon dactylon (Pers.) L.] cultivars with improved cold tolerance can be utilized for grazing in the transition zone between the temperate northeast and subtropical southeast, but these bermudagrasses generally do not provide adequate growth for stocking until late May to early June....

  12. Cold Atmospheric Plasma Modified Electrospun Scaffolds with Embedded Microspheres for Improved Cartilage Regeneration.

    PubMed

    Zhu, Wei; Castro, Nathan J; Cheng, Xiaoqian; Keidar, Michael; Zhang, Lijie Grace

    2015-01-01

    Articular cartilage is prone to degeneration and possesses extremely poor self-healing capacity due to inherent low cell density and the absence of a vasculature network. Tissue engineered cartilage scaffolds show promise for cartilage repair. However, there still remains a lack of ideal biomimetic tissue scaffolds which effectively stimulate cartilage regeneration with appropriate functional properties. Therefore, the objective of this study is to develop a novel biomimetic and bioactive electrospun cartilage substitute by integrating cold atmospheric plasma (CAP) treatment with sustained growth factor delivery microspheres. Specifically, CAP was applied to a poly(ε-caprolactone) electrospun scaffold with homogeneously distributed bioactive factors (transforming growth factor-β1 and bovine serum albumin) loaded poly(lactic-co-glycolic) acid microspheres. We have shown that CAP treatment renders electrospun scaffolds more hydrophilic thus facilitating vitronectin adsorption. More importantly, our results demonstrate, for the first time, CAP and microspheres can synergistically enhance stem cell growth as well as improve chondrogenic differentiation of human marrow-derived mesenchymal stem cells (such as increased glycosaminoglycan, type II collagen, and total collagen production). Furthermore, CAP can substantially enhance 3D cell infiltration (over two-fold increase in infiltration depth after 1 day of culture) in the scaffolds. By integrating CAP, sustained bioactive factor loaded microspheres, and electrospinning, we have fabricated a promising bioactive scaffold for cartilage regeneration. PMID:26222527

  13. Cold Atmospheric Plasma Modified Electrospun Scaffolds with Embedded Microspheres for Improved Cartilage Regeneration

    PubMed Central

    Zhu, Wei; Castro, Nathan J.; Cheng, Xiaoqian; Keidar, Michael; Zhang, Lijie Grace

    2015-01-01

    Articular cartilage is prone to degeneration and possesses extremely poor self-healing capacity due to inherent low cell density and the absence of a vasculature network. Tissue engineered cartilage scaffolds show promise for cartilage repair. However, there still remains a lack of ideal biomimetic tissue scaffolds which effectively stimulate cartilage regeneration with appropriate functional properties. Therefore, the objective of this study is to develop a novel biomimetic and bioactive electrospun cartilage substitute by integrating cold atmospheric plasma (CAP) treatment with sustained growth factor delivery microspheres. Specifically, CAP was applied to a poly(ε-caprolactone) electrospun scaffold with homogeneously distributed bioactive factors (transforming growth factor-β1 and bovine serum albumin) loaded poly(lactic-co-glycolic) acid microspheres. We have shown that CAP treatment renders electrospun scaffolds more hydrophilic thus facilitating vitronectin adsorption. More importantly, our results demonstrate, for the first time, CAP and microspheres can synergistically enhance stem cell growth as well as improve chondrogenic differentiation of human marrow-derived mesenchymal stem cells (such as increased glycosaminoglycan, type II collagen, and total collagen production). Furthermore, CAP can substantially enhance 3D cell infiltration (over two-fold increase in infiltration depth after 1 day of culture) in the scaffolds. By integrating CAP, sustained bioactive factor loaded microspheres, and electrospinning, we have fabricated a promising bioactive scaffold for cartilage regeneration. PMID:26222527

  14. Cold habituation does not improve manual dexterity during rest and exercise in 5 °C

    NASA Astrophysics Data System (ADS)

    Muller, Matthew D.; Seo, Yongsuk; Kim, Chul-Ho; Ryan, Edward J.; Pollock, Brandon S.; Burns, Keith J.; Glickman, Ellen L.

    2014-04-01

    When exposed to a cold environment, a barehanded person experiences pain, cold sensation, and reduced manual dexterity. Both acute (e.g. exercise) and chronic (e.g. cold acclimatization or habituation) processes might lessen these negative effects. The purpose of this experiment was to determine the effect of cold habituation on physiology, perception, and manual dexterity during rest, exercise, and recovery in 5 °C. Six cold weather athletes (CWA) and eight non habituated men (NON) volunteered to participate in a repeated measures cross-over design. The protocol was conducted in 5 °C and was 90 min of resting cold exposure, 30 min of cycle ergometry exercise (50 % VO2 peak), and 60 min of seated recovery. Core and finger skin temperature, metabolic rate, Purdue Pegboard dexterity performance, hand pain, thermal sensation, and mood were quantified. Exercise-induced finger rewarming (EIFRW) was calculated for each hand. During 90 min of resting exposure to 5 °C, the CWA had a smaller reduction in finger temperature, a lower metabolic rate, less hand pain, and less negative mood. Despite this cold habituation, dexterity performance was not different between groups. In response to cycle ergometry, EIFRW was greater in CWA (~12 versus 7 °C) and occurred at lower core temperatures (37.02 versus 37.31 °C) relative to NON but dexterity was not greater during post-exercise recovery. The current data indicate that cold habituated men (i.e., CWA) do not perform better on the Purdue Pegboard during acute cold exposure. Furthermore, despite augmented EIFRW in CWA, dexterity during post-exercise recovery was similar between groups.

  15. Improving the Skills and Credentials of Migrant, Seasonal and American Indian/Alaska Native Head Start Teachers: Building from Within

    ERIC Educational Resources Information Center

    Cavanagh, Sean; Singh, Arati; Levine, Pamela

    2010-01-01

    For over four decades, the federal Head Start program has provided millions of young children from impoverished backgrounds with access to early childhood education and basic health services. By some important measures, Head Start has helped put children on the path to academic and economic success. Teachers in the Head Start program play a…

  16. Building America Best Practices Series: Volume 3; Builders and Buyers Handbook for Improving New Home Efficiency, Comfort, and Durability in the Cold and Very Cold Climates

    SciTech Connect

    2005-08-01

    The guide book is a resource to help builders large and small build high-quality, energy-efficient homes that achieve 30% energy savings in space conditioning and water heating in the cold and very cold climates.

  17. Temperature-stable lithium niobate electro-optic Q-switch for improved cold performance

    NASA Astrophysics Data System (ADS)

    Jundt, Dieter H.

    2014-10-01

    Lithium niobate (LN) is commonly used as an electro optic (EO) Q-switch material in infrared targeting lasers because of its relatively low voltage requirements and low cost compared to other crystals. A common challenge is maintaining good performance at the sub-freezing temperatures often experienced during flight. Dropping to low temperature causes a pyro-electric charge buildup on the optical faces that leads to birefringence non-uniformity and depolarization resulting in poor hold-off and premature lasing. The most common solution has been to use radioactive americium to ionize the air around the crystal and bleed off the charge, but the radioactive material requires handling and disposal procedures that can be problematic. We have developed a superior solution that is now being implemented by multiple defense system suppliers. By applying a low level thermo-chemical reduction to the LN crystal optical faces we induce a small conductivity that allows pyro-charges to dissipate. As the material gets more heavily treated, the capacity to dissipate charges improves, but the corresponding optical absorption also increases, causing insertion loss. Even though typical high gain targeting laser systems can tolerate a few percent of added loss, the thermo-chemical processing needs to be carefully optimized. We describe the results of our process optimization to minimize the insertion loss while still giving effective charge dissipation. Treatment is performed at temperatures below 500°C and a conductivity layer less than 0.5mm in depth is created that is uniform across the optical aperture. Because the conductivity is thermally activated, the charge dissipation is less effective at low temperature, and characterization needs to be performed at cold temperatures. The trade-off between optical insertion loss and potential depolarization due to low temperature operation is discussed and experimental results on the temperature dependence of the dissipation time and the

  18. Cold stress improves the ability of Lactobacillus plantarum L67 to survive freezing.

    PubMed

    Song, Sooyeon; Bae, Dong-Won; Lim, Kwangsei; Griffiths, Mansel W; Oh, Sejong

    2014-11-17

    The stress resistance of bacteria is affected by the physiological status of the bacterial cell and environmental factors such as pH, salts and temperature. In this study, we report on the stress response of Lactobacillus plantarum L67 after four consecutive freeze-thaw cycles. The cold stress response of the cold-shock protein genes (cspC, cspL and cspP) and ATPase activities were then evaluated. The cold stress was adjusted to 5 °C when the bacteria were growing at the mid-exponential phase. A comparative proteomic analysis was performed with two-dimensional gel electrophoresis (2D SDS-PAGE) and a matrix assisted laser desorption/ionization-mass spectrometer. Only 56% of the L. plantarum L67 cells without prior exposure to cold stress survived after four consecutive freeze-thaw cycles. However, 78% of the L. plantarum L67 cells that were treated with cold stress at 5 °C for 6 h survived after freeze-thaw conditions. After applying cold stress to the culture for 6h, the cells were then stored for 60 days at 5 °C, 25 °C and 35 °C separately. The cold-stressed culture of L. plantarum L67 showed an 8% higher viability than the control culture. After applying cold stress for 6h, the transcript levels of two genes (cspP and cspL) were up-regulated 1.4 (cspP) and 1.2 (cspL) times compared to the control. However, cspC was not up-regulated. A proteomic analysis showed that the proteins increased after a reduction of the incubation temperature to 5 °C. The importance of the expression of 13 other relevant proteins was also determined through the study. The exposure of L. plantarum cells to low temperatures aids their ability to survive through subsequent freeze-thaw processes and lyophilization. PMID:25261832

  19. Middle Start Schools Striving for Excellence: Steadily Improving High-Poverty Schools in the Mid South Delta

    ERIC Educational Resources Information Center

    Rose, Lea Williams

    2006-01-01

    As part of a national Middle Start initiative led by the Academy for Educational Development (AED), Mid South Middle Start is committed to working with high-poverty schools in the Mid South Delta region to build their capacity to foster students' academic excellence, support the development of young adolescents, and achieve social equity in…

  20. A Program to Improve Teacher Performance in Head Start Classrooms based on a Trainer of Trainers Approach.

    ERIC Educational Resources Information Center

    Wilmshurst, Ann

    This practicum addressed the need to provide training in basic early childhood education subject areas to Head Start teachers and teacher assistants. A trainer of trainers approach was implemented because of the large number of teachers involved (approximately 1,300 in the Los Angeles County Schools Head Start grantee programs). Goals for…

  1. Cold Calling and Web Postings: Do They Improve Students' Preparation and Learning in Statistics?

    ERIC Educational Resources Information Center

    Levy, Dan

    2014-01-01

    Getting students to prepare well for class is a common challenge faced by instructors all over the world. This study investigates the effects that two frequently used techniques to increase student preparation--web postings and cold calling--have on student outcomes. The study is based on two experiments and a qualitative study conducted in a…

  2. Application of COLD-PCR for improved detection of NF2 mosaic mutations.

    PubMed

    Paganini, Irene; Mancini, Irene; Baroncelli, Marta; Arena, Guido; Gensini, Francesca; Papi, Laura; Sestini, Roberta

    2014-07-01

    Somatic mosaicism represents the coexistence of two or more cell populations with different genotypes in one person, and it is involved in >30 monogenic disorders. Somatic mosaicism characterizes approximately 25% to 33% of patients with de novo neurofibromatosis type 2 (NF2). The identification of mosaicism is crucial to patients and their families because the clinical course of the disease and its transmission risk is influenced by the degree and distribution of mutated cells. Moreover, in NF2, the capability of discriminating patients with mosaicism is especially important to make differential diagnosis with schwannomatosis. However, the identification of mosaic variants is considerably difficult, and the development of specific molecular techniques to detect low levels of unknown molecular alterations is required. Co-amplification at lower denaturation temperature (COLD)-PCR has been described as a powerful method to selectively amplify minority alleles from mixtures of wild-type and mutation-containing sequences. Here, we applied COLD-PCR to molecular analysis of patients with NF2 mosaicism. With the use of COLD-PCR, followed by direct sequencing, we were able to detect NF2 mutations in blood DNA of three patients with NF2 mosaicism. Our study has shown the capability of COLD-PCR in enriching low-represented mutated allele in blood DNA sample, making it usable for molecular diagnosis of patients with mosaicism. PMID:24815379

  3. Improving the cold flow properties of biodiesel by skeletal isomerization of fatty acid chains

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Biodiesel is defined as the mono-alkyl fatty acid esters made from vegetable oil or animal fat lipids. Despite its many advantages, biodiesel from most lipid feedstocks has generally poor cold flow properties. The present study evaluates the fuel related properties of branched-chain fatty acid methy...

  4. Improving mechanical properties of polyethylene orthopaedic implants by high frequency cold plasma surface activation

    NASA Astrophysics Data System (ADS)

    Tudoran, Cristian D.; Vlad, Iulia E.; Dadarlat, Dorin N.; Anghel, Sorin D.

    2013-11-01

    Although a tremendous progress has been made in developing new methods and materials for manufacturing orthopaedic implants, the new technology still faces various problems. Polyethylene implants are relatively easy to manufacture and at lower cost compared to metallic or ceramic implants, but they present a fundamental problem: during usage and in time, due to their manufacturing technology, the material suffers from pitting and delamination which leads to crack propagation and finally to sudden fracture. Our studies and tests performed on polyethylene showed that, using cold plasma surface activation during the manufacturing process of the orthopaedic implants made from polyethylene can significantly increase their mechanical properties. The breaking tests revealed an increase of the tensile strength in the laminated polyethylene samples by a factor of 4 after plasma activation. "Aging" tests have been also performed to investigate how the cold plasma treated samples maintain their properties in time, after the surface activation process.

  5. Sure Start

    ERIC Educational Resources Information Center

    Moss, Peter

    2004-01-01

    This paper outlines what is involved in Sure Start, one of New Labour's key social policy interventions. It is argued that there are policy continuities with older redemptive policies which focus on young children. It is also argued that Sure Start could provide a bridgehead for a more socially democratic orientation into early childhood policy.

  6. RuBisCO depletion improved proteome coverage of cold responsive S-nitrosylated targets in Brassica juncea

    PubMed Central

    Sehrawat, Ankita; Abat, Jasmeet K.; Deswal, Renu

    2013-01-01

    Although in the last few years good number of S-nitrosylated proteins are identified but information on endogenous targets is still limiting. Therefore, an attempt is made to decipher NO signaling in cold treated Brassica juncea seedlings. Treatment of seedlings with substrate, cofactor and inhibitor of Nitric-oxide synthase and nitrate reductase (NR), indicated NR mediated NO biosynthesis in cold. Analysis of the in vivo thiols showed depletion of low molecular weight thiols and enhancement of available protein thiols, suggesting redox changes. To have a detailed view, S-nitrosylation analysis was done using biotin switch technique (BST) and avidin-affinity chromatography. Ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) is S-nitrosylated and therefore, is identified as target repeatedly due to its abundance. It also competes out low abundant proteins which are important NO signaling components. Therefore, RuBisCO was removed (over 80%) using immunoaffinity purification. Purified S-nitrosylated RuBisCO depleted proteins were resolved on 2-D gel as 110 spots, including 13 new, which were absent in the crude S-nitrosoproteome. These were identified by nLC-MS/MS as thioredoxin, fructose biphosphate aldolase class I, myrosinase, salt responsive proteins, peptidyl-prolyl cis-trans isomerase and malate dehydrogenase. Cold showed differential S-nitrosylation of 15 spots, enhanced superoxide dismutase activity (via S-nitrosylation) and promoted the detoxification of superoxide radicals. Increased S-nitrosylation of glyceraldehyde-3-phosphate dehydrogenase sedoheptulose-biphosphatase, and fructose biphosphate aldolase, indicated regulation of Calvin cycle by S-nitrosylation. The results showed that RuBisCO depletion improved proteome coverage and provided clues for NO signaling in cold. PMID:24032038

  7. RuBisCO depletion improved proteome coverage of cold responsive S-nitrosylated targets in Brassica juncea.

    PubMed

    Sehrawat, Ankita; Abat, Jasmeet K; Deswal, Renu

    2013-01-01

    Although in the last few years good number of S-nitrosylated proteins are identified but information on endogenous targets is still limiting. Therefore, an attempt is made to decipher NO signaling in cold treated Brassica juncea seedlings. Treatment of seedlings with substrate, cofactor and inhibitor of Nitric-oxide synthase and nitrate reductase (NR), indicated NR mediated NO biosynthesis in cold. Analysis of the in vivo thiols showed depletion of low molecular weight thiols and enhancement of available protein thiols, suggesting redox changes. To have a detailed view, S-nitrosylation analysis was done using biotin switch technique (BST) and avidin-affinity chromatography. Ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) is S-nitrosylated and therefore, is identified as target repeatedly due to its abundance. It also competes out low abundant proteins which are important NO signaling components. Therefore, RuBisCO was removed (over 80%) using immunoaffinity purification. Purified S-nitrosylated RuBisCO depleted proteins were resolved on 2-D gel as 110 spots, including 13 new, which were absent in the crude S-nitrosoproteome. These were identified by nLC-MS/MS as thioredoxin, fructose biphosphate aldolase class I, myrosinase, salt responsive proteins, peptidyl-prolyl cis-trans isomerase and malate dehydrogenase. Cold showed differential S-nitrosylation of 15 spots, enhanced superoxide dismutase activity (via S-nitrosylation) and promoted the detoxification of superoxide radicals. Increased S-nitrosylation of glyceraldehyde-3-phosphate dehydrogenase sedoheptulose-biphosphatase, and fructose biphosphate aldolase, indicated regulation of Calvin cycle by S-nitrosylation. The results showed that RuBisCO depletion improved proteome coverage and provided clues for NO signaling in cold. PMID:24032038

  8. Healthy Start Programa Madrina: A Promotora Home Visiting Outreach and Education Program to Improve Perinatal Health among Latina Pregnant Women

    ERIC Educational Resources Information Center

    Bill, Debra E.; Hock-Long, Linda; Mesure, Maryann; Bryer, Pamela; Zambrano, Neydary

    2009-01-01

    The purpose of this article is to describe the development, implementation, and evaluation of Healthy Start Programa Madrina (HSPM), a home visiting promotora outreach and education program for Latina pregnant women and to present the 10-year findings of the program (1996-2005). Perinatal health disparities continue to persist among low-income…

  9. The Start of Head Start

    ERIC Educational Resources Information Center

    Neugebauer, Roger

    2010-01-01

    The creation of the Head Start program occurred at break-neck speed with many dramatic turns and many colorful players. No one tells the story better than Edward Zigler in "Head Start: The Inside Story of America's Most Successful Educational Experiment"--a detailed and personal, behind the scenes look at the program's inception. From this…

  10. A Resource Guide for Head Start Programs: Moving beyond a Culture of Compliance to a Culture of Continuous Improvement. OPRE Report 2015-02

    ERIC Educational Resources Information Center

    Derrick-Mills, Teresa; Winkler, Mary K.; Healy, Olivia; Greenberg, Erica

    2015-01-01

    Head Start has long focused on assessing and improving program quality to ensure that the children served receive the best possible preparation for school and life. Most research has been focused inside the classroom--the classroom environment, teacher qualifications, and teacher interactions. Of course, the classroom is important because that is…

  11. Coaching as a Key Component in Teachers' Professional Development: Improving Classroom Practices in Head Start Settings. OPRE Report 2012-4

    ERIC Educational Resources Information Center

    Lloyd, Chrrishana M.; Modlin, Emmily L.

    2012-01-01

    Head Start CARES (Classroom-based Approaches and Resources for Emotion and Social Skill Promotion) is a large-scale, national research demonstration that was designed to test the effects of a one-year program aimed at improving pre-kindergarteners' social and emotional readiness for school. To facilitate the delivery of the program, teachers…

  12. Improved management of winter operations to limit subsurface contamination with degradable deicing chemicals in cold regions.

    PubMed

    French, Helen K; van der Zee, Sjoerd E A T M

    2014-01-01

    This paper gives an overview of management considerations required for better control of deicing chemicals in the unsaturated zone at sites with winter maintenance operations in cold regions. Degradable organic deicing chemicals are the main focus. The importance of the heterogeneity of both the infiltration process, due to frozen ground and snow melt including the contact between the melting snow cover and the soil, and unsaturated flow is emphasised. In this paper, the applicability of geophysical methods for characterising soil heterogeneity is considered, aimed at modelling and monitoring changes in contamination. To deal with heterogeneity, a stochastic modelling framework may be appropriate, emphasizing the more robust spatial and temporal moments. Examples of a combination of different field techniques for measuring subsoil properties and monitoring contaminants and integration through transport modelling are provided by the SoilCAM project and previous work. Commonly, the results of flow and contaminant fate modelling are quite detailed and complex and require post-processing before communication and advising stakeholders. The managers' perspectives with respect to monitoring strategies and challenges still unresolved have been analysed with basis in experience with research collaboration with one of the case study sites, Oslo airport, Gardermoen, Norway. Both scientific challenges of monitoring subsoil contaminants in cold regions and the effective interaction between investigators and management are illustrated. PMID:24281673

  13. Cold-start minidiesel engine development

    NASA Astrophysics Data System (ADS)

    Collins, Conrad

    1993-09-01

    Military mission performance in a chemically contaminated environment necessitates the wearing of chemically impermeable protective garments. Soldiers encapsulated in these protective garments will succumb to heat stress in a hot environment. Consequently, a microclimate cooling system is being developed. In the design, a vapor compression cycle chills water which is then circulated over the body to absorb heat via a cooling garment. The engine, the prime mover in the system, is a major component. Commercially available engines of approximately 0.5 hp at 4000 rpm, the required size, include model aircraft engines and small outdoor power equipment (string trimmer) engines. However, these engines do not run on JP-8 or diesel fuel, a requirement for military use. Design, evaluation, and results of three engines are detailed. These include: the potential of a high compression, carbureted, glow plug engine operating on diesel fuel; the potential of a high compression, spark assist, fuel injected engine operating on diesel fuel; and a true high compression, fuel injected engine operating on diesel fuel.

  14. Elevated compartmentalization of Na+ into vacuoles improves salt and cold stress tolerance in sweet potato (Ipomoea batatas).

    PubMed

    Fan, Weijuan; Deng, Gaifang; Wang, Hongxia; Zhang, Hongxia; Zhang, Peng

    2015-08-01

    Salinity and low temperature are the main limiting factors for sweet potato (Ipomoea batatas) growth and agricultural productivity. Various studies have shown that plant NHX-type antiporter plays a crucial role in regulating plant tolerance to salt stress by intracellular Na(+) compartmentalization. The Arabidopsis thaliana AtNHX1 gene that encodes a vacuolar Na(+) /H(+) antiporter was introduced into the sweet potato cultivar Xushu-22 by Agrobacterium-mediated transformation to confer abiotic stress tolerance. Stable insertion of AtNHX1 into the sweet potato genome and its expression was confirmed by Southern blot and reverse transcription-polymerase chain reaction (RT-PCR). A remarkably higher Na(+) /H(+) exchange activity of tonoplast membrane from transgenic sweet potato lines (NOE) in comparison with wild-type (WT) plants confirmed the vacuolar antiporter function in mediating Na(+) /H(+) exchange. Under salt stress, NOE plants accumulated higher Na(+) and K(+) levels in their tissues compared with WT plants, maintaining high K(+) /Na(+) ratios. Consequently, NOE plants showed enhanced protection against cell damage due to the increased proline accumulation, preserved cell membrane integrity, enhanced reactive oxygen species (ROS) scavenging (e.g. increased superoxide dismutase activity), and reduced H2 O2 and malondialdehyde (MDA) production. Moreover, the transgenic plants showed improved cold tolerance through multiple mechanisms of action, revealing the first molecular evidence for NHX1 function in cold response. The transgenic plants showed better biomass production and root yield under stressful conditions. These findings demonstrate that overexpressing AtNHX1 in sweet potato renders the crop tolerant to both salt and cold stresses, providing a greater capacity for the use of AtNHX1 in improving crop performance under combined abiotic stress conditions. PMID:25307930

  15. Towards an improved understanding of strength and anisotropy of cold compacted powder

    NASA Astrophysics Data System (ADS)

    Wang, Wenhai

    The strength of powder compacts after cold compaction is known to be anisotropic, which comes from the directionality of microstructure resulting from initial particle morphology and/or from particle deformation during compaction. Current work focuses on multi-scale numerical analysis of powder compaction with emphasis on the role of interparticle cohesion on post-compaction mechanical properties. At macroscopic level, we applied phenomenological model to describe the mechanical behavior of powder, in which the material is considered to be continuum medium. A user subroutine (VUMAT) was successfully developed for ABAQUS/Explicit analysis, in which one of the popular phenomenological models for powder compaction---Drucker Prager/Cap model---is implemented. By studying of pharmaceutical powder die compaction and subsequent diametrical compression test via finite element analysis, the capabilities and limitations of current constitutive models are evaluated on predicting such as density, stress and tool force evolution, as well as the strength and fracture tendency. Our results illustrate that current model has good predictive capability of powder densification (e.g. density evolution) but can not predict post-compaction strength well. The following studies focus on evaluating the physics and mechanics occurring at particle level. The compaction of granular media was explored by using MPFEM approach. In the new model, individual particles discretized with a finite element mesh allow for a full description of contact mechanics and local and global particle kinematics. The introduction of a layer of degrading material on the surface of each particle provides the means of introducing variable cohesion and its effect on the final strength of compacts. The simulations show that the unloading creates tensile stresses at the root of the contact necks, which may cause partial or full separation of contact interface when the cohesion developed during loading is not strong

  16. Novel strategy to decrease reperfusion injuries and improve function of cold-preserved livers using normothermic ex vivo liver perfusion machine.

    PubMed

    Banan, Babak; Xiao, Zhenyu; Watson, Rao; Xu, Min; Jia, Jianluo; Upadhya, Gundumi A; Mohanakumar, Thalachallour; Lin, Yiing; Chapman, William

    2016-03-01

    Normothermic extracorporeal liver perfusion (NELP) can decrease ischemia/reperfusion injury to the greatest degree when cold ischemia time is minimized. Warm perfusion of cold-stored livers results in hepatocellular damage, sinusoidal endothelial cell (SEC) dysfunction, and Kupffer cell activation. However, the logistics of organ procurement mandates a period of cold preservation before NELP. The aim of this study was to determine the beneficial effects of gradual rewarming of cold-stored livers by placement on NELP. Three female porcine livers were used for each group. In the immediate NELP group, procured livers were immediately placed on NELP for 8 hours. In the cold NELP group, livers were cold-stored for 4 hours followed by NELP for 4 hours. In rewarming groups, livers were cold-stored for 4 hours, then gradually rewarmed in different durations to 38°C and kept on NELP for an additional 4 hours. For comparison purposes, the last 4 hours of NELP runs were considered to be the evaluation phase. Immediate NELP livers had significantly lower concentrations of liver transaminases, hyaluronic acid, and β-galactosidase and had higher bile production compared to the other groups. Rewarming livers had significantly lower concentrations of hyaluronic acid and β-galactosidase compared to the cold NELP livers. In addition, there was a significant decline in international normalized ratio values, improved bile production, reduced biliary epithelial cell damage, and improved cholangiocyte function. Thus, if a NELP machine is not available at the procurement site and livers will need to undergo a period of cold preservation, a gradual rewarming protocol before NELP may greatly reduce damages that are associated with reperfusion. In conclusion, gradual rewarming of cold-preserved livers upon NELP can minimize the hepatocellular damage, Kupffer cell activation, and SEC dysfunction. PMID:26439190

  17. COLD TRAP

    DOEpatents

    Milleron, N.

    1963-03-12

    An improved linear-flow cold trap is designed for highvacuum applications such as mitigating back migration of diffusion pump oil moiecules. A central pot of liquid nitrogen is nested within and supported by a surrounding, vertical, helical coil of metai sheet, all enveloped by a larger, upright, cylindrical, vacuum vessel. The vertical interstices between successive turns of the coil afford lineal, axial, high-vacuum passages between open mouths at top and bottom of said vessel, while the coil, being cold by virtue of thermal contact of its innermost turn with the nitrogen pot, affords expansive proximate condensation surfaces. (AEC)

  18. Building America Best Practices Series: Volume 3; Builders and Buyers Handbook for Improving New Home Efficiency, Comfort, and Durability in Cold and Very Cold Climates

    SciTech Connect

    Not Available

    2005-08-01

    This best practices guide is part of a series produced by Building America. The guide book is a resource to help builders large and small build high-quality, energy-efficient homes that achieve 30% energy savings in space conditioning and water heating in the cold and very cold climates. The savings are in comparison with the 1993 Model Energy Code. The guide contains chapters for every member of the builder's team-from the manager to the site planner to the designers, site supervisors, the trades, and marketers. There is also a chapter for homeowners on how to use the book to provide help in selecting a new home or builder.

  19. Start Young!

    ERIC Educational Resources Information Center

    Rubin, Penni

    2002-01-01

    Discusses the importance of early interest in science and how effective it is on career choice in adult stages of life. Recommends starting mathematics and science activities in preschool and kindergarten. Describes how to create a career-oriented learning center in the classroom with examples of kitchen chemistry, nutrition/botany, zoology,…

  20. Cold spray deposition of Ti2AlC coatings for improved nuclear fuel cladding

    NASA Astrophysics Data System (ADS)

    Maier, Benjamin R.; Garcia-Diaz, Brenda L.; Hauch, Benjamin; Olson, Luke C.; Sindelar, Robert L.; Sridharan, Kumar

    2015-11-01

    Coatings of Ti2AlC MAX phase compound have been successfully deposited on Zircaloy-4 (Zry-4) test flats, with the goal of enhancing the accident tolerance of LWR fuel cladding. Low temperature powder spray process, also known as cold spray, has been used to deposit coatings ∼90 μm in thickness using powder particles of <20 μm. X-ray diffraction analysis showed the phase-content of the deposited coatings to be identical to the powders indicating that no phase transformation or oxidation had occurred during the coating deposition process. The coating exhibited a high hardness of about 800 HK and pin-on-disk wear tests using abrasive ruby ball counter-surface showed the wear resistance of the coating to be significantly superior to the Zry-4 substrate. Scratch tests revealed the coatings to be well-adhered to the Zry-4 substrate. Such mechanical integrity is required for claddings from the standpoint of fretting wear resistance and resisting wear handling and insertion. Air oxidation tests at 700 °C and simulated LOCA tests at 1005 °C in steam environment showed the coatings to be significantly more oxidation resistant compared to Zry-4 suggesting that such coatings can potentially provide accident tolerance to nuclear fuel cladding.

  1. Cold spray deposition of Ti2AlC coatings for improved nuclear fuel cladding

    NASA Astrophysics Data System (ADS)

    Maier, Benjamin R.; Garcia-Diaz, Brenda L.; Hauch, Benjamin; Olson, Luke C.; Sindelar, Robert L.; Sridharan, Kumar

    2015-11-01

    Coatings of Ti2AlC MAX phase compound have been successfully deposited on Zircaloy-4 (Zry-4) test flats, with the goal of enhancing the accident tolerance of LWR fuel cladding. Low temperature powder spray process, also known as cold spray, has been used to deposit coatings ˜90 μm in thickness using powder particles of <20 μm. X-ray diffraction analysis showed the phase-content of the deposited coatings to be identical to the powders indicating that no phase transformation or oxidation had occurred during the coating deposition process. The coating exhibited a high hardness of about 800 HK and pin-on-disk wear tests using abrasive ruby ball counter-surface showed the wear resistance of the coating to be significantly superior to the Zry-4 substrate. Scratch tests revealed the coatings to be well-adhered to the Zry-4 substrate. Such mechanical integrity is required for claddings from the standpoint of fretting wear resistance and resisting wear handling and insertion. Air oxidation tests at 700 °C and simulated LOCA tests at 1005 °C in steam environment showed the coatings to be significantly more oxidation resistant compared to Zry-4 suggesting that such coatings can potentially provide accident tolerance to nuclear fuel cladding.

  2. Maintaining semen quality by improving cold chain equipment used in cattle artificial insemination

    NASA Astrophysics Data System (ADS)

    Lieberman, Daniel; McClure, Elizabeth; Harston, Stephen; Madan, Damian

    2016-06-01

    Artificial insemination of dairy cattle is a common practice in the developing world that can improve farmer incomes and food security. Maintaining the fertilizing potential of frozen semen as it is manipulated, transported and stored is crucial to the success of this process. Here we describe simple technological improvements to protect semen from inadvertent thermal fluctuations that occur when users mishandle semen using standard equipment. We show that when frozen semen is mishandled, characteristics of semen biology associated with fertility are negatively affected. We describe several design modifications and results from thermal performance tests of several improved prototypes. Finally, we compare semen that has been mishandled in standard and improved equipment. The data suggest that our canister improvements can better maintain characteristics of semen biology that correlate with fertility when it is mishandled.

  3. Maintaining semen quality by improving cold chain equipment used in cattle artificial insemination.

    PubMed

    Lieberman, Daniel; McClure, Elizabeth; Harston, Stephen; Madan, Damian

    2016-01-01

    Artificial insemination of dairy cattle is a common practice in the developing world that can improve farmer incomes and food security. Maintaining the fertilizing potential of frozen semen as it is manipulated, transported and stored is crucial to the success of this process. Here we describe simple technological improvements to protect semen from inadvertent thermal fluctuations that occur when users mishandle semen using standard equipment. We show that when frozen semen is mishandled, characteristics of semen biology associated with fertility are negatively affected. We describe several design modifications and results from thermal performance tests of several improved prototypes. Finally, we compare semen that has been mishandled in standard and improved equipment. The data suggest that our canister improvements can better maintain characteristics of semen biology that correlate with fertility when it is mishandled. PMID:27313137

  4. Maintaining semen quality by improving cold chain equipment used in cattle artificial insemination

    PubMed Central

    Lieberman, Daniel; McClure, Elizabeth; Harston, Stephen; Madan, Damian

    2016-01-01

    Artificial insemination of dairy cattle is a common practice in the developing world that can improve farmer incomes and food security. Maintaining the fertilizing potential of frozen semen as it is manipulated, transported and stored is crucial to the success of this process. Here we describe simple technological improvements to protect semen from inadvertent thermal fluctuations that occur when users mishandle semen using standard equipment. We show that when frozen semen is mishandled, characteristics of semen biology associated with fertility are negatively affected. We describe several design modifications and results from thermal performance tests of several improved prototypes. Finally, we compare semen that has been mishandled in standard and improved equipment. The data suggest that our canister improvements can better maintain characteristics of semen biology that correlate with fertility when it is mishandled. PMID:27313137

  5. Human responses to cold.

    PubMed

    Rintamäki, Hannu

    2007-01-01

    The thermoneutral ambient temperature for naked and resting humans is ca. 27 degrees C. Exposure to cold stimulates cold receptors of the skin which causes cold thermal sensations and stimulation of the sympathetic nervous system. Sympathetic stimulation causes vasoconstriction in skin, arms and legs. Diminished skin and extremity blood flow increases the thermal insulation of superficial tissues more than 300% corresponding to 0.9 clo (0.13 degrees C x m(-2) x W(-1)). With thermoregulatory vasoconstriction/ vasodilatation the body heat balance can be maintained within a range of ca. 4 degrees C, the middle of the range being at ca. 21 degrees C when light clothing is used. Below the thermoneutral zone metabolic heat production (shivering) is stimulated and above the zone starts heat loss by evaporation (sweating). Cold induced vasoconstriction increases blood pressure and viscosity and decreases plasma volume consequently increasing cardiac work. Cold induced hypertensive response can be counteracted by light exercise, while starting heavy work in cold markedly increases blood pressure. Under very cold conditions the sympathetic stimulation opens the anastomoses between arterioles and venules which increases skin temperatures markedly but temporarily, especially in finger tips. Adaptation to cold takes ca. 2 weeks, whereafter the physiological responses to cold are attenuated and cold exposure is subjectively considered less stressful. PMID:17929604

  6. Mapping starting zone snow depth with a ground-based LiDAR to improve avalanche control and forecasting

    NASA Astrophysics Data System (ADS)

    Deems, J. S.; Gadomski, P. J.; Vellone, D.; Evanczyk, R.; LeWinter, A. L.; Birkeland, K.; Finnegan, D. C.

    2014-12-01

    The varying distribution of snow depth in avalanche starting zones exerts a strong influence on avalanche potential and character. Extreme depth changes over short distances are common, especially in wind-affected, above-treeline environments. Snow depth also affects the ease of avalanche triggering. Experience shows that avalanche reduction efforts are often more successful when targeting shallow trigger point areas near deeper slabs with explosives or ski cutting. Our pilot study explores the use of high resolution snow depth and depth change maps from differential LiDAR scans to quantify loading patterns for use in both pre-control planning and in post-control assessment. We present results from our initial work at the Arapahoe Basin Ski Area in Colorado, USA. A-Basin has a large number avalanche starting zones above treeline at elevations up to 4,000 m. The three study areas represent a range of institutional avalanche management history - the East Wall has been operated since 1970, Montezuma Bowl since 2008, and the Steep Gullies are under study for area expansion. Summer mapping produced a zero depth surface. Mapping multiple times during the snow season allowed us to produce time series maps of snow depth and snow depth change at high resolution to explore depth and slab thickness variations due to wind redistribution. We conducted surveys before and after loading events and control work, allowing the exploration of loading patterns, slab thickness, shot and ski cut locations, bed surfaces, entrainment, and avalanche characteristics. We also evaluate the state of terrestrial laser scanning for use in operational settings.

  7. Cold Sores

    MedlinePlus

    ... delivered directly to your desktop! more... What Are Cold Sores? Article Chapters What Are Cold Sores? Cold ... January 2012 Previous Next Related Articles: Canker and Cold Sores Aloe Vera May Help Relieve Mouth Sores ...

  8. Salicylic acid and methyl jasmonate improve chilling tolerance in cold-stored lemon fruit (Citrus limon).

    PubMed

    Siboza, Xolani Irvin; Bertling, Isa; Odindo, Alfred Oduor

    2014-11-15

    Chilling injury (CI) is associated with the degradation of membrane integrity which can be aligned to phenolic oxidation activated by polyphenol oxidase (PPO) and peroxidase (POD), enzymes responsible for tissue browning. Phenylalanine ammonia-lyase (PAL) is a further enzyme prominent in the phenolic metabolism that is involved in acclimation against chilling stress. It was hypothesized that treatment with methyl jasmonate (MJ) and salicylic acid (SA) may enhance chilling tolerance in lemon fruit by increasing the synthesis of total phenolics and PAL by activating the key enzyme regulating the shikimic acid pathway whilst inhibiting the activity of POD and PPO. Lemon fruit were treated with 10μM MJ, 2mM SA or 10μM MJ plus 2mM SA, waxed, stored at -0.5, 2 or 4.5°C for up to 28 days plus 7 days at 23°C. Membrane integrity was studied by investigating membrane permeability and the degree of membrane lipid peroxidation in lemon flavedo following cold storage. The 10μM MJ plus 2mM SA treatment was most effective in enhancing chilling tolerance of lemon fruit, significantly reducing chilling-induced membrane permeability and membrane lipid peroxidation of lemon flavedo tissue. This treatment also increased total phenolics and PAL activity in such tissue while inhibiting POD activity, the latter possibly contributing to the delay of CI manifestation. PPO activity was found to be a poor biochemical marker of CI. Treatment with 10μM MJ plus 2mM SA resulted in an alteration of the phenolic metabolism, enhancing chilling tolerance, possibly through increased production of total phenolics and the activation of PAL and inhibition of POD. PMID:25216124

  9. Press Start

    NASA Astrophysics Data System (ADS)

    Harteveld, Casper

    This level sets the stage for the design philosophy called “Triadic Game Design” (TGD). This design philosophy can be summarized with the following sentence: it takes two to tango, but it takes three to design a meaningful game or a game with a purpose. Before the philosophy is further explained, this level will first delve into what is meant by a meaningful game or a game with a purpose. Many terms and definitions have seen the light and in this book I will specifically orient at digital games that aim to have an effect beyond the context of the game itself. Subsequently, a historical overview is given of the usage of games with a serious purpose which starts from the moment we human beings started to walk on our feet till our contemporary society. It turns out that we have been using games for all kinds of non-entertainment purposes for already quite a long time. With this introductory material in the back of our minds, I will explain the concept of TGD by means of a puzzle. After that, the protagonist of this book, the game Levee Patroller, is introduced. Based on the development of this game, the idea of TGD, which stresses to balance three different worlds, the worlds of Reality, Meaning, and Play, came into being. Interested? Then I suggest to quickly “press start!”

  10. Integrating Low Water Potential Seed Hydration with Other Treatments to Improve Cold Tolerance

    PubMed Central

    Khan, Anwar A.; Ilyas, Satriyas; Ptasznik, Wlodzimierz

    1995-01-01

    Matriconditioning improved the performance of pepper, tomato, sweet corn, snap bean, table beet, sugar beet and watermelon seeds in early field plantings at suboptimal temperatures (averaged over 10 d after planting) ranging from 12 to 18 °C. Reduction in the time to 50% (T50) emergence in conditioned seeds ranged from 0·6 d in watermelon to 3·3 d in pepper and improvement in emergence from 10% in sugar beet to 30% in table beet. Further improvement in emergence occurred by inclusion of pesticides and/or gibberellin during conditioning. A 4 d conditioning of pepper at 25 °C was superior to 7 d conditioning at 15 °C in seeds germinated at 15 °C on filter paper, but 15 °C conditioning was superior in improving percentage emergence in early field plantings. Tomato seeds conditioned at 15 or 25 °C performed equally well in the field. A 2 d conditioning was superior to 1 d conditioning in improving the performance of supersweet sweet corn cultivars grown in a growth chamber at 10/20 °C. The water uptake rate in the presence of Micro-Cel E during matriconditioning of sweet corn seeds was slower than when the seeds were exposed to the same amount of water in absence of the carrier. Electrolyte leakage was greater in supersweet ‘Challenger’ sweet corn seeds carrying the sh2 gene compared to the sugary type sweet corn ‘More’, and in both cases matriconditioning reduced the leakage. Lettuce seeds matriconditioned for 24 h had higher 1-aminocyclopropane-l-carboxylic acid (ACC) content, developed greater ACC oxidase activity and performed better at 10 °C (germinated earlier and had higher percentage germination) than the untreated seeds. Matriconditioning appears to bring about beneficial physical, physiological and biochemical changes that seemingly improve embryo growth potential and tolerance to low temperatures. PMID:21247908

  11. Activated Expression of an Arabidopsis HD-START Protein Confers Drought Tolerance with Improved Root System and Reduced Stomatal Density[W][OA

    PubMed Central

    Yu, Hong; Chen, Xi; Hong, Yuan-Yuan; Wang, Yao; Xu, Ping; Ke, Sheng-Dong; Liu, Hai-Yan; Zhu, Jian-Kang; Oliver, David J.; Xiang, Cheng-Bin

    2008-01-01

    Drought is one of the most important environmental constraints limiting plant growth and agricultural productivity. To understand the underlying mechanism of drought tolerance and to identify genes for improving this important trait, we conducted a gain-of-function genetic screen for improved drought tolerance in Arabidopsis thaliana. One mutant with improved drought tolerance was isolated and designated as enhanced drought tolerance1. The mutant has a more extensive root system than the wild type, with deeper roots and more lateral roots, and shows a reduced leaf stomatal density. The mutant had higher levels of abscisic acid and Pro than the wild type and demonstrated an increased resistance to oxidative stress and high levels of superoxide dismutase. Molecular genetic analysis and recapitulation experiments showed that the enhanced drought tolerance is caused by the activated expression of a T-DNA tagged gene that encodes a putative homeodomain-START transcription factor. Moreover, overexpressing the cDNA of the transcription factor in transgenic tobacco also conferred drought tolerance associated with improved root architecture and reduced leaf stomatal density. Therefore, we have revealed functions of the homeodomain-START factor that were gained upon altering its expression pattern by activation tagging and provide a key regulator that may be used to improve drought tolerance in plants. PMID:18451323

  12. Ethyl levulinate: A potential bio-based diluent for biodiesel which improves cold flow properties

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The physical properties of biodiesel from soybean, canola, cottonseed and poultry fat methyl esters were improved with addition of ethyl levulinate with increasing concentration. The effect of adding ethyl levulinate was determined by studying its influence on the acid value, cloud point, pour point...

  13. Cold temperature improves mobility and survival in Drosophila models of autosomal-dominant hereditary spastic paraplegia (AD-HSP)

    PubMed Central

    Baxter, Sally L.; Allard, Denise E.; Crowl, Christopher; Sherwood, Nina Tang

    2014-01-01

    Autosomal-dominant hereditary spastic paraplegia (AD-HSP) is a crippling neurodegenerative disease for which effective treatment or cure remains unknown. Victims experience progressive mobility loss due to degeneration of the longest axons in the spinal cord. Over half of AD-HSP cases arise from loss-of-function mutations in spastin, which encodes a microtubule-severing AAA ATPase. In Drosophila models of AD-HSP, larvae lacking Spastin exhibit abnormal motor neuron morphology and function, and most die as pupae. Adult survivors display impaired mobility, reminiscent of the human disease. Here, we show that rearing pupae or adults at reduced temperature (18°C), compared with the standard temperature of 24°C, improves the survival and mobility of adult spastin mutants but leaves wild-type flies unaffected. Flies expressing human spastin with pathogenic mutations are similarly rescued. Additionally, larval cooling partially rescues the larval synaptic phenotype. Cooling thus alleviates known spastin phenotypes for each developmental stage at which it is administered and, notably, is effective even in mature adults. We find further that cold treatment rescues larval synaptic defects in flies with mutations in Flower (a protein with no known relation to Spastin) and mobility defects in flies lacking Kat60-L1, another microtubule-severing protein enriched in the CNS. Together, these data support the hypothesis that the beneficial effects of cold extend beyond specific alleviation of Spastin dysfunction, to at least a subset of cellular and behavioral neuronal defects. Mild hypothermia, a common neuroprotective technique in clinical treatment of acute anoxia, might thus hold additional promise as a therapeutic approach for AD-HSP and, potentially, for other neurodegenerative diseases. PMID:24906373

  14. Cold Oxygen Plasma Treatments for the Improvement of the Physicochemical and Biodegradable Properties of Polylactic Acid Films for Food Packaging.

    PubMed

    Song, Ah Young; Oh, Yoon Ah; Roh, Si Hyeon; Kim, Ji Hyeon; Min, Sea C

    2016-01-01

    The effects of cold plasma (CP) treatment on the physicochemical and biodegradable properties of polylactic acid (PLA) films were studied. The PLA films were exposed to CP for 40 min at 900 W and 667 Pa using oxygen as the plasma-forming gas. The tensile, optical, and dynamic mechanical thermal properties, surface morphology, printability, water contact angle, chemical structure, weight change, and biodegradability properties of the films were evaluated during storage for up to 56 d. The tensile and optical properties of the PLA films were not significantly affected by CP treatment (CPT; P > 0.05). The surface roughness and water contact angle of PLA films increased by CPT and further increased during storage for 56 d. The printability of the PLA films increased following CPT and remained stable throughout the storage period. CP-induced hydrophilicity was also sustained during the storage period. The PLA films lost 1.9% of their weight after CPT, but recovered 99.5% of this loss after 14 d in storage. Photodegradation, thermal, and microbial biodegradable properties of the films were significantly improved by CPT (P < 0.05). Accelerated biodegradation of CP-treated PLA sachets with and without cheese was observed in compost. These results demonstrate the potential of CPT for modifying the stiffness, water contact angle, and chemical structure of PLA films and improving the printability and biodegradability of the films for food packaging. PMID:26646616

  15. Some like it hot, some like it cold: Temperature dependent biotechnological applications and improvements in extremophilic enzymes.

    PubMed

    Siddiqui, Khawar Sohail

    2015-12-01

    The full biotechnological exploitation of enzymes is still hampered by their low activity, low stability and high cost. Temperature-dependent catalytic properties of enzymes are a key to efficient and cost-effective translation to commercial applications. Organisms adapted to temperature extremes are a rich source of enzymes with broad ranging thermal properties which, if isolated, characterized and their structure-function-stability relationship elucidated, could underpin a variety of technologies. Enzymes from thermally-adapted organisms such as psychrophiles (low-temperature) and thermophiles (high-temperature) are a vast natural resource that is already under scrutiny for their biotechnological potential. However, psychrophilic and thermophilic enzymes show an activity-stability trade-off that necessitates the use of various genetic and chemical modifications to further improve their properties to suit various industrial applications. This review describes in detail the properties and biotechnological applications of both cold-adapted and thermophilic enzymes. Furthermore, the review critically examines ways to improve their value for biotechnology, concluding by proposing an integrated approach involving thermally-adapted, genetically and magnetically modified enzymes to make biocatalysis more efficient and cost-effective. PMID:26585268

  16. Improving the environment for weaned piglets using polypropylene fabrics above the animals in cold periods

    NASA Astrophysics Data System (ADS)

    Dolz, Noé; Babot, Daniel; Álvarez-Rodríguez, Javier; Forcada, Fernando

    2015-12-01

    This study aimed at evaluating the use of polypropylene fabrics in weaned pig facilities (5-10 weeks of age) during the winter period to improve thermal environment and energy saving for heating. Two experiments were conducted to validate the effects of fabrics (F) compared to control (C) in three 2-week periods using natural ventilation (assay 1, 2013) and forced ventilation (assay 2, 2014). Air temperature was greater in F than in C compartments in both years, particularly during the first 2-week periods (2 °C of mean difference). Natural ventilation was not enough to maintain relative humidity levels below 70 % at the end of the postweaning period (9-10 weeks of age) in both groups (F and C), whereas forced ventilation allowed controlling daily mean relative humidity levels <60 %. About 12-26 % of the radiant heat was transmitted through the fabrics cover, depending on the wavelength. There were no differences on growth performance of piglets in the two compartments in both years. The use of polypropylene fabrics was associated with a significant electric energy saving for heating during the first (data available only in 2014) and second 2-week period in both years. In conclusion, polypropylene fabrics may be an interesting tool to provide optimal environmental conditions for weaned piglets in winter, especially during the two first weeks after weaning. Their transmittance properties allow trapping infrared emission produced by the piglets and heating, avoiding heat losses through the roof, and therefore saving heating energy.

  17. Improving the environment for weaned piglets using polypropylene fabrics above the animals in cold periods.

    PubMed

    Dolz, Noé; Babot, Daniel; Álvarez-Rodríguez, Javier; Forcada, Fernando

    2015-12-01

    This study aimed at evaluating the use of polypropylene fabrics in weaned pig facilities (5-10 weeks of age) during the winter period to improve thermal environment and energy saving for heating. Two experiments were conducted to validate the effects of fabrics (F) compared to control (C) in three 2-week periods using natural ventilation (assay 1, 2013) and forced ventilation (assay 2, 2014). Air temperature was greater in F than in C compartments in both years, particularly during the first 2-week periods (2 °C of mean difference). Natural ventilation was not enough to maintain relative humidity levels below 70 % at the end of the postweaning period (9-10 weeks of age) in both groups (F and C), whereas forced ventilation allowed controlling daily mean relative humidity levels <60 %. About 12-26 % of the radiant heat was transmitted through the fabrics cover, depending on the wavelength. There were no differences on growth performance of piglets in the two compartments in both years. The use of polypropylene fabrics was associated with a significant electric energy saving for heating during the first (data available only in 2014) and second 2-week period in both years. In conclusion, polypropylene fabrics may be an interesting tool to provide optimal environmental conditions for weaned piglets in winter, especially during the two first weeks after weaning. Their transmittance properties allow trapping infrared emission produced by the piglets and heating, avoiding heat losses through the roof, and therefore saving heating energy. PMID:25910465

  18. A deficiency in cold-inducible RNA-binding protein accelerates the inflammation phase and improves wound healing.

    PubMed

    Idrovo, Juan Pablo; Jacob, Asha; Yang, Weng Lang; Wang, Zhimin; Yen, Hao Ting; Nicastro, Jeffrey; Coppa, Gene F; Wang, Ping

    2016-02-01

    Chronic or non-healing wounds are a major concern in clinical practice and these wounds are mostly associated with diabetes, and venous and pressure ulcers. Wound healing is a complex process involving overlapping phases and the primary phase in this complex cascade is the inflammatory state. While inflammation is necessary for wound healing, a prolonged inflammatory phase leads to impaired healing. Cold-inducible RNA-binding protein (CIRP) belongs to a family of cold-shock proteins that are expressed in high levels under stress conditions. Recently, we demonstrated that a deficiency in CIRP led to decreased inflammation and mortality in an experimental model of hemorrhagic shock. Thus, we hypothesized that a deficiency in CIRP would accelerate the inflammatory phase and lead to an improvement in cutaneous wound healing. In this study, to examine this hypothesis, a full-thickness wound was created on the dorsum of wild-type (WT) and CIRP-/- mice. The wound size was measured every other day for 14 days. The wound area was significantly decreased in the CIRP-/- mice by day 9 and continued to decrease until day 14 compared to the WT mice. In a separate cohort, mice were sacrificed on days 3 and 7 after wounding and the skin tissues were harvested for histological analysis and RNA measurements. On day 3, the mRNA expression of tumor necrossis factor (TNF)-α in the skin tissues was increased by 16-fold in the WT mice, whereas these levels were increased by 65-fold in the CIRP-/- mice. Of note on day 7, while the levels of TNF-α remained high in the WT mice, these levels were significantly decreased in the CIRP-/- mice. The histological analysis of the wounded skin tissue indicated an improvement as early as day 3 in the CIRP-/- mice, whereas in the WT mice, infiltrated immune cells were still present on day 7. On day 7 in the CIRP-/- mice, Gr-1 expression was low and CD31 expression was high, whereas in the WT mice, Gr-1 expression was high and CD31 expression was low

  19. Starting Over.

    ERIC Educational Resources Information Center

    Wilson, Laval S.

    1994-01-01

    Following the August 1991 state takeover of the Paterson (New Jersey) Schools, the new district superintendent launched a program to improve the city's four worst elementary schools. The process involved creating an administrative team to evaluate principals and school programs, replacing key staff, forming a partnership with Columbia University's…

  20. Common cold

    MedlinePlus

    ... are the most common reason that children miss school and parents miss work. Parents often get colds ... other children. A cold can spread quickly through schools or daycares. Colds can occur at any time ...

  1. Common Cold

    MedlinePlus

    ... coughing - everyone knows the symptoms of the common cold. It is probably the most common illness. In ... people in the United States suffer 1 billion colds. You can get a cold by touching your ...

  2. Cold Stress

    MedlinePlus

    ... be at risk of cold stress. Extreme cold weather is a dangerous situation that can bring on ... the country. In regions relatively unaccustomed to winter weather, near freezing temperatures are considered factors for cold ...

  3. Cold intolerance

    MedlinePlus

    ... intolerance is an abnormal sensitivity to a cold environment or cold temperatures. ... can be a symptom of a problem with metabolism. Some people (often very thin women) do not tolerate cold environments because they have very little body fat and ...

  4. A cold, slow beam of TlF molecules for an improved probe for the nuclear Schiff moment

    NASA Astrophysics Data System (ADS)

    McCarron, Daniel; Edwards, Eustace; Steinecker, Matthew; Peck, Stephen; Hunter, Larry; Demille, David

    2016-05-01

    We present a new experimental effort to search for the nuclear Schiff moment (SM) using thallium fluoride (TlF) molecules. Our approach capitalizes on the strong internal electric field present in a polarized molecule to amplify the effect of the SM. We project a 25-fold improvement over the current state of the art sensitivity to certain underlying mechanisms such as the CP-violating QCD θ-parameter. Our recent measurements indicate that optical cycling is possible on the X1Σ+ -->B3Π1 electronic transition of TlF. Here a single laser will enable 100 photons to be scattered before an excited vibrational level is populated. This is sufficient for unit-efficiency fluorescence detection, rotational cooling, and state preparation. With a single repump laser, ~ 104 photons could be scattered, sufficient for transverse laser cooling that could substantially increase the brightness of the molecular beam. We report on the production of a cold and slow beam of TlF molecules from a cryogenic buffer gas beam source and present flux measurements for a range of TlF vaporization techniques. We also present our progress towards understanding the hyperfine structure in the B3Π1 state and its role in optical cycling.

  5. A consortium of rhizobacterial strains and biochemical growth elicitors improve cold and drought stress tolerance in rice (Oryza sativa L.).

    PubMed

    Kakar, K U; Ren, X-L; Nawaz, Z; Cui, Z-Q; Li, B; Xie, G-L; Hassan, M A; Ali, E; Sun, G-C

    2016-05-01

    In the present study, a consortium of two rhizobacteria Bacillus amyloliquefaciens Bk7 and Brevibacillus laterosporus B4, termed 'BB', biochemical elicitors salicylic acid and β-aminobutyric acid (SB) and their mixture (BBSB) were investigated for cold and drought stress tolerance in rice plants. After withholding water for 16 days, rice plants treated with BBSB showed 100% survival, improved seedling height (35.4 cm), shoot number (6.12), and showed minimum symptoms of chlorosis (19%), wilting (4%), necrosis (6%) and rolling of leaves. Similarly, BB inoculation enhanced plant growth and reduced overall symptoms in rice seedlings subjected to 0 ± 5 °C for 24 h. Our results imply several mechanisms underlying BB- and BBSB-elicited stress tolerance. In contrast to the control, both treatments significantly decreased leaf monodehydroascorbate (MDA) content and electrolyte leakage, and increased leaf proline and cholorophyll content. Moreover, activities of antioxidant enzymes, superoxide dismutase (SOD) and catalase (CAT) increased 3.0- and 3.6-fold, respectively. Moreover, expression of OsMYB3R-2, OsDIL, OsDREB1A and OsCDPK13 genes was significantly up-regulated, suggesting that these genes play important roles in abiotic stress tolerance of rice. In addition, bacterial strains Bk7 and B4 were able to produce high amounts of IAA and siderophores, and colonise the plant roots, while only strain Bk7 exhibited the capability to form biofilms and solubilise inorganic phosphate. This study indicates that the BB and BBSB bio-formulations can be used to confer induced systematic tolerance and improve the health of rice plants subject to chilling and drought stress. PMID:26681628

  6. Maryland Early Head Start Initiative

    ERIC Educational Resources Information Center

    Center for Law and Social Policy, Inc. (CLASP), 2012

    2012-01-01

    Since 2000, Maryland has provided state supplemental funds to Head Start and Early Head Start (EHS) programs to improve access. Local EHS programs may use funds, through child care partnerships, to extend the EHS day or year. Maryland's approach to building on EHS includes: (1) Increase the capacity of existing Head Start and EHS programs to…

  7. Head Start: An Effective Program But the Fund Distribution Formula Needs Revision and Management Controls Need Improvement. Report to the Congress of the United States by the Comptroller General.

    ERIC Educational Resources Information Center

    Comptroller General of the U.S., Washington, DC.

    This report from the Comptroller General to the United States Congress finds Head Start to be an effective program whose fund distribution formula needs revision and whose management controls need improvement. Head Start's funding for enrollment and operating costs increased significantly between 1977-81. However, these funding increases were not…

  8. Improving the health forecasting alert system for cold weather and heat-waves in England: a case-study approach using temperature-mortality relationships

    NASA Astrophysics Data System (ADS)

    Masato, Giacomo; Cavany, Sean; Charlton-Perez, Andrew; Dacre, Helen; Bone, Angie; Carmicheal, Katie; Murray, Virginia; Danker, Rutger; Neal, Rob; Sarran, Christophe

    2015-04-01

    The health forecasting alert system for cold weather and heatwaves currently in use in the Cold Weather and Heatwave plans for England is based on 5 alert levels, with levels 2 and 3 dependent on a forecast or actual single temperature action trigger. Epidemiological evidence indicates that for both heat and cold, the impact on human health is gradual, with worsening impact for more extreme temperatures. The 60% risk of heat and cold forecasts used by the alerts is a rather crude probabilistic measure, which could be substantially improved thanks to the state-of-the-art forecast techniques. In this study a prototype of a new health forecasting alert system is developed, which is aligned to the approach used in the Met Office's (MO) National Severe Weather Warning Service (NSWWS). This is in order to improve information available to responders in the health and social care system by linking temperatures more directly to risks of mortality, and developing a system more coherent with other weather alerts. The prototype is compared to the current system in the Cold Weather and Heatwave plans via a case-study approach to verify its potential advantages and shortcomings. The prototype health forecasting alert system introduces an "impact vs likelihood matrix" for the health impacts of hot and cold temperatures which is similar to those used operationally for other weather hazards as part of the NSWWS. The impact axis of this matrix is based on existing epidemiological evidence, which shows an increasing relative risk of death at extremes of outdoor temperature beyond a threshold which can be identified epidemiologically. The likelihood axis is based on a probability measure associated with the temperature forecast. The new method is tested for two case studies (one during summer 2013, one during winter 2013), and compared to the performance of the current alert system. The prototype shows some clear improvements over the current alert system. It allows for a much greater

  9. Integration of selective breeding and vaccination to improve disease resistance in aquaculture: Application to control bacterial cold water disease

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Bacterial cold water disease (BCWD) is a frequent cause of elevated mortality in rainbow trout and the development of effective control strategies is a priority within the U.S. A goal of the NCCCWA breeding program is to produce germplasm with superior growth and survival following exposure to infe...

  10. Ultraviolet-B radiation induced crosslinking improves physical properties of cold- and warm-water fish gelatin gels and films

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Cold- and warm-water fish gelatin granules were exposed to ultraviolet-B radiation for doses up to 29.7 J/cm2. Solutions and films were prepared from the granules. Gel electrophoresis and refractive index were used to examine changes in molecular weight of the samples. Also, the gel strength and rhe...

  11. Common Cold

    MedlinePlus

    ... News & Events Volunteer NIAID > Health & Research Topics > Common Cold Skip Website Tools Website Tools Print this page ... Help people who are suffering from the common cold by volunteering for NIAID clinical studies on ClinicalTrials. ...

  12. Improvement of flavor and viscosity in hot and cold break tomato juice and sauce by peel removal.

    PubMed

    Mirondo, Rita; Barringer, Sheryl

    2015-01-01

    Tomatoes are typically not peeled before being made into juice but the peels contain enzymes that affect the odor, flavor, and viscosity of the juice. The peels are removed in the finisher, but their presence during the break process may affect quality. Juice was processed from peeled and unpeeled tomatoes using hot or cold break. The juices were pasteurized by high temperature short time (HTST), low temperature long time (LTLT), or with a retort. The control samples were treated with 10% calcium chloride to stop enzymatic activity in the juice. Sauce was made from juice and the tomato products were analyzed for volatiles, color, viscosity, and by sensory. Cold break juice made with peel contained higher levels of some lipoxygenase-, carotenoid-, and amino acid-derived volatiles, than the juice made without peel. Because of the lack of enzyme activity, hot break juices had lower levels of these volatiles and there was no significant difference between hot break juices made with and without peel. CaCl2 -treated and HTST juice had higher levels of most of the volatiles than LTLT, including the lipoxygenase-derived volatiles. The presence of peel produced a significant decrease in the viscosity of the cold break juice and sauce. There was no significant difference in the hue angle, total soluble solids, pH, titratable acidity, and vitamin C for most of the treatments. The texture, flavor, and overall liking of cold break juice made without peel were preferred over cold break juice made with peel whereas the color was less preferred. Between the sauces no significant differences in preference were obtained. PMID:25603846

  13. Taking the START II debate to Moscow

    SciTech Connect

    1996-10-01

    The author explains why the START II Treaty should be ratified and implemented. When the START I reductions are completed, the United States, and Russia will each have about 6,000 strategic nuclear warheads. Additionally, there are thousands of nuclear warheads in our tactical forces, with thousands more in secure storage areas. And there are thousands of kilograms of weapons-grade uranium and plutonium in storage, with nuclear reactors making still more. This huge infrastructure requires a considerable expense to maintain, and it requires stringent safety and security measures. The security features are particularly important since a handful of rogue nations are trying to get their hands on our nuclear weapons or the plutonium which would allow them to make their own. Additionally, terrorist groups are seeking to obtain nuclear weapons or assorted radioactive material. Therefore, it is in the supreme interest of Russia and the United States, the two great nuclear powers, to lead the world in controlling these terrible weapons and the deadly plutonium from which they are made. Key to this control is making the dramatic reductions in the deadly legacy of the Cold War-the nuclear infrastructure: warheads, missiles, weapons-grade uranium and plutonium, launch facilities, and manufacturing facilities. We initiated reductions in 1991 with the START I treaty, which reduces nuclear warheads by half-Russia and the United States are both well ahead of schedule in making the reductions called for in START I. We followed that in 1994 with the Trilateral Agreement to transfer nuclear weapons from Ukraine to Russia. Today, Ukraine and Kazakhstan are nuclear-weapons free. The next major step is START II, which will result in another reduction in nuclear warheads by half. Both Russia and the United States have far too many nuclear weapons and we can both improve our security and our safety by making dramatic reductions.

  14. Nebraska: Early Head Start Initiative

    ERIC Educational Resources Information Center

    Center for Law and Social Policy, Inc. (CLASP), 2012

    2012-01-01

    Since 1999, Nebraska's Early Head Start Infant/Toddler Quality Initiative has supported Early Head Start (EHS) and community child care partnerships to improve the quality and professionalism of infant and toddler care. EHS programs apply to receive funding to establish partnerships with center-based or home-based child care.The initiative has…

  15. The Starting Early Starting Smart Story.

    ERIC Educational Resources Information Center

    Casey Family Programs, Seattle, WA.

    Starting Early Starting Smart (SESS) is an early childhood public/private initiative designed to identify new, empirical knowledge about the effectiveness of integrating substance abuse prevention, addictions treatment, and mental health services with primary health care and childcare service settings (e.g., Head Start, day care, preschool) to…

  16. Assessing and improving health in the workplace: an integration of subjective and objective measures with the STress Assessment and Research Toolkit (St.A.R.T.) method

    PubMed Central

    2012-01-01

    Background The aim of this work was to introduce a new combined method of subjective and objective measures to assess psychosocial risk factors at work and improve workers’ health and well-being. In the literature most of the research on work-related stress focuses on self-report measures and this work represents the first methodology capable of integrating different sources of data. Method An integrated method entitled St.A.R.T. (STress Assessment and Research Toolkit) was used in order to assess psychosocial risk factors and two health outcomes. In particular, a self-report questionnaire combined with an observational structured checklist was administered to 113 workers from an Italian retail company. Results The data showed a correlation between subjective data and the rating data of the observational checklist for the psychosocial risk factors related to work contexts such as customer relationship management and customer queue. Conversely, the factors related to work content (workload and boredom) measured with different methods (subjective vs. objective) showed a discrepancy. Furthermore, subjective measures of psychosocial risk factors were more predictive of workers’ psychological health and exhaustion than rating data. The different objective measures played different roles, however, in terms of their influence on the two health outcomes considered. Conclusions It is important to integrate self-related assessment of stressors with objective measures for a better understanding of workers’ conditions in the workplace. The method presented could be considered a useful methodology for combining the two measures and differentiating the impact of different psychological risk factors related to work content and context on workers’ health. PMID:22995286

  17. Improvement of COBRA-TF for modeling of PWR cold- and hot-legs during reactor transients

    NASA Astrophysics Data System (ADS)

    Salko, Robert K.

    COBRA-TF is a two-phase, three-field (liquid, vapor, droplets) thermal-hydraulic modeling tool that has been developed by the Pacific Northwest Laboratory under sponsorship of the NRC. The code was developed for Light Water Reactor analysis starting in the 1980s; however, its development has continued to this current time. COBRA-TF still finds wide-spread use throughout the nuclear engineering field, including nuclear-power vendors, academia, and research institutions. It has been proposed that extension of the COBRA-TF code-modeling region from vessel-only components to Pressurized Water Reactor (PWR) coolant-line regions can lead to improved Loss-of-Coolant Accident (LOCA) analysis. Improved modeling is anticipated due to COBRA-TF's capability to independently model the entrained-droplet flow-field behavior, which has been observed to impact delivery to the core region[1]. Because COBRA-TF was originally developed for vertically-dominated, in-vessel, sub-channel flow, extension of the COBRA-TF modeling region to the horizontal-pipe geometries of the coolant-lines required several code modifications, including: • Inclusion of the stratified flow regime into the COBRA-TF flow regime map, along with associated interfacial drag, wall drag and interfacial heat transfer correlations, • Inclusion of a horizontal-stratification force between adjacent mesh cells having unequal levels of stratified flow, and • Generation of a new code-input interface for the modeling of coolant-lines. The sheer number of COBRA-TF modifications that were required to complete this work turned this project into a code-development project as much as it was a study of thermal-hydraulics in reactor coolant-lines. The means for achieving these tasks shifted along the way, ultimately leading the development of a separate, nearly completely independent one-dimensional, two-phase-flow modeling code geared toward reactor coolant-line analysis. This developed code has been named CLAP, for

  18. Improvement of COBRA-TF for modeling of PWR cold- and hot-legs during reactor transients

    NASA Astrophysics Data System (ADS)

    Salko, Robert K.

    COBRA-TF is a two-phase, three-field (liquid, vapor, droplets) thermal-hydraulic modeling tool that has been developed by the Pacific Northwest Laboratory under sponsorship of the NRC. The code was developed for Light Water Reactor analysis starting in the 1980s; however, its development has continued to this current time. COBRA-TF still finds wide-spread use throughout the nuclear engineering field, including nuclear-power vendors, academia, and research institutions. It has been proposed that extension of the COBRA-TF code-modeling region from vessel-only components to Pressurized Water Reactor (PWR) coolant-line regions can lead to improved Loss-of-Coolant Accident (LOCA) analysis. Improved modeling is anticipated due to COBRA-TF's capability to independently model the entrained-droplet flow-field behavior, which has been observed to impact delivery to the core region[1]. Because COBRA-TF was originally developed for vertically-dominated, in-vessel, sub-channel flow, extension of the COBRA-TF modeling region to the horizontal-pipe geometries of the coolant-lines required several code modifications, including: • Inclusion of the stratified flow regime into the COBRA-TF flow regime map, along with associated interfacial drag, wall drag and interfacial heat transfer correlations, • Inclusion of a horizontal-stratification force between adjacent mesh cells having unequal levels of stratified flow, and • Generation of a new code-input interface for the modeling of coolant-lines. The sheer number of COBRA-TF modifications that were required to complete this work turned this project into a code-development project as much as it was a study of thermal-hydraulics in reactor coolant-lines. The means for achieving these tasks shifted along the way, ultimately leading the development of a separate, nearly completely independent one-dimensional, two-phase-flow modeling code geared toward reactor coolant-line analysis. This developed code has been named CLAP, for

  19. Chronic Mild Cold Conditioning Modulates the Expression of Hypothalamic Neuropeptide and Intermediary Metabolic-Related Genes and Improves Growth Performances in Young Chicks

    PubMed Central

    Nguyen, Phuong; Greene, Elizabeth; Ishola, Peter; Huff, Geraldine; Donoghue, Annie; Bottje, Walter; Dridi, Sami

    2015-01-01

    Background Low environmental temperatures are among the most challenging stressors in poultry industries. Although landmark studies using acute severe cold exposure have been conducted, still the molecular mechanisms underlying cold-stress responses in birds are not completely defined. In the present study we determine the effect of chronic mild cold conditioning (CMCC) on growth performances and on the expression of key metabolic-related genes in three metabolically important tissues: brain (main site for feed intake control), liver (main site for lipogenesis) and muscle (main site for thermogenesis). Methods 80 one-day old male broiler chicks were divided into two weight-matched groups and maintained in two different temperature floor pen rooms (40 birds/room). The temperature of control room was 32°C, while the cold room temperature started at 26.7°C and gradually reduced every day (1°C/day) to reach 19.7°C at the seventh day of the experiment. At day 7, growth performances were recorded (from all birds) and blood samples and tissues were collected (n = 10). The rest of birds were maintained at the same standard environmental condition for two more weeks and growth performances were measured. Results Although feed intake remained unchanged, body weight gain was significantly increased in CMCC compared to the control chicks resulting in a significant low feed conversion ratio (FCR). Circulating cholesterol and creatine kinase levels were higher in CMCC chicks compared to the control group (P<0.05). CMCC significantly decreased the expression of both the hypothalamic orexigenic neuropeptide Y (NPY) and anorexigenic cocaine and amphetamine regulated transcript (CART) in chick brain which may explain the similar feed intake between the two groups. Compared to the control condition, CMCC increased the mRNA abundance of AMPKα1/α2 and decreased mTOR gene expression (P<0.05), the master energy and nutrient sensors, respectively. It also significantly decreased the

  20. Cold Atoms

    NASA Astrophysics Data System (ADS)

    Bellac, Michel Le

    2014-11-01

    This chapter and the following one address collective effects of quantum particles, that is, the effects which are observed when we put together a large number of identical particles, for example, electrons, helium-4 or rubidium-85 atoms. We shall see that quantum particles can be classified into two categories, bosons and fermions, whose collective behavior is radically different. Bosons have a tendency to pile up in the same quantum state, while fermions have a tendency to avoid each other. We say that bosons and fermions obey two different quantum statistics, the Bose-Einstein and the Fermi-Dirac statistics, respectively. Temperature is a collective effect, and in Section 5.1 we shall explain the concept of absolute temperature and its relation to the average kinetic energy of molecules. We shall describe in Section 5.2 how we can cool atoms down thanks to the Doppler effect, and explain how cold atoms can be used to improve the accuracy of atomic clocks by a factor of about 100. The effects of quantum statistics are prominent at low temperatures, and atom cooling will be used to obtain Bose-Einstein condensates at low enough temperatures, when the atoms are bosons.

  1. A pilot study of a pictorial bilingual nutrition education game to improve the consumption of healthful foods in a head start population.

    PubMed

    Piziak, Veronica

    2012-04-01

    The prevalence of early childhood obesity has increased dramatically particularly among the Mexican American population. Obesity leads to earlier onset of related diseases such as type 2 diabetes. The Head Start population of Texas is largely Mexican American. Dietary intake in this population demonstrated a diet very low in fiber, high in salt, and containing excessive calories with a low intake of fruit and vegetables. This study was performed in a Texas Head Start population to evaluate a bilingual pictorial nutrition education game. Acceptance of the bilingual concept and the game had been previously studied in a Head Start population in five Texas counties. The effectiveness in producing a change in eating habits was studied as a pilot project 413 children and their parents at the Bastrop County Head Start. Parents were asked to supply data about at home food frequency at the beginning and the end of the school year and the results compared. The parents were given a demonstration of the educational objectives and the students played the game throughout the year. By the end of the school year there was a statistically significant increase in the vegetables offered to this population both during the week at home (p = 0.009) and on the weekends (p = 0.02). PMID:22690195

  2. Head Start: A More Comprehensive Risk Management Strategy and Data Improvements Could Further Strengthen Program Oversight. Report to Congressional Requesters. GAO-08-221

    ERIC Educational Resources Information Center

    Government Accountability Office, 2008

    2008-01-01

    In February 2005, the U.S. Government Accountability Office (GAO) issued a report that raised concerns about the effectiveness of the Department of Health and Human Services (HHS) Administration for Children and Families' (ACF) oversight of about 1,600 local organizations that receive nearly $7 billion in Head Start grants. GAO was asked to report…

  3. Rapid isolation, reliable characterization, and water solubility improvement of polymethoxyflavones from cold-pressed mandarin essential oil.

    PubMed

    Russo, Marina; Rigano, Francesca; Arigò, Adriana; Sciarrone, Danilo; Calabrò, Maria Luisa; Farnetti, Sara; Dugo, Paola; Mondello, Luigi

    2016-06-01

    Polymethoxyflavones possess many biological properties, as lipid-lowering, hypoglycaemic, anti-inflammatory, antioxidant, and anticancer activities, therefore, they may be employed as nutraceuticals or therapeutic agents. The scarcity of pure polymethoxyflavones on the market as well as their low water solubility limited in vivo studies and the use of polymethoxyflavones as food or pharmaceutical supplements. Since mandarin peels are a rich source of polymethoxyflavones, tangeretin, nobiletin, sinensetin, tetra-O-methyl scutellarein, and heptamethoxyflavone were purified from a nonvolatile residue of a cold-pressed mandarin essential oil using a multidimensional preparative liquid chromatographic system coupled with a photodiode array detector and a single quadrupole mass spectrometer. A new prototype, consisting of a nano-liquid chromatography system coupled with an electron ionization mass spectrometer, was used for the characterization of the pure isolated molecules. Finally, due to the collection of highly pure nobiletin and tangeretin, the ability of 2-hydroxypropyl-β-cyclodextrin to enhance the water solubility of both polymethoxyflavones was evaluated by phase solubility studies and Job's plot method. PMID:27060470

  4. Cholesterol-Loaded Cyclodextrin Increases the Cholesterol Content of Goat Sperm to Improve Cold and Osmotic Resistance and Maintain Sperm Function after Cryopreservation.

    PubMed

    Salmon, Vianney M; Leclerc, Pierre; Bailey, Janice L

    2016-04-01

    The success of semen cryopreservation depends on sperm membrane integrity and function after thawing. Cholesterol-loaded cyclodextrin (CLC) is used for in vitro incorporation of cholesterol to protect cells against cold temperatures. We hypothesized that CLC treatment also enhances sperm cholesterol content to increase tolerance to osmotic shock and cryoresistance, thereby improving fertility. We confirmed the fact that treatment of goat semen with 3 mg/ml CLC increases sperm cholesterol content using both the Liebermann-Burchard approach and filipin III labeling of membrane cholesterol. Sperm were then treated with or without CLC and cryopreserved. After thawing, sperm cholesterol dramatically fell, even in the presence of CLC, which explains the mechanism of cryocapacitation. CLC treatment, however, maintained a normal prefreeze cholesterol level in sperm after cryopreservation. Furthermore, fresh sperm treated with CLC and subjected to either cold shock or incubated in hypo-, iso-, and hyperosmotic media, designed to mimic stresses associated with freezing/thawing, displayed increased temperature and osmotic tolerance. CLC treatment also improved sperm viability, motility, and acrosome integrity after thawing. Furthermore, CLC treatment did not affect the sperm's ability to undergo in vitro capacitation according to chlortetracycline fluorescence and protein tyrosine phosphorylation. A pilot field trial demonstrated that artificial insemination with sperm that underwent increased cholesterol levels following CLC treatment yielded higher fertility ( ITALIC! P< 0.1) and proliferation ( ITALIC! P< 0.05) rates in vivo than untreated semen from the same ejaculate samples. These observations suggest that CLC treatment could be used to improve cryoprotection during the freezing and thawing of goat sperm. PMID:26888968

  5. START High Performance Discharges

    NASA Astrophysics Data System (ADS)

    Gates, D. A.

    1997-11-01

    Improvements to START (Small Tight Aspect Ratio Tokamak), the first spherical tokamak in the world to achieve high plasma temperature with both a significant pulse length and confinement time, have been ongoing since 1991. Recent modifications include: expansion of the existing capacitor banks allowing plasma currents as high as 300kA, an increase in the available neutral beam heating power ( ~ 500kW), and improvements to the vacuum system. These improvements have led to the achievement of the world record plasma β (≡ 2μ_0 /B^2) of ~ 30% in a tokamak. The normalised β ( βN ≡ β aB/I_p) reached 4.5 with q_95 = 2.3. Properties of the reconstructed equilibrium will be discussed in detail. The theoretical limit to β is higher in a spherical tokamak than in a conventional machine, due to the higher values of normalised current (IN ≡ I_p/aB) achievable at low aspect ratio. The record β was achieved with IN ~ 8 while conventional tokamaks are limited to IN ~ 3, or less. Calculations of the ideal MHD stability of the record discharge indicate high β low-n kink modes are stable, but that the entire profile is at or near marginal stability for high-n ballooning modes. The phenomenology of the events leading up to the plasma termination is discussed. An important aspect of the START program is to explore the physics of neutral beam absorption at low aspect ratio. A passive neutral particle analyser has been used to study the temporal and spatial dependence of the fast hydrogen beam ions. These measurements have been used in conjunction with a single particle orbit code to estimate the fast ion losses due to collisions with slow neutrals from the plasma edge. Numerical analysis of neutral beam power deposition profiles are compared with the data from an instrumented beam stop. The global energy confinement time τE in beam heated discharges on START is similar to that obtained in Ohmic discharges, even though the input power has roughly doubled over the Ohmic case

  6. Common cold

    MedlinePlus

    ... often causes a runny nose, nasal congestion, and sneezing. You may also have a sore throat, cough, ... symptoms are: Nasal congestion Runny nose Scratchy throat Sneezing Adults and older children with colds generally have ...

  7. Cold Intolerance

    MedlinePlus

    ... from the Handbook on the Late Effects of Poliomyelitis for Physicians and Survivors © Cold Intolerance Many polio ... index of Handbook on the Late Effects of Poliomyelitis for Physicians and Survivors © Back to top Contact ...

  8. Cold plasma ashing improves the trace element detection of single Daphnia specimens by total reflection X-ray fluorescence spectrometry

    NASA Astrophysics Data System (ADS)

    Woelfl, Stefan; Mages, Margarete; Encina, Francisco

    2003-12-01

    The recently developed dry method for the element determination of single freshwater microcrustacean specimens ( Daphnia) using total reflection X-ray fluorescence (TXRF) spectrometry showed that inhomogeneities of the biological material on the glass carriers resulted in some cases in high background and hampered the detection of certain trace elements (e.g. Cr, Ni). The aim of this study was to test how inhomogeneities of the biological material can be reduced using cold plasma ashing (CPA) techniques. For that, single specimens of the microcrustacean Daphnia pulex prepared according to the dry method were measured by TXRF before and after CPA. To determine the efficiency of the removal of organic matrix, the background and signal-to-background relationship of 28 samples were analyzed. The results showed (1) a highly significant reduction of the background by CPA fluctuating between 26 and 46% (all elements) and (2) a significant increase of the signal-to-background relationship by the factor 1.5-2.5 (all elements) and a much better detection of Cr, Pb, As and Se. The element concentrations (with exception of Cr, Ni and Pb) after ashing were in the same range or slightly higher than that before ashing. No significant differences between the two treatments were observed for Mn, As, Pb, Se (November), Sr (November), Cr (March) and Pb (March). The element concentration of P, K, Ca, Cu, Zn, Cr (November), Fe and Rb were significantly higher after ashing. In general, they increased by 1.5-13.6% and were highest for Rb (March) and P (November). In contrast, the element concentration of Ni and Cr (only March) decreased significantly after ashing (Ni: 91.6-92.1%, Cr: 91.3%). We recommend the use of CPA for biological material in the microgram-range as a routine method for TXRF analysis, especially when trace elements in minute concentrations are of interest.

  9. Hyaluronic Acid (800 kDa) Supplementation of University of Wisconsin Solution Improves Viability of Osteochondral Grafts and Reduces Matrix Metalloproteinase Expression during Cold Preservation

    PubMed Central

    Yamada, Takuya; Uchida, Kentaro; Onuma, Kenji; Inoue, Gen; Aikawa, Jun; Takano, Shotaro; Sekiguchi, Hiroyuki; Fujimaki, Hisako; Miyagi, Masayuki; Takaso, Masashi

    2015-01-01

    Osteochondral allografting is a promising option for the treatment of large cartilage defects. However, because the cell viability of osteochondral tissues (OCTs) gradually reduces during storage at 4°C, methods for maintaining the cell viability of fresh OCTs are needed to improve transplantation outcomes. Here, we evaluated whether the supplementation of preservation solution with one of three different molecular weight forms of hyaluronic acid (HA) improved the viability of rat OCTs during long-term cold storage. The supplementation of University of Wisconsin (UW) solution with 800 kDa significantly improved the cell viability of OCT after 14 days at 4°C compared to nonsupplemented UW solution. In contrast, UW solution supplemented with either 1900 or 6000 kDa HA did not markedly improve the cell viability of the OCT. Real-time PCR analysis revealed that the levels of matrix metalloproteinases 2, 3, and 9 were significantly decreased in OCT stored in UW solution supplemented with 800 kDa HA. Although further studies in human OCT are warranted, these findings demonstrate that the use of 800 kDa HA in place of serum may be a suitable approach for the long-term preservation of osteochondral allografts designated for the repair of large cartilage defects in the clinical setting. PMID:26199955

  10. Cold energy

    NASA Astrophysics Data System (ADS)

    Wallace, John P.

    2015-12-01

    Deviations in Q for resonant superconducting radio frequency niobium accelerator cavities are generally correlated with resistivity loss mechanisms. Field dependent Qs are not well modeled by these classical loss mechanisms, but rather can represent a form of precision cavity surface thermometry. When the field dependent Q variation shows improvement with increasing B field level the classical treatment of this problem is inadequate. To justify this behavior hydrogen as a ubiquitous impurity in niobium, which creates measurable property changes, even at very low concentrations is typically considered the cause of such anomalous behavior. This maybe the case in some instances, but more importantly any system operating with a highly coherent field with a significant time dependent magnetic component at near 2° K will have the ability to organize the remaining free spins within the London penetration depth to form a coupled energy reservoir in the form of low mass spin waves. The niobium resonant cavities are composed of a single isotope with a large nuclear spin. When the other loss mechanisms are stripped away this may be the gain medium activated by the low level residual magnetic fields. It was found that one resonant cavity heat treatment produced optimum surface properties and then functioned as a MASER extracting energy from the 2° K thermal bath while cooling the cavity walls. The cavity operating in this mode is a simulator of what can take place in the wider but not colder universe using the cosmic microwave background (CMB) as a thermal source. The low mass, long lifetimes, and the scale of the magnetic spin waves on the weakly magnetized interstellar medium allows energy to be stored that is many orders of magnitude colder than the cosmic microwave background. A linear accelerator cavity becomes a tool to explore the properties of the long wave length magnetic spin waves that populate this cold low energy regime.

  11. Cold energy

    SciTech Connect

    Wallace, John P.

    2015-12-04

    Deviations in Q for resonant superconducting radio frequency niobium accelerator cavities are generally correlated with resistivity loss mechanisms. Field dependent Qs are not well modeled by these classical loss mechanisms, but rather can represent a form of precision cavity surface thermometry. When the field dependent Q variation shows improvement with increasing B field level the classical treatment of this problem is inadequate. To justify this behavior hydrogen as a ubiquitous impurity in niobium, which creates measurable property changes, even at very low concentrations is typically considered the cause of such anomalous behavior. This maybe the case in some instances, but more importantly any system operating with a highly coherent field with a significant time dependent magnetic component at near 2° K will have the ability to organize the remaining free spins within the London penetration depth to form a coupled energy reservoir in the form of low mass spin waves. The niobium resonant cavities are composed of a single isotope with a large nuclear spin. When the other loss mechanisms are stripped away this may be the gain medium activated by the low level residual magnetic fields. It was found that one resonant cavity heat treatment produced optimum surface properties and then functioned as a MASER extracting energy from the 2° K thermal bath while cooling the cavity walls. The cavity operating in this mode is a simulator of what can take place in the wider but not colder universe using the cosmic microwave background (CMB) as a thermal source. The low mass, long lifetimes, and the scale of the magnetic spin waves on the weakly magnetized interstellar medium allows energy to be stored that is many orders of magnitude colder than the cosmic microwave background. A linear accelerator cavity becomes a tool to explore the properties of the long wave length magnetic spin waves that populate this cold low energy regime.

  12. Improving the Health Forecasting Alert System for Cold Weather and Heat-Waves In England: A Proof-of-Concept Using Temperature-Mortality Relationships

    PubMed Central

    Masato, Giacomo; Bone, Angie; Charlton-Perez, Andrew; Cavany, Sean; Neal, Robert; Dankers, Rutger; Dacre, Helen; Carmichael, Katie; Murray, Virginia

    2015-01-01

    Objectives In this study a prototype of a new health forecasting alert system is developed, which is aligned to the approach used in the Met Office’s (MO) National Severe Weather Warning Service (NSWWS). This is in order to improve information available to responders in the health and social care system by linking temperatures more directly to risks of mortality, and developing a system more coherent with other weather alerts. The prototype is compared to the current system in the Cold Weather and Heatwave plans via a case-study approach to verify its potential advantages and shortcomings. Method The prototype health forecasting alert system introduces an “impact vs likelihood matrix” for the health impacts of hot and cold temperatures which is similar to those used operationally for other weather hazards as part of the NSWWS. The impact axis of this matrix is based on existing epidemiological evidence, which shows an increasing relative risk of death at extremes of outdoor temperature beyond a threshold which can be identified epidemiologically. The likelihood axis is based on a probability measure associated with the temperature forecast. The new method is tested for two case studies (one during summer 2013, one during winter 2013), and compared to the performance of the current alert system. Conclusions The prototype shows some clear improvements over the current alert system. It allows for a much greater degree of flexibility, provides more detailed regional information about the health risks associated with periods of extreme temperatures, and is more coherent with other weather alerts which may make it easier for front line responders to use. It will require validation and engagement with stakeholders before it can be considered for use. PMID:26431427

  13. Cold injuries.

    PubMed

    Long, William B; Edlich, Richard F; Winters, Kathryne L; Britt, L D

    2005-01-01

    Exposure to cold can produce a variety of injuries that occur as a result of man's inability to adapt to cold. These injuries can be divided into localized injury to a body part, systemic hypothermia, or a combination of both. Body temperature may fall as a result of heat loss by radiation, evaporation, conduction, and convection. Hypothermia or systemic cold injury occurs when the core body temperature has decreased to 35 degrees C (95 degrees F) or less. The causes of hypothermia are either primary or secondary. Primary, or accidental, hypothermia occurs in healthy individuals inadequately clothed and exposed to severe cooling. In secondary hypothermia, another illness predisposes the individual to accidental hypothermia. Hypothermia affects multiple organs with symptoms of hypothermia that vary according to the severity of cold injury. The diagnosis of hypothermia is easy if the patient is a mountaineer who is stranded in cold weather. However, it may be more difficult in an elderly patient who has been exposed to a cold environment. In either case, the rectal temperature should be checked with a low-reading thermometer. The general principals of prehospital management are to (1) prevent further heat loss, (2) rewarm the body core temperature in advance of the shell, and (3) avoid precipitating ventricular fibrillation. There are two general techniques of rewarming--passive and active. The mechanisms of peripheral cold injury can be divided into phenomena that affect cells and extracellular fluids (direct effects) and those that disrupt the function of the organized tissue and the integrity of the circulation (indirect effects). Generally, no serious damage is seen until tissue freezing occurs. The mildest form of peripheral cold injury is frostnip. Chilblains represent a more severe form of cold injury than frostnip and occur after exposure to nonfreezing temperatures and damp conditions. Immersion (trench) foot, a disease of the sympathetic nerves and blood

  14. Head Start Facilities Manual.

    ERIC Educational Resources Information Center

    Research Assessment Management, Inc., Silver Spring, MD.

    A quality Head Start facility should provide a physical environment responsive both to the needs of the children and families served and to the needs of staff, volunteers, and community agencies that share space with Head Start. This manual is a tool for Head Start grantees and delegate agencies for assessing existing facilities, making…

  15. The Head Start Debates

    ERIC Educational Resources Information Center

    Zigler, Edward, Ed.; Styfco, Sally J., Ed.

    2004-01-01

    The future of Head Start depends on how well people learn from and apply the lessons from its past. That's why everyone involved in early education needs this timely, forward-thinking book from the leader of Head Start. The first book to capture the Head Start debates in all their complexity and diversity, this landmark volume brings together the…

  16. Parent-delivered compensatory education for children at risk of educational failure: Improving the academic and self-regulatory skills of a Sure Start preschool sample.

    PubMed

    Ford, Ruth M; McDougall, Sine J P; Evans, Daphne

    2009-11-01

    Thirty preschoolers from low-income families participated in a 12-month intervention programme, funded by Sure Start, which engaged them in scaffolded educational activities delivered at home by their mothers. Immediately following the programme, the intervention group outperformed matched controls in tests of academic knowledge, receptive vocabulary, and inhibitory control, but not short-term memory or theory of mind. Teachers' ratings of children's capabilities upon school entry favoured the intervention group, especially in terms of listening, responding, writing, mathematics, and personal/social skills. Superior inhibitory control, short-term memory, and numerical skills were associated with higher ratings whereas theory of mind made a unique, negative contribution to responding. We discuss the implications of these findings for efforts to nurture the development of cognitive self-regulation and school readiness during early childhood. PMID:19261208

  17. Cold Atmospheric Plasma (CAP) Changes Gene Expression of Key Molecules of the Wound Healing Machinery and Improves Wound Healing In Vitro and In Vivo

    PubMed Central

    Arndt, Stephanie; Unger, Petra; Wacker, Eva; Shimizu, Tetsuji; Heinlin, Julia; Li, Yang-Fang; Thomas, Hubertus M.; Morfill, Gregor E.; Zimmermann, Julia L.

    2013-01-01

    Cold atmospheric plasma (CAP) has the potential to interact with tissue or cells leading to fast, painless and efficient disinfection and furthermore has positive effects on wound healing and tissue regeneration. For clinical implementation it is necessary to examine how CAP improves wound healing and which molecular changes occur after the CAP treatment. In the present study we used the second generation MicroPlaSter ß® in analogy to the current clinical standard (2 min treatment time) in order to determine molecular changes induced by CAP using in vitro cell culture studies with human fibroblasts and an in vivo mouse skin wound healing model. Our in vitro analysis revealed that the CAP treatment induces the expression of important key genes crucial for the wound healing response like IL-6, IL-8, MCP-1, TGF-ß1, TGF-ß2, and promotes the production of collagen type I and alpha-SMA. Scratch wound healing assays showed improved cell migration, whereas cell proliferation analyzed by XTT method, and the apoptotic machinery analyzed by protein array technology, was not altered by CAP in dermal fibroblasts. An in vivo wound healing model confirmed that the CAP treatment affects above mentioned genes involved in wound healing, tissue injury and repair. Additionally, we observed that the CAP treatment improves wound healing in mice, no relevant side effects were detected. We suggest that improved wound healing might be due to the activation of a specified panel of cytokines and growth factors by CAP. In summary, our in vitro human and in vivo animal data suggest that the 2 min treatment with the MicroPlaSter ß® is an effective technique for activating wound healing relevant molecules in dermal fibroblasts leading to improved wound healing, whereas the mechanisms which contribute to these observed effects have to be further investigated. PMID:24265766

  18. The Changing Cold Regions Network: Improving the Understanding and Prediction of Changing Land, Water, and Climate in the Mackenzie and Saskatchewan River Basins, Canada

    NASA Astrophysics Data System (ADS)

    DeBeer, C. M.; Wheater, H. S.; Chun, K. P.; Shook, K.; Whitfield, P. H.

    2014-12-01

    Within the cold interior of western and northern Canada, rapid and widespread environmental changes are taking place, which are of serious concern for society and have a range of implications from local to regional and global scales. From a scientific standpoint there is an urgent need to understand the changes and develop improved diagnostic and predictive modelling tools to deal with the uncertainty faced in the future. The Changing Cold Regions Network (CCRN) is a research consortium of over 50 Canadian university and government scientists and international researchers aimed at addressing these issues within the geographic domain of the Mackenzie and Saskatchewan River Basins. CCRN's primary focus is to integrate existing and new experimental data with modelling and remote sensing products to understand, diagnose and predict changing land, water and climate, and their interactions and feedbacks. To support these activities, the network utilizes a suite of 14 world-class water, ecosystem, cryosphere and climate (WECC) observatories across this region that provide exceptional opportunities to observe change, investigate processes and their dynamics, and develop and test environmental models. This talk will briefly describe the CCRN thematic components and WECC observatories, and will then describe some of the observed environmental changes and their linkages across the northern and mountainous parts of the network study domain. In particular, this will include changes in permafrost, terrestrial vegetation, snowcover, glaciers, and river discharge in relation to observed climatic changes across the region. The observations draw on a wide range of literature sources and statistical analyses of federal and provincial regional monitoring network data, while more detailed observations at some of the WECC observatories help to show how these regional changes are manifested at local scales and vice versa. A coordinated special observation and analysis period across all

  19. The Cold War: A Yearbook Perspective.

    ERIC Educational Resources Information Center

    Graebner, William

    1986-01-01

    Shows how the photographs, valedictorian addresses, nicknames, cartoons and other material contained in high school yearbook can yield information regarding the world views of Americans at the start of the Cold War. (JDH)

  20. The Origins of the Cold War.

    ERIC Educational Resources Information Center

    Paterson, Thomas G.

    1986-01-01

    Briefly reviews conventional reasoning about the start of the Cold War. Describes contemporary revisionist views of the Cold War and the reasons they arose. Maintains that American leaders exaggerated the Soviet ideological and military threat, spurring an American arms build-up which ultimately led to the present-day arms race. (JDH)

  1. Project COLD.

    ERIC Educational Resources Information Center

    Kazanjian, Wendy C.

    1982-01-01

    Describes Project COLD (Climate, Ocean, Land, Discovery) a scientific study of the Polar Regions, a collection of 35 modules used within the framework of existing subjects: oceanography, biology, geology, meterology, geography, social science. Includes a partial list of topics and one activity (geodesic dome) from a module. (Author/SK)

  2. Cold Sores

    MedlinePlus

    ... causes oral herpes, or cold sores. Type 1 herpes virus infects more than half of the U.S. population by the time they reach their 20s. Type 2 usually affects the genital area Some people have no symptoms from the ...

  3. Massive cold cloud clusters

    NASA Astrophysics Data System (ADS)

    Toth, L. Viktor; Marton, Gabor; Zahorecz, Sarolta

    2015-08-01

    The all-sky Planck catalogue of Galactic Cold Clumps (PGCC, Planck 2015 results XXVIII 2015) allows an almost unbiased study of the early phases of star-formation in our Galaxy. Several thousand of the clumps have also distance estimates allowing a mass, and density determination. The nature of Planck clumps varies from IRDCs to tiny nearby cold clouds with masses ranging from one to several tens of thousands solar masses. Some of the clumps are embedded in GMCs, others are isolated. Some are close or even very close to OB associations, while others lay far from any UV luminous objects.The small scale clustering of these objects was studied with the improved Minimum Spanning Tree method of Cartwright & Whitworth identifying groups in 3D space. As a result also massive cold cloud clusters were identified. We analyse the MST structures, and discuss their relation to ongoing and future massive star formation.

  4. Bacterial start site prediction.

    PubMed

    Hannenhalli, S S; Hayes, W S; Hatzigeorgiou, A G; Fickett, J W

    1999-09-01

    With the growing number of completely sequenced bacterial genes, accurate gene prediction in bacterial genomes remains an important problem. Although the existing tools predict genes in bacterial genomes with high overall accuracy, their ability to pinpoint the translation start site remains unsatisfactory. In this paper, we present a novel approach to bacterial start site prediction that takes into account multiple features of a potential start site, viz., ribosome binding site (RBS) binding energy, distance of the RBS from the start codon, distance from the beginning of the maximal ORF to the start codon, the start codon itself and the coding/non-coding potential around the start site. Mixed integer programing was used to optimize the discriminatory system. The accuracy of this approach is up to 90%, compared to 70%, using the most common tools in fully automated mode (that is, without expert human post-processing of results). The approach is evaluated using Bacillus subtilis, Escherichia coli and Pyrococcus furiosus. These three genomes cover a broad spectrum of bacterial genomes, since B.subtilis is a Gram-positive bacterium, E.coli is a Gram-negative bacterium and P. furiosus is an archaebacterium. A significant problem is generating a set of 'true' start sites for algorithm training, in the absence of experimental work. We found that sequence conservation between P. furiosus and the related Pyrococcus horikoshii clearly delimited the gene start in many cases, providing a sufficient training set. PMID:10446249

  5. Starting physiology: bioelectrogenesis.

    PubMed

    Baptista, Vander

    2015-12-01

    From a Cartesian perspective of rational analysis, the electric potential difference across the cell membrane is one of the fundamental concepts for the study of physiology. Unfortunately, undergraduate students often struggle to understand the genesis of this energy gradient, which makes the teaching activity a hard task for the instructor. The topic of bioelectrogenesis encompasses multidisciplinary concepts, involves several mechanisms, and is a dynamic process, i.e., it never turns off during the lifetime of the cell. Therefore, to improve the transmission and acquisition of knowledge in this field, I present an alternative didactic model. The design of the model assumes that it is possible to build, in a series of sequential steps, an assembly of proteins within the membrane of an isolated cell in a simulated electrophysiology experiment. Initially, no proteins are inserted in the membrane and the cell is at a baseline energy state; the extracellular and intracellular fluids are at thermodynamic equilibrium. Students are guided through a sequence of four steps that add key membrane transport proteins to the model cell. The model is simple at the start and becomes progressively more complex, finally producing transmembrane chemical and electrical gradients. I believe that this didactic approach helps instructors with a more efficient tool for the teaching of the mechanisms of resting membrane potential while helping students avoid common difficulties that may be encountered when learning this topic. PMID:26628666

  6. Chronic Mild Cold Conditioning Modulates the Expression of Hypothalamic Neuropeptide and Intermediary Metabolic-related Genes and Improves Growth Performances in Young Chicks

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Background: Low environmental temperatures are among the most challenging stressors in poultry industries. Although landmark studies using acute severe cold exposure have been conducted, still the molecular mechanisms underlying cold-stress responses in birds are not completely defined. In the pre...

  7. Hot, Cold, and Really Cold.

    ERIC Educational Resources Information Center

    Leyden, Michael

    1997-01-01

    Describes a physics experiment investigating temperature prediction and the relationship between the physical properties of heat units, melting, dissolving, states of matter, and energy loss. Details the experimental setup, which requires hot and cold water, a thermometer, and ice. Notes that the experiment employs a deliberate counter-intuitive…

  8. 40 CFR 86.236-94 - Engine starting and restarting.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 18 2011-07-01 2011-07-01 false Engine starting and restarting. 86.236... PROGRAMS (CONTINUED) CONTROL OF EMISSIONS FROM NEW AND IN-USE HIGHWAY VEHICLES AND ENGINES Emission... New Medium-Duty Passenger Vehicles; Cold Temperature Test Procedures § 86.236-94 Engine starting...

  9. 40 CFR 86.236-94 - Engine starting and restarting.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 19 2012-07-01 2012-07-01 false Engine starting and restarting. 86.236... PROGRAMS (CONTINUED) CONTROL OF EMISSIONS FROM NEW AND IN-USE HIGHWAY VEHICLES AND ENGINES Emission... New Medium-Duty Passenger Vehicles; Cold Temperature Test Procedures § 86.236-94 Engine starting...

  10. 40 CFR 86.236-94 - Engine starting and restarting.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 19 2013-07-01 2013-07-01 false Engine starting and restarting. 86.236... PROGRAMS (CONTINUED) CONTROL OF EMISSIONS FROM NEW AND IN-USE HIGHWAY VEHICLES AND ENGINES Emission... New Medium-Duty Passenger Vehicles; Cold Temperature Test Procedures § 86.236-94 Engine starting...

  11. 40 CFR 86.236-94 - Engine starting and restarting.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 18 2010-07-01 2010-07-01 false Engine starting and restarting. 86.236... PROGRAMS (CONTINUED) CONTROL OF EMISSIONS FROM NEW AND IN-USE HIGHWAY VEHICLES AND ENGINES Emission... New Medium-Duty Passenger Vehicles; Cold Temperature Test Procedures § 86.236-94 Engine starting...

  12. Smart Start News, 1999.

    ERIC Educational Resources Information Center

    Harris, Monica, Ed.

    1999-01-01

    Smart Start is a comprehensive public-private initiative to help all North Carolina children enter school healthy and ready to succeed, and provides children from birth to age five access to high-quality and affordable child care, health care, and other critical services. This document comprises the first two issues of "Smart Start News," a…

  13. Starting School in August

    ERIC Educational Resources Information Center

    Chmelynski, Carol

    2006-01-01

    In this article, the author discusses the controversial decision of the school board from the Broward County, Florida to start the school year on August 9. School boards across the country that are grappling with the idea of starting school earlier in the year are increasingly running up against strong opposition from parents. In many districts,…

  14. Start with Science

    ERIC Educational Resources Information Center

    Erickson, Susan

    2012-01-01

    The author has found over her 13 years of teaching that starting off the school year with a science investigation has been a great method to learn about her students, to engage them about science before the school year even starts, and to build a foundation for a year of engaging science experiences. This article describes four such activities…

  15. Chilling Out with Colds

    MedlinePlus

    ... most common cold virus, but more than 200 viruses can cause colds. Because there are so many, ... to help you feel better. Take that, cold viruses! continue How Kids Catch Colds Mucus (say: MYOO- ...

  16. Coping with Cold Sores

    MedlinePlus

    ... Here's Help White House Lunch Recipes Coping With Cold Sores KidsHealth > For Kids > Coping With Cold Sores ... sore." What's that? Adam wondered. What Is a Cold Sore? Cold sores are small blisters that is ...

  17. Cold agglutinin disease.

    PubMed

    Swiecicki, Paul L; Hegerova, Livia T; Gertz, Morie A

    2013-08-15

    Cold agglutinin disease is a rare and poorly understood disorder affecting 15% of patients with autoimmune hemolytic anemia. We reviewed the clinical and pathologic features, prognosis, and management in the literature and describe our institutional experience to improve strategies for accurate diagnosis and treatment. Retrospective analysis identified 89 patients from our institution with cold agglutinin disease from 1970 through 2012. Median age at symptom onset was 65 years (range, 41 to 83 years), whereas the median age at diagnosis was 72 years (range, 43 to 91 years). Median survival of all patients was 10.6 years, and 68 patients (76%) were alive 5 years after the diagnosis. The most common symptom was acrocyanosis (n = 39 [44%]), and many had symptoms triggered by cold (n = 35 [39%]) or other factors (n = 20 [22%]). An underlying hematologic disorder was detected in 69 patients (78%). Thirty-six patients (40%) received transfusions during their disease course, and 82% received drug therapy. Rituximab was associated with the longest response duration (median, 24 months) and the lowest proportion of patients needing further treatment (55%). Our institution's experience and review of the literature confirms that early diagnostic evaluation and treatment improves outcomes in cold agglutinin disease. PMID:23757733

  18. Improving the quality of antibiotic prescribing in the NHS by developing a new Antimicrobial Stewardship Programme: Start Smart--Then Focus.

    PubMed

    Ashiru-Oredope, Diane; Sharland, Mike; Charani, Esmita; McNulty, Cliodna; Cooke, Jonathan

    2012-07-01

    There has been dramatic change in antibiotic use in English hospitals. Data from 2004 and 2009 show that the focus on reducing fluoroquinolone and second- and third-generation cephalosporin use seems to have been heeded in NHS secondary care, and has been associated with a substantial decline in hospital Clostridium difficile rates. However, there has been a substantial increase in use of co-amoxiclav, carbapenems and piperacillin/tazobactam. In primary care, antibiotic prescribing fell markedly from 1995 to 2000, but has since risen steadily to levels seen in the early 1990s. There remains a 2-fold variation in antimicrobial prescribing among English General Practices. In 2010, the NHS Atlas of Variation documented a 3-fold variation in the prescription of quinolones and an 18-fold variation in cephalosporins by Primary Care Trusts across England. There is a clear need to improve antimicrobial prescribing. This paper describes the development of new antimicrobial stewardship programmes for primary care and hospitals by the Department of Health's Advisory Committee on Antimicrobial Resistance and Healthcare Associated Infection: Antimicrobial Stewardship in Primary Care Initiative. The secondary care programme promotes the rapid prescription of the right antibiotic at the right dose at the right time, followed by active review for all patients still on antibiotics 48 h after admission. The five options available are to stop, switch to oral, continue and review again, change (if possible to a narrower spectrum) or move to outpatient parenteral antibiotic therapy. A range of audit and outcome tools has been developed, but to maintain optimal antimicrobial usage, monitoring of local and national quantitative and qualitative data on prescribing and consumption is required, linked to the development of key performance indicators in primary, secondary and tertiary care. PMID:22855879

  19. Using a glass fiber separator in a single-chamber air-cathode microbial fuel cell shortens start-up time and improves anode performance at ambient and mesophilic temperatures.

    PubMed

    Zhang, Xiaoyuan; Liang, Peng; Shi, Juan; Wei, Jincheng; Huang, Xia

    2013-02-01

    A shorter start-up time and highly negative anode potentials are needed to improve single-chamber air-cathode microbial fuel cells (MFCs). Using a glass fiber separator reduced the start-up time from 10d to 8d at 20°C, and from 4d to 2d at 30°C, and enhanced coulombic efficiency (CE) from <60% to 89% (20°C) and 87% (30°C). Separators also reduced anode potentials by 20-190mV, charge transfer resistances by 76% (20°C) and 19% (30°C), and increased CV peak currents by 24% (20°C) and 8% (30°C) and the potential range for redox activity (-0.55 to 0.10mV vs. -0.49 to -0.24mV at 20°C). Using a glass fiber separator in an air-cathode MFC, combined with inoculation at a mesophilic temperature, are excellent strategies to shorten start-up time and to enhance anode performance and CE. PMID:23334007

  20. COLD TRAPS

    DOEpatents

    Thompson, W.I.

    1958-09-30

    A cold trap is presented for removing a condensable component from a gas mixture by cooling. It consists of a shell, the exterior surface of which is chilled by a refrigerant, and conductive fins welded inside the shell to condense the gas, and distribute the condensate evenly throughout the length of the trap, so that the trap may function until it becomes completely filled with the condensed solid. The contents may then be removed as either a gas or as a liquid by heating the trap. This device has particuinr use as a means for removing uranium hexafluoride from the gaseous diffusion separation process during equipment breakdown and repair periods.

  1. INEL cold test pit demonstration of improvements in information derived from non-intrusive geophysical methods over buried waste sites. Phase 2, Final report

    SciTech Connect

    Not Available

    1994-04-29

    Under Contract between US DOE Idaho National Engineering Laboratory (INEL) and the Blackhawk Geosciences Division of Coleman Research Corporation (BGD-CRC), geophysical investigations were conducted to improve the detection of buried wastes. Site characterization is a costly and time consuming process with the most costly components being drilling, sampling, and chemical analysis of samples. There is a focused effort at US DOE and other agencies to investigate methodologies that reduce costs and shorten the time between characterization and clean-up. These methodologies take the form of employing non-invasive (geophysical) and minimal invasive (e.g., cone penetrometer driving) techniques of characterization, and implementing a near real-time, rational decision-making process (Expedited Site Characterization). Over the Cold Test Pit (CTP) at INEL, data were acquired with multiple sensors on a dense grid. Over the CTP the interpretations inferred from geophysical data are compared with the known placement of various waste forms in the pit. The geophysical sensors employed were magnetics, frequency and time domain electromagnetics, and ground penetrating radar. Also, because of the high data density acquired, filtering and other data processing and imaging techniques were tested. The conclusions derived from the geophysical surveys were that pit boundaries, berms between cells within the pit, and individual objects placed in the pit were best mapped by the new Geonics EM61 time domain EM metal detector. Part of the reason for the effectiveness of the time domain metal detector is that objects buried in the pit are dominantly metallic. Also, the utility of geophysical data is significantly enhanced by dimensional and 3-dimensional imaging formats. These images will particularly assist remediation engineers in visualizing buried wastes.

  2. Avionics Box Cold Plate Damage Prevention

    NASA Technical Reports Server (NTRS)

    Stambolian, Damon; Larcher, Steven; Henderson, Gena; Tran, Donald

    2011-01-01

    Over the years there have been several occurrences of damage to Space Shuttle Orbiter cold plates during removal and replacement of avionics boxes. Thus a process improvement team was put together to determine ways to prevent these kinds of damage. From this effort there were many solutions including, protective covers, training, and improved operations instructions. The focus of this paper is to explain the cold plate damage problem and the corrective actions for preventing future damage to aerospace avionics cold plate designs.

  3. Head Start Improvement Act of 2014

    THOMAS, 113th Congress

    Rep. Salmon, Matt [R-AZ-5

    2014-04-10

    06/13/2014 Referred to the Subcommittee on Early Childhood, Elementary, and Secondary Education. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  4. Can food vouchers improve nutrition and reduce health inequalities in low-income mothers and young children: a multi-method evaluation of the experiences of beneficiaries and practitioners of the Healthy Start programme in England

    PubMed Central

    2014-01-01

    Background Good nutrition is important during pregnancy, breastfeeding and early life to optimise the health of women and children. It is difficult for low-income families to prioritise spending on healthy food. Healthy Start is a targeted United Kingdom (UK) food subsidy programme that gives vouchers for fruit, vegetables, milk, and vitamins to low-income families. This paper reports an evaluation of Healthy Start from the perspectives of women and health practitioners. Methods The multi-method study conducted in England in 2011/2012 included focus group discussions with 49 health practitioners, an online consultation with 620 health and social care practitioners, service managers, commissioners, and user and advocacy groups, and qualitative participatory workshops with 85 low-income women. Additional focus group discussions and telephone interviews included the views of 25 women who did not speak English and three women from Traveller communities. Results Women reported that Healthy Start vouchers increased the quantity and range of fruit and vegetables they used and improved the quality of family diets, and established good habits for the future. Barriers to registration included complex eligibility criteria, inappropriate targeting of information about the programme by health practitioners and a general low level of awareness among families. Access to the programme was particularly challenging for women who did not speak English, had low literacy levels, were in low paid work or had fluctuating incomes. The potential impact was undermined by the rising price of food relative to voucher value. Access to registered retailers was problematic in rural areas, and there was low registration among smaller shops and market stalls, especially those serving culturally diverse communities. Conclusions Our evaluation of the Healthy Start programme in England suggests that a food subsidy programme can provide an important nutritional safety net and potentially improve

  5. The Texas Head Start Metro Models.

    ERIC Educational Resources Information Center

    Riley, Mary Tom, Ed.; Flores, Alfredo R., Ed.

    The Texas Metro Network (TMN) is an informal group of Head Start Directors and Executive Directors organized for the purposes of improving the delivery of training and technical assistance and for assisting communication between large scale Head Start programs in the metropolitan areas of Texas. In pursuit of these aims, each member unit of the…

  6. Constitutive expression of DaCBF7, an Antarctic vascular plant Deschampsia antarctica CBF homolog, resulted in improved cold tolerance in transgenic rice plants.

    PubMed

    Byun, Mi Young; Lee, Jungeun; Cui, Li Hua; Kang, Yoonjee; Oh, Tae Kyung; Park, Hyun; Lee, Hyoungseok; Kim, Woo Taek

    2015-07-01

    Deschampsia antarctica is an Antarctic hairgrass that grows on the west coast of the Antarctic peninsula. In this report, we have identified and characterized a transcription factor, D. antarctica C-repeat binding factor 7 (DaCBF7), that is a member of the monocot group V CBF homologs. The protein contains a single AP2 domain, a putative nuclear localization signal, and the typical CBF signature. DaCBF7, like other monocot group V homologs, contains a distinct polypeptide stretch composed of 43 amino acids in front of the AP2 motif. DaCBF7 was predominantly localized to nuclei and interacted with the C-repeat/dehydration responsive element (CRT/DRE) core sequence (ACCGAC) in vitro. DaCBF7 was induced by abiotic stresses, including drought, cold, and salinity. To investigate its possible cellular role in cold tolerance, a transgenic rice system was employed. DaCBF7-overexpressing transgenic rice plants (Ubi:DaCBF7) exhibited markedly increased tolerance to cold stress compared to wild-type plants without growth defects; however, overexpression of DaCBF7 exerted little effect on tolerance to drought or salt stress. Transcriptome analysis of a Ubi:DaCBF7 transgenic line revealed 13 genes that were up-regulated in DaCBF7-overexpressing plants compared to wild-type plants in the absence of cold stress and in short- or long-term cold stress. Five of these genes, dehydrin, remorin, Os03g63870, Os11g34790, and Os10g22630, contained putative CRT/DRE or low-temperature responsive elements in their promoter regions. These results suggest that overexpression of DaCBF7 directly and indirectly induces diverse genes in transgenic rice plants and confers enhanced tolerance to cold stress. PMID:26025521

  7. Head Start Curriculum Guide.

    ERIC Educational Resources Information Center

    Smith, Clare Coe; And Others

    One of a series of guides for preschool teachers and aides, the book offers a Head Start curriculum guide to help achieve goals regarding social behavior, general attitudes, academic skills, health, and parent development. Information on curriculum is divided into areas of bloc time outline, classroom arrangement, building concepts (such as…

  8. Home Start Evaluation Study.

    ERIC Educational Resources Information Center

    High/Scope Educational Research Foundation, Ypsilanti, MI.

    Case studies of seven Home Start programs are given as the third section of an evaluation study. Communities involved are Huntsville, Alabama; Fairbanks, Alaska; Fort Defiance, Arizona; Dardanelle, Arkansas; Wichita, Kansas; Gloucester, Massachusetts; and Reno, Nevada. Although each study varies in format, each describes in detail the degree and…

  9. Blogs: Getting Started

    ERIC Educational Resources Information Center

    Dyrud, Marilyn A.; Worley, Rebecca B.; Schultz, Benjamin

    2005-01-01

    Blogs are communication tools, they serve as vehicles to transmit messages. Before deciding to blog, one needs to devise a strategy on how this medium will fit in with his or her communication needs. This will also help later in deciding which features one will need to include in his or her blog. This article discusses ways on how to start and…

  10. Where Do We Start?

    ERIC Educational Resources Information Center

    Zuk, Evelyn M.

    1976-01-01

    Guidelines for starting a public school adult education program are presented and discuss the collection of basic data on community characteristics, community involvement, program administration and funding, curriculum, teacher hiring, program-school relationship, enrollment, policies, and community advisory board. (LH)

  11. Starting in School

    ERIC Educational Resources Information Center

    Albertine, Susan

    2012-01-01

    Through its signature initiative, Liberal Education and America's Promise (LEAP), the Association of American Colleges and Universities (AAC&U) is promoting a vision for learning that begins in school: Starting in School . . . Rigorous and rich curriculum focused on the essential learning outcomes; comprehensive, individualized, and…

  12. Starting Trees from Cuttings.

    ERIC Educational Resources Information Center

    Kramer, David C.

    1983-01-01

    Describes a procedure for starting tree cuttings from woody plants, explaining "lag time," recommending materials, and giving step-by-step instructions for rooting and planting. Points out species which are likely candidates for cuttings and provides tips for teachers for developing a unit. (JM)

  13. Cold adaptation increases rates of nutrient flow and metabolic plasticity during cold exposure in Drosophila melanogaster.

    PubMed

    Williams, Caroline M; McCue, Marshall D; Sunny, Nishanth E; Szejner-Sigal, Andre; Morgan, Theodore J; Allison, David B; Hahn, Daniel A

    2016-09-14

    Metabolic flexibility is an important component of adaptation to stressful environments, including thermal stress and latitudinal adaptation. A long history of population genetic studies suggest that selection on core metabolic enzymes may shape life histories by altering metabolic flux. However, the direct relationship between selection on thermal stress hardiness and metabolic flux has not previously been tested. We investigated flexibility of nutrient catabolism during cold stress in Drosophila melanogaster artificially selected for fast or slow recovery from chill coma (i.e. cold-hardy or -susceptible), specifically testing the hypothesis that stress adaptation increases metabolic turnover. Using (13)C-labelled glucose, we first showed that cold-hardy flies more rapidly incorporate ingested carbon into amino acids and newly synthesized glucose, permitting rapid synthesis of proline, a compound shown elsewhere to improve survival of cold stress. Second, using glucose and leucine tracers we showed that cold-hardy flies had higher oxidation rates than cold-susceptible flies before cold exposure, similar oxidation rates during cold exposure, and returned to higher oxidation rates during recovery. Additionally, cold-hardy flies transferred compounds among body pools more rapidly during cold exposure and recovery. Increased metabolic turnover may allow cold-adapted flies to better prepare for, resist and repair/tolerate cold damage. This work illustrates for the first time differences in nutrient fluxes associated with cold adaptation, suggesting that metabolic costs associated with cold hardiness could invoke resource-based trade-offs that shape life histories. PMID:27605506

  14. Cold symptoms (image)

    MedlinePlus

    Colds are caused by a virus and can occur year-round. The common cold generally involves a runny nose, nasal congestion, and ... symptoms include sore throat, cough, and headache. A cold usually lasts about 7 days, with perhaps a ...

  15. Colds and flus - antibiotics

    MedlinePlus

    Antibiotics - colds and flu ... treat infections that are caused by a virus. Colds and flu are caused by viruses. If you ... Hamilton A. Treatments for symptoms of the common cold. Am Fam Physician. 2013;88(12):Online. PMID: ...

  16. Vitamin C and colds

    MedlinePlus

    Colds and vitamin C ... belief that vitamin C can cure the common cold , research about this claim is conflicting. Large doses ... vitamin C may help reduce how long a cold lasts, but they do not appear to protect ...

  17. Cough & Cold Medicine Abuse

    MedlinePlus

    ... I Help a Friend Who Cuts? Cough & Cold Medicine Abuse KidsHealth > For Teens > Cough & Cold Medicine Abuse ... DXM Why Do People Use Cough and Cold Medicines to Get High? There's an ingredient in many ...

  18. Cold-batter mincing of hot-boned and crust-freezing air-chilled turkey breast improved meat turnover time and product quality.

    PubMed

    Medellin-Lopez, M; Sansawat, T; Strasburg, G; Marks, B P; Kang, I

    2014-03-01

    The purpose of this research was to evaluate the combined effects of turkey hot-boning and cold-batter mincing technology on acceleration of meat turnover and meat quality improvement. For each of 3 replications, 15 turkeys were slaughtered and eviscerated. Three of the eviscerated carcasses were randomly assigned to water-immersion chilling for chill-boning (CB) and the remaining were immediately hot-boned (HB), half of which were used without chilling whereas the remaining were subjected to crust-freezing air chilling (CFAC) in an air-freezing room (1.0 m/s, -12°C) with/without 1/4; sectioning (HB-1/4;CFAC, HB-CFAC). As a result, CB and HB breasts were minced using 1 of 5 treatments: (1) CB and traditional mincing (CB-T), (2) HB and mincing with no chilling (HB-NC), (3) HB and mincing with CO2 (HB-CO2), (4) HB and mincing after CFAC (HB-CFAC), and (5) HB and mincing after quarter sectioning and CFAC (HB-1/4;CFAC). Traditional water-immersion chilling took an average of 5.5 h to reduce the breast temperature to 4°C, whereas HB-CFAC and HB-1/4;CFAC took 1.5 and 1 h, respectively. The breast of HB-CFAC and HB-1/4;CFAC showed significantly higher pH (6.0-6.1), higher fragmentation index (196-198), and lower R-value (1.0-1.1; P < 0.05) than those of the CB controls. No significant differences (P > 0.05) in sarcomere length were seen between CB-T and HB-CFAC filets regardless of quarter sectioning. When muscle was minced, the batter pH (5.9) of CB-T was significantly lower (P < 0.05) than those (6.1-6.3) of HB-NC, HB-CO2, and HB-1/4;CFAC, with the intermediate pH (6.0) seen for the HB-CFAC. When meat batters were cooked, higher cooking yield (90 - 91%; P < 0.05) was found in HB-CFAC, HB-1/4;CFAC, and HB-CO2, followed by HB-NC (90%) and finally CB-T (86%). Stress values (47-51 kPa) of HB-CFAC gels were significantly higher (P < 0.05) than those of CB-T (30 kPa) and HB-NC (36 kPa). A similar trend was found in strain values. PMID:24604866

  19. Starting New Schools: Lessons for Success.

    ERIC Educational Resources Information Center

    Jennings, Wayne B.

    Arguments for beginning new schools as a robust alternative to the incremental improvement of existing schools are presented in this paper. The educational improvement approach of starting new schools or programs, rather than making incremental improvements or generating comprehensive change in existing schools, is advocated. Two major types of…

  20. Toxicity evaluation and hazard review Cold Smoke

    SciTech Connect

    Archuleta, M.M.; Stocum, W.E.

    1993-12-01

    Cold Smoke is a dense white smoke produced by the reaction of titanium tetrachloride and aqueous ammonia aerosols. Early studies on the toxicity of this nonpyrotechnically generated smoke indicated that the smoke itself is essentially non-toxic (i.e. exhibits to systemic toxicity or organ damage due to exposure) under normal deployment conditions. The purpose of this evaluation was to review and summarize the recent literature data available on the toxicity of Cold Smoke, its chemical constituents, and its starting materials.

  1. School start times for adolescents.

    PubMed

    2014-09-01

    The American Academy of Pediatrics recognizes insufficient sleep in adolescents as an important public health issue that significantly affects the health and safety, as well as the academic success, of our nation's middle and high school students. Although a number of factors, including biological changes in sleep associated with puberty, lifestyle choices, and academic demands, negatively affect middle and high school students' ability to obtain sufficient sleep, the evidence strongly implicates earlier school start times (ie, before 8:30 am) as a key modifiable contributor to insufficient sleep, as well as circadian rhythm disruption, in this population. Furthermore, a substantial body of research has now demonstrated that delaying school start times is an effective countermeasure to chronic sleep loss and has a wide range of potential benefits to students with regard to physical and mental health, safety, and academic achievement. The American Academy of Pediatrics strongly supports the efforts of school districts to optimize sleep in students and urges high schools and middle schools to aim for start times that allow students the opportunity to achieve optimal levels of sleep (8.5-9.5 hours) and to improve physical (eg, reduced obesity risk) and mental (eg, lower rates of depression) health, safety (eg, drowsy driving crashes), academic performance, and quality of life. PMID:25156998

  2. Cold vacuum drying facility site evaluation report

    SciTech Connect

    Diebel, J.A.

    1996-03-11

    In order to transport Multi-Canister Overpacks to the Canister Storage Building they must first undergo the Cold Vacuum Drying process. This puts the design, construction and start-up of the Cold Vacuum Drying facility on the critical path of the K Basin fuel removal schedule. This schedule is driven by a Tri-Party Agreement (TPA) milestone requiring all of the spent nuclear fuel to be removed from the K Basins by December, 1999. This site evaluation is an integral part of the Cold Vacuum Drying design process and must be completed expeditiously in order to stay on track for meeting the milestone.

  3. Cold atoms coupled with mechanical oscillators

    NASA Astrophysics Data System (ADS)

    Valencia, Jose; Montoya, Cris; Ranjit, Gambhir; Geraci, Andrew; Eardley, Matt; Kitching, John

    2015-05-01

    Mechanical resonators can be used to probe and manipulate atomic spins with nanometer spatial resolution and single-spin sensitivity, ultimately enabling new approaches in neutral-atom quantum computation, quantum simulation, or precision sensing. We describe our experiment that manipulates the spin of trapped, cold Rb atoms using magnetic material on a cantilever. Cold atoms can also be used as a coolant for mechanical resonators: we estimate that ground state cooling of an optically trapped nano-sphere is achievable when starting at room temperature, by sympathetic cooling of a cold atomic gas optically coupled to the nanoparticle.

  4. When to Start Antiretroviral Therapy

    MedlinePlus

    ... away. What conditions increase the need to start ART? HIV-infected people with the following conditions should ... consider starting ART immediately. Once a person starts ART, why is medication adherence important? ART is a ...

  5. Physiological characteristics of cold acclimatization in man

    NASA Astrophysics Data System (ADS)

    Mathew, Lazar; Purkayastha, S. S.; Jayashankar, A.; Nayar, H. S.

    1981-09-01

    Studies were conducted on 15 healthy young soldiers to evaluate the effect of a cold acclimatization schedule on the thermoregulatory and metabolic activity on exposure to acute cold stress. These men were exposed to cold (10‡C) for 4 h daily wearing only shorts for 21 days, in a cold chamber. They were subjected to a standard cold test at 10 ± 1‡C the day 1, 6, 11 and 21. The subjects were made to relax in a thermoneutral room (26 28‡C) for 1 h and their heart rate, blood pressure, oxygen consumption, oral temperature, mean skin temperature, mean body temperature, peripheral temperatures, and shivering activity were recorded. Then they were exposed to 10‡C and measurements were repeated at 30 min intervals, for 2 h. The cold induced vasodilatation (CIVD), cold pressor response and thermoregulatory efficiency tests were measured initially and at the end of acclimatization schedule. The data show that the procedure resulted in elevated resting metabolism, less fall in body temperature during acute cold stress, reduction in shivering, improvement in CIVD and thermoregulatory efficiency and less rise in BP and HR during cold pressor response. The data suggest the possibility of cold acclimatization in man by repeated exposure to moderately severe cold stress.

  6. Enceladus: Starting Hydrothermal Activity

    NASA Technical Reports Server (NTRS)

    Matson, D. L.; Castillo-Rogez, J. C.; Johnson, T. V.; Lunine, J. I.; Davies, A. G.

    2011-01-01

    We describe a process for starting the hydrothermal activity in Enceladus' South Polar Region. The process takes advantage of fissures that reach the water table, about 1 kilometer below the surface. Filling these fissures with fresh ocean water initiates a flow of water up from an ocean that can be self-sustaining. In this hypothesis the heat to sustain the thermal anomalies and the plumes comes from a slightly warm ocean at depth. The heat is brought to the surface by water that circulates up, through the crust and then returns to the ocean.

  7. Synthesis of the heaviest nuclei in cold fusion reactions

    NASA Astrophysics Data System (ADS)

    Münzenberg, G.; Morita, K.

    2015-12-01

    Cold fusion of heavy ions paved the way to superheavy elements. It was proposed by Yu.Ts. Oganessian more than forty years ago in 1974 [1,2]. First experiments were carried out at JINR Dubna, starting with the reaction 40Ar + 208Pb → 248Fm* where several hundreds to thousand atoms were produced on one day. The large production rate indicating an enhancement of the fusion cross section, especially for the evaporation of two or three neutrons, proved the concept of cold-fusion with the use of the doubly magic nucleus 208Pb as a target. The Dubna experiments were extended to the transactinide region beyond rutherfordium. The breakthrough came with the separation in-flight. Two different approaches were used: kinematic separation with the velocity filter SHIP [3] at GSI Darmstadt, and with the gasfilled separator GARIS [4,5] at RIKEN. With SHIP the concept of cold fusion of massive nuclear systems was convincingly confirmed by the observation of the one-neutron evaporation channel in the production of 247Rf in an irradiation of 208Pb with 50Ti [6] in 1981 which opened the way to the transactinide region. At SHIP the elements bohrium (107) to copernicium (112) were discovered [7]. A new closed shell region around hassium was found. The RIKEN experiments started in 2002. They confirmed the GSI results and in addition improved the data on structure and production of elements hassium to copernicium significantly. The heaviest element ever created in a cold fusion reaction, Z = 113, was observed at GARIS [8,9].

  8. Minnesota: Early Head Start Initiatiive

    ERIC Educational Resources Information Center

    Center for Law and Social Policy, Inc. (CLASP), 2012

    2012-01-01

    Minnesota provides supplemental state funding to existing federal Head Start and Early Head Start (EHS) grantees to increase their capacity to serve additional infants, toddlers, and pregnant women. The initiative was started in 1997 when the state legislature earmarked $1 million of the general state Head Start supplemental funds for children…

  9. Missouri: Early Head Start Initiative

    ERIC Educational Resources Information Center

    Center for Law and Social Policy, Inc. (CLASP), 2012

    2012-01-01

    Missouri's Early Head Start/Child Care Partnership Project expands access to Early Head Start (EHS) services for children birth to age 3 by developing partnerships between federal Head Start, EHS contractors, and child care providers. Head Start and EHS contractors that participate in the initiative provide services through community child care…

  10. 34 CFR 200.16 - Starting points.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Starting points. 200.16 Section 200.16 Education Regulations of the Offices of the Department of Education OFFICE OF ELEMENTARY AND SECONDARY EDUCATION, DEPARTMENT OF EDUCATION TITLE I-IMPROVING THE ACADEMIC ACHIEVEMENT OF THE DISADVANTAGED Improving Basic Programs Operated by Local Educational...