Science.gov

Sample records for integrated systems research

  1. Academic Research Integration System

    ERIC Educational Resources Information Center

    Surugiu, Iula; Velicano, Manole

    2008-01-01

    This paper comprises results concluding the research activity done so far regarding enhanced web services and system integration. The objective of the paper is to define the software architecture for a coherent framework and methodology for enhancing existing web services into an integrated system. This document presents the research work that has…

  2. CLARA: an integrated clinical research administration system.

    PubMed

    Bian, Jiang; Xie, Mengjun; Hogan, William; Hutchins, Laura; Topaloglu, Umit; Lane, Cheryl; Holland, Jennifer; Wells, Thomas

    2014-10-01

    Administration of human subject research is complex, involving not only the institutional review board but also many other regulatory and compliance entities within a research enterprise. Its efficiency has a direct and substantial impact on the conduct and management of clinical research. In this paper, we report on the Clinical Research Administration (CLARA) platform developed at the University of Arkansas for Medical Sciences. CLARA is a comprehensive web-based system that can streamline research administrative tasks such as submissions, reviews, and approval processes for both investigators and different review committees on a single integrated platform. CLARA not only helps investigators to meet regulatory requirements but also provides tools for managing other clinical research activities including budgeting, contracting, and participant schedule planning. PMID:24778201

  3. Integrating Spaceflight Human System Risk Research

    NASA Technical Reports Server (NTRS)

    Mindock, Jennifer; Lumpkins, Sarah; Anton, Wilma; Havenhill, Maria; Shelhamer, Mark; Canga, Michael

    2016-01-01

    NASA is working to increase the likelihood of human health and performance success during exploration missions as well as to maintain the subsequent long-term health of the crew. To manage the risks in achieving these goals, a system modelled after a Continuous Risk Management framework is in place. "Human System Risks" (Risks) have been identified, and approximately 30 are being actively addressed by NASA's Human Research Program (HRP). Research plans for each of HRP's Risks have been developed and are being executed. Inter-disciplinary ties between the research efforts supporting each Risk have been identified; however, efforts to identify and benefit from these connections have been mostly ad hoc. There is growing recognition that solutions developed to address the full set of Risks covering medical, physiological, behavioural, vehicle, and organizational aspects of exploration missions must be integrated across Risks and disciplines. This paper discusses how a framework of factors influencing human health and performance in space is being applied as the backbone for bringing together sometimes disparate information relevant to the individual Risks. The resulting interrelated information enables identification and visualization of connections between Risks and research efforts in a systematic and standardized manner. This paper also discusses the applications of the visualizations and insights into research planning, solicitation, and decision-making processes.

  4. Integrating Spaceflight Human System Risk Research

    NASA Technical Reports Server (NTRS)

    Mindock, J.; Lumpkins, S.; Anton, W.; Havenhill, M.; Shelhamer, M.; Canga, M.

    2016-01-01

    NASA is working to increase the likelihoods of human health and performance success during exploration missions, and subsequent crew long-term health. To manage the risks in achieving these goals, a system modeled after a Continuous Risk Management framework is in place. "Human System Risks" (Risks) have been identified, and approximately 30 are being actively addressed by NASA's Human Research Program (HRP). Research plans for each of HRP's Risks have been developed and are being executed. Ties between the research efforts supporting each Risk have been identified, however, this has been in an ad hoc fashion. There is growing recognition that solutions developed to address the full set of Risks covering medical, physiological, behavioral, vehicle, and organizational aspects of the exploration missions must be integrated across Risks and disciplines. We will discuss how a framework of factors influencing human health and performance in space is being applied as the backbone for bringing together sometimes disparate information relevant to the individual Risks. The resulting interrelated information is allowing us to identify and visualize connections between Risks and research efforts in a systematic and standardized way. We will discuss the applications of the visualizations and insights to research planning, solicitation, and decision-making processes.

  5. Integrated Crop/Livestock Systems Research: Practical research considerations

    Technology Transfer Automated Retrieval System (TEKTRAN)

    There are many reasons for the paucity of integrated crop/livestock research and associated publications. Integrated/crop livestock experiments that involve adequate treatments and replications, as perceived by both crop and animal scientists, require large acreages, many animals, considerable labor...

  6. Aeronautics Research Mission Directorate Integrated Systems Research Program (ISRP) and UAS Integration in the NAS Project

    NASA Technical Reports Server (NTRS)

    Wolfe, Jean

    2010-01-01

    Program Goal: Conduct research at an integrated system-level on promising concepts and technologies and explore, assess, or demonstrate the benefits in a relevant environment.Criteria for selection of projects for Integrated Systems Research: a) Technology has attained enough maturity in the foundational research program that they merit more in-depth evaluation at an integrated system level in a relevant environment. b) Technologies which systems analysis indicates have the most potential for contributing to the simultaneous attainment of goals. c) Technologies identified through stakeholder input as having potential for simultaneous attainment of goals. d) Research not being done by other government agencies and appropriate for NASA to conduct. e) Budget augmentation. Environmentally Responsible Aviation (ERA) Project Explore and assess new vehicle concepts and enabling technologies through system-level experimentation to simultaneously reduce fuel burn, noise, and emissions Unmanned Aircraft Systems (UAS) Integration in the National Airspace System (NAS) Project Contribute capabilities that reduce technical barriers related to the safety and operational challenges associated with enabling routine UAS access to the NAS Innovative Concepts for Green Aviation (ICGA) Project Spur innovation by offering research opportunities to the broader aeronautics community through peer-reviewed proposals, with a focus on making aviation more eco-friendly. Establish incentive prizes similar to the Centennial Challenges and sponsor innovation demonstrations of selected technologies that show promise of reducing aviation s impact on the environment

  7. Integrated Advanced Energy Systems Research at IIT

    SciTech Connect

    Hamid Arastoopour

    2010-09-30

    This report consists of Two research projects; Sustainable Buildings and Hydrogen Storage. Sustainable Building Part includes: Wind and the self powered built environment by professor P. Land and his research group and experimental and computational works by professor D. Rempfer and his research group. Hydrogen Storage part includes: Hydrogen Storage Using Mg-Mixed Metal Hydrides by professor H. Arastoopour and his research team and Carbon Nanostructure as Hydrogen Storage Material by professor J. Prakash and his research team.

  8. NASA Integrated Systems Research with an Environmental Focus

    NASA Technical Reports Server (NTRS)

    Wolfe, Jean; Collier, Fay

    2010-01-01

    This slide presentation reviews the Integrated Systems Research Program (ISRP) with a focus on the work being done on reduction of environmental impact from aeronautics. The focus of the ISRP is to Conduct research at an integrated system-level on promising concepts and technologies and explore, assess, or demonstrate the benefits in a relevant environment. The presentation reviews the criteria for an ISRP project, and discusses the Environmentally Responsible Aviation (ERA) project, and the technical challenges.

  9. Integrated voice and visual systems research topics

    NASA Technical Reports Server (NTRS)

    Williams, Douglas H.; Simpson, Carol A.

    1986-01-01

    A series of studies was performed to investigate factors of helicopter speech and visual system design and measure the effects of these factors on human performance, both for pilots and non-pilots. The findings and conclusions of these studies were applied by the U.S. Army to the design of the Army's next generation threat warning system for helicopters and to the linguistic functional requirements for a joint Army/NASA flightworthy, experimental speech generation and recognition system.

  10. Conducting Institutional Research Using an Integrated Student Information System.

    ERIC Educational Resources Information Center

    Yost, Michael

    The use of an integrated student information system (ISIS) to conduct institutional research at Trinity University is discussed. The types of data contained in the system, which has 59 files, include: student characteristics, recruitment, financial aid, registration, faculty load, and class scheduling. The data for students, faculty, departments,…

  11. [A research on healthcare integrating model of medical information system].

    PubMed

    Lü, Xudong; Duan, Huilong

    2005-02-01

    System integration is inevitable since there are lots of heterogeneous medical information systems in the complicated medical environment. The current medical communication standards often focus on one aspect of the integration and do not provide a general scheme. Based on the analysis of the application of medical integration, the medical integration model HIM (Healthcare integrating model) is put forward, and the dataflow integration framework, function integration framework and interface integration framework in the HIM are designed subsequently. HIM provides a 3-D scheme for the integration of medical information systems, which not only contains the three aspects of integration application vertically, but covers the whole medical area horizontally. PMID:15762128

  12. Integrated testing and verification system for research flight software

    NASA Technical Reports Server (NTRS)

    Taylor, R. N.

    1979-01-01

    The MUST (Multipurpose User-oriented Software Technology) program is being developed to cut the cost of producing research flight software through a system of software support tools. An integrated verification and testing capability was designed as part of MUST. Documentation, verification and test options are provided with special attention on real-time, multiprocessing issues. The needs of the entire software production cycle were considered, with effective management and reduced lifecycle costs as foremost goals.

  13. Integrated modelling of ecosystem services and energy systems research

    NASA Astrophysics Data System (ADS)

    Agarwala, Matthew; Lovett, Andrew; Bateman, Ian; Day, Brett; Agnolucci, Paolo; Ziv, Guy

    2016-04-01

    The UK Government is formally committed to reducing carbon emissions and protecting and improving natural capital and the environment. However, actually delivering on these objectives requires an integrated approach to addressing two parallel challenges: de-carbonising future energy system pathways; and safeguarding natural capital to ensure the continued flow of ecosystem services. Although both emphasise benefiting from natural resources, efforts to connect natural capital and energy systems research have been limited, meaning opportunities to improve management of natural resources and meet society's energy needs could be missed. The ecosystem services paradigm provides a consistent conceptual framework that applies in multiple disciplines across the natural and economic sciences, and facilitates collaboration between them. At the forefront of the field, integrated ecosystem service - economy models have guided public- and private-sector decision making at all levels. Models vary in sophistication from simple spreadsheet tools to complex software packages integrating biophysical, GIS and economic models and draw upon many fields, including ecology, hydrology, geography, systems theory, economics and the social sciences. They also differ in their ability to value changes in natural capital and ecosystem services at various spatial and temporal scales. Despite these differences, current models share a common feature: their treatment of energy systems is superficial at best. In contrast, energy systems research has no widely adopted, unifying conceptual framework that organises thinking about key system components and interactions. Instead, the literature is organised around modelling approaches, including life cycle analyses, econometric investigations, linear programming and computable general equilibrium models. However, some consistencies do emerge. First, often contain a linear set of steps, from exploration to resource supply, fuel processing, conversion

  14. Research on information fusion for engineering system integrated health management

    NASA Astrophysics Data System (ADS)

    Gao, Zhanbao; Li, Xingshan; Sun, Cong; Liu, Qi

    2006-11-01

    Integrated Health Management technology is the emerging paradigm in system supervision and maintenance area, and it is the key to achieving true condition-based maintenance. But this task is complicated by the extremely large amount of the data available, the existence of uncertainties, and interactive engineering system operational conditions. Therefore, it is reasonable to research the health information fusion technology to achieve better performance and a higher level of autonomy for IHM system. This paper analyses the requirements of the information fusion in an IHM system, describes the fusion application areas, proposes the Health Sensing Unit (HSU) concept, and designs the distributed hierarchical fusion architecture. Using the confidence distance matrix as the measure of HSU's performance, this paper proposes a fusion algorithm to fuse multiple HSUs' output, and figure out the system health index according to the maximum likelihood principle. The simulation result yields conclusive evidence that fusion can be very valuable in the IHM technology for the system supervision and maintenance.

  15. The Role of Research in Integrated Health Care Systems: The HMO Research Network

    PubMed Central

    Vogt, Thomas M; Lafata, Jennifer Elston; Tolsma, Dennis D; Greene, Sarah M

    2004-01-01

    Integrated care systems have unique advantages for conducting research. The HMO Research Network (HMORN) includes research centers associated with 13 large integrated care systems whose research focuses on improving health and health care delivery using the extraordinary platform provided by these health systems. We conducted literature reviews and surveys and interviews with directors of HMORN research centers, research investigators, and selected support staff in order to identify the characteristics of the research in HMORN centers and to present examples of how this research has affected health and health policy. The 13 HMORN member health systems deliver health care to 13 million people. HMORN research centers have access to large, defined populations, comprehensive medical information, extensive computerized data systems and to medical care delivery systems that offer extraordinary research opportunities. HMORN centers publish about 1200 scientific articles each year and received about $180 million in external research funding in 2002, most of it from NIH, CDC, and other federal sources. More than 2000 research studies are currently underway at these centers, which employ approximately 1500 persons in the research activities. HMORN research centers have had a profound impact on health policy and care. New technologies are steadily expanding the research capacities of these research groups. Increased collaboration between academic and HMO researchers would enhance the work of both. PMID:26705313

  16. ATLAS from Data Research Associates: A Fully Integrated Automation System.

    ERIC Educational Resources Information Center

    Mellinger, Michael J.

    1987-01-01

    This detailed description of a fully integrated, turnkey library system includes a complete profile of the system (functions, operational characteristics, hardware, operating system, minimum memory and pricing); history of the technologies involved; and descriptions of customer services and availability. (CLB)

  17. Integrated obesity care management system -implementation and research protocol

    PubMed Central

    Baillargeon, Jean-Patrice; Carpentier, André; Donovan, Denise; Fortin, Martin; Grant, Andrew; Simoneau-Roy, Judith; St-Cyr-Tribble, Denise; Xhignesse, Mariane; Langlois, Marie-France

    2007-01-01

    Background Nearly 50% of Canadians are overweight and their number is increasing rapidly. The majority of obese subjects are treated by primary care physicians (PCPs) who often feel uncomfortable with the management of obesity. The current research proposal is aimed at the development and implementation of an innovative, integrated, interdisciplinary obesity care management system involving both primary and secondary care professionals. Methods We will use both action and evaluative research in order to achieve the following specific objectives. The first one is to develop and implement a preceptorship-based continuing medical education (CME) program complemented by a web site for physicians and nurses working in Family Medicine Groups (FMGs). This CME will be based on needs assessment and will be validated by one FMG using questionnaires and semi structured interviews. Also, references and teaching tools will be available for participants on the web site. Our second objective is to establish a collaborative intra and inter-regional interdisciplinary network to enable on-going expertise update and networking for FMG teams. This tool consists of a discussion forum and monthly virtual meetings of all participants. Our third objective is to evaluate the implementation of our program for its ability to train 8 FMGs per year, the access and utilization of electronic tools and the participants' satisfaction. This will be measured with questionnaires, web logging tools and group interviews. Our fourth objective is to determine the impact for the participants regarding knowledge and expertise, attitudes and perceptions, self-efficacy for the management of obesity, and changes in FMG organization for obesity management. Questionnaires and interviews will be used for this purpose. Our fifth objective is to deliver transferable knowledge for health professionals and decision-makers. Strategies and pitfalls of setting up this program will also be identified. Conclusion This

  18. Building system integration research: recommendations for a US Department of Energy multiyear program plan

    SciTech Connect

    Not Available

    1986-01-01

    This plan describes the scope, technical content, and resources required to conduct the Building System Integration (BSI) research program during FY 1987 through 1991. System integration research is defined, the need for the research is discussed, its benefits are outlined, and the history of building system integration research is summarized. The program scope, the general approach taken in developing this program plan, and the plan's contents are also described.

  19. Integration of Data Systems and Technology Improves Research and Collaboration for a Superfund Research Center

    PubMed Central

    Hobbie, Kevin A.; Peterson, Elena S.; Barton, Michael L.; Waters, Katrina M.; Anderson, Kim A.

    2012-01-01

    Large collaborative centers are a common model for accomplishing integrated environmental health research. These centers often include various types of scientific domains (e.g. chemistry, biology, bioinformatics) that are integrated to solve some of the nation’s key economic or public health concerns. The Superfund Research Center (SRP) at Oregon State University (OSU) is one such center established in 2008 to study the emerging health risks of polycyclic aromatic hydrocarbons while utilizing new technologies both in the field and laboratory. With outside collaboration at remote institutions, success for the center as a whole depends on the ability to effectively integrate data across all research projects and support cores. Therefore, the OSU SRP center developed a system that integrates environmental monitoring data with analytical chemistry data and downstream bioinformatics and statistics to enable complete ‘source to outcome’ data modeling and information management. This article describes the development of this integrated information management system that includes commercial software for operational laboratory management and sample management in addition to open source custom built software for bioinformatics and experimental data management. PMID:22651935

  20. Moving from Intersection to Integration: Public Health Law Research and Public Health Systems and Services Research

    PubMed Central

    Burris, Scott; Mays, Glen P; Douglas Scutchfield, F; Ibrahim, Jennifer K

    2012-01-01

    Context For three decades, experts have been stressing the importance of law to the effective operation of public health systems. Most recently, in a 2011 report, the Institute of Medicine recommended a review of state and local public health laws to ensure appropriate authority for public health agencies; adequate access to legal counsel for public health agencies; evaluations of the health effects and costs associated with legislation, regulations, and policies; and enhancement of research methods to assess the strength of evidence regarding the health effects of public policies. These recommendations, and the continued interest in law as a determinant of health system performance, speak to the need for integrating the emerging fields of Public Health Law Research (PHLR) and Public Health Systems and Services Research (PHSSR). Methods Expert commentary. Findings This article sets out a unified framework for the two fields and a shared research agenda built around three broad inquiries: (1) the structural role of law in shaping the organization, powers, prerogatives, duties, and limitations of public health agencies and thereby their functioning and ultimately their impact on public health (“infrastructure”); (2) the mechanisms through which public health system characteristics influence the implementation of interventional public health laws (“implementation”); and (3) the individual and system characteristics that influence the ability of public health systems and their community partners to develop and secure enactment of legal initiatives to advance public health (“innovation”). Research to date has laid a foundation of evidence, but progress requires better and more accessible data, a new generation of researchers comfortable in both law and health research, and more rigorous methods. Conclusions The routine integration of law as a salient factor in broader PHSSR studies of public health system functioning and health outcomes will enhance the

  1. The Proposed Use of Unmanned Aerial System Surrogate Research Aircraft for National Airspace System Integration Research

    NASA Technical Reports Server (NTRS)

    Howell, Charles T., III

    2011-01-01

    Research is needed to determine what procedures, aircraft sensors and other systems will be required to allow Unmanned Aerial Systems (UAS) to safely operate with manned aircraft in the National Airspace System (NAS). This paper explores the use of Unmanned Aerial System (UAS) Surrogate research aircraft to serve as platforms for UAS systems research, development, and flight testing. These aircraft would be manned with safety pilots and researchers that would allow for flight operations almost anywhere in the NAS without the need for a Federal Aviation Administration (FAA) Certificate of Authorization (COA). With pilot override capability, these UAS Surrogate aircraft would be controlled from ground stations like true UAS s. It would be possible to file and fly these UAS Surrogate aircraft in the NAS with normal traffic and they would be better platforms for real world UAS research and development over existing vehicles flying in restricted ranges or other sterilized airspace. These UAS surrogate aircraft could be outfitted with research systems as required such as computers, state sensors, video recording, data acquisition, data link, telemetry, instrumentation, and Automatic Dependent Surveillance-Broadcast (ADS-B). These surrogate aircraft could also be linked to onboard or ground based simulation facilities to further extend UAS research capabilities. Potential areas for UAS Surrogate research include the development, flight test and evaluation of sensors to aide in the process of air traffic "see-and-avoid". These and other sensors could be evaluated in real-time and compared with onboard human evaluation pilots. This paper examines the feasibility of using UAS Surrogate research aircraft as test platforms for a variety of UAS related research.

  2. Research on models of biological systems that can be integrated into mechatronic systems

    NASA Astrophysics Data System (ADS)

    Pop, P. P.; Pop-Vadean, A.; Barz, C.; Latinovic, T.; Chiver, O.

    2016-02-01

    The models of biological systems that we find on Earth can be the subject of research to develop a few mechatronic systems. Such models are offered by bees, ants, crows, cranes, etc. Article aims to investigate these models and their manifestations. Imitating this behavior and studied him offer ideas for develop models that can be integrated into mechatronic systems. They can be integrated into mechatronic system as algorithms for finding local optimum, to search, to detect an optimal way travel on a network, to find best decision, etc.

  3. Research on integrating sphere low-light level stress system

    NASA Astrophysics Data System (ADS)

    Yang, Donglin; Feng, Dawei

    2010-10-01

    Low-light level night vision device must be assessed by light stress reliability test in the design approval testing and production approval testing. The low-light level stress environment is the key to light stress reliability test on Low-light level night vision device. This paper studies the actual working environment of Low-light level night vision device from the aspects of night sky spectrum of nature light and illumination, and designs a low-light level stress system. The system consists of double-integrating-sphere light source, light stress automatic switching device, collimator, monitoring and control system for light stress. The system uses a total light source with radiation structure to improve the light efficiency, solve the question of light stress consistency, achieve a typical night-day simulation of the environment and the monitoring and control of the whole process.

  4. ICOS, Integrated Carbon Observing System, a Research Infrastructure to Integrate Greenhouse Gas observations in Europe

    NASA Astrophysics Data System (ADS)

    Ciais, P.; Paris, J.; Rivier, L.; Ceulemans, R.; Dolman, A. J.; Flaud, J.; Garrec, C.; Gerbig, C.; Grace, J.; Huertas, E.; Johannessen, T.; Jordan, A.; Levin, I.; Lindroth, A.; Loustau, D.; Papale, D.; Ramonet, M.; Valentini, R.; Vesala, T.; Kaukolehto, M.; Watson, A.

    2012-12-01

    The Integrated Carbon Observation System (ICOS) is a European Research infrastructure. ICOS's mission is to collect data for monitoring greenhouse gas fluxes over Europe and adjacent regions, and to provide the long-term observations required to quantify and to predict the behavior of the carbon cycle. ICOS builds upon the measurement networks and expertise developed under many European and national projects by a research community of more that 2000 researchers and students. ICOS received initial funding for the period 2008-2013 for the preparation of a Research Infrastructure hat will be operational in 2014 and run during the next 20 years a data collection for essential GHG variables including The presentation of ICOS will focus 1) on the mechanisms that have enabled the agencies / networks / governments to produce work products (data products, modeling products, and sensor acquired or human acquired measurements), and 2) on strategies to enable all identified user families, to take those products into assessments and analyses of European time varying maps GHG fluxes, including information on the attribution of these fluxes to underlying human and natural drivers and policy relevant information to improve GHG inventories at regional to national scale. These mechanisms take the form of adherence to technical standards (data, measurements, calibration/validation, modelling protocols), data policies, and governance mechanisms, which may prove complex when many different research councils and ministries are involved, as in the case of the ICOS preparation.

  5. Integrated earth system studies. Joint research efforts of global change

    SciTech Connect

    Rosswall, T.; Ojima, D.S.

    1995-06-01

    The physical, chemical and biological studies which have documented the changes to the Earth system and investigated the critical processes which couple the biosphere and the geosphere have increased our understanding of the natural variation in the Earth`s dynamics and of how human activities have modified these processes. This effort has been fundamental in furthering our understanding of what controls the Earth`s energy budget, global biogeochemistry including atmospheric composition of radiatively active gases and the hydrological cycle. This research has necessitated unprecedented international collaboration among various scientific disciplines and led to the development of major research programs like the World Climate Research Programme, the International Geosphere-Biosphere Programme, and the Human Dimensions of Global Environmental Change Programme. Through the Intergovernmental Panel on Climate Change a continuous assessment is carried out and provides the much needed bridge between science and policy making manifested in the development of a Framework Convention of Climate Change. The challenge now facing the global change science community is to maintain the interest in elucidating the functioning of the global system when political interest may move elsewhere. To understand the functioning of the Earth system is a daunting scientific challenge and a necessity for the necessary stewardship of planet Earth.

  6. Integrated web system of geospatial data services for climate research

    NASA Astrophysics Data System (ADS)

    Okladnikov, Igor; Gordov, Evgeny; Titov, Alexander

    2016-04-01

    Georeferenced datasets are currently actively used for modeling, interpretation and forecasting of climatic and ecosystem changes on different spatial and temporal scales. Due to inherent heterogeneity of environmental datasets as well as their huge size (up to tens terabytes for a single dataset) a special software supporting studies in the climate and environmental change areas is required. An approach for integrated analysis of georefernced climatological data sets based on combination of web and GIS technologies in the framework of spatial data infrastructure paradigm is presented. According to this approach a dedicated data-processing web system for integrated analysis of heterogeneous georeferenced climatological and meteorological data is being developed. It is based on Open Geospatial Consortium (OGC) standards and involves many modern solutions such as object-oriented programming model, modular composition, and JavaScript libraries based on GeoExt library, ExtJS Framework and OpenLayers software. This work is supported by the Ministry of Education and Science of the Russian Federation, Agreement #14.613.21.0037.

  7. An Integrated Data Management System for Marine Geoscience Research

    NASA Astrophysics Data System (ADS)

    Arko, R. A.; Carbotte, S. M.; Chayes, D. N.; Ryan, W. B.; Haxby, W. F.; Lehnert, K. A.; O'Hara, S.

    2004-12-01

    The National Science Foundation is currently supporting dedicated databases for the Ridge 2000, MARGINS, and U.S. Antarctic Programs. We are developing an integrated Marine Geoscience Data Management System (MG-DMS; www.marine-geo.org) which supports the full range of data types for all of these programs. Construction of a single system allows us to consolidate our hardware, software, and system administration infrastructure; work more efficiently; and focus greater resources on developing a unified metadata schema, controlled vocabularies, and interoperability with other databases. We have developed a Web-based client which offers forms-based search and download capability, and a JavaTM application (GeoMapApp; www.geomapapp.org) which offers map-based exploration of multiple data sets and the capability to create custom grids and images. The MG-DMS supports data from a wide variety of disciplines (biological, geological, and physical/chemical oceanographic); types (both physical samples and sensor data); spatial and temporal resolutions; and processing grades (from raw field data through derived products). Metadata records and controlled vocabularies are maintained locally in a central catalog, while the data files themselves are referenced as URLs and may reside in any partner repository. Our hierarchical metadata schema consists of Entries (typically a cruise, flight, or traverse); Dives (deployments of a daughter platform); Lines (survey transects); Stations (discrete survey locations, typically where physical samples are collected); Parameters (data types); and Arbitrary Digital Objects (data files). We are also developing a Lightweight Directory Access Protocol (LDAP)-based authentication system for proprietary data access and user profile management. We are pursuing data interoperability with partner repositories including the Ocean Floor Petrology Database (PetDB) at LDEO, Seismic Processed Data Center (SDC) at UTIG, Ocean Drilling Program Database (Janus

  8. Ontology-Based Data Integration between Clinical and Research Systems

    PubMed Central

    Mate, Sebastian; Köpcke, Felix; Toddenroth, Dennis; Martin, Marcus; Prokosch, Hans-Ulrich

    2015-01-01

    Data from the electronic medical record comprise numerous structured but uncoded ele-ments, which are not linked to standard terminologies. Reuse of such data for secondary research purposes has gained in importance recently. However, the identification of rele-vant data elements and the creation of database jobs for extraction, transformation and loading (ETL) are challenging: With current methods such as data warehousing, it is not feasible to efficiently maintain and reuse semantically complex data extraction and trans-formation routines. We present an ontology-supported approach to overcome this challenge by making use of abstraction: Instead of defining ETL procedures at the database level, we use ontologies to organize and describe the medical concepts of both the source system and the target system. Instead of using unique, specifically developed SQL statements or ETL jobs, we define declarative transformation rules within ontologies and illustrate how these constructs can then be used to automatically generate SQL code to perform the desired ETL procedures. This demonstrates how a suitable level of abstraction may not only aid the interpretation of clinical data, but can also foster the reutilization of methods for un-locking it. PMID:25588043

  9. NASA/Army Rotorcraft Technology. Volume 3: Systems Integration, Research Aircraft, and Industry

    NASA Technical Reports Server (NTRS)

    1988-01-01

    This is part 3 of the conference proceedings on rotorcraft technology. This volume is divided into areas on systems integration, research aircraft, and industry. Representative titles from each area are: system analysis in rotorcraft design, the past decade; rotorcraft flight research with emphasis on rotor systems; and an overview of key technology thrusts at Bell Helicopter Textron.

  10. Development and Application of an Integrated Approach toward NASA Airspace Systems Research

    NASA Technical Reports Server (NTRS)

    Barhydt, Richard; Fong, Robert K.; Abramson, Paul D.; Koenke, Ed

    2008-01-01

    The National Aeronautics and Space Administration's (NASA) Airspace Systems Program is contributing air traffic management research in support of the 2025 Next Generation Air Transportation System (NextGen). Contributions support research and development needs provided by the interagency Joint Planning and Development Office (JPDO). These needs generally call for integrated technical solutions that improve system-level performance and work effectively across multiple domains and planning time horizons. In response, the Airspace Systems Program is pursuing an integrated research approach and has adapted systems engineering best practices for application in a research environment. Systems engineering methods aim to enable researchers to methodically compare different technical approaches, consider system-level performance, and develop compatible solutions. Systems engineering activities are performed iteratively as the research matures. Products of this approach include a demand and needs analysis, system-level descriptions focusing on NASA research contributions, system assessment and design studies, and common systemlevel metrics, scenarios, and assumptions. Results from the first systems engineering iteration include a preliminary demand and needs analysis; a functional modeling tool; and initial system-level metrics, scenario characteristics, and assumptions. Demand and needs analysis results suggest that several advanced concepts can mitigate demand/capacity imbalances for NextGen, but fall short of enabling three-times current-day capacity at the nation s busiest airports and airspace. Current activities are focusing on standardizing metrics, scenarios, and assumptions, conducting system-level performance assessments of integrated research solutions, and exploring key system design interfaces.

  11. Integrating Systems Science and Community-Based Participatory Research to Achieve Health Equity.

    PubMed

    Frerichs, Leah; Lich, Kristen Hassmiller; Dave, Gaurav; Corbie-Smith, Giselle

    2016-02-01

    Unanswered questions about racial and socioeconomic health disparities may be addressed using community-based participatory research and systems science. Community-based participatory research is an orientation to research that prioritizes developing capacity, improving trust, and translating knowledge to action. Systems science provides research methods to study dynamic and interrelated forces that shape health disparities. Community-based participatory research and systems science are complementary, but their integration requires more research. We discuss paradigmatic, socioecological, capacity-building, colearning, and translational synergies that help advance progress toward health equity. PMID:26691110

  12. Integrated earth system studies. Joint research efforts of global change

    SciTech Connect

    McKeown, R.; Kittel, T.G.F.; Schimel, D.S.

    1995-06-01

    Analysis of changes to ecosystem C and N pools and fluxes from different natural and managed ecosystems across the continental US was conducted using the CENTURY ecosystem model. Ecosystem dynamics in responses to climate or land use changes do not immediately equilibrate to new environmental conditions. A variety of inherent properties of a biological system has built-in resistance to change in the environment. This includes pools of soil organic matter that resist changes in short-term climate signals, plant components related to ecosystem structure or biogeochemical properties. As climate changes, these pools serve as buffers against immediate changes in the biogeochemical response of the system. Our analysis indicate that certain of the managed ecosystems are more buffered to changes in the climate system than the natural systems; while others appear to be equally sensitive to these changes in rainfall and temperature.

  13. Building America Systems Integration Research Annual Report. FY 2012

    SciTech Connect

    Gestwick, Michael

    2013-05-01

    This Building America FY2012 Annual Report includes an overview of the Building America Program activities and the work completed by the National Renewable Energy Laboratory and the Building America industry consortia (the Building America teams). The annual report summarizes major technical accomplishments and progress towards U.S. Department of Energy Building Technologies Program's multi-year goal of developing the systems innovations that enable risk-free, cost effective, reliable and durable efficiency solutions that reduce energy use by 30%-50% in both new and existing homes.

  14. Building America Systems Integration Research Annual Report: FY 2012

    SciTech Connect

    Gestwick, M.

    2013-05-01

    This document is the Building America FY2012 Annual Report, which includes an overview of the Building America Program activities and the work completed by the National Renewable Energy Laboratory and the Building America industry consortia (the Building America teams). The annual report summarizes major technical accomplishments and progress towards U.S. Department of Energy Building Technologies Program's multi-year goal of developing the systems innovations that enable risk-free, cost effective, reliable and durable efficiency solutions that reduce energy use by 30%-50% in both new and existing homes.

  15. An integrated, semi-automated approach to thermochemical conversion research for sustainable farming systems

    Technology Transfer Automated Retrieval System (TEKTRAN)

    An integrated, semi-automated system is presented for the rapid and efficient testing and production of research-scale quantities of biochar. This biochar, produced from agricultural waste materials, can easily be incorporated in future sustainable livestock farming systems. These farming systems wi...

  16. Collecting, Integrating, and Disseminating Patient-Reported Outcomes for Research in a Learning Healthcare System

    PubMed Central

    Harle, Christopher A.; Lipori, Gloria; Hurley, Robert W.

    2016-01-01

    Introduction: Advances in health policy, research, and information technology have converged to increase the electronic collection and use of patient-reported outcomes (PROs). Therefore, it is important to share lessons learned in implementing PROs in research information systems. Case Description: The purpose of this case study is to describe a novel information system for electronic PROs and lessons learned in implementing that system to support research in an academic health center. The system incorporates freely available and commercial software and involves clinical and research workflows that support the collection, transformation, and research use of PRO data. The software and processes that comprise the system serve three main functions, (i) collecting electronic PROs in clinical care, (ii) integrating PRO data with non-patient generated clinical data, and (iii) disseminating data to researchers through the institution’s research informatics infrastructure, including the i2b2 (Informatics for Integrating Biology and the Bedside) system. Strategies: Our successful design and implementation was driven by three overarching strategies. First, we selected and implemented multiple interfaced technologies to support PRO collection, management, and research use. Second, we aimed to use standardized approaches to measuring PROs, sending PROs between systems, and disseminating PROs. Finally, we focused on using technologies and processes that aligned with existing clinical research information management strategies within our organization. Conclusion: These experiences and lessons may help future implementers and researchers enhance the scale and sustainable use of systems for research use of PROs. PMID:27563683

  17. Integrated Micro-Power System (IMPS) Development at NASA Glenn Research Center

    NASA Technical Reports Server (NTRS)

    Wilt, David; Hepp, Aloysius; Moran, Matt; Jenkins, Phillip; Scheiman, David; Raffaelle, Ryne

    2003-01-01

    Glenn Research Center (GRC) has a long history of energy related technology developments for large space related power systems, including photovoltaics, thermo-mechanical energy conversion, electrochemical energy storage. mechanical energy storage, power management and distribution and power system design. Recently, many of these technologies have begun to be adapted for small, distributed power system applications or Integrated Micro-Power Systems (IMPS). This paper will describe the IMPS component and system demonstration efforts to date.

  18. Development of the advanced life support Systems Integration Research Facility at NASA's Johnson Space Center

    NASA Technical Reports Server (NTRS)

    Tri, Terry O.; Thompson, Clifford D.

    1992-01-01

    Future NASA manned missions to the moon and Mars will require development of robust regenerative life support system technologies which offer high reliability and minimal resupply. To support the development of such systems, early ground-based test facilities will be required to demonstrate integrated, long-duration performance of candidate regenerative air revitalization, water recovery, and thermal management systems. The advanced life support Systems Integration Research Facility (SIRF) is one such test facility currently being developed at NASA's Johnson Space Center. The SIRF, when completed, will accommodate unmanned and subsequently manned integrated testing of advanced regenerative life support technologies at ambient and reduced atmospheric pressures. This paper provides an overview of the SIRF project, a top-level description of test facilities to support the project, conceptual illustrations of integrated test article configurations for each of the three SIRF systems, and a phased project schedule denoting projected activities and milestones through the next several years.

  19. Design of integrated autopilot/autothrottle for NASA TSRV airplane using integral LQG methodology. [transport systems research vehicle

    NASA Technical Reports Server (NTRS)

    Kaminer, Isaac; Benson, Russell A.

    1989-01-01

    An integrated autopilot/autothrottle control system has been developed for the NASA transport system research vehicle using a two-degree-of-freedom approach. Based on this approach, the feedback regulator was designed using an integral linear quadratic regulator design technique, which offers a systematic approach to satisfy desired feedback performance requirements and guarantees stability margins in both control and sensor loops. The resulting feedback controller was discretized and implemented using a delta coordinate concept, which allows for transient free controller switching by initializing all controller states to zero and provides a simple solution for dealing with throttle limiting cases.

  20. Large space antenna communications systems: Integrated Langley Research Center/Jet Propulsion Laboratory development activities. 2: Langley Research Center activities

    NASA Technical Reports Server (NTRS)

    Cambell, T. G.; Bailey, M. C.; Cockrell, C. R.; Beck, F. B.

    1983-01-01

    The electromagnetic analysis activities at the Langley Research Center are resulting in efficient and accurate analytical methods for predicting both far- and near-field radiation characteristics of large offset multiple-beam multiple-aperture mesh reflector antennas. The utilization of aperture integration augmented with Geometrical Theory of Diffraction in analyzing the large reflector antenna system is emphasized.

  1. Challenges in Integrating a Complex Systems Computer Simulation in Class: An Educational Design Research

    ERIC Educational Resources Information Center

    Loke, Swee-Kin; Al-Sallami, Hesham S.; Wright, Daniel F. B.; McDonald, Jenny; Jadhav, Sheetal; Duffull, Stephen B.

    2012-01-01

    Complex systems are typically difficult for students to understand and computer simulations offer a promising way forward. However, integrating such simulations into conventional classes presents numerous challenges. Framed within an educational design research, we studied the use of an in-house built simulation of the coagulation network in four…

  2. PathCase-SB: integrating data sources and providing tools for systems biology research

    PubMed Central

    2012-01-01

    Background Integration of metabolic pathways resources and metabolic network models, and deploying new tools on the integrated platform can help perform more effective and more efficient systems biology research on understanding the regulation of metabolic networks. Therefore, the tasks of (a) integrating under a single database environment regulatory metabolic networks and existing models, and (b) building tools to help with modeling and analysis are desirable and intellectually challenging computational tasks. Results PathCase Systems Biology (PathCase-SB) is built and released. This paper describes PathCase-SB user interfaces developed to date. The current PathCase-SB system provides a database-enabled framework and web-based computational tools towards facilitating the development of kinetic models for biological systems. PathCase-SB aims to integrate systems biology models data and metabolic network data of selected biological data sources on the web (currently, BioModels Database and KEGG, respectively), and to provide more powerful and/or new capabilities via the new web-based integrative framework. Conclusions Each of the current four PathCase-SB interfaces, namely, Browser, Visualization, Querying, and Simulation interfaces, have expanded and new capabilities as compared with the original data sources. PathCase-SB is already available on the web and being used by researchers across the globe. PMID:22697505

  3. Using Participatory Action Research to Design an Intervention Integrity System in the Urban Schools

    PubMed Central

    Gullan, Rebecca Lakin; Feinberg, Betsy E.; Freedman, Melanie A.; Jawad, Abbas; Leff, Stephen S.

    2010-01-01

    While integrity is often thought of as the degree to which a program is applied as intended, researchers have recently widened the lens to include not only monitoring of program content, but also evaluating the process by which interventions are implemented and the extent to which the intervention is received as intended. Further, a partnership-based approach has been identified to be as critical to facilitating appropriate and accurate monitoring and interpretation of intervention integrity in the cultural context. Building on these expanded definitions of intervention integrity, this study describes how an intervention monitoring system was developed through participatory research in the context of a classroom-based aggression prevention program for students in an inner-city elementary school. The system highlighted evaluation of the quality of intervention delivery and participant responsiveness. Factor analysis, descriptive statistics, and comparison to a less nuanced integrity monitoring system provided information on the informativeness of this new system. Preliminary investigation, however, suggested that future research is necessary to examine the extent to which differences in quality of implementation across classrooms predict clinically significant differences in program outcomes. PMID:20428475

  4. V/STOL Systems Research Aircraft: A Tool for Cockpit Integration

    NASA Technical Reports Server (NTRS)

    Stortz, Michael W.; ODonoghue, Dennis P.; Tiffany, Geary (Technical Monitor)

    1995-01-01

    The next generation ASTOVL aircraft will have a complicated propulsion System. The configuration choices include Direct Lift, Lift-Fan and Lift+Lift /Cruise but the aircraft must also have supersonic performance and low-observable characteristics. The propulsion system may have features such as flow blockers, vectoring nozzles and flow transfer schemes. The flight control system will necessarily fully integrate the aerodynamic surfaces and the propulsive elements. With a fully integrated, fly-by-wire flight/propulsion control system, the options for cockpit integration are interesting and varied. It is possible to decouple longitudinal and vertical responses allowing the pilot to close the loop on flight path and flight path acceleration directly. In the hover, the pilot can control the translational rate directly without having to stabilize the inner rate and attitude loops. The benefit of this approach, reduced workload and increased precision. has previously been demonstrated through several motion-based simulations. In order to prove the results in flight, the V/STOL System Research Aircraft (VSRA) was developed at the NASA Ames Research Center. The VSRA is the YAV-8B Prototype modified with a research flight control system using a series-parallel servo configuration in all the longitudinal degrees of freedom (including thrust and thrust vector angle) to provide an integrated flight and propulsion control system in a limited envelope. Development of the system has been completed and flight evaluations of the response types have been performed. In this paper we will discuss the development of the VSRA, the evolution of the flight path command and translational rate command response types and the Guest Pilot evaluations of the system. Pilot evaluation results will be used to draw conclusions regarding the suitability of the system to satisfy V/STOL requirements.

  5. V/STOL systems research aircraft: A tool for cockpit integration

    NASA Technical Reports Server (NTRS)

    Stortz, Michael W.; ODonoghue, Dennis P.

    1995-01-01

    The next generation ASTOVL aircraft will have a complicated propulsion system. The configuration choices include Direct Lift, Lift-Fan and Lift + Lift/Cruise but the aircraft must also have supersonic performance and low-observable characteristics. The propulsion system may have features such as flow blockers, vectoring nozzles and flow transfer schemes. The flight control system will necessarily fully integrate the aerodynamic surfaces and the propulsive elements. With a fully integrated, fly-by-wire flight/propulsion control system, the options for cockpit integration are interesting and varied. It is possible to de-couple longitudinal and vertical responses allowing the pilot to close the loop on flightpath and flightpath acceleration directly. In the hover, the pilot can control the translational rate directly without having to stabilize the inner rate and attitude loops. The benefit of this approach, reduced workload and increased precision, has previously been demonstrated through several motion-based simulations. In order to prove the results in flight, the V/STOL System Research Aircraft (VSRA) was developed at the NASA Ames Research Center. The VSRA is the YAV-8B Prototype modified with a research flight control system using a series-parallel servo configuration in all the longitudinal degrees of freedom (including thrust and thrust vector angle) to provide an integrated flight and propulsion control system in a limited envelope. Development of the system has been completed and flight evaluations of the response types have been performed. In this paper we will discuss the development of the VSRA, the evolution of the flightpath command and translational rate command response types and the Guest Pilot evaluations of the system. Pilot evaluation results are used to draw conclusions regarding the suitability of the system to satisfy V/STOL requirements.

  6. Integrating research infrastructures for solid Earth science in Europe: the European Plate Observing System

    NASA Astrophysics Data System (ADS)

    Cocco, M.; Giardini, D.; EPOS-PP Consortium

    2011-12-01

    The European Plate Observing System (EPOS) coordinates and integrates the research infrastructures in the European-Mediterranean region, to promote innovative approaches for a better understanding of the physical processes controlling earthquakes, volcanic eruptions, tsunamis as well as those driving tectonics and Earth surface dynamics. The EPOS 30-year plan aims at integrating the currently scattered, but highly advanced European facilities into one distributed, coherent multidisciplinary Research Infrastructure allowing sustainable long-term Earth science research strategies and an effective coordinated European-scale monitoring facility for solid Earth dynamics taking full advantage of new e-science opportunities. EPOS has been approved by ESFRI (the European Scientific Forum for Research Infrastructures) as one of the critical European Research Infrastructures, and the EPOS Preparatory Phase is supported by the European Commission FP7 program. The cooperation between EPOS and similar US infrastructures (i.e. Earthscope) will be ensured by dedicated NSF-EC funding. EPOS is integrating data from permanent national and regional geophysical monitoring networks (seismological, GPS), with the observations from "in-situ" observatories (volcano observatories, in-situ fault zone test sites) and temporary-monitoring and laboratory experiments through a cyber-infrastructure for data mining and processing, and facilities for data integration, archiving and exchange. The vision is to integrate these existing research infrastructures in order to increase the accessibility and usability of multidisciplinary data from monitoring networks, laboratory experiments and computational simulations enhancing worldwide interoperability in Earth Science by establishing a leading integrated European infrastructure and services. More recently the EPOS and the satellite Earth Observation communities are collaborating in order to promote the integration of data from in-situ monitoring

  7. Developing Data Elements for Research Information System in Health; a Starting Point for Systems Integration

    PubMed Central

    Ghorbani, NR; Ahmadi, M; Sadoughi, F; Ghanei, M

    2012-01-01

    Background: This study defines necessary data elements required for the research information system in the domain of health, and its level of accountability to national health research indicators from the experts’ perspective is being explored. Methods: This qualitative study was conducted based on comparative approach using the focus group method. Data were collected through 6 semi-structured group discussions held at the Undersecretary for Research and Technology, Ministry of Health and Medical Education, Tehran, Iran. For this study, 48 researchers were selected for the group discussions. All interviews and group discussions were recorded and transcribed. The Data analysis was performed simultaneously using Strauss and Corbin method. Results: Based on content analysis, the necessary data elements identified for the National Health Research Information System designed for all databases were the following: organizations, researchers, journals, articles, research projects and dissertations. Also, extracted from the focus group discussion were three main themes regarding data elements of these databases for the National Health Research Information System: 1) essential elements for each database 2) the system’s data elements accountability to the national indicators in the domain of health research and 3) recommendations in the direction of optimizing the data. Conclusions: The results obtained from this study can serve as a valuable source in designing research information system in the domain of health within the country and in the region as well. PMID:23641388

  8. The optical antenna system design research on earth integrative network laser link in the future

    NASA Astrophysics Data System (ADS)

    Liu, Xianzhu; Fu, Qiang; He, Jingyi

    2014-11-01

    Earth integrated information network can be real-time acquisition, transmission and processing the spatial information with the carrier based on space platforms, such as geostationary satellites or in low-orbit satellites, stratospheric balloons or unmanned and manned aircraft, etc. It is an essential infrastructure for China to constructed earth integrated information network. Earth integrated information network can not only support the highly dynamic and the real-time transmission of broadband down to earth observation, but the reliable transmission of the ultra remote and the large delay up to the deep space exploration, as well as provide services for the significant application of the ocean voyage, emergency rescue, navigation and positioning, air transportation, aerospace measurement or control and other fields.Thus the earth integrated information network can expand the human science, culture and productive activities to the space, ocean and even deep space, so it is the global research focus. The network of the laser communication link is an important component and the mean of communication in the earth integrated information network. Optimize the structure and design the system of the optical antenna is considered one of the difficulty key technologies for the space laser communication link network. Therefore, this paper presents an optical antenna system that it can be used in space laser communication link network.The antenna system was consisted by the plurality mirrors stitched with the rotational paraboloid as a substrate. The optical system structure of the multi-mirror stitched was simulated and emulated by the light tools software. Cassegrain form to be used in a relay optical system. The structural parameters of the relay optical system was optimized and designed by the optical design software of zemax. The results of the optimal design and simulation or emulation indicated that the antenna system had a good optical performance and a certain

  9. Supersonic Cruise Research 1979, part 2. [airframe structures and materials, systems integration, economic analysis

    NASA Technical Reports Server (NTRS)

    1980-01-01

    Advances in airframe structure and materials technology for supersonic cruise aircraft are reported with emphasis on titanium and composite structures. The operation of the Concorde is examined as a baseline for projections into the future. A market survey of U.S. passenger attitudes and preferences, the impact of advanced air transport technology and the integration of systems for the advanced SST and for a smaller research/business jet vehicle are also discussed.

  10. Systematic calibration of an integrated x-ray and optical tomography system for preclinical radiation research

    PubMed Central

    Yang, Yidong; Wang, Ken Kang-Hsin; Eslami, Sohrab; Iordachita, Iulian I.; Patterson, Michael S.; Wong, John W.

    2015-01-01

    Purpose: The cone beam computed tomography (CBCT) guided small animal radiation research platform (SARRP) has been developed for focal tumor irradiation, allowing laboratory researchers to test basic biological hypotheses that can modify radiotherapy outcomes in ways that were not feasible previously. CBCT provides excellent bone to soft tissue contrast, but is incapable of differentiating tumors from surrounding soft tissue. Bioluminescence tomography (BLT), in contrast, allows direct visualization of even subpalpable tumors and quantitative evaluation of tumor response. Integration of BLT with CBCT offers complementary image information, with CBCT delineating anatomic structures and BLT differentiating luminescent tumors. This study is to develop a systematic method to calibrate an integrated CBCT and BLT imaging system which can be adopted onboard the SARRP to guide focal tumor irradiation. Methods: The integrated imaging system consists of CBCT, diffuse optical tomography (DOT), and BLT. The anatomy acquired from CBCT and optical properties acquired from DOT serve as a priori information for the subsequent BLT reconstruction. Phantoms were designed and procedures were developed to calibrate the CBCT, DOT/BLT, and the entire integrated system. Geometrical calibration was performed to calibrate the CBCT system. Flat field correction was performed to correct the nonuniform response of the optical imaging system. Absolute emittance calibration was performed to convert the camera readout to the emittance at the phantom or animal surface, which enabled the direct reconstruction of the bioluminescence source strength. Phantom and mouse imaging were performed to validate the calibration. Results: All calibration procedures were successfully performed. Both CBCT of a thin wire and a euthanized mouse revealed no spatial artifact, validating the accuracy of the CBCT calibration. The absolute emittance calibration was validated with a 650 nm laser source, resulting in a 3

  11. Systematic calibration of an integrated x-ray and optical tomography system for preclinical radiation research

    SciTech Connect

    Yang, Yidong; Wang, Ken Kang-Hsin; Wong, John W.; Eslami, Sohrab; Iordachita, Iulian I.; Patterson, Michael S.

    2015-04-15

    Purpose: The cone beam computed tomography (CBCT) guided small animal radiation research platform (SARRP) has been developed for focal tumor irradiation, allowing laboratory researchers to test basic biological hypotheses that can modify radiotherapy outcomes in ways that were not feasible previously. CBCT provides excellent bone to soft tissue contrast, but is incapable of differentiating tumors from surrounding soft tissue. Bioluminescence tomography (BLT), in contrast, allows direct visualization of even subpalpable tumors and quantitative evaluation of tumor response. Integration of BLT with CBCT offers complementary image information, with CBCT delineating anatomic structures and BLT differentiating luminescent tumors. This study is to develop a systematic method to calibrate an integrated CBCT and BLT imaging system which can be adopted onboard the SARRP to guide focal tumor irradiation. Methods: The integrated imaging system consists of CBCT, diffuse optical tomography (DOT), and BLT. The anatomy acquired from CBCT and optical properties acquired from DOT serve as a priori information for the subsequent BLT reconstruction. Phantoms were designed and procedures were developed to calibrate the CBCT, DOT/BLT, and the entire integrated system. Geometrical calibration was performed to calibrate the CBCT system. Flat field correction was performed to correct the nonuniform response of the optical imaging system. Absolute emittance calibration was performed to convert the camera readout to the emittance at the phantom or animal surface, which enabled the direct reconstruction of the bioluminescence source strength. Phantom and mouse imaging were performed to validate the calibration. Results: All calibration procedures were successfully performed. Both CBCT of a thin wire and a euthanized mouse revealed no spatial artifact, validating the accuracy of the CBCT calibration. The absolute emittance calibration was validated with a 650 nm laser source, resulting in a 3

  12. The Integrity of Research

    ERIC Educational Resources Information Center

    Axman, Linnea; Boren, Denise

    2010-01-01

    This text is the foundation from which a distinguished lecture was developed focusing on the necessity for research in healthcare carried out with attention to issues of integrity, the hallmark of all commendable research. A cautionary historical review of research misconduct and related topics is provided. Research within a cultural context and…

  13. Avionics systems integration technology

    NASA Technical Reports Server (NTRS)

    Stech, George; Williams, James R.

    1988-01-01

    A very dramatic and continuing explosion in digital electronics technology has been taking place in the last decade. The prudent and timely application of this technology will provide Army aviation the capability to prevail against a numerically superior enemy threat. The Army and NASA have exploited this technology explosion in the development and application of avionics systems integration technology for new and future aviation systems. A few selected Army avionics integration technology base efforts are discussed. Also discussed is the Avionics Integration Research Laboratory (AIRLAB) that NASA has established at Langley for research into the integration and validation of avionics systems, and evaluation of advanced technology in a total systems context.

  14. An Integrated X-Ray/Optical Tomography System for Pre-clinical Radiation Research

    PubMed Central

    Eslami, S.; Yang, Y.; Wong, J.; Patterson, M. S.; Iordachita, I.

    2013-01-01

    The current Small Animal Radiation Research Platform (SARRP) is poor for localizing small soft tissue targets for irradiation or tumor models growing in a soft tissue environment. Therefore, an imaging method complementary to x-ray CT is required to localize the soft tissue target’s Center of Mass (CoM) to within 1 mm. In this paper, we report the development of an integrated x-ray/bioluminescence imaging/tomography (BLI/BLT) system to provide a pre-clinical, high resolution irradiation system. This system can be used to study radiation effects in small animals under the conebeam computed tomography (CBCT) imaging guidance by adding the bioluminescence imaging (BLI) system as a standalone system which can also be docked onto the SARRP. The proposed system integrates two robotic rotating stages and an x-ray source rated at maximum 130 kVp and having a small variable focal spot. A high performance and low noise CCD camera mounted in a light-tight housing along with an optical filter assembly is used for multi-wavelength BL tomography. A three-mirror arrangement is implemented to eliminate the need of rotating the CCD camera for acquiring multiple views. The mirror system is attached to a motorized stage to capture images in angles between 0–90° (for the standalone system). Camera and CBCT calibration are accomplished. PMID:25745539

  15. The Digital Astronaut: An integrated modeling and database system for space biomedical research and operations

    NASA Astrophysics Data System (ADS)

    White, Ronald J.; McPhee, Jancy C.

    2007-02-01

    The Digital Astronaut is an integrated, modular modeling and database system that will support space biomedical research and operations in a variety of fundamental ways. This system will enable the identification and meaningful interpretation of the medical and physiological research required for human space exploration, a determination of the effectiveness of specific individual human countermeasures in reducing risk and meeting health and performance goals on challenging exploration missions and an evaluation of the appropriateness of various medical interventions during mission emergencies, accidents and illnesses. Such a computer-based, decision support system will enable the construction, validation and utilization of important predictive simulations of the responses of the whole human body to the types of stresses experienced during space flight and low-gravity environments. These simulations will be essential for direct, real-time analysis and maintenance of astronaut health and performance capabilities. The Digital Astronaut will collect and integrate past and current human data across many physiological disciplines and simulations into an operationally useful form that will not only summarize knowledge in a convenient and novel way but also reveal gaps that must be filled via new research in order to effectively ameliorate biomedical risks. Initial phases of system development will focus on simulating ground-based analog systems that are just beginning to collect multidisciplinary data in a standardized way (e.g., the International Multidisciplinary Artificial Gravity Project). During later phases, the focus will shift to development and planning for missions and to exploration mission operations. Then, the Digital Astronaut system will enable evaluation of the effectiveness of multiple, simultaneously applied countermeasures (a task made difficult by the many-system physiological effects of individual countermeasures) and allow for the prescription of

  16. Vehicle Integrated Propulsion Research Tests

    NASA Technical Reports Server (NTRS)

    Lekki, John D.; Hunter, Gary W.; Simon, Don; Meredith, Roger; Wrbanek, John; Woike, Mark; Tokars, Roger; Guffanti, Marianne; Lyall, Eric

    2013-01-01

    Overview of the Vehicle Integrated Propulsion Research Tests in the Vehicle Systems Safety Technologies project. This overview covers highlights of the completed VIPR I and VIPR II tests and also covers plans for the VIPR III test.

  17. Creation of Integrated System of Cosmonauts Sanitary-Hygienic Supply: Researches, Problems and Prospects

    NASA Astrophysics Data System (ADS)

    Shumilina, I.; Krivobok, S.; Shumilina, G.

    The necessity of Integrated System creation for cosmonauts Sanitary - Hygienic Supply has appeared at realization of joint flights on the International Space Station (ISS). Russian hygiene means manufactured and tested in the long space flights conditions and personal hygiene means of foreign manufacture, which were developed without chamber experiments conditions, are mean to use for Integrated System. The realization of Sanitary - Hygienic Water (SHW) regeneration is supposed for water circulation. The researches directed on equipment creation for clothing washing and clothing drying were carried out for the purposes of goods turnover optimization on ISS The variants of possible realization of water procedures (shower-bath, face washing) are studied. New and essentially date are received for an estimation of efficiency of various ways of cosmonauts Sanitary - Hygienic Supply, including results of tests for new generation regeneration SHW systems with Nanofiltration unit on various kinds real SHW. The improvement of washing-up liquids, individual selection of a complex of personal hygiene means with the man skin condition registration allows to raise of preventive measures use efficiency directed on prevention of adverse skin changes and skin diseases. The analysis of the equipment and methods for clothing washing and clothing drying for conditions of long space flight are carried out. The experimental data on textile materials drying are received. The investigations covered a wide range of issues associated with Sanitary - Hygienic Supply Integrated System including Personal Hygiene complex (items and techniques), ways of Sanitary - Hygienic Supply realization, methods of wastewater regeneration. The results of researches are especially urgent for cosmonauts Sanitary - Hygienic Supply System creation for long space flights, in particular, "Mars" flights at impossibility of updating of water stock, clothing stock etc.

  18. Leading Integrated Health and Social Care Systems: Perspectives from Research and Practice.

    PubMed

    Evans, Jenna M; Daub, Stacey; Goldhar, Jodeme; Wojtak, Anne; Purbhoo, Dipti

    2016-01-01

    As the research evidence on integrated care has evolved over the past two decades, so too has the critical role leaders have for the implementation, effectiveness and sustainability of integrated care. This paper explores what it means to be an effective leader of integrated care initiatives by drawing from the experiences of a leadership team in implementing an award-winning integrated care program in Toronto, Canada. Lessons learned are described and assessed against existing theory and research to identify which skills and behaviours facilitate effective leadership of integrated care initiatives. PMID:27009705

  19. Note: A novel integrated microforce measurement system for plane-plane contact research

    NASA Astrophysics Data System (ADS)

    Dong, W.; Rostoucher, D.; Gauthier, M.

    2010-11-01

    The evaluation of plane-plane contact force has become a big issue in micro-/nano research, for example in microassembly. However with the lack of effective experimental equipments, the research on plane-plane contact has been limited to theoretical formulations or virtual simulation. In this paper, a microforce sensor and precision parallel robot integrated system is proposed for the microforce measurement of plane-plane contact. In the proposed system, the two objects are fixed on the parallel robot end-platform and the microforce sensor probe tip, respectively, and the high precision robot system is employed to provide six degree-of-freedom motions between both objects. So it is convenient for the microforce measurement between the planar objects with different orientations. As a significant application, the proposed system is utilized for measurements of pull-off force between planar objects, in which the validation of the system is demonstrated in practice. The proposed microforce measurement system is generic, which can be extended to a variety of microforce measurements in plane-plane contact.

  20. Searching biosignal databases by content and context: Research Oriented Integration System for ECG Signals (ROISES).

    PubMed

    Kokkinaki, Alexandra; Chouvarda, Ioanna; Maglaveras, Nicos

    2012-11-01

    Technological advances in textile, biosensor and electrocardiography domain induced the wide spread use of bio-signal acquisition devices leading to the generation of massive bio-signal datasets. Among the most popular bio-signals, electrocardiogram (ECG) possesses the longest tradition in bio-signal monitoring and recording, being a strong and relatively robust signal. As research resources are fostered, research community promotes the need to extract new knowledge from bio-signals towards the adoption of new medical procedures. However, integrated access, query and management of ECGs are impeded by the diversity and heterogeneity of bio-signal storage data formats. In this scope, the proposed work introduces a new methodology for the unified access to bio-signal databases and the accompanying metadata. It allows decoupling information retrieval from actual underlying datasource structures and enables transparent content and context based searching from multiple data resources. Our approach is based on the definition of an interactive global ontology which manipulates the similarities and the differences of the underlying sources to either establish similarity mappings or enrich its terminological structure. We also introduce ROISES (Research Oriented Integration System for ECG Signals), for the definition of complex content based queries against the diverse bio-signal data sources. PMID:21397354

  1. Integrated testing and verification system for research flight software design document

    NASA Technical Reports Server (NTRS)

    Taylor, R. N.; Merilatt, R. L.; Osterweil, L. J.

    1979-01-01

    The NASA Langley Research Center is developing the MUST (Multipurpose User-oriented Software Technology) program to cut the cost of producing research flight software through a system of software support tools. The HAL/S language is the primary subject of the design. Boeing Computer Services Company (BCS) has designed an integrated verification and testing capability as part of MUST. Documentation, verification and test options are provided with special attention on real time, multiprocessing issues. The needs of the entire software production cycle have been considered, with effective management and reduced lifecycle costs as foremost goals. Capabilities have been included in the design for static detection of data flow anomalies involving communicating concurrent processes. Some types of ill formed process synchronization and deadlock also are detected statically.

  2. Gaseous Monitoring for the Integrated Life Support System at Langley Research Center

    NASA Technical Reports Server (NTRS)

    Mason, E. E.; Wilson, Thomas O.

    1967-01-01

    The Integrated Life Support System was conceived to study the problems of integrating regenerative equipment designed to operate in a negligible gravitational field. It is the first to fully integrate the three major contributors to atmospheric contamination: man, machine, and materials.

  3. A Survey of Applications and Research in Integrated Design Systems Technology

    NASA Technical Reports Server (NTRS)

    1998-01-01

    The initial part of the study was begun with a combination of literature searches, World Wide Web searches, and contacts with individuals and companies who were known to members of our team to have an interest in topics that seemed to be related to our study. There is a long list of such topics, such as concurrent engineering, design for manufacture, life-cycle engineering, systems engineering, systems integration, systems design, design systems, integrated product and process approaches, enterprise integration, integrated product realization, and similar terms. These all capture, at least in part, the flavor of what we describe here as integrated design systems. An inhibiting factor in this inquiry was the absence of agreed terminology for the study of integrated design systems. It is common for the term to be applied to what are essentially augmented Computer-Aided Design (CAD) systems, which are integrated only to the extent that agreements have been reached to attach proprietary extensions to proprietary CAD programs. It is also common for some to use the term integrated design systems to mean a system that applies only, or mainly, to the design phase of a product life cycle. It is likewise common for many of the terms listed earlier to be used as synonyms for integrated design systems. We tried to avoid this ambiguity by adopting the definition of integrated design systems that is implied in the introductory notes that we provided to our contacts, cited earlier. We thus arrived at this definition: Integrated Design Systems refers to the integration of the different tools and processes that comprise the engineering, of complex systems. It takes a broad view of the engineering of systems, to include consideration of the entire product realization process and the product life cycle. An important aspect of integrated design systems is the extent to which they integrate existing, "islands of automation" into a comprehensive design and product realization

  4. toxoMine: an integrated omics data warehouse for Toxoplasma gondii systems biology research.

    PubMed

    Rhee, David B; Croken, Matthew McKnight; Shieh, Kevin R; Sullivan, Julie; Micklem, Gos; Kim, Kami; Golden, Aaron

    2015-01-01

    Toxoplasma gondii (T. gondii) is an obligate intracellular parasite that must monitor for changes in the host environment and respond accordingly; however, it is still not fully known which genetic or epigenetic factors are involved in regulating virulence traits of T. gondii. There are on-going efforts to elucidate the mechanisms regulating the stage transition process via the application of high-throughput epigenomics, genomics and proteomics techniques. Given the range of experimental conditions and the typical yield from such high-throughput techniques, a new challenge arises: how to effectively collect, organize and disseminate the generated data for subsequent data analysis. Here, we describe toxoMine, which provides a powerful interface to support sophisticated integrative exploration of high-throughput experimental data and metadata, providing researchers with a more tractable means toward understanding how genetic and/or epigenetic factors play a coordinated role in determining pathogenicity of T. gondii. As a data warehouse, toxoMine allows integration of high-throughput data sets with public T. gondii data. toxoMine is also able to execute complex queries involving multiple data sets with straightforward user interaction. Furthermore, toxoMine allows users to define their own parameters during the search process that gives users near-limitless search and query capabilities. The interoperability feature also allows users to query and examine data available in other InterMine systems, which would effectively augment the search scope beyond what is available to toxoMine. toxoMine complements the major community database ToxoDB by providing a data warehouse that enables more extensive integrative studies for T. gondii. Given all these factors, we believe it will become an indispensable resource to the greater infectious disease research community. PMID:26130662

  5. toxoMine: an integrated omics data warehouse for Toxoplasma gondii systems biology research

    PubMed Central

    Rhee, David B.; Croken, Matthew McKnight; Shieh, Kevin R.; Sullivan, Julie; Micklem, Gos; Kim, Kami; Golden, Aaron

    2015-01-01

    Toxoplasma gondii (T. gondii) is an obligate intracellular parasite that must monitor for changes in the host environment and respond accordingly; however, it is still not fully known which genetic or epigenetic factors are involved in regulating virulence traits of T. gondii. There are on-going efforts to elucidate the mechanisms regulating the stage transition process via the application of high-throughput epigenomics, genomics and proteomics techniques. Given the range of experimental conditions and the typical yield from such high-throughput techniques, a new challenge arises: how to effectively collect, organize and disseminate the generated data for subsequent data analysis. Here, we describe toxoMine, which provides a powerful interface to support sophisticated integrative exploration of high-throughput experimental data and metadata, providing researchers with a more tractable means toward understanding how genetic and/or epigenetic factors play a coordinated role in determining pathogenicity of T. gondii. As a data warehouse, toxoMine allows integration of high-throughput data sets with public T. gondii data. toxoMine is also able to execute complex queries involving multiple data sets with straightforward user interaction. Furthermore, toxoMine allows users to define their own parameters during the search process that gives users near-limitless search and query capabilities. The interoperability feature also allows users to query and examine data available in other InterMine systems, which would effectively augment the search scope beyond what is available to toxoMine. toxoMine complements the major community database ToxoDB by providing a data warehouse that enables more extensive integrative studies for T. gondii. Given all these factors, we believe it will become an indispensable resource to the greater infectious disease research community. Database URL: http://toxomine.org PMID:26130662

  6. Internet-based profiler system as integrative framework to support translational research

    PubMed Central

    Kim, Robert; Demichelis, Francesca; Tang, Jeffery; Riva, Alberto; Shen, Ronglai; Gibbs, Doug F; Mahavishno, Vasudeva; Chinnaiyan, Arul M; Rubin, Mark A

    2005-01-01

    Background Translational research requires taking basic science observations and developing them into clinically useful tests and therapeutics. We have developed a process to develop molecular biomarkers for diagnosis and prognosis by integrating tissue microarray (TMA) technology and an internet-database tool, Profiler. TMA technology allows investigators to study hundreds of patient samples on a single glass slide resulting in the conservation of tissue and the reduction in inter-experimental variability. The Profiler system allows investigator to reliably track, store, and evaluate TMA experiments. Here within we describe the process that has evolved through an empirical basis over the past 5 years at two academic institutions. Results The generic design of this system makes it compatible with multiple organ system (e.g., prostate, breast, lung, renal, and hematopoietic system,). Studies and folders are restricted to authorized users as required. Over the past 5 years, investigators at 2 academic institutions have scanned 656 TMA experiments and collected 63,311 digital images of these tissue samples. 68 pathologists from 12 major user groups have accessed the system. Two groups directly link clinical data from over 500 patients for immediate access and the remaining groups choose to maintain clinical and pathology data on separate systems. Profiler currently has 170 K data points such as staining intensity, tumor grade, and nuclear size. Due to the relational database structure, analysis can be easily performed on single or multiple TMA experimental results. The TMA module of Profiler can maintain images acquired from multiple systems. Conclusion We have developed a robust process to develop molecular biomarkers using TMA technology and an internet-based database system to track all steps of this process. This system is extendable to other types of molecular data as separate modules and is freely available to academic institutions for licensing. PMID:16364175

  7. Designing a Model for Integration of Information and Communication Technologies (ICTs) in the Iranian Agricultural Research System

    ERIC Educational Resources Information Center

    Sharifzadeh, Aboulqasem; Abdollahzadeh, Gholam Hossein; Sharifi, Mahnoosh

    2009-01-01

    Capacity Development is needed in the Iranian Agricultural System. Integrating Information and Communication Technologies (ICTs) in the agricultural research system is an appropriate capacity development mechanism. The appropriate application of ICTs and information such as a National Agricultural Information System requires a systemically…

  8. The Quality of Disabled Students' School Integration : A Research Experience in the Italian State School System

    ERIC Educational Resources Information Center

    Reversi, Stefania; Langher, Viviana; Crisafulli, Valeria; Ferri, Rosa

    2007-01-01

    The aim of this study was to assess the quality of school integration for disabled students in the Italian state school system, according to two criteria: the mainstream and the special teachers' point of view concerning the disabled students' social and syllabus integration, and the sense of loneliness of the disabled students in their classes.…

  9. Propulsion System Airframe Integration Issues and Aerodynamic Database Development for the Hyper-X Flight Research Vehicle

    NASA Technical Reports Server (NTRS)

    Engelund, Walter C.; Holland, Scott D.; Cockrell, Charles E., Jr.; Bittner, Robert D.

    1999-01-01

    NASA's Hyper-X Research Vehicle will provide a unique opportunity to obtain data on an operational airframe integrated scramjet propulsion system at true flight conditions. The airframe integrated nature of the scramjet engine with the Hyper-X vehicle results in a strong coupling effect between the propulsion system operation and the airframe s basic aerodynamic characteristics. Comments on general airframe integrated scramjet propulsion system effects on vehicle aerodynamic performance, stability, and control are provided, followed by examples specific to the Hyper-X research vehicle. An overview is provided of the current activities associated with the development of the Hyper-X aerodynamic database, including wind tunnel test activities and parallel CFD analysis efforts. A brief summary of the Hyper-X aerodynamic characteristics is provided, including the direct and indirect effects of the airframe integrated scramjet propulsion system operation on the basic airframe stability and control characteristics.

  10. Verifying Data Integrity of Electronically Scanned Pressure Systems at the NASA Glenn Research Center

    NASA Technical Reports Server (NTRS)

    Panek, Joseph W.

    2001-01-01

    The proper operation of the Electronically Scanned Pressure (ESP) System critical to accomplish the following goals: acquisition of highly accurate pressure data for the development of aerospace and commercial aviation systems and continuous confirmation of data quality to avoid costly, unplanned, repeat wind tunnel or turbine testing. Standard automated setup and checkout routines are necessary to accomplish these goals. Data verification and integrity checks occur at three distinct stages, pretest pressure tubing and system checkouts, daily system validation and in-test confirmation of critical system parameters. This paper will give an overview of the existing hardware, software and methods used to validate data integrity.

  11. Advanced Stirling Convertor Dual Convertor Controller Testing at NASA Glenn Research Center in the Radioisotope Power Systems System Integration Laboratory

    NASA Technical Reports Server (NTRS)

    Dugala, Gina M.; Taylor, Linda M.; Bell, Mark E.; Dolce, James L.; Fraeman, Martin; Frankford, David P.

    2015-01-01

    NASA Glenn Research Center developed a nonnuclear representation of a Radioisotope Power System (RPS) consisting of a pair of Advanced Stirling Convertors (ASCs), Dual Convertor Controller (DCC) EMs (engineering models) 2 and 3, and associated support equipment, which were tested in the Radioisotope Power Systems System Integration Laboratory (RSIL). The DCC was designed by the Johns Hopkins University Applied Physics Laboratory (JHU/APL) to actively control a pair of ASCs. The first phase of testing included a Dual Advanced Stirling Convertor Simulator (DASCS), which was developed by JHU/APL and simulates the operation and electrical behavior of a pair of ASCs in real time via a combination of hardware and software. RSIL provides insight into the electrical interactions between a representative radioisotope power generator, its associated control schemes, and realistic electric system loads. The first phase of integration testing included the following spacecraft bus configurations: capacitive, battery, and super-capacitor. A load profile, created based on data from several missions, tested the RPS's and RSIL's ability to maintain operation during load demands above and below the power provided by the RPS. The integration testing also confirmed the DCC's ability to disconnect from the spacecraft when the bus voltage dipped below 22 volts or exceeded 36 volts. Once operation was verified with the DASCS, the tests were repeated with actual operating ASCs. The goal of this integration testing was to verify operation of the DCC when connected to a spacecraft and to verify the functionality of the newly designed RSIL. The results of these tests are presented in this paper.

  12. Advanced Stirling Convertor Dual Convertor Controller Testing at NASA Glenn Research Center in the Radioisotope Power Systems System Integration Laboratory

    NASA Technical Reports Server (NTRS)

    Dugala, Gina M.; Taylor, Linda M.; Bell, Mark E.; Dolce, James L.; Fraeman, Martin; Frankford, David P.

    2015-01-01

    NASA Glenn Research Center (GRC) developed a non-nuclear representation of a Radioisotope Power System (RPS) consisting of a pair of Advanced Stirling Convertors (ASC), a Dual Convertor Controller (DCC) EM (engineering model) 2 & 3, and associated support equipment, which were tested in the Radioisotope Power Systems System Integration Laboratory (RSIL). The DCC was designed by the Johns Hopkins University/Applied Physics Laboratory (JHU/APL) to actively control a pair of Advanced Stirling Convertors (ASC). The first phase of testing included a Dual Advanced Stirling Convertor Simulator (DASCS) which was developed by JHU/APL and simulates the operation and electrical behavior of a pair of ASC's in real time via a combination of hardware and software. RSIL provides insight into the electrical interactions between a representative radioisotope power generator, its associated control schemes, and realistic electric system loads. The first phase of integration testing included the following spacecraft bus configurations: capacitive, battery, and supercapacitor. A load profile, created based on data from several missions, tested the RPS and RSIL ability to maintain operation during load demands above and below the power provided by the RPS. The integration testing also confirmed the DCC's ability to disconnect from the spacecraft when the bus voltage dipped below 22 V or exceeded 36 V. Once operation was verified with the DASCS, the tests were repeated with actual operating ASC's. The goal of this integration testing was to verify operation of the DCC when connected to a spacecraft and to verify the functionality of the newly designed RSIL. The results of these tests are presented in this paper.

  13. Evaluating the informatics for integrating biology and the bedside system for clinical research

    PubMed Central

    2009-01-01

    Background Selecting patient cohorts is a critical, iterative, and often time-consuming aspect of studies involving human subjects; informatics tools for helping streamline the process have been identified as important infrastructure components for enabling clinical and translational research. We describe the evaluation of a free and open source cohort selection tool from the Informatics for Integrating Biology and the Bedside (i2b2) group: the i2b2 hive. Methods Our evaluation included the usability and functionality of the i2b2 hive using several real world examples of research data requests received electronically at the University of Utah Health Sciences Center between 2006 - 2008. The hive server component and the visual query tool application were evaluated for their suitability as a cohort selection tool on the basis of the types of data elements requested, as well as the effort required to fulfill each research data request using the i2b2 hive alone. Results We found the i2b2 hive to be suitable for obtaining estimates of cohort sizes and generating research cohorts based on simple inclusion/exclusion criteria, which consisted of about 44% of the clinical research data requests sampled at our institution. Data requests that relied on post-coordinated clinical concepts, aggregate values of clinical findings, or temporal conditions in their inclusion/exclusion criteria could not be fulfilled using the i2b2 hive alone, and required one or more intermediate data steps in the form of pre- or post-processing, modifications to the hive metadata, etc. Conclusion The i2b2 hive was found to be a useful cohort-selection tool for fulfilling common types of requests for research data, and especially in the estimation of initial cohort sizes. For another institution that might want to use the i2b2 hive for clinical research, we recommend that the institution would need to have structured, coded clinical data and metadata available that can be transformed to fit the

  14. Making the Case for New Research to Support the Integration of Small Unmanned Aircraft Systems into the National Airspace System

    NASA Technical Reports Server (NTRS)

    McAdaragh, Raymon M.; Comstock, James R., Jr.; Ghatas, Rania W.; Burdette, Daniel W.; Trujillo, Anna C.

    2014-01-01

    This paper describes the current state of sUAS regulation, their technical capabilities and the latest technologies that will allow for sUAS NAS integration. The research that is needed to demonstrate sUAS NAS integration capability is identified, and recommendations for conducting this necessary research are suggested.

  15. Research on application information system integration platform in medicine manufacturing enterprise.

    PubMed

    Deng, Wu; Zhao, Huimin; Zou, Li; Li, Yuanyuan; Li, Zhengguang

    2012-08-01

    Computer and information technology popularizes in the medicine manufacturing enterprise for its potentials in working efficiency and service quality. In allusion to the explosive data and information of application system in current medicine manufacturing enterprise, we desire to propose a novel application information system integration platform in medicine manufacturing enterprise, which based on a combination of RFID technology and SOA, to implement information sharing and alternation. This method exploits the application integration platform across service interface layer to invoke the RFID middleware. The loose coupling in integration solution is realized by Web services. The key techniques in RFID event components and expanded role-based security access mechanism are studied in detail. Finally, a case study is implemented and tested to evidence our understanding on application system integration platform in medicine manufacturing enterprise. PMID:21479623

  16. MUST - An integrated system of support tools for research flight software engineering. [Multipurpose User-oriented Software Technology

    NASA Technical Reports Server (NTRS)

    Straeter, T. A.; Foudriat, E. C.; Will, R. W.

    1977-01-01

    The objectives of NASA's MUST (Multipurpose User-oriented Software Technology) program at Langley Research Center are to cut the cost of producing software which effectively utilizes digital systems for flight research. These objectives will be accomplished by providing an integrated system of support software tools for use throughout the research flight software development process. A description of the overall MUST program and its progress toward the release of a first MUST system will be presented. This release includes: a special interactive user interface, a library of subroutines, assemblers, a compiler, automatic documentation tools, and a test and simulation system.

  17. Integration of lessons from recent research for “Earth to Mars” life support systems

    NASA Astrophysics Data System (ADS)

    Nelson, M.; Dempster, W. F.; Allen, J. P.

    Development of reliable and robust strategies for long-term life support for planetary exploration must be built from real-time experimentation to verify and improve system components. Also critical is incorporating a range of viable options to handle potential short-term life system imbalances. This paper revisits some of the conceptual framework for a Mars base prototype which has been developed by the authors along with others previously advanced ("Mars on Earth ®") in the light of three years of experimentation in the Laboratory Biosphere, further investigation of system alternatives and the advent of other innovative engineering and agri-ecosystem approaches. Several experiments with candidate space agriculture crops have demonstrated the higher productivity possible with elevated light levels and improved environmental controls. For example, crops of sweet potatoes exceeded original Mars base prototype projections by an average of 46% (53% for best crop) ultradwarf (Apogee) wheat by 9% (23% for best crop), pinto bean by 13% (31% for best crop). These production levels, although they may be increased with further optimization of lighting regimes, environmental parameters, crop density etc. offer evidence that a soil-based system can be as productive as the hydroponic systems which have dominated space life support scenarios and research. But soil also offers distinct advantages: the capability to be created on the Moon or Mars using in situ space resources, reduces long-term reliance on consumables and imported resources, and more readily recycling and incorporating crew and crop waste products. In addition, a living soil contains a complex microbial ecosystem which helps prevent the buildup of trace gases or compounds, and thus assist with air and water purification. The atmospheric dynamics of these crops were studied in the Laboratory Biosphere adding to the database necessary for managing the mixed stands of crops essential for supplying a nutritionally

  18. Developing and implementing an integrated delirium prevention system of care: a theory driven, participatory research study

    PubMed Central

    2013-01-01

    Background Delirium is a common complication for older people in hospital. Evidence suggests that delirium incidence in hospital may be reduced by about a third through a multi-component intervention targeted at known modifiable risk factors. We describe the research design and conceptual framework underpinning it that informed the development of a novel delirium prevention system of care for acute hospital wards. Particular focus of the study was on developing an implementation process aimed at embedding practice change within routine care delivery. Methods We adopted a participatory action research approach involving staff, volunteers, and patient and carer representatives in three northern NHS Trusts in England. We employed Normalization Process Theory to explore knowledge and ward practices on delirium and delirium prevention. We established a Development Team in each Trust comprising senior and frontline staff from selected wards, and others with a potential role or interest in delirium prevention. Data collection included facilitated workshops, relevant documents/records, qualitative one-to-one interviews and focus groups with multiple stakeholders and observation of ward practices. We used grounded theory strategies in analysing and synthesising data. Results Awareness of delirium was variable among staff with no attention on delirium prevention at any level; delirium prevention was typically neither understood nor perceived as meaningful. The busy, chaotic and challenging ward life rhythm focused primarily on diagnostics, clinical observations and treatment. Ward practices pertinent to delirium prevention were undertaken inconsistently. Staff welcomed the possibility of volunteers being engaged in delirium prevention work, but existing systems for volunteer support were viewed as a barrier. Our evolving conception of an integrated model of delirium prevention presented major implementation challenges flowing from minimal understanding of delirium prevention

  19. A Symposium: Relevant Cue Research, a Program of Systematic Evaluation: Considerations for Sustaining Instructional Design Research Using an Integrated Learning System.

    ERIC Educational Resources Information Center

    Grabowski, Barbara

    An intelligent videodisc system on which comprehensive instructional development research can be conducted has been developed. This integrated learning system combines all other existing media, except objects, using a videodisc, microcomputer, printer, single monitor, hard disc storage with CPU for random access digitized audio, and headphones.…

  20. CRC Clinical Trials Management System (CTMS): An Integrated Information Management Solution for Collaborative Clinical Research

    PubMed Central

    Payne, Philip R.O.; Greaves, Andrew W.; Kipps, Thomas J.

    2003-01-01

    The Chronic Lymphocytic Leukemia (CLL) Research Consortium (CRC) consists of 9 geographically distributed sites conducting a program of research including both basic science and clinical components. To enable the CRC’s clinical research efforts, a system providing for real-time collaboration was required. CTMS provides such functionality, and demonstrates that the use of novel data modeling, web-application platforms, and management strategies provides for the deployment of an extensible, cost effective solution in such an environment. PMID:14728471

  1. The SWRL Audio Laboratory System (ALS): An Integrated Configuration for Psychomusicology Research. Technical Report 51.

    ERIC Educational Resources Information Center

    Williams, David Brian; Hoskin, Richard K.

    This report describes features of the Audio Laboratory System (ALS), a device which supports research activities of the Southwest Regional Laboratory's Music Program. The ALS is used primarily to generate recorded audio tapes for psychomusicology research related to children's perception and learning of music concepts such as pitch, loudness,…

  2. Research on the error model of airborne celestial/inertial integrated navigation system

    NASA Astrophysics Data System (ADS)

    Zheng, Xiaoqiang; Deng, Xiaoguo; Yang, Xiaoxu; Dong, Qiang

    2015-02-01

    Celestial navigation subsystem of airborne celestial/inertial integrated navigation system periodically correct the positioning error and heading drift of the inertial navigation system, by which the inertial navigation system can greatly improve the accuracy of long-endurance navigation. Thus the navigation accuracy of airborne celestial navigation subsystem directly decides the accuracy of the integrated navigation system if it works for long time. By building the mathematical model of the airborne celestial navigation system based on the inertial navigation system, using the method of linear coordinate transformation, we establish the error transfer equation for the positioning algorithm of airborne celestial system. Based on these we built the positioning error model of the celestial navigation. And then, based on the positioning error model we analyze and simulate the positioning error which are caused by the error of the star tracking platform with the MATLAB software. Finally, the positioning error model is verified by the information of the star obtained from the optical measurement device in range and the device whose location are known. The analysis and simulation results show that the level accuracy and north accuracy of tracking platform are important factors that limit airborne celestial navigation systems to improve the positioning accuracy, and the positioning error have an approximate linear relationship with the level error and north error of tracking platform. The error of the verification results are in 1000m, which shows that the model is correct.

  3. 77 FR 25488 - Cooperative Research and Development Agreement: Federally Integrated Communications System

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-30

    ...The Coast Guard is announcing its intent to enter into a Cooperative Research and Development Agreement (CRADA) with General Dynamics C4 Systems, Inc. to lab demonstrate, field test, evaluate, and document at least one technical approach to show interoperability, with end-to-end encryption, for disparate Federal communications systems at the Internet Protocol level. The Coast Guard invites......

  4. The Challenges of Developing and Integrating a Quality Management System in a Research and Development Organization

    SciTech Connect

    Ryan, E.; Werne, R.W.

    2000-08-01

    Tailoring a quality management system to the specific needs of an organization is difficult to say the least. The existence of quality system models and standards help facilitate this process immensely. However, what does an organization do when its work is so unique that quality system models and standards do not exist for it? This and other obstacles are what the Nonproliferation, Arms Control, and International Security (NAI) Directorate at Lawrence Livermore National Laboratory (LLNL) encountered during strategic initiatives to develop and integrate a new quality management system. This paper will answer this question to help similar initiatives by: Introducing NAI and its unique mission, organization, history, culture and the security environment in which it operates; Examining the obstacles to designing and integrating NAI's quality management system; Discussing the steps taken to ensure success of the strategic quality initiatives; Presenting the quality management system and plan that resulted from these efforts; Presenting the improvements in NAI and LLNL that resulted from these strategic initiatives; and Presenting lessons learned and practical recommendations.

  5. Research integrity and publication ethics.

    PubMed

    Beisiegel, Ulrike

    2010-10-01

    The basic principle for professional conduct of science in all countries and all disciplines is honesty towards oneself and towards others. Therefore it is utmost important that the scientific community prevents scientific misconduct by fostering research integrity. This commentary reports on the experience of a German 'Ombudsman' and relates it to the international concepts of good scientific practice as well as the questions of publication ethics. Biomedical research seems to be most susceptible for scientific misconduct since internationally we see many of the cases in this field. Here possible explanations for the observed misconduct are discussed as well as ways to prevent it. The intention is to both alert scientists and ultimately to adjust the scientific system in a way which allows the next generation of scientists to develop their careers in true research integrity. PMID:20692660

  6. Cooperative Research and Development for Advanced Microturbines Program on Advanced Integrated Microturbine System

    SciTech Connect

    Michael J. Bowman

    2007-05-30

    The Advanced Integrated Microturbine Systems (AIMS) project was kicked off in October of 2000 to develop the next generation microturbine system. The overall objective of the project was to develop a design for a 40% electrical efficiency microturbine system and demonstrate many of the enabling technologies. The project was initiated as a collaborative effort between several units of GE, Elliott Energy Systems, Turbo Genset, Oak Ridge National Lab and Kyocera. Since the inception of the project the partners have changed but the overall direction of the project has stayed consistent. The project began as a systems study to identify design options to achieve the ultimate goal of 40% electrical efficiency. Once the optimized analytical design was identified for the 40% system, it was determined that a 35% efficient machine would be capable of demonstrating many of the advanced technologies within the given budget and timeframe. The items that would not be experimentally demonstrated were fully produced ceramic parts. However, to understand the requirements of these ceramics, an effort was included in the project to experimentally evaluate candidate materials in representative conditions. The results from this effort would clearly identify the challenges and improvement required of these materials for the full design. Following the analytical effort, the project was dedicated to component development and testing. Each component and subsystem was designed with the overall system requirements in mind and each tested to the fullest extent possible prior to being integrated together. This method of component development and evaluation helps to minimize the technical risk of the project. Once all of the components were completed, they were assembled into the full system and experimentally evaluated.

  7. Research Integrity of Individual Scientist

    NASA Astrophysics Data System (ADS)

    Haklak, Rockbill

    We are discussing about many aspects of research integrity of individual scientist, who faces the globalization of research ethics in the traditional culture and custom of Japan. Topics are scientific misconduct (fabrication, falsification, and plagiarism) in writing paper and presenting research results. Managements of research material, research record, grant money, authorship, and conflict of interest are also analyzed and discussed. Finally, we make 5 recommendations to improve research integrity in Japan.

  8. Choosing the Right Systems Integration

    NASA Astrophysics Data System (ADS)

    Péči, Matúš; Važan, Pavel

    2014-12-01

    The paper examines systems integration and its main levels at higher levels of control. At present, the systems integration is one of the main aspects participating in the consolidation processes and financial flows of a company. Systems Integration is a complicated emotionconsuming process and it is often a problem to choose the right approach and level of integration. The research focused on four levels of integration, while each of them is characterized by specific conditions. At each level, there is a summary of recommendations and practical experience. The paper also discusses systems integration between the information and MES levels. The main part includes user-level integration where we describe an example of such integration. Finally, we list recommendations and also possible predictions of the systems integration as one of the important factors in the future.

  9. Integration of a research CBIR system with RIS and PACS for radiological routine

    NASA Astrophysics Data System (ADS)

    Fischer, Benedikt; Deserno, Thomas M.; Ott, Bastian; Günther, Rolf W.

    2008-03-01

    In this work, a concept for coupling a system for content-based image retrieval in medical applications (IRMA) with hospital information systems is presented. We aim at improving the work flow of radiologists and evaluating the recognition performance of the IRMA system in clinical routine. The integration is designed such that a failure of IRMA does not affect the routine operation of the other systems. The coupling is realized by generic communication modules with the radiology information system, and the picture archiving and communication system (PACS) over the standard protocols Digital Imaging and Communications in Medicine (DICOM) and Health Layer 7 (HL7). An optional plug-in for the radiological viewing station further enhances the usability. Based on this concept, the pre-fetching of relevant images for recurrent examinations is improved. When an examination is scheduled, all previous images of the patient are read by the IRMA system with DICOM query/retrieve. If the images were not present before in our database, features are extracted, stored, and indexed. After the acquisition of new images from the imaging modality, the new images are automatically retrieved by the IRMA system with DICOM query/retrieve and similar images are selected based on the stored global signatures. These images are then loaded into the online storage of the PACS and are available for diagnostic purposes together with those images already pre-selected by the PACS. Thus the radiologist can avoid further delays resulting from manually fetching further images from archives which have not been automatically selected by alphanumerical meta data. In addition, he is able to sort all fetched images by the computed IRMA-similarity. Furthermore, the hanging of images in the viewing software is planned to be organized by IRMA suggestions automatically, further shortening the time for the examination and reducing manual interactions. Based on the generality of our integration concept, a CBIR

  10. Optical systems integrated modeling

    NASA Technical Reports Server (NTRS)

    Shannon, Robert R.; Laskin, Robert A.; Brewer, SI; Burrows, Chris; Epps, Harlan; Illingworth, Garth; Korsch, Dietrich; Levine, B. Martin; Mahajan, Vini; Rimmer, Chuck

    1992-01-01

    An integrated modeling capability that provides the tools by which entire optical systems and instruments can be simulated and optimized is a key technology development, applicable to all mission classes, especially astrophysics. Many of the future missions require optical systems that are physically much larger than anything flown before and yet must retain the characteristic sub-micron diffraction limited wavefront accuracy of their smaller precursors. It is no longer feasible to follow the path of 'cut and test' development; the sheer scale of these systems precludes many of the older techniques that rely upon ground evaluation of full size engineering units. The ability to accurately model (by computer) and optimize the entire flight system's integrated structural, thermal, and dynamic characteristics is essential. Two distinct integrated modeling capabilities are required. These are an initial design capability and a detailed design and optimization system. The content of an initial design package is shown. It would be a modular, workstation based code which allows preliminary integrated system analysis and trade studies to be carried out quickly by a single engineer or a small design team. A simple concept for a detailed design and optimization system is shown. This is a linkage of interface architecture that allows efficient interchange of information between existing large specialized optical, control, thermal, and structural design codes. The computing environment would be a network of large mainframe machines and its users would be project level design teams. More advanced concepts for detailed design systems would support interaction between modules and automated optimization of the entire system. Technology assessment and development plans for integrated package for initial design, interface development for detailed optimization, validation, and modeling research are presented.

  11. [Research on integrated application of tumor magnetic induction hyperthermia treatment planning system and modern medical information systems].

    PubMed

    Zhuo, Zihan; Zhai, Weiming; Cai, Dongyang; Wang, Jie; Zhang, Xiaodong; Tang, Jintian

    2014-02-01

    Magnetic induction hyperthermia becomes a very important tumor treatment method at present. In order to ensure a successful operation, doctors should make hyperthermia treatment planning before surgery. Based on Integration Healthcare Enterprise (IHE) framework and Digital Imaging and Communications in Medcine (DICOM) standard, we proposed and carried out a network workflow integrated with modern medical information systems for the dissemination of information in magnetic induction hyperthermia like accurate accessing patient information and radiology image data, storing processed images, sharing and verifying hyperthermia reports. The results proved that our system could not only improve the efficiency of magnetic induction hyperthermia treatment planning, but also save medical resources and reduce labor costs. PMID:24804509

  12. Senior Research Connects Students with a Living Laboratory As Part of an Integrated Crop and Livestock System

    NASA Astrophysics Data System (ADS)

    Senturklu, Songul; Landblom, Douglas; Brevik, Eric C.

    2015-04-01

    Soil, water, soil microbes, and solar energy are the main sources that sustain life on this planet. Without them working in concert, neither plants nor animals would survive. Considering the efficiency of animal production targets, soil must be protected and improved. Therefore, through our sustainable integrated crop and livestock research, we are studying animal and soil interactions from the soil to the plate. Integrating beef cattle systems into a diverse cropping system is providing a living laboratory for education beyond the traditional classroom setting. To establish the living learning laboratory at the Dickinson Research Extension Center, a five-crop rotation was established that included adapted cool and warm season grasses and broadleaf crops. The crop rotation is: sunflower > hard red spring wheat > fall seeded winter triticale-hairy vetch (hay)/spring seeded 7-species cover crop > Corn (85-95 day varieties) > field pea-barley intercrop. Sunflower and spring wheat are harvested for cash crop income in the rotation. Livestock integration occurs when yearling steers that had previously grazed perennial pastures until mid-August graze field pea-barley and subsequently unharvested corn. Average grazing days for field pea-barley and unharvested corn is 30 and 70 days, respectively. At the end of the grazing period, the yearling steers average 499-544 kg and are moved to a feedlot and fed an additional 75 days until slaughter. Maximizing grazing days and extending the grazing season through integration with the cropping system reduces custom feeding costs and enhances animal profit. Beef cows do not require high quality feed after their calves have been weaned. Therefore, gestating beef cows are an ideal animal to graze cover crops and crop aftermath (residue) after yearling steer grazing and farming operations have been completed. Extending the grazing season for beef cows by grazing cover crops and residues reduces winter feed cost, which is one of the

  13. Senior Research Connects Students with a Living Laboratory As Part of an Integrated Crop and Livestock System

    NASA Astrophysics Data System (ADS)

    Senturklu, Songul; Landblom, Douglas; Brevik, Eric C.

    2015-04-01

    Soil, water, soil microbes, and solar energy are the main sources that sustain life on this planet. Without them working in concert, neither plants nor animals would survive. Considering the efficiency of animal production targets, soil must be protected and improved. Therefore, through our sustainable integrated crop and livestock research, we are studying animal and soil interactions from the soil to the plate. Integrating beef cattle systems into a diverse cropping system is providing a living laboratory for education beyond the traditional classroom setting. To establish the living learning laboratory at the Dickinson Research Extension Center, a five-crop rotation was established that included adapted cool and warm season grasses and broadleaf crops. The crop rotation is: sunflower > hard red spring wheat > fall seeded winter triticale-hairy vetch (hay)/spring seeded 7-species cover crop > Corn (85-95 day varieties) > field pea-barley intercrop. Sunflower and spring wheat are harvested for cash crop income in the rotation. Livestock integration occurs when yearling steers that had previously grazed perennial pastures until mid-August graze field pea-barley and subsequently unharvested corn. Average grazing days for field pea-barley and unharvested corn is 30 and 70 days, respectively. At the end of the grazing period, the yearling steers average 499-544 kg and are moved to a feedlot and fed an additional 75 days until slaughter. Maximizing grazing days and extending the grazing season through integration with the cropping system reduces custom feeding costs and enhances animal profit. Beef cows do not require high quality feed after their calves have been weaned. Therefore, gestating beef cows are an ideal animal to graze cover crops and crop aftermath (residue) after yearling steer grazing and farming operations have been completed. Extending the grazing season for beef cows by grazing cover crops and residues reduces winter feed cost, which is one of the

  14. An integrated systems biology approach to the study of preterm birth using "-omic" technology - a guideline for research

    PubMed Central

    2011-01-01

    Preterm birth is the leading cause of neonatal mortality and perinatal morbidity. The etiology of preterm is multi-factorial and still unclear. As evidence increases for a genetic contribution to PTB, so does the need to explore genomics, transcriptomics, proteomics and metabolomics in its study. This review suggests research guidelines for the conduct of high throughput systems biology investigations into preterm birth with the expectation that this will facilitate the sharing of samples and data internationally through consortia, generating the power needed to study preterm birth using integrated "-omics" technologies. The issues to be addressed include: (1) integrated "-omics" approaches, (2) phenotyping, (3) sample collection, (4) data management-integrative databases, (5) international consortia and (6) translational feasibility. This manuscript is the product of discussions initiated by the "-Omics" Working Group at the Preterm Birth International Collaborative Meeting held at the World Health Organization, Geneva, Switzerland in April 2009. PMID:21992798

  15. California Energy Commission Public Interest EnergyResearch/Energy System Integration -- Transmission-Planning Research&Development Scoping Project

    SciTech Connect

    Eto, Joseph H.; Lesieutre, Bernard; Widergren, Steven

    2004-07-01

    The objective of this Public Interest Energy Research (PIER)scoping project is to identify options for public-interest research and development (R&D) to improve transmission-planning tools, techniques, and methods. The information presented was gathered through a review of current California utility, California Independent System Operator (ISO), and related western states electricity transmission-planning activities and emerging needs. This report presents the project teams findings organized under six topic areas and identifies 17 distinct R&D activities to improve transmission-planning in California and the West. The findings in this report are intended for use, along with other materials, by PIER staff, to facilitate discussions with stakeholders that will ultimately lead to development of a portfolio of transmission-planning R&D activities for the PIER program.

  16. Integration of lessons from recent research for "Earth to Mars" life support systems

    NASA Astrophysics Data System (ADS)

    Nelson, M.; Allen, J. P.; Alling, A.; Dempster, W. F.; Silverstone, S.; van Thillo, M.

    Development of reliable and robust strategies for long-term life support for mbox planetary exploration needs to be built on real-time experimentation to verify and improve system components Also critical is the incorporation of a range of viable options to handle potential short-term life system imbalances This paper revisits some of the conceptual framework for a Mars base prototype previously advanced Mars on Earth in the light of three years of experimentation by the authors in the Laboratory Biosphere further investigation of system alternatives and the advent of other innovative engineering and agri-ecosystem approaches Several experiments with candidate space agriculture crops have demonstrated the higher productivity possible with elevated light levels and improved environmental controls For example crops of sweet potatoes exceeded original Mars base prototype projections by 83 ultradwarf Apogee wheat by 27 pinto bean by 240 and cowpeas slightly exceeded anticipated dry bean yield These production levels although they may be increased with further optimization of lighting regimes environmental parameters crop density etc offer evidence that a soil-based system can be as productive as the hydroponic systems which have dominated space life support scenarios and research Soil also offers several distinct advantages the capability to be created using in-situ space resources reducing reliance on consumables and imported resources and more easily recycling and

  17. Integrating Data from GRACE and Other Observing Systems for Hydrological Research and Applications

    NASA Technical Reports Server (NTRS)

    Rodell, M.; Famiglietti, J. S.; McWilliams, E.; Beaudoing, H. K.; Li, B.; Zaitchik, B.; Reichle, R.; Bolten, J.

    2011-01-01

    The Gravity Recovery and Climate Experiment (GRACE) mission provides a unique view of water cycle dynamics, enabling the only space based observations of water on and beneath the land surface that are not limited by depth. GRACE data are immediately useful for large scale applications such as ice sheet ablation monitoring, but they are even more valuable when combined with other types of observations, either directly or within a data assimilation system. Here we describe recent results of hydrological research and applications projects enabled by GRACE. These include the following: 1) global monitoring of interannual variability of terrestrial water storage and groundwater; 2) water balance estimates of evapotranspiration over several large river basins; 3) NASA's Energy and Water Cycle Study (NEWS) state of the global water budget project; 4) drought indicator products now being incorporated into the U.S. Drought Monitor; 5) GRACE data assimilation over several regions.

  18. Research priorities in land use and land-cover change for the Earth system and integrated assessment modelling

    SciTech Connect

    Hibbard, Kathleen A.; Janetos, Anthony C.; Van Vuuren, Detlef; Pongratz, Julia; Rose, Steven K.; Betts, Richard; Herold, Martin; Feddema, Johannes J.

    2010-11-15

    This special issue has highlighted recent and innovative methods and results that integrate observations and AQ3 modelling analyses of regional to global aspect of biophysical and biogeochemical interactions of land-cover change with the climate system. Both the Earth System and the Integrated Assessment modeling communities recognize the importance of an accurate representation of land use and land-cover change to understand and quantify the interactions and feedbacks with the climate and socio-economic systems, respectively. To date, cooperation between these communities has been limited. Based on common interests, this work discusses research priorities in representing land use and land-cover change for improved collaboration across modelling, observing and measurement communities. Major research topics in land use and land-cover change are those that help us better understand (1) the interaction of land use and land cover with the climate system (e.g. carbon cycle feedbacks), (2) the provision of goods and ecosystem services by terrestrial (natural and anthropogenic) land-cover types (e.g. food production), (3) land use and management decisions and (4) opportunities and limitations for managing climate change (for both mitigation and adaptation strategies).

  19. Intelligent test integration system

    NASA Technical Reports Server (NTRS)

    Sztipanovits, J.; Padalkar, S.; Rodriguez-Moscoso, J.; Kawamura, K.; Purves, B.; Williams, R.; Biglari, H.

    1988-01-01

    A new test technology is described which was developed for space system integration. The ultimate purpose of the system is to support the automatic generation of test systems in real time, distributed computing environments. The Intelligent Test Integration System (ITIS) is a knowledge based layer above the traditional test system components which can generate complex test configurations from the specification of test scenarios.

  20. Project Apophis for integrated research of minor body of the Solar System

    NASA Astrophysics Data System (ADS)

    Shustov, Boris M.; Martynov, Maxim; Zakharov, Alexander; Simonov, Alexander; Pol, Vadim

    The results of pre-Phase A study of the project of space mission to a minor body of the Solar System are described. For definiteness of design the famous asteroid Apophis was chosen. This hectometer size asteroid is selected as a typical potentially hazardous minor body. The study was performed in cooperation of institutes of the Russian Academy of Sciences (Space Research Institute and Institute of Astronomy) and Roscosmos (Lavochkin Association). The major goals of the mission preliminary named “Apophis” are to carry out a study of physical and chemical properties of a potentially hazardous asteroid and to put a special radio beacon into circum-asteroid orbit aimed to precise determination of the asteroid’s orbital parameters. The time schedule is connected to the upcoming close encounter of Apophis with the Earth in 2029. The period around 2020 seems to be the most reasonable window for the launch. Selection of the launch date should meet the following optimization requirements: • minimal summary velocity consumption; • maximal mass of the SC on orbit of Apophis; • favorable conditions for observation of asteroid from the Earth. General features of a mission to Apophis are described. The total mass of payload is about 800 kg. Both distant and contact (if a lander option will be included) mode of study are planned. The expected lifetime of the mission is about 5 years (10 years for the beacon). The unique science instrument for the Apophis mission is a beacon itself and system of precise registration of position and velocity of the spacecraft that uses the beacon. Besides practical things these will provide fine data for study dynamical effects of the motion of minor body in the Solar System. The science instruments designed for study of bulk characteristics of the asteroid, its internal structure, properties of regolith and exosphere are included in the payload. Most of them are analogues of the instruments included in the “Phobos-Grunt” mission

  1. Data Integration for Integrated Research and Care.

    PubMed

    Winter, Alfred; Hilgers, Ralf-Dieter; Hofestädt, Ralf; Knaup-Gregori, Petra; Ose, Claudia; Timmer, Antje

    2016-08-01

    A national German funding initiative for Medical Informatics focusing at data integration for medicine gives an opportunity to reopen a window to Germany. In the open window appears a best paper selection of the 2015 annual conference of the German Society of Medical Informatics, Biometry and Epidemiology and papers of the German journal GMS Medical Informatics, Biometry and Epidemiology (MIBE). The publications in focus deal with data integration by transferring clinical routine data into an electronic data capture (EDC) system, using natural language processing to make unstructured date processable, measuring quality of record linkage, and by using a unified metadata scheme for integrated documentation in laboratories. Two additional papers present methods for data analysis especially for change point detection in binary sequences and for analyzing categorial data. PMID:27406981

  2. Psychobiology of PTSD in the Acute Aftermath of Trauma: Integrating Research on Coping, HPA Function and Sympathetic Nervous System Activity

    PubMed Central

    Morris, Matthew C.; Rao, Uma

    2012-01-01

    Research on the psychobiological sequelae of trauma has typically focused on long-term alterations in individuals with chronic posttraumatic stress disorder (PTSD). Far less is known about the nature and course of psychobiological risk factors for PTSD during the acute aftermath of trauma. In this review, we summarize data from prospective studies focusing on the relationships among sympathetic nervous system activity, hypothalamic-pituitary-adrenal function, coping strategies and PTSD symptoms during the early recovery (or non-recovery) phase. Findings from pertinent studies are integrated to inform psychobiological profiles of PTSD-risk in children and adults in the context of existing models of PTSD-onset and maintenance. Data regarding bidirectional relations between coping strategies and stress hormones is reviewed. Limitations of existing literature and recommendations for future research are discussed. PMID:23380312

  3. Integrated cellular systems

    NASA Astrophysics Data System (ADS)

    Harper, Jason C.

    The generation of new three-dimensional (3D) matrices that enable integration of biomolecular components and whole cells into device architectures, without adversely altering their morphology or activity, continues to be an expanding and challenging field of research. This research is driven by the promise that encapsulated biomolecules and cells can significantly impact areas as diverse as biocatalysis, controlled delivery of therapeutics, environmental and industrial process monitoring, early warning of warfare agents, bioelectronics, photonics, smart prosthetics, advanced physiological sensors, portable medical diagnostic devices, and tissue/organ replacement. This work focuses on the development of a fundamental understanding of the biochemical and nanomaterial mechanisms that govern the cell directed assembly and integration process. It was shown that this integration process relies on the ability of cells to actively develop a pH gradient in response to evaporation induced osmotic stress, which catalyzes silica condensation within a thin 3D volume surrounding the cells, creating a functional bio/nano interface. The mechanism responsible for introducing functional foreign membrane-bound proteins via proteoliposome addition to the silica-lipid-cell matrix was also determined. Utilizing this new understanding, 3D cellular immobilization capabilities were extended using sol-gel matrices endowed with glycerol, trehalose, and media components. The effects of these additives, and the metabolic phase of encapsulated S. cerivisiase cells, on long-term viability and the rate of inducible gene expression was studied. This enabled the entrapment of cells within a novel microfluidic platform capable of simultaneous colorimetric, fluorescent, and electrochemical detection of a single analyte, significantly improving confidence in the biosensor output. As a complementary approach, multiphoton protein lithography was utilized to engineer 3D protein matrices in which to

  4. Integrating Single-System Design Research into the Clinical Practice Class

    ERIC Educational Resources Information Center

    Cooper, Marlene G.

    2006-01-01

    Clinical practice and research are generally taught separately in Master of Social Work programs by faculty with distinct areas of expertise. This paper discusses the teaching of single-subject design research methodology by clinical faculty, in the clinical practice class. Examples from student papers demonstrate the effectiveness of integrating…

  5. System integration report

    NASA Technical Reports Server (NTRS)

    Badler, N. I.; Korein, J. D.; Meyer, C.; Manoochehri, K.; Rovins, J.; Beale, J.; Barr, B.

    1985-01-01

    Several areas that arise from the system integration issue were examined. Intersystem analysis is discussed as it relates to software development, shared data bases and interfaces between TEMPUS and PLAID, shaded graphics rendering systems, object design (BUILD), the TEMPUS animation system, anthropometric lab integration, ongoing TEMPUS support and maintenance, and the impact of UNIX and local workstations on the OSDS environment.

  6. [Research and development of medical case database: a novel medical case information system integrating with biospecimen management].

    PubMed

    Pan, Shiyang; Mu, Yuan; Wang, Hong; Wang, Tong; Huang, Peijun; Ma, Jianfeng; Jiang, Li; Zhang, Jie; Gu, Bing; Yi, Lujiang

    2010-04-01

    To meet the needs of management of medical case information and biospecimen simultaneously, we developed a novel medical case information system integrating with biospecimen management. The database established by MS SQL Server 2000 covered, basic information, clinical diagnosis, imaging diagnosis, pathological diagnosis and clinical treatment of patient; physicochemical property, inventory management and laboratory analysis of biospecimen; users log and data maintenance. The client application developed by Visual C++ 6.0 was used to implement medical case and biospecimen management, which was based on Client/Server model. This system can perform input, browse, inquest, summary of case and related biospecimen information, and can automatically synthesize case-records based on the database. Management of not only a long-term follow-up on individual, but also of grouped cases organized according to the aim of research can be achieved by the system. This system can improve the efficiency and quality of clinical researches while biospecimens are used coordinately. It realizes synthesized and dynamic management of medical case and biospecimen, which may be considered as a new management platform. PMID:20481307

  7. The Application of System Dynamics to the Integration of National Laboratory Research and K-12 Education

    SciTech Connect

    Mills, James Ignatius; Zounar Harbour, Elda D

    2001-08-01

    The Idaho National Engineering and Environmental Laboratory (INEEL) is dedicated to finding solutions to problems related to the environment, energy, economic competitiveness, and national security. In an effort to attract and retain the expertise needed to accomplish these challenges, the INEEL is developing a program of broad educational opportunities that makes continuing education readily available to all laboratory employees, beginning in the K–12 environment and progressing through post-graduate education and beyond. One of the most innovative educational approaches being implemented at the laboratory is the application of STELLA© dynamic learning environments, which facilitate captivating K–12 introductions to the complex energy and environmental challenges faced by global societies. These simulations are integrated into lesson plans developed by teachers in collaboration with INEEL scientists and engineers. This approach results in an enjoyable and involved learning experience, and an especially positive introduction to the application of science to emerging problems of great social and environmental consequence.

  8. Systems Integration (Fact Sheet)

    SciTech Connect

    DOE Solar Energy Technologies Program

    2011-10-13

    The Systems Integration (SI) subprogram works closely with industry, universities, and the national laboratories to overcome technical barriers to the large-scale deployment of solar technologies. To support these goals, the subprogram invests primarily in four areas: grid integration, technology validation, solar resource assessment, and balance of system development.

  9. Systems Integration (Fact Sheet)

    SciTech Connect

    Not Available

    2011-10-01

    The Systems Integration (SI) subprogram works closely with industry, universities, and the national laboratories to overcome technical barriers to the large-scale deployment of solar technologies. To support these goals, the subprogram invests primarily in four areas: grid integration, technology validation, solar resource assessment, and balance of system development.

  10. Planning for an integrated research experiment

    SciTech Connect

    Barnard, J.J.; Ahle, L.E.; Bangerter, R.O.; Bieniosek, F.M.; Celata, C.M.; Faltens, A.; Friedman, A.; Grote, D.P.; Haber, I.; Henestroza, E.; Kishek, R.A.; de Hoon, M.J.L.; Karpenko, V.P.; Kirhek, R.A.; Kwan, J.W.; Lee, E.P.; Logan, B.G.; Lund, S.M.; Meier, W.R.; Molvik, A.W.; Sangster, T.C.; Seidl, P.A.; Sharp, W.M.

    2001-03-25

    We describe the goals and research program leading to the Heavy Ion Integrated Research Experiment (IRE). We review the basic constraints which lead to a design and give examples of parameters and capabilities of an IRE. We also show design tradeoffs generated by the systems code IBEAM.

  11. Integration, design, and construction of a CELSS breadboard facility for bioregenerative life support system research

    NASA Technical Reports Server (NTRS)

    Prince, R.; Knott, W.; Buchanan, Paul

    1987-01-01

    Design criteria for the Biomass Production Chamber (BPC), preliminary operating procedures, and requirements for the future development of the Controlled Ecological Life Support System (CELSS) are discussed. CELSS, which uses a bioregenerative system, includes the following three major units: (1) a biomass production component to grow plants under controlled conditions; (2) food processing components to derive maximum edible content from all plant parts; and (3) waste management components to recover and recycle all solids, liquids, and gases necessary to support life. The current status of the CELSS breadboard facility is reviewed; a block diagram of a simplified version of CELSS and schematic diagrams of the BPS are included.

  12. Integrating a framework for conducting public health systems research into statewide operations-based exercises to improve emergency preparedness

    PubMed Central

    2012-01-01

    Background Due to the uncommon nature of large-scale disasters and emergencies, public health practitioners often turn to simulated emergencies, known as “exercises”, for preparedness assessment and improvement. Under the right conditions, exercises can also be used to conduct original public health systems research. This paper describes the integration of a research framework into a statewide operations-based exercise program in California as a systems-based approach for studying public health emergency preparedness and response. Methods We developed a research framework based on the premise that operations-based exercises conducted by medical and public health agencies can be described using epidemiologic concepts. Using this framework, we conducted a survey of key local and regional medical and health agencies throughout California following the 2010 Statewide Medical and Health Exercise. The survey evaluated: (1) the emergency preparedness capabilities activated and functions performed in response to the emergency scenario, and (2) the major challenges to inter-organizational communications and information management. Results Thirty-five local health departments (LHDs), 24 local emergency medical services (EMS) agencies, 121 hospitals, and 5 Regional Disaster Medical and Health Coordinators/Specialists (RDMHC) responded to our survey, representing 57%, 77%, 26% and 83%, respectively, of target agencies in California. We found two sets of response capabilities were activated during the 2010 Statewide Exercise: a set of core capabilities that were common across all agencies, and a set of agency-specific capabilities that were more common among certain agency types. With respect to one response capability in particular, inter-organizational information sharing, we found that the majority of respondents’ comments were related to the complete or partial failure of communications equipment or systems. Conclusions Using the 2010 Statewide Exercise in California

  13. How to integrate biological research into society and exclude errors in biomedical publications? Progress in theoretical and systems biology releases pressure on experimental research

    PubMed Central

    Volkov, Vadim

    2014-01-01

    This brief opinion proposes measures to increase efficiency and exclude errors in biomedical research under the existing dynamic situation. Rapid changes in biology began with the description of the three dimensional structure of DNA 60 years ago; today biology has progressed by interacting with computer science and nanoscience together with the introduction of robotic stations for the acquisition of large-scale arrays of data. These changes have had an increasing influence on the entire research and scientific community. Future advance demands short-term measures to ensure error-proof and efficient development. They can include the fast publishing of negative results, publishing detailed methodical papers and excluding a strict connection between career progression and publication activity, especially for younger researchers. Further development of theoretical and systems biology together with the use of multiple experimental methods for biological experiments could also be helpful in the context of years and decades. With regards to the links between science and society, it is reasonable to compare both these systems, to find and describe specific features for biology and to integrate it into the existing stream of social life and financial fluxes. It will increase the level of scientific research and have mutual positive effects for both biology and society. Several examples are given for further discussion. PMID:24748913

  14. Integrating research into operational practice.

    PubMed

    Ross, Alastair

    2015-08-01

    Research and development can be classified into three categories: technology adoption, technology extension, and knowledge and technology creation. In general, technology adoption is embedded in operational forensic science laboratory practice but the latter two categories require partnerships with industry and/or academia both to conduct the research and implement the outcomes. In a 2012 survey, Australian and New Zealand forensic science laboratories identified a number of 'roadblocks' to undertaking research and operationalizing research outcomes. These included insufficient time and funding, a lack of in-house research experience and the absence of a tangible research culture. Allied to this is that, increasingly, forensic science research is conducted in a 'commercial in confidence' environment and the outcomes are not readily or cost-effectively available to be integrated into operational forensic science laboratories. The paper is predominantly reflective of the current situation in Australia and New Zealand. PMID:26101286

  15. Integrating research into operational practice

    PubMed Central

    Ross, Alastair

    2015-01-01

    Research and development can be classified into three categories: technology adoption, technology extension, and knowledge and technology creation. In general, technology adoption is embedded in operational forensic science laboratory practice but the latter two categories require partnerships with industry and/or academia both to conduct the research and implement the outcomes. In a 2012 survey, Australian and New Zealand forensic science laboratories identified a number of ‘roadblocks’ to undertaking research and operationalizing research outcomes. These included insufficient time and funding, a lack of in-house research experience and the absence of a tangible research culture. Allied to this is that, increasingly, forensic science research is conducted in a ‘commercial in confidence’ environment and the outcomes are not readily or cost-effectively available to be integrated into operational forensic science laboratories. The paper is predominantly reflective of the current situation in Australia and New Zealand PMID:26101286

  16. Promoting research integrity in the geosciences

    NASA Astrophysics Data System (ADS)

    Mayer, Tony

    2015-04-01

    Conducting research in a responsible manner in compliance with codes of research integrity is essential. The geosciences, as with all other areas of research endeavour, has its fair share of misconduct cases and causes celebres. As research becomes more global, more collaborative and more cross-disciplinary, the need for all concerned to work to the same high standards becomes imperative. Modern technology makes it far easier to 'cut and paste', to use Photoshop to manipulate imagery to falsify results at the same time as making research easier and more meaningful. So we need to promote the highest standards of research integrity and the responsible conduct of research. While ultimately, responsibility for misconduct rests with the individual, institutions and the academic research system have to take steps to alleviate the pressure on researchers and promote good practice through training programmes and mentoring. The role of the World Conferences on Research Integrity in promoting the importance of research integrity and statements about good practice will be presented and the need for training and mentoring programmes will be discussed

  17. A field evaluation of remote sensor measurements of wind, temperature, and moisture for ARM integrated sounding system research

    SciTech Connect

    Martner, B.E.; Westwater, E.R.; Strauch, R.G.

    1993-10-01

    Remote sensing systems were operated in Colorado in February and March 1991 to obtain detailed profiles of the kinematic and thermodynamic structure of the atmosphere for the US Department of Energy`s Atmospheric Radiation Measurement (ARM) research program. The instruments included wind profilers, Radio Acoustic Sounding Systems (PASS), microwave and infrared radiometers, an infrared spectrometer, ceilometers, radiosondes, surface meteorological stations, and other equipment. A mesoscale data assimilation model will be used to combine the data into dynamically consistent four-dimensional fields as part of an integrated data assimilation sounding system. This report evaluates the performance of the NOAA remote sensors used in the 1991 field data collection. These included five different wind profilers, each equipped with RASS capability for temperature profiling, and microwave radiometers for measurements of pathintegrated water vapor and liquid water content. The design and initial testing of a Fourier-transform InfraRed Sounder (FIRS) for humidity profiling is also described. The ranges of height coverage and measurement accuracies for each wind profiler/RASS are examined. Specific recommendations for optimizing the design and configuration of similar instruments are made for the ARM cloud and Radiation Testbed (CART) sites, based on results of the 1991 field work and earlier tests. Examples of routine processed data products are presented for three intensive operating period studies to further illustrate the remote sensors` capabilities.

  18. Human Systems Integration Introduction

    NASA Video Gallery

    This lecture provides an overview of Human Systems Integration (HSI), its implementation cost and return on investment, HSI domains, how HSI fits into the NASA organization structure, HSI roles and...

  19. The Benefits of a Comprehensive, Integrated, and Granular Data System for Community and Technical College Institutional Research

    ERIC Educational Resources Information Center

    Schoenecker, Craig

    2010-01-01

    This chapter describes the system office for community college institutional research for the Minnesota State Colleges and Universities. What makes this System Offices for Community College Institutional Research (SOCCIR) somewhat different from the others reviewed in this volume is that the Minnesota system IR office has responsibilities for both…

  20. Prototype of an Integrated Hurricane Information System for Research: Design and Implementation of the Database and Web Portal

    NASA Astrophysics Data System (ADS)

    Li, P. P.; Knosp, B.; Vu, Q. A.; Hristova-Veleva, S.; Chao, Y.; Vane, D.; Lambrigtsen, B.; Su, H.; Dang, V.; Fovell, R.; Willis, J.; Tanelli, S.; Fishbein, E.; Ao, C. O.; Poulsen, W. L.; Park, K. J.; Fetzer, E.; Vazquez, J.; Callahan, P. S.; Marcus, S.; Garay, M.; Kahn, R.; Haddad, Z.

    2007-12-01

    Many hurricane websites provide historical hurricane information and real-time storm tracking. These sites often include images from various remote-sensing satellite sensors with such atmospheric and oceanic quantities as wind, temperature, rain, and water vapor. However, it has been determined that the hurricane analysis community is lacking a web portal that provides researchers a comprehensive set of observed hurricane parameters (both graphics and data) together with large-scale and convection-resolving model output. We have developed a prototype of an integrated hurricane information system of high-resolution satellite and in- situ observations along with model outputs pertaining to: i) the thermodynamic and microphysical structure of storms; ii) the air-sea interaction processes; iii) the larger-scale environment as depicted by quantities such as SST, ocean heat content and the aerosol loading of the environment. Our goal is to provide a one-stop place to access all the available information of a specific hurricane for researchers to advance the understanding, modeling and predication of hurricane genesis and intensity changes. Our hurricane information system prototype consists of high-resolution satellite data measuring three- dimensional atmospheric and oceanic parameters that includes observations from AIRS, MISR, MODIS, CloudSAT, AMSR-E, TRMM, GOES, MLS, QuikSCAT, SeaWiFS, and COSMIC GPS, in-situ observations such as ARGO floats, large scale data assimilation products from NCEP, and high resolution hurricane model output from WRF. High-resolution satellite data are sub-setted within 2000-kilometer-square area centered at the closest storm location and large-scale environmental datasets are divided into 6 predefined geographical regions. When accessing this hurricane portal, users may browse through data by year, region, category, and hurricane. At the front page, we show the hurricane track using Google Map. Users may pan and zoom, or click on the track

  1. Integrated Avionics System (IAS)

    NASA Technical Reports Server (NTRS)

    Hunter, D. J.

    2001-01-01

    As spacecraft designs converge toward miniaturization and with the volumetric and mass constraints placed on avionics, programs will continue to advance the 'state of the art' in spacecraft systems development with new challenges to reduce power, mass, and volume. Although new technologies have improved packaging densities, a total system packaging architecture is required that not only reduces spacecraft volume and mass budgets, but increase integration efficiencies, provide modularity and scalability to accommodate multiple missions. With these challenges in mind, a novel packaging approach incorporates solutions that provide broader environmental applications, more flexible system interconnectivity, scalability, and simplified assembly test and integration schemes. This paper will describe the fundamental elements of the Integrated Avionics System (IAS), Horizontally Mounted Cube (HMC) hardware design, system and environmental test results. Additional information is contained in the original extended abstract.

  2. Integrated clinical information system.

    PubMed

    Brousseau, G

    1995-01-01

    SIDOCI (Système Informatisé de DOnnées Cliniques Intégrées) is a Canadian joint venture introducing newly-operating paradigms into hospitals. The main goal of SIDOCI is to maintain the quality of care in todayUs tightening economy. SIDOCI is a fully integrated paperless patient-care system which automates and links all information about a patient. Data is available on-line and instantaneously to doctors, nurses, and support staff in the format that best suits their specific requirements. SIDOCI provides a factual and chronological summary of the patient's progress by drawing together clinical information provided by all professionals working with the patient, regardless of their discipline, level of experience, or physical location. It also allows for direct entry of the patient's information at the bedside. Laboratory results, progress notes, patient history and graphs are available instantaneously on screen, eliminating the need for physical file transfers. The system, incorporating a sophisticated clinical information database, an intuitive graphical user interface, and customized screens for each medical discipline, guides the user through standard procedures. Unlike most information systems created for the health care industry, SIDOCI is longitudinal, covering all aspects of the health care process through its link to various vertical systems already in place. A multidisciplinary team has created a clinical dictionary that provides the user with most of the information she would normally use: symptoms, signs, diagnoses, allergies, medications, interventions, etc. This information is structured and displayed in such a manner that health care professionals can document the clinical situation at the touch of a finger. The data is then encoded into the patient's file. Once encoded, the structured data is accessible for research, statistics, education, and quality assurance. This dictionary complies with national and international nomenclatures. It also

  3. Integrative radiation systems biology.

    PubMed

    Unger, Kristian

    2014-01-01

    Maximisation of the ratio of normal tissue preservation and tumour cell reduction is the main concept of radiotherapy alone or combined with chemo-, immuno- or biologically targeted therapy. The foremost parameter influencing this ratio is radiation sensitivity and its modulation towards a more efficient killing of tumour cells and a better preservation of normal tissue at the same time is the overall aim of modern therapy schemas. Nevertheless, this requires a deep understanding of the molecular mechanisms of radiation sensitivity in order to identify its key players as potential therapeutic targets. Moreover, the success of conventional approaches that tried to statistically associate altered radiation sensitivity with any molecular phenotype such as gene expression proofed to be somewhat limited since the number of clinically used targets is rather sparse. However, currently a paradigm shift is taking place from pure frequentistic association analysis to the rather holistic systems biology approach that seeks to mathematically model the system to be investigated and to allow the prediction of an altered phenotype as the function of one single or a signature of biomarkers. Integrative systems biology also considers the data from different molecular levels such as the genome, transcriptome or proteome in order to partially or fully comprehend the causal chain of molecular mechanisms. An example for the application of this concept currently carried out at the Clinical Cooperation Group "Personalized Radiotherapy in Head and Neck Cancer" of the Helmholtz-Zentrum München and the LMU Munich is described. This review article strives for providing a compact overview on the state of the art of systems biology, its actual challenges, potential applications, chances and limitations in radiation oncology research working towards improved personalised therapy concepts using this relatively new methodology. PMID:24411063

  4. Modular integrated video system

    SciTech Connect

    Gaertner, K.J.; Heaysman, B.; Holt, R.; Sonnier, C.

    1986-01-01

    The Modular Integrated Video System (MIVS) is intended to provide a simple, highly reliable closed circuit television (CCTV) system capable of replacing the IAEA Twin Minolta Film Camera Systems in those safeguards facilities where mains power is readily available, and situations where it is desired to have the CCTV camera separated from the CCTV recording console. This paper describes the MIVS and the Program Plan which is presently being followed for the development, testing, and implementation of the system.

  5. Aviation Data Integration System

    NASA Technical Reports Server (NTRS)

    Kulkarni, Deepak; Wang, Yao; Windrem, May; Patel, Hemil; Keller, Richard

    2003-01-01

    During the analysis of flight data and safety reports done in ASAP and FOQA programs, airline personnel are not able to access relevant aviation data for a variety of reasons. We have developed the Aviation Data Integration System (ADIS), a software system that provides integrated heterogeneous data to support safety analysis. Types of data available in ADIS include weather, D-ATIS, RVR, radar data, and Jeppesen charts, and flight data. We developed three versions of ADIS to support airlines. The first version has been developed to support ASAP teams. A second version supports FOQA teams, and it integrates aviation data with flight data while keeping identification information inaccessible. Finally, we developed a prototype that demonstrates the integration of aviation data into flight data analysis programs. The initial feedback from airlines is that ADIS is very useful in FOQA and ASAP analysis.

  6. On Quantum Integrable Systems

    SciTech Connect

    Danilov, Viatcheslav; Nagaitsev, Sergei; /Fermilab

    2011-11-01

    Many quantum integrable systems are obtained using an accelerator physics technique known as Ermakov (or normalized variables) transformation. This technique was used to create classical nonlinear integrable lattices for accelerators and nonlinear integrable plasma traps. Now, all classical results are carried over to a nonrelativistic quantum case. In this paper we have described an extension of the Ermakov-like transformation to the Schroedinger and Pauli equations. It is shown that these newly found transformations create a vast variety of time dependent quantum equations that can be solved in analytic functions, or, at least, can be reduced to time-independent ones.

  7. Integrated work management system.

    SciTech Connect

    Williams, Edward J., Jr.; Henry, Karen Lynne

    2010-06-01

    Sandia National Laboratories develops technologies to: (1) sustain, modernize, and protect our nuclear arsenal (2) Prevent the spread of weapons of mass destruction; (3) Provide new capabilities to our armed forces; (4) Protect our national infrastructure; (5) Ensure the stability of our nation's energy and water supplies; and (6) Defend our nation against terrorist threats. We identified the need for a single overarching Integrated Workplace Management System (IWMS) that would enable us to focus on customer missions and improve FMOC processes. Our team selected highly configurable commercial-off-the-shelf (COTS) software with out-of-the-box workflow processes that integrate strategic planning, project management, facility assessments, and space management, and can interface with existing systems, such as Oracle, PeopleSoft, Maximo, Bentley, and FileNet. We selected the Integrated Workplace Management System (IWMS) from Tririga, Inc. Facility Management System (FMS) Benefits are: (1) Create a single reliable source for facility data; (2) Improve transparency with oversight organizations; (3) Streamline FMOC business processes with a single, integrated facility-management tool; (4) Give customers simple tools and real-time information; (5) Reduce indirect costs; (6) Replace approximately 30 FMOC systems and 60 homegrown tools (such as Microsoft Access databases); and (7) Integrate with FIMS.

  8. Integrating Research Competencies in Massage Therapy Education.

    ERIC Educational Resources Information Center

    Hymel, Glenn M.

    The massage therapy profession is currently engaged in a competency-based education movement that includes an emphasis on promoting massage therapy research competencies (MTRCs). A systems-based model for integrating MTRCs into massage therapy education was therefore proposed. The model and an accompanying checklist describe an approach to…

  9. Toward Systems Understanding of Leaf Senescence: An Integrated Multi-Omics Perspective on Leaf Senescence Research.

    PubMed

    Kim, Jeongsik; Woo, Hye Ryun; Nam, Hong Gil

    2016-06-01

    Leaf senescence is a complex but tightly regulated developmental process involving a coordinated sequence of multiple molecular events, which ultimately leads to death of the leaf. Efforts to understand the mechanistic principles underlying leaf senescence have been largely made by transcriptomic, proteomic, and metabolomic studies over the past decade. This review focuses on recent milestones in leaf senescence research obtained using multi-omics technologies, as well as future endeavors toward systems understanding of leaf senescence processes. In particular, we discuss recent advances in understanding molecular events during leaf senescence through genome-wide transcriptome analyses in Arabidopsis. We also describe comparative transcriptome analyses used to unveil the commonality and diversity of regulatory mechanisms governing leaf senescence in the plant kingdom. Finally, we provide current illustrations of epigenomic, proteomic, and metabolomic landscapes of leaf senescence. We envisage that integration of multi-omics leaf senescence data will enable us to address unresolved questions regarding leaf senescence, including determining the molecular principles that coordinate concurrent and ordered changes in biological events during leaf senescence. PMID:27174403

  10. Integrated system design report

    SciTech Connect

    Not Available

    1989-07-01

    The primary objective of the integrated system test phase is to demonstrate the commercial potential of a coal fueled diesel engine in its actual operating environment. The integrated system in this project is defined as a coal fueled diesel locomotive. This locomotive, shown on drawing 41D715542, is described in the separate Concept Design Report. The test locomotive will be converted from an existing oil fueled diesel locomotive in three stages, until it nearly emulates the concept locomotive. Design drawings of locomotive components (diesel engine, locomotive, flatcar, etc.) are included.

  11. Integrated data acquisition system for medical device testing and physiology research in compliance with good laboratory practices.

    PubMed

    Koenig, Steven C; Woolard, Cary; Drew, Guy; Unger, Lauren; Gillars, Kevin; Ewert, Dan; Gray, Laman; Pantalos, George

    2004-01-01

    In seeking approval from the US Food and Drug Administration (FDA) for clinical trial evaluation of an experimental medical device, a sponsor is required to submit experimental findings and support documentation to demonstrate device safety and efficacy that are in compliance with Good Laboratory Practices (GLP). The objective of this project was to develop an integrated data acquisition (DAQ) system and documentation strategy for monitoring and recording physiological data when testing medical devices in accordance with GLP guidelines mandated by the FDA. Data aquisition systems were developed as stand-alone instrumentation racks containing transducer amplifiers and signal processors, analog-to-digital converters for data storage, visual display and graphical user-interfaces, power conditioners, and test measurement devices. Engineering standard operating procedures (SOP) were developed to provide a written step-by-step process for calibrating, validating, and certifying each individual instrumentation unit and the integrated DAQ system. Engineering staff received GLP and SOP training and then completed the calibration, validation, and certification process for the individual instrumentation components and integrated DAQ system. Eight integrated DAQ systems have been successfully developed that were inspected by regulatory affairs consultants and determined to meet GLP guidelines. Two of these DAQ systems were used to support 40 of the pre-clinical animal studies evaluating the AbiCor artificial heart (ABIOMED, Danvers, MA). Based in part on these pre-clinical animal data, the AbioCor clinical trials began in July 2001. The process of developing integrated DAQ systems, SOP, and the validation and certification methods used to ensure GLP compliance are presented in this article. PMID:15174367

  12. Power systems integration

    SciTech Connect

    Brantley, L.W.

    1982-06-01

    Power systems integration in large flexible space structures is discussed with emphasis upon body control. A solar array is discussed as a typical example of spacecraft configuration problems. Information on how electric batteries dominate life-cycle costs is presented in chart form. Information is given on liquid metal droplet generators and collectors, hot spot analysis, power dissipation in solar arrays, solar array protection optimization, and electromagnetic compatibility for a power system platform.

  13. Making research integral to home care services.

    PubMed

    Lang, Ariella; Shamian, Judith; Goodwin, Sharon

    2015-09-01

    Home care is the fastest growing segment of the Canadian healthcare system, yet research on patient safety has been conducted predominantly in institutional settings. This is a case example of how Victorian Order of Nurses Canada, a national not-for-profit home and community care provider, embedded a nurse researcher to create an environment in which health services research flourished. This model strategically propelled important issues such as home care safety on to the national research and policy agendas and helped leverage change in multiple levels of the healthcare system. This is a call to action for building partnerships to have a researcher as an integral team member in organizations providing home care services. PMID:26135296

  14. An Integrated Extravehicular Activity Research Plan

    NASA Technical Reports Server (NTRS)

    Abercromby, Andrew F. J.; Ross, Amy J.; Cupples, J. Scott

    2016-01-01

    Multiple organizations within NASA and outside of NASA fund and participate in research related to extravehicular activity (EVA). In October 2015, representatives of the EVA Office, the Crew and Thermal Systems Division (CTSD), and the Human Research Program (HRP) at NASA Johnson Space Center agreed on a formal framework to improve multi-year coordination and collaboration in EVA research. At the core of the framework is an Integrated EVA Research Plan and a process by which it will be annually reviewed and updated. The over-arching objective of the collaborative framework is to conduct multi-disciplinary cost-effective research that will enable humans to perform EVAs safely, effectively, comfortably, and efficiently, as needed to enable and enhance human space exploration missions. Research activities must be defined, prioritized, planned and executed to comprehensively address the right questions, avoid duplication, leverage other complementary activities where possible, and ultimately provide actionable evidence-based results in time to inform subsequent tests, developments and/or research activities. Representation of all appropriate stakeholders in the definition, prioritization, planning and execution of research activities is essential to accomplishing the over-arching objective. A formal review of the Integrated EVA Research Plan will be conducted annually. External peer review of all HRP EVA research activities including compilation and review of published literature in the EVA Evidence Book is already performed annually. Coordination with stakeholders outside of the EVA Office, CTSD, and HRP is already in effect on a study-by-study basis; closer coordination on multi-year planning with other EVA stakeholders including academia is being actively pursued. Details of the current Integrated EVA Research Plan are presented including description of ongoing and planned research activities in the areas of: Benchmarking; Anthropometry and Suit Fit; Sensors; Human

  15. Intelligent systems technology infrastructure for integrated systems

    NASA Technical Reports Server (NTRS)

    Lum, Henry, Jr.

    1991-01-01

    Significant advances have occurred during the last decade in intelligent systems technologies (a.k.a. knowledge-based systems, KBS) including research, feasibility demonstrations, and technology implementations in operational environments. Evaluation and simulation data obtained to date in real-time operational environments suggest that cost-effective utilization of intelligent systems technologies can be realized for Automated Rendezvous and Capture applications. The successful implementation of these technologies involve a complex system infrastructure integrating the requirements of transportation, vehicle checkout and health management, and communication systems without compromise to systems reliability and performance. The resources that must be invoked to accomplish these tasks include remote ground operations and control, built-in system fault management and control, and intelligent robotics. To ensure long-term evolution and integration of new validated technologies over the lifetime of the vehicle, system interfaces must also be addressed and integrated into the overall system interface requirements. An approach for defining and evaluating the system infrastructures including the testbed currently being used to support the on-going evaluations for the evolutionary Space Station Freedom Data Management System is presented and discussed. Intelligent system technologies discussed include artificial intelligence (real-time replanning and scheduling), high performance computational elements (parallel processors, photonic processors, and neural networks), real-time fault management and control, and system software development tools for rapid prototyping capabilities.

  16. Integrated oxygen recovery system

    NASA Technical Reports Server (NTRS)

    Lee, M. Gene; Davenport, Ronald J.

    1993-01-01

    Life Systems has conceptualized an innovative Integrated Oxygen Recovery System (IORS) applicable to advanced mission air revitalization. The IORS provides the capability to electrochemically generate metabolic oxygen (O2) and recover O2 from the space habitat atmosphere via a carbon dioxide (CO2) reduction process within a single assembly. To achieve this capability, the IORS utilizes a Solid Metal Cathode (SMC) water electrolysis unit that simultaneously serves as the Sabatier CO2 reduction reactor. The IORS enables two major life support systems currently baselined in closed loop air revitalization systems to be combined into one smaller, less complex system. This concept reduces fluidic and electrical interface requirements and eliminates a hydrogen (H2) interface. Life Systems is performing an evaluation of the IORS process directed at demonstrating performance and quantifying key physical characteristics including power, weight, and volume. The results of the checkout, shakedown, and initial parametric tests are summarized.

  17. Integrated oxygen recovery system

    NASA Technical Reports Server (NTRS)

    Lee, M. Gene; Davenport, Ronald J.

    1993-01-01

    Life Systems has conceptualized an innovative Integrated Oxygen Recovery System (IORS) applicable to advanced mission air revitalization. The IORS provides the capability to electrochemically generate metabolic oxygen (O2) and recover O2 from the space habitat atmosphere via a carbon dioxide (CO2) reduction process within a single assembly. To achieve this capability, the IORS utilizes a Solid Metal Cathode (SMC) water electrolysis unit that simultaneously serves as the Sabatier CO2 reduction reactor. The IORS enables two major life support systems currently baselined in closed loop air revitalization systems to be combined into one smaller, less complex system. This concept reduces fluidic and electrical interface requirements and eliminates a hydrogen (H2) interface. Life Systems is performing an evaluation of the IORS process directed at demonstrating performance and quantifying key physical characteristics including power, weight, and volume. Technical progress achieved during the first two months of the program is summarized.

  18. Integrating and Interfacing Library Systems.

    ERIC Educational Resources Information Center

    Boss, Richard W.

    1985-01-01

    This overview of local library online systems that integrate several functions covers functional integration, benefits of integrated systems, turnkey systems, minicomputer and microcomputer-based systems, interfacing automated systems, types of interfaces, linking homogenous and heterogeneous systems, role of vendors, library applications, linking…

  19. The Undiagnosed Diseases Program Integrated Collaboration System (UDPICS): One Program's Experience Developing Custom Software to Support Research for Complex-Disease Families.

    PubMed

    Guzman, Jessica; Lee, Elizabeth; Draper, David; Valivullah, Zaheer; Yu, Guoyun; Sincan, Murat; Gahl, William A; Adams, David R

    2015-01-01

    The Undiagnosed Diseases Program (UDP) was started in 2008 with the goals of making diagnoses and facilitating related translational research. The individuals and families seen by the UDP are often unique and medically complex. Approximately 40% of UDP cases are pediatric. The Undiagnosed Diseases Program Integrated Collaboration System (UDPICS) was designed to create a collaborative workspace for researchers, clinicians and families. We describe our progress in developing the system to date, focusing on design rationale, challenges and issues that are likely to be common in the development of similar systems in the future. PMID:27417368

  20. The Undiagnosed Diseases Program Integrated Collaboration System (UDPICS): One Program’s Experience Developing Custom Software to Support Research for Complex-Disease Families

    PubMed Central

    Guzman, Jessica; Lee, Elizabeth; Draper, David; Valivullah, Zaheer; Yu, Guoyun; Sincan, Murat; Gahl, William A.; Adams, David R.

    2015-01-01

    The Undiagnosed Diseases Program (UDP) was started in 2008 with the goals of making diagnoses and facilitating related translational research. The individuals and families seen by the UDP are often unique and medically complex. Approximately 40% of UDP cases are pediatric. The Undiagnosed Diseases Program Integrated Collaboration System (UDPICS) was designed to create a collaborative workspace for researchers, clinicians and families. We describe our progress in developing the system to date, focusing on design rationale, challenges and issues that are likely to be common in the development of similar systems in the future. PMID:27417368

  1. Integrated Systems Health Management for Intelligent Systems

    NASA Technical Reports Server (NTRS)

    Figueroa, Fernando; Melcher, Kevin

    2011-01-01

    The implementation of an integrated system health management (ISHM) capability is fundamentally linked to the management of data, information, and knowledge (DIaK) with the purposeful objective of determining the health of a system. It is akin to having a team of experts who are all individually and collectively observing and analyzing a complex system, and communicating effectively with each other in order to arrive at an accurate and reliable assessment of its health. In this paper, concepts, procedures, and approaches are presented as a foundation for implementing an intelligent systems ]relevant ISHM capability. The capability stresses integration of DIaK from all elements of a system. Both ground-based (remote) and on-board ISHM capabilities are compared and contrasted. The information presented is the result of many years of research, development, and maturation of technologies, and of prototype implementations in operational systems.

  2. Power Systems Integration Laboratory (Fact Sheet)

    SciTech Connect

    Not Available

    2011-10-01

    This fact sheet describes the purpose, lab specifications, applications scenarios, and information on how to partner with NREL's Power Systems Integration Laboratory at the Energy Systems Integration Facility. At NREL's Power Systems Integration Laboratory in the Energy Systems Integration Facility (ESIF), research focuses on developing and testing large-scale distributed energy systems for grid-connected, stand-alone, and microgrid applications. The laboratory can accommodate large power system components such as inverters for photovoltaic (PV) and wind systems, diesel and natural gas generators, battery packs, microgrid interconnection switchgear, and vehicles. Closely coupled with the research electrical distribution bus at the ESIF, the Power Systems Integration Laboratory will offer power testing capability of megawatt-scale DC and AC power systems, as well as advanced hardware-in-the-loop and model-in-the-loop simulation capabilities. Thermal heating and cooling loops and fuel also allow testing of combined heating/cooling and power systems (CHP).

  3. Slimplectic Integrators: Variational Integrators for Nonconservative systems

    NASA Astrophysics Data System (ADS)

    Tsang, David

    2016-05-01

    Symplectic integrators are widely used for long-term integration of conservative astrophysical problems due to their ability to preserve the constants of motion; however, they cannot in general be applied in the presence of nonconservative interactions. Here we present the “slimplectic” integrator, a new type of numerical integrator that shares many of the benefits of traditional symplectic integrators yet is applicable to general nonconservative systems. We utilize a fixed-time-step variational integrator formalism applied to a newly developed principle of stationary nonconservative action (Galley, 2013, Galley et al 2014). As a result, the generalized momenta and energy (Noether current) evolutions are well-tracked. We discuss several example systems, including damped harmonic oscillators, Poynting–Robertson drag, and gravitational radiation reaction, by utilizing our new publicly available code to demonstrate the slimplectic integrator algorithm. Slimplectic integrators are well-suited for integrations of systems where nonconservative effects play an important role in the long-term dynamical evolution. As such they are particularly appropriate for cosmological or celestial N-body dynamics problems where nonconservative interactions, e.g., gas interactions or dissipative tides, can play an important role.

  4. Slimplectic Integrators: Variational Integrators for Nonconservative systems

    NASA Astrophysics Data System (ADS)

    Tsang, David

    2016-01-01

    Symplectic integrators are widely used for long-term integration of conservative astrophysical problems due to their ability to preserve the constants of motion; however, they cannot in general be applied in the presence of nonconservative interactions. In this Letter, we develop the "slimplectic" integrator, a new type of numerical integrator that shares many of the benefits of traditional symplectic integrators yet is applicable to general nonconservative systems. We utilize a fixed-time-step variational integrator formalism applied to the principle of stationary nonconservative action developed in Galley et al. As a result, the generalized momenta and energy (Noether current) evolutions are well-tracked. We discuss several example systems, including damped harmonic oscillators, Poynting-Robertson drag, and gravitational radiation reaction, by utilizing our new publicly available code to demonstrate the slimplectic integrator algorithm. Slimplectic integrators are well-suited for integrations of systems where nonconservative effects play an important role in the long-term dynamical evolution. As such they are particularly appropriate for cosmological or celestial N-body dynamics problems where nonconservative interactions, e.g., gas interactions or dissipative tides, can play an important role.

  5. Integrated traffic system

    SciTech Connect

    Creighton, H. ); Allen, R.; Stewart, S.; Hayto, S. )

    1990-11-01

    The traffic congestion on our roads today is becoming a critical problem. There is increased fuel consumption as cars wait along poorly timed arterials. Safety is threatened as poor traffic flow leads to collisions. This paper reports that Transport Canada and the Ministry of Transportation Ontario has developed an integrated traffic system (ITS). The system is designed to enable the optimization of traffic flow on existing roadways. The ITS system contains a data-base management system for traffic data (including accidents, roadway volumes, and signal timing details) and links this data base to the traffic analysis programs. This will ease the data management situation within the municipalities and standardize the traffic operations and reduce duplication of computerization development efforts.

  6. Lunar materials processing system integration

    NASA Astrophysics Data System (ADS)

    Sherwood, Brent

    1992-02-01

    The theme of this paper is that governmental resources will not permit the simultaneous development of all viable lunar materials processing (LMP) candidates. Choices will inevitably be made, based on the results of system integration trade studies comparing candidates to each other for high-leverage applications. It is in the best long-term interest of the LMP community to lead the selection process itself, quickly and practically. The paper is in five parts. The first part explains what systems integration means and why the specialized field of LMP needs this activity now. The second part defines the integration context for LMP -- by outlining potential lunar base functions, their interrelationships and constraints. The third part establishes perspective for prioritizing the development of LMP methods, by estimating realistic scope, scale, and timing of lunar operations. The fourth part describes the use of one type of analytical tool for gaining understanding of system interactions: the input/output model. A simple example solved with linear algebra is used to illustrate. The fifth and closing part identifies specific steps needed to refine the current ability to study lunar base system integration. Research specialists have a crucial role to play now in providing the data upon which this refinement process must be based.

  7. Lunar materials processing system integration

    NASA Technical Reports Server (NTRS)

    Sherwood, Brent

    1992-01-01

    The theme of this paper is that governmental resources will not permit the simultaneous development of all viable lunar materials processing (LMP) candidates. Choices will inevitably be made, based on the results of system integration trade studies comparing candidates to each other for high-leverage applications. It is in the best long-term interest of the LMP community to lead the selection process itself, quickly and practically. The paper is in five parts. The first part explains what systems integration means and why the specialized field of LMP needs this activity now. The second part defines the integration context for LMP -- by outlining potential lunar base functions, their interrelationships and constraints. The third part establishes perspective for prioritizing the development of LMP methods, by estimating realistic scope, scale, and timing of lunar operations. The fourth part describes the use of one type of analytical tool for gaining understanding of system interactions: the input/output model. A simple example solved with linear algebra is used to illustrate. The fifth and closing part identifies specific steps needed to refine the current ability to study lunar base system integration. Research specialists have a crucial role to play now in providing the data upon which this refinement process must be based.

  8. The Integral System

    PubMed Central

    2011-01-01

    The Integral System is a total care management system based on the Integral Theory which states ‘prolapse and symptoms of urinary stress, urge, abnormal bowel & bladder emptying, and some forms of pelvic pain, mainly arise, for different reasons, from laxity in the vagina or its supporting ligaments, a result of altered connective tissue’. Normal function The organs are suspended by ligaments against which muscles contract to open or close the their outlet tubes, urethra and anus. These ligaments fall naturally into a three-zone zone classification, anterior, middle, and posterior. Dysfunction Damaged ligaments weaken the force of muscle contraction, causing prolapse and abnormal bladder and bowel symptoms Diagnosis A pictorial diagnostic algorithm relates specific symptoms to damaged ligaments in each zone. Treatment In mild cases, new pelvic floor muscle exercises based on a squatting principle strengthen the natural closure muscles and their ligamentous insertions, thereby improving the symptoms predicted by the Theory. With more severe cases, polypropylene tapes applied through “keyhole” incision using special instruments reinforce the damaged ligaments, restoring structure and function. Problems that can be potentially addressed by application of the Integral System Urinary stress incontinenceUrinary urge incontinenceAbnormal bladder emptyingFacal incontinence and “obstructed evacuation” (“constipation”)Pelvic pain, and some types of vulvodynia and interstitial cystitisOrgan prolapse Conclusions Organ prolapse and symptoms are related, and both are mainly caused by laxity in the four main suspensory ligaments and perineal body. Restoration of ligament/fascial length and tension is required to restore anatomy and function. PMID:24578877

  9. Integrated Workforce Modeling System

    NASA Technical Reports Server (NTRS)

    Moynihan, Gary P.

    2000-01-01

    There are several computer-based systems, currently in various phases of development at KSC, which encompass some component, aspect, or function of workforce modeling. These systems may offer redundant capabilities and/or incompatible interfaces. A systems approach to workforce modeling is necessary in order to identify and better address user requirements. This research has consisted of two primary tasks. Task 1 provided an assessment of existing and proposed KSC workforce modeling systems for their functionality and applicability to the workforce planning function. Task 2 resulted in the development of a proof-of-concept design for a systems approach to workforce modeling. The model incorporates critical aspects of workforce planning, including hires, attrition, and employee development.

  10. Research on cultivating medical students’ self-learning ability using teaching system integrated with learning analysis technology

    PubMed Central

    Luo, Hong; Wu, Cheng; He, Qian; Wang, Shi-Yong; Ma, Xiu-Qiang; Wang, Ri; Li, Bing; He, Jia

    2015-01-01

    Along with the advancement of information technology and the era of big data education, using learning process data to provide strategic decision-making in cultivating and improving medical students’ self-learning ability has become a trend in educational research. Educator Abuwen Toffler said once, the illiterates in the future may not be the people not able to read and write, but not capable to know how to learn. Serving as educational institutions cultivating medical students’ learning ability, colleges and universities should not only instruct specific professional knowledge and skills, but also develop medical students’ self-learning ability. In this research, we built a teaching system which can help to restore medical students’ self-learning processes and analyze their learning outcomes and behaviors. To evaluate the effectiveness of the system in supporting medical students’ self-learning, an experiment was conducted in 116 medical students from two grades. The results indicated that problems in self-learning process through this system was consistent with problems raised from traditional classroom teaching. Moreover, the experimental group (using this system) acted better than control group (using traditional classroom teaching) to some extent. Thus, this system can not only help medical students to develop their self-learning ability, but also enhances the ability of teachers to target medical students’ questions quickly, improving the efficiency of answering questions in class. PMID:26550446

  11. Research on cultivating medical students' self-learning ability using teaching system integrated with learning analysis technology.

    PubMed

    Luo, Hong; Wu, Cheng; He, Qian; Wang, Shi-Yong; Ma, Xiu-Qiang; Wang, Ri; Li, Bing; He, Jia

    2015-01-01

    Along with the advancement of information technology and the era of big data education, using learning process data to provide strategic decision-making in cultivating and improving medical students' self-learning ability has become a trend in educational research. Educator Abuwen Toffler said once, the illiterates in the future may not be the people not able to read and write, but not capable to know how to learn. Serving as educational institutions cultivating medical students' learning ability, colleges and universities should not only instruct specific professional knowledge and skills, but also develop medical students' self-learning ability. In this research, we built a teaching system which can help to restore medical students' self-learning processes and analyze their learning outcomes and behaviors. To evaluate the effectiveness of the system in supporting medical students' self-learning, an experiment was conducted in 116 medical students from two grades. The results indicated that problems in self-learning process through this system was consistent with problems raised from traditional classroom teaching. Moreover, the experimental group (using this system) acted better than control group (using traditional classroom teaching) to some extent. Thus, this system can not only help medical students to develop their self-learning ability, but also enhances the ability of teachers to target medical students' questions quickly, improving the efficiency of answering questions in class. PMID:26550446

  12. The Concordat to Support Research Integrity

    ERIC Educational Resources Information Center

    Universities UK, 2012

    2012-01-01

    The concordat to support research integrity sets out five commitments that will provide assurances to government, the wider public and the international community that research in the UK continues to be underpinned by the highest standards of rigour and integrity. Developed in collaboration with the funding and research councils, the Wellcome…

  13. An Integrated Model for Patient Care and Clinical Trials (IMPACT) to support clinical research visit scheduling workflow for future learning health systems.

    PubMed

    Weng, Chunhua; Li, Yu; Berhe, Solomon; Boland, Mary Regina; Gao, Junfeng; Hruby, Gregory W; Steinman, Richard C; Lopez-Jimenez, Carlos; Busacca, Linda; Hripcsak, George; Bakken, Suzanne; Bigger, J Thomas

    2013-08-01

    We describe a clinical research visit scheduling system that can potentially coordinate clinical research visits with patient care visits and increase efficiency at clinical sites where clinical and research activities occur simultaneously. Participatory Design methods were applied to support requirements engineering and to create this software called Integrated Model for Patient Care and Clinical Trials (IMPACT). Using a multi-user constraint satisfaction and resource optimization algorithm, IMPACT automatically synthesizes temporal availability of various research resources and recommends the optimal dates and times for pending research visits. We conducted scenario-based evaluations with 10 clinical research coordinators (CRCs) from diverse clinical research settings to assess the usefulness, feasibility, and user acceptance of IMPACT. We obtained qualitative feedback using semi-structured interviews with the CRCs. Most CRCs acknowledged the usefulness of IMPACT features. Support for collaboration within research teams and interoperability with electronic health records and clinical trial management systems were highly requested features. Overall, IMPACT received satisfactory user acceptance and proves to be potentially useful for a variety of clinical research settings. Our future work includes comparing the effectiveness of IMPACT with that of existing scheduling solutions on the market and conducting field tests to formally assess user adoption. PMID:23684593

  14. An Integrated Model for Patient Care and Clinical Trials (IMPACT) to Support Clinical Research Visit Scheduling Workflow for Future Learning Health Systems

    PubMed Central

    Weng, Chunhua; Li, Yu; Berhe, Solomon; Boland, Mary Regina; Gao, Junfeng; Hruby, Gregory W.; Steinman, Richard C.; Lopez-Jimenez, Carlos; Busacca, Linda; Hripcsak, George; Bakken, Suzanne; Bigger, J Thomas

    2013-01-01

    We describe a clinical research visit scheduling system that can potentially coordinate clinical research visits with patient care visits and increase efficiency at clinical sites where clinical and research activities occur simultaneously. Participatory Design methods were applied to support requirements engineering and to create this software called Integrated Model for Patient Care and Clinical Trials (IMPACT). Using a multi-user constraint satisfaction and resource optimization algorithm, IMPACT automatically synthesizes temporal availability of various research resources and recommends the optimal dates and times for pending research visits. We conducted scenario-based evaluations with 10 clinical research coordinators (CRCs) from diverse clinical research settings to assess the usefulness, feasibility, and user acceptance of IMPACT. We obtained qualitative feedback using semi-structured interviews with the CRCs. Most CRCs acknowledged the usefulness of IMPACT features. Support for collaboration within research teams and interoperability with electronic health records and clinical trial management systems were highly requested features. Overall, IMPACT received satisfactory user acceptance and proves to be potentially useful for a variety of clinical research settings. Our future work includes comparing the effectiveness of IMPACT with that of existing scheduling solutions on the market and conducting field tests to formally assess user adoption. PMID:23684593

  15. Climate change impact and adaptation research requires integrated assessment and farming systems analysis: a case study in the Netherlands

    NASA Astrophysics Data System (ADS)

    Reidsma, Pytrik; Wolf, Joost; Kanellopoulos, Argyris; Schaap, Ben F.; Mandryk, Maryia; Verhagen, Jan; van Ittersum, Martin K.

    2015-04-01

    Rather than on crop modelling only, climate change impact assessments in agriculture need to be based on integrated assessment and farming systems analysis, and account for adaptation at different levels. With a case study for Flevoland, the Netherlands, we illustrate that (1) crop models cannot account for all relevant climate change impacts and adaptation options, and (2) changes in technology, policy and prices have had and are likely to have larger impacts on farms than climate change. While crop modelling indicates positive impacts of climate change on yields of major crops in 2050, a semi-quantitative and participatory method assessing impacts of extreme events shows that there are nevertheless several climate risks. A range of adaptation measures are, however, available to reduce possible negative effects at crop level. In addition, at farm level farmers can change cropping patterns, and adjust inputs and outputs. Also farm structural change will influence impacts and adaptation. While the 5th IPCC report is more negative regarding impacts of climate change on agriculture compared to the previous report, also for temperate regions, our results show that when putting climate change in context of other drivers, and when explicitly accounting for adaptation at crop and farm level, impacts may be less negative in some regions and opportunities are revealed. These results refer to a temperate region, but an integrated assessment may also change perspectives on climate change for other parts of the world.

  16. Feasibility of a Student Unit Record System within the Integrated Postsecondary Education Data System. Research and Development Report. NCES 2005-160

    ERIC Educational Resources Information Center

    Cunningham, Alisa F.; Milam, John

    2005-01-01

    This report examines the feasibility of implementing a student unit record system to replace the student-related components that currently are based on aggregate institution-level data collected as part of the Integrated Postsecondary Education Data System (IPEDS). The feasibility study was initiated by the National Center for Education Statistics…

  17. Integrated Extravehicular Activity Human Research Plan: 2016

    NASA Technical Reports Server (NTRS)

    Abercromby, Andrew F. J.; Ross, Amy J.; Cupples, J. Scott; Rajulu, Sudhakar; Norcross, Jason R.; Chappell, Steven P.

    2016-01-01

    Multiple organizations within NASA and outside of NASA fund and participate in research related to extravehicular activity (EVA). In October 2015, representatives of the EVA Office, the Crew and Thermal Systems Division (CTSD), and the Human Research Program (HRP) at NASA Johnson Space Center agreed on a formal framework to improve multi-year coordination and collaboration in EVA research. At the core of the framework is an Integrated EVA Human Research Plan and a process by which it will be annually reviewed and updated. The over-arching objective of the collaborative framework is to conduct multi-disciplinary cost-effective research that will enable humans to perform EVAs safely, effectively, comfortably, and efficiently, as needed to enable and enhance human space exploration missions. Research activities must be defined, prioritized, planned and executed to comprehensively address the right questions, avoid duplication, leverage other complementary activities where possible, and ultimately provide actionable evidence-based results in time to inform subsequent tests, developments and/or research activities. Representation of all appropriate stakeholders in the definition, prioritization, planning and execution of research activities is essential to accomplishing the over-arching objective. A formal review of the Integrated EVA Human Research Plan will be conducted annually. External peer review of all HRP EVA research activities including compilation and review of published literature in the EVA Evidence Report is will also continue at a frequency determined by HRP management. Coordination with stakeholders outside of the EVA Office, CTSD, and HRP is already in effect on a study-by-study basis; closer coordination on multi-year planning with other EVA stakeholders including academia is being actively pursued. Details of the current Integrated EVA Human Research Plan are presented including description of ongoing and planned research activities in the areas of

  18. Integrated fluorescence analysis system

    DOEpatents

    Buican, Tudor N.; Yoshida, Thomas M.

    1992-01-01

    An integrated fluorescence analysis system enables a component part of a sample to be virtually sorted within a sample volume after a spectrum of the component part has been identified from a fluorescence spectrum of the entire sample in a flow cytometer. Birefringent optics enables the entire spectrum to be resolved into a set of numbers representing the intensity of spectral components of the spectrum. One or more spectral components are selected to program a scanning laser microscope, preferably a confocal microscope, whereby the spectrum from individual pixels or voxels in the sample can be compared. Individual pixels or voxels containing the selected spectral components are identified and an image may be formed to show the morphology of the sample with respect to only those components having the selected spectral components. There is no need for any physical sorting of the sample components to obtain the morphological information.

  19. Advanced Integrated Traction System

    SciTech Connect

    Greg Smith; Charles Gough

    2011-08-31

    The United States Department of Energy elaborates the compelling need for a commercialized competitively priced electric traction drive system to proliferate the acceptance of HEVs, PHEVs, and FCVs in the market. The desired end result is a technically and commercially verified integrated ETS (Electric Traction System) product design that can be manufactured and distributed through a broad network of competitive suppliers to all auto manufacturers. The objectives of this FCVT program are to develop advanced technologies for an integrated ETS capable of 55kW peak power for 18 seconds and 30kW of continuous power. Additionally, to accommodate a variety of automotive platforms the ETS design should be scalable to 120kW peak power for 18 seconds and 65kW of continuous power. The ETS (exclusive of the DC/DC Converter) is to cost no more than $660 (55kW at $12/kW) to produce in quantities of 100,000 units per year, should have a total weight less than 46kg, and have a volume less than 16 liters. The cost target for the optional Bi-Directional DC/DC Converter is $375. The goal is to achieve these targets with the use of engine coolant at a nominal temperature of 105C. The system efficiency should exceed 90% at 20% of rated torque over 10% to 100% of maximum speed. The nominal operating system voltage is to be 325V, with consideration for higher voltages. This project investigated a wide range of technologies, including ETS topologies, components, and interconnects. Each technology and its validity for automotive use were verified and then these technologies were integrated into a high temperature ETS design that would support a wide variety of applications (fuel cell, hybrids, electrics, and plug-ins). This ETS met all the DOE 2010 objectives of cost, weight, volume and efficiency, and the specific power and power density 2015 objectives. Additionally a bi-directional converter was developed that provides charging and electric power take-off which is the first step

  20. Symmetry and quaternionic integrable systems

    NASA Astrophysics Data System (ADS)

    Gaeta, G.; Rodríguez, M. A.

    2015-01-01

    Given a hyperkahler manifold M, the hyperkahler structure defines a triple of symplectic structures on M; with these, a triple of Hamiltonians defines a so-called hyperHamiltonian dynamical system on M. These systems are integrable when can be mapped to a system of quaternionic oscillators. We discuss the symmetry of integrable hyperHamiltonian systems, i.e. quaternionic oscillators, and conversely how these symmetries characterize, at least in the Euclidean case, integrable hyperHamiltonian systems.

  1. Traditional medicine: past, present and future research and development prospects and integration in the National Health System of Cameroon.

    PubMed

    Fokunang, C N; Ndikum, V; Tabi, O Y; Jiofack, R B; Ngameni, B; Guedje, N M; Tembe-Fokunang, E A; Tomkins, P; Barkwan, S; Kechia, F; Asongalem, E; Ngoupayou, J; Torimiro, N J; Gonsu, K H; Sielinou, V; Ngadjui, B T; Angwafor, F; Nkongmeneck, A; Abena, O M; Ngogang, J; Asonganyi, T; Colizzi, V; Lohoue, J; Kamsu-Kom

    2011-01-01

    Traditional medicine refers to health practices, approaches, knowledge and beliefs incorporating plant, animal and mineral based medicines, spiritual therapies, manual techniques and exercises, applied singularly or in combination to treat, diagnose and prevent illnesses or maintain well-being. In the last decade traditional medicine has become very popular in Cameroon, partly due to the long unsustainable economic situation in the country. The high cost of drugs and increase in drug resistance to common diseases like malaria, bacteria infections and other sexually transmitted diseases has caused the therapeutic approach to alternative traditional medicine as an option for concerted search for new chemical entities (NCE). The World Health Organisation (WHO) in collaboration with the Cameroon Government has put in place a strategic platform for the practice and development of TM in Cameroon. This platform aims at harmonizing the traditional medicine practice in the country, create a synergy between TM and modern medicine and to institutionalize a more harmonized integrated TM practices by the year 2012 in Cameroon. An overview of the practice of TM past, present and future perspectives that underpins the role in sustainable poverty alleviation has been discussed. This study gives an insight into the strategic plan and road map set up by the Government of Cameroon for the organisational framework and research platform for the practice and development of TM, and the global partnership involving the management of TM in the country. PMID:22468007

  2. Hawaii integrated biofuels research program, phase 1

    NASA Astrophysics Data System (ADS)

    Takahashi, Patrick K.

    1989-10-01

    Hawaii provides a unique environment for production of biomass resources that can be converted into renewable energy products. The purpose of this work is to evaluate the potential of several biomass resources, including sugarcane, eucalyptus, and leucaena, particularly for utilization in thermochemical conversion processes to produce liquid or gaseous transportation fuels. This research program supports ongoing efforts of the Biofuels and Municipal Solid Waste Technology (BMWT) Program of the Department of Energy (DOE) and has goals that are consistent with BMWT. The Hawaii Natural Energy Institute (HNEI) work completed here consists of research activities that support two of the five renewable fuel cycles being pursued by DOE researchers. The results are directly applicable in the American territories throughout the Pacific Basin and the Caribbean, and also to many parts of the United States and worldwide. The Hawaii Integrated Biofuels Research Program is organized into the following six research tasks, which are presented as appendices in report form: Biomass Resource Assessment and System Modeling (Task 1); Bioenergy Tree Research (Task 2); Breeding, Culture, and Selection of Tropical Grasses for Increased Energy Potential (Task 3); Study of Eucalyptus Plantations for Energy Production in Hawaii (Task 4); Fundamental Solvolysis Research (Task 5); and Effects of Feedstock Composition on Pyrolysis Products (Task 6).

  3. Arcjet system integration development

    NASA Technical Reports Server (NTRS)

    Zafran, Sidney

    1994-01-01

    Compatibility between an arcjet propulsion system and a communications satellite was verified by testing a Government-furnished, 1.4 kW hydrazine arcjet system with the FLTSATCOM qualification model satellite in a 9.1-meter (30-foot) diameter thermal-vacuum test chamber. Background pressure was maintained at 10(exp -5) torr during arcjet operation by cryopumping the thruster exhaust with an array of 5 K liquid helium cooled panels. Power for the arcjet system was obtained from the FLTSATCOM battery simulator. Spacecraft telemetry was monitored during each thruster firing period. No changes in telemetry data attributable to arcjet operation were detected in any of the tests. Electromagnetic compatibility data obtained included radiated emission measurements, conducted emission measurements, and cable coupling measurements. Significant noise was observed at lower frequencies. Above 500 MHz, radiated emissions were generally within limits, indicating that communication links at S-band and higher frequencies will not be affected. Other test data taken with a diagnostic array of calorimeters, radiometers, witness plates, and a residual gas analyzer evidenced compatible operation, and added to the data base for arcjet system integration. Two test series were conducted. The first series only included the arcjet and diagnostic array operating at approximately 0.1 torr background pressure. The second series added the qualification model spacecraft, a solar panel, and the helium cryopanels. Tests were conducted at 0.1 torr and 10(exp-5) torr. The arcjet thruster was canted 20 degrees relative to the solar panel axis, typical of the configuration used for stationkeeping thrusters on geosynchronous communications satellites.

  4. Arcjet system integration development

    NASA Astrophysics Data System (ADS)

    Zafran, Sidney

    1994-03-01

    Compatibility between an arcjet propulsion system and a communications satellite was verified by testing a Government-furnished, 1.4 kW hydrazine arcjet system with the FLTSATCOM qualification model satellite in a 9.1-meter (30-foot) diameter thermal-vacuum test chamber. Background pressure was maintained at 10(exp -5) torr during arcjet operation by cryopumping the thruster exhaust with an array of 5 K liquid helium cooled panels. Power for the arcjet system was obtained from the FLTSATCOM battery simulator. Spacecraft telemetry was monitored during each thruster firing period. No changes in telemetry data attributable to arcjet operation were detected in any of the tests. Electromagnetic compatibility data obtained included radiated emission measurements, conducted emission measurements, and cable coupling measurements. Significant noise was observed at lower frequencies. Above 500 MHz, radiated emissions were generally within limits, indicating that communication links at S-band and higher frequencies will not be affected. Other test data taken with a diagnostic array of calorimeters, radiometers, witness plates, and a residual gas analyzer evidenced compatible operation, and added to the data base for arcjet system integration. Two test series were conducted. The first series only included the arcjet and diagnostic array operating at approximately 0.1 torr background pressure. The second series added the qualification model spacecraft, a solar panel, and the helium cryopanels. Tests were conducted at 0.1 torr and 10(exp-5) torr. The arcjet thruster was canted 20 degrees relative to the solar panel axis, typical of the configuration used for stationkeeping thrusters on geosynchronous communications satellites.

  5. Integrated Management Tracking System

    Energy Science and Technology Software Center (ESTSC)

    2000-03-30

    The Integrated Management Tracking System (IMTS) is a "Web Enabled" Client/Server Business application that provides for the Identification and Resolution of commitments, situations, events and problems. The IMTS engine is written with Microsoft Active Server Pages (ASP) for IIS4. The system provides for reporting, entering, editing, closing and administration over a Intranet, Extranet or Internet. This Application facilitates: Electronic assignment, acceptance and tracking to completion. Email notifications of assigned action. Establishment of Due Dates. Electronicmore » search and retrieval based on keywords in combination with user specified database parameters (Document Type, Date Ranges, etc.). Coded for Trending and Reporting. User selected reports. Various levels of access for reports and administration. The "Server" side of this application consists of a Microsoft Access database running on a NT Server with Internet Information Server (IIS). As the "Client" side of the application runs on any Web browser, this solution is a cost effective, user friendly application that lends itself to organizations not physically colocated in one location providing information immediately available to everyone at once.« less

  6. Integrated Management Tracking System

    SciTech Connect

    Garrett, Terrance

    2000-03-30

    The Integrated Management Tracking System (IMTS) is a "Web Enabled" Client/Server Business application that provides for the Identification and Resolution of commitments, situations, events and problems. The IMTS engine is written with Microsoft Active Server Pages (ASP) for IIS4. The system provides for reporting, entering, editing, closing and administration over a Intranet, Extranet or Internet. This Application facilitates: Electronic assignment, acceptance and tracking to completion. Email notifications of assigned action. Establishment of Due Dates. Electronic search and retrieval based on keywords in combination with user specified database parameters (Document Type, Date Ranges, etc.). Coded for Trending and Reporting. User selected reports. Various levels of access for reports and administration. The "Server" side of this application consists of a Microsoft Access database running on a NT Server with Internet Information Server (IIS). As the "Client" side of the application runs on any Web browser, this solution is a cost effective, user friendly application that lends itself to organizations not physically colocated in one location providing information immediately available to everyone at once.

  7. Integrated multisensor perimeter detection systems

    NASA Astrophysics Data System (ADS)

    Kent, P. J.; Fretwell, P.; Barrett, D. J.; Faulkner, D. A.

    2007-10-01

    The report describes the results of a multi-year programme of research aimed at the development of an integrated multi-sensor perimeter detection system capable of being deployed at an operational site. The research was driven by end user requirements in protective security, particularly in threat detection and assessment, where effective capability was either not available or prohibitively expensive. Novel video analytics have been designed to provide robust detection of pedestrians in clutter while new radar detection and tracking algorithms provide wide area day/night surveillance. A modular integrated architecture based on commercially available components has been developed. A graphical user interface allows intuitive interaction and visualisation with the sensors. The fusion of video, radar and other sensor data provides the basis of a threat detection capability for real life conditions. The system was designed to be modular and extendable in order to accommodate future and legacy surveillance sensors. The current sensor mix includes stereoscopic video cameras, mmWave ground movement radar, CCTV and a commercially available perimeter detection cable. The paper outlines the development of the system and describes the lessons learnt after deployment in a pilot trial.

  8. Integrative NMR for biomolecular research.

    PubMed

    Lee, Woonghee; Cornilescu, Gabriel; Dashti, Hesam; Eghbalnia, Hamid R; Tonelli, Marco; Westler, William M; Butcher, Samuel E; Henzler-Wildman, Katherine A; Markley, John L

    2016-04-01

    NMR spectroscopy is a powerful technique for determining structural and functional features of biomolecules in physiological solution as well as for observing their intermolecular interactions in real-time. However, complex steps associated with its practice have made the approach daunting for non-specialists. We introduce an NMR platform that makes biomolecular NMR spectroscopy much more accessible by integrating tools, databases, web services, and video tutorials that can be launched by simple installation of NMRFAM software packages or using a cross-platform virtual machine that can be run on any standard laptop or desktop computer. The software package can be downloaded freely from the NMRFAM software download page ( http://pine.nmrfam.wisc.edu/download_packages.html ), and detailed instructions are available from the Integrative NMR Video Tutorial page ( http://pine.nmrfam.wisc.edu/integrative.html ). PMID:27023095

  9. Clinical Data Miner: An Electronic Case Report Form System With Integrated Data Preprocessing and Machine-Learning Libraries Supporting Clinical Diagnostic Model Research

    PubMed Central

    Van den Bosch, Thierry; De Moor, Bart; Timmerman, Dirk

    2014-01-01

    Background Using machine-learning techniques, clinical diagnostic model research extracts diagnostic models from patient data. Traditionally, patient data are often collected using electronic Case Report Form (eCRF) systems, while mathematical software is used for analyzing these data using machine-learning techniques. Due to the lack of integration between eCRF systems and mathematical software, extracting diagnostic models is a complex, error-prone process. Moreover, due to the complexity of this process, it is usually only performed once, after a predetermined number of data points have been collected, without insight into the predictive performance of the resulting models. Objective The objective of the study of Clinical Data Miner (CDM) software framework is to offer an eCRF system with integrated data preprocessing and machine-learning libraries, improving efficiency of the clinical diagnostic model research workflow, and to enable optimization of patient inclusion numbers through study performance monitoring. Methods The CDM software framework was developed using a test-driven development (TDD) approach, to ensure high software quality. Architecturally, CDM’s design is split over a number of modules, to ensure future extendability. Results The TDD approach has enabled us to deliver high software quality. CDM’s eCRF Web interface is in active use by the studies of the International Endometrial Tumor Analysis consortium, with over 4000 enrolled patients, and more studies planned. Additionally, a derived user interface has been used in six separate interrater agreement studies. CDM's integrated data preprocessing and machine-learning libraries simplify some otherwise manual and error-prone steps in the clinical diagnostic model research workflow. Furthermore, CDM's libraries provide study coordinators with a method to monitor a study's predictive performance as patient inclusions increase. Conclusions To our knowledge, CDM is the only eCRF system

  10. Integrated system checkout report

    SciTech Connect

    Not Available

    1991-08-14

    The planning and preparation phase of the Integrated Systems Checkout Program (ISCP) was conducted from October 1989 to July 1991. A copy of the ISCP, DOE-WIPP 90--002, is included in this report as an appendix. The final phase of the Checkout was conducted from July 10, 1991, to July 23, 1991. This phase exercised all the procedures and equipment required to receive, emplace, and retrieve contact handled transuranium (CH TRU) waste filled dry bins. In addition, abnormal events were introduced to simulate various equipment failures, loose surface radioactive contamination events, and personnel injury. This report provides a detailed summary of each days activities during this period. Qualification of personnel to safely conduct the tasks identified in the procedures and the abnormal events were verified by observers familiar with the Bin-Scale CH TRU Waste Test requirements. These observers were members of the staffs of Westinghouse WID Engineering, QA, Training, Health Physics, Safety, and SNL. Observers representing a number of DOE departments, the state of new Mexico, and the Defense Nuclear Facilities Safety Board observed those Checkout activities conducted during the period from July 17, 1991, to July 23, 1991. Observer comments described in this report are those obtained from the staff member observers. 1 figs., 1 tab.

  11. Systems Engineering and Integration for Technology Programs

    NASA Technical Reports Server (NTRS)

    Kennedy, Kruss J.

    2006-01-01

    The Architecture, Habitability & Integration group (AH&I) is a system engineering and integration test team within the NASA Crew and Thermal Systems Division (CTSD) at Johnson Space Center. AH&I identifies and resolves system-level integration issues within the research and technology development community. The timely resolution of these integration issues is fundamental to the development of human system requirements and exploration capability. The integration of the many individual components necessary to construct an artificial environment is difficult. The necessary interactions between individual components and systems must be approached in a piece-wise fashion to achieve repeatable results. A formal systems engineering (SE) approach to define, develop, and integrate quality systems within the life support community has been developed. This approach will allow a Research & Technology Program to systematically approach the development, management, and quality of technology deliverables to the various exploration missions. A tiered system engineering structure has been proposed to implement best systems engineering practices across all development levels from basic research to working assemblies. These practices will be implemented through a management plan across all applicable programs, projects, elements and teams. While many of the engineering practices are common to other industries, the implementation is specific to technology development. An accounting of the systems engineering management philosophy will be discussed and the associated programmatic processes will be presented.

  12. Integrated Systems Health Management for Intelligent Systems

    NASA Technical Reports Server (NTRS)

    Figueroa, Fernando; Melcher, Kevin

    2011-01-01

    The implementation of an integrated system health management (ISHM) capability is fundamentally linked to the management of data, information, and knowledge (DIaK) with the purposeful objective of determining the health of a system. Management implies storage, distribution, sharing, maintenance, processing, reasoning, and presentation. ISHM is akin to having a team of experts who are all individually and collectively observing and analyzing a complex system, and communicating effectively with each other in order to arrive at an accurate and reliable assessment of its health. In this chapter, concepts, procedures, and approaches are presented as a foundation for implementing an ISHM capability relevant to intelligent systems. The capability stresses integration of DIaK from all elements of a system, emphasizing an advance toward an on-board, autonomous capability. Both ground-based and on-board ISHM capabilities are addressed. The information presented is the result of many years of research, development, and maturation of technologies, and of prototype implementations in operational systems.

  13. Autonomous power system: Integrated scheduling

    NASA Technical Reports Server (NTRS)

    Ringer, Mark J.

    1992-01-01

    The Autonomous Power System (APS) project at NASA Lewis Research Center is designed to demonstrate the abilities of integrated intelligent diagnosis, control and scheduling techniques to space power distribution hardware. The project consists of three elements: the Autonomous Power Expert System (APEX) for fault diagnosis, isolation, and recovery (FDIR), the Autonomous Intelligent Power Scheduler (AIPS) to determine system configuration, and power hardware (Brassboard) to simulate a space-based power system. Faults can be introduced into the Brassboard and in turn, be diagnosed and corrected by APEX and AIPS. The Autonomous Intelligent Power Scheduler controls the execution of loads attached to the Brassboard. Each load must be executed in a manner that efficiently utilizes available power and satisfies all load, resource, and temporal constraints. In the case of a fault situation on the Brassboard, AIPS dynamically modifies the existing schedule in order to resume efficient operation conditions. A database is kept of the power demand, temporal modifiers, priority of each load, and the power level of each source. AIPS uses a set of heuristic rules to assign start times and resources to each load based on load and resource constraints. A simple improvement engine based upon these heuristics is also available to improve the schedule efficiency. This paper describes the operation of the Autonomous Intelligent Power Scheduler as a single entity, as well as its integration with APEX and the Brassboard. Future plans are discussed for the growth of the Autonomous Intelligent Power Scheduler.

  14. Integrating CHAT and Action Research

    ERIC Educational Resources Information Center

    Wells, Gordon

    2011-01-01

    The question as to how action research (AR) is related to cultural-historical activity theory (CHAT) is not answerable in categorical terms. Both CHAT and AR have been variously interpreted and much depends on the individual biographies of those who pronounce on their relationship. The aim of this paper is to show how action research, conducted…

  15. PROFESSIONAL INTEGRATION AND CLINICAL RESEARCH.

    ERIC Educational Resources Information Center

    WARD, TED W.

    THE RATIONALE OF A CLINICAL APPROACH TO RESEARCH ON TEACHER BEHAVIOR IS SET FORTH TOGETHER WITH INDICATION OF DIFFICULTIES. IN ONE CLINICAL STUDY, RECORDS OF FOCUSED OBSERVATIONS OF TEACHER BEHAVIOR WERE REVIEWED BY A SPECIALIST IN LEARNING AND A SPECIALIST IN SOCIAL PSYCHOLOGY IN RELATION TO RESEARCH FROM THESE FIELDS. TEACHER DECISIONS PROVED…

  16. A Digital Architecture for a Network-Based Learning Health System: Integrating Chronic Care Management, Quality Improvement, and Research

    PubMed Central

    Marsolo, Keith; Margolis, Peter A.; Forrest, Christopher B.; Colletti, Richard B.; Hutton, John J.

    2015-01-01

    Introduction: We collaborated with the ImproveCareNow Network to create a proof-of-concept architecture for a network-based Learning Health System. This collaboration involved transitioning an existing registry to one that is linked to the electronic health record (EHR), enabling a “data in once” strategy. We sought to automate a series of reports that support care improvement while also demonstrating the use of observational registry data for comparative effectiveness research. Description of Architecture: We worked with three leading EHR vendors to create EHR-based data collection forms. We automated many of ImproveCareNow’s analytic reports and developed an application for storing protected health information and tracking patient consent. Finally, we deployed a cohort identification tool to support feasibility studies and hypothesis generation. There is ongoing uptake of the system. To date, 31 centers have adopted the EHR-based forms and 21 centers are uploading data to the registry. Usage of the automated reports remains high and investigators have used the cohort identification tools to respond to several clinical trial requests. Suggestions for Future Use: The current process for creating EHR-based data collection forms requires groups to work individually with each vendor. A vendor-agnostic model would allow for more rapid uptake. We believe that interfacing network-based registries with the EHR would allow them to serve as a source of decision support. Additional standards are needed in order for this vision to be achieved, however. Conclusions: We have successfully implemented a proof-of-concept Learning Health System while providing a foundation on which others can build. We have also highlighted opportunities where sponsors could help accelerate progress. PMID:26357665

  17. TH-C-17A-12: Integrated CBCT and Optical Tomography System On-Board a Small Animal Radiation Research Platform (SARRP)

    SciTech Connect

    Wang, K; Zhang, B; Eslami, S; Iordachita, I; Wong, J; Patterson, M

    2014-06-15

    Purpose: We present a newly developed on-board optical tomography system for SARRP. Innovative features include the compact design and fast acquisition optical method to perform 3D soft tissue radiation guidance. Because of the on-board feature and the combination of the CBCT, diffusive optical tomography (DOT), bioluminescence and fluorescence tomography (BLT and FT), this integrated system is expected to provide more accurate soft tissue guidance than an off-line system as well as highly sensitive functional imaging in preclinical research. Methods: Images are acquired in the order of CBCT, DOT and then BLT/FT, where the SARRP CBCT and DOT are used to provide the anatomical and optical properties information to enhance the subsequent BLT/FT optical reconstruction. The SARRP stage is redesigned to include 9 imbedded optical fibers in contact with the animal's skin. These fibers, connected to a white light lamp or laser, serve as the light sources for the DOT or FT, respectively. A CCD camera with f/1.4 lens and multi-spectral filter set is used as the optical detector and is mounted on a portable cart ready to dock into the SARRP. No radiation is delivered during optical image acquisition. A 3-way mirror system capable of 180 degree rotation around the animal reflects the optical signal to the camera at multiple projection angles. A special black-painted dome covers the stage and provides the light shielding. Results: Spontaneous metastatic bioluminescent liver and lung tumor models will be used to validate the 3D BLT reconstruction. To demonstrate the capability of our FT system, GastroSense750 fluorescence agent will be used to imaging the mouse stomach and intestinal region in 3D. Conclusion: We expect that this integrated CBCT and optical tomography on-board a SARRP will present new research opportunities for pre-clinical radiation research. Supported by NCI RO1-CA 158100.

  18. Vehicle Systems Integration Laboratory Accelerates Powertrain Development

    SciTech Connect

    2014-04-15

    ORNL's Vehicle Systems Integration (VSI) Laboratory accelerates the pace of powertrain development by performing prototype research and characterization of advanced systems and hardware components. The VSI Lab is capable of accommodating a range of platforms from advanced light-duty vehicles to hybridized Class 8 powertrains with the goals of improving overall system efficiency and reducing emissions.

  19. Vehicle Systems Integration Laboratory Accelerates Powertrain Development

    ScienceCinema

    None

    2014-06-25

    ORNL's Vehicle Systems Integration (VSI) Laboratory accelerates the pace of powertrain development by performing prototype research and characterization of advanced systems and hardware components. The VSI Lab is capable of accommodating a range of platforms from advanced light-duty vehicles to hybridized Class 8 powertrains with the goals of improving overall system efficiency and reducing emissions.

  20. Noncommutative integrable systems and quasideterminants

    SciTech Connect

    Hamanaka, Masashi

    2010-03-08

    We discuss extension of soliton theories and integrable systems into noncommutative spaces. In the framework of noncommutative integrable hierarchy, we give infinite conserved quantities and exact soliton solutions for many noncommutative integrable equations, which are represented in terms of Strachan's products and quasi-determinants, respectively. We also present a relation to an noncommutative anti-self-dual Yang-Mills equation, and make comments on how 'integrability' should be considered in noncommutative spaces.

  1. French registry of workers handling engineered nanomaterials as an instrument of integrated system for surveillance and research

    NASA Astrophysics Data System (ADS)

    Guseva Canu, I.; Boutou-Kempf, O.; Delabre, L.; Ducamp, S.; Iwatsubo, Y.; Marchand, J. L.; Imbernon, E.

    2013-04-01

    Despite the lack of data on the human health potential risks related to the engineered nanomaterials (ENM) exposure, ENM handling spreads in industry. The French government officially charged the InVS to develop an epidemiological surveillance of workers occupationally exposed to ENM. An initial surveillance plan was proposed on the basis of literature review and discussions with national and international ENM and occupational safety and health (OSH) experts. In site investigations and technical visits were then carried out to build an adequate surveillance system and to assess its feasibility. The current plan consists of a multi-step methodology where exposure registry construction is paramount. Workers potentially exposed to carbon nanotubes (CNT) or nanometric titanium dioxide (TiO2) will be identified using a 3-level approach: 1-identification and selection of companies concerned with ENM exposure (based on compulsory declaration and questionnaires), 2-in site exposure assessment and identification of the jobs/tasks with ENM exposure (based on job-expose matrix, further supplemented with measurements), and 3-identification of workers concerned. Data of interest will be collected by questionnaire. Companies and workers inclusion questionnaires are designed and currently under validation. This registration is at the moment planned for three years but could be extended and include other ENM. A prospective cohort study will be established from this registry, to pursue surveillance objectives and serve as an infrastructure for performing epidemiological and panel studies with specific research objectives.

  2. Research and Practice: We Can Integrate Them.

    ERIC Educational Resources Information Center

    Casanova, Ursula

    1989-01-01

    The teacher-researcher split must be overcome to help improve schools and instruction. Research and practice integration will involve attitudinal changes accomplished through specific activities to increase teacher reflection, familiarity with the knowledge base, inquiry, and collegiality. Researchers, teacher-training institutions, and school…

  3. Robust Integrated Neurocontroller for Complex Dynamic Systems

    NASA Technical Reports Server (NTRS)

    Zein-Sabatto, S.; Marpaka, D.; Hwang, W.

    1996-01-01

    The goal of this research effort is to develop an integrated control software environment for the purpose of creating an intelligent neurocontrol system. The system will be capable of estimating states, identifying parameters, diagnosing conditions, planning control strategies, and producing intelligent control actions. The distinct features of such control system are: adaptability and on-line learning capability. The proposed system will be flexible to allow structure adaptability to account for changes in the dynamic system such as: sensory failures and/or component degradations. The developed system should learn system uncertainties and changes, as they occur, while maintaining minimal control level on the dynamic system. The research activities set to achieve the research objective are summarized by the following general items: (1) Development of a system identifier or diagnostic system, (2) Development of a robust neurocontroller system, and 3. Integration of above systems to create a Robust Integrated Control system (RIC-system). Two contrary approaches are investigated in this research: classical (traditional) design approach, and the simultaneous design approach. However, in both approaches neural network is the base for the development of different functions of the system. The two resulting designs will be tested and simulation results will be compared for better possible implementation.

  4. Robust integrated neurocontroller for complex dynamic systems

    NASA Technical Reports Server (NTRS)

    Zein-Sabbato, S.; Marpaka, D.; Hwang, W.

    1995-01-01

    The goal of this research effort is to develop an integrated control software environment for the purpose of creating an intelligent neurocontrol system. The system will be capable of estimating states, identifying parameters, diagnosing conditions, planning control strategies, and producing intelligent control actions. The distinct features of such control system are adaptability and on-line learning capability. The proposed system will be flexible to allow structure adaptability to account for changes in the dynamic system such as sensory failures and/or component degradations. The developed system should learn system uncertainties and changes, as they occur, while maintaining minimal control level on the dynamic system. The research activities set to achieve the research objective are summarized by the following general items: (1) Development of a system identifier or diagnostic system; (2) Development of a robust neurocontroller system, and; (3) Integration of above systems to create a robust Integration Control system (RIC-system). Two contrary approaches are investigated in this research: classical (traditional) design approach, and the simultaneous design approach. However, in both approaches neural network is the base for the development of different functions of the system. The two resulting designs will be tested and simulation results will be compared for better possible implementation.

  5. Central Fan Integrated Ventilation Systems

    SciTech Connect

    2009-05-12

    This information sheet describes one example of a ventilation system design, a central fan integrated supply (CFIS) system, a mechanical ventilation and pollutant source control to ensure that there is reasonable indoor air quality inside the house.

  6. Energy Systems Integration Facility Overview

    ScienceCinema

    Arvizu, Dan; Chistensen, Dana; Hannegan, Bryan; Garret, Bobi; Kroposki, Ben; Symko-Davies, Martha; Post, David; Hammond, Steve; Kutscher, Chuck; Wipke, Keith

    2014-06-10

    The U.S. Department of Energy's Energy Systems Integration Facility (ESIF) is located at the National Renewable Energy Laboratory is the right tool, at the right time... a first-of-its-kind facility that addresses the challenges of large-scale integration of clean energy technologies into the energy systems that power the nation.

  7. Energy Systems Integration Facility Overview

    SciTech Connect

    Arvizu, Dan; Chistensen, Dana; Hannegan, Bryan; Garret, Bobi; Kroposki, Ben; Symko-Davies, Martha; Post, David; Hammond, Steve; Kutscher, Chuck; Wipke, Keith

    2014-02-28

    The U.S. Department of Energy's Energy Systems Integration Facility (ESIF) is located at the National Renewable Energy Laboratory is the right tool, at the right time... a first-of-its-kind facility that addresses the challenges of large-scale integration of clean energy technologies into the energy systems that power the nation.

  8. The integrated project NF-PRO: recent advances in European research on the near-field system

    SciTech Connect

    Sneyers, Alain; Grambow, Bernd; Aranyossy, Jean-Francois; Johnson, Lawrence

    2007-07-01

    The Integrated Project NF-PRO (Sixth Framework Programme by the European Commission) investigates key-processes in the near-field of a geological repository for the disposal of high-level vitrified waste and spent fuel. The paper discusses the project scope and content and gives a summary overview of advances made by NF-PRO. (authors)

  9. Supporting Theory Building in Integrated Services Research

    ERIC Educational Resources Information Center

    Robinson, Mark; Atkinson, Mary; Downing, Dick

    2008-01-01

    This literature review was commissioned by the National Foundation for Educational Research (NFER) to draw together current and recent studies of integrated working, in order to build an overview of the theories and models of such working. The review is important for current work on evaluating the early impact of integrated children's services and…

  10. Integration: An Agenda for Developmental Research.

    ERIC Educational Resources Information Center

    Scholnick, Ellin Kofsky

    2001-01-01

    Finds Bloom and Tinker's description and measurement of active, integrated, and situated children to be a credible scientifically rigorous paradigm for language acquisition research. Highlights their use of the naturalistic, observational method to understand the changing patterns of integration and use of multifaceted abilities in child language…

  11. Using Scholarship To Integrate Teaching and Research.

    ERIC Educational Resources Information Center

    McKenna, Judy; Bickle, Marianne; Carroll, Jan B.

    2002-01-01

    A merchandising course illustrates Boyer's four stages of scholarship--discovery, integration, application, and teaching--and adds a fifth: outcome (production of a scholarly product). The model is a means of integrating teaching and research in family and consumer sciences education. (SK)

  12. Seeking an international dialogue on research integrity.

    PubMed

    Aschwanden, Christie

    2007-10-01

    Scientific misconduct is a global problem, yet protocols for addressing it remain highly fragmented and uneven. A conference held last month in Lisbon aimed to encourage international efforts to promote research integrity and to prevent misconduct. PMID:17923078

  13. Integrated Learning Management Systems

    ERIC Educational Resources Information Center

    Clark, Sharon; Cossarin, Mary; Doxsee, Harry; Schwartz, Linda

    2004-01-01

    Four integrated learning management packages were reviewed: "CentraOne", "IntraLearn", "Lyceum", and "Silicon Chalk". These products provide different combinations of synchronous and asynchronous tools. The current report examines the products in relation to their specific value for distance educators and students.

  14. Integrated roof wind energy system

    NASA Astrophysics Data System (ADS)

    Suma, A. B.; Ferraro, R. M.; Dano, B.; Moonen, S. P. G.

    2012-10-01

    Wind is an attractive renewable source of energy. Recent innovations in research and design have reduced to a few alternatives with limited impact on residential construction. Cost effective solutions have been found at larger scale, but storage and delivery of energy to the actual location it is used, remain a critical issue. The Integrated Roof Wind Energy System is designed to overcome the current issues of urban and larger scale renewable energy system. The system is built up by an axial array of skewed shaped funnels that make use of the Venturi Effect to accelerate the wind flow. This inventive use of shape and geometry leads to a converging air capturing inlet to create high wind mass flow and velocity toward a vertical-axis wind turbine in the top of the roof for generation of a relatively high amount of energy. The methods used in this overview of studies include an array of tools from analytical modelling, PIV wind tunnel testing, and CFD simulation studies. The results define the main design parameters for an efficient system, and show the potential for the generation of high amounts of renewable energy with a novel and effective system suited for the built environment.

  15. EPOS: Integrating seismological Research Infrastructures within Europe

    NASA Astrophysics Data System (ADS)

    Eck Van, Torild; Clinton, John; Haslinger, Florian; Michelini, Alberto

    2013-04-01

    Seismological data, products and models are currently produced in Europe within individual countries or research organizations, and with the contribution of coordinating organizations like ORFEUS and EMSC. In spite of these partly scattered resources, significant scientific results are obtained, excellent monitoring and information systems are operational and a huge amount of research quality data is being archived and disseminated. The seismological community, however, realizes that an effective European-scale integration of seismological and related geophysical data, products and models, combined with broad and easy access, is needed to facilitate future top level geoscience, for example, to appropriately harness the technological advancements enabling large scale and near-real time data processing. Here we present the technical concepts and developments within European seismology that will build the next generation of integrated services. Within the EPOS initiative and a number of related projects, where seismology infrastructure and IT developments are merging, in depth discussions are on-going on how to realize an effective integration. Concepts and visions addressing the obviously complex challenges resulting from the current highly distributed facilities and resources in Europe are emerging and are already partly being implemented. We will provide an overview of developments within key EU projects (NERA, VERCE, COOPEUS, EUDAT, REAKT, COMMIT, etc) and demonstrate how these are in coherence with EPOS and other on-going global initiatives. Within seismology current focus is on addressing IT related challenges to a) organize distributed data archives, develop metadata attributes for improved data searching, specifically including quality indicators, and define products from data and/or models, and b) define and create(on-line) monitoring, data access and processing tools. While developments to meet those challenges originate partly from within the community

  16. Intelligent systems technology infrastructure for integrated systems

    NASA Technical Reports Server (NTRS)

    Lum, Henry

    1991-01-01

    A system infrastructure must be properly designed and integrated from the conceptual development phase to accommodate evolutionary intelligent technologies. Several technology development activities were identified that may have application to rendezvous and capture systems. Optical correlators in conjunction with fuzzy logic control might be used for the identification, tracking, and capture of either cooperative or non-cooperative targets without the intensive computational requirements associated with vision processing. A hybrid digital/analog system was developed and tested with a robotic arm. An aircraft refueling application demonstration is planned within two years. Initially this demonstration will be ground based with a follow-on air based demonstration. System dependability measurement and modeling techniques are being developed for fault management applications. This involves usage of incremental solution/evaluation techniques and modularized systems to facilitate reuse and to take advantage of natural partitions in system models. Though not yet commercially available and currently subject to accuracy limitations, technology is being developed to perform optical matrix operations to enhance computational speed. Optical terrain recognition using camera image sequencing processed with optical correlators is being developed to determine position and velocity in support of lander guidance. The system is planned for testing in conjunction with Dryden Flight Research Facility. Advanced architecture technology is defining open architecture design constraints, test bed concepts (processors, multiple hardware/software and multi-dimensional user support, knowledge/tool sharing infrastructure), and software engineering interface issues.

  17. Mediator infrastructure for information integration and semantic data integration environment for biomedical research.

    PubMed

    Grethe, Jeffrey S; Ross, Edward; Little, David; Sanders, Brian; Gupta, Amarnath; Astakhov, Vadim

    2009-01-01

    This paper presents current progress in the development of semantic data integration environment which is a part of the Biomedical Informatics Research Network (BIRN; http://www.nbirn.net) project. BIRN is sponsored by the National Center for Research Resources (NCRR), a component of the National Institutes of Health (NIH). A goal is the development of a cyberinfrastructure for biomedical research that supports advance data acquisition, data storage, data management, data integration, data mining, data visualization, and other computing and information processing services over the Internet. Each participating institution maintains storage of their experimental or computationally derived data. Mediator-based data integration system performs semantic integration over the databases to enable researchers to perform analyses based on larger and broader datasets than would be available from any single institution's data. This paper describes recent revision of the system architecture, implementation, and capabilities of the semantically based data integration environment for BIRN. PMID:19623485

  18. Integrity in Postgraduate Research: The Student Voice.

    PubMed

    Mahmud, Saadia; Bretag, Tracey

    2015-12-01

    There is a limited understanding of the student perspective of integrity in postgraduate research. This is of concern given that 'research trainees' may have a vulnerable position in formal investigations of research misconduct. This paper analyses qualitative data drawn from an Australian online academic integrity survey in a mixed methods research study. This analysis complements the quantitative survey data analysed earlier and sought to explore factors contributing to postgraduate research students' satisfaction with policy and process, the ways institutions can support students' understandings and practice, suggestions for improving breach processes, and students' concerns. We found that integrity training and modelling of ethical behaviour by staff were key factors contributing to students' satisfaction. Students would have liked more 'hands-on' integrity training, accompanied by consistent and transparent enforcement of policy. Respondents expressed concern about the credibility of research output and educational standards. We call for recommendations from the extensive literature on academic integrity policy and practice to be extended to the postgraduate research sphere. PMID:25488333

  19. From Research to Operations: Integrating Components of an Advanced Diagnostic System with an Aspect-Oriented Framework

    NASA Technical Reports Server (NTRS)

    Fletcher, Daryl P.; Alena, Richard L.; Akkawi, Faisal; Duncavage, Daniel P.

    2004-01-01

    This paper presents some of the challenges associated with bringing software projects from the research world into an operationa1 environment. While the core functional components of research-oriented software applications can have great utility in an operational setting, these applications often lack aspects important in an operational environment such as logging and security. Furthermore, these stand-alone applications, sometimes developed in isolation from one another, can produce data products useful to other applications in a software ecosystem.

  20. Data integration in biological research: an overview.

    PubMed

    Lapatas, Vasileios; Stefanidakis, Michalis; Jimenez, Rafael C; Via, Allegra; Schneider, Maria Victoria

    2015-12-01

    Data sharing, integration and annotation are essential to ensure the reproducibility of the analysis and interpretation of the experimental findings. Often these activities are perceived as a role that bioinformaticians and computer scientists have to take with no or little input from the experimental biologist. On the contrary, biological researchers, being the producers and often the end users of such data, have a big role in enabling biological data integration. The quality and usefulness of data integration depend on the existence and adoption of standards, shared formats, and mechanisms that are suitable for biological researchers to submit and annotate the data, so it can be easily searchable, conveniently linked and consequently used for further biological analysis and discovery. Here, we provide background on what is data integration from a computational science point of view, how it has been applied to biological research, which key aspects contributed to its success and future directions. PMID:26336651

  1. Integrating Soil and Crop Research with System Models in the Midwest USA: Purpose and Overview of the Special Issue

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The Nashua experimental site was one of the USDA Management Systems Evaluations (MSEA) sites in 1990s to evaluate agricultural systems and management effects on water quality and crop production in the Midwestern U.S. This site has been used to evaluate several different agricultural management prac...

  2. The GEOSS solution for enabling data interoperability and integrative research.

    PubMed

    Nativi, Stefano; Mazzetti, Paolo; Craglia, Max; Pirrone, Nicola

    2014-03-01

    Global sustainability research requires an integrative research effort underpinned by digital infrastructures (systems) able to harness data and heterogeneous information across disciplines. Digital data and information sharing across systems and applications is achieved by implementing interoperability: a property of a product or system to work with other products or systems, present or future. There are at least three main interoperability challenges a digital infrastructure must address: technological, semantic, and organizational. In recent years, important international programs and initiatives are focusing on such an ambitious objective. This manuscript presents and combines the studies and the experiences carried out by three relevant projects, focusing on the heavy metal domain: Global Mercury Observation System, Global Earth Observation System of Systems (GEOSS), and INSPIRE. This research work recognized a valuable interoperability service bus (i.e., a set of standards models, interfaces, and good practices) proposed to characterize the integrative research cyber-infrastructure of the heavy metal research community. In the paper, the GEOSS common infrastructure is discussed implementing a multidisciplinary and participatory research infrastructure, introducing a possible roadmap for the heavy metal pollution research community to join GEOSS as a new Group on Earth Observation community of practice and develop a research infrastructure for carrying out integrative research in its specific domain. PMID:24243262

  3. Integrating Software for Sample Size Calculations, Data Entry, and Tabulation: Software Demonstration of a System for Survey Research.

    ERIC Educational Resources Information Center

    Lambert, Richard; Flowers, Claudia; Sipe, Theresa; Idleman, Lynda

    This paper discusses three software packages that offer unique features and options that greatly simplify the research package for conducting surveys. The first package, EPSILON, from Resource Group, Ltd. of Dallas (Texas) is designed to perform a variety of sample size calculations covering most of the commonly encountered survey research…

  4. Advanced optical manufacturing digital integrated system

    NASA Astrophysics Data System (ADS)

    Tao, Yizheng; Li, Xinglan; Li, Wei; Tang, Dingyong

    2012-10-01

    It is necessarily to adapt development of advanced optical manufacturing technology with modern science technology development. To solved these problems which low of ration, ratio of finished product, repetition, consistent in big size and high precision in advanced optical component manufacturing. Applied business driven and method of Rational Unified Process, this paper has researched advanced optical manufacturing process flow, requirement of Advanced Optical Manufacturing integrated System, and put forward architecture and key technology of it. Designed Optical component core and Manufacturing process driven of Advanced Optical Manufacturing Digital Integrated System. the result displayed effective well, realized dynamic planning Manufacturing process, information integration improved ratio of production manufactory.

  5. A coordinated research programme to develop methodologies for an integrated approach to improve small scale market oriented dairy systems in developing countries.

    PubMed

    Perera, B M A O

    2007-12-01

    A five-year Coordinated Research Project (CRP) entitled 'Integrated approach for improving small scale market oriented dairy systems' is currently being implemented by the Food and Agriculture Organization and the International Atomic Energy Agency, through their Joint Programme on 'Nuclear Techniques in Food and Agriculture'. The objectives are to (a) identify and prioritize the constraints and opportunities in the selected dairy farms; (b) determine the most important limiting factors; (c) develop intervention strategies; (c) assess the economic impact of the interventions; (d) develop methodologies for recording and demonstrating the economic impact; and (e) promote the adoption and dissemination of proven strategies and methodologies. Fifteen institutes in developing as well as developed countries are participating in the project, through ten research contracts (Bangladesh, Cameroon, Pakistan, Paraguay, Peru, South Africa, Sri Lanka, Tanzania, Tunisia and Venezuela), one technical contract (Peru) and four research agreements (Malaysia, U.K., U.S.A. and Uruguay). The initial phase of the project, which focused on the conduct of Participatory Rural Appraisals and Economic Opportunity Surveys in the countries of the research contract holders, has now been completed. This paper describes the background to the CRP approach and the procedures used for developing, initiating and implementing this project. PMID:18265863

  6. Distributed Access View Integrated Database (DAVID) system

    NASA Technical Reports Server (NTRS)

    Jacobs, Barry E.

    1991-01-01

    The Distributed Access View Integrated Database (DAVID) System, which was adopted by the Astrophysics Division for their Astrophysics Data System, is a solution to the system heterogeneity problem. The heterogeneous components of the Astrophysics problem is outlined. The Library and Library Consortium levels of the DAVID approach are described. The 'books' and 'kits' level is discussed. The Universal Object Typer Management System level is described. The relation of the DAVID project with the Small Business Innovative Research (SBIR) program is explained.

  7. Integrated multiplexed capillary electrophoresis system

    SciTech Connect

    Yeung, Edward S.; Tan, Hongdong

    2002-05-14

    The present invention provides an integrated multiplexed capillary electrophoresis system for the analysis of sample analytes. The system integrates and automates multiple components, such as chromatographic columns and separation capillaries, and further provides a detector for the detection of analytes eluting from the separation capillaries. The system employs multiplexed freeze/thaw valves to manage fluid flow and sample movement. The system is computer controlled and is capable of processing samples through reaction, purification, denaturation, pre-concentration, injection, separation and detection in parallel fashion. Methods employing the system of the invention are also provided.

  8. An integrated multimedia medical information network system.

    PubMed

    Yamamoto, K; Makino, J; Sasagawa, N; Nagira, M

    1998-01-01

    An integrated multimedia medical information network system at Shimane Medical university has been developed to organize medical information generated from each section and provide information services useful for education, research and clinical practice. The report describes the outline of our system. It is designed to serve as a distributed database for electronic medical records and images. We are developing the MML engine that is to be linked to the world wide web (WWW) network system. To the users, this system will present an integrated multimedia representation of the patient records, providing access to both the image and text-based data required for an effective clinical decision making and medical education. PMID:10384445

  9. Energy Systems Integration: A Convergence of Ideas

    SciTech Connect

    Kroposki, B.; Garrett, B.; MacMillan, S.; Rice, B.; Komomua, C.; O'Malley, M.; Zimmerle, D.

    2012-07-01

    Energy systems integration (ESI) enables the effective analysis, design, and control of these interactions and interdependencies along technical, economic, regulatory, and social dimensions. By focusing on the optimization of energy from all systems, across all pathways, and at all scales, we can better understand and make use of the co-benefits that result to increase reliability and performance, reduce cost, and minimize environmental impacts. This white paper discusses systems integration and the research in new control architectures that are optimized at smaller scales but can be aggregated to optimize energy systems at any scale and would allow replicable energy solutions across boundaries of existing and new energy pathways.

  10. Human Systems Integration in the Federal Government

    NASA Technical Reports Server (NTRS)

    Jones, Patricia M.; Graves, Gaye L.; Allard, Terry; Blackhurst, Jack; Fitts, David J.; Peters, Sean; Piccione, Dino; Shattuck, Lawrence G.

    2010-01-01

    Human Systems Integration principles and methods can be used to help integrate people, technology, and organizations in an effective and efficient manner. Over the past decade, a wide range of tools, techniques, and technologies have been developed by federal agencies to achieve significant cost and performance benefits. In this discussion, we will explore trends in military human systems integration and learn about the critical role being played by human performance and effectiveness research. We will also examine case studies on the planning and design of future human space flight vehicles, the national air space system and the first nuclear reactors to be built in the United States in over 30 years. And with an eye toward sustaining the discipline s principles and methods, we ll take a look at educating and training the next generation of human systems integration practitioners.

  11. Health systems integration: state of the evidence

    PubMed Central

    Armitage, Gail D.; Suter, Esther; Oelke, Nelly D.; Adair, Carol E.

    2009-01-01

    Introduction Integrated health systems are considered a solution to the challenge of maintaining the accessibility and integrity of healthcare in numerous jurisdictions worldwide. However, decision makers in a Canadian health region indicated they were challenged to find evidence-based information to assist with the planning and implementation of integrated healthcare systems. Methods A systematic literature review of peer-reviewed literature from health sciences and business databases, and targeted grey literature sources. Results Despite the large number of articles discussing integration, significant gaps in the research literature exist. There was a lack of high quality, empirical studies providing evidence on how health systems can improve service delivery and population health. No universal definition or concept of integration was found and multiple integration models from both the healthcare and business literature were proposed in the literature. The review also revealed a lack of standardized, validated tools that have been systematically used to evaluate integration outcomes. This makes measuring and comparing the impact of integration on system, provider and patient level challenging. Discussion and conclusion Healthcare is likely too complex for a one-size-fits-all integration solution. It is important for decision makers and planners to choose a set of complementary models, structures and processes to create an integrated health system that fits the needs of the population across the continuum of care. However, in order to have evidence available, decision makers and planners should include evaluation for accountability purposes and to ensure a better understanding of the effectiveness and impact of health systems integration. PMID:19590762

  12. Plants in silico: why, why now and what?--an integrative platform for plant systems biology research.

    PubMed

    Zhu, Xin-Guang; Lynch, Jonathan P; LeBauer, David S; Millar, Andrew J; Stitt, Mark; Long, Stephen P

    2016-05-01

    A paradigm shift is needed and timely in moving plant modelling from largely isolated efforts to a connected community endeavour that can take full advantage of advances in computer science and in mechanistic understanding of plant processes. Plants in silico (Psi) envisions a digital representation of layered dynamic modules, linking from gene networks and metabolic pathways through to cellular organization, tissue, organ and whole plant development, together with resource capture and use efficiency in dynamic competitive environments, ultimately allowing a mechanistically rich simulation of the plant or of a community of plants in silico. The concept is to integrate models or modules from different layers of organization spanning from genome to phenome to ecosystem in a modular framework allowing the use of modules of varying mechanistic detail representing the same biological process. Developments in high-performance computing, functional knowledge of plants, the internet and open-source version controlled software make achieving the concept realistic. Open source will enhance collaboration and move towards testing and consensus on quantitative theoretical frameworks. Importantly, Psi provides a quantitative knowledge framework where the implications of a discovery at one level, for example, single gene function or developmental response, can be examined at the whole plant or even crop and natural ecosystem levels. PMID:26523481

  13. Equipment concept design and development plans for microgravity science and applications research on space station: Combustion tunnel, laser diagnostic system, advanced modular furnace, integrated electronics laboratory

    NASA Technical Reports Server (NTRS)

    Uhran, M. L.; Youngblood, W. W.; Georgekutty, T.; Fiske, M. R.; Wear, W. O.

    1986-01-01

    Taking advantage of the microgravity environment of space NASA has initiated the preliminary design of a permanently manned space station that will support technological advances in process science and stimulate the development of new and improved materials having applications across the commercial spectrum. Previous studies have been performed to define from the researcher's perspective, the requirements for laboratory equipment to accommodate microgravity experiments on the space station. Functional requirements for the identified experimental apparatus and support equipment were determined. From these hardware requirements, several items were selected for concept designs and subsequent formulation of development plans. This report documents the concept designs and development plans for two items of experiment apparatus - the Combustion Tunnel and the Advanced Modular Furnace, and two items of support equipment the Laser Diagnostic System and the Integrated Electronics Laboratory. For each concept design, key technology developments were identified that are required to enable or enhance the development of the respective hardware.

  14. Digital system bus integrity

    NASA Technical Reports Server (NTRS)

    Eldredge, Donald; Hitt, Ellis F.

    1987-01-01

    This report summarizes and describes the results of a study of current or emerging multiplex data buses as applicable to digital flight systems, particularly with regard to civil aircraft. Technology for pre-1995 and post-1995 timeframes has been delineated and critiqued relative to the requirements envisioned for those periods. The primary emphasis has been an assured airworthiness of the more prevalent type buses, with attention to attributes such as fault tolerance, environmental susceptibility, and problems under continuing investigation. Additionally, the capacity to certify systems relying on such buses has been addressed.

  15. The Role of Professional Societies in Promoting Integrity in Research

    ERIC Educational Resources Information Center

    Steneck, Nicholas H.

    2003-01-01

    Objectives: To summarize what is known about and to offer suggestions for steps professional societies can take to foster greater integrity in research. Methods: Analysis of research literature on research integrity. Results: Research on research integrity has identified 3 areas for concerns about integrity: 1) research misconduct, 2)…

  16. Integrated Communication Systems.

    ERIC Educational Resources Information Center

    Simpson, Ward

    2003-01-01

    Describes the Internet-based information system that has provided effective communications and reporting for the upgrade to K-12 schools in Scottsdale, Arizona. The Website and software applications created valuable communications in the construction process and improved reporting on progress. (SLD)

  17. Voice integrated systems

    NASA Technical Reports Server (NTRS)

    Curran, P. Mike

    1977-01-01

    The program at Naval Air Development Center was initiated to determine the desirability of interactive voice systems for use in airborne weapon systems crew stations. A voice recognition and synthesis system (VRAS) was developed and incorporated into a human centrifuge. The speech recognition aspect of VRAS was developed using a voice command system (VCS) developed by Scope Electronics. The speech synthesis capability was supplied by a Votrax, VS-5, speech synthesis unit built by Vocal Interface. The effects of simulated flight on automatic speech recognition were determined by repeated trials in the VRAS-equipped centrifuge. The relationship of vibration, G, O2 mask, mission duration, and cockpit temperature and voice quality was determined. The results showed that: (1) voice quality degrades after 0.5 hours with an O2 mask; (2) voice quality degrades under high vibration; and (3) voice quality degrades under high levels of G. The voice quality studies are summarized. These results were obtained with a baseline of 80 percent recognition accuracy with VCS.

  18. An analytical investigation of acquisition techniques and system integration studies for a radar aircraft guidance research facility, phase 2

    NASA Technical Reports Server (NTRS)

    Thompson, W. S.; Ruedger, W. H.

    1973-01-01

    A review of user requirements and updated instrumentation plans are presented for the aircraft tracking and guidance facility at NASA Wallops Station. User demand has increased as a result of new flight research programs; however, basic requirements remain the same as originally reported. Instrumentation plans remain essentially the same but with plans for up- and down-link telemetry more firm. With slippages in the laser acquisition schedule, added importance is placed on the FPS-16 radar as the primary tracking device until the laser is available. Limited simulation studies of a particular Kalman-type filter are also presented. These studies simulated the use of the filter in a helicopter guidance loop in a real-time mode. Disadvantages and limitations of this mode of operation are pointed out. Laser eyesafety calculations show that laser tracking of aircraft is readily feasible from the eyesafety viewpoint.

  19. Rethinking global health research: towards integrative expertise

    PubMed Central

    MacLachlan, Malcolm

    2009-01-01

    The Bamako Call for Action on Research for Health stresses the importance of inter-disciplinary, inter-ministerial and inter-sectoral working. This challenges much of our current research and postgraduate research training in health, which mostly seeks to produce narrowly focused content specialists. We now need to compliment this type of research and research training, by offering alternative pathways that seek to create expertise, not only in specific narrow content areas, but also in the process and context of research, as well as in the interaction of these different facets of knowledge. Such an approach, developing 'integrative expertise', could greatly facilitate better research utilisation, helping policy makers and practitioners work through more evidence-based practice and across traditional research boundaries. PMID:19643021

  20. Intelligent Integrated System Health Management

    NASA Technical Reports Server (NTRS)

    Figueroa, Fernando

    2012-01-01

    Intelligent Integrated System Health Management (ISHM) is the management of data, information, and knowledge (DIaK) with the purposeful objective of determining the health of a system (Management: storage, distribution, sharing, maintenance, processing, reasoning, and presentation). Presentation discusses: (1) ISHM Capability Development. (1a) ISHM Knowledge Model. (1b) Standards for ISHM Implementation. (1c) ISHM Domain Models (ISHM-DM's). (1d) Intelligent Sensors and Components. (2) ISHM in Systems Design, Engineering, and Integration. (3) Intelligent Control for ISHM-Enabled Systems

  1. Human System Integration: Regulatory Analysis

    NASA Technical Reports Server (NTRS)

    2005-01-01

    This document was intended as an input to the Access 5 Policy Integrated Product team. Using a Human System Integration (HIS) perspective, a regulatory analyses of the FARS (specifically Part 91), the Airman s Information Manual (AIM) and the FAA Controllers Handbook (7110.65) was conducted as part of a front-end approach needed to derive HSI requirements for Unmanned Aircraft Systems (UAS) operations in the National Airspace System above FL430. The review of the above aviation reference materials yielded eighty-four functions determined to be necessary or highly desirable for flight within the Air Traffic Management System. They include categories for Flight, Communications, Navigation, Surveillance, and Hazard Avoidance.

  2. Long-term monitoring and evaluation of a new system of community-based psychiatric care. Integrating research, teaching and practice at the University of Verona.

    PubMed

    Amaddeo, Francesco; Burti, Lorenzo; Ruggeri, Mirella; Tansella, Michele

    2009-01-01

    The South-Verona community psychiatric service (CPS) was implemented in 1978, according to Law 180, by the Department of Psychiatry of the University of Verona. Since then this CPS provides prompt, comprehensive and coherent answers to patients' needs, psychological and social, as well as practical, while trying to decrease and control symptoms. Special emphasis is given to integrating different interventions, such as medication, rehabilitation, family support, and social work. The South-Verona experience was from the beginning associated with a long-term research project of monitoring and evaluating the new system of care. The research team has grown and expanded over the years and presently includes the following research units: a) environmental, clinical and genetic determinants of the outcome of mental disorders; b) psychiatric register, economics and geography of mental health; c) clinical psychopharmacology and drug epidemiology; d) brain imaging and neuropsychology; e) clinical psychology and communication in medicine; and f) physical comorbidity and health promotion in psychiatric patients. This paper summarises the main results of the coordinated, long-term evaluative studies conducted so far. PMID:19567978

  3. Cottrell Scholars Collaborative -- Integrating Research and Teaching

    NASA Astrophysics Data System (ADS)

    Sinova, Jairo

    2013-03-01

    Higher education reform needs to move towards a more interactive and integrated model, in which there is greater curricular emphasis in skill development, multi-discipline integration, and innovative connectivity, rather than traditional content driven curricula. This is even more crucial in STEM education, given our current slow down relative to other countries and the need to remain competitive in a global environment. Successful reforms require a seamless integration of research and teaching where education excellence and research excellence are not viewed by faculty as a zero sum game but as mutually benefitting ingredients of academic success. Cottrell scholars are selected among top ranking young academics with an equal passionate commitment to research excellence and education. Recently, these national group of academics sponsored by the Research Corporation for Science Advancement have created the Cottrell Scholars Collaborative (CSC) which aims at creating a self-supporting group that promotes integration of research and teaching at a national level with different initiatives. I will describe in these talk the aim of this group and the different sponsored projects that CSC is undertaking and the types of collective and individual efforts that are making a difference in sustainable education reform.

  4. Integrated Research and Capacity Building in Geophysics

    NASA Astrophysics Data System (ADS)

    Willemann, R. J.; Lerner-Lam, A.; Nyblade, A.

    2008-05-01

    monitoring agencies, strategic international university partnerships, commitments to open data, and installation of permanent analysis systems that include open- source software. Such projects are intrinsically more complex than pure research - partly because they require funding from multiple sources to address diverse goals - but experience in Africa suggests that integrated programs contribute to long-term capacity building in ways that projects founded on basic research questions may not.

  5. Integrated agricultural energy system

    NASA Astrophysics Data System (ADS)

    Taylor, R. M.

    1985-08-01

    The purpose of this program is to show New England farmers and other New England energy users how they can use alternative energy sources to reduce their energy cost and dependency on conventional sources. The project demonstrates alternative energy technologies in solar, alcohol and methane. Dissemination is planned through tours to be conducted by the Worcester County Extension Service. Most of these goals were completed as planned. A few things have yet to be completed. The solar panels and solar hot water tanks have to be installed. The fermenter's agitating and cooling system have to be secured inside the fermenter. Once these items are complete tours will begin early in the spring.

  6. Integrated Building Management System (IBMS)

    SciTech Connect

    Anita Lewis

    2012-07-01

    This project provides a combination of software and services that more easily and cost-effectively help to achieve optimized building performance and energy efficiency. Featuring an open-platform, cloud- hosted application suite and an intuitive user experience, this solution simplifies a traditionally very complex process by collecting data from disparate building systems and creating a single, integrated view of building and system performance. The Fault Detection and Diagnostics algorithms developed within the IBMS have been designed and tested as an integrated component of the control algorithms running the equipment being monitored. The algorithms identify the normal control behaviors of the equipment without interfering with the equipment control sequences. The algorithms also work without interfering with any cooperative control sequences operating between different pieces of equipment or building systems. In this manner the FDD algorithms create an integrated building management system.

  7. Integrated high power VCSEL systems

    NASA Astrophysics Data System (ADS)

    Moench, Holger; Conrads, Ralf; Gronenborn, Stephan; Gu, Xi; Miller, Michael; Pekarski, Pavel; Pollmann-Retsch, Jens; Pruijmboom, Armand; Weichmann, Ulrich

    2016-03-01

    High power VCSEL systems are a novel laser source used for thermal treatment in industrial manufacturing. These systems will be applied in many applications, which have not used a laser source before. This is enabled by the unique combination of efficiency, compactness and robustness. High power VCSEL system technology encompasses elements far beyond the VCSEL chip itself: i.e. heat sinks, bonding technology and integrated optics. This paper discusses the optimization of these components and processes specifically for building high-power laser systems with VCSEL arrays. New approaches help to eliminate components and process steps and make the system more robust and easier to manufacture. New cooler concepts with integrated electrical and mechanical interfaces have been investigated and offer advantages for high power system design. The bonding process of chips on sub-mounts and coolers has been studied extensively and for a variety of solder materials. High quality of the interfaces as well as good reliability under normal operation and thermal cycling have been realized. A viable alternative to soldering is silver sintering. The very positive results which have been achieved with a variety of technologies indicate the robustness of the VCSEL chips and their suitability for high power systems. Beam shaping micro-optics can be integrated on the VCSEL chip in a wafer scale process by replication of lenses in a polymer layer. The performance of VCSEL arrays with integrated collimation lenses has been positively evaluated and the integrated chips are fully compatible with all further assembly steps. The integrated high power systems make the application even easier and more robust. New examples in laser material processing and pumping of solid state lasers are presented.

  8. Symplectic integrators for spin systems.

    PubMed

    McLachlan, Robert I; Modin, Klas; Verdier, Olivier

    2014-06-01

    We present a symplectic integrator, based on the implicit midpoint method, for classical spin systems where each spin is a unit vector in R{3}. Unlike splitting methods, it is defined for all Hamiltonians and is O(3)-equivariant, i.e., coordinate-independent. It is a rare example of a generating function for symplectic maps of a noncanonical phase space. It yields a new integrable discretization of the spinning top. PMID:25019718

  9. Integrated Photonics Research: Post-deadline papers

    NASA Astrophysics Data System (ADS)

    Quinn, Jarus W.

    1993-03-01

    The symposium was held on the following topics: advanced solid state lasers, compact blue-green lasers, integrated photonics research, nonlinear guide-wave optics, optical amplifiers and their applications, optical design for photonics, photonics in switching, quantum optoelectronics, short-wavelength -- physics with intense-laser pulses, soft x-ray protection lithography, ultrafast electronics and optoelectronics, optical computing, and spatial light modulators.

  10. Extracting Data From Integrated Student Information Systems.

    ERIC Educational Resources Information Center

    Yost, Michael

    An integrated student information system (ISIS) at Trinity University (Texas) is described with attention to how data are entered and how data are extracted for purposes of institutional research. The structure of the original ISIS files, the extract files, and the Statistical Package for the Social Sciences (SPSS) files is examined. An outline is…

  11. An integrated system for managing multidisciplinary oceanographic data collected in the Mediterranean Sea during the basin-scale research project EU/MAST-MATER (1996 2000)

    NASA Astrophysics Data System (ADS)

    Maillard, C.; Balopoulos, E.; Giorgetti, A.; Fichaut, M.; Iona, A.; Larour, M.; Latrouite, A.; Manca, B.; Maudire, G.; Nicolas, P.; Sanchez-Cabeza, J.-A.

    2002-06-01

    An advanced computer and communication technology was used to develop an integrated system and software tools for managing a great diversity of oceanographic data collected in the Mediterranean Sea during 1996-2000. Data were obtained during 108 sea cruises, carried out within the framework of the large-scale international research project MATER (mass transfer and ecosystem response), which was financially supported by the Marine Science and Technology (MAST) Programme of the European Union (EU). Data collection involved the active participation of various research vessels and personnel coming from 58 different laboratories of 13 countries. Data formatting as well as automatic and visual data quality controls were implemented using internationally accepted standards and procedures. Various data inventories and meta-data information, accessible through the World Wide Web (WWW), are made available to the user community. A database was developed, which, along with meta-data and other data relevant to the project information, is made available to the user community in the form of a CD-ROM. The database consists of 5861 vertical profiles and 842 time series of basic physical and biogeochemical parameters collected in the seawater column as well as biogeochemical parameters from the analysis of 70 sediment cores. Furthermore, it includes 67 cruise data files of nonstandard additional biological and atmospheric parameters.

  12. Leading with integrity: a qualitative research study.

    PubMed

    Storr, Loma

    2004-01-01

    This research paper gives an account of a study into the relationship between leadership and integrity. There is a critical analysis of the current literature for effective, successful and ethical leadership particularly, integrity. The purpose and aim of this paper is to build on the current notions of leadership within the literature, debate contemporary approaches, focussing specifically on practices within the UK National Health Service in the early 21st century. This leads to a discussion of the literature on ethical leadership theory, which includes public service values, ethical relationships and leading with integrity. A small study was undertaken consisting of 18 interviews with leaders and managers within a District General HospitaL Using the Repertory Grid technique and analysis 15 themes emerged from the constructs elicited, which were compared to the literature for leadership and integrity and other studies. As well as finding areas of overlap, a number of additional constructs were elicited which suggested that effective leadership correlates with integrity and the presence of integrity will improve organisational effectiveness. The study identified that perceptions of leadership character and behaviour are used to judge the effectiveness and integrity of a leader. However, the ethical implications and consequences of leaders' scope of power and influence such as policy and strategy are somewhat neglected and lacking in debate. The findings suggest that leaders are not judged according to the ethical nature of decision making, and leading and managing complex change but that the importance of integrity and ethical leadership correlated with higher levels of hierarchical status and that it is assumed by virtue of status and success that leaders lead with integrity. Finally, the findings of this study seem to suggest that nurse leadership capability is developing as a consequence of recent national investment. PMID:15588012

  13. Integrating Meteorology into Research on Migration

    PubMed Central

    Shamoun-Baranes, Judy; Bouten, Willem; van Loon, E. Emiel

    2010-01-01

    Atmospheric dynamics strongly influence the migration of flying organisms. They affect, among others, the onset, duration and cost of migration, migratory routes, stop-over decisions, and flight speeds en-route. Animals move through a heterogeneous environment and have to react to atmospheric dynamics at different spatial and temporal scales. Integrating meteorology into research on migration is not only challenging but it is also important, especially when trying to understand the variability of the various aspects of migratory behavior observed in nature. In this article, we give an overview of some different modeling approaches and we show how these have been incorporated into migration research. We provide a more detailed description of the development and application of two dynamic, individual-based models, one for waders and one for soaring migrants, as examples of how and why to integrate meteorology into research on migration. We use these models to help understand underlying mechanisms of individual response to atmospheric conditions en-route and to explain emergent patterns. This type of models can be used to study the impact of variability in atmospheric dynamics on migration along a migratory trajectory, between seasons and between years. We conclude by providing some basic guidelines to help researchers towards finding the right modeling approach and the meteorological data needed to integrate meteorology into their own research. PMID:20811515

  14. Human Research Program Integrated Research Plan. Revision A January 2009

    NASA Technical Reports Server (NTRS)

    2009-01-01

    The Integrated Research Plan (IRP) describes the portfolio of Human Research Program (HRP) research and technology tasks. The IRP is the HRP strategic and tactical plan for research necessary to meet HRP requirements. The need to produce an IRP is established in HRP-47052, Human Research Program - Program Plan, and is under configuration management control of the Human Research Program Control Board (HRPCB). Crew health and performance is critical to successful human exploration beyond low Earth orbit. The Human Research Program (HRP) is essential to enabling extended periods of space exploration because it provides knowledge and tools to mitigate risks to human health and performance. Risks include physiological and behavioral effects from radiation and hypogravity environments, as well as unique challenges in medical support, human factors, and behavioral or psychological factors. The Human Research Program (HRP) delivers human health and performance countermeasures, knowledge, technologies and tools to enable safe, reliable, and productive human space exploration. Without HRP results, NASA will face unknown and unacceptable risks for mission success and post-mission crew health. This Integrated Research Plan (IRP) describes HRP s approach and research activities that are intended to address the needs of human space exploration and serve HRP customers and how they are integrated to provide a risk mitigation tool. The scope of the IRP is limited to the activities that can be conducted with the resources available to the HRP; it does not contain activities that would be performed if additional resources were available. The timescale of human space exploration is envisioned to take many decades. The IRP illustrates the program s research plan through the timescale of early lunar missions of extended duration.

  15. The Systems Librarian: Re-Integrating the "Integrated" Library System

    ERIC Educational Resources Information Center

    Breeding, Marshall

    2005-01-01

    This article discusses the current environment of the ILS (Integrated Library System) plus add-ons tailored for electronic content and its future. It suggests that while the ILS may be mature, the supplemental products are not and the linkages among them are even less so. On the technical front, the recent interest in Web services gives reason to…

  16. STOVL aircraft simulation for integrated flight and propulsion control research

    NASA Technical Reports Server (NTRS)

    Mihaloew, James R.; Drummond, Colin K.

    1989-01-01

    The United States is in the initial stages of committing to a national program to develop a supersonic short takeoff and vertical landing (STOVL) aircraft. The goal of the propulsion community in this effort is to have the enabling propulsion technologies for this type aircraft in place to permit a low risk decision regarding the initiation of a research STOVL supersonic attack/fighter aircraft in the late mid-90's. This technology will effectively integrate, enhance, and extend the supersonic cruise, STOVL and fighter/attack programs to enable U.S. industry to develop a revolutionary supersonic short takeoff and vertical landing fighter/attack aircraft in the post-ATF period. A joint NASA Lewis and NASA Ames research program, with the objective of developing and validating technology for integrated-flight propulsion control design methodologies for short takeoff and vertical landing (STOVL) aircraft, was planned and is underway. This program, the NASA Supersonic STOVL Integrated Flight-Propulsion Controls Program, is a major element of the overall NASA-Lewis Supersonic STOVL Propulsion Technology Program. It uses an integrated approach to develop an integrated program to achieve integrated flight-propulsion control technology. Essential elements of the integrated controls research program are realtime simulations of the integrated aircraft and propulsion systems which will be used in integrated control concept development and evaluations. This paper describes pertinent parts of the research program leading up to the related realtime simulation development and remarks on the simulation structure to accommodate propulsion system hardware drop-in for real system evaluation.

  17. Two integrable systems with integrals of motion of degree four

    NASA Astrophysics Data System (ADS)

    Tsiganov, A. V.

    2016-03-01

    We discuss the possibility of using second-order Killing tensors to construct Liouville-integrable Hamiltonian systems that are not Nijenhuis integrable. As an example, we consider two Killing tensors with a nonzero Haantjes torsion that satisfy weaker geometric conditions and also three-dimensional systems corresponding to them that are integrable in Euclidean space and have two quadratic integrals of motion and one fourth-order integral in momenta.

  18. Integrative Role Of Cinematography In Biomechanics Research

    NASA Astrophysics Data System (ADS)

    Zernicke, Ronald F.; Gregor, Robert J.

    1982-02-01

    Cinematography is an integral element in the interdisciplinary biomechanics research conducted in the Department of Kinesiology at the University of California, Los Angeles. For either an isolated recording of a movement phenomenon or as a recording component which is synchronized with additional transducers and recording equipment, high speed motion picture film has been effectively incorporated into resr'arch projects ranging from two and three dimensional analyses of human movements, locomotor mechanics of cursorial mammals and primates, to the structural responses and dynamic geometries of skeletal muscles, tendons, and ligaments. The basic equipment used in these studies includes three, 16 mm high speed, pin-registered cameras which have the capacity for electronic phase-locking. Crystal oscillators provide the generator pulses to synchronize the timing lights of the cameras and the analog-to-digital recording equipment. A rear-projection system with a sonic digitizer permits quantification of film coordinates which are stored on computer disks. The capacity for synchronizing the high speed films with additional recording equipment provides an effective means of obtaining not only position-time data from film, but also electromyographic, force platform, tendon force transducer, and strain gauge recordings from tissues or moving organisms. During the past few years, biomechanics research which comprised human studies has used both planar and three-dimensional cinematographic techniques. The studies included planar analyses which range from the gait characteristics of lower extremity child amputees to the running kinematics and kinetics of highly skilled sprinters and long-distance runners. The dynamics of race cycling and kinetics of gymnastic maneuvers were studied with cinematography and either a multi-dimensional force platform or a bicycle pedal with strain gauges to determine the time histories of the applied forces. The three-dimensional technique

  19. Intelligent Control Systems Research

    NASA Technical Reports Server (NTRS)

    Loparo, Kenneth A.

    1994-01-01

    Results of a three phase research program into intelligent control systems are presented. The first phase looked at implementing the lowest or direct level of a hierarchical control scheme using a reinforcement learning approach assuming no a priori information about the system under control. The second phase involved the design of an adaptive/optimizing level of the hierarchy and its interaction with the direct control level. The third and final phase of the research was aimed at combining the results of the previous phases with some a priori information about the controlled system.

  20. RESEARCH INTEGRITY IN CHINA: PROBLEMS AND PROSPECTS

    PubMed Central

    RESNIK, DAVID; ZENG, WEIQIN

    2009-01-01

    In little more than 30 years, China has recovered from the intellectual stagnation brought about by the Cultural Revolution to become a global leader in science and technology. Like other leading countries in science and technology, China has encountered some ethical problems related to the conduct of research. China’s leaders have taken some steps to respond to these problems, such as developing ethics policies and establishing oversight committees. To keep moving forward, China needs to continue to take effective action to promote research integrity. Some of the challenges China faces include additional policy development, promoting education in responsible conduct of research, protecting whistle-blowers, and cultivating an ethical research environment. PMID:19832885

  1. Flight testing an integrated synthetic vision system

    NASA Astrophysics Data System (ADS)

    Kramer, Lynda J.; Arthur, Jarvis J., III; Bailey, Randall E.; Prinzel, Lawrence J., III

    2005-05-01

    NASA's Synthetic Vision Systems (SVS) project is developing technologies with practical applications to eliminate low visibility conditions as a causal factor to civil aircraft accidents while replicating the operational benefits of clear day flight operations, regardless of the actual outside visibility condition. A major thrust of the SVS project involves the development/demonstration of affordable, certifiable display configurations that provide intuitive out-the-window terrain and obstacle information with advanced pathway guidance for transport aircraft. The SVS concept being developed at NASA encompasses the integration of tactical and strategic Synthetic Vision Display Concepts (SVDC) with Runway Incursion Prevention System (RIPS) alerting and display concepts, real-time terrain database integrity monitoring equipment (DIME), and Enhanced Vision Systems (EVS) and/or improved Weather Radar for real-time object detection and database integrity monitoring. A flight test evaluation was jointly conducted (in July and August 2004) by NASA Langley Research Center and an industry partner team under NASA's Aviation Safety and Security, Synthetic Vision System project. A Gulfstream G-V aircraft was flown over a 3-week period in the Reno/Tahoe International Airport (NV) local area and an additional 3-week period in the Wallops Flight Facility (VA) local area to evaluate integrated Synthetic Vision System concepts. The enabling technologies (RIPS, EVS and DIME) were integrated into the larger SVS concept design. This paper presents experimental methods and the high level results of this flight test.

  2. Flight Testing an Integrated Synthetic Vision System

    NASA Technical Reports Server (NTRS)

    Kramer, Lynda J.; Arthur, Jarvis J., III; Bailey, Randall E.; Prinzel, Lawrence J., III

    2005-01-01

    NASA's Synthetic Vision Systems (SVS) project is developing technologies with practical applications to eliminate low visibility conditions as a causal factor to civil aircraft accidents while replicating the operational benefits of clear day flight operations, regardless of the actual outside visibility condition. A major thrust of the SVS project involves the development/demonstration of affordable, certifiable display configurations that provide intuitive out-the-window terrain and obstacle information with advanced pathway guidance for transport aircraft. The SVS concept being developed at NASA encompasses the integration of tactical and strategic Synthetic Vision Display Concepts (SVDC) with Runway Incursion Prevention System (RIPS) alerting and display concepts, real-time terrain database integrity monitoring equipment (DIME), and Enhanced Vision Systems (EVS) and/or improved Weather Radar for real-time object detection and database integrity monitoring. A flight test evaluation was jointly conducted (in July and August 2004) by NASA Langley Research Center and an industry partner team under NASA's Aviation Safety and Security, Synthetic Vision System project. A Gulfstream GV aircraft was flown over a 3-week period in the Reno/Tahoe International Airport (NV) local area and an additional 3-week period in the Wallops Flight Facility (VA) local area to evaluate integrated Synthetic Vision System concepts. The enabling technologies (RIPS, EVS and DIME) were integrated into the larger SVS concept design. This paper presents experimental methods and the high level results of this flight test.

  3. Assessing Global Water System Research

    NASA Astrophysics Data System (ADS)

    Braimoh, Ademola K.; Craswell, Eric T.

    2006-04-01

    Rapid growth of global change science has led to improved knowledge about interdependencies in the global water cycle and recognition that the global water system consists of physical, human, and biogeochemical components [Vörösmarty et al., 2004]. Traditionally, water research is spread over a number of scientific disciplines. However, for water science to effectively inform policy for sustainable water management, research about the dynamics of water in the context of global change needs to be holistic, must integrate the existing knowledge base, and should synthesize knowledge about how the interactions between nature and society at various scales are affecting the global water system. This article assesses the level of interdisciplinarity in water science programs by comparing the activities of international waterrelated projects with the Global Water System Project (GWSP) activity profile (http://www.gwsp.org). The GWSP is a project of the Earth System Science Partnership (ESSP) comprising the International Geosphere-Biosphere Programme (http:// www.igbp.kva.se/cgi-bin/php/frameset.php), the International Human Dimension Programme on Global Environmental Change (www.ihdp.org), the World Climate Research Programme (http://www.wmo.ch/web/wcrp/wcrp-home.html), and the DIVERSITAS international program on biodiversity science (http://www.diversitasinternational.org/). GWSP's attributes include its scientific and policy-informing orientation, global perspective, integrative and interdisciplinary approach, and multitemporal investigation of human impacts on water resources.

  4. Integrated Aeropropulsion Control System Design

    NASA Technical Reports Server (NTRS)

    Lin, C. -F.; Hurley, Francis X.; Huang, Jie; Hadaegh, F. Y.

    1996-01-01

    %T Integrated Aeropropulsion Control System Design%A C-F. Lin%A Francis X. Hurley%A Jie Huang%A F. Y. Hadaegh%J International Conference on Control and Information(psi)995%C Hong Kong%D June 1995%K aeropropulsion, control, system%U http://jpltrs.jpl.nasa.gov/1995/95-0658.pdfAn integrated intelligent control approach is proposed to design a high performance control system for aeropropulsion systems based on advanced sensor processing, nonlinear control and neural fuzzy control integration. Our approach features the following innovations:??e complexity and uncertainty issues are addressed via the distributed parallel processing, learning, and online reoptimization properties of neural networks.??e nonlinear dynamics and the severe coupling can be naturally incorporated into the design framework.??e knowledge base and decision making logic furnished by fuzzy systems leads to a human intelligence enhanced control scheme.In addition, fault tolerance, health monitoring and reconfigurable control strategies will be accommodated by this approach to ensure stability, graceful degradation and reoptimization in the case of failures, malfunctions and damage.!.

  5. Research Perspectives and Best Practices in Educational Technology Integration

    ERIC Educational Resources Information Center

    Keengwe, Jared

    2013-01-01

    With advancements in technology continuing to influence all areas of society, students in current classrooms have a different understanding and perspective of learning than the educational system has been designed to teach. Research Perspectives and Best Practices in Educational Technology Integration highlights the emerging digital age, its…

  6. Fiber optic control system integration

    NASA Technical Reports Server (NTRS)

    Poppel, G. L.; Glasheen, W. M.; Russell, J. C.

    1987-01-01

    A total fiber optic, integrated propulsion/flight control system concept for advanced fighter aircraft is presented. Fiber optic technology pertaining to this system is identified and evaluated for application readiness. A fiber optic sensor vendor survey was completed, and the results are reported. The advantages of centralized/direct architecture are reviewed, and the concept of the protocol branch is explained. Preliminary protocol branch selections are made based on the F-18/F404 application. Concepts for new optical tools are described. Development plans for the optical technology and the described system are included.

  7. Integrated image information management: research issues

    NASA Astrophysics Data System (ADS)

    Mehrotra, Rajiv; Pierson, William E., Jr.

    1995-06-01

    A vast number of applications including defense, medical, manufacturing, law enforcement, digital library, education, space exploration, weather forecasting, and entertainment require efficient management of huge collections of nonalphanumeric data. The most common and important nonalphanumeric data in most of these applications is image data. Owing to the availability of a variety of visual sensors, several large collections of images and related anciliary data exists and are rapidly growing. Examples of such collections include LANDSAT, weather, medical, and DoD target signature images. Unfortunately, in most cases only a fraction of the collected data is ever utilized to its full potential. The primary reason for this under-utilization is the lack of pictorial data management techniques/systems. Conventional data management systems are not designed to handle pictorial data in an integrated fashion, i.e., images and alphanumeric data are not treated equally. In such systems, an image is stored as a tag field in the description of some entity. Images are not entities and they cannot be key fields. Furthermore, content-based retrieval of images and related data is not possible. Therefore, new data management technologies need to be developed for an integrated management of textual and imagery data. This requires a clear understanding of the requirements and desireable characteristics of a pictorial data management system. In almost all image information management (or integrated image database) applications, image information modeling, content-based image information retrieval, and memeory management are the most important issues to be resolved. In this paper, the requirements of an integrated image information management system and the challenges posed by image data from the data modeling, the content-based retrieval, and the memory management viewpoints are discussed.

  8. Integrating legacy software toolkits into China-VO system

    NASA Astrophysics Data System (ADS)

    Wang, Xiao-Qian, Cui, Chen-Zhou, Zhao, Yong-Heng

    2005-12-01

    Virtual Observatory (VO) is a collection of data-archives and software toolkits. It aims to provide astronomers research resources with uniformed interfaces, using advanced information technologies. In this article, we discuss the necessaries and feasibilities of integrating legacy software toolkits into China-VO system at first; then analyse granularity about integrating. Three general integrating methods are given in detail. At last, we introduce an instance of integrating "Image Magick" - an software for image processing and discuss more about VO integration.

  9. Human Research Program Integrated Research Plan. Revision C

    NASA Technical Reports Server (NTRS)

    Steinberg, Susan

    2011-01-01

    Crew health and performance are critical to successful human exploration beyond low Earth orbit. The Human Research Program (HRP) is essential to enabling extended periods of space exploration because it provides knowledge and tools to mitigate risks to human health and performance. Risks include physiological effects from radiation and hypogravity environments, as well as unique challenges in medical support, human factors, and behavioral or psychological factors. The Human Research Program (HRP) delivers human health and performance countermeasures, knowledge, technologies and tools to enable safe, reliable, and productive human space exploration. Without HRP results, NASA will face unknown and unacceptable risks for mission success and post-mission crew health. This Integrated Research Plan (IRP) describes (1) HRP's approach and research activities that are intended to address the needs of human space exploration and serve HRP customers and (2) the method of integration for risk mitigation. The scope of the IRP is limited to the activities that can be conducted with the resources available to the HRP; it does not contain activities that would be performed if additional resources were available. The timescale of human space exploration is envisioned to take many decades. The IRP illustrates the program s research plan through the timescale of early lunar missions of extended duration.

  10. Integrating Stakeholders and Users into the Geography Discipline's Research Process

    USGS Publications Warehouse

    Hermans, Caroline M.; Taketa, Richard

    2006-01-01

    Future research priorities of Geography emphasize the discipline's leadership role in the U.S. Geological Survey (USGS) in multidisciplinary and integrated research on human and environmental systems and how these systems are interrelated and respond to change Geography's research priorities also emphasize providing science that is usable to society and creating decision support products applicable to given customer problems. To achieve these goals, we must understand the relationship between our research and our customer, and how to integrate the customer into the research process. This report details the elements of the research process that help achieve the degree of stakeholder involvement necessary to ensure a successful end-product. It offers suggestions that can help researchers better understand stakeholders and customers and involve them in the research process more effectively, while preserving the integrity of the science. Its aim is to help researchers understand the problems and challenges faced by our customers and communicate the ways in which Geography can help address their problems. Adopting these guidelines can improve the efficiency of the research process and lead to higher quality output. We will be able to conduct better research because we will have an improved understanding of the research problem and the stakeholders involved. This report covers a broad range of topics, from identifying and communicating with stakeholders and users, to the use of language, to how to effectively present scientific information to the user. It does not offer a 'one size fits all' method. Instead, perhaps only specific sections are suitable for a given project and customers, depending on project scope and needs. This report is based on the objectives of Geography's strategic plan, U. S. Geological Survey's strategic plan, and Department of Interior's strategic plan. Section 2 of these guidelines describes the purpose of the research process in Geography and