Science.gov

Sample records for intense longitudinal retreatment

  1. Intensive training induces longitudinal changes in meditation state-related EEG oscillatory activity

    PubMed Central

    Saggar, Manish; King, Brandon G.; Zanesco, Anthony P.; MacLean, Katherine A.; Aichele, Stephen R.; Jacobs, Tonya L.; Bridwell, David A.; Shaver, Phillip R.; Rosenberg, Erika L.; Sahdra, Baljinder K.; Ferrer, Emilio; Tang, Akaysha C.; Mangun, George R.; Wallace, B. Alan; Miikkulainen, Risto; Saron, Clifford D.

    2012-01-01

    The capacity to focus one's attention for an extended period of time can be increased through training in contemplative practices. However, the cognitive processes engaged during meditation that support trait changes in cognition are not well characterized. We conducted a longitudinal wait-list controlled study of intensive meditation training. Retreat participants practiced focused attention (FA) meditation techniques for three months during an initial retreat. Wait-list participants later undertook formally identical training during a second retreat. Dense-array scalp-recorded electroencephalogram (EEG) data were collected during 6 min of mindfulness of breathing meditation at three assessment points during each retreat. Second-order blind source separation, along with a novel semi-automatic artifact removal tool (SMART), was used for data preprocessing. We observed replicable reductions in meditative state-related beta-band power bilaterally over anteriocentral and posterior scalp regions. In addition, individual alpha frequency (IAF) decreased across both retreats and in direct relation to the amount of meditative practice. These findings provide evidence for replicable longitudinal changes in brain oscillatory activity during meditation and increase our understanding of the cortical processes engaged during meditation that may support long-term improvements in cognition. PMID:22973218

  2. Longitudinal asymmetries of the coronal line intensities

    NASA Astrophysics Data System (ADS)

    Xanthakis, J.; Petropoulos, B.; Tritakis, V. P.; Mavromichalaki, H.; Marmatsuri, L.

    The analysis of the daily measurements of the coronal green line intensity which have been collected by the Pic-du-Midi Observatory during the period 1944-1974 has led to some very interesting results. The main finding of this analysis is a permanent longitudinal asymmetry of the green line intensity which has been determined all along the data record. In an effort to make this asymmetry certain E-W intensity differences very close to the solar equator where the rotation rate for coronal features is equal to 25.35 days on the average are examined. When these data are examined every 25 days, namely data which almost correspond to the same points of the solar disk, it confirms the above mentioned longitudinal asymmetry.

  3. Transverse-longitudinal coupling in intense beams

    SciTech Connect

    Wang, T.S.F.; Smith, L.

    1981-03-01

    The coupling between transverse and longitudinal perturbations is studied self-consistently by considering a beam of K-V distribution. The analysis is carried out within the context of linearized Vlasov-Maxwell equations and electrostatic approximation. The perturbation is assumed to be azimuthally symmetric but axially non-uniform (k/sub z/ is not equal to 0). It is shown that the coupling affects both the longitudinal and transverse modes significantly in the high density and low frequency region. Two new classes of longitudinal modes are found which would not exist if the transverse motions of particles are neglected. The effect of resistive wall impedance on beam stability is also studied. It is found that the longitudinal impedance can cause the transverse modes also to be weakly unstable.

  4. Retreat, Hell!

    ERIC Educational Resources Information Center

    Sims, Wil

    1978-01-01

    Describes an annual fall retreat for junior college newspaper staffs, which involves a program of workshops and discussions about problems, goals, and staff members' roles; offers advice on planning such a retreat. (GW)

  5. Exploring Intensive Longitudinal Measures of Student Engagement in Blended Learning

    ERIC Educational Resources Information Center

    Henrie, Curtis R.; Bodily, Robert; Manwaring, Kristine C.; Graham, Charles R.

    2015-01-01

    In this exploratory study we used an intensive longitudinal approach to measure student engagement in a blended educational technology course, collecting both self-report and observational data. The self-report measure included a simple survey of Likert-scale and open-ended questions given repeatedly during the semester. Observational data were…

  6. The radial and longitudinal dependence of SEP intensities and fluences

    NASA Astrophysics Data System (ADS)

    Li, G.; Zank, G.; Verkhoglyadova, O.; Ruzmaikin, A.; Feynman, J.; Jun, I.

    Solar Energetic Particles SEPs are an important hazard in the context of space weather These particles bombard spacecraft and can cause instruments onboard to malfunction At sufficiently high energies and dosages they can also be extremely harmful to biological materials human bodies and are therefore one of the major safety concerns for the future manned spacecraft program We now know that these particles are associated with Coronal Mass Ejection CMEs driven shocks As a CME-driven shock propagates outward particles are injected and accelerated at the shock front via a first order Fermi mechanism aka diffusive shock acceleration After being accelerated the particles convect with the shock diffuse both upstream and downstream of the shock and many eventually escape the shock complex after reaching far upstream downstream In this work we present a model calculation of the SEP time intensity profile The model is based on a 2D-ZEUS MHD code which is used to simulate the solar wind The shock is modeled using a shell model where particle convection and diffusion are followed numerically When particles reach some distance ahead of the shock they are can escape from the shock Their subsequent motion is followed using a Monte-Carlo approach This sophisticated model allows us to obtain a time intensity profile and instantaneous particle spectra at various locations We will discuss the radial and longitudinal dependence of both the intensities and fluences

  7. Analytical Solutions for the Nonlinear Longitudinal Drift Compression (Expansion) of Intense Charged Particle Beams

    SciTech Connect

    Edward A. Startsev; Ronald C. Davidson

    2004-04-09

    To achieve high focal spot intensities in heavy ion fusion, the ion beam must be compressed longitudinally by factors of ten to one hundred before it is focused onto the target. The longitudinal compression is achieved by imposing an initial velocity profile tilt on the drifting beam. In this paper, the problem of longitudinal drift compression of intense charged particle beams is solved analytically for the two important cases corresponding to a cold beam, and a pressure-dominated beam, using a one-dimensional warm-fluid model describing the longitudinal beam dynamics.

  8. Longitudinal confinement and matching of an intense electron beam

    NASA Astrophysics Data System (ADS)

    Beaudoin, B.; Haber, I.; Kishek, R. A.; Bernal, S.; Koeth, T.; Sutter, D.; O'Shea, P. G.; Reiser, M.

    2011-01-01

    An induction cell has successfully been demonstrated to longitudinally confine a space-charge dominated bunch for over a thousand turns (>11.52 km) in the University of Maryland Electron Ring [Haber et al., Nucl. Instrum. Methods Phys. Res. A 606, 64 (2009) and R. A. Kishek et al., Int. J. Mod. Phys. A 22, 3838 (2007)]. With the use of synchronized periodic focusing fields, the beam is confined for multiple turns overcoming the longitudinal space-charge forces. Experimental results show that an optimum longitudinal match is obtained when the focusing frequency for containment of the 0.52 mA beam is applied at every fifth turn. Containment of the beam bunch is achievable at lower focusing frequencies, at the cost of a reduction in the transported charge from the lack of sufficient focusing. Containment is also obtainable, if the confinement fields overfocus the bunch, exciting multiple waves at the bunch ends, which propagate into the central region of the beam, distorting the overall constant current beam shape.

  9. Mean-field thalamocortical modeling of longitudinal EEG acquired during intensive meditation training.

    PubMed

    Saggar, Manish; Zanesco, Anthony P; King, Brandon G; Bridwell, David A; MacLean, Katherine A; Aichele, Stephen R; Jacobs, Tonya L; Wallace, B Alan; Saron, Clifford D; Miikkulainen, Risto

    2015-07-01

    Meditation training has been shown to enhance attention and improve emotion regulation. However, the brain processes associated with such training are poorly understood and a computational modeling framework is lacking. Modeling approaches that can realistically simulate neurophysiological data while conforming to basic anatomical and physiological constraints can provide a unique opportunity to generate concrete and testable hypotheses about the mechanisms supporting complex cognitive tasks such as meditation. Here we applied the mean-field computational modeling approach using the scalp-recorded electroencephalogram (EEG) collected at three assessment points from meditating participants during two separate 3-month-long shamatha meditation retreats. We modeled cortical, corticothalamic, and intrathalamic interactions to generate a simulation of EEG signals recorded across the scalp. We also present two novel extensions to the mean-field approach that allow for: (a) non-parametric analysis of changes in model parameter values across all channels and assessments; and (b) examination of variation in modeled thalamic reticular nucleus (TRN) connectivity over the retreat period. After successfully fitting whole-brain EEG data across three assessment points within each retreat, two model parameters were found to replicably change across both meditation retreats. First, after training, we observed an increased temporal delay between modeled cortical and thalamic cells. This increase provides a putative neural mechanism for a previously observed reduction in individual alpha frequency in these same participants. Second, we found decreased inhibitory connection strength between the TRN and secondary relay nuclei (SRN) of the modeled thalamus after training. This reduction in inhibitory strength was found to be associated with increased dynamical stability of the model. Altogether, this paper presents the first computational approach, taking core aspects of physiology and

  10. Longitudinal Density Modulation and Energy Conversion in Intense Beams

    SciTech Connect

    Harris, J; Neumann, J; Tian, K; O'Shea, P

    2006-02-17

    Density modulation of charged particle beams may occur as a consequence of deliberate action, or may occur inadvertently because of imperfections in the particle source or acceleration method. In the case of intense beams, where space charge and external focusing govern the beam dynamics, density modulation may under some circumstances be converted to velocity modulation, with a corresponding conversion of potential energy to kinetic energy. Whether this will occur depends on the properties of the beam and the initial modulation. This paper describes the evolution of discrete and continuous density modulations on intense beams, and discusses three recent experiments related to the dynamics of density-modulated electron beams.

  11. The promise of intensive longitudinal data capture for behavioral health research.

    PubMed

    Ginexi, Elizabeth M; Riley, William; Atienza, Audie A; Mabry, Patricia L

    2014-05-01

    Advances in technology and the associated cultural norms, especially the advent of the smartphone, offer an unprecedented opportunity to collect data on relevant health behaviors and experiences unobtrusively at a greater frequency and in greater volumes than ever before. This special issue will acquaint the readership of Nicotine and Tobacco Research with the potential for intensive longitudinal data and will illustrate some innovative analytic techniques for addressing research questions associated with this type of complex data. This introductory article will provide a brief history of the analytic techniques for intensive longitudinal data and will point to some resources that support and enable the use of these techniques. PMID:24711629

  12. The Promise of Intensive Longitudinal Data Capture for Behavioral Health Research

    PubMed Central

    2014-01-01

    Advances in technology and the associated cultural norms, especially the advent of the smartphone, offer an unprecedented opportunity to collect data on relevant health behaviors and experiences unobtrusively at a greater frequency and in greater volumes than ever before. This special issue will acquaint the readership of Nicotine and Tobacco Research with the potential for intensive longitudinal data and will illustrate some innovative analytic techniques for addressing research questions associated with this type of complex data. This introductory article will provide a brief history of the analytic techniques for intensive longitudinal data and will point to some resources that support and enable the use of these techniques. PMID:24711629

  13. Breaking of relativistically intense longitudinal space charge waves: A description using Dawson sheet model

    NASA Astrophysics Data System (ADS)

    Sengupta, Sudip

    2014-02-01

    Spatio-temporal evolution of relativistically intense longitudinal space charge waves in a cold homogeneous plasma is studied analytically as well as numerically, as an initial value problem, using Dawson sheet model. It is found that, except for very special initial conditions which generates the well known longitudinal Akhiezer-Polovin mode, for all other initial conditions, the waves break through a novel mechanism called phase mixing at an amplitude well below the Akhiezer-Polovin limit. An immediate consequence of this is, that Akhiezer-Polovin waves break when subjected to arbitrarily small longitudinal perturbations. We demonstrate this by performing extensive numerical simulations. This result may be of direct relevance to ultrashort, ultraintense laser/beam pulse-plasma interaction experiments where relativistically intense waves are routinely excited.

  14. Breaking of relativistically intense longitudinal space charge waves: A description using Dawson sheet model

    SciTech Connect

    Sengupta, Sudip

    2014-02-11

    Spatio-temporal evolution of relativistically intense longitudinal space charge waves in a cold homogeneous plasma is studied analytically as well as numerically, as an initial value problem, using Dawson sheet model. It is found that, except for very special initial conditions which generates the well known longitudinal Akhiezer-Polovin mode, for all other initial conditions, the waves break through a novel mechanism called phase mixing at an amplitude well below the Akhiezer-Polovin limit. An immediate consequence of this is, that Akhiezer-Polovin waves break when subjected to arbitrarily small longitudinal perturbations. We demonstrate this by performing extensive numerical simulations. This result may be of direct relevance to ultrashort, ultraintense laser/beam pulse-plasma interaction experiments where relativistically intense waves are routinely excited.

  15. Poisson Growth Mixture Modeling of Intensive Longitudinal Data: An Application to Smoking Cessation Behavior

    ERIC Educational Resources Information Center

    Shiyko, Mariya P.; Li, Yuelin; Rindskopf, David

    2012-01-01

    Intensive longitudinal data (ILD) have become increasingly common in the social and behavioral sciences; count variables, such as the number of daily smoked cigarettes, are frequently used outcomes in many ILD studies. We demonstrate a generalized extension of growth mixture modeling (GMM) to Poisson-distributed ILD for identifying qualitatively…

  16. Long path-length experimental studies of longitudinal phenomena in intense beams

    NASA Astrophysics Data System (ADS)

    Beaudoin, B. L.; Haber, I.; Kishek, R. A.; Bernal, S.; Koeth, T. W.

    2016-05-01

    Intense charged particle beams are nonneutral plasmas as they can support a host of plasma waves and instabilities. The longitudinal physics, for a long beam, can often be reasonably described by a 1-D cold-fluid model with a geometry factor to account for the transverse effects. The plasma physics of such beams has been extensively studied theoretically and computationally for decades, but until recently, the only experimental measurements were carried out on relatively short linacs. This work reviews experimental studies over the past five years on the University of Maryland Electron Ring, investigating longitudinal phenomena over time scales of thousands of plasma periods, illustrating good agreement with simulations.

  17. Long-path-length experimental studies of longitudinal phenomena in intense beams

    NASA Astrophysics Data System (ADS)

    Beaudoin, Brian

    2015-11-01

    Intense charged particle beams are nonneutral plasmas and they can support a host of plasma waves and instabilities. For a long beam bunch, the longitudinal physics can often be reasonably described by a 1-D cold-fluid model, with a geometry factor to account for the transverse effects. The plasma physics of such beams has been extensively studied theoretically and computationally for decades, but until recently, the only experimental measurements were carried out on relatively short linacs. This work reviews experimental studies over the past 5 years on the U. Maryland Electron Ring, investigating longitudinal phenomena, for the first time, over time scales of hundreds and thousands of plasma periods. These results are in good agreement with theory and simulation. Topics that will be discussed are: Longitudinal confinement of a long bunch using barrier fields. The generation of space charge waves from barrier field mismatches, their propagation along the bunch and reflection at the beam ends, as well as their long-term dissipation. The characterization of solitary waves from density/velocity perturbations in the center of the bunch. Compression of solitary wave trains with velocity ``tilts'' (head-to-tail gradient). Observation of a multi-stream instability driven by the longitudinal merging of bunches and the characterization of the onset of the instability with a PIC code. The shock-wave compression of a bunch using rapidly-moving barrier fields.

  18. Participation in an Intensive Longitudinal Study with Weekly Web Surveys Over 2.5 Years

    PubMed Central

    Barber, Jennifer; Kusunoki, Yasamin; Schulz, Paul

    2016-01-01

    Background Technological advances have made it easier for researchers to collect more frequent longitudinal data from survey respondents via personal computers, smartphones, and other mobile devices. Although technology has led to an increase in data-intensive longitudinal studies, little is known about attrition from such studies or the differences between respondents who complete frequently administered surveys in a timely manner, and respondents who do not. Objective We examined respondent characteristics and behaviors associated with continued and on-time participation in a population-based intensive longitudinal study, using weekly web-based survey interviews over an extended period. Methods We analyzed data from the Relationship Dynamics and Social Life study, an intensive longitudinal study that collected weekly web-based survey interviews for 2.5 years from 1003 18- and 19-year-olds to investigate factors shaping the dynamics of their sexual behavior, contraceptive use, and pregnancies. Results Ordinary least squares and logistic regression analyses showed background respondent characteristics measured at baseline were associated with the number of days respondents remained enrolled in the study, the number of interviews they completed, and the odds that they were late completing interviews. In addition, we found that changes in pregnancy-related behaviors reported in the weekly interviews were associated with late completion of interviews. Specifically, after controlling for sociodemographic, personality, contact information, and prior experience variables, we found that weekly reports such as starting to have sex (odds ratio [OR] 1.17, 95% CI 1.03-1.32, P=.01), getting a new partner (OR 1.76, 95% CI 1.53-2.03, P<.001), stopping the use of contraception (OR 1.28, 95% CI 1.10-1.49, P=.001), and having a new pregnancy (OR 5.57, 95% CI 4.26-7.29, P<.001) were significantly associated with late survey completion. However, young women who reported changes in

  19. Relating multi-sequence longitudinal intensity profiles and clinical covariates in incident multiple sclerosis lesions

    PubMed Central

    Sweeney, Elizabeth M.; Shinohara, Russell T.; Dewey, Blake E.; Schindler, Matthew K.; Muschelli, John; Reich, Daniel S.; Crainiceanu, Ciprian M.; Eloyan, Ani

    2015-01-01

    The formation of multiple sclerosis (MS) lesions is a complex process involving inflammation, tissue damage, and tissue repair — all of which are visible on structural magnetic resonance imaging (MRI) and potentially modifiable by pharmacological therapy. In this paper, we introduce two statistical models for relating voxel-level, longitudinal, multi-sequence structural MRI intensities within MS lesions to clinical information and therapeutic interventions: (1) a principal component analysis (PCA) and regression model and (2) function-on-scalar regression models. To do so, we first characterize the post-lesion incidence repair process on longitudinal, multi-sequence structural MRI from 34 MS patients as voxel-level intensity profiles. For the PCA regression model, we perform PCA on the intensity profiles to develop a voxel-level biomarker for identifying slow and persistent, long-term intensity changes within lesion tissue voxels. The proposed biomarker's ability to identify such effects is validated by two experienced clinicians (a neuroradiologist and a neurologist). On a scale of 1 to 4, with 4 being the highest quality, the neuroradiologist gave the score on the first PC a median quality rating of 4 (95% CI: [4,4]), and the neurologist gave the score a median rating of 3 (95% CI: [3,3]). We then relate the biomarker to the clinical information in a mixed model framework. Treatment with disease-modifying therapies (p < 0.01), steroids (p < 0.01), and being closer to the boundary of abnormal signal intensity (p < 0.01) are all associated with return of a voxel to an intensity value closer to that of normal-appearing tissue. The function-on-scalar regression model allows for assessment of the post-incidence time points at which the covariates are associated with the profiles. In the function-on-scalar regression, both age and distance to the boundary were found to have a statistically significant association with the lesion intensities at some time point

  20. The importance of physical activity and sleep for affect on stressful days: Two intensive longitudinal studies.

    PubMed

    Flueckiger, Lavinia; Lieb, Roselind; Meyer, Andrea H; Witthauer, Cornelia; Mata, Jutta

    2016-06-01

    We investigated the potential stress-buffering effect of 3 health behaviors-physical activity, sleep quality, and snacking-on affect in the context of everyday life in young adults. In 2 intensive longitudinal studies with up to 65 assessment days over an entire academic year, students (Study 1, N = 292; Study 2, N = 304) reported stress intensity, sleep quality, physical activity, snacking, and positive and negative affect. Data were analyzed using multilevel regression analyses. Stress and positive affect were negatively associated; stress and negative affect were positively associated. The more physically active than usual a person was on a given day, the weaker the association between stress and positive affect (Study 1) and negative affect (Studies 1 and 2). The better than usual a person's sleep quality had been during the previous night, the weaker the association between stress and positive affect (Studies 1 and 2) and negative affect (Study 2). The association between daily stress and positive or negative affect did not differ as a function of daily snacking (Studies 1 and 2). On stressful days, increasing physical activity or ensuring high sleep quality may buffer adverse effects of stress on affect in young adults. These findings suggest potential targets for health-promotion and stress-prevention programs, which could help reduce the negative impact of stress in young adults. (PsycINFO Database Record PMID:26709860

  1. What's in a Day? A Guide to Decomposing the Variance in Intensive Longitudinal Data

    PubMed Central

    de Haan-Rietdijk, Silvia; Kuppens, Peter; Hamaker, Ellen L.

    2016-01-01

    In recent years there has been a growing interest in the use of intensive longitudinal research designs to study within-person processes. Examples are studies that use experience sampling data and autoregressive modeling to investigate emotion dynamics and between-person differences therein. Such designs often involve multiple measurements per day and multiple days per person, and it is not clear how this nesting of the data should be accounted for: That is, should such data be considered as two-level data (which is common practice at this point), with occasions nested in persons, or as three-level data with beeps nested in days which are nested in persons. We show that a significance test of the day-level variance in an empty three-level model is not reliable when there is autocorrelation. Furthermore, we show that misspecifying the number of levels can lead to spurious or misleading findings, such as inflated variance or autoregression estimates. Throughout the paper we present instructions and R code for the implementation of the proposed models, which includes a novel three-level AR(1) model that estimates moment-to-moment inertia and day-to-day inertia. Based on our simulations we recommend model selection using autoregressive multilevel models in combination with the AIC. We illustrate this method using empirical emotion data from two independent samples, and discuss the implications and the relevance of the existence of a day level for the field. PMID:27378986

  2. The Application of Intensive Longitudinal Methods to Investigate Change: Stimulating the Field of Applied Family Research.

    PubMed

    Bamberger, Katharine T

    2016-03-01

    The use of intensive longitudinal methods (ILM)-rapid in situ assessment at micro timescales-can be overlaid on RCTs and other study designs in applied family research. Particularly, when done as part of a multiple timescale design-in bursts over macro timescales-ILM can advance the study of the mechanisms and effects of family interventions and processes of family change. ILM confers measurement benefits in accurately assessing momentary and variable experiences and captures fine-grained dynamic pictures of time-ordered processes. Thus, ILM allows opportunities to investigate new research questions about intervention effects on within-subject (i.e., within-person, within-family) variability (i.e., dynamic constructs) and about the time-ordered change process that interventions induce in families and family members beginning with the first intervention session. This paper discusses the need and rationale for applying ILM to family intervention evaluation, new research questions that can be addressed with ILM, example research using ILM in the related fields of basic family research and the evaluation of individual-based interventions. Finally, the paper touches on practical challenges and considerations associated with ILM and points readers to resources for the application of ILM. PMID:26541560

  3. LONGITUDINAL AND RADIAL DEPENDENCE OF SOLAR ENERGETIC PARTICLE PEAK INTENSITIES: STEREO, ACE, SOHO, GOES, AND MESSENGER OBSERVATIONS

    SciTech Connect

    Lario, D.; Ho, G. C.; Decker, R. B.; Roelof, E. C.; Aran, A.; Gomez-Herrero, R.; Dresing, N.; Heber, B.

    2013-04-10

    Simultaneous measurements of solar energetic particle (SEP) events by two or more of the spacecraft located near 1 AU during the rising phase of solar cycle 24 (i.e., STEREO-A, STEREO-B, and near-Earth spacecraft such as ACE, SOHO, and GOES) are used to determine the longitudinal dependence of 71-112 keV electron, 0.7-3 MeV electron, 15-40 MeV proton, and 25-53 MeV proton peak intensities measured in the prompt component of SEP events. Distributions of the peak intensities for the selected 35 events with identifiable solar origin are approximated by the form exp [ - ({phi} - {phi}{sub 0}){sup 2}/2{sigma}{sup 2}], where {phi} is the longitudinal separation between the parent active region and the footpoint of the nominal interplanetary magnetic field (IMF) line connecting each spacecraft with the Sun, {phi}{sub 0} is the distribution centroid, and {sigma} determines the longitudinal gradient. The MESSENGER spacecraft, at helioradii R < 1 AU, allows us to determine a lower limit to the radial dependence of the 71-112 keV electron peak intensities measured along IMF lines. We find five events for which the nominal magnetic footpoint of MESSENGER was less than 20 Degree-Sign apart from the nominal footpoint of a spacecraft near 1 AU. Although the expected theoretical radial dependence for the peak intensity of the events observed along the same field line can be approximated by a functional form R {sup -{alpha}} with {alpha} < 3, we find two events for which {alpha} > 3. These two cases correspond to SEP events occurring in a complex interplanetary medium that favored the enhancement of peak intensities near Mercury but hindered the SEP transport to 1 AU.

  4. Tips for a Successful Leadership Retreat

    ERIC Educational Resources Information Center

    Bonstingl, John Jay

    2005-01-01

    This article focuses on planning a retreat for board, leadership team, or community and business partners. The author provides 10 suggestions for effective retreat planning: (1) Plan one's retreat with a clear purpose in mind; (2) Make retreat more relevant; (3) Build on current and past successes; (4) Make sure the right people are invited and…

  5. Intensity based methods for brain MRI longitudinal registration. A study on multiple sclerosis patients.

    PubMed

    Diez, Yago; Oliver, Arnau; Cabezas, Mariano; Valverde, Sergi; Martí, Robert; Vilanova, Joan Carles; Ramió-Torrentà, Lluís; Rovira, Alex; Lladó, Xavier

    2014-07-01

    Registration is a key step in many automatic brain Magnetic Resonance Imaging (MRI) applications. In this work we focus on longitudinal registration of brain MRI for Multiple Sclerosis (MS) patients. First of all, we analyze the effect that MS lesions have on registration by synthetically eliminating some of the lesions. Our results show how a widely used method for longitudinal registration such as rigid registration is practically unconcerned by the presence of MS lesions while several non-rigid registration methods produce outputs that are significantly different. We then focus on assessing which is the best registration method for longitudinal MRI images of MS patients. In order to analyze the results obtained for all studied criteria, we use both descriptive statistics and statistical inference: one way ANOVA, pairwise t-tests and permutation tests. PMID:24338728

  6. Longitudinal and transverse deformation of human Achilles tendon induced by isometric plantar flexion at different intensities.

    PubMed

    Iwanuma, Soichiro; Akagi, Ryota; Kurihara, Toshiyuki; Ikegawa, Shigeki; Kanehisa, Hiroaki; Fukunaga, Tetsuo; Kawakami, Yasuo

    2011-06-01

    The present study determined in vivo deformation of the entire Achilles tendon in the longitudinal and transverse directions during isometric plantar flexions. Twelve young women and men performed isometric plantar flexions at 0% (rest), 30%, and 60% of the maximal voluntary contraction (MVC) while a series of oblique longitudinal and cross-sectional magnetic resonance (MR) images of the Achilles tendon were taken. At the distal end of the soleus muscle belly, the Achilles tendon was divided into the aponeurotic (ATapo) and the tendinous (ATten) components. The length of each component was measured in the MR images. The widths of the Achilles tendon were determined at 10 regions along ATapo and at four regions along ATten. Longitudinal and transverse strains were calculated as changes in relative length and width compared with those at rest. The ATapo deformed in both longitudinal and transverse directions at 30%MVC and 60%MVC. There was no difference between the strains of the ATapo at 30%MVC and 60%MVC either in the longitudinal (1.1 and 1.6%) or transverse (5.0∼11.4 and 5.0∼13.9%) direction. The ATten was elongated longitudinally (3.3%) to a greater amount than ATapo, while narrowing transversely in the most distal region (-4.6%). The current results show that the magnitude and the direction of contraction-induced deformation of Achilles tendon are different for the proximal and distal components. This may be related to the different functions of Achilles tendon, i.e., force transmission or elastic energy storage during muscle contractions. PMID:21415176

  7. Why Intensive Interventions Matter: Longitudinal Studies of Adolescents with Reading Disabilities and Poor Reading Comprehension

    ERIC Educational Resources Information Center

    Solis, Michael; Miciak, Jeremy; Vaughn, Sharon; Fletcher, Jack M.

    2014-01-01

    We describe findings from a series of longitudinal studies utilizing a response to intervention framework implemented over 3 years with students in Grades 6 through 8 with reading disabilities and poor reading comprehension. Students were identified based on reading comprehension scores in Grade 5 (n = 1,083) and then randomized to treatment or…

  8. A Longitudinal Examination of Breadth and Intensity of Youth Activity Involvement and Successful Development

    ERIC Educational Resources Information Center

    Busseri, Michael A.; Rose-Krasnor, Linda; Willoughby, Teena; Chalmers, Heather

    2006-01-01

    Connections between youth activity involvement and indicators of successful development were examined in a longitudinal high school sample. Drawing on theories of expertise skill development (e.g., J. Cote, 1999); the selection, optimization, and compensation framework (P. B. Baltes, 1997); and theories of positive youth development (e.g., R. M.…

  9. Intensity of Participation in Organized Youth Activities during the High School Years: Longitudinal Associations with Adjustment

    ERIC Educational Resources Information Center

    Denault, Anne-Sophie; Poulin, Francois; Pedersen, Sara

    2009-01-01

    The goal of this study was to explore the longitudinal associations between youth activity participation and adjustment over the high school years by examining (a) correlations between participation and adjustment growth curves, and (b) bidirectional links between participation and adjustment from one year to the next. Participation was…

  10. USEPA PATHOGEN EQUIVALENCY COMMITTEE RETREAT

    EPA Science Inventory

    The Pathogen Equivalency Committee held its retreat from September 20-21, 2005 at Hueston Woods State Park in College Corner, Ohio. This presentation will update the PEC’s membership on emerging pathogens, analytical methods, disinfection techniques, risk analysis, preparat...

  11. Phase speed and frequency-dependent damping of longitudinal intensity oscillations in coronal loop structures observed with AIA/SDO

    NASA Astrophysics Data System (ADS)

    Abedini, A.

    2016-04-01

    Longitudinal intensity oscillations along coronal loops that are interpreted as signatures of magneto-acoustic waves are observed frequently in different coronal structures. The aim of this paper is to estimate the physical parameters of the slow waves and the quantitative dependence of these parameters on their frequencies in the solar corona loops that are situated above active regions with the Atmospheric Imaging Assembly (AIA) onboard Solar Dynamic Observatory (SDO). The observed data on 2012-Feb-12, consisting of 300 images with an interval of 24 seconds in the 171 Å and 193 Å passbands is analyzed for evidence of propagating features as slow waves along the loop structures. Signatures of longitudinal intensity oscillations that are damped rapidly as they travel along the loop structures were found, with periods in the range of a few minutes to few tens of minutes. Also, the projected (apparent) phase speeds, projected damping lengths, damping times and damping qualities of filtered intensities centred on the dominant frequencies are measured in the range of Cs ≃38-79 km s^{-1}, Ld≃ 23-68 Mm, τd≃7-21 min and τ_{d/P}≃0.34-0.77, respectively. The theoretical and observational results of this study indicate that the damping times and damping lengths increase with increasing the oscillation periods, and are highly sensitive function of oscillation period, but the projected speeds and the damping qualities are not very sensitive to the oscillation periods. Furthermore, the magnitude values of physical parameters are in good agreement with the prediction of the theoretical dispersion relations of high-frequency MHD waves (>1.1 mHz) in a coronal plasma with electron number density in the range of ne≃107-10^{12} cm^{-3}.

  12. Why Intensive Interventions Matter: Longitudinal Studies of Adolescents With Reading Disabilities and Poor Reading Comprehension

    PubMed Central

    Solis, Michael; Miciak, Jeremy; Vaughn, Sharon; Fletcher, Jack M.

    2014-01-01

    We describe findings from a series of longitudinal studies utilizing a response to intervention framework implemented over 3 years with students in Grades 6 through 8 with reading disabilities and poor reading comprehension. Students were identified based on reading comprehension scores in Grade 5 (n = 1,083) and then randomized to treatment or comparison conditions. Beginning in sixth grade, students assigned to intervention were provided treatment for 1, 2, or 3 years based on their response to instruction in each preceding year. Screening procedures, progress monitoring tools, tiers of instruction, and findings from each year of the study are reported. Additional studies investigating reading and behavioral outcomes through multi-level, growth modeling, and studies of the cognitive and neural correlates of inadequate response are also reported. PMID:25378799

  13. A Longitudinal Study of Breadth and Intensity of Activity Involvement and the Transition to University

    ERIC Educational Resources Information Center

    Busseri, Michael A.; Rose-Krasnor, Linda; Pancer, S. Mark; Pratt, Michael W.; Adams, Gerald R.; Birnie-Lefcovitch, Shelly; Polivy, Janet; Wintre, Maxine Gallander

    2011-01-01

    We examined prospective relations between activity involvement and successful transitioning to university. A sample of 656 students from 6 Canadian universities completed questionnaires before beginning university and at the end of their first year. Breadth (number of different activity domains) and intensity (mean frequency) of activity…

  14. Influence of supplemental vitamin D on intensity of benign paroxysmal positional vertigo: A longitudinal clinical study

    PubMed Central

    Sheikhzadeh, Mahboobeh; Lotfi, Yones; Mousavi, Abdollah; Heidari, Behzad; Monadi, Mohsen; Bakhshi, Enayatollah

    2016-01-01

    Background: Benign paroxysmal positional vertigo (BPPV) is linked to vitamin D deficiency. This clinical trial aimed to determine the influence of vitamin D supplementation on intensity of BPPV. Methods: The study population was selected consecutively and the diagnosis of BPPV was made by history and clinical examination and exclusion of other conditions. Intensity of BPVV was assessed based on VAS score (0-10). Serum 25-hydroxyvitamin D (25-OHD) was measured using ELISA method and levels < 20 ng/ml was considered a deficiency. All patients received rehabilitation treatment using Epley's maneuver one time per week for one month. Serum 25-OHD deficient patients were classified as treated and non-treated groups (rehabilitation with or without 50.000 IU cholecalciferol weekly for two months).The results of treatment were compared with vitamin D sufficient group as control. All patients were followed-up for 6 months. Results: After two months of treatment, in both vitamin D treated and non-treated groups the intensity of BPPV decreased significantly as compared with control (P=0.001 for both groups) but at endpoint, the intensity of BPPV aggravated and regressed to the baseline value in vitamin D deficient non-treated group (P=0.001) whereas, in vitamin D treated group, improvement of BPPV remained stable and unchanged over the study period. Conclusion: This study indicates that correction of vitamin D deficiency in BPPV provides additional benefit to rehabilitation therapy (Epley maneuver) regarding duration of improvement. These findings suggest serum 25-OHD measurement in recurrent BPPV. PMID:27386060

  15. Smooth transverse and longitudinal focusing in high-intensity ion linacs

    SciTech Connect

    Billen, J.H.; Takeda, Harunori; Young, L.M.

    1996-09-01

    We examine ion linac designs that start with a high energy radio- frequency quadrupole (RFQ) followed by either a drift-tube linac (DTL) or a coupled-cavity drift-tube linac (CCDTL). For high energies a conventional CCL follows the CCDTL. High RFQ output energy allows tailoring the transverse and longitudinal focusing strengths to match into the following structure. When the RFQ beam enters a higher frequency structure, the DTL or CCDTL starts with a low accelerating gradient and large negative synchronous phase. The gradient and phase both ramp up gradually to higher values. Other changes later in the machine are also gradual. Beam dynamics simulations show that these linacs require no separate matching sections. Applications include a cw 100 mA H{sup +} beam from a 350-MHz, 6.7 MeV RFQ injecting a 700 MHz CCDTL and CCL; a 7% duty 28 mA H{sup -} beam from a 402.5 MHz RFQ and DTL injecting 805 MHz structures; a cw 135 mA D{sup +} beam produced by a 175 MHz, 8 MeV RFQ and DTL; and a 2.4% duty, 80 mA H{sup +} beam using a 433 MHz 10 MeV RFQ and a 1300 MHz CCDTL. The machines take advantage of the considerable flexibility of the CCDTL. Designs can use a variety of different transverse focusing lattices. Use of two coupling cavity orientations permits a constant period even when the number of drift tubes per cavity changes along the linac.

  16. A Distributed Network for Intensive Longitudinal Monitoring in Metastatic Triple-Negative Breast Cancer

    PubMed Central

    Blau, C. Anthony; Ramirez, Arturo B.; Blau, Sibel; Pritchard, Colin C.; Dorschner, Michael O.; Schmechel, Stephen C.; Martins, Timothy J.; Mahen, Elisabeth M.; Burton, Kimberly A.; Komashko, Vitalina M.; Radenbaugh, Amie J.; Dougherty, Katy; Thomas, Anju; Miller, Christopher P.; Annis, James; Fromm, Jonathan R.; Song, Chaozhong; Chang, Elizabeth; Howard, Kellie; Austin, Sharon; Schmidt, Rodney A.; Linenberger, Michael L.; Becker, Pamela S.; Senecal, Francis M.; Mecham, Brigham H.; Lee, Su-In; Madan, Anup; Ronen, Roy; Dutkowski, Janusz; Heimfeld, Shelly; Wood, Brent L.; Stilwell, Jackie L.; Kaldjian, Eric P.; Haussler, David; Zhu, Jingchun

    2016-01-01

    Accelerating cancer research is expected to require new types of clinical trials. This report describes the Intensive Trial of OMics in Cancer (ITOMIC) and a participant with triple-negative breast cancer metastatic to bone, who had markedly elevated circulating tumor cells (CTCs) that were monitored 48 times over 9 months. A total of 32 researchers from 14 institutions were engaged in the patient’s evaluation; 20 researchers had no prior involvement in patient care and 18 were recruited specifically for this patient. Whole-exome sequencing of 3 bone marrow samples demonstrated a novel ROS1 variant that was estimated to be present in most or all tumor cells. After an initial response to cisplatin, a hypothesis of crizotinib sensitivity was disproven. Leukapheresis followed by partial CTC enrichment allowed for the development of a differential high-throughput drug screen and demonstrated sensitivity to investigational BH3-mimetic inhibitors of BCL-2 that could not be tested in the patient because requests to the pharmaceutical sponsors were denied. The number and size of CTC clusters correlated with clinical status and eventually death. Focusing the expertise of a distributed network of investigators on an intensively monitored patient with cancer can generate high-resolution views of the natural history of cancer and suggest new opportunities for therapy. Optimization requires access to investigational drugs. PMID:26733551

  17. A Distributed Network for Intensive Longitudinal Monitoring in Metastatic Triple-Negative Breast Cancer.

    PubMed

    Blau, C Anthony; Ramirez, Arturo B; Blau, Sibel; Pritchard, Colin C; Dorschner, Michael O; Schmechel, Stephen C; Martins, Timothy J; Mahen, Elisabeth M; Burton, Kimberly A; Komashko, Vitalina M; Radenbaugh, Amie J; Dougherty, Katy; Thomas, Anju; Miller, Christopher P; Annis, James; Fromm, Jonathan R; Song, Chaozhong; Chang, Elizabeth; Howard, Kellie; Austin, Sharon; Schmidt, Rodney A; Linenberger, Michael L; Becker, Pamela S; Senecal, Francis M; Mecham, Brigham H; Lee, Su-In; Madan, Anup; Ronen, Roy; Dutkowski, Janusz; Heimfeld, Shelly; Wood, Brent L; Stilwell, Jackie L; Kaldjian, Eric P; Haussler, David; Zhu, Jingchun

    2016-01-01

    Accelerating cancer research is expected to require new types of clinical trials. This report describes the Intensive Trial of OMics in Cancer (ITOMIC) and a participant with triple-negative breast cancer metastatic to bone, who had markedly elevated circulating tumor cells (CTCs) that were monitored 48 times over 9 months. A total of 32 researchers from 14 institutions were engaged in the patient's evaluation; 20 researchers had no prior involvement in patient care and 18 were recruited specifically for this patient. Whole-exome sequencing of 3 bone marrow samples demonstrated a novel ROS1 variant that was estimated to be present in most or all tumor cells. After an initial response to cisplatin, a hypothesis of crizotinib sensitivity was disproven. Leukapheresis followed by partial CTC enrichment allowed for the development of a differential high-throughput drug screen and demonstrated sensitivity to investigational BH3-mimetic inhibitors of BCL-2 that could not be tested in the patient because requests to the pharmaceutical sponsors were denied. The number and size of CTC clusters correlated with clinical status and eventually death. Focusing the expertise of a distributed network of investigators on an intensively monitored patient with cancer can generate high-resolution views of the natural history of cancer and suggest new opportunities for therapy. Optimization requires access to investigational drugs. PMID:26733551

  18. Multi-spacecraft observations of solar energetic particle events in the rising phase of solar cycle 24: Longitudinal and radial intensity gradients

    NASA Astrophysics Data System (ADS)

    Lario, D.; Roelof, E. C.; Ho, G. C.

    2012-04-01

    The current fleet of spacecraft spread throughout the inner heliosphere (i.e., STEREO-A, STEREO-B, ACE, SOHO, and MESSENGER) allows us to estimate the longitudinal and radial gradients in intensity of solar energetic particle (SEP) events during the rise of solar cycle 24. Simultaneous measurements of individual SEP events by two or more of the first four of the above spacecraft (all near 1 AU) allow us to infer the longitudinal gradient of SEP peak intensities. Distributions of the peak intensities for the events with identifiable solar origin are approximated by the form exp[-k(φ-φ0)2], where φ is the longitudinal separation between the parent active region and the footpoint of the field line connecting each spacecraft with the Sun, φ0 is the distribution centroid and k determines the longitudinal gradient. Those events for which MESSENGER is nominally connected along the interplanetary magnetic field to one of the spacecraft near 1 AU allow us to infer a lower limit to the radial intensity gradient along magnetic field lines. During the decay phase of the events, periods of similar intensities are commonly observed by spacecraft well separated in longitude and, when connection to MESSENGER permits, by spacecraft along the same nominal interplanetary field line. Those periods of null intensity gradients are known as energetic particle reservoirs. Observations of radial and longitudinal intensity gradients as well as energetic particle reservoirs made by Helios during solar cycle 21 [Lario et al., ApJ, 653, 1531-1544, 2006] provide an important point of comparison.

  19. Tunable High-Intensity Electron Bunch Train Production Based on Nonlinear Longitudinal Space Charge Oscillation.

    PubMed

    Zhang, Zhen; Yan, Lixin; Du, Yingchao; Zhou, Zheng; Su, Xiaolu; Zheng, Lianmin; Wang, Dong; Tian, Qili; Wang, Wei; Shi, Jiaru; Chen, Huaibi; Huang, Wenhui; Gai, Wei; Tang, Chuanxiang

    2016-05-01

    High-intensity trains of electron bunches with tunable picosecond spacing are produced and measured experimentally with the goal of generating terahertz (THz) radiation. By imposing an initial density modulation on a relativistic electron beam and controlling the charge density over the beam propagation, density spikes of several-hundred-ampere peak current in the temporal profile, which are several times higher than the initial amplitudes, have been observed for the first time. We also demonstrate that the periodic spacing of the bunch train can be varied continuously either by tuning launching phase of a radio-frequency gun or by tuning the compression of a downstream magnetic chicane. Narrow-band coherent THz radiation from the bunch train was also measured with μJ-level energies and tunable central frequency of the spectrum in the range of ∼0.5 to 1.6 THz. Our results pave the way towards generating mJ-level narrow-band coherent THz radiation and driving high-gradient wakefield-based acceleration. PMID:27203327

  20. Tunable High-Intensity Electron Bunch Train Production Based on Nonlinear Longitudinal Space Charge Oscillation

    NASA Astrophysics Data System (ADS)

    Zhang, Zhen; Yan, Lixin; Du, Yingchao; Zhou, Zheng; Su, Xiaolu; Zheng, Lianmin; Wang, Dong; Tian, Qili; Wang, Wei; Shi, Jiaru; Chen, Huaibi; Huang, Wenhui; Gai, Wei; Tang, Chuanxiang

    2016-05-01

    High-intensity trains of electron bunches with tunable picosecond spacing are produced and measured experimentally with the goal of generating terahertz (THz) radiation. By imposing an initial density modulation on a relativistic electron beam and controlling the charge density over the beam propagation, density spikes of several-hundred-ampere peak current in the temporal profile, which are several times higher than the initial amplitudes, have been observed for the first time. We also demonstrate that the periodic spacing of the bunch train can be varied continuously either by tuning launching phase of a radio-frequency gun or by tuning the compression of a downstream magnetic chicane. Narrow-band coherent THz radiation from the bunch train was also measured with μ J -level energies and tunable central frequency of the spectrum in the range of ˜0.5 to 1.6 THz. Our results pave the way towards generating mJ-level narrow-band coherent THz radiation and driving high-gradient wakefield-based acceleration.

  1. A Longitudinal Study of the TEACCH Program in Different Settings: The Potential Benefits of Low Intensity Intervention in Preschool Children with Autism Spectrum Disorder

    ERIC Educational Resources Information Center

    D'Elia, Lidia; Valeri, Giovanni; Sonnino, Fabiana; Fontana, Ilaria; Mammone, Alessia; Vicari, Stefano

    2014-01-01

    We conducted a longitudinal study of 30 preschool children with autism spectrum disorders (ASDs) to evaluate the potential benefits of the Treatment and Education of Autistic and related Communication Handicapped Children (TEACCH). Fifteen children following a low intensity TEACCH program were assessed four times for autism severity, adaptive…

  2. Columbia Glacier in 1986; 800 meters retreat

    USGS Publications Warehouse

    Krimmel, R.M.

    1987-01-01

    Columbia Glacier, in Prince William Sound, Alaska, continued its rapid retreat in 1986, with a retreat of 800 m. Average velocity of the lower portion of the glacier, 10 September 1986 to 26 January 1987, was three km/yr, or about one-half of the velocity during similar periods for the previous three years. This reduced velocity is a new development in the progression of the retreat, and if the calving rate follows the pattern of previous years, will result in continued retreat. (Author 's abstract)

  3. Longitudinal assessment of quality of life after surgery, conformal brachytherapy, and intensity-modulated radiation therapy for prostate cancer

    PubMed Central

    Zelefsky, Michael J.; Poon, Bing Ying; Eastham, James; Vickers, Andrew; Pei, Xin; Scardino, Peter T.

    2016-01-01

    Purpose We evaluated quality-of-life changes (QoL) in 907 patients treated with either radical prostatectomy (open or laparoscopic), real-time planned conformal brachytherapy, or high-dose intensity-modulated radiotherapy (IMRT) on a prospective IRB-approved longitudinal study. Methods Validated questionnaires given pretreatment (baseline) and at 3, 6, 9, 12, 15, 18, 24, 36, and 48 months addressed urinary function, urinary bother, bowel function, bowel bother, sexual function, and sexual bother. Results At 48 months, surgery had significantly higher urinary incontinence than others (both P<.001), but fewer urinary irritation/obstruction symptoms (all P<.001). Very low levels of bowel dysfunction were observed and only small subsets in each group showed rectal bleeding. Brachytherapy and IMRT showed better sexual function than surgery accounting for baseline function and other factors (delta 14.29 of 100, 95% CI, 8.57–20.01; and delta 10.5, 95% CI, 3.78–17.88). Sexual bother was similar. Four-year outcomes showed persistent urinary incontinence for surgery with more obstructive urinary symptoms for radiotherapy. Using modern radiotherapy delivery, bowel function deterioration is less-often observed. Sexual function was strongly affected in all groups yet significantly less for radiotherapy. Conclusions Treatment selection should include patient preferences and balance predicted disease-free survival over a projected time vs potential impairment of QoL important for the patient. PMID:26780999

  4. Endodontic retreatment. 1: Indications and case selection.

    PubMed

    Chong, B S; Pitt Ford, T R

    1996-10-01

    Conventional root canal treatment, despite having a reportedly high success rate may not invariably lead to the desired healing response in clinical practice because of shortcomings in the treatment. This is the first of two articles on this subject, and will cover indications and case selection for root canal retreatment. Part 2 will discuss methods of retreatment. PMID:9452622

  5. Retreating to Advance Women Geoscience Faculty

    NASA Astrophysics Data System (ADS)

    O'Connell, Suzanne; Holmes, Mary Anne

    2007-11-01

    Geoscience Academics in the Northeast (GAIN) Writing Retreat; Dover, Massachusetts, 29 July to 3 August 2007 Seventeen women geoscientists from New England, New York, and New Jersey assembled for a writing retreat at Boston College's Connors Family Retreat and Conference Center, set on 80 pastoral acres on the outskirts of Boston. Funded through the National Science Foundation ADVANCE program, the retreat had two objectives: to facilitate writing and to develop a supportive community. It succeeded on both accounts. Although new to science, retreats of this sort have long been a highly sought after experience for writers in other disciplines. The potential benefits for scientists, in particular, women scientists, are great. Writing is a cornerstone of our work, yet we struggle to find time for it, juggling the demands of students, teaching, family, domestic chores, and research.

  6. Glacial Retreat in Chilean Patagonia

    NASA Technical Reports Server (NTRS)

    2002-01-01

    The San Quintin Glacier is the largest outflow glacier of the Northern Patagonian Ice Field in southern Chile. Its terminus is a piedmont lobe just short of the Golfo de Penas on the Pacific Ocean and just north of 47oS. Like many glaciers worldwide during the twentieth century, San Quintin appears to be losing mass and possibly retreating. Such a change is evident in these two photographs taken by astronauts only seven years apart. The first was taken by the crew of STS-068 in October1994 and the second by the Increment 4 crew of the International Space Station in February 2002. Even with the reversal of season and different lighting conditions of these two acquisitions, a loss of mass and change of structure, particularly in the lobe, are strikingly evident in these comparative photos. Glaciers are one of the special topics identified as scientific objectives for monitoring with photography from the International Space Station. Astronaut photography is a complimentary source of remote sensing data available for use with other sensor systems being used to monitor and study glaciers (see an ASTER image of the San Quintin Glacier). They also provide strong, visual context information on glacier environments and processes using a familiar medium, the camera. Images STS068-260-73 and ISS004-E-7267 were provided by the Earth Sciences and Image Analysis Laboratory at Johnson Space Center. Additional images taken by astronauts and cosmonauts can be viewed at the NASA-JSC Gateway to Astronaut Photography of Earth.

  7. Endodontic retreatment: an online study guide.

    PubMed

    2008-05-01

    The Editorial Board of the Journal of Endodontics has developed a literature-based study guide of topical areas related to endodontics. This study guide is intended to give the reader a focused review of the essential endodontic literature and does not cite all possible articles related to each topic. Although citing all articles would be comprehensive, it would defeat the idea of a study guide. This section will cover retreatment rationale, corrosion of silver points, retreatment techniques, removal of posts, and possible complications during retreatment. PMID:18457690

  8. Ocean forcing drives glacier retreat sometimes

    NASA Astrophysics Data System (ADS)

    Bassis, J. N.; Ultee, E.; Ma, Y.

    2015-12-01

    Observations show that marine-terminating glaciers respond to climate forcing nonlinearly, with periods of slow or negligible glacier advance punctuated by abrupt, rapid retreat. Once glacier retreat has initiated, glaciers can quickly stabilize with a new terminus position. Alternatively, retreat can be sustained for decades (or longer), as is the case for Columbia Glacier, Alaska where retreat initiated ~1984 and continues to this day. Surprisingly, patterns of glacier retreat show ambiguous or even contradictory correlations with atmospheric temperature and glacier surface mass balance. Despite these puzzles, observations increasingly show that intrusion of warm subsurface ocean water into fjords can lead to glacier erosion rates that can account for a substantial portion of the total mass lost from glaciers. Here we use a simplified flowline model to show that even relatively modest submarine melt rates (~100 m/a) near the terminus of grounded glaciers can trigger large increases in iceberg calving leading to rapid glacier retreat. However, the strength of the coupling between submarine melt and calving is a strong function of the geometry of the glacier (bed topography, ice thickness and glacier width). This can lead to irreversible retreat when the terminus is thick and grounded deeply beneath sea level or result in little change when the glacier is relatively thin, grounded in shallow water or pinned in a narrow fjord. Because of the strong dependence on glacier geometry, small perturbations in submarine melting can trigger glaciers in their most advanced—and geometrically precarious—state to undergo sudden retreat followed by much slower re-advance. Although many details remain speculative, our model hints that some glaciers are more sensitive than others to ocean forcing and that some of the nonlinearities of glacier response to climate change may be attributable to variations in difficult-to-detect subsurface water temperatures that need to be better

  9. Four Retreats and a Forum: A Meditation on Retreats as a Response to Change.

    ERIC Educational Resources Information Center

    Dobb, Linda S.

    1999-01-01

    Describes four library retreats held by the Bowling Green State University library staff from 1995 to 1998. The retreats reflect changes in library work and management theory that have occurred. The importance of technology to library work is recognized, but there is also a growing realization of the importance of developing a flexible staff…

  10. Do Higher Sea-cliff Retreat Rates Imply Faster Sea-cliff Retreat?

    NASA Astrophysics Data System (ADS)

    Mushkin, A.; Katz, O.; Porat, N.

    2015-12-01

    Inland retreat of sea cliffs in response to post LGM (last glacial maximum) sea-level rise is an ongoing process that affects coastal environments and communities worldwide. Here, we examine a globally recurring pattern where reported sea-cliff retreat rates since the 20th century often appear to exceed longer-term millennial-scale ('background') rates that rarely exceed ~0.1 m/yr. Focusing on Israel's 30-km-long Mediterranean 'Sharon' sea-cliff as a case study we demonstrate that such apparent increase in rates may also reflect a widely acknowledged sampling bias in geologic rate estimates inferred from observation time windows ('Tobs') shorter than process episodicity. We show that this possible bias leads to an ambiguity in conventional rate estimates obtained by averaging observed retreat distances over Tobs, and that as a result despite ubiquitous and robust observations of cliff retreat since the 20th century (e.g., aerial photographs) recent/current retreat rates for many of the world's episodically retreating sea cliffs remain essentially unknown. To address this present limitation in our ability to detect and quantify recent changes in sea-cliff retreat rates we use airborne LiDAR to measure the continuous wave-driven volumetric erosion of collapsed material from the cliff base as an effective upper-bound constraint for the m/yr rate of episodic retreat of the cliff itself. We find that while conventional retreat rate estimates since the 20th century along the Sharon sea cliff artefactually increase up to several m/yr as an inverse function of Tobs, the LiDAR-constrained retreat rates are not susceptible to this sampling bias, are comparable to the cliff's background retreat rate of 0.03-0.07 m/yr since the mid Holocene and thus indicate no recent acceleration in retreat. This ability to unambiguously constrain sea-cliff retreat rates with annual to decadal-scale observations directly impacts the global-scale push to quantify, better understand and

  11. Summary of the RHIC Retreat 2007

    SciTech Connect

    Pilat,F.; Gardner, C.; Montag, C.; Roser, T.

    2008-08-01

    The RHIC Retreat 2007 took place on July 16-17 2007 at the Foxwoods Resort in CT, about 3 weeks after the end of the RHIC Run-7. The goal of the Retreat is traditionally to plan the upcoming run in the light of the results from the previous one, by providing a snapshot of the present understanding of the machine and a forum for free and frank discussion. A particular attention was paid to the challenge of increasing the time at store, and the related issue of system reliability. An interesting Session covered all new developments aimed to improve the machine performance and luminosity. In Section 2 we summarize the results from Run-7 for RHIC and the injectors and discuss the present objectives of the RHIC program and performance. Sections 3-6 are summaries of the Retreat sessions focused on preparation for deuteron gold and polarized protons, respectively, machine availability and new developments.

  12. Twelfth-Grade Student Work Intensity Linked to Later Educational Attainment and Substance Use: New Longitudinal Evidence

    ERIC Educational Resources Information Center

    Bachman, Jerald G.; Staff, Jeremy; O'Malley, Patrick M.; Schulenberg, John E.; Freedman-Doan, Peter

    2011-01-01

    Long hours of paid employment during high school have been linked to a variety of problem behaviors, but questions remain about whether and to what extent work intensity makes any causal contribution. This study addresses those questions by focusing on how 12th-grade work intensity is associated with substance use and educational attainment in the…

  13. Roof Shield for Advance and Retreat Mining

    NASA Technical Reports Server (NTRS)

    Lewis, E. V.

    1985-01-01

    Shield sections change their configuration to suit mining mode. Articulation cylinders raise rear shield to advance position, and locking cylinders hold it there. To change to retreat position articulation cylinders lower shield. Locking pins at edge of outermost shield plate latch shield to chock base. Shield accommodates roof heights ranging from 36 to 60 inches (0.9 to 1.52 meters).

  14. Comparing a narcissistic and an autistic retreat: 'looking through or at the window'.

    PubMed

    Strauss, L V

    2012-02-01

    In this paper I discuss two different forms of psychic retreats that I encountered in the treatment of a patient who suffered from two traumatic experiences: the loss of his mother when he was 2 years old and his 'near-death' experience when he was five. In the parasitic narcissistic retreat, using intensive projective identification enabled him to create an impasse in the form of a 'high tide - low tide' scenario in which alternating hope and disappointment kept the process going, yet paralyzed development. The autistic retreat, for its part, led to the collapse of projective identification mechanisms, dismantling and disrupting the transference/countertransference negotiations. The emerging state of non-communication and 'near death' seemed to act as a protection against the unbearable pain of abandonment and desolation. PMID:22320137

  15. The Board Retreat: For Listening, Learning and Understanding.

    ERIC Educational Resources Information Center

    Read, James W.

    Retreats, which have been used by churches and corporations for some time, are currently being looked into by college presidents and boards of trustees as a means of training and problem solving. While many types of retreats may not be appropriate for boards, a well-planned working retreat can be an effective way for trustees to: (1) really get to…

  16. A Longitudinal Investigation of the Effects of Computer Anxiety on Performance in a Computing-Intensive Environment

    ERIC Educational Resources Information Center

    Buche, Mari W.; Davis, Larry R.; Vician, Chelley

    2007-01-01

    Computers are pervasive in business and education, and it would be easy to assume that all individuals embrace technology. However, evidence shows that roughly 30 to 40 percent of individuals experience some level of computer anxiety. Many academic programs involve computing-intensive courses, but the actual effects of this exposure on computer…

  17. Microorganism penetration in dentinal tubules of instrumented and retreated root canal walls. In vitro SEM study

    PubMed Central

    Al-Sulaiman, Alaa; Al-Rasheed, Fellwa; Alnajjar, Fatimah; Al-Abdulwahab, Bander; Al-Badah, Abdulhakeem

    2014-01-01

    Objectives This in vitro study aimed to investigate the ability of Candida albicans (C. albicans) and Enterococcus faecalis (E. faecalis) to penetrate dentinal tubules of instrumented and retreated root canal surface of split human teeth. Materials and Methods Sixty intact extracted human single-rooted teeth were divided into 4 groups, negative control, positive control without canal instrumentation, instrumented, and retreated. Root canals in the instrumented group were enlarged with endodontic instruments, while root canals in the retreated group were enlarged, filled, and then removed the canal filling materials. The teeth were split longitudinally after canal preparation in 3 groups except the negative control group. The teeth were inoculated with both microorganisms separately and in combination. Teeth specimens were examined by scanning electron microscopy (SEM), and the depth of penetration into the dentinal tubules was assessed using the SMILE view software (JEOL Ltd). Results Penetration of C. albicans and E. faecalis into the dentinal tubules was observed in all 3 groups, although penetration was partially restricted by dentin debris of tubules in the instrumented group and remnants of canal filling materials in the retreated group. In all 3 groups, E. faecalis penetrated deeper into the dentinal tubules by way of cell division than C. albicans which built colonies and penetrated by means of hyphae. Conclusions Microorganisms can easily penetrate dentinal tubules of root canals with different appearance based on the microorganism size and status of dentinal tubules. PMID:25383343

  18. Moraine formation during an advance/retreat cycle at a temperate alpine glacier

    NASA Astrophysics Data System (ADS)

    Brook, M.; Quincey, D.; Winkler, S.

    2012-04-01

    Mountain glaciers are highly sensitive to variations in temperature and precipitation, and so moraine records from such systems are strong indicators of climate change. Due to the prevailing trend of retreat of the majority of mountain glaciers globally over the last few decades, there are limited opportunities to observe moraine formation, especially at temperate alpine glaciers. In the Southern Alps of New Zealand, while glaciers have all experienced a major retreat since the late 19th century, within this loss of ice mass, there has been a distinct variance in individual glacier response. Indeed, while Tasman Glacier, the longest glacier in the Southern Alps has thinned and entered into the current phase of calving retreat in the early 1990s, the steeper, more responsive glaciers to the west of the Main Divide, such as Franz Josef and Fox Glacier have experienced more elaborate advance/retreat phases. We focus on moraine formation at Fox Glacier, a c. 12.5 km long valley glacier terminating at 300 m above sea level. Fox Glacier retreated substantially since the 1930s, before advancing 800 m between the mid-1980s and 1999. A minor retreat then followed until 2005, succeeded by a 300 m re-advance until 2007-8. Continued retreat and down-wasting has since followed. Superimposed on this alternating advance/retreat cycle, have been minor winter re-advances. Sedimentological and morphological information were combined with detailed observations, historical photos and recent time-lapse photography of the terminus. Characteristics of several modes of moraine formation have been observed: (1) the late 20th century advance culminated in a broad <5 m high terminal moraine, formed by an admixture of "bulldozed" proglacial sediments and dumping of supraglacial material; (2) the 21st century short-lived advances were characterized by 1-2 m high (often multi-crested) ridges with a "saw-tooth" plan-form controlled by longitudinal crevasses outcropping at the terminus; (3) time

  19. Retreatments after multifocal intraocular lens implantation: an analysis

    PubMed Central

    Gundersen, Kjell Gunnar; Makari, Sarah; Ostenstad, Steffen; Potvin, Rick

    2016-01-01

    Purpose To determine the incidence and etiology of required retreatment after multifocal intraocular lens (IOL) implantation and to evaluate the methods and clinical outcomes of retreatment. Patients and methods A retrospective chart review of 416 eyes of 209 patients from one site that underwent uncomplicated cataract surgery with multifocal IOL implantation. Biometry, the IOL, and refractive data were recorded after the original implantation, with the same data recorded after retreatment. Comments related to vision were obtained both before and after retreatment for retreated patients. Results The multifocal retreatment rate was 10.8% (45/416 eyes). The eyes that required retreatment had significantly higher residual refractive astigmatism compared with those who did not require retreatment (1.21±0.51 D vs 0.51±0.39 D, P<0.01). The retreatment rate for the two most commonly implanted primary IOLs, blended bifocal (10.5%, 16/152) and bilateral trifocal (6.9%, 14/202) IOLs, was not statistically significantly different (P=0.12). In those requiring retreatment, refractive-related complaints were most common. Retreatment with refractive corneal surgery, in 11% of the eyes, and piggyback IOLs, in 89% of the eyes, was similarly successful, improving patient complaints 78% of the time. Conclusion Complaints related to ametropia were the main reasons for retreatment. Residual astigmatism appears to be an important determinant of retreatment rate after multifocal IOL implantation. Retreatment can improve symptoms for a high percentage of patients; a piggyback IOL is a viable retreatment option. PMID:27041983

  20. Improving Self-Guiding of an Ultra-Intense Laser by Tailoring the Longitudinal Profile of the Leading Edge

    NASA Astrophysics Data System (ADS)

    Mori, Warren; Tzoufras, Michail; Tsung, Frank; Sahai, Aakash

    2013-10-01

    Self-guiding of an ultra-intense laser pulse requires the refractive index to build up rapidly to a sufficient value before the main body of the pulse passes by. For short single-frequency pulses this occurs within a plasma period and a large portion of the leading edge is subject to diffraction. Nevertheless, if the body of the pulse survives long enough, the concomitant changes in its spectral content result in highly localized absorption, such that a large amount of the energy of the leading edge of the pulse is absorbed before it can diffract. To illustrate these mechanisms and optimize laser wakefield accelerators we propose a pulse profile with a ``bulbous bow,'' that is a lower-intensity low-energy precursor, that can produce the necessary buildup for the index of refraction to guide the body of the laser. The wake-field behind such a pulse is more stable, contains more energy, is sustained longer, and the corresponding de-phasing length is extended.

  1. The Course of Pain Intensity in Patients Undergoing Herniated Disc Surgery: A 5-Year Longitudinal Observational Study

    PubMed Central

    Dorow, Marie; Löbner, Margrit; Stein, Janine; Pabst, Alexander; Konnopka, Alexander; Meisel, Hans J.; Günther, Lutz; Meixensberger, Jürgen; Stengler, Katarina; König, Hans-Helmut; Riedel-Heller, Steffi G.

    2016-01-01

    Objectives The aims of this study are to answer the following questions (1) How does the pain intensity of lumbar and cervical disc surgery patients change within a postoperative time frame of 5 years? (2) Which sociodemographic, medical, work-related, and psychological factors are associated with postoperative pain in lumbar and cervical disc surgery patients? Methods The baseline survey (T0; n = 534) was conducted 3.6 days (SD 2.48) post-surgery in the form of face-to-face interviews. The follow-up interviews were conducted 3 months (T1; n = 486 patients), 9 months (T2; n = 457), 15 months (T3; n = 438), and 5 years (T4; n = 404) post-surgery. Pain intensity was measured on a numeric rating-scale (NRS 0–100). Estimated changes to and influences on postoperative pain by random effects were accounted by regression models. Results Average pain decreased continuously over time in patients with lumbar herniated disc (Wald Chi² = 25.97, p<0.001). In patients with cervical herniated disc a reduction of pain was observed, albeit not significant (Chi² = 7.02, p = 0.135). Two predictors were associated with postoperative pain in lumbar and cervical disc surgery patients: the subjective prognosis of gainful employment (p<0.001) and depression (p<0.001). Conclusion In the majority of disc surgery patients, a long-term reduction of pain was observed. Cervical surgery patients seemed to benefit less from surgery than the lumbar surgery patients. A negative subjective prognosis of gainful employment and stronger depressive symptoms were associated with postoperative pain. The findings may promote multimodal rehabilitation concepts including psychological and work-related support. PMID:27243810

  2. Summary of the RHIC Retreat 2008

    SciTech Connect

    Pilat,F.; Brennan, M.; Brown, K.; Fischer, W.; Montag, C.

    2008-08-01

    The main goal of the RHIC Retreat is to review last run's performance and prepare for the next. As always though we also discussed the longer term goals and plans for the facility to put the work in perspective and in the right priority. A straw-man plan for the facility was prepared for the DOE that assumes 30 cryoweek and running 2 species per year. The plan outlines RHIC operations for 2008-2012 and integrates well accelerator and detector upgrades to optimize the physics output with high luminosities. The plans includes guidance from the PAC and has been reviewed by DOE.

  3. COMPARATIVE SEM EVALUATION OF THREE SOLVENTS USED IN ENDODONTIC RETREATMENT: AN EX VIVO STUDY

    PubMed Central

    Scelza, Miriam F. Zaccaro; Coil, Jeffrey M.; Maciel, Ana Carolina de Carvalho; Oliveira, Lílian Rachel L.; Scelza, Pantaleo

    2008-01-01

    This study compared, by scanning electron microscopy (SEM), the efficacy of three solvents on the removal of filling materials from dentinal tubules during endodontic retreatment. Forty human maxillary canines with straight canals were prepared according to a crown-down technique and enlarged to a#30 apical file size, before obturation with gutta-percha and a zinc-oxide-eugenol based sealer. The samples were stored for 3 months before being randomly assigned to four groups: chloroform (n=10), orange oil (n=10), eucalyptol (n=10) and control (n=10). Solvents were applied to a reservoir created on the coronal root third using Gates Glidden drills. The total time for retreatment using the solvents was 5 minutes per tooth. Following retreatment the roots were split longitudinally for SEM evaluation. SEM images were digitized, analyzed using Image ProPlus 4.5 software, and the number of dentinal tubules free of filling material from the middle and apical thirds was recorded. No significant difference was found among the solvent groups regarding the number of dentinal tubules free of root filling remnants in the middle and apical root thirds (p>0.05). However, the control group had fewer dentinal tubules free of filling material (p<0.05). Under the tested conditions, it may be concluded that there was no significant difference among the solvents used to obtain dentinal tubules free of filling material remnants. PMID:19089285

  4. Comparative SEM evaluation of three solvents used in endodontic retreatment: an ex vivo study.

    PubMed

    Scelza, Miriam F Zaccaro; Coil, Jeffrey M; Maciel, Ana Carolina de Carvalho; Oliveira, Lílian Rachel L; Scelza, Pantaleo

    2008-01-01

    This study compared, by scanning electron microscopy (SEM), the efficacy of three solvents on the removal of filling materials from dentinal tubules during endodontic retreatment. Forty human maxillary canines with straight canals were prepared according to a crown-down technique and enlarged to a#30 apical file size, before obturation with gutta-percha and a zinc-oxide-eugenol based sealer. The samples were stored for 3 months before being randomly assigned to four groups: chloroform (n=10), orange oil (n=10), eucalyptol (n=10) and control (n=10). Solvents were applied to a reservoir created on the coronal root third using Gates Glidden drills. The total time for retreatment using the solvents was 5 minutes per tooth. Following retreatment the roots were split longitudinally for SEM evaluation. SEM images were digitized, analyzed using Image ProPlus 4.5 software, and the number of dentinal tubules free of filling material from the middle and apical thirds was recorded. No significant difference was found among the solvent groups regarding the number of dentinal tubules free of root filling remnants in the middle and apical root thirds (p>0.05). However, the control group had fewer dentinal tubules free of filling material (p<0.05). Under the tested conditions, it may be concluded that there was no significant difference among the solvents used to obtain dentinal tubules free of filling material remnants. PMID:19089285

  5. Latest Word on Retreat of the West Antarctic Ice Sheet

    NASA Technical Reports Server (NTRS)

    Bindschadler, R.

    2000-01-01

    The West Antarctic ice sheet during the Last Glacial Maximum (LGM) is estimated to have been three times its present volume and to have extended close to the edge of the continental shelf Holocene retreat of this ice sheet in the Ross Sea began between 11,000 and 12,000 years ago. This history implies an average contribution of this ice sheet to sea level of 0.9 mm/a. Evidence of dateable past grounding line positions in the Ross sector are broadly consistent with a linear retreat model. However, inferred rates of retreat for some of these grounding line positions are not consistent with a linear retreat model. More rapid retreat approximately 7600 years ago and possible near-stability in the Ross Sea sector at present suggest a slow rate of initial retreat followed by a more rapid-than-average retreat during the late Holocene, returning to a near-zero rate of retreat currently. This model is also consistent with the mid-Holocene high stand observations of eustatic sea level. Recent compilation of Antarctic bed elevations (BEDMAP) illustrates that the LGM and present grounding lines occur in the shallowest waters, further supporting the model of a middle phase of rapid retreat bracketed by an older and a more recent phase of modest retreat. Extension of these hypotheses into the future make subsequent behavior of the West Antarctic ice sheet more difficult to predict but suggest that if it loses its hold on the present shallow bed, the final retreat of the ice sheet could be very rapid.

  6. Quantitative Analysis of Holocene Shoreline Retreat in Unconsolidated Sediment within the northern Puget Lowland, WA.

    NASA Astrophysics Data System (ADS)

    Rogers, H. E.; Swanson, T. W.

    2006-12-01

    The long-term retreat rate of Puget Sound shorelines derived from unconsolidated sediment is difficult to quantify because the geomorphic evidence used to establish prior shoreline positions (i.e., wave-cut platforms) is itself, subsequently eroded by submarine processes. Qualitative assessment of more recent shoreline retreat can be inferred by comparing the width of wave-cut platforms lying adjacent to the respective shorelines, bluff steepness, and vegetation age structure on the bluff slope. A quantitative assessment of Holocene shoreline retreat on southern Whidbey Island, WA is being completed using reconstructed longitudinal profiles of relict post-glacial channels. Prior to the establishment of vegetation on Whidbey Island, the relict channels are inferred to have formed almost instantaneously after deglaciation by groundwater sapping of the glacial sediment. The channels were graded to the post-glacial marine high- stand (~140-160 feet A.S.L. on south Whidbey Island) and became inactive when vegetated. Where shoreline retreat has been rapid, the post-glacial marine terrace has been eroded, but the head of the relict channel is still preserved. Using ground surveying techniques, inferences based on drumlinoid topography, and high resolution LIDAR imagery, it is possible to infer the original post-glacial shoreline position by extending the longitudinal profile of the remnant channel to a point that intersects the original post-glacial terrace elevation (140 ft). In addition to geomorphic evidence, we are testing whether cosmogenic isotope dating (Cl-36 and Be-10) can quantify recent erosion rates by dating the exposure age of residual till boulders eroded by wave processes and deposited as a lag on the wave-cut platform. Transects are being measured from different type localities exhibiting various degrees of retreat due to differences in shoreline energy and substrate properties (i.e., exposure to prevailing storm track, length of fetch and the bluff

  7. Do intramedullary spinal cord changes in signal intensity on MRI affect surgical opportunity and approach for cervical myelopathy due to ossification of the posterior longitudinal ligament?

    PubMed

    Sun, Qizhi; Hu, Hongwei; Zhang, Ying; Li, Yang; Chen, Linwei; Chen, Huajiang; Yuan, Wen

    2011-09-01

    Some controversy still exists over the optimal treatment time and the surgical approach for cervical myelopathy due to ossification of the posterior longitudinal ligament (OPLL). The aim of the current study was first to analyze the effect of intramedullary spinal cord changes in signal intensity (hyperintensity on T2-weighted imaging and hypointensity on T1-weighted imaging) on magnetic resonance imaging (MRI) on surgical opportunity and approach for cervical myelopathy due to OPLL. This was a prospective randomized controlled study. Fifty-six patients with cervical myelopathy due to OPLL were enrolled and assigned to either group A (receiving anterior decompression and fusion, n = 27) or group P (receiving posterior laminectomy, n = 29). All the patients were followed up for an average 20.3 months (12-34 months). The clinical outcomes were assessed by the average operative time, blood loss, Japanese Orthopedic Association (JOA) score, improvement rate (IR) and complication. To determine the relevant statistics, we made two factorial designs and regrouped the data of all patients to group H (with hyperintensity on MRI, n = 31), group L (with hypointensity on MRI, n = 19) and group N (no signal on MRI, n = 25), and then to further six subgroups as well: AH (with hyperintensity on MRI from group A, n = 15), PH (with hyperintensity on MRI from group P, n = 16), AL (with hypointensity on MRI from group A, n = 10), PL (with hypointensity on MRI from group P, n = 9), AN (no signal intensity on MRI from group A, n = 12) and PN (no signal intensity on MRI from group P, n = 13). Both hyperintensity on T2-weighted imaging and hypointensity on T1-weighted imaging had a close relationship with the JOA score and IR. The pre- and postoperative JOA score and postoperative IR of either group H or group L was significantly lower than that of group N (P < 0.05), regardless of whether the patients had received anterior or posterior surgery. On the other hand, both the JOA score and

  8. Psychiatric Symptoms and Acute Care Service Utilization over the Course of the Year Following Medical-Surgical Intensive Care Unit Admission: A Longitudinal Investigation

    PubMed Central

    Davydow, Dimitry S.; Hough, Catherine L.; Zatzick, Douglas; Katon, Wayne J.

    2014-01-01

    Objective To determine if the presence of in-hospital substantial acute stress symptoms, as well as substantial depressive or posttraumatic stress disorder (PTSD) symptoms at 3-months post-intensive care unit (ICU), are associated with increased acute care service utilization over the course of the year following medical-surgical ICU admission. Design Longitudinal cohort study. Setting Academic medical center. Patients 150 patients ≥ 18 years old admitted to medical-surgical ICUs for over 24 hours. Measurements and Main Results Participants were interviewed in-hospital to ascertain substantial acute stress symptoms using the PTSD Checklist-civilian version (PCL-C). Substantial depressive and PTSD symptoms were assessed using the Patient Health Questionnaire-9 and the PCL-C respectively at 3 months post-ICU. The number of rehospitalizations and emergency room (ER) visits were ascertained at 3 and 12 months post-ICU using the Cornell Services Index. After adjusting for participant and clinical characteristics, in-hospital substantial acute stress symptoms were independently associated with greater risk of an additional hospitalization (Relative Risk [RR]: 3.00, 95% Confidence Interval [CI]: 1.80, 4.99) over the year post-ICU. Substantial PTSD symptoms at 3 months post-ICU were independently associated with greater risk of an additional ER visit during the subsequent 9 months (RR: 2.29, 95%CI: 1.09, 4.84) even after adjusting for both rehospitalizations and ER visits between the index hospitalization and 3 months post-ICU. Conclusions Post-ICU psychiatric morbidity is associated with increased acute care service utilization during the year after a medical-surgical ICU admission. Early interventions for at-risk ICU survivors may improve longer-term outcomes and reduce subsequent acute care utilization. PMID:25083985

  9. Quality of Life and Survival Outcome for Patients With Nasopharyngeal Carcinoma Receiving Three-Dimensional Conformal Radiotherapy vs. Intensity-Modulated Radiotherapy-A Longitudinal Study

    SciTech Connect

    Fang, F.-M. Chien, C.-Y.; Tsai, W.-L.; Chen, H.-C.; Hsu, H.-C.; Lui, C.-C.; Huang, T.-L.

    2008-10-01

    Purpose: To investigate the changes of quality of life (QoL) and survival outcomes for patients with nasopharyngeal carcinoma (NPC) treated by three-dimensional conformal radiotherapy (3D-CRT) vs. intensity-modulated radiotherapy (IMRT). Methods and Materials: Two hundred and three newly diagnosed NPC patients, who were curatively treated by 3D-CRT (n = 93) or IMRT (n = 110) between March 2002 and July 2004, were analyzed. The distributions of clinical stage according to American Joint Committee on Cancer 1997 were I: 15 (7.4%), II: 78 (38.4%), III: 74 (36.5%), and IV: 36 (17.7%). QoL was longitudinally assessed by the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 and the EORTC QLQ-H and N35 questionnaires at the five time points: before RT, during RT (36 Gy), and 3 months, 12 months, and 24 months after RT. Results: The 3-year locoregional control, metastasis-free survival, and overall survival rates were 84.8%, 76.7%, and 81.7% for the 3D-CRT group, respectively, compared with 84.2%, 82.6%, and 85.4% for the IMRT group (p value > 0.05). A general trend of maximal deterioration in most QoL scales was observed during RT, followed by a gradual recovery thereafter. There was no significant difference in most scales between the two groups at each time point. The exception was that patients treated by IMRT had a both statistically and clinically significant improvement in global QoL, fatigue, taste/smell, dry mouth, and feeling ill at the time point of 3 months after RT. Conclusions: The potential advantage of IMRT over 3D-CRT in treating NPC patients might occur in QoL outcome during the recovery phase of acute toxicity.

  10. Student Leadership Retreat Focusing on a Commitment to Excellence

    PubMed Central

    Traynor, Andrew P.; Sorensen, Todd D.

    2009-01-01

    Objective To design and evaluate a student leadership retreat focused on: leadership regardless of position or title, the need for passionate commitment to excellence, the importance of teamwork, and the value of self-reflection. Design Students in their second, third, and fourth year of a doctor of pharmacy (PharmD) program were invited to participate in an off-campus leadership retreat that combined organized learning activities and social/networking opportunities. Retreat content utilized didactic, experiential, and self-directed learning activities. Assessment Forty-two students participated in the retreat and were surveyed pre- and post-retreat. A student-led group evaluation and course evaluations were also utilized. Responses on the post-retreat evaluation suggested an increased belief in their ability to influence change and an enhanced awareness of the role of self-reflection in creating excellence in the profession. Conclusion An off-campus overnight retreat has value in challenging student perceptions about leadership and promoting reflection on their personal role in leading change within the profession Continued exploration and development of this format is warranted for commitment to excellence programming and also for additional leadership topics and audiences. PMID:19564991

  11. Modelling Glacier Retreat after Ice Shelf Collapse

    NASA Astrophysics Data System (ADS)

    De Rydt, J.; Gudmundsson, G. H.; Rott, H.; Bamber, J. L.

    2014-12-01

    Satellite measurements have shown the consistent and ongoing speed-up and retreat of glaciers that were once buttressed by the collapsed Larsen B ice shelf. Understanding the response of grounded ice to ice shelf collapse is a prerequisite to future predictions of sea level rise as other ice shelfs such as Scar Inlet or the Larsen Ice Shelf further weaken due to changing atmospheric and ocean conditions.We present model results for a number of sensitivity experiments that aim to simulate the response of glaciers to the collapse of Larsen B. For this purpose we use a state of the art shallow shelf model with grounding line resolving capabilities. The model is initialized to observed pre-2002 conditions with the ice shelf in place, and transient runs are done that study the response to a weakening and removal of the ice shelf. Results are compared to a novel dataset of observed ice velocities, which provides the most comprehensive overview of dynamical changes after the collapse to-date. In addition, we investigate glacier response to the future collapse of Scar Inlet, a remnant of the Larsen B ice shelf which has been suggested to show signs of weakening in recent years. Results will also be used to inform a future Antartic Peninsula-wide modelling study.

  12. Seaweed communities in retreat from ocean warming.

    PubMed

    Wernberg, Thomas; Russell, Bayden D; Thomsen, Mads S; Gurgel, C Frederico D; Bradshaw, Corey J A; Poloczanska, Elvira S; Connell, Sean D

    2011-11-01

    In recent decades, global climate change [1] has caused profound biological changes across the planet [2-6]. However, there is a great disparity in the strength of evidence among different ecosystems and between hemispheres: changes on land have been well documented through long-term studies, but similar direct evidence for impacts of warming is virtually absent from the oceans [3, 7], where only a few studies on individual species of intertidal invertebrates, plankton, and commercially important fish in the North Atlantic and North Pacific exist. This disparity of evidence is precarious for biological conservation because of the critical role of the marine realm in regulating the Earth's environmental and ecological functions, and the associated socioeconomic well-being of humans [8]. We interrogated a database of >20,000 herbarium records of macroalgae collected in Australia since the 1940s and documented changes in communities and geographical distribution limits in both the Indian and Pacific Oceans, consistent with rapid warming over the past five decades [9, 10]. We show that continued warming might drive potentially hundreds of species toward and beyond the edge of the Australian continent where sustained retreat is impossible. The potential for global extinctions is profound considering the many endemic seaweeds and seaweed-dependent marine organisms in temperate Australia. PMID:22036178

  13. Calculating lunar retreat rates using tidal rhythmites

    USGS Publications Warehouse

    Kvale, E.P.; Johnson, H.W.; Sonett, C.P.; Archer, A.W.; Zawistoski, A.N.N.

    1999-01-01

    Tidal rhythmites are small-scale sedimenta??r}- structures that can preserve a hierarchy of astronomically induced tidal periods. They can also preserve a record of periodic nontidal sedimentation. If properly interpreted and understood, tidal rhjthmites can be an important component of paleoastronomy and can be used to extract information on ancient lunar orbital dynamics including changes in Earth-Moon distance through geologic time. Herein we present techniques that can be used to calculate ancient Earth-Moon distances. Each of these techniques, when used on a modern high-tide data set, results in calculated estimates of lunar orbital periods and an EarthMoon distance that fall well within 1 percent of the actual values. Comparisons to results from modern tidal data indicate that ancient tidal rhythmite data as short as 4 months can provide suitable estimates of lunar orbital periods if these tidal records are complete. An understanding of basic tidal theory allows for the evaluation of completeness of the ancient tidal record as derived from an analysis of tidal rhythmites. Utilizing the techniques presented herein, it appears from the rock record that lunar orbital retreat slowed sometime during the midPaleozoic. Copyright ??1999, SEPM (Society for Sedimentary Geology).

  14. Signatures of Glacial Erosion and Retreat in the Landscape: Cosmogenic and Numerical Modeling Constraints

    NASA Astrophysics Data System (ADS)

    Ward, D. J.; Anderson, R. S.; Briner, J. P.; Guido, Z. S.

    2006-12-01

    The response of glaciers to past climatic change is important for understanding 1) observations of modern glaciers under currently changing climate conditions, and 2) long-term effects on the landscape of repeated glacial occupation and retreat. The complex dynamics of these systems require that multiple lines of data constrain models of glacial behavior and erosion. Toward this end, we use cosmogenic radionuclide (CRN) exposure ages to constrain numerical simulations of glacier advance and retreat histories in the Middle Boulder Creek drainage, Colorado Front Range, and the Animas River valley, San Juan Mountains, Colorado. We present ~12 new 10Be exposure ages from glacially polished bedrock sampled in the Middle Boulder Creek valley. All of these ages are younger than a ~17 ka 10Be terminal moraine age reported by Schildgen and Dethier (2002). Ages appear to decrease monotonically with distance upvalley from the moraine, and the youngest ages in the uppermost valley are uniformly ~10 ka. We include 5 10Be ages in a cross section across the mid-valley, which show a pattern of Last Glacial Maximum (LGM) ages (11-14 ka) within the glacial footprint, and older exposure ages (~40 ka) near the trim lines. A similar age trend is seen in the Animas River valley in southwestern Colorado, which was occupied by a lobe of the LGM ice sheet that capped the San Juan mountains. Deglaciation began here ca. 18.7 ka, based on a 10Be depth profile in a proglacial terrace. A longitudinal transect of exposure ages from glacially polished samples indicates that terminus retreat proceeded at 6-9 m/yr until complete deglaciation ca. 9.5 ka. Neither valley has obvious recessional deposits within the LGM glacial footprint. The first-order trend in each valley is a monotonic glacial retreat, but there are other possible retreat scenarios. For instance, we would like to test whether the same trend in 10Be concentrations could be generated by episodic retreat punctuated by periods of

  15. Level of Cigarette Consumption and Quit Behavior in a Population of Low-Intensity Smokers – Longitudinal Results from the International Tobacco Control (ITC) Survey in Mexico

    PubMed Central

    Swayampakala, Kamala; Thrasher, James; Carpenter, Matthew J.; Shigematsu, Luz Myriam Reynales; Cupertio, Ana-Paula; Berg, Carla J.

    2013-01-01

    Background Mexican smokers are more likely to be non-daily smokers and to consume fewer cigarettes per day than smokers in other countries. Little is known about their quit behaviors. Aim The aim of this study is to determine factors associated with having made a quit attempt and being successfully quit at 14-month follow-up in a population-based cohort of adult Mexicans who smoke at different levels of intensity. Design A longitudinal analysis of wave-III and wave-IV (2010) Mexican administration of International Tobacco Control Policy Evaluation Project was conducted. Setting This study was conducted in six large urban centers in Mexico Participants The participants of this study comprised 1206 adults who were current smokers at wave-III and 41 who were followed to wave-IV. Measurements We compared three groups of smokers: non-daily smokers—who did not smoke every day in the past 30 days (n=398), daily light smokers who smoked every day at a rate of ≤5 cigarettes per day. Data on smoking behavior, psychosocial characteristics and socio-demographics were collected at baseline and after 14 months. Findings In multivariate logistic regression predicting having made a quit attempt at follow-up, significant factors included being a non-daily smoker versus a heavy daily smoker (ORadj = 1.83, 95%CI: 1.19–2.83), less perceived addiction ((ORadj = 1.86, 95%CI: 1.20 – 2.87), greater worry that cigarettes will damage health (ORadj = 2.04, 95%CI: 1.16 – 3.61) and having made a quit attempt in the past year at baseline (ORadj = 1.70, 95%CI: 1.23 – 2.36). In multivariate logistic regression predicting being successfully quit at one-year follow-up, significant factors included being a non-daily smoker versus a heavy daily smoker (ORadj = 2.54, 95%CI: 1.37–4.70) and less perceived addiction (not addicted: ORadj = 3.26, 95%CI: 1.73 – 6.14; not much: ORadj = 1.95, 95%CI: 1.05 – 3.62 versus very much). Conclusions Mexican adult smokers who are non-daily smokers

  16. Patient-Reported Voice and Speech Outcomes After Whole-Neck Intensity Modulated Radiation Therapy and Chemotherapy for Oropharyngeal Cancer: Prospective Longitudinal Study

    SciTech Connect

    Vainshtein, Jeffrey M.; Griffith, Kent A.; Feng, Felix Y.; Vineberg, Karen A.; Chepeha, Douglas B.; Eisbruch, Avraham

    2014-08-01

    Purpose: To describe voice and speech quality changes and their predictors in patients with locally advanced oropharyngeal cancer treated on prospective clinical studies of organ-preserving chemotherapy–intensity modulated radiation therapy (chemo-IMRT). Methods and Materials: Ninety-one patients with stage III/IV oropharyngeal cancer were treated on 2 consecutive prospective studies of definitive chemoradiation using whole-field IMRT from 2003 to 2011. Patient-reported voice and speech quality were longitudinally assessed from before treatment through 24 months using the Communication Domain of the Head and Neck Quality of Life (HNQOL-C) instrument and the Speech question of the University of Washington Quality of Life (UWQOL-S) instrument, respectively. Factors associated with patient-reported voice quality worsening from baseline and speech impairment were assessed. Results: Voice quality decreased maximally at 1 month, with 68% and 41% of patients reporting worse HNQOL-C and UWQOL-S scores compared with before treatment, and improved thereafter, recovering to baseline by 12-18 months on average. In contrast, observer-rated larynx toxicity was rare (7% at 3 months; 5% at 6 months). Among patients with mean glottic larynx (GL) dose ≤20 Gy, >20-30 Gy, >30-40 Gy, >40-50 Gy, and >50 Gy, 10%, 32%, 25%, 30%, and 63%, respectively, reported worse voice quality at 12 months compared with before treatment (P=.011). Results for speech impairment were similar. Glottic larynx dose, N stage, neck dissection, oral cavity dose, and time since chemo-IMRT were univariately associated with either voice worsening or speech impairment. On multivariate analysis, mean GL dose remained independently predictive for both voice quality worsening (8.1%/Gy) and speech impairment (4.3%/Gy). Conclusions: Voice quality worsening and speech impairment after chemo-IMRT for locally advanced oropharyngeal cancer were frequently reported by patients, underrecognized by clinicians, and

  17. How fast do gully headcuts retreat?

    NASA Astrophysics Data System (ADS)

    Vanmaercke, Matthias; Poesen, Jean

    2015-04-01

    Gullies can be a dominant sediment source at field and catchment scales. Over the past decades, several studies have been conducted that quantify gully headcut retreat (GHR) in different environments. Although this led to important site-specific and regional insights, the overall importance of this erosion process or the factors that control it at a global scale remain poorly understood. This study aims to bridge this gap by conducting a meta-analysis of measured GHR rates worldwide. Through an extensive literature review, GHR rates for ca. 900 individual actively retreating gullies (comprising a total measuring period of > 19 000 years) from more than 50 study areas worldwide have been compiled. Each GHR rate was measured by means of repeated field surveys and/or analyses of aerial photographs over a period of at least one year. The collected data shows a very large variability, both in terms of gully dimensions (cross-sectional areas ranging between 0.11 and 816 m² with a median of 4 m²) and GHR rates (ranging between 0.003 and 47 000 m³/y with a median of 2.2 m³/y). Linear GHR rates vary between 0.01 and 70 m/y (median: 0.82 m/y). By means of statistical analyses for a subset of 689 gullies with a known contributing area, we explored which factors are most relevant in explaining the observed 6 orders of magnitudes of variation in volumetric GHR rates. Results show that measured GHR rates are significantly correlated to the runoff contributing area of the gully (r² = 0.13) and the average rainfall depth on a rainy day (i.e. the long-term average annual rainfall depth divided by the average number of rainy days; r² = 0.39). Combined, these two factors explained 57% of the observed variability in average GHR rates. Other factors (e.g. land use or soil type) showed no significant correlation with the observed GHR rates. This may be attributed to the uncertainties associated with accurately quantifying these factors. In addition, a large part of the remaining

  18. Rituximab Retreatment for Low-Tumor Burden Follicular Lymphoma

    Cancer.gov

    A summary of results from a randomized clinical trial of patients with low–tumor burden follicular lymphoma that compared maintenance therapy with rituximab versus retreatment with rituximab only when there was evidence of disease progression.

  19. Parallel retreat of rock slopes underlain by alternation of strata

    NASA Astrophysics Data System (ADS)

    Imaizumi, Fumitoshi; Nishii, Ryoko; Murakami, Wataru; Daimaru, Hiromu

    2015-06-01

    Characteristic landscapes (e.g., cuesta, cliff and overhang of caprock, or stepped terrain) formed by differential erosion can be found in areas composed of variable geology exhibiting different resistances to weathering. Parallel retreat of slopes, defined as recession of slopes without changes in their topography, is sometimes observed on slopes composed of multiple strata. However, the conditions needed for such parallel retreat have not yet been sufficiently clarified. In this study, we elucidated the conditions for parallel retreat of rock slopes composed of alternating layers using a geometric method. In addition, to evaluate whether various rock slopes fulfilled the conditions for parallel retreat, we analyzed topographic data obtained from periodic measurement of rock slopes in the Aka-kuzure landslide, central Japan. Our geometric analysis of the two-dimensional slopes indicates that dip angle, slope gradient, and erosion rate are the factors that determine parallel retreat conditions. However, dip angle does not significantly affect parallel retreat conditions in the case of steep back slopes (slope gradient > 40°). In contrast, dip angle is an important factor when we consider the parallel retreat conditions in dip slopes and gentler back slopes (slope gradient < 40°). Geology in the Aka-kuzure landslide is complex because of faulting, folding, and toppling, but spatial distribution of the erosion rate measured by airborne LiDAR scanning and terrestrial laser scanning (TLS) roughly fulfills parallel retreat conditions. The Aka-kuzure landslide is characterized by repetition of steep sandstone cliffs and gentle shale slopes that form a stepped topography. The inherent resistance of sandstone to weathering is greater than that of shale. However, the vertical erosion rate within the sandstone was higher than that within the shale, due to direct relationship between slope gradient and vertical erosion rate in the Aka-kuzure landslide.

  20. Climate change and glacier retreat drive shifts in an Antarctic benthic ecosystem.

    PubMed

    Sahade, Ricardo; Lagger, Cristian; Torre, Luciana; Momo, Fernando; Monien, Patrick; Schloss, Irene; Barnes, David K A; Servetto, Natalia; Tarantelli, Soledad; Tatián, Marcos; Zamboni, Nadia; Abele, Doris

    2015-11-01

    The Antarctic Peninsula (AP) is one of the three places on Earth that registered the most intense warming in the last 50 years, almost five times the global mean. This warming has strongly affected the cryosphere, causing the largest ice-shelf collapses ever observed and the retreat of 87% of glaciers. Ecosystem responses, although increasingly predicted, have been mainly reported for pelagic systems. However, and despite most Antarctic species being benthic, responses in the Antarctic benthos have been detected in only a few species, and major effects at assemblage level are unknown. This is probably due to the scarcity of baselines against which to assess change. We performed repeat surveys of coastal benthos in 1994, 1998, and 2010, analyzing community structure and environmental variables at King George Island, Antarctica. We report a marked shift in an Antarctic benthic community that can be linked to ongoing climate change. However, rather than temperature as the primary factor, we highlight the resulting increased sediment runoff, triggered by glacier retreat, as the potential causal factor. The sudden shift from a "filter feeders-ascidian domination" to a "mixed assemblage" suggests that thresholds (for example, of tolerable sedimentation) and alternative equilibrium states, depending on the reversibility of the changes, could be possible traits of this ecosystem. Sedimentation processes will be increasing under the current scenario of glacier retreat, and attention needs to be paid to its effects along the AP. PMID:26702429

  1. Plasticity of visual attention in Isha yoga meditation practitioners before and after a 3-month retreat.

    PubMed

    Braboszcz, Claire; Cahn, B Rael; Balakrishnan, Bhavani; Maturi, Raj K; Grandchamp, Romain; Delorme, Arnaud

    2013-01-01

    Meditation has lately received considerable interest from cognitive neuroscience. Studies suggest that daily meditation leads to long lasting attentional and neuronal plasticity. We present changes related to the attentional systems before and after a 3 month intensive meditation retreat. We used three behavioral psychophysical tests - a Stroop task, an attentional blink task, and a global-local letter task-to assess the effect of Isha yoga meditation on attentional resource allocation. 82 Isha yoga practitioners were tested at the beginning and at the end of the retreat. Our results showed an increase in correct responses specific to incongruent stimuli in the Stroop task. Congruently, a positive correlation between previous meditation experience and accuracy to incongruent Stroop stimuli was also observed at baseline. We also observed a reduction of the attentional blink. Unexpectedly, a negative correlation between previous meditation experience and attentional blink performance at baseline was observed. Regarding spatial attention orientation as assessed using the global-local letter task, participants showed a bias toward local processing. Only slight differences in performance were found pre- vs. post- meditation retreat. Biasing toward the local stimuli in the global-local task and negative correlation of previous meditation experience with attentional blink performance is consistent with Isha practices being focused-attention practices. Given the relatively small effect sizes and the absence of a control group, our results do not allow clear support nor rejection of the hypothesis of meditation-driven neuronal plasticity in the attentional system for Isha yoga practice. PMID:24376429

  2. Climate change and glacier retreat drive shifts in an Antarctic benthic ecosystem

    PubMed Central

    Sahade, Ricardo; Lagger, Cristian; Torre, Luciana; Momo, Fernando; Monien, Patrick; Schloss, Irene; Barnes, David K. A.; Servetto, Natalia; Tarantelli, Soledad; Tatián, Marcos; Zamboni, Nadia; Abele, Doris

    2015-01-01

    The Antarctic Peninsula (AP) is one of the three places on Earth that registered the most intense warming in the last 50 years, almost five times the global mean. This warming has strongly affected the cryosphere, causing the largest ice-shelf collapses ever observed and the retreat of 87% of glaciers. Ecosystem responses, although increasingly predicted, have been mainly reported for pelagic systems. However, and despite most Antarctic species being benthic, responses in the Antarctic benthos have been detected in only a few species, and major effects at assemblage level are unknown. This is probably due to the scarcity of baselines against which to assess change. We performed repeat surveys of coastal benthos in 1994, 1998, and 2010, analyzing community structure and environmental variables at King George Island, Antarctica. We report a marked shift in an Antarctic benthic community that can be linked to ongoing climate change. However, rather than temperature as the primary factor, we highlight the resulting increased sediment runoff, triggered by glacier retreat, as the potential causal factor. The sudden shift from a “filter feeders–ascidian domination” to a “mixed assemblage” suggests that thresholds (for example, of tolerable sedimentation) and alternative equilibrium states, depending on the reversibility of the changes, could be possible traits of this ecosystem. Sedimentation processes will be increasing under the current scenario of glacier retreat, and attention needs to be paid to its effects along the AP. PMID:26702429

  3. Hasty retreat of glaciers in northern Patagonia

    NASA Astrophysics Data System (ADS)

    Paul, Frank; Mölg, Nico

    2014-05-01

    decline (area and thickness loss). Some glaciers retreated more than 3 km over this time period or even disappeared completely. Typically, these glaciers lost contact to the accumulation areas of tributaries and melted away as dead ice. Furthermore, numerous proglacial lakes formed or expanded rapidly, increasing the local hazard potential. On the other hand, some glaciers located on or near to (still active) volcanoes have also slightly advanced over the same time period. Observed trends in temperature (decreasing) are in contrast to the observed strong glacier shrinkage, indicating that also other factors must play a role.

  4. Signatures of Glacial Erosion and Retreat in the Landscape: Cosmogenic and Numerical Modeling Constraints

    NASA Astrophysics Data System (ADS)

    Ward, D. J.; Anderson, R. S.; Briner, J. P.; Guido, Z. S.

    2007-12-01

    We use cosmogenic radionuclide (CRN) exposure ages to constrain numerical simulations of deglaciation histories in the Middle Boulder Creek drainage, Colorado Front Range, and the Animas River valley, San Juan Mountains, Colorado. We present 18 new 10Be exposure ages from glacially polished bedrock sampled in the Middle Boulder Creek valley. All of these ages are younger than the ~19-22 ka terminal moraine age based on 26Al and 36Cl measurements by Schildgen (2000) and Benson et al. (2005). Exposure ages decrease with distance upvalley from the moraine, and the youngest ages in the uppermost valley are uniformly ~13 ka. We include 4 10Be ages in a cross section across the mid-valley, which show a pattern of Last Glacial Maximum (LGM) ages (12-14 ka) within the glacial footprint, and older exposure ages (~40 ka) near the trim lines. A similar age trend is seen in the Animas River valley in southwestern Colorado, which was occupied by a lobe of the LGM ice sheet that capped the San Juan mountains. Deglaciation began here ca. 19.4 ka, based on a 10Be depth profile in a proglacial terrace. A longitudinal transect of exposure ages from glacially polished samples indicates that terminus retreat proceeded at ~15 m/yr until complete deglaciation ca. 12.3 ka. Neither valley has obvious recessional deposits within the LGM glacial footprint. The first-order trend in each valley is a monotonic glacial retreat, but there are other possible retreat scenarios. For instance, we would like to test whether the same trend in 10Be concentrations could be generated by episodic retreat punctuated by periods of readvance. To investigate these scenarios, we modified the GC2D numerical glacier simulation (see Kessler et al., 2006) to incorporate a CRN accumulation layer. This layer can contain any starting value of CRN concentration. Production over each timestep is scaled to DEM latitude and altitude. Production is taken to be zero in areas covered by more than 10 m of ice. The CRN

  5. Endodontic retreatment. Aspects of decision making and clinical outcome.

    PubMed

    Kvist, T

    2001-01-01

    Epidemiological surveys have reported that 25%-35% of root filled teeth are associated with periapical radiolucencies. Descriptive studies have demonstrated that clinicians' decision making regarding such teeth are subject to substantial variation. A coherent model to explain the observed variation has not been produced. In the present thesis a "Praxis Concept theory" was proposed. The theory suggests that dentists perceive periapical lesions of varying sizes as different stages on a continuous health scale. Interindividual variations can then be regarded as the result of the choice of different cut-off points on the continuum for prescribing retreatment. In the present study experiments among novice and expert decision makers gave evidence in favour of the theory. Data also suggested that the choice of retreatment criterion is affected by values, costs of retreatment and technical quality of original treatment. From a prescriptive point of view, the presence of a persistent periapical radiolucency has often been used as a criterion of endodontic "failure" and as an indication for endodontic retreatment. As an alternative decision strategy, the use of decision analysis has been proposed. Logical display of decision alternatives, values of probabilities, utility values (U-values) of the different outcomes and calculation of optimal decision strategy are features of this theory. The implementation of this approach is impeded by the uncertainty of outcome probabilities and lack of investigations concerning U-values. U-values of two periapical health states in root filled teeth (with and without a periapical lesion respectively) were investigated in a group of 82 dental students and among 16 Swedish endodontists. Two methods were used to elicit U-values: Standard gamble and Visual Analogue Scale. Large interindividual variation for both health states were recorded. The difference in U-values between the two health states was found to be statistically significant

  6. Ocean forcing of glacier retreat in the western Antarctic Peninsula

    NASA Astrophysics Data System (ADS)

    Cook, A. J.; Holland, P. R.; Meredith, M. P.; Murray, T.; Luckman, A.; Vaughan, D. G.

    2016-07-01

    In recent decades, hundreds of glaciers draining the Antarctic Peninsula (63° to 70°S) have undergone systematic and progressive change. These changes are widely attributed to rapid increases in regional surface air temperature, but it is now clear that this cannot be the sole driver. Here, we identify a strong correspondence between mid-depth ocean temperatures and glacier-front changes along the ~1000-kilometer western coastline. In the south, glaciers that terminate in warm Circumpolar Deep Water have undergone considerable retreat, whereas those in the far northwest, which terminate in cooler waters, have not. Furthermore, a mid-ocean warming since the 1990s in the south is coincident with widespread acceleration of glacier retreat. We conclude that changes in ocean-induced melting are the primary cause of retreat for glaciers in this region.

  7. Ocean forcing of glacier retreat in the western Antarctic Peninsula.

    PubMed

    Cook, A J; Holland, P R; Meredith, M P; Murray, T; Luckman, A; Vaughan, D G

    2016-07-15

    In recent decades, hundreds of glaciers draining the Antarctic Peninsula (63° to 70°S) have undergone systematic and progressive change. These changes are widely attributed to rapid increases in regional surface air temperature, but it is now clear that this cannot be the sole driver. Here, we identify a strong correspondence between mid-depth ocean temperatures and glacier-front changes along the ~1000-kilometer western coastline. In the south, glaciers that terminate in warm Circumpolar Deep Water have undergone considerable retreat, whereas those in the far northwest, which terminate in cooler waters, have not. Furthermore, a mid-ocean warming since the 1990s in the south is coincident with widespread acceleration of glacier retreat. We conclude that changes in ocean-induced melting are the primary cause of retreat for glaciers in this region. PMID:27418507

  8. Comparison of the amount of apical debris extrusion associated with different retreatment systems and supplementary file application during retreatment process

    PubMed Central

    Çiçek, Ersan; Koçak, Mustafa Murat; Koçak, Sibel; Sağlam, Baran Can

    2016-01-01

    Background: The type of instrument affects the amount of debris extruded. The aim of this study was to compare the effect of retreatment systems and supplementary file application on the amount of apical debris extrusion. Materials and Methods: Forty-eight extracted mandibular premolars with a single canal and similar length were selected. The root canals were prepared with the ProTaper Universal system with a torque-controlled engine. The root canals were dried and were obturated using Gutta-percha and sealer. The specimens were randomly divided into four equal groups according to the retreatment procedures (Group 1, Mtwo retreatment files; Group 2, Mtwo retreatment files + Mtwo rotary file #30 supplementary file; Group 3, ProTaper Universal retreatment (PTUR) files; and Group 4, PTUR files + ProTaper F3 supplementary file). The extruded debris during instrumentation were collected into preweighed Eppendorf tubes. The amount of apically extruded debris was calculated by subtracting the initial weight of the tube from the final weight. Three consecutive weights were obtained for each tube. Results: No statistically significant difference was found in the amount of apically extruded debris between Groups 1 and 3 (P = 0.590). A significant difference was observed between Groups 1 and 2 (P < 0.05), and between Groups 3 and 4 (P < 0.05). Conclusions: The use of supplementary file significantly increased the amount of apically extruded debris. PMID:27563185

  9. The Time It Takes: A Longitudinal Study of the 2003 Cohort Eligible to Transfer to a Research Intensive University. Research Results

    ERIC Educational Resources Information Center

    Lavin, Tracy

    2011-01-01

    For a number of years, the Student Transitions Project (STP) has tracked the students in BC's public colleges, institutes and teaching intensive universities (CDW institutions) who are eligible to transfer (ETR) to any of the four research intensive universities in BC in the subsequent year (i.e., students who have completed or enrolled in at…

  10. The Relationship between Intensity and Breadth of After-School Program Participation and Academic Achievement: Evidence from a Short-Term Longitudinal Study

    ERIC Educational Resources Information Center

    Springer, Ken; Diffily, Deborah

    2012-01-01

    We explored the extent to which intensity and breadth of participation in an after-school program (ASP) predicted academic achievement, as measured by changes in grades and attendance. The sample comprised 719 2nd-grade through 8th-grade Boys and Girls Clubs of Greater Dallas members during the 2009-2010 academic year. With respect to intensity,…

  11. The Time It Takes: A Longitudinal Study of the 2003 Cohort of Students Eligible to Transfer to a BC Research Intensive University

    ERIC Educational Resources Information Center

    Lavin, Tracy

    2011-01-01

    The BC Transfer System allows students to attend public colleges, institutes and teaching intensive universities (i.e., Central Data Warehouse or CDW reporting institutions) throughout the province where they accumulate credits which they can transfer to research intensive universities and use to fulfill their degree requirements. The Student…

  12. Is rate of glacial retreat accelerated in Indian Himalaya? (Invited)

    NASA Astrophysics Data System (ADS)

    Kulkarni, A. V.

    2013-12-01

    The Himalaya has one of the largest concentration of glaciers and rivers like Indus, Ganga and Bramhputra originate from this region. The snow and glacier melt is an important source of water for these rivers. However, this source of water may get affected in the near future due to changes in the cryosphere. Therefore, retreat of Himalayan glaciers are discussed extensively in scientific and public forums in India. Conventionally health of glaciers is assessed using changes in glacial length, as it is widely measured. However changes in glacial length and loss in areal extent near terminus needs to be interpreted carefully, as these changes can be influenced by numerous terrain and climatically sensitive parameters. The terrain parameters which can influence glacial retreat are slope, area altitude distribution, debris cover and orientation. In addition, climatically sensitive parameters like mass balance, glacial lakes and black carbon can also influence glacier retreat. These multiple influences can produce a complex pattern of glacial retreat. In this paper long-term glacier retreat in three river basins in the Indian Himalaya as Tista, Baspa and Parbati will be discussed. These basins are located in different climatically sensitive regions and each basin has unique dominant process of mass wasting. In addition to terrain parameters, influence of process like formation and expansion of moraine dammed lakes in Tista basin, deposition of black carbon on accumulation area in Baspa basin and debris cover in Parbati basin will also be discussed. This will provide understanding on varying influence of different mass wasting processes on glacial retreat during last five decades in the Indian Himalaya.

  13. Quantifying global warming from the retreat of glaciers

    SciTech Connect

    Oerlemans, J. )

    1994-04-08

    Records of glacier fluctuations compiled by the World Glacier Monitoring Service can be used to derive an independent estimate of global warming during the last 100 years. Records of different glaciers are made comparable by a two-step scaling procedure; one allowing for differences in glacier geometry, the other for differences in climate sensitivity. The retreat of glaciers during the last 100 years appears to be coherent over the globe. On the basis of modeling of the climate sensitivity of glaciers, the observed glacier retreat can be explained by a linear warming trend of 0.66 kelvin per century.

  14. Promoting Writing for Research: The "Writing Retreat" Model

    ERIC Educational Resources Information Center

    Singh, R. J.

    2012-01-01

    Research papers take a long time to write and in an academic environment where the "publish or perish" clause applies, writing retreats are a way of creating time and space to write academic articles in a concentrated period of time. This article examines ways in which academics can write more articles for publication. In particular it focuses on…

  15. Scientists Discover New Possibilities at Scientific Investigators Retreat | Poster

    Cancer.gov

    By Nancy Parrish, Staff Writer; photos by Richard Frederickson, Staff Photographer Scientists who attended the 2015 NCI Intramural Scientific Investigators Retreat on Jan. 13 had a chance to discuss research results with other investigators from across the National Cancer Institute. And this year, they could also explore new possibilities for the future of their research.

  16. Strategic planning: it's worth the effort. Homework makes retreats work.

    PubMed

    Hansen, Richard D

    2003-09-01

    Medical groups that achieve superior operational and financial performance frequently have leaders who take time to hold strategic planning retreats. These gatherings allow practice leaders to address difficult issues such as expansion, compensation structure and governance--away from the workplace and facilitated by an outsider. The result: organizational direction that all leaders help shape and commit to. PMID:14535084

  17. Jumpstarting Junior Faculty Motivation and Performance with Focused Writing Retreats

    ERIC Educational Resources Information Center

    Girardeau, Laura; Rud, A. G.; Trevisan, Michael S.

    2014-01-01

    Faculty members are critical assets to universities, and large losses to institutions occur if they are not successful. Although institutions value publications and grants in the tenure process, newer professors receive little guidance in writing for these endeavors. Faculty writing retreats help apprentice professors in the craft of writing;…

  18. Exploring the Effectiveness of a Retreat Method for Extension Staff

    ERIC Educational Resources Information Center

    Worker, Steven M.; Hill, Russell D.; Miller, JoLynn C.; Go, Charles G.; Boyes, Rita J.

    2015-01-01

    The California 4-H Association hosted two retreats to support its members with goals of balancing professional development with intentional relationship building. Evaluations demonstrated that staff found the intentional balance of time spent in unstructured, semi-structured, and structured time offered opportunities to grow professionally while…

  19. Effects of errors in velocity tilt on maximum longitudinal compression during neutralized drift compression of intense beam pulses: I. general description

    SciTech Connect

    Kaganovich, Igor D.; Massidda, Scottt; Startsev, Edward A.; Davidson, Ronald C.; Vay, Jean-Luc; Friedman, Alex

    2012-06-21

    Neutralized drift compression offers an effective means for particle beam pulse compression and current amplification. In neutralized drift compression, a linear longitudinal velocity tilt (head-to-tail gradient) is applied to the non-relativistic beam pulse, so that the beam pulse compresses as it drifts in the focusing section. The beam current can increase by more than a factor of 100 in the longitudinal direction. We have performed an analytical study of how errors in the velocity tilt acquired by the beam in the induction bunching module limit the maximum longitudinal compression. It is found that the compression ratio is determined by the relative errors in the velocity tilt. That is, one-percent errors may limit the compression to a factor of one hundred. However, a part of the beam pulse where the errors are small may compress to much higher values, which are determined by the initial thermal spread of the beam pulse. It is also shown that sharp jumps in the compressed current density profile can be produced due to overlaying of different parts of the pulse near the focal plane. Examples of slowly varying and rapidly varying errors compared to the beam pulse duration are studied. For beam velocity errors given by a cubic function, the compression ratio can be described analytically. In this limit, a significant portion of the beam pulse is located in the broad wings of the pulse and is poorly compressed. The central part of the compressed pulse is determined by the thermal spread. The scaling law for maximum compression ratio is derived. In addition to a smooth variation in the velocity tilt, fast-changing errors during the pulse may appear in the induction bunching module if the voltage pulse is formed by several pulsed elements. Different parts of the pulse compress nearly simultaneously at the target and the compressed profile may have many peaks. The maximum compression is a function of both thermal spread and the velocity errors. The effects of the

  20. Characteristics and Treatment Outcomes of Retreatment Tuberculosis Patients in Benin

    PubMed Central

    Ade, Serge; Adjibodé, Omer; Wachinou, Prudence; Toundoh, Narcisse; Awanou, Bérénice; Agodokpessi, Gildas; Affolabi, Dissou; Adè, Gabriel; Harries, Anthony D.; Anagonou, Séverin

    2016-01-01

    Objective. To determine among retreatment tuberculosis patients in Benin baseline characteristics, culture, and drug sensitivity testing (DST) results and treatment outcomes. Materials and Methods. A retrospective national cohort study of all retreatment tuberculosis patients in Benin in 2013 using registers and treatment cards. Results. Of 3957 patients with tuberculosis, 241 (6%) were retreatment cases. Compared to new pulmonary bacteriologically confirmed tuberculosis (NPBCT) patients, there were significantly higher numbers of males (P = 0.04), patients from “Atlantique-Littoral” (P = 0.006), patients aged 45–64 years (P = 0.007), and HIV-positive patients (P = 0.04) among those retreated. Overall, 171 (71%) patients submitted sputum for DST, of whom (163) 95% were positive for Mycobacterium tuberculosis on Xpert MTB/RIF and/or culture and 17 (10%) were rifampicin resistant (9 with MDR-TB and 8 monoresistant to rifampicin). For those without MDR-TB (n = 224), treatment success was 93%. Worse outcomes occurred in those with unknown HIV status (RR: 0.27; 0.05–1.45; P < 0.01) while better outcomes occurred in those who relapsed (RR: 1.06, 95 CI: 1.02–1.10, P = 0.04). Conclusion. In 2013, a high proportion of retreatment patients received DST. Treatment success was good although more needs to be done to systematically increase the final follow-up smear examination. Reasons of high losses to follow-up from “Oueme-Plateau” should be investigated. PMID:27110400

  1. Surface and crustal expression of ocean subduction retreat vs delamination (sub-crustal retreat): Implications for the Apennines tectonics

    NASA Astrophysics Data System (ADS)

    Göğüş, Oğuz H.; Chiarabba, Claudio; Pysklywec, Russell; Faccenna, Claudio; Husson, Laurent

    2015-04-01

    Many geological and geophysical observations in the Mediterranean (Apennines-Tyrrhenian, Betic/Rif -Alboran, and the Hellenic-Aegean) orogenic belts postulate that syn-convergent extension may be a common geological processs in response to deep slab-mantle interactions. Two primary geodynamic processes have been suggested for the onset of lithospheric scale extension that occurs contemporaneous with shortening: (1) retreating ocean subduction with significant overriding plate extension/thinning (e.g back-arc basin formations); and (2) inferred post-collisional lithospheric delamination (sub-crustal retreat) following subduction retreat. In a series of computational geodynamic experiments, we quantitatively investigate the surface and crustal response to these two deep lithospheric thinning/removal mechanisms, identified by transient surface tectonics. Surface topography associated with retreating ocean subduction indicates a broad region of surface subsidence leading to the formation back-arc basin. Models of lithospheric delamination predict initially elevated surface topography due to hot mantle upwelling (after removal) then more localized surface depression with crustal weakening and gravitational collapse. In both retreat and delamination models, maximum surface subsidence occurs in response to the subduction/delamination slab mobilization but the delamination process may develop more rapidly depending on the weakness of the lower crust. The delamination hinge/subduction trench is associated with crustal shortening and extension/thinning in the "back-arc zone" due to the retro-ward motion of the hinge, although calculated stretching factors (β) are higher in delamination experiments. The thermal expression of extending back-arc zone in delamination experiments is dominated by significant thermal perturbation of the crust caused by the underlying sub-lithospheric mantle flow. With subduction retreat experiments, the amount of crustal heating is dependent on

  2. The effect of spiritual retreat on nurses' spirituality: a randomized controlled study.

    PubMed

    Bay, Paul S; Ivy, Steven S; Terry, Colin L

    2010-01-01

    This study tested whether two 1-day retreats focused on spiritual self-care would positively change nurse participants' spirituality. A total of 199 critical care nurses were accepted into this study; 87 were randomized to receive the retreat intervention. All 199 nurses were tested preretreat, 1 month and 6 months postretreat. Retreat participants demonstrated increased spirituality. PMID:20421752

  3. New Insights into Antarctic Ice-Sheet Retreat During the Last Sea-Level Rise

    NASA Astrophysics Data System (ADS)

    Weber, M. E.; Kuhn, G.; Clark, P. U.; Sprenk, D.

    2010-12-01

    Reconstruction of the last global sea level rise faces uncertainties because only a few robust results are available for Antarctic ice sheets. Modeling studies reconstruct a late ice-sheet retreat starting around 12 ka BP and ending around 7 ka BP with a large impact of an unstable West Antarctic Ice Sheet (WAIS) and a small impact of a stable East Antarctic Ice Sheet (EAIS). However, two regions in the Atlantic sector of the Southern Ocean provide evidence that Antarctica responded much earlier and possibly provided a significant contribution to the last sea-level rise. On the continental slope of the southeastern Weddell Sea, seven Polarstern cores preserved varved sediment during the Last Glacial Maximum (LGM), indicative for intense, seasonally variable bottom-water production, presumably caused by brine injection in polynias and shelf-ice plowing in front of the ice shelf, which had advanced toward the shelf edge. The following postglacial bioturbated mud favors at least partially open surface water and occasionally intensified iceberg calving. The termination of varvation marked the retreat of the EAIS from the shelf edge around 19 ka BP. The timing coincides with Meltwater Pulse 19 ka from the Northern Hemisphere (NH) and with the initiation of the temperature increase over East Antarctica. After a short ice re-advance, a second retreat occurred around 16 ka - also a time of enhanced global sea-level rise and a period when glaciers rapidly retreated in Patagonia. Sediments from the central Scotia Sea are located in the prolongation of the “iceberg alley”, where icebergs exit the Weddell Sea to the north. Accordingly, this is an excellent location to trace ice-sheet dynamics. Sites MD07-3134 and MD07-3133 document four phases of enhanced iceberg activity as indicated by the amount of small ice-rafted debris (IRD) at 19.5, 16.5,14.5, and 12 ka. The first two are most likely related to the two ice-sheet retreat signals documented by the Weddell Sea sites

  4. Longitudinal laser ion acceleration in low density targets: experimental optimization on the Titan laser facility and numerical investigation of the ultra-high intensity limit

    NASA Astrophysics Data System (ADS)

    d'Humières, E.; Chen, S.; Lobet, Mathieu; Sciscio, M.; Antici, Patrizio; Bailly-Grandvaux, Mathieu; Gangolf, Thomas; Revet, Guilhem; Santos, Joao J.; Schroer, Anna-Marie; Willi, O.; Tikhonchuk, Vladimir T.; Pepin, Henri; Fuchs, Julien

    2015-05-01

    Recent theoretical and experimental studies suggest the possibility of enhancing the efficiency and ease of laser acceleration of protons and ions using underdense or near critical plasmas through electrostatic shocks. Very promising results were recently obtained in this regime. In these experiments, a first ns pulse was focused on a thin target to explode it and a second laser with a high intensity was focused on the exploded foil. The delay between two lasers allowed to control the density gradient seen by the second laser pulse. The transition between various laser ion acceleration regimes depending on the density gradient length was studied. With a laser energy of a few Joules, protons with energies close to the energies of TNSA accelerated protons were obtained for various exploded foils configurations. In the high energy regime (~180 J), protons with energies significantly higher than the ones of TNSA accelerated protons were obtained when exploding the foil while keeping a good beam quality. These results demonstrate that low-density targets are promising candidates for an efficient proton source that can be optimized by choosing appropriate plasma conditions. New experiments were also performed in this regime with gas jets. Scaling shock acceleration in the low density regime to ultra high intensities is a challenge as radiation losses and electron positron pair production change the optimization of the shock process. Using large-scale Particle-In-Cell simulations, the transition to this regime in which intense beams of relativistic ions can be produced is investigated.

  5. The Comparative Efficacy of Different Files in The Removal of Different Sealers in Simulated Root Canal Retreatment- An In-vitro Study

    PubMed Central

    Kanaparthy, Aruna

    2016-01-01

    Introduction Root canal treatment enjoys a high success rate all over the world and has saved billions of teeth from extraction. However, there are instances of failure, the main causes being insufficient cleaning and inadequate obturation. In such cases the most conservative treatment option would be non-surgical retreatment. It requires regaining access to the entire root canal system through removal of the original root canal filling thus permitting further cleaning and re- obturation. Removal of gutta-percha and sealer becomes a critical step to gain access to the root canal system, remove necrotic tissue debris, bacteria and infected dentin. Aim To compare and evaluate the efficacy of manual hand Hedstrom files and two rotary retreatment file systems ProTaper Universal retreatment files and MtwoR (retreatment) files in the removal of root canal filling material during root canal retreatment and the influence of the type of sealers zinc oxide eugenol and AH plus on the presence of remaining debris in the reinstrumented canals in the apical, middle and coronal third. Materials and Methods Sixty single rooted human premolar teeth were divided into 3 Groups of 20 teeth each Group I (20 Teeth): prepared using hand K Files, Group II (20 Teeth): prepared using ProTaper rotary system and Group III (20 Teeth): prepared using Mtwo rotary system. In Groups- IA, IIA, IIIA: (10 teeth each) Obturation was done using Zinc Oxide Eugenol sealer and gutta percha. In Groups- IB, IIB, IIIB: (10 teeth each) obturation was done with AH Plus sealer and gutta percha. All the teeth were subjected to retreatment. Groups IA and IB with Hedstrom files, Groups IIA and IIB with ProTaper retreatment files and for Groups IIIA and IIIB with Mtwo retreatment Files. The roots were longitudinally split and were observed under a stereomicroscope for remaining amount of filling material on the canal walls. Statistical analysis was done using One–way ANOVA (Analysis of variance) test and Tukey

  6. Pathological organizations and psychic retreats in eating disorders.

    PubMed

    Kadish, Yael Adira

    2012-04-01

    A set of characteristic symptoms allow for the relatively straightforward diagnosis of eating disorders. Simultaneously and paradoxically, underlying the eating disorders are a wide variety of personality organizations/disorders, stretching from the neurotic to the borderline and narcissistic, and even to conditions approaching psychosis. This paper will argue that the inherent commonalities can be ascribed to pathological organizations of a similar nature and quality, operational across the spectrum of eating disorders and functioning in a particular, sadomasochistic way. The typical forms that eating disorders take are based on the specific ways that food and the body are used, that is, symptom manifestation. These distinctive symptom manifestations appear to be related to Steiner's (1982, 1993) notion of a psychic retreat. Pathological organizations and psychic retreats are latent until called upon either sporadically or continuously. When activated, these defensive structures operate like a complex psychic skeleton around which the unique psychodynamics of each patient become rearranged and thereby transformed. PMID:22489814

  7. Biological Response to Recent Pacific Arctic Sea Ice Retreats

    NASA Astrophysics Data System (ADS)

    Grebmeier, Jacqueline M.; Moore, Sue E.; Overland, James E.; Frey, Karen E.; Gradinger, Rolf

    2010-05-01

    Although recent major changes in the physical domain of the Arctic region, such as extreme retreats of summer sea ice since 2007, are well documented, large uncertainties remain regarding responses in the biological domain. In the Pacific Arctic north of Bering Strait, reduction in sea ice extent has been seasonally asymmetric, with minimal changes until the end of June and delayed sea ice formation in late autumn. The effect of extreme ice retreats and seasonal asymmetry in sea ice loss on primary production is uncertain, with no clear shift over time (2003-2008) in satellite-derived chlorophyll concentrations. However, clear changes have occurred during summer in species ranges for zooplankton, bottom-dwelling organisms (benthos), and fish, as well as through the loss of sea ice as habitat and platform for marine mammals.

  8. Aegean tectonics: Strain localisation, slab tearing and trench retreat

    NASA Astrophysics Data System (ADS)

    Jolivet, Laurent; Faccenna, Claudio; Huet, Benjamin; Labrousse, Loïc; Le Pourhiet, Laetitia; Lacombe, Olivier; Lecomte, Emmanuel; Burov, Evguenii; Denèle, Yoann; Brun, Jean-Pierre; Philippon, Mélody; Paul, Anne; Salaün, Gwenaëlle; Karabulut, Hayrullah; Piromallo, Claudia; Monié, Patrick; Gueydan, Frédéric; Okay, Aral I.; Oberhänsli, Roland; Pourteau, Amaury; Augier, Romain; Gadenne, Leslie; Driussi, Olivier

    2013-06-01

    We review the geodynamic evolution of the Aegean-Anatolia region and discuss strain localisation there over geological times. From Late Eocene to Present, crustal deformation in the Aegean backarc has localised progressively during slab retreat. Extension started with the formation of the Rhodope Metamorphic Core Complex (Eocene) and migrated to the Cyclades and the northern Menderes Massif (Oligocene and Miocene), accommodated by crustal-scale detachments and a first series of core complexes (MCCs). Extension then localised in Western Turkey, the Corinth Rift and the external Hellenic arc after Messinian times, while the North Anatolian Fault penetrated the Aegean Sea. Through time the direction and style of extension have not changed significantly except in terms of localisation. The contributions of progressive slab retreat and tearing, basal drag, extrusion tectonics and tectonic inheritance are discussed and we favour a model (1) where slab retreat is the main driving engine, (2) successive slab tearing episodes are the main causes of this stepwise strain localisation and (3) the inherited heterogeneity of the crust is a major factor for localising detachments. The continental crust has an inherited strong heterogeneity and crustal-scale contacts such as major thrust planes act as weak zones or as zones of contrast of resistance and viscosity that can localise later deformation. The dynamics of slabs at depth and the asthenospheric flow due to slab retreat also have influence strain localisation in the upper plate. Successive slab ruptures from the Middle Miocene to the Late Miocene have isolated a narrow strip of lithosphere, still attached to the African lithosphere below Crete. The formation of the North Anatolian Fault is partly a consequence of this evolution. The extrusion of Anatolia and the Aegean extension are partly driven from below (asthenospheric flow) and from above (extrusion of a lid of rigid crust).

  9. Climate Change and Glacier Retreat: Scientific Fact and Artistic Opportunity

    NASA Astrophysics Data System (ADS)

    Fagre, D. B.

    2008-12-01

    Mountain glaciers continue to retreat rapidly over most of the globe. In North America, at Glacier National Park, Montana, recent research results from Sperry Glacier (2005-2007) indicate negative mass balances are now 3-4 times greater than in the 1950s. A geospatial model of glacier retreat in the Blackfoot-Jackson basin suggested all glaciers would be gone by 2030 but has proved too conservative. Accelerated glacier shrinkage since the model was developed has mirrored an increase in actual annual temperature that is almost twice the rate used in the model. The glaciers in Glacier National Park are likely to be gone well before 2030. A variety of media, curricula, and educational strategies have been employed to communicate the disappearance of the glaciers as a consequence of global warming. These have included everything from print media and television coverage to podcasts and wayside exhibits along roads in the park. However, a new thrust is to partner with artists to communicate climate change issues to new audiences and through different channels. A scientist-artist retreat was convened to explore the tension between keeping artistic products grounded in factually-based reality while providing for freedom to express artistic creativity. Individual artists and scientists have worked to create aesthetic and emotional images, using painting, poetry, music and photography, to convey core messages from research on mountain ecosystems. Finally, a traveling art exhibit was developed to highlight the photography that systematically documents glacier change through time. The aim was to select photographs that provide the most compelling visual experience for an art-oriented viewer and also accurately reflect the research on glacier retreat. The exhibit opens on January 11, 2009

  10. Scientific Investigators Retreat Brings Like Minds Together | Poster

    Cancer.gov

    Scientists throughout NCI gathered at the 2016 Intramural Scientific Investigators Retreat on Jan. 12, at the Ronald Reagan Building and International Trade Center, to discuss the results of their research with fellow investigators. Several researchers who have made significant advances toward the goal of eliminating the threat of cancer spoke to a packed auditorium of like-minded experts. Speaker topics included the role genetics play in the risk of breast cancer, using fiberglass to...

  11. Retreatment Predictions in Odontology by means of CBR Systems.

    PubMed

    Campo, Livia; Aliaga, Ignacio J; De Paz, Juan F; García, Alvaro Enrique; Bajo, Javier; Villarubia, Gabriel; Corchado, Juan M

    2016-01-01

    The field of odontology requires an appropriate adjustment of treatments according to the circumstances of each patient. A follow-up treatment for a patient experiencing problems from a previous procedure such as endodontic therapy, for example, may not necessarily preclude the possibility of extraction. It is therefore necessary to investigate new solutions aimed at analyzing data and, with regard to the given values, determine whether dental retreatment is required. In this work, we present a decision support system which applies the case-based reasoning (CBR) paradigm, specifically designed to predict the practicality of performing or not performing a retreatment. Thus, the system uses previous experiences to provide new predictions, which is completely innovative in the field of odontology. The proposed prediction technique includes an innovative combination of methods that minimizes false negatives to the greatest possible extent. False negatives refer to a prediction favoring a retreatment when in fact it would be ineffective. The combination of methods is performed by applying an optimization problem to reduce incorrect classifications and takes into account different parameters, such as precision, recall, and statistical probabilities. The proposed system was tested in a real environment and the results obtained are promising. PMID:26884749

  12. Retreatment Predictions in Odontology by means of CBR Systems

    PubMed Central

    Campo, Livia; Aliaga, Ignacio J.; García, Alvaro Enrique; Villarubia, Gabriel; Corchado, Juan M.

    2016-01-01

    The field of odontology requires an appropriate adjustment of treatments according to the circumstances of each patient. A follow-up treatment for a patient experiencing problems from a previous procedure such as endodontic therapy, for example, may not necessarily preclude the possibility of extraction. It is therefore necessary to investigate new solutions aimed at analyzing data and, with regard to the given values, determine whether dental retreatment is required. In this work, we present a decision support system which applies the case-based reasoning (CBR) paradigm, specifically designed to predict the practicality of performing or not performing a retreatment. Thus, the system uses previous experiences to provide new predictions, which is completely innovative in the field of odontology. The proposed prediction technique includes an innovative combination of methods that minimizes false negatives to the greatest possible extent. False negatives refer to a prediction favoring a retreatment when in fact it would be ineffective. The combination of methods is performed by applying an optimization problem to reduce incorrect classifications and takes into account different parameters, such as precision, recall, and statistical probabilities. The proposed system was tested in a real environment and the results obtained are promising. PMID:26884749

  13. 3-Year follow-up after Lasik: assessing the risk factors for retreatment.

    PubMed

    Valdez-García, Jorge E; Hernandez-Camarena, Julio C; Martínez-Muñoz, Rosa

    2016-02-01

    The purpose of this study was to evaluate the correlation of important risk factors for LASIK retreatment and the retreatment rate. A retrospective cohort study was conducted. Records of patients who underwent LASIK between January 2011 and January 2012 at the Zambrano-Hellion Medical Center, Tec de Monterrey (México), and posteriorly underwent LASIK retreatment were identified and risk factors to receive retreatment were assessed using relative risk. Main outcomes were retreatment rate, risk factors for retreatment, and uncorrected distance visual acuity (UDVA). 482 eyes from 241 patients were available for a 36-month follow-up analysis. 68.5 % had primary myopic LASIK; 37 % were ≤ 2 diopters (D), 52 % were > 2 and < 6 D, and 11 % were ≥ 6 D of myopia. 31.5 % of the eyes had hyperopic LASIK. Retreatment was performed in 6.85 % eyes. Myopia > 6 D (RR 4.13), hyperopic refraction (RR 3.18), and age > 40 (RR 3.07) were the most important risk factors for retreatment (P = 0.004, P = 0.007, P = 0.006, respectively). UDVA was ≥ 20/40 in 92.1 % and ≥ 20/20 in 81.6 % of the retreated eyes and 82 % of the eyes within ± 0.50 D of target refraction. Increasing degrees of myopia, followed by hyperopic refraction, and age were the most important associated factors to retreatment. LASIK retreatment was safe and effective. PMID:25985886

  14. Sediment connectivity evolution on an alpine catchment undergoing glacier retreat

    NASA Astrophysics Data System (ADS)

    Goldin, Beatrice; Rudaz, Benjamin; Bardou, Eric

    2014-05-01

    Climate changes can result in a wide range of variations of natural environment including retreating glaciers. Melting from glaciers will have a significant impact on the sediment transport characteristics of glacierized alpine catchments that can affect downstream channel network. Sediment connectivity assessment, i.e. the degree of connections that controls sediment fluxes between different segments of a landscape, can be useful in order to address management activity on sediment fluxes changes of alpine streams. Through the spatial characterization of the connectivity patterns of a catchment and its potential evolution it is possible to both define sediment transport pathways and estimate different contributions of the sub-catchment as sediment sources. In this study, a topography based index (Cavalli et al., 2013) has been applied to assess spatial sediment connectivity in the Navisence catchment (35 km2), an alpine basin located in the southern Walliser Alps (Switzerland) characterized by a complex glacier system with well-developed lateral moraines on glacier margins already crossed by several lateral channels. Glacier retreat of the main glacial edifice will provide a new connectivity pattern. At present the glacier disconnects lateral slopes from the main talweg: it is expected that its retreat will experience an increased connectivity. In order to study this evolution, two high resolution (2 m) digital terrain models (DTMs) describing respectively the terrain before and after glacier retreat have been analyzed. The current DTM was obtained from high resolution photogrammetry (2 m resolution). The future DTM was derived from application of the sloping local base level (SLBL) routine (Jaboyedoff et al., 2004) on the current glacier system, allowing to remove the ice body by reconstituting a U-shaped polynomial bedrock surface. From this new surface a coherent river network was drawn and slight random noise was added. Finally the river network was burned into

  15. On the Lateral Retreat of Salt Marshes: Field Monitoring in the Venice Lagoon (Italy)

    NASA Astrophysics Data System (ADS)

    Solari, L.; Bendoni, M.; Mel, R.; Oumeraci, H.; Francalanci, S.; Lanzoni, S.

    2014-12-01

    Salt marshes are geomorphic structures located in ecotone environments such as lagoon and estuaries, providing lot of ecosystem services to local population. In the last decades they are disappearing due to several factors such as sea level rise, subsidence and edge erosion due to surface waves. The latter is likely the chief mechanism modeling marsh boundaries and leading to the loss of wide marsh areas. In the case of the Venice Lagoon, from the beginning of the last century, the whole salt marsh surface has more than halved and trends indicate that the salt marshes might completely disappear over the next 50 years. Here, we present a field monitoring activity that we are currently carrying out on a retreating salt marsh located in the north part of the Lagoon of Venice (Italy). The marsh is subject to North-East (Bora) wind. Marsh area loss during the last decades has been documented through the comparison of georeferenced aerial photographs showing a retreat rate of the order of 1 m/year. Field measurements started by the end of November 2013 and consist of: salt marsh bank geometry at different cross-sections and wave climate in the lagoon about 30 m in front of the salt marsh. Erosion data are obtained by means of erosion pins located horizontally on the marsh scarp; at higher banks (about 0.9 m), two pins are located along the same vertical direction, for lower banks (about 0.4m), only one pin is employed. Significant wave height has been measured during three storm surges by means of pressure transducers (Pts). The measured wave climate in front of the bank was then put into relationship with the offshore wave climate estimated using wind data (intensity and direction) and bathymetric data. Wind intensity and direction is measured hourly by several measurement stations located in the Lagoon of Venice. In this way, it is possible to extrapolate wave climate hourly at the monitored marsh and calculate the wave power that acted on the bank in a given time

  16. On the Lateral Retreat of Salt Marshes: Field Monitoring in the Venice Lagoon (Italy)

    NASA Astrophysics Data System (ADS)

    Solari, L.

    2015-12-01

    Salt marshes are geomorphic structures located in ecotone environments such as lagoon and estuaries, providing lot of ecosystem services to local population. In the last decades they are disappearing due to several factors such as sea level rise, subsidence and edge erosion due to surface waves. The latter is likely the chief mechanism modeling marsh boundaries and leading to the loss of wide marsh areas. In the case of the Venice Lagoon, from the beginning of the last century, the whole salt marsh surface has more than halved and trends indicate that the salt marshes might completely disappear over the next 50 years. Here, we present a field monitoring activity on a retreating salt marsh located in the north part of the Lagoon of Venice (Italy). The marsh is subject to North-East (Bora) wind. Marsh area loss during the last decades has been documented through the comparison of georeferenced aerial photographs showing a retreat rate of the order of 1 m/year. Field measurements started by the end of November 2013 and consist of: salt marsh bank geometry at different cross-sections and wave climate in the lagoon about 30 m in front of the salt marsh. Erosion data are obtained by means of erosion pins located horizontally on the marsh scarp; at higher banks (about 0.9 m), two pins are located along the same vertical direction, for lower banks (about 0.4 m), only one pin is employed. Significant wave height has been measured during three storm surges by means of pressure transducers. The measured wave climate in front of the bank was then put into relationship with the offshore wave climate estimated using wind data (intensity and direction) and bathymetric data. Wind intensity and direction is measured hourly by several measurement stations located in the Lagoon of Venice. In this way, it is possible to extrapolate wave climate hourly at the monitored marsh and calculate the wave power that acted on the bank in a given time interval. Field survey revealed that the

  17. Idiopathic Polydactylous Longitudinal Erythronychia

    PubMed Central

    2011-01-01

    Objective: To describe the clinical features of idiopathic polydactylous longitudinal erythronychia. Introduction: Longitudinal erythronychia presents as a linear red band on the nail plate. Idiopathic polydactylous longitudinal erythronychia is a rarely described manifestation of longitudinal erythronychia in which one or more linear red bands present on the nails of multiple digits without any associated subungual malignant tumor, dermatological condition, or systemic disease. Methods: As part of a total body skin examination, the fingernails and toenails were evaluated for linear red bands. Results: One or more asymptomatic linear red bands (longitudinal erythronychia) was observed on multiple digits of the hands in one percent (3 men of 134 men and 112 women) of patients examined during a period of 75 days. The author also noted similar changes of his own nails. Between 3 to 10 digits were affected. Multiple linear red bands per nail were usually narrow (less than 1mm wide), whereas a single band on a nail often ranged from 4 to 6mm wide. The intensity of an individual wider linear red band was position-dependent in three individuals in whom the distal portion appeared less prominent when the affected digit was held upward above the level of the patient's heart—pseudolongitudinal erythronychia. Other nail changes in these patients included distal subungual hyperkeratosis, fissuring at the free end of the nail, leukonychia, red lunula, and splinter hemorrhages. Discussion: Idiopathic polydactylous longitudinal erythronychia is a benign, usually asymptomatic, condition of undetermined etiology characterized by one or more linear red bands originating at the proximal nail fold or distal lunula and extending to the free edge of the nail. It appears to be more prevalent in men over 50 years of age and its incidence was noted to be one percent of adults attending a dermatology clinic. Patients are either unaware of the nail changes or seek medical attention because

  18. Low retreat rate sea cliff monitoring by photogrammetric methods

    NASA Astrophysics Data System (ADS)

    Marques, F.; Redweik, P.; Matildes, R.; Santos, L.

    2009-04-01

    Sea cliff evolution is dominated by the occurrence of mass movements of different types and sizes, being a considerable source of natural hazard in coastal areas. Hazard assessment requires the use of substantially complete inventories of cliff failures occurred in the past, which are usually produced by multi-temporal aerial photo based studies, where photogrammetric methods still combine the advantages of high accuracy and the possibility of monitoring periods of time in excess of half a century. However, the study of low retreat rate cliffs still involves problems, because parts of the cliff top contour remain unchanged during the monitoring period and retreat is restricted to the places where cliff failures have occurred. This situation creates problems related with the inherent difficulties of a multi-temporal processing of aerial photos (different flight directions and scales, insufficient ground control for older photos and poor radiometric quality) and requires the use of refined photogrammetric approaches to prevent the generation of false mass movements, which cannot be included in the inventories. Because cliff retreat is discontinuous in space and time, better sampling of the process requires the widening of the monitoring time window, by use of older aerial photos, which involve further problems as unavailable camera calibration and photo distortions. To address these problems, the sea cliffs of Burgau-Lagos coast (Southwest Algarve, Portugal) were studied using digital photogrammetry methods, which involved several aerotriangulation steps, generation of pseudo-camera data for the older aerial photos, stereo plotting of the cliff top, ridges and toe and automatic generation of digital terrain models. Inconsistencies in the results were solved by systematic stereo photo interpretation, supported by oblique aerial photos. This study enabled the detection and characterization of 137 cliff failures that occurred between 1947 and 2007 along the 13 km long

  19. Salt Marshes as Monitors of Late Holocene Outlet Glacier Retreat

    NASA Astrophysics Data System (ADS)

    Wake, L. M.; Woodroffe, S.; Long, A. J.; Milne, G. A.

    2014-12-01

    New proxy sea-level records extracted from salt marshes in the vicinity of Jakobshavn Isbrae (Pakitsoq; 69.51°N, 50.74°W) and at previous sites in central western Greenland (Sisimiut; 66.47°N, 53.61°W and Aasiaat; 68.69°N, 52.88°W) are analyzed with respect to their ability to act as proximal tide gauges detecting mass balance changes in nearby outlet glaciers associated with the transition from the Little Ice Age ("LIA", 1400-1850AD) to the Industrial Period (>1850AD). Data at Pakitsoq demonstrate that sea-level rose at a rate of 3.5 ±1.7 mm/yr prior to 1850AD and slowed to 0.3 ±0.6mm/yr thereafter, producing a slowdown in sea level of 3.2 ± 1.8 mm/yr. A similar slowdown, occurring at 1600AD, is observed at Aasiaat and Sisimiut. We interpret these observed changes using a glacial isostatic adjustment model of sea-level change truncated at degree and order 4096, with an aim to determine if the sea-level data can be used to place constraints on changes in Jakobshavn Isbrae and/or Kangiata Nunaata Sermia (Nuuk fjord) during this period. Modelled sea level at Pakitsoq is insensitive to the location of thickening (thinning) associated with grounding line advance (retreat) and the rate of advance and retreat but is sensitive to the change point in time between periods of growth associated with LIA expansion (sea level rise) and the onset of 19th century recession (sea level fall) of Jakobshavn Isbrae. We conclude that the change in sea-level rate observed at Pakitsoq circa 1850AD marks the onset of post LIA retreat of this outlet glacier. Conversely, the modelled sea-level response to the retreat of Kangiata Nunaata Sermia from its LIA maximum at ca. 1761AD is below the detection threshold of the salt marsh record at Sisimiut.

  20. Retreatability of Root Canals Obturated Using Gutta-Percha with Bioceramic, MTA and Resin-Based Sealers

    PubMed Central

    Uzunoglu, Emel; Yilmaz, Zeliha; Sungur, Derya Deniz; Altundasar, Emre

    2015-01-01

    Introduction: The aim of this study was to evaluate the retreatability of root canals obturated with gutta-percha (GP) and three different endodontic sealers [iRoot SP (bioceramic sealer), MTA Fillapex (MTA-based sealer) and AH-26 (epoxy resin-based sealer)] using the ProTaper Universal Retreatment (PTR) system. Methods and Materials: Forty extracted single-rooted human teeth were prepared with universal ProTaper files up to F4 (40/0.06). Specimens were randomly divided into four groups according to obturation technique/material: single-cone GP/AH-26, lateral compaction of GP/AH-26, single-cone GP/iRoot SP, and single-cone GP/MTA Fillapex. Root fillings were removed with PTR. The time taken to reach the working-length (TWL) was recorded. Roots were longitudinally sectioned and each half was evaluated using a stereomicroscope. Three observers scored each third of all specimen. Obtained data were analyzed using the Kruskal-Wallis, Mann-Whitney U, Welch and Games-Howell tests. The level of significance was set at 0.05. Results: In single-cone GP/MTA Fillapex group the TWL was significantly shorter. The remnant of filling material in the apical and middle thirds of groups was similar and higher than the coronal thirds. Conclusion: None of the tested sealers were completely removed from the root canal system. PMID:25834591

  1. Comparison of ProTaper and Mtwo retreatment systems in the removal of resin-based root canal obturation materials during retreatment.

    PubMed

    Iriboz, Emre; Sazak Öveçoğlu, Hesna

    2014-04-01

    To evaluate the effectiveness of the ProTaper and Mtwo retreatment systems for removal of resin-based obturation techniques during retreatment. A total of 160 maxillary anterior teeth were enlarged to size 30 using ProTaper and Mtwo rotary instruments. Teeth were randomly divided into eight groups. Resilon + Epiphany, gutta-percha + Epiphany, gutta-percha + AH Plus and gutta-percha + Kerr Pulp Canal Sealer (PCS) combinations were used for obturation. ProTaper and Mtwo retreatment files were used for removal of root canal treatments. After clearing the roots, the teeth were split vertically into halves, and the cleanliness of the canal walls was determined by scanning electron microscopy. Specimens obturated with gutta-percha and Kerr PCS displayed significantly more remnant obturation material than did specimens filled with resin-based obturation materials. Teeth prepared with Mtwo instruments contained significantly more remnant filling material than did teeth prepared with ProTaper. ProTaper files were significantly faster than Mtwo instruments in terms of the mean time of retreatment and time required to reach working length. The Resilon + Epiphany and AH Plus + gutta-percha obturation materials were removed more easily than were the Epiphany + gutta-percha and Kerr PCS + gutta-percha obturation materials. Although ProTaper retreatment files worked faster than did Mtwo retreatment files in terms of removing root canal obturation materials, both retreatment systems are effective, reliable and fast. PMID:24697958

  2. The 22nd annual prostate cancer foundation scientific retreat report.

    PubMed

    Miyahira, Andrea K; Simons, Jonathan W; Soule, Howard R

    2016-09-01

    The 22nd Annual Prostate Cancer Foundation (PCF) Scientific Retreat was convened in Washington, D.C. from October 8 to 10, 2015. This event is the foremost scientific conference in the world focusing on basic, translational, and clinical prostate cancer research with the highest potential for accelerating the understanding of prostate cancer biology and improving the lives and outcomes of prostate cancer patients. Topics highlighted during the 2015 Retreat included: (i) new strategies and treatments for localized high-risk, hormone-naïve, oligometastatic, castrate-resistant, and treatment-refractory prostate cancer settings; (ii) the biology and genomics of tumor heterogeneity and tumor evolution; (iii) new understandings on the mechanisms and targeting of oncogenic drivers of prostate cancer; (iv) bioengineering of novel therapies and drug delivery methods; (v) innovative approaches to tumor immunotherapy; (vi) emerging molecular imaging technologies with improved sensitivity and specificity; and (vii) advancements in prognostic and predictive biomarkers and precision medicine strategies. Prostate 76:1037-1052, 2016. © 2016 Wiley Periodicals, Inc. PMID:27272144

  3. Insights into lateral marsh retreat mechanism through localized field measurements

    NASA Astrophysics Data System (ADS)

    Bendoni, M.; Mel, R.; Solari, L.; Lanzoni, S.; Francalanci, S.; Oumeraci, H.

    2016-02-01

    Deterioration of salt marshes may be due to several factors related to increased anthropic pressure, sea level rise, and erosive processes. While salt marshes can reach equilibrium in the vertical direction, adapting to sea level rise, they are inherently unstable in the horizontal direction. Marsh boundaries are characterized by scarps with bare sediment below the vegetated surface layer that can be easily removed by wave-induced erosion. In this work, we explore the different mechanisms involved in the erosion of marsh borders through the interpretation of field data. The analysis is based on a systematic field monitoring of a salt marsh in the Venice Lagoon subject to lateral erosion. Measurements included horizontal retreat of the scarp at various locations and wave height in front of the marsh during three storm surges. Continuous erosion and mass failures alternated during the observed period, leading to an average retreat up to 80 cm/yr. The data, collected roughly every month for 1.5 year, indicate that the linear relation that links the observed erosion rate to the impinging wave power exhibits a larger slope than that already estimated in literature on the basis of long-term surveys. Moreover, an increase in the gradient of erodibility is detected along the marsh scarp, due to the combined action of soil strengthening by vegetation on the marsh surface and the impact of wave breaking at the bank toe, which promote cantilever failures and increase the lateral erosion rate.

  4. Evaluation of three different rotary systems during endodontic retreatment - Analysis by scanning electron microscopy

    PubMed Central

    Vidal, Flávia-Teixeira; Nunes, Eduardo; Horta, Martinho-Campolina-Rebello; Freitas, Maria-Rita-Lopes-da Silva

    2016-01-01

    Background Endodontic therapy is considered a series of important and interdependent steps, and failure of any of these steps may compromise the treatment outcome. This study aimed to evaluate the effectiveness of three different rotary systems in removing obturation materials during endodontic retreatment using scanning electron microscopy (SEM) analysis. Material and Methods Thirty-six endodontically treated teeth were selected and divided into 3 groups of 10 and 1 control group with 6 dental elements. The groups were divided according to the rotary system used for removing gutta-percha, as follows: G1: ProTaper system; G2: K3 system; G3: Mtwo system; and G4: Control group. Thereafter, the roots were split and the sections were observed under SEM, for analysis and counting of clear dentinal tubules, creating the variable “degree of dentinal tubule patency” (0: intensely clear; 1: moderately clear; 2: slightly clear; 3: completely blocked). The data were subjected to the Friedman and Kruskal-Wallis statistical tests. Results No differences were observed in the “degree of dentinal tubule patency” neither between the root thirds (to each evaluated group) nor between the groups (to each evaluated third). Nevertheless, when the three root thirds were grouped (providing evaluation of all root extension), the “degree of dentinal tubule patency” was lower in G1 than in G3 (p<0.05), but showed no differences neither between G1 and G2 nor G2 and G3. Conclusions No technique was able to completely remove the canal obturation material, despite G1 having shown better results, although without significant difference to G2 Key words:Scanning electron microscopy, NiTi, retreatment. PMID:27034750

  5. Ecological Succession, Land use Changes and Soil Organic C Stock in a Lake Retreat Area (Main Ethiopian Rift Valley)

    NASA Astrophysics Data System (ADS)

    Nyssen, J.; Temesgen, H.; Lemenih, M.; Zenebe, A.; Kindu, M.; Haile, M.

    2007-12-01

    In the Main Ethiopian Rift Valley, ecological succession is related to continuous lake retreat (Nyssen et al., 2004). Human activities, through their impact on land use and cover, affect this ecological succession. Through a remote sensing study, we extricated ecological succession and human activity as causative factors for land use and cover changes (LUCC) and explored which impact this has on soil organic C (SOC) stock in lake retreat areas. Remote sensing data used include a Landsat MSS from 1973, a Landsat TM from 1986 and a Landsat ETM+ from 2000. A conventional type of classification was used whereby supervised classification of the 2000 image was supplemented by unsupervised classification of the older datasets. Due to decreased rainfall and water abstraction for intense irrigated agriculture and floriculture in its catchment, Lake Abijata lost 46 % of its area between 2000 and 2006. On the emerged lands, a good ecological succession was observed between 1973 and 1986, with clear evidence for: emerged land -> grassland -> Acacia bushes -> open woodland. Between 1986 and 2000, LUCC tendencies were totally reversed and woody vegetation decreased strongly, indicating increased human impact (Habtamu et al., 2007). Based on an analysis of the Landsat imagery, coupled with soil and land use studies, determinants for SOC stock were found. Firstly, SOC stock significantly differs between cultivated land and grazing land (3301 and 2626 g m-2) on the one hand, and woodland (4594 g m-2) on the other. The strongest explanation of SOC stock is related to the duration of emergence and hence of pedogenesis. Its proxy, elevation, explains much of the variability of SOC (R2 = 0.48). Using a multiple regression model involving elevation and IR reflectance, the SOC stock in the study area could be assessed at 2196 (+ - 1517) g m-2 SOC in 2000, against 3222 (+ - 1639) g m-2 in 1973 (Nyssen et al., 2007), which is related to the post-1986 reversing of ecological succession in

  6. Probabilistic estimation of dun retreate on the Gold Coast, Australia

    USGS Publications Warehouse

    Palmsten, Margaret L.; Splinter, Kristen D.; Plant, Nathaniel G.; Stockdon, Hilary F.

    2014-01-01

    Sand dunes are an important natural buffer between storm impacts and development backing the beach on the Gold Coast of Queensland, Australia. The ability to forecast dune erosion at a prediction horizon of days to a week would allow efficient and timely response to dune erosion in this highly populated area. Towards this goal, we modified an existing probabilistic dune erosion model for use on the Gold Coast. The original model was trained using observations of dune response from Hurricane Ivan on Santa Rosa Island, Florida, USA (Plant and Stockdon 2012. Probabilistic prediction of barrier-island response to hurricanes, Journal of Geophysical Research, 117(F3), F03015). The model relates dune position change to pre-storm dune elevations, dune widths, and beach widths, along with storm surge and run-up using a Bayesian network. The Bayesian approach captures the uncertainty of inputs and predictions through the conditional probabilities between variables. Three versions of the barrier island response Bayesian network were tested for use on the Gold Coast. One network has the same structure as the original and was trained with the Santa Rosa Island data. The second network has a modified design and was trained using only pre- and post-storm data from 1988-2009 for the Gold Coast. The third version of the network has the same design as the second version of the network and was trained with the combined data from the Gold Coast and Santa Rosa Island. The two networks modified for use on the Gold Coast hindcast dune retreat with equal accuracy. Both networks explained 60% of the observed dune retreat variance, which is comparable to the skill observed by Plant and Stockdon (2012) in the initial Bayesian network application at Santa Rosa Island. The new networks improved predictions relative to application of the original network on the Gold Coast. Dune width was the most important morphologic variable in hindcasting dune retreat, while hydrodynamic variables, surge and

  7. Testing geographical and climatic controls on glacier retreat

    NASA Astrophysics Data System (ADS)

    Freudiger, Daphné; Stahl, Kerstin; Weiler, Markus

    2015-04-01

    Glacier melt provides an important part of the summer discharge in many mountainous basins. The understanding of the processes behind the glacier mass losses and glacier retreats observed during the last century is therefore relevant for a sustainable management of the water resources and reliable models for the prediction of future changes. The changes in glacier area of 49 sub-basins of the Rhine River in the Alps were analyzed for the time period 1900-2010 by comparing the glacier areas of Siegfried maps for the years 1900 and 1940 with satellite derived glacier areas for the years 1973, 2003 and 2010. The aim was to empirically investigate the controls of glacier retreat and its regional differences. All glaciers in the glacierized basins retreated over the last 110 years with some variations in the sub-periods. However, the relative changes in glacier area compared to 1900 differed for every sub-basin and some glaciers decreased much faster than others. These observed differences were related to a variety of different potential controls derived from different sources, including mean annual solar radiation on the glacier surface, average slope, mean glacier elevation, initial glacier area, average precipitation (summer and winter), and the precipitation catchment area of the glacier. We fitted a generalized linear model (GLM) and selected predictors that were significant to assess the individual effects of the potential controls. The fitted model explains more than 60% of the observed variance of the relative change in glacier area with the initial area alone only explaining a small proportion. Some interesting patterns emerge with higher average elevation resulting in higher area changes, but steeper slopes or solar radiation resulting in lower relative glacier area changes. Further controls that will be tested include snow transport by wind or avalanches as they play an important role for the glacier mass balance and potentially reduce the changes in glacier

  8. Writing Retreat Increases Productivity And Community For Women Geoscientists

    NASA Astrophysics Data System (ADS)

    O'Connell, S.; Holmes, M.

    2011-12-01

    Five, weeklong geoscientist writing retreats have been completed with an NSF ADANCE PAID grant. During the five nights and four and a half days, eight to twenty-four academics have gathered in a rural setting outside of Boston to get to focus on writing papers and proposals while getting to know each other. Participants range in age and experience from graduate students to emeritus professors. Over twenty papers and proposals acknowledge their production, in part to this writing retreat. Impact extends beyond papers as informal mentoring and discussions at meals and in the evenings centers on succeeding in academia. Research and teaching are foremost in the conversation. Post-docs learn strategies for applying for jobs and grants, and senior professors discuss strategies for working with academic administrations, running departments and mentoring students. They also learn new technologies and perspectives from younger participants. Particularly helpful are discussions on work-life balance. Networking opportunities extend beyond the retreat as participants join each other at their home institutions to give seminars, develop research projects and mentor each other's students. All weeks follow the same format. Participants arrive Sunday and meet during an evening welcome reception. Monday is devoted to writing. Tuesday a writing coach is available. In the morning, using examples from the scientific literature, she discusses strategies and techniques for writing clearly at a group session. During the afternoon, participants work with the coach individually or in small groups to improve their own writing projects. Wednesday evening a skill session is offered on a topic of interest. These have included undergraduate research, NSF funding, productive techniques for dealing with conflict, and generational characteristics and attitudes, which can hamper communication. A Thursday evening wrap-up session prepares participants for Friday's departure. We believe that this model

  9. The Writing Retreat: A High-Yield Clinical Faculty Development Opportunity in Academic Writing

    PubMed Central

    Cable, Christian T.; Boyer, Debra; Colbert, Colleen Y.; Boyer, Edward W.

    2013-01-01

    Background The need for consistent academic productivity challenges junior clinician-scholars, who often lack the aptitude to ensure efficient production of manuscripts. Intervention To solve this problem, an academic division of a major medical center developed an off-site writing retreat. The purpose of the retreat was not to teach writing skills, but to offer senior mentor assistance with a focus on the elements of manuscript writing. Methods The retreat paired senior faculty members with junior staff. Senior faculty identified manuscript topics and provided real-time writing and editing supervision. Team-building exercises, midcourse corrections, and debriefing interviews were built into the retreat. The number of manuscripts and grant proposals generated during the 2008–2011 retreats was recorded, and the program was evaluated by using unstructured debriefing interviews. Results An average of 6 to 7 faculty members and fellows participated in each retreat. During the past 4 years, participants produced an average of 3 grant proposals and 7 manuscripts per retreat. After the writing retreat, each fellow and junior faculty member produced an average of 4 scholarly products per year, compared to fewer than 2 for prior years' retreats. Participant feedback indicated the success of the retreat resulted from protected time, direct mentorship by the scholars involved, and pairing of authors, which allows for rapid production of manuscripts and accelerated the editing process. More than 80% of mentors returned each year to participate. Conclusions The writing retreat is a feasible, effective strategy to increase scholarship among faculty, acceptable to mentees and mentors, and sustainable over time. PMID:24404277

  10. Cleaning and retreatment protocol for a debonded ceramic restoration

    PubMed Central

    Alonso-Pérez-Barquero, Jorge; Bruguera-Álvarez, August; Agustín-Panadero, Rubén; Fons-Font, Antonio

    2015-01-01

    Objectives: The aim of this article is to propose a resin cement cleaning protocol for use before recementing a debonded restoration. Study Design: Ceramic samples were fabricated from IPS d.sign® and IPS e.max Press® and were treated with hydrofluoric acid etching (HF), or HF+silane (S), or HF+S+adhesive or HF+S+A+resin cement. All samples were placed in a furnace at 650º for one minute in order to attempt to pyrolyze the composite. Each step was examined under scanning electron microscopy (SEM). Results: When the cleaning protocol had been performed, it left a clean and retentive surface. Conclusions: If the restoration is placed in a furnace at 650º for one minute, the composite cement will burn or pyrolyze and disappear, allowing conventional retreatment of the ceramic before rebonding. Key words:Ceramic, debond, surface treatment. PMID:25810843

  11. WHO in retreat: is it losing its influence?

    PubMed Central

    Godlee, F.

    1994-01-01

    WHO says it has three main functions: to set normative standards; to provide technical advice and assistance on medical matters; and to advocate changes in health policy. During its 46 year history the first two functions have been a constant and uncontroversial backbone through which WHO has earned its reputation for scientific excellence. The third function, advocacy, came to the fore with the launch of Health for All in 1977, after which WHO took a key role in influencing international health policy. WHO's friends and critics alike now say that the organisation is losing its influence and retreating into its technical and biomedical shell. This article maps the changes in WHO's approach over the past 46 years and considers whether fears about its loss of influence are justified. Images p1492-a p1492-b p1493-a p1494-a FIG 1 PMID:7804058

  12. Holocene Glacial Retreat at Walgreen Coast, West Antarctica

    NASA Astrophysics Data System (ADS)

    Lindow, J.; Johnson, J.; Castex, M.; Wittmann, H.; Smith, J.; Lisker, F.; Gohl, K.; Spiegel, C.

    2012-12-01

    The Walgreen Coast of West Antarctica represents one of the most rapidly changing sectors of the West Antarctic Ice Sheet (WAIS). With the fastest ice streams in the whole Antarctic, the WAIS is characterised by rapid thinning and grounding line retreat. Airborne and satellite-based short-term observations show a doubling of the negative net mass balance between 1996-2006 (Rignot et al., 2008). Furthermore, because the WAIS is largely grounded below sea level, continued inland thinning and grounding line retreat could result in rapid ice sheet collapse, which would raise global sea level by between 3-5 m. However, due to remoteness and challenging accessibility, onshore data is limited to a few isolated nunataks making it difficult to assess the long-term evolution of the glacial dynamics along Walgreen Coast. To address this we present new data from two key areas of the Walgreen Coast; the Kohler Range and the Pine Island Bay. Our 10Be surface exposure ages from erratic boulders in the Kohler Range are the first and reveal that this area became ice-free between 8.3 and 12.3 ka. This implies a long-term thinning rate of 3.3 cm/yr and agrees with similar data published from glaciers eastward. Our ages are also consistent with recent deglaciation models which suggest strong thinning after 15 ka and off-shore sediments shows a concurrent lateral ice-shelf front retreat. Our results suggest an ice-cover at least 300 m thicker in the Kohler Range during the early Holocene and that subsequent average thinning occurred on rates one order of magnitude slower than recent satellite measurements show. This implies that the recent trend in ice-sheet thinning results from a recent dynamic changes rather than a response to long-term thinning. To further constrain the lateral deglaciation history along the eastern Walgreen Coast, namely the Pine Island Glacier, we collected additional samples from a chain of islands, located flow-parallel and downstream of the ice-shelf front. We

  13. Reducing roof fall accidents on retreat mining sections

    SciTech Connect

    Mark, C.; Zelanko, J.C.

    2005-12-15

    Pillar recovery continues to be one of the most hazardous activities in underground mining. Global stability, achieved through proper pillar design, is a necessary prerequisite for safe pillar recovery. Local stability means preventing roof falls in the working area. It is achieved by minimizing the 'risk factors' described in this paper. Roof Control Plans developed at each underground coal mine often address both engineering parameters and human behavior issues. These plans are essential to all mining activities, but nowhere are they more important than in pillar recovery. Pillaring leaves little tolerance for error, and mistakes can be deadly. Roof Control Plans must be carefully drawn up to address site-specific conditions, and then carefully implemented and followed. Miners and foremen involved in pillar extraction should be trained to know and understand the plan prior to beginning retreat mining. More details can be found at www.cdc.gov/niosh/mining/pubs/pdfs/rtrog.pdf. 3 figs.

  14. North Atlantic warming and the retreat of Greenland's outlet glaciers.

    PubMed

    Straneo, Fiammetta; Heimbach, Patrick

    2013-12-01

    Mass loss from the Greenland ice sheet quadrupled over the past two decades, contributing a quarter of the observed global sea-level rise. Increased submarine melting is thought to have triggered the retreat of Greenland's outlet glaciers, which is partly responsible for the ice loss. However, the chain of events and physical processes remain elusive. Recent evidence suggests that an anomalous inflow of subtropical waters driven by atmospheric changes, multidecadal natural ocean variability and a long-term increase in the North Atlantic's upper ocean heat content since the 1950s all contributed to a warming of the subpolar North Atlantic. This led, in conjunction with increased runoff, to enhanced submarine glacier melting. Future climate projections raise the potential for continued increases in warming and ice-mass loss, with implications for sea level and climate. PMID:24305146

  15. Long-term shoreline retreat rates on Whidbey Island, Washington, USA

    NASA Astrophysics Data System (ADS)

    Rogers, Heather E.; Swanson, Terry W.; Stone, John O.

    2012-09-01

    Long-term retreat rates of Puget Sound's unconsolidated sediment shorelines have been difficult to quantify, and little systematic research has been completed to constrain retreat in this area. We put forward a new application of cosmogenic 10Be exposure dating to assess long-term shoreline retreat on Whidbey Island, WA by dating lag boulders exposed on the shore platform as the shoreline erodes. Production of 10Be in shoreline boulders is modulated by both tidal submergence and topographic shielding from the retreating bluff. By modeling the combined effect of these variables on 10Be production, the timing of exposure can be determined and used to calculate long-term (103-104 yr) bluff retreat rates. In rare cases, retreat rates are underestimated due to inherited 10Be. Within the study area, average retreat rates ranged between 0 and 8 cm yr- 1. Our results demonstrate the utility of cosmogenic nuclides for determining long-term shoreline retreat rates in areas with thick sediment cover, where large numbers of samples can be collected, and where the pre-depositional history of the boulders is uncomplicated.

  16. Teacher Retreating: The Little Known Behavior That Impacts Teaching and Learning

    ERIC Educational Resources Information Center

    Ratcliff, Nancy J.; Carroll, Kimberly L.; Hunt, Gilbert H.

    2014-01-01

    This paper discusses findings from four years of observational research examining classroom climate. Specifically, findings that focused on one powerful teacher behavior (teacher retreating) were examined. These data indicated that teacher retreating was negatively correlated to the amount of instructional interaction occurring between students…

  17. Evaluation of a gully headcut retreat model using multitemporal aerial photographs and digital elevation models

    NASA Astrophysics Data System (ADS)

    Campo-Bescós, M. A.; Flores-Cervantes, J. H.; Bras, R. L.; Casalí, J.; Giráldez, J. V.

    2013-12-01

    large fraction of soil erosion in temperate climate systems proceeds from gully headcut growth processes. Nevertheless, headcut retreat is not well understood. Few erosion models include gully headcut growth processes, and none of the existing headcut retreat models have been tested against long-term retreat rate estimates. In this work the headcut retreat resulting from plunge pool erosion in the Channel Hillslope Integrated Landscape Development (CHILD) model is calibrated and compared to long-term evolution measurements of six gullies at the Bardenas Reales, northeast Spain. The headcut retreat module of CHILD was calibrated by adjusting the shape factor parameter to fit the observed retreat and volumetric soil loss of one gully during a 36 year period, using reported and collected field data to parameterize the rest of the model. To test the calibrated model, estimates by CHILD were compared to observations of headcut retreat from five other neighboring gullies. The differences in volumetric soil loss rates between the simulations and observations were less than 0.05 m3 yr-1, on average, with standard deviations smaller than 0.35 m3 yr-1. These results are the first evaluation of the headcut retreat module implemented in CHILD with a field data set. These results also show the usefulness of the model as a tool for simulating long-term volumetric gully evolution due to plunge pool erosion.

  18. The Rhetoric of Strategic Retreat: Carter and the Panama Canal Debate.

    ERIC Educational Resources Information Center

    Sudol, Ronald A.

    1979-01-01

    Discusses President Carter's televised address on the Panama Canal Treaties in terms of five "topoi" for a rhetoric of retreat: timeliness, urgency, value, advantage, and shrewdness. Compares his failure to employ the commonsense arguments that a policy of retreat requires in the televised speech with his more successful impromptu speeches. (JMF)

  19. Ipilimumab retreatment in patients with pretreated advanced melanoma: the expanded access programme in Italy

    PubMed Central

    Chiarion-Sileni, V; Pigozzo, J; Ascierto, P A; Simeone, E; Maio, M; Calabrò, L; Marchetti, P; De Galitiis, F; Testori, A; Ferrucci, P F; Queirolo, P; Spagnolo, F; Quaglino, P; Carnevale Schianca, F; Mandalà, M; Di Guardo, L; Del Vecchio, M

    2014-01-01

    Background: Retreatment with ipilimumab has been shown to re-establish disease control in some patients with disease progression. Here, we report the efficacy and safety of retreatment with ipilimumab 3 mg kg−1 among patients participating in an expanded access programme in Italy. Methods: Patients who achieved disease control during induction therapy were retreated with ipilimumab upon progression (3 mg kg−1 every 3 weeks for up to four doses), providing they had not experienced toxicity that precluded further dosing. Tumour assessments were conducted after retreatment, and patients were monitored throughout for adverse events. Results: Of 855 patients treated with ipilimumab, 51 were retreated upon disease progression. Of these, 28 (55%) regained disease control upon retreatment and 42% were alive 2 years after the first induction dose of ipilimumab; median overall survival was 21 months. Eleven patients (22%) had a treatment-related adverse event of any grade during retreatment. These were generally mild-to-moderate and resolved within a median of 4 days. No new types of toxicity were reported. Conclusions: For patients who meet predefined criteria, retreatment with ipilimumab is generally well tolerated and can translate into clinical benefit. This strategy should be compared with other therapeutic options in randomised controlled trials. PMID:24619072

  20. Impact of different file systems on the amount of apically extruded debris during endodontic retreatment

    PubMed Central

    Uzunoglu, Emel; Turker, Sevinc Aktemur

    2016-01-01

    Objective: The goal of present study was to determine the effect of different nickel–titanium file systems on the amount of apically extruded debris during endodontic retreatment: D-RaCe retreatment systems, EdgeFile XR retreatment rotary files, and Reciproc R40. Materials and Methods: Thirty-six single-rooted prepared mandibular premolar teeth were filled with Gutta-percha and AH Plus sealer. The teeth were then randomly assigned into three groups (n = 12) for retreatment. The endodontic retreatment was performed as follows: D-RaCe, EdgeFile XR, Reciproc 40. Debris extruded apically during the retreatment was collected into preweighed Eppendorf tubes. An incubator was used to store tubes at 70° C for 5 days. The initial weight was subtracted from final weight of the Eppendorf tubes to calculate the weight of the dry extruded debris for each group. The data obtained were evaluated using Welch analysis of variance and Games-Howell post-hoc tests (P < 0.05). Results: All files resulted in apical extrusion of debris. Reciproc caused significantly less debris extrusion compared to D-RaCe and EdgeFile XR (P < 0.05). Conclusions: The findings revealed that during endodontic retreatment, number, and taper of files might have an influence on the amount of apically extruded debris during endodontic retreatment. PMID:27095898

  1. Regional and global forcing of glacier retreat during the last deglaciation

    NASA Astrophysics Data System (ADS)

    Shakun, Jeremy D.; Clark, Peter U.; He, Feng; Lifton, Nathaniel A.; Liu, Zhengyu; Otto-Bliesner, Bette L.

    2015-08-01

    The ongoing retreat of glaciers globally is one of the clearest manifestations of recent global warming associated with rising greenhouse gas concentrations. By comparison, the importance of greenhouse gases in driving glacier retreat during the most recent deglaciation, the last major interval of global warming, is unclear due to uncertainties in the timing of retreat around the world. Here we use recently improved cosmogenic-nuclide production-rate calibrations to recalculate the ages of 1,116 glacial boulders from 195 moraines that provide broad coverage of retreat in mid-to-low-latitude regions. This revised history, in conjunction with transient climate model simulations, suggests that while several regional-scale forcings, including insolation, ice sheets and ocean circulation, modulated glacier responses regionally, they are unable to account for global-scale retreat, which is most likely related to increasing greenhouse gas concentrations.

  2. Regional and global forcing of glacier retreat during the last deglaciation

    PubMed Central

    Shakun, Jeremy D.; Clark, Peter U.; He, Feng; Lifton, Nathaniel A.; Liu, Zhengyu; Otto-Bliesner, Bette L.

    2015-01-01

    The ongoing retreat of glaciers globally is one of the clearest manifestations of recent global warming associated with rising greenhouse gas concentrations. By comparison, the importance of greenhouse gases in driving glacier retreat during the most recent deglaciation, the last major interval of global warming, is unclear due to uncertainties in the timing of retreat around the world. Here we use recently improved cosmogenic-nuclide production-rate calibrations to recalculate the ages of 1,116 glacial boulders from 195 moraines that provide broad coverage of retreat in mid-to-low-latitude regions. This revised history, in conjunction with transient climate model simulations, suggests that while several regional-scale forcings, including insolation, ice sheets and ocean circulation, modulated glacier responses regionally, they are unable to account for global-scale retreat, which is most likely related to increasing greenhouse gas concentrations. PMID:26293133

  3. Regional and global forcing of glacier retreat during the last deglaciation.

    PubMed

    Shakun, Jeremy D; Clark, Peter U; He, Feng; Lifton, Nathaniel A; Liu, Zhengyu; Otto-Bliesner, Bette L

    2015-01-01

    The ongoing retreat of glaciers globally is one of the clearest manifestations of recent global warming associated with rising greenhouse gas concentrations. By comparison, the importance of greenhouse gases in driving glacier retreat during the most recent deglaciation, the last major interval of global warming, is unclear due to uncertainties in the timing of retreat around the world. Here we use recently improved cosmogenic-nuclide production-rate calibrations to recalculate the ages of 1,116 glacial boulders from 195 moraines that provide broad coverage of retreat in mid-to-low-latitude regions. This revised history, in conjunction with transient climate model simulations, suggests that while several regional-scale forcings, including insolation, ice sheets and ocean circulation, modulated glacier responses regionally, they are unable to account for global-scale retreat, which is most likely related to increasing greenhouse gas concentrations. PMID:26293133

  4. Mentored residential writing retreats: a leadership strategy to develop skills and generate outcomes in writing for publication.

    PubMed

    Jackson, Debra

    2009-01-01

    There is an increasing expectation that academic and clinical nurses will contribute to disciplinary and professional discourses through scholarly writing. However, the difficulties and challenges associated with writing for publication mean that many papers will never be written. This current paper describes an innovative approach developed to support skill development and outcomes in writing for publication. Intensive residential writing retreats informed by the principles of servant leadership and incorporating strategies such as mentoring and peer learning were conducted in 2005 and 2007. Positive outcomes and benefits included publications submitted to peer-reviewed journals, as well as positive effects on collegial relationships, and team building. Novice writers benefited from intensive and sustained support and coaching by experienced writers. Organisational benefits included increased participation by staff and research higher degree students in publication activities, enhanced collegial relationships and opportunities for senior established writers to work with inexperienced writers. PMID:18692282

  5. Rapid last-deglacial thinning and retreat of the marine-terminating southwestern Greenland ice sheet

    NASA Astrophysics Data System (ADS)

    Winsor, Kelsey; Carlson, Anders E.; Caffee, Marc W.; Rood, Dylan H.

    2015-09-01

    Marine-terminating outlet glaciers are a major source of modern ice loss from the Greenland Ice Sheet (GrIS), but their role in GrIS retreat during the last deglaciation is not well constrained. Here, we develop deglacial outlet glacier retreat chronologies for four regions in southwest and south Greenland to improve understanding of spatial variations in centennial- to millennial-scale ice loss under a warming climate. We calculate 10Be surface exposure ages of boulders located in fjords near the towns of Qaqortoq, Paamiut, Nuuk, and Sisimiut. Our northernmost study site, Sisimiut, deglaciated earliest at ∼18 ka to ∼15 ka with an average thinning rate of 0.1-0.3 m yr-1. Inland retreat from Sisimiut to the modern ice margin took ∼7 ka at an average retreat rate of 15-20 m yr-1. A 10Be-dated moraine ∼25 km from the modern GrIS margin deposited at ∼8 ka suggests a possible ice-margin still-stand, but this does not change overall retreat rates. After retreat from the small coastal Sisimiut fjords, the GrIS margin was mainly land-terminating in this region. In contrast, earliest exposure occurred at ∼12 ka near Qaqortoq, and 11-10 ka near Nuuk and Paamiut, with ice thinning at rates of 0.2-0.3 m yr-1 to instantaneous within measurement uncertainty. Ice retreat inland through the extensive Nuuk, Paamiut, and Qaqortoq fjord systems to near modern ice margins occurred in <1 ka, resulting in minimum retreat rates of 25-65 m yr-1 and maximum retreat rates of ∼95 m yr-1 to instantaneous within the uncertainty of our measurements. This rapid thinning and retreat of marine-terminating southwest GrIS margins is contemporaneous with an incursion of relatively warm ocean waters into the Labrador Sea and toward the southwest Greenland coast, suggesting that a warming ocean may have contributed to the more rapid retreat of marine GrIS termini in the Nuuk, Paamiut, and Qaqortoq fjord systems relative to the slower ice retreat inland from Sisimiut. Our results highlight

  6. EVALUATION RETREAT: A SENSIBLE METHOD FOR PROGRAM’S ASSESSMENT

    PubMed Central

    Rios, R.; Estapé, E.; Díaz, C.; Segarra, B.; Martin, M. San

    2015-01-01

    Purpose The University of Puerto Rico (UPR), Medical Sciences Campus (MSC) post-doctoral Master of Science in Clinical and Translational Research (MSc) program aims to train Hispanic post-doctoral candidates to advance their careers and become successful clinical and translational researchers geared to help eliminate health disparities. Its curriculum highlights the use of technology and online resources to maximize time use of time and efforts. As part of the assessment efforts, the program’s Evaluation Committee leads an annual activity, Evaluation Retreat (ER), to evaluate the program’s curriculum, research component, and mentoring experience according to Scholars’ perspective. Results are used by the Program Executive committee for further planning and improvement. This analysis presents the most relevant results from these activities. Design Methods Data collection (from last 5 years), include quantitative (online surveys) and qualitative approaches (a group meeting with Scholars.) Questionnaires request Scholars to rate specific features of the program’s research component, mentoring experience and curriculum. It also includes questions about the program in general (major strengths and challenges, and recommendations for improvement. During the group meeting, Scholars discuss these results and present consensus in a plenary session. Quantitative data are managed and analyzed using the statistical software SPSS. Qualitative data are examined using content analysis. Results Scholars identified as program’s strengths the networking opportunities (local and with U.S. experts), the diversity of peers and faculty, the faculty support, the technical and audiovisual support, the physical facilities and resources, the guest speakers and consultants, and the quality of the curriculum. Challenges vary as cohorts change, but time limitations and the need for technical/statistical support are always highlighted. Recommendations for improvement emphasize the need

  7. Bathymetric Controls On Observed Tidewater Glacier Retreat In Northwest Greenland

    NASA Astrophysics Data System (ADS)

    Porter, D. F.; Tinto, K. J.; Boghosian, A.; Cochran, J. R.; Bell, R. E.

    2013-12-01

    Although many of the largest glaciers in Greenland are losing mass, the large variability in observed mass wastage of the remaining glaciers clouds interpretation of the proposed external forcings, such as warming of the ocean or atmosphere. Some glaciers are accelerating and thinning while other nearby glaciers advance and gain mass. Recent efforts suggest that increased ocean temperatures may be responsible for the observed glacial retreat in Greenland and Antarctica through increased basal melting beneath floating ice tongues and vertical ice faces of tidewater glaciers. Basal melting may contribute significantly to calving and thinning, and to an eventual speeding up of the glacier, resulting in thinning further inland. Knowledge of fjord geometry is crucial for ice-ocean interaction because the availability of ocean heat to the ice will be restricted by narrow sills and shallow grounding lines. We investigate whether the variability in observed changes among Greenland glaciers can be partially explained by variation in fjord geometry. Some features of a fjord that could influence the ice-ocean system include the depth of the grounding line, the presence of sills, sloping bed, and the water cavity shape beneath floating ice. New estimates of fjord bathymetries in northwest Greenland, using airborne gravimetry measurements from NASA Operation IceBridge flights, are compared to estimates of ice acceleration and mass wastage of neighboring glaciers. We investigate the correlation between fjord geometry features and several glacier parameters, such as surface velocity and elevation changes. We determine that the geometry of glacial fjords play a large role in determining the stability of outlet glaciers. Deep sills and deep terminus grounding lines will allow greater interaction with the deep and warm Atlantic water off the shelf break. For two neighboring glaciers in northwest Greenland, we find that the glacier with a deeper grounding line, and presumably in

  8. Holocene - historical - decadal - annual retreat rates along the eastern Mediterranean coastal cliff of Israel

    NASA Astrophysics Data System (ADS)

    Katz, Oded; Mushkin, Amit; Kober, Florian; Porat, Naomi

    2013-04-01

    The Israeli coastal cliff extends about 50 km along the eastern Mediterranean and is comprised of late Quaternary eolianites and paleosols that reach heights of up to 50 meters above current sea-level. Variable cliff-top inland retreat rates of up to a few tens of centimeters per year have been previously measured along the cliff line usually by comparing aerial photos from the last decades. Commonly, these locally constrained retreat rates have been: 1) extrapolated as representative of the entire cliff length, and 2) adopted by hazard-mitigation and planning authorities. Here, we re-evaluate the current understanding of retreat patterns and rates along this cliff line using a suite of ground-based LiDAR observations, airborne LiDAR, aerial photography, archeology and numerical (OSL) age determination of older coastal cliff locations. Annual retreat rates and patterns were constrained using repeat high-resolution ground based LiDAR. In places, storm induced landward cliff retreat reached 7 m/yr, which is comparable to the total retreat previously documented along this coastal stretch during the past 60 years. Yet, spatially - cliff-retreat activity per given year was documented along less than 5% of the entire cliff length. Decadal-scale retreat rates along the entire coastal cliff were mapped by comparing the cliff-top location in aerial photos from 1945 and 2004. These revealed cliff-top retreat rates of less than 0.1 m/yr along 58 % of the cliff length and >0.4 m/yr retreat rates along only several % of the cliff length. Extended stretches of the cliff line (~50%) did not experience detectable retreat in the past 60 years and thus appear to have remained stable during this time period. Local retreat rates at centennial to millennial time scales were constrained at a cliff-top archeological site where a Crusader castle appears to have lost <20 m of its outer walls as well as at a natural site where the past locations of the cliff are marked by multiple cliff

  9. No improvement in serological response among serofast latent patients retreated with benzathine penicillin.

    PubMed

    Ren, Rong-Xin; Wang, Lin-Na; Zheng, He-Yi; Li, Jun

    2016-01-01

    Persistent non-treponemal titres after treatment are common among patients with latent syphilis. Although retreatment is often done in clinical practice, optimal management remains uncertain due to the paucity of data regarding serological response to retreatment and long-term outcomes. We compared the serological responses of serofast latent syphilis patients retreated with 7.2 million units of benzathine penicillin with the responses of patients who did not receive retreatment (control group). We retrospectively analysed the serological response to therapy following retreatment of 35 serofast latent syphilis patients at 12 months with benzathine penicillin 2.4 million units weekly for 3 weeks. In all, 74.3% (26/35) of the cases with latent syphilis who failed to achieve serological cure at 12 months after initial therapy achieved serological cure after retreatment and after an additional 12 months of follow-up. However, statistically similar serological cure rate was observed in 80.0% (28/35) of the control group (p > .05). Our findings illustrate no improvement in serological response among serofast latent patients retreated with three doses of benzathine penicillin. PMID:25691394

  10. Glacier retreat and projected river regime changes in the hydrologically highly-coupled Virkisjökull catchment, Iceland

    NASA Astrophysics Data System (ADS)

    Flett, Verity; Kirkbride, Martin; Black, Andrew; Everest, Jez; MacDonald, Alan

    2016-04-01

    Virkisjökull, an outlet glacier of the Oræfajökull icecap in SE Iceland, currently has 60% glacier cover, though this is reducing due to glacier retreat. Intensive monitoring over the last 4 years includes measurement of measuring ice ablation, proglacial discharge, dye-tracing of flow pathways, and deployment of three automatic weather stations at altitudes up to 880 m. These data calibrate a distributed hydrological model (WaSIM) to project potential river regime during stages of glacier retreat. Results show: (1) glacier hypsometry sensitises the catchment to a disproportionately rapid increase in runoff as the snowline rises onto a gentle ice cap resulting in in a potential annual increase in river discharge of up to 37% (2) a dominantly channelized glacial drainage system in all seasons with a rapid runoff response to melt: englacial flow of 0.58 m s-1 is comparable to the proglacial river velocity; and (3) longer-term, reduced glacier cover and snow storage will lead to a discharge regime dominated by short-term precipitation events in all seasons, and a reduced influence of the seasonal meltwater discharge peak. The study demonstrates the importance of glacier hypsometry above the present ELA as an influence on catchment hydrological response to potential climate warming.

  11. The 20th Annual Prostate Cancer Foundation Scientific Retreat report.

    PubMed

    Miyahira, Andrea K; Simons, Jonathan W; Soule, Howard R

    2014-06-01

    The 20th Annual Prostate Cancer Foundation (PCF) Scientific Retreat was held from October 24 to 26, 2013, in National Harbor, Maryland. This event is held annually for the purpose of convening a diverse group of leading experimental and clinical researchers from academia, industry, and government to present and discuss critical and emerging topics relevant to prostate cancer (PCa) biology, and the diagnosis, prognosis, and treatment of PCa patients, with a focus on results that will lend to treatments for the most life-threatening stages of this disease. The themes that were highlighted at this year's event included: (i) mechanisms of PCa initiation and progression: cellular origins, neurons and neuroendocrine PCa, long non-coding RNAs, epigenetics, tumor cell metabolism, tumor-immune interactions, and novel molecular mechanisms; (ii) advancements in precision medicine strategies and predictive biomarkers of progression, survival, and drug sensitivities, including the analysis of circulating tumor cells and cell-free tumor DNA-new methods for liquid biopsies; (iii) new treatments including epigenomic therapy and immunotherapy, discovery of new treatment targets, and defining and targeting mechanisms of resistance to androgen-axis therapeutics; and (iv) new experimental and clinical epidemiology methods and techniques, including PCa population studies using patho-epidemiology. PMID:24719035

  12. Extinction and ecological retreat in a community of primates

    PubMed Central

    Crowley, Brooke E.; Godfrey, Laurie R.; Guilderson, Thomas P.; Zermeño, Paula; Koch, Paul L.; Dominy, Nathaniel J.

    2012-01-01

    The lemurs of Madagascar represent a prodigious adaptive radiation. At least 17 species ranging from 11 to 160 kg have become extinct during the past 2000 years. The effect of this loss on contemporary lemurs is unknown. The concept of competitive release favours the expansion of living species into vacant niches. Alternatively, factors that triggered the extinction of some species could have also reduced community-wide niche breadth. Here, we use radiocarbon and stable isotope data to examine temporal shifts in the niches of extant lemur species following the extinction of eight large-bodied species. We focus on southwestern Madagascar and report profound isotopic shifts, both from the time when now-extinct lemurs abounded and from the time immediately following their decline to the present. Unexpectedly, the past environments exploited by lemurs were drier than the protected (albeit often degraded) riparian habitats assumed to be ideal for lemurs today. Neither competitive release nor niche contraction can explain these observed trends. We develop an alternative hypothesis: ecological retreat, which suggests that factors surrounding extinction may force surviving species into marginal or previously unfilled niches. PMID:22628463

  13. In Review (Geology): Alpine Landscape Evolution Dominated by Cirque Retreat

    NASA Technical Reports Server (NTRS)

    Oskin, Michael; Burbank, Doug

    2005-01-01

    Despite the abundance in alpine terrain of glacially dissected landscapes, the magnitude and geometry of glacial erosion can rarely be defined. In the eastern Kyrgyz Range, a widespread unconformity exhumed as a geomorphic surface provides a regional datum with which to calibrate erosion. As tectonically driven surface uplift has progressively pushed this surface into the zone of ice accumulation, glacial erosion has overprinted the landscape. With as little as 500 m of incision into rocks underlying the unconformity, distinctive glacial valleys display their deepest incision adjacent to cirque headwalls. The expansion of north-facing glacial cirques at the expense of south-facing valleys has driven the drainage divide southwards at rates up to 2 to 3 times the rate of valley incision. Existing ice-flux-based glacial erosion rules incompletely model expansion of glacial valleys via cirque retreat into the low-gradient unconformity remnants. Local processes that either directly sap cirque headwalls or inhibit erosion down-glacier appear to control, at least initially, alpine landscape evolution.

  14. Paludification and Forest Retreat in Northern Oceanic Environments

    PubMed Central

    CRAWFORD, R. M. M.; JEFFREE, C. E.; REES, W. G.

    2003-01-01

    Examination of temperature variations over the past century for Europe and the Arctic from northern Norway to Siberia suggests that variations in the North Atlantic Oscillation are associated with an increase in oceanicity in certain maritime regions. A southward depression of the treeline in favour of wet heaths, bogs and wetland tundra communities is also observed in northern oceanic environments. The physiological basis for this change in ecological succession from forest to bog is discussed in relation to the long‐term effects of flooding on tree survival. The heightened values currently detected in the North Atlantic Oscillation Index, together with rising winter temperatures, and increased rainfall in many areas in northern Europe, presents an increasing risk of paludification with adverse consequences for forest regeneration, particularly in areas with oceanic climates. Climatic warming in oceanic areas may increase the area covered by bogs and, contrary to general expectations, lead to a retreat rather than an advance in the northern limit of the boreal forest. High water‐table levels are not automatically detrimental to forest survival as can be seen in swamp, bottomland and mangrove forests. Consequently, the inhibitory effects of flooding on tree survival and regeneration in northern regions should not be uncritically accepted as merely due to high water levels. Evidence is discussed which suggests that physiological and ecological factors may interact to inhibit forest regeneration in habitats where there is a risk of prolonged winter‐flooding combined with warmer winters and cool moist summers. PMID:12509342

  15. Clinical microscopic analysis of ProTaper retreatment system efficacy considering root canal thirds using three endodontic sealers.

    PubMed

    Só, Marcus Vinícius Reis; De Figueiredo, Jose Antônio Poli; Freitas Fachin, Elaine Vianna; Húngaro Duarte, Marco Antônio; Pereira, Jefferson Ricardo; Kuga, Milton Carlos; Da Rosa, Ricardo Abreu

    2012-09-01

    To evaluate the efficacy of ProTaper Universal rotary retreatment system and the influence of sealer type on the presence of filling debris in the reinstrumented canals viewed in an operative clinical microscope. Forty-five palatal root canals of first molars were filled with gutta-percha and one of the following sealers: G1, EndoFill; G2, AH Plus; G3, Sealapex. The canals were then reinstrumented with ProTaper Universal rotary system. Roots were longitudinally sectioned and examined under an operative clinical microscope (10×), and the amount of filling debris on canal walls was analyzed using the AutoCAD 2004 software. A single operator used a specific software tool to outline the canal area and the filling debris area in each third (cervical, middle, and apical), as well as the total canal area. Data were analyzed by Kruskal-Wallis test and Tukey test at P < 0.05. Sealapex demonstrated significant differences in the average of filling debris area/canal among the 3 thirds. This group revealed that apical third showed more debris than the both cervical and middle third (P < 0.0001). Endofill presented significantly more filling debris than Sealapex in the cervical third (P < 0.05). In the middle (P = 0.12) and apical third (P = 0.10), there were no differences amongst groups. Debris was left in all canal thirds, regardless of the retreatment technique. The greatest differences between techniques and sealers were found in the cervical third. PMID:22496039

  16. Operation restoration: couples reunification retreats for veterans of operations enduring and iraqi freedom.

    PubMed

    Davis, Louanne W; Paul, Robin; Tarr, David; Eicher, Amanda C; Allinger, Jessica; Knock, Heidi

    2012-11-01

    Couples interventions are promising approaches to help veterans successfully reintegrate into civilian life and recover from combat-related trauma. However, few programs are available to address these needs. This article describes a weekend retreat program we developed called Operation Restoration, which focuses on strengthening the relationships of Operation Enduring Freedom (OEF) and Operation Iraqi Freedom (OIF) veterans and their partners. We also report results from program evaluations completed by participants of the initial two retreats, aimed at further developing and refining Operation Restoration. The program evaluations explored participants' perceptions of the retreat, including benefits gained, suggestions for improvement, and mental health treatment interests. Information gathered from 43 couples suggests that such retreats may be a useful approach for strengthening the intimate relationships of OEF/OIF veterans and gives direction for future programs. PMID:23066828

  17. Four-decade record of pervasive grounding line retreat along the Bellingshausen margin of West Antarctica

    NASA Astrophysics Data System (ADS)

    Christie, Frazer D. W.; Bingham, Robert G.; Gourmelen, Noel; Tett, Simon F. B.; Muto, Atsuhiro

    2016-06-01

    Changes to the grounding line, where grounded ice starts to float, can be used as a remotely sensed measure of ice-sheet susceptibility to ocean-forced dynamic thinning. Constraining this susceptibility is vital for predicting Antarctica's contribution to rising sea levels. We use Landsat imagery to monitor grounding line movement over four decades along the Bellingshausen margin of West Antarctica, an area little monitored despite potential for future ice losses. We show that ~65% of the grounding line retreated from 1990 to 2015, with pervasive and accelerating retreat in regions of fast ice flow and/or thinning ice shelves. Venable Ice Shelf confounds expectations in that, despite extensive thinning, its grounding line has undergone negligible retreat. We present evidence that the ice shelf is currently pinned to a sub-ice topographic high which, if breached, could facilitate ice retreat into a significant inland basin, analogous to nearby Pine Island Glacier.

  18. Glacier retreat in New Zealand during the Younger Dryas stadial.

    PubMed

    Kaplan, Michael R; Schaefer, Joerg M; Denton, George H; Barrell, David J A; Chinn, Trevor J H; Putnam, Aaron E; Andersen, Bjørn G; Finkel, Robert C; Schwartz, Roseanne; Doughty, Alice M

    2010-09-01

    Millennial-scale cold reversals in the high latitudes of both hemispheres interrupted the last transition from full glacial to interglacial climate conditions. The presence of the Younger Dryas stadial (approximately 12.9 to approximately 11.7 kyr ago) is established throughout much of the Northern Hemisphere, but the global timing, nature and extent of the event are not well established. Evidence in mid to low latitudes of the Southern Hemisphere, in particular, has remained perplexing. The debate has in part focused on the behaviour of mountain glaciers in New Zealand, where previous research has found equivocal evidence for the precise timing of increased or reduced ice extent. The interhemispheric behaviour of the climate system during the Younger Dryas thus remains an open question, fundamentally limiting our ability to formulate realistic models of global climate dynamics for this time period. Here we show that New Zealand's glaciers retreated after approximately 13 kyr bp, at the onset of the Younger Dryas, and in general over the subsequent approximately 1.5-kyr period. Our evidence is based on detailed landform mapping, a high-precision (10)Be chronology and reconstruction of former ice extents and snow lines from well-preserved cirque moraines. Our late-glacial glacier chronology matches climatic trends in Antarctica, Southern Ocean behaviour and variations in atmospheric CO(2). The evidence points to a distinct warming of the southern mid-latitude atmosphere during the Younger Dryas and a close coupling between New Zealand's cryosphere and southern high-latitude climate. These findings support the hypothesis that extensive winter sea ice and curtailed meridional ocean overturning in the North Atlantic led to a strong interhemispheric thermal gradient during late-glacial times, in turn leading to increased upwelling and CO(2) release from the Southern Ocean, thereby triggering Southern Hemisphere warming during the northern Younger Dryas. PMID

  19. Why is there no Universal Law for Rock Wall Retreat?

    NASA Astrophysics Data System (ADS)

    Krautblatter, Michael; Moore, Jeffrey

    2016-04-01

    Comparing studies of rock slope erosion and soil slope erosion, we find no governing equation similar to the universal soil loss equation for rock slopes. Rock masses in contact with the atmosphere are affected by a suite of physical, chemical and biological processes which degrade intact rock, creating new fractures and extending existing flaws. Complex feedbacks must be explored between changing slope boundary conditions, stress redistribution and fracturing, and weathering by external mechanisms. Rock slope systems are distinguished from soil slope systems by the fundamental nonlinear properties of rock masses. Rock masses represent discontinuous, inhomogeneous, anisotropic, and nonlinearly elastic materials, and contain a record of millions of years of thermal, hydrological, mechanical and chemical (THMC) processes. The origin and evolution of rock mass strength over time can significantly affect bedrock erodibility and engineering performance, the study of which represents a major chance and challenge for the geoscience community. The imprint of THMC processes on rock properties begins with the geological genesis of rocks; however, a significant degree of material behaviour evolves coincidently with the exhumation and evolution of topography. Thus, fracture generation has been investigated as the result of the environmental stress history in geology and geomorphology, partly modulated by incision and topographic stress evolution. Resultant fracture patterns control the degree of discontinuity heterogeneity, anisotropy, and nonlinear mechanical behaviour over millions of years. Here we discuss important novel conceptual approaches to temporally and spatially decipher nonlinear effects on rock slope erosion including incision-related topographic stresses, rock fatigue, paraglacial and paracratering effects etc. and how they could contribute to a more uniform understanding of rockwall retreat.

  20. Vertical stress redistribution around a retreating longwall face end

    SciTech Connect

    Payne, D.A.; DeMarco, M.

    1995-11-01

    Large excavations, such as longwall panels, result in extensive vertical stress redistribution in the surrounding strata. The large abutment stresses developed may produce damage to pre-existing or planned excavations in the same seam or in seams above and below the workings. Knowledge of the magnitude and location of these stress is therefore important in the design of mine openings; pillar sizes for panel and pillar layouts, roof supports in longwall gateroads and workings over or above pre-existing or planned extracting in adjacent seams. In an attempt to reduce costs, the Cape Breton Development Corporation (CBDC), a Federal Crown Corporation responsible for operating two retreat longwall coal mines, examined the potential for either interpanel barrier pillar width reduction or entire pillar elimination by the adoption of dual life gateroads for the longwall panels. In order to assess the potential for reduced interpanel barrier widths or total elimination, an investigation of the redistribution of vertical stresses around longwall panels in the Sydney Coalfield was established. The study was conducted jointly by the Cape Breton Coal Research Laboratory (CBCRL), of CANMET (a division of Natural Resources Canada) and the Denver Research Center (DRC) of the United States Bureau of Mines. The program included monitoring of vertical stress changes around longwall panels and gateroad behavior in two seams. USBM-style hydraulic borehole pressure cells connected to chart recorders for continuous monitoring were deployed at four sites, two at Lingan Colliery and two at Phalen Colliery. This report describes the investigations conducted at Phalen Colliery. Contoured plots of stress redistribution around two sites are presented.

  1. Antarctic marine ice sheet retreat in the Ross Sea during the early Holocene

    NASA Astrophysics Data System (ADS)

    Mckay, R. M.; Golledge, N.; Naish, T.; Maas, S.; Levy, R. H.; Kuhn, G.; Lee, J. I.; Dunbar, G. B.

    2015-12-01

    Geological constraints on the timing of the retreat of the Last Glacial Maximum (LGM) Antarctic Ice Sheets provide critical insights into the processes controlling marine-based ice sheet stability. The over-deepened, seaward shallowing bathymetry of Antarctica's continental shelves is ideally configured to promote past, and potentially future, marine ice-sheet instability. The retreat history of the LGM ice sheet in the Ross Sea region is primarily constrained by C-14 ages on coastal beach ridges and relict penguin colonies along the Transantarctic Mountain front in the Western Ross Sea. Although these terrestrial sites offer more reliable dates than imprecise C-14 chronologies derived from bulk marine sediments, they may reflect retreat of local piedmont glaciers derived from East Antarctic outlet glaciers rather than representing the timing of retreat of the ice sheet in the central Ross Embayment. We present a sedimentary facies succession and foraminifera-based C-14 chronology from a core collected beneath the Ross Ice Shelf via a hot water drill access hole used for the ANDRILL Coulman High site survey. The site is to the east of Ross Island and distal from the coast, and yields a minimum age for glacial retreat that is approximately 1000 yrs earlier than suggested by coastal records along the nearby Victoria Land coast. We examine the implications of this constraint on the timing of ice sheet retreat in the context of model simulations and new multi-beam bathymetry data acquired in the Western Ross Sea. On the basis of these data we hypothesize that marine-based ice sheet retreat was triggered by oceanic forcings along most of the Pacific Ocean coastline of Antarctica simultaneously, but continued retreat in the Ross Sea occurred primarily as a consequence of marine ice sheet instability.

  2. Retreat space and human visitor density moderate undesirable behavior in petting zoo animals.

    PubMed

    Anderson, Ursula S; Benne, Marcie; Bloomsmith, Mollie A; Maple, Terry L

    2002-01-01

    This study focused on the relationship between nonhuman animal behavior and envi-ronment- specifically, between the undesirable behavior exhibited by domestic pet-ting zoo animals in the presence of humans and the spatial design of the petting zoo environment. A spatial feature of a petting zoo referred to as a retreat space was ma-nipulated so that it affected the animals' opportunity for individual control over inter-action with humans. Three conditions were tested: no retreat space, semi-retreat space, and a full-retreat space. The subjects of this study were 5 African pygmy goats (Capra hircus) and 2 Romanov sheep (Ovis aries). Investigators used a focal sam-pling technique to analyze approximately 27 hr of behavioral data collected. The data were analyzed using multiple linear regression methods. The findings suggest that the full-retreat design beneficially moderated both sheep and goat behavior: Undesirable behaviors were lowest in the full-retreat condition. This study provides information that may improve human-animal interactions in a petting zoo setting and may in-crease animal well-being through exhibit design and management techniques. PMID:12738581

  3. Focusing on Main Street's Problems from Secluded Laboratory Retreats

    ERIC Educational Resources Information Center

    Kushner, Lawrence M.

    1973-01-01

    A report on the National Bureau of Standards is presented. It provides national measurement standards for some 40 physical quantities related through the laws of physics to the basic six - length, time, mass, temperature, electric current, and luminous intensity. (DF)

  4. Small scale tests on the progressive retreat of soil slopes

    NASA Astrophysics Data System (ADS)

    Voulgari, Chrysoula; Utili, Stefano; Castellanza, Riccardo

    2015-04-01

    In this paper, the influence due to the presence of cracks on the morphologic evolution of natural cliffs subject to progressive retreat induced by weathering is investigated through small scale laboratory tests. Weathering turns hard rocks into soft rocks that maintain the structure of the intact rocks, but are characterised by higher void ratios and reduced bond strengths; soft rocks are transformed into granular soils generally called residual soils. A number of landslides develop in slopes due to weathering which results in the progressive retrogression of the slope face and the further degradation within the weathering zone. Cracks, that are widely present, can be a result of weathering and they can cause a significant decrease in their stability, as they provide preferential flow channels which increase the soil permeability and decrease the soil strength. The geological models employed until now are mainly empirical. Several researchers have tried to study the stability of slopes through experimental procedures. Centrifuge modelling is widely used to investigate the failure of slopes. Small scale tests are also an important approach, in order to study the behaviour of a slope under certain conditions, such as the existence of water, as they allow the observation of the infiltration processes, the movement of the weathering front, deformation and failure. However, the deformation response of a slope subject to weathering is not yet thoroughly clarified. In this work, a set of experiments were conducted to investigate weathering induced successive landslides. Weathering was applied to the slope model by wetting the slope crest through a rainfall simulator device. The moisture content of the soil during the tests was monitored by soil moisture sensors that were buried inside the slope model. High resolution cameras were recording the behaviour of the slope model. GeoPIV was used to analyse the frames and obtain the deformations of the slope model during the

  5. Deriving mechanisms and thresholds for cliff retreat in soft-rock cliffs under changing climates: Rapidly retreating cliffs of the Suffolk coast, UK

    NASA Astrophysics Data System (ADS)

    Brooks, S. M.; Spencer, T.; Boreham, S.

    2012-06-01

    Understanding changing thresholds and mechanisms for retreat in soft rock cliffs is important under changing climates. This can be achieved through combining detailed field observation, long-term process and morphological monitoring and numerical modelling. The cliffs of the Suffolk coast, southern North Sea have exhibited long-term (1883-2010) recession rates of 3.5 m a- 1, rising to 4.7 m a- 1 in the period 1993-2010. Annual to biannual ground survey data, and the application of GIS techniques to digitised records of changing shoreline position from historic maps and aerial photography, reveal considerable decadal-scale variations in cliff recession, within which are nested inter-annual fluctuations in rates of retreat. Archival datasets on significant periods of onshore winds and their interaction with high water levels (including the incidence of storm surges) and rainstorm events are used to determine thresholds for cliff base erosion and its propagation upwards through the cliff profile. In addition, the ‘GEO-Slope' dynamic coupled hydrology-stability model is used to establish thresholds for cliff face failures driven by variations in rainfall inputs. Retreat mechanisms are complex, governed by cliff geology, both as a primary control on suction loss and through its interaction with basal marine conditions. The study allows a general model of cliff retreat for soft rock cliffs to be put forward, whereby a resistant basal platform is overlain by more erodible, weakly and moderately cemented sands and gravels. In this model, the varying balance between marine and terrestrial forcing factors are reflected in low (< 4 m a- 1), intermediate (4-7 m a- 1) and high (> 7 m a- 1) modes of cliff retreat.

  6. Gully head retreat rates in the semi-arid highlands of Northern Ethiopia

    NASA Astrophysics Data System (ADS)

    Frankl, Amaury; Poesen, Jean; Deckers, Jozef; Haile, Mitiku; Nyssen, Jan

    2012-11-01

    Due to overgrazing and agricultural intensification, gully erosion severely affects sub-Saharan countries; however, insufficient quantitative studies exist for this part of the world. This paper presents data on gully head retreat rates in Northern Ethiopia and relates these rates to gully and environmental characteristics. The monitoring of headcuts over one rainy season (2010) revealed that present-day retreat rates are low, with average annual linear (Rl), areal (Ra) and volumetric (Ve) retreat rates of 0.34 m y- 1, 1.70 m2 y- 1 and 5.2 m3 y- 1, respectively. These results express the positive effects of recent soil and water conservation practices on gully stabilization. Significantly higher values of Rl (up to 1.93 m y- 1) occurred in the Vertisol areas affected by soil piping. When considering the medium- to long time scale (1-47 years) using archival terrestrial (and aerial) photographs, headcut retreat rates proved to be significantly higher than those in the short term. The averages for Rl, Ra and Ve are 3.8 m y- 1, 31.5 m2 y- 1 and 47.7 m3 y- 1, respectively. Retreat rates are up to 10 times higher after road construction. For the medium to long term, headcut retreat rates were positively related to the catchment area (A). A power relationship that best describes the relation between Ve and A is Ve = 0.53 A0.31 (r2 = 0.27, n = 18). Compared to other areas worldwide, regressive erosion has been rapid in Ethiopia as a result of the degraded and steep landscape combined with erosive rains and the occurrence of Vertisols. In Vertisols, headcut retreat is controlled by soil piping. Because no adequate techniques exist to control gully initiation and development in Vertisols, alternative techniques should be developed that deactivate soil pipes.

  7. Benthic Trophic Interactions in an Antarctic Shallow Water Ecosystem Affected by Recent Glacier Retreat.

    PubMed

    Pasotti, Francesca; Saravia, Leonardo Ariel; De Troch, Marleen; Tarantelli, Maria Soledad; Sahade, Ricardo; Vanreusel, Ann

    2015-01-01

    The western Antarctic Peninsula is experiencing strong environmental changes as a consequence of ongoing regional warming. Glaciers in the area are retreating rapidly and increased sediment-laden meltwater runoff threatens the benthic biodiversity at shallow depths. We identified three sites with a distinct glacier-retreat related history and different levels of glacial influence in the inner part of Potter Cove (King George Island, South Shetland Islands), a fjord-like embayment impacted since the 1950s by a tidewater glacier retreat. We compared the soft sediment meio- and macrofauna isotopic niche widths (δ13C and δ15N stable isotope analysis) at the three sites to investigate possible glacier retreat-related influences on benthic trophic interactions. The isotopic niches were locally shaped by the different degrees of glacier retreat-related disturbance within the Cove. Wider isotopic niche widths were found at the site that has become ice-free most recently, and narrower niches at the older ice-free sites. At an intermediate state of glacier retreat-related disturbance (e.g. via ice-growler scouring) species with different strategies could settle. The site at the earliest stage of post-retreat development was characterized by an assemblage with lower trophic redundancy. Generally, the isotopic niche widths increased with increasing size spectra of organisms within the community, excepting the youngest assemblage, where the pioneer colonizer meiofauna size class displayed the highest isotopic niche width. Meiofauna at all sites generally occupied positions in the isotopic space that suggested a detrital-pool food source and/or the presence of predatory taxa. In general ice scour and glacial impact appeared to play a two-fold role within the Cove: i) either stimulating trophic diversity by allowing continuous re-colonization of meiofaunal species or, ii) over time driving the benthic assemblages into a more compact trophic structure with increased

  8. Benthic Trophic Interactions in an Antarctic Shallow Water Ecosystem Affected by Recent Glacier Retreat

    PubMed Central

    Pasotti, Francesca; Saravia, Leonardo Ariel; De Troch, Marleen; Tarantelli, Maria Soledad; Sahade, Ricardo; Vanreusel, Ann

    2015-01-01

    The western Antarctic Peninsula is experiencing strong environmental changes as a consequence of ongoing regional warming. Glaciers in the area are retreating rapidly and increased sediment-laden meltwater runoff threatens the benthic biodiversity at shallow depths. We identified three sites with a distinct glacier-retreat related history and different levels of glacial influence in the inner part of Potter Cove (King George Island, South Shetland Islands), a fjord-like embayment impacted since the 1950s by a tidewater glacier retreat. We compared the soft sediment meio- and macrofauna isotopic niche widths (δ13C and δ15N stable isotope analysis) at the three sites to investigate possible glacier retreat-related influences on benthic trophic interactions. The isotopic niches were locally shaped by the different degrees of glacier retreat-related disturbance within the Cove. Wider isotopic niche widths were found at the site that has become ice-free most recently, and narrower niches at the older ice-free sites. At an intermediate state of glacier retreat-related disturbance (e.g. via ice-growler scouring) species with different strategies could settle. The site at the earliest stage of post-retreat development was characterized by an assemblage with lower trophic redundancy. Generally, the isotopic niche widths increased with increasing size spectra of organisms within the community, excepting the youngest assemblage, where the pioneer colonizer meiofauna size class displayed the highest isotopic niche width. Meiofauna at all sites generally occupied positions in the isotopic space that suggested a detrital-pool food source and/or the presence of predatory taxa. In general ice scour and glacial impact appeared to play a two-fold role within the Cove: i) either stimulating trophic diversity by allowing continuous re-colonization of meiofaunal species or, ii) over time driving the benthic assemblages into a more compact trophic structure with increased

  9. Coupled ice shelf-ocean modeling and complex grounding line retreat from a seabed ridge

    NASA Astrophysics Data System (ADS)

    De Rydt, J.; Gudmundsson, G. H.

    2016-05-01

    Recent observations and modeling work have shown a complex mechanical coupling between Antarctica's floating ice shelves and the adjacent grounded ice sheet. A prime example is Pine Island Glacier, West Antarctica, which has a strong negative mass balance caused by a recent increase in ocean-induced melting of its ice shelf. The mass loss coincides with the retreat of the grounding line from a seabed ridge, on which it was at least partly grounded until the 1970s. At present, it is unclear what has caused the onset of this retreat and how feedback mechanisms between the ocean and ice shelf geometry have influenced the ice dynamics. To address these questions, we present the first results from an offline coupling between a state-of-the-art shallow-ice flow model with grounding line resolving capabilities and a three-dimensional ocean general circulation model with a static implementation of the ice shelf. A series of idealized experiments simulate the retreat from a seabed ridge in response to changes in the ocean forcing, and we show that the retreat becomes irreversible after 20 years of warm ocean conditions. A comparison to experiments with a simple depth-dependent melt rate parameterization demonstrates that such parameterizations are unable to capture the details of the retreat process, and they overestimate mass loss by more than 40% over a 50 year timescale.

  10. Characteristics and treatment outcomes of tuberculosis retreatment cases in three regional hospitals, Uganda

    PubMed Central

    Reid, A. J.; Fujiwara, P. I.; Mugabe, F.; Kosgei, R. J.; Tayler-Smith, K.; Kizito, W.; Joloba, M.

    2013-01-01

    Setting: Three regional referral hospitals in Uganda with a high burden of tuberculosis (TB) and human immunodeficiency virus (HIV) cases. Objective: To determine the treatment outcomes of TB retreatment cases and factors influencing these outcomes. Design: A retrospective cohort study of routinely collected National Tuberculosis Programme data between 1 January 2009 and 31 December 2010. Results: The study included 331 retreatment patients (68% males), with a median age of 36 years, 93 (28%) of whom were relapse smear-positive, 21 (6%) treatment after failure, 159 (48%) return after loss to follow-up, 26 (8%) relapse smear-negative and 32 (10%) relapse cases with no smear performed. Treatment success rates for all categories of retreatment cases ranged between 28% and 54%. Relapse smear-positive (P = 0.002) and treatment after failure (P = 0.038) cases were less likely to have a successful treatment outcome. Only 32% of the retreatment cases received a Category II treatment regimen; there was no difference in treatment success among patients who received Category II or Category I treatment regimens (P = 0.73). Conclusion: Management of TB retreatment cases and treatment success for all categories in three referral hospitals in Uganda was poor. Relapse smear-positive or treatment after failure cases were less likely to have a successful treatment outcome. PMID:26393019

  11. Wastewater retreatment and reuse system for agricultural irrigation in rural villages.

    PubMed

    Kim, Minyoung; Lee, Hyejin; Kim, Minkyeong; Kang, Donghyeon; Kim, Dongeok; Kim, YoungJin; Lee, Sangbong

    2014-01-01

    Climate changes and continuous population growth increase water demands that will not be met by traditional water resources, like surface and ground water. To handle increased water demand, treated municipal wastewater is offered to farmers for agricultural irrigation. This study aimed to enhance the effluent quality from worn-out sewage treatment facilities in rural villages, retreat effluent to meet water quality criteria for irrigation, and assess any health-related and environmental impacts from using retreated wastewater irrigation on crops and in soil. We developed the compact wastewater retreatment and reuse system (WRRS), equipped with filters, ultraviolet light, and bubble elements. A pilot greenhouse experiment was conducted to evaluate lettuce growth patterns and quantify the heavy metal concentration and pathogenic microorganisms on lettuce and in soil after irrigating with tap water, treated wastewater, and WRRS retreated wastewater. The purification performance of each WRRS component was also assessed. The study findings revealed that existing worn-out sewage treatment facilities in rural villages could meet the water quality criteria for treated effluent and also reuse retreated wastewater for crop growth and other miscellaneous agricultural purposes. PMID:25521131

  12. Coupled ice shelf-ocean modeling and complex grounding line retreat for Pine Island Glacier

    NASA Astrophysics Data System (ADS)

    De Rydt, Jan; Gudmundsson, Hilmar

    2016-04-01

    Recent observations and modeling work have shown a complex mechanical coupling between Antarctica's floating ice shelves and the adjacent grounded ice sheet. A prime example is Pine Island Glacier, West Antarctica, which has a strong negative mass balance caused by a recent increase in ocean-induced melting of its ice shelf. The mass loss coincides with the retreat of the grounding line from a seabed ridge, on which it was at least partly grounded until the 1970s. At present, it is unclear what has caused the onset of this retreat, and how feedback mechanisms between the ocean and iceshelf geometry have influenced the ice dynamics. To address these questions, we present results from an offline coupling between a state-of-the-art shallow-ice flow model with grounding line resolving capabilities, and a three-dimensional ocean general circulation model with a static implementation of the ice shelf. A series of idealized experiments simulate the retreat from a seabed ridge in response to changes in the ocean forcing, and we show that the retreat becomes irreversible after 20 years of warm ocean conditions. A comparison to experiments with a simple depth-dependent meltrate parameterisation demonstrates that such parameterizations are unable to capture the details of the retreat process, and they overestimate mass loss by more than 40% over a 50-year timescale.

  13. Analysis of Environmental Forcing and Melange Fluctuation in Asynchronous Retreat of Ocean Terminating Glaciers in Greenland's Sermilik Fjord

    NASA Astrophysics Data System (ADS)

    Seifert, F.; Galey, C. E.; Bassis, J. N.

    2014-12-01

    Widespread near synchronous retreat of marine terminating outlet glaciers has been observed across wide swaths of the Greenland Ice Sheet. However, despite large-scale patterns of retreat, there is considerable variability in the timing and retreat patterns of individual glaciers with geographically adjacent glaciers that experience similar climate and meteorological forcing displaying markedly different behavior. Here we applied an automated identification algorithm that we developed to track the terminus and melange in order better understand the complex dynamics and varying drivers of glacier retreat. The algorithm was applied to three major glaciers (Helheim Glacier, Fenris Glacier and Midgard Glacier) that terminate in Greenland's Sermilik Fjord over the period of 2000- 2014. The terminus position and the percentage of the fjord filled with melange or sea ice from 2001 to present was determined. Since these glaciers exist within the same fjord system, they should experience comparable environmental forcing conditions, but appear to respond to these conditions differently causing them to have varying patterns of retreat. Helheim Glacier and Fenris Glacier have terminus locations closely spaced in the fjord but Helheim Glacier's terminus retreated over 7 km before advancing to stabilize at a 5 km retreat over the observation period and Fenris Glacier's terminus has stayed in roughly the same place. Midgard Glacier is located across the fjord from Helheim Glacier and its terminus has continuously retreated with a retreat of approximately 8 km. This asynchronous retreat shows that proximity alone cannot determine retreat behavior, and a more complex interaction between internal variability and external forcing must be taking place. To better understand the variability within the system and the cause of asynchronous retreat, ocean and air temperature datasets, in conjunction with the fjord geometry, were compared with our derived melange/sea ice and terminus

  14. Antarctic last interglacial isotope peak in response to sea ice retreat not ice-sheet collapse.

    PubMed

    Holloway, Max D; Sime, Louise C; Singarayer, Joy S; Tindall, Julia C; Bunch, Pete; Valdes, Paul J

    2016-01-01

    Several studies have suggested that sea-level rise during the last interglacial implies retreat of the West Antarctic Ice Sheet (WAIS). The prevalent hypothesis is that the retreat coincided with the peak Antarctic temperature and stable water isotope values from 128,000 years ago (128 ka); very early in the last interglacial. Here, by analysing climate model simulations of last interglacial WAIS loss featuring water isotopes, we show instead that the isotopic response to WAIS loss is in opposition to the isotopic evidence at 128 ka. Instead, a reduction in winter sea ice area of 65±7% fully explains the 128 ka ice core evidence. Our finding of a marked retreat of the sea ice at 128 ka demonstrates the sensitivity of Antarctic sea ice extent to climate warming. PMID:27526639

  15. Retreatment of patients who do not respond to initial therapy for chronic hepatitis C.

    PubMed

    Shiffman, Mitchell L

    2004-05-01

    Despite improvements in the treatment of chronic hepatitis C virus (HCV) infection, nearly half of all patients do not respond to initial therapy. Retreatment of these patients with pegylated interferon and ribavirin has been successful in only a limited percentage of cases. Factors associated with sustained virologic response (SVR) following retreatment include prior treatment with interferon monotherapy, HCV genotype 2 or 3, a low serum HCV RNA level, and the absence of cirrhosis. Fewer than 6% of nonresponders who were previously treated with interferon and ribavirin and who have cirrhosis, genotype 1, and a high viral load achieve SVR following retreatment with pegylated interferon and ribavirin. No therapy has been shown to yield SVR in patients who do not respond to pegylated interferon and ribavirin. Long-term maintenance therapy with pegylated interferon is currently being evaluated in nonresponders with advanced fibrosis and cirrhosis. Its use should be considered investigational at this time. PMID:15468612

  16. Patellofemoral pain: proximal, distal, and local factors, 2nd International Research Retreat.

    PubMed

    Powers, Christopher M; Bolgla, Lori A; Callaghan, Michael J; Collins, Natalie; Sheehan, Francis T

    2012-06-01

    Patellofemoral pain (PFP) is one of the most common lower extremity conditions seen in orthopaedic practice. The mission of the second International Patellofemoral Pain Research Retreat was to bring together scientists and clinicians from around the world who are conducting research aimed at understanding the factors that contribute to the development and, consequently, the treatment of PFP. The format of the 2.5-day retreat included 2 keynote presentations, interspersed with 6 podium and 4 poster sessions. An important element of the retreat was the development of consensus statements that summarized the state of the research in each of the 4 presentation categories. In this supplement, you will find the consensus documents from the meeting, as well as the keynote addresses, schedule, and platform and poster presentation abstracts. PMID:22660660

  17. Radioiodine uptake following iodine-131 therapy for Graves' disease: an early indicator of need for retreatment

    SciTech Connect

    Carpentier, W.R.; Gilliland, P.F.; Piziak, V.K.; Petty, F.C.; McConnell, B.G.; Verdonk, C.A.; Ibarra, J.D.; Thompson, J.Q.

    1989-01-01

    Forty-five patients with Graves' disease were studied prospectively to determine if 24-hour I-131 uptake measurements alone or in combination with serum thyroid hormone levels at six weeks would determine the necessity for retreatment of the thyrotoxicosis. All patients with an I-131 uptake greater than 30% at six weeks required retreatment. No patient with an I-131 uptake of less than 15% required retreatment. Patients with uptakes between 15% and 30% were variable. An elevated free thyroxin index at 6 weeks is not helpful to determine which patients will remain thyrotoxic. Patients with a free thyroxin index within the normal range at six weeks can be predicted to be euthyroid by 12 weeks if their 24-hour I-131 uptake is between 15% and 30% and to be hypothyroid if their 24-hour I-131 uptake is below 15%. There was no difference between patient groups treated initially with antithyroid medication and those who were not.

  18. Fast retreat of Zachariæ Isstrøm, northeast Greenland.

    PubMed

    Mouginot, J; Rignot, E; Scheuchl, B; Fenty, I; Khazendar, A; Morlighem, M; Buzzi, A; Paden, J

    2015-12-11

    After 8 years of decay of its ice shelf, Zachariæ Isstrøm, a major glacier of northeast Greenland that holds a 0.5-meter sea-level rise equivalent, entered a phase of accelerated retreat in fall 2012. The acceleration rate of its ice velocity tripled, melting of its residual ice shelf and thinning of its grounded portion doubled, and calving is now occurring at its grounding line. Warmer air and ocean temperatures have caused the glacier to detach from a stabilizing sill and retreat rapidly along a downward-sloping, marine-based bed. Its equal-ice-volume neighbor, Nioghalvfjerdsfjorden, is also melting rapidly but retreating slowly along an upward-sloping bed. The destabilization of this marine-based sector will increase sea-level rise from the Greenland Ice Sheet for decades to come. PMID:26563135

  19. Fast retreat of Zachariæ Isstrøm, northeast Greenland

    NASA Astrophysics Data System (ADS)

    Mouginot, J.; Rignot, E.; Scheuchl, B.; Fenty, I.; Khazendar, A.; Morlighem, M.; Buzzi, A.; Paden, J.

    2015-12-01

    After 8 years of decay of its ice shelf, Zachariæ Isstrøm, a major glacier of northeast Greenland that holds a 0.5-meter sea-level rise equivalent, entered a phase of accelerated retreat in fall 2012. The acceleration rate of its ice velocity tripled, melting of its residual ice shelf and thinning of its grounded portion doubled, and calving is now occurring at its grounding line. Warmer air and ocean temperatures have caused the glacier to detach from a stabilizing sill and retreat rapidly along a downward-sloping, marine-based bed. Its equal-ice-volume neighbor, Nioghalvfjerdsfjorden, is also melting rapidly but retreating slowly along an upward-sloping bed. The destabilization of this marine-based sector will increase sea-level rise from the Greenland Ice Sheet for decades to come.

  20. Antarctic last interglacial isotope peak in response to sea ice retreat not ice-sheet collapse

    PubMed Central

    Holloway, Max D.; Sime, Louise C.; Singarayer, Joy S.; Tindall, Julia C.; Bunch, Pete; Valdes, Paul J.

    2016-01-01

    Several studies have suggested that sea-level rise during the last interglacial implies retreat of the West Antarctic Ice Sheet (WAIS). The prevalent hypothesis is that the retreat coincided with the peak Antarctic temperature and stable water isotope values from 128,000 years ago (128 ka); very early in the last interglacial. Here, by analysing climate model simulations of last interglacial WAIS loss featuring water isotopes, we show instead that the isotopic response to WAIS loss is in opposition to the isotopic evidence at 128 ka. Instead, a reduction in winter sea ice area of 65±7% fully explains the 128 ka ice core evidence. Our finding of a marked retreat of the sea ice at 128 ka demonstrates the sensitivity of Antarctic sea ice extent to climate warming. PMID:27526639

  1. Modelling river bank retreat by combining fluvial erosion, seepage and mass failure

    NASA Astrophysics Data System (ADS)

    Dapporto, S.; Rinaldi, M.

    2003-04-01

    Streambank erosion processes contribute significantly to the sediment yielded from a river system and represent an important issue in the contexts of soil degradation and river management. Bank retreat is controlled by a complex interaction of hydrologic, geotechnical, and hydraulic processes. The capability of modelling these different components allows for a full reconstruction and comprehension of the causes and rates of bank erosion. River bank retreat during a single flow event has been modelled by combining simulation of fluvial erosion, seepage, and mass failures. The study site, along the Sieve River (Central Italy), has been subject to extensive researches, including monitoring of pore water pressures for a period of 4 years. The simulation reconstructs fairly faithfully the observed changes, and is used to: a) test the potentiality and discuss advantages and limitations of such type of methodology for modelling bank retreat; c) quantify the contribution and mutual role of the different processes determining bank retreat. The hydrograph of the event is divided in a series of time steps. Modelling of the riverbank retreat includes for each step the following components: a) fluvial erosion and consequent changes in bank geometry; b) finite element seepage analysis; c) stability analysis by limit equilibrium method. Direct fluvial shear erosion is computed using empirically derived relationships expressing lateral erosion rate as a function of the excess of shear stress to the critical entrainment value for the different materials along the bank profile. Lateral erosion rate has been calibrated on the basis of the total bank retreat measured by digital terrestrial photogrammetry. Finite element seepage analysis is then conducted to reconstruct the saturated and unsaturated flow within the bank and the pore water pressure distribution for each time step. The safety factor for mass failures is then computed, using the pore water pressure distribution obtained

  2. Glycated hemoglobin screening identifies patients admitted for retreatment of tuberculosis at risk for diabetes in Tanzania

    PubMed Central

    Sariko, Margaretha L; Mpagama, Stellah G; Gratz, Jean; Kisonga, Riziki; Saidi, Queen; Kibiki, Gibson S; Heysell, Scott K

    2016-01-01

    Introduction World Health Organization recommendations of bidirectional screening for tuberculosis (TB) and diabetes have been met with varying levels of uptake by national TB programs in resource-limited settings. Methodology Kibong’oto Infectious Diseases Hospital (KIDH) is a referral hospital for TB from northern Tanzania, and the national referral hospital for multidrug-resistant (MDR)-TB. Glycated hemoglobin (HgbA1c) testing was done on patients admitted to KIDH for newly diagnosed TB, retreatment TB, and MDR-TB, to determine the point prevalence of diabetes (HgbA1c ≥ 6.5%) and prediabetes (HgbA1c 5.7%– 6.4%). Results Of 148 patients hospitalized at KIDH over a single week, 59 (38%) had no prior TB treatment, 22 (15%) were retreatment cases, and 69 (47%) had MDR-TB. Only 3 (2%) had a known history of diabetes. A total of 144 (97%) had successful screening, of which 110 (77%) had an HgbA1c ≤ 5.6%, 28 (19%) had ≥ 5.7 < 6.5, and 6 (4%) had ≥ 6.5. Comparing subjects with prediabetes or diabetes to those with normal A1c levels, retreatment patients were significantly more likely to have a A1c ≥ 5.7% (odds ratio: 3.2, 95% CI: 1.2–9.0; p = 0.02) compared to those without prior TB treatment. No retreatment case was a known diabetic, thus the number needed to screen to diagnose one new case of diabetes among retreatment cases was 11. Conclusions Diabetes prevalence by HgbA1c was less common than expected, but higher HgA1c values were significantly more frequent among retreatment cases, allowing for a rational, resource-conscious screening approach. PMID:27131008

  3. A Retrospective Analysis of the Retreatment of Failed Sinus Bone Grafts.

    PubMed

    Kim, Young-Kyun; Kim, Su-Gwan

    2016-06-01

    This analysis examined the types of retreatment in failed sinus bone grafts due to the development of maxillary sinusitis. Reoperation was performed in 7 patients. The types of reoperation included infection management, reconstruction of the sinus roof using a pedicled buccal fat pad and collagen membrane, oroantral fistula closure, sinus bone graft using an autogenous bone graft, and implant placement. In one case, sinusitis developed 14 months after the reoperation, but it was managed by incision, drainage, and administration of antibiotics. All sinus bone grafts that were performed during the retreatments were successful. PMID:27058356

  4. Rift in Antarctic Glacier: a Unique Chance to Study Ice Shelf Retreat

    NASA Technical Reports Server (NTRS)

    Howat, Ian M.; Jezek, Ken; Studinger, Michael; Macgregor, Joseph A.; Paden, John; Floricioiu, Dana; Russell, Rob; Linkswiler, Matt; Dominguez, Roseanne T.

    2012-01-01

    It happened again, but this time it was caught in the act. During the last week of September 2011 a large transverse rift developed across thefloating terminus of West Antarcticas PineIsland Glacier, less than 5 years after its lastlarge calving event, in 2007 (Figure 1). PineIsland Glaciers retreat has accelerated substantiallyin the past 2 decades, and it is nowlosing 50 gigatons of ice per year, or roughly 25 of Antarcticas total annual contributionto sea level rise [Rignot et al., 2008]. The glaciers recent accelerated retreat is likely triggered by ocean warming and increased submarine melting. As such, it is of significant interest to glaciologists and of heightened societal relevance.

  5. Linking permafrost distribution, glacial retreat and colluvial sediment dynamics in the Saldur River basin, Eastern Italian Alps

    NASA Astrophysics Data System (ADS)

    Brardinoni, Francesco; Sosio, Rosanna; Scotti, Riccardo; Cavalli, Marco; Comiti, Francesco; Mair, Volkmar

    2014-05-01

    In the last three decades generalized atmospheric temperature rise has produced rapid glacial retreat and permafrost degradation in high mountain environments of the European Alps. While it is widely recognized that these changes can impart general instability to mountain slopes (i.e., several projects have documented single case studies of high magnitude-low frequency, catastrophic slope failures), to our knowledge, there appears to be little empirical data available for investigating the spatial distribution of mass-wasting intensity through time in high mountain areas in relation to permafrost degradation and deglaciation patterns. This is a critical shortcoming. Understanding and quantifying the influence of similar transient conditions on mass-wasting processes holds critical long-term implications on the overall sediment flux reshaping mountain landscapes (e.g., post-LGM landscape evolution), as well as more practical short-term applications on water quality issues, damage control/prevention to infrastructure, and reservoir siltation, to mention some. In this contribution we present an integrated approach that aims to: (i) document the spatial distribution of mass-wasting activity and sediment production in the Saldur River basin (97 km^2); (ii) detect causal linkages between mass-wasting intensity, the potential spatial distribution of discontinuous permafrost, and patterns of glacier retreat; and (iii) identify source-to-sink colluvial sedimentary pathways as modulated by the spatial organization of glacial and periglacial landforms. To these ends, we map rock glaciers, protalus ramparts and moraines, and compile a field- and air photo-based multi-temporal (1959-2012) inventory of colluvial sediment sources. We then combine these data with two historical datasets of debris flow and landslide events (both implemented and maintained by the Autonomous Province of Bolzano) and analyse mass-wasting spatial distribution and intensity in relation to proximity of

  6. Longitudinal spin fluctuations in nickel

    SciTech Connect

    Boeni, P. , Villigen ); Martinez, J.L. ); Tranquada, J.M. )

    1989-10-10

    The longitudinal and transverse spin fluctuations in Ni have been measured below {Tc} by means of polarized neutron scattering in the momentum range 0.06 < q < 0.18 {angstrom}{sup -1}. In transverse scans spin wave peaks at E{sub q} = Dq{sup 2} appear as expected from early measurements performed with unpolarized neutrons. The longitudinal magnetic scattering {sub {chi}L}(q, E), on the other hand, is quasielastic without any signature of inelastic peaks near E{sub q}. The q and T dependences of {sub {chi}L}(q, E) resemble the paramagnetic scattering above {Tc}, i.e., the linewidth is roughly proportional to q{sup 2.5} and the integrated intensity I(q) is proportional to (q{sup 2} + {kappa}{sub z}{sup 2}){sup -1}. 8 refs., 3 figs.

  7. Effects of ongoing glacier retreat on steep valley-side drift slopes in the upper Bødalen valley, western Norway

    NASA Astrophysics Data System (ADS)

    Laute, Katja; Beylich, Achim A.; Oppikofer, Thierry

    2013-04-01

    The general pattern and dominant trend of today's mountain glaciers worldwide is a retreat of glacier fronts, indicating a significant volume decrease. Negative glacier net balances have been recorded for all Scandinavian glaciers after 1999. The ongoing glacier retreat enlarges freshly exposed proglacial areas which are characterized by e.g. comparably higher intensities of denudational slope processes and higher sediment availability. This study focuses on influences of rapid glacier regression on contemporary surface processes acting on steep valley-side drift slopes in a characteristic steep, parabolic-shaped and glacier-fed valley (Bødalen,) located on the western side of the Jostedalsbreen ice cap in western Norway. The Bødalsbreen is one of the glaciers with the highest retreat rate in entire Norway. Since the Little Ice Age (LIA) glacier maximum advance (1750) the glacier retreated ca. 1.500 m, including 65 m of retreat within the period of 2001 to 2010. Due to this retreat large areas of unstable hillslopes covered by glacial deposits from the LIA lateral moraines have been exposed. A combination of high resolution terrestrial laser scanning (TLS) and a designed monitoring program has been applied to a selected hillslope site on the eastern flank of the Bødalsbreen. Three sequential terrestrial laser scans have been acquired in the summers of 2010, 2011 and 2012. The analysis of the three series of the high resolution point clouds enables (i) the detection of unstable slope areas, (ii) areas characterized primarily by erosion or deposition processes and (iii) to quantify volumes of mass transfers at the scanned site. The results from the TLS measurements are combined with the results from the monitoring program (installations in operation since 2009) which includes remote cameras for monitoring rapid mass movement events (avalanches, slush- and debris flows), stone tracer lines for measuring surface movements as well as temperature loggers both in rock

  8. Joint multiple imputation for longitudinal outcomes and clinical events that truncate longitudinal follow-up.

    PubMed

    Hu, Bo; Li, Liang; Greene, Tom

    2016-07-30

    Longitudinal cohort studies often collect both repeated measurements of longitudinal outcomes and times to clinical events whose occurrence precludes further longitudinal measurements. Although joint modeling of the clinical events and the longitudinal data can be used to provide valid statistical inference for target estimands in certain contexts, the application of joint models in medical literature is currently rather restricted because of the complexity of the joint models and the intensive computation involved. We propose a multiple imputation approach to jointly impute missing data of both the longitudinal and clinical event outcomes. With complete imputed datasets, analysts are then able to use simple and transparent statistical methods and standard statistical software to perform various analyses without dealing with the complications of missing data and joint modeling. We show that the proposed multiple imputation approach is flexible and easy to implement in practice. Numerical results are also provided to demonstrate its performance. Copyright © 2015 John Wiley & Sons, Ltd. PMID:26179943

  9. Increasing the Relevance of Research to Underserved Communities: Lessons Learned from a Retreat to Engage Community Health Workers with Researchers

    PubMed Central

    Angier, Heather; Wiggins, Noelle; Gregg, Jessica; Gold, Rachel; DeVoe, Jennifer

    2016-01-01

    Summary This article presents information on a community retreat developed to seek input from community health workers (CHWs) to increase the relevance of our research to underserved communities in Oregon. Retreats facilitating dialogue between researchers and CHWs could yield important insight to enhance the significance of research for communities. PMID:23728049

  10. Radiocarbon deglaciation chronology of the Thunder Bay, Ontario area and implications for ice sheet retreat patterns

    NASA Astrophysics Data System (ADS)

    Lowell, Thomas V.; Fisher, Timothy G.; Hajdas, I.; Glover, K.; Loope, H.; Henry, T.

    2009-08-01

    The sensitivity of ice sheets to climate change influences the return of meltwater to the oceans. Here we track the Laurentide Ice Sheet along a ˜400 km long transect spanning about 6000 yr of retreat during the major climate oscillations of the lateglacial. Thunder Bay, Ontario is near a major topographic drainage divide, thus terrestrial ablation processes are the primary forcers of ice margin recession in the study area. During deglaciation three major moraine sets were produced, and have been assigned minimum ages of 13.9 ± 0.2, 12.3 ± 0.2-12.1 ± 0.1, and 11.2 ± 0.2 cal ka BP from south to north. These define a slow retreat (˜10-50 m/a) prior to major climate oscillations which was then followed by a factor of ˜2 increase during the Bölling-Alleröd, and an additional increase during the early Holocene. When compared to retreat rates in other terrestrial settings of the ice sheet, nearly identical patterns emerge. However this becomes problematic because a key control on retreat rates is the surface slope of the ice sheet and this should vary considerably over areas of so-called hard and soft beds. Further these ice margin reconstructions would not allow meltwater sourced in the Hudson Basin to drain into the Atlantic basin until after Younger Dryas time.

  11. They're M-e-e-elting!: An Investigation of Glacial Retreat in Antarctica

    ERIC Educational Resources Information Center

    Bugg, Samuel R., IV; Constible, Juanita; Kaput, Marianne; Lee, Richard E., Jr.

    2007-01-01

    In this article, the authors describe the mechanics of They're M-e-e-elting!, an activity wherein middle school students can simulate glacial retreat in Antarctica. They're M-e-e-elting! allows students to melt glaciers, change the water level and salinity of the Southern Ocean, and examine alterations to the Antarctic food web--all without…

  12. The Role of Adherence and Retreatment in De Novo Emergence of MDR-TB.

    PubMed

    Cadosch, Dominique; Abel Zur Wiesch, Pia; Kouyos, Roger; Bonhoeffer, Sebastian

    2016-03-01

    Treatment failure after therapy of pulmonary tuberculosis (TB) infections is an important challenge, especially when it coincides with de novo emergence of multi-drug-resistant TB (MDR-TB). We seek to explore possible causes why MDR-TB has been found to occur much more often in patients with a history of previous treatment. We develop a mathematical model of the replication of Mycobacterium tuberculosis within a patient reflecting the compartments of macrophages, granulomas, and open cavities as well as parameterizing the effects of drugs on the pathogen dynamics in these compartments. We use this model to study the influence of patient adherence to therapy and of common retreatment regimens on treatment outcome. As expected, the simulations show that treatment success increases with increasing adherence. However, treatment occasionally fails even under perfect adherence due to interpatient variability in pharmacological parameters. The risk of generating MDR de novo is highest between 40% and 80% adherence. Importantly, our simulations highlight the double-edged effect of retreatment: On the one hand, the recommended retreatment regimen increases the overall success rate compared to re-treating with the initial regimen. On the other hand, it increases the probability to accumulate more resistant genotypes. We conclude that treatment adherence is a key factor for a positive outcome, and that screening for resistant strains is advisable after treatment failure or relapse. PMID:26967493

  13. Grounding line retreat of Totten Glacier, East Antarctica, 1996 to 2013

    NASA Astrophysics Data System (ADS)

    Li, Xin; Rignot, Eric; Morlighem, Mathieu; Mouginot, Jeremie; Scheuchl, Bernd

    2015-10-01

    Totten Glacier, East Antarctica, a glacier that holds a 3.9 m sea level change equivalent, has thinned and lost mass for decades. We map its grounding line positions in 1996 and 2013 using differential radar interferometry (InSAR) data and develop precise, high-resolution topographies of its ice surface and ice draft using NASA Operation IceBridge data, InSAR data, and a mass conservation method. We detect a 1 to 3 km retreat of the grounding line in 17 years. The retreat is asymmetrical along a two-lobe pattern, where ice is only grounded a few 10 m above sea level, or ice plain, which may unground further with only modest amounts of ice thinning. The pattern of retreat indicates ice thinning of 12 m in 17 years or 0.7±0.1 m/yr at the grounding line on average. Sustained thinning will cause further grounding line retreat but may not be conducive to a marine instability.

  14. Retreating behavior of a charged ionic liquid droplet in a dielectric liquid under electric field

    NASA Astrophysics Data System (ADS)

    Ahn, Myung Mo; Im, Do Jin; Kang, In Seok

    2013-11-01

    Ionic liquids show great promise as excellent solvents or catalysts in energy and biological fields due to their unique chemical and physical properties. The ionic liquid droplets in microfluidic systems can also be used as a potential platform for chemical biological reactions. In order to control electrically the ionic liquid droplets in a microfluidic device, the charging characteristics of ionic liquid droplets need to be understood. In this work, the charging characteristics of various ionic liquids are investigated by using the parallel plate electrodes system. Under normal situation, a charged droplet shows bouncing motion between electrodes continuously. However, for some special ionic liquids, interesting retreating behavior of charged ionic liquid droplet has been observed. This retreating behavior of ionic liquid droplet has been analyzed experimentally by the image analysis and the electrometer signal analysis. Based on the hypothesis of charge leakage of the retreating ionic liquid droplets, FT-IR spectroscopy analysis has also been performed. The retreating behavior of ionic liquid droplet is discussed from the intermolecular point of view according to the species of ionic liquids. This research was supported by grant No. 2013R1A1A2011956 funded by the Ministry of Science, ICT and Future Planning (MSIP) and by grant No. 2013R1A1A2010483 funded by the Ministry of Education, Science and Technology (MEST) through the NRF.

  15. Rapid marine deglaciation: asynchronous retreat dynamics between the Irish Sea Ice Stream and terrestrial outlet glaciers

    NASA Astrophysics Data System (ADS)

    Patton, H.; Hubbard, A.; Bradwell, T.; Glasser, N. F.; Hambrey, M. J.; Clark, C. D.

    2013-08-01

    Understanding the retreat behaviour of past marine-ice sheets provides vital context to accurate assessment of the present stability and long-term response of contemporary polar-ice sheets to climate and oceanic warming. Here new multibeam swath-bathymetry data and sedimentological analysis are combined with high resolution ice-sheet modelling to reveal complex landform assemblages and process-dynamics associated with deglaciation of the British-Celtic Ice Sheet (BCIS) within the Irish Sea Basin. Our reconstruction indicates a non-linear relationship between the rapidly receding Irish Sea Ice Stream, the largest draining the BCIS, and the retreat of outlet glaciers draining the adjacent, terrestrially based ice sheet centred over Wales. Retreat of Welsh ice was episodic; superimposed over low-order oscillations of its margin are asynchronous outlet re-advances driven by catchment-wide mass balance variations that are amplified through migration of the ice cap's main ice-divide. Formation of large, linear ridges which extend at least 12.5 km offshore (locally known as sarns) and dominate the regional bathymetry are attributed to repeated frontal and medial morainic deposition associated with the re-advancing phases of these outlet glaciers. Our study provides new insight into ice-sheet extent, dynamics and non-linear retreat across a major palaeo-ice stream confluence zone, and has ramifications for the interpretation of recent fluctuations observed by satellites over short-time scales across marine-sectors of the Greenland and Antarctic ice sheets.

  16. Rapid marine deglaciation: asynchronous retreat dynamics between the Irish Sea Ice Stream and terrestrial outlet glaciers

    NASA Astrophysics Data System (ADS)

    Patton, H.; Hubbard, A.; Bradwell, T.; Glasser, N. F.; Hambrey, M. J.; Clark, C. D.

    2013-12-01

    Understanding the retreat behaviour of past marine-based ice sheets provides vital context for accurate assessments of the present stability and long-term response of contemporary polar ice sheets to climate and oceanic warming. Here new multibeam swath bathymetry data and sedimentological analysis are combined with high resolution ice-sheet modelling to reveal complex landform assemblages and process dynamics associated with deglaciation of the Celtic ice sheet within the Irish Sea Basin. Our reconstruction indicates a non-linear relationship between the rapidly receding Irish Sea Ice Stream and the retreat of outlet glaciers draining the adjacent, terrestrially based ice cap centred over Wales. Retreat of Welsh ice was episodic; superimposed over low-order oscillations of its margin are asynchronous outlet readvances driven by catchment-wide mass balance variations that are amplified through migration of the ice cap's main ice divide. Formation of large, linear ridges which extend at least 12.5 km offshore (locally known as sarns) and which dominate the regional bathymetry are attributed to repeated frontal and medial morainic deposition associated with the readvancing phases of these outlet glaciers. Our study provides new insight into ice-sheet extent, dynamics and non-linear retreat across a major palaeo-ice stream confluence zone, and has ramifications for the interpretation of recent fluctuations observed by satellites over short timescales across marine sectors of the Greenland and Antarctic ice sheets.

  17. A Century of Retreat at Portage Glacier, South-Central Alaska

    USGS Publications Warehouse

    Kennedy, Ben W.; Trabant, Dennis C.; Mayo, Lawrence R.

    2006-01-01

    Introduction: The Portage Glacier, in south-central Alaska, is viewed by thousands of visitors annually who come to the U.S. Forest Service Begich, Boggs Visitor Center located on the road system between Anchorage and Whittier, Alaska. During the past century, the terminus of the glacier has retreated nearly 5 kilometers to its present location (fig. 1). Like other glaciers that terminate in water, such as Columbia Glacier near Valdez or Mendenhall Glacier near Juneau, Portage Glacier has experienced accelerated retreats in recent decades that likely were initially triggered by climate change begun at the end of the Little Ice Age in the mid-1800s and subsequently controlled in recent history primarily by calving of the glacier terminus. Photographic records of the terminus covering 1914 until present day track the patterns of retreat. These data, coupled with USGS climate information collected from the southern end of the ice field, provide insight to the patterns of retreat that might be observed in the future.

  18. The Role of Adherence and Retreatment in De Novo Emergence of MDR-TB

    PubMed Central

    Cadosch, Dominique; Abel zur Wiesch, Pia; Kouyos, Roger; Bonhoeffer, Sebastian

    2016-01-01

    Treatment failure after therapy of pulmonary tuberculosis (TB) infections is an important challenge, especially when it coincides with de novo emergence of multi-drug-resistant TB (MDR-TB). We seek to explore possible causes why MDR-TB has been found to occur much more often in patients with a history of previous treatment. We develop a mathematical model of the replication of Mycobacterium tuberculosis within a patient reflecting the compartments of macrophages, granulomas, and open cavities as well as parameterizing the effects of drugs on the pathogen dynamics in these compartments. We use this model to study the influence of patient adherence to therapy and of common retreatment regimens on treatment outcome. As expected, the simulations show that treatment success increases with increasing adherence. However, treatment occasionally fails even under perfect adherence due to interpatient variability in pharmacological parameters. The risk of generating MDR de novo is highest between 40% and 80% adherence. Importantly, our simulations highlight the double-edged effect of retreatment: On the one hand, the recommended retreatment regimen increases the overall success rate compared to re-treating with the initial regimen. On the other hand, it increases the probability to accumulate more resistant genotypes. We conclude that treatment adherence is a key factor for a positive outcome, and that screening for resistant strains is advisable after treatment failure or relapse. PMID:26967493

  19. Root canal retreatment using reciprocating and continuous rotary nickel-titanium instruments

    PubMed Central

    de Souza, Patricia Fonseca; Oliveira Goncalves, Leonardo Cantanhede; Franco Marques, Andre Augusto; Sponchiado Junior, Emilio Carlos; Roberti Garcia, Lucas da Fonseca; de Carvalho, Fredson Marcio Acris

    2015-01-01

    Objective: The complete filling material removal during endodontic retreatment is a clinical procedure difficult to achieve. The aim of this study was to evaluate the efficacy of reciprocating and continuous rotary nickel-titanium instruments used in root canal retreatment. Materials and Methods: Forty freshly extracted human premolars were cleaned and shaped by the crown-down technique, followed by filling by the lateral compaction technique. The teeth were randomly separated into two groups (n = 20), according to the system used for filling material removal: G1 - Reciproc and G2 - ProTaper Universal Retreatment System. The teeth were photographed under operating microscope at ×8 magnification; and the total area of the root canal and remaining filling material were quantified. Results: No statistically significant difference (P > 0.05) in residual filling material was observed between groups; however, the time required for filling removal was significantly shorter for Reciproc system (P < 0.05). Conclusions: It was observed remaining filling material in all teeth, irrespective of the system used; however, root canal retreatment was faster when reciprocating motion was used. PMID:26038656

  20. Evolving force balance at Columbia Glacier, Alaska, during its rapid retreat

    USGS Publications Warehouse

    O'Neel, S.; Pfeffer, W.T.; Krimmel, R.; Meier, M.

    2005-01-01

    Changes in driving and resistive stresses play an essential role in governing the buoyancy forces that are important controls on the speed and irreversibility of tidewater glacier retreats. We describe changes in geometry, velocity, and strain rate and present a top-down force balance analysis performed over the lower reach of Columbia Glacier. Our analysis uses new measurements and estimates of basal topography and photogrammetric surface velocity measurements made between 1977 and 2001, while assuming depth-independent strain. Sensitivity tests show that the method is robust and insensitive to small changes in the calculation parameters. Spatial distributions of ice speed show little correspondence with driving stress. Instead, spatial patterns of ice speed exhibit a nonlinear correspondence with basal drag. Primary resistance to flow comes from basal drag, but lateral drag becomes increasingly more important throughout the retreat, which may account for observed increases in speed. Maximum basal drag is always located in a prominent constriction located ~12 km upstream from the preretreat terminus. Once the terminus retreated into deep water off the terminal moraine marking the modern maximum extent, the upstream location of this maximum basal drag helped to promote thinning and decrease effective pressure in the lower region by limiting replenishing ice flow from upstream. An increase in both ice velocity and calving resulted, initiating what appears to be an irreversible retreat. Copyright 2005 by the American Geophysical Union.

  1. Stepwise tailward retreat of magnetic reconnection: THEMIS observations of an auroral substorm

    NASA Astrophysics Data System (ADS)

    Ieda, A.; Nishimura, Y.; Miyashita, Y.; Angelopoulos, V.; Runov, A.; Nagai, T.; Frey, H. U.; Fairfield, D. H.; Slavin, J. A.; Vanhamäki, H.; Uchino, H.; Fujii, R.; Miyoshi, Y.; Machida, S.

    2016-05-01

    Auroral stepwise poleward expansions were clarified by investigating a multiple-onset substorm that occurred on 27 February 2009. Five successive auroral brightenings were identified in all-sky images, occurring at approximately 10 min intervals. The first brightening was a faint precursor. The second brightening had a wide longitude; thus, it represented the Akasofu substorm onset. Other brightenings expanded poleward; thus, they were interpreted to be auroral breakups. These breakups occurred stepwise; that is, later breakups were initiated at higher latitudes. Corresponding reconnection signatures were studied using Time History of Events and Macroscale Interactions during Substorms (THEMIS) satellite observations between 8 and 24 RE down the magnetotail. The Akasofu substorm onset was not accompanied by a clear reconnection signature in the tail. In contrast, the three subsequent auroral breakups occurred simultaneously (within a few minutes) with three successive fast flows at 24 RE; thus, these were interpreted to be associated with impulsive reconnection episodes. These three fast flows consisted of a tailward flow and two subsequent earthward flows. The flow reversal at the second breakup indicated that a tailward retreat of the near-Earth reconnection site occurred during the substorm expansion phase. In addition, the earthward flow at the third breakup was consistent with the classic tailward retreat near the end of the expansion phase; therefore, the tailward retreat is likely to have occurred in a stepwise manner. We interpreted the stepwise characteristics of the tailward retreat and poleward expansion to be potentially associated by a stepwise magnetic flux pileup.

  2. A Bayesian Approach to Forecasting Storm-induced Coastal Cliff Retreat

    NASA Astrophysics Data System (ADS)

    Hapke, C. J.; Plant, N. G.

    2009-12-01

    Existing models that are used to forecast coastal cliff erosion are typically focused on long-term response to sea-level rise, and include approaches such as a modified Bruun Rule or empirical models based on historical water level data. These methods provide solely deterministic predictions and have difficulty accounting for the spatial and temporal variability of cliff retreat processes. Such models also do not translate well to short-term or storm-induced forecasting, in which event-based cliff failure is episodic and does not necessarily respond instantaneously to forcing conditions. Cliff response may also depend on the influence of previous events. A Bayesian approach is applicable to both short-term (a single storm or series of storms) and longer-term (sea-level rise) hazard forecasting because it can take advantage of correlations between key variables that influence the variations in cliff-retreat processes including prior behavior, geometry and forcing parameters. This study uses a Bayesian network to evaluate the spatial distribution of short-term cliff retreat along a ~50 km stretch of coast in Southern California. Prior behavior is defined in the model using long-term (70-yr) cliff retreat rates. The geometry, or initial state, inputs include cliff slope and height, and a descriptor of material strength. The model is forced using wave impact hours determined by calculating the number of hours waves reached the cliff base elevation during the study period. Inputs for this parameter include wave and tide data from a local buoy, beach slope and cliff base elevation. The goal of the study is to assess the ability of a Bayesian model to predict the probability and spatial distribution of coastal cliff retreat from storm events. In order to develop a confirmable model, a three-year study period was used and was assumed to represent an adequate time period over which to capture storm conditions that resulted in measureable cliff response. The performance and

  3. 14 CFR 23.1389 - Position light distribution and intensities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... intensities in the horizontal plane, minimum intensities in any vertical plane, and maximum intensities in...) Intensities in the horizontal plane. Each intensity in the horizontal plane (the plane containing the longitudinal axis of the airplane and perpendicular to the plane of symmetry of the airplane) must equal...

  4. 14 CFR 23.1389 - Position light distribution and intensities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... intensities in the horizontal plane, minimum intensities in any vertical plane, and maximum intensities in...) Intensities in the horizontal plane. Each intensity in the horizontal plane (the plane containing the longitudinal axis of the airplane and perpendicular to the plane of symmetry of the airplane) must equal...

  5. A chronology for the retreat of the Irish Sea Ice-Stream using Bayesian modelling techniques

    NASA Astrophysics Data System (ADS)

    Thrasher, I. M.; Chiverrell, R. C.; Thomas, G. S. P.; Mauz, B.; Lang, A.

    2009-04-01

    During Marine Isotope Stage (MIS) 2 the Irish Sea Basin was occupied by the Irish Sea Ice-Stream (ISIS), a major outlet for ice which had accumulated in the British and Irish Ice Sheet (BIIS). The flow dynamics and flow phasing of this portion of the BIIS during maximum extent, the Last Glacial Maximum (LGM), and subsequent retreat are poorly understood due to a lack of chronological control. To improve understanding of the timing of maximum ice-stream extent and subsequent retreat, we have compiled the available chronological data for deposits associated with this phase of glaciation. These chronological data were arranged in an expected order using the geomorphological, stratigraphical and sedimentological field evidence. The relative order model broadly comprised a younging sequence from before the advance to LGM limits through subsequent retreat stages. Bayesian modelling techniques were used to evaluate the conformability of this pseudo-stratigraphical relative order model. Lack of conformity in the relative order model either implied problems with individual age determinations or that the relative order of events within the model is flawed, and in both cases the problems required explanation. The relative order model contained 52 age determinations for various phases of ice advance and retreat. Bayesian analysis showed that the relative order model, constructed with information provided by stratigraphical, geomorphological and geographical evidence was conformable with the existing chronology. The incorporation of prior information within the Bayesian framework enabled the refining of probability-based age estimates for the advance and retreat history of the ISIS. The expansion of ISIS to the maximum extent advancing across southern Ireland and into the Celtic Sea appears constrained to between 24.2-22.1 cal. kyr BP. Retreat stage ice-marginal positions are constrained to between 23.9-21.4 cal. kyr BP in Co. Wexford, south-eastern Ireland and between 23

  6. Repeated large-scale retreat and advance of Totten Glacier indicated by inland bed erosion.

    PubMed

    Aitken, A R A; Roberts, J L; van Ommen, T D; Young, D A; Golledge, N R; Greenbaum, J S; Blankenship, D D; Siegert, M J

    2016-05-19

    Climate variations cause ice sheets to retreat and advance, raising or lowering sea level by metres to decametres. The basic relationship is unambiguous, but the timing, magnitude and sources of sea-level change remain unclear; in particular, the contribution of the East Antarctic Ice Sheet (EAIS) is ill defined, restricting our appreciation of potential future change. Several lines of evidence suggest possible collapse of the Totten Glacier into interior basins during past warm periods, most notably the Pliocene epoch, causing several metres of sea-level rise. However, the structure and long-term evolution of the ice sheet in this region have been understood insufficiently to constrain past ice-sheet extents. Here we show that deep ice-sheet erosion-enough to expose basement rocks-has occurred in two regions: the head of the Totten Glacier, within 150 kilometres of today's grounding line; and deep within the Sabrina Subglacial Basin, 350-550 kilometres from this grounding line. Our results, based on ICECAP aerogeophysical data, demarcate the marginal zones of two distinct quasi-stable EAIS configurations, corresponding to the 'modern-scale' ice sheet (with a marginal zone near the present ice-sheet margin) and the retreated ice sheet (with the marginal zone located far inland). The transitional region of 200-250 kilometres in width is less eroded, suggesting shorter-lived exposure to eroding conditions during repeated retreat-advance events, which are probably driven by ocean-forced instabilities. Representative ice-sheet models indicate that the global sea-level increase resulting from retreat in this sector can be up to 0.9 metres in the modern-scale configuration, and exceeds 2 metres in the retreated configuration. PMID:27193684

  7. Cytotoxic effect of the debris apically extruded during three different retreatment procedures.

    PubMed

    Silva, Emmanuel J N L; Brito, Mônica E; Ferreira, Vivian D; Belladonna, Felipe G; Neves, Aline A; Senna, Plinio M; De-Deus, Gustavo

    2016-01-01

    We evaluated the cytotoxic effects of the debris apically extruded during root canal retreatment on primary human osteoblast (HOb) cells in vitro. TNF-α and IL-1β levels were also measured. We examined three different techniques: conventional hand-files, and Mtwo and Reciproc retreatments. Filled mandibular incisors were prepared for a cytotoxicity assay in an experimental root model. The material was divided into three groups according to the technique used. Ten teeth were used as control. HOb cells were exposed to the extruded content and cytotoxicity was evaluated using the MTT test (assessing cell metabolic activity). TNF-α and IL-1β production was also analyzed using enzyme-linked immunosorbent assay. Then, all the teeth were radiographed and the residual filling material was quantified. Data were subjected to analysis of variance (ANOVA) and Tukey's test (P < 0.05). The conventional hand-file technique was significantly more cytotoxic than the other methods (P < 0.05). Reciproc was less cytotoxic than Mtwo retreatment (P < 0.05). All endodontic retreatment techniques led to a significant upregulation of IL-1β levels (P < 0.05). However, only the conventional hand-file technique caused a significant increase in TNF-α levels (P < 0.05). Root-filling removal did not affect the levels of these proteins (P > 0.05). The Reciproc system required less time than the other two methods to remove the root-filling materials (P < 0.01). The endodontic retreatment with Reciproc was the least cytotoxic and the least time-consuming method of gutta-percha and sealer removal. (J Oral Sci 58, 211-217, 2016). PMID:27349542

  8. Diachronous seawater retreat from the southwestern margin of the Tarim Basin in the late Eocene

    NASA Astrophysics Data System (ADS)

    Sun, Jimin; Windley, Brian F.; Zhang, Zhiliang; Fu, Bihong; Li, Shihu

    2016-02-01

    In contrast to the present hyper-arid inland basin surrounded by the high mountains of Central Asia, the western Tarim Basin was once connected with the Tajik Basin at least in the late Eocene, when an epicontinental sea extended from the western Tarim Basin to Europe. Western Tarim is a key site for studying the retreat of seawater, which was likely caused by the northward indentation of the Pamir arc and facilitated by the climatic cooling and eustatic sea level change in the Cenozoic. Here we present a new magnetostratigraphic record from the Tarim Basin that provides evidence of diachronous seawater retreat from its southwestern margin. We studied about 1360 m of well-exposed Eocene-Oligocene strata at Keliyang in the folded foreland of the West Kunlun orogen. Until now, the age of the strata has only been minimally constrained by the presence of late mid-Eocene marine fossils. Our biostratigraphic and magnetostratigraphic results demonstrate that the age of the sedimentary sequence ranges from ∼46 Ma to ∼26 Ma (mid-Eocene to late-Oligocene) and the seawater retreat at Keliyang took place at ∼40 Ma. Considering the stepwise northward indentation and uplift of the Pamir orogen, together with the other previous results, we propose that seawater retreat from the southwestern margin of the Tarim Basin was diachronous in the late Eocene ranging from 47 Ma to 40 Ma. The regional indentation, uplift and erosion of the Pamir orogen played the dominant and important role in controlling the seawater retreat from the southwestern margin of the Tarim Basin.

  9. Restoration of longitudinal images.

    PubMed

    Hu, Y; Frieden, B R

    1988-01-15

    In this paper, a method of restoring longitudinal images is developed. By using the transfer function for longitudinal objects, and inverse filtering, a longitudinal image may be restored. The Fourier theory and sampling theorems for transverse images cannot be used directly in the longitudinal case. A modification and reasonable approximation are introduced. We have numerically established a necessary relationship between just-resolved longitudinal separation (after inverse filtering), noise level, and the taking conditions of object distance and lens diameter. An empirical formula is also found to well-fit the computed results. This formula may be of use for designing optical systems which are to image longitudinal details, such as in robotics or microscopy. PMID:20523607

  10. Reasons for Retreatment of Amalgam and Composite Restorations among the Patients Referring to Tabriz Faculty of Dentistry

    PubMed Central

    Kimyai, Soodabeh; Mehdipour, Masomeh; Savadi Oskoee, Siavash; Alizadeh Oskoee, Parnian; Abbaszadeh, Armin

    2007-01-01

    Background and aims Retreatment of existing restorations not only requires a lot of money and time but also there is a danger of weakening tooth structure and irritating the pulp. Since awareness of the reasons for the retreatment of teeth will save the teeth from possible future failure, the aim of this study was to assess the reasons for retreatment of amalgam and composite restorations in patients referring to Tabriz Faculty of Dentistry. Materials and methods In this descriptive study, the subjects had previously received an amalgam or a composite restoration in the Operative Department by dental students and were judged to need retreatment in their second visit. A total of 300 defective teeth were selected by simple random sampling method. The data was collected through examination and questionnaires and analyzed using chi-square test. Results There was a statistically significant association between the type of the restorative material and the reason for retreatment (p=0.001). Conclusion Although the reasons for the retreatment of amalgam and composite restorations were different, recurrent caries was the main reason for the retreatment for both restorative materials. PMID:23277830

  11. Habitat Selection in a Rocky Landscape: Experimentally Decoupling the Influence of Retreat Site Attributes from That of Landscape Features

    PubMed Central

    Croak, Benjamin M.; Pike, David A.; Webb, Jonathan K.; Shine, Richard

    2012-01-01

    Organisms selecting retreat sites may evaluate not only the quality of the specific shelter, but also the proximity of that site to resources in the surrounding area. Distinguishing between habitat selection at these two spatial scales is complicated by co-variation among microhabitat factors (i.e., the attributes of individual retreat sites often correlate with their proximity to landscape features). Disentangling this co-variation may facilitate the restoration or conservation of threatened systems. To experimentally examine the role of landscape attributes in determining retreat-site quality for saxicolous ectotherms, we deployed 198 identical artificial rocks in open (sun-exposed) sites on sandstone outcrops in southeastern Australia, and recorded faunal usage of those retreat sites over the next 29 months. Several landscape-scale attributes were associated with occupancy of experimental rocks, but different features were important for different species. For example, endangered broad-headed snakes (Hoplocephalus bungaroides) preferred retreat sites close to cliff edges, flat rock spiders (Hemicloea major) preferred small outcrops, and velvet geckos (Oedura lesueurii) preferred rocks close to the cliff edge with higher-than-average sun exposure. Standardized retreat sites can provide robust experimental data on the effects of landscape-scale attributes on retreat site selection, revealing interspecific divergences among sympatric taxa that use similar habitats. PMID:22701592

  12. Longitudinal impedance of RHIC

    SciTech Connect

    Blaskiewicz, M.; Brennan, J. M.; Mernick, K.

    2015-05-03

    The longitudinal impedance of the two RHIC rings has been measured using the effect of potential well distortion on longitudinal Schottky measurements. For the blue RHIC ring Im(Z/n) = 1.5±0.2Ω. For the yellow ring Im(Z/n) = 5.4±1Ω.

  13. Longitudinal Multistage Testing

    ERIC Educational Resources Information Center

    Pohl, Steffi

    2013-01-01

    This article introduces longitudinal multistage testing (lMST), a special form of multistage testing (MST), as a method for adaptive testing in longitudinal large-scale studies. In lMST designs, test forms of different difficulty levels are used, whereas the values on a pretest determine the routing to these test forms. Since lMST allows for…

  14. Re-treatment of relapsed Paget's disease of bone with zoledronic acid: results from an open-label study.

    PubMed

    Reid, Ian R; Brown, Jacques P; Levitt, Naomi; Román Ivorra, José A; Bachiller-Corral, Javier; Ross, Ian L; Su, Guoqin; Antunez-Flores, Oscar; Aftring, R Paul

    2013-01-01

    Six patients from the phase 3 trials of zoledronic acid in Paget's disease, who had received zoledronic acid initially and had subsequently relapsed, were entered into an open re-treatment study. Following re-treatment, each patient reached similar absolute nadirs of serum alkaline phosphatase to those recorded after their first dose. No significant adverse events were reported. It is concluded that, while re-treatment of Paget's disease with zoledronic acid is rarely needed, it is safe and effective, with no evidence of treatment resistance based on this small cohort. PMID:24422139

  15. Identifying potential seasonal and historical drivers of marine-terminating glacier retreat in Disko and Uummannaq Bays, West Greenland

    NASA Astrophysics Data System (ADS)

    York, A.; Frey, K. E.; Das, S. B.

    2015-12-01

    The variability in outlet glacier termini positions is an important indicator of overall glacier health and the net effects of ice-ocean-atmosphere interactions. Glacier margins fluctuate on both seasonal and interannual time scales and satellite imagery provides a critical spatially- and temporally-extensive resource for monitoring glacier behavior. Outlet glaciers have generally been retreating globally over recent decades, but the magnitude of seasonal variation, overall retreat, and foremost drivers have proven unique to each glacier. The outlet glaciers in central West Greenland are generally experiencing the same regional atmospheric forcing, yet previous studies have shown varying magnitudes of retreat over the last forty years. In this study, we utilize Landsat imagery between the years 1985 and 2014 to digitize a time series of glacier front positions of 18 marine-terminating outlet glaciers in the Disko and Uummannaq Bay regions of West Greenland. We examine potential drivers of trends in outlet glacier retreat through satellite observations of adjacent sea ice concentrations and sea surface temperatures. Additionally, reanalysis data and long-term automatic weather station measurements are investigated to contextualize the role of atmospheric drivers at both a regional and local scale. Results indicate retreat of all glaciers in the region over the study period and no indication of a south to north trend in magnitude of retreat on either a seasonal or long-term scale. The 11 glaciers in Uummannaq Bay retreated between 25 m and 3.5 km, an average of 1.22 ± 1.20 km over the entire study period. The retreat of 7 glaciers in Disko Bay ranged from 181 m to 2.3 km, an average of 1.0 ± 0.78 km over the period. Although the mean terminus retreat rate between the two bays is comparable, there remains a wide range of total retreat amounts among the glaciers. We investigate the degree of seasonal variation in terminus position as an indicator of longer

  16. The Tenth Annual Ion Channel Retreat, Vancouver, Canada, June 25–27, 2012

    PubMed Central

    Kimlicka, Lynn; Liang, Sophia; Brugger, Saranna; Liang, Dong

    2013-01-01

    Abstract Ten years after Aurora Biomed (Vancouver, British Columbia, Canada) hosted the inaugural Ion Channel Retreat, this event is recognized as a leading conference for ion channel researchers. Held annually in Vancouver, this meeting consistently provides an outlet for researchers to share their findings while learning about new concepts, methods, and technologies. Researchers use this forum to discuss and debate a spectrum of topics from ion channel research and technology to drug discovery and safety. The Retreat covered key subjects in the ion channel industry, including ion channels as disease targets, transient receptor protein channels as pain and disease targets, ion channels as pain targets, ion channel structure and function, ion channel screening technologies, cardiac safety and toxicology, and cardiac function and pharmacology. PMID:23679851

  17. Glacial Retreat and Associated Glacial Lake Hazards in the High Tien Shan

    NASA Astrophysics Data System (ADS)

    Smith, T. T.

    2013-12-01

    A number of studies have identified glacial retreat throughout the greater Himalayan region over the past few decades, but the Karakorum region remains an anomaly with large stagnating or advancing glaciers. The glacial behavior in the Tien Shan is still unclear, as few studies have investigated mass balances in the region. This study focuses on the highest peaks of the Tien Shan mountain range, in the region of Jengish Chokusu along the Kyrgyzstan-China-Kazakhstan border. In a first step, a 30-year time series of Landsat imagery (n=27) and ASTER imagery (n=10) was developed to track glacial growth and retreat in the region. Using a combination of spectral and topographic information, glacial outlines are automatically delineated. As several important glaciers in the study region contain medium to high levels of debris cover, our algorithm also improves upon current methods of detecting debris-covered glaciers by using topography, distance weighting methods, river networks, and additional spectral data. Linked to glacial retreat are glacial lake outburst floods (GLOFs) that have become increasingly common in High Mountain Asia over the last few decades. As glaciers retreat, their melt water is often trapped by weakly bonded moraines. These moraines have been known to fail due to overtopping caused by surge waves created by avalanches, rockslides, or glacial calving. A suite of studies throughout High Mountain Asia have used remotely-sensed data to monitor the formation and growth of glacial lakes. In a second step of the work, lake-area changes over the past 15 years were tracked monthly and seasonally using dense Landsat/ASTER coverage (n=30) with an automatic procedure based on spectral and topographic information. Previous work has identified GLOFs as a significant process for infrastructural damage in the southern Tien Shan/northern Pamir, as well as in the better studied Himalaya region. Lake identification and quantification of lake-growth rates is a valuable

  18. A Subgrid-Scale Parameterization for Calving-Front Advance and Retreat

    NASA Astrophysics Data System (ADS)

    Albrecht, Torsten

    2010-05-01

    Floating ice shelves fringing most of Antarctica play a key for the flow of ice into the ocean and thereby for global sea level rise. Calving processes at the ice front are highly complex and are often neglected in numerical ice sheet models. Observed accelerated ice discharge after abrupt ice shelf retreat proofs that this is not a viable approach. In order to be able to take ice shelf dynamics into account we have implemented a number of processes into the Potsdam Parallel Ice Sheet Model (PISM-PIK). We present a newly developed subgrid-scale parameterization for calving-front advance and retreat which allows the introduction of stress boundary conditions on the ice-ocean front and thereby a proper computation of the stress and strain field along the calving front. With these improvements we compare different calving rate approaches for different realistic ice shelf geometries (Albrecht et al., J Glac., in prep.).

  19. Retreatment of recurrent carcinoma of the head and neck by afterloading interstitial 192Ir implant

    SciTech Connect

    Emami, B.; Marks, J.E.

    1983-10-01

    From January 1975 to December 1980, 25 patients with persistent or recurrent carcinomas of the head and neck were retreated for palliation at the Division of Radiation Oncology, Mallinckrodt Institute of Radiology. These patients had all undergone extensive previous treatment by surgery and/or radiation. All were retreated with 192Ir interstitial implant with or without external radiation and/or surgical excision. Of 25 patients, 13 had complete response (CR) and 6 had partial response for a follow-up period of 1 to 7 years. Of 13 patients with CR, 6 are alive with no evidence of disease (NED) and two died NED. Detailed results are presented and the new strategy for such patients is discussed.

  20. A Case of Successful Retreatment of a Maxillary Lateral Incisor with a Supernumerary Root

    PubMed Central

    Aminsobhani, Mohsen

    2015-01-01

    Knowledge about the morphology of the root canal system is a pre-requisite for achieving a successful outcome in root canal treatment. In this report, a patient with a maxillary lateral incisor which had previously undergone orthograde endodontic retreatment for two times is discussed. The tooth had been misdiagnosed with a palatal groove or a root fracture, its prognosis had been determined to be poor and extraction was advised by a practitioner. During our evaluation, an unrecognized supernumerary root and root canal were detected and the tooth was maintained successfully with orthograde endodontic retreatment. The use of cone beam computed tomography (CBCT) and magnification were of significance in the treatment process of this case.

  1. Experimental observations on the retreat of non-cohesive river banks

    NASA Astrophysics Data System (ADS)

    Solari, L.; Nardi, L.; Rinaldi, M.

    2009-12-01

    The topic of bank retreat is of particular relevance in the hydro-morphodynamic models devoted to study the planform evolution of rivers. This notwithstanding, in many models bank retreat is evaluated through over-simplified algorithms based, for instance, on the knowledge of the near bank flow velocity and some erodibility coefficient which does not have an explicit physical meaning. In the literature, the majority of studies on the modelling of bank processes are about cohesive banks composed by fine sediments; the retreat of these type of banks has been related to the stability and mass wasting processes through algorithms originally developed in the geotechnical field. In gravel-bed rivers, banks are often composite with a basal layer of gravel and an upper cohesive layer, or, sometime, completely composed by granular, relatively coarse sediments (gravel and cobbles). The mechanisms of bank retreat in relatively coarse riverbanks (mainly composed by gravel) represent an area that needs further investigation, as numerous physical mechanisms are still not understood. This research aims at gaining a better comprehension of the basic processes occurring in relatively coarse bank sediments; in particular, it focuses on the mass instability mechanisms due to the oscillations of free surface water level. The fluvial erosion of the streambank due to the boundary shear stresses is not taken into account. A physical model of a bank composed by granular relatively coarse sediments has been reproduced in a static tank. The main characteristics of the bank; such as geometry, sediment distribution and degree of packing, were set on the basis of the field observations of the riverbanks in the Cecina River (Tuscany). A first set of experiments simulating the behavior of the bank during a hydrograph has been carried out. Several sensors inserted into the bank allow monitoring the seepage flow and pore water pressures. Preliminary results are here reported, with a discussion of

  2. Processes controlling the retreat of the Isles Dernieres, a Louisiana barrier-island chain

    USGS Publications Warehouse

    Dingler, John R.; Reiss, Thomas E.

    1991-01-01

    The Isles Dernieres is a low-lying, transgressive barrier-island chain situated about 150 km west of the modern Mississippi delta. Much of the Isles Dernieres consists of highly dissected salt-marsh muds that lie at or slightly above sea level and are covered by a veneer of sand along the shoreline facing the Gulf of Mexico. Maximum berm elevations are generally less than 1.5 m above mean sea level. Since the mid-1800s, the initial island has been fragmented into four islands, and the beach face has retreated landward at a rate of more than 10 m/yr. The dominant processes controlling degradation of the chain are cold fronts that pass through the area several times each year and occasional hurricanes. Beach surveys over a 2-year period on the Isles Dernieres document irreversible beach-face retreat in conjunction with multiple cold fronts and one major hurricane (Gilbert). Although both the hurricane and the cold fronts caused the island to erode, the erosional patterns of the two storm types differed from each other. During the two years, over 60 cold fronts collectively caused about 37 m of beach-face retreat, whereas Gilbert itself produced more than 40 m of retreat. A major difference between the two storm types was in the percentage of washover sand produced by each. Commonly, the cold fronts did not create enough of a storm surge to overtop the berm, so most of the material removed from the beach face must have moved offshore or alongshore. Gilbert, in contrast, inundated the study site, and essentially all the sand removed from the beach face moved to the backshore.

  3. A complex deglacial retreat history of the Anvers Island Trough paleo-ice stream

    NASA Astrophysics Data System (ADS)

    Shevenell, A.; Ishman, S. E.; Domack, E. W.; Leventer, A.; Rosenheim, B. E.; Vadman, K. J.

    2015-12-01

    Marine-terminating ice regulates the mass balance and stability of Antarctica's ice sheets and, ultimately, global sea level. However, predictions of future ice sheet response to climate change are limited by short observational time-series and the complexity of associated forcings and feedbacks. Here, we present new chronologic and multiproxy data from 7 marine sediment records from the outer to inner shelf down the axis of the Anvers Island Trough and into Palmer Deep that better constrain the timing and rate of ice retreat and improve understanding of the mechanisms driving deglaciation of this hypothesized paleo-ice stream. The retreat chronology is based on 16 CaCO3 (foraminifer and mollusk) and 45 ramped pyrolysis (acid-insoluble organic matter) AMS 14C dates. Radiocarbon dates from the laminated diatom ooze and mud facies immediately above the glacial diamicton indicate that deglaciation of the mid-Anvers Island Trough post-dated the Palmer Deep deglaciation by ~2000 uncorrected 14C years and that collapse of the mid-shelf system was rapid, if not instantaneous. The laminated facies, present throughout the suite of cores, is consistent with the calving bay reentrant model for deglaciation. However, this facies is limited (~15 couplets) on the mid-shelf and expanded (~127 couplets) on the inner-shelf, suggesting regional differences in calving bay duration. Planktic and benthic foraminifer isotopes, together with foraminifer and diatom assemblages, and biogeochemical data provide evidence for the presence of warmer nutrient-rich modified Circumpolar Deep Water throughout the Anvers Island Trough during deglaciation. The observed retreat complexity may relate to a hypothesized mid-shelf ice-dome system and requires additional geological and geophysical data to understand ice retreat patterns south and west of Palmer Deep. Such data will provide important new constraints for ice sheet models.

  4. Pattern and timing of retreat of the last British-Irish Ice Sheet

    NASA Astrophysics Data System (ADS)

    Clark, C. D.; Hughes, A. L.; Greenwood, S. L.

    2009-12-01

    Ice sheets leave behind a fragmentary record of their activity, which is then incompletely sampled by geoscientists, and a small fraction of this evidence is subjected to geochronometric dating, some of which yields useful timing constraints on the ice sheet. We thus have an incomplete knowledge of the time-space envelope of ice sheet extent and yet we possess a strong desire to link any changes to known or posited climate fluctuations. If we are to reduce conjecture, speculation and wishful event-matching (‘my moraine records a Heinrich event but your doesn’t!’), clearly the magnitude of the task demands a systematic and cautious approach. For Britain and Ireland there is a wealth of published evidence, maps and dates, that have never been systematically assembled to yield a dated retreat pattern for the ice sheet. In this paper we summarise new mapping of glacial landforms (especially moraines and meltwater channels), merge it with published work, and together, use the data (including drumlins, eskers and ice dammed lakes) to derive a pattern of retreat. We review and compile all known relevant dates for the region (> 400 examples) that constrain the timing of retreat. All data is held within a GIS, and is then manipulated to produce a best-estimate of the combined pattern and timing of retreat of the ice sheet. The data, method and results will be presented and it is emphasised that this is almost certainly not the complete picture, but provides a useful framework of what is known.

  5. Retreatment with aromatase inhibitor therapy in the management of granulosa cell tumor.

    PubMed

    Schwartz, Melissa; Huang, Gloria S

    2016-01-01

    •Over 90% of granulosa cell tumors have a FOXL2 mutation that contributes to aromatase upregulation.•Chemotherapy has demonstrated limited efficacy in the treatment of granulosa cell tumors.•A patient with recurrent granulosa cell tumor responded briefly to anastrazole treatment.•Retreatment with another aromatase inhibitor letrozole led to a durable response of 24 months. PMID:26937482

  6. Retreatment of a transfer patient with bialveolar protrusion with mini bone-plate anchorage.

    PubMed

    Bilodeau, John E

    2014-10-01

    A 40-year-old black woman, with pretorqued, preangulated appliances on the maxillary teeth, transferred with chief concerns of missing teeth and her orthodontic progress. She had bialveolar protrusion and edentulous areas in both the maxilla and the mandible. After records were made and her desires assessed, she was retreated with the extraction of 3 premolars. Her protrusion was reduced and all edentulous spaces were closed. The facial change was evident due to the reduction of the protrusion. PMID:25263153

  7. Past ice-sheet behaviour: retreat scenarios and changing controls in the Ross Sea, Antarctica

    NASA Astrophysics Data System (ADS)

    Halberstadt, Anna Ruth W.; Simkins, Lauren M.; Greenwood, Sarah L.; Anderson, John B.

    2016-05-01

    Studying the history of ice-sheet behaviour in the Ross Sea, Antarctica's largest drainage basin can improve our understanding of patterns and controls on marine-based ice-sheet dynamics and provide constraints for numerical ice-sheet models. Newly collected high-resolution multibeam bathymetry data, combined with two decades of legacy multibeam and seismic data, are used to map glacial landforms and reconstruct palaeo ice-sheet drainage. During the Last Glacial Maximum, grounded ice reached the continental shelf edge in the eastern but not western Ross Sea. Recessional geomorphic features in the western Ross Sea indicate virtually continuous back-stepping of the ice-sheet grounding line. In the eastern Ross Sea, well-preserved linear features and a lack of small-scale recessional landforms signify rapid lift-off of grounded ice from the bed. Physiography exerted a first-order control on regional ice behaviour, while sea floor geology played an important subsidiary role. Previously published deglacial scenarios for Ross Sea are based on low-spatial-resolution marine data or terrestrial observations; however, this study uses high-resolution basin-wide geomorphology to constrain grounding-line retreat on the continental shelf. Our analysis of retreat patterns suggests that (1) retreat from the western Ross Sea was complex due to strong physiographic controls on ice-sheet drainage; (2) retreat was asynchronous across the Ross Sea and between troughs; (3) the eastern Ross Sea largely deglaciated prior to the western Ross Sea following the formation of a large grounding-line embayment over Whales Deep; and (4) our glacial geomorphic reconstruction converges with recent numerical models that call for significant and complex East Antarctic ice sheet and West Antarctic ice sheet contributions to the ice flow in the Ross Sea.

  8. Repeated large-scale retreat and advance of Totten Glacier indicated by inland bed erosion

    NASA Astrophysics Data System (ADS)

    Aitken, A. R. A.; Roberts, J. L.; Ommen, T. D. Van; Young, D. A.; Golledge, N. R.; Greenbaum, J. S.; Blankenship, D. D.; Siegert, M. J.

    2016-05-01

    Climate variations cause ice sheets to retreat and advance, raising or lowering sea level by metres to decametres. The basic relationship is unambiguous, but the timing, magnitude and sources of sea-level change remain unclear; in particular, the contribution of the East Antarctic Ice Sheet (EAIS) is ill defined, restricting our appreciation of potential future change. Several lines of evidence suggest possible collapse of the Totten Glacier into interior basins during past warm periods, most notably the Pliocene epoch, causing several metres of sea-level rise. However, the structure and long-term evolution of the ice sheet in this region have been understood insufficiently to constrain past ice-sheet extents. Here we show that deep ice-sheet erosion—enough to expose basement rocks—has occurred in two regions: the head of the Totten Glacier, within 150 kilometres of today’s grounding line; and deep within the Sabrina Subglacial Basin, 350–550 kilometres from this grounding line. Our results, based on ICECAP aerogeophysical data, demarcate the marginal zones of two distinct quasi-stable EAIS configurations, corresponding to the ‘modern-scale’ ice sheet (with a marginal zone near the present ice-sheet margin) and the retreated ice sheet (with the marginal zone located far inland). The transitional region of 200–250 kilometres in width is less eroded, suggesting shorter-lived exposure to eroding conditions during repeated retreat–advance events, which are probably driven by ocean-forced instabilities. Representative ice-sheet models indicate that the global sea-level increase resulting from retreat in this sector can be up to 0.9 metres in the modern-scale configuration, and exceeds 2 metres in the retreated configuration.

  9. Micro-CT Evaluation of Root Filling Removal after Three Stages of Retreatment Procedure.

    PubMed

    Rosa, Ricardo Abreu da; Santini, Manuela Favarin; Cavenago, Bruno Cavalini; Pereira, Jefferson Ricardo; Duarte, Marco Antônio Húngaro; Só, Marcus Vinícius Reis

    2015-12-01

    The aim of this study was to quantify the residual filling material after filling removal, re-preparation with rotary or reciprocating files and passive ultrasonic irrigation (PUI). Twenty maxillary molars were prepared using ProTaper instruments up to F1. The teeth were filled with AH Plus and ProTaper gutta-percha points using the single-cone technique. Thereafter, the specimens were scanned using a micro-computed tomography system (Micro-CT #1). Then, the root canal filling was removed using ProTaper Retreatment files, and a new scan was performed (Micro-CT #2). The specimens were divided into two groups according to the instrument used for re-preparation: ProTaper rotary or WaveOne reciprocating files (Micro-CT #3). Finally, PUI was performed, and a new micro-CT scan was performed (Micro-CT #4). Intragroup and intergroup analyses were performed using Friedman and Dunn's post hoc test and the Kruskal-Wallis and Dunn post hoc tests, respectively. Palatal canal presented the highest volume of residual filling material in all stages of endodontic retreatment (p<0.05). The main reduction of filling volume was achieved after using ProTaper Retreament (p<0.05). The amount of remaining filling material after using ProTaper Retreatment was similar to that achieved with rotary and reciprocating files and after PUI (p>0.05). Rotary and reciprocating files achieved similar removal of the root canal filling (p>0.05). The greatest reduction in filling material was achieved after using ProTaper Retreatment files. Rotary and reciprocating instruments and PUI did not improve the removal of root canal filling materials. PMID:26963205

  10. Irregular tropical glacier retreat over the Holocene epoch driven by progressive warming.

    PubMed

    Jomelli, Vincent; Khodri, Myriam; Favier, Vincent; Brunstein, Daniel; Ledru, Marie-Pierre; Wagnon, Patrick; Blard, Pierre-Henri; Sicart, Jean-Emmanuel; Braucher, Régis; Grancher, Delphine; Bourlès, Didier Louis; Braconnot, Pascale; Vuille, Mathias

    2011-06-01

    The causes and timing of tropical glacier fluctuations during the Holocene epoch (10,000 years ago to present) are poorly understood. Yet constraining their sensitivity to changes in climate is important, as these glaciers are both sensitive indicators of climate change and serve as water reservoirs for highland regions. Studies have so far documented extra-tropical glacier fluctuations, but in the tropics, glacier-climate relationships are insufficiently understood. Here we present a (10)Be chronology for the past 11,000 years (11 kyr), using 57 moraines from the Bolivian Telata glacier (in the Cordillera Real mountain range). This chronology indicates that Telata glacier retreated irregularly. A rapid and strong melting from the maximum extent occurred from 10.8 ± 0.9 to 8.5 ± 0.4 kyr ago, followed by a slower retreat until the Little Ice Age, about 200 years ago. A dramatic increase in the rate of retreat occurred over the twentieth century. A glacier-climate model indicates that, relative to modern climate, annual mean temperature for the Telata glacier region was -3.3 ± 0.8 °C cooler at 11 kyr ago and remained -2.1 ± 0.8 °C cooler until the end of the Little Ice Age. We suggest that long-term warming of the eastern tropical Pacific and increased atmospheric temperature in response to enhanced austral summer insolation were the main drivers for the long-term Holocene retreat of glaciers in the southern tropics. PMID:21654802

  11. Projections of grounding line retreat in West Antarctica carried out with an adaptive mesh model

    NASA Astrophysics Data System (ADS)

    Cornford, Stephen; Payne, Antony; Martin, Daniel; Le Brocq, Anne

    2013-04-01

    Present and future sea level rise associated with mass loss from West Antarctica is typically attributed to marine glaciers retreating in response to a warming ocean. Warmer waters melt the floating ice shelves that restrain some, if not all, marine glaciers, and the glaciers themselves respond by speeding up. That leads to thinning and in turn grounding line retreat. Satellite observations indicate that Amundsen Sea Embayment and, in particular, Pine Island Glacier, are undergoing this kind of dynamic change today. Numerical models, however, struggle to reproduce the observed behavior because either high resolution or some other kind special treatment is required at the grounding line. We present 200-year projections of three major glacier systems of West Antarctica: those that drain into the Amundsen Sea , the Filchner-Ronne Ice Shelf and the Ross Ice shelf. We do so using the newly developed BISICLES ice­ sheet model, which employs adaptive ­mesh refinement to maintain sub-kilometer resolution close to the grounding line and coarser resolution elsewhere. Ice accumulation and ice­ shelf melt-rate are derived from a range of models of the Antarctic atmosphere and ocean forced by the SRES A1B and E1 scenarios. We find that a substantial proportion of the grounding line in West Antarctica retreats, however the total sea level rise is less than 50 mm by 2100, and less than 100 mm by 2200. The lion's share of the mass loss is attributed to Pine Island Glacier, while its immediate neighbor Thwaites Glacier does not retreat until the end of the simulations.

  12. Climate change and glacier retreat from 1955 to 2006 on Cilo Mountains, Southeast Anatolia, Turkey

    NASA Astrophysics Data System (ADS)

    Yeşilyurt, Serdar; Uǧur, Doǧan; Kılar, Hatice

    2013-04-01

    Alpine glaciers are amongst key indicators of global-scale climate changes because of their natural dynamics and quick response to global warming. Although there is vast number of studies on recent glaciers of the world, less attention has been paid to the glaciers of Turkey and the Middle East. In the present study, present glaciers of Cilo Mountains (4135 m) located in Southeast Anatolia, one of the most important recent glacier areas of Turkey, is dealt with within the context of the impacts of climatic changes on glaciers. Based on aerial photographs taken in 1955, 1968 and 1988 together with Quickbird satellite images taken in 2006, four main stages were examined using remote sensing and GIS technologies. The paleo-glacier cover of the Last Glacial age (most likely the Last Glacial Maximum) on the Cilo Range was about 100 km² in area as compared to the actual glaciers found in the three valley system around Uludoruk summit with an area of only 5.6 km². Actual glacier have retreated between 100 and 360 m in the period from 1955 to 2006. According to elevation, thickness-mass characteristics of the glaciers and geomorphic conditions of their cirques, retreat rates were found to be between 2 and 7 m/yr. The ages of young terminal moraines were also calculated on the basis of annual decline rates of these glaciers. Consequently, the oldest moraines should have probably been deposited between 1850 and 1870 matching end of the Little Ice Age. This age is compatible with the glacier retreat of the European Alps. We determined a warming trend both in summer temperatures and annual averages based on data from three meteorological stations located in the vicinity of this mountain area. Keywords: Cilo Mountains, actual glacier, glacier retreat, climate change, Little Ace Age, Turkey

  13. Millennial Rates of Sea Cliff Retreat Derived From Cosmogenic 10Be and Coastal Platform Morphology

    NASA Astrophysics Data System (ADS)

    Hurst, M. D.; Ellis, M. A.; Rood, D. H.

    2014-12-01

    Observation of cliff erosion are often limited to relatively short timescales (a few decades), which are within the timeframe of anthropogenic modification of the coast and may be shorter than the recurrence interval for erosion events. Here we present long-term (centennial-millennial) averaged rates of sea cliff retreat for chalk cliffs in SE England derived from cosmogenic isotopes and coastal morphology. We determine long-term rates of sea cliff erosion from 10Be measured from in situ flint samples collected from three transects across the coastal platform in East Sussex. A numerical model of 10Be accumulation on an evolving coastal profile allows estimation of cliff retreat rate averaged over several hundred years. The model accounts for variation in 10Be accumulation with tides and sea-level rise, and takes into account platform downwear and topographic shielding by adjacent cliffs. Additionally, we use high-resolution (1m) multibeam bathymetry to map the extent of the coastal platform based on the surface texture in order to infer the position of the coast at ~8 ka. The difference in position to the current coastline provides estimates of Holocene-averaged rates of cliff erosion for all chalk cliffed coastline in the region. Comparison to historic records of cliff retreat reveals key similarities and differences between long and short-term signals. In certain locations, there are significant discrepancies (either faster or slower) between historic records and long-term rates of retreat. Each type of discrepancy may be the result of human interaction with the coastal environment, whether that interaction is local or non-local, and it is worthwhile noting that sites of relatively low historic rates of erosion are likely subject to high-magnitude, low-frequency failure events that could have devastating effects on human lives and infrastructure in areas that are considered to be low risk.

  14. On optimal retreat distance for the equivalent source method-based nearfield acoustical holography.

    PubMed

    Bai, Mingsian R; Chen, Ching-Cheng; Lin, Jia-Hong

    2011-03-01

    As a basic form of the equivalent source method (ESM) that is used to nearfield acoustical holography (NAH) problems, discrete monopoles are utilized to represent the sound field of interest. When setting up the virtual source distribution, it is vital to maintain a "retreat distance" between the virtual sources and the actual source surface such that reconstruction would not suffer from singularity problems. However, one cannot increase the distance without bound because of the ill-posedness inherent in the reconstruction process with large distance. In prior research, 1-2 times lattice spacing, or the inter-element distance of microphones, is generally recommended as retreat distance in using the ESM-based NAH. While this rule has shown to yield good results in many cases, the optimal choice is a complicated issue that depends on frequency, geometry of the physical source, content of evanescent waves, distribution of sensors and virtual sources, etc. This paper deals about attaining the best compromise between the reconstruction errors induced by the point source singularity; the reconstruction ill-posedness is an interesting problem in its own right. The paper revisits this issue, with the aid of an optimization algorithm based on the golden section search and parabolic interpolation. Numerical simulations were conducted for a baffled planar piston source and a spherically baffled piston source. The results revealed that the retreat distance appropriate for the ESM ranged from 0.4 to 0.5 times the spacing for the planar piston, while from 0.8 to 1.7 times average spacing for the spherical piston. Experiments carried out for a vibrating aluminum plate also revealed that the retreat distance with 0.5 times the spacing yielded better reconstructed velocity than those with 1/20 and 1 times the spacing. PMID:21428505

  15. Abrupt intensification of ENSO forced by deglacial ice-sheet retreat in CCSM3

    NASA Astrophysics Data System (ADS)

    Lu, Zhengyao; Liu, Zhengyu; Zhu, Jiang

    2016-03-01

    The influence of ice-sheet retreat on the El Niño-Southern Oscillation (ENSO) variability is studied using a transient simulation in NCAR-CCSM3 forced only by variations in continental ice sheets during the last deglaciation. The most striking feature is an abrupt strengthening of ENSO (by ~25 %) at 14 thousand years before present (ka BP) in response to a significant retreat (an equivalent ~25 m sea-level rise) of the Laurentide ice sheet (LIS). This abrupt intensification of ENSO is caused mainly by a sudden weakening of the equatorial annual cycle through the nonlinear mechanism of frequency entrainment, rather than an increase in the coupled ocean-atmosphere instability. The weakened annual cycle corresponds to a reduced north-south cross-equatorial annual mean SST contrast in the eastern Pacific. This reduced interhemispheric SST gradient—significant cooling north of the equator—is forced predominantly by an anomalous easterly from an abrupt polarward shift of the jet stream in the Northern Hemisphere, which extends to the northeastern tropical Pacific Ocean surface and is reinforced by the wind-evaporation-SST feedback then propagates equatorward; it could also be contributed by a fast sea-ice expansion and a consequent cooling in the North Pacific and North Atlantic that is induced by the retreat of the LIS.

  16. Factors Controlling Slab Retreat and the Formation of Back-Arcs: Insights from Numerical Models

    NASA Astrophysics Data System (ADS)

    Huismans, R. S.; Grool, A.

    2014-12-01

    Although subduction is a first order plate tectonic process, the factors controlling the dynamics of slab roll-back and back-arc formation are still not very well understood. We present self-consistent thermo-mechanical models to study oceanic subduction, slab retreat, and back arc formation. We focus on two aspects of the subduction process: 1) factors that control retreat of the subduction zone, and 2) those that control the opening of the back arc. The model evolution is calculated using 2D plane strain thermo-mechanical finite element techniques for the finite element solution of incompressible viscous-plastic creeping flows (Fullsack, 1995). The models extend from the surface to 660 km depth. The upper surface of the model is free to move. We investigate interaction of the subducting slab with the overlying plate and focus on factors that may control the opening of a back-arc basin. The down going plate is driven by a kinematic boundary condition, far from the subduction zone. After an initial stage of far-field driven contraction, negative buoyant down welling of the oceanic lithosphere may drive continued subduction zone leading to mature subduction and the formation of an extensional back arc. The models suggest that two primary factors are required for slab retreat and the formation of an extensional back-arc system: 1) Convective destabilization and weakening of the overlying continental back arc region, and 2) sufficient negative buoyancy of the subducting plate.

  17. The effect of chloroform, orange oil and eucalyptol on root canal transportation in endodontic retreatment.

    PubMed

    Karataş, Ertuğrul; Kol, Elif; Bayrakdar, İbrahim Şevki; Arslan, Hakan

    2016-04-01

    The purpose of the present study was to assess the effect of solvents on root canal transportation in endodontic retreatment. Sixty extracted human permanent mandibular first molars with curved root canals were selected. All of the root canals were prepared using Twisted File Adaptive instruments (SybronEndo, Orange, CA, USA) and filled with gutta-percha and AH Plus sealer (Dentsply DeTrey, Konstanz, Germany) using the cold lateral compaction technique. The teeth were assigned to four retreatment groups as follows (n = 15): eucalyptol, chloroform, orange oil and control. The canals were scanned using cone-beam computed tomography scanning before and after instrumentation. The chloroform group showed a significantly higher mean transportation value than the orange oil and control groups at the 3 and 5 mm levels (P = 0.011 and P = 0.003, respectively). There was no significant difference among the orange oil, eucalyptol and control groups in terms of canal transportation (P > 0.61). The chloroform led to more canal transportation than the eucalyptol and orange oil during endodontic retreatment. PMID:26420757

  18. Diachronous retreat of the Greenland ice sheet during the last deglaciation

    NASA Astrophysics Data System (ADS)

    Sinclair, G.; Carlson, A. E.; Mix, A. C.; Lecavalier, B. S.; Milne, G.; Mathias, A.; Buizert, C.; DeConto, R.

    2016-08-01

    The last deglaciation is the most recent interval of large-scale climate change that drove the Greenland ice sheet from continental shelf to within its present extent. Here, we use a database of 645 published 10Be ages from Greenland to document the spatial and temporal patterns of retreat of the Greenland ice sheet during the last deglaciation. Following initial retreat of its marine margins, most land-based deglaciation occurred in Greenland following the end of the Younger Dryas cold period (12.9-11.7 ka). However, deglaciation in east Greenland peaked significantly earlier (13.0-11.5 ka) than that in south Greenland (11.0-10 ka) or west Greenland (10.5-7.0 ka). The terrestrial deglaciation of east and south Greenland coincide with adjacent ocean warming. 14C ages and a recent ice-sheet model reconstruction do not capture this progression of terrestrial deglacial ages from east to west Greenland, showing deglaciation occurring later than observed in 10Be ages. This model-data misfit likely reflects the absence of realistic ice-ocean interactions. We suggest that oceanic changes may have played an important role in driving the spatial-temporal ice-retreat pattern evident in the 10Be data.

  19. Accelerating frontal retreat and seasonal variability in North West Svalbard glaciers

    NASA Astrophysics Data System (ADS)

    Mansell, D.; Luckman, A.; Murray, T.

    2009-04-01

    Calving flux is a significant mass balance component for Svalbard glaciers. Calving processes in relation to fjord conditions, glacier velocity and frontal positions are currently poorly understood despite their importance. We present an unprecedented series of data showing ice-front behaviour and surface velocities for NW Svalbard glaciers and discuss the fundamental controls on the calving processes between 1991 and 2008. Glacier flow speeds, ice marginal position, and the presence and absence of fjord ice were derived from ERS, ENVISAT, ALOS and Landsat scenes, and melt modelling was used to investigate seasonal forcing. During this period many tidewater terminating glaciers in the region have shown accelerating rates of retreat, a few show steady retreat, and some remain stable. Superimposed on the long-term retreat of some glacier fronts, including Kronebreen, the fastest flowing glacier in Svalbard, is a seasonal signal which shows advance of the ice-front in the summer. By monitoring the terminus velocity and frontal position of outlet glaciers at high temporal resolution, both the magnitude and seasonality of the controlling processes are investigated and used to provide a better understanding of the impact of climate warming on Arctic ice loss.

  20. Health-Related Quality of Life in Patients With Locally Advanced Prostate Cancer After 76 Gy Intensity-Modulated Radiotherapy vs. 70 Gy Conformal Radiotherapy in a Prospective and Longitudinal Study

    SciTech Connect

    Lips, Irene Dehnad, Human; Kruger, Arto Boeken; Moorselaar, Jeroen van; Heide, Uulke van; Battermann, Jan; Vulpen, Marco van

    2007-11-01

    Purpose: To compare quality of life (QoL) after 70 Gy conformal radiotherapy with QoL after 76 Gy intensity-modulated radiotherapy (IMRT) in patients with locally advanced prostate carcinoma. Methods and Materials: Seventy-eight patients with locally advanced prostate cancer were treated with 70 Gy three-field conformal radiotherapy, and 92 patients received 76 Gy IMRT with fiducial markers for position verification. Quality of life was measured by RAND-36, the European Organization for Research and Treatment of Cancer core questionnaire (EORTC QLQ-C30(+3)), and the prostate-specific EORTC QLQ-PR25, before radiotherapy (baseline) and 1 month and 6 months after treatment. Quality of life changes in time (baseline vs. 1 month and baseline vs. 6 months) of {>=}10 points were considered clinically relevant. Results: Differences between the treatment groups for QoL changes over time occurred in several QoL domains. The 76-Gy group revealed no significant deterioration in QoL compared with the 70-Gy group. The IMRT 76-Gy group even demonstrated a significantly better change in QoL from baseline to 1 month in several domains. The conformal 70-Gy group revealed temporary deterioration in pain, role functioning, and urinary symptoms; for the IMRT 76-Gy group a better QoL in terms of change in health existed after 1 month, which persisted after 6 months. For both treatment groups temporary deterioration in physical role restriction occurred after 1 month, and an improvement in emotional role restriction occurred after 6 months. Sexual activity was reduced after treatment for both groups and remained decreased after 6 months. Conclusions: Intensity-modulated radiotherapy and accurate position verification seem to provide a possibility to increase the radiation dose for prostate cancer without deterioration in QoL.

  1. 14 CFR 27.1389 - Position light distribution and intensities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... minimum intensities in the horizontal plane, minimum intensities in any vertical plane, and maximum...: (1) Intensities in the horizontal plane. Each intensity in the horizontal plane (the plane containing the longitudinal axis of the rotorcraft and perpendicular to the plane of symmetry of the...

  2. 14 CFR 25.1389 - Position light distribution and intensities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... minimum intensities in the horizontal plane, minimum intensities in any vertical plane, and maximum...: (1) Intensities in the horizontal plane. Each intensity in the horizontal plane (the plane containing the longitudinal axis of the airplane and perpendicular to the plane of symmetry of the airplane)...

  3. Retreat of the Puget lobe of the Cordilleran Ice Sheet (Invited)

    NASA Astrophysics Data System (ADS)

    Haugerud, R. A.

    2010-12-01

    Systematic geomorphic mapping from high-resolution, digital lidar topography (e.g., http://pubs.usgs.gov/of/2009/1033/) is improving our understanding of the retreat of the Cordilleran ice sheet at the end of the last glaciation of northwest Washington. This history is of interest both because it provides a stratigraphic framework for earthquake-hazards studies and as an example of the interaction of grounded marine ice with rising sea level. The spatial distribution of outwash flats outlines a four-stage history of ice-margin retreat. Main stage is marked by drainage from the south margin of the Puget Lobe to the Chehalis valley via multiple channels. Russell stage began when ice retreated sufficiently for drainage to coalesce to a single path via Black Lake south of Olympia. Bretz stage began with a drop in local base level as ice-marginal drainage switched to a path across the Chimacum Peninsula southeast of Port Townsend. Whulge stage began when ice retreated from Admiralty Inlet, Glacial Lake Bretz drained, and Puget Sound became marine. A 5th, Sumas stage could be defined but ongoing work in the Bellingham area indicates that we don’t yet fully understand Sumas complexities. An apparently-folded outwash flat west of Bremerton provides what may be our best constraint on the frequency of large earthquakes on the Seattle fault (≥23 m differential uplift in ~16,000 years, or one 7-9 m uplift event per ~5,000 yrs); the weakest link in this argument is the assumption of southwards drainage from the retreating Puget Lobe. Several lines of evidence indicate that the Puget Lobe stagnated and melted in place: widespread dead-ice features; absence of end moraines between Olympia and central Whidbey Island; peculiarities in the outfall of Glacial Lake Bretz; and re-orientation of ice flow on northern Whidbey Island from N-S to NE-SW. Stagnation was likely caused by collapse of the Juan de Fuca lobe, which beheaded the Puget Lobe. Collapse was probably the result of a

  4. Asynchronous ice lobe retreat and glacial Lake Bascom: Deglaciation of the Hoosic and Vermont valleys, southwestern Vermont

    SciTech Connect

    Small, E.; Desimone, D. . Dept. of Geology)

    1993-03-01

    Deglaciation of the Hoosic River drainage basin in southwestern Vermont was more complex than previously described. Detailed surficial mapping, stratigraphic relationships, and terrace levels/delta elevations reveal new details in the chronology of glacial Lake Bascom: (1) a pre-Wisconsinan proglacial lake was present in a similar position to Lake Bascom as ice advanced: (2) the northern margin of 275m (900 ft) glacial Lake Bascom extended 10 km up the Vermont Valley; (3) the 215m (705 ft) Bascom level was stable and long lived; (4) intermediate water planes existed between 215m and 190m (625 ft) levels; and (5) a separate ice tongue existed in Shaftsbury Hollow damming a small glacial lake, here named glacial Lake Emmons. This information is used to correlate ice margins to different lake levels. Distance of ice margin retreat during a lake level can be measured. Lake levels are then used as control points on a Lake Bascom relative time line to compare rate of retreat of different ice tongues. Correlation of ice margins to Bascom levels indicates ice retreat was asynchronous between nearby tongues in southwestern Vermont. The Vermont Valley ice tongue retreated between two and four times faster than the Hoosic Valley tongue during the Bascom 275m level. Rate of retreat of the Vermont Valley tongue slowed to one-half of the Hoosic tongue during the 215m--190m lake levels. Factors responsible for varying rates of retreat are subglacial bedrock gradient, proximity to the Hudson-Champlain lobe, and the presence of absence of a calving margins. Asynchronous retreat produced splayed ice margins in southwestern Vermont. Findings from this study do not support the model of parallel, synchronous retreat proposed by many workers for this region.

  5. Pattern and timing of retreat of the last British-Irish Ice Sheet

    NASA Astrophysics Data System (ADS)

    Clark, Chris D.; Hughes, Anna L. C.; Greenwood, Sarah L.; Jordan, Colm; Sejrup, Hans Petter

    2012-06-01

    During the last glacial the ice sheet that subsumed most of Britain, Ireland and the North Sea attained its maximum extent by 27 ka BP and with an ice volume sufficient to raise global sea level by ca 2.5 m when it melted. We reconstruct the demise of this British-Irish Ice Sheet (BIIS) and present palaeo-glaciological maps of retreat stages between 27 and 15 ka BP. The whole land area was investigated using remote sensing data and we present maps of moraines, meltwater channels, eskers, and drumlins and a methodology of how to interpret and bring them together. For the continental shelf, numerous large moraines were discovered recording an extensive pattern of retreat stretching from SW Ireland to the Shetland Isles. From an integration of this new mapping of glacial geomorphology (>26,000 landforms) with previously published evidence, compiled in the BRITICE database, we derive a pattern of retreat for the whole BIIS. We review and compile relevant dates (881 examples) that constrain the timing of retreat. All data are held within a Geographic Information System (GIS), and are deciphered to produce a best-estimate of the combined pattern and timing of retreat. Pattern information reveals an ice sheet mainly comprised of a shelf-parallel configuration from SW Ireland to NE Scotland but it spread far enough to the south to incorporate outlying ice domes over Wales, the Lake District and Kerry. Final disintegration was into a number of separate ice caps, rather than reduction as a single mass, and paradoxically, retreat was not always back to high ground. By 23 ka BP ice withdrew along its northern boundaries at the same time as the southern margins were expanding, including transient ice streaming down the Irish Sea and advances of lobes in the Cheshire Basin, Vale of York and east coast of England. Ice divides migrated south. By 19 ka the ice sheet was in crisis with widespread marine-based ice losses, particularly in the northern North Sea and the Irish Sea

  6. Eocene sea retreat out of Asia: paleogeography, controlling mechanisms and environmental impacts

    NASA Astrophysics Data System (ADS)

    Dupont-Nivet, Guillaume; Bosboom, Roderic; Proust, Jean-Noël; Mandic, Oleg; Villa, Giuliana; Grothe, Arjan; Stoica, Marius; Guo, Zhaojie; Krijgsman, Wout; Yang, Wei; Bougeois, Laurie; Aminov, Jovid; Ormukov, Cholponbec; Huang, Wentao

    2014-05-01

    The sediments of the Central Asian basins include the remnants of the easternmost extent of a large epicontinental sea. Before it retreated westward and eventually separated as the Paratethys Sea following the Eocene-Oligocene transition (EOT), this shallow marine sea extended across the Eurasian continent from the Mediterranean Tethys in the west to the Tarim Basin in western China in the east. However, the paleogeography and the timing of the westward retreat of the proto-Paratethys Sea are too poorly constrained to identify its proposed controlling mechanisms and paleoenvironmental impacts. The sea supposedly entered Central Asia in the Cretaceous and five third-order marine incursions have been recognized from the Cretaceous-Paleogene sedimentary record, of which the last two transgressions are documented here. We studied the sea retreat in the Tarim Basin in western China, the Alai Valley and Ferghana Basin in southern Kyrgyzstan and the Afghan-Tajik Basin in south-western Tajikistan. Integrated bio-magnetostratigraphic dating shows that the sea retreated westward from the Tarim Basin in stepwise fashion. The major fourth transgression occurred during the Lutetian, after which the sea retreated from the southwest Tarim Basin paleodepocenter at ~41 Ma (base C18r). The last and fifth transgression was restricted to the westernmost margin of the Tarim basin and occurred during latest Bartonian-early Priabonian (base C17n.3n-base C16n.1n). At the level of precision of our dating, each of these marine incursions is apparently synchronous across the Tarim Basin suggesting rapid regional transgression/regression cycles in these shallow epicontinental basins with limited diachroneity. The shallow marine near-shore sediments of these last two transgressions can be convincingly correlated by litho- and biostratigraphy across Central Asia, showing for the first time that the sea may have largely retreated from Central Asia in the late Eocene. The lack of apparent

  7. Cost-effectiveness of retreatment with varenicline after failure with or relapse after initial treatment for smoking cessation

    PubMed Central

    Annemans, Lieven; Marbaix, Sophie; Nackaerts, Kristiaan; Bartsch, Pierre

    2015-01-01

    Objectives A recent trial showed the clinical benefit of retreatment with varenicline in subjects failing on the initial treatment, or relapsing after initial success. The objective of this study was to evaluate the cost-effectiveness of retreatment with varenicline compared with other smoking cessation interventions. Methods A published Markov model was adapted to compare one quit attempt of varenicline followed by retreatment to treatment/retreatment with nicotine replacement therapy (NRT), bupropion or placebo, and with only 1 quit attempt of varenicline. Efficacy was obtained from clinical trials. Incidence of smoking-related diseases was based on published data. Cost of therapies and complications was obtained from databases and literature. Results For 1000 smokers willing to quit, varenicline retreatment saves 275,000€, 118,000€, 316,000€ and 237,000€ compared to NRT, bupropion, placebo, or one single varenicline quit attempt respectively at lifetime and from the healthcare payer perspective. The number of quality adjusted life years gained is 74, 63, 193 and 111 respectively. Sensitivity analyses showed the robustness of these findings. Conclusion This analysis suggests that in the long term, varenicline retreatment is a dominant intervention, meaning both greater health gains and greater costs saved, over other possible interventions and therefore should be considered as a standard option. PMID:26844072

  8. Scholarly Retreat

    ERIC Educational Resources Information Center

    Boyle, Robert R.; Pellegrini, Barbara J.; McGrew, Jean B.

    2003-01-01

    Advanced placement teachers around Chicago find their own intellectual stimulation reinvigorates their teaching and benefits their students. Through a consortium, these teachers group together to explore content-based topics using a rich variety of community resources, including a top library, university and museum resources. "This is my…

  9. Longitudinal Bunch Dynamics in the Tevatron

    SciTech Connect

    R. Moore et al.

    2003-06-02

    The authors present their observations of the longitudinal bunch dynamics in Tevatron for uncoalesced proton bunches at 150 GeV and coalesced proton bunches at 150 GeV and 980 GeV. They have observed long-term (> 15 minutes) coherent oscillations of uncoalesced protons that preserve already existing oscillations from upstream accelerators. A single-bunch instability in large intensity protons bunches at 980 GeV has also been observed.

  10. Relaxed Intensity

    ERIC Educational Resources Information Center

    Ramey, Kyle

    2004-01-01

    Relaxed intensity refers to a professional philosophy, demeanor, and way of life. It is the key to being an effective educational leader. To be successful one must be relaxed, which means managing stress efficiently, having fun, and enjoying work. Intensity allows one to get the job done and accomplish certain tasks or goals. Educational leaders…