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Sample records for isolated rib optial

  1. Cutoff-mesa isolated rib optical waveguide for III-V heterostructure photonic integrated circuits

    DOEpatents

    Vawter, Gregory A.; Smith, Robert E.

    1998-01-01

    A cutoff mesa rib waveguide provides single-mode performance regardless of any deep etches that might be used for electrical isolation between integrated electrooptic devices. Utilizing a principle of a cutoff slab waveguide with an asymmetrical refractive index profile, single mode operation is achievable with a wide range of rib widths and does not require demanding etch depth tolerances. This new waveguide design eliminates reflection effects, or self-interference, commonly seen when conventional rib waveguides are combined with deep isolation etches and thereby reduces high order mode propagation and crosstalk compared to the conventional rib waveguides.

  2. Cutoff-mesa isolated rib optical waveguide for III-V heterostructure photonic integrated circuits

    DOEpatents

    Vawter, G.A.; Smith, R.E.

    1998-04-28

    A cutoff mesa rib waveguide provides single-mode performance regardless of any deep etches that might be used for electrical isolation between integrated electrooptic devices. Utilizing a principle of a cutoff slab waveguide with an asymmetrical refractive index profile, single mode operation is achievable with a wide range of rib widths and does not require demanding etch depth tolerances. This new waveguide design eliminates reflection effects, or self-interference, commonly seen when conventional rib waveguides are combined with deep isolation etches and thereby reduces high order mode propagation and crosstalk compared to the conventional rib waveguides. 7 figs.

  3. Action of the isolated canine diaphragm on the lower ribs at high lung volumes

    PubMed Central

    De Troyer, André; Wilson, Theodore A

    2014-01-01

    The normal diaphragm has an inspiratory action on the lower ribs, but subjects with chronic obstructive pulmonary disease commonly have an inward displacement of the lateral portions of the lower rib cage during inspiration. This paradoxical displacement, conventionally called ‘Hoover's sign’, has traditionally been attributed to the direct action of radially oriented diaphragmatic muscle fibres. In the present study, the inspiratory intercostal muscles in all interspaces in anaesthetized dogs were severed so that the diaphragm was the only muscle active during inspiration. The displacements of the lower ribs along the craniocaudal and laterolateral axes and the changes in pleural pressure (ΔPpl) and transdiaphragmatic pressure were measured during occluded breaths and mechanical ventilation at different lung volumes between functional residual capacity (FRC) and total lung capacity. From these data, the separate effects on rib displacement of ΔPpl and of the force exerted by the diaphragm on the ribs were determined. Isolated spontaneous diaphragm contraction at FRC displaced the lower ribs cranially and outward, but this motion was progressively reversed into a caudal and inward motion as lung volume increased. However, although the force exerted by the diaphragm on the ribs decreased with increasing volume, it continued to displace the ribs cranially and outward. These observations suggest that Hoover's sign is usually caused by the decrease in the zone of apposition and, thus, by the dominant effect of ΔPpl on the lower ribs, rather than an inward pull from the diaphragm. PMID:25063819

  4. Design Features Of K = 100 Cyclotron Magnet For ISOL RIB Production

    SciTech Connect

    Park, Jin Ah; Gad, Kh. M. M.; Chai, Jong-Seo

    2011-06-01

    K = 100 Separated Sector Cyclotron was designed in conceptual for the ISOL driver. It has 4 separated sector magnets. Two SF cyclotrons will be used as the injectors for separated sector cyclotron. RF frequency is 70 MHz, 4th harmonics. We have designed sector magnet without trim and harmonic coils. Minimum radius of the magnet is 55 cm and maximum radius is 1.8 m. Designed magnets were calculated and simulated by OPERA 3D (TOSCA) code. Ion beam dynamics calculations have been done using particle studio code to prove the focusing properties of the designed magnets.

  5. Rib fracture - aftercare

    MedlinePlus

    A rib fracture is a crack or break in one or more of your rib bones. Your ribs are the round, flat bones in your chest ... A rib fracture can be very painful because your ribs move when you breathe, cough, and move your upper ...

  6. Ribbed Swimsuit

    NASA Technical Reports Server (NTRS)

    1996-01-01

    Langley Research Center's turbulent-drag reduction technology, as applied to airplanes and the winning yacht in America's Cup, finds another application: swimwear. The Strush SR swimsuit features silicon ribbing or "riblets" at the chest and buttocks, reducing friction in the water. Combined with innovations by its manufacturer, Arena North America, the company says the technology makes the suit 10 to 15 percent faster than any other world class swimsuit. The publicity for the Strush SR is handled by Suter Communications, Inc. *Company no longer exists (12/5/96).

  7. [Spinal cord compression disclosing rib hydatidosis].

    PubMed

    Ousehal, A; Adil, A; El Azhari, A; Kadiri, R

    1995-12-01

    The authors report an exceptional case of spinal compression following an isolate rib hydatidosis. The CT scan has suspected the diagnosis. The authors recall the anatomoclinic features and specify the radiologic aspects of the osseous hydatidosis, especially the rib's localization which is very rare. MR imaging in addition of its diagnosis role showing a very evocative cyst images, is the exam of choice in order to appreciate the disease's extent and the degree of medular sufferance. PMID:8676297

  8. Ribbed electrode substrates

    DOEpatents

    Breault, Richard D.; Goller, Glen J.

    1983-01-01

    A ribbed substrate for an electrochemical cell electrode is made from a mixture of carbon fibers and carbonizable resin and has a mean pore size in the ribs which is 60-75% of the mean pore size of the web portions of the substrate which interconnect the ribs. Preferably the mean pore size of the web portion is 25-45 microns; and, if the substrate includes edge seals parallel to the ribs, the edge seals preferably have a mean pore size no greater than about ten microns. Most preferably the substrate has the same ratio of carbon fibers to polymeric carbon in all areas, including the ribs, webs, and edge seals. A substrate according to the present invention will have better overall performance than prior art substrates and minimizes the substrate thickness required for the substrate to perform all its functions well.

  9. Nineth Rib Syndrome after 10th Rib Resection

    PubMed Central

    Yu, Hyun Jeong; Jeong, Yu Sub; Lee, Dong Hoon

    2016-01-01

    The 12th rib syndrome is a disease that causes pain between the upper abdomen and the lower chest. It is assumed that the impinging on the nerves between the ribs causes pain in the lower chest, upper abdomen, and flank. A 74-year-old female patient visited a pain clinic complaining of pain in her back, and left chest wall at a 7 on the 0-10 Numeric Rating scale (NRS). She had a lateral fixation at T12-L2, 6 years earlier. After the operation, she had multiple osteoporotic compression fractures. When the spine was bent, the patient complained about a sharp pain in the left mid-axillary line and radiating pain toward the abdomen. On physical examination, the 10th rib was not felt, and an image of the rib-cage confirmed that the left 10th rib was severed. When applying pressure from the legs to the 9th rib of the patient, pain was reproduced. Therefore, the patient was diagnosed with 9th rib syndrome, and ultrasound-guided 9th and 10th intercostal nerve blocks were performed around the tips of the severed 10th rib. In addition, local anesthetics with triamcinolone were administered into the muscles beneath the 9th rib at the point of the greatest tenderness. The patient's pain was reduced to NRS 2 point. In this case, it is suspected that the patient had a partial resection of the left 10th rib in the past, and subsequent compression fractures at T8 and T9 led to the deformation of the rib cage, causing the tip of the remaining 10th rib to impinge on the 9th intercostal nerves, causing pain. PMID:27413484

  10. Use of rib belts in acute rib fractures.

    PubMed

    Lazcano, A; Dougherty, J M; Kruger, M

    1989-01-01

    The current treatment for uncomplicated rib fractures is the exclusion of associated injuries followed by symptomatic treatment with analgesics. Encouragement of deep breathing is also recommended to avoid secondary or delayed pulmonary complications. The use of circumferential rib belts in treating patients with acute rib fractures has been discouraged because of possible complications from restricted ventilation. A review of the literature revealed no previous clinical studies to support this view. We designed and conducted a controlled, prospective, randomized pilot study to determine if there was any increased morbidity associated with the use of rib belts in the treatment of patients with acute rib fractures. Twenty-five adult patients with radiographically proven acute rib fractures were randomized into two groups. The first group was treated with analgesics and a standard circumferential rib belt (Zimmer Universal Rib Belt). The second group was treated with oral analgesics alone. Patients were contacted by telephone three days after the initial injury and then reexamined 14 days postinjury. Rates of pain resolution, compliance, and delayed complications were determined. Rib belts were not found to significantly reduce the severity of pain. Four complications (one case of bloody pleural effusion requiring hospitalization, two cases of asymptomatic discoid atelectasis, and one case of allergic contact dermatitis) were identified, all occurring in the group of patients receiving rib belts. This pilot study indicates that while rib belts are widely accepted by patients for control of pain, they appear to be associated with an increased incidence of complications. Clinical studies with larger sample sizes will be needed to confirm these findings. PMID:2643965

  11. Nonunion of a first rib fracture in a gymnast.

    PubMed

    Proffer, D S; Patton, J J; Jackson, D W

    1991-01-01

    Isolated fracture of the first rib is uncommon, but has been reported to occur in sports such as basketball, baseball, and dancing. It has not been reported to occur in gymnasts. Usually, these fractures heal with an adequate period of rest. Rarely do first rib fractures become nonunions. They have been felt to be asymptomatic and are usually found incidentally on routine chest roentgenograms. Symptomatic nonunion of a first rib fracture has not been reported previously. Our patient did not respond to nonoperative treatment and required surgical intervention to alleviate her symptoms. We agree that most fractures of this type heal without complications. However, if a persistently symptomatic nonunion ensues, we suggest transaxillary resection of 90% or more of the first rib. PMID:2039074

  12. Delivering multiple independent RIB simultaneously: Technical and operational challenges

    NASA Astrophysics Data System (ADS)

    Morton, A. C.

    2016-06-01

    ISAC is an ISOL-type facility at which RIB are produced by direct reactions of 480 MeV protons from TRIUMFs main cyclotron on thick targets. Like other ISOL-type facilities, ISAC is limited to the production and delivery of a single RIB at any given time. ARIEL, the Advanced Rare-IsotopE Laboratory, will provide for the production and delivery of, ultimately, two additional RIB, the first produced by photofission on actinide targets using electrons from a new superconducting electron linac and the second by direct and indirect reactions with protons from TRIUMFs main cyclotron. This will allow for the simultaneous delivery of three independent RIB to experimental areas at ARIEL and ISAC. The shift from single-user to multi-user operation will introduce significant technical and operational challenges that RIB facilities have not yet had to address. Almost all aspects of facility operation will become more complex as the first RIB from ARIEL targets become available.

  13. Morphometric analysis of variation in the ribs with age and sex.

    PubMed

    Weaver, Ashley A; Schoell, Samantha L; Stitzel, Joel D

    2014-08-01

    Rib cage morphology changes with age and sex are expected to affect thoracic injury mechanisms and tolerance, particularly for vulnerable populations such as pediatrics and the elderly. The size and shape variation of the external geometry of the ribs was characterized for males and females aged 0-100 years. Computed tomography (CT) scans from 339 subjects were analyzed to collect between 2700 and 10 400 homologous landmarks from each rib. Rib landmarks were analyzed using the geometric morphometric technique known as Procrustes superimposition. Age- and sex-specific functions of 3D rib morphology were produced representing the combined size and shape variation and the isolated shape variation. Statistically significant changes in the size and shape variation (P < 0.0001) and shape variation (P < 0.0053) of all 24 ribs were found to occur with age in males and females. Rib geometry, location, and orientation varied according to the rib level. From birth through adolescence, the rib cage experienced an increase in size, a decrease in thoracic kyphosis, and inferior rotation of the ribs relative to the spine within the sagittal plane. From young adulthood into elderly age, the rib cage experienced increased thoracic kyphosis and superior rotation of the ribs relative to the spine within the sagittal plane. The increased roundedness of the rib cage and horizontal angling of the ribs relative to the spine with age influences the biomechanical response of the thorax. With the plane of the rib oriented more horizontally, loading applied in the anterior-posterior direction will result in increased deformation within the plane of the rib and an increased risk for rib fractures. Thus, morphological changes may be a contributing factor to the increased incidence of rib fractures in the elderly. The morphological functions derived in this study capture substantially more information on thoracic skeleton morphology variation with age and sex than is currently available

  14. Morphometric analysis of variation in the ribs with age and sex

    PubMed Central

    Weaver, Ashley A; Schoell, Samantha L; Stitzel, Joel D

    2014-01-01

    Rib cage morphology changes with age and sex are expected to affect thoracic injury mechanisms and tolerance, particularly for vulnerable populations such as pediatrics and the elderly. The size and shape variation of the external geometry of the ribs was characterized for males and females aged 0–100 years. Computed tomography (CT) scans from 339 subjects were analyzed to collect between 2700 and 10 400 homologous landmarks from each rib. Rib landmarks were analyzed using the geometric morphometric technique known as Procrustes superimposition. Age- and sex-specific functions of 3D rib morphology were produced representing the combined size and shape variation and the isolated shape variation. Statistically significant changes in the size and shape variation (P < 0.0001) and shape variation (P < 0.0053) of all 24 ribs were found to occur with age in males and females. Rib geometry, location, and orientation varied according to the rib level. From birth through adolescence, the rib cage experienced an increase in size, a decrease in thoracic kyphosis, and inferior rotation of the ribs relative to the spine within the sagittal plane. From young adulthood into elderly age, the rib cage experienced increased thoracic kyphosis and superior rotation of the ribs relative to the spine within the sagittal plane. The increased roundedness of the rib cage and horizontal angling of the ribs relative to the spine with age influences the biomechanical response of the thorax. With the plane of the rib oriented more horizontally, loading applied in the anterior-posterior direction will result in increased deformation within the plane of the rib and an increased risk for rib fractures. Thus, morphological changes may be a contributing factor to the increased incidence of rib fractures in the elderly. The morphological functions derived in this study capture substantially more information on thoracic skeleton morphology variation with age and sex than is currently available in

  15. Heat transfer and friction factors in the ribbed square convergent and divergent channels

    NASA Astrophysics Data System (ADS)

    Lee, M. S.; Ahn, S. W.

    2016-06-01

    Heat transfer and friction factors are reported for the measurements of turbulent flows in the convergent and divergent square channels with one-sided ribbed wall as well as two opposite in-line ribbed walls. The study covers three different hydraulic diameter ratios between inlet and exit at the test section such as Dho/Dhi = 0.75, 1.0, and 1.33 and Reynolds numbers in the range of 25,000-79,000. The channels, composing of ten isolated copper sections in the length of test section of 1 m, have the hydraulic diameter of 87.5 mm for the straight channel (Dho/Dhi = 1.0); the rib height-to-hydraulic diameter is 0.114; the rib pitch-to-height ratio equals 10. On the contrary to public opinion that the friction factor depends on the portion of the ribbed area, the total friction factor in the two opposite ribbed walls are lower than in the one-sided ribbed wall in the divergent channel of Dho/Dhi = 1.33 because the total pressure, summing positive dynamic and negative static pressures, is acted. The results show that the two opposite ribbed divergent channel of Dho/Dhi = 1.33 provides the best heat transfer enhancement and the two opposite ribbed convergent channel of Dho/Dhi = 0.75 provides the worst friction factor enhancement, and the ribbed divergent channels are generally recommended.

  16. Radial rib antenna surface deviation analysis program

    NASA Technical Reports Server (NTRS)

    Coyner, J. V., Jr.

    1971-01-01

    A digital computer program was developed which analyzes any radial rib antenna with ribs radiating from a central hub. The program has the capability for calculating the antenna surface contour (reversed pillowing effect), the optimum rib shape for minimizing the rms surface error, and the actual rms surface error. Rib deflection due to mesh tension and catenary cable tension can also be compensated for, and the pattern from which the mesh gores are cut can be determined.

  17. The Design of Airplane Wing Ribs

    NASA Technical Reports Server (NTRS)

    Newlin, J A; Trayer, George W

    1931-01-01

    The purpose of this investigation was to obtain information for use in the design of truss and plywood forms, particularly with reference to wing ribs. Tests were made on many designs of wing ribs, comparing different types in various sizes. Many tests were also made on parallel-chord specimens of truss and plywood forms in place of the actual ribs and on parts of wing ribs, such as truss diagonals and sections of cap strips. It was found that for ribs of any size or proportions, when they were designed to obtain a well-balanced construction and were carefully manufactured, distinct types are of various efficiencies; the efficiency is based on the strength per unit of weight. In all types of ribs the heavier are the stronger per unit of weight. Reductions in the weight of wing ribs are accompanied even in efficient designs by a much greater proportional reduction in strength.

  18. Rib forming tool for tubing

    DOEpatents

    Rowley, James P.; Lewandowski, Edward F.; Groh, Edward F.

    1976-01-01

    Three cylindrical rollers are rotatably mounted equidistant from the center of a hollow tool head on radii spaced 120.degree. apart. Each roller has a thin flange; the three flanges lie in a single plane to form an internal circumferential rib in a rotating tubular workpiece. The tool head has two complementary parts with two rollers in one part of the head and one roller in the other part; the two parts are joined by a hinge. A second hinge, located so the rollers are between the two hinges, connects one of the parts to a tool bar mounted in a lathe tool holder. The axes of rotation of both hinges and all three rollers are parallel. A hole exposing equal portions of the three roller flanges is located in the center of the tool head. The two hinges permit the tool head to be opened and rotated slightly downward, taking the roller flanges out of the path of the workpiece which is supported on both ends and rotated by the lathe. The parts of the tool head are then closed on the workpiece so that the flanges are applied to the workpiece and form the rib. The tool is then relocated for forming of the next rib.

  19. A rib abnormality mimicking pulmonary nodule: a pitfall in the plain chest x-ray.

    PubMed

    Akturk, Yeliz; Günes, Serra Ozbal; Hekimoglu, Baki

    2016-01-01

    The ribs show a wide range of normal and pathologic radiographic appearences as well as congenital variations. Intrathoracic ribs are isolated and rare anomalies. They are usually super-numerary, more often right-sided, and involve the middle part of the thorax. We describe a case with intrathorasic rib abnormality mimicking a peripheral metastatic lung nodule in the plain chest x-ray and emphasize the use of coronal and sagittal reformatted images in thorasic imaging. Utilisation of multiplanar reformatted images in chest computerised tomography increase diagnostic quality. PMID:27374213

  20. Segmentation of ribs in digital chest radiographs

    NASA Astrophysics Data System (ADS)

    Cong, Lin; Guo, Wei; Li, Qiang

    2016-03-01

    Ribs and clavicles in posterior-anterior (PA) digital chest radiographs often overlap with lung abnormalities such as nodules, and cause missing of these abnormalities, it is therefore necessary to remove or reduce the ribs in chest radiographs. The purpose of this study was to develop a fully automated algorithm to segment ribs within lung area in digital radiography (DR) for removal of the ribs. The rib segmentation algorithm consists of three steps. Firstly, a radiograph was pre-processed for contrast adjustment and noise removal; second, generalized Hough transform was employed to localize the lower boundary of the ribs. In the third step, a novel bilateral dynamic programming algorithm was used to accurately segment the upper and lower boundaries of ribs simultaneously. The width of the ribs and the smoothness of the rib boundaries were incorporated in the cost function of the bilateral dynamic programming for obtaining consistent results for the upper and lower boundaries. Our database consisted of 93 DR images, including, respectively, 23 and 70 images acquired with a DR system from Shanghai United-Imaging Healthcare Co. and from GE Healthcare Co. The rib localization algorithm achieved a sensitivity of 98.2% with 0.1 false positives per image. The accuracy of the detected ribs was further evaluated subjectively in 3 levels: "1", good; "2", acceptable; "3", poor. The percentages of good, acceptable, and poor segmentation results were 91.1%, 7.2%, and 1.7%, respectively. Our algorithm can obtain good segmentation results for ribs in chest radiography and would be useful for rib reduction in our future study.

  1. The tagged RIBs facility of LNS

    SciTech Connect

    De Napoli, M.; Raciti, G.; Rapisarda, E.; Cardella, G.; Amorini, F.; Calabretta, L.; Sfienti, C.

    2007-11-30

    Radioactive Ion Beams (RIBs) are produced In-Flight at the Laboratori Nazionali del Sud (LNS) by projectile fragmentation on light targets at intermediate energies. RIBs rates up to 10{sup 5} ions/sec have been measured and about 95% of secondary beam has been transported up to one of the experimental caves. The {delta}E-ToF identification method was successfully applied to tag, event-by-event, the RIBs before the interaction with a secondary reaction target.

  2. The slipping rib syndrome: A case report

    PubMed Central

    van Delft, E.A.K.; van Pul, K.M.; Bloemers, F.W.

    2016-01-01

    We present a case report and review of literature about slipping rib syndrome, a syndrome rarely recognized and often un or misdiagnosed. In literature there is no clear consensus about the diagnosis and treatment. We present a case of a 47 year old man who was diagnosed with slipping rib syndrome after a cycling incident 8 years ago. Also, we developed a flow chart according the diagnostic and therapeutic steps in the treatment of slipping rib syndrome. Central massage Knowledge and treatment of the slipping rib syndrome can prevent chronic complaints and unnecessary comprehensive treatment. PMID:27082995

  3. Turbine bucket natural frequency tuning rib

    DOEpatents

    Wang, John Zhiqiang; Norton, Paul Francis; Barb, Kevin Joseph; Jacala, Ariel Caesar-Prepena

    2002-01-01

    A tuning rib is added preferably in the aft cavity of a cored turbine bucket to alter the bucket's natural frequencies. The tuning rib may be a solid rib or a segmented rib and is particularly suited for altering high order frequency modes such as 2T, 4F and 1-3S. As such, detrimental crossings of natural bucket frequencies and gas turbine stimuli can be avoided to thereby improve the reliability of a gas turbine without impacting other features of the bucket that are important to the performance of the gas turbine.

  4. Material properties of human rib cortical bone from dynamic tension coupon testing.

    PubMed

    Kemper, Andrew R; McNally, Craig; Kennedy, Eric A; Manoogian, Sarah J; Rath, Amber L; Ng, Tracy P; Stitzel, Joel D; Smith, Eric P; Duma, Stefan M; Matsuoka, Fumio

    2005-11-01

    The purpose of this study was to develop material properties of human rib cortical bone using dynamic tension coupon testing. This study presents 117 human rib cortical bone coupon tests from six cadavers, three male and three female, ranging in age from 18 to 67 years old. The rib sections were taken from the anterior, lateral, and posterior regions on ribs 1 through 12 of each cadaver's rib cage. The cortical bone was isolated from each rib section with a low speed diamond saw, and milled into dog bone shaped tension coupons using a small computer numerical control machine. A high-rate servo-hydraulic Material Testing System equipped with a custom slack adaptor, to provide constant strain rates, was used to apply tension loads to failure at an average rate of 0.5 strains/sec. The elastic modulus, yield stress, yield strain, ultimate stress, ultimate strain, and strain energy density were determined from the resulting stress versus strain curves. The overall average of all cadaver data gives an elastic modulus of 13.9 GPa, a yield stress of 93.9 MPa, a yield strain of 0.88 %, an ultimate stress of 124.2 MPa, an ultimate strain of 2.7 %, and a strain energy density of 250.1 MPa-microstrain. For all cadavers, the plastic region of the stress versus strain curves was substantial and contributed approximately 60 % to the strain energy and over 80 % in the tests with the 18 year old cadaver. The rib cortical bone becomes more brittle with increasing age, shown by an increase in the modulus (p < 0.01) and a decrease in peak strain (p < 0.01). In contrast to previous three-bending tests on whole rib and rib cortical bone coupons, there were no significant differences in material properties with respect to rib region or rib level. When these results are considered in conjunction with the previous three-point bending tests, there is regional variation in the structural response of the human rib cage, but this variation appears to be primarily a result of changes in the

  5. Turbulent structures and budgets behind permeable ribs

    SciTech Connect

    Panigrahi, P.K.; Schroeder, A.; Kompenhans, J.

    2008-02-15

    Different rib geometries are traditionally used to improve heat transfer and enhance mixing in different industrial applications, i.e. heat exchangers, cooling passages of gas turbine blades and fuel elements of nuclear reactors, etc. Permeable ribs have been proposed in literature for passive control of the reattaching flow past surface mounted ribs leading to superior performance. The flow past different surface mounted permeable rib geometries, i.e. solid, slit, split-slit and inclined split-slit ribs have been investigated in this study. Both two components and stereo particle image velocimetry (PIV) have been used in streamwise and cross stream planes to study the underlying flow structures. The detailed turbulent statistics, i.e. mean and rms velocity, higher order moments, quadrant decomposition of turbulent shear stress producing motions, skewness and components of the turbulent kinetic energy budgets have been compared for different rib geometries. Coherent structures are identified based on the invariant of velocity gradient tensor invariant and wavelet transform. The skewness results demonstrate the intermittency of quadrant motions. The reattachment length of the inclined split-slit rib is lowest among all rib geometries. The average Reynolds stresses and the production of turbulent kinetic energy are highest for the inclined split-slit rib. The pressure transport calculated as residual of the turbulent kinetic energy budget equation is highest for the inclined split-slit rib. This is attributed to the smaller reattachment length leading to greater adverse pressure gradient for the inclined split-slit rib. The quadrant motions, turbulent fluxes, skewness and kinetic energy budgets at post reattachment region compares well with that of flat plate turbulent boundary layer from hot wire measurements in literature. Overall, this study demonstrates the effectiveness of PIV technique for the detailed turbulent structures characterization of complex flows

  6. Fabricational morphology of oblique ribs in bivalves.

    PubMed

    Checa, Antonio G

    2002-11-01

    The formation of oblique ribs of bivalve shells usually has been attributed to processes of reaction-diffusion of morphogens from cell to cell at the mantle margin or neural activation and lateral inhibition in the mantle. In particular, such ribs appear with high rates of lateral diffusion. Nevertheless, theoretical models fail to explain either partially or wholly some varieties of oblique ribs. After surveying the modes of formation of the shell and oblique ribs by the bivalve mantle and associated fabricational defects, I have determined that the mantle is able to develop an elaborate behavior in order to displace the rib in a particular direction during growth. The mantle margin is, therefore, not only the shell-secreting organ, but also the main morphogenetic unit. In particular, there are two main fabricational strategies. In forms with strict contact guidance (SCG) the mantle is able to project far enough beyond the shell margins so as to feel the already formed reliefs and to align new growth increments of the ribs in the appropriate directions. The shell margin is always strongly reflected. In bivalves with reduced contact guidance plus constant lateral shift (RCG), the margin is usually acute and the information about ribs available to the mantle is reduced. During rib construction the mantle extrudes slightly from the shell edge and then pushes laterally by muscular action; in this way, the new growth increment of the rib is displaced laterally on a small scale. The contact-guidance model is supported also by the homogeneous structure of the shell-secreting mantle. From the morphogenetic standpoint, oblique ribs are related to commarginal ones and both differ completely from other ribbing patterns of bivalves. PMID:12353301

  7. BILATERAL FIRST RIB FRACTURE IN A DIVE WITH LIFE VEST

    PubMed Central

    Sandri, Pietro de Almeida; de Almeida, Joelmar César; Sandri, João Luiz

    2015-01-01

    First-rib fractures are uncommon and are generally related to major thoracic trauma: so much so that they serve to indicate the severity of the trauma. Isolated bilateral first-rib fractures without major thoracic trauma are rarely described in the literature. The symptoms may go unnoticed and be minimized, thus making this condition difficult to diagnose. The present report presents a case of direct trauma on the supraclavicular region with symptoms of contusion of the brachial plexus, caused by a fall from a jet ski while a life vest was being used. The literature was reviewed to show the various facets of the problem and the treatment for this condition was discussed. PMID:27022557

  8. Molecular-Flow Properties of RIB Type Vapor-Transport Systems Using a Fast-Valve

    SciTech Connect

    Alton, Gerald D; Bilheux, Hassina Z; Zhang, Y.; Liu, Yuan

    2014-01-01

    The advent of the fast-valve device, described previously, permits measurement of molecular-flow times of chemically active or inactive gaseous species through radioactive ion beam (RIB) target ion source systems, independent of size, geometry and materials of construction. Thus, decay losses of short-half-life RIBs can be determined for a given target/vapor-transport system in advance of on-line operation, thereby ascertaining the feasibility of the system design for successful processing of a given isotope. In this article, molecular-flow-time theory and experimentally measured molecular-flow time data are given for serial- and parallel-coupled Ta metal RIB vapor-transport systems similar to those used at ISOL based RIB facilities. In addition, the effect of source type on the molecular-flow time properties of a given system is addressed, and a chemical passivation method for negating surface adsorption enthalpies for chemically active gaseous species on Ta surfaces is demonstrated.

  9. Jet flow on ribbed curved surfaces

    NASA Astrophysics Data System (ADS)

    Lashkov, Iu. A.; Sokolova, I. N.; Shumilkina, E. A.

    1992-02-01

    The objective of the study was to investigate the possibility of using microribbing to reduce turbulent friction in Coanda flows over curved surfaces. It is shown that ribs make it possible to reduce the effect of a jet impinging on an obstacle and to prevent the Coanda effect when jet attachment is undesirable. The optimal rib parameters are determined.

  10. Acute hematogenous osteomyelitis of the rib

    SciTech Connect

    Levinsohn, E.M.; Sternick, A.; Echeverria, T.S.; Yuan, H.A.

    1982-08-01

    Two cases of acute hematogenous osteomyelitis of the rib are presented. In one case the etiologic agent was Staphylococcus aureus coagulase-positive and in the other it was Bacteroides corrodens. Although an uncommon disease, hematogenous osteomyelitis should be considered in the differential diagnosis of destructive lesions of the rib. Anaerobic and aerobic cultures should be obtained for bacteriologic analysis.

  11. Nozzle airfoil having movable nozzle ribs

    DOEpatents

    Yu, Yufeng Phillip; Itzel, Gary Michael

    2002-01-01

    A nozzle vane or airfoil structure is provided in which the nozzle ribs are connected to the side walls of the vane or airfoil in such a way that the ribs provide the requisite mechanical support between the concave side and convex side of the airfoil but are not locked in the radial direction of the assembly, longitudinally of the airfoil. The ribs may be bi-cast onto a preformed airfoil side wall structure or fastened to the airfoil by an interlocking slide connection and/or welding. By attaching the nozzle ribs to the nozzle airfoil metal in such a way that allows play longitudinally of the airfoil, the temperature difference induced radial thermal stresses at the nozzle airfoil/rib joint area are reduced while maintaining proper mechanical support of the nozzle side walls.

  12. [Differentiation of human and nonhuman primate ribs].

    PubMed

    May, E; Martins, M

    1985-01-01

    The ribs of 9 human beings and 6 animal-primates (4 Pongidae and 2 Cercopithecidae of 2 different species) had been examined metrically with regard to their relative dimensions and proportions. Special care was taken as well of the differentiation of single ribs of one individual as of interspecific differentiation. Generally the Pongidae show the greatest relative-dimensions. This concerns both the diameter as the length. The individuals of the genus Homo have medium-sized dimensions, while the Cercopithecidae have the smallest. In this way a first grouping of the measurements becomes possible. As for the rib-diameter Homo concurs more with the Pongidae than with the Cercopithecidae. At first from the rib-proportions resulted an indication to special similarity between the Pongidae and recent man from whom the Cercopithecidae distinctively differ as it is shown by the indices angulus-sternal end/tuberculum-angulus. A divariate presentation of the measurements of this index, however, proves that Homo concerning the single measurements occupies an intermediate position between the Pongidae and the Cercopithecidae in this case, too (Fig. 5). The examination of the craniocaudal trend of different ribmeasurements (length, depth and area of the rib-arc) produced a special similarity of the 4 upper ribs between the Pongidae and Homo. In the region of the lower chest a great conformity between the Pongidae and the Cercopithecidae became obvious in this respect. A different trend shows up in Homo - probably as an expression of the transformation-process in the human chest. The intraspecific morphometric discrimination of the single ribs proves to be especially difficult, above all between the 7th to 10th rib, if the ribs of an individual are not completely present. It is, however, possible in some cases by means of some measurements and indices of these ribs. PMID:4083514

  13. A rib-specific multimodal registration algorithm for fused unfolded rib visualization using PET/CT

    NASA Astrophysics Data System (ADS)

    Kaftan, Jens N.; Kopaczka, Marcin; Wimmer, Andreas; Platsch, Günther; Declerck, Jérôme

    2014-03-01

    Respiratory motion affects the alignment of PET and CT volumes from PET/CT examinations in a non-rigid manner. This becomes particularly apparent if reviewing fine anatomical structures such as ribs when assessing bone metastases, which frequently occur in many advanced cancers. To make this routine diagnostic task more efficient, a fused unfolded rib visualization for 18F-NaF PET/CT is presented. It allows to review the whole rib cage in a single image. This advanced visualization is enabled by a novel rib-specific registration algorithm that rigidly optimizes the local alignment of each individual rib in both modalities based on a matched filter response function. More specifically, rib centerlines are automatically extracted from CT and subsequently individually aligned to the corresponding bone-specific PET rib uptake pattern. The proposed method has been validated on 20 PET/CT scans acquired at different clinical sites. It has been demonstrated that the presented rib- specific registration method significantly improves the rib alignment without having to run complex deformable registration algorithms. At the same time, it guarantees that rib lesions are not further deformed, which may otherwise affect quantitative measurements such as SUVs. Considering clinically relevant distance thresholds, the centerline portion with good alignment compared to the ground truth improved from 60:6% to 86:7% after registration while approximately 98% can be still considered as acceptably aligned.

  14. WRAP-RIB antenna technology development

    NASA Technical Reports Server (NTRS)

    Freeland, R. E.; Garcia, N. F.; Iwamoto, H.

    1985-01-01

    The wrap-rib deployable antenna concept development is based on a combination of hardware development and testing along with extensive supporting analysis. The proof-of-concept hardware models are large in size so they will address the same basic problems associated with the design fabrication, assembly and test as the full-scale systems which were selected to be 100 meters at the beginning of the program. The hardware evaluation program consists of functional performance tests, design verification tests and analytical model verification tests. Functional testing consists of kinematic deployment, mesh management and verification of mechanical packaging efficiencies. Design verification consists of rib contour precision measurement, rib cross-section variation evaluation, rib materials characterizations and manufacturing imperfections assessment. Analytical model verification and refinement include mesh stiffness measurement, rib static and dynamic testing, mass measurement, and rib cross-section characterization. This concept was considered for a number of potential applications that include mobile communications, VLBI, and aircraft surveillance. In fact, baseline system configurations were developed by JPL, using the appropriate wrap-rib antenna, for all three classes of applications.

  15. Hemangioma of Rib: A Different Perspective

    PubMed Central

    Deshmukh, Hemant; Rathod, Kranti K.; Hira, Priya; Sankhe, Shilpa; Pandit, Nilesh; Mittal, Kartik; Dey, Amit K.

    2015-01-01

    Summary Background Hemangiomas are one of the common primary benign tumors of the intraosseous and soft tissue compartments in humans. Vertebral hemangiomas being the most common of all are seen in daily radiological practice. Hemangioma of the rib is rarely seen. Case Report We reported on a case of a rib lesion which had a classic imaging pattern of hemangioma. We highlighted the use of pre-operative embolization of such a vascular rib lesion before surgically removing the lesion by thoracotomy to reduce the risk of bleeding. Conclusions We also emphasized overt complications of overzealous needling of such a vascular lesion for histopathological diagnosis as in our case. PMID:25866595

  16. Wrap-rib antenna concept development overview

    NASA Technical Reports Server (NTRS)

    Woods, A. A., Jr.; Garcia, N. F.

    1983-01-01

    The wrap rib antenna design of a parabolic reflector large space antenna is discussed. Cost estimates, design/mission compatibility, deployment sequence, ground based tests, and fabrication are discussed.

  17. RIB Production at LNL: the EXOTIC Facility

    NASA Astrophysics Data System (ADS)

    Marco, Mazzocco

    2016-04-01

    Nuclear reactions involving radioactive isotopes are extremely relevant in several astrophysical scenarios, from the Big-Bang Nucleosynthesis to Supernovae explosions. In this contribution the production of Radioactive Ion Beams (RIBs) by means of the in-flight technique is reviewed. In particular, the use of direct reactions in inverse kinematics for the production of light weakly-bound RIBs by means of the facility EXOTIC at INFN-LNL (Italy) will be described in detail.

  18. Supersonic Wing Optimization Using SpaRibs

    NASA Technical Reports Server (NTRS)

    Locatelli, David; Mulani, Sameer B.; Liu, Qiang; Tamijani, Ali Y.; Kapania, Rakesh K.

    2014-01-01

    This research investigates the advantages of using curvilinear spars and ribs, termed SpaRibs, to design a supersonic aircraft wing-box in comparison to the use of classic design concepts that employ straight spars and ribs. The objective is to achieve a more efficient load-bearing mechanism and to passively control the deformation of the structure under the flight loads. Moreover, the use of SpaRibs broadens the design space and allows for natural frequencies and natural mode shape tailoring. The SpaRibs concept is implemented in a new optimization MATLAB-based framework referred to as EBF3SSWingOpt. This optimization scheme performs both the sizing and the shaping of the internal structural elements, connecting the optimizer with the analysis software. The shape of the SpaRibs is parametrically defined using the so called Linked Shape method. Each set of SpaRibs is placed in a one by one square domain of the natural space. The set of curves is subsequently transformed in the physical space for creating the wing structure geometry layout. The shape of each curve of each set is unique; however, mathematical relations link the curvature in an effort to reduce the number of design variables. The internal structure of a High Speed Commercial Transport aircraft concept developed by Boeing is optimized subjected to stress, subsonic flutter and supersonic flutter constraints. The results show that the use of the SpaRibs allows for the reduction of the aircraft's primary structure weight without violating the constraints. A weight reduction of about 15 percent is observed.

  19. Bilateral cervical ribs in a Dobermann Pinscher.

    PubMed

    Ricciardi, M; De Simone, A; Gernone, F; Giannuzzi, P

    2015-01-01

    An 11-year-old intact female Doberman Pinscher was presented with the complaint of non-ambulatory tetraparesis. Clinical and neurological examination revealed a caudal cervical spinal cord disfunction (C6-T2 spinal cord segments). Magnetic resonance imaging and computed tomographic (CT) findings of the cervical spine were consistent with caudal cervical spondylomyelopathy (CSM). During the diagnostic work-up for the cervical spine, bilateral bone anomalies involving the seventh cervical vertebra and the first ribs were found on radiographs and CT examination. The rib anomalies found in this dog appear similar to cervical ribs widely described in human medicine. In people, cervical ribs are associated with a high rate of stillbirth, early childhood cancer, and can cause the thoracic outlet syndrome, characterized by neurovascular compression at level of superior aperture of the chest. In dogs, only some sporadic anatomopathological descriptions of cervical ribs exist. In this report the radiographic and CT findings of these particular vertebral and rib anomalies along with their relationships with adjacent vasculature and musculature are shown intravitam in a dog. Specific radiographic and CT findings described in this report may help in reaching a presumptive diagnosis of this anomaly. Finally, their clinical and evolutionary significance are discussed. PMID:25650786

  20. Turbulent Heat Transfer in Ribbed Pipe Flow

    NASA Astrophysics Data System (ADS)

    Kang, Changwoo; Yang, Kyung-Soo

    2012-11-01

    From the view point of heat transfer control, surface roughness is one of the popular ways adopted for enhancing heat transfer in turbulent pipe flow. Such a surface roughness is often modeled with a rib. In the current investigation, Large Eddy Simulation has been performed for turbulent flow in a pipe with periodically-mounted ribs at Reτ=700, Pr=0.71, and p / k =2, 4, and 8. Here, p and k represent the pitch and rib height, respectively. The rib height is fixed as one tenth of the pipe radius. The profiles of mean velocity components, mean temperature, root-mean-squares (rms) of temperature fluctuation are presented at the selected streamwise locations. In comparison with the smooth-pipe case at the same Re and Pr, the effects of the ribs are clearly identified, leading to overall enhancement of turbulent heat transfer in terms of Nu. The budget of temperature variance is presented in the form of contours. The results of an Octant analysis are also given to elucidate the dominant events. Our LES results shed light on a complete understanding of the heat-transfer mechanisms in turbulent ribbed-pipe flow which has numerous applications in engineering. This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MEST) (No. 2012013019).

  1. Sliding Couette flow in a ribbed annulus

    NASA Astrophysics Data System (ADS)

    Moradi, H. V.; Floryan, J. M.

    2016-07-01

    The flow in an annulus driven by the axial movement of one of the cylinders has been studied. The stationary cylinder has been fitted with axisymmetric ribs resulting in the appearance of the centrifugal-force-driven instability which leads to the formation of axial vortices. The critical stability conditions have been determined for a wide range of geometries of practical interest; these conditions include the critical Reynolds number as well as the best vortex packing. It has been shown that a sufficiently large increase of the ribs' wavelength leads to a flow stabilization as the flow becomes nearly rectilinear, thus reducing the strength of the centrifugal force field. It has also been demonstrated that a sufficiently large decrease of the ribs' wavelength similarly results in the flow stabilization as the stream lifts up above the ribs' peaks and becomes more rectilinear. Reduction of the annulus' radius leads to qualitatively different flow responses depending on the position of the moving cylinder. The critical Reynolds number is reduced and the range of the ribs' wave numbers capable of inducing the instability is increased when the outer cylinder drives the flow. The trend is reversed when the inner cylinder drives the flow. Conditions when the ribbed cylinder is unable to induce any instability and, thus, behaves as a hydraulically smooth cylinder have been identified.

  2. Characterization of Human Rib Biomechanical Responses due to Three-Point Bending.

    PubMed

    Kalra, Anil; Saif, Tal; Shen, Ming; Jin, Xin; Zhu, Feng; Begeman, Paul; Yang, King H; Millis, Scott

    2015-11-01

    In the elderly population, rib fracture is one of the most common injuries sustained in motor vehicle crashes. The current study was conducted to predict the biomechanical fracture responses of ribs with respect to age, gender, height, weight and percentage of ash content. Three-point bending experiments were conducted on 278 isolated rib samples extracted from 82 cadaver specimens (53 males and 29 females between the ages of 21 and 87 years) for 6th and 7th levels of ribs. Statistical analyses were carried out to identify differences based on age and gender. It was found that, in comparison to males, females had significantly lower values for maximum bending moments, slopes of bending moment-angle curves, and average cortical-bone thickness (p<0.05). Samples of ribs taken from elderly specimens failed at lower values of fracture moments than those from younger specimens, and had lower slopes of bending moment-angle curves, both in males and females (p<0.05). The generalized estimated equations were developed to predict the values of biomechanical response and average cortical thickness based on age, gender, height and weight of individual specimens. Results from the current study illustrate that biomechanical responses and rib cortical thicknesses are functions of age, gender, height and weight. However, the current study is limited to a quasi-static loading scheme, which is different from real crash conditions. Hence, rib-material properties, which are dependent on strain rate, and are needed for wholebody finite element models representing different populations, still require more research. PMID:26660742

  3. The Role of Minimally Invasive Plate Osteosynthesis in Rib Fixation: A Review

    PubMed Central

    Bemelman, Michael; van Baal, Mark; Yuan, Jian Zhang; Leenen, Luke

    2016-01-01

    More than a century ago, the first scientific report was published about fracture fixation with plates. During the 1950’s, open reduction and plate fixation for fractures were standardized by the founders of Arbeitsgemeinschaft für osteosynthesefragen/Association for the Study of Internal Fixation. Since the introduction of plate fixation for fractures, several plates and screws have been developed, all with their own characteristics. To accomplice more fracture stability, it was thought the bigger the plate, the better. The counter side was a compromised blood supply of the bone, often resulting in bone necrosis and ultimately delayed or non-union. With the search and development of new materials and techniques for fracture fixation, less invasive procedures have become increasingly popular. This resulted in the minimally invasive plate osteosynthesis (MIPO) technique for fracture fixation. With the MIPO technique, procedures could be performed with smaller incisions and thus with less soft tissue damage and a better preserved blood supply. The last 5 years rib fixation has become increasingly popular, rising evidence has become available suggesting that surgical rib fixation improves outcome of patients with a flail chest or isolated rib fractures. Many surgical approaches for rib fixation have been described in the old literature, however, most of these techniques are obscure nowadays. Currently mostly large incisions with considerable surgical insult are used to stabilize rib fractures. We think that MIPO deserves a place in the surgical treatment of rib fractures. We present the aspects of diagnosis, preoperative planning and operative techniques in regard to MIPO rib fixation. PMID:26889439

  4. The RIB production target for the SPES project

    NASA Astrophysics Data System (ADS)

    Monetti, Alberto; Andrighetto, Alberto; Petrovich, Carlo; Manzolaro, Mattia; Corradetti, Stefano; Scarpa, Daniele; Rossetto, Francesco; Martinez Dominguez, Fernando; Vasquez, Jesus; Rossignoli, Massimo; Calderolla, Michele; Silingardi, Roberto; Mozzi, Aldo; Borgna, Francesca; Vivian, Gianluca; Boratto, Enrico; Ballan, Michele; Prete, Gianfranco; Meneghetti, Giovanni

    2015-10-01

    Facilities making use of the Isotope Separator On-Line (ISOL) method for the production of Radioactive Ion Beams (RIB) attract interest because they can be used for nuclear structure and reaction studies, astrophysics research and interdisciplinary applications. The ISOL technique is based on the fast release of the nuclear reaction products from the chosen target material together with their ionization into short-lived nuclei beams. Within this context, the SPES (Selective Production of Exotic Species) facility is now under construction in Italy at INFN-LNL (Istituto Nazionale di Fisica Nucleare — Laboratori Nazionali di Legnaro). The SPES facility will produce RIBs mainly from n-rich isotopes obtained by a 40 MeV cyclotron proton beam (200 μA) directly impinging on a uranium carbide multi-foil fission target. The aim of this work is to describe and update, from a comprehensive point of view, the most important results obtained by the analysis of the on-line behavior of the SPES production target assembly. In particular an improved target configuration has been studied by comparing different codes and physics models: the thermal analyses and the isotope production are re-evaluated. Then some consequent radioprotection aspects, which are essential for the installation and operation of the facility, are presented.

  5. Rib for blended wing-body aircraft

    NASA Technical Reports Server (NTRS)

    Hawley, Arthur V. (Inventor)

    1999-01-01

    Structural ribs for providing structural support for a structure, such as the pressure cabin of a blended-wing body aircraft. In a first embodiment, the ribs are generally Y-shaped, being comprised of a vertical web and a pair of inclined webs attached to the vertical web to extend upwardly and outwardly from the vertical web in different directions, with only the upper edges of the inclined webs being attached to a structural element. In a second embodiment, the ribs are generally trident-shaped, whereby the vertical web extends upwardly beyond the intersection of the inclined webs with the vertical web, with the upper edge of the vertical web as well as the upper edges of the inclined webs being attached to the same structural element.

  6. Offset wrap rib antenna concept development

    NASA Technical Reports Server (NTRS)

    Woods, A. A., Jr.

    1981-01-01

    A program to demonstrate large diameter offset reflector technology readiness through the development of ground testable, flight representative full size hardware also aims to provide a basis of data to allow confirmation of cost, performance, and size growth projections for the offset wrap ribe antenna design. An overview of the antenna system is presented and the operational deployment sequence examined. The ability to manufacture multiple segment ribs is assured and tooling for rib manufacture was redesigned to reduce cost. The selected mast design permits adequate stiffness and minimum stowed volume. Reflector and mast concerns and the program plan are summarized.

  7. 12. VIEW, LOOKING EAST, SHOWING CLOSEUP OF ORIGINAL RIBS OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. VIEW, LOOKING EAST, SHOWING CLOSEUP OF ORIGINAL RIBS OF THE VESSEL NEXT TO THE MORE MASSIVE NEW' RIBS - Motorized Sailing Vessel "Fox", Beached on East Bank ofBayou Lafourche, Larose, Lafourche Parish, LA

  8. Microtia reconstruction: autologous rib and alloplast techniques.

    PubMed

    Cabin, Jonathan A; Bassiri-Tehrani, Michael; Sclafani, Anthony P; Romo, Thomas

    2014-11-01

    Microtia represents a spectrum of maldevelopment of the external ear. Reconstructive techniques may utilize an autogenous rib cartilage framework and require 2-4 stages; alternatively, an alloplastic framework can be used and typically requires 1-2 stages. Successful reconstruction of microtia with either technique can provide a significant quality of life improvement, and both techniques are described in this article. PMID:25444733

  9. Offset weap rib concept and development

    NASA Technical Reports Server (NTRS)

    Woods, A. A., Jr.

    1980-01-01

    The applicability of the Wrap rib antenna design for offset feed configurations for antennas up to 300 m in diameter was assessed. The antenna design was defined for both symmetric and offset configurations in terms of surface quality, cost, weight, and mechanical complexity. A supporting deployable feed support structure was developed and characterized.

  10. Mechanical Action of the Intercostal Muscles on the Ribs

    NASA Astrophysics Data System (ADS)

    de Troyer, Andre; Kelly, Suzanne; Zin, Walter A.

    1983-04-01

    The external and internal interosseous intercostal muscles were separately stimulated at end-expiratory lung volume in anesthetized dogs. These muscles were all found to elevate the ribs into which they insert. By attaching weights to the ribs, it was determined that the nonlinear compliance of the ribs was responsible for this phenomenon.

  11. Method and apparatus for monitoring the thickness of a coal rib during rib formation

    DOEpatents

    Mowrey, Gary L.; Ganoe, Carl W.; Monaghan, William D.

    1996-01-01

    Apparatus for monitoring the position of a mining machine cutting a new entry in a coal seam relative to an adjacent, previously cut entry to determine the distance between a near face of the adjacent previously cut entry and a new face adjacent thereto of a new entry being cut by the mining machine which together define the thickness of a coal rib being formed between the new entry and the adjacent previously cut entry during the new entry-cutting operation. The monitoring apparatus; includes a transmit antenna mounted on the mining machine and spaced inwardly from the new face of the coal rib for transmitting radio energy towards the coal rib so that one portion of the radio energy is reflected by the new face which is defined at an air-coal interface between the new entry and the coal rib and another portion of the radio energy is reflected by the near face of the coal rib which is defined at an air-coal interface between the coal rib and the adjacent previously cut entry. A receive antenna mounted on the mining machine and spaced inwardly of the new face of the coal rib receives the one portion of the radio energy reflected by the new face and also receives the another portion of the radio energy reflected by the near face. A processor determines a first elapsed time period equal to the time required for the one portion of the radio energy reflected by the new face to travel between the transmit antenna and the receive antenna and also determines a second elapsed time period equal to the time required for the another portion of the radio energy reflected by the near face to travel between the transmit antenna and the receive antenna and thereafter calculates the thickness of the coal rib being formed as a function of the difference between the first and second elapsed time periods.

  12. Blunt Liver Injury with Intact Ribs under Impacts on the Abdomen: A Biomechanical Investigation

    PubMed Central

    Li, Zhengdong; Wan, Lei; Qin, Zhiqiang; Liu, Ningguo; Zhang, Jianhua; Zhong, Liangwei; Huang, Ping; Chen, Yijiu

    2013-01-01

    Abdominal trauma accounts for nearly 20% of all severe traffic injuries and can often result from intentional physical violence, from which blunt liver injury is regarded as the most common result and is associated with a high mortality rate. Liver injury may be caused by a direct impact with a certain velocity and energy on the abdomen, which may result in a lacerated liver by penetration of fractured ribs. However, liver ruptures without rib cage fractures were found in autopsies in a series of cases. All the victims sustained punches on the abdomen by fist. Many studies have been dedicated to determining the mechanism underlying hepatic injury following abdominal trauma, but most have been empirical. The actual process and biomechanism of liver injury induced by blunt impact on the abdomen, especially with intact ribs remained, are still inexhaustive. In order to investigate this, finite element methods and numerical simulation technology were used. A finite element human torso model was developed from high resolution CT data. The model consists of geometrically-detailed liver and rib cage models and simplified models of soft tissues, thoracic and abdominal organs. Then, the torso model was used in simulations in which the right hypochondrium was punched by a fist from the frontal, lateral, and rear directions, and in each direction with several impact velocities. Overall, the results showed that liver rupture was primarily caused by a direct strike of the ribs induced by blunt impact to the abdomen. Among three impact directions, a lateral impact was most likely to cause liver injury with a minimum punch speed of 5 m/s (the momentum was about 2.447 kg.m/s). Liver injuries could occur in isolation and were not accompanied by rib fractures due to different material characteristics and injury tolerance. PMID:23308111

  13. Chondral Rib Fractures in Professional American Football

    PubMed Central

    McAdams, Timothy R.; Deimel, Jay F.; Ferguson, Jeff; Beamer, Brandon S.; Beaulieu, Christopher F.

    2016-01-01

    Background: Although a recognized and discussed injury, chondral rib fractures in professional American football have not been previously reported in the literature. There currently exists no consensus on how to identify and treat these injuries or the expected return to play for the athlete. Purpose: To present 2 cases of chondral rib injuries in the National Football League (NFL) and discuss the current practice patterns for management of these injuries among the NFL team physicians. Study Design: Case series; Level of evidence, 4. Methods: Two cases of NFL players with chondral rib injuries are presented. A survey regarding work-up and treatment of these injuries was completed by team physicians at the 2014 NFL Combine. Our experience in identifying and treating these injuries is presented in conjunction with a survey of NFL team physicians’ experiences. Results: Two cases of rib chondral injuries were diagnosed by computed tomography (CT) and treated with rest and protective splinting. Return to play was 2 to 4 weeks. NFL Combine survey results show that NFL team physicians see a mean of 4 costal cartilage injuries per 5-year period, or approximately 1 case per year per team. Seventy percent of team physicians use CT scanning and 43% use magnetic resonance imaging for diagnosis of these injuries. An anesthetic block is used acutely in 57% and only electively in subsequent games by 39%. Conclusion: A high index of suspicion is necessary to diagnose chondral rib injuries in American football. CT scan is most commonly used to confirm diagnosis. Return to play can take up to 2 to 4 weeks with a protective device, although anesthetic blocks can be used to potentially expedite return. Clinical Relevance: Chondral rib injuries are common among NFL football players, while there is no literature to support proper diagnosis and treatment of these injuries or expected duration of recovery. These injuries are likely common in other contact sports and levels of

  14. Nuclear scan-guided rib biopsy

    SciTech Connect

    Moores, D.W.; Line, B.; Dziuban, S.W. Jr.; McKneally, M.F. )

    1990-04-01

    The bone scan is a sensitive screening device that is frequently used to stage the condition of patients with known or suspected malignant disease. Abnormal findings on bone scan are associated with corresponding normal findings on radiographs in approximately 50% of cases. Definitive tissue diagnosis of the bone lesion is often needed to determine optimal therapy, but localization of the lesion is imprecise unless it is palpable. Use of the nuclear scan to localize and mark the rib enhances the precision of the biopsy procedure. Thirty-three consecutive patients with cancer who had bone scans suggestive of rib abnormalities underwent nuclear scan-guided biopsy. Each patient had a repeat localizing scan with a maximum permissible dose of technetium 99m radionuclide on the day of the planned biopsy. The site of abnormality was marked with methylene blue injected into the skin overlying the lesion and down to the periosteum at the specific site. The patient was then taken to the operating room and the marked area was excised through a small incision. Pathologic abnormality was identified in all but one of the resected specimens, an accuracy rate of 97%. Despite a presumed or proved diagnosis of cancer in 33 patients, 16 specimens (48%) were benign. There were no complications associated with this technique, which reduces the morbidity and increases the precision of rib biopsy.

  15. Osteoradionecrosis of the Ribs following Breast Radiotherapy

    PubMed Central

    Nicholls, Luke; Gorayski, Peter; Harvey, Jennifer

    2015-01-01

    Introduction Osteoradionecrosis (ORN) of the chest wall is a rare complication after whole-breast radiotherapy (RT). Herein, we report a case of ORN involving the underlying ribs following adjuvant whole-breast RT using standard fractionation and conduct a review of the literature. Case Report A previously well 43-year-old female with right-sided, early-stage, node-negative breast cancer was treated with breast-conserving surgery. She subsequently underwent adjuvant whole-breast RT receiving 50 Gy in 25 fractions over 5 weeks using standard tangential photon fields with 6 MV photons followed by an electron boost of 10 Gy in 5 fractions according to International Commission on Radiation Units (ICRU) requirements. Eleven months after RT, the patient developed right lateral chest wall pain, with magnetic resonance imaging (MRI) demonstrating two fractures involving the underlying right fifth and sixth ribs associated with fatty marrow changes in the second to sixth ribs, thus raising the possibility of ORN. Treatments including hyperbaric oxygen, pentoxifylline and vitamin E were used with symptomatic improvements. There was demonstrable resolution on follow-up MRI at 2.5 years. Conclusion The incidence of ORN utilising modern RT techniques and standard fractionation is rare. Numerous treatments are available, with variable response rates. Emerging evidence of predictive gene profiling to estimate the risk of radiation sensitivity may assist in individualising preventative strategies to mitigate the risk of ORN. PMID:26351442

  16. Slipping Rib Syndrome as Persistent Abdominal and Chest Pain.

    PubMed

    Bolaños-Vergaray, Juan Javier; de la Gala García, Francisco; Obaya Rebollar, Juan Carlos; Bové Alvarez, Maria

    2015-11-01

    Slipping rib syndrome is an overlooked cause of persistent abdominal or chest pain. The etiology of this syndrome is not well understood, but the characteristic pain is from hypermobility of the false ribs. Although it is a diagnosis of exclusion, misdiagnosis may lead to an excessive workup. A simple clinical examination via the hooking maneuver is the most significant feature of its diagnosis. We describe the case of a 41-year-old woman with slipping rib syndrome. PMID:26528703

  17. Action of the diaphragm on the rib cage.

    PubMed

    Troyer, André De; Wilson, Theodore A

    2016-08-01

    When the diaphragm contracts, pleural pressure falls, exerting a caudal and inward force on the entire rib cage. However, the diaphragm also exerts forces in the cranial and outward direction on the lower ribs. One of these forces, the "insertional force," is applied by the muscle at its attachments to the lower ribs. The second, the "appositional force," is due to the transmission of abdominal pressure to the lower rib cage in the zone of apposition. In the control condition at functional residual capacity, the effects of these two forces on the lower ribs are nearly equal and outweigh the effect of pleural pressure, whereas for the upper ribs, the effect of pleural pressure is greater. The balance between these effects, however, may be altered. When the abdomen is given a mechanical support, the insertional and appositional forces are increased, so that the muscle produces a larger expansion of the lower rib cage and, with it, a smaller retraction of the upper rib cage. In contrast, at higher lung volumes the zone of apposition is decreased, and pleural pressure is the dominant force on the lower ribs as well. Consequently, although the force exerted by the diaphragm on these ribs remains inspiratory, rib displacement is reversed into a caudal-inward displacement. This mechanism likely explains the inspiratory retraction of the lateral walls of the lower rib cage observed in many subjects with chronic obstructive pulmonary disease (Hoover's sign). These observations support the use of a three-compartment, rather than a two-compartment, model to describe chest wall mechanics. PMID:27283911

  18. Primary Osteosarcoma of the Rib Identified on Bone Scintigraphy.

    PubMed

    Xie, Peng; Huang, Jianmin

    2016-05-01

    Osteosarcomas generally arise in appendicular skeletons, but rarely in the ribs. We described Tc-MDP bone scan findings from a 23-year-old man with right back pain. The images demonstrated elevated activity in the region overlapping the posterior 8th to 10th ribs and in the L9-10 vertebral bodies. CT showed an 8.8 × 8.3 cm mildly peripherally calcified mass arising from the right 10th rib involving the 9th and 10th thoracic vertebrae. Pathological examination confirmed primary osteosarcoma of the rib. PMID:26704734

  19. Eliminating rib shadows in chest radiographic images providing diagnostic assistance.

    PubMed

    Oğul, Hasan; Oğul, B Buket; Ağıldere, A Muhteşem; Bayrak, Tuncay; Sümer, Emre

    2016-04-01

    A major difficulty with chest radiographic analysis is the invisibility of abnormalities caused by the superimposition of normal anatomical structures, such as ribs, over the main tissue to be examined. Suppressing the ribs with no information loss about the original tissue would therefore be helpful during manual identification or computer-aided detection of nodules on a chest radiographic image. In this study, we introduce a two-step algorithm for eliminating rib shadows in chest radiographic images. The algorithm first delineates the ribs using a novel hybrid self-template approach and then suppresses these delineated ribs using an unsupervised regression model that takes into account the change in proximal thickness (depth) of bone in the vertical axis. The performance of the system is evaluated using a benchmark set of real chest radiographic images. The experimental results determine that proposed method for rib delineation can provide higher accuracy than existing methods. The knowledge of rib delineation can remarkably improve the nodule detection performance of a current computer-aided diagnosis (CAD) system. It is also shown that the rib suppression algorithm can increase the nodule visibility by eliminating rib shadows while mostly preserving the nodule intensity. PMID:26775736

  20. Detection and labeling ribs on expiration chest radiographs

    NASA Astrophysics Data System (ADS)

    Park, Mira; Jin, Jesse S.; Wilson, Laurence S.

    2003-06-01

    Typically, inspiration is preferred when xraying the lungs. The x-ray technologist will ask a patient to be still and to take a deep breath and to hold it. This not only reduces the possibility of a blurred image but also enhances the quality of the image since air-filled lungs are easier to see on x-ray film. However, inspiration causes low density in the inner part of lung field. That means that ribs in the inner part of lung field have lower density than the other parts nearer to the border of the lung field. That is why edge detection algorithms often fail to detect ribs. Therefore to make rib edges clear we try to produce an expiration lung field using a 'hemi-elliptical cavity.' Based on the expiration lung field, we extract the rib edges using canny edge detector and a new connectivity method, called '4 way with 10-neighbors connectivity' to detect clavicle and rib edge candidates. Once the edge candidates are formed, our system selects the best candidates using knowledge-based constraints such as a gradient, length and location. The edges can be paired and labeled as superior rib edge and inferior rib edge. Then the system uses the clavicle, which is obtained in a same method for the rib edge detection, as a landmark to label all detected ribs.

  1. Study of wrap-rib antenna design

    NASA Technical Reports Server (NTRS)

    Wade, W. D.; Sinha, A.; Singh, R.

    1979-01-01

    The results of a parametric design study conducted to develop the significant characteristics and technology limitations of space deployable antenna systems with aperture sizes ranging from 50 up to 300 m and F/D ratios between 0.5 and 3.0 are presented. Wrap/rib type reflectors of both the prime and offset fed geometry and associated feed support structures were considered. The significant constraints investigated as limitations on achievable aperture were inherent manufacturability, orbit dynamic and thermal stability, antenna weight, and antenna stowed volume. A data base, resulting in the defined maximum achievable aperture size as a function of diameter, frequency and estimated cost, was formed.

  2. Husbandry of Spanish ribbed newts (Pleurodeles waltl).

    PubMed

    Joven, Alberto; Kirkham, Matthew; Simon, András

    2015-01-01

    Research on urodele amphibians, such as newts, is constantly contributing to our understanding of fundamental biological processes. In the present chapter, we present detailed husbandry protocols for the Spanish ribbed newt (Pleurodeles waltl ). We describe the main phases of their life cycle, with emphasis on the progressive development of sensory, motor, and integration systems, which lead to the acquisition of specific stereotyped (and conditioned) behaviors. The methods are outlined to manage housing, feeding, handling, captive breeding, health monitoring, and euthanasia in this species under laboratory conditions. With minor changes, these protocols can also be applied to other species of urodele amphibians commonly used in laboratory research. PMID:25740476

  3. CT observation of rib abnormalities: spectrum of findings.

    PubMed

    Edelstein, G; Levitt, R G; Slaker, D P; Murphy, W A

    1985-01-01

    The CT studies in 63 patients in which rib abnormality was identified or excluded were retrospectively analyzed. The CT features were detailed and correlated with other available radiographic findings as well as clinical data. Contiguous spread of tumor to rib or metastasis to rib characteristically showed subtle or complete segmental lytic rib destruction. An accompanying extrapleural soft tissue mass was frequently seen with metastatic disease and myeloma. In nine patients CT showed rib destruction that had been obscured on chest radiography by heart, diaphragm, mass, or pleural effusion. Other imaging studies prompted consideration of neoplasm in seven patients in whom CT clearly showed benign post-traumatic or developmental lesions. Six patients had a clinically suspected chest wall mass excluded, leading to the diagnosis of Tietze syndrome. The ribs should be carefully inspected on all CT studies of the thorax and upper abdomen. Computed tomography is helpful when other imaging techniques, such as rib films or isotopic bone scans, have not resolved the question of clinically or radiographically suspected rib abnormality. PMID:3968282

  4. Tapered rib fiber coupler for semiconductor optical devices

    DOEpatents

    Vawter, Gregory A.; Smith, Robert Edward

    2001-01-01

    A monolithic tapered rib waveguide for transformation of the spot size of light between a semiconductor optical device and an optical fiber or from the fiber into the optical device. The tapered rib waveguide is integrated into the guiding rib atop a cutoff mesa type semiconductor device such as an expanded mode optical modulator or and expanded mode laser. The tapered rib acts to force the guided light down into the mesa structure of the semiconductor optical device instead of being bound to the interface between the bottom of the guiding rib and the top of the cutoff mesa. The single mode light leaving or entering the output face of the mesa structure then can couple to the optical fiber at coupling losses of 1.0 dB or less.

  5. High-efficiency target-ion sources for RIB generation

    SciTech Connect

    Alton, G.D.

    1993-12-31

    A brief review is given of high-efficiency ion sources which have been developed or are under development at ISOL facilities which show particular promise for use at existing, future, or radioactive ion beam (RIB) facilities now under construction. Emphasis will be placed on those sources which have demonstrated high ionization efficiency, species versatility, and operational reliability and which have been carefully designed for safe handling in the high level radioactivity radiation fields incumbent at such facilities. Brief discussions will also be made of the fundamental processes which affect the realizable beam intensities in target-ion sources. Among the sources which will be reviewed will be selected examples of state-of-the-art electron-beam plasma-type ion sources, thermal-ionization, surface-ionization, ECR, and selectively chosen ion source concepts which show promise for radioactive ion beam generation. A few advanced, chemically selective target-ion sources will be described, such as sources based on the use of laser-resonance ionization, which, in principle, offer a more satisfactory solution to isobaric contamination problems than conventional electromagnetic techniques. Particular attention will be given to the sources which have been selected for initial or future use at the Holifield Radioactive Ion Beam Facility now under construction at the Oak Ridge National Laboratory.

  6. Nuclear Physics with RIB's: How it all started

    NASA Astrophysics Data System (ADS)

    Tanihata, Isao

    2016-04-01

    Neutron halos were discovered through measurements of interaction cross sections and fragmentation cross sections of nuclei near the neutron drip line. Such measurements became possible with the use of radioactive ion beams (RIBs) produced though projectile fragmentations of high-energy heavy-ion collisions. RIBs were invented 30 years ago at the Bevalac facility in Berkeley. In this article, I describe how they were invented and how neutron halos were discovered. What happened at that time was a series of small serendipities guiding us to the present prosperous field of RIB science.

  7. Structural efficiency study of graphite-epoxy aircraft rib structures

    NASA Technical Reports Server (NTRS)

    Swanson, Gary D.; Gurdal, Zafer; Starnes, James H., Jr.

    1988-01-01

    Attention is given to the structural efficiencies obtainable with optimally designed graphite/epoxy wing rib panel configurations that are potentially economically manufacturable. Some ribs are commonly used as fuel cell closeout panels, and are accordingly subjected to out-of-plane pressure loads in addition to the in-plane axial compressive and shear loads resulting from the wing loading. The present minimum-weight panel designs satisfy buckling and strength constraints for wing rib panels subjected to a wide range of combined load conditions.

  8. Periodically developed flow and heat transfer in a ribbed duct

    NASA Astrophysics Data System (ADS)

    Acharya, S.; Dutta, S.; Myrum, T. A.; Baker, R. S.

    1993-05-01

    Periodic fully developed flow and heat transfer results for a ribbed duct were obtained experimentally and numerically, using the nonlinear and standard k-epsilon turbulence models. Predicted recirculation lengths and maximum Nusselt number locations agreed well with the measured values. Both models performed poorly in the separated region just behind the ribs, where the Reynolds stresses were grossly underpredicted, the flow temperatures were overpredicted, and the mean velocity magnitudes were generally underpredicted. The local Nusselt numbers were underpredicted by both models. The nonlinear model predicted more realistic Reynolds stresses in the core flow region immediately above the ribs than the standard k-epsilon model.

  9. 30 CFR 75.202 - Protection from falls of roof, face and ribs.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Protection from falls of roof, face and ribs... Protection from falls of roof, face and ribs. (a) The roof, face and ribs of areas where persons work or... roof, face or ribs and coal or rock bursts. (b) No person shall work or travel under unsupported...

  10. 30 CFR 75.202 - Protection from falls of roof, face and ribs.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Protection from falls of roof, face and ribs... Protection from falls of roof, face and ribs. (a) The roof, face and ribs of areas where persons work or... roof, face or ribs and coal or rock bursts. (b) No person shall work or travel under unsupported...

  11. 30 CFR 75.202 - Protection from falls of roof, face and ribs.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Protection from falls of roof, face and ribs... Protection from falls of roof, face and ribs. (a) The roof, face and ribs of areas where persons work or... roof, face or ribs and coal or rock bursts. (b) No person shall work or travel under unsupported...

  12. 16. OBLIQUE VIEW OF UNDERSTRUCTURE, SHOWING NORTH PIER, ARCH RIBS, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. OBLIQUE VIEW OF UNDERSTRUCTURE, SHOWING NORTH PIER, ARCH RIBS, COLUMNS, AND SWAY BRACING, LOOKING SOUTH - Chili Bar Bridge, Spanning South Fork of American River at State Highway 193, Placerville, El Dorado County, CA

  13. 18. VIEW OF UNDERSTRUCTURE, SHOWING ARCH RIBS, COLUMNS, AND SWAY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. VIEW OF UNDERSTRUCTURE, SHOWING ARCH RIBS, COLUMNS, AND SWAY BRACING, LOOKING SOUTHWEST FROM NORTH ABUTMENT - Chili Bar Bridge, Spanning South Fork of American River at State Highway 193, Placerville, El Dorado County, CA

  14. Vibration characteristics of hexagonal radial rib and hoop platforms

    NASA Technical Reports Server (NTRS)

    Belvin, W. K.

    1983-01-01

    Experiment and analysis have been used to characterize the modes of vibration of planar radial rib and hoop hexagonal platforms. Finite element analysis correlated very well with experimental results. The sensitivity of mode shapes and frequencies to cable stiffness and initial tension is presented. Threshold values have been identified, above which changes in cable stiffness do not affect the first few platform vibration modes. Primary vibration modes of the radial rib platform involve beam bending. Vibration modes of the hoop platform exhibit both beam bending and frame bending and torsion. Results indicate for low order polygonal structures, the radial rib concept produced a higher fundamental frequency. For high order polygonal structures, the hoop concept has the potential to achieve a higher fundamental frequency than the radial rib concept.

  15. 4. VIEW LOOKING ENE OF UNDERSIDE SHOWING RIBS AND BEAMS. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. VIEW LOOKING ENE OF UNDERSIDE SHOWING RIBS AND BEAMS. NOTE SPALLING ON NORTHERN EDGE AND EXPOSED REBAR. - Morris Run Bridge, Rickert Road (TR 417) spanning Morris Run in Hilltown Township, Dublin, Bucks County, PA

  16. Detail, center pier, showing rigidlyfixed arch ribs, starpattern balustrade, and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail, center pier, showing rigidly-fixed arch ribs, star-pattern balustrade, and simple ornamentation including molded treatment of concrete, pyramidal pier cap, and stylized pilaster - Horner Street Bridge, Horner Street over Stonycreek River, Johnstown, Cambria County, PA

  17. 18. Understructure, view of south arch abutment showing arch ribs, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. Understructure, view of south arch abutment showing arch ribs, columns, sway bracing, floor beams, deck cantilever, railing; view to southwest. - Parks Bar Bridge, Spanning Yuba River at State Highway 20, Smartville, Yuba County, CA

  18. 11. DETAIL OF WEST WEB, FROM STREAMBANK, SHOWING ARCH RIB, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. DETAIL OF WEST WEB, FROM STREAMBANK, SHOWING ARCH RIB, HANGERS, FLOOR BEAMS AND GUARDRAIL. VIEW TO NORTHEAST. - Rock Valley Bridge, Spanning North Timber Creek at Old U.S. Highway 30, Marshalltown, Marshall County, IA

  19. 9. DETAIL OF EAST ARCH, FROM ROADWAY, SHOWING ARCH RIB, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. DETAIL OF EAST ARCH, FROM ROADWAY, SHOWING ARCH RIB, ARTICULATED HANGER AND GUARDRAIL. VIEW TO SOUTHEAST. - Rock Valley Bridge, Spanning North Timber Creek at Old U.S. Highway 30, Marshalltown, Marshall County, IA

  20. 12. DETAIL OF NORTH ABUTMENT, FROM BENEATH, SHOWING ARCH RIB ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. DETAIL OF NORTH ABUTMENT, FROM BENEATH, SHOWING ARCH RIB AND FLOOR BEAM. VIEW TO NORTHEAST. - Rock Valley Bridge, Spanning North Timber Creek at Old U.S. Highway 30, Marshalltown, Marshall County, IA

  1. 10. DETAIL OF WEST ARCH, FROM ROADWAY, SHOWING ARCH RIB, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. DETAIL OF WEST ARCH, FROM ROADWAY, SHOWING ARCH RIB, HANGERS AND GUARDRAIL. VIEW TO SOUTH. - Rock Valley Bridge, Spanning North Timber Creek at Old U.S. Highway 30, Marshalltown, Marshall County, IA

  2. 1. VIEW, LOOKING NORTHEAST, SHOWING RIBS AND KEELSON OF HULL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. VIEW, LOOKING NORTHEAST, SHOWING RIBS AND KEELSON OF HULL IN CENTER OF PICTURE ON SHINGLE BEACH Charles Wisniewski, photographer, January 1985 - Shooters Island, Ships Graveyard, Vessel No. 84, Newark Bay, Staten Island (subdivision), Richmond County, NY

  3. Rib fractures in coronary bypass patients: radionuclide detection

    SciTech Connect

    Greenwald, L.V.; Baisden, C.E.; Symbas, P.N.

    1983-08-01

    Sternal retraction can cause the first rib to be fractured posteriorly, injuring the brachial plexus. The authors conducted bone scans of 24 consecutive open-heart surgery patients and found an unexpectedly high number of rib fractures which in all but one case had not been seen on the chest radiograph. Bone scans are recommended whenever there is unexplained non-incisional pain in a patient who has undergone sternal retraction.

  4. Lower thoracic rib stress fractures in baseball pitchers.

    PubMed

    Gerrie, Brayden J; Harris, Joshua D; Lintner, David M; McCulloch, Patrick C

    2016-01-01

    Stress fractures of the first rib on the dominant throwing side are well-described in baseball pitchers; however, lower thoracic rib fractures are not commonly recognized. While common in other sports such as rowing, there is scant literature on these injuries in baseball. Intercostal muscle strains are commonly diagnosed in baseball pitchers and have a nearly identical presentation but also a highly variable healing time. The diagnosis of a rib stress fracture can predict a more protracted recovery. This case series presents two collegiate baseball pitchers on one team during the same season who were originally diagnosed with intercostal muscle strains, which following magnetic resonance imaging (MRI) were found to have actually sustained lower thoracic rib stress fractures. The first sustained a stress fracture of the posterior aspect of the right 8th rib on the dominant arm side, while the second presented with a left-sided 10th rib stress fracture on the nondominant arm side. In both cases, MRI was used to visualize the fractures as plain radiographs are insensitive and commonly negative early in patient presentation. Patients were treated with activity modification, and symptomatic management for 4-6 weeks with a graduated return to throwing and competition by 8-10 weeks. The repetitive high stresses incurred by pitching may cause either dominant or nondominant rib stress fractures and this should be included in the differential diagnosis of thoracic injuries in throwers. It is especially important that athletic trainers and team physicians consider this diagnosis, as rib fractures may have a protracted course and delayed return to play. Additionally, using the appropriate imaging techniques to establish an accurate diagnosis can help inform return-to-play decisions, which have important practical applications in baseball, such as roster management and eligibility. PMID:26559562

  5. Buckling Tests with a Spar-rib Grill

    NASA Technical Reports Server (NTRS)

    Weinhold, Josef

    1940-01-01

    The present report deals with a comparison of mathematically and experimentally defined buckling loads of a spar-rib grill, on the assumption of constant spar section, and infinitely closely spaced ribs with rigidity symmetrical to the grill center. The loads are applied as equal bending moments at both spar ends, as compression in the line connecting the joints, and in the spar center line as the assumedly uniformly distributed spar weight.

  6. New technique for fixing rib fracture with bioabsorbable plate.

    PubMed

    Oyamatsu, Hironori; Ohata, Norihisa; Narita, Kunio

    2016-09-01

    Fixation of a bone fracture with a bioabsorbable plate made of poly-L-lactide and hydroxyapatite has received attention. We adopted this technique for a rib fracture by bending the plate into a U-shape and fixing it with suture through the holes in the mesh of the plate and holes that are drilled in the edge of the fractured rib. The suture is also wound around the plate. PMID:27206779

  7. Nasal reconstruction with articulated irradiated rib cartilage

    SciTech Connect

    Murakami, C.S.; Cook, T.A.; Guida, R.A. )

    1991-03-01

    Nasal structural reconstruction is a formidable task in cases where there is loss of support to both the nasal dorsum and tip. A multitude of surgical approaches and materials have been used for the correction of the saddle-nose deformity with varying degrees of success. Articulated irradiated rib cartilage inserted through an external rhinoplasty approach was used to reconstruct nasal deformities in 18 patients over a 6-year period. Simultaneous use of a midline forehead flap to reconstruct the overlying soft tissue was required in four cases. Follow-up ranged from 1 to 6 years (mean, 2.8 years). Results were rewarding in most cases with marked improvement in nasal support and airway. Revision and/or replacement secondary to trauma or warping of the graft was required in four cases. None of the patients exhibited infection, extrusion, or noticeable resorption. A description of the surgical technique, review of all the cases, and recommendation for continued use of this graft material are discussed.

  8. VTT's micron-scale silicon rib+strip waveguide platform

    NASA Astrophysics Data System (ADS)

    Aalto, Timo; Harjanne, Mikko; Cherchi, Matteo

    2016-05-01

    Silicon rib waveguides enable single-mode (SM) operation even with the combination of multi-micron core dimensions and high refractive index contrast. In such large waveguides the optical mode field is almost completely confined inside the Si core, which leads to small propagation losses and small polarization dependency. The unique SM condition of the rib waveguide also enables the use of an ultra-wide wavelength range, for example from 1.2 to <1.7 μm, without sacrificing either SM operation or low propagation loss. This makes micron-scale Si waveguides particularly well-suited for spectroscopy and extensive wavelength division multiplexing. However, rib waveguides require large bending radii, which lead to large circuit sizes. There are two solutions for this. So-called Euler bends in Si strip waveguides enable low-loss bends down to 1 μm bending radius with less than 0.1 dB/90° loss for both polarizations. Another alternative is a total-internal reflection mirror that can have loss as low as 0.1 dB for both polarizations in either strip or rib waveguides. The excitation of higher order modes in large strip waveguides is avoided by using adiabatic rib-strip converters and low-loss components. With rib and strip waveguides it is possible to reach a unique combination of low loss, extremely small footprint, small polarization dependency, ultra-wide bandwidth and tolerance to high optical powers.

  9. Optimal Topology of Aircraft Rib and Spar Structures under Aeroelastic Loads

    NASA Technical Reports Server (NTRS)

    Stanford, Bret K.; Dunning, Peter D.

    2014-01-01

    Several topology optimization problems are conducted within the ribs and spars of a wing box. It is desired to locate the best position of lightening holes, truss/cross-bracing, etc. A variety of aeroelastic metrics are isolated for each of these problems: elastic wing compliance under trim loads and taxi loads, stress distribution, and crushing loads. Aileron effectiveness under a constant roll rate is considered, as are dynamic metrics: natural vibration frequency and flutter. This approach helps uncover the relationship between topology and aeroelasticity in subsonic transport wings, and can therefore aid in understanding the complex aircraft design process which must eventually consider all these metrics and load cases simultaneously.

  10. Microgravity alters respiratory abdominal and rib cage motion during sleep

    PubMed Central

    Prisk, G. Kim; Paiva, Manuel

    2009-01-01

    The abdominal and rib cage contributions to tidal breathing differ between rapid-eye-movement (REM) and non-NREM sleep. We hypothesized that abdominal relative contribution during NREM and REM sleep would be altered in different directions when comparing sleep on Earth with sleep in sustained microgravity (μG), due to conformational changes and differences in coupling between the rib cage and the abdominal compartment induced by weightlessness. We studied respiration during sleep in five astronauts before, during, and after two Space Shuttle missions. A total of 77 full-night (8 h) polysomnographic studies were performed; abdominal and rib cage respiratory movements were recorded using respiratory inductive plethysmography. Breath-by-breath analysis of respiration was performed for each class: awake, light sleep, deep sleep, and REM sleep. Abdominal contribution to tidal breathing increased in μG, with the first measure in space being significantly higher than preflight values, followed by a return toward preflight values. This was observed for all classes. Preflight, rib cage, and abdominal movements were found to be in phase for all but REM sleep, for which an abdominal lead was observed. The abdominal leading role during REM sleep increased while deep sleep showed the opposite behavior, the rib cage taking a leading role in-flight. In μG, the percentage of inspiratory time in the overall breath, the duty cycle (TI/TTot), decreased for all classes considered when compared with preflight, while normalized inspiratory flow, taking the awake values as reference, increased in-flight for light sleep, deep sleep, and REM. Changes in abdominal-rib cage displacements probably result from a less efficient operating point for the diaphragm and a less efficient coupling between the abdomen and the apposed portion of the rib cage in μG. However, the preservation of total ventilation suggests that short-term adaptive mechanisms of ventilatory control compensate for these

  11. Prediction of Heat and Mass Transfer in a Rotating Ribbed Coolant Passage With a 180 Degree Turn

    NASA Technical Reports Server (NTRS)

    Rigby, David L.

    1999-01-01

    Numerical results are presented for flow in a rotating internal passage with a 180 degree turn and ribbed walls. Reynolds numbers ranging from 5200 to 7900, and Rotation numbers of 0.0 and 0.24 were considered. The straight sections of the channel have a square cross section, with square ribs spaced one hydraulic diameter (D) apart on two opposite sides. The ribs have a height of 0.1D and are not staggered from one side to the other. The full three dimensional Reynolds Averaged Navier-Stokes equations are solved combined with the Wilcox k-omega turbulence model. By solving an additional equation for mass transfer, it is possible to isolate the effect of buoyancy in the presence of rotation. That is, heat transfer induced buoyancy effects can be eliminated as in naphthalene sublimation experiments. Heat transfer, mass transfer and flow field results are presented with favorable agreement with available experimental data. It is shown that numerically predicting the reattachment between ribs is essential to achieving an accurate prediction of heat/mass transfer. For the low Reynolds numbers considered, the standard turbulence model did not produce reattachment between ribs. By modifying the wall boundary condition on omega, the turbulent specific dissipation rate, much better agreement with the flow structure and heat/ mass transfer was achieved. It is beyond the scope of the present work to make a general recommendation on the omega wall boundary condition. However, the present results suggest that the omega boundary condition should take into account the proximity to abrupt changes in geometry.

  12. At grade optical crossover for monolithic optial circuits

    NASA Technical Reports Server (NTRS)

    Jamieson, Robert S. (Inventor)

    1983-01-01

    Planar optical circuits may be made to cross through each other, (thus eliminating extra steps required to fabricate elevated, nonintersecting crossovers) by control of the dimensions of the crossing light conductors (10, 12) to be significantly greater than d=0.89.lambda. and the angle of crossing as nearly 90.degree. as conveniently possible. A light trap may be provided just ahead of the intersection to trap any light being reflected in the source conductor at angles greater than about 45.degree.. The light trap may take the form of triangular shaped portions (16a, 16b) on each side of the source conductor with the far side of the triangular portion receiving incident light at an angle so that incident light will be reflected to the other side, or it may take the form of windows (18a, 18b) in place of the triangular portions. Planar optical circuit boards (21-23) may be fabricated and stacked to form a keyboard (20) with intersecting conductors (26-29) and keyholes (0-9) where conductors merge at the broad side of the circuit boards. These keyholes may be prearranged to form an array or matrix of keyholes.

  13. Muscle: Bone ratios in beef rib sections.

    PubMed

    Dolezal, H G; Murphey, C E; Smith, G C; Carpenter, Z L; McCartor, M

    1982-01-01

    Thirty-eight steers and thirty heifers (14 to 17 months of age, from F(1) Hereford × Brahman cows bred to Angus or Hereford bulls), were either forage-fed for 123 days on millet-bermudagrass pasture or grain-fed for 90 days on a high-concentrate diet and were then commercially slaughtered. Warm carcass weights ranged from 167·8 kg to 324·3 kg. At 24 h post mortem, Texas Agricultural Experiment Station personnel (1) assigned scores or took measurements on each carcass for all factors used in yield grading and quality grading, (2) measured the length of hind leg (HL) and carcass length (CL) and (3) assigned a score for carcass muscling (MS) and, as appropriate, made an adjusted longissimus muscle area (ALA) evaluation. The 9th-10th-11th rib section from one side of each carcass was physically separated into longissimus muscle, fat, 'other soft tissue' and bone and ether extract determinations of the longissimus muscle and 'other soft tissue' components were made and used to adjust the yields of each of these components to a fat-free basis. Muscle to bone ratios ranged from 2·38 to 4·37. With both age and carcass weight held constant, diet, breed and sex explained only 35·8% of the variation in muscle to bone ratio. The best simple correlation with muscle to bone ratio was ALA/CL (r = ·59). Other measures significantly correlated with muscle to bone ratio included ALA (r = 0·55), MS (r = 0·50) and carcass weight (r = 0·49). Multiple regression analyses identified a three-variable subset comprised of ALA, carcass weight and CL which was related (P < 0·01) to muscle to bone ratio R(2) = 0·41). Data suggest that muscle to bone ratios differ widely among beef carcasses of similar genetic-management history and that there are carcass measures useful for predicting muscle to bone ratio. PMID:22054706

  14. Triode carbon nanotube field emission display using barrier rib structure and manufacturing method thereof

    DOEpatents

    Han, In-taek; Kim, Jong-min

    2003-01-01

    A triode carbon nanotube field emission display (FED) using a barrier rib structure and a manufacturing method thereof are provided. In a triode carbon nanotube FED employing barrier ribs, barrier ribs are formed on cathode lines by a screen printing method, a mesh structure is mounted on the barrier ribs, and a spacer is inserted between the barrier ribs through slots of the mesh structure, thereby stably fixing the mesh structure and the spacer within a FED panel due to support by the barrier ribs.

  15. Process for fabricating ribbed electrode substrates and other articles

    DOEpatents

    Goller, Glen J.; Breault, Richard D.; Smith, J. Harold

    1984-01-01

    A process for fabricating a resin bonded carbon fiber article, and in particular electrochemical cell electrode substrates and the like requiring different mean pore sizes in different areas, involves simultaneously heating and compacting different mixtures of carbon fibers and resin in different areas of an article forming mold, wherein the carbon fibers in each of the different mixtures have different, known bulk densities. The different bulk densities of the carbon fibers in the mixtures are chosen to yield the desired mean pore sizes and other properties in the article after heating and compacting the mixtures. Preferably, the different bulk densities are obtained using different carbon fiber lengths in the molding mixtures. The process is well suited to forming ribbed electrode substrates with preselected optimum mean pore sizes, porosities, and densities in the ribs, the webs connecting the ribs, and in the edge seals.

  16. Stress fracture of the rib in an elite oarsman.

    PubMed

    McKenzie, D C

    1989-06-01

    This paper documents an unusual case of a stress fracture of the ninth rib in an elite oarsman. A 25-year-old male presented with a 3-day history of right-sided chest pain aggravated by deep inspiration and movements simulating rowing. The athlete was treated initially as having a soft tissue injury; however, a technetium-99 bone scan confirmed the diagnosis. Routine radiographs of the ribs were negative. The pain and symptoms were confined to the anatomical area of the fracture along the anterolateral portion of the rib where the serratus anterior muscle originates. An analysis of the stroke mechanics involved in rowing implicated the serratus anterior muscle as being a major contributor to the repetitive stress that resulted in the injury. The primary etiological factor was errors in the training program. The athlete responded to simple conservative measures and was able to return to competitive rowing in 1 month's time. PMID:2777439

  17. Rib butterfly fractures as a possible indicator of blast trauma.

    PubMed

    Christensen, Angi M; Smith, Victoria A

    2013-01-01

    Forensic anthropologists have become increasingly involved in the interpretation of skeletal trauma caused by exploding ordnance. This study examines the cause and significance of butterfly fractures observed in a recent study investigating skeletal blast trauma by Christensen et al. Fractured ribs resulting from blast events carried out in the original study were re-examined revealing that rib butterfly fractures with the tensile indicator on the visceral surface were present in 100% of viable pig specimens. Additionally, manual fracture testing was performed on 46 pig ribs to simulate the bending force believed to have been sustained in the original blast events. Fracture testing resulted in 93% of specimens presenting butterfly fractures with the tensile indicator on the visceral surface. This fracture pattern differs significantly from that normally observed in association with other types of trauma events and may aid forensic anthropologists and other investigators in the identification and interpretation of blast events. PMID:23126284

  18. Free rib graft reconstruction of the mandible: a forgotten option?

    PubMed Central

    Banerjee, A. R.; Westmore, G. A.

    1995-01-01

    Eleven patients underwent primary mandibular reconstruction following resection of a head and neck squamous cell carcinoma. Reconstruction consisted of a free rib graft and a pectoralis major myocutaneous flap. One rib graft failed and one graft, although successful, required removal during a wider resection for tumour recurrence. A further three patients have died since operation, two from tumour recurrence and one from unrelated medical causes. Six patients have undergone long-term follow-up of between 22 and 78 months with a mean of 51 months. They have oral continence, take a normal or semisolid diet, and have satisfactory cosmesis. We present the first long-term follow-up of a series of patients undergoing mandibular reconstruction with a free rib graft and pectoralis major myocutaneous flap. Images Figure 1 Figure 2 PMID:7574320

  19. Numerical investigations of rib fracture failure models in different dynamic loading conditions.

    PubMed

    Wang, Fang; Yang, Jikuang; Miller, Karol; Li, Guibing; Joldes, Grand R; Doyle, Barry; Wittek, Adam

    2016-01-01

    Rib fracture is one of the most common thoracic injuries in vehicle traffic accidents that can result in fatalities associated with seriously injured internal organs. A failure model is critical when modelling rib fracture to predict such injuries. Different rib failure models have been proposed in prediction of thorax injuries. However, the biofidelity of the fracture failure models when varying the loading conditions and the effects of a rib fracture failure model on prediction of thoracic injuries have been studied only to a limited extent. Therefore, this study aimed to investigate the effects of three rib failure models on prediction of thoracic injuries using a previously validated finite element model of the human thorax. The performance and biofidelity of each rib failure model were first evaluated by modelling rib responses to different loading conditions in two experimental configurations: (1) the three-point bending on the specimen taken from rib and (2) the anterior-posterior dynamic loading to an entire bony part of the rib. Furthermore, the simulation of the rib failure behaviour in the frontal impact to an entire thorax was conducted at varying velocities and the effects of the failure models were analysed with respect to the severity of rib cage damages. Simulation results demonstrated that the responses of the thorax model are similar to the general trends of the rib fracture responses reported in the experimental literature. However, they also indicated that the accuracy of the rib fracture prediction using a given failure model varies for different loading conditions. PMID:26214136

  20. Mutagenesis in Newts: Protocol for Iberian Ribbed Newts.

    PubMed

    Hayashi, Toshinori; Takeuchi, Takashi

    2016-01-01

    Newts have the remarkable capability of organ/tissue regeneration, and have been used as a unique experimental model for regenerative biology. The Iberian ribbed newt (Pleurodeles waltl) is suitable as a model animal. We have established methods for artificial insemination and efficient transgenesis using P. waltl newts. In addition to the transgenic technique, development of TALENs enables targeting mutagenesis in the newts. We have reported that TALENs efficiently disrupted targeted genes in newt embryos. In this chapter, we introduce a protocol for TALEN-mediated gene targeting in Iberian ribbed newts. PMID:26443218

  1. The Diverging Sphere and the Rib in Prompt Detonation

    SciTech Connect

    Souers, P C; McGuire, E; Garza, R; Roeske, F; Vitello, P

    2002-05-03

    Steady state corner-turning in the rib is possible if R{sub 0}/R{sub 1} << 0.15, where R{sub 0} is the half-width and R{sub 1} the inner radius. For thicker ribs, the kinetics will further slow the turn. A steady state turn will have a symmetrical detonation front. The inverse radius relation appears to hold for the diverging sphere, at least for large radii. The reaction zone lengths for diverging spheres and ratesticks increase with the radius of curvature and are comparable.

  2. 21. Detail of steel ribs at south wall, T18; Note ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    21. Detail of steel ribs at south wall, T-18; Note composition of ribs--two steel channels welded together - Advance Base Depot Davisville, Building T-17, Ninth Street southeast of Davisville Road, Davisville, Washington County, RI

  3. Microbiological Safety of Commercial Prime Rib Preparation Methods: Thermal Inactivation of Salmonella in Mechanically Tenderized Rib Eye.

    PubMed

    Calle, Alexandra; Porto-Fett, Anna C S; Shoyer, Bradley A; Luchansky, John B; Thippareddi, Harshavardhan

    2015-12-01

    Boneless beef rib eye roasts were surface inoculated on the fat side with ca. 5.7 log CFU/g of a five-strain cocktail of Salmonella for subsequent searing, cooking, and warm holding using preparation methods practiced by restaurants surveyed in a medium-size Midwestern city. A portion of the inoculated roasts was then passed once through a mechanical blade tenderizer. For both intact and nonintact roasts, searing for 15 min at 260°C resulted in reductions in Salmonella populations of ca. 0.3 to 1.3 log CFU/g. For intact (nontenderized) rib eye roasts, cooking to internal temperatures of 37.8 or 48.9°C resulted in additional reductions of ca. 3.4 log CFU/g. For tenderized (nonintact) rib eye roasts, cooking to internal temperatures of 37.8 or 48.9°C resulted in additional reductions of ca. 3.1 or 3.4 log CFU/g, respectively. Pathogen populations remained relatively unchanged for intact roasts cooked to 37.8 or 48.9°C and for nonintact roasts cooked to 48.9°C when held at 60.0°C for up to 8 h. In contrast, pathogen populations increased ca. 2.0 log CFU/g in nonintact rib eye cooked to 37.8°C when held at 60.0°C for 8 h. Thus, cooking at low temperatures and extended holding at relatively low temperatures as evaluated herein may pose a food safety risk to consumers in terms of inadequate lethality and/or subsequent outgrowth of Salmonella, especially if nonintact rib eye is used in the preparation of prime rib, if on occasion appreciable populations of Salmonella are present in or on the meat, and/or if the meat is not cooked adequately throughout. PMID:26613906

  4. Snapping scapular syndrome secondary to rib intramedullary fixation device

    PubMed Central

    Zaidenberg, Ezequiel E.; Rossi, Luciano A.; Bongiovanni, Santiago L.; Tanoira, Ignacio; Maignon, Gaston; Ranalletta, Maximiliano

    2015-01-01

    Background Scapulo-thoracic joint disorders, including bursitis and crepitus, are commonly misdiagnosed problems and can be a source of persistent pain and dysfunction Presentation of the case This article describes an unusual case of a snapping scapula syndrome secondary to a migration through the lateral cortex of a rib splint intramedullary fixation device into the scapulothoracic joint. Discussion Recently, the operative fixation of multiple ribs fractures with intramedullary fixation devices has become popular. Despite the good outcomes with new rib splint designs, concern remains about the potential complications related to potential loss of fracture reduction with migration of the wire resulting in pain or additional injury to the surrounding tissues. Conclusion Surgeons should pay attention to any protrusion of intramedullary rib implants, especially in the evaluation of routine X-rays following surgical treatment. We should be aware of the possibility of this rare cause of snapping scapula syndrome to avoid delayed diagnosis and consider removing the implant will resolve the pain. PMID:26629853

  5. Unveiling the gating mechanism of ECF Transporter RibU

    NASA Astrophysics Data System (ADS)

    Song, Jianing; Ji, Changge; Zhang, John Z. H.

    2013-12-01

    Energy-coupling factor (ECF) transporters are responsible for uptake of micronutrients in prokaryotes. The recently reported crystal structure of an ECF transporter RibU provided a foundation for understanding the structure and transport mechanism of ECF transporters. In the present study, molecular dynamics (MD) was carried out to study the conformational changes of the S component RibU upon binding by riboflavin. Our result and analysis revealed a critically important gating mechanism, in which part of loop5 (L5') (eleven residues, missing in the crystal structure) between TM5 and TM6 is dynamically flexible and serves as a gate. Specifically, the L5' opens a large cavity accessible to riboflavin from the extracellular space in Apo-RibU and closes the cavity upon riboflavin binding through hydrophobic packing with riboflavin. Thus, L5'is proposed to be the gate for riboflavin binding. In addition, steered molecular dynamics (SMD) simulation is employed to investigate the translocation dynamics of RibU during riboflavin transport. The simulation result does not show evidence that the S component alone can carry out the transport function. Since loop regions are very flexible and therefore could not be resolved by crystallography, their dynamics are hard to predict based on crystal structure alone.

  6. Rib fracture in a horse during an endurance race.

    PubMed

    Trigo, Pablo; Muñoz, Ana; Castejón, Francisco; Riber, Cristina; Hassel, Diana M

    2011-11-01

    We describe a fatal case, in which a horse suffered a fall and as a consequence, rib fractures. Diagnosis was made postmortem and the horse died without showing clear signs of respiratory dysfunction. The retrospective reports of injuries can be important to reduce these traumatic events and to avoid fatalities. PMID:22547844

  7. Comparison of Computed Tomography and Chest Radiography in the Detection of Rib Fractures in Abused Infants

    ERIC Educational Resources Information Center

    Wootton-Gorges, Sandra L.; Stein-Wexler, Rebecca; Walton, John W.; Rosas, Angela J.; Coulter, Kevin P.; Rogers, Kristen K.

    2008-01-01

    Purpose: Chest radiographs (CXR) are the standard method for evaluating rib fractures in abused infants. Computed tomography (CT) is a sensitive method to detect rib fractures. The purpose of this study was to compare CT and CXR in the evaluation of rib fractures in abused infants. Methods: This retrospective study included all 12 abused infants…

  8. Polarized single-mode condition for SOI rib waveguide with large cross section

    NASA Astrophysics Data System (ADS)

    Yuan, Dengpeng; Dong, Ying; Liu, Yujin; Li, Tianjian; Zhang, Xudong; Tan, Yushan

    2015-08-01

    In this paper the single mode condition of silicon-on-insulator (SOI) rib waveguide with large cross section is investigated based on the effective index method (EIM) by using numerical computation and analytical derivation with the consideration of the polarization effects. A polarized single-mode condition for SOI rib waveguide with large cross section is presented, the results from analytical derivation are highly concordant with that from numerical computation. For the vertical single-mode condition, the deviations between HE and EH modes correlate oppositely with the total rib height of rib waveguide, and the critical rib height ratio gradually approaches but never equals to 0.5 with the increase of the total rib height. There, HE mode and EH mode are commonly known as quasi-transverse-electric (TE) mode and quasi-transverse-magnetic (TM) mode respectively. The deviation of the critical rib width between HE and EH modes for the lateral single-mode condition is relatively small, which is a function of the rib height ratio but irrelevant to the total rib height for the specified index profile. The fact that the total rib height, index profile, and polarization of modes have effects on the single-mode condition of SOI rib waveguide with large cross section was demonstrated in this work, which was not discussed in the previous works. The results in this work can give guidance to design, simulation and fabrication of SOI rib waveguide with large cross section in practical applications.

  9. Shanidar 3 Neandertal rib puncture wound and paleolithic weaponry.

    PubMed

    Churchill, Steven E; Franciscus, Robert G; McKean-Peraza, Hilary A; Daniel, Julie A; Warren, Brittany R

    2009-08-01

    Since its discovery and initial description in the 1960s, the penetrating lesion to the left ninth rib of the Shanidar 3 Neandertal has been a focus for discussion about interpersonal violence and weapon technology in the Middle Paleolithic. Recent experimental studies using lithic points on animal targets suggest that aspects of weapon system dynamics can be inferred from the form of the bony lesions they produce. Thus, to better understand the circumstances surrounding the traumatic injury suffered by Shanidar 3, we conducted controlled stabbing experiments with replicas of Mousterian and Levallois points directed against the thoraces of pig carcasses. Stabs were conducted under both high and low kinetic energy conditions, in an effort to replicate the usual impact forces associated with thrusting spear vs. long-range projectile weapon systems, respectively. Analysis of the lesions produced in the pig ribs, along with examination of goat ribs subjected primarily to high kinetic energy stabs from an independent experiment, revealed consistent differences in damage patterns between the two conditions. In the case of Shanidar 3, the lack of major involvement of more than one rib, the lack of fracturing of the affected and adjacent ribs, and the lack of bony defects associated with the lesion (such as wastage, hinging, and radiating fracture lines) suggests that the weapon that wounded him was carrying relatively low kinetic energy. While accidental injury or attack with a thrusting spear or knife cannot absolutely be ruled out, the position, angulation, and morphology of the lesion is most consistent with injury by a low-mass, low-kinetic energy projectile weapon. Given the potential temporal overlap of Shanidar 3 with early modern humans in western Asia, and the possibility that the latter were armed with projectile weapon systems, this case carries more than simple paleoforensic interest. PMID:19615713

  10. Fixation of a human rib by an intramedullary telescoping splint anchored by bone cement.

    PubMed

    Liovic, Petar; Šutalo, Ilija D; Marasco, Silvana F

    2016-09-01

    A novel concept for rib fixation is presented that involves the use of a bioresorbable polymer intramedullary telescoping splint. Bone cement is used to anchor each end of the splint inside the medullary canal on each side of the fracture site. In this manner, rib fixation is achieved without fixation device protrusion from the rib, making the splint completely intramedullary. Finite element analysis is used to demonstrate that such a splint/cement composite can preserve rib fixation subjected to cough-intensity force loadings. Computational fluid dynamics and porcine rib experiments were used to study the anchor formation process required to complete the fixation. PMID:26733094

  11. Unsteady flow patterns in the vicinity of heated wall-mounted transverse ribs.

    PubMed

    Polidori, Guillaume; Padet, Jacques

    2002-10-01

    This paper deals with experimental modeling of the unsteady junction flow features in the vicinity of an isoflux heated wall with mounted insulated rectangular ribs representing three distinctive ribbed test geometries. Both flow visualizations and surface temperature distributions show that the blockage effect upstream of the ribs, as well as the presence of complex eddy structures inside the open cavities, significantly affect the heat transfer process. All the configurations indicate degraded heat transfer performance in the area close to the ribs and an enhancement just downstream from the last rib. PMID:12496017

  12. Topological and sizing optimization of reinforced ribs for a machining centre

    NASA Astrophysics Data System (ADS)

    Chen, T. Y.; Wang, C. B.

    2008-01-01

    The topology optimization technique is applied to improve rib designs of a machining centre. The ribs of the original design are eliminated and new ribs are generated by topology optimization in the same 3D design space containing the original ribs. Two-dimensional plate elements are used to replace the optimum rib topologies formed by 3D rectangular elements. After topology optimization, sizing optimization is used to determine the optimum thicknesses of the ribs. When forming the optimum design problem, multiple configurations of the structure are considered simultaneously. The objective is to minimize rib weight. Static constraints confine displacements of the cutting tool and the workpiece due to cutting forces and the heat generated by spindle bearings. The dynamic constraint requires the fundamental natural frequency of the structure to be greater than a given value in order to reduce dynamic deflection. Compared with the original design, the improvement resulting from this approach is significant.

  13. Rib shape recognition in lung x-ray images for intelligent assistance

    NASA Astrophysics Data System (ADS)

    Sakaida, Hideyuki; Oosawa, Akira; Shimura, Kazuo

    2006-03-01

    The purpose of this research is to develop a method for recognizing shapes of ribs in chest x-rays, which can be utilized as intelligent assistance to diagnosis to decrease false positives (FPs) due to ribs in chest CAD and automatically generate a schema in report. Shapes of ribs are manually extracted from several CR images to create a rib shape model using PDM, in which shapes of anterior/posterior ribs are represented as sets of coordinates and an arbitrary shape of a rib is expressed only with principle components that have a high contribution ratio to shape variation. Shapes of ribs in a chest X-ray image are identified as follows: (a) Identify the lung field. (b) Find an allowable range of weights of principle components in the shape model within which the model aligns to an edge of the lung field (a). (c) Create several shape model images by applying different weights of principle components. (d) Apply a six-direction Gabor filter to the X-ray image and each one of the shape model images to create an image containing only rib elements. (e) From images created in (d), search for a shape model image that shows the highest correlation coefficient with the X-ray image.We applied the rib shape model to 100 test images while changing weights of principle components. We were able to identify positions of ribs and anatomical rib numbers with an average margin of error being no more than two fifths of a rib and a half of a rib in case of anterior ribs.

  14. The totem pole rib graft reconstruction of the nose.

    PubMed

    Gerow, F J; Stal, S; Spira, M

    1983-10-01

    The totem pole rib bone graft for nasal reconstruction is presented as an effective way to prepare the donor bone for the correction of saddle-nose deformity. The article's title emanates from the fact that when the sculpturing of the rib is completed it has the appearance of a totem pole before the separate parts are disarticulated for insertion into the nose. The use of this technique permits an accurate, detailed sculpturing of the component parts of the subsequent reconstruction, permitting correction of each feature of the saddle-nose deformity. If these bony segments were dissected or sculptured separately, the smallness of each part would make it very difficult to carve the precise definition needed for a reconstruction that would give structural support and at the same time afford an aesthetically pleasing result. The rationale of the technique and representative cases are presented. PMID:6638830

  15. Rhinoplasty and rib grafts: evolving a flexible operative technique.

    PubMed

    Daniel, R K

    1994-10-01

    A flexible operative technique for utilizing rib grafts in difficult rhinoplasty and nasal reconstruction cases requiring support is presented. An osseocartilaginous rib segment is used for dorsal contour or support, while a rigid cartilaginous strut provides for both tip projection and columellar contour. The bone is contoured extensively, while the cartilage is altered minimally. An open approach is employed. A bony fixation platform is established by radix reduction followed by bony fixation with ultramicroscrews. Distally, the grafts are united when nasal lengthening or total support is required; otherwise, the grafts are juxtaposed to allow lateral movement. The operative technique and technical difficulties are described in detail based on experience in 14 patients. PMID:7938282

  16. Reducing the morbidity involved in harvesting autogenous rib cartilage.

    PubMed

    Siegert, Ralf; Magritz, Ralph

    2009-08-01

    Although the use of autogenous cartilage is the gold standard in auricular reconstruction, its main disadvantage is the morbidity due to harvesting the cartilage. This includes postoperative pain, visible scar, and possibly asymmetry and reduced stability of the thorax. To reduce all of these drawbacks, we describe some modifications that reduce pain to a low tolerable level, hide the scar invisibly in the submammary fold in females, and induce regeneration as well reestablish stability of the rib defect. PMID:19809948

  17. Autologous Rib Grafts in the Management of the Crooked Nose.

    PubMed

    Porter, Paul; Kriet, J David; Humphrey, Clinton D

    2015-06-01

    Rhinoplasty is arguably one of the most challenging procedures a facial plastic surgeon performs. Numerous techniques have been developed since the inception of rhinoplasty to aid in correction of aesthetic and functional issues. Congenital, iatrogenic, and traumatic etiologies can all lead to a crooked nose. Autologous rib or costal cartilage grafting is a powerful tool that can aid the surgeon in successful correction of the crooked nose. PMID:26126219

  18. DiGeorge syndrome with vertebral and rib dysplasia

    SciTech Connect

    Puno-Cocuzza, C.; David, K.; Kogekar, N.

    1994-09-01

    DiGeorge syndrome results from defect in the development of the third and fourth pharyngeal pouches, and is characterized by conotruncal heart defects, aplasia or hypoplasia of thymus and parathyroid glands resulting in immune deficiency and hypocalcemia. Other associated abnormalities include renal, thyroid and diaphragmatic defects, oral clefting, etc. Etiologically, it is heterogeneous, with a microdeletion of 22q11 present in over 80% of cases. Our patient was born following a pregnancy complicated by insulin dependent gestational diabetes. There was truncus arteriosus type 2, absense of thymic shadow on CXR with severe deficiency of T cell function, and persistent hypocalcemia with low parathormone. Right kidney was absent. Dysplastic ribs including fused and bifid ribs were noted. Hypoplastic vertebrae and hemivertebrae were present through thoracic and lumbar regions. Chromosome analysis was normal, and metaphase FISH analysis with probe N25 representing locus D22S75 did not show any deletion of 22q11.2. The skeletal findings similar to these have not been previously reported in association with DiGeorge syndrome to our knowledge. Vertebral and rib abnormalities are known to occur with pregestational maternal diabetes. Maternal diabetes has also been suggested to be a possible etiology in a very small proportion of DiGeorge syndrome cases. It is possible that these findings occured together on account of gestational maternal diabetes in our case.

  19. The effect of spacer ribs on Ledinegg type flow instabilities

    SciTech Connect

    Coutts, D.A.

    1993-09-09

    An experimental program has been completed which evaluated the effect of a flow obstruction in a heated channel on the onset of flow instability (OBI). The test channel was rectangular (80 {times} 3 mm), heated on one surface, and equipped with view ports. Tests were conducted in a flow controlled mode at heat fluxes of 370 kW/M{sup 2}, and 610 kW/m{sup 2}. Direct comparisons were made between the demand curve minimum for the unobstructed channel and a channel equipped with a 2.07 mm wide rib that was parallel to the flow and in contact with the heated surface. Data at OFI is presented in the nondimensional terms Of Q{sub ratio} (ratio of heat flux applied to heat flux required to achieve saturated liquid conditions at the exit), and the local Stanton number at the channel exit for each channel arrangement. The Q{sub ratio} and Stanton number values for the unobstructed channel and the rib equipped channel are then compared to produce an estimate of the rib effect.

  20. Micromilling of thin ribs with high aspect ratios

    NASA Astrophysics Data System (ADS)

    Li, P.; Zdebski, D.; Langen, H. H.; Hoogstrate, A. M.; Oosterling, J. A. J.; Munnig Schmidt, R. H.; Allen, D. M.

    2010-11-01

    Micro features with high aspect ratios are one of the commonly encountered geometries found in micro products. In the literature, these structures are often used in demonstrator products machined by a micromilling process. In this paper, the challenges in micromilling thin ribs with high aspect ratios have been studied. Due to the scaling effect, micro-ribs have relatively low stiffness but high natural frequency. Therefore, on the one hand, average forces have to be controlled well to avoid structural bending or even damage, while on the other hand, micro features are unlikely to be excited by the dynamic forces. The characteristics of micromilling forces and their relationships to the machining parameters, namely, feed per tooth, depth of cut and width of cut, were studied theoretically by force models. In addition, the effects of different milling strategies (up-/down-milling) and tool paths on the quality of thin features have been investigated using FEM. The results allow measures to be taken to minimize the force effects and support the micro features during machining. The experimental results verify the theoretical studies. Thin ribs about 15 µm wide and with an aspect ratio of more than 50 were machined with good form and surface quality.

  1. Turbulent Flow Inside Pipes with Two-Dimensional Rib Roughness

    Energy Science and Technology Software Center (ESTSC)

    1994-01-24

    A commonly used internal enhancement for single-phase forced-convective turbulent flow applications is tranverse and/or near tranverse ribs. These enhanced surfaces consist of a uniform inside diameter with periodic and discrete disruption of ribs. Enhanced tubes of this type are made by an extrusion process and are used in some condensers and evaporators in refrigeration systems. Tubes of this type fall into an enhancement category called separation and reattachment that has been identified as one ofmore » the most energy efficient. Lacking are prediction methods that are mechanistic based that can be used to calculate the heat-transfer coefficients and friction-factors for tubes with this enhancement type. This program calculates the Nusselt number and friction factor for enhanced tubes with tranverse, rectangular ribs with a spacing exceeding the reattachment length. The input quantities are the enhancement height, spacing, and the width. The Nusselt number and friction factor are calculated for a specific Reynolds number or for a range of Reynolds numbers. Users of the program are heat-exchanger designers, enhanced tubing suppliers, and research organizations or academia who are developing or validating prediction methods. The manufacturers of refrigeration heat exchangers and enhanced tube suppliers are potential users of this software.« less

  2. Non-diffuseness of vibration fields in ribbed plates.

    PubMed

    Brunskog, Jonas; Chung, Hyuck

    2011-03-01

    This paper presents numerical simulations of structural intensity in a rib-reinforced plate, investigating the diffuseness. Many prediction models of building and structural acoustics, such as statistical energy analysis or energy flow methods, assume the vibrational wave fields to be diffuse. However, the diffuseness assumption is not always valid. One such example is a rib-reinforced plate typically found in a lightweight floor with wooden joists. Other examples can be found in aircraft and ship structures. The structural intensity of a ribbed plate is computed at low to mid frequencies using the Fourier sine expansion of the transverse displacement of the plate. Hamilton's principle is used in combination with thin plate theory and Euler beam theory. The model takes into account interactions between components. The Fourier sine modes are re-formulated as plane waves in a radial coordinate system, which can express the structural intensity in terms of the angular component of the modes. In the simulations, ensemble averages and rain-on-the-roof excitations are used. The numerical results show that the structural intensity varies significantly as the angle of propagation changes and cannot be assumed to form a diffuse field. PMID:21428497

  3. Osteochondroma of the Rib: a rare radiological apeareance

    PubMed Central

    Kadu, Vikram V; Saindane, K A; Goghate, Ninad; Goghate, Neha

    2015-01-01

    Introduction: Osteochondromas (exostosis) are the most common neoplasm of bone and arise from the metaphysis of bones. Tumors of the chest wall comprise approximately 2% of all tumors of the body and may be primary or metastatic, benign or malignant. Osteochondroma is a common bone tumor but a rare tumor in the rib. It is often asymptomatic and observed incidentally. The tumors typically begin to grow before puberty and continue until bone maturation is reached. Surgery is required in childhood if these lesions are painful or disfiguring, while those arising in adulthood should always be resected. Case Report: 9 yr old boy presented to OPD with swelling over right chest. Radiograph showed bony outgrowth on the lateral aspect of the 6th rib. The patient was kept under closed observation and was treated conservatively. Three years follow-up didn’t show any increase in the size of the swelling and the patient did not have any complaints. Conclusion: Though various studies have shown that the surgical resection of osteochondroma is necessary to avoid further complications of Haemothorax, pneumothorax or intercostal neuralgia, we concluded that osteochondroma of the ribs can even be conserved if not associated with complications and patient does not need to undergo unnecessary surgery.

  4. 'Traction ribs' on the palaeo-ice stream tracks of the Interior Plains, North America

    NASA Astrophysics Data System (ADS)

    Margold, Martin; Stokes, Chris R.

    2015-04-01

    Spatially distinct pattern of basal shear stress beneath a number of Antarctic and Greenlandic ice streams has recently been discovered by inverse methods using high resolution data of ice velocity, elevation and thickness. Surrounded by regions of near-zero basal shear stress, these areas of high basal shear stress have been termed 'traction ribs' and hold important implications for the force balance of ice streams. The cause of the traction ribs is unknown (i.e. whether they have a topographic expression), but their horizontal dimensions and pattern lie somewhere between typical ribbed (Rogen) moraines and recently described mega-scale ribbed moraines identified on palaeo-ice sheet beds. However, whilst both of these landform types form with their long axis transverse to the ice flow direction, the traction ribs are most commonly oriented oblique to the ice flow at angles of 30-60 degrees. Here, we report new findings from the beds of palaeo-ice streams on the Interior Plains in Alberta and Saskatchewan where landform assemblages, similar to traction ribs, occur at several sites. Individual landforms at the mapped sites have typical lengths (transverse to flow) of 5-10 km, width of ~2 km, and their spacing is ~2-3 km. As such, they appear to represent an intermediate scale of ribbed landform that overlaps with the more extreme (larger) values of classic ribbed moraine and the smaller values of mega-ribs. Unlike mega-ribs and ribbed moraines, we also note that many of the ribbed features we mapped are aligned obliquely to ice flow direction at angles and mimic the arcuate patterns of traction ribs seen under modern ice streams. Profiles across the ridges indicate that they have amplitudes of 10-15 m which is comparable, but slightly lower than the mean value for ribbed moraines. The resemblance of our newly mapped features to the traction ribs of modern ice streams is close not only in the size and shape but also in the overall pattern of the whole landform

  5. Effects of Pin Detached Space on Heat Transfer in a Rib Roughened Channel

    SciTech Connect

    Siw, Sin Chien; Chyu, Minking K.; Alvin, Mary Anne

    2013-03-01

    An experimental study is performed to investigate the heat transfer characteristics and frictional losses in a rib roughened channel combined with detached pin-fins. The overall channel geometry (W = 76.2 mm, E = 25.4 mm) simulates an internal cooling passage of wide aspect ratio (3:1) in a gas turbine airfoil. With a given pin diameter, D = 6.35 mm = [1/4]E, three different pin-fin height-to-diameter ratios, H/D = 4, 3, and 2, were examined. Each of these three cases corresponds to a specific pin array geometry of detachment spacing (C) between the pin-tip and one of the endwalls, i.e., C/D = 0, 1, 2, respectively. The rib height-to-channel height ratio is 0.0625. Two newly proposed cross ribs, namely the broken rib and full rib are evaluated in this effort. The broken ribs are positioned in between two consecutive rows of pin-fins, while the full ribs are fully extended adjacent to the pin-fins. The Reynolds number, based on the hydraulic diameter of the unobstructed cross section and the mean bulk velocity, ranges from 10,000 to 25,000. The experiment employs a hybrid technique based on transient liquid crystal imaging to obtain distributions of the local heat transfer coefficient over all of the participating surfaces, including the endwalls and all pin elements. The presence of ribs enhances local heat transfer coefficient on the endwall substantially by approximately 20% to 50% as compared to the neighboring endwall. In addition, affected by the rib geometry, which is a relatively low profile as compared to the overall height of the channel, the pressure loss seems to be insensitive to the presence of the ribs. However, from the overall heat transfer enhancement standpoint, the baseline cases (without ribs) outperform cases with broken ribs or full ribs.

  6. Serratus anterior-rib composite flap: anatomic studies and clinical application to hand reconstruction.

    PubMed

    Hui, K C; Zhang, F; Lineaweaver, W C; Moon, W; Buncke, G M; Buncke, H J

    1999-02-01

    Because of its relative ease of dissection, increased length of the vascular pedicle, and excellent diameter for anastomosis, the serratus anterior-rib composite flap has been used to reconstruct bony and soft-tissue defects in the face and lower extremities. However, no data are available on optimal rib level or harvest location. The authors report the results of the vascular anatomy of this flap in 6 fresh cadavers and 2 clinical patients using this flap to reconstruct a defect in the hand. Arteriograms were performed through the thoracodorsal artery, and microscopic dissections were done at the rib periosteum. The sixth through the ninth ribs showed consistent filling of their respective intercostal vessels. The rib segments near the anterior axillary line had the most abundant communicating vessels between the serratus and the periosteum. In two patients, the serratus-rib composite free flap provided excellent bone and muscle length for reconstructing the first metacarpal defect. PMID:10029475

  7. Preliminary study of rib articulated model based on dynamic fluoroscopy images

    NASA Astrophysics Data System (ADS)

    Villard, Pierre-Frederic; Escamilla, Pierre; Kerrien, Erwan; Gorges, Sebastien; Trousset, Yves; Berger, Marie-Odile

    2014-03-01

    We present in this paper a preliminary study of rib motion tracking during Interventional Radiology (IR) fluoroscopy guided procedures. It consists in providing a physician with moving rib three-dimensional (3D) models projected in the fluoroscopy plane during a treatment. The strategy is to help to quickly recognize the target and the no-go areas i.e. the tumor and the organs to avoid. The method consists in i) elaborating a kinematic model of each rib from a preoperative computerized tomography (CT) scan, ii) processing the on-line fluoroscopy image and iii) optimizing the parameters of the kinematic law such as the transformed 3D rib projected on the medical image plane fit well with the previously processed image. The results show a visually good rib tracking that has been quantitatively validated by showing a periodic motion as well as a good synchronism between ribs.

  8. Evaluation of intensity based beam-shaping method with Rib-phantom HIFU sonications

    NASA Astrophysics Data System (ADS)

    Tillander, Matti; Köhler, Max; Koskela, Julius; Ylihautala, Mika

    2012-11-01

    The relation between rib bone heating during HIFU therapy and incident intensity on the bone surface was examined using an experimental setup and simulations with ray-tracer. The relation was found to be linear yet the data had large variance. The result was successfully applied to an intensity-based beam-shaping algorithm, which was fast enough for online therapy planning, and used to protect the ribs from overheating during intercostal sonications to a HIFU phantom containing two porcine rib bones.

  9. A study of general instability of box beams with truss-type ribs

    NASA Technical Reports Server (NTRS)

    Lundquist, Eugene E; Schwartz, Edward B

    1942-01-01

    The design of truss-type ribs for box beams is theoretically treated with regard to the function of the ribs in stabilizing the compression flange. The theory is applied to a design problem, and the results of this application are presented and discussed in relation to the general problem of rib design. The results of some tests made as a part of this general study are presented in an appendix.

  10. Analysis of quantitative methods for rib seriation using the Spitalfields documented skeletal collection.

    PubMed

    Owers, Sonya K; Pastor, Robert F

    2005-06-01

    Accurate rib seriation is essential in forensic anthropology and bioarchaeology for determination of minimum numbers of individuals, sequencing trauma patterns to the chest, and identification of central ribs for use in age estimation. We investigate quantitative methods for rib seriation based on three metric variables: superior (anterior) costo-transverse crest height (SCTCH), articular facet of the tubercle-to-angle length (AFTAL), and head-to-articular facet length (HAFL). The sample consists of complete but unseriated sets of ribs from 133 individuals from the documented (known age and sex) and undocumented skeletal collections of Christ Church Spitalfields, London. This research confirms the results of an earlier study (Hoppa and Saunders [1998] J. Forensic. Sci. 43:174-177) and extends it with the application of two new metric traits and further analyses of sex differences. Analyses of variance showed that SCTCH and AFTAL are significantly associated (P < 0.001) with rib number. Tukey tests of pairwise rib comparisons revealed that for two dimensions (SCTCH and AFTAL), the central ribs (3rd-6th) are significantly distinct from each other (P < 0.05). Using simple ranking of either the SCTCH or AFTAL traits, the proportion of correctly identified ribs within +/-1 position was 80%, compared to initial seriation using morphological methods (Dudar [1993] J. Forensic. Sci. 28:788-797; Mann [1993] J. Forensic. Sci. 28:151-155). Significant sex dimorphism was also identified for these two traits. Analysis of the HAFL trait produced somewhat equivocal results, suggesting that this variable is not reliable for rib seriation. The variable SCTCH proves to be the most useful dimension for seriation, and shows that all but the 7th-9th ribs can be distinguished from others in the sequence, with important results for the 4th rib, where ranking allowed identification in 86% of cases, consistent with morphological methods for intact ribs. PMID:15503341

  11. XROMM analysis of rib kinematics during lung ventilation in the green iguana, Iguana iguana.

    PubMed

    Brainerd, Elizabeth L; Moritz, Sabine; Ritter, Dale A

    2016-02-01

    The three-dimensional rotations of ribs during breathing are typically described as bucket-handle rotation about a dorsoventrally oriented axis, pump-handle rotation about a mediolateral axis, and caliper rotation about a rostrocaudal axis. In amniotes with double-headed ribs, rib motion is constrained primarily to one degree-of-freedom (DOF) rotation about an axis connecting the two rib articulations. However, in Squamata, the ribs are single headed and the hemispherical costovertebral joints permit rotations with three DOF. In this study, we used X-ray reconstruction of moving morphology (XROMM ) to quantify rib rotation during deep breathing in four green iguanas. We found that rib rotation was strongly dominated by bucket-handle rotation, thus exhibiting nearly hinge-like motion, despite the potential for more complex motions. The vertebral and sternal segments of each rib did not deform measurably during breathing, but they did move relative to each other at a thin, cartilaginous intracostal joint. While standing still and breathing deeply, four individual iguanas showed variability in their rib postures, with two breathing around a highly inflated posture, and two breathing around a posture with the ribs folded halfway back. Bucket-handle rotations showed clear rostrocaudal gradients, with rotation increasing from the third cervical to the first or second dorsal rib, and then decreasing again caudally, a pattern that is consistent with the intercostal muscles in the rostral intercostal spaces being the primary drivers of inspiration. The constrained, primarily bucket-handle rotations observed here during breathing do not help to explain the evolution of permissive, hemispherical costovertebral joints in squamates from the more constrained, double-headed rib articulations of other amniotes. PMID:26596531

  12. Quantitative analysis of rib movement based on dynamic chest bone images: preliminary results

    NASA Astrophysics Data System (ADS)

    Tanaka, R.; Sanada, S.; Oda, M.; Mitsutaka, M.; Suzuki, K.; Sakuta, K.; Kawashima, H.

    2014-03-01

    Rib movement during respiration is one of the diagnostic criteria in pulmonary impairments. In general, the rib movement is assessed in fluoroscopy. However, the shadows of lung vessels and bronchi overlapping ribs prevent accurate quantitative analysis of rib movement. Recently, an image-processing technique for separating bones from soft tissue in static chest radiographs, called "bone suppression technique", has been developed. Our purpose in this study was to evaluate the usefulness of dynamic bone images created by the bone suppression technique in quantitative analysis of rib movement. Dynamic chest radiographs of 10 patients were obtained using a dynamic flat-panel detector (FPD). Bone suppression technique based on a massive-training artificial neural network (MTANN) was applied to the dynamic chest images to create bone images. Velocity vectors were measured in local areas on the dynamic bone images, which formed a map. The velocity maps obtained with bone and original images for scoliosis and normal cases were compared to assess the advantages of bone images. With dynamic bone images, we were able to quantify and distinguish movements of ribs from those of other lung structures accurately. Limited rib movements of scoliosis patients appeared as reduced rib velocity vectors. Vector maps in all normal cases exhibited left-right symmetric distributions, whereas those in abnormal cases showed nonuniform distributions. In conclusion, dynamic bone images were useful for accurate quantitative analysis of rib movements: Limited rib movements were indicated as a reduction of rib movement and left-right asymmetric distribution on vector maps. Thus, dynamic bone images can be a new diagnostic tool for quantitative analysis of rib movements without additional radiation dose.

  13. Resection of supernumerary intrathoracic rib using robotic-assisted video-assisted thoracoscopic surgery.

    PubMed

    Coyan, Garrett; Daon, Emmanuel

    2016-05-01

    A supernumerary intrathoracic rib is a very rare congenital thoracic abnormality that is typically a benign incidental finding. However, in rare cases, they may cause pain, pneumothorax, and injury to surrounding viscus. We report a case of a supernumerary intrathoracic rib causing increasing chest pain diagnosed by computed tomography using three-dimensional reconstructions. The patient underwent robotic-assisted video-assisted thoracoscopic resection of the intrathoracic rib located in her left thorax. The rib was resected without complication, and the patient was discharged from the telemetry unit on post-operative day two. Upon discharge, there was complete resolution of her preoperative symptoms. PMID:26520667

  14. Rib Fracture Patterns and Radiologic Detection – A Restraint-Based Comparison

    PubMed Central

    Crandall, Jeff; Kent, Richard; Patrie, James; Fertile, Jay; Martin, Peter

    2000-01-01

    This paper presents a study of the rib fracture patterns generated in simulated frontal collisions and the visibility of the rib fractures on plain film radiographs. Using 29 cadaver subjects, rib fractures were identified on oblique, lateral, and anteroposterior chest films by five radiologists independently and were compared with fractures found during a detailed necropsy. Physical, geometric, and experimental factors demonstrated an influence on the ability of a radiologist to identify rib fractures on an x-ray. Specifically, the restraint system configuration, the total number of fractures, the circumferential location of the fracture, the rib number, and the aspect (right or left) affected fracture identification. The results verify that torso belt loading produces rib fractures generally located along the path of the belt whereas superimposed airbag loading results in a more distributed and posterolateral fracture pattern. A higher proportion of rib fractures was identified on x-ray for occupants restrained by only a belt (44% of fractures) than for occupants restrained by both a belt and an airbag (24% of fractures). Overall, less than 40% of the rib fractures were detected upon an initial examination of radiographs. After being provided with the location of all fractures, detection increased to 49%. On average, occult rib fractures resulted in an average underreporting of injury severity of more than one AIS level. PMID:11558086

  15. Cold plate with combined inclined impingement and ribbed channels

    DOEpatents

    Parida, Pritish R.

    2015-12-22

    Heat transfer devices and methods for making the same that include a first enclosure having at least one inlet port; a second enclosure having a bottom plate and one or more dividing walls to establish channels, at least one internal surface of each channel having rib structures to create turbulence in a fluid flow; and a jet plate connecting the first enclosure and the second enclosure having impinging jets that convey fluid from the first enclosure to the channels, said impinging jets being set at an angular deviation from normal to cause local acceleration of fluid and to increase a local heat transfer rate.

  16. Flexible polymeric rib waveguide with self-align couplers system.

    PubMed

    Huang, Cheng-Sheng; Wang, Wei-Chih

    2008-01-01

    The authors report a polymeric based rib waveguide with U shape self-align fiber couplers system using a simple micromolding process with SU8 as a molding material and polydimethysiloxane as a waveguide material. The material is used for its good optical transparency, low surface tension, biocompatibility, and durability. Furthermore, the material is highly formable. This unique fabrication molding technique provides a means of keeping the material and manufacturing costs to a minimum. The self-align fiber couplers system also proves a fast and simple means of light coupling. The flexible nature of the waveguide material makes this process ideal for a potential wearable optical sensor. PMID:22171151

  17. Rib pillar extraction - An alternative to longwalling and shortwalling

    SciTech Connect

    Habenicht, H.; Urschitz, E.

    1987-06-01

    Three mining methods for full extraction in flat coal seams - i.e., longwall (LW), shortwall (SW), and rib pillar extraction (RPE) - are compared with each other in view of the introduction of a mechanized, self-advancing roof support. Features are shown according to which RPE appears most attractive under certain conditions. In this presentation, the mining methods are outlined and discussed. The new support (Alpine Breaker Line Support, ABLS) is described, and its employment is explained. A trial operation in RPE using the ABLS has been conducted successfully in a South African coal mine. The results and improvements are stated.

  18. Epithelioid hemangioendothelioma originating from the chest wall with rib metastases.

    PubMed

    Shimamura, Junichi; Kiyoshima, Moriyuki; Suzuki, Hisashi; Kitahara, Miyuki; Asato, Yuji; Iijima, Tatsuo; Amemiya, Ryuta

    2015-11-01

    An asymptomatic 39-year-old woman was referred to us for an abnormal nodular opacity detected on the chest X-ray. Histopathological and further examinations revealed findings consistent with epithelioid hemangioendothelioma (EHE) originating from the chest wall with metastases to the ribs. Complete excision was performed; however, adjuvant chemotherapy was not administered because of the patient's mental disorder. There are very few reports of EHE arising from the chest wall; therefore, we present this case report with the clinicopathological features of EHE and discuss the therapeutic aspects. PMID:24399489

  19. Supercontinuum generation in dispersion-managed tapered-rib waveguide.

    PubMed

    Hu, Hongyu; Li, Wenbo; Dutta, Niloy K

    2013-10-20

    We have designed a tapered-rib waveguide and numerically studied the generation of supercontinuum using such waveguides. The Air-SF57 glass-SiO(2) waveguide is 3 cm long, with a varying etched depth to manage the total dispersion. Numerical simulations are conducted for input pulses at a wavelength of 1.55 μm with a width of 150 fs and peak power of 5 kW. The proposed waveguide geometry greatly broadens the output spectrum, extending from ∼1 to ∼6  μm, caused by the continuous modification of the phase-matching condition for the generated waves. PMID:24216588

  20. Rib Cartilage Assessment Relative to the Healthy Ear in Young Children with Microtia Guiding Operative Timing

    PubMed Central

    Kang, Shen-Song; Guo, Ying; Zhang, Dong-Yi; Jiang, Du-Yin

    2015-01-01

    Background: The optimal age at which to initiate for auricular reconstruction is controversial. Rib cartilage growth is closely related to age and determines the feasibility and outcomes of auricular reconstruction. We developed a method to guide the timing of auricular reconstruction in children with microtia ranging in age from 5 to 10 years. Methods: Rib cartilage and the healthy ear were assessed using low-dose multi-slice computed tomography. The lengths of the eighth rib cartilage and the helix of the healthy ear (from the helical crus to the joint of the helix and the earlobe) were measured. Surgery was performed when the two lengths were approximately equal. Results: The preoperative eighth rib measurements significantly correlated with the intraoperative measurements (P < 0.05). From 5 to 10 years of age, eighth rib growth was not linear. In 76 (62.8%) of 121 patients, the eighth rib length was approximately equal to the helix length in the healthy ear; satisfactory outcomes were achieved in these patients. In 18 (14.9%) patients, the eighth rib was slightly shorter than the helix, helix fabrication was accomplished by adjusting the length of the helical crus of stent, and satisfactory outcomes were also achieved. Acceptable outcomes were achieved in 17 (14.0%) patients in whom helix fabrication was accomplished by cartilage splicing. In 9 (7.4%) patients with insufficient rib cartilage length, the operation was delayed. In one (0.8%) patient with insufficient rib cartilage length, which left no cartilage for helix splicing, the result was unsatisfactory. Conclusions: Eighth rib cartilage growth is variable. Rib cartilage assessment relative to the healthy ear can guide auricular reconstruction and personalize treatment in young patients with microtia. PMID:26265615

  1. Rib osteoblastic osteosarcoma in an African hedgehog (Atelerix albiventris).

    PubMed

    Benoit-Biancamano, Marie-Odile; D'Anjou, Marc-André; Girard, Christiane; Langlois, Isabelle

    2006-07-01

    A 3-year-old African hedgehog (Atelerix albiventris) was presented to the Exotic Animal Clinic of the University of Montreal for evaluation of a mass growing on the right thoracic wall. The diagnostic workup, which included helical computed tomography, confirmed the presence of a large mass, originating from the right 7th rib, infiltrating the thoracic wall and cavity. The animal was euthanized due to the poor prognosis. At necropsy, a well-demarcated mass penetrated the thoracic wall and incorporated the 6th to 8th ribs. Cut sections of the tumor were white, glistening, firm, and gritty. Microscopically, it was composed of polyhedral to elongated cells with interspersed trabeculae of osteoid and large areas of coagulative necrosis. On the basis of histopathologic findings, a diagnosis of osteoblastic osteosarcoma was made. To the authors' knowledge, this is the first report of an osteoblastic osteosarcoma on the thoracic wall of an African hedgehog, as well as the first report of the use of helical computed tomography in that species. PMID:16921888

  2. Prediction of Moisture Distribution in Closed Ribbed Panel for Roof

    NASA Astrophysics Data System (ADS)

    Kukule, A.; Rocens, K.

    2015-11-01

    Nowadays one of the possibilities to improve energy efficiency is the use of building elements with low air permeability, for example, sandwich panels with steel sheeting. However, these panels have one important disadvantage - a relatively small load-bearing capacity. This can be prevented by reinforcing the panel with antiseptized birch plywood ribs. For wood-based materials prediction of hygrothermal performance is important to avoid rot. Currently the methodology of ISO 13788:2012 is widely used assuming that moisture flux passes through the building envelope of any material. This assumption is not completely accurate with regard to a closed structure where no penetration of ambient humidity is possible. Therefore, in order to predict the distribution of moisture in such structure with the surfaces exposed to different temperatures and to assess the hazards of rot for plywood ribs, a methodology for closed building envelope is presented. To provide insight into expected results according to both methodologies, estimation for individual case with constant environmental conditions is given. According to the methodology for the closed building envelope no free water will occur. Therefore, it is believable that also no rot will be observed. This is contrary to the assessment according to the methodology of ISO 13788:2012, which predicts condensation.

  3. An unusual cause of rib fracture following a road traffic accident.

    PubMed Central

    Daniels, R J; Fulcher, R A

    1997-01-01

    A case is presented which is thought to be the first described example of rib fracture occurring as a result of airbag inflation. It would appear that the propellant cartridge came loose during deployment to form a missile, striking the patient on his chest and fracturing a rib. Images Figure 1 Figure 2 Figure 3 PMID:9132187

  4. 30 CFR 75.202 - Protection from falls of roof, face and ribs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Protection from falls of roof, face and ribs. 75.202 Section 75.202 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Roof Support § 75.202 Protection from falls of roof, face and ribs....

  5. Does Cardiopulmonary Resuscitation Cause Rib Fractures in Children? A Systematic Review

    ERIC Educational Resources Information Center

    Maguire, Sabine; Mann, Mala; John, Nia; Ellaway, Bev; Sibert, Jo R.; Kemp, Alison M.

    2006-01-01

    Background: There is a diagnostic dilemma when a child presents with rib fractures after cardiopulmonary resuscitation (CPR) where child abuse is suspected as the cause of collapse. We have performed a systematic review to establish the evidence base for the following questions: (i) Does cardiopulmonary resuscitation cause rib fractures in…

  6. Alterations of diaphragm and rib cage morphometry in severe COPD patients by CT analysis.

    PubMed

    Salito, C; Luoni, E; Aliverti, A

    2015-08-01

    Although it is known that in patients with COPD acute hyperinflation determines shortening of the inspiratory muscles, its effects on both diaphragm and rib cage morphology are still to be investigated. In this preliminary study the relationships between hyperinflation, emphysema, diaphragm and rib cage geometry were studied in 5 severe COPD patients and 5 healthy subjects. An automatic software was developed to obtain the 3-D reconstruction of diaphragm and rib cage from CT scans taken at total lung capacity (TLC) and residual volume (RV). Dome surface area (Ado), radius of curvature, length (Ld) and position (referred to xiphoid level) of the diaphragm and antero-posterior (A-P) and transverse (T) diameters of rib cage were calculated at both volumes. Ado and Ld were similar in COPD and controls when compared at similar absolute lung volumes. Radius of curvature was significantly higher in COPD than in controls only at TLC. In COPD, the range of diaphragm position was invariantly below the xiphoid level, while in controls the top of diaphragm dome was always above it. Rib cage diameters were not different at TLC. A-P diameter was greater in COPD than in controls at RV, while T diameters were similar. In conclusion, in severe COPD diaphragm and rib cage geometry is altered at RV. The lower position of diaphragm is associated to smaller A-P but not transversal rib cage diameters, such that rib cage adopts a more circular shape. PMID:26737755

  7. 30 CFR 75.202 - Protection from falls of roof, face and ribs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    .... 75.202 Section 75.202 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Roof Support § 75.202 Protection from falls of roof, face and ribs. (a) The roof, face and ribs of areas where persons work...

  8. Stresses in single-spar wing constructions with incompletely built-up ribs

    NASA Technical Reports Server (NTRS)

    Reinitzhuber, F

    1940-01-01

    It is shown that the force distribution resulting from incomplete ribs in single spar wing structures may be determined with the aid of the shear field method by a statistically indeterminate computation. A numerical computation is given of the force distribution of a wing structure whose two neighboring incomplete ribs with web missing in half the section are torsionally loaded.

  9. Modal density and modal distribution of bending wave vibration fields in ribbed plates.

    PubMed

    Dickow, Kristoffer Ahrens; Brunskog, Jonas; Ohlrich, Mogens

    2013-10-01

    Plates reinforced by ribs or joists are common elements in lightweight building structures, as well as in other engineering structures such as vehicles, ships, and aircraft. These structures, however, are often not well suited for simple structural acoustic prediction models such as statistical energy analysis. One reason is that the modal density is not uniformly distributed due to the spatial periodicity introduced by the ribs. This phenomenon is investigated in the present paper, using a modal model of a ribbed plate. The modal model uses the Fourier sine modes, and the coupling between the plate and ribs is incorporated using Hamilton's principle. This model is then used to investigate the modal density of the considered spatially periodic structure, and a grouping of the modes in different dominating directions is proposed. Suggestions are also given regarding how to proceed towards a simplified prediction model for ribbed plates. PMID:24116410

  10. An experimental investigation of heat transfer characteristics for steam cooling in a rectangular channel with parallel ribs

    NASA Astrophysics Data System (ADS)

    Ma, Chao; Chen, Xiaoling; Wang, Jianfei; Zang, Shusheng; Ji, Yongbin

    2014-10-01

    An experimental study of heat transfer characteristics in superheated steam cooled rectangular channels with parallel ribs was conducted. The distribution of the heat transfer coefficient on the rib-roughed channel was measured by IR camera. The blockage ratio (e/Dh) of the tested channel is 0.078 and the aspect ratio (W/H) is fixed at 3.0. Influences of the rib pitch-to-height ratio (P/e) and the rib angle on heat transfer for steam cooling were investigated. In this paper, the Reynolds number (Re) for steam ranges from 3070 to 14800, the rib pitch-to-height ratios were 8, 10 and 12, and rib angles were 90°, 75°, 60°, and 45°. Based on results above, we have concluded that: In case of channels with 90° tranverse ribs, for larger rib pitch models (the rib pitch-to-height ratio=10 and 12), areas with low heat transfer coefficient in front of rib is larger and its minimum is lower, while the position of the region with high heat transfer coefficient nearly remains the same, but its maximun of heat transfer coefficient becomes higher. In case of channels with inclined ribs, heat transfer coefficients on the surface decrease along the direction of each rib and show an apparent nonuniformity, consequently the regions with low Nusselt number values closely following each rib expand along the aforementioned direction and that of relative high Nusselt number values vary inversely. For a square channel with 90° ribs at Re=14800, wider spacing rib configurations (the rib pitch-to-height ratio=10 and 12) give an area-averaged heat transfer on the rib-roughened surface about 8.4% and 11.4% more than P/e=8 model, respectively; for inclined parallel ribs with different rib angles at Re= 14800, the area-averaged heat transfer coefficients of 75°, 60° and 45° ribbed surfaces increase by 20.1%, 42.0% and 44.4% in comparison with 90° rib angle model. 45° angle rib-roughened channel leads to a maximal augmentation of the area-averaged heat transfer coefficient in all

  11. Focusing of high-intensity ultrasound through the rib cage using a therapeutic random phased array.

    PubMed

    Bobkova, Svetlana; Gavrilov, Leonid; Khokhlova, Vera; Shaw, Adam; Hand, Jeffrey

    2010-06-01

    A method for focusing high-intensity ultrasound (HIFU) through a rib cage that aims to minimize heating of the ribs while maintaining high intensities at the focus (or foci) was proposed and tested theoretically and experimentally. Two approaches, one based on geometric acoustics and the other accounting for diffraction effects associated with propagation through the rib cage, were investigated theoretically for idealized source conditions. It is shown that for an idealized radiator, the diffraction approach provides a 23% gain in peak intensity and results in significantly less power losses on the ribs (1% vs. 7.5% of the irradiated power) compared with the geometric one. A 2-D 1-MHz phased array with 254 randomly distributed elements, tissue-mimicking phantoms and samples of porcine rib cages are used in experiments; the geometric approach is used to configure how the array is driven. Intensity distributions are measured in the plane of the ribs and in the focal plane using an infrared camera. Theoretical and experimental results show that it is possible to provide adequate focusing through the ribs without overheating them for a single focus and several foci, including steering at +/- 10-15 mm off and +/- 20 mm along the array axis. Focus splitting caused by the periodic spatial structure of ribs is demonstrated both in simulations and experiments; the parameters of splitting are quantified. The ability to produce thermal lesions with a split focal pattern in ex vivo porcine tissue placed beyond the rib phantom is also demonstrated. The results suggest that the method is potentially useful for clinical applications of HIFU, for which the rib cage lies between the transducer(s) and the targeted tissue. PMID:20510186

  12. Traumatic Vertebral Fractures and Concomitant Fractures of the Rib in Southwest China, 2001 to 2010

    PubMed Central

    Wang, Hongwei; Zhou, Yue; Ou, Lan; Li, Changqing; Liu, Jun; Xiang, Liangbi

    2015-01-01

    Abstract To our knowledge, the clinical characteristics of traumatic vertebral fractures and concomitant fractures of the rib (TVF-RF) have not been described in previous studies. To investigate the clinical characteristics of patients managed for TVF-RF. A retrospective study of 3142 patients who presented with traumatic vertebral fractures was performed. Two hundred twenty-six patients (7.2%) suffered from TVF-RF. Incidence rate ratios were then calculated with respect to the level of injury to the spine, the ASIA classification of neurological deficits and age. There were 171 male (75.7%) and 55 female (24.3%) patients with a mean age of 43.8 years. The most common mechanisms were falls from high heights in 81 cases and road traffic crashes in 67 cases. Right-sided rib injury occurred in 106 cases, left-sided injury occurred in 76 cases, and bilateral injury occurred in 44 cases. The most frequent location of the rib fractures was from the fourth rib to the ninth rib (70.3%, 510/725). Initial pulmonary complications (IPC) after trauma occurred in 116 cases (51.3%). The mortality rate for the entire group was 1.3% (3/226). The patients with thoracic vertebral fractures and neurological deficits had a higher frequency of multiple rib fractures and IPC than the other patients (P < 0.05). With the increased number of rib fractures, the frequency of IPC and mean intensive care unit (ICU) length of stay also increased. The rates of complications for patients with rib fractures were significantly different from those without rib fractures. We should pay much attention to the patients who presented with thoracic vertebral fractures and neurological deficits for minimizing further complications and mortality in such patients who had a higher frequency of multiple rib fractures and IPC than the other patients. PMID:26554809

  13. Focusing of high intensity ultrasound through the rib cage using a therapeutic random phased array

    PubMed Central

    Bobkova, Svetlana; Gavrilov, Leonid; Khokhlova, Vera; Shaw, Adam; Hand, Jeffrey; #, ||

    2010-01-01

    A method for focusing high intensity ultrasound through a rib cage that aims to minimize heating of the ribs whilst maintaining high intensities at the focus (or foci) is proposed and tested theoretically and experimentally. Two approaches, one based on geometric acoustics and the other accounting for diffraction effects associated with propagation through the rib cage, are investigated theoretically for idealized source conditions. It is shown that for an idealized radiator the diffraction approach provides a 23% gain in peak intensity and results in significantly less power losses on the ribs (1% versus 7.5% of the irradiated power) compared with the geometric one. A 2D 1-MHz phased array with 254 randomly distributed elements, tissue mimicking phantoms, and samples of porcine rib cages are used in experiments; the geometric approach is used to configure how the array is driven. Intensity distributions are measured in the plane of the ribs and in the focal plane using an infra-red camera. Theoretical and experimental results show that it is possible to provide adequate focusing through the ribs without overheating them for a single focus and several foci, including steering at ± 10–15 mm off and ± 20 mm along the array axis. Focus splitting due to the periodic spatial structure of ribs is demonstrated both in simulations and experiments; the parameters of splitting are quantified. The ability to produce thermal lesions with a split focal pattern in ex vivo porcine tissue placed beyond the rib phantom is also demonstrated. The results suggest that the method is potentially useful for clinical applications of HIFU for which the rib cage lies between the transducer(s) and the targeted tissue. PMID:20510186

  14. Interactive Simulation of Diaphragm Motion Through Muscle and Rib Kinematics

    NASA Astrophysics Data System (ADS)

    Villard, Pierre-Frédéric; Bourne, Wesley; Bello, Fernando

    Modeling of diaphragm behaviour is of relevance to a number of clinical procedures such as lung cancer radiotherapy and liver access interventions. The heterogeneity in tissue composition of the diaphragm, as well as the various physiological phenomena influencing its behaviour, requires a complex model in order to accurately capture its motion. In this chapter we present a novel methodology based on a heterogenous model composed of mass-spring and tensegrity elements. The physiological boundary conditions have been carefully taken into account and applied to our model. Thus, it incorporates the influence of the rib kinematics, the muscle natural contraction/relaxation and the motion of the sternum. Initial validation results show that the behaviour of the model closely follows that of a real diaphragm.

  15. Structural efficiency study of composite wing rib structures

    NASA Technical Reports Server (NTRS)

    Swanson, Gary D.; Gurdal, Zafer; Starnes, James H., Jr.

    1988-01-01

    A series of short stiffened panel designs which may be applied to a preliminary design assessment of an aircraft wing rib is presented. The computer program PASCO is used as the primary design and analysis tool to assess the structural efficiency and geometry of a tailored corrugated panel, a corrugated panel with a continuous laminate, a hat stiffened panel, a blade stiffened panel, and an unstiffened flat plate. To correct some of the shortcomings in the PASCO analysis when shear is present, a two step iterative process using the computer program VICON is used. The loadings considered include combinations of axial compression, shear, and lateral pressure. The loading ranges considered are broad enough such that the designs presented may be applied to other stiffened panel applications. An assessment is made of laminate variations, increased spacing, and nonoptimum geometric variations, including a beaded panel, on the design of the panels.

  16. Development of new Hopkinson's device dedicated to rib's bone characterisation

    NASA Astrophysics Data System (ADS)

    Mayeur, O.; Haugou, G.; Chaâri, F.; Delille, R.; Drazetic, P.; Markiewicz, E.

    2012-08-01

    This study presents an original approach for the design of adapted Hopkinson device dedicated to the characterisation of human ribs' cortical bone. The quasi-static study carried out on flat samples coming from this anatomical part highlighted the importance of the critical effect of sample shape and location on the accuracy of identify mechanical behaviour. The access to higher rates of strains, Hopkinson bars technique are classically required whatever compression or tension loadings. Classical designs of measurement bars are not suitable for this purpose due to the complexity of specimen's geometry (thickness variation). In this context, a new design of SHTB is studied here on the basis on a Finite Element approach of the set measurement bars/biological coupon. Finite Element simulations have been conducted using Abaqus explicit code by varying the design configuration. The comparison on input and output elastic waves suggests a set of small diameter bars in polyamide 66 for a better signal measurement.

  17. Local heat transfer distribution in a square channel with 90 continuous, 90 saw tooth profiled and 60 broken ribs

    SciTech Connect

    Gupta, Abhishek; SriHarsha, V.; Prabhu, S.V.; Vedula, R.P.

    2008-02-15

    Internal channel cooling is employed in advanced gas turbines blade to allow high inlet temperatures so as to achieve high thrust/weight ratios and low specific fuel consumption. The objective of the present study is to measure the local heat transfer distributions in a double wall ribbed square channel with 90 continuous, 90 saw tooth profiled and 60 V-broken ribs. Comparison is made between the 90 continuous ribs (P/e = 7 and 10 for a e/D = 0.15) and 90 saw tooth profiled rib configurations (P/e = 7 for an e/D = 0.15) for the same rib height to the hydraulic diameter ratio (e/D). The effect of pitch to rib height ratio (P/e = 7.5,10 and 12) of 60 V-broken ribbed channel with a constant rib height to hydraulic diameter ratio (e/D) of 0.0625 on the local heat transfer distribution is studied. The Reynolds number based on duct hydraulic diameter is ranging from 10,000 to 30,000. A thin stainless steel foil of 0.05 mm thickness is used as heater and infrared thermography technique is used to obtain the local temperature distribution on the surface. The images are captured in the periodically fully developed region of the channel. It is observed that the heat transfer augmentations in the channel with 90 saw tooth profiled ribs are comparable with those of 90 continuous ribs. The enhancements caused by 60 V-broken ribs are higher than those of 90 continuous ribs. The effect of pitch to the rib height ratio (P/e) is not significant for channel with 60 V-broken ribs for a given rib height to hydraulic diameter ratio (e/D = 0.0625). (author)

  18. Quantitative analysis of rib kinematics based on dynamic chest bone images: preliminary results

    PubMed Central

    Tanaka, Rie; Sanada, Shigeru; Sakuta, Keita; Kawashima, Hiroki

    2015-01-01

    Abstract. An image-processing technique for separating bones from soft tissue in static chest radiographs has been developed. The present study was performed to evaluate the usefulness of dynamic bone images in quantitative analysis of rib movement. Dynamic chest radiographs of 16 patients were obtained using a dynamic flat-panel detector and processed to create bone images by using commercial software (Clear Read BS, Riverain Technologies). Velocity vectors were measured in local areas on the dynamic images, which formed a map. The velocity maps obtained with bone and original images for scoliosis and normal cases were compared to assess the advantages of bone images. With dynamic bone images, we were able to quantify and distinguish movements of ribs from those of other lung structures accurately. Limited rib movements of scoliosis patients appeared as a reduced rib velocity field, resulting in an asymmetrical distribution of rib movement. Vector maps in all normal cases exhibited left/right symmetric distributions of the velocity field, whereas those in abnormal cases showed asymmetric distributions because of locally limited rib movements. Dynamic bone images were useful for accurate quantitative analysis of rib movements. The present method has a potential for an additional functional examination in chest radiography. PMID:26158097

  19. Physical mechanisms of active control of sound transmission through rib stiffened double-panel structure

    NASA Astrophysics Data System (ADS)

    Ma, Xiyue; Chen, Kean; Ding, Shaohu; Yu, Haoxin

    2016-06-01

    This paper presents an analytical investigation on physical mechanisms of actively controlling sound transmission through a rib stiffened double-panel structure using point source in the cavity. The combined modal expansion and vibro-acoustic coupling methods are applied to establish the theoretical model of such active structure. Under the condition of minimizing radiated power of the radiating ribbed plate, the physical mechanisms are interpreted in detail from the point of view of modal couplings similar as that used in existed literatures. Results obtained demonstrate that the rule of sound energy transmission and the physical mechanisms for the rib stiffened double-panel structure are all changed, and affected by the coupling effects of the rib when compared with the analytical results obtained for unribbed double-panel case. By taking the coupling effects of the rib into considerations, the cavity modal suppression and rearrangement mechanisms obtained in existed investigations are modified and supplemented for the ribbed plate case, which gives a clear interpretation for the physical nature involved in the active rib stiffened double-panel structure.

  20. Finite element models of rib as an inhomogeneous beam structure under high-speed impacts.

    PubMed

    Niu, Yuqing; Shen, Weixin; Stuhmiller, James H

    2007-09-01

    Fracture of ribs commonly occurs during blunt impacts and can lead to serious injuries or even fatality. The finite element (FE) modeling of ribs under impacts, however, is difficult due to the complex geometry, the difficulty in determining material parameters, and the amount of the computational time required. This study develops a method of modeling ribs as inhomogeneous beam structures. The geometries are reconstructed from images acquired with X-ray computed tomography. Bone material properties, orthotropic or isotropic, are determined from the CT pixel values. From the material distribution inside the cross-section, generalized classical beam formulations use to determine the local homogenized stiffness of the nodes along the rib. To compare the accuracy and efficiency of the method, detailed three-dimensional (3D) FE models of ribs are also developed. Simulations of three benchmark problems that represent different loading or impact conditions demonstrate that the beam FE model is very efficient and is at least as accurate as a very finely meshed 3D FE model. Finally, the rib FE model is used to study blunt trauma injury of animal tests under high-speed impacts. The consistency between predictions and experimental results shows that the developed rib model is a great value to study of blunt trauma caused by high-speed impacts. PMID:17045511

  1. Vortex generator induced heat transfer augmentation past a rib in a heated duct air flow

    SciTech Connect

    Myrum, T.A.; Acharya, S.; Inamdar, S.; Mehrotra, A. )

    1992-02-01

    The present investigation represents the initial phase of a comprehensive experimental program designed to study the potential for increasing the heat transfer per unit pressure drop in a ribbed duct by positioning vortex generators at key locations in the flow. In particular, the present investigation consists of a rib positioned at the inlet to a rectangular test section with uniform heating at its bottom wall. Local and average Nusselt number results are obtained for a circular rod positioned either immediately above or just downstream of the rib.

  2. Langerhans Cell Histiocytosis of the Rib in an Adult: A Case Report

    PubMed Central

    Kim, Sung Hyun; Choi, Moon Young

    2016-01-01

    Single-site, single-system Langerhans cell histiocytosis (LCH) of the rib is one of the rarest causes of bone tumor in adults. Herein, we report a case of a healthy 35-year-old male who presented with upper back pain that was attributed to a solitary osteolytic lesion at the posterolateral aspect of his sixth rib. For diagnostic confirmation and treatment, partial resection of the sixth rib was performed and pathologic finding was consistent with LCH. At the final follow-up after 2 years, no local recurrence or metastasis was observed. PMID:26933424

  3. Analysis and test of a 16-foot radial rib reflector developmental model

    NASA Technical Reports Server (NTRS)

    Birchenough, Shawn A.

    1989-01-01

    Analytical and experimental modal tests were performed to determine the vibrational characteristics of a 16-foot diameter radial rib reflector model. Single rib analyses and experimental tests provided preliminary information relating to the reflector. A finite element model predicted mode shapes and frequencies of the reflector. The analyses correlated well with the experimental tests, verifying the modeling method used. The results indicate that five related, characteristic mode shapes form a group. The frequencies of the modes are determined by the relative phase of the radial ribs.

  4. Heat transfer and friction characteristics of the microfluidic heat sink with variously-shaped ribs for chip cooling.

    PubMed

    Wang, Gui-Lian; Yang, Da-Wei; Wang, Yan; Niu, Di; Zhao, Xiao-Lin; Ding, Gui-Fu

    2015-01-01

    This paper experimentally and numerically investigated the heat transfer and friction characteristics of microfluidic heat sinks with variously-shaped micro-ribs, i.e., rectangular, triangular and semicircular ribs. The micro-ribs were fabricated on the sidewalls of microfluidic channels by a surface-micromachining micro-electro-mechanical system (MEMS) process and used as turbulators to improve the heat transfer rate of the microfluidic heat sink. The results indicate that the utilizing of micro-ribs provides a better heat transfer rate, but also increases the pressure drop penalty for microchannels. Furthermore, the heat transfer and friction characteristics of the microchannels are strongly affected by the rib shape. In comparison, the triangular ribbed microchannel possesses the highest Nusselt number and friction factor among the three rib types. PMID:25912351

  5. Heat Transfer and Friction Characteristics of the Microfluidic Heat Sink with Variously-Shaped Ribs for Chip Cooling

    PubMed Central

    Wang, Gui-Lian; Yang, Da-Wei; Wang, Yan; Niu, Di; Zhao, Xiao-Lin; Ding, Gui-Fu

    2015-01-01

    This paper experimentally and numerically investigated the heat transfer and friction characteristics of microfluidic heat sinks with variously-shaped micro-ribs, i.e., rectangular, triangular and semicircular ribs. The micro-ribs were fabricated on the sidewalls of microfluidic channels by a surface-micromachining micro-electro-mechanical system (MEMS) process and used as turbulators to improve the heat transfer rate of the microfluidic heat sink. The results indicate that the utilizing of micro-ribs provides a better heat transfer rate, but also increases the pressure drop penalty for microchannels. Furthermore, the heat transfer and friction characteristics of the microchannels are strongly affected by the rib shape. In comparison, the triangular ribbed microchannel possesses the highest Nusselt number and friction factor among the three rib types. PMID:25912351

  6. An In Vitro Deletion in ribE Encoding Lumazine Synthase Contributes to Nitrofurantoin Resistance in Escherichia coli

    PubMed Central

    Vervoort, Jascha; Xavier, Basil Britto; Stewardson, Andrew; Coenen, Samuel; Godycki-Cwirko, Maciek; Adriaenssens, Niels; Kowalczyk, Anna; Lammens, Christine; Harbarth, Stephan; Goossens, Herman

    2014-01-01

    Nitrofurantoin has been used for decades for the treatment of urinary tract infections (UTIs), but clinically significant resistance in Escherichia coli is uncommon. Nitrofurantoin concentrations in the gastrointestinal tract tend to be low, which might facilitate selection of nitrofurantoin-resistant (NIT-R) strains in the gut flora. We subjected two nitrofurantoin-susceptible intestinal E. coli strains (ST540-p and ST2747-p) to increasing nitrofurantoin concentrations under aerobic and anaerobic conditions. Whole-genome sequencing was performed for both susceptible isolates and selected mutants that exhibited the highest nitrofurantoin resistance levels aerobically (ST540-a and ST2747-a) and anaerobically (ST540-an and ST2747-an). ST540-a/ST540-an and ST2747-a (aerobic MICs of >64 μg/ml) harbored mutations in the known nitrofurantoin resistance determinants nfsA and/or nfsB, which encode oxygen-insensitive nitroreductases. ST2747-an showed reduced nitrofurantoin susceptibility (aerobic MIC of 32 μg/ml) and exhibited remarkable growth deficits but did not harbor nfsA/nfsB mutations. We identified a 12-nucleotide deletion in ribE, encoding lumazine synthase, an essential enzyme involved in the biosynthesis of flavin mononucleotide (FMN), which is an important cofactor for NfsA and NfsB. Complementing ST2747-an with a functional wild-type lumazine synthase restored nitrofurantoin susceptibility. Six NIT-R E. coli isolates (NRCI-1 to NRCI-6) from stools of UTI patients treated with nitrofurantoin, cefuroxime, or a fluoroquinolone harbored mutations in nfsA and/or nfsB but not ribE. Sequencing of the ribE gene in six intestinal and three urinary E. coli strains showing reduced nitrofurantoin susceptibility (MICs of 16 to 48 μg/ml) also did not identify any relevant mutations. NRCI-1, NRCI-2, and NRCI-5 exhibited up to 4-fold higher anaerobic MICs, compared to the mutants generated in vitro, presumably because of additional mutations in oxygen

  7. Phrenic Arterial Injury Presenting as Delayed Hemothorax Complicating Simple Rib Fracture

    PubMed Central

    2016-01-01

    Delayed hemothorax after blunt torso injury is rare, but might be associated with significant morbidity and mortality. We present a case of delayed hemothorax bleeding from phrenic artery injury in a 24-year-old woman. The patient suffered from multiple rib fractures on the right side, a right hemopneumothorax, thoracic vertebral injury and a pelvic bone fracture after a fall from a fourth floor window. Delayed hemothorax associated with phrenic artery bleeding, caused by a stab injury from a fractured rib segment, was treated successfully by a minimally invasive thoracoscopic surgery. Here, we have shown that fracture of a lower rib or ribs might be accompanied by delayed massive hemothorax that can be rapidly identified and promptly managed by thoracoscopic means. PMID:27051252

  8. Effect of adiabatic square ribs on natural convection in an asymmetrically heated channel

    NASA Astrophysics Data System (ADS)

    Abidi-Saad, Aissa; Kadja, Mahfoud; Popa, Catalin; Polidori, Guillaume

    2016-06-01

    A 2-D numerical simulation is carried out to investigate the effect of two adiabatic square ribs on laminar flow and heat transfer in an asymmetrically heated channel. The two ribs are symmetrically located on each wall, exactly above the heating zone. The computational procedure is made by solving the unsteady bi-dimensional continuity, momentum and energy equations with the finite volume method. The investigations focused more specifically on the influence of ribs sizes on the flow structure and heat transfer enhancement. The results showed that the variation of ribs sizes significantly alters the heat transfer and fluid flow distribution along the channel, especially in the vicinity of protrusions. Also, the results show that streamlines, isotherms, and the number, sizes and formation of vortex structures inside the channel strongly depend on the size of protrusions. The changes in heat transfer parameters have also been presented.

  9. Chest compressions in an infant with osteogenesis imperfecta type II: No new rib fractures.

    PubMed

    Sewell, R D; Steinberg, M A

    2000-11-01

    The case report of a newborn female with osteogenesis imperfecta type II who underwent cardiopulmonary resuscitation (CPR) with manual chest compressions for several minutes is presented. Chest radiographs taken before and after the chest compressions were administered were reviewed by several radiologists from 3 different hospitals and demonstrated no new radiographically visible rib fractures. Collagen analysis, the patient's clinical appearance, and clinical course, as well as a consultant's opinion aided in confirmation of the diagnosis of osteogenesis imperfecta type II. A review of 4 previous studies concerning rib fractures and CPR is included. This unique case supports previous articles that have concluded that rib fractures rarely, if ever, result from CPR in pediatrics, even in children with a lethal underlying bone disease, such as osteogenesis imperfecta type II. cardiopulmonary resuscitation, chest compressions, osteogenesis imperfecta, rib fractures, bone disease. PMID:11061808

  10. FOCUS SPLITTING ASSOCIATED WITH PROPAGATION OF FOCUSED ULTRASOUND THROUGH THE RIB CAGE.

    PubMed

    Khokhlova, V A; Bobkova, S M; Gavrilov, L R

    2010-09-01

    The effect of focus splitting after propagation of focused ultrasound through a rib cage is investigated theoretically. It is shown that the mechanism of this effect is caused by the interference of waves from two or more spatially separated sources, such as intercostal spaces. Analytical estimates of the parameters of splitting are obtained, i.e., the number of foci, their amplitudes, diameter, and the distance between them, depending on the transducer parameters, as well as the dimensions of the rib cage and position of ribs relative to the radiator. Various configurations of the relative positioning of ribs and radiator are considered; it is shown which of them are the most effective for real surgical operations. PMID:21607120

  11. Schlieren visualization of water natural convection in a vertical ribbed channel

    NASA Astrophysics Data System (ADS)

    Fossa, M.; Misale, M.; Tanda, G.

    2015-11-01

    Schlieren techniques are valuable tools for the qualitative and quantitative visualizations of flows in a wide range of scientific and engineering disciplines. A large number of schlieren systems have been developed and documented in the literature; majority of applications involve flows of gases, typically air. In this work, a schlieren technique is applied to visualize the buoyancy-induced flow inside vertical ribbed channels using water as convective fluid. The test section consists of a vertical plate made of two thin sheets of chrome-plated copper with a foil heater sandwiched between them; the external sides of the plate are roughened with transverse, square-cross-sectioned ribs. Two parallel vertical walls, smooth and unheated, form with the heated ribbed plate two adjacent, identical and asymmetrically heated, vertical channels. Results include flow schlieren visualizations with colour-band filters, reconstructions of the local heat transfer coefficient distributions along the ribbed surfaces and comparisons with past experiments performed using air as working fluid.

  12. Enhancement of upward thermal dissipation in a 16-Chip LED package using ceramic barrier ribs

    NASA Astrophysics Data System (ADS)

    Bang, Young-Tae; Moon, Cheol-Hee

    2013-10-01

    To enhance the upward thermal dissipation characteristics in a 16-chip light emitting diode (LED) package, ceramic barrier ribs were introduced between the LED chips. A FLIR T-250 IR microscopy camera was used to measure the top surface temperature of the package, which decreased from 116°C to 112°C at 2.5W operation because of the ceramic barrier ribs. A finite volume method simulation was conducted to estimate the temperature distribution inside the package, including the junction temperature. This simulation showed that the junction temperature decreased from 119°C to 114°C because of the barrier ribs. This result occurred because the ceramic barrier ribs provided a more effective upward heat dissipation path for the mid-chips, which contributed to the decrease in the junction temperature.

  13. 13. Detail of steel ribs of T18, showing connectin to ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. Detail of steel ribs of T-18, showing connectin to concrete foundation wall - Advance Base Depot Davisville, Building T-17, Ninth Street southeast of Davisville Road, Davisville, Washington County, RI

  14. Expanded-mode semiconductor laser with tapered-rib adiabatic-following fiber coupler

    SciTech Connect

    Vawter, G.A.; Smith, R.E.; Hou, H.; Wendt, J.R.

    1997-02-01

    A new diode laser using a Tapered-Rib Adiabatic-Following Fiber Coupler to achieve 2D mode expansion and narrow, symmetric far-field emission without epitaxial regrowth or sharply-defined tips on tapered waveguides is presented.

  15. Thoracic outlet syndrome caused by hydatid cyst of the first rib-rare but important.

    PubMed

    Levy Faber, Dan; Best, Lael-Anson; Militianu, Daniela; Ben Nun, Alon

    2010-12-01

    Hydatid cysts are usually located in the liver and lungs. Skeletal echinococcosis is relatively rare and that of the rib is exceptional. Less than 50 cases of costal echinococcosis have been reported in the literature so far. To our knowledge, only one case report of thoracic outlet syndrome due to echinococcal cyst in the first rib was described in 1995. Accurate pre-operative diagnosis is important but may be challenging in some cases. Reported here is a case of echinococcosis of the first rib in a young adult who was presented with thoracic outlet syndrome. Plain chest radiograph, CT scan and MRI were performed. The imaging features were suggestive of a solitary aneurysmal bone cyst and the differential diagnosis included echinococcosis of the first rib. The lesion was completely resected and the histopathological examination confirmed the diagnosis of echinococcosis. PMID:22131660

  16. Behavior of streamwise rib vortices in a three-dimensional mixing layer

    NASA Technical Reports Server (NTRS)

    Lopez, J. M.; Bulbeck, C. J.

    1992-01-01

    The structure and behavior of a streamwise rib vortex in a direct numerical simulation of a time-developing three-dimensional incompressible plane mixing layer is examined. Where the rib vortex is being stretched, the vorticity vector is primarily directed in the vortex axial direction and the radial and azimuthal velocity distribution is similar to that of a Burger's vortex. In the region where the vortex stretching is negative, there is a change in the local topology of the vortex. The axial flow is decelerated and a negative azimuthal component of vorticity is induced. These features are characteristic of vortex breakdown. The temporal evolution of the rib vortex is similar to the evolution of an axisymmetric vortex in the early stages of vortex breakdown. The effect of vortex breakdown on other parts of the flow is, however, not as significant as the interaction between the rib vortex and other vortices.

  17. Enhanced reading time efficiency by use of automatically unfolded CT rib reformations in acute trauma.

    PubMed

    Bier, Georg; Schabel, Christoph; Othman, Ahmed; Bongers, Malte N; Schmehl, Jörg; Ditt, Hendrik; Nikolaou, Konstantin; Bamberg, Fabian; Notohamiprodjo, Mike

    2015-11-01

    Rationale of this study was to evaluate whether unfolded rib images enhance time efficiency in detection of rib fractures and time efficiency in patients with acute thoracic trauma. 51 subsequent patients with thoracic trauma underwent 64-slice computed tomography. 1mm thick axial slices were reformatted using a commercially available post-processing software application generating rotatable unfolded rib images. Diagnostic accuracy was evaluated by 3 readers and compared to multiplanar reformations of the original CT images. Reformation and evaluation times were recorded. 116 rib fractures were detected. The multiplanar reformation analysis yielded a sensitivity of 87.9%/93.9%/79.7% with a specificity of 97%/97%/82.2%, whilst the unfolded rib image analysis yielded a sensitivity of 94.8%/94.8%/92.2% and a specificity of 85.2/87.8%/82.4 (p=0.06/0.8/0.04) with high inter-observer agreement (k=0.79-0.85). The mean reading time for the multiplanar reformations was significantly longer (reader 1: 103.7 ± 27.1s/reader 2: 81.8 ± 40.6s/reader 3: 154.3 ± 39.2s) than the evaluation of the unfolded rib images (19.4 ± 4.9s/26.9 ± 15.0s/49.9 ± 18.7s; p<0.01). Concluding, the unfolded rib display reduces reading time for detection of rib fractures in acute thoracic trauma patients significantly and does not compromise the diagnostic accuracy significantly in experienced radiologists. However, unexperienced readers may profit from use of this display. PMID:26226916

  18. Use of a 90° Drill and Screwdriver for Rib Fracture Stabilization

    PubMed Central

    Nickerson, Terry P.; Zielinski, Martin D.; Jenkins, Donald; Schiller, Henry J.

    2016-01-01

    Background Rib fracture stabilization has become a more accepted practice although stabilization of the most cephalad ribs presents a unique challenge. We present our experience with use of a 90° drill and screwdriver to bridge these difficult rib fractures. Methods This retrospective review included patients who underwent rib fracture stabilization from August 1, 2009, through September 30, 2012. Patients were divided into two groups: those whose procedure used the 90° device and those that did not. Data were compared using standard statistical analysis and reported as percentages and medians [interquartile ranges]. P values <0.05 were considered significant. Results We identified 89 patients: 29 (33 %) had 90° devices used and 60 (67 %) did not. There were no differences between groups in age, sex, Trauma-Related Injury Severity Score, the presence of flail chest, occurrence of pneumonia, and intensive care unit or hospital length of stay. The Injury Severity Score was higher in the 90° group (22 vs. 16; P = 0.03). The highest rib stabilized was different between the 2 groups (3 [2–5] vs. 5 [2–9]; P = 0.001), with more third rib stabilizations in the 90° group (38 vs. 20 %; P = 0.04) as well as more total number of ribs fixed (5 vs. 4; P = 0.001). There was no difference in operative time between the 2 groups. Conclusions The surgical reach for rib fracture stabilization has been extended with use of a 90° drill and screwdriver. High fractures under the scapula where access is technically challenging can be stabilized without prolonging operative times. PMID:25403887

  19. Rib suppression in chest radiographs to improve classification of textural abnormalities

    NASA Astrophysics Data System (ADS)

    Hogeweg, Laurens E.; Mol, Christian; de Jong, Pim A.; van Ginneken, Bram

    2010-03-01

    The computer aided diagnosis (CAD) of abnormalities on chest radiographs is difficult due to the presence of overlapping normal anatomy. Suppression of the normal anatomy is expected to improve performance of a CAD system, but such a method has not yet been applied to the computer detection of interstitial abnormalities such as occur in tuberculosis (TB). The aim of this research is to evaluate the effect of rib suppression on a CAD system for TB. Profiles of pixel intensities sampled perpendicular to segmented ribs were used to create a local PCA-based shape model of the rib. The model was normalized to the local background intensity and corrected for gradients perpendicular to the rib. Subsequently rib suppressed images were created by subtracting the models for each rib from the original image. The effect of rib suppression was evaluated using a CAD system for TB detection. Small square image patches were sampled randomly from 15 normal and 35 TB-affected images containing textural abnormalities. Abnormalities were outlined by a radiologist and were given a subtlety rating from 1 to 5. Features based on moments of intensity distributions of Gaussian derivative filtered images were extracted. A supervised learning approach was used to discriminate between normal and diseased image patches. The use of rib suppressed images increased the overall performance of the system, as measured by the area under the receiver operator characteristic (ROC) curve, from 0.75 to 0.78. For the more subtly rated patches (rated 1-3) the performance increased from 0.62 to 0.70.

  20. Atlas-based rib-bone detection in chest X-rays.

    PubMed

    Candemir, Sema; Jaeger, Stefan; Antani, Sameer; Bagci, Ulas; Folio, Les R; Xu, Ziyue; Thoma, George

    2016-07-01

    This paper investigates using rib-bone atlases for automatic detection of rib-bones in chest X-rays (CXRs). We built a system that takes patient X-ray and model atlases as input and automatically computes the posterior rib borders with high accuracy and efficiency. In addition to conventional atlas, we propose two alternative atlases: (i) automatically computed rib bone models using Computed Tomography (CT) scans, and (ii) dual energy CXRs. We test the proposed approach with each model on 25 CXRs from the Japanese Society of Radiological Technology (JSRT) dataset and another 25 CXRs from the National Library of Medicine CXR dataset. We achieve an area under the ROC curve (AUC) of about 95% for Montgomery and 91% for JSRT datasets. Using the optimal operating point of the ROC curve, we achieve a segmentation accuracy of 88.91±1.8% for Montgomery and 85.48±3.3% for JSRT datasets. Our method produces comparable results with the state-of-the-art algorithms. The performance of our method is also excellent on challenging X-rays as it successfully addressed the rib-shape variance between patients and number of visible rib-bones due to patient respiration. PMID:27156048

  1. A Study on the Performance of the Split Reaction Water Turbine with Guide Ribs

    NASA Astrophysics Data System (ADS)

    Allen, Deuel H.; Villanueva, Eliseo P.

    2015-09-01

    The development of technologies that make use of renewable energy is of great significance presently. A new kind of turbine called Split Reaction Water Turbine (SRWT) using PVC pipes as material is a major contribution towards harnessing the energy potentials of small stream low head water resources. SRWTs of diameter to height ratio (D/H = 110 cm/160 cm) were tested at the MSU-IIT College of Engineering Fluid Engineering Laboratory. Data on volumetric flow and pressure head at the turbine inlet of the SRWT were recorded using National Instrument Data Processing System using LabView software. In later experiments, guide ribs were installed at the vane of the exit nozzles in order to determine the difference in the performance of the ribbed and the non-ribbed SRWT. Simulations of the running SRWT were conducted using SOLIDWORKS software. Results of the simulations aided in the thorough analyses of the data from the experimental runs. A comparison of data from the ribbed and non-ribbed SRWT shows that guide ribs were effective in directing the momentum of the exiting water to improve the speed of rotation. In this study, the increase in the speed of the Split Reaction Water Turbine was as much as 46%.

  2. Possible Function of the ribT Gene of Bacillus subtilis: Theoretical Prediction, Cloning, and Expression.

    PubMed

    Yakimov, A P; Seregina, T A; Kholodnyak, A A; Kreneva, R A; Mironov, A S; Perumov, D A; Timkovskii, A L

    2014-07-01

    The complete decipherment of the functions and interactions of the elements of the riboflavin biosynthesis operon (rib operon) of Bacillus subtilis are necessary for the development of superproducers of this important vitamin. The function of its terminal ribT gene has not been established to date. In this work, a search for homologs of the hypothetical amino acid sequence of the gene product through databases, as well as an analysis of the homolgs, was performed; the distribution of secondary structure elements was theoretically predicted; and the tertiary structure of the RibT protein was proposed. The ribT gene nucleotide sequence was amplified and cloned into the standard high-copy expression vector pET15b and then expressed after induction with IPTG in E. coli BL21 (DE3) strain cells containing the inducible phage T7 RNA polymerase gene. The ribT gene expression was confirmed by SDS-PAGE. The protein product of the expression was purified by affinity chromatography. Therefore, the real possibility of RibT protein production in quantities sufficient for further investigation of its structure and functional activity was demonstrated. PMID:25349719

  3. Heat Transfer Characteristics and Reynolds Stress Budgets in Single-Rib Mounting Channel

    NASA Astrophysics Data System (ADS)

    Miura, Takahiro; Matsubara, Koji; Sakurai, Atsushi

    Heat transfer and fluid flow in a single-rib mounting channel were investigated by directly solving Navier-Stokes and energy equations. Flow and thermal fields were considered to be fully developed at the inlet of the channel, and the simulation was made for spatial advancement of turbulent heat transfer. Keeping the frictional Reynolds number, Reτ0, at 150, the rib height ratio was changed in four steps from H/δ = 0.05 to H/δ = 0.4. Computational results were confirmed to be nearly independent of grid meshes. In addition, numerical accuracy was confirmed through close agreement between computed mean pressure and the experiment by Yao et al. (1995). The numerical results revealed that the highest value of the mean Nusslet number was as large as 1.3 times the smooth surface consuming the same pumping power, and the local enhancement of heat transfer was correlated with the turbulence increase near the rib front and the reattachment point. According to the Reynolds stress budgets for H/δ = 0.2, there were mechanisms to induce powerful fluctuations: (1) Streamwise fluctuation was increased through production by flow deceleration in the upstream of the rib; (2) Redistribution to wall-normal and spanwise fluctuations was fortified by the fluid splattering to the rib front. Therefore, excellent performance of heat transfer was concluded to occur due to flow structures, which induce the strong disturbance near the rib front triggering smooth transition of the separated shear layer.

  4. A comparison of methods for focusing the field of a HIFU array transducer through human ribs

    NASA Astrophysics Data System (ADS)

    Gélat, P.; ter Haar, G.; Saffari, N.

    2014-06-01

    A forward model, which predicts the scattering by human ribs of a multi-element high-intensity focused ultrasound transducer, was used to investigate the efficacy of a range of focusing approaches described in the literature. This forward model is based on the boundary element method and was described by Gélat et al (2011 Phys. Med. Biol. 56 5553-81 2012 Phys. Med. Biol. 57 8471-97). The model has since been improved and features a complex surface impedance condition at the surface of the ribs. The inverse problem of focusing through the ribs was implemented on six transducer array-rib topologies and five methods of focusing were investigated, including spherical focusing, binarized apodization based on geometric ray tracing, phase conjugation and the decomposition of the time-reversal operator method. The excitation frequency was 1 MHz and the array was of spherical-section type. Both human and idealized rib topologies were considered. The merit of each method of focusing was examined. It was concluded that the constrained optimization approach offers greater potential than the other focusing methods in terms of maximizing the ratio of acoustic pressure magnitudes at the focus to those on the surface of the ribs whilst taking full advantage of the dynamic range of the phased array.

  5. Regional Variation in the Structural Response and Geometrical Properties of Human Ribs

    PubMed Central

    Cormier, Joseph M.; Stitzel, Joel D.; Duma, Stefan M.; Matsuoka, Fumio

    2005-01-01

    By incorporating material and geometrical properties into a model of the human thorax one can develop an injury criterion that is a function of stress and strain of the material and not a function of the global response of the thorax. Previous research on the mechanical properties of ribs has focused on a limited set of specific ribs. For this study a total of 52 rib specimens were removed from four cadaver subjects. Variation in peak moment by thoracic region was significant (p < 0.01) with average values of 2, 2.9 and 3.9 N-m for the anterior, lateral and posterior regions respectively. Two geometrical properties, radius of gyration and distance from the neutral axis, showed significant variation by region (p < 0.0001) as well as by rib level (p = < 0.01, 0.05). The results of this study can be used to update current models of the human thorax to account for the variation in strength and geometrical properties throughout the rib cage. Accounting for the variation in rib properties by region will improve injury predictive measures and, therefore, the ability to design systems to prevent thoracic injury. PMID:16179146

  6. Belt-rib concept for variable-camber airfoils: recent developments

    NASA Astrophysics Data System (ADS)

    Campanile, Lucio F.; Seack, Oliver; Sachau, Delf

    2000-06-01

    The belt-rib concept for lifting surfaces with variable camber evolved at DLR recently as one of the most promising solutions for the adaptive wing. With the belt-rib idea the adaptive wing issue is approached in a new way: instead of a 'mechatronic' solution with hinges or linear bearings a 'structronic' solution is chosen, where defined, distributed flexibility allow the desired shape changes. The new concept evolves from the classical wing structure. The classical rib, which is in charge of the wing section's stiffness, is replaced by a 'belt rib,' which allows camber changes within given limits while leaving the remaining in-plane stiffness properties of the section widely unchanged. The evolution of the belt-rib concept was accompanied by experimental tests on different prototypes. The last developments concern the construction of a model with solid-state hinges, realized as hybrid glass fiber -- carbon-fiber reinforced composite structure. The model is actuated mechanically by Bowden cables, which can be replaced by shape memory wires in the next development stage. In this paper, the fundamentals of the concept and the most relevant results of the first developments are reported. A description of the new belt-rib design follows, which was implemented in a new prototype. The description of the experimental strength proof and an outline of further development work conclude the paper.

  7. Regional effects of ovariectomy and cadmium on bone mineral in ribs from aged female beagles

    SciTech Connect

    Hurst, D.R. . Dept. of Zoology)

    1991-01-01

    The purpose of this study was to evaluate effects of estrogen depletion and cadmium (Cd) on bone calcium and to determine if these effects were localized in specific regions of ribs. Fourteen female beagles with {sup 45}Ca labeled skeletons were divided into four groups: sham controls (SO{minus}); ovariectomized (OV{minus}); shams exposed to Cd (SO+); ovariecomized exposed to Cd (OV+). Total Cd exposure period was 7 months, including 1 month by capsules and 6 months by drinking H{sub 2}O. Ribs were taken at necropsy from 12 of the 14 dogs, and each rib was quartered. Wet, dry, and ash weights, as well as total Ca and {sup 45}Ca content, were determined for each quarter. Analysis of ribs from control animals demonstrated that a given rib is heterogeneous in composition. One end appears to be less mineralized and more metabolically active than other regions. The OV{minus} and OV+ mid-rib regions had significantly lower dry and ash weights than SO{minus}. Total Ca contents of these same regions were also decreased in the OV{minus} and OV+. The only significant change in Ca/dry and Ca/ash was observed when comparing OV+ to SO{minus}. Analysis of treatment suggests that there are regional effects following ovariectomy increased the loss of bone mineral occurring as a result of ovariectomy. 30 refs., 1 fig.

  8. The ribB FMN riboswitch from Escherichia coli operates at the transcriptional and translational level and regulates riboflavin biosynthesis.

    PubMed

    Pedrolli, Danielle; Langer, Simone; Hobl, Birgit; Schwarz, Julia; Hashimoto, Masayuki; Mack, Matthias

    2015-08-01

    FMN riboswitches are genetic elements that, in many bacteria, control genes responsible for biosynthesis and/or transport of riboflavin (vitamin B2 ). We report that the Escherichia coli ribB FMN riboswitch controls expression of the essential gene ribB coding for the riboflavin biosynthetic enzyme 3,4-dihydroxy-2-butanone-4-phosphate synthase (RibB; EC 4.1.99.12). Our data show that the E. coli ribB FMN riboswitch is unusual because it operates at the transcriptional and also at the translational level. Expression of ribB is negatively affected by FMN and by the FMN analog roseoflavin mononucleotide, which is synthesized enzymatically from roseoflavin and ATP. Consequently, in addition to flavoenzymes, the E. coli ribB FMN riboswitch constitutes a target for the antibiotic roseoflavin produced by Streptomyces davawensis. PMID:25661987

  9. Dosemetric Parameters Predictive of Rib Fractures after Proton Beam Therapy for Early-Stage Lung Cancer.

    PubMed

    Ishikawa, Yojiro; Nakamura, Tatsuya; Kato, Takahiro; Kadoya, Noriyuki; Suzuki, Motohisa; Azami, Yusuke; Hareyama, Masato; Kikuchi, Yasuhiro; Jingu, Keiichi

    2016-01-01

    Proton beam therapy (PBT) is the preferred modality for early-stage lung cancer. Compared with X-ray therapy, PBT offers good dose concentration as revealed by the characteristics of the Bragg peak. Rib fractures (RFs) after PBT lead to decreased quality of life for patients. However, the incidence of and the risk factors for RFs after PBT have not yet been clarified. We therefore explored the relationship between irradiated rib volume and RFs after PBT for early-stage lung cancer. The purpose of this study was to investigate the incidence and the risk factors for RFs following PBT for early-stage lung cancer. We investigated 52 early-stage lung cancer patients and analyzed a total of 215 irradiated ribs after PBT. Grade 2 RFs occurred in 12 patients (20 ribs); these RFs were symptomatic without displacement. No patient experienced more severe RFs. The median time to grade 2 RFs development was 17 months (range: 9-29 months). The three-year incidence of grade 2 RFs was 30.2%. According to the analysis comparing radiation dose and rib volume using receiver operating characteristic curves, we demonstrated that the volume of ribs receiving more than 120 Gy3 (relative biological effectiveness (RBE)) was more than 3.7 cm(3) at an area under the curve of 0.81, which increased the incidence of RFs after PBT (P < 0.001). In this study, RFs were frequently observed following PBT for early-stage lung cancer. We demonstrated that the volume of ribs receiving more than 120 Gy3 (RBE) was the most significant parameter for predicting RFs. PMID:27087118

  10. Stress profile of infant rib in the setting of child abuse: A finite element parametric study.

    PubMed

    Tsai, Andy; Coats, Brittany; Kleinman, Paul K

    2012-07-26

    The primary goal of this study is to advance our current understanding of infant rib injuries in the setting of child abuse. To this end, we employed finite element model simulations to determine the sensitivity of an infant rib's stress response to varying material properties and under varying degrees of anterior-posterior chest compression. Using high-resolution chest CT images obtained from a 6-day-old infant, we constructed a simplified geometric model consisting of bone and cartilage structures. To simulate the lateral gripping of an infant in child abuse, an anterior-posterior chest compression load was applied to cause increased stresses along the costovertebral articulation, a classic site for inflicted rib fractures. A sensitivity analysis was conducted to quantify the effects of varying Young's modulus and Poisson's ratio of the bones and cartilages. In addition, we varied the amount of anterior-posterior chest displacement to assess the sensitivity of this parameter to the rib's stress profile. We found that varying Young's modulus of the bone and cartilage not only changed the magnitude but also the shape profile of the rib's stress response. In contrast, varying the degree of chest compression only changed the magnitude of the stress response and not the shape profile. We also discovered that by varying Poisson's ratio of the bone and cartilage, no appreciable change was seen in the magnitude or the shape profile of the rib's stress response. Finite element modeling shows promise as a tool to elucidate the mechanisms of rib fractures in abused infants. PMID:22727522

  11. A study of ribbing effect on the vibration response and transmission of an L-shaped plate.

    PubMed

    Lin, Tian Ran; Tan, Jiwen; Zhou, Yifan; Jiang, Jingliang; Zhang, Kai

    2016-06-01

    This paper presents an analytical solution for the vibration response of a ribbed L-shaped plate using a modal expansion solution approach. The analytical model is then employed to study the ribbing effect on vibration reduction and transmission between the two plate components of the L-shaped plate. It is found that for the system considered in the study, a rib inserted between the excitation force and the source plate can lead to a large vibration reduction for both source and receiving plates except at a frequency band near the fundamental resonant frequency of the rib where the rib's flexural stiffness is negligible. A reduced vibration transmission to the receiving plate can also be achieved by placing a rib near the plate/plate junction, attributed to the increased moment impedance at the coupling after the rib insertion. Increasing the rib's flexural stiffness under this condition can further reduce vibration transmission in the low frequency bands while increasing the rib's mass can lead to a reduced vibration transmission in the higher frequency bands. The insights obtained from this study are relevant to vibration control of structures such as transformer tanks and machine covers. PMID:27369128

  12. Heat transfer in a two-pass internally ribbed turbine blade coolant channel with cylindrical vortex generators

    SciTech Connect

    Hibbs, R.; Chen, Y.; Nikitopoulos, D.

    1995-10-01

    The effect of vortex generators on the mass (heat) transfer from the ribbed passage of a two pass turbine blade coolant channel is investigated with the intent of optimizing the vortex generator geometry so that significant enhancements in mass/heat transfer can be achieved. In the experimental configuration considered, ribs are mounted on two opposite walls; all four walls along each pass are active and have mass transfer from their surfaces but the ribs are non-participating. Mass transfer measurements, in the form of Sherwood number ratios, are made along the centerline and in selected inter-rib modules. Results are presented for Reynolds number in the range of 5,000 to 40,000, pitch to rib height ratios of 10.5 and 21, and vortex generator-rib spacing to rib height ratios of 0.55, and 1.5. Centerline and spanwise averaged Sherwood number ratios are presented along with contours of the Sherwood number ratios. Results indicate that the vortex generators induce substantial increases in the local mass transfer rates, particularly along the side walls, and modest increases in the average mass transfer rates. The vortex generators have the effect of making the inter-rib profiles along the ribbed walls more uniform. Along the side walls, horse-shoe vortices that characterize the vortex generator wake are associated with significant mass transfer enhancements. The wake effects and the levels of enhancement decrease somewhat with increasing Reynolds number and decreasing pitch.

  13. Malformations of the vertebral bodies and the ribs associated to spinal dysraphism without spina bifida in a Pekingese dog.

    PubMed

    Ruberte, J; Añor, S; Carretero, A; Vilafranca, M; Navarro, M; Mascort, J; Pumarola, M

    1995-07-01

    A Pekingese dog with hemivertebrae, rib malformations and spinal cord dysraphism without spina bifida was presented. Two types of hemivertebrae were seen: bilateral and unilateral. Thoracic hemivertebrae were associated with fused ribs and rudimentary ribs. Spinal dysraphism consisted of polycavitary syringomyelia in the dorsal and lateral funiculi, hydromyelia and anomalies of the dorsal median septum and median fissure, associated to lumbar and sacral hemivertebrae. Cauda equina agenesia was also present. To conclude, the dog showed two malformations from different embryonic origins. Vertebral and rib malformations are of mesodermic origin and spinal dysraphism is of ectodermic origin. A possible common mechanism responsible for both anomalies is discussed. PMID:8578905

  14. Heat transfer in a two-pass internally ribbed turbine blade coolant channel with cylindrical vortex generators

    SciTech Connect

    Hibbs, R.; Acharya, S.; Chen, Y.

    1995-12-31

    The effect of vortex generators on the mass (heat) transfer from the ribbed passage of a two pass turbine blade coolant channel is investigated with the intent of optimizing the vortex generator geometry so that significant enhancements in mass/heat transfer can be achieved. In the experimental configuration considered, ribs are mounted on two opposite walls; all four walls along each pass are active and have mass transfer from their surfaces but the ribs are non-participating. Mass transfer measurements, in the form of Sherwood number ratios, are made along the centerline and in selected inter-rib modules. Results are presented for Reynolds number in the range of 5,000 to 40,000, pitch to rib height ratios of 10.5 and 21, and vortex generator-rib spacing to rib height ratios of 0.55, and 1.5. Centerline and spanwise averaged Sherwood number ratios are presented along with contours of the Sherwood number ratios. Results indicate that the vortex generators induce substantial increases in the local mass transfer rates, particularly along the side walls, and modest increases in the average mass transfer rates. The vortex generators have the effect of making the inter-rib profiles along the ribbed walls more uniform. Along the side walls, horse-shoe vortices that characterize the vortex generator wake are associated with significant mass transfer enhancements. The wake effects and the levels of enhancement decrease somewhat with increasing Reynolds number and decreasing pitch.

  15. Combined effects of rotation and rib-roughness - a dns study of turbulent channel flow

    NASA Astrophysics Data System (ADS)

    Andersson, Helge I.; Narasimhamurthy, Vagesh D.

    2014-11-01

    The combined effects of system rotation and rib-roughness on turbulent channel flow have been investigated by means of direct numerical simulations. Square ribs were placed on both walls in a non-staggered arrangement and the channel was subjected to steady rotation about a spanwise axis for a series of rotation numbers up to Ro = 24. A pressure-loss reduction of about 20 per cent resulted from the imposed rotation at Ro = 6. In spite of the 10 per cent blockage due to the wall-mounted ribs, the flow field exhibited statistical streamwise homogeneity in the core region. The mean velocity varied linearly with a slope such that the mean fluid rotation exactly outweighed the imposed system rotation. The flow field in the vicinity of the ribs was affected differently at the two sides of the rotating channel. The separated flow region behind the ribs on the anti-cyclonic pressure side shrinked with increasing Ro due to the enhanced turbulent mixing caused by the Coriolis force. The original d-type roughness was thus turned into a k-type roughness.

  16. IGRT/ART phantom with programmable independent rib cage and tumor motion

    SciTech Connect

    Haas, Olivier C. L.; Mills, John A.; Land, Imke; Mulholl, Pete; Menary, Paul; Crichton, Robert; Wilson, Adrian; Sage, John; Anna, Morenc; Depuydt, Tom

    2014-02-15

    Purpose: This paper describes the design and experimental evaluation of the Methods and Advanced Equipment for Simulation and Treatment in Radiation Oncology (MAESTRO) thorax phantom, a new anthropomorphic moving ribcage combined with a 3D tumor positioning system to move target inserts within static lungs. Methods: The new rib cage design is described and its motion is evaluated using Vicon Nexus, a commercial 3D motion tracking system. CT studies at inhale and exhale position are used to study the effect of rib motion and tissue equivalence. Results: The 3D target positioning system and the rib cage have millimetre accuracy. Each axis of motion can reproduce given trajectories from files or individually programmed sinusoidal motion in terms of amplitude, period, and phase shift. The maximum rib motion ranges from 7 to 20 mm SI and from 0.3 to 3.7 mm AP with LR motion less than 1 mm. The repeatability between cycles is within 0.16 mm root mean square error. The agreement between CT electron and mass density for skin, ribcage, spine hard and inner bone as well as cartilage is within 3%. Conclusions: The MAESTRO phantom is a useful research tool that produces programmable 3D rib motions which can be synchronized with 3D internal target motion. The easily accessible static lungs enable the use of a wide range of inserts or can be filled with lung tissue equivalent and deformed using the target motion system.

  17. Holographic interferometry as a method to detect welding failures on ribbed iron structures

    NASA Astrophysics Data System (ADS)

    Vincitorio, F. M.; Budini, N.; Mulone, C.; Freyre, C.; Spector, M.; López Díaz, A. J.; Ramil Rego, A.; Yañez Casal, A.

    2013-11-01

    Metallic structures made of ribbed iron bars (ADN-420) are of common use in sheds and supporting structures. Usually, trusses are constructed with many pieces of ribbed iron bars, combined together through a welding process. Although ribbed iron manufacturers do not recommend this type of structure it is still frequently used. The main weakness of these trusses is the welding point because ribbed iron is not a material suitable for welding. This work presents results obtained from an analysis of welding points between ribbed iron bars extracted from a collapsed truss, by means of conventional (optical) and digital holographic interferometry (HI and DHI, respectively). The experiments were divided in two different series of studies. The first series were performed by HI on metallographic samples while the second series were done by DHI on different welding points. These results were complemented by metallographic analysis made in an external laboratory. DHI indicated that the bars did not have important failures but evidenced defects in one of the welding points under analysis. This information together with metallographic results allowed inferring that the collapse was probably due to an error in the design of the structure, since the iron bars were out of standard compliance.

  18. First-rib stress fracture in two adolescent swimmers: a case report.

    PubMed

    Low, Sara; Kern, Michael; Atanda, Alfred

    2016-07-01

    First-rib stress fractures have been described in adolescent athletes in various sports, with only one prior case report of first-rib stress fractures in an adolescent female swimmer. There is a need for research on the cause, management, and prevention of these injuries as they lead to significant morbidity and critical time away from sport for these aspiring athletes. We aimed to describe first-rib stress fractures as a potential cause for non-specific atraumatic chronic shoulder pain in adolescent swimmers and to discuss the different presentations, unique risk factors, treatment, and potential injury prevention strategies of such fractures. We discussed two such cases which were successfully treated with activity modification with restriction of all overhead activity, gradually progressive physical therapy and a return to swimming protocol. First-rib stress fractures can vary in presentation and should be in the differential diagnosis in adolescent swimmers with chronic shoulder pain. These injuries can be successfully managed with rest from overhead activities and physical therapy. Gradual return to competitive swimming can be achieved even with non-union of a first-rib stress fracture. Emphasis on balanced strength training in different muscle groups and proper swimming technique is essential to prevent these injuries. PMID:26539736

  19. Effect of ribs in HIFU beam path on formation of coagulative necrosis in goat liver

    NASA Astrophysics Data System (ADS)

    Li, Faqi; Gong, Xiaobo; Hu, Kai; Li, Chongyan; Wang, Zhibiao

    2006-05-01

    The motives of the work are to explore the effect of ribs in HIFU beam path on HIFU ablation goat liver. A model-JC Focused Ultrasound Tumor Therapeutic System was used. A 0.75 MHz focused transducer with 150mm aperture and 120mm focal length was used in all experiment. Acoustical power can be adjusted. 30 goats were divided into control group (HIFU beam through rib cage, HIFU alone), experiment group 1(HIFU beam through rib cage, HIFU combined with microbubble) and experiment group 2(Ribs in HIFU beam path were surgically removed, HIFU alone). 20 targeted regions at 5cm away from skin surface were applied for creating necrosis with linear scanning of 15mm length using HIFU in 3 groups. All animals were sacrificed two days later and exposed organs were dissected. After obtaining the maximal section, the volumes of the necrotic regions were measured, then to calculate Energy Efficiency Factor (EEF). Researched results showed that Ribs in HIFU beam path affected the formation of coagulative necrosis and enhanced EEF in control group. HIFU combined with microbubble could enhance the formation of coagulative necrosis and decrease EEF.

  20. Turbulent-Heat-Flux and Temperature-Variance Budgets in a Single-Rib Mounting Channel

    NASA Astrophysics Data System (ADS)

    Miura, Takahiro; Matsubara, Koji; Sakurai, Atsushi

    Heat transfer and fluid flow in a single-rib mounting channel were investigated by directly solving Navier-Stokes and energy equations. The flow and thermal fields were considered to be fully developed at the inlet of the channel, and the simulation was made for spatial advancement of turbulent heat transfer. The Reynolds number based on the friction velocity at the inlet and the channel half width was 150. The Prandtl number was 0.71. The budgets for turbulent heat fluxes and temperature variance at various sections were presented and were investigated, which would be useful for testing and developing turbulence models. Near a circular vortex in front of the rib, pressure diffusion terms made an important contribution. Remarkable production terms were generated near a reattachment point. Production and dissipation terms were not dominant in front of and above the rib, and a time scale ratio exceeded 2.0 in the region.

  1. Glued Joint Behavior of Ribs for Wood-Based Composite Plates

    NASA Astrophysics Data System (ADS)

    Frolovs, G.; Rocens, K.; Sliseris, J.

    2015-11-01

    This article presents experimental investigations of composite sandwich plywood plates with cell type core and their connections between skin layers of birch plywood and a core of straight and curved plywood honeycomb-type ribs. This shape of core ribs provides several improvements for these plates in the manufacturing process as well as improves the mechanical properties of plywood plates. This specific form of ribs allows simplifying the manufacturing of these plates although it should be detailed and improved. The most typical cases (series of specimens) were compared to the results obtained from FEM (ANSYS) simulations. All thicknesses of elements are chosen according to plywood supplier assortment. Standard birch plywood (Riga Ply) plates were used - three layer plywood was chosen for skin elements (Surfaces) and three or five layer plywood was chosen for edge elements. Different bond pressures were taken to compare their influence on joint strength and stiffness.

  2. Correlation of Near-Wall Turbulence Structures with Heat Transfer in Ribbed-Pipe Flow

    NASA Astrophysics Data System (ADS)

    Ahn, Hyungsu; Kang, Changwoo; Yang, Kyung-Soo; Park, Doohyun

    2015-11-01

    Ribbed-pipe flow is one of the most commonly used flow configurations to enhance heat transfer, albeit, at the expense of increased pressure drop. The ribs mounted on the pipe wall differently alter the flow depending on the pitch, the distance between two neighboring ribs. When the pitch is short, fluid is trapped inside grooves, resulting in a low heat-transfer rate. When the pitch is long enough, however, the ribs disturb the flow by shedding vortices, resulting in heat-transfer enhancement. We aim at elucidating the correlation of near-wall turbulence induced by the shed vortices with the increased heat-transfer rate on the ribbed-pipe wall. Our analysis is based on our LES data base obtained for Re =24,000, Pr =0.71, PR(pitch ratio) =2, 4, 6, 8, 10, 18, BR(blockage ratio) =0.0625. Here, the bulk velocity and the pipe diameter are used as the velocity and length scales, respectively. Our presentation focuses on the near-wall distributions of the higher-order turbulence statistics including but not limited to rms of temperature fluctuation, cross-correlations, rms of vorticity, and turbulent heat fluxes. Octants and JPDF are also presented in order to clarify the prevailing heat-transfer mechanism in the immediate vicinity of the ribbed-pipe wall. This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP) (No. 2015R1A2A2A01002981).

  3. Biomechanical investigation of impact induced rib fractures of a porcine infant surrogate model.

    PubMed

    Blackburne, William B; Waddell, J Neil; Swain, Michael V; Alves de Sousa, Ricardo J; Kieser, Jules A

    2016-09-01

    This study investigated the structural, biomechanical and fractographic features of rib fractures in a piglet model, to test the hypothesis that fist impact, apart from thoracic squeezing, may result in lateral costal fractures as observed in abused infants. A mechanical fist with an accelerometer was constructed and fixed to a custom jig. Twenty stillborn piglets in the supine position were impacted on the thoracic cage. The resultant force versus time curves from the accelerometer data showed a number of steps indicative of rib fracture. The correlation between impact force and number of fractures was statistically significant (Pearson׳s r=0.528). Of the fractures visualized, 15 completely pierced the parietal pleura of the thoracic wall, and 5 had butterfly fracture patterning. Scanning electron microscopy showed complete bone fractures, at the zone of impact, were normal to the axis of the ribs. Incomplete vertical fractures, with bifurcation, occurred on the periphery of the contact zone. This work suggests the mechanism of rib failure during a fist impact is typical of the transverse fracture pattern in the anterolateral region associated with cases of non-accidental rib injury. The impact events investigated have a velocity of ~2-3m/s, approximately 2×10(4) times faster than previous quasi-static axial and bending tests. While squeezing the infantile may induce buckle fractures in the anterior as well as posterior region of the highly flexible bones, a fist punch impact event may result in anterolateral transverse fractures. Hence, these findings suggest that the presence of anterolateral rib fractures may result from impact rather than manual compression. PMID:27310573

  4. RIB in-flight production and the facility EXOTIC at LNL

    SciTech Connect

    Mazzocco, Marco

    2014-05-09

    The production of Radioactive Ion Beams (RIBs) via the In-Flight technique is reviewed. This separation method typically employs four main production mechanisms: (i) Projectile Fragmentation; (ii) Projectile Fission; (iii) Nuclear Fusion and (iv) Direct Processes in Inverse Kinematics. We will concentrate particularly on the last mechanism, the one used by the facility EXOTIC at the INFN-Laboratori Nazionali di Legnaro (LNL) for the production of light RIBs. An extensive description of the facility and a brief overview of the most recent scientific achievements with {sup 7}Be and {sup 17}F are given.

  5. Vertical expandable prosthetic titanium rib (VEPTR): a review of indications, normal radiographic appearance and complications.

    PubMed

    Parnell, Shawn E; Effmann, Eric L; Song, Kit; Swanson, Jonathon O; Bompadre, Viviana; Phillips, Grace S

    2015-04-01

    Vertical expandable prosthetic titanium rib (VEPTR) is increasingly used in the treatment of thoracic insufficiency, idiopathic and neuromuscular scoliosis and chest wall defects in children. In contrast to spinal fusion surgery, the VEPTR allows for growth while stabilizing the deformity. We illustrate the common indications and normal radiographic appearance of the three common configurations of VEPTR (cradle-to-cradle assembly, cradle with lumbar extension assembly, cradle-to-ala hook assembly). There is a relatively high rate of reported complications with VEPTR in the literature. We discuss the potential complications of VEPTR, including infection, rib fracture, dislodged hardware and neurological injury, with an emphasis on imaging diagnosis. PMID:25241040

  6. Experimental investigation of MBE GaAs rib waveguides at 10.6 microns

    NASA Astrophysics Data System (ADS)

    Sarkis, R. G.; Larson, D. C.; Jenkinson, H. A.

    1989-10-01

    Results are evaluated from recent investigations of the performance of n/n(+)-GaAs rib waveguides fabricated by MBE and reactive-ion etching. A simple, 'effective index' analysis method is used to predict bound-mode propagation constants; a comparison with alternative analyses shows the method to be sufficiently accurate for the geometries in question. Intensity curves are obtained experimentally as a function of incident angle, for correlation with theoretical, lower-order modes. A prism-coupling approach is developed which not only allows experimenters to excite and observe the bands of a rib waveguide, but to empirically determine their values.

  7. Use of a Vertical Expandable Prosthetic Titanium Rib in Children With Thoracic Insufficiency Syndrome and Scoliosis.

    PubMed

    Watts, Stephanie L

    2016-04-01

    Thoracic insufficiency syndrome is the inability of the thorax to support normal respiration or lung growth. One treatment to address the thoracic deformities associated with the syndrome is placement of a vertical expandable prosthetic titanium rib. The goal is to restore thoracic volume, symmetry, and function and to allow for growth of the thorax in skeletally immature children. The main topics include indications for placement of a titanium rib, postoperative nursing care, potential complications, long-term follow-up, quality-of-life issues, and implications for critical care nurses and advanced practice nurses. (Critical Care Nurse.2016;36[2]:52-61). PMID:27037339

  8. Microbiological safety of commercial prime rib preparation methods: thermal inactivation of Salmonella spp. in mechanically tenderized beef roasts

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A survey of food service operations in a medium-size Midwestern city was conducted to evaluate the microbiological safety of prime rib preparation methods relative to survival of Salmonella spp. in both intact and tenderized (non-intact) product. All six restaurants visited seared rib eye roasts (ai...

  9. Automatic segmentation of lung parenchyma based on curvature of ribs using HRCT images in scleroderma studies

    NASA Astrophysics Data System (ADS)

    Prasad, M. N.; Brown, M. S.; Ahmad, S.; Abtin, F.; Allen, J.; da Costa, I.; Kim, H. J.; McNitt-Gray, M. F.; Goldin, J. G.

    2008-03-01

    Segmentation of lungs in the setting of scleroderma is a major challenge in medical image analysis. Threshold based techniques tend to leave out lung regions that have increased attenuation, for example in the presence of interstitial lung disease or in noisy low dose CT scans. The purpose of this work is to perform segmentation of the lungs using a technique that selects an optimal threshold for a given scleroderma patient by comparing the curvature of the lung boundary to that of the ribs. Our approach is based on adaptive thresholding and it tries to exploit the fact that the curvature of the ribs and the curvature of the lung boundary are closely matched. At first, the ribs are segmented and a polynomial is used to represent the ribs' curvature. A threshold value to segment the lungs is selected iteratively such that the deviation of the lung boundary from the polynomial is minimized. A Naive Bayes classifier is used to build the model for selection of the best fitting lung boundary. The performance of the new technique was compared against a standard approach using a simple fixed threshold of -400HU followed by regiongrowing. The two techniques were evaluated against manual reference segmentations using a volumetric overlap fraction (VOF) and the adaptive threshold technique was found to be significantly better than the fixed threshold technique.

  10. CHEMICALLY-INDUCED LUMBAR RIBS IN CD-1 MICE; SIZE DISTRIBUTION AND DOSE-RESPONSE

    EPA Science Inventory

    Supernumerary ribs (SNR) of differing sizes are common observations in rodent developmental toxicty studies, and the significance of treatment-related increases in SNR in standard studies has been contentious. We induced dose-related increases in SNR in CD-1 mice by treating on g...

  11. EFFECTS OF FORAGE SPECIES ON RIB COMPOSITION, COLOR, AND PALATABILITY IN FORAGE-FINISHED BEEF

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Forty-seven Angus-crossbred steers were used to evaluate the effects of forage species grazed in the last 41 d of the finishing period on rib composition, color, and palatability in forage-finished beef and compared to traditional high concentrate finished. Steers grazed naturalized pastures (bluegr...

  12. Fractured Ribs and the CT Funky Fat Sign of Diaphragmatic Rupture

    PubMed Central

    Strollo, Diane C.

    2016-01-01

    Traumatic diaphragmatic rupture remains a diagnostic challenge for both radiologists and surgeons. In recent years, multidetector CT has markedly improved the diagnosis of diaphragmatic injury in polytrauma patients. Herein, we describe two cases of subacute presentation of traumatic diaphragmatic rupture from a penetrating rib fracture and subsequent intrathoracic herniation of omental fat, representing the CT “funky fat” sign. PMID:27429823

  13. Partitioning of the contributions of rib cage and abdomen to ventilation in ankylosing spondylitis

    PubMed Central

    Grimby, Gunnar; Fugl-Meyer, Axel R.; Blomstrand, Ann

    1974-01-01

    Grimby, G., Fugl-Meyer, A. R., and Blomstrand, A. (1974).Thorax,29, 179-184. Partitioning of the contributions of rib cage and abdomen to ventilation in ankylosing spondylitis. The relative contributions of the rib cage and abdomen to ventilation were studied in the sitting position in patients with ankylosing spondylitis, using measurements of changes in the anteroposterior diameters. The functional impairment of the spine and adjacent joints was also evaluated. In most patients vital capacity and total lung capacity were reduced, but functional residual capacity was normal. The relative contribution of the rib cage to ventilation was reduced at rest compared to normal subjects, and decreased further during hyperventilation induced by rebreathing. The end-expiratory level of the abdomen decreased more markedly during hyperventilation than in normal subjects and even the end-inspiratory level of the abdomen increased somewhat. The findings are consistent with a reduced mobility of the ribs and a greater than normal excursion of the diaphragm during breathing. PMID:4831523

  14. Enhanced heat transfer in ribbed ducts using vortex generators. Annual report, July 1991-June 1992

    SciTech Connect

    Myrum, T.A.; Acharya, S.

    1992-08-10

    Local and average Nusselt number and overall pressure drop results were obtained experimentally for an air flow (Re = 3450) in a ribbed duct with vortex generators (circular rods) placed immediately above or just downstream of select rib elements. In virtually all cases, the presence of the generators led to increases in the average Nusselt number, Nu, and decreases in the entropy generation per unit duct length, S'. The largest generator-induced enhancement occurred for the largest dimensionless rib pitch (P/h = 38.4), where placing the largest diameter generators (d/h = 1.0) over every rib produced a 21-percent increase in Nu, and a 27-percent decrease in S'. For P/h = 19.2, the best performance corresponded to a 12-percent increase in Nu and a 9-percent decrease in S'. The local results demonstrated that the greatest generator-induced effect occurred behind the first generator, located at the entrance to the test section. Downstream, the generators typically had a minor impact on the local Nusselt number and frequently reduced the local Nusselt number.

  15. Rib Torque Does Not Assist Resting Tidal Expiration or Most Conversational Speech Expiration

    ERIC Educational Resources Information Center

    Hixon, Thomas J.

    2006-01-01

    Purpose: This research note discusses a common misconception in speech science and speech-language pathology textbooks that rib torque (i.e., "rotational stress") assists resting tidal expiration and conversational speech production. Method: The nature of this misconception is considered. Conclusion: An alternate conceptualization is offered that…

  16. Accuracy and sampling error of two age estimation techniques using rib histomorphometry on a modern sample.

    PubMed

    García-Donas, Julieta G; Dyke, Jeffrey; Paine, Robert R; Nathena, Despoina; Kranioti, Elena F

    2016-02-01

    Most age estimation methods are proven problematic when applied in highly fragmented skeletal remains. Rib histomorphometry is advantageous in such cases; yet it is vital to test and revise existing techniques particularly when used in legal settings (Crowder and Rosella, 2007). This study tested Stout & Paine (1992) and Stout et al. (1994) histological age estimation methods on a Modern Greek sample using different sampling sites. Six left 4th ribs of known age and sex were selected from a modern skeletal collection. Each rib was cut into three equal segments. Two thin sections were acquired from each segment. A total of 36 thin sections were prepared and analysed. Four variables (cortical area, intact and fragmented osteon density and osteon population density) were calculated for each section and age was estimated according to Stout & Paine (1992) and Stout et al. (1994). The results showed that both methods produced a systemic underestimation of the individuals (to a maximum of 43 years) although a general improvement in accuracy levels was observed when applying the Stout et al. (1994) formula. There is an increase of error rates with increasing age with the oldest individual showing extreme differences between real age and estimated age. Comparison of the different sampling sites showed small differences between the estimated ages suggesting that any fragment of the rib could be used without introducing significant error. Yet, a larger sample should be used to confirm these results. PMID:26698389

  17. Shape optimization of staggered ribs in a rotating equilateral triangular cooling channel

    NASA Astrophysics Data System (ADS)

    Moon, Mi-Ae; Park, Min-Jung; Kim, Kwang-Yong

    2014-04-01

    A rotating equilateral triangular cooling channel with staggered square ribs inside the leading edge of a turbine blade has been optimized in this work based on surrogate modeling. The fluid flow and heat transfer in the channel have been analyzed using three-dimensional Reynolds-averaged Navier-Stokes (RANS) equations under uniform heat flux condition. Shear stress transport turbulence model has been used as a turbulence closure. Computational results for area-averaged Nusselt number have been validated compared to the experimental data. The objectives related to the heat transfer rate and pressure drop has been linearly combined with a weighting factor to define the objective function. The angle of the rib, the rib pitch-to-hydraulic diameter ratio, and the rib width-to-hydraulic diameter ratio have been selected as the design variables. Twenty-two design points have been generated by Latin Hypercube sampling, and the values of the objective function have been calculated by the RANS analysis at these points. The surrogate model for the objective function has been constructed using the radial basis neural network method. Through the optimization, the objective function value has been improved by 21.5 % compared to that of the reference geometry.

  18. SUPERNUMERARY RIBS IN DEVELOPMENTAL TOXICITY BIOASSAYS AND IN HUMAN POPULATIONS: INCIDENCE AND BIOLOGICAL SIGNIFICANCE

    EPA Science Inventory

    Abstract
    Supernumerary or accessory ribs (SNR), either lumbar (LSNR) or cervical (CSNR) are a common finding in standard developmental toxicology bioassays. The biological significance of these anomalies within the regulatory arena has been problematic and the subject of some...

  19. Ovariectomy-induced changes in aged beagles: Histomorphometry and mineral content of the rib

    SciTech Connect

    Wilson, A.K.; Bhattacharyya, M.H.; Hurst, D.; Miller, S.; Sacco-Gibson, N.

    1997-08-01

    The effects of ovariectomy on the aged beagle skeleton were studied by histomorphometric analysis of the cortical bone in sequential rib biopsies. Biopsies were taken from each ovariectomized (OV) or sham-operated (SO) dog at the time of surgery and at 1, 4, and 8.5 months after surgery. Tetracycline, calcein, and xylenol orange, respectively, were administered by a fluorochrome labeling procedure (2d-10d-2d) just prior to each postoperative biopsy to provide markers of bone formation. Analysis of sequential biopsies provided a means to follow the response to ovariectomy over time and compare each animal against its own baseline. Examination of sequential biopsies indicated that cortical porosity increased by the fourth month after ovariectomy and remained high at 8.5 months. Ovariectomy did not influence histomorphometric indices at one month after surgery, but substantial differences were observed at later times. Ovariectomy stimulated a transient increase in bone formation and was increased six-fold over that of SO dogs at four months. Ribs were also analyzed for mineral content at necropsy. The rib was heterogeneous along its length for calcium content and concentration. In the midrib where biopsies for histomorphometric analysis were taken, ovariectomy induced a decrease in mass and mineral content; total calcium was decreased by approximately 31%. These data demonstrate that the rib cortical bone is a responsive site for the effects of ovariectomy in female dogs.

  20. Effect of rib cage and abdominal restriction on total respiratory resistance and reactance.

    PubMed

    van Noord, J A; Demedts, M; Clément, J; Cauberghs, M; Van de Woestijne, K P

    1986-11-01

    In 14 healthy male subjects we studied the effects of rib cage and abdominal strapping on lung volumes, airway resistance (Raw), and total respiratory resistance (Rrs) and reactance (Xrs). Rib cage, as well as abdominal, strapping caused a significant decrease in vital capacity (respectively, -36 and -34%), total lung capacity (TLC) (-31 and -27%), functional residual capacity (FRC) (-28 and -28%), and expiratory reserve volume (-40 and -48%) and an increase in specific airway conductance (+24 and +30%) and in maximal expiratory flow at 50% of control TLC (+47 and +42%). The decrease of residual volume (RV) was significant (-12%) with rib cage strapping only. Abdominal strapping resulted in a minor overall increase in Rrs, whereas rib cage strapping produced a more marked increase at low frequencies; thus a frequency dependence of Rrs was induced. A similar pattern, but with lower absolute values, of Rrs was obtained by thoracic strapping when the subject was breathing at control FRC. Xrs was decreased, especially at low frequencies, with abdominal strapping and even more with thoracic strapping; thus the resonant frequency of the respiratory system was shifted toward higher frequencies. Partitioning Rrs and Xrs into resistance and reactance of lungs and chest wall demonstrated that the different effects of chest wall and abdominal strapping on Rrs and Xrs reflect changes mainly of chest wall mechanics. PMID:3781983

  1. The Effects of Surface Waviness and of Rib Stitching on Wing Drag

    NASA Technical Reports Server (NTRS)

    Hood, Manley J

    1939-01-01

    Surface waviness and rib stitching have been investigated as part of a series of tests to determine the effects on wing drag of common surface irregularities. The tests were made in the N.A.C.A. 8-foot high-speed wind tunnel at Reynolds Numbers up to 17,000,000. The results of the tests showed that the waviness common to airplane wings will cause no serious increase in drag unless the waviness exists on the forward part of the wing, where it may cause premature transition or premature compressibility effects. Waves 3 inches wide and 0.048 inch high, for example, increased the drag 1 percent when they covered the rear 67 percent of both surfaces and 10 percent when they covered the rear 92 percent. A single wave 3 inches wide and only 0.020 inch high at the 10.5-percent-chord point on the upper surface caused transition to occur on the wave and increased the drag 6 percent. Rib stitching increased the drag 7 percent when the rib spacing was 6 inches; the drag increment was proportional to the number of ribs for wider spacings. About one-third of the increase was due to premature transition at the forward ends of the stitching.

  2. Fractured Ribs and the CT Funky Fat Sign of Diaphragmatic Rupture.

    PubMed

    Ocak, Iclal; Strollo, Diane C

    2016-01-01

    Traumatic diaphragmatic rupture remains a diagnostic challenge for both radiologists and surgeons. In recent years, multidetector CT has markedly improved the diagnosis of diaphragmatic injury in polytrauma patients. Herein, we describe two cases of subacute presentation of traumatic diaphragmatic rupture from a penetrating rib fracture and subsequent intrathoracic herniation of omental fat, representing the CT "funky fat" sign. PMID:27429823

  3. Evolution of the respiratory system in nonavian theropods: evidence from rib and vertebral morphology.

    PubMed

    Schachner, Emma R; Lyson, Tyler R; Dodson, Peter

    2009-09-01

    Recent reports of region-specific vertebral pneumaticity in nonavian theropod dinosaurs have brought attention to the hypothesis that these animals possessed an avian-style respiratory system with flow-through ventilation. This study explores the thoracic rib and vertebral anatomy of Sinraptor, Allosaurus, Tyrannosaurus, and Deinonychus; four nonavian theropods that all show well-preserved thoracic vertebrae and ribs. Comparisons to the osteology and soft tissue anatomy of extant saurians provide new evidence supporting the hypothesis of flow-through ventilation in nonavian theropods. Analyses of diapophyseal and parapophyseal position and thoracic rib morphology suggest that most nonavian theropods possessed lungs that were deeply incised by the adjacent bicapitate thoracic ribs. This functionally constrains the lungs as rigid nonexpansive organs that were likely ventilated by accessory nonvascularized air sacs. The axial anatomy of this group also reveals that a crocodilian-like hepatic-piston lung would be functionally and biomechanically untenable. Taken together with the evidence that avian-like air sacs were present in basal theropods, these data lead us to conclude that an avian-style pulmonary system was likely a universal theropod trait. PMID:19711481

  4. Forage quality and grazing performance of beef cattle grazing brown mid-rib grain sorghum residue

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Residue from grain sorghum hybrids, one control (AWheatland x RTx430) and its near isogenic with the brown mid-rib (BMR) trait, were compared in a 72-d grazing experiment. Forty eight steers (250 ± 23 kg) were stratified by BW and assigned randomly to 2.12 ha paddocks (6 steers/paddock) containing B...

  5. 30 CFR 57.3460 - Maintenance between machinery or equipment and ribs.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Maintenance between machinery or equipment and... NONMETAL MINES Ground Control Precautions-Underground Only § 57.3460 Maintenance between machinery or equipment and ribs. Persons shall not perform maintenance work between machinery or equipment and...

  6. 13. Detail of abutment/arch rib juncture. Northeast end of bridge, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. Detail of abutment/arch rib juncture. Northeast end of bridge, looking east to west. - Presumpscot Falls Bridge, Spanning Presumptscot River at Allen Avenue extension, 0.75 mile west of U.S. Interstate 95, Falmouth, Cumberland County, ME

  7. Trauma patient adverse outcomes are independently associated with rib cage fracture burden and severity of lung, head, and abdominal injuries

    PubMed Central

    Dunham, C Michael; Hileman, Barbara M; Ransom, Kenneth J; Malik, Rema J

    2015-01-01

    Objective: We hypothesized that lung injury and rib cage fracture quantification would be associated with adverse outcomes. Subjects and methods: Consecutive admissions to a trauma center with Injury Severity Score ≥ 9, age 18-75, and blunt trauma. CT scans were reviewed to score rib and sternal fractures and lung infiltrates. Sternum and each anterior, lateral, and posterior rib fracture was scored 1 = non-displaced and 2 = displaced. Rib cage fracture score (RCFS) = total rib fracture score + sternal fracture score + thoracic spine Abbreviated Injury Score (AIS). Four lung regions (right upper/middle, right lower, left upper, and left lower lobes) were each scored for % of infiltrate: 0% = 0; ≤ 20% = 1, ≤ 50% = 2, > 50% = 3; total of 4 scores = lung infiltrate score (LIS). Results: Of 599 patients, 193 (32%) had 854 rib fractures. Rib fracture patients had more abdominal injuries (p < 0.001), hemo/pneumothorax (p < 0.001), lung infiltrates (p < 0.001), thoracic spine injuries (p = 0.001), sternal fractures (p = 0.0028) and death or need for mechanical ventilation ≥ 3 days (Death/Vdays ≥ 3) (p < 0.001). Death/Vdays ≥ 3 was independently associated with RCFS (p < 0.001), LIS (p < 0.001), head AIS (p < 0.001) and abdominal AIS (p < 0.001). Of the 193 rib fracture patients, Glasgow Coma Score 3-12 or head AIS ≥ 2 occurred in 43%. A lung infiltrate or hemo/pneumothorax occurred in 55%. Thoracic spine injury occurred in 23%. RCFS was 6.3 ± 4.4 and Death/Vdays ≥ 3 occurred in 31%. Death/Vdays ≥ 3 rates correlated with RCFS values: 19% for 1-3; 24% for 4-6; 42% for 7-12 and 65% for ≥ 13 (p < 0.001). Death/Vdays ≥ 3 was independently associated with RCFS (p = 0.02), LIS (p = 0.001), head AIS (p < 0.001) and abdominal AIS (p < 0.001). Death/Vdays ≥ 3 association was better for RCFS (p = 0.005) than rib fracture score (p = 0.08) or number of fractured ribs (p = 0.80). Conclusion: Rib fracture patients have increased risk for truncal injuries and

  8. HIFU scattering by the ribs: constrained optimisation with a complex surface impedance boundary condition

    NASA Astrophysics Data System (ADS)

    Gélat, P.; ter Haar, G.; Saffari, N.

    2014-04-01

    High intensity focused ultrasound (HIFU) enables highly localised, non-invasive tissue ablation and its efficacy has been demonstrated in the treatment of a range of cancers, including those of the kidney, prostate and breast. HIFU offers the ability to treat deep-seated tumours locally, and potentially bears fewer side effects than more established treatment modalities such as resection, chemotherapy and ionising radiation. There remains however a number of significant challenges which currently hinder its widespread clinical application. One of these challenges is the need to transmit sufficient energy through the ribcage to ablate tissue at the required foci whilst minimising the formation of side lobes and sparing healthy tissue. Ribs both absorb and reflect ultrasound strongly. This sometimes results in overheating of bone and overlying tissue during treatment, leading to skin burns. Successful treatment of a patient with tumours in the upper abdomen therefore requires a thorough understanding of the way acoustic and thermal energy is deposited. Previously, a boundary element (BE) approach based on a Generalised Minimal Residual (GMRES) implementation of the Burton-Miller formulation was developed to predict the field of a multi-element HIFU array scattered by human ribs, the topology of which was obtained from CT scan data [1]. Dissipative mechanisms inside the propagating medium have since been implemented, together with a complex surface impedance condition at the surface of the ribs. A reformulation of the boundary element equations as a constrained optimisation problem was carried out to determine the complex surface velocities of a multi-element HIFU array which generated the acoustic pressure field that best fitted a required acoustic pressure distribution in a least-squares sense. This was done whilst ensuring that an acoustic dose rate parameter at the surface of the ribs was kept below a specified threshold. The methodology was tested at an

  9. Modelling of the acoustic field of a multi-element HIFU array scattered by human ribs

    NASA Astrophysics Data System (ADS)

    Gélat, Pierre; ter Haar, Gail; Saffari, Nader

    2011-09-01

    The efficacy of high-intensity focused ultrasound (HIFU) for the treatment of a range of different cancers, including those of the liver, prostate and breast, has been demonstrated. As a non-invasive focused therapy, HIFU offers considerable advantages over techniques such as chemotherapy and surgical resection in terms of reduced risk of harmful side effects. Despite this, there are a number of significant challenges which currently hinder its widespread clinical application. One of these challenges is the need to transmit sufficient energy through the rib cage to induce tissue necrosis in the required volume whilst minimizing the formation of side lobes. Multi-element random-phased arrays are currently showing great promise in overcoming the limitations of single-element transducers. Nevertheless, successful treatment of a patient with liver tumours requires a thorough understanding of the way in which the ultrasonic pressure field from a HIFU array is scattered by the rib cage. In order to address this, a boundary element approach based on a generalized minimal residual (GMRES) implementation of the Burton-Miller formulation was used in conjunction with phase conjugation techniques to focus the field of a 256-element random HIFU array behind human ribs at locations requiring intercostal and transcostal treatment. Simulations were carried out on a 3D mesh of quadratic pressure patches generated using CT scan anatomical data for adult ribs 9-12 on the right side. The methodology was validated on spherical and cylindrical scatterers. Field calculations were also carried out for idealized ribs, consisting of arrays of strip-like scatterers, demonstrating effects of splitting at the focus. This method has the advantage of fully accounting for the effect of scattering and diffraction in 3D under continuous wave excitation.

  10. Data Qualification Report For DTN: MO0012RIB00065.002, Parameter Values For Transfer Coefficients

    SciTech Connect

    C.H. Tung

    2001-01-09

    A data-qualification evaluation was conducted on Reference Information Base (RIB) data set MOO0 12RIB00065.002, ''Parameter Values for Transfer Coefficients''. The corroborating data method was used to evaluate the data. This method was selected because it closely matches the literature-review method followed to select parameter values. Five criteria were considered when the corroborating method was used: adequacy of the corroborative literature, sufficiency of value-selection criteria, implementation of the selection criteria, documentation of the process, and whether the analysis was conducted in accordance with applicable quality assurance (QA) procedures. Three criteria were used when a literature review was not conducted: appropriate logic used to select parameters, documentation of the process, and whether the analysis was conducted in accordance with applicable QA procedures. The RIB data item, the associated Analysis and Model Report (AMR), the corroborative literature, and the results of an audit revision O/ICN 0 of the AMR were examined. All calculations and the selection process for all values were repeated and confirmed. The qualification team concluded: (1) A sufficient quantity of corroborative literature was reviewed and no additional literature was identified that should have been considered. (2) The selection criteria were sufficient and resulted in valid parameter values. (3) The process was well defined, adequately documented in the AMR, and correctly followed. (4) The analysis was developed in accordance with applicable QA procedures. No negative findings were documented that resulted in questions about the quality of the data. The qualification team therefore recommends that the qualification status of RIB data set MO0012RIB00065.002 be changed to qualified.

  11. Numerical simulations of heat transfer distribution of a two-pass square channel with V-rib turbulator and bleed holes

    NASA Astrophysics Data System (ADS)

    Kumar, Sourabh; Amano, R. S.; Lucci, Jose Martinez

    2013-08-01

    The blade tip region in gas turbine encounters high thermal loads due to temperature difference and hence efforts for high durability and safe operations are essential. Improved and robust methods of cooling are required to downgrade heat transfer rate to turbine blades. The blade tip regions, which are exposed to high gas flow, suffers high local thermal load which are due to external tip leakage. Jet impingement, pin cooling etc. are techniques used for cooling blades. A more usual way is to use serpentine passage with 180-degree turn. In this study, numerical simulation of heat transfer distribution of a two-pass square channel with rib turbulators and bleed holes were done. Periodical rib turbulators and bleed holes were used in the channel. The ribs arrangement were 60 degree V rib, 60 degree inverted V ribs, combination of 60 degree V rib at inlet and 60 inverted V rib at outlet section and combination of Inverted V at inlet and V rib at the outlet. The results were numerically computed using Fluent with Reynolds number of 12,500 and 28,500. Turbulence models used for computations were k-ω-SST and RSM. Temperature based and shear stress based techniques were used for heat transfer distribution prediction. The results for 60 degree V rib, 60 degree inverted V ribs were compared with the experimental results for validation of the results obtained. Detailed distribution shows distinctive peaks in heat transfer around bleed holes and rib turbulator. Comparisons of the overall performance of the models with different orientation of rib turbulator are presented. It is found that due to the combination of 60 degree inverted V rib in inlet and 60 V rib in outlet with bleed holes provides better heat treatment. It is suggested that the use of rib turbulator with bleed holes provides suitable for augmenting blade cooling to achieve an optimal balance between thermal and mechanical design requirements.

  12. Heat transfer in a two-pass internally ribbed turbine blade coolant channel with cylindrical vortex generators

    SciTech Connect

    Hibbs, R.G.; Acharya, S.; Chen, Y.; Nikitopoulos, D.E.; Myrum, T.A.

    1998-07-01

    The effect of vortex generators on the mass (heat) transfer from the ribbed passage of a two-pass turbine blade coolant channel is investigated with the intent of optimizing the vortex generator geometry so that significant enhancements in mass/heat transfer can be achieved. In the experimental configuration considered, ribs are mounted on two opposite walls; all four walls along each pass are active and have mass transfer from their surfaces but the ribs are nonparticipating. Mass transfer measurements, in the form of Sherwood number ratios, are made along the centerline and in selected interrib modules. Results are presented for Reynolds number in the range of 5000 to 40,000 pitch to rib height ratios of 10.5 and 21, and vortex generator-rib spacing to rib height ratios of 0.55 and 1.5. Centerline and spanwise-averaged Sherwood number ratios are presented along with contours of the Sherwood number ratios. Results indicate that the vortex generators lead to substantial increases in the local mass transfer rates, particularly along the side walls, and modest increases in the average mass transfer rates. The vortex generators have the effect of making the interrib profiles along the ribbed walls more uniform. Along the side walls, vortices that characterize the vortex generator wake are associated with significant mass transfer enhancements. The wake effects and the levels of enhancement decrease somewhat with increasing Reynolds number and decreasing pitch.

  13. The rib1 Mutant Is Resistant to Indole-3-Butyric Acid, an Endogenous Auxin in Arabidopsis1

    PubMed Central

    Poupart, Julie; Waddell, Candace S.

    2000-01-01

    The presence of indole-3-butyric acid (IBA) as an endogenous auxin in Arabidopsis has been recently demonstrated. However, the in vivo role of IBA remains to be elucidated. We present the characterization of a semi-dominant mutant that is affected in its response to IBA, but shows a wild-type response to indole-3-acetic acid (IAA), the predominant and most studied form of auxin. We have named this mutant rib1 for resistant to IBA. Root elongation assays show that rib1 is specifically resistant to IBA, to the synthetic auxin 2,4-dichlorophenoxyacetic acid, and to auxin transport inhibitors. rib1 does not display increased resistance to IAA, to the synthetic auxin naphthalene acetic acid, or to other classes of plant hormones. rib1 individuals also have other root specific phenotypes including a shortened primary root, an increased number of lateral roots, and a more variable response than wild type to a change in gravitational vector. Adult rib1 plants are morphologically indistinguishable from wild-type plants. These phenotypes suggest that rib1 alters IBA activity in the root, thereby affecting root development and response to environmental stimuli. We propose models in which RIB1 has a function in either IBA transport or response. Our experiments also suggest that IBA does not use the same mechanism to exit cells as does IAA and we propose a model for IBA transport. PMID:11115890

  14. Shaping frequency response of a vibrating plate for passive and active control applications by simultaneous optimization of arrangement of additional masses and ribs. Part I: Modeling

    NASA Astrophysics Data System (ADS)

    Wrona, Stanislaw; Pawelczyk, Marek

    2016-03-01

    An ability to shape frequency response of a vibrating plate according to precisely defined demands has a very high practical potential. It can be applied to improve acoustic radiation of the plate for required frequencies or enhance acoustic isolation of noise barriers and device casings by using both passive and active control. The proposed method is based on mounting severaladditional ribs and masses (passive and/or active) to the plate surface at locations followed from an optimization process. This paper, Part I, concerns derivation of a mathematical model of the plate with attached elements in the function of their shape and placement. The model is validated by means of simulations and laboratory experiments, and compared with models known from the literature. This paper is followed by a companion paper, Part II, where the optimization process is described. It includes arrangement of passive elements as well as actuators and sensors to improve controllability and observability measures, if active control is concerned.

  15. Plans for Constructing a Next-Generation ISOL Facility at ORNL

    SciTech Connect

    Garrett, J.D.

    1998-10-05

    The U.S. Nuclear Science Community in its 1996 Long Range Plan identified an advanced radioactive ion beam (RIB) facility based on the ISOL technique as the next major facility to be constructed for U.S. nuclear physics. The proposed SpaHation Neutron Source (SNS) for Oak Ridge National Laboratory, whose construction design funds have recently been appropriated, offers a unique opportunity for the construction of this new facility, Plans for extracting a proton beam from the SNS, transporting it to the RIB facility, and constructing the new RIB facility at the SNS site are discussed, as are the ISOL targets, radiation handling, isobaric separation, acceleration of beams of radioactive experimental areas.

  16. Flutter of a sandwich cylindrical shell supported with annular ribs and loaded with axial forces

    NASA Astrophysics Data System (ADS)

    Bakulin, V. N.; Volkov, E. N.; Nedbaj, A. Ya.

    2015-08-01

    The supersonic flutter of a sandwich cylindrical shell supported from within with annular ribs and loaded with axial forces on the end faces is investigated. The shell motion is described by the equations of the theory of sandwich orthotropic shells. The solution of the equations is sought as a trigonometric series with respect to the axial coordinate. With the help of the Bubnov—Galerkin method, this problem is reduced to the set of algebraic equations for the analysis of the stability of which one uses the Routh—Hurwits criterion. By a numerical example, the effect of the number and the heights of the ribs on the critical velocity of the flow around the shell is shown.

  17. A Rare Case of Dacron Graft Rupture due to Friction against a Rib.

    PubMed

    Matsuyama, Katsuhiko; Kuinose, Masahiko; Koizumi, Nobusato; Iwahashi, Toru; Toguchi, Kayo; Ogino, Hitoshi

    2014-12-01

    A 54-year-old man underwent aortic repair for the infected thoracoabdominal aneurysm with a woven Dacron graft (Vascutek, Renfrewshire, Scotland) treated with gentian violet. Four months later, he complained of sudden back pain, resulting in preshock status. Computed tomographic scans showed massive hematoma around the Dacron graft, suggesting graft rupture. Initially, emergency thoracic endovascular aortic repair was performed, which was subsequently followed by open repair. The Dacron graft had a small hole, which was completely compatible with the site contacting with the rib. The graft rupture was considered due to its friction against the rib. We report on a rare event of mechanical Dacron graft rupture after the thoracoabdominal aortic replacement. PMID:25798369

  18. Heat transfer measurements to a gas turbine cooling passage with inclined ribs

    SciTech Connect

    Wang, Z.; Ireland, P.T.; Kohler, S.T.; Chew, J.W.

    1998-01-01

    The local heat transfer coefficient distribution over all four walls of a large-scale model of a gas turbine cooling passage have been measured in great detail. A new method of determining the heat transfer coefficient to the rib surface has been developed and the contribution of the rib, at 5% blockage, to the overall roughened heat transfer coefficient was found to be considerable. The vortex-dominated flow field was interpreted from the detailed form of the measured local heat transfer contours. Computational Fluid Dynamics calculations support this model of the flow and yield friction factors that agree with measured values. Advances in the heat transfer measuring technique and data analysis procedure that confirm the accuracy of the transient method are described in full.

  19. Nose and Midface Augmentation by Rib Cartilage Grafts: Methods and Outcome in 32 Cases

    PubMed Central

    Ibrahiem, Saad

    2015-01-01

    Recession of the midface is a relatively common condition that can have a negative impact on facial and nasal aesthetic appearance, and it poses a challenge to plastic surgeons. In cases with generalized maxillary retrusion and/or malocclusion, bone advancement surgery is required, but in localized cases, mostly seen in cleft lip patients, the quest is for an ideal material and a proper technique that would be used to augment the receding area. Throughout a period of seven years, thirty-two patients with nose and midface retrusion were managed by a construct of rib cartilage grafts designed to compensate the deficiency at the maxillary, piriform, and premaxillary areas. Results were satisfactory for most patients in terms of improved fullness of malar area, improved nasal tip projection and rotation, and improvement of upper lip. The presented technique of rib cartilage grafting is a safe and effective method for nose and midface augmentation. PMID:26858843

  20. Ultrasound image segmentation with shape priors: application to automatic cattle rib-eye area estimation.

    PubMed

    Arias, Pablo; Pini, Alejandro; Sanguinetti, Gonzalo; Sprechmann, Pablo; Cancela, Pablo; Fernández, Alicia; Gómez, Alvaro; Randall, Gregory

    2007-06-01

    Automatic ultrasound (US) image segmentation is a difficult task due to the quantity of noise present in the images and the lack of information in several zones produced by the acquisition conditions. In this paper, we propose a method that combines shape priors and image information to achieve this task. In particular, we introduce knowledge about the rib-eye shape using a set of images manually segmented by experts. A method is proposed for the automatic segmentation of new samples in which a closed curve is fitted taking into account both the US image information and the geodesic distance between the evolving curve and the estimated mean rib-eye shape in a shape space. This method can be used to solve similar problems that arise when dealing with US images in other fields. The method was successfully tested over a database composed of 610 US images, for which we have the manual segmentations of two experts. PMID:17547141

  1. A Rare Case of Dacron Graft Rupture due to Friction against a Rib

    PubMed Central

    Matsuyama, Katsuhiko; Kuinose, Masahiko; Koizumi, Nobusato; Iwahashi, Toru; Toguchi, Kayo; Ogino, Hitoshi

    2014-01-01

    A 54-year-old man underwent aortic repair for the infected thoracoabdominal aneurysm with a woven Dacron graft (Vascutek, Renfrewshire, Scotland) treated with gentian violet. Four months later, he complained of sudden back pain, resulting in preshock status. Computed tomographic scans showed massive hematoma around the Dacron graft, suggesting graft rupture. Initially, emergency thoracic endovascular aortic repair was performed, which was subsequently followed by open repair. The Dacron graft had a small hole, which was completely compatible with the site contacting with the rib. The graft rupture was considered due to its friction against the rib. We report on a rare event of mechanical Dacron graft rupture after the thoracoabdominal aortic replacement. PMID:25798369

  2. Sound absorption of a rib-stiffened plate covered by anechoic coatings.

    PubMed

    Fu, Xinyi; Jin, Zhongkun; Yin, Yao; Liu, Bilong

    2015-03-01

    Underwater vehicles are often equipped with anechoic coatings to absorb the sound waves of active sonar and attenuate the noise emitted from the vessels. Rubber layers with periodically distributed air cavities are widely used as anechoic coatings. In this paper, the sound absorption of anechoic coatings embedded with doubly periodic cavities and backed with periodically rib-stiffened plates is investigated using a finite element method (FEM) with Bloch-periodic boundary conditions. Numerical results given by the FEM are compared with those of a simplified transfer impedance approach to explain the shifting of the main absorption peak. Further a simplified FEM approach, which reduces calculation time significantly and maintains the reasonable accuracy, is proposed for a comparison. The results indicate that the plate and the ribs can have significant impacts on the absorption performance of anechoic coatings, especially at low frequencies. PMID:25786965

  3. Recent results from the TwinSol low-energy RIB facility

    NASA Astrophysics Data System (ADS)

    Becchetti, F. D.; Kolata, J. J.

    2016-06-01

    We report on some of the recent developments and experimental work done at the twin-solenoid low-energy radioactive-ion-beam (RIB) facility TwinSol installed at the U Notre Dame 10 MV FN tandem accelerator. The TwinSol facility is a joint project of the University of Michigan (UM) and the University of Notre Dame (UND), and includes several U.S. and foreign collaborators. A number of significant experiments including RIB-induced transfer reactions, elastic scattering, resonant scattering, and fusion at energies near and well below the Coulomb barrier have been performed with this facility. Several of these as well as future work and upgrades planned will be described.

  4. Dynamic Stability of a Cylindrical Shell Reinforced by Longitudinal Ribs and a Hollow Cylinder Under the Action of Axial Forces

    NASA Astrophysics Data System (ADS)

    Bakulin, V. N.; Volkov, E. N.; Nedbai, A. Ya.

    2016-06-01

    The dynamic stability of a cylindrical orthotropic shell reinforced by longitudinal ribs and a hollow cylinder under the action of axial forces changing harmonically with time was investigated with regard for the axial contact interaction of the shell with the ribs. A solution of the differential equations defining this process has been obtained in the form of trigonometric series in the angular and time coordinates. A two-term approximation of the Mathieu-Hill equations of motion was used for construction of the main region of instability of the shell. As a result, the problem was reduced to a system of algebraic equations for components of displacements of the shell at the locations of the ribs. The problem for uniformly spaced ribs was solved in the explicit form. A numerical example of this solution is presented.

  5. Dynamic Stability of a Cylindrical Shell Reinforced by Longitudinal Ribs and a Hollow Cylinder Under the Action of Axial Forces

    NASA Astrophysics Data System (ADS)

    Bakulin, V. N.; Volkov, E. N.; Nedbai, A. Ya.

    2016-05-01

    The dynamic stability of a cylindrical orthotropic shell reinforced by longitudinal ribs and a hollow cylinder under the action of axial forces changing harmonically with time was investigated with regard for the axial contact interaction of the shell with the ribs. A solution of the differential equations defining this process has been obtained in the form of trigonometric series in the angular and time coordinates. A two-term approximation of the Mathieu-Hill equations of motion was used for construction of the main region of instability of the shell. As a result, the problem was reduced to a system of algebraic equations for components of displacements of the shell at the locations of the ribs. The problem for uniformly spaced ribs was solved in the explicit form. A numerical example of this solution is presented.

  6. Technical note: Prediction of chemical rib section composition by dual energy X-ray absorptiometry in Zebu beef cattle.

    PubMed

    Prados, L F; Zanetti, D; Amaral, P M; Mariz, L D S; Sathler, D F T; Filho, S C Valadares; Silva, F F; Silva, B C; Pacheco, M C; Alhadas, H M; Chizzotti, M L

    2016-06-01

    It is expensive and laborious to evaluate carcass composition in beef cattle. The objective of this study was to evaluate a method to predict the 9th to 11th rib section (rib) composition through empirical equations using dual energy X-ray absorptiometry (DXA). Dual energy X-ray absorptiometry is a validated method used to describe tissue composition in humans and other animals, but few studies have evaluated this technique in beef cattle, and especially in the Zebu genotype. A total of 116 rib were used to evaluate published prediction equations for rib composition and to develop new regression models using a cross-validation procedure. For the proposed models, 93 ribs were randomly selected to calculate the new regression equations, and 23 different ribs were randomly selected to validate the regressions. The rib from left carcasses were taken from Nellore and Nellore × Angus bulls from 3 different studies and scanned using DXA equipment (GE Healthcare, Madison, WI) in the Health Division at Universidade Federal de Viçosa (Viçosa, Brazil). The outputs of the DXA report were DXA lean (g), DXA fat free mass (g), DXA fat mass (g), and DXA bone mineral content (BMC; g). After being scanned, the rib were dissected, ground, and chemically analyzed for total ether extract (EE), CP, water, and ash content. The predictions of rib fat and protein from previous published equations were different ( < 0.01) from the observed composition. New equations were established through leave-one-out cross-validation using the REG procedure in SAS. The equations were as follows: lean (g) = 37.082 + 0.907× DXA lean ( = 0.95); fat free mass (g) = 103.224 + 0.869 × DXA fat free mass ( = 0.93); EE mass (g) = 122.404 + 1.119 × DXA fat mass ( = 0.86); and ash mass (g) = 18.722 + 1.016 × DXA BMC ( = 0.39). The equations were validated using Mayer's test, the concordance correlation coefficient, and the mean square error of prediction for decomposition. For both equations, Mayer's test

  7. Improving detector spatial resolution using pixelated scintillators with a barrier rib structure

    NASA Astrophysics Data System (ADS)

    Liu, Langechuan; Lu, Minghui; Cao, Wanqing; Peng, Luke; Chen, Arthur

    2016-03-01

    Indirect conversion flat panel detectors (FPDs) based on amorphous silicon (a-Si) technology are widely used in digital X-ray imaging. In such FPDs a scintillator layer is used for converting X-rays into visible light photons. However, the lateral spread of these photons inside the scintillator layer reduces spatial resolution of the FPD. In this study, FPDs incorporating pixelated scintillators with a barrier rib structure were developed to limit lateral spread of light photons thereby improving spatial resolution. For the pixelated scintillator, a two-dimensional barrier rib structure was first manufactured on a substrate layer, coated with reflective materials, and filled to the rim with the scintillating material of gadolinium oxysulfide (GOS). Several scintillator samples were fabricated, with pitch size varying from 160 to 280 μm and rib height from 200 to 280 μm. The samples were directly coupled to an a-Si flat panel photodiode array with a pitch of 200 μm to convert optical photons to electronic signals. With the pixelated scintillator, the detector modulation transfer function was shown to improve significantly (by 94% at 2 cycle/mm) compared to a detector using an unstructured GOS layer. However, the prototype does show lower sensitivity due to the decrease in scintillator fill factor. The preliminary results demonstrated the feasibility of using the barrier-rib structure to improve the spatial resolution of FPDs. Such an improvement would greatly benefit nondestructive testing applications where the spatial resolution is the most important parameter. Further investigation will focus on improving the detector sensitivity and exploring its medical applications.

  8. Spontaneous intercostal lung herniation complicated by rib fractures: a therapeutic dilemma.

    PubMed

    Wani, Adil S; Kalamkar, Prachi; Alhassan, Sulaiman; Farrell, Michael J

    2015-12-01

    Lung herniation has been defined as a protrusion of lung tissue through its bounding structure. We present a case of spontaneous intercostal lung herniation following bouts of cough, which was complicated by multiple rib fractures, in which we had to adopt a non-surgical approach due to the clinical circumstance. Its understanding in the field of internal medicine is important as appropriate therapeutic judgment, and long-term follow-up is essential for full recovery. PMID:26719812

  9. Displacement Patterns of Blunt Rib Fractures and Their Relationship to Thoracic Coinjuries: Minimal Displacements Count.

    PubMed

    Bugaev, Nikolay; Breeze, Janis L; Alhazmi, Majid; Anbari, Hassan S; Arabian, Sandra S; Rabinovici, Reuven

    2016-03-01

    Displacement patterns of rib fractures (RF) and their association with thoracic coinjuries and outcomes are unknown. This is a retrospective review of adult patients with blunt closed RF who underwent chest CT at a Level I trauma center (2007-2012). Displacement patterns of RF were compared among the three-dimensional planes using CT images. An analysis of receiver operating characteristic (ROC) curves was performed to identify displacements in each plane most strongly associated with chest coinjuries. Univariate analysis was used to find association of displaced RF with hospital course and outcome. There were 1127 RF (245 patients, most in ribs 3-9, 45 per cent displaced). Axial displacement was the most common, with odds ratios 7.20 and 2.13 compared with cranio-caudal, and impaction-separation (along rib axis) movement, respectively. Axial displacement thresholds performed well with hemothorax (2.8 mm, ROC = 0.74), pneumothorax (2.6 mm, ROC = 0.70), hemopneumothorax (3.1 mm, ROC = 0.77), flail chest (3.4 mm, ROC = 0.80), and chest tube placement (2.8 mm, ROC = 0.75). RF displacement was associated with increased days on mechanical ventilation and hospital length of stay. In conclusion, even minimal RF displacement is associated with increased risk of chest coinjuries and chest tube placement, and displacements correlated with increased days on mechanical ventilation and hospital length of stay. Future studies are required to investigate these associations, especially in relationship to the indications for rib plating. PMID:27099054

  10. Approximate calculation of multispar cantilever and semicantilever wings with parallel ribs under direct and indirect loading

    NASA Technical Reports Server (NTRS)

    Sanger, Eugen

    1932-01-01

    A method is presented for approximate static calculation, which is based on the customary assumption of rigid ribs, while taking into account the systematic errors in the calculation results due to this arbitrary assumption. The procedure is given in greater detail for semicantilever and cantilever wings with polygonal spar plan form and for wings under direct loading only. The last example illustrates the advantages of the use of influence lines for such wing structures and their practical interpretation.

  11. Turbulent flow in rib-roughened channel under the effect of Coriolis and rotational buoyancy forces

    NASA Astrophysics Data System (ADS)

    Coletti, Filippo; Jacono, David Lo; Cresci, Irene; Arts, Tony

    2014-04-01

    The turbulent flow inside a rotating channel provided with transverse ribs along one wall is studied by means of two-dimensional time-resolved particle image velocimetry. The measurement set-up is mounted on the same rotating disk with the test section, allowing to obtain the same accuracy and resolution as in a non-rotating rig. The Reynolds number is 15 000, and the rotation number is 0.38. As the ribbed wall is heated, both the Coriolis force and the centrifugal force play a role in the fluid dynamics. The mean velocity fields highlight the major impact of the rotational buoyancy (characterized by a buoyancy number of 0.31) on the flow along the leading side of the duct. In particular, since the flow is directed radially outward, the near-wall layers experience significant centripetal buoyancy. The recirculation area behind the obstacles is enlarged to the point of spanning the whole inter-rib space. Also the turbulent fluctuations are significantly altered, and overall augmented, with respect to the non-buoyant case, resulting in higher turbulence levels far from the rib. On the other hand the centrifugal force has little or no impact on the flow along the trailing wall. Vortex identification, proper orthogonal decomposition, and two-point correlations are used to highlight rotational effects, and in particular to determine the dominant scales of the turbulent unsteady flow, the time-dependent behavior of the shear layer and of the recirculation bubble behind the wall-mounted obstacles, the lifetime and advection velocity of the coherent structures.

  12. Transmission loss of orthogonally rib-stiffened double-panel structures with cavity absorption.

    PubMed

    Xin, F X; Lu, T J

    2011-04-01

    The transmission loss of sound through infinite orthogonally rib-stiffened double-panel structures having cavity-filling fibrous sound absorptive materials is theoretically investigated. The propagation of sound across the fibrous material is characterized using an equivalent fluid model, and the motions of the rib-stiffeners are described by including all possible vibrations, i.e., flexural displacements, bending, and torsional rotations. The effects of fluid-structure coupling are account for by enforcing velocity continuity conditions at fluid-panel interfaces. By taking full advantage of the periodic nature of the double-panel, the space-harmonic approach and virtual work principle are applied to solve the sets of resultant governing equations, which are eventually truncated as a finite system of simultaneous algebraic equations and numerically solved insofar as the solution converges. To validate the proposed model, a comparison between the present model predictions and existing numerical and experimental results for a simplified version of the double-panel structure is carried out, with overall agreement achieved. The model is subsequently employed to explore the influence of the fluid-structure coupling between fluid in the cavity and the two panels on sound transmission across the orthogonally rib-stiffened double-panel structure. Obtained results demonstrate that this fluid-structure coupling affects significantly sound transmission loss (STL) at low frequencies and cannot be ignored when the rib-stiffeners are sparsely distributed. As a highlight of this research, an integrated optimal algorithm toward lightweight, high-stiffness and superior sound insulation capability is proposed, based on which a preliminary optimal design of the double-panel structure is performed. PMID:21476648

  13. Mechanical analysis of the human cadaveric thoracic spine with intact rib cage.

    PubMed

    Mannen, Erin M; Anderson, John T; Arnold, Paul M; Friis, Elizabeth A

    2015-07-16

    The goal of this study was to characterize the overall in-plane and basic coupled motion of a cadaveric human thoracic spine with intact true ribs. Researchers are becoming increasingly interested in the thoracic spine due to both the high prevalence of injury and pain in the region and also innovative surgical techniques that utilize the rib cage. Computational models can be useful tools to predict loading patterns and understand effects of surgical procedures or medical devices, but they are often limited by insufficient cadaveric input data. In this study, pure moments to ±5 Nm were applied in flexion-extension, lateral bending, and axial rotation to seven human cadaveric thoracic spine specimens (T1-T12) with intact true ribs to determine symmetry of in-plane motion, differences in neutral and elastic zone motion and stiffness, and significance of out-of-plane rotations and translations. Results showed that lateral bending and axial rotation exhibited symmetric motion, neutral and elastic zone motion and stiffness values were significantly different for all modes of bending (p<0.05), and out-of-plane rotations and translations were greater than zero for most rotations and translations. Overall in-plane rotations were 7.7±3.4° in flexion, 9.6±3.7° in extension, 23.3±8.4° in lateral bending, and 26.3±12.2° in axial rotation. Results of this study could provide inputs or validation comparisons for computational models. Future studies should characterize coupled motion patterns and local and regional level biomechanics of cadaveric human thoracic spines with intact true ribs. PMID:25912664

  14. Spontaneous intercostal lung herniation complicated by rib fractures: a therapeutic dilemma

    PubMed Central

    Wani, Adil S.; Kalamkar, Prachi; Alhassan, Sulaiman; Farrell, Michael J.

    2015-01-01

    Lung herniation has been defined as a protrusion of lung tissue through its bounding structure. We present a case of spontaneous intercostal lung herniation following bouts of cough, which was complicated by multiple rib fractures, in which we had to adopt a non-surgical approach due to the clinical circumstance. Its understanding in the field of internal medicine is important as appropriate therapeutic judgment, and long-term follow-up is essential for full recovery. PMID:26719812

  15. Thick target for high-power ISOL facilities

    NASA Astrophysics Data System (ADS)

    Bricault, Pierre G.

    2016-06-01

    The future frontier of the Isotope Separation On-Line (ISOL) method is to increase the intensity of the Radioactive Isotope Beams (RIB) by many orders of magnitude in order to satisfy challenging experiments such as Rn-Electric Dipole Moment, Fr-Parity Non Conservation… and in general for radiative proton-capture relevant for nuclear astrophysics processes. The most direct method to obtain higher RIB intensity is to increase the driver beam intensity. New techniques were developed such as composite targets, where the target material is deposited onto a high thermal conductive substrate allowing a better heat dissipation. Combined with high-power target using radial finned for radiative cooling, these targets are capable of dissipating up to 20 kW depending on the target material operating temperature. Another method to increase RIB intensity is the use of indirect ISOL method, where secondary particle beam (n or γ) interacts with a fissile target material. By decoupling the power deposition in the system composed of a converter and ISOL target allows for much higher primary beam power. Indirect ISOL-target method permit reach several hundred of kW to MW of driver beam power, allowing the production of intense fission products beams. This paper reviews the thick ISOL target approach for producing intense radioactive ion beams.

  16. Mach-Zehnder Interferometer Biochemical Sensor Based on Silicon-on-Insulator Rib Waveguide with Large Cross Section

    PubMed Central

    Yuan, Dengpeng; Dong, Ying; Liu, Yujin; Li, Tianjian

    2015-01-01

    A high-sensitivity Mach-Zehnder interferometer (MZI) biochemical sensing platform based on Silicon-in-insulator (SOI) rib waveguide with large cross section is proposed in this paper. Based on the analyses of the evanescent field intensity, the mode polarization and cross section dimensions of the SOI rib waveguide are optimized through finite difference method (FDM) simulation. To realize high-resolution MZI read-out configuration based on the SOI rib waveguide, medium-filled trenches are employed and their performances are simulated through two-dimensional finite-difference-time domain (2D-FDTD) method. With the fundamental EH-polarized mode of the SOI rib waveguide with a total rib height of 10 μm, an outside rib height of 5 μm and a rib width of 2.5 μm at the operating wavelength of 1550 nm, when the length of the sensitive window in the MZI configuration is 10 mm, a homogeneous sensitivity of 7296.6%/refractive index unit (RIU) is obtained. Supposing the resolutions of the photoelectric detectors connected to the output ports are 0.2%, the MZI sensor can achieve a detection limit of 2.74 × 10−6 RIU. Due to high coupling efficiency of SOI rib waveguide with large cross section with standard single-mode glass optical fiber, the proposed MZI sensing platform can be conveniently integrated with optical fiber communication systems and (opto-) electronic systems, and therefore has the potential to realize remote sensing, in situ real-time detecting, and possible applications in the internet of things. PMID:26343678

  17. Calculated Coupling Efficiency Between an Elliptical-Core Optical Fiber and a Silicon Oxynitride Rib Waveguide [Corrected Copy

    NASA Technical Reports Server (NTRS)

    Tuma, Margaret L.; Beheim, Glenn

    1995-01-01

    The effective-index method and Marcatili's technique were utilized independently to calculate the electric field profile of a rib channel waveguide. Using the electric field profile calculated from each method, the theoretical coupling efficiency between a single-mode optical fiber and a rib waveguide was calculated using the overlap integral. Perfect alignment was assumed and the coupling efficiency calculated. The coupling efficiency calculation was then repeated for a range of transverse offsets.

  18. The rib1 Mutant of Arabidopsis Has Alterations in Indole-3-Butyric Acid Transport, Hypocotyl Elongation, and Root Architecture1

    PubMed Central

    Poupart, Julie; Rashotte, Aaron M.; Muday, Gloria K.; Waddell, Candace S.

    2005-01-01

    Polar transport of the auxin indole-3-butyric acid (IBA) has recently been shown to occur in Arabidopsis (Arabidopis thaliana) seedlings, yet the physiological importance of this process has yet to be fully resolved. Here we describe the first demonstration of altered IBA transport in an Arabidopsis mutant, and show that the resistant to IBA (rib1) mutation results in alterations in growth, development, and response to exogenous auxin consistent with an important physiological role for IBA transport. Both hypocotyl and root IBA basipetal transport are decreased in rib1 and root acropetal IBA transport is increased. While indole-3-acetic acid (IAA) transport levels are not different in rib1 compared to wild type, root acropetal IAA transport is insensitive to the IAA efflux inhibitor naphthylphthalamic acid in rib1, as is the dependent physiological process of lateral root formation. These observed changes in IBA transport are accompanied by altered rib1 phenotypes. Previously, rib1 roots were shown to be less sensitive to growth inhibition by IBA, but to have a wild-type response to IAA in root elongation. rib1 is also less sensitive to IBA in stimulation of lateral root formation and in hypocotyl elongation under most, but not all, light and sucrose conditions. rib1 has wild-type responses to IAA, except under one set of conditions, low light and 1.5% sucrose, in which both hypocotyl elongation and lateral root formation show altered IAA response. Taken together, our results support a model in which endogenous IBA influences wild-type seedling morphology. Modifications in IBA distribution in seedlings affect hypocotyl and root elongation, as well as lateral root formation. PMID:16258013

  19. Cough-induced rib fracture and diaphragmatic rupture resulting in simultaneous abdominal visceral herniation into the left hemithorax and subcutaneously.

    PubMed

    Daniel, Romany; Naidu, Babu; Khalil-Marzouk, Joseph

    2008-10-01

    Violent coughing is associated with a multitude of complications including rib fractures and diaphragmatic rupture. In this report we present a case of a 70-year-old male with the rare combination of both complications resulting in herniation of bowel into the left hemithorax and subcutaneously between the separated ribs. Surgical repair was performed via a left thoracotomy, the hernia reduced and the diaphragmatic and chest wall defect repaired primarily with excellent patient recovery and relief of symptoms. PMID:18715797

  20. Mach-Zehnder Interferometer Biochemical Sensor Based on Silicon-on-Insulator Rib Waveguide with Large Cross Section.

    PubMed

    Yuan, Dengpeng; Dong, Ying; Liu, Yujin; Li, Tianjian

    2015-01-01

    A high-sensitivity Mach-Zehnder interferometer (MZI) biochemical sensing platform based on Silicon-in-insulator (SOI) rib waveguide with large cross section is proposed in this paper. Based on the analyses of the evanescent field intensity, the mode polarization and cross section dimensions of the SOI rib waveguide are optimized through finite difference method (FDM) simulation. To realize high-resolution MZI read-out configuration based on the SOI rib waveguide, medium-filled trenches are employed and their performances are simulated through two-dimensional finite-difference-time domain (2D-FDTD) method. With the fundamental EH-polarized mode of the SOI rib waveguide with a total rib height of 10 μm, an outside rib height of 5 μm and a rib width of 2.5 μm at the operating wavelength of 1550 nm, when the length of the sensitive window in the MZI configuration is 10 mm, a homogeneous sensitivity of 7296.6%/refractive index unit (RIU) is obtained. Supposing the resolutions of the photoelectric detectors connected to the output ports are 0.2%, the MZI sensor can achieve a detection limit of 2.74 × 10(-6) RIU. Due to high coupling efficiency of SOI rib waveguide with large cross section with standard single-mode glass optical fiber, the proposed MZI sensing platform can be conveniently integrated with optical fiber communication systems and (opto-) electronic systems, and therefore has the potential to realize remote sensing, in situ real-time detecting, and possible applications in the internet of things. PMID:26343678

  1. Numerical study of turbulent nanofluid flow at the entrance region of a ribbed pipe

    NASA Astrophysics Data System (ADS)

    Ziaei-Rad, Masoud; Beigi, Maryam

    2016-03-01

    In this paper, we perform a numerical study on the heat transfer and pressure drop in hydraulically and thermally developing turbulent flow of nanofluid through an internally ribbed pipe. The effects of volume fraction of nanoparticles and the distance between the ribs are investigated on the heat transfer and skin friction coefficients at the entrance region of the pipe. The set of governing equations followed by a two-layer zonal turbulence model are solved numerically by a velocity-pressure coupling algorithm based on finite-volume method. Moreover, available empirical relations are used to calculate the nanofluid properties in terms of the nanoparticles and the base fluid. The obtained results illustrate that increasing the volume fraction of nanoparticles makes the thermal entrance length decrease and consequently, the heat transfer increases. It reveals that 10% increase in the volume fraction of nanoparticles causes about 15% rise in average Nusselt number. In addition, it is found that the friction factor rises by increasing the volume fraction of nanoparticles compared with turbulent flow of the base-fluid. Also, the average Nusselt number in nanofluid flow increases with the interval between the ribs compared with pure-fluid flow.

  2. Extraordinary incidence of cervical ribs indicates vulnerable condition in Late Pleistocene mammoths.

    PubMed

    Reumer, Jelle W F; Ten Broek, Clara M A; Galis, Frietson

    2014-01-01

    The number of cervical vertebrae in mammals is highly conserved at seven. We have shown that changes of this number are selected against due to a coupling with major congenital abnormalities (pleiotropic effects). Here we show that the incidence of abnormal cervical vertebral numbers in Late Pleistocene mammoths from the North Sea is high (33.3%) and approximately 10 times higher than that of extant elephants (3.6%). Abnormal numbers were due to the presence of large cervical ribs on the seventh vertebra, which we deduced from the presence of rib articulation facets on sixth (posterior side) and seventh (anterior side) cervical vertebrae. The incidence of abnormal cervical vertebral numbers in mammoths appears to be much higher than in other mammalian species, apart from exceptional sloths, manatees and dugongs and indicates a vulnerable condition. We argue that the increased incidence of cervical ribs in mammoths is probably caused by inbreeding and adverse conditions that impact early pregnancies in declining populations close to extinction in the Late Pleistocene. PMID:24711969

  3. Numerical Simulation and Observational Analysis of the Bora of Pag's Ribs

    NASA Astrophysics Data System (ADS)

    Trošić, Tanja; Trošić, Živko

    2010-02-01

    The severe bora case that lasted from 13 to 15 November 2004 has been selected for the analysis of the bora of Pag’s ribs, which occurs in the northern part of the eastern Adriatic coast over the Pag island area (Croatia). According to the measurements from automatic stations, the MM5 numerical model is successful in the 10-min mean wind speed prediction at 10-m height. The vertical analysis of the wind speed and potential temperature also gave satisfactory results. At the commencement of the bora the modelled wind had a magnitude of 20ms-1 at 10-m height in the Pag island area, which sharply attenuated in the cross direction and to the open sea. In this way the model has proved successful in predicting the characteristics of the bora of Pag’s ribs. Potential vorticity (PV) at 600m has lower values within PV banners than during the developed bora. The consequence is a strong jet emanating from the nearest gap. The vertical cross-sections through the centre of the gap point out a permanent hydraulic-like flow. At the time of the bora of Pag’s ribs the highest modelled turbulent kinetic energy is found in the jump-like region above the inversion and within the boundary layer along the lower boundary, ranging from 6-8m2 s-2. It is concluded that the dissipation in the hydraulic jumps and the wave breaking regions are the reasons for PV generation.

  4. Hybrid RANS/LES of turbulent flow in a rotating rib-roughened channel

    NASA Astrophysics Data System (ADS)

    Xun, Qian-Qiu; Wang, Bing-Chen

    2016-07-01

    In this paper, we investigate the effect of the Coriolis force on the flow field in a rib-roughened channel subjected to either clockwise or counter-clockwise system rotation using hybrid RANS/LES based on wall modelling. A simplified dynamic forcing scheme incorporating backscatter is proposed for the hybrid simulation approach. The flow is characterized by a Reynolds number of Re = 1.5 × 104 and a rotation number Ro ranging from -0.6 to 0.6. The mean flow speed and turbulence level near the roughened wall are enhanced under counter-clockwise rotation and suppressed under clockwise rotation. The Coriolis force significantly influences the stability of the wall shear layer and the free shear layers generated by the ribs. Consequently, it is interesting to observe that the classification of the roughness type relies not only on the pitch ratio, but also on the rotation number in the context of rotating rib-roughened flows. In order to validate the present hybrid approach, the first- and second-order statistical moments of the velocity field obtained from the simulations are thoroughly compared with the available laboratory measurement data.

  5. Simulation Analysis of Air Flow and Turbulence Statistics in a Rib Grit Roughened Duct

    PubMed Central

    Vogiatzis, I. I.; Denizopoulou, A. C.; Ntinas, G. K.; Fragos, V. P.

    2014-01-01

    The implementation of variable artificial roughness patterns on a surface is an effective technique to enhance the rate of heat transfer to fluid flow in the ducts of solar air heaters. Different geometries of roughness elements investigated have demonstrated the pivotal role that vortices and associated turbulence have on the heat transfer characteristics of solar air heater ducts by increasing the convective heat transfer coefficient. In this paper we investigate the two-dimensional, turbulent, unsteady flow around rectangular ribs of variable aspect ratios by directly solving the transient Navier-Stokes and continuity equations using the finite elements method. Flow characteristics and several aspects of turbulent flow are presented and discussed including velocity components and statistics of turbulence. The results reveal the impact that different rib lengths have on the computed mean quantities and turbulence statistics of the flow. The computed turbulence parameters show a clear tendency to diminish downstream with increasing rib length. Furthermore, the applied numerical method is capable of capturing small-scale flow structures resulting from the direct solution of Navier-Stokes and continuity equations. PMID:25057511

  6. Extraordinary incidence of cervical ribs indicates vulnerable condition in Late Pleistocene mammoths

    PubMed Central

    Reumer, Jelle W.F.; ten Broek, Clara M.A.

    2014-01-01

    The number of cervical vertebrae in mammals is highly conserved at seven. We have shown that changes of this number are selected against due to a coupling with major congenital abnormalities (pleiotropic effects). Here we show that the incidence of abnormal cervical vertebral numbers in Late Pleistocene mammoths from the North Sea is high (33.3%) and approximately 10 times higher than that of extant elephants (3.6%). Abnormal numbers were due to the presence of large cervical ribs on the seventh vertebra, which we deduced from the presence of rib articulation facets on sixth (posterior side) and seventh (anterior side) cervical vertebrae. The incidence of abnormal cervical vertebral numbers in mammoths appears to be much higher than in other mammalian species, apart from exceptional sloths, manatees and dugongs and indicates a vulnerable condition. We argue that the increased incidence of cervical ribs in mammoths is probably caused by inbreeding and adverse conditions that impact early pregnancies in declining populations close to extinction in the Late Pleistocene. PMID:24711969

  7. Study of heat transfer due to turbulent flow of nanofluids through rib-groove channel

    NASA Astrophysics Data System (ADS)

    Al-Shamani, A. N.; Sopian, K.; Abed, A. M.; Alghoul, M. A.; Ruslan, M. H.; Mat, S.

    2015-09-01

    Nanofluids for improve characteristics flow in a rib-groove channel are investigate. The continuity, momentum and energy equations were solved by FLUENT program. The bottom wall of channel is heated while the upper wall is symmetry, the left side velocity inlet, and the right side is outlet (pressure out). Four different rib-groove shapes are used. Four different types of nanoparticles, Al2O3, CuO, SiO2, and ZnO with different volumes fractions in the range of 1% to 4% and different nanoparticle diameter in the range of 25 nm to 70 nm, are dispersed in the base fluid water are used. In this paper, several parameters such as different Reynolds numbers in the range of 10000 < Re < 40000 are investigated. The numerical results indicate that the trapezoidal with increasing height in the flow direction rib- trapezoidal groove has the best heat transfer and high Nusselt number; the nanofluids with SiO2 have the best behavior. The Nusselt number increases as the volume fraction increases and it decreases as the nanoparticle diameter increases.

  8. The red-eared slider turtle carapace under fatigue loading: The effect of rib-suture arrangement.

    PubMed

    Achrai, Ben; Daniel Wagner, H

    2015-08-01

    Biological structures consisting of strong boney elements interconnected by compliant but tough collagenous sutures are abundantly found in skulls and shells of, among others, armadillos, alligators, turtles and more. In the turtle shell, a unique arrangement of alternating rigid (rib) and flexible (suture) elements gives rise to superior mechanical performance when subjected to low and high strain-rate loadings. However, the resistance to repeated load cycling - fatigue - of the turtle shell has yet to be examined. Such repeated loading could approximately simulate the consecutive high-stress bending loads exerted during (a predator) biting or clawing. In the present study flexural high-stress cyclic loads were applied to rib and suture specimens, taken from the top dorsal part of the red-eared slider turtle shell, termed carapace. Subsequently, to obtain a more complete and integrated fatigue behavior of the carapace, specimens containing a complex alternating rib-suture-rib-suture-rib configuration were tested as well. Although the sutures were found to be the least resistant to repeated loads, a synergistic effect was observed for the complex specimens, displaying improved fatigue durability compared to the individual (suture or even rib) constituents. This study may assist in the design of future high-stress fatigue-resistant materials incorporating complex assemblies of rigid and flexible elements. PMID:26042699

  9. Heat transfer performance comparison of steam and air in gas turbine cooling channels with different rib angles

    NASA Astrophysics Data System (ADS)

    Shi, Xiaojun; Gao, Jianmin; Xu, Liang; Li, Fajin

    2013-11-01

    Using steam as working fluid to replace compressed air is a promising cooling technology for internal cooling passages of blades and vanes. The local heat transfer characteristics and the thermal performance of steam flow in wide aspect ratio channels ( W/ H = 2) with different angled ribs on two opposite walls have been experimentally investigated in this paper. The averaged Nusselt number ratios and the friction factor ratios of steam and air in four ribbed channels were also measured under the same test conditions for comparison. The Reynolds number range is 6,000-70,000. The rib angles are 90°, 60°, 45°, and 30°, respectively. The rib height to hydraulic diameter ratio is 0.047. The pitch-to-rib height ratio is 10. The results show that the Nusselt number ratios of steam are 1.19-1.32 times greater than those of air over the range of Reynolds numbers studied. For wide aspect ratio channels using steam as the coolant, the 60° angled ribs has the best heat transfer performance and is recommended for cooling design.

  10. Study of the temperature rise induced by a focusing transducer with a wide aperture angle on biological tissue containing ribs

    NASA Astrophysics Data System (ADS)

    Xin, Wang; Jiexing, Lin; Xiaozhou, Liu; Jiehui, Liu; Xiufen, Gong

    2016-04-01

    We used the spheroidal beam equation to calculate the sound field created by focusing a transducer with a wide aperture angle to obtain the heat deposition, and then we used the Pennes bioheat equation to calculate the temperature field in biological tissue with ribs and to ascertain the effects of rib parameters on the temperature field. The results show that the location and the gap width between the ribs have a great influence on the axial and radial temperature rise of multilayer biological tissue. With a decreasing gap width, the location of the maximum temperature rise moves forward; as the ribs are closer to the transducer surface, the sound energy that passes through the gap between the ribs at the focus decreases, the maximum temperature rise decreases, and the location of the maximum temperature rise moves forward with the ribs. Project supported by the National Basic Research Program of China (Grant Nos. 2012CB921504 and 2011CB707902), the National Natural Science Foundation of China (Grant No. 11274166), the Fundamental Research Funds for the Central Universities, China (Grant No. 020414380001), the Fund from State Key Laboratory of Acoustics, Chinese Academy of Sciences (Grant No. SKLA201401), China Postdoctoral Science Foundation (Grant No. 2013M531313), and the Priority Academic Program Development of Jiangsu Higher Education Institutions and SRF for ROCS, SEM.

  11. The type I activin receptor ActRIB is required for egg cylinder organization and gastrulation in the mouse

    PubMed Central

    Gu, Zhenyu; Nomura, Masatoshi; Simpson, Brenda B.; Lei, Hong; Feijen, Alie; van den Eijnden-van Raaij, Janny; Donahoe, Patricia K.; Li, En

    1998-01-01

    ActRIB is a type I transmembrane serine/threonine kinase receptor that has been shown to form heteromeric complexes with the type II activin receptors to mediate activin signal. To investigate the function of ActRIB in mammalian development, we generated ActRIB-deficient ES cell lines and mice by gene targeting. Analysis of the ActRIB−/− embryos showed that the epiblast and the extraembryonic ectoderm were disorganized, resulting in disruption and developmental arrest of the egg cylinder before gastrulation. To assess the function of ActRIB in mesoderm formation and gastrulation, chimera analysis was conducted. We found that ActRIB−/− ES cells injected into wild-type blastocysts were able to contribute to the mesoderm in chimeric embryos, suggesting that ActRIB is not required for mesoderm formation. Primitive streak formation, however, was impaired in chimeras when ActRIB−/− cells contributed highly to the epiblast. Further, chimeras generated by injection of wild-type ES cells into ActRIB−/− blastocysts formed relatively normal extraembryonic tissues, but the embryo proper developed poorly probably resulting from severe gastrulation defect. These results provide genetic evidence that ActRIB functions in both epiblast and extraembryonic cells to mediate signals that are required for egg cylinder organization and gastrulation. PMID:9512518

  12. Osteometric sex discrimination from the sternal extremity of the fourth rib in a recent forensic sample from Southwestern Spain.

    PubMed

    Macaluso, P James; Rico, Antonio; Santos, María; Lucena, Joaquín

    2012-11-30

    The discrimination of sex is central to the process of establishing a personal identification from human skeletal remains. Previous study has demonstrated that osteometric analysis of the sternal extremity of the fourth rib provides a reasonably accurate method for assessing this biological attribute in diverse human groups. As metric standards are generally population-specific, the purpose of the current research was to evaluate the degree of sexual dimorphism present in the fourth rib among contemporary Spaniards, a group thus far not investigated, and generate discriminant function equations which can be used to estimate the sex of unidentified remains in this population. Superior-inferior height and anterior-posterior breadth dimensions of the fourth rib were collected for a sample consisting of 60 males and 57 females derived from postmortem examinations performed at the Institute of Legal Medicine, Seville, Spain. The results demonstrated that both rib dimensions were highly sexually dimorphic (p<0.0001) in this Spanish sample. Univariate discriminant function analyses yielded correct sex classification rates of 76.9% and 83.8% for breadth and height dimensions, respectively. Multivariate analysis incorporating both rib measurements improved the allocation accuracy to 86.3%, with an associated sex bias of only 0.7%. Therefore, the derived discriminant function equations, particularly those that incorporate rib height, can be effectively used in cases involving fragmentary remains in which more dimorphic elements such as the pelvis are not preserved, as well as complete skeletons to complement other metric and morphological sex assessment methods. PMID:23068090

  13. Missed rib fractures on evaluation of initial chest CT for trauma patients: pattern analysis and diagnostic value of coronal multiplanar reconstruction images with multidetector row CT

    PubMed Central

    Cho, S H; Sung, Y M; Kim, M S

    2012-01-01

    Objective The objective of this study was to review the prevalence and radiological features of rib fractures missed on initial chest CT evaluation, and to examine the diagnostic value of additional coronal images in a large series of trauma patients. Methods 130 patients who presented to an emergency room for blunt chest trauma underwent multidetector row CT of the thorax within the first hour during their stay, and had follow-up CT or bone scans as diagnostic gold standards. Images were evaluated on two separate occasions: once with axial images and once with both axial and coronal images. The detection rates of missed rib fractures were compared between readings using a non-parametric method of clustered data. In the cases of missed rib fractures, the shapes, locations and associated fractures were evaluated. Results 58 rib fractures were missed with axial images only and 52 were missed with both axial and coronal images (p=0.088). The most common shape of missed rib fractures was buckled (56.9%), and the anterior arc (55.2%) was most commonly involved. 21 (36.2%) missed rib fractures had combined fractures on the same ribs, and 38 (65.5%) were accompanied by fracture on neighbouring ribs. Conclusion Missed rib fractures are not uncommon, and radiologists should be familiar with buckle fractures, which are frequently missed. Additional coronal imagescan be helpful in the diagnosis of rib fractures that are not seen on axial images. PMID:22514102

  14. Experimental investigation of cross-over jets in a rib-roughened trailing-edge cooling channel

    NASA Astrophysics Data System (ADS)

    Xue, Fei

    Increasing the rotor inlet temperature can dramatically increase the efficiency and power output of the gas turbine engine. However, the melting point of turbine blade material limits the realistic upper bound of the rotor inlet temperature. As a result, the development of high temperature turbine blade material and advanced turbine blade cooling technology determines the future of turbine blade engine. Adding impingement jet holes and rib turbulators in the inner cooling channel of the gas turbine blades are two effective ways to enhance the cooling effects. The purpose of this study is to figure out the influence of different combinations of jet holes and rib turbulators on the heat transfer efficiency. A tabletop scale test model is used in the study to simulate the cooling cavity of trailing edge and its feed channel in a real gas turbine blade. The Dimensional Analysis Theory is used in the study to eliminate the influence of scaling. Two different crossover slots are tested with 5 different rib arrangements, and each of the test geometries is tested for 6 jet Reynolds numbers ranging from 10,000 to 36,000. The two different crossover slots are the crossover slots with 0 and 5 degree tilt angles. The four different rib arrangements are ribs with 0 degree, 45 degree, 90 degree and 135 degree angles of attack with respect to the flow direction. Furthermore, a smooth test section (no ribs) was also tested. The steady state liquid crystal thermography is used to quantify the heat transfer performance of the target areas. The variation of Nusselt number versus Reynolds number is plotted for each of the 10 geometries. Also, the variation of Nusselt number versus Reynolds number are compared for different rib angles of attack with the same crossover slot tilt angle, and between different crossover slots tilt angles with the same rib angle. The results show that, the area-weighted average Nusselt number increases monotonically with the Reynolds number; the target

  15. Experimental investigation of heat transfer and flow using V and broken V ribs within gas turbine blade cooling passage

    NASA Astrophysics Data System (ADS)

    Kumar, Sourabh; Amano, R. S.

    2015-05-01

    Gas turbines are extensively used for aircraft propulsion, land-based power generation, and various industrial applications. With an increase in turbine rotor inlet temperatures, developments in innovative gas turbine cooling technology enhance the efficiency and power output; these advancements of turbine cooling have allowed engine designs to exceed normal material temperature limits. For internal cooling design, techniques for heat extraction from the surfaces exposed to hot stream of gas are based on an increase in the heat transfer areas and on the promotion of turbulence of the cooling flow. In this study, an improvement in performance is obtained by casting repeated continuous V- and broken V-shaped ribs on one side of the two pass square channels into the core of the blade. A detailed experimental investigation is done for two pass square channels with a 180° turn. Detailed heat transfer distribution occurring in the ribbed passage is reported for a steady state experiment. Four different combinations of 60° V- and broken 60° V-ribs in a channel are considered. A series of thermocouples are used to obtain the temperature on the channel surface and local heat transfer coefficients are obtained for Reynolds numbers 16,000, 56,000 and 85,000 within the turbulent flow regime. Area averaged data are calculated in order to compare the overall performance of the tested ribbed surface and to evaluate the degree of heat transfer enhancement induced by the rib. Flow within the channels is characterized by heat transfer enhancing ribs, bends, rotation and buoyancy effects. A series of experimental measurements is performed to predict the overall performance of the channel. This paper presents an attempt to collect information about the Nusselt number, the pressure drop and the overall performance of the eight different ribbed ducts at the specified Reynolds number. The main contribution of this study is to evaluate the best combination of rib arrangements

  16. RibM from Streptomyces davawensis is a riboflavin/roseoflavin transporter and may be useful for the optimization of riboflavin production strains

    PubMed Central

    2011-01-01

    Background The bacterium Bacillus subtilis, which is not a natural riboflavin overproducer, has been converted into an excellent production strain by classical mutagenesis and metabolic engineering. To our knowledge, the enhancement of riboflavin excretion from the cytoplasm of overproducing cells has not yet been considered as a target for (further) strain improvement. Here we evaluate the flavin transporter RibM from Streptomyces davawensis with respect to improvement of a riboflavin production strain. Results The gene ribM from S. davawensis, coding for a putative facilitator of riboflavin uptake, was codon optimized (ribMopt) for expression in B. subtilis. The gene ribMopt was functionally introduced into B. subtilis using the isopropyl-β-thiogalactopyranoside (IPTG)-inducible expression plasmid pHT01: Northern-blot analysis of total RNA from IPTG treated recombinant B. subtilis cells revealed a ribMopt specific transcript. Western blot analysis showed that the his6-tagged heterologous gene product RibM was present in the cytoplasmic membrane. Expression of ribM in Escherichia coli increased [14C]riboflavin uptake, which was not affected by the protonophore carbonyl cyanide m-chlorophenylhydrazone (CCCP). Expression of ribMopt supported growth of a B. subtilis ΔribB::Ermr ΔribU::Kanr double mutant deficient in riboflavin synthesis (ΔribB) and also deficient with respect to riboflavin uptake (ΔribU). Expression of ribMopt increased roseoflavin (a toxic riboflavin analog produced by S. davawensis) sensitivity of a B. subtilis ΔribU::Kanr strain. Riboflavin synthesis by a model riboflavin B. subtilis production strain overproducing RibM was increased significantly depending on the amount of the inducer IPTG. Conclusions The energy independent flavin facilitator RibM could in principle catalyze riboflavin export and thus may be useful to increase the riboflavin yield in a riboflavin production process using a recombinant RibM overproducing B. subtilis strain

  17. Rib Fracture Fixation Restores Inspiratory Volume and Peak Flow in a Full Thorax Human Cadaveric Breathing Model

    PubMed Central

    Slobogean, Gerard P.; Kim, Hyunchul; Russell, Joseph P.; Stockton, David J.; Hsieh, Adam H.; O’Toole, Robert V.

    2015-01-01

    Background: Multiple rib fractures cause significant pain and potential for chest wall instability. Despite an emerging trend of surgical management of flail chest injuries, there are no studies examining the effect of rib fracture fixation on respiratory function. Objectives: Using a novel full thorax human cadaveric breathing model, we sought to explore the effect of flail chest injury and subsequent rib fracture fixation on respiratory outcomes. Patients and Methods: We used five fresh human cadavers to generate negative breathing models in the left thorax to mimic physiologic respiration. Inspiratory volumes and peak flows were measured using a flow meter for all three chest wall states: intact chest, left-sided flail chest (segmental fractures of ribs 3 - 7), and post-fracture open reduction and internal fixation (ORIF) of the chest wall with a pre-contoured rib specific plate fixation system. Results: A wide variation in the mean inspiratory volumes and peak flows were measured between specimens; however, the effect of a flail chest wall and the subsequent internal fixation of the unstable rib fractures was consistent across all samples. Compared to the intact chest wall, the inspiratory volume decreased by 40 ± 19% in the flail chest model (P = 0.04). Open reduction and internal fixation of the flail chest returned the inspiratory volume to 130 ± 71% of the intact chest volumes (P = 0.68). A similar 35 ± 19% decrease in peak flows was seen in the flail chest (P = 0.007) and this returned to 125 ± 71% of the intact chest following ORIF (P = 0.62). Conclusions: Negative pressure inspiration is significantly impaired by an unstable chest wall. Restoring mechanical stability of the fractured ribs improves respiratory outcomes similar to baseline values. PMID:26848471

  18. Rib fractures in chronic alcoholic men: Relationship with feeding habits, social problems, malnutrition, bone alterations, and liver dysfunction.

    PubMed

    González-Reimers, Emilio; García-Valdecasas-Campelo, Elena; Santolaria-Fernández, Francisco; Milena-Abril, Antonio; Rodríguez-Rodríguez, Eva; Martínez-Riera, Antonio; Pérez-Ramírez, Alina; Alemán-Valls, María Remedios

    2005-10-01

    Rib fractures are common in alcoholics. This high prevalence might be due to ethanol-associated malnutrition, bone disease, liver dysfunction, or the peculiar lifestyle of the alcoholic with frequent trauma and altercations. In this study we try to discern the role of these factors on rib fracture (assessed on a plain thoracic X-ray film) in 81 consecutive alcoholic patients, 25 of them cirrhotics. Serum albumin, prothrombin aspartate aminotransferase (ASAT), alanine aminotransferase (ALAT), gamma-glutamyl transpeptidase, C-terminal cross-linking telopeptide of type 1 collagen, osteocalcin, insulin growth factor 1, 1,25-dihydroxyvitamin D, parathyroid hormone, estradiol, free testosterone, and corticosterone were measured, and the patients also underwent assessment of bone mineral density by a HOLOGIC QDR-2000 bone densitometer (Waltham, MA, USA). Body mass index, triceps skinfold, and brachial perimeter were also determined, and the patients and their families were asked about tobacco consumption, social and familial links, consumption of ethanol by other members of the family, kind of job, and feeding habits. Forty-two male nondrinker sanitary workers of similar age served as controls. Forty of the 81 patients showed rib fractures. There was a statistically significant association between rib fractures and disruption of social and familial links, irregular feeding habits (in bars or pubs, not at home), ethanol consumption by close relatives, and intensity of tobacco consumption, but not between rib fractures and liver function tests, nutritional parameters, or bone mineral density, besides a nearly significant trend (p = .053) with the presence of osteopenia at the femoral neck. Patients with major withdrawal symptoms at admission also presented more frequent rib fractures. We conclude that rib fractures in alcoholics are related to the peculiar lifestyle of these patients rather than to bone alterations, liver dysfunction, or nutritional status. PMID:16584975

  19. The role of acoustic nonlinearity in tissue heating behind the rib cage using high intensity focused ultrasound phased array

    PubMed Central

    Yuldashev, Petr V.; Shmeleva, Svetlana M.; Ilyin, Sergey A.; Sapozhnikov, Oleg A.; Gavrilov, Leonid R.; Khokhlova, Vera A.

    2013-01-01

    The goal of this study was to investigate theoretically the effects of nonlinear propagation in a high intensity focused ultrasound (HIFU) field produced by a therapeutic phased array and the resultant heating of tissue behind a rib cage. Three configurations of focusing were simulated: in water, in water with ribs in the beam path, and in water with ribs backed by a layer of soft tissue. The Westervelt equation was used to model the nonlinear HIFU field and a 1 MHz phased array consisting of 254 circular elements was used as a boundary condition to the model. The temperature rise in tissue was modelled using the bioheat equation, and thermally necrosed volumes were calculated using the thermal dose formulation. The shapes of lesions predicted by the modelling were compared with those previously obtained in in vitro experiments at low power sonications. Intensity levels at the face of the array elements that corresponded to formation of high amplitude shock fronts in the focal region were determined as 10 W·cm−2 in the free field in water and 40 W·cm−2 in the presence of ribs. It was shown that exposures with shocks provided a substantial increase in tissue heating, and its better spatial localization in the main focal region only. The relative effects of overheating ribs and splitting of the focus due to the periodic structure of the ribs were therefore reduced. These results suggest that utilizing nonlinear propagation and shock formation effects can be beneficial for inducing confined HIFU lesions when irradiating through obstructions such as ribs. Design of compact therapeutic arrays to provide maximum power outputs with lower intensity levels at the elements is necessary to achieve shock wave regimes for clinically relevant sonication depths in tissue. PMID:23528338

  20. Short-Rib Polydactyly and Jeune Syndromes Are Caused by Mutations in WDR60

    PubMed Central

    McInerney-Leo, Aideen M.; Schmidts, Miriam; Cortés, Claudio R.; Leo, Paul J.; Gener, Blanca; Courtney, Andrew D.; Gardiner, Brooke; Harris, Jessica A.; Lu, Yeping; Marshall, Mhairi; Scambler, Peter J.; Beales, Philip L.; Brown, Matthew A.; Zankl, Andreas; Mitchison, Hannah M.; Duncan, Emma L.; Wicking, Carol

    2013-01-01

    Short-rib polydactyly syndromes (SRPS I–V) are a group of lethal congenital disorders characterized by shortening of the ribs and long bones, polydactyly, and a range of extraskeletal phenotypes. A number of other disorders in this grouping, including Jeune and Ellis-van Creveld syndromes, have an overlapping but generally milder phenotype. Collectively, these short-rib dysplasias (with or without polydactyly) share a common underlying defect in primary cilium function and form a subset of the ciliopathy disease spectrum. By using whole-exome capture and massive parallel sequencing of DNA from an affected Australian individual with SRPS type III, we detected two novel heterozygous mutations in WDR60, a relatively uncharacterized gene. These mutations segregated appropriately in the unaffected parents and another affected family member, confirming compound heterozygosity, and both were predicted to have a damaging effect on the protein. Analysis of an additional 54 skeletal ciliopathy exomes identified compound heterozygous mutations in WDR60 in a Spanish individual with Jeune syndrome of relatively mild presentation. Of note, these two families share one novel WDR60 missense mutation, although haplotype analysis suggested no shared ancestry. We further show that WDR60 localizes at the base of the primary cilium in wild-type human chondrocytes, and analysis of fibroblasts from affected individuals revealed a defect in ciliogenesis and aberrant accumulation of the GLI2 transcription factor at the centrosome or basal body in the absence of an obvious axoneme. These findings show that WDR60 mutations can cause skeletal ciliopathies and suggest a role for WDR60 in ciliogenesis. PMID:23910462

  1. Fiber orientation structures and mechanical properties of injection molded short glass fiber-reinforced nylon ribbed plates

    SciTech Connect

    Wire, S.L.; Hine, P.J.; Duckett, R.A.; O`Gara, J.G.

    1996-12-31

    The work presented in this paper, sponsored by General Motors, describes a study of injection moulded ribbed plates of short glass fibre-reinforced Nylon. Ribs have been placed both parallel and perpendicular to the injection direction in an attempt to simulate the likely geometry of an actual automotive part. The complex orientation structures developed within these ribbed samples during injection moulding have been determined within both the parallel and perpendicular ribs, and for the regions between these structures using an automated image analysis system developed in-house by our colleagues at the University of Leeds Instrumentation Group. This system allows the rapid measurement of accurate fibre orientation data over large sample areas (mm {times} mm) enabling thousands of fibre images to be sampled. Mechanical properties both between and underneath the rib structures have been measured using the ultrasonic immersion technique, and these have been compared with theoretical predictions, determined using the measured fibre orientation averages and simple composite models developed within this laboratory. In general the agreement between theory and experiment is excellent.

  2. The 'Pro-Drug' RibCys Decreases The Mutagenicity of High LET Radiation in Cultured Mammalian Cells

    NASA Technical Reports Server (NTRS)

    Lenarczyk, M.; Ueno, A.; Vannais, D. B.; Kraemer, S.; Kronenberg, A.; Roberts, J. C.; Tatsumi, K.; Hei, T. K.; Waldren, C. A.

    2000-01-01

    We have initiated studies aimed at reducing the mutational effects of high LET radiation such as Fe-56 ions and C-12 ions with certain drugs. The mutagenicity of high LET (143 keV/micrometer) Fe-56 or C-12 ions (LET = 100 keV/micrometer) was quantified at the CD59 locus of human-hamster hybrid AL cells. RibCys [2,S)-D-ribo-(1',2',3',4'- Tetrahydroxybutyl)-thiazolidine-4(R)-ca riboxylic acid], formed by condensation of L-cysteine with D-ribose, is designed so that the sulfhydryl amino acid L-cysteine is released intracellularly via nonenzymatic ring opening and hydrolysis leading to increased levels of glutathione (GSH). RibCys (4 or 10 mM), present during irradiation and a few hours post-irradiation, significantly decreased the yield of CD59(-) mutants induced by radiation. RibCys did not affect the clonogenic survival of irradiated cells, nor was it mutagenic itself. These results, together with the minimal side effects reported in mice and pigs, indicate that RibCys may be useful, perhaps even when used prophylactically, in reducing the load of mutations created by high LET radiation in astronauts or other exposed individuals. RibCys is an attractive drug that may reduce the risk of carcinogenesis in people exposed to high LET radiation.

  3. Pressure Distribution over a Wing and Tail Rib of a VE-7 and of a TS Airplane in Flight

    NASA Technical Reports Server (NTRS)

    Crowley, J W , Jr

    1928-01-01

    This investigation was made to determine the pressure distribution over a rib of the wing and over a rib of the horizontal tail surface of an airplane in flight and to obtain information as to the time correlation of the loads occurring on these ribs. Two airplanes, VE-7 and TS, were selected in order to obtain the information for a thin and a thick wing section. In each case the pressure distribution was recorded for the full range of angle of attack in level flight and throughout violent maneuvers. The results show: (a) that the present rib load specifications in use by the Army Air Corps and the Bureau of Aeronautics, Navy Department, are in fair agreement with the loads actually occurring in flight, but could be slightly improved; (b) that there appears to be no definite sequence in which wing and tail surface ribs reach their respective maximum loads in different maneuvers; (c) that in accelerated flight, at air speeds less than or equal to 60 per cent of the maximum speed, the accelerations measured agree very closely with the theoretically possible maximum accelerations. In maneuvers at higher air speeds the observed accelerations were smaller than those theoretically possible. (author)

  4. Mode conversion in magneto-optic rib waveguide made by silica matrix doped with magnetic nanoparticles

    NASA Astrophysics Data System (ADS)

    Bouras, Mounir; Hocini, Abdessalem

    2016-03-01

    The TE-TM mode conversion is an important requirement for magneto-optical waveguide devices. It has been analyzed by means of a full-vectorial beam propagation method. The present work is based on the study of the influence of diagonal and off-diagonal elements of the complex dielectric tensor on the conversion efficiency in magneto-optical rib waveguide. We have found that in the presence of the absorption (taking into account the imaginary part of diagonal tensor) the conversion efficiency is affected by the absorption and these latter increases as the volume fraction of nanoparticles increases.

  5. Mode-expanded semiconductor laser with tapered-rib adiabatic-following fiber coupler

    SciTech Connect

    Vawter, G.A.; Smith, R.E.; Hou, H.; Wendt, J.R.

    1996-12-01

    Expanded-mode semiconductor lasers are of great interest due to the benefits of reduced far-field divergence and improved coupling efficiency to optical fiber. The authors present a new diode laser using a Tapered-Rib Adiabatic-Following Fiber Coupler (TRAFFiC) to achieve 2D mode expansion without epitaxial regrowth or sharply-defined tips on tapered waveguides. The expanded mode size would allow 0.25 to 1 dB coupling loss to standard telecommunications fiber making smaller-core specialty fibers unnecessary, increasing misalignment tolerance, and eliminating the need for coupling optics.

  6. Fracture of the clavicle and second rib: an indirect injury from tricep dips.

    PubMed

    Malavolta, Eduardo A; Assunção, Jorge H; Gracitelli, Mauro E; Lobo, Frederico L; Ferreira Neto, Arnaldo A

    2016-01-01

    Due to the recent rise in the interest in strength training, an increment in the number of lesions is expected, whether of the tendons, muscles, or bones. We describe a case of fracture involving the middle third of the clavicle and the second rib in a low-demand weightlifter. The fractures occurred suddenly while performing a triceps dips exercise, and the patient had no previous symptoms. He was treated conservatively and was able to return to sports six months later. To our knowledge, this is the first study describing the association of these fractures triggered by a single event of muscle contraction. PMID:27377364

  7. Numerical and Experimental Investigation of the Turbulent Flow in a Ribbed Serpentine Passage

    NASA Technical Reports Server (NTRS)

    Iaccarino, Gianluca; Kalitzin, Georgi; Elkins, Christopher J.

    2003-01-01

    In this paper, the turbulent flow in a serpentine with oblique ribs is investigated experimentally and by numerical simulations. The measurements are carried out by using Magnetic Resonance Velocimetry (MRV) and the simulations using the Immersed Boundary (IB) technique. A brief description of these two approaches is reported in following sections. The results are reported in terms of velocity distributions in various planes in the serpentine; differences between measurements and simulations are presented qualitatively and quantitatively. The study of the discrepancy allows us to identify areas of needed improvements in the turbulence modeling.

  8. Nd:Ta{sub 2}O{sub 5} rib waveguide lasers

    SciTech Connect

    Unal, Bayram; Tai, C.-Y.; Shepherd, David P.; Wilkinson, James S.; Perney, Nicolas M.B.; Netti, M. Caterina; Parker, Gregory J.

    2005-01-10

    Ta{sub 2}O{sub 5} waveguides offer great potential for high-density active photonic crystal circuits and their combination with rare-earth dopants for active devices is of interest for increasing their potential functionality. To this end, neodymium-doped Ta{sub 2}O{sub 5} rib waveguide lasers have been fabricated on an oxidized silicon wafer by rf sputtering and argon ion-beam milling and laser action in this material has been demonstrated. Lasing was observed at wavelenghts between 1060 and 1080 nm and an absorbed pump power threshold of 87 mW was obtained.

  9. Development and Validation of a Musculoskeletal Model of the Fully Articulated Thoracolumbar Spine and Rib Cage.

    PubMed

    Bruno, Alexander G; Bouxsein, Mary L; Anderson, Dennis E

    2015-08-01

    We developed and validated a fully articulated model of the thoracolumbar spine in opensim that includes the individual vertebrae, ribs, and sternum. To ensure trunk muscles in the model accurately represent muscles in vivo, we used a novel approach to adjust muscle cross-sectional area (CSA) and position using computed tomography (CT) scans of the trunk sampled from a community-based cohort. Model predictions of vertebral compressive loading and trunk muscle tension were highly correlated to previous in vivo measures of intradiscal pressure (IDP), vertebral loading from telemeterized implants and trunk muscle myoelectric activity recorded by electromyography (EMG). PMID:25901907

  10. Rib Fractures

    MedlinePlus

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  11. Effects of Mixed Bone and Brisket Meat on Physico-Chemical Characteristics of Shank Bone and Rib Extracts from Hanwoo.

    PubMed

    Choi, Hyung-Gyu; Choi, Hyun-Su; Choi, Young-Seok; Jung, Myung-Ok; Choi, Jung-Seok; Choi, Yang-Il

    2016-01-01

    This study was conducted to investigate the effects of mixed bone and brisket meat on the quality characteristics and nutritional components of shank bone extract and rib extract from Hanwoo. The pH values were influenced by the raw bones, mixed bone, brisket meat and their interactions (p<0.05). The salinity, sugar content, turbidity, and essential amino acid values increased significantly with addition of mixed bone and brisket meat. All attributes of sensory evaluation score were the highest in T6 (Rib 500 g + Mixed bone 500 g + Brisket meat 400 g) (p<0.05). The mixed bone significantly increased the saturated fatty acids of shank bone extract (p<0.001). Thus, the addition of mixed bone and brisket meat had a positive effect on the quality and nutritional components in shank and rib extracts of Hanwoo cattle. PMID:27499665

  12. Effects of Mixed Bone and Brisket Meat on Physico-Chemical Characteristics of Shank Bone and Rib Extracts from Hanwoo

    PubMed Central

    Jung, Myung-Ok; Choi, Jung-Seok

    2016-01-01

    This study was conducted to investigate the effects of mixed bone and brisket meat on the quality characteristics and nutritional components of shank bone extract and rib extract from Hanwoo. The pH values were influenced by the raw bones, mixed bone, brisket meat and their interactions (p<0.05). The salinity, sugar content, turbidity, and essential amino acid values increased significantly with addition of mixed bone and brisket meat. All attributes of sensory evaluation score were the highest in T6 (Rib 500 g + Mixed bone 500 g + Brisket meat 400 g) (p<0.05). The mixed bone significantly increased the saturated fatty acids of shank bone extract (p<0.001). Thus, the addition of mixed bone and brisket meat had a positive effect on the quality and nutritional components in shank and rib extracts of Hanwoo cattle. PMID:27499665

  13. Influence of UV-Curable Compositions and Rib Properties on Ink-Jet-Type Color Filter Performance

    NASA Astrophysics Data System (ADS)

    Chang, Chi-Jung; Wu, Feng-Mei; Chang, Shinn-Jen; Hsu, Mei-Wen

    2004-09-01

    UV-curable jet inks were ejected into a color area separated by barrier ribs, then fixed by UV curing reaction to prepare LCD color filter (CF). The widths of the color strip and rib were 90 μm and 20 μm, respectively. Either adding oligomer or increasing the amount of monomers can improve ink curability. By increasing the monomer content instead of incorporating the oligomer, the curing reactivity was elevated without deteriorating the pigment dispersion stability, jetting directionality and drop size uniformity. The drop formation behaviors were observed by the image-capture system. The ejected drops showed straight trajectory and uniform size without error and missing dots. The chemical resistance of the barrier ribs was improved to avoid collapse caused by ink corrosion.

  14. Mutations in mouse Ift144 model the craniofacial, limb and rib defects in skeletal ciliopathies.

    PubMed

    Ashe, Alyson; Butterfield, Natalie C; Town, Liam; Courtney, Andrew D; Cooper, Ashley N; Ferguson, Charles; Barry, Rachael; Olsson, Fredrik; Liem, Karel F; Parton, Robert G; Wainwright, Brandon J; Anderson, Kathryn V; Whitelaw, Emma; Wicking, Carol

    2012-04-15

    Mutations in components of the intraflagellar transport (IFT) machinery required for assembly and function of the primary cilium cause a subset of human ciliopathies characterized primarily by skeletal dysplasia. Recently, mutations in the IFT-A gene IFT144 have been described in patients with Sensenbrenner and Jeune syndromes, which are associated with short ribs and limbs, polydactyly and craniofacial defects. Here, we describe an N-ethyl-N-nitrosourea-derived mouse mutant with a hypomorphic missense mutation in the Ift144 gene. The mutant twinkle-toes (Ift144(twt)) phenocopies a number of the skeletal and craniofacial anomalies seen in patients with human skeletal ciliopathies. Like other IFT-A mouse mutants, Ift144 mutant embryos display a generalized ligand-independent expansion of hedgehog (Hh) signalling, in spite of defective ciliogenesis and an attenuation of the ability of mutant cells to respond to upstream stimulation of the pathway. This enhanced Hh signalling is consistent with cleft palate and polydactyly phenotypes in the Ift144(twt) mutant, although extensive rib branching, fusion and truncation phenotypes correlate with defects in early somite patterning and may reflect contributions from multiple signalling pathways. Analysis of embryos harbouring a second allele of Ift144 which represents a functional null, revealed a dose-dependent effect on limb outgrowth consistent with the short-limb phenotypes characteristic of these ciliopathies. This allelic series of mouse mutants provides a unique opportunity to uncover the underlying mechanistic basis of this intriguing subset of ciliopathies. PMID:22228095

  15. Scattering of the field of a multi-element phased array by human ribs

    NASA Astrophysics Data System (ADS)

    Gélat, P.; ter Haar, G.; Saffari, N.

    2012-03-01

    The efficacy of high intensity focused ultrasound (HIFU) for the non-invasive treatment of cancer has been demonstrated for a range of different cancers including those of the liver, kidney, prostate and breast. As a non-invasive focused therapy, HIFU offers considerable advantages over other techniques such as chemotherapy and surgical resection, in terms of invasiveness and risk of harmful side effects. Despite its advantages, however, there are a number of significant challenges currently hindering its widespread clinical application. One of these challenges is the need to transmit sufficient energy through the ribcage to induce tissue necrosis at the required foci whilst minimising the formation of side lobes. Multielement random arrays are currently showing great promise in overcoming the limitations of single-element transducers. Nevertheless, successfully treating a patient for liver tumours requires a thorough understanding of the way in which the ultrasonic pressure field from a HIFU array is scattered by the ribcage. A mesh of quadratic pressure patches was generated using CT scan data for ribs nine to twelve on the right side. A boundary element approach based on a Generalised Minimal Residual (GMRES) implementation of the Burton-Miller formulation was used, in conjunction with phase conjugation techniques to focus the field of a 256-element random HIFU array past the ribs at both intercostal and transcostal treatment locations. This method has the advantage of accounting for full effects of scattering and diffraction in three dimensions under continuous wave excitation.

  16. Mutations in mouse Ift144 model the craniofacial, limb and rib defects in skeletal ciliopathies

    PubMed Central

    Ashe, Alyson; Butterfield, Natalie C.; Town, Liam; Courtney, Andrew D.; Cooper, Ashley N.; Ferguson, Charles; Barry, Rachael; Olsson, Fredrik; Liem, Karel F.; Parton, Robert G.; Wainwright, Brandon J.; Anderson, Kathryn V.; Whitelaw, Emma; Wicking, Carol

    2012-01-01

    Mutations in components of the intraflagellar transport (IFT) machinery required for assembly and function of the primary cilium cause a subset of human ciliopathies characterized primarily by skeletal dysplasia. Recently, mutations in the IFT-A gene IFT144 have been described in patients with Sensenbrenner and Jeune syndromes, which are associated with short ribs and limbs, polydactyly and craniofacial defects. Here, we describe an N-ethyl-N-nitrosourea-derived mouse mutant with a hypomorphic missense mutation in the Ift144 gene. The mutant twinkle-toes (Ift144twt) phenocopies a number of the skeletal and craniofacial anomalies seen in patients with human skeletal ciliopathies. Like other IFT-A mouse mutants, Ift144 mutant embryos display a generalized ligand-independent expansion of hedgehog (Hh) signalling, in spite of defective ciliogenesis and an attenuation of the ability of mutant cells to respond to upstream stimulation of the pathway. This enhanced Hh signalling is consistent with cleft palate and polydactyly phenotypes in the Ift144twt mutant, although extensive rib branching, fusion and truncation phenotypes correlate with defects in early somite patterning and may reflect contributions from multiple signalling pathways. Analysis of embryos harbouring a second allele of Ift144 which represents a functional null, revealed a dose-dependent effect on limb outgrowth consistent with the short-limb phenotypes characteristic of these ciliopathies. This allelic series of mouse mutants provides a unique opportunity to uncover the underlying mechanistic basis of this intriguing subset of ciliopathies. PMID:22228095

  17. Mutations in DYNC2LI1 disrupt cilia function and cause short rib polydactyly syndrome

    PubMed Central

    Taylor, S. Paige; Dantas, Tiago J.; Duran, Ivan; Wu, Sulin; Lachman, Ralph S.; Nelson, Stanley F.; Cohn, Daniel H.; Vallee, Richard B.; Krakow, Deborah

    2015-01-01

    The short rib polydactyly syndromes (SRPS) are a heterogeneous group of autosomal recessive, perinatal-lethal skeletal disorders characterized primarily by short, horizontal ribs, short limbs, and poly-dactyly. Mutations in several genes affecting intraflagellar transport (IFT) cause SRPS but they do not account for all cases. Here we identify additional SRPS genes and further unravel the functional basis for IFT. We perform whole exome sequencing and identify mutations in a new disease-producing gene, cytoplasmic dynein-2 light intermediate chain 1, DYNC2LI1, segregating with disease in three families. Using primary fibroblasts, we show that DYNC2LI1 is essential for dynein-2 complex stability and that mutations in DYNC2LI1 result in variable-length, including hyperelongated, cilia, Hedgehog pathway impairment, and ciliary IFT accumulations. The findings in this study expand our understanding of SRPS locus heterogeneity and demonstrate the importance of DYNC2LI1 in dynein-2 complex stability, cilium function, Hedgehog regulation, and skeletogenesis. PMID:26077881

  18. An instability theory for the formation of ribbed moraine, drumlins and mega-scale glacial lineations

    PubMed Central

    Fowler, A. C.; Chapwanya, M.

    2014-01-01

    We present a theory for the coupled flow of ice, subglacial water and subglacial sediment, which is designed to represent the processes which occur at the bed of an ice sheet. The ice is assumed to flow as a Newtonian viscous fluid, the water can flow between the till and the ice as a thin film, which may thicken to form streams or cavities, and the till is assumed to be transported, either through shearing by the ice, squeezing by pressure gradients in the till, or by fluvial sediment transport processes in streams or cavities. In previous studies, it was shown that the dependence of ice sliding velocity on effective pressure provided a mechanism for the generation of bedforms resembling ribbed moraine, while the dependence of fluvial sediment transport on water film depth provides a mechanism for the generation of bedforms resembling mega-scale glacial lineations. Here, we combine these two processes in a single model, and show that, depending largely on the granulometry of the till, instability can occur in a range of types which range from ribbed moraine through three-dimensional drumlins to mega-scale glacial lineations. PMID:25383019

  19. An instability theory for the formation of ribbed moraine, drumlins and mega-scale glacial lineations.

    PubMed

    Fowler, A C; Chapwanya, M

    2014-11-01

    We present a theory for the coupled flow of ice, subglacial water and subglacial sediment, which is designed to represent the processes which occur at the bed of an ice sheet. The ice is assumed to flow as a Newtonian viscous fluid, the water can flow between the till and the ice as a thin film, which may thicken to form streams or cavities, and the till is assumed to be transported, either through shearing by the ice, squeezing by pressure gradients in the till, or by fluvial sediment transport processes in streams or cavities. In previous studies, it was shown that the dependence of ice sliding velocity on effective pressure provided a mechanism for the generation of bedforms resembling ribbed moraine, while the dependence of fluvial sediment transport on water film depth provides a mechanism for the generation of bedforms resembling mega-scale glacial lineations. Here, we combine these two processes in a single model, and show that, depending largely on the granulometry of the till, instability can occur in a range of types which range from ribbed moraine through three-dimensional drumlins to mega-scale glacial lineations. PMID:25383019

  20. Numerical sensitivity analysis of 3- and 2- dimensional rib-roughened channels

    NASA Astrophysics Data System (ADS)

    Keshmiri, Amir

    2012-07-01

    Rough surfaces have been used as a tool to enhance heat transfer by increasing the level of turbulence mixing in the flow. In numerically simulating such flows, it is common to simulate a 3D rib-roughened channel with a 2D domain in order to reduce the computational time and power. The main purpose of the present work is to investigate the accuracy of the above approximation. In order to do so, initially a 3D channel is simulated using Reynolds-Averaged Navier-Stokes technique and comparison is made against 2D simulations as well as experimental data. In addition, the effects of rib thermal boundary condition and near-wall treatments are also investigated. All computations are undertaken using the commercial CFD code `STAR-CD'. The Reynolds number, based on the channel bulk velocity and hydraulic diameter, is 30,000. Two low-Reynolds-number linear Eddy-Viscosity Models, namely the Lien-Chen-Leschziner k - ɛ model and a variant of Durbin's v 2 - f formulation are used. In the CFD simulations reported here, the focus is on the experimental data of Rau et al. (ASME J Turbomach 120:368-375, 1998). It was found that the present results for a 3D channel are in relatively good agreement with the data. It was also shown that a 2D channel can be used to represent the flow in the centre-line of a 3D channel with relatively good accuracy.

  1. Vertical expandable prosthetic titanium rib (VEPTR): indications, technique, and management review.

    PubMed

    Shah, Shailja C; Birknes, John K; Sagoo, Sukh; Thome, Shelby; Samdani, Amer F

    2009-04-01

    Surgical correction is generally indicated as the primary form of management in children with severe early onset scoliosis. Even so, conservative, nonsurgical treatment is always considered first, as surgical correction carries significant concomitant consequences, including but not limited to crankshaft phenomenon and, more importantly, inhibition of further spine, lung, and chest growth in skeletally immature patients. Fusionless surgical procedures assuage some of these risks, as they are characteristically associated with techniques necessitating spinal fusion. One device looks particularly promising in treating and managing severe early onset scoliosis, the vertical expandable prosthetic titanium rib (VEPTR)-a device that was initially targeted toward children with thoracic insufficiency syndrome (TIS). Despite its promising results in correction of severe early onset scoliosis, as well as associated rib and chest wall deformities, the VEPTR nevertheless has a complication rate comparable to other fusionless techniques. Continued modifications and research will hopefully beget a device that permits thoracic and spinal growth in skeletally immature patients yet with fewer postoperative complications. In this chapter, the authors review the clinical experience with VEPTR to date and present their results in 16 children with congenital scoliosis cared for at Shriners Hospital of Philadelphia. PMID:19585438

  2. Primary Ewing's sarcoma of the ribs. A report from the intergroup Ewing's sarcoma study.

    PubMed

    Thomas, P R; Foulkes, M A; Gilula, L A; Burgert, E O; Evans, R G; Kissane, J; Nesbit, M E; Pritchard, D J; Tefft, M; Vietti, T J

    1983-03-15

    Thirty-six patients with primary Ewing's sarcoma of the ribs have been reviewed. Of these, 21 had clinically localized disease at diagnosis and were entered on protocol IESS 7299, eight had regional and seven metastatic disease at diagnosis and were entered on protocol 7450. The 21 with localized disease were treated with surgical excision or biopsy, followed by local radiotherapy (in all but one patient) and randomization to one of three chemotherapy regimens. Eleven patients (52%) remain disease-free for periods ranging from 18 to 64 months, respectively. Seven of eight patients who underwent complete surgical excision of the primary lesion remain disease-free, compared with four of 12 (excluding one patient who died disease-free) who remain disease-free after partial excision or biopsy. However, analysis of size of tumor at diagnosis reveals that smaller primary tumors have a better prognosis irrespective of extent of surgery. Protocol IESS 7450, consisted of radiotherapy to all areas of known disease and four drug chemotherapy. Four (50%) with regional disease but none with metastatic disease have remained alive and continuously disease-free. It is concluded that an aggressive approach to Ewing's sarcoma of the ribs is justified by the results, as even regional disease may be curable. The apparent prognostic advantage for those patients undergoing surgical excision may be explained by patient selection. PMID:6821866

  3. A Rare Full-Term Newborn Case of Rib Osteomyelitis with Suspected Preceding Fracture.

    PubMed

    Ono, Sahoko; Fujimoto, Hiroki; Kawamoto, Yutaka

    2016-03-01

    Acute osteomyelitis is uncommon in full-term neonates and occurs most frequently in those with critical illnesses, often following episodes of sepsis, skin infection, umbilical catheterization, urinary tract anomalies, or a complicated delivery. Here, we report a very rare case of acute rib osteomyelitis due to Staphylococcus aureus in a 13-day-old full-term male neonate. Ultrasonography (US) enabled diagnosis and revealed a coexisting costochondral junction rib fracture, which was not detected on routine chest radiography. Following a 29-day course of intensive parenteral antibiotic therapy, the patient was discharged in good health at 42 days of age without any scar formation. Due to its accessibility and safety, US can be a promising modality for detecting acute osteomyelitis in neonates with clinically highly suspected conditions in the neonatal intensive care unit setting, particularly those involving thin and mobile bones subject to respiratory motion. However, further studies are required to assess the utility of US in these cases and negative results. In low-risk neonates with osteomyelitis, an accompanying fracture should be considered. PMID:26929860

  4. A Rare Full-Term Newborn Case of Rib Osteomyelitis with Suspected Preceding Fracture

    PubMed Central

    Ono, Sahoko; Fujimoto, Hiroki; Kawamoto, Yutaka

    2016-01-01

    Acute osteomyelitis is uncommon in full-term neonates and occurs most frequently in those with critical illnesses, often following episodes of sepsis, skin infection, umbilical catheterization, urinary tract anomalies, or a complicated delivery. Here, we report a very rare case of acute rib osteomyelitis due to Staphylococcus aureus in a 13-day-old full-term male neonate. Ultrasonography (US) enabled diagnosis and revealed a coexisting costochondral junction rib fracture, which was not detected on routine chest radiography. Following a 29-day course of intensive parenteral antibiotic therapy, the patient was discharged in good health at 42 days of age without any scar formation. Due to its accessibility and safety, US can be a promising modality for detecting acute osteomyelitis in neonates with clinically highly suspected conditions in the neonatal intensive care unit setting, particularly those involving thin and mobile bones subject to respiratory motion. However, further studies are required to assess the utility of US in these cases and negative results. In low-risk neonates with osteomyelitis, an accompanying fracture should be considered. PMID:26929860

  5. Jumbled spine and ribs (Jsr): a new mutation on mouse chromosome 5.

    PubMed

    Miyoshi, H; Kon, Y; Seo, K W; Jin, H K; Hasegawa, A; Watanabe, T

    1999-03-01

    Jumbled spine and ribs (Jsr) is an autosomal dominant mutation that results in malformation of the axial skeleton. The vertebrae of mutant mice (Jsr/+) are all shorter than those of normal mice (+/+) in the inbred line and show various abnormalities. In addition, several ribs are fused at their proximal region because of fusion of thoracic vertebrae. In this study, we localized the Jsr mutation on distal Chromosome (Chr) 5 and constructed a high-resolution map. Chromosomal mapping was performed with an inter-subspecific backcross of (CKH-Jsr/+ x MOG) F1 carrying the Jsr allele and CKH-+/+. The predicted gene order around Jsr was determined to be cen-(Epo, Pdgfa, D5Mit31, D5Mit374)-(Jsr, Nfe2u, D5Mit99, D5Mit247, D5Mit284, D5Mit292, D5Mit327)-D5Mit328-tel. Subsequently, high-resolution mapping concluded the Jsr localization to be cen-Nfe2u-1.0cM-Jsr-0.2cM-D5Mit247,292-tel . Jsr/Jsr homozygotes are alive, as the mutation is not lethal. Based on histological analysis of mutant embryos, Jsr is hypothesized to be caused by abnormal development of primordial cells in the axial skeleton. PMID:10051313

  6. Rib stress fractures among rowers: definition, epidemiology, mechanisms, risk factors and effectiveness of injury prevention strategies.

    PubMed

    McDonnell, Lisa K; Hume, Patria A; Nolte, Volker

    2011-11-01

    Rib stress fractures (RSFs) can have serious effects on rowing training and performance and accordingly represent an important topic for sports medicine practitioners. Therefore, the aim of this review is to outline the definition, epidemiology, mechanisms, intrinsic and extrinsic risk factors, injury management and injury prevention strategies for RSF in rowers. To this end, nine relevant books, 140 journal articles, the proceedings of five conferences and two unpublished presentations were reviewed after searches of electronic databases using the keywords 'rowing', 'rib', 'stress fracture', 'injury', 'mechanics' and 'kinetics'. The review showed that RSF is an incomplete fracture occurring from an imbalance between the rate of bone resorption and the rate of bone formation. RSF occurs in 8.1-16.4% of elite rowers, 2% of university rowers and 1% of junior elite rowers. Approximately 86% of rowing RSF cases with known locations occur in ribs four to eight, mostly along the anterolateral/lateral rib cage. Elite rowers are more likely to experience RSF than nonelite rowers. Injury occurrence is equal among sweep rowers and scullers, but the regional location of the injury differs. The mechanism of injury is multifactorial with numerous intrinsic and extrinsic risk factors contributing. Posterior-directed resultant forces arising from the forward directed force vector through the arms to the oar handle in combination with the force vector induced by the scapula retractors during mid-drive, or repetitive stress from the external obliques and rectus abdominis in the 'finish' position, may be responsible for RSF. Joint hypomobility, vertebral malalignment or low bone mineral density may be associated with RSF. Case studies have shown increased risk associated with amenorrhoea, low bone density or poor technique, in combination with increases in training volume. Training volume alone may have less effect on injury than other factors. Large differences in seat and handle

  7. Terahertz-wave generation by GaP rib waveguides via collinear phase-matched difference-frequency mixing of near-infrared lasers

    SciTech Connect

    Saito, Kyosuke; Tanabe, Tadao; Oyama, Yutaka; Suto, Ken; Nishizawa, Jun-ichi

    2009-03-15

    We constructed rib waveguides from GaP material using an inductively coupled plasma reactive ion etching technique based on Ar/Cl{sub 2} gas application. We obtained a waveguide with a rib height of 200 {mu}m. Terahertz-wave generation from the GaP-crystal rib waveguides was demonstrated via collinear phase-matched difference-frequency mixing of near-infrared light. The terahertz output peak corresponding to the fundamental modes appeared around 0.75 THz for a 1-mm-wide rib waveguide. The position of the fundamental mode shifted to 1.32 THz for a 200-{mu}m-wide waveguide, which is attributable to the two-dimensional confinement of the terahertz waves in the waveguide. The conversion efficiency was enhanced in the rib waveguide compared to that in both slab waveguides and bulk GaP crystals.

  8. Differences in rates of radiation-induced true and false rib fractures after stereotactic body radiation therapy for Stage I primary lung cancer

    PubMed Central

    Miura, Hideharu; Inoue, Toshihiko; Shiomi, Hiroya; Oh, Ryoong-Jin

    2015-01-01

    The purpose of this study was to analyze the dosimetry and investigate the clinical outcomes of radiation-induced rib fractures (RIRFs) after stereotactic body radiotherapy (SBRT). A total of 126 patients with Stage I primary lung cancer treated with SBRT, who had undergone follow-up computed tomography (CT) at least 12 months after SBRT and who had no previous overlapping radiation exposure were included in the study. We used the Mantel–Haenszel method and multiple logistic regression analysis to compare risk factors. We analyzed D(0.5 cm3) (minimum absolute dose received by a 0.5-cm3 volume) and identified each rib that received a biologically effective dose (BED) (BED3, using the linear–quadratic (LQ) formulation assuming an α/β = 3) of at least 50 Gy. Of the 126 patients, 46 (37%) suffered a total of 77 RIRFs. The median interval from SBRT to RIRF detection was 15 months (range, 3–56 months). The 3-year cumulative probabilities were 45% (95% CI, 34–56%) and 3% (95% CI, 0–6%), for Grades 1 and 2 RIRFs, respectively. Multivariate analysis showed that tumor location was a statistically significant risk factor for the development of Grade 1 RIRFs. Of the 77 RIRFs, 71 (92%) developed in the true ribs (ribs 1–7), and the remaining six developed in the false ribs (ribs 8–12). The BED3 associated with 10% and 50% probabilities of RIRF were 55 and 210 Gy to the true ribs and 240 and 260 Gy to the false ribs. We conclude that RIRFs develop more frequently in true ribs than in false ribs. PMID:25504640

  9. Flow and heat transfer investigation behind trapezoidal rib using PIV and LCT measurements

    NASA Astrophysics Data System (ADS)

    Ali, Md Shaukat; Tariq, Andallib; Gandhi, B. K.

    2013-05-01

    The present work is an experimental investigation inside a rectangular duct for flow behind a trapezoidal type of rib with chamfering angle α (toward the direction of flow) at different Reynolds numbers. Chamfering angle α has been varied in between 0° and 20° with an increment of 5° and subsequently detailed fluid flow and heat transfer experiments have been performed at four different Reynolds numbers, that is, 9,400, 27,120, 44,600, and 61,480 (based on hydraulic diameter of the duct). In order to investigate the detailed fluid flow and heat transfer characteristics together, a distinct experimental setup has been designed while using 2-D particle image velocimetry and liquid crystal thermography, respectively. Flow investigations have been restricted within the streamwise location of x/ e ≤ 11, while the region of interest for heat transfer measurement goes up to x/ e ≤ 50. The emphasis is toward assessing and analyzing the potential impact of varying chamfering angle over the flow structures, and its subsequent effect on far downstream heat transfer enhancement, as well as its role in obviating the hot spots in the adjacent vicinity behind the chamfered rib turbulators. Transient heat transfer investigation has been performed for evaluating the surface heat transfer enhancement. Results are documented in terms of stream traces, mean and rms velocity fields, streamwise Reynolds stresses and vorticity distribution, and surface and spanwise averaged augmentation Nusselt numbers. The reattachment length has been identified for all of the configurations, and the turbulent characteristics have been discussed in reference to the reattaching shearing layer and its potential impact on the size of the recirculation bubble for different configurations and conditions. The result showed the successful impact of changing the trapezoidal angle α by manipulating the small-scale vortices at the leeward corner of the rib which helps in obviating the hot spots

  10. Wastewater contaminant transport and treatment in a nutrient limited ribbed fen

    NASA Astrophysics Data System (ADS)

    McCarter, C. P. R.; Price, J. S.; Branfireun, B. A.

    2015-12-01

    To minimize the discharge of wastewater contaminants from remote northern communities and mining operations, fen peatlands in sub-arctic regions are used for tertiary wastewater treatment to detain, transform, and remove these contaminants. However, there is a limited understanding of contaminant transport and treatment in fen peatlands, particularly in sub-arctic Canada. To better characterize wastewater contaminant transport and treatment in these systems, approximately 44 m3 day-1 of simulated wastewater, concentrated custom-blend fertilizer (NO3-, PO33-, and SO42-) and Cl- diluted with water, was pumped into a small 0.5 ha sub-arctic ribbed fen continuously for 47 days (July 15th -August 31st 2014). Contaminant concentration of 3 similar ribbed fens varied between 0.0-3.0 mg L-1 over the study period (May - September 2014). An exponential increase in transmissivity (2.4 to 16.8 m2 day-1) as the water table rose (~0.16 m) increased the average linear groundwater velocity (0.5 to 3.4 m day-1) and resulted in rapid SO42- (0.8 m day-1) and Cl- (1.9 m day-1) transport. Notwithstanding the rapid transport of Cl-, diffusion into inactive pores still retarded Cl- transport by a factor of 1.8. Contrary to the rapid transport of SO42- and Cl-, the other contaminants were rapidly removed from the pore water (likely through biological uptake or adsorption) and minimal transport was observed (0.29 and 0.04 m day-1 for PO33- and NO3-, respectively). Northern ribbed fens have a large capacity to detain certain wastewater contaminants (e.g., NO3- and PO33-), yet allow rapid transport of others (e.g., SO42- and Cl-). Thus, these peatlands have the potential to significantly decrease wastewater contamination in northern aquatic environment by both biogeochemical and physical processes but careful management of the hydrology is required to prevent the release of mobile contaminants.

  11. Are isolated wetlands isolated?

    USGS Publications Warehouse

    Smith, Loren M.; Euliss, Ned H.; Haukos, David A.

    2011-01-01

    While federal regulations during the past 10 years have treated isolated wetlands as unconnected to aquatic resources protected by the Clean Water Act, they provide critical ecosystem services to society that extend well beyond their wetland boundaries. The authors offer well-documented examples from the scientific literature on some of the ecosystem services provided by isolated wetlands to society and other ecosystems.

  12. Sonographic measurement of the fetal rib cage perimeter to thoracic circumference ratio: application to prenatal diagnosis of skeletal dysplasias.

    PubMed

    Dugoff, L; Coffin, C T; Hobbins, J C

    1997-10-01

    The object of this study was to establish new normative data for the fetal rib cage perimeter to thoracic circumference ratio, and to evaluate the potential application of this measurement in the diagnosis of short rib and other skeletal dysplasias. Rib cage perimeter (RCP) and thoracic circumference (TC) were measured in a prospective, cross-sectional sample of 88 patients with normal pregnancies between 14 and 39 weeks of gestation. The RCP and TC were both measured in cross-section, at a level of the four-chamber view of the fetal heart. RCP and TC measurements were also obtained from eight cases known to have skeletal dysplasias. The mean (+/- SE) RCP:TC ratio in normal pregnancies, regardless of gestational age, was 0.670 +/- 0.004. In five of eight cases with skeletal dysplasias the RCP:TC ratio was significantly decreased, and in one case it was increased. The RCP:TC ratio in normal fetuses is independent of gestational age. In this small series the ratio was abnormal in fetuses with certain skeletal dysplasias, and particularly decreased in the fetus with a short rib-polydactyly syndrome. After further evaluation, this technique may prove to be of clinical significance in helping to diagnose skeletal dysplasias, particularly in cases where the gestational age is uncertain. PMID:9383879

  13. Analysis of fluid flow and heat transfer in a rib grit roughened surface solar air heater using CFD

    SciTech Connect

    Karmare, S.V.; Tikekar, A.N.

    2010-03-15

    This paper presents the study of fluid flow and heat transfer in a solar air heater by using Computational Fluid Dynamics (CFD) which reduces time and cost. Lower side of collector plate is made rough with metal ribs of circular, square and triangular cross-section, having 60 inclinations to the air flow. The grit rib elements are fixed on the surface in staggered manner to form defined grid. The system and operating parameters studied are: e/D{sub h} = 0.044, p/e = 17.5 and l/s = 1.72, for the Reynolds number range 3600-17,000. To validate CFD results, experimental investigations were carried out in the laboratory. It is found that experimental and CFD analysis results give the good agreement. The optimization of rib geometry and its angle of attack is also done. The square cross-section ribs with 58 angle of attack give maximum heat transfer. The percentage enhancement in the heat transfer for square plate over smooth surface is 30%. (author)

  14. Effect of finishing steers on different forages or high concentrate diet on rib composition, color, and palatability

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Angus-crossbred steers (n = 128) were used to determine the effects of forage species grazed in the last 41 d or high concentrate finishing on rib composition, color, and palatability of beef. Steers grazed mixed pastures (bluegrass/white clover) for 93 d and then grazed alfalfa (AL; n = 36), pearl ...

  15. The effect of expiratory rib cage compression before endotracheal suctioning on the vital signs in patients under mechanical ventilation

    PubMed Central

    Bousarri, Mitra Payami; Shirvani, Yadolah; Agha-Hassan-Kashani, Saeed; Nasab, Nouredin Mousavi

    2014-01-01

    Background: In patients undergoing mechanical ventilation, mucus production and secretion is high as a result of the endotracheal tube. Because endotracheal suction in these patients is essential, chest physiotherapy techniques such as expiratory rib cage compression before endotracheal suctioning can be used as a means to facilitate mobilizing and removing airway secretion and improving alveolar ventilation. As one of the complications of mechanical ventilation and endotracheal suctioning is decrease of cardiac output, this study was carried out to determine the effect of expiratory rib cage compression before endotracheal suctioning on the vital signs in patients under mechanical ventilation. Materials and Methods: This study was a randomized clinical trial with a crossover design. The study subjects included 50 mechanically ventilated patients, hospitalized in intensive care wards of Valiasr and Mousavi hospitals in Zanjan, Iran. Subjects were selected by consecutive sampling and randomly allocated to groups 1 and 2. The patients received endotracheal suctioning with or without rib cage compression, with a minimum of 3 h interval between the two interventions. Expiratory rib cage compression was performed for 5 min before endotracheal suctioning. Vital signs were measured 5 min before and 15 and 25 min after endotracheal suctioning. Data were recorded on a data recording sheet. Data were analyzed using paired t-tests. Results: There were statistically significant differences in the means of vital signs measured 5 min before with 15 and 25 min after endotracheal suctioning with rib cage compression (P < 0. 01). There was no significant difference in the means of diastolic pressure measured 25 min after with baseline in this stage). But on the reverse mode, there was a significant difference between the means of pulse and respiratory rate 15 min after endotracheal suctioning and the baseline values (P < 0.002). This effect continued up to 25 min after endotracheal

  16. Radiation-Induced Rib Fractures After Hypofractionated Stereotactic Body Radiation Therapy: Risk Factors and Dose-Volume Relationship

    SciTech Connect

    Asai, Kaori; Shioyama, Yoshiyuki; Nakamura, Katsumasa; Sasaki, Tomonari; Ohga, Saiji; Nonoshita, Takeshi; Yoshitake, Tadamasa; Ohnishi, Kayoko; Terashima, Kotaro; Matsumoto, Keiji; Hirata, Hideki; Honda, Hiroshi

    2012-11-01

    Purpose: The purpose of this study was to clarify the incidence, the clinical risk factors, and the dose-volume relationship of radiation-induced rib fracture (RIRF) after hypofractionated stereotactic body radiation therapy (SBRT). Methods and Materials: One hundred sixteen patients treated with SBRT for primary or metastatic lung cancer at our institution, with at least 6 months of follow-up and no previous overlapping radiation exposure, were included in this study. To determine the clinical risk factors associated with RIRF, correlations between the incidence of RIRF and the variables, including age, sex, diagnosis, gross tumor volume diameter, rib-tumor distance, and use of steroid administration, were analyzed. Dose-volume histogram analysis was also conducted. Regarding the maximum dose, V10, V20, V30, and V40 of the rib, and the incidences of RIRF were compared between the two groups divided by the cutoff value determined by the receiver operating characteristic curves. Results: One hundred sixteen patients and 374 ribs met the inclusion criteria. Among the 116 patients, 28 patients (46 ribs) experienced RIRF. The estimated incidence of rib fracture was 37.7% at 3 years. Limited distance from the rib to the tumor (<2.0 cm) was the only significant risk factor for RIRF (p = 0.0001). Among the dosimetric parameters used for receiver operating characteristic analysis, the maximum dose showed the highest area under the curve. The 3-year estimated risk of RIRF and the determined cutoff value were 45.8% vs. 1.4% (maximum dose, {>=}42.4 Gy or less), 51.6% vs. 2.0% (V40, {>=}0.29 cm{sup 3} or less), 45.8% vs. 2.2% (V30, {>=}1.35 cm{sup 3} or less), 42.0% vs. 8.5% (V20, {>=}3.62 cm{sup 3} or less), or 25.9% vs. 10.5% (V10, {>=}5.03 cm{sup 3} or less). Conclusions: The incidence of RIRF after hypofractionated SBRT is relatively high. The maximum dose and high-dose volume are strongly correlated with RIRF.

  17. Deep-subwavelength hybrid plasmonic waveguide with metal-semiconductor ribs for nanolaser applications

    NASA Astrophysics Data System (ADS)

    Li, Zhiquan; Piao, Ruiqi; Zhao, Jingjing; Meng, Xiaoyun; Li, Wenchao; Niu, Liyong; Gu, Erdan

    2015-12-01

    We propose a novel hybrid plasmonic waveguide with metal-semiconductor ribs. We investigated the modal properties of the proposed structure and the threshold property for plasmonic nanolaser applications by using the finite element method. The results reveal that the structure enables deep-subwavelength mode confinement with low propagation loss and low threshold. By optimizing the geometric parameters of the structure, the mode area can reach 0.000 29λ 2 with a threshold of 700.9/cm at the wavelength of 1.55 μm. Compared to the previously studied hybrid plasmonic waveguide, tighter mode confinement and lower propagation loss is simultaneously achieved for the structure with the same geometric parameters. The designed structure can be used as a low-threshold nanolaser and has promising potential for applications in active plasmonic systems and optoelectronic integrated circuits.

  18. Midfoot reconstruction with serratus anterior-rib osteomuscular free flap following oncological resection of synovial sarcoma.

    PubMed

    Battiston, Bruno; Artiaco, Stefano; Piana, Raimondo; Boux, Elena; Tos, Pierluigi

    2015-12-01

    During recent decades, the concept of surgical treatment of malignant bone and soft tissue sarcomas has evolved, with the aim of preserving limb function. In this paper we report a case of metatarsal reconstruction by means of serratus and rib free flap after excision of a synovial sarcoma located in the dorsal aspect of the midfoot. Five years after the operation, the patient was free from recurrence and recovered full foot function. Amputation has been widely used in the past and this procedure still remains a valuable option when limb salvage is not possible. Nevertheless, in selected cases, reconstruction by means of composite free flaps may be successfully used for limb preservation in the treatment of malignant foot tumors after surgical excision. PMID:25838161

  19. Promises and Challenges of Two-Step Targets for Production of Neutron-rich RIBs

    SciTech Connect

    Talbert, W.L.; Drake, D.M.; Hsu, H.-H.; Wilson, M.T.

    2003-08-26

    Development of a prototype two-step target to produce neutron-rich RIBs is presented, with particular emphasis on thermal analysis under high-power operation. The two-step target is an attractive concept for production of fission-product activities without interference by high-energy spallation reactions which occur in direct production targets. In this concept, a high-energy production beam interacts with a primary target of refractory metal, depositing beam energy in the primary target and producing low-energy neutrons that cause fissions in a surrounding secondary target of mixed UC2 and excess C. Thermal analysis of the composite target presents challenges in cooling the primary target while maintaining the secondary target at temperatures suitable for release of the fission products. The effects of fission energy deposition in the secondary target are discussed, along with the complexities resulting from the thermally insulating character of the secondary target material.

  20. Predator-prey interactions between blue crabs and ribbed mussels living in clumps

    NASA Astrophysics Data System (ADS)

    Lin, Junda

    1991-01-01

    Predator-prey interactions between blue crabs ( Callinectes sapidus) and ribbed mussels ( Geukensia demissa) were studied by manipulating different components of mussel clump structure in the laboratory to test their effects on the mussels' susceptibility to crab predation. Mussels with stronger attachment strength or those buried deeper in the sediment suffered lower mortality. Blue crabs showed no significant size selectivity when two size classes of mussles (30-40 and 50-60 mm in shell heights) were offered. When juvenile mussels were attached to adult conspecifics and completely buried in the centres of clumps as in the field, blue crabs did not actively search for them. The crabs, however, did consume juveniles as by-products when they preyed upon the adult mussels to which the juveniles were attached.

  1. A new concept Tandem thermal dissociator/electron impact ion source for RIB generation

    SciTech Connect

    Alton, G.D.; Williams, C.

    1995-12-31

    An innovative thermal dissociation/electron impact ionization positive ion source is presently under design at the Oak Ridge National Laboratory for potential use for generating RIBs at the Holifield Radioactive Ion Beam Facility (HRIBF). Because of the low probability of simultaneously dissociating and efficiently ionizing the individual atomic constituents with conventional, hot-cathode, electron-impact ion sources, the ion beams extracted from these sources often appear as a mixture of several molecular sideband beams. In this way, the intensity of the species of interest is diluted. We have conceived an Ion source that combines the excellent molecular dissociation properties of a thermal dissociator and the high efficiency characteristics of an electron impact ionization source. If the concept proves to be a viable option, the source will be used as a complement to the electron beam plasma ion sources already in use at the HRIBF. The design features and principles of operation of the source are described in this article.

  2. Genetic analysis of jumbled spine and ribs (Jsr) mutation affecting the vertebral development in mice.

    PubMed

    Okano, Shinya; Asano, Atsushi; Kon, Yasuhiro; Miyoshi, Hiroyuki; Watanabe, Tomomasa

    2002-10-01

    The jumbled spine and ribs (Jsr) mouse was derived from a spontaneous mutation. As the phenotype, a shortened trunk and kinky tail are characteristic Jsr traits. In this study, on high resolution mapping it was found that Lunatic fringe (Lfng) mapped at the same position as Jsr. Lfng was identified as the candidate gene for Jsr, but sequence analysis of this gene revealed no substitution in the coding region of cDNA. Therefore, we adopted the strategy of positional cloning for Jsr using a mouse bacterial artificial chromosome (BAC) library. A BAC contig was constructed from three BAC clones showing positive signals of Lfng and 11MMHAP75FRD8.seq near the Jsr locus on chromosome 5. Based on the genetic mapping of both T7 and sp6 ends of a clone of BAC382-O-7 (BAC382), the Jsr gene was considered to exist in BAC382 and to be positioned near the sp6 side. PMID:12392169

  3. Clustered ribbed-nanoneedle structured copper surfaces with high-efficiency dropwise condensation heat transfer performance.

    PubMed

    Zhu, Jie; Luo, Yuting; Tian, Jian; Li, Juan; Gao, Xuefeng

    2015-05-27

    We report that the dropwise condensation heat transfer (DCHT) effectiveness of copper surfaces can be dramatically enhanced by in situ grown clustered ribbed-nanoneedles. Combined experiments and theoretical analyses reveal that, due to the microscopically rugged and low-adhesive nature of building blocks, the nanosamples can not only realize high-density nucleation but constrain growing condensates into suspended microdrops via the self-transport and/or self-expansion mode for subsequently self-propelled jumping, powered by coalescence-released excess surface energy. Consequently, our nanosample exhibits over 125% enhancement in DCHT coefficient. This work helps develop advanced heat-transfer materials and devices for efficient thermal management and energy utilization. PMID:25966966

  4. Cardiopulmonary resuscitation (CPR)-related posterior rib fractures in neonates and infants following recommended changes in CPR techniques.

    PubMed

    Franke, I; Pingen, A; Schiffmann, H; Vogel, M; Vlajnic, D; Ganschow, R; Born, M

    2014-07-01

    Posterior rib fractures are highly indicative of non-accidental trauma (NAT) in infants. Since 2000, the "two-thumbs" technique for cardiopulmonary resuscitation (CPR) of newborns and infants has been recommended by the American Heart Association (AHA). This technique is similar to the grip on an infant's thorax while shaking. Is it possible that posterior rib fractures in newborns and infants could be caused by the "two-thumbs" technique? Using computerized databases from three German children's hospitals, we identified all infants less than 12 months old who underwent professional CPR within a 10-year period. We included all infants with anterior-posterior chest radiographs taken after CPR. Exclusion criteria were sternotomy, osteopenia, various other bone diseases and NAT. The radiographs were independently reviewed by the Chief of Pediatric Radiology (MB) and a Senior Pediatrician, Head of the local Child Protection Team (IF). Eighty infants with 546 chest radiographs were identified, and 50 of those infants underwent CPR immediately after birth. Data concerning the length of CPR was available for 41 infants. The mean length of CPR was 11min (range: 1-180min, median: 3min). On average, there were seven radiographs per infant. A total of 39 infants had a follow-up radiograph after at least 10 days. No rib fracture was visible on any chest X-ray. The results of this study suggest rib fracture after the use of the "two-thumbs" CPR technique is uncommon. Thus, there should be careful consideration of abuse when these fractures are identified, regardless of whether CPR was performed and what technique used. The discovery of rib fractures in an infant who has undergone CPR without underlying bone disease or major trauma warrants a full child protection investigation. PMID:24636360

  5. Experimental determination of average turbulent heat transfer and friction factor in stator internal rib-roughened cooling channels.

    PubMed

    Battisti, L; Baggio, P

    2001-05-01

    In gas turbine cooling design, techniques for heat extraction from the surfaces exposed to the hot stream are based on the increase of the inner heat transfer areas and on the promotion of the turbulence of the cooling flow. This is currently obtained by casting periodic ribs on one or more sides of the serpentine passages into the core of the blade. Fluid dynamic and thermal behaviour of the cooling flow have been extensively investigated by means of experimental facilities and many papers dealing with this subject have appeared in the latest years. The evaluation of the average value of the heat transfer coefficient most of the time is inferred from local measurements obtained by various experimental techniques. Moreover the great majority of these studies are not concerned with the overall average heat transfer coefficient for the combined ribs and region between them, but do focus just on one of them. This paper presents an attempt to collect information about the average Nusselt number inside a straight ribbed duct. Series of measurements have been performed in steady state eliminating the error sources inherently connected with transient methods. A low speed wind tunnel, operating in steady state flow, has been built to simulate the actual flow condition occurring in a rectilinear blade cooling channel. A straight square channel with 20 transverse ribs on two sides has been tested for Re of about 3 x 10(4), 4.5 x 10(4) and 6 x 10(4). The ribbed wall test section is electrically heated and the heat removed by a stationary flow of known thermal and fluid dynamic characteristics. PMID:11460662

  6. Effects of follower load and rib cage on intervertebral disc pressure and sagittal plane curvature in static tests of cadaveric thoracic spines.

    PubMed

    Anderson, Dennis E; Mannen, Erin M; Sis, Hadley L; Wong, Benjamin M; Cadel, Eileen S; Friis, Elizabeth A; Bouxsein, Mary L

    2016-05-01

    The clinical relevance of mechanical testing studies of cadaveric human thoracic spines could be enhanced by using follower preload techniques, by including the intact rib cage, and by measuring thoracic intervertebral disc pressures, but studies to date have not incorporated all of these components simultaneously. Thus, this study aimed to implement a follower preload in the thoracic spine with intact rib cage, and examine the effects of follower load, rib cage stiffening and rib cage removal on intervertebral disc pressures and sagittal plane curvatures in unconstrained static conditions. Intervertebral disc pressures increased linearly with follower load magnitude. The effect of the rib cage on disc pressures in static conditions remains unclear because testing order likely confounded the results. Disc pressures compared well with previous reports in vitro, and comparison with in vivo values suggests the use of a follower load of about 400N to approximate loading in upright standing. Follower load had no effect on sagittal plane spine curvature overall, suggesting successful application of the technique, although increased flexion in the upper spine and reduced flexion in the lower spine suggest that the follower load path was not optimized. Rib cage stiffening and removal both increased overall spine flexion slightly, although with differing effects at specific spinal locations. Overall, the approaches demonstrated here will support the use of follower preloads, intact rib cage, and disc pressure measurements to enhance the clinical relevance of future studies of the thoracic spine. PMID:26944690

  7. Internal rib structure can be predicted using mathematical models: An anatomic study comparing the chest to a shell dome with application to understanding fractures.

    PubMed

    Casha, Aaron R; Camilleri, Liberato; Manché, Alexander; Gatt, Ruben; Attard, Daphne; Gauci, Marilyn; Camilleri-Podesta, Marie-Therese; Mcdonald, Stuart; Grima, Joseph N

    2015-11-01

    The human rib cage resembles a masonry dome in shape. Masonry domes have a particular construction that mimics stress distribution. Rib cortical thickness and bone density were analyzed to determine whether the morphology of the rib cage is sufficiently similar to a shell dome for internal rib structure to be predicted mathematically. A finite element analysis (FEA) simulation was used to measure stresses on the internal and external surfaces of a chest-shaped dome. Inner and outer rib cortical thickness and bone density were measured in the mid-axillary lines of seven cadaveric rib cages using computerized tomography scanning. Paired t tests and Pearson correlation were used to relate cortical thickness and bone density to stress. FEA modeling showed that the stress was 82% higher on the internal than the external surface, with a gradual decrease in internal and external wall stresses from the base to the apex. The inner cortex was more radio-dense, P < 0.001, and thicker, P < 0.001, than the outer cortex. Inner cortical thickness was related to internal stress, r = 0.94, P < 0.001, inner cortical bone density to internal stress, r = 0.87, P = 0.003, and outer cortical thickness to external stress, r = 0.65, P = 0.035. Mathematical models were developed relating internal and external cortical thicknesses and bone densities to rib level. The internal anatomical features of ribs, including the inner and outer cortical thicknesses and bone densities, are similar to the stress distribution in dome-shaped structures modeled using FEA computer simulations of a thick-walled dome pressure vessel. Fixation of rib fractures should include the stronger internal cortex. PMID:26297570

  8. An Insight to the Modeling of 1 × 1 Rib Loop Formation Process on Circular Weft Knitting Machine using Computer

    NASA Astrophysics Data System (ADS)

    Ray, Sadhan Chandra

    2015-10-01

    The mechanics of single jersey loop formation is well-reported is literature. However, as the concept of any model of double jersey loop formation process is not available in accessible international literature. Therefore, it was planned to develop a model of 1 × 1 rib loop formation process on dial and cylinder machine using computer so that the influence of various input variables on the final loop length as well on the profile of tension on the yarn inside Knitting Zone (KZ) can be understood. The model provides an insight into the mechanics of 1 × 1 rib loop formation system on dial and cylinder machine. Besides, the degree of agreement between predicted and measured values of loop length and cam forces as well as theoretical analysis of the model have justified the acceptability of the model.

  9. Bilateral first rib anomalous articulations with pseudarthroses mimicking healing fractures in an infant with abusive head injury.

    PubMed

    Pasquale-Styles, Melissa A; Crowder, Christian M; Fridie, Jeannette; Milla, Sarah S

    2014-11-01

    Bilateral symmetric bone nodules were observed in the anterolateral first ribs of an infant with shaking injuries at autopsy. The location prompted diagnostic considerations of healing fractures versus anomalous articulations with pseudarthroses. The forensic pathologist worked with forensic anthropologists and pediatric radiologists to evaluate autopsy findings and compare premortem and postmortem X-rays. Gross examination of the bones by the pathologist and anthropologists confirmed bilateral, callus-like bone nodules in first-rib locations associated with pseudarthroses. Histologic examination of one of the bones further showed features most consistent with pseudarthrosis, not a healing fracture. Radiologists then compared multiple premortem and postmortem radiographs that showed no remodeling of the bone over a 2-week interval between the time of injury and death, which would be unexpected for a healing fracture in an infant. This multidisciplinary approach resulted in the appropriate diagnosis of pseudarthroses due to anomalous articulations, an uncommon finding in forensic pathology. PMID:25382601

  10. Chest wall segmentation in automated 3D breast ultrasound using rib shadow enhancement and multi-plane cumulative probability enhanced map

    NASA Astrophysics Data System (ADS)

    Kim, Hyeonjin; Kim, Hannah; Hong, Helen

    2015-03-01

    We propose an automatic segmentation method of chest wall in 3D ABUS images using rib shadow enhancement and multi-planar cumulative probability enhanced map. For the identification of individual dark rib shadows, each rib shadow is enhanced using intensity transfer function and 3D sheet-like enhancement filtering. Then, wrongly enhanced intercostal regions and small fatty tissues are removed using coronal and sagittal cumulative probability enhanced maps. The large fatty tissues with globular and sheet-like shapes at the top of rib shadow are removed using shape and orientation analysis based on moment matrix. Detected chest walls are connected with cubic B-spline interpolation. Experimental results show that the Dice similarity coefficient of proposed method as comparison with two manually outlining results provides over 90% in average.

  11. The Expansion of the Pulmonary Rib Cage during Breath Stacking Is Influenced by Age in Obese Women

    PubMed Central

    Barcelar, Jacqueline de Melo; Aliverti, Andrea; Rattes, Catarina; Ximenes, Maria Eduarda; Campos, Shirley Lima; Brandão, Daniella Cunha; Fregonezi, Guilherme; de Andrade, Armèle Dornelas

    2014-01-01

    Objective To analyze in obese women the acute effects of the breath stacking technique on thoraco-abdominal expansion. Design and Methods Nineteen obese women (BMI≥30 kg/m2) were evaluated by anthropometry, spirometry and maximal respiratory muscle pressures and successively analyzed by Opto-Electronic Plethysmography and a Wright respirometer during quiet breathing and breath stacking maneuvers and compared with a group of 15 normal-weighted healthy women. The acute effects of the maneuvers were assessed in terms of total and compartmental chest wall volumes at baseline, end of the breath stacking maneuver and after the maneuver. Obese subjects were successively classified into two groups, accordingly to the response during the maneuver, group 1 = prevalent rib cage or group 2 = abdominal expansion. Results Age was significantly lower in group 1 than group 2. When considering the two obese groups, FEV1 was lower and minute ventilation was higher only in group 2 compared to controls group. During breath stacking, inspiratory capacity was significant differences in obese subjects with a smaller expansion of the pulmonary rib cage and a greater expansion of the abdomen compared to controls and also between groups 1 and 2. A significant inverse linear relationship was found between age and inspiratory capacity of the pulmonary rib cage but not of the abdomen. Conclusions In obese women the maximal expansion of the rib cage and abdomen is influenced by age and breath stacking maneuver could be a possible therapy for preventing respiratory complications. PMID:25372469

  12. Predicting rib fracture risk with whole-body finite element models: development and preliminary evaluation of a probabilistic analytical framework.

    PubMed

    Forman, Jason L; Kent, Richard W; Mroz, Krystoffer; Pipkorn, Bengt; Bostrom, Ola; Segui-Gomez, Maria

    2012-01-01

    This study sought to develop a strain-based probabilistic method to predict rib fracture risk with whole-body finite element (FE) models, and to describe a method to combine the results with collision exposure information to predict injury risk and potential intervention effectiveness in the field. An age-adjusted ultimate strain distribution was used to estimate local rib fracture probabilities within an FE model. These local probabilities were combined to predict injury risk and severity within the whole ribcage. The ultimate strain distribution was developed from a literature dataset of 133 tests. Frontal collision simulations were performed with the THUMS (Total HUman Model for Safety) model with four levels of delta-V and two restraints: a standard 3-point belt and a progressive 3.5-7 kN force-limited, pretensioned (FL+PT) belt. The results of three simulations (29 km/h standard, 48 km/h standard, and 48 km/h FL+PT) were compared to matched cadaver sled tests. The numbers of fractures predicted for the comparison cases were consistent with those observed experimentally. Combining these results with field exposure informantion (ΔV, NASS-CDS 1992-2002) suggests a 8.9% probability of incurring AIS3+ rib fractures for a 60 year-old restrained by a standard belt in a tow-away frontal collision with this restraint, vehicle, and occupant configuration, compared to 4.6% for the FL+PT belt. This is the first study to describe a probabilistic framework to predict rib fracture risk based on strains observed in human-body FE models. Using this analytical framework, future efforts may incorporate additional subject or collision factors for multi-variable probabilistic injury prediction. PMID:23169122

  13. Predicting Rib Fracture Risk With Whole-Body Finite Element Models: Development and Preliminary Evaluation of a Probabilistic Analytical Framework

    PubMed Central

    Forman, Jason L.; Kent, Richard W.; Mroz, Krystoffer; Pipkorn, Bengt; Bostrom, Ola; Segui-Gomez, Maria

    2012-01-01

    This study sought to develop a strain-based probabilistic method to predict rib fracture risk with whole-body finite element (FE) models, and to describe a method to combine the results with collision exposure information to predict injury risk and potential intervention effectiveness in the field. An age-adjusted ultimate strain distribution was used to estimate local rib fracture probabilities within an FE model. These local probabilities were combined to predict injury risk and severity within the whole ribcage. The ultimate strain distribution was developed from a literature dataset of 133 tests. Frontal collision simulations were performed with the THUMS (Total HUman Model for Safety) model with four levels of delta-V and two restraints: a standard 3-point belt and a progressive 3.5–7 kN force-limited, pretensioned (FL+PT) belt. The results of three simulations (29 km/h standard, 48 km/h standard, and 48 km/h FL+PT) were compared to matched cadaver sled tests. The numbers of fractures predicted for the comparison cases were consistent with those observed experimentally. Combining these results with field exposure informantion (ΔV, NASS-CDS 1992–2002) suggests a 8.9% probability of incurring AIS3+ rib fractures for a 60 year-old restrained by a standard belt in a tow-away frontal collision with this restraint, vehicle, and occupant configuration, compared to 4.6% for the FL+PT belt. This is the first study to describe a probabilistic framework to predict rib fracture risk based on strains observed in human-body FE models. Using this analytical framework, future efforts may incorporate additional subject or collision factors for multi-variable probabilistic injury prediction. PMID:23169122

  14. Pressure distribution on wing ribs of the VE-7 and TS airplanes in flight Part II : pull-ups

    NASA Technical Reports Server (NTRS)

    Rhode, R V

    1928-01-01

    This paper is the second of a series of notes, each of which presents the complete results of pressure distribution tests made at Langley Field by the National Advisory Committee for Aeronautics, on wing and tail ribs of the VE-7 and TS airplanes for a particular maneuver of flight. The results for pull-ups are presented in the form of curves which show the variation of pressure distribution, total loads, normal acceleration and center of pressure with respect to time.

  15. Local heat/mass transfer and pressure drop in a two-pass rib-roughened channel for turbine airfoil cooling

    NASA Technical Reports Server (NTRS)

    Han, J. C.; Chandra, P. R.

    1987-01-01

    The heat transfer characteristics of turbulent air flow in a multipass channel were studied via the naphthalene sublimation technique. The naphthalene-coated test section, consisting of two straight, square channels joined by a 180 deg turn, resembled the internal cooling passages of gas turbine airfoils. The top and bottom surfaces of the test channel were roughened by rib turbulators. The rib height-to-hydraulic diameter ratio (e/D) were 0.063 and 0.094, and the rib pitch-to-height ratio (P/e) were 10 and 20. The local heat/mass transfer coefficients on the roughened top wall and on the smooth divider and side walls of the test channel were determined for three Reynolds numbers of 15, 30, and 60, thousand, and for three angles of attack (alpha) of 90, 60, and 45 deg. Results showed that the local Sherwood numbers on the ribbed walls were 1.5 to 6.5 times those for a fully developed flow in a smooth square duct. The average ribbed-wall Sherwood numbers were 2.5 to 3.5 times higher than the fully developed values, depending on the rib angle of attack and the Reynolds number. The results also indicated that, before the turn, the heat/mass transfer coefficients in the cases of alpha = 60 and 45 deg were higher than those in the case of alpha=90 deg. However, after the turn, the heat/mass transfer coefficients in the oblique-rib cases were lower than those in the transverse rib case. Correlations for the average Sherwood number ratios for individual channel surfaces and for the overall Sherwood number ratios are reported. Correlations for the fully developed friction factors and for the loss coefficients are also provided.

  16. Comparison of PCB and trace metal bioaccumulation in the blue mussel, Mytilus edulis, and the ribbed mussel, Modiolus demissus, in New Bedford Harbor, Massachusetts

    SciTech Connect

    Nelson, W.G.; Bergen, B.J.; Cobb, D.J.

    1995-03-01

    The accumulation of PCBs and trace metals was compared at 14-d intervals between two filter-feeding bivalves, the blue mussel, Mytilus edulis, and the ribbed mussel, Modiolus demissus, after deployment in New Bedford Harbor, Massachusetts, for up to 56 d. Contaminant uptake in deployed organisms also was compared with indigenous ribbed mussels. Significant mortality occurred in blue mussels after 28 d, when water temperatures exceeded 25 C. Therefore, tissue-residue comparisons between species are presented only up to day 28, while those between deployed and indigenous ribbed mussels continue to day 56. Results indicated that total PCB tissue residues and congener distributions were not statistically different in the two mussel species on day 28. Total PCB concentrations in both deployed mussel species reached approximately 30 {mu}g g{sup {minus}1} dry weight by day 28. Additionally, total PCB concentrations and congener distributions in the deployed ribbed mussels were not statistically different from the indigenous ribbed mussels on day 28, demonstrating that steady state was attained within 28 d. With respect to metal uptake, no single accumulation pattern occurred for the eight metals quantified. After 28 d, lead, cadmium, and iron concentrations in deployed blue and ribbed mussels were statistically similar. However, nickel and zinc accumulations were significantly greater in the blue mussels, and copper, chromium, and manganese were accumulated to significantly higher concentrations in the ribbed mussels. The comparison between the ribbed mussels indicated that cadmium and lead concentrations were significantly higher in indigenous than in deployed mussels after 28 d.

  17. Proper Orthogonal Decomposition Analysis of Turbulent Jet Impingement on Rib-roughened Surface

    NASA Astrophysics Data System (ADS)

    Lam, Prasanth Anand Kumar; Karaiyan, Arul Prakash; Thermo-Fluid Dynamics Laboratory Team

    2015-11-01

    A Proper Orthogonal Decomposition (POD) analysis on turbulent flow dynamics of confined slot jet impinging on rib-roughened surface is numerically investigated. The data for POD analysis has been obtained by solving mass, momentum and energy equations in Cartesian framework using Streamline Upwind/Petrov-Galerkin Finite element method. Further, turbulent kinetic energy (k) and its dissipation rate (ɛ) are modeled using standard k- ɛ turbulence model with standard wall functions. POD is applied to computational data for a wide range of Reynolds number (Re) = 5000 - 30000 and non-dimensional channel height (H/L) = 0.5 - 4.0 to reveal large scale vortical structures in the flow field. The simulated results demonstrate a better understanding on effect of turbulence and its influence on individual vortical structures for enhancement of heat transfer. The enhancement of heat transfer in stagnation region due to combined effect of oscillation in impingement position caused by large vortical structures and strong acceleration of fluid during impingement is quantified. Furthermore, non-dimensional correlations have been derived for pressure drop and Surface averaged Nusselt number.

  18. Population ecology of the gulf ribbed mussel across a salinity gradient: recruitment, growth and density

    USGS Publications Warehouse

    Honig, Aaron; Supan, John; LaPeyre, Megan K.

    2015-01-01

    Benthic intertidal bivalves play an essential role in estuarine ecosystems by contributing to habitat provision, water filtration, and promoting productivity. As such, changes that impact population distributions and persistence of local bivalve populations may have large ecosystem level consequences. Recruitment, growth, mortality, population size structure and density of the gulf coast ribbed mussel, Geukensia granosissima, were examined across a salinity gradient in southeastern Louisiana. Data were collected along 100-m transects at interior and edge marsh plots located at duplicate sites in upper (salinity ~4 psu), central (salinity ~8 psu) and lower (salinity ~15 psu) Barataria Bay, Louisiana, U.S.A. Growth, mortality and recruitment were measured in established plots from April through November 2012. Mussel densities were greatest within the middle bay (salinity ~8) regardless of flooding regime, but strongly associated with highest stem densities of Juncus roemerianus vegetation. Mussel recruitment, growth, size and survival were significantly higher at mid and high salinity marsh edge sites as compared to all interior marsh and low salinity sites. The observed patterns of density, growth and mortality in Barataria Bay may reflect detrital food resource availability, host vegetation community distribution along the salinity gradient, salinity tolerance of the mussel, and reduced predation at higher salinity edge sites.

  19. Multiple severe stab wounds to chest with cuts to the ribs. Suicide or homicide?

    PubMed

    Kaliszan, Michał

    2011-01-01

    This paper presents the case of a 36-year-old man found dead in a forest near his home with multiple stab wounds on the chest and abdomen, while the chest wounds penetrated deep into the left pleural cavity and the lung parenchyma, completely cutting through the bone sections of four ribs along the channels of the wounds. In addition, a kitchen knife dug into the ground was found in the immediate vicinity of the corpse. The deceased was wearing a T-shirt with numerous clearly visible holes in places corresponding to the wounds and quite a large tear at the bottom. The post-mortem revealed 19 distinct wounds of the chest as well as a dozen or so superficial marks of cuts or pricks with a pointed tool on the torso. The findings of the police investigation suggested that shortly before death the man was in a bad mood and he had been telling his friends to prepare for his funeral, which was supposed to point to suicidal tendencies. Could, however, such numerous and heavy bodily injuries have been self-inflicted and would such a wounded person still be able to dig a knife into hard forest bed? If yes, in this case we are most probably dealing with aggressive self-destruction, a type of behavior sometimes observed in people suffering from serious mental disorders. PMID:21216377

  20. Design of the IXO optics based on thin glass plates connected by reinforcing ribs

    NASA Astrophysics Data System (ADS)

    Parodi, G.; Martelli, F.; Basso, S.; Citterio, O.; Civitani, M.; Conconi, P.; Ghigo, M.; Pareschi, G.; Zambra, A.

    2011-09-01

    Effective area requirements for the large X-ray mirror of the International X-ray Observatory (IXO) are about 3 m2 at 1keV, 0.65 m2 at 6 keV and 150 cm2 at 30 keV. Because of its large dimension, the telescope cannot be realized as a monolithic structure but rather it requires the integration and assembly in the telescope optical bench of a number of basic module units, called X-ray Optical Unit (XOU). We are currently studying a method for the production of these basic units that is based on the slumping technology for the production of thin glass segmented mirrors. It foresees the implementation of a stacking integration concept based on the use of reinforcing ribs connecting the glass segments in order to create very stiff structures. This paper reports on the last design of the single optical module and describe the results of FEM analyses that show how it is possible to use an innovative approach to the integration of the slumped glass foils.

  1. A High-Temperature, "Volume-Type" ECR Ion Source for RIB Generation

    SciTech Connect

    Alton, G.D.; Liu, Y.; Reed, C.A.; Williams, C.; Zhang, T.

    1999-03-29

    A high temperature, low-charge-state, "volume-type" source has been designed for use in the nuclear physics and nuclear astrophysics research radioactive ion beam (RIB) programs at the Holifield Radioactive Ion beam Facility (HRIBF). The source utilizes electromagnetic coils to generate a large and uniformly distributed central magnetic field with magnitude (875 G) chosen to be in electron-cyclotron-resonance (ECR) with single- frequency (2.45 GHz) microwave radiation. Among the features of the source includti a variable mirror-ratio at ion extraction as required for optimizing low-charge state ion beam generation, a right-hand, circularly-polarized RF injection system to overcome the relatively-low, cutoff-density, (nC - 7.4x10'0/cm3) associated with the use of 2.45 GHz microwave radiatiom, and a high temperature, Ir- or Re-coated-Ta plasma chamber to reduce the residence times of radioactive species that are adsorbed on the walls of the chamber. No provisions are made for radial plasma confinement due to the sensitivity of permanent magnets to degradation by the huge fluxes of neutrons incumbent during target irradiation, routinely used for this purpose. Aspects of the design features of the source are described in this report.

  2. Comparative Chemistry of Aspergillus oryzae (RIB40) and A. flavus (NRRL 3357)

    PubMed Central

    Rank, Christian; Klejnstrup, Marie Louise; Petersen, Lene Maj; Kildgaard, Sara; Frisvad, Jens Christian; Gotfredsen, Charlotte Held; Larsen, Thomas Ostenfeld

    2012-01-01

    Aspergillus oryzae and A. flavus are important species in industrial biotechnology and food safety and have been some of the first aspergilli to be fully genome sequenced. Bioinformatic analysis has revealed 99.5% gene homology between the two species pointing towards a large coherence in the secondary metabolite production. In this study we report on the first comparison of secondary metabolite production between the full genome sequenced strains of A. oryzae (RIB40) and A. flavus (NRRL 3357). Surprisingly, the overall chemical profiles of the two strains were mostly very different across 15 growth conditions. Contrary to previous studies we found the aflatrem precursor 13-desoxypaxilline to be a major metabolite from A. oryzae under certain growth conditions. For the first time, we additionally report A. oryzae to produce parasiticolide A and two new analogues hereof, along with four new alkaloids related to the A. flavus metabolites ditryptophenalines and miyakamides. Generally the secondary metabolite capability of A. oryzae presents several novel end products likely to result from the domestication process from A. flavus. PMID:24957367

  3. Porous Polyethylene Implant and Rib Cartilage in Ear Reconstruction: A Comparison.

    PubMed

    Hamzavi, Sasan

    2015-12-01

    Auricular reconstruction, known as the "surgical art," is one of the most difficult and complex surgeries in medicine. There are two different techniques that involve either the use of artificial material like porous polyethylene (PE) or the patient's own rib cartilage graft. The patient's indication, age, conditions requiring previous failed surgeries, and the surgeon's skill in creating the frame are the most important factors in the choice of technique. Both methods are performed in our clinic in Vienna. We experienced more complications in the early cases using PE due to surgical inexperience. The advantages of PE, such as the fact that it is a single-stage surgery, favorable aesthetic appearance (definition and projection), and the possibility of combining the reconstruction with bone conduction devices or active middle ear implants and performing in older patients, can be compared with its disadvantages, such as greater complications. Both techniques require the acquisition of considerable skill and tricks, and for this reason it is important that a skilled surgeon who has mastered these auricular reconstruction skills is available to teach the next generation. PMID:26667636

  4. The temperature of cremation and its effect on the microstructure of the human rib compact bone.

    PubMed

    Absolonová, Karolina; Dobisiková, Miluse; Beran, Michal; Zocová, Jarmila; Velemínský, Petr

    2012-01-01

    The presented study deals with the effect of the cremation temperature on the microstructure and morphology of the human compact bone. The biological material consisted of samples from ribs of recent Central European origin belonging to individuals of known age, sex and cause of death. Each bone sample was divided into several sections. One section remained unburned and the rest were burned at 700, 800 and 1000 degrees C. A few samples were burned also at the temperature of 600 degrees C. The undecalcified unstained ground cross-sections were made from burned and unburned bones; photographed and analysed using the SigmaScan Pro 5 programme. During burning, both the macroscopic and microscopic dimensions of the bone shrink, including the measures of the individual microstructures. The percentual representation of the area of individual microstructures on the area of the cross-section decreases. The number of individual microstructures per mm2 of the compact bone cross-section increases. Most microstructural variables demonstrated statistically significant differences at the individual temperatures of cremation. The burned bones showed a large scale of the colours, especially at 700 degrees C. PMID:23350156

  5. A combination thermal dissociation/electron impact ionization source for RIB generation

    SciTech Connect

    Alton, G.D.; Cui, B.; Welton, R.F.

    1996-12-31

    The flourishing interest in radioactive ion beams (RIBs) with intensities adequate for astrophysics and nuclear physics research place a premium on targets that will swiftly release trace amounts of short lived radio-nuclei in the presence of bulk quantities of target material and ion sources that have the capability of efficiently ionizing the release products. Because of the low probability of simultaneously dissociating and efficiently ionizing the individual atomic constituents of molecules containing the element of interest with conventional, hot-cathode, electron-impact ion sources, the species of interest is often distributed in several mass channels in the form of molecular sideband beams and, consequently, the intensity is diluted. The authors have conceived an ion source that combines the excellent molecular dissociation properties of a thermal dissociator and the high efficiency characteristics of an electron impact ionization source to address these problems. If the concept proves to be a viable option, the source will be used as a complement to the electron beam plasma ion sources already in use at the HRIBF. The design features and principles of operation of the source are described in this article.

  6. Nuss procedure for surgical stabilization of flail chest with horizontal sternal body fracture and multiple bilateral rib fractures

    PubMed Central

    Lee, Sung Kwang

    2016-01-01

    Flail chest is a life-threatening situation that paradoxical movement of the thoracic cage was caused by multiply fractured ribs in two different planes, or a sternal fracture, or a combination of the two. The methods to achieve stability of the chest wall are controversy between surgical fixation and mechanical ventilation. We report a case of a 33-year-old man who fell from a high place with fail chest due to multiple rib fractures bilaterally and horizontal sternal fracture. The conventional surgical stabilization using metal plates by access to the front of the sternum could not provide stability of the flail segment because the fracture surface was obliquely upward and there were multiple bilateral rib fractures adjacent the sternum. The Nuss procedure was performed for supporting the flail segment from the back. Flail chest was resolved immediately after the surgery. The patient was weaned from the mechanical ventilation on third postoperative day successfully and was ultimately discharged without any complications. PMID:27293864

  7. Partial costectomy for tracheal collapse and stenosis associated with perinatal rib fracture in three Japanese Black calves.

    PubMed

    Hidaka, Yuichi; Hagio, Mitsuyoshi; Kashiba, Ichiro; Ando, Kei; Otani, Yuki; Satoh, Hiroyuki; Konishi, Yuko; Tsuzuki, Nao; Hokamura, Junichi; Kajisa, Makoto; Wada, Mie; Kirino, Yumi; Asanuma, Taketoshi

    2016-04-01

    2.3-month-old (Case 1), one-month-old (Case 2) and 6-month-old (Case 3), Japanese Black calves presented with mild to severe wheezing. All calves had histories of dystocia at birth with breech presentation. Physical examination, thoracic radiography, endoscopy or computed tomography indicated wheezing associated with tracheal collapse and stenosis caused by perinatal rib fractures. Partial resection of the fractured first and second ribs was performed on all calves. The respiration in Cases 1 and 2 immediately improved after the surgery, while Case 3 required two weeks to improve. Cases 1 and 3 grew up healthy and were sold at auction, but Case 2 had a recurrence of wheezing at three months post-discharge and showed growth retarding. Partial costectomy may be an effective solution for control of respiration, however, further cases are required to discuss the criteria for surgical management and to obtain favorable postoperative prognosis in calves with tracheal collapse and stenosis caused by perinatal rib fractures. PMID:26522686

  8. Experimental Heat Transfer and Bulk Air Temperature Measurements for a Multipass Internal Cooling Model with Ribs and Bleed

    NASA Technical Reports Server (NTRS)

    Thurman, Douglas; Poinsatte, Philip

    2001-01-01

    An experimental study was made to obtain heat transfer and air temperature data for a simple three-leg serpentine test section that simulates a turbine blade internal cooling passage with trip strips and bleed holes. The objectives were to investigate the interaction of ribs and various bleed conditions on internal cooling and to gain a better understanding of bulk air temperature in an internal passage. Steady-state heat transfer measurements were obtained using a transient technique with thermochromic liquid crystals. Trip strips were attached to one wall of the test section and were located either between or near the bleed holes. The bleed holes, used for film cooling, were metered to simulate the effect of external pressure on the turbine blade. Heat transfer enhancement was found to be greater for ribs near bleed holes compared to ribs between holes, and both configurations were affected slightly by bleed rates upstream. Air temperature measurements were taken at discrete locations along one leg of the model. Average bulk air temperatures were found to remain fairly constant along one leg of the model.

  9. Experimental Heat Transfer and Bulk Air Temperature Measurements for a Multipass Internal Cooling Model with Ribs and Bleed

    NASA Technical Reports Server (NTRS)

    Thurman, Douglas; Poinsatte, Philip

    2000-01-01

    An experimental study was made to obtain heat transfer and air temperature data for a simple 3-leg serpentine test section that simulates a turbine blade internal cooling passage with trip strips and bleed holes. The objectives were to investigate the interaction of ribs and various bleed conditions on internal cooling and to gain a better understanding of bulk air temperature in an internal passage. Steady state heat transfer measurements were obtained using a transient technique with thermochromic liquid crystals. Trip strips were attached to one wall of the test section and were located either between or near the bleed holes. The bleed holes, used for film cooling, were metered to simulate the effect of external pressure on the turbine blade. Heat transfer enhancement was found to be greater for ribs near bleed holes compared to ribs between holes, and both configurations were affected slightly by bleed rates upstream. Air temperature measurements were taken at discreet locations along one leg of the model. Average bulk air temperatures were found to remain fairly constant along one leg of the model.

  10. Comparison of Organ Location, Morphology, and Rib Coverage of a Midsized Male in the Supine and Seated Positions

    PubMed Central

    Hayes, Ashley R.; Gayzik, F. Scott; Moreno, Daniel P.; Martin, R. Shayn; Stitzel, Joel D.

    2013-01-01

    The location and morphology of abdominal organs due to postural changes have implications in the prediction of trauma via computational models. The purpose of this study is to use data from a multimodality image set to devise a method for examining changes in organ location, morphology, and rib coverage from the supine to seated postures. Medical images of a male volunteer (78.6 ± 0.77 kg, 175 cm) in three modalities (Computed Tomography, Magnetic Resonance Imaging (MRI), and Upright MRI) were used. Through image segmentation and registration, an analysis between organs in each posture was conducted. For the organs analyzed (liver, spleen, and kidneys), location was found to vary between postures. Increases in rib coverage from the supine to seated posture were observed for the liver, with a 9.6% increase in a lateral projection and a 4.6% increase in a frontal projection. Rib coverage area was found to increase 11.7% for the spleen. Morphological changes in the organs were also observed. The liver expanded 7.8% cranially and compressed 3.4% and 5.2% in the anterior-posterior and medial-lateral directions, respectively. Similar trends were observed in the spleen and kidneys. These findings indicate that the posture of the subject has implications in computational human body model development. PMID:23606901

  11. Prediction of physical and chemical body compositions of purebred and crossbred Nellore cattle using the composition of a rib section.

    PubMed

    Marcondes, M I; Tedeschi, L O; Valadares Filho, S C; Chizzotti, M L

    2012-04-01

    The goal of this research was to develop empirical equations to predict chemical and physical compositions of the carcass and the body using the composition of the 9th- to 11th-rib section (rib(9-11)) and other measurements. A database (n = 246) from 6 studies was developed and comprised 37 bulls (BU), 115 steers (STR), and 94 heifers (HF), of which 132 were Nellore (NEL), 76 were NEL × Angus crossbreds (NA), and 38 were NEL × Simmental crossbreds (NS). The right half carcass and the rib(9-11) from the left half carcass were analyzed for ether extract (EE), CP, and water. The remaining components were chemically analyzed to determine the composition of the body. A stepwise procedure was used to determine the variable inclusion in the regression models. The variables included were EE in the rib(9-11) (EER; %), CP in the rib(9-11) (CPR; %), water in the rib(9-11) (WR; %), visceral fat (VF; %; KPH and mesenteric fats), organs plus viscera (OV; %), carcass dressing percentage (CD; %), cold carcass weight (kg), and empty BW (EBW; kg). No sex or breed effects were found on EE and CP compositions of the carcass (C(EE) and C(CP), respectively; %); the equations were as follows: C(EE) = 4.31 + 0.31 × EER + 1.37 × VF [n = 241; R(2) = 0.83; mean square error (MSE) = 4.53] and C(CP) = 17.92 + 0.60 × CPR - 0.17 × CD (n = 238; R(2) = 0.50; MSE = 1.58). Breed affected water content in the carcass (C(W), %); the equations were as follows: C(W) = 48.74 + 0.28 × WR - 0.017 × EBW for NEL; C(W) = 46.69 + 0.32 × WR - 0.017 × EBW for NA; and C(W) = 38.06 + 0.48 × WR - 0.017 × EBW for NS (n = 243; R(2) = 0.67; MSE = 5.17). A sex effect was found on body chemical EE composition (BW(EE)); the equations were as follows: BW(EE) = 2.75 + 0.33 × EER + 1.80 × VF for BU; BW(EE) = 1.84 + 0.33 × EER + 1.91 × VF for STR; and BW(EE) = 4.77 + 0.33 × EER + 1.28 × VF for HF (n = 243; R(2) = 0.89; MSE = 3.88). No sex or breed effects were found on CP composition in the body (BW

  12. A High Efficiency, Kinetic-Ejection Negative Ion Source for RIB Generation

    SciTech Connect

    Alton, G.D.; Liu, Y.; Murray, S.N.; Williams, C.

    1998-10-05

    Chemically active radioactive species, diffused from RIB target materials, often arrive at the ionization chamber of the source in a variety of molecular forms. Because of the low probability for simultaneously dissociating and efficiently ionizing the individual atomic constituents of molecules with conventional hot-cathode electron-impact ion sources, the species of interest are often distributed in several mass channels in the form of molecular side-band beams and consequently, their intensities are diluted. The sputter negative ion beam generation technique offers an efficient means for simultaneously dissociating and ionizing highly electronegative atomic species present in molecular carriers. We have incorporated these principles in the design and fabrication of a kinetic ejection negative ion source and evaluated its potential for generating {sup 17,18}F{sup {minus}} beams for the Holifield Radioactive Ion Beam Facility astrophysics research program. The source utilizes Cs{sup +} beams to bombard condensable fluorine compounds that emanate from a target material, such as Al{sub 2}O{sub 3}, and are transported to the cooled inner surface of a conical-geometry cathode where they are adsorbed. The energetic Cs{sup +} beams efficiently dissociate these molecules and sputter their constituents. Since the work functions of cesiated surfaces are low, highly electronegative species such as fluorine are efficiently ionized in the sputter-injection process. Measured efficiencies for ionizing atomic fluorine, dissociated from condensable compounds that are formed by reactions of SF{sub 6} with fibrous Al{sub 2}O{sub 3} material, exceed 6.5%. In this report, we describe the mechanical design features and principles of operation, and present emittance, F{sup {minus}} yield and ionization efficiency data derived from off-line, experimental evaluation of the source.

  13. The role of acoustic nonlinearity in tissue heating behind a rib cage using a high-intensity focused ultrasound phased array

    NASA Astrophysics Data System (ADS)

    Yuldashev, Petr V.; Shmeleva, Svetlana M.; Ilyin, Sergey A.; Sapozhnikov, Oleg A.; Gavrilov, Leonid R.; Khokhlova, Vera A.

    2013-04-01

    The goal of this study was to investigate theoretically the effects of nonlinear propagation in a high-intensity focused ultrasound (HIFU) field produced by a therapeutic phased array and the resultant heating of tissue behind a rib cage. Three configurations of focusing were simulated: in water, in water with ribs in the beam path and in water with ribs backed by a layer of soft tissue. The Westervelt equation was used to model the nonlinear HIFU field, and a 1 MHz phased array consisting of 254 circular elements was used as a boundary condition to the model. The temperature rise in tissue was modelled using the bioheat equation, and thermally necrosed volumes were calculated using the thermal dose formulation. The shapes of lesions predicted by the modelling were compared with those previously obtained in in vitro experiments at low-power sonications. Intensity levels at the face of the array elements that corresponded to the formation of high-amplitude shock fronts in the focal region were determined as 10 W cm-2 in the free field in water and 40 W cm-2 in the presence of ribs. It was shown that exposures with shocks provided a substantial increase in tissue heating, and its better spatial localization in the main focal region only. The relative effects of overheating ribs and splitting of the focus due to the periodic structure of the ribs were therefore reduced. These results suggest that utilizing nonlinear propagation and shock formation effects can be beneficial for inducing confined HIFU lesions when irradiating through obstructions such as ribs. Design of compact therapeutic arrays to provide maximum power outputs with lower intensity levels at the elements is necessary to achieve shock wave regimes for clinically relevant sonication depths in tissue.

  14. Shaping frequency response of a vibrating plate for passive and active control applications by simultaneous optimization of arrangement of additional masses and ribs. Part II: Optimization

    NASA Astrophysics Data System (ADS)

    Wrona, Stanislaw; Pawelczyk, Marek

    2016-03-01

    It was shown in Part I that an ability to shape frequency response of a vibrating plate according to precisely defined demands has a very high practical potential. It can be used to improve acoustic radiation of the plate for required frequencies or enhance acoustic isolation of noise barriers and device casings. It can be used for both passive and active control. The proposed method is based on mounting several additional ribs and masses (passive and/or active) to the plate surface at locations followed from an optimisation process. In Part I a relevant model of such structure, as a function of arrangement of the additional elements was derived and validated. The model allows calculating natural frequencies and mode-shapes of the whole structure. The aim of this companion paper, Part II, is to present the second stage of the method. This is an optimization process that results in arrangement of the elements guaranteeing desired plate frequency response, and enhancement of controllability and observability measures. For that purpose appropriate cost functions, and constraints followed from technological feasibility are defined. Then, a memetic algorithm is employed to obtain a numerical solution with parameters of the arrangement. The optimization results are initially presented for simple cases to validate the method. Then, more complex scenarios are analysed with very special demands concerning the frequency response to present the full potential of the method. Subsequently, a laboratory experiment is presented and discussed. Finally, other areas of applications of the proposed method are shown and conclusions for future research are drawn.

  15. Investigation of heat transfer and flow using ribs within gas turbine blade cooling passage: Experimental and hybrid LES/RANS modeling

    NASA Astrophysics Data System (ADS)

    Kumar, Sourabh

    Gas turbines are extensively used for aircraft propulsion, land based power generation and various industrial applications. Developments in innovative gas turbine cooling technology enhance the efficiency and power output, with an increase in turbine rotor inlet temperatures. These advancements of turbine cooling have allowed engine design to exceed normal material temperature limits. For internal cooling design, techniques for heat extraction from the surfaces exposed to hot stream are based on the increase of heat transfer areas and on promotion of turbulence of the cooling flow. In this study, it is obtained by casting repeated continuous V and broken V shaped ribs on one side of the two pass square channel into the core of blade. Despite extensive research on ribs, only few papers have validated the numerical data with experimental results in two pass channel. In the present study, detailed experimental investigation is carried out for two pass square channels with 180° turn. Detailed heat transfer distribution occurring in the ribbed passage is reported for steady state experiment. Four different combinations of 60° and Broken 60° V ribs in channel are considered. Thermocouples are used to obtain the temperature on the channel surface and local heat transfer coefficients are obtained for various Reynolds numbers, within the turbulent flow regime. Area averaged data are calculated in order to compare the overall performance of the tested ribbed surface and to evaluate the degree of heat transfer enhancement induced by the ribs with. Flow within the channels is characterized by heat transfer enhancing ribs, bends, rotation and buoyancy effects. Computational Fluid Dynamics (CFD) simulations were carried out for the same geometries using different turbulence models such as k-o Shear stress transport (SST) and Reynolds stress model (RSM). These CFD simulations were based on advanced computing in order to improve the accuracy of three dimensional metal

  16. Rib stress fracture in a male adaptive rower from the arms and shoulders sport class: case report

    PubMed Central

    Smoljanović, Tomislav; Bojanić, Ivan; Pollock, Courtney L.; Radonić, Radovan

    2011-01-01

    Adaptive rowing is rowing or sculling for rowers with a physical disability. It debuted at the Paralympic Games in 2008. In order to ensure an equitable playing field, rowers with similar levels of physical function and disability are classified into different sport classes for competition. Rowers with an inability to use a sliding seat and impaired trunk function resulting in an inability to perform trunk forward and backward lean via hip flexion/extension are assigned to the Arms and Shoulders (AS) class. AS rowers have to use a chest strap set immediately below the chest in order to localize any trunk movement in AS class. Conditions created by adaptations of rowing equipment and technique within the AS class create unique stresses on the upper thoracic region. The following case report demonstrates how etiology and management of a rib stress fracture in an AS rower differs in comparison to able-body rowers. Of significant importance were the limitations imposed on the rower’s ability to maintain rowing-specific fitness, due to the nature of the rib stress fracture and requirement to decrease force transmission through the ribs for several weeks. The rower’s gradual return to full training was further impacted by obligatory use of the chest strap, which directly applied pressure over the injured area. Protective orthosis for the chest was designed and applied in order to dissipate pressure of the chest strap over the thorax during rowing (most importantly at the catch position) both on the ergometer and in the boat. PMID:21990083

  17. The effect of the periosteum and strain gages on the structural response of human ribs - biomed 2009.

    PubMed

    Kemper, Andrew R; McNally, Craig; Duma, Steffany M

    2009-01-01

    The purpose of this study was to determine if the removal of the periosteum or the application of a strain gage has any significant effect on the structural response of human ribs. A total of 32 three-point bending tests were performed on 16 matched whole rib sections obtained from the left and right sides of five male human thoraces. For one test group, matched specimens were tested to determine the effect of removing the soft tissue and periosteum versus leaving it intact. For a second test group, matched specimens were tested to determine the effects of placing a strain gage on the tension side of the specimen versus no strain gage attachment. The specimens were tested using a servo-hydraulic material testing machine (MTS) at a displacement rate of 17.78 cm/s with a fixed testing span of 10.16 cm. Prior to testing, a microCT was used to obtain a detailed cross-sectional image of each specimen at the point of the impactor blade contact. There were no statistical differences in area moment of inertia (p=0.60), distance to the neutral axis (p=0.29), peak moment (p=0.14), peak impactor displacement (p=0.13), estimated peak stress (p=0.42), or estimated peak strain (p=0.15) between specimens with the periosteum and those without the periosteum. There were no statistical differences in area moment of inertia (p=0.76), distance to the neutral axis (p=0.20), peak moment (p=0.81), peak impactor displacement (p=0.91), estimated peak stress (p=0.59), or estimated peak strain (p=0.29) between specimens with a strain gage and those without a strain gage. In summary, neither the removal of the periosteum nor the application of a strain gage has any significant effect on the structural response of human ribs in dynamic three-point bending. PMID:19369732

  18. On pains of the kidney and the bladder in Kitāb al-Tajārib by Rhazes.

    PubMed

    Aciduman, Ahmet

    2016-02-01

    Abū Bakr Muḥammad ibn Zakariyyā al-Rāzī (865-925), known in the West as Rhazes, was one of the pioneer figures of the golden age of Islamic science and medicine during the middle ages. Kiṭab al-Ḥāwī fī al-Ṭibb (Liber Continens), Kitāb al-Ṭibb al-Manṣūrī (Liber Medicinalis ad Almansorem) and Kitāb al-Judarī wa al-Ḥaṣba (Liber de Pestilentia) are his very well-known works in medicine. One of his books Kitāb al-Tajārib (The Book of Experiences/The Casebook), was written in Arabic and one of its copies is Ahmed III, Nr. 1975 manuscript in Topkapı Palace Library in Istanbul. A physician, Ali Munshi of Bursa, translated Kitāb al-Tajārib into Turkish in the 18th century and Hamidiye, Nr. 1013; Veliyuddin Efendi, Nr. 2487 and orum, Nr. 2909 manuscripts are the copies of its Turkish translation in different libraries in Turkey. Both the book and its Turkish translation contain 31 chapters; 30 of them concerning diseases from head to heel and the last one on pharmaceutics. The 21st chapter, fī awjā' al-kulā wa al-mathāna wa al-bāh, of Kitāb al-Tajārib is on pains of the kidney, and the bladder, and coitus. Evaluation and presentation of the cases in this chapter regarding the kidney and the bladder are the aims of this report. PMID:26913876

  19. Ribbed moraines in northern Manitoba, Canada: characteristics and preservation as part of a subglacial bed mosaic near the core regions of ice sheets

    NASA Astrophysics Data System (ADS)

    Trommelen, Michelle S.; Ross, Martin; Ismail, Ahmed

    2014-03-01

    Ribbed moraines are enigmatic glacial landforms for which different models, with contrasting paleoglaciologic implications, have been proposed to explain their formation. Despite the great deal of attention this type of landform has received over the last several decades, ribbed moraine fields in northern Manitoba, Canada are among the largest in the world but have been seldom studied. Ribbed moraines in this part of the world overlie the low-relief Canadian Shield, are not constrained by topography, and are part of a spatial subglacial-landform assemblage associated with drumlinoid ridges within palimpsest and relict-type Glacial Terrain Zones. Field observations herein provide new insights into the characteristics of these transverse-to ice-flow ridges at landscape (mapping and spatial analysis) and landform (internal structure using high-resolution shear wave (S-wave) seismic reflection surveys, sedimentological characteristics, clast-fabric analyses) scales. Two main types of ribbed moraine are recognized: 'pristine', high amplitude straight-crested ridges and secondarily-modified subdued 'drumlinized' ridges. Ribbed moraine in northeast Manitoba consist of massive, matrix-supported till at surface, which is similar in matrix texture and composition to the regional till sheet, though pristine moraines show a higher concentration of boulders. A seismic profile reveals subparallel-to surface layered stratigraphy with only minor folding and no major unconformities (stacking or faulting).

  20. Dynamic simulations of under-rib convection-driven flow-field configurations and comparison with experiment in polymer electrolyte membrane fuel cells

    NASA Astrophysics Data System (ADS)

    Duy, Vinh Nguyen; Lee, Jungkoo; Kim, Kyungcheol; Ahn, Jiwoong; Park, Seongho; Kim, Taeeun; Kim, Hyung-Man

    2015-10-01

    The under-rib convection-driven flow-field design for the uniform distribution of reacting gas and the generation of produced water generates broad scientific interest, especially among those who study the performance of polymer electrolyte membrane fuel cells (PEMFCs). In this study, we simulate the effects of an under-rib convection-driven serpentine flow-field with sub-channel and by-pass (SFFSB) and a conventional advanced serpentine flow-field (CASFF) on single cell performance, and we compare the simulation results with experimental measurements. In the under-rib convection-driven flow-field configuration with SFFSB, the pressure drop is decreased because of the greater cross-sectional area for gas flow, and the decreased pressure drop results in the reduction of the parasitic loss. The anode liquid water mass fraction increases with increasing channel height because of increased back diffusion, while the cathode liquid water mass fraction does not depend upon the sub-channels but is ascribed mainly to the electro-osmotic drag. Simulation results verify that the maximum current and the power densities of the SFFSB are increased by 18.85% and 23.74%, respectively, due to the promotion of under-rib convection. The findings in this work may enable the optimization of the design of under-rib convection-driven flow-fields for efficient PEMFCs.

  1. Bone mineral density, rib pain and other features of the female athlete triad in elite lightweight rowers

    PubMed Central

    Dimitriou, Lygeri; Weiler, Richard; Lloyd-Smith, Rebecca; Turner, Antony; Heath, Luke; James, Nic; Reid, Anna

    2014-01-01

    Objective To determine bone mineral density (BMD) and the associations among BMD, menstrual history, disordered eating (DE), training history, intentional weight loss (IWL) and rib pain for the first time in female lightweight rowers. Setting 9 lightweight rowing clubs, UK. Participants 29 Caucasian female lightweight rowers volunteered. 21 (12 active, 9 retired) completed the study. Inclusion criteria: female lightweight rowers aged over 18 years. Exclusion criteria: participants with a history of bone disease, used medications known to influence BMD or if they were pregnant, lactating or postmenopausal. Main outcome measures Dual-energy X-ray absorptiometry measured total body (TB) composition and BMD at the spine, femoral neck (FN), radius and TB. DE, oligomenorrhoea/amenorrhoea years; rib pain and training history. Results DE was reported in six of the rowers. The active with DE started rowing younger (p<0.05) than those without, and their amount of IWL was associated with Eating Attitudes Test-26 score (p<0.05). Some participants reported a history of oligomenorrhoea/amenorrhoea 17 (76%) and/or rib pain 7 (32%) with those with rib pain having lower spine and TB Z-scores (p<0.05) than those without. Those with oligomenorrhoea/amenorrhoea had lower spine Z-scores (p<0.01) than those without. Twelve participants had low BMD; three at spine; one at FN; and eight at radius. Thirteen per cent of mean total training hours (18.6±9.1 h/week) were spent strength training (2.4±2.2 h/week). Conclusions Upper body exercises incorporating multidimensional high peak bone strain were not reported and may need to be considered in their strength training to improve radial BMD. Results suggest IWL and high-level training at a young age increases the likelihood of DE and there may be a lack of quality nutritional support for these athletes. Thus, multidisciplinary sport science support should be offered at a young age and perhaps also to consider changing the weight rules

  2. Experimental demonstration of linearly polarized 2-10  μm supercontinuum generation in a chalcogenide rib waveguide.

    PubMed

    Yu, Yi; Gai, Xin; Ma, Pan; Vu, Khu; Yang, Zhiyong; Wang, Rongping; Choi, Duk-Yong; Madden, Steve; Luther-Davies, Barry

    2016-03-01

    This Letter reports the production of a supercontinuum extending from ≈2  μm to >10  μm generated using a chalcogenide buried rib waveguide pumped with 330 femtosecond pulses at 4.184 μm. This is, to the best of our knowledge, the broadest mid-infrared supercontinuum generated in any planar waveguide platform. Because the waveguide is birefringent, quasi-single-mode, and uses an optimized dispersion design, the supercontinuum is linearly polarized with an extinction ratio >100. Dual beam spectrophotometry is performed easily using this source. PMID:26974090

  3. Vibration isolation

    NASA Technical Reports Server (NTRS)

    Bastin, Paul

    1990-01-01

    Viewgraphs on vibration isolation are presented. Techniques to control and isolate centrifuge disturbances were identified. Topics covered include: disturbance sources in the microgravity environment; microgravity assessment criteria; life sciences centrifuge; flight support equipment for launch; active vibration isolation system; active balancing system; and fuzzy logic control.

  4. Dual-Tapered 10-µm-Spot-Size Converter with Double Core for Coupling Polarization-Independent Silicon Rib Waveguides to Single-Mode Optical Fibers

    NASA Astrophysics Data System (ADS)

    Tokushima, Masatoshi; Kamei, Akio; Horikawa, Tsuyoshi

    2012-02-01

    A new spot-size converter (SSC) for coupling Si rib waveguides to 10-µm-mode-diameter single mode optical fibers was theoretically and experimentally evaluated. The core of the SSC consisted of a lateral and vertical Si inverse-taper having a rib-to-wire shape and a lateral silica normal-taper with a rib shape. The calculated coupling losses for an optimized structure were 0.65 and 0.66 dB for transverse-electric (TE) and transverse-magnetic (TM) polarizations, respectively. The losses of the fabricated SSCs were 2.7 dB (TE) and 3.0 dB (TM). The measured misalignment tolerance was +/-1.2 µm for an extra-loss increase of 0.25 dB.

  5. Ketamine Infusion Therapy as an Alternative Pain Control Strategy in Patients with Multi-Trauma including Rib Fracture; Case Report and Literature Review

    PubMed Central

    Losing, Ashley K; Jones, Justin M; Keric, Adis; Briggs, Steven E; Leedahl, David D

    2016-01-01

    Ketamine is a promising alternative agent for pain control that offers benefit to traditional strategies, particularly in the setting of rib fracture. Current pharmacologic therapies have clear adverse effects, and other options may be invasive, cost prohibitive, or marginally effective. We describe three consecutive patients with traumatic injuries including rib fracture for which a ketamine infusion was utilized as part of their pain control strategy.  For each patient, use of a ketamine infusion trended toward reduced opioid requirements with stable pain scores. One patient experienced a dissociative adverse effect prompting decrease and discontinuation of ketamine. No pulmonary complications in the form of emergent intubation or new diagnosis of pneumonia were observed. We believe the addition of ketamine infusion to be a valid alternative strategy for managing pain associated with rib fracture. PMID:27540552

  6. Ketamine Infusion Therapy as an Alternative Pain Control Strategy in Patients with Multi-Trauma including Rib Fracture; Case Report and Literature Review.

    PubMed

    Losing, Ashley K; Jones, Justin M; Keric, Adis; Briggs, Steven E; Leedahl, David D

    2016-07-01

    Ketamine is a promising alternative agent for pain control that offers benefit to traditional strategies, particularly in the setting of rib fracture. Current pharmacologic therapies have clear adverse effects, and other options may be invasive, cost prohibitive, or marginally effective. We describe three consecutive patients with traumatic injuries including rib fracture for which a ketamine infusion was utilized as part of their pain control strategy.  For each patient, use of a ketamine infusion trended toward reduced opioid requirements with stable pain scores. One patient experienced a dissociative adverse effect prompting decrease and discontinuation of ketamine. No pulmonary complications in the form of emergent intubation or new diagnosis of pneumonia were observed. We believe the addition of ketamine infusion to be a valid alternative strategy for managing pain associated with rib fracture. PMID:27540552

  7. Long-term nipple shrinkage following augmentation by an autologous rib cartilage transplant in free DIEP-flaps.

    PubMed

    Heitland, A; Markowicz, M; Koellensperger, E; Allen, R; Pallua, N

    2006-01-01

    Aesthetically pleasing nipple-areola reconstruction is a satisfying part of a two-stage breast reconstruction. The up to 50% [Banducci DR, Le TK, Hughes KC. Long-term follow-up of a modified Anton-Hartrampf nipple reconstruction. Ann Plast Surg 1999;43(5):467-9; discussion 469-70] postoperative shrinkage following a conventional nipple reconstruction is a well-known problem. Augmentation of the nipple with autologous banked cartilage seems to be a promising solution. From 2000-2003, 17 patients underwent a nipple-areola-complex reconstruction following secondary breast reconstruction using free perforator flaps. The rib cartilage harvested during the preparation of the internal thoracic vessels was banked subcutaneously and six months later replanted under the 'arrow flap' after contouring it in a 'mushroom' shape. One year later the shrinkage of the nipple in comparison to the intraoperative status was measured. In addition, patients were asked about their personal palpation impression and the aesthetic outcome. The average height decreased one year postoperatively about 25%. Thirteen of 17 patients judged the aesthetic outcome as very good, 16 nipples healed without cartilage protrusion and no patient felt discomfortable stiffness of the nipple. Our concept of a nipple augmentation with rib cartilage improves the projection and allows a more correct judgement of the later nipple shrinkage. We consider this technique to be an aesthetically satisfying and safe method, which could be used with any kind of breast reconstruction. PMID:16996429

  8. Surgical Management of Intracanal Rib Head Dislocation in Neurofibromatosis Type 1 Dystrophic Kyphoscoliosis: Report of Two Cases and Literature Review

    PubMed Central

    Bounakis, Nikolaos; Garrido-Stratenwerth, Enrique

    2016-01-01

    There is still no consensus on the management of severe intracanal RH dislocation in neurofibromatosis type 1 dystrophic kyphoscoliosis. This study notes the early cord function impairment signs, reports a serious complication in a susceptible cord, identifies possible mechanisms of injury, and discusses the management of intracanal RH dislocation presented in the literature. First report is as follows: a 12-year-old female with cord compromise and preoperative neurology that underwent thoracotomy and anterior release. The RH was left in situ following a rib excision. During the posterior stage of the procedure she presented with complete loss of all IOM traces prior to any correction manoeuvres. The neurology recovered 72 h postop and the final correction and instrumented fusion were uneventfully completed 15 days postop. Second report is as follows: a 10-year-old male, whose only neurology was a provoked shock-like sensation to the lower limbs following direct pressure on the rib cage. He underwent an uneventful posterior RH excision and instrumented correction and posterior spinal fusion. In conclusion, any possible cord dysfunction sign should be sought during examination. Decompression of the spinal cord by resecting the impinging bony part, even in the absence of neurological symptoms, is advised before any attempt to release or correct the deformity. PMID:27446620

  9. Measurements of heat transfer coefficients and friction factors in rib-roughened channels simulating leading-edge cavities of a modern turbine blade

    SciTech Connect

    Taslim, M.E.; Li, T.; Spring, S.D.

    1997-07-01

    Leading edge cooling cavities in modern gas turbine blades play an important role in maintaining the leading edge temperature at levels consistent with air foil design life. These cavities often have a complex cross-sectional shape to be compatible with the external contour of the blade at the leading edge. A survey of many existing geometries shows that, for analytical as well as experimental analyses, such cavities can be simplified in shape by a four-sided polygon with one curved side similar to the leading edge curvature, a rectangle with one semicircular side (often the smaller side) or a trapezoid, the smaller base of which is replaced by a semicircle. Furthermore, to enhance the heat transfer coefficient in these cavities, they are mostly roughened on three sides with ribs of different geometries. Experimental data on friction factors and heat transfer coefficients in such cavities are rare if not nonexistent. A liquid crystal technique was used in this experimental investigation to measure heat transfer coefficients in six test sections representing the leading-edge cooling cavities. Both straight and tapered ribs were configured on the two opposite sidewalls in a staggered arrangement with angles of attack to the mainstream flow, {alpha}, of 60 and 90 deg. The ribs on the curved surface were of constant cross section with an angle of attack 90 deg to the flow. Heat transfer measurements were performed on the straight sidewalls, as well as on the round surface adjacent to the blade leading edge. Effects such as rib angle of attack to the mainstream flow and constant versus tapered rib cross-sectional areas were also investigated. Nusselt numbers, friction factors, and thermal performances are reported for nine rib geometries in six test sections.

  10. Clavicles, interclavicles, gastralia, and sternal ribs in sauropod dinosaurs: new reports from diplodocidae and their morphological, functional and evolutionary implications.

    PubMed

    Tschopp, Emanuel; Mateus, Octávio

    2013-03-01

    Ossified gastralia, clavicles and sternal ribs are known in a variety of reptilians, including dinosaurs. In sauropods, however, the identity of these bones is controversial. The peculiar shapes of these bones complicate their identification, which led to various differing interpretations in the past. Here we describe different elements from the chest region of diplodocids, found near Shell, Wyoming, USA. Five morphotypes are easily distinguishable: (A) elongated, relatively stout, curved elements with a spatulate and a bifurcate end resemble much the previously reported sauropod clavicles, but might actually represent interclavicles; (B) short, L-shaped elements, mostly preserved as a symmetrical pair, probably are the real clavicles, as indicated by new findings in diplodocids; (C) slender, rod-like bones with rugose ends are highly similar to elements identified as sauropod sternal ribs; (D) curved bones with wide, probably medial ends constitute the fourth morphotype, herein interpreted as gastralia; and (E) irregularly shaped elements, often with extended rugosities, are included into the fifth morphotype, tentatively identified as sternal ribs and/or intercostal elements. To our knowledge, the bones previously interpreted as sauropod clavicles were always found as single bones, which sheds doubt on the validity of their identification. Various lines of evidence presented herein suggest they might actually be interclavicles - which are single elements. This would be the first definitive evidence of interclavicles in dinosauromorphs. Previously supposed interclavicles in the early sauropodomorph Massospondylus or the theropods Oviraptor and Velociraptor were later reinterpreted as clavicles or furculae. Independent from their identification, the existence of the reported bones has both phylogenetic and functional significance. Their presence in non-neosauropod Eusauropoda and Flagellicaudata and probable absence in rebbachisaurs and Titanosauriformes shows a

  11. Clavicles, interclavicles, gastralia, and sternal ribs in sauropod dinosaurs: new reports from Diplodocidae and their morphological, functional and evolutionary implications

    PubMed Central

    Tschopp, Emanuel; Mateus, Octávio

    2013-01-01

    Ossified gastralia, clavicles and sternal ribs are known in a variety of reptilians, including dinosaurs. In sauropods, however, the identity of these bones is controversial. The peculiar shapes of these bones complicate their identification, which led to various differing interpretations in the past. Here we describe different elements from the chest region of diplodocids, found near Shell, Wyoming, USA. Five morphotypes are easily distinguishable: (A) elongated, relatively stout, curved elements with a spatulate and a bifurcate end resemble much the previously reported sauropod clavicles, but might actually represent interclavicles; (B) short, L-shaped elements, mostly preserved as a symmetrical pair, probably are the real clavicles, as indicated by new findings in diplodocids; (C) slender, rod-like bones with rugose ends are highly similar to elements identified as sauropod sternal ribs; (D) curved bones with wide, probably medial ends constitute the fourth morphotype, herein interpreted as gastralia; and (E) irregularly shaped elements, often with extended rugosities, are included into the fifth morphotype, tentatively identified as sternal ribs and/or intercostal elements. To our knowledge, the bones previously interpreted as sauropod clavicles were always found as single bones, which sheds doubt on the validity of their identification. Various lines of evidence presented herein suggest they might actually be interclavicles – which are single elements. This would be the first definitive evidence of interclavicles in dinosauromorphs. Previously supposed interclavicles in the early sauropodomorph Massospondylus or the theropods Oviraptor and Velociraptor were later reinterpreted as clavicles or furculae. Independent from their identification, the existence of the reported bones has both phylogenetic and functional significance. Their presence in non-neosauropod Eusauropoda and Flagellicaudata and probable absence in rebbachisaurs and Titanosauriformes shows a

  12. Nutrient database improvement project: Separable components and proximate composition of raw and cooked retail cuts from the beef rib and plate

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Beef nutrition is very important to the worldwide beef industry and its consumers. The objective of this study was to analyze nutrient composition of eight beef rib and plate cuts to update the nutrient data in the USDA National Nutrient Database for Standard Reference (SR). Seventy-two carcasses ...

  13. Effects of winter stocker growth rate and finishing system on: II. 9-10-11th rib composition, muscle color, and palatability

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Angus-cross steers (n = 198) were used in a three-year study to assess the effects of winter stocker growth rate and finishing system on rib composition, color and palatability. During the winter months, steers were randomly allotted to three stocker growth rates: low (0.23 kg/d; LOW), medium (0.45...

  14. COMPARISON OF PCB AND TRACE METAL BIOACCUMULATION IN THE BLUE MUSSEL, MYTILUS EDULIS, AND THE RIBBED MUSSEL, MODIOLUS DEMISSUS, IN NEW BEDFORD HARBOR, MASSACHUSETTS

    EPA Science Inventory

    The accumulation of PCBs and trace metals was compared at 14-d intervals between two filter-feeding bivalves, the blue mussel, Mytilus edulis, and the ribbed mussel, Modiolus demissus, after deployment in New Bedford Harbor, Massachusetts, for up to 56 d. Contaminant uptake in de...

  15. Utility of a 3-dimensional full-scale NaCl model for rib strut grafting for anterior fusion for cervicothoracic kyphosis

    PubMed Central

    Kobayashi, Kazuyoshi; Imagama, Shiro; Muramoto, Akio; Ito, Zenya; Ando, Kei; Yagi, Hideki; Hida, Tetsuro; Ito, Kenyu; Ishikawa, Yoshimoto; Tsushima, Mikito; Ishiguro, Naoki

    2015-01-01

    ABSTRACT In severe spinal deformity, pain and neurological disorder may be caused by spinal cord compression. Surgery for spinal reconstruction is desirable, but may be difficult in a case with severe deformity. Here, we show the utility of a 3D NaCl (salt) model in preoperative planning of anterior reconstruction using a rib strut in a 49-year-old male patient with cervicothoracic degenerative spondylosis. We performed surgery in two stages: a posterior approach with decompression and posterior instrumentation with a pedicle screw; followed by a second operation using an anterior approach, for which we created a 3D NaCl model including the cervicothoracic lesion, spinal deformity, and ribs for anterior reconstruction. The 3D NaCl model was easily scraped compared with a conventional plaster model and was useful for planning of resection and identification of a suitable rib for grafting in a preoperative simulation. Surgery was performed successfully with reference to the 3D NaCl model. We conclude that preoperative simulation with a 3D NaCl model contributes to performance of anterior reconstruction using a rib strut in a case of cervicothoracic deformity. PMID:26412901

  16. Validated heat-transfer and pressure-drop prediction methods based on the discrete-element method: Phase 2, two-dimensional rib roughness

    SciTech Connect

    James, C.A.; Hodge, B.K.; Taylor, R.P.

    1993-05-01

    Surface roughness is a commonly used approach for enhancing the rate of heat transfer of surfaces, such as in heat-exchanger tubes. Because the improved thermal performance of roughened surfaces is at the expense of increased flow resistance (increased pressure drop or friction factor), accurate prediction techniques for determining the friction factors and Nusselt numbers for roughened surfaces are required if such features are to be considered as design options. This report presents the results of the second phase of a research program sponsored by Argonne National Laboratory to validate models for the prediction of friction factors and Nusselt numbers for fully developed turbulent flow in enhanced heat-exchanger tubes. The first phase was concerned with validating a roughness model for turbulent flow in tubes internally roughened with three-dimensional distributed roughness elements, such as sandgrains, spheres, hemispheres, and cones. The second phase is concerned with devising and validating methods for the prediction of friction factors and Nusselt numbers for turbulent flow in tubes internally roughened with repeated, two-dimensional ribs aligned perpendicular to the flow. The ribs are spaced sufficiently far apart that the leeward-side separated flow reattaches to the wall before again separating in order to negotiate the next rib. This heat-transfer enhancement mechanism is called the separation and reattachment mechanism, after Rabas (1989). This work is limited to rectangular rib shapes.

  17. Mutations in KIAA0586 Cause Lethal Ciliopathies Ranging from a Hydrolethalus Phenotype to Short-Rib Polydactyly Syndrome.

    PubMed

    Alby, Caroline; Piquand, Kevin; Huber, Céline; Megarbané, André; Ichkou, Amale; Legendre, Marine; Pelluard, Fanny; Encha-Ravazi, Ferechté; Abi-Tayeh, Georges; Bessières, Bettina; El Chehadeh-Djebbar, Salima; Laurent, Nicole; Faivre, Laurence; Sztriha, László; Zombor, Melinda; Szabó, Hajnalka; Failler, Marion; Garfa-Traore, Meriem; Bole, Christine; Nitschké, Patrick; Nizon, Mathilde; Elkhartoufi, Nadia; Clerget-Darpoux, Françoise; Munnich, Arnold; Lyonnet, Stanislas; Vekemans, Michel; Saunier, Sophie; Cormier-Daire, Valérie; Attié-Bitach, Tania; Thomas, Sophie

    2015-08-01

    KIAA0586, the human ortholog of chicken TALPID3, is a centrosomal protein that is essential for primary ciliogenesis. Its disruption in animal models causes defects attributed to abnormal hedgehog signaling; these defects include polydactyly and abnormal dorsoventral patterning of the neural tube. Here, we report homozygous mutations of KIAA0586 in four families affected by lethal ciliopathies ranging from a hydrolethalus phenotype to short-rib polydactyly. We show defective ciliogenesis, as well as abnormal response to SHH-signaling activation in cells derived from affected individuals, consistent with a role of KIAA0586 in primary cilia biogenesis. Whereas centriolar maturation seemed unaffected in mutant cells, we observed an abnormal extended pattern of CEP290, a centriolar satellite protein previously associated with ciliopathies. Our data show the crucial role of KIAA0586 in human primary ciliogenesis and subsequent abnormal hedgehog signaling through abnormal GLI3 processing. Our results thus establish that KIAA0586 mutations cause lethal ciliopathies. PMID:26166481

  18. Diffuse lymphatic leakage after continuous vacuum-assisted closure therapy for thoracic wound infection after rib stabilization.

    PubMed

    Dackam, Sandrine; Furrer, Katarzyna; Haug, Martin; Lardinois, D

    2015-01-01

    Vacuum-assisted closure (VAC) therapy is a useful tool in the management of a wide spectrum of complex wounds in cardiothoracic surgery. It promotes healing through the application of a controlled and localized negative pressure on porous polyurethane absorbent foams. Known advantages of the VAC therapy are the acceleration of wound healing, stimulation of granulation tissue and reduced tissue edema. Despite its excellent properties, some related complications after and during the therapy have been reported. We report the case of a 47-year-old female with a thoracic wound infection after rib stabilization, managed with open surgery and VAC therapy, which was complicated by a diffuse lymphatic leakage. This is the first case described of diffuse lymphatic leakage followed by partial necrosis of the breast after continuous VAC therapy. We recommend the application of a lower pressure level of this device for complex wounds of the chest wall near the breast. PMID:26675995

  19. Detection and Identification of Bartonella Species Pathogenic for Humans by PCR Amplification Targeting the Riboflavin Synthase Gene (ribC)

    PubMed Central

    Johnson, G.; Ayers, M.; McClure, S. C. C.; Richardson, S. E.; Tellier, R.

    2003-01-01

    Several Bartonella species have now been implicated as human pathogens. The recovery of these fastidious organisms in the clinical microbiology laboratory remains difficult, and current methods are still relatively insensitive. Thus, the bartonellae are good candidates for detection by PCR. We have developed a PCR assay which uses a single primer pair targeting the riboflavin synthase gene (ribC) and detected six Bartonella species that have been implicated in human disease, B. henselae, B. quintana, B. bacilliformis, B. clarridgeiae, B. elizabethae, and B. vinsonii subsp. berkhoffii. Species identification is achieved simply by restriction enzyme digestion of the amplicon. This PCR assay appears to be specific for the Bartonella genus because it failed to amplify DNA from several other bacterial species. PMID:12624031

  20. Mutations in KIAA0586 Cause Lethal Ciliopathies Ranging from a Hydrolethalus Phenotype to Short-Rib Polydactyly Syndrome

    PubMed Central

    Alby, Caroline; Piquand, Kevin; Huber, Céline; Megarbané, André; Ichkou, Amale; Legendre, Marine; Pelluard, Fanny; Encha-Ravazi, Ferechté; Abi-Tayeh, Georges; Bessières, Bettina; El Chehadeh-Djebbar, Salima; Laurent, Nicole; Faivre, Laurence; Sztriha, László; Zombor, Melinda; Szabó, Hajnalka; Failler, Marion; Garfa-Traore, Meriem; Bole, Christine; Nitschké, Patrick; Nizon, Mathilde; Elkhartoufi, Nadia; Clerget-Darpoux, Françoise; Munnich, Arnold; Lyonnet, Stanislas; Vekemans, Michel; Saunier, Sophie; Cormier-Daire, Valérie; Attié-Bitach, Tania; Thomas, Sophie

    2015-01-01

    KIAA0586, the human ortholog of chicken TALPID3, is a centrosomal protein that is essential for primary ciliogenesis. Its disruption in animal models causes defects attributed to abnormal hedgehog signaling; these defects include polydactyly and abnormal dorsoventral patterning of the neural tube. Here, we report homozygous mutations of KIAA0586 in four families affected by lethal ciliopathies ranging from a hydrolethalus phenotype to short-rib polydactyly. We show defective ciliogenesis, as well as abnormal response to SHH-signaling activation in cells derived from affected individuals, consistent with a role of KIAA0586 in primary cilia biogenesis. Whereas centriolar maturation seemed unaffected in mutant cells, we observed an abnormal extended pattern of CEP290, a centriolar satellite protein previously associated with ciliopathies. Our data show the crucial role of KIAA0586 in human primary ciliogenesis and subsequent abnormal hedgehog signaling through abnormal GLI3 processing. Our results thus establish that KIAA0586 mutations cause lethal ciliopathies. PMID:26166481

  1. Automatic segmentation of the ribs, the vertebral column, and the spinal canal in pediatric computed tomographic images.

    PubMed

    Banik, Shantanu; Rangayyan, Rangaraj M; Boag, Graham S

    2010-06-01

    We propose methods to perform automatic identification of the rib structure, the vertebral column, and the spinal canal in computed tomographic (CT) images of pediatric patients. The segmentation processes for the rib structure and the vertebral column are initiated using multilevel thresholding and the results are refined using morphological image processing techniques with features based on radiological and anatomical prior knowledge. The Hough transform for the detection of circles is applied to a cropped edge map that includes the thoracic vertebral structure. The centers of the detected circles are used to derive the information required for the opening-by-reconstruction algorithm used to segment the spinal canal. The methods were tested on 39 CT exams of 13 patients; the results of segmentation of the vertebral column and the spinal canal were assessed quantitatively and qualitatively by comparing with segmentation performed independently by a radiologist. Using 13 CT exams of six patients, including a total of 458 slices with the vertebra from different sections of the vertebral column, the average Hausdorff distance was determined to be 3.2 mm with a standard deviation (SD) of 2.4 mm; the average mean distance to the closest point (MDCP) was 0.7 mm with SD = 0.6 mm. Quantitative analysis was also performed for the segmented spinal canal with three CT exams of three patients, including 21 slices with the spinal canal from different sections of the vertebral column; the average Hausdorff distance was 1.6 mm with SD = 0.5 mm, and the average MDCP was 0.6 mm with SD = 0.1 mm. PMID:19219504

  2. Evaluation of photon irradiation treatment upon calcium content of ribs of Wistar rats using micro-XRF

    SciTech Connect

    Parreiras Nogueira, Liebert; Barroso, Regina Cely; Pereira de Almeida, Andre; Braz, Delson; Almeida, Carlos Eduardo de; Salata, Camila; Andrade, Cherley Borba; Silva, Claudia Marcello da

    2012-05-17

    Therapeutic doses of radiation have been shown to have deleterious consequences on bone health. Among the treatment strategies used for breast cancer treatment, the most used are radiotherapy and chemotherapy. Radiotherapy may be given to destroy the cancer cells using high-dose x-rays. Protocols vary considerably, but generally whole body irradiation totals from 10 to 15 Gy, whereas local therapy totals from 40 to 70 Gy. In clinical practice, the quantitative evaluation of bone tissue relies on measurements of bone mineral density values, which are closely associated with the risk of osteoporotic fracture. Improved survivorship rates of cancer patients receiving radiotherapy increase the importance of understanding the mechanisms and long-term effects of radiation-induced bone loss. In this work, we investigated the variation on calcium distribution in ribs of female Wistar rats (Rattus norvegicus) submitted to photon irradiation with a single dose of 20 Gy. The determination of the calcium distribution was performed using synchrotron radiation microfluorescence (SR-{mu}XRF) at the X-ray Fluorescence beamline at Brazilian Synchrotron Light Laboratory (LNLS). Animals were irradiated using the linear accelerator Varian registered (CLINAC 2100) at the University Centre for Cancer Control of the State University of Rio de Janeiro (CUCC/UERJ). The total dose delivered was 20 Gy. The animals were about three months old and weighting about 200g. They were distributed into two groups (seven per group): control (did not receive any treatment) and irradiated (submitted to irradiation procedure) groups. Results showed that calcium content decreased within the dorsal ribs of rats submitted to radiotherapy in comparison to the control group.

  3. Evaluation of photon irradiation treatment upon calcium content of ribs of Wistar rats using micro-XRF

    NASA Astrophysics Data System (ADS)

    Nogueira, Liebert Parreiras; Barroso, Regina Cély; de Almeida, André Pereira; Braz, Delson; de Almeida, Carlos Eduardo; Salata, Camila; Andrade, Cherley Borba; da Silva, Claudia Marcello

    2012-05-01

    Therapeutic doses of radiation have been shown to have deleterious consequences on bone health. Among the treatment strategies used for breast cancer treatment, the most used are radiotherapy and chemotherapy. Radiotherapy may be given to destroy the cancer cells using high-dose x-rays. Protocols vary considerably, but generally whole body irradiation totals from 10 to 15 Gy, whereas local therapy totals from 40 to 70 Gy. In clinical practice, the quantitative evaluation of bone tissue relies on measurements of bone mineral density values, which are closely associated with the risk of osteoporotic fracture. Improved survivorship rates of cancer patients receiving radiotherapy increase the importance of understanding the mechanisms and long-term effects of radiation-induced bone loss. In this work, we investigated the variation on calcium distribution in ribs of female Wistar rats (Rattus norvegicus) submitted to photon irradiation with a single dose of 20 Gy. The determination of the calcium distribution was performed using synchrotron radiation microfluorescence (SR-μXRF) at the X-ray Fluorescence beamline at Brazilian Synchrotron Light Laboratory (LNLS). Animals were irradiated using the linear accelerator Varian® (CLINAC 2100) at the University Centre for Cancer Control of the State University of Rio de Janeiro (CUCC/UERJ). The total dose delivered was 20 Gy. The animals were about three months old and weighting about 200g. They were distributed into two groups (seven per group): control (did not receive any treatment) and irradiated (submitted to irradiation procedure) groups. Results showed that calcium content decreased within the dorsal ribs of rats submitted to radiotherapy in comparison to the control group.

  4. Diagnostics of basal conditions - the formation of extensive zones of surface ribs in ice-sheets and streams

    NASA Astrophysics Data System (ADS)

    Hindmarsh, Richard C. A.; Sergienko, Olga V.; Creyts, Timothy T.

    2015-04-01

    Most if not all current predictions of the evolution of ice-streams to changes induced by global change assume static basal conditions. This is a result of current restrictions in the remote sensing of the ice-sheet basal physical environment, which cannot resolve the small-scale phenomena believed to control the basal traction. The search therefore is on for observable structures or features that are the result of the operation of basal processes. Any successful theory of ice-sheet basal processes would need to be able to explain such phenomena associated with or caused by special properties of the basal environment. We present one class of these phenomena, and also present tentative hypotheses as to their formation. Using recent high-resolution observations of the Antarctic and Greenland ice sheets topography, the computed driving stress and the inferred basal traction reveal broad-scale organization in 5-20 km band-like patterns in both quantities. The similarity of patterns on the Greenland and Antarctic ice sheets suggests that the flow of ice sheets is controlled by the same fundamental processes operating at their base, which control ice sheet sliding and are highly variable on relatively short spatial and temporal scales. The formation mechanism for these bands contains information about the operation of the sub-glacial system. There are three possible, non-exclusive causes of these ribs which we examine from a theoretical and evidential point-of-view (i) They are the surface response to similar bands in the basal topography, whose regularity would equally require an explanation in terms of basal processes. (ii) They are translating surface waves in the ice, supported by membrane stress gradients rather than by gradients in the basal resistance. (iii) The ribs are due to the development of a band-like structure in the basal shear stress distribution that is the result of a pattern-forming instability in sub-glacial till and water flow, perhaps related to

  5. NUCLEAR ASTROPHYSICS PROJECT WITH A NEW LOW-ENERGY RIB SEPARATOR CRIB:. Study of a Critical Stellar Reaction 15O(α,γ)19Ne

    NASA Astrophysics Data System (ADS)

    Kubono, S.; Michimasa, S.; Teranishi, T.; Yanagisawa, Y.; Fulop, Z.; Liu, X.; Kumagai, K.; Abe, K.; Yun, C. C.; Watanabe, S.; Yamazaki, N.; Ohshiro, Y.; Kurokawa, M.; Strasser, P.; Hahn, K. I.; Kishida, T.; Imai, N.; Kato, S.; Fuchi, Y.; Tanaka, M. H.

    2003-04-01

    One of the critical stellar reactions for the onset of explosive hydrogen burning, 15O(α,γ)19Ne, is discussed with our recent experimental effort and a new possibility in our new RIB project. This reaction was investigated experimentally by indirect methods. Single particle nature of the threshold states was studied by the analog reactions, (d,t) and (d,3He) on 20Ne. The α-branching ratios for some states were also measured by a coincidence measurement of a triton and α from 19F(3He,t)19Ne*(α)15O(g.s.). Experimental plan for the problem was also discussed that uses a new low-energy RIB facility at CNS, called CRIB, which will come into operation soon.

  6. Effects of consecutive application of stretching, Schroth, and strengthening exercises on Cobb’s angle and the rib hump in an adult with idiopathic scoliosis

    PubMed Central

    Yang, Jae-Man; Lee, Jung-Hoon; Lee, Dae-Hee

    2015-01-01

    [Purpose] To report the effects of consecutive application of stretching, Schroth, and strengthening exercises in an adult with idiopathic scoliosis. [Subject] A 26-year-old woman with idiopathic scoliosis, Cobb’s angle of 20.51°, and back pain. [Methods] The exercise program consisted of 3 sessions: 10 minutes of stretching exercises, 20 minutes of Schroth exercises, and 10 minutes of strengthening exercises. This program was implemented 3 times a week, for 8 weeks. [Results] The thoracic Cobb’s angle decreased from 20.51° to 16.35°, and the rib hump decreased from 15° to 9°. [Conclusion] Consecutive application of stretching, Schroth, and strengthening exercises may help reduce Cobb’s angle and the rib hump in adults with idiopathic scoliosis. PMID:26355577

  7. Chest Wall Volume Receiving >30 Gy Predicts Risk of Severe Pain and/or Rib Fracture After Lung Stereotactic Body Radiotherapy

    SciTech Connect

    Dunlap, Neal E.; Cai, Jing; Biedermann, Gregory B.; Yang, Wensha; Benedict, Stanley H.; Sheng Ke; Schefter, Tracey E.; Kavanagh, Brian D.; Larner, James M.

    2010-03-01

    Purpose: To identify the dose-volume parameters that predict the risk of chest wall (CW) pain and/or rib fracture after lung stereotactic body radiotherapy. Methods and Materials: From a combined, larger multi-institution experience, 60 consecutive patients treated with three to five fractions of stereotactic body radiotherapy for primary or metastatic peripheral lung lesions were reviewed. CW pain was assessed using the Common Toxicity Criteria for pain. Peripheral lung lesions were defined as those located within 2.5 cm of the CW. A minimal point dose of 20 Gy to the CW was required. The CW volume receiving >=20, >=30, >=40, >=50, and >=60 Gy was determined and related to the risk of CW toxicity. Results: Of the 60 patients, 17 experienced Grade 3 CW pain and five rib fractures. The median interval to the onset of severe pain and/or fracture was 7.1 months. The risk of CW toxicity was fitted to the median effective concentration dose-response model. The CW volume receiving 30 Gy best predicted the risk of severe CW pain and/or rib fracture (R{sup 2} = 0.9552). A volume threshold of 30 cm{sup 3} was observed before severe pain and/or rib fracture was reported. A 30% risk of developing severe CW toxicity correlated with a CW volume of 35 cm{sup 3} receiving 30 Gy. Conclusion: The development of CW toxicity is clinically relevant, and the CW should be considered an organ at risk in treatment planning. The CW volume receiving 30 Gy in three to five fractions should be limited to <30 cm{sup 3}, if possible, to reduce the risk of toxicity without compromising tumor coverage.

  8. Ionization efficiency and effusive delay time characterization of high temperature target-ion sources for RIB generation

    SciTech Connect

    Welton, R.F.; Alton, G.D.; Murray, S.N.; Cui, B.

    1996-12-01

    Ion sources for radioactive ion beam (RIB) generation must efficiently ionize short-lived-radioactive nuclei released from on-line targets with minimal delay times. Delay times attributable to interactions between chemically active species and surfaces of the vapor transport system which are long compared to the half-life of the desired radioactive atom and/or low ionization efficiency of the target/ion source (TIS) will result in a severe reduction of the RM intensity available for research. We have developed complementary off-line techniques for directly measuring both effusive delay times and ionization efficiencies for chemically active species in high temperature TISs using only the stable complements of the radioactive element of interest. Equipment, designed and developed for these measurements, include: a high-temperature Ta valve; a differentially cooled injection nozzle; and a gaseous flow measurement and control system. These techniques are employed in a systematic investigation of fluorine transport and ionization in an electron-beam-plasma target/ion source (EBPTIS) designed for initial use at the Holifield Radioactive Ion Beam Facility (HRIBF).

  9. Slumped glass optics with interfacing ribs for high angular resolution x-ray astronomy: a progress report

    NASA Astrophysics Data System (ADS)

    Civitani, M.; Basso, S.; Brizzolari, C.; Ghigo, M.; Pareschi, G.; Salmaso, B.; Spiga, D.; Vecchi, G.; Breunig, E.; Burwitz, V.; Hartner, G. D.; Menz, B.

    2015-09-01

    The Slumped Glass Optics technology, developed at INAF/OAB since a few years, is becoming a competitive solution for the realization of the future X-ray telescopes with a very large collecting area, as e.g. the proposed Athena, with more than 2 m2 effective area at 1 keV and with a high angular resolution (5'' HEW). The developed technique is based on modular elements, named X-ray Optical Units (XOUs), made of several layers of thin foils of glass, previously formed by direct hot slumping in cylindrical configuration, and then stacked in a Wolter-I configuration, through interfacing ribs. The achievable global angular resolution of the optics relies on the surface shape accuracy of the slumped foils, on the smoothness of the mirror surfaces and on the correct integration and co-alignment of the mirror segments achieved with a dedicated Integration Machine (IMA). In this paper we provide an update of the project development, reporting on the last results achieved. In particular, we will present the results obtained with full illumination X-ray tests for the last developed prototypes.

  10. Opportunities with the K600 Magnetic Spectrometer During Phase 1 of the iThemba LABS RIB Project

    NASA Astrophysics Data System (ADS)

    Neveling, R.

    2015-11-01

    Measurements of hadronic scattering and reactions at zero degrees is highly sought after because of its selectivity to excitations with low angular momentum transfer. High energy resolution measurements of this nature can only be performed at a few facilities worldwide, including iThemba LABS. Such measurements present significant experimental challenges due to the small difference in magnetic rigidity between the projectiles and the particles of interest. Hence a substantial amount of time and effort is required to achieve suitably stable and clean beam conditions before any measurement can be attempted. This results in large inefficiencies in beam usage and data collection under the current beam schedule at iThemba LABS, severely limiting the scope of research that can be performed with this facility. However, it is foreseen that during the first phase of the radioactive-ion beam (RIB) project at iThemba LABS a significant amount of beam-time will become available for stable beam nuclear physics research. It is imperative to plan ahead to ensure optimum utilization of beam-time during this period while taking advantage of the existing unique facilities at iThemba LABS. Potential projects that can make use of the zero-degree capabilities of the K600 magnetic spectrometer are discussed.

  11. Effects of low and high salinity regimes on seasonal gametogenesis of the ribbed mussel Geukensia granosissima in coastal Louisiana, USA

    USGS Publications Warehouse

    Honig, Aaron; LaPeyre, Megan K.; Supan, John

    2014-01-01

    Benthic intertidal bivalves play an essential role in estuarine ecosystems by contributing to habitat provision, water filtration, and host vegetation productivity. As such, ecosystem level changes that impact population distributions and persistence of local bivalve populations may have large ecosystem level consequences, making it important to better understand the population ecology of native bivalves. In order to determine potential impacts of shifting salinity and temperature regimes along the northern Gulf of Mexico, the seasonal timing of gametogenesis in the Gulf estuarine ribbed mussel, Geukensia granossisima, was examined across a salinity gradient in southeastern Louisiana, from July 2011 through October 2012. Ten mussels were randomly sampled monthly from low (~ 5) and high (~25) salinity marsh sites in southeastern Louisiana, and histologically processed to determine the seasonal progression of gametogenesis. Peak ripeness occurred at both sites between April and September, was positively correlated with temperature, and coincided with seasonal shifts in salinity. Mussels located in lower salinity waters demonstrated a shorter period of gametogenesis, and lower rates of ripeness indicating that changes in salinity regimes may impact long-term population dynamics.

  12. Flow and heat transfer in an L-shaped cooling passage with ribs and pin fins for the trailing edge of a gas-turbine vane and blade

    NASA Astrophysics Data System (ADS)

    Pardeshi, Irsha

    Efficient and effective cooling of the trailing edges of gas-turbine vanes and blades is challenging because there is very little space to work with. In this study, CFD simulations based on steady RANS closed by the shear-stress transport turbulence model were performed to study the flow and heat transfer in an L-shaped duct for the trailing edge under two operating conditions. One operating condition, referred to as the laboratory condition, where experimental measurements were made, has a Reynolds number at the duct inlet of ReD = 15,000, coolant inlet temperature of Tinlet = 300 K, wall temperature of Twall = 335 K, a back pressure of Pb = 1 atm. When rotating, the angular speed was O = 1,000 rpm. The other condition, referred to as the engine-relevant condition, has Re D = 150,000 at the duct inlet, Tinlet = 673 K, Twall = 1,173 K, and Pb = 25 atm. When rotating, O was 3,600 rpm. The objective is to understand the nature of the flow and heat transfer in an L-shaped cooling passage for the trailing edge that has a combination of ribs and pin fins under rotating and non-rotating conditions with focus on how pin fins and ribs distribute the flow throughout the passage and to understand what features of the flow and heat transfer can or cannot be extrapolated from the laboratory to the engine-relevant operating conditions. When there is no rotation, results obtained show that for both operating conditions, the pin fins minimized the size of the separation bubble when the flow exits the inlet duct into the expanded portion of the L-shaped duct. The size of the separation bubble at the tip of the L-shaped duct created by the adverse pressure gradient is quite large for the laboratory condition and relatively small for the engine condition. Each rib was found to create two sets of recirculating flows, one just upstream of the rib because of the adverse pressure gradient induced by the rib and one just downstream of the rib because of flow separation from a sharp edge

  13. Modeling and Simulation of Turbulent Flows through a Solar Air Heater Having Square-Sectioned Transverse Rib Roughness on the Absorber Plate

    PubMed Central

    Yadav, Anil Singh; Bhagoria, J. L.

    2013-01-01

    Solar air heater is a type of heat exchanger which transforms solar radiation into heat energy. The thermal performance of conventional solar air heater has been found to be poor because of the low convective heat transfer coefficient from the absorber plate to the air. Use of artificial roughness on a surface is an effective technique to enhance the rate of heat transfer. A CFD-based investigation of turbulent flow through a solar air heater roughened with square-sectioned transverse rib roughness has been performed. Three different values of rib-pitch (P) and rib-height (e) have been taken such that the relative roughness pitch (P/e = 14.29) remains constant. The relative roughness height, e/D, varies from 0.021 to 0.06, and the Reynolds number, Re, varies from 3800 to 18,000. The results predicted by CFD show that the average heat transfer, average flow friction, and thermohydraulic performance parameter are strongly dependent on the relative roughness height. A maximum value of thermohydraulic performance parameter has been found to be 1.8 for the range of parameters investigated. Comparisons with previously published work have been performed and found to be in excellent agreement. PMID:24222752

  14. Experimental investigation of the effect of variously-shaped ribs on local heat transfer on the outer wall of the turning portion of a U-channel inside solar air heater

    NASA Astrophysics Data System (ADS)

    Salameh, Tareq; Alami, Abdul Hai; Sunden, Bengt

    2016-03-01

    In the present work, an experimental investigation of convective heat transfer and pressure drop was carried out for the turning portion of a U-channel where the outer wall was equipped with ribs. The shape of the ribs was varied. The investigation aims to give guidelines for improving the thermo-hydraulic performance of a solar air heater at the turning portion of a U-channel. Both the U-channel and the ribs were made in acrylic material to allow optical access for measuring the surface temperature by using a high-resolution technique based on narrow band thermochromic liquid crystals (TLC R35C5 W) and a CCD camera placed to face the turning portion of the U-channel. The uncertainties were estimated to 5 and 7 % for the Nusselt number and friction factor, respectively. The pressure drop was approximately the same for all the considered shapes of the ribs while the dimpled rib case gave the highest heat transfer coefficient while the grooved rib presented the highest performance index.

  15. Feasibility of Coupling Between a Single-Mode Elliptical-Core Fiber and a Single Mode Rib Waveguide Over Temperature. Ph.D. Thesis - Akron Univ., Aug. 1995

    NASA Technical Reports Server (NTRS)

    Tuma, Margaret L.

    1995-01-01

    To determine the feasibility of coupling the output of an optical fiber to a rib waveguide in a temperature environment ranging from 20 C to 300 C, a theoretical calculation of the coupling efficiency between the two was investigated. This is a significant problem which needs to be addressed to determine whether an integrated optic device can function in a harsh temperature environment. Because the behavior of the integrated-optic device is polarization sensitive, a polarization-preserving optic fiber, via its elliptical core, was used to couple light with a known polarization into the device. To couple light energy efficiently from an optical fiber into a channel waveguide, the design of both components should provide for well-matched electric field profiles. The rib waveguide analyzed was the light input channel of an integrated-optic pressure sensor. Due to the complex geometry of the rib waveguide, there is no analytical solution to the wave equation for the guided modes. Approximation or numerical techniques must be utilized to determine the propagation constants and field patterns of the guide. In this study, three solution methods were used to determine the field profiles of both the fiber and guide: the effective-index method (EIM), Marcatili's approximation, and a Fourier method. These methods were utilized independently to calculate the electric field profile of a rib channel waveguide and elliptical fiber at two temperatures, 20 C and 300 C. These temperatures were chosen to represent a nominal and a high temperature that the device would experience. Using the electric field profile calculated from each method, the theoretical coupling efficiency between the single-mode optical fiber and rib waveguide was calculated using the overlap integral and results of the techniques compared. Initially, perfect alignment was assumed and the coupling efficiency calculated. Then, the coupling efficiency calculation was repeated for a range of transverse offsets at

  16. Experimental investigation of inclination effect on subcritical and supercritical water flows heat transfer in an internally ribbed tube

    NASA Astrophysics Data System (ADS)

    Taklifi, Alireza; Akhavan-Behabadi, Mohammad Ali; Hanafizadeh, Pedram; Aliabadi, Abbas

    2016-06-01

    The effect of various inclination angles on heat transfer of water at subcritical and supercritical operating pressures is investigated experimentally. The test section was a SA213T12 steel six-headed internally ribbed tube with minimum inner diameter of 19.5 mm. The operating test pressures were 15, 21.5, 22.5, 25 and 28 MPa, the mass flux was 800 kg/m2 s and the heat flux was 400 kW/m2. To keep the mass flux to heat flux ratio equal to 2 kg/kJ. These operating conditions covered subcritical, near critical and supercritical water flows and also refers to low mass flux conditions. The inclination angles were 5, 20, 30, 45 and 90 (vertical) degrees respecting to horizontal plane. The heat flux was kept constant along the test tube by controlling of electric heating. As a result the inner wall temperature and convective heat transfer coefficient variations with respect to heated length and bulk enthalpy of fluid were considered in order to study the heat transfer characteristics of various flows at different inclinations. The corresponding correlation for heat transfer coefficient was developed which is applicable for wide range of inclination angles. The heat transfer enhancement was obvious for inclination angles other than 90°, however, this effect was more obvious in 5° and 20° in some operating conditions. It was also concluded that the effect of inclination on heat transfer of water was more considerable in subcritical flow conditions than supercritical ones. Also, it was observed that angle of 20° seems to be the best for subcritical flows from heat transfer point of view, but for supercritical flows 5 or 45 seem to be more advantageous. These differences could be related to different heat transfer mechanisms of subcritical and supercritical flows.

  17. Genome-wide study refines the quantitative trait locus for number of ribs in a Large White × Minzhu intercross pig population and reveals a new candidate gene.

    PubMed

    Zhang, Long-Chao; Yue, Jing-Wei; Pu, Lei; Wang, Li-Gang; Liu, Xin; Liang, Jing; Yan, Hua; Zhao, Ke-Bin; Li, Na; Shi, Hui-Bi; Zhang, Yue-Bo; Wang, Li-Xian

    2016-10-01

    In China, sparerib is one of the most valuable parts of the pork carcass. As a result, candidate gene mining for number of ribs has become an interesting study focus. To examine the genetic basis for this major trait, we genotyped 596 individuals from an F2 Large White × Minzhu intercross pig population using the PorcineSNP60 Genotyping BeadChip. The genome-wide association study identified a locus for number of ribs in a 2.38-Mb region on Sus scrofa chromosome 7 (SSC7 of Sus scrofa genome assembly, Sscrofa10.2). We identified the top significant SNP ASGA0035536, which explained 16.51 % of the phenotypic variance. A previously reported candidate causal mutation (g.19034 A>C) in vertebrae development-associated gene VRTN explained 8.79 % of the phenotypic variation on number of ribs and had a much lower effect than ASGA0035536. Haplotype sharing analysis in F1 boars localized the rib number QTL to a 951-kb interval on SSC7. This interval encompassed 17 annotated genes in Sscrofa10.2, including the previously reported VRTN candidate gene. Of the 17 candidate genes, LTBP2, which encodes a latent transforming growth factor beta binding protein, was previously reported to indirectly regulate the activity of growth differentiation factor Gdf11, which has been shown to increase the number of ribs in knock-out mice. Thus, we propose LTBP2 as a good new candidate gene for number of ribs in the pig population. This finding advances our understanding of the genetic architecture of rib number in pigs. PMID:27307002

  18. Torsion and Bending in the Neck and Tail of Sauropod Dinosaurs and the Function of Cervical Ribs: Insights from Functional Morphology and Biomechanics

    PubMed Central

    Preuschoft, Holger; Klein, Nicole

    2013-01-01

    The long necks of sauropods have been subject to many studies regarding their posture and flexibility. Length of the neck varies among groups. Here, we investigate neck posture and morphology in several clades from a mechanical viewpoint. Emphasis is put on comparing sauropod necks and tails with structures in living archosaurs and mammals. Differences in the use made of necks and tails lead to clear-cut differences in the mechanical loads occurring in the same models. Ways of sustaining loads are identified by theoretical considerations. If the observed skeletal structures are suited to resist the estimated loading in a particular posture, this concordance is taken as an argument that this posture or movement was of importance during the life of the individual. Apart from the often-discussed bending in side view, we analyze the often overlooked torsion. Because torsional stresses in a homogenous element concentrate near the periphery, a cylindrical cross section gives greatest strength, and the direction of forces is oblique. In a vertebrate neck, during e.g. shaking the head and twisting the neck, oblique muscles, like the mm. scaleni, if activated unilaterally initiate movement, counterbalance the torsional moments and keep the joints between neck vertebrae in equilibrium. If activated bilaterally, these muscles keep the neck balanced in an energy-saving upright posture. The tendons of the mm. scaleni may have ossified as cervical ribs The long cervical ribs in brachiosaurids and mamenchisaurids seem to have limited flexibility, whereas the shorter cervical ribs in Diplodocidae allowed free movement. The tails of sauropods do not show pronounced adaptation to torsion, and seem to have been carried more or less in a horizontal, extended posture. In this respect, sauropod tails resemble the necks of herbivorous cursorial mammals. These analyses provide an improved understanding of neck use that will be extended to other sauropods in subsequent studies. PMID

  19. Abdominal Organ Location, Morphology, and Rib Coverage for the 5th, 50th, and 95th Percentile Males and Females in the Supine and Seated Posture using Multi-Modality Imaging

    PubMed Central

    Hayes, Ashley R.; Gayzik, F. Scott; Moreno, Daniel P.; Martin, R. Shayn; Stitzel, Joel D.

    2013-01-01

    The purpose of this study was to use data from a multi-modality image set of males and females representing the 5th, 50th, and 95th percentile (n=6) to examine abdominal organ location, morphology, and rib coverage variations between supine and seated postures. Medical images were acquired from volunteers in three image modalities including Computed Tomography (CT), Magnetic Resonance Imaging (MRI), and upright MRI (uMRI). A manual and semi-automated segmentation method was used to acquire data and a registration technique was employed to conduct a comparative analysis between abdominal organs (liver, spleen, and kidneys) in both postures. Location of abdominal organs, defined by center of gravity movement, varied between postures and was found to be significant (p=0.002 to p=0.04) in multiple directions for each organ. In addition, morphology changes, including compression and expansion, were seen in each organ as a result of postural changes. Rib coverage, defined as the projected area of the ribs onto the abdominal organs, was measured in frontal, lateral, and posterior projections, and also varied between postures. A significant change in rib coverage between postures was measured for the spleen and right kidney (p=0.03 and p=0.02). The results indicate that posture affects the location, morphology and rib coverage area of abdominal organs and these implications should be noted in computational modeling efforts focused on a seated posture. PMID:24406951

  20. Comparison of the Analgesic Effect of Intravenous Acetaminophen and Morphine Sulfate in Rib Fracture; a Randomized Double-Blind Clinical Trial

    PubMed Central

    Esmailian, Mehrdad; Moshiri, Roshanak; Zamani, Majid

    2015-01-01

    Introduction: Rib fracture is one of the common causes of trauma disabilities in many events and the outcome of these patients are very extensive from temporary pain management to long-term significant disability. Control and management of the pain in such patients is one of the most important challenges in emergency departments. Thus, the aim of the present study was assessing the efficacy of IV acetaminophen in pain control of patients with rib fracture. Methods: In this double-blind clinical trial, 54 patients over 18 years of age, referred to two educational hospitals with rib fracture, were entered. Patients were randomly categorized in two groups of morphine sulfate (0.1 milligram per kilogram of body weight) and IV acetaminophen (1gram), as single-dose infused in 100 cc normal saline. The pain severity was measured by numeric rating scale (NRS) on arrival and 30 minutes after drug administration. At least three scores reduction was reported as therapeutic success. Results: The mean and standard deviation of patients’ age was 41.2 ± 14.1 years. There is no difference in gender (p=0.24) and age frequency (p=0.77) between groups. 30 minutes after drug administration the mean of pain severity were 5.5 ± 2.3 and 4.9 ± 1.7 in morphine and acetaminophen groups, respectively (p=0.23). Success rate in morphine and acetaminophen groups were 58.6% (95% Cl: 39.6-77.7) and 80% (95% Cl: 63.2-96.7), respectively, (p=0.09). Only 3 (5.6%) patients had dizziness (p=0.44) and other effects were not seen in any of patients. Conclusion: The findings of the present study shows that intravenous acetaminophen and morphine have the same therapeutic value in relieving the pain of rib fracture. The success rate after 30 minutes drug administration were 80% and 58.6% in acetaminophen and morphine groups, respectively. Presentation of side effects was similar in both groups. PMID:26495393

  1. Equivalent modulus method for finite element simulation of the sound absorption of anechoic coating backed with orthogonally rib-stiffened plate

    NASA Astrophysics Data System (ADS)

    Jin, Zhongkun; Yin, Yao; Liu, Bilong

    2016-03-01

    The finite element method is often used to investigate the sound absorption of anechoic coating backed with orthogonally rib-stiffened plate. Since the anechoic coating contains cavities, the number of grid nodes of a periodic unit cell is usually large. An equivalent modulus method is proposed to reduce the large amount of nodes by calculating an equivalent homogeneous layer. Applications of this method in several models show that the method can well predict the sound absorption coefficient of such structure in a wide frequency range. Based on the simulation results, the sound absorption performance of such structure and the influences of different backings on the first absorption peak are also discussed.

  2. In patients with acute flail chest does surgical rib fixation improve outcomes in terms of morbidity and mortality?

    PubMed

    Schulte, Katharina; Whitaker, Donald; Attia, Rizwan

    2016-08-01

    A best evidence topic in cardiothoracic surgery was written according to a structured protocol. The question addressed was: In patients with acute flail chest does surgical rib fixation improve outcomes in terms of morbidity and mortality? Using the reported search criteria, 137 papers were found. Of these, 11 papers (N = 1712) represent the best evidence to answer the clinical question, and include one meta-analysis, two randomized, controlled trials (RCTs), five retrospective cohort studies and two case-control series. In-hospital mortality was lower for the surgical group in the meta-analysis [n = 582, odds ratio (OR) 0.31 (0.20-0.48), risk difference (RD) 0.19 (0.13-0.26), number needed to treat (NNT) 5] as well as significant decreases in ventilator days [mean 8 days, 95% confidence interval (CI) 5-10 days] and intensive care unit stay (mean 5 days, 95% CI 2-8 days). A reduction was found for septicaemia [n = 345, OR 0.36 (0.19-0.71), RD 0.14 (0.56-0.23), NNT 7], pneumonia [n = 616, OR 0.18 (0.11-0.32), RD 0.31 (0.21-0.41), NNT 3, P = 0.001], tracheostomy (OR 0.06, 95% CI 0.02-0.20) and chest wall deformity [n = 228, OR 0.11 (0.02-0.60), RD 0.30 (0.00-0.60), NNT 3]. Eight studies (n = 1015) had a shorter duration of mechanical ventilation following surgery. A reduction in intensive care unit stay was demonstrated in four papers (n = 389, 3.1-9.0 days), whereas a further three papers described a reduction in the duration of hospitalization (n = 489, 4-10.6 days). Three studies (n = 166) showed a lower risk for tracheostomy. One retrospective cohort study estimated lower total treatment costs in surgically treated patients ($32 300 vs $37 100) although not statistically significant. One retrospective case-control study described a lower risk for reintubation (n = 50, P = 0.034) and home oxygen requirements (n = 50, P = 0.034). One cohort study showed a better APACHE II score 14 days after trauma in the surgical group (P = 0.02). Surgical stabilization of flail

  3. Rib fracture - aftercare

    MedlinePlus

    Apply an ice pack 20 minutes of every hour you are awake for the first 2 days, then 10 to 20 minutes ... needed to reduce pain and swelling. Wrap the ice pack in a cloth before applying to the injured ...

  4. Rib cage pain

    MedlinePlus

    ... not cause the pain in someone who has pleurisy (swelling of the lining of the lungs) or ... Inflammation of cartilage near the breastbone ( costochondritis ) Osteoporosis Pleurisy (the pain is worse when breathing deeply) Home ...

  5. Mitochondrial DNA preservation across 3000-year-old northern fur seal ribs is not related to bone density: Implications for forensic investigations.

    PubMed

    Barta, Jodi Lynn; Monroe, Cara; Crockford, Susan J; Kemp, Brian M

    2014-06-01

    While recent forensic research has focused on determining which skeletal elements are superior in their preservation of DNA over the long term, little focus has been placed on measuring intra-element variation. Moreover, there is a general belief that dense (cortical) bone material will contain better-preserved DNA than does spongy (cancellous) bone. To address these ideas, quantitative PCR was used to estimate the degree of mitochondrial DNA (mtDNA) preservation variance across sections of 19 northern fur seal ribs (Callorhinus ursinus) that date to ∼3000 years before present. Further, we developed a measure called the "density index" that was used to gauge the relative densities of the rib sections studied here to determine if density was an appropriate predictor of preservation. The average preservation among the samples was significantly different (ANOVA, p=1.9×10(-9)) with only 15% of the total variance observed within samples. However, 12 of the 19 specimens (∼63.2%) exhibited at least an order of magnitude difference in mtDNA preservation across the whole. Regression of the amount of mtDNA extracted per gram of bone material against the density index of the bone from which it was extracted demonstrates no relationship between these variables (R(2)=0.03, p=0.28). PMID:24709029

  6. Design of a High-Performance Micro Integrated Surface Plasmon Resonance Sensor Based on Silicon-On-Insulator Rib Waveguide Array.

    PubMed

    Yuan, Dengpeng; Dong, Ying; Liu, Yujin; Li, Tianjian

    2015-01-01

    Based on silicon-on-insulator (SOI) rib waveguide with large cross-section, a micro integrated surface plasmon resonance (SPR) biochemical sensor platform is proposed. SPR is excited at the deeply etched facet of the bend waveguide by the guiding mode and a bimetallic configuration is employed. With the advantages of SOI rib waveguide and the silicon microfabrication technology, an array of the SPR sensors can be composed to implement wavelength interrogation of the sensors' output signal, so the spectrometer or other bulky and expensive equipment are not necessary, which enables the SPR sensor to realize the miniaturization and integration of the entire sensing system. The performances of the SPR sensor element are verified by using the two-dimensional finite-different time-domain method. The parameters of the sensor element and the array are optimized for the achievement of high performance for biochemical sensing application. As a typical example, a single bimetallic SPR sensor with 3 nm Au over 32 nm Al possesses a high sensitivity of 3.968 × 104 nm/RIU, a detection-accuracy of 14.7 μm(-1). For a uniparted SPR sensor, it can achieve a detection limit of 5.04 × 10(-7) RIU. With the relative power measurement accuracy of 0.01 dB, the refractive index variation of 1.14 × 10(-5) RIU can be detected by the SPR sensor array. PMID:26193277

  7. Design of a High-Performance Micro Integrated Surface Plasmon Resonance Sensor Based on Silicon-On-Insulator Rib Waveguide Array

    PubMed Central

    Yuan, Dengpeng; Dong, Ying; Liu, Yujin; Li, Tianjian

    2015-01-01

    Based on silicon-on-insulator (SOI) rib waveguide with large cross-section, a micro integrated surface plasmon resonance (SPR) biochemical sensor platform is proposed. SPR is excited at the deeply etched facet of the bend waveguide by the guiding mode and a bimetallic configuration is employed. With the advantages of SOI rib waveguide and the silicon microfabrication technology, an array of the SPR sensors can be composed to implement wavelength interrogation of the sensors’ output signal, so the spectrometer or other bulky and expensive equipment are not necessary, which enables the SPR sensor to realize the miniaturization and integration of the entire sensing system. The performances of the SPR sensor element are verified by using the two-dimensional finite-different time-domain method. The parameters of the sensor element and the array are optimized for the achievement of high performance for biochemical sensing application. As a typical example, a single bimetallic SPR sensor with 3 nm Au over 32 nm Al possesses a high sensitivity of 3.968 × 104 nm/RIU, a detection-accuracy of 14.7 μm−1. For a uniparted SPR sensor, it can achieve a detection limit of 5.04 × 10−7 RIU. With the relative power measurement accuracy of 0.01 dB, the refractive index variation of 1.14 × 10−5 RIU can be detected by the SPR sensor array. PMID:26193277

  8. On-chip beamsplitter operation on single photons from quasi-resonantly excited quantum dots embedded in GaAs rib waveguides

    SciTech Connect

    Rengstl, U.; Schwartz, M.; Herzog, T.; Hargart, F.; Paul, M.; Portalupi, S. L.; Jetter, M.; Michler, P.

    2015-07-13

    We present an on-chip beamsplitter operating on a single-photon level by means of a quasi-resonantly driven InGaAs/GaAs quantum dot. The single photons are guided by rib waveguides and split into two arms by an evanescent field coupler. Although the waveguides themselves support the fundamental TE and TM modes, the measured degree of polarization (∼90%) reveals the main excitation and propagation of the TE mode. We observe the preserved single-photon nature of a quasi-resonantly excited quantum dot by performing a cross-correlation measurement on the two output arms of the beamsplitter. Additionally, the same quantum dot is investigated under resonant excitation, where the same splitting ratio is observed. An autocorrelation measurement with an off-chip beamsplitter on a single output arm reveal the single-photon nature after evanescent coupling inside the on-chip splitter. Due to their robustness, adjustable splitting ratio, and their easy implementation, rib waveguide beamsplitters with embedded quantum dots provide a promising step towards fully integrated quantum circuits.

  9. Experimental study of heat transfer enhancement in solar air heater with different angle of attack of V-down continuous ribs

    NASA Astrophysics Data System (ADS)

    Istanto, Tri; Danardono, Dominicus; Yaningsih, Indri; Wijayanta, Agung Tri

    2016-06-01

    In this paper, an experimental study on the effect of angle attack in V-down continuous ribs on heat transfer and friction factor in an artificially roughened air heater duct is presented. The electric heater with a constant heat flux as a simulation of the indoor testing solar air heater is used to heat the roughened part of rectangular duct while other parts were insulated. The system and operating conditions were used to decide the range of parameters for the study. The ratio of the width to height of the duct (W/H) was 12, the relative roughness pitch (p/e) was 10, the relative roughness height (e/Dh) was 0.033 and the angle of attack of flow (α) was 30-80°. The air flow rate corresponded to Reynolds number between 3500 -10,000. The result of heat transfer and friction factor had been compared to those for smooth duct under similar flow and thermal boundary condition. The thermo-hydraulic performance also had been considered. As a result, the maximum enhancement of Nusselt number (Nu) and friction factor(f) were 2.34 and 2.45 times, respectively. For each variation of angle attack of flow, the thermo-hydraulic performance has been compared and the result shows that a V-down continuous rib with the angle of attack of flow as 60° gave the best thermo-hydraulic performance.

  10. Rib lesions in skeletons from early neolithic sites in Central Germany: on the trail of tuberculosis at the onset of agriculture.

    PubMed

    Nicklisch, Nicole; Maixner, Frank; Ganslmeier, Robert; Friederich, Susanne; Dresely, Veit; Meller, Harald; Zink, Albert; Alt, Kurt W

    2012-11-01

    As an infectious disease, tuberculosis (TB) is one of the major causes of death worldwide. Paleopathological and paleomicrobiological studies indicate a long standing association of the causative agent Mycobacterium tuberculosis and its human host. Since the occurrence and the epidemic spread of this pathogen seem to be closely linked to social and biological factors, it is of particular interest to understand better the role of TB during periods of social and nutritional change such as the Neolithic. In this study, 118 individuals from three sites in Saxony-Anhalt (Germany) dating to the Linear Pottery Culture (5400-4800 BC) were examined macroscopically to identify TB related bone lesions. In two individuals, Pott's disease was detected. In addition, periosteal reactions of varying degrees and frequency were observed mainly along the neck of the ribs in 6.5% (2/31) of subadults and 35.1% (20/57) of adults, with one site standing out markedly. Rib lesions, however, are not specific indicators of TB as they can also be caused by other diseases; so additional investigations were undertaken using histology and micro-CT scans to say more about the disease process. Supplementary molecular analyses indicate the presence of pathogens belonging to the Mycobacterium tuberculosis complex in individuals of all sites. Furthermore, we discuss the occurrence and spread of TB during the Neolithic with regard to nutritional aspects and possible risks of infection. The data presented provide important insights into the health status of Early Neolithic populations in Central Germany. PMID:23042554

  11. Changes of concave and convex rib-vertebral angle, angle difference and angle ratio in patients with right thoracic adolescent idiopathic scoliosis.

    PubMed

    Canavese, Federico; Turcot, Katia; Holveck, Jerôme; Farhoumand, Agnés Dahl; Kaelin, André

    2011-01-01

    The aim of this study is to describe the radiological changes in rib-vertebral angles (RVAs), rib-vertebral angle differences (RVADs), and rib-vertebral angle ratios (RVARas) in patients with untreated right thoracic adolescent idiopathic scoliosis and to compare with the normal subjects. The concave and convex RVA from T1 to T12, the RVADs and the RVARas were measured on AP digital radiographs of 44 female patients with right convex idiopathic scoliosis and 14 normal females. Patients were divided into three groups: normal subjects (group 1), scoliotic patients with Cobb's angle equal or <30° (group 2) and scoliotic patients with Cobb's angle over 30° (group 3). Overall values (mean ± SD) of the RVAs on the concave side were 90.5° ± 17° in group 1, 90.3° ± 15.8° in group 2 and 88.8° ± 15.4° in group 3. On the convex side, values were 90.0° ± 17.3° in group 1, 86.3° ± 13.7° in group 2 and 80.7° ± 14.4° in group 3. Overall values (mean ± SD) of the RVADs at all levels were 0.5° ± 0.7° in group 1, 4.0° ± 4.8° in group 2 and 8.0° ± 4.0° in group 3. The RVARa values (mean ± SD) at all levels was 1.008° ± 0.012° in group 1, 1.041° ± 0.061° in group 2 and 1.102° ± 0.151° in group 3. RVAD and RVARa values in the scoliotic segment were greater in patients with untreated scoliosis over 30° than in patients with an untreated deformity of <30° or normal subjects. A significant effect between groups was observed for the RVA, RVAD and RVARa variables. Measurement of RVA, RVAD and RVARa should not only be performed at and around the apex of a thoracic spinal deformity, but also extended to the whole thoracic spine. PMID:20811755

  12. Improved RF Isolation Amplifier

    NASA Technical Reports Server (NTRS)

    Stevens, G. L.; Macconnell, J.

    1985-01-01

    Circuit has high reverse isolation and wide bandwidth. Wideband isolation amplifier has low intermodulation distortion and high reverse isolation. Circuit does not require selected or matched components or directional coupling device. Circuit used in applications requiring high reverse isolation such as receiver intermediate-frequency (IF) strips and frequency distribution systems. Also applicable in RF and video signaling.

  13. Use of vortex generators and ribs for heat transfer enhancement at the top surface of a uniformly heated horizontal channel with mixed convection flow

    SciTech Connect

    Maughan, J.R.; Incropera, F.P. )

    1991-05-01

    Although secondary flows driven by buoyancy forces enhance heat transfer from the bottom surface of a heated, horizontal channel, heat transfer coefficients at the upper surface are known to remain near forced convection levels. In situations where performance is limited by the maximum local temperature, such as the cooling of electronic circuitry, enhanced heat transfer at one surface may be of little advantage if approximately equivalent enhancement does not exist at the opposite surface. Hence differences between top and bottom surface conditions may prevent a designer from taking full advantage of buoyancy-driven flows. This note reports on exploratory experiments to assess the feasibility of using mechanical vortex generators or perforated ribs at the top surface of a uniformly heated channel to provide comparable enhancement at both surfaces.

  14. Reconstruction with a pectoralis major myocutaneous flap after left first rib and clavicular chest wall resection for a metastasis from laryngeal cancer.

    PubMed

    Caronia, Francesco Paolo; Fiorelli, Alfonso; Zanchini, Fabio; Santini, Mario; Lo Monte, Attilio Ignazio; Castorina, Sergio

    2016-05-01

    We presented a case of recurrent metastasis from epidermoid cancer that occurred in the left clavicle of a patient with a history of laryngeal cancer treated on April 2005 with extended hemilaryngectomy, neck dissection and chemoradiation therapy. On September 2008, he developed a left clavicular metastasis. The disease was initially well controlled by chemoradiotherapy but it recurred 17 months later. The optimal treatment plan was established by several multidisciplinary meetings and the patient subsequently underwent an en bloc resection of the left clavicle, first rib and all the other involved structures. Coverage of the thoracic defect was achieved using pectoralis major myocutaneous flap. The patient had a successful surgical outcome. At 1-year follow-up, he had no evidence of disease, a good cosmetic result and returned to normal daily activity. He died for bone metastasis with an overall 21 months post-surgical survival. PMID:25319560

  15. Influence of gold nanoparticles on the 1.53 µm optical gain in Er3+/Yb3+: PbO-GeO2 RIB waveguides.

    PubMed

    da Silva, Davinson Mariano; Kassab, Luciana Reyes Pires; Siarkowski, Acácio L; de Araújo, Cid B

    2014-06-30

    We report the fabrication of waveguide amplifiers produced by RF-sputtering, using a PbO-GeO(2) glass (PGO glass) film codoped with Er(3+)/Yb(3+). RIB waveguides were obtained from PGO thin films using optical lithography followed by reactive ion etching process. The optical losses in the waveguide were ≈1.0 dB/cm and the maximum internal gain at 1.53 µm, with excitation at 980 nm, was 3 dB/cm. Nanostructured gold films deposited on the waveguides enhanced the Er(3+) ions photoluminescence (PL) by ≈400% in the red region and ≈30% in the infrared, under 980 nm pumping. The optical gain was enhanced and reached 6.5 dB/cm. The results demonstrate that the PGO waveguides, with or without gold nanoparticles, are promising for integrated photonics. PMID:24977891

  16. Optical modelling of a Si-based DBR laser source using a nanocrystal Si-sensitized Er-doped silica rib waveguide in the C-band

    NASA Astrophysics Data System (ADS)

    Ciminelli, C.; Frascella, P.; Armenise, M. N.

    2008-05-01

    The availability of reliable silicon-based laser sources is at the basis of the integration of photonic and microelectronic devices on a single chip with consequent development of wavelength division multiplexing telecommunication systems. A high efficiency Si-based laser source with good stability at room temperature would encourage and push the large scale of integration of electronic and photonic devices within a single chip. Several techniques have been proposed for generating light with an internal quantum efficiency some order of magnitude greater than that typical of silicon (10-6) by using either electrical or optical pumping. Among them we mention the improvement of some fabrication process steps, reduction of the channels of non-radiative recombination, quantum confinement, the use of silicon nanocrystals (Si-ncs) incorporated in a silica matrix. This last technique is used in combination with Er3+ doping to generate light emission around 1500 nm in silicon, since Er-doped Si-ncs behave as electron-hole pairs trap, and the presence of Er shifts the emission peak to around 1500 nm. In this paper we have pointed out the optical model of a Si-based DBR laser including a Si-ncs Er-doped SiO2 rib waveguide, working at a wavelength in C-band. In particular, after a brief description of the structural and optical properties of the silicon crystals, we report on the model and design of the Er:Si-nc/SiO2 rib waveguide, of the optical cavity and of the Bragg mirrors. Numerical results are in good agreement with the literature.

  17. CIP4 coordinates with phospholipids and actin-associated proteins to localize to the protruding edge and produce actin ribs and veils.

    PubMed

    Saengsawang, Witchuda; Taylor, Kendra L; Lumbard, Derek C; Mitok, Kelly; Price, Amanda; Pietila, Lauren; Gomez, Timothy M; Dent, Erik W

    2013-06-01

    Cdc42-interacting protein 4 (CIP4), a member of the F-BAR family of proteins, plays important roles in a variety of cellular events by regulating both membrane and actin dynamics. In many cell types, CIP4 functions in vesicle formation, endocytosis and membrane tubulation. However, recent data indicate that CIP4 is also involved in protrusion in some cell types, including cancer cells (lamellipodia and invadopodia) and neurons (ribbed lamellipodia and veils). In neurons, CIP4 localizes specifically to extending protrusions and functions to limit neurite outgrowth early in development. The mechanism by which CIP4 localizes to the protruding edge membrane and induces lamellipodial/veil protrusion and actin rib formation is not known. Here, we show that CIP4 localization to the protruding edge of neurons is dependent on both the phospholipid content of the plasma membrane and the underlying organization of actin filaments. Inhibiting phosphatidylinositol (3,4,5)-trisphosphate (PIP3) production decreases CIP4 at the membrane. CIP4 localization to the protruding edge is also dependent on Rac1/WAVE1, rather than Cdc42/N-WASP. Capping actin filaments with low concentrations of cytochalasin D or by overexpressing capping protein dramatically decreases CIP4 at the protruding edge, whereas inactivating Arp2/3 drives CIP4 to the protruding edge. We also demonstrate that CIP4 dynamically colocalizes with Ena/VASP and DAAM1, two proteins known to induce unbranched actin filament arrays and play important roles in neuronal development. Together, this is the first study to show that the localization of an F-BAR protein depends on both actin filament architecture and phospholipids at the protruding edge of developing neurons. PMID:23572514

  18. Viability of 3 D Woven Carbon Cloth and Advanced Carbon-Carbon Ribs for Adaptive Deployable Entry Placement Technology (ADEPT) for Future NASA Missions

    NASA Technical Reports Server (NTRS)

    Venkatapathy, Ethiraj; Arnold, James O.; Peterson, K. H.; Blosser, M. L.

    2013-01-01

    This paper describes aerothermodynamic and thermal structural testing that demonstrate the viability of three dimensional woven carbon cloth and advanced carbon-carbon (ACC) ribs for use in the Adaptive Deployable Entry Placement Technology (ADEPT). ADEPT is an umbrella-like entry system that is folded for stowage in the launch vehicle's shroud and deployed prior to reaching the atmeopheric interface. A key feature of the ADEPT concept is a lower ballistic coefficient for delivery of a given payload than seen with conventional, rigid body entry systems. The benefits that accrue from the lower ballistic coefficient incllude factor-of-ten reductions of deceleration forces and entry heating. The former enables consideration of new classes of scientific instruments for solar system exploration while the latter enables the design of a more efficient thermal protection system. The carbon cloth base lined for ADEPT has a dual use in that it serves as the thermal protection system and as the "skin" that transfers aerdynamic deceleration loads to its umbrella-like substructure. Arcjet testing described in this paper was conducted for some of the higher heating conditions for a future Venus mission using the ADEPT concept, thereby showing that the carbon cloth can perform in a relevant entry environment. Recently completed the thermal structural testing of the cloth attached to a representative ACC rib design is also described. Finally, this paper describes a preliminary engineering level code, based on the arcjet data, that can be used to estimate cloth thickness for future ADEPT missions and to predict carbon cloth performance in future arcjet tests.

  19. The fibroblast growth factor receptor, FGFR3, forms gradients of intact and degraded protein across the growth plate of developing bovine ribs.

    PubMed Central

    Pandit, Sujata G; Govindraj, Prasanthi; Sasse, Joachim; Neame, Peter J; Hassell, John R

    2002-01-01

    Point mutations in the human fibroblast growth factor (FGF) receptor 3 gene (Fgfr3) produce a constitutively active receptor, which disrupts chondrocyte differentiation in the growth plate and results in skeletal dysplasias with severe shortening of the limbs. Alternative splicing of the Fgfr3 transcript gives rise to two isoforms, IIIc and IIIb, which vary in their specificity for FGF ligands. We examined the expression of these FGFR3 isoforms in the bovine fetal rib growth plate to determine whether levels of FGFR3 expression are zone-related. Transcripts for both Fgfr3 isoforms are expressed in rib growth plate, with maximum expression in the hypertrophic region and the least expression in the reserve zone. Fgfr3 IIIc is the predominant isoform in the growth plate. Western-blot analysis revealed the presence of full-length FGFR3 (135 kDa) for both isoforms in the reserve zone, a major 98 kDa fragment in all zones and smaller fragments primarily in the hypertrophic zone. Immunostaining localized FGFR3 to the pericellular region of reserve chondrocytes and to the extracellular matrix in the hypertrophic zone. These results suggest that the transmembrane form of FGFR3 increasingly undergoes proteolytic cleavage towards the hypertrophic zone to produce an extracellular-domain fragment of FGFR3, which is present in large amounts in the matrix of hypertrophic cells. These findings suggest a proteolytic regulatory mechanism for FGFR3, whereby Fgfr3 fragments could control availability of FGF for the intact receptor, and by which proteolysis could inactivate the receptor. PMID:11772395

  20. CONSIDERATION OF DOSE LIMITS FOR ORGANS AT RISK OF THORACIC RADIOTHERAPY: ATLAS FOR LUNG, PROXIMAL BRONCHIAL TREE, ESOPHAGUS, SPINAL CORD, RIBS, AND BRACHIAL PLEXUS

    PubMed Central

    Kong, Feng-Ming (Spring); Ritter, Timothy; Quint, Douglas J.; Senan, Suresh; Gaspar, Laurie E.; Komaki, Ritsuko U.; Hurkmans, Coen W.; Timmerman, Robert; Bezjak, Andrea; Bradley, Jeffrey D.; Movsas, Benjamin; Marsh, Lon; Okunieff, Paul; Choy, Hak; Curran, Walter J.

    2012-01-01

    Purpose To review the dose limits and standardize the three-dimenional (3D) radiographic definition for the organs at risk (OARs) for thoracic radiotherapy (RT), including the lung, proximal bronchial tree, esophagus, spinal cord, ribs, and brachial plexus. Methods and Materials The present study was performed by representatives from the Radiation Therapy Oncology Group, European Organization for Research and Treatment of Cancer, and Soutwestern Oncology Group lung cancer committees. The dosimetric constraints of major multicenter trials of 3D-conformal RT and stereotactic body RT were reviewed and the challenges of 3D delineation of these OARs described. Using knowledge of the human anatomy and 3D radiographic correlation, draft atlases were generated by a radiation oncologist, medical physicist, dosimetrist, and radiologist from the United States and reviewed by a radiation oncologist and medical physicist from Europe. The atlases were then critically reviewed, discussed, and edited by another 10 radiation oncologists. Results Three-dimensional descriptions of the lung, proximal bronchial tree, esophagus, spinal cord, ribs, and brachial plexus are presented. Two computed tomography atlases were developed: one for the middle and lower thoracic OARs (except for the heart) and one focusing on the brachial plexus for a patient positioned supine with their arms up for thoracic RT. The dosimetric limits of the key OARs are discussed. Conclusions We believe these atlases will allow us to define OARs with less variation and generate dosimetric data in a more consistent manner. This could help us study the effect of radiation on these OARs and guide high-quality clinical trials and individualized practice in 3D-conformal RT and stereotactic body RT. PMID:20934273

  1. Consideration of Dose Limits for Organs at Risk of Thoracic Radiotherapy: Atlas for Lung, Proximal Bronchial Tree, Esophagus, Spinal Cord, Ribs, and Brachial Plexus

    SciTech Connect

    Kong, Feng-Ming; Ritter, Timothy; Quint, Douglas J.; Senan, Suresh; Gaspar, Laurie E.; Komaki, Ritsuko U.; Hurkmans, Coen W.; Timmerman, Robert; Bezjak, Andrea; Bradley, Jeffrey D.; Movsas, Benjamin; Marsh, Lon; Okunieff, Paul; Choy, Hak; Curran, Walter J.

    2011-12-01

    Purpose: To review the dose limits and standardize the three-dimenional (3D) radiographic definition for the organs at risk (OARs) for thoracic radiotherapy (RT), including the lung, proximal bronchial tree, esophagus, spinal cord, ribs, and brachial plexus. Methods and Materials: The present study was performed by representatives from the Radiation Therapy Oncology Group, European Organization for Research and Treatment of Cancer, and Soutwestern Oncology Group lung cancer committees. The dosimetric constraints of major multicenter trials of 3D-conformal RT and stereotactic body RT were reviewed and the challenges of 3D delineation of these OARs described. Using knowledge of the human anatomy and 3D radiographic correlation, draft atlases were generated by a radiation oncologist, medical physicist, dosimetrist, and radiologist from the United States and reviewed by a radiation oncologist and medical physicist from Europe. The atlases were then critically reviewed, discussed, and edited by another 10 radiation oncologists. Results: Three-dimensional descriptions of the lung, proximal bronchial tree, esophagus, spinal cord, ribs, and brachial plexus are presented. Two computed tomography atlases were developed: one for the middle and lower thoracic OARs (except for the heart) and one focusing on the brachial plexus for a patient positioned supine with their arms up for thoracic RT. The dosimetric limits of the key OARs are discussed. Conclusions: We believe these atlases will allow us to define OARs with less variation and generate dosimetric data in a more consistent manner. This could help us study the effect of radiation on these OARs and guide high-quality clinical trials and individualized practice in 3D-conformal RT and stereotactic body RT.

  2. Antigenic distribution of Streptococcus agalactiae isolates from pregnant women at Garankuwa hospital – South Africa

    PubMed Central

    Chukwu, Martina O; Mavenyengwa, Rooyen Tinago; Monyama, Charles M; Bolukaoto, John Y; Lebelo, Sogolo L; Maloba, Motlatji RB; Nchabeleng, Maphoshane; Moyo, Sylvester Rogers

    2015-01-01

    Introduction Streptococcus agalactiae (group B streptococcus; GBS) is globally recognised as one of the leading causes of neonatal sepsis and meningitis. It also causes adverse pregnancy outcomes such as stillbirth and miscarriages. Incidence of invasive disease is increasing in non-pregnant adults with underlying medical conditions (e.g., diabetes mellitus). Epidemiological studies of GBS infections are based on capsular serotyping. Genotyping of the surface anchored protein genes is also becoming an important tool for GBS studies. Currently ten different GBS serotypes have been identified. This study was performed to determine the prevalence of GBS capsular types (CTs) and surface anchored protein genes in isolates from colonized pregnant women attending antenatal clinic, at Dr George Mukhari Academic Hospital, Garankuwa, Pretoria, South Africa. Methods The samples were collected over 11 months and cultured on selective media. GBS was identified using different morphological and biochemical tests. Capsular typing was done using latex agglutination test and conventional PCR. Multiplex PCR with specific primers was used to detect the surface anchored protein genes. Results Of the 413 pregnant women recruited, 128 (30.9%) were colonized with GBS. The capsular polysaccharide (CPS) typing test showed that CPS type III (29.7%) was the most prevalent capsular type followed by CPS type Ia (25.8%), II (15.6%), IV (8.6%), V (10.9%) and Ib (8.6%); 0.7% of the isolates were nontypeable. Multiplex PCR revealed that the surface proteins genes were possessed by all the capsular types: rib (44.5%), bca (24.7%), alp2/3 (17.9%), epsilon (8.6%) and alp4 (4.7%). Conclusion The common capsular types found in this study are Ia, III, and II. The most common protein genes identified were rib and bca, and the distribution of the surface protein genes among the isolates of different capsular types showed similar trends to the distribution reported from previous studies. PMID:26716101

  3. Psychopathology of social isolation

    PubMed Central

    Baek, Sang-Bin

    2014-01-01

    The most important defining factor of being human is the use of symbolic language. Language or communication problem occurs during the growth, the child will have a higher risk of social isolation and then the survival will be threatened constantly. Today, adolescents and youths are familiar with computer and smart-phone devices, and communication with others by these devices is easy than face-to-face communication. As adolescents and youths live in the comfortable and familiar cyber-world rather than actively participating real society, so they make social isolation. Extreme form of this isolation in adolescents and youths is so-called Socially Withdrawn Youth. In this study, the psychopathological factors inducing social isolation were discussed. Development stages of social isolation in relation with types of social isolation, Ego-syntonic isolation and Ego-dystonic isolation, were also considered. PMID:25061592

  4. Comparison of the Efficacy of Everolimus-Eluting Stents Versus Drug-Eluting Balloons in Patients With In-Stent Restenosis (from the RIBS IV and V Randomized Clinical Trials).

    PubMed

    Alfonso, Fernando; Pérez-Vizcayno, María José; García Del Blanco, Bruno; García-Touchard, Arturo; Masotti, Mónica; López-Minguez, José R; Iñiguez, Andrés; Zueco, Javier; Velazquez, Maite; Cequier, Angel; Lázaro-García, Rosa; Martí, Vicens; Moris, César; Urbano-Carrillo, Cristobal; Bastante, Teresa; Rivero, Fernando; Cárdenas, Alberto; Gonzalo, Nieves; Jiménez-Quevedo, Pilar; Fernández, Cristina

    2016-02-15

    Treatment of patients with in-stent restenosis (ISR) remains a challenge. This study sought to compare the efficacy of everolimus-eluting stents (EESs) and drug-eluting balloons (DEBs) with paclitaxel in patients with ISR. A pooled analysis of the Restenosis Intra-Stent of Drug-Eluting Stents: Drug-Eluting Balloon vs Everolimus-Eluting Stent (RIBS IV) and Restenosis Intra-Stent of Bare-Metal Stents: Drug-Eluting Balloon vs Everolimus-Eluting Stent (RIBS V) randomized trials was performed using patient-level data. In both trials, EESs were compared with DEBs in patients with ISR (RIBS V included 189 patients with bare-metal ISR; RIBS IV included 309 patients with drug-eluting ISR). Inclusion and exclusion criteria were identical in both trials. A total of 249 patients were allocated to EES and 249 to DEB. Clinical follow-up at 1 year was obtained in all (100%) patients and late angiography (median 249 days) in 91% of eligible patients. Compared with patients treated with DEBs, patients treated with EESs obtained better short-term results (postprocedural minimal lumen diameter 2.28 ± 0.5 vs 2.12 ± 0.4 mm, p <0.0001). At follow-up, patients treated with EESs had larger in-segment minimal lumen diameter (primary end point 2.16 ± 0.7 vs 1.88 ± 0.6 mm, p <0.0001; absolute mean difference 0.28 mm; 95% confidence interval [CI] 0.16 to 0.40) and net lumen gain (1.33 ± 0.6 vs 1.00 ± 0.7 mm, p <0.0001) and had lower %diameter stenosis (19 ± 21% vs 28 ± 22%, p <0.0001) and binary restenosis rate (8.7% vs 15.7%, p = 0.02). Consistent results were observed in the in-lesion analysis. No interactions were found between the underlying stent type and treatment effects. At 1-year clinical follow-up, the composite of cardiac death, myocardial infarction, and target vessel revascularization was significantly reduced in the EES arm (8.8% vs 14.5%, p = 0.03; hazard ratio 0.59, 95% CI 0.31 to 0.94) mainly driven by a lower need for target vessel revascularization (6% vs 12.4%, p

  5. On line Release Simulator of Radioactive Beams produced by ISOL technique

    SciTech Connect

    Turrion, Manuela; Tengblad, Olof; Borge, Maria J. G.; Reillo, Eva; Morrissey, Edward R.; Santana, Mario

    2007-02-12

    Target and ion source constitute the heart for the production of radioactive ion beams, RIBs. The goal of this work is to help in the development of reliable and efficient target and ion source systems for production of short-lived isotopes of a wide range of elements by the ISOL method. With this aim an oracle database of diffusion and desorption parameters with more than 10.000 entries has been built. The database is accessible on line and a web application has been developed allowing the retrieval of information from the database in order to assist in the configuration of the input parameters for a Monte Carlo code, RIBO, for the simulation of target-ion source systems.

  6. CFD analysis and optimization of a liquid lead-bismuth loop target for ISOL facilities

    NASA Astrophysics Data System (ADS)

    Houngbo, D.; Popescu, L.; Schuurmans, P.; Delonca, M.; Losito, R.; Maglioni, C.; Stora, T.; Bricault, P.; Vierendeels, J.

    2015-03-01

    In the context of the forthcoming next generation of Radioactive Ion Beams (RIBs) facilities based on an Isotope Separation On Line (ISOL) method, the development of production targets capable of dissipating the high power deposited by the primary beam is a major challenge. The concept of a high-power target based on a liquid Pb-Bi loop incorporating a heat-exchanger and a diffusion chamber was proposed within EURISOL DS and is being developed within the LIEBE1 This study shows that approximately 100 ms after the proton pulse the irradiated liquid-metal is entirely and uniformly evacuated from the irradiation volume and spread in a shower of small droplets (100-μm radii), in order to reduce the diffusion length of isotopes. Solutions to deal with the typical cavitation risk due to the presence of low-pressure zones in the liquid have also been found and simulated.

  7. [Isolated chest trauma in elderly patients].

    PubMed

    Yersin, Bertrand; Carron, Pierre-Nicolas; Pasquier, Mathieu; Zingg, Tobias

    2015-08-12

    In elderly patients, a blunt trauma of the chest is associated with a significant risk of complications and mortality. The number of ribs fractures (≥ 4), the presence of bilateral rib fractures, of a pulmonary contusion, of existent comorbidities or acute extra-thoracic traumatic lesions, and lastly the severity of thoracic pain, are indeed important risk factors of complications and mortality. Their presence may require hospitalization of the patient. When complications do occur, they are represented by alveolar hypoventilation, pulmonary atelectasia and broncho-pulmonary infections. When hospitalization is required, it may allow for the specific treatment of thoracic pain, including locoregional anesthesia techniques. PMID:26449103

  8. Isolation and phylogenetic analysis of Bartonella species from wild carnivores of the suborder Caniformia in Japan.

    PubMed

    Sato, Shingo; Kabeya, Hidenori; Miura, Tatsuya; Suzuki, Kazuo; Bai, Ying; Kosoy, Michael; Sentsui, Hiroshi; Kariwa, Hiroaki; Maruyama, Soichi

    2012-12-28

    The prevalence of Bartonella species was investigated among wild carnivores of the suborder Caniformia, including 15 Japanese badgers (Meles anakuma), 8 Japanese martens (Martes melampus), 2 Japanese weasels (Mustela itatsi), 1 Siberian weasel (Mustela sibirica), 171 raccoon dogs (Nyctereutes procyonoides), and 977 raccoons (Procyon lotor) in Japan. Bartonella bacteria were isolated from one Japanese badger (6.7%) and from one Japanese marten (12.5%); however, no Bartonella species was found in other representatives of Caniformia. Phylogenetic analysis was based on concatenated sequences of six housekeeping genes (16S rRNA, ftsZ, gltA, groEL, ribC, and rpoB) and sequence of the 16S-23S internal transcribed spacer region. The sequence analysis indicated that the isolate derived from the Japanese badger (strain JB-15) can represent a novel Bartonella species and the isolate from the Japanese marten (strain JM-1) was closely related to Bartonella washoensis. This is the first report on isolation of Bartonella from badger and marten. PMID:22841404

  9. Nutrient database improvement project: the influence of U.S.D.A. Quality and Yield Grade on the separable components and proximate composition of raw and cooked retail cuts from the beef rib and plate.

    PubMed

    Martin, J N; Brooks, J C; Thompson, L D; Savell, J W; Harris, K B; May, L L; Haneklaus, A N; Schutz, J L; Belk, K E; Engle, T; Woerner, D R; Legako, J F; Luna, A M; Douglass, L W; Douglass, S E; Howe, J; Duvall, M; Patterson, K Y; Leheska, J L

    2013-11-01

    Beef nutrition is important to the worldwide beef industry. The objective of this study was to analyze proximate composition of eight beef rib and plate cuts to update the USDA National Nutrient Database for Standard Reference (SR). Furthermore, this study aimed to determine the influence of USDA Quality Grade on the separable components and proximate composition of the examined retail cuts. Carcasses (n=72) representing a composite of Yield Grade, Quality Grade, gender and genetic type were identified from six regions across the U.S. Beef plates and ribs (IMPS #109 and 121C and D) were collected from the selected carcasses and shipped to three university meat laboratories for storage, retail fabrication, cooking, and dissection and analysis of proximate composition. These data provide updated information regarding the nutrient content of beef and emphasize the influence of common classification systems (Yield Grade and Quality Grade) on the separable components, cooking yield, and proximate composition of retail beef cuts. PMID:23793084

  10. Identification of novel DYNC2H1 mutations associated with short rib-polydactyly syndrome type III using next-generation panel sequencing.

    PubMed

    Chen, L S; Shi, S J; Zou, P S; Ma, M; Chen, X H; Cao, D H

    2016-01-01

    Short rib-polydactyly syndrome type III (SRPS3) is a perinatal lethal skeletal disorder with polydactyly and multisystem organ abnormalities. While ultrasound of the fetus can detect skeletal abnormalities characteristic of SRPS3, the syndrome is often difficult to diagnose before birth. As SRPS3 is an autosomal recessive disorder, identification of the gene mutations involved could lead to the development of prenatal genetic testing as an accurate method of diagnosis. In this study, we describe genetic screening approaches to identify potential abnormalities associated with SRPS3. Karyotype analysis, array comparative genomic hybridization (aCGH), and next-generation panel sequencing were each performed on a fetus showing signs of the disorder, as well as on the mother and father. Karyotype and aCGH results revealed no abnormalities. However, next-generation panel sequencing identified novel mutations in the DYNC2H1 gene. The fetus was compound heterozygous for both a missense mutation c.8313A > T and a frameshift mutation c.10711_10714delTTTA in the DYNC2H1 gene, which were inherited from the mother and father, respectively. These variants were further confirmed using Sanger sequencing and have not been previously reported. Our study indicates the utility of using next-generation panel sequencing in screening for novel disease-associated mutations. PMID:27323140

  11. Systematic review of diplommatinid land snails (Caenogastropoda, Diplommatinidae) endemic to the Palau Islands. (2) Taxonomic revision of Hungerfordia species with low axial ribs.

    PubMed

    Yamazaki, Kazunori; Yamazaki, Midori; Ueshima, Rei

    2015-01-01

    Hungerfordia Beddome, 1889 is a terrestrial caenogastropod genus of the family Diplommatinidae endemic to the Palau (Belau) islands. Hungerfordia is radiated within the Palau islands and exhibits substantial morphological diversity. In this paper, the taxonomy of Hungerfordia species with low axial ribs is revised. Hungerfordia polymorpha (Crosse, 1866), H. inflatula (Crosse, 1866), H. crassilabris crassilabris (Beddome, 1889), H. lutea lutea (Beddome, 1889), H. ringens ringens (Crosse, 1866), H. pyramis pyramis (Crosse, 1866), and H. aurea (Beddome, 1889) are redescribed based on the syntypes and newly collected materials. The following new taxa are described: H. aspera sp. nov., H. basodonta sp. nov., H. microbasodonta sp. nov., H. rudicostata sp. nov., H. unisulcata sp. nov., H. longissima sp. nov., H. eurystoma sp. nov., H. crenata sp. nov., H. crassilabris tridentata subsp. nov., H. crassilabris attenuata subsp. nov., H. lutea hemilaevis subsp. nov., H. loxodonta sp. nov., H. omphaloptyx sp. nov., H. robiginosa sp. nov., H. angaurensis sp. nov., H. ringens rotundata subsp. nov., H. ringens ventrinodus subsp. nov., H. pyramis pteroma subsp. nov., H. spinoscapula sp. nov. PMID:26249932

  12. Mutation and premating isolation

    NASA Technical Reports Server (NTRS)

    Woodruff, R. C.; Thompson, J. N. Jr

    2002-01-01

    While premating isolation might be traceable to different genetic mechanisms in different species, evidence supports the idea that as few as one or two genes may often be sufficient to initiate isolation. Thus, new mutation can theoretically play a key role in the process. But it has long been thought that a new isolation mutation would fail, because there would be no other individuals for the isolation-mutation-carrier to mate with. We now realize that premeiotic mutations are very common and will yield a cluster of progeny carrying the same new mutant allele. In this paper, we discuss the evidence for genetically simple premating isolation barriers and the role that clusters of an isolation mutation may play in initiating allopatric, and even sympatric, species divisions.

  13. Module isolation devices

    SciTech Connect

    Carolan, Michael Francis; Cooke, John Albert; Buzinski, Michael David

    2010-04-27

    A gas flow isolation device includes a gas flow isolation valve movable from an opened condition to a closed condition. The module isolation valve in one embodiment includes a rupture disk in flow communication with a flow of gas when the module isolation valve is in an opened condition. The rupture disk ruptures when a predetermined pressure differential occurs across it causing the isolation valve to close. In one embodiment the valve is mechanically linked to the rupture disk to maintain the valve in an opened condition when the rupture disk is intact, and which permits the valve to move into a closed condition when the rupture disk ruptures. In another embodiment a crushable member maintains the valve in an open condition, and the flow of gas passed the valve upon rupturing of the rupture disk compresses the crushable member to close the isolation valve.

  14. Positive isolation disconnect

    NASA Technical Reports Server (NTRS)

    Rosener, A. A.; Jonkoniec, T. G.

    1975-01-01

    A positive isolation disconnect was developed for component replacement in serviced liquid and gaseous spacecraft systems. Initially a survey of feasible concepts was made to determine the optimum method for fluid isolation, sealing techniques, coupling concepts, and foolproofing techniques. The top concepts were then further evaluated, including the fabrication of a semifunctional model. After all tradeoff analyses were made, a final configuration was designed and fabricated for development testing. This resulted in a 6.35 mm (1/4 inch) line and 12.7 mm (1/2 inch) line positive isolation disconnect, each unit consisting of two coupled disconnect halves, each capable of fluid isolation with essentially zero clearance between them for zero leakage upon disconnect half disengagement. An interlocking foolproofing technique was incorporated that prevents uncoupling of disconnect halves prior to fluid isolation.

  15. Development of plasmonic isolator for integration into photonic integrated circuits (Presentation Recording)

    NASA Astrophysics Data System (ADS)

    Zayets, Vadym; Saito, Hidekazu; Ando, Koji; Yuasa, Shinji

    2015-09-01

    An optical isolator is an important component of an optical network. At present, there is a significant commercial demand for an optical isolator, which can be integrated into the Photonic Integrated Circuits (PIC). A new design of an integrated optical isolator, which utilizes unique non-reciprocal properties of surface plasmons, has been proposed [1]. The main obstacle for a practical realization of the proposed design is a substantial propagation loss of the surface plasmons in structures containing a ferromagnetic metal. The reduction of the propagation loss of a surface plasmon is the key to make the plasmonic isolator competitive with other designs of the integrated isolator. We studied experimentally optical and magneto-optical properties of a Fe plasmonic waveguide integrated with an AlGaAs rib waveguides and a Co plasmonic waveguide integrated with Si nanowire waveguides. It was demonstrated experimentally that by utilizing a double-dielectric plasmonic waveguide it is possible to reduce significantly the optical loss in a plasmonic waveguide. For Fe/SiO2/AlGaAs double-dielectric plasmonic waveguide the low optical loss of 0.03 dB/um is obtained. As far as we know at present it is a lowest optical loss demonstrated for a plasmon propagating at a surface of a ferromagnetic metal. For Co/Ti2O3/SiO2 double-dielectric plasmonic waveguide integrated with a Si nanowire waveguide on a Si substrate the optical loss of 0.7 dB/um was demonstrated. The designs of the plasmonic isolator utilizing a ring resonator or a non-reciprocal coupler were studied. [1] V. Zayets, H. Saito, S. Yuasa, and K. Ando,, Materials 5, 857 (2012).

  16. Serovar 4b complex predominates among Listeria monocytogenes isolates from imported aquatic products in China.

    PubMed

    Chen, Jianshun; Chen, Qiaomiao; Jiang, Jianjun; Hu, Hongxia; Ye, Jiangbo; Fang, Weihuan

    2010-01-01

    Listeria monocytogenes, the causative organism of listeriosis, is primarily transmitted to humans through contaminated food. In this study, we examined 1275 batches of aquatic products imported from 29 countries and found that 36 batches from 8 countries were contaminated by Listeria (2.8%), with L. monocytogenes accounting for 2.6% (33/1275) and L. innocua for 0.2% (3/1275). Of the 23 selected L. monocytogenes isolates (from the 33 identified), 15 (65.2%) were of serovar 4b complex (4b, 4d, or 4e), three (13.0%) of 1/2a or 3a, four (17.4%) of 1/2b or 3b, and one (4.4%) of 1/2c or 3c. Notably, four of the 23 isolates belonged to epidemic clone I (ECI) and another four were associated with epidemic clone II (ECII), two highly clonal 4b clusters responsible for most of the documented listeriosis outbreaks. In the multilocus sequence typing scheme based on the concatenated genes gyrB-dapE-hisJ-sigB-ribC-purM-betL-gap-tuf, serovar 4b complex isolates from imported aquatic products exhibited significant genetic diversity. While the four ECI isolates were genetically related to those from Chinese diseased animals, both lacking one proline-rich repeat of ActA, the four ECII isolates were located between 1/2b or 3b strains. As the L. monocytogenes isolates from imported aquatic products possessed a nearly complete set of major infection-related genes, they demonstrated virulence potential in mouse model. PMID:19735205

  17. Characterization and antibiotic susceptibility of Streptococcus agalactiae isolates causing urinary tract infections.

    PubMed

    Piccinelli, Giorgio; Biscaro, Valeria; Gargiulo, Franco; Caruso, Arnaldo; De Francesco, Maria Antonia

    2015-08-01

    Streptococcus agalactiae (GBS) has been implicated in urinary tract infections but the microbiological characteristics and antimicrobial susceptibility of these strains are poorly investigated. In this study, 87 isolates recovered from urine samples of patients who had attended the Spedali Civili of Brescia (Italy) and had single organism GBS cultured were submitted to antimicrobial susceptibility testing, molecular characterization of macrolide and levofloxacin resistance, PCR-based capsular typing and analysis of surface protein genes. By automated broth microdilution method, all isolates were susceptible to penicillin, cefuroxime, cefaclor, and ceftriaxone; 80%, 19.5% and 3.4% of isolates were non-susceptible to tetracycline, erythromycin, and levofloxacin, respectively. Macrolide resistance determinants were iMLS(B) (n=1), cMLS(B) (n=10) and M (n=5), associated with ermTR, ermB and mefA/E. Levofloxacin resistance was linked to mutations in gyrA and parC genes. Predominant capsular types were III, Ia, V, Ib and IX. Type III was associated with tetracycline resistance, while type Ib was associated with levofloxacin resistance. Different capsular type-surface protein gene combinations (serotype V-alp2, 3; serotype III-rib; serotype Ia-epsilon) were detected. A variety of capsular types are involved in significant bacteriuria. The emergence of multidrug resistant GBS may become a significant public health concern and highlights the importance of careful surveillance to prevent the emergence of these virulent GBS. PMID:26144658

  18. Fine De Novo Sequencing of a Fungal Genome Using only SOLiD Short Read Data: Verification on Aspergillus oryzae RIB40

    PubMed Central

    Takeda, Itaru; Hagiwara, Hiroko; Ikegami, Tsutomu; Koike, Hideaki; Machida, Masayuki

    2013-01-01

    The development of next-generation sequencing (NGS) technologies has dramatically increased the throughput, speed, and efficiency of genome sequencing. The short read data generated from NGS platforms, such as SOLiD and Illumina, are quite useful for mapping analysis. However, the SOLiD read data with lengths of <60 bp have been considered to be too short for de novo genome sequencing. Here, to investigate whether de novo sequencing of fungal genomes is possible using only SOLiD short read sequence data, we performed de novo assembly of the Aspergillus oryzae RIB40 genome using only SOLiD read data of 50 bp generated from mate-paired libraries with 2.8- or 1.9-kb insert sizes. The assembled scaffolds showed an N50 value of 1.6 Mb, a 22-fold increase than those obtained using only SOLiD short read in other published reports. In addition, almost 99% of the reference genome was accurately aligned by the assembled scaffold fragments in long lengths. The sequences of secondary metabolite biosynthetic genes and clusters, whose products are of considerable interest in fungal studies due to their potential medicinal, agricultural, and cosmetic properties, were also highly reconstructed in the assembled scaffolds. Based on these findings, we concluded that de novo genome sequencing using only SOLiD short reads is feasible and practical for molecular biological study of fungi. We also investigated the effect of filtering low quality data, library insert size, and k-mer size on the assembly performance, and recommend for the assembly use of mild filtered read data where the N50 was not so degraded and the library has an insert size of ∼2.0 kb, and k-mer size 33. PMID:23667655

  19. Downflow dryout in a heated ribbed vertical annulus with a cosine power profile (Results from test series ECS-2, WSR, and ECS-2cE)

    SciTech Connect

    Larson, T.K.; Anderson, J.L.; Condie, K.G.

    1990-12-01

    Experiments designed to investigate surface dryout in a heated, ribbed annulus test section simulating one of the annular coolant channels of a Savannah River Plant production reactor Mark 22 fuel assembly have been conducted at the Idaho National Engineering Laboratory. The inner surface of the annulus was constructed of aluminum and was electrically heated to provide an axial cosine power profile and a flat azimuthal power shape. Data presented in this report are from the ECS-2, WSR, and ECS-2cE series of tests. These experiments were conducted to examine the onset of wall thermal excursion for a range of flow, inlet fluid temperature, and annulus outlet pressure. Hydraulic boundary conditions on the test section represent flowrates (0.1--1.4 1/s), inlet fluid temperatures (293--345 K), and outlet pressures (-18--139.7 cm of water relative to the bottom of the heated length (61--200 cm of water relative to the bottom of the lower plenum)) expected to occur during the Emergency Coolant System (ECS) phase of postulated Loss-of-Coolant Accident in a production reactor. The onset of thermal excursion based on the present data is consistent with data gathered in test rigs with flat axial power profiles. The data indicate that wall dryout is primarily a function of liquid superficial velocity. Air entrainment rate was observed to be a strong function of the boundary conditions (primarily flowrate and liquid temperature), but had a minor effect on the power at the onset of thermal excursion for the range of conditions examined. 14 refs., 33 figs., 13 tabs.

  20. Using a physically-based model, tRIBS-Erosion, for investigating the effects of climate change in semi-arid headwater basins.

    NASA Astrophysics Data System (ADS)

    Francipane, Antonio; Fatichi, Simone; Ivanov, Valeriy Y.; Noto, Leonardo V.

    2013-04-01

    Soil erosion due to rainfall detachment and flow entrainment of soil particles is a physical process responsible for a continuous evolution of landscapes. The rate and spatial distribution of this phenomenon depend on several factors such as climate, hydrologic regime, geomorphic characteristics, and vegetation of a basin. Many studies have demonstrated that climate-erosion linkage in particular influences basin sediment yield and landscape morphology. Although soil erosion rates are expected to change in response to climate, these changes can be highly non-linear and thus require mechanistic understanding of underlying causes. In this study, an integrated geomorphic component of the physically-based, spatially distributed hydrological model, tRIBS, the TIN-based Real-time Integrated Basin Simulator, is used to analyze the sensitivity of semi-arid headwater basins to climate change. Downscaled outputs of global circulation models are used to inform a stochastic weather generator that produces an ensemble of climate scenarios for an area in the Southwest U.S. The ensemble is used as input to the integrated model that is applied to different headwater basins of the Walnut Gulch Experimental Watershed to understand basin response to climate change in terms of runoff and sediment yield. Through a model application to multiple catchments, a scaling relationship between specific sediment yield and drainage basin area is also addressed and probabilistic inferences on future changes in catchment runoff and yield are drawn. Geomorphological differences among catchments do not influence specific changes in runoff and sediment transport that are mostly determined by precipitation changes. Despite a large uncertainty dictated by climate change projections and stochastic variability, sediment transport is predicted to decrease despite a non-negligible possibility of larger runoff rates.

  1. Fault detection and isolation

    NASA Technical Reports Server (NTRS)

    Bernath, Greg

    1994-01-01

    In order for a current satellite-based navigation system (such as the Global Positioning System, GPS) to meet integrity requirements, there must be a way of detecting erroneous measurements, without help from outside the system. This process is called Fault Detection and Isolation (FDI). Fault detection requires at least one redundant measurement, and can be done with a parity space algorithm. The best way around the fault isolation problem is not necessarily isolating the bad measurement, but finding a new combination of measurements which excludes it.

  2. Isolated sleep paralysis

    MedlinePlus

    ... from sleep. It is not associated with another sleep disorder. Symptoms Episodes of isolated sleep paralysis last from ... A.M. Editorial team. Related MedlinePlus Health Topics Sleep Disorders Browse the Encyclopedia A.D.A.M., Inc. ...

  3. Base isolation: Fresh insight

    SciTech Connect

    Shustov, V.

    1993-07-15

    The objective of the research is a further development of the engineering concept of seismic isolation. Neglecting the transient stage of seismic loading results in a widespread misjudgement: The force of resistance associated with velocity is mostly conceived as a source of damping vibrations, though it is an active force at the same time, during an earthquake type excitation. For very pliant systems such as base isolated structures with relatively low bearing stiffness and with artificially added heavy damping mechanism, the so called `damping`` force may occur even the main pushing force at an earthquake. Thus, one of the two basic pillars of the common seismic isolation philosophy, namely, the doctrine of usefulness and necessity of a strong damping mechanism, is turning out to be a self-deception, sometimes even jeopardizing the safety of structures and discrediting the very idea of seismic isolation. There is a way out: breaking with damping dependancy.

  4. Isolated sleep paralysis.

    PubMed

    Sawant, Neena S; Parkar, Shubhangi R; Tambe, Ravindra

    2005-10-01

    Sleep paralysis (SP) is a cardinal symptom of narcolepsy. However, little is available in the literature about isolated sleep paralysis. This report discusses the case of a patient with isolated sleep paralysis who progressed from mild to severe SP over 8 years. He also restarted drinking alcohol to be able to fall asleep and allay his anxiety symptoms. The patient was taught relaxation techniques and he showed complete remission of the symptoms of SP on follow up after 8 months. PMID:20711316

  5. Launch vehicle payload adapter design with vibration isolation features

    NASA Astrophysics Data System (ADS)

    Thomas, Gareth R.; Fadick, Cynthia M.; Fram, Bryan J.

    2005-05-01

    Payloads, such as satellites or spacecraft, which are mounted on launch vehicles, are subject to severe vibrations during flight. These vibrations are induced by multiple sources that occur between liftoff and the instant of final separation from the launch vehicle. A direct result of the severe vibrations is that fatigue damage and failure can be incurred by sensitive payload components. For this reason a payload adapter has been designed with special emphasis on its vibration isolation characteristics. The design consists of an annular plate that has top and bottom face sheets separated by radial ribs and close-out rings. These components are manufactured from graphite epoxy composites to ensure a high stiffness to weight ratio. The design is tuned to keep the frequency of the axial mode of vibration of the payload on the flexibility of the adapter to a low value. This is the main strategy adopted for isolating the payload from damaging vibrations in the intermediate to higher frequency range (45Hz-200Hz). A design challenge for this type of adapter is to keep the pitch frequency of the payload above a critical value in order to avoid dynamic interactions with the launch vehicle control system. This high frequency requirement conflicts with the low axial mode frequency requirement and this problem is overcome by innovative tuning of the directional stiffnesses of the composite parts. A second design strategy that is utilized to achieve good isolation characteristics is the use of constrained layer damping. This feature is particularly effective at keeping the responses to a minimum for one of the most important dynamic loading mechanisms. This mechanism consists of the almost-tonal vibratory load associated with the resonant burn condition present in any stage powered by a solid rocket motor. The frequency of such a load typically falls in the 45-75Hz range and this phenomenon drives the low frequency design of the adapter. Detailed finite element analysis is

  6. Systematic review of diplommatinid land snails (Caenogastropoda, Diplommatinidae) endemic to the Palau Islands. (1) Generic classification and revision of Hungerfordia species with highly developed axial ribs.

    PubMed

    Yamazaki, Kazunori; Yamazaki, Midori; Ueshima, Rei

    2013-01-01

    Diplommatinidae is a family of terrestrial caenogastropod snails that shows extensive species diversity and endemic radiation within the Palau (Belau) Islands. In this paper, we revised the taxonomy of Palauan endemic diplommatinids based on the comparative morphology of shell, operculum, radula, and genitalia. Although the generic classification of Palauan diplommatinids has been confusing, they are currently classified into two genera, Hungerfordia Beddome, 1889 and Palaina Semper, 1865. Palauan diplommatinids of these two genera are primarily distinguished by the radular, genital and operculum morphology. However, shell morphology, on which taxonomy has traditionally been based, does not provide definitive characters for generic identification, because shell shape and sculpture are highly variable within each genus. Although Hungerfordia has long been known as a monotypic genus, the current study redefines the endemic genus to include a wider range of species that were formerly placed in Diplommatina or Palaina. Following species are transferred to Hungerfordia: H. alata (Crosse, 1866) comb. nov.; H. lamellata (Crosse, 1866) comb. nov.; H. pyramis (Crosse, 1866) comb. nov.; H. ringens (Crosse, 1866) comb. nov.; H. polymorpha (Crosse, 1866) comb. nov.; H. inflatula (Crosse, 1866) comb. nov.; H. lutea (Beddome, 1889) comb. nov.; H. aurea (Beddome, 1889) comb. nov.; H. gibboni (Beddome, 1889) comb. nov.; H. crassilabris (Beddome, 1889) comb. nov. Pseudopalaina Moellendorff in Kobelt & Moellendorff, 1898 (synonym nov.) is demoted as a junior synonym of Hungerfordia. Palaina is also redefined based on the internal shell features and operculum morphology, in addition to the external shell characters. Furthermore, Eupalaina Kobelt & Moellendorff, 1898 is restored as a subgenus of Palaina for Palauan species on the basis of a genital character. The taxonomy of Hungerfordia species with highly developed axial ribs is revised. H. pelewensis Beddome, 1889, H. lamellata

  7. A mechanical chest compressor closed-loop controller with an effective trade-off between blood flow improvement and ribs fracture reduction.

    PubMed

    Zhang, Guang; Wu, Taihu; Song, Zhenxing; Wang, Haitao; Lu, Hengzhi; Wang, Yalin; Wang, Dan; Chen, Feng

    2015-06-01

    Chest compression (CC) is a significant emergency medical procedure for maintaining circulation during cardiac arrest. Although CC produces the necessary blood flow for patients with heart arrest, improperly deep CC will contribute significantly to the risk of chest injury. In this paper, an optimal CC closed-loop controller for a mechanical chest compressor (OCC-MCC) was developed to provide an effective trade-off between the benefit of improved blood perfusion and the risk of ribs fracture. The trade-off performance of the OCC-MCC during real automatic mechanical CCs was evaluated by comparing the OCC-MCC and the traditional mechanical CC method (TMCM) with a human circulation hardware model based on hardware simulations. A benefit factor (BF), risk factor (RF) and benefit versus risk index (BRI) were introduced in this paper for the comprehensive evaluation of risk and benefit. The OCC-MCC was developed using the LabVIEW control platform and the mechanical chest compressor (MCC) controller. PID control is also employed by MCC for effective compression depth regulation. In addition, the physiological parameters model for MCC was built based on a digital signal processor for hardware simulations. A comparison between the OCC-MCC and TMCM was then performed based on the simulation test platform which is composed of the MCC, LabVIEW control platform, physiological parameters model for MCC and the manikin. Compared with the TMCM, the OCC-MCC obtained a better trade-off and a higher BRI in seven out of a total of nine cases. With a higher mean value of cardiac output (1.35 L/min) and partial pressure of end-tidal CO2 (15.7 mmHg), the OCC-MCC obtained a larger blood flow and higher BF than TMCM (5.19 vs. 3.41) in six out of a total of nine cases. Although it is relatively difficult to maintain a stable CC depth when the chest is stiff, the OCC-MCC is still superior to the TMCM for performing safe and effective CC during CPR. The OCC-MCC is superior to the TMCM in

  8. Clinical Islet Isolation.

    PubMed

    Hawthorne, Wayne J; Williams, Lindy; Chew, Yi Vee

    2016-01-01

    The overarching success of islet transplantation relies on the success in the laboratory to isolate the islets. This chapter focuses on the processes of human islet cell isolation and the ways to optimally provide islet cells for transplantation. The major improvements in regards to the choice of enzyme type, way the digested pancreas tissue is handled to best separate islets from the acinar and surrounding tissues, the various methods of purification of the islets, their subsequent culture and quality assurance to improve outcomes to culminate in safe and effective islet transplantation will be discussed. After decades of improvements, islet cell isolation and transplantation now clearly offer a safe, effective and feasible therapeutic treatment option for an increasing number of patients suffering from type 1 diabetes specifically for those with severe hypoglycaemic unawareness. PMID:27586424

  9. Strain isolated ceramic coatings

    NASA Technical Reports Server (NTRS)

    Tolokan, R. P.; Brady, J. B.; Jarrabet, G. P.

    1985-01-01

    Plasma sprayed ceramic coatings are used in gas turbine engines to improve component temperature capability and cooling air efficiency. A compliant metal fiber strain isolator between a plasma sprayed ceramic coating and a metal substrate improves ceramic durability while allowing thicker coatings for better insulation. Development of strain isolated coatings has concentrated on design and fabrication of coatings and coating evaluation via thermal shock testing. In thermal shock testing, five types of failure are possible: buckling failure im compression on heat up, bimetal type failure, isothermal expansion mismatch failure, mudflat cracking during cool down, and long term fatigue. A primary failure mode for thermally cycled coatings is designated bimetal type failure. Bimetal failure is tensile failure in the ceramic near the ceramic-metal interface. One of the significant benefits of the strain isolator is an insulating layer protecting the metal substrate from heat deformation and thereby preventing bimetal type failure.

  10. Nucleic acid isolation

    DOEpatents

    Longmire, J.L.; Lewis, A.K.; Hildebrand, C.E.

    1988-01-21

    A method is provided for isolating DNA from eukaryotic cell and flow sorted chromosomes. When DNA is removed from chromosome and cell structure, detergent and proteolytic digestion products remain with the DNA. These products can be removed with organic extraction, but the process steps associated with organic extraction reduces the size of DNA fragments available for experimental use. The present process removes the waste products by dialyzing a solution containing the DNA against a solution containing polyethylene glycol (PEG). The waste products dialyze into the PEG leaving isolated DNA. The remaining DNA has been prepared with fragments containing more than 160 kb. The isolated DNA has been used in conventional protocols without effect on the protocol.

  11. Nucleic acid isolation process

    DOEpatents

    Longmire, Jonathan L.; Lewis, Annette K.; Hildebrand, Carl E.

    1990-01-01

    A method is provided for isolating DNA from eukaryotic cell and flow sorted chromosomes. When DNA is removed from chromosome and cell structure, detergent and proteolytic digestion products remain with the DNA. These products can be removed with organic extraction, but the process steps associated with organic extraction reduce the size of DNA fragments available for experimental use. The present process removes the waste products by dialyzing a solution containing the DNA against a solution containing polyethylene glycol (PEG). The waste products dialyze into the PEG leaving isolated DNA. The remaining DNA has been prepared with fragments containing more than 160 kb. The isolated DNA has been used in conventional protocols without affect on the protocol.

  12. [Isolated anterior cervical hypertrichosis].

    PubMed

    Monteagudo, B; Cabanillas, M; de las Heras, C; Cacharrón, J M

    2009-01-01

    Anterior cervical hypertrichosis was described by Trattner and coworkers in 1991. It consists of a of hair at the anterior cervical level just above the laryngeal prominence. To date, only 28 cases of anterior cervical hypertrichosis have been reported. Although it is normally an isolated finding, it may be associated with mental retardation, hallux valgus, retinal disorders, other hair disorders, facial dysmorphism, or sensory and motor peripheral neuropathy. We report the case of a 27-year-old woman who presented with this condition as an isolated finding. PMID:19268113

  13. Sulphide Ga{sub x}Ge{sub 25-x}Sb{sub 10}S{sub 65(x=0,5)} sputtered films: Fabrication and optical characterizations of planar and rib optical waveguides

    SciTech Connect

    Charrier, J.; Henrio, F.; Bosc, D.; Anne, M. L.; Nazabal, V.; Charpentier, F.; Jouan, T.; Adam, J. L.; Lhermite, H.; Guin, J. P.

    2008-10-01

    We report the fabrication and the physical and optical characterizations of sulphide Ga{sub x}Ge{sub 25-x}Sb{sub 10}S{sub 65(x=0,5)} rib waveguides. High quality films fabricated on SiO{sub 2}/Si wafer substrates were obtained using the sputtering magnetron rf deposition method. The slab waveguides obtained without annealing present propagation losses of about 0.6 dB/cm at 1550 nm. These optical losses are not important for implementation in optical devices based on silicon-on-insulator or polymer, for instance, atomic force microscopy measurements revealed low interface roughness between the different media (substrate/film and film/air). Reactive ion etching was used to pattern rib waveguides between 2 and 300 {mu}m wide. The parameters were optimized to obtain a dry etching process that had low surface roughness, vertical sidewalls, etch depth of more than 1 {mu}m, and reasonable etching rate. This technique was used to fabricate Y optical junctions for optical interconnections on chalcogenide amorphous films. Their optical transmission was demonstrated by optical near field of guided modes and optical losses were measured and discussed.

  14. Biological Isolation Garment

    NASA Technical Reports Server (NTRS)

    1976-01-01

    A spinoff of astronaut's biological garment will allow hospital patients who are highly vulnerable to infection to leave their sterile habitats for several hours, carrying their germ free environment with them. Garments can be used in any of some 200 hospitals where isolation rooms are installed to treat leukemia.

  15. Isolated patellofemoral osteoarthritis

    PubMed Central

    Poolman, Rudolf W; van Kampen, Albert

    2010-01-01

    Background and purpose The optimal treatment for isolated patellofemoral osteoarthritis is unclear at present. We systematically reviewed the highest level of available evidence on the nonoperative and operative treatment of isolated patellofemoral osteoarthritis to develop an evidenced-based discussion of treatment options. Methods A systematic computerized database search (Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, MEDLINE (PubMed), and EMBASE) was performed in March 2009. The quality of the studies was assessed independently by two authors using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. Results We extracted data from 44 articles. The best available evidence for treatment of isolated patellofemoral osteoarthritis is sparse and of generally low methodological quality. Nonoperative treatment using physiotherapy (GRADE: high quality, weak recommendation for use), taping (GRADE: moderate quality, weak recommendation for use), or injection therapy (GRADE: very low quality, weak recommendation for use) may result in short-term relief. Joint-preserving surgical treatment may result in insufficient, unpredictable, or only short-term improvement (GRADE: low quality, weak recommendation against use). Total knee replacement with patellar resurfacing results in predictable and good, durable results (GRADE: low quality, weak recommendation for use). Outcome after patellofemoral arthroplasty in selected patients is good to excellent (GRADE: low quality, weak recommendation for use). Interpretation Methodologically good quality comparative studies, preferably using a patient-relevant outcome instrument, are needed to establish the optimal treatment strategy for patients with isolated patellofemoral osteoarthritis. PMID:20175647

  16. Chiral fiber optical isolator

    NASA Astrophysics Data System (ADS)

    Kopp, Victor I.; Zhang, Guoyin; Zhang, Sheng; Genack, Azriel Z.; Neugroschl, Dan

    2009-02-01

    We propose an in-fiber chiral optical isolator based on chiral fiber polarizer technology and calculate its performance by incorporating the magnetic field into the scattering matrix. The design will be implemented in a special preform, which is passed through a miniature heat zone as it is drawn and twisted. The birefringence of the fiber is controlled by adjusted the diameter of a dual-core optical fiber. By adjusting the twist, the fiber can convert linear to circular polarization and reject one component of circular polarization. In the novel central portion of the isolator, the fiber diameter is large. The effective birefringence of the circular central core with high Verdet constant embedded in an outer core of slightly smaller index of refraction is small. The central potion is a non-reciprocal polarization converter which passes forward traveling left circularly polarized (LCP) light as LCP, while converting backward propagating LCP to right circularly polarized (RCP) light. Both polarizations of light traveling backwards are scattered out of the isolator. Since it is an all-glass structure, we anticipate that the isolator will be able to handle several watts of power and will be environmentally robust.

  17. Biological isolation garment

    NASA Technical Reports Server (NTRS)

    Spross, F. R.

    1968-01-01

    Biological Isolation Garment /BIG/ is a one-piece loose fitting garment fabricated from a tightly woven, permeable, 100 percent-cotton fabric. Its headpiece, incorporates an integral oronsal respirator with 0.3-micron-particle filters, and a full width visor. All fabrication seams are sealed on the inside of the garment.

  18. Breaking Down Racial Isolation.

    ERIC Educational Resources Information Center

    Foster, Lloyd A.

    1989-01-01

    Describes the "Across the Lines" project involving an interchange between students and teachers of two racially isolated schools in the Hartford (Connecticut) area. A racial mix of 50/50 was achieved through planned science museum visits, randomly paired pen pals, and an MCI electronic mail connection between schools. (MLH)

  19. Isolating Triggered Star Formation

    SciTech Connect

    Barton, Elizabeth J.; Arnold, Jacob A.; Zentner, Andrew R.; Bullock, James S.; Wechsler, Risa H.; /KIPAC, Menlo Park /SLAC

    2007-09-12

    Galaxy pairs provide a potentially powerful means of studying triggered star formation from galaxy interactions. We use a large cosmological N-body simulation coupled with a well-tested semi-analytic substructure model to demonstrate that the majority of galaxies in close pairs reside within cluster or group-size halos and therefore represent a biased population, poorly suited for direct comparison to 'field' galaxies. Thus, the frequent observation that some types of galaxies in pairs have redder colors than 'field' galaxies is primarily a selection effect. We use our simulations to devise a means to select galaxy pairs that are isolated in their dark matter halos with respect to other massive subhalos (N= 2 halos) and to select a control sample of isolated galaxies (N= 1 halos) for comparison. We then apply these selection criteria to a volume-limited subset of the 2dF Galaxy Redshift Survey with M{sub B,j} {le} -19 and obtain the first clean measure of the typical fraction of galaxies affected by triggered star formation and the average elevation in the star formation rate. We find that 24% (30.5 %) of these L* and sub-L* galaxies in isolated 50 (30) h{sup -1} kpc pairs exhibit star formation that is boosted by a factor of {approx}> 5 above their average past value, while only 10% of isolated galaxies in the control sample show this level of enhancement. Thus, 14% (20 %) of the galaxies in these close pairs show clear triggered star formation. Our orbit models suggest that 12% (16%) of 50 (30) h{sup -1} kpc close pairs that are isolated according to our definition have had a close ({le} 30 h{sup -1} kpc) pass within the last Gyr. Thus, the data are broadly consistent with a scenario in which most or all close passes of isolated pairs result in triggered star formation. The isolation criteria we develop provide a means to constrain star formation and feedback prescriptions in hydrodynamic simulations and a very general method of understanding the importance of

  20. Modeling the relationship between scanned rump and 12th-rib fat in young temperate and tropical bovines: model development and evaluation.

    PubMed

    Walmsley, B J; Wolcott, M L; McPhee, M J

    2010-05-01

    A decision support tool for predicting subcutaneous fat depths called BeefSpecs, based on the Davis growth model (DGM), has been developed by the Cooperative Research Centre for Beef Genetic Technologies. Currently, the DGM predicts 12th-rib fat thickness (RFT, mm). To allow predictions of fat thickness at the P8 rump (P8FT, mm) site, the standard carcass fat measurement in the Australian beef industry, a relationship was developed between ultrasound RFT and P8FT in steers and heifers from temperate (Angus, Hereford, Shorthorn, and Murray Grey) and tropical (Brahman, Belmont Red, and Santa Gertrudis) breed types. Model development involved fitting various combinations of sex, breed type (BrT), BW, age, and RFT to produce 6 models. The models were challenged with data from 3 independent data sets: 1) Angus steers from 2.4 generations of divergent selection for and against residual feed intake; 2) 2 tropically adapted genotypes [Brahman and tropically adapted composites (combinations of Belmont Red, Charbray, Santa Gertrudis, Senepol, and Brahman breeds)]; and 3) a study using sires from Charolais, Limousin, Belgian Blue, and Black and Red Wagyu breeds and 3 genetic lines of Angus to create divergence in progeny in terms of genetic potential for intramuscular fat percent and retail beef yield. When challenged with data from Angus cattle, the mean biases (MB, mm) for models A to F were -1.23, -0.56, -0.56, -0.02, 0.14, and 0.04, and the root mean square errors of predictions (mm) were 1.53, 0.97, 0.97, 0.92, 0.93, and 0.91, respectively. When challenged with data from Brahman cattle, MB were 0.04, -0.22, -0.14, 0.05, -0.11, and 0.02 and root mean square errors of predictions were 1.30, 1.29, 1.27, 1.23, 1.37, and 1.29, respectively. Generally, model accuracy indicated by MB tended to be less for model E, which contained age rather than BW as a covariate. Models B and C were generally robust when challenged with data from Angus, Brahman, and Tropical Composite cattle

  1. Method for isolating nucleic acids

    DOEpatents

    Hurt, Jr., Richard Ashley; Elias, Dwayne A.

    2015-09-29

    The current disclosure provides methods and kits for isolating nucleic acid from an environmental sample. The current methods and compositions further provide methods for isolating nucleic acids by reducing adsorption of nucleic acids by charged ions and particles within an environmental sample. The methods of the current disclosure provide methods for isolating nucleic acids by releasing adsorbed nucleic acids from charged particles during the nucleic acid isolation process. The current disclosure facilitates the isolation of nucleic acids of sufficient quality and quantity to enable one of ordinary skill in the art to utilize or analyze the isolated nucleic acids for a wide variety of applications including, sequencing or species population analysis.

  2. Bacillus odysseyi isolate

    NASA Technical Reports Server (NTRS)

    Venkateswaran, Kasthuri (Inventor); La Duc, Myron Thomas (Inventor)

    2007-01-01

    The present invention relates to discovery and isolation of a biologically pure culture of a Bacillus odysseyi isolate with high adherence and sterilization resistant properties. B. odysseyi is a round spore forming Bacillus species that produces an exosporium. This novel species has been characterized on the basis of phenotypic traits, 16S rDNA sequence analysis and DNA-DNA hybridization. According to the results of these analyses, this strain belongs to the genus Bacillus and the type strain is 34hs-1.sup.T (=ATCC PTA-4993.sup.T=NRRL B-30641.sup.T=NBRC 100172.sup.T). The GenBank accession number for the 16S rDNA sequence of strain 34hs-1.sup.T is AF526913.

  3. High voltage isolation transformer

    NASA Technical Reports Server (NTRS)

    Clatterbuck, C. H.; Ruitberg, A. P. (Inventor)

    1985-01-01

    A high voltage isolation transformer is provided with primary and secondary coils separated by discrete electrostatic shields from the surfaces of insulating spools on which the coils are wound. The electrostatic shields are formed by coatings of a compound with a low electrical conductivity which completely encase the coils and adhere to the surfaces of the insulating spools adjacent to the coils. Coatings of the compound also line axial bores of the spools, thereby forming electrostatic shields separating the spools from legs of a ferromagnetic core extending through the bores. The transformer is able to isolate a high constant potential applied to one of its coils, without the occurrence of sparking or corona, by coupling the coatings, lining the axial bores to the ferromagnetic core and by coupling one terminal of each coil to the respective coating encasing the coil.

  4. Pump isolation valve

    DOEpatents

    Kinney, Calvin L.; Wetherill, Todd M.

    1983-08-02

    The pump isolation valve provides a means by which the pump may be selectively isolated from the remainder of the coolant system while being compatible with the internal hydraulic arrangement of the pump during normal operation of the pump. The valve comprises a valve cylinder disposed around the pump and adjacent to the last pump diffuser with a turning vane attached to the lower end of the valve cylinder in a manner so as to hydraulically match with the discharge diffuser. The valve cylinder is connected to a drive means for sliding the valve cylinder relative to the diffuser support cylinder so as to block flow in either direction through the discharge diffuser when the valve is in the closed position and to aid in the flow of the coolant from the discharge diffuser by means of the turning vane when the valve is in the open position.

  5. Ultrasonic thermometer isolation standoffs

    DOEpatents

    Arave, Alvin E.

    1977-01-01

    A method is provided for minimizing sticking of the transmission line to the protective sheath and preventing noise echoes from interfering with signal echoes in an improved high temperature ultrasonic thermometer which includes an ultrasonic transmission line surrounded by a protective sheath. Small isolation standoffs are mounted on the transmission line to minimize points of contact between the transmission line and the protective sheath, the isolation standoffs serving as discontinuities mounted on the transmission line at locations where a signal echo is desired or where an echo can be tolerated. Consequently any noise echo generated by the sticking of the standoff to the protective sheath only adds to the amplitude of the echo generated at the standoff and does not interfere with the other signal echoes.

  6. Cycle isolation monitoring

    SciTech Connect

    Svensen, L.M. III; Zeigler, J.R.; Todd, F.D.; Alder, G.C.

    2009-07-15

    There are many factors to monitor in power plants, but one that is frequently overlooked is cycle isolation. Often this is an area where plant personnel can find 'low hanging fruit' with great return on investment, especially high energy valve leakage. This type of leakage leads to increased heat rate, potential valve damage and lost generation. The fundamental question to ask is 'What is 100 Btu/kW-hr of heat rate worth to your plant? On a 600 MW coal-fired power plant, a 1% leakage can lead to an 81 Btu/kW-hr impact on the main steam cycle and a 64 Btu/kW-hr impact on the hot reheat cycle. The article gives advice on methods to assist in detecting leaking valves and to monitor cycle isolation. A software product, TP. Plus-CIM was designed to estimate flow rates of potentially leaking valves.

  7. Genetics of population isolates.

    PubMed

    Arcos-Burgos, M; Muenke, M

    2002-04-01

    Genetic isolates, as shown empirically by the Finnish, Old Order Amish, Hutterites, Sardinian and Jewish communities among others, represent a most important and powerful tool in genetically mapping inherited disorders. The main features associated with that genetic power are the existence of multigenerational pedigrees which are mostly descended from a small number of founders a short number of generations ago, environmental and phenotypic homogeneity, restricted geographical distribution, the presence of exhaustive and detailed records correlating individuals in very well ascertained pedigrees, and inbreeding as a norm. On the other hand, the presence of a multifounder effect or admixture among divergent populations in the founder time (e.g. the Finnish and the Paisa community from Colombia) will theoretically result in increased linkage disequilibrium among adjacent loci. The present review evaluates the historical context and features of some genetic isolates with emphasis on the basic population genetic concepts of inbreeding and genetic drift, and also the state-of-the-art in mapping traits, both Mendelian and complex, on genetic isolates. PMID:12030885

  8. Isolation of neuromelanin granules.

    PubMed

    Tribl, Florian

    2008-12-01

    Neuromelanin granules are pigmented organelles in the human midbrain that give name to a brain area, substantia nigra pars compacta, which macroscopically appears as a dark brown region in the midbrain due to the insoluble pigment neuromelanin. The substantia nigra pars compacta massively degenerates in Parkinson's disease and gives rise to severely disabling movement symptoms. It has been suggested that neuromelanin granules play an important role in the neurodegenerative events in Parkinson's disease: redox-active iron is bound to neuromelanin and thereby retained within this compartment, but in Parkinson's disease it is thought to be increasingly released into the cytosol, promoting oxidative stress. This unit includes a methodological workflow for the isolation of neuromelanin granules from the human midbrain. This top-down approach (describes an approach that reduces the complexity of the sample stepwise from the level of tissue to cell, and from cell to organelle) encompasses the organelle isolation by sequential density gradient centrifugation and the assessment of the isolation efficacy by western blotting. PMID:19085988

  9. Isolated persistent hypermethioninemia.

    PubMed Central

    Mudd, S H; Levy, H L; Tangerman, A; Boujet, C; Buist, N; Davidson-Mundt, A; Hudgins, L; Oyanagi, K; Nagao, M; Wilson, W G

    1995-01-01

    New information has been obtained on 30 patients with isolated persistent hypermethioninemia, most of them previously unreported. Biopsies to confirm the presumptive diagnosis of partially deficient activity of ATP: L-methionine S-adenosyltransferase (MAT; E.C.2.5.1.6) in liver were not performed on most of these patients. However, none showed the clinical findings or the extreme elevations of serum folate previously described in other patients with isolated hypermethioninemia considered not to have hepatic MAT deficiency. Patients ascertained on biochemical grounds had no neurological abnormalities, and 27/30 had IQs or Bayley development-index scores within normal limits or were judged to have normal mental development. Methionine transamination metabolites accumulated abnormally only when plasma methionine concentrations exceeded 300-350 microM and did so more markedly after 0.9 years of age. Data were obtained on urinary organic acids as well as plasma creatinine concentrations. Patterns of inheritance of isolated hypermethioninemia were variable. Considerations as to the optimal management of this group of patients are discussed. PMID:7573050

  10. Rare Form of Erdheim-Chester Disease Presenting with Isolated Central Skeletal Lesions Treated with a Combination of Alfa-Interferon and Zoledronic Acid

    PubMed Central

    Bulycheva, E. N.; Baykov, V. V.; Zaraĭskiĭ, M. I.; Salogub, G. N.

    2015-01-01

    Erdheim-Chester disease (ECD) represents a clonal non-Langerhans histiocytosis, which manifests under an extensive variety of clinical symptoms. This creates a challenge for the physician, who is required to recognize and diagnose the disease in the early stages. Despite this considerable challenge, in the last decade there has been a dramatic increase in ECD diagnoses, in most part due to an increasing awareness of this rare disorder. Involvement of the axial skeleton is exclusively uncommon with no official recommendations for the treatment of the bone lesions. Here, we present a case report of a young male patient with isolated lesions of the spine, ribs, and pelvis, who was successfully treated with a combination therapy of alfa-interferon and zoledronic acid. PMID:25949835

  11. Examination of the Lunatic fringe and Uncx4.1 expression by whole-mount in situ hybridization in the embryo of the CKH-Jsr (jumbled spine and ribs) mouse.

    PubMed

    Okano, Shinya; Asano, Atsushi; Sasaki, Nobuya; Kon, Yasuhiro; Watanabe, Tomomasa; Agui, Takashi

    2005-02-01

    The CKH-Jsr (jumbled spine and ribs) mouse was found as a spontaneous mutant with malformation of vertebrae, that is, a short trunk and kinky tail. We examined Lunatic Fringe (Lfng) and Uncx4.1 expression in the presomitic mesoderm (PSM) and somites of Jsr-mutant (CKH-Jsr/+) embryos to elucidate pathogenesis of the Jsr mutation. Expression pattern of Lfng in the PSM of Jsr-mutant embryos was similar to that of the normal (C57BL/6) embryos. However, expression pattern of Uncx4.1 in the somites of Jsr-mutant embryos was impaired to be irregular and mosaic, suggesting that the anterior-posterior (A-P) polarity is disordered in the Jsr mutant. These results indicate that the Jsr mutation disrupts the A-P polarity of somites during the somitogenesis without altering Lfng expression pattern in the PSM. PMID:15822856

  12. How isolated is Antarctica?

    PubMed

    Clarke, Andrew; Barnes, David K A; Hodgson, Dominic A

    2005-01-01

    The traditional view of Antarctica and the surrounding Southern Ocean as an isolated system is now being challenged by the recent discovery at the Antarctic Peninsula of adult spider crabs Hyas areneus from the North Atlantic and of larvae of subpolar marine invertebrates. These observations question whether the well described biogeographical similarities between the benthic fauna of the Antarctic Peninsula and the Magellan region of South America result from history (the two regions were once contiguous), or from a previously unrecognized low level of faunal exchange. Such exchange might be influenced by regional climate change, and also exacerbated by changes in human impact. PMID:16701330

  13. Nucleic acid isolation process

    SciTech Connect

    Longmire, J.L.; Lewis, A.K.; Hildebrand, C.E.

    1990-05-01

    This patent describes a process for preparing DNA from cellular materials for use in genetic studies of eukaryotic systems, a process for isolating DNA fragments from proteolytic digestion products and detergent products in a solution with the DNA fragments produced in stripping undesired cellular constituents from the DNA. It comprises the step of dialyzing a solution containing the DNA fragments, detergent products, and proteolytic digestion products against a solution containing PEG for a time effective to yield DNA sufficiently pure of the genetic studies.

  14. Investigation of mercury thruster isolators

    NASA Technical Reports Server (NTRS)

    Mantenieks, M. A.

    1973-01-01

    Mercury ion thruster isolator lifetime tests were performed using different isolator materials and geometries. Tests were performed with and without the flow of mercury through the isolators in an oil diffusion pumped vacuum facility and cryogenically pumped bell jar. The onset of leakage current in isolators occurred in time intervals ranging from a few hours to many hundreds of hours. In all cases, surface contamination was responsible for the onset of leakage current and subsequent isolator failure. Rate of increase of leakage current and the leakage current level increased approximately exponentially with isolator temperature. Careful attention to shielding techniques and the elimination of sources of metal oxides appear to have eliminated isolator failures as a thruster life limiting mechanism.

  15. Isolation and characterization of ex vivo expanded mesenchymal stem cells obtained from a surgical patient

    PubMed Central

    HUANG, JIA; SHA, HUIFAN; WANG, GUAN; BAO, GUOLIANG; LU, SHUN; LUO, QINGQUAN; TAN, QIANG

    2015-01-01

    The aim of the present study was to investigate the morphological characteristics and pluripotent differentiation potential of human bone marrow mesenchymal stem cells (hBMMSCs) in vitro and in vivo. Bone marrow cells were isolated from a rib fragment of an adult surgical patient, hBMMSCs were isolated based on plastic adherence and expanded ex vivo and phenotyping was performed. Pluripotent differentiation assays for adipogenesis, myogenesis and osteogenesis were conducted. Hematopoietic reconstruction of sublethally irradiated nude mice was performed by infusion of hBMMSCs. The gene expression profiles of early and late hBMMSCs were examined. The rate of CD31-positive cells was 31.1% in passage (P)4 hBMMSCs and 18.6% in P10 hBMMSCs. CD105 and CD106 were expressed in 99 and 95% of P25 hBMMSCs, respectively. Lipid droplets appeared at day 18 post induction. For osteogenesis, palpable masses were grossly observed from day 35 post inoculation of hBMMSCs. Hematoxylin and eosin staining further revealed chondrocytes and bone tissues. For myogenesis, at day six post subcutaneous inoculation, hBMMSCs differentiated into myocytes and were positive for myoglobin and MyoD1. In irradiated nude mice reconstituted by hBMMSCs, the white blood cell count briefly decreased following irradiation; however, it gradually recovered. In the irradiated nude mice reconstituted with hBMMSCs, CD45- and CD34-positive cells were detected 72 h post induction. Gene microarray analysis of P7 and P57 hBMMSCs demonstrated that 20 genes were upregulated >2 fold and 40 genes were downregulated >2 fold in P57 hBMMSCs. In conclusion, the isolated HBMMSCs possessed pluripotent differentiation potential and it was feasible and safe to use hBMMSCs within 30 passages. PMID:25376882

  16. ISOLATION OF MOUSE NEUTROPHILS

    PubMed Central

    Swamydas, Muthulekha; Luo, Yi; Dorf, Martin E.; Lionakis, Michail S.

    2015-01-01

    Neutrophils represent the first line of defense against bacterial and fungal pathogens. Indeed, patients with inherited and acquired qualitative and quantitative neutrophil defects are at high risk for developing bacterial and fungal infections and suffering adverse outcomes from these infections. Therefore, research aiming at defining the molecular factors that modulate neutrophil effector function under homeostatic conditions and during infection is essential for devising strategies to augment neutrophil function and improve the outcome of infected individuals. This unit describes a reproducible density gradient centrifugation-based protocol that can be applied in any laboratory to harvest large numbers of highly enriched and highly viable neutrophils from the bone marrow of mice both at the steady state and following infection with Candida albicans as described in UNIT 19.6. In another protocol, we also present a method that combines gentle enzymatic tissue digestion with a positive immunomagnetic selection technique or Fluorescence-activated cell sorting (FACS) to harvest highly pure and highly viable preparations of neutrophils directly from mouse tissues such as the kidney, the liver or the spleen. Finally, methods for isolating neutrophils from mouse peritoneal fluid and peripheral blood are included. Mouse neutrophils isolated by these protocols can be used for examining several aspects of cellular function ex vivo including pathogen binding, phagocytosis and killing, neutrophil chemotaxis, oxidative burst, degranulation and cytokine production, and for performing neutrophil adoptive transfer experiments. PMID:26237011

  17. Mechanical strain isolator mount

    NASA Technical Reports Server (NTRS)

    James, Gordon E. (Inventor)

    1991-01-01

    Certain devices such as optical instruments must preserve their alignmental integrity while being subjected to mechanical strain. A mechanical strain isolator mount is provided to preserve the alignmental integrity of an alignment sensitive instrument. An alignment sensitive instrument is mounted on a rectangular base. Flexural legs are connected at their proximal ends to the rectangular base. Flexural legs are also spaced parallel to the sides. Mounting pads are connected to the legs at the distal end and the mechanical strain isolator mount is attached to the substrate by means of threaded bolts. When a mounting pad and its respective leg is subjected to lateral strain in either the X or Y direction via the substrate, the respective leg relieves the strain by bending in the direction of the strain. An axial strain on a mounting pad in the Z direction is relieved by a rotational motion of the legs in the direction of the strain. When the substrate is stress free, the flexural legs return to their original condition and thus preserve the original alignment integrity of the alignment sensitive instrument.

  18. The Role of Social Isolation in Suicide.

    ERIC Educational Resources Information Center

    Trout, Deborah L.

    1980-01-01

    Reviews the literature which relates to the role of social isolation in suicide. Major areas reviewed include theories on suicide and social isolation, measures of social isolation, and empirical studies which concern the relationship of social isolation to suicide. (Author)

  19. Isolated resonator gyroscope with isolation trimming using a secondary element

    NASA Technical Reports Server (NTRS)

    Challoner, A. Dorian (Inventor); Shcheglov, Kirill V. (Inventor)

    2006-01-01

    The present invention discloses a resonator gyroscope including an isolated resonator. One or more flexures support the isolated resonator and a baseplate is affixed to the resonator by the flexures. Drive and sense elements are affixed to the baseplate and used to excite the resonator and sense movement of the gyroscope. In addition, at least one secondary element (e.g., another electrode) is affixed to the baseplate and used for trimming isolation of the resonator. The resonator operates such that it transfers substantially no net momentum to the baseplate when the resonator is excited. Typically, the isolated resonator comprises a proof mass and a counterbalancing plate.

  20. Material isolation enclosure

    DOEpatents

    Martell, Calvin J.; Dahlby, Joel W.; Gallimore, Bradford F.; Comer, Bob E.; Stone, Water A.; Carlson, David O.

    1993-01-01

    An enclosure similar to a glovebox for isolating materials from the atmosphere, yet allowing a technician to manipulate the materials and also apparatus which is located inside the enclosure. A portion of a wall of the enclosure is comprised of at least one flexible curtain. An opening defined by a frame is provided for the technician to insert his hands and forearms into the enclosure. The frame is movable in one plane, so that the technician has access to substantially all of the working interior of the enclosure. As the frame is moved by the technician, while he accomplishes work inside the enclosure, the curtain moves such that the only opening through the enclosure wall is the frame. In a preferred embodiment, where a negative pressure is maintained inside the enclosure, the frame is comprised of airfoils so that turbulence is reduced, thereby enhancing material retention within the box.

  1. Material isolation enclosure

    DOEpatents

    Martell, C.J.; Dahlby, J.W.; Gallimore, B.F.; Comer, B.E.; Stone, W.A.; Carlson, D.O.

    1993-04-27

    An enclosure is described, similar to a glove box, for isolating materials from the atmosphere, yet allowing a technician to manipulate the materials and also apparatus which is located inside the enclosure. A portion of a wall of the enclosure is comprised of at least one flexible curtain. An opening defined by a frame is provided for the technician to insert his hands and forearms into the enclosure. The frame is movable in one plane, so that the technician has access to substantially all of the working interior of the enclosure. As the frame is moved by the technician, while he accomplishes work inside the enclosure, the curtain moves such that the only opening through the enclosure wall is the frame. In a preferred embodiment, where a negative pressure is maintained inside the enclosure, the frame is comprised of airfoils so that turbulence is reduced, thereby enhancing material retention within the box.

  2. Isolated post resonator mesogyroscope

    NASA Technical Reports Server (NTRS)

    Challoner, Dorian; Peay, Chris; Wellman, Joanne; Shcheglov, Kirill; Hayworth, Ken; Wiberg, Dean; Yee, Karl; Sipppola, Clayton

    2004-01-01

    A new symmetric vibratory gyroscope principle has been devised in which a central post proof mass is counter-rocked against an outer sensing plate such that the motion is isolated from the gyroscope case. Prototype gyroscopes have been designed and fabricated with micromachined silicon at mesoscale (20-cm resonator width), vs. microscale (e.g., 2-mm resonator width) to achieve higher sensitivity and machined precision. This novel mesogyro design arose out of an ongoing technical cooperation between JPL and Boeing begun in 1997 to advance the design of micro-inertial sensors for low-cost space applications. This paper describes the theory of operation of the mesogyro and relationships with other vibratory gyroscopes, the mechanical design, closed loop electronics design, bulk silicon fabrication and packaged gyroscope assembly and test methods. The initial packaged prototype test results are reported for what is believed to be the first silicon mesogyroscope.

  3. Thermally isolated well instruments

    SciTech Connect

    Engelder, P.D.

    1984-04-03

    A well instrument is isolated from the high temperatures of a surrounding earth formation by enclosing the instrument within a heat insulative jacket structure, preferably a dewar having spaced walls with a vacuum therebetween, with a heat sink contained in the jacket above the instrument assembly, and with a heat pipe extending upwardly from the instrument assembly to the heat sink and containing a fluid which by evaporation at a lower point and condensation at a higher point will conduct heat upwardly from the instrument assembly to the heat sink but not downwardly therebetween. The heat pipe preferably projects upwardly beyond a top portion of the insulating jacket to the location of a convector element which is exposed to the temperature of fluid or air at the outside of the insulating jacket to transmit heat from within the jacket to its exterior but not in a reverse direction.

  4. Magnetically coupled signal isolator

    NASA Technical Reports Server (NTRS)

    Black, Jr., William C. (Inventor); Hermann, Theodore M. (Inventor)

    2001-01-01

    A current determiner having an output at which representations of input currents are provided having an input conductor for the input current and a current sensor supported on a substrate electrically isolated from one another but with the sensor positioned in the magnetic fields arising about the input conductor due to any input currents. The sensor extends along the substrate in a direction primarily perpendicular to the extent of the input conductor and is formed of at least a pair of thin-film ferromagnetic layers separated by a non-magnetic conductive layer. The sensor can be electrically connected to electronic circuitry formed in the substrate including a nonlinearity adaptation circuit to provide representations of the input currents of increased accuracy despite nonlinearities in the current sensor, and can include further current sensors in bridge circuits.

  5. Isolated Northern Dunes

    NASA Technical Reports Server (NTRS)

    2005-01-01

    [figure removed for brevity, see original site]

    Our topic for the weeks of April 4 and April 11 is dunes on Mars. We will look at the north polar sand sea and at isolated dune fields at lower latitudes. Sand seas on Earth are often called 'ergs,' an Arabic name for dune field. A sand sea differs from a dune field in two ways: 1) a sand sea has a large regional extent, and 2) the individual dunes are large in size and complex in form.

    This VIS image was taken at 81 degrees North latitude during Northern spring. In this region, the dunes are isolated from each other. The dunes are just starting to emerge from the winter frost covering appearing dark with bright crests. These dunes are located on top of ice.

    Image information: VIS instrument. Latitude 82.1, Longitude 191.3 East (168.7 West). 19 meter/pixel resolution.

    Note: this THEMIS visual image has not been radiometrically nor geometrically calibrated for this preliminary release. An empirical correction has been performed to remove instrumental effects. A linear shift has been applied in the cross-track and down-track direction to approximate spacecraft and planetary motion. Fully calibrated and geometrically projected images will be released through the Planetary Data System in accordance with Project policies at a later time.

    NASA's Jet Propulsion Laboratory manages the 2001 Mars Odyssey mission for NASA's Office of Space Science, Washington, D.C. The Thermal Emission Imaging System (THEMIS) was developed by Arizona State University, Tempe, in collaboration with Raytheon Santa Barbara Remote Sensing. The THEMIS investigation is led by Dr. Philip Christensen at Arizona State University. Lockheed Martin Astronautics, Denver, is the prime contractor for the Odyssey project, and developed and built the orbiter. Mission operations are conducted jointly from Lockheed Martin and from JPL, a division of the California Institute of Technology in Pasadena.

  6. A hybrid base isolation system

    SciTech Connect

    Hart, G.C.; Lobo, R.F.; Srinivasan, M.; Asher, J.W.

    1995-12-01

    This paper proposes a new analysis procedure for hybrid base isolation buildings when considering the displacement response of a base isolated building to wind loads. The system is considered hybrid because of the presence of viscous dampers in the building above the isolator level. The proposed analysis approach incorporates a detailed site specific wind study combined with a dynamic nonlinear analysis of the building response.

  7. Cotton roll isolation versus Vac-Ejector isolation.

    PubMed

    Wood, A J; Saravia, M E; Farrington, F H

    1989-01-01

    A visible-light-cured, white pit-and-fissure sealant was applied to 523 teeth in school children using either cotton rolls or a VacEjector for isolation. After a minimum of six months, the patients were recalled and the retention of the sealants was evaluated. No significant difference in sealant retention was found between the two isolation methods. PMID:2530257

  8. Clinically isolated syndromes.

    PubMed

    Miller, David H; Chard, Declan T; Ciccarelli, Olga

    2012-02-01

    Clinically isolated syndrome (CIS) is a term that describes a first clinical episode with features suggestive of multiple sclerosis (MS). It usually occurs in young adults and affects optic nerves, the brainstem, or the spinal cord. Although patients usually recover from their presenting episode, CIS is often the first manifestation of MS. The most notable risk factors for MS are clinically silent MRI lesions and CSF oligoclonal bands; weak or uncertain risk factors include vitamin D deficiency, Epstein-Barr virus infection, smoking, HLA genes, and miscellaneous immunological abnormalities. Diagnostic investigations including MRI aim to exclude alternative causes and to define the risk for MS. MRI findings incorporated into diagnostic criteria in the past decade enable MS to be diagnosed at or soon after CIS presentation. The course of MS after CIS is variable: after 15-20 years, a third of patients have a benign course with minimal or no disability and a half will have developed secondary progressive MS with increasing disability. Prediction of the long-term course at disease onset is unreliable. Disease-modifying treatments delay the development from CIS to MS. Their use in CIS is limited by uncertain long-term clinical prognosis and treatment benefits and adverse effects, although they have the potential to prevent or delay future tissue damage, including demyelination and axonal loss. Targets for future therapeutic progress are to achieve safe and effective long-term immunomodulation with neuroprotection and repair. PMID:22265211

  9. Vibration isolation mounting system

    NASA Technical Reports Server (NTRS)

    Carter, Sam D. (Inventor); Bastin, Paul H. (Inventor)

    1995-01-01

    A system is disclosed for mounting a vibration producing device onto a spacecraft structure and also for isolating the vibration forces thereof from the structure. The system includes a mount on which the device is securely mounted and inner and outer rings. The rings and mount are concentrically positioned. The system includes a base (secured to the structure) and a set of links which are interconnected by a set of torsion bars which allow and resist relative rotational movement therebetween. The set of links are also rotatably connected to a set of brackets which are rigidly connected to the outer ring. Damped leaf springs interconnect the inner and outer rings and the mount allow relative translational movement therebetween in X and Y directions. The links, brackets and base are interconnected and configured so that they allow and resist translational movement of the device in the Z direction so that in combination with the springs they provide absorption of vibrational energy produced by the device in all three dimensions while providing rotational stiffness about all three axes to prevent undesired rotational motions.

  10. New Ventilated Isolation Cage

    PubMed Central

    Cook, Reginald O.

    1968-01-01

    A multifunction lid has been developed for a commercially available transparent animal cage which permits feeding, watering, viewing, long-term holding, and local transport of laboratory rodents on experiment while isolating the surrounding environment. The cage is airtight except for its inlet and exhaust high-efficiency particulate air filters, and it is completely steam-sterilizable. Opening of the cage's feed and water ports causes an inrush of high velocity air which prevents back-migration of aerosols and permits feeding and watering while eliminating need for chemical vapor decontamination. Ventilation system design permits the holding in adjacent cages of animals infected with different organisms without danger of cross-contamination; leaves the animal room odor-free; reduces required bedding changes to twice a month or less, and provides investigators with capability to control precisely individual cage ventilation rates. Forty-eight cages can be conveniently placed on a standard NIH “shoebox” cage rack (60 inches wide × 28 inches deep × 74 inches high) fitted with a simple manifold exhaust system. The entire system is mobile, requiring only an electrical power outlet. Principal application of the caging system is in the area of preventing exposure of animal caretakers to pathogenic substances associated with the animal host, and in reducing handling of animals and their exposure to extraneous contamination. Images Fig. 1 Fig. 2 Fig. 3 Fig. 4 Fig. 5 Fig. 9 PMID:5659368

  11. Transverse Magnetic Field Propellant Isolator

    NASA Technical Reports Server (NTRS)

    Foster, John E.

    2000-01-01

    An alternative high voltage isolator for electric propulsion and ground-based ion source applications has been designed and tested. This design employs a transverse magnetic field that increases the breakdown voltage. The design can greatly enhance the operating range of laboratory isolators used for high voltage applications.

  12. Isolated transfer of analog signals

    NASA Technical Reports Server (NTRS)

    Bezdek, T.

    1974-01-01

    Technique transfers analog signal levels across high isolation boundary without circuit performance being affected by magnetizing reactance or leakage inductance. Transfers of analog information across isolated boundary are made by interrupting signal flow, with switch, in such a manner as to produce alternating signal which is applied to transformer.

  13. Reactor core isolation cooling system

    DOEpatents

    Cooke, F.E.

    1992-12-08

    A reactor core isolation cooling system includes a reactor pressure vessel containing a reactor core, a drywell vessel, a containment vessel, and an isolation pool containing an isolation condenser. A turbine is operatively joined to the pressure vessel outlet steamline and powers a pump operatively joined to the pressure vessel feedwater line. In operation, steam from the pressure vessel powers the turbine which in turn powers the pump to pump makeup water from a pool to the feedwater line into the pressure vessel for maintaining water level over the reactor core. Steam discharged from the turbine is channeled to the isolation condenser and is condensed therein. The resulting heat is discharged into the isolation pool and vented to the atmosphere outside the containment vessel for removing heat therefrom. 1 figure.

  14. Reactor core isolation cooling system

    DOEpatents

    Cooke, Franklin E.

    1992-01-01

    A reactor core isolation cooling system includes a reactor pressure vessel containing a reactor core, a drywell vessel, a containment vessel, and an isolation pool containing an isolation condenser. A turbine is operatively joined to the pressure vessel outlet steamline and powers a pump operatively joined to the pressure vessel feedwater line. In operation, steam from the pressure vessel powers the turbine which in turn powers the pump to pump makeup water from a pool to the feedwater line into the pressure vessel for maintaining water level over the reactor core. Steam discharged from the turbine is channeled to the isolation condenser and is condensed therein. The resulting heat is discharged into the isolation pool and vented to the atmosphere outside the containment vessel for removing heat therefrom.

  15. High performance rotational vibration isolator

    NASA Astrophysics Data System (ADS)

    Sunderland, Andrew; Blair, David G.; Ju, Li; Golden, Howard; Torres, Francis; Chen, Xu; Lockwood, Ray; Wolfgram, Peter

    2013-10-01

    We present a new rotational vibration isolator with an extremely low resonant frequency of 0.055 ± 0.002 Hz. The isolator consists of two concentric spheres separated by a layer of water and joined by very soft silicone springs. The isolator reduces rotation noise at all frequencies above its resonance which is very important for airborne mineral detection. We show that more than 40 dB of isolation is achieved in a helicopter survey for rotations at frequencies between 2 Hz and 20 Hz. Issues affecting performance such as translation to rotation coupling and temperature are discussed. The isolator contains almost no metal, making it particularly suitable for electromagnetic sensors.

  16. Luteimonas soli sp. nov., isolated from farmland soil.

    PubMed

    Wang, Xiang; Yang, Hong-Xing; Zhang, Ying-Kun; Zhu, Shi-Jun; Liu, Xiao-Wei; Zhang, Hao; Zhang, Chen-Fei; Zhao, Chao-Ran; Hu, Gang; Hong, Qing

    2015-12-01

    A yellow-pigmented bacterial strain, designated Y2T, was isolated from farmland soil in Bengbu, Anhui province, China. Cells of strain Y2T were Gram-stain-negative, strictly aerobic, non-motile and rod-shaped. Strain Y2T grew optimally at pH 7.0, 30 °C and in the presence of 2 % (w/v) NaCl. The DNA G+C content was 68.9 mol%. The major fatty acids (>5 %) were iso-C15 : 0, iso-C17 : 0, summed feature 9 (C16 : 0 10-methyl and/or iso-C17 : 1ω9c), iso-C11 : 0 3-OH and iso-C11 : 0. The major respiratory quinone was ubiquinone-8 (Q-8), and the major polar lipids were phosphatidylethanolamine, phosphatidylglycerol and diphosphatidylglycerol. Phylogenetic analysis of the 16S rRNA gene sequences showed that strain Y2T was most closely related to Luteimonas mephitis B1953/27.1T (99.1 % 16S rRNA gene sequence similarity), followed by Luteimonas lutimaris G3T (98.6 %), Luteimonas abyssi XH031T (96.2 %) and Luteimonas aquatica RIB1-20T (96.0 %). Strain Y2T exhibited low DNA-DNA relatedness with Luteimonas mephitis B1953/27.1T (43.6 ± 0.5 %) and Luteimonas lutimaris G3T (43.9 ± 2.1 %). On the basis of phenotypic, genotypic and phylogenetic evidence, strain Y2T represents a novel species of the genus Luteimonas, for which the name Luteimonas soli sp. nov. is proposed. The type strain is Y2T ( = ACCC 19799T = KCTC 42441T). PMID:26437920

  17. GOES-R Dual Isolation

    NASA Technical Reports Server (NTRS)

    Freesland, Doug; Carter, Delano; Chapel, Jim; Clapp, Brian; Howat, John; Krimchansky, Alexander

    2015-01-01

    The Geostationary Operational Environmental Satellite-R Series (GOES-R) is the first of the next generation geostationary weather satellites, scheduled for delivery in late 2015. GOES-R represents a quantum increase in Earth and solar weather observation capabilities, with 4 times the resolution, 5 times the observation rate, and 3 times the number of spectral bands for Earth observations. With the improved resolution, comes the instrument suite's increased sensitive to disturbances over a broad spectrum 0-512 Hz. Sources of disturbance include reaction wheels, thruster firings for station keeping and momentum management, gimbal motion, and internal instrument disturbances. To minimize the impact of these disturbances, the baseline design includes an Earth Pointed Platform (EPP), a stiff optical bench to which the two nadir pointed instruments are collocated together with the Guidance Navigation & Control (GN&C) star trackers and Inertial Measurement Units (IMUs). The EPP is passively isolated from the spacecraft bus with Honeywell D-Strut isolators providing attenuation for frequencies above approximately 5 Hz in all six degrees-of-freedom. A change in Reaction Wheel Assembly (RWA) vendors occurred very late in the program. To reduce the risk of RWA disturbances impacting performance, a secondary passive isolation system manufactured by Moog CSA Engineering was incorporated under each of the six 160 Nms RWAs, tuned to provide attenuation at frequencies above approximately 50 Hz. Integrated wheel and isolator testing was performed on a Kistler table at NASA Goddard Space Flight Center. High fidelity simulations were conducted to evaluate jitter performance for four topologies: 1) hard mounted no isolation, 2) EPP isolation only, 2) RWA isolation only, and 4) dual isolation. Simulation results demonstrate excellent performance relative to the pointing stability requirements, with dual isolated Line of Sight (LOS) jitter less than 1 micron rad.

  18. Bacillus pumilus SAFR-032 isolate

    NASA Technical Reports Server (NTRS)

    Venkateswaran, Kasthuri J. (Inventor)

    2007-01-01

    The present invention relates to discovery and isolation of a biologically pure culture of a Bacillus pumilus SAFR-032 isolate with UV sterilization resistant properties. This novel strain has been characterized on the basis of phenotypic traits, 16S rDNA sequence analysis and DNA-DNA hybridization. According to the results of these analyses, this strain belongs to the genus Bacillus. The GenBank accession number for the 16S rDNA sequence of the Bacillus pumilus SAFR-032 isolate is AY167879.

  19. A microgravity vibration isolation rig

    NASA Technical Reports Server (NTRS)

    Banerjee, Bibhuti B.; Knospe, Carl R.; Allaire, Paul E.

    1992-01-01

    It is well known that the spacecraft environment deviates from a state of zero gravity due to various random as well as repetitive sources. Science experiments that require a microgravity environment must therefore be isolated from these disturbances. Active control of noncontact magnetic actuators enables such isolation. A one degree of freedom test rig has been constructed to demonstrate the isolation capability achievable using magnetic actuators. A cylindrical mass on noncontacting electromagnetic supports simulates a microgravity experiment on board an orbiter. Disturbances generated by an electrodynamic shaker are transmitted to the mass via dashpots representing umbilicals. A compact Lorentz actuator has been designed to provide attenuation of this disturbance.

  20. The radiologically isolated syndrome.

    PubMed

    Lebrun, C

    2015-10-01

    Even prior to the introduction of criteria defining the radiologically isolated syndrome (RIS), longitudinal clinical data from individuals with incidentally identified T2 lesions suggestive of multiple sclerosis (MS) were described. Healthy individuals who do not exhibit signs of neurological dysfunction may have a brain MRI performed for a reason other than suspicion of MS that reveals unexpected anomalies highly suggestive of demyelinating plaques given their size, location, and morphology. These healthy subjects lack a history or symptomatology suggestive of MS and fulfill formal criteria for RIS, a recently described MS subtype that shares the phenotype of at-risk individuals for future demyelinating events. A formal description of RIS was first introduced in 2009 by Okuda et al., and defines a cohort of individuals who are at risk for future demyelinating events. European or North American observational studies have found that up to 30-45% of patients presenting with RIS will present with neurological symptoms, either acute or progressive. The median time to clinical conversion differs between studies. It was 2.3 years for a series of French patients and 5.4 years for an American cohort. Most patients who developed clinical symptoms had prior radiological progression. The presence of asymptomatic lesions in the cervical cord indicated an increased risk of progression, either to relapsing or to progressive MS. The consortium studying the epidemiology of RIS worldwide (RISC) presented their first retrospective cohort last year. Data were available for 451 RIS subjects (F: 354 [78.5%]). The mean age at RIS diagnosis was 37.2 years with a mean clinical follow-up time of 4.4 years. The observed 5-year conversion rate to the first clinical event was 34%. Of the converters within this time period, 9.6% fulfilled criteria for primary progressive MS. In the multivariate model, age, sex (male), and lesions within the cervical or thoracic spinal cord were identified as