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Sample records for italo mancini alla

  1. Italo Svevo and the first psychoanalytic novel.

    PubMed

    Esman, A

    2001-12-01

    The first fictional work that used psychoanalysis as a central plot device was La Coscienza di Zeno (Confessions of Zeno), published in 1923 by Ettore Schmitz, a Triestino Jewish businessman who wrote under the pseudonym of 'Italo Svevo'. This paper describes Svevo's background, his relations with such important literary figures as James Joyce and with such central figures in Italian psychoanalysis as Dr Edoardo Weiss. It seeks to demonstrate to the Anglophone reader the particular psychoanalytic elements in the novel and to relate them to Svevo's personal experience (including his indirect contacts with Freud) and to the intellectual currents of the period in a city which had, until the aftermath of the First World War, been a crossroads of European culture. PMID:11802692

  2. Preparation of Al-La Master Alloy by Thermite Reaction in NaF-NaCl-KCl Molten Salt

    NASA Astrophysics Data System (ADS)

    Jang, Poknam; Li, Hyonmo; Kim, Wenjae; Wang, Zhaowen; Liu, Fengguo

    2015-05-01

    A NaF-NaCl-KCl ternary system containing La2O3 was investigated for the preparation of Al-La master alloy by the thermite reaction method. The solubility of La2O3 in NaF-NaCl-KCl molten salt was determined by the method of isothermal solution saturation. Inductively coupled plasma-optical emission spectroscopy and x-ray diffraction (XRD) analyses were used to consider the content of La2O3 in molten salt and the supernatant composition of molten salt after dissolution of La2O3, respectively. The results showed that the content of NaF had a positive influence on the solubility of La2O3 in NaF-NaCl-KCl molten salts, and the solubility of La2O3 could reach 8.71 wt.% in molten salts of 50 wt.%NaF-50 wt.% (44 wt.%NaCl + 56 wt.%KCl). The XRD pattern of cooling molten salt indicated the formation of LaOF in molten salt, which was probably obtained by the reaction between NaF and La2O3. The kinetic study showed that the thermite reaction was in accord with a first-order reaction model. The main influence factors on La content in the Al-La master alloy product, including molten salt composition, amount of Al, concentration of La2O3, stirring, reduction time and temperature, were investigated by single-factor experimentation. The content of La in the Al-La master alloy could be reached to 10.1 wt.%.

  3. Quantification of character-impacting compounds in Ocimum basilicum and 'Pesto alla Genovese' with selected ion flow tube mass spectrometry.

    PubMed

    Amadei, Gianluca; Ross, Brian M

    2012-02-15

    Basil (Ocimum basilicum) is an important flavourant plant which constitutes the major ingredient of the pasta sauce 'Pesto alla Genovese'. The characteristic smell of basil stems mainly from a handful of terpenoids (methyl cinnamate, eucalyptol, linalool and estragole), the concentration of which varies according to basil cultivars. The simple and rapid analysis of the terpenoid constituents of basil would be useful as a means to optimise harvesting times and to act as a quality control process for basil-containing foodstuffs. Classical analytical techniques such as gas chromatography/mass spectrometry (GC/MS) are, however, slow, technically demanding and therefore less suitable for routine analysis. A new chemical ionisation technique which allows real-time quantification of traces gases, Selected Ion Flow Tube Mass Spectrometry (SIFT-MS), was therefore utilised to determine its usefulness for the assay of terpenoid concentrations in basil and pesto sauce headspace. Trace gas analysis was performed using the NO(+) precursor ion which minimised interference from other compounds. Character-impacting compound concentration was measured in basil headspace with good reproducibility and statistically significant differences were observed between cultivars. Quantification of linalool in pesto sauce headspace proved more difficult due to the presence of interfering compounds. This was resolved by careful selection of reaction product ions which allowed us to detect differences between various commercial brands of pesto. We conclude that SIFT-MS may be a valid tool for the fast and reproducible analysis of flavourant terpenoids in basil and basil-derived foodstuffs. PMID:22223305

  4. Technical Experimentation in Ship Design during the Last Decades of the Serenissima: Gerolamo Maria Balbi's Galea alla Ponentina.

    PubMed

    Campana, Lilia

    2016-01-01

    In 1744, the Venetian sea captain Gerolamo Maria Balbi (1693-1761) presented the Senate with a project to build a galea alla ponentina ("galley of Western design") that would join the Venetian fleet based in Corfu. The Senate approved Balbi's project hoping that the galley of new design would restore Venice's maritime reputation after the losses of the war against the Ottomans in 1718. The construction of the galley by the Venetian shipwright Giovan Battista Fausto lasted more than two years and was sent to Corfu in 1746. However, the newly built galley proved to be unseaworthy due to its faulty design and was sent back to Venice where it lay abandoned in the Arsenal until its dismissal in 1753. This article discusses Balbi's galley, which offers a unique glimpse into the technical experimentation in ship design in the Arsenal during the last decades of the Republic of Venice. PMID:26971731

  5. VizieR Online Data Catalog: Multi-band light curve of WASP-36 (Mancini+, 2016)

    NASA Astrophysics Data System (ADS)

    Mancini, L.; Kemmer, J.; Southworth, J.; Bott, K.; Molliere, P.; Ciceri, S.; Chen, G.; Henning, T.

    2016-05-01

    17 light curves of five transits of the extrasolar planetary system WASP-36, observed between 2012 and 2015, are presented. Four of the transits were observed simultaneously in the SDSS griz passbands using the seven-beam GROND imager on the MPG 2.2-m telescope. A fifth was observed in Cousins R with the CAHA 1.23-m telescope. (2 data files).

  6. VizieR Online Data Catalog: Light curves of WASP-67 transit events (Mancini+, 2014)

    NASA Astrophysics Data System (ADS)

    Mancini, L.; Southworth, J.; Ciceri, S.; Calchi Novati, S.; Dominik, M.; Henning, T.; Jorgensen, U. G.; Korhonen, H.; Nikolov, N.; Alsubai, K. A.; Bozza, V.; Bramich, D. M.; D'Ago, G.; Figuera Jaimes, R.; Galianni, P.; Gu, S.-H.; Harpose, K.; Hinse, T.; Hundertmark, M.; Juncher, D.; Kains, N.; Popovas, A.; Rabus, M.; Rahvar, S.; Skottfelt, J.; Snodgrass, C.; Street, R.; Surdej, J.; Tsapras, Y.; Vilela, C.; Wang, X.-B.; Wertz, O.

    2014-07-01

    5 light curves of two transits of the extrasolar planetary system WASP-67, observed on 2012 June 4 and 2013 June 22, are presented. Four of the datasets were obtained using the MPG 2.2-m telescope, GROND camera and filters similar to Sloan g', r', i', z', at the ESO Observatory in La Silla (Chile). Another data set was obtained using the 1.54-m Danish telescope, DFOSC camera and Bessel-R filter at the ESO Observatory in La Silla (Chile). (5 data files).

  7. VizieR Online Data Catalog: Light curves of WASP-80 transit events (Mancini+, 2014)

    NASA Astrophysics Data System (ADS)

    Mancini, L.; Southworth, J.; Ciceri, S.; Dominik, M.; Henning, T.; Jorgensen, U. G.; Lanza, A. F.; Rabus, M.; Snodgrass, C.; Vilela, C.; Alsubai, K. A.; Bozza, V.; Bramich, D. M.; Calchi Novati, S.; D'Ago, G.; Figuera Jaimes, R.; Galianni, P.; Gu, S.-H.; Harpose, K.; Hinse, T.; Hundertmark, M.; Juncher, D.; Kains, N.; Korhonen, H.; Popovas, A.; Rahvar, S.; Skottfelt, J.; Street, R.; Surdej, J.; Tsapras, Y.; Wang, X.-B.; Wertz, O.

    2014-01-01

    8 light curves of one transit of the extrasolar planetary system WASP-80, observed on 2013 June 16, are presented. Seven of the datasets were obtained using the MPG/ESO 2.2-m telescope, GROND camera and filters similar to Sloan g', r', i', z', and J, H, K at the ESO Observatory in La Silla (Chile). Another data set was obtained using the 1.54-m Danish telescope, DFOSC camera and Bessel-i filter at La Silla (Chile). (8 data files).

  8. Exercises for mind and body: Giulio Mancini, collecting, and the beholding of landscape painting in the seventeenth century.

    PubMed

    Gage, Frances

    2008-01-01

    This article explores the intellectual foundations for the development of princely art collections, and of Italian picture galleries in particular, as spaces for combined physical and mental exercise and recreation. This study then establishes the relationship between the therapeutic function of picture galleries and the manner in which landscape paintings produced for princely collectors at this moment in Italy embodied ideals of both exercise and repose. PMID:19235286

  9. Una ricerca sul bilinguismo precoce italo-inglese (Research on Early Italian-English Bilingualism).

    ERIC Educational Resources Information Center

    Taeschner, Traute; And Others

    1978-01-01

    The purpose of this study was to attempt to verify the theory of Taeschner and Volterra (1976) that bilingual children pass through three distinct phases while becoming perfectly bilingual. The 12 subjects were English-Italian bilingual children between the ages of 1.6 and 4.6. (CFM)

  10. VizieR Online Data Catalog: HAT-P-36 and WASP-11/HAT-P-10 light curves (Mancini+, 2015)

    NASA Astrophysics Data System (ADS)

    Mancini, L.; Esposito, M.; Covino, E.; Raia, G.; Southworth, J.; Tregloan-Reed, J.; Biazzo, K.; Bonomo, A.; Desidera, S.; Lanza, A. F.; Maciejewski, G.; Poretti, E.; Sozzetti, A.; Borsa, F.; Bruni, I.; Ciceri, S.; Claudi, R.; Cosentino, R.; Gratton, R.; Martinez Fiorenzano, A. F.; Lodato, G.; Lorenzi, V.; Marzari, F.; Murabito, S.; Affer, L.; Bignamini, A.; Bedin, L. R.; Boccato, C.; Damasso, M.; Henning, T.; Maggio, A.; Micela, G.; Molinari, E.; Pagano, I.; Piotto, G.; Rainer, M.; Scandariato, G.; Smareglia, R.; Zanmar Sanchez; R.

    2015-06-01

    3 light curves of three transit events of the extrasolar planet HAT-P-36b and 3 light curves of two transit events of the extrasolar planet WASP-11b/HAT-P-10b. Three of the datasets were obtained using the Zeiss 1.23-m telescope (filter: Cousins I) at the Observatory of Calar Alto (Spain), two with the Cassini 1.52-m telescope (filter: Gunn r) at the Astronomical Observatory of Bologna in Loiano (Italy), and one with the IAC 80-cm telescope (filter: Cousins R) at the Teide Observatory on the island of Tenerife (Spain). (6 data files).

  11. Aqui y Alla en California. (Here and There in California).

    ERIC Educational Resources Information Center

    Galarza, Ernesto

    One in the series "Coleccion Mini-Libros" (Mini-Book Collection) written in Spanish as an enrichment tool for the Spanish speaker, the booklet is a compilation of photographs accompanied by brief descriptions of various points of beauty and interest throughout the State of California. Among the points of interest described are La Sierra Nevada,…

  12. Fotometria col filtro LPR alla nova V5668 SGR

    NASA Astrophysics Data System (ADS)

    Sigismondi, Costantino

    2016-09-01

    The nova SGR 2015 no. 2 or V5668 SGR was visually observed with the LPR filter to evaluate the OIII emission. The contributions of B, V, R and Visual components to the LPR magnitude are modeled and compared with the observations in scotopic vision.

  13. La Cometa 67P Churyumov-Gerasimenko el il contributo degli astrofili italiani alla missione ROSETTA

    NASA Astrophysics Data System (ADS)

    Milani, Giannantonio

    2004-08-01

    Comet 67P Churyumov-Gerasimenko, the new target of the ROSETTA spacecraft, was oberved during the 2002/2003 apparition, displacing an unusual tail. The tail was compatible with a neck-line structure and this implies a high nuclear activity far before perihelion. Images and data from the current and previous apparitions show that the comet reaches the maximum brightening after the perihelion passage (Af[rho] = 200-250 cm).

  14. I termini di Cassini e Laplace della rifrazione atmosferica misurati alla Meridiana Clementina

    NASA Astrophysics Data System (ADS)

    Sigismondi, Costantino

    2016-05-01

    The measures of the atmospheric refraction terms of Cassini and Laplace are made at the Clementine Meridian Line of S. Maria degli Angeli in Rome by comparing the observed positions of the center of the Sun with the ones calculated without atmosphere. Three linear systems with the data of 21 Dec 2015; 18 Jan and 6 Feb 2016 give the refraction terms of tan(z) and tan3(z).

  15. Aqui y Alla: Exploring Our Lives through Poetry--Here and There

    ERIC Educational Resources Information Center

    Schlessman, Elizabeth

    2010-01-01

    The bilingual poetry and stories of Salvadoran writer Jorge Argueta have been an invaluable resource in this author's classroom. She has used poems from "Talking with Mother Earth" for homework and class analysis during a study of ecosystems, the story "Xochitl and the Flowers" to lead into persuasive writing, and "Bean Soup" to teach…

  16. "Tanto Necesitamos De Aqui Como Necesitamos De Alla": "Leer Juntas" among Mexican Transnational Mothers and Daughters

    ERIC Educational Resources Information Center

    de la Piedra, Maria Teresa

    2011-01-01

    This paper presents part of the results of a qualitative study about literacy practices of Mexican transnational mothers, who live in and frequently cross the border between two countries (the United States and Mexico). Drawing on sociocultural approaches to literacy and literature on transnationalism, I analyze one practice: "leer juntas"…

  17. Dall'italo-austrliano all'italiano: apprendmento linguistico fra gli scolari della seconda generazione (From Italian-Australian to Italian: Language Acquisition among the Students of the Second Generation).

    ERIC Educational Resources Information Center

    Rubino, Antonia

    1989-01-01

    Discusses the results of research to determine the success of the efforts currently being made in schools to teach pure Italian to the second generation of Italians in Australia in order to replace Italian Australian, a mixture of Italian dialects, Italian, and English. 33 references. (CFM)

  18. Crop water use measurement using a weighing lysimeter at the Dayr Alla Research Station in the Jordan Valley, Jordan

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Since 2003, a regional project funded by USDA-ARS-OIRP has focused on improving irrigation scheduling in Jordan, Palestine and Israel. The Middle Eastern Regional Irrigation Management Information Systems (MERMIS) project involves cooperators from Palestine, Jordan, Israel and the United States, all...

  19. Il contributo di G. Braga alla Sociologia del linguaggio (The Contributions of G. Braga to the Sociology of Language).

    ERIC Educational Resources Information Center

    Tessarolo, Marisella

    1989-01-01

    Discusses Braga's contribution to the study of the sociology of language. Braga developed a dynamic interdisciplinary model of verbal communication based on theories of sociology and linguistics and stressed the importance of language in the acculturation of an individual and in the determination of that individual's status in society. (CFM)

  20. You and Beyond. Culture and Social Organization Booklet 2. Teacher's Edition=Tu y mas alla. Cultura y organizacion social libro 2. Manual para El Maestro.

    ERIC Educational Resources Information Center

    California State Univ., Los Angeles. National Dissemination and Assessment Center.

    The booklet is part of a grade 10-12 social studies series produced for bilingual education. The series consists of six major thematic modules, with four to five booklets in each. The interdisciplinary modules are based on major ideas and designed to help students understand some major human problems and make sound, responsive decisions to improve…

  1. From Here to There. Economic Organization Booklet 2. Teacher's Edition=De aqui a alla. Organizacion economica libro 2. Manual para El Maestro.

    ERIC Educational Resources Information Center

    California State Univ., Los Angeles. National Dissemination and Assessment Center.

    The booklet is part of a grade 10-12 social studies series produced for bilingual education. The series consists of six major thematic modules, with four to five booklets in each. The interdisciplinary modules are based on major ideas and designed to help students understand some major human problems and make sound, responsive decisions to improve…

  2. Aqui y Alla (Here and There) Information-Based Learning Corridors between Tennessee and Puerto Rico: The Five Golden Rules in Intercultural Education

    ERIC Educational Resources Information Center

    Mehra, Bharat; Allard, Suzie; Qayyum, M. Asim; Barclay-McLaughlin, Gina

    2008-01-01

    This article proposes five information-based Golden Rules in intercultural education that represent a holistic approach to creating learning corridors across geographically dispersed academic communities. The Golden Rules are generated through qualitative analysis, grounded theory application, reflective practice, and critical research to…

  3. Bisogni linguistici dei discenti di italiano alla scuola di lingua e cultura italiana per stranieri di Siena (Linguistic Needs of Students of Italian at the School of Italian Language and Culture for Foreigners of Siena).

    ERIC Educational Resources Information Center

    Maggini, Massimo; Parigi, Valerio

    1986-01-01

    Presents the results of a questionnaire administered to students of Italian at the School for Foreigners of Siena to determine the following: (1) student characteristics; (2) student motivations for studying Italian; (3) student interests; (4) student linguistic needs; and (5) student evaluation of the program. (CFM)

  4. The first winter solstice observed at the meridian line of Santa Maria degli Angeli in Rome. (Italian Title: Il primo solstizio d'inverno alla meridiana di S. Maria degli Angeli in Roma)

    NASA Astrophysics Data System (ADS)

    Sigismondi, C.

    2014-09-01

    The great meridian line in the Basilica of Santa Maria degli Angeli in Rome was built in 1701/1702 with the scope to measure the Obliquity of the Earth's orbit in the following eight centuries, upon the will of pope Clement XI. During the winter solstice of 1701 the first measurements of the obliquity have been realized by Francesco Bianchini, the astronomer who designed the meridian line, upgrading the similar instrument realized by Giandomenico Cassini in San Petronio, Bononia. In this paper the accuracy of the data observed by Francesco Bianchini is discussed and compared with up-to-date ephemerides. The modern situation of this historical instrument is also presented.

  5. The Institute for the Study of Non-Model Organisms and other fantasies.

    PubMed

    Sullivan, William

    2015-02-01

    In his classic novel Invisible Cities, Italo Calvino describes a series of fantastic imagined cities that fulfill core human needs that remain unmet in ordinary cities. In light of the recent founding of a number of high-profile biomedical institutes, Calvino's descriptions encourage us to consider the unmet needs of the biomedical community and imagine unorthodox institutes designed to fulfill these needs. PMID:25633358

  6. The Institute for the Study of Non–Model Organisms and other fantasies

    PubMed Central

    Sullivan, William

    2015-01-01

    In his classic novel Invisible Cities, Italo Calvino describes a series of fantastic imagined cities that fulfill core human needs that remain unmet in ordinary cities. In light of the recent founding of a number of high-profile biomedical institutes, Calvino's descriptions encourage us to consider the unmet needs of the biomedical community and imagine unorthodox institutes designed to fulfill these needs. PMID:25633358

  7. Anthropology: Focus Upon Ethnic Studies.

    ERIC Educational Resources Information Center

    New York State Education Dept., Albany. Bureau of General Education Curriculum Development.

    This course syllabus is designed to serve as the basis for a one-semester, 12th grade anthropology course or a one-year, 12th grade ethnic studies course. As such it can be used as the culminating course in a kindergarten-grade 12 sequence. The ethnic studies component is based on data collected by an Italo-American Curriculum Studies Project and…

  8. [Indirect hemagglutination inhibition reactions as a method of titrating immune serums. V. Application of the reaction to the quantitative determination of immunoglobulins A, M and G in human blood sera].

    PubMed

    Konikova, R E; Semenova, B N; Noskov, F S; Shakhanina, K L; Malkina, L A

    1975-01-01

    The authors present the results of using the indirect hemagglutination inhibition test (IHIT) for quantitative determination of A, M and G immunoglobulins in the blood sera of humans in comparison with the method of radial immunodiffusion in agar (RID) after Mancini. The results of IHIT were no less precise and reproducible than those of RID. The significance of the correlation coefficient of grades after Spirman constituted greater than 99.9% for both tests. On this basis a conclusion was made that, having a number of advantages over RID, IHIT could be recommended for quantitative titration of immunoglobulins of various classes. PMID:804778

  9. Upper bounds on quantum uncertainty products and complexity measures

    SciTech Connect

    Guerrero, Angel; Sanchez-Moreno, Pablo; Dehesa, Jesus S.

    2011-10-15

    The position-momentum Shannon and Renyi uncertainty products of general quantum systems are shown to be bounded not only from below (through the known uncertainty relations), but also from above in terms of the Heisenberg-Kennard product . Moreover, the Cramer-Rao, Fisher-Shannon, and Lopez-Ruiz, Mancini, and Calbet shape measures of complexity (whose lower bounds have been recently found) are also bounded from above. The improvement of these bounds for systems subject to spherically symmetric potentials is also explicitly given. Finally, applications to hydrogenic and oscillator-like systems are done.

  10. Upper bounds on quantum uncertainty products and complexity measures

    NASA Astrophysics Data System (ADS)

    Guerrero, Ángel; Sánchez-Moreno, Pablo; Dehesa, Jesús S.

    2011-10-01

    The position-momentum Shannon and Rényi uncertainty products of general quantum systems are shown to be bounded not only from below (through the known uncertainty relations), but also from above in terms of the Heisenberg-Kennard product . Moreover, the Cramér-Rao, Fisher-Shannon, and López-Ruiz, Mancini, and Calbet shape measures of complexity (whose lower bounds have been recently found) are also bounded from above. The improvement of these bounds for systems subject to spherically symmetric potentials is also explicitly given. Finally, applications to hydrogenic and oscillator-like systems are done.

  11. Trichodorus elefjohnsoni n. sp. (Nemata: Trichodoridae) from Undisturbed Appalachian Forest

    PubMed Central

    Bernard, E. C.

    1992-01-01

    A new species of Trichodoridae, Trichodorus elefjohnsoni, is described from undisturbed regions of Great Smoky Mountains National Park, United States. It resembles T. orientalis De Waele &Hashim, 1984, T. persicus De Waele &Sturhan, 1987, and T. taylori De Waele, Mancini, Roca, ' Lamberti, 1982 in arrangement of ventromedian cervical papillae and posterior preanal supplements, but differs by combinations of the following characteristics: body length 516-731 μm; spicule length 33-50 μm, spicules densely striated, constricted medially; vaginal sclerotizations ovate; one pair of lateral body pores near vulva. PMID:19283205

  12. It's Not So Easy to Make Resilience Go Away: Commentary on Infurna and Luthar (2016).

    PubMed

    Galatzer-Levy, Isaac R; Bonanno, George A

    2016-03-01

    A large number of studies have identified trajectories of adjustment following acute and aversive life events. In these studies, a stable trajectory of positive health or resilience is almost always the modal outcome (Bonanno, 2004; Bonanno et al., 2011). Infurna and Luthar (2016, this issue) reported that they replicated findings from two early studies in which trajectories of subjective well-being were identified before and after divorce, widowhood, and unemployment (Galatzer-Levy, Bonanno, & Mancini, 2010; Mancini, Bonanno, & Clark, 2011) and then reanalyzed these data in such a way to conclude a decrease in the prevalence of resilience. In this commentary, we discuss three serious flaws in Infurna and Luthar's claims. First, they did not actually replicate our original analyses. They used different data, time points, and parameters. Second, the model specifications in their reanalyses were not optimal because they increased variance, reduced variability in response to the stressor, and had lower entropy, indicating that their models more poorly captured unique patterns of response. Third, their reanalyses were theoretically uninformative as they minimized both group differences and overall responses to the stressor event and thus failed to identify widely acknowledged populations, such as chronic stress reactivity. PMID:26993273

  13. WindWaveFloat

    SciTech Connect

    Weinstein, Alla

    2011-11-01

    Presentation from the 2011 Water Peer Review includes in which principal investigator Alla Weinstein discusses project progress in development of a floating offshore wind structure - the WindFloat - and incorporation therin of a Spherical Wave Energy Device.

  14. A Career in Manuscripts: Genres and Purposes of a Physician’s Writing in Rome, 1600–1630*

    PubMed Central

    De Renzi, Silvia

    2011-01-01

    Following the stellar career of papal physician Giulio Mancini, the article brings into focus learned doctors’ uses of, and relationships with, manu- scripts. Manuscripts were the main outcome of their practice — as letters of consultation to patients and colleagues, as consilia of various kinds, including for use in courts of law, and also in the form of key professional tools such as casebooks. Clues found in Mancini’s rich paper-trail shed light on material aspects of his professional writing and on the role that circulating knowledge in manuscript had in creating and sustaining medical networks. The article also argues that even in a domain as shaped by print as early modern medicine, physicians’ use of this medium should not be taken for granted; especially in courtly settings, scribal, as opposed to print, publishing provided them with an effective means of building the social relationships on which their careers depended. PMID:22298938

  15. Topological phases of fermionic ladders with periodic magnetic fields

    NASA Astrophysics Data System (ADS)

    Sun, Gaoyong

    2016-02-01

    In recent experiments bosonic [Atala et al., Nat. Phys. 10, 588 (2014), 10.1038/nphys2998; Stuhl et al., Science 349, 1514 (2015), 10.1126/science.aaa8515] as well as fermionic ladders [Mancini et al. Science 349, 1510 (2015), 10.1126/science.aaa8736] with a uniform flux were studied and different interesting many-body states were observed. Motivated by these experiments, we extend the uniform synthetic magnetic field to a periodic case and show that a commensurate synthetic magnetic field offers an alternative scheme to realize topological phases in many-body systems of ultracold Fermi gases in ladderlike optical lattices. Using the exact diagonalization, we numerically determine the topological band structure, edge states, nonzero Chern numbers, Hofstadter-butterfly-like spectrum, and a complete phase diagram of noninteracting fermionic ladders.

  16. Complexity and white-dwarf structure

    NASA Astrophysics Data System (ADS)

    Sañudo, J.; Pacheco, A. F.

    2009-02-01

    From the low-mass non-relativistic case to the extreme relativistic limit, the density profile of a white dwarf is used to evaluate the C complexity measure [R. López-Ruiz, H.L. Mancini, X. Calbet, Phys. Lett. A 209 (1995) 321]. Similarly to the recently reported atomic case where, by averaging shell effects, complexity grows with the atomic number [C.P. Panos, K.Ch. Chatzisavvas, Ch.C. Moustakidis, E.G. Kyrkou, Phys. Lett. A 363 (2007) 78; A. Borgoo, F. De Proft, P. Geerlings, K.D. Sen, Chem. Phys. Lett. 444 (2007) 186; J. Sañudo, R. López-Ruiz, Int. Rev. Phys. 2 (2008) 223], here complexity grows as a function of the star mass reaching a maximum finite value in the Chandrasekhar limit.

  17. Entropy and complexity analysis of hydrogenic Rydberg atoms

    SciTech Connect

    Lopez-Rosa, S.; Toranzo, I. V.; Dehesa, J. S.; Sanchez-Moreno, P.

    2013-05-15

    The internal disorder of hydrogenic Rydberg atoms as contained in their position and momentum probability densities is examined by means of the following information-theoretic spreading quantities: the radial and logarithmic expectation values, the Shannon entropy, and the Fisher information. As well, the complexity measures of Cramer-Rao, Fisher-Shannon, and Lopez Ruiz-Mancini-Calvet types are investigated in both reciprocal spaces. The leading term of these quantities is rigorously calculated by use of the asymptotic properties of the concomitant entropic functionals of the Laguerre and Gegenbauer orthogonal polynomials which control the wavefunctions of the Rydberg states in both position and momentum spaces. The associated generalized Heisenberg-like, logarithmic and entropic uncertainty relations are also given. Finally, application to linear (l= 0), circular (l=n- 1), and quasicircular (l=n- 2) states is explicitly done.

  18. A comparison of LMC and SDL complexity measures on binomial distributions

    NASA Astrophysics Data System (ADS)

    Piqueira, José Roberto C.

    2016-02-01

    The concept of complexity has been widely discussed in the last forty years, with a lot of thinking contributions coming from all areas of the human knowledge, including Philosophy, Linguistics, History, Biology, Physics, Chemistry and many others, with mathematicians trying to give a rigorous view of it. In this sense, thermodynamics meets information theory and, by using the entropy definition, López-Ruiz, Mancini and Calbet proposed a definition for complexity that is referred as LMC measure. Shiner, Davison and Landsberg, by slightly changing the LMC definition, proposed the SDL measure and the both, LMC and SDL, are satisfactory to measure complexity for a lot of problems. Here, SDL and LMC measures are applied to the case of a binomial probability distribution, trying to clarify how the length of the data set implies complexity and how the success probability of the repeated trials determines how complex the whole set is.

  19. Some New Reflections on Mr. Palomar

    NASA Astrophysics Data System (ADS)

    Bertolami, O.

    2009-08-01

    The character Mr. Palomar, the alter-ego of the Italian author Italo Calvino, appeared for the first time in 1975 on the pages of the ``Il Corriere della Sera'', and then more or less regularly till its debut as a book in 1983. Through illuminating thoughts and reflections based on observations, for instance, of sea waves, Mr. Palomar discovers that they induce a peaceful and inspirational state of mind that prevents coronary and mental illnesses, and also holds the key to capturing the complexity of the world reducing it into its most elementary mechanisms. In this contribution I will survey some of Mr. Palomar's thoughts while he observes the sky and speculate on others that he might have explored if he shared our contemporary knowledge of the cosmos. I will also discuss the thoughts of other authors on how, cosmological thinking affects the human condition.

  20. SCDC Spanish Curricula Units. Fine Arts Strand, Unit 9, Grade 3, Supplement & Ditto Packet.

    ERIC Educational Resources Information Center

    Spanish Curricula Development Center, Miami Beach, FL.

    The supplement and ditto packet to the fine arts strand of unit nine for third graders contains illustrations, ditto masters, and four songbooks to help the teacher carry out the fine arts activities of this unit. Materials for both group activities and seatwork are included. Kit 33 uses the songbook "Canciones de Aqui y de Alla" and studies the…

  1. First optical observations of artificial Earth's satellites

    NASA Astrophysics Data System (ADS)

    Rykhlova, L. V.

    2008-08-01

    A review of the first optical observations of the artificial satellites in the USSR as well as in former communist countries (DDR, Romania,Poland) is given. The role by Alla G. Masevich, I.D. Zhongolovich and Yu.V. Batrakov is underlined in the organization of observations.

  2. Three-dimensional Simulations of Thermonuclear Detonation with α-Network: Numerical Method and Preliminary Results

    NASA Astrophysics Data System (ADS)

    Khokhlov, A.; Domínguez, I.; Bacon, C.; Clifford, B.; Baron, E.; Hoeflich, P.; Krisciunas, K.; Suntzeff, N.; Wang, L.

    2012-07-01

    We describe a new astrophysical version of a cell-based adaptive mesh refinement code ALLA for reactive flow fluid dynamic simulations, including a new implementation of α-network nuclear kinetics, and present preliminary results of first three-dimensional simulations of incomplete carbon-oxygen detonation in Type Ia Supernovae.

  3. Careers and people

    NASA Astrophysics Data System (ADS)

    2016-07-01

    Medical physicist Alla Reznik's work on next-generation positron emission tomography (PET) devices – which recently won her a Leadership Award from the Ontario Research and Innovation Optical Network (ORION) – developed out of more than a decade of research into the fundamental properties of wide band-gap semiconductors.

  4. Multi-view areal-density maps of compressed shells in OMEGA direct-drive implosions extracted from MMI data

    NASA Astrophysics Data System (ADS)

    Johns, Heather; Joshi, Tirtha; Mayes, Daniel; Durmaz, Tunay; Mancini, Roberto; Tommasini, Riccardo; Delettrez, Jacques; Regan, Sean; Nagayama, Taisuke

    2012-10-01

    In a series of implosion experiments performed at the OMEGA laser facility, spherical plastic shells doped with an embedded titanium tracer-layer and filled with deuterium gas were driven with high- and low-adiabat laser pulse shapes. The titanium emergent intensity distribution was recorded with a streaked spectrometer and three identical gated, multi-monochromatic x-ray imaging instruments (MMI) that observed the implosion along three quasi-orthogonal lines-of-sight. The data shows spectral signatures due to absorption K-shell line transitions in titanium L-shell ions that are backlit by the continuum radiation from the hot core. To interpret these observations, the MMI spectrally-resolved image data were processed to obtain narrow-band images and spatially-resolved spectra based on the titanium spectral features.footnotetextT. Nagayama, R.C. Mancini, R. Florido, et al, J. App. Phys. 109, 093303 (2011) Areal-density maps were extracted using two independent methods based on narrow-band images and spatially-resolved spectra. The areal-density maps reveal the 3D structure and state of the compressed shell through the collapse of the implosion and the performance differences between high- and low-adiabat implosions.

  5. Theoretical polarization-dependent X-ray spectra of Be-like Fe calculated for different electron beam densities

    NASA Astrophysics Data System (ADS)

    Shlyaptseva, Alla; Mancini, Roberto

    1998-05-01

    We study theoretically the polarization properties of X-ray spectra of Be-like Fe ions excited through resonant capture by an electron beam with different electron densities. Our previous work in this area was related to the study of polarization of dielectronic satellite lines of Fe ions excited by a low-density electron beam. (A.S. Shlyaptseva, R.C. Mancini, P. Neill, P. Beiersdorfer, J.R. Crespo López-Urrutia, and K. Widmann, Phys. Rev. A, 57), 888 (1998) Here we extend our work to the case of higher-density electron beams. As the density of the electron beam increases, new channels of electron capture appear. Thus the atomic and polarization characteristics of the satellite lines change. Moreover, additional X-ray satellite lines will appear. Using the density matrix formalism, we calculate the polarization characteristics and polarization-dependent spectra of dielectronic satellite lines of Be-like Fe produced at different energies and densities of the electron beam. We compare the results of the present work with our previous ones for low-density electron beams. These results are relevant to the identification of X-ray polarization-dependent spectral features and for X-ray line polarization spectroscopy.

  6. Correlation Energy of A Model Problem

    NASA Astrophysics Data System (ADS)

    Campuzano, Mauricio; Fessatidis, Vassilios; Mancini, Jay D.; Bowen, Samuel P.

    2006-03-01

    The search for new analytic methods of calculating details of the energy spectrum of strongly interacting systems has long been the vocation of both theoretical chemists and physicists. In particular, the accurate calculation of both the ground-state and correlation energies are important in settling issues relating to the exact nature of the ground-state and low-lying excited states. Furthermore there exist a number of physically relevant systems that cannot be treated by perturbation theory or in which other approximation schemes yield completely erroneous results. Exact diagonalization studies are well known to suffer from size effects, while the neglection of correlations in fluctuations in mean-field theories, although calculationally tractable, leave much to be desired. Here we wish to apply a recently developed Generalized Moments Expansion (GMX) [1] to the problem of N coupled one dimensional harmonic oscillators given by the Hamiltonian: H=12∑j=1^N( -d^2dxj^2+2circ % xj^2) +g^2∑ij^Nxij. Comparisons are then made with other methods such as a Lanczos tridiagonalization scheme as well as a Canonical Sequence Method approach. 1] V. Fessatidis, J.D. Mancini, R. Murawski and S.P. Bowen, Phys. Lett. A.

  7. Medical competence, anatomy and the polity in seventeenth-century Rome

    PubMed Central

    De Renzi, Silvia

    2007-01-01

    At the centre of this article are two physicians active in Rome between 1600 and 1630 who combined medical practice with broader involvement in the dynamic cultural, economic and political scene of the centre of the Catholic world. The city's distinctive and very influential social landscape magnified issues of career-building and allows us to recapture physicians’ different strategies of self-fashioning at a time of major social and religious reorganization. At one level, reconstructing Johannes Faber and Giulio Mancini's medical education, arrival in Rome and overlapping but different career trajectories contributes to research on physicians’ identity in early modern Italian states. Most remarkable are their access to different segments of Roman society, including a dynamic art market, and their diplomatic and political role, claimed as well as real. But following these physicians from hospitals to courts, including that of the Pope, and from tribunals to the university and analysing the wide range of their writing – from medico-legal consilia to political essays and reports of anatomical investigations – also enriches our view of medical practice, which included, but went beyond, the bedside. Furthermore, their activities demand that we reassess the complex place of anatomical investigations in a courtly society, and start recovering the fundamental role played by hospitals – those quintessential Catholic institutions – as sites of routine dissections for both medical teaching and research. (pp. 551–567) PMID:21949463

  8. Isolation of C4-binding protein from guinea pig plasma and demonstration of its function as a control protein of the classical complement pathway C3 convertase.

    PubMed

    Burge, J; Nicholson-Weller, A; Austen, K F

    1981-01-01

    A decay-accelerating factor of the classical complement pathway C3 convertase, C4b,2a, has been purified to homogeneity from guinea pig plasma by a 5-step procedure that includes 5% polyethyleneglycol-4000 (PEG-4000) precipitation, Sepharose 6B gel filtration, heparin-Sepharose chromatography, DE-52 anion exchange chromatography, and Sepharose-C4gp affinity chromatography. The protein elicited a monospecific antiserum in a rabbit and was found with the Mancini technique in both normal and C4-deficient guinea pig plasma at a concentration of 60 microgram/ml. The purified protein gave a single stained band of 550,000 m.w. on SDS-PAGE under nonreducing conditions and a single band of 72,000 m.w. with reduction and alkylation. On the basis of its m.w. and subunit structure, ability to bind to a C4 affinity column, and ability to regulate the classical C system by accelerating the decay of the classical C3 convertase this protein represents the guinea pig analog of the human C4-binding protein. PMID:6778916

  9. Bacterial Porphyrin Extraction and Quantification by LC/MS/MS Analysis

    PubMed Central

    Mancini, Stefano; Imlay, James A.

    2016-01-01

    Heme is an iron-containing porphyrin which acts as a prosthetic group in several enzymes involved in disparate functions, such as respiration and H2O2-scavenging. Escherichia coli is able to produce heme endogenously since it contains all the enzymes involved in the nine-step biosynthesis pathway, which in absence of stress and in iron-replete media proceeds unabated. However, we recently showed that two steps are affected by H2O2 stress (Mancini and Imlay, 2015). To compensate, two enzymes, namely the ferrochelatase (HemH) and an isozyme of coproporphyrinogen III oxidase (HemF), are activated by the H2O2-responsive regulator OxyR. Genetic mutations that block either adaptation cause the intracellular accumulation of protoporphyrin IX and coproporphyrinogen III, the substrates of HemH and HemF, respectively. We here describe a method used to extract and quantify protoporphyrin IX and coproporphyrin III, the product of the spontaneous oxidation of coproporphyrinogen III.

  10. Code Validation Utilizing Spectral Data Analysis of ICF Implosion Experiments on OMEGA

    NASA Astrophysics Data System (ADS)

    Gunderson, Mark; Haynes, Donald, Jr.; Delamater, Norman; Regan, Sean

    2003-10-01

    Time-resolved spectral data from recent ICF implosion experiments of plastic microballoons containing deuterium fuel doped with argon is proving quite useful in checking the corresponding 1D and 2D simulation results from the multi-dimensional hydrocode RAGE [1]. Comparisons with experimental density and temperature determined by fitting theoretical argon line shapes generated by MERL [2] to experimental data show that the simulated density and temperature in the fuel are too large unless some seed for mixing is incorporated. We use a nonuniform drive as a seed for mix. The need for mix is further supported through simulations using the 1D Lagrangian code HYADES (no mix) that give neutron yields an order of magnitude larger than that seen in experiment. This work was performed under NLUF grant DE-FG03-01SF22224 and DOE contract No. W-7405-ENG-36. [1] Gittings, M.L., SAIC's adaptive grid Eulerian hydrocode, DNA Numerical Methods Symposium, Apr 1992. [2] Mancini, R.C., Kilcrease, D.P., Woltz, L.A., and Hooper Jr., C.F., Comput. Phy. Commun. 63, 314-322 (1991).

  11. Cultural, social and personal ways of experiencing love – an analysis of the perception of subjectivity

    PubMed Central

    Gori, Claudia

    2011-01-01

    Summary This article is based on analysis of 4 couple’s personal and public documents, in order to integrate personal choices, values and ideas with cultural representations and social attitudes. Moreover, being based on Italian sources from the nineteenth century, the study offers an historical insight on the Italian nation-building process and its political and social foundations. This study is based on archival and printed primary sources from: Gianna Maffei and Ercole Trotti Mosti (Museo Centrale del Risorgimento – Roma – MCRR); Augusto Pierantoni and Grazia Mancini (Museo Centrale del Risorgimento – Roma); Luigi Majno and Ersilia Bronzini (Archivio Unione Femminile Nazionale – Milano); Angiolo Orvieto and Laura Cantoni (Archivio Contemporaneo Bonsanti del Gabinetto Vieuesseux – Firenze – ACGV). This study reflects on love as a political and moral issue, by linking the personal sphere of subjectivity to the public dimension of the political community. An extensive understanding of the role played by the perception and the expression of sentiments can be considered as the central issue of this analysis. PMID:22037756

  12. Il problema del litio.

    NASA Astrophysics Data System (ADS)

    D'Antona, F.

    1995-03-01

    Contents: 1. Introduzione. 2. La nucleosintesi del Big Bang. 3. Il litio nelle stelle di popolazione II. 4. I modelli stellari standard. 5. Il litio negli ammassi aperti. 6. Meccanismi di distruzione "non standard". 7. I modelli non-standard applicati alla popolazione II. 8. L'evoluzione Galattica del litio. 9. Quali stelle producono litio? 10. Il litio come elemento chiave per dare un nome agli oggetti stellari più minuscoli. 11. Conclusioni.

  13. Lo Gnomone Clementino Astronomia Meridiana in Basilica

    NASA Astrophysics Data System (ADS)

    Sigismondi, Costantino

    2014-05-01

    Costruito per chiara volontà del papa 70 anni dopo il caso Galileo, lo Gnomone Clementino è un grande telescopio solare che non fa uso di lenti a 92 anni dall’invenzione del cannocchiale. Queste due caratteristiche basterebbero da sole a giustificare l’interesse verso questo strumento. L’astronomia meridiana è alla base dell’astrometria e dell’astrofisica moderna. Lo Gnomone Clementino sta oggi all’astronomia, come il veliero “Amerigo Vespucci” sta alla Marina Italiana. E’ possibile svolgere ogni genere di osservazione e studio su questo strumento, e dal 2002 vi tengo lezioni teorico-pratiche del corso di Storia dell’Astronomia e La Terra nel Sistema Solare della Sapienza, Università di Roma, Facoltà di Lettere e Filosofia. Questo testo aggiunge alcuni tasselli alla ricerca storica sulla meridiana, appoggiandosi, com’è naturale, sulle spalle di giganti che mi hanno preceduto in questi studi. In particolare la misura dell’azimut della meridiana, ed il suo inquadramento tra gli strumenti simili ed alcuni studi di astrometria sui dati del 1701-1703 di Bianchini, che sono apparsi fin’ora soltanto su riviste specializzate ed in Inglese vengono qui proposti in Italiano e semplificati, per valorizzare sempre più questa straordinaria opera d’arte e di scienza.

  14. Clinical phenotype, muscle MRI and muscle pathology of LGMD1F.

    PubMed

    Peterle, Enrico; Fanin, Marina; Semplicini, Claudio; Padilla, Juan Jesus Vilchez; Nigro, Vincenzo; Angelini, Corrado

    2013-08-01

    Of the seven autosomal dominant genetically distinct forms of LGMD so far described, in only four the causative gene has been identified (LGMD1A-1D). We describe clinical, histopathological and muscle MRI features of a large Italo-Spanish kindred with LGMD1F presenting proximal-limb and axial muscle weakness. We obtained complete clinical data and graded the progression of the disease in 29 patients. Muscle MRI was performed in seven patients. Three muscle biopsies from two patients were investigated. Patients with age at onset in the early teens, had a more severe phenotype with a rapid disease course; adult onset patients presented a slow course. Muscle MRI showed prominent atrophy of lower limb muscles, involving especially the vastus lateralis. Widening the patients population resulted in the identification of previously unreported features, including dysphagia, arachnodactyly and respiratory insufficiency. Muscle biopsies showed diffuse fibre atrophy, which evolved with time, chronic myopathic changes, basophilic cytoplasmic areas, autophagosomes and accumulation of myofibrillar and cytoskeletal proteins. The LGMD1F is characterized by a selective involvement of limb muscles with respiratory impairment in advanced stages, and by different degrees of clinical progression. Novel clinical features emerged from the investigation of additional patients. PMID:23632945

  15. Isla Hispaniola: A trans-boundary flood risk mitigation plan

    NASA Astrophysics Data System (ADS)

    Brandimarte, Luigia; Brath, Armando; Castellarin, Attilio; Baldassarre, Giuliano Di

    It is sadly known that over the past decades Isla Hispaniola (Haiti and the Dominican Republic) has been exposed to the devastating passage of several hurricanes and tropical storms. Territories that are economically weak and extremely poor in terms of natural resources have been shaken by severe flood events that caused the loss of thousands of human lives, displacement of people and damage to the environment. On May 24th 2004, the flooding of the trans-boundary river Soliette killed over 1000 Haitian and Dominican people, wiping out villages and leaving behind desolation and poverty. After this catastrophic flood event, the General Direction for Development and Cooperation of the Italian Department of Foreign Affairs funded through the Istituto Italo-Latino Americano (IILA, www.iila.org) an international cooperation initiative (ICI), coordinated and directed by the University of Bologna. The ICI involved Haitian and Dominican institutions and was twofold: (a) institutional capacity building on flood risk management and mitigation measures and policies; (b) hydrological and hydraulic analysis of the May 2004 flood event aimed at formulating a suitable and affordable flood risk mitigation plan, consisting of structural and non-structural measures.

  16. Ultrastructural changes in LGMD1F.

    PubMed

    Cenacchi, Giovanna; Peterle, Enrico; Fanin, Marina; Papa, Valentina; Salaroli, Roberta; Angelini, Corrado

    2013-06-01

    A large Italo-Spanish kindred with autosomal-dominant inheritance has been reported with proximal limb and axial muscle weakness. Clinical, histological and genetic features have been described. A limb girdle muscular dystrophy 1F (LGMD1F) disease locus at chromosome 7q32.1-32.2 has been previously identified. We report a muscle pathological study of two patients (mother and daughter) from this family. Muscle morphologic findings showed increased fiber size variability, fiber atrophy, and acid-phosphatase-positive vacuoles. Immunofluorescence against desmin, myotilin, p62 and LC3 showed accumulation of myofibrils, ubiquitin binding protein aggregates and autophagosomes. The ultrastructural study confirmed autophagosomal vacuoles. Many alterations of myofibrillar component were detected, such as prominent disarray, rod-like structures with granular aspect, and occasionally, cytoplasmic bodies. Our ultrastructural data and muscle pathological features are peculiar to LGMD1F and support the hypothesis that the genetic defect leads to a myopathy phenotype associated with disarrangement of the cytoskeletal network. PMID:23279333

  17. Panic attacks and possession by djinns: lessons from ethnopsychiatry

    PubMed Central

    Bragazzi, Nicola Luigi; Del Puente, Giovanni

    2012-01-01

    This clinical case report shows how important it is for a psychiatrist to have a knowledge of the cultural and religious context of the patient, in order to understand fully his or her complaints. Culture and religion, in fact, are not neutral, but convey symbols, meanings, and myths that should be properly explored to shed light on the patient’s inner world. Patient D was a 19-year-old Muslim Italo-Tunisian girl, who consulted a psychiatrist for anxiety and panic attacks, and reported being possessed by djinns (ie, “evil creatures”, as described in the Qur’an). A culturally informed interview was carried out, together with administration of psychometric scales, including the Symptom Checklist-90 Revised and Psychological Measure of Islamic Religiousness. Based on her scores and the results of this multidimensional assessment, patient D was treated with transcultural psychotherapy and fluoxetine. After a year of follow-up, she reported no further episodes of panic disorder. For proper assessment and treatment, a combined anthropological, sociological, and psychopathological approach was necessary. PMID:23293545

  18. Analysis of spontaneous MEG activity in mild cognitive impairment and Alzheimer's disease using spectral entropies and statistical complexity measures

    NASA Astrophysics Data System (ADS)

    Bruña, Ricardo; Poza, Jesús; Gómez, Carlos; García, María; Fernández, Alberto; Hornero, Roberto

    2012-06-01

    Alzheimer's disease (AD) is the most common cause of dementia. Over the last few years, a considerable effort has been devoted to exploring new biomarkers. Nevertheless, a better understanding of brain dynamics is still required to optimize therapeutic strategies. In this regard, the characterization of mild cognitive impairment (MCI) is crucial, due to the high conversion rate from MCI to AD. However, only a few studies have focused on the analysis of magnetoencephalographic (MEG) rhythms to characterize AD and MCI. In this study, we assess the ability of several parameters derived from information theory to describe spontaneous MEG activity from 36 AD patients, 18 MCI subjects and 26 controls. Three entropies (Shannon, Tsallis and Rényi entropies), one disequilibrium measure (based on Euclidean distance ED) and three statistical complexities (based on Lopez Ruiz-Mancini-Calbet complexity LMC) were used to estimate the irregularity and statistical complexity of MEG activity. Statistically significant differences between AD patients and controls were obtained with all parameters (p < 0.01). In addition, statistically significant differences between MCI subjects and controls were achieved by ED and LMC (p < 0.05). In order to assess the diagnostic ability of the parameters, a linear discriminant analysis with a leave-one-out cross-validation procedure was applied. The accuracies reached 83.9% and 65.9% to discriminate AD and MCI subjects from controls, respectively. Our findings suggest that MCI subjects exhibit an intermediate pattern of abnormalities between normal aging and AD. Furthermore, the proposed parameters provide a new description of brain dynamics in AD and MCI.

  19. Efficacy of Bilevel-auto Treatment in Patients with Obstructive Sleep Apnea Not Responsive to or Intolerant of Continuous Positive Airway Pressure Ventilation

    PubMed Central

    Carlucci, Annalisa; Ceriana, Piero; Mancini, Marco; Cirio, Serena; Pierucci, Paola; D'Artavilla Lupo, Nadia; Gadaleta, Felice; Morrone, Elisa; Fanfulla, Francesco

    2015-01-01

    Background: Ventilation with continuous positive airway pressure (CPAP) is the gold standard therapy for obstructive sleep apnea (OSA). However, it was recently suggested that a novel mode of ventilation, Bilevel-auto, could be equally effective in treating patients unable to tolerate CPAP. The aim of this study was to investigate the ability of Bilevel-auto to treat OSA patients whose nocturnal ventilatory disturbances are not completely corrected by CPAP. Methods: We enrolled 66 consecutive OSA patients, not responsive to (group A) or intolerant of (group B) CPAP treatment, after a full night of manual CPAP titration in a laboratory. Full polysomnography data and daytime sleepiness score were compared for each group in the three different conditions: basal, during CPAP, and during Bilevel-auto. Results: The apnea-hypopnea index decreased significantly during CPAP in both groups; however, in the group A, there was a further significant improvement during Bilevel-auto. The same trend was observed for oxygenation indices, while the distribution and the efficiency of sleep did not differ following the switch from CPAP to Bilevel-auto. Conclusions: This study confirmed the role of Bilevel-auto as an effective therapeutic alternative to CPAP in patients intolerant of this latter mode of ventilation. Moreover, extending the use of Bilevel-auto to those OSA patients not responsive to CPAP, we showed a significantly better correction of nocturnal respiratory disturbances. Citation: Carlucci A, Ceriana P, Mancini M, Cirio S, Pierucci P, D'Artavilla Lupo N, Gadaleta F, Morrone E, Fanfulla F. Efficacy of Bilevel-auto treatment in patients with obstructive sleep apnea not responsive to or intolerant of continuous positive airway pressure ventilation. J Clin Sleep Med 2015;11(9):981–985. PMID:25902825

  20. Toxicity models of pulsed copper exposure to Pimephales promelas and Daphnia magna.

    PubMed

    Butcher, Jonathan; Diamond, Jerry; Bearr, Jonathan; Latimer, Henry; Klaine, T Stephen J; Hoang, Tham; Bowersox, Marcus

    2006-09-01

    Semiempirical models are useful for interpreting the response of aquatic organisms to toxicants as a function of exposure concentration and duration. Most applications predict cumulative mortality at the end of the test for constant exposure concentrations. Summary measures, such as the median lethal concentration, are then estimated as a function of concentration. Real-world exposures are not constant. Effects may depend on pulse timing, and cumulative analysis based only on integrated exposure concentration is not sufficient to interpret results. We undertook a series of pulsed-exposure experiments using standard toxicological protocols and interpreted the results (mortality, biomass, and reproduction) using a dynamic generalization of a Mancini/Breck--type model that includes two compartments, one for internal concentration as a function of exposure and one for site-of-action concentration or accumulated damage as a function of the internal dose. At exposure concentrations near the effects level, the model explained approximately 50% of the variability in the observed time history of survival, 43% of the change in biomass, and 83% of the variability in net reproduction. Unexplained variability may result from differences in organism susceptibility, amplified by the effects of small sample sizes in standard tests. The results suggest that response is sensitive to prior conditions and that constant-exposure experiments can underestimate the risk from intermittent exposures to the same concentration. For pulsed exposures, neither the average nor the maximum concentration alone is an adequate index of risk, which depends on both the magnitude, duration, and timing of exposure pulses. Better understanding about the impacts of pulsed exposures will require use of experimental protocols with significantly greater numbers of replicates. PMID:16986811

  1. Analysis of spontaneous MEG activity in mild cognitive impairment and Alzheimer's disease using spectral entropies and statistical complexity measures.

    PubMed

    Bruña, Ricardo; Poza, Jesús; Gómez, Carlos; García, María; Fernández, Alberto; Hornero, Roberto

    2012-06-01

    Alzheimer's disease (AD) is the most common cause of dementia. Over the last few years, a considerable effort has been devoted to exploring new biomarkers. Nevertheless, a better understanding of brain dynamics is still required to optimize therapeutic strategies. In this regard, the characterization of mild cognitive impairment (MCI) is crucial, due to the high conversion rate from MCI to AD. However, only a few studies have focused on the analysis of magnetoencephalographic (MEG) rhythms to characterize AD and MCI. In this study, we assess the ability of several parameters derived from information theory to describe spontaneous MEG activity from 36 AD patients, 18 MCI subjects and 26 controls. Three entropies (Shannon, Tsallis and Rényi entropies), one disequilibrium measure (based on Euclidean distance ED) and three statistical complexities (based on Lopez Ruiz-Mancini-Calbet complexity LMC) were used to estimate the irregularity and statistical complexity of MEG activity. Statistically significant differences between AD patients and controls were obtained with all parameters (p < 0.01). In addition, statistically significant differences between MCI subjects and controls were achieved by ED and LMC (p < 0.05). In order to assess the diagnostic ability of the parameters, a linear discriminant analysis with a leave-one-out cross-validation procedure was applied. The accuracies reached 83.9% and 65.9% to discriminate AD and MCI subjects from controls, respectively. Our findings suggest that MCI subjects exhibit an intermediate pattern of abnormalities between normal aging and AD. Furthermore, the proposed parameters provide a new description of brain dynamics in AD and MCI. PMID:22571870

  2. Orthographic learning in dyslexic Spanish children.

    PubMed

    Suárez-Coalla, Paz; Ramos, Sara; Alvarez-Cañizo, Marta; Cuetos, Fernando

    2014-07-01

    Reading fluency is one of the basic processes of learning to read. Children begin to develop fluency when they are able to form orthographic representations of words, which provide direct, smooth, and fast reading. Dyslexic children of transparent orthographic systems are mainly characterized by poor reading fluency (Cuetos & Suárez-Coalla 2009; Spinelli, De Luca, Di Filippo, Mancini, Martelli, & Zoccolotti, 2005; Wimmer, 1993). Therefore, the main problem for these children could be the difficulty in developing orthographic representations of the words they read. The aim of this study was to test the ability of dyslexic Spanish-speaking children (whose native language is Spanish) to develop orthographic representations and determine if the context helps them. For this, two experiments were conducted with a group of 100 children, 7-12 years of age. The groups were comprised of 20 dyslexics, 40 chronological age-matched controls and 40 reading level-matched controls. In the first experiment, eight unfamiliar words (four short and four long) were presented six times within the context of a story. In the second experiment, eight pseudowords were presented on a computer and the children had to read them aloud. In both experiments, the reading and articulation times of experimental and control stimuli were compared, before and after the training. Children without dyslexia showed a decrease of the influence of length of word on reading speed, indicating a lexical reading, while for dyslexic children, the influence of length remained unchanged. These results appeared when the stimuli were presented in the context of a story as well as when presented in isolation. In short, our results describe that dyslexic children of transparent orthographic systems have problems in developing orthographic representations of words. PMID:25056668

  3. Experimental investigation of opacity models for stellar interiors, inertial fusion, and high energy density plasmas

    NASA Astrophysics Data System (ADS)

    Bailey, James

    2008-11-01

    Theoretical opacities are required for calculating energy transport in plasmas. In particular, understanding stellar interiors, inertial fusion, and Z-pinches depends on the opacities of mid-atomic-number elements in the 150-300 eV temperature range. These models are complex and experimental validation is crucial. For example, solar models presently disagree with helioseismology and one possible explanation is inadequate opacities. Testing these opacities requires a uniform plasma at temperatures high enough to produce the ion charge states that exist in the sun. Typical opacity experiments heat a sample using x-rays and measure the spectrally resolved transmission with a backlight. The difficulty grows as the temperature increases because the heating x-ray source must supply more energy and the backlighter source must be bright enough to overwhelm the plasma self emission. These problems were overcome using the dynamic hohlraum x-ray source at Sandia's Z facility to measure the transmission of a mixed Mg-Fe plasma heated above 150 eV. This capability will also advance opacity science for other high energy density plasmas. This tutorial describes opacity experiment challenges including accurate transmission measurements, plasma diagnostics, and quantitative model comparisons. The solar interior serves as a focal problem and Z facility experiments are used to illustrate the techniques. **In collaboration with C. Iglesias (LLNL), R. Mancini (U. Nevada), J.MacFarlane, I. Golovkin and P. Wang (Prism), C. Blancard, Ph. Cosse, G. Faussurier, F. Gilleron, and J.C. Pain (CEA), J. Abdallah Jr. (LANL), and G.A. Rochau and P.W. Lake (Sandia). ++Sandia is a multiprogram laboratory operated by Sandia Corporation, a Lockheed Martin Company, for the United States Department of Energy under contract DE-AC04-94AL85000.

  4. Imagineering the astronomical revolution - Essay review

    NASA Astrophysics Data System (ADS)

    Jardine, Nicholas.

    2006-11-01

    Concerning following Books: (I) Transmitting knowledge - words, images, and instruments in early modern Europe. Kusukawa and Maclean (eds.), OUP, Oxford, 2006; (II) Widmung, Welterklärung und Wissenschaftslegitimierung: Titelbilder und ihre Funktionen in der wissenschaftlichen Revolution. Remmert, Harrassowitz, Wiesbaden, 2005; (III) The power of images in early modern science. Lefevre, Renn and Schoepflin (eds.), Birkhäuser, Basel, 2003; (IV) Immagini per conoscere - dal Rinascimento alla rivoluzione scientifica. Meroi and Pogliano (eds.), Olschki, Florenz, 2001; (V) Erkenntnis Erfindung Konstruktion - Studien zur Bildgeschichte von Naturwissenschaften und Technik vom 16. bis zum 19. Jahrhundert. Holländer (ed.), Mann, Berlin, 2000.

  5. The acoustic design of the Centro Nacional de las Artes in Mexico City

    NASA Astrophysics Data System (ADS)

    Cooper, Rusell

    2002-11-01

    In this paper the acoustic design of the separate buildings housing the school of music, school of drama, and school of dance that opened in 1996 will be described. Spaces that JHA designed included practice rooms, studios, rehearsal rooms, black box, and concert hall. Details of room acoustic treatments, sound isolation measures, and venturi air flow will be illustrated. An overview of the entire project will also include the 500 seat multipurpose theater (with variable absorption systems) and the Alla Magna. Differences between the American and Mexican styles of consulting, importing of materials, installation, and commissioning will also be discussed.

  6. Polar asymmetry of La{sub (1−δ)}Al{sub (1+δ)}O{sub 3}/SrTiO{sub 3} heterostructures probed by optical second harmonic generation

    SciTech Connect

    Rubano, Andrea; De Luca, Gabriele; Marrucci, Lorenzo; Paparo, Domenico; Schubert, Jürgen; Wang, Zhe; Zhu, Shaobo; Schlom, Darrell G.

    2015-09-07

    By combining transport measurements and optical second harmonic generation, we have investigated heterostructures formed between crystalline thin films of LaAlO{sub 3}, with varying stoichiometry and TiO{sub 2}-terminated SrTiO{sub 3}(001) substrates. Optical second harmonic generation directly probes the polarity of these heterostructures, thus complementing the transport data. The stoichiometry and the growth temperature are found to be critical parameters for controlling both the interfacial conductivity and the heterostructure polarity. In agreement with the previous work, all of the samples display an insulator-to-metal transition in the Al-reach region, with the conductivity first increasing and then saturating at the highest Al/La ratios. The second harmonic signal also increases as a function of the Al/La ratio, but, at the highest growth temperature, it does not saturate. This unusual behavior is consistent with the formation of an ordered structure of defect dipoles in the LaAlO{sub 3} film caused by the off-centering of excess Al atoms in agreement with the theory.

  7. Different reactivity of monoclonal antibodies against common acute lymphoblastic leukaemia antigen (CD10).

    PubMed Central

    Haralambidou, S; Melo, J V; Catovsky, D

    1987-01-01

    The reactivity of five monoclonal antibodies J5, OKB-cALLA, Nu-N1, Nu-N2 and VIL-A1 against the common acute lymphoblastic leukaemia (common-ALL) antigen (glycoprotein 100, CD10); was investigated by indirect immunofluorescence in cell suspensions, and by immunoperoxidase in cytocentrifuge slides of ALL, chronic B cell lymphoproliferative disorders, and plasma cell dyscrasias. The five monoclonal antibodies gave similar positive results with both techniques only in samples of ALL. J5 was positive in variable degrees by immunofluorescence in the majority of B cell disorders examined but this was not confirmed by immunoperoxidase. OKB-cALLA reacted in a similar way to J5 in both techniques, although with a lower percentage of cells by immunofluorescence. Nu-N1, Nu-N2, and VIL-A1 were mainly negative when tested by both immunofluorescence and immunoperoxidase in B cell disorders other than ALL and therefore seemed to be more specific for the diagnosis of common-ALL. PMID:2953763

  8. Introduzione Nuove tecnologie in urologia.

    PubMed

    Bianchi, Giampaolo

    2011-03-30

    Negli ultimi anni sono state introdotte in urologia nuove tecniche chirurgiche alcune già applicabili nella pratica clinica, altre ancora in corso di sperimentazione. Quella che ha trovato attualmente applicazione è la LESS (Laparo Endoscopic Single-site Surgery); essa riguarda tutte le metodiche che utilizzano una sola porta (multiaccesso) per eseguire interventi laparoscopici. I vantaggi apparenti di questa metodica rispetto alla laparoscopia tradizionale sono soltanto un dimostrato miglior risultato estetico. Mancano studi prospettici randomizzati. NOTES (Natural Orifices Transluminal Endoscopic Surgery) È una metodica ancor più nuova che sfrutta gli orifizi naturali (bocca, retto, vagina, vescica per accedere alla cavità addominale. Rispetto alla LESS questa tecnica utilizza prevalentemente i gastroscopi e lo strumentario dei gastoenterologi per eseguire interventi demolitivi. In urologia l'impiego di questa metodica è puramente sperimentale, comunque piccoli passi sono stati fatti nel migliorare lo strumentario. I chirurghi stanno consolidando questa metodica sull'uomo riguardo alla colecistectomia, ma i risultati sono scarsi, discordanti sulla via d'accesso e limitati a case reports. Oggi i risultati più incoraggianti li ha descritti Estevao Lima, un ingegnoso portoghese che utilizzando una tecnica NOTES di terza generazione (accesso combinato trans-vescicale e trans-gastrico) è riuscito ad eseguire una serie di nefrectomie sul maiale. Tanto si sa e si è speculato riguardo al robot da Vinci®, che oggi la prostatectomia senza di lui non è più competitiva. Moltissimi sono i centri che lo hanno, molti quelli che lo usano, tanti quelli che hanno risultati migliori rispetto alla tecnica laparoscopica classica. Ancora ad oggi però non esistono studi prospettici randomizzati che dimostrino la sua superiorità; inoltre una spina nel fianco sono i costi. Un ulteriore sviluppo futuro di da Vinci® forse potrebbe vedersi nell'assistere le nuove tecniche

  9. An overview on the history of pedology and soil mapping in Italy

    NASA Astrophysics Data System (ADS)

    Calzolari, C.

    2012-04-01

    In Italy, the word pedology (pedologia) was introduced in a text book as synonym of soil science for the first time in 1904 by Vinassa de Regny. In the literature, the term cohabitates with the words agrology (agrologia), agro-geology (agro-geologia), agricultural geognostic (geognostica agraria), geopedology (geo-pedologia) used in different historical moments by differently rooted soil scientists. When early pedologists started with systematic studies of soils, their characteristics and geography, they were strongly influenced by their cultural background, mainly geology and agro-chemistry. Along the time, the soil concept evolved, as did the concept of pedology, and this is somehow witnessed by the use of different Italian words with reference to soil: suolo, terreno, terra. Differently from agro-chemists, early pedologists based the soil study on the field description of soil profile. This was firstly based on the vertical differentiation between humus rich layers and "inactive" layers and later on, as long as the discipline evolved, on the presence of genetic horizons. The first complete soil map of Italy is dated 1928. Its Author, the geologist De Angelis d'Ossat, was the president of the organising committee of the 1924 International Soil Conference of Rome, where the International Society of Soil Science was founded. The map was based on the geological map of Italy, drafted in scale 1:1,000,000 after the creation of the Kingdom of Italy in 1861. The internal disputes within the Geological Society, together with the scarce interest of most of geologists for soil, did not facilitate the birth of a central soil survey. Soil mapping was mainly conducted by universities and research institutes, and we had to wait until 1953 for a new soil map (scale 1:3,125,000) at national level to be realised by Paolo Principi, based on literature data. In 1966 a new 1:1,000,000 soil map of Italy was eventually published by a national committee, led by Fiorenzo Mancini. This

  10. Stratospheric aerosol optical depth: comparison of global model results with SAGE II and HALOE observations in the visible and near-, far-infrared channels

    NASA Astrophysics Data System (ADS)

    Pitari, Giovanni; de Luca, Natalia; Mancini, Eva; Bekki, Slimane; Mills, Michael; Timmreck, Claudia; Weisenstein, Debra

    2010-05-01

    Stratospheric aerosol optical depth: comparison of global model results with SAGE II and HALOE observations in the visible and near-, far-infrared channels G. Pitari (1), N. De Luca (1), E. Mancini (1), S. Bekki (2), M. Mills (3), C. Timmreck (4), D. Weisenstein (5) (1) Università degli Studi de L'Aquila, L'Aquila, Italy (2) Université Pierre e Marie Curie, Paris, France (3) University of Colorado, Boulder, CO, USA (4) Max-Planck Institut für Meteorologie, Hamburg, Germany (5) Atmospheric and Environmental Research, Inc., Lexington, MA, USA Stratospheric aerosols have been recognized to play an important role in the global climate system by influencing the Earth radiative balance and by providing a surface for heterogeneous chemistry. The accurate modeling of the shape and characteristics of the stratospheric aerosol layer requires the knowledge of their microphysical properties and the atmospheric distribution of their tropospheric precursor gases (SO2, OCS). The background aerosol distribution in the stratosphere may be sporadically perturbed for a time period of about five years after major explosive volcanic eruptions, that may inject in the stratosphere large amounts of SO2 and H2S. The most extensive coverage of the stratospheric aerosol distribution has been made using instruments on board of satellites (SAGE and HALOE in particular). Here we compare the distribution of stratospheric aerosols calculated by five global models with aerosol modules on-line against satellite observations. The results of two 3-D models (MPI and ULAQ) and three 2-D models (AER, LASP, UPMC) are used for this comparison, for both non-volcanic and volcanically perturbed conditions. The comparison is made in terms of aerosol extinction and optical depth: these are calculated using Mie scattering programs where the model calculated aerosol mass distribution is used as input as a function of the particle radius. The size distribution calculated in the models is the final product of

  11. Resource Assessment of the In-Place and Potentially Recoverable Deep Natural Gas Resource of the Onshore Interior Salt Basins, North Central and Northeastern Gulf of Mexico

    SciTech Connect

    Ernest A. Mancini

    2006-09-30

    -five percent of the gas is estimated to be from late cracking of oil in the source rock. Lewan (2002) concluded that much of the thermogenic gas produced in this basin is the result of cracking of oil to gas in deeply buried reservoirs. The efficiency of expulsion, migration and trapping has been estimated to range from 0.5 to 10 percent for certain basins (Schmoker, 1994: Zimmerman, 1999). The estimate of the total hydrocarbons generated for the Mississippi Interior Salt Basin is 910 billion barrels using the method of Schmoker (1994), and the estimate of the total hydrocarbons generated is 1,540 billion barrels using the Platte River software application. The estimate of gas generated for this basin is 3,130 TCF using the Platte River software application, and 4,050 TCF using the method of Schmoker (1994). Seventy-five percent of the gas is estimated to be from late cracking of oil in the source rock. Claypool and Mancini (1989) report that the conversion of oil to gas in reservoirs is a significant source of thermogenic gas in this basin. The Manila and Conecuh Subbasins are oil-prone. Although these subbasins are thermally mature for oil generation and expulsion, they are not thermally mature for secondary, non-associated gas generation and expulsion. The gas produced from the highly productive gas condensate fields (Big Escambia Creek and Flomaton fields) in these subbasins has been interpreted to be, in part, a product of the cracking of oil to gas and thermochemical reduction of evaporite sulfate in the reservoirs (Claypool and Mancini, 1989). The areas in the North Louisiana and Mississippi Interior Salt Basins with high potential for deeply buried gas reservoirs (>15,000 ft) have been identified. In the North Louisiana Salt Basin, these potential reservoirs include Upper Jurassic and Lower Cretaceous facies, especially the Smackover, Cotton Valley, Hosston, and Sligo units. The estimate of the secondary, non-associated gas generated from cracking of oil in the source

  12. The orbital record in stratigraphy

    NASA Technical Reports Server (NTRS)

    Fischer, Alfred G.

    1992-01-01

    Orbital signals are being discovered in pre-Pleistocene sediments. Due to their hierarchical nature these cycle patterns are complex, and the imprecision of geochronology generally makes the assignment of stratigraphic cycles to specific orbital cycles uncertain, but in sequences such as the limnic Newark Group under study by Olsen and pelagic Cretaceous sequence worked on by our Italo-American group the relative frequencies yield a definitive match to the Milankovitch hierarchy. Due to the multiple ways in which climate impinges on depositional systems, the orbital signals are recorded in a multiplicity of parameters, and affect different sedimentary facies in different ways. In platform carbonates, for example, the chief effect is via sea-level variations (possibly tied to fluctuating ice volume), resulting in cycles of emergence and submergence. In limnic systems it finds its most dramatic expression in alternations of lake and playa conditions. Biogenic pelagic oozes such as chalks and the limestones derived from them display variations in the carbonate supplied by planktonic organisms such as coccolithophores and foraminifera, and also record variations in the aeration of bottom waters. Whereas early studies of stratigraphic cyclicity relied mainly on bedding variations visible in the field, present studies are supplementing these with instrumental scans of geochemical, paleontological, and geophysical parameters which yield quantitative curves amenable to time-series analysis; such analysis is, however, limited by problems of distorted time-scales. My own work has been largely concentrated on pelagic systems. In these, the sensitivity of pelagic organisms to climatic-oceanic changes, combined with the sensitivity of botton life to changes in oxygen availability (commonly much more restricted in the Past than now) has left cyclic patterns related to orbital forcing. These systems are further attractive because (1) they tend to offer depositional continuity

  13. PREFACE: FLUIDOS 2010: XI Meeting on Recent Advances in the Physics of Fluids and their Applications

    NASA Astrophysics Data System (ADS)

    Bove, Italo; Cabeza, Cecilia; Martí, Arturo C.; Sarasúa, Gustavo

    2011-04-01

    anticipate enjoying another successful FLUIDOS meeting to be held in one of the main cultural centres of the continent. Italo Bove, Cecilia Cabeza, Arturo C Martí, and Gustavo SarasúaEditors

  14. Geographic variation in social acceptability of wildland fuels management in the western United States

    USGS Publications Warehouse

    Brunson, M.; Schindler, Bruce A.

    2004-01-01

    Contemporary natural resource management requires consideration of the social acceptability of management practices and conditions. Agencies wishing to measure, respond to, and influence social acceptability must understand the nuances of public perception regarding controversial issues. This study explores social acceptability judgments about one such issue: reduction of wildland fuel hazards on federal lands in the western United States. Citizens were surveyed in four locations where fire has been a significant ecological disturbance agent and public land agencies propose to reduce wildland fuel levels and wildfire hazards via prescribed burning, thinning, brush removal, and/or livestock grazing. Respondents in different locations differed in their knowledge about fire and fuel issues as well in their acceptability judgments. Differences are associated with location-specific social and environmental factors as well as individual beliefs. Results argue against using a??one-size-fits-alla?? policies or information strategies about fuels management.

  15. Scaling up ATLAS Database Release Technology for the LHC Long Run

    NASA Astrophysics Data System (ADS)

    Borodin, M.; Nevski, P.; Vaniachine, A.; ATLAS Collaboration

    2011-12-01

    To overcome scalability limitations in database access on the Grid, ATLAS introduced the Database Release technology replicating databases in files. For years Database Release technology assured scalable database access for Monte Carlo production on the Grid. Since previous CHEP, Database Release technology was used successfully in ATLAS data reprocessing on the Grid. Frozen Conditions DB snapshot guarantees reproducibility and transactional consistency isolating Grid data processing tasks from continuous conditions updates at the "live" Oracle server. Database Release technology fully satisfies the requirements of ALLAS data reprocessing and Monte Carlo production. We parallelized the Database Release build workflow to avoid linear dependency of the build time on the length of LHC data-taking period. In recent data reprocessing campaigns the build time was reduced by an order of magnitude thanks to a proven master-worker architecture used in the Google MapReduce. We describe further Database Release optimizations scaling up the technology for the LHC long run.

  16. L'eliosismologia: onde sismiche per studiare l'interno del Sole

    NASA Astrophysics Data System (ADS)

    Di Mauro, M. P.

    2014-12-01

    Negli ultimi cinquanta anni siamo stati testimoni di una straordinaria rivoluzione della conoscenza e comprensione della nostra stella grazie alla nascita dell'Eliosismologia, lo studio delle oscillazioni solari. Analogamente a ciò che accade nella Terra durante i terremoti, anche l'interno del Sole è pervaso continuamente da onde sismiche che provocano piccole oscillazioni, ovvero deformazioni della fotosfera. Le oscillazioni sono la manifestazione di diversi processi che avvengono all'interno della struttura del Sole e le frequenze sismiche dei modi osservati e misurati sulla superficie sono legate direttamente ai parametri fisici degli strati interni attraversati dalle onde sismiche. Lo studio delle oscillazioni rappresenta, quindi, l'unico metodo diretto per studiare la struttura e la dinamica interna del Sole. In questo articolo verranno illustrate le caratteristiche generali delle oscillazioni solari e verranno presentati i risultati importanti e i progressi notevoli raggiunti grazie all'Eliosismologia.

  17. Purine metabolism enzyme pattern, cytochemical characteristics and clinicopathologic features of CD10-positive childhood T-cell leukemia.

    PubMed

    Babusíková, O; Cáp, J; Hrivnáková, A; Klobusická, M; Mesárosová, A; Koníková, E

    1991-01-01

    Purine metabolism enzyme pattern, cytochemical markers and clinicopathologic features of common acute lymphoblastic leukemia antigen (cALLA; CD10)-positive, CD10-negative T acute lymphoblastic leukemia (ALL), and cALLA-positive non-T, non-B ALL (common ALL; C ALL) of children were compared. The results of immunophenotyping of blast cells in 61 children with ALL who were treated and followed during the last 7 years at the Second Pediatric Clinic in Bratislava are presented. The aim of our study was to determine the correlation of CD10 marker expression with purine enzyme activities and clinical course in ALL of children. Immunologic phenotype performed by a panel of monoclonal antibodies in indirect immunofluorescence assay revealed 3 main ALL groups: Common ALL (C ALL), T ALL and CD10+ T ALL (C + T ALL). An additional exact cytochemical marker analysis was performed in these three ALL immunologic subtypes. Two enzymes of purine metabolism, i.e. adenosine deaminase (ADA) and purine nucleosidephosphorylase (PNP) were investigated in blast cells by paper radiochromatography. Life-table analysis revealed significant prognostic differences with regard to event-free survival and overall survival in followed groups of ALL patients. Our results showed a rather high frequency of mixed (C + T) ALL phenotype. The characteristic T ALL enzyme pattern (high ADA, low PNP) was present not only in T, but also in CD10+ T ALL blast cells. The T cell marker showed to be dominant in the determination of clinical course and prognostic significance in children with ALL; children with T and CD10+ T ALL phenotype, in contrast to C ALL phenotype, experienced more frequent relapses and a shorter event-free survival. PMID:1837333

  18. Nationwide program of education for undergraduates in the field of disaster medicine: development of a core curriculum centered on blended learning and simulation tools.

    PubMed

    Ingrassia, Pier Luigi; Ragazzoni, Luca; Tengattini, Marco; Carenzo, Luca; Della Corte, Francesco

    2014-10-01

    In recent years, effective models of disaster medicine curricula for medical schools have been established. However, only a small percentage of medical schools worldwide have considered at least basic disaster medicine teaching in their study program. In Italy, disaster medicine has not yet been included in the medical school curriculum. Perceiving the lack of a specific course on disaster medicine, the Segretariato Italiano Studenti in Medicina (SISM) contacted the Centro di Ricerca Interdipartimentale in Medicina di Emergenza e dei Disastri ed Informatica applicata alla didattica e alla pratica Medica (CRIMEDIM) with a proposal for a nationwide program in this field. Seven modules (introduction to disaster medicine, prehospital disaster management, definition of triage, characteristics of hospital disaster plans, treatment of the health consequences of different disasters, psychosocial care, and presentation of past disasters) were developed using an e-learning platform and a 12-hour classroom session which involved problem-based learning (PBL) activities, table-top exercises, and a computerized simulation (Table 1). The modules were designed as a framework for a disaster medicine curriculum for undergraduates and covered the three main disciplines (clinical and psychosocial, public health, and emergency and risk management) of the core of "Disaster Health" according to the World Association for Disaster and Emergency Medicine (WADEM) international guidelines for disaster medicine education. From January 2011 through May 2013, 21 editions of the course were delivered to 21 different medical schools, and 524 students attended the course. The blended approach and the use of simulation tools were appreciated by all participants and successfully increased participants' knowledge of disaster medicine and basic competencies in performing mass-casualty triage. This manuscript reports on the designing process and the initial outcomes with respect to learners

  19. Integration of porosity, connectivity and permeability measurements to determine syn-eruptive degassing processes during a sub-plinian basaltic eruption

    NASA Astrophysics Data System (ADS)

    Jordan, Simone; Gurioli, Lucia; Colombier, Matthieu; Le Pennec, Jean-Luc; Roche, Olivier

    2015-04-01

    samples, however, show that the vesicles in each clast are fully connected to each other, while the permeability of the clasts varies by two orders (10-11-10-13m2). Textural analysis of the different vesicle networks will give better insights into the cause of this discrepancy. These interesting results indicate the importance of both connectivity and permeability measurements and textural analysis for the evaluation of the presence of a vesicle network and the potential for degassing prior to fragmentation. References: Polacci, M., Baker, D.R., La Rue, A., Mancini, L., Allard, P., 2012. Degassing behaviour of vesiculated basaltic magmas: an example from Ambrym volcano, Vanuatu Arc. J. Volcanol. Geotherm. Res., 233-234, 55-64. Rust, A.C., Cashman, K.V., 2004. Permeability of vesicular silicic magma: inertial and hysteresis effects. Earth Planet. Sci. Lett., 228, 93-107. Saar, M.O., Manga, M., 1999. Permeability-porosity relationship in vesicular basalts. Geophs. Res. Lett., 26, 111-114. Takeuchi, S., Nakashima, S., Tomiya, A., 2008. Permeability measurements of natural and experimental volcanic materials with a simple permeameter: Toward an understanding of magmatic degassing processes. J. Volcanol. Geotherm. Res., 177, 329-339.

  20. Crystallization kinetics in magmas during decompression

    NASA Astrophysics Data System (ADS)

    Arzilli, Fabio; Burton, Mike; Carroll, Michael R.

    2016-04-01

    aspect to understand magma evolution in the magma chamber and in the conduit, which in turn has strong effects on magma rheology. The onset of the crystallization process in basaltic melts during experiments was characterized by an initial nucleation event within the first hour of the experiment, which produced the largest amount of plagioclase [3]. This nucleation event, at short experimental duration, can produce a dramatic change in crystal number density and crystal fraction, triggering a significant textural evolution in only 1 h. The obtained results show that crystallization kinetics are strictly related to undercooling, time, final pressure, superheating and water content in the melt. Here we show that a small decrease in pressure could induce a dramatic increase of crystallinity in few hours, in natural systems this may affect the magma rheology and eruptive dynamics on very short time scales. References: [1] Ghiorso MS (1997) Thermodynamic models of igneous. Annu Rev Earth Planet Sci 25:221-241. [2] Arzilli F, Carroll MR (2013) Crystallization kinetics of alkali feldspars in cooling and decompression-induced crystallization experiments in trachytic melt. Contrib Mineral Petrol 166:1011-1027. [3] Arzilli F, Agostini C, Landi P, Fortunati A, Mancini L, Carroll MR (2015) Plagioclase nucleation and growth kinetics in a hydrous basaltic melt by decompression experiments. Contrib Mineral Petrol 170:55.

  1. Monitoring biodegradation of hydrocarbons by stable isotope fractionation

    NASA Astrophysics Data System (ADS)

    Dorer, Conrad; Fischer, Anko; Herrmann, Steffi; Richnow, Hans-Hermann; Vogt, Carsten

    2010-05-01

    nitrate, sulfate or ferric iron as electron acceptor or using light as energy source [3,4,5]. Significantly different lambda values were also observed for the anaerobic degradation of xylenes initiated by the BSS [5]. The different lambda values obtained for the anaerobic degradation of toluene and xylenes might be caused by slightly different reaction mechanisms of BSS isoenzymes. In comparison, lambda and/or ɛbulk values for the methyl monohydroxylation of toluene with oxygen as co-substrate were significantly different for two tested strains each containing a different toluene attacking enzyme, indicating that specific enzymes for aerobic methyl group oxidation reactions can be detected by CSIA and 2D-CSIA. Our results show that the combined carbon and hydrogen isotope fractionation approach has great potential to elucidate biodegradation pathways of monoaromatic hydrocarbons in microcosm and field studies. Current work focus on (i) 2D-CSIA of aromatic and aliphatic hydrocarbons in degradation experiments using whole cells, and (ii) 2D-CSIA of aromatic hydrocarbons in in vitro experiments using cell extracts. [1] Fischer et al. (2008) Environ. Sci. Technol. 42, 4356-4363 [2] Mancini et al. (2008) Environ. Sci. Technol. 42, 8290-8296 [3] Vogt et al. (2008) Environ. Sci. Technol. 42, 7793-7800 [4] Tobler et al. (2008) Environ. Sci. Technol. 42, 7786-7792 [5] Herrmann et al. (2009) Environ. Microbiol. Reports 1, 535-544

  2. A new eco-hydrological distributed model for the analysis of the climate change impact on water resources of Mediterranean ecosystems: the Flumendosa basin case study in Sardinia

    NASA Astrophysics Data System (ADS)

    Sarigu, Alessio; Cortis, Clorinda; Montaldo, Nicola

    2014-05-01

    In the last three decades, climate change and human activities increased desertification process in Mediterranean regions, with dramatic consequences for agriculture and water availability. For instance in the Flumendosa reservoir system in Sardinia the average annual runoff in the latter part of the 20th century was less than half the historic average rate, while the precipitation over the Flumendosa basin has decreased, but not at such a drastic rate as the discharge, suggesting a marked non-linear response of discharge to precipitation changes. With the objective of analyzing and looking for the reasons of the historical runoff decrease a new ecohydrological model is developed and tested for the main basin of the Sardinia island, the Flumendosa basin. The eco-hydrological model developed couples a distributed hydrological model and a vegetation dynamic model (VDM). The hydrological model estimates the soil water balance of each basin cell using the force-restore method and the Philips model for runoff estimate. Then it computes runoff propagation along the river network through a modified version of the Muskingum -Cunge method (Mancini et al., 2000; Montaldo et al., 2004). The VDM evaluates the changes in biomass over time from the difference between the rates of biomass production (photosynthesis) and loss (respiration and senescence), and provides LAI, which is then used by the hydrological model for evapotranspiration and rainfall interception estimates. Case study is the Flumendosa basin (Sardinia, basin area of about 1700 km2), which is characterized by a reservoir system that supplies water to the main city of Sardinia, Cagliari. Data are from 42 rain stations (1922-2008 period) over the entire basin and data of runoff are available for the same period. The model has been successfully calibrated for the 1922 - 2008 period for which rain, meteorological data and discharge data are available. We demonstrate that the hystorical strong decrease of runoff is

  3. Geological and geophysical activities at Spallanzani Science Department (Liceo Scientifico Statale "Lazzaro Spallanzani" - Tivoli, Italy)

    NASA Astrophysics Data System (ADS)

    Favale, T.; De Angelis, F.; De Filippis, L.

    2012-04-01

    The high school Liceo Scientifico "Lazzaro Spallanzani" at Tivoli (Rome) has been fully involved in the study of geological and geophysical features of the town of Tivoli and the surrounding area in the last twelve years. Objective of this activity is to promote the knowledge of the local territory from the geological point of view. Main activities: • School year 2001-2002: Setting up inside the school building of a Geological Museum focusing on "Geological Evolution of Latium, Central Italy" (in collaboration with colleagues M. Mancini, and A. Pierangeli). • March, 15, 2001: Conference of Environmental Geology. Lecturer: Prof. Raniero Massoli Novelli, L'Aquila University and Società Italiana di Geologia Ambientale. • School years 2001-2002 and 2002-2003: Earth Sciences course for students "Brittle deformation and tectonic stress in Tivoli area". • November, 2003: Conference of Geology, GIS and Remote Sensing. Lecturers: Prof. Maurizio Parotto and Dr Alessandro Cecili (Roma Tre University, Rome), and Dr Stefano Pignotti (Istituto Nazionale per la Ricerca sulla Montagna, Rome). • November, 2003, 2004 and 2005: GIS DAY, organized in collaboration with ESRI Italia. • School year 2006-2007: Earth Sciences course for students "Acque Albule basin and the Travertine of Tivoli, Latium, Central Italy" (focus on travertine formation). • School year 2010-2011: Earth Sciences course for students "Acque Albule basin and the Travertine of Tivoli. Geology, Hydrogeology and Microbiology of the basin, Latium, Central Italy" (focus on thermal springs and spa). In the period 2009-2010 a seismic station with three channels, currently working, was designed and built in our school by the science teachers Felice De Angelis and Tomaso Favale. Our seismic station (code name LTTV) is part of Italian Experimental Seismic Network (IESN) with identification code IZ (international database IRIS-ISC). The three drums are online in real time on websites http

  4. Western closure of the Corinth Rift: Stratigraphy and structure of the Lakka fault block

    NASA Astrophysics Data System (ADS)

    Palyvos, Nikos; Ford, Mary; Mancini, Marco; Esu, Daniela; Girotti, Odoardo; Urban, Brigitte

    2013-04-01

    conglomerates, lignites and mudstones (Koumaris formation). In the area of the Meganitis and Selinous rivers, the Profitis Ilias group underlies and may be partly laterally equivalent to the Early to Middle Pleistocene Middle group comprising Gilbert deltas sourced from the south. New data indicate that the Profitis Ilias group was a fluvio-lacustrine system sourced from the north. Accommodation was probably created by an, as yet, unidentified south dipping fault on the north side of or below the present Gulf. The same fluvio-lacustrine system may be traced into the Patras area, further west. The Profitis Ilias group depocentre may have been part of the NE limit of the Patras rift. The westernmost Corinth rift was therefore dominated by continental facies until late Middle Pleistocene. The Rion Straits did not open west to the Mediterranean until well after 400 Ka. Any marine influence in the earlier rift came from the east. Palyvos N., Mancini M., Sorel D., Lemeille F., Pantosti D., Julia R., Triantaphyllou M., De Martini P.M. (2010) - Geomorphological, stratigraphic and geochronologic evidence of fast Pleistocene coastal uplift in the westernmost part of the Corinth Gulf (Greece). Geological Journal, 45, 78-104.

  5. High blood pressure in older subjects with cognitive impairment.

    PubMed

    Mossello, Enrico; Simoni, David

    2016-01-01

    , probabilmente secondaria alla neurodegenerazione. L'effetto prognostico dei valori pressori in anziani con decadimento cognitivo non è stato ancora chiarito, in presenza di un possibile effetto dannoso di un trattamento antiipertensivo aggressivo in questa categoria di pazienti. Un breve screening cognitivo, associato con una semplice valutazione motoria, è raccomandato per identificare gli anziani fragili, che necessitano di un approccio più cauto alla terapia antiipertensiva. I risultati del monitoraggio della pressione arteriosa nelle 24 ore sembrano più utili della misurazione clinica per predire la prognosi degli anziani cognitivamente compromessi. Studi futuri dovrebbero identificare gli obiettivi pressori più appropriati nel trattamento di anziani con decadimento cognitivo. PMID:27374044

  6. [Modello di Management (Mo.Ma) del paziente affetto da schizofrenia: controllo della crisi, mantenimento, prevenzione delle ricadute e recovery con gli antipsicotici LAI].

    PubMed

    Brugnoli, Roberto; Rapinesi, Chiara; Kotzalidis, Georgios D; Marcellusi, Andrea; Mennini, Francesco S; De Filippis, Sergio; Carrus, Dario; Ballerini, Andrea; Francomano, Antonio; Ducci, Giuseppe; Del Casale, Antonio; Girardi, Paolo

    2016-01-01

    RIASSUNTO. La schizofrenia colpisce circa l'1% della popolazione e rappresenta un grave disturbo mentale con un notevole impatto anche sul funzionamento sociale, lavorativo e sulle attività della vita quotidiana. Le persone con schizofrenia hanno un tasso di mortalità superiore di 2-2,5 rispetto a quello della popolazione generale. La non aderenza ai farmaci antipsicotici è uno dei più importanti fattori di rischio per le ricadute e le ospedalizzazioni, sia nei pazienti con disturbo cronico sia al primo episodio, e conseguentemente contribuisce all'aumento dei costi sanitari. Gli antipsicotici atipici LAI possono migliorare l'aderenza al trattamento contribuendo a diminuire i tassi di ricaduta nei pazienti affetti da schizofrenia fin dall'esordio. Gli obiettivi primari nella gestione dei pazienti schizofrenici sono diretti, non solo alla riduzione dei sintomi nel breve termine, ma anche al mantenimento fisico e della funzionalità mentale, migliorando la qualità della vita e promuovendo il recupero del paziente. Scopo. Proporre un modello integrato, basato sulle evidenze, che fornisca un algoritmo efficace per il recupero del paziente schizofrenico e indagare l'efficacia e la sicurezza degli antipsicotici LAI nel trattamento, nel mantenimento, nella prevenzione delle ricadute e nella recovery dei pazienti affetti da schizofrenia. Metodi. Dopo un'accurata analisi di letteratura abbiamo identificato, raccolto e analizzato gli elementi qualificanti per un'ottimale gestione del paziente schizofrenico, definendo un modello di gestione e selezione delle alternative terapeutiche. Conclusioni. Il modello di gestione della schizofrenia proposto potrebbe consentire un migliore recupero funzionale del paziente grazie alla scelta di iniziare il percorso terapeutico, fin dalle prime fasi del disturbo soprattutto se in giovane età e al primo episodio, con un farmaco atipico LAI. All'interno dei farmaci antipsicotici atipici la formulazione LAI rappresenta una scelta

  7. The logic in language: How all quantifiers are alike, but each quantifier is different.

    PubMed

    Feiman, Roman; Snedeker, Jesse

    2016-06-01

    Quantifier words like each, every, all and three are among the most abstract words in language. Unlike nouns, verbs and adjectives, the meanings of quantifiers are not related to a referent out in the world. Rather, quantifiers specify what relationships hold between the sets of entities, events and properties denoted by other words. When two quantifiers are in the same clause, they create a systematic ambiguity. "Every kid climbed a tree" could mean that there was only one tree, climbed by all, or many different trees, one per climbing kid. In the present study, participants chose a picture to indicate their preferred reading of different ambiguous sentences - those containing every, as well as the other three quantifiers. In Experiment 1, we found large systematic differences in preference, depending on the quantifier word. In Experiment 2, we then manipulated the choice of a particular reading of one sentence, and tested how this affected participants' reading preference on a subsequent target sentence. We found a priming effect for all quantifiers, but only when the prime and target sentences contained the same quantifier. For example, all-a sentences prime other all-a sentences, while each-a primes each-a, but sentences with each do not prime sentences with all or vice versa. In Experiment 3, we ask whether the lack of priming across quantifiers could be due to the two sentences sharing one fewer word. We find that changing the verb between the prime and target sentence does not reduce the priming effect. In Experiment 4, we discover one case where there is priming across quantifiers - when one number (e.g. three) is in the prime, and a different one (e.g. four) is in the target. We discuss how these findings relate to linguistic theories of quantifier meaning and what they tell us about the division of labor between conceptual content and combinatorial semantics, as well as the mental representations of quantification and of the abstract logical structure of

  8. Effects of surface states, defects and dopants on the optical and magnetic properties of low-dimensional materials

    NASA Astrophysics Data System (ADS)

    Podila, Ramakrishna

    a range of magnetic properties in ZnO can result, depending on the sample preparation and annealing conditions. For example, within the same ZnO sample we have observed ferro- to para- and diamagnetic responses depending on the annealing conditions. We also explored the effects of surface states on the magnetic behavior of nanoscale ZnO through detailed calculations. In the case of grapheme, we have observed new combination modes in the range from 1650 to 2300 cm-1 in single-(SLG), bi-, few-layer and incommensurate bilayer graphene (IBLG) on silicon dioxide substrates. A peak at ˜1860 cm-1 (iTALO- ) is observed due to a combination of the in-plane transverse acoustic (iTA) and the longitudinal optical (LO) phonons. The intensity of this peak decreases with increasing number of layers and this peak is absent for bulk graphite. The overtone of the out-of-plane transverse optical (oTO) phonon at ˜1750 cm-1, also called the M band, is suppressed for both SLG and IBLG. In addition, two previously unidentified modes at ˜2200 and ˜1880 cm-1 are observed in SLG. The 2220 cm -1 (1880 cm-1) mode is tentatively assigned to the combination mode of in-plane transverse optical (iTO) and TA phonons (oTO+LO phonons) around the K point in the graphene Brillouin zone. Finally, the peak frequency of the 1880 (2220) cm-1 mode is observed to increase (decrease) linearly with increasing graphene layers. Finally, we find that the high curvature in sub-nm SWCNTs leads to (i) an unusual S-like dispersion of the G-band frequency due to perturbations caused by the strong electron-phonon coupling, (ii) an activation of diameter-selective intermediate frequency modes that are as intense as the radial breathing modes (RBMs), and (iii) a clear observation of the IR modes.

  9. Central radio galaxies in groups: cavities, bubbles and the history of AGN heating

    NASA Astrophysics Data System (ADS)

    Giacintucci, S.; Venturi, T.; Raychaudhury, S.; Vrtilek, J.

    2008-10-01

    E' noto che le regioni centrali degli ammassi e gruppi di galassie costituiscono un ambiente in cui gas caldo e plasma radioemittente proveniente dalle galassie dominanti interagiscono tra loro. In particolare, si pensa che la radioemissione dell'AGN centrale ed i suoi possibili cicli di attivita', siano strettamente legati alla presenza di cavita' e "bubbles" nel gas intergalattico. Si presentera' lo status di un progetto osservativo effettuato con il Giant Metrewave Radio Telescope (GMRT, India) su di un campione di 18 gruppi di galassie, osservati a tre frequenze radio (235 MHz, 325 MHz e 610 MHz). Lo studio della morfologia radio degli AGN centrali e la relativa analisi spettrale permettono di ottenere stime sull'eta' di questi oggetti, e sulla loro energia totale, che a loro volta sono in relazione con le proprieta' X dei gruppi stessi. Per tutti gli oggetti del campione sono disponibili osservazioni Chandra di proprieta'. Per due oggetti del campione, 4C+24.36 (al centro di AWM04) e NGC741 (al centro di RSOG17) verra' presentato uno studio dettagliato.

  10. Morphology and immunology of circulating cells in leukaemic phase of follicular lymphoma.

    PubMed Central

    Melo, J V; Robinson, D S; De Oliveira, M P; Thompson, I W; Lampert, I A; Ng, J P; Galton, D A; Catovsky, D

    1988-01-01

    Ten patients with follicular lymphoma presented with a high white cell count (45-220 x 10(9)/l) which resembled chronic lymphocytic leukaemia (CCL): all had pronounced splenomegaly and, except one, generalised lymphadenopathy. The blood lymphocytes were small with scanty cytoplasm, densely condensed nuclear chromatin, and deep clefts originating in sharp angles from the nuclear surface. CLL cells are larger, have more cytoplasm, a different pattern of chromatin condensation, and may have shallow nuclear indentations or foldings rather than clefts. The circulating follicular lymphoma cells had moderate to strong membrane immunoglobulins (SmIg), low mouse (M)-rosettes, strong reactivity with the monoclonal antibody FMC7, and occasional expression of the CD5-antigen; at least one third of cells in each case were positive with anti-cALLa (J5,CD10). Half the cases were referred as B-CLL but none had the typical B-CLL immunophenotype: weak SmIg, M-rosettes of greater than 50%, CD5 positive, FMC7 and J5 negative. The diagnosis of follicular lymphoma was confirmed by lymph node biopsy in seven of the 10 cases. The overall response to treatment was poor and five patients died within three years of diagnosis. This aggressive form of follicular lymphoma needs to be distinguished from B-CLL as different management is required. Images Fig 1 Fig 2 Fig 3 Fig 4 Fig 5 PMID:3056987

  11. Characterization of size, strength and structure of aluminum-polymer dual-coagulant flocs under different pH and hydraulic conditions.

    PubMed

    Rong, Hongyan; Gao, Baoyu; Dong, Min; Zhao, Yanxia; Sun, Shenglei; Yanwang; Yue, Qinyan; Li, Qian

    2013-05-15

    The objectives of this study are to investigate the impact of papermaking sludge product (LA) on coagulation performance and floc properties under different solution pH and hydraulic conditions. LA was synthetized by grafting acrylamide onto the lignin that contained in papermaking sludge. Characterization of LA, such as FTIR, SEM, zeta potential and molecular weight, showed that target product was obtained successfully. LA was used in combination with aluminum sulfate or polyaluminum chloride, namely Al-LA (Al was dosed firstly) and LA-Al (LA was dosed firstly), in humic acid water treatment. Floc properties and coagulation behaviors of aluminum salts and the dual-coagulants were comparatively evaluated. Results showed that DOC removal was improved by LA at pH 4 ~ 9 and the removal variations caused by different pH were decreased. Flocs formed at pH 5 and pH 8 gave quite large floc size. Floc recoverability declined as initial pH increased. Floc size, growth rate and recoverability were in the order of Al-LA>LA-Al>Al. Furthermore, flocs formed at pH 7 showed the weakest resistance to increasing shear force. Fractal dimension was rather high at pH 7 and 8 and it was in the following order: Al>LA-Al>Al-LA. PMID:23542601

  12. Stress fractures of the base of the metatarsal bones in young trainee ballet dancers

    PubMed Central

    Albisetti, Walter; De Bartolomeo, Omar; Tagliabue, Lorenzo; Camerucci, Emanuela; Calori, Giorgio Maria

    2009-01-01

    Classical ballet is an art form requiring extraordinary physical activity, characterised by rigorous training. These can lead to many overuse injuries arising from repetitive minor trauma. The purpose of this paper is to report our experience in the diagnosis and treatment of stress fractures at the base of the second and third metatarsal bones in young ballet dancers. We considered 150 trainee ballet dancers from the Ballet Schools of "Teatro Alla Scala" of Milan from 2005 to 2007. Nineteen of them presented with stress fractures of the base of the metatarsal bones. We treated 18 dancers with external shockwave therapy (ESWT) and one with pulsed electromagnetic fields (EMF) and low-intensity ultrasound (US); all patients were recommended rest. In all cases good results were obtained. The best approach to metatarsal stress fractures is to diagnose them early through clinical examination and then through X-ray and MRI. ESWT gave good results, with a relatively short time of rest from the patients’ activities and a return to dancing without pain. PMID:19415273

  13. Measurement of thermophysical properties coupled with LCA assessment for the optimization of a historical building retrofit

    NASA Astrophysics Data System (ADS)

    Bortolin, A.; Bison, P.; Cadelano, G.; Ferrarini, G.; Fortuna, S.

    2015-11-01

    Historical buildings are a significant part of the Italian building stock and, in most cases, need deep refurbishment interventions to reach the energy criteria required by the current standards. A workflow that integrates on-site surveys and building modeling is mandatory to obtain effective energy saving measures. This work describes the analysis and modeling of the San Vito alla Rivera church, a XIV century building that was damaged during 2009 L'Aquila earthquake, suffering a partial collapse of the façade and of the roof. The latter was selected for a complete restoration that could improve its thermal performance while maintaining, as much as possible, the original structure. Several elements of the roof were collected in situ in order to measure, in laboratory, its thermophysical properties applying standard techniques and alternative methods based on infrared thermography. The accurate characterization of the materials was the starting point for the estimation of the environmental impact of the retrofit aimed to reach a defined thermal transmittance. A model of the building was created with TRNSYS software to calculate the energy consumption before and after the intervention. A Life Cycle Assessment (LCA) analysis was conducted on different insulation materials to determine the one with the lowest impact.

  14. Padus, Sandalus, Gens Fadiena. Underwater Surveys in Palaeo-Watercourses (ferrara District - Italy)

    NASA Astrophysics Data System (ADS)

    Bucci, G.

    2015-04-01

    In the ambit of our program of researches on ancient rivers in Ferrara hinterland (Italy), we have been joining a Scientific - Didactic Project between Soprintendenza per i Beni Archeologici dell'Emilia Romagna, Comune di Portomaggiore Assessorato alla Cultura, CMAS A.CDCI. - Confédération Mondiale des Activités Subaquatiques Federation ITA F07 - Associazione CMAS Diving Center Italia. The Project is focused on underwater archaeological surveys in ex quarry lakes, following the Rivers Padus and Sandalus between Voghiera, Gambulaga and Portomaggiore (Ferrara District). Here we are going to introduce our most recent results, after the last immersions and a 3D bathymetrical survey completed by echo-side scan sonar in Tramonto Lake at Gambulaga, explaining the connection with remote sensing investigations and direct surveys applied to underwater archaeology of the inland water. The main submerged structure individuated is a part of wooden dock on the left side of Padus, in front of the Necropolis of Fadieni (1st-3rd cent. A.D.). Thanks to the study of 183 finds coming from the lake, involving students and young collaborators of the Archaeological National Museum of Ferrara, we are reconstructing the ancient landscape between Proto-Imperial Age and Late Antique.

  15. The Milky Way and the Local Group

    NASA Astrophysics Data System (ADS)

    Rampazzo, Roberto; D'Onofrio, Mauro; Zaggia, Simone; Lattis, James M.; van der Kruit, Pieter C.; Vallenari, Antonella; Calzetti, Daniela; Madore, Barry F.; Karachentseva, Valentina; Ibata, Rodrigo; Gallart, Carme; Lake, George; Tully, Brent R.; Gilmore, Gerald F.

    The beauty and the charm of the Milky May (MW) The Galaxy - Milky Way have been celebrated by countless poets and writers of many Countries along the centuries (see e.g. the beautiful anthology of Piero Boitani 2012 ). The stellar nature of the MW was firstly observed by Galileo. Galilei Galileo In 1610 in the Sidereus Nuncius ( Galilei 1993 ) Galileo wrote that the MW is "nient'altro che una congerie di innumerevoli Stelle, disseminate a mucchi; chè in qualunque regione di essa si diriga il cannocchiale, subito una ingente folla di Stelle si presenta alla vista, delle quali parecchi si vedono abbastanza grandi e molto distinte; ma la moltitudine delle piccole è del tutto inesplorabile". In the same paragraph, Galileo remarked that observations with his telescope, for the first time, wipe out centuries of philosophical discussions about the nature of the MW. Three more centuries have been necessary to complete a second radical Copernican Revolution that displaces the solar system from being roughly at the center of the MW and project this latter in the vast Universe populated by billions of similar spiral galaxies (see Chap. 1).

  16. Efficiency of nitrogen and phosphorus utilization in progenies of factorial crosses between European and exotic cultivars of spring barley (Hordeum vulgare L.).

    PubMed

    Górny, Andrzej G; Ratajczak, Dominika

    2008-01-01

    Previous observations suggested that some landraces, primitive cultivars and other barleys originating from the harsh conditions of the Middle East, North Africa and Tibet might serve as interesting sources of adaptation to low-input agriculture. This opportunity was verified in field experiments performed under reduced rates of nitrogen (N) and phosphorus (P) fertilization. Genetic variation in major components of the efficiency of N and P utilization was examined among F2 and F3 generations of crosses between four European female and seven exotic male lines of spring barley. Preponderance of general combining ability effects was found for most efficiency components, suggesting that the characters are mainly controlled by additive gene action. Non-additive effects appeared to be less or non-significant. Under reduced fertilization, hybrid progenies of the Syrian cv. M.Dingo/D.Alla 106 and the Moroccan cv. Moroc 9-75 exhibit an enhanced yielding and the highest capacity to utilize N and P efficiently in grain mass formation. The results proved that the exotic barleys appear to be particularly useful for breeding programs aiming at improved barley adaptation to less favourable fertilization regimes. PMID:19029682

  17. Statin safety: an appraisal from the adverse event reporting system.

    PubMed

    Davidson, Michael H; Clark, John A; Glass, Lucas M; Kanumalla, Anju

    2006-04-17

    The adverse event (AE) profiles of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor (statin) agents are of great interest, in particular the most recently approved statin, rosuvastatin. The forwarding of reports of AEs has been shown to be influenced by several reporting biases, including secular trend, the new drug reporting effect, product withdrawals, and publicity. Comparative assessments that use AE reporting rates are difficult to interpret under these circumstances, because such effects can themselves lead to marked increases in AE reporting. Consequently, many comparative reporting rate analyses are best carried out in conjunction with other metrics that put reporting burden into context, such as report proportion. All-AE reporting rates showed a temporal profile that resembled those of other statins when marketing cycle and secular trend were taken into account. A before-and-after cerivastatin withdrawal comparison showed a substantial increase in the reporting of AEs of interest for the statin class overall. Report proportion analyses indicated that the burden of rosuvastatin-associated AEs was similar to that for other statin agents. Analyses of monthly reporting rates showed that the reporting of rosuvastatin-associated rhabdomyolysis and renal failure have increased following AE-specific mass media publicity. Postrosuvastatin AE reporting patterns were comparable to those seen with other statins and did not resemble cerivastatin. PMID:16581327

  18. Kinetic Modelling of Parallel Electron Transport in TdeV.

    NASA Astrophysics Data System (ADS)

    Shoucri, M.; Shkarofsky, I.; Stansfield, B.; Batishchev, O.; Batishcheva, A.; Krasheninnikov, S.; Sigmar

    1996-11-01

    The 1D2V Fokker-Planck code ALLA [1] is used to model parallel electron transport in the SOL of TdeV. Our model uses detached and attached experimental data [2] given by Langmuir probes, Li ablation and He spectroscopy. We obtain the electron distribution function on a precise 257x65x60 non-uniform grid. Strong deviations of hydrogen and carbon excitation rates, and heat conduction coefficient from their Maxwellian values are shown. We compare the calculated variation of the effective temperature at the reciprocating probe position with experimental measurements. We also explain by non-local effects why different experimental techniques show differences in the electron temperature. altaffiltext [1] A.A.Batishcheva et al., Physics of Plasmas 3 (1996) 1634 altaffiltext [2] B.L.Stansfield et al., Proc. 22 Eur.Conf., Bornemouth, 19C pIII-101. *Supported by Government of Canada, Hydro-Québec and INRS. Work performed under USDoE contracts DE-FG02-91-ER-54109 at MIT and DE-FG02-88-ER-53263 at Lodestar.

  19. Landslide hazard prediction in the North-Eastern Apennines (Italy)

    NASA Astrophysics Data System (ADS)

    Disperati, L.; Guastaldi, E.; Rindinella, A.

    2003-04-01

    training dataset of occurrences and a test dataset, a cross validation is made. The valuation both for flows and slides was performed through Prediction Rate Curves (PRC). By utilising the occurrences of the test dataset, PRC derived from the relation between CF trend in the whole area (cumulative percentage), portion of total area and number of landslides. As result, engineering geology can be indicated as the dominant factor for PRC of flows; likewise engineering geology, land use and RBS combination is the more effective combination. On the other side, slope and aspect resulted less determinative in best PRC trend. Moreover, the combination of engineering geology and slope allowed the computation of best PRC for landslide. References CARMIGNANI L. (2001): Realizzazione della cartografia geologica e geotematica e dei relativi supporti informatici alla scala 1/10.000 -- Progetto 1 -- Zona Nord. Progetti strumentali alla funzione di ricostruzione. Interventi strutturali comunitari obiettivo 5b -- Misura 3.1.4 Azioni di ricostruzione e recupero del tessuto urbano infrastrutturale nei territori colpiti dal sisma (Azione 7). Contratto tra la Regione Marche -- Servizio Urbanistica e Cartografia e l'Università degli Studi di Siena. Rapporto Finale. Università degli Studi di Siena, Dipartimento di Scienze della Terra, Dicembre 200 1, pp. 6 I. CHUNG C. J. (1999): Prediction models in spatial data analysis for landslide hazard mapping -- Natural Resources Canada, Geological Survey of Canada-Mineral Resources Division-Spatial Data Analysis Laboratory, http://www.nrcan.gc.ca/gsc/mrd/sdalweb/landslides/index.htm. CHUNG C. J., FABBRI A.G. (1993): The representation of geoscience information for data integration. Non-renewable Resources, v. 2., n. 3, pp. 1 22-139. CHUNG C. J., FABBRI A.G., VAN WESTEN C.J (1995).- Multivariate regression analysis for landslide hazard zonation. In Carrara, A. and Guzzetti, F., eds.: "Geographical Information Systems in Assessing Natural Hazards

  20. How changes in nutrition have influenced the development of allergic diseases in childhood

    PubMed Central

    2012-01-01

    The increasing prevalence of allergic diseases in childhood in the last decades could be linked to concomitant dietary changes, especially with the modified and lower consumption of fruit, vegetables and minerals. The consumption of these foods by pregnant women and children in the first years of life seems to be associated with a reduced risk of asthma and related symptoms. Foods that can prevent the development of wheezing through their antioxidant effects contain vitamin C and selenium; blood levels of these elements correlate negatively with the risk of wheezing. Intake of vitamin E during pregnancy also appears to be correlated with a reduced risk of wheezing for the unborn child. Similarly, low intake of zinc and carotenoids by pregnant women is associated with an increased risk of wheezing and asthma in childhood. Fiber also has anti-inflammatory properties and protective effects against allergic diseases such as atopic dermatitis and asthma. The consumption of fat influences the development of the airways. Populations in Western countries have increased their consumption of n-6 PUFAs and, in parallel, reduced n-3 PUFAs. This has led to decreased production of PGE2, which is believed to have a protective effect against inflammation of the airways. Conflicting hypotheses also concern vitamin D; both an excess and a deficiency of vitamin D, in fact, have been associated with an increased risk of asthma. Further studies on the role of these substances are necessary before any conclusions can be drawn on a clinical level. Astratto La crescente prevalenza negli ultimi decenni delle malattie allergiche in età pediatrica potrebbe essere legata a concomitanti cambiamenti nella dieta, in particolare alla minore e modificata introduzione di frutta, verdura e minerali. Il consumo di questi alimenti da parte delle donne in gravidanza e dei bambini nei primi anni di vita sembra essere associato ad un ridotto rischio di asma e di sintomi correlati. Gli alimenti che

  1. Meningococco B: controllo di due focolai epidemici mediante vaccinazione

    PubMed Central

    2014-01-01

    Riassunto La problematica di un efficace approccio vaccinale nei confronti del Meningococco B (MenB) è stata superata identificando con la metodica della "reverse vaccinology" alcuni antigeni capaci di indurre una risposta verso la maggior parte dei ceppi di MenB circolanti nel mondo. Il nuovo vaccino MenB a 4 componenti (4CMenB) è stato autorizzato in Europa, Australia e Canada, ed è entrato nei calendari di immunizzazione pediatrica internazionali: Australia, Canada, UK. In Italia, le prime regioni che hanno raccomandato la vaccinazione contro il MenB sono state Basilicata e Puglia. La gestione di epidemie/focolai epidemici richiede la messa in atto di una risposta rapida da parte delle autorità sanitarie nei confronti di una emergenza sanitaria ad elevato impatto, anche emotivo, sulla popolazione, come recentemente dimostrato in due università americane. Alla dichiarazione di focolaio epidemico in atto, in entrambi i contesti si è attivata una procedura per l'uso del vaccino 4CMenB non ancora autorizzato negli USA. È stato così possibile organizzare gli interventi di profilassi attiva nei due campus universitari, adottando il primo impiego su larga scala del nuovo vaccino 4CMenB e conseguendo, in tempi relativamente brevi, elevati tassi di copertura vaccinale. A fronte di circa 14000 studenti immunizzati con almeno una dose, non è stata segnalata alcuna problematica di eventi avversi conseguenti all'immunizzazione; ad oggi non si sono verificati casi nei soggetti che hanno ricevuto il vaccino. Come conseguenza dei due focolai descritti, è oggi in corso la valutazione da parte dell'FDA per l'estensione dell'uso del vaccino 4CMenB negli Stati Uniti negli adolescenti e giovani adulti. PMID:25916017

  2. [I costi farmacologici della terapia di conversione con farmaci biologici nel carcinoma del colon-retto con metastasi epatiche].

    PubMed

    Giuliani, Jacopo; Bonetti, Andrea

    2016-08-01

    Riassunto. Lo scopo di questo studio è quello di valutare i costi dei farmaci (con particolare riferimento alle terapie con farmaci biologici) utilizzati nella terapia di conversione in una popolazione non selezionata di pazienti affetti da carcinoma del colon-retto in stadio avanzato, al fine di ottenere una resezione epatica R0. In questa rassegna sono stati selezionati i report completi e gli aggiornamenti di tutti gli studi clinici randomizzati (di fase II e fase III) che confrontassero almeno 2 regimi di terapia con farmaci biologici in prima linea in pazienti affetti da carcinoma del colon-retto in stadio avanzato di malattia. I costi dei farmaci sono stati ricavati dalla nostra Farmacia Ospedaliera e sono espressi in euro (€). Il nostro studio inizia con la valutazione di 683 abstract. 48 tria sono stati considerati adeguati per una successiva analisi. Una valutazione più approfondita ha portato all'esclusione di 37 trial, lasciando alla valutazione finale 11 studi clinici randomizzati (3 trial di fase II, per un totale di 522 pazienti, e 8 studi di fase III, per un totale di 7191 pazienti). I costi dei farmaci utilizzati nella terapia di conversione aumentano con la sostituzione del 5-fluorouracile con la capecitabina e, in misura maggiore, con l'introduzione degli agenti biologici. In questo lavoro sono presentati due punti chiave. Primo, i costi degli agenti farmacologici utilizzati nei regimi di prima linea a base di agenti biologici più comunemente utilizzati nel trattamento del carcinoma del colon-retto in stadio avanzato sono molto variabili. Secondo, i dati di efficacia dei regimi pubblicati, in termini di tassi di resezione, dipendono dalla selezione dei pazienti, dalle caratteristiche del tumore e dal tipo di schema di terapia. PMID:27571559

  3. SIg-E- ("null-cell") non-Hodgkin's lymphomas. Multiparametric determination of their B- or T-cell lineage.

    PubMed Central

    Knowles, D. M.; Dodson, L.; Burke, J. S.; Wang, J. M.; Bonetti, F.; Pelicci, P. G.; Flug, F.; Dalla-Favera, R.; Wang, C. Y.

    1985-01-01

    The authors performed immunophenotypic, functional, and molecular analysis of the neoplastic cells from 20 cases of SIg-, E-("null-cell") non-Hodgkin's lymphoma (NHL) in order to determine their lineage, better define this category of NHL, and evaluate the lineage specificity of selected phenotypic markers and the individual and collective utility of these approaches. They assigned 4 cases to the T-cell lineage, and 15 cases to the B-cell lineage, and 1 case remained indeterminant on the basis of immunophenotypic analysis. The cells from 2 cases assigned to the T-cell lineage expressed unusual phenotypes, but their T-cell derivation was confirmed by the demonstration of helper function in vitro. The 15 cases assigned to the B-cell lineage expressed a variety of B-cell-associated antigens, consistent with various stages of B-cell differentiation. Monoclonal antibodies OKT3, OKT4, OKT6, and OKT8 exhibited T-cell lineage restriction; and monoclonal antibodies OKB2, BL1, and B1 exhibited B-cell lineage restriction. Ia, TdT, cALLa, OKT9, and OKT10 exhibited lineage infidelity. Southern blot analysis for immunoglobulin heavy chain gene rearrangements confirmed 18 of the 19 lineage assignments made by immunophenotypic analysis and suggested that the 1 case of indeterminate phenotype was a B-cell neoplasm. One T-cell (OKT3+, T4+) neoplasm exhibited rearranged immunoglobulin heavy chain genes. Thus, neither immunophenotypic analysis nor the demonstration of rearranged immunoglobulin heavy chain genes alone permitted the satisfactory lineage assignment of every case of SIg-, E- NHL. However, combined immunophenotypic, functional, and genotypic analysis allowed us to assign every SIg-, E-NHL to the B- or T-cell lineage and to demonstrate that truly "null-cell" NHLs are probably very uncommon. Images Figure 1 Figure 2 Figure 3 Figure 4 PMID:2931028

  4. Geophysical techniques in the historical center of Venice (Italy): preliminary results from HVSR and multichannel analysis of surface waves

    NASA Astrophysics Data System (ADS)

    Trevisani, Sebastiano; Rocca, Michele; Boaga, Jacopo

    2014-05-01

    This presentation aims to outline the preliminary findings related to an extensive seismic survey conducted in the historical center of Venice, Italy. The survey was conducted via noninvasive and low-cost seismic techniques based on surface waves analysis and microtremor methods, mainly using single station horizontal to vertical spectral ratio techninques (HVSR) and multichannel analysis of surface waves in passive (ReMI) and active (MASW) configurations. The importance and the fragility of the cultural heritage of Venice, coupled with its peculiar geological and geotechnical characteristics, stress the importance of a good knowledge of its geological architecture and seismic characteristics as an opportunity to improve restoration and conservation planning. Even if Venice is located in a relatively low seismic hazard zone, a local characterization of soil resonance frequencies and surficial shear waves velocities could improve the planning of engineering interventions, furnishing important information on possible local effects related to seismic amplification and possible coupling within buildings and soil resonance frequencies. In the specific we collected more than 50 HVSR single station noise measurements and several passive and active multichannel analysis of surface waves located in the historical center. In this work we report the characteristics of the conducted seismic surveys (instrumentation, sampling geometry, etc.) and the preliminary findings of our analysis. Moreover, we discuss briefly the practical issues, mainly of logistic nature, of conducting this kind of surveys in a peculiar and crowed historical center as represented by Venice urban contest. Acknowledgments Instrumentation acquired in relation to the project co-financed by Regione Veneto, POR-CRO, FESR, 2007-2013, action 1.1.1. "Supporto ad attività di ricerca, processi e reti di innovazione e alla creazione di imprese in settori a elevato contenuto tecnologico"

  5. Immunophenotypic heterogeneity of multiple myeloma: influence on the biology and clinical course of the disease. Castellano-Leones (Spain) Cooperative Group for the Study of Monoclonal Gammopathies.

    PubMed

    San Miguel, J F; González, M; Gascón, A; Moro, M J; Hernández, J M; Ortega, F; Jimenez, R; Guerras, L; Romero, M; Casanova, F

    1991-02-01

    In 112 untreated myeloma patients we have analysed the immunophenotype of plasma cells both by immunofluorescence (IF) and immunocytochemistry (APAAP). Both techniques yielded similar results pointing to an important degree of heterogeneity in antigenic expression not only between different patients but also within the same patient. The expression of CD38 and Han-PC1 antigens (Ags) was almost constant (greater than 90% positive cases), while CD9 was detected in 66% of the cases. On the other hand, less than one third of patients were positive for CD10, CD20 and HLA-DR and generally with a weak expression (less than 30% positive plasma cells). In occasional cases plasma cells were weakly positive for the myelomonocytic markers CD13 (9%), CD15 (25%) and CD14 (6%). The possibility that this heterogeneity might be the result of different stages of differentiation of the neoplastic clone is suggested both by the positive correlation in the expression of some of these antigens (CD10, CD9, CD20, HLA-DR) and by the relationship between CD10 and myeloid antigens with immature plasma cell morphology. Finally, the cALLA antigen does not seem to be of significant value in predicting survival. Moreover, none of the other markers explored showed a clear influence in the course of the disease, although the tendency towards a lower survival found for the CD20+ cases as well as the association of the expression of some antigens and advanced clinical stage, may warrant further studies in a larger series of patients. PMID:1706197

  6. Maternal age and intracytoplasmic sperm injection outcome in infertile couples at Khartoum, Sudan

    PubMed Central

    Ahmed, Mohamed; Shareef, Osama; Adam, Ishag; Rayis, Duria

    2015-01-01

    Background Intracytoplasmic sperm injection (ICSI) was considered as the mainstay of treatment for male infertility. Nowadays, the scope of ICSI has been widened to include other causes of infertility. There are few published data on ICSI in countries with low incomes. Aims A cross-sectional study was conducted at Saad AbuAlla and Banoun Centers, Khartoum, Sudan to investigate outcomes of ICSI and to determine the parameters that might predict pregnancy success rate following ICSI. Methods The study included 191 infertile couples who underwent 296 ICSI cycles between 1st April 2013 and 31 March 2014. Results One hundred and ninety one couples (comprising 296 cycles of ICSI) were enrolled to the study. The mean (SD) number of retrieved oocytes was 9.7 (7.5).  The mean (SD) number of transferred embryos was 2.9 (1.0). Out of these, 50 (26.2%) and 40 (20.9%) had chemical and clinical pregnancy, respectively. Thirty–six couples (18.8%) and five couples (2.6%) had miscarriage and had ectopic pregnancy, respectively. Under logistic regression, younger age (OR = 0.8, 95% CI= 0.81 ─ 0.96, P = 0.004) and endometrial thickness (OR = 1.3, 95% CI= 1.07─1.60, P = 0.009) were the significant predictors for the success of ICSI in inducing pregnancy. Conclusion                 The rates of successful fertilisation and pregnancy-to-term rates in this setting depend mainly on the maternal age. PMID:27347370

  7. Phase diagram of the itinerant helical magnet MnSi at high pressures and strong magnetic fields

    NASA Astrophysics Data System (ADS)

    Stishov, Sergei

    We performed a series of resistivity, heat capacity and ultrasound speed measurements of a MnSi single crystal at high pressures and strong magnetic fields [1-3]. Two notable features of the phase transition in MnSi that disappear on pressure increasin are a sharp peak marking the first order phase transition and a shallow maximum, situated slightly above the critical temperature and pointing to the domain of prominent helical fluctuations. The longitudinal and transverse ultrasound speeds and attenuation were measured in a MnSi single crystal in the temperature range of 2-40 K and magnetic fields to 7 Tesla. The magnetic phase transition in MnSi in zero magnetic field is signified by a quasi-discontinuity in the c11 elastic constant, which almost vanishes at the skyrmion - paramagnetic transition at high magnetic fields. The powerful fluctuations at the minima of c11 make the mentioned crossing point of the minima and the phase transition lines similar to a critical end point, where a second order phase transition meets a first order one.

  8. Enceladus Heat Pump Model

    NASA Astrophysics Data System (ADS)

    Matson, Dennis L.; Johnson, T. V.; Lunine, J. I.; Castillo-Rogez, J. C.

    2010-10-01

    Plume gas composition and the presence of dust grains rich in sodium salts [1,2] support a subsurface liquid as the source of the plumes observed at the South pole of Enceladus. We suggest that seawater circulating from the ocean to the surface supplies water, gas, dust and heat to the plumes. Our model needs only a percent or two of gas dissolved in the ocean, a value that is very much consistent with available observations ([1] suggest 10 percent of various gas species in the plume). As seawater comes up, pressure is released and bubbles form. Bubbly seawater is less dense than ice. Expanding gas provides lifting energy (cf. [6], [7]). The model delivers the materials that Postberg et al. [2] use for plume eruptions. Popping bubbles throw a fine spray that contains salt. This aerosol exits with the plume gas [2]. Most significant is the south polar heat flow >15 GW [4]. Water-borne oceanic heat is transferred to the surface ice. Less this heat, the water becomes colder, dissolves the bubble gases and becomes dense. It returns to the ocean via cracks in the ice. A large volume of ice is accessible via cracks SO THAT chemical interactions, heat exchange and other processes are possible. [1] Waite Jr et al., Nature, 460, 487 (2009). [2] Postberg et al., Nature, 459, 1098 (2009). [4] Howett et al BAAS., 41, 1122 (2009). [6] Crawford, and Stevenson, Icarus, 73, 66 (1988). [7] Murchie, and Head, LPS XVII, 583 (1986). This work was conducted at the Jet Propulsion Laboratory, California Institute of Technology under NASA contract, and for JIL under "Incentivazione alla mobilita' di studiosi straineri e italiani residenti all'estero" of Italy.

  9. Application of the FADS system on the Re-entry Module

    NASA Astrophysics Data System (ADS)

    Zhen, Huang

    2016-07-01

    The aerodynamic model for Flush Air Data Sensing System (FADS) is built based on the surface pressure distribution obtained through the pressure orifices laid on specific positions of the surface,and the flight parameters,such as angle of attack,angle of side-slip,Mach number,free-stream static pressure and dynamic pressure are inferred from the aerodynamic model.The flush air data sensing system (FADS) has been used on several flight tests of aircraft and re-entry vehicle,such as,X-15,space shuttle,F-14,X-33,X-43A and so on. This paper discusses the application of the FADS on the re-entry module with blunt body to obtain high-precision aerodynamic parameters.First of all,a basic theory and operating principle of the FADS is shown.Then,the applications of the FADS on typical aircrafts and re-entry vehicles are described.Thirdly,the application mode on the re-entry module with blunt body is discussed in detail,including aerodynamic simulation,pressure distribution,trajectory reconstruction and the hardware shoule be used,such as flush air data sensing system(FADS),inertial navigation system (INS),data acquisition system,data storage system.Finally,ablunt module re-entry flight test from low earth orbit (LEO) is planned to obtain aerodynamic parameters and amend the aerodynamic model with this FADS system data.The results show that FADS system can be applied widely in re-entry module with blunt bodies.

  10. Calibrazioni a terra e prestazioni in volo di spettrometri ad immagine nel visibile e nel vicino infrarosso per l'esplorazione planetaria

    NASA Astrophysics Data System (ADS)

    Filacchione, Gianrico

    2006-10-01

    Nel corso dell’ultimo decennio l’esplorazione planetaria ha potuto beneficiare dei dati prodotti dagli spettrometri ad immagine: grazie a questa nuova classe di strumenti, realizzati per l’osservazione in remoto di superfici ed atmosfere planetarie, è possibile acquisire dati iperspettrali con elevati poteri risolutivi spaziali e spettrali. Il principale vantaggio offerto dagli spettrometri ad immagine, rispetto alle camere ed agli spettrometri puntuali, è rappresentato dalla capacità di misurare, identificare e mappare le unità composizionali delle superfici planetarie; queste informazioni permettono di investigare sia l’evoluzione geochimica delle superfici sia la dinamica e la composizione delle atmosfere. Sebbene i primi spettrometri ad immagine siano stati francesi (Phobos/ISM, Imaging Spectrometer for Mars) e statunitensi (Galileo/NIMS, Near Infrared Mapping Spectrometer), il nostro paese nel corso degli ultimi anni è stato in grado di proporre alla com unità spaziale internazionale degli strumenti dalle elevate prestazioni che sono stati infatti accettati come payload scientifici su diverse missioni interplanetarie: dai canali visibili di VIMS (Visual and Infrared Mapping Spectrometer) su Cassini (Nasa, JPL, ESA, ASI) e di OMEGA (Observatoire pour la Minéralogie, l’Eau, les Glacies et l’Activitè de Mars) su MarsExpress (ESA) ai due VIRTIS (Visible and Infrared Thermal Imaging Spectrometer) su Rosetta (ESA) e VenusExpress (ESA) fino a VIR-MS (Visible and Infrared Mapping Spectrometer) su Dawn (Nasa). In questo momento inoltre altri due spettrometri sono in avanzata fase di studio: JIRAM (Jovian InfraRed Auroral Mapper) su Juno (missione New Discovery Nasa) e VIHI (Visible and Infrared Hyperspectral Imager) integrato nel payload italiano di remote sensing SIMBIO-SYS di BepiColombo (missione cornerstone ESA). La realizzazione di uno spettrometro ad immagini da utilizzare su una missione interplanetaria richiede un’accurata analisi in fase

  11. The origin of the Dargom canal in the oasis of Samarkand (Uzbekistan). A new scenario from geoarcheological data

    NASA Astrophysics Data System (ADS)

    Marconi, V.; Mantellini, S.; Picotti, V.; Gabbianelli, G.; Tosi, M.

    2009-04-01

    As the main oases developed in the arid regions of Central Asia, the region of Samarkand is the outcome of large hydraulic works carried out since the past times. The main result of such a great landscape transformation is a complex irrigation network formed by several artificial channels and useful for both urban water supply and irrigation purposes. Within the framework of the Italo-Uzbek Archaeological Project begun in 2001, a specific study was aimed to reconstruct the history of Dargom, the primary canal on the South of the city, and its relationships with the settlement dynamics. According to the most accepted theories, the Dargom was dug during the Achaemenid Age (6th-4th c. BC) as a consequence of a master plan linked to a strong central political power. The new investigations carried out by a joined team of Archaelogists and Geologists from the University Bologna allowed a new hypothesis on the way of digging and the chronology of the Dargom itself. The analyses on the historical settlement patterns seem to suggest a low development of Samarkand's territory during the Achaemenid times, whilst the increasing of sites during the Early Middle Age (5th-8th c.) can be explained throughout the rich trades along the Silk Road as well as the development of irrigated agriculture. The present-day Dargom is a high sinuosity channel deeply incised into the bedrock flowing to the east, strongly resembling a natural channel. It has been excavated for around 70 km along an apron of alluvial fans sourced by a southern mountain range. Its morphology clearly document a natural evolution after excavation: incision and meandering took place, likely due to the increasing gradient related to the headward migration of lowering of the base-level and the decrease of the bed load through time. Field survey around the fortress of Kafir Kala, the main archeological site geographically linked to the Dargom, allowed reconstructing the original bed of the canal, marked by a layer of

  12. [Psicopatologia, fattori psicosociali e obesità].

    PubMed

    Pinna, Federica; Sardu, Claudia; Orrù, Walter; Velluzzi, Fernanda; Loviselli, Andrea; Contu, Paolo; Carpiniello, Bernardo

    2016-01-01

    fattori aumenta questo rischio. Pur tenendo conto dei limiti dovuti alla natura trasversale dello studio, questi risultati sono collegati a implicazioni importanti sia ai fini della prevenzione sia del trattamento dell'obesità. PMID:27030347

  13. A sputnik IV saga

    NASA Astrophysics Data System (ADS)

    Lundquist, Charles A.

    2009-12-01

    The Sputnik IV launch occurred on May 15, 1960. On May 19, an attempt to deorbit a 'space cabin' failed and the cabin went into a higher orbit. The orbit of the cabin was monitored and Moonwatch volunteer satellite tracking teams were alerted to watch for the vehicle demise. On September 5, 1962, several team members from Milwaukee, Wisconsin made observations starting at 4:49 a.m. of a fireball following the predicted orbit of Sputnik IV. Requests went out to report any objects found under the fireball path. An early morning police patrol in Manitowoc had noticed a metal object on a street and had moved it to the curb. Later the officers recovered the object and had it dropped off at the Milwaukee Journal. The Moonwarch team got the object and reported the situation to Moonwatch Headquarters at the Smithsonian Astrophysical Observatory. A team member flew to Cambridge with the object. It was a solid, 9.49 kg piece of steel with a slag-like layer attached to it. Subsequent analyses showed that it contained radioactive nuclei produced by cosmic ray exposure in space. The scientists at the Observatory quickly recognized that measurements of its induced radioactivity could serve as a calibration for similar measurements of recently fallen nickel-iron meteorites. Concurrently, the Observatory directorate informed government agencies that a fragment from Sputnik IV had been recovered. Coincidently, a debate in the UN Committee on Peaceful Uses of Outer Space involved the issue of liability for damage caused by falling satellite fragments. On September 12, the Observatory delivered the bulk of the fragment to the US Delegation to the UN. Two days later, the fragment was used by US Ambassador Francis Plimpton as an exhibit that the time had come to agree on liability for damage from satellite debris. He offered the Sputnik IV fragment to USSR Ambassador P.D. Morozov, who refused the offer. On October 23, Drs. Alla Massevitch and E.K. Federov of the USSR visited the

  14. Assimilation of multiple river flow data for enhanced operational flood forecasts

    NASA Astrophysics Data System (ADS)

    Ercolani, Giulia; Castelli, Fabio

    2016-04-01

    that is minimized during the variational assimilation procedure.Results show that more significant improvements are obtained in floods events than in false alarms. For instance, error on peak flow reduces respectively of about 30% and 20% (lead time of nearly 20 hours) at the measurement station that is representative of river network outlet (S. Giovanni alla Vena).The best performances correspond to single peak flood events, while in some more complex cases DA does not significantly improve modeled discharges, possibly because of shortcomings in model structure.Forecasts at downstream locations enhance especially when peak flow of the main upstream tributaries is included in the assimilation window. In conclusion, the operational hydrologic forecasting chain can effectively benefits from the developed assimilation system, although in the limit of the model structure.

  15. Calorimetria nucleare in collisioni tra ioni pesanti ad energie intermedie

    NASA Astrophysics Data System (ADS)

    Spezzi, L.

    2002-07-01

    Nel presente lavoro di tesi ci si e' occupati di uno studio sistematico di misure di temperatura ed energia di eccitazione in sistemi nucleari formati in reazioni tra ioni pesanti ad energie intermedie. La temperatura a stata misurata tramite due diversi metodi: rapporto tra le rese di isotopi che differiscono di uno stesso numero di nucleoni ( d/t-3He/4He , 3He/4He -6Li/7Li) - temperatura isotopica -, e rapporto tra le popolazioni degli stati eccitati in frammenti instabili (5Li e 6Li) che decadono in particelle leggere in coincidenza - temperatura di emissione. Le misure in esame sono state effettuate presso i Laboratori Nazionali del Sud per i sistemi 93Nb+93Nb, 93Nb+116,124Sn, 116,120Sn+116,124Sn e 116Sn+93Nb ad energie comprese tra 17 e 40 A MeV. L'apparato di rivelazione era costituito da un odoscopio ad alta granularite (96 telescopi Si (50micron)-Si(300micron)-CsI(Tl) ) e basse soglie di rivelazione, utilizzato sia per identificare risonanze in frammenti eccitati che per misure di rese di isotopi di frammenti con 2<=Z<=6, e dal multirivelatore FIASCO che, grazie alla misura contemporanea di posizione e tempo di volo dei frammenti provenienti dal proiettile (PLF - Projectile Like Fragments) e dal bersaglio (TLF - Target Like Fragment), e' stato utilizzato per misurare direttamente l'energia di eccitazione del sistema in studio. Analisi precedenti, condotte nell'ambito di varie collaborazioni, hanno messo in evidenza la possible esistenza di una transizione di fase liquido-gas del primo ordine nella materia nucleare. In tale contesto, ci siamo occupati di una verifica della curva calorica nucleare, ovvero della correlazione esistente fra temperatura ed energia di eccitazione del sistema, indagando, nel contempo, sulla sua dipendenza dalla massa del sistema che si frammenta. Si e' effettuato, inoltre, un confronto fra i due diversi metodi di misura della temperatura (temperatura isotopica e di emissione): l'andamento plateau-like della curva calorica e' stato

  16. MN112: a new Galactic candidate luminous blue variable

    NASA Astrophysics Data System (ADS)

    Gvaramadze, V. V.; Kniazev, A. Y.; Fabrika, S.; Sholukhova, O.; Berdnikov, L. N.; Cherepashchuk, A. M.; Zharova, A. V.

    2010-06-01

    We report the discovery of a new Galactic candidate luminous blue variable (cLBV) via detection of an infrared circular nebula and follow-up spectroscopy of its central star. The nebula, MN112, is one of many dozens of circular nebulae detected at 24μm in the Spitzer Space Telescope archival data, whose morphology is similar to that of nebulae associated with known (c)LBVs and related evolved massive stars. Specifically, the core-halo morphology of MN112 bears a striking resemblance to the circumstellar nebula associated with the Galactic cLBV GAL079.29+00.46, which suggests that both nebulae might have a similar origin and that the central star of MN112 is an LBV. The spectroscopy of the central star showed that its spectrum is almost identical to that of the bona fide LBV PCygni, which also supports the LBV classification of the object. To further constrain the nature of MN112, we searched for signatures of possible high-amplitude (>~1mag) photometric variability of the central star using archival and newly obtained photometric data covering a 45-yr period. We found that the B magnitude of the star was constant within error margins, while in the I band the star brightened by ~=0.4mag during the last 17 yr. Although the non-detection of large photometric variability leads us to use the prefix `candidate' in the classification of MN112, we remind the readers that the long-term photometric stability is not unusual for genuine LBVs and that the brightness of PCygni remained relatively stable during the last three centuries. Partially based on observations collected at the German-Spanish Astronomical Center, Calar Alto, jointly operated by the Max-Planck-Institut für Astronomie Heidelberg and the Instituto de Astrofísica de Andalucía (CSIC). E-mail: vgvaram@mx.iki.rssi.ru (VVG); akniazev@saao.ac.za (AYK); fabrika@sao.ru (SF); olga@sao.ru (OS); berdnik@sai.msu.ru (LNB); cher@sai.msu.ru (AMC); alla@sai.msu.ru (AVZ)

  17. FAMeS: Fidelity of Analysis of Metagenomic Samples

    DOE Data Explorer

    Hardy, Isidore Rigoutsos, Asaf Salamov, Frank Korzeniewski, Miriam Land, Alla Lapidus, Igor Grigoriev, Paul Richardson, Philip Hugenholtz, Nikos C Kyrpides, Nature Methods 2007 Jun;4(6):495-500.

  18. The ``Perrier Oceans'' Of Europa And Enceladus (Invited)

    NASA Astrophysics Data System (ADS)

    Matson, D.; Johnson, T. V.; Lunine, J. I.; Castillo, J. C.

    2010-12-01

    NASA contract, and for JIL under "Incentivazione alla mobilita' di studiosi straineri e italiani residenti all'estero" of Italy.

  19. Characterizing coal beds in western Kentucky with the Al-La-Sc coherent triad

    USGS Publications Warehouse

    Chyi, L.L.; Medlin, J.H.

    1996-01-01

    Cyclic sedimentation and lateral facies changes make coal bed correlations inconclusive and difficult. This uncertainty can be further complicated if a coal basin has been structurally deformed. Coal macerals can be studied to indicate the nature and degree of coalification. Their use in coal bed correlation, however, is limited. Most of the trace elements and their ratios that have been studied show significant within-bed lateral and stratigraphic variations, and thus are not effective in correlating coal beds regionally. Geochemically coherent groups of elements, such as rare earth elements (REE) and platinum group elements (PGE), appear to be highly differentiated in coal-forming environments. Geochemical coherent elemental triads appear to be useful for coal bed identification or fingerprinting. The best triad which was demonstrated to be effective in coal bed characterization in western Kentucky, is that of Al, La and Sc. These three elements are highly correlated with one another and they can be determined accurately and simultaneously with instrumental neutron activation analysis (INAA). The elemental triad Al-La-Sc is used to identify and fingerprint three key coal beds in western Kentucky: the Springfield (western Kentucky No. 9), the Davis (western Kentucky No. 6), and the Mining City and Dawson Springs are both considered to be the No. 4 coal bed in western Kentucky). Four distinct groupings can be recognized by use of the Al-La-Sc triad. The Dawson Springs coals have the highest Al/(La + Sc) ratios, followed by the Springfield, the Davis and the Mining City. The Mining City coal bed generally has the highest La/Sc ratio. However, the Dawson Springs is not correlated with the Mining City using the triad analysis, even though they have reportedly similar stratigraphic positions in the western Kentucky coal basin. The Al-La-Sc triad appears to be effective in discriminating between the Springfield and the Davis coal beds throughout the entire Illinois

  20. Two-Dimensional Combinatorial Screening (2DCS) of a Bacterial rRNA A-site-like Motif Library: Defining Privileged Asymmetric Internal Loops that Bind Aminoglycosides

    PubMed Central

    Tran, Tuan; Disney, Matthew D.

    2010-01-01

    RNAs have diverse structures that are important for biological function. These structures include bulges and internal loops that can form tertiary contacts or serve as ligand binding sites. The most commonly exploited RNA drug target for small molecule intervention is the bacterial ribosome, more specifically the ribosomal RNA aminoacyl-tRNA site (rRNA A-site) which is a major target for the aminoglycoside class of antibiotics. The bacterial A-site is composed of a 1×1 nucleotide all-U internal loop and a 2×1 nucleotide all-A internal loop separated by a single GC base pair. Therefore, we probed the molecular recognition of a small library of four aminoglycosides for binding a 16384-member bacterial rRNA A-site-like internal loop library using Two-Dimensional Combinatorial Screening (2DCS). 2DCS is a microarray-based method that probes RNA and chemical spaces simultaneously. These studies sought to determine if aminoglycosides select their therapeutic target if given a choice of binding all possible internal loops derived from an A-site-like library. Results show that the bacterial rRNA A-site was not selected by any aminoglycoside. Analyses of selected sequences using the RNA Privileged Space Predictor (RNA-PSP) program show that each aminoglycoside preferentially binds different types of internal loops. For three of the aminoglycosides, 6″-azido-kanamycin A, 5-O-(2-azidoethyl) neamine, and 6″-azido-tobramycin, the selected internal loops bind with ~10-fold higher affinity than the bacterial rRNA A-site. The internal loops selected to bind 5″-azido-neomycin B bind with similar affinity as the therapeutic target. Selected internal loops that are unique for each aminoglycoside have dissociation constants ranging from 25 to 270 nM and are specific for the aminoglycoside they were selected to bind compared to the other arrayed aminoglycosides. These studies further establish a database of RNA motifs that are recognized by small molecules that could be used to

  1. Neoproterozoic tectonic evolution of the Jebel Saghro and Bou Azzer - El Graara inliers, eastern and central Anti-Atlas, Morocco

    USGS Publications Warehouse

    Walsh, Gregory J.; Aleinikoff, John N.; Harrison, Richard W.; Burton, William C.; Quick, James E.; Benziane, Foudad; Yazidi, Abdelaziz; Saadane, Abderrahim

    2012-01-01

    much of the lower Ouarzazate Supergroup volcanic rocks in the area are probably related to caldera out-flow facies and collapse. Late stage PA3 intrusive rocks include the Bouskour–Sidi Flah and Timijt rhyolitic dike swarms at about 563 Ma, the voluminous pink Isk-n-Alla granite (559 ± 5 Ma), and volumetrically minor gabbro of Tagmout (556 ± 5 Ma). Rhyolite flows from the upper part of the Ouarzazate Supergroup, above a regional angular unconformity, yielded ages of 558 ± 4 and 556 ± 4 Ma. The youngest ages place an upper limit on block faulting and weak folding during latest Pan-African tectonic activity (PA3), coincident with the departure of the Cadomian crustal fragment from the northern margin of the WAC.

  2. The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial

    PubMed Central

    2012-01-01

    recruited in IST-3, despite the early hazards, thrombolysis within 6 h improved functional outcome. Benefit did not seem to be diminished in elderly patients. Funding UK Medical Research Council, Health Foundation UK, Stroke Association UK, Research Council of Norway, Arbetsmarknadens Partners Forsakringsbolag (AFA) Insurances Sweden, Swedish Heart Lung Fund, The Foundation of Marianne and Marcus Wallenberg, Polish Ministry of Science and Education, the Australian Heart Foundation, Australian National Health and Medical Research Council (NHMRC), Swiss National Research Foundation, Swiss Heart Foundation, Assessorato alla Sanita, Regione dell'Umbria, Italy, and Danube University. PMID:22632908

  3. Sediment yield estimation in mountain catchments of the Camastra reservoir, southern Italy: a comparison among different empirical methods

    NASA Astrophysics Data System (ADS)

    Lazzari, Maurizio; Danese, Maria; Gioia, Dario; Piccarreta, Marco

    2013-04-01

    using sediment storage in reservoirs provides a good opportunity: i) to test the reliability of the empirical methods used to estimate the sediment yield; ii) to investigate the catchment dynamics and its spatial and temporal evolution in terms of erosion, transport and deposition. References Ciccacci S., Fredi F., Lupia Palmieri E., Pugliese F., 1980. Contributo dell'analisi geomorfica quantitativa alla valutazione dell'entita dell'erosione nei bacini fluviali. Bollettino della Società Geologica Italiana 99: 455-516. Mitasova H, Hofierka J, Zlocha M, Iverson LR. 1996. Modeling topographic potential for erosion and deposition using GIS. International Journal of Geographical Information Systems 10: 629-641. Renard K.G., Foster G.R., Weesies G.A., McCool D.K., Yoder D.C., 1997. Predicting soil erosion by water: a guide to conservation planning with the Revised Universal Soil Loss Equation (RUSLE), USDA-ARS, Agricultural Handbook No. 703.

  4. New disposition for pain therapy in Italy, center for headache should be integrated in the network.

    PubMed

    Gensini, Gian Franco

    2011-05-01

    On March 15th 2010, Italy adopted the Law no. 38 "Disposizioni per garantire l'accesso alle cure palliative e alla terapia del dolore" (Provisions aimed at ensuring access to palliative care and pain therapy). The aim of pain therapy is to enable patients with chronic diseases to achieve pain control. Palliative care, as defined by the World Health Organization, aims at "improving the quality of life of patients and families, who face the problems associated with incurable diseases, through prevention and relief from suffering, achieved through an early identification and treatment of pain by pharmacological medication and other physical, psychosocial and spiritual techniques". The main issues addressed by the law concern the monitoring of pain (the doctors will have to record on the clinical report form every level of pain intensity suffered by the patient, the appropriate therapy administered, and the pain relief achieved. This report must be kept accurately in all settings: hospital, day hospital and in outpatients). The law also suggests the establishment of two kinds of regional networks. One network (including Hospices) ensures the administration of palliative care to terminally ill patients; the other, including clinics and centers of pain therapy, provides assistance to patients with chronic pain. These networks involve general practitioners, hospital specialists and pain therapy specialists in order to ensure the best patient care. Simplification of the prescription of opiate drugs is also included in the law. In the prescription of opiates, the National Health Service medical staff can use the normal prescription form, and opiates will reimbursed by the NHS, like all other drugs. In addition, the technical papers provide precise indications of the appropriate modality of administration. The law allocates (art. 12, paragraph 2) 100 million euros per year and € 2,450,000 in the biennium 2010-2011 to implement experimental regional projects: "hospital

  5. Geomorpho-Landscapes

    NASA Astrophysics Data System (ADS)

    Farabollini, Piero; Lugeri, Francesca; Amadio, Vittorio

    2014-05-01

    value -referring to biodiversity, geodiversity, culture- which can be considered as a special heritage. Starting from the concept of Geomorphosite, a geomorphologic landform with a scientific, cultural and socio-economical value (Panizza 2001), we propose a further definition, useful in the preliminary steps of the landscape analysis: "geomorpho-landscape" as a spatial object or component of a geological landscape, whose geo-morphological evolution, linked to the geological setting, are elements of aesthetical, semiological as well as historical and cultural value. The structure of the landscape is represented by the physical shape and spatial organization, in dynamic way: it is necessary to provide a readout of the landscape components that supplements the geo-morphological, lithological, geodiversity data (Lugeri et alii, 2012). The concept of "geomorpho-landscape" is conceived to address the need to describe by a synthetic approach the geological processes emerging at the landscape scale, allowing to link spatial patterns to geological processes Each geo-form has in itself geological, geo-morphological, landmark, historical and cultural features, of such special relevance, that they can be defined in terms of scientific quality, rarity, aesthetic appeal and educational and cultural value. Reference List AMADIO V. (2003). Analisi di sistemi e progetti di paesaggio. Franco Angeli, Milano, pp 236 AMADIO V, AMADEI M, BAGNAIA R, DI BUCCI D, LAURETI L, LISI A, LUGERI FR, LUGERI N. (2002). The role of Geomorphology in Landscape Ecology: The Landscape Unit Map of Italy', Scale 1: 250,000 ("Carta della Natura" Project). In: Allison RJ (ed) Applied Geomorphology: theory and practice. John Wiley & Sons, London, pp 265-282 APAT (2003). Carta della natura alla scala 1:250,000: metodologie di realizzazione. APAT, Manuali e linee guida 17/2003, Roma, pp 103 LUGERI F.R., FARABOLLINI P., GRAVIANO G. & AMADIO V. (2012). Geoheritage: Nature and culture in a landscape approach. European

  6. Effect of thrombolysis with alteplase within 6 h of acute ischaemic stroke on long-term outcomes (the third International Stroke Trial [IST-3]): 18-month follow-up of a randomised controlled trial

    PubMed Central

    2013-01-01

    the groups in visual analogue scale score and the proportion living at home were not significant. Interpretation IST-3 provides evidence that thrombolysis with intravenous alteplase for acute ischaemic stroke does not affect survival, but does lead to statistically significant, clinically relevant improvements in functional outcome and health-related quality of life that are sustained for at least 18 months. Funding UK Medical Research Council, Health Foundation UK, Stroke Association UK, Research Council of Norway, AFA Insurances Sweden, Swedish Heart Lung Fund, The Foundation of Marianne and Marcus Wallenberg, Polish Ministry of Science and Education, the Australian Heart Foundation, Australian National Health and Medical Research Council, Swiss National Research Foundation, Swiss Heart Foundation, Assessorato alla Sanita (Regione dell'Umbria, Italy), and Danube University. PMID:23791822

  7. Enceladus' Interior: A Liquid Circulation Model

    NASA Astrophysics Data System (ADS)

    Matson, Dennis L.; Johnson, Torrence; Lunine, Jonathan; Castillo-Rogez, Julie

    transferred to the near-surface ice. The water is now relatively cold and dense. It absorbs the remaining bubbles and descends via fractures or defects in the ice, and percolates down to the "ocean". The water is in intimate contact with the ice and chemical interactions and heat exchange are possible. While the formation of the briny "ocean" was envisioned as due to the exclusion of non-water chemical species from the ice as it froze [8], a number of mechanisms permit a variety of organic and inorganic species to be present in the ice. The downward percolation of briny water facilitates these by making a large volume of the ice accessible along the crack surfaces. References: [1] J. H. Waite Jr et al., Nature, 460, 487-490 (2009). [2] F. Postberg et al., Nature, 459, 1098-1101 (2009). [3] S. W. Kieffer et al., Science, 314, 1764-1766 (2006). [4] C. Howett, J. R. Spencer, J. Pearl, M. Segura, Bull. Am. Astron. Soc., 41, 1122 (2009). [5] O. Abramov, J. R. Spencer, Icarus, 199, 189-196 (2009). [6] G. D. Crawford, D. J. Stevenson, Icarus, 73, 66-79 (1988). [7] S. L. Murchie, J. W. Head, LPS XVII, 583-584 (1986). [8] M. Y. Zolotov, Geophysical Research Letters, 34, L23203 (2007). This work has been conducted at the Jet Propulsion Laboratory, California Institute of Technology under a contract with the National Aeronautics and Space Administration, and for JIL under the program "Incentivazione alla mobilita' di studiosi straineri italiani residenti all'estero" of Italy.

  8. PREFACE: DICE 2006—Quantum Mechanics between Decoherence and Determinism

    NASA Astrophysics Data System (ADS)

    Diósi, Lajos; Elze, Hans-Thomas; Vitiello, Giuseppe

    2007-06-01

    and sponsors generously supported the workshop and their representatives and, in particular, the citizens of Piombino are deeply thanked for the hospitality: G. Anselmi (Sindaco del Comune di Piombino), O. Dell'Omodarme (Assessore alle Culture), A. Tempestini (Assessore alla Pubblica Istruzione), E. Murzi (Assessore al Turismo), A. Falchi (Dirigente dei Servizi Educativi e Culturali), M. Gianfranchi (Responsabile del Servizio Promozione Culturale), T. Ghini (Ufficio Beni Culturali), and L. Grilli, C. Boggero and P. Venturi (Ufficio Cultura), M. Pierulivo (Segreteria del Sindaco), L. Pasquinucci (URP e Comunicazione). Thanks go to Idearte (Cooperativa di Servizi Culturali) and especially to L. Pesce (Vitrium Galleria, Populonia). Funds made available by Universitá di Pisa (Centro Interdisciplinare per lo Studio dei Sistemi Complessi -- CISSC and Domus Galilaeana) and Universitá di Salerno (Dipartimento di Fisica and INFN) are gratefully acknowledged. The research papers presented at the workshop, often incorporating further developments since then, have been edited by L. Diósi, H.-T. Elze and G. Vitiello. They are collected here, essentially following the program of the workshop, however, divided into Invited Lectures and Contributed Papers, respectively. In the name of all participants, we would like to thank G. Douglas (IOP Publishing, Bristol) for his friendly advice and immediate help during the editing process. Lajos Diósi, Hans-Thomas Elze and Giuseppe Vitiello Budapest, Pisa, Salerno, March 2007 1Decoherence and Entropy in Complex Systems ed H-T Elze Lecture Notes in Physics 633 (Berlin: Springer, 2004) 2Proceedings of the Second International Workshop on Decoherence, Information, Complexity and Entropy DICE 2004 ed H-T Elze Braz. J. Phys. 35, 2A and 2B (2005) pp 205 529 freely accessible at: www.sbfisica.org.br/bjp

  9. Editorial . Quantum fluctuations and coherence in optical and atomic structures

    NASA Astrophysics Data System (ADS)

    Eschner, Jürgen; Gatti, Alessandra; Maître, Agnès; Morigi, Giovanna

    2003-03-01

    the quantum level leads naturally to the issue of entanglement. This is an exclusive feature of the quantum world, which represents a valuable resource for quantum information processing and for high-precision measurements. The de.nition and criteria for measuring entanglement have been traditionally formulated within the Hilbert-space formalism (the quantum state formalism). However, quantum structures are intrinsically multi-mode systems, for which the Hilbert-space approach is often unpractical and cumbersome. More appealing are the "classical looking" phase space descriptions, where it is hence of great importance to reformulate concepts such as entanglement or Bell inequalities. The paper by Santos addresses the general problem of characterizing the entanglement properties of an electromagnetic field in the language of Q-representation. Entanglement involving the spatial modes of the electromagnetic field carrying orbital angular momentum provides new degrees of freedom and could play an important role in the field of quantum information, since such non-classical states enable the possibility of multichannel communications. The paper by Barbosa discusses quantum states of twin photons produced by parametric down-conversion and entangled in polarization and orbital angular momentum. The issue of entanglement is intrinsically connected to decoherence, and to the transition from the quantum to the classical world. In particular, massive systems are characterized by strong interactions with the environment, and at room temperature they usually exhibit classical behaviour. In this context, the paper by Karlsson discusses the decay of quantum correlations of protons and positive muons in condensed matter, a system characterized by strong coupling to the environment, and proposes experiments where such quantum correlations could be measured. Mancini et al. investigate macroscopic manifestations of quantum features, presenting a proposal for entangling the macroscopic

  10. 3D modelling of the Austroalpine-Penninic collisional wedge of the NW Alps: dataset management and preliminary results

    NASA Astrophysics Data System (ADS)

    Monopoli, Bruno; Bistacchi, Andrea; Bertolo, Davide; Dal Piaz, Giovanni; Gouffon, Yves; Massironi, Matteo; Sartori, Mario; Vittorio Dal Piaz, Giorgio

    2016-04-01

    considered as a sort of pseudo-stratigraphy, since they are the oldest feature that can be traced continuously at the map scale. For this reason we have developed a set of attributes identifying the tectonic and lithological units (a "legend"), implemented both in the GIS database and in the 3D models, which at the same time is compatible with the data structure of 3D modelling packages like Move and Skua/Gocad, and allows tracing the complex hierarchic classification of the units mapped in the GIS. This allows for the almost automatic and consistent two-way transfer of data between the GIS and geomodelling environments. E.g. results of 3D modelling, which is based on input data originally stored in the GIS, will eventually be transferred back to the GIS. The results of this study, which are preliminarily presented here, will open new opportunities to study the collision- and subduction-related nappe architecture and kinematics with younger deformations removed, and will eventually lead (with additional studies) to a step-by-step retrodeformation supported by modern technologies, following the path traced by Argand at the beginning of the 20th century. Argand E. 1909. L'exploration géologique des Alpes pennines centrales. Bull. Soc. Vaudoise Sci. Nat., 45, 217-276. Argand A. 1911. Les nappes de recouvrement des Alpes pennines et leurs prolongements structuraux. Mat. Carte Géol. Suisse, 31, 25. Argand A. 1916. Sur l'arc des Alpes occidentales. Eclogae Geol. Helv., 14, 145-191. Franchi S., Mattirolo E., Novarese V., Stella A. & Zaccagna D. 1908. Carta geologica delle Alpi Occidentali alla scala 1:400.000. Regio Ufficio Geologico, Roma. Gerlach H. 1869. Die Penninischen Alpen. N. Denkschr. Schweiz. Natf. Ges., 23, 132. Gerlach H. 1871. Das Suedwestliche Wallis. Beitraege Geol. Karte Schweiz, 9, 175. Giordano F. 1869. Sulla orografia e sulla geologica costituzione del Gran Cervino. Atti R. Acc. Sci. Torino, 4, 304-321.

  11. Geomorpho-Landscapes

    NASA Astrophysics Data System (ADS)

    Farabollini, Piero; Lugeri, Francesca; Amadio, Vittorio

    2014-05-01

    value -referring to biodiversity, geodiversity, culture- which can be considered as a special heritage. Starting from the concept of Geomorphosite, a geomorphologic landform with a scientific, cultural and socio-economical value (Panizza 2001), we propose a further definition, useful in the preliminary steps of the landscape analysis: "geomorpho-landscape" as a spatial object or component of a geological landscape, whose geo-morphological evolution, linked to the geological setting, are elements of aesthetical, semiological as well as historical and cultural value. The structure of the landscape is represented by the physical shape and spatial organization, in dynamic way: it is necessary to provide a readout of the landscape components that supplements the geo-morphological, lithological, geodiversity data (Lugeri et alii, 2012). The concept of "geomorpho-landscape" is conceived to address the need to describe by a synthetic approach the geological processes emerging at the landscape scale, allowing to link spatial patterns to geological processes Each geo-form has in itself geological, geo-morphological, landmark, historical and cultural features, of such special relevance, that they can be defined in terms of scientific quality, rarity, aesthetic appeal and educational and cultural value. Reference List AMADIO V. (2003). Analisi di sistemi e progetti di paesaggio. Franco Angeli, Milano, pp 236 AMADIO V, AMADEI M, BAGNAIA R, DI BUCCI D, LAURETI L, LISI A, LUGERI FR, LUGERI N. (2002). The role of Geomorphology in Landscape Ecology: The Landscape Unit Map of Italy', Scale 1: 250,000 ("Carta della Natura" Project). In: Allison RJ (ed) Applied Geomorphology: theory and practice. John Wiley & Sons, London, pp 265-282 APAT (2003). Carta della natura alla scala 1:250,000: metodologie di realizzazione. APAT, Manuali e linee guida 17/2003, Roma, pp 103 LUGERI F.R., FARABOLLINI P., GRAVIANO G. & AMADIO V. (2012). Geoheritage: Nature and culture in a landscape approach. European

  12. AAS 227: Day 1

    NASA Astrophysics Data System (ADS)

    Kohler, Susanna

    2016-01-01

    Editors Note:This week were at the 227th AAS Meeting in Kissimmee, FL. Along with several fellow authors from astrobites.com, I will bewritingupdates on selectedevents at themeeting and posting at the end of each day. Follow along here or at astrobites.com, or catch ourlive-tweeted updates from the @astrobites Twitter account. The usual posting schedule for AAS Nova will resumenext week.Things kicked off last night at our undergraduate reception booth. Thanks to all of you who stopped by we were delightedto have so many people tell us that they already know about and useastrobites, and we were excited to introduce a new cohort of students at AAS to astrobites for the first time.Tuesday morning was the official start of the meeting. Here are just a few of the talks and workshops astrobiters attended today.Opening Address (by Becky Smethurst)The President of the AAS, aka our fearless leader Meg Urry kicked off the meeting this morning at the purely coffee powered hour of 8am this morning. She spoke about the importance of young astronomers at the meeting (heres looking at you reader!) and also the importance of the new Working Group for Accessibility and Disabilities (aka WGAD pronounced like wicked) at the AAS. The Society has made extra effort this year to make the conference accessible to all,a message which was very well received by everyone in attendance.Kavli Lecture: New Horizons Alan Stern (by Becky Smethurst)We were definitely spoilt with the first Plenary lecture at this years conference Alan Stern gave us a a review of the New Horizons mission of the Pluto Fly By (astrobites covered the mission back in July with this post). We were treated to beautiful images, wonderful results and a foray into geology.Before (Hubble) and after #NewHorizons. #thatisall #science #astro alanstern #aas227 pic.twitter.com/kkMt6RsSIR Science News (@topsciencething) January 5, 2016Some awesome facts from the lecture that blew my mind:New Horizons is now 2AU (!) beyond Pluto

  13. VIMOS - a Cosmology Machine for the VLT

    NASA Astrophysics Data System (ADS)

    2002-03-01

    bundle can simultaneously observe a continuous sky area measuring no less than 56 x 56 arcsec 2. A dedicated machine, the Mask Manufacturing Unit (MMU) , cuts the slits for the entrance apertures of the spectrograph. The laser is capable of cutting 200 slits in less than 15 minutes. This facility was put into operation at Paranal by the VIRMOS Consortium already in August 2000 and has since been extensively used for observations with the FORS2 instrument; more details are available in ESO PR 19/99. Fast start-up of VIMOS at Paranal ESO PR Photo 09d/02 ESO PR Photo 09d/02 [Preview - JPEG: 473 x 400 pix - 280k] [Normal - JPEG: 946 x 1209 pix - 728k] ESO PR Photo 09e/02 ESO PR Photo 09e/02 [Preview - JPEG: 400 x 438 pix - 176k] [Normal - JPEG: 800 x 876 pix - 664k] Caption : PR Photo 09d/02 : The VIRMOS team in the MELIPAL control room, moments after "First Light" on February 26, 2002. From left to right: Oreste Caputi, Marco Scodeggio, Giovanni Sciarretta , Olivier Le Fevre, Sylvie Brau-Nogue, Christian Lucuix, Bianca Garilli, Markus Kissler-Patig (in front), Xavier Reyes, Michel Saisse, Luc Arnold and Guido Mancini . PR Photo 09e/02 : The spiral galaxy NGC 5364 was the first object to be observed by VIMOS. This false-colour near-infrared, raw "First Light" photo shows the extensive spiral arms. Technical information about this photo is available below. VIMOS was shipped from Observatoire de Haute-Provence (France) at the end of 2001, and reassembled at Paranal during a first period in January 2002. From mid-February, the instrument was made ready for installation on the VLT MELIPAL telescope; this happened on February 24, 2002. VIMOS saw "First Light" just two days later, on February 26, 2000, cf. PR Photo 09e/02 . During the same night, a number of excellent images were obtained of various objects, demonstrating the fine capabilities of the instrument in the "direct imaging"-mode. The first spectra were successfully taken during the night of March 2 - 3, 2002 . The slit

  14. AAS 227: Day 1

    NASA Astrophysics Data System (ADS)

    Kohler, Susanna

    2016-01-01

    Editors Note:This week were at the 227th AAS Meeting in Kissimmee, FL. Along with several fellow authors from astrobites.com, I will bewritingupdates on selectedevents at themeeting and posting at the end of each day. Follow along here or at astrobites.com, or catch ourlive-tweeted updates from the @astrobites Twitter account. The usual posting schedule for AAS Nova will resumenext week.Things kicked off last night at our undergraduate reception booth. Thanks to all of you who stopped by we were delightedto have so many people tell us that they already know about and useastrobites, and we were excited to introduce a new cohort of students at AAS to astrobites for the first time.Tuesday morning was the official start of the meeting. Here are just a few of the talks and workshops astrobiters attended today.Opening Address (by Becky Smethurst)The President of the AAS, aka our fearless leader Meg Urry kicked off the meeting this morning at the purely coffee powered hour of 8am this morning. She spoke about the importance of young astronomers at the meeting (heres looking at you reader!) and also the importance of the new Working Group for Accessibility and Disabilities (aka WGAD pronounced like wicked) at the AAS. The Society has made extra effort this year to make the conference accessible to all,a message which was very well received by everyone in attendance.Kavli Lecture: New Horizons Alan Stern (by Becky Smethurst)We were definitely spoilt with the first Plenary lecture at this years conference Alan Stern gave us a a review of the New Horizons mission of the Pluto Fly By (astrobites covered the mission back in July with this post). We were treated to beautiful images, wonderful results and a foray into geology.Before (Hubble) and after #NewHorizons. #thatisall #science #astro alanstern #aas227 pic.twitter.com/kkMt6RsSIR Science News (@topsciencething) January 5, 2016Some awesome facts from the lecture that blew my mind:New Horizons is now 2AU (!) beyond Pluto