Sample records for j-j heisenberg model

  1. Multipartite quantum correlations in the extended J1-J2 Heisenberg model

    NASA Astrophysics Data System (ADS)

    Batle, J.; Tarawneh, O.; Nagata, Koji; Nakamura, Tadao; Abdalla, S.; Farouk, Ahmed

    2017-11-01

    Multipartite entanglement and the maximum violation of Bell inequalities are studied in finite clusters of spins in an extended J1-J2 Heisenberg model at zero temperature. The ensuing highly frustrated states will unveil a rich structure for different values of the corresponding spin-spin interaction strengths. The interplay between nearest-neighbors, next-nearest neighbors and further couplings will be explored using multipartite correlations. The model is relevant to certain quantum annealing computation architectures where an all-to-all connectivity is considered.

  2. Dynamical structure factor of the J1-J2 Heisenberg model in one dimension: The variational Monte Carlo approach

    NASA Astrophysics Data System (ADS)

    Ferrari, Francesco; Parola, Alberto; Sorella, Sandro; Becca, Federico

    2018-06-01

    The dynamical spin structure factor is computed within a variational framework to study the one-dimensional J1-J2 Heisenberg model. Starting from Gutzwiller-projected fermionic wave functions, the low-energy spectrum is constructed from two-spinon excitations. The direct comparison with Lanczos calculations on small clusters demonstrates the excellent description of both gapless and gapped (dimerized) phases, including incommensurate structures for J2/J1>0.5 . Calculations on large clusters show how the intensity evolves when increasing the frustrating ratio and give an unprecedented accurate characterization of the dynamical properties of (nonintegrable) frustrated spin models.

  3. U (1 ) -symmetric infinite projected entangled-pair states study of the spin-1/2 square J1-J2 Heisenberg model

    NASA Astrophysics Data System (ADS)

    Haghshenas, R.; Sheng, D. N.

    2018-05-01

    We develop an improved variant of U (1 ) -symmetric infinite projected entangled-pair states (iPEPS) ansatz to investigate the ground-state phase diagram of the spin-1 /2 square J1-J2 Heisenberg model. In order to improve the accuracy of the ansatz, we discuss a simple strategy to select automatically relevant symmetric sectors and also introduce an optimization method to treat second-neighbor interactions more efficiently. We show that variational ground-state energies of the model obtained by the U (1 ) -symmetric iPEPS ansatz (for a fixed bond dimension D ) set a better upper bound, improving previous tensor-network-based results. By studying the finite-D scaling of the magnetically order parameter, we find a Néel phase for J2/J1<0.53 . For 0.53 <J2/J1<0.61 , a nonmagnetic columnar valence bond solid (VBS) state is established as observed by the pattern of local bond energy. The divergent behavior of correlation length ξ ˜D1.2 and vanishing order parameters are consistent with a deconfined Néel-to-VBS transition at J2c1/J1=0.530 (5 ) , where estimated critical anomalous exponents are ηs˜0.6 and ηd˜1.9 for spin and dimer correlations, respectively. We show that the associated VBS order parameter monotonically increases with J2/J1 and finally a first-order quantum phase transition takes place at J2c2/J1=0.610 (2 ) to the conventional Stripe phase. We compare our results with earlier DMRG and PEPS studies and suggest future directions for resolving remaining issues.

  4. Modified spin-wave theory with ordering vector optimization: spatially anisotropic triangular lattice and J1J2J3 model with Heisenberg interactions

    NASA Astrophysics Data System (ADS)

    Hauke, Philipp; Roscilde, Tommaso; Murg, Valentin; Cirac, J. Ignacio; Schmied, Roman

    2011-07-01

    We study the ground-state phases of the S=1/2 Heisenberg quantum antiferromagnet on the spatially anisotropic triangular lattice (SATL) and on the square lattice with up to next-next-nearest-neighbor coupling (the J1J2J3 model), making use of Takahashi's modified spin-wave (MSW) theory supplemented by ordering vector optimization. We compare the MSW results with exact diagonalization and projected-entangled-pair-states calculations, demonstrating their qualitative and quantitative reliability. We find that the MSW theory correctly accounts for strong quantum effects on the ordering vector of the magnetic phases of the models under investigation: in particular, collinear magnetic order is promoted at the expense of non-collinear (spiral) order, and several spiral states that are stable at the classical level disappear from the quantum phase diagram. Moreover, collinear states and non-collinear ones are never connected continuously, but they are separated by parameter regions in which the MSW theory breaks down, signaling the possible appearance of a non-magnetic ground state. In the case of the SATL, a large breakdown region appears also for weak couplings between the chains composing the lattice, suggesting the possible occurrence of a large non-magnetic region continuously connected with the spin-liquid state of the uncoupled chains. This shows that the MSW theory is—despite its apparent simplicity—a versatile tool for finding candidate regions in the case of spin-liquid phases, which are among prime targets for relevant quantum simulations.

  5. Hierarchical mean-field approach to the J1-J2 Heisenberg model on a square lattice

    NASA Astrophysics Data System (ADS)

    Isaev, L.; Ortiz, G.; Dukelsky, J.

    2009-01-01

    We study the quantum phase diagram and excitation spectrum of the frustrated J1-J2 spin-1/2 Heisenberg Hamiltonian. A hierarchical mean-field approach, at the heart of which lies the idea of identifying relevant degrees of freedom, is developed. Thus, by performing educated, manifestly symmetry-preserving mean-field approximations, we unveil fundamental properties of the system. We then compare various coverings of the square lattice with plaquettes, dimers, and other degrees of freedom, and show that only the symmetric plaquette covering, which reproduces the original Bravais lattice, leads to the known phase diagram. The intermediate quantum paramagnetic phase is shown to be a (singlet) plaquette crystal, connected with the neighboring Néel phase by a continuous phase transition. We also introduce fluctuations around the hierarchical mean-field solutions, and demonstrate that in the paramagnetic phase the ground and first excited states are separated by a finite gap, which closes in the Néel and columnar phases. Our results suggest that the quantum phase transition between Néel and paramagnetic phases can be properly described within the Ginzburg-Landau-Wilson paradigm.

  6. Hierarchical mean-field approach to the J1-J2 Heisenberg model on a square lattice

    NASA Astrophysics Data System (ADS)

    Isaev, Leonid; Ortiz, Gerardo; Dukelsky, Jorge

    2009-03-01

    We study the quantum phase diagram and excitation spectrum of the frustrated J1-J2 spin-1/2 Heisenberg Hamiltonian. A hierarchical mean-field approach, at the heart of which lies the idea of identifying relevant degrees of freedom, is developed. Thus, by performing educated, manifestly symmetry preserving mean-field approximations, we unveil fundamental properties of the system. We then compare various coverings of the square lattice with plaquettes, dimers and other degrees of freedom, and show that only the symmetric plaquette covering, which reproduces the original Bravais lattice, leads to the known phase diagram. The intermediate quantum paramagnetic phase is shown to be a (singlet) plaquette crystal, connected with the neighbouring N'eel phase by a continuous phase transition. We also introduce fluctuations around the hierarchical mean-field solutions, and demonstrate that in the paramagnetic phase the ground and first excited states are separated by a finite gap, which closes in the N'eel and columnar phases. Our results suggest that the quantum phase transition between N'eel and paramagnetic phases can be properly described within the Ginzburg-Landau-Wilson paradigm.

  7. Ground-state ordering of the J1-J2 model on the simple cubic and body-centered cubic lattices

    NASA Astrophysics Data System (ADS)

    Farnell, D. J. J.; Götze, O.; Richter, J.

    2016-06-01

    The J1-J2 Heisenberg model is a "canonical" model in the field of quantum magnetism in order to study the interplay between frustration and quantum fluctuations as well as quantum phase transitions driven by frustration. Here we apply the coupled cluster method (CCM) to study the spin-half J1-J2 model with antiferromagnetic nearest-neighbor bonds J1>0 and next-nearest-neighbor bonds J2>0 for the simple cubic (sc) and body-centered cubic (bcc) lattices. In particular, we wish to study the ground-state ordering of these systems as a function of the frustration parameter p =z2J2/z1J1 , where z1 (z2) is the number of nearest (next-nearest) neighbors. We wish to determine the positions of the phase transitions using the CCM and we aim to resolve the nature of the phase transition points. We consider the ground-state energy, order parameters, spin-spin correlation functions, as well as the spin stiffness in order to determine the ground-state phase diagrams of these models. We find a direct first-order phase transition at a value of p =0.528 from a state of nearest-neighbor Néel order to next-nearest-neighbor Néel order for the bcc lattice. For the sc lattice the situation is more subtle. CCM results for the energy, the order parameter, the spin-spin correlation functions, and the spin stiffness indicate that there is no direct first-order transition between ground-state phases with magnetic long-range order, rather it is more likely that two phases with antiferromagnetic long range are separated by a narrow region of a spin-liquid-like quantum phase around p =0.55 . Thus the strong frustration present in the J1-J2 Heisenberg model on the sc lattice may open a window for an unconventional quantum ground state in this three-dimensional spin model.

  8. Quantum phase diagram of distorted J 1 - J 2 Heisenberg S  =  1/2 antiferromagnet in honeycomb lattice: a modified spin wave study

    NASA Astrophysics Data System (ADS)

    Ghorbani, Elaheh; Shahbazi, Farhad; Mosadeq, Hamid

    2016-10-01

    Using the modified spin wave method, we study the {{J}1}-{{J}2} Heisenberg model with first and second neighbor antiferromagnetic exchange interactions. For a symmetric S  =  1/2 model, with the same couplings for all the equivalent neighbors, we find three phases in terms of the frustration parameter \\barα={{J}2}/{{J}1} : (1) a commensurate collinear ordering with staggered magnetization (Néel.I state) for 0≤slant \\barα≲ 0.207 , (2) a magnetically gapped disordered state for 0.207≲ \\barα≲ 0.369 , preserving all the symmetries of the Hamiltonian and lattice, which by definition is a quantum spin liquid (QSL) state and (3) a commensurate collinear ordering in which two out of the three nearest neighbor magnetizations are antiparallel and the remaining pair are parallel (Néel.II state), for 0.396≲ \\barα≤slant 1 . We also explore the phase diagram of a distorted {{J}1}-{{J}2} model with S  =  1/2. Distortion is introduced as an inequality of one nearest neighbor coupling with the other two. This yields a richer phase diagram by the appearance of a new gapped QSL, a gapless QSL and also a valence bond crystal phase in addition to the previous three phases found for the undistorted model.

  9. Ground-state phases of the spin-1 J1-J2 Heisenberg antiferromagnet on the honeycomb lattice

    NASA Astrophysics Data System (ADS)

    Li, P. H. Y.; Bishop, R. F.

    2016-06-01

    We study the zero-temperature quantum phase diagram of a spin-1 Heisenberg antiferromagnet on the honeycomb lattice with both nearest-neighbor exchange coupling J1>0 and frustrating next-nearest-neighbor coupling J2≡κ J1>0 , using the coupled cluster method implemented to high orders of approximation, and based on model states with different forms of classical magnetic order. For each we calculate directly in the bulk thermodynamic limit both ground-state low-energy parameters (including the energy per spin, magnetic order parameter, spin stiffness coefficient, and zero-field uniform transverse magnetic susceptibility) and their generalized susceptibilities to various forms of valence-bond crystalline (VBC) order, as well as the energy gap to the lowest-lying spin-triplet excitation. In the range 0 <κ <1 we find evidence for four distinct phases. Two of these are quasiclassical phases with antiferromagnetic long-range order, one with two-sublattice Néel order for κ <κc1=0.250(5 ) , and another with four-sublattice Néel-II order for κ >κc 2=0.340 (5 ) . Two different paramagnetic phases are found to exist in the intermediate region. Over the range κc1<κ<κci=0.305 (5 ) we find a gapless phase with no discernible magnetic order, which is a strong candidate for being a quantum spin liquid, while over the range κci<κ <κc 2 we find a gapped phase, which is most likely a lattice nematic with staggered dimer VBC order that breaks the lattice rotational symmetry.

  10. Strong anisotropy within a Heisenberg model in the J eff = 1 2 insulating state of Sr 2 Ir 0.8 Ru 0.2 O 4

    DOE PAGES

    Calder, Stuart A.; Kim, J. W.; Taylor, Alice E.; ...

    2016-12-28

    The dispersive magnetic excitations in Sr 2IrO 4 have previously been well described within an isospin-1/2 Heisenberg model on a square lattice that revealed parallels with La 2CuO 4. In this paper, we investigate the inelastic spectra of Sr 2Ir 0.8Ru 0.2O 4 with resonant inelastic x-ray scattering (RIXS) at the Ir L 3 edge. The results are well described using linear spin-wave theory within a similar Heisenberg model applicable to Sr 2IrO 4; however, the disorder induced by the substitution of 20% Ir 4+ ions for Ru 4+ removes longer range exchange interactions. A large spin gap (40 meV)more » is measured indicating strong anisotropy from spin-orbit coupling that is manifest due to the altered magnetic structure in Sr 2Ir 0.8Ru 0.2O 4 with c-axis aligned moments compared to the basal plane moments in the parent. Finally, collectively the results indicate the robustness of a Heisenberg model description even when the magnetic structure is altered and the J eff = 1/2 moments are diluted.« less

  11. Heisenberg necklace model in a magnetic field

    DOE PAGES

    Tsvelik, A. M.; Zaliznyak, I. A.

    2016-08-26

    Here, we study the low-energy sector of the Heisenberg necklace model. Using the field-theory methods, we estimate how the coupling of the electronic spins with the paramagnetic Kondo spins affects the overall spin dynamics and evaluate its dependence on a magnetic field. We are motivated by the experimental realizations of the spin-1/2 Heisenberg chains in SrCuO 2 and Sr 2CuO 3 cuprates, which remain one-dimensional Luttinger liquids down to temperatures much lower than the in-chain exchange coupling J. We also consider the perturbation of the energy spectrum caused by the interaction γ with nuclear spins (I=3/2) present on the samemore » sites. We find that the resulting necklace model has a characteristic energy scale, Λ~J 1/3(γI) 2/3, at which the coupling between (nuclear) spins of the necklace and the spins of the Heisenberg chain becomes strong. Furthermore, this energy scale is insensitive to a magnetic field B. For μBB>Λ we find two gapless bosonic modes that have different velocities, whose ratio at strong fields approaches a universal number, 2√+1.« less

  12. Exact expression of the t-J model in terms of local spin and fermionic holon operators

    NASA Astrophysics Data System (ADS)

    Wang, Y. R.; Rice, M. J.

    1994-02-01

    An exact expression for the Hamiltonian H of the t-J model in terms of local spin (Si) and fermionic holon (ei) operators is derived which requires no constraint between these operators. The result for the Hamiltonian H is H=-t tsumijeie°j(1/2+2Si.Sj)+(J/2)t smij(1-e°iei)(Si.Sj-1/4)(1-e°je The number of electrons at site i is given by ni=1-e°iei, and the true spin operator S~i, is related to the local spin operator by S~i=(1-e°iei)Si. The expression correctly produces the Nagaoka theorem in the limit J-->0, and preserves the time-reversal symmetry of the original model. For a bipartite lattice, H describes a competition between ferromagnetism, favored by the hopping term, and antiferromagnetism, favored by the Heisenberg term.

  13. A tensor product state approach to spin-1/2 square J1-J2 antiferromagnetic Heisenberg model: evidence for deconfined quantum criticality

    NASA Astrophysics Data System (ADS)

    Wang, Ling; Gu, Zheng-Cheng; Verstraete, Frank; Wen, Xiang-Gang

    We study this model using the cluster update algorithm for tensor product states (TPSs). We find that the ground state energies at finite sizes and in the thermodynamic limit are in good agreement with the exact diagonalization study. At the largest bond dimension available D = 9 and through finite size scaling of the magnetization order near the transition point, we accurately determine the critical point J2c1 = 0 . 53 (1) J1 and the critical exponents β = 0 . 50 (4) . In the intermediate region we find a paramagnetic ground state without any static valence bond solid (VBS) order, supported by an exponentially decaying spin-spin correlation while a power law decaying dimer-dimer correlation. By fitting a universal scaling function for the spin-spin correlation we find the critical exponents ν = 0 . 68 (3) and ηs = 0 . 34 (6) , which is very close to the observed critical exponents for deconfined quantum critical point (DQCP) in other systems. Thus our numerical results strongly suggest a Landau forbidden phase transition from Neel order to VBS order at J2c1 = 0 . 53 (1) J1 . This project is supported by the EU Strep project QUEVADIS, the ERC Grant QUERG, and the FWF SFB Grants FoQuS and ViCoM; and the Institute for Quantum Information and Matter.

  14. Ultracold few fermionic atoms in needle-shaped double wells: spin chains and resonating spin clusters from microscopic Hamiltonians emulated via antiferromagnetic Heisenberg and t-J models

    NASA Astrophysics Data System (ADS)

    Yannouleas, Constantine; Brandt, Benedikt B.; Landman, Uzi

    2016-07-01

    Advances with trapped ultracold atoms intensified interest in simulating complex physical phenomena, including quantum magnetism and transitions from itinerant to non-itinerant behavior. Here we show formation of antiferromagnetic ground states of few ultracold fermionic atoms in single and double well (DW) traps, through microscopic Hamiltonian exact diagonalization for two DW arrangements: (i) two linearly oriented one-dimensional, 1D, wells, and (ii) two coupled parallel wells, forming a trap of two-dimensional, 2D, nature. The spectra and spin-resolved conditional probabilities reveal for both cases, under strong repulsion, atomic spatial localization at extemporaneously created sites, forming quantum molecular magnetic structures with non-itinerant character. These findings usher future theoretical and experimental explorations into the highly correlated behavior of ultracold strongly repelling fermionic atoms in higher dimensions, beyond the fermionization physics that is strictly applicable only in the 1D case. The results for four atoms are well described with finite Heisenberg spin-chain and cluster models. The numerical simulations of three fermionic atoms in symmetric DWs reveal the emergent appearance of coupled resonating 2D Heisenberg clusters, whose emulation requires the use of a t-J-like model, akin to that used in investigations of high T c superconductivity. The highly entangled states discovered in the microscopic and model calculations of controllably detuned, asymmetric, DWs suggest three-cold-atom DW quantum computing qubits.

  15. Spinon excitation spectra of the J1-J2 chain from analytical calculations in the dimer basis and exact diagonalization

    NASA Astrophysics Data System (ADS)

    Lavarélo, Arthur; Roux, Guillaume

    2014-10-01

    The excitation spectrum of the frustrated spin-1/2 Heisenberg chain is reexamined using variational and exact diagonalization calculations. We show that the overlap matrix of the short-range resonating valence bond states basis can be inverted which yields tractable equations for single and two spinons excitations. Older results are recovered and new ones, such as the bond-state dispersion relation and its size with momentum at the Majumdar-Ghosh point are found. In particular, this approach yields a gap opening at J 2 = 0.25 J 1 and an onset of incommensurability in the dispersion relation at J 2 = 9/17 J 1 as in [S. Brehmer et al., J. Phys.: Condens. Matter 10, 1103 (1998)]. These analytical results provide a good support for the understanding of exact diagonalization spectra, assuming an independent spinons picture.

  16. Renormalization group analysis of dipolar Heisenberg model on square lattice

    NASA Astrophysics Data System (ADS)

    Keleş, Ahmet; Zhao, Erhai

    2018-06-01

    We present a detailed functional renormalization group analysis of spin-1/2 dipolar Heisenberg model on square lattice. This model is similar to the well-known J1-J2 model and describes the pseudospin degrees of freedom of polar molecules confined in deep optical lattice with long-range anisotropic dipole-dipole interactions. Previous study of this model based on tensor network ansatz indicates a paramagnetic ground state for certain dipole tilting angles which can be tuned in experiments to control the exchange couplings. The tensor ansatz formulated on a small cluster unit cell is inadequate to describe the spiral order, and therefore the phase diagram at high azimuthal tilting angles remains undetermined. Here, we obtain the full phase diagram of the model from numerical pseudofermion functional renormalization group calculations. We show that an extended quantum paramagnetic phase is realized between the Néel and stripe/spiral phases. In this region, the spin susceptibility flows smoothly down to the lowest numerical renormalization group scales with no sign of divergence or breakdown of the flow, in sharp contrast to the flow towards the long-range-ordered phases. Our results provide further evidence that the dipolar Heisenberg model is a fertile ground for quantum spin liquids.

  17. Incommensurate phase of a triangular frustrated Heisenberg model studied via Schwinger-boson mean-field theory

    NASA Astrophysics Data System (ADS)

    Li, Peng; Su, Haibin; Dong, Hui-Ning; Shen, Shun-Qing

    2009-08-01

    We study a triangular frustrated antiferromagnetic Heisenberg model with nearest-neighbor interactions J1 and third-nearest-neighbor interactions J3 by means of Schwinger-boson mean-field theory. By setting an antiferromagnetic J3 and varying J1 from positive to negative values, we disclose the low-temperature features of its interesting incommensurate phase. The gapless dispersion of quasiparticles leads to the intrinsic T2 law of specific heat. The magnetic susceptibility is linear in temperature. The local magnetization is significantly reduced by quantum fluctuations. We address possible relevance of these results to the low-temperature properties of NiGa2S4. From a careful analysis of the incommensurate spin wavevector, the interaction parameters are estimated as J1≈-3.8755 K and J3≈14.0628 K, in order to account for the experimental data.

  18. Fermionology in the Kondo-Heisenberg model: the case of CeCoIn5

    NASA Astrophysics Data System (ADS)

    Zhong, Yin; Zhang, Lan; Lu, Han-Tao; Luo, Hong-Gang

    2015-09-01

    The Fermi surface of heavy electron systems plays a fundamental role in understanding their variety of puzzling phenomena, for example, quantum criticality, strange metal behavior, unconventional superconductivity and even enigmatic phases with yet unknown order parameters. The spectroscopy measurement of the typical heavy fermion superconductor CeCoIn5 has demonstrated multi-Fermi surface structure, which has not been studied in detail theoretically in a model system like the Kondo-Heisenberg model. In this work, we take a step toward such a theoretical model by revisiting the Kondo-Heisenberg model. It is found that the usual self-consistent calculation cannot reproduce the fermionology of the experimental observation of the system due to the sign binding between the hopping of the conduction electrons and the mean-field valence-bond order. To overcome such inconsistency, the mean-field valence-bond order is considered as a free/fitting parameter to correlate them with real-life experiments as performed in recent experiments [M.P. Allan, F. Massee, D.K. Morr, J. Van Dyke, A.W. Rost, A.P. Mackenzie, C. Petrovic, J.C. Davis, Nat. Phys. 9, 468 (2013); J. Van Dyke, F. Massee, M.P. Allan, J.C. Davis, C. Petrovic, D.K. Morr, Proc. Natl. Acad. Sci. 111, 11663 (2014)], which also explicitly reflects the intrinsic dispersion of local electrons observed in experimental measurements. Given the fermionology, the calculated effective mass enhancement, entropy, superfluid density and Knight shift are all in qualitative agreement with the experimental results of CeCoIn5, which confirms our assumption. Our result supports a d_{x^2 - y^2 }-wave pairing structure in the heavy fermion material CeCoIn5.

  19. One dimensionalization in the spin-1 Heisenberg model on the anisotropic triangular lattice

    NASA Astrophysics Data System (ADS)

    Gonzalez, M. G.; Ghioldi, E. A.; Gazza, C. J.; Manuel, L. O.; Trumper, A. E.

    2017-11-01

    We investigate the effect of dimensional crossover in the ground state of the antiferromagnetic spin-1 Heisenberg model on the anisotropic triangular lattice that interpolates between the regime of weakly coupled Haldane chains (J'≪J ) and the isotropic triangular lattice (J'=J ). We use the density-matrix renormalization group (DMRG) and Schwinger boson theory performed at the Gaussian correction level above the saddle-point solution. Our DMRG results show an abrupt transition between decoupled spin chains and the spirally ordered regime at (J'/J) c˜0.42 , signaled by the sudden closing of the spin gap. Coming from the magnetically ordered side, the computation of the spin stiffness within Schwinger boson theory predicts the instability of the spiral magnetic order toward a magnetically disordered phase with one-dimensional features at (J'/J) c˜0.43 . The agreement of these complementary methods, along with the strong difference found between the intra- and the interchain DMRG short spin-spin correlations for sufficiently large values of the interchain coupling, suggests that the interplay between the quantum fluctuations and the dimensional crossover effects gives rise to the one-dimensionalization phenomenon in this frustrated spin-1 Hamiltonian.

  20. Role of quantum fluctuations on spin liquids and ordered phases in the Heisenberg model on the honeycomb lattice

    NASA Astrophysics Data System (ADS)

    Merino, Jaime; Ralko, Arnaud

    2018-05-01

    Motivated by the rich physics of honeycomb magnetic materials, we obtain the phase diagram and analyze magnetic properties of the spin-1 /2 and spin-1 J1-J2-J3 Heisenberg model on the honeycomb lattice. Based on the SU(2) and SU(3) symmetry representations of the Schwinger boson approach, which treats disordered spin liquids and magnetically ordered phases on an equal footing, we obtain the complete phase diagrams in the (J2,J3) plane. This is achieved using a fully unrestricted approach which does not assume any pre-defined Ansätze. For S =1 /2 , we find a quantum spin liquid (QSL) stabilized between the Néel, spiral, and collinear antiferromagnetic phases in agreement with previous theoretical work. However, by increasing S from 1 /2 to 1, the QSL is quickly destroyed due to the weakening of quantum fluctuations indicating that the model already behaves as a quasiclassical system. The dynamical structure factors and temperature dependence of the magnetic susceptibility are obtained in order to characterize all phases in the phase diagrams. Moreover, motivated by the relevance of the single-ion anisotropy, D , to various S =1 honeycomb compounds, we have analyzed the destruction of magnetic order based on an SU(3) representation of the Schwinger bosons. Our analysis provides a unified understanding of the magnetic properties of honeycomb materials realizing the J1-J2-J3 Heisenberg model from the strong quantum spin regime at S =1 /2 to the S =1 case. Neutron scattering and magnetic susceptibility experiments can be used to test the destruction of the QSL phase when replacing S =1 /2 by S =1 localized moments in certain honeycomb compounds.

  1. J1-J2 square lattice antiferromagnetism in the orbitally quenched insulator MoOPO4

    NASA Astrophysics Data System (ADS)

    Yang, L.; Jeong, M.; Babkevich, P.; Katukuri, V. M.; Náfrádi, B.; Shaik, N. E.; Magrez, A.; Berger, H.; Schefer, J.; Ressouche, E.; Kriener, M.; Živković, I.; Yazyev, O. V.; Forró, L.; Rønnow, H. M.

    2017-07-01

    We report magnetic and thermodynamic properties of a 4 d1 (Mo5 +) magnetic insulator MoOPO4 single crystal, which realizes a J1-J2 Heisenberg spin-1 /2 model on a stacked square lattice. The specific-heat measurements show a magnetic transition at 16 K which is also confirmed by magnetic susceptibility, ESR, and neutron diffraction measurements. Magnetic entropy deduced from the specific heat corresponds to a two-level degree of freedom per Mo5 + ion, and the effective moment from the susceptibility corresponds to the spin-only value. Using ab initio quantum chemistry calculations, we demonstrate that the Mo5 + ion hosts a purely spin-1 /2 magnetic moment, indicating negligible effects of spin-orbit interaction. The quenched orbital moments originate from the large displacement of Mo ions inside the MoO6 octahedra along the apical direction. The ground state is shown by neutron diffraction to support a collinear Néel-type magnetic order, and a spin-flop transition is observed around an applied magnetic field of 3.5 T. The magnetic phase diagram is reproduced by a mean-field calculation assuming a small easy-axis anisotropy in the exchange interactions. Our results suggest 4 d molybdates as an alternative playground to search for model quantum magnets.

  2. Entropic uncertainty relations in the Heisenberg XXZ model and its controlling via filtering operations

    NASA Astrophysics Data System (ADS)

    Ming, Fei; Wang, Dong; Shi, Wei-Nan; Huang, Ai-Jun; Sun, Wen-Yang; Ye, Liu

    2018-04-01

    The uncertainty principle is recognized as an elementary ingredient of quantum theory and sets up a significant bound to predict outcome of measurement for a couple of incompatible observables. In this work, we develop dynamical features of quantum memory-assisted entropic uncertainty relations (QMA-EUR) in a two-qubit Heisenberg XXZ spin chain with an inhomogeneous magnetic field. We specifically derive the dynamical evolutions of the entropic uncertainty with respect to the measurement in the Heisenberg XXZ model when spin A is initially correlated with quantum memory B. It has been found that the larger coupling strength J of the ferromagnetism ( J < 0 ) and the anti-ferromagnetism ( J > 0 ) chains can effectively degrade the measuring uncertainty. Besides, it turns out that the higher temperature can induce the inflation of the uncertainty because the thermal entanglement becomes relatively weak in this scenario, and there exists a distinct dynamical behavior of the uncertainty when an inhomogeneous magnetic field emerges. With the growing magnetic field | B | , the variation of the entropic uncertainty will be non-monotonic. Meanwhile, we compare several different optimized bounds existing with the initial bound proposed by Berta et al. and consequently conclude Adabi et al.'s result is optimal. Moreover, we also investigate the mixedness of the system of interest, dramatically associated with the uncertainty. Remarkably, we put forward a possible physical interpretation to explain the evolutionary phenomenon of the uncertainty. Finally, we take advantage of a local filtering operation to steer the magnitude of the uncertainty. Therefore, our explorations may shed light on the entropic uncertainty under the Heisenberg XXZ model and hence be of importance to quantum precision measurement over solid state-based quantum information processing.

  3. Phase diagram of the frustrated J 1 ‑ J 2 transverse field Ising model on the square lattice

    NASA Astrophysics Data System (ADS)

    Sadrzadeh, M.; Langari, A.

    2018-03-01

    We study the zero-temperature phase diagram of transverse field Ising model on the J 1 ‑ J 2 square lattice. In zero magnetic field, the model has a classical Néel phase for J 2/J 1 < 0.5 and an antiferromagnetic collinear phase for J 2/J 1 > 0.5. We incorporate harmonic fluctuations by using linear spin wave theory (LSWT) with single spin flip excitations above a magnetic order background and obtain the phase diagram of the model in this approximation. We find that harmonic quantum fluctuations of LSWT fail to lift the large degeneracy at J 2/J 1 = 0.5 and exhibit some inconsistent regions on the phase diagram. However, we show that anharmonic fluctuations of cluster operator approach (COA) resolve the inconsistency of the LSWT, which reveals a string-valence bond solid ordered phase for the highly frustrated region.

  4. A satellite relative motion model including J_2 and J_3 via Vinti's intermediary

    NASA Astrophysics Data System (ADS)

    Biria, Ashley D.; Russell, Ryan P.

    2018-03-01

    Vinti's potential is revisited for analytical propagation of the main satellite problem, this time in the context of relative motion. A particular version of Vinti's spheroidal method is chosen that is valid for arbitrary elliptical orbits, encapsulating J_2, J_3, and generally a partial J_4 in an orbit propagation theory without recourse to perturbation methods. As a child of Vinti's solution, the proposed relative motion model inherits these properties. Furthermore, the problem is solved in oblate spheroidal elements, leading to large regions of validity for the linearization approximation. After offering several enhancements to Vinti's solution, including boosts in accuracy and removal of some singularities, the proposed model is derived and subsequently reformulated so that Vinti's solution is piecewise differentiable. While the model is valid for the critical inclination and nonsingular in the element space, singularities remain in the linear transformation from Earth-centered inertial coordinates to spheroidal elements when the eccentricity is zero or for nearly equatorial orbits. The new state transition matrix is evaluated against numerical solutions including the J_2 through J_5 terms for a wide range of chief orbits and separation distances. The solution is also compared with side-by-side simulations of the original Gim-Alfriend state transition matrix, which considers the J_2 perturbation. Code for computing the resulting state transition matrix and associated reference frame and coordinate transformations is provided online as supplementary material.

  5. Model-Independent Evidence for J/ψp Contributions to Λ_{b}^{0}→J/ψpK^{-} Decays.

    PubMed

    Aaij, R; Abellán Beteta, C; Adeva, B; Adinolfi, M; Ajaltouni, Z; Akar, S; Albrecht, J; Alessio, F; Alexander, M; Ali, S; Alkhazov, G; Alvarez Cartelle, P; Alves, A A; Amato, S; Amerio, S; Amhis, Y; An, L; Anderlini, L; Andreassi, G; Andreotti, M; Andrews, J E; Appleby, R B; Aquines Gutierrez, O; Archilli, F; d'Argent, P; Artamonov, A; Artuso, M; Aslanides, E; Auriemma, G; Baalouch, M; Bachmann, S; Back, J J; Badalov, A; Baesso, C; Baker, S; Baldini, W; Barlow, R J; Barschel, C; Barsuk, S; Barter, W; Batozskaya, V; Battista, V; Bay, A; Beaucourt, L; Beddow, J; Bedeschi, F; Bediaga, I; Bel, L J; Bellee, V; Belloli, N; Belyaev, I; Ben-Haim, E; Bencivenni, G; Benson, S; Benton, J; Berezhnoy, A; Bernet, R; Bertolin, A; Betti, F; Bettler, M-O; van Beuzekom, M; Bifani, S; Billoir, P; Bird, T; Birnkraut, A; Bizzeti, A; Blake, T; Blanc, F; Blouw, J; Blusk, S; Bocci, V; Bondar, A; Bondar, N; Bonivento, W; Borgheresi, A; Borghi, S; Borisyak, M; Borsato, M; Boubdir, M; Bowcock, T J V; Bowen, E; Bozzi, C; Braun, S; Britsch, M; Britton, T; Brodzicka, J; Buchanan, E; Burr, C; Bursche, A; Buytaert, J; Cadeddu, S; Calabrese, R; Calvi, M; Calvo Gomez, M; Campana, P; Campora Perez, D; Capriotti, L; Carbone, A; Carboni, G; Cardinale, R; Cardini, A; Carniti, P; Carson, L; Carvalho Akiba, K; Casse, G; Cassina, L; Castillo Garcia, L; Cattaneo, M; Cauet, Ch; Cavallero, G; Cenci, R; Charles, M; Charpentier, Ph; Chatzikonstantinidis, G; Chefdeville, M; Chen, S; Cheung, S-F; Chobanova, V; Chrzaszcz, M; Cid Vidal, X; Ciezarek, G; Clarke, P E L; Clemencic, M; Cliff, H V; Closier, J; Coco, V; Cogan, J; Cogneras, E; Cogoni, V; Cojocariu, L; Collazuol, G; Collins, P; Comerma-Montells, A; Contu, A; Cook, A; Coquereau, S; Corti, G; Corvo, M; Couturier, B; Cowan, G A; Craik, D C; Crocombe, A; Cruz Torres, M; Cunliffe, S; Currie, R; D'Ambrosio, C; Dall'Occo, E; Dalseno, J; David, P N Y; Davis, A; De Aguiar Francisco, O; De Bruyn, K; De Capua, S; De Cian, M; De Miranda, J M; De Paula, L; De Simone, P; Dean, C-T; Decamp, D; Deckenhoff, M; Del Buono, L; Déléage, N; Demmer, M; Dendek, A; Derkach, D; Deschamps, O; Dettori, F; Dey, B; Di Canto, A; Dijkstra, H; Dordei, F; Dorigo, M; Dosil Suárez, A; Dovbnya, A; Dreimanis, K; Dufour, L; Dujany, G; Dungs, K; Durante, P; Dzhelyadin, R; Dziurda, A; Dzyuba, A; Easo, S; Egede, U; Egorychev, V; Eidelman, S; Eisenhardt, S; Eitschberger, U; Ekelhof, R; Eklund, L; El Rifai, I; Elsasser, Ch; Ely, S; Esen, S; Evans, H M; Evans, T; Falabella, A; Färber, C; Farley, N; Farry, S; Fay, R; Fazzini, D; Ferguson, D; Fernandez Albor, V; Ferrari, F; Ferreira Rodrigues, F; Ferro-Luzzi, M; Filippov, S; Fiore, M; Fiorini, M; Firlej, M; Fitzpatrick, C; Fiutowski, T; Fleuret, F; Fohl, K; Fontana, M; Fontanelli, F; Forshaw, D C; Forty, R; Frank, M; Frei, C; Frosini, M; Fu, J; Furfaro, E; Gallas Torreira, A; Galli, D; Gallorini, S; Gambetta, S; Gandelman, M; Gandini, P; Gao, Y; García Pardiñas, J; Garra Tico, J; Garrido, L; Garsed, P J; Gascon, D; Gaspar, C; Gavardi, L; Gazzoni, G; Gerick, D; Gersabeck, E; Gersabeck, M; Gershon, T; Ghez, Ph; Gianì, S; Gibson, V; Girard, O G; Giubega, L; Gligorov, V V; Göbel, C; Golubkov, D; Golutvin, A; Gomes, A; Gotti, C; Grabalosa Gándara, M; Graciani Diaz, R; Granado Cardoso, L A; Graugés, E; Graverini, E; Graziani, G; Grecu, A; Griffith, P; Grillo, L; Grünberg, O; Gushchin, E; Guz, Yu; Gys, T; Hadavizadeh, T; Hadjivasiliou, C; Haefeli, G; Haen, C; Haines, S C; Hall, S; Hamilton, B; Han, X; Hansmann-Menzemer, S; Harnew, N; Harnew, S T; Harrison, J; He, J; Head, T; Heister, A; Hennessy, K; Henrard, P; Henry, L; Hernando Morata, J A; van Herwijnen, E; Heß, M; Hicheur, A; Hill, D; Hoballah, M; Hombach, C; Hongming, L; Hulsbergen, W; Humair, T; Hushchyn, M; Hussain, N; Hutchcroft, D; Idzik, M; Ilten, P; Jacobsson, R; Jaeger, A; Jalocha, J; Jans, E; Jawahery, A; John, M; Johnson, D; Jones, C R; Joram, C; Jost, B; Jurik, N; Kandybei, S; Kanso, W; Karacson, M; Karbach, T M; Karodia, S; Kecke, M; Kelsey, M; Kenyon, I R; Kenzie, M; Ketel, T; Khairullin, E; Khanji, B; Khurewathanakul, C; Kirn, T; Klaver, S; Klimaszewski, K; Kolpin, M; Komarov, I; Koopman, R F; Koppenburg, P; Kozeiha, M; Kravchuk, L; Kreplin, K; Kreps, M; Krokovny, P; Kruse, F; Krzemien, W; Kucewicz, W; Kucharczyk, M; Kudryavtsev, V; Kuonen, A K; Kurek, K; Kvaratskheliya, T; Lacarrere, D; Lafferty, G; Lai, A; Lambert, D; Lanfranchi, G; Langenbruch, C; Langhans, B; Latham, T; Lazzeroni, C; Le Gac, R; van Leerdam, J; Lees, J-P; Lefèvre, R; Leflat, A; Lefrançois, J; Lemaitre, F; Lemos Cid, E; Leroy, O; Lesiak, T; Leverington, B; Li, Y; Likhomanenko, T; Lindner, R; Linn, C; Lionetto, F; Liu, B; Liu, X; Loh, D; Longstaff, I; Lopes, J H; Lucchesi, D; Lucio Martinez, M; Luo, H; Lupato, A; Luppi, E; Lupton, O; Lusardi, N; Lusiani, A; Lyu, X; Machefert, F; Maciuc, F; Maev, O; Maguire, K; Malde, S; Malinin, A; Manca, G; Mancinelli, G; Manning, P; Mapelli, A; Maratas, J; Marchand, J F; Marconi, U; Marin Benito, C; Marino, P; Marks, J; Martellotti, G; Martin, M; Martinelli, M; Martinez Santos, D; Martinez Vidal, F; Martins Tostes, D; Massacrier, L M; Massafferri, A; Matev, R; Mathad, A; Mathe, Z; Matteuzzi, C; Mauri, A; Maurin, B; Mazurov, A; McCann, M; McCarthy, J; McNab, A; McNulty, R; Meadows, B; Meier, F; Meissner, M; Melnychuk, D; Merk, M; Merli, A; Michielin, E; Milanes, D A; Minard, M-N; Mitzel, D S; Molina Rodriguez, J; Monroy, I A; Monteil, S; Morandin, M; Morawski, P; Mordà, A; Morello, M J; Moron, J; Morris, A B; Mountain, R; Muheim, F; Mulder, M M; Müller, D; Müller, J; Müller, K; Müller, V; Mussini, M; Muster, B; Naik, P; Nakada, T; Nandakumar, R; Nandi, A; Nasteva, I; Needham, M; Neri, N; Neubert, S; Neufeld, N; Neuner, M; Nguyen, A D; Nguyen-Mau, C; Niess, V; Nieswand, S; Niet, R; Nikitin, N; Nikodem, T; Novoselov, A; O'Hanlon, D P; Oblakowska-Mucha, A; Obraztsov, V; Ogilvy, S; Okhrimenko, O; Oldeman, R; Onderwater, C J G; Osorio Rodrigues, B; Otalora Goicochea, J M; Otto, A; Owen, P; Oyanguren, A; Palano, A; Palombo, F; Palutan, M; Panman, J; Papanestis, A; Pappagallo, M; Pappalardo, L L; Pappenheimer, C; Parker, W; Parkes, C; Passaleva, G; Patel, G D; Patel, M; Patrignani, C; Pearce, A; Pellegrino, A; Penso, G; Pepe Altarelli, M; Perazzini, S; Perret, P; Pescatore, L; Petridis, K; Petrolini, A; Petruzzo, M; Picatoste Olloqui, E; Pietrzyk, B; Pikies, M; Pinci, D; Pistone, A; Piucci, A; Playfer, S; Plo Casasus, M; Poikela, T; Polci, F; Poluektov, A; Polyakov, I; Polycarpo, E; Popov, A; Popov, D; Popovici, B; Potterat, C; Price, E; Price, J D; Prisciandaro, J; Pritchard, A; Prouve, C; Pugatch, V; Puig Navarro, A; Punzi, G; Qian, W; Quagliani, R; Rachwal, B; Rademacker, J H; Rama, M; Ramos Pernas, M; Rangel, M S; Raniuk, I; Raven, G; Redi, F; Reichert, S; Dos Reis, A C; Renaudin, V; Ricciardi, S; Richards, S; Rihl, M; Rinnert, K; Rives Molina, V; Robbe, P; Rodrigues, A B; Rodrigues, E; Rodriguez Lopez, J A; Rodriguez Perez, P; Rogozhnikov, A; Roiser, S; Romanovsky, V; Romero Vidal, A; Ronayne, J W; Rotondo, M; Ruf, T; Ruiz Valls, P; Saborido Silva, J J; Sagidova, N; Saitta, B; Salustino Guimaraes, V; Sanchez Mayordomo, C; Sanmartin Sedes, B; Santacesaria, R; Santamarina Rios, C; Santimaria, M; Santovetti, E; Sarti, A; Satriano, C; Satta, A; Saunders, D M; Savrina, D; Schael, S; Schiller, M; Schindler, H; Schlupp, M; Schmelling, M; Schmelzer, T; Schmidt, B; Schneider, O; Schopper, A; Schubiger, M; Schune, M-H; Schwemmer, R; Sciascia, B; Sciubba, A; Semennikov, A; Sergi, A; Serra, N; Serrano, J; Sestini, L; Seyfert, P; Shapkin, M; Shapoval, I; Shcheglov, Y; Shears, T; Shekhtman, L; Shevchenko, V; Shires, A; Siddi, B G; Silva Coutinho, R; Silva de Oliveira, L; Simi, G; Sirendi, M; Skidmore, N; Skwarnicki, T; Smith, E; Smith, I T; Smith, J; Smith, M; Snoek, H; Sokoloff, M D; Soler, F J P; Soomro, F; Souza, D; Souza De Paula, B; Spaan, B; Spradlin, P; Sridharan, S; Stagni, F; Stahl, M; Stahl, S; Stefkova, S; Steinkamp, O; Stenyakin, O; Stevenson, S; Stoica, S; Stone, S; Storaci, B; Stracka, S; Straticiuc, M; Straumann, U; Sun, L; Sutcliffe, W; Swientek, K; Swientek, S; Syropoulos, V; Szczekowski, M; Szumlak, T; T'Jampens, S; Tayduganov, A; Tekampe, T; Tellarini, G; Teubert, F; Thomas, C; Thomas, E; van Tilburg, J; Tisserand, V; Tobin, M; Tolk, S; Tomassetti, L; Tonelli, D; Topp-Joergensen, S; Tournefier, E; Tourneur, S; Trabelsi, K; Traill, M; Tran, M T; Tresch, M; Trisovic, A; Tsaregorodtsev, A; Tsopelas, P; Tuning, N; Ukleja, A; Ustyuzhanin, A; Uwer, U; Vacca, C; Vagnoni, V; Valat, S; Valenti, G; Vallier, A; Vazquez Gomez, R; Vazquez Regueiro, P; Vázquez Sierra, C; Vecchi, S; van Veghel, M; Velthuis, J J; Veltri, M; Veneziano, G; Vesterinen, M; Viaud, B; Vieira, D; Vieites Diaz, M; Vilasis-Cardona, X; Volkov, V; Vollhardt, A; Voong, D; Vorobyev, A; Vorobyev, V; Voß, C; de Vries, J A; Waldi, R; Wallace, C; Wallace, R; Walsh, J; Wang, J; Ward, D R; Watson, N K; Websdale, D; Weiden, A; Whitehead, M; Wicht, J; Wilkinson, G; Wilkinson, M; Williams, M; Williams, M P; Williams, M; Williams, T; Wilson, F F; Wimberley, J; Wishahi, J; Wislicki, W; Witek, M; Wormser, G; Wotton, S A; Wraight, K; Wright, S; Wyllie, K; Xie, Y; Xu, Z; Yang, Z; Yin, H; Yu, J; Yuan, X; Yushchenko, O; Zangoli, M; Zavertyaev, M; Zhang, L; Zhang, Y; Zhelezov, A; Zheng, Y; Zhokhov, A; Zhong, L; Zhukov, V; Zucchelli, S

    2016-08-19

    The data sample of Λ_{b}^{0}→J/ψpK^{-} decays acquired with the LHCb detector from 7 and 8 TeV pp collisions, corresponding to an integrated luminosity of 3  fb^{-1}, is inspected for the presence of J/ψp or J/ψK^{-} contributions with minimal assumptions about K^{-}p contributions. It is demonstrated at more than nine standard deviations that Λ_{b}^{0}→J/ψpK^{-} decays cannot be described with K^{-}p contributions alone, and that J/ψp contributions play a dominant role in this incompatibility. These model-independent results support the previously obtained model-dependent evidence for P_{c}^{+}→J/ψp charmonium-pentaquark states in the same data sample.

  6. Numerical study of the Kitaev-Heisenberg chain

    NASA Astrophysics Data System (ADS)

    Agrapidis, Cliò Efthimia; van den Brink, Jeroen; Nishimoto, Satoshi

    2018-05-01

    We study the one-dimensional Kitaev-Heisenberg model as a possible realization of magnetic degrees of freedom of the K-intercalated honeycomb-lattice ruthenium trichloride α-RuCl3, denoted as K0.5RuClm. First, we discuss the possible charge ordering pattern in K0.5RuClm, where half of the j =1/2 spins are replaced by nonmagnetic ions in the honeycomb layer. Next, we investigate the low-energy excitations of the 1D Kitaev-Heisenberg model by calculating the dynamical spin structure factor using the Lanczos exact-diagonalization method. In the vicinity of Kitaev limit, there exist two well-separated dispersions. The bandwidth of each dispersion depends on the Heisenberg and Kitaev terms. This result may be relevant to the low-lying magnetic excitations of K0.5RuClm.

  7. Investigation of possible phase transition of the frustrated spin-1/2 J 1-J 2-J 3 model on the square lattice.

    PubMed

    Hu, Ai-Yuan; Wang, Huai-Yu

    2017-09-05

    The frustrated spin-1/2 J 1 -J 2 -J 3 antiferromagnet with exchange anisotropy on the two-dimensional square lattice is investigated. The exchange anisotropy is presented by η with 0 ≤ η < 1. The effects of the J 1 , J 2 , J 3 and anisotropy on the possible phase transition of the Néel state and collinear state are studied comprehensively. Our results indicate that for J 3  > 0 there are upper limits [Formula: see text] and η c values. When 0 < J 3  ≤ [Formula: see text] and 0 ≤ η ≤ η c , the Néel and collinear states have the same order-disorder transition point at J 2  = J 1 /2. Nevertheless, when the J 3 and η values beyond the upper limits, it is a paramagnetic phase at J 2  = J 1 /2. For J 3  < 0, in the case of 0 ≤ η < 1, the two states always have the same critical temperature as long as J 2  = J 1 /2. Therefore, for J 2  = J 1 /2, under such parameters, a first-order phase transition between the two states for these two cases below the critical temperatures may occur. When J 2  ≠ J 1 /2, the Néel and collinear states may also exist, while they have different critical temperatures. When J 2  > J 1 /2, a first-order phase transition between the two states may also occur. However, for J 2  < J 1 /2, the Néel state is always more stable than the collinear state.

  8. J domain independent functions of J proteins.

    PubMed

    Ajit Tamadaddi, Chetana; Sahi, Chandan

    2016-07-01

    Heat shock proteins of 40 kDa (Hsp40s), also called J proteins, are obligate partners of Hsp70s. Via their highly conserved and functionally critical J domain, J proteins interact and modulate the activity of their Hsp70 partners. Mutations in the critical residues in the J domain often result in the null phenotype for the J protein in question. However, as more J proteins have been characterized, it is becoming increasingly clear that a significant number of J proteins do not "completely" rely on their J domains to carry out their cellular functions, as previously thought. In some cases, regions outside the highly conserved J domain have become more important making the J domain dispensable for some, if not for all functions of a J protein. This has profound effects on the evolution of such J proteins. Here we present selected examples of J proteins that perform J domain independent functions and discuss this in the context of evolution of J proteins with dispensable J domains and J-like proteins in eukaryotes.

  9. TSCA Section 5(a)(3)(C) Determination for Microbial Commercial Activity Notice (MCAN) J-16-0011, J-16-0012, J-16-0013, J-16-0014, J-16-0015, and J-16-0016

    EPA Pesticide Factsheets

    This document describes EPA's Microbial Commercial Activity Notice (MCAN) review determination under amended TSCA for J-16-0011, J-16-0012, J-16-0013, J-16-0014, J-16-0015, and J-16-0016, a biofuel producing organism.

  10. Nearly Deconfined Spinon Excitations in the Square-Lattice Spin-1 /2 Heisenberg Antiferromagnet

    NASA Astrophysics Data System (ADS)

    Shao, Hui; Qin, Yan Qi; Capponi, Sylvain; Chesi, Stefano; Meng, Zi Yang; Sandvik, Anders W.

    2017-10-01

    We study the spin-excitation spectrum (dynamic structure factor) of the spin-1 /2 square-lattice Heisenberg antiferromagnet and an extended model (the J -Q model) including four-spin interactions Q in addition to the Heisenberg exchange J . Using an improved method for stochastic analytic continuation of imaginary-time correlation functions computed with quantum Monte Carlo simulations, we can treat the sharp (δ -function) contribution to the structure factor expected from spin-wave (magnon) excitations, in addition to resolving a continuum above the magnon energy. Spectra for the Heisenberg model are in excellent agreement with recent neutron-scattering experiments on Cu (DCOO )2.4 D2O , where a broad spectral-weight continuum at wave vector q =(π ,0 ) was interpreted as deconfined spinons, i.e., fractional excitations carrying half of the spin of a magnon. Our results at (π ,0 ) show a similar reduction of the magnon weight and a large continuum, while the continuum is much smaller at q =(π /2 ,π /2 ) (as also seen experimentally). We further investigate the reasons for the small magnon weight at (π ,0 ) and the nature of the corresponding excitation by studying the evolution of the spectral functions in the J -Q model. Upon turning on the Q interaction, we observe a rapid reduction of the magnon weight to zero, well before the system undergoes a deconfined quantum phase transition into a nonmagnetic spontaneously dimerized state. Based on these results, we reinterpret the picture of deconfined spinons at (π ,0 ) in the experiments as nearly deconfined spinons—a precursor to deconfined quantum criticality. To further elucidate the picture of a fragile (π ,0 )-magnon pole in the Heisenberg model and its depletion in the J -Q model, we introduce an effective model of the excitations in which a magnon can split into two spinons that do not separate but fluctuate in and out of the magnon space (in analogy to the resonance between a photon and a particle

  11. Early phenotypical diagnoses in Trembler-J mice model.

    PubMed

    Rosso, Gonzalo; Cal, Karina; Canclini, Lucía; Damián, Juan Pablo; Ruiz, Paul; Rodríguez, Héctor; Sotelo, José Roberto; Vazquez, Cristina; Kun, Alejandra

    2010-06-30

    Pmp-22 mutant mice (Trembler-J: B6.D2-Pmp22J>/J), are used as a model to study Charcot-Marie-Tooth type 1A (CMT1A). The identification of individual genotypes is a routine in the management of the Tr(J) colony. The earliest phenotypic manifestation of the pmp-22 mutation is just about 20th postnatal days, when pups begin to tremble. In this study, a rapid and simple diagnostic method was developed by modifying the Tail Suspension Test (MTST) to determine the difference between the Tr(J) and the wild-type mice phenotype. The animal behavioral phenotypes generated during the test were consistent with the specific genotype of each animal. The MTST allowed us to infer the heterozygous genotype in early postnatal stages, at 11 days after birth. The motor impairment of Tr(J) mice was also analyzed by a Fixed Bar Test (FBT), which revealed the disease evolution according to age. The main advantages of MTST are its objectivity, simplicity, and from the viewpoint of animal welfare, it is a non-invasive technique that combined with his rapidity show its very well applicability for use from an early age in these mice. Copyright 2010 Elsevier B.V. All rights reserved.

  12. Investigations of the Quantum Correlation in Two-Qubit Heisenberg XYZ Model with Decoherence

    NASA Astrophysics Data System (ADS)

    Guo-Hui, Yang

    2017-03-01

    Quantum correlation dynamics in an anisotropic Heisenberg XYZ model under decoherence is investigated with the use of concurrence C and quantum discord (QD). With the Werner state as the initial state, we discuss the influence of mixture degree r on the dynamics. There are some difference between the time evolution behaviors of these two correlation measures with different value of r. For 0 ≤ r ≤ 1/3, there exists quantum discord but no entanglement; For 1/3< r<1, there is a "entanglement sudden death and birth" phenomenon in the concurrence but not in the QD; For r=1, there is one interesting thing that the concurrence decays from 1 to a minimum value close to 0 but the QD vanish. In addition, we have investigated the influence of different parameters on the two correlation measures. It has been found that, the concurrence and QD both exhibit osillatory behaviors with the time evolution, which is independent on the magnetic field B and the coupling coefficient J z . However, the Dzyaloshinskii-Moriya interaction (D) and coupling coefficient J have strong influence on concurrence and QD. With the increasing of the D or J, the frequency of the oscillation getting larger. When time is fixed, with the increasing of D or J, the concurrence and QD change periodically.

  13. cyNeo4j: connecting Neo4j and Cytoscape

    PubMed Central

    Summer, Georg; Kelder, Thomas; Ono, Keiichiro; Radonjic, Marijana; Heymans, Stephane; Demchak, Barry

    2015-01-01

    Summary: We developed cyNeo4j, a Cytoscape App to link Cytoscape and Neo4j databases to utilize the performance and storage capacities Neo4j offers. We implemented a Neo4j NetworkAnalyzer, ForceAtlas2 layout and Cypher component to demonstrate the possibilities a distributed setup of Cytoscape and Neo4j have. Availability and implementation: The app is available from the Cytoscape App Store at http://apps.cytoscape.org/apps/cyneo4j, the Neo4j plugins at www.github.com/gsummer/cyneo4j-parent and the community and commercial editions of Neo4j can be found at http://www.neo4j.com. Contact: georg.summer@gmail.com PMID:26272981

  14. Rotational symmetry breaking toward a string-valence bond solid phase in frustrated J1 -J2 transverse field Ising model

    NASA Astrophysics Data System (ADS)

    Sadrzadeh, M.; Langari, A.

    2018-06-01

    We study the effect of quantum fluctuations by means of a transverse magnetic field (Γ) on the highly degenerate ground state of antiferromagnetic J1 -J2 Ising model on the square lattice, at the limit J2 /J1 = 0.5 . We show that harmonic quantum fluctuations based on single spin flips can not lift such degeneracy, however an-harmonic quantum fluctuations based on multi spin cluster flip excitations lift the degeneracy toward a unique ground state with string-valence bond solid (VBS) nature. A cluster operator formalism has been implemented to incorporate an-harmonic quantum fluctuations. We show that cluster-type excitations of the model lead not only to lower the excitation energy compared with a single-spin flip but also to lift the extensive degeneracy in favor of a string-VBS state, which breaks lattice rotational symmetry with only two fold degeneracy. The tendency toward the broken symmetry state is justified by numerical exact diagonalization. Moreover, we introduce a map to find the relation between the present model on the checkerboard and square lattices.

  15. The solar gravitational figure: J2 and J4

    NASA Technical Reports Server (NTRS)

    Ulrich, R. K.; Hawkins, G. W.

    1980-01-01

    The theory of the solar gravitational figure is derived including the effects of differential rotation. It is shown that J sub 4 is smaller than J sub 2 by a factor of about 10 rather than being of order J sub 2 squared as would be expected for rigid rotation. The dependence of both J sub 2 and J sub 4 on envelope mass is given. High order p-mode oscillation frequencies provide a constraint on solar structure which limits the range in envelope mass to the range 0.01 M sub E/solar mass 0.04. For an assumed rotation law in which the surface pattern of differential rotation extends uniformly throughout the convective envelope, this structural constraint limits the ranges of J sub 2 and J sub 4 in units of 10 to the -8th power to 10 J sub 2 15 and 0.6 -J sub 4 1.5. Deviations from these ranges would imply that the rotation law is not constant with depth and would provide a measure of this rotation law.

  16. An energy-dependent numerical model for the condensation probability, γ j

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kerby, Leslie Marie

    The “condensation” probability, γ j, is an important variable in the preequilibrium stage of nuclear spallation reactions. It represents the probability that p j excited nucleons (excitons) will “condense” to form complex particle type j in the excited residual nucleus. In addition, it has a significant impact on the emission width, or probability of emitting fragment type j from the residual nucleus. Previous formulations for γ j were energy-independent and valid for fragments up to 4He only. This paper explores the formulation of a new model for γ j, one which is energy-dependent and valid for up to 28Mg, andmore » which provides improved fits compared to experimental fragment spectra.« less

  17. An energy-dependent numerical model for the condensation probability, γ j

    DOE PAGES

    Kerby, Leslie Marie

    2016-12-09

    The “condensation” probability, γ j, is an important variable in the preequilibrium stage of nuclear spallation reactions. It represents the probability that p j excited nucleons (excitons) will “condense” to form complex particle type j in the excited residual nucleus. In addition, it has a significant impact on the emission width, or probability of emitting fragment type j from the residual nucleus. Previous formulations for γ j were energy-independent and valid for fragments up to 4He only. This paper explores the formulation of a new model for γ j, one which is energy-dependent and valid for up to 28Mg, andmore » which provides improved fits compared to experimental fragment spectra.« less

  18. Spin-1/2 Heisenberg antiferromagnet on an anisotropic triangular lattice

    NASA Astrophysics Data System (ADS)

    Starykh, Oleg

    2007-03-01

    The Triangular lattice spin-1/2 Heisenberg AntiFerromagnet (TAF) is a prototypical model of frustrated quantum magnetism. While it is believed to exhibit long-range order in the isotropic limit, changes such as spatial anisotropy can alter the delicate balance amongst competing ground states. I will describe the static and dynamic properties of the spatially anisotropic TAF, with inter-chain diagonal exchange J' much weaker than the intrachain exchange J. Treating J' as a perturbation of decoupled Heisenberg spin-1/2 chains, I find that the ground state is spontaneously dimerized in a four-fold degenerate zig-zag pattern. This dimerization instability is driven by quantum fluctuations, which are dramatically enhanced here by the frustrated nature of inter-chain exchange. A magnetic field partially relieves frustration, by canting the spins along the field direction, and causes a quantum phase transition into a magnetically-ordered spin-density-wave phase. This is followed by cone and, finally, fully polarized (saturated) phases, as a function of increasing magnetic field. I show that many of these features are in fact observed in experiments on the celebrated material Cs2CuCl4 (J'/J =1/3). I will also discuss the significant modification of the phase diagram by symmetry-breaking anisotropic Dzyaloshinskii-Moriya (DM) interactions, present in this interesting magnet. In addition to static and thermodynamic properties, the proposed ``one-dimensional'' approach offers a compelling explanation of the unusual experimentally measured dynamical structure factor of Cs2CuCl4 in terms of descendants of one-dimensional spinons. Quite generally, I find characteristic features of a momentum-dependent spinon bound state and a dispersing incoherent excitation in the structure factor, in agreement with experiments.

  19. KC-130J Transport Aircraft (KC-130J)

    DTIC Science & Technology

    2015-12-01

    Selected Acquisition Report ( SAR ) RCS: DD-A&T(Q&A)823-433 KC-130J Transport Aircraft (KC-130J) As of FY 2017 President’s Budget Defense Acquisition...Management Information Retrieval (DAMIR) March 23, 2016 15:23:28 UNCLASSIFIED KC-130J December 2015 SAR March 23, 2016 15:23:28 UNCLASSIFIED 2...Document OSD - Office of the Secretary of Defense O&S - Operating and Support PAUC - Program Acquisition Unit Cost KC-130J December 2015 SAR March 23

  20. Observation of ψ(3686)→e^{+}e^{-}χ_{cJ} and χ_{cJ}→e^{+}e^{-}J/ψ.

    PubMed

    Ablikim, M; Achasov, M N; Ai, X C; Albayrak, O; Albrecht, M; Ambrose, D J; Amoroso, A; An, F F; An, Q; Bai, J Z; Baldini Ferroli, R; Ban, Y; Bennett, D W; Bennett, J V; Bertani, M; Bettoni, D; Bian, J M; Bianchi, F; Boger, E; Boyko, I; Briere, R A; Cai, H; Cai, X; Cakir, O; Calcaterra, A; Cao, G F; Cetin, S A; Chang, J F; Chelkov, G; Chen, G; Chen, H S; Chen, H Y; Chen, J C; Chen, M L; Chen, S; Chen, S J; Chen, X; Chen, X R; Chen, Y B; Cheng, H P; Chu, X K; Cibinetto, G; Dai, H L; Dai, J P; Dbeyssi, A; Dedovich, D; Deng, Z Y; Denig, A; Denysenko, I; Destefanis, M; De Mori, F; Ding, Y; Dong, C; Dong, J; Dong, L Y; Dong, M Y; Dou, Z L; Du, S X; Duan, P F; Fan, J Z; Fang, J; Fang, S S; Fang, X; Fang, Y; Farinelli, R; Fava, L; Fedorov, O; Feldbauer, F; Felici, G; Feng, C Q; Fioravanti, E; Fritsch, M; Fu, C D; Gao, Q; Gao, X L; Gao, X Y; Gao, Y; Gao, Z; Garzia, I; Goetzen, K; Gong, L; Gong, W X; Gradl, W; Greco, M; Gu, M H; Gu, Y T; Guan, Y H; Guo, A Q; Guo, L B; Guo, R P; Guo, Y; Guo, Y P; Haddadi, Z; Hafner, A; Han, S; Hao, X Q; Harris, F A; He, K L; Held, T; Heng, Y K; Hou, Z L; Hu, C; Hu, H M; Hu, J F; Hu, T; Hu, Y; Huang, G S; Huang, J S; Huang, X T; Huang, X Z; Huang, Y; Huang, Z L; Hussain, T; Ji, Q; Ji, Q P; Ji, X B; Ji, X L; Jiang, L W; Jiang, X S; Jiang, X Y; Jiao, J B; Jiao, Z; Jin, D P; Jin, S; Johansson, T; Julin, A; Kalantar-Nayestanaki, N; Kang, X L; Kang, X S; Kavatsyuk, M; Ke, B C; Kiese, P; Kliemt, R; Kloss, B; Kolcu, O B; Kopf, B; Kornicer, M; Kupsc, A; Kühn, W; Lange, J S; Lara, M; Larin, P; Leng, C; Li, C; Li, Cheng; Li, D M; Li, F; Li, F Y; Li, G; Li, H B; Li, H J; Li, J C; Li, Jin; Li, K; Li, K; Li, Lei; Li, P R; Li, Q Y; Li, T; Li, W D; Li, W G; Li, X L; Li, X N; Li, X Q; Li, Y B; Li, Z B; Liang, H; Liang, Y F; Liang, Y T; Liao, G R; Lin, D X; Liu, B; Liu, B J; Liu, C X; Liu, D; Liu, F H; Liu, Fang; Liu, Feng; Liu, H B; Liu, H H; Liu, H H; Liu, H M; Liu, J; Liu, J B; Liu, J P; Liu, J Y; Liu, K; Liu, K Y; Liu, L D; Liu, P L; Liu, Q; Liu, S B; Liu, X; Liu, Y B; Liu, Z A; Liu, Zhiqing; Loehner, H; Lou, X C; Lu, H J; Lu, J G; Lu, Y; Lu, Y P; Luo, C L; Luo, M X; Luo, T; Luo, X L; Lyu, X R; Ma, F C; Ma, H L; Ma, L L; Ma, M M; Ma, Q M; Ma, T; Ma, X N; Ma, X Y; Ma, Y M; Maas, F E; Maggiora, M; Mao, Y J; Mao, Z P; Marcello, S; Messchendorp, J G; Min, J; Mitchell, R E; Mo, X H; Mo, Y J; Morales Morales, C; Muchnoi, N Yu; Muramatsu, H; Nefedov, Y; Nerling, F; Nikolaev, I B; Ning, Z; Nisar, S; Niu, S L; Niu, X Y; Olsen, S L; Ouyang, Q; Pacetti, S; Pan, Y; Patteri, P; Pelizaeus, M; Peng, H P; Peters, K; Pettersson, J; Ping, J L; Ping, R G; Poling, R; Prasad, V; Qi, H R; Qi, M; Qian, S; Qiao, C F; Qin, L Q; Qin, N; Qin, X S; Qin, Z H; Qiu, J F; Rashid, K H; Redmer, C F; Ripka, M; Rong, G; Rosner, Ch; Ruan, X D; Sarantsev, A; Savrié, M; Schoenning, K; Schumann, S; Shan, W; Shao, M; Shen, C P; Shen, P X; Shen, X Y; Sheng, H Y; Shi, M; Song, W M; Song, X Y; Sosio, S; Spataro, S; Sun, G X; Sun, J F; Sun, S S; Sun, X H; Sun, Y J; Sun, Y Z; Sun, Z J; Sun, Z T; Tang, C J; Tang, X; Tapan, I; Thorndike, E H; Tiemens, M; Ullrich, M; Uman, I; Varner, G S; Wang, B; Wang, B L; Wang, D; Wang, D Y; Wang, K; Wang, L L; Wang, L S; Wang, M; Wang, P; Wang, P L; Wang, S G; Wang, W; Wang, W P; Wang, X F; Wang, Y; Wang, Y D; Wang, Y F; Wang, Y Q; Wang, Z; Wang, Z G; Wang, Z H; Wang, Z Y; Wang, Z Y; Weber, T; Wei, D H; Wei, J B; Weidenkaff, P; Wen, S P; Wiedner, U; Wolke, M; Wu, L H; Wu, L J; Wu, Z; Xia, L; Xia, L G; Xia, Y; Xiao, D; Xiao, H; Xiao, Z J; Xie, Y G; Xiu, Q L; Xu, G F; Xu, J J; Xu, L; Xu, Q J; Xu, Q N; Xu, X P; Yan, L; Yan, W B; Yan, W C; Yan, Y H; Yang, H J; Yang, H X; Yang, L; Yang, Y X; Ye, M; Ye, M H; Yin, J H; Yu, B X; Yu, C X; Yu, J S; Yuan, C Z; Yuan, W L; Yuan, Y; Yuncu, A; Zafar, A A; Zallo, A; Zeng, Y; Zeng, Z; Zhang, B X; Zhang, B Y; Zhang, C; Zhang, C C; Zhang, D H; Zhang, H H; Zhang, H Y; Zhang, J; Zhang, J J; Zhang, J L; Zhang, J Q; Zhang, J W; Zhang, J Y; Zhang, J Z; Zhang, K; Zhang, L; Zhang, S Q; Zhang, X Y; Zhang, Y; Zhang, Y H; Zhang, Y N; Zhang, Y T; Zhang, Yu; Zhang, Z H; Zhang, Z P; Zhang, Z Y; Zhao, G; Zhao, J W; Zhao, J Y; Zhao, J Z; Zhao, Lei; Zhao, Ling; Zhao, M G; Zhao, Q; Zhao, Q W; Zhao, S J; Zhao, T C; Zhao, Y B; Zhao, Z G; Zhemchugov, A; Zheng, B; Zheng, J P; Zheng, W J; Zheng, Y H; Zhong, B; Zhou, L; Zhou, X; Zhou, X K; Zhou, X R; Zhou, X Y; Zhu, K; Zhu, K J; Zhu, S; Zhu, S H; Zhu, X L; Zhu, Y C; Zhu, Y S; Zhu, Z A; Zhuang, J; Zotti, L; Zou, B S; Zou, J H

    2017-06-02

    Using 4.479×10^{8}  ψ(3686) events collected with the BESIII detector, we search for the decays ψ(3686)→e^{+}e^{-}χ_{cJ} and χ_{cJ}→e^{+}e^{-}J/ψ, where J=0, 1, 2. The decays ψ(3686)→e^{+}e^{-}χ_{cJ} and χ_{cJ}→e^{+}e^{-}J/ψ are observed for the first time. The measured branching fractions are B(ψ(3686)→e^{+}e^{-}χ_{cJ})=(11.7±2.5±1.0)×10^{-4}, (8.6±0.3±0.6)×10^{-4}, (6.9±0.5±0.6)×10^{-4} for J=0, 1, 2, and B(χ_{cJ}→e^{+}e^{-}J/ψ)=(1.51±0.30±0.13)×10^{-4}, (3.73±0.09±0.25)×10^{-3}, (2.48±0.08±0.16)×10^{-3} for J=0, 1, 2, respectively. The ratios of the branching fractions B(ψ(3686)→e^{+}e^{-}χ_{cJ})/B(ψ(3686)→γχ_{cJ}) and B(χ_{cJ}→e^{+}e^{-}J/ψ)/B(χ_{cJ}→γJ/ψ) are also reported. Also, the α values of helicity angular distributions of the e^{+}e^{-} pair are determined for ψ(3686)→e^{+}e^{-}χ_{c1,2} and χ_{c1,2}→e^{+}e^{-}J/ψ.

  1. Comparison of Two New Mouse Models of Polygenic Type 2 Diabetes at the Jackson Laboratory, NONcNZO10Lt/J and TALLYHO/JngJ

    PubMed Central

    Leiter, Edward H.; Strobel, Marjorie; Schultz, David; Schile, Andrew; Reifsnyder, Peter C.

    2013-01-01

    This review compares two novel polygenic mouse models of type 2 diabetes (T2D), TALLYHO/JngJ and NONcNZO10/LtJ, and contrasts both with the well-known C57BLKS/J-Leprdb (db/db) monogenic diabesity model. We posit that the new polygenic models are more representative of the “garden variety” obesity underlying human T2D in terms of their polygenetic rather than monogenic etiology. Moreover, the clinical phenotypes in these new models are less extreme, for example, more moderated development of obesity coupled with less extreme endocrine disturbances. The more progressive development of obesity produces a maturity-onset development of hyperglycemia in contrast to the juvenile-onset diabetes observed in the morbidly obese db/db model. Unlike the leptin receptor-deficient db/db models with central leptin resistance, the new models develop a progressive peripheral leptin resistance and are able to maintain reproductive function. Although the T2D pathophysiology in both TALLYHO/JngJ and NONcNZO10/LtJ is remarkably similar, their genetic etiologies are clearly different, underscoring the genetic heterogeneity underlying T2D in humans. PMID:23671854

  2. Comparison of Two New Mouse Models of Polygenic Type 2 Diabetes at the Jackson Laboratory, NONcNZO10Lt/J and TALLYHO/JngJ.

    PubMed

    Leiter, Edward H; Strobel, Marjorie; O'Neill, Adam; Schultz, David; Schile, Andrew; Reifsnyder, Peter C

    2013-01-01

    This review compares two novel polygenic mouse models of type 2 diabetes (T2D), TALLYHO/JngJ and NONcNZO10/LtJ, and contrasts both with the well-known C57BLKS/J-Lepr(db) (db/db) monogenic diabesity model. We posit that the new polygenic models are more representative of the "garden variety" obesity underlying human T2D in terms of their polygenetic rather than monogenic etiology. Moreover, the clinical phenotypes in these new models are less extreme, for example, more moderated development of obesity coupled with less extreme endocrine disturbances. The more progressive development of obesity produces a maturity-onset development of hyperglycemia in contrast to the juvenile-onset diabetes observed in the morbidly obese db/db model. Unlike the leptin receptor-deficient db/db models with central leptin resistance, the new models develop a progressive peripheral leptin resistance and are able to maintain reproductive function. Although the T2D pathophysiology in both TALLYHO/JngJ and NONcNZO10/LtJ is remarkably similar, their genetic etiologies are clearly different, underscoring the genetic heterogeneity underlying T2D in humans.

  3. 75 FR 33164 - Modification of Jet Routes J-32, J-38, and J-538; Minnesota

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-11

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 [Docket No. FAA-2009-1080; Airspace Docket No. 09-AGL-13] RIN 2120-AA66 Modification of Jet Routes J-32, J-38, and J-538; Minnesota AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action...

  4. J. J. Thomson goes to America.

    PubMed

    Downard, Kevin M

    2009-11-01

    Joseph John (J. J.) Thomson was an accomplished scientist who helped lay the foundations of nuclear physics. A humble man of working class roots, Thomson went on to become one of the most influential physicists of the late 19th century. He is credited with the discovery of the electron, received a Nobel Prize in physics in 1906 for investigations into the conduction of electricity by gases, was knighted in 1908, and served as a Cavendish Professor and Director of the laboratory for over 35 years from 1884. His laboratory attracted some of the world's brightest minds; Francis W. Aston, Niels H. D. Bohr, Hugh L. Callendar, Charles T. R. Wilson, Ernest Rutherford, George F. C. Searle, Geoffrey I. Taylor, and John S. E. Townsend all worked under him. This article recounts J. J. Thomson's visits to North America in 1896, 1903, 1909, and finally 1923. It presents his activities and his personal impressions of the people and society of the U.S.A. and Canada, and the science of atomic physics and chemistry in the late 1800s and early 1900s.

  5. Crystal structure and magnetic properties of cyclohexylammonium trichlorocuprate(II): A quasi 1d Heisenberg S = {1}/{2} ferromagnet

    NASA Astrophysics Data System (ADS)

    Groenendijk, H. A.; Blöte, H. W. J.; van Duyneveldt, A. J.; Gaura, R. M.; Landee, C. P.; Willett, R. D.

    1981-06-01

    The crystal structure of [C 6H 11NH 3] CuCl 3, cyclohexylammonium trichlorocuprate(II) (CHAC), is orthorhombic, space group P2 12 12 1 with a = 19.441(5), b = 8.549(2) and c = 6.190(1) Å. The salt contains chains of CuCl -3 ions along the c axis. From magnetization and susceptibility measurements it is found that the compound behaves as a one-dimensional S = {1}/{2} Heisenberg ferromagnet with J1/ k = 70(2) K. Antiferromagnetic ordering with a weak ferromagnetic moment along the a axis occurs below T c = 2.18(2) K. From the metamagnetic phase diagram the interchain interactions are derived using mean field theory: z2J2/ z1J1 = 1.1 × 10 -3 and z3J3/ z1J1 = -1.0 × 10 -4. Also a small anisotropy ( J|/ J⊥ ≈ 0.01) is found in the intrachain interaction. The measurements indicate that CHAC is one of the best approximations to the 1d Heisenberg ferromagnet known to date.

  6. 75 FR 53857 - Airworthiness Directives; Eurocopter France Model SA330J Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-02

    ... Airworthiness Directives; Eurocopter France Model SA330J Helicopters AGENCY: Federal Aviation Administration... known U.S. owners and operators of Eurocopter France (Eurocopter) Model SA330J helicopters by individual...'' rather than checking for ``play.'' This helicopter model is manufactured in France and is type...

  7. C-130J Hercules Transport Aircraft (C-130J)

    DTIC Science & Technology

    2015-12-01

    Selected Acquisition Report ( SAR ) RCS: DD-A&T(Q&A)823-220 C-130J Hercules Transport Aircraft (C-130J) As of FY 2017 President’s Budget Defense...Acquisition Management Information Retrieval (DAMIR) March 21, 2016 11:33:03 UNCLASSIFIED C-130J December 2015 SAR March 21, 2016 11:33:03...Requirements Document OSD - Office of the Secretary of Defense O&S - Operating and Support PAUC - Program Acquisition Unit Cost C-130J December 2015 SAR March 21

  8. Resonant slepton production yields CMS e e j j and e p Tj j excesses

    NASA Astrophysics Data System (ADS)

    Allanach, Ben; Biswas, Sanjoy; Mondal, Subhadeep; Mitra, Manimala

    2015-01-01

    Recent CMS searches for dileptoquark production report local excesses of 2.4 σ in an e e j j channel and 2.6 σ in an e p Tj j channel. Here, we simultaneously explain both excesses with resonant slepton production in R -parity violating supersymmetry. We consider resonant slepton production, which decays to a lepton and a chargino/neutralino, followed by three-body decays of the neutralino/chargino via an R -parity violating coupling. There are regions of parameter space which are also compatible at the 95% confidence level with a 2.8 σ e e j j excess in a recent CMS WR search, while being compatible with other direct search constraints. Phase II of the GERDA neutrinoless double beta decay (0 ν β β ) experiment will probe a sizable portion of the good-fit region.

  9. Heat capacity and monogamy relations in the mixed-three-spin XXX Heisenberg model at low temperatures

    NASA Astrophysics Data System (ADS)

    Zad, Hamid Arian; Movahhedian, Hossein

    2016-08-01

    Heat capacity of a mixed-three-spin (1/2,1,1/2) antiferromagnetic XXX Heisenberg chain is precisely investigated by use of the partition function of the system for which, spins (1,1/2) have coupling constant J1 and spins (1/2,1/2) have coupling constant J2. We verify tripartite entanglement for the model by means of the convex roof extended negativity (CREN) and concurrence as functions of temperature T, homogeneous magnetic field B and the coupling constants J1 and J2. As shown in our previous work, [H. A. Zad, Chin. Phys. B 25 (2016) 030303.] the temperature, the magnetic field and the coupling constants dependences of the heat capacity for such spin system have different behaviors for the entangled and separable states, hence, we did some useful comparisons between this quantity and negativities of its organized bipartite (sub)systems at entangled and separable states. Here, we compare the heat capacity of the mixed-three-spin (1/2,1,1/2) system with the CREN and the tripartite concurrence (as measures of the tripartite entanglement) at low temperature. Ground state phase transitions, and also, transition from ground state to some excited states are explained in detail for this system at zero temperature. Finally, we investigate the heat capacity behavior around those critical points in which these quantum phase transitions occur.

  10. J SERIES MAGAZINE. J 107 NORTH END AND REAR (EAST). ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    J SERIES MAGAZINE. J 107 NORTH END AND REAR (EAST). J 106-103 IN BACKGROUND. - Naval Magazine Lualualei, Headquarters Branch, Inert Storehouse Type, Twelfth Street between Kwajulein & New Mexico Streets, Pearl City, Honolulu County, HI

  11. Magnetic properties of a quasi-two-dimensional S =1/2 Heisenberg antiferromagnet with distorted square lattice

    NASA Astrophysics Data System (ADS)

    Yamaguchi, Hironori; Tamekuni, Yusuke; Iwasaki, Yoshiki; Otsuka, Rei; Hosokoshi, Yuko; Kida, Takanori; Hagiwara, Masayuki

    2017-06-01

    We successfully synthesize single crystals of the verdazyl radical α -2 ,3 ,5 -Cl3 -V. Ab initio molecular orbital calculations indicate that the two dominant antiferromagnetic interactions, J1 and J2 (α =J2/J1≃0.56 ), form an S =1 /2 distorted square lattice. We explain the magnetic properties based on the S =1 /2 square lattice Heisenberg antiferromagnet using the quantum Monte Carlo method, and examine the effects of the lattice distortion and the interplane interaction contribution. In the low-temperature regions below 6.4 K, we observe anisotropic magnetic behavior accompanied by a phase transition to a magnetically ordered state. The electron spin resonance signals exhibit anisotropic behavior in the temperature dependence of the resonance field and the linewidth. We explain the frequency dependence of the resonance fields in the ordered phase using a mean-field approximation with out-of-plane easy-axis anisotropy, which causes a spin-flop phase transition at approximately 0.4 T for the field perpendicular to the plane. Furthermore, the anisotropic dipole field provides supporting information regarding the presence of the easy-axis anisotropy. These results demonstrate that the lattice distortion, anisotropy, and interplane interaction of this model are sufficiently small that they do not affect the intrinsic behavior of the S =1 /2 square lattice Heisenberg antiferromagnet.

  12. Numerical Modelling Of The V-J Combinations Of The T Cell Receptor TRA/TRD Locus

    PubMed Central

    Dariz, Aurélie; Baum, Thierry Pascal; Hierle, Vivien; Demongeot, Jacques; Marche, Patrice Noël; Jouvin-Marche, Evelyne

    2010-01-01

    T-Cell antigen Receptor (TR) repertoire is generated through rearrangements of V and J genes encoding α and β chains. The quantification and frequency for every V-J combination during ontogeny and development of the immune system remain to be precisely established. We have addressed this issue by building a model able to account for Vα-Jα gene rearrangements during thymus development of mice. So we developed a numerical model on the whole TRA/TRD locus, based on experimental data, to estimate how Vα and Jα genes become accessible to rearrangements. The progressive opening of the locus to V-J gene recombinations is modeled through windows of accessibility of different sizes and with different speeds of progression. Furthermore, the possibility of successive secondary V-J rearrangements was included in the modelling. The model points out some unbalanced V-J associations resulting from a preferential access to gene rearrangements and from a non-uniform partition of the accessibility of the J genes, depending on their location in the locus. The model shows that 3 to 4 successive rearrangements are sufficient to explain the use of all the V and J genes of the locus. Finally, the model provides information on both the kinetics of rearrangements and frequencies of each V-J associations. The model accounts for the essential features of the observed rearrangements on the TRA/TRD locus and may provide a reference for the repertoire of the V-J combinatorial diversity. PMID:20174554

  13. On Nulling, Drifting, and Their Interactions in PSRs J1741-0840 and J1840-0840

    NASA Astrophysics Data System (ADS)

    Gajjar, V.; Yuan, J. P.; Yuen, R.; Wen, Z. G.; Liu, Z. Y.; Wang, N.

    2017-12-01

    We report detailed investigation of nulling and drifting behavior of two pulsars PSRs J1741-0840 and J1840-0840 observed from the Giant Meterwave Radio Telescope at 625 MHz. PSR J1741-0840 was found to show a nulling fraction (NF) of around 30% ± 5% while PSR J1840-0840 was shown to have an NF of around 50% ± 6%. We measured drifting behavior from different profile components in PSR J1840-0840 for the first time with the leading component showing drifting with 13.5 ± 0.7 periods while the weak trailing component showed drifting of around 18 ± 1 periods. Large nulling hampers accuracy of these quantities derived using standard Fourier techniques. A more accurate comparison was drawn from driftband slopes, measured after sub-pulse modeling. These measurements revealed interesting sporadic and irregular drifting behavior in both pulsars. We conclude that the previously reported different drifting periodicities in the trailing component of PSR J1741-0840 is likely due to the spread in these driftband slopes. We also find that both components of PSR J1840-0840 show similar driftband slopes within the uncertainties. Unique nulling-drifting interaction is identified in PSR J1840-0840 where, on most occasions, the pulsar tends to start nulling after what appears to be the end of a driftband. Similarly, when the pulsar switches back to an emission phase, on most occasions it starts at the beginning of a new driftband in both components. Such behaviors have not been detected in any other pulsars to our knowledge. We also found that PSR J1741-0840 seems to have no memory of its previous burst phase while PSR J1840-0840 clearly exhibits memory of its previous state even after longer nulls for both components. We discuss possible explanations for these intriguing nulling-drifting interactions seen in both pulsars based on various pulsar nulling models.

  14. Sociability and brain development in BALB/cJ and C57BL/6J mice

    PubMed Central

    Fairless, Andrew H.; Dow, Holly C.; Kreibich, Arati Sadalge; Torre, Matthew; Kuruvilla, Mariyam; Gordon, Elliot; Morton, Elizabeth A.; Tan, Junhao; Berrettini, Wade H.; Li, Hongzhe; Abel, Ted; Brodkin, Edward S.

    2012-01-01

    Sociability—the tendency to seek social interaction–propels the development of social cognition and social skills, but is disrupted in autism spectrum disorders (ASD). BALB/cJ and C57BL/6J inbred mouse strains are useful models of low and high levels of juvenile sociability, respectively, but the neurobiological and developmental factors that account for the strains’ contrasting sociability levels are largely unknown. We hypothesized that BALB/cJ mice would show increasing sociability with age but that C57BL/6J mice would show high sociability throughout development. We also hypothesized that littermates would resemble one another in sociability more than non-littermates. Finally, we hypothesized that low sociability would be associated with low corpus callosum size and increased brain size in BALB/cJ mice. Separate cohorts of C57BL/6J and BALB/cJ mice were tested for sociability at 19-, 23-, 31-, 42-, or 70-days-of-age, and brain weights and mid-sagittal corpus callosum area were measured. BALB/cJ sociability increased with age, and a strain by age interaction in sociability between 31 and 42 days of age suggested strong effects of puberty on sociability development. Sociability scores clustered according to litter membership in both strains, and perinatal litter size and sex ratio were identified as factors that contributed to this clustering in C57BL/6J, but not BALB/cJ, litters. There was no association between corpus callosum size and sociability, but smaller brains were associated with lower sociability in BALB/cJ mice. The associations reported here will provide directions for future mechanistic studies of sociability development. PMID:22178318

  15. J SERIES MAGAZINE. J 107 SOUTH ELEVATION. Naval Magazine ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    J SERIES MAGAZINE. J 107 SOUTH ELEVATION. - Naval Magazine Lualualei, Headquarters Branch, Inert Storehouse Type, Twelfth Street between Kwajulein & New Mexico Streets, Pearl City, Honolulu County, HI

  16. Quantum Dense Coding About a Two-Qubit Heisenberg XYZ Model

    NASA Astrophysics Data System (ADS)

    Xu, Hui-Yun; Yang, Guo-Hui

    2017-09-01

    By taking into account the nonuniform magnetic field, the quantum dense coding with thermal entangled states of a two-qubit anisotropic Heisenberg XYZ chain are investigated in detail. We mainly show the different properties about the dense coding capacity ( χ) with the changes of different parameters. It is found that dense coding capacity χ can be enhanced by decreasing the magnetic field B, the degree of inhomogeneity b and temperature T, or increasing the coupling constant along z-axis J z . In addition, we also find χ remains the stable value as the change of the anisotropy of the XY plane Δ in a certain temperature condition. Through studying different parameters effect on χ, it presents that we can properly turn the values of B, b, J z , Δ or adjust the temperature T to obtain a valid dense coding capacity ( χ satisfies χ > 1). Moreover, the temperature plays a key role in adjusting the value of dense coding capacity χ. The valid dense coding capacity could be always obtained in the lower temperature-limit case.

  17. Sociability and brain development in BALB/cJ and C57BL/6J mice.

    PubMed

    Fairless, Andrew H; Dow, Holly C; Kreibich, Arati Sadalge; Torre, Matthew; Kuruvilla, Mariyam; Gordon, Elliot; Morton, Elizabeth A; Tan, Junhao; Berrettini, Wade H; Li, Hongzhe; Abel, Ted; Brodkin, Edward S

    2012-03-17

    Sociability--the tendency to seek social interaction--propels the development of social cognition and social skills, but is disrupted in autism spectrum disorders (ASD). BALB/cJ and C57BL/6J inbred mouse strains are useful models of low and high levels of juvenile sociability, respectively, but the neurobiological and developmental factors that account for the strains' contrasting sociability levels are largely unknown. We hypothesized that BALB/cJ mice would show increasing sociability with age but that C57BL/6J mice would show high sociability throughout development. We also hypothesized that littermates would resemble one another in sociability more than non-littermates. Finally, we hypothesized that low sociability would be associated with low corpus callosum size and increased brain size in BALB/cJ mice. Separate cohorts of C57BL/6J and BALB/cJ mice were tested for sociability at 19-, 23-, 31-, 42-, or 70-days-of-age, and brain weights and mid-sagittal corpus callosum area were measured. BALB/cJ sociability increased with age, and a strain by age interaction in sociability between 31 and 42 days of age suggested strong effects of puberty on sociability development. Sociability scores clustered according to litter membership in both strains, and perinatal litter size and sex ratio were identified as factors that contributed to this clustering in C57BL/6J, but not BALB/cJ, litters. There was no association between corpus callosum size and sociability, but smaller brains were associated with lower sociability in BALB/cJ mice. The associations reported here will provide directions for future mechanistic studies of sociability development. Copyright © 2011 Elsevier B.V. All rights reserved.

  18. DMRG study of the Kagome Antiferromagnetic Heisenberg Model

    NASA Astrophysics Data System (ADS)

    Yan, Simeng; White, Steven

    2010-03-01

    We have used DMRG to study the S=1/2 Heisenberg model on the Kagome lattice, using cylindrical boundary conditions and large clusters. We have focused on the spin gap and the presence or absence of the Valence Bond Crystal (VBC) order with a 36 unit cell as studied by Marston and Zeng, Singh and Huse, and others. Our results are probably the highest accuracy results for large clusters to date. Our extrapolated results find a finite spin gap with a value of about 0.05 J. To determine whether VBC order occurs, we calculated the ground states of a variety of clusters, some of which allow the 36 site VBC order, and others which do not allow it. For narrower cylinders (width < 12) , the VBC patterns are found to vanish as the number of kept states increases. For wider systems, we do observe VBC ground states, but it is not always clear that the calculations have converged. The extrapolated energies of the two types of states are very close, within about 1%.

  19. J-2X Turbopump Cavitation Diagnostics

    NASA Technical Reports Server (NTRS)

    Santi, I. Michael; Butas, John P.; Tyler, Thomas R., Jr.; Aguilar, Robert; Sowers, T. Shane

    2010-01-01

    The J-2X is the upper stage engine currently being designed by Pratt & Whitney Rocketdyne (PWR) for the Ares I Crew Launch Vehicle (CLV). Propellant supply requirements for the J-2X are defined by the Ares Upper Stage to J-2X Interface Control Document (ICD). Supply conditions outside ICD defined start or run boxes can induce turbopump cavitation leading to interruption of J-2X propellant flow during hot fire operation. In severe cases, cavitation can lead to uncontained engine failure with the potential to cause a vehicle catastrophic event. Turbopump and engine system performance models supported by system design information and test data are required to predict existence, severity, and consequences of a cavitation event. A cavitation model for each of the J-2X fuel and oxidizer turbopumps was developed using data from pump water flow test facilities at Pratt & Whitney Rocketdyne (PWR) and Marshall Space Flight Center (MSFC) together with data from Powerpack 1A testing at Stennis Space Center (SSC) and from heritage systems. These component models were implemented within the PWR J-2X Real Time Model (RTM) to provide a foundation for predicting system level effects following turbopump cavitation. The RTM serves as a general failure simulation platform supporting estimation of J-2X redline system effectiveness. A study to compare cavitation induced conditions with component level structural limit thresholds throughout the engine was performed using the RTM. Results provided insight into system level turbopump cavitation effects and redline system effectiveness in preventing structural limit violations. A need to better understand structural limits and redline system failure mitigation potential in the event of fuel side cavitation was indicated. This paper examines study results, efforts to mature J-2X turbopump cavitation models and structural limits, and issues with engine redline detection of cavitation and the use of vehicle-side abort triggers to augment the

  20. Half-magnetization plateau in a Heisenberg antiferromagnet on a triangular lattice

    NASA Astrophysics Data System (ADS)

    Ye, Mengxing; Chubukov, Andrey V.

    2017-10-01

    We present the phase diagram of a 2D isotropic triangular Heisenberg antiferromagnet in a magnetic field. We consider spin-S model with nearest-neighbor (J1) and next-nearest-neighbor (J2) interactions. We focus on the range of 1 /8 <J2/J1<1 , where the ordered states are different from those in the model with only nearest-neighbor exchange. A classical ground state in this range is infinitely degenerate in any field. The actual order is then determined by quantum fluctuations via "order from disorder" phenomenon. We argue that the phase diagram is rich due to competition between competing quantum states which break either orientational or sublattice symmetry. At small and high fields, the ground state is a canted stripe state, which breaks orientational symmetry, but at intermediate fields the ordered states break sublattice symmetry. The most noticeable of such states is "three up, one down" state in which spins in three sublattices are directed along the field and in one sublattice opposite to the field. In such a state, magnetization is quantized at exactly one half of the saturation value. We identify gapless states, which border the "three up, one down" state and discuss the transitions between these states and the canted stripe state.

  1. DEVELOPMENT OF HOME CAGE SOCIAL BEHAVIORS IN BALB/cJ vs. C57BL/6J MICE

    PubMed Central

    Fairless, Andrew H.; Katz, Julia M.; Vijayvargiya, Neha; Dow, Holly C.; Kreibich, Arati Sadalge; Berrettini, Wade H.; Abel, Ted; Brodkin, Edward S.

    2012-01-01

    BALB/cJ and C57BL/6J inbred mouse strains have been proposed as useful models of low and high levels of sociability (tendency to seek social interaction), respectively, based primarily on behaviors of ~30-day-old mice in the Social Approach Test (SAT). In the SAT, approach and sniffing behaviors of a test mouse toward an unfamiliar stimulus mouse are measured in a novel environment. However, it is unclear whether such results generalize to a familiar environment with a familiar social partner, such as with a littermate in a home cage environment. We hypothesized that C57BL/6J mice would show higher levels of social behaviors than BALB/cJ mice in the home cage environment, particularly at 30 days-of-age. We measured active and passive social behaviors in home cages by pairs of BALB/cJ or C57BL/6J littermates at ages 30, 41, and 69 days. The strains did not differ robustly in their active social behaviors. C57BL/6J mice were more passively social than BALB/cJ mice at 30 days, and C57BL/6J levels of passive social behaviors declined to BALB/cJ levels by 69 days. The differences in passive social behaviors at 30 days-of-age were primarily attributable to differences in huddling. These results indicate that different test conditions (SAT conditions vs. home cage conditions) elicit strain differences in distinct types of behaviors (approach/sniffing vs. huddling behaviors, respectively). Assessment of the more naturalistic social interactions in the familiar home cage environment with a familiar littermate will provide a useful component of a comprehensive assessment of social behaviors in mouse models relevant to autism. PMID:22982070

  2. Development of home cage social behaviors in BALB/cJ vs. C57BL/6J mice.

    PubMed

    Fairless, Andrew H; Katz, Julia M; Vijayvargiya, Neha; Dow, Holly C; Kreibich, Arati Sadalge; Berrettini, Wade H; Abel, Ted; Brodkin, Edward S

    2013-01-15

    BALB/cJ and C57BL/6J inbred mouse strains have been proposed as useful models of low and high levels of sociability (tendency to seek social interaction), respectively, based primarily on behaviors of ∼30-day-old mice in the Social Approach Test (SAT). In the SAT, approach and sniffing behaviors of a test mouse toward an unfamiliar stimulus mouse are measured in a novel environment. However, it is unclear whether such results generalize to a familiar environment with a familiar social partner, such as with a littermate in a home cage environment. We hypothesized that C57BL/6J mice would show higher levels of social behaviors than BALB/cJ mice in the home cage environment, particularly at 30 days-of-age. We measured active and passive social behaviors in home cages by pairs of BALB/cJ or C57BL/6J littermates at ages 30, 41, and 69 days. The strains did not differ robustly in their active social behaviors. C57BL/6J mice were more passively social than BALB/cJ mice at 30 days, and C57BL/6J levels of passive social behaviors declined to BALB/cJ levels by 69 days. The differences in passive social behaviors at 30 days-of-age were primarily attributable to differences in huddling. These results indicate that different test conditions (SAT conditions vs. home cage conditions) elicit strain differences in distinct types of behaviors (approach/sniffing vs. huddling behaviors, respectively). Assessment of the more naturalistic social interactions in the familiar home cage environment with a familiar littermate will provide a useful component of a comprehensive assessment of social behaviors in mouse models relevant to autism. Copyright © 2012 Elsevier B.V. All rights reserved.

  3. Comments on ""Lake Woebegone," Twenty Years Later" by J. J. Cannell, MD

    ERIC Educational Resources Information Center

    McRae, D. J.

    2006-01-01

    This article presents the author's comments on ""Lake Woebegone," Twenty Years Later" by J. J. Cannell, MD. J. J. Cannell's article on the so-called "Lake Woebegone" effect for K-12 educational testing systems is mostly an historical account of technical issues and policy considerations that led in part to development…

  4. High-Tc superconductivity: The t-J-V model and its applications

    NASA Astrophysics Data System (ADS)

    Roy, K.; Pal, P.; Nath, S.; Ghosh, N. K.

    2017-05-01

    We present numerical results of the t-J-V model in an 8-site tilted square cluster using exact diagonalization (ED) method with periodic boundary conditions. Effective hopping amplitude initially increases with inter-site Coulomb repulsion (V), but decreases at larger V's. The hole-hole correlation decreases with inter-site distances at smaller V. With the increase of Coulomb repulsion, the system becomes ordered. The specific heat curves confirm the non-Fermi liquid behavior of the system under t-J-V model.

  5. Nodal liquids in extended t-J models and dynamical supersymmetry

    NASA Astrophysics Data System (ADS)

    Mavromatos, Nick E.; Sarkar, Sarben

    2000-08-01

    In the context of extended t-J models, with intersite Coulomb interactions of the form -V∑j>ninj, with ni denoting the electron number operator at site i, nodal liquids are discussed. We use the spin-charge separation ansatz as applied to the nodes of a d-wave superconducting gap. Such a situation may be of relevance to the physics of high-temperature superconductivity. We point out the possibility of existence of certain points in the parameter space of the model characterized by dynamical supersymmetries between the spinon and holon degrees of freedom, which are quite different from the symmetries in conventional supersymmetric t-J models. Such symmetries pertain to the continuum effective-field theory of the nodal liquid, and one's hope is that the ancestor lattice model may differ from the continuum theory only by renormalization-group irrelevant operators in the infrared. We give plausible arguments that nodal liquids at such supersymmetric points are characterized by superconductivity of Kosterlitz-Thouless type. The fact that quantum fluctuations around such points can be studied in a controlled way, probably makes such systems of special importance for an eventual nonperturbative understanding of the complex phase diagram of the associated high-temperature superconducting materials.

  6. J SERIES MAGAZINE. J 107 SOUTH ELEVATION W/POLE. Naval ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    J SERIES MAGAZINE. J 107 SOUTH ELEVATION W/POLE. - Naval Magazine Lualualei, Headquarters Branch, Inert Storehouse Type, Twelfth Street between Kwajulein & New Mexico Streets, Pearl City, Honolulu County, HI

  7. J SERIES MAGAZINE. J 106 INTERIOR. BOMB TAILS ON LEFT. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    J SERIES MAGAZINE. J 106 INTERIOR. BOMB TAILS ON LEFT. - Naval Magazine Lualualei, Headquarters Branch, Inert Storehouse Type, Twelfth Street between Kwajulein & New Mexico Streets, Pearl City, Honolulu County, HI

  8. Phase separation in the t-J model. [in theory of high-temperature superconductors

    NASA Technical Reports Server (NTRS)

    Emery, V. J.; Lin, H. Q.; Kivelson, S. A.

    1990-01-01

    A detailed understanding of the motion of 'holes' in an antiferromagnet is of fundamental importance for the theory of high-temperature superconductors. It is shown here that, for the t-J model, dilute holes in an antiferromagnet are unstable against phase separation into a hole-rich and a no-hole phase. When the spin-exchange interaction J exceeds a critical value Jc, the hole-rich phase has no electrons. It is proposed that, for J slightly less than Jc, the hole-rich phase is a low-density superfluid of electron pairs. Phase separation in related models is briefly discussed.

  9. Study of J/ψ→pp̄ and J/ψ→nn̄

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ablikim, M.; Achasov, M. N.; Ambrose, D. J.

    2012-08-31

    The decays J/ψ→pp̄ and J/ψ→nn̄ have been investigated with a sample of 225.2×10⁶ J/ψ events collected with the BESIII detector at the BEPCII e⁺e⁻ collider. The branching fractions are determined to be B(J/ψ→pp̄)=(2.112±0.004±0.031)×10⁻³ and B(J/ψ→nn̄)=(2.07±0.01±0.17)×10⁻³. Distributions of the angle θ between the proton or antineutron and the beam direction are well described by the form 1+αcos²θ, and we find α=0.595±0.012±0.015 for J/ψ→pp̄ and α=0.50±0.04±0.21 for J/ψ→nn̄. Our branching-fraction results suggest a large phase angle between the strong and electromagnetic amplitudes describing the J/ψ→NN¯¯¯ decay.

  10. Ground state of a Heisenberg chain with next-nearest-neighbor bond alternation

    NASA Astrophysics Data System (ADS)

    Capriotti, Luca; Becca, Federico; Sorella, Sandro; Parola, Alberto

    2003-05-01

    We investigate the ground-state properties of the spin-half J1-J2 Heisenberg chain with a next-nearest-neighbor spin-Peierls dimerization using conformal field theory and Lanczos exact diagonalizations. In agreement with the results of a recent bosonization analysis by Sarkar and Sen [Phys. Rev. B 65, 172408 (2002)], we find that for small frustration (J2/J1) the system is in a Luttinger spin-fluid phase, with gapless excitations, and a finite spin-wave velocity. In the regime of strong frustration the ground state is spontaneously dimerized and the bond alternation reduces the triplet gap, leading to a slight enhancement of the critical point separating the Luttinger phase from the gapped one. An accurate determination of the phase boundary is obtained numerically from the study of the excitation spectrum.

  11. Hole pairing and thermodynamic properties of the two dimensional frustrated t-J model

    NASA Astrophysics Data System (ADS)

    Roy, K.; Pal, P.; Nath, S.; Ghosh, N. K.

    2018-04-01

    The frustrated t-J model is investigated by using the exact-diagonalization (ED) method on an 8-site cluster. The effect on next-nearest-neighbor (NNN) exchange interaction J' (frustration) on the hole pairing and the thermodynamic properties of the system is considered. Two holes initially remain unbound at smaller value of J'/t, but tend to bind at larger value. The maximum possibility of pair formation has been observed to be at NNN sites. Entropy calculation shows that the system goes to more disordered state with J'. The specific heat curves show a single peak structure. A decrease in effective exchange energy is observed due to the frustration.

  12. The effect of dietary fat intake on hepatic gene expression in LG/J AND SM/J mice

    PubMed Central

    2014-01-01

    Background The liver plays a major role in regulating metabolic homeostasis and is vital for nutrient metabolism. Identifying the genetic factors regulating these processes could lead to a greater understanding of how liver function responds to a high-fat diet and how that response may influence susceptibilities to obesity and metabolic syndrome. In this study we examine differences in hepatic gene expression between the LG/J and SM/J inbred mouse strains and how gene expression in these strains is affected by high-fat diet. LG/J and SM/J are known to differ in their responses to a high-fat diet for a variety of obesity- and diabetes-related traits, with the SM/J strain exhibiting a stronger phenotypic response to diet. Results Dietary intake had a significant effect on gene expression in both inbred lines. Genes up-regulated by a high-fat diet were involved in biological processes such as lipid and carbohydrate metabolism; protein and amino acid metabolic processes were down regulated on a high-fat diet. A total of 259 unique transcripts exhibited a significant diet-by-strain interaction. These genes tended to be associated with immune function. In addition, genes involved in biochemical processes related to non-alcoholic fatty liver disease (NAFLD) manifested different responses to diet between the two strains. For most of these genes, SM/J had a stronger response to the high-fat diet than LG/J. Conclusions These data show that dietary fat impacts gene expression levels in SM/J relative to LG/J, with SM/J exhibiting a stronger response. This supports previous data showing that SM/J has a stronger phenotypic response to high-fat diet. Based upon these findings, we suggest that SM/J and its cross with the LG/J strain provide a good model for examining non-alcoholic fatty liver disease and its role in metabolic syndrome. PMID:24499025

  13. Inclusive J / $$\\psi$$ Production at D0

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Murphy, Christopher R.

    1995-04-01

    We present results on inclusivemore » $$J/\\psi$$ and b-quark production in $$p\\bar{p}$$ collisions at $$\\sqrt{s}$$ = 1.8 TeV. The results are based on data collected at the D0 experiment during the 1992-1993 FermiLab collider run. There is excellent agreement between the differential $$J/\\psi$$ cross section measured at D0 and that measured at the CDF detector. A measurement of the fraction of $$J/\\psi$$ events due to b-quark decays is presented and we extract from this a measurement of the integrated b-quark cross section. The radiative decays of $$_{Xc}$$ charmonium states into the $$J/\\psi$$ is discussed and we present results on the fraction of $$J/\\psi$$ mesons that are due to $$_{Xc}$$ decays. We also observe that a fraction of promptly produced $$J/\\psi$$ mesons is larger than the measured fraction of $$J/\\psi$$ due to $$_{Xc}$$ decays and is not accounted for by existing charmonium. production models.« less

  14. Bacillus subtilis ribonucleases J1 and J2 form a complex with altered enzyme behaviour.

    PubMed

    Mathy, Nathalie; Hébert, Agnès; Mervelet, Peggy; Bénard, Lionel; Dorléans, Audrey; Li de la Sierra-Gallay, Inés; Noirot, Philippe; Putzer, Harald; Condon, Ciarán

    2010-01-01

    Ribonucleases J1 and J2 are recently discovered enzymes with dual 5'-to-3' exoribonucleolytic/endoribonucleolytic activity that plays a key role in the maturation and degradation of Bacillus subtilis RNAs. RNase J1 is essential, while its paralogue RNase J2 is not. Up to now, it had generally been assumed that the two enzymes functioned independently. Here we present evidence that RNases J1 and J2 form a complex that is likely to be the predominant form of these enzymes in wild-type cells. While both RNase J1 and the RNase J1/J2 complex have robust 5'-to-3' exoribonuclease activity in vitro, RNase J2 has at least two orders of magnitude weaker exonuclease activity, providing a possible explanation for why RNase J1 is essential. The association of the two proteins also has an effect on the endoribonucleolytic properties of RNases J1 and J2. While the individual enzymes have similar endonucleolytic cleavage activities and specificities, as a complex they behave synergistically to alter cleavage site preference and to increase cleavage efficiency at specific sites. These observations dramatically change our perception of how these ribonucleases function and provide an interesting example of enzyme subfunctionalization after gene duplication.

  15. Evidence for a gapped spin-liquid ground state in a kagome Heisenberg antiferromagnet

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fu, Mingxuan; Imai, Takahashi; Han, Tian -Heng

    2015-11-06

    Here, the kagome Heisenberg antiferromagnet is a leading candidate in the search for a spin system with a quantum spin-liquid ground state. The nature of its ground state remains a matter of active debate. We conducted oxygen-17 single-crystal nuclear magnetic resonance (NMR) measurements of the spin-1/2 kagome lattice in herbertsmithite [ZnCu 3(OH) 6Cl 2], which is known to exhibit a spinon continuum in the spin excitation spectrum. We demonstrated that the intrinsic local spin susceptibility χkagome, deduced from the oxygen-17 NMR frequency shift, asymptotes to zero below temperatures of 0.03J, where J ~ 200 kelvin is the copper-copper superexchange interaction.more » Combined with the magnetic field dependence of χ kagome that we observed at low temperatures, these results imply that the kagome Heisenberg antiferromagnet has a spin-liquid ground state with a finite gap.« less

  16. 5-HT(2C) receptor RNA editing in the amygdala of C57BL/6J, DBA/2J, and BALB/cJ mice.

    PubMed

    Hackler, Elizabeth A; Airey, David C; Shannon, Caitlin C; Sodhi, Monsheel S; Sanders-Bush, Elaine

    2006-05-01

    Post-transcriptional RNA editing of the G-protein coupled 5-hydroxytryptamine-2C (5-HT(2C)) receptor predicts an array of 24 receptor isoforms, some of which are characterized by reduced constitutive activity and potency to initiate intracellular signaling. The amygdala is integral to anxiety, fear, and related psychiatric diseases. Activation of 5-HT(2C) receptors within the amygdala is anxiogenic. Here, we describe the RNA editing profiles from amygdala of two inbred mouse strains (BALB/cJ and DBA/2J) known to be more anxious than a third (C57BL/6J). We confirmed the strain anxiety differences using light<-->dark exploration, and we discovered that BALB/cJ and DBA/2J are each characterized by a higher functioning RNA editing profile than C57BL/6J. BALB/cJ and DBA/2J exhibit a roughly two-fold reduction in C site editing, and a corresponding two-fold reduction in the edited isoform VSV. C57BL/6J is characterized by a relative decrease in the unedited highly functional isoform INI. We estimated the heritability of editing at the C site to be approximately 40%. By sequencing genomic DNA, we found complete conservation between C57BL/6J, BALB/cJ, DBA/2J and 37 other inbred strains for the RNA edited region of Htr2c, suggesting Htr2c DNA sequence does not influence variation in Htr2c RNA editing between inbred strains of mice. We did, however, discover that serotonin turnover is reduced in BALB/cJ and DBA/2J, consistent with emerging evidence that synaptic serotonin levels regulate RNA editing. These results encourage further study of the causes and consequences of 5-HT(2C) receptor RNA editing in the amygdala of mice.

  17. Unified molecular field theory for collinear and noncollinear Heisenberg antiferromagnets

    NASA Astrophysics Data System (ADS)

    Johnston, David C.

    2015-02-01

    A unified molecular field theory (MFT) is presented that applies to both collinear and planar noncollinear Heisenberg antiferromagnets (AFs) on the same footing. The spins in the system are assumed to be identical and crystallographically equivalent. This formulation allows calculations of the anisotropic magnetic susceptibility χ versus temperature T below the AF ordering temperature TN to be carried out for arbitrary Heisenberg exchange interactions Ji j between arbitrary neighbors j of a given spin i without recourse to magnetic sublattices. The Weiss temperature θp in the Curie-Weiss law is written in terms of the Ji j values and TN in terms of the Ji j values and an assumed AF structure. Other magnetic and thermal properties are then expressed in terms of quantities easily accessible from experiment as laws of corresponding states for a given spin S . For collinear ordering these properties are the reduced temperature t =T /TN , the ratio f =θp/TN , and S . For planar noncollinear helical or cycloidal ordering, an additional parameter is the wave vector of the helix or cycloid. The MFT is also applicable to AFs with other AF structures. The MFT predicts that χ (T ≤TN) of noncollinear 120∘ spin structures on triangular lattices is isotropic and independent of S and T and thus clarifies the origin of this universally observed behavior. The high-field magnetization and heat capacity for fields applied perpendicular to the ordering axis (collinear AFs) and ordering plane (planar noncollinear AFs) are also calculated and expressed for both types of AF structures as laws of corresponding states for a given S , and the reduced perpendicular field versus reduced temperature phase diagram is constructed.

  18. J Waves for Predicting Cardiac Events in Hypertrophic Cardiomyopathy.

    PubMed

    Tsuda, Toyonobu; Hayashi, Kenshi; Konno, Tetsuo; Sakata, Kenji; Fujita, Takashi; Hodatsu, Akihiko; Nagata, Yoji; Teramoto, Ryota; Nomura, Akihiro; Tanaka, Yoshihiro; Furusho, Hiroshi; Takamura, Masayuki; Kawashiri, Masa-Aki; Fujino, Noboru; Yamagishi, Masakazu

    2017-10-01

    This study sought to investigate whether the presence of J waves was associated with cardiac events in patients with hypertrophic cardiomyopathy (HCM). It has been uncertain whether the presence of J waves predicts life-threatening cardiac events in patients with HCM. This study evaluated consecutive 338 patients with HCM (207 men; age 61 ± 17 years of age). A J-wave was defined as J-point elevation >0.1 mV in at least 2 contiguous inferior and/or lateral leads. Cardiac events were defined as sudden cardiac death, ventricular fibrillation or sustained ventricular tachycardia, or appropriate implantable cardiac defibrillator therapy. The study also investigated whether adding the J-wave in a conventional risk model improved a prediction of cardiac events. J waves were seen in 46 (13.6%) patients at registration. Cardiac events occurred in 31 patients (9.2%) during median follow-up of 4.9 years (interquartile range: 2.6 to 7.1 years). In a Cox proportional hazards model, the presence of J waves was significantly associated with cardiac events (adjusted hazard ratio: 4.01; 95% confidence interval [CI]: 1.78 to 9.05; p = 0.001). Compared with the conventional risk model, the model using J waves in addition to conventional risks better predicted cardiac events (net reclassification improvement, 0.55; 95% CI: 0.20 to 0.90; p = 0.002). The presence of J waves was significantly associated with cardiac events in HCM. Adding J waves to conventional cardiac risk factors improved prediction of cardiac events. Further confirmatory studies are needed before considering J-point elevation as a marker of risk for use in making management decisions regarding risk in patients with HCM. Copyright © 2017 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

  19. Novel object exploration in the C58/J mouse model of autistic-like behavior.

    PubMed

    Blick, Mikkal G; Puchalski, Breann H; Bolanos, Veronica J; Wolfe, Kaitlin M; Green, Matthew C; Ryan, Bryce C

    2015-04-01

    Mouse models of autistic like behaviors are a valuable tool to use when studying the causes, symptoms, and potential treatments for autism. The inbred C58/J strain is a strain of interest for this model and has previously been shown to possess face validity for some of the core traits of autism, including low social behavior and elevated motor stereotypies. Higher order repetitive behaviors have not been extensively studied in this strain, or in mice in general. In this study, we looked for evidence of higher-order repetitive behaviors in the C58/J strain using a novel object assay. This assay utilized a mouse's natural exploratory behavior among unfamiliar objects to identify potential sequencing patterns in motor activity. The motor stereotypies displayed by the C58/J strain during testing were consistent with past studies. The C58/J strain also displayed a high preference for a single object in the round arena assays and the females demonstrating elevated sequencing patterns in the round arena. Although the C58/J strain did not show pervasive evidence of higher-order repetitive behaviors across all measures, there was evidence of higher order repetitive behaviors in certain situations. This study further demonstrates the potential of the C58/J mouse strains as a model for lower-order and potentially, higher-order repetitive behaviors. This study also demonstrates that the shape of the novel object arena can change the behavior displayed by the test animals. Further studies utilizing the C58/J strain and further validation of the novel object assay are warranted. Copyright © 2014 Elsevier B.V. All rights reserved.

  20. I Dream of J.J., or Affordances and Motion Pictures.

    ERIC Educational Resources Information Center

    Anderson, Joseph D.

    1995-01-01

    Categorizes attempts to account for how viewers garner meanings from motion pictures as either semiotic, realist, or conventionalist. Proposes an alternative explanation based on J. J. Gibson's ecological theory of perception. Offers his concept of "affordances" as the key to an explanation of how meanings in motion pictures are…

  1. jà Experiences in Temporal Lobe Epilepsy

    PubMed Central

    Illman, Nathan A.; Butler, Chris R.; Souchay, Celine; Moulin, Chris J. A.

    2012-01-01

    Historically, déjà vu has been linked to seizure activity in temporal lobe epilepsy, and clinical reports suggest that many patients experience the phenomenon as a manifestation of simple partial seizures. We review studies on déjà vu in epilepsy with reference to recent advances in the understanding of déjà vu from a cognitive and neuropsychological standpoint. We propose a decoupled familiarity hypothesis, whereby déjà vu is produced by an erroneous feeling of familiarity which is not in keeping with current cognitive processing. Our hypothesis converges on a parahippocampal dysfunction as the locus of déjà vu experiences. However, several other temporal lobe structures feature in reports of déjà vu in epilepsy. We suggest that some of the inconsistency in the literature derives from a poor classification of the various types of déjà experiences. We propose déjà vu/déjà vécu as one way of understanding déjà experiences more fully. This distinction is based on current models of memory function, where déjà vu is caused by erroneous familiarity and déjà vécu by erroneous recollection. Priorities for future research and clinical issues are discussed. PMID:22957231

  2. jà experiences in temporal lobe epilepsy.

    PubMed

    Illman, Nathan A; Butler, Chris R; Souchay, Celine; Moulin, Chris J A

    2012-01-01

    Historically, déjà vu has been linked to seizure activity in temporal lobe epilepsy, and clinical reports suggest that many patients experience the phenomenon as a manifestation of simple partial seizures. We review studies on déjà vu in epilepsy with reference to recent advances in the understanding of déjà vu from a cognitive and neuropsychological standpoint. We propose a decoupled familiarity hypothesis, whereby déjà vu is produced by an erroneous feeling of familiarity which is not in keeping with current cognitive processing. Our hypothesis converges on a parahippocampal dysfunction as the locus of déjà vu experiences. However, several other temporal lobe structures feature in reports of déjà vu in epilepsy. We suggest that some of the inconsistency in the literature derives from a poor classification of the various types of déjà experiences. We propose déjà vu/déjà vécu as one way of understanding déjà experiences more fully. This distinction is based on current models of memory function, where déjà vu is caused by erroneous familiarity and déjà vécu by erroneous recollection. Priorities for future research and clinical issues are discussed.

  3. Photolysis rates in correlated overlapping cloud fields: Cloud-J 7.3

    DOE PAGES

    Prather, M. J.

    2015-05-27

    A new approach for modeling photolysis rates ( J values) in atmospheres with fractional cloud cover has been developed and implemented as Cloud-J – a multi-scattering eight-stream radiative transfer model for solar radiation based on Fast-J. Using observed statistics for the vertical correlation of cloud layers, Cloud-J 7.3 provides a practical and accurate method for modeling atmospheric chemistry. The combination of the new maximum-correlated cloud groups with the integration over all cloud combinations represented by four quadrature atmospheres produces mean J values in an atmospheric column with root-mean-square errors of 4% or less compared with 10–20% errors using simpler approximations.more » Cloud-J is practical for chemistry-climate models, requiring only an average of 2.8 Fast-J calls per atmosphere, vs. hundreds of calls with the correlated cloud groups, or 1 call with the simplest cloud approximations. Another improvement in modeling J values, the treatment of volatile organic compounds with pressure-dependent cross sections is also incorporated into Cloud-J.« less

  4. Transient simulation of a miniature Joule-Thomson (J-T) cryocooler with and without the distributed J-T effect

    NASA Astrophysics Data System (ADS)

    Damle, R. M.; Atrey, M. D.

    2015-01-01

    The aim of this work is to develop a transient program for the simulation of a miniature Joule-Thomson (J-T) cryocooler to predict its cool-down characteristics. A one dimensional transient model is formulated for the fluid streams and the solid elements of the recuperative heat exchanger. Variation of physical properties due to pressure and temperature is considered. In addition to the J-T expansion at the end of the finned tube, the distributed J-T effect along its length is also considered. It is observed that the distributed J-T effect leads to additional cooling of the gas in the finned tube and that it cannot be neglected when the pressure drop along the length of the finned tube is large. The mathematical model, method of resolution and the global transient algorithm, within a modular object-oriented framework, are detailed in this paper. As a part of verification and validation of the developed model, cases available in the literature are simulated and the results are compared with the corresponding numerical and experimental data.

  5. Is the CMS e e j j excess a hint for light supersymmetry?

    NASA Astrophysics Data System (ADS)

    Krauss, Manuel E.; Porod, Werner

    2015-09-01

    We discuss the impact of additional two-body decays of the right-handed neutrino into a light charged Higgs state on the dilepton plus dijet cross sections from resonant W' production. We consider in particular a supersymmetric left-right symmetric model which predicts such a light charged Higgs boson. We demonstrate that the e e j j excess as measured by CMS can be explained best if the W' also has decay modes into Higgsino-like charginos and neutralinos with masses of a few hundred GeV. Provided that this excess is confirmed, the model predicts also one right-handed neutrino with a mass below 200 GeV as well as a doubly charged Higgs boson which should be discovered at the LHC in the near future.

  6. DETAIL OF CORNERSTONE, WHICH STATES "J.J. DANIELS, BUILDER 1861." NOTE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL OF CORNERSTONE, WHICH STATES "J.J. DANIELS, BUILDER 1861." NOTE ALSO IRON STRAP AT EAST CORNER OF ABUTMENT. - Jackson Covered Bridge, Spanning Sugar Creek, CR 775N (Changed from Spanning Sugar Creek), Bloomingdale, Parke County, IN

  7. Control of Expression of the RNases J1 and J2 in Bacillus subtilis

    PubMed Central

    Jamalli, Ailar; Hébert, Agnès; Zig, Léna

    2014-01-01

    In Bacillus subtilis, the dual activity 5′ exo- and endoribonucleases J1 and J2 are important players in mRNA and stable RNA maturation and degradation. Recent work has improved our understanding of their structure and mechanism of action and identified numerous RNA substrates. However, almost nothing is known about the expression of these enzymes. Here, we have identified the transcriptional and translational signals that control the expression of the rnjA (RNase J1) and rnjB (RNase J2) genes. While the rnjB gene is transcribed constitutively from a sigma A promoter, optimal expression of RNase J1 requires cotranscription and cotranslation with the upstream ykzG gene, encoding a protein of unknown function. In the absence of coupled translation, RNase J1 expression is decreased more than 5-fold. Transcription of the ykzG operon initiates at a sigma A promoter with a noncanonical −35 box that is required for optimal transcription. Biosynthesis of RNase J1 is autocontrolled within a small range (1.4-fold) and also slightly stimulated (1.4-fold) in the absence of RNase J2. These controls are weak but might be useful to maintain the overall RNase J level and possibly also equimolar amounts of the two nucleases in the cell that primarily act as a heterodimer in vivo. PMID:24187087

  8. jFuzz: A Concolic Whitebox Fuzzer for Java

    NASA Technical Reports Server (NTRS)

    Jayaraman, Karthick; Harvison, David; Ganesh, Vijay; Kiezun, Adam

    2009-01-01

    We present jFuzz, a automatic testing tool for Java programs. jFuzz is a concolic whitebox fuzzer, built on the NASA Java PathFinder, an explicit-state Java model checker, and a framework for developing reliability and analysis tools for Java. Starting from a seed input, jFuzz automatically and systematically generates inputs that exercise new program paths. jFuzz uses a combination of concrete and symbolic execution, and constraint solving. Time spent on solving constraints can be significant. We implemented several well-known optimizations and name-independent caching, which aggressively normalizes the constraints to reduce the number of calls to the constraint solver. We present preliminary results due to the optimizations, and demonstrate the effectiveness of jFuzz in creating good test inputs. The source code of jFuzz is available as part of the NASA Java PathFinder. jFuzz is intended to be a research testbed for investigating new testing and analysis techniques based on concrete and symbolic execution. The source code of jFuzz is available as part of the NASA Java PathFinder.

  9. J-tube technique for double-j stent insertion during laparoscopic upper urinary tract surgical procedures.

    PubMed

    Kim, Hyung Suk; Lee, Byung Ki; Jung, Jin-Woo; Lee, Jung Keun; Byun, Seok-Soo; Lee, Sang Eun; Jeong, Chang Wook

    2014-11-01

    Double-J stent insertion has been generally performed during laparoscopic upper urinary tract (UUT) surgical procedures to prevent transient urinary tract obstruction and postoperative flank pain from ureteral edema and blood clots. Several restrictive conditions that make this procedure difficult and time consuming, however, include the coiled distal ends of the flexible Double-J stent and the limited bending angle of the laparoscopic instruments. To overcome these limitations, we devised a Double-J stent insertion method using the new J-tube technique. Between July 2011 and May 2013, Double-J stents were inserted using the J-tube technique in 33 patients who underwent a laparoscopic UUT surgical procedure by a single surgeon. The mean stent placement time was 4.8±2.7 minutes, and there were no intraoperative complications. In conclusion, the J-tube technique is a safe and time-saving method for Double-J stent insertion during laparoscopic surgical procedures.

  10. Optimizing Crawler4j using MapReduce Programming Model

    NASA Astrophysics Data System (ADS)

    Siddesh, G. M.; Suresh, Kavya; Madhuri, K. Y.; Nijagal, Madhushree; Rakshitha, B. R.; Srinivasa, K. G.

    2017-06-01

    World wide web is a decentralized system that consists of a repository of information on the basis of web pages. These web pages act as a source of information or data in the present analytics world. Web crawlers are used for extracting useful information from web pages for different purposes. Firstly, it is used in web search engines where the web pages are indexed to form a corpus of information and allows the users to query on the web pages. Secondly, it is used for web archiving where the web pages are stored for later analysis phases. Thirdly, it can be used for web mining where the web pages are monitored for copyright purposes. The amount of information processed by the web crawler needs to be improved by using the capabilities of modern parallel processing technologies. In order to solve the problem of parallelism and the throughput of crawling this work proposes to optimize the Crawler4j using the Hadoop MapReduce programming model by parallelizing the processing of large input data. Crawler4j is a web crawler that retrieves useful information about the pages that it visits. The crawler Crawler4j coupled with data and computational parallelism of Hadoop MapReduce programming model improves the throughput and accuracy of web crawling. The experimental results demonstrate that the proposed solution achieves significant improvements with respect to performance and throughput. Hence the proposed approach intends to carve out a new methodology towards optimizing web crawling by achieving significant performance gain.

  11. Determination of the number of J/ψ events with inclusive J/ψ decays

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ablikim, M.; Achasov, M. N.; Ai, X. C.

    A measurement of the number of J/ψ events collected with the BESIII detector in 2009 and 2012 is performed using inclusive decays of the J/ψ. The number of J/ψ events taken in 2009 is recalculated to be (223.7 ± 1.4) × 10 6, which is in good agreement with the previous measurement, but with significantly improved precision due to improvements in the BESIII software. The number of J/ψ events taken in 2012 is determined to be (1086.9 ± 6.0) × 10 6. In total, the number of J/ψ events collected with the BESIII detector is measured to be (1310.6 ±more » 7.0) × 10 6, where the uncertainty is dominated by systematic effects and the statistical uncertainty is negligible.« less

  12. Determination of the number of J/ψ events with inclusive J/ψ decays

    DOE PAGES

    Ablikim, M.; Achasov, M. N.; Ai, X. C.; ...

    2016-08-26

    A measurement of the number of J/ψ events collected with the BESIII detector in 2009 and 2012 is performed using inclusive decays of the J/ψ. The number of J/ψ events taken in 2009 is recalculated to be (223.7 ± 1.4) × 10 6, which is in good agreement with the previous measurement, but with significantly improved precision due to improvements in the BESIII software. The number of J/ψ events taken in 2012 is determined to be (1086.9 ± 6.0) × 10 6. In total, the number of J/ψ events collected with the BESIII detector is measured to be (1310.6 ±more » 7.0) × 10 6, where the uncertainty is dominated by systematic effects and the statistical uncertainty is negligible.« less

  13. The branching fraction calculations of Bc+ → ψ(2S)π+, Bc+ → J/ψK+ and Bc+ → J/ψDs+ decays relative to that of the Bc+ → J/ψπ+ mode

    NASA Astrophysics Data System (ADS)

    Mohammadi, Behnam

    2018-03-01

    The weak decay of Bc+ into ψ(2S)π+, J/ψK+ and J/ψDs+ mesons, observed by LHCb collaboration for the first time, are calculated in the model which takes into account the “factorizable” contributions and “nonfactorizable” corrections. The decays of Bc+ mesons into charmonia and light hadrons are expected to be well described by the factorization approximation. In the standard model, Bc+ → ψ(2S)π+, J/ψK+ decays occur through only the tree-level diagrams and so there are no CP violation in these channels. The decay Bc+ → ψ(2S)π+ is expected to proceed mainly via a b¯ →c¯ud¯ transition because the Bc+ → J/ψπ+ decay has identical final state and similar event topology, where it is chosen as the relative branching fraction channel. The ratio of branching fractions ℬ(Bc+ → J/ψK+)/ℬ(B c+ → J/ψπ+) is of particular interest since the CKM matrix element is suppressed by a factor |Vus/Vud|2 ˜ 0.05, in which the Bc+ → J/ψK+ occur through b¯ →c¯us¯ transition, but the dominant amplitude of the decay Bc+ → J/ψπ+ is a b¯ →c¯ud¯ transition. The decay Bc+ → J/ψD s+ is examined by color-allowed, color-suppressed spectator and weak annihilation diagrams. The weak annihilation topology, in contrast to decays of other beauty hadrons, is not suppressed and can contribute significantly to the decay amplitude. Because of the Bc+ → ψ(2S)π+, Bc+ → J/ψK+ and Bc+ → J/ψD s+ branching fractions are calculated relative to the Bc+ → J/ψπ+ decay, this decay mode is estimated separately, the ratio between them are 0.327 ± 0.028, 0.074 ± 0.0057 and 3.257 ± 0.293, respectively, that are compatible with the experimental data.

  14. Investigation of the chiral antiferromagnetic Heisenberg model using projected entangled pair states

    NASA Astrophysics Data System (ADS)

    Poilblanc, Didier

    2017-09-01

    A simple spin-1/2 frustrated antiferromagnetic Heisenberg model (AFHM) on the square lattice—including chiral plaquette cyclic terms—was argued [A. E. B. Nielsen, G. Sierra, and J. I. Cirac, Nat. Commun. 4, 2864 (2013), 10.1038/ncomms3864] to host a bosonic Kalmeyer-Laughlin (KL) fractional quantum Hall ground state [V. Kalmeyer and R. B. Laughlin, Phys. Rev. Lett. 59, 2095 (1987), 10.1103/PhysRevLett.59.2095]. Here, we construct generic families of chiral projected entangled pair states (chiral PEPS) with low bond dimension (D =3 ,4 ,5 ) which, upon optimization, provide better variational energies than the KL Ansatz. The optimal D =3 PEPS exhibits chiral edge modes described by the Wess-Zumino-Witten SU(2) 1 model, as expected for the KL spin liquid. However, we find evidence that, in contrast to the KL state, the PEPS spin liquids have power-law dimer-dimer correlations and exhibit a gossamer long-range tail in the spin-spin correlations. We conjecture that these features are genuine to local chiral AFHM on bipartite lattices.

  15. The congenic normal R/APfd and jaundiced R/APfd-j/j rat strains: a new animal model of hereditary non-haemolytic unconjugated hyperbilirubinaemia due to defective bilirubin conjugation.

    PubMed

    Leyten, R; Vroemen, J P; Blanckaert, N; Heirwegh, K P

    1986-10-01

    In this paper the production of the R/APfd-j/j strain which is congenic with the R/APfd strain is reported. The R/APfd-j/j completely lacks hepatic bilirubin UDP-glucuronyltransferase activity, as do our GUNNXR/Pfd-j/j rat strain and various other stocks of GUNN rats (j/j) described in the literature. Our recombinant inbred strain GUNNXR/Pfd-j/j was produced from non-inbred GUNN (j/j) rats. This GUNNXR/Pfd-j/j rat was used as a donor of the jaundice gene j, the R/APfd rat serving as the recipient. After eight backcross-intercross cycles (16 generations) the R/APfd-j/j strain was obtained which is congenic with the R/APfd strain. Congenicity was demonstrated by various techniques including transplantation of skin tissue, strain-specific tumour cells and hepatocytes, the mixed lymphocyte reaction, and comparison of biochemical markers. The potential of the novel inbred strain of jaundiced rat, R/APfd-j/j, and the corresponding control strain R/APfd for biochemical and clinical studies of bilirubin metabolism are briefly discussed.

  16. Searching for planetary nebulae at the Galactic halo via J-PAS and J-PLUS

    NASA Astrophysics Data System (ADS)

    Goncalves, Denise R.; Aparício-Villegas, Teresa; Akras, Stavros; Borges Fernandes, Marcelo; J-PAS Collaboration

    2015-08-01

    The Javalambre-Physics of the Accelerating Universe Astrophysical Survey (J-PAS) is a narrow-band imaging, very wide field cosmological survey to be carried out from a dedicated 2.5m telescope and a 4.7 sq.deg camera with 1.2Gpix. It will last 5 years and will observe 8500 sq.deg of Northern sky to a 5-σ magnitude depth for point sources, equivalent to i ~23.3 over an aperture of 2 arcsec2. The J-PAS filter system consists of 54 contiguous narrow band filters of 145-Å FWHM, from 3,500 to 10,000Å. Two broad-band filters will be added at the extremes, UV and IR, plus 3 SDSS g, r, and i filters. The Javalambre Photometric Local Universe Survye (J-PLUS) will be an auxiliary survey ofJ-PAS (mainly for calibration) with a dedicated 0.80m telescope. J-PLUS comprises 12 filters, including g, r, i and z SDSS ones. Though about 2,500 planetary nebulae (PNe, confirmed spectroscopically) are known in the Galaxy, only 14 objects have been convincingly identified as halo PNe. They were classified as such from their location, kinematics and chemistry. Halo PNe are able to reveal precious information for the study of low- and intermediate-mass star evolution and the early chemical conditions of the Galaxy. The characteristic low continuum and intense line emissions of PNe make them good objects to be searched by J-PAS, and even by J-PLUS. For instance, the halo PNe BoBn 1, DdDm 1 and PS 1, located somewhere between 11 and 24 kpc from the Sun, have B magnitudes of 16, 14 and 13.4, respectively. Such values are easily encompassed by J-PAS/J-PLUS, given the typical limit magnitude of the survey. Though covering a significantly smaller sky area, data from the ALHAMBRA survey were used to test our J-PAS/J-PLUS strategy to search for PNe. Our first results will be shown in this poster.

  17. Vertical transmission of avian leukosis virus subgroup J (ALV-J) from hens infected through artificial insemination with ALV-J infected semen.

    PubMed

    Li, Yang; Cui, Shuai; Li, Weihua; Wang, Yixin; Cui, Zhizhong; Zhao, Peng; Chang, Shuang

    2017-06-29

    Avian leukosis virus (ALV) is one of the main causes of tumour development within the poultry industry in China. The subgroup J avian leukosis viruses (ALV-J), which induce erythroblastosis and myelocytomatosis, have the greatest pathogenicity and transmission ability within this class of viruses. ALV can be transmitted both horizontally and vertically; however, the effects of ALV infection in chickens-especially roosters-during the propagation, on future generations is not clear. Knowing the role of the cock in the transmission of ALV from generation to generation might contribute to the eradication programs for ALV. The results showed that two hens inseminated with ALV-J-positive semen developed temporary antibody responses to ALV-J at 4-5 weeks post insemination. The p27 antigen was detected in cloacal swabs of six hens, and in 3 of 26 egg albumens at 1-6 weeks after insemination. Moreover, no viremia was detected at 6 weeks after insemination even when virus isolation had been conducted six times at weekly intervals for each of the 12 females. However, ALV-J was isolated from 1 of their 34 progeny chicks at 1 week of age, and its gp85 had 98.4%-99.2% sequence identity with the gp85 of ALV-J isolated from semen samples of the six cocks. Our findings indicated that females that were late horizontally infected with ALV-J by artificial insemination might transmit the virus to progeny through eggs, which amounts to vertical transmission.

  18. Nova Sco 2011 No. 2 = PNV J16364440-4132340 = PNV J16364300-4132460

    NASA Astrophysics Data System (ADS)

    Waagen, Elizabeth O.

    2011-09-01

    Announcement of discovery of Nova Sco 2011 No. 2 = PNV J16364440-4132340 = PNV J16364300-4132460. Discovered independently by John Seach (Chatsworth Island, NSW, Australia, on 2011 Sep. 06.37 UT at mag=9.8 (DSLR)) and by Yuji Nakamura (Kameyama, Mie, Japan, on 2011 Sep. 06.4313 UT at mag=9.7 C (CCD)). Posted on the IAU Central Bureau for Astronomical Telegrams Transient Object Confirmation Page (TOCP) as PNV J16364440-4132340 (Nakamura) and PNV J16364300-4132460 (Seach); identifications consolidated in VSX under PNV J16364440-4132340. Spectra obtained by A. Arai et al. on 2011 Sep. 7.42 UT suggest a highly reddened Fe II-type classical nova. Spectra by F. Walter and J. Seron obtained Sep. 2011 8.091 UT confirm a young galactic nova; they report spectra are reminiscent of an early recurrent nova. Initially announced in AAVSO Special Notice #251 (Matthew Templeton) and IAU Central Bureau Electronic Telegram 2813 (Daniel W. E. Green, ed.). Finder charts with sequence may be created using the AAVSO Variable Star Plotter (http://www.aavso.org/vsp). Observations should be submitted to the AAVSO International Database. See full Alert Notice for more details and observations.

  19. Transverse Single Spin Asymmetry in \\varvec{J}/\\varvec{ψ } Production

    NASA Astrophysics Data System (ADS)

    Sonawane, Bipin; Misra, Anuradha; Padval, Siddhesh; Rawoot, Vaibhav

    2018-05-01

    We estimate transverse single spin asymmetry (TSSA) in electroproduction of J/ψ for J-Lab and EIC energies. We present estimates of TSSAs in J/ψ production within generalized parton model (GPM) using recent parametrizations of gluon Sivers function (GSF) and compare the results obtained using color singlet model (CSM) with those obtained using color evaporation model (CEM) of quarkonium production.

  20. Branching fraction measurement of J /ψ →KSKL and search for J /ψ →KSKS

    NASA Astrophysics Data System (ADS)

    Ablikim, M.; Achasov, M. N.; Ahmed, S.; Albrecht, M.; Alekseev, M.; Amoroso, A.; An, F. F.; An, Q.; Bai, J. Z.; Bai, Y.; Bakina, O.; Baldini Ferroli, R.; Ban, Y.; Bennett, D. W.; Bennett, J. V.; Berger, N.; Bertani, M.; Bettoni, D.; Bian, J. M.; Bianchi, F.; Boger, E.; Boyko, I.; Briere, R. A.; Cai, H.; Cai, X.; Cakir, O.; Calcaterra, A.; Cao, G. F.; Cetin, S. A.; Chai, J.; Chang, J. F.; Chelkov, G.; Chen, G.; Chen, H. S.; Chen, J. C.; Chen, M. L.; Chen, S. J.; Chen, X. R.; Chen, Y. B.; Chen, Z. X.; Chu, X. K.; Cibinetto, G.; Dai, H. L.; Dai, J. P.; Dbeyssi, A.; Dedovich, D.; Deng, Z. Y.; Denig, A.; Denysenko, I.; Destefanis, M.; de Mori, F.; Ding, Y.; Dong, C.; Dong, J.; Dong, L. Y.; Dong, M. Y.; Dorjkhaidav, O.; Dou, Z. L.; Du, S. X.; Duan, P. F.; Fang, J.; Fang, S. S.; Fang, X.; Fang, Y.; Farinelli, R.; Fava, L.; Fegan, S.; Feldbauer, F.; Felici, G.; Feng, C. Q.; Fioravanti, E.; Fritsch, M.; Fu, C. D.; Gao, Q.; Gao, X. L.; Gao, Y.; Gao, Y. G.; Gao, Z.; Garillon, B.; Garzia, I.; Goetzen, K.; Gong, L.; Gong, W. X.; Gradl, W.; Greco, M.; Gu, M. H.; Gu, S.; Gu, Y. T.; Guo, A. Q.; Guo, L. B.; Guo, R. P.; Guo, Y. P.; Haddadi, Z.; Han, S.; Hao, X. Q.; Harris, F. A.; He, K. L.; He, X. Q.; Heinsius, F. H.; Held, T.; Heng, Y. K.; Holtmann, T.; Hou, Z. L.; Hu, C.; Hu, H. M.; Hu, J. F.; Hu, T.; Hu, Y.; Huang, G. S.; Huang, J. S.; Huang, S. H.; Huang, X. T.; Huang, X. Z.; Huang, Z. L.; Hussain, T.; Ikegami Andersson, W.; Ji, Q.; Ji, Q. P.; Ji, X. B.; Ji, X. L.; Jiang, X. S.; Jiang, X. Y.; Jiao, J. B.; Jiao, Z.; Jin, D. P.; Jin, S.; Jin, Y.; Johansson, T.; Julin, A.; Kalantar-Nayestanaki, N.; Kang, X. L.; Kang, X. S.; Kavatsyuk, M.; Ke, B. C.; Khan, T.; Khoukaz, A.; Kiese, P.; Kliemt, R.; Koch, L.; Kolcu, O. B.; Kopf, B.; Kornicer, M.; Kuemmel, M.; Kuhlmann, M.; Kupsc, A.; Kühn, W.; Lange, J. S.; Lara, M.; Larin, P.; Lavezzi, L.; Leithoff, H.; Leng, C.; Li, C.; Li, Cheng; Li, D. M.; Li, F.; Li, F. Y.; Li, G.; Li, H. B.; Li, H. J.; Li, J. C.; Li, Jin; Li, K.; Li, K.; Li, K. J.; Li, Lei; Li, P. L.; Li, P. R.; Li, Q. Y.; Li, T.; Li, W. D.; Li, W. G.; Li, X. L.; Li, X. N.; Li, X. Q.; Li, Z. B.; Liang, H.; Liang, Y. F.; Liang, Y. T.; Liao, G. R.; Lin, D. X.; Liu, B.; Liu, B. J.; Liu, C. X.; Liu, D.; Liu, F. H.; Liu, Fang; Liu, Feng; Liu, H. B.; Liu, H. H.; Liu, H. H.; Liu, H. M.; Liu, J. B.; Liu, J. Y.; Liu, K.; Liu, K. Y.; Liu, Ke; Liu, L. D.; Liu, P. L.; Liu, Q.; Liu, S. B.; Liu, X.; Liu, Y. B.; Liu, Z. A.; Liu, Zhiqing; Long, Y. F.; Lou, X. C.; Lu, H. J.; Lu, J. G.; Lu, Y.; Lu, Y. P.; Luo, C. L.; Luo, M. X.; Luo, X. L.; Lyu, X. R.; Ma, F. C.; Ma, H. L.; Ma, L. L.; Ma, M. M.; Ma, Q. M.; Ma, T.; Ma, X. N.; Ma, X. Y.; Ma, Y. M.; Maas, F. E.; Maggiora, M.; Malik, Q. A.; Mao, Y. J.; Mao, Z. P.; Marcello, S.; Meng, Z. X.; Messchendorp, J. G.; Mezzadri, G.; Min, J.; Min, T. J.; Mitchell, R. E.; Mo, X. H.; Mo, Y. J.; Morales Morales, C.; Morello, G.; Muchnoi, N. Yu.; Muramatsu, H.; Mustafa, A.; Nefedov, Y.; Nerling, F.; Nikolaev, I. B.; Ning, Z.; Nisar, S.; Niu, S. L.; Niu, X. Y.; Olsen, S. L.; Ouyang, Q.; Pacetti, S.; Pan, Y.; Papenbrock, M.; Patteri, P.; Pelizaeus, M.; Pellegrino, J.; Peng, H. P.; Peters, K.; Pettersson, J.; Ping, J. L.; Ping, R. G.; Pitka, A.; Poling, R.; Prasad, V.; Qi, H. R.; Qi, M.; Qi, T. Y.; Qian, S.; Qiao, C. F.; Qin, N.; Qin, X. S.; Qin, Z. H.; Qiu, J. F.; Rashid, K. H.; Redmer, C. F.; Richter, M.; Ripka, M.; Rolo, M.; Rong, G.; Rosner, Ch.; Sarantsev, A.; Savrié, M.; Schnier, C.; Schoenning, K.; Shan, W.; Shao, M.; Shen, C. P.; Shen, P. X.; Shen, X. Y.; Sheng, H. Y.; Song, J. J.; Song, W. M.; Song, X. Y.; Sosio, S.; Sowa, C.; Spataro, S.; Sun, G. X.; Sun, J. F.; Sun, L.; Sun, S. S.; Sun, X. H.; Sun, Y. J.; Sun, Y. K.; Sun, Y. Z.; Sun, Z. J.; Sun, Z. T.; Tang, C. J.; Tang, G. Y.; Tang, X.; Tapan, I.; Tiemens, M.; Tsednee, B. T.; Uman, I.; Varner, G. S.; Wang, B.; Wang, B. L.; Wang, B. Q.; Wang, D.; Wang, D. Y.; Wang, Dan; Wang, K.; Wang, L. L.; Wang, L. S.; Wang, M.; Wang, P.; Wang, P. L.; Wang, W. P.; Wang, X. F.; Wang, Y.; Wang, Y. D.; Wang, Y. F.; Wang, Y. Q.; Wang, Z.; Wang, Z. G.; Wang, Z. H.; Wang, Z. Y.; Wang, Zongyuan; Weber, T.; Wei, D. H.; Wei, J. H.; Weidenkaff, P.; Wen, S. P.; Wiedner, U.; Wolke, M.; Wu, L. H.; Wu, L. J.; Wu, Z.; Xia, L.; Xia, Y.; Xiao, D.; Xiao, H.; Xiao, Y. J.; Xiao, Z. J.; Xie, X. H.; Xie, Y. G.; Xie, Y. H.; Xiong, X. A.; Xiu, Q. L.; Xu, G. F.; Xu, J. J.; Xu, L.; Xu, Q. J.; Xu, Q. N.; Xu, X. P.; Yan, L.; Yan, W. B.; Yan, W. C.; Yan, Y. H.; Yang, H. J.; Yang, H. X.; Yang, L.; Yang, Y. H.; Yang, Y. X.; Ye, M.; Ye, M. H.; Yin, J. H.; You, Z. Y.; Yu, B. X.; Yu, C. X.; Yu, J. S.; Yuan, C. Z.; Yuan, Y.; Yuncu, A.; Zafar, A. A.; Zeng, Y.; Zeng, Z.; Zhang, B. X.; Zhang, B. Y.; Zhang, C. C.; Zhang, D. H.; Zhang, H. H.; Zhang, H. Y.; Zhang, J.; Zhang, J. L.; Zhang, J. Q.; Zhang, J. W.; Zhang, J. Y.; Zhang, J. Z.; Zhang, K.; Zhang, L.; Zhang, S. Q.; Zhang, X. Y.; Zhang, Y.; Zhang, Y.; Zhang, Y. H.; Zhang, Y. T.; Zhang, Yu; Zhang, Z. H.; Zhang, Z. P.; Zhang, Z. Y.; Zhao, G.; Zhao, J. W.; Zhao, J. Y.; Zhao, J. Z.; Zhao, Lei; Zhao, Ling; Zhao, M. G.; Zhao, Q.; Zhao, S. J.; Zhao, T. C.; Zhao, Y. B.; Zhao, Z. G.; Zhemchugov, A.; Zheng, B.; Zheng, J. P.; Zheng, W. J.; Zheng, Y. H.; Zhong, B.; Zhou, L.; Zhou, X.; Zhou, X. K.; Zhou, X. R.; Zhou, X. Y.; Zhu, J.; Zhu, K.; Zhu, K. J.; Zhu, S.; Zhu, S. H.; Zhu, X. L.; Zhu, Y. C.; Zhu, Y. S.; Zhu, Z. A.; Zhuang, J.; Zou, B. S.; Zou, J. H.; Besiii Collaboration

    2017-12-01

    Using a sample of 1.31 ×109 J /ψ events collected with the BESIII detector at the BEPCII collider, we study the decays of J /ψ →KSKL and KSKS . The branching fraction of J /ψ →KSKL is determined to be B (J /ψ →KSKL)=(1.93 ±0.01 (stat )±0.05 (syst ))×10-4 , which significantly improves on previous measurements. No clear signal is observed for the J /ψ →KSKS process, and the upper limit at the 95% confidence level for its branching fraction is determined to be B (J /ψ →KSKS)<1.4 ×10-8 , which improves on the previous searches by 2 orders in magnitude and reaches the order of the Einstein-Podolsky-Rosen expectation.

  1. Phenomenological Modeling of Newly Discovered Eclipsing Binary 2MASS J18024395 + 4003309 = VSX J180243.9+400331

    NASA Astrophysics Data System (ADS)

    Andronov, Ivan L.; Kim, Yonggi; Kim, Young-Hee; Yoon, Joh-Na; Chinarova, Lidia L.; Tkachenko, Mariia G.

    2015-06-01

    We present a by-product of our long term photometric monitoring of cataclysmic variables. 2MASS J18024395 +4003309 = VSX J180243.9 +400331 was discovered in the field of the intermediate polar V1323 Her observed using the Korean 1-m telescope located at Mt. Lemmon, USA. An analysis of the two-color VR CCD observations of this variable covers all the phase intervals for the first time. The light curves show this object can be classified as an Algol-type variable with tidally distorted components, and an asymmetry of the maxima (the O'Connell effect). The periodogram analysis confirms the cycle numbering of Andronov et al. (2012) and for the initial approximation, the ephemeris is used as follows: Min I. BJD = 2456074.4904+0.3348837E . For phenomenological modeling, we used the trigonometric polynomial approximation of statistically optimal degree, and a recent method "NAV" ("New Algol Variable") using local specific shapes for the eclipse. Methodological aspects and estimates of the physical parameters based on analysis of phenomenological parameters are presented. As results of our phenomenological model, we obtained for the inclination i=90°, M1=0.745M⊙, M2=0.854M⊙, M=M1+M2=1.599M⊙, the orbital separation a=1.65°109m=2.37R⊙ and relative radii r1=R1/a=0.314 and r2=R2/a=0.360. These estimates may be used as preliminary starting values for further modeling using extended physical models based on the Wilson & Devinney (1971) code and it's extensions

  2. Photolysis rates in correlated overlapping cloud fields: Cloud-J 7.3c

    DOE PAGES

    Prather, M. J.

    2015-08-14

    A new approach for modeling photolysis rates ( J values) in atmospheres with fractional cloud cover has been developed and is implemented as Cloud-J – a multi-scattering eight-stream radiative transfer model for solar radiation based on Fast-J. Using observations of the vertical correlation of cloud layers, Cloud-J 7.3c provides a practical and accurate method for modeling atmospheric chemistry. The combination of the new maximum-correlated cloud groups with the integration over all cloud combinations by four quadrature atmospheres produces mean J values in an atmospheric column with root mean square (rms) errors of 4 % or less compared with 10–20 %more » errors using simpler approximations. Cloud-J is practical for chemistry–climate models, requiring only an average of 2.8 Fast-J calls per atmosphere vs. hundreds of calls with the correlated cloud groups, or 1 call with the simplest cloud approximations. Another improvement in modeling J values, the treatment of volatile organic compounds with pressure-dependent cross sections, is also incorporated into Cloud-J.« less

  3. Intermediate-coupling theory of the spin polaron in the {ital t}-{ital J} model

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Barentzen, H.

    1996-03-01

    The spin polaron in the {ital t-J} model, i.e., a hole dressed by a cloud of virtual magnons of the antiferromagnetic spin background, is treated within the framework of intermediate-coupling theory. The original {ital t}-{ital J} model is first reformulated in terms of spinless fermions and bosons by means of the generalized Dyson-Maleev representation (DMR). The latter may be regarded as the natural extension of the ordinary DMR of pure (undoped) spin systems to the case where holes are present, and is similar to the one originally proposed by Schmitt-Rink, Varma, and Ruckenstein. The reformulated {ital t}-{ital J} model, whichmore » is reminiscent of the Fr{umlt o}hlich Hamiltonian, is then subjected to a series of unitary transformations, analogous to those employed by Lee, Low, and Pines in their treatment of the Fr{umlt o}hlich polaron. Our approach yields an approximate quasiparticle energy {ital E}({ital k}{bold )} as well as the corresponding eigenvector. To explore the range of validity of our theory, the analytic expressions are then further analyzed for intermediate ({ital J}/{ital t}=0.4) and strong ({ital J}/{ital t}=0.08) coupling, where special attention is paid to the quasiparticle bandwidth {ital W}. The intermediate-coupling result for {ital E}({ital k}{bold )} is in excellent agreement with the dispersion curve recently obtained by Dagotto and co-workers by means of a Green function Monte Carlo method. Even in the strong-coupling range the bandshape remains qualitatively correct. The bandwidth {ital W} is rather accurate for weak coupling ({ital J}/{ital t}{approx_gt}3), and still reasonable in the intermediate range 0.4{approx_lt}{ital J}/{ital t}{le}3, where it deviates from the correct values by some 10-20%. Our theory fails, however, to describe the proper behavior of {ital W} in the strong-coupling regime. This shows that the limitations of our approach manifest themselves in the bandwidths rather than in the shapes of the dispersion

  4. Laurence J. Capellas

    ERIC Educational Resources Information Center

    Nishimoto, Warren

    2007-01-01

    Laurence J. Capellas, teacher, principal, and administrator in the Hawai'i Department of Education from 1935 to 1977. Laurence J. Capellas was born in 1913 in Hakalau to two Hawai'i island school-teachers. After attending Hakalau School, St. Mary's School in Hilo, and St. Louis College in Honolulu, he went on to the University of Hawai'i Teachers…

  5. The J-S model versus a non-ideal MHD theory

    NASA Astrophysics Data System (ADS)

    Franchi, Franca; Lazzari, Barbara; Nibbi, Roberta

    2015-07-01

    A new non-ideal electromagnetic interpretation of the J-S type viscoelastic model for polymeric fluids is given and a generalized resisto-elastic magnetohydrodynamic scenario for collisionless plasmas is proposed. The influence of the new theory on the incompressible transverse Alfvén waves is thoroughly investigated.

  6. Optical spectroscopy of SN2014J

    NASA Astrophysics Data System (ADS)

    Kotak, R.

    2014-01-01

    Authors: J. Polshaw, R. Kotak, J. R. Maund, S. J. Smartt (QUB), M. Fraser, N. Walton (IoA), J. M. Abreu (IAC), M. Balcells, C. Benn, J. Mendez, A. Oscoz, O. Zamora, C. Zurita (ING) A spectrum of the supernova SN 2014J in the nearby galaxy M82 was obtained on Jan. 23.2 2014 (UT) at the 2.54m Isaac Newton Telescope (INT) with IDS and the grating R1200R (approximate wavelength range 5600 - 7500A, at 2A resolution).

  7. Dalitz plot analyses of J /ψ →π+π-π0, J /ψ →K+K-π0, and J /ψ →Ks0K±π∓ produced via e+e- annihilation with initial-state radiation

    NASA Astrophysics Data System (ADS)

    Lees, J. P.; Poireau, V.; Tisserand, V.; Grauges, E.; Palano, A.; Eigen, G.; Brown, D. N.; Kolomensky, Yu. G.; Fritsch, M.; Koch, H.; Schroeder, T.; Hearty, C.; Mattison, T. S.; McKenna, J. A.; So, R. Y.; Blinov, V. E.; Buzykaev, A. R.; Druzhinin, V. P.; Golubev, V. B.; Kravchenko, E. A.; Onuchin, A. P.; Serednyakov, S. I.; Skovpen, Yu. I.; Solodov, E. P.; Todyshev, K. Yu.; Lankford, A. J.; Gary, J. W.; Long, O.; Eisner, A. M.; Lockman, W. S.; Panduro Vazquez, W.; Chao, D. S.; Cheng, C. H.; Echenard, B.; Flood, K. T.; Hitlin, D. G.; Kim, J.; Miyashita, T. S.; Ongmongkolkul, P.; Porter, F. C.; Röhrken, M.; Huard, Z.; Meadows, B. T.; Pushpawela, B. G.; Sokoloff, M. D.; Sun, L.; Smith, J. G.; Wagner, S. R.; Bernard, D.; Verderi, M.; Bettoni, D.; Bozzi, C.; Calabrese, R.; Cibinetto, G.; Fioravanti, E.; Garzia, I.; Luppi, E.; Santoro, V.; Calcaterra, A.; de Sangro, R.; Finocchiaro, G.; Martellotti, S.; Patteri, P.; Peruzzi, I. M.; Piccolo, M.; Rotondo, M.; Zallo, A.; Passaggio, S.; Patrignani, C.; Lacker, H. M.; Bhuyan, B.; Szczepaniak, A. P.; Mallik, U.; Chen, C.; Cochran, J.; Prell, S.; Ahmed, H.; Pennington, M. R.; Gritsan, A. V.; Arnaud, N.; Davier, M.; Le Diberder, F.; Lutz, A. M.; Wormser, G.; Lange, D. J.; Wright, D. M.; Coleman, J. P.; Gabathuler, E.; Hutchcroft, D. E.; Payne, D. J.; Touramanis, C.; Bevan, A. J.; Di Lodovico, F.; Sacco, R.; Cowan, G.; Banerjee, Sw.; Brown, D. N.; Davis, C. L.; Denig, A. G.; Gradl, W.; Griessinger, K.; Hafner, A.; Schubert, K. R.; Barlow, R. J.; Lafferty, G. D.; Cenci, R.; Jawahery, A.; Roberts, D. A.; Cowan, R.; Robertson, S. H.; Dey, B.; Neri, N.; Palombo, F.; Cheaib, R.; Cremaldi, L.; Godang, R.; Summers, D. J.; Taras, P.; De Nardo, G.; Sciacca, C.; Raven, G.; Jessop, C. P.; LoSecco, J. M.; Honscheid, K.; Kass, R.; Gaz, A.; Margoni, M.; Posocco, M.; Simi, G.; Simonetto, F.; Stroili, R.; Akar, S.; Ben-Haim, E.; Bomben, M.; Bonneaud, G. R.; Calderini, G.; Chauveau, J.; Marchiori, G.; Ocariz, J.; Biasini, M.; Manoni, E.; Rossi, A.; Batignani, G.; Bettarini, S.; Carpinelli, M.; Casarosa, G.; Chrzaszcz, M.; Forti, F.; Giorgi, M. A.; Lusiani, A.; Oberhof, B.; Paoloni, E.; Rama, M.; Rizzo, G.; Walsh, J. J.; Smith, A. J. S.; Anulli, F.; Faccini, R.; Ferrarotto, F.; Ferroni, F.; Pilloni, A.; Piredda, G.; Bünger, C.; Dittrich, S.; Grünberg, O.; Heß, M.; Leddig, T.; Voß, C.; Waldi, R.; Adye, T.; Wilson, F. F.; Emery, S.; Vasseur, G.; Aston, D.; Cartaro, C.; Convery, M. R.; Dorfan, J.; Dunwoodie, W.; Ebert, M.; Field, R. C.; Fulsom, B. G.; Graham, M. T.; Hast, C.; Innes, W. R.; Kim, P.; Leith, D. W. G. S.; Luitz, S.; MacFarlane, D. B.; Muller, D. R.; Neal, H.; Ratcliff, B. N.; Roodman, A.; Sullivan, M. K.; Va'vra, J.; Wisniewski, W. J.; Purohit, M. V.; Wilson, J. R.; Randle-Conde, A.; Sekula, S. J.; Bellis, M.; Burchat, P. R.; Puccio, E. M. T.; Alam, M. S.; Ernst, J. A.; Gorodeisky, R.; Guttman, N.; Peimer, D. R.; Soffer, A.; Spanier, S. M.; Ritchie, J. L.; Schwitters, R. F.; Izen, J. M.; Lou, X. C.; Bianchi, F.; De Mori, F.; Filippi, A.; Gamba, D.; Lanceri, L.; Vitale, L.; Martinez-Vidal, F.; Oyanguren, A.; Albert, J.; Beaulieu, A.; Bernlochner, F. U.; King, G. J.; Kowalewski, R.; Lueck, T.; Nugent, I. M.; Roney, J. M.; Sobie, R. J.; Tasneem, N.; Gershon, T. J.; Harrison, P. F.; Latham, T. E.; Prepost, R.; Wu, S. L.; BaBar Collaboration

    2017-04-01

    We study the processes e+e- →γISRJ /ψ , where J /ψ →π+π-π0, J /ψ →K+K-π0, and J /ψ →KS0K±π∓ using a data sample of 519 fb-1 recorded with the BABAR detector operating at the SLAC PEP-II asymmetric-energy e+e- collider at center-of-mass energies at and near the Υ (n S ) (n =2 ,3 ,4 ) resonances. We measure the ratio of branching fractions R1=B/(J /ψ →K+K-π0) B (J /ψ →π+π-π0) and R2=B/(J /ψ →KS0K±π∓) B (J /ψ →π+π-π0) . We perform Dalitz plot analyses of the three J /ψ decay modes and measure fractions for resonances contributing to the decays. We also analyze the J /ψ →π+π-π0 decay using the Veneziano model. We observe structures compatible with the presence of ρ (1450 ) in all three J /ψ decay modes and measure the relative branching fraction: R (ρ (1450 ))=B/(ρ (1450 )→K+K-) B (ρ (1450 )→π+π-) =0.307 ±0.084 (stat)±0.082 (sys).

  8. Genetic dissection of intermale aggressive behavior in BALB/cJ and A/J mice.

    PubMed

    Dow, H C; Kreibich, A S; Kaercher, K A; Sankoorikal, G M V; Pauley, E D; Lohoff, F W; Ferraro, T N; Li, H; Brodkin, E S

    2011-02-01

    Aggressive behaviors are disabling, treatment refractory, and sometimes lethal symptoms of several neuropsychiatric disorders. However, currently available treatments for patients are inadequate, and the underlying genetics and neurobiology of aggression is only beginning to be elucidated. Inbred mouse strains are useful for identifying genomic regions, and ultimately the relevant gene variants (alleles) in these regions, that affect mammalian aggressive behaviors, which, in turn, may help to identify neurobiological pathways that mediate aggression. The BALB/cJ inbred mouse strain exhibits relatively high levels of intermale aggressive behaviors and shows multiple brain and behavioral phenotypes relevant to neuropsychiatric syndromes associated with aggression. The A/J strain shows very low levels of aggression. We hypothesized that a cross between BALB/cJ and A/J inbred strains would reveal genomic loci that influence the tendency to initiate intermale aggressive behavior. To identify such loci, we conducted a genomewide scan in an F2 population of 660 male mice bred from BALB/cJ and A/J inbred mouse strains. Three significant loci on chromosomes 5, 10 and 15 that influence aggression were identified. The chromosome 5 and 15 loci are completely novel, and the chromosome 10 locus overlaps an aggression locus mapped in our previous study that used NZB/B1NJ and A/J as progenitor strains. Haplotype analysis of BALB/cJ, NZB/B1NJ and A/J strains showed three positional candidate genes in the chromosome 10 locus. Future studies involving fine genetic mapping of these loci as well as additional candidate gene analysis may lead to an improved biological understanding of mammalian aggressive behaviors. © 2010 The Authors. Genes, Brain and Behavior © 2010 Blackwell Publishing Ltd and International Behavioural and Neural Genetics Society.

  9. Near-threshold J/ψ-meson photoproduction on nuclei

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Paryev, E. Ya.; Kiselev, Yu. T., E-mail: yurikis@itep.ru

    On the basis of the first-collision model that relies on the nuclear spectral function and which includes incoherent processes involving charmonium production in proton–nucleon collisions, the photoproduction of J/ψ mesons on nuclei is considered at energies close to the threshold for their production on a nucleon. The absorption of final J/ψ mesons, their formation length, and the binding and Fermi motion of target nucleons are taken into account in this model along with the effect of the nuclear potential on these processes. The A dependences of the absolute and relative charmonium yields are calculated together with absolute and relative excitationmore » functions under various assumptions on the magnitude of the cross section for J/ψN absorption, the J/ψ-meson formation length, and their inmedium modification. It is shown that, at energies above the threshold, these features are virtually independent of the formation length and the change in the J/ψ-meson mass in nuclear matter but are rather highly sensitive to the cross section for J/ψN interaction. The calculations performed in the present study can be used to determine the unknown cross section for J/ψ-meson absorption in nuclei from a comparison of their results with data expected from experiments in the Hall C of the CEBAF (USA) facility upgraded to the energy of 12 GeV. It is also shown that the absolute and relative excitation functions for J/ψ mesons in photon–nucleus reactions at subthreshold energies are sensitive to the change in the meson mass and, hence, carry information about the properties of charmonium in nuclear matter.« less

  10. J85 Rejuvenation Through Technology Insertion

    DTIC Science & Technology

    2000-10-01

    and Sabre 75 business addition to military production, the J85 was jets . Number Model Produced Aircraft Type(s) Engine Type Thrust (lbs) J85-GE-4 740...REJUVENATION THROUGH TECHNOLOGY INSERTION T.A. Brisken, P.N. Howell, A.C. Ewing Military Engines Operation GE Aircraft Engines 1 Neumann Way Cincinnati...OH 45215, USA Summary thrust to weight ratio turbojet engines with potential application to early cruise missiles and drones. The history of the

  11. 7. Detail view of 1866 cornerstone (J.J. Havis and M.F. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Detail view of 1866 cornerstone (J.J. Havis and M.F. Echols, Builders). This cornerstone was moved to the third floor, west elevation of an addition built in 1899. - Riverdale Cotton Mill, Corner of Middle & Lower Streets, Valley, Chambers County, AL

  12. Exploring entropic uncertainty relation in the Heisenberg XX model with inhomogeneous magnetic field

    NASA Astrophysics Data System (ADS)

    Huang, Ai-Jun; Wang, Dong; Wang, Jia-Ming; Shi, Jia-Dong; Sun, Wen-Yang; Ye, Liu

    2017-08-01

    In this work, we investigate the quantum-memory-assisted entropic uncertainty relation in a two-qubit Heisenberg XX model with inhomogeneous magnetic field. It has been found that larger coupling strength J between the two spin-chain qubits can effectively reduce the entropic uncertainty. Besides, we observe the mechanics of how the inhomogeneous field influences the uncertainty, and find out that when the inhomogeneous field parameter b<1, the uncertainty will decrease with the decrease of the inhomogeneous field parameter b, conversely, the uncertainty will increase with decreasing b under the condition that b>1. Intriguingly, the entropic uncertainty can shrink to zero when the coupling coefficients are relatively large, while the entropic uncertainty only reduces to 1 with the increase of the homogeneous magnetic field. Additionally, we observe the purity of the state and Bell non-locality and obtain that the entropic uncertainty is anticorrelated with both the purity and Bell non-locality of the evolution state.

  13. STS-51J Mission Insignia

    NASA Technical Reports Server (NTRS)

    1985-01-01

    The 51-J mission insignia, designed by Atlantis's first crew, pays tribute to the Statue of Liberty and the ideas it symbolizes. The historical gateway figure bears additional significance for Astronauts Karol J. Bobko, mission commander; and Ronald J. Grabe, pilot, both New Your Natives.

  14. Repetitive behavior profile and supersensitivity to amphetamine in the C58/J mouse model of autism.

    PubMed

    Moy, Sheryl S; Riddick, Natallia V; Nikolova, Viktoriya D; Teng, Brian L; Agster, Kara L; Nonneman, Randal J; Young, Nancy B; Baker, Lorinda K; Nadler, Jessica J; Bodfish, James W

    2014-02-01

    Restricted repetitive behaviors are core symptoms of autism spectrum disorders (ASDs). The range of symptoms encompassed by the repetitive behavior domain includes lower-order stereotypy and self-injury, and higher-order indices of circumscribed interests and cognitive rigidity. Heterogeneity in clinical ASD profiles suggests that specific manifestations of repetitive behavior reflect differential neuropathology. The present studies utilized a set of phenotyping tasks to determine a repetitive behavior profile for the C58/J mouse strain, a model of ASD core symptoms. In an observational screen, C58/J demonstrated overt motor stereotypy, but not over-grooming, a commonly-used measure for mouse repetitive behavior. Amphetamine did not exacerbate motor stereotypy, but had enhanced stimulant effects on locomotion and rearing in C58/J, compared to C57BL/6J. Both C58/J and Grin1 knockdown mice, another model of ASD-like behavior, had marked deficits in marble-burying. In a nose poke task for higher-order repetitive behavior, C58/J had reduced holeboard exploration and preference for non-social, versus social, olfactory stimuli, but did not demonstrate cognitive rigidity following familiarization to an appetitive stimulus. Analysis of available high-density genotype data indicated specific regions of divergence between C58/J and two highly-sociable strains with common genetic lineage. Strain genome comparisons identified autism candidate genes, including Cntnap2 and Slc6a4, located within regions divergent in C58/J. However, Grin1, Nlgn1, Sapap3, and Slitrk5, genes linked to repetitive over-grooming, were not in regions of divergence. These studies suggest that specific repetitive phenotypes can be used to distinguish ASD mouse models, with implications for divergent underlying mechanisms for different repetitive behavior profiles. Copyright © 2013 Elsevier B.V. All rights reserved.

  15. 30 CFR Appendix A to Subpart J of... - Appendix A to Subpart J of Part 75

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Appendix A to Subpart J of Part 75 A Appendix A to Subpart J of Part 75 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR... Medium-Voltage Alternating Current Circuits Pt. 75, Subpt. J, App. A Appendix A to Subpart J of Part 75...

  16. Noise Strength Estimates of Three SGRs: Swift J1822.3-1606, SGR J1833-0832 and Swift J1834.9-0846

    NASA Astrophysics Data System (ADS)

    Serim, M. M.; Inam, S. Ç.; Baykal, A.

    2012-12-01

    We studied timing solutions of the three magnetars SWIFT J1822.3-1606, SGR J1833-0832 and Swift J1834.9-0846. We extracted the residuals of pulse arrival times with respect to the constant pulse frequency derivative. Using polynomial estimator techniques, we estimated the noise strengths of the sources. Our results showed that the noise strength and spin-down rate are strongly correlated, indicating that increase in spin-down rate leads to more torque noise on the magnetars. We are in progress of extending our analysis to the other magnetars.

  17. Strain and sex differences in anxiety-like and social behaviors in C57BL/6J and BALB/cJ mice.

    PubMed

    An, Xiao-Lei; Zou, Jun-Xian; Wu, Rui-Yong; Yang, Ying; Tai, Fa-Dao; Zeng, Shuang-Yan; Jia, Rui; Zhang, Xia; Liu, En-Qi; Broders, Hugh

    2011-01-01

    Mood disorders are more frequent in women than men, however, the majority of research has focused on male rodents as animal models. We used a variety of common behavioral tests to look for differences in anxiety-like and social behaviors between and within C57BL/6J and BALB/cJ mice. Our results show that female C57BL/6J mice exhibited lower levels of anxiety-like behavior and higher levels of activity than female BALB/cJ during the open field and elevated plus maze tests. Principal component analysis generated more factors in the behavioral variables of males than females. In the open field, a sex difference was also found and factor 1 emerged as anxiety in males, and motor activity in females. While C57BL/6J mice were found to have higher levels of social exploration and social contacts, differences were found between the sexes (females were more social) in both strains for this measure and also for anxiety-like behaviors. When interacting with animals of the same sex, levels of sniffing body and huddling in both male and female C57BL/6J mice were higher than those in male and female BALB/cJ mice. However, in the between-sex interactions, male C57BL/6J mice sniffed the stimulus mouse less, and female C57BL/6J mice sniffed the stimulus more compared to BALB/cJ mice. This study provides important behavioral phenotypes and confirms the multidimensional behavioral structure of two widely used mice strains.

  18. The J3 SCR model applied to resonant converter simulation

    NASA Technical Reports Server (NTRS)

    Avant, R. L.; Lee, F. C. Y.

    1985-01-01

    The J3 SCR model is a continuous topology computer model for the SCR. Its circuit analog and parameter estimation procedure are uniformly applicable to popular computer-aided design and analysis programs such as SPICE2 and SCEPTRE. The circuit analog is based on the intrinsic three pn junction structure of the SCR. The parameter estimation procedure requires only manufacturer's specification sheet quantities as a data base.

  19. Bound on the Ratio of Decay Amplitudes for B¯0→J/ψK*0 and B0→J/ψK*0

    NASA Astrophysics Data System (ADS)

    Aubert, B.; Barate, R.; Boutigny, D.; Couderc, F.; Gaillard, J.-M.; Hicheur, A.; Karyotakis, Y.; Lees, J. P.; Tisserand, V.; Zghiche, A.; Palano, A.; Pompili, A.; Chen, J. C.; Qi, N. D.; Rong, G.; Wang, P.; Zhu, Y. S.; Eigen, G.; Ofte, I.; Stugu, B.; Abrams, G. S.; Borgland, A. W.; Breon, A. B.; Brown, D. N.; Button-Shafer, J.; Cahn, R. N.; Charles, E.; Day, C. T.; Gill, M. S.; Gritsan, A. V.; Groysman, Y.; Jacobsen, R. G.; Kadel, R. W.; Kadyk, J.; Kerth, L. T.; Kolomensky, Yu. G.; Kukartsev, G.; Lynch, G.; Mir, L. M.; Oddone, P. J.; Orimoto, T. J.; Pripstein, M.; Roe, N. A.; Ronan, M. T.; Shelkov, V. G.; Wenzel, W. A.; Ford, K. E.; Harrison, T. J.; Hawkes, C. M.; Morgan, S. E.; Watson, A. T.; Fritsch, M.; Goetzen, K.; Held, T.; Koch, H.; Lewandowski, B.; Pelizaeus, M.; Steinke, M.; Boyd, J. T.; Chevalier, N.; Cottingham, W. N.; Kelly, M. P.; Latham, T. E.; Wilson, F. F.; Cuhadar-Donszelmann, T.; Hearty, C.; Knecht, N. S.; Mattison, T. S.; McKenna, J. A.; Thiessen, D.; Khan, A.; Kyberd, P.; Teodorescu, L.; Blinov, V. E.; Bukin, A. D.; Druzhinin, V. P.; Golubev, V. B.; Ivanchenko, V. N.; Kravchenko, E. A.; Onuchin, A. P.; Serednyakov, S. I.; Skovpen, Yu. I.; Solodov, E. P.; Yushkov, A. N.; Best, D.; Bruinsma, M.; Chao, M.; Eschrich, I.; Kirkby, D.; Lankford, A. J.; Mandelkern, M.; Mommsen, R. K.; Roethel, W.; Stoker, D. P.; Buchanan, C.; Hartfiel, B. L.; Gary, J. W.; Shen, B. C.; Wang, K.; del Re, D.; Hadavand, H. K.; Hill, E. J.; Macfarlane, D. B.; Paar, H. P.; Rahatlou, Sh.; Sharma, V.; Berryhill, J. W.; Campagnari, C.; Dahmes, B.; Levy, S. L.; Long, O.; Lu, A.; Mazur, M. A.; Richman, J. D.; Verkerke, W.; Beck, T. W.; Eisner, A. M.; Heusch, C. A.; Lockman, W. S.; Schalk, T.; Schmitz, R. E.; Schumm, B. A.; Seiden, A.; Spradlin, P.; Williams, D. C.; Wilson, M. G.; Albert, J.; Chen, E.; Dubois-Felsmann, G. P.; Dvoretskii, A.; Hitlin, D. G.; Narsky, I.; Piatenko, T.; Porter, F. C.; Ryd, A.; Samuel, A.; Yang, S.; Jayatilleke, S.; Mancinelli, G.; Meadows, B. T.; Sokoloff, M. D.; Abe, T.; Blanc, F.; Bloom, P.; Chen, S.; Ford, W. T.; Nauenberg, U.; Olivas, A.; Rankin, P.; Smith, J. G.; Zhang, J.; Zhang, L.; Chen, A.; Harton, J. L.; Soffer, A.; Toki, W. H.; Wilson, R. J.; Zeng, Q. L.; Altenburg, D.; Brandt, T.; Brose, J.; Colberg, T.; Dickopp, M.; Feltresi, E.; Hauke, A.; Lacker, H. M.; Maly, E.; Müller-Pfefferkorn, R.; Nogowski, R.; Otto, S.; Petzold, A.; Schubert, J.; Schubert, K. R.; Schwierz, R.; Spaan, B.; Sundermann, J. E.; Bernard, D.; Bonneaud, G. R.; Brochard, F.; Grenier, P.; Schrenk, S.; Thiebaux, Ch.; Vasileiadis, G.; Verderi, M.; Bard, D. J.; Clark, P. J.; Lavin, D.; Muheim, F.; Playfer, S.; Xie, Y.; Andreotti, M.; Azzolini, V.; Bettoni, D.; Bozzi, C.; Calabrese, R.; Cibinetto, G.; Luppi, E.; Negrini, M.; Piemontese, L.; Sarti, A.; Treadwell, E.; Baldini-Ferroli, R.; Calcaterra, A.; de Sangro, R.; Finocchiaro, G.; Patteri, P.; Piccolo, M.; Zallo, A.; Buzzo, A.; Capra, R.; Contri, R.; Crosetti, G.; Lo Vetere, M.; Macri, M.; Monge, M. R.; Passaggio, S.; Patrignani, C.; Robutti, E.; Santroni, A.; Tosi, S.; Bailey, S.; Brandenburg, G.; Morii, M.; Won, E.; Dubitzky, R. S.; Langenegger, U.; Bhimji, W.; Bowerman, D. A.; Dauncey, P. D.; Egede, U.; Gaillard, J. R.; Morton, G. W.; Nash, J. A.; Taylor, G. P.; Charles, M. J.; Grenier, G. J.; Mallik, U.; Cochran, J.; Crawley, H. B.; Lamsa, J.; Meyer, W. T.; Prell, S.; Rosenberg, E. I.; Yi, J.; Davier, M.; Grosdidier, G.; Höcker, A.; Laplace, S.; Le Diberder, F.; Lepeltier, V.; Lutz, A. M.; Petersen, T. C.; Plaszczynski, S.; Schune, M. H.; Tantot, L.; Wormser, G.; Cheng, C. H.; Lange, D. J.; Simani, M. C.; Wright, D. M.; Bevan, A. J.; Coleman, J. P.; Fry, J. R.; Gabathuler, E.; Gamet, R.; Parry, R. J.; Payne, D. J.; Sloane, R. J.; Touramanis, C.; Back, J. J.; Cormack, C. M.; Harrison, P. F.; Mohanty, G. B.; Brown, C. L.; Cowan, G.; Flack, R. L.; Flaecher, H. U.; Green, M. G.; Marker, C. E.; McMahon, T. R.; Ricciardi, S.; Salvatore, F.; Vaitsas, G.; Winter, M. A.; Brown, D.; Davis, C. L.; Allison, J.; Barlow, N. R.; Barlow, R. J.; Hart, P. A.; Hodgkinson, M. C.; Lafferty, G. D.; Lyon, A. J.; Williams, J. C.; Farbin, A.; Hulsbergen, W. D.; Jawahery, A.; Kovalskyi, D.; Lae, C. K.; Lillard, V.; Roberts, D. A.; Blaylock, G.; Dallapiccola, C.; Flood, K. T.; Hertzbach, S. S.; Kofler, R.; Koptchev, V. B.; Moore, T. B.; Saremi, S.; Staengle, H.; Willocq, S.; Cowan, R.; Sciolla, G.; Taylor, F.; Yamamoto, R. K.; Mangeol, D. J.; Patel, P. M.; Robertson, S. H.; Lazzaro, A.; Palombo, F.; Bauer, J. M.; Cremaldi, L.; Eschenburg, V.; Godang, R.; Kroeger, R.; Reidy, J.; Sanders, D. A.; Summers, D. J.; Zhao, H. W.; Brunet, S.; Côté, D.; Taras, P.; Nicholson, H.; Cavallo, N.; Fabozzi, F.; Gatto, C.; Lista, L.; Monorchio, D.; Paolucci, P.; Piccolo, D.; Sciacca, C.; Baak, M.; Bulten, H.; Raven, G.; Wilden, L.; Jessop, C. P.; Losecco, J. M.; Gabriel, T. A.; Allmendinger, T.; Brau, B.; Gan, K. K.; Honscheid, K.; Hufnagel, D.; Kagan, H.; Kass, R.; Pulliam, T.; Rahimi, A. M.; Ter-Antonyan, R.; Wong, Q. K.; Brau, J.; Frey, R.; Igonkina, O.; Potter, C. T.; Sinev, N. B.; Strom, D.; Torrence, E.; Colecchia, F.; Dorigo, A.; Galeazzi, F.; Margoni, M.; Morandin, M.; Posocco, M.; Rotondo, M.; Simonetto, F.; Stroili, R.; Tiozzo, G.; Voci, C.; Benayoun, M.; Briand, H.; Chauveau, J.; David, P.; de La Vaissière, Ch.; del Buono, L.; Hamon, O.; John, M. J.; Leruste, Ph.; Malcles, J.; Ocariz, J.; Pivk, M.; Roos, L.; T'jampens, S.; Therin, G.; Manfredi, P. F.; Re, V.; Behera, P. K.; Gladney, L.; Guo, Q. H.; Panetta, J.; Anulli, F.; Biasini, M.; Peruzzi, I. M.; Pioppi, M.; Angelini, C.; Batignani, G.; Bettarini, S.; Bondioli, M.; Bucci, F.; Calderini, G.; Carpinelli, M.; del Gamba, V.; Forti, F.; Giorgi, M. A.; Lusiani, A.; Marchiori, G.; Martinez-Vidal, F.; Morganti, M.; Neri, N.; Paoloni, E.; Rama, M.; Rizzo, G.; Sandrelli, F.; Walsh, J.; Haire, M.; Judd, D.; Paick, K.; Wagoner, D. E.; Danielson, N.; Elmer, P.; Lau, Y. P.; Lu, C.; Miftakov, V.; Olsen, J.; Smith, A. J.; Telnov, A. V.; Bellini, F.; Cavoto, G.; Faccini, R.; Ferrarotto, F.; Ferroni, F.; Gaspero, M.; Li Gioi, L.; Mazzoni, M. A.; Morganti, S.; Pierini, M.; Piredda, G.; Tehrani, F. Safai; Voena, C.; Christ, S.; Wagner, G.; Waldi, R.; Adye, T.; de Groot, N.; Franek, B.; Geddes, N. I.; Gopal, G. P.; Olaiya, E. O.; Aleksan, R.; Emery, S.; Gaidot, A.; Ganzhur, S. F.; Giraud, P.-F.; Hamel de Monchenault, G.; Kozanecki, W.; Langer, M.; Legendre, M.; London, G. W.; Mayer, B.; Schott, G.; Vasseur, G.; Yèche, Ch.; Zito, M.; Purohit, M. V.; Weidemann, A. W.; Wilson, J. R.; Yumiceva, F. X.; Aston, D.; Bartoldus, R.; Berger, N.; Boyarski, A. M.; Buchmueller, O. L.; Convery, M. R.; Cristinziani, M.; de Nardo, G.; Dong, D.; Dorfan, J.; Dujmic, D.; Dunwoodie, W.; Elsen, E. E.; Fan, S.; Field, R. C.; Glanzman, T.; Gowdy, S. J.; Hadig, T.; Halyo, V.; Hast, C.; Hryn'ova, T.; Innes, W. R.; Kelsey, M. H.; Kim, P.; Kocian, M. L.; Leith, D. W.; Libby, J.; Luitz, S.; Luth, V.; Lynch, H. L.; Marsiske, H.; Messner, R.; Muller, D. R.; O'Grady, C. P.; Ozcan, V. E.; Perazzo, A.; Perl, M.; Petrak, S.; Ratcliff, B. N.; Roodman, A.; Salnikov, A. A.; Schindler, R. H.; Schwiening, J.; Simi, G.; Snyder, A.; Soha, A.; Stelzer, J.; Su, D.; Sullivan, M. K.; Va'Vra, J.; Wagner, S. R.; Weaver, M.; Weinstein, A. J.; Wisniewski, W. J.; Wittgen, M.; Wright, D. H.; Yarritu, A. K.; Young, C. C.; Burchat, P. R.; Edwards, A. J.; Meyer, T. I.; Petersen, B. A.; Roat, C.; Ahmed, S.; Alam, M. S.; Ernst, J. A.; Saeed, M. A.; Saleem, M.; Wappler, F. R.; Bugg, W.; Krishnamurthy, M.; Spanier, S. M.; Eckmann, R.; Kim, H.; Ritchie, J. L.; Satpathy, A.; Schwitters, R. F.; Izen, J. M.; Kitayama, I.; Lou, X. C.; Ye, S.; Bianchi, F.; Bona, M.; Gallo, F.; Gamba, D.; Borean, C.; Bosisio, L.; Cartaro, C.; Cossutti, F.; della Ricca, G.; Dittongo, S.; Grancagnolo, S.; Lanceri, L.; Poropat, P.; Vitale, L.; Vuagnin, G.; Panvini, R. S.; Banerjee, Sw.; Brown, C. M.; Fortin, D.; Jackson, P. D.; Kowalewski, R.; Roney, J. M.; Band, H. R.; Dasu, S.; Datta, M.; Eichenbaum, A. M.; Graham, M.; Hollar, J. J.; Johnson, J. R.; Kutter, P. E.; Li, H.; Liu, R.; Lodovico, F. Di; Mihalyi, A.; Mohapatra, A. K.; Pan, Y.; Prepost, R.; Rubin, A. E.; Sekula, S. J.; Tan, P.; von Wimmersperg-Toeller, J. H.; Wu, J.; Wu, S. L.; Yu, Z.; Greene, M. G.; Neal, H.

    2004-08-01

    We have measured the time-dependent decay rate for the process B→J/ψK*0(892) in a sample of about 88×106 Υ(4S)→BB¯ decays collected with the BABAR detector at the PEP-II asymmetric-energy B factory at SLAC. In this sample we study flavor-tagged events in which one neutral B meson is reconstructed in the J/ψK*0 or J/ψK¯*0 final state. We measure the coefficients of the cosine and sine terms in the time-dependent asymmetries for J/ψK*0 and J/ψK¯*0, find them to be consistent with the standard model expectations, and set upper limits at 90% confidence level (C.L.) on the decay amplitude ratios |A(B¯0→J/ψK*0)|/|A(B0→J/ψK*0)|<0.26 and |A(B0→J/ψK¯*0)|/|A(B¯0→J/ψK¯*0)|<0.32. For a single ratio of wrong-flavor to favored amplitudes for B0 and B¯0 combined, we obtain an upper limit of 0.25 at 90% C.L.

  20. jà vu experiences are rarely associated with pathological dissociation.

    PubMed

    Adachi, Naoto; Akanuma, Nozomi; Akanu, Nozomi; Adachi, Takuya; Takekawa, Yoshikazu; Adachi, Yasushi; Ito, Masumi; Ikeda, Hiroshi

    2008-05-01

    We investigated the relation between déjà vu and dissociative experiences in nonclinical subjects. In 227 adult volunteers, déjà vu and dissociative experiences were evaluated by means of the inventory of déjà vu experiences assessment and dissociative experiences scale (DES). Déjà vu experiences occurred in 162 (71.4%) individuals. In univariate correlation analysis, the frequency of déjà vu experiences, as well as 5 other inventory of déjà vu experiences assessment symptoms and age at the time of evaluation, correlated significantly with the DES score. After exclusion of intercorrelative effects using multiple regression analysis, déjà vu experiences did not remain in the model. The DES score was best correlated with a model that included age, jamais vu, depersonalization, and precognitive dreams. Two indices for pathological dissociation (DES-taxon and DES > or = 30) were not associated with déjà vu experiences. Our findings suggest that déjà vu experiences are unlikely to be core pathological dissociative experiences.

  1. Comprehensive Aspectual UML approach to support AspectJ.

    PubMed

    Magableh, Aws; Shukur, Zarina; Ali, Noorazean Mohd

    2014-01-01

    Unified Modeling Language is the most popular and widely used Object-Oriented modelling language in the IT industry. This study focuses on investigating the ability to expand UML to some extent to model crosscutting concerns (Aspects) to support AspectJ. Through a comprehensive literature review, we identify and extensively examine all the available Aspect-Oriented UML modelling approaches and find that the existing Aspect-Oriented Design Modelling approaches using UML cannot be considered to provide a framework for a comprehensive Aspectual UML modelling approach and also that there is a lack of adequate Aspect-Oriented tool support. This study also proposes a set of Aspectual UML semantic rules and attempts to generate AspectJ pseudocode from UML diagrams. The proposed Aspectual UML modelling approach is formally evaluated using a focus group to test six hypotheses regarding performance; a "good design" criteria-based evaluation to assess the quality of the design; and an AspectJ-based evaluation as a reference measurement-based evaluation. The results of the focus group evaluation confirm all the hypotheses put forward regarding the proposed approach. The proposed approach provides a comprehensive set of Aspectual UML structural and behavioral diagrams, which are designed and implemented based on a comprehensive and detailed set of AspectJ programming constructs.

  2. Comprehensive Aspectual UML Approach to Support AspectJ

    PubMed Central

    Magableh, Aws; Shukur, Zarina; Mohd. Ali, Noorazean

    2014-01-01

    Unified Modeling Language is the most popular and widely used Object-Oriented modelling language in the IT industry. This study focuses on investigating the ability to expand UML to some extent to model crosscutting concerns (Aspects) to support AspectJ. Through a comprehensive literature review, we identify and extensively examine all the available Aspect-Oriented UML modelling approaches and find that the existing Aspect-Oriented Design Modelling approaches using UML cannot be considered to provide a framework for a comprehensive Aspectual UML modelling approach and also that there is a lack of adequate Aspect-Oriented tool support. This study also proposes a set of Aspectual UML semantic rules and attempts to generate AspectJ pseudocode from UML diagrams. The proposed Aspectual UML modelling approach is formally evaluated using a focus group to test six hypotheses regarding performance; a “good design” criteria-based evaluation to assess the quality of the design; and an AspectJ-based evaluation as a reference measurement-based evaluation. The results of the focus group evaluation confirm all the hypotheses put forward regarding the proposed approach. The proposed approach provides a comprehensive set of Aspectual UML structural and behavioral diagrams, which are designed and implemented based on a comprehensive and detailed set of AspectJ programming constructs. PMID:25136656

  3. Explaining a CMS e e j j excess with R -parity violating supersymmetry and implications for neutrinoless double beta decay

    NASA Astrophysics Data System (ADS)

    Allanach, Ben; Biswas, Sanjoy; Mondal, Subhadeep; Mitra, Manimala

    2015-01-01

    A recent CMS search for the right-handed gauge boson WR reports an interesting deviation from the Standard Model. The search has been conducted in the e e j j channel and has shown a 2.8 σ excess around me e j j˜2 TeV . In this work, we explain the reported CMS excess with R -parity violating supersymmetry. We consider resonant selectron and sneutrino production, followed by the three body decays of the neutralino and chargino via an R -parity violating coupling. We fit the excess for slepton masses around 2 TeV. The scenario can further be tested in neutrinoless double beta decay (0 ν β β ) experiments. GERDA Phase-II will probe a significant portion of the good-fit parameter space.

  4. Observation of the decay B-->J/psietaK and search for X(3872)-->J/psieta.

    PubMed

    Aubert, B; Barate, R; Boutigny, D; Couderc, F; Gaillard, J M; Hicheur, A; Karyotakis, Y; Lees, J P; Tisserand, V; Zghiche, A; Palano, A; Pompili, A; Chen, J C; Qi, N D; Rong, G; Wang, P; Zhu, Y S; Eigen, G; Ofte, I; Stugu, B; Abrams, G S; Borgland, A W; Breon, A B; Brown, D N; Button-Shafer, J; Cahn, R N; Charles, E; Day, C T; Gill, M S; Gritsan, A V; Groysman, Y; Jacobsen, R G; Kadel, R W; Kadyk, J; Kerth, L T; Kolomensky, Yu G; Kukartsev, G; LeClerc, C; Levi, M E; Lynch, G; Mir, L M; Oddone, P J; Orimoto, T J; Pripstein, M; Roe, N A; Ronan, M T; Shelkov, V G; Telnov, A V; Wenzel, W A; Ford, K; Harrison, T J; Hawkes, C M; Morgan, S E; Watson, A T; Watson, N K; Fritsch, M; Goetzen, K; Held, T; Koch, H; Lewandowski, B; Pelizaeus, M; Steinke, M; Boyd, J T; Chevalier, N; Cottingham, W N; Kelly, M P; Latham, T E; Wilson, F F; Abe, K; Cuhadar-Donszelmann, T; Hearty, C; Mattison, T S; McKenna, J A; Thiessen, D; Kyberd, P; Teodorescu, L; Blinov, V E; Bukin, A D; Druzhinin, V P; Golubev, V B; Ivanchenko, V N; Kravchenko, E A; Onuchin, A P; Serednyakov, S I; Skovpen, Yu I; Solodov, E P; Yushkov, A N; Best, D; Bruinsma, M; Chao, M; Eschrich, I; Kirkby, D; Lankford, A J; Mandelkern, M; Mommsen, R K; Roethel, W; Stoker, D P; Buchanan, C; Hartfiel, B L; Gary, J W; Shen, B C; Wang, K; del Re, D; Hadavand, H K; Hill, E J; MacFarlane, D B; Paar, H P; Rahatlou, Sh; Sharma, V; Berryhill, J W; Campagnari, C; Dahmes, B; Levy, S L; Long, O; Lu, A; Mazur, M A; Richman, J D; Verkerke, W; Beck, T W; Eisner, A M; Heusch, C A; Lockman, W S; Schalk, T; Schmitz, R E; Schumm, B A; Seiden, A; Spradlin, P; Williams, D C; Wilson, M G; Albert, J; Chen, E; Dubois-Felsmann, G P; Dvoretskii, A; Hitlin, D G; Narsky, I; Piatenko, T; Porter, F C; Ryd, A; Samuel, A; Yang, S; Jayatilleke, S; Mancinelli, G; Meadows, B T; Sokoloff, M D; Abe, T; Blanc, F; Bloom, P; Chen, S; Clark, P J; Ford, W T; Nauenberg, U; Olivas, A; Rankin, P; Smith, J G; van Hoek, W C; Zhang, L; Harton, J L; Hu, T; Soffer, A; Toki, W H; Wilson, R J; Zeng, Q; Altenburg, D; Brandt, T; Brose, J; Colberg, T; Dickopp, M; Feltresi, E; Hauke, A; Lacker, H M; Maly, E; Müller-Pfefferkorn, R; Nogowski, R; Otto, S; Schubert, J; Schubert, K R; Schwierz, R; Spaan, B; Bernard, D; Bonneaud, G R; Brochard, F; Grenier, P; Thiebaux, Ch; Vasileiadis, G; Verderi, M; Bard, D J; Khan, A; Lavin, D; Muheim, F; Playfer, S; Andreotti, M; Azzolini, V; Bettoni, D; Bozzi, C; Calabrese, R; Cibinetto, G; Luppi, E; Negrini, M; Sarti, A; Treadwell, E; Baldini-Ferroli, R; Calcaterra, A; de Sangro, R; Finocchiaro, G; Patteri, P; Piccolo, M; Zallo, A; Buzzo, A; Capra, R; Contri, R; Crosetti, G; Lo Vetere, M; Macri, M; Monge, M R; Passaggio, S; Patrignani, C; Robutti, E; Santroni, A; Tosi, S; Bailey, S; Brandenburg, G; Morii, M; Won, E; Dubitzky, R S; Langenegger, U; Bhimji, W; Bowerman, D A; Dauncey, P D; Egede, U; Gaillard, J R; Morton, G W; Nash, J A; Taylor, G P; Grenier, G J; Lee, S J; Mallik, U; Cochran, J; Crawley, H B; Lamsa, J; Meyer, W T; Prell, S; Rosenberg, E I; Yi, J; Davier, M; Grosdidier, G; Höcker, A; Laplace, S; Le Diberder, F; Lepeltier, V; Lutz, A M; Petersen, T C; Plaszczynski, S; Schune, M H; Tantot, L; Wormser, G; Cheng, C H; Lange, D J; Simani, M C; Wright, D M; Bevan, A J; Coleman, J P; Fry, J R; Gabathuler, E; Gamet, R; Kay, M; Parry, R J; Payne, D J; Sloane, R J; Touramanis, C; Back, J J; Harrison, P F; Mohanty, G B; Brown, C L; Cowan, G; Flack, R L; Flaecher, H U; George, S; Green, M G; Kurup, A; Marker, C E; McMahon, T R; Ricciardi, S; Salvatore, F; Vaitsas, G; Winter, M A; Brown, D; Davis, C L; Allison, J; Barlow, N R; Barlow, R J; Hart, P A; Hodgkinson, M C; Lafferty, G D; Lyon, A J; Williams, J C; Farbin, A; Hulsbergen, W D; Jawahery, A; Kovalskyi, D; Lae, C K; Lillard, V; Roberts, D A; Blaylock, G; Dallapiccola, C; Flood, K T; Hertzbach, S S; Kofler, R; Koptchev, V B; Moore, T B; Saremi, S; Staengle, H; Willocq, S; Cowan, R; Sciolla, G; Taylor, F; Yamamoto, R K; Mangeol, D J J; Patel, P M; Robertson, S H; Lazzaro, A; Palombo, F; Bauer, J M; Cremaldi, L; Eschenburg, V; Godang, R; Kroeger, R; Reidy, J; Sanders, D A; Summers, D J; Zhao, H W; Brunet, S; Côté, D; Taras, P; Nicholson, H; Cartaro, C; Cavallo, N; Fabozzi, F; Gatto, C; Lista, L; Monorchio, D; Paolucci, P; Piccolo, D; Sciacca, C; Baak, M; Raven, G; Wilden, L; Jessop, C P; LoSecco, J M; Gabriel, T A; Allmendinger, T; Brau, B; Gan, K K; Honscheid, K; Hufnagel, D; Kagan, H; Kass, R; Pulliam, T; Ter-Antonyan, R; Wong, Q K; Brau, J; Frey, R; Igonkina, O; Potter, C T; Sinev, N B; Strom, D; Torrence, E; Colecchia, F; Dorigo, A; Galeazzi, F; Margoni, M; Morandin, M; Posocco, M; Rotondo, M; Simonetto, F; Stroili, R; Tiozzo, G; Voci, C; Benayoun, M; Briand, H; Chauveau, J; David, P; de la Vaissière, Ch; Del Buono, L; Hamon, O; John, M J J; Leruste, Ph; Ocariz, J; Pivk, M; Roos, L; T'Jampens, S; Therin, G; Manfredi, P F; Re, V; Behera, P K; Gladney, L; Guo, Q H; Panetta, J; Anulli, F; Biasini, M; Peruzzi, I M; Pioppi, M; Angelini, C; Batignani, G; Bettarini, S; Bondioli, M; Bucci, F; Calderini, G; Carpinelli, M; Del Gamba, V; Forti, F; Giorgi, M A; Lusiani, A; Marchiori, G; Martinez-Vidal, F; Morganti, M; Neri, N; Paoloni, E; Rama, M; Rizzo, G; Sandrelli, F; Walsh, J; Haire, M; Judd, D; Paick, K; Wagoner, D E; Danielson, N; Elmer, P; Lu, C; Miftakov, V; Olsen, J; Smith, A J S; Varnes, E W; Bellini, F; Cavoto, G; Faccini, R; Ferrarotto, F; Ferroni, F; Gaspero, M; Li Gioi, L; Mazzoni, M A; Morganti, S; Pierini, M; Piredda, G; Tehrani, F Safai; Voena, C; Christ, S; Wagner, G; Waldi, R; Adye, T; De Groot, N; Franek, B; Geddes, N I; Gopal, G P; Olaiya, E O; Xella, S M; Aleksan, R; Emery, S; Gaidot, A; Ganzhur, S F; Giraud, P F; Hamel de Monchenault, G; Kozanecki, W; Langer, M; Legendre, M; London, G W; Mayer, B; Schott, G; Vasseur, G; Yèche, Ch; Zito, M; Purohit, M V; Weidemann, A W; Yumiceva, F X; Aston, D; Bartoldus, R; Berger, N; Boyarski, A M; Buchmueller, O L; Convery, M R; Cristinziani, M; De Nardo, G; Dong, D; Dorfan, J; Dujmic, D; Dunwoodie, W; Elsen, E E; Field, R C; Glanzman, T; Gowdy, S J; Hadig, T; Halyo, V; Hryn'ova, T; Innes, W R; Kelsey, M H; Kim, P; Kocian, M L; Leith, D W G S; Libby, J; Luitz, S; Luth, V; Lynch, H L; Marsiske, H; Messner, R; Muller, D R; O'Grady, C P; Ozcan, V E; Perazzo, A; Perl, M; Petrak, S; Ratcliff, B N; Roodman, A; Salnikov, A A; Schindler, R H; Schwiening, J; Simi, G; Snyder, A; Soha, A; Stelzer, J; Su, D; Sullivan, M K; Va'vra, J; Wagner, S R; Weaver, M; Weinstein, A J R; Wisniewski, W J; Wittgen, M; Wright, D H; Young, C C; Burchat, P R; Edwards, A J; Meyer, T I; Petersen, B A; Roat, C; Ahmed, S; Alam, M S; Ernst, J A; Saeed, M A; Saleem, M; Wappler, F R; Bugg, W; Krishnamurthy, M; Spanier, S M; Eckmann, R; Kim, H; Ritchie, J L; Satpathy, A; Schwitters, R F; Izen, J M; Kitayama, I; Lou, X C; Ye, S; Bianchi, F; Bona, M; Gallo, F; Gamba, D; Borean, C; Bosisio, L; Cossutti, F; Della Ricca, G; Dittongo, S; Grancagnolo, S; Lanceri, L; Poropat, P; Vitale, L; Vuagnin, G; Panvini, R S; Banerjee, Sw; Brown, C M; Fortin, D; Jackson, P D; Kowalewski, R; Roney, J M; Band, H R; Dasu, S; Datta, M; Eichenbaum, A M; Hollar, J J; Johnson, J R; Kutter, P E; Li, H; Liu, R; Di Lodovico, F; Mihalyi, A; Mohapatra, A K; Pan, Y; Prepost, R; Sekula, S J; Tan, P; von Wimmersperg-Toeller, J H; Wu, J; Wu, S L; Yu, Z; Neal, H

    2004-07-23

    We report the observation of the B meson decay B+/- -->J/psietaK+/- and evidence for the decay B0-->J/psietaK0S, using 90 x 10(6) BB; events collected at the Upsilon(4S) resonance with the BABAR detector at the SLAC PEP-II e+e- asymmetric-energy storage ring. We obtain branching fractions of B(B+/- -->J/psietaK+/-) = [10.8 +/- 2.3(stat) +/- 2.4(syst)] x 10(-5) and B(B0-->J/psietaK0S) = [8.4 +/- 2.6(stat) +/- 2.7(syst)] x 10(-5). We search for the new narrow mass state, the X(3872), recently reported by the Belle Collaboration, in the decay B+/- -->X(3872)K+/-,X(3872)-->J/psieta and determine an upper limit of B[B +/- -->X(3872)K+/- -->J/psietaK+/-] < 7.7 x 10(-6) at 90% confidence level. Copyright 2004 The American Physical Society

  5. MiR-34b-5p Suppresses Melanoma Differentiation-Associated Gene 5 (MDA5) Signaling Pathway to Promote Avian Leukosis Virus Subgroup J (ALV-J)-Infected Cells Proliferaction and ALV-J Replication

    PubMed Central

    Li, Zhenhui; Luo, Qingbin; Xu, Haiping; Zheng, Ming; Abdalla, Bahareldin Ali; Feng, Min; Cai, Bolin; Zhang, Xiaocui; Nie, Qinghua; Zhang, Xiquan

    2017-01-01

    Avian leukosis virus subgroup J (ALV-J) is an oncogenic retrovirus that has a similar replication cycle to multiple viruses and therefore can be used as a model system for viral entry into host cells. However, there are few reports on the genes or microRNAs (miRNAs) that are responsible for the replication of ALV-J. Our previous miRNA and RNA sequencing data showed that the expression of miR-34b-5p was significantly upregulated in ALV-J-infected chicken spleens compared to non-infected chicken spleens, but melanoma differentiation-associated gene 5 (MDA5) had the opposite expression pattern. In this study, a dual-luciferase reporter assay showed that MDA5 is a direct target of miR-34b-5p. In vitro, overexpression of miR-34b-5p accelerated the proliferation of ALV-J-infected cells by inducing the progression from G2 to S phase and it promoted cell migration. Ectopic expression of MDA5 inhibited ALV-J-infected cell proliferation, the cell cycle and cell migration, and knockdown of MDA5 promoted proliferation, the cell cycle and migration. In addition, during ALV-J infections, MDA5 can detect virus invasion and it triggers the MDA5 signaling pathway. MDA5 overexpression can activate the MDA5 signaling pathway, and thus it can inhibit the mRNA and protein expression of the ALV-J env gene and it can suppress virion secretion. In contrast, in response to the knockdown of MDA5 by small interfering RNA (siRNA) or an miR-34b-5p mimic, genes in the MDA5 signaling pathway were significantly downregulated (P < 0.05), but the mRNA and protein expression of ALV-J env and the sample-to-positive ratio of virion in the supernatants were increased. This indicates that miR-34b-5p is able to trigger the MDA5 signaling pathway and affect ALV-J infections. Together, these results suggest that miR-34b-5p targets MDA5 to accelerate the proliferation and migration of ALV-J-infected cells, and it promotes ALV-J replication, via the MDA5 signaling pathway. PMID:28194372

  6. MiR-34b-5p Suppresses Melanoma Differentiation-Associated Gene 5 (MDA5) Signaling Pathway to Promote Avian Leukosis Virus Subgroup J (ALV-J)-Infected Cells Proliferaction and ALV-J Replication.

    PubMed

    Li, Zhenhui; Luo, Qingbin; Xu, Haiping; Zheng, Ming; Abdalla, Bahareldin Ali; Feng, Min; Cai, Bolin; Zhang, Xiaocui; Nie, Qinghua; Zhang, Xiquan

    2017-01-01

    Avian leukosis virus subgroup J (ALV-J) is an oncogenic retrovirus that has a similar replication cycle to multiple viruses and therefore can be used as a model system for viral entry into host cells. However, there are few reports on the genes or microRNAs (miRNAs) that are responsible for the replication of ALV-J. Our previous miRNA and RNA sequencing data showed that the expression of miR-34b-5p was significantly upregulated in ALV-J-infected chicken spleens compared to non-infected chicken spleens, but melanoma differentiation-associated gene 5 ( MDA5 ) had the opposite expression pattern. In this study, a dual-luciferase reporter assay showed that MDA5 is a direct target of miR-34b-5p. In vitro , overexpression of miR-34b-5p accelerated the proliferation of ALV-J-infected cells by inducing the progression from G2 to S phase and it promoted cell migration. Ectopic expression of MDA5 inhibited ALV-J-infected cell proliferation, the cell cycle and cell migration, and knockdown of MDA5 promoted proliferation, the cell cycle and migration. In addition, during ALV-J infections, MDA5 can detect virus invasion and it triggers the MDA5 signaling pathway. MDA5 overexpression can activate the MDA5 signaling pathway, and thus it can inhibit the mRNA and protein expression of the ALV-J env gene and it can suppress virion secretion. In contrast, in response to the knockdown of MDA5 by small interfering RNA (siRNA) or an miR-34b-5p mimic, genes in the MDA5 signaling pathway were significantly downregulated ( P < 0.05), but the mRNA and protein expression of ALV-J env and the sample-to-positive ratio of virion in the supernatants were increased. This indicates that miR-34b-5p is able to trigger the MDA5 signaling pathway and affect ALV-J infections. Together, these results suggest that miR-34b-5p targets MDA5 to accelerate the proliferation and migration of ALV-J-infected cells, and it promotes ALV-J replication, via the MDA5 signaling pathway.

  7. Worm Algorithm simulations of the hole dynamics in the t-J model

    NASA Astrophysics Data System (ADS)

    Prokof'ev, Nikolai; Ruebenacker, Oliver

    2001-03-01

    In the limit of small J << t, relevant for HTSC materials and Mott-Hubbard systems, computer simulations have to be performed for large systems and at low temperatures. Despite convincing evidence against spin-charge separation obtained by various methods for J > 0.4t there is an ongoing argument that at smaller J spin-charge separation is still possible. Worm algorithm Monte Carlo simulations of the hole Green function for 0.1 < J/t < 0.4 were performed on lattices with up to 32x32 sites, and at temperature J/T = 40 (for the largest size). Spectral analysis reveals a single, delta-function sharp quasiparticle peak at the lowest edge of the spectrum and two distinct peaks above it at all studied J. We rule out the possibility of spin-charge separation in this parameter range, and present, apparently, the hole spectral function in the thermodynamic limit.

  8. Katherine J. Chou | NREL

    Science.gov Websites

    J. Chou Photo of Katherine J. Chou Katherine Chou Microbial Physiology & Engineering , Clostridium thermocellum, through metabolic engineering. "Biological Electron Transfer and Catalysis principles governing substrate utilization. "Advance Biofuels from Cellulose via Genetic Engineering of

  9. Neuroanatomical characterization of the cellular and axonal architecture of subcortical band heterotopia in the BXD29-Tlr4lps-2J/J mouse cortex.

    PubMed

    Ramos, Raddy L; Toia, Alyssa R; Pasternack, Daniel M; Dotzler, Timothy P; Cuoco, Joshua A; Esposito, Anthony W; Le, Megan M; Parker, Alexander K; Goodman, Jeffrey H; Sarkisian, Matthew R

    2016-11-19

    Subcortical band heterotopia (SBH) are malformations of the human cerebral cortex typically associated with epilepsy and cognitive delay/disability. Rodent models of SBH have demonstrated strong face validity as they are accompanied by both cognitive deficits and spontaneous seizures or reduced seizure threshold. BXD29-Tlr4 lps-2J /J recombinant inbred mice display striking bilateral SBH, partial callosal agenesis, morphological changes in subcortical structures of the auditory pathway, and display sensory deficits in behavioral tests (Rosen et al., 2013; Truong et al., 2013, 2015). Surprisingly, these mice show no cognitive deficits and have a higher seizure threshold to chemi-convulsive treatment (Gabel et al., 2013) making them different than other rodent SBH models described previously. In the present report, we perform a detailed characterization of the cellular and axonal constituents of SBH in BXD29-Tlr4 lps-2J /J mice and demonstrate that various types of interneurons and glia as well as cortical and subcortical projections are found in SBH. In addition, the length of neuronal cilia was reduced in SBH compared to neurons in the overlying and adjacent normotopic cortex. Finally, we describe additional and novel malformations of the hippocampus and neocortex present in BXD29-Tlr4 lps-2J /J mice. Together, our findings in BXD29-Tlr4 lps-2J /J mice are discussed in the context of the known neuroanatomy and phenotype of other SBH rodent models. Copyright © 2016 IBRO. Published by Elsevier Ltd. All rights reserved.

  10. Dalitz plot analyses of J / ψ → π + π - π 0 , J / ψ → K + K - π 0 , and J / ψ → K s 0 K ± π ∓ produced via e + e - annihilation with initial-state radiation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lees, J. P.; Poireau, V.; Tisserand, V.

    Here, we study the processes e +e - → γ ISR J/ψ , where J/ψ → π +π -π 0, J/ψ → K +K -π 0 , and J / ψ → Kmore » $$0\\atop{S}$$ K ± π ∓ using a data sample of 519 fb -1 recorded with the BABAR detector operating at the SLAC PEP-II asymmetric-energy e +e - collider at center-of-mass energies at and near the Υ (nS) (n = 2 , 3 , 4) resonances. We measure the ratio of branching fractions R 1 = $$B(J/ψ →K^+K^- π^0)\\atop{B(J/ψ →π^+π^- π^0)}$$ and R 2= $$B(J/ψ →K^0_SK^±π^∓)\\atop{B(J/ψ →π^+π^- π^0)}$$. We perform Dalitz plot analyses of the three J/ψ decay modes and measure fractions for resonances contributing to the decays. We also analyze the J/ψ → $π^+π^- π^0$ decay using the Veneziano model. We observe structures compatible with the presence of ρ (1450) in all three J/ψ decay modes and measure the relative branching fraction: R (p(1450)) = $$Bp(1450)→K^+K^-)\\atop{B(p(1450)→π^+π^-)}$$ +0.307 ± 0.084 (stat) ± 0.082 (sys).« less

  11. Dalitz plot analyses of J / ψ → π + π - π 0 , J / ψ → K + K - π 0 , and J / ψ → K s 0 K ± π ∓ produced via e + e - annihilation with initial-state radiation

    DOE PAGES

    Lees, J. P.; Poireau, V.; Tisserand, V.; ...

    2017-04-10

    Here, we study the processes e +e - → γ ISR J/ψ , where J/ψ → π +π -π 0, J/ψ → K +K -π 0 , and J / ψ → Kmore » $$0\\atop{S}$$ K ± π ∓ using a data sample of 519 fb -1 recorded with the BABAR detector operating at the SLAC PEP-II asymmetric-energy e +e - collider at center-of-mass energies at and near the Υ (nS) (n = 2 , 3 , 4) resonances. We measure the ratio of branching fractions R 1 = $$B(J/ψ →K^+K^- π^0)\\atop{B(J/ψ →π^+π^- π^0)}$$ and R 2= $$B(J/ψ →K^0_SK^±π^∓)\\atop{B(J/ψ →π^+π^- π^0)}$$. We perform Dalitz plot analyses of the three J/ψ decay modes and measure fractions for resonances contributing to the decays. We also analyze the J/ψ → $π^+π^- π^0$ decay using the Veneziano model. We observe structures compatible with the presence of ρ (1450) in all three J/ψ decay modes and measure the relative branching fraction: R (p(1450)) = $$Bp(1450)→K^+K^-)\\atop{B(p(1450)→π^+π^-)}$$ +0.307 ± 0.084 (stat) ± 0.082 (sys).« less

  12. 78 FR 28719 - Special Conditions: Cessna Aircraft Company, Model J182T; Diesel Cycle Engine Installation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-16

    ...; Special Conditions No. 23-259-SC] Special Conditions: Cessna Aircraft Company, Model J182T; Diesel Cycle..., air cooled, diesel cycle engine that uses turbine (jet) fuel. The Model No. J182T, which is a... engine airplane with a cantilever high wing, with the SMA SR305- 230E-C1 diesel cycle engine and...

  13. Numerical study of incommensurate and decoupled phases of spin-1/2 chains with isotropic exchange J 1, J 2 between first and second neighbors

    NASA Astrophysics Data System (ADS)

    Soos, Zoltán G.; Parvej, Aslam; Kumar, Manoranjan

    2016-05-01

    The spin-1/2 chain with isotropic exchange J 1, J 2  >  0 between first and second neighbors is frustrated for either sign of J 1 and has a singlet ground state (GS) for J 1/J 2  ⩾  -4. Its rich quantum phase diagram supports gapless, gapped, commensurate (C), incommensurate (IC) and other phases. Critical points J 1/J 2 are evaluated using exact diagonalization and density matrix renormalization group calculations. The wave vector q G of spin correlations is related to GS degeneracy and obtained as the peak of the spin structure factor S(q). Variable q G indicates IC phases in two J 1/J 2 intervals, [-4, -  1.24] and [0.44, 2], and a C-IC point at J 1/J 2  =  2. The decoupled C phase in [-1.24, 0.44] has constant q G  =  π/2, nondegenerate GS, and a lowest triplet state with broken spin density on sublattices of odd and even numbered sites. The lowest triplet and singlet excitations, E m and E σ , are degenerate in finite systems at specific frustration J 1/J 2. Level crossing extrapolates in the thermodynamic limit to the same critical points as q G. The S(q) peak diverges at q G  =  π in the gapless phase with J 1/J 2  >  4.148 and quasi-long-range order (QLRO(π)). S(q) diverges at  ±π/2 in the decoupled phase with QLRO(π/2), but is finite in gapped phases with finite-range correlations. Numerical results and field theory agree at small J 2/J 1 but disagree for the decoupled phase with weak exchange J 1 between sublattices. Two related models are summarized: one has an exact gapless decoupled phase with QLRO(π/2) and no IC phases; the other has a single IC phase without a decoupled phase in between.

  14. A SELF-CONSISTENT EXPLANATION OF TeV EMISSIONS FROM HESS J1640-465 AND HESS J1641-463

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tang, Yunyong; Yang, Chuyuan; Wang, Jiancheng

    2015-10-10

    The bright TeV source HESS J1640-465 is positionally coincident with the young supernova remnant (SNR) G338.3-0.0, and the nearby HESS J1641-463 with TeV gamma-ray emission seems to be closely associated with it. Based on the nonlinear diffusion shock acceleration model, we explore the emission from these two TeV sources, the particle diffusion is assumed to be different inside and outside the absorbing boundary of the particles accelerated in the SNR shock. The results indicate that (1) the GeV–TeV emission from the region of the HESS J1640-465 is produced as a result of the particle acceleration inside the SNR G338.3-0.0 andmore » (2) the runaway cosmic-ray particles outside the SNR are interacting with the nearby dense molecular cloud (MC) at the region of the HESS J1641-463, corresponding π{sup 0} decay gamma-ray in proton–proton collision contribute to the TeV emission from the HESS J1641-463. Also, we investigate the possible X-ray emission in MC from the synchrotron procedure by secondary e{sup ±} produced through escaped protons interaction with the MC.« less

  15. Evidence for the decay B0→J/ψω and measurement of the relative branching fractions of Bs0 meson decays to J/ψη and J/ψη'

    NASA Astrophysics Data System (ADS)

    Aaij, R.; Abellan Beteta, C.; Adametz, A.; Adeva, B.; Adinolfi, M.; Adrover, C.; Affolder, A.; Ajaltouni, Z.; Albrecht, J.; Alessio, F.; Alexander, M.; Ali, S.; Alkhazov, G.; Alvarez Cartelle, P.; Alves, A. A.; Amato, S.; Amhis, Y.; Anderlini, L.; Anderson, J.; Appleby, R. B.; Aquines Gutierrez, O.; Archilli, F.; Artamonov, A.; Artuso, M.; Aslanides, E.; Auriemma, G.; Bachmann, S.; Back, J. J.; Baesso, C.; Balagura, V.; Baldini, W.; Barlow, R. J.; Barschel, C.; Barsuk, S.; Barter, W.; Bates, A.; Bauer, Th.; Bay, A.; Beddow, J.; Bediaga, I.; Belogurov, S.; Belous, K.; Belyaev, I.; Ben-Haim, E.; Benayoun, M.; Bencivenni, G.; Benson, S.; Benton, J.; Berezhnoy, A.; Bernet, R.; Bettler, M.-O.; van Beuzekom, M.; Bien, A.; Bifani, S.; Bird, T.; Bizzeti, A.; Bjørnstad, P. M.; Blake, T.; Blanc, F.; Blanks, C.; Blouw, J.; Blusk, S.; Bobrov, A.; Bocci, V.; Bondar, A.; Bondar, N.; Bonivento, W.; Borghi, S.; Borgia, A.; Bowcock, T. J. V.; Bozzi, C.; Brambach, T.; van den Brand, J.; Bressieux, J.; Brett, D.; Britsch, M.; Britton, T.; Brook, N. H.; Brown, H.; Büchler-Germann, A.; Burducea, I.; Bursche, A.; Buytaert, J.; Cadeddu, S.; Callot, O.; Calvi, M.; Calvo Gomez, M.; Camboni, A.; Campana, P.; Carbone, A.; Carboni, G.; Cardinale, R.; Cardini, A.; Carson, L.; Carvalho Akiba, K.; Casse, G.; Cattaneo, M.; Cauet, Ch.; Charles, M.; Charpentier, Ph.; Chen, P.; Chiapolini, N.; Chrzaszcz, M.; Ciba, K.; Cid Vidal, X.; Ciezarek, G.; Clarke, P. E. L.; Clemencic, M.; Cliff, H. V.; Closier, J.; Coca, C.; Coco, V.; Cogan, J.; Cogneras, E.; Collins, P.; Comerma-Montells, A.; Contu, A.; Cook, A.; Coombes, M.; Corti, G.; Couturier, B.; Cowan, G. A.; Craik, D.; Cunliffe, S.; Currie, R.; D'Ambrosio, C.; David, P.; David, P. N. Y.; De Bonis, I.; De Bruyn, K.; De Capua, S.; De Cian, M.; De Miranda, J. M.; De Paula, L.; De Simone, P.; Decamp, D.; Deckenhoff, M.; Degaudenzi, H.; Del Buono, L.; Deplano, C.; Derkach, D.; Deschamps, O.; Dettori, F.; Dickens, J.; Dijkstra, H.; Diniz Batista, P.; Domingo Bonal, F.; Donleavy, S.; Dordei, F.; Dosil Suárez, A.; Dossett, D.; Dovbnya, A.; Dupertuis, F.; Dzhelyadin, R.; Dziurda, A.; Dzyuba, A.; Easo, S.; Egede, U.; Egorychev, V.; Eidelman, S.; van Eijk, D.; Eisele, F.; Eisenhardt, S.; Ekelhof, R.; Eklund, L.; El Rifai, I.; Elsasser, Ch.; Elsby, D.; Esperante Pereira, D.; Falabella, A.; Färber, C.; Fardell, G.; Farinelli, C.; Farry, S.; Fave, V.; Fernandez Albor, V.; Ferreira Rodrigues, F.; Ferro-Luzzi, M.; Filippov, S.; Fitzpatrick, C.; Fontana, M.; Fontanelli, F.; Forty, R.; Francisco, O.; Frank, M.; Frei, C.; Frosini, M.; Furcas, S.; Gallas Torreira, A.; Galli, D.; Gandelman, M.; Gandini, P.; Gao, Y.; Garnier, J.-C.; Garofoli, J.; Garra Tico, J.; Garrido, L.; Gaspar, C.; Gauld, R.; Gersabeck, E.; Gersabeck, M.; Gershon, T.; Ghez, Ph.; Gibson, V.; Gligorov, V. V.; Göbel, C.; Golubkov, D.; Golutvin, A.; Gomes, A.; Gordon, H.; Grabalosa Gándara, M.; Graciani Diaz, R.; Granado Cardoso, L. A.; Graugés, E.; Graziani, G.; Grecu, A.; Greening, E.; Gregson, S.; Grünberg, O.; Gui, B.; Gushchin, E.; Guz, Yu.; Gys, T.; Hadjivasiliou, C.; Haefeli, G.; Haen, C.; Haines, S. C.; Hall, S.; Hampson, T.; Hansmann-Menzemer, S.; Harnew, N.; Harnew, S. T.; Harrison, J.; Harrison, P. F.; Hartmann, T.; He, J.; Heijne, V.; Hennessy, K.; Henrard, P.; Hernando Morata, J. A.; van Herwijnen, E.; Hicks, E.; Hill, D.; Hoballah, M.; Hopchev, P.; Hulsbergen, W.; Hunt, P.; Huse, T.; Hussain, N.; Huston, R. S.; Hutchcroft, D.; Hynds, D.; Iakovenko, V.; Ilten, P.; Imong, J.; Jacobsson, R.; Jaeger, A.; Jahjah Hussein, M.; Jans, E.; Jansen, F.; Jaton, P.; Jean-Marie, B.; Jing, F.; John, M.; Johnson, D.; Jones, C. R.; Jost, B.; Kaballo, M.; Kandybei, S.; Karacson, M.; Karbach, M.; Keaveney, J.; Kenyon, I. R.; Kerzel, U.; Ketel, T.; Keune, A.; Khanji, B.; Kim, Y. M.; Kochebina, O.; Komarov, I.; Komarov, V.; Koopman, R. F.; Koppenburg, P.; Korolev, M.; Kozlinskiy, A.; Kravchuk, L.; Kreplin, K.; Kreps, M.; Krocker, G.; Krokovny, P.; Kruse, F.; Kucharczyk, M.; Kudryavtsev, V.; Kvaratskheliya, T.; La Thi, V. N.; Lacarrere, D.; Lafferty, G.; Lai, A.; Lambert, D.; Lambert, R. W.; Lanciotti, E.; Lanfranchi, G.; Langenbruch, C.; Latham, T.; Lazzeroni, C.; Le Gac, R.; van Leerdam, J.; Lees, J.-P.; Lefèvre, R.; Leflat, A.; Lefrançois, J.; Leroy, O.; Lesiak, T.; Li, L.; Li, Y.; Li Gioi, L.; Liles, M.; Lindner, R.; Linn, C.; Liu, B.; Liu, G.; von Loeben, J.; Lopes, J. H.; Lopez Asamar, E.; Lopez-March, N.; Lu, H.; Luisier, J.; Mac Raighne, A.; Machefert, F.; Machikhiliyan, I. V.; Maciuc, F.; Maev, O.; Magnin, J.; Maino, M.; Malde, S.; Manca, G.; Mancinelli, G.; Mangiafave, N.; Marconi, U.; Märki, R.; Marks, J.; Martellotti, G.; Martens, A.; Martin, L.; Martín Sánchez, A.; Martinelli, M.; Martinez Santos, D.; Massafferri, A.; Mathe, Z.; Matteuzzi, C.; Matveev, M.; Maurice, E.; Mazurov, A.; McCarthy, J.; McGregor, G.; McNulty, R.; Meissner, M.; Merk, M.; Merkel, J.; Milanes, D. A.; Minard, M.-N.; Molina Rodriguez, J.; Monteil, S.; Moran, D.; Morawski, P.; Mountain, R.; Mous, I.; Muheim, F.; Müller, K.; Muresan, R.; Muryn, B.; Muster, B.; Mylroie-Smith, J.; Naik, P.; Nakada, T.; Nandakumar, R.; Nasteva, I.; Needham, M.; Neufeld, N.; Nguyen, A. D.; Nguyen-Mau, C.; Nicol, M.; Niess, V.; Nikitin, N.; Nikodem, T.; Nomerotski, A.; Novoselov, A.; Oblakowska-Mucha, A.; Obraztsov, V.; Oggero, S.; Ogilvy, S.; Okhrimenko, O.; Oldeman, R.; Orlandea, M.; Otalora Goicochea, J. M.; Owen, P.; Pal, B. K.; Palano, A.; Palutan, M.; Panman, J.; Papanestis, A.; Pappagallo, M.; Parkes, C.; Parkinson, C. J.; Passaleva, G.; Patel, G. D.; Patel, M.; Patrick, G. N.; Patrignani, C.; Pavel-Nicorescu, C.; Pazos Alvarez, A.; Pellegrino, A.; Penso, G.; Pepe Altarelli, M.; Perazzini, S.; Perego, D. L.; Perez Trigo, E.; Pérez-Calero Yzquierdo, A.; Perret, P.; Perrin-Terrin, M.; Pessina, G.; Petridis, K.; Petrolini, A.; Phan, A.; Picatoste Olloqui, E.; Pie Valls, B.; Pietrzyk, B.; Pilař, T.; Pinci, D.; Playfer, S.; Plo Casasus, M.; Polci, F.; Polok, G.; Poluektov, A.; Polycarpo, E.; Popov, D.; Popovici, B.; Potterat, C.; Powell, A.; Prisciandaro, J.; Pugatch, V.; Puig Navarro, A.; Qian, W.; Rademacker, J. H.; Rakotomiaramanana, B.; Rangel, M. S.; Raniuk, I.; Rauschmayr, N.; Raven, G.; Redford, S.; Reid, M. M.; dos Reis, A. C.; Ricciardi, S.; Richards, A.; Rinnert, K.; Rives Molina, V.; Roa Romero, D. A.; Robbe, P.; Rodrigues, E.; Rodriguez Perez, P.; Rogers, G. J.; Roiser, S.; Romanovsky, V.; Romero Vidal, A.; Rouvinet, J.; Ruf, T.; Ruiz, H.; Sabatino, G.; Saborido Silva, J. J.; Sagidova, N.; Sail, P.; Saitta, B.; Salzmann, C.; Sanmartin Sedes, B.; Sannino, M.; Santacesaria, R.; Santamarina Rios, C.; Santinelli, R.; Santovetti, E.; Sapunov, M.; Sarti, A.; Satriano, C.; Satta, A.; Savrie, M.; Savrina, D.; Schaack, P.; Schiller, M.; Schindler, H.; Schleich, S.; Schlupp, M.; Schmelling, M.; Schmidt, B.; Schneider, O.; Schopper, A.; Schune, M.-H.; Schwemmer, R.; Sciascia, B.; Sciubba, A.; Seco, M.; Semennikov, A.; Senderowska, K.; Sepp, I.; Serra, N.; Serrano, J.; Seyfert, P.; Shapkin, M.; Shapoval, I.; Shatalov, P.; Shcheglov, Y.; Shears, T.; Shekhtman, L.; Shevchenko, O.; Shevchenko, V.; Shires, A.; Silva Coutinho, R.; Skwarnicki, T.; Smith, N. A.; Smith, E.; Smith, M.; Sobczak, K.; Soler, F. J. P.; Solomin, A.; Soomro, F.; Souza, D.; Souza De Paula, B.; Spaan, B.; Sparkes, A.; Spradlin, P.; Stagni, F.; Stahl, S.; Steinkamp, O.; Stoica, S.; Stone, S.; Storaci, B.; Straticiuc, M.; Straumann, U.; Subbiah, V. K.; Swientek, S.; Szczekowski, M.; Szczypka, P.; Szumlak, T.; T'Jampens, S.; Teklishyn, M.; Teodorescu, E.; Teubert, F.; Thomas, C.; Thomas, E.; van Tilburg, J.; Tisserand, V.; Tobin, M.; Tolk, S.; Topp-Joergensen, S.; Torr, N.; Tournefier, E.; Tourneur, S.; Tran, M. T.; Tsaregorodtsev, A.; Tuning, N.; Ubeda Garcia, M.; Ukleja, A.; Urner, D.; Uwer, U.; Vagnoni, V.; Valenti, G.; Vazquez Gomez, R.; Vazquez Regueiro, P.; Vecchi, S.; Velthuis, J. J.; Veltri, M.; Veneziano, G.; Vesterinen, M.; Viaud, B.; Videau, I.; Vieira, D.; Vilasis-Cardona, X.; Visniakov, J.; Vollhardt, A.; Volyanskyy, D.; Voong, D.; Vorobyev, A.; Vorobyev, V.; Voss, H.; Voß, C.; Waldi, R.; Wallace, R.; Wandernoth, S.; Wang, J.; Ward, D. R.; Watson, N. K.; Webber, A. D.; Websdale, D.; Whitehead, M.; Wicht, J.; Wiedner, D.; Wiggers, L.; Wilkinson, G.; Williams, M. P.; Williams, M.; Wilson, F. F.; Wishahi, J.; Witek, M.; Witzeling, W.; Wotton, S. A.; Wright, S.; Wu, S.; Wyllie, K.; Xie, Y.; Xing, F.; Xing, Z.; Yang, Z.; Young, R.; Yuan, X.; Yushchenko, O.; Zangoli, M.; Zavertyaev, M.; Zhang, F.; Zhang, L.; Zhang, W. C.; Zhang, Y.; Zhelezov, A.; Zhong, L.; Zvyagin, A.; LHCb Collaboration

    2013-02-01

    First evidence of the B0→J/ψω decay is found and the Bs0→J/ψη and Bs0→J/ψη' decays are studied using a dataset corresponding to an integrated luminosity of 1.0 fb-1 collected by the LHCb experiment in proton-proton collisions at a centre-of-mass energy of √{s}=7 TeV. The branching fractions of these decays are measured relative to that of the B0→J/ψρ0 decay: {B(B0→J/ψω)}/{B(B0→J/ψρ0)}=0.89±0.19(stat)-0.13+0.07(syst), {B(B}/{s0→J/ψη)B(B0→J/ψρ0)}=14.0±1.2(stat)-1.5+1.1(syst)-1.0+1.1(fd/fs), {B(B}/{s0→J/ψη')B(B0→J/ψρ0)}=12.7±1.1(stat)-1.3+0.5(syst)-0.9+1.0(fd/fs), where the last uncertainty is due to the knowledge of fd/fs, the ratio of b-quark hadronization factors that accounts for the different production rate of B0 and Bs0 mesons. The ratio of the branching fractions of Bs0→J/ψη' and Bs0→J/ψη decays is measured to be {B(B}/{s0→J/ψη')B(Bs0→J/ψη)}=0.90±0.09(stat)-0.02+0.06(syst).

  16. Sodium caseinate induces increased survival in leukaemic mouse J774 model.

    PubMed

    Córdova-Galaviz, Yolanda; Ledesma-Martínez, Edgar; Aguíñiga-Sánchez, Itzen; Soldevila-Melgarejo, Gloria; Soto-Cruz, Isabel; Weiss-Steider, Benny; Santiago-Osorio, Edelmiro

    2014-01-01

    Acute myeloid leukaemia is a neoplastic disease of haematopoietic stem cells. Although there have been recent advances regarding its treatment, mortality remains high. Consequently, therapeutic alternatives continue to be explored. In the present report, we present evidence that sodium caseinate (CasNa), a salt of the principal protein in milk, may possess important anti-leukaemic properties. J774 leukaemia macrophage-like cells were cultured with CasNa and proliferation, viability and differentiation were evaluated. These cells were also inoculated into BALB/c mice as a model of leukemia. We demonstrated that CasNa inhibits the in vitro proliferation and reduces viability of J774 cells, and leads to increased survival in vivo in a leukaemic mouse model. These data indicate that CasNa may be useful in leukaemia therapy. Copyright © 2014 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.

  17. My Personal Comments on J-PARC

    NASA Astrophysics Data System (ADS)

    Nagamiya, Shoji

    In this talk I present four topics excluding scientific aspects and/or a general overview of J-PARC, which will be described by the next speaker (J. M. Poutisou). Instead, I describe firstly a brief history of how J-PARC was born, as a view from me. Secondly the effects from two major accidents at J-PARC, the earthquake and the radioactive material leak accident, are described. Thirdly, I describe the future 5-year plan. Finally in the fourth, I would like to emphasize the importance of the internationalization at J-PARC.

  18. SlideJ: An ImageJ plugin for automated processing of whole slide images.

    PubMed

    Della Mea, Vincenzo; Baroni, Giulia L; Pilutti, David; Di Loreto, Carla

    2017-01-01

    The digital slide, or Whole Slide Image, is a digital image, acquired with specific scanners, that represents a complete tissue sample or cytological specimen at microscopic level. While Whole Slide image analysis is recognized among the most interesting opportunities, the typical size of such images-up to Gpixels- can be very demanding in terms of memory requirements. Thus, while algorithms and tools for processing and analysis of single microscopic field images are available, Whole Slide images size makes the direct use of such tools prohibitive or impossible. In this work a plugin for ImageJ, named SlideJ, is proposed with the objective to seamlessly extend the application of image analysis algorithms implemented in ImageJ for single microscopic field images to a whole digital slide analysis. The plugin has been complemented by examples of macro in the ImageJ scripting language to demonstrate its use in concrete situations.

  19. SlideJ: An ImageJ plugin for automated processing of whole slide images

    PubMed Central

    Baroni, Giulia L.; Pilutti, David; Di Loreto, Carla

    2017-01-01

    The digital slide, or Whole Slide Image, is a digital image, acquired with specific scanners, that represents a complete tissue sample or cytological specimen at microscopic level. While Whole Slide image analysis is recognized among the most interesting opportunities, the typical size of such images—up to Gpixels- can be very demanding in terms of memory requirements. Thus, while algorithms and tools for processing and analysis of single microscopic field images are available, Whole Slide images size makes the direct use of such tools prohibitive or impossible. In this work a plugin for ImageJ, named SlideJ, is proposed with the objective to seamlessly extend the application of image analysis algorithms implemented in ImageJ for single microscopic field images to a whole digital slide analysis. The plugin has been complemented by examples of macro in the ImageJ scripting language to demonstrate its use in concrete situations. PMID:28683129

  20. Competing orders in the Hofstadter t -J model

    NASA Astrophysics Data System (ADS)

    Tu, Wei-Lin; Schindler, Frank; Neupert, Titus; Poilblanc, Didier

    2018-01-01

    The Hofstadter model describes noninteracting fermions on a lattice in the presence of an external magnetic field. Motivated by the plethora of solid-state phases emerging from electron interactions, we consider an interacting version of the Hofstadter model, including a Hubbard repulsion U . We investigate this model in the large-U limit corresponding to a t -J Hamiltonian with an external (orbital) magnetic field. By using renormalized mean-field theory supplemented by exact diagonalization calculations of small clusters, we find evidence for competing symmetry-breaking phases, exhibiting (possibly coexisting) charge, bond, and superconducting orders. Topological properties of the states are also investigated, and some of our results are compared to related experiments involving ultracold atoms loaded on optical lattices in the presence of a synthetic gauge field.

  1. 1. Photocopied December 1977, from original in 'Report of J.B.J.,'Vol. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Photocopied December 1977, from original in 'Report of J.B.J.,'Vol. I, Jervis Library. ELEVATION OF SING SING KILL BRIDGE, SHOWING ORIGINAL PLAN FOR AN 80-FOOT ARCH. - Old Croton Aqueduct, Sing Sing Kill Bridge, Spanning Aqueduct Street & Broadway, Ossining, Westchester County, NY

  2. Nicholas J. Nagle | NREL

    Science.gov Websites

    presentation. Featured Publications "Impact of biomass processing, blending and densification, on J. Nagle Photo of Nicholas J. Nagle Nicholas Nagle Researcher IV-Chemical Engineering Nick.Nagle impact on lignin upgrading post conversion. As feedstocks rapidly evolve into new formats, such as

  3. J-2X Abort System Development

    NASA Technical Reports Server (NTRS)

    Santi, Louis M.; Butas, John P.; Aguilar, Robert B.; Sowers, Thomas S.

    2008-01-01

    The J-2X is an expendable liquid hydrogen (LH2)/liquid oxygen (LOX) gas generator cycle rocket engine that is currently being designed as the primary upper stage propulsion element for the new NASA Ares vehicle family. The J-2X engine will contain abort logic that functions as an integral component of the Ares vehicle abort system. This system is responsible for detecting and responding to conditions indicative of impending Loss of Mission (LOM), Loss of Vehicle (LOV), and/or catastrophic Loss of Crew (LOC) failure events. As an earth orbit ascent phase engine, the J-2X is a high power density propulsion element with non-negligible risk of fast propagation rate failures that can quickly lead to LOM, LOV, and/or LOC events. Aggressive reliability requirements for manned Ares missions and the risk of fast propagating J-2X failures dictate the need for on-engine abort condition monitoring and autonomous response capability as well as traditional abort agents such as the vehicle computer, flight crew, and ground control not located on the engine. This paper describes the baseline J-2X abort subsystem concept of operations, as well as the development process for this subsystem. A strategy that leverages heritage system experience and responds to an evolving engine design as well as J-2X specific test data to support abort system development is described. The utilization of performance and failure simulation models to support abort system sensor selection, failure detectability and discrimination studies, decision threshold definition, and abort system performance verification and validation is outlined. The basis for abort false positive and false negative performance constraints is described. Development challenges associated with information shortfalls in the design cycle, abort condition coverage and response assessment, engine-vehicle interface definition, and abort system performance verification and validation are also discussed.

  4. Neuronal Tryptophan Hydroxylase Expression in BALB/cJ and C57Bl/6J Mice

    PubMed Central

    Bach, Helene; Arango, Victoria; Huang, Yung-Yu; Leong, Sharlene; Mann, J. John; Underwood, Mark D.

    2014-01-01

    BALB/c is an inbred stress-sensitive mouse strain exhibiting low brain serotonin (5-HT) content and a 5-HT biosynthetic enzyme tryptophan hydroxylase (Tph2) variant reported to have lower catalytic activity compared to other inbred base strains. To evaluate other mechanisms that may explain low 5-HT, we compared BALB/cJ mice and a control inbred strain C57Bl/6J mice, for expression of Tph2 mRNA, TPH2 protein and regional levels of 5-HT and its metabolite 5-hydroxyindoleacetic acid (5-HIAA). Tph2 mRNA and TPH2 protein in brainstem dorsal raphe nuclei (DRN) was assayed by in situ hybridization and immunocytochemistry respectively. 5-HT and 5-HIAA were determined by high pressure liquid chromatography (HPLC). BALB/cJ mice had 20% less Tph2 mRNA and 28% fewer TPH2 immunolabeled neurons than C57Bl/6J mice (t = -2.59, p = 0.02). The largest difference in Tph2 transcript expression was in rostral DRN (t = 2.731, p = 0.008). 5-HT was 15% lower in the midbrain of BALB/cJ compared to C57Bl/6J mice (p < 0.05). The behavioral differences in BALB/cJ mice relative to the C57Bl/6J strain may be due in part, to fewer 5-HT neurons and lower Tph2 gene expression resulting in less 5-HT neurotransmission. Future studies quantifying expression per neuron are needed to determine whether less expression is explained by fewer neurons or also less expression per neuron, or both. PMID:21740442

  5. Neuronal tryptophan hydroxylase expression in BALB/cJ and C57Bl/6J mice.

    PubMed

    Bach, Helene; Arango, Victoria; Huang, Yung-Yu; Leong, Sharlene; Mann, J John; Underwood, Mark D

    2011-09-01

    BALB/c is an inbred stress-sensitive mouse strain exhibiting low brain serotonin (5-HT) content and a 5-HT biosynthetic enzyme tryptophan hydroxylase (Tph2) variant reported to have lower catalytic activity compared with other inbred base strains. To evaluate other mechanisms that may explain low 5-HT, we compared BALB/cJ mice and a control inbred strain C57Bl/6J mice, for expression of Tph2 mRNA, TPH2 protein and regional levels of 5-HT and its metabolite 5-hydroxyindoleacetic acid. Tph2 mRNA and TPH2 protein in brainstem dorsal raphe nuclei was assayed by in situ hybridization and immunocytochemistry respectively. 5-HT and 5-hydroxyindoleacetic acid were determined by HPLC. BALB/cJ mice had 20% less Tph2 mRNA and 28% fewer TPH2 immunolabeled neurons than C57Bl/6J mice (t = -2.59, p = 0.02). The largest difference in Tph2 transcript expression was in rostral dorsal raphe nuclei (t = 2.731, p = 0.008). 5-HT was 15% lower in the midbrain and 18% lower in the cerebral cortex of BALB/cJ compared with C57Bl/6J mice (p < 0.05). The behavioral differences in BALB/cJ mice relative to the C57Bl/6J strain may be due in part, to fewer 5-HT neurons and lower Tph2 gene expression resulting in less 5-HT neurotransmission. Future studies quantifying expression per neuron are needed to determine whether less expression is explained by fewer neurons or also less expression per neuron, or both. © 2011 The Authors. Journal of Neurochemistry © 2011 International Society for Neurochemistry.

  6. Evidence for the decay B0→J/ψω and measurement of the relative branching fractions of Bs0 meson decays to J/ψη and J/ψη‧

    NASA Astrophysics Data System (ADS)

    LHCb Collaboration; Aaij, R.; Abellan Beteta, C.; Adametz, A.; Adeva, B.; Adinolfi, M.; Adrover, C.; Affolder, A.; Ajaltouni, Z.; Albrecht, J.; Alessio, F.; Alexander, M.; Ali, S.; Alkhazov, G.; Alvarez Cartelle, P.; Alves, A. A.; Amato, S.; Amhis, Y.; Anderlini, L.; Anderson, J.; Appleby, R. B.; Aquines Gutierrez, O.; Archilli, F.; Artamonov, A.; Artuso, M.; Aslanides, E.; Auriemma, G.; Bachmann, S.; Back, J. J.; Baesso, C.; Balagura, V.; Baldini, W.; Barlow, R. J.; Barschel, C.; Barsuk, S.; Barter, W.; Bates, A.; Bauer, Th.; Bay, A.; Beddow, J.; Bediaga, I.; Belogurov, S.; Belous, K.; Belyaev, I.; Ben-Haim, E.; Benayoun, M.; Bencivenni, G.; Benson, S.; Benton, J.; Berezhnoy, A.; Bernet, R.; Bettler, M.-O.; van Beuzekom, M.; Bien, A.; Bifani, S.; Bird, T.; Bizzeti, A.; Bjørnstad, P. M.; Blake, T.; Blanc, F.; Blanks, C.; Blouw, J.; Blusk, S.; Bobrov, A.; Bocci, V.; Bondar, A.; Bondar, N.; Bonivento, W.; Borghi, S.; Borgia, A.; Bowcock, T. J. V.; Bozzi, C.; Brambach, T.; van den Brand, J.; Bressieux, J.; Brett, D.; Britsch, M.; Britton, T.; Brook, N. H.; Brown, H.; Büchler-Germann, A.; Burducea, I.; Bursche, A.; Buytaert, J.; Cadeddu, S.; Callot, O.; Calvi, M.; Calvo Gomez, M.; Camboni, A.; Campana, P.; Carbone, A.; Carboni, G.; Cardinale, R.; Cardini, A.; Carson, L.; Carvalho Akiba, K.; Casse, G.; Cattaneo, M.; Cauet, Ch.; Charles, M.; Charpentier, Ph.; Chen, P.; Chiapolini, N.; Chrzaszcz, M.; Ciba, K.; Cid Vidal, X.; Ciezarek, G.; Clarke, P. E. L.; Clemencic, M.; Cliff, H. V.; Closier, J.; Coca, C.; Coco, V.; Cogan, J.; Cogneras, E.; Collins, P.; Comerma-Montells, A.; Contu, A.; Cook, A.; Coombes, M.; Corti, G.; Couturier, B.; Cowan, G. A.; Craik, D.; Cunliffe, S.; Currie, R.; D'Ambrosio, C.; David, P.; David, P. N. Y.; De Bonis, I.; De Bruyn, K.; De Capua, S.; De Cian, M.; De Miranda, J. M.; De Paula, L.; De Simone, P.; Decamp, D.; Deckenhoff, M.; Degaudenzi, H.; Del Buono, L.; Deplano, C.; Derkach, D.; Deschamps, O.; Dettori, F.; Dickens, J.; Dijkstra, H.; Diniz Batista, P.; Domingo Bonal, F.; Donleavy, S.; Dordei, F.; Dosil Suárez, A.; Dossett, D.; Dovbnya, A.; Dupertuis, F.; Dzhelyadin, R.; Dziurda, A.; Dzyuba, A.; Easo, S.; Egede, U.; Egorychev, V.; Eidelman, S.; van Eijk, D.; Eisele, F.; Eisenhardt, S.; Ekelhof, R.; Eklund, L.; El Rifai, I.; Elsasser, Ch.; Elsby, D.; Esperante Pereira, D.; Falabella, A.; Färber, C.; Fardell, G.; Farinelli, C.; Farry, S.; Fave, V.; Fernandez Albor, V.; Ferreira Rodrigues, F.; Ferro-Luzzi, M.; Filippov, S.; Fitzpatrick, C.; Fontana, M.; Fontanelli, F.; Forty, R.; Francisco, O.; Frank, M.; Frei, C.; Frosini, M.; Furcas, S.; Gallas Torreira, A.; Galli, D.; Gandelman, M.; Gandini, P.; Gao, Y.; Garnier, J.-C.; Garofoli, J.; Garra Tico, J.; Garrido, L.; Gaspar, C.; Gauld, R.; Gersabeck, E.; Gersabeck, M.; Gershon, T.; Ghez, Ph.; Gibson, V.; Gligorov, V. V.; Göbel, C.; Golubkov, D.; Golutvin, A.; Gomes, A.; Gordon, H.; Grabalosa Gándara, M.; Graciani Diaz, R.; Granado Cardoso, L. A.; Graugés, E.; Graziani, G.; Grecu, A.; Greening, E.; Gregson, S.; Grünberg, O.; Gui, B.; Gushchin, E.; Guz, Yu.; Gys, T.; Hadjivasiliou, C.; Haefeli, G.; Haen, C.; Haines, S. C.; Hall, S.; Hampson, T.; Hansmann-Menzemer, S.; Harnew, N.; Harnew, S. T.; Harrison, J.; Harrison, P. F.; Hartmann, T.; He, J.; Heijne, V.; Hennessy, K.; Henrard, P.; Hernando Morata, J. A.; van Herwijnen, E.; Hicks, E.; Hill, D.; Hoballah, M.; Hopchev, P.; Hulsbergen, W.; Hunt, P.; Huse, T.; Hussain, N.; Huston, R. S.; Hutchcroft, D.; Hynds, D.; Iakovenko, V.; Ilten, P.; Imong, J.; Jacobsson, R.; Jaeger, A.; Jahjah Hussein, M.; Jans, E.; Jansen, F.; Jaton, P.; Jean-Marie, B.; Jing, F.; John, M.; Johnson, D.; Jones, C. R.; Jost, B.; Kaballo, M.; Kandybei, S.; Karacson, M.; Karbach, M.; Keaveney, J.; Kenyon, I. R.; Kerzel, U.; Ketel, T.; Keune, A.; Khanji, B.; Kim, Y. M.; Kochebina, O.; Komarov, I.; Komarov, V.; Koopman, R. F.; Koppenburg, P.; Korolev, M.; Kozlinskiy, A.; Kravchuk, L.; Kreplin, K.; Kreps, M.; Krocker, G.; Krokovny, P.; Kruse, F.; Kucharczyk, M.; Kudryavtsev, V.; Kvaratskheliya, T.; La Thi, V. N.; Lacarrere, D.; Lafferty, G.; Lai, A.; Lambert, D.; Lambert, R. W.; Lanciotti, E.; Lanfranchi, G.; Langenbruch, C.; Latham, T.; Lazzeroni, C.; Le Gac, R.; van Leerdam, J.; Lees, J.-P.; Lefèvre, R.; Leflat, A.; Lefrançois, J.; Leroy, O.; Lesiak, T.; Li, L.; Li, Y.; Li Gioi, L.; Liles, M.; Lindner, R.; Linn, C.; Liu, B.; Liu, G.; von Loeben, J.; Lopes, J. H.; Lopez Asamar, E.; Lopez-March, N.; Lu, H.; Luisier, J.; Mac Raighne, A.; Machefert, F.; Machikhiliyan, I. V.; Maciuc, F.; Maev, O.; Magnin, J.; Maino, M.; Malde, S.; Manca, G.; Mancinelli, G.; Mangiafave, N.; Marconi, U.; Märki, R.; Marks, J.; Martellotti, G.; Martens, A.; Martin, L.; Martín Sánchez, A.; Martinelli, M.; Martinez Santos, D.; Massafferri, A.; Mathe, Z.; Matteuzzi, C.; Matveev, M.; Maurice, E.; Mazurov, A.; McCarthy, J.; McGregor, G.; McNulty, R.; Meissner, M.; Merk, M.; Merkel, J.; Milanes, D. A.; Minard, M.-N.; Molina Rodriguez, J.; Monteil, S.; Moran, D.; Morawski, P.; Mountain, R.; Mous, I.; Muheim, F.; Müller, K.; Muresan, R.; Muryn, B.; Muster, B.; Mylroie-Smith, J.; Naik, P.; Nakada, T.; Nandakumar, R.; Nasteva, I.; Needham, M.; Neufeld, N.; Nguyen, A. D.; Nguyen-Mau, C.; Nicol, M.; Niess, V.; Nikitin, N.; Nikodem, T.; Nomerotski, A.; Novoselov, A.; Oblakowska-Mucha, A.; Obraztsov, V.; Oggero, S.; Ogilvy, S.; Okhrimenko, O.; Oldeman, R.; Orlandea, M.; Otalora Goicochea, J. M.; Owen, P.; Pal, B. K.; Palano, A.; Palutan, M.; Panman, J.; Papanestis, A.; Pappagallo, M.; Parkes, C.; Parkinson, C. J.; Passaleva, G.; Patel, G. D.; Patel, M.; Patrick, G. N.; Patrignani, C.; Pavel-Nicorescu, C.; Pazos Alvarez, A.; Pellegrino, A.; Penso, G.; Pepe Altarelli, M.; Perazzini, S.; Perego, D. L.; Perez Trigo, E.; Pérez-Calero Yzquierdo, A.; Perret, P.; Perrin-Terrin, M.; Pessina, G.; Petridis, K.; Petrolini, A.; Phan, A.; Picatoste Olloqui, E.; Pie Valls, B.; Pietrzyk, B.; Pilař, T.; Pinci, D.; Playfer, S.; Plo Casasus, M.; Polci, F.; Polok, G.; Poluektov, A.; Polycarpo, E.; Popov, D.; Popovici, B.; Potterat, C.; Powell, A.; Prisciandaro, J.; Pugatch, V.; Puig Navarro, A.; Qian, W.; Rademacker, J. H.; Rakotomiaramanana, B.; Rangel, M. S.; Raniuk, I.; Rauschmayr, N.; Raven, G.; Redford, S.; Reid, M. M.; dos Reis, A. C.; Ricciardi, S.; Richards, A.; Rinnert, K.; Rives Molina, V.; Roa Romero, D. A.; Robbe, P.; Rodrigues, E.; Rodriguez Perez, P.; Rogers, G. J.; Roiser, S.; Romanovsky, V.; Romero Vidal, A.; Rouvinet, J.; Ruf, T.; Ruiz, H.; Sabatino, G.; Saborido Silva, J. J.; Sagidova, N.; Sail, P.; Saitta, B.; Salzmann, C.; Sanmartin Sedes, B.; Sannino, M.; Santacesaria, R.; Santamarina Rios, C.; Santinelli, R.; Santovetti, E.; Sapunov, M.; Sarti, A.; Satriano, C.; Satta, A.; Savrie, M.; Savrina, D.; Schaack, P.; Schiller, M.; Schindler, H.; Schleich, S.; Schlupp, M.; Schmelling, M.; Schmidt, B.; Schneider, O.; Schopper, A.; Schune, M.-H.; Schwemmer, R.; Sciascia, B.; Sciubba, A.; Seco, M.; Semennikov, A.; Senderowska, K.; Sepp, I.; Serra, N.; Serrano, J.; Seyfert, P.; Shapkin, M.; Shapoval, I.; Shatalov, P.; Shcheglov, Y.; Shears, T.; Shekhtman, L.; Shevchenko, O.; Shevchenko, V.; Shires, A.; Silva Coutinho, R.; Skwarnicki, T.; Smith, N. A.; Smith, E.; Smith, M.; Sobczak, K.; Soler, F. J. P.; Solomin, A.; Soomro, F.; Souza, D.; Souza De Paula, B.; Spaan, B.; Sparkes, A.; Spradlin, P.; Stagni, F.; Stahl, S.; Steinkamp, O.; Stoica, S.; Stone, S.; Storaci, B.; Straticiuc, M.; Straumann, U.; Subbiah, V. K.; Swientek, S.; Szczekowski, M.; Szczypka, P.; Szumlak, T.; T'Jampens, S.; Teklishyn, M.; Teodorescu, E.; Teubert, F.; Thomas, C.; Thomas, E.; van Tilburg, J.; Tisserand, V.; Tobin, M.; Tolk, S.; Topp-Joergensen, S.; Torr, N.; Tournefier, E.; Tourneur, S.; Tran, M. T.; Tsaregorodtsev, A.; Tuning, N.; Ubeda Garcia, M.; Ukleja, A.; Urner, D.; Uwer, U.; Vagnoni, V.; Valenti, G.; Vazquez Gomez, R.; Vazquez Regueiro, P.; Vecchi, S.; Velthuis, J. J.; Veltri, M.; Veneziano, G.; Vesterinen, M.; Viaud, B.; Videau, I.; Vieira, D.; Vilasis-Cardona, X.; Visniakov, J.; Vollhardt, A.; Volyanskyy, D.; Voong, D.; Vorobyev, A.; Vorobyev, V.; Voss, H.; Voß, C.; Waldi, R.; Wallace, R.; Wandernoth, S.; Wang, J.; Ward, D. R.; Watson, N. K.; Webber, A. D.; Websdale, D.; Whitehead, M.; Wicht, J.; Wiedner, D.; Wiggers, L.; Wilkinson, G.; Williams, M. P.; Williams, M.; Wilson, F. F.; Wishahi, J.; Witek, M.; Witzeling, W.; Wotton, S. A.; Wright, S.; Wu, S.; Wyllie, K.; Xie, Y.; Xing, F.; Xing, Z.; Yang, Z.; Young, R.; Yuan, X.; Yushchenko, O.; Zangoli, M.; Zavertyaev, M.; Zhang, F.; Zhang, L.; Zhang, W. C.; Zhang, Y.; Zhelezov, A.; Zhong, L.; Zvyagin, A.

    2013-02-01

    First evidence of the B0→J/ψω decay is found and the Bs0→J/ψη and Bs0→J/ψη‧ decays are studied using a dataset corresponding to an integrated luminosity of 1.0 fb-1 collected by the LHCb experiment in proton-proton collisions at a centre-of-mass energy of s=7 TeV. The branching fractions of these decays are measured relative to that of the B0→J/ψρ0 decay:B(B0→J/ψω)B(B0→J/ψρ0)=0.89±0.19(stat)-0.13+0.07(syst), B(Bs0→J/ψη)B(B0→J/ψρ0)=14.0±1.2(stat)-1.5+1.1(syst)-1.0+1.1(fdfs), B(Bs0→J/ψη‧)B(B0→J/ψρ0)=12.7±1.1(stat)-1.3+0.5(syst)-0.9+1.0(fdfs), where the last uncertainty is due to the knowledge of fd/fs, the ratio of b-quark hadronization factors that accounts for the different production rate of B0 and Bs0 mesons. The ratio of the branching fractions of Bs0→J/ψη‧ and Bs0→J/ψη decays is measured to beB(Bs0→J/ψη‧)B(Bs0→J/ψη)=0.90±0.09(stat)-0.02+0.06(syst).

  7. Spectral properties near the Mott transition in the two-dimensional t-J model with next-nearest-neighbor hopping

    NASA Astrophysics Data System (ADS)

    Kohno, Masanori

    2018-05-01

    The single-particle spectral properties of the two-dimensional t-J model with next-nearest-neighbor hopping are investigated near the Mott transition by using cluster perturbation theory. The spectral features are interpreted by considering the effects of the next-nearest-neighbor hopping on the shift of the spectral-weight distribution of the two-dimensional t-J model. Various anomalous features observed in hole-doped and electron-doped high-temperature cuprate superconductors are collectively explained in the two-dimensional t-J model with next-nearest-neighbor hopping near the Mott transition.

  8. 76 FR 39156 - R. J. Corman Railroad Company/Bardstown Line-Lease and Operation Exemption-R. J. Corman Railroad...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-05

    ... DEPARTMENT OF TRANSPORTATION Surface Transportation Board [Docket No. FD 35364] R. J. Corman Railroad Company/Bardstown Line--Lease and Operation Exemption--R. J. Corman Railroad Property, LLC R. J... notice of exemption under 49 CFR 1150.41 to lease from R. J. Corman Railroad Property, LLC (RJC Railroad...

  9. The thymus of the hairless rhino-j (hr/hr-j) mice

    PubMed Central

    SAN JOSE, I.; GARCÍA-SUÁREZ, O.; HANNESTAD, J.; CABO, R.; GAUNA, L.; REPRESA, J.; VEGA, J. A.

    2001-01-01

    The hairless (hr) gene is expressed in a large number of tissues, primarily the skin, and a mutation in the hr gene is responsible for the typical cutaneous phenotype of hairless mice. Mutant hr mouse strains show immune defects involving especially T cells and macrophages, as well as an age-related immunodeficiency and an accelerated atrophy of the thymus. These data suggest that the hr mutation causes a defect of this organ, although hr transcripts have not been detected in fetal or adult mice thymus. The present study analyses the thymus of young (3 mo) and adult (9 mo) homozygous hr-rh-j mice (a strain of hairless mice) by means of structural techniques and immunohistochemistry to selectively identify thymic epithelial cells, dendritic cells, and macrophages. There were structural alterations in the thymus of both young and adult rh-rh-j mice, which were more severe in older animals. These alterations consisted of relative cortical atrophy, enlargement of blood vessels, proliferation of perivascular connective tissue, and the appearance of cysts. hr-rh-j mice also showed a decrease in the number of epithelial and dendritic cells, and macrophages. Taken together, present results strongly suggest degeneration and accelerated age-dependent regression of the thymus in hr-rh-j mice, which could explain at least in part the immune defects reported in hairless mouse strains. PMID:11327202

  10. Daniel J. Friedman | NREL

    Science.gov Websites

    solar cells for concentrator systems. One of his early focuses after joining the group was to adapt the J. Friedman Photo of Daniel J. Friedman. Daniel Friedman Group Research Manager III-Physics manager of the High Efficiency Crystalline Photovoltaics Group. He received his doctorate in applied

  11. Coherent and incoherent J /ψ photonuclear production in an energy-dependent hot-spot model

    NASA Astrophysics Data System (ADS)

    Cepila, J.; Contreras, J. G.; Krelina, M.

    2018-02-01

    In a previous publication, we have presented a model for the photoproduction of J /ψ vector mesons off protons, where the proton structure in the impact-parameter plane is described by an energy-dependent hot-spot profile. Here we extend this model to study the photonuclear production of J /ψ vector mesons in coherent and incoherent interactions of heavy nuclei. We study two methods to extend the model to the nuclear case: using the standard Glauber-Gribov formalism and using geometric scaling to obtain the nuclear saturation scale. We find that the incoherent cross section changes sizably with the inclusion of subnucleonic hot spots and that this change is energy dependent. We propose to search for this behavior by measuring the ratio of the incoherent to coherent cross sections at different energies. We compare the results of our model to results from the Relativistic Heavy-Ion Collider (RHIC) and from run 1 at the Large Hadron Collider (LHC), finding satisfactory agreement. We also present predictions for the LHC at the new energies reached in run 2. The predictions include J /ψ production in ultraperipheral collisions, as well as the recently observed photonuclear production in peripheral collisions.

  12. Study of J/ψ Production in Jets.

    PubMed

    Aaij, R; Adeva, B; Adinolfi, M; Ajaltouni, Z; Akar, S; Albrecht, J; Alessio, F; Alexander, M; Ali, S; Alkhazov, G; Alvarez Cartelle, P; Alves, A A; Amato, S; Amerio, S; Amhis, Y; An, L; Anderlini, L; Andreassi, G; Andreotti, M; Andrews, J E; Appleby, R B; Archilli, F; d'Argent, P; Arnau Romeu, J; Artamonov, A; Artuso, M; Aslanides, E; Auriemma, G; Baalouch, M; Babuschkin, I; Bachmann, S; Back, J J; Badalov, A; Baesso, C; Baker, S; Balagura, V; Baldini, W; Baranov, A; Barlow, R J; Barschel, C; Barsuk, S; Barter, W; Baryshnikov, F; Baszczyk, M; Batozskaya, V; Batsukh, B; Battista, V; Bay, A; Beaucourt, L; Beddow, J; Bedeschi, F; Bediaga, I; Beiter, A; Bel, L J; Bellee, V; Belloli, N; Belous, K; Belyaev, I; Ben-Haim, E; Bencivenni, G; Benson, S; Beranek, S; Berezhnoy, A; Bernet, R; Bertolin, A; Betancourt, C; Betti, F; Bettler, M-O; van Beuzekom, M; Bezshyiko, Ia; Bifani, S; Billoir, P; Bird, T; Birnkraut, A; Bitadze, A; Bizzeti, A; Blake, T; Blanc, F; Blouw, J; Blusk, S; Bocci, V; Boettcher, T; Bondar, A; Bondar, N; Bonivento, W; Bordyuzhin, I; Borgheresi, A; Borghi, S; Borisyak, M; Borsato, M; Bossu, F; Boubdir, M; Bowcock, T J V; Bowen, E; Bozzi, C; Braun, S; Britsch, M; Britton, T; Brodzicka, J; Buchanan, E; Burr, C; Bursche, A; Buytaert, J; Cadeddu, S; Calabrese, R; Calvi, M; Calvo Gomez, M; Camboni, A; Campana, P; Campora Perez, D H; Capriotti, L; Carbone, A; Carboni, G; Cardinale, R; Cardini, A; Carniti, P; Carson, L; Carvalho Akiba, K; Casse, G; Cassina, L; Castillo Garcia, L; Cattaneo, M; Cavallero, G; Cenci, R; Chamont, D; Charles, M; Charpentier, Ph; Chatzikonstantinidis, G; Chefdeville, M; Chen, S; Cheung, S-F; Chobanova, V; Chrzaszcz, M; Cid Vidal, X; Ciezarek, G; Clarke, P E L; Clemencic, M; Cliff, H V; Closier, J; Coco, V; Cogan, J; Cogneras, E; Cogoni, V; Cojocariu, L; Collazuol, G; Collins, P; Comerma-Montells, A; Contu, A; Cook, A; Coombs, G; Coquereau, S; Corti, G; Corvo, M; Costa Sobral, C M; Couturier, B; Cowan, G A; Craik, D C; Crocombe, A; Cruz Torres, M; Cunliffe, S; Currie, R; D'Ambrosio, C; Da Cunha Marinho, F; Dall'Occo, E; Dalseno, J; David, P N Y; Davis, A; De Bruyn, K; De Capua, S; De Cian, M; De Miranda, J M; De Paula, L; De Serio, M; De Simone, P; Dean, C T; Decamp, D; Deckenhoff, M; Del Buono, L; Demmer, M; Dendek, A; Derkach, D; Deschamps, O; Dettori, F; Dey, B; Di Canto, A; Dijkstra, H; Dordei, F; Dorigo, M; Dosil Suárez, A; Dovbnya, A; Dreimanis, K; Dufour, L; Dujany, G; Dungs, K; Durante, P; Dzhelyadin, R; Dziurda, A; Dzyuba, A; Déléage, N; Easo, S; Ebert, M; Egede, U; Egorychev, V; Eidelman, S; Eisenhardt, S; Eitschberger, U; Ekelhof, R; Eklund, L; Ely, S; Esen, S; Evans, H M; Evans, T; Falabella, A; Farley, N; Farry, S; Fay, R; Fazzini, D; Ferguson, D; Fernandez, G; Fernandez Prieto, A; Ferrari, F; Ferreira Rodrigues, F; Ferro-Luzzi, M; Filippov, S; Fini, R A; Fiore, M; Fiorini, M; Firlej, M; Fitzpatrick, C; Fiutowski, T; Fleuret, F; Fohl, K; Fontana, M; Fontanelli, F; Forshaw, D C; Forty, R; Franco Lima, V; Frank, M; Frei, C; Fu, J; Funk, W; Furfaro, E; Färber, C; Gallas Torreira, A; Galli, D; Gallorini, S; Gambetta, S; Gandelman, M; Gandini, P; Gao, Y; Garcia Martin, L M; García Pardiñas, J; Garra Tico, J; Garrido, L; Garsed, P J; Gascon, D; Gaspar, C; Gavardi, L; Gazzoni, G; Gerick, D; Gersabeck, E; Gersabeck, M; Gershon, T; Ghez, Ph; Gianì, S; Gibson, V; Girard, O G; Giubega, L; Gizdov, K; Gligorov, V V; Golubkov, D; Golutvin, A; Gomes, A; Gorelov, I V; Gotti, C; Govorkova, E; Graciani Diaz, R; Granado Cardoso, L A; Graugés, E; Graverini, E; Graziani, G; Grecu, A; Greim, R; Griffith, P; Grillo, L; Gruberg Cazon, B R; Grünberg, O; Gushchin, E; Guz, Yu; Gys, T; Göbel, C; Hadavizadeh, T; Hadjivasiliou, C; Haefeli, G; Haen, C; Haines, S C; Hamilton, B; Han, X; Hansmann-Menzemer, S; Harnew, N; Harnew, S T; Harrison, J; Hatch, M; He, J; Head, T; Heister, A; Hennessy, K; Henrard, P; Henry, L; van Herwijnen, E; Heß, M; Hicheur, A; Hill, D; Hombach, C; Hopchev, H; Hulsbergen, W; Humair, T; Hushchyn, M; Hutchcroft, D; Idzik, M; Ilten, P; Jacobsson, R; Jaeger, A; Jalocha, J; Jans, E; Jawahery, A; Jiang, F; John, M; Johnson, D; Jones, C R; Joram, C; Jost, B; Jurik, N; Kandybei, S; Karacson, M; Kariuki, J M; Karodia, S; Kecke, M; Kelsey, M; Kenzie, M; Ketel, T; Khairullin, E; Khanji, B; Khurewathanakul, C; Kirn, T; Klaver, S; Klimaszewski, K; Klimkovich, T; Koliiev, S; Kolpin, M; Komarov, I; Koppenburg, P; Kosmyntseva, A; Kozachuk, A; Kozeiha, M; Kravchuk, L; Kreplin, K; Kreps, M; Krokovny, P; Kruse, F; Krzemien, W; Kucewicz, W; Kucharczyk, M; Kudryavtsev, V; Kuonen, A K; Kurek, K; Kvaratskheliya, T; Lacarrere, D; Lafferty, G; Lai, A; Lanfranchi, G; Langenbruch, C; Latham, T; Lazzeroni, C; Le Gac, R; van Leerdam, J; Leflat, A; Lefrançois, J; Lefèvre, R; Lemaitre, F; Lemos Cid, E; Leroy, O; Lesiak, T; Leverington, B; Li, T; Li, Y; Likhomanenko, T; Lindner, R; Linn, C; Lionetto, F; Liu, X; Loh, D; Longstaff, I; Lopes, J H; Lucchesi, D; Lucio Martinez, M; Luo, H; Lupato, A; Luppi, E; Lupton, O; Lusiani, A; Lyu, X; Machefert, F; Maciuc, F; Maev, O; Maguire, K; Malde, S; Malinin, A; Maltsev, T; Manca, G; Mancinelli, G; Manning, P; Maratas, J; Marchand, J F; Marconi, U; Marin Benito, C; Marinangeli, M; Marino, P; Marks, J; Martellotti, G; Martin, M; Martinelli, M; Martinez Santos, D; Martinez Vidal, F; Martins Tostes, D; Massacrier, L M; Massafferri, A; Matev, R; Mathad, A; Mathe, Z; Matteuzzi, C; Mauri, A; Maurice, E; Maurin, B; Mazurov, A; McCann, M; McNab, A; McNulty, R; Meadows, B; Meier, F; Meissner, M; Melnychuk, D; Merk, M; Merli, A; Michielin, E; Milanes, D A; Minard, M-N; Mitzel, D S; Mogini, A; Molina Rodriguez, J; Monroy, I A; Monteil, S; Morandin, M; Morawski, P; Mordà, A; Morello, M J; Morgunova, O; Moron, J; Morris, A B; Mountain, R; Muheim, F; Mulder, M; Mussini, M; Müller, D; Müller, J; Müller, K; Müller, V; Naik, P; Nakada, T; Nandakumar, R; Nandi, A; Nasteva, I; Needham, M; Neri, N; Neubert, S; Neufeld, N; Neuner, M; Nguyen, T D; Nguyen-Mau, C; Nieswand, S; Niet, R; Nikitin, N; Nikodem, T; Nogay, A; Novoselov, A; O'Hanlon, D P; Oblakowska-Mucha, A; Obraztsov, V; Ogilvy, S; Okhrimenko, O; Oldeman, R; Onderwater, C J G; Otalora Goicochea, J M; Otto, A; Owen, P; Oyanguren, A; Pais, P R; Palano, A; Palutan, M; Papanestis, A; Pappagallo, M; Pappalardo, L L; Parker, W; Parkes, C; Passaleva, G; Pastore, A; Patel, G D; Patel, M; Patrignani, C; Pearce, A; Pellegrino, A; Penso, G; Pepe Altarelli, M; Perazzini, S; Perret, P; Pescatore, L; Petridis, K; Petrolini, A; Petrov, A; Petruzzo, M; Picatoste Olloqui, E; Pietrzyk, B; Pikies, M; Pinci, D; Pistone, A; Piucci, A; Placinta, V; Playfer, S; Plo Casasus, M; Poikela, T; Polci, F; Poluektov, A; Polyakov, I; Polycarpo, E; Pomery, G J; Ponce, S; Popov, A; Popov, D; Popovici, B; Poslavskii, S; Potterat, C; Price, E; Price, J D; Prisciandaro, J; Pritchard, A; Prouve, C; Pugatch, V; Puig Navarro, A; Punzi, G; Qian, W; Quagliani, R; Rachwal, B; Rademacker, J H; Rama, M; Ramos Pernas, M; Rangel, M S; Raniuk, I; Ratnikov, F; Raven, G; Redi, F; Reichert, S; Dos Reis, A C; Remon Alepuz, C; Renaudin, V; Ricciardi, S; Richards, S; Rihl, M; Rinnert, K; Rives Molina, V; Robbe, P; Rodrigues, A B; Rodrigues, E; Rodriguez Lopez, J A; Rodriguez Perez, P; Rogozhnikov, A; Roiser, S; Rollings, A; Romanovskiy, V; Romero Vidal, A; Ronayne, J W; Rotondo, M; Rudolph, M S; Ruf, T; Ruiz Valls, P; Saborido Silva, J J; Sadykhov, E; Sagidova, N; Saitta, B; Salustino Guimaraes, V; Sanchez Gonzalo, D; Sanchez Mayordomo, C; Sanmartin Sedes, B; Santacesaria, R; Santamarina Rios, C; Santimaria, M; Santovetti, E; Sarti, A; Satriano, C; Satta, A; Saunders, D M; Savrina, D; Schael, S; Schellenberg, M; Schiller, M; Schindler, H; Schlupp, M; Schmelling, M; Schmelzer, T; Schmidt, B; Schneider, O; Schopper, A; Schreiner, H F; Schubert, K; Schubiger, M; Schune, M-H; Schwemmer, R; Sciascia, B; Sciubba, A; Semennikov, A; Sergi, A; Serra, N; Serrano, J; Sestini, L; Seyfert, P; Shapkin, M; Shapoval, I; Shcheglov, Y; Shears, T; Shekhtman, L; Shevchenko, V; Siddi, B G; Silva Coutinho, R; Silva de Oliveira, L; Simi, G; Simone, S; Sirendi, M; Skidmore, N; Skwarnicki, T; Smith, E; Smith, I T; Smith, J; Smith, M; Soares Lavra, L; Sokoloff, M D; Soler, F J P; Souza De Paula, B; Spaan, B; Spradlin, P; Sridharan, S; Stagni, F; Stahl, M; Stahl, S; Stefko, P; Stefkova, S; Steinkamp, O; Stemmle, S; Stenyakin, O; Stevens, H; Stevenson, S; Stoica, S; Stone, S; Storaci, B; Stracka, S; Stramaglia, M E; Straticiuc, M; Straumann, U; Sun, L; Sutcliffe, W; Swientek, K; Syropoulos, V; Szczekowski, M; Szumlak, T; T'Jampens, S; Tayduganov, A; Tekampe, T; Tellarini, G; Teubert, F; Thomas, E; van Tilburg, J; Tilley, M J; Tisserand, V; Tobin, M; Tolk, S; Tomassetti, L; Tonelli, D; Topp-Joergensen, S; Toriello, F; Tournefier, E; Tourneur, S; Trabelsi, K; Traill, M; Tran, M T; Tresch, M; Trisovic, A; Tsaregorodtsev, A; Tsopelas, P; Tully, A; Tuning, N; Ukleja, A; Ustyuzhanin, A; Uwer, U; Vacca, C; Vagnoni, V; Valassi, A; Valat, S; Valenti, G; Vazquez Gomez, R; Vazquez Regueiro, P; Vecchi, S; van Veghel, M; Velthuis, J J; Veltri, M; Veneziano, G; Venkateswaran, A; Vernet, M; Vesterinen, M; Viana Barbosa, J V; Viaud, B; Vieira, D; Vieites Diaz, M; Viemann, H; Vilasis-Cardona, X; Vitti, M; Volkov, V; Vollhardt, A; Voneki, B; Vorobyev, A; Vorobyev, V; Voß, C; de Vries, J A; Vázquez Sierra, C; Waldi, R; Wallace, C; Wallace, R; Walsh, J; Wang, J; Ward, D R; Wark, H M; Watson, N K; Websdale, D; Weiden, A; Whitehead, M; Wicht, J; Wilkinson, G; Wilkinson, M; Williams, M; Williams, M P; Williams, M; Williams, T; Wilson, F F; Wimberley, J; Wishahi, J; Wislicki, W; Witek, M; Wormser, G; Wotton, S A; Wraight, K; Wyllie, K; Xie, Y; Xing, Z; Xu, Z; Yang, Z; Yao, Y; Yin, H; Yu, J; Yuan, X; Yushchenko, O; Zarebski, K A; Zavertyaev, M; Zhang, L; Zhang, Y; Zhang, Y; Zhelezov, A; Zheng, Y; Zhu, X; Zhukov, V; Zucchelli, S

    2017-05-12

    The production of J/ψ mesons in jets is studied in the forward region of proton-proton collisions using data collected with the LHCb detector at a center-of-mass energy of 13 TeV. The fraction of the jet transverse momentum carried by the J/ψ meson, z(J/ψ)≡p_{T}(J/ψ)/p_{T}(jet), is measured using jets with p_{T}(jet)>20  GeV in the pseudorapidity range 2.5<η(jet)<4.0. The observed z(J/ψ) distribution for J/ψ mesons produced in b-hadron decays is consistent with expectations. However, the results for prompt J/ψ production do not agree with predictions based on fixed-order nonrelativistic QCD. This is the first measurement of the p_{T} fraction carried by prompt J/ψ mesons in jets at any experiment.

  13. Pioneer 11 observations of trapped particle absorption by the Jovian ring and the satellites 1979, J1, J2, and J3

    NASA Technical Reports Server (NTRS)

    Pyle, K. R.; Mckibben, R. B.; Simpson, J. A.

    1983-01-01

    Pioneer 11 low energy telescope observation of charged particles around the Jovian satellites Amalthea, 1979 J1, J2, and J3, and the Jupiter ring are examined in the light of Voyager optical data from the same region. Good agreement was found in the absorption features of 0.5-8.7 MeV protons, electrons with energies of 3.4 MeV or more, and medium-Z nuclei. The heavier nuclei are suggested to be oxygen and sulfur particles with energies exceeding 70 MeV/nucleon. The observed intensity features in the regularly spaced radiation bands are interpreted as ring and satellite absorption.

  14. Models of the strongly lensed quasar DES J0408−5354

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Agnello, A.; et al.

    We present gravitational lens models of the multiply imaged quasar DES J0408-5354, recently discovered in the Dark Energy Survey (DES) footprint, with the aim of interpreting its remarkable quad-like configuration. We first model the DES single-epochmore » $grizY$ images as a superposition of a lens galaxy and four point-like objects, obtaining spectral energy distributions (SEDs) and relative positions for the objects. Three of the point sources (A,B,D) have SEDs compatible with the discovery quasar spectra, while the faintest point-like image (G2/C) shows significant reddening and a `grey' dimming of $$\\approx0.8$$mag. In order to understand the lens configuration, we fit different models to the relative positions of A,B,D. Models with just a single deflector predict a fourth image at the location of G2/C but considerably brighter and bluer. The addition of a small satellite galaxy ($$R_{\\rm E}\\approx0.2$$") in the lens plane near the position of G2/C suppresses the flux of the fourth image and can explain both the reddening and grey dimming. All models predict a main deflector with Einstein radius between $1.7"$ and $2.0",$ velocity dispersion $267-280$km/s and enclosed mass $$\\approx 6\\times10^{11}M_{\\odot},$$ even though higher resolution imaging data are needed to break residual degeneracies in model parameters. The longest time-delay (B-A) is estimated as $$\\approx 85$$ (resp. $$\\approx125$$) days by models with (resp. without) a perturber near G2/C. The configuration and predicted time-delays of J0408-5354 make it an excellent target for follow-up aimed at understanding the source quasar host galaxy and substructure in the lens, and measuring cosmological parameters. We also discuss some lessons learnt from J0408-5354 on lensed quasar finding strategies, due to its chromaticity and morphology.« less

  15. A radiative transfer module for calculating photolysis rates and solar heating in climate models: Solar-J v7.5

    NASA Astrophysics Data System (ADS)

    Hsu, Juno; Prather, Michael J.; Cameron-Smith, Philip; Veidenbaum, Alex; Nicolau, Alex

    2017-07-01

    Solar-J is a comprehensive radiative transfer model for the solar spectrum that addresses the needs of both solar heating and photochemistry in Earth system models. Solar-J is a spectral extension of Cloud-J, a standard in many chemical models that calculates photolysis rates in the 0.18-0.8 µm region. The Cloud-J core consists of an eight-stream scattering, plane-parallel radiative transfer solver with corrections for sphericity. Cloud-J uses cloud quadrature to accurately average over correlated cloud layers. It uses the scattering phase function of aerosols and clouds expanded to eighth order and thus avoids isotropic-equivalent approximations prevalent in most solar heating codes. The spectral extension from 0.8 to 12 µm enables calculation of both scattered and absorbed sunlight and thus aerosol direct radiative effects and heating rates throughout the Earth's atmosphere.The Solar-J extension adopts the correlated-k gas absorption bins, primarily water vapor, from the shortwave Rapid Radiative Transfer Model for general circulation model (GCM) applications (RRTMG-SW). Solar-J successfully matches RRTMG-SW's tropospheric heating profile in a clear-sky, aerosol-free, tropical atmosphere. We compare both codes in cloudy atmospheres with a liquid-water stratus cloud and an ice-crystal cirrus cloud. For the stratus cloud, both models use the same physical properties, and we find a systematic low bias of about 3 % in planetary albedo across all solar zenith angles caused by RRTMG-SW's two-stream scattering. Discrepancies with the cirrus cloud using any of RRTMG-SW's three different parameterizations are as large as about 20-40 % depending on the solar zenith angles and occur throughout the atmosphere.Effectively, Solar-J has combined the best components of RRTMG-SW and Cloud-J to build a high-fidelity module for the scattering and absorption of sunlight in the Earth's atmosphere, for which the three major components - wavelength integration, scattering, and

  16. J-Plus Web Portal

    NASA Astrophysics Data System (ADS)

    Civera Lorenzo, Tamara

    2017-10-01

    Brief presentation about the J-PLUS EDR data access web portal (http://archive.cefca.es/catalogues/jplus-edr) where the different services available to retrieve images and catalogues data have been presented.J-PLUS Early Data Release (EDR) archive includes two types of data: images and dual and single catalogue data which include parameters measured from images. J-PLUS web portal offers catalogue data and images through several different online data access tools or services each suited to a particular need. The different services offered are: Coverage map Sky navigator Object visualization Image search Cone search Object list search Virtual observatory services: Simple Cone Search Simple Image Access Protocol Simple Spectral Access Protocol Table Access Protocol

  17. Timothy J. Coutts | NREL

    Science.gov Websites

    conducting films of cadmium stannate: X. Wu, and T. J. Coutts (NREL IR#9545) PV devices comprising cadmium (NREL IR#9535) PV devices comprising zinc stannate buffer layer and method for making: X. Wu, P. Sheldon , and T. J. Coutts (NREL IR#9721) (filed) Publications View all NREL publications for Dr. Coutts. Awards

  18. SimPackJ/S: a web-oriented toolkit for discrete event simulation

    NASA Astrophysics Data System (ADS)

    Park, Minho; Fishwick, Paul A.

    2002-07-01

    SimPackJ/S is the JavaScript and Java version of SimPack, which means SimPackJ/S is a collection of JavaScript and Java libraries and executable programs for computer simulations. The main purpose of creating SimPackJ/S is that we allow existing SimPack users to expand simulation areas and provide future users with a freeware simulation toolkit to simulate and model a system in web environments. One of the goals for this paper is to introduce SimPackJ/S. The other goal is to propose translation rules for converting C to JavaScript and Java. Most parts demonstrate the translation rules with examples. In addition, we discuss a 3D dynamic system model and overview an approach to 3D dynamic systems using SimPackJ/S. We explain an interface between SimPackJ/S and the 3D language--Virtual Reality Modeling Language (VRML). This paper documents how to translate C to JavaScript and Java and how to utilize SimPackJ/S within a 3D web environment.

  19. Mid-J CO Shock Tracing Observations of Infrared Dark Clouds. III. SLED Fitting

    NASA Astrophysics Data System (ADS)

    Pon, A.; Kaufman, M. J.; Johnstone, D.; Caselli, P.; Fontani, F.; Butler, M. J.; Jiménez-Serra, I.; Palau, A.; Tan, J. C.

    2016-08-01

    Giant molecular clouds contain supersonic turbulence that can locally heat small fractions of gas to over 100 K. We run shock models for low-velocity, C-type shocks propagating into gas with densities between 103 and 105 cm-3 and find that CO lines are the most important cooling lines. Comparison to photodissociation region (PDR) models indicates that mid-J CO lines (J = 8 \\to 7 and higher) should be dominated by emission from shocked gas. In Papers I and II we presented CO J = 3 \\to 2, 8 \\to 7, and 9 \\to 8 observations toward four primarily quiescent clumps within infrared dark clouds. Here we fit PDR models to the combined spectral line energy distributions and show that the PDR models that best fit the low-J CO emission underpredict the mid-J CO emission by orders of magnitude, strongly hinting at a hot gas component within these clumps. The low-J CO data clearly show that the integrated intensities of both the CO J = 8 \\to 7 and 9 \\to 8 lines are anomalously high, such that the line ratio can be used to characterize the hot gas component. Shock models are reasonably consistent with the observed mid-J CO emission, with models with densities near {10}4.5 cm-3 providing the best agreement. Where this mid-J CO is detected, the mean volume filling factor of the hot gas is 0.1%. Much of the observed mid-J CO emission, however, is also associated with known protostars and may be due to protostellar feedback.

  20. Pea chloroplast DnaJ-J8 and Toc12 are encoded by the same gene and localized in the stroma.

    PubMed

    Chiu, Chi-Chou; Chen, Lih-Jen; Li, Hsou-min

    2010-11-01

    Toc12 is a novel J domain-containing protein identified in pea (Pisum sativum) chloroplasts. It was shown to be an integral outer membrane protein localizing in the intermembrane space of the chloroplast envelope. Furthermore, Toc12 was shown to associate with an intermembrane space Hsp70, suggesting that Toc12 is important for protein translocation across the chloroplast envelope. Toc12 shares a high degree of sequence similarity with Arabidopsis (Arabidopsis thaliana) DnaJ-J8, which has been suggested to be a soluble protein of the chloroplast stroma. Here, we isolated genes encoding DnaJ-J8 from pea and found that Toc12 is a truncated clone of one of the pea DnaJ-J8s. Protein import analyses indicate that Toc12 and DnaJ-J8s possess a cleavable transit peptide and are localized in the stroma. Arabidopsis mutants with T-DNA insertions in the DnaJ-J8 gene show no defect in chloroplast protein import. Implications of these results in the energetics and mechanisms of chloroplast protein import are discussed.

  1. XTE J1946+274 = GRO J1944+26 Observations with RXTE and BATSE

    NASA Technical Reports Server (NTRS)

    Wilson, Colleen A.; Finger, Mark H.; Scott, D. Matthew

    2000-01-01

    XTE J1946+274 = GRO J1944+26 is a 15.8 second transient X-ray pulsar discovered simultaneously with the Rossi X-ray Timing Explorer (RXTE) and Burst and Transient Source Experiment (BATSE) onboard the Compton Gamma Ray Observatory (CGRO) during an outburst in September 1998. Since its discovery, XTE J1946+274 has undergone 7 regularly spaced outbursts, that were observed with BATSE and the RXTE All-Sky Monitor (ASM). The pulse frequency and pulsed flux measurements with BATSE suggest that XTE J1946+274 is in an about 170 day orbit and is outbursting twice per orbit. The first outburst, which was brighter and longer than subsequent outbursts, was also observed with the RXTE Proportional Counter Array (PCA). We present histories of pulse frequency, pulsed flux, and total flux measured in the 20-50 keV band with BATSE and a history of the 2-10 keV total flux measured with the RXTE ASM. From the first outburst, we present energy and power spectra and pulse profiles from RXTE PCA observations.

  2. Theoretical study of homonuclear J coupling between quadrupolar spins: single-crystal, DOR, and J-resolved NMR.

    PubMed

    Perras, Frédéric A; Bryce, David L

    2014-05-01

    The theory describing homonuclear indirect nuclear spin-spin coupling (J) interactions between pairs of quadrupolar nuclei is outlined and supported by numerical calculations. The expected first-order multiplets for pairs of magnetically equivalent (A2), chemically equivalent (AA'), and non-equivalent (AX) quadrupolar nuclei are given. The various spectral changeovers from one first-order multiplet to another are investigated with numerical simulations using the SIMPSON program and the various thresholds defining each situation are given. The effects of chemical equivalence, as well as quadrupolar coupling, chemical shift differences, and dipolar coupling on double-rotation (DOR) and J-resolved NMR experiments for measuring homonuclear J coupling constants are investigated. The simulated J coupling multiplets under DOR conditions largely resemble the ideal multiplets predicted for single crystals, and a characteristic multiplet is expected for each of the A2, AA', and AX cases. The simulations demonstrate that it should be straightforward to distinguish between magnetic inequivalence and equivalence using J-resolved NMR, as was speculated previously. Additionally, it is shown that the second-order quadrupolar-dipolar cross-term does not affect the splittings in J-resolved experiments. Overall, the homonuclear J-resolved experiment for half-integer quadrupolar nuclei is demonstrated to be robust with respect to the effects of first- and second-order quadrupolar coupling, dipolar coupling, and chemical shift differences. Copyright © 2014 Elsevier Inc. All rights reserved.

  3. Similarity of PSR J1906+0746 TO PSR J0737-3039: A Candidate of a New Double Pulsar System?

    NASA Astrophysics Data System (ADS)

    Yang, Yi-Yan; Zhang, Cheng-Min; Li, Di; Wang, De-Hua; Pan, Yuan-Yue; Lingfu, Rong-Feng; Zhou, Zhu-Wen

    2017-02-01

    PSR J1906+0746 is a nonrecycled strong magnetic field neutron star (NS), sharing the properties of the secondary-formed NS PSR J0737-3039B in the double pulsar system PSR J0737-3039AB. By comparing the orbital parameters of PSR J1906+0746 with those of PSR J0737-3039AB, we conclude that both systems have a similar origin and evolution history, involving an e-capture process for forming the second-born NS, like in the case of PSR J0737-3039B. We expect the companion of PSR J1906+0746 to be a long-lived recycled pulsar with radio beams that currently cannot be observed from Earth. We suggest possible ways to detect its presence. To compare PSR J1906+0746 with PSR J0737-3039, we also present the mass distribution of eight pairs of double NSs and find that in double NSs the mass of the recycled pulsar is usually larger than that of the nonrecycled one, which may be the result of accretion.

  4. Development of the Non-Hydrostatic Jupiter Global Ionosphere Thermosphere Model (J-GITM): Status and Current Simulations

    NASA Astrophysics Data System (ADS)

    Bougher, Stephen; Ridley, Aaron; Majeed, Tariq; Waite, J. Hunter; Gladstone, Randy; Bell, Jared

    2016-07-01

    The primary objectives for development and validation of a new 3-D non-hydrostatic model of Jupiter's upper atmosphere is to improve our understanding of Jupiter's thermosphere-ionosphere-magnetosphere system and to provide a global context within which to analyze the data retrieved from the new JUNO mission. The new J-GITM model presently incorporates the progress made on the previous Jupiter-TGCM code (i.e. key parameterizations, ion-neutral chemistry, IR cooling) while also employing the non-hydrostatic numerical core of the Earth Global Ionosphere-Thermosphere Model (GITM). The GITM numerical framework has been successfully applied to Earth, Mars, and Titan (see Ridley et al. [2006], Bougher et al. [2015], Bell [2008, 2010]). Moreover, it has been shown to simulate the effects of strong, localized heat sources (such as joule heating and auroral heating) more accurately than strictly hydrostatic GCMs (Deng et al. [2007, 2008]). Thus far, in the J-GITM model development and testing, model capability has been progressively augmented to capture the neutral composition (e.g. H, H2, He major species), 3-component neutral winds, and thermal structure, as well as the ion composition (H3+, H2+, and H+ among others) above 250 km. Presently, J-GITM: (a) provides an interactive calculation for auroral particle precipitation (i.e. heating, ionization), an improvement over the static formulation used previously in the J-TGCM (Bougher et al., 2005; Majeed et al., 2005, 2009, 2015); (b) self-consistently calculates an ionosphere using updated ion-neutral chemistry, ion dynamics, and electron transport; (c) simulates the chemistry that forms key hydrocarbons at the base of the thermosphere, focusing on CH4, C2H2, and C2H6; (d) allows the production of H3+, CH4, C2H2, and C2H6 to modify the global thermal balance of Jupiter through their non-LTE radiative cooling; (e) provides a calculation of H2 vibrational chemistry to regulate H+ densities; and (f) uses the improved

  5. J-2X engine

    NASA Image and Video Library

    2012-04-20

    NASA Administrator Charles Bolden (r) takes an up-close look at the first development J-2X rocket engine on the A-2 Test Stand at Stennis Space Center during an April 20, 2012, visit. Pictured with Bolden is A-2 Test Stand Director Skip Roberts. The J-2X engine is being developed for NASA by Pratt & Whitney Rocketdyne.

  6. J-2X engine

    NASA Image and Video Library

    2012-04-20

    NASA Administrator Charles Bolden (r) takes an up-close look at the first development J-2X rocket engine on the A-2 Test Stand at Stennis Space Center during an April 20, 2012, visit. Pictured with Bolden is A-2 Test Stand Director Skip Roberts. The J-2X engine i s being developed for NASA by Pratt & Whitney Rocketdyne.

  7. Unified molecular field theory for collinear and noncollinear Heisenberg antiferromagnets

    DOE PAGES

    Johnston, David C.

    2015-02-27

    In this study, a unified molecular field theory (MFT) is presented that applies to both collinear and planar noncollinear Heisenberg antiferromagnets (AFs) on the same footing. The spins in the system are assumed to be identical and crystallographically equivalent. This formulation allows calculations of the anisotropic magnetic susceptibility χ versus temperature T below the AF ordering temperature T N to be carried out for arbitrary Heisenberg exchange interactions J ij between arbitrary neighbors j of a given spin i without recourse to magnetic sublattices. The Weiss temperature θ p in the Curie-Weiss law is written in terms of the Jmore » ij values and T N in terms of the J ij values and an assumed AF structure. Other magnetic and thermal properties are then expressed in terms of quantities easily accessible from experiment as laws of corresponding states for a given spin S. For collinear ordering these properties are the reduced temperature t=T/T N, the ratio f = θ p/T N, and S. For planar noncollinear helical or cycloidal ordering, an additional parameter is the wave vector of the helix or cycloid. The MFT is also applicable to AFs with other AF structures. The MFT predicts that χ(T ≤ T N) of noncollinear 120° spin structures on triangular lattices is isotropic and independent of S and T and thus clarifies the origin of this universally observed behavior. The high-field magnetization and heat capacity for fields applied perpendicular to the ordering axis (collinear AFs) and ordering plane (planar noncollinear AFs) are also calculated and expressed for both types of AF structures as laws of corresponding states for a given S, and the reduced perpendicular field versus reduced temperature phase diagram is constructed.« less

  8. Measurement of the Ratio of Branching Fractions B (Bc+→J /ψ τ+ντ)/B (Bc+→J /ψ μ+νμ)

    NASA Astrophysics Data System (ADS)

    Aaij, R.; Adeva, B.; Adinolfi, M.; Ajaltouni, Z.; Akar, S.; Albrecht, J.; Alessio, F.; Alexander, M.; Alfonso Albero, A.; Ali, S.; Alkhazov, G.; Alvarez Cartelle, P.; Alves, A. A.; Amato, S.; Amerio, S.; Amhis, Y.; An, L.; Anderlini, L.; Andreassi, G.; Andreotti, M.; Andrews, J. E.; Appleby, R. B.; Archilli, F.; d'Argent, P.; Arnau Romeu, J.; Artamonov, A.; Artuso, M.; Aslanides, E.; Atzeni, M.; Auriemma, G.; Baalouch, M.; Babuschkin, I.; Bachmann, S.; Back, J. J.; Badalov, A.; Baesso, C.; Baker, S.; Balagura, V.; Baldini, W.; Baranov, A.; Barlow, R. J.; Barschel, C.; Barsuk, S.; Barter, W.; Baryshnikov, F.; Batozskaya, V.; Battista, V.; Bay, A.; Beaucourt, L.; Beddow, J.; Bedeschi, F.; Bediaga, I.; Beiter, A.; Bel, L. J.; Beliy, N.; Bellee, V.; Belloli, N.; Belous, K.; Belyaev, I.; Ben-Haim, E.; Bencivenni, G.; Benson, S.; Beranek, S.; Berezhnoy, A.; Bernet, R.; Berninghoff, D.; Bertholet, E.; Bertolin, A.; Betancourt, C.; Betti, F.; Bettler, M.-O.; van Beuzekom, M.; Bezshyiko, Ia.; Bifani, S.; Billoir, P.; Birnkraut, A.; Bizzeti, A.; Bjørn, M.; Blake, T.; Blanc, F.; Blusk, S.; Bocci, V.; Boettcher, T.; Bondar, A.; Bondar, N.; Bordyuzhin, I.; Borghi, S.; Borisyak, M.; Borsato, M.; Bossu, F.; Boubdir, M.; Bowcock, T. J. V.; Bowen, E.; Bozzi, C.; Braun, S.; Britton, T.; Brodzicka, J.; Brundu, D.; Buchanan, E.; Burr, C.; Bursche, A.; Buytaert, J.; Byczynski, W.; Cadeddu, S.; Cai, H.; Calabrese, R.; Calladine, R.; Calvi, M.; Calvo Gomez, M.; Camboni, A.; Campana, P.; Campora Perez, D. H.; Capriotti, L.; Carbone, A.; Carboni, G.; Cardinale, R.; Cardini, A.; Carniti, P.; Carson, L.; Carvalho Akiba, K.; Casse, G.; Cassina, L.; Cattaneo, M.; Cavallero, G.; Cenci, R.; Chamont, D.; Chapman, M. G.; Charles, M.; Charpentier, Ph.; Chatzikonstantinidis, G.; Chefdeville, M.; Chen, S.; Cheung, S. F.; Chitic, S.-G.; Chobanova, V.; Chrzaszcz, M.; Chubykin, A.; Ciambrone, P.; Cid Vidal, X.; Ciezarek, G.; Clarke, P. E. L.; Clemencic, M.; Cliff, H. V.; Closier, J.; Cogan, J.; Cogneras, E.; Cogoni, V.; Cojocariu, L.; Collins, P.; Colombo, T.; Comerma-Montells, A.; Contu, A.; Cook, A.; Coombs, G.; Coquereau, S.; Corti, G.; Corvo, M.; Costa Sobral, C. M.; Couturier, B.; Cowan, G. A.; Craik, D. C.; Crocombe, A.; Cruz Torres, M.; Currie, R.; D'Ambrosio, C.; Da Cunha Marinho, F.; Dall'Occo, E.; Dalseno, J.; Davis, A.; De Aguiar Francisco, O.; De Bruyn, K.; De Capua, S.; De Cian, M.; De Miranda, J. M.; De Paula, L.; De Serio, M.; De Simone, P.; Dean, C. T.; Decamp, D.; Del Buono, L.; Dembinski, H.-P.; Demmer, M.; Dendek, A.; Derkach, D.; Deschamps, O.; Dettori, F.; Dey, B.; Di Canto, A.; Di Nezza, P.; Dijkstra, H.; Dordei, F.; Dorigo, M.; Dosil Suárez, A.; Douglas, L.; Dovbnya, A.; Dreimanis, K.; Dufour, L.; Dujany, G.; Durante, P.; Dzhelyadin, R.; Dziewiecki, M.; Dziurda, A.; Dzyuba, A.; Easo, S.; Ebert, M.; Egede, U.; Egorychev, V.; Eidelman, S.; Eisenhardt, S.; Eitschberger, U.; Ekelhof, R.; Eklund, L.; Ely, S.; Esen, S.; Evans, H. M.; Evans, T.; Falabella, A.; Farley, N.; Farry, S.; Fazzini, D.; Federici, L.; Ferguson, D.; Fernandez, G.; Fernandez Declara, P.; Fernandez Prieto, A.; Ferrari, F.; Ferreira Rodrigues, F.; Ferro-Luzzi, M.; Filippov, S.; Fini, R. A.; Fiorini, M.; Firlej, M.; Fitzpatrick, C.; Fiutowski, T.; Fleuret, F.; Fohl, K.; Fontana, M.; Fontanelli, F.; Forshaw, D. C.; Forty, R.; Franco Lima, V.; Frank, M.; Frei, C.; Fu, J.; Funk, W.; Furfaro, E.; Färber, C.; Gabriel, E.; Gallas Torreira, A.; Galli, D.; Gallorini, S.; Gambetta, S.; Gandelman, M.; Gandini, P.; Gao, Y.; Garcia Martin, L. M.; García Pardiñas, J.; Garra Tico, J.; Garrido, L.; Garsed, P. J.; Gascon, D.; Gaspar, C.; Gavardi, L.; Gazzoni, G.; Gerick, D.; Gersabeck, E.; Gersabeck, M.; Gershon, T.; Ghez, Ph.; Gianı, S.; Gibson, V.; Girard, O. G.; Giubega, L.; Gizdov, K.; Gligorov, V. V.; Golubkov, D.; Golutvin, A.; Gomes, A.; Gorelov, I. V.; Gotti, C.; Govorkova, E.; Grabowski, J. P.; Graciani Diaz, R.; Granado Cardoso, L. A.; Graugés, E.; Graverini, E.; Graziani, G.; Grecu, A.; Greim, R.; Griffith, P.; Grillo, L.; Gruber, L.; Gruberg Cazon, B. R.; Grünberg, O.; Gushchin, E.; Guz, Yu.; Gys, T.; Göbel, C.; Hadavizadeh, T.; Hadjivasiliou, C.; Haefeli, G.; Haen, C.; Haines, S. C.; Hamilton, B.; Han, X.; Hancock, T. H.; Hansmann-Menzemer, S.; Harnew, N.; Harnew, S. T.; Hasse, C.; Hatch, M.; He, J.; Hecker, M.; Heinicke, K.; Heister, A.; Hennessy, K.; Henrard, P.; Henry, L.; van Herwijnen, E.; Heß, M.; Hicheur, A.; Hill, D.; Hombach, C.; Hopchev, P. H.; Hu, W.; Huard, Z. C.; Hulsbergen, W.; Humair, T.; Hushchyn, M.; Hutchcroft, D.; Ibis, P.; Idzik, M.; Ilten, P.; Jacobsson, R.; Jalocha, J.; Jans, E.; Jawahery, A.; Jiang, F.; John, M.; Johnson, D.; Jones, C. R.; Joram, C.; Jost, B.; Jurik, N.; Kandybei, S.; Karacson, M.; Kariuki, J. M.; Karodia, S.; Kazeev, N.; Kecke, M.; Keizer, F.; Kelsey, M.; Kenzie, M.; Ketel, T.; Khairullin, E.; Khanji, B.; Khurewathanakul, C.; Kirn, T.; Klaver, S.; Klimaszewski, K.; Klimkovich, T.; Koliiev, S.; Kolpin, M.; Kopecna, R.; Koppenburg, P.; Kosmyntseva, A.; Kotriakhova, S.; Kozeiha, M.; Kravchuk, L.; Kreps, M.; Kress, F.; Krokovny, P.; Kruse, F.; Krzemien, W.; Kucewicz, W.; Kucharczyk, M.; Kudryavtsev, V.; Kuonen, A. K.; Kvaratskheliya, T.; Lacarrere, D.; Lafferty, G.; Lai, A.; Lanfranchi, G.; Langenbruch, C.; Latham, T.; Lazzeroni, C.; Le Gac, R.; Leflat, A.; Lefrançois, J.; Lefèvre, R.; Lemaitre, F.; Lemos Cid, E.; Leroy, O.; Lesiak, T.; Leverington, B.; Li, P.-R.; Li, T.; Li, Y.; Li, Z.; Likhomanenko, T.; Lindner, R.; Lionetto, F.; Lisovskyi, V.; Liu, X.; Loh, D.; Loi, A.; Longstaff, I.; Lopes, J. H.; Lucchesi, D.; Lucio Martinez, M.; Luo, H.; Lupato, A.; Luppi, E.; Lupton, O.; Lusiani, A.; Lyu, X.; Machefert, F.; Maciuc, F.; Macko, V.; Mackowiak, P.; Maddrell-Mander, S.; Maev, O.; Maguire, K.; Maisuzenko, D.; Majewski, M. W.; Malde, S.; Malecki, B.; Malinin, A.; Maltsev, T.; Manca, G.; Mancinelli, G.; Marangotto, D.; Maratas, J.; Marchand, J. F.; Marconi, U.; Marin Benito, C.; Marinangeli, M.; Marino, P.; Marks, J.; Martellotti, G.; Martin, M.; Martinelli, M.; Martinez Santos, D.; Martinez Vidal, F.; Massacrier, L. M.; Massafferri, A.; Matev, R.; Mathad, A.; Mathe, Z.; Matteuzzi, C.; Mauri, A.; Maurice, E.; Maurin, B.; Mazurov, A.; McCann, M.; McNab, A.; McNulty, R.; Mead, J. V.; Meadows, B.; Meaux, C.; Meier, F.; Meinert, N.; Melnychuk, D.; Merk, M.; Merli, A.; Michielin, E.; Milanes, D. A.; Millard, E.; Minard, M.-N.; Minzoni, L.; Mitzel, D. S.; Mogini, A.; Molina Rodriguez, J.; Mombächer, T.; Monroy, I. A.; Monteil, S.; Morandin, M.; Morello, M. J.; Morgunova, O.; Moron, J.; Morris, A. B.; Mountain, R.; Muheim, F.; Mulder, M.; Müller, D.; Müller, J.; Müller, K.; Müller, V.; Naik, P.; Nakada, T.; Nandakumar, R.; Nandi, A.; Nasteva, I.; Needham, M.; Neri, N.; Neubert, S.; Neufeld, N.; Neuner, M.; Nguyen, T. D.; Nguyen-Mau, C.; Nieswand, S.; Niet, R.; Nikitin, N.; Nikodem, T.; Nogay, A.; O'Hanlon, D. P.; Oblakowska-Mucha, A.; Obraztsov, V.; Ogilvy, S.; Oldeman, R.; Onderwater, C. J. G.; Ossowska, A.; Otalora Goicochea, J. M.; Owen, P.; Oyanguren, A.; Pais, P. R.; Palano, A.; Palutan, M.; Papanestis, A.; Pappagallo, M.; Pappalardo, L. L.; Parker, W.; Parkes, C.; Passaleva, G.; Pastore, A.; Patel, M.; Patrignani, C.; Pearce, A.; Pellegrino, A.; Penso, G.; Pepe Altarelli, M.; Perazzini, S.; Perret, P.; Pescatore, L.; Petridis, K.; Petrolini, A.; Petrov, A.; Petruzzo, M.; Picatoste Olloqui, E.; Pietrzyk, B.; Pikies, M.; Pinci, D.; Pisani, F.; Pistone, A.; Piucci, A.; Placinta, V.; Playfer, S.; Plo Casasus, M.; Polci, F.; Poli Lener, M.; Poluektov, A.; Polyakov, I.; Polycarpo, E.; Pomery, G. J.; Ponce, S.; Popov, A.; Popov, D.; Poslavskii, S.; Potterat, C.; Price, E.; Prisciandaro, J.; Prouve, C.; Pugatch, V.; Puig Navarro, A.; Pullen, H.; Punzi, G.; Qian, W.; Quagliani, R.; Quintana, B.; Rachwal, B.; Rademacker, J. H.; Rama, M.; Ramos Pernas, M.; Rangel, M. S.; Raniuk, I.; Ratnikov, F.; Raven, G.; Ravonel Salzgeber, M.; Reboud, M.; Redi, F.; Reichert, S.; dos Reis, A. C.; Remon Alepuz, C.; Renaudin, V.; Ricciardi, S.; Richards, S.; Rihl, M.; Rinnert, K.; Rives Molina, V.; Robbe, P.; Robert, A.; Rodrigues, A. B.; Rodrigues, E.; Rodriguez Lopez, J. A.; Rogozhnikov, A.; Roiser, S.; Rollings, A.; Romanovskiy, V.; Romero Vidal, A.; Ronayne, J. W.; Rotondo, M.; Rudolph, M. S.; Ruf, T.; Ruiz Valls, P.; Ruiz Vidal, J.; Saborido Silva, J. J.; Sadykhov, E.; Sagidova, N.; Saitta, B.; Salustino Guimaraes, V.; Sanchez Mayordomo, C.; Sanmartin Sedes, B.; Santacesaria, R.; Santamarina Rios, C.; Santimaria, M.; Santovetti, E.; Sarpis, G.; Sarti, A.; Satriano, C.; Satta, A.; Saunders, D. M.; Savrina, D.; Schael, S.; Schellenberg, M.; Schiller, M.; Schindler, H.; Schmelling, M.; Schmelzer, T.; Schmidt, B.; Schneider, O.; Schopper, A.; Schreiner, H. F.; Schubiger, M.; Schune, M.-H.; Schwemmer, R.; Sciascia, B.; Sciubba, A.; Semennikov, A.; Sepulveda, E. S.; Sergi, A.; Serra, N.; Serrano, J.; Sestini, L.; Seyfert, P.; Shapkin, M.; Shapoval, I.; Shcheglov, Y.; Shears, T.; Shekhtman, L.; Shevchenko, V.; Siddi, B. G.; Silva Coutinho, R.; Silva de Oliveira, L.; Simi, G.; Simone, S.; Sirendi, M.; Skidmore, N.; Skwarnicki, T.; Smith, E.; Smith, I. T.; Smith, J.; Smith, M.; Soares Lavra, l.; Sokoloff, M. D.; Soler, F. J. P.; Souza De Paula, B.; Spaan, B.; Spradlin, P.; Sridharan, S.; Stagni, F.; Stahl, M.; Stahl, S.; Stefko, P.; Stefkova, S.; Steinkamp, O.; Stemmle, S.; Stenyakin, O.; Stepanova, M.; Stevens, H.; Stone, S.; Storaci, B.; Stracka, S.; Stramaglia, M. E.; Straticiuc, M.; Straumann, U.; Sun, J.; Sun, L.; Sutcliffe, W.; Swientek, K.; Syropoulos, V.; Szumlak, T.; Szymanski, M.; T'Jampens, S.; Tayduganov, A.; Tekampe, T.; Tellarini, G.; Teubert, F.; Thomas, E.; van Tilburg, J.; Tilley, M. J.; Tisserand, V.; Tobin, M.; Tolk, S.; Tomassetti, L.; Tonelli, D.; Toriello, F.; Tourinho Jadallah Aoude, R.; Tournefier, E.; Traill, M.; Tran, M. T.; Tresch, M.; Trisovic, A.; Tsaregorodtsev, A.; Tsopelas, P.; Tully, A.; Tuning, N.; Ukleja, A.; Usachov, A.; Ustyuzhanin, A.; Uwer, U.; Vacca, C.; Vagner, A.; Vagnoni, V.; Valassi, A.; Valat, S.; Valenti, G.; Vazquez Gomez, R.; Vazquez Regueiro, P.; Vecchi, S.; van Veghel, M.; Velthuis, J. J.; Veltri, M.; Veneziano, G.; Venkateswaran, A.; Verlage, T. A.; Vernet, M.; Vesterinen, M.; Viana Barbosa, J. V.; Viaud, B.; Vieira, D.; Vieites Diaz, M.; Viemann, H.; Vilasis-Cardona, X.; Vitti, M.; Volkov, V.; Vollhardt, A.; Voneki, B.; Vorobyev, A.; Vorobyev, V.; Voß, C.; de Vries, J. A.; Vázquez Sierra, C.; Waldi, R.; Wallace, C.; Wallace, R.; Walsh, J.; Wang, J.; Ward, D. R.; Wark, H. M.; Watson, N. K.; Websdale, D.; Weiden, A.; Weisser, C.; Whitehead, M.; Wicht, J.; Wilkinson, G.; Wilkinson, M.; Williams, M.; Williams, M. P.; Williams, M.; Williams, T.; Wilson, F. F.; Wimberley, J.; Winn, M.; Wishahi, J.; Wislicki, W.; Witek, M.; Wormser, G.; Wotton, S. A.; Wraight, K.; Wyllie, K.; Xie, Y.; Xu, M.; Xu, Z.; Yang, Z.; Yang, Z.; Yao, Y.; Yin, H.; Yu, J.; Yuan, X.; Yushchenko, O.; Zarebski, K. A.; Zavertyaev, M.; Zhang, L.; Zhang, Y.; Zhelezov, A.; Zheng, Y.; Zhu, X.; Zhukov, V.; Zonneveld, J. B.; Zucchelli, S.; LHCb Collaboration

    2018-03-01

    A measurement is reported of the ratio of branching fractions R (J /ψ ) =B (Bc+→J /ψ τ+ντ)/B (Bc+→J /ψ μ+νμ) , where the τ+ lepton is identified in the decay mode τ+→μ+νμν¯τ. This analysis uses a sample of proton-proton collision data corresponding to 3.0 fb-1 of integrated luminosity recorded with the LHCb experiment at center-of-mass energies of 7 and 8 TeV. A signal is found for the decay Bc+→J /ψ τ+ντ at a significance of 3 standard deviations corrected for systematic uncertainty, and the ratio of the branching fractions is measured to be R (J /ψ ) =0.71 ±0.17 (stat ) ±0.18 (syst ) . This result lies within 2 standard deviations above the range of central values currently predicted by the standard model.

  9. Characterisation and molecular dynamic simulations of J15 asparaginase from Photobacterium sp. strain J15.

    PubMed

    Yaacob, Mohd Adilin; Hasan, Wan Atiqah Najiah Wan; Ali, Mohd Shukuri Mohamad; Rahman, Raja Noor Zaliha Raja Abdul; Salleh, Abu Bakar; Basri, Mahiran; Leow, Thean Chor

    2014-01-01

    Genome mining revealed a 1011 nucleotide-long fragment encoding a type I L-asparaginase (J15 asparaginase) from the halo-tolerant Photobacterium sp. strain J15. The gene was overexpressed in pET-32b (+) vector in E. coli strain Rosetta-gami B (DE3) pLysS and purified using two-step chromatographic methods: Ni(2+)-Sepharose affinity chromatography and Q-Sepharose anion exchange chromatography. The final specific activity and yield of the enzyme achieved from these steps were 20 U/mg and 49.2%, respectively. The functional dimeric form of J15-asparaginase was characterised with a molecular weight of ~70 kDa. The optimum temperature and pH were 25°C and pH 7.0, respectively. This protein was stable in the presence of 1 mM Ni(2+) and Mg(2+), but it was inhibited by Mn(2+), Fe(3+) and Zn(2+) at the same concentration. J15 asparaginase actively hydrolysed its native substrate, l-asparagine, but had low activity towards l-glutamine. The melting temperature of J15 asparaginase was ~51°C, which was determined using denatured protein analysis of CD spectra. The Km, Kcat, Kcat/Km of J15 asparaginase were 0.76 mM, 3.2 s(-1), and 4.21 s(-1) mM(-1), respectively. Conformational changes of the J15 asparaginase 3D structure at different temperatures (25°C, 45°C, and 65°C) were analysed using Molecular Dynamic simulations. From the analysis, residues Tyr₂₄ , His₂₂, Gly₂₃, Val₂₅ and Pro₂₆ may be directly involved in the 'open' and 'closed' lid-loop conformation, facilitating the conversion of substrates during enzymatic reactions. The properties of J15 asparaginase, which can work at physiological pH and has low glutaminase activity, suggest that this could be a good candidate for reducing toxic effects during cancer treatment.

  10. Elastic and inelastic photoproduction of J/ ψ mesons at HERA

    NASA Astrophysics Data System (ADS)

    Aid, S.; Andreev, V.; Andrieu, B.; Appuhn, R.-D.; Arpagaus, M.; Babaev, A.; Bähr, J.; Bán, J.; Ban, Y.; Baranov, P.; Barrelet, E.; Barschke, R.; Bartel, W.; Barth, M.; Bassler, U.; Beck, H. P.; Behrend, H.-J.; Belousov, A.; Berger, Ch.; Bernardi, G.; Bernet, R.; Bertrand-Coremans, G.; Besançon, M.; Beyer, R.; Biddulph, P.; Bispham, P.; Bizot, J. C.; Blobel, V.; Borras, K.; Botterweck, F.; Boudry, V.; Braemer, A.; Braunschweig, W.; Brisson, V.; Bruncko, D.; Brune, C.; Buchholz, R.; Büngener, L.; Bürger, J.; Büsser, F. W.; Buniatian, A.; Burke, S.; Burton, M. J.; Buschhorn, G.; Campbell, A. J.; Carli, T.; Charles, F.; Charlet, M.; Clarke, D.; Clegg, A. B.; Clerbaux, B.; Cocks, S.; Contreras, J. G.; Cormack, C.; Coughlan, J. A.; Courau, A.; Cousinou, M.-C.; Cozzika, G.; Criegee, L.; Cussans, D. G.; Cvach, J.; Dagoret, S.; Dainton, J. B.; Dau, W. D.; Daum, K.; David, M.; Davis, C. L.; Delcourt, B.; De Roeck, A.; De Wolf, E. A.; Dirkmann, M.; Dixon, P.; Di Nezza, P.; Dlugosz, W.; Dollfus, C.; Dowell, J. D.; Dreis, H. B.; Droutskoi, A.; Düllmann, D.; Dünger, O.; Duhm, H.; Ebert, J.; Ebert, T. R.; Eckerlin, G.; Efremenko, V.; Egli, S.; Eichler, R.; Eisele, F.; Eisenhandler, E.; Ellison, R. J.; Elsen, E.; Erdmann, M.; Erdmann, W.; Evrard, E.; Fahr, A. B.; Favart, L.; Fedotov, A.; Feeken, D.; Felst, R.; Feltesse, J.; Ferencei, J.; Ferrarotto, F.; Flamm, K.; Fleischer, M.; Flieser, M.; Flügge, G.; Fomenko, A.; Fominykh, B.; Formánek, J.; Foster, J. M.; Franke, G.; Fretwurst, E.; Gabathuler, E.; Gabathuler, K.; Gaede, F.; Garvey, J.; Gayler, J.; Gebauer, M.; Gellrich, A.; Genzel, H.; Gerhards, R.; Glazov, A.; Goerlach, U.; Goerlich, L.; Gogitidze, N.; Goldberg, M.; Goldner, D.; Golec-Biernat, K.; Gonzalez-Pineiro, B.; Gorelov, I.; Grab, C.; Grässler, H.; Grässler, R.; Greenshaw, T.; Griffiths, R.; Grindhammer, G.; Gruber, A.; Gruber, C.; Haack, J.; Haidt, D.; Hajduk, L.; Hampel, M.; Haynes, W. J.; Heinzelmann, G.; Henderson, R. C. W.; Henschel, H.; Herynek, I.; Hess, M. F.; Hildesheim, W.; Hiller, K. H.; Hilton, C. D.; Hladký, J.; Hoeger, K. C.; Höppner, M.; Hoffmann, D.; Holtom, T.; Horisberger, R.; Hudgson, V. L.; Hütte, M.; Hufnagel, H.; Ibbotson, M.; Itterbeck, H.; Jacholkowska, A.; Jacobsson, C.; Jaffre, M.; Janoth, J.; Jansen, T.; Jöhnson, L.; Johannsen, K.; Johnson, D. P.; Johnson, L.; Jung, H.; Kalmus, P. I. P.; Kander, M.; Kant, D.; Kaschowitz, R.; Kathage, U.; Katzy, J.; Kaufmann, H. H.; Kaufmann, O.; Kazarian, S.; Kenyon, I. R.; Kermiche, S.; Keuker, C.; Kiesling, C.; Klein, M.; Kleinwort, C.; Knies, G.; Köhler, T.; Köhne, J. H.; Kolanoski, H.; Kole, F.; Kolya, S. D.; Korbel, V.; Korn, M.; Kostka, P.; Kotelnikov, S. K.; Krämerkämper, T.; Krasny, M. W.; Krehbiel, H.; Krücker, D.; Krüger, U.; Krüner-Marquis, U.; Küster, H.; Kuhlen, M.; Kurča, T.; Kurzhöfer, J.; Lacour, D.; Laforge, B.; Lander, R.; Landon, M. P. J.; Lange, W.; Langenegger, U.; Laporte, J.-F.; Lebedev, A.; Lehner, F.; Leverenz, C.; Levonian, S.; Ley, Ch.; Lindström, G.; Lindstroem, M.; Link, J.; Linsel, F.; Lipinski, J.; List, B.; Lobo, G.; Lohmander, H.; Lomas, J. W.; Lopez, G. C.; Lubimov, V.; Lüke, D.; Magnussen, N.; Malinovski, E.; Mani, S.; Maraček, R.; Marage, P.; Marks, J.; Marshall, R.; Martens, J.; Martin, G.; Martin, R.; Martyn, H.-U.; Martyniak, J.; Mavroidis, T.; Maxfield, S. J.; McMahon, S. J.; Mehta, A.; Meier, K.; Merz, T.; Meyer, A.; Meyer, A.; Meyer, H.; Meyer, J.; Meyer, P.-O.; Migliori, A.; Mikocki, S.; Milstead, D.; Moeck, J.; Moreau, F.; Morris, J. V.; Mroczko, E.; Müller, D.; Müller, G.; Müller, K.; Murín, P.; Nagovizin, V.; Nahnhauer, R.; Naroska, B.; Naumann, Th.; Newman, P. R.; Newton, D.; Neyret, D.; Nguyen, H. K.; Nicholls, T. C.; Niebergall, F.; Niebuhr, C.; Niedzballa, Ch.; Niggli, H.; Nisius, R.; Nowak, G.; Noyes, G. W.; Nyberg-Werther, M.; Oakden, M.; Oberlack, H.; Obrock, U.; Olsson, J. E.; Ozerov, D.; Palmen, P.; Panaro, E.; Panitch, A.; Pascaud, C.; Patel, G. D.; Pawletta, H.; Peppel, E.; Perez, E.; Phillips, J. P.; Pieuchot, A.; Pitzl, D.; Pope, G.; Prell, S.; Prosi, R.; Rabbertz, K.; Rädel, G.; Raupach, F.; Reimer, P.; Reinshagen, S.; Rick, H.; Riech, V.; Riedlberger, J.; Riepenhausen, F.; Riess, S.; Rizvi, E.; Robertson, S. M.; Robmann, P.; Roloff, H. E.; Roosen, R.; Rosenbauer, K.; Rostovtsev, A.; Rouse, F.; Royon, C.; Rüter, K.; Rusakov, S.; Rybicki, K.; Sahlmann, N.; Sankey, D. P. C.; Schacht, P.; Schiek, S.; Schleif, S.; Schleper, P.; von Schlippe, W.; Schmidt, D.; Schmidt, G.; Schöning, A.; Schröder, V.; Schuhmann, E.; Schwab, B.; Sefkow, F.; Seidel, M.; Sell, R.; Semenov, A.; Shekelyan, V.; Sheviakov, I.; Shtarkov, L. N.; Siegmon, G.; Siewert, U.; Sirois, Y.; Skillicorn, I. O.; Smirnov, P.; Smith, J. R.; Solochenko, V.; Soloviev, Y.; Specka, A.; Spiekermann, J.; Spielman, S.; Spitzer, H.; Squinabol, F.; Starosta, R.; Steenbock, M.; Steffen, P.; Steinberg, R.; Steiner, H.; Stella, B.; Stellberger, A.; Stier, J.; Stiewe, J.; Stöβlein, U.; Stolze, K.; Straumann, U.; Struczinski, W.; Sutton, J. P.; Tapprogge, S.; Taševský, M.; Tchernyshov, V.; Tchetchelnitski, S.; Theissen, J.; Thiebaux, C.; Thompson, G.; Truöl, P.; Turnau, J.; Tutas, J.; Uelkes, P.; Usik, A.; Valkár, S.; Valkárová, A.; Vallée, C.; Vandenplas, D.; Van Esch, P.; Van Mechelen, P.; Vazdik, Y.; Verrecchia, P.; Villet, G.; Wacker, K.; Wagener, A.; Wagener, M.; Walther, A.; Waugh, B.; Weber, G.; Weber, M.; Wegener, D.; Wegner, A.; Wengler, T.; Werner, M.; West, L. R.; Wilksen, T.; Willard, S.; Winde, M.; Winter, G.-G.; Wittek, C.; Wünsch, E.; Žáček, J.; Zarbock, D.; Zhang, Z.; Zhokin, A.; Zimmer, M.; Zomer, F.; Zsembery, J.; Zuber, K.; zurNedden, M.; H1 Collaboration

    1996-02-01

    Results on J/ ψ production in ep interactions in the H1 experiment at HERA are presented. The J/ ψ mesons are produced by almost real photons ( Q2 ≈ 0) and detected via their leptonic decays. The data have been taken in 1994 and correspond to an integrated luminosity of 2.7 pb -1. The γp cross section for elastic J/ ψ production is observed to increase strongly with the center of mass energy. The cross section for diffractive J/ ψ production with proton dissociation is found to be of similar magnitude as the elastic cross section. Distributions of transverse momentum and decay angle are studied and found to be in accord with a diffractive production mechanism. For inelastic J/ ψ production the total γp cross section, the distribution of transverse momenta, and the elasticity of the J/ ψ are compared to NLO QCD calculations in a colour singlet model and agreement is found. Diffractive ψ' production has been observed and a first estimate of the ratio to J/ ψ production in the HERA energy regime is given.

  11. A radiative transfer module for calculating photolysis rates and solar heating in climate models: Solar-J v7.5

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hsu, Juno; Prather, Michael J.; Cameron-Smith, Philip

    Solar-J is a comprehensive radiative transfer model for the solar spectrum that addresses the needs of both solar heating and photochemistry in Earth system models. Solar-J is a spectral extension of Cloud-J, a standard in many chemical models that calculates photolysis rates in the 0.18–0.8 µm region. The Cloud-J core consists of an eight-stream scattering, plane-parallel radiative transfer solver with corrections for sphericity. Cloud-J uses cloud quadrature to accurately average over correlated cloud layers. It uses the scattering phase function of aerosols and clouds expanded to eighth order and thus avoids isotropic-equivalent approximations prevalent in most solar heating codes. Themore » spectral extension from 0.8 to 12 µm enables calculation of both scattered and absorbed sunlight and thus aerosol direct radiative effects and heating rates throughout the Earth's atmosphere. Furthermore, the Solar-J extension adopts the correlated-k gas absorption bins, primarily water vapor, from the shortwave Rapid Radiative Transfer Model for general circulation model (GCM) applications (RRTMG-SW). Solar-J successfully matches RRTMG-SW's tropospheric heating profile in a clear-sky, aerosol-free, tropical atmosphere. Here, we compare both codes in cloudy atmospheres with a liquid-water stratus cloud and an ice-crystal cirrus cloud. For the stratus cloud, both models use the same physical properties, and we find a systematic low bias of about 3 % in planetary albedo across all solar zenith angles caused by RRTMG-SW's two-stream scattering. Discrepancies with the cirrus cloud using any of RRTMG-SW's three different parameterizations are as large as about 20–40 % depending on the solar zenith angles and occur throughout the atmosphere. Effectively, Solar-J has combined the best components of RRTMG-SW and Cloud-J to build a high-fidelity module for the scattering and absorption of sunlight in the Earth's atmosphere, for which the three major components – wavelength

  12. A radiative transfer module for calculating photolysis rates and solar heating in climate models: Solar-J v7.5

    DOE PAGES

    Hsu, Juno; Prather, Michael J.; Cameron-Smith, Philip; ...

    2017-01-01

    Solar-J is a comprehensive radiative transfer model for the solar spectrum that addresses the needs of both solar heating and photochemistry in Earth system models. Solar-J is a spectral extension of Cloud-J, a standard in many chemical models that calculates photolysis rates in the 0.18–0.8 µm region. The Cloud-J core consists of an eight-stream scattering, plane-parallel radiative transfer solver with corrections for sphericity. Cloud-J uses cloud quadrature to accurately average over correlated cloud layers. It uses the scattering phase function of aerosols and clouds expanded to eighth order and thus avoids isotropic-equivalent approximations prevalent in most solar heating codes. Themore » spectral extension from 0.8 to 12 µm enables calculation of both scattered and absorbed sunlight and thus aerosol direct radiative effects and heating rates throughout the Earth's atmosphere. Furthermore, the Solar-J extension adopts the correlated-k gas absorption bins, primarily water vapor, from the shortwave Rapid Radiative Transfer Model for general circulation model (GCM) applications (RRTMG-SW). Solar-J successfully matches RRTMG-SW's tropospheric heating profile in a clear-sky, aerosol-free, tropical atmosphere. Here, we compare both codes in cloudy atmospheres with a liquid-water stratus cloud and an ice-crystal cirrus cloud. For the stratus cloud, both models use the same physical properties, and we find a systematic low bias of about 3 % in planetary albedo across all solar zenith angles caused by RRTMG-SW's two-stream scattering. Discrepancies with the cirrus cloud using any of RRTMG-SW's three different parameterizations are as large as about 20–40 % depending on the solar zenith angles and occur throughout the atmosphere. Effectively, Solar-J has combined the best components of RRTMG-SW and Cloud-J to build a high-fidelity module for the scattering and absorption of sunlight in the Earth's atmosphere, for which the three major components – wavelength

  13. Pair production of J/ψ mesons in the kt-factorization approach

    NASA Astrophysics Data System (ADS)

    Baranov, S. P.

    2011-09-01

    In the framework of kt-factorization approach, we consider the production of J/ψ pairs at the LHC conditions. We give predictions on the differential cross sections and discuss the source and the size of theoretical uncertainties. We also present a comparison with collinear parton model showing a dramatic difference in the J/ψ transverse momentum spectrum and J/ψ-J/ψ azimuthal correlations. Finally, we give predictions on the polarization observables in the helicity and Collins-Soper systems.

  14. Maternal Weight Gain as a Predictor of Litter Size in Swiss Webster, C57BL/6J, and BALB/cJ mice.

    PubMed

    Finlay, James B; Liu, Xueli; Ermel, Richard W; Adamson, Trinka W

    2015-11-01

    An important task facing both researchers and animal core facilities is producing sufficient mice for a given project. The inherent biologic variability of mouse reproduction and litter size further challenges effective research planning. A lack of precision in project planning contributes to the high cost of animal research, overproduction (thus waste) of animals, and inappropriate allocation of facility resources. To examine the extent daily prepartum maternal weight gain predicts litter size in 2 commonly used mouse strains (BALB/cJ and C57BL/6J) and one mouse stock (Swiss Webster), we weighed ≥ 25 pregnant dams of each strain or stock daily from the morning on which a vaginal plug (day 0) was present. On the morning when dams delivered their pups, we recorded the weight of the dam, the weight of the litter itself, and the number of pups. Litter sizes ranged from 1 to 7 pups for BALB/cJ, 2 to 13 for Swiss Webster, and 5 to 11 for C57BL/6J mice. Linear regression models (based on weight change from day 0) demonstrated that maternal weight gain at day 9 (BALB/cJ), day 11 (Swiss Webster), or day 14 (C57BL/6J) was a significant predictor of litter size. When tested prospectively, the linear regression model for each strain or stock was found to be accurate. These data indicate that the number of pups that will be born can be estimated accurately by using maternal weight gain at specific or stock-specific time points.

  15. J-2X engine assembly

    NASA Image and Video Library

    2011-03-03

    Pratt & Whitney Rocketdyne employees Carlos Alfaro (l) and Oliver Swanier work on the main combustion element of the J-2X rocket engine at their John C. Stennis Space Center facility. Assembly of the J-2X rocket engine to be tested at the site is under way, with completion and delivery to the A-2 Test Stand set for June. The J-2X is being developed as a next-generation engine that can carry humans into deep space. Stennis Space Center is preparing a trio of stands to test the new engine.

  16. Natural disease history of the dy2J mouse model of laminin α2 (merosin)-deficient congenital muscular dystrophy.

    PubMed

    Pasteuning-Vuhman, S; Putker, K; Tanganyika-de Winter, C L; Boertje-van der Meulen, J W; van Vliet, L; Overzier, M; Plomp, J J; Aartsma-Rus, A; van Putten, M

    2018-01-01

    Merosin deficient congenital muscular dystrophy 1A (MDC1A) is a very rare autosomal recessive disorder caused by mutations in the LAMA2 gene leading to severe and progressive muscle weakness and atrophy. Although over 350 causative mutations have been identified for MDC1A, no treatment is yet available. There are many therapeutic approaches in development, but the lack of natural history data of the mouse model and standardized outcome measures makes it difficult to transit these pre-clinical findings to clinical trials. Therefore, in the present study, we collected natural history data and assessed pre-clinical outcome measures for the dy2J/dy2J mouse model using standardized operating procedures available from the TREAT-NMD Alliance. Wild type and dy2J/dy2J mice were subjected to five different functional tests from the age of four to 32 weeks. Non-tested control groups were taken along to assess whether the functional test regime interfered with muscle pathology. Respiratory function, body weights and creatine kinase levels were recorded. Lastly, skeletal muscles were collected for further histopathological and gene expression analyses. Muscle function of dy2J/dy2J mice was severely impaired at four weeks of age and all mice lost the ability to use their hind limbs. Moreover, respiratory function was altered in dy2J/dy2J mice. Interestingly, the respiration rate was decreased and declined with age, whereas the respiration amplitude was increased in dy2J/dy2J mice when compared to wild type mice. Creatine kinase levels were comparable to wild type mice. Muscle histopathology and gene expression analysis revealed that there was a specific regional distribution pattern of muscle damage in dy2J/dy2J mice. Gastrocnemius appeared to be the most severely affected muscle with a high proportion of atrophic fibers, increased fibrosis and inflammation. By contrast, triceps was affected moderately and diaphragm only mildly. Our study presents a complete natural history

  17. Transcription factor RBP-J-mediated signalling regulates basophil immunoregulatory function in mouse asthma model.

    PubMed

    Qu, Shuo-Yao; He, Ya-Long; Zhang, Jian; Wu, Chang-Gui

    2017-09-01

    Basophils (BA) play an important role in the promotion of aberrant T helper type 2 (Th2) immune responses in asthma. It is not only the effective cell, but also modulates the initiation of Th2 immune responses. We earlier demonstrated that Notch signalling regulates the biological function of BAin vitro. However, whether this pathway plays the same role in vivo is not clear. The purpose of the present study was to investigate the effect of Notch signalling on BA function in the regulation of allergic airway inflammation in a murine model of asthma. Bone marrow BA were prepared by bone marrow cell culture in the presence of recombinant interleukin-3 (rIL-3; 300 pg/ml) for 7 days, followed by isolation of the CD49b + microbeads. The recombination signal binding protein J (RBP-J -/- ) BA were co-cultured with T cells, and the supernatant and the T-cell subtypes were examined. The results indicated disruption of the capacity of BA for antigen presentation alongside an up-regulation of the immunoregulatory function. This was possibly due to the low expression of OX40L in the RBP-J -/- BA. Basophils were adoptively transferred to ovalbumin-sensitized recipient mice, to establish an asthma model. Lung pathology, cytokine profiles of brobchoalveolar fluid, airway hyperactivity and the absolute number of Th1/Th2 cells in lungs were determined. Overall, our results indicate that the RBP-J-mediated Notch signalling is critical for BA-dependent immunoregulation. Deficiency of RBP-J influences the immunoregulatory functions of BA, which include activation of T cells and their differentiation into T helper cell subtypes. The Notch signalling pathway is a potential therapeutic target for BA-based immunotherapy against asthma. © 2017 John Wiley & Sons Ltd.

  18. Intertwined order in a frustrated four-leg t - J cylinder

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dodaro, John F.; Jiang, Hong -Chen; Kivelson, Steven A.

    Here, we report a density-matrix renormalization group study of the t–J model with nearest (t 1 and J 1) and next-nearest (t 2 and J 2) interactions on a four-leg cylinder with concentration δ=1/8 of doped holes. We observe an astonishingly complex interplay between uniform d-wave superconductivity (SC) and strong spin and charge-density wave ordering tendencies (SDW and CDW). Depending on parameters, the CDWs can be commensurate with period 4 or 8. By comparing the charge ordering vectors with 2k F, we rule out Fermi surface nesting-induced density wave order in our model. Magnetic frustration (i.e., J 2/J 1~1/2) significantlymore » quenches SDW correlations with little effect on the CDW. Typically, the SC order is strongly modulated at the CDW ordering vector and exhibits d-wave symmetry around the cylinder. There is no evidence of a near-degenerate tendency to pair-density wave (PDW) ordering, charge 4e SC, or orbital current order.« less

  19. Intertwined order in a frustrated four-leg t - J cylinder

    DOE PAGES

    Dodaro, John F.; Jiang, Hong -Chen; Kivelson, Steven A.

    2017-04-12

    Here, we report a density-matrix renormalization group study of the t–J model with nearest (t 1 and J 1) and next-nearest (t 2 and J 2) interactions on a four-leg cylinder with concentration δ=1/8 of doped holes. We observe an astonishingly complex interplay between uniform d-wave superconductivity (SC) and strong spin and charge-density wave ordering tendencies (SDW and CDW). Depending on parameters, the CDWs can be commensurate with period 4 or 8. By comparing the charge ordering vectors with 2k F, we rule out Fermi surface nesting-induced density wave order in our model. Magnetic frustration (i.e., J 2/J 1~1/2) significantlymore » quenches SDW correlations with little effect on the CDW. Typically, the SC order is strongly modulated at the CDW ordering vector and exhibits d-wave symmetry around the cylinder. There is no evidence of a near-degenerate tendency to pair-density wave (PDW) ordering, charge 4e SC, or orbital current order.« less

  20. Differences in aggressive behavior and DNA copy number variants between BALB/cJ and BALB/cByJ substrains.

    PubMed

    Velez, Lady; Sokoloff, Greta; Miczek, Klaus A; Palmer, Abraham A; Dulawa, Stephanie C

    2010-03-01

    Some BALB/c substrains exhibit different levels of aggression. We compared aggression levels between male BALB/cJ and BALB/cByJ substrains using the resident intruder paradigm. These substrains were also assessed in other tests of emotionality and information processing including the open field, forced swim, fear conditioning, and prepulse inhibition tests. We also evaluated single nucleotide polymorphisms (SNPs) previously reported between these BALB/c substrains. Finally, we compared BALB/cJ and BALB/cByJ mice for genomic deletions or duplications, collectively termed copy number variants (CNVs), to identify candidate genes that might underlie the observed behavioral differences. BALB/cJ mice showed substantially higher aggression levels than BALB/cByJ mice; however, only minor differences in other behaviors were observed. None of the previously reported SNPs were verified. Eleven CNV regions were identified between the two BALB/c substrains. Our findings identify a robust difference in aggressive behavior between BALB/cJ and BALB/cByJ substrains, which could be the result of the identified CNVs.

  1. A search for the presence of magnetic fields in the two supergiant fast X-ray transients, IGR J08408-4503 and IGR J11215-5952

    NASA Astrophysics Data System (ADS)

    Hubrig, S.; Sidoli, L.; Postnov, K.; Schöller, M.; Kholtygin, A. F.; Järvinen, S. P.; Steinbrunner, P.

    2018-02-01

    A significant fraction of high-mass X-ray binaries are supergiant fast X-ray transients (SFXTs). The prime model for the physics governing their X-ray behaviour suggests that the winds of donor OB supergiants are magnetized. To investigate if magnetic fields are indeed present in the optical counterparts of such systems, we acquired low-resolution spectropolarimetric observations of the two optically brightest SFXTs, IGR J08408-4503 and IGR J11215-5952, with the ESO FORS 2 instrument during two different observing runs. No field detection at a significance level of 3σ was achieved for IGR J08408-4503. For IGR J11215-5952, we obtain 3.2σ and 3.8σ detections (⟨Bz⟩hydr = -978 ± 308 G and ⟨Bz⟩hydr = 416 ± 110 G) on two different nights in 2016. These results indicate that the model involving the interaction of a magnetized stellar wind with the neutron star magnetosphere can indeed be considered to characterize the behaviour of SFXTs. We detected long-term spectral variability in IGR J11215-5952, whereas for IGR J08408-4503, we find an indication of the presence of short-term variability on a time-scale of minutes.

  2. GeV Detection of HESS J0632+057

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, Jian; Torres, Diego F.; Wilhelmi, Emma de Oña

    2017-09-10

    HESS J0632+057 is the only gamma-ray binary that has been detected at TeV energies, but not at GeV energies yet. Based on nearly nine years of Fermi Large Area Telescope (LAT) Pass 8 data, we report here on a deep search for the gamma-ray emission from HESS J0632+057 in the 0.1–300 GeV energy range. We find a previously unknown gamma-ray source, Fermi J0632.6+0548, spatially coincident with HESS J0632+057. The measured flux of Fermi J0632.6+0548 is consistent with the previous flux upper limit on HESS J0632+057 and shows variability that can be related to the HESS J0632+057 orbital phase. We proposemore » that Fermi J0632.6+0548 is the GeV counterpart of HESS J0632+057. Considering the Very High Energy spectrum of HESS J0632+057, a possible spectral turnover above 10 GeV may exist in Fermi J0632.6+0548, as appears to be common in other established gamma-ray binaries.« less

  3. Effects of Dorzolamide on Retinal and Choroidal Blood Flow in the DBA/2J Mouse Model of Glaucoma

    PubMed Central

    Chandra, Saurav; Muir, Eric R.; Deo, Kaiwalya; Kiel, Jeffrey W.; Duong, Timothy Q.

    2016-01-01

    Purpose To test the hypothesis that acute topical dorzolamide (DZ) decreases intraocular pressure (IOP) and increases retinal and choroidal blood flow in the DBA/2J mouse model of glaucoma. Methods Retinal and choroidal blood flow were measured in 4- and 9-month-old DBA/2J mice, and 4-month C57BL/6 (control) mice under isoflurane anesthesia using magnetic resonance imaging. Ocular blood flow was measured at baseline, and 1 and 2 hours after topical dorzolamide. Intraocular pressure was measured using a rebound tonometer in a subset of animals at the same time points. Results Baseline IOP in the 4-month-old DBA/2J mice and C57BL/6 mice was not significantly different (P > 0.05), and IOP in both groups was less than in the 9-month-old DBA/2J mice (P < 0.05 for both). Compared to baseline, dorzolamide reduced IOP at 1 and 2 hours after dorzolamide in the 4- (P < 0.05) and 9-month-old (P < 0.01) DBA/2J mice, but not in the C57BL/6J mice (P > 0.05). Baseline retinal blood flow was lower in the 4-month and 9-month-old DBA/2J mice compared with the 4-month-old C57BL/6J mice (P < 0.05). Baseline choroidal blood flow in the 9-month-old DBA/2J mice was less than in the C57BL/6J mice (P < 0.05). Compared with baseline, both retinal and choroidal blood flow increased at 1-hour post-dorzolamide and remained elevated 2 hours later in the 9-month-old DBA/2J mice (P < 0.05). Conclusions Dorzolamide lowers IOP and raises retinal and choroidal blood flow in older DBA/2J mice, consistent with the study hypothesis. PMID:26934140

  4. WISEP J061135.13-041024.0 AB: A J-band Flux Reversal Binary at the L/T Transition

    NASA Astrophysics Data System (ADS)

    Gelino, Christopher R.; Smart, R. L.; Marocco, Federico; Kirkpatrick, J. Davy; Cushing, Michael C.; Mace, Gregory; Mendez, Rene A.; Tinney, C. G.; Jones, Hugh R. A.

    2014-07-01

    We present Keck II laser guide star adaptive optics observations of the brown dwarf WISEP J061135.13-041024.0 showing it is a binary with a component separation of 0.''4. This system is one of the six known resolved binaries in which the magnitude differences between the components show a reversal in sign between the Y/J band and the H/K bands. Deconvolution of the composite spectrum results in a best-fit binary solution with L9 and T1.5 components. We also present a preliminary parallax placing the system at a distance of 21.2 ± 1.3 pc. Using the distance and resolved magnitudes we are able to place WISEP J061135.13-041024.0 AB on a color-absolute magnitude diagram, showing that this system contributes to the well-known "J-band bump" and the components' properties appear similar to other late-type L and early-type T dwarfs. Fitting our data to a set of cloudy atmosphere models suggests the system has an age >1 Gyr with WISE 0611-0410 A having an effective temperature (T eff) of 1275-1325 K and mass of 64-65 M Jup, and WISE 0611-0410 B having T eff = 1075-1115 K and mass 40-65 M Jup.

  5. Gapped paramagnetic state in a frustrated spin-1/2 Heisenberg antiferromagnet on the cross-striped square lattice

    NASA Astrophysics Data System (ADS)

    Li, P. H. Y.; Bishop, R. F.

    2018-03-01

    We implement the coupled cluster method to very high orders of approximation to study the spin-1/2 J1 -J2 Heisenberg model on a cross-striped square lattice. Every nearest-neighbour pair of sites on the square lattice has an isotropic antiferromagnetic exchange bond of strength J1 > 0 , while the basic square plaquettes in alternate columns have either both or neither next-nearest-neighbour (diagonal) pairs of sites connected by an equivalent frustrating bond of strength J2 ≡ αJ1 > 0 . By studying the magnetic order parameter (i.e., the average local on-site magnetization) in the range 0 ≤ α ≤ 1 of the frustration parameter we find that the quasiclassical antiferromagnetic Néel and (so-called) double Néel states form the stable ground-state phases in the respective regions α < α1ac = 0 . 46(1) and α > α1bc = 0.615(5) . The double Néel state has Néel (⋯ ↑↓↑↓ ⋯) ordering along the (column) direction parallel to the stripes of squares with both or no J2 bonds, and spins alternating in a pairwise (⋯ ↑↑↓↓↑↑↓↓ ⋯) fashion along the perpendicular (row) direction, so that the parallel pairs occur on squares with both J2 bonds present. Further explicit calculations of both the triplet spin gap and the zero-field uniform transverse magnetic susceptibility provide compelling evidence that the ground-state phase over all or most of the intermediate regime α1ac < α < α1bc is a gapped state with no discernible long-range magnetic order.

  6. Spectrophotometry of J8, J9, and four Trojan asteroids from 0.32 to 1.05 microns

    NASA Technical Reports Server (NTRS)

    Smith, D. W.; Johnson, P. E.; Shorthill, R. W.

    1981-01-01

    New 30-channel narrowband photometry from 0.32 to 1.05 microns of the retrograde Jovian satellites J9 (to 0.7 micron) and J8 and the trailing Trojan asteroids 617, 884, 1172, and 1173 is presented. The data confirm previous measurements of J8, 617, 884, and 1172 at wavelengths less than 0.8 micron, but the extension into the infrared shows that the normalized spectral reflectance of these objects rises steadily from approximately 0.8 at 0.4 micron to approximately 1.4 at 1.05 microns, suggesting they are too bright in the near infrared to be C-type asteroids. The C classification of 1173 is confirmed. J9 is markedly redder than J8 at visible wavelengths. The results indicate a greater taxonomic contrast between these distant objects and main-belt asteroids than previously thought.

  7. Mid-UV studies of the transitional millisecond pulsars XSS J12270-4859 and PSR J1023+0038 during their radio pulsar states

    NASA Astrophysics Data System (ADS)

    Rivera Sandoval, L. E.; Hernández Santisteban, J. V.; Degenaar, N.; Wijnands, R.; Knigge, C.; Miller, J. M.; Reynolds, M.; Altamirano, D.; van den Berg, M.; Hill, A.

    2018-05-01

    We report mid-UV (MUV) observations taken with Hubble Space Telescope (HST)/WFC3, Swift/UVOT, and GALEX/NUV of the transitional millisecond pulsars XSS J12270-4859 and PSR J1023+0038 during their radio pulsar states. Both systems were detected in our images and showed MUV variability. At similar orbital phases, the MUV luminosities of both pulsars are comparable. This suggests that the emission processes involved in both objects are similar. We estimated limits on the mass ratio, companion's temperature, inclination, and distance to XSS J12270-4859 by using a Markov Chain Monte Carlo algorithm to fit published folded optical light curves. Using the resulting parameters, we modelled MUV light curves in our HST filters. The resulting models failed to fit our MUV observations. Fixing the mass ratio of XSS J12270-4859 to the value reported in other studies, we obtained a distance of ˜3.2 kpc. This is larger than the one derived from dispersion measure (˜1.4 kpc). Assuming a uniform prior for the mass ratio, the distance is similar to that from radio measurements. However, it requires an undermassive companion (˜0.01M⊙). We conclude that a direct heating model alone cannot fully explain the observations in optical and MUV. Therefore, an additional radiation source is needed. The source could be an intrabinary shock which contributes to the MUV flux and likely to the optical one as well. During the radio pulsar state, the MUV orbital variations of PSR J1023+0038 detected with GALEX, suggest the presence of an asymmetric intrabinary shock.

  8. 75 FR 18254 - R.J. Corman Railroad Company/Bardstown Line-Lease and Operation Exemption-R.J. Corman Railroad...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-09

    ... DEPARTMENT OF TRANSPORTATION Surface Transportation Board [STB Finance Docket No. 35364] R.J. Corman Railroad Company/Bardstown Line--Lease and Operation Exemption--R.J. Corman Railroad Property, LLC R.J. Corman Railroad Company/Bardstown Line (RJC Railroad Company), a Class III rail carrier, has...

  9. J Wave Syndromes: History and Current Controversies

    PubMed Central

    Liu, Tong; Zheng, Jifeng

    2016-01-01

    The concept of J wave syndromes was first proposed in 2004 by Yan et al for a spectrum of electrocardiographic (ECG) manifestations of prominent J waves that are associated with a potential to predispose affected individuals to ventricular fibrillation (VF). Although the concept of J wave syndromes is widely used and accepted, there has been tremendous debate over the definition of J wave, its ionic and cellular basis and arrhythmogenic mechanism. In this review article, we attempted to discuss the history from which the concept of J wave syndromes (JWS) is evolved and current controversies in JWS. PMID:27721848

  10. Broadband Spectral Investigations of SGR J1550-5418 Bursts

    NASA Technical Reports Server (NTRS)

    Lin, Lin; Goegues, Ersin; Baring, Matthew G.; Granot, Jonathan; Kouveliotou, Chryssa; Kaneko, Yuki; van der Horst, Alexander; Gruber, David; von Kienlin, Andreas; Younes, George; hide

    2012-01-01

    We present the results of our broadband spectral analysis of 42 SGR J1550-5418 bursts simultaneously detected with the Swift/X-ray Telescope (XRT) and the Fermi/Gamma-ray Burst Monitor (GBM), during the 2009 January active episode of the source. The unique spectral and temporal capabilities of the XRT windowed timing mode have allowed us to extend the GBM spectral coverage for these events down to the X-ray domain (0.5-10 keV). Our earlier analysis of the GBM data found that the SGR J1550-5418 burst spectra were described equally well with either a Comptonized model or with two blackbody functions; the two models were statistically indistinguishable. Our new broadband (0.5-200 keV) spectral fits show that, on average, the burst spectra are better described with two blackbody functions than with the Comptonized model. Thus, our joint XRT-GBM analysis clearly shows for the first time that the SGR J1550-5418 burst spectra might naturally be expected to exhibit a more truly thermalized character, such as a two-blackbody or even a multi-blackbody signal. Using the Swift and RXTE timing ephemeris for SGR J1550-5418 we construct the distribution of the XRT burst counts with spin phase and find that it is not correlated with the persistent X-ray emission pulse phase from SGR J1550-5418. These results indicate that the burst emitting sites on the neutron star need not to be co-located with hot spots emitting the bulk of the persistent X-ray emission. Finally, we show that there is a significant pulse phase dependence of the XRT burst counts, likely demonstrating that the surface magnetic field of SGR J1550-5418 is not uniform over the emission zones, since it is anticipated that regions with stronger surface magnetic field could trigger bursts more efficiently.

  11. Self consistent solution of the tJ model in the overdoped regime

    NASA Astrophysics Data System (ADS)

    Shastry, B. Sriram; Hansen, Daniel

    2013-03-01

    Detailed results from a recent microscopic theory of extremely correlated Fermi liquids, applied to the t-J model in two dimensions, are presented. The theory is to second order in a parameter λ, and is valid in the overdoped regime of the tJ model. The solution reported here is from Ref, where relevant equations given in Ref are self consistently solved for the square lattice. Thermodynamic variables and the resistivity are displayed at various densities and T for two sets of band parameters. The momentum distribution function and the renormalized electronic dispersion, its width and asymmetry are reported along principal directions of the zone. The optical conductivity is calculated. The electronic spectral function A (k , ω) probed in ARPES, is detailed with different elastic scattering parameters to account for the distinction between LASER and synchrotron ARPES. A high (binding) energy waterfall feature, sensitively dependent on the band hopping parameter t' is noted. This work was supported by DOE under Grant No. FG02-06ER46319.

  12. First observation of associated production of J/psi meson and W boson

    NASA Astrophysics Data System (ADS)

    Melachrinos, Constantinos

    Particle physics concerns the understanding of the fundamental building blocks of nature, the production of particles and their interactions. The experimental study of high energy collisions allows us to probe the theoretical predictions pertaining to particles. The Large Hadron Collider was built on the outskirts of Geneva, to accelerate and collide protons at the highest energies ever, and allow for the study of the products of these collisions. The ATLAS detector is designed to detect the particles resulting from the proton-proton collisions and collect the data for further study. The discovery of the J/psi meson in 1974 paved the way for the presence of three families of quarks in the Standard Model of Particle Physics. The production mechanism of J/psi at the LHC is not well understood, and several models have been proposed to explain it, such as the Color Singlet and Color Octet models. The associated production of J/psi meson with a W boson offers an additional insight on the production of J/psi. In this thesis, we report the first observation of the W +/- + J/psi production using 4.5 fb -1 of ATLAS data from proton-proton collisions at center of mass energy of 7 TeV at the Large Hadron Collider. In addition, we measure the cross-section ratio of the W+/- + J/psi production to the inclusive W production. The results are dominated by statistical uncertainties and suggest that a combination of the different models for J/psi production is needed to explain J/psi production.

  13. Detection of J-coupling using atomic magnetometer

    DOEpatents

    Ledbetter, Micah P.; Crawford, Charles W.; Wemmer, David E.; Pines, Alexander; Knappe, Svenja; Kitching, John; Budker, Dmitry

    2015-09-22

    An embodiment of a method of detecting a J-coupling includes providing a polarized analyte adjacent to a vapor cell of an atomic magnetometer; and measuring one or more J-coupling parameters using the atomic magnetometer. According to an embodiment, measuring the one or more J-coupling parameters includes detecting a magnetic field created by the polarized analyte as the magnetic field evolves under a J-coupling interaction.

  14. Sequence stratigraphy and reservoir architecture of the J18/20 and J15 sequences in PM-9, Malay Basin

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rahman, R.A.; Said, Md.J.; Bedingfield, J.R.

    1994-07-01

    The group J stratigraphic interval is lower Miocene (18.5-21 Ma) in age and was deposited during the early sag phase of the Malay Basin structural development. Reduction in depositional relief and first evidence of widespread marine influence characterize the transition into this interval. Twelve group J sequences have been identified. Reservoirs consist of progradational to aggradational tidally-dominated paralic to shallow marine sands deposited in the lowstand systems tract. Transgressive and highstand deposits are dominantly offshore shales. In PM-9, the original lift-related depocenters, coupled with changes in relative sea level, have strongly influenced group J unit thickness and the distribution ofmore » reservoir and seal facies. Two important reservoir intervals in PM-9 are the J18/20 and J15 sands. The reservoirs in these intervals are contained within the lowstand systems tracts of fourth-order sequences. These fourth-order sequences stack to form sequence sets in response to a third-order change in relative sea level. The sequences of the J18/20 interval stack to form part of a lowstand sequence set, whereas the J15 interval forms part of the transgressive sequence set. Reservoir facies range from tidal bars and subtidal shoals in the J18/20 interval to lower shoreface sands in the J15. Reservoir quality and continuity in group J reservoirs are dependent on depositional facies. An understanding of the controls on the distribution of facies types is crucial to the success of the current phase of field development and exploration programs in PM-9.« less

  15. Ethanol teratogenesis in the C57BL/6J, DBA/2J, and A/J inbred mouse strains.

    PubMed

    Boehm, S L; Lundahl, K R; Caldwell, J; Gilliam, D M

    1997-01-01

    Research has shown variations in susceptibility to alcohol-related birth defects in humans. Genetic differences are one reason for this variability. This study compared three inbred mouse strains to determine whether they differ in their susceptibilities to ethanol teratogenesis because previous studies have generated conflicting data. Pregnant C57BL/6J (B6), DBA/2J (D2), and A/J (A) dams were intubated intragastrically with either an acute dose of ethanol (5.8 g/kg) or an isocaloric amount of maltose-dextrine on day 9 of pregnancy. Litters were removed on day 18 of pregnancy and examined for gross, soft-tissue, and skeletal malformations. Results showed that ethanol-exposed B6 litters had a higher percentage of digit (19%), kidney (24%), and skeletal (32%, mostly vertebral) malformations than their maltose-exposed controls (7% or below). Prenatal exposure to ethanol increased skeletal (68%, both rib and vertebral) malformations for A litters when compared to their maltose-exposed controls (4%), but did not increase digit or kidney malformations. Ethanol-exposed D2 litters did not differ from maltose-exposed controls. Maternal blood ethanol levels did not differ among the B6, D2, and A strains. These results provide additional evidence suggesting a genetic component to ethanol teratogenesis.

  16. Modeling Chemistry for Effective Chemical Education: An Interview with Ronald J. Gillespie

    ERIC Educational Resources Information Center

    Cardellini, Liberato

    2010-01-01

    Ronald J. Gillespie, the inventor of the Valence Shell Electron Pair Repulsion (VSEPR) model, relates how his career as researcher in Christopher Ingold's laboratories started. Gillespie developed a passion for chemistry and chemical education, searching for more appropriate and interesting ways to transmit the essential knowledge and enthusiasm…

  17. A Study of the Optical Components of the Hard X-Ray Sources IGR J17544-2619 and IGR J21343+4738 by Using RTT-150 Observations

    NASA Astrophysics Data System (ADS)

    Nikolaeva, E. A.; Bikmaev, I. F.; Shimansky, V. V.; Sakhibullin, N. A.

    2017-06-01

    We investigate parameters of two high-mass X-ray binary systems IGR J17544-2619 and IGR J21343+4738 discovered by INTEGRAL space observatory by using optical data of Russian Turkish Telescope (RTT-150). Long-term optical observations of X-ray binary systems IGR J17544-2619 and IGR J21343+4738 were carried out in 2007-2015. Based on the RTT-150 data we estimated orbital periods of these systems. We have modeled the profiles of line HeI 6678 Å in spectra of studied optical stars and obtain the parameters of the star's atmosphere.

  18. j5 DNA assembly design automation.

    PubMed

    Hillson, Nathan J

    2014-01-01

    Modern standardized methodologies, described in detail in the previous chapters of this book, have enabled the software-automated design of optimized DNA construction protocols. This chapter describes how to design (combinatorial) scar-less DNA assembly protocols using the web-based software j5. j5 assists biomedical and biotechnological researchers construct DNA by automating the design of optimized protocols for flanking homology sequence as well as type IIS endonuclease-mediated DNA assembly methodologies. Unlike any other software tool available today, j5 designs scar-less combinatorial DNA assembly protocols, performs a cost-benefit analysis to identify which portions of an assembly process would be less expensive to outsource to a DNA synthesis service provider, and designs hierarchical DNA assembly strategies to mitigate anticipated poor assembly junction sequence performance. Software integrated with j5 add significant value to the j5 design process through graphical user-interface enhancement and downstream liquid-handling robotic laboratory automation.

  19. The Spacelab J mission

    NASA Technical Reports Server (NTRS)

    Cremin, J. W.; Leslie, F. W.

    1990-01-01

    This paper describes Spacelab J (SL-J), its mission characteristics, features, parameters and configuration, the unique nature of the shared reimbursable cooperative effort with the National Space Development Agency (NASDA) of Japan and the evolution, content and objectives of the mission scientific experiment complement. The mission is planned for launch in 1991. This long module mission has 35 experiments from Japan as well as 9 investigations from the United States. The SL-J payload consists of two broad scientific disciplines which require the extended microgravity or cosmic ray environment: (1) materials science such as crystal growth, solidification processes, drop dynamics, free surface flows, gas dynamics, metallurgy and semiconductor technology; and (2) life science including cell development, human physiology, radiation-induced mutations, vestibular studies, embryo development, and medical technology. Through an international agreement with NASDA, NASA is preparing to fly the first Japanese manned, scientific, cooperative endeavor with the United States.

  20. 75 FR 20774 - Modification of Jet Routes J-37 and J-55; Northeast United States

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-21

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 [Docket No. FAA-2010-0003; Airspace Docket No. 09-ANE-104] Modification of Jet Routes J-37 and J-55; Northeast United States AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action modifies Jet...

  1. The JBEI quantitative metabolic modeling library (jQMM): a python library for modeling microbial metabolism.

    PubMed

    Birkel, Garrett W; Ghosh, Amit; Kumar, Vinay S; Weaver, Daniel; Ando, David; Backman, Tyler W H; Arkin, Adam P; Keasling, Jay D; Martín, Héctor García

    2017-04-05

    Modeling of microbial metabolism is a topic of growing importance in biotechnology. Mathematical modeling helps provide a mechanistic understanding for the studied process, separating the main drivers from the circumstantial ones, bounding the outcomes of experiments and guiding engineering approaches. Among different modeling schemes, the quantification of intracellular metabolic fluxes (i.e. the rate of each reaction in cellular metabolism) is of particular interest for metabolic engineering because it describes how carbon and energy flow throughout the cell. In addition to flux analysis, new methods for the effective use of the ever more readily available and abundant -omics data (i.e. transcriptomics, proteomics and metabolomics) are urgently needed. The jQMM library presented here provides an open-source, Python-based framework for modeling internal metabolic fluxes and leveraging other -omics data for the scientific study of cellular metabolism and bioengineering purposes. Firstly, it presents a complete toolbox for simultaneously performing two different types of flux analysis that are typically disjoint: Flux Balance Analysis and 13 C Metabolic Flux Analysis. Moreover, it introduces the capability to use 13 C labeling experimental data to constrain comprehensive genome-scale models through a technique called two-scale 13 C Metabolic Flux Analysis (2S- 13 C MFA). In addition, the library includes a demonstration of a method that uses proteomics data to produce actionable insights to increase biofuel production. Finally, the use of the jQMM library is illustrated through the addition of several Jupyter notebook demonstration files that enhance reproducibility and provide the capability to be adapted to the user's specific needs. jQMM will facilitate the design and metabolic engineering of organisms for biofuels and other chemicals, as well as investigations of cellular metabolism and leveraging -omics data. As an open source software project, we hope it will

  2. SPECTRUM AND MORPHOLOGY OF THE TWO BRIGHTEST MILAGRO SOURCES IN THE CYGNUS REGION: MGRO J2019+37 AND MGRO J2031+41

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Abdo, A. A.; Abeysekara, U.; Linnemann, J. T.

    2012-07-10

    The Cygnus region is a very bright and complex portion of the TeV sky, host to unidentified sources and a diffuse excess with respect to conventional cosmic-ray propagation models. Two of the brightest TeV sources, MGRO J2019+37 and MGRO J2031+41, are analyzed using Milagro data with a new technique, and their emission is tested under two different spectral assumptions: a power law and a power law with an exponential cutoff. The new analysis technique is based on an energy estimator that uses the fraction of photomultiplier tubes in the observatory that detect the extensive air shower. The photon spectrum ismore » measured in the range 1-100 TeV using the last three years of Milagro data (2005-2008), with the detector in its final configuration. An F-test indicates that MGRO J2019+37 is better fit by a power law with an exponential cutoff than by a simple power law. The best-fitting parameters for the power law with exponential cutoff model are a normalization at 10 TeV of 7{sup +5}{sub -2} Multiplication-Sign 10{sup -10} s{sup -1} m{sup -2} TeV{sup -1}, a spectral index of 2.0{sup +0.5}{sub -1.0}, and a cutoff energy of 29{sup +50}{sub -16} TeV. MGRO J2031+41 shows no evidence of a cutoff. The best-fitting parameters for a power law are a normalization of 2.1{sup +0.6}{sub -0.6} Multiplication-Sign 10{sup -10} s{sup -1} m{sup -2} TeV{sup -1} and a spectral index of 3.22{sup +0.23}{sub -0.18}. The overall flux is subject to a {approx}30% systematic uncertainty. The systematic uncertainty on the power-law indices is {approx}0.1. Both uncertainties have been verified with cosmic-ray data. A comparison with previous results from TeV J2032+4130, MGRO J2031+41, and MGRO J2019+37 is also presented.« less

  3. Spectrum and Morphology of the Two Brightest Milagro Sources in the Cygnus Region: MGRO J2019+37 and MGRO J2031+41

    NASA Technical Reports Server (NTRS)

    Abdo, A. A.; Abeysekara, U.; Allen, B, T.; Aune, T.; Berley, D.; Bonamente, E.; Christopher, G. E.; DeYoung, T.; Dingus, B. L.; Ellsworth, R. W.; hide

    2012-01-01

    The Cygnus region is a very bright and complex portion of the TeV sky, host to unidentified sources and a diffuse excess with respect to conventional cosmic-ray propagation models. Two of the brightest TeV sources, MGRO J2019+37 and MGRO J2031+41, are analyzed using Milagro data with a new technique, and their emission is tested under two different spectral assumptions: a power law and a power law with an exponential cutoff. The new analysis technique is based on an energy estimator that uses the fraction of photomultiplier tubes in the observatory that detect the extensive air shower. The photon spectrum is measured in the range 1-100 TeV using the last three years of Milagro data (2005-2008), with the detector in its final configuration. An F-test indicates that MGRO J2019+37 is better fit by a power law with an exponential cutoff than by a simple power law. The best-fitting parameters for the power law with exponential cutoff model are a normalization at 10 TeV of 7(sup +5 sub -2) × 10(exp -10)/ s /sq m/ TeV, a spectral index of 2.0(sup +0.5 sub -10), and a cutoff energy of 29(sup +50 sub -16) TeV. MGRO J2031+41 shows no evidence of a cutoff. The best-fitting parameters for a power law are a normalization of 2.1(sup +0.6 sub -0.6) × 10(exp -10)/ s/sq m/ TeV and a spectral index of 3.22(sup +0.23 sub -0.18. The overall flux is subject to a approx.. 30% systematic uncertainty. The systematic uncertainty on the power-law indices is approx. 0.1. Both uncertainties have been verified with cosmic-ray data. A comparison with previous results from TeV J2032+4130, MGRO J2031+41, and MGRO J2019+37 is also presented.

  4. Spectrum and Morphology of the Two Brightest Milagro Sources in the Cygnus Region: MGRO J2019+37 and MGRO J2031+41

    NASA Astrophysics Data System (ADS)

    Abdo, A. A.; Abeysekara, U.; Allen, B. T.; Aune, T.; Berley, D.; Bonamente, E.; Christopher, G. E.; DeYoung, T.; Dingus, B. L.; Ellsworth, R. W.; Galbraith-Frew, J. G.; Gonzalez, M. M.; Goodman, J. A.; Hoffman, C. M.; Hüntemeyer, P. H.; Hui, C. M.; Kolterman, B. E.; Linnemann, J. T.; McEnery, J. E.; Mincer, A. I.; Morgan, T.; Nemethy, P.; Pretz, J.; Ryan, J. M.; Saz Parkinson, P. M.; Shoup, A.; Sinnis, G.; Smith, A. J.; Vasileiou, V.; Walker, G. P.; Williams, D. A.; Yodh, G. B.

    2012-07-01

    The Cygnus region is a very bright and complex portion of the TeV sky, host to unidentified sources and a diffuse excess with respect to conventional cosmic-ray propagation models. Two of the brightest TeV sources, MGRO J2019+37 and MGRO J2031+41, are analyzed using Milagro data with a new technique, and their emission is tested under two different spectral assumptions: a power law and a power law with an exponential cutoff. The new analysis technique is based on an energy estimator that uses the fraction of photomultiplier tubes in the observatory that detect the extensive air shower. The photon spectrum is measured in the range 1-100 TeV using the last three years of Milagro data (2005-2008), with the detector in its final configuration. An F-test indicates that MGRO J2019+37 is better fit by a power law with an exponential cutoff than by a simple power law. The best-fitting parameters for the power law with exponential cutoff model are a normalization at 10 TeV of 7+5 -2 × 10-10 s-1 m-2 TeV-1, a spectral index of 2.0+0.5 -1.0, and a cutoff energy of 29+50 -16 TeV. MGRO J2031+41 shows no evidence of a cutoff. The best-fitting parameters for a power law are a normalization of 2.1+0.6 -0.6 × 10-10 s-1 m-2 TeV-1 and a spectral index of 3.22+0.23 -0.18. The overall flux is subject to a ~30% systematic uncertainty. The systematic uncertainty on the power-law indices is ~0.1. Both uncertainties have been verified with cosmic-ray data. A comparison with previous results from TeV J2032+4130, MGRO J2031+41, and MGRO J2019+37 is also presented.

  5. Experimental progressive emphysema in BALB/cJ mice as a model for chronic alveolar destruction in humans

    PubMed Central

    Limjunyawong, Nathachit; Craig, John M.; Lagassé, H. A. Daniel; Scott, Alan L.

    2015-01-01

    Emphysema, one of the major components of chronic obstructive pulmonary disease (COPD), is characterized by the progressive and irreversible loss of alveolar lung tissue. Even though >80% of COPD cases are associated with cigarette smoking, only a relatively small proportion of smokers develop emphysema, suggesting a potential role for genetic factors in determining individual susceptibility to emphysema. Although strain-dependent effects have been shown in animal models of emphysema, the molecular basis underlying this intrinsic susceptibility is not fully understood. In this present study, we investigated emphysema development using the elastase-induced experimental emphysema model in two commonly used mouse strains, C57BL/6J and BALB/cJ. The results demonstrate that mice with different genetic backgrounds show disparate susceptibility to the development of emphysema. BALB/cJ mice were found to be much more sensitive than C57BL/6J to elastase injury in both a dose-dependent and time-dependent manner, as measured by significantly higher mortality, greater body weight loss, greater decline in lung function, and a greater loss of alveolar tissue. The more susceptible BALB/cJ strain also showed the persistence of inflammatory cells in the lung, especially macrophages and lymphocytes. A comparative gene expression analysis following elastase-induced injury showed BALB/cJ mice had elevated levels of il17A mRNA and a number of classically (M1) and alternatively (M2) activated macrophage genes, whereas the C57BL/6J mice demonstrated augmented levels of interferon-γ. These findings suggest a possible role for these cellular and molecular mediators in modulating the severity of emphysema and highlight the possibility that they might contribute to the heterogeneity observed in clinical emphysema outcomes. PMID:26232300

  6. Experimental progressive emphysema in BALB/cJ mice as a model for chronic alveolar destruction in humans.

    PubMed

    Limjunyawong, Nathachit; Craig, John M; Lagassé, H A Daniel; Scott, Alan L; Mitzner, Wayne

    2015-10-01

    Emphysema, one of the major components of chronic obstructive pulmonary disease (COPD), is characterized by the progressive and irreversible loss of alveolar lung tissue. Even though >80% of COPD cases are associated with cigarette smoking, only a relatively small proportion of smokers develop emphysema, suggesting a potential role for genetic factors in determining individual susceptibility to emphysema. Although strain-dependent effects have been shown in animal models of emphysema, the molecular basis underlying this intrinsic susceptibility is not fully understood. In this present study, we investigated emphysema development using the elastase-induced experimental emphysema model in two commonly used mouse strains, C57BL/6J and BALB/cJ. The results demonstrate that mice with different genetic backgrounds show disparate susceptibility to the development of emphysema. BALB/cJ mice were found to be much more sensitive than C57BL/6J to elastase injury in both a dose-dependent and time-dependent manner, as measured by significantly higher mortality, greater body weight loss, greater decline in lung function, and a greater loss of alveolar tissue. The more susceptible BALB/cJ strain also showed the persistence of inflammatory cells in the lung, especially macrophages and lymphocytes. A comparative gene expression analysis following elastase-induced injury showed BALB/cJ mice had elevated levels of il17A mRNA and a number of classically (M1) and alternatively (M2) activated macrophage genes, whereas the C57BL/6J mice demonstrated augmented levels of interferon-γ. These findings suggest a possible role for these cellular and molecular mediators in modulating the severity of emphysema and highlight the possibility that they might contribute to the heterogeneity observed in clinical emphysema outcomes. Copyright © 2015 the American Physiological Society.

  7. Validity Assessment of 5 Day Repeated Forced-Swim Stress to Model Human Depression in Young-Adult C57BL/6J and BALB/cJ Mice.

    PubMed

    Mul, Joram D; Zheng, Jia; Goodyear, Laurie J

    2016-01-01

    The development of animal models with construct, face, and predictive validity to accurately model human depression has been a major challenge. One proposed rodent model is the 5 d repeated forced swim stress (5d-RFSS) paradigm, which progressively increases floating during individual swim sessions. The onset and persistence of this floating behavior has been anthropomorphically characterized as a measure of depression. This interpretation has been under debate because a progressive increase in floating over time may reflect an adaptive learned behavioral response promoting survival, and not depression (Molendijk and de Kloet, 2015). To assess construct and face validity, we applied 5d-RFSS to C57BL/6J and BALB/cJ mice, two mouse strains commonly used in neuropsychiatric research, and measured a combination of emotional, homeostatic, and psychomotor symptoms indicative of a depressive-like state. We also compared the efficacy of 5d-RFSS and chronic social defeat stress (CSDS), a validated depression model, to induce a depressive-like state in C57BL/6J mice. In both strains, 5d-RFSS progressively increased floating behavior that persisted for at least 4 weeks. 5d-RFSS did not alter sucrose preference, body weight, appetite, locomotor activity, anxiety-like behavior, or immobility behavior during a tail-suspension test compared with nonstressed controls. In contrast, CSDS altered several of these parameters, suggesting a depressive-like state. Finally, predictive validity was assessed using voluntary wheel running (VWR), a known antidepressant intervention. Four weeks of VWR after 5d-RFSS normalized floating behavior toward nonstressed levels. These observations suggest that 5d-RFSS has no construct or face validity but might have predictive validity to model human depression.

  8. Models of the strongly lensed quasar DES J0408-5354

    NASA Astrophysics Data System (ADS)

    Agnello, A.; Lin, H.; Buckley-Geer, L.; Treu, T.; Bonvin, V.; Courbin, F.; Lemon, C.; Morishita, T.; Amara, A.; Auger, M. W.; Birrer, S.; Chan, J.; Collett, T.; More, A.; Fassnacht, C. D.; Frieman, J.; Marshall, P. J.; McMahon, R. G.; Meylan, G.; Suyu, S. H.; Castander, F.; Finley, D.; Howell, A.; Kochanek, C.; Makler, M.; Martini, P.; Morgan, N.; Nord, B.; Ostrovski, F.; Schechter, P.; Tucker, D.; Wechsler, R.; Abbott, T. M. C.; Abdalla, F. B.; Allam, S.; Benoit-Lévy, A.; Bertin, E.; Brooks, D.; Burke, D. L.; Rosell, A. Carnero; Kind, M. Carrasco; Carretero, J.; Crocce, M.; Cunha, C. E.; D'Andrea, C. B.; da Costa, L. N.; Desai, S.; Dietrich, J. P.; Eifler, T. F.; Flaugher, B.; Fosalba, P.; García-Bellido, J.; Gaztanaga, E.; Gill, M. S.; Goldstein, D. A.; Gruen, D.; Gruendl, R. A.; Gschwend, J.; Gutierrez, G.; Honscheid, K.; James, D. J.; Kuehn, K.; Kuropatkin, N.; Li, T. S.; Lima, M.; Maia, M. A. G.; March, M.; Marshall, J. L.; Melchior, P.; Menanteau, F.; Miquel, R.; Ogando, R. L. C.; Plazas, A. A.; Romer, A. K.; Sanchez, E.; Schindler, R.; Schubnell, M.; Sevilla-Noarbe, I.; Smith, M.; Smith, R. C.; Sobreira, F.; Suchyta, E.; Swanson, M. E. C.; Tarle, G.; Thomas, D.; Walker, A. R.

    2017-12-01

    We present detailed modelling of the recently discovered, quadruply lensed quasar J0408-5354, with the aim of interpreting its remarkable configuration: besides three quasar images (A,B,D) around the main deflector (G1), a fourth image (C) is significantly reddened and dimmed by a perturber (G2) which is not detected in the Dark Energy Survey imaging data. From lens models incorporating (dust-corrected) flux ratios, we find a perturber Einstein radius 0.04 arcsec ≲ RE, G2 ≲ 0.2 arcsec and enclosed mass Mp(RE, G2) ≲ 1.0 × 1010 M⊙. The main deflector has stellar mass log _{10}(M_{\\star }/M_{⊙})=11.49^{+0.46}_{-0.32}, a projected mass Mp(RE, G1) ≈ 6 × 1011 M⊙ within its Einstein radius RE, G1 = (1.85 ± 0.15) arcsec and predicted velocity dispersion 267-280 km s-1. Follow-up images from a companion monitoring campaign show additional components, including a candidate second source at a redshift between the quasar and G1. Models with free perturbers, and dust-corrected and delay-corrected flux ratios, are also explored. The predicted time-delays (ΔtAB = (135.0 ± 12.6) d, ΔtBD = (21.0 ± 3.5) d) roughly agree with those measured, but better imaging is required for proper modelling and comparison. We also discuss some lessons learnt from J0408-5354 on lensed quasar finding strategies, due to its chromaticity and morphology.

  9. jà Vu: An Illusion of Prediction.

    PubMed

    Cleary, Anne M; Claxton, Alexander B

    2018-04-01

    jà vu is beginning to be scientifically understood as a memory phenomenon. Despite recent scientific advances, a remaining puzzle is the purported association between déjà vu and feelings of premonition. Building on research showing that déjà vu can be driven by an unrecalled memory of a past experience that relates to the current situation, we sought evidence of memory-based predictive ability during déjà vu states. Déjà vu did not lead to above-chance ability to predict the next turn in a navigational path resembling a previously experienced but unrecalled path (although such resemblance increased reports of déjà vu). However, déjà vu states were accompanied by increased feelings of knowing the direction of the next turn. The results suggest that feelings of premonition during déjà vu occur and can be illusory. Metacognitive bias brought on by the state itself may explain the peculiar association between déjà vu and the feeling of premonition.

  10. Repeatability analysis of the K. J. Law Model 8300 Roughness Surveyor : final report.

    DOT National Transportation Integrated Search

    1991-04-01

    The K.J. Law Model 8300 Roughness surveyor, is a ride-quality measurement device used to determine and analyze the longitudinal roadway profile. This paper describes an analysis of IRI data as collected with Louisiana's Roughness Surveyor to determin...

  11. Observation of J/ψϕ Structures Consistent with Exotic States from Amplitude Analysis of B^{+}→J/ψϕK^{+} Decays.

    PubMed

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Rodriguez Perez, P; Rogozhnikov, A; Roiser, S; Romanovskiy, V; Romero Vidal, A; Ronayne, J W; Rotondo, M; Ruf, T; Ruiz Valls, P; Saborido Silva, J J; Sadykhov, E; Sagidova, N; Saitta, B; Salustino Guimaraes, V; Sanchez Mayordomo, C; Sanmartin Sedes, B; Santacesaria, R; Santamarina Rios, C; Santimaria, M; Santovetti, E; Sarti, A; Satriano, C; Satta, A; Saunders, D M; Savrina, D; Schael, S; Schellenberg, M; Schiller, M; Schindler, H; Schlupp, M; Schmelling, M; Schmelzer, T; Schmidt, B; Schneider, O; Schopper, A; Schubert, K; Schubiger, M; Schune, M-H; Schwemmer, R; Sciascia, B; Sciubba, A; Semennikov, A; Sergi, A; Serra, N; Serrano, J; Sestini, L; Seyfert, P; Shapkin, M; Shapoval, I; Shcheglov, Y; Shears, T; Shekhtman, L; Shevchenko, V; Shires, A; Siddi, B G; Silva Coutinho, R; Silva de Oliveira, L; Simi, G; Simone, S; Sirendi, M; Skidmore, N; Skwarnicki, T; Smith, E; Smith, I T; Smith, J; Smith, M; Snoek, H; Sokoloff, M D; Soler, F J P; Souza, D; Souza De Paula, B; Spaan, B; Spradlin, P; Sridharan, S; Stagni, F; Stahl, M; Stahl, S; Stefko, P; Stefkova, S; Steinkamp, O; Stenyakin, O; Stevenson, S; Stoica, S; Stone, S; Storaci, B; Stracka, S; Straticiuc, M; Straumann, U; Sun, L; Sutcliffe, W; Swientek, K; Syropoulos, V; Szczekowski, M; Szumlak, T; T'Jampens, S; Tayduganov, A; Tekampe, T; Tellarini, G; Teubert, F; Thomas, C; Thomas, E; van Tilburg, J; Tisserand, V; Tobin, M; Tolk, S; Tomassetti, L; Tonelli, D; Topp-Joergensen, S; Toriello, F; Tournefier, E; Tourneur, S; Trabelsi, K; Traill, M; Tran, M T; Tresch, M; Trisovic, A; Tsaregorodtsev, A; Tsopelas, P; Tully, A; Tuning, N; Ukleja, A; Ustyuzhanin, A; Uwer, U; Vacca, C; Vagnoni, V; Valat, S; Valenti, G; Vallier, A; Vazquez Gomez, R; Vazquez Regueiro, P; Vecchi, S; van Veghel, M; Velthuis, J J; Veltri, M; Veneziano, G; Venkateswaran, A; Vernet, M; Vesterinen, M; Viaud, B; Vieira, D; Vieites Diaz, M; Vilasis-Cardona, X; Volkov, V; Vollhardt, A; Voneki, B; Voong, D; Vorobyev, A; Vorobyev, V; Voß, C; de Vries, J A; Vázquez Sierra, C; Waldi, R; Wallace, C; Wallace, R; Walsh, J; Wang, J; Ward, D R; Wark, H M; Watson, N K; Websdale, D; Weiden, A; Whitehead, M; Wicht, J; Wilkinson, G; Wilkinson, M; Williams, M; Williams, M P; Williams, M; Williams, T; Wilson, F F; Wimberley, J; Wishahi, J; Wislicki, W; Witek, M; Wormser, G; Wotton, S A; Wraight, K; Wright, S; Wyllie, K; Xie, Y; Xing, Z; Xu, Z; Yang, Z; Yin, H; Yu, J; Yuan, X; Yushchenko, O; Zangoli, M; Zarebski, K A; Zavertyaev, M; Zhang, L; Zhang, Y; Zhang, Y; Zhelezov, A; Zheng, Y; Zhokhov, A; Zhukov, V; Zucchelli, S

    2017-01-13

    The first full amplitude analysis of B^{+}→J/ψϕK^{+} with J/ψ→μ^{+}μ^{-}, ϕ→K^{+}K^{-} decays is performed with a data sample of 3  fb^{-1} of pp collision data collected at sqrt[s]=7 and 8 TeV with the LHCb detector. The data cannot be described by a model that contains only excited kaon states decaying into ϕK^{+}, and four J/ψϕ structures are observed, each with significance over 5 standard deviations. The quantum numbers of these structures are determined with significance of at least 4 standard deviations. The lightest has mass consistent with, but width much larger than, previous measurements of the claimed X(4140) state.

  12. Observation of J/psi-->3gamma.

    PubMed

    Adams, G S; Anderson, M; Cummings, J P; Danko, I; Hu, D; Moziak, B; Napolitano, J; He, Q; Insler, J; Muramatsu, H; Park, C S; Thorndike, E H; Yang, F; Artuso, M; Blusk, S; Khalil, S; Li, J; Mountain, R; Nisar, S; Randrianarivony, K; Sultana, N; Skwarnicki, T; Stone, S; Wang, J C; Zhang, L M; Bonvicini, G; Cinabro, D; Dubrovin, M; Lincoln, A; Naik, P; Rademacker, J; Asner, D M; Edwards, K W; Reed, J; Briere, R A; Ferguson, T; Ma, J S Y; Tatishvili, G; Vogel, H; Watkins, M E; Rosner, J L; Alexander, J P; Cassel, D G; Duboscq, J E; Ehrlich, R; Fields, L; Galik, R S; Gibbons, L; Gray, R; Gray, S W; Hartill, D L; Heltsley, B K; Hertz, D; Hunt, J M; Kandaswamy, J; Kreinick, D L; Kuznetsov, V E; Ledoux, J; Mahlke-Krüger, H; Mohapatra, D; Onyisi, P U E; Patterson, J R; Peterson, D; Riley, D; Ryd, A; Sadoff, A J; Shi, X; Stroiney, S; Sun, W M; Wilksen, T; Athar, S B; Patel, R; Yelton, J; Rubin, P; Eisenstein, B I; Karliner, I; Mehrabyan, S; Lowrey, N; Selen, M; White, E J; Wiss, J; Mitchell, R E; Shepherd, M R; Besson, D; Pedlar, T K; Cronin-Hennessy, D; Gao, K Y; Hietala, J; Kubota, Y; Klein, T; Lang, B W; Poling, R; Scott, A W; Zweber, P; Dobbs, S; Metreveli, Z; Seth, K K; Tomaradze, A; Libby, J; Powell, A; Wilkinson, G; Ecklund, K M; Love, W; Savinov, V; Mendez, H; Ge, J Y; Miller, D H; Shipsey, I P J; Xin, B

    2008-09-05

    We report the first observation of the decay J/psi-->3gamma. The signal has a statistical significance of 6sigma and corresponds to a branching fraction of B(J/psi-->3gamma)=(1.2+/-0.3+/-0.2)x10;{-5}, in which the errors are statistical and systematic, respectively. The measurement uses psi(2S)-->pi;{+}pi;{-}J/psi events acquired with the CLEO-c detector operating at the CESR e;{+}e;{-} collider.

  13. Phenotypic instability between the near isogenic substrains BALB/cJ and BALB/cByJ.

    PubMed

    Sittig, Laura J; Jeong, Choongwon; Tixier, Emily; Davis, Joe; Barrios-Camacho, Camila M; Palmer, Abraham A

    2014-12-01

    Closely related substrains of inbred mice often show phenotypic differences that are presumed to be caused by recent mutations. The substrains BALB/cJ and BALB/cByJ, which were separated in 1935, have been reported to show numerous highly significant behavioral and morphological differences. In an effort to identify some of the causal mutations, we phenotyped BALB/cJ and BALB/cByJ mice as well as their F1, F2, and N2 progeny for behavioral and morphological phenotypes. We also generated whole-genome sequence data for both inbred strains (~3.5× coverage) with the intention of identifying polymorphic markers to be used for linkage analysis. We observed significant differences in body weight, the weight of the heart, liver, spleen and brain, and corpus callosum length between the two substrains. We also observed that BALB/cJ animals showed greater anxiety-like behavior in the open field test, less depression-like behavior in the tail suspension test, and reduced aggression compared to BALB/cByJ mice. Some but not all of these physiological and behavioral results were inconsistent with prior publications. These inconsistencies led us to suspect that the differences were due to, or modified by, non-genetic factors. Thus, we did not perform linkage analysis. We provide a comprehensive summary of the prior literature about phenotypic differences between these substrains as well as our current findings. We conclude that many differences between these strains are unstable and therefore ill-suited to linkage analysis; the source of this instability is unclear. We discuss the broader implications of these observations for the design of future studies.

  14. Phenotypic instability between the near isogenic substrains BALB/cJ and BALB/cByJ

    PubMed Central

    Sittig, Laura J.; Jeong, Choongwon; Tixier, Emily; Davis, Joe; Barrios Camacho, Camila M.; Palmer, Abraham A.

    2014-01-01

    Closely related substrains of inbred mice often show phenotypic difzferences that are presumed to be caused by recent mutations. The substrains BALB/cJ and BALB/cByJ, which were separated in 1935, have been reported to show numerous highly significant behavioral and morphological differences. In an effort to identify some of the causal mutations, we phenotyped BALB/cJ and BALB/cByJ mice as well as their F1, F2, and N2 progeny for behavioral and morphological phenotypes. We also generated whole genome sequence data for both inbred strains (∼3.5× coverage) with the intention of identifying polymorphic markers to be used for linkage analysis. We observed significant differences in body weight, the weight of the heart, liver, spleen and brain, and corpus callosum length between the two substrains. We also observed that BALB/cJ animals showed greater anxiety-like behavior in the open field test, less depression-like behavior in the tail suspension test, and reduced aggression compared to BALB/cByJ mice. Some but not all of these physiological and behavioral results were inconsistent with prior publications. These inconsistencies led us to suspect that the differences were due to, or modified by, non-genetic factors. Thus, we did not perform linkage analysis. We provide a comprehensive summary of the prior literature about phenotypic differences between these substrains as well as our current findings. We conclude that many differences between these strains are unstable and therefore ill-suited to linkage analysis; the source of this instability is unclear. We discuss the broader implications of these observations for the design of future studies. PMID:24997021

  15. Hemoglobin J-Korat in Thais.

    PubMed

    Blackwell, R Q; Blackwell, B N; Huang, J T; Chien, L C; Samaharn, A; Thephusdin, C; Borvornsin, C

    1965-12-17

    Hemoglobin J(Korat), a "fast" hemoglobin with an anomaly in its beta chain different from the anomalies previously reported, was the major hemoglobin component in the blood of nine subjects among 1923 Thais from northeastern Thailand. After hemoglobin E, J(Korat) is the second most frequent of the anomalous hemoglobins among Thais.

  16. J-2X powerpack

    NASA Image and Video Library

    2012-10-05

    NASA removed J-2X engine No. 10001 from the A-2 Test Stand at Stennis Space Center in early October. Opening of the test stand clamshell flooring allowed a clear view of the next-generation engine and stub nozzle, which is being built to help power future deep-space missions. The engine is an upgrade from the heritage J-2 rocket engine, which helped power Apollo missions to the moon during the late 1960s and early 1970s.

  17. Multiple Quantum Coherences (MQ) NMR and Entanglement Dynamics in the Mixed-Three-Spin XXX Heisenberg Model with Single-Ion Anisotropy

    NASA Astrophysics Data System (ADS)

    Hamid, Arian Zad

    2016-12-01

    We analytically investigate Multiple Quantum (MQ) NMR dynamics in a mixed-three-spin (1/2,1,1/2) system with XXX Heisenberg model at the front of an external homogeneous magnetic field B. A single-ion anisotropy property ζ is considered for the spin-1. The intensities dependence of MQ NMR coherences on their orders (zeroth and second orders) for two pairs of spins (1,1/2) and (1/2,1/2) of the favorite tripartite system are obtained. It is also investigated dynamics of the pairwise quantum entanglement for the bipartite (sub)systems (1,1/2) and (1/2,1/2) permanently coupled by, respectively, coupling constants J}1 and J}2, by means of concurrence and fidelity. Then, some straightforward comparisons are done between these quantities and the intensities of MQ NMR coherences and ultimately some interesting results are reported. We also show that the time evolution of MQ coherences based on the reduced density matrix of the pair spins (1,1/2) is closely connected with the dynamics of the pairwise entanglement. Finally, we prove that one can introduce MQ coherence of the zeroth order corresponds to the pair spins (1,1/2) as an entanglement witness at some special time intervals.

  18. Quantum phases of dimerized and frustrated Heisenberg spin chains with s = 1/2, 1 and 3/2: an entanglement entropy and fidelity study.

    PubMed

    Goli, V M L Durga Prasad; Sahoo, Shaon; Ramasesha, S; Sen, Diptiman

    2013-03-27

    We study here different regions in phase diagrams of the spin-1/2, spin-1 and spin-3/2 one-dimensional antiferromagnetic Heisenberg systems with frustration (next-nearest-neighbor interaction J2) and dimerization (δ). In particular, we analyze the behaviors of the bipartite entanglement entropy and fidelity at the gapless to gapped phase transitions and across the lines separating different phases in the J2-δ plane. All the calculations in this work are based on numerical exact diagonalizations of finite systems.

  19. Two American Entrepreneurs: Madame C. J. Walker and J. C. Penney. Teaching with Historic Places.

    ERIC Educational Resources Information Center

    Koman, Rita

    2000-01-01

    This lesson is based on the National Historic Landmark files, "Madame C. J. Walker Building" and "J. C. Penney Historic District," as well as other relevant sources. The lesson first discusses the Indianapolis (Indiana) site of Madame Walker's cosmetics business. The building is a 4-story brick structure completed in 1927.…

  20. Cholesterol kinetic effects of dietary fat in CBA/J and C57BR/cdJ mice

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stewart, J.; Kuan, Soniu; Seagrave, R.

    1990-02-26

    Small differences in dietary fats cause marked differences in cholesterol metabolism in different strains of mice. CBA/J mice adjust HMGCOA reductase activity and C57BR/cdJ mice change fecal excretion of cholesterol. Phenomenological compartmental modeling of movement of 4{sup 14}C-cholesterol in the two strains of mice fed 40 en % fat, P/S = 0.24 (SFA) or 30 en % fat, P/S = 1 (PUFA) was used to analyze rates of movement between serum, liver, heart, and carcass. The C57 mice had slower movement between all compartments than CBA. Residence times in tissues were longer in mice fed SFA than those fed PUFAmore » diet. The kinetic results are in agreement with the organ concentrations and enzyme activities measured.« less

  1. Renovation of HEPnet-J for near-future experiments

    NASA Astrophysics Data System (ADS)

    Suzuki, Soh Y.; Yuasa, Fukuko; Nakamura, Tomoaki; Hara, Takanori

    2015-12-01

    Originally HEPnet-J had only one instance that is connected to Internet as the network connectivity by campus network of institutes in Japan was very limited, so the main purpose of HEPnet-J was providing enough connectivity for interactive use on domestic and international links funded by KEK. In last 10 years, the domestic and international connectivity provided by NRENs have been dramatically improved and they are enough for manual transfer of typical skimmed data files. Therefore, HEPnet-J has many closed networks that connect domestic sites related to specific projects, in order to access them on computer farms in private networks in their home institutes. The rapid growth of data volume makes it unable to apply same model to new generation experiments. As the tier structure for LHC computing sites has proved that the distributed computing model over collaboration sites is really applicable to the huge scale experiment, the external connectivity for international collaboration sites should be faster and secure. For example, the Belle II experiment in KEK will have many repositories in U.S. and EU. The expected throughput from KEK to U.S. is about 20 Gbps, thus it need the bypass of slow security devices like a firewall. Now bypass lines for Belle II are prepared and under tasting. This article reports the brief history of HEPnet- J and recent changes for project-specific networks.

  2. Testing for the J-2X Upper Stage Engine

    NASA Technical Reports Server (NTRS)

    Buzzell, James C.

    2010-01-01

    NASA selected the J-2X Upper Stage Engine in 2006 to power the upper stages of the Ares I crew launch vehicle and the Ares V cargo launch vehicle. Based on the proven Saturn J-2 engine, this new engine will provide 294,000 pounds of thrust and a specific impulse of 448 seconds, making it the most efficient gas generator cycle engine in history. The engine's guiding philosophy emerged from the Exploration Systems Architecture Study (ESAS) in 2005. Goals established then called for vehicles and components based, where feasible, on proven hardware from the Space Shuttle, commercial, and other programs, to perform the mission and provide an order of magnitude greater safety. Since that time, the team has made unprecedented progress. Ahead of the other elements of the Constellation Program architecture, the team has progressed through System Requirements Review (SRR), System Design Review (SDR), Preliminary Design Review (PDR), and Critical Design Review (CDR). As of February 2010, more than 100,000 development engine parts have been ordered and more than 18,000 delivered. Approximately 1,300 of more than 1,600 engine drawings were released for manufacturing. A major factor in the J-2X development approach to this point is testing operations of heritage J-2 engine hardware and new J-2X components to understand heritage performance, validate computer modeling of development components, mitigate risk early in development, and inform design trades. This testing has been performed both by NASA and its J-2X prime contractor, Pratt & Whitney Rocketdyne (PWR). This body of work increases the likelihood of success as the team prepares for testing the J-2X powerpack and first development engine in calendar 2011. This paper will provide highlights of J-2X testing operations, engine test facilities, development hardware, and plans.

  3. J / ψ Production and Polarization within a Jet

    DOE PAGES

    Kang, Zhong-Bo; Qiu, Jian-Wei; Ringer, Felix; ...

    2017-07-18

    We study the production and polarization of J/Ψ mesons within a jet in proton-proton collisions at the LHC. Here, we define the J/Ψ-jet fragmentation function as a ratio of differential jet cross sections with and without the reconstructed J/Ψ in the jet. We also demonstrate that this is a very useful observable to help explore the J/Ψ production mechanism, and to differentiate between different NRQCD global fits based on inclusive J/Ψ cross sections. Moreover, we propose to measure the polarization of J/Ψ mesons inside the jet, which can provide even more stringent constraints for the heavy quarkonium production mechanism.

  4. J / ψ Production and Polarization within a Jet

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kang, Zhong-Bo; Qiu, Jian-Wei; Ringer, Felix

    We study the production and polarization of J/Ψ mesons within a jet in proton-proton collisions at the LHC. Here, we define the J/Ψ-jet fragmentation function as a ratio of differential jet cross sections with and without the reconstructed J/Ψ in the jet. We also demonstrate that this is a very useful observable to help explore the J/Ψ production mechanism, and to differentiate between different NRQCD global fits based on inclusive J/Ψ cross sections. Moreover, we propose to measure the polarization of J/Ψ mesons inside the jet, which can provide even more stringent constraints for the heavy quarkonium production mechanism.

  5. Ribonucleases J1 and J2: two novel endoribonucleases in B.subtilis with functional homology to E.coli RNase E

    PubMed Central

    Even, Sergine; Pellegrini, Olivier; Zig, Lena; Labas, Valerie; Vinh, Joelle; Bréchemmier-Baey, Dominique; Putzer, Harald

    2005-01-01

    Many prokaryotic organisms lack an equivalent of RNase E, which plays a key role in mRNA degradation in Escherichia coli. In this paper, we report the purification and identification by mass spectrometry in Bacillus subtilis of two paralogous endoribonucleases, here named RNases J1 and J2, which share functional homologies with RNase E but no sequence similarity. Both enzymes are able to cleave the B.subtilis thrS leader at a site that can also be cleaved by E.coli RNase E. We have previously shown that cleavage at this site increases the stability of the downstream messenger. Moreover, RNases J1/J2 are sensitive to the 5′ phosphorylation state of the substrate in a site-specific manner. Orthologues of RNases J1/J2, which belong to the metallo-β-lactamase family, are evolutionarily conserved in many prokaryotic organisms, representing a new family of endoribonucleases. RNases J1/J2 appear to be implicated in regulatory processing/maturation of specific mRNAs, such as the T-box family members thrS and thrZ, but may also contribute to global mRNA degradation. PMID:15831787

  6. SoilJ - An ImageJ plugin for semi-automatized image-processing of 3-D X-ray images of soil columns

    NASA Astrophysics Data System (ADS)

    Koestel, John

    2016-04-01

    3-D X-ray imaging is a formidable tool for quantifying soil structural properties which are known to be extremely diverse. This diversity necessitates the collection of large sample sizes for adequately representing the spatial variability of soil structure at a specific sampling site. One important bottleneck of using X-ray imaging is however the large amount of time required by a trained specialist to process the image data which makes it difficult to process larger amounts of samples. The software SoilJ aims at removing this bottleneck by automatizing most of the required image processing steps needed to analyze image data of cylindrical soil columns. SoilJ is a plugin of the free Java-based image-processing software ImageJ. The plugin is designed to automatically process all images located with a designated folder. In a first step, SoilJ recognizes the outlines of the soil column upon which the column is rotated to an upright position and placed in the center of the canvas. Excess canvas is removed from the images. Then, SoilJ samples the grey values of the column material as well as the surrounding air in Z-direction. Assuming that the column material (mostly PVC of aluminium) exhibits a spatially constant density, these grey values serve as a proxy for the image illumination at a specific Z-coordinate. Together with the grey values of the air they are used to correct image illumination fluctuations which often occur along the axis of rotation during image acquisition. SoilJ includes also an algorithm for beam-hardening artefact removal and extended image segmentation options. Finally, SoilJ integrates the morphology analyses plugins of BoneJ (Doube et al., 2006, BoneJ Free and extensible bone image analysis in ImageJ. Bone 47: 1076-1079) and provides an ASCII file summarizing these measures for each investigated soil column, respectively. In the future it is planned to integrate SoilJ into FIJI, the maintained and updated edition of ImageJ with selected

  7. The Natural Selection of the Chemical Elements (by R. J. P. Williams and J. J. R. Fraústo da Silva)

    NASA Astrophysics Data System (ADS)

    Kauffman, George B.

    1998-12-01

    Clarendon: New York, 1996. xxvi + 646 pp. Figs., tables. 20.5 x 25.6 cm. ISBN 0-19-855843-0. $80.00. R. J. P. Williams, Royal Society Research Professor Emeritus at Wadham College, Oxford University, and J. J. R. Fraústo da Silva, Professor of Analytical Chemistry at the Instituto Superior Técnico, Universidade Técnica de Lisboa, have collaborated on two previous volumes: New Trends in Bio-inorganic Chemistry (1978) and The Biological Chemistry of the Elements (3rd printing, 1994). Their latest collaborative effort is a book whose ambitious objective is "to show the relationship of every kind of material around us, living and nonliving, to the properties of the chemical elements of the periodic table." The "natural selection" of the chemical elements results from a number of factors, all of which are described in detail. Among these are chemical affinity related to the electronic configuration of their atoms, thermodynamic and kinetic stability, and "functional value to an organisation such as a living system". The physicist's approach to material through phase structure and the phase rule is stressed rather than the chemist's approach through bonding theories. The entire book possesses a strong environmental and interdisciplinary emphasis.

  8. Validity Assessment of 5 Day Repeated Forced-Swim Stress to Model Human Depression in Young-Adult C57BL/6J and BALB/cJ Mice

    PubMed Central

    Zheng, Jia; Goodyear, Laurie J.

    2016-01-01

    The development of animal models with construct, face, and predictive validity to accurately model human depression has been a major challenge. One proposed rodent model is the 5 d repeated forced swim stress (5d-RFSS) paradigm, which progressively increases floating during individual swim sessions. The onset and persistence of this floating behavior has been anthropomorphically characterized as a measure of depression. This interpretation has been under debate because a progressive increase in floating over time may reflect an adaptive learned behavioral response promoting survival, and not depression (Molendijk and de Kloet, 2015). To assess construct and face validity, we applied 5d-RFSS to C57BL/6J and BALB/cJ mice, two mouse strains commonly used in neuropsychiatric research, and measured a combination of emotional, homeostatic, and psychomotor symptoms indicative of a depressive-like state. We also compared the efficacy of 5d-RFSS and chronic social defeat stress (CSDS), a validated depression model, to induce a depressive-like state in C57BL/6J mice. In both strains, 5d-RFSS progressively increased floating behavior that persisted for at least 4 weeks. 5d-RFSS did not alter sucrose preference, body weight, appetite, locomotor activity, anxiety-like behavior, or immobility behavior during a tail-suspension test compared with nonstressed controls. In contrast, CSDS altered several of these parameters, suggesting a depressive-like state. Finally, predictive validity was assessed using voluntary wheel running (VWR), a known antidepressant intervention. Four weeks of VWR after 5d-RFSS normalized floating behavior toward nonstressed levels. These observations suggest that 5d-RFSS has no construct or face validity but might have predictive validity to model human depression. PMID:28058270

  9. The origin of RX J1856.5-3754 and RX J0720.4-3125 - updated using new parallax measurements

    NASA Astrophysics Data System (ADS)

    Tetzlaff, N.; Eisenbeiss, T.; Neuhäuser, R.; Hohle, M. M.

    2011-10-01

    RX J1856.5-3754 and RX J0720.4-3125 are the only young isolated radio-quiet neutron stars (NSs) for which trigonometric parallaxes were measured. Due to detection of their thermal emission in X-rays, they are important to study NS cooling and to probe theoretical cooling models. Hence, a precise determination of their age is essential. Recently, new parallax measurements of RX J1856.5-3754 and RX J0720.4-3125 were obtained. Considering that NSs may originate from binary systems that got disrupted due to an asymmetric supernova, we attempt to identify runaway stars which may have been former companions to the NS progenitors. Such an identification would strongly support a particular birth scenario with time and place. We trace back each NS, runaway star and the centres of possible birth associations (assuming that most NSs are ejected directly from their parent association) to find close encounters. The kinematic age is then given by the time since the encounter. We use Monte Carlo simulations to account for observational uncertainties and evaluate the outcome statistically. Using the most recent parallax measurement of 8.16 ± 0.80 mas for RX J1856.5-3754 by Walter et al., we find that it originated in the Upper Scorpius association 0.46 ± 0.05 Myr ago. This kinematic age is slightly larger than the value we reported earlier (0.3 Myr) using the old parallax value of 5.6 ± 0.6 mas by Kaplan. Our result is strongly supported by its current radial velocity which we predict to be 6+19- 20 km s-1. This implies an inclination angle to the line of sight of 88°± 6° consistent with estimates by van Kerkwijk & Kulkarni from the bow shock. No suitable runaway star was found to be a potential former companion of RX J1856.5-3754. Making use of a recent parallax measurement for RX J0720.4-3125 of 3.6 ± 1.6 mas by Eisenbeiss, we find that this NS was possibly born in Trumpler 10 0.85 ± 0.15 Myr ago. This kinematic age is somewhat larger than the one obtained using the old

  10. Measurement of the Ratio of Branching Fractions B(B_{c}^{+}→J/ψτ^{+}ν_{τ})/B(B_{c}^{+}→J/ψμ^{+}ν_{μ}).

    PubMed

    Aaij, R; Adeva, B; Adinolfi, M; Ajaltouni, Z; Akar, S; Albrecht, J; Alessio, F; Alexander, M; Alfonso Albero, A; Ali, S; Alkhazov, G; Alvarez Cartelle, P; Alves, A A; Amato, S; Amerio, S; Amhis, Y; An, L; Anderlini, L; Andreassi, G; Andreotti, M; Andrews, J E; Appleby, R B; Archilli, F; d'Argent, P; Arnau Romeu, J; Artamonov, A; Artuso, M; Aslanides, E; Atzeni, M; Auriemma, G; Baalouch, M; Babuschkin, I; Bachmann, S; Back, J J; Badalov, A; Baesso, C; Baker, S; Balagura, V; Baldini, W; Baranov, A; Barlow, R J; Barschel, C; Barsuk, S; Barter, W; Baryshnikov, F; Batozskaya, V; Battista, V; Bay, A; Beaucourt, L; Beddow, J; Bedeschi, F; Bediaga, I; Beiter, A; Bel, L J; Beliy, N; Bellee, V; Belloli, N; Belous, K; Belyaev, I; Ben-Haim, E; Bencivenni, G; Benson, S; Beranek, S; Berezhnoy, A; Bernet, R; Berninghoff, D; Bertholet, E; Bertolin, A; Betancourt, C; Betti, F; Bettler, M-O; van Beuzekom, M; Bezshyiko, Ia; Bifani, S; Billoir, P; Birnkraut, A; Bizzeti, A; Bjørn, M; Blake, T; Blanc, F; 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Yu, J; Yuan, X; Yushchenko, O; Zarebski, K A; Zavertyaev, M; Zhang, L; Zhang, Y; Zhelezov, A; Zheng, Y; Zhu, X; Zhukov, V; Zonneveld, J B; Zucchelli, S

    2018-03-23

    A measurement is reported of the ratio of branching fractions R(J/ψ)=B(B_{c}^{+}→J/ψτ^{+}ν_{τ})/B(B_{c}^{+}→J/ψμ^{+}ν_{μ}), where the τ^{+} lepton is identified in the decay mode τ^{+}→μ^{+}ν_{μ}ν[over ¯]_{τ}. This analysis uses a sample of proton-proton collision data corresponding to 3.0  fb^{-1} of integrated luminosity recorded with the LHCb experiment at center-of-mass energies of 7 and 8 TeV. A signal is found for the decay B_{c}^{+}→J/ψτ^{+}ν_{τ} at a significance of 3 standard deviations corrected for systematic uncertainty, and the ratio of the branching fractions is measured to be R(J/ψ)=0.71±0.17(stat)±0.18(syst). This result lies within 2 standard deviations above the range of central values currently predicted by the standard model.

  11. Measurement of prompt J/ ψ pair production in pp collisions at = 7 Tev

    NASA Astrophysics Data System (ADS)

    Khachatryan, V.; Sirunyan, A. M.; Tumasyan, A.; Adam, W.; Bergauer, T.; Dragicevic, M.; Erö, J.; Fabjan, C.; Friedl, M.; Frühwirth, R.; Ghete, V. M.; Hartl, C.; Hörmann, N.; Hrubec, J.; Jeitler, M.; Kiesenhofer, W.; Knünz, V.; Krammer, M.; Krätschmer, I.; Liko, D.; Mikulec, I.; Rabady, D.; Rahbaran, B.; Rohringer, H.; Schöfbeck, R.; Strauss, J.; Taurok, A.; Treberer-Treberspurg, W.; Waltenberger, W.; Wulz, C.-E.; Mossolov, V.; Shumeiko, N.; Gonzalez, J. Suarez; Alderweireldt, S.; Bansal, M.; Bansal, S.; Cornelis, T.; De Wolf, E. A.; Janssen, X.; Knutsson, A.; Luyckx, S.; Ochesanu, S.; Roland, B.; Rougny, R.; Van De Klundert, M.; Van Haevermaet, H.; Van Mechelen, P.; Van Remortel, N.; Van Spilbeeck, A.; Blekman, F.; Blyweert, S.; D'Hondt, J.; Daci, N.; Heracleous, N.; Keaveney, J.; Kim, T. J.; Lowette, S.; Maes, M.; Olbrechts, A.; Python, Q.; Strom, D.; Tavernier, S.; Van Doninck, W.; Van Mulders, P.; Van Onsem, G. 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E.; Carvalho, W.; Chinellato, J.; Custódio, A.; Da Costa, E. M.; De Jesus Damiao, D.; De Oliveira Martins, C.; De Souza, S. Fonseca; Malbouisson, H.; Figueiredo, D. Matos; Mundim, L.; Nogima, H.; Da Silva, W. L. Prado; Santaolalla, J.; Santoro, A.; Sznajder, A.; Manganote, E. J. Tonelli; Pereira, A. Vilela; Bernardes, C. A.; Dias, F. A.; Tomei, T. R. Fernandez Perez; Gregores, E. M.; Mercadante, P. G.; Novaes, S. F.; Padula, Sandra S.; Aleksandrov, A.; Genchev, V.; Iaydjiev, P.; Marinov, A.; Piperov, S.; Rodozov, M.; Sultanov, G.; Vutova, M.; Dimitrov, A.; Glushkov, I.; Hadjiiska, R.; Kozhuharov, V.; Litov, L.; Pavlov, B.; Petkov, P.; Bian, J. G.; Chen, G. M.; Chen, H. S.; Chen, M.; Du, R.; Jiang, C. H.; Liang, D.; Liang, S.; Plestina, R.; Tao, J.; Wang, X.; Wang, Z.; Asawatangtrakuldee, C.; Ban, Y.; Guo, Y.; Li, W.; Liu, S.; Mao, Y.; Qian, S. J.; Teng, H.; Wang, D.; Zhang, L.; Zou, W.; Avila, C.; Sierra, L. F. Chaparro; Florez, C.; Gomez, J. P.; Moreno, B. Gomez; Sanabria, J. 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S.; Kirschenmann, H.; Klanner, R.; Kogler, R.; Lange, J.; Lapsien, T.; Lenz, T.; Marchesini, I.; Ott, J.; Peiffer, T.; Pietsch, N.; Rathjens, D.; Sander, C.; Schettler, H.; Schleper, P.; Schlieckau, E.; Schmidt, A.; Seidel, M.; Sibille, J.; Sola, V.; Stadie, H.; Steinbrück, G.; Troendle, D.; Usai, E.; Vanelderen, L.; Barth, C.; Baus, C.; Berger, J.; Böser, C.; Butz, E.; Chwalek, T.; De Boer, W.; Descroix, A.; Dierlamm, A.; Feindt, M.; Frensch, F.; Giffels, M.; Hartmann, F.; Hauth, T.; Husemann, U.; Katkov, I.; Kornmayer, A.; Kuznetsova, E.; Pardo, P. Lobelle; Mozer, M. U.; Müller, Th.; Nürnberg, A.; Quast, G.; Rabbertz, K.; Ratnikov, F.; Röcker, S.; Simonis, H. J.; Stober, F. M.; Ulrich, R.; Wagner-Kuhr, J.; Wayand, S.; Weiler, T.; Wolf, R.; Anagnostou, G.; Daskalakis, G.; Geralis, T.; Giakoumopoulou, V. A.; Kyriakis, A.; Loukas, D.; Markou, A.; Markou, C.; Psallidas, A.; Topsis-Giotis, I.; Panagiotou, A.; Saoulidou, N.; Stiliaris, E.; Aslanoglou, X.; Evangelou, I.; Flouris, G.; Foudas, C.; Kokkas, P.; Manthos, N.; Papadopoulos, I.; Paradas, E.; Bencze, G.; Hajdu, C.; Hidas, P.; Horvath, D.; Sikler, F.; Veszpremi, V.; Vesztergombi, G.; Zsigmond, A. J.; Beni, N.; Czellar, S.; Karancsi, J.; Molnar, J.; Palinkas, J.; Szillasi, Z.; Raics, P.; Trocsanyi, Z. L.; Ujvari, B.; Swain, S. K.; Beri, S. B.; Bhatnagar, V.; Dhingra, N.; Gupta, R.; Bhawandeep, U.; Kalsi, A. K.; Kaur, M.; Mittal, M.; Nishu, N.; Singh, J. B.; Kumar, Ashok; Kumar, Arun; Ahuja, S.; Bhardwaj, A.; Choudhary, B. C.; Kumar, A.; Malhotra, S.; Naimuddin, M.; Ranjan, K.; Sharma, V.; Banerjee, S.; Bhattacharya, S.; Chatterjee, K.; Dutta, S.; Gomber, B.; Jain, Sa.; Jain, Sh.; Khurana, R.; Modak, A.; Mukherjee, S.; Roy, D.; Sarkar, S.; Sharan, M.; Abdulsalam, A.; Dutta, D.; Kailas, S.; Kumar, V.; Mohanty, A. K.; Pant, L. M.; Shukla, P.; Topkar, A.; Aziz, T.; Banerjee, S.; Chatterjee, R. M.; Dewanjee, R. K.; Dugad, S.; Ganguly, S.; Ghosh, S.; Guchait, M.; Gurtu, A.; Kole, G.; Kumar, S.; Maity, M.; Majumder, G.; Mazumdar, K.; Mohanty, G. B.; Parida, B.; Sudhakar, K.; Wickramage, N.; Bakhshiansohi, H.; Behnamian, H.; Etesami, S. M.; Fahim, A.; Goldouzian, R.; Jafari, A.; Khakzad, M.; Najafabadi, M. Mohammadi; Naseri, M.; Mehdiabadi, S. Paktinat; Safarzadeh, B.; Zeinali, M.; Felcini, M.; Grunewald, M.; Abbrescia, M.; Barbone, L.; Calabria, C.; Chhibra, S. S.; Colaleo, A.; Creanza, D.; De Filippis, N.; De Palma, M.; Fiore, L.; Iaselli, G.; Maggi, G.; Maggi, M.; My, S.; Nuzzo, S.; Pompili, A.; Pugliese, G.; Radogna, R.; Selvaggi, G.; Silvestris, L.; Singh, G.; Venditti, R.; Verwilligen, P.; Zito, G.; Abbiendi, G.; Benvenuti, A. C.; Bonacorsi, D.; Braibant-Giacomelli, S.; Brigliadori, L.; Campanini, R.; Capiluppi, P.; Castro, A.; Cavallo, F. R.; Codispoti, G.; Cuffiani, M.; Dallavalle, G. M.; Fabbri, F.; Fanfani, A.; Fasanella, D.; Giacomelli, P.; Grandi, C.; Guiducci, L.; Marcellini, S.; Masetti, G.; Montanari, A.; Navarria, F. L.; Perrotta, A.; Primavera, F.; Rossi, A. M.; Rovelli, T.; Siroli, G. P.; Tosi, N.; Travaglini, R.; Albergo, S.; Cappello, G.; Chiorboli, M.; Costa, S.; Giordano, F.; Potenza, R.; Tricomi, A.; Tuve, C.; Barbagli, G.; Ciulli, V.; Civinini, C.; D'Alessandro, R.; Focardi, E.; Gallo, E.; Gonzi, S.; Gori, V.; Lenzi, P.; Meschini, M.; Paoletti, S.; Sguazzoni, G.; Tropiano, A.; Benussi, L.; Bianco, S.; Fabbri, F.; Piccolo, D.; Ferro, F.; Vetere, M. Lo; Robutti, E.; Tosi, S.; Dinardo, M. E.; Fiorendi, S.; Gennai, S.; Gerosa, R.; Ghezzi, A.; Govoni, P.; Lucchini, M. T.; Malvezzi, S.; Manzoni, R. A.; Martelli, A.; Marzocchi, B.; Menasce, D.; Moroni, L.; Paganoni, M.; Pedrini, D.; Ragazzi, S.; Redaelli, N.; de Fatis, T. Tabarelli; Buontempo, S.; Cavallo, N.; Di Guida, S.; Fabozzi, F.; Iorio, A. O. M.; Lista, L.; Meola, S.; Merola, M.; Paolucci, P.; Bellato, M.; Bisello, D.; Branca, A.; Carlin, R.; Checchia, P.; Dall'Osso, M.; Dorigo, T.; Dosselli, U.; Galanti, M.; Gasparini, F.; Gasparini, U.; Giubilato, P.; Gonella, F.; Gozzelino, A.; Kanishchev, K.; Lacaprara, S.; Margoni, M.; Meneguzzo, A. T.; Montecassiano, F.; Pazzini, J.; Pozzobon, N.; Ronchese, P.; Simonetto, F.; Torassa, E.; Tosi, M.; Zotto, P.; Zucchetta, A.; Gabusi, M.; Ratti, S. P.; Riccardi, C.; Salvini, P.; Vitulo, P.; Biasini, M.; Bilei, G. M.; Ciangottini, D.; Fanò, L.; Lariccia, P.; Mantovani, G.; Menichelli, M.; Romeo, F.; Saha, A.; Santocchia, A.; Spiezia, A.; Androsov, K.; Azzurri, P.; Bagliesi, G.; Bernardini, J.; Boccali, T.; Broccolo, G.; Castaldi, R.; Ciocci, M. A.; Dell'Orso, R.; Donato, S.; Fiori, F.; Foà, L.; Giassi, A.; Grippo, M. T.; Ligabue, F.; Lomtadze, T.; Martini, L.; Messineo, A.; Moon, C. S.; Palla, F.; Rizzi, A.; Savoy-Navarro, A.; Serban, A. T.; Spagnolo, P.; Squillacioti, P.; Tenchini, R.; Tonelli, G.; Venturi, A.; Verdini, P. G.; Vernieri, C.; Barone, L.; Cavallari, F.; Del Re, D.; Diemoz, M.; Grassi, M.; Jorda, C.; Longo, E.; Margaroli, F.; Meridiani, P.; Micheli, F.; Nourbakhsh, S.; Organtini, G.; Paramatti, R.; Rahatlou, S.; Rovelli, C.; Santanastasio, F.; Soffi, L.; Traczyk, P.; Amapane, N.; Arcidiacono, R.; Argiro, S.; Arneodo, M.; Bellan, R.; Biino, C.; Cartiglia, N.; Casasso, S.; Costa, M.; Degano, A.; Demaria, N.; Finco, L.; Mariotti, C.; Maselli, S.; Migliore, E.; Monaco, V.; Musich, M.; Obertino, M. M.; Ortona, G.; Pacher, L.; Pastrone, N.; Pelliccioni, M.; Angioni, G. L. Pinna; Potenza, A.; Romero, A.; Ruspa, M.; Sacchi, R.; Solano, A.; Staiano, A.; Tamponi, U.; Belforte, S.; Candelise, V.; Casarsa, M.; Cossutti, F.; Ricca, G. Della; Gobbo, B.; La Licata, C.; Marone, M.; Montanino, D.; Schizzi, A.; Umer, T.; Zanetti, A.; Chang, S.; Kropivnitskaya, A.; Nam, S. K.; Kim, D. H.; Kim, G. N.; Kim, M. S.; Kong, D. J.; Lee, S.; Oh, Y. D.; Park, H.; Sakharov, A.; Son, D. C.; Kim, J. Y.; Song, S.; Choi, S.; Gyun, D.; Hong, B.; Jo, M.; Kim, H.; Kim, Y.; Lee, B.; Lee, K. S.; Park, S. K.; Roh, Y.; Choi, M.; Kim, J. H.; Park, I. C.; Park, S.; Ryu, G.; Ryu, M. S.; Choi, Y.; Choi, Y. K.; Goh, J.; Kwon, E.; Lee, J.; Seo, H.; Yu, I.; Juodagalvis, A.; Komaragiri, J. R.; Castilla-Valdez, H.; De La Cruz-Burelo, E.; La Cruz, I. Heredia-de; Lopez-Fernandez, R.; Sanchez-Hernandez, A.; Moreno, S. Carrillo; Valencia, F. Vazquez; Pedraza, I.; Ibarguen, H. A. Salazar; Linares, E. Casimiro; Pineda, A. Morelos; Krofcheck, D.; Butler, P. H.; Reucroft, S.; Ahmad, A.; Ahmad, M.; Hassan, Q.; Hoorani, H. R.; Khalid, S.; Khan, W. A.; Khurshid, T.; Shah, M. A.; Shoaib, M.; Bialkowska, H.; Bluj, M.; Boimska, B.; Frueboes, T.; Górski, M.; Kazana, M.; Nawrocki, K.; Romanowska-Rybinska, K.; Szleper, M.; Zalewski, P.; Brona, G.; Bunkowski, K.; Cwiok, M.; Dominik, W.; Doroba, K.; Kalinowski, A.; Konecki, M.; Krolikowski, J.; Misiura, M.; Olszewski, M.; Wolszczak, W.; Bargassa, P.; Da Cruz E Silva, C. Beirão; Faccioli, P.; Parracho, P. G. Ferreira; Gallinaro, M.; Nguyen, F.; Antunes, J. Rodrigues; Seixas, J.; Varela, J.; Vischia, P.; Afanasiev, S.; Golutvin, I.; Karjavin, V.; Konoplyanikov, V.; Korenkov, V.; Lanev, A.; Malakhov, A.; Matveev, V.; Mitsyn, V. V.; Moisenz, P.; Palichik, V.; Perelygin, V.; Shmatov, S.; Skatchkov, N.; Smirnov, V.; Tikhonenko, E.; Yuldashev, B. S.; Zarubin, A.; Golovtsov, V.; Ivanov, Y.; Kim, V.; Levchenko, P.; Murzin, V.; Oreshkin, V.; Smirnov, I.; Sulimov, V.; Uvarov, L.; Vavilov, S.; Vorobyev, A.; Vorobyev, An.; Andreev, Yu.; Dermenev, A.; Gninenko, S.; Golubev, N.; Kirsanov, M.; Krasnikov, N.; Pashenkov, A.; Tlisov, D.; Toropin, A.; Epshteyn, V.; Gavrilov, V.; Lychkovskaya, N.; Popov, V.; Safronov, G.; Semenov, S.; Spiridonov, A.; Stolin, V.; Vlasov, E.; Zhokin, A.; Andreev, V.; Azarkin, M.; Dremin, I.; Kirakosyan, M.; Leonidov, A.; Mesyats, G.; Rusakov, S. V.; Vinogradov, A.; Belyaev, A.; Boos, E.; Dubinin, M.; Dudko, L.; Ershov, A.; Gribushin, A.; Klyukhin, V.; Kodolova, O.; Lokhtin, I.; Obraztsov, S.; Petrushanko, S.; Savrin, V.; Snigirev, A.; Azhgirey, I.; Bayshev, I.; Bitioukov, S.; Kachanov, V.; Kalinin, A.; Konstantinov, D.; Krychkine, V.; Petrov, V.; Ryutin, R.; Sobol, A.; Tourtchanovitch, L.; Troshin, S.; Tyurin, N.; Uzunian, A.; Volkov, A.; Adzic, P.; Dordevic, M.; Ekmedzic, M.; Milosevic, J.; Maestre, J. Alcaraz; Battilana, C.; Calvo, E.; Cerrada, M.; Llatas, M. Chamizo; Colino, N.; De La Cruz, B.; Peris, A. Delgado; Vázquez, D. Domínguez; Del Valle, A. Escalante; Bedoya, C. Fernandez; Ramos, J. P. Fernández; Flix, J.; Fouz, M. C.; Garcia-Abia, P.; Lopez, O. Gonzalez; Lopez, S. Goy; Hernandez, J. M.; Josa, M. I.; Merino, G.; De Martino, E. Navarro; Yzquierdo, A. Pérez-Calero; Pelayo, J. Puerta; Olmeda, A. Quintario; Redondo, I.; Romero, L.; Soares, M. S.; Albajar, C.; de Trocóniz, J. F.; Missiroli, M.; Brun, H.; Cuevas, J.; Menendez, J. Fernandez; Folgueras, S.; Caballero, I. Gonzalez; Iglesias, L. Lloret; Cifuentes, J. A. Brochero; Cabrillo, I. J.; Calderon, A.; Campderros, J. Duarte; Fernandez, M.; Gomez, G.; Graziano, A.; Virto, A. Lopez; Marco, J.; Marco, R.; Rivero, C. Martinez; Matorras, F.; Sanchez, F. J. Munoz; Gomez, J. Piedra; Rodrigo, T.; Rodríguez-Marrero, A. Y.; Ruiz-Jimeno, A.; Scodellaro, L.; Vila, I.; Cortabitarte, R. Vilar; Abbaneo, D.; Auffray, E.; Auzinger, G.; Bachtis, M.; Baillon, P.; Ball, A. H.; Barney, D.; Benaglia, A.; Bendavid, J.; Benhabib, L.; Benitez, J. F.; Bernet, C.; Bianchi, G.; Bloch, P.; Bocci, A.; Bonato, A.; Bondu, O.; Botta, C.; Breuker, H.; Camporesi, T.; Cerminara, G.; Colafranceschi, S.; D'Alfonso, M.; d'Enterria, D.; Dabrowski, A.; David, A.; De Guio, F.; De Roeck, A.; De Visscher, S.; Dobson, M.; Dupont-Sagorin, N.; Elliott-Peisert, A.; Eugster, J.; Franzoni, G.; Funk, W.; Gigi, D.; Gill, K.; Giordano, D.; Girone, M.; Glege, F.; Guida, R.; Gundacker, S.; Guthoff, M.; Hammer, J.; Hansen, M.; Harris, P.; Hegeman, J.; Innocente, V.; Janot, P.; Kousouris, K.; Krajczar, K.; Lecoq, P.; Lourenço, C.; Magini, N.; Malgeri, L.; Mannelli, M.; Marrouche, J.; Masetti, L.; Meijers, F.; Mersi, S.; Meschi, E.; Moortgat, F.; Morovic, S.; Mulders, M.; Musella, P.; Orsini, L.; Pape, L.; Perez, E.; Perrozzi, L.; Petrilli, A.; Petrucciani, G.; Pfeiffer, A.; Pierini, M.; Pimiä, M.; Piparo, D.; Plagge, M.; Racz, A.; Rolandi, G.; Rovere, M.; Sakulin, H.; Schäfer, C.; Schwick, C.; Sekmen, S.; Sharma, A.; Siegrist, P.; Silva, P.; Simon, M.; Sphicas, P.; Spiga, D.; Steggemann, J.; Stieger, B.; Stoye, M.; Treille, D.; Tsirou, A.; Veres, G. I.; Vlimant, J. R.; Wardle, N.; Wöhri, H. K.; Zeuner, W. D.; Bertl, W.; Deiters, K.; Erdmann, W.; Horisberger, R.; Ingram, Q.; Kaestli, H. C.; König, S.; Kotlinski, D.; Langenegger, U.; Renker, D.; Rohe, T.; Bachmair, F.; Bäni, L.; Bianchini, L.; Bortignon, P.; Buchmann, M. A.; Casal, B.; Chanon, N.; Deisher, A.; Dissertori, G.; Dittmar, M.; Donegà, M.; Dünser, M.; Eller, P.; Grab, C.; Hits, D.; Lustermann, W.; Mangano, B.; Marini, A. C.; del Arbol, P. Martinez Ruiz; Meister, D.; Mohr, N.; Nägeli, C.; Nessi-Tedaldi, F.; Pandolfi, F.; Pauss, F.; Peruzzi, M.; Quittnat, M.; Rebane, L.; Rossini, M.; Starodumov, A.; Takahashi, M.; Theofilatos, K.; Wallny, R.; Weber, H. A.; Amsler, C.; Canelli, M. F.; Chiochia, V.; De Cosa, A.; Hinzmann, A.; Hreus, T.; Kilminster, B.; Mejias, B. Millan; Ngadiuba, J.; Robmann, P.; Ronga, F. J.; Snoek, H.; Taroni, S.; Verzetti, M.; Yang, Y.; Cardaci, M.; Chen, K. H.; Ferro, C.; Kuo, C. M.; Lin, W.; Lu, Y. J.; Volpe, R.; Yu, S. S.; Chang, P.; Chang, Y. H.; Chang, Y. W.; Chao, Y.; Chen, K. F.; Chen, P. H.; Dietz, C.; Grundler, U.; Hou, W.-S.; Kao, K. Y.; Lei, Y. J.; Liu, Y. F.; Lu, R.-S.; Majumder, D.; Petrakou, E.; Tzeng, Y. M.; Wilken, R.; Asavapibhop, B.; Srimanobhas, N.; Suwonjandee, N.; Adiguzel, A.; Bakirci, M. N.; Cerci, S.; Dozen, C.; Dumanoglu, I.; Eskut, E.; Girgis, S.; Gokbulut, G.; Gurpinar, E.; Hos, I.; Kangal, E. E.; Topaksu, A. Kayis; Onengut, G.; Ozdemir, K.; Ozturk, S.; Polatoz, A.; Sogut, K.; Cerci, D. Sunar; Tali, B.; Topakli, H.; Vergili, M.; Akin, I. V.; Bilin, B.; Bilmis, S.; Gamsizkan, H.; Karapinar, G.; Ocalan, K.; Surat, U. E.; Yalvac, M.; Zeyrek, M.; Gülmez, E.; Isildak, B.; Kaya, M.; Kaya, O.; Bahtiyar, H.; Barlas, E.; Cankocak, K.; Vardarlı, F. I.; Yücel, M.; Levchuk, L.; Sorokin, P.; Brooke, J. J.; Clement, E.; Cussans, D.; Flacher, H.; Frazier, R.; Goldstein, J.; Grimes, M.; Heath, G. P.; Heath, H. F.; Jacob, J.; Kreczko, L.; Lucas, C.; Meng, Z.; Newbold, D. M.; Paramesvaran, S.; Poll, A.; Senkin, S.; Smith, V. J.; Williams, T.; Bell, K. W.; Belyaev, A.; Brew, C.; Brown, R. M.; Cockerill, D. J. A.; Coughlan, J. A.; Harder, K.; Harper, S.; Olaiya, E.; Petyt, D.; Shepherd-Themistocleous, C. H.; Thea, A.; Tomalin, I. R.; Womersley, W. J.; Worm, S. D.; Baber, M.; Bainbridge, R.; Buchmuller, O.; Burton, D.; Colling, D.; Cripps, N.; Cutajar, M.; Dauncey, P.; Davies, G.; Negra, M. Della; Dunne, P.; Ferguson, W.; Fulcher, J.; Futyan, D.; Gilbert, A.; Hall, G.; Iles, G.; Jarvis, M.; Karapostoli, G.; Kenzie, M.; Lane, R.; Lucas, R.; Lyons, L.; Magnan, A.-M.; Malik, S.; Mathias, B.; Nash, J.; Nikitenko, A.; Pela, J.; Pesaresi, M.; Petridis, K.; Raymond, D. M.; Rogerson, S.; Rose, A.; Seez, C.; Sharp, P.; Tapper, A.; Acosta, M. Vazquez; Virdee, T.; Cole, J. E.; Hobson, P. R.; Khan, A.; Kyberd, P.; Leggat, D.; Leslie, D.; Martin, W.; Reid, I. D.; Symonds, P.; Teodorescu, L.; Turner, M.; Dittmann, J.; Hatakeyama, K.; Kasmi, A.; Liu, H.; Scarborough, T.; Charaf, O.; Cooper, S. I.; Henderson, C.; Rumerio, P.; Avetisyan, A.; Bose, T.; Fantasia, C.; Heister, A.; Lawson, P.; Richardson, C.; Rohlf, J.; Sperka, D.; John, J. St.; Sulak, L.; Alimena, J.; Berry, E.; Bhattacharya, S.; Christopher, G.; Cutts, D.; Demiragli, Z.; Ferapontov, A.; Garabedian, A.; Heintz, U.; Jabeen, S.; Kukartsev, G.; Laird, E.; Landsberg, G.; Luk, M.; Narain, M.; Segala, M.; Sinthuprasith, T.; Speer, T.; Swanson, J.; Breedon, R.; Breto, G.; De La Barca Sanchez, M. Calderon; Chauhan, S.; Chertok, M.; Conway, J.; Conway, R.; Cox, P. T.; Erbacher, R.; Gardner, M.; Ko, W.; Lander, R.; Miceli, T.; Mulhearn, M.; Pellett, D.; Pilot, J.; Ricci-Tam, F.; Searle, M.; Shalhout, S.; Smith, J.; Squires, M.; Stolp, D.; Tripathi, M.; Wilbur, S.; Yohay, R.; Cousins, R.; Everaerts, P.; Farrell, C.; Hauser, J.; Ignatenko, M.; Rakness, G.; Takasugi, E.; Valuev, V.; Weber, M.; Babb, J.; Burt, K.; Clare, R.; Ellison, J.; Gary, J. W.; Hanson, G.; Heilman, J.; Rikova, M. Ivova; Jandir, P.; Kennedy, E.; Lacroix, F.; Liu, H.; Long, O. R.; Luthra, A.; Malberti, M.; Nguyen, H.; Shrinivas, A.; Sumowidagdo, S.; Wimpenny, S.; Andrews, W.; Branson, J. G.; Cerati, G. B.; Cittolin, S.; D'Agnolo, R. T.; Evans, D.; Holzner, A.; Kelley, R.; Klein, D.; Lebourgeois, M.; Letts, J.; Macneill, I.; Olivito, D.; Padhi, S.; Palmer, C.; Pieri, M.; Sani, M.; Sharma, V.; Simon, S.; Sudano, E.; Tadel, M.; Tu, Y.; Vartak, A.; Welke, C.; Würthwein, F.; Yagil, A.; Yoo, J.; Barge, D.; Bradmiller-Feld, J.; Campagnari, C.; Danielson, T.; Dishaw, A.; Flowers, K.; Sevilla, M. Franco; Geffert, P.; George, C.; Golf, F.; Gouskos, L.; Incandela, J.; Justus, C.; Mccoll, N.; Richman, J.; Stuart, D.; To, W.; West, C.; Apresyan, A.; Bornheim, A.; Bunn, J.; Chen, Y.; Di Marco, E.; Duarte, J.; Mott, A.; Newman, H. B.; Pena, C.; Rogan, C.; Spiropulu, M.; Timciuc, V.; Wilkinson, R.; Xie, S.; Zhu, R. Y.; Azzolini, V.; Calamba, A.; Ferguson, T.; Iiyama, Y.; Paulini, M.; Russ, J.; Vogel, H.; Vorobiev, I.; Cumalat, J. P.; Drell, B. R.; Ford, W. T.; Gaz, A.; Lopez, E. Luiggi; Nauenberg, U.; Smith, J. G.; Stenson, K.; Ulmer, K. A.; Wagner, S. R.; Alexander, J.; Chatterjee, A.; Chu, J.; Dittmer, S.; Eggert, N.; Mirman, N.; Kaufman, G. Nicolas; Patterson, J. R.; Ryd, A.; Salvati, E.; Skinnari, L.; Sun, W.; Teo, W. D.; Thom, J.; Thompson, J.; Tucker, J.; Weng, Y.; Winstrom, L.; Wittich, P.; Winn, D.; Abdullin, S.; Albrow, M.; Anderson, J.; Apollinari, G.; Bauerdick, L. A. T.; Beretvas, A.; Berryhill, J.; Bhat, P. C.; Burkett, K.; Butler, J. N.; Cheung, H. W. K.; Chlebana, F.; Cihangir, S.; Elvira, V. D.; Fisk, I.; Freeman, J.; Gottschalk, E.; Gray, L.; Green, D.; Grünendahl, S.; Gutsche, O.; Hanlon, J.; Hare, D.; Harris, R. M.; Hirschauer, J.; Hooberman, B.; Jindariani, S.; Johnson, M.; Joshi, U.; Kaadze, K.; Klima, B.; Kreis, B.; Kwan, S.; Linacre, J.; Lincoln, D.; Lipton, R.; Liu, T.; Lykken, J.; Maeshima, K.; Marraffino, J. M.; Outschoorn, V. I. Martinez; Maruyama, S.; Mason, D.; McBride, P.; Mishra, K.; Mrenna, S.; Musienko, Y.; Nahn, S.; Newman-Holmes, C.; O'Dell, V.; Prokofyev, O.; Sexton-Kennedy, E.; Sharma, S.; Soha, A.; Spalding, W. J.; Spiegel, L.; Taylor, L.; Tkaczyk, S.; Tran, N. V.; Uplegger, L.; Vaandering, E. W.; Vidal, R.; Whitbeck, A.; Whitmore, J.; Yang, F.; Acosta, D.; Avery, P.; Bourilkov, D.; Carver, M.; Cheng, T.; Curry, D.; Das, S.; De Gruttola, M.; Di Giovanni, G. P.; Field, R. D.; Fisher, M.; Furic, I. K.; Hugon, J.; Konigsberg, J.; Korytov, A.; Kypreos, T.; Low, J. F.; Matchev, K.; Milenovic, P.; Mitselmakher, G.; Muniz, L.; Rinkevicius, A.; Shchutska, L.; Skhirtladze, N.; Snowball, M.; Yelton, J.; Zakaria, M.; Hewamanage, S.; Linn, S.; Markowitz, P.; Martinez, G.; Rodriguez, J. L.; Adams, T.; Askew, A.; Bochenek, J.; Diamond, B.; Haas, J.; Hagopian, S.; Hagopian, V.; Johnson, K. F.; Prosper, H.; Veeraraghavan, V.; Weinberg, M.; Baarmand, M. M.; Hohlmann, M.; Kalakhety, H.; Yumiceva, F.; Adams, M. R.; Apanasevich, L.; Bazterra, V. E.; Berry, D.; Betts, R. R.; Bucinskaite, I.; Cavanaugh, R.; Evdokimov, O.; Gauthier, L.; Gerber, C. E.; Hofman, D. J.; Khalatyan, S.; Kurt, P.; Moon, D. H.; O'Brien, C.; Silkworth, C.; Turner, P.; Varelas, N.; Albayrak, E. A.; Bilki, B.; Clarida, W.; Dilsiz, K.; Duru, F.; Haytmyradov, M.; Merlo, J.-P.; Mermerkaya, H.; Mestvirishvili, A.; Moeller, A.; Nachtman, J.; Ogul, H.; Onel, Y.; Ozok, F.; Penzo, A.; Rahmat, R.; Sen, S.; Tan, P.; Tiras, E.; Wetzel, J.; Yetkin, T.; Yi, K.; Barnett, B. A.; Blumenfeld, B.; Bolognesi, S.; Fehling, D.; Gritsan, A. V.; Maksimovic, P.; Martin, C.; Swartz, M.; Baringer, P.; Bean, A.; Benelli, G.; Bruner, C.; Gray, J.; Kenny, R. P.; Malek, M.; Murray, M.; Noonan, D.; Sanders, S.; Sekaric, J.; Stringer, R.; Wang, Q.; Wood, J. S.; Barfuss, A. F.; Chakaberia, I.; Ivanov, A.; Khalil, S.; Makouski, M.; Maravin, Y.; Saini, L. K.; Shrestha, S.; Svintradze, I.; Gronberg, J.; Lange, D.; Rebassoo, F.; Wright, D.; Baden, A.; Calvert, B.; Eno, S. C.; Gomez, J. A.; Hadley, N. J.; Kellogg, R. G.; Kolberg, T.; Lu, Y.; Marionneau, M.; Mignerey, A. C.; Pedro, K.; Skuja, A.; Tonjes, M. B.; Tonwar, S. C.; Apyan, A.; Barbieri, R.; Bauer, G.; Busza, W.; Cali, I. A.; Chan, M.; Di Matteo, L.; Dutta, V.; Ceballos, G. Gomez; Goncharov, M.; Gulhan, D.; Klute, M.; Lai, Y. S.; Lee, Y.-J.; Levin, A.; Luckey, P. D.; Ma, T.; Paus, C.; Ralph, D.; Roland, C.; Roland, G.; Stephans, G. S. F.; Stöckli, F.; Sumorok, K.; Velicanu, D.; Veverka, J.; Wyslouch, B.; Yang, M.; Zanetti, M.; Zhukova, V.; Dahmes, B.; Gude, A.; Kao, S. C.; Klapoetke, K.; Kubota, Y.; Mans, J.; Pastika, N.; Rusack, R.; Singovsky, A.; Tambe, N.; Turkewitz, J.; Acosta, J. G.; Oliveros, S.; Avdeeva, E.; Bloom, K.; Bose, S.; Claes, D. R.; Dominguez, A.; Suarez, R. Gonzalez; Keller, J.; Knowlton, D.; Kravchenko, I.; Lazo-Flores, J.; Malik, S.; Meier, F.; Snow, G. R.; Dolen, J.; Godshalk, A.; Iashvili, I.; Kharchilava, A.; Kumar, A.; Rappoccio, S.; Alverson, G.; Barberis, E.; Baumgartel, D.; Chasco, M.; Haley, J.; Massironi, A.; Morse, D. M.; Nash, D.; Orimoto, T.; Trocino, D.; Wang, R. J.; Wood, D.; Zhang, J.; Hahn, K. A.; Kubik, A.; Mucia, N.; Odell, N.; Pollack, B.; Pozdnyakov, A.; Schmitt, M.; Stoynev, S.; Sung, K.; Velasco, M.; Won, S.; Brinkerhoff, A.; Chan, K. M.; Drozdetskiy, A.; Hildreth, M.; Jessop, C.; Karmgard, D. J.; Kellams, N.; Lannon, K.; Luo, W.; Lynch, S.; Marinelli, N.; Pearson, T.; Planer, M.; Ruchti, R.; Valls, N.; Wayne, M.; Wolf, M.; Woodard, A.; Antonelli, L.; Brinson, J.; Bylsma, B.; Durkin, L. S.; Flowers, S.; Hill, C.; Hughes, R.; Kotov, K.; Ling, T. Y.; Puigh, D.; Rodenburg, M.; Smith, G.; Vuosalo, C.; Winer, B. L.; Wolfe, H.; Wulsin, H. W.; Driga, O.; Elmer, P.; Hebda, P.; Hunt, A.; Koay, S. A.; Lujan, P.; Marlow, D.; Medvedeva, T.; Mooney, M.; Olsen, J.; Piroué, P.; Quan, X.; Saka, H.; Stickland, D.; Tully, C.; Werner, J. S.; Zenz, S. C.; Zuranski, A.; Brownson, E.; Mendez, H.; Vargas, J. E. Ramirez; Alagoz, E.; Barnes, V. E.; Benedetti, D.; Bolla, G.; Bortoletto, D.; De Mattia, M.; Hu, Z.; Jha, M. K.; Jones, M.; Jung, K.; Kress, M.; Leonardo, N.; Pegna, D. Lopes; Maroussov, V.; Merkel, P.; Miller, D. H.; Neumeister, N.; Radburn-Smith, B. C.; Shi, X.; Shipsey, I.; Silvers, D.; Svyatkovskiy, A.; Wang, F.; Xie, W.; Xu, L.; Yoo, H. D.; Zablocki, J.; Zheng, Y.; Parashar, N.; Stupak, J.; Adair, A.; Akgun, B.; Ecklund, K. M.; Geurts, F. J. M.; Li, W.; Michlin, B.; Padley, B. P.; Redjimi, R.; Roberts, J.; Zabel, J.; Betchart, B.; Bodek, A.; Covarelli, R.; de Barbaro, P.; Demina, R.; Eshaq, Y.; Ferbel, T.; Garcia-Bellido, A.; Goldenzweig, P.; Han, J.; Harel, A.; Khukhunaishvili, A.; Miner, D. C.; Petrillo, G.; Vishnevskiy, D.; Ciesielski, R.; Demortier, L.; Goulianos, K.; Lungu, G.; Mesropian, C.; Arora, S.; Barker, A.; Chou, J. P.; Contreras-Campana, C.; Contreras-Campana, E.; Duggan, D.; Ferencek, D.; Gershtein, Y.; Gray, R.; Halkiadakis, E.; Hidas, D.; Lath, A.; Panwalkar, S.; Park, M.; Patel, R.; Rekovic, V.; Salur, S.; Schnetzer, S.; Seitz, C.; Somalwar, S.; Stone, R.; Thomas, S.; Thomassen, P.; Walker, M.; Rose, K.; Spanier, S.; York, A.; Bouhali, O.; Eusebi, R.; Flanagan, W.; Gilmore, J.; Kamon, T.; Khotilovich, V.; Krutelyov, V.; Montalvo, R.; Osipenkov, I.; Pakhotin, Y.; Perloff, A.; Roe, J.; Rose, A.; Safonov, A.; Sakuma, T.; Suarez, I.; Tatarinov, A.; Akchurin, N.; Cowden, C.; Damgov, J.; Dragoiu, C.; Dudero, P. R.; Faulkner, J.; Kovitanggoon, K.; Kunori, S.; Lee, S. W.; Libeiro, T.; Volobouev, I.; Appelt, E.; Delannoy, A. G.; Greene, S.; Gurrola, A.; Johns, W.; Maguire, C.; Mao, Y.; Melo, A.; Sharma, M.; Sheldon, P.; Snook, B.; Tuo, S.; Velkovska, J.; Arenton, M. W.; Boutle, S.; Cox, B.; Francis, B.; Goodell, J.; Hirosky, R.; Ledovskoy, A.; Li, H.; Lin, C.; Neu, C.; Wood, J.; Gollapinni, S.; Harr, R.; Karchin, P. E.; Don, C. Kottachchi Kankanamge; Lamichhane, P.; Sturdy, J.; Belknap, D. A.; Carlsmith, D.; Cepeda, M.; Dasu, S.; Duric, S.; Friis, E.; Hall-Wilton, R.; Herndon, M.; Hervé, A.; Klabbers, P.; Lanaro, A.; Lazaridis, C.; Levine, A.; Loveless, R.; Mohapatra, A.; Ojalvo, I.; Perry, T.; Pierro, G. A.; Polese, G.; Ross, I.; Sarangi, T.; Savin, A.; Smith, W. H.; Woods, N.

    2014-09-01

    Production of prompt J/ ψ meson pairs in proton-proton collisions at = 7 TeV is measured with the CMS experiment at the LHC in a data sample corresponding to an integrated luminosity of about 4.7 fb-1. The two J/ ψ mesons are fully reconstructed via their decays into μ + μ - pairs. This observation provides for the first time access to the high-transverse-momentum region of J/ ψ pair production where model predictions are not yet established. The total and differential cross sections are measured in a phase space defined by the individual J/ ψ transverse momentum ( p T J/ ψ ) and rapidity (| y J/ ψ |): | y J/ ψ | < 1.2 for p {T/J/ ψ } > 6.5 GeV/ c; 1.2 < | y J/ ψ | < 1.43 for a p T threshold that scales linearly with | y J/ ψ | from 6.5 to 4.5 GeV/ c; and 1.43 < | y J/ ψ | < 2.2 for p {T/J/ ψ } > 4.5 GeV/ c. The total cross section, assuming unpolarized prompt J/ ψ pair production is 1.49 ± 0.07 (stat) ±0.13 (syst) nb. Different assumptions about the J/ ψ polarization imply modifications to the cross section ranging from -31% to +27%. [Figure not available: see fulltext.

  12. J-2X engine test

    NASA Image and Video Library

    2011-12-01

    NASA conducted a key stability test firing of the J-2X rocket engine on the A-2 Test Stand at Stennis Space Center on Dec. 1, marking another step forward in development of the upper-stage engine that will carry humans deeper into space than ever before. The J-2X will provide upper-stage power for NASA's new Space Launch System.

  13. Interview with J. Michael Thompson

    ERIC Educational Resources Information Center

    Randall, Mary Elisabeth

    2004-01-01

    J. Michael Thompson is the Vice Provost for Enrollment Management and Dean of Admission and Financial Aid at the University of Southern California. J. Michael has worked in higher education for more than 30 years in a variety of roles at small private and mid-sized and large public universities, and now at USC, a large private university. He has…

  14. Unique structural modulation of a non-native substrate by cochaperone DnaJ.

    PubMed

    Tiwari, Satyam; Kumar, Vignesh; Jayaraj, Gopal Gunanathan; Maiti, Souvik; Mapa, Koyeli

    2013-02-12

    The role of bacterial DnaJ protein as a cochaperone of DnaK is strongly appreciated. Although DnaJ unaccompanied by DnaK can bind unfolded as well as native substrate proteins, its role as an individual chaperone remains elusive. In this study, we demonstrate that DnaJ binds a model non-native substrate with a low nanomolar dissociation constant and, more importantly, modulates the structure of its non-native state. The structural modulation achieved by DnaJ is different compared to that achieved by the DnaK-DnaJ complex. The nature of structural modulation exerted by DnaJ is suggestive of a unique unfolding activity on the non-native substrate by the chaperone. Furthermore, we demonstrate that the zinc binding motif along with the C-terminal substrate binding domain of DnaJ is necessary and sufficient for binding and the subsequent binding-induced structural alterations of the non-native substrate. We hypothesize that this hitherto unknown structural alteration of non-native states by DnaJ might be important for its chaperoning activity by removing kinetic traps of the folding intermediates.

  15. Models of the strongly lensed quasar DES J0408-5354

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Agnello, A.; Lin, H.; Buckley-Geer, L.

    We present detailed modelling of the recently discovered, quadruply lensed quasar J0408-5354, with the aim of interpreting its remarkable configuration: besides three quasar images (A,B,D) around the main deflector (G1), a fourth image (C) is significantly reddened and dimmed by a perturber (G2) which is not detected in the Dark Energy Survey imaging data. From lens models incorporating (dust-corrected) flux ratios, we find a perturber Einstein radius 0.04 arcsec ≲ RE, G2 ≲ 0.2 arcsec and enclosed mass M p(R E, G2) ≲ 1.0 × 10 10 M⊙. The main deflector has stellar mass log10 (M */M⊙) =11.49more » $$+0.46\\atop{-0.32}$$ log10 (M */M⊙)=11.49-0.32+0.46 , a projected mass M p(R E, G1) ≈ 6 × 10 11 M⊙ within its Einstein radius R E, G1 = (1.85 ± 0.15) arcsec and predicted velocity dispersion 267–280 km s -1. Follow-up images from a companion monitoring campaign show additional components, including a candidate second source at a redshift between the quasar and G1. Models with free perturbers, and dust-corrected and delay-corrected flux ratios, are also explored. The predicted time-delays (Δt AB = (135.0 ± 12.6) d, Δt BD = (21.0 ± 3.5) d) roughly agree with those measured, but better imaging is required for proper modelling and comparison. Lastly, we also discuss some lessons learnt from J0408-5354 on lensed quasar finding strategies, due to its chromaticity and morphology.« less

  16. Models of the strongly lensed quasar DES J0408-5354

    DOE PAGES

    Agnello, A.; Lin, H.; Buckley-Geer, L.; ...

    2017-09-07

    We present detailed modelling of the recently discovered, quadruply lensed quasar J0408-5354, with the aim of interpreting its remarkable configuration: besides three quasar images (A,B,D) around the main deflector (G1), a fourth image (C) is significantly reddened and dimmed by a perturber (G2) which is not detected in the Dark Energy Survey imaging data. From lens models incorporating (dust-corrected) flux ratios, we find a perturber Einstein radius 0.04 arcsec ≲ RE, G2 ≲ 0.2 arcsec and enclosed mass M p(R E, G2) ≲ 1.0 × 10 10 M⊙. The main deflector has stellar mass log10 (M */M⊙) =11.49more » $$+0.46\\atop{-0.32}$$ log10 (M */M⊙)=11.49-0.32+0.46 , a projected mass M p(R E, G1) ≈ 6 × 10 11 M⊙ within its Einstein radius R E, G1 = (1.85 ± 0.15) arcsec and predicted velocity dispersion 267–280 km s -1. Follow-up images from a companion monitoring campaign show additional components, including a candidate second source at a redshift between the quasar and G1. Models with free perturbers, and dust-corrected and delay-corrected flux ratios, are also explored. The predicted time-delays (Δt AB = (135.0 ± 12.6) d, Δt BD = (21.0 ± 3.5) d) roughly agree with those measured, but better imaging is required for proper modelling and comparison. Lastly, we also discuss some lessons learnt from J0408-5354 on lensed quasar finding strategies, due to its chromaticity and morphology.« less

  17. Infection of porcine circovirus 2 (PCV2) in intestinal porcine epithelial cell line (IPEC-J2) and interaction between PCV2 and IPEC-J2 microfilaments.

    PubMed

    Yan, Mengfei; Zhu, Liqi; Yang, Qian

    2014-11-19

    Porcine circovirus-associated disease (PCVAD) is caused by a small pathogenic DNA virus, Porcine circovirus type 2 (PCV2), and is responsible for severe economic losses. PCV2-associated enteritis appears to be a distinct clinical manifestation of PCV2. Most studies of swine enteritis have been performed in animal infection models, but none have been conducted in vitro using cell lines of porcine intestinal origin. An in vitro system would be particularly useful for investigating microfilaments, which are likely to be involved in every stage of the viral lifecycle. We confirmed that PCV2 infects the intestinal porcine epithelial cell line IPEC-J2 by means of indirect immunofluorescence, transmission electron microscopy, flow cytometry and qRT-PCR. PCV2 influence on microfilaments in IPEC-J2 cells was detected by fluorescence microscopy and flow cytometry. We used Cytochalasin D or Cucurbitacin E to reorganize microfilaments, and observed changes in PCV2 invasion, replication and release in IPEC-J2 cells by qRT-PCR. PCV2 infection changes the ultrastructure of IPEC-J2 cells. PCV2 copy number in IPEC-J2 cells shows a rising trend as infection proceeds. Microfilaments are polymerized at 1 h p.i., but densely packed actin stress fibres are disrupted and total F-actin increases at 24, 48 and 72 h p.i. After Cytochalasin D treatment, invasion of PCV2 is suppressed, while invasion is facilitated by Cucurbitacin E. The microfilament drugs have opposite effects on viral release. PCV2 infects and proliferates in IPEC-J2 cells, demonstrating that IPEC-J2 cells can serve as a cell intestinal infection model for PCV2 pathogenesis. Furthermore, PCV2 rearranges IPEC-J2 microfilaments and increases the quantity of F-actin. Actin polymerization may facilitate the invasion of PCV2 in IPEC-J2 cells and the dissolution of cortical actin may promote PCV2 egress.

  18. CHANDRA OBSERVATIONS OF FIVE INTEGRAL SOURCES: NEW X-RAY POSITIONS FOR IGR J16393-4643 AND IGR J17091-3624

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bodaghee, A.; Tomsick, J. A.; Rahoui, F.

    2012-06-01

    The Chandra High Resolution Camera observed the fields of five hard X-ray sources in order to help us obtain X-ray coordinates with subarcsecond precision. These observations provide the most accurate X-ray positions known for IGR J16393-4643 and IGR J17091-3624. The obscured X-ray pulsar IGR J16393-4643 lies at R.A. (J2000) = 16{sup h}39{sup m}05.{sup s}47, and decl. = -46 Degree-Sign 42'13.''0 (error radius of 0.''6 at 90% confidence). This position is incompatible with the previously proposed counterpart 2MASS J16390535-4642137, and it points instead to a new counterpart candidate that is possibly blended with the Two Micron All Sky Survey star. Themore » black hole candidate IGR J17091-3624 was observed during its 2011 outburst providing coordinates of R.A. = 17{sup h}09{sup m}07.{sup s}59, and decl. = -36 Degree-Sign 24'25.''4. This position is compatible with those of the proposed optical/IR and radio counterparts, solidifying the source's status as a microquasar. Three targets, IGR J14043-6148, IGR J16358-4726, and IGR J17597-2201, were not detected. We obtained 3{sigma} upper limits of, respectively, 1.7, 1.8, and 1.5 Multiplication-Sign 10{sup -12} erg cm{sup -2} s{sup -1} on their 2-10 keV fluxes.« less

  19. Bio-jETI: a service integration, design, and provisioning platform for orchestrated bioinformatics processes.

    PubMed

    Margaria, Tiziana; Kubczak, Christian; Steffen, Bernhard

    2008-04-25

    With Bio-jETI, we introduce a service platform for interdisciplinary work on biological application domains and illustrate its use in a concrete application concerning statistical data processing in R and xcms for an LC/MS analysis of FAAH gene knockout. Bio-jETI uses the jABC environment for service-oriented modeling and design as a graphical process modeling tool and the jETI service integration technology for remote tool execution. As a service definition and provisioning platform, Bio-jETI has the potential to become a core technology in interdisciplinary service orchestration and technology transfer. Domain experts, like biologists not trained in computer science, directly define complex service orchestrations as process models and use efficient and complex bioinformatics tools in a simple and intuitive way.

  20. GeneFisher-P: variations of GeneFisher as processes in Bio-jETI

    PubMed Central

    Lamprecht, Anna-Lena; Margaria, Tiziana; Steffen, Bernhard; Sczyrba, Alexander; Hartmeier, Sven; Giegerich, Robert

    2008-01-01

    Background PCR primer design is an everyday, but not trivial task requiring state-of-the-art software. We describe the popular tool GeneFisher and explain its recent restructuring using workflow techniques. We apply a service-oriented approach to model and implement GeneFisher-P, a process-based version of the GeneFisher web application, as a part of the Bio-jETI platform for service modeling and execution. We show how to introduce a flexible process layer to meet the growing demand for improved user-friendliness and flexibility. Results Within Bio-jETI, we model the process using the jABC framework, a mature model-driven, service-oriented process definition platform. We encapsulate remote legacy tools and integrate web services using jETI, an extension of the jABC for seamless integration of remote resources as basic services, ready to be used in the process. Some of the basic services used by GeneFisher are in fact already provided as individual web services at BiBiServ and can be directly accessed. Others are legacy programs, and are made available to Bio-jETI via the jETI technology. The full power of service-based process orientation is required when more bioinformatics tools, available as web services or via jETI, lead to easy extensions or variations of the basic process. This concerns for instance variations of data retrieval or alignment tools as provided by the European Bioinformatics Institute (EBI). Conclusions The resulting service- and process-oriented GeneFisher-P demonstrates how basic services from heterogeneous sources can be easily orchestrated in the Bio-jETI platform and lead to a flexible family of specialized processes tailored to specific tasks. PMID:18460174

  1. Life or death by NFκB, Losartan promotes survival in dy2J/dy2J mouse of MDC1A

    PubMed Central

    Elbaz, M; Yanay, N; Laban, S; Rabie, M; Mitrani-Rosenbaum, S; Nevo, Y

    2015-01-01

    Inflammation and fibrosis are well-defined mechanisms involved in the pathogenesis of the incurable Laminin α2-deficient congenital muscular dystrophy (MDC1A), while apoptosis mechanism is barely discussed. Our previous study showed treatment with Losartan, an angiotensin II type I receptor antagonist, improved muscle strength and reduced fibrosis through transforming growth factor beta (TGF-β) and mitogen-activated protein kinases (MAPK) signaling inhibition in the dy2J/dy2J mouse model of MDC1A. Here we show for the first time that Losartan treatment up-regulates and shifts the nuclear factor kappa B (NFκB) signaling pathway to favor survival versus apoptosis/damage in this animal model. Losartan treatment was associated with significantly increased serum tumor necrosis factor alpha (TNF-α) level, p65 nuclei accumulation, and decreased muscle IκB-β protein level, indicating NFκB activation. Moreover, NFκB anti-apoptotic target genes TNF receptor-associated factor 1 (TRAF1), TNF receptor-associated factor 2 (TRAF2), cellular inhibitor of apoptosis (cIAP2), and Ferritin heavy chain (FTH1) were increased following Losartan treatment. Losartan induced protein expression toward a pro-survival profile as BCL-2 expression levels were increased and Caspase-3 expression levels were decreased. Muscle apoptosis reduction was further confirmed using terminal deoxynucleotidyltransferase-mediated dUTP nick end labeling (TUNEL) assay. Thus, along with TGF-β and MAPK signaling, NFκB serves as an important regulatory pathway which following Losartan treatment promotes survival in the dy2J/dy2J mouse model of MDC1A. PMID:25766329

  2. IPHAS J025827.88+635234.9 and IPHAS J051814.33+294113.0: Two probable eclipsing intermediate polars

    NASA Astrophysics Data System (ADS)

    Joshi, Arti; Pandey, Jeewan Chandra

    2018-04-01

    We present photometry in the R-band and linear polarimetry of two cataclysmic variables, namely IPHAS J025827.88 + 635234.9 and IPHAS J051814.33 + 294113.0. The data were obtained from 1-m class tele-scopes of the Aryabhatta Research Institute of Observational Sciences (ARIES; Nainital, India). In addition to the deep eclipse, strong short-period oscillations are also found. We derived a pulse period of (1203 ± 25) s for IPHAS J025827.88 + 635234.9 and (3277 ± 81) s for IPHAS J051814.33 + 294113.0. The presence of both orbital and spin modulations in these systems indicate that they belong to a class of intermediate polars. The full width at half depth of the eclipse is also found to be variable from epoch to epoch for IPHAS J025827.88 + 635234.9. The presence of a variable linear polarization of high value in these two sources indicates that these systems possess a strong magnetic field.

  3. Measurement of direct CP violation parameters in B± → J/ψK± and B± → J/ψπ± decays with 10.4 fb-1 of Tevatron data.

    PubMed

    Abazov, V M; Abbott, B; Acharya, B S; Adams, M; Adams, T; Agnew, J P; Alexeev, G D; Alkhazov, G; Alton, A; Askew, A; Atkins, S; Augsten, K; Avila, C; Badaud, F; Bagby, L; Baldin, B; Bandurin, D V; Banerjee, S; Barberis, E; Baringer, P; Bartlett, J F; Bassler, U; Bazterra, V; Bean, A; Beattie, M; Begalli, M; Bellantoni, L; Beri, S B; Bernardi, G; Bernhard, R; Bertram, I; Besançon, M; Beuselinck, R; Bhat, P C; Bhatia, S; Bhatnagar, V; Blazey, G; Blessing, S; Bloom, K; Boehnlein, A; Boline, D; Boos, E E; Borissov, G; Brandt, A; Brandt, O; Brock, R; Bross, A; Brown, D; Bu, X B; Buehler, M; Buescher, V; Bunichev, V; Burdin, S; Buszello, C P; Camacho-Pérez, E; Casey, B C K; Castilla-Valdez, H; Caughron, S; Chakrabarti, S; Chan, K M; Chandra, A; Chapon, E; Chen, G; Cho, S W; Choi, S; Choudhary, B; Cihangir, S; Claes, D; Clutter, J; Cooke, M; Cooper, W E; Corcoran, M; Couderc, F; Cousinou, M-C; Cutts, D; Das, A; Davies, G; de Jong, S J; De La Cruz-Burelo, E; Déliot, F; Demina, R; Denisov, D; Denisov, S P; Desai, S; Deterre, C; DeVaughan, K; Diehl, H T; Diesburg, M; Ding, P F; Dominguez, A; Dubey, A; Dudko, L V; Duperrin, A; Dutt, S; Eads, M; Edmunds, D; Ellison, J; Elvira, V D; Enari, Y; Evans, H; Evdokimov, V N; Feng, L; Ferbel, T; Fiedler, F; Filthaut, F; Fisher, W; Fisk, H E; Fortner, M; Fox, H; Fuess, S; Garbincius, P H; Garcia-Bellido, A; García-González, J A; Gavrilov, V; Geng, W; Gerber, C E; Gershtein, Y; Ginther, G; Golovanov, G; Grannis, P D; Greder, S; Greenlee, H; Grenier, G; Gris, Ph; Grivaz, J-F; Grohsjean, A; Grünendahl, S; Grünewald, M W; Guillemin, T; Gutierrez, G; Gutierrez, P; Haley, J; Han, L; Harder, K; Harel, A; Hart, B; Hauptman, J M; Hays, J; Head, T; Hebbeker, T; Hedin, D; Hegab, H; Heinson, A P; Heintz, U; Hensel, C; Heredia-De La Cruz, I; Herner, K; Hesketh, G; Hildreth, M D; Hirosky, R; Hoang, T; Hobbs, J D; Hoeneisen, B; Hogan, J; Hohlfeld, M; Howley, I; Hubacek, Z; Hynek, V; Iashvili, I; Ilchenko, Y; Illingworth, R; Ito, A S; Jabeen, S; Jaffré, M; Jayasinghe, A; Holzbauer, J; Jeong, M S; Jesik, R; Jiang, P; Johns, K; Johnson, E; Johnson, M; Jonckheere, A; Jonsson, P; Joshi, J; Jung, A W; Juste, A; Kajfasz, E; Karmanov, D; Katsanos, I; Kehoe, R; Kermiche, S; Khalatyan, N; Khanov, A; Kharchilava, A; Kharzheev, Y N; Kiselevich, I; Kohli, J M; Kozelov, A V; Kraus, J; Kumar, A; Kupco, A; Kurča, T; Kuzmin, V A; Lammers, S; Lamont, I; Lebrun, P; Lee, H S; Lee, S W; Lee, W M; Lei, X; Lellouch, J; Li, D; Li, H; Li, L; Li, Q Z; Lim, J K; Lincoln, D; Linnemann, J; Lipaev, V V; Lipton, R; Liu, H; Liu, Y; Lobodenko, A; Lokajicek, M; Lopes de Sa, R; Luna-Garcia, R; Lyon, A L; Maciel, A K A; Madar, R; Magaña-Villalba, R; Malik, S; Malyshev, V L; Mansour, J; Martínez-Ortega, J; Mason, N; McCarthy, R; McGivern, C L; Meijer, M M; Melnitchouk, A; Menezes, D; Mercadante, P G; Merkin, M; Meyer, A; Meyer, J; Miconi, F; Mondal, N K; Mulhearn, M; Nagy, E; Narain, M; Nayyar, R; Neal, H A; Negret, J P; Neustroev, P; Nguyen, H T; Nunnemann, T; Orduna, J; Osman, N; Osta, J; Pal, A; Parashar, N; Parihar, V; Park, S K; Partridge, R; Parua, N; Patwa, A; Penning, B; Perfilov, M; Peters, Y; Petridis, K; Petrillo, G; Pétroff, P; Pleier, M-A; Podstavkov, V M; Popov, A V; Prewitt, M; Price, D; Prokopenko, N; Qian, J; Quadt, A; Quinn, B; Ratoff, P N; Razumov, I; Ripp-Baudot, I; Rizatdinova, F; Rominsky, M; Ross, A; Royon, C; Rubinov, P; Ruchti, R; Sajot, G; Sánchez-Hernández, A; Sanders, M P; Santos, A S; Savage, G; Sawyer, L; Scanlon, T; Schamberger, R D; Scheglov, Y; Schellman, H; Schwanenberger, C; Schwienhorst, R; Sekaric, J; Severini, H; Shabalina, E; Shary, V; Shaw, S; Shchukin, A A; Simak, V; Skubic, P; Slattery, P; Smirnov, D; Snow, G R; Snow, J; Snyder, S; Söldner-Rembold, S; Sonnenschein, L; Soustruznik, K; Stark, J; Stoyanova, D A; Strauss, M; Suter, L; Svoisky, P; Titov, M; Tokmenin, V V; Tsai, Y-T; Tsybychev, D; Tuchming, B; Tully, C; Uvarov, L; Uvarov, S; Uzunyan, S; Van Kooten, R; van Leeuwen, W M; Varelas, N; Varnes, E W; Vasilyev, I A; Verkheev, A Y; Vertogradov, L S; Verzocchi, M; Vesterinen, M; Vilanova, D; Vokac, P; Wahl, H D; Wang, M H L S; Warchol, J; Watts, G; Wayne, M; Weichert, J; Welty-Rieger, L; Williams, M R J; Wilson, G W; Wobisch, M; Wood, D R; Wyatt, T R; Xie, Y; Yamada, R; Yang, S; Yasuda, T; Yatsunenko, Y A; Ye, W; Ye, Z; Yin, H; Yip, K; Youn, S W; Yu, J M; Zennamo, J; Zhao, T G; Zhou, B; Zhu, J; Zielinski, M; Zieminska, D; Zivkovic, L

    2013-06-14

    We present a measurement of the direct CP-violating charge asymmetry in B(±) mesons decaying to J/ψK(±) and J/ψπ(±) where J/ψ decays to μ(+) μ(-), using the full run II data set of 10.4 fb(-1) of proton-antiproton collisions collected using the D0 detector at the Fermilab Tevatron Collider. A difference in the yield of B(-) and B(+) mesons in these decays is found by fitting to the difference between their reconstructed invariant mass distributions resulting in asymmetries of A(J/ψK) = [0.59 ± 0.37]%, which is the most precise measurement to date, and A(J/ψπ) = [-4.2 ± 4.5]%. Both measurements are consistent with standard model predictions.

  4. PSRs J0248+6021 and J2240+5832: young pulsars in the northern Galactic plane: Discovery, timing, and gamma-ray observations

    DOE PAGES

    Theureau, G.; Parent, D.; Cognard, I.; ...

    2010-12-03

    Context. Pulsars PSR J0248+6021 (with a rotation period P = 217 ms and spin-down powermore » $$\\dot{E}$$ = 2.13 × 10 35 erg s -1) and PSR J2240+5832 (P = 140 ms, $$\\dot{E}$$ = 2.12 × 10 35 erg s -1) were discovered in 1997 with the Nançay radio telescope during a northern Galactic plane survey, using the Navy-Berkeley Pulsar Processor (NBPP) filter bank. The GeV gamma-ray pulsations from both were discovered using the Fermi Large Area Telescope. Aims. We characterize the neutron star emission using radio and gamma-ray observations, and explore the rich environment of PSR J0248+6021. Methods. Twelve years of radio timing data, including glitches, with steadily improved instrumentation, such as the Berkeley-Orleans-Nançay pulsar backend, and a gamma-ray data set 2.6 times larger than previously published allow detailed investigations of these pulsars. Radio polarization data allow comparison with the geometry inferred from gamma-ray emission models. Results. The two pulsars resemble each other in both radio and gamma-ray data. Both are rare in having a single gamma-ray pulse offset far from the radio peak. The anomalously high dispersion measure for PSR J0248+6021 (DM = 370 pc cm -3) is most likely due to its being within the dense, giant HII region W5 in the Perseus arm at a distance of 2 kpc, as opposed to being beyond the edge of the Galaxy as obtained from models of average electron distributions. Its large transverse velocity and the low magnetic field along the line-of-sight favor this small distance. Neither gamma-ray, X-ray, nor optical data yield evidence of a pulsar wind nebula surrounding PSR J0248+6021. We report the discovery of gamma-ray pulsations from PSR J2240+5832. We argue that it could be in the outer arm, although slightly nearer than its DM-derived distance, but that it may be in the Perseus arm at half the distance. Conclusions. The energy flux and distance yield a gamma-ray luminosity for PSR J0248+6021 of Lγ = (1.4 ± 0.3) × 10 34

  5. 75 FR 5704 - Proposed Modification of Jet Routes J-37 and J-55; Northeast United States

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-04

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 [Docket No. FAA-2010-0003; Airspace Docket No. 09-ANE-104] RIN 2120-AA66 Proposed Modification of Jet Routes J-37 and J-55; Northeast United States AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed...

  6. J-Resistance Curves of Aluminum Specimens Using Moire Interferometry

    DTIC Science & Technology

    1989-04-01

    elastic-plastic fracture mechanics ( EPFM ) methodologies are based on the J-integral or the crack opening displacement (COD) approach. The J-resistance curve...in the HRR field [13,141. In this paper, we present further application of the approximate J-evaluation procedure in large 2024-0 and 5052-H32 aluminum...Davis, J. A. Joyce, and R. A. Hays, " Application of the J-Integral and the Modified J-Integral to Cases of Large Crack Extension and High Toughness

  7. Determination of the number of J/ψ events with inclusive J/ψ decays

    NASA Astrophysics Data System (ADS)

    Ablikim, M.; Achasov, M. N.; Ai, X. C.; Albayrak, O.; Albrecht, M.; Ambrose, D. J.; Amoroso, A.; An, F. F.; An, Q.; Bai, J. Z.; Baldini Ferroli, R.; Ban, Y.; Bennett, D. W.; Bennett, J. V.; Bertani, M.; Bettoni, D.; Bian, J. M.; Bianchi, F.; Boger, E.; Boyko, I.; Briere, R. A.; Cai, H.; Cai, X.; Cakir, O.; Calcaterra, A.; Cao, G. F.; Cetin, S. A.; Chang, J. F.; Chelkov, G.; Chen, G.; Chen, H. S.; Chen, H. Y.; Chen, J. C.; Chen, M. L.; Chen, S. J.; Chen, X.; Chen, X. R.; Chen, Y. B.; Cheng, H. P.; Chu, X. K.; Cibinetto, G.; Dai, H. L.; Dai, J. P.; Dbeyssi, A.; Dedovich, D.; Deng, Z. Y.; Denig, A.; Denysenko, I.; Destefanis, M.; De Mori, F.; Ding, Y.; Dong, C.; Dong, J.; Dong, L. Y.; Dong, M. Y.; Dou, Z. L.; Du, S. X.; Duan, P. F.; Fan, J. Z.; Fang, J.; Fang, S. S.; Fang, X.; Fang, Y.; Farinelli, R.; Fava, L.; Fedorov, O.; Feldbauer, F.; Felici, G.; Feng, C. Q.; Fioravanti, E.; Fritsch, M.; Fu, C. D.; Gao, Q.; Gao, X. L.; Gao, X. Y.; Gao, Y.; Gao, Z.; Garzia, I.; Goetzen, K.; Gong, L.; Gong, W. X.; Gradl, W.; Greco, M.; Gu, M. H.; Gu, Y. T.; Guan, Y. H.; Guo, A. Q.; Guo, L. B.; Guo, Y.; Guo, Y. P.; Haddadi, Z.; Hafner, A.; Han, S.; Hao, X. Q.; Harris, F. A.; He, K. L.; Held, T.; Heng, Y. K.; Hou, Z. L.; Hu, C.; Hu, H. M.; Hu, J. F.; Hu, T.; Hu, Y.; Huang, G. S.; Huang, J. S.; Huang, X. T.; Huang, Y.; Hussain, T.; Ji, Q.; Ji, Q. P.; Ji, X. B.; Ji, X. L.; Jiang, L. W.; Jiang, X. S.; Jiang, X. Y.; Jiao, J. B.; Jiao, Z.; Jin, D. P.; Jin, S.; Johansson, T.; Julin, A.; Kalantar-Nayestanaki, N.; Kang, X. L.; Kang, X. S.; Kavatsyuk, M.; Ke, B. C.; Kiese, P.; Kliemt, R.; Kloss, B.; Kolcu, O. B.; Kopf, B.; Kornicer, M.; Kupsc, A.; Kühn, W.; Lange, J. S.; Lara, M.; Larin, P.; Leng, C.; Li, C.; Li, Cheng; Li, D. M.; Li, F.; Li, F. Y.; Li, G.; Li, H. B.; Li, J. C.; Li, Jin; Li, K.; Li, K.; Li, Lei; Li, P. R.; Li, Q. Y.; Li, T.; Li, W. D.; Li, W. G.; Li, X. L.; Li, X. N.; Li, X. Q.; Li, Z. B.; Liang, H.; Liang, Y. F.; Liang, Y. T.; Liao, G. R.; Lin, D. X.; Liu, B. J.; Liu, C. X.; Liu, D.; Liu, F. H.; Liu, Fang; Liu, Feng; Liu, H. B.; Liu, H. H.; Liu, H. H.; Liu, H. M.; Liu, J.; Liu, J. B.; Liu, J. P.; Liu, J. Y.; Liu, K.; Liu, K. Y.; Liu, L. D.; Liu, P. L.; Liu, Q.; Liu, S. B.; Liu, X.; Liu, Y. B.; Liu, Z. A.; Liu, Zhiqing; Loehner, H.; Lou, X. C.; Lu, H. J.; Lu, J. G.; Lu, Y.; Lu, Y. P.; Luo, C. L.; Luo, M. X.; Luo, T.; Luo, X. L.; Lyu, X. R.; Ma, F. C.; Ma, H. L.; Ma, L. L.; Ma, Q. M.; Ma, T.; Ma, X. N.; Ma, X. Y.; Ma, Y. M.; Maas, F. E.; Maggiora, M.; Mao, Y. J.; Mao, Z. P.; Marcello, S.; Messchendorp, J. G.; Min, J.; Min, T. J.; Mitchell, R. E.; Mo, X. H.; Mo, Y. J.; Morales Morales, C.; Muchnoi, N. Yu.; Muramatsu, H.; Nefedov, Y.; Nerling, F.; Nikolaev, I. B.; Ning, Z.; Nisar, S.; Niu, S. L.; Niu, X. Y.; Olsen, S. L.; Ouyang, Q.; Pacetti, S.; Pan, Y.; Patteri, P.; Pelizaeus, M.; Peng, H. P.; Peters, K.; Pettersson, J.; Ping, J. L.; Ping, R. G.; Poling, R.; Prasad, V.; Qi, H. R.; Qi, M.; Qian, S.; Qiao, C. F.; Qin, L. Q.; Qin, N.; Qin, X. S.; Qin, Z. H.; Qiu, J. F.; Rashid, K. H.; Redmer, C. F.; Ripka, M.; Rong, G.; Rosner, Ch.; Ruan, X. D.; Santoro, V.; Sarantsev, A.; Savrié, M.; Schoenning, K.; Schumann, S.; Shan, W.; Shao, M.; Shen, C. P.; Shen, P. X.; Shen, X. Y.; Sheng, H. Y.; Song, W. M.; Song, X. Y.; Sosio, S.; Spataro, S.; Sun, G. X.; Sun, J. F.; Sun, S. S.; Sun, Y. J.; Sun, Y. Z.; Sun, Z. J.; Sun, Z. T.; Tang, C. J.; Tang, X.; Tapan, I.; Thorndike, E. H.; Tiemens, M.; Ullrich, M.; Uman, I.; Varner, G. S.; Wang, B.; Wang, B. L.; Wang, D.; Wang, D. Y.; Wang, K.; Wang, L. L.; Wang, L. S.; Wang, M.; Wang, P.; Wang, P. L.; Wang, W.; Wang, W. P.; Wang, X. F.; Wang, Y. D.; Wang, Y. F.; Wang, Y. Q.; Wang, Z.; Wang, Z. G.; Wang, Z. H.; Wang, Z. Y.; Weber, T.; Wei, D. H.; Weidenkaff, P.; Wen, S. P.; Wiedner, U.; Wolke, M.; Wu, L. H.; Wu, Z.; Xia, L.; Xia, L. G.; Xia, Y.; Xiao, D.; Xiao, H.; Xiao, Z. J.; Xie, Y. G.; Xiu, Q. L.; Xu, G. F.; Xu, L.; Xu, Q. J.; Xu, Q. N.; Xu, X. P.; Yan, L.; Yan, W. B.; Yan, W. C.; Yan, Y. H.; Yang, H. J.; Yang, H. X.; Yang, L.; Yang, Y. X.; Ye, M.; Ye, M. H.; Yin, J. H.; Yu, B. X.; Yu, C. X.; Yu, J. S.; Yuan, C. Z.; Yuan, W. L.; Yuan, Y.; Yuncu, A.; Zafar, A. A.; Zallo, A.; Zeng, Y.; Zeng, Z.; Zhang, B. X.; Zhang, B. Y.; Zhang, C.; Zhang, C. C.; Zhang, D. H.; Zhang, H. H.; Zhang, H. Y.; Zhang, J. J.; Zhang, J. L.; Zhang, J. Q.; Zhang, J. W.; Zhang, J. Y.; Zhang, J. Z.; Zhang, K.; Zhang, L.; Zhang, X. Y.; Zhang, Y.; Zhang, Y. H.; Zhang, Y. N.; Zhang, Y. T.; Zhang, Yu; Zhang, Z. H.; Zhang, Z. P.; Zhang, Z. Y.; Zhao, G.; Zhao, J. W.; Zhao, J. Y.; Zhao, J. Z.; Zhao, Lei; Zhao, Ling; Zhao, M. G.; Zhao, Q.; Zhao, Q. W.; Zhao, S. J.; Zhao, T. C.; Zhao, Y. B.; Zhao, Z. G.; Zhemchugov, A.; Zheng, B.; Zheng, J. P.; Zheng, W. J.; Zheng, Y. H.; Zhong, B.; Zhou, L.; Zhou, X.; Zhou, X. K.; Zhou, X. R.; Zhou, X. Y.; Zhu, K.; Zhu, K. J.; Zhu, S.; Zhu, S. H.; Zhu, X. L.; Zhu, Y. C.; Zhu, Y. S.; Zhu, Z. A.; Zhuang, J.; Zotti, L.; Zou, B. S.; Zou, J. H.; BESIII Collaboration

    2017-01-01

    A measurement of the number of J/ψ events collected with the BESIII detector in 2009 and 2012 is performed using inclusive decays of the J/ψ. The number of J/ψ events taken in 2009 is recalculated to be (223.7 ± 1.4) × 106, which is in good agreement with the previous measurement, but with significantly improved precision due to improvements in the BESIII software. The number of J/ψ events taken in 2012 is determined to be (1086.9 ± 6.0) × 106. In total, the number of J/ψ events collected with the BESIII detector is measured to be (1310.6 ± 7.0) × 106, where the uncertainty is dominated by systematic effects and the statistical uncertainty is negligible. Supported by National Key Basic Research Program of China (2015CB856700), National Natural Science Foundation of China (NSFC) (10805053, 11125525, 11175188, 11235011, 11322544, 11335008, 11425524), Chinese Academy of Sciences (CAS) Large-Scale Scientific Facility Program, the CAS Center for Excellence in Particle Physics (CCEPP), Collaborative Innovation Center for Particles and Interactions (CICPI), Joint Large-Scale Scientific Facility Funds of NSFC and CAS (11179007, U1232201, U1232107, U1332201), CAS (KJCX2-YW-N29, KJCX2-YW-N45), 100 Talents Program of CAS, INPAC and Shanghai Key Laboratory for Particle Physics and Cosmology, German Research Foundation DFG (Collaborative Research Center CRC-1044), Istituto Nazionale di Fisica Nucleare, Italy; Ministry of Development of Turkey (DPT2006K-120470), Russian Foundation for Basic Research (14-07-91152), U. S. Department of Energy (DE-FG02-04ER41291, DE-FG02-05ER41374, DE-FG02-94ER40823, DESC0010118), U.S. National Science Foundation, University of Groningen (RuG) and the Helmholtzzentrum fuer Schwerionenforschung GmbH (GSI), Darmstadt; WCU Program of National Research Foundation of Korea (R32-2008-000-10155-0)

  8. j5 v2.8.4

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hillson, Nathan

    j5 automates and optimizes the design of the molecular biological process of cloning/constructing DNA. j5 enables users to benefit from (combinatorial) multi-part scar-less SLIC, Gibson, CPEC, Golden Gate assembly, or variants thereof, for which automation software does not currently exist, without the intense labor currently associated with the process. j5 inputs a list of the DNA sequences to be assembled, along with a Genbank, FASTA, jbei-seq, or SBOL v1.1 format sequence file for each DNA source. Given the list of DNA sequences to be assembled, j5 first determines the cost-minimizing assembly strategy for each part (direct synthesis, PCR/SOE, or oligo-embedding),more » designs DNA oligos with Primer3, adds flanking homology sequences (SLIC, Gibson, and CPEC; optimized with Primer3 for CPEC) or optimized overhang sequences (Golden Gate) to the oligos and direct synthesis pieces, and utilizes BLAST to check against oligo mis-priming and assembly piece incompatibility events. After identifying DNA oligos that are already contained within a local collection for reuse, the program estimates the total cost of direct synthesis and new oligos to be ordered. In the instance that j5 identifies putative assembly piece incompatibilities (multiple pieces with high flanking sequence homology), the program suggests hierarchical subassemblies where possible. The program outputs a comma-separated value (CSV) file, viewable via Excel or other spreadsheet software, that contains assembly design information (such as the PCR/SOE reactions to perform, their anticipated sizes and sequences, etc.) as well as a properly annotated genbank file containing the sequence resulting from the assembly, and appends the local oligo library with the oligos to be ordered j5 condenses multiple independent assembly projects into 96-well format for high-throughput liquid-handling robotics platforms, and generates configuration files for the PR-PR biology-friendly robot programming language. j5 thus

  9. Mean-field theory for multipole ordering in f-electron systems on the basis of a j-j coupling scheme

    NASA Astrophysics Data System (ADS)

    Yamamura, Ryosuke; Hotta, Takashi

    2018-05-01

    We develop a microscopic theory for multipole ordering, applicable to the system with plural numbers of f electrons per ion, from an itinerant picture on the basis of a j-j coupling scheme. For the purpose, by introducing the Γ8 Hubbard Hamiltonian as the minimum model to discuss the multipole ordering in f-electron systems, we describe the mean-field approximation in terms of the multipole operators. For the case of n = 2 , where n denotes the average f-electron number per ion, we analyze the model on a simple cubic lattice to obtain the multipole phase diagram. In particular, we find the order of non-Kramers Γ3 quadrupoles, O20 and O22 , with different ordering vectors. We attempt to explain the phase diagram from the discussion on the interaction energy.

  10. Hypothalamic expression of Peg3 gene is associated with maternal care differences between SM/J and LG/J mouse strains

    PubMed Central

    Chiavegatto, Silvana; Sauce, Bruno; Ambar, Guilherme; Cheverud, James M; Peripato, Andrea C

    2012-01-01

    Maternal care is essential in mammals, and variations in the environment provided by mothers may directly influence the viability of newborns and emotional behavior later in life. A previous study investigated genetic variations associated with maternal care in an intercross of LG/J and SM/J inbred mouse strains and identified two single-locus QTLs (quantitative trait loci). Here, we selected three candidate genes located within these QTLs intervals; Oxt on chromosome 2, and FosB and Peg3 on chromosome 7 and tested their association with maternal care. LG/J females showed impaired postpartum nest building and pup retrieval, a one-day delay in milk ejection, reduced exploratory activity, and higher anxiety-like behavior when compared to SM/J females. The nucleotide sequences of Oxt and FosB were similar between strains, as were their hypothalamic expression levels. Conversely, Peg3 nucleotide sequences showed four nonsynonymous replacement substitutions on LG/J dams, T11062G, G13744A, A13808G, and G13813A, and a 30 base pair (10 aa) in tandem repeat in the coding region with three copies in SM/J and five copies in LG/J. Maternal care impaired LG/J mothers express 37% lower Peg3 mRNA levels in the hypothalamus on the second postpartum day. We also found an association of the Peg3 repeat-variant and poor maternal care in F2 heterozygote females derived from a LG/J × SM/J intercross. These results may suggest that the maternally imprinted Peg3 gene is responsible for the single-locus QTL on chromosome 7 that has been shown to influence maternal care in these strains. Furthermore, these data provide additional support for an epigenetic regulation of maternal behavior. PMID:22950040

  11. Joint Chiefs of Staff > Directorates > J1 | Manpower and Personnel

    Science.gov Websites

    Management J1 | Manpower and Personnel J2 | Joint Staff Intelligence J3 | Operations J4 | Logistics► J8 | Force Structure, Resources & Assessment Contact J1 Manpower and Personnel Home : Directorates : J1 | Manpower and Personnel Mission To provide the Chairman of the Joint Chiefs of Staff

  12. The JBEI quantitative metabolic modeling library (jQMM): a python library for modeling microbial metabolism

    DOE PAGES

    Birkel, Garrett W.; Ghosh, Amit; Kumar, Vinay S.; ...

    2017-04-05

    Modeling of microbial metabolism is a topic of growing importance in biotechnology. Mathematical modeling helps provide a mechanistic understanding for the studied process, separating the main drivers from the circumstantial ones, bounding the outcomes of experiments and guiding engineering approaches. Among different modeling schemes, the quantification of intracellular metabolic fluxes (i.e. the rate of each reaction in cellular metabolism) is of particular interest for metabolic engineering because it describes how carbon and energy flow throughout the cell. In addition to flux analysis, new methods for the effective use of the ever more readily available and abundant -omics data (i.e. transcriptomics,more » proteomics and metabolomics) are urgently needed. The jQMM library presented here provides an open-source, Python-based framework for modeling internal metabolic fluxes and leveraging other -omics data for the scientific study of cellular metabolism and bioengineering purposes. Firstly, it presents a complete toolbox for simultaneously performing two different types of flux analysis that are typically disjoint: Flux Balance Analysis and 13C Metabolic Flux Analysis. Moreover, it introduces the capability to use 13C labeling experimental data to constrain comprehensive genome-scale models through a technique called two-scale 13C Metabolic Flux Analysis (2S- 13C MFA). In addition, the library includes a demonstration of a method that uses proteomics data to produce actionable insights to increase biofuel production. Finally, the use of the jQMM library is illustrated through the addition of several Jupyter notebook demonstration files that enhance reproducibility and provide the capability to be adapted to the user's specific needs. jQMM will facilitate the design and metabolic engineering of organisms for biofuels and other chemicals, as well as investigations of cellular metabolism and leveraging -omics data. As an open source software project, we hope it

  13. The JBEI quantitative metabolic modeling library (jQMM): a python library for modeling microbial metabolism

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Birkel, Garrett W.; Ghosh, Amit; Kumar, Vinay S.

    Modeling of microbial metabolism is a topic of growing importance in biotechnology. Mathematical modeling helps provide a mechanistic understanding for the studied process, separating the main drivers from the circumstantial ones, bounding the outcomes of experiments and guiding engineering approaches. Among different modeling schemes, the quantification of intracellular metabolic fluxes (i.e. the rate of each reaction in cellular metabolism) is of particular interest for metabolic engineering because it describes how carbon and energy flow throughout the cell. In addition to flux analysis, new methods for the effective use of the ever more readily available and abundant -omics data (i.e. transcriptomics,more » proteomics and metabolomics) are urgently needed. The jQMM library presented here provides an open-source, Python-based framework for modeling internal metabolic fluxes and leveraging other -omics data for the scientific study of cellular metabolism and bioengineering purposes. Firstly, it presents a complete toolbox for simultaneously performing two different types of flux analysis that are typically disjoint: Flux Balance Analysis and 13C Metabolic Flux Analysis. Moreover, it introduces the capability to use 13C labeling experimental data to constrain comprehensive genome-scale models through a technique called two-scale 13C Metabolic Flux Analysis (2S- 13C MFA). In addition, the library includes a demonstration of a method that uses proteomics data to produce actionable insights to increase biofuel production. Finally, the use of the jQMM library is illustrated through the addition of several Jupyter notebook demonstration files that enhance reproducibility and provide the capability to be adapted to the user's specific needs. jQMM will facilitate the design and metabolic engineering of organisms for biofuels and other chemicals, as well as investigations of cellular metabolism and leveraging -omics data. As an open source software project, we hope it

  14. MACS J0416.1-2403: Impact of line-of-sight structures on strong gravitational lensing modelling of galaxy clusters

    NASA Astrophysics Data System (ADS)

    Chirivì, G.; Suyu, S. H.; Grillo, C.; Halkola, A.; Balestra, I.; Caminha, G. B.; Mercurio, A.; Rosati, P.

    2018-06-01

    Exploiting the powerful tool of strong gravitational lensing by galaxy clusters to study the highest-redshift Universe and cluster mass distributions relies on precise lens mass modelling. In this work, we aim to present the first attempt at modelling line-of-sight (LOS) mass distribution in addition to that of the cluster, extending previous modelling techniques that assume mass distributions to be on a single lens plane. We have focussed on the Hubble Frontier Field cluster MACS J0416.1-2403, and our multi-plane model reproduces the observed image positions with a rms offset of 0.''53. Starting from this best-fitting model, we simulated a mock cluster that resembles MACS J0416.1-2403 in order to explore the effects of LOS structures on cluster mass modelling. By systematically analysing the mock cluster under different model assumptions, we find that neglecting the lensing environment has a significant impact on the reconstruction of image positions (rms 0.''3); accounting for LOS galaxies as if they were at the cluster redshift can partially reduce this offset. Moreover, foreground galaxies are more important to include into the model than the background ones. While the magnification factor of the lensed multiple images are recovered within 10% for 95% of them, those 5% that lie near critical curves can be significantly affected by the exclusion of the lensing environment in the models. In addition, LOS galaxies cannot explain the apparent discrepancy in the properties of massive sub-halos between MACS J0416.1-2403 and N-body simulated clusters. Since our model of MACS J0416.1-2403 with LOS galaxies only reduced modestly the rms offset in the image positions, we conclude that additional complexities would be needed in future models of MACS J0416.1-2403.

  15. J-2X engine

    NASA Image and Video Library

    2012-09-14

    NASA engineers continued to collect test performance data on the new J-2X rocket engine at Stennis Space Center with a 250-second test Sept. 14. The test on the A-2 Test Stand was the 19th in a series of firings to gather critical data for continued development of the engine. The J-2X is being developed by Pratt and Whitney Rocketdyne for NASA's Marshall Space Flight Center in Huntsville, Ala. It is the first liquid oxygen and liquid hydrogen rocket engine rated to carry humans into space to be developed in 40 years.

  16. Bio-jETI: a service integration, design, and provisioning platform for orchestrated bioinformatics processes

    PubMed Central

    Margaria, Tiziana; Kubczak, Christian; Steffen, Bernhard

    2008-01-01

    Background With Bio-jETI, we introduce a service platform for interdisciplinary work on biological application domains and illustrate its use in a concrete application concerning statistical data processing in R and xcms for an LC/MS analysis of FAAH gene knockout. Methods Bio-jETI uses the jABC environment for service-oriented modeling and design as a graphical process modeling tool and the jETI service integration technology for remote tool execution. Conclusions As a service definition and provisioning platform, Bio-jETI has the potential to become a core technology in interdisciplinary service orchestration and technology transfer. Domain experts, like biologists not trained in computer science, directly define complex service orchestrations as process models and use efficient and complex bioinformatics tools in a simple and intuitive way. PMID:18460173

  17. Joint Chiefs of Staff > Directorates > J3 | Operations

    Science.gov Websites

    Joint Staff Structure Joint Staff Inspector General Origin of Joint Concepts U.S. Code | Joint Chiefs of J8 | Force Structure, Resources & Assessment Contact J3 Operations Home : Directorates : J3

  18. The Splitting of Double-component Active Asteroid P/2016 J1 (PANSTARRS)

    NASA Astrophysics Data System (ADS)

    Moreno, F.; Pozuelos, F. J.; Novaković, B.; Licandro, J.; Cabrera-Lavers, A.; Bolin, Bryce; Jedicke, Robert; Gladman, Brett J.; Bannister, Michele T.; Gwyn, Stephen D. J.; Vereš, Peter; Chambers, Kenneth; Chastel, Serge; Denneau, Larry; Flewelling, Heather; Huber, Mark; Schunová-Lilly, Eva; Magnier, Eugene; Wainscoat, Richard; Waters, Christopher; Weryk, Robert; Farnocchia, Davide; Micheli, Marco

    2017-03-01

    We present deep imaging observations, orbital dynamics, and dust-tail model analyses of the double-component asteroid P/2016 J1 (J1-A and J1-B). The observations were acquired at the Gran Telescopio Canarias (GTC) and the Canada-France-Hawaii Telescope (CFHT) from mid-March to late July of 2016. A statistical analysis of backward-in-time integrations of the orbits of a large sample of clone objects of P/2016 J1-A and J1-B shows that the minimum separation between them occurred most likely ˜2300 days prior to the current perihelion passage, I.e., during the previous orbit near perihelion. This closest approach was probably linked to a fragmentation event of their parent body. Monte Carlo dust-tail models show that those two components became active simultaneously ˜250 days before the current perihelion, with comparable maximum loss rates of ˜0.7 and ˜0.5 kg s-1, and total ejected masses of 8 × 106 and 6 × 106 kg for fragments J1-A and J1-B, respectively. Consequently, the fragmentation event and the present dust activity are unrelated. The simultaneous activation times of the two components and the fact that the activity lasted 6-9 months or longer, strongly indicate ice sublimation as the most likely mechanism involved in the dust emission process.

  19. The Young L Dwarf 2MASS J11193254-1137466 Is a Planetary-mass Binary

    NASA Astrophysics Data System (ADS)

    Best, William M. J.; Liu, Michael C.; Dupuy, Trent J.; Magnier, Eugene A.

    2017-07-01

    We have discovered that the extremely red, low-gravity L7 dwarf 2MASS J11193254-1137466 is a 0.″14 (3.6 au) binary using Keck laser guide star adaptive optics imaging. 2MASS J11193254-1137466 has previously been identified as a likely member of the TW Hydrae Association (TWA). Using our updated photometric distance and proper motion, a kinematic analysis based on the BANYAN II model gives an 82% probability of TWA membership. At TWA’s 10 ± 3 Myr age and using hot-start evolutionary models, 2MASS J11193254-1137466AB is a pair of {3.7}-0.9+1.2 {M}{Jup} brown dwarfs, making it the lowest-mass binary discovered to date. We estimate an orbital period of {90}-50+80 years. One component is marginally brighter in K band but fainter in J band, making this a probable flux-reversal binary, the first discovered with such a young age. We also imaged the spectrally similar TWA L7 dwarf WISEA J114724.10-204021.3 with Keck and found no sign of binarity. Our evolutionary model-derived {T}{eff} estimate for WISEA J114724.10-204021.3 is ≈230 K higher than for 2MASS J11193254-1137466AB, at odds with the spectral similarity of the two objects. This discrepancy suggests that WISEA J114724.10-204021.3 may actually be a tight binary with masses and temperatures very similar to 2MASS J11193254-1137466AB, or further supporting the idea that near-infrared spectra of young ultracool dwarfs are shaped by factors other than temperature and gravity. 2MASS J11193254-1137466AB will be an essential benchmark for testing evolutionary and atmospheric models in the young planetary-mass regime.

  20. The J. Pedro Duret Mosquito Collection (Diptera: Culicidae)

    DTIC Science & Technology

    1990-12-01

    and a consultant for the Pan American Health Organiza- tion. The labels and collection records associated with the specimens bear ecological and...19 9 Holotype male: ൚.VII.64/Brasil/ Amazonas /J. Gou- lard/rio Preto/Col. DURET/[underside of label] 2275 / jHOLOTIPO//2275//Culex (Anoediop...Melanoconion). Holotype male: ൤.VI.63/Brasil/ Amazonas /Manaos/Col. Duret/ [undersideoflabel] 1940//HOLOTIPO//1940//Culex (Melanoc.)/faurani sp. n.jJ.P

  1. 30 CFR Appendix I to Subpart J of... - Appendix I to Subpart J of Part 7

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Appendix I to Subpart J of Part 7 I Appendix I to Subpart J of Part 7 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS TESTING BY APPLICANT OR THIRD PARTY Electric Motor...

  2. Heavy Ion Acceleration at J-PARC

    NASA Astrophysics Data System (ADS)

    SATO, Susumu

    2018-02-01

    J-PARC, the Japan Proton Accelerator Research Complex, is an accelerator, which provides a high-intensity proton beam. Recently as a very attractive project, the acceleration of heavy ions produced by supplementary ion sources, called J-PARC-HI, is seriously contemplated by domestic as well as international communities. The planned facility would accelerate heavy ions up to U92+ with a beam energy 20 AGeV ( of 6.2 AGeV). The highlight of the J-PARC-HI project is its very high beam rate up to 1011 Hz, which will enable the study of very rare events. Taking advantage of this high intensity, J-PARC-HI will carry out frontier studies of new and rare observables in this energy region: (i) nuclear medium modification of chiral property of vector mesons through low-mass di-lepton signal, (ii) QCD critical pointcharacterization through event-by-event fluctuation signals of particle production, (iii) systematic measurements related to the equation of state through collective flow signal or two-particle momentum correlation signal, or (iv) the search of hyper nuclei with multi strangeness including or exceeding S = 3. The current plan of J-PARC-HI aims to carrying out the first experimental measurements in 2025.

  3. Apolipoprotein J (clusterin) and Alzheimer's disease.

    PubMed

    Calero, M; Rostagno, A; Matsubara, E; Zlokovic, B; Frangione, B; Ghiso, J

    2000-08-15

    Apolipoprotein J (clusterin) is a ubiquitous multifunctional glycoprotein capable of interacting with a broad spectrum of molecules. In pathological conditions, it is an amyloid associated protein, co-localizing with fibrillar deposits in systemic and localized amyloid disorders. In Alzheimer's disease, the most frequent form of amyloidosis in humans and the major cause of dementia in the elderly, apoJ is present in amyloid plaques and cerebrovascular deposits but is rarely seen in NFT-containing neurons. ApoJ expression is up-regulated in a wide variety of insults and may represent a defense response against local damage to neurons. Four different mechanisms of action could be postulated to explain the role of apoJ as a neuroprotectant during cellular stress: (1) function as an anti-apoptotic signal, (2) protection against oxidative stress, (3) inhibition of the membrane attack complex of complement proteins locally activated as a result of inflammation, and (4) binding to hydrophobic regions of partially unfolded, stressed proteins, and therefore avoiding aggregation in a chaperone-like manner. This review focuses on the association of apoJ in biological fluids with Alzheimer's soluble Abeta. This interaction prevents Abeta aggregation and fibrillization and modulates its blood-brain barrier transport at the cerebrovascular endothelium. Copyright 2000 Wiley-Liss, Inc.

  4. Inhomogeneous Heisenberg spin chain and quantum vortex filament as non-holonomically deformed NLS systems

    NASA Astrophysics Data System (ADS)

    Abhinav, Kumar; Guha, Partha

    2018-03-01

    Through the Hasimoto map, various dynamical systems can be mapped to different integrodifferential generalizations of Nonlinear Schrödinger (NLS) family of equations some of which are known to be integrable. Two such continuum limits, corresponding to the inhomogeneous XXX Heisenberg spin chain [J. Phys. C 15, L1305 (1982)] and that of a thin vortex filament moving in a superfluid with drag [Eur. Phys. J. B 86, 275 (2013) 86; Phys. Rev. E 91, 053201 (2015)], are shown to be particular non-holonomic deformations (NHDs) of the standard NLS system involving generalized parameterizations. Crucially, such NHDs of the NLS system are restricted to specific spectral orders that exactly complements NHDs of the original physical systems. The specific non-holonomic constraints associated with these integrodifferential generalizations additionally posses distinct semi-classical signature.

  5. Pervasive and opposing effects of Unpredictable Chronic Mild Stress (UCMS) on hippocampal gene expression in BALB/cJ and C57BL/6J mouse strains.

    PubMed

    Malki, Karim; Mineur, Yann S; Tosto, Maria Grazia; Campbell, James; Karia, Priya; Jumabhoy, Irfan; Sluyter, Frans; Crusio, Wim E; Schalkwyk, Leonard C

    2015-04-03

    BALB/cJ is a strain susceptible to stress and extremely susceptible to a defective hedonic impact in response to chronic stressors. The strain offers much promise as an animal model for the study of stress related disorders. We present a comparative hippocampal gene expression study on the effects of unpredictable chronic mild stress on BALB/cJ and C57BL/6J mice. Affymetrix MOE 430 was used to measure hippocampal gene expression from 16 animals of two different strains (BALB/cJ and C57BL/6J) of both sexes and subjected to either unpredictable chronic mild stress (UCMS) or no stress. Differences were statistically evaluated through supervised and unsupervised linear modelling and using Weighted Gene Coexpression Network Analysis (WGCNA). In order to gain further understanding into mechanisms related to stress response, we cross-validated our results with a parallel study from the GENDEP project using WGCNA in a meta-analysis design. The effects of UCMS are visible through Principal Component Analysis which highlights the stress sensitivity of the BALB/cJ strain. A number of genes and gene networks related to stress response were uncovered including the Creb1 gene. WGCNA and pathway analysis revealed a gene network centered on Nfkb1. Results from the meta-analysis revealed a highly significant gene pathway centred on the Ubiquitin C (Ubc) gene. All pathways uncovered are associated with inflammation and immune response. The study investigated the molecular mechanisms underlying the response to adverse environment in an animal model using a GxE design. Stress-related differences were visible at the genomic level through PCA analysis highlighting the high sensitivity of BALB/cJ animals to environmental stressors. Several candidate genes and gene networks reported are associated with inflammation and neurogenesis and could serve to inform candidate gene selection in human studies and provide additional insight into the pathology of Major Depressive Disorder.

  6. Official portrait of astronaut Charles J. Precourt

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Official portrait of astronaut Charles J. Precourt. Precourt, a member of Astronaut Class 13 and United States Air Force (USAF), wears blue flight suit and poses with space shuttle orbiter model with a United States flag creating the backdrop.

  7. STS-47 Spacelab-J, Onboard Photograph

    NASA Technical Reports Server (NTRS)

    1992-01-01

    Japanese astronaut, Mamoru Mohri, talks to Japanese students from the aft flight deck of the Space Shuttle Orbiter Endeavour during the Spacelab-J (SL-J) mission. The SL-J mission was a joint venture between NASA and the National Space Development Agency of Japan (NASDA) utilizing a marned Spacelab module. The mission conducted 24 materials science and 20 life science experiments, of which 35 were sponsored by NASDA, 7 by NASA, and two collaborative efforts. Materials science investigations covered such fields as biotechnology, electronic materials, fluid dynamics and transport phenomena, glasses and ceramics, metals and alloys, and acceleration measurements. Life sciences included experiments on human health, cell separation and biology, developmental biology, animal and human physiology and behavior, space radiation, and biological rhythms. Test subjects included the crew, Japanese koi fish (carp), cultured animal and plant cells, chicken embryos, fruit flies, fungi and plant seeds, and frogs and frog eggs. Spacelab-J was launched aboard the Space Shuttle Orbiter Endeavour on September 12, 1992.

  8. Global analysis of DNA methylation in young (J1) and senescent (J2) Gossypium hirsutum L. cotyledons by MeDIP-Seq

    PubMed Central

    Dou, Lingling; Jia, Xiaoyun; Wei, Hengling; Fan, Shuli; Wang, Hantao; Guo, Yaning; Duan, Shan; Pang, Chaoyou; Yu, Shuxun

    2017-01-01

    DNA methylation is an important epigenetic modification regulating gene expression, genomic imprinting, transposon silencing and chromatin structure in plants and plays an important role in leaf senescence. However, the DNA methylation pattern during Gossypium hirsutum L. cotyledon senescence is poorly understood. In this study, global DNA methylation patterns were compared between two cotyledon development stages, young (J1) and senescence (J2), using methylated DNA immunoprecipitation (MeDIP-Seq). Methylated cytosine occurred mostly in repeat elements, especially LTR/Gypsy in both J1 and J2. When comparing J1 against J2, there were 1222 down-methylated genes and 623 up-methylated genes. Methylated genes were significantly enriched in carbohydrate metabolism, biosynthesis of other secondary metabolites and amino acid metabolism pathways. The global DNA methylation level decreased from J1 to J2, especially in gene promoters, transcriptional termination regions and regions around CpG islands. We further investigated the expression patterns of 9 DNA methyltransferase-associated genes and 2 DNA demethyltransferase-associated genes from young to senescent cotyledons, which were down-regulated during cotyledon development. In this paper, we first reported that senescent cotton cotyledons exhibited lower DNA methylation levels, primarily due to decreased DNA methyltransferase activity and which also play important role in regulating secondary metabolite process. PMID:28715427

  9. Energy metabolism in BPH/2J genetically hypertensive mice.

    PubMed

    Jackson, Kristy L; Nguyen-Huu, Thu-Phuc; Davern, Pamela J; Head, Geoffrey A

    2014-05-01

    Recent evidence indicates that genetic hypertension in BPH/2J mice is sympathetically mediated, but these mice also have lower body weight (BW) and elevated locomotor activity compared with BPN/3J normotensive mice, suggestive of metabolic abnormalities. The aim of the present study was to determine whether hypertension in BPH/2J mice is associated with metabolic differences. Whole-body metabolic and cardiovascular parameters were measured over 24 h by indirect calorimetry and radiotelemetry respectively, in conscious young (10-13 weeks) and older (22-23 weeks) BPH/2J, normotensive BPN/3J and C57Bl6 mice. Blood pressure (BP) was greater in BPH/2J compared with both normotensive strains at both ages (P<0.01). Metabolic rate was greater in young BPH/2J compared with BPN/3J mice (P<0.01) but similar to C57Bl6 mice indicating that high metabolic rate is not necessarily related to the hypertension per say. The slope of the BP-metabolic rate relationship was comparable between BPH/2J and normotensive mice when adjusted for activity (P>0.1) suggesting differences in this relationship are not responsible for hypertension. EchoMRI revealed that percentage body composition was comparable in BPN/3J and BPH/2J mice (P>0.1) and both strains gained weight similarly with age (P=0.3). Taken together, the present findings indicate that hypertension in BPH/2J mice does not appear to be related to altered energy metabolism.

  10. Branching fraction measurement of J / ψ → K S K L and search for J / ψ → K S K S

    DOE PAGES

    Ablikim, M.; Achasov, M. N.; Ahmed, S.; ...

    2017-12-04

    Using a sample of 1.31×10 9J/ψ events collected with the BESIII detector at the BEPCII collider, we study the decays of J/ψ→ K SK L and K SK S. The branching fraction of J/ψ→ K SK L is determined to be B(J/ψ→ K SK L) = (1:93 0:01 (stat:) 0:05 (syst:))×10 -4, which signi cantly improves on previous measurements. No clear signal is observed for the J/ψ→ K SK S process, and the upper limit at the 95% con dence level for its branching fraction is determined to be B(J= ! K SK S) < 1:4×10 -8, which improves onmore » the previous searches by 2 orders in magnitude and reaches the order of the Einstein-Podolsky-Rosen expectation.« less

  11. Branching fraction measurement of J / ψ → K S K L and search for J / ψ → K S K S

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ablikim, M.; Achasov, M. N.; Ahmed, S.

    Using a sample of 1.31×10 9J/ψ events collected with the BESIII detector at the BEPCII collider, we study the decays of J/ψ→ K SK L and K SK S. The branching fraction of J/ψ→ K SK L is determined to be B(J/ψ→ K SK L) = (1:93 0:01 (stat:) 0:05 (syst:))×10 -4, which signi cantly improves on previous measurements. No clear signal is observed for the J/ψ→ K SK S process, and the upper limit at the 95% con dence level for its branching fraction is determined to be B(J= ! K SK S) < 1:4×10 -8, which improves onmore » the previous searches by 2 orders in magnitude and reaches the order of the Einstein-Podolsky-Rosen expectation.« less

  12. The t J model for the oxide high-Tc superconductors

    NASA Astrophysics Data System (ADS)

    Ogata, Masao; Fukuyama, Hidetoshi

    2008-03-01

    A theoretical review is given on high temperature superconductivity in copper oxides (cuprates) by focusing on the hole doping cases based on the view that it is realized in carrier doped Mott insulators, as noted by Anderson in the initial stage. From the detailed knowledge of electronic states deduced from experiments that showed the undoped parent case is Mott insulators (charge transfer type insulators, to be precise) and that the hole doping is mainly on oxygen sites, the t-J model, as derived by Zhang and Rice, is shown to be a canonical model for hole doped cuprates and values of various parameters of the model have been assessed. Results of many different numerical methods so far obtained for this t-J model, especially the variational Monte Carlo method, have clearly indicated the stability of the \\rmd_{x^2-y^2} -wave superconductivity at absolute zero for the parameter region of actual experimental interest and the particular doping dependences of the condensation energy of superconductivity reflecting particular features of doped Mott insulators. For finite temperatures, on the other hand, the field theoretical slave-boson approximation based on the spin (spinons) and charge (holons) separations and the gauge fields as a glue combining them predicts qualitatively particular features of the existence of characteristic crossover temperatures of the spin singlet of the resonating valence bond (RVB) state, TRVB and the onset of Bose condensation of holons, TB, triggering coherent motion of electrons as convoluted particles of spinons and holons. The considerations based on the gauge field indicate that the onset temperature of superconductivity, Tc, is the lower one of these two, i.e. either TB (overdoped cases) or TRVB (underdoped cases), respectively. These characteristic features of the 'phase diagram' at finite temperatures are in overall agreement with various experimental observations, especially with the existence of spin-gap or pseudo-gap phases. In

  13. CryJ-LAMP DNA Vaccines for Japanese Red Cedar Allergy Induce Robust Th1-Type Immune Responses in Murine Model

    PubMed Central

    Connolly, Michael; Marketon, Anthony

    2016-01-01

    Allergies caused by Japanese Red Cedar (JRC) pollen affect up to a third of Japanese people, necessitating development of an effective therapeutic. We utilized the lysosomal targeting property of lysosomal-associated membrane protein-1 (LAMP-1) to make DNA vaccines that encode LAMP-1 and the sequences of immunodominant allergen CryJ1 or CryJ2 from the JRC pollen. This novel strategy is designed to skew the CD4 T cell responses to the target allergens towards a nonallergenic Th1 response. CryJ1-LAMP and CryJ2-LAMP were administrated to BALB/c mice and antigen-specific Th1-type IgG2a and Th2-type IgG1 antibodies, as well as IgE antibodies, were assayed longitudinally. We also isolated different T cell populations from immunized mice and adoptively transferred them into naïve mice followed by CryJ1/CryJ2 protein boosts. We demonstrated that CryJ-LAMP immunized mice produce high levels of IFN-γ and anti-CryJ1 or anti-CryJ2 IgG2a antibodies and low levels of IgE antibodies, suggesting that a Th1 response was induced. In addition, we found that CD4+ T cells are the immunological effectors of DNA vaccination in this allergy model. Together, our results suggest the CryJ-LAMP Vaccine has a potential as an effective therapeutic for JRC induced allergy by skewing Th1/Th2 responses. PMID:27239481

  14. Quantum-memory-assisted entropic uncertainty relation in a Heisenberg XYZ chain with an inhomogeneous magnetic field

    NASA Astrophysics Data System (ADS)

    Wang, Dong; Huang, Aijun; Ming, Fei; Sun, Wenyang; Lu, Heping; Liu, Chengcheng; Ye, Liu

    2017-06-01

    The uncertainty principle provides a nontrivial bound to expose the precision for the outcome of the measurement on a pair of incompatible observables in a quantum system. Therefore, it is of essential importance for quantum precision measurement in the area of quantum information processing. Herein, we investigate quantum-memory-assisted entropic uncertainty relation (QMA-EUR) in a two-qubit Heisenberg \\boldsymbol{X}\\boldsymbol{Y}\\boldsymbol{Z} spin chain. Specifically, we observe the dynamics of QMA-EUR in a realistic model there are two correlated sites linked by a thermal entanglement in the spin chain with an inhomogeneous magnetic field. It turns out that the temperature, the external inhomogeneous magnetic field and the field inhomogeneity can lift the uncertainty of the measurement due to the reduction of the thermal entanglement, and explicitly higher temperature, stronger magnetic field or larger inhomogeneity of the field can result in inflation of the uncertainty. Besides, it is found that there exists distinct dynamical behaviors of the uncertainty for ferromagnetism \\boldsymbol{}≤ft(\\boldsymbol{J}<\\boldsymbol{0}\\right) and antiferromagnetism \\boldsymbol{}≤ft(\\boldsymbol{J}>\\boldsymbol{0}\\right) chains. Moreover, we also verify that the measuring uncertainty is dramatically anti-correlated with the purity of the bipartite spin system, the greater purity can result in the reduction of the measuring uncertainty, vice versa. Therefore, our observations might provide a better understanding of the dynamics of the entropic uncertainty in the Heisenberg spin chain, and thus shed light on quantum precision measurement in the framework of versatile systems, particularly solid states.

  15. Richard J. French, Ph.D. | NREL

    Science.gov Websites

    J. French, Ph.D. Photo of Richard J. French Rick French Researcher IV-Chemistry Richard.French Laboratory equipment design and construction Computer-aided design (CAD) Education Ph.D., Chemistry, Oregon State University B.S., Chemistry, Wheaton College Professional Experience Research Scientist, National

  16. Heisenberg's observability principle

    NASA Astrophysics Data System (ADS)

    Wolff, Johanna

    2014-02-01

    Werner Heisenberg's 1925 paper 'Quantum-theoretical re-interpretation of kinematic and mechanical relations' marks the beginning of quantum mechanics. Heisenberg famously claims that the paper is based on the idea that the new quantum mechanics should be 'founded exclusively upon relationships between quantities which in principle are observable'. My paper is an attempt to understand this observability principle, and to see whether its employment is philosophically defensible. Against interpretations of 'observability' along empiricist or positivist lines I argue that such readings are philosophically unsatisfying. Moreover, a careful comparison of Heisenberg's reinterpretation of classical kinematics with Einstein's argument against absolute simultaneity reveals that the positivist reading does not fit with Heisenberg's strategy in the paper. Instead the appeal to observability should be understood as a specific criticism of the causal inefficacy of orbital electron motion in Bohr's atomic model. I conclude that the tacit philosophical principle behind Heisenberg's argument is not a positivistic connection between observability and meaning, but the idea that a theory should not contain causally idle wheels.

  17. Effective One-Dimensional Coupling in the Highly Frustrated Square-Lattice Itinerant Magnet CaCo2 -yAs2

    NASA Astrophysics Data System (ADS)

    Sapkota, A.; Ueland, B. G.; Anand, V. K.; Sangeetha, N. S.; Abernathy, D. L.; Stone, M. B.; Niedziela, J. L.; Johnston, D. C.; Kreyssig, A.; Goldman, A. I.; McQueeney, R. J.

    2017-10-01

    Inelastic neutron scattering measurements on the itinerant antiferromagnet CaCo2 -yAs2 at a temperature of 8 K reveal two orthogonal planes of scattering perpendicular to the Co square lattice in reciprocal space, demonstrating the presence of effective one-dimensional spin interactions. These results are shown to arise from near-perfect bond frustration within the J1-J2 Heisenberg model on a square lattice with ferromagnetic J1 and hence indicate that the extensive previous experimental and theoretical study of the J1-J2 Heisenberg model on local-moment square spin lattices should be expanded to include itinerant spin systems.

  18. Effective One-Dimensional Coupling in the Highly Frustrated Square-Lattice Itinerant Magnet CaCo_{2-y}As_{2}.

    PubMed

    Sapkota, A; Ueland, B G; Anand, V K; Sangeetha, N S; Abernathy, D L; Stone, M B; Niedziela, J L; Johnston, D C; Kreyssig, A; Goldman, A I; McQueeney, R J

    2017-10-06

    Inelastic neutron scattering measurements on the itinerant antiferromagnet CaCo_{2-y}As_{2} at a temperature of 8 K reveal two orthogonal planes of scattering perpendicular to the Co square lattice in reciprocal space, demonstrating the presence of effective one-dimensional spin interactions. These results are shown to arise from near-perfect bond frustration within the J_{1}-J_{2} Heisenberg model on a square lattice with ferromagnetic J_{1} and hence indicate that the extensive previous experimental and theoretical study of the J_{1}-J_{2} Heisenberg model on local-moment square spin lattices should be expanded to include itinerant spin systems.

  19. Effective One-Dimensional Coupling in the Highly Frustrated Square-Lattice Itinerant Magnet CaCo 2 - y As 2

    DOE PAGES

    Sapkota, A.; Ueland, B. G.; Anand, V. K.; ...

    2017-10-02

    Inelastic neutron scattering measurements on the itinerant antiferromagnet CaCo 2–yAs 2 at a temperature of 8 K reveal two orthogonal planes of scattering perpendicular to the Co square lattice in reciprocal space, demonstrating the presence of effective one-dimensional spin interactions. Here, these results are shown to arise from near-perfect bond frustration within the J 1–J 2 Heisenberg model on a square lattice with ferromagnetic J 1 and hence indicate that the extensive previous experimental and theoretical study of the J 1–J 2 Heisenberg model on local-moment square spin lattices should be expanded to include itinerant spin systems.

  20. Effective One-Dimensional Coupling in the Highly Frustrated Square-Lattice Itinerant Magnet CaCo 2 - y As 2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sapkota, A.; Ueland, B. G.; Anand, V. K.

    Inelastic neutron scattering measurements on the itinerant antiferromagnet CaCo 2–yAs 2 at a temperature of 8 K reveal two orthogonal planes of scattering perpendicular to the Co square lattice in reciprocal space, demonstrating the presence of effective one-dimensional spin interactions. Here, these results are shown to arise from near-perfect bond frustration within the J 1–J 2 Heisenberg model on a square lattice with ferromagnetic J 1 and hence indicate that the extensive previous experimental and theoretical study of the J 1–J 2 Heisenberg model on local-moment square spin lattices should be expanded to include itinerant spin systems.

  1. Contribution of Orexin to the Neurogenic Hypertension in BPH/2J Mice.

    PubMed

    Jackson, Kristy L; Dampney, Bruno W; Moretti, John-Luis; Stevenson, Emily R; Davern, Pamela J; Carrive, Pascal; Head, Geoffrey A

    2016-05-01

    BPH/2J mice are a genetic model of hypertension associated with an overactive sympathetic nervous system. Orexin is a neuropeptide which influences sympathetic activity and blood pressure. Orexin precursor mRNA expression is greater in hypothalamic tissue of BPH/2J compared with normotensive BPN/3J mice. To determine whether enhanced orexinergic signaling contributes to the hypertension, BPH/2J and BPN/3J mice were preimplanted with radiotelemetry probes to compare blood pressure 1 hour before and 5 hours after administration of almorexant, an orexin receptor antagonist. Mid frequency mean arterial pressure power and the depressor response to ganglion blockade were also used as indicators of sympathetic nervous system activity. Administration of almorexant at 100 (IP) and 300 mg/kg (oral) in BPH/2J mice during the dark-active period (2 hours after lights off) markedly reduced blood pressure (-16.1 ± 1.6 and -11.0 ± 1.1 mm Hg, respectively;P<0.001 compared with vehicle). However, when almorexant (100 mg/kg, IP) was administered during the light-inactive period (5 hours before lights off) no reduction from baseline was observed (P=0.64). The same dose of almorexant in BPN/3J mice had no effect on blood pressure during the dark (P=0.79) or light periods (P=0.24). Almorexant attenuated the depressor response to ganglion blockade (P=0.018) and reduced the mid frequency mean arterial pressure power in BPH/2J mice (P<0.001), but not BPN/3J mice (P=0.70). Immunohistochemical labeling revealed that BPH/2J mice have 29% more orexin neurons than BPN/3J mice which are preferentially located in the lateral hypothalamus. The results suggest that enhanced orexinergic signaling contributes to sympathetic overactivity and hypertension during the dark period in BPH/2J mice. © 2016 American Heart Association, Inc.

  2. The Splitting of Double-component Active Asteroid P/2016 J1 (PANSTARRS)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moreno, F.; Pozuelos, F. J.; Novaković, B.

    We present deep imaging observations, orbital dynamics, and dust-tail model analyses of the double-component asteroid P/2016 J1 (J1-A and J1-B). The observations were acquired at the Gran Telescopio Canarias (GTC) and the Canada–France–Hawaii Telescope (CFHT) from mid-March to late July of 2016. A statistical analysis of backward-in-time integrations of the orbits of a large sample of clone objects of P/2016 J1-A and J1-B shows that the minimum separation between them occurred most likely ∼2300 days prior to the current perihelion passage, i.e., during the previous orbit near perihelion. This closest approach was probably linked to a fragmentation event of theirmore » parent body. Monte Carlo dust-tail models show that those two components became active simultaneously ∼250 days before the current perihelion, with comparable maximum loss rates of ∼0.7 and ∼0.5 kg s{sup −1}, and total ejected masses of 8 × 10{sup 6} and 6 × 10{sup 6} kg for fragments J1-A and J1-B, respectively. Consequently, the fragmentation event and the present dust activity are unrelated. The simultaneous activation times of the two components and the fact that the activity lasted 6–9 months or longer, strongly indicate ice sublimation as the most likely mechanism involved in the dust emission process.« less

  3. STS-47 Spacelab-J, Onboard Photograph

    NASA Technical Reports Server (NTRS)

    1992-01-01

    The Spacelab-J (SL-J) mission was a joint venture between NASA and the National Space Development Agency of Japan (NASDA) utilizing a marned Spacelab module. Materials science investigations covered such fields as biotechnology, electronic materials, fluid dynamics and transport phenomena, glasses and ceramics, metals and alloys, and acceleration measurements. Life sciences included experiments on human health, cell separation and biology, developmental biology, animal and human physiology and behavior, space radiation, and biological rhythms. Before long-term space ventures are attempted, numerous questions must be answered: how will gravity play in the early development of an organism, and how will new generations of a species be conceived and develop normally in microgravity. The Effects of Weightlessness on the Development of Amphibian Eggs Fertilized in Space experiment aboard SL-J examined aspects of these questions. To investigate the effect of microgravity on amphibian development, female frogs carried aboard SL-J were induced to ovulate and shed eggs. These eggs were then fertilized in the microgravity environment. Half were incubated in microgravity, while the other half were incubated in a centrifuge that spins to simulate normal gravity. This photograph shows an astronaut working with one of the adult female frogs inside the incubator. The mission also examined the swimming behavior of tadpoles grown in the absence of gravity. The Spacelab-J was launched aboard the Space Shuttle Orbiter Endeavour on September 12, 1992.

  4. Fermi LAT Detection of Pulsed Gamma-Rays From the Vela-Like Pulsars PSR J1048-5832 and PSR J2229+6114

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Abdo, A.A.; /Naval Research Lab, Wash., D.C. /Federal City Coll.; Ackermann, M.

    We report the detection of {gamma}-ray pulsations ({ge}0.1 GeV) from PSR J2229+6114 and PSR J1048-5832, the latter having been detected as a low-significance pulsar by EGRET. Data in the {gamma}-ray band were acquired by the Large Area Telescope (LAT) aboard the Fermi Gamma-ray Space Telescope, while the radio rotational ephemerides used to fold the {gamma}-ray light curves were obtained using the Green Bank Telescope, the Lovell telescope at Jodrell Bank, and the Parkes Telescope. The two young radio pulsars, located within the error circles of the previously unidentified EGRET sources 3EG J1048-5840 and 3EG J2227+6122, present spin-down characteristics similar tomore » the Vela pulsar. PSR J1048-5832 shows two sharp peaks at phases 0.15 {+-} 0.01 and 0.57 {+-} 0.01 relative to the radio pulse confirming the EGRET light curve, while PSR J2229+6114 presents a very broad peak at phase 0.49 {+-} 0.01. The {gamma}-ray spectra above 0.1 GeV of both pulsars are fit with power laws having exponential cutoffs near 3 GeV, leading to integral photon fluxes of (2.19 {+-} 0.22 {+-} 0.32) x 10{sup -7} cm{sup -2} s{sup -1} for PSR J1048-5832 and (3.77 {+-} 0.22 {+-} 0.44) x 10{sup -7} cm{sup -2} s{sup -1} for PSR J2229+6114. The first uncertainty is statistical and the second is systematic. PSR J1048-5832 is one of the two LAT sources which were entangled together as 3EG J1048-5840. These detections add to the growing number of young {gamma}-ray pulsars that make up the dominant population of GeV {gamma}-ray sources in the Galactic plane.« less

  5. Swift observation of Nova Ophiuchi 2018 No.2 = PNV J17140261-2849237 = TCP J17140253-2849233

    NASA Astrophysics Data System (ADS)

    Sokolovsky, K.

    2018-03-01

    The nova candidate PNV J17140261-2849237 = TCP J17140253-2849233 was discovered by H. Nishimura, T. Kojima, K. Nishiyama and F. Kabashima. A. Takao reports the transient (9.5mag) visible at unfiltered images obtained on 2018-03-10.753 UT. Spectroscopic observations with the 2m Liverpool Telescope confirmed the transient to be a Fe II type nova (ATel #11398).

  6. Differences in cocaine-induced place preference persistence, locomotion and social behaviors between C57BL/6J and BALB/cJ mice

    PubMed Central

    WANG, Jian-Li; WANG, Bei; CHEN, Wen

    2014-01-01

    C57BL/6J and BALB/cJ mice display significant differences in sociability and response to drugs, but the phenotypic variability of their susceptibility to cocaine is still not well known. In this study, the differences between these two mice strains in the persistence of cocaine-induced conditioned place preference (CPP), as well as the locomotion and social behaviors after the 24-hour withdrawal from a four-day cocaine (20 mg/kg/day) administration were investigated. The results showed that the cocaine-induced CPP persisted over two weeks in C57BL/6J mice, while it diminished within one week among BALB/cJ mice. After 24-hours of cocaine withdrawal, high levels of locomotion as well as low levels of social interaction and aggressive behavior were found in C57BL/6J mice, but no significant changes were found in BALB/cJ mice, indicating that cocaine-induced CPP persistence, locomotion and social behavior are not consistent between these two strains, and that overall C57BL/6J mice are more susceptible to cocaine than BALB/cJ mice at the tested doses. PMID:25297083

  7. Differences in cocaine-induced place preference persistence, locomotion and social behaviors between C57BL/6J and BALB/cJ mice.

    PubMed

    Wang, Jian-Li; Wang, Bei; Chen, Wen

    2014-09-01

    C57BL/6J and BALB/cJ mice display significant differences in sociability and response to drugs, but the phenotypic variability of their susceptibility to cocaine is still not well known. In this study, the differences between these two mice strains in the persistence of cocaine-induced conditioned place preference (CPP), as well as the locomotion and social behaviors after the 24-hour withdrawal from a four-day cocaine (20 mg/kg/day) administration were investigated. The results showed that the cocaine-induced CPP persisted over two weeks in C57BL/6J mice, while it diminished within one week among BALB/cJ mice. After 24-hours of cocaine withdrawal, high levels of locomotion as well as low levels of social interaction and aggressive behavior were found in C57BL/6J mice, but no significant changes were found in BALB/cJ mice, indicating that cocaine-induced CPP persistence, locomotion and social behavior are not consistent between these two strains, and that overall C57BL/6J mice are more susceptible to cocaine than BALB/cJ mice at the tested doses.

  8. 22 CFR 505.13 - General exemptions (Subsection (j)).

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true General exemptions (Subsection (j)). 505.13... exemptions (Subsection (j)). (a) General exemptions are available for systems of records which are maintained by the Central Intelligence Agency (Subsection (j)(1)), or maintained by an agency which performs as...

  9. Driving missing data at the LHC: NNLO predictions for the ratio of γ + j and Z + j

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Campbell, John M.; Ellis, R. Keith; Williams, Ciaran

    In this paper we present a calculation of themore » $$\\gamma+j$$ process at next-to-next-to-leading order (NNLO) in QCD and compare the resulting predictions to 8 TeV CMS data. We find good agreement with the shape of the photon $$p_T$$ spectrum, particularly after the inclusion of additional electroweak corrections, but there is a tension between the overall normalization of the theoretical prediction and the measurement. We use our results to compute the ratio of $$Z(\\to \\ell^+\\ell^-)+j$$ to $$\\gamma+j$$ events as a function of the vector boson transverse momentum at NNLO, a quantity that is used to normalize $$Z(\\rightarrow\

  10. Staff - Gabriel J. Wolken | Alaska Division of Geological & Geophysical

    Science.gov Websites

    Facebook DGGS News Natural Resources Geological & Geophysical Surveys Staff - Gabriel J. Wolken main content Gabriel J. Wolken Gabriel J. Wolken Glaciology, climatology, geomorphology, snow science, geologic ., 2014, Arctic glaciers and ice caps (outside Greenland), in Blunden, J. and Arndt, D.S., eds., State of

  11. J/ψ polarization in p + p collisions at √s = 200 GeV in STAR

    DOE PAGES

    Adamczyk, L.

    2014-10-30

    The study report on a polarization measurement of inclusive J/ψ mesons in the di-electron decay channel at mid-rapidity at 2T<6 GeV/c in p+p collisions at √s = 200 GeV. Data were taken with the STAR detector at RHIC. The J/ψ polarization measurement should help to distinguish between different models of the J/ψ production mechanism since they predict different p T dependences of the J/ψ polarization. In this analysis, J/ψ polarization is studied in the helicity frame. The polarization parameter λ θ measured at RHIC becomes smaller towards high p T, indicating more longitudinal J/ψ polarization as p T increases. Themore » result is compared with predictions of presently available models.« less

  12. Measurement of Γee(J /ψ) with KEDR detector

    NASA Astrophysics Data System (ADS)

    Anashin, V. V.; Aulchenko, V. M.; Baldin, E. M.; Barladyan, A. K.; Barnyakov, A. Y.; Barnyakov, M. Y.; Baru, S. E.; Bedny, I. V.; Blinov, A. E.; Blinov, V. E.; Bobrov, A. V.; Bobrovnikov, V. S.; Bogomyagkov, A. V.; Bondar, A. E.; Bondarev, D. V.; Buzykaev, A. R.; Eidelman, S. I.; Glukhovchenko, Y. M.; Gulevich, V. V.; Gusev, D. V.; Karnaev, S. E.; Karpov, G. V.; Karpov, S. V.; Kharlamova, T. A.; Kiselev, V. A.; Kononov, S. A.; Kotov, K. Y.; Kravchenko, E. A.; Kulikov, V. F.; Kurkin, G. Y.; Kuper, E. A.; Levichev, E. B.; Maksimov, D. A.; Malyshev, V. M.; Maslennikov, A. L.; Medvedko, A. S.; Meshkov, O. I.; Mishnev, S. I.; Morozov, I. I.; Muchnoi, N. Y.; Neufeld, V. V.; Nikitin, S. A.; Nikolaev, I. B.; Okunev, I. N.; Onuchin, A. P.; Oreshkin, S. B.; Orlov, I. O.; Osipov, A. A.; Peleganchuk, S. V.; Pivovarov, S. G.; Piminov, P. A.; Petrov, V. V.; Poluektov, A. O.; Popkov, I. N.; Prisekin, V. G.; Rezanova, O. L.; Ruban, A. A.; Sandyrev, V. K.; Savinov, G. A.; Shamov, A. G.; Shatilov, D. N.; Shwartz, B. A.; Simonov, E. A.; Sinyatkin, S. V.; Skovpen, Y. I.; Skrinsky, A. N.; Smaluk, V. V.; Sokolov, A. V.; Sukharev, A. M.; Starostina, E. V.; Talyshev, A. A.; Tayursky, V. A.; Telnov, V. I.; Tikhonov, Y. A.; Todyshev, K. Y.; Tumaikin, G. M.; Usov, Y. V.; Vorobiov, A. I.; Yushkov, A. N.; Zhilich, V. N.; Zhulanov, V. V.; Zhuravlev, A. N.

    2018-05-01

    The product of the electronic width of the J/ψ meson and the branching fractions of its decay to hadrons and electrons has been measured using the KEDR detector at the VEPP-4M e + e - collider. The obtained values are Γ_{ee}(J/ψ )=5.550± 0.056± 0.089 Γ_{ee}(J/ψ )\\cdotp B_{hadrons}(J/ψ )=4.884± 0.048± 0.078 keV Γ_{ee}(J/ψ )\\cdotp B_{ee}(J/ψ )=0.3331± 0.0066± 0.0040 keV. The uncertainties shown are statistical and systematic, respectively. Using the result presented and the world-average value of the electronic branching fraction, one obtains the total width of the J/ψ meson: Γ =92.94± 1.83keV. These results are consistent with the previous experiments.

  13. Association of Escherichia coli J5-specific serum antibody responses with clinical mastitis outcome for J5 vaccinate and control dairy cattle.

    PubMed

    Wilson, David J; Mallard, Bonnie A; Burton, Jeanne L; Schukken, Ynte H; Grohn, Yrjo T

    2009-02-01

    Dairy cattle in two commercial Holstein herds were randomly selected to be vaccinated twice with J5, at approximately 60 days and 28 days before the expected calving date, or to be untreated controls. Based on whether milk production changed following clinical mastitis or whether cows were culled or died within 30 days after onset, 51 mastitis cases were classified as severe or mild. J5-specific antibody responses were evaluated by enzyme-linked immunosorbent assay of all 32 severe and 19 mild cases. The amounts of J5-specific immunoglobulin M (IgM), IgG1, and IgG2 antibodies in sera from the 27 J5 vaccinates were compared with those of the 24 controls. At drying off (before J5 vaccination), all cows had similar amounts of J5-specific antibody. Immediately after calving (approximately 28 days after the second vaccination), J5 vaccinates had significantly higher production of J5-specific IgG1 and IgG2 than controls. When cows were tested following clinical mastitis, none of the three antibody classes differed significantly between the controls and the vaccinates. Vaccinates that contracted Escherichia coli mastitis had 75% less milk loss than controls. The cows that contracted clinical mastitis later in lactation, the unvaccinated controls, and those infected with E. coli had more milk loss following mastitis. The hazards of being culled for all reasons and of being culled for mastitis were significantly lower for J5 vaccinates. Vaccination with J5 was associated with protection against milk production loss and culling following clinical mastitis, and it was also significantly associated with changes in J5-specific IgM, IgG1, and IgG2 antibodies in sera of vaccinated cows.

  14. Unveiling the radio counterparts of two binary AGN candidates: J1108+0659 and J1131-0204

    NASA Astrophysics Data System (ADS)

    Bondi, M.; Pérez-Torres, M. A.; Piconcelli, E.; Fu, H.

    2016-04-01

    The sources SDSS J113126.08-020459.2 and SDSS J110851.04+065901.4 are two double-peaked [O III] emitting active galactic nuclei (AGNs), identified as candidate binary AGNs by optical and near infrared (NIR) observations. We observed the two sources with high resolution Very Long Baseline Interferometry (VLBI) using the European VLBI Network at 5 GHz, reduced VLA observations at three frequencies available for one of the sources, and used archival HST observations. For the source SDSS J113126.08-020459.2, the VLBI observations detected only one single compact component associated with the eastern NIR nucleus. In SDSS J110851.04+065901.4, the VLBI observations did not detect any compact components, but the VLA observations allowed us to identify a possible compact core in the region of the north-western optical/NIR nucleus. In this source we find kpc-scale extended radio emission that is spatially coincident to the ultraviolet continuum and to the extended emission narrow line region. The UV continuum is significantly obscured since the amount of extended radio emission yields a star formation rate of about 110 M⊙ yr-1, which is an order of magnitude larger than implied by the observed ultraviolet emission. Our analysis confirms the presence of only one AGN in the two candidate binary AGNs. FITS files of the reduced images are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/588/A102

  15. Strain differences in arsenic-induced oxidative lesion via arsenic biomethylation between C57BL/6J and 129X1/SvJ mice

    NASA Astrophysics Data System (ADS)

    Wu, Ruirui; Wu, Xiafang; Wang, Huihui; Fang, Xin; Li, Yongfang; Gao, Lanyue; Sun, Guifan; Pi, Jingbo; Xu, Yuanyuan

    2017-03-01

    Arsenic is a common environmental and occupational toxicant with dramatic species differences in its susceptibility and metabolism. Mouse strain variability may provide a better understanding of the arsenic pathological profile but is largely unknown. Here we investigated oxidative lesion induced by acute arsenic exposure in the two frequently used mouse strains C57BL/6J and 129X1/SvJ in classical gene targeting technique. A dose of 5 mg/kg body weight arsenic led to a significant alteration of blood glutathione towards oxidized redox potential and increased hepatic malondialdehyde content in C57BL/6J mice, but not in 129X1/SvJ mice. Hepatic antioxidant enzymes were induced by arsenic in transcription in both strains and many were higher in C57BL/6J than 129X1/SvJ mice. Arsenic profiles in the liver, blood and urine and transcription of genes encoding enzymes involved in arsenic biomethylation all indicate a higher arsenic methylation capacity, which contributes to a faster hepatic arsenic excretion, in 129X1/SvJ mice than C57BL/6J mice. Taken together, C57BL/6J mice are more susceptible to oxidative hepatic injury compared with 129X1/SvJ mice after acute arsenic exposure, which is closely associated with arsenic methylation pattern of the two strains.

  16. A Murine Hypertrophic Cardiomyopathy Model: The DBA/2J Strain.

    PubMed

    Zhao, Wenyuan; Zhao, Tieqiang; Chen, Yuanjian; Zhao, Fengbo; Gu, Qingqing; Williams, Robert W; Bhattacharya, Syamal K; Lu, Lu; Sun, Yao

    2015-01-01

    Familial hypertrophic cardiomyopathy (HCM) is attributed to mutations in genes that encode for the sarcomere proteins, especially Mybpc3 and Myh7. Genotype-phenotype correlation studies show significant variability in HCM phenotypes among affected individuals with identical causal mutations. Morphological changes and clinical expression of HCM are the result of interactions with modifier genes. With the exceptions of angiotensin converting enzyme, these modifiers have not been identified. Although mouse models have been used to investigate the genetics of many complex diseases, natural murine models for HCM are still lacking. In this study we show that the DBA/2J (D2) strain of mouse has sequence variants in Mybpc3 and Myh7, relative to widely used C57BL/6J (B6) reference strain and the key features of human HCM. Four-month-old of male D2 mice exhibit hallmarks of HCM including increased heart weight and cardiomyocyte size relative to B6 mice, as well as elevated markers for cardiac hypertrophy including β-myosin heavy chain (MHC), atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and skeletal muscle alpha actin (α1-actin). Furthermore, cardiac interstitial fibrosis, another feature of HCM, is also evident in the D2 strain, and is accompanied by up-regulation of type I collagen and α-smooth muscle actin (SMA)-markers of fibrosis. Of great interest, blood pressure and cardiac function are within the normal range in the D2 strain, demonstrating that cardiac hypertrophy and fibrosis are not secondary to hypertension, myocardial infarction, or heart failure. Because D2 and B6 strains have been used to generate a large family of recombinant inbred strains, the BXD cohort, the D2 model can be effectively exploited for in-depth genetic analysis of HCM susceptibility and modifier screens.

  17. VizieR Online Data Catalog: PSR J1023+0038 & XSS J12270-4859 VRi polarimetry (Baglio+, 2016)

    NASA Astrophysics Data System (ADS)

    Baglio, M. C.; D'Avanzo, P.; Campana, S.; Coti Zelati, F.; Covino, S.; Russell, D. M.

    2016-05-01

    The systems PSR J1023+0038 and XSS J12270-4859 were observed in quiescence on 8 and 9 February 2015 (respectively) with the ESO New Technology Telescope (NTT) located at La Silla (Chile), equipped with the EFOSC2 camera in polarimetric mode, using the B, V, R, i filters. (6 data files).

  18. Joint Spacelab-J (SL-J) Activities at the Huntsville Operations Support Center (HOSC) Spacelab

    NASA Technical Reports Server (NTRS)

    1999-01-01

    The science laboratory, Spacelab-J (SL-J), flown aboard the STS-47 flight was a joint venture between NASA and the National Space Development Agency of Japan (NASDA) utilizing a manned Spacelab module. The mission conducted 24 materials science and 20 life science experiments, of which 35 were sponsored by NASDA, 7 by NASA, and two collaborative efforts. Materials science investigations covered such fields as biotechnology, electronic materials, fluid dynamics and transport phenomena, glasses and ceramics, metals and alloys, and acceleration measurements. Life sciences included experiments on human health, cell separation and biology, developmental biology, animal and human physiology and behavior, space radiation, and biological rhythms. Test subjects included the crew, Japanese koi fish (carp), cultured animal and plant cells, chicken embryos, fruit flies, fungi and plant seeds, and frogs and frog eggs. Featured together in joint ground activities during the SL-J mission are NASA/NASDA personnel at the Huntsville Operations Support Center (HOSC) Spacelab Payload Operations Control Center (SL POCC) at Marshall Space Flight Center (MSFC).

  19. jà vu experiences in patients with schizophrenia.

    PubMed

    Adachi, Takuya; Adachi, Naoto; Takekawa, Yoshikazu; Akanuma, Nozomi; Ito, Masumi; Matsubara, Ryouji; Ikeda, Hiroshi; Kimura, Michihiro; Arai, Heii

    2006-01-01

    To investigate whether déjà vu experiences are psychopathologic phenomena, we studied the frequency and characteristics of déjà vu experiences in patients with schizophrenia. One hundred thirteen patients with schizophrenia and 386 nonclinical control subjects were evaluated with the Inventory of Déjà vu Experiences Assessment. The frequency and features of déjà vu experiences were compared between the 2 groups. The patients with schizophrenia had déjà vu experiences less frequently (53.1%) than did the nonclinical subjects (76.2%). The frequency of déjà vu experiences did not correlate significantly with age at evaluation or education level among the patients with schizophrenia. Most characteristics of déjà vu experiences of the patients were comparable with those of the control subjects. However, the experiences of the patients tended to be longer and more monotonous. The patients often felt alert, oppressed, and disturbed by the experiences. They appeared to have the experiences under unpleasant mental or physical states. Their déjà vu experiences are not primarily different in nature from those of the nonclinical subjects. The decreased frequency of the experiences in the patients may suggest déjà vu experiences as nonpathologic phenomena.

  20. 26 CFR 1.415(j)-1 - Limitation year.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 5 2010-04-01 2010-04-01 false Limitation year. 1.415(j)-1 Section 1.415(j)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Pension, Profit-Sharing, Stock Bonus Plans, Etc. § 1.415(j)-1 Limitation year. (a) In...

  1. Split Active Asteroid P/2016 J1 (PANSTARRS)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hui, Man-To; Jewitt, David; Du, Xinnan, E-mail: pachacoti@ucla.edu

    We present a photometric and astrometric study of the split active asteroid P/2016 J1 (PANSTARRS). The two components (hereafter J1-A and J1-B) separated either ∼1500 days (2012 May to June) or 2300 days (2010 April) prior to the current epoch, with a separation speed V {sub sep} = 0.70 ± 0.02 m s{sup −1} for the former scenario and 0.83 ± 0.06 m s{sup −1} for the latter. Keck photometry reveals that the two fragments have similar, Sun-like colors that are comparable to the colors of primitive C- and G-type asteroids. With a nominal comet-like albedo, p{sub R} = 0.04, the effective, dust-contaminated cross sections are estimated tomore » be 2.4 km{sup 2} for J1-A and 0.5 km{sup 2} for J1-B. We estimate that the nucleus radii lie in the range 140 ≲  R {sub N} ≲ 900 m for J1-A and 40 ≲  R {sub N} ≲ 400 m for J1-B. A syndyne–synchrone simulation shows that both components have been active for 3–6 months, by ejecting dust grains at speeds ∼0.5 m s{sup −1} with rates ∼1 kg s{sup −1} for J1-A and 0.1 kg s{sup −1} for J1-B. In its present orbit, the rotational spin-up and devolatilization times of 2016 J1 are very small compared to the age of the solar system, raising the question of why this object still exists. We suggest that ice that was formerly buried within this asteroid became exposed at the surface, perhaps via a small impact, and that sublimation torques then rapidly drove it to breakup. Further disintegration events are anticipated owing to the rotational instability.« less

  2. J-PLUS: The Javalambre Photometric Local Universe Survey

    NASA Astrophysics Data System (ADS)

    Cenarro, Javier; Marin-Franch, Antonio; Moles, Mariano; Cristobal-Hornillos, David; Mendes de Oliveira, Claudia; Sodre, Laerte

    2015-08-01

    The Javalambre-Photometric Local Universe Survey, J-PLUS (www.j-plus.es), is defined to observe 8500 deg2 of the sky visible from the Javalambre Observatory (Teruel, Spain) with the panoramic camera T80Cam at the JAST/T80 telescope, using a set of 12 broad, intermediate and narrow band optical filters. The Project is particularly designed to carry out the photometric calibration of J-PAS (http://j-pas.org). For this reason, some J-PLUS filters are located at key stellar spectral features that allow to retrieve very accurate spectral energy distributions for more than 5 millions of stars in our Galaxy. Beyond the calibration goals, the unusually large FOV of T80Cam, 2deg2, together with the unique width and location of some filters, turn the J-PLUS Project into a powerful 3D view of the nearby Universe, mapping more than 20 millions of galaxies with reliable distance determinations and a similar number of stars of the Milky Way halo. At a rate of 100 gigabytes of data per night, J-PLUS will provide unprecedented multi-color images of the Universe to address a wide variety of astrophysical questions related with cosmology, large scale structure, galaxy clusters, 2D stellar populations and star formation studies in galaxies, the discovery of high redshift galaxies at specific redshift slices, quasars, supernovae, Milky Way science and structure, and minor bodies in the Solar System. In addition, the repetition of the whole area over time in certain filters will allow to face variability studies in the time domain.Complementing J-PLUS, a replica of the JAST/T80 telescope, T80Cam and the J-PLUS filters have been installed at the CTIO, allowing to extend the project to the Southern Hemisphere. J-PLUS together with the southern extension, S-PLUS, constitute an All-sky Photometric Local Universe Survey whose details and scientific applications are the bulk of the present talk.

  3. Michael J. Fox: Spurring Research on Parkinson's

    MedlinePlus

    ... on. Feature: Parkinson's Disease Michael J. Fox: Spurring Research on Parkinson's Past Issues / Winter 2014 Table of ... founded the Michael J. Fox Foundation for Parkinson's Research in the year 2000. Photo courtesy of Shutterstock " ...

  4. J-2X Test Articles Using FDM Process

    NASA Technical Reports Server (NTRS)

    Anderson, Ted; Ruf, Joe; Steele, Phil

    2010-01-01

    This viewgraph presentation gives a brief history of the J-2X engine, along with detailed description of the material demonstrator and test articles that were created using Fused Deposition Modeling (FDM) process.

  5. Near-infrared photometry of WISE J085510.74-071442.5

    NASA Astrophysics Data System (ADS)

    Zapatero Osorio, M. R.; Lodieu, N.; Béjar, V. J. S.; Martín, E. L.; Ivanov, V. D.; Bayo, A.; Boffin, H. M. J.; Mužić, K.; Minniti, D.; Beamín, J. C.

    2016-08-01

    Aims: We aim at obtaining near-infrared photometry and deriving the mass, age, temperature, and surface gravity of WISE J085510.74-071442.5 (J0855-0714), which is the coolest object beyond the solar system currently known. Methods: We used publicly available data from the archives of the Hubble Space Telescope (HST) and the Very Large Telescope (VLT) to determine the emission of this source at 1.153 μm (F110W) and 1.575 μm (CH4-off). J0855-0714 was detected at both wavelengths with a signal-to-noise ratio of ≈10 (F110W) and ≈4 (CH4-off) at the peak of the corresponding point-spread-functions. Results: This is the first detection of J0855-0714 in the H-band wavelengths. We measured 26.31 ± 0.10 and 23.22 ± 0.35 mag in F110W and CH4-off (Vega system). J0855-0714 remains unresolved in the HST images that have a spatial resolution of 0.22''. Companions at separations of 0.5 AU (similar mass and brightness) and at ~1 AU (≈1 mag fainter in the F110W filter) are discarded. By combining the new data with published photometry, including non-detections, we build the spectral energy distribution of J0855-0714 from 0.89 through 22.09 μm, and contrast it against current solar-metallicity models of planetary atmospheres. We determine that the best spectral fit yields a temperature of 225-250 K, a bolometric luminosity of log L/L⊙ = -8.57, and a high surface gravity of log g = 5.0 (cm s-2), which suggests an old age although a gravity this high is not fully compatible with evolutionary models. After comparing our data with the cooling theory for brown dwarfs and planets, we infer a mass in the interval 2-10 MJup for ages of 1-12 Gyr and high atmospheric gravities of log g ⪆ 3.5 (cm s-2). If it had the age of the Sun, J0855-0714 would be a ≈5-MJup free-floating planetary-mass object. Conclusions: J0855-0714 meets the mass values previously determined for free-floating planetary-mass objects discovered in star-forming regions and young stellar clusters. Based on

  6. STS-47 Spacelab-J Onboard Photograph

    NASA Technical Reports Server (NTRS)

    1992-01-01

    The Spacelab-J (SL-J) mission was a joint venture between NASA and the National Space Development Agency of Japan (NASDA) utilizing a marned Spacelab module. Materials science investigations covered such fields as biotechnology, electronic materials, fluid dynamics and transport phenomena, glasses and ceramics, metals and alloys, and acceleration measurements. Life sciences included experiments on human health, cell separation and biology, developmental biology, animal and human physiology and behavior, space radiation, and biological rhythms. Before long-term space ventures are attempted, numerous questions must be answered: how will gravity play in the early development of an organism, and how will new generations of a species be conceived and develop normally in microgravity. The Effects of Weightlessness on the Development of Amphibian Eggs Fertilized in Space experiment aboard SL-J examined aspects of these questions. To investigate the effect of microgravity on amphibian development, female frogs carried aboard SL-J were induced to ovulate and shed eggs. These eggs were then fertilized in the microgravity environment. Half were incubated in microgravity, while the other half were incubated in a centrifuge that spins to simulate normal gravity. This photograph shows astronaut Mark Lee working with one of the adult female frogs inside the incubator. The mission also examined the swimming behavior of tadpoles grown in the absence of gravity. The Spacelab-J was launched aboard the Space Shuttle Orbiter Endeavour on September 12, 1992.

  7. Exclusive decay of P-wave bottomonium into double J/{psi}

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang Juan; Institute of Theoretical Physics, Shanxi University, Taiyuan, Shanxi 030006; Dong Hairong

    2011-11-01

    We calculate the relativistic corrections of J/{psi}, including electromagnetic corrections, to {chi}{sub b}J{yields}J/{psi}J/{psi} in the framework of nonrelativistic QCD factorization. The relativistic effects are found to increase the lower-order prediction for the decay width by about 10%, while the electromagnetism contribution is very small, about 0.2% for {chi}{sub b0} and {chi}{sub b2}. The total branching ratios are predicted to be of order 10{sup -5} for {chi}{sub b0,b2}{yields}J/{psi}J/{psi}, but 10{sup -11} for {chi}{sub b1}{yields}J/{psi}J/{psi}, since there is only electromagnetism contribution in this channel. We predict it is possible to observe these reactions in LHC.

  8. Phylogeny-dominant classification of J-proteins in Arabidopsis thaliana and Brassica oleracea.

    PubMed

    Zhang, Bin; Qiu, Han-Lin; Qu, Dong-Hai; Ruan, Ying; Chen, Dong-Hong

    2018-04-05

    Hsp40s or DnaJ/J-proteins are evolutionarily conserved in all organisms as co-chaperones of molecular chaperone HSP70s that mainly participate in maintaining cellular protein homeostasis, such as protein folding, assembly, stabilization, and translocation under normal conditions as well as refolding and degradation under environmental stresses. It has been reported that Arabidopsis J-proteins are classified into four classes (types A-D) according to domain organization, but their phylogenetic relationships are unknown. Here, we identified 129 J-proteins in the world-wide popular vegetable Brassica oleracea, a close relative of the model plant Arabidopsis, and also revised the information of Arabidopsis J-proteins based on the latest online bioresources. According to phylogenetic analysis with domain organization and gene structure as references, the J-proteins from Arabidopsis and B. oleracea were classified into 15 main clades (I-XV) separated by a number of undefined small branches with remote relationship. Based on the number of members, they respectively belong to multigene clades, oligo-gene clades, and mono-gene clades. The J-protein genes from different clades may function together or separately to constitute a complicated regulatory network. This study provides a constructive viewpoint for J-protein classification and an informative platform for further functional dissection and resistant genes discovery related to genetic improvement of crop plants.

  9. Spectral Variability of Two Rapidly Rotating Brown Dwarfs: 2MASS J08354256-0819237 and 2MASS J18212815+1414010

    NASA Astrophysics Data System (ADS)

    Schlawin, E.; Burgasser, Adam J.; Karalidi, T.; Gizis, J. E.; Teske, J.

    2017-11-01

    L dwarfs exhibit low-level, rotationally modulated photometric variability generally associated with heterogeneous, cloud-covered atmospheres. The spectral character of these variations yields insight into the particle sizes and vertical structure of the clouds. Here, we present the results of a high-precision, ground-based, near-infrared, spectral monitoring study of two mid-type L dwarfs that have variability reported in the literature, 2MASS J08354256-0819237 and 2MASS J18212815+1414010, using the SpeX instrument on the Infrared Telescope Facility. By simultaneously observing a nearby reference star, we achieve < 0.15 % per-band sensitivity in relative brightness changes across the 0.9-2.4 μm bandwidth. We find that 2MASS J0835-0819 exhibits marginal (≲0.5% per band) variability with no clear spectral dependence, while 2MASS J1821+1414 varies by up to ±1.5% at 0.9 μm, with the variability amplitude declining toward longer wavelengths. The latter result extends the variability trend observed in prior HST/WFC3 spectral monitoring of 2MASS J1821+1414, and we show that the full 0.9-2.4 μm variability amplitude spectrum can be reproduced by Mie extinction from dust particles with a log-normal particle size distribution with a median radius of 0.24 μm. We do not detect statistically significant phase variations with wavelength. The different variability behavior of 2MASS J0835-0819 and 2MASS J1821+1414 suggests dependencies on viewing angle and/or overall cloud content, underlying factors that can be examined through a broader survey.

  10. Joint Chiefs of Staff > Directorates > J5 | Strategic Plans and Policy

    Science.gov Websites

    Quadrilateral Logistics Forum J5 | Strategic Plans and Policy J6 | C4 & Cyber J7 | Joint Force Development J8 | Force Structure, Resources & Assessment Contact J5 Strategic Plans and Policy Home : Directorates : J5 | Strategic Plans and Policy Mission The Joint Staff J5 proposes strategies, plans, and

  11. Swift Follow up observation of the transient source Fermi J1654-1055 (PMN J1632-1052)

    NASA Astrophysics Data System (ADS)

    Ajello, M.; Kocevski, D.; Buson, S.; Buehler, R.; Giomi, M.

    2016-02-01

    On February 25, 2016, Swift carried out a 2ks target of opportunity observation of the transient Fermi J1654-1055 (see ATel #8721). Only one source is clearly detected, within the LAT error circle, by the Swift X-ray telescope (XRT) at RA, Dec= 16h 32m 49.9s, -10d 52' 30.1" (J2000) with a 90 % uncertainty radius of 6.3 arcsec.

  12. 28 CFR 0.29j - Law enforcement authority.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Law enforcement authority. 0.29j Section 0.29j Judicial Administration DEPARTMENT OF JUSTICE ORGANIZATION OF THE DEPARTMENT OF JUSTICE 4-Office of the Inspector General § 0.29j Law enforcement authority. Subject to guidelines promulgated by the Attorney General, Special Agents of the Offic...

  13. Staff - Kurt J. Johnson | Alaska Division of Geological & Geophysical

    Science.gov Websites

    Facebook DGGS News Natural Resources Geological & Geophysical Surveys Staff - Kurt J. Johnson main content Kurt J. Johnson Kurt J. Johnson Position: Geologist, Geologic Materials Center Address: 3651

  14. Photoproduction of {J}/{ψ} mesons at HERA

    NASA Astrophysics Data System (ADS)

    Ahmed, T.; Aid, S.; Andreev, V.; Andrieu, B.; Appuhn, R.-D.; Arpagaus, M.; Babaev, A.; Baehr, J.; Bán, J.; Baranov, P.; Barrelet, E.; Bartel, W.; Barth, M.; Bassler, U.; Beck, H. P.; Behrend, H.-J.; Belousov, A.; Berger, Ch.; Bergstein, H.; Bernardi, G.; Bernet, R.; Bertrand-Coremans, G.; Besançon, M.; Beyer, R.; Biddulph, P.; Bizot, J. C.; Blodel, V.; Borras, K.; Botterweck, F.; Borrdry, V.; Braemer, A.; Brasse, F.; Braunschweig, W.; Brisson, V.; Bruncko, D.; Brune, C.; Buchholz, R.; Büngener, L.; Bürger, J.; Büsser, F. W.; Buniatian, A.; Burke, S.; Buschhorn, G.; Campbell, A. J.; Carli, T.; Charles, F.; Clarke, D.; Clegg, A. B.; Colombo, M.; Contreras, J. G.; Coughlan, J. A.; Courau, A.; Coutures, Ch.; Cozzika, G.; Criegee, L.; Cussans, D. G.; Cvach, J.; Dagoret, S.; Dainton, J. B.; Danilov, M.; Dau, W. D.; Daum, K.; David, M.; Deffur, E.; Delcourt, B.; Del Buono, L.; De Roeck, A.; De Wolf, E. A.; Di Nezza, P.; Dollfus, C.; Dowell, J. D.; Dreis, H. B.; Duboc, J.; Düllmann, D.; Dünger, O.; Duhm, H.; Ebert, J.; Ebert, T. R.; Eckerlin, G.; Efremenko, V.; Egli, S.; Ehrlichmann, H.; Eichenberger, S.; Eichler, R.; Eisele, F.; Eisenhandler, E.; Ellison, R. J.; Elsen, E.; Erdmann, M.; Erdmann, W.; Evrard, E.; Favart, L.; Fedotov, A.; Feeken, D.; Felst, R.; Feltesse, J.; Ferencei, J.; Ferrarotto, F.; Flamm, K.; Fleischer, M.; Flieser, M.; Flügge, G.; Fomenko, A.; Fominykh, B.; Forbush, M.; Formánek, J.; Foster, J. M.; Franke, G.; Fretwurst, E.; Gabathuler, E.; Gabathuler, K.; Gamerdinger, K.; Garvey, J.; Gayler, J.; Gebauer, M.; Gellrich, A.; Genzel, H.; Gerhards, R.; Goerlach, U.; Goerlich, L.; Gogitidze, N.; Goldberg, M.; Goldner, D.; Gonzalez-Pineiro, B.; Goodall, A. M.; Gorelov, I.; Goritchev, P.; Grab, C.; Grässler, H.; Grässler, R.; Greenshaw, T.; Grindhammer, G.; Gruber, A.; Grubber, C.; Haack, J.; Haidt, D.; Hajduk, L.; Hamon, O.; Hampel, M.; Hanlon, E. M.; Hapke, M.; Haynes, W. J.; Heatherington, J.; Hedberg, V.; Heinzelmann, G.; Henderson, R. C. W.; Henschel, H.; Herma, R.; Herynek, I.; Hess, M. F.; Hildesheim, W.; Hill, P.; Hiller, K. H.; Hilton, C. D.; Hladký, J.; Hoeger, K. C.; Höppner, M.; Horisberger, R.; Huet, Ph.; Hufnagel, H.; Ibbotson, M.; Itterbeck, H.; Jabiol, M.-A.; Jacholkowska, A.; Jacobsson, C.; Jaffre, M.; Janoth, J.; Jansen, T.; Jönsson, L.; Johannsen, K.; Johnson, D. P.; Johnson, L.; Jung, H.; Kalmus, P. I. P.; Kant, D.; Kaschowitz, R.; Kasselmann, P.; Kathage, U.; Kaufmann, H. H.; Kazarian, S.; Kenyon, I. R.; Kermiche, S.; Keuker, C.; Kiesling, C.; Klein, M.; Kleinwort, C.; Knies, G.; Ko, W.; Köhler, T.; Kolanoski, H.; Kole, F.; Kolya, S. D.; Korbel, V.; Korn, M.; Kostka, P.; Kotelnikov, S. K.; Krasny, M. W.; Krehbiel, H.; Krücker, D.; Krüger, U.; Krüner-Marquis, U.; Kubenka, J. P.; Küster, H.; Kurlen, T.; Kurča, T.; Kurzhöfer, J.; Kuznik, B.; Lacour, D.; Lamarche, F.; Lander, R.; Landon, M. P. J.; Lange, W.; Lanius, P.; Laporte, J.-F.; Lebedev, A.; Leverenz, C.; Levonian, S.; Ley, Ch.; Lindner, A.; Lindström, G.; Linsel, F.; Lipinski, J.; List, B.; Loch, P.; Lohmander, H.; Lopez, G. C.; Lüke, D.; Magnussen, N.; Malinovski, E.; Mani, S.; Maraček, R.; Marage, P.; Marks, J.; Marshall, R.; Martens, J.; Martin, R.; Martyn, H.-U.; Martyniak, J.; Masson, S.; Mavroidis, T.; Maxfield, S. J.; McMahon, S. J.; Mehta, A.; Meier, K.; Mercer, D.; Merz, T.; Meyer, C. A.; Meyer, H.; Meyer, J.; Mikocki, S.; Milstead, D.; Moreau, F.; Morris, J. V.; Müller, G.; Müller, K.; Murín, P.; Nahnhauer, R.; Naroska, B.; Naumann, Th.; Newman, P. R.; Newton, D.; Neyret, D.; Nguyen, H. K.; Niebergall, F.; Niebuhr, C.; Nisius, R.; Nowak, G.; Noyes, G. W.; Nyberg-Werther, M.; Oberlack, H.; Obrock, U.; Olsson, J. E.; Panaro, E.; Panitch, A.; Pascaud, C.; Patel, G. D.; Peppel, E.; Perez, E.; Phillips, J. P.; Pichler, Ch.; Pitzl, D.; Pope, G.; Prell, S.; Prosi, R.; Rädel, G.; Raupach, F.; Reimer, P.; Reinshagen, S.; Ribarics, P.; Riech, V.; Riedlberger, J.; Riess, S.; Rietz, M.; Robertson, S. M.; Robmann, R.; Roloff, H. E.; Roosen, R.; Rosenbauer, K.; Rostovtsev, A.; Rouse, F.; Royon, C.; Rüter, K.; Rusakov, S.; Rybicki, K.; Rylko, R.; Sahlmann, N.; Sanchez, E.; Sankey, D. P. C.; Savitsky, M.; Schacht, P.; Schiek, S.; Schleper, P.; von Schlippe, W.; Schmidt, C.; Schmidt, D.; Schmidt, G.; Schöning, A.; Schröder, V.; Schuhmann, E.; Schwab, B.; Schwind, A.; Seehausen, U.; Sefkow, F.; Seidel, M.; Sell, R.; Semenov, A.; Shekelyan, V.; Sheviakov, I.; Shooshtari, H.; Shtarkov, L. N.; Siegmon, G.; Siewert, U.; Sirois, Y.; Skillicorn, I. O.; Smirnov, P.; Smith, J. R.; Soloviev, Y.; Spitzer, H.; Starosta, R.; Steenbock, M.; Steffen, P.; Steinberg, R.; Stella, B.; Stephens, K.; Stier, J.; Stiewe, J.; Stösslein, U.; Strachota, J.; Straumann, U.; Struczinski, W.; Sutton, J. P.; Tapprogge, S.; Taylor, R. E.; Tchernyshov, V.; Thiebaux, C.; Thompson, G.; Tichomirov, I.; Truöl, P.; Turnau, J.; Tutas, J.; Uelkes, P.; Usik, A.; Valkár, S.; Valkárová, A.; Vallée, C.; Van Esch, P.; Van Mechelen, P.; Vartapetian, A.; Vazdik, Y.; Vecko, M.; Verrecchia, P.; Villet, G.; Wacker, K.; Wagener, A.; Wagener, M.; Walker, I. W.; Walther, A.; Weber, G.; Weber, M.; Wegener, D.; Wegner, A.; Wellisch, H. P.; West, L. R.; Willard, S.; Winde, M.; Winter, G.-G.; Wright, A. E.; Wünsch, E.; Wulff, N.; Yiou, T. P.; Žáček, J.; Zarbock, D.; Zhang, Z.; Zimmer, M.; Zimmermann, W.; Zomer, F.; Zuber, K.; H1 Collaboration

    1994-11-01

    We present a study of {J}/{ψ} meson production in collisions of 26.7 GeV electrons with 820 GeV protons, performed with the H1-detector at the HERA collider at DESY. The {J}/{ψ} mesons are detected via their leptonic decays both to electrons and muons. Requiring exactly two particles in the detector, a cross section of σ(ep → {J}/{ψ}X) = (8.8±2.0±2.2) nb is determined for 30 GeV ≤ Wγp ≤ 180 GeV and Q2 ≲ 4 GeV 2. Using the flux of quasi-real photons with Q2 ≲ 4 GeV 2, a total production cross section of σ( γp → J/ ψX) = (56±13±14) nb is derived at an average Wγp=90 GeV. The distribution of the squared momentum transfer t from the proton to the {J}/{ψ} can be fitted using an exponential exp(- b∥ t∥) below a ∥ t∥ of 0.75 GeV 2 yielding a slope parameter of b = (4.7±1.9) GeV -2.

  15. New constraints on the TeV SNR shells RX J1713.7-3946 and HESS J1731-347

    NASA Astrophysics Data System (ADS)

    Puehlhofer, G.; Eger, P.; Doroshenko, V.; Cui, Y.; H. E. S. S. Collaboration

    2016-06-01

    Resolved TeV-emitting supernova remnants remain a small and precious class of sources to study cosmic ray acceleration in SNRs. We present new multi-wavelength results of the two prominent objects RX J1713.7-3946 and HESS J1731-347. For RX J1713.7-3946, extensive new H.E.S.S. data have permitted to study the nature of the TeV-emitting CR particles through improved broadband spectral studies, as well as through detailed investigations of morphological differences between TeV gamma-rays and X-rays. Concerning HESS J1731-347, the TeV morphology of the object and its surroundings has been studied using cosmic ray acceleration simulations of the object. The SNR also hosts a luminous X-ray emitting central compact object (CCO). Investigations of the CCO in X-rays and in the infrared have permitted to set interesting constraints on the SNR and its progenitor.

  16. Recent results of {chi}{sub cJ} decays from BESIII

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yan Liang

    2011-05-23

    Using (106{+-}4)x10{sup 6} {psi}{sup '} events collected with BESIII/BEPCII in March and April 2009, some {chi}{sub cJ} decay modes are studied, such as {chi}{sub cJ}{yields}{pi}{sup 0}{pi}{sup 0}, {chi}{sub cJ}{yields}{eta}{eta}, {chi}{sub cJ}{yields}VV, {chi}{sub cJ}{yields}{gamma}V, and so on. The precisions of these branching fraction measurements are improved, which is helpful to understand {chi}{sub cJ} decay mechanism.

  17. Stable J-aggregation enabled dual photoacoustic and fluorescence nanoparticles for intraoperative cancer imaging

    NASA Astrophysics Data System (ADS)

    Shakiba, Mojdeh; Ng, Kenneth K.; Huynh, Elizabeth; Chan, Harley; Charron, Danielle M.; Chen, Juan; Muhanna, Nidal; Foster, F. Stuart; Wilson, Brian C.; Zheng, Gang

    2016-06-01

    J-aggregates display nanoscale optical properties which enable their use in fluorescence and photoacoustic imaging applications. However, control over their optical properties in an in vivo setting is hampered by the conformational lability of the J-aggregate structure in complex biological environments. J-aggregating nanoparticles (JNP) formed by self-assembly of bacteriopheophorbide-lipid (Bchl-lipid) in lipid nanovesicles represents a novel strategy to stabilize J-aggregates for in vivo bioimaging applications. We find that 15 mol% Bchl-lipid embedded within a saturated phospholipid bilayer vesicle was optimal in terms of maximizing Bchl-lipid dye loading, while maintaining a spherical nanoparticle morphology and retaining spectral properties characteristic of J-aggregates. The addition of cholesterol maintains the stability of the J-aggregate absorption band for up to 6 hours in the presence of 90% FBS. In a proof-of-concept experiment, we successfully applied JNPs as a fluorescence contrast agent for real-time intraoperative detection of metastatic lymph nodes in a rabbit head-and-neck cancer model. Lymph node metastasis delineation was further verified by visualizing the JNP within the excised lymph node using photoacoustic imaging. Using JNPs, we demonstrate the possibility of using J-aggregates as fluorescence and photoacoustic contrast agents and may potentially spur the development of other nanomaterials that can stably induce J-aggregation for in vivo cancer bioimaging applications.J-aggregates display nanoscale optical properties which enable their use in fluorescence and photoacoustic imaging applications. However, control over their optical properties in an in vivo setting is hampered by the conformational lability of the J-aggregate structure in complex biological environments. J-aggregating nanoparticles (JNP) formed by self-assembly of bacteriopheophorbide-lipid (Bchl-lipid) in lipid nanovesicles represents a novel strategy to stabilize J

  18. Unusual Nonemissive Behavior of Rubrene J-Aggregates: A Rare Violation.

    PubMed

    Aggarwal, Nikhil; Patnaik, Archita

    2017-04-13

    Structure-property correlations in rubrene (RB) colloidal J-aggregates were unravelled by steady state and time-resolved spectroscopy in conjunction with excited state density functional calculations. The RB J-aggregate with a slippage angle θ = 30.4°, estimated from the monomeric transition dipole moment directions, exhibited a broad fwhm of 1073 cm -1 and a 5 nm red-shifted absorption band carrying a transition dipole moment (M⃗ λ agg = 1.80 D) almost equivalent to the monomeric dye (M⃗ λ mon = 1.89 D). A significantly low magnitude of exciton coupling energy, ΔE exc = -358 cm -1 for the rhombic-RB colloidal J-aggregates resulted owing to the weaker electronic communication between the largely separated RB subunits (r = 7.2 Å) and a restricted exciton delocalization over the RB J-dimer (N = 2). The RB J-dimer exhibited a perfect balance between the computed singlet (2.53 eV) and the triplet (1.29 eV) exciton energies for singlet fission (SF). Supporting this, the PL decay profile of the J-aggregates revealed a delayed fluorescence, substantiating triplet pair formation via SF. The experimental evidence for the long-lived triplet formation was furthermore confirmed by its transient absorption (T 1 → T N ) at 530 nm. Consequently, a high probability for SF and a low probability for triplet-triplet recombination, leading to a dramatic lowering in photoluminescence quantum yield from 0.172 down to 0.035 was noted. The electronic structure calculations for the RB J-dimer followed TD-DFT-M062X/6-31G+(d,p) level of theory following integral equation formalism polarizable continuum model (IEFPCM) in water. S 1 excited state for RB J-dimer was carefully analyzed using integral overlap of electron and hole density distribution (ϕ) and the defined t-indexes along all three spatial directions, and was found to be of locally excited in character.

  19. J-adaptive estimation with estimated noise statistics

    NASA Technical Reports Server (NTRS)

    Jazwinski, A. H.; Hipkins, C.

    1973-01-01

    The J-adaptive sequential estimator is extended to include simultaneous estimation of the noise statistics in a model for system dynamics. This extension completely automates the estimator, eliminating the requirement of an analyst in the loop. Simulations in satellite orbit determination demonstrate the efficacy of the sequential estimation algorithm.

  20. X-Ray Wind Tomography of IGR J17252-3616

    NASA Astrophysics Data System (ADS)

    Manousakis, Antonios; Walter, Roland

    2010-07-01

    IGR J17252-3616, a highly absorbed High Mass X-ray Binary (HMXB) with Hydrogen column density NH~(2-4)×1023 cm-2, has been observed with XMM-Newton for about one month. Observations were scheduled in order to cover the orbital-phase space as much as possible. IGR J17252-3616 shows a varying column density NH and Fe Kα line when fit with simple phenomenological models. A refined orbital solution can be derived. Spectral timing analysis allows derivation of the wind properties of the massive star.

  1. Diffractive J/Psi Production; Produção Difrativa de $J/psi$ no Experimento DØ (in Portuguese)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    dos Santos Assis Jesus, Ana Carolina

    This work presents measurements of two diffractive production ratio for heavy flavour physics with the use of a reconstructed J/Ψ → μ +μ - sample in pmore » $$\\bar{p}$$ collisions at √s = 1.96 TeV using the D0 detector at Fermilab Tevatron. These events were selected using the Luminosity Monitor detectors, the calorimeter system and the muon system in a pseudo-rapidity region with range 2.7 ≤ |η| ≤ 4.4. The measured ratio were estimated to be N$$J/Ψ\\atop{diff}$$/N$$J/Ψ\\atop{total}$$ = (1.74 ± 0.16(stat) {+-} 0.13(syst))% e N$$b\\atop{diff}$$/N$$b\\atop{total}$$ = (0.79 ± 0.11(stat) ± 0.23(syst))%.« less

  2. Chronic Intermittent Ethanol Inhalation Increases Ethanol Self-administration in both C57BL/6J and DBA/2J Mice

    PubMed Central

    McCool, Brian A.; Chappell, Ann M.

    2015-01-01

    Inbred mouse strains provide significant opportunities to understand the genetic mechanisms controlling ethanol-directed behaviors and neurobiology. They have been specifically employed to understand cellular mechanisms contributing to ethanol consumption, acute intoxication, and sensitivities to chronic effects. However, limited ethanol consumption by some strains has restricted our understanding of clinically relevant endpoints such as dependence-related ethanol intake. Previous work with a novel tastant-substitution procedure using monosodium glutamate (MSG or umami flavor) has shown that the procedure greatly enhances ethanol consumption by mouse strains that express limited drinking phenotypes using other methods. In the current study, we employ this MSG-substitution procedure to examine how ethanol dependence, induced with passive vapor inhalation, modifies ethanol drinking in C57BL/6J and DBA/2J mice. These strains represent ‘high’ and ‘low’ drinking phenotypes, respectively. We found that the MSG substitution greatly facilitates ethanol drinking in both strains, and likewise, ethanol dependence increased ethanol consumption regardless of strain. However, DBA/2J mice exhibited greater sensitivity dependence-enhanced drinking, as represented by consumption behaviors directed at lower ethanol concentrations and relative to baseline intake levels. DBA/2J mice also exhibited significant withdrawal-associated anxiety-like behavior while C57BL/6J mice did not. These findings suggest that the MSG-substitution procedure can be employed to examine dependence-enhanced ethanol consumption across a range of drinking phenotypes, and that C57BL/6J and DBA/2J mice may represent unique neurobehavioral pathways for developing dependence-enhanced ethanol consumption. PMID:25659650

  3. Chronic intermittent ethanol inhalation increases ethanol self-administration in both C57BL/6J and DBA/2J mice.

    PubMed

    McCool, Brian A; Chappell, Ann M

    2015-03-01

    Inbred mouse strains provide significant opportunities to understand the genetic mechanisms controlling ethanol-directed behaviors and neurobiology. They have been specifically employed to understand cellular mechanisms contributing to ethanol consumption, acute intoxication, and sensitivities to chronic effects. However, limited ethanol consumption by some strains has restricted our understanding of clinically relevant endpoints such as dependence-related ethanol intake. Previous work with a novel tastant-substitution procedure using monosodium glutamate (MSG or umami flavor) has shown that the procedure greatly enhances ethanol consumption by mouse strains that express limited drinking phenotypes using other methods. In the current study, we employ this MSG-substitution procedure to examine how ethanol dependence, induced with passive vapor inhalation, modifies ethanol drinking in C57BL/6J and DBA/2J mice. These strains represent 'high' and 'low' drinking phenotypes, respectively. We found that the MSG substitution greatly facilitates ethanol drinking in both strains, and likewise, ethanol dependence increased ethanol consumption regardless of strain. However, DBA/2J mice exhibited greater sensitivity dependence-enhanced drinking, as represented by consumption behaviors directed at lower ethanol concentrations and relative to baseline intake levels. DBA/2J mice also exhibited significant withdrawal-associated anxiety-like behavior while C57BL/6J mice did not. These findings suggest that the MSG-substitution procedure can be employed to examine dependence-enhanced ethanol consumption across a range of drinking phenotypes, and that C57BL/6J and DBA/2J mice may represent unique neurobehavioral pathways for developing dependence-enhanced ethanol consumption. Copyright © 2015 Elsevier Inc. All rights reserved.

  4. What is French for déjà vu? Descriptions of déjà vu in native French and English speakers.

    PubMed

    Fortier, Jonathan; Moulin, Chris J A

    2015-11-01

    Little is known about how people characterise and classify the experience of déjà vu. The term déjà vu might capture a range of different phenomena and people may use it differently. We examined the description of déjà vu in two languages: French and English, hypothesising that the use of déjà vu would vary between the two languages. In French, the phrase déjà vu can be used to indicate a veridical experience of recognition - as in "I have already seen this face before". However, the same is not true in English. In an online questionnaire, we found equal rates of déjà vu amongst French and English speakers, and key differences in how the experience was described. As expected, the French group described the experience as being more frequent, but there was the unexpected finding that they found it to be more troubling. Copyright © 2015 Elsevier Inc. All rights reserved.

  5. Study of B+/ --> J/psi pi+/- and B+/ -->J/psi K+/- decays: measurement of the ratio of branching fractions and search for direct CP violation.

    PubMed

    Aubert, B; Barate, R; Boutigny, D; Couderc, F; Gaillard, J-M; Hicheur, A; Karyotakis, Y; Lees, J P; Tisserand, V; Zghiche, A; Palano, A; Pompili, A; Chen, J C; Qi, N D; Rong, G; Wang, P; Zhu, Y S; Eigen, G; Ofte, I; Stugu, B; Abrams, G S; Borgland, A W; Breon, A B; Brown, D N; Button-Shafer, J; Cahn, R N; Charles, E; Day, C T; Gill, M S; Gritsan, A V; Groysman, Y; Jacobsen, R G; Kadel, R W; Kadyk, J; Kerth, L T; Kolomensky, Yu G; Kukartsev, G; LeClerc, C; Levi, M E; Lynch, G; Mir, L M; Oddone, P J; Orimoto, T J; Pripstein, M; Roe, N A; Ronan, M T; Shelkov, V G; Telnov, A V; Wenzel, W A; Ford, K; Harrison, T J; Hawkes, C M; Morgan, S E; Watson, A T; Watson, N K; Fritsch, M; Goetzen, K; Held, T; Koch, H; Lewandowski, B; Pelizaeus, M; Steinke, M; Boyd, J T; Chevalier, N; Cottingham, W N; Kelly, M P; Latham, T E; Wilson, F F; Abe, K; Cuhadar-Donszelmann, T; Hearty, C; Mattison, T S; McKenna, J A; Thiessen, D; Kyberd, P; Teodorescu, L; Blinov, V E; Bukin, A D; Druzhinin, V P; Golubev, V B; Ivanchenko, V N; Kravchenko, E A; Onuchin, A P; Serednyakov, S I; Skovpen, Yu I; Solodov, E P; Yushkov, A N; Best, D; Bruinsma, M; Chao, M; Eschrich, I; Kirkby, D; Lankford, A J; Mandelkern, M; Mommsen, R K; Roethel, W; Stoker, D P; Buchanan, C; Hartfiel, B L; Gary, J W; Shen, B C; Wang, K; del Re, D; Hadavand, H K; Hill, E J; MacFarlane, D B; Paar, H P; Rahatlou, Sh; Sharma, V; Berryhill, J W; Campagnari, C; Dahmes, B; Levy, S L; Long, O; Lu, A; Mazur, M A; Richman, J D; Verkerke, W; Beck, T W; Eisner, A M; Heusch, C A; Lockman, W S; Schalk, T; Schmitz, R E; Schumm, B A; Seiden, A; Spradlin, P; Williams, D C; Wilson, M G; Albert, J; Chen, E; Dubois-Felsmann, G P; Dvoretskii, A; Hitlin, D G; Narsky, I; Piatenko, T; Porter, F C; Ryd, A; Samuel, A; Yang, S; Jayatilleke, S; Mancinelli, G; Meadows, B T; Sokoloff, M D; Abe, T; Blanc, F; Bloom, P; Chen, S; Clark, P J; Ford, W T; Nauenberg, U; Olivas, A; Rankin, P; Smith, J G; van Hoek, W C; Zhang, L; Harton, J L; Hu, T; Soffer, A; Toki, W H; Wilson, R J; Altenburg, D; Brandt, T; Brose, J; Colberg, T; Dickopp, M; Feltresi, E; Hauke, A; Lacker, H M; Maly, E; Müller-Pfefferkorn, R; Nogowski, R; Otto, S; Schubert, J; Schubert, K R; Schwierz, R; Spaan, B; Bernard, D; Bonneaud, G R; Brochard, F; Grenier, P; Thiebaux, Ch; Vasileiadis, G; Verderi, M; Bard, D J; Khan, A; Lavin, D; Muheim, F; Playfer, S; Andreotti, M; Azzolini, V; Bettoni, D; Bozzi, C; Calabrese, R; Cibinetto, G; Luppi, E; Negrini, M; Sarti, A; Treadwell, E; Baldini-Ferroli, R; Calcaterra, A; de Sangro, R; Finocchiaro, G; Patteri, P; Piccolo, M; Zallo, A; Buzzo, A; Capra, R; Contri, R; Crosetti, G; Lo Vetere, M; Macri, M; Monge, M R; Passaggio, S; Patrignani, C; Robutti, E; Santroni, A; Tosi, S; Bailey, S; Brandenburg, G; Morii, M; Won, E; Dubitzky, R S; Langenegger, U; Bhimji, W; Bowerman, D A; Dauncey, P D; Egede, U; Gaillard, J R; Morton, G W; Nash, J A; Taylor, G P; Grenier, G J; Lee, S-J; Mallik, U; Cochran, J; Crawley, H B; Lamsa, J; Meyer, W T; Prell, S; Rosenberg, E I; Yi, J; Davier, M; Grosdidier, G; Höcker, A; Laplace, S; Le Diberder, F; Lepeltier, V; Lutz, A M; Petersen, T C; Plaszczynski, S; Schune, M H; Tantot, L; Wormser, G; Cheng, C H; Lange, D J; Simani, M C; Wright, D M; Bevan, A J; Coleman, J P; Fry, J R; Gabathuler, E; Gamet, R; Kay, M; Parry, R J; Payne, D J; Sloane, R J; Touramanis, C; Back, J J; Harrison, P F; Mohanty, G B; Brown, C L; Cowan, G; Flack, R L; Flaecher, H U; George, S; Green, M G; Kurup, A; Marker, C E; McMahon, T R; Ricciardi, S; Salvatore, F; Vaitsas, G; Winter, M A; Brown, D; Davis, C L; Allison, J; Barlow, N R; Barlow, R J; Hart, P A; Hodgkinson, M C; Lafferty, G D; Lyon, A J; Williams, J C; Farbin, A; Hulsbergen, W D; Jawahery, A; Kovalskyi, D; Lae, C K; Lillard, V; Roberts, D A; Blaylock, G; Dallapiccola, C; Flood, K T; Hertzbach, S S; Kofler, R; Koptchev, V B; Moore, T B; Saremi, S; Staengle, H; Willocq, S; Cowan, R; Sciolla, G; Taylor, F; Yamamoto, R K; Mangeol, D J J; Patel, P M; Robertson, S H; Lazzaro, A; Palombo, F; Bauer, J M; Cremaldi, L; Eschenburg, V; Godang, R; Kroeger, R; Reidy, J; Sanders, D A; Summers, D J; Zhao, H W; Brunet, S; Côté, D; Taras, P; Nicholson, H; Cartaro, C; Cavallo, N; Fabozzi, F; Gatto, C; Lista, L; Monorchio, D; Paolucci, P; Piccolo, D; Sciacca, C; Baak, M; Raven, G; Wilden, L; Jessop, C P; LoSecco, J M; Gabriel, T A; Allmendinger, T; Brau, B; Gan, K K; Honscheid, K; Hufnagel, D; Kagan, H; Kass, R; Pulliam, T; Ter-Antonyan, R; Wong, Q K; Brau, J; Frey, R; Igonkina, O; Potter, C T; Sinev, N B; Strom, D; Torrence, E; Colecchia, F; Dorigo, A; Galeazzi, F; Margoni, M; Morandin, M; Posocco, M; Rotondo, M; Simonetto, F; Stroili, R; Tiozzo, G; Voci, C; Benayoun, M; Briand, H; Chauveau, J; David, P; de laVassière, Ch; Del Buono, L; Hamon, O; John, M J J; Leruste, Ph; Ocariz, J; Pivk, M; Roos, L; T'Jampens, S; Therin, G; Manfredi, P F; Re, V; Behera, P K; Gladney, L; Guo, Q H; Panetta, J; Anulli, F; Biasini, M; Peruzzi, I M; Pioppi, M; Angelini, C; Batignani, G; Bettarini, S; Bondioli, M; Bucci, F; Calderini, G; Carpinelli, M; Del Gamba, V; Forti, F; Giorgi, M A; Lusiani, A; Marchiori, G; Martinez-Vidal, F; Morganti, M; Neri, N; Paoloni, E; Rama, M; Rizzo, G; Sandrelli, F; Walsh, J; Haire, M; Judd, D; Paick, K; Wagoner, D E; Danielson, N; Elmer, P; Lu, C; Miftakov, V; Olsen, J; Smith, A J S; Varnes, E W; Bellini, F; Cavoto, G; Faccini, R; Ferrarotto, F; Ferroni, F; Gaspero, M; Li Gioi, L; Mazzoni, M A; Morganti, S; Pierini, M; Piredda, G; Safai Tehrani, F; Voena, C; Christ, S; Wagner, G; Waldi, R; Adye, T; De Groot, N; Franek, B; Geddes, N I; Gopal, G P; Olaiya, E O; Xella, S M; Aleksan, R; Emery, S; Gaidot, A; Ganzhur, S F; Giraud, P-F; Hamel de Monchenault, G; Kozanecki, W; Langer, M; Legendre, M; London, G W; Mayer, B; Schott, G; Vasseur, G; Yèche, Ch; Zito, M; Purohit, M V; Weidemann, A W; Yumiceva, F X; Aston, D; Bartoldus, R; Berger, N; Boyarski, A M; Buchmueller, O L; Convery, M R; Cristinziani, M; De Nardo, G; Dong, D; Dorfan, J; Dujmic, D; Dunwoodie, W; Elsen, E E; Field, R C; Glanzman, T; Gowdy, S J; Hadig, T; Halyo, V; Hryn'ova, T; Innes, W R; Kelsey, M H; Kim, P; Kocian, M L; Leith, D W G S; Libby, J; Luitz, S; Luth, V; Lynch, H L; Marsiske, H; Messner, R; Muller, D R; O'Grady, C P; Ozcan, V E; Perazzo, A; Perl, M; Petrak, S; Ratcliff, B N; Roodman, A; Salnikov, A A; Schindler, R H; Schwiening, J; Simi, G; Snyder, A; Soha, A; Stelzer, J; Su, D; Sullivan, M K; Va'vra, J; Wagner, S R; Weaver, M; Weinstein, A J R; Wisniewski, W J; Wittgen, M; Wright, D H; Young, C C; Burchat, P R; Edwards, A J; Meyer, T I; Petersen, B A; Roat, C; Ahmed, S; Alam, M S; Ernst, J A; Saeed, M A; Saleem, M; Wappler, F R; Bugg, W; Krishnamurthy, M; Spanier, S M; Eckmann, R; Kim, H; Ritchie, J L; Satpathy, A; Schwitters, R F; Izen, J M; Kitayama, I; Lou, X C; Ye, S; Bianchi, F; Bona, M; Gallo, F; Gamba, D; Borean, C; Bosisio, L; Cossutti, F; Della Ricca, G; Dittongo, S; Grancagnolo, S; Lanceri, L; Poropat, P; Vitale, L; Vuagnin, G; Panvini, R S; Banerjee, Sw; Brown, C M; Fortin, D; Jackson, P D; Kowalewski, R; Roney, J M; Band, H R; Dasu, S; Datta, M; Eichenbaum, A M; Hollar, J J; Johnson, J R; Kutter, P E; Li, H; Liu, R; Di Lodovico, F; Mihalyi, A; Mohapatra, A K; Pan, Y; Prepost, R; Sekula, S J; Tan, P; von Wimmersperg-Toeller, J H; Wu, J; Wu, S L; Yu, Z; Neal, H

    2004-06-18

    We study B+/ --> J/psi pi(+/-) and B+/ --> J/psi K+/- decays in a sample of about 89 x 10(6) BB pairs collected with the BABAR detector at the PEP-II asymmetric B factory at SLAC. We observe a signal of 244+/-20 B+/ --> J/psi pi(+/-) events and determine the ratio B(B+/ --> J/psi pi(+/-))/B(B+/ --> J/psi K+/-) to be [5.37+/-0.45(stat)+/-0.11(syst)]%. The charge asymmetries for the B+/ --> J/psi pi(+/-) and B+/ --> J/psi K+/- decays are determined to be A(pi)=0.123+/-0.085(stat)+/-0.004(syst) and A(K)=0.030+/-0.015(stat)+/-0.006(syst), respectively.

  6. Testing and Functions of the J2X Gas Generator

    NASA Technical Reports Server (NTRS)

    Miller, Nicholas

    2009-01-01

    The Ares I, NASA s new solid rocket based crew launch vehicle, is a two stage in line rocket that has made its waytothe forefront of NASA s endeavors. The Ares I s Upper Stage (US) will be propelled by a J-2X engine which is fueled by liquid hydrogen and liquid oxygen. The J-2X is a variation based on two of its predecessor s, the J-2 and J-2S engines. ET50 is providing the design support for hardware required to run tests on the J-2X Gas Generator (GG) that increases the delivery pressure of the supplied combustion fuels that the engine burns. The test area will be running a series of tests using different lengths and curved segments of pipe and different sized nozzles to determine the configuration that best satisfies the thrust, heat, and stability requirements for the engine. I have had to research the configurations that are being tested and gain an understanding of the purpose of the tests. I then had to research the parts that would be used in the test configurations. I was taken to see parts similar to the ones used in the test configurations and was allowed to review drawings and dimensions used for those parts. My job over this summer has been to use the knowledge I have gained to design, model, and create drawings for the un-fabricated parts that are necessary for the J-2X Workhorse Gas Generator Phase IIcTest.

  7. Structural insights into translational recoding by frameshift suppressor tRNASufJ

    PubMed Central

    Fagan, Crystal E.; Maehigashi, Tatsuya; Dunkle, Jack A.; Miles, Stacey J.

    2014-01-01

    The three-nucleotide mRNA reading frame is tightly regulated during translation to ensure accurate protein expression. Translation errors that lead to aberrant protein production can result from the uncoupled movement of the tRNA in either the 5′ or 3′ direction on mRNA. Here, we report the biochemical and structural characterization of +1 frameshift suppressor tRNASufJ, a tRNA known to decode four, instead of three, nucleotides. Frameshift suppressor tRNASufJ contains an insertion 5′ to its anticodon, expanding the anticodon loop from seven to eight nucleotides. Our results indicate that the expansion of the anticodon loop of either ASLSufJ or tRNASufJ does not affect its affinity for the A site of the ribosome. Structural analyses of both ASLSufJ and ASLThr bound to the Thermus thermophilus 70S ribosome demonstrate both ASLs decode in the zero frame. Although the anticodon loop residues 34–37 are superimposable with canonical seven-nucleotide ASLs, the single C31.5 insertion between nucleotides 31 and 32 in ASLSufJ imposes a conformational change of the anticodon stem, that repositions and tilts the ASL toward the back of the A site. Further modeling analyses reveal that this tilting would cause a distortion in full-length A-site tRNASufJ during tRNA selection and possibly impede gripping of the anticodon stem by 16S rRNA nucleotides in the P site. Together, these data implicate tRNA distortion as a major driver of noncanonical translation events such as frameshifting. PMID:25352689

  8. Measurements of J/JΦ Φ polarization in p +p collisions at STAR

    NASA Astrophysics Data System (ADS)

    Luo, Siwei; STAR Collaboration

    2016-03-01

    Measurements of J/JΦ Φ production cross section and polarization can help understand J/JΦ Φ production mechanism in hadron collisions and distinguish among different models. J/JΦ Φ polarization could be characterized by the λθ, λφ and λinv polarization parameters, where λθ and λφ are coefficients of positron polar and azimuthal angle distribution in the J/JΦ Φ rest frame with respect to a chosen polarization axis, while λinv is a frame-independent variable calculable from λθ and λφ. J/JΦ Φ polarization parameters λθ, λφ and λinv in both helicity and Collins-Soper frames have been extracted from the STAR 2011 data in p +p collisions at √{ s} = 500 GeV, while only λθ in the helicity frame has been extracted from the STAR 2009 data in p +p collisions at √{ s} = 200 GeV. In this talk, we will present a new analysis to study J/JΦ Φ polarization using the STAR 2012 data to extract λθ, λφ and λinv in both the helicity and Collins-Soper frames in p +p collisions at √{ s} = 200 GeV.

  9. Effect of ECG filter settings on J-waves.

    PubMed

    Nakagawa, Mikiko; Tsunemitsu, Chie; Katoh, Sayo; Kamiyama, Yukari; Sano, Nario; Ezaki, Kaori; Miyazaki, Hiroko; Teshima, Yasushi; Yufu, Kunio; Takahashi, Naohiko; Saikawa, Tetsunori

    2014-01-01

    While J-waves were observed in healthy populations, variations in their reported incidence may be partly explicable by the ECG filter setting. We obtained resting 12-lead ECG recordings in 665 consecutive patients and enrolled 112 (56 men, 56 women, mean age 59.3±16.1years) who manifested J-waves on ECGs acquired with a 150-Hz low-pass filter. We then studied the J-waves on individual ECGs to look for morphological changes when 25-, 35-, 75-, 100-, and 150Hz filters were used. The notching observed with the 150-Hz filter changed to slurring (42%) or was eliminated (28%) with the 25-Hz filter. Similarly, the slurring seen with the 150-Hz filter was eliminated on 71% of ECGs recorded with the 25-Hz filter. The amplitude of J-waves was significantly lower with 25- and 35-Hz than 75-, 100-, and 150-Hz filters (p<0.0001). The ECG filter setting significantly affects the J-wave morphology. © 2013.

  10. Spectroscopy of PSN J19583553+0236163

    NASA Astrophysics Data System (ADS)

    Leonard, D. C.; Moustakas, J.; Swift, B. J.; McCarthy, D.; Bailey, V.; Carrico, E.; Carter, A.; Chui, E.; Douglas, E.; Eggeman, E.; Goldberg, R.; Grant, R.; Hartman, K.; Hellerstein, J.; Hooper, E.; Horlick-Cruz, C.; Hunter, L.; Jiles, T.; Johnson, E. D.; Kumar, K.; Lappe, L.; Lee, J.; Lee, W.; Marsh, F.; Mehta, G.; Miller, P.; Rampalli, R.; Reed, J.; Rice, K.; Saldivar, H.; Salgado-Flores, M.; Schlingman, A.; Schlingman, W. F.; Schlingman, W. M.; Scibelli, S.; Sinclair, K.; Steincamp, I.; Stock, N.; Todd, N.; Vargas, L. L. Aizpuru; Yamanaka, S.; Zachary, E.

    2011-06-01

    As part of the 2011 Advanced Teen Astronomy Camp (http://www.astronomycamp.org), we obtained a low dispersion optical spectrum (range 370-690 nm) of PSN J19583553+0236163 in UGC 11501 with the 2.3m Bok telescope (+ Boller & Chivens spectrograph) at Steward Observatory, on 2011 June 23 UT. Cross-correlation with a library of supernova spectra using the Supernova Identification code (SNID; Blondin and Tonry 2007, Ap.J.

  11. Two-peak structure in the K-edge RIXS spectra of a spatially frustrated Heisenberg antiferromagnet

    NASA Astrophysics Data System (ADS)

    Datta, Trinanjan; Luo, Cheng; Yao, Dao-Xin

    2014-03-01

    Quantum fluctuations due to spatial anisotropy and strong magnetic frustration lead to the formation of a two-peak structure in the K-edge bimagnon RIXS intensity spectra of a Jx-Jy-J2 Heisenberg model on a square lattice. We compute the RIXS intensity, including up to first order 1/S spin wave expansion correction, using the Bethe-Salpeter equation within the ladder approximation scheme. The two-peak feature occurs in both the antiferromagnetic phase and the collinear antiferromagnetic phase. A knowledge of the peak splitting energy from both magnetically ordered regime can provide experimentalists with an alternative means to measure and study the effects of local microscopic exchange constants. Cottrell Research Corporation, NSFC-11074310, NSFC-11275279, Specialized Research Fund for the Doctoral Program of Higher Education.

  12. FibrilJ: ImageJ plugin for fibrils' diameter and persistence length determination

    NASA Astrophysics Data System (ADS)

    Sokolov, P. A.; Belousov, M. V.; Bondarev, S. A.; Zhouravleva, G. A.; Kasyanenko, N. A.

    2017-05-01

    Application of microscopy to evaluate the morphology and size of filamentous proteins and amyloids requires new and creative approaches to simplify and automate the image processing. The estimation of mean values of fibrils diameter, length and bending stiffness on micrographs is a major challenge. For this purpose we developed an open-source FibrilJ plugin for the ImageJ/FiJi program. It automatically recognizes the fibrils on the surface of a mica, silicon, gold or formvar film and further analyzes them to calculate the distribution of fibrils by diameters, lengths and persistence lengths. The plugin has been validated by the processing of TEM images of fibrils formed by Sup35NM yeast protein and artificially created images of rod-shape objects with predefined parameters. Novel data obtained by SEM for Sup35NM protein fibrils immobilized on silicon and gold substrates are also presented and analyzed.

  13. Quantitative volumetric analysis of a retinoic acid induced hypoplastic model of chick thymus, using Image-J.

    PubMed

    Haque, Ayesha; Khan, Muhammad Yunus

    2017-09-01

    To assess the total volume change in a retinoic acid-induced, hypoplastic model of a chick thymus using Image-J. This experimental study was carried out at the anatomy department of College of Physicians and Surgeons, Islamabad, Pakistan, from February 2009 to February 2010, and comprised fertilised chicken eggs. The eggs were divided into experimental group A and control group C. Group A was injected with 0.3µg of retinoic acid via yolk sac to induce a defective model of a thymus with hypoplasia. The chicks were sacrificed on embryonic day 15 and at hatching. The thymus of each animal was processed, serially sectioned and stained. The total area of each section of thymus was calculated using Image-J. This total area was summed and multiplied with the thickness of each section to obtain volume. Of the 120 eggs, there were 60(50%) in each group. Image analysis revealed a highly significant decrease in the volume of the chick thymus in the experimental group A than its matched control at the time of hatching (p=0.001). Moreover, volumetric depletion progressed with time, being substantially pronounced at hatching compared to the embryonic stage. The volume changes were significant and were effectively quantified using Image-J.

  14. Methamphetamine-induced conditioned place preference in LG/J and SM/J mouse strains and an F45/F46 advanced intercross line.

    PubMed

    Bryant, Camron D; Kole, Loren A; Guido, Michael A; Cheng, Riyan; Palmer, Abraham A

    2012-01-01

    The conditioned place preference (CPP) test is frequently used to evaluate the rewarding properties of drugs of abuse in mice. Despite its widespread use in transgenic and knockout experiments, there are few forward genetic studies using CPP to identify novel genes contributing to drug reward. In this study, we tested LG/J and SM/J inbred strains and the parents/offspring of 10 families of an F(45)/F(46) advanced intercross line (AIL) for methamphetamine-induced CPP (MA-CPP) once per week over 2 weeks. Both LG/J and SM/J mice exhibited significant MA-CPP that was not significantly different between the two strains. Furthermore, LG/J mice showed significantly less acute MA-induced locomotor activity as well as locomotor sensitization following subsequent MA injections. AIL mice (N = 105) segregating LG/J and SM/J alleles also demonstrated significant MA-CPP that was equal in magnitude between the first and second week of training. Importantly, MA-CPP in AIL mice did not correlate with drug-free or MA-induced locomotor activity, indicating that MA-CPP was not confounded by test session activity and implying that MA-CPP is genetically distinct from acute psychomotor sensitivity. We estimated the heritability of MA-CPP and locomotor phenotypes using midparent-offspring regression and maximum likelihood estimates derived from the kinship coefficients of the AIL pedigree. Heritability estimates of MA-CPP were low (0-0.21) and variable (SE = 0-0.33) which reflected our poor power to estimate heritability using only 10 midparent-offspring observations. In sum, we established a short-term protocol for MA-CPP in AIL mice that could reveal LG/J and SM/J alleles important for MA reward. The use of highly recombinant genetic populations like AIL should facilitate the identification of these genes and may have implications for understanding psychostimulant abuse in humans.

  15. A high-fat diet differentially regulates glutathione phenotypes in the obesity-prone mouse strains DBA/2J, C57BL/6J, and AKR/J.

    PubMed

    Norris, Katie M; Okie, Whitney; Kim, Woo Kyun; Adhikari, Roshan; Yoo, Sarah; King, Stephanie; Pazdro, Robert

    2016-12-01

    The ubiquitous tripeptide glutathione (GSH) is a critical component of the endogenous antioxidant defense system. Tissue GSH concentrations and redox status (GSH/GSSG) are genetically controlled, but it is unclear whether interactions between genetic background and diet affect GSH homeostasis. The current study tested the hypothesis that a high-fat diet regulates GSH homeostasis in a manner dependent on genetic background. At 4 months of age, female mice representing 3 obesity-prone inbred strains-C57BL/6J (B6), DBA/2J (D2), and AKR/J (AKR)-were randomly assigned to consume a control (10% energy from fat) or high-fat (62% energy from fat) diet for 10 weeks (n=5/diet per strain). Tissue GSH levels, GSSG levels, and GSH/GSSG were quantified, and hepatic expression of GSH-related enzymes was evaluated by quantitative reverse transcription polymerase chain reaction. The high-fat diet caused a decrease in hepatic GSH/GSSG in D2 mice. In contrast, B6 mice exhibited a decrease in GSSG levels in the liver and kidney, as well as a resultant increase in renal GSH/GSSG. AKR mice also exhibited increased renal GSH/GSSG on a high-fat diet. Finally, the high-fat diet induced a unique gene expression response in D2 mice compared with B6 and AKR. The D2 response was characterized by up-regulation of glutamate-cysteine ligase modifier subunit and down-regulation of glutathione reductase, whereas the B6 and AKR responses were characterized by up-regulation of glutathione peroxidase 1. Two-way analysis of variance analyses confirmed several diet-strain interactions within the GSH system, and linear regression models highlighted relationships between body mass and GSH outcomes as well. Overall, our data indicate that dietary fat regulates the GSH system in a strain-dependent manner. Copyright © 2016 Elsevier Inc. All rights reserved.

  16. Partial dispensability of Djp1's J domain in peroxisomal protein import in Saccharomyces cerevisiae results from genetic redundancy with another class II J protein, Caj1.

    PubMed

    Dobriyal, Neha; Tripathi, Prerna; Sarkar, Susrita; Tak, Yogesh; Verma, Amit K; Sahi, Chandan

    2017-05-01

    J proteins are obligate co-chaperones of Hsp70s. Via their signature J domain, all J proteins interact with their partner Hsp70s and stimulate their weak ATPase activity, which is vital for Hsp70 functions. The dependency of J proteins on their J domain is such that mutations in critical amino acids in the J domain often results into a null phenotype for a particular J protein. Here, we show that the J domain of Djp1, a cytosolic J protein important for peroxisomal protein import in Saccharomyces cerevisiae, is partially dispensable. A complete deletion of Djp1 J domain resulted into only partial loss in peroxisomal protein import function. Instead, the C-terminal domain of Djp1 was found to be essential for proper localization of the peroxisomal targeted GFP-PTS1. Furthermore, we show that Caj1, another cytosolic J protein, also has some role in peroxisomal protein import. Caj1 was found to be partially redundant with Djp1 as cells lacking both Djp1 and Caj1 resulted into a much more severe defect in GFP-PTS1 localization. Based on these results, we propose that dispensability of J domains could be attributed to genetic redundancy between different J proteins sharing common structural topology and cellular localization.

  17. Systematic in J-PARC/Hyper-K

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Minamino, Akihiro

    The Hyper-Kamiokande (Hyper-K) detector is a next generation underground water Chrenkov detector. The J-PARC to Hyper-K experiment has good potential for precision measurements of neutrino oscillation parameters and discovery reach for CP violation in the lepton sector. With a total exposure of 10 years to a neutrino beam produced by the 750 kW J-PARC proton synchrotron, it is expected that the CP phase δ can be determined to better than 18 degree for all possible values of δ if sin{sup 2} 2θ{sub 13} > 0.03 and the mass hierarchy is known. Control of systematic uncertainties is critical to make maximummore » use of the Hyper-K potential. Based on learning from T2K experience, a strategy to reduce systematic uncertainties in J-PARC/Hyper-K are developed.« less

  18. FERMI LARGE AREA TELESCOPE DETECTION OF PULSED gamma-RAYS FROM THE VELA-LIKE PULSARS PSR J1048-5832 AND PSR J2229+6114

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Abdo, A. A.; Ackermann, M.; Ajello, M.

    2009-12-01

    We report the detection of gamma-ray pulsations (>=0.1 GeV) from PSR J2229+6114 and PSR J1048-5832, the latter having been detected as a low-significance pulsar by EGRET. Data in the gamma-ray band were acquired by the Large Area Telescope (LAT) aboard the Fermi Gamma-ray Space Telescope, while the radio rotational ephemerides used to fold the gamma-ray light curves were obtained using the Green Bank Telescope, the Lovell telescope at Jodrell Bank, and the Parkes Telescope. The two young radio pulsars, located within the error circles of the previously unidentified EGRET sources 3EG J1048-5840 and 3EG J2227+6122, present spin-down characteristics similar tomore » the Vela pulsar. PSR J1048-5832 shows two sharp peaks at phases 0.15 +- 0.01 and 0.57 +- 0.01 relative to the radio pulse confirming the EGRET light curve, while PSR J2229+6114 presents a very broad peak at phase 0.49 +- 0.01. The gamma-ray spectra above 0.1 GeV of both pulsars are fit with power laws having exponential cutoffs near 3 GeV, leading to integral photon fluxes of (2.19 +- 0.22 +- 0.32) x 10{sup -7} cm{sup -2} s{sup -1} for PSR J1048-5832 and (3.77 +- 0.22 +- 0.44) x 10{sup -7} cm{sup -2} s{sup -1} for PSR J2229+6114. The first uncertainty is statistical and the second is systematic. PSR J1048-5832 is one of the two LAT sources which were entangled together as 3EG J1048-5840. These detections add to the growing number of young gamma-ray pulsars that make up the dominant population of GeV gamma-ray sources in the Galactic plane.« less

  19. CYP101J2, CYP101J3, and CYP101J4, 1,8-Cineole-Hydroxylating Cytochrome P450 Monooxygenases from Sphingobium yanoikuyae Strain B2

    PubMed Central

    Unterweger, Birgit; Bulach, Dieter M.; Scoble, Judith; Midgley, David J.; Greenfield, Paul; Lyras, Dena; Johanesen, Priscilla

    2016-01-01

    ABSTRACT We report the isolation and characterization of three new cytochrome P450 monooxygenases: CYP101J2, CYP101J3, and CYP101J4. These P450s were derived from Sphingobium yanoikuyae B2, a strain that was isolated from activated sludge based on its ability to fully mineralize 1,8-cineole. Genome sequencing of this strain in combination with purification of native 1,8-cineole-binding proteins enabled identification of 1,8-cineole-binding P450s. The P450 enzymes were cloned, heterologously expressed (N-terminally His6 tagged) in Escherichia coli BL21(DE3), purified, and spectroscopically characterized. Recombinant whole-cell biotransformation in E. coli demonstrated that all three P450s hydroxylate 1,8-cineole using electron transport partners from E. coli to yield a product putatively identified as (1S)-2α-hydroxy-1,8-cineole or (1R)-6α-hydroxy-1,8-cineole. The new P450s belong to the CYP101 family and share 47% and 44% identity with other 1,8-cineole-hydroxylating members found in Novosphingobium aromaticivorans and Pseudomonas putida. Compared to P450cin (CYP176A1), a 1,8-cineole-hydroxylating P450 from Citrobacter braakii, these enzymes share less than 30% amino acid sequence identity and hydroxylate 1,8-cineole in a different orientation. Expansion of the enzyme toolbox for modification of 1,8-cineole creates a starting point for use of hydroxylated derivatives in a range of industrial applications. IMPORTANCE CYP101J2, CYP101J3, and CYP101J4 are cytochrome P450 monooxygenases from S. yanoikuyae B2 that hydroxylate the monoterpenoid 1,8-cineole. These enzymes not only play an important role in microbial degradation of this plant-based chemical but also provide an interesting route to synthesize oxygenated 1,8-cineole derivatives for applications as natural flavor and fragrance precursors or incorporation into polymers. The P450 cytochromes also provide an interesting basis from which to compare other enzymes with a similar function and expand the CYP101

  20. Verticalization of behavior elicited by dopaminergic mobilization is qualitatively different between C57BL/6J and DBA/2J mice.

    PubMed

    Tirelli, E; Witkin, J M

    1994-10-01

    Behavioral effects of dopaminergic stimulation were evaluated in C57BL/6J mice and compared to the effects occurring in DBA/2J mice, an inbred strain with reduced densities of striatal dopamine receptors. Effects of apomorphine (0.5-64 mg/kg) alone and in combination with cocaine (30 mg/kg) were assessed using a time-sampling technique that classified climbing and leaning in separate categories. Locomotion was also assessed in a separate experiment. Climbing occurred in DBA/2J mice only at doses of apomorphine that were 16 times higher than the smallest effective dose in C57BL/6J mice; nevertheless, relative to baseline values, effects were fairly comparable. By contrast, whereas DBA/2J mice showed dose-dependent leaning under apomorphine, C57BL/6J mice exhibited little leaning even at doses not producing climbing, and only after the highest apomorphine dose was leaning significantly increased. Apomorphine was equipotent in inducing gnawing across strains, although somewhat less efficacious in DBA/2J mice. When given alone, cocaine produced significant climbing, but not leaning or gnawing, in either strain. Whereas cocaine potentiated apomorphine-induced climbing and gnawing in both strains, apomorphine-induced leaning was not consistently changed by cocaine in either strain. These effects were not indirectly due to hyperkinesia, since neither apomorphine alone nor apomorphine and cocaine in combination was stimulant; apomorphine alone reduced locomotor activity and attenuated cocaine-induced hyperkinesia. The present data do not support a unitary, purely quantitative, account of insensitivity to dopaminergic stimulation based upon low densities of striatal dopamine receptors in DBA/2J mice. Rather, this constellation of results is suggestive of qualitative interstrain dissimilarities in dopaminergic responsiveness that could reflect organizational differences in receptor populations.

  1. Modeling the optical radiation of the precataclysmic variable SDSS J212531-010745

    NASA Astrophysics Data System (ADS)

    Shimansky, V. V.; Borisov, N. V.; Nurtdinova, D. N.; Solovyeva, Yu. N.; Sakhibullin, N. A.; Spiridonova, O. I.

    2015-03-01

    Optical observations are analyzed to derive a set of basic parameters for the precataclysmic variable star SDSS J212531-010745, whose primary is a PG1159-type star. Spectroscopic and multiband photometric observations of the star were performed in 2008-2011 with the 6-m telescope and the Zeiss-1000 telescope of the Special Astrophysical Observatory. The shape of the binary's orbital light curves is nearly sinusoidal, with the amplitude increasing with wavelength from Δ m = 0.40 m in the B band to Δ m = 0.73 m in the R band. The spectra contain absorption lines of HeII and neutral atoms, along with HI, HeI, CII, MgII, FeII emission lines, whose intensity increases synchronously with the brightness of the system. The optical radiation from SDSS J212531-010745 has a composite nature, corresponding to a model for a pre-cataclysmic variable with strong reflection effects. Cross-correlation techniques are used to measure the radial velocities and derive the component masses. Numerical modeling of the binary's light curves, radial velocities, and spectra is performed, and a complete set of parameters determined. Considerable abundance anomalies (to 1 dex) were detected for the secondary. The primary's characteristics correspond to the evolutionary predictions for DAO dwarfs with masses M ≈ 0.5 M ⊙, and the secondary's characteristics to low-mass, main-sequence stars with the solar metallicity.

  2. Clinical significance of J-wave in elite athletes.

    PubMed

    Pelliccia, Antonio; Quattrini, Filippo M

    2015-01-01

    The J-wave pattern on 12-lead ECG is traditionally defined as a positive deflection at junction between the end of the QRS and the beginning of the ST-segment. This pattern has recently been associated with increased risk for idiopathic ventricular fibrillation in the absence of cardiovascular disease. The interest for the clinical significance of J-wave pattern as a potential ECG hallmark of high risk for cardiac arrest has recently been reinforced by the growing practice of ECG screening, such as occurs in large population of young competitive athletes. The available scientific evidence shows that the J-wave pattern is relatively common in trained athletes (ranging from 14% to 44%) and, differently from subjects who suffered from ventricular fibrillation, commonly localized in lateral leads while it is relatively rare to be found in inferior leads. Furthermore the J-wave pattern has been demonstrated to be a dynamic phenomenon related to the training status, with the larger prominence at the peak of training and with an inverse relation between magnitude of J-wave and heart rate. In addition the J-wave pattern is usually associated with other ECG changes, such as increased QRS voltages and ST-segment elevation, as well as LV remodeling, suggesting that it likely represents another expression of the physiologic athlete's heart. Finally the scientific data available demonstrated that during a medium follow-up period the J-wave pattern does not convey risk for adverse cardiac events, including sudden death or ventricular tachyarrhythmias. Copyright © 2015 Elsevier Inc. All rights reserved.

  3. LAUNCH - STS-28/51J - KSC

    NASA Image and Video Library

    1985-11-20

    S85-44776 (3 Oct 1985) --- Space Shuttle Atlantis soars toward Florida blue skies to mark the maiden mission of NASA's fourth and newest orbiter vehicle. Launch occurred at 11:15 a.m. (EDT), October 3, 1985. A five member crew mans the orbiter for the DOD flight. They are Karol J. Bobko, Ronald J. Grabe, Robert L. Stewart, David C. Hilmers-- all of NASA-- and William A. Pailes of the USAF.

  4. GPR-derived architecture of jökulhlaup sediments, Gígjökull, Iceland

    NASA Astrophysics Data System (ADS)

    Harrison, Devin; Ross, Neil; Russell, Andrew; Dunning, Stuart

    2017-04-01

    A warming global climate has implications for glacial retreat and meltwater generation. In Iceland, the potential frequency and magnitude of jökulhlaup (glacial outburst flood) hazards from ice-dammed and moraine-dammed lakes may be increased by: (i) increased glacial meltwater production; and (ii) the glacio-isostatic response of the mantle driven by deglaciation, which is hypothesised to increase volcanic activity. The high peak-discharges of volcanically-induced jökulhlaups in Iceland have the ability to deposit significant volumes of sediment, causing major geomorphic change and societal impacts. Understanding geomorphological process associated with jökulhlaups can assist in predicting and evaluating future jökulhlaup behaviour and impacts. The 2010 Eyjafjallajökull eruption produced multiple jökulhlaups resulting in major sediment deposition and proglacial aggradation. Observations of the timing, scale and hydraulic properties of these jökulhlaups during the eruption have provided a unique opportunity to investigate the impact of ice-rich meltwater flows on the proglacial environment. Using low-frequency (40 MHz) ground penetrating radar (GPR) and differential GPS (dGPS) surveys of the Gígjökull basin, this study has: (1) geophysically characterised the thick sequence of sedimentary deposits associated with the Eyjafjallajökull eruption, to test conceptual models of jökulhlaup deposition; and (2) quantified post-depositional (2010-2016) elevation change, to evaluate the role of buried ice on post-jökulhlaup landscape response and recovery. The jökulhlaup deposits are characterised by three prominent sediment sub-units, delimited by strong continuous reflectors, and displaying discontinuous undulating reflections (indicating the presence of dunes or anti-dunes). The structures within these sub-units provide insight into the fluvial processes associated with multiple high-magnitude flood events and their relation to the hydraulic properties and

  5. 7 CFR Appendix J to Subpart E of... - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 14 2010-01-01 2009-01-01 true [Reserved] J Appendix J to Subpart E of Part 1980 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS...) PROGRAM REGULATIONS (CONTINUED) GENERAL Business and Industrial Loan Program Appendix J to Subpart E of...

  6. A PHOTOMETRIC STUDY OF FOUR RECENTLY DISCOVERED CONTACT BINARIES: 1SWASP J064501.21+342154.9, 1SWASP J155822.10-025604.8, 1SWASP J212808.86+151622.0, AND UCAC4 436-062932

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Djurašević, G.; Latković, O.; Cséki, A.

    We present new, high-quality multicolor observations of four recently discovered contact binaries, 1SWASP J064501.21+342154.9, 1SWASP J155822.10-025604.8, 1SWASP J212808.86+151622.0, and UCAC4 436-062932, and analyze their light curves to determine orbital and physical parameters using the modeling program of G. Djurašević. In the absence of spectroscopic observations, the effective temperatures of the brighter components are estimated from the color indices, and the mass ratios are determined with the q -search method. The analysis shows that all four systems are W UMa type binaries in shallow contact configurations, consisting of late-type main-sequence primaries and evolved secondaries with active surface regions (dark or bright spots) resultingmore » from magnetic activity or ongoing transfer of thermal energy between the components. We compare the derived orbital and stellar parameters for these four variables with a large sample of previously analyzed W UMa stars and find that our results fit it well.« less

  7. Spinon-Holon Attraction in the Supersymmetric t-J Model with 1/r

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bernevig, B. A.; Giuliano, D.; Laughlin, R. B.

    2001-10-22

    We derive the coordinate representation of the one-spinon one-holon wave function for the supersymmetric t-J model with 1/r{sup 2} interaction. This result allows us to show that a spinon and a holon attract each other at short distance. The attraction gets stronger as the size of the system is increased and, in the thermodynamic limit, it is responsible for the square-root singularity in the hole spectral function [Y. Kato, Phys.Rev.Lett.81, 5402 (1998)].

  8. On the Generalized Heisenberg Supermagnetic Model

    NASA Astrophysics Data System (ADS)

    Yan, Zhao-Wen; Zhang, Xiao-Jing; Han, Rong; Li, Chuan-Zhong

    2018-05-01

    In this paper, we construct the generalized Heisenberg supermagnetic models with two different constraints and investigate the integrability of the super integrable systems. By virtue of the gauge transformation, their corresponding gauge equivalent counterparts are derived, i.e., the super and fermionic mixed derivative nonlinear Schrödinger equations, respectively. Supported by National Natural Science Foundation of China under Grant Nos. 11605096, 11571192, and 11601247 and innovation Foundation of Inner Mongolia University for the College Students (201711208)

  9. 29 CFR 451.4 - Labor organizations under section 3(j).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 2 2010-07-01 2010-07-01 false Labor organizations under section 3(j). 451.4 Section 451.4... 1959 § 451.4 Labor organizations under section 3(j). (a) General. Section 3(j) sets forth five... one of these categories listed in section 3(j) is subject to the requirements of the Act. (b...

  10. The Arizona Radio Observatory CO Mapping Survey of Galactic Molecular Clouds. V. The Sh2-235 Cloud in CO J=2-1, 13CO J=2-1, and CO J=3-2

    NASA Astrophysics Data System (ADS)

    Bieging, John H.; Patel, Saahil; Peters, William L.; Toth, L. Viktor; Marton, Gábor; Zahorecz, Sarolta

    2016-09-01

    We present the results of a program to map the Sh2-235 molecular cloud complex in the CO and 13CO J = 2 - 1 transitions using the Heinrich Hertz Submillimeter Telescope. The map resolution is 38″ (FWHM), with an rms noise of 0.12 K brightness temperature, for a velocity resolution of 0.34 km s-1. With the same telescope, we also mapped the CO J = 3 - 2 line at a frequency of 345 GHz, using a 64 beam focal plane array of heterodyne mixers, achieving a typical rms noise of 0.5 K brightness temperature with a velocity resolution of 0.23 km s-1. The three spectral line data cubes are available for download. Much of the cloud appears to be slightly sub-thermally excited in the J = 3 level, except for in the vicinity of the warmest and highest column density areas, which are currently forming stars. Using the CO and 13CO J = 2 - 1 lines, we employ an LTE model to derive the gas column density over the entire mapped region. Examining a 125 pc2 region centered on the most active star formation in the vicinity of Sh2-235, we find that the young stellar object surface density scales as approximately the 1.6-power of the gas column density. The area distribution function of the gas is a steeply declining exponential function of gas column density. Comparison of the morphology of ionized and molecular gas suggests that the cloud is being substantially disrupted by expansion of the H II regions, which may be triggering current star formation.

  11. J-2X engine

    NASA Image and Video Library

    2012-05-16

    On May 16, 2012, engineers at Stennis Space Center conducted a test of the next-generation J-2X engine that will help power NASA's new Space Launch System, moving NASA even closer to a return to deep space.

  12. Measurement of prompt J/Ψ pair production in pp collisions at √s = 7 TeV

    DOE PAGES

    Khachatryan, Vardan

    2014-09-17

    Production of prompt J/ψ meson pairs in proton-proton collisions at √s = 7 TeV is measured with the CMS experiment at the LHC in a data sample corresponding to an integrated luminosity of about 4.7 fb -1. The two J/ψ mesons are fully reconstructed via their decays into μ + μ - pairs. This observation provides for the first time access to the high-transverse-momentum region of J/ψ pair production where model predictions are not yet established. The total and differential cross sections are measured in a phase space defined by the individual J/ψ transverse momentum (p T J/ψ ) andmore » rapidity (|y J/ψ |): |y J/ψ | < 1.2 for p T J/ψ > 6.5 GeV/c; 1.2 < |y J/ψ | < 1.43 for a p T threshold that scales linearly with |y J/ψ | from 6.5 to 4.5 GeV/c; and 1.43 < |y J/ψ | < 2.2 for p T J/ψ > 4.5 GeV/c. The total cross section, assuming unpolarized prompt J/ψ pair production is 1.49 ± 0.07 (stat) ±0.13 (syst) nb. Different assumptions about the J/ψ polarization imply modifications to the cross section ranging from -31% to +27%.« less

  13. A BABAR sensitivity study on the search for the invisible decay of J/psi in B+/- mesons going to K*+/- J/psi

    NASA Astrophysics Data System (ADS)

    Cheaib, Racha

    We present a sensitivity study on the search for J/psi → nu nu in B+/- → K*+/- J/psi using data from the BABAR experiment at the SLAC National Accelerator Laboratory. The decay is highly suppressed in the Standard Model and thus is a possible window for new physics such as supersymmetry and dark matter. Hadronic tag reconstruction is employed for the analysis, where one B is fully reconstructed using hadronic decay modes. The remaining tracks and clusters are attributed to the signal B on which the B+/- → K*+/- J/psi cut-based signal selection is applied. The associated K* is allowed to decay via two modes, Mode 1: K* +/- → K0S pi+/- and Mode 2: K* +/- → K+/- pi 0. The approach is to reconstruct a K*+/- candidate, the only signature in a signal event, and calculate the recoiling mass. The data is left blinded in the signal region and only a range of the branching fraction limits is calculated to determine the sensitivity. The result for Mode 1 is an upper limit, at the 90% confidence level, on B (J/psi → nunu) of 9.13 x 10-2 using the Barlow method and 11.10 x 10-2 using the Feldmann-Cousins method. The upper limit for Mode 2, also at the 90% CL, is estimated to be 2.49 x 10-2 and 2.98 x 10-2 using Barlow and Feldmann-Cousins respectively. The branching fractions thus yield a sensitivity of order 10-2. Although the result is not an improvement on the current J/psi → nu nu limits, this method can be extended to other cc¯ quarkonium modes and could further yield a much better result with data from the newly approved SuperB experiment, the extension of BABAR to higher luminosities.

  14. Chandra Observations of the Field Containing HESS J1616-508

    NASA Astrophysics Data System (ADS)

    Hare, Jeremy; Kargaltsev, Oleg; Pavlov, George G.; Rangelov, Blagoy; Volkov, Igor

    2017-06-01

    We report the results of three Chandra observations covering most of the extent of the TeV γ-ray source HESS J1616-508 and a search for a lower-energy counterpart to this source. We detect 56 X-ray sources, 37 of which have counterparts at lower frequencies, including a young massive star cluster, but none of them appear to be a particularly promising counterpart to the TeV source. The brightest X-ray source, CXOU J161423.4-505738, with a flux F 0.5-7 keV ≈ 5 × 10-13 erg cm-2 s-1, has a hard spectrum that is well fit by a power-law model with a photon index Γ = 0.2 ± 0.3 and is a likely intermediate polar CV candidate. No counterparts of this source were detected at other wavelengths. CVs are not known to produce extended TeV emission, and the source is also largely offset (19‧) from HESS J1616-508, making them unlikely to be associated. We have also set an upper limit on the X-ray flux of PSR J1614-5048 in the 0.5-8 keV band (F 0.5-8 keV < 5 × 10-15 erg cm-2 s-1 at a 90% confidence level). This makes PSR J1614-5048 one of the least X-ray-efficient pulsars known, with an X-ray efficiency {η }0.5{--8{keV}}={L}0.5{--8{keV}}/\\dot{E}< 2× {10}-5. We find no evidence supporting the association between the pulsar and the TeV source. We rule out a number of X-ray sources as possible counterparts to the TeV emission and do not find a plausible counterpart among the other sources. Lastly, we discuss the possible relation of PSR J1617-5055 to HESS J1616-508 in light of the new observations.

  15. Exosomes carring gag/env of ALV-J possess negative effect on immunocytes.

    PubMed

    Wang, Guihua; Wang, Zhenzhen; Zhuang, Pingping; Zhao, Xiaomin; Cheng, Ziqiang

    2017-11-01

    J subgroup avian leukosis virus (ALV-J) is an exogenous retrovirus of avian. A key feature of ALV-J infection is leading to severe immunosuppressive characteristic of diseases. Viral components of retrovirus were reported closely associated with immunosuppression, and several similarities between exosomes and retrovirus preparations have lead to the hypotheses of retrovirus hijacker exosomes pathway. In this study, we purified exosomes from DF-1 cells infected and uninfected by ALV-J. Electron microscopy and mass spectrometry (MS) analysis showed that ALV-J not only increased the production of exosomes from ALV-J infected DF-1 cells (Exo-J) but also stimulated some proteins expression, especially ALV-J components secreted in exosomes. Immunosuppressive domain peptide (ISD) of envelope subunit transmembrane (TM) and gag of ALV-J were secreted in Exo-J. It has been reported that HIV gag was budded from endosome-like domains of the T cell plasma membrane. But env protein was first detected in exosomes from retrovirus infected cells. We found that Exo-J caused negative effects on splenocytes in a dose-dependant manner by flow cytometric analysis. And low dose of Exo-J activated immune activity of splenocytes, while high dose possessed immunosuppressive properties. Interestingly, Exo-J has no significant effects on the immunosuppression induced by ALV-J, and the immunosuppressive effects induced by Exo-J lower than that by ALV-J. Taken together, our data indicated that Exo-J supplied a microenvironment for the replication and transformation of ALV-J. Copyright © 2017. Published by Elsevier Ltd.

  16. Re J (A Minor) (Wardship: Medical Treatment)

    PubMed

    1992-06-10

    The Civil Division of England's Court of Appeal overturned the lower court's order of mechanical ventilation for a profoundly handicapped sixteen-month-old child against the clinical judgment of the child's doctors. Since hitting his head in a fall at age four weeks, J had not mentally developed past that time and he was blind and he suffered from severe cerebral palsy and epilepsy. He required nasogastric tubal feeding and, although he occasionally responded to sound, whether or not he recognized his caregivers was uncertain. His divorced mother and the local authority shared parental authority over J, who resided with foster parents. The consultant pediatrician reported that if J were to suffer a life-threatening event, ordinary resuscitation, antibiotics and physiotherapy would be appropriate, but intervention with intensive measures including mechanical ventilation would be medically inappropriate. Two other specialists agreed with those findings, but another consultant found mechanical ventilation not to be cruel and thought J could be weaned from it if it became so. The mother and local health authority asked the court to require the health authority to continue all treatment, including mechanical ventilation, of J. The Official Solicitor and the health authority opposed such an order. The lower court granted an interim order requiring mechanical ventilation if necessary over the five weeks prior to the main hearing. The appellate court viewed such an order as an abuse of judicial power and held that the physician's duty to the patient is to treat with the necessary consent in accord with the best clinical judgment and that, as long as those with parental authority consent to J's treatment by the health authority, he must be treated in accord with the best clinical judgment of that authority's personnel.

  17. J functions for the process ud→WA

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bardin, D. Yu., E-mail: bardin@nu.jinr.ru; Kalinovskaya, L. V., E-mail: kalinov@mail.cern.ch; Uglov, E. D., E-mail: e.uglov@gmail.com

    In this paper we present a description of the universal approach for analytic calculations for a certain class of J functions for six topologies of the boxes for the process ud → WA. These functions J arise at the reduction of the infrared divergent box diagrams. The standard Passarino–Veltman reduction of the four-point box diagram with an internal photon line connecting two external lines on the mass shell leads to infrared-divergent and mass-singular D{sub 0} functions. In the system SANC a systematic procedure is adopted to separate both types of singularities into the simplest objects, namely C{sub 0} functions. Themore » functions J, in turn, are represented as certain linear combinations of the standard D{sub 0} and C{sub 0} functions. The subtracted J functions are free of both types of singularities and are expressed as explicit and compact linear combinations of dilogarithm functions. We present extensive comparisons of numerical results of SANC with those obtained with the aid of the LoopTools package.« less

  18. jà vu phenomenon-related EEG pattern. Case report.

    PubMed

    Vlasov, P N; Chervyakov, A V; Gnezditskii, V V

    2013-01-01

    jà vu (DV, from French déjà vu - "already seen") is an aberration of psychic activity associated with transitory erroneous perception of novel circumstances, objects, or people as already known. This study aimed to record the EEG pattern of déjà vu. The subjects participated in a survey concerning déjà vu characteristics and underwent ambulatory EEG monitoring (12-16 h). In patients with epilepsy, DV episodes began with polyspike activity in the right temporal lobe region and, in some cases, ended with slow-wave theta-delta activity over the right hemisphere. There were no epileptic discharges in healthy respondents during DV. Two types of déjà vu are suggested to exist: "pathological-epileptic" déjà vu, characteristic of patients with epilepsy and equivalent to an epileptic seizure, and "nonpathological-nonepileptic" déjà vu, which is characteristic of healthy people and psychological phenomenon.

  19. Update on J /ψ regeneration in a hadron gas

    NASA Astrophysics Data System (ADS)

    Abreu, L. M.; Khemchandani, K. P.; Torres, A. Martínez; Navarra, F. S.; Nielsen, M.

    2018-04-01

    In heavy-ion collisions, after the quark-gluon plasma there is a hadronic gas phase. Using effective Lagrangians, we study the interactions of charmed mesons which lead to J /ψ production and absorption in this gas. We update and extend previous calculations introducing strange meson interactions and also including the interactions mediated by the recently measured exotic charmonium resonances Z (3900 ) and Z (4025 ) . These resonances open new reaction channels for the J /ψ , which could potentially lead to changes in its multiplicity. We compute the J /ψ production cross section in processes such as D(s) (*)+D¯(*)→J /ψ +(π ,ρ ,K ,K*) and also the J /ψ absorption cross section in the corresponding inverse processes. Using the obtained cross sections as input to solve the appropriate rate equation, we conclude that the interactions in the hadron gas phase lead to a 20-24% reduction of the J /ψ abundance. Within the uncertainties of the calculation, this reduction is the same at the Relativistic Heavy Ion Collider and the large Hadron Collider.

  20. jà Vu Experiences in Healthy Czech Adults.

    PubMed

    Lacinová, Lenka; Neužilová Michalčáková, Radka; Širůček, Jan; Ježek, Stanislav; Chromec, Jakub; Masopustová, Zuzana; Urbánek, Tomáš; Brázdil, Milan

    2016-12-01

    The study examines the prevalence of déjà vu in healthy Czech adults and explores its relationships with a number of variables: age, sex, neuroticism, depression, the degree of irritability in the limbic system, perceived stress, and finally attachment avoidance and anxiety. The participants were 365 healthy adults ranging from 18 to 70 years recruited in the Czech Republic (mean age = 29.05; SD = 11.17) who filled out online questionnaires. Déjà vu experiences were reported by 324 (88.8%) of them. Persons who experienced déjà vu were younger than the persons who had not experienced it. We found that sex, levels of neuroticism, depression, perceived stress, and attachment did not serve as predictors of experiences of déjà vu phenomena. Finally, those who had reported déjà vu experiences reported more limbic system irritability symptoms. We discuss the possibility that déjà vu reports together with other studied variables mainly reflect the participants' willingness to report "extraordinal" experiences.

  1. Spin-symmetry conversion and internal rotation in high J molecular systems

    NASA Astrophysics Data System (ADS)

    Mitchell, Justin; Harter, William

    2006-05-01

    Dynamics and spectra of molecules with internal rotation or rovibrational coupling is approximately modeled by rigid or semi-rigid rotors with attached gyroscopes. Using Rotational Energy (RE)^1 surfaces, high resolution molecular spectra for high angular momentum show two distinct but related phenomena; spin-symmetry conversion and internal rotation. For both cases the high total angular momentum allows for transitions that would otherwise be forbidden. Molecular body-frame J-localization effects associated with tight energy level-clusters dominate the rovibronic spectra of high symmetry molecules, particularly spherical tops at J>10. ^2 The effects include large and widespread spin-symmetry mixing contrary to conventional wisdom^3 about weak nuclear moments. Such effects are discussed showing how RE surface plots may predict them even at low J. Classical dynamics of axially constrained rotors are approximated by intersecting rotational-energy-surfaces (RES) that have (J-S).B.(J-S) forms in the limit of constraints that do no work. Semi-classical eigensolutions are compared to those found by direct diagonalization. ^1 W.G Hater, in Handbook of Atomic, Molecular and Optical Physics, edited by G.W.F Drake (Springer, Germany 2006) ^2 W. G. Harter, Phys. Rev. A24,192-262(1981). ^3 G. Herzberg, Infrared and Raman Spectra (VanNostrand 1945) pp. 458,463.

  2. Extinction, seeing and sky transparency monitoring at the Observatorio Astrofísico de Javalambre for J-PAS and J-PLUS calibration and scheduling

    NASA Astrophysics Data System (ADS)

    Vázquez Ramió, H.; Díaz-Martín, M. C.; Varela, J.; Ederoclite, A.; Maícas, N. Lamadrid, J. L.; Abril, J.; Iglesias-Marzoa, R.; Rodríguez, S.; Tilve, V.; Cenarro, A. J.; Antón Bravo, J. L.; Bello Ferrer, R.; Cristóbal-Hornillos, D.; Guillén Civera, L.; Hernández-Fuertes, J.; Jiménez Mejías, D.; Lasso-Cabrera, N. M.; López Alegre, G.; López Sainz, A.; Luis-Simoes, R. M.; Marín-Franch, A.; Moles, M.; Rueda-Teruel, F.; Rueda-Teruel, S.; Suárez López, O.; Yanes-Díaz, A.

    2015-05-01

    The Javalambre-Physics of the Accelerating Universe Astrophysical Survey (J-PAS; see Benítez et al. 2014) and the Javalambre-Photometric Local Universe Survey (J-PLUS) will be conducted at the brand-new Observatorio Astrofísico de Javalambre (OAJ) in Teruel, Spain. J-PLUS is planned to start by the first half of 2015 while J-PAS first light is expected to happen along 2015. Besides the two main telescopes (with 2.5 m and 80 cm apertures), several smaller-sized facilities are present at the OAJ devoted to site characterization and supporting measurements to be used to calibrate the J-PAS and J-PLUS photometry and to feed up the OAJ's Sequencer with the integrated seeing and the sky transparency. These instruments are: i) an extinction monitor, an 11 " telescope estimating the atmospheric extinction to finally obtain the OAJ extinction curve, which is the initial step to J-PAS overall photometric calibration procedure; ii) an 8 " telescope implementing the Differential Image Motion Monitor (DIMM) technique to obtain the integrated seeing; and iii) an All-Sky Transmission MONitor (ASTMON), a roughly all-sky instrument providing the sky transparency as well as sky brightness and the atmospheric extinction too.

  3. Fermi Large Area Telescope observations of the supernova remnant HESS J1731-347

    NASA Astrophysics Data System (ADS)

    Yang, Rui-zhi; Zhang, Xiao; Yuan, Qiang; Liu, Siming

    2014-07-01

    Context. HESS J1731-347 has been identified as one of the few TeV-bright shell-type supernova remnants (SNRs). These remnants are dominated by nonthermal emission, and the nature of TeV emission has been continuously debated for nearly a decade. Aims: We carry out the detailed modeling of the radio to γ-ray spectrum of HESS J1731-347 to constrain the magnetic field and energetic particles sources, which we compare with those of the other TeV-bright shell-type SNRs explored before. Methods: Four years of data from Fermi Large Area Telescope (LAT) observations for regions around this remnant are analyzed, leading to no detection correlated with the source discovered in the TeV band. The Markov chain Monte Carlo method is used to constrain parameters of one-zone models for the overall emission spectrum. Results: Based on the 99.9% upper limits of fluxes in the GeV range, one-zone hadronic models with an energetic proton spectral slope greater than 1.8 can be ruled out, which favors a leptonic origin for the γ-ray emission, making this remnant a sibling of the brightest TeV SNR RX J1713.7-3946, the Vela Junior SNR RX J0852.0-4622, and RCW 86. The best-fit leptonic model has an electron spectral slope of 1.8 and a magnetic field of ~30 μG, which is at least a factor of 2 higher than those of RX J1713.7-3946 and RX J0852.0-4622, posing a challenge to the distance estimate and/or the energy equipartition between energetic electrons and the magnetic field of this source. A measurement of the shock speed will address this challenge and has implications on the magnetic field evolution and electron acceleration driven by shocks of SNRs.

  4. 7. Historic American Buildings Survey Photocopy c. 1923 from J. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Historic American Buildings Survey Photocopy c. 1923 from J. J. Glessner The Story of a House FIRST FLOOR STAIRHALL: SOUTH - John J. Glessner House, 1800 South Prairie Avenue, Chicago, Cook County, IL

  5. 19 CFR 134.33 - J-List exceptions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... with the provisions of section 304(a)(3)(J), Tariff Act of 1930, as amended (19 U.S.C. 1304(a)(3)(J... indicate the origin of its contents in accordance with the requirements of subpart C of this part. All articles are listed in Treasury Decisions 49690, 49835, and 49896. A reference different from the foregoing...

  6. 19 CFR 134.33 - J-List exceptions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... with the provisions of section 304(a)(3)(J), Tariff Act of 1930, as amended (19 U.S.C. 1304(a)(3)(J... indicate the origin of its contents in accordance with the requirements of subpart C of this part. All articles are listed in Treasury Decisions 49690, 49835, and 49896. A reference different from the foregoing...

  7. 8. Historic American Buildings Survey Photocopy c. 1923 from J. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Historic American Buildings Survey Photocopy c. 1923 from J. J. Glessner The Story of a House LIBRARY: WEST AND NORTH SIDES - John J. Glessner House, 1800 South Prairie Avenue, Chicago, Cook County, IL

  8. Upgrade of absolute extreme ultraviolet diagnostic on J-TEXT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, X. L.; Cheng, Z. F., E-mail: chengfe@hust.edu.cn; Hou, S. Y.

    The absolute extreme ultraviolet (AXUV) diagnostic system is used for radiation observation on J-TEXT tokamak [J. Zhang, G. Zhuang, Z. J. Wang, Y. H. Ding, X. Q. Zhang, and Y. J. Tang, Rev. Sci. Instrum. 81, 073509 (2010)]. The upgrade of the AXUV system is aimed to improve the spatial resolution and provide a three-dimensional image on J-TEXT. The new system consists of 12 AXUV arrays (4 AXUV16ELG arrays, 8 AXUV20ELG arrays). The spatial resolution in the cross-section is 21 mm for the AXUV16ELG arrays and 17 mm for the AXUV20ELG arrays. The pre-amplifier is also upgraded for a highermore » signal to noise ratio. By upgrading the AXUV imaging system, a more accurate observation on the radiation information is obtained.« less

  9. Performance analysis of a miniature Joule-Thomson cryocooler with and without the distributed J-T effect

    NASA Astrophysics Data System (ADS)

    Damle, Rashmin; Atrey, Milind

    2015-12-01

    Cryogenic temperatures are obtained with Joule-Thomson (J-T) cryocoolers in an easier way as compared to other cooling techniques. Miniature J-T cryocoolers are often employed for cooling of infrared sensors, cryoprobes, biological samples, etc. A typical miniature J-T cryocooler consists of a storage reservoir/compressor providing the high pressure gas, a finned tube recuperative heat exchanger, an expansion valve/orifice, and the cold end. The recuperative heat exchanger is indispensable for attaining cryogenic temperatures. The geometrical parameters and the operating conditions of the heat exchanger drastically affect the cryocooler performance in terms of cool down time and cooling effect. In the literature, the numerical models for the finned recuperative heat exchanger have neglected the distributed J-T effect. The distributed J-T effect accounts for the changes in enthalpy of the fluid due to changes of pressure in addition to those due to changes of temperature. The objective of this work is to explore the distributed J-T effect and study the performance of a miniature J-T cryocooler with and without the distributed J-T effect. A one dimensional transient model is employed for the numerical analysis of the cryocooler. Cases with different operating conditions are worked out with argon and nitrogen as working fluids.

  10. 11. Historic American Buildings Survey Photocopy c. 1923 from J. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. Historic American Buildings Survey Photocopy c. 1923 from J. J. Glessner The Story of a House UPPER HALL - NORTH AND WEST SIDES - John J. Glessner House, 1800 South Prairie Avenue, Chicago, Cook County, IL

  11. 10. Historic American Buildings Survey Photocopy c. 1923 from J. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. Historic American Buildings Survey Photocopy c. 1923 from J. J. Glessner The Story of a House DINING ROOM: WEST AND NORTH SIDES - John J. Glessner House, 1800 South Prairie Avenue, Chicago, Cook County, IL

  12. Spectral Properties of Composite Excitations in the t-J Model

    NASA Astrophysics Data System (ADS)

    Otaki, Takashi; Yahagi, Yuta; Matsueda, Hiroaki

    2017-08-01

    In quantum many-body systems, the equation of motion for a simple fermionic operator does not close, and higher-order processes induce composite operators dressed with several types of nonlocal quantum fluctuation. We systematically examine the spectral properties of these composite excitations in the t-J model in one spatial dimension by both numerical and theoretical approaches. Of particular interest, with the help of the Bethe ansatz for the large-U Hubbard model, is the classification of which composite excitations are due to the string excitation, which is usually hidden in the single-particle spectrum, as well as the spinon and holon branches. We examine how the mixing between the spinon and string excitations is prohibited in terms of the composite operator method. Owing to the dimensionality independent nature of the present approach, we discuss the implications of the mixing in close connection with the pseudogap in high-Tc cuprates.

  13. Confirming the gamma-ray blazar nature of the low energy counterpart QSO GB6 J1604+5714 of 2FGL J1604.6+5710 with WISE

    NASA Astrophysics Data System (ADS)

    Massaro, F.; D'Abrusco, R.; Paggi, A.

    2012-06-01

    Following the rapid optical variability detected in the QSO GB6 J1604+5714 (=BZQJ1604+5714) (ATEL #4184), associated to the gamma-ray source 2FGL J1604.6+5710 (=1FGL J1604.3+5710) in Nolan et al. (2012 ApJS, 199, 31), we searched in the Wide-field Infrared Survey Explorer (WISE; Wright et al. 2010 AJ, 140, 1868) catalog at the VLBI position of the QSO GB6 J1604+5714 (R.A.(J2000): 16h04m37.3546s, Dec.(J2000): +57d14m36.660s) reported in Beasley et al......

  14. 6. Historic American Buildings Survey Photocopy c. 1923 from J. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Historic American Buildings Survey Photocopy c. 1923 from J. J. Glessner The Story of a House FIRST FLOOR STAIRCASE: MAIN HALL NORTH END - John J. Glessner House, 1800 South Prairie Avenue, Chicago, Cook County, IL

  15. Quantum influence in the criticality of the spin- {1}/{2} anisotropic Heisenberg model

    NASA Astrophysics Data System (ADS)

    Ricardo de Sousa, J.; Araújo, Ijanílio G.

    1999-07-01

    We study the spin- {1}/{2} anisotropic Heisenberg antiferromagnetic model using the effective field renormalization group (EFRG) approach. The EFRG method is illustrated by employing approximations in which clusters with one ( N'=1) and two ( N=2) spins are used. The dependence of the critical temperature Tc (ferromagnetic-F case) and TN (antiferromagnetic-AF case) and thermal critical exponent, Yt, are obtained as a function of anisotropy parameter ( Δ) on a simple cubic lattice. We find that, in our results, TN is higher than Tc for the quantum anisotropic Heisenberg limit and TN= Tc for the Ising and quantum XY limits. We have also shown that the thermal critical exponent Yt for the isotropic Heisenberg model shows a small dependence on the type of interaction (F or AF) due to finite size effects.

  16. Final science results: Spacelab J

    NASA Technical Reports Server (NTRS)

    Leslie, Fred (Editor)

    1995-01-01

    This report contains a brief summary of the mission science conducted aboard Spacelab J (SL-J), a joint venture between the National Aeronautics and Space Administration (NASA) and the National Space Development Agency (NASDA) of Japan. The scientific objectives of the mission were to conduct a variety of material and life science experiments utilizing the weightlessness and radiation environment of an orbiting Spacelab. All 43 experiments were activated; 24 in microgravity sciences (material processing, crystal growth, fluid physics, and acceleration measurement) and 19 in life sciences (physiology, developmental biology, radiation effects, separation processes, and enzyme crystal growth). In addition, more than a dozen experiments benefited from the extra day through either additional experiment runs or extended growth time.

  17. XTE J1946+274 = GRO J1944+26: An Enigmatic Be/X-ray Binary

    NASA Technical Reports Server (NTRS)

    Wilson, Colleen A.; Finger, Mark H.; Coe, M. J.; Negueruela, Ignacio; Six, N. Frank (Technical Monitor)

    2002-01-01

    XTE J1946+274 = GRO J1944+26 is a 15.8-s Be/X-ray pulsar discovered simultaneously in 1998 September with the, Burst and Transient Source Experiment (BATSE) on the Compton Gamma Ray Observatory (CGRO) and the All-Sky Monitor (ASM) on the Rossi X-ray Timing Explorer (RXTE). Pulse timing analysis yielded an orbital period of 169.2 days, a moderate eccentricity of 0.33, and implied a mass function of 9.7 solar mass. We observed evidence for an accretion disk, a correlation between measured spin-up rate and flux, which was fitted to obtain a distance estimate of 9.2 +/- 1.0 kpc. XTE J1946+274 remained active from 1998 September - 2001 July, undergoing 13 outbursts that were not locked in orbital phase. Comparing RXTE PCA observations from the initial bright outburst in 1998 and the last pair of outburst in 2001, we found energy and intensity dependent pulse profile variations in both outbursts and hardening spectra with increasing intensity during the fainter 2001 outbursts. In 2001 July, optical H(alpha) observations indicate a density perturbation appeared in the Be disk as the X-ray outbursts ceased. We propose that the equatorial plane of the Be star is inclined with respect to the orbital plane in this system and that this inclination may produce the unusual outburst behavior of the system.

  18. 4. Historic American Buildings Survey Photocopy c. 1923 from J. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Historic American Buildings Survey Photocopy c. 1923 from J. J. Glessner The Story of a House DETAIL: GABLE AND CHIMNEY 18th STREET SIDE - John J. Glessner House, 1800 South Prairie Avenue, Chicago, Cook County, IL

  19. Dalitz plot analyses of J / ψ → π + π - π 0 , J / ψ → K + K - π 0 , and J / ψ → K s 0 K ± π ∓ produced via e + e - annihilation with initial-state radiation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lees, J. P.; Poireau, V.; Tisserand, V.

    We study the processes e + e - → γ ISR J / ψ , where J / ψ → π + π - π 0 , J / ψ → K + K - π 0 , and J / ψ → Kmore » $$0\\atop{S}$$ K ± π ∓ using a data sample of 519 fb - 1 recorded with the BABAR detector operating at the SLAC PEP-II asymmetric-energy e + e - collider at center-of-mass energies at and near the Υ ( n S ) ( n = 2 , 3 , 4 ) resonances.« less

  20. A Possible Magnetar Nature for IGR J16358-4726

    NASA Technical Reports Server (NTRS)

    Patel, S.; Zurita, J.; DelSanto, M.; Finger, M.; Koueliotou, C.; Eichler, D.; Gogus, E.; Ubertini, P.; Walter, R.; Woods, P.

    2006-01-01

    We present detailed spectral and timing analysis of the hard x-ray transient IGR J16358-4726 using multi-satellite archival observations. A study of the source flux time history over 6 years, suggests that this transient outbursts can be occurring in intervals of at most 1 year. Joint spectral fits using simultaneous Chandra/ACIS and INTEGRAL/ISGRI data reveal a spectrum well described by an absorbed cut-off power law model plus an Fe line. We detected the pulsations initially reported using Chandra/ACIS also in the INTEGRAL/ISGRI light curve and in subsequent XMM-Newton observations. Using the INTEGRAL data we identified a pulse spin up of 94 s (P = 1.6 x 10(exp -4), which strongly points to a neutron star nature for IGR J16358-4726. Assuming that the spin up is due to disc accretion, we estimate that the source magnetic field ranges between 10(sup 13) approximately 10(sup 15) depending on its distance, possibly supporting a magnetar nature for IGR J16358-4726.

  1. A Possible Magnetar Nature for IGR J16358-4726

    NASA Technical Reports Server (NTRS)

    Patel, S. K.; Zurita, J.; DelSanto, M.; Finger, M.; Kouveliotou, C.; Eichler, D.; Gogus, E.; Ubertini, P.; Walter, R.; Woods, P.; hide

    2007-01-01

    We present detailed spectral and timing analysis of the hard X-ray transient IGR J16358-4726 using multisatellite archival observations. A study of the source flux time history over 6 yr suggests that lower luminosity transient outbursts can be occurring in intervals of at most 1 yr. Joint spectral fits of the higher luminosity outburst using simultaneous Chandra ACIS and INTEGRAL ISGRI data reveal a spectrum well described by an absorbed power-law model with a high-energy cutoff plus an Fe line. We detected the 1.6 hr pulsations initially reported using Chandra ACIS also in the INTEGRAL ISGRI light curve and in subsequent XMM-Newton observations. Using the INTEGRAL data, we identified a spin-up of 94 s (P(sup(.)) = 1.6 x 10(exp -4), which strongly points to a neutron star nature for IGR J16358-4726. Assuming that the spin-up is due to disk accretion, we estimate that the source magnetic field ranges between 10(exp 13) and 10(exp 15) G, depending on its distance, possibly supporting a magnetar nature for IGR J16358-4726.

  2. Redox-active tyrosine residue in the microcin J25 molecule

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chalon, Miriam C.; Wilke, Natalia; Pedersen, Jens

    2011-03-18

    Research highlights: {yields} Cyclic voltammetry measurements showed irreversible oxidation of MccJ25 and MccJ25 (Y9F). {yields} Infrared spectroscopy studies showed that only Tyr9 could be deprotonated upon chemical oxidation. {yields} Formation of a long-lived tyrosyl radical in the native MccJ25 oxidized by H{sub 2}O{sub 2} was demonstrated. {yields} Tyr9 but not Tyr20 can be easily oxidized and form a tyrosyl radical. -- Abstract: Microcin J25 (MccJ25) is a 21 amino acid lasso-peptide antibiotic produced by Escherichia coli and composed of an 8-residues ring and a terminal 'tail' passing through the ring. We have previously reported two cellular targets for this antibiotic,more » bacterial RNA polymerase and the membrane respiratory chain, and shown that Tyr9 is essential for the effect on the membrane respiratory chain which leads to superoxide overproduction. In the present paper we investigated the redox behavior of MccJ25 and the mutant MccJ25 (Y9F). Cyclic voltammetry measurements showed irreversible oxidation of both Tyr9 and Tyr20 in MccJ25, but infrared spectroscopy studies demonstrated that only Tyr9 could be deprotonated upon chemical oxidation in solution. Formation of a long-lived tyrosyl radical in the native MccJ25 oxidized by H{sub 2}O{sub 2} was demonstrated by Electron Paramagnetic Resonance Spectroscopy; this radical was not detected when the reaction was carried out with the MccJ25 (Y9F) mutant. These results show that the essential Tyr9, but not Tyr20, can be easily oxidized and form a tyrosyl radical.« less

  3. Persistent psychogenic déjà vu: a case report.

    PubMed

    Wells, Christine E; Moulin, Chris J A; Ethridge, Paige; Illman, Nathan A; Davies, Emma; Zeman, Adam

    2014-12-08

    jà vu is typically a transient mental state in which a novel experience feels highly familiar. Although extensively studied in relation to temporal lobe epilepsy as part of simple partial seizures, déjà vu has been less studied in other clinical populations. A recent review of temporal lobe epilepsy suggested a possible link between clinical levels of anxiety and debilitating déjà vu, indicating further research is required. Here, for the first time in the literature, we present a case study of a young man with anxiety and depersonalisation who reported experiencing persistent and debilitating déjà vu. This report therefore adds to the limited literature on the relationship between anxiety and déjà vu. A 23-year-old White British man presented with a form of persistent déjà vu in 2010, approximately 3 years since symptom onset. He reported a history of anxiety and experiencing feelings of depersonalisation. Neurological assessment (electroencephalogram and magnetic resonance imaging) did not indicate any abnormalities. We assessed his recognition memory with a task used in patients with dementia who report similar experiences but lack awareness of their falseness. Our case's memory performance was more conservative than controls but did not indicate a memory deficit. Unlike other patients with chronic déjà vu (for example, in dementia), he is fully aware of the false nature of his déjà vu and this presumably leads to his intact recognition memory performance. We suggest that his persistent déjà vu is psychogenic and conclude that déjà vu should be further studied in psychiatric disorders.

  4. AtomicJ: An open source software for analysis of force curves

    NASA Astrophysics Data System (ADS)

    Hermanowicz, Paweł; Sarna, Michał; Burda, Kvetoslava; Gabryś, Halina

    2014-06-01

    We present an open source Java application for analysis of force curves and images recorded with the Atomic Force Microscope. AtomicJ supports a wide range of contact mechanics models and implements procedures that reduce the influence of deviations from the contact model. It generates maps of mechanical properties, including maps of Young's modulus, adhesion force, and sample height. It can also calculate stacks, which reveal how sample's response to deformation changes with indentation depth. AtomicJ analyzes force curves concurrently on multiple threads, which allows for high speed of analysis. It runs on all popular operating systems, including Windows, Linux, and Macintosh.

  5. Modelling the flaring activity of the high-z, hard X-ray-selected blazar IGR J22517+2217: Flaring activity of IGR J22517+2217

    DOE PAGES

    Lanzuisi, G.; De Rosa, A.; Ghisellini, G.; ...

    2012-03-21

    We present new Suzaku and Fermi data and re-analysed archival hard X-ray data from the INTErnational Gamma-Ray Astrophysics Laboratory (INTEGRAL) and Swift–Burst Alert Telescope (BAT) surveys to investigate the physical properties of the luminous, high-redshift, hard X-ray-selected blazar IGR J22517+2217, through the modelling of its broad-band spectral energy distribution (SED) in two different activity states. Through analysis of new Suzaku data and flux-selected data from archival hard X-ray observations, we build the source SED in two different states, one for the newly discovered flare that occurred in 2005 and one for the following quiescent period. Both SEDs are strongly dominatedmore » by the high-energy hump peaked at 10 20–10 22 Hz, which is at least two orders of magnitude higher than the low-energy (synchrotron) one at 10 11–10 14 Hz and varies by a factor of 10 between the two states. In both states the high-energy hump is modelled as inverse Compton emission between relativistic electrons and seed photons produced externally to the jet, while the synchrotron self-Compton component is found to be negligible. In our model the observed variability can be accounted for by a variation of the total number of emitting electrons and by a dissipation region radius changing from inside to outside the broad-line region as the luminosity increases. In its flaring activity, IGR J22517+2217 is revealed as one of the most powerful jets among the population of extreme, hard X-ray-selected, high-redshift blazars observed so far.« less

  6. jà vu phenomenon-related EEG pattern. Case report☆

    PubMed Central

    Vlasov, P.N.; Chervyakov, A.V.; Gnezditskii, V.V.

    2013-01-01

    Background Déjà vu (DV, from French déjà vu — “already seen”) is an aberration of psychic activity associated with transitory erroneous perception of novel circumstances, objects, or people as already known. Objective This study aimed to record the EEG pattern of déjà vu. Methods The subjects participated in a survey concerning déjà vu characteristics and underwent ambulatory EEG monitoring (12–16 h). Results In patients with epilepsy, DV episodes began with polyspike activity in the right temporal lobe region and, in some cases, ended with slow-wave theta–delta activity over the right hemisphere. There were no epileptic discharges in healthy respondents during DV. Conclusion Two types of déjà vu are suggested to exist: “pathological-epileptic” déjà vu, characteristic of patients with epilepsy and equivalent to an epileptic seizure, and “nonpathological-nonepileptic” déjà vu, which is characteristic of healthy people and psychological phenomenon. PMID:25667847

  7. Evidence for Exotic Hadron Contributions to Λb0→J /ψ p π- Decays

    NASA Astrophysics Data System (ADS)

    Aaij, R.; Abellán Beteta, C.; Adeva, B.; Adinolfi, M.; Ajaltouni, Z.; Akar, S.; Albrecht, J.; Alessio, F.; Alexander, M.; Ali, S.; Alkhazov, G.; Alvarez Cartelle, P.; Alves, A. A.; Amato, S.; Amerio, S.; Amhis, Y.; An, L.; Anderlini, L.; Andreassi, G.; Andreotti, M.; Andrews, J. E.; Appleby, R. B.; Aquines Gutierrez, O.; Archilli, F.; d'Argent, P.; Arnau Romeu, J.; Artamonov, A.; Artuso, M.; Aslanides, E.; Auriemma, G.; Baalouch, M.; Bachmann, S.; Back, J. J.; Badalov, A.; Baesso, C.; Baldini, W.; Barlow, R. J.; Barschel, C.; Barsuk, S.; Barter, W.; Batozskaya, V.; Battista, V.; Bay, A.; Beaucourt, L.; Beddow, J.; Bedeschi, F.; Bediaga, I.; Bel, L. J.; Bellee, V.; Belloli, N.; Belous, K.; Belyaev, I.; Ben-Haim, E.; Bencivenni, G.; Benson, S.; Benton, J.; Berezhnoy, A.; Bernet, R.; Bertolin, A.; Bettler, M.-O.; van Beuzekom, M.; Bifani, S.; Billoir, P.; Bird, T.; Birnkraut, A.; Bitadze, A.; Bizzeti, A.; Blake, T.; Blanc, F.; Blouw, J.; Blusk, S.; Bocci, V.; Boettcher, T.; Bondar, A.; Bondar, N.; Bonivento, W.; Borghi, S.; Borisyak, M.; Borsato, M.; Bossu, F.; Boubdir, M.; Bowcock, T. J. V.; Bowen, E.; Bozzi, C.; Braun, S.; Britsch, M.; Britton, T.; Brodzicka, J.; Buchanan, E.; Burr, C.; Bursche, A.; Buytaert, J.; Cadeddu, S.; Calabrese, R.; Calvi, M.; Calvo Gomez, M.; Campana, P.; Campora Perez, D.; Capriotti, L.; Carbone, A.; Carboni, G.; Cardinale, R.; Cardini, A.; Carniti, P.; Carson, L.; Carvalho Akiba, K.; Casse, G.; Cassina, L.; Castillo Garcia, L.; Cattaneo, M.; Cauet, Ch.; Cavallero, G.; Cenci, R.; Charles, M.; Charpentier, Ph.; Chatzikonstantinidis, G.; Chefdeville, M.; Chen, S.; Cheung, S.-F.; Chobanova, V.; Chrzaszcz, M.; Cid Vidal, X.; Ciezarek, G.; Clarke, P. E. L.; Clemencic, M.; Cliff, H. V.; Closier, J.; Coco, V.; Cogan, J.; Cogneras, E.; Cogoni, V.; Cojocariu, L.; Collazuol, G.; Collins, P.; Comerma-Montells, A.; Contu, A.; Cook, A.; Coquereau, S.; Corti, G.; Corvo, M.; Costa Sobral, C. M.; Couturier, B.; Cowan, G. A.; Craik, D. C.; Crocombe, A.; Cruz Torres, M.; Cunliffe, S.; Currie, R.; D'Ambrosio, C.; Dall'Occo, E.; Dalseno, J.; David, P. N. Y.; Davis, A.; De Aguiar Francisco, O.; De Bruyn, K.; De Capua, S.; De Cian, M.; De Miranda, J. M.; De Paula, L.; De Simone, P.; Dean, C.-T.; Decamp, D.; Deckenhoff, M.; Del Buono, L.; Demmer, M.; Derkach, D.; Deschamps, O.; Dettori, F.; Dey, B.; Di Canto, A.; Dijkstra, H.; Dordei, F.; Dorigo, M.; Dosil Suárez, A.; Dovbnya, A.; Dreimanis, K.; Dufour, L.; Dujany, G.; Dungs, K.; Durante, P.; Dzhelyadin, R.; Dziurda, A.; Dzyuba, A.; Déléage, N.; Easo, S.; Egede, U.; Egorychev, V.; Eidelman, S.; Eisenhardt, S.; Eitschberger, U.; Ekelhof, R.; Eklund, L.; Elsasser, Ch.; Ely, S.; Esen, S.; Evans, H. M.; Evans, T.; Falabella, A.; Farley, N.; Farry, S.; Fay, R.; Ferguson, D.; Fernandez Albor, V.; Ferrari, F.; Ferreira Rodrigues, F.; Ferro-Luzzi, M.; Filippov, S.; Fiore, M.; Fiorini, M.; Firlej, M.; Fitzpatrick, C.; Fiutowski, T.; Fleuret, F.; Fohl, K.; Fontana, M.; Fontanelli, F.; Forshaw, D. C.; Forty, R.; Frank, M.; Frei, C.; Frosini, M.; Fu, J.; Furfaro, E.; Färber, C.; Gallas Torreira, A.; Galli, D.; Gallorini, S.; Gambetta, S.; Gandelman, M.; Gandini, P.; Gao, Y.; García Pardiñas, J.; Garra Tico, J.; Garrido, L.; Garsed, P. J.; Gascon, D.; Gaspar, C.; Gavardi, L.; Gazzoni, G.; Gerick, D.; Gersabeck, E.; Gersabeck, M.; Gershon, T.; Ghez, Ph.; Gianı, S.; Gibson, V.; Girard, O. G.; Giubega, L.; Gizdov, K.; Gligorov, V. V.; Golubkov, D.; Golutvin, A.; Gomes, A.; Gorelov, I. V.; Gotti, C.; Grabalosa Gándara, M.; Graciani Diaz, R.; Granado Cardoso, L. A.; Graugés, E.; Graverini, E.; Graziani, G.; Grecu, A.; Griffith, P.; Grillo, L.; Gruberg Cazon, B. R.; Grünberg, O.; Gushchin, E.; Guz, Yu.; Gys, T.; Göbel, C.; Hadavizadeh, T.; Hadjivasiliou, C.; Haefeli, G.; Haen, C.; Haines, S. C.; Hall, S.; Hamilton, B.; Han, X.; Hansmann-Menzemer, S.; Harnew, N.; Harnew, S. T.; Harrison, J.; He, J.; Head, T.; Heister, A.; Hennessy, K.; Henrard, P.; Henry, L.; Hernando Morata, J. A.; van Herwijnen, E.; Heß, M.; Hicheur, A.; Hill, D.; Hombach, C.; Hulsbergen, W.; Humair, T.; Hushchyn, M.; Hussain, N.; Hutchcroft, D.; Idzik, M.; Ilten, P.; Jacobsson, R.; Jaeger, A.; Jalocha, J.; Jans, E.; Jawahery, A.; John, M.; Johnson, D.; Jones, C. R.; Joram, C.; Jost, B.; Jurik, N.; Kandybei, S.; Kanso, W.; Karacson, M.; Kariuki, J. M.; Karodia, S.; Kecke, M.; Kelsey, M.; Kenyon, I. R.; Kenzie, M.; Ketel, T.; Khairullin, E.; Khanji, B.; Khurewathanakul, C.; Kirn, T.; Klaver, S.; Klimaszewski, K.; Koliiev, S.; Kolpin, M.; Komarov, I.; Koopman, R. F.; Koppenburg, P.; Kozachuk, A.; Kozeiha, M.; Kravchuk, L.; Kreplin, K.; Kreps, M.; Krokovny, P.; Kruse, F.; Krzemien, W.; Kucewicz, W.; Kucharczyk, M.; Kudryavtsev, V.; Kuonen, A. K.; Kurek, K.; Kvaratskheliya, T.; Lacarrere, D.; Lafferty, G.; Lai, A.; Lambert, D.; Lanfranchi, G.; Langenbruch, C.; Langhans, B.; Latham, T.; Lazzeroni, C.; Le Gac, R.; van Leerdam, J.; Lees, J.-P.; Leflat, A.; Lefrançois, J.; Lefèvre, R.; Lemaitre, F.; Lemos Cid, E.; Leroy, O.; Lesiak, T.; Leverington, B.; Li, Y.; Likhomanenko, T.; Lindner, R.; Linn, C.; Lionetto, F.; Liu, B.; Liu, X.; Loh, D.; Longstaff, I.; Lopes, J. H.; Lucchesi, D.; Lucio Martinez, M.; Luo, H.; Lupato, A.; Luppi, E.; Lupton, O.; Lusiani, A.; Lyu, X.; Machefert, F.; Maciuc, F.; Maev, O.; Maguire, K.; Malde, S.; Malinin, A.; Maltsev, T.; Manca, G.; Mancinelli, G.; Manning, P.; Maratas, J.; Marchand, J. F.; Marconi, U.; Marin Benito, C.; Marino, P.; Marks, J.; Martellotti, G.; Martin, M.; Martinelli, M.; Martinez Santos, D.; Martinez Vidal, F.; Martins Tostes, D.; Massacrier, L. M.; Massafferri, A.; Matev, R.; Mathad, A.; Mathe, Z.; Matteuzzi, C.; Mauri, A.; Maurin, B.; Mazurov, A.; McCann, M.; McCarthy, J.; McNab, A.; McNulty, R.; Meadows, B.; Meier, F.; Meissner, M.; Melnychuk, D.; Merk, M.; Michielin, E.; Milanes, D. A.; Minard, M.-N.; Mitzel, D. S.; Molina Rodriguez, J.; Monroy, I. A.; Monteil, S.; Morandin, M.; Morawski, P.; Mordà, A.; Morello, M. J.; Moron, J.; Morris, A. B.; Mountain, R.; Muheim, F.; Mulder, M.; Mussini, M.; Müller, D.; Müller, J.; Müller, K.; Müller, V.; Naik, P.; Nakada, T.; Nandakumar, R.; Nandi, A.; Nasteva, I.; Needham, M.; Neri, N.; Neubert, S.; Neufeld, N.; Neuner, M.; Nguyen, A. D.; Nguyen-Mau, C.; Niess, V.; Nieswand, S.; Niet, R.; Nikitin, N.; Nikodem, T.; Novoselov, A.; O'Hanlon, D. P.; Oblakowska-Mucha, A.; Obraztsov, V.; Ogilvy, S.; Okhrimenko, O.; Oldeman, R.; Onderwater, C. J. G.; Otalora Goicochea, J. M.; Otto, A.; Owen, P.; Oyanguren, A.; Pais, P. R.; Palano, A.; Palombo, F.; Palutan, M.; Panman, J.; Papanestis, A.; Pappagallo, M.; Pappalardo, L. L.; Pappenheimer, C.; Parker, W.; Parkes, C.; Passaleva, G.; Patel, G. D.; Patel, M.; Patrignani, C.; Pearce, A.; Pellegrino, A.; Penso, G.; Pepe Altarelli, M.; Perazzini, S.; Perret, P.; Pescatore, L.; Petridis, K.; Petrolini, A.; Petrov, A.; Petruzzo, M.; Picatoste Olloqui, E.; Pietrzyk, B.; Pikies, M.; Pinci, D.; Pistone, A.; Piucci, A.; Playfer, S.; Plo Casasus, M.; Poikela, T.; Polci, F.; Poluektov, A.; Polyakov, I.; Polycarpo, E.; Pomery, G. J.; Popov, A.; Popov, D.; Popovici, B.; Potterat, C.; Price, E.; Price, J. D.; Prisciandaro, J.; Pritchard, A.; Prouve, C.; Pugatch, V.; Puig Navarro, A.; Punzi, G.; Qian, W.; Quagliani, R.; Rachwal, B.; Rademacker, J. H.; Rama, M.; Ramos Pernas, M.; Rangel, M. S.; Raniuk, I.; Raven, G.; Redi, F.; Reichert, S.; dos Reis, A. C.; Remon Alepuz, C.; Renaudin, V.; Ricciardi, S.; Richards, S.; Rihl, M.; Rinnert, K.; Rives Molina, V.; Robbe, P.; Rodrigues, A. B.; Rodrigues, E.; Rodriguez Lopez, J. A.; Rodriguez Perez, P.; Rogozhnikov, A.; Roiser, S.; Romanovskiy, V.; Romero Vidal, A.; Ronayne, J. W.; Rotondo, M.; Ruf, T.; Ruiz Valls, P.; Saborido Silva, J. J.; Sadykhov, E.; Sagidova, N.; Saitta, B.; Salustino Guimaraes, V.; Sanchez Mayordomo, C.; Sanmartin Sedes, B.; Santacesaria, R.; Santamarina Rios, C.; Santimaria, M.; Santovetti, E.; Sarti, A.; Satriano, C.; Satta, A.; Saunders, D. M.; Savrina, D.; Schael, S.; Schiller, M.; Schindler, H.; Schlupp, M.; Schmelling, M.; Schmelzer, T.; Schmidt, B.; Schneider, O.; Schopper, A.; Schubiger, M.; Schune, M.-H.; Schwemmer, R.; Sciascia, B.; Sciubba, A.; Semennikov, A.; Sergi, A.; Serra, N.; Serrano, J.; Sestini, L.; Seyfert, P.; Shapkin, M.; Shapoval, I.; Shcheglov, Y.; Shears, T.; Shekhtman, L.; Shevchenko, V.; Shires, A.; Siddi, B. G.; Silva Coutinho, R.; Silva de Oliveira, L.; Simi, G.; Sirendi, M.; Skidmore, N.; Skwarnicki, T.; Smith, E.; Smith, I. T.; Smith, J.; Smith, M.; Snoek, H.; Sokoloff, M. D.; Soler, F. J. P.; Souza, D.; Souza De Paula, B.; Spaan, B.; Spradlin, P.; Sridharan, S.; Stagni, F.; Stahl, M.; Stahl, S.; Stefko, P.; Stefkova, S.; Steinkamp, O.; Stenyakin, O.; Stevenson, S.; Stoica, S.; Stone, S.; Storaci, B.; Stracka, S.; Straticiuc, M.; Straumann, U.; Sun, L.; Sutcliffe, W.; Swientek, K.; Syropoulos, V.; Szczekowski, M.; Szumlak, T.; T'Jampens, S.; Tayduganov, A.; Tekampe, T.; Tellarini, G.; Teubert, F.; Thomas, C.; Thomas, E.; van Tilburg, J.; Tisserand, V.; Tobin, M.; Tolk, S.; Tomassetti, L.; Tonelli, D.; Topp-Joergensen, S.; Toriello, F.; Tournefier, E.; Tourneur, S.; Trabelsi, K.; Traill, M.; Tran, M. T.; Tresch, M.; Trisovic, A.; Tsaregorodtsev, A.; Tsopelas, P.; Tully, A.; Tuning, N.; Ukleja, A.; Ustyuzhanin, A.; Uwer, U.; Vacca, C.; Vagnoni, V.; Valat, S.; Valenti, G.; Vallier, A.; Vazquez Gomez, R.; Vazquez Regueiro, P.; Vecchi, S.; van Veghel, M.; Velthuis, J. J.; Veltri, M.; Veneziano, G.; Venkateswaran, A.; Vesterinen, M.; Viaud, B.; Vieira, D.; Vieites Diaz, M.; Vilasis-Cardona, X.; Volkov, V.; Vollhardt, A.; Voneki, B.; Voong, D.; Vorobyev, A.; Vorobyev, V.; Voß, C.; de Vries, J. A.; Vázquez Sierra, C.; Waldi, R.; Wallace, C.; Wallace, R.; Walsh, J.; Wang, J.; Ward, D. R.; Wark, H. M.; Watson, N. K.; Websdale, D.; Weiden, A.; Whitehead, M.; Wicht, J.; Wilkinson, G.; Wilkinson, M.; Williams, M.; Williams, M. P.; Williams, M.; Williams, T.; Wilson, F. F.; Wimberley, J.; Wishahi, J.; Wislicki, W.; Witek, M.; Wormser, G.; Wotton, S. A.; Wraight, K.; Wright, S.; Wyllie, K.; Xie, Y.; Xu, Z.; Yang, Z.; Yin, H.; Yu, J.; Yuan, X.; Yushchenko, O.; Zangoli, M.; Zarebski, K. A.; Zavertyaev, M.; Zhang, L.; Zhang, Y.; Zhang, Y.; Zhelezov, A.; Zheng, Y.; Zhokhov, A.; Zhukov, V.; Zucchelli, S.; LHCb Collaboration

    2016-08-01

    A full amplitude analysis of Λb0→J /ψ p π- decays is performed with a data sample acquired with the LHCb detector from 7 and 8 TeV p p collisions, corresponding to an integrated luminosity of 3 fb-1. A significantly better description of the data is achieved when, in addition to the previously observed nucleon excitations N →p π-, either the Pc(4380 )+ and Pc(4450)+→J/ψp states, previously observed in Λb0→J /ψ p K- decays, or the Zc(4200)-→J /ψ π-state, previously reported in B0→J /ψ K+π- decays, or all three, are included in the amplitude models. The data support a model containing all three exotic states, with a significance of more than three standard deviations. Within uncertainties, the data are consistent with the Pc(4380)+ and Pc(4450)+ production rates expected from their previous observation taking account of Cabibbo suppression.

  8. Evaluation of a simple model of ethanol drinking to intoxication in C57BL/6J mice.

    PubMed

    Rhodes, Justin S; Best, Karyn; Belknap, John K; Finn, Deborah A; Crabbe, John C

    2005-01-31

    Because of intrinsic differences between humans and mice, no single mouse model can represent all features of a complex human trait such as alcoholism. It is therefore necessary to develop partial models. One important feature is drinking to the point where blood ethanol concentration (BEC) reaches levels that have measurable affects on physiology and/or behavior (>1.0 mg ethanol/ml blood). Most models currently in use examine relative oral self-administration from a bottle containing alcohol versus one containing water (two-bottle preference drinking), or oral operant self-administration. In these procedures, it is not clear when or if the animals drink to pharmacologically significant levels because the drinking is episodic and often occurs over a 24-h period. The aim of this study was to identify the optimal parameters and evaluate the reliability of a very simple procedure, taking advantage of a mouse genotype (C57BL/6J) that is known to drink large quantities of ethanol. We exchanged for the water bottle a solution containing ethanol in tap water for a limited period, early in the dark cycle, in the home cage. Mice regularly drank sufficient ethanol to achieve BEC>1.0 mg ethanol/ml blood. The concentration of ethanol offered (10%, 20% or 30%) did not affect consumption in g ethanol/kg body weight. The highest average BEC ( approximately 1.6 mg/ml) occurred when the water-to-ethanol switch occurred 3 h into the dark cycle, and when the ethanol was offered for 4 rather than 2 h. Ethanol consumption was consistent within individual mice, and reliably predicted BEC after the period of ethanol access. C57BL/6J mice from three sources provided equivalent data, while DBA/2J mice drank much less than C57BL/6J in this test. We discuss advantages of the model for high-throughput screening assays where the goal is to find other genotypes of mice that drink excessively, or to screen drugs for their efficacy in blocking excessive drinking.

  9. Recurring déjà vu associated with 5-hydroxytryptophan.

    PubMed

    Kalra, Seema; Chancellor, Andrew; Zeman, Adam

    2007-10-01

    jà vu occurs both in normal experience and as a neuropsychiatric symptom. Its pathogenesis is partially understood. We describe an iatrogenic case with implications for the neuropharmacological basis of déjà vu. A 42-year-old woman received 5-hydroxytryptophan, in combination with carbidopa, as treatment for palatal tremor, on two occasions, separated by 1 week. On each occasion, she experienced intense, protracted déjà vu, lasting for several hours. We discuss her case in relation to the neuroanatomical and neuropharmacological basis of déjà vu. The serotonergic system is involved in the genesis of déjà vu.

  10. Spectralon solar diffuser BRDF variation for NPP, JPSS J1 and J2

    NASA Astrophysics Data System (ADS)

    Murgai, Vijay; Johnson, Lindsay; Klein, Staci

    2017-09-01

    The Visible/Infrared Imaging Radiometer Suite (VIIRS) is a key sensor on the Suomi National Polar-orbiting Partnership (NPP) satellite as well as the upcoming Joint Polar Satellite System (JPSS). VIIRS collects Earth radiometric and imagery data in 22 spectral bands from 0.4 to 12.5 μm. Radiometric calibration of the reflective bands in the 0.4 to 2.5 μm wavelength range is performed by measuring the sunlight reflectance from Spectralon®. Reflected sun light is directly proportional to the Bidirectional Reflectance Distribution Function (BRDF) of the Spectralon. This paper presents the BRDF measurements of the Spectralon for JPSS J2 in the 0.4 - 1.63 μm wavelength using PASCAL (Polarization And Scatter Characterization Analysis of Lambertian materials) with an uncertainty better than 1.2%. PASCAL makes absolute measurements of the BRDF in an analogous fashion to the National Institute of Standards and Technology (NIST) Spectral Tri-function Automated Reflectance Reflectometer (STARR) facility. Unique additional features of this instrument include the ability to vary the sample elevation and roll / clock the sample about its normal, allowing measurement of BRDF in the as used geometry. Comparison of BRDF in the as used configuration for NPP, J1, and J2 shows variation of up to 3%. The sign of the change from panel to panel depends on the angle of incidence and view angle. The results demonstrate lot to lot variability in Spectralon and emphasize the necessity of characterizing each panel. A pattern in the BRDF variation is also presented.

  11. J-2X Fuel Turbopump Point of Departure: The Performance of the J-2s Fuel Turbopump Inducer

    NASA Technical Reports Server (NTRS)

    Sargent, S. R.; Becht, D. G.; Mulder, A. D.

    2008-01-01

    To aid the J-2X program design effort with detailed performance and environment information, the J-2S fuel turbopump (FTP) inducer has undergone a thorough test series in both water and hydrogen. The test series utilizes both inducer only and a complete pump configuration to assess the inducer interaction to the overall turbopump system. The test goals include verification of suction performance against heritage J-2S data, head production, effects of thermodynamic suppression head (TSH), and evaluation of the inducer dynamic pressure caused by cavitation instabilities. Test facilities at both Pratt & Whitney Rocketdyne (PWR) and NASA s Stennis Space Center (SSC) are employed for the testing. The inducer only water test effort conducted at PWR established performance curves for suction performance, head production, and efficiency over a wide operating range. Because the heritage J-2S suction performance data set is in hydrogen, it is desired to obtain current suction performance data in hydrogen as well, thus avoiding the reliance on a theoretical TSH correlation for direct comparison. This data then provides an empirically based TSH correlation allowing for the comparison of water test suction data to system suction requirements. The FTP testing performed at SSC provides these suction performance relationships as well as inlet duct dynamic pressures during liquid hydrogen operation. The test effort successfully confirms the heritage J-2S suction performance and establishes the amount of TSH between water and hydrogen operation at the design flow coefficient. Correlating data is also obtained for cavitating instability frequency content, illustrating the validity of using the wide flow range water test data to predict hydrogen performance.

  12. Uncovering the Putative B-Star Binary Companion of the SN 1993J Progenitor

    NASA Technical Reports Server (NTRS)

    Fox, Ori D.; Bostroem, K. Azalee; Van Dyk, Schuyler D.; Filippenko, Alexei V.; Fransson, Claes; Matheson, Thomas; Cenko, S. Bradley; Chandra, Poonam; Dwarkadas, Vikram; Li, Weidong; hide

    2014-01-01

    The Type IIb supernova (SN) 1993J is one of only a few stripped-envelope SNe with a progenitor star identified in pre-explosion images. SN IIb models typically invoke H envelope stripping by mass transfer in a binary system. For the case of SN 1993J, the models suggest that the companion grew to 22 solar mass and became a source of ultraviolet (UV) excess. Located in M81, at a distance of only 3.6 Mpc, SN 1993J offers one of the best opportunities to detect the putative companion and test the progenitor model. Previously published near-UV spectra in 2004 showed evidence for absorption lines consistent with a hot (B2 Ia) star, but the field was crowded and dominated by flux from the SN. Here we present Hubble Space Telescope Cosmic Origins Spectrograph and Wide-Field Camera 3 observations of SN 1993J from 2012, at which point the flux from the SN had faded sufficiently to potentially measure the UV continuum properties from the putative companion. The resulting UV spectrum is consistent with contributions from both a hot B star and the SN, although we cannot rule out line-of-sight coincidences.

  13. Measurement of the ratio of the production cross sections times branching fractions of $$B_{c}^{\\pm} \\to J/\\psi \\pi^{\\pm}$$ and $$B^{\\pm} \\to J/\\psi K^{\\pm}$$ and $$\\mathcal{B}(B_{c}^{\\pm} \\to J/\\psi \\pi^{\\pm}\\pi^{\\pm}\\pi^{\\mp})/\\mathcal{B}(B_{c}^{\\pm} \\to J/\\psi \\pi^{\\pm})$$ in pp collisions at $$\\sqrt{s} =$$ 7 TeV

    DOE PAGES

    Khachatryan, Vardan

    2015-01-13

    The ratio of the production cross sections times branching fractions (σ(B ± c)B(B ± c→J/ψπ ±))/(σ(B ±)B(B ±→J/ψK ±)) is studied in proton-proton collisions at a center of-mass energy of 7 TeV with the CMS detector at the LHC. The kinematic region investigated requires B c ± and B ± mesons with transverse momentum p T > 15 GeV and rapidity |y|< 1.6. The data sample corresponds to an integrated luminosity of 5.1 fb -1. The ratio is determined to be [0.48±0.05(stat)± 0.03(syst)±0.05 (τBc)]%. The B c ± → J/ψπ ± π ± π ∓ decay is also observedmore » in the same data sample. Using a model-independent method developed to measure the efficiency given the presence of resonant behaviour in the three-pion system, the ratio of the branching fractions B(B ± c→J/ψπ ±π ±π ∓)/B(B ± c→J/ψπ ±) is measured to be 2.55±0.80(stat)±0.33(syst) +0.04 -0.01(τ Bc), consistent with the previous LHCb result.« less

  14. Measurement of the ratio of the production cross sections times branching fractions of $$B_{c}^{\\pm} \\to J/\\psi \\pi^{\\pm}$$ and $$B^{\\pm} \\to J/\\psi K^{\\pm}$$ and $$\\mathcal{B}(B_{c}^{\\pm} \\to J/\\psi \\pi^{\\pm}\\pi^{\\pm}\\pi^{\\mp})/\\mathcal{B}(B_{c}^{\\pm} \\to J/\\psi \\pi^{\\pm})$$ in pp collisions at $$\\sqrt{s} =$$ 7 TeV

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Khachatryan, Vardan

    The ratio of the production cross sections times branching fractions (σ(B ± c)B(B ± c→J/ψπ ±))/(σ(B ±)B(B ±→J/ψK ±)) is studied in proton-proton collisions at a center of-mass energy of 7 TeV with the CMS detector at the LHC. The kinematic region investigated requires B c ± and B ± mesons with transverse momentum p T > 15 GeV and rapidity |y|< 1.6. The data sample corresponds to an integrated luminosity of 5.1 fb -1. The ratio is determined to be [0.48±0.05(stat)± 0.03(syst)±0.05 (τBc)]%. The B c ± → J/ψπ ± π ± π ∓ decay is also observedmore » in the same data sample. Using a model-independent method developed to measure the efficiency given the presence of resonant behaviour in the three-pion system, the ratio of the branching fractions B(B ± c→J/ψπ ±π ±π ∓)/B(B ± c→J/ψπ ±) is measured to be 2.55±0.80(stat)±0.33(syst) +0.04 -0.01(τ Bc), consistent with the previous LHCb result.« less

  15. Unveiling the origin of HESS J1809-193

    NASA Astrophysics Data System (ADS)

    Castelletti, G.; Giacani, E.; Petriella, A.

    2016-03-01

    Aims: The main goal of this paper is to provide new insights on the origin of the observable flux of γ rays from HESS J1809-193 using new high-quality observations in the radio domain. Methods: We used the Expanded Very Large Array (now known as the Karl G. Jansky Very large Array, JVLA) to produce a deep full-synthesis imaging at 1.4 GHz of the vicinity of PSR J1809-1917. These data were used in conjunction with 12CO observations from the James Clerk Maxwell Telescope in the transition line J = 3-2 and atomic hydrogen data from the Southern Galactic Plane Survey to investigate the properties of the interstellar medium in the direction of the source HESS J1809-193. Results: The new radio continuum image, obtained with a synthesized beam of 8'' × 4'' and a sensitivity of 0.17 mJy beam-1, reveals with unprecedented detail all the intensity structures in the field. No radio counterpart to the observed X-ray emission supposed to be a pulsar wind nebula powered by PSR J1809-1917 is seen in the new JVLA image. We discovered a system of molecular clouds on the edge of the supernova remnant (SNR) G11.0-0.0 shock front, which is positionally coincident with the brightest part of the TeV source HESS J1809-193. We determine, on the basis of kinematic and morphological evidences, a physical link of the SNR with the clouds for which we estimated a total (molecular plus atomic) mass of ~3 × 103M⊙ and a total proton density in the range 2-3 × 103 cm-3. Conclusions: We propose as the most likely origin of the very high-energy γ-ray radiation from HESS J1809-193 a hadronic mechanism through collisions of ions accelerated at the SNR G11.0-0.0 shock with the molecular matter in the vicinity of the remnant. The new JVLA image (in FITS format) is only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/587/A71

  16. Nature of the Unidentified TeV Source HESS J1614-518 Revealed by Suzaku and XMM-Newton Observations

    NASA Astrophysics Data System (ADS)

    Sakai, M.; Yajima, Y.; Matsumoto, H.

    2013-03-01

    We report new results concerning HESS J1614-518, which exhibits two regions with intense γ-ray emission. The south and center regions of HESS J1614-518 were observed with Suzaku in 2008, while the north region with the 1st brightest peak was observed in 2006. No X-ray counterpart is found at the 2nd brightest peak; the upper limit of the X-ray flux is estimated as 1.6 × 10-13 erg cm-2 s-1 in the 2-10 keV band. A previously-known soft X-ray source, Suzaku J1614-5152, is detected at the center of HESS J1614-518. Analyzing the XMM-Newton archival data, we reveal that Suzaku J1614-5152 consists of multiple point sources. The X-ray spectrum of the brightest point source, XMMU J161406.0-515225, could be described by a power-law model with the photon index Γ = 5.2+0.6-0.5 or a blackbody model with the temperature kT = 0.38+0.04-0.04 {keV}. In the blackbody model, the estimated column density N H = 1.1+0.3-0.2 × 1022 {cm}-2 is almost the same as that of the hard extended X-ray emission in Suzaku J1614-5141, spatially coincident with the 1st peak position. In this case, XMMU J161406.0-515225 may be physically related to Suzaku J1614-5141 and HESS J1614-518.

  17. Rhinal-hippocampal interactions during déjà vu.

    PubMed

    Bartolomei, Fabrice; Barbeau, Emmanuel J; Nguyen, Trung; McGonigal, Aileen; Régis, Jean; Chauvel, Patrick; Wendling, Fabrice

    2012-03-01

    The phenomenon of 'déjà vu' is caused by acute disturbance of mnemonic systems of the medial temporal lobe (MTL). In epileptic patients investigated with intracerebral electrodes, déjà vu can be more readily induced by stimulation of the rhinal cortices (RCs) than the hippocampus (H). Whether déjà vu results from acute dysfunction of the familiarity system alone (sustained by RC) or from more extensive involvement of the MTL region (including H) is debatable. We analysed the synchronisation of intracerebral electroencephalography (EEG) signals recorded from RC, H and amygdala (A) in epileptic patients in whom déjà vu was induced by electrical stimulation. EEG signal correlations (between signals from RC, A and H) were evaluated using a nonlinear regression. In comparison with RC stimulations that did not lead to déjà vu (DV-), stimulations triggering déjà vu (DV+) were associated with increased broadband EEG correlation (p=0.01). Changes in correlations were significantly different in the theta band for RC-A (p=0.007) and RC-H (p=0.01) and in the beta band for RC-H (p=0.001) interactions. Déjà vu is associated with increased EEG signal correlation between MTL structures. Results are in favour of a mechanism involving transient co-operation between various MTL structures, not limited to RC alone. Copyright © 2011 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

  18. Critical behavior of the quantum spin- {1}/{2} anisotropic Heisenberg model

    NASA Astrophysics Data System (ADS)

    Sousa, J. Ricardo de

    A two-step renormalization group approach - a decimation followed by an effective field renormalization group (EFRG) - is proposed in this work to study the critical behavior of the quantum spin- {1}/{2} anisotropic Heisenberg model. The new method is illustrated by employing approximations in which clusters with one, two and three spins are used. The values of the critical parameter and critical exponent, in two- and three-dimensional lattices, for the Ising and isotropic Heisenberg limits are calculated and compared with other renormalization group approaches and exact (or series) results.

  19. Full-length genome sequence analysis of an avian leukosis virus subgroup J (ALV-J) as contaminant in live poultry vaccine: The commercial live vaccines might be a potential route for ALV-J transmission.

    PubMed

    Wang, P; Lin, L; Li, H; Shi, M; Gu, Z; Wei, P

    2018-02-25

    One avian leukosis virus subgroup J (ALV-J) strain was isolated from 67 commercial live poultry vaccines produced by various manufacturers during 2013-2016 in China. The complete genomes of the isolate were sequenced and it was found that the genes gag and pol of the strain were relatively conservative, while the gp85 gene of the strain GX14YYA1 had the highest similarities with a field strain GX14ZS14, which was isolated from the chickens of a farm that had once used the same vaccine as the one found to be contaminated with the GX14YYA1. This is the first report of ALV-J contaminant in live poultry vaccine in China. Our finding demonstrates that vaccination of the commercial live vaccines might be a potential new route for ALV-J transmission in chickens and highlights the need for more extensive monitoring of the commercial live vaccines in China. © 2018 Blackwell Verlag GmbH.

  20. Emerging features of ER resident J-proteins in plants

    PubMed Central

    Ohta, Masaru; Takaiwa, Fumio

    2014-01-01

    J-proteins are co-chaperone components of the HSP70 system. J-proteins stimulate Hsp70ATPase activity, which is responsible for stabilizing the interaction of Hsp70 with client proteins. J-proteins are localized in various intracellular compartments including the cytoplasm, mitochondria and endoplasmic reticulum (ER). Five types of ER resident J-proteins (ERdjs) have been found in plants (P58, ERdj2, ERdj2A, ERdj3B and ERdj7). Rice OsERdj3A is located in the vacuole and protein storage vacuoles (PSV, PB-II) under conditions of ER stress. J-proteins that are localized to the vacuole or lysosome are not found in mammals and yeast, suggesting that the presence of OsERdj3A in the vacuole is plant-specific and one of the features unique to plant ERdjs. In this review, we summarize the current state of knowledge and recent research advancements regarding plant ERdjs, and compare mammalian and yeast ERdjs with plant ERdjs. PMID:24614601

  1. FERMI Large Area Telescope Detection of Pulsed γ-Rays from the Vela-Like Pulsars PSR J1048–5832 and PSR J2229+6114

    DOE PAGES

    Abdo, A. A.; Ackermann, M.; Ajello, M.; ...

    2009-11-11

    Within this paper, we report the detection of γ-ray pulsations (≥0.1 GeV) from PSR J2229+6114 and PSR J1048–5832, the latter having been detected as a low-significance pulsar by EGRET. Data in the γ-ray band were acquired by the Large Area Telescope (LAT) aboard the Fermi Gamma-ray Space Telescope, while the radio rotational ephemerides used to fold the γ-ray light curves were obtained using the Green Bank Telescope, the Lovell telescope at Jodrell Bank, and the Parkes Telescope. The two young radio pulsars, located within the error circles of the previously unidentified EGRET sources 3EG J1048–5840 and 3EG J2227+6122, present spin-downmore » characteristics similar to the Vela pulsar. PSR J1048–5832 shows two sharp peaks at phases 0.15 ± 0.01 and 0.57 ± 0.01 relative to the radio pulse confirming the EGRET light curve, while PSR J2229+6114 presents a very broad peak at phase 0.49 ± 0.01. The γ-ray spectra above 0.1 GeV of both pulsars are fit with power laws having exponential cutoffs near 3 GeV, leading to integral photon fluxes of (2.19 ± 0.22 ± 0.32) × 10 –7 cm –2 s –1 for PSR J1048–5832 and (3.77 ± 0.22 ± 0.44) × 10 –7 cm –2 s –1 for PSR J2229+6114. The first uncertainty is statistical and the second is systematic. PSR J1048–5832 is one of the two LAT sources which were entangled together as 3EG J1048–5840. In conclusion, these detections add to the growing number of young γ-ray pulsars that make up the dominant population of GeV γ-ray sources in the Galactic plane.« less

  2. Wallerian degeneration in C57BL/6J and A/J mice: differences in time course of neurofilament and myelin breakdown, macrophage recruitment and iNOS expression

    PubMed Central

    de la Hoz, Cristiane L R; Oliveira, Alexandre L R; de S Queiroz, Luciano; Langone, Francesco

    2003-01-01

    The lower regeneration potential reported for C57BL/6J mice strain after peripheral nerve lesion may result from alterations in crucial events during Wallerian degeneration. We analysed neurofilament and myelin breakdown, macrophage recruitment, NADPH-diaphorase reaction and inducible nitric oxide synthase (iNOS) expression in transected sciatic nerves of C57BL/6J and A/J mice. The neurofilament volume density was lower in C57BL/6J strain mice at 1 and 3 days after lesion, and later equalled the density observed in A/J. C57BL/6J mice presented a high number of cells containing myelin debris, 3 and 5 days after the lesion. In both strains iNOS immunoreactivity was intense in macrophages and less evident in Schwann cells. However, a delay in macrophage recruitment and a lower percentage of iNOS-expressing macrophages on the third day were observed in C57BL/6J mice. NADPH-diaphorase reaction disclosed a similar pattern for both strains until the seventh day. However, at 5 days, cells with slender processes involving ellipsoid segments showed a well-defined cytoplasmic labelling in C57BL/6J whereas in A/J most of these cells exhibited a more granular and disperse labelling. We propose that these differences between A/J and C57BL/6J strains during Wallerian degeneration may be implicated in the lower regeneration potential observed in the latter. PMID:14686692

  3. Optical follow-up of AGL J2251-1239

    NASA Astrophysics Data System (ADS)

    Nesci, Roberto

    2018-01-01

    The AGILE Gamma-ray satellite reported a flaring source (AGL J2251-1239) at RA=342.83, DEC=-12.66 deg. (J2000) in two recent occasions, ATel #11043 (Dec 8, 2017, Lucarelli et al.) and ATel #11127 (Jan 4, 2018, Piano et al.).

  4. jà vu: possible parahippocampal mechanisms.

    PubMed

    Spatt, Josef

    2002-01-01

    jà vu experiences are common in normal subjects. In addition, they are established symptoms of temporal lobe seizures. The author argues that the phenomenon is the result of faulty and isolated activity of a recognition memory system that consists of the parahippocampal gyrus and its neocortical connections. This memory system is responsible for judgments of familiarity. The result is that a momentary perceived scene is given the characteristics of familiarity that normally accompany a conscious recollection. The normal functioning of other brain structures involved in memory retrieval--the prefrontal cortex and the hippocampus proper--leads to the perplexing phenomenological quality of déjà vu. The hypothesis accounts for many characteristics of déjà vu in healthy subjects and is well fitting with experimental findings in patients with epilepsy.

  5. Many Faces of Déjà Vu: a Narrative Review.

    PubMed

    Bošnjak Pašić, Marija; Horvat Velić, Emina; Fotak, Luka; Pašić, Hanna; Srkalović Imširagić, Azijada; Milat, Davorka; Šarac, Helena; Bjedov, Sarah; Petelin GadŽe, Željka

    2018-03-01

    French expression standing for the phrase "already seen" is a déjà vu. It is thought that as much as 97% of the population have experienced déjà vu at least once in their lifetime and 67% experience it regularly. The explanations of this phenomenon in novels and poems include reincarnation, dreams, organic factors, and unconscious memories. In this narrative review connection between déjà vu and various other conditions has been mentioned: false memories, temporal lobe epilepsy and other neurological conditions. In psychiatric patients déjà vu phenomenon is more often seen in patients with anxiety and people with derealisation/ depersonalization. It seems that temporal region is the origin of déjà vu phenomena in both healthy individuals and in individuals with neurological and psychiatric conditions, but the exact mechanism of this phenomenon is however still unknown. More attention should also be given to déjà vu from philosophical and religious perspectives as well. Déjà vu is still an enigma which could only be revealed with multidisciplinary approach through cooperation between neurologists, brain scientists, psychiatrists and experimental psychologists.

  6. Expression and Significance of Cyclophilin J in Primary Gastric Adenocarcinoma.

    PubMed

    Gong, Zhaohua; Mu, Yuling; Chen, Jian; Chu, Hongjin; Lian, Peiwen; Wang, Congcong; Wang, Jiahui; Jiang, Lixin

    2017-08-01

    Biomarkers are essential in early diagnosis and understanding of the molecular mechanism of human cancer. The expression of cyclophilin J, a novel member of the cyclophilin family, was investigated in primary gastric adenocarcinoma. Western blot analysis was carried out on 36 paired tumor and normal tissue samples; immunohistochemical analysis was carried out on 120 gastric carcinoma tissues and normal adjacent tissue. Cyclophilin J protein was overexpressed in 72.2% of gastric carcinoma tissues compared to adjacent normal tissues. Immunohistochemical analysis revealed that cyclophilin J was overexpressed in 49.2% (59/120) and 23.3% (28/120) of gastric carcinoma tissues and adjacent tissues, respectively (p<0.05). Expression of cyclophilin J was associated with the degree of differentiation, but not with lymph node metastasis, gender or depth of tumor infiltration. The overall survival of patients showed no association with the overexpression of cyclophilin J protein. Cyclophilin J expression was up-regulated in gastric carcinoma compared to normal gastric tissues. However, in order to confirm its association with the survival of patients with gastric cancer, more cases need to be studied. Copyright© 2017, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

  7. Absence of social conditioned place preference in BTBR T+tf/J mice: relevance for social motivation testing in rodent models of autism

    PubMed Central

    Pearson, Brandon L.; Bettis, Jaclyn K.; Meyza, Ksenia Z.; Yamamoto, Lace Y.; Blanchard, D. Caroline; Blanchard, Robert J.

    2012-01-01

    A major goal of translation research in autism is to characterize the physiological and psychological processes underlying behavioral abnormalities. Since autism reflects impairments in social motivation, we modified the mouse three-chamber social approach apparatus for use as a social conditioned place preference arena. We paired one of two unique contexts with social interactions in juvenile mice for five or ten conditioning sessions in BTBR T+tf/J mice and a control strain with normal approach behaviors (C57BL/6J) since the BTBR T+tf/J inbred mouse strain displays a variety of behavioral alterations analogous to symptoms of autism spectrum disorders. While C57BL/6J mice formed a conditioned place preference to the context associated with social interactions, particularly those receiving ten days of conditioning, BTBR T+tf/J mice did not. Neither absence of social proximity nor avoidance due to high rates of autogrooming appeared to underlie the impaired positive incentive value of the unconditioned social stimulus in the BTBR T+tf/J strain. These data contribute to a growing body of evidence suggesting that the BTBR T+tf/J strain shows impairments in all diagnostic domains of autism including social motivation. Additionally, social conditioning testing might provide an important social motivation measure in other rodent models of neuropsychiatric disorders characterized by social abnormalities. PMID:22562042

  8. Measurement of C P violation in B → J/ ψ KS0 decays at LHCb

    NASA Astrophysics Data System (ADS)

    Meier, F.; LHCb Collaboration

    2016-07-01

    Analysing a data sample corresponding to an integrated luminosity of 3 fb-1 of pp collisions collected by the LHCb detector at the LHC CP violation in B0→J/ψK0S and B0s→J/ψK0S is measured. The results S(B0→J/ψK0S) = -0.038 ± 0.035 {(stat)} ± 0.020 {(syst)} are consistent with the current world averages and with the Standard Model expectations. In B0s→J/ψK0s the results A_{ΔΓ(B0s→J/ψK0s) = 0.49 ±^{0.77}_{0.65} {(stat)} ± 0.06 {(syst)}, S(B0s→J/ψK0s) = -0.08 ± 0.40 {(stat)} ± 0.08 {(syst)}, C(B0s→J/ψK0s) = - 0.28 ± 0.41 {(stat)} ± 0.08 {(syst)} reflect the first determination of these C P observables paving a new way towards the control of penguin pollutions in the determination of sin 2β.

  9. Radio Detection of LAT PSRs J1741-2054 and J2032+4127: No Longer Just Gamma-Ray Pulsars

    DOE PAGES

    Camilo, F.; Ray, P. S.; Ransom, S. M.; ...

    2009-10-07

    We present that sixteen pulsars have been discovered so far in blind searches of photons collected with the Large Area Telescope on the Fermi Gamma-ray Space Telescope. We here report the discovery of radio pulsations from two of them. PSR J1741-2054, with period P = 413 ms, was detected in archival Parkes telescope data and subsequently has been detected at the Green Bank Telescope (GBT). Its received flux varies greatly due to interstellar scintillation and it has a very small dispersion measure of DM = 4.7 pc cm –3, implying a distance of ≈0.4 kpc and possibly the smallest luminosity of any known radio pulsar. At this distance, for isotropic emission, its gamma-ray luminosity above 0.1 GeV corresponds to 28% of the spin-down luminosity ofmore » $$\\dot{E} = 9.4\\times 10^{33}$$ erg s–1. The gamma-ray profile occupies 1/3 of pulse phase and has three closely spaced peaks with the first peak lagging the radio pulse by δ = 0.29 P. We have also identified a soft Swift source that is the likely X-ray counterpart. In many respects PSR J1741-2054 resembles the Geminga pulsar. The second source, PSR J2032+4127, was detected at the GBT. It has P = 143 ms, and its DM = 115 pc cm –3 suggests a distance of ≈3.6 kpc, but we consider it likely that it is located within the Cyg OB2 stellar association at half that distance. The radio emission is nearly 100% linearly polarized, and the main radio peak precedes by δ = 0.15 P the first of two narrow gamma-ray peaks that are separated by Δ = 0.50 P. The second peak has a harder spectrum than the first one, following a trend observed in young gamma-ray pulsars. Faint, diffuse X-ray emission in a Chandra image is possibly its pulsar wind nebula. Finally, the wind of PSR J2032+4127 is responsible for the formerly unidentified HEGRA source TeV J2032+4130. PSR J2032+4127 is coincident in projection with MT91 213, a Be star in Cyg OB2, although apparently not a binary companion of it.« less

  10. Search for hc→π+π-J /ψ via ψ (3686 )→π0π+π-J

    NASA Astrophysics Data System (ADS)

    Ablikim, M.; Achasov, M. N.; Ahmed, S.; Ai, X. C.; Albrecht, M.; Ambrose, D. J.; Amoroso, A.; An, F. F.; An, Q.; Bai, J. Z.; Bakina, O.; Ferroli, R. Baldini; Ban, Y.; Bennett, D. W.; Bennett, J. V.; Berger, N.; Bertani, M.; Bettoni, D.; Bian, J. M.; Bianchi, F.; Boger, E.; Boyko, I.; Briere, R. A.; Cai, H.; Cai, X.; Cakir, O.; Calcaterra, A.; Cao, G. F.; Cetin, S. A.; Chai, J.; Chang, J. F.; Chelkov, G.; Chen, G.; Chen, H. S.; Chen, J. C.; Chen, M. L.; Chen, P. L.; Chen, S. J.; Chen, X. R.; Chen, Y. B.; Chu, X. K.; Cibinetto, G.; Dai, H. L.; Dai, J. P.; Dbeyssi, A.; Dedovich, D.; Deng, Z. Y.; Denig, A.; Denysenko, I.; Destefanis, M.; de Mori, F.; Ding, Y.; Dong, C.; Dong, J.; Dong, L. Y.; Dong, M. Y.; Dou, Z. L.; Du, S. X.; Duan, P. F.; Fang, J.; Fang, S. S.; Fang, Y.; Farinelli, R.; Fava, L.; Fegan, S.; Feldbauer, F.; Felici, G.; Feng, C. Q.; Fioravanti, E.; Fritsch, M.; Fu, C. D.; Gao, Q.; Gao, X. L.; Gao, Y.; Gao, Z.; Garzia, I.; Goetzen, K.; Gong, L.; Gong, W. X.; Gradl, W.; Greco, M.; Gu, M. H.; Gu, Y. T.; Guo, A. Q.; Guo, R. P.; Guo, Y. P.; Haddadi, Z.; Han, S.; Hao, X. Q.; Harris, F. A.; He, K. L.; He, X. Q.; Heinsius, F. H.; Held, T.; Heng, Y. K.; Holtmann, T.; Hou, Z. L.; Hu, H. M.; Hu, T.; Hu, Y.; Huang, G. S.; Huang, J. S.; Huang, X. T.; Huang, X. Z.; Huang, Z. L.; Hussain, T.; Andersson, W. Ikegami; Ji, Q.; Ji, Q. P.; Ji, X. B.; Ji, X. L.; Jiang, L. W.; Jiang, X. S.; Jiang, X. Y.; Jiao, J. B.; Jiao, Z.; Jie, Q. L.; Jin, D. P.; Jin, S.; Johansson, T.; Julin, A.; Kalantar-Nayestanaki, N.; Kang, X. L.; Kang, X. S.; Kavatsyuk, M.; Ke, B. C.; Kiese, P.; Kliemt, R.; Kloss, B.; Kolcu, O. B.; Kopf, B.; Kornicer, M.; Kupsc, A.; Kühn, W.; Lange, J. S.; Lara, M.; Larin, P.; Lavezzi, L.; Leithoff, H.; Leng, C.; Li, C.; Li, Cheng; Li, D. M.; Li, F.; Li, F. Y.; Li, G.; Li, H. B.; Li, H. J.; Li, J. C.; Li, Jin; Li, Kang; Li, Ke; Li, Lei; Li, P. L.; Li, P. R.; Li, Q. Y.; Li, W. D.; Li, W. G.; Li, X. L.; Li, X. N.; Li, X. Q.; Li, Z. B.; Liang, H.; Liang, Y. F.; Liang, Y. T.; Liao, G. R.; Lin, D. X.; Liu, B.; Liu, B. J.; Liu, C. X.; Liu, D.; Liu, F. H.; Liu, Fang; Liu, Feng; Liu, H. B.; Liu, H. M.; Liu, Huanhuan; Liu, Huihui; Liu, J. B.; Liu, J. P.; Liu, J. Y.; Liu, K.; Liu, K. Y.; Liu, L. D.; Liu, P. L.; Liu, Q.; Liu, S. B.; Liu, X.; Liu, Y. B.; Liu, Z. A.; Liu, Zhiqing; Loehner, H.; Long, Y. F.; Lou, X. C.; Lu, H. J.; Lu, J. G.; Lu, Y.; Lu, Y. P.; Luo, C. L.; Luo, M. X.; Luo, T.; Luo, X. L.; Lyu, X. R.; Ma, F. C.; Ma, H. L.; Ma, L. L.; Ma, M. M.; Ma, Q. M.; Ma, T.; Ma, X. N.; Ma, X. Y.; Ma, Y. M.; Maas, F. E.; Maggiora, M.; Malik, Q. A.; Mao, Y. J.; Mao, Z. P.; Marcello, S.; Messchendorp, J. G.; Mezzadri, G.; Min, J.; Min, T. J.; Mitchell, R. E.; Mo, X. H.; Mo, Y. J.; Morales, C. Morales; Muchnoi, N. Yu.; Muramatsu, H.; Musiol, P.; Nefedov, Y.; Nerling, F.; Nikolaev, I. B.; Ning, Z.; Nisar, S.; Niu, S. L.; Niu, X. Y.; Olsen, S. L.; Ouyang, Q.; Pacetti, S.; Pan, Y.; Papenbrock, M.; Patteri, P.; Pelizaeus, M.; Peng, H. P.; Peters, K.; Pettersson, J.; Ping, J. L.; Ping, R. G.; Poling, R.; Prasad, V.; Qi, H. R.; Qi, M.; Qian, S.; Qiao, C. F.; Qin, J. J.; Qin, N.; Qin, X. S.; Qin, Z. H.; Qiu, J. F.; Rashid, K. H.; Redmer, C. F.; Ripka, M.; Rong, G.; Rosner, Ch.; Sarantsev, A.; Savrié, M.; Schnier, C.; Schoenning, K.; Shan, W.; Shao, M.; Shen, C. P.; Shen, P. X.; Shen, X. Y.; Sheng, H. Y.; Song, J. J.; Song, W. M.; Song, X. Y.; Sosio, S.; Spataro, S.; Sun, G. X.; Sun, J. F.; Sun, S. S.; Sun, X. H.; Sun, Y. J.; Sun, Y. Z.; Sun, Z. J.; Sun, Z. T.; Tang, C. J.; Tang, X.; Tapan, I.; Thorndike, E. H.; Tiemens, M.; Uman, I.; Varner, G. S.; Wang, B.; Wang, B. L.; Wang, D.; Wang, D. Y.; Wang, Dan; Wang, K.; Wang, L. L.; Wang, L. S.; Wang, M.; Wang, P.; Wang, P. L.; Wang, W. P.; Wang, X. F.; Wang, Y.; Wang, Y. D.; Wang, Y. F.; Wang, Y. Q.; Wang, Z.; Wang, Z. G.; Wang, Z. Y.; Wang, Zongyuan; Weber, T.; Wei, D. H.; Weidenkaff, P.; Wen, S. P.; Wiedner, U.; Wolke, M.; Wu, L. H.; Wu, L. J.; Wu, Z.; Xia, L.; Xia, Y.; Xiao, D.; Xiao, H.; Xiao, Z. J.; Xie, Y. G.; Xie, Y. H.; Xiong, X. A.; Xiu, Q. L.; Xu, G. F.; Xu, J. J.; Xu, L.; Xu, Q. J.; Xu, Q. N.; Xu, X. P.; Yan, L.; Yan, W. B.; Yan, Y. H.; Yang, H. J.; Yang, H. X.; Yang, L.; Yang, Y. X.; Ye, M.; Ye, M. H.; Yin, J. H.; You, Z. Y.; Yu, B. X.; Yu, C. X.; Yu, J. S.; Yuan, C. Z.; Yuan, Y.; Yuncu, A.; Zafar, A. A.; Zeng, Y.; Zeng, Z.; Zhang, B. X.; Zhang, B. Y.; Zhang, C. C.; Zhang, D. H.; Zhang, H. H.; Zhang, H. Y.; Zhang, J.; Zhang, J. L.; Zhang, J. Q.; Zhang, J. W.; Zhang, J. Y.; Zhang, J. Z.; Zhang, K.; Zhang, S. Q.; Zhang, X. Y.; Zhang, Y. H.; Zhang, Y. T.; Zhang, Yang; Zhang, Yao; Zhang, Yu; Zhang, Z. H.; Zhang, Z. P.; Zhang, Z. Y.; Zhao, G.; Zhao, J. W.; Zhao, J. Y.; Zhao, J. Z.; Zhao, Lei; Zhao, Ling; Zhao, M. G.; Zhao, Q.; Zhao, S. J.; Zhao, T. C.; Zhao, Y. B.; Zhao, Z. G.; Zhemchugov, A.; Zheng, B.; Zheng, J. P.; Zheng, Y. H.; Zhong, B.; Zhou, L.; Zhou, X.; Zhou, X. K.; Zhou, X. R.; Zhou, X. Y.; Zhu, J.; Zhu, K.; Zhu, K. J.; Zhu, S.; Zhu, S. H.; Zhu, X. L.; Zhu, Y. C.; Zhu, Y. S.; Zhu, Z. A.; Zhuang, J.; Zotti, L.; Zou, B. S.; Zou, J. H.; Besiii Collaboration

    2018-03-01

    Using a data sample of 448.1 ×106 ψ (3686 ) events collected with the BESIII detector operating at the BEPCII, we perform search for the hadronic transition hc→π+π-J /ψ via ψ (3686 )→π0hc. No signals of the transition are observed, and the upper limit on the product branching fraction B (ψ (3686 )→π0hc)B (hc→π+π-J /ψ ) at the 90% confidence level (C.L.) is determined to be 2.0 ×10-6. This is the most stringent upper limit to date.

  11. Performance of J-33-A-21 and J-33-A-23 Compressors with and without Water Injection

    NASA Technical Reports Server (NTRS)

    Beede, William L.

    1948-01-01

    In an investigation of the J-33-A-21 and the J-33-A-23 compressors with and without water injection, it was discovered that the compressors reacted differently to water injection although they were physically similar. An analysis of the effect of water injection on compressor performance and the consequent effect on matching of the compressor and turbine components in the turbojet engine was made. The analysis of component matching is based on a turbine flow function defined as the product of the equivalent weight flow and the reciprocal of the compressor pressure ratio.

  12. RXTE PCA Detection of a New Outburst of XTE J1728-295 (probably IGR J17285-2922)

    NASA Astrophysics Data System (ADS)

    Markwardt, Craig B.; Swank, Jean H.

    2010-08-01

    We report the detection of a new outburst of a source designated XTE J1728-295 in the RXTE PCA scans, which is probably the same as IGR J17285-2922. This source was first detected in August-October 2003 with PCA scans of the galactic center region, and is speculated to be a black hole candidate (Barlow et al. 2005, A&A, 437, L27). In PCA scans on 2010-08-28 near 09:35 UTC, the source rose to a flux of 6.5 mCrab (2-10 keV).

  13. The three-dimensional model for helical columns on type-J synchronous counter-current chromatography.

    PubMed

    Guan, Y H; van den Heuvel, Remco

    2011-08-05

    Unlike the existing 2-D pseudo-ring model for helical columns undergoing synchronous type-J planetary motion of counter-current chromatograph (CCC), the 3-D "helix" model developed in this work shows that there is a second normal force (i.e. the binormal force) applied virtually in the axial direction of the helical column. This force alternates in the two opposite directions and intensifies phase mixing with increasing the helix angle. On the contrary, the 2-D spiral column operated on the same CCC device lacks this third-dimensional mixing force. The (principal) normal force quantified by this "helix" model has been the same as that by the pseudo-ring model. With β>0.25, this normal centrifugal force has been one-directional and fluctuates cyclically. Different to the spiral column, this "helix" model shows that the centrifugal force (i.e. the hydrostatic force) does not contribute to stationary phase retention in the helical column. Between the popular helical columns and the emerging spiral columns for type-J synchronous CCC, this work has thus illustrated that the former is associated with better phase mixing yet poor retention for the stationary phase whereas the latter has potential for better retention for the stationary phase yet poor phase mixing. The methodology developed in this work may be regarded as a new platform for designing optimised CCC columns for analytical and engineering applications. Copyright © 2011 Elsevier B.V. All rights reserved.

  14. AN IMPROVED DYNAMICAL MODEL FOR THE MICROQUASAR XTE J1550-564

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Orosz, Jerome A.; Steiner, James F.; McClintock, Jeffrey E.

    2011-04-01

    We present an improved dynamical model of the X-ray binary and microquasar XTE J1550-564 based on new moderate-resolution optical spectroscopy and near-infrared photometry obtained with the 6.5 m Magellan Telescopes at Las Campanas Observatory. Twelve spectra of the source were obtained using the Magellan Echellette Spectrograph between 2008 May 6 and August 4. In addition, several hundred images of the field were obtained between 2006 May and 2009 July in the J and K{sub S} filters using the PANIC camera. The agreement between the 2006/2007 and 2008 J and K{sub S} light curves is not perfect, and the differences canmore » plausibly be attributed to a hot spot on the accretion disk during the 2006/2007 observations. By combining our new radial velocity measurements with previous measurements obtained in 2001 May at the 8.2 m Very Large Telescope and with light curves, we find an orbital period of P = 1.5420333 {+-} 0.0000024 days and a radial velocity semiamplitude of K{sub 2} = 363.14 {+-} 5.97 km s{sup -1}, which together imply an optical mass function of f(M) = 7.65 {+-} 0.38 M{sub sun}. We find that the projected rotational velocity of the secondary star is 55 {+-} 5 km s{sup -1}, which implies a very extreme mass ratio of Q {identical_to} M/M{sub 2} {approx} 30. Using a model of a Roche lobe-filling star and an azimuthally symmetric accretion disk, we fit simultaneously optical light curves from 2001, near-infrared light curves from 2008, and all of the radial velocity measurements to derive system parameters. We find an inclination of 74.{sup 0}7 {+-} 3.{sup 0}8 and component masses of M{sub 2} = 0.30 {+-} 0.07 M{sub sun} and M = 9.10 {+-} 0.61 M{sub sun} for the secondary star and black hole, respectively. We note that these results depend on the assumption that in 2008, the disk did not have a hot spot, and that the fraction of light contributed by the accretion disk did not change between the spectroscopic and photometric observations. By considering two

  15. 40 CFR Appendix J to Part 75... - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 16 2011-07-01 2011-07-01 false [Reserved] J Appendix J to Part 75-Compliance Dates for Revised Recordkeeping Requirements and Missing Data Procedures Protection of Environment... to Part 75—Compliance Dates for Revised Recordkeeping Requirements and Missing Data Procedures...

  16. 40 CFR Appendix J to Part 75... - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false [Reserved] J Appendix J to Part 75-Compliance Dates for Revised Recordkeeping Requirements and Missing Data Procedures Protection of Environment... to Part 75—Compliance Dates for Revised Recordkeeping Requirements and Missing Data Procedures...

  17. 40 CFR Appendix J to Part 75... - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 17 2012-07-01 2012-07-01 false [Reserved] J Appendix J to Part 75-Compliance Dates for Revised Recordkeeping Requirements and Missing Data Procedures Protection of Environment... to Part 75—Compliance Dates for Revised Recordkeeping Requirements and Missing Data Procedures...

  18. 40 CFR Appendix J to Part 75... - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 17 2014-07-01 2014-07-01 false [Reserved] J Appendix J to Part 75-Compliance Dates for Revised Recordkeeping Requirements and Missing Data Procedures Protection of Environment... to Part 75—Compliance Dates for Revised Recordkeeping Requirements and Missing Data Procedures...

  19. 40 CFR Appendix J to Part 75... - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 17 2013-07-01 2013-07-01 false [Reserved] J Appendix J to Part 75-Compliance Dates for Revised Recordkeeping Requirements and Missing Data Procedures Protection of Environment... to Part 75—Compliance Dates for Revised Recordkeeping Requirements and Missing Data Procedures...

  20. 32 CFR Appendix J to Part 275 - Format for Customer Authorization

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Format for Customer Authorization J Appendix J... OF 1978 Pt. 275, App. J Appendix J to Part 275—Format for Customer Authorization Pursuant to section 3404(a) of the Right to Financial Privacy Act of 1978, I, [Name of customer], having read the...

  1. Structural insights into translational recoding by frameshift suppressor tRNA SufJ

    DOE PAGES

    Fagan, Crystal E.; Maehigashi, Tatsuya; Dunkle, Jack A.; ...

    2014-10-28

    The three-nucleotide mRNA reading frame is tightly regulated during translation to ensure accurate protein expression. Translation errors that lead to aberrant protein production can result from the uncoupled movement of the tRNA in either the 5' or 3' direction on mRNA. Here, we report the biochemical and structural characterization of +1 frameshift suppressor tRNA SufJ, a tRNA known to decode four, instead of three, nucleotides. Frameshift suppressor tRNA SufJ contains an insertion 5' to its anticodon, expanding the anticodon loop from seven to eight nucleotides. Our results indicate that the expansion of the anticodon loop of either ASL SufJ ormore » tRNA SufJ does not affect its affinity for the A site of the ribosome. Structural analyses of both ASL SufJ and ASL Thr bound to the Thermus thermophilus 70S ribosome demonstrate both ASLs decode in the zero frame. Although the anticodon loop residues 34–37 are superimposable with canonical seven-nucleotide ASLs, the single C31.5 insertion between nucleotides 31 and 32 in ASL SufJ imposes a conformational change of the anticodon stem, that repositions and tilts the ASL toward the back of the A site. Further modeling analyses reveal that this tilting would cause a distortion in full-length A-site tRNA SufJ during tRNA selection and possibly impede gripping of the anticodon stem by 16S rRNA nucleotides in the P site. Together, these data implicate tRNA distortion as a major driver of noncanonical translation events such as frameshifting.« less

  2. The CO-12 and CO-13 J=2-1 and J=1-0 observations of hot and cold galaxies

    NASA Technical Reports Server (NTRS)

    Xie, Shuding; Schloerb, F. Peter; Young, Judith

    1990-01-01

    Researchers observed the nuclear regions of the galaxies NGC 2146 and IC 342 in CO-12 and CO-13 J=1-0 and J=2-1 lines using the Five College Radio Astronomy Observatory (FCRAO) 14m telescope. NGC 2146 is a peculiar Sab spiral galaxy. Its complex optical morphology and strong nuclear radio continuum emission suggest that it is experiencing a phase of violent activity and could have a polar ring which may have resulted from an interaction. IC 342 is a nearby luminous Scd spiral galaxy. Strong CO, infrared and radio continuum emission from the nuclear region of IC 342 indicate enhanced star-forming activity, and interferometric CO-12 J=1-0 observations reveal a bar-like structure centered on the nucleus, along the dark lane in the NS direction. These two galaxies are selected based on their different dust temperatures and star formation efficiencies (SFE) as derived from the Infrared Astronomy Satellite (IRAS) S sub 60 mu/S sub 100 mu flux density ratio and L sub IR/M(H2), respectively, with a relatively high SFE and dust temperature of 45 K in NGC 2146 and a relatively low SFE and dust temperature of 35 K in IC 342. The data from the different CO-12 and CO-13 lines are used to study the physical conditions in the molecular clouds in the galaxies. Researchers also consider the radiative transfer to determine whether a warm and optically thin gas component exists in these galaxies, as has been suggested in the case of M82 (Knapp et al. 1980), and whether the warm gas is related to the dust properties. Since optically thin CO-12 gas is rarely detected in our own Galaxy (except in outflow sources), to confirm its existence in external galaxies is very important in understanding the molecular content of external galaxies and its relationship to star formation activity. The present CO-12 J=2-1 and CO-13 J=2-1 and J=1-0 data for NGC 2146 are the first detections of this galaxy to our knowledge. The CO-12 J=1-0 distribution in NGC 2146 has been measured as part of the FCRAO

  3. Rapid measurement of 3J(H N-H alpha) and 3J(N-H beta) coupling constants in polypeptides.

    PubMed

    Barnwal, Ravi Pratap; Rout, Ashok K; Chary, Kandala V R; Atreya, Hanudatta S

    2007-12-01

    We present two NMR experiments, (3,2)D HNHA and (3,2)D HNHB, for rapid and accurate measurement of 3J(H N-H alpha) and 3J(N-H beta) coupling constants in polypeptides based on the principle of G-matrix Fourier transform NMR spectroscopy and quantitative J-correlation. These experiments, which facilitate fast acquisition of three-dimensional data with high spectral/digital resolution and chemical shift dispersion, will provide renewed opportunities to utilize them for sequence specific resonance assignments, estimation/characterization of secondary structure with/without prior knowledge of resonance assignments, stereospecific assignment of prochiral groups and 3D structure determination, refinement and validation. Taken together, these experiments have a wide range of applications from structural genomics projects to studying structure and folding in polypeptides.

  4. Optical spectroscopic followup of XMMSL1 J164303.7+653253 in the error box of IGR J16426+6536

    NASA Astrophysics Data System (ADS)

    Parisi, P.; Masetti, N.; Malizia, A.; Morelli, L.; Mason, E.; Dean, A. J.; Ubertini, P.

    2008-10-01

    We report on a spectroscopic observation of the optical object USNO-A2.0 1500-06133361 (with J2000 coordinates RA = 16 43 04.07, Dec = +65 32 50.9 and magnitude R ~ 18.9) inside the error circle of the XMM-Newton slew source XMMLS1 J164303.7+653253 (see Ibarra et al., ATel #1397), possibly associated with the unidentified INTEGRAL source IGR J16426+6536 (Bird et al. 2007, ApJS, 170, 175). The observations were performed on 2008 February 04, starting at 06:10 UT, with DOLORES, a focal reducer instrument installed on the 3.58m Telescopio Nazionale Galileo (TNG) in the Astronomical Observatory of Roque de Los Muchachos (Santa Cruz de La Palma, Spain), for a total exposure time of 1800 s.

  5. 29 CFR 102.94 - Expeditious processing of section 10(j) cases.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 2 2010-07-01 2010-07-01 false Expeditious processing of section 10(j) cases. 102.94..., SERIES 8 Procedure in Cases Under Section 10(j), (l), and (m) of the Act § 102.94 Expeditious processing of section 10(j) cases. (a) Whenever temporary relief or a restraining order pursuant to section 10(j...

  6. Thermal properties of spin-S Kitaev-Heisenberg model on a honeycomb lattice

    NASA Astrophysics Data System (ADS)

    Suzuki, Takafumi; Yamaji, Youhei

    2018-05-01

    Temperature (T) dependence of heat capacity C (T) in the S = 1 / 2 Kitaev honeycomb model shows a double-peak structure resulting from fractionalization of spins into two kinds of Majorana fermions. Recently it has been discussed that the double-peak structure in C (T) is also observed in magnetic ordered phases of the S = 1 / 2 Kitaev-Heisenberg (KH) model on a honeycomb lattice when the system is located in the vicinity of the Kitaev's spin liquid phase. In addition to the S = 1 / 2 spin case, similar double-peak structure has been confirmed in the KH honeycomb model for classical Heisenberg spins, where spin S is regarded as S → ∞ . We investigate spin-S dependence of C (T) for the KH honeycomb models by using thermal pure quantum state. We also perform classical Monte Carlo calculations to obtain C (T) for the classical KH model. From obtained results, we find that the origin of the high-temperature peak is different between the quantum spin case with small Ss and the classical Heisenberg spin case. Furthermore, the high-temperature peak in the quantum spin case, which is one of the clues for fractionalization of spins, disappears for S > 1 .

  7. Dynamics of a quantum spin liquid beyond integrability: The Kitaev-Heisenbergmodel in an augmented parton mean-field theory

    NASA Astrophysics Data System (ADS)

    Knolle, Johannes; Bhattacharjee, Subhro; Moessner, Roderich

    2018-04-01

    We present an augmented parton mean-field theory which (i) reproduces the exact ground state, spectrum, and dynamics of the quantum spin-liquid phase of Kitaev's honeycomb model, and (ii) is amenable to the inclusion of integrability breaking terms, allowing a perturbation theory from a controlled starting point. Thus, we exemplarily study dynamical spin correlations of the honeycomb Kitaev quantum spin liquid within the K -Jmodel, which includes Heisenberg and symmetric-anisotropic (pseudodipolar) interactions. This allows us to trace changes of the correlations in the regime of slowly moving fluxes, where the theory captures the dominant deviations when integrability is lost. These include an asymmetric shift together with a broadening of the dominant peak in the response as a function of frequency, the generation of further-neighbor correlations and their structure in real and spin space, and a resulting loss of an approximate rotational symmetry of the structure factor in reciprocal space. We discuss the limitations of this approach and also view the neutron-scattering experiments on the putative proximate quantum spin-liquid material α -RuCl3 in the light of the results from this extended parton theory.

  8. Design modeling of the 100-J diode-pumped solid-state laser for Project Mercury

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Orth, C., LLNL

    We present the energy, propagation, and thermal modeling for a diode-pumped solid-state laser called Mercury being designed and built at LLNL using Yb:S-FAP [i.e., Yb{sup 3+}-doped Sr{sub 5}(PO{sub 4}){sub 3}F crystals] for the gain medium. This laser is intended to produce 100 J pulses at 1 to 10 ns at 10 Hz with an electrical efficiency of {approximately}10%. Our modeling indicates that the laser will be able to meet its performance goals.

  9. Lung tumor production and tissue metal distribution after exposure to manual metal ARC-stainless steel welding fume in A/J and C57BL/6J mice.

    PubMed

    Zeidler-Erdely, Patti C; Battelli, Lori A; Salmen-Muniz, Rebecca; Li, Zheng; Erdely, Aaron; Kashon, Michael L; Simeonova, Petia P; Antonini, James M

    2011-01-01

    Stainless steel welding produces fumes that contain carcinogenic metals. Therefore, welders may be at risk for the development of lung cancer, but animal data are inadequate in this regard. Our main objective was to examine lung tumor production and histopathological alterations in lung-tumor-susceptible (A/J) and -resistant C57BL/6J (B6) mice exposed to manual metal arc-stainless steel (MMA-SS) welding fume. Male mice were exposed to vehicle or MMA-SS welding fume (20 mg/kg) by pharyngeal aspiration once per month for 4 mo. At 78 wk postexposure, gross tumor counts and histopathological changes were assessed and metal analysis was done on extrapulmonary tissue (aorta, heart, kidney, and liver). At 78 wk postexposure, gross lung tumor multiplicity and incidence were unremarkable in mice exposed to MMA-SS welding fume. Histopathology revealed that only the exposed A/J mice contained minimal amounts of MMA-SS welding fume in the lung and statistically increased lymphoid infiltrates and alveolar macrophages. A significant increase in tumor multiplicity in the A/J strain was observed at 78 wk. Metal analysis of extrapulmonary tissue showed that only the MMA-SS-exposed A/J mice had elevated levels of Cr, Cu, Mn, and Zn in kidney and Cr in liver. In conclusion, this study further supports that MMA-SS welding fume does not produce a significant tumorigenic response in an animal model, but may induce a chronic lung immune response. In addition, long-term extrapulmonary tissue alterations in metals in the susceptible A/J mouse suggest that the adverse effects of this fume might be cumulative.

  10. Evidence for Exotic Hadron Contributions to Λ_{b}^{0}→J/ψpπ^{-} Decays.

    PubMed

    Aaij, R; Abellán Beteta, C; Adeva, B; Adinolfi, M; Ajaltouni, Z; Akar, S; Albrecht, J; Alessio, F; Alexander, M; Ali, S; Alkhazov, G; Alvarez Cartelle, P; Alves, A A; Amato, S; Amerio, S; Amhis, Y; An, L; Anderlini, L; Andreassi, G; Andreotti, M; Andrews, J E; Appleby, R B; Aquines Gutierrez, O; Archilli, F; d'Argent, P; Arnau Romeu, J; Artamonov, A; Artuso, M; Aslanides, E; Auriemma, G; Baalouch, M; Bachmann, S; Back, J J; Badalov, A; Baesso, C; Baldini, W; Barlow, R J; Barschel, C; Barsuk, S; Barter, W; Batozskaya, V; Battista, V; Bay, A; Beaucourt, L; Beddow, J; Bedeschi, F; Bediaga, I; Bel, L J; Bellee, V; Belloli, N; Belous, K; Belyaev, I; Ben-Haim, E; Bencivenni, G; Benson, S; Benton, J; Berezhnoy, A; Bernet, R; Bertolin, A; Bettler, M-O; van Beuzekom, M; Bifani, S; Billoir, P; Bird, T; Birnkraut, A; Bitadze, A; Bizzeti, A; Blake, T; Blanc, F; Blouw, J; Blusk, S; Bocci, V; Boettcher, T; Bondar, A; Bondar, N; Bonivento, W; Borghi, S; Borisyak, M; Borsato, M; Bossu, F; Boubdir, M; Bowcock, T J V; Bowen, E; Bozzi, C; Braun, S; Britsch, M; Britton, T; Brodzicka, J; Buchanan, E; Burr, C; Bursche, A; Buytaert, J; Cadeddu, S; Calabrese, R; Calvi, M; Calvo Gomez, M; Campana, P; Campora Perez, D; Capriotti, L; Carbone, A; Carboni, G; Cardinale, R; Cardini, A; Carniti, P; Carson, L; Carvalho Akiba, K; Casse, G; Cassina, L; Castillo Garcia, L; Cattaneo, M; Cauet, Ch; Cavallero, G; Cenci, R; Charles, M; Charpentier, Ph; Chatzikonstantinidis, G; Chefdeville, M; Chen, S; Cheung, S-F; Chobanova, V; Chrzaszcz, M; Cid Vidal, X; Ciezarek, G; Clarke, P E L; Clemencic, M; Cliff, H V; Closier, J; Coco, V; Cogan, J; Cogneras, E; Cogoni, V; Cojocariu, L; Collazuol, G; Collins, P; Comerma-Montells, A; Contu, A; Cook, A; Coquereau, S; Corti, G; Corvo, M; Costa Sobral, C M; Couturier, B; Cowan, G A; Craik, D C; Crocombe, A; Cruz Torres, M; Cunliffe, S; Currie, R; D'Ambrosio, C; Dall'Occo, E; Dalseno, J; David, P N Y; Davis, A; De Aguiar Francisco, O; De Bruyn, K; De Capua, S; De Cian, M; De Miranda, J M; De Paula, L; De Simone, P; Dean, C-T; Decamp, D; Deckenhoff, M; Del Buono, L; Demmer, M; Derkach, D; Deschamps, O; Dettori, F; Dey, B; Di Canto, A; Dijkstra, H; Dordei, F; Dorigo, M; Dosil Suárez, A; Dovbnya, A; Dreimanis, K; Dufour, L; Dujany, G; Dungs, K; Durante, P; Dzhelyadin, R; Dziurda, A; Dzyuba, A; Déléage, N; Easo, S; Egede, U; Egorychev, V; Eidelman, S; Eisenhardt, S; Eitschberger, U; Ekelhof, R; Eklund, L; Elsasser, Ch; Ely, S; Esen, S; Evans, H M; Evans, T; Falabella, A; Farley, N; Farry, S; Fay, R; Ferguson, D; Fernandez Albor, V; Ferrari, F; Ferreira Rodrigues, F; Ferro-Luzzi, M; Filippov, S; Fiore, M; Fiorini, M; Firlej, M; Fitzpatrick, C; Fiutowski, T; Fleuret, F; Fohl, K; Fontana, M; Fontanelli, F; Forshaw, D C; Forty, R; Frank, M; Frei, C; Frosini, M; Fu, J; Furfaro, E; Färber, C; Gallas Torreira, A; Galli, D; Gallorini, S; Gambetta, S; Gandelman, M; Gandini, P; Gao, Y; García Pardiñas, J; Garra Tico, J; Garrido, L; Garsed, P J; Gascon, D; Gaspar, C; Gavardi, L; Gazzoni, G; Gerick, D; Gersabeck, E; Gersabeck, M; Gershon, T; Ghez, Ph; Gianì, S; Gibson, V; Girard, O G; Giubega, L; Gizdov, K; Gligorov, V V; Golubkov, D; Golutvin, A; Gomes, A; Gorelov, I V; Gotti, C; Grabalosa Gándara, M; Graciani Diaz, R; Granado Cardoso, L A; Graugés, E; Graverini, E; Graziani, G; Grecu, A; Griffith, P; Grillo, L; Gruberg Cazon, B R; Grünberg, O; Gushchin, E; Guz, Yu; Gys, T; Göbel, C; Hadavizadeh, T; Hadjivasiliou, C; Haefeli, G; Haen, C; Haines, S C; Hall, S; Hamilton, B; Han, X; Hansmann-Menzemer, S; Harnew, N; Harnew, S T; Harrison, J; He, J; Head, T; Heister, A; Hennessy, K; Henrard, P; Henry, L; Hernando Morata, J A; van Herwijnen, E; Heß, M; Hicheur, A; Hill, D; Hombach, C; Hulsbergen, W; Humair, T; Hushchyn, M; Hussain, N; Hutchcroft, D; Idzik, M; Ilten, P; Jacobsson, R; Jaeger, A; Jalocha, J; Jans, E; Jawahery, A; John, M; Johnson, D; Jones, C R; Joram, C; Jost, B; Jurik, N; Kandybei, S; Kanso, W; Karacson, M; Kariuki, J M; Karodia, S; Kecke, M; Kelsey, M; Kenyon, I R; Kenzie, M; Ketel, T; Khairullin, E; Khanji, B; Khurewathanakul, C; Kirn, T; Klaver, S; Klimaszewski, K; Koliiev, S; Kolpin, M; Komarov, I; Koopman, R F; Koppenburg, P; Kozachuk, A; Kozeiha, M; Kravchuk, L; Kreplin, K; Kreps, M; Krokovny, P; Kruse, F; Krzemien, W; Kucewicz, W; Kucharczyk, M; Kudryavtsev, V; Kuonen, A K; Kurek, K; Kvaratskheliya, T; Lacarrere, D; Lafferty, G; Lai, A; Lambert, D; Lanfranchi, G; Langenbruch, C; Langhans, B; Latham, T; Lazzeroni, C; Le Gac, R; van Leerdam, J; Lees, J-P; Leflat, A; Lefrançois, J; Lefèvre, R; Lemaitre, F; Lemos Cid, E; Leroy, O; Lesiak, T; Leverington, B; Li, Y; Likhomanenko, T; Lindner, R; Linn, C; Lionetto, F; Liu, B; Liu, X; Loh, D; Longstaff, I; Lopes, J H; Lucchesi, D; Lucio Martinez, M; Luo, H; Lupato, A; Luppi, E; Lupton, O; Lusiani, A; Lyu, X; Machefert, F; Maciuc, F; Maev, O; Maguire, K; Malde, S; Malinin, A; Maltsev, T; Manca, G; Mancinelli, G; Manning, P; Maratas, J; Marchand, J F; Marconi, U; Marin Benito, C; Marino, P; Marks, J; Martellotti, G; Martin, M; Martinelli, M; Martinez Santos, D; Martinez Vidal, F; Martins Tostes, D; Massacrier, L M; Massafferri, A; Matev, R; Mathad, A; Mathe, Z; Matteuzzi, C; Mauri, A; Maurin, B; Mazurov, A; McCann, M; McCarthy, J; McNab, A; McNulty, R; Meadows, B; Meier, F; Meissner, M; Melnychuk, D; Merk, M; Michielin, E; Milanes, D A; Minard, M-N; Mitzel, D S; Molina Rodriguez, J; Monroy, I A; Monteil, S; Morandin, M; Morawski, P; Mordà, A; Morello, M J; Moron, J; Morris, A B; Mountain, R; Muheim, F; Mulder, M; Mussini, M; Müller, D; Müller, J; Müller, K; Müller, V; Naik, P; Nakada, T; Nandakumar, R; Nandi, A; Nasteva, I; Needham, M; Neri, N; Neubert, S; Neufeld, N; Neuner, M; Nguyen, A D; Nguyen-Mau, C; Niess, V; Nieswand, S; Niet, R; Nikitin, N; Nikodem, T; Novoselov, A; O'Hanlon, D P; Oblakowska-Mucha, A; Obraztsov, V; Ogilvy, S; Okhrimenko, O; Oldeman, R; Onderwater, C J G; Otalora Goicochea, J M; Otto, A; Owen, P; Oyanguren, A; Pais, P R; Palano, A; Palombo, F; Palutan, M; Panman, J; Papanestis, A; Pappagallo, M; Pappalardo, L L; Pappenheimer, C; Parker, W; Parkes, C; Passaleva, G; Patel, G D; Patel, M; Patrignani, C; Pearce, A; Pellegrino, A; Penso, G; Pepe Altarelli, M; Perazzini, S; Perret, P; Pescatore, L; Petridis, K; Petrolini, A; Petrov, A; Petruzzo, M; Picatoste Olloqui, E; Pietrzyk, B; Pikies, M; Pinci, D; Pistone, A; Piucci, A; Playfer, S; Plo Casasus, M; Poikela, T; Polci, F; Poluektov, A; Polyakov, I; Polycarpo, E; Pomery, G J; Popov, A; Popov, D; Popovici, B; Potterat, C; Price, E; Price, J D; Prisciandaro, J; Pritchard, A; Prouve, C; Pugatch, V; Puig Navarro, A; Punzi, G; Qian, W; Quagliani, R; Rachwal, B; Rademacker, J H; Rama, M; Ramos Pernas, M; Rangel, M S; Raniuk, I; Raven, G; Redi, F; Reichert, S; Dos Reis, A C; Remon Alepuz, C; Renaudin, V; Ricciardi, S; Richards, S; Rihl, M; Rinnert, K; Rives Molina, V; Robbe, P; Rodrigues, A B; Rodrigues, E; Rodriguez Lopez, J A; Rodriguez Perez, P; Rogozhnikov, A; Roiser, S; Romanovskiy, V; Romero Vidal, A; Ronayne, J W; Rotondo, M; Ruf, T; Ruiz Valls, P; Saborido Silva, J J; Sadykhov, E; Sagidova, N; Saitta, B; Salustino Guimaraes, V; Sanchez Mayordomo, C; Sanmartin Sedes, B; Santacesaria, R; Santamarina Rios, C; Santimaria, M; Santovetti, E; Sarti, A; Satriano, C; Satta, A; Saunders, D M; Savrina, D; Schael, S; Schiller, M; Schindler, H; Schlupp, M; Schmelling, M; Schmelzer, T; Schmidt, B; Schneider, O; Schopper, A; Schubiger, M; Schune, M-H; Schwemmer, R; Sciascia, B; Sciubba, A; Semennikov, A; Sergi, A; Serra, N; Serrano, J; Sestini, L; Seyfert, P; Shapkin, M; Shapoval, I; Shcheglov, Y; Shears, T; Shekhtman, L; Shevchenko, V; Shires, A; Siddi, B G; Silva Coutinho, R; Silva de Oliveira, L; Simi, G; Sirendi, M; Skidmore, N; Skwarnicki, T; Smith, E; Smith, I T; Smith, J; Smith, M; Snoek, H; Sokoloff, M D; Soler, F J P; Souza, D; Souza De Paula, B; Spaan, B; Spradlin, P; Sridharan, S; Stagni, F; Stahl, M; Stahl, S; Stefko, P; Stefkova, S; Steinkamp, O; Stenyakin, O; Stevenson, S; Stoica, S; Stone, S; Storaci, B; Stracka, S; Straticiuc, M; Straumann, U; Sun, L; Sutcliffe, W; Swientek, K; Syropoulos, V; Szczekowski, M; Szumlak, T; T'Jampens, S; Tayduganov, A; Tekampe, T; Tellarini, G; Teubert, F; Thomas, C; Thomas, E; van Tilburg, J; Tisserand, V; Tobin, M; Tolk, S; Tomassetti, L; Tonelli, D; Topp-Joergensen, S; Toriello, F; Tournefier, E; Tourneur, S; Trabelsi, K; Traill, M; Tran, M T; Tresch, M; Trisovic, A; Tsaregorodtsev, A; Tsopelas, P; Tully, A; Tuning, N; Ukleja, A; Ustyuzhanin, A; Uwer, U; Vacca, C; Vagnoni, V; Valat, S; Valenti, G; Vallier, A; Vazquez Gomez, R; Vazquez Regueiro, P; Vecchi, S; van Veghel, M; Velthuis, J J; Veltri, M; Veneziano, G; Venkateswaran, A; Vesterinen, M; Viaud, B; Vieira, D; Vieites Diaz, M; Vilasis-Cardona, X; Volkov, V; Vollhardt, A; Voneki, B; Voong, D; Vorobyev, A; Vorobyev, V; Voß, C; de Vries, J A; Vázquez Sierra, C; Waldi, R; Wallace, C; Wallace, R; Walsh, J; Wang, J; Ward, D R; Wark, H M; Watson, N K; Websdale, D; Weiden, A; Whitehead, M; Wicht, J; Wilkinson, G; Wilkinson, M; Williams, M; Williams, M P; Williams, M; Williams, T; Wilson, F F; Wimberley, J; Wishahi, J; Wislicki, W; Witek, M; Wormser, G; Wotton, S A; Wraight, K; Wright, S; Wyllie, K; Xie, Y; Xu, Z; Yang, Z; Yin, H; Yu, J; Yuan, X; Yushchenko, O; Zangoli, M; Zarebski, K A; Zavertyaev, M; Zhang, L; Zhang, Y; Zhang, Y; Zhelezov, A; Zheng, Y; Zhokhov, A; Zhukov, V; Zucchelli, S

    2016-08-19

    A full amplitude analysis of Λ_{b}^{0}→J/ψpπ^{-} decays is performed with a data sample acquired with the LHCb detector from 7 and 8 TeV pp collisions, corresponding to an integrated luminosity of 3  fb^{-1}. A significantly better description of the data is achieved when, in addition to the previously observed nucleon excitations N→pπ^{-}, either the P_{c}(4380)^{+} and P_{c}(4450)^{+}→J/ψp states, previously observed in Λ_{b}^{0}→J/ψpK^{-} decays, or the Z_{c}(4200)^{-}→J/ψπ^{-} state, previously reported in B^{0}→J/ψK^{+}π^{-} decays, or all three, are included in the amplitude models. The data support a model containing all three exotic states, with a significance of more than three standard deviations. Within uncertainties, the data are consistent with the P_{c}(4380)^{+} and P_{c}(4450)^{+} production rates expected from their previous observation taking account of Cabibbo suppression.

  11. Subchronic infusion of the product of inflammation prostaglandin J2 models sporadic Parkinson's disease in mice.

    PubMed

    Pierre, Sha-Ron; Lemmens, Marijke A M; Figueiredo-Pereira, Maria E

    2009-07-25

    Chronic neuroinflammation is implicated in Parkinson's disease (PD). Inflammation involves the activation of microglia and astrocytes that release high levels of prostaglandins. There is a profound gap in our understanding of how cyclooxygenases and their prostaglandin products redirect cellular events to promote PD neurodegeneration. The major prostaglandin in the mammalian brain is prostaglandin D2, which readily undergoes spontaneous dehydration to generate the bioactive cyclopentenone prostaglandins of the J2 series. These J2 prostaglandins are highly reactive and neurotoxic products of inflammation shown in cellular models to impair the ubiquitin/proteasome pathway and cause the accumulation of ubiquitinated proteins. PD is a disorder that exhibits accumulation of ubiquitinated proteins in neuronal inclusions (Lewy bodies). The role of J2 prostaglandins in promoting PD neurodegeneration has not been investigated under in vivo conditions. We addressed the neurodegenerative and behavioral effects of the administration of prostaglandin J2 (PGJ2) simultaneously into the substantia nigra/striatum of adult male FVB mice by subchronic microinjections. One group received unilateral injections of DMSO (vehicle, n = 6) and three groups received PGJ2 [3.4 microg or 6.7 microg (n = 6 per group) or 16.7 microg (n = 5)] per injection. Immunohistochemical and behavioral analyses were applied to assess the effects of the subchronic PGJ2 microinfusions. Immunohistochemical analysis demonstrated a PGJ2 dose-dependent significant and selective loss of dopaminergic neurons in the substantia nigra while the GABAergic neurons were spared. PGJ2 also triggered formation of aggregates immunoreactive for ubiquitin and alpha-synuclein in the spared dopaminergic neurons. Moreover, PGJ2 infusion caused a massive microglia and astrocyte activation that could initiate a deleterious cascade leading to self-sustained progressive neurodegeneration. The PGJ2-treated mice also exhibited

  12. Major contribution of the medial amygdala to hypertension in BPH/2J genetically hypertensive mice.

    PubMed

    Jackson, Kristy L; Palma-Rigo, Kesia; Nguyen-Huu, Thu-Phuc; Davern, Pamela J; Head, Geoffrey A

    2014-04-01

    BPH/2J mice are recognized as a neurogenic model of hypertension primarily based on overactivity of the sympathetic nervous system and greater neuronal activity in key autonomic cardiovascular regulatory brain regions. The medial amygdala (MeAm) is a forebrain region that integrates the autonomic response to stress and is the only region found to have greater Fos during the night and daytime in BPH/2J compared with BPN/3J mice. To determine the contribution of the MeAm to hypertension, the effect of neuronal ablation on blood pressure (BP) was assessed in BPH/2J (n=7) and normotensive BPN/3J mice (n=7). Mice were preimplanted with radiotelemetry devices to measure 24-hour BP and cardiovascular responses to stress, before and 1 to 3 weeks after bilateral lesions of the MeAm. Baseline BP was 121±4 mm Hg in BPH/2J and 101±2 mm Hg in BPN/3J mice (Pstrain<0.001). MeAm lesions reduced BP by 11±2 mm Hg in BPH/2J mice (Plesion<0.001) but had no effect in BPN/3J mice. The hypotensive effect of lesions in BPH/2J mice was similar during both day and night, suggesting that the MeAm has tonic effects on BP, but the pressor response to stress was maintained in both strains. Midfrequency BP power was attenuated in both strains (Plesion<0.05) and the depressor responses to pentolinium after enalaprilat pretreatment was attenuated after lesions in BPH/2J mice (Plesion<0.001; n=3). These findings indicate that the MeAm provides a tonic contribution to hypertension in BPH/2J mice, which is independent of its role in stress reactivity or circadian BP influences.

  13. Detection of X-ray flares from AX J1714.1-3912, the unidentified source near RX J1713.7-3946

    NASA Astrophysics Data System (ADS)

    Miceli, Marco; Bamba, Aya

    2018-04-01

    Context. Molecular clouds are predicted to emit nonthermal X-rays when they are close to particle-accelerating supernova remnants (SNRs), and the hard X-ray source AX J1714.1-3912, near the SNR RX J1713.7-3946, has long been considered a candidate for diffuse nonthermal emission associated with cosmic rays diffusing from the remnant to a closeby molecular cloud. Aim. We aim at ascertaining the nature of this source by analyzing two dedicated X-ray observations performed with Suzaku and Chandra. Methods: We extracted images from the data in various energy bands, spectra, and light curves and studied the long-term evolution of the X-ray emission on the basis of the 4.5 yr time separation between the two observations. Results: We found that there is no diffuse emission associated with AX J1714.1-3912, which is instead the point-like source CXOU J171343.9-391205. We discovered rapid time variability (timescale 103 s), together with a high intrinsic absorption and a hard nonthermal spectrum (power law with photon index Γ 1.4). We also found that the X-ray flux of the source drops down by 1-2 orders of magnitude on a timescale of a few years. Conclusions: Our results suggest a possible association between AX J1714.1-3912 and a previously unknown supergiant fast X-ray transient, although further follow-up observations are necessary to prove this association definitively.

  14. Effect of Environmental Enrichment on Aggression in BALB/cJ and BALB/cByJ Mice Monitored by Using an Automated System.

    PubMed

    Giles, Jareca M; Whitaker, Julia W; Moy, Sheryl S; Fletcher, Craig A

    2018-04-18

    Aggression among mice remains a common undesirable problem in laboratory settings, and animal welfare and scientific outcomes may become compromised depending on the severity of aggression. This study evaluated the effect of cage enrichment comprising a bilevel, mounted 'mezzanine' compared with a cotton square or shelter on intracage male aggression over a 6-wk period. Our first study involved home-cage behavioral challenges to male mice from a high aggression substrain (BALB/cJ) and low-aggression substrain (BALB/cByJ). Aggressive interactions and locomotor activity were scored manually and then compared with measures of activity obtained by using a continuous automated home-cagemonitoring system, the Digital Ventilated Caging (DVC) system. BALB/cJ mice exhibited similar levels of aggression acrosshousing conditions, whereas BALB/cByJ mice had lower aggression when housed with a mezzanine. In the second study,videorecordings and continuous DVC automated measures were collected over 24 h and divided into 12-h light and dark phases. BALB/cByJ mice-but not BALB/cJ-mice had increased aggressive behaviors during the dark phase. However, the DVC detected higher activity levels during the dark phase, compared with the light phase, in both substrains. Elevated activity levels recorded by the DVC correlated with fighting bouts and high levels of locomotion. These results show that a bilevel structural form of enrichment reduces aggression, depending on the BALB/c substrain, and confirms higher aggression levels in the BALB/cJ substrain. In addition, our findings provide evidence that the DVC is effective in identifying mouse cages with patterns of high activity levels, signaling possible aggression incidences, thus potentially allowing for early intervention and consequently improving animal welfare.

  15. 76 FR 2799 - Amendment of Jet Route J-93; CA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-18

    ...; Airspace Docket No. 10-AWP-4] RIN 2120-AA66 Amendment of Jet Route J-93; CA AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Jet Route J-93 in California between...) to amend J-93, (75 FR 66344). Interested parties were invited to participate in this rulemaking...

  16. 26 CFR 1.904(j)-0 - Outline of regulation provisions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 9 2010-04-01 2010-04-01 false Outline of regulation provisions. 1.904(j)-0 Section 1.904(j)-0 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Income from Sources Without the United States § 1.904(j)-0 Outline of...

  17. Michael J. Meaney: Award for Distinguished Scientific Contributions

    ERIC Educational Resources Information Center

    American Psychologist, 2012

    2012-01-01

    Presents Michael J. Meaney as one of the winners of the American Psychological Association's Award for Distinguished Scientific Contributions (2012). Michael J. Meaney has taken the phenomenon of "handling" of newborn rats and opened a new area of investigation that has given new meaning to epigenetics via his work demonstrating transgenerational…

  18. Reduced Sodium Current in the Lateral Ventricular Wall Induces Inferolateral J-Waves.

    PubMed

    Meijborg, Veronique M F; Potse, Mark; Conrath, Chantal E; Belterman, Charly N W; De Bakker, Jacques M T; Coronel, Ruben

    2016-01-01

    J-waves in inferolateral leads are associated with a higher risk for idiopathic ventricular fibrillation. We aimed to test potential mechanisms (depolarization or repolarization dependent) responsible for inferolateral J-waves. We hypothesized that inferolateral J-waves can be caused by regional delayed activation of myocardium that is activated late during normal conditions. Computer simulations were performed to evaluate how J-point elevation is influenced by reducing sodium current conductivity (GNa), increasing transient outward current conductivity (Gto), or cellular uncoupling in three predefined ventricular regions (lateral, anterior, or septal). Two pig hearts were Langendorff-perfused with selective perfusion with a sodium channel blocker of lateral or anterior/septal regions. Volume-conducted pseudo-electrocardiograms (ECG) were recorded to detect the presence of J-waves. Epicardial unipolar electrograms were simultaneously recorded to obtain activation times (AT). Simulation data showed that conduction slowing, caused by reduced sodium current, in lateral, but not in other regions induced inferolateral J-waves. An increase in transient outward potassium current or cellular uncoupling in the lateral zone elicited slight J-point elevations which did not meet J-wave criteria. Additional conduction slowing in the entire heart attenuated J-waves and J-point elevations on the ECG, because of masking by the QRS. Experimental data confirmed that conduction slowing attributed to sodium channel blockade in the left lateral but not in the anterior/septal ventricular region induced inferolateral J-waves. J-waves coincided with the delayed activation. Reduced sodium current in the left lateral ventricular myocardium can cause inferolateral J-waves on the ECG.

  19. J-Earth: An Essential Resource for Terrestrial Remote Sensing and Data Analysis

    NASA Astrophysics Data System (ADS)

    Dunn, S.; Rupp, J.; Cheeseman, S.; Christensen, P. R.; Prashad, L. C.; Dickenshied, S.; Anwar, S.; Noss, D.; Murray, K.

    2011-12-01

    There is a need for a software tool that has the ability to display and analyze various types of earth science and social data through a simple, user-friendly interface. The J-Earth software tool has been designed to be easily accessible for download and intuitive use, regardless of the technical background of the user base. This tool does not require courses or text books to learn to use, yet is powerful enough to allow a more general community of users to perform complex data analysis. Professions that will benefit from this tool range from geologists, geographers, and climatologists to sociologists, economists, and ecologists as well as policy makers. J-Earth was developed by the Arizona State University Mars Space Flight Facility as part of the JMARS (Java Mission-planning and Analysis for Remote Sensing) suite of open-source tools. The program is a Geographic Information Systems (GIS) application used for viewing and processing satellite and airborne remote sensing data. While the functionality of JMARS has historically focused on the research needs of the planetary science community, J-Earth has been designed for a much broader Earth-based user audience. NASA instrument products accessible within J-Earth include data from ASTER, GOES, Landsat, MODIS, and TIMS. While J-Earth contains exceptionally comprehensive and high resolution satellite-derived data and imagery, this tool also includes many socioeconomic data products from projects lead by international organizations and universities. Datasets used in J-Earth take the form of grids, rasters, remote sensor "stamps", maps, and shapefiles. Some highly demanded global datasets available within J-Earth include five levels of administrative/political boundaries, climate data for current conditions as well as models for future climates, population counts and densities, land cover/land use, and poverty indicators. While this application does share the same powerful functionality of JMARS, J-Earth's apperance is

  20. 3D J-Integral Capability in Grizzly

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Spencer, Benjamin; Backman, Marie; Chakraborty, Pritam

    2014-09-01

    This report summarizes work done to develop a capability to evaluate fracture contour J-Integrals in 3D in the Grizzly code. In the current fiscal year, a previously-developed 2D implementation of a J-Integral evaluation capability has been extended to work in 3D, and to include terms due both to mechanically-induced strains and due to gradients in thermal strains. This capability has been verified against a benchmark solution on a model of a curved crack front in 3D. The thermal term in this integral has been verified against a benchmark problem with a thermal gradient. These developments are part of a largermore » effort to develop Grizzly as a tool that can be used to predict the evolution of aging processes in nuclear power plant systems, structures, and components, and assess their capacity after being subjected to those aging processes. The capabilities described here have been developed to enable evaluations of Mode- stress intensity factors on axis-aligned flaws in reactor pressure vessels. These can be compared with the fracture toughness of the material to determine whether a pre-existing flaw would begin to propagate during a pos- tulated pressurized thermal shock accident. This report includes a demonstration calculation to show how Grizzly is used to perform a deterministic assessment of such a flaw propagation in a degraded reactor pressure vessel under pressurized thermal shock conditions. The stress intensity is calculated from J, and the toughness is computed using the fracture master curve and the degraded ductile to brittle transition temperature.« less

  1. Observations of J002E3: Possible Discovery of an Apollo Rocket Body

    NASA Astrophysics Data System (ADS)

    Jorgensen, K.; Rivkin, A.; Binzel, R.; Whitely, R.; Hergenrother, C.; Chodas, P.; Chesley, S.; Vilas, F.

    2003-05-01

    In early September 2002, spectral and photometric observations of J002E3 were made at IRTF and Mt. Biglow in an effort to determine whether the object was an asteroid or a human-made. Early observations yielded a possible spin-rate and orientation. Additional spectral observations were completed in May 2003 at the Air Force Maui Optical Supercomputing (AMOS) site. Through the modeling of common spacecraft materials, the observations of J002E3 show a strong correlation of absorption features to a combination of human-made materials including white paint, black paint, and aluminum. Absorption features in the near IR show a strong correlation with paint containing a titanium-oxide semiconductor. Using the material model and the orbital information, it was concluded that J002E3 is a human-made object from an Apollo rocket upperstage, most likely Apollo 12. In addition, the J002E3 observations were compared to spectral observations of other rocket bodies launched during a similar time and the results agree well. Results from the observations and modeling will be presented. This work has been a collaboration of governmental agencies, education institutions, and amateur astronomers. Funding agencies include National Research Council, NASA JSC, MIT, University of Arizona, and JPL.

  2. The ortho:para-H_2 ratio in C- and J-type shocks

    NASA Astrophysics Data System (ADS)

    Wilgenbus, D.; Cabrit, S.; Pineau des Forêts, G.; Flower, D. R.

    2000-04-01

    We have computed extensive grids of models of both C- and J-type planar shock waves, propagating in dark, cold molecular clouds, in order to study systematically the behaviour of the ortho:para-H_2 ratio. Careful attention was paid to both macroscopic (dynamical) and microscopic (chemical reactions and collisional population transfer in H_2) aspects. We relate the predictions of the models to observational determinations of the ortho:para-H_2 ratio using both pure rotational lines and rovibrational lines. As an illustration, we consider ISO and ground-based H_2 observations of HH 54. Neither planar C-type nor planar J-type shocks appear able to account fully for these observations. Given the additional constraints provided by the observed ortho:para H_2 ratios, a C-type bowshock, or a C-type precursor followed by a J-type shock, remain as plausible models. Tables~2a-f and 4a-f are only available in electronic form at the CDS via anonymous ftp to cdsarc.u-strasbg.fr (130.79.128.5) or via http://cdsweb.u-strasbg.fr/Abstract.html

  3. Omigapil treatment decreases fibrosis and improves respiratory rate in dy(2J) mouse model of congenital muscular dystrophy.

    PubMed

    Yu, Qing; Sali, Arpana; Van der Meulen, Jack; Creeden, Brittany K; Gordish-Dressman, Heather; Rutkowski, Anne; Rayavarapu, Sree; Uaesoontrachoon, Kitipong; Huynh, Tony; Nagaraju, Kanneboyina; Spurney, Christopher F

    2013-01-01

    Congenital muscular dystrophy is a distinct group of diseases presenting with weakness in infancy or childhood and no current therapy. One form, MDC1A, is the result of laminin alpha-2 deficiency and results in significant weakness, respiratory insufficiency and early death. Modification of apoptosis is one potential pathway for therapy in these patients. dy(2J) mice were treated with vehicle, 0.1 mg/kg or 1 mg/kg of omigapil daily via oral gavage over 17.5 weeks. Untreated age matched BL6 mice were used as controls. Functional, behavioral and histological measurements were collected. dy(2J) mice treated with omigapil showed improved respiratory rates compared to vehicle treated dy(2J) mice (396 to 402 vs. 371 breaths per minute, p<0.03) and similar to control mice. There were no statistical differences in normalized forelimb grip strength between dy(2J) and controls at baseline or after 17.5 weeks and no significant differences seen among the dy(2J) treatment groups. At 30-33 weeks of age, dy(2J) mice treated with 0.1 mg/kg omigapil showed significantly more movement time and less rest time compared to vehicle treated. dy(2J) mice showed normal cardiac systolic function throughout the trial. dy(2J) mice had significantly lower hindlimb maximal (p<0.001) and specific force (p<0.002) compared to the control group at the end of the trial. There were no statistically significant differences in maximal or specific force among treatments. dy(2J) mice treated with 0.1 mg/kg/day omigapil showed decreased percent fibrosis in both gastrocnemius (p<0.03) and diaphragm (p<0.001) compared to vehicle, and in diaphragm (p<0.013) when compared to 1 mg/kg/day omigapil treated mice. Omigapil treated dy(2J) mice demonstrated decreased apoptosis. Omigapil therapy (0.1 mg/kg) improved respiratory rate and decreased skeletal and respiratory muscle fibrosis in dy(2J) mice. These results support a putative role for the use of omigapil in laminin deficient congenital muscular dystrophy

  4. Coherent J / ψ photoproduction in hadronic heavy-ion collisions

    DOE PAGES

    Zha, W.; Klein, S. R.; Ma, R.; ...

    2018-04-19

    Significant excesses of J/ yield at very low transverse momentum (p T < 0:3 GeV/c) were observed by the ALICE and STAR collaborations in peripheral hadronic A+A collisions. This is a Sign of coherent photoproduction of J/ψ in violent hadronic interactions. Theoretically, the photoproduction of J= in hadronic collisions raises questions about how spectator and non-spectator nucleons participate in the coherent reaction. We argue that the strong interactions in the overlapping region of incoming nuclei may disturb the coherent production, leaving room for different coupling assumptions. The destructive interference between photoproduction on ions moving in opposite directions also needs tomore » be included. This letter presents calculations of J/ψ production from coherent photon-nucleus (γ+A → J/ψ +A) interactions in hadronic A+A collisions at RHIC and LHC energies with both nucleus and spectator coupling hypotheses. The integrated yield of coherent J/ψ as a function of centrality is found to be significantly different, especially towards central collisions, for different coupling scenarios. Differential distributions as a function of transverse momentum, azimuthal angle and rapidity in different centrality bins are also shown, and found to be more sensitive to the Pomeron coupling than to the photon coupling. Lastly, these predictions call for future experimental measurements to help better understand the coherent interaction in hadronic heavy-ion collisions.« less

  5. Coherent J /ψ photoproduction in hadronic heavy-ion collisions

    NASA Astrophysics Data System (ADS)

    Zha, W.; Klein, S. R.; Ma, R.; Ruan, L.; Todoroki, T.; Tang, Z.; Xu, Z.; Yang, C.; Yang, Q.; Yang, S.

    2018-04-01

    Significant excesses of J /ψ yield at very low transverse momentum (pT<0.3 GeV/c ) were observed by the ALICE and STAR collaborations in peripheral hadronic A +A collisions. This is a sign of coherent photoproduction of J /ψ in violent hadronic interactions. Theoretically, the photoproduction of J /ψ in hadronic collisions raises questions about how spectator and nonspectator nucleons participate in the coherent reaction. We argue that the strong interactions in the overlapping region of incoming nuclei may disturb the coherent production, leaving room for different coupling assumptions. The destructive interference between photoproduction on ions moving in opposite directions also needs to be included. This paper presents calculations of J /ψ production from coherent photon-nucleus (γ +A →J /ψ +A ) interactions in hadronic A +A collisions at BNL Relativistic Heavy Ion Collider and CERN Large Hadron Collider energies with both nucleus and spectator coupling hypotheses. The integrated yield of coherent J /ψ as a function of centrality is found to be significantly different, especially towards central collisions, for different coupling scenarios. Differential distributions as a function of transverse momentum, azimuthal angle, and rapidity in different centrality bins are also shown, and found to be more sensitive to the Pomeron coupling than to the photon coupling. These predictions call for future experimental measurements to help better understand the coherent interaction in hadronic heavy-ion collisions.

  6. Coherent J / ψ photoproduction in hadronic heavy-ion collisions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zha, W.; Klein, S. R.; Ma, R.

    Significant excesses of J/ yield at very low transverse momentum (p T < 0:3 GeV/c) were observed by the ALICE and STAR collaborations in peripheral hadronic A+A collisions. This is a Sign of coherent photoproduction of J/ψ in violent hadronic interactions. Theoretically, the photoproduction of J= in hadronic collisions raises questions about how spectator and non-spectator nucleons participate in the coherent reaction. We argue that the strong interactions in the overlapping region of incoming nuclei may disturb the coherent production, leaving room for different coupling assumptions. The destructive interference between photoproduction on ions moving in opposite directions also needs tomore » be included. This letter presents calculations of J/ψ production from coherent photon-nucleus (γ+A → J/ψ +A) interactions in hadronic A+A collisions at RHIC and LHC energies with both nucleus and spectator coupling hypotheses. The integrated yield of coherent J/ψ as a function of centrality is found to be significantly different, especially towards central collisions, for different coupling scenarios. Differential distributions as a function of transverse momentum, azimuthal angle and rapidity in different centrality bins are also shown, and found to be more sensitive to the Pomeron coupling than to the photon coupling. Lastly, these predictions call for future experimental measurements to help better understand the coherent interaction in hadronic heavy-ion collisions.« less

  7. Hole pairing and ground state properties of high-Tc superconductivity within the t-t'-J-V model

    NASA Astrophysics Data System (ADS)

    Roy, Krishanu; Pal, Papiya; Nath, Subhadip; Ghosh, Nanda Kumar

    2018-04-01

    The t-t'-J-V model, one of the realistic models for studying high-Tc cuprates, has been investigated to explore the hole pairing and other ground state properties using exact diagonalization (ED) technique with 2 holes in a small 8-site cluster. The role of next-nearest-neighbor (NNN) hopping and nearest-neighbor (NN) Coulomb repulsion has been considered. It appears that qualitative behavior of the ground state energies of an 8-site and 16- or 18-site cluster is similar. Results show that a small short-ranged antiferromagnetic (AF) correlation exists in the 2 hole case which is favored by large V/t. A superconducting phase emerges at 0 ≤ V/t ≤ 4J. Hole-hole correlation calculation also suggests that the two holes of the pair are either at |i - j| = 1 or √2. Negative t'/t suppresses the possibility of pairing of holes. Though s-wave pairing susceptibility is dominant, pairing correlation length calculation indicates that the long range pairing, which is suitable for superconductivity, is in the d-wave channel. Both s- and d-wave pairing susceptibility gets suppressed by V/t while d-(s-) wave susceptibility gets favored (suppressed) by t'/t. The charge gap shows a gapped behavior while a spin-gapless region exists at small V/t for finite t'/t.

  8. Swift J1822.3-1606: Enhanced Swift-XRT position

    NASA Astrophysics Data System (ADS)

    Pagani, C.; Beardmore, A. P.; Kennea, J. A.

    2011-07-01

    Using 1046 s of XRT Photon Counting mode data and 1 UVOT image for Swift J1822.3-1606, we find an astrometrically corrected X-ray position (using the XRT-UVOT alignment and matching UVOT field sources to the USNO-B1 catalogue) of RA, Dec = 275.57500, -16.07412 which is equivalent to: RA (J2000): 18h 22m 18.00s Dec (J2000): -16d 04' 26.8" with an uncertainty of 1.8 arcsec (radius, 90% confidence).

  9. High Intensity Proton Accelerator Project in Japan (J-PARC).

    PubMed

    Tanaka, Shun-ichi

    2005-01-01

    The High Intensity Proton Accelerator Project, named as J-PARC, was started on 1 April 2001 at Tokai-site of JAERI. The accelerator complex of J-PARC consists of three accelerators: 400 MeV Linac, 3 GeV rapid cycle synchrotron and 50 GeV synchrotron; and four major experimental facilities: Material and Life Science Facility, Nuclear and Particle Physics Facility, Nuclear Transmutation Experiment Facility and Neutrino Facility. The outline of the J-PARC is presented with the current status of construction.

  10. Assessment of the Intestinal Barrier with Five Different Permeability Tests in Healthy C57BL/6J and BALB/cJ Mice.

    PubMed

    Volynets, Valentina; Reichold, Astrid; Bárdos, Gyöngyi; Rings, Andreas; Bleich, André; Bischoff, Stephan C

    2016-03-01

    Intestinal permeability is thought to be of major relevance for digestive and nutrition-related diseases, and therefore has been studied in numerous mouse models of disease. However, it is unclear which tools are the preferable ones, and how normal values should be defined. To compare different in vivo permeability tests in healthy mice of commonly used genetic backgrounds. We assessed the intestinal barrier in male and female C57BL/6J and BALB/cJ mice of different ages, using four orally administered permeability markers, FITC-dextran 4000 (FITC-D4000) and ovalbumin (OVA) measured in plasma, and polyethylene glycol (PEG) and lactulose/mannitol (Lac/Man) measured in urine, and by assessing lipopolysaccharide (LPS) in portal vein plasma. After gavage, FITC-D4000, OVA, Lac/Man, and PEG400, but not PEG4000, were detectable in plasma or urine. Female mice tended to have a higher permeability according to the FITC-D4000, OVA, and PEG400 tests, but the Lac/Man ratio was higher in males. No significant differences between the two mouse strains of young and old mice were observed except for mannitol recovery, which was higher in BALB/cJ mice compared to C57BL/6J mice (p < 0.05). Virtually no LPS was detected in healthy mice. For all markers, normal values have been defined based on 5th-95th percentile ranges of our data. Selected oral permeability tests, such as FITC-D4000, OVA, PEG400, and Lac/Man, as well as LPS measurements in portal vein plasma, could be suitable for the evaluation of the intestinal barrier in mice, if used in a standardized way.

  11. Differences in the onset mode of ventricular tachyarrhythmia between patients with J wave in anterior leads and those with J wave in inferolateral leads.

    PubMed

    Kamakura, Tsukasa; Wada, Mitsuru; Ishibashi, Kohei; Inoue, Yuko Y; Miyamoto, Koji; Okamura, Hideo; Nagase, Satoshi; Noda, Takashi; Aiba, Takeshi; Yasuda, Satoshi; Shimizu, Wataru; Kamakura, Shiro; Kusano, Kengo

    2017-04-01

    The pathophysiological mechanism of J wave in anterior leads (A-leads) and inferolateral leads (L-leads) remains unclear. We investigated the onset mode and circadian distribution of ventricular tachyarrhythmia (VTA) episodes between patients with early repolarization syndrome (ERS) and Brugada syndrome (BrS). The study enrolled 35 patients with ERS and 52 patients with type 1 BrS with spontaneous ventricular fibrillation who were divided into 4 groups: ERS(A+L) (n = 15), patients with ERS who had a non-type 1 Brugada pattern electrocardiogram in any A-leads (second to fourth intercostal spaces) in control and/or after drug provocation tests; ERS(L) (n = 20), patients with ERS with J wave only in L-leads; BrS(A) (n = 24), patients with BrS without J wave in L-leads; and BrS(A+L) (n = 28), patients with BrS with J wave in L-leads. The onset mode of 206 VTAs obtained from electrocardiograms or implantable cardioverter-defibrillators and the circadian distribution of 352 VTAs were investigated in the 4 groups. Three groups with J wave in A-leads, ERS(A+L), BrS(A), and BrS(A+L), had higher incidences of nocturnal (63%, 43%, and 47%, respectively) and sudden onset VTAs (67%, 97%, and 86%, respectively) with longer coupling intervals of premature ventricular contractions (388.8, 397.3, and 385.6 ms, respectively) than the ERS(L) group with J wave only in L-leads (25%, P = .0019; 19%, P < .0001; and 330.6 ms, P = .0004, respectively), the last of which mainly displayed VTAs with a short-long-short sequence. The onset mode of VTAs was different between patients with J wave in A-leads and patients with J wave in only L-leads. The underlying mechanism of J wave may differ between A-leads and L-leads. Copyright © 2016 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.

  12. Circulating ApoJ is closely associated with insulin resistance in human subjects.

    PubMed

    Seo, Ji A; Kang, Min-Cheol; Ciaraldi, Theodore P; Kim, Sang Soo; Park, Kyong Soo; Choe, Charles; Hwang, Won Min; Lim, Dong Mee; Farr, Olivia; Mantzoros, Christos; Henry, Robert R; Kim, Young-Bum

    2018-01-01

    Insulin resistance is a major risk factor for type 2 diabetes. ApolipoproteinJ (ApoJ) has been implicated in altered pathophysiologic states including cardiovascular and Alzheimer's disease. However, the function of ApoJ in regulation of glucose homeostasis remains unclear. This study sought to determine whether serum ApoJ levels are associated with insulin resistance in human subjects and if they change after interventions that improve insulin sensitivity. Serum ApoJ levels and insulin resistance status were assessed in nondiabetic (ND) and type 2 diabetic (T2D) subjects. The impacts of rosiglitazone or metformin therapy on serum ApoJ levels and glucose disposal rate (GDR) during a hyperinsulinemic/euglycemic clamp were evaluated in a separate cohort of T2D subjects. Total ApoJ protein or that associated with the HDL and LDL fractions was measured by immunoblotting or ELISA. Fasting serum ApoJ levels were greatly elevated in T2D subjects (ND vs T2D; 100±8.3 vs. 150.6±8.5AU, P<0.0001). Circulating ApoJ levels strongly correlated with fasting glucose, fasting insulin, HOMA-IR, and BMI. ApoJ levels were significantly and independently associated with HOMA-IR, even after adjustment for age, sex, and BMI. Rosiglitazone treatment in T2D subjects resulted in a reduction in serum ApoJ levels (before vs. after treatment; 100±13.9 vs. 77±15.2AU, P=0.015), whereas metformin had no effect on ApoJ levels. The change in ApoJ levels during treatment was inversely associated with the change in GDR. Interestingly, ApoJ content in the LDL fraction was inversely associated with HOMA-IR. Serum ApoJ levels are closely correlated with the magnitude of insulin resistance regardless of obesity, and decrease along with improvement of insulin resistance in response only to rosiglitazone in type 2 diabetes. Copyright © 2017 Elsevier Inc. All rights reserved.

  13. XTE J1946+274 = GRO J1944+26: An Enigmatic Be/X-Ray Binary

    NASA Technical Reports Server (NTRS)

    Wilson, Colleen A.; Finger, Mark H.; Coe, M. J.; Negueruela, Ignacio

    2003-01-01

    XTE J1946+274 = GRO J1944+26 is a 15.8 s Be/X-ray pulsar discovered simultaneously in 1998 September with the Burst and Transient Source Experiment (BATSE) on the Compton Gamma Ray Observatory (CGRO) and the All-Sky Monitor (ASM) on the Rossi X-Ray Timing Explorer (RXTE). Here we present new results from BATSE and RXTE including a pulse timing analysis, spectral analysis, and evidence for an accretion disk. Our pulse timing analysis yielded an orbital period of 169.2 days, a moderate eccentricity 0.33, and implied a mass function of 9.7 solar masses. We observed evidence for an accretion disk, a correlation between measured spin-up rate and flux, which was fitted to obtain a distance estimate of 9.5 +/- 2.9 kpc. XTE J1946+274 remained active from 1998 September to 2001 July, undergoing 13 outbursts that were not locked in orbital phase. Comparing RXTE Proportional Counter Array observations from the initial bright outburst in 1998 and the last pair of outbursts in 2001, we found energy and intensity-dependent pulse profile variations in both outbursts and hardening spectra with increasing intensity during the fainter 2001 outbursts. In 2001 July, optical H alpha observations indicated that a density perturbation appeared in the Be disk as the X-ray outbursts ceased. We propose that the equatorial plane of the Be star is inclined with respect to the orbital plane in this system and that this inclination may be a factor in the unusual outburst behavior of the system.

  14. HESS J1640-465 and HESS J1641-463: Two Intriguing TeV Sources in Light of New Fermi-LAT Observations

    NASA Astrophysics Data System (ADS)

    Lemoine-Goumard, M.; Grondin, M.-H.; Acero, F.; Ballet, J.; Laffon, H.; Reposeur, T.

    2014-10-01

    We report on γ-ray analysis of the region containing the bright TeV source HESS J1640-465 and the close-by TeV source HESS J1641-463 using 64 months of observations with the Fermi Large Area Telescope (LAT). Previously only one GeV source was reported in this region and was associated with HESS J1640-465. With an increased data set and the improved sensitivity afforded by the reprocessed data (P7REP) of the LAT, we now report the detection, morphological study, and spectral analysis of two distinct sources above 100 MeV. The softest emission in this region comes from the TeV source HESS J1641-463 which is well fitted with a power law of index Γ = 2.47 ± 0.05 ± 0.06 and presents no significant γ-ray signal above 10 GeV, which contrasts with its hard spectrum at TeV energies. The Fermi-LAT spectrum of the second TeV source, HESS J1640-465 is well described by a power-law shape of index Γ = 1.99 ± 0.04 ± 0.07 that links up naturally with the spectral data points obtained by the High Energy Stereoscopic System (H.E.S.S.). These new results provide new constraints concerning the identification of these two puzzling γ-ray sources.

  15. Spatially Resolving the Very High Energy Emission from MGRO J2019+37 with VERITAS

    NASA Astrophysics Data System (ADS)

    Aliu, E.; Aune, T.; Behera, B.; Beilicke, M.; Benbow, W.; Berger, K.; Bird, R.; Bouvier, A.; Buckley, J. H.; Bugaev, V.; Cerruti, M.; Chen, X.; Ciupik, L.; Connolly, M. P.; Cui, W.; Dumm, J.; Dwarkadas, V. V.; Errando, M.; Falcone, A.; Federici, S.; Feng, Q.; Finley, J. P.; Fleischhack, H.; Fortin, P.; Fortson, L.; Furniss, A.; Galante, N.; Gillanders, G. H.; Gotthelf, E. V.; Griffin, S.; Griffiths, S. T.; Grube, J.; Gyuk, G.; Hanna, D.; Holder, J.; Hughes, G.; Humensky, T. B.; Johnson, C. A.; Kaaret, P.; Kargaltsev, O.; Kertzman, M.; Khassen, Y.; Kieda, D.; Krennrich, F.; Lang, M. J.; Madhavan, A. S.; Maier, G.; McArthur, S.; McCann, A.; Millis, J.; Moriarty, P.; Mukherjee, R.; Nieto, D.; O'Faoláin de Bhróithe, A.; Ong, R. A.; Otte, A. N.; Pandel, D.; Park, N.; Pohl, M.; Popkow, A.; Prokoph, H.; Quinn, J.; Ragan, K.; Rajotte, J.; Reyes, L. C.; Reynolds, P. T.; Richards, G. T.; Roache, E.; Roberts, M.; Sembroski, G. H.; Shahinyan, K.; Smith, A. W.; Staszak, D.; Telezhinsky, I.; Tucci, J. V.; Tyler, J.; Vincent, S.; Wakely, S. P.; Weinstein, A.; Welsing, R.; Wilhelm, A.; Williams, D. A.; Zitzer, B.

    2014-06-01

    We present very high energy (VHE) imaging of MGRO J2019+37 obtained with the VERITAS observatory. The bright extended (~2°) unidentified Milagro source is located toward the rich star formation region Cygnus-X. MGRO J2019+37 is resolved into two VERITAS sources. The faint, point-like source VER J2016+371 overlaps CTB 87, a filled-center remnant (SNR) with no evidence of a supernova remnant shell at the present time. Its spectrum is well fit in the 0.65-10 TeV energy range by a power-law model with photon index 2.3 ± 0.4. VER J2019+378 is a bright extended (~1°) source that likely accounts for the bulk of the Milagro emission and is notably coincident with PSR J2021+3651 and the star formation region Sh 2-104. Its spectrum in the range 1-30 TeV is well fit with a power-law model of photon index 1.75 ± 0.3, among the hardest values measured in the VHE band, comparable to that observed near Vela-X. We explore the unusual spectrum and morphology in the radio and X-ray bands to constrain possible emission mechanisms for this source.

  16. Wrestling J. B. Nash.

    ERIC Educational Resources Information Center

    Ellis, Gary D.

    This paper focuses on how between 1965 and the present, the field of recreation has and has not accomplished the goals of author and educator J. B. Nash's in regard to recreation, physical education, and health, focusing on public recreation sponsored by city governments, county governments, and special tax districts. The paper looks at Nash's…

  17. 28 CFR 0.29j - Law enforcement authority.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 1 2013-07-01 2013-07-01 false Law enforcement authority. 0.29j Section...-Office of the Inspector General § 0.29j Law enforcement authority. Subject to guidelines promulgated by...) Detect and assist in the prosecution of crimes in violation of the laws of the United States and to...

  18. Evolving J waves prior to ventricular fibrillation postoperative coronary bypass.

    PubMed

    Kitazawa, Hitoshi; Wakasugi, Takayuki; Sugimoto, Tsutomu; Yamamoto, Kazuo; Yoshii, Shinpei; Aizawa, Yoshifusa

    2011-01-01

    A 74-year-old man without history of ventricular arrhythmias underwent coronary bypass surgery for 3-vessel disease. On the 4th postoperative day, he developed ventricular fibrillation (VF). His monitored ECG showed no elevation of the ST-segment and no prolongation of QT interval, but evolving J waves prior to VF were shown. These J waves gradually decreased after defibrillation. The subsequent angiography revealed patent grafts and normal left ventricular function. J waves reappeared in inferior leads when contrast medium was injected into the coronary artery. Therefore, evolving J wave can be a marker of latent ischemia and a predictor of VF.

  19. STS-28/51J - OFFICIAL CREW INSIGNIA

    NASA Image and Video Library

    1985-09-06

    S85-39862 (1 Sept. 1985) --- The 51-J mission insignia, designed by Atlantis's first crew, pays tribute to the Statue of Liberty and the ideas it symbolizes. The historical gateway figure bears additional significance for astronauts Karol J. Bobko, mission commander; and Ronald J. Grabe, pilot, both New York natives. Other members of the five-man crew, whose surnames encircle the artwork, are Robert L. Stewart and David C. Hilmers, mission specialists; and William A. Pailes, payload specialist. The NASA insignia design for space shuttle flights is reserved for use by the astronauts and for other official use as the NASA Administrator may authorize. Public availability has been approved only in the forms of illustrations by the various news media. When and if there is any change in this policy, which is not anticipated, the change will be publicly announced. Photo credit: NASA

  20. Observation of J/ψp Resonances Consistent with Pentaquark States in Λ_{b}^{0}→J/ψK^{-}p Decays.

    PubMed

    Aaij, R; Adeva, B; Adinolfi, M; Affolder, A; Ajaltouni, Z; Akar, S; Albrecht, J; Alessio, F; Alexander, M; Ali, S; Alkhazov, G; Alvarez Cartelle, P; Alves, A A; Amato, S; Amerio, S; Amhis, Y; An, L; Anderlini, L; Anderson, J; Andreassi, G; Andreotti, M; Andrews, J E; Appleby, R B; Aquines Gutierrez, O; Archilli, F; d'Argent, P; Artamonov, A; Artuso, M; Aslanides, E; Auriemma, G; Baalouch, M; Bachmann, S; Back, J J; Badalov, A; Baesso, C; Baldini, W; Barlow, R J; Barschel, C; Barsuk, S; Barter, W; Batozskaya, V; Battista, V; Bay, A; Beaucourt, L; Beddow, J; Bedeschi, F; Bediaga, I; Bel, L J; Bellee, V; Belloli, N; Belyaev, I; Ben-Haim, E; Bencivenni, G; Benson, S; Benton, J; Berezhnoy, A; Bernet, R; Bertolin, A; Bettler, M-O; van Beuzekom, M; Bien, A; Bifani, S; Billoir, P; Bird, T; Birnkraut, A; Bizzeti, A; Blake, T; Blanc, F; Blouw, J; Blusk, S; Bocci, V; Bondar, A; Bondar, N; Bonivento, W; Borghi, S; Borsato, M; Bowcock, T J V; Bowen, E; Bozzi, C; Braun, S; Britsch, M; Britton, T; Brodzicka, J; Brook, N H; Bursche, A; Buytaert, J; Cadeddu, S; Calabrese, R; Calvi, M; Calvo Gomez, M; Campana, P; Campora Perez, D; Capriotti, L; Carbone, A; Carboni, G; Cardinale, R; Cardini, A; Carniti, P; Carson, L; Carvalho Akiba, K; Casse, G; Cassina, L; Castillo Garcia, L; Cattaneo, M; Cauet, Ch; Cavallero, G; Cenci, R; Charles, M; Charpentier, Ph; Chefdeville, M; Chen, S; Cheung, S-F; Chiapolini, N; Chrzaszcz, M; Cid Vidal, X; Ciezarek, G; Clarke, P E L; Clemencic, M; Cliff, H V; Closier, J; Coco, V; Cogan, J; Cogneras, E; Cogoni, V; Cojocariu, L; Collazuol, G; Collins, P; Comerma-Montells, A; Contu, A; Cook, A; Coombes, M; Coquereau, S; Corti, G; Corvo, M; Couturier, B; Cowan, G A; Craik, D C; Crocombe, A; Cruz Torres, M; Cunliffe, S; Currie, R; D'Ambrosio, C; Dall'Occo, E; Dalseno, J; David, P N Y; Davis, A; De Bruyn, K; De Capua, S; De Cian, M; De Miranda, J M; De Paula, L; De Simone, P; Dean, C-T; Decamp, D; Deckenhoff, M; Del Buono, L; Déléage, N; Demmer, M; Derkach, D; Deschamps, O; Dettori, F; Dey, B; Di Canto, A; Di Ruscio, F; Dijkstra, H; Donleavy, S; Dordei, F; Dorigo, M; Dosil Suárez, A; Dossett, D; Dovbnya, A; Dreimanis, K; Dufour, L; Dujany, G; Dupertuis, F; Durante, P; Dzhelyadin, R; Dziurda, A; Dzyuba, A; Easo, S; Egede, U; Egorychev, V; Eidelman, S; Eisenhardt, S; Eitschberger, U; Ekelhof, R; Eklund, L; El Rifai, I; Elsasser, Ch; Ely, S; Esen, S; Evans, H M; Evans, T; Falabella, A; Färber, C; Farley, N; Farry, S; Fay, R; Ferguson, D; Fernandez Albor, V; Ferrari, F; Ferreira Rodrigues, F; Ferro-Luzzi, M; Filippov, S; Fiore, M; Fiorini, M; Firlej, M; Fitzpatrick, C; Fiutowski, T; Fohl, K; Fol, P; Fontana, M; Fontanelli, F; Forty, R; Francisco, O; Frank, M; Frei, C; Frosini, M; Fu, J; Furfaro, E; Gallas Torreira, A; Galli, D; Gallorini, S; Gambetta, S; Gandelman, M; Gandini, P; Gao, Y; García Pardiñas, J; Garra Tico, J; Garrido, L; Gascon, D; Gaspar, C; Gauld, R; Gavardi, L; Gazzoni, G; Geraci, A; Gerick, D; Gersabeck, E; Gersabeck, M; Gershon, T; Ghez, Ph; Gianelle, A; Gianì, S; Gibson, V; Girard, O G; Giubega, L; Gligorov, V V; Göbel, C; Golubkov, D; Golutvin, A; Gomes, A; Gotti, C; Grabalosa Gándara, M; Graciani Diaz, R; Granado Cardoso, L A; Graugés, E; Graverini, E; Graziani, G; Grecu, A; Greening, E; Gregson, S; Griffith, P; Grillo, L; Grünberg, O; Gui, B; Gushchin, E; Guz, Yu; Gys, T; Hadavizadeh, T; Hadjivasiliou, C; Haefeli, G; Haen, C; Haines, S C; Hall, S; Hamilton, B; Han, X; Hansmann-Menzemer, S; Harnew, N; Harnew, S T; Harrison, J; He, J; Head, T; Heijne, V; Hennessy, K; Henrard, P; Henry, L; Hernando Morata, J A; van Herwijnen, E; Heß, M; Hicheur, A; Hill, D; Hoballah, M; Hombach, C; Hulsbergen, W; Humair, T; Hussain, N; Hutchcroft, D; Hynds, D; Idzik, M; Ilten, P; Jacobsson, R; Jaeger, A; Jalocha, J; Jans, E; Jawahery, A; Jing, F; John, M; Johnson, D; Jones, C R; Joram, C; Jost, B; Jurik, N; Kandybei, S; Kanso, W; Karacson, M; Karbach, T M; Karodia, S; Kecke, M; Kelsey, M; Kenyon, I R; Kenzie, M; Ketel, T; Khanji, B; Khurewathanakul, C; Klaver, S; Klimaszewski, K; Kochebina, O; Kolpin, M; Komarov, I; Koopman, R F; Koppenburg, P; Kozeiha, M; Kravchuk, L; Kreplin, K; Kreps, M; Krocker, G; Krokovny, P; Kruse, F; Krzemien, W; Kucewicz, W; Kucharczyk, M; Kudryavtsev, V; Kuonen, A K; Kurek, K; Kvaratskheliya, T; Lacarrere, D; Lafferty, G; Lai, A; Lambert, D; Lanfranchi, G; Langenbruch, C; Langhans, B; Latham, T; Lazzeroni, C; Le Gac, R; van Leerdam, J; Lees, J-P; Lefèvre, R; Leflat, A; Lefrançois, J; Leroy, O; Lesiak, T; Leverington, B; Li, Y; Likhomanenko, T; Liles, M; Lindner, R; Linn, C; Lionetto, F; Liu, B; Liu, X; Loh, D; Longstaff, I; Lopes, J H; Lucchesi, D; Lucio Martinez, M; Luo, H; Lupato, A; Luppi, E; Lupton, O; Lusardi, N; Lusiani, A; Machefert, F; Maciuc, F; Maev, O; Maguire, K; Malde, S; Malinin, A; Manca, G; Mancinelli, G; Manning, P; Mapelli, A; Maratas, J; Marchand, J F; Marconi, U; Marin Benito, C; Marino, P; Marks, J; Martellotti, G; Martin, M; Martinelli, M; Martinez Santos, D; Martinez Vidal, F; Martins Tostes, D; Massafferri, A; Matev, R; Mathad, A; Mathe, Z; Matteuzzi, C; Mauri, A; Maurin, B; Mazurov, A; McCann, M; McCarthy, J; McNab, A; McNulty, R; Meadows, B; Meier, F; Meissner, M; Melnychuk, D; Merk, M; Milanes, D A; Minard, M-N; Mitzel, D S; Molina Rodriguez, J; Monroy, I A; Monteil, S; Morandin, M; Morawski, P; Mordà, A; Morello, M J; Moron, J; Morris, A B; Mountain, R; Muheim, F; Müller, J; Müller, K; Müller, V; Mussini, M; Muster, B; Naik, P; Nakada, T; Nandakumar, R; Nandi, A; Nasteva, I; Needham, M; Neri, N; Neubert, S; Neufeld, N; Neuner, M; Nguyen, A D; Nguyen, T D; Nguyen-Mau, C; Niess, V; Niet, R; Nikitin, N; Nikodem, T; Ninci, D; Novoselov, A; O'Hanlon, D P; Oblakowska-Mucha, A; Obraztsov, V; Ogilvy, S; Okhrimenko, O; Oldeman, R; Onderwater, C J G; Osorio Rodrigues, B; Otalora Goicochea, J M; Otto, A; Owen, P; Oyanguren, A; Palano, A; Palombo, F; Palutan, M; Panman, J; Papanestis, A; Pappagallo, M; Pappalardo, L L; Pappenheimer, C; Parkes, C; Passaleva, G; Patel, G D; Patel, M; Patrignani, C; Pearce, A; Pellegrino, A; Penso, G; Pepe Altarelli, M; Perazzini, S; Perret, P; Pescatore, L; Petridis, K; Petrolini, A; Petruzzo, M; Picatoste Olloqui, E; Pietrzyk, B; Pilař, T; Pinci, D; Pistone, A; Piucci, A; Playfer, S; Plo Casasus, M; Poikela, T; Polci, F; Poluektov, A; Polyakov, I; Polycarpo, E; Popov, A; Popov, D; Popovici, B; Potterat, C; Price, E; Price, J D; Prisciandaro, J; Pritchard, A; Prouve, C; Pugatch, V; Puig Navarro, A; Punzi, G; Qian, W; Quagliani, R; Rachwal, B; Rademacker, J H; Rama, M; Rangel, M S; Raniuk, I; Rauschmayr, N; Raven, G; Redi, F; Reichert, S; Reid, M M; Dos Reis, A C; Ricciardi, S; Richards, S; Rihl, M; Rinnert, K; Rives Molina, V; Robbe, P; Rodrigues, A B; Rodrigues, E; Rodriguez Lopez, J A; Rodriguez Perez, P; Roiser, S; Romanovsky, V; Romero Vidal, A; Ronayne, J W; Rotondo, M; Rouvinet, J; Ruf, T; Ruiz Valls, P; Saborido Silva, J J; Sagidova, N; Sail, P; Saitta, B; Salustino Guimaraes, V; Sanchez Mayordomo, C; Sanmartin Sedes, B; Santacesaria, R; Santamarina Rios, C; Santimaria, M; Santovetti, E; Sarti, A; Satriano, C; Satta, A; Saunders, D M; Savrina, D; Schiller, M; Schindler, H; Schlupp, M; Schmelling, M; Schmelzer, T; Schmidt, B; Schneider, O; Schopper, A; Schubiger, M; Schune, M-H; Schwemmer, R; Sciascia, B; Sciubba, A; Semennikov, A; Serra, N; Serrano, J; Sestini, L; Seyfert, P; Shapkin, M; Shapoval, I; Shcheglov, Y; Shears, T; Shekhtman, L; Shevchenko, V; Shires, A; Siddi, B G; Silva Coutinho, R; Simi, G; Sirendi, M; Skidmore, N; Skillicorn, I; Skwarnicki, T; Smith, E; Smith, E; Smith, I T; Smith, J; Smith, M; Snoek, H; Sokoloff, M D; Soler, F J P; Soomro, F; Souza, D; Souza De Paula, B; Spaan, B; Spradlin, P; Sridharan, S; Stagni, F; Stahl, M; Stahl, S; Stefkova, S; Steinkamp, O; Stenyakin, O; Stevenson, S; Stoica, S; Stone, S; Storaci, B; Stracka, S; Straticiuc, M; Straumann, U; Sun, L; Sutcliffe, W; Swientek, K; Swientek, S; Syropoulos, V; Szczekowski, M; Szczypka, P; Szumlak, T; T'Jampens, S; Tayduganov, A; Tekampe, T; Teklishyn, M; Tellarini, G; Teubert, F; Thomas, C; Thomas, E; van Tilburg, J; Tisserand, V; Tobin, M; Todd, J; Tolk, S; Tomassetti, L; Tonelli, D; Topp-Joergensen, S; Torr, N; Tournefier, E; Tourneur, S; Trabelsi, K; Tran, M T; Tresch, M; Trisovic, A; Tsaregorodtsev, A; Tsopelas, P; Tuning, N; Ukleja, A; Ustyuzhanin, A; Uwer, U; Vacca, C; Vagnoni, V; Valenti, G; Vallier, A; Vazquez Gomez, R; Vazquez Regueiro, P; Vázquez Sierra, C; Vecchi, S; Velthuis, J J; Veltri, M; Veneziano, G; Vesterinen, M; Viaud, B; Vieira, D; Vieites Diaz, M; Vilasis-Cardona, X; Vollhardt, A; Volyanskyy, D; Voong, D; Vorobyev, A; Vorobyev, V; Voß, C; de Vries, J A; Waldi, R; Wallace, C; Wallace, R; Walsh, J; Wandernoth, S; Wang, J; Ward, D R; Watson, N K; Websdale, D; Weiden, A; Whitehead, M; Wilkinson, G; Wilkinson, M; Williams, M; Williams, M P; Williams, M; Williams, T; Wilson, F F; Wimberley, J; Wishahi, J; Wislicki, W; Witek, M; Wormser, G; Wotton, S A; Wright, S; Wyllie, K; Xie, Y; Xu, Z; Yang, Z; Yu, J; Yuan, X; Yushchenko, O; Zangoli, M; Zavertyaev, M; Zhang, L; Zhang, Y; Zhelezov, A; Zhokhov, A; Zhong, L; Zucchelli, S

    2015-08-14

    Observations of exotic structures in the J/ψp channel, which we refer to as charmonium-pentaquark states, in Λ_{b}^{0}→J/ψK^{-}p decays are presented. The data sample corresponds to an integrated luminosity of 3 fb^{-1} acquired with the LHCb detector from 7 and 8 TeV pp collisions. An amplitude analysis of the three-body final state reproduces the two-body mass and angular distributions. To obtain a satisfactory fit of the structures seen in the J/ψp mass spectrum, it is necessary to include two Breit-Wigner amplitudes that each describe a resonant state. The significance of each of these resonances is more than 9 standard deviations. One has a mass of 4380±8±29 MeV and a width of 205±18±86 MeV, while the second is narrower, with a mass of 4449.8±1.7±2.5 MeV and a width of 39±5±19 MeV. The preferred J^{P} assignments are of opposite parity, with one state having spin 3/2 and the other 5/2.

  1. Observation of a peaking structure in the $$J/\\psi \\phi$$ mass spectrum from $$B^{\\pm} \\to J/\\psi \\phi K^{\\pm}$$ decays

    DOE PAGES

    Chatrchyan, Serguei

    2014-05-22

    A peaking structure in the J/psi phi mass spectrum near threshold is observed in B(+/-) to J/psi phi K(+/-) decays, produced in pp collisions at sqrt(s) = 7 TeV collected with the CMS detector at the LHC. The data sample, selected on the basis of the dimuon decay mode of the J/psi, corresponds to an integrated luminosity of 5.2 inverse femtobarns. Fitting the structure to an S-wave relativistic Breit-Wigner lineshape above a three-body phase-space nonresonant component gives a signal statistical significance exceeding five standard deviations. The fitted mass and width values are m = 4148.0 +- 2.4 (stat.) +- 6.3more » (syst.) MeV and Gamma = 28 +15 -11 (stat.) +- 19 (syst.) MeV, respectively. Evidence for an additional peaking structure at higher J/psi phi mass is also reported.« less

  2. Study of the B + c → J/ΨD + s and B + c → J/ΨD* s + decays with the ATLAS detector

    DOE PAGES

    Aad, G.; Abbott, B.; Abdallah, J.; ...

    2016-01-05

    The decays B + c → J/ΨD + s and B + c → J/ΨD* s + are studied with the ATLAS detector at the LHC using a dataset corresponding to integrated luminosities of 4.9 and 20.6 fb –1 of pp collisions collected at centre-of-mass energies √s = 7 TeV and 8 TeV, respectively. Furthermore, signal candidates are identified through J/ψ → μ +μ - and D (*)+ s → Φπ +(γ/π 0) decays.

  3. Al-Bitrūjī's theory of the motions of the fixed stars

    NASA Astrophysics Data System (ADS)

    Mancha, J. L.

    2004-01-01

    The problem which this paper deals with is the following: were the homocentric models of Eudoxus alluded to by Aristotle (Metaphysics, xii.8) preserved in al-Bitrūjī's Kitab fi'l-hay'a, as argued by Kennedy in his reviews of Carmody's edition of Scot's Latin version and Goldstein's English translation based on the Arabic and Hebrew versions of the work - or, as asserted by Goldstein, was the essence of al-Bitrūjī's reform to place Ptolemaic models on the surface of a sphere, influenced by the tradition of the trepidation theory and especially by Ibn al-Zarqallu's contributions, without knowledge whatever of Eudoxus? To answer this question, this paper presents an analysis and new translation of the second chapter of al-Bitrūjī's work, devoted to the motion of the stars, based on the two extant Latin versions. From them it follows that the model described in this chapter is indeed a Eudoxan couple, whose hippopede accounts for the motions of the stars: in al-Bitrūjī's words, a true motion in declination and another, merely apparent, in accession and recession.

  4. Forward J /ψ and very backward jet inclusive production at the LHC

    NASA Astrophysics Data System (ADS)

    Boussarie, R.; Ducloué, B.; Szymanowski, L.; Wallon, S.

    2018-01-01

    In the spirit of Mueller-Navelet dijet production, we propose and study the inclusive production of a forward J /ψ and a very backward jet at the LHC as an observable to reveal high-energy resummation effects à la Balitsky, Fadin, Kuraev, Lipatov. We obtain several predictions, which are based on the various mechanisms discussed in the literature to describe the production of the J /ψ , namely, nonrelativistic QCD singlet and octet contributions, and the color evaporation model.

  5. Structural Basis of J Cochaperone Binding and Regulation of Hsp70

    PubMed Central

    Jiang, Jianwen; Maes, E. Guy; Taylor, Alex B; Wang, Liping; Hinck, Andrew P; Lafer, Eileen M; Sousa, Rui

    2007-01-01

    The many protein processing reactions of the ATP-hydrolyzing Hsp70s are regulated by J cochaperones, which contain J domains that stimulate Hsp70 ATPase activity and accessory domains that present protein substrates to Hsp70s. We report the structure of a J domain complexed with a J responsive portion of a mammalian Hsp70. The J domain activates ATPase activity by directing the linker that connects the Hsp70 nucleotide binding domain (NBD) and substrate binding domain (SBD) towards a hydrophobic patch on the NBD surface. Binding of the J domain to Hsp70 displaces the SBD from the NBD, which may allow the SBD flexibility to capture diverse substrates. Unlike prokaryotic Hsp70, the SBD and NBD of the mammalian chaperone interact in the ADP state. Thus, while both nucleotides and J cochaperones modulate Hsp70 NBD:linker and NBD:SBD interactions, the intrinsic persistence of those interactions differs in different Hsp70s and this may optimize their activities for different cellular roles. PMID:17996706

  6. Enhancing SAMOS Data Access in DOMS via a Neo4j Property Graph Database.

    NASA Astrophysics Data System (ADS)

    Stallard, A. P.; Smith, S. R.; Elya, J. L.

    2016-12-01

    The Shipboard Automated Meteorological and Oceanographic System (SAMOS) initiative provides routine access to high-quality marine meteorological and near-surface oceanographic observations from research vessels. The Distributed Oceanographic Match-Up Service (DOMS) under development is a centralized service that allows researchers to easily match in situ and satellite oceanographic data from distributed sources to facilitate satellite calibration, validation, and retrieval algorithm development. The service currently uses Apache Solr as a backend search engine on each node in the distributed network. While Solr is a high-performance solution that facilitates creation and maintenance of indexed data, it is limited in the sense that its schema is fixed. The property graph model escapes this limitation by creating relationships between data objects. The authors will present the development of the SAMOS Neo4j property graph database including new search possibilities that take advantage of the property graph model, performance comparisons with Apache Solr, and a vision for graph databases as a storage tool for oceanographic data. The integration of the SAMOS Neo4j graph into DOMS will also be described. Currently, Neo4j contains spatial and temporal records from SAMOS which are modeled into a time tree and r-tree using Graph Aware and Spatial plugin tools for Neo4j. These extensions provide callable Java procedures within CYPHER (Neo4j's query language) that generate in-graph structures. Once generated, these structures can be queried using procedures from these libraries, or directly via CYPHER statements. Neo4j excels at performing relationship and path-based queries, which challenge relational-SQL databases because they require memory intensive joins due to the limitation of their design. Consider a user who wants to find records over several years, but only for specific months. If a traditional database only stores timestamps, this type of query would be complex

  7. Evolution of an intricate J-protein network driving protein disaggregation in eukaryotes.

    PubMed

    Nillegoda, Nadinath B; Stank, Antonia; Malinverni, Duccio; Alberts, Niels; Szlachcic, Anna; Barducci, Alessandro; De Los Rios, Paolo; Wade, Rebecca C; Bukau, Bernd

    2017-05-15

    Hsp70 participates in a broad spectrum of protein folding processes extending from nascent chain folding to protein disaggregation. This versatility in function is achieved through a diverse family of J-protein cochaperones that select substrates for Hsp70. Substrate selection is further tuned by transient complexation between different classes of J-proteins, which expands the range of protein aggregates targeted by metazoan Hsp70 for disaggregation. We assessed the prevalence and evolutionary conservation of J-protein complexation and cooperation in disaggregation. We find the emergence of a eukaryote-specific signature for interclass complexation of canonical J-proteins. Consistently, complexes exist in yeast and human cells, but not in bacteria, and correlate with cooperative action in disaggregation in vitro. Signature alterations exclude some J-proteins from networking, which ensures correct J-protein pairing, functional network integrity and J-protein specialization. This fundamental change in J-protein biology during the prokaryote-to-eukaryote transition allows for increased fine-tuning and broadening of Hsp70 function in eukaryotes.

  8. J-SHIS - an integrated system for knowing seismic hazard information in Japan

    NASA Astrophysics Data System (ADS)

    Azuma, H.; Fujiwara, H.; Kawai, S.; Hao, K. X.; Morikawa, N.

    2015-12-01

    An integrated system of Japan seismic hazard information station (J-SHIS) was established in 2005 for issuing and exchanging information of the National Seismic Hazard Maps for Japan that are based on seismic hazard assessment (SHA). A simplified app, also named J-SHIS, for smartphones is popularly used in Japan based on the integrated system of http://www.j-shis.bosai.go.jp/map/?lang=en. "Smartphone tells hazard" is realized on a cellphone, a tablet and/or a PC. At a given spot, the comprehensive information of SHA map can be easily obtained as below: 1) A SHA probability at given intensity (JMA=5-, 5+, 6-, 6+) within 30 years. 2) A site amplification factor varies within 0.5 ~ 3.0 and expectation is 1 based on surface geology map information. 3) A depth of seismic basement down to ~3,000m based on deeper borehole and geological structure. 4) Scenario earthquake maps: By choosing an active fault, one got the average case for different parameters of the modeling. Then choose a case, you got the shaking map of intensity with color scale. "Seismic Hazard Karte tells more hazard" is another app based on website of http://www.j-shis.bosai.go.jp/labs/karte/. (1) For every mesh of 250m x 250m, professional service SHA information is provided over national-world. (2) With five ranks for eight items, comprehensive SHA information could be delivered. (3) Site amplification factor with an average index is given. (4) Deeper geologic structure modeling is provided with borehole profiling. (5) A SHA probability is assessed within 30 and/or 50 years for the given site. (6) Seismic Hazard curves are given for earthquake sources from inland active fault, subduction zone, undetermined and their summarization. (7) The JMA seismic intensities are assessed in long-term averaged periods of 500-years to ~100,000 years. The app of J-SHIS can be downloaded freely from http://www.j-shis.bosai.go.jp/app-jshis.

  9. Ileal J-pouch vaginoplasty: reconstruction of a physiologic vagina with an ileal J-pouch.

    PubMed

    Schneider, Wolfgang; Nguyen-Thanh, Phuong; Dralle, Henning; Mirastschijski, Ursula

    2009-06-01

    Vaginal reconstruction has been performed for more than a century. Main complications are vaginal stenosis requiring dilatation, dyspareunia, excessive mucus secretion, and poor aesthetic and functional outcome. Here we report a new operation method modified after Baldwin for intestinal vaginoplasty in a patient with pelvic exenteration after spinal cell carcinoma of the vagina. Because of balanced liquid resorption and mucus secretion with sufficient vessel length in the terminal ileum, this intestinal segment was chosen. A J-pouch of distal ileum was constructed pedicled on the ileocolic artery and accompanying nervous plexus, transferred into the lower pelvis and sutured to the vaginal stump. One year follow-up showed a highly satisfied, sexually active patient, with adequate vaginal size, optimal lubrication and no molesting fecal odor. Terminal ileum J-pouch vaginoplasty is an optimal method for vaginal reconstruction providing a sufficient vaginal lumen and lubrication and thereby restoring patients' sexual life and increasing life quality.

  10. Discrete contribution to {psi}{sup '}{yields}J/{psi}+{gamma}{gamma}

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    He Zhiguo; Soto, Joan; Lu Xiaorui

    2011-03-01

    The decay mode {psi}(2S){yields}J/{psi}+{gamma}{gamma} is proposed in order to experimentally identify the effects of the coupling of charmonium states to the continuum D{bar D} states. To have a better understanding of such a two-photon decay process, in this work we restrict ourselves to investigate the contribution of the discrete part, in which the photons are mainly produced via the intermediate states {chi}{sub cJ}(nP). Besides calculating the resonance contributions of {chi}{sub cJ}(1P)(J=0,1,2), we also take into account the contributions of the higher excited states {chi}{sub cJ}(2P) and the interference effect among the 1P and 2P states. We find that the contributionmore » of the 2P states and the interference terms to the total decay width is very tiny. However, for specific regions of the Dalitz plot, off the resonance peaks, we find that these contributions are sizable and should also be accounted for. We also provide the photon spectrum and study the polarization of J/{psi}.« less

  11. Thermal Effect of J-Plasma® Energy in a Porcine Tissue Model: Implications for Minimally Invasive Surgery.

    PubMed

    Pedroso, Jasmine D; Gutierrez, Melissa M; Volker, K Warren; Howard, David L

    2017-07-25

    To evaluate tissue effect of J-Plasma® (Bovie Medical Corporation, Clearwater, Florida) in porcine liver, kidney, muscle, ovarian, and uterine tissue blocks. Prospective study utilizing porcine tissue blocks to evaluate the thermal spread of J-Plasma® device on liver, kidney, muscle, ovarian, and uterine tissue at various power settings, gas flow, and exposure times. J-Plasma® helium was used in porcine liver, kidney, and muscle tissue at 20%, 50%, and 100% power, and 1 L/min, 3 L/min, and 5 L/min gas flow at one, five, and 10-second intervals. J-Plasma® was then used in ovarian and uterine tissue at maximum power and gas flow settings in intervals of one, five, 10, and 30 seconds. Histologic evaluation of each tissue was then performed to measure thermal spread. Regardless of tissue type, increased power setting, gas flow rate, and exposure time correlated with greater depth of thermal spread in liver, kidney, and muscle tissue. J-Plasma® did not exceed 2 mm thermal spread on liver, kidney, muscle, ovarian, and uterine tissue, even at a maximum setting of 100% power and 5 L/min gas flow after five seconds. Prolonged exposure to J-Plasma® of up to 30 seconds resulted in increased length and width of thermal spread of up to 12 mm, but did not result in significantly increased depth at 2.84 mm. The J-Plasma® helium device has minimal lateral and depth of thermal spread in a variety of tissue types and can likely be used for a multitude of gynecologic surgical procedures. However, further studies are needed to demonstrate device safety in a clinical setting.

  12. National Contingency Plan Subpart J

    EPA Pesticide Factsheets

    Subpart J of the National Oil and Hazardous Substances Pollution Contingency Plan (NCP) directs EPA to prepare a schedule of dispersants, other chemicals, and oil spill mitigating devices and substances that may be used to remove or control oil discharges.

  13. Notification: Northwest Indian Fisheries Commission’s Puget Sound Protection and Restoration Implementation cooperative agreements PA00J32201 and PA00J91201

    EPA Pesticide Factsheets

    May 27, 2016. The EPA OIG plans to begin preliminary research on the Northwest Indian Fisheries Commission’s (NWIFC’s) Puget Sound Protection and Restoration Implementation cooperative agreements PA00J32201 and PA00J91201.

  14. Single-hole spectral function and spin-charge separation in the t-J model

    NASA Astrophysics Data System (ADS)

    Mishchenko, A. S.; Prokof'ev, N. V.; Svistunov, B. V.

    2001-07-01

    Worm algorithm Monte Carlo simulations of the hole Green function with subsequent spectral analysis were performed for 0.1<=J/t<=0.4 on lattices with up to L×L=32×32 sites at a temperature as low as T=J/40, and present, apparently, the hole spectral function in the thermodynamic limit. Spectral analysis reveals a δ-function-sharp quasiparticle peak at the lower edge of the spectrum that is incompatible with the power-law singularity and thus rules out the possibility of spin-charge separation in this parameter range. Spectral continuum features two peaks separated by a gap ~4÷5 t.

  15. Potential applicability of chymotrypsin-susceptible microcin J25 derivatives to food preservation.

    PubMed

    Pomares, María Fernanda; Salomón, Raúl A; Pavlova, Olga; Severinov, Konstantin; Farías, Ricardo; Vincent, Paula A

    2009-09-01

    Microcin J25 (MccJ25) is a 21-residue ribosomally synthesized lariat peptide antibiotic. MccJ25 is active against such food-borne disease-causing pathogens as Salmonella spp., Shigella spp., and Escherichia coli, including E. coli O157:H7 and non-O157 strains. MccJ25 is highly resistant to digestion by proteolytic enzymes present in the stomach and intestinal contents. MccJ25 would therefore remain active in the gastrointestinal tract, affecting normal intestinal microbiota, and this limits the potential use of MccJ25 as a food preservative. In the present paper, we describe a chymotrypsin-susceptible MccJ25 derivative with a mutation of Gly(12) to Tyr that retained almost full antibiotic activity and efficiently inhibited the growth of pathogenic Salmonella enterica serovar Newport and Escherichia coli O157:H7 in skim milk and egg yolk. However, unlike the wild-type MccJ25, the MccJ25(G12Y) variant was inactivated by digestive enzymes both in vitro and in vivo. To our knowledge, our results represent the first example of a rational modification of a microcin aimed at increasing its potential use in food preservation.

  16. Maternal choline modifies fetal liver copper, gene expression, DNA methylation, and neonatal growth in the tx-j mouse model of Wilson disease.

    PubMed

    Medici, Valentina; Shibata, Noreene M; Kharbanda, Kusum K; Islam, Mohammad S; Keen, Carl L; Kim, Kyoungmi; Tillman, Brittany; French, Samuel W; Halsted, Charles H; LaSalle, Janine M

    2014-02-01

    Maternal diet can affect fetal gene expression through epigenetic mechanisms. Wilson disease (WD), which is caused by autosomal recessive mutations in ATP7B encoding a biliary copper transporter, is characterized by excessive hepatic copper accumulation, but variability in disease severity. We tested the hypothesis that gestational supply of dietary methyl groups modifies fetal DNA methylation and expression of genes involved in methionine and lipid metabolism that are impaired prior to hepatic steatosis in the toxic milk (tx-j) mouse model of WD. Female C3H control and tx-j mice were fed control (choline 8 mmol/Kg of diet) or choline-supplemented (choline 36 mmol/Kg of diet) diets for 2 weeks throughout mating and pregnancy to gestation day 17. A second group of C3H females, half of which were used to cross foster tx-j pups, received the same diet treatments that extended during lactation to 21 d postpartum. Compared with C3H, fetal tx-j livers had significantly lower copper concentrations and significantly lower transcript levels of Cyclin D1 and genes related to methionine and lipid metabolism. Maternal choline supplementation prevented the transcriptional deficits in fetal tx-j liver for multiple genes related to cell growth and metabolism. Global DNA methylation was increased by 17% in tx-j fetal livers after maternal choline treatment (P<0.05). Maternal dietary choline rescued the lower body weight of 21 d tx-j mice. Our results suggest that WD pathogenesis is modified by maternal in utero factors, including dietary choline.

  17. Maternal choline modifies fetal liver copper, gene expression, DNA methylation, and neonatal growth in the tx-j mouse model of Wilson disease

    PubMed Central

    Medici, Valentina; Shibata, Noreene M; Kharbanda, Kusum K; Islam, Mohammad S; Keen, Carl L; Kim, Kyoungmi; Tillman, Brittany; French, Samuel W; Halsted, Charles H; LaSalle, Janine M

    2014-01-01

    Maternal diet can affect fetal gene expression through epigenetic mechanisms. Wilson disease (WD), which is caused by autosomal recessive mutations in ATP7B encoding a biliary copper transporter, is characterized by excessive hepatic copper accumulation, but variability in disease severity. We tested the hypothesis that gestational supply of dietary methyl groups modifies fetal DNA methylation and expression of genes involved in methionine and lipid metabolism that are impaired prior to hepatic steatosis in the toxic milk (tx-j) mouse model of WD. Female C3H control and tx-j mice were fed control (choline 8 mmol/Kg of diet) or choline-supplemented (choline 36 mmol/Kg of diet) diets for 2 weeks throughout mating and pregnancy to gestation day 17. A second group of C3H females, half of which were used to cross foster tx-j pups, received the same diet treatments that extended during lactation to 21 d postpartum. Compared with C3H, fetal tx-j livers had significantly lower copper concentrations and significantly lower transcript levels of Cyclin D1 and genes related to methionine and lipid metabolism. Maternal choline supplementation prevented the transcriptional deficits in fetal tx-j liver for multiple genes related to cell growth and metabolism. Global DNA methylation was increased by 17% in tx-j fetal livers after maternal choline treatment (P < 0.05). Maternal dietary choline rescued the lower body weight of 21 d tx-j mice. Our results suggest that WD pathogenesis is modified by maternal in utero factors, including dietary choline. PMID:24220304

  18. J-2X Powerpack hot-fire test

    NASA Image and Video Library

    2008-01-31

    The first hot-fire test of the J-2X power pack 1A gas generator was performed Jan. 31 on the A-1 Test Stand at Stennis Space Center. Initial indications are that all test objectives were met. The test was designed as a 3.42-second helium spin start with gas generator ignition and it went the full scheduled duration. Test conductors reported a smooth start with normal shutdown and described the event as a 'good test.' The test was part of the early component testing for the new J-2X engine being built by NASA to power the Ares I and Ares V rockets that will carry humans back to the moon and on to Mars. It was performed as one in a series of 12 scheduled tests. Those tests began last November at Stennis, but the January 31 event represented the first hot-fire test. The Stennis tests are a critical step in the successful development of the J-2X engine.

  19. Psr J2030+3641: Radio Discovery And Gamma-Ray Study Of A Middle-Aged Pulsar In The Now Identified Fermi -Lat Source 1FGL J2030.0+3641

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Camilo, F.; Kerr, M.; Ray, P. S.

    2012-01-23

    In a radio search with the Green Bank Telescope of three unidentified low Galactic latitude Fermi-LAT sources, we have discovered the middle-aged pulsar J2030+3641, associated with 1FGL J2030.0+3641 (2FGL J2030.0+3640). Following the detection of gamma-ray pulsations using a radio ephemeris, we have obtained a phase-coherent timing solution based on gamma-ray and radio pulse arrival times that spans the entire Fermi mission. With a rotation period of 0.2 s, spin-down luminosity of 3X10 34 erg s -1, and characteristic age of 0.5 Myr, PSR J2030+3641 is a middle-aged neutron star with spin parameters similar to those of the exceedingly gamma-ray-bright andmore » radio-undetected Geminga. Its gamma-ray flux is 1% that of Geminga, primarily because of its much larger distance, as suggested by the large integrated column density of free electrons, DM = 246 pc cm-3. We fit the gamma-ray light curve, along with limited radio polarimetric constraints, to four geometrical models of magnetospheric emission, and while none of the fits have high significance some are encouraging and suggest that further refinements of these models may be worthwhile. We argue that not many more non-millisecond radio pulsars may be detected along the Galactic plane that are responsible for LAT sources, but that modified methods to search for gamma-ray pulsations should be productive — PSR J2030+3641 would have been found blindly in gamma rays if only & 0:8 GeV photons had been considered, owing to its relatively flat spectrum and location in a region of high soft background.« less

  20. PSR J2030+364I: Radio Discovery and Gamma-ray Study of a Middle-aged Pulsar in the Now Identified Fermi-LAT Source 1FGL J2030.0+3641

    NASA Technical Reports Server (NTRS)

    Camilo, F.; Kerr, M.; Ray, P. S.; Ransom, S. M.; Johnston, S.; Romani, R. W.; Parent, D.; Decesar, M. E.; Harding, A. K.; Donato, D.; hide

    2011-01-01

    In a radio search with the Green Bank Telescope of three unidentified low Galactic latitude Fermi-LAT sources, we have discovered the middle-aged pulsar J2030+3641, associated with IFGL J2030.0+3641 (2FGL J2030.0+3640). Following the detection of gamma-ray pulsations using a radio ephemeris, we have obtained a phase-coherent timing solution based on gamma-ray and radio pulse arrival times that spans the entire Fermi mission. With a rotation period of 0.28, spin-down luminosity of 3 x 10(exp 34) erg/s, and characteristic age of 0.5 Myr, PSR J2030+3641 is a middle-aged neutron star with spin parameters similar to those of the exceedingly gamma-ray-bright and radio-undetected Geminga. Its gamma-ray flux is 1 % that of Geminga, primarily because of its much larger distance, as suggested by the large integrated column density of free electrons, DM = 246 pc/cu cm. We fit the gamma-ray light curve, along with limited radio polarimetric constraints, to four geometrical models of magnetospheric emission, and while none of the fits have high significance some are encouraging and suggest that further refinements of these models may be worthwhile. We argue that not many more non-millisecond radio pulsars may be detected along the Galactic plane that are responsible for LAT sources, but that modified methods to search for gamma-ray pulsations should be productive - PSR J2030+364 I would have been found blindly in gamma rays if only > or approx. 0.8 GeV photons had been considered, owing to its relatively flat spectrum and location in a region of high soft background.

  1. Precise gene editing of chicken Na+/H+ exchange type 1 (chNHE1) confers resistance to avian leukosis virus subgroup J (ALV-J).

    PubMed

    Lee, Hong Jo; Lee, Kyung Youn; Jung, Kyung Min; Park, Kyung Je; Lee, Ko On; Suh, Jeong-Yong; Yao, Yongxiu; Nair, Venugopal; Han, Jae Yong

    2017-12-01

    Avian leukosis virus subgroup J (ALV-J), first isolated in the late 1980s, has caused economic losses to the poultry industry in many countries. As all chicken lines studied to date are susceptible to ALV infection, there is enormous interest in developing resistant chicken lines. The ALV-J receptor, chicken Na + /H + exchange 1 (chNHE1) and the critical amino acid sequences involved in viral attachment and entry have already been characterized. However, there are no reported attempts to induce resistance to the virus by targeted genome modification of the receptor sequences. In an attempt to induce resistance to ALV-J infection, we used clustered regularly interspaced short palindromic repeats (CRISPR)-associated (CRISPR/Cas9)-based genome editing approaches to modify critical residues of the chNHE1 receptor in chicken cells. The susceptibility of the modified cell lines to ALV-J infection was examined using enhanced green fluorescent protein (EGFP)-expressing marker viruses. We showed that modifying the chNHE1 receptor by artificially generating a premature stop codon induced absolute resistance to viral infection, with mutations of the tryptophan residue at position 38 (Trp38) being very critical. Single-stranded oligodeoxynucleotide (ssODN)-mediated targeted recombination of the Trp38 region revealed that deletions involving the Trp38 residue were most effective in conferring resistance to ALV-J. Moreover, protein structure analysis of the chNHE1 receptor sequence suggested that its intrinsically disordered region undergoes local conformational changes through genetic alteration. Collectively, these results demonstrate that targeted mutations on chNHE1 alter the susceptibility to ALV-J and the technique is expected to contribute to develop disease-resistant chicken lines. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. Baicalin is an inhibitor of subgroup J avian leukosis virus infection.

    PubMed

    Qian, Kun; Kong, Zheng-Ru; Zhang, Jie; Cheng, Xiao-Wei; Wu, Zong-Yi; Gu, Cheng-Xi; Shao, Hong-Xia; Qin, Ai-Jian

    2018-03-15

    Avian leukosis virus subgroup J (ALV-J) can cause great economic losses to the poultry industry worldwide. Baicalin, one of the flavonoids present in S.baicalensis Georgi, has been shown to have antiviral activities. To investigate whether baicalin has antiviral effects on the infection of ALV-J in DF-1 cells, the cells were treated with baicalin at different time points. We found that baicalin could inhibit viral mRNA, protein levels and overall virus infection in a dose- and time-dependent manner using a variety of assays. Baicalin specifically targeted virus internalization and reduced the infectivity of ALV-J particles, but had no effect on the levels of major ALV-J receptor and virus binding to DF-1 cells. Collectively, these results suggest that baicalin might have potential to be developed as a novel antiviral agent for ALV-J infection. Copyright © 2018 Elsevier B.V. All rights reserved.

  3. Revisiting the Gamma-Ray Source 2FGL J1823.8+4312

    NASA Astrophysics Data System (ADS)

    Stern, Daniel; Assef, Roberto J.

    2013-02-01

    One of the great challenges of gamma-ray astronomy is identifying the lower energy counterparts to these high-energy sources. Recently, in this journal, Massaro et al. attempted to find the counterpart of 2FGL J1823.8+4312, a gamma-ray active galactic nucleus (AGN) of uncertain type from the Second Fermi Large Area Telescope catalog. After considering mid-infrared data in the field from the Wide-field Infrared Survey Explorer (WISE), those authors conclude that the preferred identification of 2FGL J1823.8+4312 is WISE J182352.33+431452.5, despite the fact that the mid-infrared source is undetected at radio energies. They claim that WISE J182352.33+431452.5 constitutes the discovery of a new class of extragalactic X-ray source, either a radio-faint blazar or the prototype of a new class of active galaxy with an enigmatic spectral energy distribution. This conclusion is claimed to be independent of whether or not the WISE source is the actual counterpart to 2FGL J1823.8+4312. Based on a re-analysis of public data in this field and new spectroscopy from Palomar, we conclude that WISE J182352.33+431452.5 is a dust-reddened quasar at z = 0.560, a representative example of a very common extragalactic AGN class. Were WISE J182352.33+431452.5 to be associated with the gamma-ray emission, this would be an unusual and exciting discovery. However, we argue that 2FGL J1823.8+4312 is more likely associated with either WISE J182409.25+431404.7 or, more likely, WISE J182419.04+430949.6, two radio-loud sources in the field. The former is a radio-loud quasar and the latter is an optically variable source with a featureless blue spectrum.

  4. Measurement of the CP-violating phase β s J/ψΦ in B s 0→J/ψΦ decays with the CDF II detector

    DOE PAGES

    Aaltonen, T.; Álvarez González, B.; Amerio, S.; ...

    2012-04-23

    We present a measurement of the CP-violating parameter β s J/ψΦ using approximately 6500 B 0 s→J/ψΦ decays reconstructed with the CDF II detector in a sample of pp̄ collisions at √s=1.96 TeV corresponding to 5.2 fb⁻¹ integrated luminosity produced by the Tevatron collider at Fermilab. We find the CP-violating phase to be within the range β s J/ψΦϵ [0.02,0.52]∪[1.08,1.55] at 68% confidence level where the coverage property of the quoted interval is guaranteed using a frequentist statistical analysis. This result is in agreement with the standard model expectation at the level of about one Gaussian standard deviation. We considermore » the inclusion of a potential S-wave contribution to the B 0 s→J/ψK⁺K⁻ final state which is found to be negligible over the mass interval 1.009s J/ψΦ, we find the B 0 s decay width difference to be ΔΓ s=0.075±0.035(stat)±0.006(syst) ps⁻¹. We also present the most precise measurements of the B 0 s mean lifetime τ(B 0 s)=1.529±0.025(stat)±0.012(syst) ps, the polarization fractions |A0(0)|²=0.524±0.013(stat)±0.015(syst) and |A II (0)|²=0.231±0.014(stat)±0.015(syst), as well as the strong phase δ ⊥=2.95±0.64(stat)±0.07(syst) rad. In addition, we report an alternative Bayesian analysis that gives results consistent with the frequentist approach.« less

  5. Overexpression of SepJ alters septal morphology and heterocyst pattern regulated by diffusible signals in Anabaena.

    PubMed

    Mariscal, Vicente; Nürnberg, Dennis J; Herrero, Antonia; Mullineaux, Conrad W; Flores, Enrique

    2016-09-01

    Filamentous, N2 -fixing, heterocyst-forming cyanobacteria grow as chains of cells that are connected by septal junctions. In the model organism Anabaena sp. strain PCC 7120, the septal protein SepJ is required for filament integrity, normal intercellular molecular exchange, heterocyst differentiation, and diazotrophic growth. An Anabaena strain overexpressing SepJ made wider septa between vegetative cells than the wild type, which correlated with a more spread location of SepJ in the septa as observed with a SepJ-GFP fusion, and contained an increased number of nanopores, the septal peptidoglycan perforations that likely accommodate septal junctions. The septa between heterocysts and vegetative cells, which are narrow in wild-type Anabaena, were notably enlarged in the SepJ-overexpressing mutant. Intercellular molecular exchange tested with fluorescent tracers was increased for the SepJ-overexpressing strain specifically in the case of calcein transfer between vegetative cells and heterocysts. These results support an association between calcein transfer, SepJ-related septal junctions, and septal peptidoglycan nanopores. Under nitrogen deprivation, the SepJ-overexpressing strain produced an increased number of contiguous heterocysts but a decreased percentage of total heterocysts. These effects were lost or altered in patS and hetN mutant backgrounds, supporting a role of SepJ in the intercellular transfer of regulatory signals for heterocyst differentiation. © 2016 John Wiley & Sons Ltd.

  6. The J-2X Fuel Turbopump - Design, Development, and Test

    NASA Technical Reports Server (NTRS)

    Tellier, James G.; Hawkins, Lakiesha V.; Shinguchi, Brian H.; Marsh, Matthew W.

    2011-01-01

    Pratt and Whitney Rocketdyne (PWR), a NASA subcontractor, is executing the design, development, test, and evaluation (DDT&E) of a liquid oxygen, liquid hydrogen two hundred ninety four thousand pound thrust rocket engine initially intended for the Upper Stage (US) and Earth Departure Stage (EDS) of the Constellation Program Ares-I Crew Launch Vehicle (CLV). A key element of the design approach was to base the new J-2X engine on the heritage J-2S engine with the intent of uprating the engine and incorporating SSME and RS-68 lessons learned. The J-2S engine was a design upgrade of the flight proven J-2 configuration used to put American astronauts on the moon. The J-2S Fuel Turbopump (FTP) was the first Rocketdyne-designed liquid hydrogen centrifugal pump and provided many of the early lessons learned for the Space Shuttle Main Engine High Pressure Fuel Turbopumps. This paper will discuss the design trades and analyses performed for the current J-2X FTP to increase turbine life; increase structural margins, facilitate component fabrication; expedite turbopump assembly; and increase rotordynamic stability margins. Risk mitigation tests including inducer water tests, whirligig turbine blade tests, turbine air rig tests, and workhorse gas generator tests characterized operating environments, drove design modifications, or identified performance impact. Engineering design, fabrication, analysis, and assembly activities support FTP readiness for the first J-2X engine test scheduled for July 2011.

  7. Parallel performance of TORT on the CRAY J90: Model and measurement

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Barnett, A.; Azmy, Y.Y.

    1997-10-01

    A limitation on the parallel performance of TORT on the CRAY J90 is the amount of extra work introduced by the multitasking algorithm itself. The extra work beyond that of the serial version of the code, called overhead, arises from the synchronization of the parallel tasks and the accumulation of results by the master task. The goal of recent updates to TORT was to reduce the time consumed by these activities. To help understand which components of the multitasking algorithm contribute significantly to the overhead, a parallel performance model was constructed and compared to measurements of actual timings of themore » code.« less

  8. Membrane lipid composition of pancreatic AR42J cells: modification by exposure to different fatty acids.

    PubMed

    Audi, Nama'a; Mesa, María D; Martínez, María A; Martínez-Victoria, Emilio; Mañas, Mariano; Yago, María D

    2007-04-01

    Dietary fat type influences fatty acids in rat pancreatic membranes, in association with modulation of secretory activity and cell signalling in viable acini. We aimed to confirm whether AR42J cells are a valid model to study the interactions between lipids and pancreatic acinar cell function. For this purpose we have (i) compared the baseline fatty acid composition of AR42J cells with that of pancreatic membranes from rats fed a standard chow; (ii) investigated if fatty acids in AR42J membranes can be modified in culture; and (iii) studied if similar compositional variations that can be evoked in rats when dietary fat type is altered occur in AR42J cells. Weaning Wistar rats were fed for 8 weeks either a commercial chow (C) or semi-purified diets containing virgin olive oil (VOO) or sunflower oil (SO) as fat source. AR42J cells were incubated for 72 hrs in medium containing unmodified fetal calf serum (FCS, AR42J-C cells), FCS enriched with 18:1 n-9 (AR42J-O cells), or FCS enriched with 18:2 n-6 (AR42J-L cells). Fatty acids in crude membranes from rat pancreas and AR42J cells were determined by gas-liquid chromatography. Differences in membrane fatty acids between C rats and AR42J-C cells can be explained in part by variations in the amount of fatty acids in the extracellular environment. Supplementation of FCS with 18:1 n-9 or 18:2 n-6 changed the fatty acid spectrum of AR42J cells in a manner that resembles the pattern found, respectively, in VOO and SO rats, although AR42J-L cells were unable to accumulate 20:4 n-6. The AR42J cell line can be a useful tool to assess the effect of membrane compositional changes on acinar cell function. However, differences in baseline characteristics, and perhaps fatty acid metabolism, indicate that results obtained in AR42J cells should be confirmed with experiments in the whole animal.

  9. C-130J Human Vibration

    DTIC Science & Technology

    2005-08-01

    Hulshof , 1999; Dupuis & Zerlett, 1986; Kittusamy & Buchholz, 2004; Seidel, 1993). There is also evidence of intervertebral disc problems and...Bovenzi, M., & Hulshof , C.T.J. (1999). An updated review of epidemiologic studies on the relationship between exposure to whole-body vibration and

  10. 14 CFR Appendices I-J to Part 121 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false [Reserved] I Appendices I-J to Part 121 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR CARRIERS..., FLAG, AND SUPPLEMENTAL OPERATIONS Appendices I-J to Part 121 [Reserved] ...

  11. Inclusive χbJ(nP) decays to D0X

    NASA Astrophysics Data System (ADS)

    Briere, R. A.; Ferguson, T.; Tatishvili, G.; Vogel, H.; Watkins, M. E.; Rosner, J. L.; Alexander, J. P.; Cassel, D. G.; Duboscq, J. E.; Ehrlich, R.; Fields, L.; Galik, R. S.; Gibbons, L.; Gray, R.; Gray, S. W.; Hartill, D. L.; Heltsley, B. K.; Hertz, D.; Kandaswamy, J.; Kreinick, D. L.; Kuznetsov, V. E.; Mahlke-Krüger, H.; Mohapatra, D.; Onyisi, P. U. E.; Patterson, J. R.; Peterson, D.; Riley, D.; Ryd, A.; Sadoff, A. J.; Shi, X.; Stroiney, S.; Sun, W. M.; Wilksen, T.; Athar, S. B.; Patel, R.; Yelton, J.; Rubin, P.; Eisenstein, B. I.; Karliner, I.; Mehrabyan, S.; Lowrey, N.; Selen, M.; White, E. J.; Wiss, J.; Mitchell, R. E.; Shepherd, M. R.; Besson, D.; Pedlar, T. K.; Cronin-Hennessy, D.; Gao, K. Y.; Hietala, J.; Kubota, Y.; Klein, T.; Lang, B. W.; Poling, R.; Scott, A. W.; Zweber, P.; Dobbs, S.; Metreveli, Z.; Seth, K. K.; Tomaradze, A.; Libby, J.; Powell, A.; Wilkinson, G.; Ecklund, K. M.; Love, W.; Savinov, V.; Lopez, A.; Mendez, H.; Ramirez, J.; Ge, J. Y.; Miller, D. H.; Shipsey, I. P. J.; Xin, B.; Adams, G. S.; Anderson, M.; Cummings, J. P.; Danko, I.; Hu, D.; Moziak, B.; Napolitano, J.; He, Q.; Insler, J.; Muramatsu, H.; Park, C. S.; Thorndike, E. H.; Yang, F.; Artuso, M.; Blusk, S.; Khalil, S.; Li, J.; Mountain, R.; Nisar, S.; Randrianarivony, K.; Sultana, N.; Skwarnicki, T.; Stone, S.; Wang, J. C.; Zhang, L. M.; Bonvicini, G.; Cinabro, D.; Dubrovin, M.; Lincoln, A.; Naik, P.; Rademacker, J.; Asner, D. M.; Edwards, K. W.; Reed, J.

    2008-11-01

    Using Υ(2S) and Υ(3S) data collected with the CLEO III detector we have searched for decays of χbJ to final states with open charm. We fully reconstruct D0 mesons with pD0>2.5GeV/c in three decay modes (K-π+, K-π+π0, and K-π-π+π+) in coincidence with radiative transition photons that tag the production of one of the χbJ(nP) states. Significant signals are obtained for the two J=1 states. Recent nonrelativistic QCD (NRQCD) calculations of χbJ(nP)→c cmacr X depend on one nonperturbative parameter per χbJ triplet. The extrapolation from the observed D0X rate over a limited momentum range to a full c cmacr X rate also depends on these same parameters. Using our data to fit for these parameters, we extract results which agree well with NRQCD predictions, confirming the expectation that charm production is largest for the J=1 states. In particular, for J=1, our results are consistent with c cmacr g accounting for about one-quarter of all hadronic decays.

  12. Low sociability is associated with reduced size of the corpus callosum in the BALB/cJ inbred mouse strain.

    PubMed

    Fairless, Andrew H; Dow, Holly C; Toledo, Monica M; Malkus, Kristen A; Edelmann, Michele; Li, Hongzhe; Talbot, Konrad; Arnold, Steven E; Abel, Ted; Brodkin, Edward S

    2008-09-16

    The behavioral manifestations of autism, including reduced sociability (reduced tendency to seek social interaction), may be related to underdevelopment of the corpus callosum (CC). The BALB/cJ inbred mouse strain is a useful model system for testing the relationship between reduced sociability and CC underdevelopment. BALB/cJ mice show low levels of sociability, on average, but substantial intrastrain variability in sociability, as well as striking variability in CC development. This study tested the hypothesis that sociability is positively correlated with CC size within the BALB/cJ inbred strain. 30-day-old BALB/cJ and C57BL/6J mice were tested for sociability towards gonadectomized A/J stimulus mice in a social choice task. The size of the corpus callosum was measured histologically at the midsagittal plane. BALB/cJ mice showed a significant positive correlation between the tendency to sniff the stimulus mouse and size of the CC relative to brain weight. C57BL/6J mice showed consistently high levels of sociability and normal corpus callosum development. These results suggest that abnormal white matter structure is associated with deficits in sociability in BALB/cJ mice. Additional studies are warranted to elucidate the relationship between brain connectivity and sociability in this model system.

  13. Sweet and bitter taste of ethanol in C57BL/6J and DBA2/J mouse strains.

    PubMed

    Blizard, David A

    2007-01-01

    Studies of inbred strains of rats and mice have suggested a positive association between strain variations in sweet taste and ethanol intake. However, strain associations by themselves are insufficient to support a functional link between taste and ethanol intake. We used conditioned taste aversion (CTA) to explore the sweet and bitter taste of ethanol and ability to detect sucrose, quinine and ethanol in C57BL/6J (B6) and DBA/2J (D2) mouse strains that are frequently used in alcohol research. The present study showed that C57BL/6J mice generalized taste aversions from sucrose and quinine solutions to 10% ethanol and, reciprocally, aversions to 10% ethanol generalized to each of these solutions presented separately. Only conditioned aversions to quinine generalized to ethanol in the DBA/2J strain but an aversion conditioned to ethanol did not generalize reciprocally to quinine. Thus, considering these two gustatory qualities, 10% ethanol tastes both sweet and bitter to B6 mice but only bitter to D2. Both strains were able to generalize taste aversions across different concentrations of the same compound. B6 were able to detect lower concentrations of quinine than D2 but both strains were able to detect sucrose and (in contrast to previous findings) ethanol at similar concentrations. The strain-dependent gustatory profiles for ethanol may make an important contribution to the understanding of the undoubtedly complex mechanisms influencing high ethanol preference of B6 and pronounced ethanol avoidance of D2 mice.

  14. DBA2J db/db mice are susceptible to early albuminuria and glomerulosclerosis that correlate with systemic insulin resistance.

    PubMed

    Østergaard, Mette V; Pinto, Vanda; Stevenson, Kirsty; Worm, Jesper; Fink, Lisbeth N; Coward, Richard J M

    2017-02-01

    Diabetic nephropathy (DN) is the leading cause of kidney failure in the world. To understand important mechanisms underlying this condition, and to develop new therapies, good animal models are required. In mouse models of type 1 diabetes, the DBA/2J strain has been shown to be more susceptible to develop kidney disease than other common strains. We hypothesized this would also be the case in type 2 diabetes. We studied db/db and wild-type (wt) DBA/2J mice and compared these with the db/db BLKS/J mouse, which is currently the most widely used type 2 DN model. Mice were analyzed from age 6 to 12 wk for systemic insulin resistance, albuminuria, and glomerular histopathological and ultrastructural changes. Body weight and nonfasted blood glucose were increased by 8 wk in both genders, while systemic insulin resistance commenced by 6 wk in female and 8 wk in male db/db DBA/2J mice. The urinary albumin-to-creatinine ratio (ACR) was closely linked to systemic insulin resistance in both sexes and was increased ~50-fold by 12 wk of age in the db/db DBA/2J cohort. Glomerulosclerosis, foot process effacement, and glomerular basement membrane thickening were observed at 12 wk of age in db/db DBA/2J mice. Compared with db/db BLKS/J mice, db/db DBA/2J mice had significantly increased levels of urinary ACR, but similar glomerular histopathological and ultrastructural changes. The db/db DBA/2J mouse is a robust model of early-stage albuminuric DN, and its levels of albuminuria correlate closely with systemic insulin resistance. This mouse model will be helpful in defining early mechanisms of DN and ultimately the development of novel therapies. Copyright © 2017 the American Physiological Society.

  15. VizieR Online Data Catalog: W1J00 and W2J00 Transit Circle Catalogs (Rafferty+, 2016)

    NASA Astrophysics Data System (ADS)

    Rafferty, T. J.; Holdenried, E. R.; Urban, S. E.

    2016-06-01

    The W1J00, named because it was the first (of two) Washington transit circle catalog to be referred to the Equinox of J2000.0, is the result of observations made with the Six-inch Transit Circle in Washington, D.C., between September 1977 and July 1982. The observing program was structured to be absolute, in the sense that the positions were not explicitly relying on any previous observations. The absolute positions were defined with respect to an internally consistent frame that was unique to the particular instrument. Following the reductions, comparisons with stars from the Hipparcos Catalogue (European Space Agency 1997) revealed unaccounted for systematic differences on the level of 100-200mas. It was decided, therefore, to include data on both the absolute positions reduced in way common to many past Washington transit circle catalogs, as well as the positions differentially adjusted to the system of the Hipparcos Catalog. The W1J00 contains mean positions of 7267 stars and 4383 observations of solar system objects. The majority of the stars fall into two categories; those from the Fifth Fundamental Catalog (FK5; Fricke et al 1988), and those from the Catalog Of 3539 Zodiacal Stars For The Equinox 1950.0 (Robertson 1940). The solar system objects include the Sun, Mercury, Venus, Mars, Jupiter, Saturn, Uranus, Neptune, eight minor planets (Eunomia, Flora, Hebe, Iris, Juno, Metis, Pallas, and Vesta), and the dwarf planet Ceres. Characteristics of the W1J00 catalog: Category Range Average ------------------------------------------------------------- Magnitudes -1.6 to 10.4 7.18 RA standard errors of the mean 15 to 460 mas 98 mas Dec standard errors of the mean 10 to 400 mas 107 mas RA Number of observations / star 3 to 187 10 Dec Number of observations / star 2 to 179 10 Declination coverage -39 to +90 degrees ------------------------------------------------------------- Details of the W1J00 can be found in Rafferty, Holdenried, and Urban (2016, Publ. USNO, 2nd

  16. The jABC Approach to Rigorous Collaborative Development of SCM Applications

    NASA Astrophysics Data System (ADS)

    Hörmann, Martina; Margaria, Tiziana; Mender, Thomas; Nagel, Ralf; Steffen, Bernhard; Trinh, Hong

    Our approach to the model-driven collaborative design of IKEA's P3 Delivery Management Process uses the jABC [9] for model driven mediation and choreography to complement a RUP-based (Rational Unified Process) development process. jABC is a framework for service development based on Lightweight Process Coordination. Users (product developers and system/software designers) easily develop services and applications by composing reusable building-blocks into (flow-) graph structures that can be animated, analyzed, simulated, verified, executed, and compiled. This way of handling the collaborative design of complex embedded systems has proven to be effective and adequate for the cooperation of non-programmers and non-technical people, which is the focus of this contribution, and it is now being rolled out in the operative practice.

  17. Recognition without identification, erroneous familiarity, and déjà vu.

    PubMed

    O'Connor, Akira R; Moulin, Chris J A

    2010-06-01

    jà vu is characterized by the recognition of a situation concurrent with the awareness that this recognition is inappropriate. Although forms of déjà vu resolve in favor of the inappropriate recognition and therefore have behavioral consequences, typical déjà vu experiences resolve in favor of the awareness that the sensation of recognition is inappropriate. The resultant lack of behavioral modification associated with typical déjà vu means that clinicians and experimenters rely heavily on self-report when observing the experience. In this review, we focus on recent déjà vu research. We consider issues facing neuropsychological, neuroscientific, and cognitive experimental frameworks attempting to explore and experimentally generate the experience. In doing this, we suggest the need for more experimentation and a more cautious interpretation of research findings, particularly as many techniques being used to explore déjà vu are in the early stages of development.

  18. Automated Axon Counting in Rodent Optic Nerve Sections with AxonJ.

    PubMed

    Zarei, Kasra; Scheetz, Todd E; Christopher, Mark; Miller, Kathy; Hedberg-Buenz, Adam; Tandon, Anamika; Anderson, Michael G; Fingert, John H; Abràmoff, Michael David

    2016-05-26

    We have developed a publicly available tool, AxonJ, which quantifies the axons in optic nerve sections of rodents stained with paraphenylenediamine (PPD). In this study, we compare AxonJ's performance to human experts on 100x and 40x images of optic nerve sections obtained from multiple strains of mice, including mice with defects relevant to glaucoma. AxonJ produced reliable axon counts with high sensitivity of 0.959 and high precision of 0.907, high repeatability of 0.95 when compared to a gold-standard of manual assessments and high correlation of 0.882 to the glaucoma damage staging of a previously published dataset. AxonJ allows analyses that are quantitative, consistent, fully-automated, parameter-free, and rapid on whole optic nerve sections at 40x. As a freely available ImageJ plugin that requires no highly specialized equipment to utilize, AxonJ represents a powerful new community resource augmenting studies of the optic nerve using mice.

  19. Prescription-event monitoring in Japan (J-PEM).

    PubMed

    Kubota, Kiyoshi

    2002-01-01

    In prescription-event monitoring in Japan (J-PEM), patients are identified by prescriptions in individual pharmacies where drugs are dispensed. The methodology is somewhat different to that used by the Drug Safety Research Unit in the UK, in that two questionnaires, one to the pharmacist and the other to the doctor are sent for each patient and the method of concurrent control is employed in J-PEM. In the data analysis, the list of events reported as a suspected reaction or a reason for stopping the drug is made to generate a signal. In addition, a signal may be generated for some events with the statistically significant difference of crude rates followed by the regression analysis or a follow-up study. In J-PEM, Medical Dictionary for Regulatory Activities (MedDRA) terminology is used for data entry and data analysis. Lowest level terms (LLTs) in MedDRA are used in data entry while a signal is generated using preferred terms (PTs). However, to generate a signal effectively, some PTs may be grouped as one term. In addition, if two terms are so similar, it may be instructed that one of those two terms is normally selected in data entry to avoid confusion. Many more PEM studies could be undertaken to determine if MedDRA can be used for effective signal generation, but the usefulness of MedDRA in J-PEM is still to be determined.

  20. jTracker and Monte Carlo Comparison

    NASA Astrophysics Data System (ADS)

    Selensky, Lauren; SeaQuest/E906 Collaboration

    2015-10-01

    SeaQuest is designed to observe the characteristics and behavior of `sea-quarks' in a proton by reconstructing them from the subatomic particles produced in a collision. The 120 GeV beam from the main injector collides with a fixed target and then passes through a series of detectors which records information about the particles produced in the collision. However, this data becomes meaningful only after it has been processed, stored, analyzed, and interpreted. Several programs are involved in this process. jTracker (sqerp) reads wire or hodoscope hits and reconstructs the tracks of potential dimuon pairs from a run, and Geant4 Monte Carlo simulates dimuon production and background noise from the beam. During track reconstruction, an event must meet the criteria set by the tracker to be considered a viable dimuon pair; this ensures that relevant data is retained. As a check, a comparison between a new version of jTracker and Monte Carlo was made in order to see how accurately jTracker could reconstruct the events created by Monte Carlo. In this presentation, the results of the inquest and their potential effects on the programming will be shown. This work is supported by U.S. DOE MENP Grant DE-FG02-03ER41243.