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Sample records for joseph lounana tnis

  1. Joseph Ames

    NASA Technical Reports Server (NTRS)

    1920-01-01

    Dr. Joseph Sweetman Ames at his desk at the NACA headquarters. Dr. Ames was a founding member of NACA (National Advisory Committee for Aeronautics), appointed by President Woodrow Wilson in 1915. Ames took on NACA's most challenging assignments but mostly represented physics. He chaired the Foreign Service Committee of the newly-founded National Research Council, oversaw the NACA's patent cross-licensing plan that allowed manufacturers to share technologies. Ames expected the NACA to encourage engineering education. He pressed universities to train more aerodynamicists, then structured NACA to give young engineers on-the-job training. Ames gave the NACA a focused vision that was research-based and decided that aerodynamics was the most important field of endeavor. He championed the work of theorists like Max Munk. The world class wind tunnels at Langley Aeronautical laboratory reflected his vision as well as the faith Congress put in him. Ames became chairman of the NACA main committee in 1927. Two years later he accepted the Collier Trophy on behalf on the NACA. He kept the NACA alive when Herbert Hoover tried to eliminate it and transfer its duties to industry. Ames accepted a nomination by Air Minister Hermann Goring to the Deutsche Akademie der Luftfartforschung. Ames then considered it an honor, many Americans did, and was surprised to learn about the massive Nazi investment in aeronautical infrastructure, then six times larger than the NACA. Ames urged the funding for a second laboratory and expansion of the NACA facilities to prepare for war. A stroke in May 1936 paralyzed the right side of his body. He immediately resigned as chairman of the NACA executive committee and in October 1937 he resigned from the NACA main committee. On June 8, 1944 the NACA officially dedicated its new laboratory in Sunnyvale California to Joseph S. Ames. Ames died in 1943, having never stepped foot in the new laboratory that bears his name; the Ames Aeronautical Laboratory

  2. Jean Baptiste Joseph Fourier

    NASA Astrophysics Data System (ADS)

    Sterken, C.

    2003-03-01

    This paper gives a short account of some key elements in the life of Jean Baptiste Joseph Fourier (1768-1830), specifically his relation to Napoleon Bonaparte. The mathematical approach to Fourier series and the original scepticism by French mathematicians are briefly illustrated.

  3. Joseph Conrad: International Narrator

    ERIC Educational Resources Information Center

    Walker, George

    2004-01-01

    This article discusses the contribution made by Joseph Conrad's fictional writing to our understanding of cultural awareness. Never comfortable with his adopted English culture, Conrad used his experiences in different parts of the world during his career in the merchant navy to explore in his writing aspects of cultural dissonance and cultural…

  4. Joseph Lister's first operation

    PubMed Central

    Richardson, Ruth; Rhodes, Bryan

    2013-01-01

    Joseph Lister was still a medical student in 1851 when he served as house surgeon at University College Hospital, London, under John Erichsen. Here we report the first major operation that Lister accomplished, hitherto apparently missed by biographers. We chart his exemplary dealings with an emergency case of eviscerating stab wound in a woman brought to casualty at night, when he had been in post for less than a month. The case demonstrates Lister's fundamental competence at an early stage in his training. We outline the context of debate and controversy over the repair of lacerated gut at the time, and argue that Lister's period at University College London was profoundly formative.

  5. Joseph Priestley's Legacy in America.

    ERIC Educational Resources Information Center

    McMeekin, Dorothy

    2001-01-01

    Discusses the life and work of Joseph Priestley, a scientist of the late eighteenth century who was famous for his work in both Europe and America. Includes a description of the Joseph Priestley house, a museum containing some of his scientific equipment and exhibitions relating to his work. (MM)

  6. PERSPECTIVE VIEW OF THE FIRST BANK OF JOSEPH, LOCATED BETWEEN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PERSPECTIVE VIEW OF THE FIRST BANK OF JOSEPH, LOCATED BETWEEN JOSEPH AND SECOND AVENUE ON MAIN STREET. VIEW LOOKING SOUTHEAST. - Joseph Main Street, Between Joseph & Second Avenues, Joseph, Wallowa County, OR

  7. Joseph Henry and Astronomy

    NASA Astrophysics Data System (ADS)

    Rothenberg, Marc

    2016-01-01

    Joseph Henry (1797-1878) is best known for his work in electromagnetism and as the first secretary of the Smithsonian Institution. But he was also a pioneer solar physicist, an early advocate of US participation in astrophysics, and a facilitator of international cooperation in astronomy. This paper will briefly trace his role in the development of the US astronomical community from the time he taught astronomy at Princeton in the 1830s through his death, focusing on failed efforts to persuade US astronomers and patrons of astronomy that the best path for US astronomy should be astrophysics. He thought that the US could make a more significant contribution to astronomy science by striking out on a less travelled path rather than competing with the established European observatories.

  8. [Joseph Babinski: a complex personality].

    PubMed

    Poirier, Jacques

    2007-10-01

    Joseph Babinski (1857-1932), a Paris hospital neurologist known for the discovery of his eponymous sign, was a highly complex personality. He was known as a handsome but silent "blue-eyed giant". His parents left Poland for Paris after the insurrection of 1848. Joseph and his elder brother Henri (1855-1931) were born in Paris and were therefore French, but they remained devoted to Poland. Joseph suffered from excruciating self-doubt and was meticulous. He was a reasoner and a righter of wrongs. Henri, who trained as a civil engineer at the French National School of Mines, prospected mineral, gold and diamond deposits in various countries. On his return to France at the end of the century, he wrote, under the pseudonym Ali-Bab, a monumental cookbook called "Gastronomie pratique", which was widely acclaimed Joseph and Henri, both unmarried, lived together and formed an inseparable couple. Joseph Babinski had no religious, political or ideological commitments. Some areas of his private life still remain rather shadowy. PMID:18447056

  9. PERSPECTIVE VIEW OF THE FIRST BANK OF JOSEPH, LOCATED AT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PERSPECTIVE VIEW OF THE FIRST BANK OF JOSEPH, LOCATED AT THE NORTHEAST CORNER OF SECOND AND MAIN, VIEW LOOKING NORTHEAST. - Joseph Main Street, Between Joseph & Second Avenues, Joseph, Wallowa County, OR

  10. ASK Talks With Joseph Rothenberg

    NASA Technical Reports Server (NTRS)

    Rothenberg, Joseph

    2002-01-01

    Recently retired NASA administrator Joseph Rothenberg reflects on project management during the Apollo era at the start of his career, as well as the history of, and changes in, project management over his years at NASA. He concludes by describing what he sees as NASA's most important needs in the near future.

  11. Joseph Hooker: a philosophical botanist.

    PubMed

    Endersby, Jim

    2008-06-01

    The nineteenth-century British botanist, Joseph Dalton Hooker,was one of the people whose career became a model for that of the modern,professional scientist.However,he preferred to refer to himself as a philosophical botanist, rather than a professional. This paper explores the reasons for this choice,and analyses Hooker's imperial approach to plant classification, the consequences of which are still with us. PMID:18535350

  12. The Birth of Joseph Gabriel

    PubMed Central

    Cantine, Anne Touhill

    2013-01-01

    In this column, a mother shares the story of the birth of her first child. With confidence in the process of birth and in her ability to give birth, and with the support, confidence, and encouragement of her mother and sisters, Anne manages to cope with strong contractions through a busy day. Finally, her husband realizes how fast labor is progressing. Baby Joseph was born less than 2 hours after arrival at the hospital. PMID:24868130

  13. Joseph Priestley and the Psychology of Style.

    ERIC Educational Resources Information Center

    Moran, Michael G.

    Joseph Priestley, in his "A Course of Lectures on Oratory and Criticism," developed a psychological theory of style. The "Course" covers three main topics: traditional rhetorical arts of invention, arrangement, and style. Borrowing from the ideas of David Hartley, the association psychologist; Joseph Addison, the aesthetician; and Adam Smith, the…

  14. 75 FR 15430 - Chief Joseph Hatchery Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-29

    ... Bonneville Power Administration Chief Joseph Hatchery Program AGENCY: Bonneville Power Administration (BPA... announces the availability of the ROD to implement the proposed action identified in BPA's Chief Joseph Hatchery Program Environmental Impact Statement (DOE/EIS-0384, November 2009). BPA has decided to fund...

  15. Joseph Maxwell on mediumistic personifications.

    PubMed

    Alvarado, Carlos S

    2016-09-01

    The study of mediumship received much impetus from the work of psychical researchers. This included ideas about the phenomena of personation, or changes in attitudes, dispositions and behaviours shown by some mediums that supposedly indicated discarnate action. The aim of this Classic Text is to reprint passages about this topic from the writings of French psychical researcher Joseph Maxwell (1858-1938), which were part of the contributions of some psychical researchers to reconceptualize the manifestations in psychological terms. Maxwell suggested these changes in mediums were a production of their subconscious mind. His ideas are a reflection of previous theorization about secondary personalities and a particular example of the contributions of psychical researchers to understand the psychology of mediumship. PMID:27473729

  16. Joseph Henry and the Telegraph

    NASA Astrophysics Data System (ADS)

    Hochfelder, David

    1997-04-01

    Morse's telegraph rested upon three scientific advances which occured between 1800 and 1830: the development of battery technology, the formulation of laws governing the behavior of electrical components in circuits, and the discovery of electromagnetic phenomena. Joseph Henry was crucial to the development of the early telegraph. His work on electromagnetism made it possible for the electric current to manifest itself as useful mechanical work. Henry developed electromagnets of sufficient lifting power, but which drew relatively small currents; these magnets were the heart of Morse's telegraph receiver. Morse also used electromagnets as relays, which allowed him to transmit signals over great distances. Morse often acknowledged his debt to Henry, and the two enjoyed a cordial working relationship until the mid-1840s. But during the bitter and protracted litigation over Morse's patent, Henry testified (unwillingly, he claimed) against the inventor. This began a lifelong quarrel between the two men, the specifics of which were tedious and petty. In general terms, however, their conflict arose over different notions regarding scientific discovery and technological innovation.

  17. Joseph Beuys: trauma and catharsis.

    PubMed

    Ottomann, C; Stollwerck, P L; Maier, H; Gatty, I; Muehlberger, T

    2010-12-01

    Joseph Beuys was one of the most significant artists of the 20th century. He was a gunner and radio operator in the German Air Force during World War II, and was severely injured several times. In March 1943 he had a life-changing experience after the dive bomber he was assigned to crashed in the Crimean peninsula. This trauma influenced Beuys' entire artistic career, and is known in art history as the 'Tartar Legend' or 'Tartar Myth'. Profoundly affected by the crash, the severe trauma, the near-death experience and his rescue, which he perceived as a "rebirth", Beuys no longer saw himself, other people or society as a whole in the same way as previously. With his new consciousness, he ignored boundaries and created visions whereby all mankind could experience the healing he had undergone. Beuys did not bring society far enough for the turning point towards "the healing of the world" to be visible, yet today it is important to keep his work alive as a record of his extraordinary strength, which arose from trauma and severe injury, and was carried by a passionate commitment to mankind and to life itself. PMID:21393290

  18. Rethinking Joseph Janangelo's "Joseph Cornell and the Artistry of Composing Persuasive Hypertexts"

    ERIC Educational Resources Information Center

    College Composition and Communication, 2007

    2007-01-01

    This article presents several excerpts from an article written by Joseph Janangelo titled "Joseph Cornell and the Artistry of Composing Persuasive Hypertexts." In his article, Janangelo suggested that Cornell's work and ideas about composing model intelligent ways to composing persuasive nonsequential text. Janangelo also wondered if the use of…

  19. Joseph Conrad's tormented Rescue (fantasy).

    PubMed

    Freedman, William

    2014-02-01

    Joseph Conrad was a notoriously tormented writer for whom the creative act was often a punishment severe enough to drive him into paralyzing depressions that delayed the completion of his novels, sometimes for years. By far the most agonizing of these projects was The Rescue, a novel he began in 1898, abandoned a year later, tried unsuccessfully to continue several times over the next two decades, but was only able to resume in 1918 and to complete, after another tortured two-year struggle, in 1920. An explanation for this incapacity, that is powerfully suggested by the novel's evocative title and perhaps unintentionally ironic subtitle (A Romance of the Shallows) has not yet been explored. Using Freud's 1910 essay on the rescue fantasy, "Contributions to the Psychology of Love: A Special Type of Choice of Object Made by Men," and Emanuel Berman's instructive revision and expansion of the concept in his 2003 American Imago essay, "Ferenczi, Rescue, and Utopia," I argue that a substantial explanation for Conrad's tormented history with The Rescue is ascribable to its quite remarkably faithful treatment of a rescue fantasy with deep and disabling resonance for its author. More specifically, the difficulty was compounded by the novel's dramatization of the soul-crushing conflict between two such fantasies: one in the service of the masculine ideal of unflinching dedication to a heroic purpose, the other promising satisfaction to the equally potent demands of emotional and sexual desire. Features of Conrad's narrative fit so tightly and consistently with the theory as Freud (and Abraham) proposed and as Berman elaborated it that The Rescue offers itself as one of those rare and reinforcing instances wherein the literary text seems to validate the psychoanalytic theory at least as persuasively as the theory "understands" the text. PMID:24555549

  20. 6. View northeast of Ten Acre Lot with Joseph Fry ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. View northeast of Ten Acre Lot with Joseph Fry Farm complex (center) and Beehive House (right)in the background - Joseph Fry Farm Landscape, 2153 South County Trail Road (U.S. Route 2), East Greenwich, Kent County, RI

  1. 5. Photocopy of photograph (original negative owned by St. Joseph's ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Photocopy of photograph (original negative owned by St. Joseph's Church) Photographer unknown, pre 1905 INTERIOR BEFORE 1905 ALTERATIONS - St. Joseph's Roman Catholic Church, Main Street, Westphalia, Osage County, MO

  2. [Diseases and death of Joseph Pilsudski].

    PubMed

    Jeśman, Czesław; Młudzik, Agnieszka; Kula, Agnieszka

    2012-06-01

    Marshal Joseph Pilsudski did not belong to individuals who cared for their health. He avoided physicians and treatment. He appreciated only legion physicians such as Gen. Dr Stanisław Ruppert, Col. Dr Marcin Wroczyński and Col. DrAndrzej Mozołowki. Joseph Pilsudski was a heavy smoker and suffered from pulmonary emphysema for many years. In 1933 he caught a severe flu accompanied by some hepatic ailments and began losing his weight. In 1935, his liver became enlarged. He started vomiting and was very weak. All consultations were ineffective. He died from primary carcinoma of bile ducts on 12 May, 1935. PMID:22891570

  3. Joseph Rotblat: Influences, Scientific Achievements and Legacy

    ERIC Educational Resources Information Center

    Underwood, Martin

    2008-01-01

    Joseph Rotblat was one of the most distinguished nuclear physicists and peace campaigners of the post Second World War period. His peace activities rank alongside those of Albert Einstein and Bertrand Russell; he won the Nobel Peace Prize, jointly with the Pugwash movement, that he helped found. However, he made significant contributions to…

  4. Content, Joseph Schwab and German "Didaktik"

    ERIC Educational Resources Information Center

    Deng, Zongyi

    2015-01-01

    This article attempts to extend and deepen the conversation concerning the knowledge-based approach to curriculum espoused by Michael Young in his 2013 "JCS" paper through revisiting the structure of the disciplines thinking of Joseph Schwab and German "Didaktik." It argues that curriculum making requires a theory of knowledge…

  5. Selected Papers of Joseph T. Impellitteri.

    ERIC Educational Resources Information Center

    Baran, Anna DeSantis; Gilli, Angelo C., Sr.

    1975-01-01

    The collection of selected papers of Joseph T. Impellitteri reprints in full, or excerpts from, 46 unpublished position and conference papers, research and program proposals, and project reports, and from 20 published articles, chapters from edited collections, bulletins and special studies which Impellitteri authored or co-authored. The papers…

  6. Joseph Priestley: Docter Phlogiston or Reverend Oxygen?

    PubMed

    Fara, Patricia

    2010-09-01

    In propaganda material, people are often presented in black-and-white terms as either a villain or a hero. Although Joseph Priestley is denigrated for believing in the discredited substance phlogiston, he is also celebrated for discovering oxygen. PMID:20708802

  7. Interview--Cliff Joseph: Art Therapist, Pioneer, Artist.

    ERIC Educational Resources Information Center

    Riley-Hiscox, Anna

    1997-01-01

    Interview of Cliff Joseph, one of the first African Americans to participate in the American Art Therapy Association and to become a registered art therapist and teacher. Details Joseph's impact on art therapy and cultural and social issues, as well as his relationships with other prominent art therapists. (MKA)

  8. Tribes of Men: John Joseph Mathews and Indian Internationalism

    ERIC Educational Resources Information Center

    Lutenski, Emily

    2012-01-01

    In this article, the author discusses John Joseph Mathews and Indian internationalism. As an old man, Osage intellectual, writer, and historian, John Joseph Mathews recalled his expatriation from the United States during the 1920s. After growing up in Pawhuska, Oklahoma, seat of the Osage Nation, where he had been born in 1894 to a white mother…

  9. 33 CFR 110.193a - St. Joseph Bay, Fla.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false St. Joseph Bay, Fla. 110.193a... ANCHORAGE REGULATIONS Anchorage Grounds § 110.193a St. Joseph Bay, Fla. (a) The anchorage grounds—(1... northeast of the north entrance channel to Port St. Joe, Florida. (2) Explosives Anchorage Area 2....

  10. 33 CFR 110.193a - St. Joseph Bay, Fla.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false St. Joseph Bay, Fla. 110.193a... ANCHORAGE REGULATIONS Anchorage Grounds § 110.193a St. Joseph Bay, Fla. (a) The anchorage grounds—(1... northeast of the north entrance channel to Port St. Joe, Florida. (2) Explosives Anchorage Area 2....

  11. 33 CFR 110.193a - St. Joseph Bay, Fla.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false St. Joseph Bay, Fla. 110.193a... ANCHORAGE REGULATIONS Anchorage Grounds § 110.193a St. Joseph Bay, Fla. (a) The anchorage grounds—(1... northeast of the north entrance channel to Port St. Joe, Florida. (2) Explosives Anchorage Area 2....

  12. Joseph F. Poland (1908-1991)

    NASA Astrophysics Data System (ADS)

    Johnson, A. Ivan

    On June 4, 1991, AGU Fellow Joseph Fairfield Poland died in a Sacramento, Calif., hospital at the age of 83 after a long fight with Parkinson's Disease. A recognized expert on land subsidence and a retiree from the U.S. Geological Survey's Water Resources Division, his death occurred only 2 weeks after the end of the 4th International Symposium on Land Subsidence, held in Houston, Tex. Frequently known as “Mr. Land Subsidence,” it was appropriate that the proceedings of that symposium had been dedicated to him.Born in Boston, Poland earned a bachelor's degree in geology from Harvard University in 1929. He was resident geologist for Tropical Oil Company in Colombia from 1929 to 1931. After returning to the United States, Poland earned his master's degree in geology from Stanford University in 1935, taught groundwater hydrology, and consulted on groundwater and geophysical problems in the West and Southwest.

  13. Joseph Leidy: his contributions to otology.

    PubMed

    Meyers, A

    1976-09-01

    Few men of science have contributed more to our understanding of the workings of nature than Joseph Leidy. Philosopher, anatomist, paleontologist, botanist, educator, and natural scientist in the purest sense of the work, Leidy's interest in the humanities and in all aspects of nature lent itself to his exact descriptions of new species and unchartered anatomic realms. His insistence on man's acquaintance with nature fostered a humanistic and sensitive approach to life, something that needs more emphasis today. This communication deals with Leidy's life, his philosophy, and his unique dedication to the study of nature. An appreciation and understanding of his anatomic expertise, particularly of the temporal bone, hopefully will sensitize the modern otologist to the heart and mind of one that preceded him. PMID:786235

  14. 1. Historic American Buildings Survey Joseph Hill, Photographer October 1936 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Joseph Hill, Photographer October 1936 #12 EARLY RED BRICK HOUSE, Elk and Prospect Sts., Galena, Illinois - Galena Doorways, Red Brick House, Elk & Prospect Streets, Galena, Jo Daviess County, IL

  15. 6. Detail of pilaster cap. Aug. 10, 1936. Joseph Hill, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Detail of pilaster cap. Aug. 10, 1936. Joseph Hill, photographer, copied from small photo taken by survey member. - Jansonist Colony, Steeple Building, Main & Bishop Hill Streets, Bishop Hill, Henry County, IL

  16. 3. West and south elevations. Joseph Hill, photographer, copied from ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. West and south elevations. Joseph Hill, photographer, copied from photo lent by Evelyn S. Craig. August 1936. - Jansonist Colony, Steeple Building, Main & Bishop Hill Streets, Bishop Hill, Henry County, IL

  17. 1. Historic American Buildings Survey Joseph Hill, Photographer August 1936 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Joseph Hill, Photographer August 1936 FIRST ORIGINAL STORE AND POSTOFFICE, COPY OF AN EARLY PHOTOGRAPH. LENT BY EVELYN S. CRAIG - Jansonist Colony, Colony Store & Post Office, Main & Bishop Hill Streets, Bishop Hill, Henry County, IL

  18. 7. Detail of balcony rail. August 1936. Joseph Hill, photographer, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Detail of balcony rail. August 1936. Joseph Hill, photographer, copied from small photo taken by survey member. - Jansonist Colony, Steeple Building, Main & Bishop Hill Streets, Bishop Hill, Henry County, IL

  19. 6. Historic American Buildings Survey Joseph Hill, Photographer April 1, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Historic American Buildings Survey Joseph Hill, Photographer April 1, 1936 MANTEL 1352 W. Washington Blvd., Chicago - Chicago Ironwork, William M. Strong Estate (Cast Iron House & Gate), 1352 West Washington Boulevard, Chicago, Cook County, IL

  20. 4. Historic American Buildings Survey Joseph Hill, Photographer April 5, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Historic American Buildings Survey Joseph Hill, Photographer April 5, 1936 INRON WINDOW GRILL, 1352 W. WASHINGTON ST. CHICAGO - Chicago Ironwork, William M. Strong Estate (Cast Iron House & Gate), 1352 West Washington Boulevard, Chicago, Cook County, IL

  1. 2. Historic American Buildings Survey Joseph Hill, Photographer May 10, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Historic American Buildings Survey Joseph Hill, Photographer May 10, 1936 CAST IRON GATE AT 1352 W. Washington Blvd., Chicago - Chicago Ironwork, William M. Strong Estate (Cast Iron House & Gate), 1352 West Washington Boulevard, Chicago, Cook County, IL

  2. 2. PERSPECTIVE LOOKING NORTH BY 300 DEGREES CHIEF JOSEPH DAM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. PERSPECTIVE LOOKING NORTH BY 300 DEGREES CHIEF JOSEPH DAM INTERPRETIVE CENTER IN FOREGROUND - Columbia River Bridge at Bridgeport, State Route 17 spanning Columbia River, Bridgeport, Douglas County, WA

  3. 7. CHIEF JOSEPH DAM AND POWERHOUSE TO LEFT OF PICTURE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. CHIEF JOSEPH DAM AND POWERHOUSE TO LEFT OF PICTURE COLUMBIA RIVER BRIDGE AT BRIDGEPORT TO RIGHT OF DOWNSTREAM - Columbia River Bridge at Bridgeport, State Route 17 spanning Columbia River, Bridgeport, Douglas County, WA

  4. 3. Historic American Buildings Survey Joseph Hill, Photographer August 1936 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Historic American Buildings Survey Joseph Hill, Photographer August 1936 BRONZE TABLET HISTORICAL MARKER - Hobson Grist Mill (Monument & Millstones), DuPage County Pioneer Park, Naperville, Du Page County, IL

  5. 12. Historic American Buildings Survey Joseph Hill, Photographer July 10, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Historic American Buildings Survey Joseph Hill, Photographer July 10, 1936 SOUTH ELEVATION (Copied from student's drawing, Dept. of Architecture, Armour Institute of Technology. Chicago) - Keating House, U.S. Highway 430, Fayville, Alexander County, IL

  6. 1. Historic American Buildings Survey Joseph Hill, Photographer Oct. 25, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Joseph Hill, Photographer Oct. 25, 1936 #1 MAXIENER HOUSE 104 South Bench Street Galena, Illinois - Galena Doorways, Elizabeth Maxiener Cottage, 104 South Bench Street, Galena, Jo Daviess County, IL

  7. 1. Historic American Buildings Survey Joseph Hill, Photographer 1936 #4 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Joseph Hill, Photographer 1936 #4 FORMERLY SISTERS OF MERCY CONVENT 226 North Bench Street, Galena, Illinois. - Galena Doorways, Sisters of Mercy Convent, 226 North Bench Street, Galena, Jo Daviess County, IL

  8. 1. Historic American Buildings Survey Joseph Hill, Photographer October 1936 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Joseph Hill, Photographer October 1936 #2 PORTER HOUSE, 110 Bench St. Galena, Illinois - Galena Doorways, Porter House, 110 North Bench Street, Galena, Jo Daviess County, IL

  9. 1. Historic American Buildings Survey Copied by Joseph Hill from ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Copied by Joseph Hill from an old photograph loaned by Alice Snyder, Galena, Illinois. SOUTH EAST ELEVATION - Grace Episcopal Church, South Prospect Street, Galena, Jo Daviess County, IL

  10. 1. Historic American Buildings Survey Joseph Hill, Photographer October 1936 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Joseph Hill, Photographer October 1936 #5 GRIMM HOUSE 608 South Bench Street, Galena. - Galena Doorways, Heike Grimm House, 608 South Bench Street, Galena, Jo Daviess County, IL

  11. 1. Historic American Buildings Survey Joseph Hill, Photographer October 1936 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Joseph Hill, Photographer October 1936 #7 KLINGEL HOUSE ON BENCH STREET Galena, Illinois - Galena Doorways, Peter Klingel House, Bench Street, Galena, Jo Daviess County, IL

  12. 1. Historic American Buildings Survey Joseph Hill, Photographer October 1936 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Joseph Hill, Photographer October 1936 #3 HEMPSTEAD HOUSE (about 1846) 611 South Bench Street, Galena, Ill. - Galena Doorways, Charles Hempstead House, 611 South Bench Street, Galena, Jo Daviess County, IL

  13. 1. Historic American Buildings Survey Joseph Hill, Photographer October 1936 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Joseph Hill, Photographer October 1936 #13 EARLY WAREHOUSE South Main Street, South of Booth, Galena, Illinois - Galena Doorways, Warehouse, South Main Street, Galena, Jo Daviess County, IL

  14. 1. Historic American Buildings Survey Joseph Hill, Photographer October 1936 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Joseph Hill, Photographer October 1936 #6 CALDERWOOD HOUSE (1839) North Bench Street, Galena, Ill. - Celia Calderwood House, North Bench Street, Galena, Jo Daviess County, IL

  15. 1. Historic American Buildings Survey Joseph Hill, Photographer October 1936 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Joseph Hill, Photographer October 1936 #8 STAIR RAILING TELFORD SHOP Bench Street, Galena, Ill. - Galena Doorways, Telford Shop, Bench Street, Galena, Jo Daviess County, IL

  16. 1. Historic American Buildings Survey Joseph Hill, Photographer October 25, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Joseph Hill, Photographer October 25, 1936 #9 HARMONY LODGE ON BENCH STREET (1858) - Galena Doorways, Harmony Lodge of Odd Fellows, Bench Street, Galena, Jo Daviess County, IL

  17. 1. Historic American Buildings Survey Joseph Hill, Photographer October 1936 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Joseph Hill, Photographer October 1936 #10 Early Methodist Church, Later Odd Fellows Lodge on Bench Street. - Galena Doorways, First Methodist Church, Bench Street, Galena, Jo Daviess County, IL

  18. 1. Historic American Buildings Survey Joseph Hill, Photographer October 1936 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Joseph Hill, Photographer October 1936 #16 OLD DOWLING HOUSE (Broadway), Galena - Galena Doorways, John Dowling House, Main & Diagonal Streets, Galena, Jo Daviess County, IL

  19. 18. Historic American Buildings Survey Joseph Hill, Photographer May 26, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. Historic American Buildings Survey Joseph Hill, Photographer May 26, 1936 FIREPLACE IN DINING ROOM, The Davenport House, Rock Island Arsenal - Rock Island Arsenal, Building No. 346, Davenport Drive, Arsenal Grounds, Rock Island, Rock Island County, IL

  20. 1. Historic American Buildings Survey Joseph Hill, Photographer July 1936 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Joseph Hill, Photographer July 1936 STAIR RAILING, 66 WEST OAK STREET - Chicago Ironwork, 66 West Oak Street (Cast Iron Stair Railing), 66 West Oak Street, Chicago, Cook County, IL

  1. 2. Historic American Buildings Survey Joseph Hill, Photographer July 1936 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Historic American Buildings Survey Joseph Hill, Photographer July 1936 BALCONY RAILING, 945 NO. DEARBORN ST. JUDGE CARPENTER'S HOME - Chicago Ironwork, Judge Carpenter House (Cast Iron Balcony Railing), 945 North Dearborn Street, Chicago, Cook County, IL

  2. 3. Historic American Buildings Survey Joseph Hill, Photographer June, 1936 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Historic American Buildings Survey Joseph Hill, Photographer June, 1936 DETAIL OF BALCONY RAILING, 945 NO. DEARBORN ST. JUDGE CARPENTER'S HOME - Chicago Ironwork, Judge Carpenter House (Cast Iron Balcony Railing), 945 North Dearborn Street, Chicago, Cook County, IL

  3. Cholangicarcinoma Presenting as a Sister Mary Joseph Nodule

    PubMed Central

    Rangegowda, Devaraja; Vyas, Tanmay; Grover, Shrruti; Joshi, YK; Sharma, Chhagan; Sahney, Amrish

    2016-01-01

    Sister Mary Joseph nodules represent metastatic cancer of the umbilicus. More than half of these cases are attributable to gastrointestinal malignancies including gastric, colonic, and pancreatic cancer. In addition, gynecologic (ovarian, uterine cancer), unknown primary tumors, and, rarely, bladder or respiratory malignancies may cause umbilical metastasis. We report the case of a Sister Mary Joseph nodule originating from a hilar cholangiocarcinoma. Umbilical nodules should prompt clinical evaluation, as these tumors are usually associated with poor prognosis. PMID:27144207

  4. Joseph Henry's Conception of Scientific Knowledge

    NASA Astrophysics Data System (ADS)

    Theerman, Paul

    1997-04-01

    Joseph Henry, America's premier physicist and physics teacher in the mid-nineteenth century, had decided views of scientific knowledge. These were expressed in two ways. First of all, scientific knowledge led to moral betterment. Thus the study of science was a morally good thing. This was not only because it led to the contemplation of God's creation, which was a standard reason justifying the study of science dating from the Scientific Revolution and even earlier. More importantly, the study of science itself was a moral discipline, imparting to scientists the habits and virtues of truthfulness, respect for others, care and diligence, and the discernment of meaningful patterns from experience. The moral ideals of science were expressed most strongly in Henry's upholding the international "Republic of Science"; conversely, cheapening science was a sign of moral failure. Second, for Henry and his generation, science provided a path to sure truth, separate from falsehood of both the politics and the quackery that characterized mid-century public life. Henry promoted this in his championing of the Smithsonian Institution a scientific establishment, against the ideas of others who wanted to make it a literary establishment or a training school for teachers. For Henry, the Smithsonian's scientific reputation would be established by relying on careful peer review in its publications, and supporting established scientists to write authoritative popular works. The purpose of both these activities was to raise the profile of science in the United States and further establish science and the scientific method as a guide to public life.

  5. Straight talk with...Joseph Schwartz.

    PubMed

    Ratner, Mark

    2012-06-01

    On 17 May, Human Genome Sciences (HGS) formally rejected a $2.6 billion unsolicited takeover offer by GlaxoSmithKline. The Maryland-based biotech firm had long partnered with the UK drug giant to develop drugs including Benlysta (belimumab), HGS's first drug on the market and the first new medicine approved to fight lupus in 50 years. But, at $13 a share, GSK's bid was deemed "inadequate" by the HGS board. Recent history in the biotech sector shows how high the stakes are in such negotiations. Since last November, six biopharma buyouts have exceeded $1 billion each, with Gilead Sciences' purchase last year of the hepatitis C specialist Pharmasset topping the charts at a whopping $11.2 billion, the highest ever paid for a clinical-stage biotech and an 89% premium to its share price at the time. More recently, in April AstraZeneca paid $1.3 billion for Ardea Biosciences, a company with cancer and gout drugs in the pipeline but nothing on the market.One person watching the upward clime of such deals is biopharma analyst Joseph Schwartz, a managing director at Leerink Swann in Boston. Mark Ratner sought out Schwartz, who was named the top stock picker for pharmaceuticals in the last year's FT/StarMine Analyst Awards, for his views on what's behind the recent buyout spending. PMID:22673987

  6. Joseph Rotblat: influences, scientific achievements and legacy

    NASA Astrophysics Data System (ADS)

    Underwood, Martin

    2008-11-01

    Joseph Rotblat was one of the most distinguished nuclear physicists and peace campaigners of the post Second World War period. His peace activities rank alongside those of Albert Einstein and Bertrand Russell; he won the Nobel Peace Prize, jointly with the Pugwash movement, that he helped found. However, he made significant contributions to science, and in particular to the medical applications of accelerators, radiation and radio-nuclides. In this article his early work and influences in Poland are described. He then joined James Chadwick at Liverpool University and began work on the cyclotron recently constructed there. Rotblat then, together with Chadwick, joined the Manhattan Project. This experience was to shape his life. He stayed at Los Alamos for less than a year before walking out. He was suspected of being a spy. Rotblat then became Professor of Physics at St Bartholomew's Medical College and pioneered the use of a 15 MeV linear accelerator in treatment and research. He made fundamental contributions to understanding the effects of the fallout from nuclear bomb tests. He also, together with Patricia Lindop, made important contributions to understanding the biological effects of radiation.

  7. [Bioethical arguments in Joseph Ratzinger's thinking].

    PubMed

    Martínez-Carbonell López, Alfonso

    2014-01-01

    In the dense theological thought of Joseph Ratzinger before his election as pope, we find fundamental contributions to contemporary bioethics. Starting from the assumption of the close relationship between faith and science he incorporates a necessary theological dimension in the bioethical dialogue that illuminates and clarifies the answers to the real questions raised in bioethical actions. On the one hand, there is the question of the origin of man that is understood as God's creation as opposed to a purely biological origin to which a modern pseudoscientific stance wants to confine it. On the other hand, there is the question about man's identity, which is understood as the image of God, from which stems the inviolable dignity and sacredness of human life, overcoming scientistic materialism. Finally, we find the question of how to treat the ″other″, even the embryo, as a result of its lofty dignity, analyzing the ethical and legal consequences that exude from their nature and are summarized in the duty to protect and respect the other which the law should protect against the abuse of those who are stronger. PMID:25329412

  8. Joseph Priestley, oxygen, and the enlightenment.

    PubMed

    West, John B

    2014-01-01

    Joseph Priestley (1733–1804) was the first person to report the discovery of oxygen and describe some of its extraordinary properties. As such he merits a special place in the history of respiratory physiology. In addition his descriptions in elegant 18th-century English were particularly arresting, and rereading them never fails to give a special pleasure. The gas was actually first prepared by Scheele (1742–1786) but his report was delayed. Lavoisier (1743–1794) repeated Priestley's initial experiment and went on to describe the true nature of oxygen that had eluded Priestley, who never abandoned the erroneous phlogiston theory. In addition to oxygen, Priestley isolated and characterized seven other gases. However, most of his writings were in theology because he was a conscientious clergyman all his life. Priestley was a product of the Enlightenment and argued that all beliefs should be able to stand the scientific scrutiny of experimental investigations. As a result his extreme liberal views were severely criticized by the established Church of England. In addition he was a supporter of both the French and American Revolutions. Ultimately his political and religious attitudes provoked a riot during which his home and his scientific equipment were destroyed. He therefore emigrated to America in 1794 where his friends included Thomas Jefferson and Benjamin Franklin. He settled in Northumberland, Pennsylvania although his scientific work never recovered from his forced departure. But the descriptions of his experiments with oxygen will always remain a high point in the history of respiratory physiology. PMID:24285268

  9. Saint Joseph's University Institute for Environmental Stewardship

    SciTech Connect

    McCann, Michael P; Springer, Clint

    2013-10-15

    Task A: Examination of the physiological, morphological, and reproductive responses of Panicum virgatum (switchgrass) cultivars identified as potential biofuel producing cultivars as well as naturally-occurring varieties of switchgrass to projected changes in climate for the central portion of the United States. This project was a multi-year project set in a field site located at the Konza Prairie Biological Station near Manhattan, KS USA. At the field site we planted switchgrass collected from regions in Kansas, Oklahoma, and Texas. After a year of establishment we implemented a set of two-year water treatments that examined the responses in physiology, growth and development of switchgrass to predicted changes in precipitation amount for the central United States. After this experiment was completed we performed a second set of experiments that examined the responses of switchgrass physiology, growth, and development to changes in precipitation frequency. We also included in this analysis how genome size of individuals influenced their responses to precipitation frequency changes. Generally, we found switchgrass to be unresponsive to realistic predictions of precipitation changes for the Central Plains of the United States. These studies have provided significant insight into how this important grassland species will respond to future climate change from both an ecological and applied biological perspective. Finally, we provided insight into the mechanism through which this species changes in the face of altered water availability by not supporting the hypothesis that the control of switchgrass responses to changes in precipitation is altered by genome size. Task B: Installation of an extensive green roof system on the Science Center at Saint Joseph's University for research, research-training and educational outreach activities. An experimental green roof system was designed and installed by an outside contractor (Roofmeadows) on the roof of the Science Center

  10. Obituary: Richard Joseph Elston, 1960-2004

    NASA Astrophysics Data System (ADS)

    Jannuzi, Buell Tomasson; Bechtold, Jill

    2004-12-01

    Richard Joseph Elston, known for his development of innovative astronomical instrumentation, died on 26 January 2004 in Gainesville, Florida, after a four-year battle with Hodgkin's lymphoma. A professor of astronomy at the University of Florida, Richard had an unusually broad range of interests and skills, and a willingness to share his passion for astronomy with others, which made him a highly valued member of the astronomical community. Born 1 July 1960, in Albuquerque, New Mexico, Richard was the son of a geologist father and journalist mother. His childhood interest in astronomy and instrumentation matured as he majored in physics and astronomy at the University of New Mexico (BS, 1983) under the mentorship of Michael Zeilik. Richard pursued his PhD in astronomy at the University of Arizona and earned his degree in 1988. He pioneered the use of IR arrays for deep imaging surveys of the sky to study galaxy formation, and completed his thesis Search for Rapidly Forming Galaxies at High Redshift under the direction of George Rieke. Richard's graduate work included the first detection of galaxies at intermediate redshifts with evolved populations too red to have been identifiable from optical imaging surveys alone. In the Astrophysical Journal Letters in 1988, he, George Rieke, and Marcia Rieke reported the discovery of this new class of galaxies, now known as EROs (Extremely Red Objects), important as the possible progenitors of present day elliptical galaxies. Following post-doctoral positions at Kitt Peak National Observatory from 1988 to 1991 and at the Observatories of the Carnegie Institution of Washington from 1991 to 1992, Richard joined the scientific staff of Cerro Tololo Inter-American Observatory in Chile, part of the NSF's National Optical Astronomy Observatory. By 1994, he had become head of CTIO's IR instrumentation program and was leading the development of new instruments for the US astronomical community. In 1996, Richard married astronomer

  11. Saint Joseph's University Institute for Environmental Stewardship

    SciTech Connect

    McCann, Michael; Springer, Clint

    2014-06-18

    future climate scenarios is local adaptation and not necessarily genome size as has been hypothesized in the literature. Task B: Installation of an extensive green roof system on the Science Center at Saint Joseph's University for research, research-training and educational outreach activities. An experimental green roof system was designed and installed by an outside contractor (Roofmeadows) on the roof of the Science Center at Saint Joseph's University. The roof system includes four test plots, each with a different drainage system, instrumentation to monitor storm water retention, roof deck temperature, heat flux into and out of the building, rain fall, wind speed and direction, relative humidity and heat emission from the roof system. The vegetative roof was planted with 26 species of plants, distributed throughout the roof area, to assess species/variety growth and coverage characteristics, both in terms of the different drain layer systems, and in terms of the different exposures along the north to south axis of the building. Analysis of the drain layer performance, in terms of storm water retention, shows that the aggregate (stone) drainage layer system performed the best, with the moisture management mat system second, and the geotextile drain layer and reservoir sheet layer systems coming in last. This information is of value in the planning and design of vegetative roof systems since the different types of drainage layer systems have different installation costs and different weights. The different drainage layer systems also seem to be having an impact on plant growth and spread with the test plot with the reservoir sheet layer actually having the poorest plant coverage and plant spread of all areas of the roof studied. Plant growth performance analysis is ongoing, but significant differences have been observed in the third growing season ('13) along the north to south axis, with most species doing better towards the northern end of the roof (in terms of

  12. Saint Joseph's University Institute for Environmental Stewardship

    SciTech Connect

    McCann, Michael P.; Springer, Clint J.

    2014-06-05

    future climate scenarios is local adaptation and not necessarily genome size as has been hypothesized in the literature. Task B: Installation of an extensive green roof system on the Science Center at Saint Joseph's University for research, research-training and educational outreach activities. An experimental green roof system was designed and installed by an outside contractor (Roofmeadows) on the roof of the Science Center at Saint Joseph's University. The roof system includes four test plots, each with a different drainage system, instrumentation to monitor storm water retention, roof deck temperature, heat flux into and out of the building, rain fall, wind speed and direction, relative humidity and heat emission from the roof system. The vegetative roof was planted with 26 species of plants, distributed throughout the roof area, to assess species/variety growth and coverage characteristics, both in terms of the different drain layer systems, and in terms of the different exposures along the north to south axis of the building. Analysis of the drain layer performance, in terms of storm water retention, shows that the aggregate (stone) drainage layer system performed the best, with the moisture management mat system second, and the geotextile drain layer and reservoir sheet layer systems coming in last. This information is of value in the planning and design of vegetative roof systems since the different types of drainage layer systems have different installation costs and different weights. The different drainage layer systems also seem to be having an impact on plant growth and spread with the test plot with the reservoir sheet layer actually having the poorest plant coverage and plant spread of all areas of the roof studied. Plant growth performance analysis is ongoing, but significant differences have been observed in the third growing season ('13) along the north to south axis, with most species doing better towards the northern end of the roof (in terms of

  13. Saint Joseph's University Institute for Environmental Stewardship

    SciTech Connect

    McCann, Micahel P.; Springer, Clint J.

    2014-06-03

    future climate scenarios is local adaptation and not necessarily genome size as has been hypothesized in the literature. Task B: Installation of an extensive green roof system on the Science Center at Saint Joseph's University for research, research-training and educational outreach activities. An experimental green roof system was designed and installed by an outside contractor (Roofmeadows) on the roof of the Science Center at Saint Joseph's University. The roof system includes four test plots, each with a different drainage system, instrumentation to monitor storm water retention, roof deck temperature, heat flux into and out of the building, rain fall, wind speed and direction, relative humidity and heat emission from the roof system. The vegetative roof was planted with 26 species of plants, distributed throughout the roof area, to assess species/variety growth and coverage characteristics, both in terms of the different drain layer systems, and in terms of the different exposures along the north to south axis of the building. Analysis of the drain layer performance, in terms of storm water retention, shows that the aggregate (stone) drainage layer system performed the best, with the moisture management mat system second, and the geotextile drain layer and reservoir sheet layer systems coming in last. This information is of value in the planning and design of vegetative roof systems since the different types of drainage layer systems have different installation costs and different weights. The different drainage layer systems also seem to be having an impact on plant growth and spread with the test plot with the reservoir sheet layer actually having the poorest plant coverage and plant spread of all areas of the roof studied. Plant growth performance analysis is ongoing, but significant differences have been observed in the third growing season ('13) along the north to south axis, with most species doing better towards the northern end of the roof (in terms of

  14. Sister Mary Joseph nodule-A case report with review of literature

    PubMed Central

    Dar, Ishrat Hussain; Kamili, Mqtasid Ahmed; Dar, Showkat Hussain; Kuchaai, Faiz Ahmed

    2009-01-01

    Sister Mary Joseph nodule or Sister Mary Joseph Sign refers to a palpable nodule bulging into the umbilicus as a result of metastasis of a malignant cancer in the pelvis or abdomen. A rare case of Sister Mary Joseph nodule, manifesting as ascites, cachexia and bleeding per rectum, is presented without any primary tumor despite extensive search for the same. PMID:21772912

  15. 1. Historic American Buildings Survey Joseph Hill's Photograph Copy of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Joseph Hill's Photograph Copy of Original Photograph May5, 1936 SOUTH ELEVATION 1352 W.WASHINGTON BLVD. -1362 CHICAGO, ILLINOIS. - Chicago Ironwork, William M. Strong Estate (Cast Iron House & Gate), 1352 West Washington Boulevard, Chicago, Cook County, IL

  16. Video from Panel Discussion with Joseph Fraumeni and David Schottenfeld

    Cancer.gov

    Video footage from Panel Discussion with Joseph Fraumeni and David Schottenfeld on Cancer Epidemiology over the Last Half-Century and Thoughts on the Future. The discussion took place on May 11, 2012, when DCEG hosted Dr. Schottenfeld as a Visiting Scholar.

  17. Perils of Accommodation: The Case of Joseph W. Holley

    ERIC Educational Resources Information Center

    O'Brien, Thomas V.

    2007-01-01

    This study examines accommodationism, a tactic of racial uplift used by black school founders and teachers in the Jim Crow South. For founders, accommodationism was a dangerous process of collaboration, resistance, and compromise. The subject under study is Joseph Winthrop Holley. Born in South Carolina, Holley studied in the North at Phillips…

  18. Visions and Re-Visions of Charles Joseph Minard.

    ERIC Educational Resources Information Center

    Friendly, Michael

    2002-01-01

    Describes the contributions of Charles Joseph Minard to statistical graphics, noting the time course of his work and providing background on his famous effort, the flow-map depiction of Napoleon's march on Moscow. Explores some modern re-visions of this famous graphic from an information visualization perspective. (SLD)

  19. The Reaches of Conscience: An Interview with Joseph P. Lash.

    ERIC Educational Resources Information Center

    McCaffrey, Patrick

    1984-01-01

    Few people knew Eleanor Roosevelt as well as author Joseph P. Lash, author of the Pulitzer prize-winning "Eleanor and Franklin." In this interview Lash talks about Mrs. Roosevelt's personal characteristics, her educational theories, the role she played in attracting minorities to the Democratic Party, and FDR's influence on her. (RM)

  20. A Vignette of an American Sporting Sculptor: Joseph D. Brown.

    ERIC Educational Resources Information Center

    Field, David A.

    In this lecture, about sixty of the more important small and large sports sculptures and medals of Professor Joseph D. Brown are discussed and illustrated through the use of 35mm color slides. A brief description of the sculptor's life, interests, and philosophy of sport is also given. (MB)

  1. 2. Historic American Buildings Survey Joseph Hill, Photographer October 28, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Historic American Buildings Survey Joseph Hill, Photographer October 28, 1936 #1 DOORWAY MAXIENER HOUSE 104 South Bench Street, Galena, Ill. (Said to be oldest frame house in Galena) - Galena Doorways, Elizabeth Maxiener Cottage, 104 South Bench Street, Galena, Jo Daviess County, IL

  2. 1. Historic American Buildings Survey Joseph Hill, Photographer March 10, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Joseph Hill, Photographer March 10, 1936 CAST IRON BALCONY RAIL AND WROUGHT IRON WINDOW RAILING 945 NORTH DEARBORN STREET, CHICAGO - Chicago Ironwork, Judge Carpenter House (Cast Iron Balcony Railing), 945 North Dearborn Street, Chicago, Cook County, IL

  3. Joseph v. Brady: Synthesis Reunites What Analysis Has Divided

    ERIC Educational Resources Information Center

    Thompson, Travis

    2012-01-01

    Joseph V. Brady (1922-2011) created behavior-analytic neuroscience and the analytic framework for understanding how the external and internal neurobiological environments and mechanisms interact. Brady's approach offered synthesis as well as analysis. He embraced Findley's approach to constructing multioperant behavioral repertoires that found…

  4. Science and Worldviews in the Classroom: Joseph Priestley and Photosynthesis

    ERIC Educational Resources Information Center

    Matthews, Michael R.

    2009-01-01

    This paper elaborates on the life and publications of Joseph Priestley, the eighteenth-century polymath. The paper outlines his particular place in the European Enlightenment; it stresses the importance of philosophy and worldview in his scientific work on pneumatic chemistry, the composition of air, and his discovery of the process of…

  5. Pioneer in Behavioral Pharmacology: A Tribute to Joseph V. Brady

    ERIC Educational Resources Information Center

    Barrett, James E.

    2008-01-01

    The contributions of Joseph V. Brady to behavioral pharmacology span more than 50 years and range from early studies using the Estes-Skinner ("conditioned emotional response") procedure to examine drug effects and various physiological processes in experimental animals to the implementation of mobile methadone treatment services and to small group…

  6. Obituary: Richard Joseph Elston, 1960-2004

    NASA Astrophysics Data System (ADS)

    Jannuzi, Buell Tomasson; Bechtold, Jill

    2004-12-01

    Richard Joseph Elston, known for his development of innovative astronomical instrumentation, died on 26 January 2004 in Gainesville, Florida, after a four-year battle with Hodgkin's lymphoma. A professor of astronomy at the University of Florida, Richard had an unusually broad range of interests and skills, and a willingness to share his passion for astronomy with others, which made him a highly valued member of the astronomical community. Born 1 July 1960, in Albuquerque, New Mexico, Richard was the son of a geologist father and journalist mother. His childhood interest in astronomy and instrumentation matured as he majored in physics and astronomy at the University of New Mexico (BS, 1983) under the mentorship of Michael Zeilik. Richard pursued his PhD in astronomy at the University of Arizona and earned his degree in 1988. He pioneered the use of IR arrays for deep imaging surveys of the sky to study galaxy formation, and completed his thesis Search for Rapidly Forming Galaxies at High Redshift under the direction of George Rieke. Richard's graduate work included the first detection of galaxies at intermediate redshifts with evolved populations too red to have been identifiable from optical imaging surveys alone. In the Astrophysical Journal Letters in 1988, he, George Rieke, and Marcia Rieke reported the discovery of this new class of galaxies, now known as EROs (Extremely Red Objects), important as the possible progenitors of present day elliptical galaxies. Following post-doctoral positions at Kitt Peak National Observatory from 1988 to 1991 and at the Observatories of the Carnegie Institution of Washington from 1991 to 1992, Richard joined the scientific staff of Cerro Tololo Inter-American Observatory in Chile, part of the NSF's National Optical Astronomy Observatory. By 1994, he had become head of CTIO's IR instrumentation program and was leading the development of new instruments for the US astronomical community. In 1996, Richard married astronomer

  7. Obituary: Joseph Wyan Chamberlain, 1928-2004

    NASA Astrophysics Data System (ADS)

    Hunten, Donald M.

    2004-12-01

    Joseph W. Chamberlain died at home with his family on April 14 2004 after a long illness. He was born August 24, 1928 and raised in Boonville, Missouri, where his father was the doctor. There was no doubt that both Joe and his elder brother Gilbert would also become doctors, but Joe's first class in comparative anatomy at the University of Missouri convinced him that this was not his destiny and he immediately switched to physics and astronomy. He obtained a Masters degree in physics and moved on to the University of Michigan; his advisor was Lawrence Aller and he was also strongly influenced by Leo Goldberg. Early in 1952 he was awarded a PhD and began work at the Air Force Cambridge Research Center where he changed his interests to the upper atmosphere. Among his duties was liaison with research groups at several universities, and I met him when he visited us at the University of Saskatchewan one very cold winter day. He was soon posted to work with Aden Meinel at Yerkes Observatory, where he was added to the faculty and became the leader of the group when Meinel departed to organize the Kitt Peak National Observatory. He himself moved there in 1962 as Associate Director for Space Science; the name of the division was later changed to Planetary Science. He recruited a strong group to work on planetary atmospheres and several group members played important roles in the Mariner 10, Pioneer Venus, Viking, Voyager and Galileo missions. He was elected to the National Academy of Sciences in 1965. As leader of the group he recruited at Kitt Peak, Joe earned the admiration and loyalty of us all. He strongly preferred doing science to his administrative tasks, but he was still effective at the latter. He was considerably bothered that his superiors, especially the managing boards with which he had to deal, did not always meet his high standards. Joe's friends and colleagues felt, and still feel, that he would have been much happier as a member of a teaching faculty, and

  8. Obituary: Joseph Wyan Chamberlain, 1928-2004

    NASA Astrophysics Data System (ADS)

    Hunten, Donald M.

    2004-12-01

    Joseph W. Chamberlain died at home with his family on April 14 2004 after a long illness. He was born August 24, 1928 and raised in Boonville, Missouri, where his father was the doctor. There was no doubt that both Joe and his elder brother Gilbert would also become doctors, but Joe's first class in comparative anatomy at the University of Missouri convinced him that this was not his destiny and he immediately switched to physics and astronomy. He obtained a Masters degree in physics and moved on to the University of Michigan; his advisor was Lawrence Aller and he was also strongly influenced by Leo Goldberg. Early in 1952 he was awarded a PhD and began work at the Air Force Cambridge Research Center where he changed his interests to the upper atmosphere. Among his duties was liaison with research groups at several universities, and I met him when he visited us at the University of Saskatchewan one very cold winter day. He was soon posted to work with Aden Meinel at Yerkes Observatory, where he was added to the faculty and became the leader of the group when Meinel departed to organize the Kitt Peak National Observatory. He himself moved there in 1962 as Associate Director for Space Science; the name of the division was later changed to Planetary Science. He recruited a strong group to work on planetary atmospheres and several group members played important roles in the Mariner 10, Pioneer Venus, Viking, Voyager and Galileo missions. He was elected to the National Academy of Sciences in 1965. As leader of the group he recruited at Kitt Peak, Joe earned the admiration and loyalty of us all. He strongly preferred doing science to his administrative tasks, but he was still effective at the latter. He was considerably bothered that his superiors, especially the managing boards with which he had to deal, did not always meet his high standards. Joe's friends and colleagues felt, and still feel, that he would have been much happier as a member of a teaching faculty, and

  9. Astronaut Paul Weitz gets physical examination from Astronaut Joseph Kerwin

    NASA Technical Reports Server (NTRS)

    1973-01-01

    Astronaut Paul J. Weitz, Skylab 2 pilot, gets a physical examination by a fellow crewman during the 28-day Skylab 2 mission. Scientist-Astronaut Joseph P. Kerwin, Skylab 2 science pilot and a doctor of medicine, uses a stethoscope to check the Weitz's heartbeat. They are in the Orbital Workshop crew quarters of the Skylab 1 and 2 space station in Earth orbit. This photograph was taken by Charles Conrad Jr., Skylab 2 commander.

  10. Astronaut Joseph Kerwin strapped into sleep restraint in crew quarters

    NASA Technical Reports Server (NTRS)

    1973-01-01

    Scientist-Astronaut Joseph P. Kerwin, Skylab 2 science pilot, is photographed strapped into the sleep restraint in the crew quarters of the Orbital Workshop of the Skylab 1 and 2 space station cluster in Earth orbit. Kerwin is wearing the special cap which contains biomedical instrumentation for the M133 Sleep Monitoring Experiment. The purpose of the M133 experiment is to evaluate quantity and quality of sleep during prolonged space flight by the analysis of electroencephalographic (EEG) and electrooculographic (EOG) activity.

  11. In praise of Joseph Priestley - the particle physicist!

    NASA Astrophysics Data System (ADS)

    Jones, G. T.

    1991-05-01

    Joseph Priestley (1733 - 1804), known more as a chemist, made important contributions to the evolution of our view of the structure of matter. To commemorate the notorious Birmingham riots of July 1791, during which his house was burnt and his work destroyed, and following which he left England for the United States after three years in London, this article highlights his major contribution to what we now call particle physics

  12. Remembering Joseph Mayo and His Contributions to Animal Science | Poster

    Cancer.gov

    By Carolynne Keenan, Guest Writer In the 1990s, when Joseph Mayo, D.V.M, ran out of gas leading coworkers home from a meeting in Bethesda, he pulled over to the side of the road on I-270 and waited for help. He didn’t have to wait long; within a few minutes a passing motorist took pity on the group of scientists and offered them a lift back to Fort Detrick.

  13. Astronaut Joseph Kerwin takes blood sample from Astronaut Charles Conrad

    NASA Technical Reports Server (NTRS)

    1973-01-01

    Scientist-Astronaut Joseph P. Kerwin (right), Skylab 2 science pilot and a doctor of medicine, takes a blood sample from Astronaut Charles Conrad Jr., Sylab 2 commander, as seen in this reproduction taken from a color television transmission made by a TV camera aboard the Skylab 1 and 2 space station cluster in Earth orbit. The blood sampling was part of the Skylab Hematology and Immunology Experiment M110 series.

  14. Joseph V. Brady: Synthesis Reunites What Analysis Has Divided

    PubMed Central

    Thompson, Travis

    2012-01-01

    Joseph V. Brady (1922–2011) created behavior-analytic neuroscience and the analytic framework for understanding how the external and internal neurobiological environments and mechanisms interact. Brady's approach offered synthesis as well as analysis. He embraced Findley's approach to constructing multioperant behavioral repertoires that found their way into designing environments for astronauts as well as studying drug effects on human social behavior in microenvironments. Brady created translational neurobehavioral science before such a concept existed. One of his most lasting contributions was developing a framework for ethical decision making to protect the rights of the people who participate in scientific research. PMID:23450040

  15. Professor Joseph Warren Horton (1889-1967): biological engineer.

    PubMed

    Zeitlin, Gerald L

    2005-02-01

    Joseph Warren Horton graduated with a degree in electrical engineering from the Massachusetts Institute of Technology (MIT) in 1914. He became involved in the early development of electrical measurement devices, televised image transmission, and the detection of underwater sound transmission. In the mid-1930s he was appointed the first leader of the newly created Department of Biological Engineering at MIT and in this position he made major contributions to the application of physics to human physiology, in particular by increasing the safety of explosive inhalational anaesthetic agents. PMID:15682231

  16. Joseph Harris of Trevecka: Scientist, Artisan, Servant of the Crown

    NASA Astrophysics Data System (ADS)

    Griffiths, M.

    2012-01-01

    A major goal of natural philosophy in the early eighteenth century was the search for accurate positional longitude. This quest demanded the most precise instruments and the most meticulous observations in astronomy and geophysics. Joseph Harris strode across these disciplines making a valuable contribution to the studies of astronomy, navigation, horology and magnetic variation. He later served his country by standardising weights and measures of coinage as Assay Master at the Royal Mint. Yet his prowess is little known or acknowledged. This paper describes and examines his life and roles.

  17. DCEG Symposium to Honor Joseph F. Fraumeni, Jr. | Poster

    Cancer.gov

    By Nancy Parrish, Staff Writer On May 6, the Division of Cancer Epidemiology and Genetics (DCEG) will sponsor a symposium to honor 50 years of leadership from its founding director, Joseph F. Fraumeni, Jr., M.D., who stepped down from the position in July 2012. The conference, entitled “Cancer Epidemiology: From Pedigrees to Populations,” will highlight critical findings in cancer epidemiology from the last 50 years, as well as opportunities for future research directions. Long History of Leadership and Discovery

  18. Joseph Rotblat, the bomb and anomalies from his archive.

    PubMed

    Underwood, Martin C

    2013-06-01

    Professor Sir Joseph Rotblat made significant contributions to nuclear physics and worked on the development of the atomic bomb. He walked out of the Manhattan Project after working there for less than a year, the only scientist to do so. Rotblat gave a comprehensive account of his time at Los Alamos. His Archive is now becoming available and papers contained therein are inconsistent with some aspects of his account. The reasons as to how such anomalies and contradictions could occur are considered. PMID:22190230

  19. 78 FR 6173 - Diana Del Grosso, Ray Smith, Joseph Hatch, Cheryl Hatch, Kathleen Kelley, Andrew Wilklund, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-29

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF TRANSPORTATION Surface Transportation Board Diana Del Grosso, Ray Smith, Joseph Hatch, Cheryl Hatch, Kathleen... Smith, Joseph Hatch, Cheryl Hatch, Kathleen Kelley, Andrew Wilklund, and Richard Kosiba...

  20. Joseph Campbell, Jung, Anne Tyler, and "The Cards": The Spiritual Journey in "Searching for Caleb."

    ERIC Educational Resources Information Center

    Thomson, Karen M.

    Joseph Campbell, Carl Jung, and Anne Tyler have all dealt with spiritual journeys and card reading in their writings. In his book "Tarot Revelations," Joseph Campbell discusses his first association with tarot cards, dating from 1943, when he was introduced to the symoblism of playing cards by his friend and mentor, Heinrich Zimmer. Carl Jung was…

  1. Leader and Spokesman for a People in Exile: Chief Joseph and the Nez Perce

    ERIC Educational Resources Information Center

    Jain, Samvit

    2009-01-01

    This article discusses Chief Joseph's surrender that marked the beginning of his diplomatic stand for justice in Indian Territory, where his tribe was forcibly exiled in accordance with American Indian policy of the time. Joseph battled for the repatriation of the Nez Perce through protests and other legal means, winning the support of the growing…

  2. 77 FR 3797 - Joseph Deluca, D.O.; Dismissal of Proceeding

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-25

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF JUSTICE Drug Enforcement Administration Joseph Deluca, D.O.; Dismissal of Proceeding On July 16, 2010, the Deputy Assistant... Joseph Deluca, D.O. (Registrant), of Coral Springs, Florida. The Show Cause Order proposed the...

  3. 78 FR 66801 - Norfolk Southern Railway Company-Abandonment Exemption-in St. Joseph County, Ind.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-06

    ... Surface Transportation Board Norfolk Southern Railway Company--Abandonment Exemption--in St. Joseph County... 1152 subpart F-Exempt Abandonments to abandon a total of approximately 1.5 miles of rail line located in the City of ] South Bend, St. Joseph County, Ind., extending easterly from milepost PY 1.90...

  4. Science Advisor and Applied Physicist: Joseph Henry Serves His Country

    NASA Astrophysics Data System (ADS)

    Rothenberg, Marc

    1997-04-01

    When Joseph Henry accepted the postion of secretary of the Smithsonian in 1846, his career changed radically. Although he never ceased thinking of himself as a research scientist and educator, thereafter his chief roles were those of science administrator and advisor to both the executive and legislative branches of the federal government for both science and technology. His effectiveness as an advocate became more important than his skill as an experimental physicist. Even when he entered the laboratory, his role had changed. No longer was he concerned with basic research. As a member of various government boards and committees, Henry spent the last three decades of his life concerned with the application of fundamental knowledge for the improvement of the human condition. This paper will discuss Henry's service on behalf of his country.

  5. Joseph Lister: his contributions to early experimental physiology

    PubMed Central

    Howard, Edward R.

    2013-01-01

    Joseph Lister (1827–1912) acquired a lifelong interest in histology and experimental physiology while a student at University College London between 1848 and 1852. His first two publications in 1853 were histological studies of the contractile tissue of the iris and the skin. Studies of inflammation in 1855 progressed to experiments on the nervous control of arteries, using techniques of peripheral nerve division, spinal cord section and needle stimulation of the brain. This interest in nervous mechanisms led to innovative experiments on gut motility and the autonomic nervous system, from which he inferred that sympathetic nerve control was mediated via intrinsic neuronal plexuses in the gut wall, a mode of action confirmed 100 years later, in 1964–65. It is not generally known that Lister was elected FRS for this early experimental work and that his early commitment to experimental science and microscopy was the background to his later work on the development of surgical antisepsis.

  6. Astronaut Joseph Kerwin test subject Lower Body Negative Pressure experiment

    NASA Technical Reports Server (NTRS)

    1973-01-01

    Scientist-Astronaut Joseph P. Kerwin, Skylab 2 science pilot, serves as test subject for the Lower Body Negative Pressure Experiment. Astronaut Paul J. Weitz, Skylab 2 pilot, assists Kerwin with the blood pressure cuff. They are in the experiment and work area of the Orbital Workshop crew quarters of the Skylab 1 and 2 space station cluster in Earth orbit. Kerwin is lying in the lower body negative pressure device. The purpose of the M092 experiment is to provide information concerning the time course of cardiovascular adaptation during flight, and to provide inflight data for predicting the degree of orthostatic intolerance and impairment of physical capacity to be expected upon return to Earth environment. The data collected in support of M092 are blood pressure, heart rate, body temperature, vectorcardiogram, LBNPD pressure, leg volume changes, and body weight.

  7. Joseph Gurney Barclay and the 1860 10-inch Cooke refractor

    NASA Astrophysics Data System (ADS)

    Barclay, C. E.

    2006-12-01

    Joseph Gurney Barclay (1816-1898) was a partner in the banking firm of Barclay, Bevan & Co. He was, like his grandfather, Robert Barclay of Clapham, a keen Astronomer who observed regularly at his home Knotts Green House in Leyton, Essex, England, and he was a frequent contributor to the Monthly Notices of the Royal Astronomical Society. Employing professional astronomers, he made many original observations, especially following the acquisition of a 10-inch Cooke refractor in 1860. Gifted to the Radcliffe Observatory, Oxford in 1885, the 'Barclay Equatorial' continued in professional use until 1935 when it was removed to Marlborough College in Wiltshire, England, where it is now in full computerized use following complete restoration.

  8. Science and Worldviews in the Classroom: Joseph Priestley and Photosynthesis

    NASA Astrophysics Data System (ADS)

    Matthews, Michael R.

    2009-06-01

    This paper elaborates on the life and publications of Joseph Priestley, the eighteenth-century polymath. The paper outlines his particular place in the European Enlightenment; it stresses the importance of philosophy and worldview in his scientific work on pneumatic chemistry, the composition of air, and his discovery of the process of photosynthesis (or the ‘restoration of air’ as it was called at the time); finally the paper indicates ways in which Priestley’s work on photosynthesis can be utilised in the school classroom to advance the understanding of scientific subject matter, to promote an understanding of the nature of scientific procedure and methodology, and finally to evaluate some basic tenets of the European Enlightenment that Priestley so passionately advocated.

  9. Photographic copy of photograph, Joseph Yolo, photographer, 1936 (original print ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of photograph, Joseph Yolo, photographer, 1936 (original print located at U.S. Bureau of Reclamation Upper Columbia Area Office, Yakima, Washington). "WAHT A GOVERNMENT CANAL AND AN ASSURED WATER SUPPLY WILL DO IN A DESERT AREA IS SHOWN IN THIS AIR VIEW OF A SECTION OF THE YAKIMA FEDERAL RECLAMATION PROJECT IN CENTRAL WASHINGTON. THE MAIN CANAL IS SEEN RUNNING DOWN THE MIDDLE OF THE VALLEY WITH PATCHES OF ORCHARDS AND FIELDS ON EITHER SIDE, BUT ABOVE THE CANAL LINE THE SAGE BRUSH DESERT REMAINS, AS CAN BE SEEN ON THE LEFT. THE YAKIMA PROJECT SUPPORTS MORE THAN 110,000 PEOPLE IN A TERRITORY WHICH WAS DESERT 35 YEARS AGO. MANY OF THE ORIGINAL SETTLERS WHO CAME, LIKE THOSE WHO ARE NOW SETTLING ON THE VALE PROJECT, TO BREAK THE RAW DESERT LAND, ARE STILL LIVING ON THESE NEATLY CHECKERBOARDED FARMS" - Kachess Dam, Kachess River, 1.5 miles north of Interstate 90, Easton, Kittitas County, WA

  10. Joseph Rotblat: Moral Dilemmas and the Manhattan Project

    NASA Astrophysics Data System (ADS)

    Veys, Lucy

    2013-12-01

    John Fitzgerald Kennedy famously said, "One man can make a difference and every man should try."1 Joseph Rotblat (1908-2005) was the quintessence of Kennedy's conviction. He was the only scientist who left Los Alamos after it transpired that the atomic bomb being developed there was intended for use against adversaries other than Nazi Germany. I explore Rotblat's early research in Warsaw and Liverpool, which established his reputation as a highly capable experimental physicist, and which led him to join the Manhattan Project at Los Alamos in 1944. I examine his motivation for resigning from the project in 1945, and the unwillingness of his fellow scientists to follow suit, which draws attention to the continuing discourse on the responsibility of scientists for the consequences of their research.

  11. Pierre-Joseph Macquer: Chemistry in the French Enlightenment.

    PubMed

    Lehman, Christine

    2014-01-01

    Despite recent studies of chemistry courses and of academic research at the beginning of the eighteenth century, the perception of chemistry in the French Enlightenment has often been overshadowed by Lavoisier's works. This article proposes three specific case studies selected from Pierre Joseph Macquer's (1718-84) rich career to show the continuous evolution of chemistry throughout the century: medicinal chemistry through the application of the Comte de La Garaye's metallic salt solutions, the emergence of industrial chemistry through a few of Macquer's evaluations at the Bureau du Commerce, and finally communal academic research through the experiments on diamonds using Tschirnhaus's lens. These examples attempt to illustrate the innovative, creative, dynamic, multicultural, and multifaceted chemistry of the Enlightenment. PMID:26103758

  12. Joseph Lister and the performance of antiseptic surgery

    PubMed Central

    Worboys, Michael

    2013-01-01

    This article highlights a neglected feature of Joseph Lister's work, namely how, in addition to promoting germ theories and the principles of the antiseptic system, he also devoted much time and effort to communicating the performative aspects of antisepsis and of the many other surgical innovations that he developed. Attention to ‘detail’ and striving for ‘improvement’ were crucial to Listerian practice, and he sought to convey his credo in three main ways: first, his publications aimed at ‘bringing the subject out in the same sort of way as it had been worked out by himself’; second, he set out strict protocols and information on materials and methods, yet also encouraged surgeons to improvise; and third, he made himself an exemplar of a new form of professionalism, which made constancy and vigilance in practice a moral duty for surgeons. PMID:24686323

  13. Joseph Rotblat and the moral responsibilities of the scientist.

    PubMed

    Underwood, Martin Clifford

    2009-06-01

    Professor Sir Joseph Rotblat was one of the most distinguished scientists and peace campaigners of the post second world war period. He made significant contributions to nuclear physics and worked on the development of the atomic bomb. He then became one of the world's leading researchers into the biological effects of radiation. His life from the early 1950s until his death in August 2005 was devoted to the abolition of nuclear weapons and peace. For this he was awarded the Nobel Peace Prize, together with Pugwash Conferences on Science and World Affairs (that he helped found) in 1995. His work in this area ranked with that of Albert Einstein and Bertrand Russell and this article is an attempt to summarise his life, achievements, but in particular outline his views on the moral responsibilities of the scientist. He is a towering intellectual figure and his contributions to mankind should be better known and more widely understood. PMID:19247813

  14. 1. Historic American Buildings Survey Joseph Hill, Photographer August 10th, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Joseph Hill, Photographer August 10th, 1936 (Copied from small photo taken by survey members) OLD APARTMENT HOUSE - Jansonist Colony, Old Apartment House, Main Street, Bishop Hill, Henry County, IL

  15. School Public Relations and the Principalship: An Interview with Joseph Murphy.

    ERIC Educational Resources Information Center

    Sweetland, Scott R.; Cybulski, Timonty G.

    2002-01-01

    Interview with Joseph Murphy, professor and head of the Ohio Principals Leadership Academy at The Ohio State University. Murphy answers questions about principal leadership, administrator preparation, and school public relations. (PKP)

  16. Joseph's Story: A Case Study of Late-Onset Necrotizing Enterocolitis From Early Birth to Recovery.

    PubMed

    Gephart, Sheila M; Martin, Laura B; Kijewski, Amy; Johnson, Scott R

    2015-01-01

    Although necrotizing enterocolitis (NEC) is often catastrophic among premature infants, most cases occur in the first month after birth. This case study presents Joseph's story about a 24-week surviving twin who developed severe NEC at 5 months of age just days before he was to go home. The purpose of this case study report is to place Joseph and his parents' experience in the context of what is known about NEC risk factors, clinical presentation, and treatment, and then to offer recommendations to healthcare professionals to support families from NEC diagnosis to recovery. Now 5 years old, Joseph continues to manage consequences of NEC including deafness, developmental delay, multiple food allergies, and recurrent gastrointestinal challenges from short gut syndrome. Although NEC struck late and kept Joseph in the neonatal intensive care unit for 228 days, its consequences remain with this resilient child and his family. PMID:26505849

  17. The way of sex: Joseph Needham and Jolan Chang.

    PubMed

    Rocha, Leon Antonio

    2012-09-01

    This paper analyses the understandings of Daoist alchemy and Chinese sexuality of Joseph Needham and his friend and correspondent, the Chinese-Swedish writer Jolan Chang (Chang Chung-lan, 1917-2002). Using the extensive correspondence between the two men, as well as Needham's files on "inner alchemy" deposited at the Needham Research Institute, the paper begins with a partial reconstruction of a 1977 symposium, chaired by Needham, to promote Chang's new book, The Tao of Love and Sex: The Ancient Chinese Way to Ecstasy. Needham and Chang's visions of Chinese sex are then read against excerpts from Science and Civilisation in China, specifically Volume V: Chemistry and Chemical Technology, Part 5: Spagyrical Discovery and Invention: Physiological Alchemy (1983). Three inter-related aspects are explored. First, reading Science and Civilisation in China against materials in the Needham archives offers crucial hints to Needham's historiography and historical practice. Second, the way that Daoist regimens came to be actively reconstructed and repackaged as practices concerned with the enhancement of sexual pleasure and intensity. Third, the investigation of the networks and circulations of assumptions, visions, fantasies about "China". PMID:22652507

  18. Fibroblasts of Machado Joseph Disease patients reveal autophagy impairment.

    PubMed

    Onofre, Isabel; Mendonça, Nuno; Lopes, Sara; Nobre, Rui; de Melo, Joana Barbosa; Carreira, Isabel Marques; Januário, Cristina; Gonçalves, António Freire; de Almeida, Luis Pereira

    2016-01-01

    Machado Joseph Disease (MJD) is the most frequent autosomal dominantly inherited cerebellar ataxia caused by the over-repetition of a CAG trinucleotide in the ATXN3 gene. This expansion translates into a polyglutamine tract within the ataxin-3 protein that confers a toxic gain-of-function to the mutant protein ataxin-3, contributing to protein misfolding and intracellular accumulation of aggregates and neuronal degeneration. Autophagy impairment has been shown to be one of the mechanisms that contribute for the MJD phenotype. Here we investigated whether this phenotype was present in patient-derived fibroblasts, a common somatic cell type used in the derivation of induced pluripotent stem cells and subsequent differentiation into neurons, for in vitro disease modeling. We generated and studied adult dermal fibroblasts from 5 MJD patients and 4 healthy individuals and we found that early passage MJD fibroblasts exhibited autophagy impairment with an underlying mechanism of decreased autophagosome production. The overexpression of beclin-1 on MJD fibroblasts reverted partially autophagy impairment by increasing the autophagic flux but failed to increase the levels of autophagosome production. Overall, our results provide a well-characterized MJD fibroblast resource for neurodegenerative disease research and contribute for the understanding of mutant ataxin-3 biology and its molecular consequences. PMID:27328712

  19. Fibroblasts of Machado Joseph Disease patients reveal autophagy impairment

    PubMed Central

    Onofre, Isabel; Mendonça, Nuno; Lopes, Sara; Nobre, Rui; de Melo, Joana Barbosa; Carreira, Isabel Marques; Januário, Cristina; Gonçalves, António Freire; de Almeida, Luis Pereira

    2016-01-01

    Machado Joseph Disease (MJD) is the most frequent autosomal dominantly inherited cerebellar ataxia caused by the over-repetition of a CAG trinucleotide in the ATXN3 gene. This expansion translates into a polyglutamine tract within the ataxin-3 protein that confers a toxic gain-of-function to the mutant protein ataxin-3, contributing to protein misfolding and intracellular accumulation of aggregates and neuronal degeneration. Autophagy impairment has been shown to be one of the mechanisms that contribute for the MJD phenotype. Here we investigated whether this phenotype was present in patient-derived fibroblasts, a common somatic cell type used in the derivation of induced pluripotent stem cells and subsequent differentiation into neurons, for in vitro disease modeling. We generated and studied adult dermal fibroblasts from 5 MJD patients and 4 healthy individuals and we found that early passage MJD fibroblasts exhibited autophagy impairment with an underlying mechanism of decreased autophagosome production. The overexpression of beclin-1 on MJD fibroblasts reverted partially autophagy impairment by increasing the autophagic flux but failed to increase the levels of autophagosome production. Overall, our results provide a well-characterized MJD fibroblast resource for neurodegenerative disease research and contribute for the understanding of mutant ataxin-3 biology and its molecular consequences. PMID:27328712

  20. Franz Joseph Gall and music: the faculty and the bump.

    PubMed

    Eling, Paul; Finger, Stanley; Whitaker, Harry

    2015-01-01

    The traditional story maintains that Franz Joseph Gall's (1758-1828) scientific program began with his observations of schoolmates with bulging eyes and good verbal memories. But his search to understand human nature, in particular individual differences in capacities, passions, and tendencies, can also be traced to other important observations, one being of a young girl with an exceptional talent for music. Rejecting contemporary notions of cognition, Gall concluded that behavior results from the interaction of a limited set of basic faculties, each with its own processes for perception and memory, each with its own territory in both cerebral or cerebellar cortices. Gall identified 27 faculties, one being the sense of tone relations or music. The description of the latter is identical in both his Anatomie et Physiologie and Sur les Fonctions du Cerveau et sur Celles de Chacune de ses Parties, where he provided positive and negative evidences and discussed findings from humans and lower animals, for the faculty. The localization of the cortical faculty for talented musicians, he explained, is demonstrated by a "bump" on each side of the skull just above the angle of the eye; hence, the lower forehead of musicians is broader or squarer than in other individuals. Additionally, differences between singing and nonsinging birds also correlate with cranial features. Gall even brought age, racial, and national differences into the picture. What he wrote about music reveals much about his science and creative thinking. PMID:25684283

  1. Moths on the Flatbed Scanner: The Art of Joseph Scheer

    PubMed Central

    Buchmann, Stephen L.

    2011-01-01

    During the past decade a few artists and even fewer entomologists discovered flatbed scanning technology, using extreme resolution graphical arts scanners for acquiring high magnification digital images of plants, animals and inanimate objects. They are not just for trip receipts anymore. The special attributes of certain scanners, to image thick objects is discussed along with the technical features of the scanners including magnification, color depth and shadow detail. The work of pioneering scanner artist, Joseph Scheer from New York's Alfred University is highlighted. Representative flatbed-scanned images of moths are illustrated along with techniques to produce them. Collecting and preparing moths, and other objects, for scanning are described. Highlights of the Fulbright sabbatical year of professor Scheer in Arizona and Sonora, Mexico are presented, along with comments on moths in science, folklore, art and pop culture. The use of flatbed scanners is offered as a relatively new method for visualizing small objects while acquiring large files for creating archival inkjet prints for display and sale. PMID:26467835

  2. Strabismus and Micro-Opsoclonus in Machado-Joseph Disease.

    PubMed

    Ghasia, Fatema F; Wilmot, George; Ahmed, Anwar; Shaikh, Aasef G

    2016-08-01

    We describe novel deficits of gaze holding and ocular alignment in patients with spinocerebellar ataxia type 3, also known as Machado-Joseph disease (MJD). Twelve MJD patients were studied. Clinical assessments and quantitative ocular alignment measures were performed. Eye movements were quantitatively assessed with corneal curvature tracker and video-oculography. Strabismus was seen in ten MJD patients. Four patients had mild to moderate intermittent exotropia, three had esotropia, one had skew deviation, one had hypotropia, and one patient had moderate exophoria. Three strabismic patients had V-pattern. Near point of convergence was normal in two out of three patients with exotropia. Gaze holding deficits were also common. Eight patients had gaze-evoked nystagmus, and five had micro-opsoclonus. Other ocular motor deficits included saccadic dysmetria in eight patients, whereas all had saccadic interruption of smooth pursuit. Strabismus and micro-opsoclonus are common in MJD. Coexisting ophthalmoplegia or vergence abnormalities in our patients with exotropia that comprised 50 % of the cohort could not explain the type of strabismus in our patients. Therefore, it is possible that involvement of the brainstem, the deep cerebellar nuclei, and the superior cerebellar peduncle are the physiological basis for exotropia in these patients. Micro-opsoclonus was also common in MJD. Brainstem and deep cerebellar nuclei lesion also explains micro-opsoclonus, whereas brainstem deficits can describe slow saccades seen in our patients with MJD. PMID:26306823

  3. The birth of chronobiology: Julien Joseph Virey 1814.

    PubMed

    Reinberg, A E; Lewy, H; Smolensky, M

    2001-03-01

    Julien-Joseph Virey (1775-1846) held the position of pharmacist-in-chief at the Val-de-Grâce, a military hospital. He was an innovative pharmacist, naturalist, anthropologist, and philosopher and a prolific author. His writings encompassed a wide range of topics, although many of his ideas were sometimes harshly questioned. Interest in Virey's work today stems from renewed appreciation of his doctoral thesis in medicine, which was completed in 1814 in Paris and was the first devoted to biological rhythms. Virey envisioned biological rhythms to be innate in origin and controlled by living clocks entrained by periodic environmental changes, such as the day-night alternation in light and darkness. He also reported that the effects of drugs vary according to their administration time. But, above all, he collected and published quantified time series that demonstrated human circadian and annual mortality rhythms. Statistical analysis of Virey's data using modern time series methods confirms his deduction that human mortality exhibits rhythmicity. Comparison of his findings with those derived from analyses of more recent human mortality time series shows the characteristics of these rhythms have changed little since 1807 despite differences in environmental conditions. Virey deserves credit for establishing the field of chronobiology based on his insights and writings. PMID:11379660

  4. Moths on the Flatbed Scanner: The Art of Joseph Scheer.

    PubMed

    Buchmann, Stephen L

    2011-01-01

    During the past decade a few artists and even fewer entomologists discovered flatbed scanning technology, using extreme resolution graphical arts scanners for acquiring high magnification digital images of plants, animals and inanimate objects. They are not just for trip receipts anymore. The special attributes of certain scanners, to image thick objects is discussed along with the technical features of the scanners including magnification, color depth and shadow detail. The work of pioneering scanner artist, Joseph Scheer from New York's Alfred University is highlighted. Representative flatbed-scanned images of moths are illustrated along with techniques to produce them. Collecting and preparing moths, and other objects, for scanning are described. Highlights of the Fulbright sabbatical year of professor Scheer in Arizona and Sonora, Mexico are presented, along with comments on moths in science, folklore, art and pop culture. The use of flatbed scanners is offered as a relatively new method for visualizing small objects while acquiring large files for creating archival inkjet prints for display and sale. PMID:26467835

  5. Electrical Enlightenment: Joseph Priestley's Historical and Experimental Studies of Electricity

    NASA Astrophysics Data System (ADS)

    Boantza, Victor

    Joseph Priestley (1733-1804) was one of the most controversial public figures of the eighteenth century. A true Enlightenment polymath, he wrote more than two hundred books, pamphlets, sermons, and essays on subjects ranging from science to politics and from metaphysics to theology. He was a religious dissenter, political radical, vocal supporter of the French Revolution, and lifelong defender of the losing side in the Chemical Revolution. Priestley is best known for having ``discovered'' oxygen in the 1770s and for his lasting contributions to pneumatic chemistry. Yet his first scientific fascination, while teaching at Warrington Academy, was electricity--one of the greatest scientific fads of the Enlightenment. Priestley's work on electricity, both historical and experimental, culminated in his History and Present State of Electricity (1767), which became a standard textbook on the subject for nearly a century, and went through numerous editions and translations. Situating Priestley's electrical investigations against the background of eighteenth-century ideals of scientific theory and practice, especially concerning physics, experimental philosophy, and natural history, illuminates the relations between science, society, and epistemology in the Enlightenment.

  6. Notes on Joseph Fraunhofer's honorary Ph.D. degree from Erlangen, 1822 (German Title: Bemerkungen zur Ehrenpromotion Joseph Fraunhofers 1822 in Erlangen )

    NASA Astrophysics Data System (ADS)

    Ventzke, Karl

    In 1822, Joseph Fraunhofer received a honorary Ph.D. degree from Erlangen University. Presumably, this distinction was based on suggestions by Johann Wilhelm Pfaff. Since 1822, Pfaff gave lectures with the inclusion of instruments, which he obtained directly from Fraunhofer, and presumably also included problems of spectral investigation. This contribution analyzes informations which were collected in this regard.

  7. Oral Histories in Meteoritics and Planetary Science - XVII: Joseph Goldstein

    NASA Astrophysics Data System (ADS)

    Sears, Derek W. G.

    2012-05-01

    In this interview, Joseph Goldstein (Fig. 1) recounts how he became interested in meteorites during his graduate studies working with Robert Ogilvie at MIT. By matching the Ni profiles observed across taenite fields in the Widmanstätten structure of iron meteorites with profiles he computed numerically he was able to determine cooling rates as the meteorites cooled through 650-400 °C. Upon graduating, he worked with a team of meteorite researchers led by Lou Walter at Goddard Space Flight Center where for 4 years he attempted to understand metallographic structures by reproducing them in the laboratory. Preferring an academic environment, Joe accepted a faculty position in the rapidly expanding metallurgy department at Lehigh University where he was responsible for their new electron microprobe. He soon became involved in studying the metal from lunar soils and identifying the metallic component from its characteristic iron and nickel compositions. Over the next two decades he refined these studies of Ni diffusion in iron meteorites, particularly the effect of phosphorus in the process, which resulted in superior Fe-Ni-P phase diagrams and improved cooling rates for the iron meteorites. After a period as vice president for research at Lehigh, in 1993 he moved to the University of Massachusetts to serve as dean of engineering, but during these administrative appointments Joe produced a steady stream of scientific results. Joe has served as Councilor, Treasurer, Vice President, and President of the Meteoritical Society. He received the Leonard Medal in 2005, the Sorby Award in 1999, and the Dumcumb Award for in 2008.

  8. The glacial geology of southern St. Joseph County, Michigan

    NASA Astrophysics Data System (ADS)

    Nicks, Linda

    The objective of the dissertation was to map the glacial geology in southern St. Joseph County, Michigan. The surficial geology was divided into three distinct land systems which are moraine, outwash and fan deposits. The Sturgis Moraine is the most prominent feature transecting the study area from east to west. The topography is further dissected by southwest-trending channels interpreted as tunnel channels. Thick accumulations of sand and gravel in the study area indicate that glacial meltwater deposition played a dominant role in shaping the landscape. Based on the relative size of the channels and outwash deposits, the largest contribution from meltwater deposition was from the Saginaw Lobe and the least from the Huron-Erie Lobe. This study also demonstrated that geophysical techniques such as gamma ray logging of domestic water wells, ground penetrating radar and high resolution seismic were useful tools to identify sand, gravel and clay in the subsurface and the thickness of these units. Seven subsurface, gamma ray log markers could be traced throughout the study area. The gamma ray log markers were calibrated to four continuous cores from Sturgis. The lowest marker, the Sturgis till, lies above a buried soil of possible Sangamon age and is interpreted as a late Wisconsin till. It is present in all wells that are drilled to an adequate depth. Directly overlying the Sturgis till (between markers F--G), is a thin diamicton of similar color but different clay mineralogy (between markers E--F). This thin diamicton is variable in thickness and sometimes there is a facies change from diamicton to coarser grained material at the same stratigraphic level. This sequence is overlain by a sequence of sand and gravel (between markers A and E). This coarse grained sequence is sometimes punctuated by a sequence (or sequences) of higher gamma ray counts interpreted as finer grained units and these individual markers can be traced throughout the study area (markers A

  9. Cytokines in Machado Joseph Disease/Spinocerebellar Ataxia 3.

    PubMed

    da Silva Carvalho, Gerson; Saute, Jonas Alex Morales; Haas, Clarissa Branco; Torrez, Vitor Rocco; Brochier, Andressa Wigner; Souza, Gabriele Nunes; Furtado, Gabriel Vasata; Gheno, Tailise; Russo, Aline; Monte, Thais Lampert; Schumacher-Schuh, Artur; D'Avila, Rui; Donis, Karina Carvalho; Castilhos, Raphael Machado; Souza, Diogo Onofre; Saraiva-Pereira, Maria Luiza; Torman, Vanessa Leotti; Camey, Suzi; Portela, Luis Valmor; Jardim, Laura Bannach

    2016-08-01

    The aim of the present study is to describe the serum concentrations of a broad spectrum of cytokines in symptomatic and asymptomatic carriers of Machado Joseph disease (SCA3/MJD) CAG expansions. Molecularly confirmed carriers and controls were studied. Age at onset, disease duration, and clinical scales Scale for the Assessment and Rating of Ataxia (SARA), Neurological Examination Score for Spinocerebellar Ataxias (NESSCA), SCA Functional Index (SCAFI), and Composite Cerebellar Functional Score (CCFS) were obtained from the symptomatic carriers. Serum was obtained from all individuals and a cytokine panel "consisted of" eotaxin, granulocyte-macrophage colony-stimulating factor (GM-CSF), interferon (IFN)-α, IFN-γ, interleukin (IL)-1β, IL-1RA, IL-2, IL-2R, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12, IL-13, IL-15, IL-17, interferon gamma-induced protein (IP)-10, monocyte chemoattractant protein (MCP)-1, monokine induced by gamma interferon (MIG), macrophage inflammatory protein (MIP)-a, MIP-b, regulated on activation, normal T cell expressed and secreted (RANTES) and tumor necrosis factor (TNF)-α was analyzed. In a subgroup of symptomatic carriers, the cytokine panel was repeated after 360 days. Cytokine distribution among groups was studied by discriminant analysis; changes in serum levels after 360 days were studied by generalized estimation equation. Sixty-six symptomatic carriers, 13 asymptomatic carriers, and 43 controls were studied. No differences in cytokine patterns were found between controls and carriers of the CAG expansions or between controls and symptomatic carriers only. In contrast, eotaxin concentrations were significantly higher in asymptomatic than in symptomatic carriers or in controls (p = 0.001, ANCOVA). Eotaxin did not correlate with age, disease duration, CAG expansion, NESSCA score, and SARA score. Among symptomatic carriers, eotaxin dropped after 360 days (p = 0.039, GEE). SCA3/MJD patients presented a benign pattern of

  10. Machado-Joseph Disease: from first descriptions to new perspectives

    PubMed Central

    2011-01-01

    Machado-Joseph Disease (MJD), also known as spinocerebellar ataxia type 3 (SCA3), represents the most common form of SCA worldwide. MJD is an autosomal dominant neurodegenerative disorder of late onset, involving predominantly the cerebellar, pyramidal, extrapyramidal, motor neuron and oculomotor systems; although sharing features with other SCAs, the identification of minor, but more specific signs, facilitates its differential diagnosis. MJD presents strong phenotypic heterogeneity, which has justified the classification of patients into three main clinical types. Main pathological lesions are observed in the spinocerebellar system, as well as in the cerebellar dentate nucleus. MJD's causative mutation consists in an expansion of an unstable CAG tract in exon 10 of the ATXN3 gene, located at 14q32.1. Haplotype-based studies have suggested that two main founder mutations may explain the present global distribution of the disease; the ancestral haplotype is of Asian origin, and has an estimated age of around 5,800 years, while the second mutational event has occurred about 1,400 years ago. The ATXN3 gene encodes for ataxin-3, which is ubiquitously expressed in neuronal and non-neuronal tissues, and, among other functions, is thought to participate in cellular protein quality control pathways. Mutated ATXN3 alleles consensually present about 61 to 87 CAG repeats, resulting in an expanded polyglutamine tract in ataxin-3. This altered protein gains a neurotoxic function, through yet unclear mechanisms. Clinical variability of MJD is only partially explained by the size of the CAG tract, which leaves a residual variance that should be explained by still unknown additional factors. Several genetic tests are available for MJD, and Genetic Counseling Programs have been created to better assist the affected families, namely on what concerns the possibility of pre-symptomatic testing. The main goal of this review was to bring together updated knowledge on MJD, covering

  11. BOOK REVIEW: Joseph Henry: The Rise of an American Scientist

    NASA Astrophysics Data System (ADS)

    Crawford, Elspeth

    1998-09-01

    Albert Moyer has clearly done his research into the events of Joseph Henry's life. The personal, professional, sociological and scientific aspects have been meticulously detailed throughout and the ordering, as in the chapter headings, is chronological, so that there is some element of each of these aspects in each chapter. This is unfortunately both the strength and the weakness of the biography, as the detail seemed to me to be the most remarkable characteristic of the writing. But, the bigger stories, or the themes, which might have been possible, seemed to get lost. Hence, I found this a book for those who are seriously interested in Joseph Henry; but for those whose interest might be more general, say having an interest in nineteenth century growth of scientific institutions, or wanting to understand the conceptual development of electromagnetism, there seemed to be too much which came from the Henry point of view, rather than locating Henry within his time and context. This is a remark about style, rather than omission of content, as the myriad of details in each paragraph certainly inform the reader about the context. For instance, some sociology of the USA in the nineteenth century could be inferred, say showing how a young man from a modest background might make his way into a professional life, but the information is so particularly a description of Henry's experience that one has to rely on prior knowledge or make assumptions in order to create a sociological perspective. That is, I now know, what happened to Henry, but I do not know if his case was in any sense typical or atypical. Similarly there is information about education in general at that time, and scientific education, research and its publication, as it applied to Henry. The relationships between science in the USA and in Europe have a place, and there is quite a bit of information about the institutions in which Henry worked, particularly Albany Academy, Princeton and the Smithsonian. Henry

  12. BOOK REVIEW: Joseph Henry: The Rise of an American Scientist

    NASA Astrophysics Data System (ADS)

    Crawford, Elspeth

    1998-09-01

    Albert Moyer has clearly done his research into the events of Joseph Henry's life. The personal, professional, sociological and scientific aspects have been meticulously detailed throughout and the ordering, as in the chapter headings, is chronological, so that there is some element of each of these aspects in each chapter. This is unfortunately both the strength and the weakness of the biography, as the detail seemed to me to be the most remarkable characteristic of the writing. But, the bigger stories, or the themes, which might have been possible, seemed to get lost. Hence, I found this a book for those who are seriously interested in Joseph Henry; but for those whose interest might be more general, say having an interest in nineteenth century growth of scientific institutions, or wanting to understand the conceptual development of electromagnetism, there seemed to be too much which came from the Henry point of view, rather than locating Henry within his time and context. This is a remark about style, rather than omission of content, as the myriad of details in each paragraph certainly inform the reader about the context. For instance, some sociology of the USA in the nineteenth century could be inferred, say showing how a young man from a modest background might make his way into a professional life, but the information is so particularly a description of Henry's experience that one has to rely on prior knowledge or make assumptions in order to create a sociological perspective. That is, I now know, what happened to Henry, but I do not know if his case was in any sense typical or atypical. Similarly there is information about education in general at that time, and scientific education, research and its publication, as it applied to Henry. The relationships between science in the USA and in Europe have a place, and there is quite a bit of information about the institutions in which Henry worked, particularly Albany Academy, Princeton and the Smithsonian. Henry

  13. [The vitalism of Paul-Joseph Barthez (1734-1806)].

    PubMed

    Han, Hee Jin

    2010-06-30

    In The Logic of Life (1970), Francois Jacob (1920- ), Nobel Prize laureate in Physiology or Medicine (1965), proclaimed the end of vitalism based on the concept of life. More than two decades before this capital sentence condemning vitalism was pronounced, Georges Canguilhem (1904-1995), a French philosopher of medicine, already acknowledged that eighteenth-century vitalism was scientifically retrograde and politically reactionary or counter-revolutionary insofar as it was rooted in the animism of Georg Ernst Stahl (1660-1734). The negative preconception of the term 'vitalism' came to be established as an orthodox view, since Claude Bernard (1813-1878) unfairly criticized contemporary vitalism in order to propagate his idea of experimental medicine. An eminent evolutionary biologist like Ernst Mayr (1904-2005) still defended similar views in This is Biology (1997), arguing that if vitalists were decisive and convincing in their rejection of the Cartesian model (negative heuristics), however they were equally indecisive and unconvincing in their own explanatory endeavors (positive heuristics). Historically speaking, vitalists came to the forefront for their outstanding criticism of Cartesian mechanism and physicochemical reductionism, while their innovative concepts and theories were underestimated and received much less attention. Is it true that vitalism was merely a pseudo-science, representing a kind of romanticism or mysticism in biomedical science? Did vitalists lack any positive heuristics in their biomedical research? Above all, what was actually the so.called 'vitalism'? This paper aims to reveal the positive heuristics of vitalism defined by Paul.Joseph Barthez (1734-1806) who was the founder of the vitalist school of Montpellier. To this end, his work and idea are introduced with regard to the vying doctrines in physiology and medicine. At the moment when he taught at the medical school of Montpellier, his colleagues advocated the mechanism of Rene

  14. Joseph McCabe: A Forgotten Early Populariser of Science and Defender of Evolution

    ERIC Educational Resources Information Center

    Cooke, Bill

    2010-01-01

    Joseph McCabe (1867-1955) was one of the most prolific and gifted polymaths of the twentieth century. Long before such a thing was thought respectable, and almost a century before any university established a chair in the public understanding of science, McCabe made a living as a populariser of science and a critic of philosophical and religious…

  15. Factors Influencing Nutrient Losses from Agriculture in the St. Joseph River Watershed, Northeast Indiana

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Nutrient losses from agricultural watersheds in Indiana have been implicated in the hypoxic zone in the Gulf of Mexico as well as massive algal blooms in Lake Erie. We monitored water quality from fields and drainage ditches in the St. Joseph River Watershed, Northeast Indiana. The complex ‘pot-ho...

  16. Joseph Ames's "Typographical Antiquities" and the Antiquarian Tradition

    ERIC Educational Resources Information Center

    Shiner, Elaine

    2013-01-01

    One of the most famous historical documents of English printing is Joseph Ames's "Typographical Antiquities," published in London in 1749. Although Ames referred to his work as a history of printing, the bulk of it is a list of the first printers in England and their works through 1600, with very full bibliographical descriptions…

  17. Joseph Walker, a Black Playwright, Exhorts Counselors and Black People to Deal With Themselves

    ERIC Educational Resources Information Center

    Walker, Joseph

    1976-01-01

    This is an interview with Joseph Walker, black playwright. He attempts to reflect back to the black community their experience in a white controlled world. In this interview, he discusses his views of the black experience, the pressures on man-woman relationships, and the role of black psychiatry. (NG)

  18. Astronauts Joseph Allen rides cherry picker over stowage area/work station

    NASA Technical Reports Server (NTRS)

    1984-01-01

    Astronaut Joseph P. Allen rides a cherry picker over to a stowage area/work station to wrap up extravehicular activity (EVA) duties above Earth. The cherry picker is a union of the mobile foot restraint and the remote manipulator system (RMS), controlled from inside Discovery's cabin. The Westar VI/PAM-D satellite is pictured secured in Discovery's cargo bay.

  19. Exceptional Scholarship and Democratic Agendas: Interviews with John Goodlad, John Hoyle, Joseph Murphy, and Thomas Sergiovanni

    ERIC Educational Resources Information Center

    Mullen, Carol A.

    2006-01-01

    This portraiture study of four exceptional scholars in education--John Goodlad, John Hoyle, Joseph Murphy, and Thomas Sergiovanni--provides insight into their scholarly work and life habits, direction and aspirations, assessment and analysis of major trends in the profession, and advice for aspiring leaders and academics. Telephone interviews with…

  20. Exceptional Scholarship and Democratic Agendas: Interviews with John Goodlad, John Hoyle, Joseph Murphy, and Thomas Sergiovanni

    ERIC Educational Resources Information Center

    Mullen, Carol A.

    2009-01-01

    This portraiture study of four exceptional scholars in education--John Goodlad, John Hoyle, Joseph Murphy, and Thomas Sergiovanni--provides insight into their scholarly work and life habits, direction and aspirations, assessment and analysis of major trends in the profession, and advice for aspiring leaders and academics. Telephone interviews with…

  1. The St. Joseph River Watershed CEAP Project: Highlights of Recent Refocusing of Our Efforts

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Monitoring in the St. Joseph River watershed was initiated in 2002. Over the last six years, the focus has been on monitoring surface runoff from fields and discharge from drainage ditches and a natural stream. The watershed lies in one of the areas of the country with the greatest density of subs...

  2. The Joseph Bellamy House: Great Awakening in Puritan New England. Teaching with Historic Places.

    ERIC Educational Resources Information Center

    Pape, Barbara Bradbury

    The small rural town of Bethlehem, Connecticut, contains pristine examples of modest 18th-century houses that surround a charming village green. Opposite the village green, the Reverend Joseph Bellamy's immense white clapboard house rises from a hilltop, an imposing presence that makes the village appear diminutive. The house stands today as a…

  3. 75 FR 63801 - Action Affecting Export Privileges; Joseph Piquet and Related Person Alphatronx, Inc.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-18

    ... individual Joseph Piquet (``Piquet'') on May 28, 2010 (75 FR 32742, June 9, 2010) applicable to Alphatronx... August 12, 2010 (75 FR 50,681 (Aug. 16, 2010)), has continued the Regulations in effect under the... published in the Federal Register on June 9, 2010 at 75 FR 32742, shall be made applicable to...

  4. A Short Biography of Joseph Fourier and Historical Development of Fourier Series and Fourier Transforms

    ERIC Educational Resources Information Center

    Debnath, Lokenath

    2012-01-01

    This article deals with a brief biographical sketch of Joseph Fourier, his first celebrated work on analytical theory of heat, his first great discovery of Fourier series and Fourier transforms. Included is a historical development of Fourier series and Fourier transforms with their properties, importance and applications. Special emphasis is made…

  5. What's in a Coauthor?: (Re)Locating Joseph Denney in Composition History

    ERIC Educational Resources Information Center

    Davis, Ivan

    2012-01-01

    This article reassesses the Fred Newton Scott and Joseph Villiers Denney collaborative textbook authorship by emphasizing Denney's generally overlooked contributions to that coauthorship and to the field of composition generally. Through an examination of Denney's scholarly work and his personal correspondence with Scott during the period marking…

  6. Ethnographic Research and Globalization: A Discussion of Joseph Tobin's Model of Video-Cued Multivocal Ethnography

    ERIC Educational Resources Information Center

    Watras, Joseph

    2014-01-01

    Joseph Tobin made an impact on the field of comparative education in 2009 when he used a unique form of ethnography to illuminate the effects of world-wide forces, such as modernization, on schools in specific countries. Earlier, in 1989, he published "Preschool in Three Cultures" with co-authors David Wu and Dana Davidson. The…

  7. Joseph Priestley Is the Focus as Modern Chemistry Celebrates Its Second Century

    ERIC Educational Resources Information Center

    Bernheim, Robert A.; Olofson, Roy A.

    1974-01-01

    This article describes a meeting in 1874, seen to be the origin of the American Chemical Society, which commemorated the 100th anniversary of Joseph Priestley's discovery of oxygen. The remainder of the article is concerned with Priestley's scientific contributions and their implications. (DT)

  8. Joseph Pulitzer II and Advertising Censorship, 1929-1939. Journalism Monographs Number Seventy-seven.

    ERIC Educational Resources Information Center

    Pfaff, Daniel W.

    In an age of little or no consumer protection, the St. Louis "Post-Dispatch," under the guidance of Joseph Pulitzer II, was the first and most successful practitioner of self-imposed censorship of advertising, a practice that continues to this day. Beginning on May 1, 1929, the "Post-Dispatch" announced an aggressive program of advertising…

  9. Assessing conservation effects on water quality in the St. Joseph River Watershed

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Agriculture is a major contributor to non-point source pollution of streams, rivers and lakes. The St. Joseph River is a major drinking water source in northeastern Indiana that has been contaminated by chemicals in runoff. A Source Water Protection Initiative project began in 2002, with the focus ...

  10. Highlighting High Performance Buildings: Adam Joseph Lewis Center for Environmental Studies

    SciTech Connect

    2002-11-01

    Oberlin College's Adam Joseph Lewis Center for Environmental Studies is a high-performance building featuring an expansive photovoltaic system and a closed-loop groundwater heat pump system. Designers incorporated energy-efficient components and materials that are local, non-toxic, and durable.

  11. The Plight of the American Writer and Joseph Brodsky in Exile.

    ERIC Educational Resources Information Center

    Updike, John; Jacoby, Susan

    1994-01-01

    Two articles originally published in the 1970s are reprinted. The first argues that the American writer no longer knows what is expected of him and has difficulty engaging in conversation with the reader. The second examines the work and teaching of Joseph Brodsky, a Russian poet, while in the United States. (MSE)

  12. General Education Assessment and Fulfilling the Mercy Mission at the University of Saint Joseph

    ERIC Educational Resources Information Center

    Callahan, Kevin J.

    2014-01-01

    This article describes the processes and procedures the University of Saint Joseph used to conduct a systematic assessment of mission-related student-learning outcomes found in the General Education curriculum, and thus assess how well the institution was fulfilling its Mercy mission. The assessment showed student learning strengths and gaps and…

  13. Recent theoretical chemical dynamics at Rochester in the paths of Joseph O. Hirschfelder

    NASA Technical Reports Server (NTRS)

    George, T. F.; Lam, K.-S.; Bhattacharyya, D. K.; Hutchinson, M.; Zimmerman, I. H.; Devries, P. L.; Yuan, J.-M.

    1982-01-01

    A review of recent theoretical studies of gas-phase molecular rate processes, including various effects of laser radiation, is presented in the context of the extensive and influential work of Joseph O. Hirschfelder during the past half-century. The topics addressed are energy transfer, chemical reactions, unimolecular dissociation, transition states, and bound-continuum interactions.

  14. Joseph Woolley--Pioneer of British Naval Education; 1848-1879

    ERIC Educational Resources Information Center

    Dickinson, H. W.

    2007-01-01

    For almost 25 years Joseph Woolley served the Admiralty as a teacher, inspector of schools and as the first Admiralty Director of Education. Despite the fact that Woolley held this post for a decade, that he was the sole occupant in the nineteenth century and that in this capacity he gave evidence to, or was a member of, every government committee…

  15. 46 CFR 45.183 - Load line requirements for the St. Joseph and Muskegon routes.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 2 2013-10-01 2013-10-01 false Load line requirements for the St. Joseph and Muskegon routes. 45.183 Section 45.183 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LOAD LINES GREAT LAKES LOAD LINES Unmanned River Barges on Lake Michigan Routes § 45.183 Load...

  16. 46 CFR 45.183 - Load line requirements for the St. Joseph and Muskegon routes.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 2 2012-10-01 2012-10-01 false Load line requirements for the St. Joseph and Muskegon routes. 45.183 Section 45.183 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LOAD LINES GREAT LAKES LOAD LINES Unmanned River Barges on Lake Michigan Routes § 45.183 Load...

  17. 46 CFR 45.183 - Load line requirements for the St. Joseph and Muskegon routes.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Load line requirements for the St. Joseph and Muskegon routes. 45.183 Section 45.183 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LOAD LINES GREAT LAKES LOAD LINES Unmanned River Barges on Lake Michigan Routes § 45.183 Load...

  18. 46 CFR 45.183 - Load line requirements for the St. Joseph and Muskegon routes.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 2 2011-10-01 2011-10-01 false Load line requirements for the St. Joseph and Muskegon routes. 45.183 Section 45.183 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LOAD LINES GREAT LAKES LOAD LINES Unmanned River Barges on Lake Michigan Routes § 45.183 Load...

  19. 46 CFR 45.183 - Load line requirements for the St. Joseph and Muskegon routes.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 2 2014-10-01 2014-10-01 false Load line requirements for the St. Joseph and Muskegon routes. 45.183 Section 45.183 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LOAD LINES GREAT LAKES LOAD LINES Unmanned River Barges on Lake Michigan Routes § 45.183 Load...

  20. Constructing Secret Rooms: Assemblages, Creative Writing, Self-discovery, and the Art of Joseph Cornell.

    ERIC Educational Resources Information Center

    Platt, Thomas Julian

    1998-01-01

    Profiles a course that challenges college seniors to gain new perspectives, skills, experiences, and insights into their own creative and imaginative processes. The course uses the work of Joseph Cornell who constructed enigmatic, box-like assemblages from found objects. Students construct their own boxes and consider future applications of this…

  1. Astronaut Joseph Tanner checks gloves during during launch/entry training

    NASA Technical Reports Server (NTRS)

    1994-01-01

    Astronaut Joseph R. Tanner, mission specialist, checks his gloves during a rehearsal for the launch and entry phases of the scheduled November 1994 flight of STS-66. This rehearsal, held in the crew compartment trainer (CCT) of JSC's Shuttle mockup and integration laboratory, was followed by a training session on emergency egress procedures.

  2. Riotous Images: Representations of Joseph Priestley in British Prints during the French Revolution

    ERIC Educational Resources Information Center

    Clay, Richard

    2008-01-01

    This article focuses on printed images that were published in Britain during the 1790s, depicting the educationist, theologian, chemist, physicist, historian and philosopher Joseph Priestley (1733-1804). It is argued that such etchings and engravings are indicative of, and contributed to, the lifelong political and historical education of late…

  3. A Curriculum for Character Education: Joseph Schwab and the Ramah Camps

    ERIC Educational Resources Information Center

    Cohen, Burton; Pereira, Peter; Roby, Thomas; Block, Alan

    2005-01-01

    Joseph Schwab (1909-1988) is known for his scathing critique of curriculum theory and its over reliance on quantitative models derived from social science theories. From the late 1950's through the middle 1960's, Schwab was instrumental to efforts to create a new and more educationally sound curriculum for weekday religious schools in synagogues…

  4. Conceiving of Concept Maps to Foster Meaningful Learning: An Interview with Joseph D. Novak

    ERIC Educational Resources Information Center

    Cardellini, Liberato

    2004-01-01

    Joseph Novak discusses the concept of mapping to capture and archive expert knowledge. He worked in various corporations where he used the concept of mapping for research and development efforts and to create and transfer knowledge and information in corporate environments.

  5. The Oral History of Evaluation: The Professional Development of Joseph Wholey

    ERIC Educational Resources Information Center

    Miller, Robin Lin; Caracelli, Valerie

    2013-01-01

    Joseph S. Wholey is Professor Emeritus in the University of Southern California's (USC) School of Public Policy, Planning, and Development. He received his BA from Catholic University, Phi Beta Kappa and his MA in mathematics and PhD in philosophy from Harvard University. His work focuses on the use of strategic planning, performance measurement,…

  6. Toward a Telic Vision of Human Beings: A Dialogue with Joseph F. Rychlak.

    ERIC Educational Resources Information Center

    Howard, George S.

    1987-01-01

    Presents interview with Joseph F. Rychlak on topics of notions of causality in science, relationship of research to practice in humanistic psychology, research evidence for a telic view of human action, counseling active agents, choice and free will, and philosophy of science and humanisitic theory. (ABL)

  7. From Chemical Analysis to Analyzing Chemical Education: An Interview with Joseph J. Lagowski

    ERIC Educational Resources Information Center

    Cardellini, Liberato

    2010-01-01

    This interview provides glimpses of Joseph J. Lagowski and his life from the time he played with a Gilbert chemistry set, to his tenure at The University of Texas at Austin. His initial interest in chemistry was further nurtured and developed thanks to an excellent high school teacher. In the interview, Lagowski discusses his research in…

  8. Psi Chi/APA Edwin B. Newman Graduate Research Award: Joseph H. Hammer

    ERIC Educational Resources Information Center

    American Psychologist, 2009

    2009-01-01

    Joseph H. Hammer, recipient of the Psi Chi/APA Edwin B. Newman Graduate Research Award, is cited for an outstanding research paper whose findings provide important evidence regarding the promise of a male-sensitive approach to mental health marketing and empirically support the inclusion of theory-driven enhancements in group-targeted mental…

  9. Painting as Rhetorical Performance: Joseph Wright's "An Experiment on a Bird in the Air Pump."

    ERIC Educational Resources Information Center

    Helmers, Marguerite

    2001-01-01

    Explores three broad areas of inquiry: what significance visual images have for rhetorical analysis; how a study of nonverbal material might be conducted; and whether visual explanations depend on the image or the viewer. Argues that viewers understand Joseph Wright's painting "The Air Pump" in terms of its subject, its exhibition space, the…

  10. Speaking Frankly on the Sexual Behavior of Children--Joseph D. Noshpitz.

    ERIC Educational Resources Information Center

    Long, Nichloas J., Ed.

    1998-01-01

    With the passing of Joseph D. Noshpitz, the field of troubled youth lost a distinguished leader. A founding member of the American Academy of Child and Adolescent Psychiatry, Noshpitz leaves a legacy of pivotal publications. Describes Noshpitz's contributions and shares one of his classic and once-censored articles on sexuality in children.…

  11. Wildlife Habitat Impact Assessment, Chief Joseph Dam Project, Washington : Project Report 1992.

    SciTech Connect

    Kuehn, Douglas; Berger, Matthew

    1992-01-01

    Under the Pacific Northwest Electric Power Planning and Conservation Act of 1980, and the subsequent Northwest Power Planning Council`s Columbia River Basin Fish and Wildlife Program, a wildlife habitat impact assessment and identification of mitigation objectives have been developed for the US Army Corps of Engineer`s Chief Joseph Dam Project in north-central Washington. This study will form the basis for future mitigation planning and implementation.

  12. Astronaut Joseph Kerwin during EVA at Skylab 1 and 2 space station cluster

    NASA Technical Reports Server (NTRS)

    1973-01-01

    Scientist-Astronaut Joseph P. Kerwin, Skylab 2 science pilot, performs extravehicular activity (EVA) at the Skylab 1 and 2 space station cluster in Earth orbit, as seen in this reproduction taken from a color television transmission made by a TV camera aboard the station. Kerwin is just outside the Airlock Module. Kerwin assisted Astronaut Charles Conrad Jr., Skylab 2 commander, during the successful EVA attempt to free the stuck solar array system wing on the Orbital Workshop.

  13. Administration of Vincristine in a Patient with Machado-Joseph Disease

    PubMed Central

    Colpo, Anna; Wilson, Frederick H.; Nardi, Valentina; Hochberg, Ephraim

    2012-01-01

    Chemotherapy-induced peripheral neurotoxicity is a major problem because it represents the dose-limiting side effect of a significant number of antineoplastic drugs, such as vinca alkaloids. Hereditary neuropathies usually predispose to severe vincristine neurotoxicity. Here, we report the case of a 56-year-old man with Machado-Joseph disease, also known as spinocerebellar ataxia type 3, treated with a vinca alkaloid without exacerbation of neurological symptoms. PMID:22433430

  14. Arthur Conan Doyle, Joseph Bell, and Sherlock Holmes. A neurologic connection.

    PubMed

    Westmoreland, B F; Key, J D

    1991-03-01

    Neurologists, like physicians in several other medical specialties, can lay claim to Sherlock Holmes as one of their own. This assertion is validated by the number of neurologic conditions, such as seizures, stroke, syncope, encephalopathies, and head trauma, that are mentioned in the stories and novels. In addition, the article reviews the powers of observation and the deductive approach utilized by Conan Doyle and Joseph Bell, the models for Sherlock Holmes, and how these skills can be applied to medical problems. PMID:2001191

  15. Re-establishing ataxin-2 downregulates translation of mutant ataxin-3 and alleviates Machado-Joseph disease.

    PubMed

    Nóbrega, Clévio; Carmo-Silva, Sara; Albuquerque, David; Vasconcelos-Ferreira, Ana; Vijayakumar, Udaya-Geetha; Mendonça, Liliana; Hirai, Hirokazu; de Almeida, Luís Pereira

    2015-12-01

    Machado-Joseph disease is a progressive neurodegenerative disorder associated with the polyQ-expanded ataxin-3 (encoded by ATXN3), for which no therapy is available. With the aim of clarifying the mechanism of neurodegeneration, we hypothesized that the abnormally long polyQ tract would interact aberrantly with ataxin-2 (encoded by ATXN2), another polyQ protein whose function has recently been linked to translational regulation. Using patient's samples and cellular and animal's models we found that in Machado-Joseph disease: (i) ataxin-2 levels are reduced; and (ii) its subcellular localization is changed towards the nucleus. Restoring ataxin-2 levels by lentiviral-mediated overexpression: (i) reduced mutant ataxin-3 levels; and (ii) rescued behaviour defects and neuropathology in a transgenic mouse model of Machado-Joseph disease. Conversely (i) mutating the ataxin-2 motif that enables binding to its natural interactor and translation activator poly(A)-binding protein; or (ii) overexpressing poly(A)-binding protein, had opposite effects, increasing mutant ataxin-3 translation and aggregation. This work suggests that in Machado-Joseph disease, mutant ataxin-3 drives an abnormal reduction of ataxin-2 levels, which overactivates poly(A)-binding protein, increases translation of mutant ataxin-3 and other proteins and aggravates Machado-Joseph disease. Re-establishment of ataxin-2 levels reduces mutant ataxin-3 and alleviates Machado-Joseph disease pathogenesis opening a new avenue for therapeutic intervention in this and potentially other polyQ disorders. PMID:26490332

  16. Machado–Joseph disease in a Nigerian family: mutational origin and review of the literature

    PubMed Central

    Ogun, Shamsideen Abayomi; Martins, Sandra; Adebayo, Philip B; Dawodu, Clara O; Sequeiros, Jorge; Finkel, Michael F

    2015-01-01

    Machado–Joseph disease (MJD) has been described in Africans, but no cases have been reported from Nigeria. Current MJD global distribution results from both the ancestral populations-of-origin and the founder effects of mutations, some as a consequence of the Portuguese sea travels in the 15th to 16th century. Two main ancestral haplotypes have been identified: the Machado lineage, which is more recent, predominant in families of Portuguese extraction, and the Joseph lineage, which is much older and worldwide spread, postulated to have an Asian origin. We report a Nigerian family with MJD from Calabar, once settled by Portuguese slave traders, and assessed its mutational origin. The proband was a 33-year-old man with progressive unsteady gait, weakness of all limbs, dysphagia, dysarthria, urinary frequency and diaphoresis. He had end-of-gaze nystagmus, spastic quadriparesis and atrophic small muscles of the hand. He showed fibrillation potentials on EMG, and nerve conduction studies suggested a central axonopathy without demyelination. This family bears the Joseph haplotype, which has a founder effect in the island of Flores, in the Azores (and their descendants in North-America), but is also the most common in non-Portuguese populations worldwide, with an estimated mutation age of around 7000 years. PMID:24781759

  17. Joseph Warren: a discussion of his life and analysis of his death.

    PubMed

    Holland, Ryan; Sabourin, Victor M; Gandhi, Chirag D; Carmel, Peter W; Prestigiacomo, Charles J

    2015-07-01

    As his fellow soldiers ran past him, Joseph Warren stood bravely on Bunker Hill. It was June 17, 1775, and British troops were fighting the colonists in one of the early battles of the American Revolution. The British had already attempted two major assaults that day, and the third would end with Warren's death. He was a medical doctor, public figure, and general who spent his life and last living moments fighting for freedom for the American colonists. After the battle, there was much confusion about what had happened to Joseph Warren. Some thought he had survived the battle; other accounts differed on how exactly he had died. The details of the events on Bunker Hill remained a mystery until the following year, when Paul Revere helped identify Warren's body by the false teeth that had been implanted years earlier. Warren's remains showed that his head had been struck by a bullet. Analysis of the skull helped to sift through the differing tales of Warren's death and thus unveil the truth about what occurred that day. The smaller bullet wound in the left maxilla suggests that he was not shot while retreating with the rest of the soldiers. The larger exit wound in the right occiput illustrates that the bullet's trajectory crossed the midline of the brain and most likely injured the brainstem. Therefore, contrary to rumors that circulated at the time, Joseph Warren most likely was killed instantly at the Battle of Bunker Hill while heroically facing his enemy. PMID:26126399

  18. A 325-year reconstruction of St. Joseph River streamflow using tree rings

    NASA Astrophysics Data System (ADS)

    Schmidt, Karly R.

    The use of tree ring widths as indicators of water resource availability affords annual-scale resolution in the reconstruction of streamflow prior to the limited instrumental record. While an abundance of streamflow reconstructions have been conducted in the western United States, few have been undertaken in the eastern half of the country. This study aims to enhance understanding of regional hydroclimate in the Great Lakes region by presenting a 325-year streamflow reconstruction for the St. Joseph River, as well as contributing two new tree ring-width chronologies in Indiana and Michigan. A variety of factors potentially influencing the chance of successful streamflow reconstruction are also posited and discussed. A total of 55 tree ring width chronologies from Indiana, Illinois, Michigan, Wisconsin, and Ontario were examined using standard methods in dendrochronology and nested principal component analysis (PCA) to reconstruct St. Joseph River streamflow to 1675 with greater skill than climatology. The resulting overall reconstruction and periods identified as severe droughts and pluvials were in general agreement with other dendroclimatological studies in the eastern U.S. The findings suggest that the instrumental record (beginning in 1924) does not accurately depict long-term streamflow variability of the St. Joseph River. The reconstructed values tend to overestimate the intensity and duration of pluvial periods, but also show that droughts in the region were of similar intensity to those in the more recent past, but were of longer duration. This suggests that water resource managers may need to consider a wider range of variability than previously indicated by the instrumental record.

  19. The Forgotten Forefather: Joseph James Kinyoun and the Founding of the National Institutes of Health

    PubMed Central

    Morens, David M.; Fauci, Anthony S.

    2012-01-01

    ABSTRACT In celebrating the 125th anniversary of the National Institutes of Health (NIH) in August 2012, NIH has been examining its origins, its history, and the visionary men and women whose research have contributed to the saving and/or improving the quality of life of millions of people throughout the world. This minireview examines Joseph James Kinyoun (1860 to 1919), the 1887 founder of a federal Hygienic Laboratory that is considered the direct ancestor of the modern NIH, and explores the development of NIH as it was shaped by, and in turn shaped, the new field of microbiology. PMID:22736540

  20. Li-Fraumeni syndrome: Discovery and future challenges - Joseph Fraumeni Symposium

    Cancer.gov

    In May 2014, NCI’s Division of Cancer Epidemiology and Genetics (DCEG) hosted Cancer Epidemiology: From Pedigrees to Populations, a scientific symposium honoring 50 years of visionary leadership by Dr. Joseph F. Fraumeni, Jr., the founding Director of DCEG. In this video, Dr. Stephen Chanock of NCI provides opening remarks. Dr. David Schottenfeld of the University of Michigan moderates a session on the search for cancer susceptibility genes. Dr. Louise Strong of University of Texas MD Anderson Cancer Center speaks about the discovery and future challenges of Li-Fraumeni syndrome research. For more information on this symposium, visit http://dceg.cancer.gov/news-events/Fraumeni-symposium-speakers.

  1. Decoupling the Stationary Navier-Stokes-Darcy System with the Beavers-Joseph-Saffman Interface Condition

    DOE PAGESBeta

    Cao, Yong; Chu, Yuchuan; He, Xiaoming; Wei, Mingzhen

    2013-01-01

    This paper proposes a domain decomposition method for the coupled stationary Navier-Stokes and Darcy equations with the Beavers-Joseph-Saffman interface condition in order to improve the efficiency of the finite element method. The physical interface conditions are directly utilized to construct the boundary conditions on the interface and then decouple the Navier-Stokes and Darcy equations. Newton iteration will be used to deal with the nonlinear systems. Numerical results are presented to illustrate the features of the proposed method.

  2. Joseph Daquin, Piedmontese Savoyard physician, a "not well-known chiarugi".

    PubMed

    Vanni, D; Salomone, B; Pomini, D; Vanni, P; Ottaviani, R

    1999-06-01

    We present a critical review of La philosophie de la folie, second edition, published in 1804. Joseph Daquin's thoughts and clinical activity in the psychiatric field are described. Daquin's ideas about various forms of madness and the different therapeutic, moral, physical treatments, his anatomical studies, successes and failures are presented. Several clinical cases are described. The author's view of the moon's influence on madness is described. Finally it is shown how very important was the human person and the moral treatment of madness for Daquin, in contrast with the current opinion at the end of 1700. PMID:11623834

  3. Sustainable Planning Practices in St. Joseph Watershed as a Mixed Land-Use Watershed to Reduce the Risk of Chemical Impairment of Surface Water Supplies

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Increased population growth in St. Joseph Watershed and the mix of land-use with urban and agricultural production brings about chemical impairment of metropolitan drinking water supplies. Furthermore, the St. Joseph Watershed is not only a drinking water supply, but also it provides water for recre...

  4. 75 FR 50010 - Atchison Casting Corp. (n/k/a Bradken-Atchison/St. Joseph, Inc.), CityFed Financial Corp., Divine...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-16

    ... COMMISSION Atchison Casting Corp. (n/k/a Bradken-Atchison/St. Joseph, Inc.), CityFed Financial Corp., Divine, Inc. (n/k/a Enivid, Inc.), Genesis Worldwide, Inc., Hampton Consulting Corp., and Jake's Pizza... Casting Corp. (n/k/a Bradken-Atchison/St. Joseph, Inc.) because it has not filed any periodic...

  5. [A missing name in the history of chagasic megaesophagus: Joseph Cooper Reinhardt (1809/10-1873)].

    PubMed

    Meneghelli, U G; de Rezende, J M; Troncon, L E; Madrid, N; de Moura, M L

    1998-01-01

    The book entitled "Brazil and the Brasilians", written by the Reverends Kidder and Fletcher and firstly published in the United States in 1857, reports the travels of these two missionaries throughout Brazil and includes a section entitled "A new disease". This section contains data regarding the clinical picture, the natural history and the epidemiology of a commom disease in Brazilian hinterland, which was known as "mal de engasgo". These informations were collected in 1855 by Rev. Fletcher from an anonymous North American physician, who worked in Limeira, State of São Paulo, and is called in the book merely as "Dr.-". The present work reports the results of an investigation carried out aiming at the identification of "Dr.-" and discloses documental evidence that "Dr.-" was actually Dr. Joseph Cooper Reinhardt (1809/10-1883). Dr. Reinhardt worked for many years in the citites of Limeira and Campinas, State of São Paulo, and probably had an extensive knowledge regarding the main features of this particular disease, which would be known, nearly 100 years later, as chagasic megaesophagus. The authors point out that, from now on, any account of the history of chagasic megaesophagus must include the name of Dr. Joseph Cooper Reinhardt. PMID:9711306

  6. Agricultural land use and water quality in the upper St. Joseph River basin, Michigan

    USGS Publications Warehouse

    Cummings, T. Ray

    1978-01-01

    Land use in the upper St. Joseph River basin of south-central Michigan is primarily agricultural. In the 144-square-mile area, the chemical and physical characteristics of water are determined by the climate and soils, as well as by land conservation practices. Municipal waste discharges affect water quality at some locations, as do the larger lakes and ponds. Data indicate that mean discharge from the basin is 135 cubic feet per second. About half this flow is contributed to the St. Joseph River by three major tributaries: Beebe Creek (36 cubic feet per second); Sand Creek (24 cubic feet per second); and Soap Creek (13 cubic feet per second). Runoff from 21 drainage areas delineated for the investigation ranged from 0.22 to 4.07 cubic feet per second per square mile; both the higher and lower values are largely the result of naturally occurring inter- and intrabasin transfers of water. Suspended-sediment concentrations are low throughout the basin, rarely exceeding 100 milligrams per liter. Mean concentrations at four daily sampling stations on the major tributaries and on the St. Joseph River ranged from 9.7 milligrams per liter to 38 milligrams per liter. The maximum sediment yield was 182 pounds per acre per year. Deposition of sediment in five of the 21 areas resulted in a net loss of sediment transported, and thus ?negative? yields. Nitrogen and phosphorus concentrations do not vary greatly from site to site. Mean concentrations of total nitrogen at downstream sites on Beebe, Sand, and Soap Creeks, and on the St. Joseph River ranged from 1.5 to 1.8 milligrams per liter. About 90 percent of all nitrogen, and 66 percent of all phosphorus, is transported in solution. Land used principally for agriculture has a mean total nitrogen yield of 4.9 pounds per acre per year and a mean total phosphorus yield of 0.13 pounds per year. A comparison of total nitrogen and total phosphorus yields with type of agricultural use showed few relationships; nitrogen yield, however

  7. Building a Comprehensive Watershed-Scale Project for Assessing Conservation Effects at the St Joseph River Watershed

    Technology Transfer Automated Retrieval System (TEKTRAN)

    In 2002, we began a Source Water Protection Initiative project in the St Joseph River Watershed at northeast Indiana, USA. The initial focus was to evaluate existing and innovative agricultural practices in reducing pesticides, specifically atrazine, loadings to the source water for the City of Ft ...

  8. Effects of Agricultural and Conservation Practices on Nutrients Losses from the St. Joseph River Watershed, Northeast Indiana

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Agriculture has been identified as a primary contributor to nutrients that cause algal blooms in the Gulf of Mexico and Lake Erie. Since 2002, we have been monitoring water quality from agricultural drainage ditches in the St. Joseph River watershed to assess the impacts of agricultural and conserva...

  9. 77 FR 49835 - Order Prohibiting Involvement in NRC-Licensed Activities; In the Matter of Mr. Joseph Quintanilla

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-17

    ... rule (72 FR 49139; August 28, 2007). The E-Filing process requires participants to submit and serve all... COMMISSION Order Prohibiting Involvement in NRC-Licensed Activities; In the Matter of Mr. Joseph Quintanilla.... Quintanilla indicated that he was aware the camera was outside of the dark room and did not contest...

  10. 75 FR 76052 - Southern Nuclear Operating Company, Inc. Joseph M. Farley Nuclear Plant, Units 1 and 2; Exemption

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-07

    ... environment (75 FR 73135, dated November 29, 2010). This exemption is effective upon issuance. Dated at... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Southern Nuclear Operating Company, Inc. Joseph M. Farley Nuclear Plant, Units 1 and 2;...

  11. Joseph V. Denney, the Land-Grant Mission, and Rhetorical Education at Ohio State: An Institutional History

    ERIC Educational Resources Information Center

    Mendenhall, Annie S.

    2011-01-01

    This essay provides an account of The Ohio State University's (OSU) rhetoric department during the tenure of Joseph Villiers Denney, arguing that he appropriated and repurposed national trends in education and rhetoric in ways that complicate the narrative of rhetoric and composition's decline in the late nineteenth century. In this essay, the…

  12. Research Administration in History: The Development of OMB Circular A-110 through Joseph Warner's COGR Subcommittee, 1976-1979

    ERIC Educational Resources Information Center

    Myers, Phillip E.; Smith, Marie F.

    2008-01-01

    Research administrators can be assisted in resolving issues with awareness of the critical period of policy formation divulged in the Joseph Warner Papers. He and his colleagues on the Subcommittee on Grants and Contracts Provisions of COGR adopted the philosophy that research administrators needed flexibility and reduced paperwork and costs.…

  13. Defining American Heroes: Analyzing the Metamorphosis of the War Hero in Twentieth Century War Films Using Joseph Campbell's, "Hero's Journey."

    ERIC Educational Resources Information Center

    Frith, Luci A.

    In "The Hero's Journey" Joseph Campbell identifies the patterns that inform the myths of the "hero" throughout recorded history. By using Campbell's template, this paper examines how the American war hero is portrayed and has been portrayed in film. The paper states that Americans not only define their war heroes in films but also use these film…

  14. Use of surface and borehole geophysics to delineate the glacial-drift stratigraphy of northeastern St. Joseph County, Indiana

    USGS Publications Warehouse

    Bayless, E. Randall; Westjohn, David B.; Watson, Lee R.

    1995-01-01

    Inverse models of direct current electrical- resistivity sounding data and normal-resistivity and natural-gamma logs were used to assist delineation of the glacial-drift stratigraphy in a 580-square- kilometer area of northeastern St. Joseph County, Indiana. Unconsolidated deposits in the study area are composed of glacial-drift, including outwash, till, and lacustrine sediments; thicknesses range from about 15 to more than 70 meters. The glacial outwash deposits are mostly composed of sand and gravel and are the primary source of drinking water to northeastern St. Joseph County. The glacial till and glacio-lacustrine deposits contain a larger fraction of clay than the outwash deposits and may retard ground-water flow between shallow and deeper sand and gravel aquifers. Results of the geophysical measurements collected during this study indicate that glacial-drift deposits in the area north and east of the St. Joseph River are mostly composed of sand and gravel with inter-layered clay-rich deposits that are laterally discontinuous. In the area south of the St. Joseph River, the thickness of sand and gravel deposits diminishes, and clay-rich deposits dominate the stratigraphy. The presence of an electrically conductive bedrock, the Ellsworth Shale, beneath the glacial-drift deposits is identified in inverse models of direct current electrical-resistivity sounding data.

  15. 77 FR 61657 - Indiana Northeastern Railroad Company-Abandonment Exemption-In Branch and St. Joseph Counties, MI

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-10

    ... St. Joseph Counties, MI Indiana Northeastern Railroad Company (IN) has filed a verified notice of... between milepost 81.32 near Coldwater in Branch County, Mich., and milepost 100.69 near Sturgis in St.... Rail Lines, 5 I.C.C. 2d 377 (1989). Any request for a stay should be filed as soon as possible so...

  16. RNA Interference Mitigates Motor and Neuropathological Deficits in a Cerebellar Mouse Model of Machado-Joseph Disease

    PubMed Central

    Onofre, Isabel; Albuquerque, David; Déglon, Nicole; Pereira de Almeida, Luís

    2014-01-01

    Machado-Joseph disease or Spinocerebellar ataxia type 3 is a progressive fatal neurodegenerative disorder caused by the polyglutamine-expanded protein ataxin-3. Recent studies demonstrate that RNA interference is a promising approach for the treatment of Machado-Joseph disease. However, whether gene silencing at an early time-point is able to prevent the appearance of motor behavior deficits typical of the disease when initiated before onset of the disease had not been explored. Here, using a lentiviral-mediated allele-specific silencing of mutant ataxin-3 in an early pre-symptomatic cerebellar mouse model of Machado-Joseph disease we show that this strategy hampers the development of the motor and neuropathological phenotypic characteristics of the disease. At the histological level, the RNA-specific silencing of mutant ataxin-3 decreased formation of mutant ataxin-3 aggregates, preserved Purkinje cell morphology and expression of neuronal markers while reducing cell death. Importantly, gene silencing prevented the development of impairments in balance, motor coordination, gait and hyperactivity observed in control mice. These data support the therapeutic potential of RNA interference for Machado-Joseph disease and constitute a proof of principle of the beneficial effects of early allele-specific silencing for therapy of this disease. PMID:25144231

  17. The Interaction of Physics, Mechanics and Mathematics in Joseph Liouville's Research

    NASA Astrophysics Data System (ADS)

    Lützen, Jesper

    As many of his contemporaries did, Joseph Liouville often emphasized the importance of physics for mathematical research. His own works provide a host of examples of interactions between mathematics and physics. This paper analyses some of them. It is shown how Laplacian physics gave rise to Liouville's theory of differentiation of arbitrary order, how Kelvin's research on electrostatics gave rise to Liouville's theorem about conformal mappings and how the theory of heat conduction gave rise to Sturm-Liouville theory. It will be shown how the problem of the shape of the planets was an important inspiration for Liouville's far reaching studies of Lamé functions and spectral theory of a particular type of integral operators. Finally the interactions between Liouville's work on mechanics and differential geometry will be discussed.

  18. [Savants and cultutal boundaries. Thermalism in Savoy and the work of Joseph Daquin (1732-1815)].

    PubMed

    Carpanetto, Dino

    2008-01-01

    The essay sets out to explain the general orientation of the studies, the problems, the perspectives and the research that were done by Joseph Daquin (1732-1815), a physician born in Chambéry (Savoy, Kingdom of Sardinia). He had a secular education at the Faculty of Medicine of Turin, where he earned his degree under Ignazio Somis and Vitaliano Donati. The aim of this essay is to give a critical contribution to cultural history and examine the origins of thermalism with particular emphasis on therapy, physics experiments, and its relation to political and social structure. Daquin was a witness of the advancement of science beyond the boundaries of scientific Enlightenment. His overriding intellectual concern was with the meaning and impact of chemistry theories on medical practices. The author has published an interesting Analyse des eaux thermales d'Aix en Savoie (1773), a natural experimental history of mineral waters in Aix-les-Bains. PMID:19378865

  19. Cost analysis of magnetic resonance imaging at St. Joseph's Health Centre of London.

    PubMed Central

    Reese, L

    1987-01-01

    In April 1986 St. Joseph's Health Centre of London, Ont., completed 3 years of operating a magnetic resonance imaging unit. The first 2 years were devoted to research and development. From Apr. 1, 1985, to Mar. 31, 1986, the unit operated as the first clinical service unit in Canada. Over the 12 months 1671 patients (an average of 9 patients per 12-hour day) were examined. Studies of the brain (62%) and the spine (21%) accounted for most of the procedures. The operating costs for the year were $892,000; revenues totalled $449,000, for a deficit of $443,000. The average technical cost per patient was $534. Increasing the number of patients examined per year would lower the cost to $431. PMID:3815214

  20. The fate of the bird specimens from Cook's voyages possessed by Sir Joseph Banks.

    PubMed

    Medway, David G

    2009-10-01

    Joseph Banks possessed the greater part of the zoological specimens collected on James Cook's three voyages round the world (1768-1780). In early 1792, Banks divided his zoological collection between John Hunter and the British Museum. It is probable that those donations together comprised most of the zoological specimens then in the possession of Banks, including such bird specimens as remained of those that had been collected by himself and Daniel Solander on Cook's first voyage, and those that had been presented to him from Cook's second and third voyages. The bird specimens included in the Banks donations of 1792 became part of a series of transactions during the succeeding 53 years which involved the British Museum, the Royal College of Surgeons of England, and William Bullock. It is a great pity that, of the extensive collection of bird specimens from Cook's voyages once possessed by Banks, only two are known with any certainty to survive. PMID:20014506

  1. A Science Superior to Music: Joseph Sauveur and the Estrangement between Music and Acoustics

    NASA Astrophysics Data System (ADS)

    Fix, Adam

    2015-09-01

    The scientific revolution saw a shift from the natural philosophy of music to the science of acoustics. Joseph Sauveur (1653-1716), an early pioneer in acoustics, determined that science as understood in the eighteenth century could not address the fundamental problems of music, particularly the problem of consonance. Building on Descartes, Mersenne, and Huygens especially, Sauveur drew a sharp divide between sound and music, recognizing the former as a physical phenomenon obeying mechanical and mathematical principles and the latter as an inescapably subjective and unquantifiable perception. While acoustics grew prominent in the Académie des sciences, music largely fell out of the scientific discourse, becoming primarily practiced art rather than natural philosophy. This study illuminates what was considered proper science at the dawn of the Enlightenment and why one particular branch of natural philosophy—music—did not make the cut.

  2. Sir Edward Appleton and Joseph Priestley: two giants of electrical science

    NASA Astrophysics Data System (ADS)

    Excell, P. S.

    The life of Sir Edward Appleton is reviewed, in commemoration of the recent centenary of his birth. Appleton discovered the ionosphere and devoted much of his life to investigations of its properties, receiving the Nobel Prize for physics as a result. He became a senior government scientist in World War II and afterwards was appointed Vice-Chancellor of Edinburgh University. The influence of his roots in the city of Bradford is emphasized and compared with the case of Joseph Priestley, also born near Bradford some 160 yr earlier. Priestley was a major early investigator of electrical phenomena and compiled a comprehensive treatise on the electrical knowledge of his day. He was the first person to present an experimental proof of the inverse-square law of electrostatic force, although he is usually better remembered as the discoverer of oxygen.

  3. Sympathetic science: Charles Darwin, Joseph Hooker, and the passions of Victorian naturalists.

    PubMed

    Endersby, Jim

    2009-01-01

    This essay examines the complex tangle of emotional and scientific attachments that linked Darwin and botanist Joseph Dalton Hooker. Analyzing their roles as husbands, fathers, and novel readers demonstrates that possessing and expressing sympathy was as important for Victorian naturalists as it was for Victorian husbands. Sympathy was a scientific skill that Victorian naturalists regarded as necessary to fully understand the living world; although sympathy became increasingly gendered as feminine over the course of the century, its importance to male naturalists requires us to rethink the ways gender roles were negotiated in Victorian Britain. Botany was, for men like Darwin and Hooker, an acceptably masculine pursuit that nevertheless allowed--and even required--them to be sensitive and sympathetic. PMID:19824199

  4. A life more ordinary: the dull life but interesting times of joseph dalton hooker.

    PubMed

    Endersby, Jim

    2011-01-01

    The life of Joseph Dalton Hooker (1817-1911) provides an invaluable lens through which to view mid-Victorian science. A biographical approach makes it clear that some well-established narratives about this period need revising. For example, Hooker's career cannot be considered an example of the professionalisation of the sciences, given the doubtful respectability of being paid to do science and his reliance on unpaid collectors with pretensions to equal scientific and/or social status. Nor was Hooker's response to Darwin's theories either straightforward or contradictory; it only makes sense as carefully crafted equivocation when seen in the context of his life and career. However, the importance of Hooker's life is ultimately its typicality; what was true of Hooker was true of many other Victorian men of science. PMID:21336663

  5. Jacques-Joseph Ébelmen, the founder of earth system science

    NASA Astrophysics Data System (ADS)

    Berner, Robert A.

    2012-11-01

    The fundamental principles of the factors affecting the global carbon cycle, the global sulfur cycle and the levels of atmospheric CO2 and O2 over long-term (multimillion year) time scales were first elucidated by Jacques-Joseph Ébelmen in 1845. He covered all major processes in such a correct manner that no appreciable changes in them have been elucidated since then. Unfortunately, his ideas were forgotten and were independently deduced by others only 100 to 150 years later. In this article, his reasoning is shown in detail, via a number of original quotations, and the results of a mathematical model by the author for CO2 and O2 over the Phanerozoic Eon (past 542 million years) are presented. In agreement with Ébelmen's predictions, there apparently have been large changes in the levels of atmospheric CO2 and O2 over geologic time.

  6. Squamous Cell Carcinoma Arising in a Testicular Teratoma and Presenting as Sister Mary Joseph Nodule

    PubMed Central

    Khan, Kalyan; Bagchi, Dibakar

    2011-01-01

    The most common somatic type malignancy arising in patients with testicular germ cell tumors (GCTs) is sarcoma. Development of carcinomas, especially squamous cell carcinoma is an extremely rare event. Most cases of metastatic umbilical nodules (Sister Mary Joseph nodule) develop from adenocarcinomas. Fifteen percent of such cases have unknown origin; but development from a testicular squamous cell carcinoma has not yet been reported in the literature. We report a rare case of somatic type squamous cell carcinoma arising in a testicular teratoma. It is also possibly the first reported case of its kind which presented with a metastatic umbilical nodule. This possibility should be kept in mind while evaluating metastatic umbilical nodules in young male patients. PMID:22413055

  7. Joseph McCabe: A Forgotten Early Populariser of Science and Defender of Evolution

    NASA Astrophysics Data System (ADS)

    Cooke, Bill

    2010-05-01

    Joseph McCabe (1867-1955) was one of the most prolific and gifted polymaths of the twentieth century. Long before such a thing was thought respectable, and almost a century before any university established a chair in the public understanding of science, McCabe made a living as a populariser of science and a critic of philosophical and religious obscurantism. Through the first half of the twentieth century he wrote countless cheap and widely distributed books and pamphlets for those whose thirst for knowledge exceeded the money or time they could devote to such pursuits. This article will detail, and give some assessment of, McCabe’s career as a populariser of science and expositor of evolutionary theory and its philosophical, religious and cultural ramifications.

  8. Conceiving of Concept Maps To Foster Meaningful Learning: An Interview with Joseph D. Novak

    NASA Astrophysics Data System (ADS)

    Cardellini, Liberato

    2004-09-01

    Joseph Novak, the inventor of concept maps, explains in this interview how that idea was born thirty years ago. As a student he developed a passion for education, trying to find better ways to educate people and help them "learn how to learn". Concept maps can profitably be used to represent knowledge in every field of study: they help students to construct new learning and are also useful for teachers to discover possible misconceptions in the students' own construction. Novak discusses the advantages of meaningful learning and the foundations of his theory of education based on "human constructivism" and he summarizes it in a concept map. He also explains why concept maps are a useful tool for corporations, too.

  9. The Wichita Valley irrigation project: Joseph Kemp, boosterism, and conservation in northwest Texas, 1886-1939.

    PubMed

    Anderson, Jahue

    2011-01-01

    This is the story of failure: in this case, an irrigation project that never met its boosters' expectations. Between 1880 and 1930, Wichita Falls entrepreneur Joseph Kemp dreamed of an agrarian Eden on the Texas rolling plains. Kemp promoted reclamation and conservation and envisioned the Big Wichita River Valley as the "Irrigated Valley." But the process of bringing dams and irrigation ditches to the Big Wichita River ignored knowledge of the river and local environment, which ultimately was key to making these complex systems work. The boosters faced serious ecological limitations and political obstacles in their efforts to conquer water, accomplishing only parts of the grandiose vision. Ultimately, salty waters and poor drainage doomed the project. While the livestock industry survived and the oil business thrived in the subsequent decades, the dream of idyllic irrigated farmsteads slowly disappeared. PMID:22180941

  10. Sir Joseph Barcroft: one victorian physiologist's contributions to a half century of discovery.

    PubMed

    Longo, Lawrence D

    2016-03-01

    During the first half of the 20th Century, Joseph Barcroft, KBE, FRS of Cambridge University became a world leader in respiratory physiology. He determined the role of neural stimulation in the oxygen consumption of several organs, established many of the factors that regulate the binding of oxygen to haemoglobin, explored the determinants of a human's acclimatization to high altitude and developed the field of fetal cardiovascular physiology. Chair of the Cambridge Department of Physiology from 1925 to 1937, he served as a consultant and member of many UK governmental committees. During World War I, he led a British research unit exploring the effects of poisonous gases on pulmonary function and related problems. In addition to his almost 300 publications, several of his monographs are considered as classics. PMID:25929679

  11. Review of the hydrologic data-collection network in the St Joseph River basin, Indiana

    USGS Publications Warehouse

    Crompton, E.J.; Peters, J.G.; Miller, R.L.; Stewart, J.A.; Banaszak, K.J.; Shedlock, R.J.

    1986-01-01

    The St. Joseph River Basin data-collection network in the St. Joseph River for streamflow, lake, ground water, and climatic stations was reviewed. The network review included only the 1700 sq mi part of the basin in Indiana. The streamflow network includes 11 continuous-record gaging stations and one partial-record station. Based on areal distribution, lake effect , contributing drainage area, and flow-record ratio, six of these stations can be used to describe regional hydrology. Gaging stations on lakes are used to collect long-term lake-level data on which to base legal lake levels, and to monitor lake-level fluctuations after legal levels are established. More hydrogeologic data are needed for determining the degree to which grouhd water affects lake levels. The current groundwater network comprises 15 observation wells and has four purposes: (1) to determine the interaction between groundwater and lakes; (2) to measure changes in groundwater levels near irrigation wells; (3) to measure water levels in wells at special purpose sites; and (4) to measure long-term changes in water levels in areas not affected by pumping. Seven wells near three lakes have provided sufficient information for correlating water levels in wells and lakes but are not adequate to quantify the effect of groundwater on lake levels. Water levels in five observation wells located in the vicinity of intensive irrigation are not noticeably affected by seasonal withdrawals. The National Weather Sevice operates eight climatic stations in the basin primarily to characterize regional climatic conditions and to aid in flood forecasting. The network meets network-density guidelines established by the World Meterological Organization for collection of precipitation and evaporation data but not guidelines suggested by the National Weather Service for density of precipitation gages in areas of significant convective rainfalls. (Author 's abstract)

  12. Resident Fish Stock Status above Chief Joseph and Grand Coulee Dams; 2000 Annual Report.

    SciTech Connect

    Crossley, Brian; Lockwood, Jr., Neil W.; McLellan, Jason G.

    2001-01-01

    The Resident Fish Stock Status above Chief Joseph and Grand Coulee Dams Project, commonly known as the Joint Stock Assessment Project (JSAP) is a management tool using ecosystem principles to manage artificial fish assemblages and native fish in altered environments existing in the Columbia River System above Chief Joseph and Grand Coulee Dams (blocked area). The three-phase approach of this project will enhance the fisheries resources of the blocked area by identifying data gaps, filling data gaps with research, and implementing management recommendations based on research results. The Blocked Area fisheries information housed in a central location will allow managers to view the entire system while making decisions, rather than basing management decisions on isolated portions of the system. The JSAP (NWPPC program measure 10.8B.26) is designed and guided jointly by fisheries managers in the blocked area and the Columbia Basin blocked area management plan (1998). The initial year of the project (1997) identified the need for a central data storage and analysis facility, coordination with the StreamNet project, compilation of blocked area fisheries information, and a report on the ecological condition of the Spokane River System. These needs were addressed in 1998 by acquiring a central location with a data storage and analysis system, coordinating a pilot project with StreamNet, compiling fisheries distribution data throughout the blocked area, identifying data gaps based on compiled information, and researching the ecological condition of the Spokane River. In order to ensure that any additional information collected throughout the life of this project will be easily stored and manipulated by the central storage facility, it was necessary to develop standardized methodologies between the JSAP fisheries managers. The use of common collection and analytical tools is essential to the process of streamlining joint management decisions. In 1999 and 2000 the project

  13. A short biography of Joseph Fourier and historical development of Fourier series and Fourier transforms

    NASA Astrophysics Data System (ADS)

    Debnath, Lokenath

    2012-07-01

    The profound study of nature is the most fertile source of mathematical discoveries. Not only does this study, by offering a definite goal to research, have the advantage of excluding vague questions and futile calculations, but it is also a sure means of moulding analysis itself, and discerning those elements in it which it is still essential to know and which science ought to conserve. These fundamental elements are those which recur in all natural phenomena. Joseph Fourier pure mathematics enables us to discover the concepts and laws connecting them, which gives us the key to the understanding of the phenomena of nature. Albert Einstein This article deals with a brief biographical sketch of Joseph Fourier, his first celebrated work on analytical theory of heat, his first great discovery of Fourier series and Fourier transforms. Included is a historical development of Fourier series and Fourier transforms with their properties, importance and applications. Special emphasis is made to his splendid research contributions to mathematical physics, pure and applied mathematics and his unprecedented public service accomplishments in the history of France. This is followed by historical comments about the significant and major impact of Fourier analysis on mathematical physics, probability and mathematical statistics, mathematical economics and many areas of pure and applied mathematics including geometry, harmonic analysis, signal analysis, wave propagation and wavelet analysis. Special attention is also given to the Fourier integral formula, Brownian motion and stochastic processes and many examples of applications including isoparametric inequality, everywhere continuous but nowhere differentiable functions, Heisenberg uncertainty principle, Dirichlets' theorem on primes in

  14. Sister Mary Joseph Nodule as a First Manifestation of a Metastatic Ovarian Cancer

    PubMed Central

    Ogino, Mai; Kinuta, Takatoshi; Hori, Masateru; Mori, Tatsuo

    2016-01-01

    A 76-year-old female presented to our hospital with a 2 cm firm, nontender, protuberant umbilical nodule. She received treatment with antibiotics for suspected granuloma, with no improvement after two months. High levels of CA125 as well as an ovarian cyst and intrathoracic and intra-abdominal lesions on imaging studies made us suspect an ovarian cancer with a Sister Mary Joseph nodule (SMJN) and other metastases. A bilateral salpingo-oophorectomy and umbilical and omentum tumor resections were performed and a metastatic ovarian serous adenocarcinoma was diagnosed by histopathology. After surgery, the patient received chemotherapy with paclitaxel, carboplatin, and bevacizumab; however paclitaxel allergy was observed. As a result, chemotherapy continued with carboplatin and bevacizumab every three weeks for a total of 6 courses. Currently, she is still undergoing treatment with bevacizumab and CA125 levels have been progressively decreasing. SMJN is a rare umbilical metastasis which needs to be considered as a differential diagnosis in the presence of an umbilical tumor for prompt treatment initiation.

  15. Traces of the Past: Unraveling the Secrets of Archaeology through Chemistry (by Joseph B. Lambert)

    NASA Astrophysics Data System (ADS)

    Orna, Mary Virginia

    1998-07-01

    Addison-Wesley: Reading, MA, 1997. 319 pp. 9.5 x 6.4 in. ISBN 0201409283. $30.00. One of the most fascinating ideas in science is the Heisenberg uncertainty principle. How can science, which is so highly regarded for its ability to present irrefutable evidence, be based at its core on uncertainty? The answer, of course, lies in the notion that any probe that is inserted into a system in order to perform a measurement will necessarily change that system, however slightly. So it is with analytical chemistry as it turns its observer's eye on the problems of the past: archaeological chemists, in the very act of analyzing and examining the mysteries of our cultural origins and artifacts, have indeed, by becoming part of the system being observed, changed and even created major sectors of our culture. And no author has been more successful than Joseph B. Lambert in documenting and demonstrating with many fascinating examples how this cultural examination and creation has evolved.

  16. Joseph Erlanger (1874-1965): the cardiovascular investigator who won a Nobel Prize in neurophysiology.

    PubMed

    Breathnach, Caoimhghín S; Moynihan, John B

    2014-11-01

    Born in San Francisco in 1874 into the family of German immigrants in which he was the only one to proceed beyond elementary education, Joseph Erlanger graduated from the University of California (Berkeley) in 1894. He was about to enter the local Cooper Medical School when he was told that the new medical school in Johns Hopkins University (Baltimore) aimed to surpass all others, and there he graduated and was later coached for a career in academic life by William H Howell (1860-1945). In due course he held the Chairs of Physiology in the University of Wisconsin (Madison) and Washington University at St Louis, Missouri. He showed that the Bundle of His is indeed the functional link between the atria and the ventricles in the mammalian heart and that the Korotkoff sounds are produced by a 'breaker' phenomenon resulting from instability of the pulse wave in a partially occluded artery. With Herbert S Gasser (1888-1963) he was awarded the Nobel Prize in 1944 for their work on action currents in peripheral nerve fibres. The history of science occupied him during his retirement. He died at St Louis in 1965. PMID:24585622

  17. Joseph John Thomson's models of matter and radiation in the early 1890s.

    PubMed

    Bordoni, Stefano

    In the late nineteenth century, Joseph John Thomson moved away from Maxwell's specific theoretical models of matter and energy, even though he continued to rely on the general framework of Maxwell's electromagnetic theory. In his 1893 book, he accomplished the conceptual drift towards a discrete model for matter, electricity, and fields. In Thomson's model, energy was linked to tubes of force, in particular to the aether contained in them and surrounding them: the energy was the kinetic energy of aether, of both a rotational and translational kind. Starting from Maxwell's electromagnetic fields, namely stresses propagating through a continuous solid medium, Thomson arrived at a representation of fields as a sea of discrete units carrying energy and momentum. He tried to transform Maxwell's theory into a unified picture in which atomic models of matter stood beside atomic models of fields. In 1904 his interpretation of X-rays was based on the integration between two complementary features of electromagnetic radiation, the continuity and the discreteness, and on some kind of fibrous aether. In recent secondary literature, the problematic conceptual link between J. J. Thomson's theory and contemporary theories on electromagnetic radiation has been underestimated. On the contrary, in the first half of the twentieth century, some physicists inquired into that link, and a widespread debate emerged, misunderstandings included. PMID:25029824

  18. Correlation between CAG repeat length and clinical features in Machado-Joseph disease

    SciTech Connect

    Maciel, P.; Gaspar, C.; Silveira, I.

    1995-07-01

    Machado-Joseph disease (MJD) is associated with the expansion of a CAG trinucleotide repeat in a novel gene on 14q32.1. We confirmed the presence of this expansion in 156 MJD patients from 33 families of different geographic origins: 15 Portuguese Azorean, 2 Brazilian, and 16 North American of Portuguese Azorean descent. Normal chromosomes contain between 12 and 37 CAG repeats in the MJD gene, whereas MJD gene carriers have alleles within the expanded range of 62-84 CAG units. The distribution of expanded alleles and the gap between normal and expanded allele sizes is either inconsistent with a premutation hypothesis or most (if not all) of the alleles we studied descend from a common ancestor. There is a strong correlation between the expanded repeat size and the age at onset of the disease as well as the clinical presentation. There is mild instability of the CAG tract length with transmission of the expanded alleles; both increase and decrease in size between parents and progeny occur, with larger variations in male than in female transmissions. Together, these effects can partly explain the variability of age at onset and of phenotypic features in MJD; however, other modifying factors must exist. 37 refs., 6 figs.

  19. Joseph Black, carbon dioxide, latent heat, and the beginnings of the discovery of the respiratory gases.

    PubMed

    West, John B

    2014-06-15

    The discovery of carbon dioxide by Joseph Black (1728-1799) marked a new era of research on the respiratory gases. His initial interest was in alkalis such as limewater that were thought to be useful in the treatment of renal stone. When he studied magnesium carbonate, he found that when this was heated or exposed to acid, a gas was evolved that he called "fixed air" because it had been combined with a solid material. He showed that the new gas extinguished a flame, that it could not support life, and that it was present in gas exhaled from the lung. Within a few years of his discovery, hydrogen, nitrogen, and oxygen were also isolated. Thus arguably Black's work started the avalanche of research on the respiratory gases carried out by Priestley, Scheele, Lavoisier, and Cavendish. Black then turned his attention to heat and he was the first person to describe latent heat, that is the heat added or lost when a liquid changes its state, for example when water changes to ice or steam. Latent heat is a key concept in thermal physiology because of the heat lost when sweat evaporates. Black was a friend of the young James Watt (1736-1819) who was responsible for the development of early steam engines. Watt was puzzled why so much cooling was necessary to condense steam into water, and Black realized that the answer was the latent heat. The resulting improvements in steam engines ushered in the Industrial Revolution. PMID:24682452

  20. Limited Effect of Chronic Valproic Acid Treatment in a Mouse Model of Machado-Joseph Disease

    PubMed Central

    Esteves, Sofia; Duarte-Silva, Sara; Naia, Luana; Neves-Carvalho, Andreia; Teixeira-Castro, Andreia; Rego, Ana Cristina; Silva-Fernandes, Anabela; Maciel, Patrícia

    2015-01-01

    Machado-Joseph disease (MJD) is an inherited neurodegenerative disease, caused by a CAG repeat expansion within the coding region of ATXN3 gene, and which currently lacks effective treatment. In this work we tested the therapeutic efficacy of chronic treatment with valproic acid (VPA) (200mg/kg), a compound with known neuroprotection activity, and previously shown to be effective in cell, fly and nematode models of MJD. We show that chronic VPA treatment in the CMVMJD135 mouse model had limited effects in the motor deficits of these mice, seen mostly at late stages in the motor swimming, beam walk, rotarod and spontaneous locomotor activity tests, and did not modify the ATXN3 inclusion load and astrogliosis in affected brain regions. However, VPA chronic treatment was able to increase GRP78 protein levels at 30 weeks of age, one of its known neuroprotective effects, confirming target engagement. In spite of limited results, the use of another dosage of VPA or of VPA in a combined therapy with molecules targeting other pathways, cannot be excluded as potential strategies for MJD therapeutics. PMID:26505994

  1. War, sanity, and the Nazi mind: the last passion of Joseph Jastrow.

    PubMed

    Behrens, Peter J

    2009-11-01

    The career of Joseph Jastrow (1863-1944) spanned more than 50 years in service to psychology. For 40 years he represented academic psychology at the University of Wisconsin as chair of the psychology department (1886 to 1927), but also was never far from popularizing psychology through books, articles, public lectures, newspaper columns, and finally radio lectures (e.g., Jastrow, 1900, 1935b). Providing a scientific and progressive psychology for the general public was always a strong penchant for Jastrow on several subjects, such as spiritualism (Jastrow, 1911) and effective living (Jastrow, 1935b). About 1939, while he was well into his 70s, his efforts focused on exposing the menace that Adolf Hitler and Nazism posed, so he undertook to enlist prominent editors to publish his work, Hitler: Mask and Myth, as articles or a book. He was not successful in gaining support for the project. His failing can be understood from the perspectives of the American market for Hitler material, the shortcomings of the manuscript, and how he represented psychology to the American public. PMID:20509353

  2. Correlation between CAG Repeat Length and Clinical Features in Machado-Joseph Disease

    PubMed Central

    Maciel, Patrícia; Gaspar, Claudia; DeStefano, Anita L.; Silveira, Isabel; Coutinho, Paula; Radvany, João; Dawson, David M.; Sudarsky, Lewis; Guimarães, João; Loureiro, Jose E. L.; Nezarati, Marjan M.; Corwin, Lee I.; Lopes-Cendes, Iscia; Rooke, Karen; Rosenberg, Roger; MacLeod, Patrick; Farrer, Lindsay A.; Sequeiros, Jorge; Rouleau, Guy A.

    1995-01-01

    Machado-Joseph disease (MJD) is associated with the expansion of a CAG trinucleotide repeat in a novel gene on 14q32.1. We confirmed the presence of this expansion in 156 MJD patients from 33 families of different geographic origins: 15 Portuguese Azorean, 2 Brazilian, and 16 North American of Portuguese Azorean descent. Normal chromosomes contain between 12 and 37 CAG repeats in the MJD gene, whereas MJD gene carriers have alleles within the expanded range of 62–84 CAG units. The distribution of expanded alleles and the gap between normal and expanded allele sizes is either inconsistent with a premutation hypothesis or most (if not all) of the alleles we studied descend from a common ancestor. There is a strong correlation between the expanded repeat size and the age at onset of the disease as well as the clinical presentation. There is mild instability of the CAG tract length with transmission of the expanded alleles; both increase and decrease in size between parents and progeny occur, with larger variations in male than in female transmissions. Together, these effects can partly explain the variability of age at onset and of phenotypic features in MJD; however, other modifying factors must exist. ImagesFigure 3 PMID:7611296

  3. Resident Fish Stock Status above Chief Joseph and Grand Coulee Dams; 2001 Annual Report.

    SciTech Connect

    Connor, Jason M.; McLellan, Jason G.; O'Connor, Dick

    2003-01-01

    In 1980, the United States Congress enacted the Northwest Power Planning and Conservation Act (PL 96-501, 1980), which established the Northwest Power Planning Council (NPPC). The NPPC was directed by Congress to develop a regional Power Plan and also the Columbia River Basin Fish and Wildlife Program (FWP) to restore or replace losses of fish caused by construction and operation of hydroelectric dams in the Columbia River Basin. In developing the FWP, Congress specifically directed NPPC to solicit recommendations for measures to be included in the Program from the region's fish and wildlife agencies and Indian tribes. All measures adopted by the Council were also required to be consistent with the management objectives of the agencies and tribes [Section 4.(h)(6)(A)], the legal rights of Indian tribes in the region [Section 4.(h)(6)(D)] and be based upon and supported by the best available scientific knowledge [Section 4.(h)(6)(B)]. The Resident Fish Stock Status above Chief Joseph and Grand Coulee Dams Project, also known as the Joint Stock Assessment Project (JSAP) specifically addresses NPPC Council measure 10.8B.26 of the 1994 program. The Joint Stock Assessment Project is a management tool using ecosystem principles to manage artificial fish assemblages and native fish in altered environments existing in the Columbia River System above Chief Joseph and Grand Coulee Dams (Blocked Area). A three-phase approach of this project will enhance the fisheries resources of the Blocked Area by identifying data gaps, filling data gaps with research, and implementing management recommendations based on research results. The Blocked Area fisheries information is housed in a central location, allowing managers to view the entire system while making decisions, rather than basing management decisions on isolated portions of the system. The JSAP is designed and guided jointly by fisheries managers in the Blocked Area and the Columbia Basin Blocked Area Management Plan (1998

  4. Resident Fish Stock above Chief Joseph and Grand Coulee Dams; 2003-2004 Annual Report.

    SciTech Connect

    Connor, Jason M.; McLellan, Jason G.; Butler, Chris

    2005-11-01

    In 1980, the United States Congress enacted the Northwest Power Planning and Conservation Act (PL 96-501, 1980), which established the Northwest Power and Conservation Council (NPCC), formerly the Northwest Power Planning Council. The NPCC was directed by Congress to develop a regional Power Plan and also the Columbia River Basin Fish and Wildlife Program (FWP) to restore or replace losses of fish caused by construction and operation of hydroelectric dams in the Columbia River Basin. In developing the FWP, Congress specifically directed NPCC to solicit recommendations for measures to be included in the Program from the region's fish and wildlife agencies and Indian tribes. All measures adopted by the Council were also required to be consistent with the management objectives of the agencies and tribes [Section 4.(h)(6)(A)], the legal rights of Indian tribes in the region [Section 4.(h)(6)(D)] and be based upon and supported by the best available scientific knowledge [Section 4.(h)(6)(B)]. The Resident Fish Stock Status above Chief Joseph and Grand Coulee Dams Project, also known as the Joint Stock Assessment Project (JSAP) specifically addresses NPPC Council measure 10.8B.26 of the 1994 program. The Joint Stock Assessment Project is a management tool using ecosystem principles to manage artificial and native fish assemblages in altered environments existing in the Columbia River System above Chief Joseph and Grand Coulee Dams (Blocked Area). A three-phase approach of this project will enhance the fisheries resources of the Blocked Area by identifying data gaps, filling data gaps with research, and implementing management recommendations based on research results. The Blocked Area fisheries information is housed in a central location, allowing managers to view the entire system while making decisions, rather than basing management decisions on isolated portions of the system. The JSAP is designed and guided jointly by fisheries managers in the Blocked Area. The

  5. Resident Fish Stock above Chief Joseph and Grand Coulee Dams; 2002 Annual Report.

    SciTech Connect

    Connor, Jason M.; McLellan, Jason G.; Butler, Chris

    2003-09-01

    In 1980, the United States Congress enacted the Northwest Power Planning and Conservation Act (PL 96-501, 1980), which established the Northwest Power and Conservation Council (NPCC), formerly the Northwest Power Planning Council. The NPCC was directed by Congress to develop a regional Power Plan and also the Columbia River Basin Fish and Wildlife Program (FWP) to restore or replace losses of fish caused by construction and operation of hydroelectric dams in the Columbia River Basin. In developing the FWP, Congress specifically directed NPCC to solicit recommendations for measures to be included in the Program from the region's fish and wildlife agencies and Indian tribes. All measures adopted by the Council were also required to be consistent with the management objectives of the agencies and tribes [Section 4.(h)(6)(A)], the legal rights of Indian tribes in the region [Section 4.(h)(6)(D)] and be based upon and supported by the best available scientific knowledge [Section 4.(h)(6)(B)]. The Resident Fish Stock Status above Chief Joseph and Grand Coulee Dams Project, also known as the Joint Stock Assessment Project (JSAP) specifically addresses NPPC Council measure 10.8B.26 of the 1994 program. The Joint Stock Assessment Project is a management tool using ecosystem principles to manage artificial fish assemblages and native fish in altered environments existing in the Columbia River System above Chief Joseph and Grand Coulee Dams (Blocked Area). A three-phase approach of this project will enhance the fisheries resources of the Blocked Area by identifying data gaps, filling data gaps with research, and implementing management recommendations based on research results. The Blocked Area fisheries information is housed in a central location, allowing managers to view the entire system while making decisions, rather than basing management decisions on isolated portions of the system. The JSAP is designed and guided jointly by fisheries managers in the Blocked Area. The

  6. Resident Fish Stock Status above Chief Joseph and Grand Coulee Dams; 2002-2003 Annual Report.

    SciTech Connect

    Connor, Jason M.; McLellan, Jason G.; Butler, Chris

    2006-02-01

    In 1980, the United States Congress enacted the Northwest Power Planning and Conservation Act (PL 96-501, 1980), which established the Northwest Power and Conservation Council (NPCC), formerly the Northwest Power Planning Council. The NPCC was directed by Congress to develop a regional Power Plan and also the Columbia River Basin Fish and Wildlife Program (FWP) to restore or replace losses of fish caused by construction and operation of hydroelectric dams in the Columbia River Basin. In developing the FWP, Congress specifically directed NPCC to solicit recommendations for measures to be included in the Program from the region's fish and wildlife agencies and Indian tribes. All measures adopted by the Council were also required to be consistent with the management objectives of the agencies and tribes [Section 4.(h)(6)(A)], the legal rights of Indian tribes in the region [Section 4.(h)(6)(D)] and be based upon and supported by the best available scientific knowledge [Section 4.(h)(6)(B)]. The Resident Fish Stock Status above Chief Joseph and Grand Coulee Dams Project, also known as the Joint Stock Assessment Project (JSAP) specifically addresses NPPC Council measure 10.8B.26 of the 1994 program. The Joint Stock Assessment Project is a management tool using ecosystem principles to manage artificial and native fish assemblages in altered environments existing in the Columbia River System above Chief Joseph and Grand Coulee Dams (Blocked Area). A three-phase approach of this project will enhance the fisheries resources of the Blocked Area by identifying data gaps, filling data gaps with research, and implementing management recommendations based on research results. The Blocked Area fisheries information is housed in a central location, allowing managers to view the entire system while making decisions, rather than basing management decisions on isolated portions of the system. The JSAP is designed and guided jointly by fisheries managers in the Blocked Area. The

  7. Ataxin-3 and its e3 partners: implications for machado-joseph disease.

    PubMed

    Durcan, Thomas M; Fon, Edward A

    2013-01-01

    Machado-Joseph disease (MJD) is the most common dominant inherited ataxia worldwide, caused by an unstable CAG trinucleotide expansion mutation within the SCA3 gene resulting in an expanded polyglutamine tract within the ataxin-3 protein. Ataxin-3 functions as a deubiquitinating enzyme (DUB), within the Ub system and whilst many DUBs are known to partner with and deubiquitinate specific E3-Ub ligases, ataxin-3 had no identified E3 partner until recent studies implicated parkin and CHIP, two neuroprotective E3 ligases. MJD often presents with symptoms of Parkinson disease (PD), which led to identification of parkin as a novel E3-Ub ligase whose activity was regulated by ataxin-3-mediated deubiquitination. Findings from these studies also revealed an unexpected convergence upon the E2-Ub-conjugating enzyme in the regulation of an E3/DUBenzyme pair. Moreover, mutant but not wild-type ataxin-3 promotes the clearance of parkin via the autophagy pathway, raising the intriguing possibility that increased turnover of parkin may contribute to the pathogenesis of MJD and help explain some of the Parkinsonian features in MJD. In addition to parkin, the U-box E3 ligase CHIP, a neuroprotective E3 implicated in protein quality control, was identified as a second E3 partner of ataxin-3, with ataxin-3 regulating the ability of CHIP to ubiquitinate itself. Indeed, ataxin-3 not only deubiquitinated CHIP, but also trimmed Ub conjugates on CHIP substrates, thereby regulating the length of Ub chains. Interestingly, when expanded ataxin-3 was present, CHIP levels were also reduced in the brains of MJD transgenic mice, raising the possibility that loss of one or both E3 partners may be a contributing factor in the pathogenesis of SCA3. In this review we discuss the implications from these studies and describe the importance of these findings in helping us understand the molecular processes involved in SCA3 and other neurodegenerative disorders. PMID:23653622

  8. Sir Joseph Barcroft, Cambridge placental and fetal research (1933-1966) and inter-generational Science.

    PubMed

    Boyd, Robert; Boyd, C A Richard

    2010-01-01

    The nature of Cambridge (UK) placental and fetal research in the middle third of the twentieth century is reviewed on the basis of published literature and personal recollection. Joseph Barcroft is a central figure who came to fetal research late in an extremely productive career which is briefly sketched. Contemporaneous Cambridge academics in the field included J.D. Boyd (the authors father), J. Hammond, F.H.A. Marshall, R.A. McCance, J. Needham, A.S. Parkes and Elsie Widdowson. The then current Cambridge academic geography is explained and features of its scientific life such as funding, institutional structure and ethos, teaching and clinical duties, domestic and gender roles, and political context, including war and empire, are briefly considered. The testing of research findings against general principles and use of quantitative thinking are identified as important features. Intergenerational connections, often within individual families, are identified as a striking feature. The long-term impact of Cambridge work of this period; locally, in current trophoblast and feto-placental genetic research, in Oxford in probably influencing G.S. Dawes research leadership, and internationally, especially through D.H. Barron, and through him to the Denver School, is considered. That human placental and embryological specimens collected by J.D. Boyd have received a new lease of life as the "Boyd Collection", including use by Allen Enders is noted. Mechanisms for the maintenance of scientific quality and productivity during the period, mainly through the scientist himself relying on an internalised sense of "obligation", are contrasted with those current in the UK and more widely; formal peer-review at frequent intervals, with subsequent allocation of short-term funding. The strengths and weaknesses of each are considered. PMID:19876838

  9. Spinocerebellar ataxia type 3/Machado-Joseph disease starting before adolescence.

    PubMed

    Donis, Karina Carvalho; Saute, Jonas Alex Morales; Krum-Santos, Ana Carolina; Furtado, Gabriel Vasata; Mattos, Eduardo Preusser; Saraiva-Pereira, Maria Luiza; Torman, Vanessa Leotti; Jardim, Laura Bannach

    2016-04-01

    Onset of Machado-Joseph disease (SCA3/MJD) before adolescence has been rarely reported. This study aims to describe a cohort of SCA3/MJD with onset before 12 years of age, comparing their disease progression with the progression observed in patients with usual disease onset. We identified all cases from our cohort whose onset was before adolescence. After consent, patients were examined with clinical scales Scale for the Assessment and Rating of Ataxia (SARA) and Neurological Examination Score for Spinocerebellar Ataxia (NESSCA). Gender, age, age at onset, disease duration, CAG expanded repeats, transmitting parent, and anticipation of cases with infantile and adult onset were studied. Progression of NESSCA and SARA scores was estimated through a mixed model, and was compared with a historical group with onset after adolescence. Between 2000 and 2014, 461 symptomatic individuals from our region were diagnosed as SCA3/MJD. Onset of eight cases (2.2 %), all heterozygotes, was before adolescence: seven were females (p = 0.054). CAG expanded repeats-75 ± 3 versus 84 ± 4-and anticipations-7 ± 9.7 versus 14.4 ± 7.2 years-were different between early childhood and adult onset groups (p < 0.03). The median survival of early childhood onset group was 23 years of age. The annual progression of SARA-2.3 and 0.6 points/year (p = 0.001)-and NESSCA-2.04 and 0.88 points/year (p = 0.043)-was faster in childhood than in adult onset group. Onset of SCA3/MJD before adolescence was related to larger expanded CAG repeats in heterozygosis; females seemed to be at higher risk. Disease progression was faster than in SCA3/MJD starting after 12 years. PMID:26780339

  10. Genetic counseling and presymptomatic testing programs for Machado-Joseph Disease: lessons from Brazil and Portugal

    PubMed Central

    Schuler-Faccini, Lavínia; Osorio, Claudio Maria; Romariz, Flavia; Paneque, Milena; Sequeiros, Jorge; Jardim, Laura Bannach

    2014-01-01

    Machado-Joseph disease (MJD) is an autosomal dominant, late-onset neurological disorder and the most common form of spinocerebellar ataxia (SCA) worldwide. Diagnostic genetic testing is available to detect the disease-causing mutation by direct sizing of the CAG repeat tract in the ataxin 3 gene. Presymptomatic testing (PST) can be used to identify persons at risk of developing the disease. Genetic counseling provides patients with information about the disease, genetic risks, PST, and the decision-making process. In this study, we present the protocol used in PST for MJD and the relevant observations from two centers: Brazil (Porto Alegre) and Portugal (Porto). We provide a case report that illustrates the significant ethical and psychological issues related to PST in late-onset neurological disorders. In both centers, counseling and PST are performed by a multidisciplinary team, and genetic testing is conducted at the same institutions. From 1999 to 2012, 343 individuals sought PST in Porto Alegre; 263 (77%) of these individuals were from families with MJD. In Porto, 1,530 individuals sought PST between 1996 and 2013, but only 66 (4%) individuals were from families with MJD. In Brazil, approximately 50% of the people seeking PST eventually took the test and received their results, whereas 77% took the test in Portugal. In this case report, we highlight several issues that might be raised by the consultand and how the team can extract significant information. Literature about PST testing for MJD and other SCAs is scarce, and we hope this report will encourage similar studies and enable the implementation of PST protocols in other populations, mainly in Latin America. PMID:24764760

  11. Cognitive and olfactory deficits in Machado-Joseph disease: a dopamine transporter study.

    PubMed

    Braga-Neto, Pedro; Felicio, Andre C; Hoexter, Marcelo Q; Pedroso, José Luiz; Dutra, Lívia Almeida; Alessi, Helena; Minett, Thaís; Santos-Galduroz, Ruth F; da Rocha, Antônio José; Garcia, Lucas A L; Bertolucci, Paulo Henrique F; Bressan, Rodrigo A; Barsottini, Orlando Graziani Povoas

    2012-08-01

    Cognitive and olfactory impairments have been demonstrated in patients with Machado-Joseph disease (MJD), and a possible relationship with dopaminergic dysfunction is implicated. However, there is still controversy regarding the pattern of striatal dopaminergic dysfunction in patients with MJD. In this study, we investigated whether these patients had different dopamine transporter (DAT) densities as compared to healthy subjects, and correlated these data with cognitive performance and sense of smell. Twenty-two MJD patients and 20 control subjects were enrolled. The neuropsychological assessment comprised the spatial span, symbol search, picture completion, stroop color word test, trail making test and phonemic verbal fluency test. The 16-item Sniffin' Sticks was used to evaluate odor identification. DAT imaging was performed using the SPECT radioligand [(99m)Tc]-TRODAT-1, alongside with Magnetic Resonance imaging. Patients with MJD showed significantly lower DAT density in the caudate (1.34 ± 0.27 versus 2.02 ± 0.50, p < 0.001), posterior putamen (0.81 ± 0.32 versus 1.32 ± 0.34, p < 0.001) and anterior putamen (1.10 ± 0.31 versus 1.85 ± 0.45, p < 0.001) compared with healthy controls. The putamen/caudate ratio was also significantly lower in patients compared with controls (0.73 ± 0.038 versus 0.85 ± 0.032, p = 0.027). Even though we had only two patients with parkinsonism, we detected striatal dopaminergic deficits in those patients. No significant correlations were detected between DAT density and cognitive performance or Sniffin' Sticks scores. The data suggests that striatal dopamine deficit is not involved in cognitive or sense of smell deficits. This finding raises the possibility of extra-striatal dopamine and other neurotransmitter system involvement or of cerebellum neurodegeneration exerting a direct influence on cognitive and sensorial information processing in MJD. PMID:22575233

  12. A linkage study of Machado-Joseph disease - refining the localisation of the gene

    SciTech Connect

    Gaspar, C.; Twist, E.C.; Maciel, P.

    1994-09-01

    Machado-Joseph disease (MJD) is an autosomal dominant neurodegenerative ataxia originally described in families of Azorean-Portuguese descent. It is believed to be due to the mutation of a single, as yet unidentified gene which has been mapped using genetic linkage analysis to a 29 cM region of chromosome 14q24.3-q32 in five Japanese families. The aim of this study was to refine the localization of the MJD gene by typing additional markers in this 29 cM interval. Blood was collected and DNA isolated from 355 individuals including 171 affected persons who are part of 6 Portuguese/Azorean, 6 American/Azorean and 1 Brazilian kindred. Pedigrees were typed with highly polymorphic di- and tetranucleotide repeat markers spanning the 29 cM region of chromosome 14q containing the gene. Markers tested include D14S74, D14S55, D14S124, D14S48, D14S128, D14S68, D14S256, AFM343vfl, D14S45, and D14S51. Linkage between the MJD locus and the markers was analyzed using the computer programs LIPED and LINKAGE. In addition, haplotype analysis of all 13 families was carried out. To date, the maximum cumulative two point lod score of 14.34 at a recombination fraction of 0.05 has been obtained with the marker AFM343vfl. From haplotype analysis, D14S68 and AFM343vfl have been identified as flanking markers. Thus the region of chromosome 14q containing the MJD gene has been narrowed from an interval of 29 cm to approximately 11 cM.

  13. Chief Joseph Kokanee Enhancement Project : Confederated Tribes of the Colville Reservaton 1997 Annual Report.

    SciTech Connect

    LeCaire, Richard

    1998-01-01

    In the early 1980's the Confederated Tribes of the Colville Reservation, the Spokane Tribe of Indians and the Washington Dept. of Fish and Wildlife developed a management plan for Lake Roosevelt on the restoration and enhancement of kokanee salmon populations using hatchery out plants and the restoration of natural spawning runs. The plan was incorporated into the Northwest Power Planning Council (NPPC) in their 1987 Columbia Basin Fish and Wildlife program as partial mitigation for hydropower caused fish losses resulting from the construction of Grand Coulee Dam. The Chief Joseph Kokanee Enhancement Project, as part of a basin wide effort, is evaluating the status of the natural production kokanee in streams tributary to Lakes Roosevelt and Rufus Woods and is examining entrainment through Grand Coulee Dam. The goal of this project is the protection and enhancement of the natural production kokanee in these two lakes. The project is currently collecting data under four phases or parts. Since 1991, Lake Whatcom Washington origin kokanee have been planted in considerable numbers into the waters of Lake Roosevelt. A natural production kokanee fishery has persisted in the lake since the early 1970's(Cash, 1995), (Scholz, 1991). Historical information alludes to wild Kokanee production in the San Poil River, Nespelem River, Big Sheep Creek, Ora-Pa-Ken Creek, Deep Creek and Onion Creeks. The genetic makeup of the fish within the fishery is unknown, as is their contribution to the fishery. The level of influence by the hatchery out planted stock on wild fish stocks is unknown as well. Project outcomes will indicate the genetic fitness for inclusion of natural production kokanee stocks into current Bonneville Power Administration funded hatchery programs. Other findings may determine contribution/interaction of/between wild/hatchery kokanee stocks found in the waters of Lake Franklin D. Roosevelt.

  14. Ataxin-3 and Its E3 Partners: Implications for Machado–Joseph Disease

    PubMed Central

    Durcan, Thomas M.; Fon, Edward A.

    2013-01-01

    Machado–Joseph disease (MJD) is the most common dominant inherited ataxia worldwide, caused by an unstable CAG trinucleotide expansion mutation within the SCA3 gene resulting in an expanded polyglutamine tract within the ataxin-3 protein. Ataxin-3 functions as a deubiquitinating enzyme (DUB), within the Ub system and whilst many DUBs are known to partner with and deubiquitinate specific E3-Ub ligases, ataxin-3 had no identified E3 partner until recent studies implicated parkin and CHIP, two neuroprotective E3 ligases. MJD often presents with symptoms of Parkinson disease (PD), which led to identification of parkin as a novel E3-Ub ligase whose activity was regulated by ataxin-3-mediated deubiquitination. Findings from these studies also revealed an unexpected convergence upon the E2-Ub-conjugating enzyme in the regulation of an E3/DUBenzyme pair. Moreover, mutant but not wild-type ataxin-3 promotes the clearance of parkin via the autophagy pathway, raising the intriguing possibility that increased turnover of parkin may contribute to the pathogenesis of MJD and help explain some of the Parkinsonian features in MJD. In addition to parkin, the U-box E3 ligase CHIP, a neuroprotective E3 implicated in protein quality control, was identified as a second E3 partner of ataxin-3, with ataxin-3 regulating the ability of CHIP to ubiquitinate itself. Indeed, ataxin-3 not only deubiquitinated CHIP, but also trimmed Ub conjugates on CHIP substrates, thereby regulating the length of Ub chains. Interestingly, when expanded ataxin-3 was present, CHIP levels were also reduced in the brains of MJD transgenic mice, raising the possibility that loss of one or both E3 partners may be a contributing factor in the pathogenesis of SCA3. In this review we discuss the implications from these studies and describe the importance of these findings in helping us understand the molecular processes involved in SCA3 and other neurodegenerative disorders. PMID:23653622

  15. [Carcinoma of Unknown Primary Associated with a Sister Mary Joseph's Nodule--A Case Report].

    PubMed

    Yabe, Nobushige; Murai, Shinji; Yokose, Takahiro; Oto, Ippei; Yoshikawa, Takahisa; Kitasato, Kenjiro; Shimizu, Hirotomo; Kojima, Kenji; Hasegawa, Hirotoshi; Kitagawa, Yuko

    2015-11-01

    A 72-year old woman visited our hospital complaining of an umbilical mass and a foul smell from the umbilical region. During the evaluation, a massive immobile tumor was palpated in the center of the lower abdomen in addition to an umbilical mass with necrosis. Computed tomography (CT) revealed a massive ovarian tumor accompanied by an umbilical tumor and cyst with peritoneal dissemination, metastases in the liver and spleen and a urachal tumor. There were no symptoms or imaging findings of gastrointestinal obstruction. While searching for the primary focus, it was determined that the ovarian tumor was not of ovarian origin. Under these circumstances, colonoscopy was the only remaining diagnostic modality. However, evaluation of the large intestine was impossible due to compression by the tumor, and diverticulosis of the sigmoid colon did not allow smooth insertion of the colonoscope. Therefore, an excisional biopsy of the umbilical tumor was performed. The most likely diagnoses based on the histopathological findings were colorectal cancer and urachal cancer. Therefore , mFOLFOX6 was selected for chemotherapy because it has been reported to be effective against both urachal and colorectal cancer. At the time of writing, good tumor control had been achieved in the lesions evaluated. Cases of Sister Mary Joseph's nodule have sporadically been reported. The most common primary foci for peritoneal metastases are the stomach, pancreas and ovary. However, in the present case, these sites were ruled out and the primary focus remained unidentified, making it difficult to select appropriate treatment. We present this case with a discussion of the literature. PMID:26805190

  16. Hydrologic and water-quality characteristics of a Wetland receiving wastewater effluent in St. Joseph, Minnesota

    USGS Publications Warehouse

    Brown, Rob G.; Stark, James R.

    1989-01-01

    Hydrologic and water-quality characteristics were determined for a wetland being used for tertiary treatment of wastewater in St. Joseph, Minnesota. The wetland consists of spruce-tamarack fen and a cattail marsh, with the wastewater being discharged into the fen, and the fen draining into the marsh. The wetland is underlain by flat-lying glacial outwash that ranges from 0 to greater than 20 m in thickness. Horizontal ground-water movement in the outwash aquifer is toward the wetland from the south, east, and west. There is a strong upward vertical hydraulic gradient (about 0.1) in the ground-water flow system beneath and around the wetland. Regionally, the glacial-outwash aquifer is unconfined, but it is confined or partly confined locally by peat deposits under the wetland. Analysis of the hydrologic balance of the fen from October 1985 through September 1986 indicates that the inflow was 44 percent ground water, 38 percent wastewater, 11 percent runoff (storm sewer), and 7 percent precipitation. The fen outflow was 93 percent surface water and 7 percent evapotranspiration. Inflow to the marsh was 74 percent surface water, 21 percent ground water, and 5 percent precipitation. Outflow from the marsh was 94 percent surface water and 6 percent evapotranspiration. Wastewater contributed 74,996, and 81 percent of the total suspended solids, total phosphorus, and total ammonia plus organic nitrogen in the fen, respectively. Other chemical inputs were from the storm sewer, ground water, and atmospheric deposition. The fen was found to retain 34, 14, and 14 percent of the suspended solids, total phosphorus, and total ammonia plus organic nitrogen, respectively. The marsh retained 44, 18, and 22 percent of these three constituents, respectively.

  17. Silencing Mutant Ataxin-3 Rescues Motor Deficits and Neuropathology in Machado-Joseph Disease Transgenic Mice

    PubMed Central

    Onofre, Isabel; Albuquerque, David; Hirai, Hirokazu; Déglon, Nicole; de Almeida, Luís Pereira

    2013-01-01

    Machado-Joseph disease (MJD) or spinocerebellar ataxia type 3 (SCA3) is an autosomal dominantly-inherited neurodegenerative disorder caused by the over-repetition of a CAG codon in the MJD1 gene. This expansion translates into a polyglutamine tract that confers a toxic gain-of-function to the mutant protein – ataxin-3, leading to neurodegeneration in specific brain regions, with particular severity in the cerebellum. No treatment able to modify the disease progression is available. However, gene silencing by RNA interference has shown promising results. Therefore, in this study we investigated whether lentiviral-mediated allele-specific silencing of the mutant ataxin-3 gene, after disease onset, would rescue the motor behavior deficits and neuropathological features in a severely impaired transgenic mouse model of MJD. For this purpose, we injected lentiviral vectors encoding allele-specific silencing-sequences (shAtx3) into the cerebellum of diseased transgenic mice expressing the targeted C-variant of mutant ataxin-3 present in 70% of MJD patients. This variation permits to discriminate between the wild-type and mutant forms, maintaining the normal function of the wild-type allele and silencing only the mutant form. Quantitative analysis of rotarod performance, footprint and activity patterns revealed significant and robust alleviation of gait, balance (average 3-fold increase of rotarod test time), locomotor and exploratory activity impairments in shAtx3-injected mice, as compared to control ones injected with shGFP. An important improvement of neuropathology was also observed, regarding the number of intranuclear inclusions, calbindin and DARPP-32 immunoreactivity, fluorojade B and Golgi staining and molecular and granular layers thickness. These data demonstrate for the first time the efficacy of gene silencing in blocking the MJD-associated motor-behavior and neuropathological abnormalities after the onset of the disease, supporting the use of this strategy

  18. From Dodge City to Emerald City: The Importance of Joseph E. Zins' Work in Teacher Education Programs--A Commentary on "The Scientific Base Linking Social and Emotional Learning to School Success," a Chapter by Joseph E. Zins, Michelle R. Bloodworth, Roger P. Weissberg, and Herbert J. Walberg

    ERIC Educational Resources Information Center

    Carlson, David Lee

    2007-01-01

    This commentary argues that Joseph Zins' work can contribute and enhance university-based teacher preparation programs. Focusing on secondary English Education, it examines how SEL competencies can improve the curricula and field experiences to support pre-service teachers.

  19. Surgical pathology in the era of the Civil War: the remarkable life and accomplishments of Joseph Janvier Woodward, MD.

    PubMed

    Rapkiewicz, Amy V; Hawk, Alan; Noe, Adrienne; Berman, David M

    2005-10-01

    Joseph Janvier Woodward was an assistant surgeon in the US Army during the Civil War, coauthored the definitive works on the mortality and morbidity of that war, attended at the autopsy of President Lincoln, and attended President Garfield after he was shot. He revolutionized the field of photomicroscopy and was one of the first pathologists to use aniline dyes as tissue stains. Yet despite the occasional biographical sketch every few decades, he is largely unknown today. Herein, we review his contributions to surgical pathology and medicine and present modern-day photomicrographs of 140-year-old slides from Woodward's original collection. PMID:16196522

  20. Franz Joseph Gall on greatness in the fine arts: A collaboration of multiple cortical faculties of mind.

    PubMed

    Eling, Paul; Finger, Stanley

    2015-10-01

    Although Franz Joseph Gall (1758-1828) is well known for his organology, i.e., his theory of cortical localization of function largely derived from skull features, little has been written about his ideas pertaining to specific faculties other than speech, and even less attention has been drawn to how the individual faculties might work together in specific situations. Our focus shall be on how Franz Joseph Gall viewed the fine arts, with special emphasis on what one must possess to be outstanding in this field, which he associated with perceiving and understanding relationships, and several higher faculties of mind, including color, "constructiveness," locality, and recognizing people. How these faculties are utilized, he tells us, will vary with whether an artist does portraits, landscapes, historical scenes, still life compositions, etc., as well as with the selected medium (e.g., oil paints, sketching on paper, stones to be carved). To put Gall's thoughts about the fine arts in context, brief mention will be made of his scientific career, his guiding philosophy, the questions he most wanted to answer, what he construed as "evidence," how he eliminated the soul or "controller" from his system, and how he presented his work to the public. Some comparisons will be made to what he wrote about having a talent for music. PMID:26188788

  1. Telegram from Senator Joseph McCarthy to President Harry S. Truman. The Constitution Community: Postwar United States (1945 to Early 1970s).

    ERIC Educational Resources Information Center

    Gray, Tom

    As soon as World War II ended, the United States and the Soviet Union began a struggle for supremacy. It was against the backdrop of the Cold War that the threat of internal subversion and external attack began to preoccupy Congress. On February 9, 1950, Senator Joseph McCarthy gave a speech in Wheeling, West Virginia, where he claimed to have in…

  2. Being a Stranger and the Strangeness of Being: Joseph Conrad's "The Secret Sharer" as an Allegory of Being in Education

    ERIC Educational Resources Information Center

    Schwieler, Elias

    2013-01-01

    Joseph Conrad's "The Secret Sharer" has often been associated with what can be called initiation stories. However, in this article I argue that Conrad's text is more than that. It can, I suggest, be read as an allegory of the inaccessibility to reveal the essence of being in command, being in education, and also the…

  3. Changing the Script for Youth Development: An Evaluation of the All Stars Talent Show Network and the Joseph A. Forgione Development School for Youth.

    ERIC Educational Resources Information Center

    Gordon, Edmund W.; Bowman, Carol Bonilla; Mejia, Brenda X.

    This evaluation describes two supplementary education interventions: the All Stars Talent Show Network (ASTSN) and the Joseph A. Forgione Development School for Youth (DSY). The ASTSN is a 19-year-old program that provides youth age 5-25 with opportunities to produce and participate in talent shows, thus creating stages where youth can…

  4. 33 CFR 334.670 - Gulf of Mexico south and west of Apalachicola, San Blas, and St. Joseph bays; air-to-air firing...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Gulf of Mexico south and west of Apalachicola, San Blas, and St. Joseph bays; air-to-air firing practice range, Tyndall Air Force Base, Fla. 334..., DEPARTMENT OF DEFENSE DANGER ZONE AND RESTRICTED AREA REGULATIONS § 334.670 Gulf of Mexico south and west...

  5. The Chicago Board of Education Desegregation Policies and Practices [1975-1985]: A Historical Examination of the Administrations of Superintendents Dr. Joseph P. Hannon and Dr. Ruth Love

    ERIC Educational Resources Information Center

    James, Michael

    2009-01-01

    The purpose of this study will be to examine the policies and practices of two distinguished superintendents of the Chicago Public Schools: Dr. Joseph P. Hannon and the first African American female Superintendent Dr. Ruth Love. Hannon's four year administration extended from 1975 through 1979. Love's administration encompassed the years 1980…

  6. Designing a Core Curriculum. Proceedings of an Institute on Core Curriculum Design at Saint Joseph's College, Rensselaer, Indiana, June 3-8, 1979.

    ERIC Educational Resources Information Center

    Nichols, John P., Ed.; Groppe, John D., Ed.

    A report of the proceedings of an Institute on Core Curriculum Design, held in June, 1979 at Saint Joseph's College, Rensselaer, Indiana, is presented. Contents include: prefatory matter including the director's preface, the editor's preface, a list of participants, the schedule of the activities of the institute, the keynote address ("On Getting…

  7. Joseph Priestley across Theology, Education, and Chemistry: An Interdisciplinary Case Study in Epistemology with a Focus on the Science Education Context

    ERIC Educational Resources Information Center

    de Berg, Kevin C.

    2011-01-01

    This paper discusses the findings of a search for the intellectual tools used by Joseph Priestley (1733-1804) in his chemistry, education, and theology documents. Priestley's enquiring democratic view of knowledge was applicable in all three areas and constitutes a significant part of his lifework. Current epistemological issues in science…

  8. 33 CFR 334.670 - Gulf of Mexico south and west of Apalachicola, San Blas, and St. Joseph bays; air-to-air firing...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Gulf of Mexico south and west of Apalachicola, San Blas, and St. Joseph bays; air-to-air firing practice range, Tyndall Air Force Base, Fla. 334..., DEPARTMENT OF DEFENSE DANGER ZONE AND RESTRICTED AREA REGULATIONS § 334.670 Gulf of Mexico south and west...

  9. Baron von Zach's business relations with the Munich entrepreneur Joseph von Utzschneider (German Title: Geschäftsbeziehungen des Barons von Zach zu dem Münchner Unternehmer Joseph von Utzschneider)

    NASA Astrophysics Data System (ADS)

    Schneider, Ivo

    The relationship between the astronomer von Zach on the one side and the entrepreneur Joseph von Utzschneider and his partner Georg von Reichenbach on the other dates presumably from the year 1807 when Zach spent two months in Munich. Already in the same year Zach had ordered an instrument for himself and began to solicit business for the institute of Reichenbach, Utzschneider, and Liebherr, which was founded in 1804. One of the clients canvassed by Zach was the director of the observatory in Naples Zuccari. Zuccari had ordered the whole equipment for the new observatory from this institute in 1813. The instruments for Naples, which were completed in 1814, were sent accompanied by Reichenbach by land and sea to their destination where Reichenbach supervised their setup. At that time Reichenbach had separated from Utzschneider who kept the optical institute in Benediktbeuern with his new partner Joseph von Fraunhofer whereas Reichenbach became owner of the mathematical-mechanical institute in Munich. For personal and economical reasons Utzschneider began soon after to produce not only optical glass but also optical devices similar to those offered by Reichenbach. As soon as two institutes in Munich competed against each other on the market for sophisticated geodetical and astronomical instruments Zach sided with Utzschneider. Zach's main professional argument for this decision was that both competitors got the optical glass for their instruments from Utzschneider's optical institute in Benediktbeuern. This meant that Utzschneider had first choice and so the optical part of his instruments could be considered as better than that of Reichenbach`s instruments. Zach's role as an agent in Italy and France for the sale of products coming from Utzschneider's manufactories is highlighted by three of Zach's letters to Utzschneider from 1817 and 1818, two of which are reproduced here for the first time.

  10. Beyond antisepsis: Examining the relevance of the works of Joseph Baron Lister to the contemporary surgeon-scientist

    PubMed Central

    Glass, Graeme E.

    2014-01-01

    As the father of antispesis, the legacy of Joseph Baron Lister is assured and his influence on the development of contemporary surgical practice is recognised in the context of his achievement of predictable, infection-free surgery. However, looking beyond Lister's finest achievement and examining this work in the context of his whole career as a surgeon-scientist reveals important lessons pertinent to aspiring peers in how, by replacing surgical dogma with observation, deductive reasoning and scientific verification, by pursuing good ideas in the face of resistance and by making research directly relevant and patient-focused, lasting changes can be accomplished. This short paper aims to put Lister's developments in antisepsis in the context of his whole career, to evaluate his legacy and to commend his approach to contemporary surgeon-scientists. PMID:25593429

  11. Caloric restriction blocks neuropathology and motor deficits in Machado–Joseph disease mouse models through SIRT1 pathway

    PubMed Central

    Cunha-Santos, Janete; Duarte-Neves, Joana; Carmona, Vitor; Guarente, Leonard; Pereira de Almeida, Luís; Cavadas, Cláudia

    2016-01-01

    Machado–Joseph disease (MJD) is a neurodegenerative disorder characterized by an abnormal expansion of the CAG triplet in the ATXN3 gene, translating into a polyglutamine tract within the ataxin-3 protein. The available treatments only ameliorate symptomatology and do not block disease progression. In this study we find that caloric restriction dramatically rescues the motor incoordination, imbalance and the associated neuropathology in transgenic MJD mice. We further show that caloric restriction rescues SIRT1 levels in transgenic MJD mice, whereas silencing SIRT1 is sufficient to prevent the beneficial effects on MJD pathology. In addition, the re-establishment of SIRT1 levels in MJD mouse model, through the gene delivery approach, significantly ameliorates neuropathology, reducing neuroinflammation and activating autophagy. Furthermore, the pharmacological activation of SIRT1 with resveratrol significantly reduces motor incoordination of MJD mice. The pharmacological SIRT1 activation could provide important benefits to treat MJD patients. PMID:27165717

  12. Beyond antisepsis: Examining the relevance of the works of Joseph Baron Lister to the contemporary surgeon-scientist.

    PubMed

    Glass, Graeme E

    2014-01-01

    As the father of antispesis, the legacy of Joseph Baron Lister is assured and his influence on the development of contemporary surgical practice is recognised in the context of his achievement of predictable, infection-free surgery. However, looking beyond Lister's finest achievement and examining this work in the context of his whole career as a surgeon-scientist reveals important lessons pertinent to aspiring peers in how, by replacing surgical dogma with observation, deductive reasoning and scientific verification, by pursuing good ideas in the face of resistance and by making research directly relevant and patient-focused, lasting changes can be accomplished. This short paper aims to put Lister's developments in antisepsis in the context of his whole career, to evaluate his legacy and to commend his approach to contemporary surgeon-scientists. PMID:25593429

  13. 'God grant it may do good two all': the madhouse practice of Joseph Mason, 1738-79.

    PubMed

    Smith, Leonard

    2016-06-01

    Private madhouses made a significant contribution to the development of psychiatric practices in eighteenth-century England. Joseph Mason of Bristol, proprietor of a madhouse at Stapleton and then at nearby Fishponds, was part of a dynasty of successful and respected mad-doctors. A deeply religious man, his Christian ethics constituted the guiding force in his work with patients and interactions with their relatives. He was also an astute man of business, who recognized that comfortable domestic surroundings and the achievement of recoveries would enhance his reputation and attract lucrative middle-class custom. His treatment approaches, illustrated in a 1763 diary, were eclectic and pragmatic, comprising various medicines, dietary regulation, graded social interactions, and the cultivation of individualized therapeutic relationships with his patients. PMID:26837815

  14. Eduard Hitzig's experiences in the Franco-Prussian War (1870-1871): the case of Joseph Masseau.

    PubMed

    Koehler, Peter J

    2012-07-01

    It is well known that Fritsch and Hitzig published the results of their experiments on cortical stimulation in 1870, the year in which the Franco-Prussian War (FPW) broke out. Several tall stories are found about Hitzig's role in the FPW; stories that have not been well documented. During this war, he worked at the military hospital in Nancy, where he was allowed to admit to his ward soldiers with head wounds. He made a close observation of the 20-year-old French soldier Joseph Masseau, who suffered from a right-sided cerebral abscess following a gunshot wound sustained during the Loire campaign on December 10, 1870 and was looked after in the military hospital of Nancy in January and February 1871. Hitzig related the clinical and autopsy observations to his recent experimental findings. A translation into English of part of the case report is provided. PMID:22724487

  15. Joseph Needham, CH, FRS, FBA., b. 9 December 1900; d. 24 April 1995. A Sailor's Tribute and a Memoir

    NASA Astrophysics Data System (ADS)

    Waters, D. W.

    Sailors, indeed anyone interested in the development of sailing craft, will be for ever indebted to Joseph Needham. Today they will find with ease literature that describes the origins, characteristics, and development of sailing craft in the various regions of the world; the inter-relationships between natural products, and native hull stuctures and forms, sails' fabrics, shapes, and performance. They can learn, too, that the closestowing anchor, the water-tight bulkhead, the balanced rudder (and other features of the modern efficiency-conscious ship constructor) have all been adapted from the millenniaold, so-long-despised by Westerners, Chinese junk, just as has, late in this twentieth century, the stiffened sail of the modern high-performance yacht.

  16. "If I only touch her cloak": the Sisters of Charity of St. Joseph in New Orleans hospital, 1834-1860.

    PubMed

    Kong, Hyejung Grace; Kim, Ock-Joo

    2015-04-01

    This study is about the Sisters of Charity of St. Joseph in New Orleans' Charity Hospital during the years between 1834 and 1860. The Sisters of Charity of St. Joseph was founded in 1809 by Saint Elizabeth Ann Bailey Seton (first native-born North American canonized in 1975) in Emmitsburg, Maryland. Seton's Sisters of Charity was the first community for religious women to be established in the United States and was later incorporated with the French Daughters of Charity of St. Vincent de Paul in 1850. A call to work in New Orleans' Charity Hospital in the 1830s meant a significant achievement for the Sisters of Charity, since it was the second oldest continuously operating public hospitals in the United States until 2005, bearing the same name over the decades. In 1834, Sister Regina Smith and other sisters were officially called to Charity Hospital, in order to supersede the existing "nurses, attendants, and servants," and take a complete charge of the internal management of Charity Hospital. The existing scholarship on the history of hospitals and Catholic nursing has not integrated the concrete stories of the Sisters of Charity into the broader histories of institutionalized medicine, gender, and religion. Along with a variety of primary sources, this study primarily relies on the Charity Hospital History Folder stored at the Daughters of Charity West Center Province Archives. Located in the "Queen city of the South," Charity Hospital was the center of the southern medical profession and the world's fair of people and diseases. Charity Hospital provided the sisters with a unique situation that religion and medicine became intertwined. The Sisters, as nurses, constructed a new atmosphere of caring for patients and even their families inside and outside the hospital, and built their own separate space within the hospital walls. As hospital managers, the Sisters of Charity were put in complete charge of the hospital, which was never seen in other hospitals. By

  17. Intravenous administration of brain-targeted stable nucleic acid lipid particles alleviates Machado-Joseph disease neurological phenotype.

    PubMed

    Conceição, Mariana; Mendonça, Liliana; Nóbrega, Clévio; Gomes, Célia; Costa, Pedro; Hirai, Hirokazu; Moreira, João Nuno; Lima, Maria C; Manjunath, N; Pereira de Almeida, Luís

    2016-03-01

    Others and we showed that RNA interference holds great promise for the treatment of dominantly inherited neurodegenerative disorders such as Machado-Joseph disease (MJD), for which there is no available treatment. However, successful experiments involved intracranial administration of viral vectors and there is a need for a safer and less invasive procedure. In this work, we successfully generated stable nucleic acid lipid particles (SNALPs), incorporating a short peptide derived from rabies virus glycoprotein (RVG-9r) and encapsulating small interfering RNAs (siRNAs), which can target mutant ataxin-3. The developed formulation exhibited important features that make it adequate for systemic administration: high encapsulation efficiency of siRNAs, ability to protect the encapsulated siRNAs, appropriate and homogeneous particle size distribution. Following optimization of the formulation and in vitro validation of its efficacy to silence the MJD-causing protein - mutant ataxin-3 - in neuronal cells, in vivo experiments showed that intravenous administration of RVG-9r-targeted SNALPs efficiently silenced mutant ataxin-3 reducing neuropathology and motor behavior deficits in two mouse models of MJD. To our knowledge, this is the first report showing beneficial impact of a non-viral gene silencing strategy in MJD and the first time that a non-invasive systemic administration proved to be beneficial on a polyglutamine disorder. Our study opens new avenues towards MJD therapy that can also be applied to other neurodegenerative diseases linked to the production of pathogenic proteins. PMID:26757259

  18. Spinocerebellar ataxia type 3/Machado-Joseph disease: segregation patterns and factors influencing instability of expanded CAG transmissions.

    PubMed

    Souza, G N; Kersting, N; Krum-Santos, A C; Santos, A S P; Furtado, G V; Pacheco, D; Gonçalves, T A; Saute, J A; Schuler-Faccini, L; Mattos, E P; Saraiva-Pereira, M L; Jardim, L B

    2016-08-01

    Controversies about Mendelian segregation and CAG expansion (CAGexp) instabilities during meiosis in spinocerebellar ataxia type 3/Machado-Joseph disease (SCA3/MJD) need clarification. Additional evidence about these issues was obtained from the cohort of all SCA3/MJD individuals living in South Brazil. A survey was carried out to update information registered since 2001. Deaths were checked with the Public Information System, and data was made anonymous. Anticipation and delta-CAGexp from parent-offspring pairs, and delta-CAGexp between siblings were obtained. One hundred and fifty-nine families (94% of the entire registry) were retrieved, comprising 3725 living individuals as of 2015, 625 of these being symptomatic. Minimal prevalence was 6:100,000. Carriers of a CAGexp represented 65.6% of sibs in the genotyped offspring (p < 0.001). Median instability was larger among paternal than maternal transmissions, and instabilities correlated with anticipation (r = 0.38; p = 0.001). Age of the parent correlated to delta-CAGexp among 115 direct parent-offspring CAGexp transmissions (ρ = 0.23, p = 0.014). In 98 additional kindreds, the delta-CAGexp between 269 siblings correlated with their delta-of-age (ρ = 0.27, p < 0.0001). SCA3/MJD was associated with a segregation distortion favoring the expanded allele in our cohort. Instability of expansion during meiosis was weakly influenced by the age of the transmitting parent at the time of conception. PMID:26693702

  19. [Photography as a resource of microscopic research? Joseph von Gerlach (1820-1896) and the early anatomical microphotographers].

    PubMed

    Stahnisch, Frank

    2005-06-01

    The Erlangen anatomist Joseph von Gerlach was one of the first medical researchers who used microphotography for their scientific aims in basic tissue research. Already in 1863, Gerlach published a famous handbook on the methodology of the microphotographic technique, entitled Die Photographie als Hülfsmittel mikroskopischer Forschung. Here, he discussed the technological, practical and epistemological standards and constraints of the newly introduced visualisation technique of scientific photography. The efforts and setbacks of Gerlachs' innovative approaches shall be characterised in the present paper. Furthermore, some of the most important arguments put forward by some of his peers are closely compared and thoroughly scrutinised. These anatomical and biological microscopists objected frequently to Gerlach's photographic approach as being "unscientific" or "insufficient" to support the growth of experimental morphology and neurohistological research. In his scientific self-defence, Gerlach developed important auxiliary arguments that display many facets of the epistemological discourse of 19th-century medical research, particularly on the question of how scientific objects should be visualised and identified in the experimental laboratory. PMID:16060071

  20. Joseph A. Burton Forum Award Talk: Remembering our Humanity: the deep impact of the Russell-Einstein Manifesto

    NASA Astrophysics Data System (ADS)

    Lewis, Patricia M.

    2009-05-01

    ``There lies before us, if we choose, continual progress in happiness, knowledge, and wisdom. Shall we, instead, choose death, because we cannot forget our quarrels? We appeal as human beings to human beings: Remember your humanity, and forget the rest.'' Days before his death, Albert Einstein joined Bertrand Russell and other notable scientists and philosophers in issuing a statement calling for the abolition of war and for governments to ``find peaceful means for the settlement of all matters of dispute between them." As a first step, they called for the renunciation of nuclear weapons. The initiative led to the establishment of the Pugwash Conferences on Science and World Affairs, which bring together influential scholars and public figures concerned with reducing the danger of armed conflict and seeking cooperative solutions for global problems. The Russell-Einstein Manifesto has had a major impact on the way in which people discuss the issues of peace and war. The paper traces the growing awareness of the meaning of war, ways in which violent conflict can be prevented, particularly in the nuclear age, and the humanitarian imperative for so doing. From the Russell-Einstein Manifesto, London, 9 July 1955, signed also by Max Born, Percy W. Bridgman, Leopold Infeld, Frederic Joliot-Curie, Herman J. Muller, Linus Pauling, Cecil F. Powell, Joseph Rotblat and Hideki Yukawa

  1. Integrating Strategic and Operational Decision Making Using Data-Driven Dashboards: The Case of St. Joseph Mercy Oakland Hospital.

    PubMed

    Jack Weiner; Balijepally, Venugopal; Tanniru, Mohan

    2015-01-01

    Hospitals have invested and continue to invest heavily in building information systems to support operations at various levels of administration. These systems generate a lot of data but fail to effectively convert these data into actionable information for decision makers. Such ineffectiveness often is attributed to a lack of alignment between strategic planning and information technology (IT) initiatives supporting operational goals. We present a case study that illustrates how the use of digital dashboards at St. Joseph Mercy Oakland (SJMO) Hospital in Pontiac, Michigan, was instrumental in supporting such an alignment. Driven by a focus on key performance indicators (KPIs), dashboard applications also led to other tangible and intangible benefits. An ability to track KPIs over time and against established targets, with drill-down capabilities, allowed leadership to hold staff members accountable for achieving their performance targets. By displaying the dashboards in prominent locations (such as operational unit floors, the physicians' cafeteria, and nursing stations), SJMO ushered in transparency in the planning and monitoring processes. The need to develop KPI metrics and drive data collection efforts became ingrained in the work ethos of people at every level of the organization. Although IT-enabled dashboards have been instrumental in supporting this cultural transformation, the focus of investment was the ability of technology to make collective vision and action the responsibility of all stakeholders. PMID:26554142

  2. Birth of scientific surgery. John Hunter versus Joseph Lister as the father or founder of scientific surgery.

    PubMed

    Toledo-Pereyra, Luis H

    2010-02-01

    John Hunter (1728-1793) has frequently been considered the "Father or Founder of Scientific Surgery". His inscription at Westminster Abbey presents him as "a gifted interpreter of the Divine Power and wisdom at work in the laws of organic life and the Founder of Scientific Surgery." I take issue with Hunter being considered the father or founder of scientific surgery and propose Joseph Lister (1827-1912) as the one who should receive this consideration. Hunter was a skilled surgeon, an inquisitive innovator, keen observer, great naturalist, and astute thinker, who made no surgical discoveries of any transcendence to the discipline. His scientific observations were not in the field of surgery. Therefore, he should not be considered the "Father or Founder of Scientific Surgery." On the contrary, Lister became a revolutionary scientific innovator by explaining the pervasive role of microorganisms in surgical wounds. His work directly affected surgery and its role in medicine. Lister, therefore, should be considered the "Father or Founder of Scientific Surgery." PMID:20232999

  3. Effects of agricultural irrigation on water resources in the St. Joseph River basin, Indiana, and implications for aquifer yield

    USGS Publications Warehouse

    Peters, J.G.; Renn, D.E.

    1988-01-01

    During the past decade, the acreage of irrigated agricultural land in Indiana has tripled, causing public concern about competition for water and resulting in several State laws for regulating water withdrawals. The St. Joseph River basin represents less than one-tenth of the area of the State, but it contains one-third of the State 's irrigated land. Irrigated land in the basin is composed of permeable soils that are underlain by productive glacial aquifers. A computer model was used to analyze the effects of maximum irrigation withdrawals on aquifer drawdown and streamflow in a 16.5 sq mi area of intensive irrigation. Simulation of maximum pumping resulted in predicted aquifer drawdowns of one-fourth of the total available drawdown. Flow in a nearby stream was decreased by 40%. Areas of most intensive irrigation in the basin also are areas that have productive aquifers and well-sustained streamflows. Aquifer yield is based on the concept of capture - the volume of increased recharge to the aquifer or decreased discharge from the aquifer that results from pumping. The high rates of capture for aquifers in the basin supply ample water for present (1982) irrigation and for substantial future development. (USGS)

  4. Selective occurrence of TDP-43-immunoreactive inclusions in the lower motor neurons in Machado-Joseph disease.

    PubMed

    Tan, Chun-Feng; Yamada, Mitsunori; Toyoshima, Yasuko; Yokoseki, Akio; Miki, Yukari; Hoshi, Yasuhiro; Kaneko, Hiroyuki; Ikeuchi, Takeshi; Onodera, Osamu; Kakita, Akiyoshi; Takahashi, Hitoshi

    2009-10-01

    Pathological transactivation-responsive DNA-binding protein 43 (TDP-43) has been identified as a component of ubiquitinated inclusions in frontotemporal lobar degeneration with motor neuron disease, as well as in sporadic and some forms of familial amyotrophic lateral sclerosis. To clarify whether pathological TDP-43 is present in other neurodegenerative diseases involving the motor neuron system, we immunohistochemically examined the brain and spinal cord affected by two CAG repeat (polyglutamine) diseases, Machado-Joseph disease (MJD) and spinal and bulbar muscular atrophy (SBMA), using polyclonal antibody against TDP-43. In all the MJD cases, TDP-43-immunoreactive (ir) neuronal cytoplasmic inclusions (NCIs), although few in number, were found only in the lower motor neurons in the brainstem and spinal cord. TDP-43-ir NCIs appeared as linear wisp-like, skein-like, or thick, somewhat rod-like bodies. These inclusions were also visualized with antibodies against phosphoserines 409 and 410 of TDP-43, and ubiquitin, but were not recognized by antibody against expanded polyglutamine stretches or ataxin-3. The ultrastructure of the TDP-43-ir NCIs was similar to that of the inclusions seen in sporadic ALS, consisting of bundles of parallel filaments. None of the SBMA cases showed abnormal TDP-43 immunoreactivity in any of the regions examined. Immunoblot analysis failed to recognize hyperphosphorylated TDP-43 at ~23 kDa in two MJD cases examined. However, the immunohistochemical findings strongly suggested that in MJD, in addition to the polyglutamine-dependent disease process, TDP-43-related pathogenesis is associated with degeneration and death of the lower motor neurons. PMID:19526244

  5. Psychosis in Machado-Joseph Disease: Clinical Correlates, Pathophysiological Discussion, and Functional Brain Imaging. Expanding the Cerebellar Cognitive Affective Syndrome.

    PubMed

    Braga-Neto, Pedro; Pedroso, José Luiz; Gadelha, Ary; Laureano, Maura Regina; de Souza Noto, Cristiano; Garrido, Griselda Jara; Barsottini, Orlando Graziani Povoas

    2016-08-01

    Machado-Joseph disease (MJD) is the most common spinocerebellar ataxia worldwide with a broad range of clinical manifestations, but psychotic symptoms were not previously characterized. We investigated the psychiatric manifestations of a large cohort of Brazilian patients with MJD in an attempt to characterize the presence of psychotic symptoms. We evaluated 112 patients with clinical and molecular diagnosis of MJD from February 2008 to November 2013. Patients with psychotic symptoms were referred to psychiatric evaluation and brain perfusion single-photon emission computed tomography (SPECT) analysis. A specific scale-Positive and Negative Syndrome Scale (PANSS)-was used to characterize psychotic symptoms in MJD patients. We also performed an autopsy from one of the patients with MJD and psychotic symptoms. Five patients presented psychotic symptoms. Patients with psychotic symptoms were older and had a late onset of the disease (p < 0.05). SPECT results showed that MJD patients had significant regional cerebral blood flow (rCBF) decrease in the cerebellum bilaterally and vermis compared with healthy subjects. No significant rCBF differences were found in patients without psychotic symptoms compared to patients with psychotic symptoms. The pathological description of a patient with MJD and psychotic symptoms revealed severe loss of neuron bodies in the dentate nucleus and substantia nigra. MJD patients with a late onset of the disease and older ones are at risk to develop psychotic symptoms during the disease progression. These clinical findings may be markers for an underlying cortical-cerebellar disconnection or degeneration of specific cortical and subcortical regions that may characterize the cerebellar cognitive affective syndrome. PMID:26298474

  6. Differential mtDNA damage patterns in a transgenic mouse model of Machado-Joseph disease (MJD/SCA3).

    PubMed

    Ramos, Amanda; Kazachkova, Nadiya; Silva, Francisca; Maciel, Patrícia; Silva-Fernandes, Anabela; Duarte-Silva, Sara; Santos, Cristina; Lima, Manuela

    2015-02-01

    Mitochondrial dysfunction has been associated with late onset neurodegenerative disorders, among which is Machado-Joseph disease (MJD/SCA3). In a previous study, using a transgenic mouse model of MJD, we reported a decrease in mitochondrial DNA (mtDNA) copy number and an accumulation of the 3876-bp deletion with age and with phenotype development. We extended this study by analyzing the pattern of mtDNA depletion and the accumulation of the 3876-bp deletion in 12 older transgenic (TG) and 4 wild-type (wt) animals, and by investigating the accumulation of somatic mutations in the D-loop region in 76 mice (42 TG and 34 wt). mtDNA damage was studied in TG and wt mice at different ages and tissues (blood, pontine nuclei, and hippocampus). Results for older mice demonstrate an accumulation of the mtDNA 3867-bp deletion with age, which was more pronounced in TG animals. Furthermore, the tendency for mtDNA copy number decrease with age, in all analyzed tissues of TG and wt animals, was also confirmed. No point mutations were detected in the D-loop, neither in TG nor wt animals, in any of the tissues analyzed. Due to the absence of mtDNA somatic mutations, we can suggest that mtDNA point mutation accumulation cannot be used to monitor the development and progression of the phenotype in this mouse model and likely in any MJD mice model. The present results further confirm not only the association between mtDNA alterations (copy number and deletions) and age, but also between such alterations and the expression of the mutant ataxin-3 in TG mice. PMID:25001003

  7. The quest for a better insight into physiology of fluids and barriers of the brain: the exemplary career of Joseph D. Fenstermacher.

    PubMed

    Chodobski, Adam; Ghersi-Egea, Jean-François; Nicholson, Charles; Nagaraja, Tavarekere N; Szmydynger-Chodobska, Joanna

    2015-01-01

    In June 2014 Dr. Joseph D. Fenstermacher celebrated his 80th birthday, which was honored by the symposium held in New London, NH, USA. This review discusses Fenstermacher's contribution to the field of fluids and barriers of the CNS. Specifically, his fundamental work on diffusion of molecules within the brain extracellular space and the research on properties of the blood-brain barrier in health and disease are described. Fenstermacher's early research on cerebrospinal fluid dynamics and the regulation of cerebral blood flow is also reviewed, followed by the discussion of his more recent work involving the use of magnetic resonance imaging. PMID:25745556

  8. [Pierre-Joseph Duhem (1758-1807), doctor regicide, and other National Convention physician-deputies vis-a-vis the lawsuit of Louis XVI].

    PubMed

    Dupont, Geneviève; Lellouch, Alain; Olry, Régis

    2006-01-01

    On January 16, 1793, seven hundred aud forty nine deputies of the National Convention are called on to express their opinion by word of mouth about this question: "What penalty Louis, former king of the French, brought upon himself ?" Among these deputies, 47 are or were physicians : 22 vote for death without delay, 3 for suspended death sentence, 20 for indulgence (imprisonment till the peace and banishment thereafter), and 2 refuse to vote. This paper aims at summarizing the attitude of the physicians-deputies, and more specifically those of Pierre-Joseph Duhem, at the time of one of the most famous trials of the history of France. PMID:17152600

  9. Machado-Joseph Disease

    MedlinePlus

    ... for drunkenness, difficulty with speech and swallowing, involuntary eye movements, double vision, and frequent urination. Some individuals also ... color and/or contrast, and inability to control eye movements. Is there any treatment? MJD is incurable, but ...

  10. Machado-Joseph Disease

    MedlinePlus

    ... for drunkenness, difficulty with speech and swallowing, impaired eye movements sometimes accompanied by double vision or bulging eyes, ... color and/or contrast, and inability to control eye movements. Some individuals also experience prominent Parkinson’s disease-like ...

  11. Chief Joseph Kokanee Enhancement Project; Strobe Light Deterrent Efficacy Test and Fish Behavior Determination at the Grand Coulee Dam Third Powerplant Forebay, 2002-2003 Annual Report.

    SciTech Connect

    Johnson, R.; McKinstry, C.; Simmons, C.

    2003-01-01

    Since 1995, the Confederated Tribes of the Colville Reservation (Colville Confederated Tribes) have managed the Chief Joseph Kokanee Enhancement Project as part of the Northwest Power Planning Council (NWPPC) Fish and Wildlife Program. Project objectives have focused on understanding natural production of kokanee (a land-locked sockeye salmon) and other fish stocks in the area above Grand Coulee and Chief Joseph Dams on the Columbia River. A 42-month investigation concluded that entrainment at Grand Coulee Dam ranged from 211,685 to 576,676 fish annually. Further analysis revealed that 85% of the total entrainment occurred at the dam's third powerplant. These numbers represent a significant loss to the tribal fisheries upstream of the dam. In response to a suggestion by the NWPPC Independent Scientific Review Panel, the scope of work for the Chief Joseph Kokanee Enhancement Project was expanded to include a multiyear pilot test of a strobe light system to help mitigate fish entrainment. This report details the work conducted during the second year of the study by researchers of the Colville Confederated Tribes in collaboration with the Pacific Northwest National Laboratory. The 2002 study period extended from May 18 through July 30. The objective of the study was to determine the efficacy of a prototype strobe light system to elicit a negative phototactic response in kokanee and rainbow trout. The prototype system consisted of six strobe lights affixed to an aluminum frame suspended vertically underwater from a barge secured in the center of the entrance to the third powerplant forebay. The lights, controlled by a computer, were aimed to illuminate a specific region directly upstream of the barge. Three light level treatments were used: 6 of 6 lights on, 3 of 6 lights on, and all lights off. These three treatment conditions were applied for an entire 24-hr day and were randomly assigned within a 3-day block throughout the study period. A seven-transducer splitbeam

  12. Chief Joseph Kokanee Enhancement Project; Strobe Light Deterrent Efficacy Test and Fish Behavior Determination at the Grand Coulee Dam Third Powerplant Forebay, 2004-2005 Annual Report.

    SciTech Connect

    Johnson, R.; McKinstry, C.; Cook, C.

    2005-02-01

    This report documents a four-year study(a) to assess the efficacy of a prototype strobe light system to elicit a negative phototactic response in kokanee (Oncorhynchus nerka kennerlyi) and rainbow trout (O. mykiss) at the entrance to the forebay of the third powerplant at Grand Coulee Dam. The work was conducted for the Bonneville Power Administration, U.S. Department of Energy, by Pacific Northwest National Laboratory (PNNL) in conjunction with the Confederated Tribes of the Colville Reservation (Colville Confederated Tribes). In this report, emphasis is placed on the methodology and results associated with the fourth project year and compared with findings from the previous years to provide an overall project summary. Since 1995, the Colville Confederated Tribes have managed the Chief Joseph Kokanee Enhancement Project as part of the Northwest Power and Conservation Council Fish and Wildlife Program. Project objectives have focused on understanding natural production of kokanee (a land-locked sockeye salmon) and other fish stocks in the area above Grand Coulee and Chief Joseph dams on the Columbia River (Figure S.1). A 42-month investigation from 1996 to 1999 determined that from 211,685 to 576,676 fish, including kokanee and rainbow trout, were entrained annually at Grand Coulee Dam. Analysis of the data found that 85% of the total entrainment occurred at the dam's third powerplant. Because these entrainment rates represent a significant loss to the tribal fisheries upstream of the dam, they have been judged unacceptable to fishery managers responsible for perpetuating the fishery in Lake Roosevelt. In an effort to reduce fish entrainment rates, the scope of work for the Chief Joseph Kokanee Enhancement Project was modified in 2001 to include a multiyear study of the efficacy of using strobe lights to deter fish from entering the third powerplant forebay. Pacific Northwest National Laboratory initiated the four-year study in collaboration with Colville Tribal

  13. The Use and Perceived Utility of Peer Mediated Support Systems for School Psychologists: A Commentary on "Introduction to Developing Peer-Mediated Support Systems for Helping Professionals: Are We Ready to Practice What We Preach," an article by Joseph E. Zins, and on "Consultation with Professional Peers: A National Survey of the Practices of School Psychologists," an article by Joseph E. Zins and John J. Murphy

    ERIC Educational Resources Information Center

    Cowan, Richard J.

    2007-01-01

    This commentary discusses two seminal articles highlighting Joseph Zins' perspective about the potential utility and advantages of peer-mediated support groups (PSGs) to foster ongoing professional development, support, and career enhancement for school psychologists. Specifically, it discusses past, present and future applications of PSGs for…

  14. The first demonstration of lactic acid in human blood in shock by Johann Joseph Scherer (1814–1869) in January 1843

    PubMed Central

    Jansen, T. C.; van der Hoven, B.; Bakker, J.

    2007-01-01

    Lactic acid was first found and described in sour milk by Karl Wilhelm Scheele (1742–1786) in 1780. The German physician–chemist Johann Joseph Scherer (1841–1869) demonstrated the occurrence of lactic acid in human blood under pathological conditions in 1843 and 1851. In this article we honour the forgotten observations by Scherer and describe the influence of Scherer's finding on further research on lactic acid at the end of the 19th century. We conclude that Scherer's 1843 case reports should be cited as the first description of lactic acid in human blood after death and also as the first demonstration of lactic acid as a pathological finding in septic and haemorrhagic shock. Carl Folwarczny was, in 1858, the first to demonstrate lactic acid in blood in a living patient. PMID:17661014

  15. Joseph Priestley Across Theology, Education, and Chemistry: An Interdisciplinary Case Study in Epistemology with a Focus on the Science Education Context

    NASA Astrophysics Data System (ADS)

    de Berg, Kevin C.

    2011-07-01

    This paper discusses the findings of a search for the intellectual tools used by Joseph Priestley (1733-1804) in his chemistry, education, and theology documents. Priestley's enquiring democratic view of knowledge was applicable in all three areas and constitutes a significant part of his lifework. Current epistemological issues in science education are examined from the point of view of the nature of theory and experiment as observed in Priestley's writings and as espoused in modern philosophy of science. Science and religious faith issues in the context of science education are examined from the point of view of one's understanding of sacred texts, and the suggestion is made that a Priestleyan model of "the liberty to think for oneself" and "to hold knowledge with humility and virtue" could prove helpful in dealing with the known divergent opinions in relation to science, education, and religion.

  16. The Thompson-McFadden Commission and Joseph Goldberger: Contrasting 2 Historical Investigations of Pellagra in Cotton Mill Villages in South Carolina

    PubMed Central

    Mooney, Stephen J.; Knox, Justin; Morabia, Alfredo

    2014-01-01

    As pellagra reached epidemic proportions in the United States in the early 20th century, 2 teams of investigators assessed its incidence in cotton mill villages in South Carolina. The first, the Thompson-McFadden Commission, concluded that pellagra was likely infectious. The second, a Public Health Service investigation led by Joseph Goldberger, concluded that pellagra was caused by a dietary deficiency. In this paper, we recount the history of the 2 investigations and consider how the differences between the 2 studies' designs, measurements, analyses, and interpretations led to different conclusions. Because the novel dietary assessment strategy was a key feature of the Public Health Service's study design, we incorporated simulated measurement error in a reanalysis of the Public Health Service's data to assess whether this specific difference affected the divergent conclusions. PMID:24966221

  17. Chief Joseph Kokanee Enhancement Project; Strobe Light Deterrent Efficacy Test and Fish Behavior Determination at the Grand Coulee Dam Third Powerplant Forebay, 2003-2004 Annual Report.

    SciTech Connect

    Simmons, M.; McKinstry, C.; Cook, C.

    2004-01-01

    Since 1995, the Confederated Tribes of the Colville Reservation (Colville Confederated Tribes) have managed the Chief Joseph Kokanee Enhancement Project as part of the Northwest Power Planning Council (NWPPC) Fish and Wildlife Program. Project objectives have focused on understanding natural production of kokanee (a land-locked sockeye salmon) and other fish stocks in the area above Grand Coulee and Chief Joseph Dams on the Columbia River. A 42-month investigation from 1996 to 1999 determined that from 211,685 to 576,676 fish were entrained annually at Grand Coulee Dam. Analysis of the entrainment data found that 85% of the total entrainment occurred at the dam's third powerplant. These numbers represent a significant loss to the tribal fisheries upstream of the dam. In response to a suggestion by the NWPPC Independent Scientific Review Panel, the scope of work for the Chief Joseph Kokanee Enhancement Project was expanded to include a multiyear pilot test of a strobe light system to help mitigate fish entrainment. This report details the work conducted during the third year of the strobe light study by researchers of the Colville Confederated Tribes in collaboration with the Pacific Northwest National Laboratory. The objective of the study is to determine the efficacy of a prototype strobe light system to elicit a negative phototactic response in kokanee and rainbow trout under field conditions. The prototype system consists of six strobe lights affixed to an aluminum frame suspended 15 m vertically underwater from a barge secured in the center of the entrance to the third powerplant forebay. The lights, controlled by a computer, illuminate a region directly upstream of the barge. The 2003 study period extended from June 16 through August 1. Three light treatments were used: all six lights on for 24 hours, all lights off for 24 hours, and three of six lights cycled on and off every hour for 24 hours. These three treatment conditions were assigned randomly within a

  18. Chief Joseph Kokanee Enhancement Project : Strobe Light Deterrent Efficacy Test and Fish Behavior Determination at Grond Coulee Dam Third Powerplant Forebay.

    SciTech Connect

    Simmons, M.A.; McKinstry, C.A.; Simmons, C.S.

    2002-01-01

    Since 1995, the Colville Confederated Tribes have managed the Chief Joseph Kokanee Enhancement Project as part of the Northwest Power Planning Council's (NWPPC) Fish and Wildlife Program. Project objectives have focused on understanding natural production of kokanee (a land-locked sockeye salmon) and other fish stocks in the area above Grand Coulee and Chief Joseph Dams on the Columbia River. A 42-month investigation concluded that entrainment at Grand Coulee Dam ranged from 211,685 to 576,676 fish annually. Further analysis revealed that 85% of the total entrainment occurred at the dam's third powerplant. These numbers represent a significant loss to the tribal fisheries upstream of the dam. In response to a suggestion by the NWPPC's Independent Scientific Review Panel, the scope of work for the Chief Joseph Kokanee Enhancement Project was expanded to include a multiyear pilot test of a strobe light system to help mitigate fish entrainment. This report details the work conducted during the first year of the study by researchers of the Colville Confederated Tribes in collaboration with the Pacific Northwest National Laboratory (PNNL). The objective of the study was to determine the efficacy of a prototype strobe light system to elicit a negative phototactic response in kokanee and rainbow trout. Analysis of the effect of strobe lights on the distribution (numbers) and behavior of kokanee and rainbow trout was based on 51, 683 fish targets detected during the study period (June 30 through August 1, 2001). Study findings include the following: (1) Analysis of the count data indicated that significantly more fish were present when the lights were on compared to off. This was true for both the 24-hr tests as well as the 1-hr tests. Powerplant discharge, distance from lights, and date were significant factors in the analysis. (2) Behavioral results indicated that fish within 14 m of the lights were trying to avoid the lights by swimming across the lighted region or

  19. Joseph-Nicolas Delisle's relations with German astronomers and scientists when travelling to and from Russia (1725-26 and 1747)

    NASA Astrophysics Data System (ADS)

    Dumont, Simone

    Upon request by Peter-the-Great, the French astronomer Joseph-Nicolas Delisle (1688-1768) left Paris in November 1725. During his voyage, he wanted to visit German colleagues and to have the opportunity to examine their instruments. His objective since several years was to collect original data of observations. When being in Nuremberg and Berlin, he made a search concerning the observations performed by Eimmart and G. Kirch, later in Danzig, he succeeded to buy Hevelius's manuscripts. After staying in Russia for 22 years, where he was the founder of the Petersburg Observatory, Delisle came back to France in the year 1747. During his return trip (two and a half months) he visited libraries in Prussia showing interest to their manuscripts and to some curiosities. Then in the surroundings of Wittenberg, he visited count von Löser's collection of instruments. In Berlin, he met the Feldmarschall von Schmettau and Grischow; but the previously seen colleagues were dead. During all these years, Delisle had enlarged the circle of his acquaintances, which has been very useful to launch the ``avertissements'' to recommend observations of some peculiar astronomical phenomena. The expeditions in 1761 for the transit of Venus owe a lot to him.

  20. Medical doctors as the captain of a ship: an analysis of medical students’ book reports on Joseph Conrad’s “Lord Jim”

    PubMed Central

    2014-01-01

    Purpose: In South Korean ferry disaster in 2014, the captain abandoned the ship with passengers including high school students still aboard. We noticed the resemblance of abandoning the ship with passengers still aboard the ferry (named the Sewol) and the ship Patna, which was full of pilgrims, in Joseph Conrad’s novel “Lord Jim.” The aim of this study is to see how medical students think about the role of a medical doctor as a captain of a ship by analyzing book reports on Conrad’s “Lord Jim.” Methods: Participants included 49 third-year medical students. Their book reports were analyzed. Results: If placed in the same situation as the character of Jim, 24 students of the 49 respondents answered that they would stay with the passengers, while 18 students indicated they would escape from the ship with the crew. Most of the students thought the role of a doctor in the medical field was like that of a ‘captain.’ The medical students reported that they wanted to be a doctor who is responsible for his or her patients, highly moral, warm-hearted, honest, and with high self-esteem. Conclusion: In conclusion, we found that “Lord Jim” induced the virtue of ‘responsibility’ from the medical students. Consequently, “Lord Jim” could be good teaching material for medical humanities. PMID:25417908

  1. Monsters and the case of L. Joseph: André Feil's thesis on the origin of the Klippel-Feil syndrome and a social transformation of medicine.

    PubMed

    Belykh, Evgenii; Malik, Kashif; Simoneau, Isabelle; Yagmurlu, Kaan; Lei, Ting; Cavalcanti, Daniel D; Byvaltsev, Vadim A; Theodore, Nicholas; Preul, Mark C

    2016-07-01

    André Feil (1884-1955) was a French physician best recognized for his description, coauthored with Maurice Klippel, of patients with congenital fusion of cervical vertebrae, a condition currently known as Klippel-Feil syndrome. However, little is known about his background aside from the fact that he was a student of Klippel and a physician who took a keen interest in describing congenital anomalies. Despite the relative lack of information on Feil, his contributions to the fields of spinal disease and teratology extended far beyond science to play an integral role in changing the misguided perception shrouding patients with disfigurements, defects, deformities, and so-called monstrous births. In particular, Feil's 1919 medical school thesis on cervical abnormalities was a critical publication in defying long-held theory and opinion that human "monstrosities," anomalies, developmental abnormalities, and altered congenital physicality were a consequence of sinful behavior or a reversion to a primitive state. Indeed, his thesis on a spinal deformity centering on his patient, L. Joseph, was at the vanguard for a new view of a patient as nothing less than fully human, no matter his or her physicality or appearance. PMID:27364256

  2. Treating Palliative Care Patients with Pain with the Body Tambura: A Prospective Case Study at St. Joseph's Hospice for Dying destitute in Dindigul South India

    PubMed Central

    Dietrich, Cordula; Teut, M; Samwel, Kakuko Lopoyetum; Narayanasamy, S; Rathapillil, T; Thathews, G

    2015-01-01

    Background: The Body Tambura is a recently invented stringed instrument that is used for receptive music therapy designed to be placed and attached on the human body. The aim of this study was to record perceived effects of a treatment with the Body Tambura on palliative care patients with special reference to pain. Materials and Methods: A prospective case study was carried out with patients of St. Joseph's Hospice for Dying Destitute in Dindigul/South India. Patients were treated with a treatment after baseline assessment and also on the next day. Outcomes were measured quantitatively by using a numeric rating scale (0–10, 10 maximum intensity of pain felt) at baseline, directly after treatment, and the day after the treatment to determine the intensity of the pain. Results: Ten patients (five women and five men) participated in the study. The majority described the therapy as a pleasant experience. The pain intensity at baseline was reduced from 8.3 ± standard deviation (SD) 1.16 to 4.6 ± 1.52 at day 1 and from 4.6 ± 2.07 to 2.4 ± 1.58 at day 2. Conclusion: A clinically relevant pain reduction was described as short time outcome; the therapy was received and perceived well. Forthcoming research should include a control group, randomization, a larger number of participants, and a longer period of treatment. PMID:26009680

  3. Application of the FluEgg model to predict transport of Asian carp eggs in the Saint Joseph River (Great Lakes tributary)

    USGS Publications Warehouse

    Garcia, Tatiana; Murphy, Elizabeth A.; Jackson, P. Ryan; Garcia, Marcelo H.

    2015-01-01

    The Fluvial Egg Drift Simulator (FluEgg) is a three-dimensional Lagrangian model that simulates the movement and development of Asian carp eggs until hatching based on the physical characteristics of the flow field and the physical and biological characteristics of the eggs. This tool provides information concerning egg development and spawning habitat suitability including: egg plume location, egg vertical and travel time distribution, and egg-hatching risk. A case study of the simulation of Asian carp eggs in the Lower Saint Joseph River, a tributary of Lake Michigan, is presented. The river hydrodynamic input for FluEgg was generated in two ways — using hydroacoustic data and using HEC-RAS model data. The HEC-RAS model hydrodynamic input data were used to simulate 52 scenarios covering a broad range of flows and water temperatures with the eggs at risk of hatching ranging from 0 to 93% depending on river conditions. FluEgg simulations depict the highest percentage of eggs at risk of hatching occurs at the lowest discharge and at peak water temperatures. Analysis of these scenarios illustrates how the interactive relation among river length, hydrodynamics, and water temperature influence egg transport and hatching risk. An improved version of FluEgg, which more realistically simulates dispersion and egg development, is presented. Also presented is a graphical user interface that facilitates the use of FluEgg and provides a set of post-processing analysis tools to support management decision-making regarding the prevention and control of Asian carp reproduction in rivers with or without Asian carp populations.

  4. Combined therapy with m-TOR-dependent and -independent autophagy inducers causes neurotoxicity in a mouse model of Machado-Joseph disease.

    PubMed

    Duarte-Silva, S; Silva-Fernandes, A; Neves-Carvalho, A; Soares-Cunha, C; Teixeira-Castro, A; Maciel, P

    2016-01-28

    A major pathological hallmark in several neurodegenerative disorders, like polyglutamine disorders (polyQ), including Machado-Joseph disease (MJD), is the formation of protein aggregates. MJD is caused by a CAG repeat expansion in the ATXN3 gene, resulting in an abnormal protein, which is prone to misfolding and forms cytoplasmic and nuclear aggregates within neurons, ultimately inducing neurodegeneration. Treatment of proteinopathies with drugs that up-regulate autophagy has shown promising results in models of polyQ diseases. Temsirolimus (CCI-779) inhibits the mammalian target of rapamycin (m-TOR), while lithium chloride (LiCl) acts by inhibiting inositol monophosphatase, both being able to induce autophagy. We have previously shown that chronic treatment with LiCl (10.4 mg/kg) had limited effects in a transgenic MJD mouse model. Also, others have shown that CCI-779 had mild positive effects in a different mouse model of the disease. It has been suggested that the combination of mTOR-dependent and -independent autophagy inducers could be a more effective therapeutic approach. To further explore this avenue toward therapy, we treated CMVMJD135 transgenic mice with a conjugation of CCI-779 and LiCl, both at concentrations known to induce autophagy and not to be toxic. Surprisingly, this combined treatment proved to be deleterious to both wild-type (wt) and transgenic animals, failing to rescue their neurological symptoms and actually exerting neurotoxic effects. These results highlight the possible dangers of manipulating autophagy in the nervous system and suggest that a better understanding of the potential disruption in the autophagy pathway in MJD is required before successful long-term autophagy modulating therapies can be developed. PMID:26601773

  5. Toward therapeutic targets for SCA3: Insight into the role of Machado-Joseph disease protein ataxin-3 in misfolded proteins clearance.

    PubMed

    Li, Xiaoling; Liu, Hongmei; Fischhaber, Paula L; Tang, Tie-Shan

    2015-09-01

    Machado-Joseph disease (MJD, also known as spinocerebellar ataxia type 3, SCA3), an autosomal dominant neurological disorder, is caused by an abnormal expanded polyglutamine (polyQ) repeat in the ataxin-3 protein. The length of the expanded polyQ stretch correlates positively with the severity of the disease and inversely with the age at onset. To date, we cannot fully explain the mechanism underlying neurobiological abnormalities of this disease. Yet, accumulating reports have demonstrated the functions of ataxin-3 protein in the chaperone system, ubiquitin-proteasome system, and aggregation-autophagy, all of which suggest a role of ataxin-3 in the clearance of misfolded proteins. Notably, the SCA3 pathogenic form of ataxin-3 (ataxin-3(exp)) impairs the misfolded protein clearance via mechanisms that are either dependent or independent of its deubiquitinase (DUB) activity, resulting in the accumulation of misfolded proteins and the progressive loss of neurons in SCA3. Some drugs, which have been used as activators/inducers in the chaperone system, ubiquitin-proteasome system, and aggregation-autophagy, have been demonstrated to be efficacious in the relief of neurodegeneration diseases like Huntington's disease (HD), Parkinson's (PD), Alzheimer's (AD) as well as SCA3 in animal models and clinical trials, putting misfolded protein clearance on the list of potential therapeutic targets. Here, we undertake a comprehensive review of the progress in understanding the physiological functions of ataxin-3 in misfolded protein clearance and how the polyQ expansion impairs misfolded protein clearance. We then detail the preclinical studies targeting the elimination of misfolded proteins for SCA3 treatment. We close with future considerations for translating these pre-clinical results into therapies for SCA3 patients. PMID:26123252

  6. Non-Mendelian transmission in dentatorubral-pallidoluysian atrophy and Machado-Joseph disease: the mutant allele is preferentially transmitted in male meiosis.

    PubMed Central

    Ikeuchi, T.; Igarashi, S.; Takiyama, Y.; Onodera, O.; Oyake, M.; Takano, H.; Koide, R.; Tanaka, H.; Tsuji, S.

    1996-01-01

    Autosomal dominant dentatorubral-pallidoluysian atrophy (DRPLA) and Machado-Joseph disease (MJD) are neurodegenerative disorders caused by CAG trinucleotide repeat expansions. An inverse correlation of age at onset with the length of the expanded CAG trinucleotide repeats has been demonstrated, and the intergenerational instability of the length of the CAG trinucleotide repeats, which is more prominent in paternal than in maternal transmissions, has been shown to underlie the basic mechanisms of anticipation in DRPLA and MJD. Our previous observations on DRPLA and MJD pedigrees, as well as a review of the literature, have suggested that the numbers of affected offspring exceed those of unaffected offspring, which is difficult to explain by the Mendelian principle of random segregation of alleles. In the present study, we analyzed the segregation patterns in 211 transmissions in 24 DRPLA pedigrees and 80 transmissions in 7 MJD pedigrees, with the diagnoses confirmed by molecular testing. Significant distortions in favor of transmission of the mutant alleles were found in male meiosis, where the mutant alleles were transmitted to 62% of all offspring in DRPLA (chi2 = 7.69; P<.01) and 73% in MJD (chi2 = 6.82; P<.01). The results were consistent with meiotic drive in DRPLA and MJD. Since more prominent meiotic instability of the length of the CAG trinucleotide repeats is observed in male meiosis than in female meiosis and meiotic drive is observed only in male meiosis, these results raise the possibility that a common molecular mechanism underlies the meiotic drive and the meiotic instability in male meiosis. PMID:8644735

  7. Non-Mendelian transmission in dentatorubral-pallidolysian atrophy and Machado-Joseph disease: The mutant allele is preferentially transmitted in male meiosis

    SciTech Connect

    Ikeuchi, Takeshi; Igarashi, Shuichi; Takiyama, Yoshihisa; Onodera, Osamu

    1996-04-01

    Autosomal dominant dentatorubral-pallidoluysian atrophy (DRPLA) and Machado-Joseph disease (MJD) are neurodegenerative disorders caused by CAG trinucleotide repeat expansions. An inverse correlation of age at onset with the length of the expanded CAG trinucleotide repeats has been demonstrated, and the intergenerational instability of the length of the CAG trinucleotide repeats, which is more prominent in paternal than in maternal transmissions, has been shown to underlie the basic mechanisms of anticipation in DRPLA and MJD. Our previous observations on DRPLA and MJD pedigrees, as well as a review of the literature, have suggested that the numbers of affected offspring exceed those of unaffected offspring, which is difficult to explain by the Mendelian principle of random segregation of alleles. In the present study, we analyzed the segregation patterns in 211 transmissions in 24 DRPLA pedigrees and 80 transmissions in 7 MJD pedigrees, with the diagnoses confirmed by molecular testing. Significant distortions in favor of transmission of the mutant alleles were found in male meiosis, where the mutant alleles were transmitted to 62% of all offspring in DRPLA ({chi}{sup 2} = 7.69; P < .01) and 73% in MJD ({chi}{sup 2} = 6.82; P < .01). The results were consistent with meiotic drive in DRPLA and MJD. Since more prominent meiotic instability of the length of the CAG trinucleotide repeats is observed in male meiosis than in female meiosis and meiotic drive is observed only in male meiosis, these results raise the possibility that a common molecular mechanism underlies the meiotic drive and the meiotic instability in male meiosis. 23 refs., 1 tab.

  8. Psychological Well-Being and Family Satisfaction Levels Five Years After Being Confirmed as a Carrier of the Machado-Joseph Disease Mutation

    PubMed Central

    Gonzalez, Carlos; Gomes, Elisabete; Kazachkova, Nadiya; Bettencourt, Conceição; Raposo, Mafalda; Kay, Teresa Taylor; MacLeod, Patrick; Vasconcelos, João

    2012-01-01

    The present study on long-term outcome of presymptomatic testing for Machado-Joseph disease (MJD) aimed to evaluate the psychological well-being and the familial satisfaction of subjects that 5 years prior received an unfavorable result in the predictive testing (PT). The study included 47 testees of Azorean origin (23 from the island of Flores and 24 from S. Miguel) that completed the fourth evaluation session of the MJD protocol, and undertook a neurological examination at the moment of participation in the study. Nearly 50% of testees were symptomatic at the time of the study. Psychological well-being of the 47 participants was evaluated using the Psychological General Well-Being Index (PGWB). The family satisfaction scale by adjectives was applied to obtain information on family dynamics. The average PGWB score of the total participants was of 73.3, a value indicative of psychological well-being. Nearly half of the testees presented scores indicating psychological well-being, whereas scores indicating moderate (28.9%) or severe (23.7%) stress were found in the remaining. The average score in the PGWB scale was lower in symptomatic than in asymptomatic subjects; moreover, the distinct distribution of the well-being categories seen in the two groups shows an impact of the appearance of first symptoms on the psychological state. Motives for undertaking the test, provided 5 years prior, failed to show an impact in well-being. The average score for familial satisfaction was of 134, a value compatible with high familial satisfaction, which represented the most frequent category (59.6%). Results demonstrate that well-being and family satisfaction need to be monitored in confirmed carriers of the MJD mutation. The inclusion of acceptance studies, after PT, as well as the development of acceptance training actions, should be of major importance to anticipate the possibility of psychological damage. PMID:23153003

  9. Late-Quaternary morphostratigraphy of Lake St-Joseph (southeastern Canadian Shield): Evolution from a semi-enclosed glacimarine basin to a postglacial lake

    NASA Astrophysics Data System (ADS)

    Normandeau, Alexandre; Lajeunesse, Patrick; Philibert, Geneviève

    2013-09-01

    This paper reports and describes multibeam echosounder, subbottom profiler and sediment sampling data collected in Lake St-Joseph (southern Québec), a formerly glacimarine sedimentary basin that has been glacio-isostatically uplifted to form a small lake. Its study provides a unique opportunity for investigating changes in sedimentary environments from a glacial sea to a postglacial lake. Multibeam bathymetry allows the observation of two basins separated by a bathymetric ridge and of mass movement deposits in both basins. High resolution seismic stratigraphy reveals the presence of seven seismic units. These seven units relate to the advance and retreat of the Laurentide ice-sheet over the region. Following ice-retreat, transparent (U3) and high amplitude reflection (U4) units were deposited during the Champlain Sea invasion. The transparent unit likely represents a rapidly retreating glacier, which allowed the deposition of massive silt and clay, whereas the high amplitude reflectors, which are internally composed of transparent to chaotic lenses, are interpreted as the result of a deceleration of ice-retreat or a stabilization of the glacier and of glacio-isostatic rebound. Overlying the Champlain Sea sediments, a unit composed of smaller laminations (U5) suggests that it was deposited during the marine to lacustrine transition, in a paraglacial environment. This is supported by its presence in the northern basin, where the Rivière-aux-Pins mouth is located and its absence in the southern basin, where no river is observed. The bathymetric ridge between the two basins thus limited sediment transport. Following the complete retreat of the Champlain Sea, organic-rich sediments (U7) were deposited in the lake. In the northern basin, the presence of the Rivière-aux-Pins allowed their deposition in the form of rhythmites whereas the absence of rivers in the southern basin resulted in the deposition of an acoustically transparent unit. A mass movement (U6

  10. Joseph Priestley and His Contemporaries

    ERIC Educational Resources Information Center

    Porter, George

    1975-01-01

    Author recalled simultaneously the scientific lives of Priestley, Franklin, Rumford, Davy, Faraday, and other investigators of "experimental philosophy" (what we now call chemistry), and the life of the Royal Institution, founded in 1797 to promote both research and its practical applications. (Editor/RK)

  11. Larmor, Joseph (1857-1942)

    NASA Astrophysics Data System (ADS)

    Murdin, P.

    2000-11-01

    Physicist, born in Magheragall, County Antrim, Ireland, became Lucasian professor in Cambridge, working on electricity, dynamics and thermodynamics, and especially the ether, the postulated material which pervades space and in which electromagnetic radiation travels. Finding no evidence that the ether existed, he was led to some of the results inherent in EINSTEIN's theory of relativity, giving a...

  12. Cultivating Fertile Grounds: Enhancing and Extending the Scientific Base of Social and Emotional Learning--A Commentary on "The Scientific Base Linking Social and Emotional Learning to School Success," a Chapter by Joseph E. Zins, Michelle R. Bloodworth, Roger P. Weissberg, and Herbert J. Walberg

    ERIC Educational Resources Information Center

    Manz, Patricia H.

    2007-01-01

    Joseph Zins was a forerunner in empirically demonstrating the interrelationship of SEL interventions and school success. This commentary highlights his perspectives on the accumulating body of evidence for the academic gains that have been associated with various SEL interventions and aims to show how new research methodologies can further extend…

  13. Talking the Higgs Boson with Dr. Joseph Incandela: Third Lecture in the DOE Science Speaker Series (includes opening remarks from Dr. Bill Brinkman and introduction by Energy Secretary, Dr. Steven Chu)

    SciTech Connect

    Incandela, Joseph

    2012-09-14

    In July of 2012, scientists leading two different research teams, working independently of each other, announced that they had almost certain proof of the long-sought Higgs boson. Though Cern did not call the discovery "official", many physicists conceded the evidence was now so compelling they had surely found the missing particle. The formal confirmation will come over the next few months of further investigation. The experiments are taking place at the Large Hadron Collider (LHC), and this third lecture in the DOE Science Speaker Series is given by one of those announcing scientists in July. He is Dr. Joseph Incandela, the current spokesperson for the Compact Muon Solenoid (CMS) Experiment at CERN. He was heavily involved in the search for the top quark at Fermi and is from the University of California, Santa Barbara. The title he gives his presentation is "Searching for the genetic code of our universe: Discovery at the LHC."

  14. Chief Joseph Kokanee Enhancement Project; Strobe Light Deterrent Efficacy Test and Fish Behavior Determination at Grand Coulee Dam Third Powerplant Forebay, 2005-2006 Annual Report.

    SciTech Connect

    Simmons, M.; Johnson, Robert; McKinstry, C.

    2006-03-01

    The construction of Grand Coulee and Chief Joseph dams on the Columbia River resulted in the complete extirpation of the anadromous fishery upstream of these structures. Today, this area is totally dependent upon resident fish resources to support local fisheries. The resident fishing is enhanced by an extensive stocking program for target species in the existing fishery, including kokanee (Oncorhynchus nerka kennerlyi) and rainbow trout (O. mykiss). The kokanee fishery in Lake Roosevelt has not been meeting the return goals set by fisheries managers despite the stocking program. Investigations of physical and biological factors that could affect the kokanee population found predation and entrainment had a significant impact on the fish population. In 1999 and 2000, walleye (Sander vitreum) consumed between 15% and 9%, respectively, of the hatchery kokanee within 41 days of their release, while results from a study in the late 1990s estimated that entrainment at Grand Coulee Dam could account for up to 30% of the total mortality of the stocked fish. To address the entrainment loss, the Bonneville Power Administration commissioned a study to determine if fish would avoid areas illuminated by strobe lights in the forebay of the third powerplant. This work was conducted by Pacific Northwest National Laboratory (PNNL) in conjunction with the Confederated Tribes of the Colville Reservation (Colville Confederated Tribes). From 2002 through 2004, six strobe lights were suspended in the center of the opening to the third powerplant forebay during summer months. Results from those studies indicated that fish appeared to be attracted to the illuminated area but only at night and when flow conditions within the third powerplant forebay were minimal. However, small but consistent results from these studies indicated that under high flow conditions, fish might be avoiding the lights. The 2005 study was designed to examine whether, under high flow conditions near the penstock

  15. Using 3D Acoustic Telemetry to Assess the Response of Resident Salmonids to Strobe Lights in Lake Roosevelt, Washington; Chief Joseph Kokanee Enhancement Feasibility Study, Annual Report 2001-2002.

    SciTech Connect

    Perry, Russlee; Farley, M.; Hansen, Gabriel

    2003-01-01

    In 1995, the Chief Joseph Kokanee Enhancement Project was established to mitigate the loss of anadromous fish due to the construction of Chief Joseph and Grand Coulee dams. The objectives of the Chief Joseph Enhancement Project are to determine the status of resident kokanee (Oncorhynchus nerka) populations above Chief Joseph and Grand Coulee dams and to enhance kokanee and rainbow trout (Oncorhynchus mykiss) populations. Studies conducted at Grand Coulee Dam documented substantial entrainment of kokanee through turbines at the third powerhouse. In response to finding high entrainment at Grand Coulee Dam, the Independent Scientific Review Panel (ISRP) recommended investigating the use of strobe lights to repel fish from the forebay of the third powerhouse. Therefore, our study focused on the third powerhouse and how strobe lights affected fish behavior in this area. The primary objective of our study was to assess the behavioral response of kokanee and rainbow trout to strobe lights using 3D acoustic telemetry, which yields explicit spatial locations of fish in three dimensions. Our secondary objectives were to (1) use a 3D acoustic system to mobile track tagged fish in the forebay and upriver of Grand Coulee Dam and (2) determine the feasibility of detecting fish using a hydrophone mounted in the tailrace of the third powerhouse. Within the fixed hydrophone array located in the third powerhouse cul-de-sac, we detected 50 kokanee and 30 rainbow trout, accounting for 47% and 45% respectively, of the fish released. Kokanee had a median residence time of 0.20 h and rainbow trout had a median residence time of 1.07 h. We detected more kokanee in the array at night compared to the day, and we detected more rainbow trout during the day compared to the night. In general, kokanee and rainbow trout approached along the eastern shore and the relative frequency of kokanee and rainbow trout detections was highest along the eastern shoreline of the 3D array. However, because we

  16. Joseph Henry and the American Philosophical Society

    ERIC Educational Resources Information Center

    Gross, Walter E.

    1972-01-01

    A study of the extent to which Henry was affiliated with the Society and its influence on his work including his evolving relationship with the Society in the scope of the changing nature of American scientific institutions. (DF)

  17. Joseph Tofte Bruns: Wrestling with Big Ideas

    ERIC Educational Resources Information Center

    Cosier, Kimberly

    2010-01-01

    Joe Bruns is currently a student in the Post-Baccalaureate Teacher Certification Program at the University of Wisconsin-Milwaukee. The series of work featured in this interview centers on the idea of relationships. Joe explores collective and implicated relationship to the work of Felix Gonzalez-Torres through the reuse of paper taken from…

  18. Pawsey, Joseph Lade (1908-62)

    NASA Astrophysics Data System (ADS)

    Murdin, P.

    2000-11-01

    Radiophysicist and astronomer, born Ararat, Victoria, Australia, pioneered the use of a Lloyd's mirror arrangement for radio interferometry at Dover Heights in Australia, and located the source of solar radio noise within the disc of the Sun. As John Hey had suggested, the radio noise came from sunspots....

  19. An Interview with Sir Keith Joseph.

    ERIC Educational Resources Information Center

    Special Education: Forward Trends, 1983

    1983-01-01

    The interview with Britain's Secretary of State for Education focuses on special education policies, includng such topics as the role of microelectronics, parent participation, services for integrated students, and curriculum development for children with moderate learning difficultties. (CL)

  20. Inflammation, suppuration, putrefaction, fermentation: Joseph Lister's microbiology

    PubMed Central

    Richardson, Ruth

    2013-01-01

    This paper focuses on Lister's inaugural lecture at King's College, London, in October 1877. As the new Professor of Clinical Surgery, Lister had much to report, including impressively high survival rates from complex operations previously regarded as foolhardy. Instead, he chose to address the processes of fermentation in wine, blood and milk. His reasons are not obvious to a modern audience, just as they probably were not to those who heard him in the Great Hall at King's. Having brought microbiological apparatus from his laboratory to the lecture theatre and presented proof of bacterial variety and specificity, Lister publicly demonstrated the creation of the first pure bacterial culture in the history of microbiology. It was an ingenious and well-thought-out strategy designed to generate a frame of mind among his new colleagues and future students, receptive to the causative role of bacteria in septic diseases. His timing was impeccable.

  1. Mapping of the gene for Machado-Joseph disease within a 3.6-cM interval flanked by D14S291/D14S280 and D14S81, on the basis of studies of linkage and linkage disequilibrium in 24 Japanese families

    SciTech Connect

    Sasaki, Hidenao; Ihara, Tatsuo; Wakisaka, Akemi; Takada, Akio; Yoshiki, Takashi; Hamada, Takeshi; Suzuki, Yoshihiro; Iwabuchi, Kiyoshi; Onari, Keiko; Tada, Jyoji

    1995-01-01

    The gene locus of Machado-Joseph disease (MJD) has recently been mapped within a 29-cM subregion of 14q chromosome. We did a linkage study of 24 multigenerational MJD Japanese pedigrees, in an attempt to narrow the candidate region of this gene. Pairwise and multipoint linkage analysis, together with haplotype segregation analysis, led to the conclusion that the MJD gene is located at the 6.8-cM interval between D14S256 and D14S81 (Z{sub max} = 24.78, multipoint linkage analysis). D14S291 and D14S280, located at the center of this interval, showed no obligate recombination with the MJD gene (Z{sub max} = 5.93 for D14S291 and 9.99 for D14S280). A weak, but significant, linkage disequilibrium of MJD gene was noted with D14S81 (P<.05) but not with D14S291 or D14S280. These results suggest that a 3.6-cM interval flanked by D14S291/D14S280 and D14S81 is the most likely location of the MJD gene and that it is closest to D14S81. 33 refs., 4 figs., 6 tabs.

  2. The Life and Work of Joseph Fraunhofer (1787-1826)

    ERIC Educational Resources Information Center

    Leitner, Alfred

    1975-01-01

    Describes Fraunhofer's scientific career as a glass and lens maker, a discoverer of dark lines in the solar spectrum, a corrector of lens aberration, and investigator of diffraction. Gives biographical data and anecdotes. Includes a bibliography, mainly of German sources. (GH)

  3. Macmillan Encyclopedia of Chemistry (edited by Joseph J. Lagowski)

    NASA Astrophysics Data System (ADS)

    Kauffman, George B.

    1998-11-01

    Macmillan: New York, 1997. Four volumes. Figs., tables. lxxi + 1696 pp. 22.0 x 28.5 cm. $400. ISBN 0-02-897225-2. This latest addition to Macmillan's series of comprehensive core science encyclopedias (previous sets dealt with physics and earth sciences) will be of particular interest to readers of this Journal, for it is edited by longtime Journal of Chemical Education editor Joe Lagowski, assisted by a board of five distinguished associate editors. The attractively priced set offers clear explanations of the phenomena and concepts of chemistry and its materials, whether found in industry, the laboratory, or the natural world. It is intended for a broad spectrum of readers-professionals whose work draws on chemical concepts and knowledge (e.g., material scientists, engineers, health workers, biotechnologists, mathematicians, and computer programmers), science teachers at all levels from kindergarten to high school, high school and college students interested in medicine or the sciences, college and university professors, and laypersons desiring information on practical aspects of chemistry (e.g., household cleaning products, food and food additives, manufactured materials, herbicides, the human body, sweeteners, and animal communication).

  4. Response to a Serious Flood: The St Joseph's Healthcare Experience.

    PubMed

    Dhanoa, Tina; Fuller, Hugh; Herechuk, Bryan; Trowbridge, Stephanie; Raab, Victoria; MacDonald, Anne Marie; Coffin-Simpson, Tara; Gosse, Carolyn

    2014-01-01

    Water spread like liquid fire damaging more than 60,000 sq. ft. of clinical and support space, bringing the emergency department (ED) and operating rooms at St Joe's to an abrupt halt. Staff mobilized immediately, calling a hospital-wide Code Aqua (flood) and Code Green (evacuation) for the ED, and launching into action to save equipment and supplies worth millions of dollars. Our path to recovery has been difficult, but we have emerged stronger as an organization. The urgent necessity of rethinking care led to radical innovation, particularly in the flow and care of patients admitted through the ED. PMID:25906467

  5. 33 CFR 110.193a - St. Joseph Bay, Fla.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) Explosives Anchorage Area 1. A rectangular area 3,000 yards long by 700 yards wide beginning at a point 1,350 yards west of U.S. Highway 98 Bridge over Gulf County Canal. The area is parallel to and 450 yards... circular area with a 500-yard radius around a center point located at latitude 29°47′30″; longitude...

  6. 75 FR 32742 - Action Affecting Export Privileges; Joseph Piquet

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-09

    ... Notices, the most recent being that of August 13, 2009 (74 FR 41325, August 14, 2009), has continued the... involved in this conspiracy were high power amplifiers designed for use by the U.S. military in early warning radar and missile target acquisition systems, and low noise amplifiers that have both...

  7. A remarkable career in science-Joseph G. Gall.

    PubMed

    Endow, Sharyn A; Nizami, Zehra F; Gerbi, Susan A

    2013-07-01

    A festive group of ∼150 current and former students, postdoctoral and other associates, and colleagues gathered during the weekend of April 12-14, 2013 to celebrate Joe Gall's 85th birthday. The gathering, hosted by the Carnegie Institution for Science, Department of Embryology (Allan Spradling, Director) and organized by a group of Joe's current and former students (Zehra Nizami, Alison Singer, Ji-Long Liu, Virginia Zakian, Susan Gerbi), was held in Baltimore, MD. Dinners and symposia extending over 3 days celebrated Joe's scientific findings over the years, together with those of his former students, postdoctoral fellows, and other associates (see program at https://sites.google.com/site/gallsymposium2013/ ). PMID:23828690

  8. 33 CFR 117.651 - St. Joseph River.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... from three minutes before to three minutes after the hour and half hour, and the draw of the Bicentennial bridge need be opened only from three minutes before to three minutes after the quarter and...

  9. A King over Egypt, Which Knew Not Joseph.

    ERIC Educational Resources Information Center

    Coffman, William E.

    1993-01-01

    Although it is true that today's education needs improvement, schools today are not all bad. The opinions of the following five experts, whose views are worth hearing are introduced: (1) Thomas Hopkins; (2) Ralph Tyler; (3) E. F. Lindquist; (4) Walter Cook; and (5) Harold Benjamin. (SLD)

  10. More than a Metaphor: The Education of Joseph Knecht

    ERIC Educational Resources Information Center

    Roberts, Peter

    2008-01-01

    Education is a key theme in Hermann Hesse's final novel, "The Glass Bead Game". The book begins with a narrator's introduction, in which the Glass Bead Game is described as a way of playing with the total contents of culture--of drawing connections between disciplines, knowledge and values. The main part of the novel is devoted to the life of…

  11. Joseph Schwab, Curriculum, Curriculum Studies and Educational Reform

    ERIC Educational Resources Information Center

    Connelly, F. Michael

    2013-01-01

    The "Practical 1" paper combines Schwab's abiding concern, for the nature and quality of educational experience with another abiding concern, for how we think about what we do. The Practical 1 is the first of a set of four "practical" essays. These in turn are the product of his thinking about college education and his…

  12. Joseph A. Burton Forum Award: Some Nuclear Weapons Dilemmas

    NASA Astrophysics Data System (ADS)

    May, Michael

    2014-03-01

    Nuclear weapons pose a combination of political and ethical dilemmas the solution to which has not been found. On one hand, in the view of both US government leaders and US allies, nuclear deterrence continues to play an essential part in the US role as the ultimate source of military strength for the alliances among the major democratic countries. It also continues to be in demand by countries that believe themselves to be isolated and threatened. On the other hand, nuclear weapons, besides being effective deterrents, can cause unprecedented loss of life and risk the demise of civilizations. No ban or technical precaution could prevent the rebuilding of nuclear weapons in a crisis. No diplomatic arrangement to date has erased the threat of invasion and war in the world. Only the abandonment of war and the threat of war as instruments of policy can make nuclear weapons obsolete. The slow, halting, risky road to that end remains the only hope for a world in which lasting solutions to the nuclear dilemmas are possible.

  13. Factors Influencing Nutrient Losses in the St. Joseph River Watershed

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Agricultural drainage ditches are a common landscape feature in the glacial till soils of the upper Midwestern United States. Many of these ditches have had vegetative buffer strips placed along the banks, presumably to filter sediments and other contaminants as surface runoff flows from adjacent f...

  14. Joseph eleve des poissons au Gabon. Guide pour l'elevage des poissons (Joseph Raises Fish in Gabon. Guide for Raising Fish).

    ERIC Educational Resources Information Center

    Needham, Scott

    A guide, in French, to raising fish for food and profit is designed to instruct and encourage Gabonese natives to establish family fisheries. It describes and illustrates in story form the process used to plan the fishery, clear the land, seek help from an agricultural agent, create a dam, make compost, plan and build the pond, feed the fish,…

  15. Molecular evolution of troponin I and a role of its N-terminal extension in nematode locomotion.

    PubMed

    Barnes, Dawn E; Hwang, Hyundoo; Ono, Kanako; Lu, Hang; Ono, Shoichiro

    2016-03-01

    The troponin complex, composed of troponin T (TnT), troponin I (TnI), and troponin C (TnC), is the major calcium-dependent regulator of muscle contraction, which is present widely in both vertebrates and invertebrates. Little is known about evolutionary aspects of troponin in the animal kingdom. Using a combination of data mining and functional analysis of TnI, we report evidence that an N-terminal extension of TnI is present in most of bilaterian animals as a functionally important domain. Troponin components have been reported in species in most of representative bilaterian phyla. Comparison of TnI sequences shows that the core domains are conserved in all examined TnIs, and that N- and C-terminal extensions are variable among isoforms and species. In particular, N-terminal extensions are present in all protostome TnIs and chordate cardiac TnIs but lost in a subset of chordate TnIs including vertebrate skeletal-muscle isoforms. Transgenic rescue experiments in Caenorhabditis elegans striated muscle show that the N-terminal extension of TnI (UNC-27) is required for coordinated worm locomotion but not in sarcomere assembly and single muscle-contractility kinetics. These results suggest that N-terminal extensions of TnIs are retained from a TnI ancestor as a functional domain. © 2016 Wiley Periodicals, Inc. PMID:26849746

  16. Development of the EURITRACK tagged neutron inspection system

    NASA Astrophysics Data System (ADS)

    Perot, B.; Carasco, C.; Bernard, S.; Mariani, A.; Szabo, J.-L.; Mercier, E.; Sannie, G.; Viesti, G.; Nebbia, G.; Pesente, S.; Lunardon, M.; Moretto, S.; Fabris, D.; Zenoni, A.; Bonomi, G.; Donzella, A.; Fontana, A.; Boghen, G.; Valkovic, V.; Sudac, D.; Moszynski, M.; Batsch, T.; Gierlik, M.; Woski, D.; Klamra, W.; Isaksson, P.; Le Tourneur, P.; Lhuissier, M.; Colonna, A.; Tintori, C.; Peerani, P.; Sequeira, V.; Salvato, M.

    2007-08-01

    The EURopean Illicit TRAfficing Countermeasures Kit (EURITRACK) project is part of the 6th European Union Framework Program. It aims at developing a Tagged Neutron Inspection System (TNIS) to detect illicit materials, such as explosives and narcotics, in cargo containers. Fast neutron induced reactions produce specific gamma-rays used to determine the chemical composition of the inspected material. The associated particle technique is employed to precisely locate the interaction points of the neutrons. A new deuterium-tritium neutron generator has been developed, including a pixelized alpha particle detector. The TNIS also comprises high-efficiency fast neutron and gamma-ray detectors, a dedicated front-end electronics and an integrated software to entirely drive the system and automatically process the data. Most components have been integrated during last months at Institute Ruder Boskovic, in Zagreb, Croatia. An overview of the TNIS and of its preliminary performances is presented.

  17. Joseph Henry and John Henry Lefroy A common 19th century vision of auroral research

    NASA Astrophysics Data System (ADS)

    Silverman, S. M.

    Research on solar-terrestrial relationships today relies primarily on in situ space data. These data, however, cover only a short period of about 30 years. Many solar and related phenomena vary on much longer time scales. For the study of these, parameters such as sunspots, magnetic activity, auroral occurrence, or other proxy data are required. Historical records of aurora are particularly useful in this connection.

  18. 75 FR 73135 - Southern Nuclear Operating Company, Inc. Joseph M. Farley Nuclear Plant, Environmental Assessment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-29

    ... in the amount of design work required, design product loss due to computer hardware failures, and... project related to certain requirements in 10 CFR 73.55. Specifically, the request is to extend the..., this 19th day of November, 2010. For the Nuclear Regulatory Commission. Robert E. Martin, Sr....

  19. A Study of Ideational Metafunction in Joseph Conrad's "Heart of Darkness": A Critical Discourse Analysis

    ERIC Educational Resources Information Center

    Alaei, Mahya; Ahangari, Saeideh

    2016-01-01

    The linguistic study of literature or critical analysis of literary discourse is no different from any other textual description; it is not a new branch or a new level or a new kind of linguistics but the application of existing theories and methods (Halliday, 2002). This study intends to determine how ideology or opinion is expressed in Joseph…

  20. Joseph Constantine Carpue and the Bicentennial of the Birth of Modern Plastic Surgery.

    PubMed

    Freshwater, M Felix

    2015-08-01

    September 2014 marked the bicentennial of the birth of modern plastic surgery. It was then that Carpue began a prospective observational study of nasal reconstruction that culminated in his 1816 monograph, which caused an explosion of interest in reconstructive surgery throughout Europe. In conducting his study, Carpue demonstrated ethical standards and the power of planning a procedure. His methods to document his results accurately would remain unsurpassed until photography was adopted at the end of the 19th century. Carpue took an apocryphal story of surgery performed in India more than twenty years earlier and transformed it into the beginning of modern plastic surgery. He succeeded in a number of unrecognized tasks that are themselves landmarks not only in plastic surgical history, but surgical history: devising the first prospective observational study, using exclusion criteria, maintaining appropriate patient confidentiality, setting a standard for preoperative disclosure and ethical approval over a century before these measures were codified, having independent documentation of his preoperative and postoperative findings, devising a method to objectively monitor and document the forehead flap, and describing the potential value of tissue expansion. He shared his experience by publishing his results and by lecturing in Europe. His contemporaries recognized him for his contributions and he was honored by election to the Royal Society. Carpue launched the modern era of plastic surgery in an ethical, logical, and objective manner. While plastic surgery has changed in the last two centuries, the principles that Carpue followed remain valid. PMID:25795909

  1. ihear[R] Internet Therapy Program: A Program by St. Joseph Institute for the Deaf

    ERIC Educational Resources Information Center

    Broekelmann, Cheryl

    2012-01-01

    The ihear[R] Internet Therapy Program (ihear) provides effective, individualized, and interactive therapy that is tailored to each child's specific needs through a secure, high-quality Internet connection. The program brings listening and spoken language services directly to schools and families. The foundation for ihear is based on the St. Joseph…

  2. REM behavior disorder and excessive daytime somnolence in Machado-Joseph disease (SCA-3).

    PubMed

    Friedman, Joseph H; Fernandez, Hubert H; Sudarsky, Lewis R

    2003-12-01

    We reported previously that behavior suggestive of rapid eye movement sleep behavior disorder (RBD) was markedly increased in a small population of SCA-3 patients. We, therefore, asked patients and nonpatient attendees at an SCA-3 annual clinic to complete a questionnaire soliciting RBD-like behavior. Our results support the previous observation that RBD-like behaviors are significantly increased in SCA-3. PMID:14673890

  3. Living the Geography of Joseph and Temperance Bown. Middle Level Learning.

    ERIC Educational Resources Information Center

    Young, Katherine A.

    1998-01-01

    States that the Bown house, built in 1879 and overlooking the Oregon Trail, serves as a case study for demonstrating how historical houses can be used to teach about the past. Explains that the house is used as a living laboratory for social studies and describes the six rooms in detail. (CMK)

  4. The Art Therapist as Exhibiting Artist: Messages from Joseph Beuys, Suzi Gablik, and Donald Kuspit.

    ERIC Educational Resources Information Center

    Lachman-Chapin, Mildred

    1993-01-01

    Discusses views of art historian, artist, and art critic concerning the integration of identities of the art therapist and the exhibiting artist. Considers whether art therapist functions to serve others whereas exhibiting artist functions to serve or express himself/herself. Examines implications of the art therapist's message for the art world…

  5. The light-sensitive conductance of melanopsin-expressing Joseph and Hesse cells in amphioxus

    PubMed Central

    Pulido, Camila; Malagón, Gerardo; Ferrer, Camilo; Chen, Jun Kui; Angueyra, Juan Manuel; Nasi, Enrico

    2012-01-01

    Two types of microvillar photoreceptors in the neural tube of amphioxus, an early chordate, sense light via melanopsin, the same photopigment as in “circadian” light detectors of higher vertebrates. Because in amphioxus melanopsin activates a Gq/phospholipase C cascade, like phototransduction in arthropods and mollusks, possible commonalities in the photoconductance were investigated. Unlike other microvillar photoreceptors, reversal of the photocurrent can only be attained upon replacement of extracellular Na+. In addition to Na+, Ca2+ is also permeant, as indicated by the fact that (a) in normal ionic conditions the photocurrent remains inward at Vm > ENa; (b) in Na-free solution a small residual inward photocurrent persists at Vm near resting level, provided that Ca is present; and (c) Vrev exhibits a modest shift with [Ca]o manipulations. The unusual reversal is accounted for by an uncommonly low permeability of the light-dependent channels to K+, as [K]o only marginally affects the photocurrent amplitude and its reversal. Lanthanum and ruthenium red (RuR), two TRP channel antagonists, reversibly suppress the response to photostimulation of moderate intensity; therefore, the melanopsin-initiated cascade may recruit ion channels of the same family as those of rhabdomeric photoreceptors. With brighter lights, blockage declines, so that both La3+ and RuR induce a right shift in the sensitivity curve without a reduction of its asymptote. Nonetheless, an effect on the transduction cascade, rather than the channels, was ruled out on the basis of the voltage dependency of the blockade and the lack of effects of intracellular application of the same substances. The mechanisms of action of these antagonists thus entail a state-dependent blockade, with a higher affinity for the channel in the closed conformation. Collectively, the results indicate a kinship of the light-sensitive channels of amphioxus with those of invertebrate rhabdomeric visual cells and support the representation of this lineage of photoreceptors among chordates. PMID:22200946

  6. Joseph A. Burton Forum Award Lecture: Managing Nuclear and Biological Risks: Building Resilience through International Cooperation

    NASA Astrophysics Data System (ADS)

    Pregenzer, Arian

    2012-03-01

    International technical cooperation has long been an important nonproliferation strategy, especially since the 1990s when cooperative threat reduction (CTR) to prevent theft or illicit transfer of nuclear weapons, material and expertise in the former Soviet Union became a keystone of U.S. policy. The CTR approach expanded to include engagement with scientists and engineers with expertise relevant to biological and chemical weapons, and continued in the 2000s with efforts in Iraq and Libya, and cooperation with a wide range of countries on export control and nuclear and biological security. In general, the goal of such efforts has been to prevent proliferation or WMD terrorism. In most cases, the United States (or the West) defines the threat, and then funds partner countries to implement solutions. This presentation will argue that the future requires a new approach. Nuclear capabilities are more widely available than ever before, repercussions of the A.Q. Khan network continue to unfurl, and countries such as the DPRK engage in illicit cooperation. In addition, there has been a global boom in biotechnology with many nations, particularly across South and East Asia, investing in the biotech industry as a source of fuels, food, and materials for their rapidly expanding populations. Compared to the 1990s, today's threat is more diffuse, and the line between legitimate and illegitimate technical capability is no longer so clear. In addition, the West has many fewer resources to invest due to the global economic downturn. In this environment, full commitment of all countries that benefit from nuclear and biological advances will be required to assure the safety and security of all. Technical cooperation can continue to play an important role, but with some significant changes: First, challenges should be defined from a local perspective to ensure full commitment and participation. Second, the goal of cooperation should shift from preventing specific threats to building general capabilities to respond to a broad range of challenges as they arise. Finally, the funding model for technical cooperation should move from contractual arrangements to mutual investment and partnership, with regional approaches encouraged to add credibility, increase available resources, and help to ensure broad support.

  7. Characteristics, transport, and yield of sediment in Juday Creek, St. Joseph County, Indiana, 1993-94

    USGS Publications Warehouse

    Fowler, K.K.; Wilson, J.T.

    1995-01-01

    Surveys of the instream pond determined that the volume of sediment delivered to the pond from April 1993 to April 1994 was approximately 26,500 cubic feet. The average volume weight of the sediment was determined to be 102 pounds per cubic foot. The sediment yield for the upper reach of Juday Creek from April 1993 to April 1994 was estimated to be 48 tons per square mile.

  8. Joseph Constantine Carpue and the Bicentennial of the Birth of Modern Plastic Surgery

    PubMed Central

    Freshwater, M. Felix

    2015-01-01

    September 2014 marked the bicentennial of the birth of modern plastic surgery. It was then that Carpue began a prospective observational study of nasal reconstruction that culminated in his 1816 monograph, which caused an explosion of interest in reconstructive surgery throughout Europe. In conducting his study, Carpue demonstrated ethical standards and the power of planning a procedure. His methods to document his results accurately would remain unsurpassed until photography was adopted at the end of the 19th century. Carpue took an apocryphal story of surgery performed in India more than twenty years earlier and transformed it into the beginning of modern plastic surgery. He succeeded in a number of unrecognized tasks that are themselves landmarks not only in plastic surgical history, but surgical history: devising the first prospective observational study, using exclusion criteria, maintaining appropriate patient confidentiality, setting a standard for preoperative disclosure and ethical approval over a century before these measures were codified, having independent documentation of his preoperative and postoperative findings, devising a method to objectively monitor and document the forehead flap, and describing the potential value of tissue expansion. He shared his experience by publishing his results and by lecturing in Europe. His contemporaries recognized him for his contributions and he was honored by election to the Royal Society. Carpue launched the modern era of plastic surgery in an ethical, logical, and objective manner. While plastic surgery has changed in the last two centuries, the principles that Carpue followed remain valid. PMID:25795909

  9. A bill for the relief of Joseph Gabra and Sharon Kamel.

    THOMAS, 113th Congress

    Sen. Feinstein, Dianne [D-CA

    2013-03-18

    03/18/2013 Read twice and referred to the Committee on the Judiciary. (text of measure as introduced: CR S1898-1899) (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  10. A bill for the relief of Joseph Gabra and Sharon Kamel.

    THOMAS, 112th Congress

    Sen. Feinstein, Dianne [D-CA

    2011-03-02

    03/02/2011 Read twice and referred to the Committee on the Judiciary. (text of measure as introduced: CR S1137) (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  11. Joseph A. Burton Forum Award Talk: Science and Subversion -- Experiences from Pakistan

    NASA Astrophysics Data System (ADS)

    Hoodbhoy, Pervez

    2010-02-01

    How may one exorcise the twin demons that plague human society: irrational beliefs derived from faith, and of violence and militarism? The hope for a better future goes something like this: if a society is convinced that it must develop science because it wants technology, then the teaching of science is allowed even in societies where the scientific method is not wholly welcome. Therefore, because critical inquiry is its basic tool, science can be a Trojan Horse that silently subverts and ultimately helps to win the battle for secular humanism and peace. To what extent are such hopes realistic? I shall draw upon my experiences in Pakistan to argue that good science teaching may indeed be our best bet. The battle for a peaceful, non-nuclear world will also require both a greater public understanding of science, and a commitment to work against prejudices induced by religious faith and nationhood. )

  12. Anatomy of an Article: A Film by Sylwester Zabielski and a Case Study by Joseph Janangelo

    ERIC Educational Resources Information Center

    Zabielski, Sylwester; Janagelo, Joseph; Pearson, Jonathan; Hanlon-Baker, Patti; Greer, Jane

    2011-01-01

    This webtext examines the ways that Jonathan Pearson, a recent graduate of The University of Missouri-Kansas City, revised one of his essays to turn it from a seminar paper into a published scholarly article. The project covers a time period from 2004 to 2010 and documents the article's most important streams of input. Those streams include the…

  13. Avoiding the Hazards of Educators--A Response to Joseph Agassi.

    ERIC Educational Resources Information Center

    Sassower, Raphael

    1985-01-01

    Questions of originality and applicability do not detract from Agassi's pedagogical ideas. If there is anything educators can contribute to society, it is to help develop young critical minds that will challenge dogmas so as to find improved ones. (MT)

  14. 78 FR 50098 - Notice of Inventory Completion: St. Joseph County Sheriff's Department, Centreville, MI

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-16

    ... detailed assessment of the human remains was made by the Michigan State University Forensic Anthropology... were transferred to the Michigan State University Forensic Anthropology Department where they were... American based on evaluation by the Michigan State University Forensic Anthropology Department. Pursuant...

  15. A new understanding of the first electromagnetic machine: Joseph Henry's vibrating motor

    NASA Astrophysics Data System (ADS)

    Littman, Michael G.; Stern, Lucas E.

    2011-02-01

    In 1831, Henry invented a battery-powered rocking-beam motor that he later described as the first electromagnetic machine. He repeatedly modified the design over his career, but only one version of a motor actually constructed by Henry is known to exist. This version is in a collection of Henry instruments at Princeton University. We found that the Princeton motor cannot have operated in the form that was displayed as early as 1884. We found evidence in several historical documents and in the instrument itself that the field magnet shown with the motor is a mistake. Instead of a single horizontal bar magnet, the motor was designed to use two elliptical magnets. We presume the error was made by whoever assembled the first public display. We modeled the dynamics of Henry's vibrating motor and compared our results to the operation of a replica motor. Modeling provides insight into how the motor is able to vibrate indefinitely even in the presence of energy loss due to friction.

  16. Assessing Conservation Effects on Water Quality in the St. Joseph River Watershed

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Agriculture is a major contributor to non-point source pollution of streams, rivers and lakes in the United States. In particular, pesticides applied for agricultural crop production can move off-site in runoff and drainage waters, and reach surface drinking water sources. In the northeastern part...

  17. Herbicide Losses in the Saint Joseph River Watershed: Impacts of Hydrology and Land Management

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Herbicide losses from row crop agriculture represent potential human health hazards, and are a major focus of the Conservation Effects Assessment Project (CEAP). Atrazine, simazine, alachlor, acetochlor, metolachlor, and glyphosate were monitored in tile-fed drainage ditches draining to a drinking ...

  18. Joseph Conrad's Empathy for Exploited Africans in "The Heart of Darkness."

    ERIC Educational Resources Information Center

    Farley, Ena L.

    1990-01-01

    Seemingly contradictory positions of J. Conrad as both a racist and an opponent of race-based imperial practices are discussed with reference to "The Heart of Darkness." It is argued that Conrad made a conscious effort to shake off the racial theories of the time and to deplore imperial racism. (SLD)

  19. 77 FR 14441 - Facility Operating License Amendment From Southern Nuclear Operating, Inc., Joseph M. Farley...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-09

    ... entities participating under 10 CFR 2.315(c), must be filed in accordance with the NRC E-Filing rule (72 FR... System (ADAMS): You may access publicly available documents online in the NRC Library at http://www.nrc...) purification system may be connected to the RWST's seismic piping by manual operation of a RWST...

  20. 76 FR 71374 - Joseph Giacchino, M.D.; Decision and Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-17

    ...); Agostino Carlucci, M.D., 49 FR 33,184, 33,184-85 (1984). Rather, what matters--as DEA has repeatedly held... does business. See Scott Sandarg, DMD, 74 FR 17528 (DEA 2009); David W. Wang, M.D., 72 FR 54297 (DEA 2007); Sheran Arden Yeates, M.D., 71 FR 39130 (DEA 2006); Dominick A. Ricci, M.D., 58 FR 51104...

  1. Food for thought: what Jim Joseph taught me about aging and nutrition

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Motor and cognitive behavioral deficits occur in senescence, and in cases of severe deficits, hospitalization and/or custodial care would be a likely outcome. Unless some way is found to reduce these age-related decrements in neuronal function, health care costs will continue to rise exponentially. ...

  2. Joseph A. Burton Forum Award: How to have fun, defend science, and keep up your research

    NASA Astrophysics Data System (ADS)

    Melott, Adrian L.

    2002-04-01

    I will discuss some of the things I've learned about how to effectively combat antiscience activity at the local and regional level. It can be done without excessive drain on one's energy if the focus is on enjoyable, effective activities. Increased effectiveness can come from joining forces with people outside physics who have different skills and different perspectives. I will turn to some of the recently evolved variants of creationism, such as Intelligent Design, which has again confused the issues and made inroads into new US social groups that do not fit the "Monkey Trial" stereotype. I will briefly discuss "fine tuning" arguments in physical cosmology that may be used by ID creationists.

  3. Confluence: Synthesizing the Insights of Joseph Chilton Pearce and Natural Learning Rhythms.

    ERIC Educational Resources Information Center

    Luvmour, Josette; Luvmour, Ba

    1999-01-01

    A theory of childhood development posits an unseen pattern that contains the laws and principles determining the child's nature. An environment that provides attunement to this pattern allows the child profound spiritual awareness, within the limits of the developmental moment. Four stages of development are presented with their attributes,…

  4. Lalande, Joseph-Jérôme Lefrançais de (1732-1807)

    NASA Astrophysics Data System (ADS)

    Murdin, P.

    2000-11-01

    Astronomer, born in Bourg-en-Bresse, France. In what was one of the first internationally coordinated scientific campaigns, to determine the Moon's parallax, he was sent in 1752 to Berlin by the French Académie des Sciences. Other astronomers took up positions at six other sites located on more or less the same meridian from Stockholm to the Cape (where Lalande's colleague LACAILLE was located). ...

  5. 78 FR 73749 - Proposed Amendment of Class D Airspace; St. Joseph, MO

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-09

    ...'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant... read as follows: ] Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR... TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 Proposed Amendment of Class D Airspace; St....

  6. Bringing Religious Traditions into Educational Theory: Making an Example of Joseph Smith, Jr.

    ERIC Educational Resources Information Center

    Warnick, Bryan R.

    2004-01-01

    Educational theorists should engage more deeply with normative religious traditions because people often consult their traditions for guidance about education. Projects that work within such traditions, however, often seem irrelevant or irrational to those on the outside. In contrast, I argue that there are at least three intellectually…

  7. Nerve-responsive troponin I slow promoter does not respond to unloading

    NASA Technical Reports Server (NTRS)

    Criswell, D. S.; Hodgson, V. R.; Hardeman, E. C.; Booth, F. W.

    1998-01-01

    We examined the regulation of the troponin I slow (TnIs) promoter during skeletal muscle unloading-induced protein isoform transition, by using a transgenic mouse line harboring the -4,200 to +12 base pairs region of the human TnIs promoter. Eighteen female transgenic mice ( approximately 30 g body mass) were randomly divided into two groups: weight-bearing (WB) controls (n = 9) and hindlimb unloaded (HU; n = 9). The HU mice were tail suspended for 7 days. Body mass was unchanged in the WB group but was reduced (-6%; P < 0.05) after the HU treatment. Absolute soleus muscle mass (-25%) and soleus mass relative to body mass (-16%) were both lower (P < 0.05) in the HU group compared with the WB mice. Northern blot analyses indicate that 7 days of HU result in a 64% decrease (P < 0.05) in the abundance of endogenous TnIs mRNA (microg/mg muscle) in the mouse soleus. Furthermore, there is a trend for the abundance of the fast troponin I mRNA to be increased (+34%). Analysis of transgenic chloramphenicol acetyltransferase activity in the soleus muscle revealed no difference (P > 0.05) between WB and HU groups. We conclude that additional elements are necessary for the TnIs gene to respond to an unloading-induced, slow-to-fast isoform transition stimulus.

  8. GENERAL VIEW OF MAIN STREET (HIGHWAY 82), LOOKING NORTH, WITH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    GENERAL VIEW OF MAIN STREET (HIGHWAY 82), LOOKING NORTH, WITH THE FIRST BANK OF JOSEPH IN THE FOREGROUND, RIGHT OF CENTER. - Joseph Main Street, Between Joseph & Second Avenues, Joseph, Wallowa County, OR

  9. TOPOGRAPHIC VIEW OF MAIN STREET LOOKING NORTHEAST, WITH THE FIRST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    TOPOGRAPHIC VIEW OF MAIN STREET LOOKING NORTHEAST, WITH THE FIRST BANK OF JOSEPH IN THE FOREGROUND, AND THE SCHLUER BUILDING NEAR THE CENTER OF FRAME. - Joseph Main Street, Between Joseph & Second Avenues, Joseph, Wallowa County, OR

  10. Commentary. Ten Reviews by Patricia D. Mail, Fred Beauvais, James W. Thompson, Joseph Westermeyer, William Sack, Christina M. Mitchell, Fay Cohen, Robert F. Kraus and Thomas Miller, Joseph E. Trimble, and Norman Dinges.

    ERIC Educational Resources Information Center

    Mail, Patricia D.; And Others

    1996-01-01

    Commentaries from 10 researchers concerning "Alcohol Abuse in Urban Indian Adolescents and Women: A Longitudinal Study for Assessment and Risk Evaluation" (R. Dale Walker and others). Reviewers commend the project for adding to the sparse longitudinal research on Indian peoples, while also pointing out problems and issues specific to research on…

  11. Assessment of NEXRAD and Rain Gauge Precipitation Data for Hydrological Response Predictions in the St Joseph River Watershed, USA

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Precipitation is a major driving force variable behind all hydrologic processes needed for watershed modeling studies. The use of point-scale rain gauge data in watershed hydrologic models may not effectively capture the spatial distribution of rainfall; thereby, directly affecting the water balance...

  12. Continual Evaluation of Ditch Sediment and Phosphorus Dynamics in tile fed Drainage Ditches in the St. Joseph Watershed

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Persistent phosphorus (P) amendments to agricultural land continue to be the leading cause of eutrophication and surface water degradation. Therefore, understanding P transport and interaction with agricultural drainage ditch sediments is vital for the development of effective predictive models and ...

  13. Assessment of NEXRAD and Rain Gauge Precipitation Data for Hydrological Response Predictions in the St Joseph River Watershed, USA

    NASA Astrophysics Data System (ADS)

    Heathman, G.; Larose, M.; Huang, C.

    2009-04-01

    Precipitation is a major driving force variable behind all hydrologic processes needed for watershed modeling studies. The use of point-scale rain gauge data in watershed hydrologic models may not effectively capture the spatial distribution of rainfall; thereby, directly affecting the water balance and introducing large uncertainty in the modeling outcome. Rain gauges typically measure the depth of precipitation within a 100 cm2 sampling area (i.e., tipping bucket). Although they usually provide high quality data, a dense rain gauge network must be established to capture the spatial variability of precipitation in an area. Spatially distributed precipitation, such as radar precipitation products from the Next Generation Weather Radar (NEXRAD) of the U.S. National Weather Service, should provide better estimates of the rainfall distribution over large watershed areas. However, NEXRAD estimates may introduce errors due to drop size distributions of rainfall and properties inherent in the radar measurement system. Consequently, there is a need to evaluate NEXRAD Stage III precipitation data against rain gauge precipitation data that are not included in the processing algorithm, as they become available before being used in hydrologic studies. Thus, the objective of this study was to examine the possible sources of error in the Stage III product through radar-gauge intercomparisons using a 3-yr record (2005-2007) of precipitation data from the Agricultural Research Service, National Soil Erosion Laboratory in northeastern Indiana, USA. The results show that the Stage III system estimated an average of 1035.5 mm of precipitation over the rain gauge network area while rain gauges recorded an average of 955.1 mm. The differences in total precipitation depth and percent bias between the Stage III and rain gauge data were 80.4 mm and 8.4 percent, respectively. Stage III overestimation was observed at four out the five rain gauges. Modeling results of watershed hydrologic response using NEXRAD and/or rain gauge precipitation data as input are provided.

  14. Expanding Concepts in Mental Retardation; Scientific Symposium of the Joseph P. Kennedy, Jr., Foundation (3rd, Boston, Massachusetts, 1966).

    ERIC Educational Resources Information Center

    Jervis, George A., Ed.

    The genetics of mental retardation are discussed in terms of geographical isolates, prospects for prevention of trisomic conditions, population genetics, and cytogenetics of Down's syndrome; problems of neurogenesis described are anabolic pathways of galactose and glucose metabolism, abnormal cell migrations in developing brains, and genetic…

  15. The Joseph Priestley Science Center, A Feasibility Study of a Proposed Supplementary Science Center for the Lower Delaware Valley.

    ERIC Educational Resources Information Center

    Cox, Donald W.

    Public school science instruction, research in science curriculum development, and inservice training for science teachers is planned for one central facility. Concentrated natural science courses using science equipment not ordinarily available in schools will be offered to all pupils, 4th through 12th grade, of Philadelphia area school systems.…

  16. Providing Worker Education and Building the Labor Movement: The Joseph S. Murphy Institute of City University of New York

    ERIC Educational Resources Information Center

    D'Amico, Deborah

    2011-01-01

    To provide equitable access to formal, nonformal and workplace learning, experts urge community, business, education and government partnerships. While membership in unions continues to decline and "opportunities for entry-level workers to become skilled workers is lessening," the partnership described in this article shows that it is possible to…

  17. Tropic Trappings in Mel Gibson's "Apocalypto" and Joseph Nicolar's "The Life and Traditions of the Red Man"

    ERIC Educational Resources Information Center

    Kolodny, Annette

    2008-01-01

    With its roots in ancient rhetoric and medieval liturgy, the term "trope" now refers to a figure of speech that organizes a set of complex ideas into a kind of linguistic shorthand. A trope is thus a phrase or image that conveys more than its literal meaning. In this article, two tropes are pertinent: the "pastoral" and the "fortunate fall." The…

  18. A Historical Survey of the Contributions of Francois-Joseph Servois to the Development of the Rigorous Calculus

    ERIC Educational Resources Information Center

    Petrilli, Salvatore John, Jr.

    2009-01-01

    Historians of mathematics considered the nineteenth century to be the Golden Age of mathematics. During this time period many areas of mathematics, such as algebra and geometry, were being placed on rigorous foundations. Another area of mathematics which experienced fundamental change was analysis. The drive for rigor in calculus began in 1797…

  19. "Pedagogy, Identity and the Construction of a Theory of Symbolic Control": Basil Bernstein Questioned by Joseph Solomon.

    ERIC Educational Resources Information Center

    Bernstein, Basil; Solomon, Joseph

    1999-01-01

    Provides background information on Basil Bernstein and his theory of symbolic control and cultural production. Presents an interview with Bernstein addressing such topics as the concept of "pedagogy" and its role in his theory, "boundaries" as a conceptual key in his theory, and transformation of his theory. (CMK)

  20. Public health assessment for Sturgis Municipal Wells, Sturgis, St. Joseph County, Michigan, Region 5. CERCLIS No. MID980703011. Final report

    SciTech Connect

    Not Available

    1993-11-01

    The Sturgis Municipal Wells site was listed on the U.S. Environmental Protection Agency (U.S. EPA) National Priorities List (NPL) in September 1984. In 1982, two of the four wells supplying the City of Sturgis municipal water system were found to be contaminated with trichloroethylene (TCE). Traces of TCE were also found in food products prepared in a plant whose wells were contaminated. Tetrachloroethylene (also called perchloroethylene or PCE) also was found in the original contaminated municipal wells. The contamination in the groundwater has been linked to two source areas: the site of a former woodworking and furniture manufacturing facility and a manufacturer of automotive electrical equipment. TCE, PCE, and other volatile organic compounds have been found in groundwater from monitoring wells within the city, and in soil and soil gas from the source areas. The site currently poses an indeterminate public health hazard. Although there are no indications that exposure to contaminants is occurring at levels of health concern, there is no information available on air concentrations either in the open or in basements.

  1. Health assessment for Sturgis Municipal Wells, St. Joseph County, Michigan, Region 5. CERCLIS No. MID980703011. Preliminary report

    SciTech Connect

    Not Available

    1989-03-10

    The Sturgis Municipal Wells are listed on the National Priorities List. Routine sampling in June 1982 revealed that two of the four municipal water supply wells serving the City of Sturgis (pop. 10,000) were contaminated with trichloroethylene (TCE) and perchloroethylene (PCE). TCE concentrations ranging from 11-74 ppb were detected in both wells. Twenty-eight water samples were taken from existing wells (monitoring, test and production wells) in fall 1987. An industrial process well at Ross Laboratories contained 219 ppb TCE. Soil gas sampling, also performed in fall 1987, revealed several hot spots throughout the city. The following compounds were detected (maximum concentrations in ng/l): TCE, 47,200; PCE, 290,000; 1,1-dichloroethane, 2,040; 1,2-dichloroethane, 1,092; 1,1,1-trichloroethane, 23,600; and toluene; 3,680. The site is of public health concern because of the risk to human health caused by probable human exposure to hazardous substances at levels that may result in adverse human health effects over time. Human exposure to TCE has and is probably occurring via contaminated ground water, and potentially through surface water, soils, and air.

  2. Joseph F. Keithley Award For Advances in Measurement Science: Resonant Ultrasound Spectroscopy: An Odyssey in Measurement Science

    NASA Astrophysics Data System (ADS)

    Migliori, Albert

    Perhaps the speeds of sound, or, equivalently, the elastic moduli are some of the most fundamental attributes of a solid, connecting to fundamental physics, metallurgy, non-destructive testing, and more. Unlike most of the quantities used to characterize condensed matter, the elastic moduli are fourth-rank tensors containing a wealth of detail, directional information, and consistency constraints that provide some of the most revealing probes of solids. We describe here the current state of the art in one method, Resonant Ultrasound Spectroscopy, where the mechanical resonances of a specimen of regular shape (easy to measure) are analyzed (difficult computational problem) to obtain the full elastic tensor. With modern advances in electronics and analysis, fractions of a part per million changes in elastic moduli are detectable providing new and important insight into grand challenges in condensed matter physics. This work was supported as part of the Materials Science of Actinides, an Energy Frontier Research Center funded by the U.S. Department of Energy, Office of Science, Basic Energy Sciences under Award # DE-SC0001089.

  3. Arsenic and Old Mustard: Chemical Problems of Old Arsenical and 'Mustard' Munitions (Joseph F. Bunnett and Marian Mikotajczyk, Eds.)

    NASA Astrophysics Data System (ADS)

    Garrett, Benjamin

    1999-10-01

    What do Knute Rockne, Notre Dame's famed football coach, and Lewisite, a chemical warfare agent dubbed "the dew of death", have in common? Both owe their discovery to Father Julius Arthur Nieuwland.1 Rockne's legacy lives on in the Fighting Irish and their tradition of excellence on the gridiron. Lewisite, together with other arsenical- and mustard-type chemical warfare agents, provide a legacy that lives on, too, but with less cheerful consequences. The book Arsenic and Old Mustard: Chemical Problems of Old Arsenical and 'Mustard' Munitions makes clear the challenges faced in dealing with those consequences. This book documents the proceedings of a workshop devoted to arsenical- and mustard-type chemical warfare agents and their associated munitions. The workshop, held in Poland in 1996, included nine lectures, eight posters, and three discussion groups; and the contents of all these are presented. Major support for the workshop came from the Scientific Affairs Division of NATO as part of on ongoing series of meetings, cooperative research projects, and related efforts dealing with problems leftover from the Cold War and, in the case of the arsenicals and mustards, from conflicts dating to World War I. These problems can be seen in contemporary accounts, including a January 1999 news report that the U.S. Department of Defense intends to survey Washington, DC, areas near both American University and the Catholic University of America (CUA), site of the original synthesis of Lewisite, for chemical warfare agents and other materials disposed at the end of World War I.2 The first nine chapters of the book present the workshop's lectures. Of these, readers interested in chemical weapon destruction might find especially useful the first chapter, in which Ron Mansley of the Organisation for the Prohibition of Chemical Weapons presents a scholarly overview covering historical aspects of the arsenicals and mustards; their production and use; prospective destruction technologies; and international obligations attendant to the Chemical Weapons Convention, which entered into force in 1997. Hermann Martens's presentation of German arsenical and mustard munitions and of technical approaches to their destruction is similarly detailed, thorough, and engaging. W. R. Cullen's chapter "Arsenic in the Environment" and Shigeru Maeda's chapter "Biotransformation of Arsenic in Freshwater Organisms" help place the problems associated with the arsenicals in their environmental context and, hence, should appeal to a large audiencenot merely those specialists dealing with chemical weapon destruction. The reports of the three discussion groupsYperite,3 Arsenicals, and Recovered Munitionsprovide useful summaries of current knowledge and needs for additional research. The Arsenicals report observes that "destruction of arsenical agents appears to have received little attention." This situation may change if searches in Washington, DC, should uncover caches of old arsenicals at CUA and, especially, when the governments of the People's Republic of China and Japan agree on funding for destruction of the chemical munitions Japan caused to be abandoned on what is now the territory of the PRC. A conservative estimate is that there are 2,000,000 of these abandoned munitions, most of them being arsenicals and mustards.4 Notes and References 1. Nieuwland (1878-1936) hired Rockne in 1914 as a chemistry instructor. According to Father Nieuwland, Rockne owed much of his prowess as one of the greatest coaches of all time to his training in chemistry, which taught him the method of reasoning (Ind. Eng. Chem. New Ed., April 20, 1931). W. Lee Lewis, Lewisite's eponym, credits Nieuwland's unpublished dissertation as the source for his 1918 synthesis (Lewis, W. L.; Perkins, G. A. The beta-Chlorovinyl Chloroarsines; Ind. Eng. Chem. 1923, 15, 290-295). Lewisite itself is actually the group of mono-, di-, and tri-substituted 2-chloroethenyl derivatives of arsenic(III) chloride. 2. Vogel, S. Search to Resume near AU for WWI Chemica

  4. MOOCs and Joseph Lancaster: Lessons from a Two-Hundred Year Precedent in Mass Learning on a Global Scale

    ERIC Educational Resources Information Center

    Stevenson, William R., III

    2015-01-01

    Over the past three years, Massive Open Online Courses, or MOOCs, have spanned the globe, educating millions with the potential to reach millions more. Taught by leading academics from top institutions, the courses are as complete as those offered in traditional settings; yet, in being web-based and tuition free, they disregard long-standing…

  5. Experiments in Physical Chemistry, Sixth Edition (by David P. Shoemaker, Carl W. Garland, and Joseph W. Nibler)

    NASA Astrophysics Data System (ADS)

    Feigerle, Charles S.

    1997-05-01

    McGraw-Hill: New York, 1996. xii + 778 pp. ISBN 0-07-057074-4. Experiments in Physical Chemistry has long been one of the best textbooks available for undergraduate courses in physical chemistry laboratory. The present edition follows a similar format as previous editions, consisting of (i) a series of introductory sections dealing with common aspects of all experiments, such as recording of data, report writing, data and error analysis, and the use of computer software to aide in these, (ii) 48 experiments spanning 12 fundamental areas, and (iii) a series of resource chapters providing an introduction to electronics, instruments, techniques, and procedures commonly utilized in the performance of experiments in physical chemistry. Some needed changes have been incorporated in this edition, most notably the addition of sections that recognize the increased role of computers in modern experimentation. In particular, the section on computer software has been expanded and moved ahead of the experiments. The use of word processing, spreadsheets, and symbolic mathematics programs is emphasized, with examples using some of the most popular commercial programs. Three new experiments have been added and a fourth substantially modified. Each of the 44 other experiments has undergone some review and modernization, and a much-needed section on safety issues has been added to each. A resource chapter on computer interfacing, treating data types, programming languages and interfacing has been added. Examples are given for programming RS-232 communication and analog/digital interface boards using visual basic routines. I recommend this book be given serious consideration as a text for a one- or two-semester course in physical chemistry laboratory. The approach to experimentation in physical chemistry, the experiments, and the techniques that are described can form a solid basis for such a course. My one criticism is that the text offers only a limited number of laser-based experiments. This represents a minor drawback to an overall strong text, since those who wish to emphasize the use of lasers can easily supplement the choice of experiments from the numerous alternatives available in the literature.

  6. Decalepisarayalpathra (J. Joseph & V. Chandras.) Venter, an endemic and endangered ethno medicinal plant from Western Ghats, India.

    PubMed

    Verma, Sunil K; Sarkar, Manoj K

    2015-01-01

    Decalepis arayalpatra is an endemic and critically endangered plant of India. May 2014 issue of Natural Products Research publishes the findings of R. S. Verma et al. on the chemical composition of D. arayalpatra. This study was conducted to characterise the root aroma of this plant for possible industrial applications. The authors suggest that due to its peculiar vanilla flavour, the plant could be explored as a potential substitute of vanillin-aroma in the flavour industry. Owing to the fact that D. arayalpatra is a critically endangered plant species, and its habitat is now limited to only the protected areas and reserve forest in southern part of India, and that collecting any plant from such reserve forests for commercial activities is illegal as per the law of the country, this specific conclusion of the authors is totally un-substantiated by the law of land, hence, calls for further review. PMID:25133451

  7. Research highlights for the period February 1, 1980-July 31, 1980. [Joseph Henry Labs. , Dept. of Physics, Princeton Univ

    SciTech Connect

    Shoemaker, F C

    1980-08-01

    Very brief summaries of research during the period February 1, 1980 to July 31, 1980 are given. The subjects included muon interactions, charmed particles, muon pair production, and the eta/sub c/ meson. Completed work has been published. (RWR)

  8. Scanning Cargo Containers with Tagged Neutrons

    NASA Astrophysics Data System (ADS)

    Viesti, G.; Botosso, C.; Fabris, D.; Lunardon, M.; Moretto, S.; Nebbia, G.; Pesente, S.; Zenoni, A.; Donzella, A.; Perot, B.; Carasco, C.; Bernard, S.; Mariani, A.; Szabo, J.-L.; Sannie, G.; Valkovic, V.; Sudac, D.; Nad, K.; Peerani, P.; Sequeira, V.; Salvato, M.; Moszynski, M.; Gierlik, M.; Klamra, W.; Le Tourneur, P.; Lhuissier, M.; Colonna, A.; Tintori, C.

    2007-10-01

    A new Tagged Neutron Inspection System (TNIS) able to detect illicit materials such as explosives and narcotics in cargo containers has been developed within the EURopean Illicit TRAfficing Countermeasures Kit (EURITRACK) project. After the R&D phase, the inspection portal has been installed and commissioned at the Rijeka seaport in Croatia, where it has been operated in connection with the existing X-ray scanner for a first two-month demonstration campaign. Results obtained are presented and discussed in this paper.

  9. Scanning Cargo Containers with Tagged Neutrons

    SciTech Connect

    Viesti, G.; Botosso, C.; Fabris, D.; Lunardon, M.; Moretto, S.; Nebbia, G.; Pesente, S.; Zenoni, A.; Donzella, A.; Perot, B.; Carasco, C.; Bernard, S.; Mariani, A.; Szabo, J.-L.; Sannie, G.; Valkovic, V.; Sudac, D.; Nad, K.; Peerani, P.; Sequeira, V.

    2007-10-26

    A new Tagged Neutron Inspection System (TNIS) able to detect illicit materials such as explosives and narcotics in cargo containers has been developed within the EURopean Illicit TRAfficing Countermeasures Kit (EURITRACK) project. After the R and D phase, the inspection portal has been installed and commissioned at the Rijeka seaport in Croatia, where it has been operated in connection with the existing X-ray scanner for a first two-month demonstration campaign. Results obtained are presented and discussed in this paper.

  10. ELEVATION VIEW OF THE BARNARD BUILDING AND FIRST NATIONAL BANK ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    ELEVATION VIEW OF THE BARNARD BUILDING AND FIRST NATIONAL BANK BUILDING, LOCATED AT 012-014 MAIN STREET, VIEW LOOKING EAST. - Joseph Main Street, Between Joseph & Second Avenues, Joseph, Wallowa County, OR

  11. To designate the United States courthouse located at 700 Grant Street in Pittsburgh, Pennsylvania, as the "Joseph F. Weis Jr. United States Courthouse".

    THOMAS, 113th Congress

    Rep. Doyle, Michael F. [D-PA-14

    2014-07-17

    12/09/2014 Received in the Senate and Read twice and referred to the Committee on Environment and Public Works. (All Actions) Tracker: This bill has the status Passed HouseHere are the steps for Status of Legislation:

  12. Joseph A. Burton Forum Award Talk: How a Physics Education has Influenced Practice and Graduate Education in Technically-Focused Quantitative Policy Analysis

    NASA Astrophysics Data System (ADS)

    Granger Morgan, M.

    2011-04-01

    In a book for the general public published a year before his death, Carl Sagan wrote, "Every time a scientific paper presents a bit of data, it's accompanied by an error bar---a quiet but instant reminder that no knowledge is complete or perfect." For those of us educated in experimental natural science such an observation seems so obvious as to hardly need saying. Yet when, after completing a PhD in experimental radio physics, I began to work on problems in environmental and energy risk and policy analysis in the early 1970s, I was amazed to find that the characterization and treatment of uncertainty was almost completely lacking in the analysis of that day. In the first part of this talk, I will briefly summarize how I, and a number of my physics-educated colleagues, have worked to rectify this situation. Doctoral education in the Department of Engineering and Public Policy (EPP) at Carnegie Mellon University has also been shaped by a number of ideas and problem-solving styles that derive from physics. These have been strengthened considerably through integration with a number of ideas from experimental social science -- a field that too many in physics ignore or even belittle. In the second part of the talk, I will describe the PhD program in EPP, talk a bit about some of its unique features, and describe a few of the problems we address.

  13. Chief Joseph Kokanee Enhancement Project; Characterization of Pump Flow at the Grand Coulee Dam Pumping Station for Fish Passage, 2004-2005 Final Report.

    SciTech Connect

    Carlson, T.; Duncan, J.; Johnson, R.

    2005-03-01

    This report describes a study conducted by Pacific Northwest National Laboratory (PNNL) for the Bonneville Power Administration to characterize the conditions fish experience when entrained in pump flow at the Grand Coulee Dam. PNNL conducted field studies at Grand Coulee Dam in 2004 using the Sensor Fish to measure the acceleration and pressure conditions that might be experienced by fish that pass through pumps at Grand Coulee Dam's Pump-Generating Plant and are transported up into the feeder canal leading to Banks Lake. The probability that fish would be struck by the Pump-Generating Plant's new nine-bladed turbines was also estimated. Our measurements showed relatively low turbulence except in the immediate vicinity of the runner environment. The lowest and highest pressures experienced by the Sensor Fish were 6.4 and 155 psi (the pressure gauge saturated at 155 psi). The probability of strike was also calculated, based on the average length of hatchery-reared juvenile kokanee (land-locked sockeye). Strike probabilities ranged from 0.0755 for 2.36-inch fish to 0.3890 for 11.8-inch fish. The probability of strike estimates indicate that the majority (77%) of recently released hatchery kokanee would be carried through the test pump without being struck and most likely with low risk of injury resulting from pressure and turbulence exposure. Of the 23% that might be struck it is expected that 60% would arrive in Banks Lake without visible external injuries. Thus more than 90% of entrained fish could be expected to arrive in Banks Lake without significant injury, assuming that no kokanee were injured or killed by pressure exposure during passage.

  14. A resolution to authorize representation by the Senate Legal Counsel in the case of Common Cause, et al. v. Joseph R. Biden, et al.

    THOMAS, 112th Congress

    Sen. Reid, Harry [D-NV

    2012-06-06

    06/06/2012 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S3799; text as passed Senate: CR S3799; text of measure as introduced: CR S3783) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  15. Timeless and Timely Advice: A Commentary on "Consultation to Facilitate Planned Organizational Change in Schools," an Article by Joseph E. Zins and Robert J. Illback

    ERIC Educational Resources Information Center

    Hazel, Cynthia E.

    2007-01-01

    This commentary on Zins and Illback's (1995) article, Consultation to Facilitate Planned Organizational Change in Schools, argues that the authors provided a solid foundation for well-planned, proactive, sustainable, internally-driven systemic change in schools that has yet to be widely realized. Their school organizational change model and more…

  16. Making a Difference in Research and Practice: A Commentary on "Consulting to Facilitate Planned Organizational Change in Schools," an Article by Joseph E. Zins and Robert J. Illback

    ERIC Educational Resources Information Center

    Flaspohler, Paul D.

    2007-01-01

    Zins and Illback observed in 1995 that planned organizational change processes were neglected in practice, training, and research. In the decade following publication of their article, implementation of processes and structures of planned organizational change increased dramatically. Schools and school districts continue to face increased…

  17. Jay L. King, Joseph D. Huxman, and Orion D. Billeter Assist Pilot Milt Thompson into the M2-F2 Attac

    NASA Technical Reports Server (NTRS)

    1966-01-01

    NASA research pilot Milt Thompson is helped into the cockpit of the M2-F2 lifting body research aircraft at NASA's Flight Research Center (now the Dryden Flight Research Center). The M2-F2 is attached to a wing pylon under the wing of NASA's B-52 mothership. The flight was a captive flight with the pilot on-board. Milt Thompson flew in the lifting body throughout the flight, but it was never dropped from the mothership. NASA B-52, Tail Number 008, is an air launch carrier aircraft, 'mothership,' as well as a research aircraft platform that has been used on a variety of research projects. The aircraft, a 'B' model built in 1952 and first flown on June 11, 1955, is the oldest B-52 in flying status and has been used on some of the most significant research projects in aerospace history. Some of the significant projects supported by B-52 008 include the X-15, the lifting bodies, HiMAT (highly maneuverable aircraft technology), Pegasus, validation of parachute systems developed for the space shuttle program (solid-rocket-booster recovery system and the orbiter drag chute system), and the X-38. The B-52 served as the launch vehicle on 106 X-15 flights and flew a total of 159 captive-carry and launch missions in support of that program from June 1959 to October 1968. Information gained from the highly successful X-15 program contributed to the Mercury, Gemini, and Apollo human spaceflight programs as well as space shuttle development. Between 1966 and 1975, the B-52 served as the launch aircraft for 127 of the 144 wingless lifting body flights. In the 1970s and 1980s, the B-52 was the launch aircraft for several aircraft at what is now the Dryden Flight Research Center, Edwards, California, to study spin-stall, high-angle-of attack, and maneuvering characteristics. These included the 3/8-scale F-15/spin research vehicle (SRV), the HiMAT (Highly Maneuverable Aircraft Technology) research vehicle, and the DAST (drones for aerodynamic and structural testing). The aircraft supported the development of parachute recovery systems used to recover the space shuttle solid rocket booster casings. It also supported eight orbiter (space shuttle) drag chute tests in 1990. In addition, the B-52 served as the air launch platform for the first six Pegasus space boosters. During its many years of service, the B-52 has undergone several modifications. The first major modification was made by North American Aviation (now part of Boeing) in support of the X-15 program. This involved creating a launch-panel-operator station for monitoring the status of the test vehicle being carried, cutting a large notch in the right inboard wing flap to accommodate the vertical tail of the X-15 aircraft, and installing a wing pylon that enables the B-52 to carry research vehicles and test articles to be air-launched/dropped. Located on the right wing, between the inboard engine pylon and the fuselage, this wing pylon was subjected to extensive testing prior to its use. For each test vehicle the B-52 carried, minor changes were made to the launch-panel operator's station. Built originally by the Boeing Company, the NASA B-52 is powered by eight Pratt & Whitney J57-19 turbojet engines, each of which produce 12,000 pounds of thrust. The aircraft's normal launch speed has been Mach 0.8 (about 530 miles per hour) and its normal drop altitude has been 40,000 to 45,000 feet.. It is 156 feet long and has a wing span of 185 feet. The heaviest load it has carried was the No. 2 X-15 aircraft at 53,100 pounds. Project manager for the aircraft is Roy Bryant.

  18. Troubles de l'hémostase en réanimation chirurgicale de l'Hôpital Universitaire Joseph Ravoahangy Andrianavalona Antananarivo

    PubMed Central

    Rasoamampianina, Lalaina Elianah; Rafanomezantsoa, Toky Andriamahefa; Rakotondrainibe, Aurélia; Rajaonera, Andriambelo Tovohery; Randriamanantany, Zely Arivelo; Alson, Olivat Rakoto; Raveloson, Nasolotsiry Enintsoa

    2015-01-01

    Les troubles de l'hémostase sont fréquemment observés en réanimation. L'objectif de cette étude est d'en déterminer l'incidence, les étiologies et la prise en charge pour en diminuer le risque de morbi-mortalité. Etude rétrospective sur une période de huit mois en réanimation chirurgicale du CHUA HUJRA. Les dossiers étudiés étaient ceux contenant tous les premiers bilans d'hémostase lors de l'admission du patient en réanimation, avec un âge supérieur à 15 ans. Etaient exclus les dossiers des post opérés (malade ayant subi une intervention chirurgicale). Les dossiers retenus pour l'étude étaient ceux qui ont présenté une ou plusieurs anomalies au niveau du bilan d'hémostase. Cent cinquante-cinq dossiers ont été colligés dont 20,64% ont présenté un trouble de l'hémostase. Les patients de sexe féminin (53,12%) étaient les plus concernés, avec une population âgée en moyenne de 49±19 ans. Trois patients (9,37%) ont présenté une notion de diathèse hémorragique à l'interrogatoire. Les différents troubles de l'hémostase étaient: une diminution du taux de prothrombine (100%), un taux de céphaline activé allongé (78,12%), un international normalized ratio élevé (43,75%) et des thrombopénies (40,62%). Chez 3,12% de ces cas, des accidents hémorragiques ont survenu. La plupart de ces troubles de l'hémostase étaient présents au décours d'hémorragies digestives (46,87%) dont la prise en charge était constituée par l'administration de vitamine K1 (68,75%) et de transfusion de plasma frais congelé (65,62%). D'autres pathologies ont été également incriminées. Une incidence de 15,62% de mortalité a été retrouvée. L'existence des troubles de l'hémostase en réanimation constitue un facteur pronostique imposant un dépistage et une prise en charge précoces et adéquats pour pouvoir en réduire le taux de mortalité. PMID:26848361

  19. What if Educational Inquiry Were Neither a Social Science nor a Humanities Field? Revisiting Joseph Schawb's "The Practical" in the Aftermath of the Science Wars

    ERIC Educational Resources Information Center

    Donmoyer, Robert

    2014-01-01

    The recent debates about what constitutes scientific research in Education, on the one hand, and the so-called "paradigm wars" that got played out in the final quarter of the 20th century, on the other, are more similar than different. At the center of both controversies was the relative worth of quantitative and qualitative research…

  20. Application of the Soil and Water Assessment Tool and Annualized Agricultural Non-Point Source Models in the St. Joseph River Watershed

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This study evaluated the performance of two water quality models in accordance to specific tasks designated in the USDA Agricultural Research Service Conservation Effects Assessment Project. The Soil and Water Assessment Tool (SWAT) and the Annualized Agricultural Non-Point Source (AnnAGNPS) models ...

  1. Sir Francis Joseph Campbell and His Family: The First Family in Professional Services for People Who Are Blind or Visually Impaired

    ERIC Educational Resources Information Center

    Welsh, Richard L.

    2008-01-01

    The author discusses the pivotal roles of Sir Francis Campbell (1832-1914) and members of his family, especially his son Charles Campbell, in the evolution of the blindness field to a professional and reason-based service.

  2. A Faraday Rotation Investigation to Probe the Shells of HII Regions with Associated Stellar Bubbles%A Costa, Allison H.; Spangler, Steven R.; Sink, Joseph R.

    NASA Astrophysics Data System (ADS)

    Costa, Allison H.; Spangler, Steven R.; Sink, Joseph R.

    2015-01-01

    We performed polarimetric observations with the Very Large Array of 11 extra-galactic radio sources with lines of sight through the shell of the Rosette Nebula (VLA project AS1110). This investigation supplements the study of the shell of the Rosette Nebula by Savage et al. (2013). We utilize two methods for calculating the rotation measure (RM) for the new lines of sight. The first is using the traditional method of least-squares fit to χ(λ2), and the second is using RM Synthesis (Brentjens & Bruyn 2005). We present a comparison of the two methods of obtaining RM values, and we find excellent agreement between the two methods. In addition, we discuss a plasma shell model, which is intended to reproduce the sign and magnitude of the observed RM due to the shell, with a new method of determining the model parameters, such as the inner and outer radii and the electron density, for specific lines of sight. This treatment of the model parameters allows us to extend our investigation to HII regions that do not have spherical symmetry, like the Heart Nebula/W4. We describe a new method of fitting a local shell model to specific lines of sight and then calculating the associated RM. By modeling the magnitude of the RM for specific lines of sight, we can better distinguish between a scenario where an observed excess in RM is due to an amplification of the magnetic field or one where it is exclusively due to an increase in the density of the shell. This research was supported at the University of Iowa by grant AST09-07911 and ATM09-56901 from the National Science Foundation.

  3. Population Dynamics and Conservation Implications of Decalepis arayalpathra (J. Joseph and V. Chandras.) Venter., a Steno Endemic Species of Western Ghats, India.

    PubMed

    Mishra, Priyanka; Kumar, L Dinesh; Kumar, Amit; Gokul, Sivaraman; Ravikumar, Kaliamoorthy; Shukla, Ashutosh K; Sundaresan, Velusamy

    2015-07-01

    Decalepis arayalpathra, a critically endangered plant species, has a restricted and fragmented population in Southern Western Ghats, India. This study is a first attempt to evaluate genetic diversity and population structure in the nine wild populations of D. arayalpathra based on molecular pattern realized through the marker assays. Principal coordinate analysis (PCoA) and Nei's unweighted pair-group method with arithmetic average (UPGMA)-based hierarchical clustering of both the marker assays suggest strong genetic clustering between the individuals corresponding to their geographical ranges. Mantel test also corroborates a close genetic proximity between genetic and geographic data (r = 0.389). Population genetic analysis revealed low levels of gene flow [inter-simple sequence repeat (ISSR) = 0.289 and random amplified polymorphic DNA (RAPD) = 0.847] between the populations, in line with high genetic differentiation (Gst = 0.531 with ISSR and 0.440 with RAPD), which was also supported by analysis of molecular variance (AMOVA), that 54 % (ISSR) and 64 % (RAPD) total variation resided within populations. Bayesian model-based STRUCTURE analysis detected three genetic clusters showing the high degree of admixture within population. Based on the findings, such as inbreeding depression and the loss of genetic diversity, suggestions for conservation strategies are provided to preserve the genetic resources of this endangered species. PMID:25969156

  4. Investigation of the radiological safety concerns and medical history of the late Joseph T. Harding, former employee of the Paducah Gaseous Diffusion Plant

    SciTech Connect

    Vallario, E.J.; Wolfe, H.R.

    1981-03-01

    An ex-employee's claims that inadequate enforcement of radiation safety regulations allowed excess radiation exposure thereby causing his deteriorating health was not substantiated by a thorough investigation.

  5. The life of Dr Jan Ingen Housz (1730-99), private counsellor and personal physician to Emperor Joseph II of Austria.

    PubMed

    Housz, Jan Maarten Ingen; Beale, Norman; Beale, Elaine

    2005-02-01

    A brief biography is presented of Dr Jan Ingen Housz, as written, originally in Dutch, by M J Godefroi, a mid-nineteenth-century Dutch physician who was a friend of a near descendant of Dr Ingen Housz. From being a general practitioner at Breda, his home town, he moved to England to learn smallpox inoculation, was sent to inoculate members of the Habsburg family at Vienna and dedicated his later life to scientific experimentation, notably revealing the fundamentals of photosynthesis. PMID:15682228

  6. 33 CFR 334.670 - Gulf of Mexico south and west of Apalachicola, San Blas, and St. Joseph bays; air-to-air firing...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 3 2013-07-01 2013-07-01 false Gulf of Mexico south and west of....670 Section 334.670 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE DANGER ZONE AND RESTRICTED AREA REGULATIONS § 334.670 Gulf of Mexico south and west...

  7. 33 CFR 334.670 - Gulf of Mexico south and west of Apalachicola, San Blas, and St. Joseph bays; air-to-air firing...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 3 2014-07-01 2014-07-01 false Gulf of Mexico south and west of....670 Section 334.670 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE DANGER ZONE AND RESTRICTED AREA REGULATIONS § 334.670 Gulf of Mexico south and west...

  8. 33 CFR 334.670 - Gulf of Mexico south and west of Apalachicola, San Blas, and St. Joseph bays; air-to-air firing...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 3 2012-07-01 2012-07-01 false Gulf of Mexico south and west of....670 Section 334.670 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE DANGER ZONE AND RESTRICTED AREA REGULATIONS § 334.670 Gulf of Mexico south and west...

  9. Comparison of Precipitation data from NEXRAD and ARS-NSERL Rain Gauges for hydrological study in the St. Joseph River Watershed, IN

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Precipitation is a major driving force variable behind all hydrologic processes needed for watershed modeling studies. The use of point-scale rain gauge data in watershed hydrologic models may not effectively capture the spatial distribution of rainfall; thereby, directly affecting the water balance...

  10. The Problems in the Classification of the African Languages; Methodological and Theoretical Conclusions Concerning the Classification System of Joseph H. Greenberg. Studies on Developing Countries No.5.

    ERIC Educational Resources Information Center

    Fodor, Istvan

    The present work deals with Africanistic problems, raising questions of interest for general linguists, and linguists working in Indo-European, Finno-Ugric, and other special branches. The first two chapters deal with the field and difficulties of African studies and the general characterization of the African languages. Following chapters discuss…

  11. Towards a Social History of Technological Ideas: Joseph Black, James Watt, and the Separate Condenser. An Occasional Paper on Man/Society/Technology.

    ERIC Educational Resources Information Center

    Donovan, Arthur

    This seminar paper explores the role that historians of technology can play in the reevaluation of the relationship between technical and social change. Historians of technology need to ask questions about the nontechnological aspects of society which have influenced technical change in the past. In the realm of ideas, historians should check…

  12. Joseph F. Keithley Award For Advances in Measurement Science Lecture: Thermophotonic and Photoacoustic Radar Imaging Methods for Biomedical and Dental Imaging

    NASA Astrophysics Data System (ADS)

    Mandelis, Andreas

    2012-02-01

    In the first part of this presentation I will introduce thermophotonic radar imaging principles and techniques using chirped or binary-phase-coded modulation, methods which can break through the maximum detection depth/depth resolution limitations of conventional photothermal waves. Using matched-filter principles, a methodology enabling parabolic diffusion-wave energy fields to exhibit energy localization akin to propagating hyperbolic wave-fields has been developed. It allows for deconvolution of individual responses of superposed axially discrete sources, opening a new field: depth-resolved thermal coherence tomography. Several examples from dental enamel caries diagnostic imaging to metal subsurface defect thermographic imaging will be discussed. The second part will introduce the field of photoacoustic radar (or sonar) biomedical imaging. I will report the development of a novel biomedical imaging system that utilizes a continuous-wave laser source with a custom intensity modulation pattern, ultrasonic phased array for signal detection and processing coupled with a beamforming algorithm for reconstruction of photoacoustic correlation images. Utilization of specific chirped modulation waveforms (``waveform engineering'') achieves dramatic signal-to-noise-ratio increase and improved axial resolution over pulsed laser photoacoustics. The talk will conclude with aspects of instrumental sensitivity of the PA Radar to optical contrast using cancerous breast tissue-mimicking phantoms, super paramagnetic iron oxide nanoparticles as contrast enhancement agents and in-vivo tissue samples.

  13. 77 FR 54577 - Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-05

    ...: 1. Rebecca Watson Vizard, St. Joseph Louisiana; Michael Rene Vizard, St. Joseph, Louisiana; Sarah..., St. Joseph, Louisiana, (collectively known as the ``Vizard Family Group'') to retain of the shares of, and thereby control of, BSJ Bancshares, Inc., St. Joseph, Louisiana, and indirectly control Cross...

  14. 75 FR 47891 - Notice of Intent to Rule on Request to Release Airport Property at the Dubois Regional Airport...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-09

    ...-aeronautical airport property to Joseph and Rosemary Barber. Also, Joseph and Rosemary Barber desire to... Rosemary Barber. The ROW continues to be needed by Joseph and Rosemary Barber to access SR 830 from their property. Therefore, the Authority desires to convey their half of the former ROW to Joseph and...

  15. Amend the title so as to read: `Condemning Joseph Kony and the Lord's Resistance Army for committing crimes against humanity and mass atrocities, and supporting ongoing efforts by the United States Government and governments and regional organizations in central Africa to remove Joseph Kony and Lord's Resistance Army commanders from the battlefield.'.

    THOMAS, 112th Congress

    Sen. Coons, Christopher A. [D-DE

    2012-03-21

    08/02/2012 Resolution agreed to in Senate with an amendment and an amendment to the Title and an amended preamble by Unanimous Consent. (text: CR S6009-6010) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  16. 2250-MHz High Efficiency Microwave Power Amplifier (HEMPA)

    NASA Technical Reports Server (NTRS)

    Sims, W. Herbert; Bell, Joseph L. (Technical Monitor)

    2001-01-01

    Tnis paper will focus on developing an exotic switching technique that enhances the DC-to-RF conversion efficiency of microwave power amplifiers. For years, switching techniques implemented in the 10 kHz to 30 MHz region have resulted in DC-to-RF conversion efficiencies of 90-95-percent. Currently amplifier conversion efficiency, in the 2-3 GHz region approaches, 10-20-percent. Using a combination of analytical modeling and hardware testing, a High Efficiency Microwave Power Amplifier was built that demonstrated conversion efficiencies four to five times higher than current state of the art.

  17. RDA Requirements For Optimum Hybrid Focal Plane Performance

    NASA Astrophysics Data System (ADS)

    Grossman, S. B.; Emmons, R. B.; Hawkins, S. R.

    1982-06-01

    In analyzing the performance of direct-injected hybrid focal plane arrays, many factors must be consiaered in determining the minimum detector resistance-area product RDA neces-sary to obtain background-limited performance (BLIP) and good array uniformity. In photo-aioue arrays, a necessary but not sufficient condition is that noise due to the diode generation-recombination and diffusion currents are less than the background photon shot noise. Tnis places a minimum requirement on the magnitude of RoA, the zero bias resistance area product. In addition, there are generally much more stringent requirements on RDA uue to input MOSFET l/f noise and threshold variations which exceed the single detector RoA requirement for BLIP operation at a given background. In general, the input thresnolu variations require that the photodiodes be somewhat back-biased. This produces a substantially higner average RDA at the expense of higher detector l/f noise due to surface leakage. In tnis study we have investigated the detector impedance requirements in terms of tne injection efficiency, threshold nonuniformities, the input MOSFET excess (l/f) noise, and tne detector excess noise. For state-of-the-art parameters, it was determined tnat tne input MOSFET l/f noise always dominates the other elements in determining the required detector impeaance:k

  18. 75 FR 3904 - Change in Bank Control Notices; Acquisition of Shares of Bank or Bank Holding Companies

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-25

    ... Denney, Assistant Vice President) 1 Memorial Drive, Kansas City, Missouri 64198-0001: 1. Verlyn Joseph Herman, Jr., and Aaron Joseph Herman, both of Norton, Kansas; as members of a family group acting...

  19. 9. Historic American Buildings Survey Cortlandt V. D. Hubbard, Photographer ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. Historic American Buildings Survey Cortlandt V. D. Hubbard, Photographer July 1966 INTERIOR OF CANDLE FACTORY BEHIND JOSEPH STARBUCK HOUSE - Joseph Starbuck House, 4 New Dollar Lane, Nantucket, Nantucket County, MA

  20. 7. Historic American Buildings Survey Cortlandt V. D. Hubbard, Photographer ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Historic American Buildings Survey Cortlandt V. D. Hubbard, Photographer July 1966 CANDLE FACTORY ON STARBUCK COURT BEHIND JOSEPH STARBUCK HOUSE - Joseph Starbuck House, 4 New Dollar Lane, Nantucket, Nantucket County, MA

  1. 8. Historic American Buildings Survey Cortlandt V. D. Hubbard, Photographer ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Historic American Buildings Survey Cortlandt V. D. Hubbard, Photographer July 1966 CANDLE FACTORY ON STARBUCK COURT BEHIND JOSEPH STARBUCK HOUSE - Joseph Starbuck House, 4 New Dollar Lane, Nantucket, Nantucket County, MA

  2. 78 FR 3498 - Proposed Collection; Comment Request for Form 14417-A

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-16

    ... additional information or copies of the form and instructions should be directed to R. Joseph Durbala, (202... information. Approved: January 9, 2013. R. Joseph Durbala, IRS Reports Clearance Officer. BILLING CODE...

  3. 1. Historic American Buildings Survey E. W. Russell, Photographer, February ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey E. W. Russell, Photographer, February 6, 1936 WROUGHT IRON FENCE AND GATE WITH CAST IRON ORNAMENTS, 251 Saint Joseph Street - 251 Saint Joseph Street (Iron Fence & Gate), Mobile, Mobile County, AL

  4. Thoughts on "Reconsidering the Washington-Du Bois Debate: Two Black Colleges in 1910-1911" and Thoughts on "Liberalism at the Crossroads: Jimmy Carter, Joseph Califano, and Public College Desegregation."

    ERIC Educational Resources Information Center

    Edwards, Anthony

    These two papers offer critiques of two essays that appeared in "Essays in Twentieth-Century Southern Education: Exceptionalism and its Limits," edited by Wayne J. Urban. The first paper examines Linda Buchanan and Philo Hutcheson's interpretation of the debate which underscored the well-known conflict between Booker T. Washington-W.E.B. DuBois…

  5. To designate the facility of the United States Postal Service located at 113 West Jackson Street in Rich Square, North Carolina, as the "Chief Joseph E. White, Jr. Post Office Building".

    THOMAS, 113th Congress

    Rep. Butterfield, G. K. [D-NC-1

    2014-07-17

    11/18/2014 Received in the Senate and Read twice and referred to the Committee on Homeland Security and Governmental Affairs. (All Actions) Tracker: This bill has the status Passed HouseHere are the steps for Status of Legislation:

  6. S.Res.485 — 112th Congress (2011-2012) A resolution to authorize representation by the Senate Legal Counsel in the case of Common Cause, et al. v. Joseph R. Biden, et al.

    THOMAS, 112th Congress

    Sen. Reid, Harry [D-NV

    2012-06-06

    06/06/2012 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S3799; text as passed Senate: CR S3799; text of measure as introduced: CR S3783) (All Actions)

  7. Managing Restored Wetlands in the Sacramento-San Joaquin Delta to Reduce Methane Emissions and Increase Carbon Uptake Laurie Koteen, Sara Knox, Cove Sturtevant, Joseph Verfaillie, Jaclyn Hatala, Dennis Baldocchi

    NASA Astrophysics Data System (ADS)

    Koteen, L. E.; Knox, S. H.; Sturtevant, C. S.; Verfaillie, J. G.; Matthes, J. H.; Baldocchi, D. D.

    2013-12-01

    The Sacramento-San Joaquin Delta of California is a region transformed by more than a century of agricultural practices. Beginning in the 19th century, substantial regions were first drained of water and then converted to cropland in order to take advantage of the area's rich peatland soils. In the intervening time period, soil oxidation and subsidence have led to huge peat losses of up to 10 m in some places, and river water now threatens to topple the levees that were erected to keep fields from flooding. Within this region, we have been monitoring greenhouse gas exchange of several agricultural sites, a degraded pasture, and two restored wetlands. Of these land use types, restoration of wetlands is of particular interest to Delta managers as these sites attain many of the region's most pressing ecological goals, including improved water quality, increased wildlife habitat, and soil accretion. In our current investigation, we hope to assess if wetland management activities can be implemented to achieve greenhouse gas management goals as well. While we find that the restored wetlands are able to take up and store a substantial amount of carbon via rapid growth rates, they also emit methane; a greenhouse gas 25 times more potent than CO¬2. We are currently in the process of implementing two management activities with the goals of reducing methane emissions and increasing carbon uptake. Evidence from the wetland literature indicates that periodic lowering of the water table below the soil surface can reduce wetland methane emissions by: 1. Reintroducing oxygen into the soil column. This both supports growth of the methanotrophic bacteria that consume methane produced in the anaerobic zones of the soil column, and suppresses the methanogens that produce it. 2. Re-oxidization of formerly reduced compounds in the soil, (i.e. NO3-, SO42-) which can serve as alternative terminal electron acceptors of the decomposition byproducts (i.e. H2 and acetate) that lead to methane formation. Under these conditions, it becomes more energetically favorable for alternative chemical transformations to occur in which CO2 and not CH4¬ is released. A second management activity would be implemented to see if wetland carbon uptake could be increased. As wetlands mature, perennial wetland vegetation often develops a significant thatch layer which can reduce photosynthesis of growing shoots by blocking radiation from leaf surfaces. Here we propose to remove the stalks of established vegetation. This would serve two goals: 1. Decomposing vegetation would be incorporated into the soil, leading to soil accretion, and 2. Thatch removal would liberate fledgling shoots, potentially increasing carbon uptake through subsequent seasons. A third investigation would compare CO2 and CH4 fluxes at an existing tower atop low salinity sediments with a new tower where site salinity is relatively high. This effort would inform new site selection efforts for wetland restoration projects. Sites located closer to the San Francisco Bay Area are tidally-influenced, and therefore have higher salinity than the impounded freshwater systems of our current study within the Delta region.

  8. Book Review: True genius: the life and science of John Bardeen. Lillian Hoddeson and Vicki Daitch, Joseph Henry Press, Washington, DC, 2002, 467pp., US 27.95, ISBN 0309084083

    NASA Astrophysics Data System (ADS)

    Ambegaokar, Vinay

    Chapters 2-16 of this work contain a meticulously researched recreation of the life and scientific career of John Bardeen, the only person to be awarded two Nobel Prizes in physics. The book-which has taken over a decade to complete-is based on all available archival sources, as well as extensive oral interviews with family, friends, and colleagues. It captures very well the heritage, values, passions, and personality of its hero. It also provides a broad yet detailed view of his scientific creations. He is fortunate indeed to have had such fine and dedicated biographers engaged in what they describe as a labor of love.

  9. Celebrating the 200th Anniversary of the Emigration of Joseph Priestley. Abstracts and Program for the Biennial Conference on Chemical Education (13th, Lewisburg, PA, July 31-August 4, 1994).

    ERIC Educational Resources Information Center

    American Chemical Society, Easton, PA. Div. of Chemical Education.

    Included in this proceedings are: (1) letters to conferees; (2) conference chairpersons; (3) symposia listing; (4) chemical demonstrations, listing and abstracts; (5) "birds-of-a-feather" sessions, listing and abstracts (informal sessions providing an opportunities for people with similar interests to meet); (6) workshop listings; (7) symposia…

  10. To designate the facility of the United States Postal Service located at 1 Walter Hammond Place in Waldwick, New Jersey, as the "Staff Sergeant Joseph D'Augustine Post Office Building".

    THOMAS, 113th Congress

    Rep. Garrett, Scott [R-NJ-5

    2013-04-10

    06/18/2014 Received in the Senate and Read twice and referred to the Committee on Homeland Security and Governmental Affairs. (All Actions) Tracker: This bill has the status Passed HouseHere are the steps for Status of Legislation:

  11. 20. A PHOTO IMAGE OF THE NORTH BANK OF THE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. A PHOTO IMAGE OF THE NORTH BANK OF THE ST. JOSEPH'S RIVER IN THE VICINITY OF THE BRIDGE. - County Line Bridge, Spanning St. Joseph River at State Route 219, 0.6 mile south of U.S. Route 20, Osceola, St. Joseph County, IN

  12. 18. A VIEW EAST, SHOWING THE HEAVILY WOODED BANKS OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. A VIEW EAST, SHOWING THE HEAVILY WOODED BANKS OF THE ST. JOSEPH RIVER. THIS IS TYPICAL OF THE RIVERSIDE ENVIRONMENT OF THE BRIDGE. - County Line Bridge, Spanning St. Joseph River at State Route 219, 0.6 mile south of U.S. Route 20, Osceola, St. Joseph County, IN

  13. 33 CFR 80.810 - Cape San Blas, FL to Perdido Bay, FL.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., FL to Perdido Bay, FL. (a) A line drawn from St. Joseph Bay Entrance Range A Rear Light through St. Joseph Bay Entrance Range B Front Light to St. Joseph Point. (b) A line drawn across the mouth of Salt... Choctawatchee Bay Entrance Jetties. (g) An east-west line drawn from Fort McRee Leading Light across...

  14. 33 CFR 80.810 - Cape San Blas, FL to Perdido Bay, FL.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., FL to Perdido Bay, FL. (a) A line drawn from St. Joseph Bay Entrance Range A Rear Light through St. Joseph Bay Entrance Range B Front Light to St. Joseph Point. (b) A line drawn across the mouth of Salt... Choctawatchee Bay Entrance Jetties. (g) An east-west line drawn from Fort McRee Leading Light across...

  15. 31 CFR 359.3 - What special terms do I need to know to understand this part?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... in definitive form registered “John Doe SSN 123-45-6789 POD (payable on death to) Joseph Doe.” In the... security registered “John Doe SSN 123-45-6789 POD (payable on death to) Joseph Doe SSN 987-65-4321.” In these examples, Joseph Doe is the beneficiary. Book-entry bond means a Series I savings bonds...

  16. 31 CFR 359.3 - What special terms do I need to know to understand this part?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... in definitive form registered “John Doe SSN 123-45-6789 POD (payable on death to) Joseph Doe.” In the... security registered “John Doe SSN 123-45-6789 POD (payable on death to) Joseph Doe SSN 987-65-4321.” In these examples, Joseph Doe is the beneficiary. Book-entry bond means a Series I savings bonds...

  17. 31 CFR 359.3 - What special terms do I need to know to understand this part?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... in definitive form registered “John Doe SSN 123-45-6789 POD (payable on death to) Joseph Doe.” In the... security registered “John Doe SSN 123-45-6789 POD (payable on death to) Joseph Doe SSN 987-65-4321.” In these examples, Joseph Doe is the beneficiary. Book-entry bond means a Series I savings bonds...

  18. 77 FR 16316 - Kentucky Disaster Number KY-00044

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-20

    ...: Jefferson, Switzerland. Kentucky: Bourbon, Clark, Fleming, Gallatin, Henry, Lewis, Nicholas, Owen, Pike... unchanged. (Catalog of Federal Domestic Assistance Numbers 59002 and 59008) Joseph P. Loddo,...

  19. 78 FR 34702 - North Dakota Disaster #ND-00037

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-10

    ..., Cass, Cavalier, Eddy, Foster, McHenry, Pembina, Ramsey, Renville, Richland, Rolette, Towner, Traill... 135976. (Catalog of Federal Domestic Assistance Numbers 59002 and 59008) Joseph P. Loddo,...

  20. 75 FR 51507 - Iowa Disaster #IA-00024

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-20

    ... and Economic Injury Loans): Black Hawk, Cherokee, Clayton, Decatur, Delaware, Dubuque, Fayette... economic injury is 122800. (Catalog of Federal Domestic Assistance Numbers 59002 and 59008) Joseph P....

  1. 77 FR 67020 - Performance Review Board Appointments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-08

    ..., Michael Black, Michael Black, Steven Blanchard, Mary Josie Bolton, Hannibal Burden, John Burzyk, Carla..., David Velasco, Janine Ward, Joseph Weber, Wendi Welch, Ruth Wells, Sandra Wenk, Daniel Wessels,...

  2. 75 FR 51506 - Iowa Disaster Number IA-00026

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-20

    ... following areas as adversely affected by the disaster. Primary Counties: Black Hawk, Boone, Buchanan... Federal Domestic Assistance Numbers 59002 and 59008) Joseph P. Loddo, Acting Associate Administrator...

  3. 78 FR 73568 - Senior Executive Service-Performance Review Board

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-06

    .... FOR FURTHER INFORMATION CONTACT: Carmen Garcia, Employee Services--OPM Human Resources, Office of... Officer Joseph Kennedy, Associate Director for Human Resources Solutions Mark Reinhold, Chief...

  4. 77 FR 41874 - Florida Disaster #FL-00071

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-16

    ..., Jefferson, Leon, Liberty, Nassau, Pinellas, Polk, Putnam, Sumter, Suwannee, Union. Georgia: Charlton, Clinch... and 59008) Joseph P. Loddo, Acting Associate Administrator for Disaster Assistance. BILLING CODE...

  5. Teaching Invisible Culture: Classroom Practice and Theory.

    ERIC Educational Resources Information Center

    Lo Bianco, Joseph, Ed.; Crozet, Chantal, Ed.

    This collection of papers discusses what researchers and classroom teachers think and do about culture in language education. There are nine chapters in two parts. Part 1, "Culture Theory," includes the following: (1) "Common Themes" (Joseph Lo Bianco); (2) "Culture: Visible, Invisible and Multiple" (Joseph Lo Bianco); and (3) "A Conceptual…

  6. 78 FR 77151 - Notice of Senior Executive Service Performance Review Board Appointments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-20

    ..., Bret Creech Black, Michael S. Blanchard, Mary Josie Boling, Edward A. Bolton, Hannibal Bowker, Bryan L...-Davis, Laura E. Darnell, Joseph D. Davis, Mark H. Dean, Francis J. Deerinwater, Daniel J. Delaplaine, L.... Wainman, Barbara V. Walker, William T. Walkoviak, Larry P. Walsh, Noreen E. Ward, Joseph M. Jr....

  7. 78 FR 2687 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-14

    ... County Black, L.A., Rice Milling Association Inc. Office, 508 S. Monroe St., DeWitt, 12001229 Columbia... Orleans, 12001241 MISSOURI Buchanan County Ryan Block, (St. Joseph MPS (AD)) 1137-1141 Frederick Ave., Saint Joseph, 12001242 St. Louis Independent city Alligator Oil Clothing Company Building,...

  8. 78 FR 36424 - Special Local Regulations for Summer Events; Captain of the Port Lake Michigan Zone

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-18

    ... Department of Homeland Security FR Federal Register NPRM Notice of Proposed Rulemaking TFR Temporary Final..., contact or email MST1 Joseph McCollum, U.S. Coast Guard Sector Lake Michigan, at 414-747-7148 or Joseph.P...-propelled vessels within a portion of the Black River in South Haven, MI. The organizer for this...

  9. Perspectives on Ethnicity in New Orleans.

    ERIC Educational Resources Information Center

    Cooke, John, Ed.

    This pamphlet contains several essays on the culture and ethnic groups of New Orleans, Louisiana. Included are: (11 a discussion by Joseph Logsdon on the uniqueness of New Orleans culture, marked by its cuisine, interethnic mixtures, and its politics; (2) an article on theories of ethnicity and neo ethnicity, by Joseph V. Guillotte, III; (3) a…

  10. Being Creative "Inside the Box"

    ERIC Educational Resources Information Center

    Tomascoff, Rocky

    2011-01-01

    Artist Joseph Cornell (1903-1972) created wonderful environments inside boxes using mostly found objects. They were often Surrealistic in nature. Some boxes were designed with glass fronts, and others were meant to be interactive with the viewer, wherein the objects could be handled. With Joseph Cornell in mind, the author introduces an art…

  11. "Method Is Education:" Making Informal Education Social and Substantive

    ERIC Educational Resources Information Center

    Stern, Miriam Heller

    2007-01-01

    This article presents the author's response to Joseph Reimer's essay titled, "Beyond More Jews Doing Jewish: Clarifying the Goals of Informal Jewish Education." Joseph Reimer states that the challenge for informal education is to move beyond socialization to clarify and achieve "deeper" educational goals. Distinguishing between socialization and…

  12. Nature, Nurture, and Attention Deficit Hyperactivity Disorder.

    ERIC Educational Resources Information Center

    Faraone, Stephen V.; Biederman, Joseph

    2000-01-01

    Comments on Joseph's review of the genetics of attention deficit disorder, demonstrating errors of scientific logic and oversight of relevant research in Joseph's argument. Argues for the validity of twin studies in supporting a genetic link for ADHD and for the complementary role of nature and nurture in the etiology of the disorder. (JPB)

  13. 75 FR 53021 - Proposed Collection; Comment Request for Regulation Project

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-30

    ... CONTACT: Requests for additional information or copies of the regulations should be directed to R. Joseph... clarity of the information to be collected; (d) ways to minimize the burden of the collection of..., and purchase of services to provide information. Approved: August 17, 2010. R. Joseph Durbala, IRS...

  14. 75 FR 61244 - Proposed Collection; Comment Request for Regulation Project

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-04

    ...: Requests for additional information or copies of the regulations should be directed to R. Joseph Durbala at...; (c) ways to enhance the quality, utility, and clarity of the information to be collected; (d) ways to...: September 28, 2010. R. Joseph Durbala, IRS Tax Analyst. BILLING CODE 4830-01-P...

  15. 78 FR 29206 - Proposed Collection; Comment Request for Regulation Project

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-17

    ... consideration. ADDRESSES: Direct all written comments to R. Joseph Durbala, Internal Revenue Service, Room 6129..., utility, and clarity of the information to be collected; (d) ways to minimize the burden of the collection..., maintenance, and purchase of services to provide information. Approved: May 1, 2013. R. Joseph Durbala,...

  16. 75 FR 53019 - Proposed Collection; Comment Request for Regulation Project

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-30

    ... regulations should be directed to R. Joseph Durbala at Internal Revenue Service, room 6129, 1111 Constitution... enhance the quality, utility, and clarity of the information to be collected; (d) ways to minimize the.... R. Joseph Durbala, IRS Tax Analyst. BILLING CODE 4830-01-P...

  17. 75 FR 61241 - Proposed Collection: Comment Request for Regulation Project

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-04

    ... or copies of the regulation should be directed to R. Joseph Durbala, at (202) 622-3634, or at... collected; (d) ways to minimize the burden of the collection of information on respondents, including... provide information. Approved: September 28, 2010. R. Joseph Durbala, IRS Tax Analyst. BILLING CODE...

  18. 75 FR 11637 - Proposed Collection; Comment Request for Regulation Project

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-11

    ...: Direct all written comments to R. Joseph Durbala, Internal Revenue Service, room 6129, 1111 Constitution... collected; (d) ways to minimize the burden of the collection of information on respondents, including... provide information. Approved: March 5, 2010. R. Joseph Durbala, IRS Supervisory Tax Analyst. BILLING...

  19. 75 FR 11996 - Proposed Collection; Comment Request for Regulation Project

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-12

    ...: Direct all written comments to R. Joseph Durbala, Internal Revenue Service, room 6129, 1111 Constitution... collected; (d) ways to minimize the burden of the collection of information on respondents, including... provide information. Approved: February 22, 2010. R. Joseph Durbala, IRS Supervisory Tax Analyst....

  20. 76 FR 37195 - Proposed Collection; Comment Request for Regulation Project

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-24

    ... consideration. ADDRESSES: Direct all written comments to R. Joseph Durbala, Internal Revenue Service, Room 6129... information; (c) ways to enhance the quality, utility, and clarity of the information to be collected; (d... information. ] Approved: June 21, 2011. R. Joseph Durabala, IRS Reports Clearance Officer. BILLING CODE...

  1. 78 FR 28943 - Proposed Collection; Comment Request for Regulation Project

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-16

    ..., 2013 to be assured of consideration. ADDRESSES: Direct all written comments to R. Joseph Durbala... clarity of the information to be collected; (d) ways to minimize the burden of the collection of..., and purchase of services to provide information. Approved: May 6, 2013. R. Joseph Durbala, OMB...

  2. 75 FR 53737 - Proposed Collection; Comment Request for Regulation Project

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-01

    ... directed to R. Joseph Durbala at Internal Revenue Service, Room 6129, 1111 Constitution Avenue, NW..., utility, and clarity of the information to be collected; (d) ways to minimize the burden of the collection..., maintenance, and purchase of services to provide information. Approved: August 24, 2010. R. Joseph...

  3. 75 FR 53023 - Proposed Collection; Comment Request for Regulation Project

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-30

    ... regulations should be directed to R. Joseph Durbala at Internal Revenue Service, room 6129, 1111 Constitution... clarity of the information to be collected; (d) ways to minimize the burden of the collection of..., and purchase of services to provide information. Approved: August 23, 2010. R. Joseph Durbala, IRS...

  4. 75 FR 56659 - Proposed Collection; Comment Request for Regulation Project

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-16

    ... information or copies of the regulation should be directed to R. Joseph Durbala (202) 622-3634, Internal...; (c) ways to enhance the quality, utility, and clarity of the information to be collected; (d) ways to...: September 7, 2010. R. Joseph Durbala, IRS Tax Analyst. BILLING CODE 4830-01-P...

  5. 75 FR 53739 - Proposed Collection: Comment Request for Regulation Project

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-01

    ... additional information or copies of the regulation should be directed to R. Joseph Durbala, at (202) 622-3634... collected; (d) ways to minimize the burden of the collection of information on respondents, including... provide information. Approved: August 24, 2010. R. Joseph Durbala, IRS Tax Analyst. BILLING CODE 4830-01-P...

  6. 78 FR 17470 - Proposed Collection; Comment Request for Regulation Project

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-21

    ... before May 20, 2013 to be assured of consideration. ADDRESSES: Direct all written comments to R. Joseph... collected; (d) ways to minimize the burden of the collection of information on respondents, including... provide information. Approved: March 12, 2013. R. Joseph Durbala, OMB Reports Clearance Officer....

  7. 15. A CLOSE UP VIEW OF ONE OF THE EXPOSED ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. A CLOSE UP VIEW OF ONE OF THE EXPOSED AGGREGATE LAMP STANDARDS, ITS BRONZE DECORATED FERRULE AND BRONZE LENS RECEIVER. - County Line Bridge, Spanning St. Joseph River at State Route 219, 0.6 mile south of U.S. Route 20, Osceola, St. Joseph County, IN

  8. 17. DETAIL OF THE BRONZE INSCRIPTION PLACQUE, LOCATED IN A ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. DETAIL OF THE BRONZE INSCRIPTION PLACQUE, LOCATED IN A NEWEL ON THE SOUTH END OF THE BRIDGE. ALTHOUGH THE DATE ON THE PLACQUE IS 1929, THE BRIDGE WAS NOT DEDICATED UNTIL 1930. - County Line Bridge, Spanning St. Joseph River at State Route 219, 0.6 mile south of U.S. Route 20, Osceola, St. Joseph County, IN

  9. 14. PHOTO LOOKING SOUTH FROM HIGH GROUND ON THE NORTH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. PHOTO LOOKING SOUTH FROM HIGH GROUND ON THE NORTH BANK OF THE RIVER. CONCRETE DETERIORATION IS QUITE APPARENT IN THIS IMAGE. - County Line Bridge, Spanning St. Joseph River at State Route 219, 0.6 mile south of U.S. Route 20, Osceola, St. Joseph County, IN

  10. 4. THIS VIEW SHOWS PORTIONS OF THE EAST FACADE OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. THIS VIEW SHOWS PORTIONS OF THE EAST FACADE OF THE SOUTH CAUSEWAY, AS WELL AS THE THREE OPEN ARCHES OF THE BRIDGE. LOOKING NORTHWEST FROM THE SOUTH BANK OF THE RIVER. - County Line Bridge, Spanning St. Joseph River at State Route 219, 0.6 mile south of U.S. Route 20, Osceola, St. Joseph County, IN

  11. 5. AN IMAGE LOOKING SOUTH ALONG THE SIDEWALK OF THE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. AN IMAGE LOOKING SOUTH ALONG THE SIDEWALK OF THE BRIDGE, SHOWING THE MARINA ON THE FAR BANK, TO THE RIGHT. - County Line Bridge, Spanning St. Joseph River at State Route 219, 0.6 mile south of U.S. Route 20, Osceola, St. Joseph County, IN

  12. 12. A SIMILAR VIEW TO IN6804, TAKEN FARTHER DOWNRIVER FROM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. A SIMILAR VIEW TO IN-68-04, TAKEN FARTHER DOWNRIVER FROM THE SOUTH BANK. THIS VIEW SHOWS THE GRACEFUL OPEN WORK OF THE SPANDRELS, UNDER THE BRIDGE. - County Line Bridge, Spanning St. Joseph River at State Route 219, 0.6 mile south of U.S. Route 20, Osceola, St. Joseph County, IN

  13. Interventions for Increasing the Academic Engagement of Students with Autism Spectrum Disorders in Inclusive Classrooms

    ERIC Educational Resources Information Center

    Goodman, Gay; Williams, Cathy M.

    2007-01-01

    Joseph, a student with autism in Ms. Mendez's inclusion kindergarten class, experienced difficulty attending during group activities. He spent a significant amount of time looking at his hands and quoting parts of his favorite videos. Attempts to engage Joseph resulted in vocal protests and, at times, mild aggression. Ms. Mendez realized that she…

  14. Photographic copy of photograph of the Architect's rendering of the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of photograph of the Architect's rendering of the proposed Auditorium Building (1904-05) (original photograph in possession of Brunner and Brunner, Architect and Engineers, Inc., St. Joseph, Missouri) VIEW OF SOUTHEAST CORNER - Old City Auditorium, 404-424 North Fourth Street, Saint Joseph, Buchanan County, MO

  15. 7. Detail view north of stone wall and wood gate ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Detail view north of stone wall and wood gate between Ten Acre Lot (foreground) and Barn Meadow (background) with Joseph Fry Farm complex beyond - Joseph Fry Farm Landscape, 2153 South County Trail Road (U.S. Route 2), East Greenwich, Kent County, RI

  16. 1. View north from StanleyBostitch property toward southern boundary/stone wall ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. View north from Stanley-Bostitch property toward southern boundary/stone wall of Joseph Fry Farm with South County Trail/Route 2 to the east (right) - Joseph Fry Farm Landscape, 2153 South County Trail Road (U.S. Route 2), East Greenwich, Kent County, RI

  17. The Discovery of Oxygen and Other Priestley Matters

    NASA Astrophysics Data System (ADS)

    Williams, Kathryn R.

    2003-10-01

    Joseph Priestley has been the subject of several JCE papers, including a bicentennial celebration by Roy G. Neville (JCE, 1974, 51, 428-31) of Priestley's discovery of oxygen. This look to the past revisits Neville's account and other sources on the multi-faceted life of Joseph Priestley.

  18. 4. Detail view north of stone wall opening between Five ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Detail view north of stone wall opening between Five Acre Lot (foreground) and Ten Acre Lot (background) with Joseph Fry Farm complex beyond - Joseph Fry Farm Landscape, 2153 South County Trail Road (U.S. Route 2), East Greenwich, Kent County, RI

  19. Returning to the Reservation: Experiences of a First Year Native American Teacher.

    ERIC Educational Resources Information Center

    Blasi, MaryJane W.

    A case study of the experiences of a Native American teacher (Joseph) during his first year of teaching examined the transition from the idealistic world of college to the stark realities of actual teaching. Data were gathered through bimonthly semistructured interviews, classroom observations, and telephone communication. Joseph picked a…

  20. 77 FR 53887 - Change in Bank Control Notices; Acquisitions of Shares of a Savings and Loan Holding Company

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-04

    ... 64198-0001: 1. Billy D. Cole and Joy Y. Cole, St. Joseph, Missouri; Nancy Stonner, Blue Springs, Missouri; Norma Cole, Redmond, Washington; Mary Benson, New York, New York; and Thomas Cole, Liberty, Missouri; as a group acting in concert, to acquire control of St. Joseph Bancorp, Inc., and...

  1. 76 FR 11240 - Qualified Hydro 34, LLC; Notice of Preliminary Permit Application Accepted for Filing and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-01

    ...) of the Federal Power Act (FPA), proposing to study the feasibility of the Foster Joseph Sayers Dam Hydroelectric Project to be located on Bald Eagle Creek in the vicinity of Liberty Township in Centre County... Engineers' Foster Joseph Sayers Dam and would consist of the following: (1) One vertical Kaplan turbine...

  2. 76 FR 31843 - Safety Zone; Temporary Change to Enforcement Location of Recurring Fireworks Display Event...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-02

    ... INFORMATION CONTACT: If you have questions on this temporary rule, call or e-mail CWO3 Joseph M. Edge, Coast Guard Sector North Carolina, Coast Guard; telephone 252-247-4525, e-mail Joseph.M.Edge@uscg.mil . If you... responsiveness to small business. If you wish to comment on actions by employees of the Coast Guard, call...

  3. Composing Self on Narrative Landscapes of Sexual Difference: A Story of Wisdom and Resilience

    ERIC Educational Resources Information Center

    Estefan, Andrew; Roughley, Robert A.

    2013-01-01

    This study draws upon recent narrative inquiry research that explored the resilience experiences of 6 young same-sex-attracted men and women (4 men, 2 women; age range = 21-27). This article elucidates the story of one participant, Joseph, a 25-year-old Canadian man. As we conducted the research, Joseph's story stood out for us as having something…

  4. Pilates and Mindfulness: A Qualitative Study

    ERIC Educational Resources Information Center

    Adams, Marianne; Caldwell, Karen; Atkins, Laurie; Quin, Rebecca

    2012-01-01

    The Pilates method as Joseph Hubertus Pilates originally defined it in the early 1920s, was called "Contrology," or the art of control, based on the ideal of attaining a complete coordination of body, mind, and spirit. Joseph Pilates's early writings emphasized the value of controlling the body rather than attending to the process of body…

  5. A resolution commending the African Union for committing to a coordinated military response, comprised of 5,000 troops from Uganda, the Central African Republic, the Democratic Republic of Congo, and South Sudan, in order to fortify ongoing efforts to arrest Joseph Kony and senior commanders of the Lord's Resistance Army and to stop the crimes against humanity and mass atrocities committed by them.

    THOMAS, 112th Congress

    Sen. Landrieu, Mary L. [D-LA

    2012-03-29

    03/29/2012 Referred to the Committee on Foreign Relations. (text of measure as introduced: CR S2257-2258) (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  6. Erratum: Suicidal ideation and suicide attempts in five groups with different severities of gambling: Findings from the National Epidemiologic Survey on Alcohol and Related Conditions by Jacquelene F. Moghaddam, Gihyun Yoon, Daniel L. Dickerson, Suck Won Kim, and Joseph Westermeyer DOI: 10.1111/ajad.12197.

    PubMed

    2015-12-01

    In Ref.[1], the following error was published under the Declaration of Interest. The article erroneously acknowledged the receipt of a funding source #1R01AA022066-01. We apologize for this error. PMID:26767449

  7. Empirical Evidence of Social and Emotional Learning's Influence on School Success: A Commentary on "Building Academic Success on Social and Emotional Learning: What Does the Research Say?," a Book Edited by Joseph E. Zins, Roger P. Weissberg, Margaret C. Wang, and Herbert J. Walberg

    ERIC Educational Resources Information Center

    Taylor, Rebecca D.; Dymnicki, Allison B.

    2007-01-01

    In Building Academic Success on Social and Emotional Learning: What does the Research Say? Zins and his colleagues presented a new way to conceptualize the impact of social and emotional learning programs on students' school success by broadening the concept to include students' attitudes, behaviors, and performance. To build on Zins' ideas, we…

  8. Microbial Extracellular Enzyme Activity and Community Assembly Processes Post Fire Disturbance Amanda Labrado, University of Texas at El Paso; Emily B. Graham, University of Colorado Boulder; Joseph E. Knelman, University of Colorado Boulder; Scott Ferrenberg, University of Colorado Boulder; Diana R. Nemergut, University of Colorado Boulder

    NASA Astrophysics Data System (ADS)

    Labrdo, A.; Knelman, J. E.; Graham, E. B.; Ferrenberg, S.; Nemergut, D. R.

    2013-12-01

    Microbes control major biogeochemical cycles and can directly impact the carbon, nitrogen, and phosphorus pools and fluxes of soils. However, many questions remain regarding when and where data on microbial community structure are necessary to accurately predict biogeochemical processes. In particular, it is unknown how shifts in microbial assembly processes may relate to changes in the relationship between community structure and ecosystem function. Here, we examine soil microbial community assembly processes and extracellular enzyme activity (EEA) at 4-weeks and 16-weeks after the Fourmile Canyon Fire in Boulder, CO in order to determine the effects of disturbance on community assembly and EEA. Microbial community structure was determined from 16S rRNA gene pyrosequencing, edaphic properties were determined using standard biogeochemical assays, and extracellular enzyme activity for β-1, 4-glucosidase (BG) and β-1, 4-N-acetylglucosaminidase (NAG) enzymes were determined using fluorimetric assays. Stepwise linear regressions were used to determine the effects of microbial community structure and edaphic factors on EEA. We determined that in 4-week post fire samples EEA was only correlated with microbial predictors. However, we observed a shift with 16-week samples in which EEA was significantly related to edaphic predictors. Null derivation analysis of community assembly revealed that communities in the 4-week samples were more neutrally assembled than communities in the 16-week samples. Together, these results support a conceptual model in which the relationship between edaphic factors and ecosystem processes is somewhat decoupled in more neutrally assembled communities, and data on microbial community structure is important to most accurately predict function.

  9. Simulation of a tagged neutron inspection system prototype

    NASA Astrophysics Data System (ADS)

    Donzella, A.; Boghen, G.; Bonomi, G.; Fontana, A.; Formisano, P.; Pesente, S.; Sudac, D.; Valkovic, V.; Zenoni, A.

    2006-05-01

    The illicit trafficking of explosive materials in cargo containers has become, in recent years, a serious problem. Currently used X-ray or γ-ray based systems provide only limited information about the elemental composition of the inspected cargo items. During the last years, a new neutron interrogation technique, named TNIS (Tagged Neutron Inspection System), has been developed, which should permit to determine the chemical composition of the suspect item by coincidence measurements between alpha particles and photons produced. A prototype of such a system for container inspection has been built, at the Institute Ruder Boskovic (IRB) in Zagreb, Croatia, for the European Union 6FP EURITRACK project. We present the results of a detailed simulation of the IRB prototype performed with the MCNP Monte Carlo program and a comparison with beam attenuation calculations performed with GEANT3/MICAP. Detector signals, rates and signal over background ratios have been calculated for 100 kg of TNT explosive located inside a cargo container filled with a metallic matrix of density 0.2 g/cm3. The case of an organic filling material is discussed too.

  10. 78 FR 28602 - Announcement of Funding Awards for the Public and Indian Housing Resident Opportunity and Self...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-15

    ... CONTACT: Joseph E. Taylor, Grants Management Center, Office of Public and Indian Housing, Department of... Authority of the City of 209 Madison Street. Frederick MD......... 21701 216,000 Frederick....

  11. Genetics Home Reference: Lujan syndrome

    MedlinePlus

    ... Briault S, Skinner C, Bauer-Carlin A, Simensen RJ, Joseph SM, Jones JR, Gecz J, Stratton MR, Raymond ... National Institutes of Health National Library of Medicine Lister Hill National Center for Biomedical Communications 8600 Rockville ...

  12. Kirschvink receives 2011 William Gilbert Award: Citation

    NASA Astrophysics Data System (ADS)

    Weiss, Benjamin P.

    2012-04-01

    Joseph Kirschvink received the William Gilbert Award at the 2011 AGU Fall Meeting, held 5-9 December in San Francisco, Calif. The award recognizes outstanding and unselfish work in magnetism of Earth materials and of the Earth and planets.

  13. Kirschvink receives 2011 William Gilbert Award: Response

    NASA Astrophysics Data System (ADS)

    Kirschvink, Joseph L.

    2012-04-01

    Joseph Kirschvink received the William Gilbert Award at the 2011 AGU Fall Meeting, held 5-9 December in San Francisco, Calif. The award recognizes outstanding and unselfish work in magnetism of Earth materials and of the Earth and planets.

  14. Code AI Personal Web Pages

    NASA Technical Reports Server (NTRS)

    Garcia, Joseph A.; Smith, Charles A. (Technical Monitor)

    1998-01-01

    The document consists of a publicly available web site (george.arc.nasa.gov) for Joseph A. Garcia's personal web pages in the AI division. Only general information will be posted and no technical material. All the information is unclassified.

  15. 2. West and south elevation. Copied from an old print ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. West and south elevation. Copied from an old print by Joseph Hill, lent to survey by Evelyn S. Craig. - Jansonist Colony, Steeple Building, Main & Bishop Hill Streets, Bishop Hill, Henry County, IL

  16. 2. Historic American Buildings Survey Copied from an old print ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Historic American Buildings Survey Copied from an old print by Joseph Hill. OLD STORE AND POST OFFICE, FROM 'HISTORIC BISHOP HILL'- EVELYN S. CRAIG - Jansonist Colony, Colony Store & Post Office, Main & Bishop Hill Streets, Bishop Hill, Henry County, IL

  17. 77 FR 42339 - Improving Contracting Officers' Access to Relevant Integrity Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-18

    ... BUDGET Office of Federal Procurement Policy Improving Contracting Officers' Access to Relevant Integrity... information about contractor business ethics in the Federal Awardee Performance and Integrity Information.../omb/procurement/frn/frn-access-to-relevant-integrity-information-public-comments.pdf . Joseph...

  18. 77 FR 5307 - Agency Information Collection Activity; Proposed Collection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-02

    ... Internal Revenue Service Agency Information Collection Activity; Proposed Collection AGENCY: Internal... consideration. ADDRESSES: Direct all written comments to Yvette Lawrence, Internal Revenue Service, room 6129... additional information or copies of the regulations should be directed to R. Joseph Durbala at...

  19. What You Need to Know If You Have Coronary Artery Disease

    MedlinePlus

    ... Genetics → Circ: Cardiovascular Imaging → Circ: Cardiovascular Interventions → Circ: Cardiovascular ... Know If You Have Coronary Artery Disease Joseph S. Alpert Download PDF http://dx.doi.org/ ...

  20. Seven Democratic Presidential Candidates Debate Educational Issues.

    ERIC Educational Resources Information Center

    Equity and Excellence, 1988

    1988-01-01

    Provides the transcript of a debate on educational issues among Democratic presidential candidates Paul Simon, Albert Gore, Joseph Biden, Jesse Jackson, Bruce Babbitt, Richard Gephart, and Michael Dukakis. (BJV)

  1. 8. INTERIOR BEADED WALL BOARDING SHOWING TRIAL MARKS FROM DIES ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. INTERIOR BEADED WALL BOARDING SHOWING TRIAL MARKS FROM DIES MADE IN CARPENTER'S SHOP Ph: Jack E, Boucher - March 1961 - Joseph Carpenter Silversmith Shop, 71 East Town Street, Norwichtown, New London County, CT

  2. 78 FR 5442 - Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-25

    ... Palen, Lorraine Palen, and Joseph Palen, individually and as co-trustees of the Palen Marital Trust, Elizabeth Dray and Judith Somers, all of Forrest, Illinois; Marie King, Piper City, Illinois; and...

  3. 7. Historic American Buildings Survey Carl Magro, Photographer May 1936, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Historic American Buildings Survey Carl Magro, Photographer May 1936, Copied by Joseph Hill. VALVE CONTROL LEVERS ON WEST GATE - Illinois & Michigan Canal, Locks & Lockhouse, Channahon, Will County, IL

  4. Aspirin overdose

    MedlinePlus

    Acetylsalicylic acid (aspirin) can be found in many prescription and over-the-counter pain relievers, including: Alka Seltzer Anacin Bayer Bufferin Ecotrin Excedrin Fiorinal Percodan St. Joseph's Note: This list may not be all-inclusive.

  5. Lithium Beats Newer Meds for Bipolar Disorder, Study Finds

    MedlinePlus

    ... such as valproate (Depacon, Depakote), olanzapine (Zyprexa) or quetiapine (Seroquel), said lead researcher Joseph Hayes. He is ... his colleagues found. And people on valproate or quetiapine were 32 percent to 34 percent more likely ...

  6. NOAA Looks for Advice to Make Its Data Easier to Use

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2014-03-01

    "There is no sector in American business that wouldn't like to have better environmental information," said Joseph Klimavicz, chief information officer for the National Oceanic and Atmospheric Administration (NOAA).

  7. 22. Greenhouse, south elevation. This winter 2002 view was taken ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. Greenhouse, south elevation. This winter 2002 view was taken by Joseph Elliot while conducting photographic documentation of the landscape. - John Bartram House & Garden, Greenhouse, 54th Street & LIndbergh Boulevard, Philadelphia, Philadelphia County, PA

  8. Success to the Third Degree.

    ERIC Educational Resources Information Center

    Joiner, Lottie L.

    2001-01-01

    Tasha Inniss, Sherry Scott Joseph, and Kimberly Weems discuss the challenges and successes of becoming the first African American women to receive doctorates in mathematics from the University of Maryland-College Park. (EV)

  9. Hey! A Fire Ant Stung Me!

    MedlinePlus

    ... play with it. Reviewed by: Elana Pearl Ben-Joseph, MD Date reviewed: April 2016 For Teens For Kids For Parents MORE ON THIS TOPIC Camping and Woods Safety Hey! A Black Widow Spider Bit Me! Learning About Allergies Hey! ...

  10. 78 FR 8162 - Changes in Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-05

    ... of East Haven The Honorable Joseph 461 North High October 5, 2012 090076 Docket No.: B-1277). (11-01... Montrose IL 60446. Drive, Romeoville, IL 60446. Iowa: Black Hawk (FEMA Docket City of Cedar Falls...

  11. 77 FR 61744 - Export Trade Certificate of Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-11

    ... issued on May 13, 2010 (75 FR 29514, May 26, 2010). FOR FURTHER INFORMATION CONTACT: Joseph E. Flynn... meaning of section 325.2(l) of the Regulations (15 CFR 325.2(l)): Glacier Bay Fisheries, LLC....

  12. 75 FR 24721 - Agency Information Collection Activities: Extension of an Existing Information Collection...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-05

    ... SECURITY United States Immigration and Customs Enforcement Agency Information Collection Activities... Homeland Security, U.S. Immigration and Customs Enforcement (USICE), has submitted the following...), Joseph M. Gerhart, Chief, Records Management Branch, U.S. Immigration and Customs Enforcement, 500...

  13. 33. Coal Fuel Elevator (diagonal in foreground), Fuel Elevator (left), ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    33. Coal Fuel Elevator (diagonal in foreground), Fuel Elevator (left), Fuel Storage Bins (center), and Power Plant (right) Photographs taken by Joseph E.B. Elliot - Huber Coal Breaker, 101 South Main Street, Ashley, Luzerne County, PA

  14. Commemorative Displays: Bridging the Gap Between Past and Present.

    ERIC Educational Resources Information Center

    Stock, John T.

    1984-01-01

    Suggests preparing displays which include both dynamic and static items to attract observers' attention and hold their interest. Includes instructions for making exhibits related to phenomena associated with Joseph Priestley and Michael Faraday. (DH)

  15. "Enemies of the People": Poetry and Politics in the Time of Stalin.

    ERIC Educational Resources Information Center

    Morse, David

    2001-01-01

    Discusses the role of writers in Russia during the period of Joseph Stalin to enlighten issues related to intellectual freedom. Includes an annotated bibliography on "Russian Literature of the Soviet Period," to help students learn more about Russia. (CMK)

  16. Detail view of the exposed polychromatic aggregate ceiling designed and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of the exposed polychromatic aggregate ceiling designed and cast by John Joseph Earley for the vehicular entrance portals to the courtyard - United States Department of Justice, Constitution Avenue between Ninth & Tenth Streets, Northwest, Washington, District of Columbia, DC

  17. "Bionic Man" Showcases Medical Research | NIH MedlinePlus the Magazine

    MedlinePlus

    ... courtesy of Joseph Hippensteel, University of Wisconsin Implantable Sensors for Prosthesis Control Implantable myoelectric (electrical properties of ... painlessly and doesn't require refrigeration. Interstitial Pressure Sensor Interstitial pressure sensor could help doctors determine optimal ...

  18. Infant Ear Infections Becoming Less Common

    MedlinePlus

    ... who is director of pediatric otolaryngology at the New York Eye and Ear Infirmary of Mount Sinai, in New ... Galveston; Joseph Bernstein, M.D., director, pediatric otolaryngology, New York Eye and Ear Infirmary of Mount Sinai, New York ...

  19. Piriformis syndrome

    MedlinePlus

    ... sciatica; Hip socket neuropathy; Pelvic outlet syndrome; Low back pain - piriformis References Joseph RL, Alleva JT, Hudgins TH. Piriformis syndrome. In: Frontera: Essentials of Physical Medicine and Rehabilitation . 3rd ed. Philadelphia, PA: Elsevier Saunders; 2014:chap ...

  20. 10. Historic American Buildings Survey Verlin Berry, Photographer November 2, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. Historic American Buildings Survey Verlin Berry, Photographer November 2, 1977 SECOND FLOOR, DETAIL OF WINDOW MOLDINGS AND RADIATOR - Kamm Building, 111 North Main Street, Mishawaka, St. Joseph County, IN