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Sample records for judy meier penn

  1. Talking with Judy Blume

    ERIC Educational Resources Information Center

    Freeman, Judy

    2005-01-01

    The believable voices of Judy Blume's characters--such as the troublemaking Fudge from "Tales of a Fourth Grade Nothing" and freckle-less Andrew from "Freckle Juice"--have charmed readers since Blume published her first book, "The One in the Middle Is the Green Kangaroo," in 1969. This article presents an interview with author Judy Blume. In this…

  2. The Kaplan-Meier Theatre

    ERIC Educational Resources Information Center

    Gerds, Thomas A.

    2016-01-01

    Survival is difficult to estimate when observation periods of individuals differ in length. Students imagine sailing the Titanic and then recording whether they "live" or "die." A clever algorithm is performed which results in the Kaplan-Meier estimate of survival.

  3. ASK Talks With Judy Stokley

    NASA Technical Reports Server (NTRS)

    Stokley, Judy

    2002-01-01

    In the summer of 1997, Judy Stokley took over as Program Director of the Air-to-Air Joint System Project Office (JSPO) at Eglin Air Force Base in Florida. As the JSPO Program Director, she directed much of her attention to reforming the Advanced Medium Range Air to Air Missile (AMRAAM) program, which had been operational since 1991 and was presently being produced for the Air Force, Navy, Marine Corps, and many international customers. Upon careful analysis of the program, she found it rife with problems. Two of the most pressing included a bloated Average Unit Procurement Cost and an Air Force mandated draw down plan that had not been met. In this interview, following her presentation at the Fourth NASA Masters Forum of Program and Project Managers in Dallas last February, Stokley discusses some of the difficulties she experienced in carrying out the AMRAAM reforms. Stokley is presently Air Force Program Executive Officer for Weapons in Washington, D.C. She is responsible for the cost, schedule, and technical performance of a portfolio of air-to-air and air-to-ground weapons programs. These programs represent the leading edge of weapons technology, including developing the next generation of precision-guided munitions -- 'smart' bombs -- and air superiority missiles.

  4. Judy Collins sings at the IMAX Theater

    NASA Technical Reports Server (NTRS)

    1999-01-01

    At the piano, singer-songwriter Judy Collins performs her original song, 'Beyond the Sky,' at the KSC Visitor Complex's Imax Theater for an audience waiting for the launch of STS-93. The song, commissioned by NASA through the Nasa Art Program, honored Eileen Collins, the first woman to command a Space Shuttle. The attendees are planning to view the launch at the Banana Creek viewing sight. Liftoff is scheduled for July 20 at 12:36 a.m. EDT.

  5. Cultural Arrogance and Realism in Judy Blume's "Superfudge."

    ERIC Educational Resources Information Center

    Nodelman, Perry

    1988-01-01

    Argues that Judy Blume's "Superfudge" presents an unrealistic, "generic" portrayal of middle class existence. Asserts that training children to identify with characters fosters personal and cultural blindness. (MM)

  6. Judy Estes Hall (1940-2015).

    PubMed

    Sammons, Morgan T; Boucher, Andrew

    2016-01-01

    Presents an obituary for Judy Estes Hall, who passed away on November 24, 2015. Hall served as the Executive Officer of the National Register of Health Service Psychologists until her retirement in 2013. She is a recognized expert in the development of education and training standards for the profession of psychology, she also made significant contributions in the field of international psychology, where she was a renowned expert in cross-national credentialing and an advocate for commonality in licensing standards. She was the coauthor of one edited volume and author of more than 60 journal articles, book chapters, and professional publications. A passionate advocate for the advancement of women in psychology, a devoted mother and grandmother, a connoisseur of wine and international traveler extraordinaire, she touched the personal and professional lives of many. (PsycINFO Database Record PMID:27504582

  7. Judy Collins shares a laugh with First Lady Hillary Clinton

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Singer Judy Collins (left) shares a laugh with First Lady Hillary Rodham Clinton in the Apollo/Saturn V Facility. Both women are at KSC to view the launch of Space Shuttle mission STS-93 scheduled for 12:36 a.m. EDT July 20. Much attention has been generated over the launch due to Commander Eileen M. Collins, the first woman to serve as commander of a Shuttle mission. Judy Collins has honored the commander with a song, 'Beyond the Sky,' which was commissioned by NASA through the NASA Art Program.

  8. Native Plants, Native Knowledge: Insights from Judy Bluehorse Skelton.

    ERIC Educational Resources Information Center

    Reed, Bracken

    2003-01-01

    Judy Bluehorse Skelton is an herbalist of Native American descent who conducts field trips to identify plants and classroom activities to demonstrate their uses. She also works with Portland (Oregon) schools developing culturally appropriate strategies for presenting Native American content. She encourages students to look at events such as the…

  9. Thinking Inclusively about Gifted Education: A Tribute to Judy Lupart

    ERIC Educational Resources Information Center

    Porath, Marion

    2012-01-01

    Dr. Judy Lupart's distinguished career is highlighted by her important contributions to the education of students with exceptional learning needs. The breadth of her vision and the range of exceptional learning needs she considered in her thinking about inclusive education changed the landscape of special education in Canada and elsewhere. Dr.…

  10. Penn State DOE GATE Program

    SciTech Connect

    Anstrom, Joel

    2012-08-31

    The Graduate Automotive Technology Education (GATE) Program at The Pennsylvania State University (Penn State) was established in October 1998 pursuant to an award from the U.S. Department of Energy (U.S. DOE). The focus area of the Penn State GATE Program is advanced energy storage systems for electric and hybrid vehicles.

  11. Judy Creek: Successful use of offset VSP to find porosity

    SciTech Connect

    Campbell, A.; Pearcy, R.; Lee, H.; Hemingson, P.

    1994-12-31

    In March of 1993, Imperial Oil Resources Ltd. drilled the Judy Creek 14-7-64-10w5 well. The target was porosity on the front of the Judy Creek ``A`` reef. The well encountered poor porosity development. Available surface seismic was of low resolution, so an alternative method was sought to locate better porosity. An offset VSP was acquired, and an anomaly was observed on the P-wave data at a distance of 125 meters form the well. A short radius horizontal radial was drilled from the existing wellbore and encountered porosity development at 125 meters from the well bore. Subsequently, S-wave processing was carried out. Once again, an anomaly was observed at 125 meters form the well bore. The S-waves had the additional advantage of providing better resolution of the porous zone than the P-wave image.

  12. 2014 Penn State Bioinorganic Workshop

    SciTech Connect

    Golbeck, John

    2015-10-01

    The 3rd Penn State Bioinorganic Workshop took place in early June 2014 and was combined with the 3rd Penn State Frontiers in Metallobiochemistry Symposium. The workshop was even larger than the 2nd Penn State Bioinorganic Workshop we offered in 2012. It had even more participants (162 rather than 123 in 2012). Like the 2012 workshop, the 2014 workshop had three parts. The first part consisted of 16 90-minute lectures presented by faculty experts on the topic of their expertise (see below). Based on the suggestions from the 2012 workshop, we have recorded all 16 lectures professionally and make them available to the entire bioinorganic community via online streaming. In addition, hard copies of the recordings are available as backup.

  13. Judy Creed CO/sub 2/ flood performance predictions

    SciTech Connect

    Delaney, R.P.; Fish, R.M.

    1980-01-01

    This work describes the studies which have been completed to evaluate the oil recovery benefits of a carbon dioxide miscible flood of the Judy Creek Beaverhill Lake, a pool in N. Alberta. Purchased and reproduced carbon dioxide will be injected into the reservoir to achieve the planned high volumes of carbon dioxide injection of over 50% pv. Laboratory tests, including slim tube displacement tests, pvt analysis, and a core flood, were conducted to determine carbon dioxide and oil properties along with the characteristics of the displacement process under a carbon dioxide flood. Conventional black oil simulation was used to model a statistical representation of the reservoir with adjustments for reservoir continuity, carbon dioxide dissolution in water, and miscible effects. These results indicated an incremental recovery over waterflood of 20% of the original oil in place.

  14. 4. photocopy of an advertisement (from Penn Alto Hotel archives, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. photocopy of an advertisement (from Penn Alto Hotel archives, Altoona, Pennsylvania) ADVERTISEMENT TO SELL STOCK IN PENN ALTO HOTEL - Penn Alto Hotel, 1120-1130 Thirteenth Avenue, Altoona, Blair County, PA

  15. 3. photocopy of an advertisement (from Penn Alto Hotel archives, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. photocopy of an advertisement (from Penn Alto Hotel archives, Altoona, Pennsylvania) ADVERTISEMENT TO SELL STOCK IN PENN ALTO HOTEL - Penn Alto Hotel, 1120-1130 Thirteenth Avenue, Altoona, Blair County, PA

  16. A TRIBUTE TO DR. WILLIAM PENN WATKINSON

    EPA Science Inventory

    Dr. William Penn Watkinson (known to colleagues as "Penn") of EPA¿s health research lab (National Health and Environmental Research Laboratory) of Research Triangle Park, North Carolina, died Wednesday, December 13 after a battle with lung cancer. He was a member of the Pulmonar...

  17. Judy Collins and First Lady Hillary Clinton await the launch of STS-93

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Singer Judy Collins (left) and First Lady Hillary Rodham Clinton await the launch of Space Shuttle mission STS-93 in the Apollo/Saturn V Facility. Liftoff is scheduled for 12:36 a.m. EDT July 20. Much attention has been generated over the launch due to Commander Eileen M. Collins, the first woman to serve as commander of a Shuttle mission. Judy Collins has honored the commander with a song, 'Beyond the Sky,' which was commissioned by NASA through the NASA Art Program.

  18. Women in History--Judy Heumann: Giving Voice and Creating Change

    ERIC Educational Resources Information Center

    Hall, Sarah A.

    2008-01-01

    This article profiles Judy Heumann, who has spent her life as an advocate for the rights of people with disabilities. She advocates for the full appropriate implementation of the Individuals with Disabilities Education Act and other related antidiscrimination legislation. Her ultimate goal is for people with disabilities "not to be seen as…

  19. The Great Unknown: Daniel Handler Interviews National Book Award-Winner Judy Blundell

    ERIC Educational Resources Information Center

    Handler, Daniel

    2009-01-01

    This article presents an interview with National Book Award-winner Judy Blundell. For nearly 20 years, Blundell has toiled in anonymity, turning out more than 100 mysteries, romances, and media tie-ins under various pen names, such as Jude Watson. But in mid-November, the writer-for-hire was suddenly shoved into the spotlight. That's when "What I…

  20. Reform and Change in Inclusive Education: A Tribute to Judy Lupart

    ERIC Educational Resources Information Center

    Deppeler, Joanne

    2012-01-01

    Founding Editor of the journal "Exceptionality Education Canada," Judy Lupart's research, publication, and teaching interests have included an important focus on inclusive education and school transformation. Two of her papers relevant to this work were published in "Exceptionality Education Canada" a decade apart: "Toward a unified system of…

  1. Life Writing Lite: Judy Garland and Reparative Rhetorics of Celebrity Life Writing

    ERIC Educational Resources Information Center

    Janangelo, Joseph

    2010-01-01

    This essay offers a rhetorical reading of entertainer Judy Garland's early life writing projects. The author focuses on two open letters Garland published in 1950, in which she talks to the public and press to let them know "the truth" ("Open") about her life and how much her audience means to her. As a troubled celebrity, Garland had for years…

  2. Look What They've Done to Judy Blume!: The "Basalization" of Children's Literature.

    ERIC Educational Resources Information Center

    Goodman, Kenneth S.

    1988-01-01

    Uses one basalized revision of Judy Blume's "The One in the Middle is the Green Kangaroo" to illustrate how publishers change literature to fit their self-imposed constraints. Criticizes publishers' emphasis on learning words and skills, which causes them to fracture and narrow language, and results in adapted and synthetic texts instead of…

  3. VIEW WEST, SOUTH PENN POWERHOUSE, (FROM LEFT) BLEEDER SHED, ENGINE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW WEST, SOUTH PENN POWERHOUSE, (FROM LEFT) BLEEDER SHED, ENGINE HOUSE, BELT SHED, ECCENTRIC HOUSE. - South Penn Oil Company, G. M. Mead Lot 492 Lease, Morrison Run Field, Clarendon, Warren County, PA

  4. Searching for Judy: How small mysteries affect narrative processes and memory

    PubMed Central

    Love, Jessica; McKoon, Gail; Gerrig, Richard J.

    2010-01-01

    Current theories of text processing say little about how author’s narrative choices, including the introduction of small mysteries, can affect readers’ narrative experiences. Gerrig, Love, and McKoon (2009) provided evidence that one type of small mystery—a character introduced without information linking him or her to the story—affects readers’ moment-by-moment processing. For that project, participants read stories that introduced characters by proper name alone (e.g., Judy) or with information connecting the character to the rest of the story (e.g., our principal Judy). In an on-line recognition probe task, responses to the character’s name three lines after his or her introduction were faster when the character had not been introduced with connecting information, suggesting that the character remained accessible awaiting resolution. In the four experiments in this paper, we extended our theoretical analysis of small mysteries. In Experiments 1 and 2, we found evidence that trait information (e.g., daredevil Judy) is not sufficient to connect a character to a text. In Experiments 3 and 4, we provide evidence that the moment-by-moment processing effects of such small mysteries also affect readers’ memory for the stories. We interpret the results in terms of Kintsch’s Construction-Integration model (1988) of discourse processing. PMID:20438273

  5. Searching for Judy: how small mysteries affect narrative processes and memory.

    PubMed

    Love, Jessica; McKoon, Gail; Gerrig, Richard J

    2010-05-01

    Current theories of text processing say little about how authors' narrative choices, including the introduction of small mysteries, can affect readers' narrative experiences. Gerrig, Love, and McKoon (2009) provided evidence that 1 type of small mystery-a character introduced without information linking him or her to the story-affects readers' moment-by-moment processing. For that project, participants read stories that introduced characters by proper name alone (e.g., "Judy") or with information connecting the character to the rest of the story (e.g., "our principal Judy"). In an online recognition probe task, responses to the character's name 3 lines after his or her introduction were faster when the character had not been introduced with connecting information, suggesting that the character remained accessible awaiting resolution. In the 4 experiments in this article, we extend our theoretical analysis of small mysteries. In Experiments 1 and 2, we found evidence that trait information (e.g., "daredevil Judy") is not sufficient to connect a character to a text. In Experiments 3 and 4, we found evidence that the moment-by-moment processing effects of such small mysteries also affect readers' memory for the stories. We interpret the results in terms of Kintsch's (1988) construction-integration model of discourse processing. PMID:20438273

  6. Penn State's Visual Image User Study

    ERIC Educational Resources Information Center

    Pisciotta, Henry A.; Dooris, Michael J.; Frost, James; Halm, Michael

    2005-01-01

    The Visual Image User Study (VIUS), an extensive needs assessment project at Penn State University, describes academic users of pictures and their perceptions. These findings outline the potential market for digital images and list the likely determinates of whether or not a system will be used. They also explain some key user requirements for…

  7. Penn State researches acid mine drainage

    SciTech Connect

    Not Available

    1984-08-27

    A brief news item reports that work is being carried out at Penn State University on the effectiveness of sphagnum moss and other marsh-type plants in removing iron from acid mine water. A sphagnum moss bog has been established in a greenhouse at the University and field work is also being undertaken in a natural environment in Clearfield County.

  8. Understanding Art Testing: Past Influences, Norman C. Meier's Contributions, Present Concerns, and Future Possibilities.

    ERIC Educational Resources Information Center

    Clark, Gilbert; And Others

    This collection of 10 papers focuses on art testing and Norman C. Meier's role in this area of study. The titles written by Gilbert Clark are: (1) "Early Inquiry, Research, and Testing of Children's Art Abilities"; (2) "Norman C. Meier: A Critique of His Tests and Research"; and (3) "Recent Inquiry and Testing of Children's Art Abilities." The…

  9. Voicing Gay Women's Liberation: Judy Grahn and the Shaping of Lesbian Feminism.

    PubMed

    Rio, Chelsea Del

    2015-01-01

    A closer look at the rich world of California feminisms demonstrates how Judy Grahn served as a central figure in bay area feminism, working to establish and support lesbian activist organizations, feminist publications, women's cultural events, and more. Two of Grahn's early political writings consider how lesbians sat at the nexus of homophobia and sexism. These writings demonstrate the formative role played by San Francisco lesbians in reframing ideas about "women-loving women" and the intersections of gender and sexuality in creating the oppressions faced by all women. PMID:26075688

  10. How To Be a Young Member of the Middle Class: Socialization in the Novels of Judy Blume.

    ERIC Educational Resources Information Center

    Litton, Joyce A.

    The widespread popularity of the young adult novels of Judy Blume makes them important factors in the socialization process. Almost all of the characters in her books are members of the middle or upper-middle class, and with the exception of some of the characters in 4 of her 15 novels, all are white. Thus, Blume is teaching youth how to be…

  11. Penn Macy Initiative To Advance Academic Nursing Practice.

    ERIC Educational Resources Information Center

    Lang, Norma M.; Evans, Lois K.; Swan, Beth Ann

    2002-01-01

    The Penn School of Nursing and the Macy Foundation established a comprehensive institute and technical assistance program to help nursing schools advance academic nursing practice. The Penn School consulted with 21 participating schools, providing institutes, conferences, a listserv and a web-based knowledge center focused on integrating research,…

  12. Judi Dench's age-inappropriateness and the role of M: challenging normative temporality.

    PubMed

    Krainitzki, Eva

    2014-04-01

    This article approaches Judi Dench's role as M in the long-running James Bond series from a gender and ageing studies' perspective and explores this character's subversion of normative concepts of gender and temporality. Based on the assumption that cultural narratives shape our understanding of ageing, it examines how M disrupts prescribed age- and gender roles, presenting an alternative within films which otherwise perpetuate normative notions of a sexualised, youthful femininity. It focusses on Dench's return as M in Casino Royale (2006), as an instance of anachronism (Russo, 1999), subverting viewers' expectation of linear timelines and examines M's challenge of normative age-appropriateness in Skyfall (2012). Despite M's portrayal as a more vulnerable female character in the latter, this article presents her character as an alternative to traditional portrayals of older women on screen. PMID:24655671

  13. Penn State Radar Systems: Implementation and Observations

    NASA Astrophysics Data System (ADS)

    Urbina, J. V.; Seal, R.; Sorbello, R.; Kuyeng, K.; Dyrud, L. P.

    2014-12-01

    Software Defined Radio/Radar (SDR) platforms have become increasingly popular as researchers, hobbyists, and military seek more efficient and cost-effective means for radar construction and operation. SDR platforms, by definition, utilize a software-based interface for configuration in contrast to traditional, hard-wired platforms. In an effort to provide new and improved radar sensing capabilities, Penn State has been developing advanced instruments and technologies for future radars, with primary objectives of making such instruments more capable, portable, and more cost effective. This paper will describe the design and implementation of two low-cost radar systems and their deployment in ionospheric research at both low and mid-latitudes. One radar has been installed near Penn State campus, University Park, Pennsylvania (77.97°W, 40.70°N), to make continuous meteor observations and mid-latitude plasma irregularities. The second radar is being installed in Huancayo (12.05°S, -75.33°E), Peru, which is capable of detecting E and F region plasma irregularities as well as meteor reflections. In this paper, we examine and compare the diurnal and seasonal variability of specular, non- specular, and head-echoes collected with these two new radar systems and discuss sampling biases of each meteor observation technique. We report our current efforts to validate and calibrate these radar systems with other VHF radars such as Jicamarca and SOUSY. We also present the general characteristics of continuous measurements of E-region and F-region coherent echoes using these modern radar systems and compare them with coherent radar events observed at other geographic mid-latitude radar stations.

  14. 7. VIEW OF THREE BOATHOUSES FROM 'PENN AC ROWING ASSN' ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. VIEW OF THREE BOATHOUSES FROM 'PENN AC ROWING ASSN' TO NORTH END OF 'VESPER,' LOOKING EAST FROM WEST BANK OF SCHUYLKILL RIVER - Boathouse Row, East River Drive, Philadelphia, Philadelphia County, PA

  15. 8. VIEW OF THREE BOATHOUSES FROM SOUTHERN END OF 'PENN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. VIEW OF THREE BOATHOUSES FROM SOUTHERN END OF 'PENN AC ROWING ASSN' TO 'VESPER' RIVER FACADE, LOOKING EAST FROM WEST BANK OF SCHUYLKILL RIVER - Boathouse Row, East River Drive, Philadelphia, Philadelphia County, PA

  16. The Engineering Science Curriculum At Penn State

    NASA Astrophysics Data System (ADS)

    Thompson, William

    1997-03-01

    The Engineering Science major at Penn State is an interdisciplinary program of study for academically gifted students that features both breadth and depth exposure to the engineering sciences. It is the honors curriculum in the College of Engineering. During the junior year of this program, students study courses selected from a broad range of the engineering sciences such as solid and fluid mechanics (11 credits total during the four years), thermodynamics and heat transfer (6 credits), electrical sciences (10 credits), materials science (6 credits), and applied mathematics and computer science (30 credits). These courses stress the basic principles underlying engineering analysis and synthesis as well as the transferability of engineering concepts from one discipline to another. Seniors then undertake a seven credit capstone design project which they support with four three-credit technical electives. Students work one-on-one with a faculty member on this capstone design project. Because this faculty member can be in any engineering department, these senior projects cover an enormous range of topics. However, because a large number of the faculty of the Engineering Science department (officially known as the Engineering Science and Mechanics department) have an interest in engineered materials (e.g., composites, sensors, powdered materials, thin films, video displays, MEMS, smart materials, electronic devices) many of the senior projects, as well as many of the graduate theses, involve materials design, fabrication, testing, utilization, or corrosion prevention. Some of the current projects and facilities of the department will be highlighted in this talk.

  17. The Penn State - Torun Planet Search

    NASA Astrophysics Data System (ADS)

    Niedzielski, Andrzej; Wolszczan, A.

    2011-09-01

    The PennState - Torun Planet Search (PTPS) is devoted to search and detailed characterization of planetary system around intermediate-mass stars. These stars, due to their high effective temperature are not accessible to the radial velocity (RV) technique during the Main Sequence (MS) evolution. In principle one can look for planetary-mass companions to such stars using other methods (direct imaging, transits) instead. However, the most efficient way to detect and study planets around such objects is to apply the RV technique when they leave the MS and moving toward the giant branch lower effective temperatures and rotation velocities to allow for precise RV measurements. Within PTPS precise radial velocities (RV) of approx.1000 targets are being obtained from spectra continuously gathered with the Hobby-Eberly Telescope and its High Resolution Spectrograph. The project resulted in discovery of planetary or brown dwarf mass companions to 5 stars. Recently 7 new systems were found, mainly around K giants (Gettel et al. in preparation, Nowak et al. in preparation). In parallel to the RV survey the sample properties are studied in detail. Here we present current status and forthcoming results of the project. Detailed description of the samples (red clump giants, sub-giants and giants, evolved dwarfs) including mass, radius, metallicity and age distributions of target stars will be presented. Since complete description of planetary system hosts requires also information on their rotation velocities and abundances (including lithium abundance) we will presented them as well. As we collected multiple RV observations for all our stars and completed a detailed cross-correlation study we will also discuss binary contamination and present preliminary results on frequency of planetary companion candidates in all 3 samples. We acknowledge the financial support from the Polish Ministry of Science and Higher Education through grants N203 510938 (AN) and from NASA grant NNX09AB36

  18. PENN neurodegenerative disease research - in the spirit of Benjamin Franklin.

    PubMed

    Trojanowski, John Q

    2008-01-01

    Benjamin Franklin (1706-1790) was entrepreneur, statesman, supporter of the public good as well as inventor, and his most significant invention was the University of Pennsylvania (PENN). Franklin outlined his plans for a college providing practical and classical instruction to prepare youth for real-world pursuits in his 'Proposals Relating to the Education of Youth in Pensilvania' (1749), and Franklin's spirit of learning to serve society guides PENN to the present day. This is evidenced by the series of articles in this special issue of Neurosignals, describing research conducted by seasoned and newly recruited PENN faculty, addressing consequences of the longevity revolution which defines our epoch at the dawn of this millennium. While aging affects all organ systems, the nervous system is most critical to successful aging. Thus, the articles in this special issue of Neurosignals focus on research at PENN that is designed to prevent or ameliorate aging-related neurodegenerative disorders such as Alzheimer's and Parkinson's disease, amyotrophic lateral sclerosis and frontotemporal dementia. This research could enhance our chances of aging successfully in the continuing longevity revolution, and the essay here provides context and background on this research. PMID:18097154

  19. Economic Development in Challenging Times: The Penn State Outreach Response

    ERIC Educational Resources Information Center

    Smutz, Wayne; Weidemann, Craig D.

    2008-01-01

    From its inception, Penn State has played a role in Pennsylvania's economy. As a land-grant university, it has functioned as a change agent, transferring research and knowledge to increase farm yields, encouraging business and "the mechanic arts," and transmitting technology to the general population. While the university still does those things…

  20. 78 FR 53184 - Land Release for Penn Yan Airport

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-28

    ... Federal Aviation Administration Land Release for Penn Yan Airport AGENCY: Federal Aviation Administration... consists of 0.069 +/- acres of land and it is currently vacant. The requested release is for the purpose of... boat storage and maintenance facility to be constructed by Land and Sea Properties on airports...

  1. 77 FR 12905 - Land Release for Penn Yan Airport

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-02

    ... Federal Aviation Administration Land Release for Penn Yan Airport AGENCY: Federal Aviation Administration... consists of 10.00 +/- acres of land and it is currently vacant. The requested release is for the purpose of... and maintenance facility by Land and Sea Properties. Documents reflecting the Sponsor's request...

  2. Beyond the Penn State Seminar: A Critique of Curricula.

    ERIC Educational Resources Information Center

    Clark, Gilbert A.

    1984-01-01

    Art curriculum projects influenced by ideas proposed at the Penn State Seminar are described. These include the television series "Images and Things," the textbook series "Art: Meaning, Methods, and Media," the Stanford-Kettering art curriculum, CEMREL's Aesthetic Education Curriculum Program, the SWRL Elementary Art Program, and the Aesthetic Eye…

  3. Science Documentaries at Your Library: Two Penn State Programs

    ERIC Educational Resources Information Center

    Rimland, Emily; Butkovich, Nancy J.; Musser, Linda

    2008-01-01

    Two science branch libraries at Penn State's University Park campus hosted film series centered on scientific documentary films. Although the reasons for starting the series differ, both have been successful in meeting their goals. Patron responses have been favorable, and the series have focused attention on the collections and services offered…

  4. An overview of the Penn State Propulsion Engineering Research Center

    NASA Technical Reports Server (NTRS)

    Merkle, Charles L.

    1991-01-01

    An overview of the Penn State Propulsion Engineering Research Center is presented. The following subject areas are covered: research objectives and long term perspective of the Center; current status and operational philosophy; and brief description of Center projects (combustion, fluid mechanics and heat transfer, materials compatibility, turbomachinery, and advanced propulsion concepts).

  5. Multiple testing procedures based on weighted Kaplan-Meier statistics for right-censored survival data.

    PubMed

    Chi, Yunchan

    2005-01-15

    In clinical trials or drug development studies, researchers are often interested in identifying which treatments or dosages are more effective than the standard one. Recently, several multiple testing procedures based on weighted logrank tests have been proposed to compare several treatments with a control in a one-way layout where survival data are subject to random right-censorship. However, weighted logrank tests are based on ranks, and these tests might not be sensitive to the magnitude of the difference in survival times against a specific alternative. Therefore, it is desirable to develop a more robust and powerful multiple testing procedure. This paper proposes multiple testing procedures based on two-sample weighted Kaplan-Meier statistics, each comparing an individual treatment with the control, to determine which treatments are more effective than the control. The comparative results from a simulation study are presented and the implementation of these methods to the prostate cancer clinical trial and the renal carcinoma tumour study are presented. PMID:15515153

  6. Meier-Gorlin syndrome: growth and secondary sexual development of a microcephalic primordial dwarfism disorder.

    PubMed

    de Munnik, Sonja A; Otten, Barto J; Schoots, Jeroen; Bicknell, Louise S; Aftimos, Salim; Al-Aama, Jumana Y; van Bever, Yolande; Bober, Michael B; Borm, George F; Clayton-Smith, Jill; Deal, Cheri L; Edrees, Alaa Y; Feingold, Murray; Fryer, Alan; van Hagen, Johanna M; Hennekam, Raoul C; Jansweijer, Maaike C E; Johnson, Diana; Kant, Sarina G; Opitz, John M; Ramadevi, A Radha; Reardon, Willie; Ross, Alison; Sarda, Pierre; Schrander-Stumpel, Constance T R M; Sluiter, A Erik; Temple, I Karen; Terhal, Paulien A; Toutain, Annick; Wise, Carol A; Wright, Michael; Skidmore, David L; Samuels, Mark E; Hoefsloot, Lies H; Knoers, Nine V A M; Brunner, Han G; Jackson, Andrew P; Bongers, Ernie M H F

    2012-11-01

    Meier-Gorlin syndrome (MGS) is a rare autosomal recessive disorder characterized by primordial dwarfism, microtia, and patellar aplasia/hypoplasia. Recently, mutations in the ORC1, ORC4, ORC6, CDT1, and CDC6 genes, encoding components of the pre-replication complex, have been identified. This complex is essential for DNA replication and therefore mutations are expected to impair cell proliferation and consequently could globally reduce growth. However, detailed growth characteristics of MGS patients have not been reported, and so this is addressed here through study of 45 MGS patients, the largest cohort worldwide. Here, we report that growth velocity (length) is impaired in MGS during pregnancy and first year of life, but, thereafter, height increases in paralleled normal reference centiles, resulting in a mean adult height of -4.5 standard deviations (SD). Height is dependent on ethnic background and underlying molecular cause, with ORC1 and ORC4 mutations causing more severe short stature and microcephaly. Growth hormone therapy (n = 9) was generally ineffective, though in two patients with significantly reduced IGF1 levels, growth was substantially improved by GH treatment, with 2SD and 3.8 SD improvement in height. Growth parameters for monitoring growth in future MGS patients are provided and as well we highlight that growth is disproportionately affected in certain structures, with growth related minor genital abnormalities (42%) and mammary hypoplasia (100%) frequently present, in addition to established effects on ears and patellar growth. PMID:23023959

  7. A practical divergence measure for survival distributions that can be estimated from Kaplan-Meier curves.

    PubMed

    Cox, Trevor F; Czanner, Gabriela

    2016-06-30

    This paper introduces a new simple divergence measure between two survival distributions. For two groups of patients, the divergence measure between their associated survival distributions is based on the integral of the absolute difference in probabilities that a patient from one group dies at time t and a patient from the other group survives beyond time t and vice versa. In the case of non-crossing hazard functions, the divergence measure is closely linked to the Harrell concordance index, C, the Mann-Whitney test statistic and the area under a receiver operating characteristic curve. The measure can be used in a dynamic way where the divergence between two survival distributions from time zero up to time t is calculated enabling real-time monitoring of treatment differences. The divergence can be found for theoretical survival distributions or can be estimated non-parametrically from survival data using Kaplan-Meier estimates of the survivor functions. The estimator of the divergence is shown to be generally unbiased and approximately normally distributed. For the case of proportional hazards, the constituent parts of the divergence measure can be used to assess the proportional hazards assumption. The use of the divergence measure is illustrated on the survival of pancreatic cancer patients. Copyright © 2016 John Wiley & Sons, Ltd. PMID:26842429

  8. De Novo GMNN Mutations Cause Autosomal-Dominant Primordial Dwarfism Associated with Meier-Gorlin Syndrome

    PubMed Central

    Burrage, Lindsay C.; Charng, Wu-Lin; Eldomery, Mohammad K.; Willer, Jason R.; Davis, Erica E.; Lugtenberg, Dorien; Zhu, Wenmiao; Leduc, Magalie S.; Akdemir, Zeynep C.; Azamian, Mahshid; Zapata, Gladys; Hernandez, Patricia P.; Schoots, Jeroen; de Munnik, Sonja A.; Roepman, Ronald; Pearring, Jillian N.; Jhangiani, Shalini; Katsanis, Nicholas; Vissers, Lisenka E.L.M.; Brunner, Han G.; Beaudet, Arthur L.; Rosenfeld, Jill A.; Muzny, Donna M.; Gibbs, Richard A.; Eng, Christine M.; Xia, Fan; Lalani, Seema R.; Lupski, James R.; Bongers, Ernie M.H.F.; Yang, Yaping

    2015-01-01

    Meier-Gorlin syndrome (MGS) is a genetically heterogeneous primordial dwarfism syndrome known to be caused by biallelic loss-of-function mutations in one of five genes encoding pre-replication complex proteins: ORC1, ORC4, ORC6, CDT1, and CDC6. Mutations in these genes cause disruption of the origin of DNA replication initiation. To date, only an autosomal-recessive inheritance pattern has been described in individuals with this disorder, with a molecular etiology established in about three-fourths of cases. Here, we report three subjects with MGS and de novo heterozygous mutations in the 5′ end of GMNN, encoding the DNA replication inhibitor geminin. We identified two truncating mutations in exon 2 (the 1st coding exon), c.16A>T (p.Lys6∗) and c.35_38delTCAA (p.Ile12Lysfs∗4), and one missense mutation, c.50A>G (p.Lys17Arg), affecting the second-to-last nucleotide of exon 2 and possibly RNA splicing. Geminin is present during the S, G2, and M phases of the cell cycle and is degraded during the metaphase-anaphase transition by the anaphase-promoting complex (APC), which recognizes the destruction box sequence near the 5′ end of the geminin protein. All three GMNN mutations identified alter sites 5′ to residue Met28 of the protein, which is located within the destruction box. We present data supporting a gain-of-function mechanism, in which the GMNN mutations result in proteins lacking the destruction box and hence increased protein stability and prolonged inhibition of replication leading to autosomal-dominant MGS. PMID:26637980

  9. Status Report on the Penn State RBCC Test Program

    NASA Technical Reports Server (NTRS)

    Cramer, J.; Lehman, M.; Pal, S.; Lee, S.-Y.; Santoro, R.; Turner, Jim E. (Technical Monitor)

    2000-01-01

    The status of the RBCC ejector mode research program at Penn State is reviewed. Recent hardware modifications and measurement system improvements are discussed, including the motivation for these changes. Results from a series of tests with a single thruster configuration at a chamber pressure of 200 psia and with an area ratio 3.3 nozzle are presented. These results indicate that the primary (rocket exhaust) and secondary (entrained air) flow streams mix much more rapidly than a previous test series with an area ratio of 6.0 nozzle. Finally, the plans for a test series with a twin thruster configuration are discussed.

  10. Measurement of Trigeminal Neuralgia Pain: Penn Facial Pain Scale.

    PubMed

    Lee, John Y K

    2016-07-01

    Pain is a subjective experience that cannot be directly measured. Therefore, patient-reported outcome is one of the currently accepted methods to capture pain intensity and its impact on activities of daily living. This article focuses on five patient-reported outcomes that have been used to measure trigeminal neuralgia pain-Visual Analog Scale, numeric rating scale, Barrow Neurological Institute Pain Intensity Score, McGill Pain Questionnaire, and Penn Facial Pain Scale. Each scale is evaluated for its practicality, applicability, comprehensiveness, reliability, validity, and sensitivity to measuring trigeminal neuralgia pain. PMID:27324999

  11. Mechanical devices to help in PennHIP examination.

    PubMed

    Ginja, M M D; Llorens-Pena, Maria P; Gonzalo-Orden, J M; Ferreira, A J A

    2007-06-01

    A modified PennHIP procedure (MPP), using specific mechanical holding devices, was used on 70 dogs and compared to the standard PennHIP method (SPM) used on 39 dogs, in terms of technical effectiveness and the mean number of essential individuals within the X-ray room (EIXRR). The data using the Chi-squared test were consistent with the null hypothesis that the technical effectiveness was equal in the groups under investigation (P > 0.05). On the contrary, using the two-sample unpaired t-test the null hypothesis, that the mean EIXRR was equal, was rejected (P < 0.001). The estimated EIXRR was 3.4 +/- 0.7 and 5.7 +/- 1.2 (mean +/- SD) for MPP and SPM, respectively. In conclusion, the MPP needs fewer EIXXR than the SPM and complies with the new recommendations in X-ray protection, which introduce the ALARA (as-low-as-reasonably-achievable) idea. PMID:17555284

  12. 77 FR 35850 - Safety Zone; F/V Deep Sea, Penn Cove, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-15

    ... Homeland Security FR Federal Register NPRM Notice of Proposed Rulemaking A. Regulatory History and... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; F/V Deep Sea, Penn Cove, WA AGENCY: Coast... the Fishing Vessel (F/V) Deep Sea, located in Penn Cove, WA. This action is necessary to ensure...

  13. Recycling at Penn State's Beaver Stadium. "Recycle on the Go" Success Story

    ERIC Educational Resources Information Center

    US Environmental Protection Agency, 2009

    2009-01-01

    With a 13-year-old recycling program, The Pennsylvania State University's (Penn State) Beaver Stadium in the past diverted nearly 30 tons of recyclables per year from local landfills. A new initiative to promote recycling in the stadium's tailgating area has helped Penn State more than triple its old recycling record, collecting 112 tons in 2008.…

  14. 77 FR 44310 - Penn-Ohio Transportation, LLC-Acquisition Exemption-Eastern States Railroad, LLC and Columbiana...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-27

    ..., LLC and Columbiana County Port Authority Penn-Ohio Transportation, LLC (Penn-Ohio), a noncarrier, has... Columbiana County Port Authority (CCPA); (2) receive permanent assignment of ESR's and CCPA's agreements...

  15. Design and performance of HEAD PENN-PET scanner

    SciTech Connect

    Freifelder, R.; Karp, J.S. . Dept. of Radiology); Geagan, M.; Muehllehner, G. )

    1994-08-01

    A new PET scanner for brain imaging (and animals) has been designed with very high sensitivity and spatial resolution. The design is an evolution of the PENN-PET scanner, which uses large position-sensitive NaI(Tl) detectors, with Anger-type positioning logic, and which allows 3-D volume imaging, without septa. The new design is built with a single annular crystal coupled to 180 photomultiplier tubes, and uses local triggering electronics to subdivide the detector into small zones and to determine coincident events within the detector. The axial acceptance angle of [+-] 27 deg, with a field-of-view of 25.6 cm, is larger than any currently operating PET scanner. Performance measurements are presented.

  16. Intratympanic gentamicin treatment 'as needed' for Meniere's disease. Long-term analysis using the Kaplan-Meier method.

    PubMed

    Quaglieri, Silvia; Gatti, Omar; Rebecchi, Elisabetta; Manfrin, Marco; Tinelli, Carmine; Mira, Eugenio; Benazzo, Marco

    2014-06-01

    In recent years, several titration or on-demand protocols using low-dose repeated intratympanic (IT) gentamicin injections have been adopted for the vertigo control in unilateral medical refractory Menière's disease (MD). Because of the frequent recurrence and the need to treat the patients several times, it is difficult to strictly follow the 1995 AAO-HNS criteria to classify the results. The Kaplan-Meier analysis provides an effective and simpler method to address these concerns. We report the results of a long-term study (7 years) on a large population of MD patients (174) treated with on-request low-dose delayed IT gentamicin injections analysed using the Kaplan-Meier survival method. Effective vertigo control was obtained with a single injection in 40.2% of the patients (excellent responders) and with repeated injections (2-9) in 43.7% of the patients (moderate responders). Only six patients (3.5%) needed to be submitted to vestibular neurectomy because of the persistence of vertigo attacks (non-responders). A subgroup of 22 patients (12.6%) reporting a late recurrence of vertigo attacks after an initial vertigo-free interval lasting more than 2 years (short-term responders) were successfully treated with a further cycle of injections. In no cases, we observed significant signs of cochlear or vestibular toxicity. Kaplan-Meier survival analysis provided an excellent method for reporting treatment success or failure in patients followed for variable length of time with our kind of protocol. PMID:23778723

  17. BRIE: The Penn State Biogeochemical Research Initiative for Education

    NASA Astrophysics Data System (ADS)

    Freeman, K. H.; Brantley, S. L.; Brenchley, J.

    2003-12-01

    Few scientists are prepared to address the interdisciplinary challenges of biogeochemical research due to disciplinary differences in vocabulary, technique, and scientific paradigm. Thus scientists and engineers trained in traditional disciplines bring a restricted view to the study of environmental systems, which can limit their ability to exploit new techniques and opportunities for scientific advancement. Although the literature is effusive with enthusiasm for interdisciplinary approaches to biogeochemistry, there remains the basic difficulty of cross-training geological and biological scientists. The NSF-IGERT funded Biogeochemical Research Initiative for Education (BRIE) program at Penn State is specifically designed to break down both disciplinary and institutional barriers and it has fostered cross-disciplinary collaboration and training since 1999. Students and faculty are drawn from environmental engineering, geochemistry, soil science, chemistry and microbiology, and the program is regarded on the Penn State campus as a successful example of how interdisciplinary science can best be promoted. There are currently 23 Ph.D. students funded by the program, with an additional 7 affiliated students. At present, a total of 6 students have completed doctoral degrees, and they have done so within normal timeframes. The program is "discipline-plus," whereby students enroll in traditional disciplinary degree programs, and undertake broad training via 12 credits of graduate coursework in other departments. Students are co-advised by faculty from different disciplines, and engage in interdisciplinary research facilitated by research "credit cards." Funding is available for international research experiences, travel to meetings, and other opportunities for professional development. Students help institutionalize interdisciplinary training by designing and conducting a teaching module that shares their expertise with a class in another department or discipline

  18. Developing a blueprint for cultural competence education at Penn.

    PubMed

    Watts, Rosalyn J; Cuellar, Norma G; O'Sullivan, Ann L

    2008-01-01

    This article describes the structure, process, and outcomes of developing a blueprint for integration of cultural competence education into the curriculum at the University of Pennsylvania, School of Nursing. The overarching framework of Kotter (1995) on leading change and organizational transformation was used as a guide for evaluation of faculty efforts. Within the setting of a research-intensive university, the process consisted of implementing a series of action steps which included appointment of a Director of Diversity Affairs, selection of a Master Teachers Taskforce on Cultural Diversity as catalysts for change; conduction of intensive faculty development programs, dissemination of information about cultural competence education, and use of innovative teaching approaches and student participation in curriculum activities. In addition, a Blueprint for Integration of Cultural Competence in the Curriculum (BICCC) was developed and used as the instrument for faculty surveys for 2 consecutive academic years. Faculty survey findings showed a substantial increase in the number of courses integrating cultural competence content in the programs of study. Successful outcomes of the Penn initiative were due to administrative and faculty support, utilization of a Director of Diversity Affairs, innovative work of the Master Teachers Taskforce on Cultural Diversity, faculty development initiatives, and development of the BICCC as a guiding framework for identifying areas of needed curricular change. PMID:18504026

  19. The future of acoustics distance education at Penn State

    NASA Astrophysics Data System (ADS)

    Brooks, Karen P.; Sparrow, Victor W.; Atchley, Anthony A.

    2005-04-01

    For nearly 20 years Penn State's Graduate Program in Acoustics has offered a graduate distance education program, established in response to Department of Defense needs. Using satellite technology, courses provided synchronous classes incorporating one-way video and two-way audio. Advancements in technology allowed more sophisticated delivery systems to be considered and courses to be offered to employees of industry. Current technology utilizes real time video-streaming and archived lectures to enable individuals anywhere to access course materials. The evolution of technology, expansion of the geographic market and changing needs of the student, among other issues, require a new paradigm. This paradigm must consider issues such as faculty acceptance and questions facing all institutions with regard to blurring the distinction between residence and distance education. Who will be the students? What will be the purpose of education? Will it be to provide professional and/or research degrees? How will the Acoustics Program ensure it remains attractive to all students, while working within the boundaries and constraints of a major research university? This is a look at current practice and issues with an emphasis on those relevant to constructing the Acoustics Programs distance education strategy for the future.

  20. KMWin – A Convenient Tool for Graphical Presentation of Results from Kaplan-Meier Survival Time Analysis

    PubMed Central

    Gross, Arnd; Ziepert, Marita; Scholz, Markus

    2012-01-01

    Background Analysis of clinical studies often necessitates multiple graphical representations of the results. Many professional software packages are available for this purpose. Most packages are either only commercially available or hard to use especially if one aims to generate or customize a huge number of similar graphical outputs. We developed a new, freely available software tool called KMWin (Kaplan-Meier for Windows) facilitating Kaplan-Meier survival time analysis. KMWin is based on the statistical software environment R and provides an easy to use graphical interface. Survival time data can be supplied as SPSS (sav), SAS export (xpt) or text file (dat), which is also a common export format of other applications such as Excel. Figures can directly be exported in any graphical file format supported by R. Results On the basis of a working example, we demonstrate how to use KMWin and present its main functions. We show how to control the interface, customize the graphical output, and analyse survival time data. A number of comparisons are performed between KMWin and SPSS regarding graphical output, statistical output, data management and development. Although the general functionality of SPSS is larger, KMWin comprises a number of features useful for survival time analysis in clinical trials and other applications. These are for example number of cases and number of cases under risk within the figure or provision of a queue system for repetitive analyses of updated data sets. Moreover, major adjustments of graphical settings can be performed easily on a single window. Conclusions We conclude that our tool is well suited and convenient for repetitive analyses of survival time data. It can be used by non-statisticians and provides often used functions as well as functions which are not supplied by standard software packages. The software is routinely applied in several clinical study groups. PMID:22723912

  1. Psychometric Properties of the Penn Computerized Neurocognitive Battery

    PubMed Central

    Moore, Tyler M.; Reise, Steven P.; Gur, Raquel E.; Hakonarson, Hakon; Gur, Ruben C.

    2014-01-01

    Objective The Penn Computerized Neurocognitive Battery (CNB) was designed to measure performance accuracy and speed on specific neurobehavioral domains using tests that were previously validated with functional neuroimaging. A crucial step in determining whether the CNB has attained its objective is to assess its factor structure. The goal of the present study was to evaluate the neuropsychological theory used to construct the CNB by confirming the factor structure of the tests composing it. Method In a large community sample (N = 9138; age range 8-21), we performed a correlated-traits confirmatory factor analysis (CFA) and multiple exploratory factor analyses (EFA’s) on the twelve CNB measures of Efficiency (which combine Accuracy and Speed). To further explore the measures contributing to Efficiency, we then performed EFA’s of the Accuracy and Speed measures separately. Finally, we performed a confirmatory bifactor analysis of the Efficiency scores. All analyses were performed with Mplus using maximum likelihood estimation. Results Results strongly support the a priori theory used to construct the CNB, showing that tests designed to measure executive, episodic memory, complex cognition and social cognition aggregate their loadings within these domains. When Accuracy and Speed were analyzed separately, Accuracy produced three reliable factors: executive and complex cognition, episodic memory and social cognition, while speed produced two factors: tests that require fast responses and those where each item requires deliberation. The interpretability and statistical “Fit” of almost all models described above was acceptable (usually excellent). Conclusions Based on the well powered analysis from these large scale data, the CNB offers an effective means for measuring the integrity of intended neurocognitive domains in about one hour of testing and is thus suitable for large-scale clinical and genomic studies. PMID:25180981

  2. 78 FR 3412 - EnerPenn USA LLC; Supplemental Notice That Initial Market-Based Rate Filing Includes Request for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-16

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission EnerPenn USA LLC; Supplemental Notice That Initial Market-Based Rate Filing...-referenced proceeding, of EnerPenn USA LLC's application for market-based rate authority, with...

  3. The Penn State Mini Medical School: A Prescription for Community Engagement in Health Care Issues and Research

    ERIC Educational Resources Information Center

    Thorndyke, Luanne E.; Bixler, Bonnie J.; Carubia, Josephine M.

    2004-01-01

    The Penn State Mini Medical School is a high-impact community engagement program created and led by the Office of Continuing Education at the Penn State College of Medicine. The broad goals of the program are to respond to the general public's intense desire for health and medical information, to educate the community about biomedical science and…

  4. EVIDENCE FOR METAL ATTENUATION IN ACID MINE WATER BY SULFATE REDUCTION, PENN MINE, CALAVERAS COUNTY, CALIFORNIA

    EPA Science Inventory

    The Penn Mine in Calaveras County, California, produced Cu from massive sulfide ores from 1861 to 1953. Mine wastes were removed to a landfill during the late 1990s, improving surface-water quality, but deep mine workings were not remediated and contain metalliferous water with p...

  5. Keeping the Horse before the Cart: Penn State's E-Portfolio Initiative

    ERIC Educational Resources Information Center

    Johnson, Glenn; DiBiase, David

    2004-01-01

    The Pennsylvania State University (Penn State) has actively promoted e-portfolio use among undergraduate students at its University Park campus since May 2002. The primary objective is to foster consensus among faculty members and students about the nature and potential benefits of portfolio practice. Guiding this effort is the vision of a…

  6. The sharing of the Penn State Breazeale Reactor with other educational institutions

    SciTech Connect

    1995-12-31

    The Penn State Radiation Science and Engineering Center (RSEC) integrates the Breazeale Reactor and its affiliated laboratories and facilities on the University Park Campus. Penn State has the only nuclear reactor in Pennsylvania dedicated to research and education. Its faculty have pioneered industrial and research applications of radiation and radioisotopes. In addition, the center and its affiliated faculty have access to the multidisciplinary resources and expertise available within Penn State, one of the nation`s leading research universities. The goals of the Penn State Radiation Science and Engineering Center are to: incorporate radiation science and engineering services and facilities into a cohesive infrastructure; provide state-of-the-art academic instruction and laboratory experiences; provide facilities and assistance for academic research; provide technical, engineering, and other support services to RSEC users; generate new techniques, applications, and services for researchers in diverse disciplines; and serve the needs of academia and industry through RSEC services, faculty affiliations, and facilities that are not readily available elsewhere.

  7. Evaluation of the Penn Macy Initiative To Advance Academic Nursing Practice.

    ERIC Educational Resources Information Center

    Evans, Lois K.; Swan, Beth Ann; Lang, Norma E.

    2003-01-01

    In the Penn Macy Initiative, 21 nursing schools participated in summer institutes and follow-up consultations to refine practice. Evaluation data from participants' daily and postinstitute feedback, institutional self-evaluations, and comparison of school accomplishments identified critical indicators of progress in academic practice. A key…

  8. Preventing Adolescents' Externalizing and Internalizing Symptoms: Effects of the Penn Resiliency Program

    ERIC Educational Resources Information Center

    Cutuli, J. J.; Gillham, Jane E.; Chaplin, Tara M.; Reivich, Karen J.; Seligman, Martin E. P.; Gallop, Robert J.; Abenavoli, Rachel M.; Freres, Derek R.

    2013-01-01

    This study reports secondary outcome analyses from a past study of the Penn Resiliency Program (PRP), a cognitive-behavioral depression prevention program for middle-school aged children. Middle school students (N = 697) were randomly assigned to PRP, PEP (an alternate intervention), or control conditions. Gillham et al., (2007) reported analyses…

  9. The Blended Librarian: John D. Shankl Center for Learning Technologies, Penn State Berks Lehigh Valley College

    ERIC Educational Resources Information Center

    Library Journal, 2005

    2005-01-01

    Early in his library career, John Shank realized that not only were students choosing Internet resources over library, resources, but Faculty members were, too. Shank is now widely recognized as a librarian who's likely to change that. In his current positions as instructional design librarian at Penn State Berks--Lehigh Valley College and…

  10. A Meta-Analytic Review of the Penn Resiliency Program's Effect on Depressive Symptoms

    ERIC Educational Resources Information Center

    Brunwasser, Steven M.; Gillham, Jane E.; Kim, Eric S.

    2009-01-01

    The purpose of this review was to evaluate whether the Penn Resiliency Program (PRP), a group cognitive-behavioral intervention, is effective in targeting depressive symptoms in youths. We identified 17 controlled evaluations of PRP (N = 2,498) in which depressive symptoms had been measured via an online search of PsycInfo, Medline, ERIC, and…

  11. Databases by the Dozen: The Challenge of Multiple Interfaces at Penn State.

    ERIC Educational Resources Information Center

    Friend, Linda

    1994-01-01

    Describes the alternatives used by the Penn State University libraries to respond to the challenge of providing access to the many different kinds of databases. Approaches include development of a generic interface based on the Z39.50 protocol; staff support, including instruction, reliable documentation, and staff involvement; and better user…

  12. The Penn state lunar lion: A university mission to explore the moon

    NASA Astrophysics Data System (ADS)

    Paul, Michael V.; Spencer, David B.; Lego, Sara E.; Muncks, John P.

    2014-03-01

    The Penn State Lunar Lion Team plans to send a robotic explorer to the surface of the Moon and, by applying 30 years of technological advancements, win the Google Lunar X Prize. The Google Lunar X Prize aims to showcase the ability of the growing private space industry by having teams pursue the goal of becoming the first private entity to land a spacecraft on another body in the solar system. Through the Team's pursuit of this Prize, Penn State will establish itself as a leader in space exploration. The Lunar Lion Team will win this Prize through the collaboration of faculty and students from multiple disciplines, and the engineering and technical staff at the Penn State Applied Research Lab, as well as strategic collaborations with industry partners. The diversity of technical disciplines required to build a system that can land on the Moon can be found at Penn State. This multidisciplinary project will be not only a means for bringing together personnel from around the University, but also a way to attract faculty and students to these fields. The baseline concept for the Lunar Lion will strictly follow the requirements of the Grand Prize and the Grand Prize only, leading to the simplest possible system for the mission. By achieving the Grand Prize, Penn State will have accomplished what once took the large-scale effort of NASA's early robotic lunar landers or the USSR's space program. While the Bonus Prizes are noteworthy, ensuring their accomplishment will add development and operational risk to the flight system that could jeopardize the Team's ability to win the Grand Prize. The Team will build the simplest spacecraft, with the fewest number of systems and components. This philosophy will shorten the development timeline and result in a robust flight system that is of minimum cost. Wherever possible, the Team will use commercially available products to satisfy the needs of the system. The work of the Team will be efficient systems integration, careful

  13. Administration of an insulin powder to the lungs of cynomolgus monkeys using a Penn Century insufflator.

    PubMed

    Grainger, C I; Alcock, R; Gard, T G; Quirk, A V; van Amerongen, G; de Swart, R L; Hardy, J G

    2004-01-28

    A powder formulation of live-attenuated measles vaccine is being developed for administration to the lungs. The safety and efficacy of the powder will be assessed by insufflation into cynomolgus monkeys. A Penn Century insufflator has been evaluated for powder dosing to the monkeys using an insulin formulation having similar physicochemical characteristics to the vaccine powder. Insulin pharmacokinetics were compared following dosing by powder insufflation, solution instillation into the trachea and subcutaneous injection. The insulin dosed to the lungs and trachea was more rapidly absorbed than that administered subcutaneously. Insulin bioavailability was greater from the inhaled powder than from the instilled solution. The findings confirm that the Penn Century device is suitable for vaccine powder dosing to the deep lung. PMID:14706262

  14. PennTwins: A Population-Based Cohort for Twin Studies

    PubMed Central

    Coccaro, Emil F.; Jacobson, Kristen C.

    2014-01-01

    The current article describes the creation and composition of the PennTwins Cohort and provides details on the demographic characteristics of the sample. The PennTwins Cohort was developed using a population-based method of ascertainment and currently has 9401 28- to 47-year-old twins, including 2225 confirmed twin pairs and 4951 twins whose co-twins have not yet registered. Zygosity data have been used to identify 919 monozygotic, 634 same-sex dizygotic, and 445 opposite-sex dizygotic pairs. GeoCode data on gender, age, and certain demographic characteristics were obtained for the addresses of all twins who were mailed invitations to be part of the cohort. Analysis of the available data show only very small differences between twins who are currently part of the PennTwins Cohort and potential twins who either did not respond to recruitment or who could not be located. Similarly, only very small demographic differences exist between twins from complete pairs and twins whose co-twins are not yet registered, and there are no differences across zygosity. Thus, despite a relatively low overall response rate (12% of all twins born in Pennsylvania from 1959–1978), there is no evidence that the sample differs in any meaningful respect from the larger population. PMID:17254443

  15. Concentration and dispersal of a Pseudo-nitzschia bloom in Penn Cove, Washington, USA.

    PubMed

    Trainer, V L; Adams, N G; Bill, B D; Anulacion, B F; Wekell, J C

    1998-01-01

    A bloom of the pennate diatom Pseudo-nitzschia, several species of which are associated with the production of the potent excitotoxin domoic acid, was observed in a Puget Sound, Washington embayment in July and August of 1997. Penn Cove, which receives nutrients from the nearby Skagit River and abundant sunshine during summer months due to its location in the rain shadow of the Olympic Mountains, is the home of a commercial mussel farm which supplies shellfish to many coastal areas of the USA. Levels of domoic acid in mussels increased to 3 ppm on 6 and 10 July, corresponding to the observation of a brown algal bloom in Penn Cove. Four species of Pseudo-nitzschia (P. pungens, P. multiseries, P. australis, and P. pseudodelicatissima) were present in our samples from the cove, corresponding to levels of domoic acid in seawater ranging from 0.1-0.8 mirog l(-1) as measured by a receptor binding assay. The highest Pseudo-nitzschia concentration during the time of our sampling was 13 million cells per liter on 28 July. The bloom of Pseudo-nitzschia occurred after a period of strong discharge from the Skagit River and rain accompanied by elevated south and southeasterly winds. Stratification of the cove, providing optimal bloom conditions, was facilitated by weak winds, sunshine, and a freshwater lens at the mouth of the cove. The position of the Pseudo-nitzschia bloom was influenced by buoyancy fronts caused by exchange of water within the cove with that of Saratoga Passage. The decay of this bloom in Penn Cove was accompanied by decreasing nitrate levels at all measured depths. These and future observations aid in the development of a model for prediction of toxic bloom events in the shallow embayments of Puget Sound. PMID:10223627

  16. Penn State Multi-Discipline Tribology Group and Energy Institute Studies.

    SciTech Connect

    Perez, Joseph

    2001-08-05

    This presentation is a summary of the current research activities on fuels and lubricants in the Multi-discipline Tribology group and the engine test group in the Combustion Laboratory of the Pennsylvania State University. The progress areas discussed in this summary include those found in Table 1. Table 1. RESEARCH AREAS: Diesel Engine Emission Reduction; Oxygenated Fuels; Improved Friction Fuels; Vegetable Oil Lubricants; Extended Drain Lubricants; Effect of Chemical Structure on Friction and Wear. The research is of interest either directly or indirectly to the goal of this workshop, diesel engine emissions reduction. The current projects at Penn State in the areas listed above will be discussed.

  17. Viewgraph description of Penn State's Propulsion Engineering Research Center: Activity highlights and future plans

    NASA Technical Reports Server (NTRS)

    Merkle, Charles L.

    1991-01-01

    Viewgraphs are presented that describe the progress and status of Penn State's Propulsion Engineering Research Center. The Center was established in Jul. 1988 by a grant from NASA's University Space Engineering Research Centers Program. After two and one-half years of operation, some 16 faculty are participating, and the Center is supporting 39 graduate students plus 18 undergraduates. In reviewing the Center's status, long-term plans and goals are reviewed and then the present status of the Center and the highlights and accomplishments of the past year are summarized. An overview of plans for the upcoming year are presented.

  18. A Meier-Gorlin syndrome mutation in a conserved C-terminal helix of Orc6 impedes origin recognition complex formation

    PubMed Central

    Bleichert, Franziska; Balasov, Maxim; Chesnokov, Igor; Nogales, Eva; Botchan, Michael R; Berger, James M

    2013-01-01

    In eukaryotes, DNA replication requires the origin recognition complex (ORC), a six-subunit assembly that promotes replisome formation on chromosomal origins. Despite extant homology between certain subunits, the degree of structural and organizational overlap between budding yeast and metazoan ORC has been unclear. Using 3D electron microscopy, we determined the subunit organization of metazoan ORC, revealing that it adopts a global architecture very similar to the budding yeast complex. Bioinformatic analysis extends this conservation to Orc6, a subunit of somewhat enigmatic function. Unexpectedly, a mutation in the Orc6 C-terminus linked to Meier-Gorlin syndrome, a dwarfism disorder, impedes proper recruitment of Orc6 into ORC; biochemical studies reveal that this region of Orc6 associates with a previously uncharacterized domain of Orc3 and is required for ORC function and MCM2–7 loading in vivo. Together, our results suggest that Meier-Gorlin syndrome mutations in Orc6 impair the formation of ORC hexamers, interfering with appropriate ORC functions. DOI: http://dx.doi.org/10.7554/eLife.00882.001 PMID:24137536

  19. Results From Penn State's Interactive, On-line, Scifi Version Of Astro 001

    NASA Astrophysics Data System (ADS)

    Palma, Christopher; Charlton, J. C.; Herrmann, K.; Narayanan, A.; Tr'Ehnl, N.

    2007-12-01

    We present results from a new, fully on-line astronomy course for undergraduate non-science majors at Penn State that was offered for the first time in Spring 2007 to 422 enrolled students. The entire course content is conveyed through an interactive story, capitalizing on the many multimedia astronomy resources publicly available on the Internet. The four units of the course (Basic Astronomy and the Nighttime Sky, Our Solar System, Stars and the Milky Way Galaxy, and Extragalactic Astronomy and Cosmology) deliver the same content as a traditional Astro 001 course. Each unit follows the educational adventure of a different fictional Astro 001 student who has been "abducted" by aliens. The four units are united by a character, the Riddler, who poses riddles about various aspects of astronomy, and whose identity and purpose is revealed gradually as a reward for completion of various subtopics. The initial Spring offering of the course was entirely web-based except for traditional evening in-class exams. We were very successful: it was popular with the students, the exam grades were about 10% higher than usual, and enrollments in Fall 2007 (more than 700 students) and Spring 2008 (almost 200 pre-enrolled to date) are strong. Future plans are underway to broaden the audience to students attending other Penn State campuses and perhaps to adapt the course for presentation as an astronomy unit to middle or high school students. We gratefully acknowledge funding from STScI IDEAS grant HST-ED-90284-01-A

  20. Penn State Worry Questionnaire - 10: A new tool for measurement-based care.

    PubMed

    Yao, Beier; Sripada, Rebecca K; Klumpp, Heide; Abelson, James L; Muzik, Maria; Zhao, Zhuo; Rosenblum, Katherine; Briggs, Hedieh; Kaston, Michelle; Warren, Ricks

    2016-05-30

    The Penn State Worry Questionnaire - Past Week (PSWQ-PW) is an adaptation of the widely used Penn State Worry Questionnaire, measuring pathological worry weekly. However, it contains problematic negatively worded items and has not been validated in a large sample yet. To meet the needs of measurement-based care (MBC), we developed a shortened version (PSWQ-10) based on the PSWQ-PW, retaining only positively worded items, and examined its psychometric properties and clinical utility. Patients with Generalized Anxiety Disorder (GAD), Major Depressive Disorder (MDD), and other anxiety disorders completed the PSWQ-10 and other instruments during routine evaluation in an academic anxiety clinic. A second cohort from a perinatal clinic was evaluated similarly. The PSWQ-10 displayed excellent internal consistency, convergent and discriminant validity, and criterion group validity. Patients with GAD scored significantly higher than those with other anxiety disorders but did not differ from those with MDD. The PSWQ-10 showed sensitivity to change over time and demonstrated excellent psychometric properties in the perinatal population. The PSWQ-10 is a reliable, valid, efficient, and straightforward worry-focused instrument that can be readily used in MBC and help clinicians objectively measure worry as a treatment outcome in broad clinical populations. PMID:27137962

  1. School-Based Prevention of Depressive Symptoms: A Randomized Controlled Study of the Effectiveness and Specificity of the Penn Resiliency Program

    ERIC Educational Resources Information Center

    Gillham, Jane E.; Reivich, Karen J.; Freres, Derek R.; Chaplin, Tara M.; Shatte, Andrew J.; Samuels, Barbra; Elkon, Andrea G. L.; Litzinger, Samantha; Lascher, Marisa; Gallop, Robert; Seligman, Martin E. P.

    2007-01-01

    The authors investigated the effectiveness and specificity of the Penn Resiliency Program (PRP; J. E. Gillham, L. H. Jaycox, K. J. Reivich, M. E. P. Seligman, & T. Silver, 1990), a cognitive-behavioral depression prevention program. Children (N = 697) from 3 middle schools were randomly assigned to PRP, Control (CON), or the Penn Enhancement …

  2. Characterization of the variable cow's age at last calving as a measurement of longevity by using the Kaplan-Meier estimator and the Cox model.

    PubMed

    Caetano, S L; Rosa, G J M; Savegnago, R P; Ramos, S B; Bezerra, L A F; Lôbo, R B; de Paz, C C P; Munari, D P

    2013-04-01

    In most studies on beef cattle longevity, only the cows reaching a given number of calvings by a specific age are considered in the analyses. With the aim of evaluating all cows with productive life in herds, taking into consideration the different forms of management on each farm, it was proposed to measure cow longevity from age at last calving (ALC), that is, the most recent calving registered in the files. The objective was to characterize this trait in order to study the longevity of Nellore cattle, using the Kaplan-Meier estimators and the Cox model. The covariables and class effects considered in the models were age at first calving (AFC), year and season of birth of the cow and farm. The variable studied (ALC) was classified as presenting complete information (uncensored = 1) or incomplete information (censored = 0), using the criterion of the difference between the date of each cow's last calving and the date of the latest calving at each farm. If this difference was >36 months, the cow was considered to have failed. If not, this cow was censored, thus indicating that future calving remained possible for this cow. The records of 11 791 animals from 22 farms within the Nellore Breed Genetic Improvement Program ('Nellore Brazil') were used. In the estimation process using the Kaplan-Meier model, the variable of AFC was classified into three age groups. In individual analyses, the log-rank test and the Wilcoxon test in the Kaplan-Meier model showed that all covariables and class effects had significant effects (P < 0.05) on ALC. In the analysis considering all covariables and class effects, using the Wald test in the Cox model, only the season of birth of the cow was not significant for ALC (P > 0.05). This analysis indicated that each month added to AFC diminished the risk of the cow's failure in the herd by 2%. Nonetheless, this does not imply that animals with younger AFC had less profitability. Cows with greater numbers of calvings were more precocious

  3. Meier-Gorlin syndrome and Wolf-Hirschhorn syndrome: two developmental disorders highlighting the importance of efficient DNA replication for normal development and neurogenesis.

    PubMed

    Kerzendorfer, Claudia; Colnaghi, Rita; Abramowicz, Iga; Carpenter, Gillian; O'Driscoll, Mark

    2013-08-01

    Microcephaly represents one of the most obvious clinical manifestations of impaired neurogenesis. Defects in the DNA damage response, in DNA repair, and structural abnormalities in centrosomes, centrioles and the spindle microtubule network have all been demonstrated to cause microcephaly in humans. Work describing novel functional defects in cell lines from individuals with either Meier-Gorlin syndrome or Wolf-Hirschhorn syndrome highlight the significance of optimal DNA replication and S phase progression for normal human development, including neurogenesis. These findings illustrate how different primary defects in processes impacting upon DNA replication potentially influence similar phenotypic outcomes, including growth retardation and microcephaly. Herein, we will describe the nature of the S phase defects uncovered for each of these conditions and highlight some of the overlapping cellular features. PMID:23706772

  4. Mutations in CDC45, Encoding an Essential Component of the Pre-initiation Complex, Cause Meier-Gorlin Syndrome and Craniosynostosis.

    PubMed

    Fenwick, Aimee L; Kliszczak, Maciej; Cooper, Fay; Murray, Jennie; Sanchez-Pulido, Luis; Twigg, Stephen R F; Goriely, Anne; McGowan, Simon J; Miller, Kerry A; Taylor, Indira B; Logan, Clare; Bozdogan, Sevcan; Danda, Sumita; Dixon, Joanne; Elsayed, Solaf M; Elsobky, Ezzat; Gardham, Alice; Hoffer, Mariette J V; Koopmans, Marije; McDonald-McGinn, Donna M; Santen, Gijs W E; Savarirayan, Ravi; de Silva, Deepthi; Vanakker, Olivier; Wall, Steven A; Wilson, Louise C; Yuregir, Ozge Ozalp; Zackai, Elaine H; Ponting, Chris P; Jackson, Andrew P; Wilkie, Andrew O M; Niedzwiedz, Wojciech; Bicknell, Louise S

    2016-07-01

    DNA replication precisely duplicates the genome to ensure stable inheritance of genetic information. Impaired licensing of origins of replication during the G1 phase of the cell cycle has been implicated in Meier-Gorlin syndrome (MGS), a disorder defined by the triad of short stature, microtia, and a/hypoplastic patellae. Biallelic partial loss-of-function mutations in multiple components of the pre-replication complex (preRC; ORC1, ORC4, ORC6, CDT1, or CDC6) as well as de novo stabilizing mutations in the licensing inhibitor, GMNN, cause MGS. Here we report the identification of mutations in CDC45 in 15 affected individuals from 12 families with MGS and/or craniosynostosis. CDC45 encodes a component of both the pre-initiation (preIC) and CMG helicase complexes, required for initiation of DNA replication origin firing and ongoing DNA synthesis during S-phase itself, respectively, and hence is functionally distinct from previously identified MGS-associated genes. The phenotypes of affected individuals range from syndromic coronal craniosynostosis to severe growth restriction, fulfilling diagnostic criteria for Meier-Gorlin syndrome. All mutations identified were biallelic and included synonymous mutations altering splicing of physiological CDC45 transcripts, as well as amino acid substitutions expected to result in partial loss of function. Functionally, mutations reduce levels of full-length transcripts and protein in subject cells, consistent with partial loss of CDC45 function and a predicted limited rate of DNA replication and cell proliferation. Our findings therefore implicate the preIC as an additional protein complex involved in the etiology of MGS and connect the core cellular machinery of genome replication with growth, chondrogenesis, and cranial suture homeostasis. PMID:27374770

  5. Depositional environments and porosity development, Strawn Formation (middle Pennsylvanian), Wagon Wheel and HSA (Penn) fields, west Texas

    SciTech Connect

    McInturff, D.L.; Price, R.C.; Ward, R.F.

    1989-03-01

    The Wagon Wheel and HSA (Penn) fields are located on the western flank of the Central Basin platform within the Permian basin. In this area, both siliciclastic and carbonate depositional systems controlled sedimentation during Strawn time. To the east (HSA Penn field) siliciclastic fanglomerate sedimentation dominated. Several fanglomerate lobes, sourced from the Sand Hills uplift to the east, prograded westward across the platform. Interlobe swamps were common along this strand-line setting. Approximately 3 mi westward (Wagon Wheel Penn field), carbonate bank deposition dominated. Siliciclastic sands and clays commonly are intermixed within these carbonates and represent distal reaches of the siliciclastic progradational lobes. Conglomerates occur more rarely within the carbonate sequence. Carbonates from the upper Strawn (HSA 1392-P well, Wagon Wheel Penn field) demonstrate five shallowing-upward sequences. Each sequence consists of a lower subtidal phylloid algal wackestone which shallows upward into a grainstone shoal deposited above effective wave base. Transgression was rapid and marked by the subtidal phylloid algal wackestone facies overlying the grainstone shoal facies at the top of the previous sequence. Where present, chaetetids punctuate the contact between sequences. Porosity occurs as interparticle voids within the nearshore fanglomerate lobes and as leached biomolds in the grainstone shoals of the carbonate bank. Phylloid algal-rich facies are tight. Porosity is adversely affected by clastic pulses within the grainstone shoal facies and by late-stage ferroan calcite cement.

  6. 76 FR 42163 - East Penn Railroad, L.L.C.; Lease and Operation Exemption; Norfolk Southern Railway Company

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-18

    ... Surface Transportation Board East Penn Railroad, L.L.C.; Lease and Operation Exemption; Norfolk Southern... delegated the authority to determine whether to issue notices of exemption for lease transactions under 49 U... has determined that this lease and operation notice of exemption should be issued, and does so...

  7. Validation of the Penn Interactive Peer Play Scale with Preschool Children in Low-Income Families in Hong Kong

    ERIC Educational Resources Information Center

    Leung, Chi-Hung

    2014-01-01

    Play is a primary context for fostering young children's positive peer interactions. Through play, children develop the social, emotional, cognitive and language skills that contribute to the ability to establish effective relationships with peers. The Penn Interactive Peer Play Scale (PIPPS) was first developed by Fantuzzo to assess the…

  8. Repeatability and reproducibility of distraction indices in PennHIP examinations of the hip joint in dogs.

    PubMed

    Ginja, M M D; Ferreira, A J A; Silvestre, M; Gonzalo-Orden, J M; Llorens-Pena, M P

    2006-09-01

    Repeatability and reproducibility of Distraction Index (DI) measurements in the PennHIP method were evaluated in 100 dogs. The PennHIP distraction views sent to the PennHIP Analysis Center (PAC) were duplicated, digitalised, and identified with a code, and an adequate computer software was used for DI measurements. One examiner performed two DI measurement sessions, evaluating individually 200 hip joints. The scoring repeatability and reproducibility were estimated calculating the Intraclass Correlation Coefficient (ICC) between the two DI measurement sessions and between the second DI measurement session and the DI in PAC reports, respectively. The ICC for repeatability was 0.97 [95% confidence interval (CI), 0.96 to 0.98], and the ICC for reproducibility was 0.95 (95% CI, 0.93 to 0.96). The results suggest that the DI measurement method described is repeatable and can reproduce the PAC reports with confidence. Distraction indices measured in different PennHIP studies, using this DI measurement method and performed by trained researchers, can be considered interchangeable. PMID:17020141

  9. Preventing Depression among Early Adolescents in the Primary Care Setting: A Randomized Controlled Study of the Penn Resiliency Program

    ERIC Educational Resources Information Center

    Gillham, Jane E.; Hamilton, John; Freres, Derek R.; Patton, Ken; Gallop, Robert

    2006-01-01

    This study evaluated the Penn Resiliency Program's effectiveness in preventing depression when delivered by therapists in a primary care setting. Two-hundred and seventy-one 11- and 12-year-olds, with elevated depressive symptoms, were randomized to PRP or usual care. Over the 2-year follow-up, PRP improved explanatory style for positive events.…

  10. The countrate performance of the volume imaging PENN-PET scanner

    SciTech Connect

    Smith, R.J.; Karp, J.S. . Dept. of Radiology); Muehllehner, G. )

    1994-12-01

    The UGM PENN-PET Camera uses large position sensitive detectors and operates without septa. This design results in high sensitivity and 3-D imaging capability, but poses problems in high countrate situations. The maximum true countrates and random countrates have been measured, as a function of object size in the field-of-view. The countrate performance is understood in terms of the limiting process rates and event rejection in the camera. In addition, the camera is calibrated to generate absolute activity concentrations to within 5% by correcting for system deadtime with up to 3 mCi in the field of view in brain studies. This allows the performance of a variety of brain and body studies, and accurate quantitation of the data over a wide-range of imaging countrates, from [sup 18]F-FDG brain studies to [sup 15]O-water dynamic brain studies.

  11. Penn State Worry Questionnaire: structure and psychometric properties of the Chinese version*

    PubMed Central

    Zhong, Jie; Wang, Chun; Li, Jie; Liu, Jun

    2009-01-01

    The Penn State Worry Questionnaire (PSWQ) is a measure of worry phenomena and has been demonstrated valid in cross-cultural populations. The present study examined the factor structure and psychometric properties of the Chinese version of PSWQ (Ch-PSWQ) in a Chinese college sample (n=1243). Exploratory factor analysis of the Ch-PSWQ revealed a two-factor solution (engagement of worry and absence of worry). Confirmatory factor analysis and model comparison supported that the model of one factor with method effect provided the best fit to the data. The Ch-PSWQ and its factors evidenced good internal consistency and both convergent and discriminate validity. The present study supports the opinion that the second factor of PSWQ not only contains the component of evaluating pathological worry, but also might represent other traits. PMID:19283876

  12. Animal Model Development for the Penn State Pediatric Ventricular Assist Device

    PubMed Central

    Carney, Elizabeth L.; Clark, J. Brian; Myers, John L.; Peterson, Rebecca; Wilson, Ronald P.; Weiss, William J.

    2009-01-01

    In March 2004, the National Heart, Lung, and Blood Institute (NHLBI) awarded five contracts to develop devices providing circulatory support for infants and small children with congenital and acquired cardiac disease. Since 2004, the team at Penn State College of Medicine has developed a pneumatically-actuated ventricular assist device (VAD) with mechanical tilting disk valves. To date, hemodynamic performance, thrombogenesis, and hemolysis have been chronically evaluated in 16 animals, including 4 pygmy goats and 12 sheep. Major complications, mainly respiratory failure, have been encountered and resolved by a multi-disciplinary team. Multi-modal analgesia, appropriate antibiotic therapy, and attentive animal care have contributed to successful outcomes. Time after implant has ranged from 0–40 days. Most recently, a sheep implanted with Version 3 Infant VAD was electively terminated at 35 days post-implant, with no major adverse events. This report describes a successful in vivo model for evaluating a pediatric VAD. PMID:19849686

  13. Analysis of Coherent Scatter Observations collected with the new Penn State VHF Meteor Radar

    NASA Astrophysics Data System (ADS)

    Urbina, J. V.; Hackett, A. L.; Dyrud, L. P.; Fentzke, J.

    2012-12-01

    The Penn State University 50 MHz radar interferometer has been installed near Penn State campus, University Park, Pennsylvania (77.97°W, 40.70°N), to make continuous meteor observations since July 5, 2012. The antenna beam is pointed to the north in the magnetic meridian plane. In azimuth the half-power beam-width is about 3.4o, while in elevation the gain pattern peaked in the direction perpendicular to the geomagnetic field at E-region heights at about 18o elevation angle. The system uses two phased sub-arrays of four 24-element COCO strings with an east-west separation of 50 m. On transmission both sub-arrays are excited simultaneously and oriented perpendicular to the Earth's geomagnetic field lines at E- region heights. On reception each sub-array is sampled independently for interferometric detection of the scattering regions. The new radar operates at a peak power of about 30 kW and can detect all three types of meteor reflections: 1) the commonly used specular meteor trails; 2) non-specular trails, which result from plasma instability and turbulence generated field aligned irregularities (FAI); and 3) meteor head-echoes, which are a radar target moving at the speed of the meteoroid. In this paper, we present first observational trends of specular, non- specular, and head-echoes collected with the new system and discuss sampling biases of each meteor observation technique. We also present the general characteristics of continuous measurements of E-region and F-region coherent echoes using this modern radar system and compare them with coherent radar events observed at other geographic mid-latitude radar stations.

  14. FEASIBILITY ANALYSIS FOR INSTALLING A CIRCULATING FLUIDIZED BED BOILER FOR COFIRING MULTIPLE BIOFUELS AND OTHER WASTES WITH COAL AT PENN STATE UNIVERSITY

    SciTech Connect

    Bruce G. Miller; Sharon Falcone Miller; Robert Cooper; Douglas Donovan; John Gaudlip; Matthew Lapinsky; William Serencsits; Neil Raskin; Tom Steitz

    2002-10-14

    The Pennsylvania State University, under contract to the U.S. Department of Energy, National Energy Technology Laboratory is performing a feasibility analysis on installing a state-of-the-art circulating fluidized bed boiler and ceramic filter emission control device at Penn State's University Park campus for cofiring multiple biofuels and other wastes with coal, and developing a test program to evaluate cofiring multiple biofuels and coal-based feedstocks. The objective of the project is being accomplished using a team that includes personnel from Penn State's Energy Institute, Office of Physical Plant, and College of Agricultural Sciences; Foster Wheeler Energy Services, Inc.; Parsons Energy and Chemicals Group, Inc.; and Cofiring Alternatives. During this reporting period, the final technical design and cost estimate were submitted to Penn State by Foster Wheeler. In addition, Penn State initiated the internal site selection process to finalize the site for the boiler plant.

  15. A New Coherent Science Content Storyline Astronomy Course for Pre-Service Teachers at Penn State

    NASA Astrophysics Data System (ADS)

    Palma, Christopher; Plummer, Julia; Earth and Space Science Partnership

    2016-01-01

    The Earth and Space Science Partnership (ESSP) is a collaboration among Penn State scientists, science educators and seven school districts across Pennsylvania. One of the ESSP goals has been to provide pre-service teachers with new or improved science course offerings at Penn State in the Earth and Space Science domains. In particular, we aim to provide students with opportunities to learn astronomy content knowledge through teaching methods that engage them in investigations where they experience the practices used by astronomers. We have designed a new course that builds on our research into students' ideas about Solar System astronomy (Plummer et al. 2015) and the curriculum our team created for a professional development workshop for in-service teachers (Palma et al. 2013) with this same theme. The course was offered for the first time in the spring 2015 semester. We designed the course using a coherent science content storyline approach (see, e.g., Palma et al. 2014), which requires all of the student investigations to build towards a big idea in science; in this case, we chose the model for formation of our Solar System. The course led pre-service teachers through a series of investigations that model the type of instruction we hope they will adopt in their own classrooms. They were presented with a series of research questions that all tie in to the big idea of Solar System formation, and they were responsible for collecting and interpreting their own data to draw evidence-based conclusions about one aspect of this model. Students in the course were assessed on their astronomy content knowledge, but also on their ability to construct arguments using scientific reasoning to answer astronomy questions. In this poster, we will present descriptions of the investigations, the assessments used, and our preliminary results about how the course led this group of pre-service teachers to improved understanding of astronomy content and the practices astronomers use in

  16. The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier-Gorlin syndrome

    SciTech Connect

    Kuo, Alex J; Song, Jikui; Cheung, Peggie; Ishibe-Murakami, Satoko; Yamazoe, Sayumi; Chen, James K; Patel, Dinshaw J; Gozani, Or

    2012-07-11

    The recognition of distinctly modified histones by specialized 'effector' proteins constitutes a key mechanism for transducing molecular events at chromatin to biological outcomes. Effector proteins influence DNA-templated processes, including transcription, DNA recombination and DNA repair; however, no effector functions have yet been identified within the mammalian machinery that regulate DNA replication. Here we show that ORC1 - a component of ORC (origin of replication complex), which mediates pre-DNA replication licensing - contains a bromo adjacent homology (BAH) domain that specifically recognizes histone H4 dimethylated at lysine 20 (H4K20me2). Recognition of H4K20me2 is a property common to BAH domains present within diverse metazoan ORC1 proteins. Structural studies reveal that the specificity of the BAH domain for H4K20me2 is mediated by a dynamic aromatic dimethyl-lysine-binding cage and multiple intermolecular contacts involving the bound peptide. H4K20me2 is enriched at replication origins, and abrogating ORC1 recognition of H4K20me2 in cells impairs ORC1 occupancy at replication origins, ORC chromatin loading and cell-cycle progression. Mutation of the ORC1 BAH domain has been implicated in the aetiology of Meier-Gorlin syndrome (MGS), a form of primordial dwarfism, and ORC1 depletion in zebrafish results in an MGS-like phenotype. We find that wild-type human ORC1, but not ORC1-H4K20me2-binding mutants, rescues the growth retardation of orc1 morphants. Moreover, zebrafish depleted of H4K20me2 have diminished body size, mirroring the phenotype of orc1 morphants. Together, our results identify the BAH domain as a novel methyl-lysine-binding module, thereby establishing the first direct link between histone methylation and the metazoan DNA replication machinery, and defining a pivotal aetiological role for the canonical H4K20me2 mark, via ORC1, in primordial dwarfism.

  17. Review of PennDOT Publication 408 for the use of recycled co-product materials: Summary recommendations. Final report

    SciTech Connect

    Van Tassel, E.L.; Tikalsky, P.J.; Christensen, D.W.

    1999-04-30

    The purpose of this project is to decrease the institutional or perceived institutional barriers for the use of recycled and co-product materials including glass, steel slag, foundry sand, fly ash, shingle tabs, reclaimed Portland cement concrete, and scrap tires in the Pennsylvania Department of Transportation`s (PennDOT) Publications 408, Commonwealth of Pennsylvania Department of Transportation Specifications. This report reviews potential uses of each material, identifies the project that used these materials, and provides direction for future specification development.

  18. The New Meteor Radar at Penn State: Design and First Observations

    NASA Technical Reports Server (NTRS)

    Urbina, J.; Seal, R.; Dyrud, L.

    2011-01-01

    In an effort to provide new and improved meteor radar sensing capabilities, Penn State has been developing advanced instruments and technologies for future meteor radars, with primary objectives of making such instruments more capable and more cost effective in order to study the basic properties of the global meteor flux, such as average mass, velocity, and chemical composition. Using low-cost field programmable gate arrays (FPGAs), combined with open source software tools, we describe a design methodology enabling one to develop state-of-the art radar instrumentation, by developing a generalized instrumentation core that can be customized using specialized output stage hardware. Furthermore, using object-oriented programming (OOP) techniques and open-source tools, we illustrate a technique to provide a cost-effective, generalized software framework to uniquely define an instrument s functionality through a customizable interface, implemented by the designer. The new instrument is intended to provide instantaneous profiles of atmospheric parameters and climatology on a daily basis throughout the year. An overview of the instrument design concepts and some of the emerging technologies developed for this meteor radar are presented.

  19. LateNight Penn State Alcohol-Free Programming: Students Drink Less on Days They Participate

    PubMed Central

    Patrick, Megan E.; Maggs, Jennifer L.; Osgood, D. Wayne

    2011-01-01

    Despite the public health importance of alcohol-free social programs for college students, the majority of existing campus strategies have not been empirically evaluated. This study utilized repeated daily reports to examine the association between attendance at campus-led alcohol-free programming and alcohol use on specific days while controlling for individuals' typical rates of use. The current study assessed students' participation in the Late-Night Penn State (LNPS) alcohol-free programming and amount of alcohol use at a daily level, in order to determine whether students consumed less alcohol on days they attended LNPS compared to weekend days they did not attend. First-year college students reported their daily social activity involvement and alcohol use via 14 consecutive daily web-based surveys. Multilevel regression analyses modeled variation in alcohol use on weekend days (N=3,350) nested within people (N=689 people, 51% women). Analyses focused on within-individual differences between nights attending and not attending LNPS, thereby controlling for stable individual differences, measured and unmeasured. Results indicated that students drank less on days they attended LNPS and on days they stayed in (rather than going to bars/parties, other campus events, or entertainment), both especially among women. These results suggest that alcohol-free social programs may be an effective strategy for decreasing alcohol use on days when students attend alcohol-free events rather than going to other events or gatherings. PMID:20020210

  20. Final report to DOE: Matching Grant Program for the Penn State University Nuclear Engineering Program

    SciTech Connect

    Jack S. Brenizer, Jr.

    2003-01-17

    The DOE/Industry Matching Grant Program is designed to encourage collaborative support for nuclear engineering education as well as research between the nation's nuclear industry and the U.S. Department of Energy (DOE). Despite a serious decline in student enrollments in the 1980s and 1990s, the discipline of nuclear engineering remained important to the advancement of the mission goals of DOE. The program is designed to ensure that academic programs in nuclear engineering are maintained and enhanced in universities throughout the U.S. At Penn State, the Matching Grant Program played a critical role in the survival of the Nuclear Engineering degree programs. Funds were used in a variety of ways to support both undergraduate and graduate students directly. Some of these included providing seed funding for new graduate research initiatives, funding the development of new course materials, supporting new teaching facilities, maintenance and purchase of teaching laboratory equipment, and providing undergraduate scholarships, graduate fellowships, and wage payroll positions for students.

  1. A thrombus susceptibility comparison of two pulsatile Penn State 50 cc left ventricular assist device designs.

    PubMed

    Navitsky, Michael A; Deutsch, Steven; Manning, Keefe B

    2013-01-01

    Left ventricular assist devices (LVADs) have proven successful as bridge to transplant devices for patients awaiting donor organs. While survival rates continue to increase, destination therapy remains hindered by thrombus formation within the device. Research has shown that thrombosis is correlated to the fluid dynamics within the device and may be a result of sustained shear rates below 500 s(-1) on the polyurethane blood sac used in the Penn State pulsatile LVAD. Particle image velocimetry is used to compare flow within two 50 cc LVAD designs to assess fluid patterns and quantify wall shear rates in regions known from in vivo studies to be susceptible to thrombus formation. The two designs differ in their front face geometry. The V-1 model has an outward-facing "dome" whereas the face of the V-2 model is flat. A thrombus susceptibility metric, which uses measured wall shear rates and exposure times, was applied to objectively compare pump designs over the entire cardiac cycle. For each design, there are regions where wall shear rates remained below 500 s(-1) for the entire cardiac cycle resulting in high thrombus susceptibility potential. Results of this study indicate that the V-2 device had an overall lower propensity for thrombus formation in the current region of interest. PMID:22825798

  2. Sensing for directed energy deposition and powder bed fusion additive manufacturing at Penn State University

    NASA Astrophysics Data System (ADS)

    Nassar, Abdalla R.; Reutzel, Edward W.; Brown, Stephen W.; Morgan, John P.; Morgan, Jacob P.; Natale, Donald J.; Tutwiler, Rick L.; Feck, David P.; Banks, Jeffery C.

    2016-04-01

    Additive manufacturing of metal components through directed energy deposition or powder bed fusion is a complex undertaking, often involving hundreds or thousands of individual laser deposits. During processing, conditions may fluctuate, e.g. material feed rate, beam power, surrounding gas composition, local and global temperature, build geometry, etc., leading to unintended variations in final part geometry, microstructure and properties. To assess or control as-deposited quality, researchers have used a variety of methods, including those based on sensing of melt pool and plume emission characteristics, characteristics of powder application, and layer-wise imaging. Here, a summary of ongoing process monitoring activities at Penn State is provided, along with a discussion of recent advancements in the area of layer-wise image acquisition and analysis during powder bed fusion processing. Specifically, methods that enable direct comparisons of CAD model, build images, and 3D micro-tomographic scan data will be covered, along with thoughts on how such analyses can be related to overall process quality.

  3. Fruit consumption, fitness, and cardiovascular health in female adolescents: the Penn State Young Women's Health Study.

    PubMed

    Lloyd, T; Chinchilli, V M; Rollings, N; Kieselhorst, K; Tregea, D F; Henderson, N A; Sinoway, L I

    1998-04-01

    The objective of this study was to compare the relations among nutrient intake, fitness, serum antioxidants, and cardiolipoprotein profiles in female adolescents. The study design was a cross-sectional analysis of the Penn State Young Women's Health Study. The present study was performed with the entire cohort (n = 86) when they were 17.1+/-0.5 y (x+/-SD) of age. Primary measurements included cardiolipoprotein indexes, serum antioxidants, nutrient intakes, aerobic fitness, and percentage body fat. The cohort was stratified by estimated maximal oxygen uptake (VO2max) measurements and by percentage body fat. The fifth quintile by estimated VO2max had significantly lower percentage body fat, higher athletic scores, higher fruit intake, lower total serum cholesterol, and lower ratios of total serum cholesterol to HDL cholesterol than members of the first quintile. When the members of the first and fifth quintiles by percentage body fat were compared, the first quintile had significantly lower weight, lower body mass index, higher estimated VO2max, higher athletic scores, lower ratios of total serum cholesterol to HDL cholesterol, and higher fruit, carbohydrate, and fiber intakes. Correlation analyses performed with the data for the entire cohort showed fruit consumption to be positively correlated with estimated VO2max, and predicted VO2max to be positively correlated with circulating beta-carotene and alpha-tocopherol. This study provided evidence that the positive associations of exercise and fruit consumption with cardiovascular health apply to female adolescents as well as to adults. PMID:9537609

  4. Chronic In Vivo Testing of the Penn State Infant Ventricular Assist Device

    PubMed Central

    Weiss, William J.; Carney, Elizabeth L.; Clark, J. Brian; Peterson, Rebecca; Cooper, Timothy K.; Nifong, Thomas P.; Siedlecki, Christopher A; Hicks, Dennis; Doxtater, Bradley; Lukic, Branka; Yeager, Eric; Reibson, John; Cysyk, Joshua; Rosenberg, Gerson; Pierce, William S.

    2011-01-01

    The Penn State Infant Ventricular Assist Device is a 12-14 ml stroke volume pneumatically actuated pump, with custom Björk-Shiley monostrut valves, developed under the National Heart, Lung, and Blood Institute (NHLBI) Pediatric Circulatory Support program. In this report we describe the 7 most recent chronic animal studies of the Infant VAD in the juvenile ovine model, with a mean body weight of 23.5 +/- 4.1 kg. The goal of 4-6 weeks survival was achieved in 5 of 7 studies, with support duration ranging from 5 to 41 days; mean 26.1 days. Anticoagulation was accomplished using unfractionated heparin, and study animals were divided into 2 protocol groups: the first based on a target activated partial thromboplastin time of 1.5 to 2 times normal, and a second group using a target thromboelastography R-time of 2 times normal. The second group required significantly less heparin, which was verified by barely detectable heparin activity (anti-Xa). In both groups, there was no evidence of thromboembolism except in one animal with a chronic infection and fever. Device thrombi were minimal, and were further reduced by introduction of the custom valve. These results are consistent with results of adult VAD testing in animals, and are encouraging given the extremely low levels of anticoagulation in the second group. PMID:22157073

  5. Resiliency Training in Indian Children: A Pilot Investigation of the Penn Resiliency Program

    PubMed Central

    Sankaranarayanan, Aruna; Cycil, Chandrika

    2014-01-01

    This paper examines the effectiveness of the Penn Resiliency Program (PRP) in an urban Indian setting. The PRP is a program to prevent depression in early adolescence and has proved successful in changing children’s attributional style of life events. While the program has been successful in preventing symptoms of depression in Western populations, the current study explored whether this program could be effective with an Indian sample. The aim of the current study was twofold; first, to study the attributional style of early adolescents in India and identify negative effects (if any) and second, to gain insights in using the PRP as a tool to change explanatory styles in Indian children. A total of 58 children participated in the study (Intervention group n = 29 and Control group n = 29). An Analysis of Covariance comparing post-test scores on Children’s Attributional Style Questionnaire (CASQ) while controlling for baseline scores indicated that children in the intervention group exhibited a significant reduction in pessimistic explanatory style and an increase in optimistic orientation compared to children in the control group. This indicates that the program was effective in changing negative attribution styles among upper-class Indian school children. Future work may look into the longer impact of the program as well as further considerations into adapting the program for a middle class population. PMID:24739766

  6. Preventing adolescents’ externalizing and internalizing symptoms: Effects of the Penn Resiliency Program

    PubMed Central

    Cutuli, J. J.; Gillham, Jane E.; Chaplin, Tara M.; Reivich, Karen J.; Seligman, Martin E. P.; Gallop, Robert J.; Abenavoli, Rachel M.; Freres, Derek R.

    2014-01-01

    This study reports secondary outcome analyses from a past study of the Penn Resiliency Program (PRP), a cognitive-behavioral depression prevention program for middle-school aged children. Middle school students (N = 697) were randomly assigned to PRP, PEP (an alternate intervention), or control conditions. Gillham et al., (2007) reported analyses examining PRP’s effects on average and clinical levels of depression symptoms. We examine PRP’s effects on parent-, teacher-, and self-reports of adolescents’ externalizing and broader internalizing (depression/anxiety, somatic complaints, and social withdrawal) symptoms over three years of follow-up. Relative to no intervention control, PRP reduced parent-reports of adolescents’ internalizing symptoms beginning at the first assessment after the intervention and persisting for most of the follow-up assessments. PRP also reduced parent-reported conduct problems relative to no-intervention. There was no evidence that the PRP program produced an effect on teacher- or self-report of adolescents’ symptoms. Overall, PRP did not reduce symptoms relative to the alternate intervention, although there is a suggestion of a delayed effect for conduct problems. These findings are discussed with attention to developmental trajectories and the importance of interventions that address common risk factors for diverse forms of negative outcomes. PMID:24634897

  7. A Thrombus Susceptibility Comparison of Two Pulsatile Penn State 50cc Left Ventricular Assist Device Designs

    PubMed Central

    Navitsky, Michael A.; Deutsch, Steven; Manning, Keefe B.

    2012-01-01

    Left ventricular assist devices (LVADs) have proven successful as bridge to transplant devices for patients awaiting donor organs. While survival rates continue to increase, destination therapy remains hindered by thrombus formation within the device. Research has shown that thrombosis is correlated to the fluid dynamics within the device and may be a result of sustained shear rates below 500 s−1 on the polyurethane blood sac used in the Penn State pulsatile LVAD. Particle image velocimetry is used to compare flow within two 50 cc LVAD designs to assess fluid patterns and quantify wall shear rates in regions known from in vivo studies to be susceptible to thrombus formation. The two designs differ in their front face geometry. The V-1 model has an outward facing “dome” whereas the face of the V-2 model is flat. A thrombus susceptibility metric, which uses measured wall shear rates and exposure times, was applied to objectively compare pump designs over the entire cardiac cycle. For each design, there are regions where wall shear rates remained below 500 s−1 for the entire cardiac cycle resulting in high thrombus susceptibility potential. Results of this study indicate that the V-2 device had an overall lower propensity for thrombus formation in the current region of interest. PMID:22825798

  8. Preliminary Normative Data on the Penn State University Symbol Cancellation Task With Nonconcussed Adolescents.

    PubMed

    Conder, Robert L; Conder, Alanna A; Register-Mihalik, Johna; Conder, Lauren H; Newton, Shannon

    2015-01-01

    Visual concentration impairment after neurologic injury is frequent, making its identification a critical component of neurocognitive concussion assessment. Visual target cancellation tests such as the Penn State University Symbol Cancellation Task (PSUSCT) have been widely used in assessing professional and collegiate athletes. To date, there are no normative studies using the PSUSCT with an adolescent population. Given that 38 million children and adolescents participate in sports and an estimated 5% to 10% are concussed annually, adolescent normative data are critically needed to evaluate concussions in this vulnerable population. The purpose of this study was to provide adolescent normative data on the PSUSCT. Participants included 40 healthy, nonconcussed high school students aged 14 to 19 years old (20 men, 20 women). Participants were administered Forms A and C of the PSUSCT within a 4-day period. Data analysis examined hits, omission errors, and commission errors, with descriptive statistics calculated for the total sample and for subgroups by gender and age. Study 1 provided normative adolescent data on Form A. Study 2 examined practice effects and established reliable change indexes (RCIs) by comparing results on Forms A and C. Neither Study 1 nor Study 2 demonstrated significant group differences for gender or age. In conclusion, this study presents adolescent normative data, apparent practice effects, and RCIs on the PSUSCT. These norms provide data needed to appropriately include the PSUSCT in baseline and postinjury concussion evaluation batteries with adolescent student-athletes. Findings should be replicated with a larger, more heterogeneous sample. PMID:25072106

  9. Resiliency training in Indian children: a pilot investigation of the Penn Resiliency Program.

    PubMed

    Sankaranarayanan, Aruna; Cycil, Chandrika

    2014-04-01

    This paper examines the effectiveness of the Penn Resiliency Program (PRP) in an urban Indian setting. The PRP is a program to prevent depression in early adolescence and has proved successful in changing children's attributional style of life events. While the program has been successful in preventing symptoms of depression in Western populations, the current study explored whether this program could be effective with an Indian sample. The aim of the current study was twofold; first, to study the attributional style of early adolescents in India and identify negative effects (if any) and second, to gain insights in using the PRP as a tool to change explanatory styles in Indian children. A total of 58 children participated in the study (Intervention group n = 29 and Control group n = 29). An Analysis of Covariance comparing post-test scores on Children's Attributional Style Questionnaire (CASQ) while controlling for baseline scores indicated that children in the intervention group exhibited a significant reduction in pessimistic explanatory style and an increase in optimistic orientation compared to children in the control group. This indicates that the program was effective in changing negative attribution styles among upper-class Indian school children. Future work may look into the longer impact of the program as well as further considerations into adapting the program for a middle class population. PMID:24739766

  10. In vitro evaluation of the DP-4M PennCentury insufflator.

    PubMed

    Hoppentocht, M; Hoste, C; Hagedoorn, P; Frijlink, H W; de Boer, A H

    2014-09-01

    Dry powder formulations for inhalation have to be screened in animal studies for therapeutic efficacy and safety aspects and both are significantly affected by the dose and the particle size distribution (PSD) of the aerosol that is given. One of the most frequently used apparatus for pulmonary delivery of dry powder formulations in mice studies is the PennCentury DP-4M Dry Powder Insufflator. To make researchers of future preclinical animal studies with the DP-4M insufflator aware of the pitfalls regarding the conclusions to be drawn from their data, we investigated the dispersion behaviour by the DP-4M insufflator using two to three different powder preparation techniques for four different compounds. The primary PSDs of the different formulations were determined in duplicate by laser diffraction analysis. To measure the PSDs of the aerosols obtained with the DP-4M insufflator, the same diffractometer was used in combination with an in-house constructed adapter for the insufflator. The dispersion efficiency and delivered dose were highly affected by the amount of air available for dispersion; the 200 μL of air recommended for the type of insufflator used was insufficient for adequate dispersion. In contrast, the weighed dose did not have a profound effect on the dispersion behaviour and the delivered dose of the DP-4M insufflator. Also the physico-chemical powder properties and the applied particle preparation technique influenced the amount and PSD of the delivered aerosol only to a limited extend, with a few exceptions. We advise researchers to investigate the dispersion efficiency and delivered dose from the DP-4M insufflator with the formulation under investigation prior to in vivo studies and it may be necessary to optimise the formulation for administration to mice. PMID:24993307

  11. Massively parallel implementation of the Penn State/NCAR Mesoscale Model

    SciTech Connect

    Foster, I.; Michalakes, J.

    1992-01-01

    Parallel computing promises significant improvements in both the raw speed and cost performance of mesoscale atmospheric models. On distributed-memory massively parallel computers available today, the performance of a mesoscale model will exceed that of conventional supercomputers; on the teraflops machines expected within the next five years, performance will increase by several orders of magnitude. As a result, scientists will be able to consider larger problems, more complex model processes, and finer resolutions. In this paper. we report on a project at Argonne National Laboratory that will allow scientists to take advantage of parallel computing technology. This Massively Parallel Mesoscale Model (MPMM) will be functionally equivalent to the Penn State/NCAR Mesoscale Model (MM). In a prototype study, we produced a parallel version of MM4 using a static (compile-time) coarse-grained patch'' decomposition. This code achieves one-third the performance of a one-processor CRAY Y-MP on twelve Intel 1860 microprocessors. The current version of MPMM is based on all MM5 and uses a more fine-grained approach, decomposing the grid as finely as the mesh itself allows so that each horizontal grid cell is a parallel process. This will allow the code to utilize many hundreds of processors. A high-level language for expressing parallel programs is used to implement communication strearns between the processes in a way that permits dynamic remapping to the physical processors of a particular parallel computer. This facilitates load balancing, grid nesting, and coupling with graphical systems and other models.

  12. Massively parallel implementation of the Penn State/NCAR Mesoscale Model

    SciTech Connect

    Foster, I.; Michalakes, J.

    1992-12-01

    Parallel computing promises significant improvements in both the raw speed and cost performance of mesoscale atmospheric models. On distributed-memory massively parallel computers available today, the performance of a mesoscale model will exceed that of conventional supercomputers; on the teraflops machines expected within the next five years, performance will increase by several orders of magnitude. As a result, scientists will be able to consider larger problems, more complex model processes, and finer resolutions. In this paper. we report on a project at Argonne National Laboratory that will allow scientists to take advantage of parallel computing technology. This Massively Parallel Mesoscale Model (MPMM) will be functionally equivalent to the Penn State/NCAR Mesoscale Model (MM). In a prototype study, we produced a parallel version of MM4 using a static (compile-time) coarse-grained ``patch`` decomposition. This code achieves one-third the performance of a one-processor CRAY Y-MP on twelve Intel 1860 microprocessors. The current version of MPMM is based on all MM5 and uses a more fine-grained approach, decomposing the grid as finely as the mesh itself allows so that each horizontal grid cell is a parallel process. This will allow the code to utilize many hundreds of processors. A high-level language for expressing parallel programs is used to implement communication strearns between the processes in a way that permits dynamic remapping to the physical processors of a particular parallel computer. This facilitates load balancing, grid nesting, and coupling with graphical systems and other models.

  13. Brown dwarf candidates from the PennState-Toruń Planet Search with the Hobby-Eberly Telescope .

    NASA Astrophysics Data System (ADS)

    Niedzielski, A.; Wolszczan, A.; Adamów, M.; Nowak, G.; Deka, B.; Górecka, M.; Kowalik, K.

    We present preliminary results of a brown dwarf (BD) detection in a ˜1000 star sample monitored with the ongoing PennState-Toruń Centre for Astronomy Planet Search. Contrary to most other projects, our sample contains a substantial fraction of evolved stars ranging from sub-giants up to bright giants, allowing us to study companions to stars more massive than ˜1.5 M⊙. For Main Sequence stars, this limit is set by effective temperature and rotation velocity. Our relatively long list of about a dozen candidates suggests that the BD frequency may rise with stellar mass as it does in the case of planets \\citep{lm2007}.

  14. Sea-Level Static Testing of the Penn State Two-Dimensional Rocket-Based Combined Cycle (RBCC) Testbed

    NASA Technical Reports Server (NTRS)

    Cramer, J. M.; Marshall, W. M.; Pal, S.; Santoro, R. J.

    2003-01-01

    Twin thruster tests have been conducted with the Penn State RBCC test article operating at sea- level static conditions. Significant differences were observed in the performance characteristics for two different thruster centerline spacings. Changing the thruster spacing from 2.50 to 1.75 in. reduced the entrained air velocity (-17%) and the thrust (-7%) for tests at a thruster chamber pressure of 200 psia and MR = 8. In addition, significant differences were seen in the static pressure profiles, the Raman spectroscopy profiles, and the acoustic power spectrum for these two configurations.

  15. Evaluation of hydrologic data collected at the North Penn Area 12 Superfund Site, Montgomery County, Pennsylvania

    USGS Publications Warehouse

    Senior, Lisa A.; Grazul, Kevin E.; Wood, Charles R.

    1998-01-01

    The North Penn Area 12 Superfund Site is underlain by the Lockatong Formation, which consists of interbedded gray to black siltstone and shale. The beds of the Lockatong Formation strike northeast and dip about 10d to 20d to the northwest in the vicinity of the site. Ground water moves through fractures that are nearly vertical and horizontal in the shale and siltstone. Permeability and storage are very low. Borehole-geophysical logs were obtained from eight wells to determine the location of fractures, water-producing and water-receiving intervals, and intervals of borehole flow. The logs also were used to quantify fluid movement in the borehole, to characterize the lithology, and to obtain data on well construction. The logs indicate fractures at depths less than 100 feet are more frequent and generally are more productive than fractures at depths greater than 100 feet. The fluid resistivity of water in shallow intervals usually was greater than that in deeper intervals. The rate and direction of fluid movement under nonpumping conditions differs in the boreholes logged. In the northwest part of the site, no vertical flow was detected in three wells and very small amounts of flow were measured in two wells. In the southwest part of the site, downward flow was measured in two wells. Aquifer-isolation tests in three wells provided information on hydraulic heads and specific capacities in discrete vertical intervals and allowed collection of water samples form discrete water-bearing intervals. Natural annual fluctuations of water levels in 11 wells ranged form 11.4 to 28.3 feet. Seven of the 11 wells gave very similar water-level hydrographs. The four southernmost wells on the site show rises in water levels after precipitation much sooner than the other seven wells. Two other wells show daily fluctuations caused by pumping. A potentiometric-surface map of the site and vicinity was prepared from water-level measurements made in late July 1995. The map can be used to

  16. Analysis of geophysical logs, at North Penn Area 6 Superfund Site, Lansdale, Montgomery County, Pennsylvania

    USGS Publications Warehouse

    Conger, Randall W.

    1999-01-01

    The U.S. Geological Survey (USGS), as part of technical assistance to the U.S. Environmental Protection Agency (USEPA), collected borehole geophysical log data in 34 industrial, commercial, and public supply wells and 28 monitor wells at the North Penn Area 6 Superfund Site, in Lansdale, Pa., from August 22, 1995, through August 29, 1997. The wells range in depth from 50 to 1,027 feet below land surface and are drilled in Triassic-age shales and siltstones of the Brunswick Group and Lockatong Formation. The geophysical log data were collected to help describe the hydrogeologic framework in the area and to provide guidance in the reconstruction of the 28 monitor wells drilled during summer 1997. At the time of logging, all wells had open-hole construction. The geophysical logs, caliper, fluid-resistivity, and fluid-temperature, and borehole video logs were used to determine the vertical distribution of water-bearing fractures. Heatpulse-flowmeter measurements were used to determine vertical borehole flow under pumping and nonpumping conditions. The most productive fractures generally could be determined from heatpulse-flowmeter measurements under pumping conditions. Vertical borehole flow was measured under nonpumping conditions in most wells that had more than one water-bearing fracture. Upward flow was measured in 35 wells and probably is a result of natural head differences between fractures in the local ground-water-flow system. Downward flow was measured in 11 wells and commonly indicated differences in hydraulic heads of the fractures caused by nearby pumping. Both upward and downward flow was measured in three wells. No flow was detected in eight wells. Natural-gamma-ray logs were used to estimate the attitude of bedding. Thin shale marker beds, shown as spikes of elevated radioactivity in the natural-gamma logs of some wells throughout the area, enable the determination of bedding-plane orientation from three-point correlations. Generally, the marker beds in

  17. Penn State geoPebble system: Design,Implementation, and Initial Results

    NASA Astrophysics Data System (ADS)

    Urbina, J. V.; Anandakrishnan, S.; Bilen, S. G.; Fleishman, A.; Burkett, P.

    2014-12-01

    The Penn State geoPebble system is a new network of wirelessly interconnected seismic and GPS sensor nodes with flexible architecture. This network will be used for studies of ice sheets in Antarctica and Greenland, as well as to investigate mountain glaciers. The network will consist of ˜150 geoPebbles that can be deployed in a user-defined spatial geometry. We present our design methodology, which has enabled us to develop these state-of- the art sensors using commercial-off-the-shelf hardware combined with custom-designed hardware and software. Each geoPebble is a self- contained, wirelessly connected sensor for collecting seismic measurements and position information. Key elements of each node encompasses a three-component seismic recorder, which includes an amplifier, filter, and 24- bit analog-to-digital converter that can sample up to 10 kHz. Each unit also includes a microphone channel to record the ground-coupled airwave. The timing for each node is available from GPS measurements and a local precision oscillator that is conditioned by the GPS timing pulses. In addition, we record the carrier-phase measurement of the L1 GPS signal in order to determine location at sub-decimeter accuracy (relative to other geoPebbles within a few kilometers radius). Each geoPebble includes 16 GB of solid-state storage, wireless communications capability to a central supervisory unit, and auxiliary measurements capability (including tilt from accelerometers, absolute orientation from magnetometers and temperature). A novel aspect of the geoPebble is a wireless charging system for the internal battery (using inductive coupling techniques). The geoPebbles include all the sensors (geophones, GPS, microphone), communications (WiFi), and power (battery and charging) internally, so the geoPebble system can operate without any cabling connections (though we do provide an external connector so that different geophones can be used). We report initial field-deployment results and

  18. Reliability and Validity of the Korean Version of the Penn State Worry Questionnaire in Primary School Children

    PubMed Central

    Kang, Sung-Goo; Shin, Jin-Hee

    2010-01-01

    Worry is a generalized psychological phenomenon seen among most people. When worry is excessive and nearly uncontrollable, people usually suffer psychological pain. The Penn State Worry Questionnaire for Children (PSWQ-C) was developed to measure worry objectively. It comprises 14 items for measuring excessive, generalized, and uncontrollable worry in children. This study, conducted with a large group of elementary children (3rd through 6th graders, ages 8-12 yr; N=973), investigated the reliability and validity of the Korean version of the Penn State Worry Questionnaire for Children (PSWQ-CK). The PSWQ-CK showed high reliability by test-retest and also excellent internal consistency results. To examine the validity of the PSWQ-CK, we calculated its correlation with the Revised Children's Manifest Anxiety Scale (RCMAS). The PSWQ-CK had a higher correlation with the worry/oversensitivity factor than with other subscales of the RCMAS, and it showed no correlation with the lie factor. When 3 reversed PSWQ-CK items were eliminated, the instrument showed higher internal consistency. However, this did not improve its correlation with other anxiety-measuring tools. In conclusion, the PSWQ-CK's reliability and validity were satisfactory, and it is a useful tool for objectively measuring the worry of Korean children of this age group. PMID:20676335

  19. Steady state hemodynamic and energetic characterization of the Penn State/3M Health Care Total Artificial Heart.

    PubMed

    Weiss, W J; Rosenberg, G; Snyder, A J; Pierce, W S; Pae, W E; Kuroda, H; Rawhouser, M A; Felder, G; Reibson, J D; Cleary, T J; Ford, S K; Marlotte, J A; Nazarian, R A; Hicks, D L

    1999-01-01

    Total Artificial Heart (TAH) development at Penn State University and 3M Health Care has progressed from design improvements and manufacturing documentation to in vitro and in vivo testing to characterize the system's hemodynamic response and energetic performance. The TAH system is completely implantable and intended for use as an alternative to transplantation. It includes a dual pusher plate pump and rollerscrew actuator, welded electronics and battery assembly, transcutaneous energy transmission system, telemetry, and a compliance chamber. In vitro testing was conducted on a Penn State mock circulatory loop with glycerol/water solution at body temperature. Tests were performed to characterize the preload and afterload response, left atrial pressure control, and power consumption. A sensitive preload response was demonstrated with left atrial pressure safely maintained at less than 15 mm Hg for flow rates up to 7.5 L/min. Variations in aortic pressure and pulmonary vascular resistance were found to have minimal effects on the preload sensitivity and left atrial pressure control. In vivo testing of the completely implanted system in its final configuration was carried out in two acute studies using implanted temperature sensors mounted on the electronics, motor, and energy transmission coil in contact with adjacent tissue. The mean temperature at the device-tissue interface was less than 4 degrees C above core temperature. PMID:10360721

  20. Flow behavior within the 12-cc Penn State pulsatile pediatric ventricular assist device: an experimental study of the initial design.

    PubMed

    Manning, Keefe B; Wivholm, Brandon D; Yang, Ning; Fontaine, Arnold A; Deutsch, Steven

    2008-06-01

    Planar particle image velocimetry was used to explore the flow behavior of the newly designed 12-cc Penn State pneumatic pediatric assist pump. Wall shear maps complemented the velocity data. Bjork-Shiley Monostrut 17-mm mechanical heart valves were used in the inlet and outlet ports. In comparison with larger Penn State pumps, the 12-cc device is not only smaller but has reduced valve effective orifice areas and more highly angled valve ports. In contrast to results from the larger pumps, the flow field was highly three dimensional during early diastole with poorer penetration by the valve inlet jet. This led to a later start to a "wall washing" rotational pattern. A significant separation region, never before observed, was created upstream of the outlet valve leaflet during late diastole--effectively reducing the area and increasing the pressure drop through the valve. Wall shear maps suggest that regions of low shear might persist throughout the cycle at the bottom of the pump on the outlet side. An attempt to improve the flow field characteristics by exploring different valves, valve orientations and inlet valve angles, systolic/diastolic flow timing, and perhaps a larger outlet valve was planned. PMID:18422800

  1. The Penn State - Toruń Centre for Astronomy Planet Search stars

    NASA Astrophysics Data System (ADS)

    Niedzielski, A.; Deka-Szymankiewicz, B.; Adamczyk, M.; Adamów, M.; Nowak, G.; Wolszczan, A.

    2016-01-01

    Aims: We present the complete spectroscopic analysis of 455 stars observed within the Penn State - Toruń Centre for Astronomy Planet Search (PTPS) with the High Resolution Spectrograph of the 9.2 m Hobby-Eberly Telescope. We also present the total sample of 744 evolved stars of the PTPS and discuss masses of stellar hosts in our and other surveys devoted to evolved planetary systems. Methods: Stellar atmospheric parameters were determined through a strictly spectroscopic LTE analysis of equivalent widths of Fe I and Fe II lines. Rotational velocities were obtained from fitting synthetic spectra. Radial velocities were obtained from fitting a Gaussian function to the cross-correlation function. We determined stellar masses, ages, and luminosities with a Bayesian analysis of theoretical isochrones. The radii were calculated either from derived masses and log g or from Teff and luminosities. Results: We present basic atmospheric parameters (Teff, log g, vt and [Fe/H]), rotation velocities, and absolute radial velocities as well as luminosities, masses, ages and radii for 402 stars (including 11 single-line spectroscopic binaries) that are mostly subgiants and giants. For 272 of them we present parameters for the first time. For another 53 stars we present estimates of Teff and log g based on photometric calibrations. More than half of the objects were found to be subgiants, but there is also a large group of giants, and a few stars appear to be dwarfs. The results show that the sample is composed of stars with masses ranging from 0.52 to 3.21 M⊙, 17 of which have masses ≥2.0 M⊙. The stellar radii range from 0.66 to 36.04 R⊙, with the vast majority having radii between 2.0 and 4.0 R⊙. They are generally less metal abundant than the Sun with a median [ Fe/H ] = -0.07. For 62 stars that we have in common with other planet searches, the stellar atmospheric parameters we found agree very well. We also present basic properties of the complete list of 744 stars

  2. FEASIBILITY ANALYSIS FOR INSTALLING A CIRCULATING FLUIDIZED BED BOILER FOR COFIRING MULTIPLE BIOFUELS AND OTHER WASTES WITH COAL AT PENN STATE UNIVERSITY

    SciTech Connect

    Bruce G. Miller; Sharon Falcone Miller; Robert Cooper; Douglas Donovan; John Gaudlip; Matthew Lapinsky; William Serencsits; Neil Raskin; Tom Steitz

    2002-07-12

    The Pennsylvania State University, under contract to the U.S. Department of Energy (DOE), National Energy Technology Laboratory (NETL) is performing a feasibility analysis on installing a state-of-the-art circulating fluidized bed (CFB) boiler and ceramic filter emission control device at Penn State's University Park campus for cofiring multiple biofuels and other wastes with coal, and developing a test program to evaluate cofiring multiple biofuels and coal-based feedstocks. Penn State currently operates an aging stoker-fired steam plant at its University Park campus and has spent considerable resources over the last ten to fifteen years investigating boiler replacements and performing life extension studies. This effort, in combination with a variety of agricultural and other wastes generated at the agricultural-based university and the surrounding rural community, has led Penn State to assemble a team of fluidized bed and cofiring experts to assess the feasibility of installing a CFB boiler for cofiring biomass and other wastes along with coal-based fuels. The objective of the project is being accomplished using a team that includes personnel from Penn State's Energy Institute, Office of Physical Plant, and College of Agricultural Sciences; Foster Wheeler Energy Services, Inc.; Parsons Energy and Chemicals Group, Inc.; and Cofiring Alternatives.

  3. IMPLEMENTATION AND EXPERIMENTATION ON AN ADVANCED LAND-SURFACE/PBL MODEL IN THE PENN STATE/NCAR MESOSCALE MODEL (MM4)

    EPA Science Inventory

    A more advanced surface/PBL model is implemented in the Penn State/NCAR Mesoscale Model Version 4 (MM4) which is utilized to provide meteorological data to the Regional Acid Deposition Model (RADM). he diurnal evolution of the Planetary Boundary Layer (PBL) and its dynamic charac...

  4. FEASIBILITY ANALYSIS FOR INSTALLING A CIRCULATING FLUIDIZED BED BOILER FOR COFIRING MULTIPLE BIOFUELS AND OTHER WASTES WITH COAL AT PENN STATE UNIVERSITY

    SciTech Connect

    Bruce G. Miller; Sharon Falcone Miller; Robert Cooper; Douglas Donovan; John Gaudlip; Matthew Lapinsky; William Serencsits; Neil Raskin; Dale Lamke; Joseph J. Battista

    2001-03-31

    The Pennsylvania State University, under contract to the U.S. Department of Energy (DOE), National Energy Technology Laboratory (NETL) is performing a feasibility analysis on installing a state-of-the-art circulating fluidized bed (CFB) boiler and ceramic filter emission control device at Penn State's University Park campus for cofiring multiple biofuels and other wastes with coal, and developing a test program to evaluate cofiring multiple biofuels and coal-based feedstocks. Penn State currently operates an aging stoker-fired steam plant at its University Park campus and has spent considerable resources over the last ten to fifteen years investigating boiler replacements and performing life extension studies. This effort, in combination with a variety of agricultural and other wastes generated at the agricultural-based university and the surrounding rural community, has led Penn State to assemble a team of fluidized bed and cofiring experts to assess the feasibility of installing a CFB boiler for cofiring biomass and other wastes along with coal-based fuels. The objective of the project is being accomplished using a team that includes personnel from Penn State's Energy Institute and the Office of Physical Plant, Foster Wheeler Energy Services, Inc., and Cofiring Alternatives.

  5. Preventing depression among early adolescents in the primary care setting: a randomized controlled study of the Penn Resiliency Program.

    PubMed

    Gillham, Jane E; Hamilton, John; Freres, Derek R; Patton, Ken; Gallop, Robert

    2006-04-01

    This study evaluated the Penn Resiliency Program's effectiveness in preventing depression when delivered by therapists in a primary care setting. Two-hundred and seventy-one 11- and 12-year-olds, with elevated depressive symptoms, were randomized to PRP or usual care. Over the 2-year follow-up, PRP improved explanatory style for positive events. PRP's effects on depressive symptoms and explanatory style for negative events were moderated by sex, with girls benefiting more than boys. Stronger effects were seen in high-fidelity groups than low-fidelity groups. PRP did not significantly prevent depressive disorders but significantly prevented depression, anxiety, and adjustment disorders (when combined) among high-symptom participants. Findings are discussed in relation to previous PRP studies and research on the dissemination of psychological interventions. PMID:16741684

  6. The Influence of Device Position on the Flow within the Penn State 12 cc Pediatric Ventricular Assist Device

    PubMed Central

    Schönberger, Markus; Deutsch, Steven; Manning, Keefe B.

    2012-01-01

    Ventricular assist devices are a commonly used heart failure therapy for adult patients as bridge-to-transplant or bridge-to-recovery tool. The application of adult ventricular assist devices in pediatric patients has led to increased thrombotic events. Therefore, we have been developing a pediatric ventricular assist device, the Penn State 12 cc PVAD. It is designed for patients with a body weight of 5 to 15 kg and has a stroke volume of 12 cc. Clot formation is the major concern. It is correlated to the coagulability of blood, the blood contacting materials and the fluid dynamics within the system. The intent is for the PVAD to be a long term therapy. Therefore, the system may be oriented in different positions according to the patient’s behavior. This study evaluates for the first time the impact of position on the flow patterns within the Penn State 12 cc PVAD, which may help to improve the PVAD design concerning chamber and ports geometries. The fluid dynamics are visualized by particle image velocimetry. The evaluation is based on inlet jet behavior and calculated wall shear rates. Vertical and horizontal model orientations are compared, both with a beat rate of 75, outlet pressures of 90/60 mmHg and a flow rate of 1.3 l/min. The results show a significant change of the inlet jet behavior and the development of a rotational flow pattern. Vertically, the inlet jet is strong along the wall. It initiates a rotational flow pattern with a wandering axis of rotation. In contrast, the horizontal model orientation results show a weaker inlet jet along the wall with a nearly constant center of rotation location, which can be correlated to a higher risk of thrombotic events. In addition high speed videography illustrates differences in the diaphragm motion during diastole. Diaphragm opening trajectories measurements determine no significant impact of the density of the blood analog fluids. Hence, the results correlate to human blood. PMID:22929894

  7. Investigations of groundwater system and simulation of regional groundwater flow for North Penn Area 7 Superfund site, Montgomery County, Pennsylvania

    USGS Publications Warehouse

    Senior, Lisa A.; Goode, Daniel J.

    2013-01-01

    Groundwater in the vicinity of several industrial facilities in Upper Gwynedd Township and vicinity, Montgomery County, in southeast Pennsylvania has been shown to be contaminated with volatile organic compounds (VOCs), the most common of which is the solvent trichloroethylene (TCE). The 2-square-mile area was placed on the National Priorities List as the North Penn Area 7 Superfund site by the U.S. Environmental Protection Agency (USEPA) in 1989. The U.S. Geological Survey (USGS) conducted geophysical logging, aquifer testing, and water-level monitoring, and measured streamflows in and near North Penn Area 7 from fall 2000 through fall 2006 in a technical assistance study for the USEPA to develop an understanding of the hydrogeologic framework in the area as part of the USEPA Remedial Investigation. In addition, the USGS developed a groundwater-flow computer model based on the hydrogeologic framework to simulate regional groundwater flow and to estimate directions of groundwater flow and pathways of groundwater contaminants. The study area is underlain by Triassic- and Jurassic-age sandstones and shales of the Lockatong Formation and Brunswick Group in the Mesozoic Newark Basin. Regionally, these rocks strike northeast and dip to the northwest. The sequence of rocks form a fractured-sedimentary-rock aquifer that acts as a set of confined to partially confined layers of differing permeabilities. Depth to competent bedrock typically is less than 20 ft below land surface. The aquifer layers are recharged locally by precipitation and discharge locally to streams. The general configuration of the potentiometric surface in the aquifer is similar to topography, except in areas affected by pumping. The headwaters of Wissahickon Creek are nearby, and the stream flows southwest, parallel to strike, to bisect North Penn Area 7. Groundwater is pumped in the vicinity of North Penn Area 7 for industrial use, public supply, and residential supply. Results of field investigations

  8. FEASIBILITY ANALYSIS FOR INSTALLING A CIRCULATING FLUIDIZED BED BOILER FOR COFIRING MULTIPLE BIOFUELS AND OTHER WASTES WITH COAL AT PENN STATE UNIVERSITY

    SciTech Connect

    Bruce G. Miller; Sharon Falcone Miller; Robert Cooper; Douglas Donovan; John Gaudlip; Matthew Lapinsky; William Serencsits; Neil Raskin; Dale Lamke

    2001-07-13

    The Pennsylvania State University, under contract to the U.S. Department of Energy, National Energy Technology Laboratory is performing a feasibility analysis on installing a state-of-the-art circulating fluidized bed boiler and ceramic filter emission control device at Penn State's University Park campus for cofiring multiple biofuels and other wastes with coal, and developing a test program to evaluate cofiring multiple biofuels and coal-based feedstocks. The objective of the project is being accomplished using a team that includes personnel from Penn State's Energy Institute, Office of Physical Plant, and College of Agricultural Sciences, Foster Wheeler Energy Services, Inc., Parsons Energy and Chemicals Group, Inc., and Cofiring Alternatives. During this reporting period, work focused on completing the biofuel characterization and the design of the conceptual fluidized bed system.

  9. FEASIBILITY ANALYSIS FOR INSTALLING A CIRCULATING FLUIDIZED BED BOILER FOR COFIRING MULTIPLE BIOFUELS AND OTHER WASTES WITH COAL AT PENN STATE UNIVERSITY

    SciTech Connect

    Bruce G. Miller; Curtis Jawdy

    2000-10-09

    The Pennsylvania State University, under contract to the US Department of Energy, National Energy Technology Laboratory is performing a feasibility analysis on installing a state-of-the-art circulating fluidized bed boiler and ceramic filter emission control device at Penn State's University Park campus for cofiring multiple biofuels and other wastes with coal or coal refuse, and developing a test program to evaluate cofiring multiple biofuels and coal-based feedstocks. The objective of the project is being accomplished using a team that includes personnel from Penn State's Energy Institute and the Office of Physical Plant, Foster Wheeler Energy Corporation, Foster Wheeler Development Corporation, and Cofiring Alternatives. The major emphasis of work during this reporting period was to assess the types and quantities of potential feedstocks and collect samples of them for analysis. Approximately twenty different biomass, animal waste, and other wastes were collected and analyzed.

  10. FEASIBILITY ANALYSIS FOR INSTALLING A CIRCULATING FLUIDIZED BED BOILER FOR COFIRING MULTIPLE BIOFUELS AND OTHER WASTES WITH COAL AT PENN STATE UNIVERSITY

    SciTech Connect

    Bruce G. Miller; Sharon Falcone Miller; Robert Cooper; Douglas Donovan; John Gaudlip; Matthew Lapinsky; William Serencsits

    2001-01-18

    The Pennsylvania State University, under contract to the U.S. Department of Energy, National Energy Technology Laboratory is performing a feasibility analysis on installing a state-of-the-art circulating fluidized bed boiler and ceramic filter emission control device at Penn State's University Park campus for cofiring multiple biofuels and other wastes with coal, and developing a test program to evaluate cofiring multiple biofuels and coal-based feedstocks. The objective of the project is being accomplished using a team that includes personnel from Penn State's Energy Institute, Office of Physical Plant, and College of Agricultural Sciences; Foster Wheeler Energy Services, Inc.; Parsons Energy and Chemicals Group, Inc.; and Cofiring Alternatives. During this reporting period, work focused on performing the design of the conceptual fluidized bed system and determining the system economics.

  11. Genetics Home Reference: Meier-Gorlin syndrome

    MedlinePlus

    ... stature. It is considered a form of primordial dwarfism because the growth problems begin before birth (intrauterine ... Resources MedlinePlus (2 links) Encyclopedia: Microcephaly Health Topic: Dwarfism Genetic and Rare Diseases Information Center (1 link) ...

  12. FEASIBILITY ANALYSIS FOR INSTALLING A CIRCULATING FLUIDIZED BED BOILER FOR COFIRING MULTIPLE BIOFUELS AND OTHER WASTES WITH COAL AT PENN STATE UNIVERSITY

    SciTech Connect

    Bruce G. Miller; Sharon Falcone Miller; Robert Cooper; Douglas Donovan; John Gaudlip; Matthew Lapinsky; William Serencsits; Neil Raskin; Dale Lamke

    2001-10-12

    The Pennsylvania State University, under contract to the U.S. Department of Energy (DOE), National Energy Technology Laboratory (NETL) is performing a feasibility analysis on installing a state-of-the-art circulating fluidized bed (CFB) boiler and ceramic filter emission control device at Penn State's University Park campus for cofiring multiple biofuels and other wastes with coal, and developing a test program to evaluate cofiring multiple biofuels and coal-based feedstocks. Penn State currently operates an aging stoker-fired steam plant at its University Park campus and has spent considerable resources over the last ten to fifteen years investigating boiler replacements and performing life extension studies. This effort, in combination with a variety of agricultural and other wastes generated at the agricultural-based university and the surrounding rural community, has led Penn State to assemble a team of fluidized bed and cofiring experts to assess the feasibility of installing a CFB boiler for cofiring biomass and other wastes along with coal-based fuels.

  13. Validation of the Penn Inventory of Scrupulosity (PIOS) in scrupulous and nonscrupulous patients: Revision of factor structure and psychometrics.

    PubMed

    Huppert, Jonathan D; Fradkin, Isaac

    2016-06-01

    Scrupulosity, or obsessive-compulsive symptoms related to religiosity or religion, is a common presentation of obsessive compulsive disorder (OCD), and it is important to elucidate its phenomenology and measurement. Today, the most widespread questionnaire for the assessment of scrupulosity is the Penn Inventory of Scrupulosity (PIOS). The current study examines the psychometric properties of the PIOS in outpatient, treatment-seeking patients. Results of a confirmatory factor analysis suggested an unsatisfactory fit for previously suggested factor structures. A follow-up exploratory factor analysis suggested that a bifactor model was the most suitable solution. In addition, the scores of the PIOS and its revised subscales were found to have moderate-good concurrent validity; however, its scores discriminated poorly between patients with scrupulous obsessions and patients with OCD and other repugnant obsessions. Group differences and receiver operating characteristics (ROC) analyses both indicated that the PIOS is more suitable in discriminating scrupulous obsessions in Christian patients but not in other religious groups (i.e., Jews, nonreligious patients). Additional analyses revealed that the co-occurrence of scrupulous and other repugnant obsessions is also moderated by religious affiliation. These results raise questions in terms of grouping scrupulosity with other repugnant obsessions and suggest for the need of culturally sensitive instruments of scrupulosity. (PsycINFO Database Record PMID:26372375

  14. In vivo performance of a transcutaneous energy transmission system with the Penn State motor driven ventricular assist device.

    PubMed

    Weiss, W J; Rosenberg, G; Snyder, A J; Pae, W E; Richenbacher, W E; Pierce, W S

    1989-01-01

    A transcutaneous energy transmission system (TETS) has been used to power the Penn State motor driven ventricular assist device in nine calf experiments, for a total of 316 days of cumulative in vivo experience. This is seen as an important step toward a completely implantable ventricular assist system and total artificial heart. The TETS converts an external 12 volt DC source via inductive coupling to a regulated 14 volt output voltage for use by the motor controller. A maximum output power of 70 watts is available. In calf experiments, the TETS output power averaged between 8 and 12 watts. The motor controller was not implanted in these experiments, awaiting further development of the miniaturized electronics. The TETS output was returned percutaneously to the external motor controller, allowing the TETS output to be monitored directly. System efficiency, from DC source to DC output, and including losses in 12 feet of cable, ranged from 55% to 70%, depending upon supply voltage, motor load, and degree of coil coupling. The subcutaneous coil was well tolerated, demonstrating only temporary, mild, superficial induration. PMID:2597465

  15. Flow visualization of three-dimensionality inside the 12 cc Penn State pulsatile pediatric ventricular assist device.

    PubMed

    Roszelle, Breigh N; Deutsch, Steven; Manning, Keefe B

    2010-02-01

    In order to aid the ongoing concern of limited organ availability for pediatric heart transplants, Penn State has continued development of a pulsatile Pediatric Ventricular Assist Device (PVAD). Initial studies of the PVAD observed an increase in thrombus formation due to differences in flow field physics when compared to adult sized devices, which included a higher degree of three-dimensionality. This unique flow field brings into question the use of 2D planar particle image velocimetry (PIV) as a flow visualization technique, however the small size and high curvature of the PVAD make other tools such as stereoscopic PIV impractical. In order to test the reliability of the 2D results, we perform a pseudo-3D PIV study using planes both parallel and normal to the diaphragm employing a mock circulatory loop containing a viscoelastic fluid that mimics 40% hematocrit blood. We find that while the third component of velocity is extremely helpful to a physical understanding of the flow, particularly of the diastolic jet and the development of a desired rotational pattern, the flow data taken parallel to the diaphragm is sufficient to describe the wall shear rates, a critical aspect to the study of thrombosis and design of such pumps. PMID:19936926

  16. Psychometric properties of a brief version of the Penn State Worry Questionnaire in African Americans and European Americans.

    PubMed

    DeLapp, Ryan C T; Chapman, L Kevin; Williams, Monnica T

    2016-05-01

    The reliable and valid assessment of chronic worry in African Americans is vital when attempting to draw cross-cultural comparisons between African Americans and other ethnic groups. As such, the current study examined the psychometric properties of a brief version of a gold standard assessment of chronic worry, specifically the Penn State Worry Questionnaire-Abbreviated (PSWQ-A; Hopko et al., 2003) in a college sample of African Americans (n = 100) and European Americans (n = 121). Results indicated that the PSWQ-A total score has good internal consistency and convergent validity with another measure of anxiety, but less than favorable discriminant validity with a measure of depression in African American and European American students. Also, the 1-factor solution for the 8-item PSWQ-A had excellent model fit in our full sample and was partially invariant between ethnic groups. Collectively, the present study provides evidence that the PSWQ-A is a psychometrically sound option for assessing chronic worry and suggests that this brief measure may enhance the time efficiency and clinical utility of research and clinical assessments in ethnically diverse samples. (PsycINFO Database Record PMID:26375429

  17. Geochemical and mineralogical controls on trace element release from the Penn Mine base-metal slag dump, California

    USGS Publications Warehouse

    Parsons, M.B.; Bird, D.K.; Einaudi, M.T.; Alpers, C.N.

    2001-01-01

    Base-metal slag deposits at the Penn Mine in Calaveras County, California, are a source of environmental contamination through leaching of potentially toxic elements. Historical Cu smelting at Penn Mine (1865-1919) generated approximately 200,000 m3 of slag. The slag deposits, which are flooded annually by a reservoir used for drinking water and irrigation, also may be in contact with acidic ground waters (pH < 4) from the adjacent mine area. Slags vary from grey to black, are glassy to crystalline, and range in size from coarse sand to large (0.6 ?? 0.7 ?? 1.5 m), tub-shaped casts. Metals are hosted by a variety of minerals and two glass phases. On the basis of mineralogy, slags are characterized by 4 main types: fayalite-rich, glassy, willemite-rich, and sulfide-rich. The ranges in metal and metalloid concentrations of 17 slag samples are: As, 0.0004-0.92; Ba, 0.13-2.9; Cd, 0.0014-1.4; Cu, 0.18-6.4; Pb, 0.02-11; and Zn, 3.2-28 wt.%. Leachates from Toxicity Characteristic Leaching Procedure tests (acetic acid buffered at pH 4.93) on two wiltemite-rich slags contained Cd and Pb concentrations (up to 2.5 and 30 mg/l, respectively) in excess of US Environmental Protection Agency (USEPA) regulatory limits. Analyses of filtered (0.45 ??m) water, collected within the flooded slag dump during reservoir drawdown, reveal concentrations of Cd (1.7 ??g/l), Cu (35 ??g/l), and Zn (250 ??g/l) that exceed USEPA chronic toxicity guidelines for the protection of aquatic life. Data from field and laboratory studies were used to develop geochemical models with the program EQ3/6 that simulate irreversible mass-transfer between slag deposits and reservoir waters. These models include kinetic rate laws for abiotic sulfide oxidation and surface-controlled dissolution of silicates, oxides, and glass. Calculations demonstrate that the main processes controlling dissolved metal concentrations are (1) dissolution of fayalite, willemite, and glass; (2) sulfide oxidation; and (3) secondary

  18. Acetabular revision with impaction bone grafting and a cemented polyethylene acetabular component: comparison of the Kaplan-Meier analysis to the competing risk analysis in 62 revisions with 25 to 30 years follow-up.

    PubMed

    Te Stroet, M A J; Keurentjes, J C; Rijnen, W H C; Gardeniers, J W M; Verdonschot, N; Slooff, T J J H; Schreurs, B W

    2015-10-01

    We present the results of 62 consecutive acetabular revisions using impaction bone grafting and a cemented polyethylene acetabular component in 58 patients (13 men and 45 women) after a mean follow-up of 27 years (25 to 30). All patients were prospectively followed. The mean age at revision was 59.2 years (23 to 82). We performed Kaplan-Meier (KM) analysis and also a Competing Risk (CR) analysis because with long-term follow-up, the presence of a competing event (i.e. death) prevents the occurrence of the endpoint of re-revision. A total of 48 patients (52 hips) had died or had been re-revised at final review in March 2011. None of the deaths were related to the surgery. The mean Harris hip score of the ten surviving hips in ten patients was 76 points (45 to 99). The KM survivorship at 25 years for the endpoint 're-revision for any reason' was 58.0% (95% confidence interval (CI) 38 to 73) and for 're-revision for aseptic loosening' 72.1% (95% CI 51 to 85). With the CR analysis we calculated the KM analysis overestimates the failure rate with respectively 74% and 93% for these endpoints. The current study shows that acetabular impaction bone grafting revisions provide good clinical results at over 25 years. PMID:26430007

  19. The identification, characterization and optimization of small molecule probes of cysteine proteases: experiences of the Penn Center for Molecular Discovery with cathepsin B and cathepsin L.

    PubMed

    Huryn, Donna M; Smith, Amos B

    2009-01-01

    During the pilot phase of the NIH Molecular Library Screening Network, the Penn Center for Molecular Discovery focused on a series of projects aimed at high throughput screening and the development of probes of a variety of protease targets. This review provides our medicinal chemistry experience with two such targets--cathepsin B and cathepsin L. We describe our approach for hit validation, characterization and triage that led to a critical understanding of the nature of hits from the cathepsin B project. In addition, we detail our experience at hit identification and optimization that led to the development of a novel thiocarbazate probe of cathepsin L. PMID:19807666

  20. Metabolic syndrome burden in apparently healthy adolescents are adversely associated with cardiac autonomic modulation- Penn State Children Cohort

    PubMed Central

    Rodríguez-Colón, Sol M.; He, Fan; Bixler, Edward O.; Fernandez-Mendoza, Julio; Vgontzas, Alexandros N.; Calhoun, Susan; Zheng, Zhi-Jie; Liao, Duanping

    2015-01-01

    Background Reduced cardiac autonomic modulation (CAM) has been associated with metabolic syndrome (MetS) in adults. However, the association between MetS component cluster and CAM has not been examined in adolescents. Methods We conducted a cross-sectional analysis using data from the Penn State Child Cohort follow-up examination. CAM was assessed by heart rate variability (HRV) analysis of 39-hour RR intervals, including frequency (high frequency, HF; low frequency, LF; and LF/HF ratio) and time (SDNN, standard deviation of all RR intervals; RMSSD, square root of the mean of the sum of the squares of differences between adjacent RR intervals; and HR, heart rate) domain variables. To assess the MetS burden, we used continuous MetS score (cMetS)–sum of the age and sex-adjusted standardized residual (Z-score) of five established MetS components. Linear mixed-effect models were used to analyze the association between cMetS and CAM in the entire population and stratified by gender. Results After adjusting for age, sex, and race, cMetS was significantly associated with reduced HRV and higher HR. With 1 standard deviation increase in cMetS, there was a significant decrease in HF(−0.10(SE=0.02)), LF(−0.07(SE=0.01)), SDNN(−1.97(SE=0.50)), and RMSSD(−1.70(SE=0.72)), and increase in LF/HF(0.08(SE=0.02)) and HR(1.40(SE=0.26)). All cMetS components, with the exception of high-density lipoprotein (HDL), were associated with significantly decreased HRV and increased HR. High blood pressure (MAP) and triglyceride (TG) levels were also associated with an increase in LF/HF and decrease in RMSSD. An increase in high-density lipoprotein was only associated with higher LF and SDNN. Moreover, cMetS and HRV associations were more pronounced in males than in females. The associations between HRV and. MAP, TG, and HDL were more pronounced in females. Conclusions cMetS score is associated with lower HRV, suggesting an adverse impact on CAM, even in apparently healthy adolescents

  1. 'PACS at Penn'

    NASA Astrophysics Data System (ADS)

    Arenson, Ronald L.; Seshadri, Sridhar B.; Kundel, Harold L.; DeSimone, Debra

    1989-05-01

    History: Our experience with Medical Image Management Systems (MIMS, also called PACS) began in 1982 with the creation of a digital subtraction angiography (DSA) unit. This DSA system was built utilizing a DeAnza image array processor with boards fabricated by our staff to interface with a Siemens angiography room. Because of the need to transmit and eventually store very large image files on a remote computer, we designed and fabricated a point-to-point fiber-optic link [82-ARENA. This device was later marketed by Canoga Systems and was an important contribution to the design of commercial fiber-optic networks. Recognizing the importance of a versatile Radiology Information System (RIS) and its critical inter-relationship to a MIMS, some very early work on RIS design was carried out [79-ARENA, [79.B-AREN ], [84-AREN ].

  2. The Penn Polarimeters

    NASA Astrophysics Data System (ADS)

    Koch, Robert H.; Wolf, George W.; Hull, Anthony B.; Elias, Nicholas M., II; Holenstein, Bruce D.; Mitchell, Richard J.

    2012-03-01

    This report describes the inception, development and extensive use over 30 years of elliptical polarimeters at the University of Pennsylvania. The initial Mark I polarimeter design utilized oriented retarder plates and a calcite Foster-Clarke prism as the analyzer. The Mark I polarimeter was used on the Kitt Peak 0.9 m in 1969-70 to accomplish a survey of approximately 70 objects before the device was relocated to the 0.72 m reflector at the Flower and Cook Observatory. Successive generations of automation and improvements included the early-80's optical redesign to utilize a photoelastic modulated wave plate and an Ithaco lock-in amplifier - the photoelastic modulating polarimeter. The final design in 2000 concluded with a fully remote operable device. The legacy of the polarimetric programs includes studies of close binaries, pulsating hot stars, and luminous late-type variables.

  3. FEASIBILITY ANALYSIS FOR INSTALLING A CIRCULATING FLUIDIZED BED BOILER FOR COFIRING MULTIPLE BIOFUELS AND OTHER WASTES WITH COAL AT PENN STATE UNIVERSITY

    SciTech Connect

    Bruce G. Miller; Sharon Falcone Miller; Robert Cooper; John Gaudlip; Matthew Lapinsky; Rhett McLaren; William Serencsits; Neil Raskin; Tom Steitz; Joseph J. Battista

    2003-03-26

    The Pennsylvania State University, utilizing funds furnished by the U.S. Department of Energy's Biomass Power Program, investigated the installation of a state-of-the-art circulating fluidized bed boiler at Penn State's University Park campus for cofiring multiple biofuels and other wastes with coal, and developing a test program to evaluate cofiring biofuels and coal-based feedstocks. The study was performed using a team that included personnel from Penn State's Energy Institute, Office of Physical Plant, and College of Agricultural Sciences; Foster Wheeler Energy Services, Inc.; Foster Wheeler Energy Corporation; Parsons Energy and Chemicals Group, Inc.; and Cofiring Alternatives. The activities included assessing potential feedstocks at the University Park campus and surrounding region with an emphasis on biomass materials, collecting and analyzing potential feedstocks, assessing agglomeration, deposition, and corrosion tendencies, identifying the optimum location for the boiler system through an internal site selection process, performing a three circulating fluidized bed (CFB) boiler design and a 15-year boiler plant transition plan, determining the costs associated with installing the boiler system, developing a preliminary test program, determining the associated costs for the test program, and exploring potential emissions credits when using the biomass CFB boiler.

  4. The Influence of Operational Protocol on the Fluid Dynamics in the 12 cc Penn State Pulsatile Pediatric Ventricular Assist Device: The Effect of End-Diastolic Delay

    PubMed Central

    Cooper, Benjamin T.; Roszelle, Breigh N.; Long, Tobias C.; Deutsch, Steven; Manning, Keefe B.

    2009-01-01

    The success of adult ventricular assist devices (VADs), coupled with the high transplant waiting list mortality of infants (40 %) has prompted Penn State to develop a pediatric version of the clinically successful adult device. While the primary use of this device will be bridge-to-transplant, there has been sufficient clinical data to demonstrate the efficacy of VADs in a bridge-to-recovery setting. However, removing the patient from the device, a process known as weaning, demands operation of the device at a lower beat rate and concomitant increased risk for thromboembolism. Previous studies have shown that the interrelated flow characteristics necessary for the prevention of thrombosis in a pulsatile VAD are a strong inlet jet, a late diastolic recirculating flow, and a wall shear rate greater than 500 s−1. In an effort to develop a strong inlet jet and rotational flow pattern at a lower beat and flow rate; we have compressed diastole by altering the end-diastolic delay time (EDD). Particle image velocimetry was used to compare the flow fields and wall shear rates in the chamber of the 12 cc Penn State pulsatile pediatric VAD operated at 50 beats per minute using EDDs of 10, 50, and 100 ms. While we expected the 100 ms end-diastolic delay to have the best wall shear profiles, we found that the 50 ms EDD condition was superior to both the 10 and 100 EDD conditions, due to a longer sustained inlet jet. PMID:20420603

  5. Geophysical Logs, Aquifer Tests, and Water Levels in Wells in and Near the North Penn Area 7 Superfund Site, Upper Gwynedd Township, Montgomery County, Pennsylvania, 2002-2006

    USGS Publications Warehouse

    Senior, Lisa A.; Conger, Randall W.; Bird, Philip H.

    2008-01-01

    Ground water in the vicinity of several industrial facilities in Upper Gwynedd Township and Lansdale Borough, Montgomery County, Pa., is contaminated with several volatile organic compounds (VOCs). The 2-square-mile area was placed on the National Priorities List as the North Penn Area 7 Superfund Site by the U.S. Environmental Protection Agency (USEPA) in 1989. The U.S. Geological Survey (USGS) conducted geophysical logging, aquifer testing, water-level monitoring, and streamflow measurements in the vicinity of North Penn Area 7 from October 2002 through December 2006. This followed work that began in 2000 to assist the USEPA in developing an understanding of the hydrogeologic framework in the area as part of the USEPA Remedial Investigation. The study area is underlain by Triassic- and Jurassic-age sandstones, siltstones, and shales of the Lockatong Formation and the Brunswick Group. Regionally, these rocks strike northeast and dip to the northwest. The sequence of rocks form fractured-rock aquifers that act as a set of confined to semi-confined layered aquifers of differing permeabilities. The aquifers are recharged by precipitation and discharge to streams and wells. The Wissahickon Creek headwaters are less than 1 mile northeast of the study area. This stream flows southwest approximately parallel to strike and bisects North Penn Area 7. Ground water is pumped in the vicinity of North Penn Area 7 for industrial use and public supply. The USGS collected geophysical logs for 42 wells that ranged in depth from 40 to 477 ft. Aquifer-interval-isolation testing was done in 17 of the 42 wells, for a total of 122 zones tested. A multiple-well aquifer test was conducted by monitoring the response of 14 wells to pumping and shutdown of a 600-ft deep production well in November-December 2004. In addition, water levels were monitored continuously in four wells in the area from October 2002 through September 2006, and streamflow was measured quarterly at two sites on

  6. Calculations of electron stopping powers for 41 elemental solids over the 50 eV to 30 keV range with the full Penn algorithm

    NASA Astrophysics Data System (ADS)

    Shinotsuka, H.; Tanuma, S.; Powell, C. J.; Penn, D. R.

    2012-01-01

    We present mass collision electron stopping powers (SPs) for 41 elemental solids (Li, Be, graphite, diamond, glassy C, Na, Mg, Al, Si, K, Sc, Ti, V, Cr, Fe, Co, Ni, Cu, Ge, Y, Nb, Mo, Ru, Rh, Pd, Ag, In, Sn, Cs, Gd, Tb, Dy, Hf, Ta, W, Re, Os, Ir, Pt, Au, and Bi) that were calculated from experimental energy-loss-function data with the full Penn algorithm for electron energies between 50 eV and 30 keV. Improved sets of energy-loss functions were used for 19 solids. Comparisons were made of these SPs with SPs calculated with the single-pole approximation, previous SP calculations, and experimental SPs. Generally satisfactory agreement was found with SPs from the single-pole approximation for energies above 100 eV, with other calculated SPs, and with measured SPs.

  7. Public health assessment for north Penn-area 1, Souderton, Montgomery County, Pennsylvania, Region 3. Cerclis No. PAD096834494. Final report

    SciTech Connect

    Not Available

    1994-01-12

    The North Penn Area 1 site, a National Priorities List (NPL) site, is located in the Borough of Souderton, Montgomery County, Pennsylvania. Gentle, Cleaners, Inc., one of the parties potentially responsible for the site contamination, has been in business since 1953 and used tetrachloroethene (PCE) from 1953 to 1983 in dry cleaning operations. At present, groundwater is the only medium that is known to be contaminated. Enviromental data for surface soil, surface water, sediment, and air do not exist. Past, present, and future completed exposure pathways for volatile organic compounds such as PCE and TCE in groundwater exist for nearby residents. The site is considered an indeterminate public health hazard because limited data are available; however, data that are available do not indicate that humans are being or have been exposed to levels of contaminants that would be expected to cause any adverse health effects.

  8. Hydrogeology and geochemistry of acid mine drainage in ground water in the vicinity of Penn Mine and Camanche Reservoir, Calaveras County, California; first-year summary

    USGS Publications Warehouse

    Hamlin, S.N.; Alpers, C.N.

    1995-01-01

    Acid drainage from the Penn Mine in Calaveras County, California, has caused contamination of ground water between Mine Run Dam and Camanche Reservoir. The Penn Mine was first developed in the 1860's primarily for copper and later produced lesser amounts of zinc, lead, silver, and gold from steeply dipping massive sulfide lenses in metamorphic rocks. Surface disposal of sulfidic waste rock and tailings from mine operations has produced acidic drainage with pH values between 2.3 and 2.7 and elevated concentrations of sulfate and metals, including copper, zinc, cadmium, iron, and aluminum. During the mine's operation and after its subsequent abandonment in the late 1950's, acid mine drainage flowed down Mine Run into the Mokelumne River. Construction of Camanche Dam in 1963 flooded part of the Mokelumne River adjacent to Penn Mine. Surface-water diversions and unlined impoundments were constructed at Penn Mine in 1979 to reduce runoff from the mine, collect contaminated surface water, and enhance evaporation. Some of the contaminated surface water infiltrates the ground water and flows toward Camanche Reservoir. Ground- water flow in the study area is controlled by the local hydraulic gradient and the hydraulic characteristics of two principal rock types, a Jurassic metavolcanic unit and the underlying Salt Spring slate. The hydraulic gradient is west from Mine Run impoundment toward Camanche Reservoir. The median hydraulic conductivity was about 10 to 50 times higher in the metavolcanic rock (0.1 foot per day) than in the slate (0.002 to 0.01 foot per day); most flow occurs in the metavolcanic rock where hydraulic conductivity is as high as 50 feet per day in two locations. The contact between the two rock units is a fault plane that strikes N20?W, dips 20?NE, and is a likely conduit for ground-water flow, based on down-hole measurements with a heatpulse flowmeter. Analyses of water samples collected during April 1992 provide a comprehensive characterization of

  9. Altitude and configuration of the potentiometric surface in the Upper Triassic sedimentary rocks at and near the North Penn Area 12 Superfund site, Worcester Township, Montgomery County, Pennsylvania, July 20-27, 1995

    USGS Publications Warehouse

    Grazul, Kevin E.

    1996-01-01

    A map showing the altitude of the potentiometric surface defined by measured water levels near the North Penn Area 12 Superfund Site in Worcester Township, Montgomery County, Pa., was constructed from water levels measured in 35 wells from July 20-27, 1995. Observed water-level altitudes range from 435 feet above sea level in a well near Church Road to 261 feet above sea level in a well near Land Road in Worcester Township.

  10. Parallel Psychometric and Cognitive Modeling Analyses of the Penn Face Memory Test in the Army Study to Assess Risk and Resilience in Service Members

    PubMed Central

    Thomas, Michael L.; Brown, Gregory G.; Gur, Ruben C.; Hansen, John A.; Nock, Matthew K.; Heeringa, Steven; Ursano, Robert J.; Stein, Murray B.

    2013-01-01

    Objective The psychometric properties of the Penn Face Memory Test (PFMT; Gur et al., 1997) were investigated in a large sample (4,236 participants) of U.S. Army Soldiers undergoing computerized neurocognitive testing. Data were drawn from the initial phase of the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS), a large-scale study directed towards identifying risk and resilience factors for suicidal behavior and other stress-related disorders in Army Soldiers. In this paper we report parallel psychometric and cognitive modeling analyses of the PFMT to determine whether ability estimates derived from the measure are precise and valid indicators of memory in the Army STARRS sample. Method Single-sample cross-validation methodology combined with exploratory factor and multidimensional item response theory techniques were used to explore the latent structure of the PFMT. To help resolve rotational indeterminacy of the exploratory solution, latent constructs were aligned with parameter estimates derived from an unequal-variance signal detection model. Results Analyses suggest that the PFMT measures two distinct latent constructs, one associated with memory strength and one associated with response bias, and that test scores are generally precise indicators of ability for the majority of Army STARRS participants. Conclusions These findings support the use of the PFMT as a measure of major constructs related to recognition memory and have implications for further cognitive-psychometric model development. PMID:23383967

  11. Geophysical Logs, Specific Capacity, and Water Quality of Four Wells at Rogers Mechanical (former Tate Andale) Property, North Penn Area 6 Superfund Site, Lansdale, Pennsylvania, 2006-07

    USGS Publications Warehouse

    Senior, Lisa A.; Bird, Philip H.

    2010-01-01

    As part of technical assistance to the U.S. Environmental Protection Agency (USEPA) in the remediation of properties on the North Penn Area 6 Superfund Site in Lansdale, Pa., the U.S. Geological Survey (USGS) in 2006-07 collected data in four monitor wells at the Rogers Mechanical (former Tate Andale) property. During this period, USGS collected and analyzed borehole geophysical and video logs of three new monitor wells (Rogers 4, Rogers 5, and Rogers 6) ranging in depth from 80 to 180 feet, a borehole video log and additional heatpulse-flowmeter measurements (to quantify vertical borehole flow) in one existing 100-foot deep well (Rogers 3S), and water-level data during development of two wells (Rogers 5 and Rogers 6) to determine specific capacity. USGS also summarized results of passive-diffusion bag sampling for volatile organic compounds (VOCs) in the four wells. These data were intended to help understand the groundwater system and the distribution of VOC contaminants in groundwater at the property.

  12. Factor structure, reliability, and validity of the Penn State Worry Questionnaire: differences between African-American and White-American college students.

    PubMed

    Carter, Michele M; Sbrocco, Tracy; Miller, Oscar; Suchday, Sonia; Lewis, Evelyn L; Freedman, Rachel E K

    2005-01-01

    This study examined differences in the factor structure of the Penn State Worry Questionnaire (PSWQ) between African-American (n=181) and White-American (n=180) college students. Results from a confirmatory factor analysis indicated that the traditional single-factor solution did not provide the best fit for the data from either ethnic group. A multiple-group factor analysis indicated that underlying structure of Factor 1 was roughly equivalent between ethnic groups. Structure of Factor 2, however, differed between groups. Specifically, item 10 loaded on different factors for each group. In support of these analyses, an exploratory factor analyses (EFA) among White-American participants indicated the presence of a two-factor model while an EFA among African-Americans indicated the presence of three factors. Despite some overlap in the overall factor structure between ethnic groups, African-Americans scored significantly lower on the PSWQ than the White-American group. Furthermore, among African-Americans level of ethnic identity was negatively related to state and trait measures of anxiety, but unrelated to measures of depression and worry. PMID:16243633

  13. Health assessment for the Transicoil, Inc. (Zone 12) North Penn Area Site, Worchester, Pennsylvania, Region 3. CERCLIS No. PAD057152365. Preliminary report

    SciTech Connect

    Not Available

    1988-09-29

    The Transicoil Inc. (Zone 12) North Penn Area Site consists of a manufacturing site for DC and synchro electric motors for commercial and defense uses. An on-site underground storage tank was used for waste oil and hazardous substances. On-site cesspools were used for sanitary waste disposal. Identified contaminants of concern to data include trichloroethylene (TCE), 1,1,1-trichloroethane, tetrachloroethylene (PCE), cis-1,2-dichloroethylene, 1,1-dichloroethane, and 1,1-dichloroethylene in well water and TCE, PCE, and 1,1,1-trichloroethane in soil. The site is considered to be of potential public health concern because of the risk to human health caused by the possibility of exposure to hazardous substances via ingestion of contaminated groundwater, surface water, or other materials or of plants or animals which have accumulated contaminants from the site; contaminated soil ingestion by children; inhalation of compounds volatilized from contaminated groundwater during household uses, of contaminants volatilized from the site, or of contaminants carried in reentrained dust; and dermal contact with contaminated groundwater, surface water, soil, or other materials.

  14. Thermal hydraulic analysis of two-phase closed thermosyphon cooling system for new cold neutron source moderator of Breazeale research reactor at Penn State

    NASA Astrophysics Data System (ADS)

    Habte, Melaku

    A cold neutron source cooling system is required for the Penn State's next generation cold neutron source facility that can accommodate a variable heat load up to about ˜10W with operating temperature of about 28K. An existing cold neutron source cooling system operating at the University of Texas Cold Neutron Source (TCNS) facility failed to accommodate heat loads upwards of 4W with the moderator temperature reaching a maximum of 44K, which is the critical temperature for the operating fluid neon. The cooling system that was used in the TCNS cooling system was a two-phase closed thermosyphon with a reservoir (TPCTR). The reservoir containing neon gas is kept at room temperature. In this study a detailed thermal analysis of the fundamental operating principles of a TPCTR were carried out. A detailed parametric study of the various geometric and thermo-physical factors that affect the limits of the operational capacity of the TPCTR investigated. A CFD analysis is carried out in order to further refine the heat transfer analysis and understand the flow structure inside the thermosyphon and the two-phase nucleate boiling in the evaporator section of the thermosyphon. In order to help the new design, a variety of ways of increasing the operating range and heat removal capacity of the TPCTR cooling system were analyzed so that it can accommodate the anticipated heat load of 10W or more. It is found, for example, that doubling the pressure of the system will increase the capacity index zeta by 50% for a system with an initial fill ratio FR of 1. A decrease in cryorefrigeration performance angle increases the capacity index. For example taking the current condition of the TCNS system and reducing the angle from the current value of ˜700 by half (˜350) will increase the cooling power 300%. Finally based on detailed analytic and CFD analysis the best operating condition were proposed.

  15. Interpretation of geophysical logs, aquifer tests, and water levels in wells in and near the North Penn Area 7 Superfund site, Upper Gwynedd Township, Montgomery County, Pennsylvania, 2000-02

    USGS Publications Warehouse

    Senior, Lisa A.; Cinotto, Peter J.; Conger, Randall W.; Bird, Philip H.; Pracht, Karl A.

    2005-01-01

    Ground water in the vicinity of various industrial facilities in Upper Gwynedd Township and Lansdale Borough, Montgomery County, Pa., is contaminated with various volatile organic compounds (VOCs). The 2-square-mile area was placed on the National Priorities List as the North Penn Area 7 Superfund site by the U.S. Environmental Protection Agency (USEPA) in 1989. The U.S. Geological Survey (USGS) conducted geophysical logging, aquifer testing, water-level monitoring, and streamflow measurements in the vicinity of North Penn Area 7 beginning autumn 2000 to assist the USEPA in developing an understanding of the hydrogeologic framework in the area as part of the USEPA Remedial Investigation. The study area is underlain by Triassic and Jurassic-age sandstones, siltstones, and shales of the Lockatong Formation and the Brunswick Group. Regionally, these rocks strike northeast and dip to the northwest. The sequence of rocks form a fractured-sedimentary-rock aquifer that acts as a set of confined to partially confined layered aquifers of differing permeabilities. The aquifers are recharged by precipitation and discharge to streams and wells. The Wissahickon Creek headwaters are less than 1 mile northeast of the study area, and this stream flows southwest to bisect North Penn Area 7. Ground water is pumped in the vicinity of North Penn Area 7 for industrial use and public supply. The USGS collected geophysical logs for 16 wells that ranged in depth from 50 to 623 feet. Aquifer-interval-isolation testing was done in 9 of the 16 wells, for a total of 30 zones tested. A multiple-well aquifer test was conducted by monitoring the response of 14 wells to pumping a 600-ft deep production well in February and March 2002. In addition, water levels were monitored continuously in three wells in the area and streamflow was measured quarterly at two sites on Wissahickon Creek from December 2000 through September 2002. Geophysical logging identified water-bearing zones associated with

  16. Borehole geophysical logging and aquifer-isolation tests conducted in well MG-1693 at North Penn Area 5 Superfund Site near Colmar, Montgomery County, Pennsylvania

    USGS Publications Warehouse

    Bird, Philip H.

    2006-01-01

    Borehole geophysical logging and aquifer-isolation (packer) tests were conducted in well MG-1693 (NP-87) at the North Penn Area 5 Superfund Site near Colmar, Montgomery County, Pa. Objectives of the study were to identify the depth and yield of water-bearing zones, occurrence of vertical borehole flow, and effects of pumping on water levels in nearby wells. Caliper, natural-gamma, single-point-resistance, fluid-temperature, fluid-resistivity, heatpulse-flowmeter, and borehole-video logs were collected. Vertical borehole-fluid movement direction and rate were measured under nonpumping conditions. The suite of logs was used to locate water-bearing fractures, determine zones of vertical borehole-fluid movement, and select depths to set packers. Aquifer-isolation tests were conducted to sample discrete intervals and to determine specific capacities of water-bearing zones and effects of pumping individual zones on water levels in two nearby monitor wells. Specific capacities of isolated zones during aquifer-isolation tests ranged from 0.03 to 3.09 (gal/min)/ft (gallons per minute per foot). Fractures identified by borehole geophysical methods as water-producing or water-receiving zones produced water when isolated and pumped. Water enters the borehole primarily through high-angle fractures at 416 to 435 ft bls (feet below land surface) and 129 to 136 ft bls. Water exits the borehole through a high-angle fracture at 104 to 107 ft bls, a broken casing joint at 82 ft bls, and sometimes as artesian flow through the top of the well. Thirteen intervals were selected for aquifer-isolation testing, using a straddle-packer assembly. The specific capacity of interval 1 was 2.09 (gal/min)/ft. The specific capacities of intervals 2, 3, and 4 were similar: 0.27, 0.30, and 0.29 (gal/min)/ft,respectively. The specific capacities of intervals 5, 6, 7, 8, and 10 were similar: 0.03, 0.04, 0.09, 0.09, and 0.04 (gal/min)/ft,respectively. Intervals 9, 11, and 12 each showed a strong

  17. The Penn State - Toruń Centre for Astronomy Planet Search stars. II. Lithium abundance analysis of the red giant clump sample

    NASA Astrophysics Data System (ADS)

    Adamów, M.; Niedzielski, A.; Villaver, E.; Wolszczan, A.; Nowak, G.

    2014-09-01

    Context. Standard stellar evolution theory does not predict existence of Li-rich giant stars. Several mechanisms for Li-enrichment have been proposed to operate at certain locations inside some stars. The actual mechanism operating in real stars is still unknown. Aims: Using the sample of 348 stars from the Penn State - Toruń Centre for Astronomy Planet Search, for which uniformly determined atmospheric parameters are available, with chemical abundances and rotational velocities presented here, we investigate various channels of Li enrichment in giants. We also study Li-overabundant giants in more detail in search for origin of their peculiarities. Methods: Our work is based on the Hobby-Eberly Telescope spectra obtained with the High Resolution Spectrograph, which we use for determination of abundances and rotational velocities. The Li abundance was determined from the 7Li λ670.8 nm line, while we use a more extended set of lines for α-elements abundances. In a series of Kolmogorov-Smirnov tests, we compare Li-overabundant giants with other stars in the sample. We also use available IR photometric and kinematical data in search for evidence of mass-loss. We investigate properties of the most Li-abundant giants in more detail by using multi-epoch precise radial velocities. Results: We present Li and α-elements abundances, as well as rotational velocities for 348 stars. We detected Li in 92 stars, of which 82 are giants. Eleven of them show significant Li abundance A(Li)NLTE> 1.4 and seven of them are Li-overabundant objects, according to common criterion of A(Li) > 1.5 and their location on HR diagram, including TYC 0684-00553-1 and TYC 3105-00152-1, which are two giants with Li abundances close to meteoritic level. For another 271 stars, upper limits of Li abundance are presented. We confirmed three objects with increased stellar rotation. We show that Li-overabundant giants are among the most massive stars from our sample and show larger than average

  18. Modeling and design of a new core-moderator assembly and neutron beam ports for the Penn State Breazeale Nuclear Reactor (PSBR)

    NASA Astrophysics Data System (ADS)

    Ucar, Dundar

    This study is for modeling and designing a new reactor core-moderator assembly and new neutron beam ports that aimed to expand utilization of a new beam hall of the Penn State Breazeale Reactor (PSBR). The PSBR is a part of the Radiation Science and Engineering Facility (RSEC) and is a TRIGA MARK III type research reactor with a movable core placed in a large pool and is capable to produce 1MW output. This reactor is a pool-type reactor with pulsing capability up to 2000 MW for 10-20 msec. There are seven beam ports currently installed to the reactor. The PSBR's existing core design limits the experimental capability of the facility, as only two of the seven available neutron beam ports are usable. The finalized design features an optimized result in light of the data obtained from neutronic and thermal-hydraulics analyses as well as geometrical constraints. A new core-moderator assembly was introduced to overcome the limitations of the existing PSBR design, specifically maximizing number of available neutron beam ports and mitigating the hydrogen gamma contamination of the neutron beam channeled in the beam ports. A crescent-shaped moderator is favored in the new PSBR design since it enables simultaneous use of five new neutron beam ports in the facility. Furthermore, the crescent shape sanctions a coupling of the core and moderator, which reduces the hydrogen gamma contamination significantly in the new beam ports. A coupled MURE and MCNP5 code optimization analysis was performed to calculate the optimum design parameters for the new PSBR. Thermal-hydraulics analysis of the new design was achieved using ANSYS Fluent CFD code. In the current form, the PSBR is cooled by natural convection of the pool water. The driving force for the natural circulation of the fluid is the heat generation within the fuel rods. The convective heat data was generated at the reactor's different operating powers by using TRIGSIMS, the fuel management code of the PSBR core. In the CFD

  19. Evaluation of borehole geophysical logging, aquifer-isolation tests, distribution of contaminants, and water-level measurements at the North Penn Area 5 Superfund Site, Bucks and Montgomery counties, Pennsylvania

    USGS Publications Warehouse

    Bird, Philip H.; Conger, Randall W.

    2002-01-01

    Borehole geophysical logging and aquiferisolation (packer) tests were conducted at the North Penn Area 5 Superfund site in Bucks and Montgomery Counties, Pa. Caliper, naturalgamma, single-point-resistance, fluid-temperature, fluid-resistivity, heatpulse-flowmeter, and digital acoustic-televiewer logs and borehole television surveys were collected in 32 new and previously drilled wells that ranged in depth from 68 to 302 feet. Vertical borehole-fluid movement direction and rate were measured with a high-resolution heatpulse flowmeter under nonpumping conditions. The suite of logs was used to locate water-bearing fractures, determine zones of vertical borehole- fluid movement, select depths to set packers, and locate appropriate screen intervals for reconstructing new wells as monitoring wells. Aquifer-isolation tests were conducted in four wells to sample discrete intervals and to determine specific capacities of discrete water-bearing zones. Specific capacities of isolated zones during packer testing ranged from 0.12 to 15.30 gallons per minute per foot. Most fractures identified by borehole geophysical methods as water-producing or water-receiving zones produced water when isolated and pumped. The acoustic-televiewer logs define two basic fracture sets, bedding-plane partings with a mean strike of N. 62? E. and a mean dip of 27? NW., and high-angle fractures with a mean strike of N. 58? E. and a mean dip of 72? SE. Correlation of heatpulse-flowmeter data and acoustic-televiewer logs showed 83 percent of identified water-bearing fractures were high-angle fractures.

  20. Characterization of waste rock associated with acid drainage at the Penn Mine, California, by ground-based visible to short-wave infrared reflectance spectroscopy assisted by digital mapping

    USGS Publications Warehouse

    Montero, S.I.C.; Brimhall, G.H.; Alpers, C.N.; Swayze, G.A.

    2005-01-01

    Prior to remediation at the abandoned Cu-Zn Penn Mine in the Foothills massive sulfide belt of the Sierra Nevada, CA, acid mine drainage (AMD) was created, in part, by the subaerial oxidation of sulfides exposed on several waste piles. To support remediation efforts, a mineralogical study of the waste piles was undertaken by acquiring reflectance spectra (measured in the visible to short-wave infrared range of light (0.35-2.5 ??m) using a portable, digitally integrated pen tablet PC mapping system with differential global positioning system and laser rangefinder support. Analysis of the spectral data made use of a continuum removal and band-shape comparison method, and of reference spectral libraries of end-member minerals and mineral mixtures. Identification of secondary Fe-bearing minerals focused on band matching in the region between 0.43 and 1.3 ??m. Identification of sheet and other silicates was based on band-shape analysis in the region between 1.9 and 2.4 ??m. Analysis of reflectance spectra of characterized rock samples from the mine helped in gauging the spectral response to particle size and mixtures. The resulting mineral maps delineated a pattern of accumulation of secondary Fe minerals, wherein centers of copiapite and jarosite that formed at low pH (<3) were surrounded successively by goethite and hematite, which mark progressive increases in pH. This pattern represents the evolution of acid solutions discharged from the pyritic waste piles and the subsequent accumulation of secondary precipitates by hydrolysis reactions. The results highlight the high capacity of the pyritic waste to release further acid mine drainage into the environment, as well as the effectiveness of the mapping method to detect subtle changes in surface mineralogy and to produce maps useful to agencies responsible for remediating the site. ?? 2004 Elsevier B.V. All rights reserved.

  1. Penn State Scandal Encompasses Professors, Too

    ERIC Educational Resources Information Center

    Wilson, Robin

    2012-01-01

    While most of the national focus following charges of child sex abuse at Pennsylvania State University has centered on its coaches and administrators, the scandal has reached deep into the professoriate as well. Responding to constant questions has taken an emotional toll on the university's faculty members, who have been asked by neighbors,…

  2. LEXIS-NEXIS Instruction at Penn State.

    ERIC Educational Resources Information Center

    Stuart, Lynne M.; Harwell, Kevin R.

    1997-01-01

    Full-text services require more instruction and reference help than electronic bibliographic databases. To relieve pressure on reference staff, librarians at Pennsylvania State University developed weekly "Just-in-Time" demonstrations to help patrons learn how to use LEXIS-NEXIS. This article provides an overview of LEXIS-NEXIS and "Just-in-Time."…

  3. Stress, Neural Systems, and Genetic Code: An Interview with Neuroscientist Judy Cameron. Perspectives

    ERIC Educational Resources Information Center

    National Scientific Council on the Developing Child, 2006

    2006-01-01

    Research indicates some early life stresses can have a profound impact, resulting in changes in brain function and behavior, and even differences in the ways some genes express their particular genetic code signature. At various times during early development, different neural systems appear to have an increased sensitivity to stress and can…

  4. "Shake me up, Judy!": on Dickens, medicine and spinal cord disorders.

    PubMed

    Ohry, Avi

    2012-01-01

    Charles Dickens' ( 1812- 1870) works, were for a long time, a solid background for social, historical, psychological, literary and medical 19th century studies. In this article , some light is casted on Dickens, medicine and disabled people in his works, especially on paraplegics. PMID:23208940

  5. Altitude and Configuration of the Potentiometric Surface in the Upper White Clay Creek and Lower West Branch Brandywine Creek Basins including Portions of Penn, London Grove, New Garden, Londonderry, West Marlborough, Highland, and East Fallowfield Townships and West Grove, Avondale, Modena, and South Coatesville boroughs, Chester County, Pennsylvania, May through July 2006

    USGS Publications Warehouse

    Hale, Lindsay B.

    2007-01-01

    INTRODUCTION Since 1984, the U.S. Geological Survey (USGS) has been mapping the altitude and configuration of the potentiometric surface in Chester County as part of an ongoing cooperative program to measure and describe the water resources of the county. These maps can be used to determine the general direction of ground-water flow and are frequently referenced by municipalities and developers to evaluate ground-water conditions for water supply and resource-protection requirements. For this study, the potentiometric surface was mapped for an area in south-central Chester County. The northern part of the map includes portions of Highland, East Fallowfield, Londonderry, and West Marlborough Townships and South Coatesville and Modena Boroughs. The southern part of the map includes portions of Londonderry, West Marlborough, Penn, London Grove, and New Garden Townships and West Grove and Avondale Boroughs. The study area is mostly underlain by metamorphic rocks of the Glenarm Supergroup including Peters Creek Schist, Octoraro Phyllite, Wissahickon Schist, Cockeysville Mrable, and Setters Quartzite; and by pegmatite, mafic gneiss, felsic gneiss, and diabase. Ground water is obtained from these bedrock formations by wells that intercept fractures. The altitude and configuration of the potentiometric surface was contoured from water levels measured on different dates in available wells during May through July 2006 and from the altitude of springs and perennial streams. Topography was used as a guide for contouring so that the altitude of the potentiometric surface was inferred nowhere to be higher than the land surface. The potentiometric surface shown on this map is an approximation of the water table. The altitude of the actual potentiometric surface may differ from the water table, especially in areas where wells are completed in a semi-confined zone or have long open intervals that reflect the composite hydraulic head of multiple water-yielding fractures. A composite

  6. Building Resilience in Youth: The Penn Resiliency Program

    ERIC Educational Resources Information Center

    Reivich, Karen; Gillham, Jane

    2010-01-01

    Psychologists have been studying resilience since the 1970s to understand what enables individual to meet developmental milestones despite serious risk factors. Although early research used terms like "invincible" and "invulnerable" to describe youth who showed resilience, the current understanding is that resilience is enabled through ordinary…

  7. FCS Educators Benefit from Summer Program at Penn State

    ERIC Educational Resources Information Center

    Kinsey, Joanne; Sovich, Cynthia Rossi; Stanton, Jane; Sowers, Margaret

    2012-01-01

    The foundation and impetus for a sustained professional development program offering 44 graduate courses serving 641 FCS educators (approximately 50% returning participants) in Pennsylvania and the surrounding area were the six assumptions of Knowles related to the motivation of adult learners. Education researcher Malcolm Knowles asserts that…

  8. 3-D and the Penn reef play - recent experience

    SciTech Connect

    Nester, D.C. ); Erwin, G. ); Duncan, P.M. )

    1993-09-01

    Three-dimensional (3-D) seismic has driven a resurgence of the reef play in the Permian basin over the last two years. Surveys are being shot over 100 and 200 sections at a time, fueling what has become increasingly a land play. Drilling success ratios in excess of 80% are being claimed. Good wells are being made, sometimes within sight of a dry hole. This paper presents a methodology for the proper use of 3-D as an exploration tool with field examples taken from west Texas.

  9. Positron camera using position-sensitive detectors: PENN-PET

    SciTech Connect

    Muehllehner, G.; Karp, J.S.

    1986-01-01

    A single-slice positron camera has been developed with good spatial resolution and high count rate capability. The camera uses a hexagonal arrangement of six position-sensitive NaI(Tl) detectors. The count rate capability of NaI(Tl) was extended to 800k cps through the use of pulse shortening. In order to keep the detectors stationary, an iterative reconstruction algorithm was modified which ignores the missing data in the gaps between the six detectors and gives artifact-free images. The spatial resolution, as determined from the image of point sources in air, is 6.5 mm full width at half maximum. We have also imaged a brain phantom and dog hearts.

  10. Creating a Culture of Innovation at Penn State Outreach

    ERIC Educational Resources Information Center

    Weidemann, Craig D.

    2009-01-01

    From all sides, academia is being prodded to be ever more innovative. Not only are faculty expected to create knowledge from which solutions for our social, physical, and economic ills will spring, but all segments of the university must deal with new modes of communication, new business models, and even new ways of processing thought. This…

  11. New fuel management plan for the Penn State TRIGA

    SciTech Connect

    Hughes, D.; Boyle, P.; Levine, S.H.

    1996-12-31

    The Pennsylvania State University (PSU) Breazeale TRIGA has utilized 12 wt% U fuel in the core since July 1992, when six 12 wt% U fuel elements were loaded to replace the depleted 8.5 wt% U fuel in the centermost ring, the B ring. This reload increased the cold k{sub eff} from 1.03 to 1.05, the cold k{sub eff} of 1.03 being the minimum k{sub eff} that will permit 1-MW operation for a sustained period. In the next fuel reload, this 12 wt% U fuel is to be moved outward to the adjacent ring, the C ring, and six fresh 12 wt% U fuel elements are to be added to the B ring. It was determined that using the 12 wt% U in place of 8.5 wt% U fuel reduced fuel costs by a factor of 6, and continuing this use of six 12 wt% U fuel elements for each reload maintained the lower fuel costs. This reloading technique worked successfully, requiring only 26 additional 12 wt% U elements to be loaded into the core during the last 23 yr. Recently, however, a new instrumented 12 wt% U fuel element read much higher temperatures than all previous similar fuel elements. Its measured fuel temperature at 1 MW is 585{degrees}C. As a result, the PSU TRIGA now operates at or below 60% full power to prevent this element from reaching fuel temperatures well above 500{degrees}C. The purpose of this paper is to describe a new fuel management strategy developed to use 12 wt% U fuel, which permits 1-MW operation and limits the maximum fuel temperature to {approx}500{degrees}C.

  12. PENN PASS: a program for graduates of foreign dental schools.

    PubMed

    Berthold, P; Lopez, N

    1994-01-01

    An increasing number of graduates of foreign dental schools who enroll in advanced standing programs to qualify for licensure calls for dental schools to be prepared to handle not only the curricular demands but also the growing cultural diversity among its student population. The "reeducation" of this student group not only meets the need of foreign dentists for an American degree but may also provide health professionals to service various ethnic populations whose language and culture they are able to understand and identify with. A survey of students and graduates of a two-year Program for Advanced Standing Students (PASS) for graduates of foreign dental schools representing 34 countries aimed to arrive at an understanding of this student group through characterization of the foreign dentists and identification of their attitudes and feelings toward various aspects of the program, the school and faculty and their experience of stress. This report includes description of the distinctive features of the program which cater to specific needs and concerns of this non-traditional group of dental students. PASS students are accepted on the basis of their grades in dental school in home country, scores in the National Dental Board Examination Part I, Test of English as Foreign Language (TOEFL), and ratings in personal interviews. They complete an intensive summer program consisting of didactic and laboratory courses which prepares them for integration with four-year students for the last two years of didactic and clinical curriculum. Cultural diversity seminars, a special English class, PASS class meetings and seminars are unique additions to their program and aim to assist them adjust to the educational, social and cultural systems in an American school. Results of the survey show a majority of the PASS students feel that they are part of the school and that there is someone in the school whom they can approach for problems. An understanding of their ethnic and educational background is seen as a significant factor in their second basic dental education. Implications for education of foreign dental graduates amidst increasing diversification of the student body are discussed. PMID:7798405

  13. Reference Anytime Anywhere: Towards Virtual Reference Services at Penn State.

    ERIC Educational Resources Information Center

    Moyo, Lesley M.

    2002-01-01

    Outlines the service rationale, software and technology considerations taken by the Pennsylvania State University library in planning towards online, real-time reference services and provides an overview of the planned pilot project. Discusses recent trends in academic electronic libraries, including providing value-added services to support…

  14. Seeing the Forest for the Trees. Penn State Faculty Club

    ERIC Educational Resources Information Center

    Progressive Architecture, 1977

    1977-01-01

    The new faculty club at Pennsylvania State University designed by Venturi and Rauch, is praised for its siting, but criticized for the institutional colors of the interior and lack of accommodation to human needs. (MLF)

  15. From "Lawrence Kohlberg's Approach to Moral Education" by F. Clark Power, Ann Higgins, and Lawrence Kohlberg, with Judy Codding (1989)

    ERIC Educational Resources Information Center

    Schools: Studies in Education, 2011

    2011-01-01

    This article is an excerpt from "Lawrence Kohlberg's Approach to Moral Education." It refers several times to Kohlberg's "six stages of moral development." Stages 3 and 4 belong to the second level of moral development, which Kohlberg calls "conventional." At stage 3, one becomes aware of conventions as one sees what is right in terms of living up…

  16. A resolution congratulating the Penn State IFC/Panhellenic Dance Marathon on its continued success in support of the Four Diamonds Fund at Penn State Hershey Children's Hospital.

    THOMAS, 113th Congress

    Sen. Casey, Robert P., Jr. [D-PA

    2013-03-06

    03/06/2013 Referred to the Committee on the Judiciary. (text of measure as introduced: CR S1237) (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  17. A Review and Comparison of Methods for Recreating Individual Patient Data from Published Kaplan-Meier Survival Curves for Economic Evaluations: A Simulation Study

    PubMed Central

    Wan, Xiaomin; Peng, Liubao; Li, Yuanjian

    2015-01-01

    Background In general, the individual patient-level data (IPD) collected in clinical trials are not available to independent researchers to conduct economic evaluations; researchers only have access to published survival curves and summary statistics. Thus, methods that use published survival curves and summary statistics to reproduce statistics for economic evaluations are essential. Four methods have been identified: two traditional methods 1) least squares method, 2) graphical method; and two recently proposed methods by 3) Hoyle and Henley, 4) Guyot et al. The four methods were first individually reviewed and subsequently assessed regarding their abilities to estimate mean survival through a simulation study. Methods A number of different scenarios were developed that comprised combinations of various sample sizes, censoring rates and parametric survival distributions. One thousand simulated survival datasets were generated for each scenario, and all methods were applied to actual IPD. The uncertainty in the estimate of mean survival time was also captured. Results All methods provided accurate estimates of the mean survival time when the sample size was 500 and a Weibull distribution was used. When the sample size was 100 and the Weibull distribution was used, the Guyot et al. method was almost as accurate as the Hoyle and Henley method; however, more biases were identified in the traditional methods. When a lognormal distribution was used, the Guyot et al. method generated noticeably less bias and a more accurate uncertainty compared with the Hoyle and Henley method. Conclusions The traditional methods should not be preferred because of their remarkable overestimation. When the Weibull distribution was used for a fitted model, the Guyot et al. method was almost as accurate as the Hoyle and Henley method. However, if the lognormal distribution was used, the Guyot et al. method was less biased compared with the Hoyle and Henley method. PMID:25803659

  18. A Model for Creating Engaged Land-Grant Universities: Penn State's Engagement Ladder Model

    ERIC Educational Resources Information Center

    Aronson, Keith R.; Webster, Nicole

    2007-01-01

    The original mission of the state and land-grant university was to engage with communities to solve problems and improve the quality of life for the citizenry. Today most state and land-grant universities have moved far away from their original mission and are struggling to become engaged with the communities they serve. In this case study, we…

  19. The Penn State ORSER system for processing and analyzing ERTS and other MSS data

    NASA Technical Reports Server (NTRS)

    Mcmurtry, G. J.; Petersen, G. W. (Principal Investigator); Borden, F. Y.; Weeden, H. A.

    1974-01-01

    The author has identified the following significant results. The office for Remote Sensing of Earth Resources (ORSER) of the Space Science and Engineering Laboratory at the Pennsylvania State University has developed an extensive operational system for processing and analyzing ERTS-1 and similar multispectral data. The ORSER system was developed for use by a wide variety of researchers working in remote sensing. Both photointerpretive techniques and automatic computer processing methods have been developed and used, separately and in a combined approach. A remote Job Entry system permits use of an IBM 370/168 computer from any compatible remote terminal, including equipment tied in by long distance telephone connections. An elementary cost analysis has been prepared for the processing of ERTS data.

  20. The PennBMBI: Design of a General Purpose Wireless Brain-Machine-Brain Interface System.

    PubMed

    Liu, Xilin; Zhang, Milin; Subei, Basheer; Richardson, Andrew G; Lucas, Timothy H; Van der Spiegel, Jan

    2015-04-01

    In this paper, a general purpose wireless Brain-Machine-Brain Interface (BMBI) system is presented. The system integrates four battery-powered wireless devices for the implementation of a closed-loop sensorimotor neural interface, including a neural signal analyzer, a neural stimulator, a body-area sensor node and a graphic user interface implemented on the PC end. The neural signal analyzer features a four channel analog front-end with configurable bandpass filter, gain stage, digitization resolution, and sampling rate. The target frequency band is configurable from EEG to single unit activity. A noise floor of 4.69 μVrms is achieved over a bandwidth from 0.05 Hz to 6 kHz. Digital filtering, neural feature extraction, spike detection, sensing-stimulating modulation, and compressed sensing measurement are realized in a central processing unit integrated in the analyzer. A flash memory card is also integrated in the analyzer. A 2-channel neural stimulator with a compliance voltage up to ± 12 V is included. The stimulator is capable of delivering unipolar or bipolar, charge-balanced current pulses with programmable pulse shape, amplitude, width, pulse train frequency and latency. A multi-functional sensor node, including an accelerometer, a temperature sensor, a flexiforce sensor and a general sensor extension port has been designed. A computer interface is designed to monitor, control and configure all aforementioned devices via a wireless link, according to a custom designed communication protocol. Wireless closed-loop operation between the sensory devices, neural stimulator, and neural signal analyzer can be configured. The proposed system was designed to link two sites in the brain, bridging the brain and external hardware, as well as creating new sensory and motor pathways for clinical practice. Bench test and in vivo experiments are performed to verify the functions and performances of the system. PMID:25769171

  1. PENN Working Papers in Educational Linguistics. Volume 7, Number 2/Fall 1991.

    ERIC Educational Resources Information Center

    DeLorme, R. Stuart; And Others

    1991-01-01

    This issue presents works in progress by students and professors at the University of Pennsylvania. Papers are generally based on research conducted for courses offered in the Language in Education Division of the Graduate School of Education. This issue contains the following papers: "Do Second Language Learners Need Negotiation?" (Teresa Pica);…

  2. Creating a Community of Teachers: The Penn State Course in College Teaching.

    ERIC Educational Resources Information Center

    Enerson, Diane M.; And Others

    In the early 1990s, Pennsylvania State University's IDP (Instructional Development Program) Center for Excellence in Learning and Teaching provided separate programs for training teaching assistants (TAs) and faculty development. Neither program appeared to meet the needs of its intended audience. In the fll of 1992, the Center began offering the…

  3. Changing Perceptions of the University as a Community of Learning: The Case of Penn State

    ERIC Educational Resources Information Center

    Willits, Fern K.; Brennan, Mark A.

    2016-01-01

    Writing in 1990 for the Carnegie Foundation and the American Council on Education, Ernest Boyer described the importance of strengthening the colleges and universities as vital communities of learning by emphasizing six critical dimensions or characteristics of campus life: educationally purposeful, open, just, disciplined, caring, and…

  4. The Penn State ORSER system for processing and analyzing ERTS data

    NASA Technical Reports Server (NTRS)

    Mcmurtry, G. J.; Borden, F. Y.; Weeden, H. A.; Petersen, G. W.

    1974-01-01

    The Office for Remote Sensing of Earth Resources (ORSER) of the Space Science and Engineering Laboratory (SSEL) at The Pennsylvania State University has developed an extensive operational system for processing and analyzing ERTS-1 and similar multispectral data. Specific results obtained by using this system include a study of land use, discrimination between types of forest resources and vegetation, detection of previously unknown geologic faults and correlation of these with known mineral deposits and ground water, mapping of mine spoils in the anthracite region of eastern Pennsylvania, mapping of strip mines and acid mine drainage in Central Pennsylvania, agricultural land use mapping, and detection of gypsy moth infestation.

  5. Penn State Activities in the NASA GSFC Transmissive Microshutter Array Technology Development Program

    NASA Technical Reports Server (NTRS)

    Ge, Jian

    2002-01-01

    This is a one year contract starting on April 1, 2001 to design the Rapid Infrared and Visible Multiple Object Spectrometer (RIVMOS) and its auxiliary dispersing elements, design and fabricate silicon grisms, and reduce testing data with silicon grisms. Here I report our progress made during the funding period.

  6. A Vice-President from the Business World Brings a New Bottom Line to Penn.

    ERIC Educational Resources Information Center

    van der Werf, Martin

    1999-01-01

    The executive vice-president of the University of Pennsylvania is credited with making significant changes in both the administration and the campus, using cost-cutting and change strategies from his business experience. Outsourcing, training for employees who might be terminated, substantial savings and new revenue, and gentrification of…

  7. A brief history of graduate distance education in nuclear engineering at Penn State Univ

    SciTech Connect

    Hochreiter, L. E.; Zimmerman, D. L.; Brenizer Jr, J. S.; Stark, M. A.

    2006-07-01

    The Pennsylvania State University Nuclear Engineering Distance Education Program has a twenty year history of providing graduate level distance education in Nuclear Engineering. The Distance Education Program was initiated as a specific program which was developed for the Westinghouse Energy Systems Divisions in Pittsburgh. In 1983, Carnegie-Mellon University (CMU) decided to terminate its small Nuclear Engineering Program. Up until that time, Westinghouse employees could enroll at CMU for graduate classes in Nuclear Engineering as well as other engineering disciplines and could obtain a masters degree or if desired, could continue for a Ph.D. degree. (authors)

  8. Penn State axial flow turbine facility: Performance and nozzle flow field

    NASA Technical Reports Server (NTRS)

    Lakshminarayana, B.; Zaccaria, M.; Itoh, S.

    1991-01-01

    The objective is to gain a thorough understanding of the flow field in a turbine stage including three-dimensional inviscid and viscid effects, unsteady flow field, rotor-stator interaction effects, unsteady blade pressures, shear stress, and velocity field in rotor passages. The performance of the turbine facility at the design condition is measured and compared with the design distribution. The data on the nozzle vane static pressure and wake characteristics are presented and interpreted. The wakes are found to be highly three-dimensional, with substantial radial inward velocity at most spanwise locations.

  9. 75 FR 81331 - Surety Companies Acceptable on Federal Bonds: Termination-Penn Millers Insurance Company

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-27

    ..., at 75 FR 38192. FOR FURTHER INFORMATION CONTACT: Surety Bond Branch at (202) 874-6850. SUPPLEMENTARY... of the Treasury, Financial Management Service, Financial Accounting and Services Division, Surety.... Laura Carrico, Director, Financial Accounting and Services Division, Financial Management...

  10. Mentoring in the Philadelphia GO-GIRL Program: Impact on Penn's Graduate School of Education Student Mentors

    ERIC Educational Resources Information Center

    Slaughter-Defoe, Diana; English-Clarke, Traci

    2010-01-01

    The role of mentor development in implementing an out-of-school math and science Saturday program for middle-school girls is examined, using content analyses performed on journal entries that four college and graduate school-level mentors completed during the second year of the pilot program. Findings suggest that mentors matured and changed from…

  11. 76 FR 24472 - UGI Central Penn Gas, Inc.; Notice of Petition for Rate Approval Take notice that on April 8...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-02

    ... Large Volume Daily Delivery Service rate contained in Rate Schedule L on file with the Pennsylvania...)(1)(ii) of the Commission's regulations a rate election for interruptible transportation service. CPG... subscribed docket(s). For assistance with any FERC Online service, please e-mail...

  12. Development of microsatellite markers for Manilkara maxima T.D. Penn. (Sapotaceae) and their use in conservation genetics.

    PubMed

    Silva-Junior, José Audenor; de Souza França, Daniele; Moraes, Ramiris César Souza; Gaiotto, Fernanda Amato

    2016-06-01

    Manilkara maxima is an endemic tree species of the Atlantic Forest in southern Bahia, Brazil. It is considered important for forest conservation due to its mutualistic interactions with endemic and endangered animals. Our aim was to develop microsatellite markers to estimate genetic diversity in order to provide information for effectiveness of future conservation programs. We used next generation sequencing technology to develop the first specific microsatellite markers for M. maxima. Seventeen new microsatellite loci were applied in 72 individuals sampled in three natural populations. On average, the number of alleles per loci was 8.8. The expected heterozygosity varied between 0.72 and 0.77, indicating that the developed set of molecular markers is useful for genetic diversity studies. Additionally, the estimated value for the combined probability of exclusion (Q) was greater than 0.999, which indicates the powerful of these molecular tools for paternity and kinship analysis. Our results demonstrate that the set of microsatellites developed in this work is a powerful tool for population genetics, molecular ecology and conservation biology purposes. PMID:27061192

  13. Precision Radial Velocities in the near-infrared Y and H bands with the Penn State Pathfinder Instrument

    NASA Astrophysics Data System (ADS)

    Mahadevan, Suvrath; Ramsey, L.; Redman, S.; Bender, C.; Botzer, B.; Terrien, R.; Osterman, S.; Diddams, S.; Ycas, G.; Quinlan, F.; Roy, A.; Zonak, S.

    2011-01-01

    Precision radial velocities in the near infrared can help detect terrestrial mass planets around mid and late M dwarfs that are typically too faint in the optical for effective monitoring. We have demonstrated 10-15 m/s radial velocity precision in the NIR Y band with our warm-bench fiber-fed Pathfinder instrument at the 9m Hobby Eberly telescope, and will present these results as well as discuss results from the first on-sky observations with an H band laser frequency comb. We will also present the instrumental upgrades and modification to Pathfinder that have made high NIR velocity precision possible with the use of new calibration sources like Uranium lamps and laser combs. The ability to achieve this level of precision with a test bed bodes well for a stabilized spectrograph built on these principles, and we discuss progress toward this as well as challenges like modal noise and telluric absorption correction.

  14. Vadose zone transport of natural and synthetic estrogen hormones at Penn State's "Living Filter" wastewater irrigation site

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The increase in endocrine disrupting compounds (EDCs) in the environment has generated new research focused on the behavior of these compounds in natural soil and water ecosystems. To understand how estrogens behave in the soil environment as a result of 25+ years of wastewater irrigation, soils fro...

  15. Humanities mini-course curricula for midcareer health professionals at the Penn State Milton S. Hershey Medical Center.

    PubMed

    Myers, Kimberly R; George, Daniel R

    2012-08-01

    The field of medical humanities has traditionally focused on medical students and, more recently, on premedical undergraduates. Comparatively little formal humanities pedagogy has been dedicated to midcareer health professionals. To address this lack, the Department of Humanities at the Pennsylvania State University College of Medicine and the Milton S. Hershey Medical Center designed eight annual humanities mini-courses for faculty and staff throughout the college and medical center.These mini-courses fell into four categories: reading, reflection, and discussion; creative expression; technology; and ethics. They were geared toward midcareer health professionals who were seeking new intellectual and creative stimulation and variety in daily routine. They also provided humanities faculty the opportunity to devote attention to topics that capitalize on their professional training and that interest them personally.Participants indicated a high degree of satisfaction with the mini-courses for four principal reasons: (1) learning the tools and methodologies of a new discipline or domain other than biomedicine, (2) using their minds and training in uncustomary ways, (3) forming new alliances with colleagues (which served to lessen the sense of professional isolation), and (4) enjoying a respite from the stressful flow of the workday. Humanities faculty facilitators provided more mixed responses but agreed that conducting the mini-courses had been a positive overall experience.Although this article provides a foundational framework for the development of a humanities mini-course series, the authors encourage others to replicate these curricula in other medical settings as an important step toward a robust pedagogy designed for midcareer health care professionals. PMID:22827992

  16. The Penn State Safety Floor: Part II--Reduction of fall-related peak impact forces on the femur.

    PubMed

    Casalena, J A; Badre-Alam, A; Ovaert, T C; Cavanagh, P R; Streit, D A

    1998-08-01

    The goal of this study was to develop and validate a finite element model (FEM) for use in the design of a flooring system that would provide a stable walking surface during normal locomotion but would also deform elastically under higher loads, such as those resulting from falls. The new flooring system is designed to reduce the peak force on the femoral neck during a lateral fall onto the hip. The new flooring system is passive in nature and exhibits two distinct stiffnesses. During normal activities, the floor remains essentially rigid. Upon impact, the floor collapses and becomes significantly softer. The flooring system consists of a multitude of columns supporting a continuous walking surface. The columns were designed to remain stiff up to a specific load and, after exceeding this load, to deform elastically. The flooring returns to its original shape after impact. Part I of this study presented finite element and experimental results demonstrating that the floor deflection during normal walking remained less than 2 mm. To facilitate the floor's development further, a nonlinear finite element model simulating the transient-impact response of a human hip against various floor configurations was developed. Nonlinearities included in the finite element models were: changing topology of deformable-body-to-deformable-body contact, snap-through buckling, soft tissue stiffness and damping, and large deformations. Experimental models developed for validating the finite element model included an anthropomorphic hip, an impact delivery mechanism, a data collection system, and four hand-fabricated floor tiles. The finite element model discussed in this study is shown to capture experimentally observed trends in peak femoral neck force reduction as a function of flooring design parameters. This study also indicates that a floor can be designed that deflects minimally during walking and reduces the peak force on the femoral neck during a fall-related impact by 15.2 percent. PMID:10412424

  17. SO{sub 2} and NO{sub x} control technologies - developments at Penn State`s Combustion Laboratory

    SciTech Connect

    Pisupati, S.V.

    1996-12-31

    The majority of pollution from coal combustion is from the emission of sulfur and nitrogen oxides. The Clean Air Act Amendments of 1990 established the Acid Rain Program under Title IV to achieve significant environmental and public health benefits through reductions in electric utility emissions of SO{sub 2} and NO{sub x}. The Act calls for significant reduction in NO{sub x} emissions by year 2000. The data obtained by EPA showed that 1995 SO{sub 2} emissions declined sharply by approximately 5 million tons below 1980 levels at the 445 Phase I affected electric utilities. The data also indicated that the boilers involved in the first stage of the NO{sub x} reduction program met Phase I emission standards of 0.5 lbs/MMBtu for dry bottom, wall fired units, and 0.45 lbs/MMBtu for tangentially fired boilers. Fluidized bed combustors, due to inherently low operating temperatures, produce less thermal NO{sub x} than pulverized coal units. However, with Ozone Transport Commission`s deliberations, it is expected that NO{sub x} emission limits could be lowered even further up to 0.15 lb/MMBtu for the fluidized bed combustion Units. Therefore, NO{sub x} reduction is important not only from an acid rain point of view but also from ozone formation at lower altitudes.

  18. A resolution congratulating the Penn State University wrestling team for winning the 2014 National Collegiate Athletic Association Wrestling Championships.

    THOMAS, 113th Congress

    Sen. Casey, Robert P., Jr. [D-PA

    2014-04-02

    04/02/2014 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S2134; text as passed Senate: CR S2096-2097) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  19. 75 FR 38127 - Visteon Systems, LLC North Penn Plant Electronics Products Group Including On-Site Leased Workers...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-01

    ..., 2009 (74 FR 2136). The certification was amended on December 29, 2008 to correct the impact date to read December 6, 2008. The notice was published in the Federal Register on January 6, 2009 (74 FR 469... Including On-Site Leased Workers From Ryder Integrated Logistics and Including On-Site Workers From...

  20. Bringing atmospheric sciences to middle/high school students and teachers through the Penn State Weather Camp

    NASA Astrophysics Data System (ADS)

    Jenkins, G. S.; Syrett, W.; Knight, P.

    2002-05-01

    A one-week resident camp during the summer has been developed that provides students and teachers with hands-on instruction and classroom lessons. Students entering 8th through 10th grades are selected for the camp and special efforts are made in having traditionally underrepresented groups participate in the Weather Camp. The contents of the camp include: balloon launches, contouring exercises, simple forecasting techniques, understanding past and future climatic conditions, a climate change debate, tours of private and government weather organizations. One special highlight of the camp is the making of a weather forecast in the TV studio that is taped and given to the weather camper. The weather camp for teachers is being launched in the summer of 2002 with the goal of hosting 15-24 teachers. Teachers can receive two credits during the weather camp assuming that 60 hours of in-class and out of class work is completed. Efforts and strategies are being made to bring teachers from rural and urban settings in order to take their experiences back to their classrooms. Highlights of the first year of the weather camp are presented along with second year and future efforts.

  1. Development of a Comprehensive Recruitment Program Targeted at the Penn State Student Market. AIR Forum 1979 Paper.

    ERIC Educational Resources Information Center

    Spiro, Louis M.; McCallus, Joseph L.

    A time sequence of recruitment activities was developed using high school data to represent the total, potential, and actual student markets for Pennsylvania State University. High schools with similar characteristics were grouped according to potential recruitment yields. Under the assumption that college decision-making behavior approximated the…

  2. Does the Penn State Reticence Program Work?: A Comparison of Special and Regular Options of a Basic Speech Communication Course.

    ERIC Educational Resources Information Center

    Kelly, Lynne; Keaten, James

    A study assessed the effectiveness of the Pennsylvania State University (PSU) Reticence Program as a treatment for individuals with communication difficulties, such as communication apprehension, reticence, and shyness. Several standardized tests of social communication problems were used in a pretest-posttest design with a control group and two…

  3. Sea-Level Static Testing of the Penn State Two-Dimensional Rocket-Based Combined Cycle (RBCC) Testbed

    NASA Technical Reports Server (NTRS)

    Cramer, J. M.; Pal, S.; Marshall, W. M.; Santoro, R. J.

    2003-01-01

    The present results indicated that: 1.Significant RBCC ejector mode database has been generated for single and twin thruster configuration and for global and local measurements. 2. Ongoing analysis and correlation effort for MSFC CFD modeling and turbulent shear layer analysis was completed. 3. The potential follow-on activities are: detailed measurements of air flow static pressure and velocity profiles; investigation other thruster spacing configurations; performing fundamental shear layer mixing study; and demonstrating single-shot Raman measurements.

  4. Proceedings of the Annual Penn State Microcomputer Information Exchange Conference (2nd, University Park, Pennsylvania, March 11-12, 1983).

    ERIC Educational Resources Information Center

    Streibel, Michael J., Comp.

    This collection of 17 conference presentations includes (1) "Project LOGO: A Study in Cognitive Enhancement Using Microcomputers," Henry Dobson; (2) "Tender Loving Care for Your Terrific Little Computer (TLC for your TLC)," Carol Dwyer and Karl Kelly; (3) "Teaching Micro-Literacy to Kids," Robert Gillingham; (5) "Teaching Music with the Apple II…

  5. The Penn State - Toruń Centre for Astronomy Planet Search stars (Corrigendum). III. The sample of evolved stars

    NASA Astrophysics Data System (ADS)

    Niedzielski, A.; Deka-Szymankiewicz, B.; Adamczyk, M.; Adamów, M.; Nowak, G.; Wolszczan, A.

    2016-05-01

    Based on observations obtained with the Hobby-Eberly Telescope, which is a joint project of the University of Texas at Austin, the Pennsylvania State University, Stanford University, Ludwig-Maximilians-Universität München, and Georg-August-Universität Göttingen.

  6. Proceedings of the 23rd Annual Penn Linguistics Colloquium. University of Pennsylvania Working Papers in Linguistics, Volume 6, Number 1.

    ERIC Educational Resources Information Center

    Alexander, Jim, Ed.; Han, Na-Rae, Ed.; Fox, Michelle Minnick, Ed.

    This issue includes the following articles: "Assimilation to the Unmarked" (Eric Bakovic); "On the Non-Universality of Functional Projections and the Effects on Parametrized Variation: Evidence from Creoles" (Marlyse Baptista); "What Turkish Acquisition Tells Us about Underlying Word Order and Scrambling" (Natalie Batman-Ratyosyan, Karin…

  7. The Center for Environmental Kinetics Analysis: an NSF- and DOE-funded Environmental Molecular Science Institute (EMSI) at Penn State

    SciTech Connect

    S. L. Brantley; William D. Burgos; Brian A. Dempsey; Peter J. Heaney; James D. Kubicki; Peter C. Lichtner; Bruce E. Logan; Carmen E. Martinez; Karl T. Mueller; Kwadwo A. Osseo-Asare; Ming Tien; Carl I. Steefel, Glenn A. Waychunas; and John M. Zachara

    2007-04-19

    Physicochemical and microbiological processes taking place at environmental interfaces influence natural processes as well as the transport and fate of environmental contaminants, the remediation of toxic chemicals, and the sequestration of anthropogenic CO2. A team of scientists and engineers has been assembled to develop and apply new experimental and computational techniques to expand our knowledge of environmental kinetics. We are also training a cohort of talented and diverse students to work on these complex problems at multiple length scales and to compile and synthesize the kinetic data. Development of the human resources capable of translating molecular-scale information into parameters that are applicable in real world, field-scale problems of environmental kinetics is a major and relatively unique objective of the Institute's efforts. The EMSI team is a partnership among 10 faculty at The Pennsylvania State University (funded by the National Science Foundation Divisions of Chemistry and Earth Sciences), one faculty member at Juniata College, one faculty member at the University of Florida, and four researchers drawn from Los Alamos National Laboratory, Pacific Northwest National Laboratory, and Lawrence Berkeley National Laboratory (funded by the Department of Energy Division of Environmental Remediation Sciences). Interactions among the applied and academic scientists drives research approaches aimed toward solving important problems of national interest. The Institute is organized into three interest groups (IGs) focusing on the processes of dissolution (DIG), precipitation (PIG), and microbial reactions at surfaces (BIG). Some of the research activity from each IG is highlighted to the right. The IGs interact with each other as each interest group studies reactions across the molecular, microscopic, mesoscopic and, in most cases, field scales. For example, abiotic dissolution and precipitation reactions of Fe oxides as studied in the Dissolution IG provides the baseline for kinetic behavior as the BIG researches the interaction of microorganisms with these same minerals. The attachment of bacteria and redox chemistry that occurs between microorganisms and minerals are critical factors in maintaining groundwater quality and remediation of many toxic waste sites and is one of the main thrusts of research within our EMSI. The IGs also participate in using visualization tools to promote greater understanding of complex environmental data. As a whole, CEKA is also working to compile environmental kinetics data into a cyberinfrastructure and database. The database can be accessed at: http://keystone.ist.psu.edu/.

  8. Proceedings of the Annual Penn Linguistics Colloquium (21st, Philadelphia, Pennsylvania, February 22-23, 1997). University of Pennsylvania Working Papers in Linguistics, Volume 4, Number 2.

    ERIC Educational Resources Information Center

    Dimitriadis, Alexis, Ed.; Siegel, Laura, Ed.; Surek-Clark, Clarissa, Ed.; Williams, Alexander, Ed.

    This issue contains the following articles: "The Pragmatics of Wh-Question Intonation in English" (Christine Bartels); "The Nature of Object Agreement in Hungarian" (Huba Bartos); "Voah Mei Daett Sei Deitsh: Developments in the Vowel System of Pennsylvania German" (David Bowie); "Event Time Properties" (Gerhard Brugger); "Polarity in Spanish,…

  9. Microseismic monitoring of CO2 injection at the Penn West Enhanced Oil Recovery pilot project, Canada: implications for detection of wellbore leakage.

    PubMed

    Martínez-Garzón, Patricia; Bohnhoff, Marco; Kwiatek, Grzegorz; Zambrano-Narváez, Gonzalo; Chalaturnyk, Rick

    2013-01-01

    A passive seismic monitoring campaign was carried out in the frame of a CO2-Enhanced Oil Recovery (EOR) pilot project in Alberta, Canada. Our analysis focuses on a two-week period during which prominent downhole pressure fluctuations in the reservoir were accompanied by a leakage of CO2 and CH4 along the monitoring well equipped with an array of short-period borehole geophones. We applied state of the art seismological processing schemes to the continuous seismic waveform recordings. During the analyzed time period we did not find evidence of induced micro-seismicity associated with CO2 injection. Instead, we identified signals related to the leakage of CO2 and CH4, in that seven out of the eight geophones show a clearly elevated noise level framing the onset time of leakage along the monitoring well. Our results confirm that micro-seismic monitoring of reservoir treatment can contribute towards improved reservoir monitoring and leakage detection. PMID:24002229

  10. Microseismic Monitoring of CO2 Injection at the Penn West Enhanced Oil Recovery Pilot Project, Canada: Implications for Detection of Wellbore Leakage

    PubMed Central

    Martínez-Garzón, Patricia; Bohnhoff, Marco; Kwiatek, Grzegorz; Zambrano-Narváez, Gonzalo; Chalaturnyk, Rick

    2013-01-01

    A passive seismic monitoring campaign was carried out in the frame of a CO2-Enhanced Oil Recovery (EOR) pilot project in Alberta, Canada. Our analysis focuses on a two-week period during which prominent downhole pressure fluctuations in the reservoir were accompanied by a leakage of CO2 and CH4 along the monitoring well equipped with an array of short-period borehole geophones. We applied state of the art seismological processing schemes to the continuous seismic waveform recordings. During the analyzed time period we did not find evidence of induced micro-seismicity associated with CO2 injection. Instead, we identified signals related to the leakage of CO2 and CH4, in that seven out of the eight geophones show a clearly elevated noise level framing the onset time of leakage along the monitoring well. Our results confirm that micro-seismic monitoring of reservoir treatment can contribute towards improved reservoir monitoring and leakage detection. PMID:24002229

  11. Family Literacy: A Research Agenda to Build the Future. Report from Penn State's Goodling Institute for Research in Family Literacy Think Tank.

    ERIC Educational Resources Information Center

    Askov, Eunice N.

    A think tank on researching family literacy was held to brainstorm a national research agenda for family literacy. The think tank brought together 12 researchers, policymakers, and practitioners involved in family literacy. Key themes emerging during the think tank were as follows: (1) family literacy is difficult to research because it is…

  12. Public Health Potential of Farmers’ Markets on Medical Center Campuses: A Case Study From Penn State Milton S. Hershey Medical Center

    PubMed Central

    Kraschnewski, Jennifer L.; Rovniak, Liza S.

    2011-01-01

    There are currently 7175 farmers’ markets in the United States, and these organizations are increasingly viewed as one facet of the solution to national health problems. There has been a recent trend toward establishing markets on medical center campuses, and such partnerships can augment a medical center's ability to serve community health. However, to our knowledge no studies have described the emergence of a market at a medical center, the barriers and challenges such an initiative has faced, or the nature of programming it may foster. We provide a qualitative description of the process of starting a seasonal, once-a-week, producers-only market at the Pennsylvania State Hershey Medical Center, and we call for greater public health attention to these emerging community spaces. PMID:22021298

  13. A resolution congratulating the Penn State University women's volleyball team for winning the 2013 National Collegiate Athletic Association Women's Volleyball Championship.

    THOMAS, 113th Congress

    Sen. Toomey, Pat [R-PA

    2014-02-04

    02/04/2014 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S773-774; text as passed Senate: CR S767-768) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  14. Communicator, 1997.

    ERIC Educational Resources Information Center

    Bortolussi, Vicki, Ed.

    1997-01-01

    The CAG "Communicator" focus is on serving gifted students in California. This document consists of the four issues of "communicator" issued during 1997. Featured articles include: (1) "The Gifted Student At Risk. It Can't Be True" (Judy Roseberry); (2) "Tech Net-Technology and At-Risk Students" (Judy Lieb); (3) "Reviving Ophelia: Saving the…

  15. 75 FR 14659 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-26

    ... Bureau of the Public Debt Proposed Collection: Comment Request ACTION: Notice and request for comments... of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A)). Currently the Bureau of the Public Debt within... Debt, Judi Owens, 200 Third Street, A4-A, Parkersburg, WV 26106-1328, or judi.owens@bpd.treas.gov ....

  16. Searching for the Developmental Stages of the Visionary Leader: Examination of Complex Cumulative Life Stories.

    ERIC Educational Resources Information Center

    Schuttloffel, Merylann Mimi J.

    This paper explores whether potential school leaders can be identified and encouraged earlier in their lives. The story of Judy, a teacher who became the leader of an innovative technology project, provides clues to her development as a professional and her creation of the vision that inspired the project. The numerous markers in Judy's life that…

  17. The Employment Context. The Impact of the Law on the Lives of Women. Gender and American Law Series, No. 3.

    ERIC Educational Resources Information Center

    Maschke, Karen J., Ed.

    This book contains the following 14 articles on the effects of law on women in the United States: "Protection of Women Workers and the Courts: A Legal Case History" (Ann Corinne Hill); "Sexual Harassment and Race: A Legal Analysis of Discrimination" (Judy Trent Ellis); "Comparable Worth: Is This a Theory for Black Workers?" (Judy Scales-Trent);…

  18. NIH Research Leads to Cervical Cancer Vaccine

    MedlinePlus

    ... Issues Sexually Transmitted Diseases NIH Research Leads to Cervical Cancer Vaccine Past Issues / Fall 2008 Table of Contents ... in women, the cause of the majority of cervical cancers. Photo courtesy of Judy Folkenberg, NLM Writer By ...

  19. Exercise

    MedlinePlus

    ... article Exercise / physical activity with MS Judy Boone, physical therapist Lynn Williams, Dan Melfi and Dave Altman discuss ... adjusted as changes occur in MS symptoms. A physical therapist experienced with MS can be helpful in designing, ...

  20. Current Perspectives on Pronunciation. Practices Anchored in Theory.

    ERIC Educational Resources Information Center

    Morley, Joan, Ed.

    A collection of essays on pronunciation instruction theory and practice includes: "Teaching Pronunciation as Communication" (Marianne Celce-Murcia); "Learner Variables and Prepronunciation Considerations in Teaching Pronunciation" (Rita Wong); "Pronunciation and Listening Comprehension" (Judy B. Gilbert); "Pronunciation Tutorials for Nonnative…

  1. Creativity: The Human Resource.

    ERIC Educational Resources Information Center

    Lewis, Richard W.

    1979-01-01

    The author discusses an exhibition entitled "Creativity--The Human Resource." The exhibition examines the work of 15 Americans, such as designer Buckminster Fuller and artist Judy Chicago, who have contributed in special ways to the arts and sciences. (PHR)

  2. S.Res.344 — 113th Congress (2013-2014) A resolution congratulating the Penn State University women's volleyball team for winning the 2013 National Collegiate Athletic Association Women's Volleyball Championship.

    THOMAS, 113th Congress

    Sen. Toomey, Pat [R-PA

    2014-02-04

    02/04/2014 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S773-774; text as passed Senate: CR S767-768) (All Actions)

  3. S.Res.379 — 113th Congress (2013-2014) A resolution congratulating the Pennsylvania State University IFC/Panhellenic Dance Marathon ("THON") on its continued success in support of the Four Diamonds Fund at Penn State Hershey Children's...

    THOMAS, 113th Congress

    Sen. Casey, Robert P., Jr. [D-PA

    2014-03-11

    03/11/2014 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S1527-1528; text as passed Senate: CR S1521-1522) (All Actions)

  4. Assessing the Usefulness of AIRS Radiance Observations in a 4D-Var Assimilation Scheme Using the Penn State/NCAR Mesoscale Model Version 5 (MM5) and a Stand Alone Radiative Transfer Algorithm (SARTA)

    NASA Technical Reports Server (NTRS)

    Carrier, M.; Zou, X.; Lapenta, W. M.; Jedlovec, G.

    2004-01-01

    Short-term precipitation forecast skill remains poor despite further advances in numerical modeling and data analysis. Utilizing indirect observations, such as the radiance observations obtained from the Atmospheric Infrared Sounder (AIRS), in a 4D-Var assimilation scheme may lead to a rapid improvement in the skill of 12-h QPF. In order to investigate the usefulness of AIRS observations, the adjoint code of a radiative transfer model (SARTA) is developed and linked to MM5 4D-Var system. A statistical comparison of the AIRS radiances with those calculated using the linked MMS-SARTA model is carried out to assess errors in the radiative transfer model, MM5 and AIRS data, and to develop a quality control scheme. Outliers and any bias that may exist in radiative transfer model, MM5 and AIRS data are identified. An adjoint sensitivity study, utilizing the SARTA adjoint model, is then done to identify the relative sensitivities of each spectral channel to such parameters as atmospheric temperature, pressure, and mixing ratio. Another sensitivity study is done using the MM5 alone to determine the sensitivity of the 12-h QPF to model parameters such as atmospheric temperature, pressure, and mixing ratio under various weather regimes (i.e. summertime convection, winter snowfall). Results from these two types of adjoint sensitivity studies are used to determine which AIRS channels contribute most to 12-h QPF under differing weather regimes. This information is useful when conducting 4D-Var experiments using a subset of the 2378 AIRS spectral channels. Finally, 4D-Var experiments are done to analyze the impact of the AIRS observations on the quality of the 12-h QPF results. This project falls under the data assimilation general session topic as specified by the conference organizers.

  5. Generalizing the OpenURL Framework beyond References to Scholarly Works: The Bison-Fute Model; Digital Libraries and Education: Trends and Opportunities; E-Books and Their Future in Academic Libraries: An Overview; Penn State Visual Image User Study.

    ERIC Educational Resources Information Center

    Van de Sompel, Herbert; Beit-Arie, Oren; Roes, Hans; Snowhill, Lucia; Pisciotta, Henry; Brisson, Roger; Ferrin, Eric; Dooris, Michael; Spink, Amanda

    2001-01-01

    Includes four articles that discuss a conceptual framework for open and context-sensitive reference linking for Web-based scholarly information; issues for academic libraries due to increased use of information and communication technologies; the future of electronic books in academic libraries; and an academic library user study on the needs for…

  6. Modelling the impact of blood flow on the temperature distribution in the human eye and the orbit: fixed heat transfer coefficients versus the Pennes bioheat model versus discrete blood vessels

    NASA Astrophysics Data System (ADS)

    Flyckt, V. M. M.; Raaymakers, B. W.; Lagendijk, J. J. W.

    2006-10-01

    Prediction of the temperature distribution in the eye depends on how the impact of the blood flow is taken into account. Three methods will be compared: a simplified eye anatomy that applies a single heat transfer coefficient to describe all heat transport mechanisms between the sclera and the body core, a detailed eye anatomy in which the blood flow is accounted for either by the bioheat approach, or by including the discrete vasculature in the eye and the orbit. The comparison is done both for rabbit and human anatomies, normo-thermally and when exposed to homogeneous power densities. The first simplified model predicts much higher temperatures than the latter two. It was shown that the eye is very hard to heat when taking physiological perfusion correctly into account. It was concluded that the heat transfer coefficient describing the heat transport from the sclera to the body core reported in the literature for the first simplified model is too low. The bioheat approach is appropriate for a first-order approximation of the temperature distribution in the eye when exposed to a homogeneous power density, but the discrete vasculature down to 0.2 mm in diameter needs to be taken into account when the heterogeneity of the temperature distribution at a mm scale is of interest.

  7. A resolution congratulating the Pennsylvania State University IFC/Panhellenic Dance Marathon ("THON") on its continued success in support of the Four Diamonds Fund at Penn State Hershey Children's Hospital.

    THOMAS, 113th Congress

    Sen. Casey, Robert P., Jr. [D-PA

    2014-03-11

    03/11/2014 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (consideration: CR S1527-1528; text as passed Senate: CR S1521-1522) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  8. A resolution congratulating the Pennsylvania State University IFC/Panhellenic Dance Marathon on its continued success in support of the Four Diamonds Fund at Penn State Hershey Children's Hospital.

    THOMAS, 112th Congress

    Sen. Casey, Robert P., Jr. [D-PA

    2012-03-29

    03/29/2012 Referred to the Committee on the Judiciary. (text of measure as introduced: CR S2257) (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  9. A resolution congratulating the Pennsylvania State University IFC/Panhellenic Dance Marathon ("THON") on its continued success in support of the Four Diamonds Fund at Penn State Hershey Children's Hospital.

    THOMAS, 112th Congress

    Sen. Casey, Robert P., Jr. [D-PA

    2011-03-29

    03/30/2011 Resolution agreed to in Senate without amendment and with a preamble by Unanimous Consent. (text: CR S2000) (All Actions) Tracker: This bill has the status Passed SenateHere are the steps for Status of Legislation:

  10. A phase II study of 5-fluorouracil, leucovorin, adriamycin, and cisplatin (FLAP) for metastatic gastric and gastroesophageal junction adenocarcinoma. A Penn Cancer Clinical Trial Group and Roswell Park Cancer Institute Community Oncology Research Program Trial.

    PubMed

    Vaughn, D J; Meropol, N J; Holroyde, C; Mintzer, D; Nuamah, I; Armstead, B; Douglass, H O; Haller, D G

    1997-06-01

    A Phase II study was performed to evaluate the activity and toxicity of 5-fluorouracil, leucovorin, Adriamycin, and cisplatin combination chemotherapy (FLAP) in patients with previously untreated advanced gastric and gastroesophageal (GE) junction adenocarcinoma. Forty-two consecutive patients were enrolled to received FLAP in this multi-institutional trial. Response, toxicity, and survival data were noted. Fifteen of 42 (36%) patients demonstrated objective responses, with two complete responses (5%) and 13 partial responses (31%). The median time to disease progression was 17 weeks, and the overall survival duration was 30 weeks. Myelosuppression was significant, requiring dose modifications, but there were no treatment-related deaths. FLAP is an active regimen in the treatment of advanced gastric and GE junction adenocarcinoma. We are presently using this regimen in the neoadjuvant setting in patients with gastric and GE junction cancers. PMID:9167745

  11. No Sex Please, I'm a Stressed New Mom

    MedlinePlus

    ... other factors, said Leavitt, a doctoral student in human development and family studies at Penn State University. The ... journal Sex Roles . SOURCES: Chelom Leavitt, doctoral student, human development and family studies, Penn State University, University Park, ...

  12. 76 FR 14426 - Notice of Lodging of Consent Decree Under the Comprehensive Environmental Response, Compensation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-16

    ... United States' claims against eight parties at the Breslube Penn Superfund Site, located in Coraopolis... Breslube Penn Performing Trust, which is performing the remedy at the site pursuant to a Consent...

  13. The Pennsylvania State University

    ERIC Educational Resources Information Center

    Burlingame, Philip J.; Dowhower, Andrea L.

    2009-01-01

    Founded in 1855 as the Farmer's High School, the Pennsylvania State University (Penn State) began as a small college in Centre County providing agricultural education to young men from regional farm families. Penn State became a land-grant university in 1863 following passage of the Morrill Act. Today, Penn State enrolls more than 83,000 students…

  14. Advocacy meets the scientific method.

    PubMed

    Bradford, J; Hilber, J A

    2001-01-01

    ABSTRACT Dr. Judith Bradford is a social science researcher who has been a key figure in the evolution of lesbian health research. With Caitlin Ryan, Judy was instrumental in creating the National Lesbian Health Care Survey (NLHCS) in the mid-1980s. After assuming the Directorship of the Survey and Evaluation Research Lab (SERL) at the Virginia Commonwealth University (VCU), she became involved in the recent Institute of Medicine (IOM) Committee process, which resulted in increased attention to lesbian health at the national level. The IOM Committee recommendations have been instrumental in lobbying efforts by Judy and others for inclusion of LBGT issues in Healthy People 2010, the United States Public Health Service blueprint used by PHS agencies nationwide. Judy's current activities include helping to develop the Lesbian Health Research Institute and serving as the part-time Director of Lesbian Health Research at Fenway Community Health in Boston. PMID:24802821

  15. 77 FR 26522 - Inland Waterways Users Board

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-04

    ...In Accordance with 10(a)(2) of the Federal Advisory Committee Act (Pub. L. 92-463), announcement is made of the forthcoming meeting. Name of Committee: Inland Waterways Users Board (Board). Date: June 6, 2012. Location: The OMNI William Penn Hotel, 530 William Penn Place, Pittsburgh, PA 15219 at 412-281-7100 or 1-800-843-6664 or www.omnihotels.com/FindAHotel/PittsburghWilliamPenn.aspx. Time:......

  16. 76 FR 65193 - Ocean Transportation Intermediary License; Applicants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-20

    .... Officer: Andrea Bigi, President (Qualifying Individual), Application Type: Business Structure Change... Individual); Ronald S. Penn, President, Application Type: New OFF License. Earth Relocation Inc (NVO &...

  17. The Immersion Phenomenon: English-Speaking Canadians Come to Grips with the Country's Language Duality = l'enseignement immersif: le Canada anglais se dote d'un instrument efficace pour soutenir la gageure du biblinguisme.

    ERIC Educational Resources Information Center

    Stern, H. H., Ed.

    1984-01-01

    A special journal issue on French language immersion programs in Canada consists of these articles: "The Immersion Phenomenon" (H. H. Stern); "For My Kids, It's French without Tears" (Judy Gibson); "A 'First' for a Toronto High School" (Claire Mian); "The Teachers, Key to the Success Story" (Andre Obadia); "A Promising Experiment at Ottawa…

  18. Self-Directed and Incidental Learning. Symposium 26. [Concurrent Symposium Session at AHRD Annual Conference, 2000.

    ERIC Educational Resources Information Center

    2000

    This packet contains three papers on self-directed and incidental learning from a symposium on human resource development (HRD). The first paper, "Self-Directed Learning for Supervisory Development" (Judy O'Neil, Maria Lamattina), reports on a study that looks at what research says needs to be in place to engage workers in self-directed learning…

  19. Close to Home: Library-Based Family Literacy. An Instructional Video for Library-Based Family Literacy Programs. [Videotape.

    ERIC Educational Resources Information Center

    American Library Association Video/Library Video Network, Towson, MD.

    This videtape is a guide hosted by Judy Woodruff to starting and enhancing a library-based family literacy project. Librarians and literacy providers learn: how to do a needs assessment, how to build a team within the library; how to develop a community coalition; how business partners contribute to family literacy programs; and how to recruit…

  20. Puppets, Music, Movement, Drama, and Kids.

    ERIC Educational Resources Information Center

    Molloy, Shivaun

    Classroom activity ideas for Japanese English as a second language students include a Punch and Judy puppet show (script included); a Halloween puppet trick-or-treat game to learn vocabulary and an American custom; a mime game using verbs; hangman; games of prediction, chance, and sorting or grouping; a Japanese card game similar to "slap"; a…

  1. Strategies in Composition: Ideas That Work in the Classroom.

    ERIC Educational Resources Information Center

    Bordner, Marsha S., Ed.

    This collection of essays by college and high school faculty represents a variety of practical approaches that can be used in composition classes. The essays and their authors are as follows (1) "Undercover Preparation" (Judy Anderson); (2) "Paragraph Development from Visualization: 'a paragraph ain't nothing but a sandwich!'" (Frances Noel…

  2. Self-Help and Community Education. Courier No. 28.

    ERIC Educational Resources Information Center

    ASPBAE Courier, 1983

    1983-01-01

    This journal consists of eight articles dealing with self-help and community education. Included in the volume are the following articles: "An Uphill Struggle--Self-Help in Bangladesh," by S. Harrison and Judy Saul; "How Not to Help a Local Community: A Case from South India," by Nora Sammut and Maria Theresa; "The High Cost of Manipulating…

  3. Parents' Role in Teenage Health Problems: Allies or Adversaries?. Meeting Highlights and Background Briefing Report. Report of a Family Impact Seminar (Washington, D.C., September 21, 1990).

    ERIC Educational Resources Information Center

    Ooms, Theodora; Owen, Todd

    This report contains highlights from a seminar on the role of parents in helping adolescents with their health problems. Comments by these panelists is summarized: Judy Areen, dean, Georgetown University Law Center; Barbara Popper, founder and board member of Children in Hospitals, Inc. and resource specialist at the Federation for Children with…

  4. Developing CPD in Britain and the Wider Europe. Proceedings of the Annual Conference of the UACE CVE (York, England, September 1997).

    ERIC Educational Resources Information Center

    Universities Association for Continuing Education, Cambridge (England).

    This document contains 8 plenary papers and 15 workshop presentations from a conference on development continuing professional development (CPD) and continuing vocational education (CVE) in United Kingdom and Europe. The following papers are included: "How CPD Adds Value to Professional Personnel and Development Activity" (Judy Whittaker); "CVE…

  5. DETECTION OF K-RAS AND P53 MUTATIONS IN SPUTUM SAMPLES OF LUNG CANCER PATIENTS USING LASER CAPTURE MICRODISSECTION MICROSCOPE AND MUTATION ANALYSIS

    EPA Science Inventory

    Detection of K-ras and p53 Mutations in Sputum Samples of Lung Cancer Patients Using Laser Capture Microdissection Microscope and Mutation Analysis

    Phouthone Keohavong a,*, Wei-Min Gao a, Kui-Cheng Zheng a, Hussam Mady b, Qing Lan c, Mona Melhem b, and Judy Mumford d.
    <...

  6. Supporting Lower-Achieving Seven- and Eight-Year-Old Children with Place Value Understandings

    ERIC Educational Resources Information Center

    Bailey, Judy

    2015-01-01

    Children can sometimes appear to understand a concept such as place value without really having a deep understanding. Judy Bailey stresses the importance of listening carefully to children to identify their current understandings and then building on them systematically, using a range of materials, to promote a deep conceptual understanding. This…

  7. The Japan Conference on English for Specific Purposes Proceedings (Aizuwakamatsu City, Fukushima, November 8, 1997).

    ERIC Educational Resources Information Center

    Orr, Thomas, Ed.

    The 13 papers archived here represent a sampling of the 23 presentations approved for the Japan Conference on English for Specific Purposes (ESP): "An Overview of ESP in the 1990s" (Tony Dudley-Evans); "'Easifying' ESP Texts for EFL Science Majors" (Judy Noguchi); "From Non-Communicative Exercises to Technical Writing: Profile of a Two-Semester…

  8. John Dewey and the Art of Teaching: Toward Reflective and Imaginative Practice

    ERIC Educational Resources Information Center

    Simpson, Douglas J.; Jackson, Michael J. B.; Aycock, Judy C.

    2004-01-01

    "John Dewey and the Art of Teaching: Toward Reflective and Imaginative Practice" is an engaging and accessible introduction to the art of teaching as seen through the eyes of John Dewey. Authors Douglas J. Simpson, Michael J. B. Jackson, and Judy C. Aycock provide a lucid interpretation of the complexities and art of teaching in contemporary…

  9. 75 FR 38868 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-06

    ... Bureau of the Public Debt Proposed Collection: Comment Request ACTION: Notice and request for comments... 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the Bureau of the Public Debt within the...: Direct all written comments to Bureau of the Public Debt, Judi Owens, 200 Third Street, A4-A,...

  10. 75 FR 5372 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-02

    ... Bureau of the Public Debt Proposed Collection: Comment Request ACTION: Notice and request for comments... 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A)). Currently the Bureau of the Public Debt within the... of consideration. ] ADDRESSES: Direct all written comments to Bureau of the Public Debt, Judi...