Science.gov

Sample records for kokanee enhancement feasibility

  1. Using 3D Acoustic Telemetry to Assess the Response of Resident Salmonids to Strobe Lights in Lake Roosevelt, Washington; Chief Joseph Kokanee Enhancement Feasibility Study, Annual Report 2001-2002.

    SciTech Connect

    Perry, Russlee; Farley, M.; Hansen, Gabriel

    2003-01-01

    In 1995, the Chief Joseph Kokanee Enhancement Project was established to mitigate the loss of anadromous fish due to the construction of Chief Joseph and Grand Coulee dams. The objectives of the Chief Joseph Enhancement Project are to determine the status of resident kokanee (Oncorhynchus nerka) populations above Chief Joseph and Grand Coulee dams and to enhance kokanee and rainbow trout (Oncorhynchus mykiss) populations. Studies conducted at Grand Coulee Dam documented substantial entrainment of kokanee through turbines at the third powerhouse. In response to finding high entrainment at Grand Coulee Dam, the Independent Scientific Review Panel (ISRP) recommended investigating the use of strobe lights to repel fish from the forebay of the third powerhouse. Therefore, our study focused on the third powerhouse and how strobe lights affected fish behavior in this area. The primary objective of our study was to assess the behavioral response of kokanee and rainbow trout to strobe lights using 3D acoustic telemetry, which yields explicit spatial locations of fish in three dimensions. Our secondary objectives were to (1) use a 3D acoustic system to mobile track tagged fish in the forebay and upriver of Grand Coulee Dam and (2) determine the feasibility of detecting fish using a hydrophone mounted in the tailrace of the third powerhouse. Within the fixed hydrophone array located in the third powerhouse cul-de-sac, we detected 50 kokanee and 30 rainbow trout, accounting for 47% and 45% respectively, of the fish released. Kokanee had a median residence time of 0.20 h and rainbow trout had a median residence time of 1.07 h. We detected more kokanee in the array at night compared to the day, and we detected more rainbow trout during the day compared to the night. In general, kokanee and rainbow trout approached along the eastern shore and the relative frequency of kokanee and rainbow trout detections was highest along the eastern shoreline of the 3D array. However, because we

  2. Chief Joseph Kokanee Enhancement Project : Confederated Tribes of the Colville Reservaton 1997 Annual Report.

    SciTech Connect

    LeCaire, Richard

    1998-01-01

    In the early 1980's the Confederated Tribes of the Colville Reservation, the Spokane Tribe of Indians and the Washington Dept. of Fish and Wildlife developed a management plan for Lake Roosevelt on the restoration and enhancement of kokanee salmon populations using hatchery out plants and the restoration of natural spawning runs. The plan was incorporated into the Northwest Power Planning Council (NPPC) in their 1987 Columbia Basin Fish and Wildlife program as partial mitigation for hydropower caused fish losses resulting from the construction of Grand Coulee Dam. The Chief Joseph Kokanee Enhancement Project, as part of a basin wide effort, is evaluating the status of the natural production kokanee in streams tributary to Lakes Roosevelt and Rufus Woods and is examining entrainment through Grand Coulee Dam. The goal of this project is the protection and enhancement of the natural production kokanee in these two lakes. The project is currently collecting data under four phases or parts. Since 1991, Lake Whatcom Washington origin kokanee have been planted in considerable numbers into the waters of Lake Roosevelt. A natural production kokanee fishery has persisted in the lake since the early 1970's(Cash, 1995), (Scholz, 1991). Historical information alludes to wild Kokanee production in the San Poil River, Nespelem River, Big Sheep Creek, Ora-Pa-Ken Creek, Deep Creek and Onion Creeks. The genetic makeup of the fish within the fishery is unknown, as is their contribution to the fishery. The level of influence by the hatchery out planted stock on wild fish stocks is unknown as well. Project outcomes will indicate the genetic fitness for inclusion of natural production kokanee stocks into current Bonneville Power Administration funded hatchery programs. Other findings may determine contribution/interaction of/between wild/hatchery kokanee stocks found in the waters of Lake Franklin D. Roosevelt.

  3. Chief Joseph Kokanee Enhancement Project; Strobe Light Deterrent Efficacy Test and Fish Behavior Determination at the Grand Coulee Dam Third Powerplant Forebay, 2004-2005 Annual Report.

    SciTech Connect

    Johnson, R.; McKinstry, C.; Cook, C.

    2005-02-01

    This report documents a four-year study(a) to assess the efficacy of a prototype strobe light system to elicit a negative phototactic response in kokanee (Oncorhynchus nerka kennerlyi) and rainbow trout (O. mykiss) at the entrance to the forebay of the third powerplant at Grand Coulee Dam. The work was conducted for the Bonneville Power Administration, U.S. Department of Energy, by Pacific Northwest National Laboratory (PNNL) in conjunction with the Confederated Tribes of the Colville Reservation (Colville Confederated Tribes). In this report, emphasis is placed on the methodology and results associated with the fourth project year and compared with findings from the previous years to provide an overall project summary. Since 1995, the Colville Confederated Tribes have managed the Chief Joseph Kokanee Enhancement Project as part of the Northwest Power and Conservation Council Fish and Wildlife Program. Project objectives have focused on understanding natural production of kokanee (a land-locked sockeye salmon) and other fish stocks in the area above Grand Coulee and Chief Joseph dams on the Columbia River (Figure S.1). A 42-month investigation from 1996 to 1999 determined that from 211,685 to 576,676 fish, including kokanee and rainbow trout, were entrained annually at Grand Coulee Dam. Analysis of the data found that 85% of the total entrainment occurred at the dam's third powerplant. Because these entrainment rates represent a significant loss to the tribal fisheries upstream of the dam, they have been judged unacceptable to fishery managers responsible for perpetuating the fishery in Lake Roosevelt. In an effort to reduce fish entrainment rates, the scope of work for the Chief Joseph Kokanee Enhancement Project was modified in 2001 to include a multiyear study of the efficacy of using strobe lights to deter fish from entering the third powerplant forebay. Pacific Northwest National Laboratory initiated the four-year study in collaboration with Colville Tribal

  4. Chief Joseph Kokanee Enhancement Project : Strobe Light Deterrent Efficacy Test and Fish Behavior Determination at Grond Coulee Dam Third Powerplant Forebay.

    SciTech Connect

    Simmons, M.A.; McKinstry, C.A.; Simmons, C.S.

    2002-01-01

    Since 1995, the Colville Confederated Tribes have managed the Chief Joseph Kokanee Enhancement Project as part of the Northwest Power Planning Council's (NWPPC) Fish and Wildlife Program. Project objectives have focused on understanding natural production of kokanee (a land-locked sockeye salmon) and other fish stocks in the area above Grand Coulee and Chief Joseph Dams on the Columbia River. A 42-month investigation concluded that entrainment at Grand Coulee Dam ranged from 211,685 to 576,676 fish annually. Further analysis revealed that 85% of the total entrainment occurred at the dam's third powerplant. These numbers represent a significant loss to the tribal fisheries upstream of the dam. In response to a suggestion by the NWPPC's Independent Scientific Review Panel, the scope of work for the Chief Joseph Kokanee Enhancement Project was expanded to include a multiyear pilot test of a strobe light system to help mitigate fish entrainment. This report details the work conducted during the first year of the study by researchers of the Colville Confederated Tribes in collaboration with the Pacific Northwest National Laboratory (PNNL). The objective of the study was to determine the efficacy of a prototype strobe light system to elicit a negative phototactic response in kokanee and rainbow trout. Analysis of the effect of strobe lights on the distribution (numbers) and behavior of kokanee and rainbow trout was based on 51, 683 fish targets detected during the study period (June 30 through August 1, 2001). Study findings include the following: (1) Analysis of the count data indicated that significantly more fish were present when the lights were on compared to off. This was true for both the 24-hr tests as well as the 1-hr tests. Powerplant discharge, distance from lights, and date were significant factors in the analysis. (2) Behavioral results indicated that fish within 14 m of the lights were trying to avoid the lights by swimming across the lighted region or

  5. Chief Joseph Kokanee Enhancement Project; Strobe Light Deterrent Efficacy Test and Fish Behavior Determination at the Grand Coulee Dam Third Powerplant Forebay, 2003-2004 Annual Report.

    SciTech Connect

    Simmons, M.; McKinstry, C.; Cook, C.

    2004-01-01

    Since 1995, the Confederated Tribes of the Colville Reservation (Colville Confederated Tribes) have managed the Chief Joseph Kokanee Enhancement Project as part of the Northwest Power Planning Council (NWPPC) Fish and Wildlife Program. Project objectives have focused on understanding natural production of kokanee (a land-locked sockeye salmon) and other fish stocks in the area above Grand Coulee and Chief Joseph Dams on the Columbia River. A 42-month investigation from 1996 to 1999 determined that from 211,685 to 576,676 fish were entrained annually at Grand Coulee Dam. Analysis of the entrainment data found that 85% of the total entrainment occurred at the dam's third powerplant. These numbers represent a significant loss to the tribal fisheries upstream of the dam. In response to a suggestion by the NWPPC Independent Scientific Review Panel, the scope of work for the Chief Joseph Kokanee Enhancement Project was expanded to include a multiyear pilot test of a strobe light system to help mitigate fish entrainment. This report details the work conducted during the third year of the strobe light study by researchers of the Colville Confederated Tribes in collaboration with the Pacific Northwest National Laboratory. The objective of the study is to determine the efficacy of a prototype strobe light system to elicit a negative phototactic response in kokanee and rainbow trout under field conditions. The prototype system consists of six strobe lights affixed to an aluminum frame suspended 15 m vertically underwater from a barge secured in the center of the entrance to the third powerplant forebay. The lights, controlled by a computer, illuminate a region directly upstream of the barge. The 2003 study period extended from June 16 through August 1. Three light treatments were used: all six lights on for 24 hours, all lights off for 24 hours, and three of six lights cycled on and off every hour for 24 hours. These three treatment conditions were assigned randomly within a

  6. Chief Joseph Kokanee Enhancement Project; Strobe Light Deterrent Efficacy Test and Fish Behavior Determination at the Grand Coulee Dam Third Powerplant Forebay, 2002-2003 Annual Report.

    SciTech Connect

    Johnson, R.; McKinstry, C.; Simmons, C.

    2003-01-01

    Since 1995, the Confederated Tribes of the Colville Reservation (Colville Confederated Tribes) have managed the Chief Joseph Kokanee Enhancement Project as part of the Northwest Power Planning Council (NWPPC) Fish and Wildlife Program. Project objectives have focused on understanding natural production of kokanee (a land-locked sockeye salmon) and other fish stocks in the area above Grand Coulee and Chief Joseph Dams on the Columbia River. A 42-month investigation concluded that entrainment at Grand Coulee Dam ranged from 211,685 to 576,676 fish annually. Further analysis revealed that 85% of the total entrainment occurred at the dam's third powerplant. These numbers represent a significant loss to the tribal fisheries upstream of the dam. In response to a suggestion by the NWPPC Independent Scientific Review Panel, the scope of work for the Chief Joseph Kokanee Enhancement Project was expanded to include a multiyear pilot test of a strobe light system to help mitigate fish entrainment. This report details the work conducted during the second year of the study by researchers of the Colville Confederated Tribes in collaboration with the Pacific Northwest National Laboratory. The 2002 study period extended from May 18 through July 30. The objective of the study was to determine the efficacy of a prototype strobe light system to elicit a negative phototactic response in kokanee and rainbow trout. The prototype system consisted of six strobe lights affixed to an aluminum frame suspended vertically underwater from a barge secured in the center of the entrance to the third powerplant forebay. The lights, controlled by a computer, were aimed to illuminate a specific region directly upstream of the barge. Three light level treatments were used: 6 of 6 lights on, 3 of 6 lights on, and all lights off. These three treatment conditions were applied for an entire 24-hr day and were randomly assigned within a 3-day block throughout the study period. A seven-transducer splitbeam

  7. Chief Joseph Kokanee Enhancement Project; Strobe Light Deterrent Efficacy Test and Fish Behavior Determination at Grand Coulee Dam Third Powerplant Forebay, 2005-2006 Annual Report.

    SciTech Connect

    Simmons, M.; Johnson, Robert; McKinstry, C.

    2006-03-01

    The construction of Grand Coulee and Chief Joseph dams on the Columbia River resulted in the complete extirpation of the anadromous fishery upstream of these structures. Today, this area is totally dependent upon resident fish resources to support local fisheries. The resident fishing is enhanced by an extensive stocking program for target species in the existing fishery, including kokanee (Oncorhynchus nerka kennerlyi) and rainbow trout (O. mykiss). The kokanee fishery in Lake Roosevelt has not been meeting the return goals set by fisheries managers despite the stocking program. Investigations of physical and biological factors that could affect the kokanee population found predation and entrainment had a significant impact on the fish population. In 1999 and 2000, walleye (Sander vitreum) consumed between 15% and 9%, respectively, of the hatchery kokanee within 41 days of their release, while results from a study in the late 1990s estimated that entrainment at Grand Coulee Dam could account for up to 30% of the total mortality of the stocked fish. To address the entrainment loss, the Bonneville Power Administration commissioned a study to determine if fish would avoid areas illuminated by strobe lights in the forebay of the third powerplant. This work was conducted by Pacific Northwest National Laboratory (PNNL) in conjunction with the Confederated Tribes of the Colville Reservation (Colville Confederated Tribes). From 2002 through 2004, six strobe lights were suspended in the center of the opening to the third powerplant forebay during summer months. Results from those studies indicated that fish appeared to be attracted to the illuminated area but only at night and when flow conditions within the third powerplant forebay were minimal. However, small but consistent results from these studies indicated that under high flow conditions, fish might be avoiding the lights. The 2005 study was designed to examine whether, under high flow conditions near the penstock

  8. Chief Joseph Kokanee Enhancement Project; Characterization of Pump Flow at the Grand Coulee Dam Pumping Station for Fish Passage, 2004-2005 Final Report.

    SciTech Connect

    Carlson, T.; Duncan, J.; Johnson, R.

    2005-03-01

    This report describes a study conducted by Pacific Northwest National Laboratory (PNNL) for the Bonneville Power Administration to characterize the conditions fish experience when entrained in pump flow at the Grand Coulee Dam. PNNL conducted field studies at Grand Coulee Dam in 2004 using the Sensor Fish to measure the acceleration and pressure conditions that might be experienced by fish that pass through pumps at Grand Coulee Dam's Pump-Generating Plant and are transported up into the feeder canal leading to Banks Lake. The probability that fish would be struck by the Pump-Generating Plant's new nine-bladed turbines was also estimated. Our measurements showed relatively low turbulence except in the immediate vicinity of the runner environment. The lowest and highest pressures experienced by the Sensor Fish were 6.4 and 155 psi (the pressure gauge saturated at 155 psi). The probability of strike was also calculated, based on the average length of hatchery-reared juvenile kokanee (land-locked sockeye). Strike probabilities ranged from 0.0755 for 2.36-inch fish to 0.3890 for 11.8-inch fish. The probability of strike estimates indicate that the majority (77%) of recently released hatchery kokanee would be carried through the test pump without being struck and most likely with low risk of injury resulting from pressure and turbulence exposure. Of the 23% that might be struck it is expected that 60% would arrive in Banks Lake without visible external injuries. Thus more than 90% of entrained fish could be expected to arrive in Banks Lake without significant injury, assuming that no kokanee were injured or killed by pressure exposure during passage.

  9. Effect of the Operation of Kerr and Hungry Horse Dams on the Reproductive Success of Kokanee in the Flathead System; Technical Addendum to the Final Report.

    SciTech Connect

    Beattie, Will; Tohtz, Joel

    1990-03-01

    This addendum to the Final Report presents results of research on the zooplankton and fish communities of Flathead Lade. The intent of the Study has been to identify the impacts of hydroelectric operations at Kerr and Hungry Horse Dam on the reproductive success of kokanee an to propose mitigation for these impacts. Recent changes in the trophic ecology of the lake, have reduced the survival of kokanee. In the last three year the Study has been redirected to identify, if possible, the biological mechanisms which now limit kokanee survival, and to test methods of enhancing the kokanee fishery by artificial supplementation. These studies were necessary to the formulation of mitigation plans. The possibility of successfully rehabilitating the kokanee population, is the doubt because of change in the trophic ecology of the system. This report first presents the results of studies of the population dynamics of crustacean zooplankton, upon which planktivorous fish depend. A modest effort was directed to measuring the spawning escapement of kokanee in 1988. Because of its relevance to the study, we also report assessments of 1989 kokanee spawning escapement. Hydroacoustic assessment of the abundance of all fish species in Flathead Lake was conducted in November, 1988. Summary of the continued efforts to document the growth rates and food habits of kokanee and lake whitefish are included in this report. Revised kokanee spawning and harvest estimates, and management implications of the altered ecology of Flathead Lake comprise the final sections of this addendum. 83 refs., 20 figs., 25 tabs.

  10. Effect of the Operation of Kerr and Hungry Horse Dams on the Reproductive Success of Kokanee in the Flathead System, 1987 Final Report.

    SciTech Connect

    Beattie, Will; Zubik, Raymond; Clancey, Patrick

    1988-05-01

    effects of hydroelectric operations on the reproductive success of kokanee in the Flathead system have been ongoing since 1980. Results of these studies have been published in a series of annual progress reports which are detailed in Appendix G. The reports summarize spawning site inventories and spawning escapement, egg and alevin mortality rates and the mechanisms by which water level fluctuations influence mortality, creel surveys, and investigation of the population dynamics of Flathead kokanee. The Region 1 offices of the Montana Department of Fish, Wildlife and Parks distribute this material to the scientific community and the general public. Until recently, it was considered feasible to recover losses to the Flathead kokanee fishery by enhancing and diversifying natural reproduction. But the establishment of opossum shrimp (M. relicta) in Flathead Lake has reduced the availability of zooplankton forage in the spring and summer, and may reduce the viability of juvenile kokanee. In 1986, research was redirected to quantify this competitive interaction and to investigate artificial means of enhancing the kokanee fishery. The average density of mysid shrimp in Flathead Lake has increased to 108/m{sup 2} in 1987, and at some locations density exceeds 500/m2. Mysid grazing pressure has delayed the pulse of zooplankton production in the spring and reduced zooplankton standing crop in the summer. Cladocerans such as Daphnia thorata, the preferred food of kokanee of all ages, are the most markedly affected species. The peak density of D. thorata in the summer has declined from 4.8/liter in 1983 to O.9/liter in 1987. Growth rates of underyearling and yearling kokanee have declined, apparently as a result of the reduction in their food supply. Spawning escapement has also declined, falling from 150,000 in 1985. to 25,000 in 1986, to 600 in 1987. Fry-to-adult survival has declined from 2.5 percent to near zero. The causes of high mortality, and which age-classes are most

  11. Exoskeleton for Soldier Enhancement Systems Feasibility Study

    SciTech Connect

    Jansen, J.F.

    2000-09-28

    The development of a successful exoskeleton for human performance augmentation (EHPA) will require a multi-disciplinary systems approach based upon sound biomechanics, power generation and actuation systems, controls technology, and operator interfaces. The ability to integrate key components into a system that enhances performance without impeding operator mobility is essential. The purpose of this study and report are to address the issue of feasibility of building a fieldable EHPA. Previous efforts, while demonstrating progress and enhancing knowledge, have not approached the level required for a fully functional, fieldable system. It is doubtless that the technologies required for a successful exoskeleton have advanced, and some of them significantly. The question to be addressed in this report is have they advanced to the point of making a system feasible in the next three to five years? In this study, the key technologies required to successfully build an exoskeleton have been examined. The primary focus has been on the key technologies of power sources, actuators, and controls. Power sources, including internal combustion engines, fuel cells, batteries, super capacitors, and hybrid sources have been investigated and compared with respect to the exoskeleton application. Both conventional and non-conventional actuator technologies that could impact EHPA have been assessed. In addition to the current state of the art of actuators, the potential for near-term improvements using non-conventional actuators has also been addressed. Controls strategies, and their implication to the design approach, and the exoskeleton to soldier interface have also been investigated. In addition to these key subsystems and technologies, this report addresses technical concepts and issues relating to an integrated design. A recommended approach, based on the results of the study is also presented.

  12. Environmental Assessment on Construction of the Cabinet Gorge Kokanee Hatchery.

    SciTech Connect

    United States. Bonneville Power Administration.

    1984-10-01

    Bonneville Power Administration, the Washington Water Power Company, and Idaho Department of Fish and Game plan to enter into a cooperative cost-sharing agreement for the design, construction, operation, and maintenance of a kokanee hatchery in northern Idaho. The proposed hatchery shall supplement mitigation of adverse federal and non-federal hydroelectric and nonhydroelectric impacts. Hydroelectric impacts were primarily degradation of the Lake Pend Oreille shoreline kokanee habitat and blockage of migrating Clark Fork River kokanee. The introduction and establishment of Mysis relicta, the opossum shrimp, created further adverse effects on the kokanee fishery. The proposed hatchery will produce 20 million advanced-stage kokanee fry which will restore the Lake Pend Oreille kokanee fishery level to 744,000 harvestable adults after the first 5 years of operation. 6 references, 4 figures.

  13. Dworshak Reservoir Kokanee Population Monitoring, Annual Report 2001.

    SciTech Connect

    Maiolie, Melo; Stark, Eric

    2003-03-01

    Onsite testing of strobe lights was conducted to determine if they repelled kokanee Oncorhynchus nerka away from the turbine intakes at Dworshak Dam. We tested a set of nine strobe lights flashing at a rate of 360 flashes/min placed near the intake of a 90 mW turbine. A split-beam echo sounder was used to determine the effect of strobe light operation on fish density (thought to be mostly kokanee) in front of the turbine intakes. On five nights between December 2001 and January 2002, fish density averaged 110 fish/ha when no lights were flashing. Mean density dropped to 13 fish/ha when the strobe lights were turned on during five additional nights of sampling. This 88% decline in density was significant at the P = 0.009 level of significance based on a paired Student's t test. There appeared to be no tendency for fish to habituate to the lights during the night. Test results indicate that a single set of nine lights may be sufficient to repel kokanee from a turbine intake during the night. We also used split-beam hydroacoustics to monitor the kokanee population in Dworshak Reservoir during 2001. Estimated abundance of kokanee has continued to increase since the spring of 1996 when high entrainment losses occurred. Based on hydroacoustic surveys, we estimated 3,276,000 kokanee in Dworshak Reservoir in early July 2001. This included 2,069,000 age-0 kokanee (90% CI {+-} 16.4%), 801,000 age-1 kokanee (90% CI {+-} 17.8%), and 406,000 age-2 kokanee (90% CI {+-} 20.5%). Entrainment sampling was also conducted with split-beam hydroacoustics a minimum of one continuous 24 h period per month. The highest entrainment rates occurred at night with lower discharges and shallower intake depths. Fish movement patterns suggested that they swam 'at will' in front of the intakes and may have chosen to move into the turbine intakes. Based on monthly hydroacoustic sampling in the forebay, we found that kokanee density was low in July and August during a period of high discharge

  14. Dworshak Reservoir Kokanee Population Monitoring: Project Progress Report, 1999 Annual Report.

    SciTech Connect

    Maiolie, Melo; Vidergar, Dmitri T.; Harryman, Bill

    2001-08-01

    We used split-beam hydroacoustics and trawling to monitor the kokanee Oncorhynchus nerka population in Dworshak Reservoir during 1999. Estimated abundance of kokanee has continued to increase since the high entrainment losses in the spring of 1996. Based on hydroacoustic surveys, we estimated 1,545,000 kokanee and rainbow trout O. mykiss in Dworshak Reservoir during July 1999. This included 1,144,000 age-0 kokanee (90% CI {+-} 42%), 212,000 age-1 kokanee (90% CI {+-} 15%), and 189,000 age-2 kokanee and stocked rainbow trout (90% CI {+-} 39%). Rainbow trout could not be distinguished from the age-2 kokanee in the echograms since they were of similar size. Age-0 kokanee ranged in length from 40 mm to 90 mm, age-1 from 193 mm to 212 mm, and age-2 kokanee from 219 mm to 336 mm. These sizes indicated kokanee are still growing well. Discharge of water from Dworshak Dam during 1999 did not stop the expansion of the kokanee population based on these results. Counts of spawning kokanee in four tributary streams exceeded 11,000 fish. This index also showed a marked increase from last year's 660 spawning kokanee or the 1997 total of 144 spawning kokanee.

  15. Temperature and depth mediate resource competition and apparent competition between Mysis diluviana and kokanee.

    PubMed

    Schoen, Erik R; Beauchamp, David A; Buettner, Anna R; Overman, Nathanael C

    2015-10-01

    In many food webs, species in similar trophic positions can interact either by competing for resources or boosting shared predators (apparent competition), but little is known about how the relative strengths of these interactions vary across environmental gradients. Introduced Mysis diluviana shrimp interact with planktivorous fishes such as kokanee salmon (lacustrine Oncorhynchus nerka) through both of these pathways, and effective management depends on understanding which interaction is more limiting under different conditions. An "environmental matching" hypothesis predicts the ecological impacts of Mysis are maximized under cool conditions near its thermal optimum. In addition, we hypothesized Mysis is more vulnerable to predation by lake trout in relatively shallow waters, and therefore Mysis enhances lake trout density and limits kokanee through apparent competition more strongly in shallower habitats. We tested whether these hypotheses could explain food web differences between two connected lake basins, one relatively shallow and the other extremely deep. The shallower basin warmed faster, thermally excluded Mysis from surface waters for 75% longer, and supported 2.5-18 times greater seasonal production of cladoceran zooplankton than the deeper basin, standardized by surface area. Mysis consumed 14-22% less zooplankton in the shallower basin, and lower ratios of total planktivore consumption to zooplankton production (C:P) indicated less potential for resource competition with kokanee, consistent with environmental matching. Lake trout diets contained more Mysis in the shallower basin and at shallower sampling sites within both basins. The catch rate of lake trout was seven times greater and the predation risk for kokanee was 4-5 times greater in the shallower basin than in the deeper basin, consistent with stronger apparent competition in shallower habitats. Understanding how the strengths of these interactions are mediated by temperature and depth would

  16. Hungry Horse Dam Fisheries Mitigation; Kokanee Stocking and Monitoring in Flathead Lake, 1996 Progress Report.

    SciTech Connect

    Carty, Daniel; Knoetek, W. Ladd Hansen, Barry

    1997-06-01

    Kokanee salmon Oncorhynchus nerka were introduced into Flathead Lake in 1916. The kokanee population declined in the 1960s and 1970s, and kokanee disappeared from Flathead Lake in the late 1980s. Their disappearance has been attributed to the long-term effects of the construction and operation of Hungry Horse and Kerr dams, excessive harvest by anglers, and changes in the lake food web induced by the introduction of opossum shrimp Mysis relicta. Attempts to reestablish kokanee in the Flathead Lake ecosystem between 1988 and 1991 were unsuccessful. In 1991, Montana Fish, Wildlife and Parks (MFWP) and the Confederated Salish and Kootenai Tribes (CSKT) wrote a mitigation plan to restore kokanee to Flathead Lake. In 1993, MFWP, CSKT, and the U.S. Fish and Wildlife Service wrote a mitigation implementation plan that initiated a 5-year test program to use hatchery-reared fish to reintroduce kokanee to the lake. Stocking hatchery-reared kokanee into Flathead Lake began in 1993; the 5-year {open_quotes}kokanee test{close_quotes} started in 1994 and is scheduled to continue through 1998. The annual stocking objective is 1 million yearling kokanee (6-8 in long). Criteria used to evaluate the success of the 5-year test are (1) 30% survival of kokanee 1 year after stocking, (2) yearling-to-adult survival of 10%, and (3) annual harvest of 50,000 kokanee ({ge} 11 in) and fishing effort {ge} 100,000 angler hours.

  17. Feasibility Study: Potential Enhancements for the LLNL Renewables Website

    SciTech Connect

    Kearns, F; Krawchuk, M; Moritz, M; Stephens, S; Goldstein, N

    2008-01-25

    This feasibility study investigates additional improvements/extensions to the LLNL Renewables Website. Currently, the Renewables Website focuses on wind energy in California. Future enhancements will include other renewable energy sources. The extensions described below are focused along two separate yet related avenues: (1) Forecasting wildfire risk in the regions of California where new development may occur, as a part of the 'Million Solar Roofs' program. (2) Gaining a better understanding of the ecological components and potential of biofuels from forests in California. These two avenues are further described in the report. Following is a technical description of the Center for Fire Research and Outreach computing and web service capabilities.

  18. Kokanee Stock Status and Contribution Cabinet Gorge Hatchery, Lake Pend Oreille, Idaho, 1988 Annual Progress Report.

    SciTech Connect

    Bowles, Edward C.

    1989-02-01

    The kokanee Oncorhynchus nerka rehabilitation program for Lake Pend Oreille continued to show progress during 1988. Estimated kokanee abundance in early September was 10.2 million fish. This estimate is 70% higher than 1987 and 140% higher than the populations's low point in 1986. Increased population size over the past two years is the result of two consecutive strong year classes produced from high recruitment of hatchery and wild fry. High recruitment of wild fry in 1988 resulted from good parental escapement (strong year class) in 1987 and relatively high fry survival. Hatchery fry made up 51% of total fry recruitment (73% of total fry biomass), which is the largest contribution since hatchery supplementation began in the 1970s. High hatchery fry abundance resulted from a large release (13 million fry) from Cabinet Gorge Hatchery and excellent fry survival (29%) during their first summer in Lake Pend Oreille. Improved fry release strategies enhanced survival, which doubled from 1987 to 1988 and was ten times higher than survival in 1986. Our research goal is to maintain 30% survival so we are very optimistic, but need to replicate additional years to address annual variability. 27 refs., 24 figs., 3 tabs.

  19. Kokanee Impacts Assessment and Monitoring on Lake Pend Oreille, Idaho, Annual Progress Report for October 1995-September 1996.

    SciTech Connect

    Maiolie, Melo A.

    1998-09-01

    The purpose of this project was to Monitor Lake Pend Oreille's kokanee Oncorhynchus nerka kennerlyi population. Data will serve as a baseline for evaluating the benefits of a higher winter lake level beginning in 1996. We estimated the kokanee population in Lake Pend Oreille using a Hauser-type midwater trawl during August 1995 and September 1996. Population estimates in 1995 were 4.55 million age-0 kokanee, 2.87 million age-1 kokanee, 1.52 million age-2 kokanee, 0.74 million age-3 kokanee, 0.15 million age-4 kokanee, and 42,000 age-5 kokanee. Population estimates in 1996 were 5.42 million age-0 kokanee, 3.57 million age-1 kokanee, 3.17 million age-2 kokanee, 0.67 million age-3 kokanee, 0.44 million age-4 kokanee, and no age-5 kokanee. These were two of the highest total populations of kokanee since trawling began in 1977; largely due to high numbers of young kokanee. The densities of age-4 and 5 kokanee (which make up the bulk of the fishery), however, were the lowest on record in 1995 and average in 1996. We also surveyed traditional shoreline and tributary spawning areas. Counts of kokanee spawning in tributaries during 1995 were relatively consistent with previous years (6,261 kokanee). Counts of spawners along the shorelines reached a new record low of only 74 kokanee; a 93 percent decline from 1994. During December 1996, both counts dropped to their lowest point on record. Only 49 fish were seen spawning along the shorelines, and only 819 fish were seen in tributary streams. These low counts may have been partially due to higher lake levels during the spawning seasons. Higher than normal lake levels made additional gravel available for kokanee spawning in many areas of the lake. Possibly this caused kokanee to spread along the shorelines and reduced the spawner counts. Kokanee fry that had been fin clipped and stocked at the Cabinet Gorge Fish Hatchery Ladder in 1991 and 1992 returned at a rate of 0.27% and 0.14% once they matured. This return rate was much

  20. Lake Roosevelt Fisheries Monitoring Program; Artificial Imprinting and Smoltification in Juvenile Kokanee Salmon Implications for Operating Lake Roosevelt Kokanee Salmon Hatcheries; 1994 Supplement Report.

    SciTech Connect

    Tilson, Mary Beth; Scholz, Allan T.; White, Ronald J.

    1995-02-01

    At the kokanee salmon hatcheries on Lake Roosevelt, constructed as partial mitigation for effects from Grand Coulee Dam, adult returns have been poor. The reason may be in the imprinting or in the smoltification. A study was initiated in 1992 to determine if there was a critical period for thyroxine induced alfactory imprinting in kokanee salmon; experiments were conducted on imprinting to morpholine and phenethyl alcohol. Other results showed that chemical imprinting coincided with elevated thyroxine levels in 1991 kokanee exposed to synthetic chemicals in 1992. In this report, imprinting experiments were repeated; results showed that imprinting occurred concomitant with elevated thyroxine levels in 1991 kokanee exposed to synthetic chemicals in 1992 and tested in 1994 as age 3 spawners. Imprinting also occurred at the same time as thyroxine peaks in 1992 kokanee exposed to synthetic chemicals in 1993 and tested as age 2 spawners. In both groups fish that had the highest whole body thyroxine content (swimup stage) also had the highest percentage of fish that were attracted to their exposure odor in behavioral tests. So, kokanee salmon imprinted to chemical cues during two sensitive periods during development, at the alevin/swimup and smolt stages. A field test was conducted in Lake Roosevelt on coded wire tagged fish. Smoltification experiments were conducted from 1992 to 1994. Recommendations are made for the Lake Roosevelt kokanee hatcheries.

  1. Impacts of Water Level Fluctuations on Kokanee Reproduction in Flathead Lake; Effects of Operation of Kerr and Hungry Horse Dam on Reproductive Success, 1983 Annual Report.

    SciTech Connect

    Decker-Hess, Janet; McMullin, Steve L.

    1983-11-01

    ) found live eggs and fry only in shoreline spawning areas wetted by groundwater seeps. Impacts of the operation of Kerr Dam on lakeshore spawning have not been quantified. Recent studies have revealed that operation of Hungry Horse Dam severely impacted successful kokanee spawning and incubation in the Flathead River above Flathead Lake (Graham et al. 1980, McMullin and Graham 1981, Fraley and Graham 1982 and Fraley and McMullin 1983). Flows from Hungry Horse Dam to enhance kokanee reproduction in the river system have been voluntarily met by the Bureau of Reclamation since 1981. In lakeshore spawning areas in other Pacific Northwest systems, spawning habitat for kokanee and sockeye salmon was characterized by seepage or groundwater flow where suitable substrate composition existed (Foerster 1968). Spawning primarily occurred in shallower depths (<6 m) where gravels were cleaned by wave action (Hassemer and Rieman 1979 and 1980, Stober et al. 1979a). Seasonal drawdown of reservoirs can adversely affect survival of incubating kokanee eggs and fry spawned in shallow shoreline areas. Jeppon (1955 and 1960) and Whitt (1957) estimated 10-75 percent kokanee egg loss in shoreline areas of Pend Oreille Lake, Idaho after regulation of the upper three meters occurred in 1952. After 20 years of operation, Bowler (1979) found Pend Oreille shoreline spawning to occur in fewer areas with generally lower numbers of adults. In studies on Priest Lake, Idaho, Bjornn (1957) attributed frozen eggs and stranded fry to winter fluctuations of the upper three meters of the lake. Eggs and fry frozen during winter drawdown accounted for a 90 percent loss to shoreline spawning kokanee in Donner Lake, California (Kimsey 1951). Stober et al. (1979a) determined irrigation drawdown of Banks Lake, Washington reduced shoreline survival during five of the seven years the system was studied. The goal of this phase of the study was to evaluate and document effects of the operation of Kerr Dam on kokanee

  2. Do predators influence the distribution of age-0 kokanee in a Colorado Reservoir?

    USGS Publications Warehouse

    Hardiman, J.M.; Johnson, B.M.; Martinez, P.J.

    2004-01-01

    Seasonal changes in reservoir conditions such as productivity, light, and temperature create spatiotemporal variation in habitat that may segregate or aggregate predators and prey, producing implications for the distribution, growth, and survival of fishes. We used hydroacoustics to document the diel vertical distribution of age-0 kokanee Oncorhynchus nerka relative to environmental gradients at Blue Mesa Reservoir, Colorado, during May-August of 2002. Temperature, light, and zooplankton density profiles were examined relative to foraging conditions for kokanee and their primary predator, lake trout Salvelinus namaycush. Age-0 kokanee displayed large diel vertical migrations in May despite the lack of an energetic advantage before reservoir stratification. Age-0 kokanee minimized near-surface foraging at this time, perhaps to avoid predation by visual predators, such as lake trout, in the well-lit surface waters. Strong reservoir stratification in midsummer appeared to provide a thermal refuge from lake trout that the kokanee exploited. By August vertical migrations were shallow and most kokanee remained in the epilimnion throughout the day. Although the energetic implications of the late-summer strategy are unclear, it appears that kokanee were responding to changes in their predator environment. A robust model for kokanee diel vertical migration across a range of systems should include a predator avoidance component.

  3. Assessment of environmental and economic feasibility of Enhanced Landfill Mining.

    PubMed

    Danthurebandara, Maheshi; Van Passel, Steven; Vanderreydt, Ive; Van Acker, Karel

    2015-11-01

    This paper addresses the environmental and economic performance of Enhanced Landfill Mining (ELFM). Based on life cycle assessment and life cycle costing, a detailed model is developed and is applied to a case study, i.e. the first ELFM project in Belgium. The environmental and economic analysis is performed in order to study the valorisation of different waste types in the landfill, such as municipal solid waste, industrial waste and total waste. We found that ELFM is promising for the case study landfill as greater environmental benefits are foreseen in several impact categories compared to the landfill's current situation (the 'Do-nothing' scenario). Among the considered processes, the thermal treatment process dominates both the environmental and economic performances of ELFM. Improvements in the electrical efficiency of thermal treatment process, the calorific value of refuse derived fuel and recovery efficiencies of different waste fractions lead the performance of ELFM towards an environmentally sustainable and economically feasible direction. Although the environmental and economic profiles of ELFM will differ from case to case, the results of this analysis can be used as a benchmark for future ELFM projects. PMID:25708403

  4. Kokanee Stock Status and Contribution of Cabinet Gorge Hatchery, Lake Pend Oreille, Idaho, 1987 Annual Progress Report.

    SciTech Connect

    Bowles, Edward C.

    1988-05-01

    Estimated kokanee Oncorhynchus nerka abundance in Lake Pend Oreille was 6.01 million during late summer 1987. This estimate is 40% higher than the 1986 estimate and is the second largest population estimate since 1977. Higher abundance is predominantly a result of enhanced fry survival and recruitment. Hatchery-reared fry contribution was 22% of total fry recruitment in 1987, compared to 8% in 1986, and resulted from a fivefold increase in survival. Much of this improvement can be attributed to the large (52 mm) fry produced at Cabinet Gorge Hatchery in 1987 and represents the first measurable contribution of the new hatchery to the kokanee rehabilitation program. Survival of hatchery-reared fry released into Clark Fork River was nearly one-half that of fry released into Sullivan Springs due to poor flow conditions and potentially high predation during migration from Cabinet Gorge Hatchery to Lake Pend Oreille. Wild fry survival was enhanced by early availability of forage (cladocern zooplankton) during fry emergence in late spring. Cladoceran production began three weeks earlier in 1987 than 1986, which resulted from reduced Mysis abundance and earlier thermal stratification of Lake Pend Oreille, which helped segregate cladocerans from mysid predation. Kokanee dry otolith coding was evaluated to provide a reliable long-term mark. Analysis of daily growth increments on otoliths was used successfully in 1987 to differentiate fry from various release sites. The technique will be refined during 1988 to include coding fry otoliths with water temperature fluctuations during hatchery residence. 23 refs., 20 figs., 2 tabs.

  5. Kokanee Stocking and Monitoring, Flathead Lake, 1993-1994 Annual Report.

    SciTech Connect

    Deleray, Mark; Fredenberg, Wade; Hansen, Barry

    1995-07-01

    One mitigation goal of the Hungry Horse Dam fisheries mitigation program, funded by the Bonneville Power Administration, is to replace lost production of 100,000 adult kokanee in Flathead Lake. The mitigation program calls for a five-year test to determine if kokanee can be reestablished in Flathead Lake. The test consists. of annual stocking of one million hatchery-raised yearling kokanee. There are three benchmarks for judging the success of the kokanee reintroduction effort: (1) Post-stocking survival of 30 percent of planted kokanee one year after stocking; (2) Yearling to adult survival of 10 percent (100,000 adult salmon); (3) Annual kokanee harvest of 50,000 or more fish per year by 1998, with an average length of 11 inches or longer for harvested fish, and fishing pressure of 100,000 angler hours or more. Kokanee were the primary sport fish species in the Flathead Lake fishery in the early 1900s, and up until the late 1980s when the population rapidly declined in numbers and then disappeared. Factors identified which influenced the decline of kokanee are the introduction of opossum shrimp (Mysis relicta), hydroelectric operations, overharvest through angling, and competition and/or predation by lake trout (Salvelinus namaycush) and lake whitefish (Coregonur clupeaformis). The purpose of this report was to summarize the stocking program and present monitoring results from the 1993 and 1994 field seasons. In June 1993, roughly 210,000 yearling kokanee were stocked into two bays on the east shore of Flathead Lake. Following stocking, we observed a high incidence of stocked kokanee in stomach samples from lake trout captured in areas adjacent to the stocking sites and a high percentage of captured lake trout containing kokanee. Subsequent monitoring concluded that excessive lake trout predation precluded significant survival of kokanee stocked in 1993. In June 1994, over 802,000 kokanee were stocked into Big Arm Bay. The combination of near optimum water

  6. Feasibility study of sedimentary enhanced geothermal systems using reservoir simulation

    NASA Astrophysics Data System (ADS)

    Cho, Jae Kyoung

    The objective of this research is to evaluate the preliminary feasibility of commercial geothermal projects, from a sedimentary reservoir with low permeability that requires productivity enhancement, using numerical reservoir simulation. The performance of a sedimentary geothermal reservoir is investigated in terms of reservoir hydraulics and thermal evolution. To build a reliable benchmark for simulation study, validation of the numerical reservoir model with respect to an analytical model is presented, and the process to achieve an acceptable match between the numerical and analytical solutions is described. The analytical model used in this study is based on the work of Gringarten (1978), which consists of a conceptual geothermal reservoir, considering an injection and production well doublet in a homogeneous porous media. A commercial thermal reservoir simulator (STARS from Computer Modeling Group, CMG) is used in this work for numerical modeling. In order to reproduce the analytical model results, the numerical simulation model is modified to include the same assumptions of the analytical model. Simulation model parameters that make the numerical results deviate from the analytical solution, such as the grid block size, time step and no-flow boundary are identified and investigated. An analytical tracer test model proposed by Shook (2000) is numerically modeled. This model allows us to predict the time when the temperature of the produced water decreases by capturing a tracer component at production well. Reservoir simulation models with different porosity and permeability distribution are tested to see the effects of reservoir inhomogeneity and anisotropy. In particular, premature thermal breakthrough due to the presence of high permeability streak in a reservoir model is simulated. In an effort to apply the knowledge we obtained from the analytical solutions, the effects of reservoir rock and water properties, as a function of pressure and temperature, are

  7. Kokanee Impacts Assessment and Monitoring of Lake Pend Oreille and Dworshak Reservoir, Idaho, 1994 Annual Report.

    SciTech Connect

    Fredericks, James P.; Elam, Steve; Maiolie, Melo A.

    1995-06-01

    In an effort to recover the declining kokanee Oncorhynchus nerka kennerlyi population in Lake Pend Oreille, a study was proposed to evaluate the benefits of a higher winter elevation, thus providing more spawning gravel for kokanee. This project was designed to collect and compile baseline information on the kokanee population and potential spawning gravel in Lake Pend Oreille that can be used to help evaluate the effectiveness of future changes in lake level management. We estimated the area of suitable quality spawning gravel at the current winter elevation (625.1 m) and at the proposed winter elevation (626.7 m). Gravels beneath the current winter elevation were generally characterized by a high percentage of fine sediments and a high degree of embeddedness. Of the total gravel available below the proposed elevation of 626.7 m, only 15% was available at current winter elevations. Kokanee population estimates were made with a midwater trawl and hydroacoustic surveys in August and September. September population estimates were 6,760,000 age O, 380,000 age 1 +, 700,000 age 2 +, 990,000 age 3 +, 760,000 age 4 +, and 70,000 age 5 + kokanee. Hydroacoustic surveys run alongside the trawl indicated that hydroacoustics can effectively estimate abundance of kokanee, with the exception of fry, which are too small to be completely distinguishable from opossum shrimp Mysis relicta. Historic estimates of wild kokanee fry indicate that winter elevations higher than 625 m and a stable elevation throughout the winter are positively correlated with kokanee fry abundance and survival.

  8. [The feasibility of synthetic enhancer substances for preventive nanotherapy].

    PubMed

    Miklya, Ildiko

    2010-09-01

    Nanotechnology, the great promise of the 21st century, may revolutionize also the art of healing. Previously unexpected broadening of diagnostic procedures and methods to deliver specific drugs acting in lower than nanomolecular concentrations right to the target cells may play a crucial role in the rapid development of preventive medicine. In this context, (-)-deprenyl/selegiline, a drug developed 40 years ago and still world-wide used to treat Parkinson's disease, Alzheimer's disease and depression, by enhancing the activity of catecholaminergic neurons in the brain stem via a previously unknown mechanism [catecholaminergic activity enhancer (CAE) effect], is a highly promising experimental tool for further research in this direction. The same fits for (-)-BPAP, the newly developed enhancer substance, 100 times more potent than (-)-deprenyl, which in contrast to the latter is not only an enhancer of the catecholaminergic neurons but also of the serotonergic neurons in the brain stem. Tiny amounts of enhancer substances are closed in liposomes and marked with a specific signal to help identify the exact location of the target cells, through the activation of which the drug exerts its specific enhancer effect. The method also offers an approach to better understand the up-to-the-present unknown mechanism of the enhancer effect. PMID:20962359

  9. Variability of kokanee and rainbow trout food habits, distribution, and population dynamics, in an ultraoligotrophic lake with no manipulative management

    USGS Publications Warehouse

    Buktenica, M.W.; Girdner, S.F.; Larson, G.L.; McIntire, C.D.

    2007-01-01

    Crater Lake is a unique environment to evaluate the ecology of introduced kokanee and rainbow trout because of its otherwise pristine state, low productivity, absence of manipulative management, and lack of lotic systems for fish spawning. Between 1986 and 2004, kokanee displayed a great deal of variation in population demographics with a pattern that reoccurred in about 10 years. We believe that the reoccurring pattern resulted from density dependent growth, and associated changes in reproduction and abundance, driven by prey resource limitation that resulted from low lake productivity exacerbated by prey consumption when kokanee were abundant. Kokanee fed primarily on small-bodied prey from the mid-water column; whereas rainbow trout fed on large-bodied prey from the benthos and lake surface. Cladoceran zooplankton abundance may be regulated by kokanee. And kokanee growth and reproductive success may be influenced by the availability of Daphnia pulicaria, which was absent in zooplankton samples collected annually from 1990 to 1995, and after 1999. Distribution and diel migration of kokanee varied over the duration of the study and appeared to be most closely associated with prey availability, maximization of bioenergetic efficiency, and fish density. Rainbow trout were less abundant than were kokanee and exhibited less variation in population demographics, distribution, and food habits. There is some evidence that the population dynamics of rainbow trout were in-part related to the availability of kokanee as prey. ?? 2007 Springer Science+Business Media B.V.

  10. Anti-matter propulsion: feasibility, status, and possible enhancement

    SciTech Connect

    Howe, S.D.

    1985-01-01

    The possible use of advanced propulsion techniques must be considered if the currently envisioned launch date of the Manned Mars Mission were to be delayed until 2020 or later. Within the next 30 years, technological advances may allow such methods as beaming power to the ship, inertial-confinement fusion, or mass-conversion of anti-protons to become feasible. Of the possible methods, the anti-proton (anti p), reaction offers the highest potential, the greastest problems, and the most fascination. An Isp of 5000 s would allow the currently envisioned ship to fly to Mars in 3 months and would require about one million pounds to be assembled in Earth orbit. Anti-protons are currently being produced in the world in amounts of about 10/sup 14/ particles per year. With sufficient effort, almost a mg/yr (6 x 10/sup 20/) could be produced by the early 2000s. Current experiments plan to decelerate and capture about 10/sup 10/ or greater anti-protons in an electrostatic Penning trap. Such traps may provide a source of low energy anti p's for development of better storage mechanisms suitable for propulsion. Recently, proposals have been investigated which would amplify the average energy released per anti p used. The proposals entail using the anti p's to produce inertial confinement fusion of a capsule or to produce negative muons which can catalyze fusion. By increasing the energy released per anti p, the effective specific cost, $/joule, can be reduced to attractive levels. These two proposals and other areas of research can be investigated now and will help in assessing the feasibility of an anti p engine.

  11. Dworshak Kokanee Population and Engrainment Assessment : 2006 Annual Report, March 1, 2006 - February 28, 2007.

    SciTech Connect

    Stark, Eric J.

    2008-12-18

    During this contract, we continued testing underwater strobe lights to determine their effectiveness at repelling kokanee Oncorhynchus nerka away from Dworshak Dam. Strobe light tests were conducted on four nights from April 24-27, 2006, in front of the middle reservoir outlet (RO) 2. The density and distribution of fish, (thought to be mostly kokanee), were monitored with a split-beam echo sounder. We then compared fish counts and densities during nights when the lights were flashing to counts and densities during adjacent nights without the lights on. On two nights, April 25 and 27, 2006, when no lights were present, fish counts near RO 2 averaged 12.4 fish and densities averaged 31.0 fish/ha. When strobe lights were turned on during the nights of April 24 and 26, mean counts dropped to 4.7 fish and densities dropped to 0.5 fish/ha. The decline in counts (62%) and densities (99%) was statistically significant (p = 0.009 and 0.002, respectively). Test results indicated that strobe lights were able to reduce fish densities by at least 50% in front of a discharging reservoir outlet, which would be sufficient to improve sport fish harvest. We also used split-beam hydroacoustics to monitor the kokanee population in Dworshak Reservoir during 2006. Estimated abundance of kokanee increased from the 2005 population estimate. Based on hydroacoustic surveys, we estimated approximately 5,815,000 kokanee (90% CI {+-} 27.6%) in Dworshak Reservoir in August 2006. This included 2,183,000 age-0 (90% CI {+-} 24.2%), 1,509,000 age-1 (90% CI {+-} 29.0%), and 2,124,000 age-2 (90% CI {+-} 27.6%) kokanee. This resulted in a density of age-2 kokanee above the management goal of 30-50 adults/ha. Entrainment sampling was conducted with fixed-site, split-beam hydroacoustics from May through September for a continuous 24 h period when dam operations permitted. The highest fish detection rates from entrainment assessments were found during dawn periods, unlike previous year's results, which

  12. Hungry Horse Dam Fisheries Mitigation; Kokanee Stocking and Monitoring in Flathead Lake, 1995 Annual Report.

    SciTech Connect

    Fredenberg, Wade; Carty, Daniel; Cavigli, Jon

    1996-06-01

    The operation of Hungry Horse Dam on the South Fork-of the Flathead River reduced the reproductive success of kokanee (Oncorhynchus nerka) spawning in the Flathead River. Montana Fish, Wildlife and Parks (MFWP) and the Confederated Salish and Kootenai Tribes (CSKT) authored a mitigation plan to offset those losses. The mitigation goal, stated in the Fisheries Mitigation Plan for Losses Attributed to the Construction and Operation of Hungry Horse Dam, is to: {open_quotes}Replace lost annual production of 100,000 kokanee adults, initially through hatchery production and pen rearing in Flathead Lake, partially replacing lost forage for lake trout (Salvelinus namaycush) in Flathead Lake.{close_quotes}

  13. Lake Roosevelt Fisheries Evaluation Program; Meadow Creek vs. Lake Whatcom Stock Kokanee Salmon Investigations in Lake Roosevelt, 2001 Annual Report.

    SciTech Connect

    McLellan, Holly; Scholz, Allan

    2002-03-01

    Lake Roosevelt has been stocked with Lake Whatcom stock kokanee since 1989 with the primary objective of creating a self-sustaining recreational fishery. Due to low return numbers, it was hypothesized a stock of kokanee, native to the upper Columbia River, might perform better than the coastal Lake Whatcom strain. Kokanee from Meadow Creek, a tributary of Kootenay Lake, British Columbia were selected as an alternative stock. Matched pair releases of Lake Whatcom and Meadow Creek kokanee were made from Sherman Creek Hatchery in late June 2000 and repeated in 2001. Stock performance between Lake Whatcom and Meadow Creek kokanee was evaluated using three performance measures; (1) the number of returns to Sherman Creek, the primary egg collection facility, (2) the number of returns to other tributaries and (3) the number of returns to the creel. Kokanee were collected during five passes through the reservoir via electrofishing, which included 87 tributary mouths during the fall of 2000 and 2001. Chi-square analysis indicated age two Meadow Creek kokanee returned to Sherman Creek in significantly higher numbers when compared to the Whatcom stock in 2000 ({chi}{sup 2} = 736.6; d.f. = 1; P < 0.01) and 2001 ({chi}{sup 2} = 156.2; d.f. = 1; P < 0.01). Reservoir wide recoveries of age two kokanee had similar results in 2000 ({chi}{sup 2} = 735.3; d.f. = 1; P < 0.01) and 2001 ({chi}{sup 2} = 150.1; d.f. = 1; P < 0.01). Six Lake Whatcom and seven Meadow Creek three year olds were collected in 2001. The sample size of three year olds was too small for statistical analysis. No kokanee were collected during creel surveys in 2000, and two (age three kokanee) were collected in 2001. Neither of the hatchery kokanee collected were coded wire tagged, therefore stock could not be distinguished. After two years of monitoring, neither Meadow Creek or Lake Whatcom kokanee appear to be capable of providing a run of three-year-old spawners to sustain stocking efforts. The small number of

  14. Feasibility study of enhanced oil recovery for fields in decline. Export trade information (Final)

    SciTech Connect

    Not Available

    1991-08-01

    The report, generated by Scientific Software-Intercomp, Inc. for Yacimientos Petroliferos Fiscales Bolivianos, documents the results of a feasibility study which addressed the viability of developing petroleum areas in Bolivia. The primary objective of the project was to describe the reservoirs that have been discovered and their reserves, describe which would be the best alternatives for development of these reservoirs, and to determine the best alternatives for development of all the reserves together. The report, volume 4 of 4, concerns the feasibility of enhancing the oil or condensate recovery from a chosen group of fields (Yapacani, Humberto Suarez Roca, Vibora, La Pena, San Roque, and Camiri).

  15. Kokanee Stock Status and Contribution of Cabinet Gorge Hatchery, Lake Pend Oreille, Idaho, 1985 Annual Progress Report.

    SciTech Connect

    Bowles, Edward C.

    1986-07-01

    Mid-water trawling techniques were used during September to estimate kokanee population abundance, structure and survival. Abundance in 1985 was estimated at 4.5 million fish (198 per hectare), down from over 12 million kokanee in 1974 when the population was first monitored. Hatchery fry production (<6 million annually) has stabilized kokanee abundance since its initial decline in the late 1960s. Wild fry recruitment has remained relatively stable at 1.8 million since 1978; whereas recruitment of hatchery-reared fry has ranged from 0.09 to 1.98 million. The 1985 creel survey indicated that kokanee harvest rates remain low, with approximately one kokanee harvested per hour of effort from April to August. Catch rates were as high as 3.5 fish per hour during the mid-1960s. The zooplankton community was monitored with periodic plankton tows. Zooplankton composition in 1985 was similar to previous years and appears to have stabilized following the introduction of mysids, with peak cladoceran production occurring several weeks after peak kokanee emergence. Delayed release of hatchery fry resulted in higher survival of hatchery (7.3%) than wild (0.43%) kokanee fry. Other release strategies will be tested as more fry become available.

  16. Feasibility of Single Molecule DNA Sequencing using Surface-Enhanced Raman Scattering

    SciTech Connect

    Talley, C E; Reboredo, F; Chan, J; Lane, S M

    2006-02-03

    We have used a combined theoretical and experimental approach in order to assess the feasibility of using surface-enhanced Raman scattering (SERS) for DNA sequencing at the single molecule level. We have developed a numerical tool capable of calculating the E-field and resulting SERS enhancement factors for metallic structures of arbitrary size and shape. Measurements of the additional SERS enhancement by combining SERS with coherent antistokes Raman scattering (CARS) show that only modest increases in the signal are achievable due to thermal damage at higher laser powers. Finally, measurements of the SERS enhancement from nanoparticles coated with an insulating layer show that the SERS enhancement is decreased by as much as two orders of magnitude when the molecule is not in contact with the metal surface.

  17. Kokanee Stock Status and Contribution of Cabinet Gorge Hatchery, Lake Pend Oreille, Idaho, Final Report.

    SciTech Connect

    Paragamian, Vaugh L.

    1994-07-01

    Lake Pend Oreille once provided the most popular kokanee Oncorhynchus nerka fishery in northern Idaho. A dramatic decline in the population occurred from the mid-1960s to 1970s. Restoration efforts included construction of the Cabinet Gorge Fish Hatchery to supplement the wild population and restore the fishery. In this study, hatchery-reared age 0 kokanee were stocked into Lake Pend Oreille from 1986 through 1992. Seven experimental stocking strategies for kokanee were tested using five locations and two time periods (early May through early June or late July). In 1985, the age 3 and older kokanee totaled about 0.35 million, but rose to 0.78 million in 1986, was stable, was then followed by a decline in 1990 to 0.53 million, then improved to 1.75 million in 1992. Much of the annual variation in total numbers of kokanee, ranging from 4.5 million to 10.2 million, was due to hatchery stockings of age 0 fish. Standing stocks of kokanee remained stable and ranged from 8 to 10 kg/hectare de spite dramatic changes in density due to age 0 fish. Prior to this study (1985), standing stocks were substantially higher (mean = 13.6 kg/hectare), indicating that the population may be operating below carrying capacity. The authors found survival of age 0 hatchery kokanee by each release season to range from 3% in 1986 to 39% in 1992, while the mean from 1987 through 1992 was 23%. They found significant (P=0.05) differences in survival between years, but they could not detect differences between stocking locations (P>0.71). Their analysis of survival between time (early vs late) and location was weak and inconclusive because after 1989 they had fewer fish to stock and could not repeat testing of some release strategies. They believe some of the variation in survival between release groups each year was due to the length of time between release in the lake and trawling.

  18. Text-Messaging-Enhanced HIV Intervention for African American Adolescents: A Feasibility Study

    PubMed Central

    Cornelius, Judith B.; Dmochowski, Jacek; Boyer, Cherrie; St Lawrence, Janet; Lightfoot, Marguerita; Moore, Michael

    2013-01-01

    We examined the feasibility and acceptability of an HIV prevention intervention for African American adolescents delivered via mobile cell phones and looked at intervention-related changes in beliefs and sexual behaviors. We used a longitudinal one-group comparison design with data collected at three points. Forty adolescents, 13–18 years old, participated in the Becoming a Responsible Teen intervention followed by the delivery of daily multimedia messages for 3 months. The mobile-cell-phone enhanced intervention was feasible and acceptable to the participants. Greater HIV knowledge, improved attitudes toward condoms, and increased perceived HIV risk scores were observed with older adolescents (16–18 years old). Behavior trends showed a decrease in the number of times participants reported engaging in unprotected sexual intercourse over the previous 2 months. Mobile-cell-phone multimedia-text-messaging boosters tested in this study provided preliminary evidence of efficacy of the enhanced HIV prevention intervention for African American youth. PMID:23122907

  19. FEASIBILITY AND SAFETY OF CONTRAST-ENHANCED ULTRASOUND IN THE DISTAL LIMB OF SIX HORSES.

    PubMed

    Seiler, Gabriela S; Campbell, Nigel; Nixon, Britton; Tsuruta, James K; Dayton, Paul A; Jennings, Samuel; Redding, W Rich; Lustgarten, Meghann

    2016-05-01

    Vascular alterations play important roles in many orthopedic diseases such as osteoarthritis, tendonitis, and synovitis in both human and equine athletes. Understanding these alterations could enhance diagnosis, prognosis, and treatment. Contrast-enhanced ultrasound (CEUS) could be a valuable method for evaluation of blood flow and perfusion of these processes in the equine distal limb, however no reports were found describing feasibility or safety of the technique. The goal of this prospective, experimental study was to describe the feasibility and safety of distal limb CEUS in a sample of six horses. For each horse, CEUS of the distal limb was performed after intravenous injections of 5 and 10 ml, as well as intra-arterial injections of 0.5 and 1 ml contrast medium. Vital parameters were monitored and CEUS images were assessed qualitatively and quantitatively for degree of contrast enhancement. None of the horses had clinically significant changes in their vital parameters after contrast medium injection. One horse had a transient increase in respiratory rate, and several horses had mild increases of systolic blood pressure of short duration after intravenous, but not after intra-arterial injections. Intra-arterial injection was possible in all horses and resulted in significantly improved contrast enhancement both quantitatively (P = 0.027) and qualitatively (P = 0.019). Findings from this study indicated that CEUS is a feasible and safe diagnostic test for evaluation of the equine distal limb. Future studies are needed to assess the clinical utility of this test for horses with musculoskeletal diseases. PMID:26765518

  20. Effects of the Operation of Hungry Horse Dam on the Kokanee Fishery in the Flathead River System, 1983 Annual Progress Report.

    SciTech Connect

    Fraley, John J.

    1983-11-01

    This study was undertaken to assess the effects of the operation of Hungry Horse Dam on the kokanee fishery in the Flathead River system. This annual report covers the 1982-1983 field season concerning the effects of Hungry Horse operations on kokanee abundance, migration, spawning, egg incubation and fry emergence in the Flathead River system. This report also addresses the expected recovery of the mainstem kokanee population under the flow regime recommended by the Department of Fish, Wildlife and Parks in 1982.

  1. Dworshak Dam Impacts Assessment and Fisheries Investigation: Kokanee Depth Distribution in Dworshak Reservoir and Implications Toward Minimizing Entrainment, 1994 Annual Report.

    SciTech Connect

    Maiolie, Melo; Elam, Steve

    1996-10-01

    The authors measured the day and night depth distribution of kokanee Oncorhynchus nerka kennerlyi directly upstream of Dworshak Dam from October 1993 to December 1994 using split-beam hydroacoustics. At night most kokanee (70%) were distributed in a diffuse layer about 10 m thick. The depth of the layer varied with the season and ranged from 30 to 40 m deep during winter and from 15 to 25 m deep during summer. Nighttime depth of the kokanee layer during summer roughly corresponded to a zone where water temperatures ranged from 7 C to 12 C. Daytime kokanee distribution was much different with kokanee located in dense schools. Most kokanee (70%) were found in a 5--15 m thick layer during summer. Daytime depth distribution was also shallowest during fall and deepest during winter. Dworshak Dam has structures which can be used for selective water withdrawal and can function in depth ranges that will avoid the kokanee layer. Temperature constraints limit the use of selective withdrawal during the spring, summer, and fall, but in the winter, water is nearly isothermal and the full range of selector gate depths may be utilized. From October 1993 to February 1994, selector gates were positioned to withdraw water from above the kokanee layer. The discharge pattern also changed with more water being released during May and July, and less water being released during fall and winter. A combination of these two changes is thought to have increased kokanee densities to a record high of 69 adults/ha.

  2. Dworshak Kokanee Population and Entrainment Assessment 2005-2006 Annual Report.

    SciTech Connect

    Stark, Eric J.

    2008-11-06

    During this contract, we continued testing underwater strobe lights to determine their effectiveness at repelling kokanee Oncorhynchus nerka away from Dworshak Dam. We tested one set of nine strobe lights flashing at a rate of 360 flashes/min in front of turbine 3 while operating at higher discharges than previously tested. The density and distribution of fish, (thought to be mostly kokanee), were monitored with a split-beam echo sounder. We then compared fish counts and densities during nights when the lights were flashing to counts and densities during adjacent nights without the lights on. On five nights between January 31 and February 28, 2006, when no lights were present, fish counts near turbine 3 averaged eight fish and densities averaged 91 fish/ha. When strobe lights were turned on during five adjacent nights during the same period, mean counts dropped to four fish and densities dropped to 35 fish/ha. The decline in counts (49%) was not statistically significant (p = 0.182), but decline in densities (62%) was significant (p = 0.049). There appeared to be no tendency for fish to habituate to the lights during the night. Test results indicated that strobe lights were able to reduce fish densities by at least 50% in front of turbines operating at higher discharges, which would be sufficient to improve sportfish harvest. We also used split-beam hydroacoustics to monitor the kokanee population in Dworshak Reservoir during 2005. Estimated abundance of kokanee decreased from the 2004 population estimate. Based on hydroacoustic surveys, we estimated 3,011,626 kokanee (90% CI {+-} 15.2%) in Dworshak Reservoir, July 2005. This included 2,135,986 age-0 (90% CI {+-} 15.9%), 769,175 age-1 (90% CI {+-} 16.0%), and 107,465 age-2 (90% CI {+-} 15.2%). Poor survival of kokanee from age-1 to age-2 continued to keep age-2 densities below the management goal of 30-50 adults/ha. Entrainment sampling was conducted with fixed-site split-beam hydroacoustics a minimum of two days

  3. Impacts of Water Level Fluctuations on Kokanee Reproduction in Flathead Lake, 1985 Annual Report.

    SciTech Connect

    Beattie, Will; Fraley, John J.; Decker-Hess, Janet

    1986-06-01

    This study has investigated the effects of the operation of Kerr Dam on the reproductive success of kokanee that spawn along the shores of Flathead Lake. We have estimated the spawning escapement to the lakeshore, characterized spawning habitat, monitored egg and alevin survival in redds, and related survival to length of redd exposure due to lake drawdown. Groundwater discharge apparently attracts kokanee to spawning sites along the lakeshore and is responsible for prolonging egg survival in redds above minimum pool. We have quantified and described the effect of lake drawdown on groundwater flux in spawning areas. This report defines optimal lakeshore spawning habitat and discusses eqg and alevin survival both in and below the varial zone.

  4. Lake Roosevelt Fisheries Evaluation Program; Meadow Creek vs. Lake Whatcom Stock Kokanee Salmon Investigations in Lake Roosevelt, Annual Report 2002.

    SciTech Connect

    McLellan, Holly

    2003-03-01

    Lake Whatcom, Washington kokanee have been stocked in Lake Roosevelt since 1987 with the primary objective of creating a self-sustaining fishery. Success has been limited by low recruitment to the fishery, low adult returns to hatcheries, and a skewed sex ratio. It was hypothesized that a stock native to the upper Columbia River might perform better than the coastal Lake Whatcom stock. Kokanee from Meadow Creek, a tributary of Kootenay Lake, British Columbia were selected as an alternative stock. Post smolts from each stock were released from Sherman Creek Hatchery in late June 2000 and repeated in 2001. Stock performance was evaluated using three measures; (1) number of returns to Sherman Creek, the primary egg collection facility, (2) the number of returns to 86 tributaries sampled and, (3) the number of returns to the creel. In two repeated experiments, neither Meadow Creek or Lake Whatcom kokanee appeared to be capable of providing a run of three-year old spawners to sustain stocking efforts. Less than 10 three-years olds from either stock were collected during the study period. Chi-square analysis indicated age two Meadow Creek kokanee returned to Sherman Creek and to other tributaries in significantly higher numbers when compared to the Lake Whatcom stock in both 2000 and 2001. However, preliminary data from the Spokane Tribe of Indians indicated that a large number of both stocks were precocial before they were stocked. The small number of hatchery three-year olds collected indicated that the current hatchery rearing and stocking methods will continue to produce a limited jacking run largely composed of precocious males and a small number of three-year olds. No kokanee from the study were collected during standard lake wide creel surveys. Supplemental creel data, including fishing derbies, test fisheries, and angler diaries, indicated anglers harvested two-year-old hatchery kokanee a month after release. The majority of the two-year old kokanee harvested

  5. Cognitive Enhancement Therapy in Substance Misusing Schizophrenia: Results of an 18-Month Feasibility Trial

    PubMed Central

    Eack, Shaun M.; Hogarty, Susan S.; Greenwald, Deborah P.; Litschge, Maralee Y.; McKnight, Summer A. F.; Bangalore, Srihari S.; Pogue-Geile, Michael F.; Keshavan, Matcheri S.; Cornelius, Jack R.

    2014-01-01

    Substance use is a frequent problem in schizophrenia, and although many substance misusing patients with the disorder also experience considerable cognitive impairments, such individuals have been routinely excluded from clinical trials of cognitive remediation that could support their functional and addiction recovery. This study conducted a small-scale feasibility trial of Cognitive Enhancement Therapy (CET) in substance misusing schizophrenia patients to assess the feasibility and efficacy of implementing comprehensive neurocognitive and social-cognitive remediation in this population. A total of 31 schizophrenia outpatients meeting addiction severity criteria for alcohol and/or cannabis use were randomized to 18 months of CET or usual care. Feasibility findings indicated high degrees of satisfaction with CET, but also presented significant challenges in the recruitment and retention of substance misusing patients, with high levels of attrition (50%) over the study period, primarily due to positive symptom exacerbation. Intent-to-treat efficacy analyses showed large and significant improvements in neurocognition (d = .86), social cognition (d = 1.13), and social adjustment (d = .92) favoring CET. Further, individuals treated with CET were more likely to reduce alcohol use (67% vs. 25%) during treatment (p = .021). These results suggest that once engaged and stabilized, CET is a feasible and potentially effective treatment for cognitive impairments in patients with schizophrenia who misuse alcohol and/or cannabis. Substance misusing patients who are able to engage in treatment may be able to benefit from cognitive remediation, and the treatment of cognitive impairments may help improve substance use outcomes among this underserved population. PMID:25510926

  6. Cognitive Enhancement Therapy in substance misusing schizophrenia: results of an 18-month feasibility trial.

    PubMed

    Eack, Shaun M; Hogarty, Susan S; Greenwald, Deborah P; Litschge, Maralee Y; McKnight, Summer A F; Bangalore, Srihari S; Pogue-Geile, Michael F; Keshavan, Matcheri S; Cornelius, Jack R

    2015-02-01

    Substance use is a frequent problem in schizophrenia, and although many substance misusing patients with the disorder also experience considerable cognitive impairments, such individuals have been routinely excluded from clinical trials of cognitive remediation that could support their functional and addiction recoveries. This study conducted a small-scale feasibility trial of Cognitive Enhancement Therapy (CET) in substance misusing schizophrenia patients to assess the feasibility and efficacy of implementing comprehensive neurocognitive and social-cognitive remediation in this population. A total of 31 schizophrenia outpatients meeting addiction severity criteria for alcohol and/or cannabis use were randomized to 18months of CET or usual care. Feasibility findings indicated high degrees of satisfaction with CET, but also presented significant challenges in the recruitment and retention of substance misusing patients, with high levels of attrition (50%) over the study period, primarily due to positive symptom exacerbation. Intent-to-treat efficacy analyses showed large and significant improvements in neurocognition (d=.86), social cognition (d=1.13), and social adjustment (d=.92) favoring CET. Further, individuals treated with CET were more likely to reduce alcohol use (67% in CET vs. 25% in usual care) during treatment (p=.021). These results suggest that once engaged and stabilized, CET is a feasible and potentially effective treatment for cognitive impairments in patients with schizophrenia who misuse alcohol and/or cannabis. Substance misusing patients who are able to engage in treatment may be able to benefit from cognitive remediation, and the treatment of cognitive impairments may help improve substance use outcomes among this underserved population. PMID:25510926

  7. The Feasibility of Contrast-Enhanced Ultrasound During Uterine Artery Embolization: A Pilot Study

    SciTech Connect

    Dorenberg, Eric J. Jakobsen, Jarl A.; Brabrand, Knut; Hafsahl, Geir; Smith, Hans-Jorgen

    2007-09-15

    Purpose. To evaluate the feasibility of using contrast-enhanced ultrasound (CEUS) during uterine artery embolization (UAE) in order to define the correct end-point of embolization with complete devascularization of all fibroids. Methods. In this prospective study of 10 consecutive women undergoing UAE, CEUS was performed in the angiographic suite during embolization. When the angiographic end-point, defined as the 'pruned-tree' appearance of the uterine arteries was reached, CEUS was performed while the angiographic catheters to both uterine arteries were kept in place. The decision whether or not to continue the embolization was based on the findings at CEUS. The results of CEUS were compared with those of contrast-enhanced magnetic resonance imaging (MRI) 1 day as well as 3 months following UAE. Results. CEUS was successfully performed in all women. In 4 cases injection of particles was continued based on the findings at CEUS despite angiographically complete embolization. CEUS imaging at completion of UAE correlated well with the findings at MRI. Conclusion. The use of CEUS during UAE is feasible and may increase the quality of UAE.

  8. Strobe Light Testing and Kokanee Population Monitoring : Dworshak Dam Impacts Assessment and Fisheries Investigation Project, 87-99 : Annual Progress Report.

    SciTech Connect

    Maiolie, Melo A.; Harryman, Bill; Ament, Willaim J.

    1999-11-01

    We tested the response of kokanee Oncorhynchus nerka to strobe lights. Testing was conducted on wild, free-ranging fish in their natural environment (i.e., the pelagic region of two large Idaho lakes). Split-beam hydroacoustics were used to record the distance kokanee moved away from the lights, as well as the density of kokanee in the area near the lights. In control tests, where strobe lights were lowered into the lake but kept turned off, kokanee remained within a few meters of the lights. Once the lights began flashing, kokanee quickly moved away from the light source. Kokanee moved 20 to 40 m away from the lights in waters with Secchi transparencies from 3 to 5 m. Kokanee densities near the lights were significantly lower (p=0.07 to p=0.00) when the lights were turned on than in control samples with no lights flashing. Flash rates of 300, 360, and 450 flashes/min elicited strong avoidance responses from the fish. Kokanee remained at least 24 m from the lights during our longest test that lasted for 5 h 50 min. We also continued annual monitoring of the kokanee population in Dworshak Reservoir. Spawner counts in four tributary streams that were used as an index of the adult population reached a record low of 144 spawners. No age-1 or age-2 kokanee were caught in 15 trawl hauls used to make population estimates. The population estimate of fry was 65,000 fish, {+-} 76% (90% C.I.). Flooding during the spring of 1996 was responsible for the low kokanee population.

  9. Kokanee Stock Status and Contribution of Cabinet Gorge Hatchery, Lake Pend Oreille, Idaho, 1990 Annual Progress Report.

    SciTech Connect

    Paragamian, Vaughn L.

    1991-03-01

    Rehabilitation of kokanee Oncorhynchus nerka in Lake Pend Oreille met with some success in 1990, but unexpected results have raised new questions. Estimated kokanee abundance during late August of 1990 was about 6.9 million fish. This is a decline of 19% from 1989, a continued decrease since 1988. The decreased population was attributed to low stocking of hatchery fry (7.3 million), lower wild fry survival in 1990 (1.5%), and exceptionally poor survival of fish ages 3+ and 4+. Average survival of the older fish was only 11% in 1990 compared to 72% in prior years. Compensatory survival was noted for kokanee ages 1+ and 2+, with an average of 81% in 1990 compared to 44% in 1989. Hatchery fry comprised 47% of the total kokanee fry recruitment in 1990 (80% of fry biomass). This contribution ranked third behind 1988 and 1989 since hatchery supplementation began in the 1970s. Survival of hatchery fry was 20%, the second highest since this investigation began. Findings of 1990 indicate a more comprehensive approach to managing kokanee must take into account predator stockings and predator/prey interaction. An unexpected low adult escapement was responsible for an egg-take of only 5.6 million eggs in 1990, 58% of the previous year, which will limit experimental stocking in 1991. Modification of the fish ladder at the Cabinet Gorge Fish Hatchery to improve adult escapement is strongly recommended to increase egg-take. 27 refs., 28 figs., 6 tabs.

  10. Lake Roosevelt Fisheries Evaluation Program : Lake Whatcom Kokanee Salmon (Oncorhynchus nerka kennerlyi) : Investigations in Lake Roosevelt Annual Report 1999-2000.

    SciTech Connect

    McLellan, Holly J.; Scholz, Allan T.; McLellan, Jason G.; Tilson, Mary Beth

    2001-07-01

    Lake Whatcom stock kokanee have been planted in Lake Roosevelt since 1988 with the primary goal of establishing a self-sustaining fishery. Returns of hatchery kokanee to egg collection facilities and recruitment to the creel have been minimal. Therefore, four experiments were conducted to determine the most appropriate release strategy that would increase kokanee returns. The first experiment compared morpholine and non-morpholine imprinted kokanee return rates, the second experiment compared early and middle run Whatcom kokanee, the third experiment compared early and late release dates, and the fourth experiment compared three net pen release strategies: Sherman Creek hatchery vs. Sherman Creek net pens, Colville River net pens vs. Sherman Creek net pens, and upper vs. lower reservoir net pen releases. Each experiment was tested in three ways: (1) returns to Sherman Creek, (2) returns to other tributaries throughout the reservoir, and (3) returns to the creel. Chi-square analysis of hatchery and tributary returns indicated no significant difference between morpholine imprinted and non-imprinted fish, early run fish outperformed middle run fish, early release date outperformed late release fish, and the hatchery outperformed all net pen releases. Hatchery kokanee harvest was estimated at 3,323 fish, which was 33% of the total harvest. Return rates (1998 = 0.52%) of Whatcom kokanee were low indicating an overall low performance that could be caused by high entrainment, predation, and precocity. A kokanee stock native to the upper Columbia, as opposed to the coastal Whatcom stock, may perform better in Lake Roosevelt.

  11. Enhanced Flight Vision Systems Operational Feasibility Study Using Radar and Infrared Sensors

    NASA Technical Reports Server (NTRS)

    Etherington, Timothy J.; Kramer, Lynda J.; Severance, Kurt; Bailey, Randall E.; Williams, Steven P.; Harrison, Stephanie J.

    2015-01-01

    Approach and landing operations during periods of reduced visibility have plagued aircraft pilots since the beginning of aviation. Although techniques are currently available to mitigate some of the visibility conditions, these operations are still ultimately limited by the pilot's ability to "see" required visual landing references (e.g., markings and/or lights of threshold and touchdown zone) and require significant and costly ground infrastructure. Certified Enhanced Flight Vision Systems (EFVS) have shown promise to lift the obscuration veil. They allow the pilot to operate with enhanced vision, in lieu of natural vision, in the visual segment to enable equivalent visual operations (EVO). An aviation standards document was developed with industry and government consensus for using an EFVS for approach, landing, and rollout to a safe taxi speed in visibilities as low as 300 feet runway visual range (RVR). These new standards establish performance, integrity, availability, and safety requirements to operate in this regime without reliance on a pilot's or flight crew's natural vision by use of a fail-operational EFVS. A pilot-in-the-loop high-fidelity motion simulation study was conducted at NASA Langley Research Center to evaluate the operational feasibility, pilot workload, and pilot acceptability of conducting straight-in instrument approaches with published vertical guidance to landing, touchdown, and rollout to a safe taxi speed in visibility as low as 300 feet RVR by use of vision system technologies on a head-up display (HUD) without need or reliance on natural vision. Twelve crews flew various landing and departure scenarios in 1800, 1000, 700, and 300 RVR. This paper details the non-normal results of the study including objective and subjective measures of performance and acceptability. The study validated the operational feasibility of approach and departure operations and success was independent of visibility conditions. Failures were handled within the

  12. Kokanee Stock Status and Contribution of Cabinet Gorge Hatchery, Lake Pend Oreille, Idaho, 1991 Annual Progress Report.

    SciTech Connect

    Paragamian, Vaughn L.

    1991-01-01

    Initially, rehabilitation of kokanee Oncorhynchus nerka met with apparent success reaching a peak abundance of 10.2 million fishTl988. However, a decline of 47% followed from 1988 through 1991 to 5.4 million fish. The decreased population was attributed to poor recruitment of wild fish, poor egg take, thus, low stocking of hatchery fry (7.3 million in 1990 and 5.0 million in 1991 compared to about 13.0 million in 1981), and poor survival of fish ages 3 and 4 (average survival of the older fish was only 35% in 1990 compared to 72% in prior years but it was 68% in 1991). In addition, standing stocks of kokanee have remained relatively stable (x = 8.6 kg/hectare) since 1986 despite the dramatic changes in density. Prior to this study (1985) standing stocks were substantially higher (x = 13.6 kg/hectare). The kokanee population is probably operating below carrying capacity. Hatchery fry comprised 59% of the total kokanee recruitment in 1991 (93% of fry biomass). This contribution of 1.06 million fry ranked fifth behind 1988 (3.74 million), 1989 (2.25 million), 1982 (1.89 million), and 1990 (1.56 million) since hatchery supplementation began in the 1970s. Survival of hatchery fry was 21% in 1991, the second highest since this investigation began. Two release strategies were tested in 1991 of which the best survival was recorded for the Sullivan Springs release at 23% while the early Clark Fork River release continued to have lowest survival at 18%. Survival of hatchery reared kokanee fry is still below the goal of 30% and it appears that this goal may not be attainable most years. Statistical analysis between number of days from fry release to recapture day and fry survival did not reveal a relationship (P = 0.43). Survival of fry from late releases is higher (P = 0.05) than early releases but no difference (P L 0.71) was detected between stocking locations. Good survival of fry from the Sullivan Springs releases was attributed to large size of kokanee fry (55 mm), warm

  13. Estimating the impacts of reservoir elevation changes on kokanee emergence in flaming Gorge Reservoir, Wyoming-Utah

    USGS Publications Warehouse

    Modde, T.; Jeric, R.J.; Hubert, W.A.; Gipson, R.D.

    1997-01-01

    Flaming Gorge Reservoir, like many western North American reservoirs, is managed to release water during the winter months to allow for water storage associated with melting snow and rain during spring. Decreases in reservoir elevation during winter can cause mortalities of kokanee Oncorhynchus nerka spawned along the shoreline the previous fall. This study compared data on depth distribution of embryos and depth-adjusted survival to estimate the relative survival of emergent kokanee at different depths and the effect of winter drawdown on the proportion of deposited eggs that survive to emergence. Estimates of decreases in kokanee survival to emergence were 8.3% and 38.1% for reservoir elevation reductions of 1.0 m and 5.0 m, respectively.

  14. Sci—Thur AM: YIS - 04: Gold Nanoparticle Enhanced Arc Radiotherapy: A Monte Carlo Feasibility Study

    SciTech Connect

    Koger, B; Kirkby, C

    2014-08-15

    Introduction: The use of gold nanoparticles (GNPs) in radiotherapy has shown promise for therapeutic enhancement. In this study, we explore the feasibility of enhancing radiotherapy with GNPs in an arc-therapy context. We use Monte Carlo simulations to quantify the macroscopic dose-enhancement ratio (DER) and tumour to normal tissue ratio (TNTR) as functions of photon energy over various tumour and body geometries. Methods: GNP-enhanced arc radiotherapy (GEART) was simulated using the PENELOPE Monte Carlo code and penEasy main program. We simulated 360° arc-therapy with monoenergetic photon energies 50 – 1000 keV and several clinical spectra used to treat a spherical tumour containing uniformly distributed GNPs in a cylindrical tissue phantom. Various geometries were used to simulate different tumour sizes and depths. Voxel dose was used to calculate DERs and TNTRs. Inhomogeneity effects were examined through skull dose in brain tumour treatment simulations. Results: Below 100 keV, DERs greater than 2.0 were observed. Compared to 6 MV, tumour dose at low energies was more conformai, with lower normal tissue dose and higher TNTRs. Both the DER and TNTR increased with increasing cylinder radius and decreasing tumour radius. The inclusion of bone showed excellent tumour conformality at low energies, though with an increase in skull dose (40% of tumour dose with 100 keV compared to 25% with 6 MV). Conclusions: Even in the presence of inhomogeneities, our results show promise for the treatment of deep-seated tumours with low-energy GEART, with greater tumour dose conformality and lower normal tissue dose than 6 MV.

  15. Enhanced phyto-extraction not a feasible option to clean up uranium contaminated soil

    SciTech Connect

    Vandenhove, Hildegarde; Duquene, Lise; Wannijn, Jean; Filip, Tack; Baeten, Joke

    2007-07-01

    Available in abstract form only. Full text of publication follows: A greenhouse experiment was set up to evaluate the potential of enhanced phyto-extraction to clean up U contaminated soils. One soil had a naturally high U concentration and the other soil was impacted by effluents from the former radium extraction industry. Enhancement of U solubility and uptake by plants (ryegrass and Indian mustard) was monitored after addition of 5 chemical amendments (5 mmol kg{sup -1} soil dry weight): citric acid, ammonium citrate-citric acid mixture, oxalic acid, EDDS and NTA. Uranium solubilization and uptake were highly influenced by the amendment applied and soil-plant combinations. Citric acid was most effective in increasing U solubility (up to 18-fold increase). Citric acid and the ammonium citrate-citric acid mixture were most effective in increasing U uptake by ryegrass (up to 6-fold). For Indian mustard, EDDS and citric acid were most effective (up to 9- fold). In the optimal scenario only 0.16 % of the total uranium present in the soil could be extracted with one harvest and it would take more than 200 years to reduce the initial uranium content with 10 %. Based on these results, we must conclude that phyto-extraction is not a feasible technique to decrease the uranium concentration of historically contaminated soils. (authors)

  16. Lake Roosevelt Fisheries Evaluation Program : Meadow Creek vs. Lake Whatcom Stock Kokanee Salmon Investigations in Lake Roosevelt Annual Report 2000-2001.

    SciTech Connect

    McLellan, Holly J.; Scholz, Allan T.

    2001-07-01

    Lake Roosevelt has been stocked with Whatcom stock kokanee since 1989 to mitigate for anadromous salmon losses caused by the construction of Grand Coulee Dam. The primary objective of the hatchery plantings was to create a self-sustaining recreational fishery. Due to low return numbers, it was hypothesized a native stock of kokanee might perform better than the coastal Whatcom strain. Therefore, kokanee from Meadow Creek, a tributary of Kootenay Lake, British Columbia were selected as an alternative stock. Matched pair releases of Whatcom stock and Meadow Creek kokanee were made from Sherman Creek in late June 2000. Stock performance between Lake Whatcom and Meadow Creek kokanee was evaluated through three performance measures (1) returns to Sherman Creek, the primary egg collection facility, (2) returns to other tributaries, indicating availability for angler harvest, and (3) returns to the creel. A secondary objective was to evaluate the numbers collected at downstream fish passage facilities. Age 2 kokanee were collected during five passes through the reservoir, which included 89 tributaries between August 17th and November 7th, 2000. Sherman Creek was sampled once a week because it was the primary egg collection location. A total of 2,789 age 2 kokanee were collected, in which 2,658 (95%) were collected at Sherman Creek. Chi-square analysis indicated the Meadow Creek kokanee returned to Sherman Creek in significantly higher numbers compared to the Whatcom stock ({chi}{sup 2} = 734.4; P < 0.01). Reservoir wide recoveries indicated similar results ({chi}{sup 2} = 733.1; P < 0.01). No age 2 kokanee were collected during creel surveys. Age 3 kokanee are expected to recruit to the creel in 2001. No age 2 kokanee were collected at the fish passage facilities due to a 170 mm size restriction at the fish passage centers. Age 3 kokanee are expected to be collected at the fish passage centers during 2001. Stock performance cannot be properly evaluated until 2001, when

  17. Effects of the Operation of Kerr and Hungry Horse Dams on the Kokanee Fishery in the Flathead River System, 1979-1985 Final Research Report.

    SciTech Connect

    Clancy, Patrick

    1986-05-01

    This study was undertaken to assess the effects of the operation of Hungry Horse Dam on the kokanee fishery in the Flathead River system. Studies concerning operation of the dam on the Flathead River aquatic biota began in 1979 and continued to 1982 under Bureau of Reclamation funding. These studies resulted in flow recommendations for the aquatic biota in the main stem Flathead River, below the influence of Hungry Horse Dam on the South Fork. Studies concerned specifically with kokanee salmon have continued under Bonneville Power Administration funding since 1982. This completion report covers the entire study period (September 1979 to June 1985). Major results of this study were: (1) development and refinement of methods to assess hydropower impacts on spawning and incubation success of kokanee; (2) development of a model to predict kokanee year class strength from Flathead River flows; and (3) implementation of flows favorable for successful kokanee reproduction. A monitoring program has been developed which will assess the recovery of the kokanee population as it proceeds, and to recommend management strategies to maintain management goals for the kokanee fishery in the river system.

  18. A feasibility study of a microgravity enhancement system for Space Station Freedom

    NASA Technical Reports Server (NTRS)

    Diamond, Preston S.; Tolson, Robert H.

    1993-01-01

    The current low frequency microgravity requirements for Space Station Freedom (SSF) call for a level of less than 1 micro-g over 50 percent of all the laboratory racks for continuous periods of 30 days for at least 180 days per year. While this requirement is attainable for some of the laboratory modules for the Permanently Manned Configuration (PMC), it can not be met for the Man-Tended Configuration (MTC). In addition, many experiments would prefer even lower acceleration levels. To improve the microgravity environment, the Microgravity Enhancement System (MESYS) will apply a continuous thrust to SSF, to negate the disturbing gravity gradient and drag forces. The MESYS consists of a sensor, throttle-able thrusters and a control system. Both a proof mass system and accelerometer were evaluated for use as the sensor. The net result of the MESYS will be to shift the microgravity contours from the center of mass to a chosen location. Results indicate the MESYS is not feasible for MTC since it will require 5,073 kg of hydrazine fuel and 7,660 watts of power for 30 days of operation during average atmospheric conditions. For PMC, the MESYS is much more practical since only 4,008 kg of fuel and 5,640 watts of power are required.

  19. Enhanced propionic acid degradation (EPAD) system: proof of principle and feasibility.

    PubMed

    Ma, Jingxing; Carballa, Marta; Van De Caveye, Pieter; Verstraete, Willy

    2009-07-01

    Full-scale anaerobic single-phase digesters can be confronted with process instabilities, which often result in the accumulation of propionic acid (HPr). As a solution, an enhanced propionic acid degradation (EPAD) system has been conceptually designed and experimentally tested at lab-scale. The system consisted of two components: a liquid/solid separator containing a microfiltration membrane and an up-flow anaerobic sludge bed (UASB) reactor specialized in HPr degradation. Two lab-scale continuous stirred tank reactors (CSTR) were used, i.e. the CSTR(control) and the CSTR(treatment). Firstly, the CSTRs were stressed by organic overloading to obtain high HPr levels. During the recovery period, besides stop feeding, no actions were taken to decrease the residual HPr concentration in the CSTR(control), while the CSTR(treatment) was connected to EPAD system in order to accelerate its recovery. By the end of the experiment, the CSTR(treatment) completely recovered from HPr accumulation, while no significant decrease of the HPr level in the CSTR(control) was observed. Based on the experimental results, the up-scaling of EPAD system was evaluated and it would only account for about 2% of the volume of the full-scale digester, thus suggesting that the implementation of a mobile EPAD system in full-scale practice should be feasible. PMID:19515396

  20. Feasibility and Usefulness of Intra-Cavitary Contrast-Enhanced Ultrasound in Percutaneous Nephrostomy.

    PubMed

    Cui, Xin-Wu; Ignee, Andre; Maros, Tiberius; Straub, Bernd; Wen, Jian-Guo; Dietrich, Christoph F

    2016-09-01

    The aim of this study was to evaluate the feasibility and utility of intra-cavitary contrast enhanced ultrasound (ICCEUS) in guiding percutaneous nephrostomy (PCN) and assessing complications. Forty-five ultrasound-guided PCNs were performed in 35 patients with hydronephrosis resulting from urinary tract obstruction. Ultrasound contrast agent (0.1 mL diluted in 20-30 mL saline) was injected through the puncture needle and the drainage tube to precisely locate the device and obstruction, with the fluoroscopy results considered the gold standard. ICCEUS was performed again the next day to assess complications. All 45 PCNs were successfully performed under the guidance of ultrasound. With ICCEUS, we could confirm the correct insertion of needle and catheter and locate the obstruction in all 35 patients, with fluoroscopic results as the gold standard. Catheter dislodgement was diagnosed by administration of ultrasound contrast agent in 5 patients. Hematoma (1 patient) and urine leakage (1 patient) were also observed. With the advantages of lack of exposure to radiation, performance in real time and bedside availability, ICCEUS has the potential to become a new modality to guide PCN and assess catheter-related complications. PMID:27262520

  1. Composition and location of simulated lake-shore redds influence incubation success in kokanee, Oncorhynchus nerka

    USGS Publications Warehouse

    Fincel, M.J.; Chipps, S.R.; Bennett, D.H.

    2009-01-01

    Methods for improving spawning habitat for lakeshore spawning kokanee, Oncorhynchus nerka (Walbaum), were explored by quantifying incubation success of embryos exposed to three substrate treatments in Lake Pend Oreille, Idaho, USA. Substrate treatments included no modification that used existing gravels in the lake (EXISTING), a cleaned substrate treatment where existing gravels were sifted in the water column to remove silt (CLEANED) and the addition of new, silt-free gravel (ADDED). Incubation success was evaluated using Whitlock-Vibert incubation boxes buried within each substrate treatment that contained recently fertilised embryos. Upon retrieval, live and dead sac fry and eyed eggs were enumerated to determine incubation success (sac fry and eyed eggs ?? 100/number of fertilised embryos). Incubation success varied significantly among locations and redd treatments. In general, incubation success among ADDED redds (0.0-13.0%) was significantly lower than that for EXISTING (1.4-61.0%) and CLEANED (0.4-62.5%) redds. Adding new gravel to spawning areas changed the morphometry of the gravel-water interface and probably exposed embryos to disturbance from wave action and reduced embryo survival. Moreover, efforts to improve spawning habitat for lakeshore spawning kokanee should consider water depth and location (e.g. protected shorelines) as important variables. Adding clean gravel to existing spawning areas may provide little benefit if water depth or lake-bottom morphometry are altered. ?? 2009 Blackwell Publishing Ltd.

  2. Cavitation-enhanced nonthermal ablation in deep brain targets: feasibility in a large animal model.

    PubMed

    Arvanitis, Costas D; Vykhodtseva, Natalia; Jolesz, Ferenc; Livingstone, Margaret; McDannold, Nathan

    2016-05-01

    OBJECT Transcranial MRI-guided focused ultrasound (TcMRgFUS) is an emerging noninvasive alternative to surgery and radiosurgery that is undergoing testing for tumor ablation and functional neurosurgery. The method is currently limited to central brain targets due to skull heating and other factors. An alternative ablative approach combines very low intensity ultrasound bursts and an intravenously administered microbubble agent to locally destroy the vasculature. The objective of this work was to investigate whether it is feasible to use this approach at deep brain targets near the skull base in nonhuman primates. METHODS In 4 rhesus macaques, targets near the skull base were ablated using a clinical TcMRgFUS system operating at 220 kHz. Low-duty-cycle ultrasound exposures (sonications) were applied for 5 minutes in conjunction with the ultrasound contrast agent Definity, which was administered as a bolus injection or continuous infusion. The acoustic power level was set to be near the inertial cavitation threshold, which was measured using passive monitoring of the acoustic emissions. The resulting tissue effects were investigated with MRI and with histological analysis performed 3 hours to 1 week after sonication. RESULTS Thirteen targets were sonicated in regions next to the optic tract in the 4 animals. Inertial cavitation, indicated by broadband acoustic emissions, occurred at acoustic pressure amplitudes ranging from 340 to 540 kPa. MRI analysis suggested that the lesions had a central region containing red blood cell extravasations that was surrounded by edema. Blood-brain barrier disruption was observed on contrast-enhanced MRI in the lesions and in a surrounding region corresponding to the prefocal area of the FUS system. In histology, lesions consisting of tissue undergoing ischemic necrosis were found in all regions that were sonicated above the inertial cavitation threshold. Tissue damage in prefocal areas was found in several cases, suggesting that in

  3. Investigating the Feasibility of Traveltime Tomography for Monitoring CO2 Enhanced Oil Recovery

    NASA Astrophysics Data System (ADS)

    Barghouty, L. K.; Quan, Y.; Harris, J. M.

    2012-12-01

    CO2 Enhanced Oil Recovery (EOR) is a process for improving the recovery of oil from a reservoir through injection of carbon dioxide. The monitoring CO2 EOR requires an effective method that detects the location of injected CO2 in the reservoir. This project investigates the feasibility of using crosswell seismic tomography to monitor the distribution of injected CO2. Tomography converts seismic traveltime data into seismic velocity models. The effectiveness of seismic tomography as a monitoring method depends on the level of its repeatability, e.g., how accurate the results will be under possible survey challenges such as incomplete datasets and errors in survey geometry. These challenges are found in the seismic data in a field test from west Texas. Using synthetic data comprising pre-injection and post-injection datasets similar to the recorded field datasets, several data processing techniques have been tested to assess the difference between the pre-injection and post-injection velocity models, to determine how data processing affects the time-lapse results. Such tests include limiting the aperture of one or both surveys, eliminating near offset data where traveltime picks are difficult to make, shifting receivers/sources depth coordinates to simulate the survey acquisition errors, and patching (data extrapolation) to correct for missing data. Synthetic results show that near-offset elimination does not notably affect the quality of the time-lapse results while matching pre- and post-injection survey geometries gives better results even for incomplete survey geometries. Patching of incomplete datasets gives reasonable results within certain limits, and having a depth error more than twice the inversion grid size significantly affects the results. Based on synthetic results, repeatability of seismic tomography depends highly on the accuracy of source and receiver coordinates, while repeatability tolerates mismatching pre-injection and post-injection survey

  4. Electrophoretic Particle Guidance Significantly Enhances Olfactory Drug Delivery: A Feasibility Study

    PubMed Central

    Xi, Jinxiang; Si, Xiuhua A.; Gaide, Rachel

    2014-01-01

    Background Intranasal olfactory drug delivery provides a non-invasive method that bypasses the Blood-Brain-Barrier and directly delivers medication to the brain and spinal cord. However, a device designed specifically for olfactory delivery has not yet been found. Methods In this study, a new delivery method was proposed that utilized electrophoretic forces to guide drug particles to the olfactory region. The feasibility of this method was numerically evaluated in both idealized 2-D and anatomically accurate 3-D nose models. The influence of nasal airflow, electrode strength, and drug release position were also studied on the olfactory delivery efficiency. Findings Results showed that by applying electrophoretic forces, the dosage to the olfactory region was significantly enhanced. In both 2-D and 3-D cases, electrophoretic-guided delivery achieved olfactory dosages nearly two orders of magnitude higher than that without electrophoretic forces. Furthermore, releasing drugs into the upper half of the nostril (i.e., partial release) led to olfactory dosages two times higher than releasing drugs over the entire area of the nostril. By combining the advantages of pointed drug release and appropriate electrophoretic guidance, olfactory dosages of more than 90% were observed as compared to the extremely low olfactory dosage (<1%) with conventional inhaler devices. Conclusion Results of this study have important implications in developing personalized olfactory delivery protocols for the treatment of neurological disorders. Moreover, a high sensitivity of olfactory dosage was observed in relation to different pointed release positions, indicating the importance of precise particle guidance for effective olfactory delivery. PMID:24497957

  5. Feasibility and usefulness of using swallow contrast-enhanced ultrasound to diagnose Zenker's diverticulum: preliminary results.

    PubMed

    Cui, Xin-Wu; Ignee, Andre; Baum, Ulrich; Dietrich, Christoph F

    2015-04-01

    Zenker's diverticulum (ZD) may be misdiagnosed on conventional ultrasound as a thyroid nodule or other lesion. A barium esophagram is usually used to confirm the diagnosis; however, this procedure exposes the patient to radiation. The aim of this study was to evaluate the feasibility of using swallow contrast-enhanced ultrasound (swallow-CEUS) to diagnose ZD. Ten consecutive patients with ZD (7 men and 3 women, aged 67 ± 11 y) were included in the study. In 4 patients, ZD was incidentally found on head and neck ultrasound, and in 6 patients, ZD was suspected because of dysphagia. All lesions could be detected on conventional ultrasound before swallow-CEUS. Ten healthy volunteers (8 men and 2 women, aged 60 ± 12 y) were chosen as a control group. Written informed consent was obtained. With the patient in the sitting or upright position, conventional ultrasound was performed first to image the lesion, then the patient was asked to swallow ultrasound contrast agent (UCA) (2-4 drops of SonoVue diluted with about 200 mL of tap water). Transity of the contrast agent in the esophagus was imaged with CEUS. Retention of the UCA in the diverticulum was monitored for at least 3 min. All patients underwent a barium esophagram as the gold standard. Swallow-CEUS revealed that in all patients (100%), the UCA was transported from the pharynx to the esophagus while the patient swallowed. ZD appeared as a pouch-shaped structure at the posterior pharyngo-esophageal junction that retained UCA longer than 3 min. The barium esophagram confirmed the diagnosis of ZD in all patients. For the 10 volunteers, no abnormal structure (retaining UCA) was detected during or after swallowing of UCA. With the advantages of no radiation and bedside availability, swallow-CEUS may become a method of choice in confirmation of the diagnosis of ZD, especially when ZD is suspected on conventional ultrasound. PMID:25701519

  6. Lake Roosevelt Fisheries Monitoring Progam; Thyroid-Induced Chemical Imprinting in Early Life Stages and Assessment of Smoltification in Kokanee Salmon Implications for Operating Lake Roosevelt Kokanee Salmon Hatcheries; 1993 Supplement Report.

    SciTech Connect

    Tilson, Mary Beth; Galloway, Heather; Scholz, Allan T.

    1994-06-01

    In 1991, two hatcheries were built to provide a kokanee salmon and rainbow trout fishery for Lake Roosevelt as partial mitigation for the loss of anadromous salmon and steelhead caused by construction of Grand Coulee Dam. The Sherman Creek Hatchery, located on a tributary of Lake Roosevelt to provide an egg collection and imprinting site, is small with limited rearing capability. The second hatchery was located on the Spokane Indian Reservation because of a spring water source that supplied cold, pure water for incubating and rearing eggs.`The Spokane Tribal Hatchery thus serves as the production facility. Fish reared there are released into Sherman Creek and other tributary streams as 7-9 month old fry. However, to date, returns of adult fish to release sites has been poor. If hatchery reared kokanee imprint to the hatchery water at egg or swim up stages before 3 months of age, they may not be imprinting as 7-9 month old fry at the time of stocking. In addition, if these fish undergo a smolt phase in the reservoir when they are 1.5 years old, they could migrate below Grand Coulee Dam and out of the Lake Roosevelt system. In the present investigation, which is part of the Lake Roosevelt monitoring program to assess hatchery effectiveness, kokanee salmon were tested to determine if they experienced thyroxine-induced chemical imprinting and smoltification similar to anadromous salmonids. Determination of the critical period for olfactory imprinting was determined by exposing kokanee to different synthetic chemicals (morpholine or phenethyl alcohol) at different life stages, and then measuring the ability to discriminate the chemicals as sexually mature adults. Whole body thyroxine content and blood plasma thyroxine concentration was measured to determine if peak thyroid activity coincided with imprinting or other morphological, physiological or behavioral transitions associated with smoltification.

  7. Feasibility of introducing ferromagnetic materials to onboard bulk high-Tc superconductors to enhance the performance of present maglev systems

    NASA Astrophysics Data System (ADS)

    Deng, Zigang; Wang, Jiasu; Zheng, Jun; Zhang, Ya; Wang, Suyu

    2013-02-01

    Performance improvement is a long-term research task for the promotion of practical application of promising high-temperature superconducting (HTS) magnetic levitation (maglev) vehicle technologies. We studied the feasibility to enhance the performance of present HTS Maglev systems by introducing ferromagnetic materials to onboard bulk superconductors. The principle here is to make use of the high magnetic permeability of ferromagnetic materials to alter the flux distribution of the permanent magnet guideway for the enhancement of magnetic field density at the position of the bulk superconductors. Ferromagnetic iron plates were added to the upper surface of bulk superconductors and their geometric and positioning effects on the maglev performance were investigated experimentally. Results show that the guidance performance (stability) was enhanced greatly for a particular setup when compared to the present maglev system which is helpful in the application where large guidance forces are needed such as maglev tracks with high degrees of curves.

  8. Feasibility of Behavioral Weight Loss Treatment Enhanced with Peer Support and Mobile Health Technology for Individuals with Serious Mental Illness.

    PubMed

    Aschbrenner, Kelly A; Naslund, John A; Shevenell, Megan; Mueser, Kim T; Bartels, Stephen J

    2016-09-01

    Effective and scalable lifestyle interventions are needed to address high rates of obesity in people with serious mental illness (SMI). This pilot study evaluated the feasibility of a behavioral weight loss intervention enhanced with peer support and mobile health (mHealth) technology for obese individuals with SMI. The Diabetes Prevention Program Group Lifestyle Balance intervention enhanced with peer support and mHealth technology was implemented in a community mental health setting. Thirteen obese individuals with SMI participated in a pre-post pilot study of the 24-week intervention. Feasibility was assessed by program attendance, and participant satisfaction and suggestions for improving the model. Descriptive changes in weight and fitness were also explored. Overall attendance amounted to approximately half (56 %) of weekly sessions. At 6-month follow-up, 45 % of participants had lost weight, and 45 % showed improved fitness by increasing their walking distance. Participants suggested a number of modifications to increase the relevance of the intervention for people with SMI, including less didactic instruction and more active learning, a simplified dietary component, more in depth technology training, and greater attention to mental health. The principles of standard behavioral weight loss treatment provide a useful starting point for promoting weight loss in people with SMI. However, adaptions to standard weight loss curricula are needed to enhance engagement, participation, and outcomes to respond to the unique challenges of individuals with SMI. PMID:26462674

  9. The Safety and Health Improvement: Enhancing Law Enforcement Departments Study: Feasibility and Findings

    PubMed Central

    Kuehl, Kerry S.; Elliot, Diane L.; Goldberg, Linn; MacKinnon, David P.; Vila, Bryan J.; Smith, Jennifer; Miočević, Milica; O’Rourke, Holly P.; Valente, Matthew J.; DeFrancesco, Carol; Sleigh, Adriana; McGinnis, Wendy

    2014-01-01

    This randomized prospective trial aimed to assess the feasibility and efficacy of a team-based worksite health and safety intervention for law enforcement personnel. Four-hundred and eight subjects were enrolled and half were randomized to meet for weekly, peer-led sessions delivered from a scripted team-based health and safety curriculum. Curriculum addressed: exercise, nutrition, stress, sleep, body weight, injury, and other unhealthy lifestyle behaviors such as smoking and heavy alcohol use. Health and safety questionnaires administered before and after the intervention found significant improvements for increased fruit and vegetable consumption, overall healthy eating, increased sleep quantity and sleep quality, and reduced personal stress. PMID:24847475

  10. Enhancing Resilience Among New Nurses: Feasibility and Efficacy of a Pilot Intervention

    PubMed Central

    Chesak, Sherry S.; Bhagra, Anjali; Schroeder, Darrell R.; Foy, Denise A.; Cutshall, Susanne M.; Sood, Amit

    2015-01-01

    Background Orientation is one of the most stressful times in a registered nurse's career. Little information is available regarding the efficacy of stress management approaches among new nurses. The purpose of this study was to examine outcomes of the implementation of a brief Stress Management and Resiliency Training (SMART) program within a nurse orientation program. Methods In this randomized controlled pilot study, self-reported measures of stress, mindfulness, anxiety, and resilience were measured at baseline and 12 weeks following the intervention. For each group, the mean change from baseline to week 12 was evaluated using the paired t test. The change from baseline was compared between groups using the 2-sample t test. Feasibility of integrating the SMART program into the nurse orientation program was also analyzed. Results Of the 55 participants enrolled, 40 (73%) completed the study. Mindfulness and resilience scores improved in the intervention group and declined in the control group, while stress and anxiety scores decreased in the intervention group and increased in the control group. The between-group change in each outcome, however, was not statistically significant. Conclusions Integrating the SMART program within the nurse orientation program is feasible. While changes between groups were not significant, trends in the results indicate that the program has the potential for efficacy. Future research with larger numbers is indicated with a revised version of the program to increase its effect size. PMID:25829879

  11. Using prize-based incentives to enhance daily interactive voice response (IVR) compliance: A feasibility study

    PubMed Central

    Lindsay, Jan A.; Minard, Charles G.; Hudson, Sonora; Green, Charles E.; Schmitz, Joy M.

    2013-01-01

    This study examined the feasibility of a prize-based contingency-management (CM) approach to encourage interactive voice response (IVR) compliance in a cocaine-treatment study and explored the association between IVR call rate and outcome during a cocaine abstinence-induction trial. Subjects called into the IVR system daily to complete a brief interview assessing cocaine use for past 24 hours. One group earned $1 for each call; the other earned one draw per call from a “prize bowl” with a range of awards. Abstinence was rewarded according to a high-value voucher incentive schedule, which was the same for both groups, and confirmed by thrice-weekly urine testing at clinic visits. Odds of calling were 4.7 times greater (95% CI: 1.23, 17.91) in the prize-CM group than in the fixed dollar CM group. In addition, the percent of IVR calls was significantly associated with abstinence achievement, χ2 (1) = 5.147, p<0.023. The use of prize-based CM to increase the use of IVR is feasible and deserves examination as an innovation for helping participants engage in treatment. PMID:24029622

  12. A feasibility study on HTS SMES applications for power quality enhancement through both software simulations and hardware-based experiments

    NASA Astrophysics Data System (ADS)

    Kim, A. R.; Kim, J. G.; Kim, S.; Park, M.; Yu, I. K.; Seong, K. C.; Watanabe, K.

    2011-11-01

    Superconducting magnetic energy storage (SMES) which promises the efficiency of more than 95% and fast response becomes a competitive energy storage device. Because of its advantages, SMES can provide benefit as a power quality enhancement device to an utility especially in connection with renewable energy sources. In this paper, a software simulation and an experiment aiming for power quality enhancement are reported. The utility was referred to Ulleung Island in Korea which had one wind power generation system. The simulation was performed using power system computer aided design/electromagnetic transient including DC (PSCAD/EMTDC) and power-hardware-in-the-loop simulation (PHILS) was implemented to monitor the operational characteristics of SMES when it was connected to utility. This study provides a highly reliable simulation results, and the feasibility of a SMES application is discussed.

  13. A technology-enabled adherence enhancement system for people with bipolar disorder: results from a feasibility and patient acceptance analysis

    PubMed Central

    Sajatovic, Martha; Davis, Michael S; Cassidy, Kristin A; Nestor, Joseph; Sams, Johnny; Fuentes-Casiano, Edna

    2015-01-01

    Objective As poor medication adherence is common in bipolar disorder (BD), technology-assisted approaches may help to monitor and enhance adherence. This study evaluated preliminary feasibility, patient satisfaction and effects on adherence, BD knowledge, and BD symptoms associated with the use of a multicomponent technology-assisted adherence enhancement system. Methods This prospective study tested the system in five BD patients over a 15-day period. System components included: 1) an automated pill cap with remote monitoring sensor; 2) a multimedia adherence enhancement program; and 3) a treatment incentive program. This study evaluated system usability, patient satisfaction and effects on adherence (Morisky scale), knowledge (treatment knowledge test [TKT]), and symptoms (internal state scale [ISS]). Results Mean age of the sample was 62 years, 4/5 (80%) Caucasian, and 4/5 (80%) single/divorced or widowed. Most participants (4/5, 80%) were on a single BD medication. Participants had BD for an average of 21 years. Challenges included attaching the pill sensor to standard pharmacy bottles for individuals using very large pill containers or those with multiday pill boxes. Three of five (60%) individuals completed the full 15-day period. Usability scores were high overall. Mean Morisky scores improved. Means on all four subscales of the ISS were all in the direction of improvement. On the TKT, there was a 40% increase in mean scores. Conclusion A multicomponent technology-assisted BD adherence enhancement system is feasible. Challenges include accommodating multiple types of pill containers and monitoring multiple drugs simultaneously. The system can also generate adherence information that is potentially useful for treatment planning. PMID:26089652

  14. Detection of magnetically enhanced cancer tumors using SQUID magnetometry: A feasibility study

    NASA Astrophysics Data System (ADS)

    Kenning, G. G.; Rodriguez, R.; Zotev, V. S.; Moslemi, A.; Wilson, S.; Hawel, L.; Byus, C.; Kovach, J. S.

    2005-01-01

    Nanoparticles bound to various biological molecules and pharmacological agents can be administered systemically, to humans without apparent toxicity. This opens an era in the targeting of specific tissues and disease processes for noninvasive imaging and treatment. An important class of particles used predominantly for magnetic resonance imaging is based on iron-oxide ferrites. We performed computer simulations using experimentally determined values for concentrations of superparamagnetic particles achievable in specific tissues of the mouse in vivo and concentrations of particles linked to monoclonal antibodies specific to antigens of two human cancer cell lines in vitro. An instrument to target distance of 12cm, into the body, was selected as relevant to our goal of developing a rapid inexpensive method of scanning the body for occult disease. The simulations demonstrate the potential feasibility of superconducting quantum interference device magnetometry to detect induced magnetic fields in focal concentrations of superparamagnetic particles targeted, in vivo, to sites of disease.

  15. Enhancing Sibling Relationships to Prevent Adolescent Problem Behaviors: Theory, Design and Feasibility of Siblings Are Special

    PubMed Central

    Feinberg, Mark E.; Sakuma, Kari-Lyn; Hostetler, Michelle; McHale, Susan M.

    2012-01-01

    Siblings play a significant but neglected role in family socialization dynamics, and focusing on the sibling relationship is a non-stigmatizing point of entry into the family for prevention programming. Siblings are Special (SAS) was designed as a universal program that targets both sibling relationship and parenting mediating processes in middle childhood to prevent behavior problems in adolescence. We describe the theoretical framework underlying SAS, the SAS curriculum, and the feasibility of the program based on a study of 128 middle-childhood aged sibling dyads. Data on the quality of program implementation, program fidelity, siblings’ engagement, and ratings of impact indicated the SAS program was acceptable to families and schools, that the curriculum could be implemented with high fidelity, that siblings and parents participated at high levels and were highly engaged, and that, from the perspective of group leaders, school administrators and parents, the program had a positive impact on the siblings. PMID:23000632

  16. Feasibility study of ferromagnetic/ferroelectric films for enhanced microwave devices

    NASA Technical Reports Server (NTRS)

    Ijiri, Yumi

    2005-01-01

    This report summarizes exploratory work conducted to assess the feasibility of ferromagnetic/ferroelectric films for next-generation microwave devices. From literature review, it is established that while an increasing number of ferroelectric/ferromagnetic composites are being investigated, a number have transition temperatures that are too low and structures that are not robust enough for low cost, room temperature antenna arrays. On the other hand, several promising systems are identified, including the multiferroic BiFeO3 and a composite system of Ba/SrTiO3 and a related perovskite manganite. It is suggested that when the NASA pulsed laser deposition chamber is fully operational, thin films of these systems be investigated. In preparation for such work, we have reconfirmed several structural features of an existing Ba/SrTiO3 film using the x-ray diffractometer at Oberlin College.

  17. Migration timing of female kokanee salmon Oncorhynchus nerka: diel patterns and effects of maturation state.

    PubMed

    Warren, M A; Morbey, Y E

    2012-09-01

    Diel patterns of migration and migration speed were compared between reproductive timing phenotypes in female kokanee salmon Oncorhynchus nerka. Females of varying degrees of reproductive maturation were captured on their migration route to the Meadow Creek Spawning Channel (British Columbia, Canada), were tagged with passive-integrated transponders (PIT tags) and were subsequently monitored with stationary receivers. Females showed crepuscular migration timing, with approximately equal detections at dawn and dusk. In particular, peaks of movement were associated with the appearance of the sun over the mountains in the east and the disappearance of the sun over the mountains in the west. Over 25 m, migration speed was 1·0 body lengths (measured as fork length; L(F)) s(-1) and did not depend on maturation state. Over 3 km, migration speed was much slower (0·2-0·3 L(F) s(-1)) than over the short distance, with less mature females migrating more slowly than more mature females. Less mature females appeared to be in less of a hurry to reach breeding areas compared with more mature females. PMID:22957867

  18. Cognitive Enhancement Therapy for Adults with Autism Spectrum Disorder: Results of an 18-Month Feasibility Study

    ERIC Educational Resources Information Center

    Eack, Shaun M.; Greenwald, Deborah P.; Hogarty, Susan S.; Bahorik, Amber L.; Litschge, Maralee Y.; Mazefsky, Carla A.; Minshew, Nancy J.

    2013-01-01

    Adults with autism experience significant impairments in social and non-social information processing for which few treatments have been developed. This study conducted an 18-month uncontrolled trial of Cognitive Enhancement Therapy (CET), a comprehensive cognitive rehabilitation intervention, in 14 verbal adults with autism spectrum disorder to…

  19. A Decision Support Framework for Feasibility Analysis of International Space Station (ISS) Research Capability Enhancing Options

    NASA Technical Reports Server (NTRS)

    Ortiz, James N.; Scott,Kelly; Smith, Harold

    2004-01-01

    The assembly and operation of the ISS has generated significant challenges that have ultimately impacted resources available to the program's primary mission: research. To address this, program personnel routinely perform trade-off studies on alternative options to enhance research. The approach, content level of analysis and resulting outputs of these studies vary due to many factors, however, complicating the Program Manager's job of selecting the best option. To address this, the program requested a framework be developed to evaluate multiple research-enhancing options in a thorough, disciplined and repeatable manner, and to identify the best option on the basis of cost, benefit and risk. The resulting framework consisted of a systematic methodology and a decision-support toolset. The framework provides quantifiable and repeatable means for ranking research-enhancing options for the complex and multiple-constraint domain of the space research laboratory. This paper describes the development, verification and validation of this framework and provides observations on its operational use.

  20. Lake Roosevelt Fisheries Monitoring Program; Measurement of Thyroxin Concentration as an Indicator of the Critical Period for Imprinting in the Kokanee Salmon (Orcorhynchus Nerka) Implications for Operating Lake Roosevelt Kokanee Hatcheries; 1991 Supplement Report.

    SciTech Connect

    Scholz, Allan T.; White, Ronald J.; Koehler, Valerie A.

    1992-05-01

    Previous investigations have determined that thyroid hormone surges activate olfactory imprinting in anadromous salmonid smolts. The mechanism of action appears to require binding of thyroid hormones to receptors in brain cell nuclei, which stimulates neuron differentiation and wires a pattern of neuron circuitry that allows for the permanent storage of the imprinted olfactory memory. In this study, thyroxine concentrations [T{sub 4}] were measured in 487 Lake Whatcom stock and 70 Lake Roosevelt stock Kokanee salmon to indicate the critical period for imprinting. Eggs, alevins and fry, reared at the Spokane Indian Kokanee Hatchery, were collected from January through August 1991. Sampled fish were flash frozen on dry ice and stored at {minus}80{degrees}C until T{sub 4} was extracted and concentrations determined by radioimmunassay. Mean concentration {+-} SEM of 10--20 individual fish (assayed in duplicate) were determined for each time period. T{sub 4} concentration peaked on the day of hatch at 16.8 ng/g body weight and again at swim-up at 16.0 {+-} 4.7 ng/g body weight. T{sub 4} concentration was 12.5 to 12.9 ng/g body weight in eggs, 7.1 to 15.2 ng/g body weight in. alevins, 4.5 to 11.4 ng/g body weight in 42 to 105 day old fry and 0.1 to 2.9 ng/g body weight in 112 to 185 day old fry. T{sub 4} concentrations were highest in eggs at 13.3 {+-} 2.8 ng/g body weight, then steadily decreased to 0.1 {+-} 0.1 ng/g body weight in older fry. Fry were released in Lake Roosevelt tributaries in July and August 1991, at about 170--180 days post hatching, in order to imprint them to those sites. The results of this study indicate that the time of release was not appropriate for imprinting. If T{sub 4} levels are an accurate guide for imprinting in kokanee, our results suggest that the critical period for imprinting in kokanee is at hatching or swim-up stages.

  1. A feasible approach for preparing remanence enhanced NdFeB based permanent magnetic composites

    NASA Astrophysics Data System (ADS)

    Su, K. P.; Liu, Z. W.; Yu, H. Y.; Zhong, X. C.; Qiu, W. Q.; Zeng, D. C.

    2011-04-01

    NdFeB based permanent magnetic nanocomposites were prepared by depositing soft magnetic Fe, Co, or Fe65Co35 nanoparticles on the melt spun NdFeB powders with near single phase composition by a chemical reduction method. The effects of the reduction process, the composition, and the concentrations of metal ions on the magnetic properties of nanocomposites were investigated. Introducing and increasing soft nanoparticle content improved the remanence and maximum energy product of the nanocomposites at the expense of coercivity. Fe65Co35 coated NdFeB powders had higher remanence and energy product than Co or Fe coated powders. The inter-grain exchange coupling between hard and soft magnetic grains was demonstrated by the smooth demagnetization curve with high remanent polarization. Remanence enhanced bulk magnets were also fabricated by consolidating the nanocomposite powders using spark plasma sintering (SPS) technique.

  2. Enhancing C3 photosynthesis: an outlook on feasible interventions for crop improvement.

    PubMed

    Singh, Jitender; Pandey, Prachi; James, Donald; Chandrasekhar, Kottakota; Achary, V Mohan Murali; Kaul, Tanushri; Tripathy, Baishnab C; Reddy, Malireddy K

    2014-12-01

    Despite the declarations and collective measures taken to eradicate hunger at World Food Summits, food security remains one of the biggest issues that we are faced with. The current scenario could worsen due to the alarming increase in world population, further compounded by adverse climatic conditions, such as increase in atmospheric temperature, unforeseen droughts and decreasing soil moisture, which will decrease crop yield even further. Furthermore, the projected increase in yields of C3 crops as a result of increasing atmospheric CO2 concentrations is much less than anticipated. Thus, there is an urgent need to increase crop productivity beyond existing yield potentials to address the challenge of food security. One of the domains of plant biology that promises hope in overcoming this problem is study of C3 photosynthesis. In this review, we have examined the potential bottlenecks of C3 photosynthesis and the strategies undertaken to overcome them. The targets considered for possible intervention include RuBisCO, RuBisCO activase, Calvin-Benson-Bassham cycle enzymes, CO2 and carbohydrate transport, and light reactions among many others. In addition, other areas which promise scope for improvement of C3 photosynthesis, such as mining natural genetic variations, mathematical modelling for identifying new targets, installing efficient carbon fixation and carbon concentrating mechanisms have been touched upon. Briefly, this review intends to shed light on the recent advances in enhancing C3 photosynthesis for crop improvement. PMID:25196090

  3. Feasibility of multi-spectral imaging system to provide enhanced demarcation for skin tumor resection

    NASA Astrophysics Data System (ADS)

    de Roode, Rowland; Noordmans, Herke Jan; Verdaasdonk, Rudolf

    2007-02-01

    Invading tumors like basal cell carcinoma have usually no distinct demarcation for the human eye. Therefore, during resection, an additional rim around the tumor is removed. However, extending sprouts can be missed since most lesions are not uniform. To improve the visualization of the tumor demarcation, we developed a multi-spectral imaging system especially adapted for dermatological applications based on tunable liquid crystal spectral tunable filter technology and LED illumination. Enhanced visualization of skin tumor demarcation was achieved using three strategies. The first strategy is based on creating false color images by combining narrow band spectral filtered images by placing them into the red, green and blue image components of a color image at three specific wavelengths. These specific wavelengths were determined using a trial on error tool to achieve the highest contrast between malignant and healthy tissue. The second strategy is to make ratio images of narrow band spectral filtered images at specific wavelengths. A trail on error tool was created which enables the user to try multiple wavelengths to obtain optimal contrast. This method could be applied in realtime. For the third strategy, on pixel spectral segmentation is applied by selecting the pixel spectra in the center of a tumor, surrounding tissue and healthy tissue far away from the tumor. The correlation between these specific spectra and all image pixels is calculated using a fast algorithm. The degree is correlation is graded by color coding and presented in a false color images showing a detailed demarcation of suspicious regions in the tissue. Although this strategy is expected to provide a higher specificity, it takes more time to calculate than the first strategy.

  4. Improved dosimetry in prostate brachytherapy using high resolution contrast enhanced magnetic resonance imaging: a feasibility study

    PubMed Central

    Morancy, Tye; Kaplan, Irving; Qureshi, Muhammad M.; Hirsch, Ariel E.; Rofksy, Neil M.; Holupka, Edward; Oismueller, Renee; Hawliczek, Robert; Helbich, Thomas H.; Bloch, B. Nicolas

    2014-01-01

    Purpose To assess detailed dosimetry data for prostate and clinical relevant intra- and peri-prostatic structures including neurovascular bundles (NVB), urethra, and penile bulb (PB) from postbrachytherapy computed tomography (CT) versus high resolution contrast enhanced magnetic resonance imaging (HR-CEMRI). Material and methods Eleven postbrachytherapy prostate cancer patients underwent HR-CEMRI and CT imaging. Computed tomography and HR-CEMRI images were randomized and 2 independent expert readers created contours of prostate, intra- and peri-prostatic structures on each CT and HR-CEMRI scan for all 11 patients. Dosimetry data including V100, D90, and D100 was calculated from these contours. Results Mean V100 values from CT and HR-CEMRI contours were as follows: prostate (98.5% and 96.2%, p = 0.003), urethra (81.0% and 88.7%, p = 0.027), anterior rectal wall (ARW) (8.9% and 2.8%, p < 0.001), left NVB (77.9% and 51.5%, p = 0.002), right NVB (69.2% and 43.1%, p = 0.001), and PB (0.09% and 11.4%, p = 0.005). Mean D90 (Gy) derived from CT and HR-CEMRI contours were: prostate (167.6 and 150.3, p = 0.012), urethra (81.6 and 109.4, p = 0.041), ARW (2.5 and 0.11, p = 0.003), left NVB (98.2 and 58.6, p = 0.001), right NVB (87.5 and 55.5, p = 0.001), and PB (11.2 and 12.4, p = 0.554). Conclusions Findings of this study suggest that HR-CEMRI facilitates accurate and meaningful dosimetric assessment of prostate and clinically relevant structures, which is not possible with CT. Significant differences were seen between CT and HR-CEMRI, with volume overestimation of CT derived contours compared to HR-CEMRI. PMID:25834576

  5. Enhanced molten salt purification by electrochemical methods: feasibility experiments with flibe

    SciTech Connect

    Alan K Wertsching; Brandon S Grover; Pattrick Calderoni

    2010-09-01

    -chemistry properties in heat transport systems’ describes the options available to reach such objectives and contains extended references to published work. The report highlights how electrochemical methods are the most promising techniques for the development of instrumentation aimed at the measurement of melts composition and for enhanced purification systems. The purpose of this work is to summarize preliminary experimental activities performed at the INL Safety and Tritium Applied Research facility in support of the development of electrochemistry based instrumentation and purification systems. The experiments have been focused on the LiF-BeF2 eutectic (67 and 33 mol%, respectively), also known as flibe.

  6. Kokanee Stock Status and Contribution of Cabinet Gorge Hatchery, Lake Pend Oreille, Idaho, 1986 Annual Progress Report.

    SciTech Connect

    Bowles, Edward C.

    1987-02-01

    Estimated kokanee (Oncorhynchus nerka) abundance in Lake Pend Oreille was 4.3 million during September 1986. This estimate was similar to 1985 and indicates continued suppression of the kokanee population since initial decline in the late 1960s. Atypically high survival of wild fry resulted in similar fry recruitment in 1986 as 1985, whereas hatchery-reared fry contributed only 8% to total fry recruitment as a result of low post-release survival (3%). Fry released into the Clark Fork River from Cabinet Gorge Hatchery had very low survival during emigration to Lake Pend Oreille, resulting from poor flow conditions and potentially high predation. Fry survival during emigration was twice as high during nighttime flows of 16,000 cfs than 7,800 cfs. Emigration also was faster during higher flows. Several marks were tested to differentially mark fry release groups to help determine impacts of flow and other factors on fry survival. Survival of fry marked with tetracycline and fluorescent dye was high (>99%) during the 10-week study. In contrast, survival of fry marked with fluorescent grit marks ranged from 5 to 93%, depending on application pressure and distance from the fry. Retention was high (>96%) for tetracycline and grit marks during the study, whereas dye marks were discernible (100%) for only one week. 23 refs., 20 figs., 10 tabs.

  7. Kokanee Stock Status and Contribution of Cabinet Gorge Hatchery, Lake Pend Oreille, Idaho, 1989 Annual Progress Report.

    SciTech Connect

    Hoelscher, Brian

    1990-04-01

    The kokanee Oncorhynchus nerka rehabilitation program for Lake Pend Oreille continued to show progress during 1989. Estimated kokanee abundance in late August was 7.71 million fish. Decreased population size is the result of lower hatchery and wild fry recruitment and low age 1+ survival. Lower recruitment of wild fry in 1989 resulted from a smaller parental escapement in 1988 and lower wild fry survival. Six fry release strategies were evaluated in 1989. Two groups were released in Clark Fork River to help improve a spawning run to Cabinet Gorge Hatchery. Survival from the mid-summer release, which was barged down Clark Fork River to avoid low flow problems, was not significantly different from the early release. The final assessment of these release strategies will be evaluated when adults return to Cabinet gorge Hatchery in 1992 and 1993. Fry released to support the Sullivan Springs Creek spawning run also survived will in 1989. Two open-water releases were made during early and mid-summer. 30 refs., 26 figs., 2 tabs.

  8. Bathymetry, morphology, and lakebed geologic characteristics of potential Kokanee salmon spawning habitat in Lake Pend Oreille, Bayview and Lakeview quadrangles, Idaho

    USGS Publications Warehouse

    Barton, Gary J.; Dux, Andrew M.

    2013-01-01

    Kokanee salmon (Oncorhynchus nerka) are a keystone species in Lake Pend Oreille in northern Idaho, historically supporting a high-yield recreational fishery and serving as the primary prey for the threatened native bull trout (Salvelinus confluentus) and the Gerrard-strain rainbow trout (Oncorhynchus mykiss). After 1965, the kokanee population rapidly declined and has remained at a low level of abundance. Lake Pend Oreille is one of the deepest lakes in the United States, the largest lake in Idaho, and home to the U.S. Navy Acoustic Research Detachment Base. The U.S. Geological Survey and Idaho Department of Fish and Game are mapping the bathymetry, morphology, and the lakebed geologic units and embeddedness of potential kokanee salmon spawning habitat in Lake Pend Oreille. Relations between lake morphology, lakebed geologic units, and substrate embeddedness are characterized for the shore zone, rise zone, and open water in bays and the main stem of the lake. This detailed knowledge of physical habitat along the shoreline of Lake Pend Oreille is necessary to better evaluate and develop kokanee recovery actions.

  9. Lake Roosevelt Fisheries Evaluation Program; Evaluation of Limiting Factors for Stocked Kokanee and Rainbow Trout in Lake Roosevelt, Washington, 1999 Annual Report.

    SciTech Connect

    Baldwin, Casey; Polacek, Matt

    2009-03-01

    Hatchery supplementation of kokanee Oncorhynchus nerka and rainbow trout O. mykiss has been the primary mitigation provided by Bonneville Power Administration for loss of anadromous fish to the waters above Grand Coulee Dam (GCD). The hatchery program for rainbow trout has consistently met management goals and provided a substantial contribution to the fishery; however, spawner returns and creel survey results for kokanee have been below management goals. Our objective was to identify factors that limit limnetic fish production in Lake Roosevelt by evaluating abiotic conditions, food limitations, piscivory, and entrainment. Dissolved oxygen concentration was adequate throughout most of the year; however, levels dropped to near 6 mg/L in late July. For kokanee, warm water temperatures during mid-late summer limited their nocturnal distribution to 80-100 m in the lower section of the reservoir. Kokanee spawner length was consistently several centimeters longer than in other Pacific Northwest systems, and the relative weights of rainbow trout and large kokanee were comparable to national averages. Large bodied daphnia (> 1.7 mm) were present in the zooplankton community during all seasons indicating that top down effects were not limiting secondary productivity. Walleye Stizostedion vitreum were the primary piscivore of salmonids in 1998 and 1999. Burbot Lota lota smallmouth bass Micropterus dolomieui, and northern pikeminnow Ptychocheilus oregonensis preyed on salmonids to a lesser degree. Age 3 and 4 walleye were responsible for the majority (65%) of the total walleye consumption of salmonids. Bioenergetics modeling indicated that reservoir wide consumption by walleye could account for a 31-39% loss of stocked kokanee but only 6-12% of rainbow trout. Size at release was the primary reason for differential mortality rates due to predation. Entrainment ranged from 2% to 16% of the monthly abundance estimates of limnetic fish, and could account for 30% of total

  10. Application of iron electrode corrosion enhanced electrokinetic-Fenton oxidation to remediate diesel contaminated soils: A laboratory feasibility study

    NASA Astrophysics Data System (ADS)

    Tsai, Tzai-Tang; Sah, Jygau; Kao, Chih-Ming

    2010-01-01

    SummaryDiesel soil contamination on gas stations or refinery plants is a worldwide environmental problem. The main objectives of this study were to (1) evaluate the efficiency of electrokinetic (EK) by using different electrode materials (graphite and iron rods) and electrolytes (tap water, 0.01 M NaCl, and 0.1 M NaCl) on the remediation of diesel contaminated soils, and (2) evaluate the feasibility of total petroleum hydrocarbon-diesel (TPH-D) reducing in soils via EK-Fenton oxidation enhanced by corroded iron electrode. The EK and EK-Fenton experiments were conducted in batch and sand box experiments, respectively. Batch experiments reveal that the most appropriate electrolyte was 0.1 M NaCl when iron electrode was used in the EK system. Sand box experiments indicate that the TPH-D concentration dropped from 10,000 to 300 mg kg -1 when amorphous iron/total iron (Fe o/Fe t) ratio increased from 0.1 to 0.33, with the addition of 8% of H 2O 2 and 0.1 M NaCl after 60 days of EK-Fenton operation. Electrokinetically enhanced oxidation with the presence of both H 2O 2 and Fe 3O 4 (iron electrode corrosion) resulted in higher TPH-D removal efficiency (97%) compared to the efficiencies observed from EK (55%) or Fenton oxidation (27%) alone. This demonstrates that EK-Fenton oxidation catalyzed by iron electrode corrosion is a valuable direction to efficiently and effectively remediate diesel contaminated soils.

  11. Feasibility of iodine contrast enhanced CT-scan during a 18F-fluorodeoxyglucose Positron Emission Tomography

    NASA Astrophysics Data System (ADS)

    Houzard, C.; Tychyj, C.; Morelec, I.; Ricard, F.; Got, P.; Cotton, F.; Giammarile, F.; Maintas, D.

    2009-06-01

    OBJECTIVE: this prospective study evaluates the feasibility in current clinical practice of contrast enhanced CT-scan for diagnosis purpose, performed during 18FDG PET-CT study with a PET/CT tomography. METHOD: 25 patients underwent FDG imaging for lymphoma staging. The PET scan was done immediately after the usual low dose CT (lCT). A second CT scan was consequently acquired, by using classical diagnosis CT parameters (dCT) and iodinated contrast. For each patient, all CT attenuation correction (CTAC) PET images were visually compared. Density in Hounsfield units (HU) and maximum Standardized Uptake Value (SUVmax) were then measured on different organs and up to 5 specific lymphoma localizations (total of 294 measurements). RESULTS: Visual analysis was similar for the 2 modalities, without discordant interpretation for the pathologic sites. SUVmax means and standard deviation of each organ for lCTAC and dCTAC were comparable. The equation of the fitted multiple linear regression model was: dCT=0.0748191 + 1.17024*lCT (98.71%; p < 0.01). CONCLUSION: These first results allow the use of injected CT scan, before the PET scan acquisition for lymphoma staging with this PET-CT scan, not affected by the height atomic number and elevated density. A great benefit is therefore obtained on diagnostic, logistic and radioprotection purposes.

  12. Enhancing the Feasibility of Microcystis aeruginosa as a Feedstock for Bioethanol Production under the Influence of Various Factors.

    PubMed

    Khan, Muhammad Imran; Lee, Moon Geon; Seo, Hyo Jin; Shin, Jin Hyuk; Shin, Tai Sun; Yoon, Yang Ho; Kim, Min Yong; Choi, Jong Il; Kim, Jong Deog

    2016-01-01

    Microcystis aeruginosa, a freshwater microalga, is capable of producing and accumulating different types of sugars in its biomass which make it a good feedstock for bioethanol production. Present study aims to investigate the effect of different factors increasing growth rate and carbohydrates productivity of M. aeruginosa. MF media (modified BG11 media) and additional ingredients such as aminolevulinic acid (2 mM), lysine (2.28 mM), alanine (1 mM), and Naphthalene acetic acid (1 mM) as cytokine promoted M. aeruginosa growth and sugar contents. Salmonella showed growth-assisting effect on M. aeruginosa. Enhanced growth rate and carbohydrates contents were observed in M. aeruginosa culture grown at 25°C under red LED light of 90 μmolm(-2)s(-1) intensity. More greenish and carbohydrates rich M. aeruginosa biomass was prepared (final OD660 nm = 2.21 and sugar contents 10.39 mM/mL) as compared to control (maximum OD660 nm = 1.4 and sugar contents 3 mM/mL). The final algae biomass was converted to algae juice through a specific pretreatment method. The resulted algae Juice was used as a substrate in fermentation process. Highest yield of bioethanol (50 mM/mL) was detected when Brettanomyces custersainus, Saccharomyces cerevisiae, and Pichia stipitis were used in combinations for fermentation process as compared to their individual fermentation. The results indicated the influence of different factors on the growth rate and carbohydrates productivity of M. aeruginosa and its feasibility as a feedstock for fermentative ethanol production. PMID:27556034

  13. Enhancing the Feasibility of Microcystis aeruginosa as a Feedstock for Bioethanol Production under the Influence of Various Factors

    PubMed Central

    Lee, Moon Geon; Seo, Hyo Jin; Shin, Jin Hyuk; Shin, Tai Sun; Kim, Min Yong; Choi, Jong Il

    2016-01-01

    Microcystis aeruginosa, a freshwater microalga, is capable of producing and accumulating different types of sugars in its biomass which make it a good feedstock for bioethanol production. Present study aims to investigate the effect of different factors increasing growth rate and carbohydrates productivity of M. aeruginosa. MF media (modified BG11 media) and additional ingredients such as aminolevulinic acid (2 mM), lysine (2.28 mM), alanine (1 mM), and Naphthalene acetic acid (1 mM) as cytokine promoted M. aeruginosa growth and sugar contents. Salmonella showed growth-assisting effect on M. aeruginosa. Enhanced growth rate and carbohydrates contents were observed in M. aeruginosa culture grown at 25°C under red LED light of 90 μmolm−2s−1 intensity. More greenish and carbohydrates rich M. aeruginosa biomass was prepared (final OD660 nm = 2.21 and sugar contents 10.39 mM/mL) as compared to control (maximum OD660 nm = 1.4 and sugar contents 3 mM/mL). The final algae biomass was converted to algae juice through a specific pretreatment method. The resulted algae Juice was used as a substrate in fermentation process. Highest yield of bioethanol (50 mM/mL) was detected when Brettanomyces custersainus, Saccharomyces cerevisiae, and Pichia stipitis were used in combinations for fermentation process as compared to their individual fermentation. The results indicated the influence of different factors on the growth rate and carbohydrates productivity of M. aeruginosa and its feasibility as a feedstock for fermentative ethanol production. PMID:27556034

  14. The 2006 Project Progress Report for 1987-099-00 Dworshak Kokanee Population and Entrainment Assessment (contract # 26850) is attached to project 2007-003-00, contract #31598. [POINTER

    SciTech Connect

    2008-12-18

    During this contract, we continued testing underwater strobe lights to determine their effectiveness at repelling kokanee Oncorhynchus nerka away from Dworshak Dam. Strobe light tests were conducted on four nights from April 24-27, 2006, in front of the middle reservoir outlet (RO) 2. The density and distribution of fish, (thought to be mostly kokanee), were monitored with a split-beam echo sounder. We then compared fish counts and densities during nights when the lights were flashing to counts and densities during adjacent nights without the lights on. On two nights, April 25 and 27, 2006, when no lights were present, fish counts near RO 2 averaged 12.4 fish and densities averaged 31.0 fish/ha. When strobe lights were turned on during the nights of April 24 and 26, mean counts dropped to 4.7 fish and densities dropped to 0.5 fish/ha. The decline in counts (62%) and densities (99%) was statistically significant (p = 0.009 and 0.002, respectively). Test results indicated that strobe lights were able to reduce fish densities by at least 50% in front of a discharging reservoir outlet, which would be sufficient to improve sport fish harvest. We also used split-beam hydroacoustics to monitor the kokanee population in Dworshak Reservoir during 2006. Estimated abundance of kokanee increased from the 2005 population estimate. Based on hydroacoustic surveys, we estimated approximately 5,815,000 kokanee (90% CI {+-} 27.6%) in Dworshak Reservoir in August 2006. This included 2,183,000 age-0 (90% CI {+-} 24.2%), 1,509,000 age-1 (90% CI {+-} 29.0%), and 2,124,000 age-2 (90% CI {+-} 27.6%) kokanee. This resulted in a density of age-2 kokanee above the management goal of 30-50 adults/ha. Entrainment sampling was conducted with fixed-site, split-beam hydroacoustics from May through September for a continuous 24 h period when dam operations permitted. The highest fish detection rates from entrainment assessments were found during dawn periods, unlike previous year's results, which

  15. Effect of the Operation of Kerr and Hungry Horse Dams on the Reproduction Success of Kokanee in the Flathead River System, 1986 Annual Progress Report.

    SciTech Connect

    Beattie, Will; Clancey, Patrick

    1987-03-01

    The 1985 kokanee spawning run in the Flathead system was the strongest in five years. Escapement to the Flathead River system was 147,000 fish, including 123,000 in McDonald Creek and an estimated 20,000 in the main stem. Enumeration of spawners and redds in the Flathead River was hindered by high fall flows and early freezing in November. The upstream spawning migration from Flathead Lake began in late August. Schools of kokanee were seen six miles above the lake on September 4. We counted 1,156 redds in Flathead Lake, distributed primarily along the southeastern shore. An unusually high proportion (90 percent) of lakeshore spawning occurred in the zone above minimum pool, where egg mortality is very high because of exposure from drawdown. Escapement to the Swan River was 1,350 fish. Four year old (III+) fish comprised 95 percent of the spawning run in the Flathead system. This continues a five-year trend toward dominance of the III+ year class. The age composition of spawners has varied considerably for the past 15 years. The average size of spawning fish was 365 mm, which is identical to the average size of the parent year class in 1981. One of the goals of managing Flathead kokanee is to produce mature fish 300-330 mm in length. In the main stem Flathead River, pre-emergent survival was 80 percent. Survival in McDonald Creek, unaffected by hydroelectric operations, was 83 percent. Sampling showed few hatched alevins, probably due to unusually cold winter temperatures. Egg survival at Blue Bay, a spawning area on Flathead Lake where redds are concentrated below minimum pool, varied in relation to depth and dissolved oxygen concentration in the substrate. Eggs survived 78 days at 2,880 feet where dissolved oxygen was 5.7 mg/l. Eggs survived 35 days at 2,870 feet where dissolved oxygen concentration averaged 2.9 mg/l. Low dissolved oxygen contributed to poor survival to emergence at all elevations in Blue Ray. Experiments in Skidoo Bay confirmed that survival of

  16. Feasibility of enhancing the DEnitrifying AMmonium OXidation (DEAMOX) process for nitrogen removal by seeding partial denitrification sludge.

    PubMed

    Cao, Shenbin; Peng, Yongzhen; Du, Rui; Wang, Shuying

    2016-04-01

    The recently proposed DEnitrifying AMmonium OXidation (DEAMOX) process combined anaerobic ammonia oxidation (ANAMMOX) with denitrification to convert nitrate to nitrite, which was a promising way for treating wastewater containing nitrate and ammonia. This study investigated the feasibility of establishing DEAMOX process by seeding partial denitrification sludge (NO3(-) → NO2(-)) using sodium acetate as an electron donor in a sequencing batch reactor. Results showed that the DEAMOX process was established successfully and operated stably in 114-days operation. The average effluent total nitrogen concentration was below 5 mg L(-1) and TN removal efficiency reached up to 97% at COD/NO3(-) ratio of 3.0 under initial NH4(+) concentration of 25 mg L(-1) and NO3(-) of 30 mg L(-1). It suggested that the presence of NO2(-) in the system supplied for ANAMMOX and the relatively long sludge retention time (SRT) for denitrifiers were attributed to commendable coexistence of ANAMMOX and denitrifying bacteria. PMID:26829308

  17. Contrast enhanced ultrasound with quantitative perfusion analysis for objective characterization of pancreatic ductal adenocarcinoma: A feasibility study.

    PubMed

    D'Onofrio, Mirko; Canestrini, Stefano; Crosara, Stefano; De Robertis, Riccardo; Pozzi Mucelli, Roberto

    2014-03-28

    The aim of this study was to determine whether contrast enhanced ultrasound (CEUS) quantitative perfusion analysis allows an objective characterization of ductal adenocarcinoma (ADK) of the pancreas. Patients with pancreatic ADK underwent CEUS. All examinations were performed on an Acuson S2000 system (Siemens, Erlangen, Germany) after the iv administration of 2.4 mL contrast agent (SonoVue(®), Bracco, Milan, Italy). All lesions were pathologically proved. An operator manually drew different regions of interest within the tumor and the adjacent parenchyma to allow the quantitative perfusion analysis. The mean values of peak of enhancement, time to peak and ascending curve were calculated and compared using the Student's t test. The quantitative perfusion analysis was possible in all lesions. The mean values of the peak of enhancement, time to peak and ascending curve were 17.19%, 7.97 s and 159.52% s within the tumor and 33.57%, 8.89 s and 355.29% s within the adjacent parenchyma. The peak of enhancement and the ascending curve values were significantly different within the tumor and the adjacent parenchyma. Thus, CEUS allows the quantitative perfusion analysis of pancreatic ductal adenocarcinoma. PMID:24765238

  18. A Framework of Three Learning Activity Levels for Enhancing the Usability and Feasibility of Wireless Learning Environments

    ERIC Educational Resources Information Center

    Wang, Hsue-Yie; Liu, Tzu-Chien; Chou, Chih-Yueh; Liang, Jen-Kai; Chan, Tak-Wai; Yang, Stephen

    2004-01-01

    The most recent advances in information technology have brought wireless communication and mobile devices to education. The wireless technology enhanced classroom (WiTEC) integrates a wireless local area network, mobile learning devices, and client-server architecture to support instruction and learning activities. This article introduces a…

  19. Contrast enhanced ultrasound with quantitative perfusion analysis for objective characterization of pancreatic ductal adenocarcinoma: A feasibility study

    PubMed Central

    D’Onofrio, Mirko; Canestrini, Stefano; Crosara, Stefano; Robertis, Riccardo De; Mucelli, Roberto Pozzi

    2014-01-01

    The aim of this study was to determine whether contrast enhanced ultrasound (CEUS) quantitative perfusion analysis allows an objective characterization of ductal adenocarcinoma (ADK) of the pancreas. Patients with pancreatic ADK underwent CEUS. All examinations were performed on an Acuson S2000 system (Siemens, Erlangen, Germany) after the iv administration of 2.4 mL contrast agent (SonoVue®, Bracco, Milan, Italy). All lesions were pathologically proved. An operator manually drew different regions of interest within the tumor and the adjacent parenchyma to allow the quantitative perfusion analysis. The mean values of peak of enhancement, time to peak and ascending curve were calculated and compared using the Student’s t test. The quantitative perfusion analysis was possible in all lesions. The mean values of the peak of enhancement, time to peak and ascending curve were 17.19%, 7.97 s and 159.52% s within the tumor and 33.57%, 8.89 s and 355.29% s within the adjacent parenchyma. The peak of enhancement and the ascending curve values were significantly different within the tumor and the adjacent parenchyma. Thus, CEUS allows the quantitative perfusion analysis of pancreatic ductal adenocarcinoma. PMID:24765238

  20. Enhancing the Return to Work of Cancer Survivors: Development and Feasibility of the Nurse-Led eHealth Intervention Cancer@Work

    PubMed Central

    van Hezel, Sanne; de Boer, Angela GEM; Frings-Dresen, Monique HW

    2016-01-01

    Background It is important to enhance the return to work of cancer survivors with an appropriate intervention, as cancer survivors experience problems upon their return to work but consider it an essential part of their recovery. Objective The objective of our study was to develop an eHealth intervention to enhance the return to work of cancer survivors and to test the feasibility of the eHealth intervention with end users. Methods To develop the intervention we 1) searched the literature, 2) interviewed 7 eHealth experts, 3) interviewed 7 cancer survivors, 2 employers, and 7 occupational physicians, and 4) consulted experts. To test feasibility, we enrolled 39 cancer survivors, 9 supervisors, 7 occupational physicians, 9 general physicians and 2 social workers and gave them access to the eHealth intervention. We also interviewed participants, asked them to fill in a questionnaire, or both, to test which functionalities of the eHealth intervention were appropriate and which aspects needed improvement. Results Cancer survivors particularly want information and support regarding the possibility of returning to work, and on financial and legal aspects of their situation. Furthermore, the use of blended care and the personalization of the eHealth intervention were preferred features for increasing compliance. The first version of the eHealth intervention consisted of access to a personal and secure website containing various functionalities for cancer survivors blended with support from their specialized nurse, and a public website for employers, occupational physicians, and general physicians. The eHealth intervention appeared feasible. We adapted it slightly by adding more information on different cancer types and their possible effects on return to work. Conclusions A multistakeholder and mixed-method design appeared useful in the development of the eHealth intervention. It was challenging to meet all end user requirements due to legal and privacy constraints. The e

  1. Feasibility of using a humanoid robot for enhancing attention and social skills in adolescents with autism spectrum disorder.

    PubMed

    Jordan, Kimberlee; King, Marcus; Hellersteth, Sophia; Wirén, Anna; Mulligan, Hilda

    2013-09-01

    This study investigated the use of robotic technology for promoting attention, communication and social skills in adolescents with autism spectrum disorder (ASD). Attention, communication and social skills were measured while participants played a memory card matching game (Face Match) using (a) a humanoid robot, (b) a Smart Board and (c) playing cards. Three participants with ASD and three with other cognitive impairments were recruited from a secondary school with a special needs unit. Participants were paired such that one of each pair had a diagnosis of ASD and Face Match was played in these pairs for ∼15 min, with a game organizer present. On 3 separate days, video recordings were made as the participants played Face Match; a different game mode (robot, Smart Board, playing cards) was used each day. A system for categorizing attention, communication and social skills was developed that described 16 subcategories of interactions and intra-actions. In general, participants with ASD showed highly individualized patterns of behaviour in the three different modes. However, repetitive behaviour was reduced in participants with ASD when using both the robot and the Smart Board compared with playing cards. We show that it is feasible to use a robot to assist teaching of social skills to adolescents with ASD, but suggest that the robot features could be further explored and utilized. PMID:23328816

  2. Numerical simulation to study the feasibility of using CO2 as a stimulation agent for enhanced geothermal systems

    SciTech Connect

    Xu, T.; Zhang, W.; Pruess, K.

    2009-11-15

    A major concern in the development of enhanced geothermal systems (EGS) is achieving and maintaining adequate injectivity, while avoiding the development of preferential short-circuiting flow paths such as those caused by thermally-induced stress cracking. Past researches have tended to focus primarily on thermal and hydraulic stimulation. Recent studies suggest that chemical stimulation may improve the performance of EGS reservoirs. Geothermal injection wells are often drilled into formations containing reactive minerals such as calcite. Injecting aqueous chemical agents such as mineral acids, could be effective for mineral dissolution and porosity enhancement at distances of several meters around a well. An alternative to treatment with strong acids is the use of supercritical (SC) CO{sub 2} as stimulation agent for an aqueous-based EGS. Reactive transport modeling is used to investigate the effectiveness of this method. We used the thermal condition and mineralogical composition from a well of Desert Peak EGS site, to examine ways in which mixtures of water and CO{sub 2} can be injected to enhance porosity.

  3. Time scale matters: genetic analysis does not support adaptation-by-time as the mechanism for adaptive seasonal declines in kokanee reproductive life span

    PubMed Central

    Morbey, Yolanda E; Jensen, Evelyn L; Russello, Michael A

    2014-01-01

    Seasonal declines of fitness-related traits are often attributed to environmental effects or individual-level decisions about reproductive timing and effort, but genetic variation may also play a role. In populations of Pacific salmon (Oncorhynchus spp.), seasonal declines in reproductive life span have been attributed to adaptation-by-time, in which divergent selection for different traits occurs among reproductively isolated temporal components of a population. We evaluated this hypothesis in kokanee (freshwater obligate Oncorhynchus nerka) by testing for temporal genetic structure in neutral and circadian-linked loci. We detected no genetic differences in presumably neutral loci among kokanee with different arrival and maturation dates within a spawning season. Similarly, we detected no temporal genetic structure in OtsClock1b, Omy1009uw, or OmyFbxw11, candidate loci associated with circadian function. The genetic evidence from this study and others indicates a lack of support for adaptation-by-time as an important evolutionary mechanism underlying seasonal declines in reproductive life span and a need for greater consideration of other mechanisms such as time-dependent, adaptive adjustment of reproductive effort. PMID:25478160

  4. Follow-up of atheroma burden with sequential whole body contrast enhanced MR angiography: a feasibility study.

    PubMed

    Weir-McCall, Jonathan R; White, Richard D; Ramkumar, Prasad G; Gandy, Stephen J; Khan, Faisel; Belch, Jill J F; Struthers, Allan D; Houston, J Graeme

    2016-05-01

    Assess the feasibility of whole body magnetic resonance angiography (WB-MRA) for monitoring global atheroma burden in a population with peripheral arterial disease (PAD). 50 consecutive patients with symptomatic PAD referred for clinically indicated MRA were recruited. Whole body MRA (WB-MRA) was performed at baseline, 6 months and 3 years. The vasculature was split into 31 anatomical arterial segments. Each segment was scored according to degree of luminal narrowing: 0 = normal, 1 = <50 %, 2 = 50-70 %, 3 = 71-99 %, 4 = vessel occlusion. The score from all assessable segments was summed, and then normalised to the number of assessable vessels. This normalised score was divided by four (the maximum vessel score) and multiplied by 100 to give a final standardised atheroma score (SAS) with a score of 0-100. Progression was assessed with repeat measure ANOVA. 36 patients were scanned at 0 and 6 months, with 26 patients scanned at the 3 years follow up. Only those who completed all three visits were included in the final analysis. Baseline atherosclerotic burden was high with a mean SAS of 15.7 ± 10.3. No significant progression was present at 6 months (mean SAS 16.4 ± 10.5, p = 0.67), however there was significant disease progression at 3 years (mean SAS 17.7 ± 11.5, p = 0.01). Those with atheroma progression at follow-up were less likely to be on statin therapy (79 vs 100 %, p = 0.04), and had significantly higher baseline SAS (17.6 ± 11.2 vs 10.7 ± 5.1, p = 0.043). Follow up of atheroma burden is possible with WB-MRA, which can successfully quantify and monitor atherosclerosis progression at 3 years follow-up. PMID:26809611

  5. Impact and feasibility of the Allied Health Professional Enhancement Program placements – experiences from rural and remote Queensland

    PubMed Central

    Martin, Priya; Kumar, Saravana; Stone, Melinda; Abernathy, LuJuana; Burge, Vanessa; Lizarondo, Lucylynn

    2016-01-01

    Background Allied health professionals practicing in rural and remote areas are often faced with barriers that prevent them from accessing professional development opportunities. In order to address this barrier, a tailored professional development program was developed and implemented by the Cunningham Centre in Queensland, Australia. The purpose of this study was to investigate the benefits of the program to participants and their work units. Methods This study used a concurrent mixed methods longitudinal design to investigate the medium- to long-term benefits of one Allied Health Professional Enhancement Program placement. Surveys and individual interviews provided data at 2 weeks and at 6 months post-placement. The study participants included the placement participant (a physiotherapist), their line manager, clinical supervisor, and the placement facilitator. Results Results demonstrated that the placement resulted in various reported benefits to the placement participant, as well as to service delivery in their home location. Benefits of the placement reported by the participant included increased confidence, improved knowledge and skills, increased access to professional networks, and validation of practice. Benefits to service delivery reported included improved efficiencies, improved patient outcomes, and positive impact on other team members. Discussion This study found that the Allied Health Professional Enhancement Program placement investigated was beneficial to the participant and to service delivery. In addition, the benefits reported were sustained at 6 months post-placement. Despite the fact that this study showcases experiences from one setting, the findings from this study and the lessons learnt may be transferrable to other similar programs elsewhere due to its methodological strengths (such as rich descriptions of the program and use of typical case sampling). While this study provides emergent evidence of usefulness of the program to

  6. Feasibility of the Enhancing Participation In the Community by improving Wheelchair Skills (EPIC Wheels) program: study protocol for a randomized controlled trial

    PubMed Central

    2013-01-01

    Background Many older adults rely on a manual wheelchair for mobility but typically receive little, if any, training on how to use their wheelchair effectively and independently. Standardized skill training is an effective intervention, but limited access to clinician trainers is a substantive barrier. Enhancing Participation in the Community by Improving Wheelchair Skills (EPIC Wheels) is a 1-month monitored home training program for improving mobility skills in older novice manual wheelchair users, integrating principles from andragogy and social cognitive theory. The purpose of this study is to determine whether feasibility indicators and primary clinical outcome measures of the EPIC Wheels program are sufficiently robust to justify conducting a subsequent multi-site randomized controlled trial. Methods A 2 × 2 factorial randomized controlled trial at two sites will compare improvement in wheelchair mobility skills between an EPIC Wheels treatment group and a computer-game control group, with additional wheelchair use introduced as a second factor. A total of 40 community-dwelling manual wheelchair users at least 55 years old and living in two Canadian metropolitan cities (n = 20 × 2) will be recruited. Feasibility indicators related to study process, resources, management, and treatment issues will be collected during data collection and at the end of the study period, and evaluated against proposed criteria. Clinical outcome measures will be collected at baseline (pre-randomization) and post-intervention. The primary clinical outcome measure is wheelchair skill capacity, as determined by the Wheelchair Skills Test, version 4.1. Secondary clinical outcome measures include wheelchair skill safety, satisfaction with performance, wheelchair confidence, life-space mobility, divided-attention, and health-related quality of life. Discussion The EPIC Wheels training program offers several innovative features. The convenient, portable, economical, and adaptable

  7. Feasibility of kilovoltage x-ray energy modulation by gaseous media and its application in contrast-enhanced radiotherapy

    SciTech Connect

    Facundo-Flores, E. L.; Garnica-Garza, H. M.

    2013-09-15

    Purpose: To present a method to modulate the energy contents of a kilovoltage x-ray beam that makes use of a gas as the modulating medium. The method is capable of producing arbitrary x-ray spectra by varying the pressure of the modulating gas and the peak kilovoltage (kVp) of the x-ray beams whose energy is being modulated.Methods: An aluminum chamber was machined with a 0.5 cm wall thickness, designed to withstand pressures of more than 80 atm. A pressure sensor and electrovalves were used to monitor and regulate the gas pressure. Argon was used as the modulating gas. A CdTe spectrometer was used to measure x-ray spectra for different combinations of kVp and gas pressure, thus obtaining a set of basis x-ray functions. An arbitrary x-ray spectrum can then be formed by the linear combination of such basis functions. In order to show one possible application of the modulation method, a contrast-enhanced radiotherapy prostate treatment was optimized with respect to the x-ray beam energy, without restrictions on the possible shape of the resultant x-ray spectra.Results: The x-ray spectra basis functions obtained display a smooth and gradual variation of their average energy as a function of the gas pressure for a given kVp, sometimes in the order of 1 or 2 keV. This gradual variation would be difficult to obtain with a conventional aluminum or copper filters, as the change in thickness necessary to reproduce the data presented would be in the order of micrometers, making necessary the use of a large number of such filters. Using the modulation method presented here, the authors were able to reconstruct the optimized x-ray spectra from the measured basis functions, for different optimization objectives.Conclusions: A method has been developed that allows for the controlled modulation of the energy contents of kilovoltage x-ray spectra. The method has been shown to be able to reproduce spectra of arbitrary shape, such as those obtained from the optimization of contrast-enhanced

  8. Feasibility of CO₂/SO₂ uptake enhancement of calcined limestone modified with rice husk ash during pressurized carbonation.

    PubMed

    Chen, Huichao; Zhao, Changsui; Ren, Qiangqiang

    2012-01-01

    The calcination/carbonation cycle using calcium-based sorbents appears to be a viable method for carbon dioxide (CO₂) capture from combustion gases. Recent attempts to improve the CO₂/SO₂ uptake of a calcium-based sorbent modified by using rice husk ash (RHA) in the hydration process have succeeded in enhancing its effectiveness. The optimal mole ratio of RHA to calcined limestone (M(Si/Ca)) was adjusted to 0.2. The cyclic CO₂ capture characteristics and the SO₂ uptake activity of the modified sorbent were evaluated in a calcination/pressurized carbonation reactor system. Scanning electron microscope (SEM) images and X-ray diffraction (XRD) spectrum of the sorbent were also taken to supplement the study. The results showed that the carbonation conversion was greatly increased for the sorbent with M(Si/Ca) ratio of 0.2. For this sorbent formulation the optimal operating conditions were 700-750 °C and 0.5-0.7 MPa. CO₂ absorption was not proportional to CO₂ concentration in the carbonation atmosphere, but was directly related to reaction time. The CO₂ uptake decreased in the presence of SO₂. SO₂ uptake increased, and the total calcium utilization was maintained over multiple cycles. Analysis has shown that the silicate component is evenly or well distributed, and this serves as a framework to prevent sintering, thus preserving the available microstructure for reaction. The sorbent also displayed high activity to SO₂ absorption and could be used to capture CO₂ and SO₂ simultaneously. PMID:22054590

  9. Enhanced relapse prevention for bipolar disorder – ERP trial. A cluster randomised controlled trial to assess the feasibility of training care coordinators to offer enhanced relapse prevention for bipolar disorder

    PubMed Central

    Lobban, Fiona; Gamble, Carol; Kinderman, Peter; Taylor, Lee; Chandler, Claire; Tyler, Elizabeth; Peters, Sarah; Pontin, Eleanor; Sellwood, William; Morriss, Richard K

    2007-01-01

    Background Bipolar Disorder (BD) is a common and severe form of mental illness characterised by repeated relapses of mania or depression. Pharmacotherapy is the main treatment currently offered, but this has only limited effectiveness. A recent Cochrane review has reported that adding psycho-social interventions that train people to recognise and manage the early warning signs of their relapses is effective in increasing time to recurrence, improving social functioning and in reducing hospitalisations. However, the review also highlights the difficulties in offering these interventions within standard mental health services due to the need for highly trained therapists and extensive input of time. There is a need to explore the potential for developing Early Warning Sign (EWS) interventions in ways that will enhance dissemination. Methods and design This article describes a cluster-randomised trial to assess the feasibility of training care coordinators (CCs) in community mental health teams (CMHTs) to offer Enhanced Relapse Prevention (ERP) to people with Bipolar Disorder. CMHTs in the North West of England are randomised to either receive training in ERP and to offer this to their clients, or to continue to offer treatment as usual (TAU). The main aims of the study are (1) to determine the acceptability of the intervention, training and outcome measures (2) to assess the feasibility of the design as measured by rates of recruitment, retention, attendance and direct feedback from participants (3) to estimate the design effect of clustering for key outcome variables (4) to estimate the effect size of the impact of the intervention on outcome. In this paper we provide a rationale for the study design, briefly outline the ERP intervention, and describe in detail the study protocol. Discussion This information will be useful to researchers attempting to carry out similar feasibility assessments of clinical effectiveness trials and in particular cluster randomised

  10. Radiotherapy treatment planning with contrast-enhanced computed tomography: feasibility of dual-energy virtual unenhanced imaging for improved dose calculations

    PubMed Central

    2014-01-01

    Background In radiotherapy treatment planning, intravenous administration of an iodine-based contrast agent during computed tomography (CT) improves the accuracy of delineating target volumes. However, increased tissue attenuation resulting from the high atomic number of iodine may result in erroneous dose calculations because the contrast agent is absent during the actual procedure. The purpose of this proof-of-concept study was to present a novel framework to improve the accuracy of dose calculations using dual-energy virtual unenhanced CT in the presence of an iodine-based contrast agent. Methods Simple phantom experiments were designed to assess the feasibility of the proposed concept. By utilizing a “second-generation” dual-source CT scanner equipped with a tin filter for improved spectral separation, four CT datasets were obtained using both a water phantom and an iodine phantom: “true unenhanced” images with attenuation values of 2 ± 11 Hounsfield Units (HU), “enhanced” images with attenuation values of 274 ± 23 HU, and two series of “virtual unenhanced” images synthesized from dual-energy scans of the iodine phantom, each with a different combination of tube voltages. Two series of virtual unenhanced images demonstrated attenuation values of 12 ± 29 HU (with 80 kVp/140 kVp) and 34 ± 10 HU (with 100 kVp/140 kVp) after removing the iodine component from the contrast-enhanced images. Dose distributions of the single photon beams calculated from the enhanced images and two series of virtual unenhanced images were compared to those from true unenhanced images as a reference. Results The dose distributions obtained from both series of virtual unenhanced images were almost equivalent to that from the true unenhanced images, whereas the dose distribution obtained from the enhanced images indicated increased beam attenuation caused by the high attenuation characteristics of iodine. Compared to the reference dose distribution from

  11. Feasibility of labile Zn phytoextraction using enhanced tobacco and sunflower: results of five- and one-year field-scale experiments in Switzerland.

    PubMed

    Herzig, Rolf; Nehnevajova, Erika; Pfistner, Charlotte; Schwitzguebel, Jean-Paul; Ricci, Arturo; Keller, Charles

    2014-01-01

    Phytoextraction with somaclonal variants of tobacco and sunflower mutant lines (non-GMs) with enhanced metal uptake and tolerance can be a sustainable alternative to conventional destructive decontamination methods, especially for stripping bioavailable zinc excess in topsoil. The overall results of a 5-year time series experiment at field scale in north-eastern Switzerland confirm that the labile Zn pool in soil can be lowered by 45-70%, whereas subplots without phytoextraction treatment maintained labile Zn concentrations. In 2011, the phytoextraction experiment site was enlarged by a factor of 3, and the labile 0.1 M NaNO3 extractable Zn concentration in the soil was reduced up to 58% one period after harvest. A Mass Balance Analysis confirmed soil Zn decontamination in line with plant Zn uptake. The plants partially take Zn from the non-labile pool of the totaL The sustainability of Zn phytoextraction in subplots that no longer exceed the Swiss trigger value is now assessed over time. In contrary to the phytoextraction of total soil Zn which needs a long cleaning up time, the bioavailable Zn stripping is feasible within a few years period. PMID:24933882

  12. Feasibility of Single-Input Tracer Kinetic Modeling with Continuous-Time Formalism in Liver 4-Phase Dynamic Contrast-Enhanced CT

    PubMed Central

    Lee, Sang Ho; Ryu, Yasuji; Hayano, Koichi; Yoshida, Hiroyuki

    2015-01-01

    The modeling of tracer kinetics with use of low-temporal-resolution data is of central importance for patient dose reduction in dynamic contrast-enhanced CT (DCE-CT) study. Tracer kinetic models of the liver vary according to the physiologic assumptions imposed on the model, and they can substantially differ in the ways how the input for blood supply and tissue compartments are modeled. In this study, single-input flow-limited (FL), Tofts-Kety (TK), extended TK (ETK), Hayton-Brady (HB), two compartment exchange (2CX), and adiabatic approximation to the tissue homogeneity (AATH) models were applied to the analysis of liver 4-phase DCE-CT data with fully continuous-time parameter formulation, including the bolus arrival time. The bolus arrival time for the 2CX and AATH models was described by modifying the vascular transport operator theory. Initial results indicate that single-input tracer kinetic modeling is feasible for distinguishing between hepatocellular carcinoma and normal liver parenchyma. PMID:26236779

  13. Feasibility of Using Volumetric Contrast-Enhanced Ultrasound with a 3-D Transducer to Evaluate Therapeutic Response after Targeted Therapy in Rabbit Hepatic VX2 Carcinoma.

    PubMed

    Kim, Jeehyun; Kim, Jung Hoon; Yoon, Soon Ho; Choi, Won Seok; Kim, Young Jae; Han, Joon Koo; Choi, Byung-Ihn

    2015-12-01

    The aim of this study was to assess the feasibility of using dynamic contrast-enhanced ultrasound (DCE-US) with a 3-D transducer to evaluate therapeutic responses to targeted therapy. Rabbits with hepatic VX2 carcinomas, divided into a treatment group (n = 22, 30 mg/kg/d sorafenib) and a control group (n = 13), were evaluated with DCE-US using 2-D and 3-D transducers and computed tomography (CT) perfusion imaging at baseline and 1 d after the first treatment. Perfusion parameters were collected, and correlations between parameters were analyzed. In the treatment group, both volumetric and 2-D DCE-US perfusion parameters, including peak intensity (33.2 ± 19.9 vs. 16.6 ± 10.7, 63.7 ± 20.0 vs. 30.1 ± 19.8), slope (15.3 ± 12.4 vs. 5.7 ± 4.5, 37.3 ± 20.4 vs. 15.7 ± 13.0) and area under the curve (AUC; 1004.1 ± 560.3 vs. 611.4 ± 421.1, 1332.2 ± 708.3 vs. 670.4 ± 388.3), had significantly decreased 1 d after the first treatment (p = 0.00). In the control group, 2-D DCE-US revealed that peak intensity, time to peak and slope had significantly changed (p < 0.05); however, volumetric DCE-US revealed that peak intensity, time-intensity AUC, AUC during wash-in and AUC during wash-out had significantly changed (p = 0.00). CT perfusion imaging parameters, including blood flow, blood volume and permeability of the capillary vessel surface, had significantly decreased in the treatment group (p = 0.00); however, in the control group, peak intensity and blood volume had significantly increased (p = 0.00). It is feasible to use DCE-US with a 3-D transducer to predict early therapeutic response after targeted therapy because perfusion parameters, including peak intensity, slope and AUC, significantly decreased, which is similar to the trend observed for 2-D DCE-US and CT perfusion imaging parameters. PMID:26365926

  14. Mamma Mia: A Feasibility Study of a Web-Based Intervention to Reduce the Risk of Postpartum Depression and Enhance Subjective Well-Being

    PubMed Central

    2013-01-01

    Background Currently, 10-15% of women giving birth suffer from symptoms of postpartum depression. Due to a lack of knowledge of this condition and the stigma associated with it, as well as few treatment options, a large proportion of postpartum women with depression remain untreated. Internet-based interventions have been found effective in treating depression, anxiety, phobias, and addictions. Hence, we developed such program (“Mamma Mia”) with the aim of reducing the risk for postpartum depression and enhance subjective well-being. Mamma Mia is based on positive psychology, metacognitive therapy, and couples therapy. It starts in gestational week 22, and lasts until 6 months after birth. During pregnancy, Mamma Mia is delivered weekly (every Monday). After birth, Mamma Mia is delivered three times per week for six weeks. The remaining weeks, the program is delivered more sporadically. In total, Mamma Mia consists of 44 sessions. The program is individualized, interactive, and tunneled (ie, the user is guided through the program in a pre-determined manner). Objective The purpose of the present study was to pilot test the intervention in order to assess the feasibility and acceptance among program users. Methods The present paper reports a feasibility study that combined quantitative survey data with semi-structured interviews. Participants (N=103) were recruited via hospitals, well-baby clinics, and Facebook. Due to time constraint in completing the current study, our results were based on participation in one of the two phases: pregnancy or maternity. Participants in the pregnancy phase were surveyed 4 and 8 weeks after intervention enrollment, and participants in the postnatal phase were surveyed 2 and 4 weeks after intervention enrollment. The survey assessed perceived usefulness, ease-of-use, credibility, and unobtrusiveness. All measures were filled in by participants at both measurement occasions. Data were analyzed by running descriptives and

  15. The 2005 Project Progress Report for 1987-099-00 Dworshak Kokanee Population and Entrainment Assessment (contract # 16791) is attached to project 1987-099-00, contract # 26850. [POINTER

    SciTech Connect

    2008-12-18

    During this contract, we continued testing underwater strobe lights to determine their effectiveness at repelling kokanee Oncorhynchus nerka away from Dworshak Dam. We tested one set of nine strobe lights flashing at a rate of 360 flashes/min in front of turbine 3 while operating at higher discharges than previously tested. The density and distribution of fish, (thought to be mostly kokanee), were monitored with a split-beam echo sounder. We then compared fish counts and densities during nights when the lights were flashing to counts and densities during adjacent nights without the lights on. On five nights between January 31 and February 28, 2006, when no lights were present, fish counts near turbine 3 averaged eight fish and densities averaged 91 fish/ha. When strobe lights were turned on during five adjacent nights during the same period, mean counts dropped to four fish and densities dropped to 35 fish/ha. The decline in counts (49%) was not statistically significant (p = 0.182), but decline in densities (62%) was significant (p = 0.049). There appeared to be no tendency for fish to habituate to the lights during the night. Test results indicated that strobe lights were able to reduce fish densities by at least 50% in front of turbines operating at higher discharges, which would be sufficient to improve sportfish harvest. We also used split-beam hydroacoustics to monitor the kokanee population in Dworshak Reservoir during 2005. Estimated abundance of kokanee decreased from the 2004 population estimate. Based on hydroacoustic surveys, we estimated 3,011,626 kokanee (90% CI {+-} 15.2%) in Dworshak Reservoir, July 2005. This included 2,135,986 age-0 (90% CI {+-} 15.9%), 769,175 age-1 (90% CI {+-} 16.0%), and 107,465 age-2 (90% CI {+-} 15.2%). Poor survival of kokanee from age-1 to age-2 continued to keep age-2 densities below the management goal of 30-50 adults/ha. Entrainment sampling was conducted with fixed-site split-beam hydroacoustics a minimum of two days

  16. Feasibility of PRIME: A Cognitive Neuroscience-Informed Mobile App Intervention to Enhance Motivated Behavior and Improve Quality of Life in Recent Onset Schizophrenia

    PubMed Central

    Campellone, Timothy; Kim, Daniel; Truong, Brandy; Vergani, Silvia; Ward, Charlie; Vinogradov, Sophia

    2016-01-01

    Background Despite improvements in treating psychosis, schizophrenia remains a chronic and debilitating disorder that affects approximately 1% of the US population and costs society more than depression, dementia, and other medical illnesses across most of the lifespan. Improving functioning early in the course of illness could have significant implications for long-term outcome of individuals with schizophrenia. Yet, current gold-standard treatments do not lead to clinically meaningful improvements in outcome, partly due to the inherent challenges of treating a population with significant cognitive and motivational impairments. The rise of technology presents an opportunity to develop novel treatments that may circumvent the motivational and cognitive challenges observed in schizophrenia. Objective The purpose of this study was two-fold: (1) to evaluate the feasibility and acceptability of implementing a Personalized Real-Time Intervention for Motivation Enhancement (PRIME), a mobile app intervention designed to target reward-processing impairments, enhance motivation, and thereby improve quality of life in recent onset schizophrenia, and (2) evaluate the empirical benefits of using an iterative, user-centered design (UCD) process. Methods We conducted two design workshops with 15 key stakeholders, followed by a series of in-depth interviews in collaboration with IDEO, a design and innovation firm. The UCD approach ultimately resulted in the first iteration of PRIME, which was evaluated by 10 RO participants. Results from the Stage 1 participants were then used to guide the next iteration that is currently being evaluated in an ongoing RCT. Participants in both phases were encouraged to use the app daily with a minimum frequency of 1/week over a 12-week period. Results The UCD process resulted in the following feature set: (1) delivery of text message (short message service, SMS)-based motivational coaching from trained therapists, (2) individualized goal setting

  17. The Value of Intraoperative Near-Infrared Fluorescence Imaging Based on Enhanced Permeability and Retention of Indocyanine Green: Feasibility and False-Positives in Ovarian Cancer

    PubMed Central

    Peters, Alexander A. W.; de Kroon, Cor D.; Trimbos, J. Baptist M. Z.; van de Velde, Cornelis J. H.; Frangioni, John V.; Vahrmeijer, Alexander L.; Gaarenstroom, Katja N.

    2015-01-01

    Objective In ovarian cancer, two of the most important prognostic factors for survival are completeness of staging and completeness of cytoreductive surgery. Therefore, intra-operative visualization of tumor lesions is of great importance. Preclinical data already demonstrated tumor visualization in a mouse-model using near-infrared (NIR) fluorescence imaging and indocyanine green (ICG) as a result of enhanced permeability and retention (EPR). The aim of this study was to determine feasibility of intraoperative ovarian cancer metastases imaging using NIR fluorescence imaging and ICG in a clinical setting. Methods Ten patients suspected of ovarian cancer scheduled for staging or cytoreductive surgery were included. Patients received 20 mg ICG intravenously after opening the abdominal cavity. The mini-FLARE NIR fluorescence imaging system was used to detect NIR fluorescent lesions. Results 6 out of 10 patients had malignant disease of the ovary or fallopian tube, of which 2 had metastatic disease outside the pelvis. Eight metastatic lesions were detected in these 2 patients, which were all NIR fluorescent. However, 13 non-malignant lesions were also NIR fluorescent, resulting in a false-positive rate of 62%. There was no significant difference in tumor-to-background ratio between malignant and benign lesions (2.0 vs 2.0; P=0.99). Conclusions This is the first clinical trial demonstrating intraoperative detection of ovarian cancer metastases using NIR fluorescence imaging and ICG. Despite detection of all malignant lesions, a high false-positive rate was observed. Therefore, NIR fluorescence imaging using ICG based on the EPR effect is not satisfactory for the detection of ovarian cancer metastases. The need for tumor-specific intraoperative agents remains. Trial Registration ISRCTN Registry ISRCTN16945066 PMID:26110901

  18. A feasibility study of projection-based energy weighting based on a photon-counting detector in contrast-enhanced digital subtraction mammography: A simulation study

    NASA Astrophysics Data System (ADS)

    Choi, Sunghoon; Lee, Seungwan; Choi, Yu-Na; Kim, Hee-Joung

    2014-06-01

    Contrast media, such as iodine and gadolinium, are generally used in digital subtraction mammography to enhance the contrast between target and background materials. In digital subtraction mammography, where one image (with contrast medium) is subtracted from another (anatomical background) to facilitate visualization of the tumor structure, tumors can be more easily distinguished after the injection of a contrast medium. In order to have more an effective method to increase the contrast-to-noise ratio (CNR), we applied a projection-based energy-weighting method. The purpose of this study is to demonstrate the feasibility of using the projection-based energy-weighting method in digital subtraction mammography. Unlike some other previous studies, we applied the projection-based energy-weighting method to more practical mammography conditions by using the Monte Carlo method to simulate four different iodine solutions embedded in a breast phantom comprised of 50% adipose and 50% glandular tissues. We also considered an optimal tube voltage and anode/filter combination in digital iodine contrast media mammography in order to maximize the figure-of-merit (FOM). The simulated source energy was from 20 to 45 keV to prevent electronic noise and include the k-edge energy of iodine (33.2 keV). The results showed that the projection-based energy-weighting improved the CNR by factors of 1.05-1.86 compared to the conventionally integrated images. Consequently, the CNR of digital subtraction mammography images can be improved by using projection-based energy-weighting with photon-counting detectors.

  19. Feasibility and Impact of Implementing Motivational Enhancement Therapy--Cognitive Behavioral Therapy as a Substance Use Treatment Intervention in School-Based Settings

    ERIC Educational Resources Information Center

    Belur, Vinetha; Dennis, Michael L.; Ives, Melissa L.; Vincent, Robert; Muck, Randolph

    2014-01-01

    The expansion of behavioral health services to school-based health centers under the Affordable Care Act (Public Law 111-148) presents an opportunity to improve access to substance use disorders treatment for youth and reduce their substance use, and emotional, health, and school problems. We explore the feasibility of implementing five to seven…

  20. Lake Roosevelt Fisheries Monitoring Program; Artificial Imprinting of Lake Roosevelt Kokanee Salmon (Oncorhynchus Nerka) with Synthetic Chemicals: Measurement of Thyroxine Content as an Indicator of the Sensitive Period for Imprinting to Olfactory Cues; 1992 Supplement Report.

    SciTech Connect

    Scholz, Allan T.; White, Ronald J.; Tilson, Mary Beth

    1993-09-01

    In 1991, we initiated studies to determine the critical period for thyroxine-induced olfactory imprinting in kokanee salmon. In our preliminary investigation we found that thyroxine [T{sub 4}] levels of Lake Whatcom stock, 1990 year class, kokanee were relatively high in eggs and alevins as compared to post-swimup fry, and peaked at hatch and swimup. Here we report on follow-up studies conducted in 1992 designed to determine if our initial results could be replicated. Additionally, in 1992, we initiated experiments to determine if kokanee could be imprinted to synthetic chemicals--morpholine and phenethyl alcohol--at different life stages. In 1991, whole body thyroxine content [T{sub 4}] was measured in 460 Lake Whatcom stock kokanee and 480 Lake Pend Orielle (Cabinet Gorge) stock kokanee to indicate the critical period for imprinting. Lots of 20 kokanee eggs, alevins and fry from both stocks, reared at the Spokane Tribal hatchery, were collected at weekly intervals from November 1991 to August 1992 and assayed for T{sub 4} content by radioimmunoassay. T{sub 4} levels were monitored in Lake Whatcom stock, 1991 year class fish, from eyed egg (33 days post-fertilization) to fry (248 days post-fertilization) stages. T{sub 4} concentration ({+-} SEM) in eggs was 6.7 {+-} 1.3 rig/g body weight. T{sub 4} peaked on the day of hatch at 13.1 {+-} 2.5 ng/g body weight, then declined to 10.3 {+-} 1.1 ng/g body weight in recently post-hatch alevins. T{sub 4} peaked again at 22.1 {+-} 5.2 ng/g body weight during swimup, then steadily decreased to about 1.0 ng/g body weight in 176-248 day old fry. T{sub 4} levels were monitored in Lake Pend Orielle stock, 1991 year class, fish from the day of fertilization (day 0) to 225 days post-fertilization. T{sub 4} content of eggs was 9.5 {+-} 1.7 ng/g body weight and peaked on the day of hatch (day 53 post-fertilization) at 24.2 {+-} 4.5 ng/g body weight. After declining to 13.0 {+-} 2.9 ng/g body weight on day 81 post-fertilization, T

  1. "Is Your Man Stepping Out?" An Online Pilot Study to Evaluate Acceptability of a Guide-Enhanced HIV Prevention Soap Opera Video Series and Feasibility of Recruitment by Facebook Advertising.

    PubMed

    Jones, Rachel; Lacroix, Lorraine J; Nolte, Kerry

    2015-01-01

    Love, Sex, and Choices (LSC) is a 12-episode soap opera video series developed to reduce HIV risk among at-risk Black urban women. We added a video guide commentator to offer insights at critical dramatic moments. An online pilot study evaluated acceptability of the Guide-Enhanced LSC (GELSC) and feasibility of Facebook advertising, streaming to smartphones, and retention. Facebook ads targeted high-HIV-prevalence areas. In 30 days, Facebook ads generated 230 screening interviews: 84 were high risk, 40 watched GELSC, and 39 followed up at 30 days. Recruitment of high-risk participants was 10 per week, compared to seven per week in previous field recruitment. Half the sample was Black; 12% were Latina. Findings suggest GELSC influenced sex scripts and behaviors. It was feasible to recruit young urban women from a large geographic area via Facebook and to retain the sample. We extended the reach to at-risk women by streaming to mobile devices. PMID:26066692

  2. The feasibility of in vivo quantification of bone-gadolinium in humans by prompt gamma neutron activation analysis (PGNAA) following gadolinium-based contrast-enhanced MRI

    NASA Astrophysics Data System (ADS)

    Mostafaei, F.; McNeill, F. E.; Chettle, D. R.; Noseworthy, M. D.; Prestwich, W. V.

    2015-11-01

    The feasibility of using a 238Pu/Be-based in vivo prompt γ-ray neutron activation analysis (IVNAA) system, previously successfully used for measurements of muscle, for the detection of gadolinium (Gd) in bone was presented. Gd is extensively used in contrast agents in MR imaging. We present phantom measurement data for the measurement of Gd in the tibia. Gd has seven naturally occurring isotopes, of which two have extremely large neutron capture cross sections; 155Gd (14.8% natural abundance (NA), σ= 60,900 barns) and 157Gd (15.65% NA, σ= 254,000 barns). Our previous work focused on muscle but this only informs about the short term kinetics of Gd. We studied the possibility of measuring bone, as it may be a long term storage site for Gd. A human simulating bone phantom set was developed. The phantoms were doped with seven concentrations of Gd of concentrations 0.0, 25, 50, 75, 100, 120 and 150 ppm. Additional elements important for neutron activation analysis, Na, Cl and Ca, were also included to create an overall elemental composition consistent with Reference Man. The overall conclusion is that the potential application of this Pu-Be-based prompt in vivo NAA for the monitoring of the storage and retention of Gd in bone is not feasible.

  3. Sentinel Node Biopsy for the Head and Neck Using Contrast-Enhanced Ultrasonography Combined with Indocyanine Green Fluorescence in Animal Models: A Feasibility Study

    PubMed Central

    Sato, Dai; Ikeda, Tetsuya; Matsumoto, Yoshifumi; Moro, Yorihisa; Kimura, Toru; Hamanoue, Yasuhiro; Nakamura, Takehiro; Yamauchi, Koichi; Saito, Koichiro; Sugasawa, Masashi; Kohno, Naoyuki

    2015-01-01

    Background Sentinel node navigation surgery is gaining popularity in oral cancer. We assessed application of sentinel lymph node navigation surgery to pharyngeal and laryngeal cancers by evaluating the combination of contrast-enhanced ultrasonography and indocyanine green fluorescence in animal models. Methods This was a prospective, nonrandomized, experimental study in rabbit and swine animal models. A mixture of indocyanine green and Sonazoid was used as the tracer. The tracer mixture was injected into the tongue, larynx, or pharynx. The sentinel lymph nodes were identified transcutaneously by infra-red camera and contrast-enhanced ultrasonography. Detection time and extraction time of the sentinel lymph nodes were measured. The safety of the tracer mixture in terms of mucosal reaction was evaluated macroscopically and microscopically. Results Sentinel lymph nodes were detected transcutaneously by contrast-enhanced ultrasonography alone. The number of sentinel lymph nodes detected was one or two. Despite observation of contrast enhancement of Sonazoid for at least 90 minutes, the number of sentinel lymph nodes detected did not change. The average extraction time of sentinel lymph nodes was 4.8 minutes. Indocyanine green fluorescence offered visual information during lymph node biopsy. The safety of the tracer was confirmed by absence of laryngeal edema both macro and microscopically. Conclusions The combination method of indocyanine green fluorescence and contrast-enhanced ultrasonography for detecting sentinel lymph nodes during surgery for head and neck cancer seems promising, especially for pharyngeal and laryngeal cancer. Further clinical studies to confirm this are warranted. PMID:26161800

  4. Predictive model for contrast-enhanced ultrasound of the breast: Is it feasible in malignant risk assessment of breast imaging reporting and data system 4 lesions?

    PubMed Central

    Luo, Jun; Chen, Ji-Dong; Chen, Qing; Yue, Lin-Xian; Zhou, Guo; Lan, Cheng; Li, Yi; Wu, Chi-Hua; Lu, Jing-Qiao

    2016-01-01

    AIM: To build and evaluate predictive models for contrast-enhanced ultrasound (CEUS) of the breast to distinguish between benign and malignant lesions. METHODS: A total of 235 breast imaging reporting and data system (BI-RADS) 4 solid breast lesions were imaged via CEUS before core needle biopsy or surgical resection. CEUS results were analyzed on 10 enhancing patterns to evaluate diagnostic performance of three benign and three malignant CEUS models, with pathological results used as the gold standard. A logistic regression model was developed basing on the CEUS results, and then evaluated with receiver operating curve (ROC). RESULTS: Except in cases of enhanced homogeneity, the rest of the 9 enhancement appearances were statistically significant (P < 0.05). These 9 enhancement patterns were selected in the final step of the logistic regression analysis, with diagnostic sensitivity and specificity of 84.4% and 82.7%, respectively, and the area under the ROC curve of 0.911. Diagnostic sensitivity, specificity, and accuracy of the malignant vs benign CEUS models were 84.38%, 87.77%, 86.38% and 86.46%, 81.29% and 83.40%, respectively. CONCLUSION: The breast CEUS models can predict risk of malignant breast lesions more accurately, decrease false-positive biopsy, and provide accurate BI-RADS classification. PMID:27358688

  5. A Pilot Study of the Feasibility and Efficacy of the Strategies to Enhance Positive Parenting (STEPP) Program for Single Mothers of Children with ADHD

    ERIC Educational Resources Information Center

    Chacko, Anil; Wymbs, Brian T.; Flammer-Rivera, Lizette M.; Pelham, William E.; Walker, Kathryn S.; Arnold, Fran W.; Visweswaraiah, Hema; Swanger-Gagne, Michelle; Girio, Erin L.; Pirvics, Lauma L.; Herbst, Laura

    2008-01-01

    Objective: The Strategies to Enhance Positive Parenting (STEPP) program was developed to address putative factors related to poor engagement in and outcomes following traditional behavioral parent training (BPT) for single mothers of children diagnosed with ADHD. Method: Twelve single mothers of children with ADHD were enrolled in an initial…

  6. Detection of lymph node metastases with ultrasmall superparamagnetic iron oxide (USPIO)-enhanced magnetic resonance imaging in oesophageal cancer: a feasibility study

    PubMed Central

    van der Jagt, E.J.; van Westreenen, H.L.; van Dullemen, H.M.; Kappert, P.; Groen, H.; Sietsma, J.; Oudkerk, M.; Plukker, J.Th.M.; van Dam, G.M.

    2009-01-01

    Abstract Aim: In this feasibility study we investigated whether magnetic resonance imaging (MRI) with ultrasmall superparamagnetic iron oxide (USPIO) can be used to identify regional and distant lymph nodes, including mediastinal and celiac lymph node metastases in patients with oesophageal cancer. Patients and methods: Ten patients with a potentially curative resectable cancer of the oesophagus were eligible for this study. All patients included in the study had positive lymph nodes on conventional staging (including endoscopic ultrasound, computed tomography and fluorodeoxyglucose-positron emission tomography). Nine patients underwent MRI + USPIO before surgery. Results were restricted to those patients who had both MRI + USPIO and histological examination. Results were compared with conventional staging and histopathologic findings. Results: One patient was excluded due to expired study time. Five out of 9 patients underwent an exploration; in 1 patient prior to surgery MRI + USPIO diagnosed liver metastases and in 3 patients an oesophageal resection was performed. USPIO uptake in mediastinal lymph nodes was seen in 6 out of 9 patients; in 3 patients non-malignant nodes were not visible. In total, 9 lymph node stations (of 6 patients) were separately analysed; 7 lymph node stations were assessed as positive (N1) on MRI+USPIO compared with 9 by conventional staging. According to histology findings, there was one false-positive and one false-negative result in MRI + USPIO. Also, conventional staging modalities had one false-positive and one false-negative result. MRI + USPIO had surplus value in one patient. Not all lymph node stations could be compared due to unforeseen explorations. No adverse effects occurred after USPIO infusion. Conclusion: MRI+USPIO identified the majority of mediastinal and celiac (suspect) lymph nodes in 9 patients with oesophageal cancer. MRI+USPIO could have an additional value in loco-regional staging; however, more

  7. A feasibility study to determine the potential of in vivo detection of gadolinium by x-ray fluorescence (XRF) following gadolinium-based contrast-enhanced MRI.

    PubMed

    Mostafaei, F; McNeill, F E; Chettle, D R; Noseworthy, M D

    2015-01-01

    The feasibility of using a (109)Cd γ-ray induced K x-ray fluorescence (K-XRF) system for the in vivo detection of gadolinium (Gd) in bone has been investigated. The K-XRF bone measurement system employs an array of four detectors, and is normally used for the non-invasive study of bone lead levels. The system was used to measure bone simulating phantoms doped with varying levels of gadolinium and fixed amounts of sodium (Na), chlorine (Cl) and calcium (Ca). The detection limits for bare bone phantoms, using a source of activity 0.17 GBq, were determined to be 3.9 ppm and 6.5 ppm (µg Gd per gram phantom) for the Kα1 and Kα2 Gd x-ray peaks, respectively. This leads to an overall detection limit of 3.3 ppm (µg Gd per gram phantom). Layers of plastic were used to simulate overlying soft tissue and this permitted prediction of a detection limit, using the current strength of our radioisotope source, of 6.1 ppm to 8.6 ppm (µg Gd per gram phantom) for fingers with 2-4 mm of overlying tissue. With a new source of activity 5 GBq, we predict that this system could achieve a detection limit of 4-5.6 µg Gd g(-1) Ca. This is within the range of levels (2-30 µg Gd g(-1) Ca) previously found in the bone of patients receiving Gd based contrast imaging agents. The technique is promising and warrants further investigation. PMID:25501799

  8. SU-E-J-182: A Feasibility Study Evaluating Automatic Identification of Gross Tumor Volume for Breast Cancer Radiotherapy Using Dynamic Contrast-Enhanced MR Imaging

    SciTech Connect

    Wang, C; Horton, J; Yin, F; Blitzblau, R; Palta, M; Chang, Z

    2014-06-01

    Purpose: To develop a computerized pharmacokinetic model-free Gross Tumor Volume (GTV) segmentation method based on dynamic contrastenhanced MRI (DCE-MRI) data that can improve physician GTV contouring efficiency. Methods: 12 patients with biopsy-proven early stage breast cancer with post-contrast enhanced DCE-MRI images were analyzed in this study. A fuzzy c-means (FCM) clustering-based method was applied to segment 3D GTV from pre-operative DCE-MRI data. A region of interest (ROI) is selected by a clinician/physicist, and the normalized signal evolution curves were calculated by dividing the signal intensity enhancement value at each voxel by the pre-contrast signal intensity value at the corresponding voxel. Three semi-quantitative metrics were analyzed based on normalized signal evolution curves: initial Area Under signal evolution Curve (iAUC), Immediate Enhancement Ratio (IER), and Variance of Enhancement Slope (VES). The FCM algorithm wass applied to partition ROI voxels into GTV voxels and non-GTV voxels by using three analyzed metrics. The partition map for the smaller cluster is then generated and binarized with an automatically calculated threshold. To reduce spurious structures resulting from background, a labeling operation was performed to keep the largest three-dimensional connected component as the identified target. Basic morphological operations including hole-filling and spur removal were useutilized to improve the target smoothness. Each segmented GTV was compared to that drawn by experienced radiation oncologists. An agreement index was proposed to quantify the overlap between the GTVs identified using two approaches and a thershold value of 0.4 is regarded as acceptable. Results: The GTVs identified by the proposed method were overlapped with the ones drawn by radiation oncologists in all cases, and in 10 out of 12 cases, the agreement indices were above the threshold of 0.4. Conclusion: The proposed automatic segmentation method was shown to

  9. An Evaluation of the Feasibility of Combining Carbon Dioxide Flooding Technologies with Microbial Enhanced Oil Recovery Technologies in Order To Sequester Carbon Dioxide

    SciTech Connect

    Todd French; Lew Brown; Rafael Hernandez; Magan Green; Lynn Prewitt; Terry Coggins

    2009-08-19

    The need for more energy as our population grows results in an increase in the amount of CO2 introduced into the atmosphere. The effect of this introduction is currently debated intensely as to the severity of the effect of this. The bjective of this investigation was to determine if the production of more energy (i.e. petroleum) and the sequestration of CO2 could be coupled into one process. Carbon dioxide flooding is a well-established technique that introduces Compressed CO2 into a subsurface oil-bearing formation to aide in liquefying harder to extract petroleum and enhancing its mobility towards the production wells.

  10. Decision tree analysis as a supplementary tool to enhance histomorphological differentiation when distinguishing human from non-human cranial bone in both burnt and unburnt states: A feasibility study.

    PubMed

    Simmons, T; Goodburn, B; Singhrao, S K

    2016-01-01

    This feasibility study was undertaken to describe and record the histological characteristics of burnt and unburnt cranial bone fragments from human and non-human bones. Reference series of fully mineralized, transverse sections of cranial bone, from all variables and specimen states, were prepared by manual cutting and semi-automated grinding and polishing methods. A photomicrograph catalogue reflecting differences in burnt and unburnt bone from human and non-humans was recorded and qualitative analysis was performed using an established classification system based on primary bone characteristics. The histomorphology associated with human and non-human samples was, for the main part, preserved following burning at high temperature. Clearly, fibro-lamellar complex tissue subtypes, such as plexiform or laminar primary bone, were only present in non-human bones. A decision tree analysis based on histological features provided a definitive identification key for distinguishing human from non-human bone, with an accuracy of 100%. The decision tree for samples where burning was unknown was 96% accurate, and multi-step classification to taxon was possible with 100% accuracy. The results of this feasibility study strongly suggest that histology remains a viable alternative technique if fragments of cranial bone require forensic examination in both burnt and unburnt states. The decision tree analysis may provide an additional but vital tool to enhance data interpretation. Further studies are needed to assess variation in histomorphology taking into account other cranial bones, ontogeny, species and burning conditions. PMID:26130749

  11. “Is Your Man Stepping Out?” An online pilot study to evaluate acceptability of a guide-enhanced HIV prevention soap opera video series and feasibility of recruitment by Facebook© advertising

    PubMed Central

    Jones, Rachel; Lacroix, Lorraine J.; Nolte, Kerry

    2015-01-01

    Love, Sex, and Choices (LSC) is a 12-episode soap opera video series developed to reduce HIV risk among at-risk Black urban women. We added a video guide commentator to offer insights at critical dramatic moments. An online pilot study evaluated acceptability of the Guide Enhanced LSC (GELSC) and feasibility of Facebook© advertising, streaming to smartphones, and retention. Facebook© ads targeted high HIV-prevalence areas. In 30 days, Facebook© ads generated 230 screening interviews; 84 were high risk, 40 watched GELSC, and 39 followed up at 30 days. Recruitment of high-risk participants was 10 per week compared to 7 per week in previous field recruitment. Half the sample was Black; 12% were Latina. Findings suggest GELSC influenced sex scripts and behaviors. It was feasible to recruit young urban women from a large geographic area via Facebook© and to retain the sample. We extended the reach to at-risk women by streaming to mobile devices. PMID:26066692

  12. SU-E-I-45: Feasibility for Using Iodine Quantification to Assist Diagnosis in Dual Energy Contrast-Enhanced Digital Mammography

    SciTech Connect

    Hwang, Y; Lin, Y; Tsai, C; Cheung, Y

    2015-06-15

    Purpose: The objective of this study is to develop quantitative calibration between image quality indexes and iodine concentration with dual-energy (DE) contrast-enhanced digital mammography (CEDM) techniques and further serve as the assistance for diagnosis. Methods: Custom-made acrylic phantom with dimensions of 24×30 cm{sup 2} simulated breast thickness from 2 to 6 cm was used in the calibration. The phantom contained matrix of four times four holes of 3 mm deep with a diameter of 15 mm for filling contrast agent with area density ranged from 0.1 to 10 mg/cm{sup 2}. All the image acquisitions were performed on a full-field digital mammography system (Senographe Essential, GE) with dual energy acquisitions. Mean pixel value (MPV), and contrast-to-noise ratio (CNR) were used for evaluating the relationship between image quality indexes and iodine concentration. Iodine map and CNR map could further be constructed with these calibration curves applied pixel by pixel utilized MATLAB software. Minimum iodine concentration could also be calculated with the visibility threshold of CNR=5 according the Rose model. Results: When evaluating the DE subtraction images, MPV increased linearly as the iodine concentration increased with all the phantom thickness surveyed (R{sup 2} between 0.989 and 0.992). Lesions with increased iodine uptake could thus be enhanced in the color-encoded iodine maps, and the mean iodine concentration could be obtained through the ROI measurements. As for investigating CNR performance, linear relationships were also shown between the iodine concentration and CNR (R{sup 2} between 0.983 and 0.990). Minimum iodine area density of 1.45, 1.73, 1.80, 1.73 and 1.72 mg/cm{sup 2} for phantom thickness of 2, 3, 4, 5, 6 cm were calculated based on Rose’s visualization criteria. Conclusion: Quantitative calibration between image quality indexes and iodine concentrations may further serving as the assistance for analyzing contrast enhancement for patient

  13. Fluorine doping: a feasible solution to enhancing the conductivity of high-resistance wide bandgap Mg0.51Zn0.49O active components

    PubMed Central

    Liu, Lishu; Mei, Zengxia; Hou, Yaonan; Liang, Huili; Azarov, Alexander; Venkatachalapathy, Vishnukanthan; Kuznetsov, Andrej; Du, Xiaolong

    2015-01-01

    N-type doping of high-resistance wide bandgap semiconductors, wurtzite high-Mg-content MgxZn1–xO for instance, has always been a fundamental application-motivated research issue. Herein, we report a solution to enhancing the conductivity of high-resistance Mg0.51Zn0.49O active components, which has been reliably achieved by fluorine doping via radio-frequency plasma assisted molecular beam epitaxial growth. Fluorine dopants were demonstrated to be effective donors in Mg0.51Zn0.49O single crystal film having a solar-blind 4.43 eV bandgap, with an average concentration of 1.0 × 1019 F/cm3.The dramatically increased carrier concentration (2.85 × 1017 cm−3 vs ~1014 cm−3) and decreased resistivity (129 Ω · cm vs ~106 Ω cm) indicate that the electrical properties of semi-insulating Mg0.51Zn0.49O film can be delicately regulated by F doping. Interestingly, two donor levels (17 meV and 74 meV) associated with F were revealed by temperature-dependent Hall measurements. A Schottky type metal-semiconductor-metal ultraviolet photodetector manifests a remarkably enhanced photocurrent, two orders of magnitude higher than that of the undoped counterpart. The responsivity is greatly enhanced from 0.34 mA/W to 52 mA/W under 10 V bias. The detectivity increases from 1.89 × 109 cm Hz1/2/W to 3.58 × 1010 cm Hz1/2/W under 10 V bias at room temperature.These results exhibit F doping serves as a promising pathway for improving the performance of high-Mg-content MgxZn1-xO-based devices. PMID:26489958

  14. Fluorine doping: a feasible solution to enhancing the conductivity of high-resistance wide bandgap Mg0.51Zn0.49O active components.

    PubMed

    Liu, Lishu; Mei, Zengxia; Hou, Yaonan; Liang, Huili; Azarov, Alexander; Venkatachalapathy, Vishnukanthan; Kuznetsov, Andrej; Du, Xiaolong

    2015-01-01

    N-type doping of high-resistance wide bandgap semiconductors, wurtzite high-Mg-content MgxZn1-xO for instance, has always been a fundamental application-motivated research issue. Herein, we report a solution to enhancing the conductivity of high-resistance Mg0.51Zn0.49O active components, which has been reliably achieved by fluorine doping via radio-frequency plasma assisted molecular beam epitaxial growth. Fluorine dopants were demonstrated to be effective donors in Mg0.51Zn0.49O single crystal film having a solar-blind 4.43 eV bandgap, with an average concentration of 1.0 × 10(19) F/cm(3).The dramatically increased carrier concentration (2.85 × 10(17) cm(-3) vs ~10(14) cm(-3)) and decreased resistivity (129 Ω · cm vs ~10(6) Ω cm) indicate that the electrical properties of semi-insulating Mg0.51Zn0.49O film can be delicately regulated by F doping. Interestingly, two donor levels (17 meV and 74 meV) associated with F were revealed by temperature-dependent Hall measurements. A Schottky type metal-semiconductor-metal ultraviolet photodetector manifests a remarkably enhanced photocurrent, two orders of magnitude higher than that of the undoped counterpart. The responsivity is greatly enhanced from 0.34 mA/W to 52 mA/W under 10 V bias. The detectivity increases from 1.89 × 10(9) cm Hz(1/2)/W to 3.58 × 10(10) cm Hz(1/2)/W under 10 V bias at room temperature.These results exhibit F doping serves as a promising pathway for improving the performance of high-Mg-content MgxZn1-xO-based devices. PMID:26489958

  15. Fluorine doping: a feasible solution to enhancing the conductivity of high-resistance wide bandgap Mg0.51Zn0.49O active components

    NASA Astrophysics Data System (ADS)

    Liu, Lishu; Mei, Zengxia; Hou, Yaonan; Liang, Huili; Azarov, Alexander; Venkatachalapathy, Vishnukanthan; Kuznetsov, Andrej; Du, Xiaolong

    2015-10-01

    N-type doping of high-resistance wide bandgap semiconductors, wurtzite high-Mg-content MgxZn1-xO for instance, has always been a fundamental application-motivated research issue. Herein, we report a solution to enhancing the conductivity of high-resistance Mg0.51Zn0.49O active components, which has been reliably achieved by fluorine doping via radio-frequency plasma assisted molecular beam epitaxial growth. Fluorine dopants were demonstrated to be effective donors in Mg0.51Zn0.49O single crystal film having a solar-blind 4.43 eV bandgap, with an average concentration of 1.0 × 1019 F/cm3.The dramatically increased carrier concentration (2.85 × 1017 cm-3 vs ~1014 cm-3) and decreased resistivity (129 Ω · cm vs ~106 Ω cm) indicate that the electrical properties of semi-insulating Mg0.51Zn0.49O film can be delicately regulated by F doping. Interestingly, two donor levels (17 meV and 74 meV) associated with F were revealed by temperature-dependent Hall measurements. A Schottky type metal-semiconductor-metal ultraviolet photodetector manifests a remarkably enhanced photocurrent, two orders of magnitude higher than that of the undoped counterpart. The responsivity is greatly enhanced from 0.34 mA/W to 52 mA/W under 10 V bias. The detectivity increases from 1.89 × 109 cm Hz1/2/W to 3.58 × 1010 cm Hz1/2/W under 10 V bias at room temperature.These results exhibit F doping serves as a promising pathway for improving the performance of high-Mg-content MgxZn1-xO-based devices.

  16. mobile Digital Access to a Web-enhanced Network (mDAWN): Assessing the Feasibility of Mobile Health Tools for Self-Management of Type-2 Diabetes

    PubMed Central

    Ho, Kendall; Newton, Lana; Boothe, Allison; Novak-Lauscher, Helen

    2015-01-01

    The mobile Digital Access to a Web-enhanced Network (mDAWN) program was implemented as an online, mobile self-management system to support patients with type-2 diabetes and their informal caregivers. Patients used wireless physiological sensors, received text messages, and had access to a secure web platform with health resources and semi-facilitated discussion forum. Outcomes were evaluated using (1) pre and post self-reported health behavior measures, (2) physiological outcomes, (3) program cost, and (4) in-depth participant interviews. The group had significantly decreased health distress, HbA1c levels, and systolic blood pressure. Participants largely saw the mDAWN as providing good value for the costs involved and found the program to be empowering in gaining control over their diabetes. mHealth programs have the potential to improve clinical outcomes through cost effective patient-led care for chronic illness. Further evaluation needs to examine integration of similar mHealth programs into the patient-physician relationship. PMID:26958197

  17. Assessing the Feasibility and Risks of Using Wave-Driven Upwelling Pumps to Enhance the Biological Sequestration of Carbon in Open Oceans

    NASA Astrophysics Data System (ADS)

    White, A.; Bjorkman, K.; Grabowski, E.; Letelier, R. M.; Poulos, S.; Watkins, B.; Karl, D. M.

    2008-12-01

    In 1976, John D. Isaacs proposed to use wave energy to pump cold and nutrient-rich deep water into the sunlit surface layers. The motivation for this endeavor has taken many forms over the years, from energy production to fueling aquaculture to the more recent suggestion that artificial upwelling could be used to stimulate primary productivity and anthropogenic carbon sequestration in oligotrophic regions of the ocean. However, the potential for biological carbon sequestration in response to upwelling will depend on the concentration of nutrients relative to that of dissolved inorganic carbon in the water being upwelled and on the response of the marine microbial assemblage to this nutrient enrichment. In June 2008, we tested a commercially available wave pump in the vicinity of Station ALOHA, north of Oahu, Hawaii in order to assess the logistics of at-sea deployment and the survivability of the equipment in the open ocean. Our engineering test was also designed to evaluate a recently published hypothesis (Karl and Letelier, 2008, Marine Ecology Progress Series) that upwelling of water containing excess phosphate relative to nitrogen compared to the canonical "Redfield" molar ratio of 16N:1P, would generate a two-phased phytoplankton bloom and enhance carbon sequestration. In this presentation, we analyze the results of this field test within the context of pelagic biogeochemical cycles. Furthermore, we discuss the deployment of a 300m wave pump, efforts to sample a biochemical response, the engineering challenges faced and the practical and ethical implications of these results for future experiments aimed at stimulating the growth of phytoplankton in oligotrophic regions.

  18. Educating Mental Health Clinicians About Sensory Modulation to Enhance Clinical Practice in a Youth Acute Inpatient Mental Health Unit: A Feasibility Study.

    PubMed

    Blackburn, Julie; McKenna, Brian; Jackson, Brian; Hitch, Danielle; Benitez, Jessica; McLennan, Cathy; Furness, Trentham

    2016-07-01

    There is an emergence of literature describing effective sensory modulation (SM) interventions to de-escalate violence and aggression among mental health inpatients. However, the evidence is limited to adult settings, with the effect of SM in youth acute settings unknown. Yet, before SM may be used as a de-escalation intervention in youth acute settings, multidisciplinary staff need to be educated about and supported in the clinical application of SM. In the current study, an online SM education package was developed to assist mental health staff understand SM. This was blended with action learning sets (ALS), small group experiential opportunities consisting staff and consumers to learn about SM resources, and the support of SM trained nurses. The aims of the study were to evaluate the effectiveness of this SM education intervention in (a) transferring knowledge of SM to staff, and (b) translating this knowledge into practice in a youth acute inpatient mental health unit. A mixed methods research design with an 11-item pre- and post-education questionnaire was used along with three-month follow-up focus groups. The SM education improved understanding about SM (all 11-items p ≤ 0.004, r ≥ 0.47). Three-months after SM education, four themes evident in the focus group data emerged about the practice and process of SM; (1) translating of learning into practice, (2) SM in practice, (3) perceptions of SM benefits, and (4) limitations of SM. A blended SM education process enhanced clinical practice in the unit, yet participants were mindful of limitations of SM in situations of distress or escalating agitation. PMID:27253182

  19. Ecological Feasibility Studies in Restoration Decision Making

    NASA Astrophysics Data System (ADS)

    Hopfensperger, Kristine N.; Engelhardt, Katharina A. M.; Seagle, Steven W.

    2007-06-01

    The restoration of degraded systems is essential for maintaining the provision of valuable ecosystem services, including the maintenance of aesthetic values. However, restoration projects often fail to reach desired goals for a variety of ecologic, financial, and social reasons. Feasibility studies that evaluate whether a restoration effort should even be attempted can enhance restoration success by highlighting potential pitfalls and gaps in knowledge before the design phase of a restoration. Feasibility studies also can bring stakeholders together before a restoration project is designed to discuss potential disagreements. For these reasons, a feasibility study was conducted to evaluate the efficacy of restoring a tidal freshwater marsh in the Potomac River near Alexandria, Virginia. The study focused on science rather than engineering questions, and thus differed in approach from other feasibility studies that are mostly engineering driven. The authors report the framework they used to conduct a feasibility study to inform other potential restoration projects with similar goals. The seven steps of the framework encompass (1) initiation of a feasibility study, (2) compilation of existing data, (3) collection of current site information, (4) examination of case studies, (5) synthesis of information in a handbook, (6) meeting with selected stakeholders, and (7) evaluation of meeting outcomes. By conducting a feasibility study using the seven-step framework, the authors set the stage for conducting future compliance studies and enhancing the chance of a successful restoration.

  20. Ecological feasibility studies in restoration decision making.

    PubMed

    Hopfensperger, Kristine N; Engelhardt, Katharina A M; Seagle, Steven W

    2007-06-01

    The restoration of degraded systems is essential for maintaining the provision of valuable ecosystem services, including the maintenance of aesthetic values. However, restoration projects often fail to reach desired goals for a variety of ecologic, financial, and social reasons. Feasibility studies that evaluate whether a restoration effort should even be attempted can enhance restoration success by highlighting potential pitfalls and gaps in knowledge before the design phase of a restoration. Feasibility studies also can bring stakeholders together before a restoration project is designed to discuss potential disagreements. For these reasons, a feasibility study was conducted to evaluate the efficacy of restoring a tidal freshwater marsh in the Potomac River near Alexandria, Virginia. The study focused on science rather than engineering questions, and thus differed in approach from other feasibility studies that are mostly engineering driven. The authors report the framework they used to conduct a feasibility study to inform other potential restoration projects with similar goals. The seven steps of the framework encompass (1) initiation of a feasibility study, (2) compilation of existing data, (3) collection of current site information, (4) examination of case studies, (5) synthesis of information in a handbook, (6) meeting with selected stakeholders, and (7) evaluation of meeting outcomes. By conducting a feasibility study using the seven-step framework, the authors set the stage for conducting future compliance studies and enhancing the chance of a successful restoration. PMID:17453281

  1. Feasibility Study of Using Breath Ammonia Analysis Based on Off-Axis Cavity-Enhanced Absorption Spectroscopy with External Cavity Diode Laser for Noninvasive Real-Time Diagnosis of Helicobacter Pylori.

    PubMed

    Bayrakli, Ismail; Turkmen, Aysenur; Cem Kockar, Muhammet

    2016-08-01

    The purpose of this study is to assess the feasibility of using breath ammonia analysis based on off-axis cavity-enhanced absorption spectroscopy (OA-CEAS) with an external-cavity diode laser (ECL) for noninvasive, real-time diagnosis of Helicobacter pylori (HP) infection. Analyses are performed for the breath of 15 healthy volunteers, and eight children and 19 adults with HP infection. The range of ammonia levels for healthy participants is determined to be between 178 and 610 ppb, whereas the ranges for child and adult patients with HP infection are measured to be 457-2470 ppb and 450-2990 ppb, respectively. The ammonia concentrations for patients with HP infection are significantly higher than the concentrations for healthy volunteers. However, no sharp boundary between the ammonia concentrations in the breath of patients with HP infection and healthy volunteers is observed. No correlation between breath ammonia and either body mass index (BMI) or age is found. The reported results suggest that our breath ammonia measurement system has the potential for future use in easy, noninvasive diagnosis of HP infection. PMID:27296306

  2. Feasibility for mapping cartilage t1 relaxation times in the distal metacarpus3/metatarsus3 of thoroughbred racehorses using delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC): normal cadaver study.

    PubMed

    Carstens, Ann; Kirberger, Robert M; Velleman, Mark; Dahlberg, Leif E; Fletcher, Lizelle; Lammentausta, Eveliina

    2013-01-01

    Osteoarthritis of the metacarpo/metatarsophalangeal joints is one of the major causes of poor performance in horses. Delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) may be a useful technique for noninvasively quantifying articular cartilage damage in horses. The purpose of this study was to describe dGEMRIC characteristics of the distal metacarpus3/metatarsus3 (Mc3/Mt3) articular cartilage in 20 cadaver specimens collected from normal Thoroughbred horses. For each specimen, T1 relaxation time was measured from scans acquired precontrast and at 30, 60, 120, and 180 min post intraarticular injection of Gd-DTPA(2-) (dGEMRIC series). For each scan, T1 relaxation times were calculated using five regions of interest (sites 1-5) in the cartilage. For all sites, a significant decrease in T1 relaxation times occurred between precontrast scans and 30, 60, 120, and 180 min scans of the dGEMRIC series (P < 0.0001). A significant increase in T1 relaxation times occurred between 60 and 180 min and between 120 and 180 min post Gd injection for all sites. For sites 1-4, a significant increase in T1 relaxation time occurred between 30 and 180 min postinjection (P < 0.05). Sites 1-5 differed significantly among one another for all times (P < 0.0001). Findings from this cadaver study indicated that dGEMRIC using intraarticular Gd-DTPA(2-) is a feasible technique for measuring and mapping changes in T1 relaxation times in equine metacarpo/metatarsophalangeal joint cartilage. Optimal times for postcontrast scans were 60-120 min. Future studies are needed to determine whether these findings are reproducible in live horses. PMID:23551282

  3. Micro electric propulsion feasibility

    NASA Technical Reports Server (NTRS)

    Aston, Graeme; Aston, Martha

    1992-01-01

    Miniature, 50 kg class, strategic satellites intended for extended deployment in space require an on-board propulsion capability to perform needed attitude control adjustments and drag compensation maneuvers. Even on such very small spacecraft, these orbit maintenance functions can be significant and result in a substantial propellant mass requirement. Development of advanced propulsion technology could reduce this propellant mass significantly, and thereby maximize the payload capability of these spacecraft. In addition, spacecraft maneuverability could be enhanced and/or multi-year mission lifetimes realized. These benefits cut spacecraft replacement costs, and reduce services needed to maintain the launch vehicles. For SDIO brilliant pebble spacecraft, a miniaturized hydrazine propulsion system provides both boost and divert thrust control. This type of propulsion system is highly integrated and is capable of delivering large thrust levels for short time periods. However, orbit maintenance functions such as drag make-up require only very small velocity corrections. Using the boost and/or divert thrusters for these small corrections exposes this highly integrated propulsion system to continuous on/off cycling and thereby increases the risk of system failure. Furthermore, since drag compensation velocity corrections would be orders of magnitude less than these thrusters were designed to deliver, their effective specific impulse would be expected to be lower when operated at very short pulse lengths. The net result of these effects would be a significant depletion of the on-board hydrazine propellant supply throughout the mission, and a reduced propulsion system reliability, both of which would degrade the interceptors usefulness. In addition to SDIO brilliant pebble spacecraft, comparably small spacecraft can be anticipated for other future strategic defense applications such as surveillance and communication. For such spacecraft, high capability and reliability

  4. 14-plex Feasibility Report

    SciTech Connect

    Kotongan, Victoria Hazel

    2013-06-21

    The Native Village of Unalakleet project was a feasibility study for a retrofit of a “tribally owned” three story, 14 apartment complex located in Unalakleet, Alaska. The program objective and overall goal was to create a plan for retrofitting to include current appraised value and comparable costs of new construction to determine genuine feasibility as low-income multi-family housing for tribal members.

  5. Computerized Image Analysis for Identifying Triple-Negative Breast Cancers and Differentiating Them from Other Molecular Subtypes of Breast Cancer on Dynamic Contrast-enhanced MR Images: A Feasibility Study

    PubMed Central

    Agner, Shannon C.; Rosen, Mark A.; Englander, Sarah; Tomaszewski, John E.; Feldman, Michael D.; Zhang, Paul; Mies, Carolyn; Schnall, Mitchell D.

    2014-01-01

    Purpose To determine the feasibility of using a computer-aided diagnosis (CAD) system to differentiate among triple-negative breast cancer, estrogen receptor (ER)–positive cancer, human epidermal growth factor receptor type 2 (HER2)–positive cancer, and benign fibroadenoma lesions on dynamic contrast material–enhanced (DCE) magnetic resonance (MR) images. Materials and Methods This is a retrospective study of prospectively acquired breast MR imaging data collected from an institutional review board–approved, HIPAA-compliant study between 2002 and 2007. Written informed consent was obtained from all patients. The authors collected DCE MR images from 65 women with 76 breast lesions who had been recruited into a larger study of breast MR imaging. The women had triple-negative (n = 21), ER-positive (n = 25), HER2-positive (n = 18), or fibroadenoma (n = 12) lesions. All lesions were classified as Breast Imaging Reporting and Data System category 4 or higher on the basis of previous imaging. Images were subject to quantitative feature extraction, feed-forward feature selection by means of linear discriminant analysis, and lesion classification by using a support vector machine classifier. The area under the receiver operating characteristic curve (Az) was calculated for each of five lesion classification tasks involving triple-negative breast cancers. Results For each pair-wise lesion type comparison, linear discriminant analysis helped identify the most discriminatory features, which in conjunction with a support vector machine classifier yielded an Az of 0.73 (95% confidence interval [CI]: 0.59, 0.87) for triple-negative cancer versus all non–triple-negative lesions, 0.74 (95% CI: 0.60, 0.88) for triple-negative cancer versus ER- and HER2-positive cancer, 0.77 (95% CI: 0.63, 0.91) for triple-negative versus ER-positive cancer, 0.74 (95% CI: 0.58, 0.89) for triple-negative versus HER2-positive cancer, and 0.97 (95% CI: 0.91, 1.00) for triple-negative cancer

  6. Educational Feasibility Study -- 1966.

    ERIC Educational Resources Information Center

    Hubbard, Ben C., Comp.; And Others

    By virtue of a Title III Elementary and Secondary Education Act grant, the feasibility of consolidating 7 Illinois high schools was studied. Areas of consideration were geographic characteristics, high school and elementary curriculum, and cost considerations relative to high school and elementary school buildings, curriculum, transportation,…

  7. Atmospheric rendezvous feasibility study

    NASA Technical Reports Server (NTRS)

    Schaezler, A. D.

    1972-01-01

    A study was carried out to determine the feasibility of using atmospheric rendezvous to increase the efficiency of space transportation and to determine the most effective implementation. It is concluded that atmospheric rendezvous is feasible and can be utilized in a space transportation system to reduce size of the orbiter vehicle, provide a powered landing with go-around capability for every mission, and achieve lateral range performance that exceeds requirements. A significantly lighter booster and reduced launch fuel requirements are additional benefits that can be realized with a system that includes a large subsonic airplane for recovery of the orbiter. Additional reduction in booster size is possible if the airplane is designed for recovery of the booster by towing. An airplane about the size of the C-5A is required.

  8. REP Concept Feasibility Study

    NASA Technical Reports Server (NTRS)

    Edwards, Daryl A.; Ensworth, Clinton B. F.; Goodnight, Thomas W.; Sheehe, Charles J.; Wiersma, Stephen C.; Adamsen, Paul B., II; Frank, Larry

    2004-01-01

    Radioisotope Electric Propulsion (REP) may have the potential to provide certain advantages, over conventional chemical propulsion, for outer planetary exploration involving small bodies and long term investigations for medium class missions requiring power comparable to past outer planetary exploration missions. This paper describes a study that investigates the concept s feasibility by performing a preliminary conceptual design of an REP-based spacecraft for a design reference mission. The mission utilizes a spacecraft with a radioisotope power supply less than one kilowatt while operating for a minimum of 10-years. A key element of the REP spacecraft is to ensure sustained science return by orbiting or flying in formation with selected targets. Utilizing current and impending technological advances, this study finds that at a conceptual design level a small body REP orbiter/explorer appears to be feasible for the design reference mission selected for this study.

  9. A MEDLINE feasibility study.

    PubMed Central

    McGee, J L

    1980-01-01

    A MEDLINE feasibility study was conducted with the Northeastern Consortium for Health Information (NECHI) and sponsored by the New England Regional Medical Library Service. It is based on the theory that most potential users and supporters of MEDLINE within hospitals are unaware of its usefulness and applications, and that there exists a need for expanding MEDLINE services to more hospital libraries. The purpose of the study was to provide NECHI with an evaluation of MEDLINE as a feasible service by ascertaining the need and by evaluating the usefulness, satisfaction, and costs of the system. The study demonstrated sufficient use of MEDLINE to justify implementation within NECHI and it provided useful data to determine the future of MEDLINE in each institution. It documented that utilization improved rapidly with publicity and the presence of the system within an institution, that MEDLINE can be an effective and economical complement to the traditional reference services used to support information needs in hospitals, and that more hospital libraries should be able to implement MEDLINE to their advantage once potential users and supporters have been exposed to the system. PMID:6998531

  10. Quantification of Libby Reservoir Levels Needed to Maintain or Enhance Reservoir Fisheries, 1985 Annual Report.

    SciTech Connect

    Chisholm, Ian

    1985-01-01

    The goal was to quantify seasonal water levels needed to maintain or enhance the reservoir fishery in Libby. This report summarizes data collected from July 1984 through July 1985, and, where appropriate, presents data collected since 1983. The Canada, Rexford, and Tenmile areas of the reservoir are differentially affected by drawdown. Relative changes in water volume and surface area are greatest in the Canada area and smallest in the Tenmile area. Reservoir morphology and hydraulics probably play a major role in fish distribution through their influence on water temperature. Greatest areas of habitat with optimum water temperature for Salmo spp. and kokanee occurred during the spring and fall months. Dissolved oxygen, pH and conductivity levels were not limiting during any sampling period. Habitat enhancement work was largely unsuccessful. Littoral zone vegetation plantings did not survive well, primarily the result of extreme water level fluctuations. Relative abundances of fish species varied seasonally within and between the three areas. Water temperature is thought to be the major influence in fish distribution patterns. Other factors, such as food availability and turbidity, may mitigate its influence. Sampling since 1975 illustrates a continued increase in kokanee numbers and a dramatic decline in redside shiners. Salmo spp., bull trout, and burbot abundances are relatively low while peamouth and coarsescale sucker numbers remain high. A thermal dynamics model and a trophic level components model will be used to quantify the impact of reservoir operation on the reservoir habitat, primary production, secondary production and fish populations. Particulate carbon will be used to track energy flow through trophic levels. A growth-driven population dynamics simulation model that will estimate the impacts of reservoir operation on fish population dynamics is also being considered.

  11. Crumb rubber feasibility report

    SciTech Connect

    1985-11-01

    The Cumberland County supply region generates approximately 58,000 tons of scrap tires each year, equivalent to 45,000 tons of rubber after processing. Approximately 8,000 tons per year are in concentrated locations and can be easily collected. The costs of collection for the remainder vary significantly. Given current markets, economically feasible processes (ambient technology) can reprocess approximately 65 to 75 percent of the 37,000 tons into a marketable product. A processing plant sized for this supply would process 120 tons per day, a viable plant by industry standards. The end uses for whole tires constitute a negligible market, aside from the retreader market. Crumbed rubber is the major development efforts, there are potentially large opportunities in North Carolina.

  12. Tribal Utility Feasibility Study

    SciTech Connect

    Engel, R. A.; Zoellick, J. J.

    2007-06-30

    The Schatz Energy Research Center (SERC) assisted the Yurok Tribe in investigating the feasibility of creating a permanent energy services program for the Tribe. The original purpose of the DOE grant that funded this project was to determine the feasibility of creating a full-blown Yurok Tribal electric utility to buy and sell electric power and own and maintain all electric power infrastructure on the Reservation. The original project consultant found this opportunity to be infeasible for the Tribe. When SERC took over as project consultant, we took a different approach. We explored opportunities for the Tribe to develop its own renewable energy resources for use on the Reservation and/or off-Reservation sales as a means of generating revenue for the Tribe. We also looked at ways the Tribe can provide energy services to its members and how to fund such efforts. We identified opportunities for the development of renewable energy resources and energy services on the Yurok Reservation that fall into five basic categories: • Demand-side management – This refers to efforts to reduce energy use through energy efficiency and conservation measures. • Off-grid, facility and household scale renewable energy systems – These systems can provide electricity to individual homes and Tribal facilities in areas of the Reservation that do not currently have access to the electric utility grid. • Village scale, micro-grid renewable energy systems - These are larger scale systems that can provide electricity to interconnected groups of homes and Tribal facilities in areas of the Reservation that do not have access to the conventional electric grid. This will require the development of miniature electric grids to serve these interconnected facilities. • Medium to large scale renewable energy development for sale to the grid – In areas where viable renewable energy resources exist and there is access to the conventional electric utility grid, these resources can be

  13. The MRIS feasibility study

    NASA Technical Reports Server (NTRS)

    Neece, Robert T.; Cross, Aubrey E.; Schrader, James H.

    1993-01-01

    The Microwave Reflectometer Ionization Sensor (MRIS) is an instrument being developed for use in detecting and ranging of electron density layers in the reentry plasma of a space transfer vehicle. The rationale for the selection of the Double Sideband Suppressed Carrier (DSBSC) system used in the feasibility study for the MRIS is presented. A 25 GHz single-oscillator system and a 220 GHz double-oscillator system are described. The 25 GHz system was constructed and tested in the laboratory and test results are presented. As developed, the system employs a sideband spacing of 160 MHz. Based on an estimated electromagnetic wave velocity in the plasma, a round-trip phase shift measurement accuracy of +/- 7.6 degrees was required for the desired +/- 1/2 cm distance measurement accuracy. The interaction of parallel ground and reflecting planes produces interference that prevents the basic DSBSC system from meeting the accuracy goal so a frequency modulation was added to the system to allow averaging of the measured phase deviation. With an FM deviation of +/- 1 GHz, laboratory measurements were made for distances from 5 to 61 cm tip free space. Accounting for the plasma velocity factor, 82 percent of the data were equal to or better than the desired accuracy. Based on this measured result a sideband spacing to 250 MHz could be expected to yield data approximately 96 percent within the accuracy goal.

  14. North Bethesda transitway feasibility study. Final report

    SciTech Connect

    Not Available

    1992-12-01

    The study focused on private sector financing of transit improvements between North Bethesda business and commercial areas and the Grosvenor Metrorail Station. As part of this study, an investigation was made of the feasibility of using any of a number of advanced vehicle and guideway technologies commonly referred to as People Movers in this corridor. Recognizing the potential applicability of other transit technologies such as light rail or enhanced bus service, we have designated the potential alignment as a transitway to better reflect the potential for a wide range of transit services. The body of the report refers to People Mover throughout and should be interpreted as referring to a transitway.

  15. The Feasibility of Collecting School Nurse Data.

    PubMed

    Bergren, Martha Dewey

    2016-10-01

    School nurses cite barriers to collecting comprehensive data on the care they provide. This study evaluated the feasibility of collecting school nurse data on selected child health and education outcomes. Outcome variables included school health office visits; health provider, parent, and staff communication; early dismissal; and medications administered. On an average day, the school nurses cared for 43.5 students, administered 14 medications, and averaged of 17 daily communications. Day 1 data collection times averaged 15 min or less. By Day 5, 6.6 min was needed to complete the survey. Data collection was feasible for 76% of those who elected to participate. Feasibility is enhanced by limiting the number of data points and the number of days for data collection using a data collection web interface. Data collection across large numbers of nurses and a wide range of school nurse delivery models is necessary to measure the impact of school nurse presence and interventions on child health and education outcomes. PMID:27269512

  16. Dual-Doppler Feasibility Study

    NASA Technical Reports Server (NTRS)

    Huddleston, Lisa L.

    2012-01-01

    radar geometry issues at the NWS MLB radar, such as the "cone of silence" or beam blockage. In the event of a radar outage at one of the sites, the multi-radar algorithms would provide continuing coverage of the area through use of the data from the remaining operational radar sites. There are several options to collect, edit, synthesize and display dual-Doppler data sets. These options include commercial packages available for purchase and a variety of freeware packages available from the National Center for Atmospheric Research (NCAR) for processing raw radar data. However, evaluation of the freeware packages revealed that they do not have sufficient documentation and configuration control to be certified for 45 SW use. Additionally, a TI data line must be installed/leased from the NWS MLB office and CCAFS to enable the receipt of NWS MLB raw radar data to use in the dual-Doppler synthesis. Integration of the TI data line into the Eastern Range infrastructure that will meet the security requirements necessary for 45 SW use is time-consuming and costly. Overall evaluation indicates that establishment of the dual-Doppler capability using the existing operational radar systems is desirable and feasible with no technical concerns. Installation of such a system represents a significant enhancement to forecasting capabilities at the 45 WS and at NWS MLB. However, data security and cost considerations must be evaluated in light of current budgetary constraints. In any case, gaining the dual-Doppler capability will provide opportunities for better visualization of the wind field and better forecasting of the onset of convection and severe weather events to support space launch operations at KSC and CCAFS.

  17. A feasibility study evaluating the relationship between dose and focal liver reaction in stereotactic ablative radiotherapy for liver cancer based on intensity change of Gd-EOB-DTPA-enhanced magnetic resonance images

    PubMed Central

    Jung, Sang Hoon; Yu, Jeong Il; Lim, Do Hoon; Han, Youngyih

    2016-01-01

    Purpose In order to evaluate the relationship between the dose to the liver parenchyma and focal liver reaction (FLR) after stereotactic ablative body radiotherapy (SABR), we suggest a novel method using a three-dimensional dose distribution and change in signal intensity of gadoxetate disodium-gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) hepatobiliary phase images. Materials and Methods In our method, change of the signal intensity between the pretreatment and follow-up hepatobiliary phase images of Gd-EOB-DTPA-enhanced MRI was calculated and then threshold dose (TD) for developing FLR was obtained from correlation of dose with the change of the signal intensity. For validation of the method, TDs for six patients, who had been treated for liver cancer with SABR with 45–60 Gy in 3 fractions, were calculated using the method, and we evaluated concordance between volume enclosed by isodose of TD by the method and volume identified as FLR by a physician. Results The dose to normal liver was correlated with change in signal intensity between pretreatment and follow-up MRI with a median R2 of 0.935 (range, 0.748 to 0.985). The median TD by the method was 23.5 Gy (range, 18.3 to 39.4 Gy). The median value of concordance was 84.5% (range, 44.7% to 95.9%). Conclusion Our method is capable of providing a quantitative evaluation of the relationship between dose and intensity changes on follow-up MRI, as well as determining individual TD for developing FLR. We expect our method to provide better information about the individual relationship between dose and FLR in radiotherapy for liver cancer. PMID:27104169

  18. Feasibility of Jujube peeling using novel infrared radiation heating technology

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Infrared (IR) radiation heating has a promising potential to be used as a sustainable and effective method to eliminate the use of water and chemicals in the jujube-peeling process and enhance the quality of peeled products. The objective of this study was to investigate the feasibility of use IR he...

  19. Postsecondary Student Outcomes: A Feasibility Study. Feasibility Report.

    ERIC Educational Resources Information Center

    Korb, Roslyn

    This report presents the findings from a study designed: (1) to determine the current availability and utility of student outcome statistics in the nation; and (2) to examine the feasibility and desirability of nationwide institutional reporting of student outcome data. Following an introductory section on the purposes of the report and the…

  20. Lower Sioux Wind Feasibility & Development

    SciTech Connect

    Minkel, Darin

    2012-04-01

    This report describes the process and findings of a Wind Energy Feasibility Study (Study) conducted by the Lower Sioux Indian Community (Community). The Community is evaluating the development of a wind energy project located on tribal land. The project scope was to analyze the critical issues in determining advantages and disadvantages of wind development within the Community. This analysis addresses both of the Community's wind energy development objectives: the single turbine project and the Commerical-scale multiple turbine project. The main tasks of the feasibility study are: land use and contraint analysis; wind resource evaluation; utility interconnection analysis; and project structure and economics.

  1. Hybrid deorbit motor design feasibility

    NASA Technical Reports Server (NTRS)

    Hastings, Joseph H.

    1993-01-01

    This paper addresses the feasibility of using a hybrid rocket motor to deorbit the large booster stage of the proposed NLS. A hybrid motor was of interest because it could utilize the residual low pressure Gox from the boosters main engine Lox tank. The resulting study determines that the concept would be feasible and should be given further consideration. Also, a preliminary design for a deorbit motor was proposed which would weigh much less than an equivalent hypergolic system. The hybrid deorbit concept and design has the potential of yielding a simpler cost effective system that could also be applicable to future launch systems with similar missions.

  2. Hybrid deorbit motor design feasibility

    NASA Astrophysics Data System (ADS)

    Hastings, Joseph H.

    1993-06-01

    This paper addresses the feasibility of using a hybrid rocket motor to deorbit the large booster stage of the proposed NLS. A hybrid motor was of interest because it could utilize the residual low pressure Gox from the boosters main engine Lox tank. The resulting study determines that the concept would be feasible and should be given further consideration. Also, a preliminary design for a deorbit motor was proposed which would weigh much less than an equivalent hypergolic system. The hybrid deorbit concept and design has the potential of yielding a simpler cost effective system that could also be applicable to future launch systems with similar missions.

  3. 7 CFR 4279.150 - Feasibility studies.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Feasibility studies. 4279.150 Section 4279.150... § 4279.150 Feasibility studies. A feasibility study by a qualified independent consultant may be required... affect the borrower's operations. An acceptable feasibility study should include, but not be limited...

  4. 7 CFR 4279.150 - Feasibility studies.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 15 2011-01-01 2011-01-01 false Feasibility studies. 4279.150 Section 4279.150... § 4279.150 Feasibility studies. A feasibility study by a qualified independent consultant may be required... affect the borrower's operations. An acceptable feasibility study should include, but not be limited...

  5. 7 CFR 4279.150 - Feasibility studies.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... § 4279.150 Feasibility studies. A feasibility study by a qualified independent consultant may be required... affect the borrower's operations. An acceptable feasibility study should include, but not be limited to... 7 Agriculture 15 2013-01-01 2013-01-01 false Feasibility studies. 4279.150 Section...

  6. 24 CFR 241.1010 - Feasibility letter.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...-Eligibility Requirements § 241.1010 Feasibility letter. (a) Request for study. The owner may request the Commissioner to undertake a feasibility analysis of an equity or acquisition loan, and issue a feasibility... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Feasibility letter....

  7. 24 CFR 241.1010 - Feasibility letter.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...-Eligibility Requirements § 241.1010 Feasibility letter. (a) Request for study. The owner may request the Commissioner to undertake a feasibility analysis of an equity or acquisition loan, and issue a feasibility... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Feasibility letter....

  8. 7 CFR 1980.442 - Feasibility studies.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... studies. A feasibility study by a recognized independent consultant will be required for all loans, except... a feasibility study for loans to existing businesses when the financial history of the business, the... the exception to the feasibility study for such businesses. An acceptable feasibility study...

  9. 24 CFR 241.1010 - Feasibility letter.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...-Eligibility Requirements § 241.1010 Feasibility letter. (a) Request for study. The owner may request the Commissioner to undertake a feasibility analysis of an equity or acquisition loan, and issue a feasibility... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Feasibility letter....

  10. 24 CFR 241.1010 - Feasibility letter.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...-Eligibility Requirements § 241.1010 Feasibility letter. (a) Request for study. The owner may request the Commissioner to undertake a feasibility analysis of an equity or acquisition loan, and issue a feasibility... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Feasibility letter....

  11. 7 CFR 4279.150 - Feasibility studies.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... § 4279.150 Feasibility studies. A feasibility study by a qualified independent consultant may be required... affect the borrower's operations. An acceptable feasibility study should include, but not be limited to... 7 Agriculture 15 2014-01-01 2014-01-01 false Feasibility studies. 4279.150 Section...

  12. 7 CFR 4279.150 - Feasibility studies.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... § 4279.150 Feasibility studies. A feasibility study by a qualified independent consultant may be required... affect the borrower's operations. An acceptable feasibility study should include, but not be limited to... 7 Agriculture 15 2012-01-01 2012-01-01 false Feasibility studies. 4279.150 Section...

  13. 24 CFR 241.1010 - Feasibility letter.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...-Eligibility Requirements § 241.1010 Feasibility letter. (a) Request for study. The owner may request the Commissioner to undertake a feasibility analysis of an equity or acquisition loan, and issue a feasibility... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Feasibility letter....

  14. Library Data Processing Feasibility Report.

    ERIC Educational Resources Information Center

    Mears, M. J.; And Others

    To establish the precise effects of using MARC II in West Sussex, and how it could assist the library staff were the goals of this feasibility study. It illustrates the development of the library catalog and associated systems as both realistic and practical. It indicates what kind of repercussions will be felt by the library and how it could…

  15. Computer aided cogeneration feasibility analysis

    SciTech Connect

    Anaya, D.A.; Caltenco, E.J.L.; Robles, L.F.

    1996-12-31

    A successful cogeneration system design depends of several factors, and the optimal configuration can be founded using a steam and power simulation software. The key characteristics of one of this kind of software are described below, and its application on a process plant cogeneration feasibility analysis is shown in this paper. Finally a study case is illustrated. 4 refs., 2 figs.

  16. Energy From Waste Is Feasible

    ERIC Educational Resources Information Center

    Culham, William B.

    1975-01-01

    A possible energy source is the utilization of solid waste as fuel for power production. Although this is only a partial solution to the problem, it will provide some energy while research continues. The economic feasibility of using wastes depends upon a greater amount of energy being produced than expended. (MA)

  17. Tivoli Brewery: A Feasibility Study.

    ERIC Educational Resources Information Center

    More, Combs, and Burch, Denver, CO.

    This document reports on a study made to ascertain the feasibility of preserving and restoring all or part of an existing historical site -- the "Tivoli Brewery" -- as a related and integral part of the Auraria Higher Education Center. After investigation of the building's structural integrity, the condition of electrical and mechanical systems,…

  18. Quantum telescope: feasibility and constraints.

    PubMed

    Kurek, A R; Pięta, T; Stebel, T; Pollo, A; Popowicz, A

    2016-03-15

    The quantum telescope is a recent idea aimed at beating the diffraction limit of spaceborne telescopes and possibly other distant target imaging systems. There is no agreement yet on the best setup of such devices, but some configurations have already been proposed. In this Letter we characterize the predicted performance of quantum telescopes and their possible limitations. Our extensive simulations confirm that the presented model of such instruments is feasible and the device can provide considerable gains in the angular resolution of imaging in the UV, optical, and infrared bands. We argue that it is generally possible to construct and manufacture such instruments using the latest or soon to be available technology. We refer to the latest literature to discuss the feasibility of the proposed QT system design. PMID:26977642

  19. The Feasibility of Folk Science

    PubMed Central

    Keil, Frank C.

    2010-01-01

    If folk science means individuals having well worked out mechanistic theories of the workings of the world, then it is not feasible. Lay people's explanatory understandings are remarkably coarse, full of gaps and often full of inconsistencies. Even worse, most people underestimate their own understandings. Yet, recent views suggest that formal scientists may not be so different. In spite of these limitations, science somehow works and its success offers hope for the feasibility of folk science as well. The success of science arises from the ways in which scientists learn to leverage understandings in other minds and to outsource explanatory work through sophisticated methods of deference and simplification of complex systems. Three studies ask whether analogous processes might be present not only in lay people, but also in young children and thereby form a foundation for supplementing explanatory understandings almost from the start of our first attempts to make sense of the world. PMID:20625446

  20. Conducting pilot and feasibility studies.

    PubMed

    Cope, Diane G

    2015-03-01

    Planning a well-designed research study can be tedious and laborious work. However, this process is critical and ultimately can produce valid, reliable study findings. Designing a large-scale randomized, controlled trial (RCT)-the gold standard in quantitative research-can be even more challenging. Even the most well-planned study potentially can result in issues with research procedures and design, such as recruitment, retention, or methodology. One strategy that may facilitate sound study design is the completion of a pilot or feasibility study prior to the initiation of a larger-scale trial. This article will discuss pilot and feasibility studies, their advantages and disadvantages, and implications for oncology nursing research. 
. PMID:25806886

  1. NTRE extended life feasibility assessment

    NASA Technical Reports Server (NTRS)

    1993-01-01

    Results of a feasibility analysis of a long life, reusable nuclear thermal rocket engine are presented in text and graph form. Two engine/reactor concepts are addressed: the Particle Bed Reactor (PBR) design and the Commonwealth of Independent States (CIS) concept. Engine design, integration, reliability, and safety are addressed by various members of the NTRE team from Aerojet Propulsion Division, Energopool (Russia), and Babcock & Wilcox.

  2. Lunar Analog Feasibility Study Results

    NASA Technical Reports Server (NTRS)

    Cromwell, Ronita L.; Neigut, Joe

    2009-01-01

    This slide presentation reviews a study designed to determine the feasibility of using a 9.5 deg head-up tilt bed rest model to simulate the effects of the 1/6 g load to the human body that exists on the lunar surface. The effect of different types of compression stockings, the pre-bed rest diet, and the use of a specific exercise program were reviewed for comfort, force verification and plasma volume shift

  3. Manzanita Wind Energy Feasibility Study

    SciTech Connect

    Trisha Frank

    2004-09-30

    The Manzanita Indian Reservation is located in southeastern San Diego County, California. The Tribe has long recognized that the Reservation has an abundant wind resource that could be commercially utilized to its benefit. Manzanita has explored the wind resource potential on tribal land and developed a business plan by means of this wind energy feasibility project, which enables Manzanita to make informed decisions when considering the benefits and risks of encouraging large-scale wind power development on their lands. Technical consultant to the project has been SeaWest Consulting, LLC, an established wind power consulting company. The technical scope of the project covered the full range of feasibility assessment activities from site selection through completion of a business plan for implementation. The primary objectives of this feasibility study were to: (1) document the quality and suitability of the Manzanita Reservation as a site for installation and long-term operation of a commercially viable utility-scale wind power project; and, (2) develop a comprehensive and financeable business plan.

  4. Individualized Tamoxifen Dose Escalation: Confirmation of Feasibility, Question of Utility.

    PubMed

    Hertz, Daniel L; Rae, James M

    2016-07-01

    Tamoxifen may require metabolic activation to endoxifen for efficacy in treating hormone receptor-positive breast cancer. Dose escalation in patients with low endoxifen concentrations could enhance treatment efficacy. This approach is clinically feasible, and successfully increases endoxifen concentrations; however, it is unknown whether patients benefit from individualized tamoxifen dose escalation. Clin Cancer Res; 22(13); 3121-3. ©2016 AACRSee related article by Fox et al., p. 3164. PMID:27012810

  5. Feasibility of an intelligent tutoring system for laboratory medicine.

    PubMed

    Blechner, Michael David; Sordo, Margarita

    2005-01-01

    Laboratory medicine is not adequately addressed in most medical school curricula. A review of the literature was performed to evaluate the feasibility of an intelligent tutoring system to enhance laboratory medicine training. This appraisal suggests that such a system must integrate basic science and clinical training. A system equipped with a clinical knowledgebase, in the form of an expert system, and a pathophysiology knowledgebase, in the form of multiple semantic networks, could provide such integration. PMID:16779182

  6. Chirp signal generator feasibility study

    NASA Astrophysics Data System (ADS)

    Chomiki, M.; Genauzeau, F.

    1983-03-01

    The feasibility of a signal generator with 100 microsec temporal dispersion, and 330 MHz frequency dispersion, for the ERS-1 (ESA satellite) radar altimeter, with a solid state transmitter, is demonstrated. Two surface wave dispersive filters (20 and 80 microsec dispersion) are cascaded with a frequency multiplier to give a 900 MHz output signal. The first filter receives an impulse which ensures an output signal to noise ratio 20 dB. The chirp signal output level is 0 dBm; amplitude fluctuation 2 dBcc, phase error compared with theory 10 deg rms; short term jitter 100 psec. The generator model occupies 0.5 l, and consumes 7 W.

  7. DPC loading feasibility study report

    SciTech Connect

    Dafoe, R.E.; Lopez, D.A.; Williams, K.L.

    1997-11-01

    Disposal of radioactive wastes now stored at the Idaho Chemical Processing Plant at the Idaho National Engineering and Environmental Laboratory is mandated under a ``Settlement Agreement`` between the Department of Energy and the State of Idaho. This study investigates the feasibility of using the Dry Transfer Cell facility to package waste into Dual Purpose Canisters for interim storage at the adjacent Dry Storage System comprised of an interim storage pad with NUHOMS{reg_sign} storage modules. The wastes would then be road-ready for eventual disposal in a permanent repository. The operating period for these activities is expected to be from 2015 to 2035.

  8. 12 CFR 618.8025 - Feasibility reviews.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 6 2011-01-01 2011-01-01 false Feasibility reviews. 618.8025 Section 618.8025... § 618.8025 Feasibility reviews. (a) Prior to an association offering a related service program for the... a feasibility analysis pursuant to § 618.8020. The bank review is limited to a determination...

  9. 7 CFR 1700.104 - Financial feasibility.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 11 2014-01-01 2014-01-01 false Financial feasibility. 1700.104 Section 1700.104... AGRICULTURE GENERAL INFORMATION Substantially Underserved Trust Areas § 1700.104 Financial feasibility... that contribute to a financial feasibility determination for a particular eligible program or...

  10. 12 CFR 618.8025 - Feasibility reviews.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Feasibility reviews. 618.8025 Section 618.8025... § 618.8025 Feasibility reviews. (a) Prior to an association offering a related service program for the... a feasibility analysis pursuant to § 618.8020. The bank review is limited to a determination...

  11. SYNCHEM feasibility report: Phase 1

    SciTech Connect

    Not Available

    1995-01-01

    Several Czech and US companies have entered into a development agreement for the purposes of determining the technical and economic feasibility and overall financeability of an integrated gasification combined cycle (IGCC) regional energy facility to be located adjacent to the Chemopetrol refinery in Litvinov, Czech Republic. The Project would use a feedstock comprised of coal supplied by Doly a upravny Komorany s.p. (DUK) coal mining company and mined from the Most/Litvinov area together with high sulfur residual oils from the Chemopetrol refinery. When gasified together with oxygen from an Air Products air separation plant, and based on an average yearly consumption of 2,100K metric tons per year of coal (as delivered) and 630K tonnes per year of oil, approximately 11 million normal cubic meters per day of syngas will be produced. At its current projected design capacity, when combusted in two General Electric advanced technology Frame 9FA gas turbines, the Project will produce approximately 690MW of electric power; 250 metric tons/hour of steam for process; and 135 thermal equivalent MW of district heat. The Feasibility Phase efforts described in this report indicate the real possibility for a successful and profitable IGCC Project for the Czech Republic. It is therefore incumbent upon all the Project Participants to review and evaluate the information contained herein such that a go/no-go decision can be reached by early next year.

  12. Hualapai Wind Project Feasibility Report

    SciTech Connect

    Davidson, Kevin; Randall, Mark; Isham, Tom; Horna, Marion J; Koronkiewicz, T; Simon, Rich; Matthew, Rojas; MacCourt, Doug C.; Burpo, Rob

    2012-12-20

    The Hualapai Department of Planning and Economic Development, with funding assistance from the U.S. Department of Energy, Tribal Energy Program, with the aid of six consultants has completed the four key prerequisites as follows: 1. Identify the site area for development and its suitability for construction. 2. Determine the wind resource potential for the identified site area. 3. Determine the electrical transmission and interconnection feasibility to get the electrical power produced to the marketplace. 4. Complete an initial permitting and environmental assessment to determine the feasibility for getting the project permitted. Those studies indicated a suitable wind resource and favorable conditions for permitting and construction. The permitting and environmental study did not reveal any fatal flaws. A review of the best power sale opportunities indicate southern California has the highest potential for obtaining a PPA that may make the project viable. Based on these results, the recommendation is for the Hualapai Tribal Nation to move forward with attracting a qualified wind developer to work with the Tribe to move the project into the second phase - determining the reality factors for developing a wind project. a qualified developer will bid to a utility or negotiate a PPA to make the project viable for financing.

  13. Polarized-interferometer feasibility study

    NASA Astrophysics Data System (ADS)

    Raab, F. H.

    1983-07-01

    The feasibility of using a polarized-interferometer system as a rendezvous and docking sensor for two cooperating spacecraft was studied. The polarized interferometer is a radio frequency system for long range, real time determination of relative position and attitude. Range is determined by round trip signal timing. Direction is determined by radio interferometry. Relative roll is determined from signal polarization. Each spacecraft is equipped with a transponder and an antenna array. The antenna arrays consist of four crossed dipoles that can transmit or receive either circularly or linearly polarized signals. The active spacecraft is equipped with a sophisticated transponder and makes all measurements. The transponder on the passive spacecraft is a relatively simple repeater. An initialization algorithm is developed to estimate position and attitude without any a priori information. A tracking algorithm based upon minimum variance linear estimators is also developed. Techniques to simplify the transponder on the passive spacecraft are investigated and a suitable configuration is determined. A multiple carrier CW signal format is selected. The dependence of range accuracy and ambiguity resolution error probability are derived and used to design a candidate system. The validity of the design and the feasibility of the polarized interferometer concept are verified by simulation.

  14. Polarized-interferometer feasibility study

    NASA Technical Reports Server (NTRS)

    Raab, F. H.

    1983-01-01

    The feasibility of using a polarized-interferometer system as a rendezvous and docking sensor for two cooperating spacecraft was studied. The polarized interferometer is a radio frequency system for long range, real time determination of relative position and attitude. Range is determined by round trip signal timing. Direction is determined by radio interferometry. Relative roll is determined from signal polarization. Each spacecraft is equipped with a transponder and an antenna array. The antenna arrays consist of four crossed dipoles that can transmit or receive either circularly or linearly polarized signals. The active spacecraft is equipped with a sophisticated transponder and makes all measurements. The transponder on the passive spacecraft is a relatively simple repeater. An initialization algorithm is developed to estimate position and attitude without any a priori information. A tracking algorithm based upon minimum variance linear estimators is also developed. Techniques to simplify the transponder on the passive spacecraft are investigated and a suitable configuration is determined. A multiple carrier CW signal format is selected. The dependence of range accuracy and ambiguity resolution error probability are derived and used to design a candidate system. The validity of the design and the feasibility of the polarized interferometer concept are verified by simulation.

  15. Lunar escape systems feasibility study

    NASA Technical Reports Server (NTRS)

    Matzenauer, J. O.

    1976-01-01

    Results are presented for a study conducted to determine the feasibility of simple lunar escape system concepts, to develop a spectrum of operational data, and to identify techniques and configurations suitable for the emergency escape mission. The study demonstrated the feasibility of the lunar emergency escape-to-orbit system (LESS) designed to provide a means for the two-man crew of a lunar module (LM) or extended-stay LM (ELM) to escape from the lunar surface in the event that the LM/ELM ascent stage becomes unsafe or is otherwise unable to take off. The LESS is to carry the two astronauts to a safe lunar orbit, where the Apollo command and service modules (CSM) are to be used for rendezvous and rescue, all within the lifetime of the backpack life support system (about 4 hr). It is concluded that simple manual control modes are sufficient, that simple boost profiles are acceptable, and that one man can deploy and set up the LESS. Initial guidance data can be calculated for the LESS by Mission Control and transmitted via the LM/ELM uplink.

  16. Lake Roosevelt Fisheries Monitoring Program; 1988-1989 Annual Report.

    SciTech Connect

    Peone, Tim L.; Scholz, Allan T.; Griffith, James R.

    1990-10-01

    In the Northwest Power Planning Council's 1987 Columbia River Basin Fish and Wildlife Program (NPPC 1987), the Council directed the Bonneville Power Administration (BPA) to construct two kokanee salmon (Oncorhynchus nerka) hatcheries as partial mitigation for the loss of anadromous salmon and steelhead incurred by construction of Grand Coulee Dam [Section 903 (g)(l)(C)]. The hatcheries will produce kokanee salmon for outplanting into Lake Roosevelt as well as rainbow trout (Oncorhynchus mykiss) for the Lake Roosevelt net-pen program. In section 903 (g)(l)(E), the Council also directed BPA to fund a monitoring program to evaluate the effectiveness of the kokanee hatcheries. The monitoring program included the following components: (1) a year-round, reservoir-wide, creel survey to determine angler use, catch rates and composition, and growth and condition of fish; (2) assessment of kokanee, rainbow, and walleye (Stizostedion vitreum) feeding habits and densities of their preferred prey, and; (3) a mark and recapture study designed to assess the effectiveness of different locations where hatchery-raised kokanee and net pen reared rainbow trout are released. The above measures were adopted by the Council based on a management plan, developed by the Upper Columbia United Tribes Fisheries Center, Spokane Indian Tribe, Colville Confederated Tribes, Washington Department of Wildlife, and National Park Service, that examined the feasibility of restoring and enhancing Lake Roosevelt fisheries (Scholz et al. 1986). In July 1988, BPA entered into a contract with the Spokane Indian Tribe to initiate the monitoring program. The projected duration of the monitoring program is through 1995. This report contains the results of the monitoring program from August 1988 to December 1989.

  17. Photoacoustic biopsy: a feasibility study

    NASA Astrophysics Data System (ADS)

    Xu, Guan; Tomlins, Scott A.; Siddiqui, Javed; Davis, Mandy A.; Kunju, Lakshmi P.; Wei, John T.; Wang, Xueding

    2015-03-01

    Photoacoustic (PA) measurements encode the information associated with both physical microstructures and chemical contents in biological tissues. A two-dimensional physio-chemical spectrogram (PCS) can be formulated by combining the power spectra of PA signals acquired at a series of optical wavelengths. The analysis of PCS, or namely PA physio-chemical analysis (PAPCA), enables the quantification of the concentrations and the spatial distributions of a variety of chemical components in the tissue. The chemical components and their distribution are the two major features observed in the biopsy procedures which have been regarded as the gold standard of the diagnosis of many diseases. Taking non-alcoholic fatty liver disease and prostate cancer for example, this study investigates the feasibility of PAPCA in characterizing the histopathological changes in the diseased conditions in biological tissue. A catheter based setup facilitating measurement in deep tissues was also proposed and tested.

  18. Intersatellite quantum communication feasibility study

    NASA Astrophysics Data System (ADS)

    Tomaello, Andrea; Dall'Arche, Alberto; Naletto, Giampiero; Villoresi, Paolo

    2011-08-01

    The shift in the Communication paradigm from the bit to the qubit is increasingly exploited in terrestrial long range links and networks, with strong potentials in secure communications, quantum computing and metrology. The space-to-ground quantum key distribution was also considered as feasible. A new different scenario for the quantum communications is that of the intersatellite link. In this study we focus on the extension of intersatellite communications into the quantum domain. The long distances involved and the fast relative motion are severe constraints, partially compensated by the absence of beam degradation due to the propagation in the atmosphere as well as the relatively low background noise level. We address the conception of the optical terminal and the predicted performances in the case of constellations of LEO and MEO satellite including the quantum communications and quantum teleportation.

  19. Preliminary guided rocket feasibility study

    NASA Technical Reports Server (NTRS)

    Nolan, M. B.; Celmer, J. J.

    1973-01-01

    The feasibility of actively guiding sounding rockets to reduce impact dispersion has been investigated. The theoretical probability of range safety thrust termination for several high performance rockets was combined with the cost of acquiring the extended range at White Sands Missile Range (WSMR) to establish a guidance system price ceiling of $20K per flight. Guiding the Black Brant VC (BBVC) for the first five seconds of flight results in sufficient dispersion reduction to impact within the standard range boundaries at WSMR. The guidance system thrust level required to statically control the vehicle to a nominal-wind weighted trajectory for five seconds is between 150-200 pounds. A six-degree-of-freedom trajectory program with guidance simulation capability has been developed and the equations are presented.

  20. Shuttle seated extraction feasibility study

    NASA Technical Reports Server (NTRS)

    Onagel, Steven R.; Bement, Laurence J.

    1989-01-01

    Following the Space Shuttle Challenger accident, serious attention has turned to in-flight escape. Prior to the resumption of flight, a manual bailout system was qualified and installed. For the long term, a seated extraction system to expand the escape envelope is being investigated. This paper describes a 1987 study, conducted jointly by NASA/Johnson Space Center and Langley Research Center, to determine the feasibility of modifying the Space Shuttle Orbiters to incorporate the seated extraction system. Results of the study are positive, indicating retrofit opportunity and high probability of escape for early ascent, late entry, and even for uncontrolled flight such as the Challenger breakup. The system, as envisioned, can extract seven crewmembers within two seconds.

  1. Shuttle seated extraction feasibility study

    NASA Astrophysics Data System (ADS)

    Onagel, Steven R.; Bement, Laurence J.

    Following the Space Shuttle Challenger accident, serious attention has turned to in-flight escape. Prior to the resumption of flight, a manual bailout system was qualified and installed. For the long term, a seated extraction system to expand the escape envelope is being investigated. This paper describes a 1987 study, conducted jointly by NASA/Johnson Space Center and Langley Research Center, to determine the feasibility of modifying the Space Shuttle Orbiters to incorporate the seated extraction system. Results of the study are positive, indicating retrofit opportunity and high probability of escape for early ascent, late entry, and even for uncontrolled flight such as the Challenger breakup. The system, as envisioned, can extract seven crewmembers within two seconds.

  2. IPNS upgrade: A feasibility study

    SciTech Connect

    1995-04-01

    Many of Argonne National Laboratory`s (ANL`s) scientific staff members were very active in R&D work related to accelerator-based spoliation sources in the 1970s and early 1980s. In 1984, the Seitz/Eastman Panel of the National Academy of Sciences reviewed U.S. materials science research facilities. One of the recommendations of this panel was that the United States build a reactor-based steady-state source, the Advanced Neutron Source (ANS), at Oak Ridge National Laboratory. Subsequently, R&D activities related to the design of an accelerator-based source assumed a lower priority. The resumption of pulsed-source studies in this country started simultaneously with design activities in Europe aimed at the European Spallation Source (ESS). The European Community funded a workshop in September 1991 to define the parameters of the ESS. Participants in this workshop included both accelerator builders and neutron source users. A consortium of European countries has proposed to build a 5-MW pulsed source, and a feasibility study is currently under way. Soon after the birth of the ESS, a small group at ANL set about bringing themselves up to date on pulsed-source information since 1984 and studied the feasibility of upgrading ANL`s Intense Pulsed Neutron Source (IPNS) to 1 MW by means of a rapidly cycling synchrotron that could be housed, along with its support facilities, in existing buildings. In early 1993, the Kohn panel recommended that (1) design and construction of the ANS should be completed according to the proposed project schedule and (2) development of competitive proposals for cost-effective design and construction of a 1-MW pulsed spallation source should be authorized immediately.

  3. World Ships - Architectures & Feasibility Revisited

    NASA Astrophysics Data System (ADS)

    Hein, A. M.; Pak, M.; Putz, D.; Buhler, C.; Reiss, P.

    A world ship is a concept for manned interstellar flight. It is a huge, self-contained and self-sustained interstellar vehicle. It travels at a fraction of a per cent of the speed of light and needs several centuries to reach its target star system. The well- known world ship concept by Alan Bond and Anthony Martin was intended to show its principal feasibility. However, several important issues haven't been addressed so far: the relationship between crew size and robustness of knowledge transfer, reliability, and alternative mission architectures. This paper addresses these gaps. Furthermore, it gives an update on target star system choice, and develops possible mission architectures. The derived conclusions are: a large population size leads to robust knowledge transfer and cultural adaptation. These processes can be improved by new technologies. World ship reliability depends on the availability of an automatic repair system, as in the case of the Daedalus probe. Star systems with habitable planets are probably farther away than systems with enough resources to construct space colonies. Therefore, missions to habitable planets have longer trip times and have a higher risk of mission failure. On the other hand, the risk of constructing colonies is higher than to establish an initial settlement on a habitable planet. Mission architectures with precursor probes have the potential to significantly reduce trip and colonization risk without being significantly more costly than architectures without. In summary world ships remain an interesting concept, although they require a space colony-based civilization within our own solar system before becoming feasible.

  4. Economic Feasibility of Recycling Photovoltaic Modules

    SciTech Connect

    Choi, J.K.; Fthenakis, V.

    2010-12-01

    The market for photovoltaic (PV) electricity generation has boomed over the last decade, and its expansion is expected to continue with the development of new technologies. Taking into consideration the usage of valuable resources and the generation of emissions in the life cycle of photovoltaic technologies dictates proactive planning for a sound PV recycling infrastructure to ensure its sustainability. PV is expected to be a 'green' technology, and properly planning for recycling will offer the opportunity to make it a 'double-green' technology - that is, enhancing life cycle environmental quality. In addition, economic feasibility and a sufficient level of value-added opportunity must be ensured, to stimulate a recycling industry. In this article, we survey mathematical models of the infrastructure of recycling processes of other products and identify the challenges for setting up an efficient one for PV. Then we present an operational model for an actual recycling process of a thin-film PV technology. We found that for the case examined with our model, some of the scenarios indicate profitable recycling, whereas in other scenarios it is unprofitable. Scenario SC4, which represents the most favorable scenario by considering the lower bounds of all costs and the upper bound of all revenues, produces a monthly profit of $107,000, whereas the least favorable scenario incurs a monthly loss of $151,000. Our intent is to extend the model as a foundation for developing a framework for building a generalized model for current-PV and future-PV technologies.

  5. Muon muon collider: Feasibility study

    SciTech Connect

    1996-06-18

    A feasibility study is presented of a 2 + 2 TeV muon collider with a luminosity of L = 10{sup 35} cm{sup {minus}2} s{sup {minus}1}. The resulting design is not optimized for performance, and certainly not for cost; however, it does suffice--the authors believe--to allow them to make a credible case, that a muon collider is a serious possibility for particle physics and, therefore, worthy of R and D support so that the reality of, and interest in, a muon collider can be better assayed. The goal of this support would be to completely assess the physics potential and to evaluate the cost and development of the necessary technology. The muon collider complex consists of components which first produce copious pions, then capture the pions and the resulting muons from their decay; this is followed by an ionization cooling channel to reduce the longitudinal and transverse emittance of the muon beam. The next stage is to accelerate the muons and, finally, inject them into a collider ring which has a small beta function at the colliding point. This is the first attempt at a point design and it will require further study and optimization. Experimental work will be needed to verify the validity of diverse crucial elements in the design.

  6. Is global measles eradication feasible?

    PubMed

    de Quadros, C A

    2006-01-01

    Measles is one of most infectious diseases. Before the introduction of the measles vaccine, practically all children in the long run contracted measles. By the end of the 1980s most countries of the world had incorporated measles vaccine into their routine vaccination programs. Globally, some 800,000 deaths due to measles still occur every year, half of them in Africa. Eradication of measles would play an important role in improving child survival. The goal to eradicate measles from the Americas was set by the Pan American Sanitary Conference in 1994. Progress to date has been remarkable. Measles is no longer an endemic disease in the Americas and interruption of transmission has been documented in most countries. As of August 2005, 3 years have elapsed since the detection of the last indigenous case in Venezuela in September 2002. This experience shows that interruption of measles transmission can be achieved and sustained over a long period of time and that global eradication is feasible if appropriate strategy is implemented. Even in a new paradigm in which eradication is not followed by the discontinuation of vaccination, eradication of measles will be a good investment to avoid expensive epidemics and save the almost one million children that die every year to infection with the measles virus. It is not a dream to think that we will se a world free of measles by the year 2015. PMID:16989269

  7. Can Communicative Principles Enhance Classical Language Acquisition?

    ERIC Educational Resources Information Center

    Overland, Paul; Fields, Lee; Noonan, Jennifer

    2011-01-01

    Is it feasible for nonfluent instructors to teach Biblical Hebrew by communicative principles? If it is feasible, will communicative instruction enhance postsecondary learning of a classical language? To begin answering these questions, two consultants representing second language acquisition (SLA) and technology-assisted language learning led 8…

  8. Is outpatient robotic pyeloplasty feasible?

    PubMed

    Finkelstein, Julia B; Van Batavia, Jason P; Casale, Pasquale

    2016-09-01

    With increased experience, many laparoscopic procedures have evolved from mandatory same-day admission to the outpatient setting. Given the shorter operative time and length of stay, the potential to perform robotic surgery as an outpatient procedure exists. We sought to describe our initial experience with performing robotic-assisted laparoscopic pyeloplasty (RP) on children in an outpatient setting. We retrospectively reviewed a prospectively collected database of all patients undergoing RP from July 2012 to May 2014 by a single surgeon. All patients discharged home within 12 h of completion of surgery were included in the analysis. Prior to discharge the Wong-Baker Pain Scale 1-10 was reviewed and given to all patients. All patients were prescribed oxybutynin and phenazopyridine for bladder spasms and stent discomfort. Post-operative follow-up telephone calls were made inquiring about oral intake, pain control, constitutional symptoms, and voiding issues. Readmission rates and post-operative outcomes were reviewed. During the study period, 62 children underwent RP and 13 patients (21 %) were selected for outpatient management. These 7 boys and 6 girls had a mean age of 8.1 years old. Of the 13 patients, 11 patients had left-sided procedures and 2 had right; all had primary UPJO. Mean pain score was 2.7 in the first 12 h at home. Within 24 h, the pain score decreased to a mean of 2.2. No patient required opioid analgesics and no child required admission after surgery. At 3-month follow-up, 7 patients had resolved hydronephrosis, 5 had improved hydronephrosis and 1 was unchanged. MAG3 renal scan in the latter patient showed no sign of obstruction. Outpatient RP is feasible and appears to be safe. Great care must be taken when selecting which patients can be fast tracked. PMID:27026272

  9. Beluga coal gasification feasibility study

    SciTech Connect

    Robert Chaney; Lawrence Van Bibber

    2006-07-15

    The objective of the study was to determine the economic feasibility of developing and siting a coal-based integrated gasification combined-cycle (IGCC) plant in the Cook Inlet region of Alaska for the co-production of electric power and marketable by-products. The by-products, which may include synthesis gas, Fischer-Tropsch (F-T) liquids, fertilizers such as ammonia and urea, alcohols, hydrogen, nitrogen and carbon dioxide, would be manufactured for local use or for sale in domestic and foreign markets. This report for Phase 1 summarizes the investigation of an IGCC system for a specific industrial setting on the Cook Inlet, the Agrium U.S. Inc. ('Agrium') fertilizer plant in Nikiski, Alaska. Faced with an increase in natural gas price and a decrease in supply, the Agrium is investigating alternatives to gas as feed stock for their plant. This study considered all aspects of the installation and infrastructure, including: coal supply and cost, coal transport costs, delivery routes, feedstock production for fertilizer manufacture, plant steam and power, carbon dioxide (CO{sub 2}) uses, markets for possible additional products, and environmental permit requirements. The Cook Inlet-specific Phase 1 results, reported here, provided insight and information that led to the conclusion that the second study should be for an F-T plant sited at the Usibelli Coal Mine near Healy, Alaska. This Phase 1 case study is for a very specific IGCC system tailored to fit the chemical and energy needs of the fertilizer manufacturing plant. It demonstrates the flexibility of IGCC for a variety of fuel feedstocks depending on plant location and fuel availability, as well as the available variety of gas separation, gas cleanup, and power and steam generation technologies to fit specific site needs. 18 figs., 37 tabs., 6 apps.

  10. Earthquake Alert System feasibility study

    SciTech Connect

    Harben, P.E.

    1991-12-01

    An Earthquake Alert System (EAS) could give several seconds to several tens of seconds warning before the strong motion from a large earthquake arrives. Such a system would include a large network of sensors distributed within an earthquake-prone region. The sensors closest to the epicenter of a particular earthquake would transmit data at the speed of light to a central processing center, which would broadcast an area-wide alarm in advance of the spreading elastic wave energy from the earthquake. This is possible because seismic energy travels slowly (3--6 km/s) compared to the speed of light. Utilities, public and private institutions, businesses, and the general public would benefit from an EAS. Although many earthquake protection systems exist that automatically shut down power, gas mains, etc. when ground motion at a facility reaches damaging levels, not EAS -- that is, a system that can provide warning in advance of elastic wave energy arriving at a facility -- has ever been developed in the United States. A recent study by the National Academy of Sciences (NRC, 1991) concludes that an EAS is technically feasible and strongly recommends installing a prototype system that makes use of existing microseismic stations as much as possible. The EAS concept discussed here consists of a distributed network of remote seismic stations that measure weak and strong earth motion and transmit the data in real time to central facility. This facility processes the data and issues warning broadcasts in the form of information packets containing estimates of earthquake location, zero time (the time the earthquake began), magnitude, and reliability of the predictions. User of the warning broadcasts have a dedicated receiver that monitors the warning broadcast frequency. The user also has preprogrammed responses that are automatically executed when the warning information packets contain location and magnitude estimates above a facility`s tolerance.

  11. Earthquake Alert System feasibility study

    SciTech Connect

    Harben, P.E.

    1991-12-01

    An Earthquake Alert System (EAS) could give several seconds to several tens of seconds warning before the strong motion from a large earthquake arrives. Such a system would include a large network of sensors distributed within an earthquake-prone region. The sensors closest to the epicenter of a particular earthquake would transmit data at the speed of light to a central processing center, which would broadcast an area-wide alarm in advance of the spreading elastic wave energy from the earthquake. This is possible because seismic energy travels slowly (3--6 km/s) compared to the speed of light. Utilities, public and private institutions, businesses, and the general public would benefit from an EAS. Although many earthquake protection systems exist that automatically shut down power, gas mains, etc. when ground motion at a facility reaches damaging levels, not EAS -- that is, a system that can provide warning in advance of elastic wave energy arriving at a facility -- has ever been developed in the United States. A recent study by the National Academy of Sciences (NRC, 1991) concludes that an EAS is technically feasible and strongly recommends installing a prototype system that makes use of existing microseismic stations as much as possible. The EAS concept discussed here consists of a distributed network of remote seismic stations that measure weak and strong earth motion and transmit the data in real time to central facility. This facility processes the data and issues warning broadcasts in the form of information packets containing estimates of earthquake location, zero time (the time the earthquake began), magnitude, and reliability of the predictions. User of the warning broadcasts have a dedicated receiver that monitors the warning broadcast frequency. The user also has preprogrammed responses that are automatically executed when the warning information packets contain location and magnitude estimates above a facility's tolerance.

  12. Asteroid Return Mission Feasibility Study

    NASA Technical Reports Server (NTRS)

    Brophy, John R.; Gershman, Robert; Landau, Damon; Polk, James; Porter, Chris; Yeomans, Don; Allen, Carlton; Williams, Willie; Asphaug, Erik

    2011-01-01

    This paper describes an investigation into the technological feasibility of finding, characterizing, robotically capturing, and returning an entire Near-Earth Asteroid (NEA) to the International Space Station (ISS) for scientific investigation, evaluation of its resource potential, determination of its internal structure and other aspects important for planetary defense activities, and to serve as a testbed for human operations in the vicinity of an asteroid. Reasonable projections suggest that several dozen candidates NEAs in the size range of interest (approximately 2-m diameter) will be known before the end of the decade from which a suitable target could be selected. The conceptual mission objective is to return an approximately 10,000-kg asteroid to the ISS in a total flight time of approximately 5 years using a single Evolved Expendable Launch Vehicle. Preliminary calculations indicate that this could be accomplished using a solar electric propulsion (SEP) system with high-power Hall thrusters and a maximum power into the propulsion system of approximately 40 kW. The SEP system would be used to provide all of the post-launch delta V. The asteroid would have an unrestricted Earth return Planetary Protection categorization, and would be curated at the ISS where numerous scientific and resource utilization experiments would be conducted. Asteroid material brought to the ground would be curated at the NASA Johnson Space Center. This preliminary study identified several areas where additional work is required, but no show stoppers were identified for the approach that would return an entire 10,000-kg asteroid to the ISS in a mission that could be launched by the end of this decade.

  13. 7 CFR 1980.442 - Feasibility studies.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 14 2010-01-01 2009-01-01 true Feasibility studies. 1980.442 Section 1980.442... studies. A feasibility study by a recognized independent consultant will be required for all loans, except as provided in this paragraph. The cost of the study will be borne by the borrower and may be...

  14. 25 CFR 41.7 - Feasibility studies.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... initiate a feasibility study to determine whether there is justification to encourage and maintain a Community College for such tribe or tribes. The feasibility study shall give consideration to the following..., linguistics, or cultural differences; (4) Isolation; (5) Presence of alternate education sources; (6)...

  15. 25 CFR 41.7 - Feasibility studies.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... initiate a feasibility study to determine whether there is justification to encourage and maintain a Community College for such tribe or tribes. The feasibility study shall give consideration to the following..., linguistics, or cultural differences; (4) Isolation; (5) Presence of alternate education sources; (6)...

  16. 25 CFR 41.7 - Feasibility studies.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... initiate a feasibility study to determine whether there is justification to encourage and maintain a Community College for such tribe or tribes. The feasibility study shall give consideration to the following..., linguistics, or cultural differences; (4) Isolation; (5) Presence of alternate education sources; (6)...

  17. 25 CFR 41.7 - Feasibility studies.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... initiate a feasibility study to determine whether there is justification to encourage and maintain a Community College for such tribe or tribes. The feasibility study shall give consideration to the following..., linguistics, or cultural differences; (4) Isolation; (5) Presence of alternate education sources; (6)...

  18. 25 CFR 41.7 - Feasibility studies.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Feasibility studies. 41.7 Section 41.7 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION GRANTS TO TRIBALLY CONTROLLED COMMUNITY COLLEGES AND NAVAJO COMMUNITY COLLEGE Tribally Controlled Community Colleges § 41.7 Feasibility studies. (a) Grants under § 41.8 of this subpart may be...

  19. Sault Tribe Wind Energy Feasibility Study

    SciTech Connect

    Toni Osterhout; Global Energy Concepts

    2005-07-31

    The Sault Tribe conducted a feasibility study on tribal lands in the Upper Peninsula of Michigan to determine the technical and economic feasibility of both small and large-scale wind power development on tribal lands. The study included a wind resource assessment, transmission system analysis, engineering and regulatory analyzes and assessments.

  20. 7 CFR 762.125 - Financial feasibility.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 7 2014-01-01 2014-01-01 false Financial feasibility. 762.125 Section 762.125 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS GUARANTEED FARM LOANS § 762.125 Financial feasibility. (a) General. Except...

  1. 25 CFR 700.465 - Technical feasibility.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Technical feasibility. 700.465 Section 700.465 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Discretionary Funds § 700.465 Technical feasibility. Unless required by a non-Commission source of financial assistance, completed plans and...

  2. 12 CFR 618.8020 - Feasibility requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... costs and risks involved in offering the program, such as management and personnel requirements... association provides, it must document program feasibility. The feasibility analysis shall include the following: (a) Support for the determination that the related service is authorized; and (b) An overall...

  3. 7 CFR 1980.442 - Feasibility studies.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... which might affect the success of the enterprise. The report shall also identify and estimate project... include but not be limited to: (a) Economic feasibility. Information related to the project site... economic impact of the project. (b) Market feasibility. Information on the sales organization...

  4. 7 CFR 1980.442 - Feasibility studies.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... which might affect the success of the enterprise. The report shall also identify and estimate project... include but not be limited to: (a) Economic feasibility. Information related to the project site... economic impact of the project. (b) Market feasibility. Information on the sales organization...

  5. 7 CFR 762.125 - Financial feasibility.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Financial feasibility. 762.125 Section 762.125 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS GUARANTEED FARM LOANS § 762.125 Financial feasibility. (a) General....

  6. 7 CFR 762.125 - Financial feasibility.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 7 2011-01-01 2011-01-01 false Financial feasibility. 762.125 Section 762.125 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS GUARANTEED FARM LOANS § 762.125 Financial feasibility. (a) General. Except...

  7. Multnomah County Hydrokinetic Feasibility Study: Final Feasibility Study Report

    SciTech Connect

    Spain, Stephen

    2012-03-15

    HDR has completed a study of the technical, regulatory, and economic feasibility of installing hydrokinetic turbines under the Morrison, Broadway, and Sellwood bridges. The primary objective of installing hydrokinetic turbines is a demonstration of in-stream hydrokinetic technologies for public education and outreach. Due to the low gradient of the Lower Willamette and the effects of the tide, velocities in the area in consideration are simply not high enough to economically support a commercial installation. While the velocities in the river may at times provide enough energy for a commercial turbine to reach capacity, the frequency and duration of high flow events which provide suitable velocities is not sufficient to support a commercial hydrokinetic installation. We have observed that over an 11 year period, daily average velocities in the Lower Willamette exceeded a nominal cut-in speed of 0.75 m/s only 20% of the time, leaving net zero power production for the remaining 80% of days. The Sellwood Bridge site was estimated to have the best hydrokinetic resource, with an estimated average annual production of about 9,000 kWh. The estimated production could range from 2,500 kWh to 15,000 kWh. Based on these energy estimates, the amount of revenue generated through either a power purchase agreement (PPA) or recovered through net metering is not sufficient to repay the project costs within the life of the turbine. The hydrokinetic resource at the Morrison and Broadway Bridges is slightly smaller than at the Sellwood Bridge. While the Broadway and Morrison Bridges have existing infrastructure that could be utilized, the project is not expected to generate enough revenue to repay the investment. Despite low velocities and energy production, the sites themselves are favorable for installation of a demonstration or experimental project. With high public interest in renewable energy, the possibility exists to develop a hydrokinetic test site which could provide

  8. WERF MACT Feasibility Study Report

    SciTech Connect

    B. Bonnema; D. Moser; J. Riedesel; K. Kooda; K. Liekhus; K. Rebish; S. Poling

    1998-11-01

    This study was undertaken to determine the technical feasibility of upgrading the Waste Experimental Reduction Facility (WERF) at the Idaho National Engineering and Environmental Laboratory to meet the offgas emission limits proposed in the Maximum Achievable Control Technologies (MACT)rule. Four practicable offgas treatment processes were identified, which, if installed, would enable the WERF to meet the anticipated MACT emission limits for dioxins and furans (D/F), hydrochloric acid (HCI), and mercury (Hg). Due to the three-year time restraint for MACT compliance, any technology chosen for the upgrade must be performed within the general plant project funding limit of $5 M. The option selected consists of a partial-quench evaporative cooler with dry sorbent injection for HCI removal followed by a sulfur-impregnated activated carbon bed for Hg control. The planning cost estimate for implementing the option is $4.17 M (with 24% contingency). The total estimated cost includes capital costs, design and construction costs, and project management costs. Capital costs include the purchase of a new offgas evaporative cooler, a dry sorbent injection system with reagent storage, a new fabric filter baghouse, a fixed carbon bed absorber, and two offgas induced draft exhaust fans. It is estimated that 21 months will be required to complete the recommended modification to the WERF. The partial-quench cooler is designed to rapidly cool the offgas exiting the secondary combustion chamber to minimize D/F formation. Dry sorbent injection of an alkali reagent into the offgas is recommended. The alkali reacts with the HCI to form a salt, which is captured with the fly ash in the baghouse. A design HCI removal efficiency of 97.2% allows for the feeding 20 lbs/hr of chlorine to the WERF incinerator. The sorbent feed rate can be adjusted to achieve the desired HCI removal efficiency. A fixed bed of sulfur-impregnated carbon was conservatively sized for a total Hg removal capacity when

  9. Sherman Creek Hatchery; 1995-1996 Annual Report.

    SciTech Connect

    Combs, Mitch

    1997-01-01

    The Sherman Creek Hatchery (SCH) was designed to rear 1.7 million kokanee fry for acclimation and imprinting during the spring and early summer. Additionally, it was designed to trap all available returning adult kokanee during the fall for broodstock operations and evaluations. Since the start of this program, the operations of the SCH have been modified to better achieve program goals. These strategic changes have been the result of recommendations through the Lake Roosevelt Hatcheries Coordination Team (LRHCT) and were implemented to enhance imprinting, improve survival and operate the two kokanee facilities more effectively. The primary change has been to replace the kokanee fingerling program with a kokanee yearling (post smolt) program. The second significant change has been to rear 120,000 rainbow trout fingerling at SCH from July through October to enable the Spokane Tribal Hatchery (STH) to rear additional kokanee for the yearling program.

  10. Passive vapor extraction feasibility study

    SciTech Connect

    Rohay, V.J.

    1994-06-30

    Demonstration of a passive vapor extraction remediation system is planned for sites in the 200 West Area used in the past for the disposal of waste liquids containing carbon tetrachloride. The passive vapor extraction units will consist of a 4-in.-diameter pipe, a check valve, a canister filled with granular activated carbon, and a wind turbine. The check valve will prevent inflow of air that otherwise would dilute the soil gas and make its subsequent extraction less efficient. The granular activated carbon is used to adsorb the carbon tetrachloride from the air. The wind turbine enhances extraction rates on windy days. Passive vapor extraction units will be designed and operated to meet all applicable or relevant and appropriate requirements. Based on a cost analysis, passive vapor extraction was found to be a cost-effective method for remediation of soils containing lower concentrations of volatile contaminants. Passive vapor extraction used on wells that average 10-stdft{sup 3}/min air flow rates was found to be more cost effective than active vapor extraction for concentrations below 500 parts per million by volume (ppm) of carbon tetrachloride. For wells that average 5-stdft{sup 3}/min air flow rates, passive vapor extraction is more cost effective below 100 ppm.

  11. Conceptual Thermal Treatment Technologies Feasibility Study

    SciTech Connect

    Suer, A.

    1996-02-28

    This report presents a conceptual Thermal Treatment Technologies Feasibility Study (FS) for the Savannah River Site (SRS) focusing exclusively on thermal treatment technologies for contaminated soil, sediment, or sludge remediation projects.

  12. Three Affliated Tribes Renewable Energy Feasibility Study

    SciTech Connect

    Belvin Pete; Kent Good; Krista Gordon; Ed McCarthy,

    2006-05-26

    The Three Affliated Tribes on the Fort Berthold Reservation studied the feasibility of a commercial wind facility on land selected and owned by the Tribes and examined the potential for the development of renewable energy resources on Tribal Lands.

  13. Renewable Energy Park - Preliminary Feasibility & Engineering Report

    SciTech Connect

    Ariwite, Roderick

    2015-07-31

    This "Renewable Energy Park - Preliminary Feasibility & Engineering Report" seeks to provide an overall assessment and review of renewable energy development opportunities on the Fallon Indian Reservation and Colony Lands.

  14. Single Institution Feasibility Trials - Cancer Imaging Program

    Cancer.gov

    Within the CIP program, the current R21 mechanism provides potential funding for small, single institution feasibility trials. The current announcement is titled In Vivo Cancer Imaging Exploratory/Developmental Grants.

  15. Muon Muon Collider: Feasibility Study

    SciTech Connect

    Gallardo, J.C.; Palmer, R.B.; Tollestrup, A.V.; Sessler, A.M.; Skrinsky, A.N.; Ankenbrandt, C.; Geer, S.; Griffin, J.; Johnstone, C.; Lebrun, P.; McInturff, A.; Mills, Frederick E.; Mokhov, N.; Moretti, A.; Neuffer, D.; Ng, K.Y.; Noble, R.; Novitski, I.; Popovic, M.; Qian, C.; Van Ginneken, A. /Fermilab /Brookhaven /Wisconsin U., Madison /Tel Aviv U. /Indiana U. /UCLA /LBL, Berkeley /SLAC /Argonne /Sobolev IM, Novosibirsk /UC, Davis /Munich, Tech. U. /Virginia U. /KEK, Tsukuba /DESY /Novosibirsk, IYF /Jefferson Lab /Mississippi U. /SUNY, Stony Brook /MIT /Columbia U. /Fairfield U. /UC, Berkeley

    2012-04-05

    A feasibility study is presented of a 2 + 2 TeV muon collider with a luminosity of L = 10{sup 35} cm{sup -2}s{sup -1}. The resulting design is not optimized for performance, and certainly not for cost; however, it does suffice - we believe - to allow us to make a credible case, that a muon collider is a serious possibility for particle physics and, therefore, worthy of R and D support so that the reality of, and interest in, a muon collider can be better assayed. The goal of this support would be to completely assess the physics potential and to evaluate the cost and development of the necessary technology. The muon collider complex consists of components which first produce copious pions, then capture the pions and the resulting muons from their decay; this is followed by an ionization cooling channel to reduce the longitudinal and transverse emittance of the muon beam. The next stage is to accelerate the muons and, finally, inject them into a collider ring wich has a small beta function at the colliding point. This is the first attempt at a point design and it will require further study and optimization. Experimental work will be needed to verify the validity of diverse crucial elements in the design. Muons because of their large mass compared to an electron, do not produce significant synchrotron radiation. As a result there is negligible beamstrahlung and high energy collisions are not limited by this phenomena. In addition, muons can be accelerated in circular devices which will be considerably smaller than two full-energy linacs as required in an e{sup +} - e{sup -} collider. A hadron collider would require a CM energy 5 to 10 times higher than 4 TeV to have an equivalent energy reach. Since the accelerator size is limited by the strength of bending magnets, the hadron collider for the same physics reach would have to be much larger than the muon collider. In addition, muon collisions should be cleaner than hadron collisions. There are many detailed particle

  16. Comet nucleus impact probe feasibility study

    NASA Technical Reports Server (NTRS)

    Castro, A. J.

    1980-01-01

    A top level listing of the comet nucleus impact probe (CNIP) feasibility experiments requirements are presented. A conceptual configuration which shows that the feasibility of engineering the experiment is possible and describes the candidate hardware is discussed. The design studies required in order to design the operating experiment are outlined. An overview of a program plan used to estimate a rough order of magnitude cost for the CNIP experiment is given.

  17. White Earth Biomass/Biogas Feasibility Study

    SciTech Connect

    Triplett, Michael

    2015-03-12

    The White Earth Nation examined the feasibility of cost savings and fossil energy reduction through the installation of biogas/biomass boiler at the tribal casino. The study rejected biogas options due to availability and site constraints, but found a favorable environment for technical and financial feasibility of installing a 5 MMBtu hot water boiler system to offset 60-70 percent of current fuel oil and propane usage.

  18. Regulation of Romantic Love Feelings: Preconceptions, Strategies, and Feasibility.

    PubMed

    Langeslag, Sandra J E; van Strien, Jan W

    2016-01-01

    Love feelings can be more intense than desired (e.g., after a break-up) or less intense than desired (e.g., in long-term relationships). If only we could control our love feelings! We present the concept of explicit love regulation, which we define as the use of behavioral and cognitive strategies to change the intensity of current feelings of romantic love. We present the first two studies on preconceptions about, strategies for, and the feasibility of love regulation. Questionnaire responses showed that people perceive love feelings as somewhat uncontrollable. Still, in four open questions people reported to use strategies such as cognitive reappraisal, distraction, avoidance, and undertaking (new) activities to cope with break-ups, to maintain long-term relationships, and to regulate love feelings. Instructed up-regulation of love using reappraisal increased subjective feelings of attachment, while love down-regulation decreased subjective feelings of infatuation and attachment. We used the late positive potential (LPP) amplitude as an objective index of regulation success. Instructed love up-regulation enhanced the LPP between 300-400 ms in participants who were involved in a relationship and in participants who had recently experienced a romantic break-up, while love down-regulation reduced the LPP between 700-3000 ms in participants who were involved in a relationship. These findings corroborate the self-reported feasibility of love regulation, although they are complicated by the finding that love up-regulation also reduced the LPP between 700-3000 ms in participants who were involved in a relationship. To conclude, although people have the preconception that love feelings are uncontrollable, we show for the first time that intentional regulation of love feelings using reappraisal, and perhaps other strategies, is feasible. Love regulation will benefit individuals and society because it could enhance positive effects and reduce negative effects of romantic

  19. Regulation of Romantic Love Feelings: Preconceptions, Strategies, and Feasibility

    PubMed Central

    Langeslag, Sandra J. E.; van Strien, Jan W.

    2016-01-01

    Love feelings can be more intense than desired (e.g., after a break-up) or less intense than desired (e.g., in long-term relationships). If only we could control our love feelings! We present the concept of explicit love regulation, which we define as the use of behavioral and cognitive strategies to change the intensity of current feelings of romantic love. We present the first two studies on preconceptions about, strategies for, and the feasibility of love regulation. Questionnaire responses showed that people perceive love feelings as somewhat uncontrollable. Still, in four open questions people reported to use strategies such as cognitive reappraisal, distraction, avoidance, and undertaking (new) activities to cope with break-ups, to maintain long-term relationships, and to regulate love feelings. Instructed up-regulation of love using reappraisal increased subjective feelings of attachment, while love down-regulation decreased subjective feelings of infatuation and attachment. We used the late positive potential (LPP) amplitude as an objective index of regulation success. Instructed love up-regulation enhanced the LPP between 300–400 ms in participants who were involved in a relationship and in participants who had recently experienced a romantic break-up, while love down-regulation reduced the LPP between 700–3000 ms in participants who were involved in a relationship. These findings corroborate the self-reported feasibility of love regulation, although they are complicated by the finding that love up-regulation also reduced the LPP between 700–3000 ms in participants who were involved in a relationship. To conclude, although people have the preconception that love feelings are uncontrollable, we show for the first time that intentional regulation of love feelings using reappraisal, and perhaps other strategies, is feasible. Love regulation will benefit individuals and society because it could enhance positive effects and reduce negative effects of

  20. Fusion Guidance in Endovascular Peripheral Artery Interventions: A Feasibility Study

    SciTech Connect

    Sailer, Anna M. Haan, Michiel W. de Graaf, Rick de Zwam, Willem H. van; Schurink, Geert Willem H.; Nelemans, Patricia J.; Wildberger, Joachim E. Das, Marco

    2015-04-15

    PurposeThis study was designed to evaluate the feasibility of endovascular guidance by means of live fluoroscopy fusion with magnetic resonance angiography (MRA) and computed tomography angiography (CTA).MethodsFusion guidance was evaluated in 20 endovascular peripheral artery interventions in 17 patients. Fifteen patients had received preinterventional diagnostic MRA and two patients had undergone CTA. Time for fluoroscopy with MRA/CTA coregistration was recorded. Feasibility of fusion guidance was evaluated according to the following criteria: for every procedure the executing interventional radiologists recorded whether 3D road-mapping provided added value (yes vs. no) and whether PTA and/or stenting could be performed relying on the fusion road-map without need for diagnostic contrast-enhanced angiogram series (CEAS) (yes vs. no). Precision of the fusion road-map was evaluated by recording maximum differences between the position of the vasculature on the virtual CTA/MRA images and conventional angiography.ResultsAverage time needed for image coregistration was 5 ± 2 min. Three-dimensional road-map added value was experienced in 15 procedures in 12 patients. In half of the patients (8/17), intervention was performed relying on the fusion road-map only, without diagnostic CEAS. In two patients, MRA roadmap showed a false-positive lesion. Excluding three patients with inordinate movements, mean difference in position of vasculature on angiography and MRA/CTA road-map was 1.86 ± 0.95 mm, implying that approximately 95 % of differences were between 0 and 3.72 mm (2 ± 1.96 standard deviation).ConclusionsFluoroscopy with MRA/CTA fusion guidance for peripheral artery interventions is feasible. By reducing the number of CEAS, this technology may contribute to enhance procedural safety.

  1. A pilot feasibility study of a peer-led mindfulness program for medical students

    PubMed Central

    Danilewitz, Marlon; Bradwejn, Jacques; Koszycki, Diana

    2016-01-01

    Background Mindfulness meditation has gained momentum in medical circles for bolstering wellbeing and other facets of professionalism. This study evaluated the feasibility and benefits of a peer-led mindfulness meditation program (MMP) on medical student wellness and professionalism. Method Pre-clerkship students were recruited and randomized to the 8-week MMP or wait-list. Feasibility outcomes included ease of recruitment, program attendance and homework compliance. Other outcomes included self-reported psychological distress, empathy, self-compassion, mindfulness, altruism and program satisfaction. Results The MMP decreased levels of stress and enhanced mindfulness, self-compassion and altruism from baseline to post-study. Changes were not significant for the wait-list condition. Although satisfaction with the MMP was high compliance was suboptimal. Conclusions A peer-led MMP is feasible and may be a promising approach to enhance medical student wellbeing. Further research is needed to explore strategies to improve program compliance in this student population. PMID:27103950

  2. The Feasibility of a Common Course in Early Childhood Teacher Preparation Programs. Research Brief

    ERIC Educational Resources Information Center

    Scott-Little, Catherine; La Paro, Karen M.; Thomason, Amy C.; Pianta, Robert C.; Hamre, Bridget; Downer, Jason; Burchinal, Margaret; Howes, Carollee

    2011-01-01

    This study offers a glimpse into the feasibility and potential benefits of offering a common course across multiple institutions of higher education. The research-based course was designed to enhance students' knowledge and beliefs regarding intentional teaching practices in language and literacy instruction. Researchers found evidence that a…

  3. Developing Metacognitive and Discursive Activities in the Indonesian Mathematics Education. Results of a Feasibility Study

    ERIC Educational Resources Information Center

    Kaune, Christa; Cohors-Fresenborg, Elmar; Nowinska, Edyta; Marpaung, Yansen; Handayani, Novi

    2012-01-01

    This article reports on the findings of a German-Indonesian feasibility study, which has been conducted to examine whether a more extensive pilot study could be successful. The objective of the pilot study is to enhance the mathematical skills of Indonesian students in the 7th class by increasing the number of students who can really understand…

  4. Feasibility of a Recasting and Auditory Bombardment Treatment with Young Cochlear Implant Users

    ERIC Educational Resources Information Center

    Encinas, Danielle; Plante, Elena

    2016-01-01

    Purpose: There is little to guide clinicians in terms of evidence-based interventions for children with cochlear implants who demonstrate morpheme errors. This feasibility study tested the utility of a treatment targeting grammatical morpheme errors. Method: Three children (ages 4-5 years) received Enhanced Conversational Recast treatment, a…

  5. 77 FR 36419 - Feasibility of Enumerating “Specially Designed” Components

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-19

    ...As part of the President's Export Control Reform (ECR) Initiative, this ANPRM requests comments on the feasibility of positively identifying ``specially designed'' ``components'' on the Commerce Control List (CCL) so as to decrease the use of the term, which appears extensively throughout the CCL, and thereby facilitate enhanced public compliance with the Export Administration Regulations.......

  6. Feasibility of treating partially soluble wastewater in anaerobic sequencing batch biofilm reactor (ASBBR) with mechanical stirring.

    PubMed

    Pinho, Samantha Cristina; Ratusznei, Suzana Maria; Rodrigues, José Alberto Domingues; Foresti, Eugenio; Zaiat, Marcelo

    2005-03-01

    This work reports on the treatment of partially soluble wastewater in an anaerobic sequencing batch biofilm reactor, containing biomass immobilized on polyurethane matrices and stirred mechanically. The results showed that agitation provided optimal mixing and improved the overall organic matter consumption rates. The system showed to be feasible to enhance the treatment of partially soluble wastewaters. PMID:15491835

  7. Lake Roosevelt Fisheries Monitoring Program; 1990 Annual Report.

    SciTech Connect

    Griffith, Janelle R.; Scholz, Allan T.

    1991-09-01

    feasibility of restoring and enhancing Lake Roosevelt fisheries (Scholz et al. 1986). In July 1988, BPA entered into a contract with the Spokane Indian Tribe to initiate the monitoring program and continue research through 1995. This report contains the results of the monitoring program from January to December 1990.

  8. Northern New Mexico regional airport market feasibility

    SciTech Connect

    Drake, R.H.; Williams, D.S.

    1998-06-01

    This report is about the market for airline travel in northern New Mexico. Interest in developing a northern New Mexico regional airport has periodically surfaced for a number of years. The New Mexico State Legislature passed a memorial during the 1998 Second Session calling for the conduct of a study to determine the feasibility of building a new regional airport in NNM. This report is a study of the passenger market feasibility of such an airport. In addition to commercial passenger market feasibility, there are other feasibility issues dealing with siting, environmental impact, noise, economic impact, intermodal transportation integration, region-wide transportation services, airport engineering requirements, and others. These other feasibility issues are not analyzed in any depth in this report although none were discovered to be show-stoppers as a by-product of the authors doing research on the passenger market itself. Preceding the need for a detailed study of these other issues is the determination of the basic market need for an airport with regular commercial airline service in the first place. This report is restricted to an in-depth look at the market for commercial passenger air service in NNM. 20 figs., 8 tabs.

  9. The Feasibility and Acceptability of LISTEN for Loneliness

    PubMed Central

    Theeke, Laurie A.; Mallow, Jennifer A.; Barnes, Emily R.; Theeke, Elliott

    2015-01-01

    Purpose The purpose of this paper is to present the initial feasibility and acceptability of LISTEN (Loneliness Intervention using Story Theory to Enhance Nursing-sensitive outcomes), a new intervention for loneliness. Loneliness is a significant stressor and known contributor to multiple chronic health conditions in varied populations. In addition, loneliness is reported as predictive of functional decline and mortality in large samples of older adults from multiple cultures. Currently, there are no standard therapies recommended as effective treatments for loneliness. The paucity of interventions has limited the ability of healthcare providers to translate what we know about the problem of loneliness to active planning of clinical care that results in diminished loneliness. LISTEN was developed using the process for complex intervention development suggested by the Medical Research Council (MRC) [1] [2]. Methods Feasibility and acceptability of LISTEN were evaluated as the first objective of a longitudinal randomized trial which was set in a university based family medicine center in a rural southeastern community in Appalachia. Twenty-seven older adults [(24 women and 3 men, mean age: 75 (SD 7.50)] who were lonely, community-dwelling, and experiencing chronic illness, participated. Feasibility was evaluated by tracking recruitment efforts, enrollment, attendance to intervention sessions, attrition, and with feedback evaluations from study personnel. Acceptability was assessed using quantitative and qualitative evaluation data from participants. Results LISTEN was evaluated as feasible to deliver with no attrition and near perfect attendance. Participants ranked LISTEN as highly acceptable for diminishing loneliness with participants requesting a continuation of the program or development of additional sessions. Conclusions LISTEN is feasible to deliver in a primary healthcare setting and has the potential to diminish loneliness which could result in improvement

  10. Formed platelet combustor liner construction feasibility, phase A

    NASA Technical Reports Server (NTRS)

    Hayes, W. A.; Janke, D. E.

    1992-01-01

    Environments generated in high pressure liquid rocket engines impose severe requirements on regeneratively cooled combustor liners. Liners fabricated for use in high chamber pressures using conventional processes suffer from limitations that can impair operational cycle life and can adversely affect wall compatibility. Chamber liners fabricated using formed platelet technology provide an alternative to conventional regeneratively cooled liners (an alternative that has many attractive benefits). A formed platelet liner is made from a stacked assembly of platelets with channel features. The assembly is diffusion bonded into a flat panel and then three-dimensionally formed into a section of a chamber. Platelet technology permits the liner to have very precisely controlled and thin hot gas walls and therefore increased heat transfer efficiency. Further cooling efficiencies can be obtained through enhanced design flexibility. These advantages translate into increased cycle life and enhanced wall compatibility. The increased heat transfer efficiency can alternately be used to increase engine performance or turbopump life as a result of pressure drop reductions within the regeneratively cooled liner. Other benefits can be obtained by varying the materials of construction within the platelet liner to enhance material compatibility with operating environment or with adjoining components. Manufacturing cost savings are an additional benefit of a formed platelet liner. This is because of reduced touch labor and reduced schedule when compared to conventional methods of manufacture. The formed platelet technology is not only compatible with current state-of-the art combustion chamber structural support and manifolding schemes, it is also an enabling technology that allows the use of other high performance and potentially low cost methods of construction for the entire combustion chamber assembly. The contract under which this report is submitted contains three phases: (1) phase