Science.gov

Sample records for laboratory quality control

  1. Laboratory QualityLaboratory Quality ControlControl

    E-print Network

    Laboratory QualityLaboratory Quality ControlControl Nabil A. NIMER Dept . Biotechnology & Genetic Engineering Faculty of Science Philadelphia University #12;Definitions (1)Definitions (1) Quality Control

  2. Quality assurance/quality control manual; National Water Quality Laboratory

    USGS Publications Warehouse

    Pritt, J.W.; Raese, J.W.

    1995-01-01

    Quality-control practices are established for the operation of the U.S. Geological Survey's National Water Quality Laboratory. These practices specify how samples are preserved, shipped, and analyzed in the Laboratory. This manual documents the practices that are currently (1995) used in the Laboratory.

  3. 7 CFR 58.442 - Laboratory and quality control tests.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 3 2012-01-01 2012-01-01 false Laboratory and quality control tests. 58.442 Section... Service 1 Operations and Operating Procedures § 58.442 Laboratory and quality control tests. (a) Chemical... Methods or by other methods giving equivalent results. (b) Weight or volume control....

  4. 7 CFR 58.442 - Laboratory and quality control tests.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 3 2013-01-01 2013-01-01 false Laboratory and quality control tests. 58.442 Section... Service 1 Operations and Operating Procedures § 58.442 Laboratory and quality control tests. (a) Chemical... Methods or by other methods giving equivalent results. (b) Weight or volume control....

  5. 7 CFR 58.442 - Laboratory and quality control tests.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 3 2014-01-01 2014-01-01 false Laboratory and quality control tests. 58.442 Section... Service 1 Operations and Operating Procedures § 58.442 Laboratory and quality control tests. (a) Chemical... Methods or by other methods giving equivalent results. (b) Weight or volume control....

  6. 7 CFR 58.442 - Laboratory and quality control tests.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Laboratory and quality control tests. 58.442 Section 58.442 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL...

  7. 7 CFR 58.442 - Laboratory and quality control tests.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 3 2011-01-01 2011-01-01 false Laboratory and quality control tests. 58.442 Section 58.442 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL...

  8. QUALITY ASSURANCE / QUALITY CONTROL POLICY SOIL TESTING AND RESEARCH ANALYTICAL LABORATORY

    E-print Network

    Minnesota, University of

    QUALITY ASSURANCE / QUALITY CONTROL POLICY SOIL TESTING AND RESEARCH ANALYTICAL LABORATORY and Determination of Reporting Limits 21 10.0 Corrective Action 24 11.0 Quality Assurance Reports to Management 25 assurance, and it is our goal to provide high quality project support and technical resources to meet

  9. Quality control for diagnostic oral microbiology laboratories in European countries

    PubMed Central

    Rautemaa-Richardson, Riina; der Reijden Wa, Wil A Van; Dahlen, Gunnar; Smith, Andrew J.

    2011-01-01

    Participation in diagnostic microbiology internal and external quality control (QC) processes is good laboratory practice and an essential component of a quality management system. However, no QC scheme for diagnostic oral microbiology existed until 2009 when the Clinical Oral Microbiology (COMB) Network was created. At the European Oral Microbiology Workshop in 2008, 12 laboratories processing clinical oral microbiological samples were identified. All these were recruited to participate into the study and six laboratories from six European countries completed both the online survey and the first QC round. Three additional laboratories participated in the second round. Based on the survey, European oral microbiology laboratories process a significant (mean per laboratory 4,135) number of diagnostic samples from the oral cavity annually. A majority of the laboratories did not participate in any internal or external QC programme and nearly half of the laboratories did not have standard operating procedures for the tests they performed. In both QC rounds, there was a large variation in the results, interpretation and reporting of antibiotic susceptibility testing among the laboratories. In conclusion, the results of this study demonstrate the need for harmonisation of laboratory processing methods and interpretation of results for oral microbiology specimens. The QC rounds highlighted the value of external QC in evaluating the efficacy and safety of processes, materials and methods used in the laboratory. The use of standardised methods is also a prerequisite for multi-centre epidemiological studies that can provide important information on emerging microbes and trends in anti-microbial susceptibility for empirical prescribing in oro-facial infections. PMID:22084647

  10. Introducing Quality Control in the Chemistry Teaching Laboratory Using Control Charts

    ERIC Educational Resources Information Center

    Schazmann, Benjamin; Regan, Fiona; Ross, Mary; Diamond, Dermot; Paull, Brett

    2009-01-01

    Quality control (QC) measures are less prevalent in teaching laboratories than commercial settings possibly owing to a lack of commercial incentives or teaching resources. This article focuses on the use of QC assessment in the analytical techniques of high performance liquid chromatography (HPLC) and ultraviolet-visible spectroscopy (UV-vis) at…

  11. ASVCP quality assurance guidelines: control of general analytical factors in veterinary laboratories.

    PubMed

    Flatland, Bente; Freeman, Kathy P; Friedrichs, Kristen R; Vap, Linda M; Getzy, Karen M; Evans, Ellen W; Harr, Kendal E

    2010-09-01

    Owing to lack of governmental regulation of veterinary laboratory performance, veterinarians ideally should demonstrate a commitment to self-monitoring and regulation of laboratory performance from within the profession. In response to member concerns about quality management in veterinary laboratories, the American Society for Veterinary Clinical Pathology (ASVCP) formed a Quality Assurance and Laboratory Standards (QAS) committee in 1996. This committee recently published updated and peer-reviewed Quality Assurance Guidelines on the ASVCP website. The Quality Assurance Guidelines are intended for use by veterinary diagnostic laboratories and veterinary research laboratories that are not covered by the US Food and Drug Administration Good Laboratory Practice standards (Code of Federal Regulations Title 21, Chapter 58). The guidelines have been divided into 3 reports on 1) general analytic factors for veterinary laboratory performance and comparisons, 2) hematology and hemostasis, and 3) clinical chemistry, endocrine assessment, and urinalysis. This report documents recommendations for control of general analytical factors within veterinary clinical laboratories and is based on section 2.1 (Analytical Factors Important In Veterinary Clinical Pathology, General) of the newly revised ASVCP QAS Guidelines. These guidelines are not intended to be all-inclusive; rather, they provide minimum guidelines for quality assurance and quality control for veterinary laboratory testing. It is hoped that these guidelines will provide a basis for laboratories to assess their current practices, determine areas for improvement, and guide continuing professional development and education efforts. PMID:21054473

  12. Computerized real-time quality control program for analytical chemistry laboratories

    SciTech Connect

    Dill, M.S.; Floyd, M.A.; Morrow, R.W.

    1985-10-01

    A unique computer program has been developed for complete quality control/quality assurance of the operation and statistical control of the testing in the analytical laboratory. The system operates similar to a scanner on a production line with effective checkpoints and furnishes immediate feedback by automatically generated mail messages to appropriate personnel when any non-conformance is encountered. Corrective action is required by the technician prior to proceeding with the analysis.

  13. Analytical laboratory quality audits

    SciTech Connect

    Kelley, William D.

    2001-06-11

    Analytical Laboratory Quality Audits are designed to improve laboratory performance. The success of the audit, as for many activities, is based on adequate preparation, precise performance, well documented and insightful reporting, and productive follow-up. Adequate preparation starts with definition of the purpose, scope, and authority for the audit and the primary standards against which the laboratory quality program will be tested. The scope and technical processes involved lead to determining the needed audit team resources. Contact is made with the auditee and a formal audit plan is developed, approved and sent to the auditee laboratory management. Review of the auditee's quality manual, key procedures and historical information during preparation leads to better checklist development and more efficient and effective use of the limited time for data gathering during the audit itself. The audit begins with the opening meeting that sets the stage for the interactions between the audit team and the laboratory staff. Arrangements are worked out for the necessary interviews and examination of processes and records. The information developed during the audit is recorded on the checklists. Laboratory management is kept informed of issues during the audit so there are no surprises at the closing meeting. The audit report documents whether the management control systems are effective. In addition to findings of nonconformance, positive reinforcement of exemplary practices provides balance and fairness. Audit closure begins with receipt and evaluation of proposed corrective actions from the nonconformances identified in the audit report. After corrective actions are accepted, their implementation is verified. Upon closure of the corrective actions, the audit is officially closed.

  14. Performance of automated slidemakers and stainers in a working laboratory environment - routine operation and quality control.

    PubMed

    Simson, E; Gascon-Lema, M G; Brown, D L

    2010-02-01

    The automated slidemaker/stainers of the four Beckman Coulter LH755 hematology systems in our laboratory are operated as analyzers, with similar requirements for setup, maintenance and quality control. A study was performed to confirm that these slide maker/stainers in routine use produce peripheral blood films that are completely satisfactory for microscopy and without cells, particularly abnormal cells, being pulled to the edges or sides of the film outside the usual working area. One hundred and thirty-nine automated blood films that had been produced during routine operation were compared with well-prepared manual films from the same patients. None of the films was unacceptable for microscopy. The distributions of normal white cell types within the counting areas of automated films compared with manual films, for all 139 samples for WBC from 1.0 to 352.8 x 10(9)/l; for blasts and promyelocytes in the 65 samples in which they occurred and for nucleated red blood cells in the 58 samples in which they occurred all fell within the expected limits of 200 cell differential counts of CLSI H20-A. Red cell morphology and the occurrence of WBC clumps, platelet clumps and smudge cells were comparable between the automated and manual films of all samples. We conclude that automated slidemaker/stainers, as typified by those of the Beckman Coulter LH755 system, are capable of producing blood films comparable with well-prepared manual films in routine laboratory use; and that the maintenance and quality control procedures used in our laboratory ensure consistent high quality performance from these systems. PMID:19220552

  15. The Hazardous-Drums Project: A Multiweek Laboratory Exercise for General Chemistry Involving Environmental, Quality Control, and Cost Evaluation

    ERIC Educational Resources Information Center

    Hayes, David; Widanski, Bozena

    2013-01-01

    A laboratory experiment is described that introduces students to "real-world" hazardous waste management issues chemists face. The students are required to define an analytical problem, choose a laboratory analysis method, investigate cost factors, consider quality-control issues, interpret the meaning of results, and provide management…

  16. QUALITY CONTROLS FOR PCR

    EPA Science Inventory

    The purpose of this presentation is to present an overview of the quality control (QC) sections of a draft EPA document entitled, "Quality Assurance/Quality Control Guidance for Laboratories Performing PCR Analyses on Environmental Samples." This document has been prepared by th...

  17. Laboratory Evolution of Fast-Folding Green Fluorescent Protein Using Secretory Pathway Quality Control

    PubMed Central

    Fisher, Adam C.; DeLisa, Matthew P.

    2008-01-01

    Green fluorescent protein (GFP) has undergone a long history of optimization to become one of the most popular proteins in all of cell biology. It is thermally and chemically robust and produces a pronounced fluorescent phenotype when expressed in cells of all types. Recently, a superfolder GFP was engineered with increased resistance to denaturation and improved folding kinetics. Here we report that unlike other well-folded variants of GFP (e.g., GFPmut2), superfolder GFP was spared from elimination when targeted for secretion via the SecYEG translocase. This prompted us to hypothesize that the folding quality control inherent to this secretory pathway could be used as a platform for engineering similar ‘superfolded’ proteins. To test this, we targeted a combinatorial library of GFPmut2 variants to the SecYEG translocase and isolated several superfolded variants that accumulated in the cytoplasm due to their enhanced folding properties. Each of these GFP variants exhibited much faster folding kinetics than the parental GFPmut2 protein and one of these, designated superfast GFP, folded at a rate that even exceeded superfolder GFP. Remarkably, these GFP variants exhibited little to no loss in specific fluorescence activity relative to GFPmut2, suggesting that the process of superfolding can be accomplished without altering the proteins' normal function. Overall, we demonstrate that laboratory evolution combined with secretory pathway quality control enables sampling of largely unexplored amino-acid sequences for the discovery of artificial, high-performance proteins with properties that are unparalleled in their naturally occurring analogues. PMID:18545653

  18. Reliability of nucleic acid amplification for detection of Mycobacterium tuberculosis: an international collaborative quality control study among 30 laboratories.

    PubMed Central

    Noordhoek, G T; van Embden, J D; Kolk, A H

    1996-01-01

    Nucleic acid amplification to detect Mycobacterium tuberculosis in clinical specimens is increasingly used as a laboratory tool for the diagnosis of tuberculosis. However, the specificity and sensitivity of these tests may be questioned, and no standardized reagents for quality control assessment are available. To estimate the performance of amplification tests for routine diagnosis, we initiated an interlaboratory study involving 30 laboratories in 18 countries. We prepared blinded panels of 20 sputum samples containing no, 100, or 1,000 mycobacterial cells. Each laboratory was asked to detect M. tuberculosis by their routine method of nucleic acid amplification. Only five laboratories correctly identified the presence or absence of mycobacterial DNA in all 20 samples. Seven laboratories detected mycobacterial DNA in all positive samples, and 13 laboratories correctly reported the absence of DNA in the negative samples. Lack of specificity was more of a problem than lack of sensitivity. Reliability was not found to be associated with the use of any particular method. Reliable detection of M. tuberculosis in clinical samples by nucleic acid amplification techniques is possible, but many laboratories do not use adequate quality controls. This study underlines the need for good laboratory practice and reference reagents to monitor the performance of the whole assay, including pretreatment of clinical samples. PMID:8880513

  19. Statistical quality control procedures.

    PubMed

    Westgard, James O

    2013-03-01

    The right quality control (QC) should ensure the detection of important errors. Statistical QC (SQC) should be included in all QC plans. The Clinical and Laboratory Standards Institute (CLSI) C24A3 provides guidance for the application of SQC in medical laboratories. It describes a QC planning process and provides an SQC selection tool that relates the sigma-metric of a testing process to the medically important systematic error and the rejection characteristics of different SQC procedures. Once the right SQC has been selected, the laboratory must implement SQC right. CLSI C24A3 also provides guidance for establishing run length and control limits. PMID:23331732

  20. 10 CFR 26.167 - Quality assurance and quality control.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 1 2013-01-01 2013-01-01 false Quality assurance and quality control. 26.167 Section 26.167 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Laboratories Certified by the Department of Health and Human Services § 26.167 Quality assurance and quality control. (a) Quality assurance program. Each HHS-certified laboratory...

  1. 10 CFR 26.167 - Quality assurance and quality control.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 1 2014-01-01 2014-01-01 false Quality assurance and quality control. 26.167 Section 26.167 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Laboratories Certified by the Department of Health and Human Services § 26.167 Quality assurance and quality control. (a) Quality assurance program. Each HHS-certified laboratory...

  2. 21 CFR 111.110 - What quality control operations are required for laboratory operations associated with the...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...CONSUMPTION CURRENT GOOD MANUFACTURING PRACTICE IN MANUFACTURING, PACKAGING, LABELING, OR HOLDING OPERATIONS FOR DIETARY SUPPLEMENTS Production and Process Control System: Requirements for Quality Control § 111.110 What quality...

  3. 21 CFR 111.110 - What quality control operations are required for laboratory operations associated with the...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...CONSUMPTION CURRENT GOOD MANUFACTURING PRACTICE IN MANUFACTURING, PACKAGING, LABELING, OR HOLDING OPERATIONS FOR DIETARY SUPPLEMENTS Production and Process Control System: Requirements for Quality Control § 111.110 What quality...

  4. 21 CFR 111.110 - What quality control operations are required for laboratory operations associated with the...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...CONSUMPTION CURRENT GOOD MANUFACTURING PRACTICE IN MANUFACTURING, PACKAGING, LABELING, OR HOLDING OPERATIONS FOR DIETARY SUPPLEMENTS Production and Process Control System: Requirements for Quality Control § 111.110 What quality...

  5. Automation and quality in analytical laboratories

    SciTech Connect

    Valcarcel, M.; Rios, A.

    1994-05-01

    After a brief introduction to the generic aspects of automation in analytical laboratories, the different approaches to quality in analytical chemistry are presented and discussed to establish the following different facets emerging from the combination of quality and automation: automated analytical control of quality of products and systems; quality control of automated chemical analysis; and improvement of capital (accuracy and representativeness), basic (sensitivity, precision, and selectivity), and complementary (rapidity, cost, and personnel factors) analytical features. Several examples are presented to demonstrate the importance of this marriage of convenience in present and future analytical chemistry. 7 refs., 4 figs.

  6. Quality assurance and quality control in light stable isotope laboratories: A case study of Rio Grande, Texas, water samples

    USGS Publications Warehouse

    Coplen, T.B.; Qi, H.

    2009-01-01

    New isotope laboratories can achieve the goal of reporting the same isotopic composition within analytical uncertainty for the same material analysed decades apart by (1) writing their own acceptance testing procedures and putting them into their mass spectrometric or laser-based isotope-ratio equipment procurement contract, (2) requiring a manufacturer to demonstrate acceptable performance using all sample ports provided with the instrumentation, (3) for each medium to be analysed, prepare two local reference materials substantially different in isotopic composition to encompass the range in isotopic composition expected in the laboratory and calibrated them with isotopic reference materials available from the International Atomic Energy Agency (IAEA) or the US National Institute of Standards and Technology (NIST), (4) using the optimum storage containers (for water samples, sealing in glass ampoules that are sterilised after sealing is satisfactory), (5) interspersing among sample unknowns local laboratory isotopic reference materials daily (internationally distributed isotopic reference materials can be ordered at three-year intervals, and can be used for elemental analyser analyses and other analyses that consume less than 1 mg of material) - this process applies to H, C, N, O, and S isotope ratios, (6) calculating isotopic compositions of unknowns by normalising isotopic data to that of local reference materials, which have been calibrated to internationally distributed isotopic reference materials, (7) reporting results on scales normalised to internationally distributed isotopic reference materials (where they are available) and providing to sample submitters the isotopic compositions of internationally distributed isotopic reference materials of the same substance had they been analysed with unknowns, (8) providing an audit trail in the laboratory for analytical results - this trail commonly will be in electronic format and might include a laboratory information management system, (9) making at regular intervals a complete backup of laboratory analytical data (both of samples logged into the laboratory and of mass spectrometric analyses), being sure to store one copy of this backup offsite, and (10) participating in interlaboratory comparison exercises sponsored by the IAEA and other agencies at regular intervals. ?? Taylor & Francis.

  7. Effect of leachate recirculation on landfill gas production and leachate quality: A controlled laboratory study

    SciTech Connect

    Bogner, J.; Spokas, K.

    1995-05-01

    This report summarizes the results of a laboratory study conducted during 1992-1994 at Argonne National Laboratory. The study examined biogas production and leachate chemistry in parallel anaerobic assays run under either leachate recycle or leachate drainage regimes over a period of 400 days. A standardized synthetic refuse (paper, grass, food) was used in an experimental design which evaluated two elevated moisture contents and two added soils. All assays were conducted in vitro in 125 mL serum bottles. Four recycle/drainage events were completed during the 400 days of this experiment. Sufficient replicates (10 or 20) for each trial were included in the experimental design to permit destructive sampling of assay solids after each recycle/drainage event. Changes in the chemistry of solid, liquid, and gaseous phases were evaluated during the decomposition process. Analyses included major gases (CH{sub 4}, CO{sub 2}, O{sub 2}, N{sub 2}), selected chemical constituents of leachate (Cl-C5 carboxylic acids, total organic carbon, Kjeldahl nitrogen, total phosphorus, iron, zinc, and chloride), leachate pH and conductivity, and selected solids analysis (gravimetric moisture content, volatile solids, total carbon, cellulose, hemicellulose, and lignin).

  8. 21 CFR 111.110 - What quality control operations are required for laboratory operations associated with the...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 2 2011-04-01 2011-04-01 false What quality control operations are required for... and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR... OPERATIONS FOR DIETARY SUPPLEMENTS Production and Process Control System: Requirements for Quality...

  9. 21 CFR 111.110 - What quality control operations are required for laboratory operations associated with the...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What quality control operations are required for... and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR... OPERATIONS FOR DIETARY SUPPLEMENTS Production and Process Control System: Requirements for Quality...

  10. Quality Control Introduction

    E-print Network

    Vickers, James

    Quality Control 46.2 Introduction Quality control via the use of statistical methods is a very successful at applying statistical methods to industrial quality control and have gained a significant become. It is because of the global nature of modern industrial competition that quality control, or more

  11. NCI-Frederick PHL - Quality Control

    Cancer.gov

    An important aspect of our work is the Quality Control of the material before it is released from the laboratory. The Quality Control department microscopically reviews materials produced by the histology laboratory to ensure they meet or exceed PHL’s established level of excellence. Materials with any defect are returned to the laboratory to be repeated, at no additional cost to the investigator.

  12. Quality Assurance Program for Molecular Medicine Laboratories

    PubMed Central

    Hajia, M; Safadel, N; Samiee, S Mirab; Dahim, P; Anjarani, S; Nafisi, N; Sohrabi, A; Rafiee, M; Sabzavi, F; Entekhabi, B

    2013-01-01

    Background: Molecular diagnostic methods have played and continuing to have a critical role in clinical laboratories in recent years. Therefore, standardization is an evolutionary process that needs to be upgrade with increasing scientific knowledge, improvement of the instruments and techniques. The aim of this study was to design a quality assurance program in order to have similar conditions for all medical laboratories engaging with molecular tests. Methods: We had to design a plan for all four elements; required space conditions, equipments, training, and basic guidelines. Necessary guidelines was prepared and confirmed by the launched specific committee at the Health Reference Laboratory. Results: Several workshops were also held for medical laboratories directors and staffs, quality control manager of molecular companies, directors and nominees from universities. Accreditation of equipments and molecular material was followed parallel with rest of program. Now we are going to accredit medical laboratories and to evaluate the success of the program. Conclusion: Accreditation of medical laboratory will be succeeding if its basic elements are provided in advance. Professional practice guidelines, holding training and performing accreditation the molecular materials and equipments ensured us that laboratories are aware of best practices, proper interpretation, limitations of techniques, and technical issues. Now, active external auditing can improve the applied laboratory conditions toward the defined standard level. PMID:23865028

  13. [Total quality management in laboratory medicine].

    PubMed

    Vogt, W

    1998-12-01

    The German Public Health will be continuously challenged in the future. It has to be assumed that modified managed care will not only take place sporadically. Thus, quality aspects of services gain more and more significance. Only suppliers will be successful who can offer services of highest quality at lowest prices. Quality in a comprehensive sense has to be substantiated in the near future. It is recommended to apply industry proven models also in public health service. Medical laboratories can be pioneers in this field as they have been already in the past. All previously proposed procedures can not describe quality of results comprehensively. They are based to a high degree on external control. Total quality management, however, represents a comprehensive approach. Principles are zero-defect approach, customer orientation and system management. Quality is given in the sense of TQM if the customer is permanently satisfied with the service of the supplier. In such a way, the customer defines quality of service. A customer is everyone who receives products or services. TQM overcomes the drawbacks of quality management systems, which are strongly formal and oriented by external control, as accreditation (EN 45,000) or certification (ISO 9000). Competition between hospitals is a declared goal of German health politics because usually quality is increased and cost decreased as a consequence. Competition means also comparison of services. TQM emphasizes benchmarking especially among the best suppliers. PMID:10028601

  14. Dietary Supplement Laboratory Quality Assurance Program

    E-print Network

    Dietary Supplement Laboratory Quality Assurance Program: Exercise H Final Report Melissa M://dx.doi.org/10.6028/NIST.IR.7903 NISTIR 7903 #12;ii Dietary Supplement Laboratory Quality Assurance Program Supplement Laboratory Quality Assurance Program: Exercise H Final Report Melissa M. Phillips Catherine A

  15. Quality Leadership and Quality Control

    PubMed Central

    Badrick, Tony

    2003-01-01

    Different quality control rules detect different analytical errors with varying levels of efficiency depending on the type of error present, its prevalence and the number of observations. The efficiency of a rule can be gauged by inspection of a power function graph. Control rules are only part of a process and not an end in itself; just as important are the trouble-shooting systems employed when a failure occurs. 'Average of patient normals' may develop as a usual adjunct to conventional quality control serum based programmes. Acceptable error can be based on various criteria; biological variation is probably the most sensible. Once determined, acceptable error can be used as limits in quality control rule systems. A key aspect of an organisation is leadership, which links the various components of the quality system. Leadership is difficult to characterise but its key aspects include trust, setting an example, developing staff and critically setting the vision for the organisation. Organisations also have internal characteristics such as the degree of formalisation, centralisation, and complexity. Medical organisations can have internal tensions because of the dichotomy between the bureaucratic and the shadow medical structures. PMID:18568046

  16. THE DATABASE AN ELECTRONIC ENHANCEMENT TO LABORATORY QUALITY ASSURANCE

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The Quality Control program of an analytical laboratory is a key component in support of a research or compliance laboratory because it provides objective evidence for certified results. The recent addition of a customized, computerized database to our analytical laboratory has improved many aspect...

  17. Indoor Air Quality in Chemistry Laboratories.

    ERIC Educational Resources Information Center

    Hays, Steve M.

    This paper presents air quality and ventilation data from an existing chemical laboratory facility and discusses the work practice changes implemented in response to deficiencies in ventilation. General methods for improving air quality in existing laboratories are presented and investigation techniques for characterizing air quality are…

  18. The Human Monitoring Laboratory's whole body counter: monitoring the liquid nitrogen level as a quality control tool.

    PubMed

    Kramer, Gary H; Hauck, Barry M

    2007-11-01

    The Human Monitoring Laboratory (HML) has developed a method to measure the liquid nitrogen boil-off rate from the whole body counter's single dewar as a function of time. The device consists of a commercially available instrument that was modified to fit the HML's whole body counter's dewar; unfortunately, the modification was not perfect requiring an alternative approach to using the maximum fill value. The boil-off rate is now measured by taking two measurements and calculating the loss rate. Resulting boil-off rates are plotted on a control chart so that long-term trends can be easily assessed. PMID:18049247

  19. Laboratory 11 Control Systems Laboratory ECE3557 Laboratory 11

    E-print Network

    for Position Control of a Flexible Joint 11.1 Objective The objective of this laboratory is to design a full in this laboratory is illustrated. For this laboratory, the servo is used in the high gear ratio configuration (refer = 2.6 · Km: one of the motor torque constants. Km = 0.00767 · Kg: gear ratio of the motor

  20. Perspectives on quality control, risk management, and analytical quality management.

    PubMed

    Westgard, James O

    2013-03-01

    Quality control (QC) practices are changing in US laboratories as Centers for Medicare and Medicaid Services adopts individualized QC plans as a new option for compliance with the Clinical Laboratory Improvement Amendments regulations. The Joint Commission provides general guidance for applying risk management in health care organizations. The EP23A (Evaluation Protocol 23A) document from the Clinical and Laboratory Standards Institute provides specific guidance on the use of risk management for developing analytical QC plans. Medical laboratories should integrate risk management tools with existing quality management techniques and activities to provide an overall plan for analytical quality management. PMID:23331725

  1. Quality Control in Mammography

    NASA Astrophysics Data System (ADS)

    Noel, Alain

    In mammography to obtain the best image quality at the lower possible dose to minimize the risk, implementation of an effective quality control protocol is of the utmost importance. This paper will mainly review quality control (QC) procedures for screen-film mammography and will briefly present how screen-film and digital differ. Finally, the possibility to automate some tests in digital mammography will be introduced.

  2. 1990 National Water Quality Laboratory Services Catalog

    USGS Publications Warehouse

    Pritt, Jeffrey, (Edited By); Jones, Berwyn E.

    1989-01-01

    PREFACE This catalog provides information about analytical services available from the National Water Quality Laboratory (NWQL) to support programs of the Water Resources Division of the U.S. Geological Survey. To assist personnel in the selection of analytical services, the catalog lists cost, sample volume, applicable concentration range, detection level, precision of analysis, and preservation techniques for samples to be submitted for analysis. Prices for services reflect operationa1 costs, the complexity of each analytical procedure, and the costs to ensure analytical quality control. The catalog consists of five parts. Part 1 is a glossary of terminology; Part 2 lists the bottles, containers, solutions, and other materials that are available through the NWQL; Part 3 describes the field processing of samples to be submitted for analysis; Part 4 describes analytical services that are available; and Part 5 contains indices of analytical methodology and Chemical Abstract Services (CAS) numbers. Nomenclature used in the catalog is consistent with WATSTORE and STORET. The user is provided with laboratory codes and schedules that consist of groupings of parameters which are measured together in the NWQL. In cases where more than one analytical range is offered for a single element or compound, different laboratory codes are given. Book 5 of the series 'Techniques of Water Resources Investigations of the U.S. Geological Survey' should be consulted for more information about the analytical procedures included in the tabulations. This catalog supersedes U.S. Geological Survey Open-File Report 86-232 '1986-87-88 National Water Quality Laboratory Services Catalog', October 1985.

  3. Dietary Supplement Laboratory Quality Assurance Program

    E-print Network

    Dietary Supplement Laboratory Quality Assurance Program: Exercise J Final Report Melissa M.6028/NIST.IR.7997 NISTIR 7997 #12;Dietary Supplement Laboratory Quality Assurance Program: Exercise F Final Assurance Program: Exercise J Final Report Melissa M. Phillips Catherine A. Rimmer Laura J. Wood Mary Bedner

  4. QUALITY CONTROL - VARIABILITY IN PROTOCOLS

    EPA Science Inventory

    The EPA Risk Reduction Engineering Laboratory’s Quality Assurance Office, which published the popular pocket guide Preparing Perfect Project Plans, is now introducing another quality assurance reference aid. The document Variability in Protocols (VIP) was initially designed as a ...

  5. Methods of analysis by the U.S. Geological Survey National Water Quality Laboratory; processing, taxonomy, and quality control of benthic macroinvertebrate samples

    USGS Publications Warehouse

    Moulton, Stephen R., II; Carter, James L.; Grotheer, Scott A.; Cuffney, Thomas F.; Short, Terry M.

    2000-01-01

    Qualitative and quantitative methods to process benthic macroinvertebrate (BMI) samples have been developed and tested by the U.S. Geological Survey?s National Water Quality Laboratory Biological Group. The qualitative processing method is based on visually sorting a sample for up to 2 hours. Sorting focuses on attaining organisms that are likely to result in taxonomic identifications to lower taxonomic levels (for example, Genus or Species). Immature and damaged organisms are also sorted when they are likely to result in unique determinations. The sorted sample remnant is scanned briefly by a second person to determine if obvious taxa were missed. The quantitative processing method is based on a fixed-count approach that targets some minimum count, such as 100 or 300 organisms. Organisms are sorted from randomly selected 5.1- by 5.1-centimeter parts of a gridded subsampling frame. The sorted remnant from each sample is resorted by a second individual for at least 10 percent of the original sort time. A large-rare organism search is performed on the unsorted remnant to sort BMI taxa that were not likely represented in the sorted grids. After either qualitatively or quantitatively sorting the sample, BMIs are identified by using one of three different types of taxonomic assessment. The Standard Taxonomic Assessment is comparable to the U.S. Environmental Protection Agency Rapid Bioassessment Protocol III and typically provides Genus- or Species-level taxonomic resolution. The Rapid Taxonomic Assessment is comparable to the U.S. Environmental Protection Agency Rapid Bioassessment Protocol II and provides Familylevel and higher taxonomic resolution. The Custom Taxonomic Assessment provides Species-level resolution whenever possible for groups identified to higher taxonomic levels by using the Standard Taxonomic Assessment. The consistent use of standardized designations and notes facilitates the interpretation of BMI data within and among water-quality studies. Taxonomic identifications are quality assured by verifying all referenced taxa and randomly reviewing 10 percent of the taxonomic identifications performed weekly by Biological Group taxonomists. Taxonomic errors discovered during this review are corrected. BMI data are reviewed for accuracy and completeness prior to release. BMI data are released phylogenetically in spreadsheet format and unprocessed abundances are corrected for laboratory and field subsampling when necessary.

  6. Evaluation of Quality-Assurance/Quality-Control Data Collected by the U.S. Geological Survey from Wells and Springs between the Southern Boundary of the Idaho National Engineering and Environmental Laboratory and the Hagerman Area, Idaho, 1989 through 1995

    SciTech Connect

    Williams, L.M.; Bartholomay, R.C.; Campbell, L.J.

    1998-10-01

    The U.S. Geological (USGS) and the Idaho Department of Water Resources, in cooperation with the U.S. Department of Energy, collected and analyzed water samples to monitor the water quality of the Snake River Plain aquifer from the southern boundary of the Idaho National Engineering and Environmental Laboratory to the Hagerman area, Idaho. Concurrently, replicate samples and blank samples were collected and analyzed as part of the quality-assurance/quality-control program. Samples were analyzed from inorganic constituents, gross radioactivity and radionuclides, organic constituents, and stable isotopes. To evaluate the precision of field and laboratory methods, analytical results of the water-quality and replicate samples were compared statistically for equivalence on the basis of the precision associated with each result. Statistical comparisons of the data indicated that 95 percent of the results of the replicate pairs were equivalent. Blank-sample analytical results indicated th at the inorganic blank water and volatile organic compound blank water from the USGS National Water Quality Laboratory and the distilled water from the Idaho Department of Water Resources were suitable for blanks; blank water from other sources was not. Equipment-blank analytical results were evaluated to determine if a bias had been introduced and possible sources of bias. Most equipment blanks were analyzed for trace elements and volatile organic compounds; chloroform was found in one equipment blank. Two of the equipment blanks were prepared after collection and analyses of the water-quality samples to determine whether contamination had been introduced during the sampling process. Results of one blank indicated that a hose used to divert water away from pumps and electrical equipment had contaminated the samples with some volatile organic compounds. Results of the other equipment blank, from the apparatus used to filter dissolved organic carbon samples, indicated that the filtering apparatus did not affect water-quality samples.

  7. 21 CFR 606.140 - Laboratory controls.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 2011-04-01 2010-04-01 true Laboratory controls. 606.140 Section 606.140...MANUFACTURING PRACTICE FOR BLOOD AND BLOOD COMPONENTS Laboratory Controls § 606.140 Laboratory controls. Laboratory control...

  8. On the use of (127)Xe standards for the quality control of CTBTO noble gas stations and support laboratories.

    PubMed

    Cagniant, A; Le Petit, G; Nadalut, B; Gross, P; Richard-Bressand, H; Fontaine, J-P; Douysset, G

    2014-07-01

    (127)Xe has a longer half-life than (131m)Xe, it can be easily purely produced and it is present in the environment at very low level. For these reasons, (127)Xe is supposed to be a convenient quality control radionuclide for remote noble gas stations of the International Monitoring System (IMS) network. As CEA/DAM has recently developed two new photon/electron setups for low-level detection of (131m)Xe, (133m)Xe, (133)Xe and (135)Xe, we took the opportunity to test these setups for the measurement of a (127)Xe standard. The results and a detailed description of these measurements are presented in this paper. They illustrate the complexity of (127)Xe decay, emitting simultaneously several ?, X-rays, conversion electrons and Auger electrons; this results in highly summated coincidence spectra. The measurements performed provide precise electron energy calibration of the setups. The count rate of electrons in coincidence with iodine K? X-rays was found to be surprisingly low, leading to the study of electron-gated photon spectrum. Finally, a comparison of three photon/electron coincidence spectra obtained with three different setups is given. The use of (127)Xe as a standard for energy calibration of IMS noble gas station is possible, but it appears to be quite complicated for efficiency check of noble gas station equipped with ?/? detectors. PMID:24657473

  9. Quality control tests of lab-reared Cydia pomonella and Cactoblastis cactorum field performance: Comparison of laboratory and field bioassays.

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Research, operational, and commercial programs which rely on mass-reared insects of high quality and performance, need accurate methods for monitoring quality degradation during each step of production, handling and release. With continued interest in the use of the sterile insect technique (SIT) a...

  10. 21 CFR 111.110 - What quality control operations are required for laboratory operations associated with the...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...associated with the production and process control system? 111.110...CONSUMPTION CURRENT GOOD MANUFACTURING PRACTICE IN MANUFACTURING, PACKAGING, LABELING...SUPPLEMENTS Production and Process Control System:...

  11. Facilitating quality control for spectra assignments of small organic molecules: nmrshiftdb2--a free in-house NMR database with integrated LIMS for academic service laboratories.

    PubMed

    Kuhn, Stefan; Schlörer, Nils E

    2015-08-01

    nmrshiftdb2 supports with its laboratory information management system the integration of an electronic lab administration and management into academic NMR facilities. Also, it offers the setup of a local database, while full access to nmrshiftdb2's World Wide Web database is granted. This freely available system allows on the one hand the submission of orders for measurement, transfers recorded data automatically or manually, and enables download of spectra via web interface, as well as the integrated access to prediction, search, and assignment tools of the NMR database for lab users. On the other hand, for the staff and lab administration, flow of all orders can be supervised; administrative tools also include user and hardware management, a statistic functionality for accounting purposes, and a 'QuickCheck' function for assignment control, to facilitate quality control of assignments submitted to the (local) database. Laboratory information management system and database are based on a web interface as front end and are therefore independent of the operating system in use. PMID:25998807

  12. Emerging concepts of quality assurance in clinical laboratories.

    PubMed

    Naz, Sumera; Saddar-ud-din, Agha

    2006-09-01

    Quality Assurance is a management system designed to achieve an acceptable level of quality services, prevent poor quality and in laboratories is intended to ensure reliability of results. It comprehensively includes controlling the quality of procedures at each and every step including Pre-analytical (specimen collection and transport), Analytical (specimen processing in the lab) and Post-analytical (reporting and interpretation of results). Concept of total quality management (TQM) is closely interlinked with good laboratory practices and goes far beyond the widely practiced conventional Quality Control (QC) procedures. TQM includes Technical accuracy and precision, equipment and supplies, staff training and skill, financial management (cost effectiveness), lab safety, communication etc. Recent pressures on pathology laboratories have meant that laboratories no longer have the numbers of scientists and pathologists they had in the past. This has resulted in more questions being asked of the QA staff with a steady increase in the number of scientists employed to address this demand. Quality improvement in the modern clinical laboratory environment entails the continuous inspection and refinement of processes to ensure the efficient delivery of services that meet the needs and expectations of those who use them. PMID:17091755

  13. Total quality management in clinical virology laboratories.

    PubMed

    Tibbets, M W; Gomez, R; Kannangai, R; Sridharan, G

    2006-10-01

    The diagnostic laboratories in India are progressively promoting higher standards and are moving towards accreditation and international acceptance. Hence, the concept of "Quality" will need to be understood and implemented. Total quality management (TQM) in a laboratory is an integrated program involving all laboratory staff and management. TQM is a framework to operate and it is aiming for integration, consistency, increase in efficiency and a continuous drive for improvement. A well structured clinical virology service will include serology setup, cell culture facility and capacity for molecular diagnosis. The quality of results from the laboratory is significantly influenced by many pre-analytical and post-analytical factors which needed attention. The end goal of the TQM should be to provide the best care possible for the patient. PMID:17185843

  14. Quality control review: implementing a scientifically based quality control system.

    PubMed

    Westgard, James O; Westgard, Sten A

    2016-01-01

    This review focuses on statistical quality control in the context of a quality management system. It describes the use of a 'Sigma-metric' for validating the performance of a new examination procedure, developing a total quality control strategy, selecting a statistical quality control procedure and monitoring ongoing quality on the sigma scale. Acceptable method performance is a prerequisite to the design and implementation of statistical quality control procedures. Statistical quality control can only monitor performance, and when properly designed, alert analysts to the presence of additional errors that occur because of unstable performance. A new statistical quality control planning tool, called 'Westgard Sigma Rules,' provides a simple and quick way for selecting control rules and the number of control measurements needed to detect medically important errors. The concept of a quality control plan is described, along with alternative adaptations of a total quality control plan and a risk-based individualized quality control plan. Finally, the ongoing monitoring of analytic performance and test quality are discussed, including determination of measurement uncertainty from statistical quality control data collected under intermediate precision conditions and bias determined from proficiency testing/external quality assessment surveys. A new graphical tool, called the Sigma Quality Assessment Chart, is recommended for demonstrating the quality of current examination procedures on the sigma scale. PMID:26150675

  15. Quality Control Technician.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Center on Education and Training for Employment.

    This document contains 18 units to consider for use in a tech prep competency profile for the occupation of quality control technician. All the units listed will not necessarily apply to every situation or tech prep consortium, nor will all the competencies within each unit be appropriate. Several units appear within each specific occupation and…

  16. 7 CFR 90.103 - Maintenance of quality control records.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 3 2013-01-01 2013-01-01 false Maintenance of quality control records. 90.103 Section... LABORATORY TESTING PROGRAMS INTRODUCTION Quality Assurance § 90.103 Maintenance of quality control records. Quality control records pertaining, but not limited to the following areas, shall be retained by...

  17. 7 CFR 90.103 - Maintenance of quality control records.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 3 2014-01-01 2014-01-01 false Maintenance of quality control records. 90.103 Section... LABORATORY TESTING PROGRAMS INTRODUCTION Quality Assurance § 90.103 Maintenance of quality control records. Quality control records pertaining, but not limited to the following areas, shall be retained by...

  18. 7 CFR 90.103 - Maintenance of quality control records.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 3 2012-01-01 2012-01-01 false Maintenance of quality control records. 90.103 Section... LABORATORY TESTING PROGRAMS INTRODUCTION Quality Assurance § 90.103 Maintenance of quality control records. Quality control records pertaining, but not limited to the following areas, shall be retained by...

  19. Vgi Quality Control

    NASA Astrophysics Data System (ADS)

    Fonte, C. C.; Bastin, L.; Foody, G.; Kellenberger, T.; Kerle, N.; Mooney, P.; Olteanu-Raimond, A.-M.; See, L.

    2015-08-01

    This paper presents a framework for considering quality control of volunteered geographic information (VGI). Different issues need to be considered during the conception, acquisition and post-acquisition phases of VGI creation. This includes items such as collecting metadata on the volunteer, providing suitable training, giving corrective feedback during the mapping process and use of control data, among others. Two examples of VGI data collection are then considered with respect to this quality control framework, i.e. VGI data collection by National Mapping Agencies and by the most recent Geo-Wiki tool, a game called Cropland Capture. Although good practices are beginning to emerge, there is still the need for the development and sharing of best practice, especially if VGI is to be integrated with authoritative map products or used for calibration and/or validation of land cover in the future.

  20. LABCON - Laboratory Job Control program

    NASA Technical Reports Server (NTRS)

    Reams, L. T.

    1969-01-01

    Computer program LABCON controls the budget system in a component test laboratory whose workload is made up from many individual budget allocations. A common denominator is applied to an incoming job, to which all effort is charged and accounted for.

  1. Quality control of seasonal influenza vaccines.

    PubMed

    Manduši? Nazor, Tamara; Pipi? Kosanovi?, Marta; Tomi?, Siniša

    2010-12-01

    The purpose of seasonal influenza vaccination is to prevent its spread. The vaccines contain strains of the influenza virus recommended and approved for a particular season. Just like any other medicinal product, all vaccines require marketing approval. Batches of approved vaccines are extensively tested by the manufacturers and additionally controlled by the approving authorities, which issue the quality control certificates. This article not only to describes the legal background of quality control, but also how control test results obtained by a Croatian official control laboratory are compared to manufacturer's results. We have found that testing results can slightly differ depending on methods/analytical procedures used in different laboratories. This investigation has also shown how important it is to test finished medicinal products, independently of testing at intermediate stages, and how retesting by control authorities ensures that marketed vaccines meet quality standards. PMID:21183435

  2. National Water Quality Laboratory, 1994 services catalog

    USGS Publications Warehouse

    Timme, P.J.

    1994-01-01

    This Services Catalog contains information about field supplies and analytical services available from the National Water Quality Laboratory in Denver, Colo., and field supplies available from the Quality Water Service Unit in Ocala, Fla., to members of the U.S. Geological Survey's Water Resources Division. To assist personnel in the selection of analytical services, this catalog lists sample volume, applicable concentration range, detection level, precision of analysis, and preservation requirements for samples. (USGS)

  3. Distribution of U and REE on colloids in granitic groundwater and quality-controlled sampling at the Mizunami underground research laboratory

    NASA Astrophysics Data System (ADS)

    Munemoto, Takashi; Ohmori, Kazuaki; Iwatsuki, Teruki

    2014-12-01

    Colloids and their association with analogue elements, uranium, and rare earth elements (REEs), in deep granitic groundwater were investigated at the Mizunami Underground Research Laboratory (MIU). Groundwater was sampled from underground boreholes and gallery walls, and the colloids were separated by size-fractionated ultrafiltration (pore sizes, 0.2 ?m, 10 kDa, and 1 kDa). For the groundwater sampled from fractures in excavation walls, the size-fractionated concentrations of the colloid-forming elements were approximately constant relative to different size fractions (0.2 ?m, 200 kDa, 50 kDa, and 10 kDa). The contamination of Fe- and Al-bearing materials was insignificant in the filtered groundwater from fracture seepages. Changes in the concentrations of U in the groundwater sampled from boreholes and excavation walls were associated with the Al-bearing colloids, Fe-bearing colloids, and organic matter. The REE-bearing material(s) that were >0.2 ?m in size were mobile in the deep granitic groundwater, rather than occurring in association with Al-bearing, Fe-bearing colloids, and organic matter. It is suggested that sampling from water-conducting fractures in host rock and colloid elimination in borehole are important components of water quality control in geochemical investigations.

  4. Establishing quality control ranges for antimicrobial susceptibility testing of Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus: a cornerstone to develop reference strains for Korean clinical microbiology laboratories.

    PubMed

    Hong, Sung Kuk; Choi, Seung Jun; Shin, Saeam; Lee, Wonmok; Pinto, Naina; Shin, Nari; Lee, Kwangjun; Hong, Seong Geun; Kim, Young Ah; Lee, Hyukmin; Kim, Heejung; Song, Wonkeun; Lee, Sun Hwa; Yong, Dongeun; Lee, Kyungwon; Chong, Yunsop

    2015-11-01

    Quality control (QC) processes are being performed in the majority of clinical microbiology laboratories to ensure the performance of microbial identification and antimicrobial susceptibility testing by using ATCC strains. To obtain these ATCC strains, some inconveniences are encountered concerning the purchase cost of the strains and the shipping time required. This study was focused on constructing a database of reference strains for QC processes using domestic bacterial strains, concentrating primarily on antimicrobial susceptibility testing. Three strains (Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus) that showed legible results in preliminary testing were selected. The minimal inhibitory concentrations (MICs) and zone diameters (ZDs) of eight antimicrobials for each strain were determined according to the CLSI M23. All resulting MIC and ZD ranges included at least 95% of the data. The ZD QC ranges obtained by using the CLSI method were less than 12 mm, and the MIC QC ranges extended no more than five dilutions. This study is a preliminary attempt to construct a bank of Korean QC strains. With further studies, a positive outcome toward cost and time reduction can be anticipated. PMID:26354353

  5. GROUNDWATER QUALITY CONTROL THROUGH GOOD

    E-print Network

    Delaware, University of

    GROUNDWATER QUALITY CONTROL THROUGH GOOD GOVERNANCE A Report for the Science, Engineering Assembly And the University of Delaware #12;Groundwater Quality Control Through Good Governance CEEP Page 1D student Melissa Bollman, MEEP student Christy Bugher, Engineering student #12;Groundwater Quality Control

  6. Evaluation of quality-control data collected by the U.S. Geological Survey for routine water-quality activities at the Idaho National Laboratory and vicinity, southeastern Idaho, 2002-08

    USGS Publications Warehouse

    Rattray, Gordon W.

    2014-01-01

    Quality-control (QC) samples were collected from 2002 through 2008 by the U.S. Geological Survey, in cooperation with the U.S. Department of Energy, to ensure data robustness by documenting the variability and bias of water-quality data collected at surface-water and groundwater sites at and near the Idaho National Laboratory. QC samples consisted of 139 replicates and 22 blanks (approximately 11 percent of the number of environmental samples collected). Measurements from replicates were used to estimate variability (from field and laboratory procedures and sample heterogeneity), as reproducibility and reliability, of water-quality measurements of radiochemical, inorganic, and organic constituents. Measurements from blanks were used to estimate the potential contamination bias of selected radiochemical and inorganic constituents in water-quality samples, with an emphasis on identifying any cross contamination of samples collected with portable sampling equipment. The reproducibility of water-quality measurements was estimated with calculations of normalized absolute difference for radiochemical constituents and relative standard deviation (RSD) for inorganic and organic constituents. The reliability of water-quality measurements was estimated with pooled RSDs for all constituents. Reproducibility was acceptable for all constituents except dissolved aluminum and total organic carbon. Pooled RSDs were equal to or less than 14 percent for all constituents except for total organic carbon, which had pooled RSDs of 70 percent for the low concentration range and 4.4 percent for the high concentration range. Source-solution and equipment blanks were measured for concentrations of tritium, strontium-90, cesium-137, sodium, chloride, sulfate, and dissolved chromium. Field blanks were measured for the concentration of iodide. No detectable concentrations were measured from the blanks except for strontium-90 in one source solution and one equipment blank collected in September and October 2004, respectively. The detectable concentrations of strontium-90 in the blanks probably were from a small source of strontium-90 contamination or large measurement variability, or both. Order statistics and the binomial probability distribution were used to estimate the magnitude and extent of any potential contamination bias of tritium, strontium-90, cesium-137, sodium, chloride, sulfate, dissolved chromium, and iodide in water-quality samples. These statistical methods indicated that, with (1) 87 percent confidence, contamination bias of cesium-137 and sodium in 60 percent of water-quality samples was less than the minimum detectable concentration or reporting level; (2) 92?94 percent confidence, contamination bias of tritium, strontium-90, chloride, sulfate, and dissolved chromium in 70 percent of water-quality samples was less than the minimum detectable concentration or reporting level; and (3) 75 percent confidence, contamination bias of iodide in 50 percent of water-quality samples was less than the reporting level for iodide. These results support the conclusion that contamination bias of water-quality samples from sample processing, storage, shipping, and analysis was insignificant and that cross-contamination of perched groundwater samples collected with bailers during 2002–08 was insignificant.

  7. [The network of official medicines control laboratories].

    PubMed

    Buchheit, K-H; Wanko, R

    2014-10-01

    Licensing, control and surveillance by competent authorities is the basis for ensuring efficacy, safety and quality of medicines in Europe. The control of the quality of medicines by national control laboratories, known as Official Medicines Control Laboratories (OMCLs) is an essential step in this process; it encompasses controls before and after granting a marketing authorisation. For certain groups of biomedical medicines (vaccines for human and veterinary use, medicines derived from human plasma) even each batch is controlled before it can be placed on the market. As single OMCLs would not be able to cope with their task, given the large number and diversity of medicines, in 1994 the OMCL network was founded upon initiative of the European Directorate for the Quality of Medicines & HealthCare, in close collaboration with the Commission of the European Union. Currently 68 OMCLs from 39 countries are part of the network. Prerequisite for the smooth operation of the OMCL network is the harmonisation of the quality management system of the individual OMCLs, based on the ISO 17025 standard, internal guidelines and the European Pharmacopoeia. Compliance with these standards is checked through regular audits, thus creating the basis for mutual recognition of test results. The collaboration in the OMCL network for the surveillance of the medicines market, the official control authority batch release and the fight against counterfeiting and illegal medicines enables OMCLs to keep pace with the developments in the field of medicines and to control the broad spectrum of medicines. In the 20 years since its start, the OMCL network has become a European success story. PMID:25192832

  8. Quality assurance and quality control in clinical cytogenetics.

    PubMed

    Mikhail, Fady M; Watson, Michael S

    2014-01-01

    The goal of any clinical laboratory should be to provide patients with the most accurate test results possible. This is accomplished through various overlapping programs that continuously monitor and optimize all aspects of a test, including decisions by the laboratory to offer a test, the decision of providers to request the test, the testing itself, and the reporting of results to the referral source and patient. The levels at which test performance and accuracy can be optimized are encompassed under quality control (QC) and quality assurance (QA). The monitoring of QC and QA problems allows for the integration of these parameters into a total quality management program. This unit reviews QC and QA guidelines, in addition to discussing how to establish a quality assurance program. Curr. Protoc. Hum. Genet. 82:8.2.1-8.2.10. © 2014 by John Wiley & Sons, Inc. PMID:25042720

  9. Quality Assurance and Quality Control, Part 1.

    PubMed

    Akers, Michael J

    2015-01-01

    The tragedy surrounding the New England Compounding Center and contaminated steroid syringe preparations clearly points out what can happen if quality-assurance and quality-control procedures are not strictly practiced in the compounding of sterile preparations. This article represents part 1 of a 2-part article on quality-assurance and quality-control procedures and serves as an introduction to the topic of finished preparation release checks and tests. Part 1 highlights what is required to comply with United States Pharmacopeia General Chapter <797>, and part 2 continues with a discussion on the requirements of <797> as well as what is required in chapter < 1163> with respect to quality assurance of compounded sterile preparations. Written procedures, good documentation practices, and specific details for clarity, sterility, and bacterial endotoxin (pyrogen) testing are presented in this article. PMID:26685493

  10. CONTROLLING THE QUALITY OF TRAINING.

    ERIC Educational Resources Information Center

    SMITH, ROBERT G., JR.

    THE NEED FOR A QUALITY CONTROL SYSTEM IN A MILITARY TRAINING PROGRAM AND THE METHODS OF ESTABLISHING SUCH A UNIT ARE DESCRIBED AND EVALUATED IN THIS REPORT. THE PURPOSE OF QUALITY CONTROL IS TO INSURE A SATISFACTORY STANDARD OF COMPETENCE AMONG THE STUDENTS WHO GRADUATE, TO MAINTAIN THIS QUALITY BY A CONTINUOUS MONITORING PROCESS, AND TO IMPROVE…

  11. Iowa Central Quality Fuel Testing Laboratory

    SciTech Connect

    Heach, Don; Bidieman, Julaine

    2013-09-30

    The objective of this project is to finalize the creation of an independent quality fuel testing laboratory on the campus of Iowa Central Community College in Fort Dodge, Iowa that shall provide the exploding biofuels industry a timely and cost-effective centrally located laboratory to complete all state and federal fuel and related tests that are required. The recipient shall work with various state regulatory agencies, biofuel companies and state and national industry associations to ensure that training and testing needs of their members and American consumers are met. The recipient shall work with the Iowa Department of Ag and Land Stewardship on the development of an Iowa Biofuel Quality Standard along with the Development of a standard that can be used throughout industry.

  12. USGS Blind Sample Project: monitoring and evaluating laboratory analytical quality

    USGS Publications Warehouse

    Ludtke, Amy S.; Woodworth, Mark T.

    1997-01-01

    The U.S. Geological Survey (USGS) collects and disseminates information about the Nation's water resources. Surface- and ground-water samples are collected and sent to USGS laboratories for chemical analyses. The laboratories identify and quantify the constituents in the water samples. Random and systematic errors occur during sample handling, chemical analysis, and data processing. Although all errors cannot be eliminated from measurements, the magnitude of their uncertainty can be estimated and tracked over time. Since 1981, the USGS has operated an independent, external, quality-assurance project called the Blind Sample Project (BSP). The purpose of the BSP is to monitor and evaluate the quality of laboratory analytical results through the use of double-blind quality-control (QC) samples. The information provided by the BSP assists the laboratories in detecting and correcting problems in the analytical procedures. The information also can aid laboratory users in estimating the extent that laboratory errors contribute to the overall errors in their environmental data.

  13. Quality Assurance of RNA Expression Profiling in Clinical Laboratories

    PubMed Central

    Tang, Weihua; Hu, Zhiyuan; Muallem, Hind; Gulley, Margaret L.

    2012-01-01

    RNA expression profiles are increasingly used to diagnose and classify disease, based on expression patterns of as many as several thousand RNAs. To ensure quality of expression profiling services in clinical settings, a standard operating procedure incorporates multiple quality indicators and controls, beginning with preanalytic specimen preparation and proceeding thorough analysis, interpretation, and reporting. Before testing, histopathological examination of each cellular specimen, along with optional cell enrichment procedures, ensures adequacy of the input tissue. Other tactics include endogenous controls to evaluate adequacy of RNA and exogenous or spiked controls to evaluate run- and patient-specific performance of the test system, respectively. Unique aspects of quality assurance for array-based tests include controls for the pertinent outcome signatures that often supersede controls for each individual analyte, built-in redundancy for critical analytes or biochemical pathways, and software-supported scrutiny of abundant data by a laboratory physician who interprets the findings in a manner facilitating appropriate medical intervention. Access to high-quality reagents, instruments, and software from commercial sources promotes standardization and adoption in clinical settings, once an assay is vetted in validation studies as being analytically sound and clinically useful. Careful attention to the well-honed principles of laboratory medicine, along with guidance from government and professional groups on strategies to preserve RNA and manage large data sets, promotes clinical-grade assay performance. PMID:22020152

  14. General aviation fuel quality control

    NASA Technical Reports Server (NTRS)

    Poitz, H.

    1983-01-01

    Quality control measures for aviation gasoline, and some of the differences between quality control on avgas and mogas are discussed. One thing to keep in mind is that with motor gasoline you can always pull off to the side of the road. It's not so easy to do in an airplane. Consequently, there are reasons for having the tight specifications and the tight quality control measures on avgas as compared to motor gasoline.

  15. SIMBAD quality-control

    NASA Technical Reports Server (NTRS)

    Lesteven, Soizick

    1992-01-01

    The astronomical database SIMBAD developed at the Centre de donnees astronomiques de Strasbourg presently contains 760,000 objects (stellar and non-stellar). It has the unique characteristic of being structured specifically for astronomical objects. All types of heterogeneous data (bibliographic references, measurements, and sets of identification) are connected with each object. The attributes that define quality of the database include the following. Reliability: cross-identification should not rely upon just exact values object coordinates. It also means that information attached to one simple object should be consistent. The existing data must be controlled in order to start with a reliable base and to cross-identify new data assuring the quality as data grows. Exhaustivity: delays between publication of new informations and their inclusion in the database should be as short as possible. The integrity of the database has to be maintained as data accumulates. Taking the amount of data into consideration and the rate of new data production, it is necessary to use automatic methods. One of the possibilities is to use multivariate data analysis. The factor-space is a n-dimensional relevancy space which is described by the n-axes representing a set of n subject matter headings; the words and phrases can be used to scale the axes and the documents are then a vector average of the terms within them. The application reported herein is based on the NASA-STI bibliographical database. The selected data concern astronomy, astrophysics, and space radiation (102,963 references from 1975 to 1991 included 8070 keywords). The F-space is built from this bibliographical data. By comparing the F-space position obtained from the NASA-STI keywords with the F-space position obtained from the SIMBAD references, the authors will be able to show whether it is possible to retrieve information with a restricted set of words only. If the comparison is valid, this will be a way to enter bibliographic information in the SIMBAD quality control process. Furthermore, it is possible to connect the physical measurements of stars from SIMBAD to literature concerning these stars from the NASA-STI abstracts. The physical properties of stars (e.g. UBV colors) are not randomly distributed. Stars are distributed among different clusters in a physical parameter space. The authors will show that there are some relations between this classification and the literature concerning these objects clusters in a factor space. They will investigate the nature of the relationship between the SIMBAD measurements and the bibliography. These would be new relationships that are not pre-established by an astronomer. In addition, the bibliography could be neutral information that can be used in combination with the measured parameters.

  16. Quality Assurance and Quality Control, Part 2.

    PubMed

    Akers, Michael J

    2015-01-01

    The tragedy surrounding the New England Compounding Center and contaminated steroid syringe preparations clearly points out what can happen if quality-assurance and quality-control procedures are not strictly practiced in the compounding of sterile preparations. This article is part 2 of a two-part article on requirements to comply with United States Pharmacopeia general chapters <797> and <1163> with respect to quality assurance of compounded sterile preparations. Part 1 covered documentation requirements, inspection procedures, compounding accuracy checks, and part of a discussion on bacterial endotoxin testing. Part 2 covers sterility testing, the completion from part 1 on bacterial endotoxin testing, a brief dicussion of United States Pharmacopeia <1163>, and advances in pharmaceutical quality systems. PMID:26714362

  17. Cost Effectiveness of Adopted Quality Requirements in Hospital Laboratories

    PubMed Central

    HAMZA, Alneil; AHMED-ABAKUR, Eltayib; ABUGROUN, Elsir; BAKHIT, Siham; HOLI, Mohamed

    2013-01-01

    Background The present study was designed in quasi-experiment to assess adoption of the essential clauses of particular clinical laboratory quality management requirements based on international organization for standardization (ISO 15189) in hospital laboratories and to evaluate the cost effectiveness of compliance to ISO 15189. Methods: The quality management intervention based on ISO 15189 was conceded through three phases; pre – intervention phase, Intervention phase and Post-intervention phase. Results: In pre-intervention phase the compliance to ISO 15189 was 49% for study group vs. 47% for control group with P value 0.48, while the post intervention results displayed 54% vs. 79% for study group and control group respectively in compliance to ISO 15189 and statistically significant difference (P value 0.00) with effect size (Cohen’s d) of (0.00) in pre-intervention phase and (0.99) in post – intervention phase. The annual average cost per-test for the study group and control group was 1.80 ± 0.25 vs. 1.97 ± 0.39, respectively with P value 0.39 whereas the post-intervention results showed that the annual average total costs per-test for study group and control group was 1.57 ± 0.23 vs 2.08 ± 0.38, P value 0.019 respectively, with cost-effectiveness ratio of (0.88) in pre -intervention phase and (0.52) in post-intervention phase. Conclusion: The planned adoption of quality management requirements (QMS) in clinical laboratories had great effect to increase the compliance percent with quality management system requirement, raise the average total cost effectiveness, and improve the analytical process capability of the testing procedure. PMID:23967422

  18. Evaluation of quality-control data collected by the U.S. Geological Survey for routine water-quality activities at the Idaho National Laboratory, Idaho, 1996–2001

    USGS Publications Warehouse

    Rattray, Gordon W.

    2012-01-01

    The U.S. Geological Survey, in cooperation with the U.S. Department of Energy, collects surface water and groundwater samples at and near the Idaho National Laboratory as part of a routine, site-wide, water-quality monitoring program. Quality-control samples are collected as part of the program to ensure and document the quality of environmental data. From 1996 to 2001, quality-control samples consisting of 204 replicates and 27 blanks were collected at sampling sites. Paired measurements from replicates were used to calculate variability (as reproducibility and reliability) from sample collection and analysis of radiochemical, chemical, and organic constituents. Measurements from field and equipment blanks were used to estimate the potential contamination bias of constituents. The reproducibility of measurements of constituents was calculated from paired measurements as the normalized absolute difference (NAD) or the relative standard deviation (RSD). The NADs and RSDs, as well as paired measurements with censored or estimated concentrations for which NADs and RSDs were not calculated, were compared to specified criteria to determine if the paired measurements had acceptable reproducibility. If the percentage of paired measurements with acceptable reproducibility for a constituent was greater than or equal to 90 percent, then the reproducibility for that constituent was considered acceptable. The percentage of paired measurements with acceptable reproducibility was greater than or equal to 90 percent for all constituents except orthophosphate (89 percent), zinc (80 percent), hexavalent chromium (53 percent), and total organic carbon (TOC; 38 percent). The low reproducibility for orthophosphate and zinc was attributed to calculation of RSDs for replicates with low concentrations of these constituents. The low reproducibility for hexavalent chromium and TOC was attributed to the inability to preserve hexavalent chromium in water samples and high variability with the analytical method for TOC. The reliability of measurements of constituents was estimated from pooled RSDs that were calculated for discrete concentration ranges for each constituent. Pooled RSDs of 15 to 33 percent were calculated for low concentrations of gross-beta radioactivity, strontium-90, ammonia, nitrite, orthophosphate, nickel, selenium, zinc, tetrachloroethene, and toluene. Lower pooled RSDs of 0 to 12 percent were calculated for all other concentration ranges of these constituents, and for all other constituents, except for one concentration range for gross-beta radioactivity, chloride, and nitrate + nitrite; two concentration ranges for hexavalent chromium; and TOC. Pooled RSDs for the 50 to 60 picocuries per liter concentration range of gross-beta radioactivity (reported as cesium-137) and the 10 to 60 milligrams per liter (mg/L) concentration range of nitrate + nitrite (reported as nitrogen [N]) were 17 percent. Chloride had a pooled RSD of 14 percent for the 20 to less than 60 mg/L concentration range. High pooled RSDs of 40 and 51 percent were calculated for two concentration ranges for hexavalent chromium and of 60 percent for TOC. Measurements from (1) field blanks were used to estimate the potential bias associated with environmental samples from sample collection and analysis, (2) equipment blanks were used to estimate the potential bias from cross contamination of samples collected from wells where portable sampling equipment was used, and (3) a source-solution blank was used to verify that the deionized water source-solution was free of the constituents of interest. If more than one measurement was available, the bias was estimated using order statistics and the binomial probability distribution. The source-solution blank had a detectable concentration of hexavalent chromium of 2 micrograms per liter. If this bias was from a source other than the source solution, then about 84 percent of the 117 hexavalent chromium measurements from environmental samples could have a bias of 10 percent or more. Of the 14 field blanks that were collected,

  19. 10 CFR 26.137 - Quality assurance and quality control.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 1 2013-01-01 2013-01-01 false Quality assurance and quality control. 26.137 Section 26.137 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Licensee Testing Facilities § 26.137 Quality assurance and quality control. (a) Quality assurance program. Each licensee testing facility shall have a quality assurance program...

  20. 10 CFR 26.137 - Quality assurance and quality control.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 1 2014-01-01 2014-01-01 false Quality assurance and quality control. 26.137 Section 26.137 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Licensee Testing Facilities § 26.137 Quality assurance and quality control. (a) Quality assurance program. Each licensee testing facility shall have a quality assurance program...

  1. Principles and Practices for Quality Assurance and Quality Control

    USGS Publications Warehouse

    Jones, Berwyn E.

    1999-01-01

    Quality assurance and quality control are vital parts of highway runoff water-quality monitoring projects. To be effective, project quality assurance must address all aspects of the project, including project management responsibilities and resources, data quality objectives, sampling and analysis plans, data-collection protocols, data quality-control plans, data-assessment procedures and requirements, and project outputs. Quality control ensures that the data quality objectives are achieved as planned. The historical development and current state of the art of quality assurance and quality control concepts described in this report can be applied to evaluation of data from prior projects.

  2. Method of analysis at the U.S. Geological Survey California Water Science Center, Sacramento Laboratory - determination of haloacetic acid formation potential, method validation, and quality-control practices

    USGS Publications Warehouse

    Zazzi, Barbara C.; Crepeau, Kathryn L.; Fram, Miranda S.; Bergamaschi, Brian A.

    2005-01-01

    An analytical method for the determination of haloacetic acid formation potential of water samples has been developed by the U.S. Geological Survey California Water Science Center Sacramento Laboratory. The haloacetic acid formation potential is measured by dosing water samples with chlorine under specified conditions of pH, temperature, incubation time, darkness, and residual-free chlorine. The haloacetic acids formed are bromochloroacetic acid, bromodichloroacetic acid, dibromochloroacetic acid, dibromoacetic acid, dichloroacetic acid, monobromoacetic acid, monochloroacetic acid, tribromoacetic acid, and trichloroacetic acid. They are extracted, methylated, and then analyzed using a gas chromatograph equipped with an electron capture detector. Method validation experiments were performed to determine the method accuracy, precision, and detection limit for each of the compounds. Method detection limits for these nine haloacetic acids ranged from 0.11 to 0.45 microgram per liter. Quality-control practices include the use of blanks, quality-control samples, calibration verification standards, surrogate recovery, internal standard, matrix spikes, and duplicates.

  3. Method of Analysis by the U.S. Geological Survey California District Sacramento Laboratory?Determination of Trihalomethane Formation Potential, Method Validation, and Quality-Control Practices

    USGS Publications Warehouse

    Crepeau, Kathryn L.; Fram, Miranda S.; Bush, Noel

    2004-01-01

    An analytical method for the determination of the trihalomethane formation potential of water samples has been developed. The trihalomethane formation potential is measured by dosing samples with chlorine under specified conditions of pH, temperature, incubation time, darkness, and residual-free chlorine, and then analyzing the resulting trihalomethanes by purge and trap/gas chromatography equipped with an electron capture detector. Detailed explanations of the method and quality-control practices are provided. Method validation experiments showed that the trihalomethane formation potential varies as a function of time between sample collection and analysis, residual-free chlorine concentration, method of sample dilution, and the concentration of bromide in the sample.

  4. Implementation of Quality Management in Core Service Laboratories

    PubMed Central

    Creavalle, T.; Dickens, J.; Haque, K.; Raley, C.; Smith, M.W.; Hicks, B.

    2011-01-01

    The Genetics and Genomics group of the Advanced Technology Program of SAIC-Frederick exists to bring innovative genomic expertise, tools and analysis to NCI and the scientific community. The Sequencing Facility (SF) provides next generation short read (Illumina) sequencing capacity to investigators using a streamlined production approach. The Laboratory of Molecular Technology (LMT) offers a wide range of genomics core services including microarray expression analysis, miRNA analysis, long read (Roche) next generation sequencing, transgenic genotyping, Sanger sequencing, and clinical mutation detection services to investigators from across the NIH. SF and LMT are working together to bring online the third generation Pacific Bioscience SMRT sequencing platform. As the technology supporting this genomic research becomes more complex, the need for basic quality processes within all aspects of the core service groups becomes critical. The Quality Management group works alongside members of these labs to establish or improve processes supporting operations control (equipment, reagent and materials management), process improvement (reengineering/optimization, automation, acceptance criteria for new technologies and tech transfer), and quality assurance and customer support (controlled documentation/SOPs, training, service deficiencies and continual improvement efforts). Implementation and expansion of quality programs within unregulated environments demonstrates SAIC Frederick's dedication to providing the highest quality products and services to the NIH community.

  5. Method of Analysis by the U.S. Geological Survey California District Sacramento Laboratory-- Determination of Dissolved Organic Carbon in Water by High Temperature Catalytic Oxidation, Method Validation, and Quality-Control Practices

    USGS Publications Warehouse

    Bird, Susan M.; Fram, Miranda S.; Crepeau, Kathryn L.

    2003-01-01

    An analytical method has been developed for the determination of dissolved organic carbon concentration in water samples. This method includes the results of the tests used to validate the method and the quality-control practices used for dissolved organic carbon analysis. Prior to analysis, water samples are filtered to remove suspended particulate matter. A Shimadzu TOC-5000A Total Organic Carbon Analyzer in the nonpurgeable organic carbon mode is used to analyze the samples by high temperature catalytic oxidation. The analysis usually is completed within 48 hours of sample collection. The laboratory reporting level is 0.22 milligrams per liter.

  6. 40 CFR 51.359 - Quality control.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 2 2010-07-01 2010-07-01 false Quality control. 51.359 Section 51.359....359 Quality control. Quality control measures shall insure that emission testing equipment is... quality control frequencies by using statistical process control to monitor equipment performance on...

  7. 40 CFR 51.359 - Quality control.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 2 2014-07-01 2014-07-01 false Quality control. 51.359 Section 51.359....359 Quality control. Quality control measures shall insure that emission testing equipment is... quality control frequencies by using statistical process control to monitor equipment performance on...

  8. 40 CFR 51.359 - Quality control.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 2 2011-07-01 2011-07-01 false Quality control. 51.359 Section 51.359....359 Quality control. Quality control measures shall insure that emission testing equipment is... quality control frequencies by using statistical process control to monitor equipment performance on...

  9. 40 CFR 51.359 - Quality control.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 2 2013-07-01 2013-07-01 false Quality control. 51.359 Section 51.359....359 Quality control. Quality control measures shall insure that emission testing equipment is... quality control frequencies by using statistical process control to monitor equipment performance on...

  10. 40 CFR 51.359 - Quality control.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 2 2012-07-01 2012-07-01 false Quality control. 51.359 Section 51.359....359 Quality control. Quality control measures shall insure that emission testing equipment is... quality control frequencies by using statistical process control to monitor equipment performance on...

  11. 42 CFR 493.1239 - Standard: General laboratory systems quality assessment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...2011-10-01 false Standard: General laboratory systems quality assessment. 493... STANDARDS AND CERTIFICATION LABORATORY REQUIREMENTS Quality System for Nonwaived Testing General Laboratory Systems § 493.1239...

  12. 42 CFR 493.1239 - Standard: General laboratory systems quality assessment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...2010-10-01 false Standard: General laboratory systems quality assessment. 493... STANDARDS AND CERTIFICATION LABORATORY REQUIREMENTS Quality System for Nonwaived Testing General Laboratory Systems § 493.1239...

  13. 9 QUALITY ASSURANCE AND QUALITY CONTROL 9.1 Introduction

    E-print Network

    9 QUALITY ASSURANCE AND QUALITY CONTROL 9.1 Introduction The goal of quality assurance and quality of the operating license.1 These systems are typically called Quality Assurance Programs. An organization may also that a facility's current Quality Assurance Program can be used. Standard ANSI/ASQC E4-1994 (ASQC 1995) provides

  14. Quality control during IC processing

    NASA Technical Reports Server (NTRS)

    1979-01-01

    Manual gives detailed test procedures for controlling silicon-wafer processing in manufacture of integrated circuits. Included among 43 test procedures are: ionic, bacterial, and solids contamination of high-purity water needed for wafer processing; crystallographic reflection, purity, and orientation; substrate dimensions and finish; thickness of deposited epitaxial films; oxide quality; photoresist characteristics; pinholes in insulating layers; metallized adhesion; and quality of ohmic contact.

  15. Helping You Identify Quality Laboratory Services

    MedlinePLUS

    ... the laboratory. By doing so, you'll have confidence that your tests will be performed properly. Begin ... to choose the laboratory? ? Does the doctor have confidence in the accuracy of the test results? ? Does ...

  16. Laboratory 10 Control Systems Laboratory ECE3557 Laboratory 10

    E-print Network

    feedback controller. · Set the Signal Generator amplitude to 45 pi/180 and frequency to 0.05 Hz. · Set: motor torque · T0: output torque after the gearbox · Jm: motor inertia · Jl: load inertia The parameter define Jeq = JmK2 g + Jl be the equivalent inertia seen by the motor. This implies that To = Jeq l (2

  17. 10 CFR 26.137 - Quality assurance and quality control.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...assurance program. (e) Quality control requirements...entities may not take management actions on the basis...facility's internal quality control program after...discovered in the testing of quality control samples, in...through the processing of management reviews and/or...

  18. 23 CFR 1340.8 - Quality control.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... OBSERVATIONAL SURVEYS OF SEAT BELT USE Survey Design Requirements § 1340.8 Quality control. (a) Quality control... control monitors involved in seat belt use surveys shall have received training in data...

  19. 23 CFR 1340.8 - Quality control.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... OBSERVATIONAL SURVEYS OF SEAT BELT USE Survey Design Requirements § 1340.8 Quality control. (a) Quality control... control monitors involved in seat belt use surveys shall have received training in data...

  20. 23 CFR 1340.8 - Quality control.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... OBSERVATIONAL SURVEYS OF SEAT BELT USE Survey Design Requirements § 1340.8 Quality control. (a) Quality control... control monitors involved in seat belt use surveys shall have received training in data...

  1. SealScope Project Keywords: Seal quality, statistical process control, control chart, quality control, packaging.

    E-print Network

    Davis, Jesse

    SealScope Project Keywords: Seal quality, statistical process control, control chart, quality control, packaging. Settings of the project: For many packaged products, especially in the food industry, the shelf-life is of main interest since the quality of the product is perceived at the moment

  2. Quality control of EUVE databases

    NASA Technical Reports Server (NTRS)

    John, L. M.; Drake, J.

    1992-01-01

    The publicly accessible databases for the Extreme Ultraviolet Explorer include: the EUVE Archive mailserver; the CEA ftp site; the EUVE Guest Observer Mailserver; and the Astronomical Data System node. The EUVE Performance Assurance team is responsible for verifying that these public EUVE databases are working properly, and that the public availability of EUVE data contained therein does not infringe any data rights which may have been assigned. In this poster, we describe the Quality Assurance (QA) procedures we have developed from the approach of QA as a service organization, thus reflecting the overall EUVE philosophy of Quality Assurance integrated into normal operating procedures, rather than imposed as an external, post facto, control mechanism.

  3. 7 CFR 930.44 - Quality control.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Quality control. 930.44 Section 930.44 Agriculture... MICHIGAN, NEW YORK, PENNSYLVANIA, OREGON, UTAH, WASHINGTON, AND WISCONSIN Order Regulating Handling Quality Control § 930.44 Quality control. (a) Quality standards. The Board may establish, with the approval of...

  4. 7 CFR 930.44 - Quality control.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 8 2012-01-01 2012-01-01 false Quality control. 930.44 Section 930.44 Agriculture... MICHIGAN, NEW YORK, PENNSYLVANIA, OREGON, UTAH, WASHINGTON, AND WISCONSIN Order Regulating Handling Quality Control § 930.44 Quality control. (a) Quality standards. The Board may establish, with the approval of...

  5. Quality control in databanks for molecular biology

    E-print Network

    Sussman, Joel L.

    Quality control in databanks for molecular biology CODATA Task Group on Biological Macromolecules surveyed quality control procedures of archival databanks in molecular biology. Our role is `to advise. Quality control procedures provide the second level of protection. Indices of quality, even if they do

  6. 7 CFR 930.44 - Quality control.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Quality control. 930.44 Section 930.44 Agriculture... MICHIGAN, NEW YORK, PENNSYLVANIA, OREGON, UTAH, WASHINGTON, AND WISCONSIN Order Regulating Handling Quality Control § 930.44 Quality control. (a) Quality standards. The Board may establish, with the approval of...

  7. 7 CFR 930.44 - Quality control.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 8 2014-01-01 2014-01-01 false Quality control. 930.44 Section 930.44 Agriculture... MICHIGAN, NEW YORK, PENNSYLVANIA, OREGON, UTAH, WASHINGTON, AND WISCONSIN Order Regulating Handling Quality Control § 930.44 Quality control. (a) Quality standards. The Board may establish, with the approval of...

  8. 40 CFR 136.7 - Quality assurance and quality control.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... referred to as a spiked blank, or laboratory control sample (LCS); (v) Matrix spike (MS) and matrix spike duplicate (MSD), or laboratory fortified matrix (LFM) and LFM duplicate, may be used for suspected...

  9. 40 CFR 136.7 - Quality assurance and quality control.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... referred to as a spiked blank, or laboratory control sample (LCS); (v) Matrix spike (MS) and matrix spike duplicate (MSD), or laboratory fortified matrix (LFM) and LFM duplicate, may be used for suspected...

  10. 40 CFR 136.7 - Quality assurance and quality control.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... referred to as a spiked blank, or laboratory control sample (LCS); (v) Matrix spike (MS) and matrix spike duplicate (MSD), or laboratory fortified matrix (LFM) and LFM duplicate, may be used for suspected...

  11. Quality Assurance/Quality Control Jobs

    NASA Astrophysics Data System (ADS)

    Fanslau, Melody; Young, Janelle

    The production of a quality and safe food product is essential to the success of any food manufacturing facility. Because of this great importance, a career in quality can be extremely rewarding. Without happy customers willing to buy a product, a company would not be able to survive. Quality issues such as foreign objects, spoiled or mislabeled product, failure to meet net weight requirements, or a recall can all turn customers away from buying a product. The food industry is a customer-driven market in which some consumers are brand loyal based on a history of high quality or in which a single bad experience with a product will turn them away for a lifetime. With this said, the main role of a quality department is to help ensure that quality issues such as these are eliminated or kept to a minimum to maintain or increase the number of customers purchasing their product.

  12. [Quality control during radiation therapy].

    PubMed

    Dubray, B; Barillot, I; Anah, J; Missohou, F; Varmenot, N; Batin, E

    2003-08-01

    The aim of quality control procedures during radiation therapy is to check the consistency between actual and prescribed treatments. Given the technical complexity of modern radiotherapy, stricter policies are necessary to meet increasing requirements for quality and safety. Among the various tools available, electronic imaging systems play an increasing role in patient-beam position checking and in vivo dose measurements. Written procedures will have to be established in order to describe the control modalities and frequency, as well as the rules for error corrections according to the treatment intent. Non medical staff will be devoted to new tasks, under the radiation oncologist's responsibility. A special attention should be directed at electronic archives, since the present technology is unlikely to meet the legal requirement to keep medical records accessible for at least 30 years. PMID:12914860

  13. Carcinogen Control in the Chemical Laboratory.

    ERIC Educational Resources Information Center

    Johnson, James S.

    1981-01-01

    Presents general and specific guidelines for handling carcinogens. Additional topics include: definition of potential occupational carcinogens; classification of carcinogens; inventory requirements; signs and labels for materials and laboratories; decontamination and disposal procedures; medical surveillance for employees working with controlled

  14. 21 CFR 606.140 - Laboratory controls.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...MANUFACTURING PRACTICE FOR BLOOD AND BLOOD COMPONENTS Laboratory Controls...and test procedures to assure that blood and blood components are safe, pure, potent...product being tested, or to its donor, or to the specific...

  15. Quality Control of Meteorological Observations

    NASA Technical Reports Server (NTRS)

    Collins, William; Dee, Dick; Rukhovets, Leonid

    1999-01-01

    For the first time, a problem of the meteorological observation quality control (QC) was formulated by L.S. Gandin at the Main Geophysical Observatory in the 70's. Later in 1988 L.S. Gandin began adapting his ideas in complex quality control (CQC) to the operational environment at the National Centers for Environmental Prediction. The CQC was first applied by L.S.Gandin and his colleagues to detection and correction of errors in rawinsonde heights and temperatures using a complex of hydrostatic residuals.Later, a full complex of residuals, vertical and horizontal optimal interpolations and baseline checks were added for the checking and correction of a wide range of meteorological variables. some other of Gandin's ideas were applied and substantially developed at other meteorological centers. A new statistical QC was recently implemented in the Goddard Data Assimilation System. The central component of any quality control is a buddy check which is a test of individual suspect observations against available nearby non-suspect observations. A novel feature of this test is that the error variances which are used for QC decision are re-estimated on-line. As a result, the allowed tolerances for suspect observations can depend on local atmospheric conditions. The system is then better able to accept extreme values observed in deep cyclones, jet streams and so on. The basic statements of this adaptive buddy check are described. Some results of the on-line QC including moisture QC are presented.

  16. Quality Work, Quality Control in Technical Services.

    ERIC Educational Resources Information Center

    Horny, Karen L.

    1985-01-01

    Quality in library technical services is explored in light of changes produced by automation. Highlights include a definition of quality; new opportunities and shifting priorities; cataloging (fullness of records, heading consistency, accountability, local standards, automated checking); need for new skills (management, staff); and boons of…

  17. Approaches to quality management and accreditation in a genetic testing laboratory

    PubMed Central

    Berwouts, Sarah; Morris, Michael A; Dequeker, Elisabeth

    2010-01-01

    Medical laboratories, and specifically genetic testing laboratories, provide vital medical services to different clients: clinicians requesting a test, patients from whom the sample was collected, public health and medical-legal instances, referral laboratories and authoritative bodies. All expect results that are accurate and obtained in an efficient and effective manner, within a suitable time frame and at acceptable cost. There are different ways of achieving the end results, but compliance with International Organization for Standardization (ISO) 15189, the international standard for the accreditation of medical laboratories, is becoming progressively accepted as the optimal approach to assuring quality in medical testing. We present recommendations and strategies designed to aid genetic testing laboratories with the implementation of a quality management system, including key aspects such as document control, external quality assessment, internal quality control, internal audit, management review, validation, as well as managing the human side of change. The focus is on pragmatic approaches to attain the levels of quality management and quality assurance required for accreditation according to ISO 15189, within the context of genetic testing. Attention is also given to implementing efficient and effective quality improvement. PMID:20720559

  18. Research of data quality control based on quality grading

    NASA Astrophysics Data System (ADS)

    Liu, Shuang Hong; Yu, Jian Guo; Yu, Yong Ling

    2011-12-01

    To solve the problem of data quality in data warehouse, the process of data stream in data warehouse and the factors influencing data quality were analyzed; a method for controlling data quality based on quality grading was proposed and the frame of data quality grading system was established. In each process of ETL, the data quality grading system would execute script to calculate values, such as total, component and standard measures in accordance with the definition of Unit Measure, so as to get representation indexes; and then the quality report would be generated according to the indexes and the quality would be graded. The method is applicable to various data warehouse systems.

  19. Research of data quality control based on quality grading

    NASA Astrophysics Data System (ADS)

    Liu, Shuang Hong; Yu, Jian Guo; Yu, Yong Ling

    2012-01-01

    To solve the problem of data quality in data warehouse, the process of data stream in data warehouse and the factors influencing data quality were analyzed; a method for controlling data quality based on quality grading was proposed and the frame of data quality grading system was established. In each process of ETL, the data quality grading system would execute script to calculate values, such as total, component and standard measures in accordance with the definition of Unit Measure, so as to get representation indexes; and then the quality report would be generated according to the indexes and the quality would be graded. The method is applicable to various data warehouse systems.

  20. QUALITY ASSURANCE IN RESEARCH LABORATORIES: RULES AND REASON

    EPA Science Inventory

    Quality Assurance in Research Laboratories: Rules and Reason

    Ron Rogers, Quality Assurance and Records Manager, Environmental Carcinogenesis Division, NHEERL/ORD/US EPA, Research Triangle Park, NC, 27709

    To anyone who has actively participated in research, as I have...

  1. Importance of Quality Control and Quality Assurance of

    E-print Network

    Delene, David J.

    - Merriam-Webster Dictionary. Thesis: Airborne data set that are not quality controlled and quality assured. · Targets within North Dakota. · Obtained 7 seed cases and 6 no seed cases. #12;POLCAST2 Flight Summary

  2. 14 CFR 21.139 - Quality control.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Quality control. 21.139 Section 21.139... PROCEDURES FOR PRODUCTS AND PARTS Production Certificates § 21.139 Quality control. The applicant must show that he has established and can maintain a quality control system for any product, for which...

  3. 14 CFR 21.139 - Quality control.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Quality control. 21.139 Section 21.139... PROCEDURES FOR PRODUCTS AND PARTS Production Certificates § 21.139 Quality control. The applicant must show that he has established and can maintain a quality control system for any product, for which...

  4. Quality-Controlled Motion-Compensated Interpolation

    E-print Network

    Girod, Bernd

    Quality-Controlled Motion-Compensated Interpolation Mina Makar, Derek Pang, Yao-Chung Lin and Bernd the quality of the interpolated frames at the decoder by transmitting a small amount of error control. Our work extends this DSC-based approach to the problem of quality-controlled motion

  5. Quality Control Procedures Applied to Drifter Data

    E-print Network

    Drifter Data Assembly Center Revised December 2003 Quality Control Procedures Applied to Drifter transmitting, and QC data Decodes raw data & applies calibrations Quality controls and interpolates data Makes Jessica Redman #12;Drifter DAC Objective "Our goal is to assemble and provide uniform quality controlled

  6. Quality assurance and quality control in monitoring programs

    USGS Publications Warehouse

    Shampine, W.J.

    1993-01-01

    There are three general characteristics of the data to be collected in a monitoring program that should be met in order to maximize the use and value of the data: the data quality should be known the data type and quality should be consistent and comparable, and the data should be available and accessible. Potential problems with each of these characteristics are addressed effectively by quality assurance and quality control. One of the most important aspects of quality assurance in a monitoring program is the development of a quality assurance plan, which should identify clearly the quality of the data needed and describe in detail the planned actions to provide confidence that the program will meet its stated objectives. Quality control data, which allow for the quality and suitability of the environmental data to be evaluated and ascertained, should be collected and utilized as an integral part of the QA effort associated with a monitoring program.

  7. Quality assurance in drug testing laboratories.

    PubMed

    Smith, M L; Bronner, W E; Shimomura, E T; Levine, B S; Froede, R C

    1990-09-01

    Drug testing is currently regulated for Department of Defense and other federal agency programs and many of the QA actions listed in this article are mandated in the regulations cited. This trend will probably continue in an effort to ensure high-quality test results and may expand into private sector testing. Also, more drugs may be added to the list of the five currently mandated for federal agencies. It remains to be seen if the certified DTLs avoid the pitfalls of past programs. A good QA program will undoubtedly be the key to success. PMID:2253447

  8. Testing a Constrained MPC Controller in a Process Control Laboratory

    ERIC Educational Resources Information Center

    Ricardez-Sandoval, Luis A.; Blankespoor, Wesley; Budman, Hector M.

    2010-01-01

    This paper describes an experiment performed by the fourth year chemical engineering students in the process control laboratory at the University of Waterloo. The objective of this experiment is to test the capabilities of a constrained Model Predictive Controller (MPC) to control the operation of a Double Pipe Heat Exchanger (DPHE) in real time.…

  9. Total Quality Management at an Oak Ridge laboratory and the establishment of an internal quality program

    SciTech Connect

    Dorsey, J.G.

    1993-11-01

    In order for any laboratory to be successful today, it is imperative that a total commitment to quality management be the keystone of that laboratory. Modern industry has begun to recognize that it must reach beyond traditional Quality Assurance methods and enlist the participation of all members of the organization for their unique contributions to make their organizations truly excellent. This report discusses Total Quality Management in the Analytical Services Organization at Oak Ridge, Tennessee. Laboratories are in the Y-12 Plant, which is one of three government sites located in Oak Ridge that are managed by Martin Marietta Energy Systems for the Department of Energy (DOE).

  10. NASA Laboratory Telerobotic Manipulator control system architecture

    NASA Technical Reports Server (NTRS)

    Rowe, J. C.; Butler, P. L.; Glassell, R. L.; Herndon, J. N.

    1992-01-01

    In support of the National Aeronautics and Space Administration (NASA) goals to increase the utilization of dexterous robotic systems in space, the Oak Ridge National Laboratory (ORNL) has developed the Laboratory Telerobotic Manipulator (LTM) system. It is a dexterous, dual-arm, force reflecting teleoperator system with robotic features for NASA ground-based research. This paper describes the overall control system architecture, including both the hardware and software. The control system is a distributed, modular, and hierarchical design with flexible expansion capabilities for future enhancements of both the hardware and software.

  11. NASA Laboratory telerobotic manipulator control system architecture

    NASA Technical Reports Server (NTRS)

    Rowe, J. C.; Butler, P. L.; Glassell, R. L.; Herndon, J. N.

    1991-01-01

    In support of the National Aeronautics and Space Administration (NASA) goals to increase the utilization of dexterous robotic systems in space, the Oak Ridge National Laboratory (ORNL) has developed the Laboratory Telerobotic Manipulator (LTM) system. It is a dexterous, dual-arm, force reflecting teleoperator system with robotic features for NASA ground-based research. This paper describes the overall control system architecture, including both the hardware and software. The control system is a distributed, modular, and hierarchical design with flexible expansion capabilities for future enhancements of both the hardware and software.

  12. Quality Control by Artificial Vision

    SciTech Connect

    Lam, Edmond Y.; Gleason, Shaun Scott; Niel, Kurt S.

    2010-01-01

    Computational technology has fundamentally changed many aspects of our lives. One clear evidence is the development of artificial-vision systems, which have effectively automated many manual tasks ranging from quality inspection to quantitative assessment. In many cases, these machine-vision systems are even preferred over manual ones due to their repeatability and high precision. Such advantages come from significant research efforts in advancing sensor technology, illumination, computational hardware, and image-processing algorithms. Similar to the Special Section on Quality Control by Artificial Vision published two years ago in Volume 17, Issue 3 of the Journal of Electronic Imaging, the present one invited papers relevant to fundamental technology improvements to foster quality control by artificial vision, and fine-tuned the technology for specific applications. We aim to balance both theoretical and applied work pertinent to this special section theme. Consequently, we have seven high-quality papers resulting from the stringent peer-reviewing process in place at the Journal of Electronic Imaging. Some of the papers contain extended treatment of the authors work presented at the SPIE Image Processing: Machine Vision Applications conference and the International Conference on Quality Control by Artificial Vision. On the broad application side, Liu et al. propose an unsupervised texture image segmentation scheme. Using a multilayer data condensation spectral clustering algorithm together with wavelet transform, they demonstrate the effectiveness of their approach on both texture and synthetic aperture radar images. A problem related to image segmentation is image extraction. For this, O'Leary et al. investigate the theory of polynomial moments and show how these moments can be compared to classical filters. They also show how to use the discrete polynomial-basis functions for the extraction of 3-D embossed digits, demonstrating superiority over Fourier-basis functions for this task. Image registration is another important task for machine vision. Bingham and Arrowood investigate the implementation and results in applying Fourier phase matching for projection registration, with a particular focus on nondestructive testing using computed tomography. Readers interested in enriching their arsenal of image-processing algorithms for machine-vision tasks should find these papers enriching. Meanwhile, we have four papers dealing with more specific machine-vision tasks. The first one, Yahiaoui et al., is quantitative in nature, using machine vision for real-time passenger counting. Occulsion is a common problem in counting objects and people, and they circumvent this issue with a dense stereovision system, achieving 97 to 99% accuracy in their tests. On the other hand, the second paper by Oswald-Tranta et al. focuses on thermographic crack detection. An infrared camera is used to detect inhomogeneities, which may indicate surface cracks. They describe the various steps in developing fully automated testing equipment aimed at a high throughput. Another paper describing an inspection system is Molleda et al., which handles flatness inspection of rolled products. They employ optical-laser triangulation and 3-D surface reconstruction for this task, showing how these can be achieved in real time. Last but not least, Presles et al. propose a way to monitor the particle-size distribution of batch crystallization processes. This is achieved through a new in situ imaging probe and image-analysis methods. While it is unlikely any reader may be working on these four specific problems at the same time, we are confident that readers will find these papers inspiring and potentially helpful to their own machine-vision system developments.

  13. Laboratory system strengthening and quality improvement in Ethiopia

    PubMed Central

    Hiwotu, Tilahun M.; Ayana, Gonfa; Mulugeta, Achamyeleh; Kassa, Getachew B.; Kebede, Yenew; Fonjungo, Peter F.; Tibesso, Gudeta; Desale, Adino; Kebede, Adisu; Kassa, Wondwossen; Mekonnen, Tesfaye; Yao, Katy; Luman, Elizabeth T.; Kebede, Amha; Linde, Mary K.

    2015-01-01

    Background In 2010, a National Laboratory Strategic Plan was set forth in Ethiopia to strengthen laboratory quality systems and set the stage for laboratory accreditation. As a result, the Strengthening Laboratory Management Toward Accreditation (SLMTA) programme was initiated in 45 Ethiopian laboratories. Objectives This article discusses the implementation of the programme, the findings from the evaluation process and key challenges. Methods The 45 laboratories were divided into two consecutive cohorts and staff from each laboratory participated in SLMTA training and improvement projects. The average amount of supportive supervision conducted in the laboratories was 68 hours for cohort I and two hours for cohort II. Baseline and exit audits were conducted in 44 of the laboratories and percent compliance was determined using a checklist with scores divided into zero- to five-star rating levels. Results Improvements, ranging from < 1 to 51 percentage points, were noted in 42 laboratories, whilst decreases were recorded in two. The average scores at the baseline and exit audits were 40% and 58% for cohort I (p < 0.01); and 42% and 53% for cohort II (p < 0.01), respectively. The p-value for difference between cohorts was 0.07. At the exit audit, 61% of the first and 48% of the second cohort laboratories achieved an increase in star rating. Poor awareness, lack of harmonisation with other facility activities and the absence of a quality manual were challenges identified. Conclusion Improvements resulting from SLMTA implementation are encouraging. Continuous advocacy at all levels of the health system is needed to ensure involvement of stakeholders and integration with other improvement initiatives and routine activities.

  14. Implementation of Good Clinical Laboratory Practice (GCLP) guidelines within the External Quality Assurance Program Oversight Laboratory (EQAPOL)

    PubMed Central

    Todd, Christopher A.; Sanchez, Ana M.; Garcia, Ambrosia; Denny, Thomas N.; Sarzotti-Kelsoe, Marcella

    2014-01-01

    The EQAPOL contract was awarded to Duke University to develop and manage global proficiency testing programs for flow cytometry-, ELISpot-, and Luminex bead-based assays (cytokine analytes), as well as create a genetically diverse panel of HIV-1 viral cultures to be made available to National Institutes of Health (NIH) researchers. As a part of this contract, EQAPOL was required to operate under Good Clinical Laboratory Practices (GCLP) that are traditionally used for laboratories conducting endpoint assays for human clinical trials. EQAPOL adapted these guidelines to the management of proficiency testing programs while simultaneously incorporating aspects of ISO/IEC 17043 which are specifically designed for external proficiency management. Over the first two years of the contract, the EQAPOL Oversight Laboratories received training, developed standard operating procedures and quality management practices, implemented strict quality control procedures for equipment, reagents, and documentation, and received audits from the EQAPOL Central Quality Assurance Unit. GCLP programs, such as EQAPOL, strengthen a laboratory's ability to perform critical assays and provide quality assessments of future potential vaccines. PMID:24120573

  15. Poorer sleep quality is associated with lower emotion-regulation ability in a laboratory paradigm

    PubMed Central

    Mauss, Iris B.; Troy, Allison S.; LeBourgeois, Monique K.

    2014-01-01

    Theoretical models suggest a positive relationship between sleep quality and individuals' ability to regulate emotion. However, few studies have empirically tested this hypothesized link using standardized laboratory measures of emotion-regulation ability. The present research examined the relationship between sleep quality and the ability to implement a type of emotion regulation that has particularly important implications for psychological health: cognitive reappraisal (cognitively reframing an emotional event so as to dampen its impact). To do so, 156 participants (86 male) reported on their past week's sleep quality. Their ability to implement cognitive reappraisal (CRA) was then measured with a standardized laboratory challenge. Participants with poorer self-reported sleep quality exhibited lower CRA, even after controlling for fourteen potential key confounds (e.g., age, negative affect, mood disorder symptoms, stress). This finding is consistent with the idea that poorer sleep quality may impair individuals' ability to engage in the crucial task of regulating negative emotions. PMID:23025547

  16. DEVELOPMENT OF SUSPENDED SOLIDS QUALITY CONTROL AND PERFORMANCE EVALUATION SAMPLES

    EPA Science Inventory

    A two phase study was conducted to develop a synthetic suspended solids sample for use as quality control check and performance evaluation within environmental monitoring laboratories. The first phase consisted of a feasibility study to determine compounds that exhibited the opti...

  17. 21 CFR 225.58 - Laboratory controls.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Laboratory controls. (a) The periodic assay of medicated feeds for drug components provides a measure of... following assay requirements shall apply to medicated feeds: (1) For feeds requiring a medicated feed mill... specified in this chapter. At least one of these assays shall be performed on the first batch using the...

  18. 21 CFR 225.58 - Laboratory controls.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...Laboratory controls. (a) The periodic assay of medicated feeds for drug components...intended potency. (b) The following assay requirements shall apply to medicated feeds...in this chapter. At least one of these assays shall be performed on the first...

  19. 21 CFR 226.58 - Laboratory controls.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... conditions of shipment, storage, and use. This may consist of a determination on a Type A medicated article(s... 21 Food and Drugs 4 2011-04-01 2011-04-01 false Laboratory controls. 226.58 Section 226.58 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED)...

  20. 21 CFR 226.58 - Laboratory controls.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... conditions of shipment, storage, and use. This may consist of a determination on a Type A medicated article(s... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Laboratory controls. 226.58 Section 226.58 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED)...

  1. A Laboratory Testbed for Embedded Fuzzy Control

    ERIC Educational Resources Information Center

    Srivastava, S.; Sukumar, V.; Bhasin, P. S.; Arun Kumar, D.

    2011-01-01

    This paper presents a novel scheme called "Laboratory Testbed for Embedded Fuzzy Control of a Real Time Nonlinear System." The idea is based upon the fact that project-based learning motivates students to learn actively and to use their engineering skills acquired in their previous years of study. It also fosters initiative and focuses students'…

  2. Mars Science Laboratory thermal control architecture

    NASA Technical Reports Server (NTRS)

    Bhandari, Pradeep; Birur, Gajanana; Pauken, Michael; Paris, Anthony; Novak, Keith; Prina, Mauro; Ramirez, Brenda; Bame, David

    2005-01-01

    The Mars Science Laboratory (MSL) mission to land a large rover on Mars is being planned for launch in 2009. This paper will describe the basic architecture of the thermal control system, the challenges and the methods used to overcome them by the use of an innovative architecture to maximize the use of heritage from past projects while meeting the requirements for the design.

  3. Idaho National Laboratory (INL) Sitewide Institutional Controls Plan

    SciTech Connect

    W. L. Jolley

    2006-07-27

    On November 9, 2002, the U.S. Environmental Protection Agency (EPA), the U.S. Department of Energy (DOE), and the Idaho Department of Environmental Quality approved the Record of Decision Experimental Breeder Reactor-I/Boiling Water Reactor Experiment Area and Miscellaneous Sites, which requires a Sitewide Institutional Controls Plan for the then Idaho National Engineering and Environmental Laboratory (now known as the Idaho National Laboratory). This document, first issued in June 2004, fulfilled that requirement. The revision is needed to provide an update as remedial actions are completed and new areas of concern are found. This Sitewide Institutional Controls Plan is based on guidance in the May 3, 1999, EPA Region 10 Final Policy on the Use of Institutional Controls at Federal Facilities; the September 29, 2000, EPA guidance Institutional Controls: A Site Manager's Guide to Identifying, Evaluating, and Selecting Institutional Controls at Superfund and RCRA Corrective Action Cleanups; and the April 9, 2003, DOE Policy 454.1, "Use of Institutional Controls." These policies establish measures that ensure short- and long-term effectiveness of institutional controls that protect human health and the environment at federal facility sites undergoing remedial action pursuant to the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) and/or corrective action pursuant to the Resource Conservation and Recovery Act (RCRA). The site-specific institutional controls currently in place at the Idaho National Laboratory are documented in this Sitewide Institutional Controls Plan. This plan is being updated, along with the Idaho National Engineering and Environmental Laboratory Comprehensive Facilities and Land Use Plan, to reflect the progress of remedial activities and changes in CERCLA sites.

  4. Information quality-control model

    NASA Technical Reports Server (NTRS)

    Vincent, D. A.

    1971-01-01

    Model serves as graphic tool for estimating complete product objectives from limited input information, and is applied to cost estimations, product-quality evaluations, and effectiveness measurements for manpower resources allocation. Six product quality levels are defined.

  5. Colorado Air Quality Control Regulations and Ambient Air Quality Standards.

    ERIC Educational Resources Information Center

    Colorado State Dept. of Health, Denver. Div. of Air Pollution Control.

    Regulations and standards relative to air quality control in Colorado are defined in this publication. Presented first are definitions of terms, a statement of intent, and general provisions applicable to all emission control regulations adopted by the Colorado Air Pollution Control Commission. Following this, three regulations are enumerated: (1)…

  6. Quality Assurance/Quality Control (QA/QC) Summary for Year 1 of the California Coast Survey Quality Assurance/Quality Control (QA/QC)

    E-print Network

    APPENDIX 1 Quality Assurance/Quality Control (QA/QC) Summary for Year 1 of the California Coast Survey 1 APPENDIX 1 Quality Assurance/Quality Control (QA/QC) Summary for Year 1 of the California Coast Quality Assurance/Quality Control (QA/QC) Summary for Year 1 of the California Coast Survey 2 The data

  7. Evaluation of the International Atomic Energy Agency (IAEA) Safeguards Analytical Laboratory quality assurance program

    NASA Astrophysics Data System (ADS)

    Pietri, C. E.; Bracey, J. T.

    1985-02-01

    Destructive analysis is used to verify the inventory of nuclear materials at nuclear facilities. The reliability and quality of these measurements must be assured in a systematic manner. The development and implementation for the quality assurance measures for the analytical procedures used in the destructive analysis of these safeguards samples are discussed. The procedures used for the destructive analysis of safeguards samples and the statistical evaluation of the resulting measurement data are evaluated. The procedures include analytical methods, quality control measures, and the treatment of data from these activities. Modifications to the system, which would provide routine assurance to management that these procedures are functioning properly to achieve safeguards objectives are recommended. The sample handling procedures, measurement control activities, analytical methods, reference materials, calibration procedures, statistical analysis of data, and data management system are evaluated. The degree to which laboratory quality assurance is achieved is assessed by comparing it to accepted standards of quality assurance.

  8. [Quality control of chemical libraries].

    PubMed

    Galzi, Jean-Luc; Ruggiu, Fiorella; Gizzi, Patrick; Didier, Bruno

    2015-01-01

    The complete sequence of the human genome has been deciphered at the dawn of the new century. This historic event immediately challenged researchers with new needs both in terms of concepts and of working methods. Each scientific community considered how it could tackle these new challenges and it quickly became clear that using small chemical molecules would help discovering and characterizing the function of new proteins. The importance of the genes that the encode new proteins could thus be established in cells, organs and whole organisms. At the initiative of a handful of researchers, French chemists have organized the collection of their molecules and provided them to biologists. By doing so they killed two birds with one stone: on the one hand they created a unique opportunity to add value to their molecules by creating the first academic chemical library, and on the other hand they stimulated the launch of biologically active molecules discovery programs by biologists from the academic sector. It was necessary, however, to raise many compounds and ensure consistent quality control, which quickly became a priority for the chemical libraries to become reliable tools. PMID:26152171

  9. Quality control education in the community college

    NASA Technical Reports Server (NTRS)

    Greene, J. Griffen; Wilson, Steve

    1966-01-01

    This paper describes the Quality Control Program at Daytona Beach Junior College, including course descriptions. The program in quality control required communication between the college and the American Society for Quality Control (ASQC). The college has machinery established for certification of the learning process, and the society has the source of teachers who are competent in the technical field and who are the employers of the educational products. The associate degree for quality control does not have a fixed program, which can serve all needs, any more than all engineering degrees have identical programs. The main ideas which would be common to all quality control programs are the concept of economic control of a repetitive process and the concept of developing individual potentialities into individuals who are needed and productive.

  10. New laboratory tools in the assessment of bone quality.

    PubMed

    Chappard, D; Baslé, M F; Legrand, E; Audran, M

    2011-08-01

    Bone quality is a complex set of intricated and interdependent factors that influence bone strength. A number of methods have emerged to measure bone quality, taking into account the organic or the mineral phase of the bone matrix, in the laboratory. Bone quality is a complex set of different factors that are interdependent. The bone matrix organization can be described at five different levels of anatomical organization: nature (organic and mineral), texture (woven or lamellar), structure (osteons in the cortices and arch-like packets in trabecular bone), microarchitecture, and macroarchitecture. Any change in one of these levels can alter bone quality. An altered bone remodeling can affect bone quality by influencing one or more of these factors. We have reviewed here the main methods that can be used in the laboratory to explore bone quality on bone samples. Bone remodeling can be evaluated by histomorphometry; microarchitecture is explored in 2D on histological sections and in 3D by microCT or synchrotron. Microradiography and scanning electron microscopy in the backscattered electron mode can measure the mineral distribution; Raman and Fourier-transformed infra-red spectroscopy and imaging can simultaneously explore the organic and mineral phase of the matrix on multispectral images; scanning acoustic microscopy and nanoindentation provide biomechanical information on individual trabeculae. Finally, some histological methods (polarization, surface staining, fluorescence, osteocyte staining) may also be of interest in the understanding of quality as a component of bone fragility. A growing number of laboratory techniques are now available. Some of them have been described many years ago and can find a new youth; others having benefited from improvements in physical and computer techniques are now available. PMID:21347743

  11. Tracking and controlling everything that affects quality is the key to a quality management system.

    PubMed

    Hull, Carl; Wray, Bruce; Winslow, Ford; Vilicich, Mark

    2011-11-01

    Every laboratory has a need to track and control the variables that drive the quality of the results. However, each laboratory is unique and what one organization deems to be a critical process to track and control will likely differ from other organizations. Furthermore, there is more than just the end product or result that needs to be tracked and controlled. All of the intermediate products and resources play a significant role in producing the final product and each of these needs to be included in the LIMS. At a high level, this article will present ideas and opinions on the following topics in relation to implementing a LIMS process tracking and control system in a laboratory: The difference between tracking and controlling processes; What to track and control in the lab; The "product" of the laboratory; Preventing mistakes in a laboratory; Comprehensive software platform options; The value of seeing a system as opposed to imagining it; The use of barcodes in the laboratory; and an assessment on using the Risk Based Approach in deciding what to include in the tracking system. PMID:21631414

  12. Quality Control Technician Curriculum. An Elusive Butterfly.

    ERIC Educational Resources Information Center

    Holler, Michael

    Defining and developing a quality control technician curriculum for an associate degree program is a difficult and puzzling job. There are as many definitions of quality control and curriculum ideas as there are educators asked. However, one could start by dividing the field into its major areas--heavy manufacturing, maintenance, research, and…

  13. 30 CFR 28.31 - Quality control plans; contents.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...TRAILING CABLES IN COAL MINES Quality Control § 28.31 Quality control plans; contents. (a) Each quality control plan shall contain provisions for the management of quality, including: (1) Requirements for the production of...

  14. 30 CFR 28.31 - Quality control plans; contents.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...TRAILING CABLES IN COAL MINES Quality Control § 28.31 Quality control plans; contents. (a) Each quality control plan shall contain provisions for the management of quality, including: (1) Requirements for the production of...

  15. Quality Control in Small Groups

    NASA Astrophysics Data System (ADS)

    Lemmens, L. F.

    2008-11-01

    The smallness of some groups in a set up to control the quality of a service using questionnaires limits the size of the samples, this limitation has several consequences. Indeed the common approach used for relatively large groups, based on the central limit theorem and the law of large numbers, cannot be used anymore to construct estimators for the parameters of the model. Using an inverse probability will lift these restrictions. A questionnaire is a collection of items. In an item the respondent indicates on a Likert scale his or her agreement with a statement. Dimensions are a set of items dealing with one aspect of the service. In a questionnaire several dimensions are addressed but usually the items are presented in a random sequence. The model for an item is hierarchical with following components: a multivariate hypergeometric model takes the sampling in a finite population into account, the multinomial serves as a prior for the sampling and the Dirichlet-distribution serves as a prior for the multinomials. The composition of dimensions allows to use the posterior for one of the items as a prior for another item of that dimension and so on. After analysis of several questionnaires using this model, the reliability of the responses from some respondents turned out to be a key-problem, in the sense the responses can be classified into at least two classes and a decision rule had to be developed to neglect some of them. The influence of rejecting some answers, on the confidence for the most plausible statement can be estimated. This leads often to the result that there is only minimal evidence for the most probable statement.

  16. Individualized Quality Control Plan (IQCP): Is It Value-Added for Clinical Microbiology?

    PubMed

    Sharp, Susan E; Miller, Melissa B; Hindler, Janet

    2015-12-01

    The Center for Medicaid and Medicare Services (CMS) recently published their Individualized Quality Control Plan (IQCP [https://www.cms.gov/regulations-and-guidance/legislation/CLIA/Individualized_Quality_Control_Plan_IQCP.html]), which will be the only option for quality control (QC) starting in January 2016 if laboratories choose not to perform Clinical Laboratory Improvement Act (CLIA) [U.S. Statutes at Large 81(1967):533] default QC. Laboratories will no longer be able to use "equivalent QC" (EQC) or the Clinical and Laboratory Standards Institute (CLSI) standards alone for quality control of their microbiology systems. The implementation of IQCP in clinical microbiology laboratories will most certainly be an added burden, the benefits of which are currently unknown. PMID:26447112

  17. Gradient algorithm applied to laboratory quantum control

    SciTech Connect

    Roslund, Jonathan; Rabitz, Herschel

    2009-05-15

    The exploration of a quantum control landscape, which is the physical observable as a function of the control variables, is fundamental for understanding the ability to perform observable optimization in the laboratory. For high control variable dimensions, trajectory-based methods provide a means for performing such systematic explorations by exploiting the measured gradient of the observable with respect to the control variables. This paper presents a practical, robust, easily implemented statistical method for obtaining the gradient on a general quantum control landscape in the presence of noise. In order to demonstrate the method's utility, the experimentally measured gradient is utilized as input in steepest-ascent trajectories on the landscapes of three model quantum control problems: spectrally filtered and integrated second harmonic generation as well as excitation of atomic rubidium. The gradient algorithm achieves efficiency gains of up to approximately three times that of the standard genetic algorithm and, as such, is a promising tool for meeting quantum control optimization goals as well as landscape analyses. The landscape trajectories directed by the gradient should aid in the continued investigation and understanding of controlled quantum phenomena.

  18. Getting started on metrics - Jet Propulsion Laboratory productivity and quality

    NASA Technical Reports Server (NTRS)

    Bush, M. W.

    1990-01-01

    A review is presented to describe the effort and difficulties of reconstructing fifteen years of JPL software history. In 1987 the collection and analysis of project data were started with the objective of creating laboratory-wide measures of quality and productivity for software development. As a result of this two-year Software Product Assurance metrics study, a rough measurement foundation for software productivity and software quality, and an order-of-magnitude quantitative baseline for software systems and subsystems are now available.

  19. [Quality Control in Umbilical Cord Blood Bank

    PubMed

    Zhou, Sheng-Li; Song, Dao-Gang; Shen, Bai-Jun; Pan, Jie

    2001-03-01

    Recent clinical reports have demonstrated that the use of umbilical cord blood (UCB) opened a new source of stem cell for hematopoietic stem cell transplantation, leading to the development of cord blood banks world-wide. Prior to the large scale construction of UCB banks, quality control must be performed for health care providers and manufactures. With increasingly stringent regulatory requirement in blood industry, quality control is playing an important role in the operation of blood centers and stem cell laboratories. Reviewed the lectures in the biology of UCB and UCB banks published in recent years, our experiences were discussed in setting up Shandong blood bank to define process variables associated with the collection of UCB, to determine and optimize the procedures and materials used, to ascertain how UCB can be processed in clean room as mononucleated cell preparations, and to analyze using of long-term storage of UCB in research and clinic in the future. Our conclusions are: (1) the establishment of UCB banks for use in transplantation appears to be easy, effective and particularly suitable approach in China under cGMP conditions; (2) the procedures for volume reduction by closed and semi-automated blood processing system, SSP HLA typing, biocode and local computer net, microbiological tests and the 50 ml cryobags for storage constitute a cost efficient system for large-scale UCB banking; (3) the average of 60 ml UCB collection may contain sufficent marrow repopulating cells for children and most of adult recipients; and (4) hematopoietic stem and progenitor cells in cord blood have a more potent proliferative ability than those derived from bone marrow in cell expansion potentials. PMID:12578654

  20. Controlled Space Physics Experiments using Laboratory Magnetospheres

    NASA Astrophysics Data System (ADS)

    Mauel, M. E.; Kesner, J.; Garnier, D.

    2013-12-01

    Modern society's reliance on space-based platforms for a variety of economic and geopolitical purposes makes understanding the physics of the magnetosphere and "space weather'' one of the most important applications of plasma science. During the past decade, results from the CTX and LDX laboratory magnetospheres and from the RT-1 device at University of Tokyo, we have developed techniques to explore space physics using controlled experiments in laboratory magnetospheres. This presentation briefly reviews observations from the laboratory magnetospheres at Columbia University and MIT, including adiabatic drift-resonant transport, low-frequency MHD turbulence, and the formation of high-beta plasmas with profiles similar to Earth's inner magnetosphere. First principle validation of ``whole plasma'' space weather models have been completed in relevant magnetic geometry, including the spectrum and dynamics of turbulence successfully modeled with nonlinear bounce-averaged gyrokinetic simulations. Plans to explore Alfvénic dynamics and whistler wave trapping are discussed through the achievement of higher-density plasmas using radio-frequency heating. Photographs of the laboratory magnetospheres located at MIT (top) and Columbia University (bottom).

  1. Flying qualities criteria and flight control design

    NASA Technical Reports Server (NTRS)

    Berry, D. T.

    1981-01-01

    Despite the application of sophisticated design methodology, newly introduced aircraft continue to suffer from basic flying qualities deficiencies. Two recent meetings, the DOD/NASA Workshop on Highly Augmented Aircraft Criteria and the NASA Dryden Flight Research Center/Air Force Flight Test Center/AIAA Pilot Induced Oscillation Workshop, addressed this problem. An overview of these meetings is provided from the point of view of the relationship between flying qualities criteria and flight control system design. Among the items discussed are flying qualities criteria development, the role of simulation, and communication between flying qualities specialists and control system designers.

  2. QUALITY CONTROL FOR RESEARCH STUDIES: A CRITICAL PART OF THE QUALITY SYSTEM AT THE U. S. EPA

    EPA Science Inventory

    QUALITY CONTROL FOR RESEARCH STUDIES: A CRITICAL PART OF THE QUALITY SYSTEM AT THE U.S. EPA Mette C.J. Schladweiler, Scientist, and Thomas J. Hughes, QA and Records Manager, Experimental Toxicology Division (ETD), National Health and Environmental Effects Research Laboratory (NHE...

  3. Quality control ranges for testing broth microdilution susceptibility of Flavobacterium columnare and F. psychrophilium to nine antimicrobials

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A multi-laboratory broth microdilution method trial was performed to standardize the specialized test conditions required for fish pathogens Flavobacterium columnare and F. pyschrophilum. Nine laboratories tested the quality control (QC) strains Escherichia coli ATCC 25922 and Aeromonas salmonicid...

  4. [Quality control of printed patient information].

    PubMed

    Herm, Kerstin; Linden, Michael

    2013-05-01

    Printed material is an important part in patient information and is called bibliotherapy. It is subject to quality control similar to any other types of treatment. This paper presents an outline of important quality criteria and methods of quality control. Important quality criteria are: (a) Correctness and validity of content evaluated by mentioning the expertise of the authors, appraisal through external experts, reference to scientific literature, and empirical tests of the content, (b) Readability in respect to text structure measured by the "Flesch-Reading-Ease-Formula" supported by fair graphical design including fond and structure of text, (c) Comprehensibility tested by feedback of patients or standardized by the Hamburg comprehensibility rating, (d) Utility including securing availability, acceptance, differential indication and use. Writing and publication of patient leaflets must be accompanied by quality control measures. PMID:23446824

  5. Novel methodology to assess sputum smear microscopy quality in private laboratories

    PubMed Central

    2012-01-01

    Background In South Asia, it is estimated that 80% of patients choose to attend a private facility for their healthcare needs. Although patients generally believe that the private-sector provides high quality services, private diagnostic laboratories are largely unregulated and little is known about the accuracy of results provided. This study assesses the accuracy of sputum smear microscopy for pulmonary tuberculosis diagnosis in private laboratories operating in Karachi, Pakistan. A novel evaluation methodology was designed in which patient-actors submitted sputum specimens spiked with cultured Mycobacterium tuberculosis (Mtb) for testing such that laboratories were not aware that they were being assessed. Methods Smear-negative sputum specimens from Indus Hospital TB Program patients were collected and combined with an attenuated, cultured Mtb strain to create Mtb-spiked samples; for negative standards, no Mtb was added to the smear-negative sputum specimens. Seven of the largest private laboratories across Karachi were chosen for evaluation and were sent six Mtb-spiked and one Mtb-negative sputum specimens. Patient-actors pretending to be laboratory customers submitted these specimens to each laboratory for testing over a three day period. Results Only three laboratories accurately classified all the Mtb-spiked specimens which were submitted. A further three misclassified all the Mtb-spiked specimens as smear-negative, thus providing the ‘patients’ with false negative results. Conclusions TB sputum smear microscopy services are highly variable across private laboratories and are often of extremely poor quality. Engagement, capacity building and rigorous monitoring of standards at private laboratories are of vital importance for the control of TB. Our findings, while specific for TB diagnostic tests, could be symptomatic of other tests performed in private laboratories and warrant further investigation. PMID:23193964

  6. MATHEMATICAL PROGRAMMING MODELS FOR ENVIRONMENTAL QUALITY CONTROL

    E-print Network

    Greenberg, Harvey J.

    the literature of integrated models that represent pollution in connection with the economy, not specific to air~ngenvironmental quality. The scope includes air, water, and land quality, stemming from the first works in the 1960s States spends more than 2% of its gross domestic product on pollution control, and this is more than any

  7. Striving for Quality Control in Distance Education.

    ERIC Educational Resources Information Center

    Leh, Amy S. C.; Jobin, Andrianna

    2002-01-01

    Discussion of the benefits and drawbacks of distance education and online instruction in higher education focuses on quality control. Topics include quality of product, of learning, and of technology; student prerequisites; instructional design; faculty support systems; and program design, including professional development versus academic degree…

  8. CLAY LINER CONSTRUCTION AND QUALITY CONTROL

    EPA Science Inventory

    Soil handling and liner construction practices at hazardous waste management facilities are documented. Soil characterizations, processing techniques, construction methods, and quality control of constructed liners are reviewed and compared. Results indicate widely different test...

  9. ER quality control can lead to retrograde transport from the ER lumen to the cytosol and the nucleoplasm in plants

    E-print Network

    ER quality control can lead to retrograde transport from the ER lumen to the cytosol-mail fbrandizzi@brookes.ac.uk). y Both laboratories contributed equally. Summary Quality control in the secretory by proteasome inhibitors. Keywords: GFP, ERAD, quality control, secretory pathway. Introduction As nascent

  10. 10 CFR 26.137 - Quality assurance and quality control.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... following performance testing and quality control requirements: (A) The creatinine validity screening test... samples used to challenge a creatinine validity screening test must include at least six samples... test (i.e., creatinine, pH, nitrite and general oxidants, chromium, or halogen) must demonstrate...

  11. 10 CFR 26.137 - Quality assurance and quality control.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... following performance testing and quality control requirements: (A) The creatinine validity screening test... samples used to challenge a creatinine validity screening test must include at least six samples... test (i.e., creatinine, pH, nitrite and general oxidants, chromium, or halogen) must demonstrate...

  12. 10 CFR 26.137 - Quality assurance and quality control.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... following performance testing and quality control requirements: (A) The creatinine validity screening test... samples used to challenge a creatinine validity screening test must include at least six samples... test (i.e., creatinine, pH, nitrite and general oxidants, chromium, or halogen) must demonstrate...

  13. QUALITY ASSURANCE AND QUALITY CONTROL FOR RADIOCHEMICAL ANALYSES AND MEASUREMENTS

    EPA Science Inventory

    Require that each batch of samples analyzed be accompanied by appropriate quality control samples to evaluate accuracy and precision of the results. Require a documented data review and validation process by a minimum of three people before data is released to the client. Requi...

  14. 30 CFR 28.31 - Quality control plans; contents.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.31 Quality control plans; contents. (a) Each quality control plan shall contain provisions for the management of quality, including: (1... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Quality control plans; contents. 28.31...

  15. 30 CFR 28.31 - Quality control plans; contents.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Quality control plans; contents. 28.31 Section... PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.31 Quality control plans; contents. (a) Each quality control plan shall contain provisions for the management of quality, including:...

  16. 30 CFR 28.31 - Quality control plans; contents.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Quality control plans; contents. 28.31 Section... PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.31 Quality control plans; contents. (a) Each quality control plan shall contain provisions for the management of quality, including:...

  17. Network-based production quality control

    NASA Astrophysics Data System (ADS)

    Kwon, Yongjin; Tseng, Bill; Chiou, Richard

    2007-09-01

    This study investigates the feasibility of remote quality control using a host of advanced automation equipment with Internet accessibility. Recent emphasis on product quality and reduction of waste stems from the dynamic, globalized and customer-driven market, which brings opportunities and threats to companies, depending on the response speed and production strategies. The current trends in industry also include a wide spread of distributed manufacturing systems, where design, production, and management facilities are geographically dispersed. This situation mandates not only the accessibility to remotely located production equipment for monitoring and control, but efficient means of responding to changing environment to counter process variations and diverse customer demands. To compete under such an environment, companies are striving to achieve 100%, sensor-based, automated inspection for zero-defect manufacturing. In this study, the Internet-based quality control scheme is referred to as "E-Quality for Manufacturing" or "EQM" for short. By its definition, EQM refers to a holistic approach to design and to embed efficient quality control functions in the context of network integrated manufacturing systems. Such system let designers located far away from the production facility to monitor, control and adjust the quality inspection processes as production design evolves.

  18. Laboratory facility design and microbial indoor air quality in selected hospital laboratories.

    PubMed

    Luksamijarulkul, Pipat; Kiennukul, Nuchanard; Vatthanasomboon, Pisit

    2014-05-01

    Hospital laboratory is one of workplace areas contaminated with a variety of biohazards. A cross sectional study was conducted to assess the microbial air quality and facility design in the laboratories of four selected governmental hospitals (Hospitals A, B, C, and D) in Bangkok, Thailand. One hundred eighty-eight indoor air samples were collected from 40 laboratory rooms to investigate bacterial and fungal counts using the Millipore air tester. Forty air samples were collected from the waiting areas of those laboratories, and 16 outdoor air samples were collected to use for comparison. Additionally, those laboratory facilities were assessed following biosafety facility design (10 items). Results indicated that the facility design of laboratory in the Hospital A met most of items of the biosafety facility criteria. The rest met only seven items of the criteria. Means +/- standard deviation (SD) of bacterial counts of 253.1 +/- 247.7 cfu/m3, 236.8 +/- 200.1 cfu/m3, 304.4 +/- 264.2 cfu/m3, and 146.7 +/- 127.0 cfu/m3, and fungal counts of 500.8 +/- 64.2 cfu/ m3, 425.0 +/- 21.2 cfu/m3, 357.0 +/- 121.2 cfu/m3, and 355.7 +/- 86.8 cfu/m3 were found in hospital laboratories A, B, C and D, respectively. The isolated colonies of bacteria and fungi were identified as group or genus. It was found that the most common bacteria was Staphylococcus spp (84.1%, 76.0%, 72.1% and 80.5%, respectively), whereas, the most common fungi were Aspergillus spp and septate hyphae fungi (42.0%, 37.5%, 39.5%, and 45.7%; vs 38.6%, 56.2%, 52.1%, and 37.2%, respectively). These data may be valuable to develop interventions to improve the microbial indoor air quality among hospital laboratories and for preventing the laboratory-acquired infections. PMID:24974659

  19. Description of the Spacecraft Control Laboratory Experiment (SCOLE) facility

    NASA Technical Reports Server (NTRS)

    Williams, Jeffrey P.; Rallo, Rosemary A.

    1987-01-01

    A laboratory facility for the study of control laws for large flexible spacecraft is described. The facility fulfills the requirements of the Spacecraft Control Laboratory Experiment (SCOLE) design challenge for laboratory experiments, which will allow slew maneuvers and pointing operations. The structural apparatus is described in detail sufficient for modelling purposes. The sensor and actuator types and characteristics are described so that identification and control algorithms may be designed. The control implementation computer and real-time subroutines are also described.

  20. Description of the Spacecraft Control Laboratory Experiment (SCOLE) facility

    NASA Technical Reports Server (NTRS)

    Williams, Jeffrey P.; Rallo, Rosemary A.

    1987-01-01

    A laboratory facility for the study of control laws for large flexible spacecraft is described. The facility fulfills the requirements of the Spacecraft Control Laboratory Experiment (SCOLE) design challenge for a laboratory experiment, which will allow slew maneuvers and pointing operations. The structural apparatus is described in detail sufficient for modelling purposes. The sensor and actuator types and characteristics are described so that identification and control algorithms may be designed. The control implementation computer and real-time subroutines are also described.

  1. Principles of Water Quality Control.

    ERIC Educational Resources Information Center

    Tebbutt, T. H. Y.

    This book is designed as a text for undergraduate civil engineering courses and as preliminary reading for postgraduate courses in public health engineering and water resources technology. It is also intended to be of value to workers already in the field and to students preparing for the examinations of the Institute of Water Pollution Control

  2. The Quality of Sputum Smear Microscopy in Public-Private Mix Directly Observed Treatment Laboratories in West Amhara Region, Ethiopia

    PubMed Central

    Manalebh, Almaw; Demissie, Meaza; Mekonnen, Daniel; Abera, Bayeh

    2015-01-01

    Ethiopia adopted Public-Private Mix Directly Observed Treatment Short Course Chemotherapy (PPM-DOTS) strategy for tuberculosis (TB) control program. Quality of sputum smear microscopy has paramount importance for tuberculosis control program in resource-poor countries like Ethiopia. A cross-sectional study was conducted to assess the quality of sputum smear microscopy in 37 Public-Private Mix laboratories in West Amhara, Ethiopia. The three external quality assessment methods (onsite evaluation, panel testing and blind rechecking) were employed. Onsite assessment revealed that 67.6% of PPM-DOTS laboratories were below the standard physical space (5 X 6) m2. The average monthly workload per laboratory technician was 19.5 (SD±2.9) slides with 12.8% positivity rate. The quality of Acid Fast Bacilli (AFB) staining reagents was sub-standard. The overall agreement for blind rechecking of 1,123 AFB slides was 99.4% (Kappa = 0.97). Reading of 370 AFB panel slides showed 3.5% false reading (Kappa = 0.92). Moreover, the consistency of reading scanty bacilli slides was lower (93%) compared to 1+, 2+ and 3+ bacilli. Based on blind rechecking and panel testing results, PPM-DOTS site laboratories showed good agreement with the reference laboratory. Physical space and qualities of AFB reagents would be areas of intervention to sustain the quality of sputum smear microscopy. Therefore, regular external quality assessment and provision of basic laboratory supplies for TB diagnosis would be the way forward to improve the quality of sputum smear microscopy services in PPM-DOTS laboratories. PMID:25849516

  3. Quality control by a mobile molecular workshop: quality versus quantity.

    PubMed

    Sharma, Ajeet K; Chowdhury, Debashish

    2010-09-01

    Ribosome is a molecular machine that moves on a messenger RNA (mRNA) track while, simultaneously, polymerizing a protein using the mRNA also as the corresponding template. We define, and analytically calculate, two different measures of the efficiency of this machine. However, we argue that its performance is evaluated better in terms of the translational fidelity and the speed with which it polymerizes a protein. We define both these quantities and calculate these analytically. Fidelity is a measure of the quality of the products, while the total quantity of products synthesized in a given interval depends on the speed of polymerization. We show that for synthesizing a large quantity of proteins, it is not necessary to sacrifice the quality. We also explore the effects of the quality control mechanism on the strength of mechanochemical coupling. We suggest experiments for testing some of the ideas presented here. PMID:21230113

  4. Quality control by a mobile molecular workshop: quality versus quantity

    E-print Network

    Ajeet K. Sharma; Debashish Chowdhury

    2010-09-27

    Ribosome is a molecular machine that moves on a mRNA track while, simultaneously, polymerizing a protein using the mRNA also as the corresponding template. We define, and analytically calculate, two different measures of the efficiency of this machine. However, we arugue that its performance is evaluated better in terms of the translational fidelity and the speed with which it polymerizes a protein. We define both these quantities and calculate these analytically. Fidelity is a measure of the quality of the products while the total quantity of products synthesized in a given interval depends on the speed of polymerization. We show that for synthesizing a large quantity of proteins, it is not necessary to sacrifice the quality. We also explore the effects of the quality control mechanism on the strength of mechano-chemical coupling. We suggest experiments for testing some of the ideas presented here.

  5. Evolution of a Low Cost Control Engineering Laboratory.

    ERIC Educational Resources Information Center

    El-Shirbeeny, El-Hosseiny Taha

    1986-01-01

    Presents an approach for building an inexpensive control engineering laboratory to support control courses in an undergraduate engineering program. Outlines the use of simple amplifier circuits and small personal computers in performing control experiments. Proposes an optimum configuration of the laboratory for minimum servicing and adequate…

  6. Safety in the Chemical Laboratory: Fire Safety and Fire Control in the Chemistry Laboratory.

    ERIC Educational Resources Information Center

    Wilbraham, A. C.

    1979-01-01

    Discusses fire safety and fire control in the chemistry laboratory. The combustion process, extinguishing equipment, extinguisher maintenance and location, and fire safety and practices are included. (HM)

  7. HPLC for quality control of polyimides

    NASA Technical Reports Server (NTRS)

    Young, P. R.; Sykes, G. F.

    1979-01-01

    High Pressure Liquid Chromatography (HPLC) as a quality control tool for polyimide resins and prepregs are presented. A data base to help establish accept/reject criteria for these materials was developed. This work is intended to supplement, not replace, standard quality control tests normally conducted on incoming resins and prepregs. To help achieve these objectives, the HPLC separation of LARC-160 polyimide precursor resin was characterized. Room temperature resin aging effects were studied. Graphite reinforced composites made from fresh and aged resin were fabricated and tested to determine if changes observed by HPLC were significant.

  8. 42 CFR 84.40 - Quality control plans; filing requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Quality Control § 84.40 Quality...control plan which shall be designed to assure the quality of respiratory protection provided by the respirator for which approval...

  9. 42 CFR 84.40 - Quality control plans; filing requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Quality Control § 84.40 Quality...control plan which shall be designed to assure the quality of respiratory protection provided by the respirator for which approval...

  10. Review of 18F-FDG Synthesis and Quality Control

    PubMed Central

    Yu, S

    2006-01-01

    This review article covers a concise account on fludeoxyglucose (18F–FDG) synthesis and quality control procedures with emphasis on practical synthesis Currently, 18F–FDG is the most successful PET radiopharmaceutical so far. The advancement in synthesis and quality control of 18F–FDG, together with its approval by the US FDA and the availability of reimbursement, are probably the main reasons for the flourish of clinical PET over the last 20 years. 18F–FDG can be synthesised by either electrophilic fluorination or nucleophilic fluorination reaction. Nucleophilic fluorination using mannose triflate as precursor and Kryptofix or tetrabutylammonium salts (TBA) is widely used because of higher yield and shorter reaction time. The quality control requirements of 18F–FDG can be found in United States Pharmacopeia (USP), British Pharmacopeia (BP), European Pharmacopeia (EP) and the Chemistry, Manufacturing, and Controls (CMC) section from United States Food and Drug Administration (US FDA) PET draft guidance documents. Basic requirements include radionuclidic identity, radiochemical purity, chemical purity, pH, residual solvent, sterility, and bacterial endotoxin level. Some of these tests (sterility, endotoxins and radionuclidic purity) can be finished after the 18F–FDG has been released. Although USP, BP and EP do not require filter membrane integrity test, many laboratories perform this test as an indirect evident of the product sterility. It is also interesting to note that there are major differences in 18F–FDG quality requirements among USP, BP, and CMC. PMID:21614337

  11. Quality Assurance/Quality Control (QA/QC) Summary for the California Rivers and Streams Study

    E-print Network

    APPENDIX 1 Quality Assurance/Quality Control (QA/QC) Summary for the California Rivers and Streams (Bonnema 2011). In general, data quality is demonstrated through analysis of the following quality control may arise so that corrective actions can be implemented. Quality control samples prepared and analyzed

  12. Rotorcraft flying qualities improvement using advanced control

    NASA Technical Reports Server (NTRS)

    Walker, D.; Postlethwaite, I.; Howitt, J.; Foster, N.

    1993-01-01

    We report on recent experience gained when a multivariable helicopter flight control law was tested on the Large Motion Simulator (LMS) at DRA Bedford. This was part of a study into the application of multivariable control theory to the design of full-authority flight control systems for high-performance helicopters. In this paper, we present some of the results that were obtained during the piloted simulation trial and from subsequent off-line simulation and analysis. The performance provided by the control law led to level 1 handling quality ratings for almost all of the mission task elements assessed, both during the real-time and off-line analysis.

  13. 30 CFR 28.30 - Quality control plans; filing requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Quality control plans; filing requirements. 28... PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.30 Quality control plans; filing... part, each applicant shall file with MSHA a proposed quality control plan which shall be designed...

  14. 30 CFR 28.30 - Quality control plans; filing requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Quality control plans; filing requirements. 28... PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.30 Quality control plans; filing... part, each applicant shall file with MSHA a proposed quality control plan which shall be designed...

  15. 30 CFR 28.30 - Quality control plans; filing requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Quality control plans; filing requirements. 28... PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.30 Quality control plans; filing... part, each applicant shall file with MSHA a proposed quality control plan which shall be designed...

  16. 30 CFR 28.30 - Quality control plans; filing requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Quality control plans; filing requirements. 28... PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.30 Quality control plans; filing... part, each applicant shall file with MSHA a proposed quality control plan which shall be designed...

  17. 21 CFR 211.22 - Responsibilities of quality control unit.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 4 2013-04-01 2013-04-01 false Responsibilities of quality control unit. 211.22... Personnel § 211.22 Responsibilities of quality control unit. (a) There shall be a quality control unit that... have been fully investigated. The quality control unit shall be responsible for approving or...

  18. 21 CFR 211.22 - Responsibilities of quality control unit.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 4 2014-04-01 2014-04-01 false Responsibilities of quality control unit. 211.22... Personnel § 211.22 Responsibilities of quality control unit. (a) There shall be a quality control unit that... have been fully investigated. The quality control unit shall be responsible for approving or...

  19. 30 CFR 28.30 - Quality control plans; filing requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Quality control plans; filing requirements. 28... PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.30 Quality control plans; filing... part, each applicant shall file with MSHA a proposed quality control plan which shall be designed...

  20. 42 CFR 84.41 - Quality control plans; contents.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Quality control plans; contents. 84.41 Section 84... AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Quality Control § 84.41 Quality control plans; contents. (a) Each quality control plan shall contain provisions for...

  1. 21 CFR 211.22 - Responsibilities of quality control unit.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 4 2012-04-01 2012-04-01 false Responsibilities of quality control unit. 211.22... Personnel § 211.22 Responsibilities of quality control unit. (a) There shall be a quality control unit that... have been fully investigated. The quality control unit shall be responsible for approving or...

  2. New Directions in Measurement for Software Quality Control

    E-print Network

    Suryn, Witold

    1 New Directions in Measurement for Software Quality Control Paul Krause, Bernd Freimut and Witold Suryn Abstract--Assessing and controlling software quality is still an immature discipline. One is needed to software quality control as compared with manufacturing quality control. In particular

  3. 42 CFR 84.41 - Quality control plans; contents.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Quality control plans; contents. 84.41 Section 84... AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Quality Control § 84.41 Quality control plans; contents. (a) Each quality control plan shall contain provisions for...

  4. 42 CFR 84.40 - Quality control plans; filing requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Quality control plans; filing requirements. 84.40... Control § 84.40 Quality control plans; filing requirements. As a part of each application for approval or... proposed quality control plan which shall be designed to assure the quality of respiratory...

  5. The consistency approach for the quality control of vaccines.

    PubMed

    Hendriksen, Coenraad; Arciniega, Juan L; Bruckner, Lukas; Chevalier, Michel; Coppens, Emmanuelle; Descamps, Johan; Duchêne, Michel; Dusek, David Michael; Halder, Marlies; Kreeftenberg, Hans; Maes, Alexandrine; Redhead, Keith; Ravetkar, Satish D; Spieser, Jean-Marc; Swam, Hanny

    2008-01-01

    Current lot release testing of conventional vaccines emphasizes quality control of the final product and is characterized by its extensive use of laboratory animals. This report, which is based on the outcome of an ECVAM (European Centre for Validation of Alternative Methods, Institute for Health and Consumer Protection, European Commission Joint Research Centre, Ispra, Italy) workshop, discusses the concept of consistency testing as an alternative approach for lot release testing. The consistency approach for the routine release of vaccines is based upon the principle that the quality of vaccines is a consequence of a quality system and of consistent production of lots with similar characteristics to those lots that have been shown to be safe and effective in humans or the target species. The report indicates why and under which circumstances this approach can be applied, the role of the different stakeholders, and the need for international harmonization. It also gives recommendations for its implementation. PMID:17892948

  6. Los Alamos National Laboratory Yucca Mountain Site Characterization Project 1993 Quality Program status report

    SciTech Connect

    Bolivar, S.L.

    1995-05-01

    This status report is for calendar year 1993. It summarizes the annual activities and accomplishments of the Los Alamos National Laboratory (Los Alamos) Yucca Mountain Site Characterization Project (YMP or Project) quality assurance program. By identifying the accomplishments of the quality program, we establish a baseline that will assist in decision making, improve administrative controls and predictability, and allow us to annually identify long term trends and to evaluate improvements. This is the third annual status report (Bolivar, 1992; Bolivar, 1994). This report is divided into two primary sections: Program Activities and Trend Analysis. Under Program Activities, programmatic issues occurring in 1993 are discussed. The goals for 1993 are also listed, followed by a discussion of their status. Lastly, goals for 1994 are identified. The Trend Analysis section is a summary of 1993 quarterly trend reports and provides a good overview of the quality assurance issues of the Los Alamos YMP.

  7. 11. Interior view of control room in Components Test Laboratory ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. Interior view of control room in Components Test Laboratory (T-27), looking north. Photograph shows upgraded instrumentation, piping, and technological modifications installed in 1997-99 to accommodate component testing requirements for the Atlas V missile. - Air Force Plant PJKS, Systems Integration Laboratory, Components Test Laboratory, Waterton Canyon Road & Colorado Highway 121, Lakewood, Jefferson County, CO

  8. 33 CFR 385.21 - Quality control.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... will be produced by a Project Delivery Team. The quality control plan shall be included in the Project Management Plan and shall describe the procedures to be used to ensure compliance with technical and policy requirements during implementation. (b) During development of the Project Management Plan for each project,...

  9. 33 CFR 385.21 - Quality control.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... will be produced by a Project Delivery Team. The quality control plan shall be included in the Project Management Plan and shall describe the procedures to be used to ensure compliance with technical and policy requirements during implementation. (b) During development of the Project Management Plan for each project,...

  10. 33 CFR 385.21 - Quality control.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... will be produced by a Project Delivery Team. The quality control plan shall be included in the Project Management Plan and shall describe the procedures to be used to ensure compliance with technical and policy requirements during implementation. (b) During development of the Project Management Plan for each project,...

  11. 33 CFR 385.21 - Quality control.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... will be produced by a Project Delivery Team. The quality control plan shall be included in the Project Management Plan and shall describe the procedures to be used to ensure compliance with technical and policy requirements during implementation. (b) During development of the Project Management Plan for each project,...

  12. 33 CFR 385.21 - Quality control.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... will be produced by a Project Delivery Team. The quality control plan shall be included in the Project Management Plan and shall describe the procedures to be used to ensure compliance with technical and policy requirements during implementation. (b) During development of the Project Management Plan for each project,...

  13. 30 CFR 74.6 - Quality control.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Quality control. 74.6 Section 74.6 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH COAL MINE DUST SAMPLING DEVICES Approval Requirements for Coal Mine Dust Personal Sampler Unit § 74.6...

  14. 30 CFR 74.6 - Quality control.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Quality control. 74.6 Section 74.6 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH COAL MINE DUST SAMPLING DEVICES Approval Requirements for Coal Mine Dust Personal Sampler Unit § 74.6...

  15. 30 CFR 74.6 - Quality control.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Quality control. 74.6 Section 74.6 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH COAL MINE DUST SAMPLING DEVICES Approval Requirements for Coal Mine Dust Personal Sampler Unit § 74.6...

  16. Quality Control & Design in Science Learning

    ERIC Educational Resources Information Center

    Sumrall, William J.; Schillinger, Don

    2003-01-01

    One area of science education that is, at times, neglected involves lessons on technological concepts of these principles--designing, testing, and quality control. Instead, a focus upon science concepts from a pure, and unapplied, perspective is the norm. Thus, while students may learn the equation "mass divided by volume equals density," the…

  17. 30 CFR 74.6 - Quality control.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Quality control. 74.6 Section 74.6 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH COAL MINE DUST SAMPLING DEVICES Approval Requirements for Coal Mine Dust Personal Sampler Unit § 74.6...

  18. DCEG Hosts Workshop on Microbiome Quality Control

    Cancer.gov

    On September 30 and October 1, DCEG hosted the first workshop to review findings from the MicroBiome Quality Control (MBQC) Project. The MBQC Project is a collaborative effort to comprehensively evaluate appropriate methodologies for this growing field of research, including variability in microbial assessment in sampling handling (including DNA extraction, DNA amplification, and sequencing) and bioinformatics.

  19. 30 CFR 74.6 - Quality control.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Quality control. 74.6 Section 74.6 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH COAL MINE DUST SAMPLING DEVICES Approval Requirements for Coal Mine Dust Personal Sampler Unit § 74.6...

  20. Outsourcing University Degrees: Implications for Quality Control

    ERIC Educational Resources Information Center

    Edwards, Julie; Crosling, Glenda; Edwards, Ron

    2010-01-01

    Education institutions worldwide have and continue to seek opportunities to spread their offerings abroad. While the provision of courses to students located overseas through partner institutions has many advantages, it raises questions about quality control that are not as applicable to other forms of international education. This paper uses a…

  1. Developing risk-based quality control plans: an overview of CLSI EP23-A.

    PubMed

    Person, Nils B

    2013-03-01

    What constitutes quality control (QC) in the clinical laboratory has expanded from being focused on the testing of QC samples to managing the risks of reporting incorrect patient results. To effectively implement this expanded vision of QC, the techniques of risk management are important tools. In 2011, the Clinical and Laboratory Standards Institute published EP23-A, Laboratory Quality Control Based on Risk Management, providing an introduction to risk management techniques and guidance on developing a risk-based QC plan. This article outlines the steps in developing and using a risk based QC plan based on the EP23 model. PMID:23331726

  2. Statistical quality control through overall vibration analysis

    NASA Astrophysics Data System (ADS)

    Carnero, M. a. Carmen; González-Palma, Rafael; Almorza, David; Mayorga, Pedro; López-Escobar, Carlos

    2010-05-01

    The present study introduces the concept of statistical quality control in automotive wheel bearings manufacturing processes. Defects on products under analysis can have a direct influence on passengers' safety and comfort. At present, the use of vibration analysis on machine tools for quality control purposes is not very extensive in manufacturing facilities. Noise and vibration are common quality problems in bearings. These failure modes likely occur under certain operating conditions and do not require high vibration amplitudes but relate to certain vibration frequencies. The vibration frequencies are affected by the type of surface problems (chattering) of ball races that are generated through grinding processes. The purpose of this paper is to identify grinding process variables that affect the quality of bearings by using statistical principles in the field of machine tools. In addition, an evaluation of the quality results of the finished parts under different combinations of process variables is assessed. This paper intends to establish the foundations to predict the quality of the products through the analysis of self-induced vibrations during the contact between the grinding wheel and the parts. To achieve this goal, the overall self-induced vibration readings under different combinations of process variables are analysed using statistical tools. The analysis of data and design of experiments follows a classical approach, considering all potential interactions between variables. The analysis of data is conducted through analysis of variance (ANOVA) for data sets that meet normality and homoscedasticity criteria. This paper utilizes different statistical tools to support the conclusions such as chi squared, Shapiro-Wilks, symmetry, Kurtosis, Cochran, Hartlett, and Hartley and Krushal-Wallis. The analysis presented is the starting point to extend the use of predictive techniques (vibration analysis) for quality control. This paper demonstrates the existence of predictive variables (high-frequency vibration displacements) that are sensible to the processes setup and the quality of the products obtained. Based on the result of this overall vibration analysis, a second paper will analyse self-induced vibration spectrums in order to define limit vibration bands, controllable every cycle or connected to permanent vibration-monitoring systems able to adjust sensible process variables identified by ANOVA, once the vibration readings exceed established quality limits.

  3. External quality assessment of national public health laboratories in Africa, 2002–2009

    PubMed Central

    Perovic, Olga; Fensham, Vivian; McCarthy, Kerrigan; von Gottberg, Anne; de Gouveia, Linda; Poonsamy, Bhavani; Dini, Leigh; Rossouw, Jenny; Keddy, Karen; Alemu, Wondimagegnehu; Yahaya, Ali; Pierson, Antoine; Dolmazon, Virginie; Cognat, Sébastien; Ndihokubwayo, Jean Bosco

    2012-01-01

    Abstract Objective To describe findings from an external quality assessment programme involving laboratories in Africa that routinely investigate epidemic-prone diseases. Methods Beginning in 2002, the Regional Office for Africa of the World Health Organization (WHO) invited national public health laboratories and related facilities in Africa to participate in the programme. Three surveys comprising specimens and questionnaires associated with bacterial enteric diseases, bacterial meningitis, plague, tuberculosis and malaria were sent annually to test participants’ diagnostic proficiency. Identical surveys were sent to referee laboratories for quality control. Materials were prepared, packaged and shipped in accordance with standard protocols. Findings and reports were due within 30 days. Key methodological decisions and test results were categorized as acceptable or unacceptable on the basis of consensus feedback from referees, using established grading schemes. Findings Between 2002 and 2009, participation increased from 30 to 48 Member States of the WHO and from 39 to 78 laboratories. Each survey was returned by 64–93% of participants. Mean turnaround time was 25.9 days. For bacterial enteric diseases and meningitis components, bacterial identification was acceptable in 65% and 69% of challenges, respectively, but serotyping and antibiotic susceptibility testing and reporting were frequently unacceptable. Microscopy was acceptable for 73% of plague challenges. Tuberculosis microscopy was satisfactorily performed, with 87% of responses receiving acceptable scores. In the malaria component, 82% of responses received acceptable scores for species identification but only 51% of parasite quantitation scores were acceptable. Conclusion The external quality assessment programme consistently identified certain functional deficiencies requiring strengthening that were present in African public health microbiology laboratories. PMID:22461714

  4. Quality-Assurance/Quality-Control Manual for Collection and Analysis of Water-Quality Data in the Ohio District, US Geological Survey

    USGS Publications Warehouse

    Francy, D.S.; Jones, A.L.; Myers, D.N.; Rowe, G.L., Jr.; Eberle, Michael; Sarver, K.M.

    1998-01-01

    The U.S. Geological Survey (USGS), Water Resources Division (WRD), requires that quality-assurance/quality-control (QA/QC) activities be included in any sampling and analysis program. Operational QA/QC procedures address local needs while incorporating national policies. Therefore, specific technical policies were established for all activities associated with water-quality project being done by the Ohio District. The policies described in this report provide Ohio District personnel, cooperating agencies, and others with a reference manual on QA/QC procedures that are followed in collecitng and analyzing water-quality samples and reporting water-quality information in the Ohio District. The project chief, project support staff, District Water-Quality Specialist, and District Laboratory Coordinator are all involved in planning and implementing QA/QC activities at the district level. The District Chief and other district-level managers provide oversight, and the Regional Water-Quality Specialist, Office of Water Quality (USGS headquarters), and the Branch of Quality Systems within the Office of Water Quality create national QA/QC polices and provide assistance to District personnel. In the literature, the quality of all measurement data is expressed in terms of precision, variability, bias, accuracy, completeness, representativeness, and comparability. In the Ohio District, bias and variability will be used to describe quality-control data generated from samples in the field and laboratory. Each project chief must plan for implementation and financing of QA/QC activities necessary to achieve data-quality objectives. At least 15 percent of the total project effort must be directed toward QA/QC activities. Of this total, 5-10 percent will be used for collection and analysis of quality-control samples. This is an absolute minimum, and more may be required based on project objectives. Proper techniques must be followed in the collection and processing of surface-water, ground-water, biological, precipitation, bed-sediment, bedload, suspended-sediment, and solid-phase samples. These techniques are briefly described in this report and are extensively documented. The reference documents listed in this report will be kept by the District librarian and District Water-Quality Specialist and updated regularly so that they are available to all District staff. Proper handling and documentation before, during, and after field activities are essential to ensure the integrity of the sample and to correct erroneous reporting of data results. Field sites are to be properly identified and entered into the data base before field data-collection activities begin. During field activities, field notes are to be completed and sample bottles appropriately labeled a nd stored. After field activities, all paperwork is to be completed promptly and samples transferred to the laboratory within allowable holding times. All equipment used by District personnel for the collection and processing of water-quality samples is to be properly operated, maintained, and calibrated by project personnel. This includes equipment for onsite measurement of water-quality characteristics (temperature, specific conductance, pH, dissolved oxygen, alkalinity, acidity, and turbidity) and equipment and instruments used for biological sampling. The District Water-Quality Specialist and District Laboratory Coordinator are responsible for preventive maintenance and calibration of equipment in the Ohio District laboratory. The USGS National Water Quality Laboratory in Arvada, Colo., is the primary source of analytical services for most project work done by the Ohio District. Analyses done at the Ohio District laboratory are usually those that must be completed within a few hours of sample collection. Contract laboratories or other USGS laboratories are sometimes used instead of the NWQL or the Ohio District laboratory. When a contract laboratory is used, the projec

  5. 10. Interior view of control room in Components Test Laboratory ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. Interior view of control room in Components Test Laboratory (T-27), looking east. The control room is located in the center of the building and abuts the Test Cell 8, 9, and 10 and equipment room wings. Photograph shows upgraded instrumentation, piping, and technological modifications installed in 1997-99 to accommodate component testing requirements for the Atlas V missile. - Air Force Plant PJKS, Systems Integration Laboratory, Components Test Laboratory, Waterton Canyon Road & Colorado Highway 121, Lakewood, Jefferson County, CO

  6. Towards Automatic Quantitative Quality Control for MRI.

    PubMed

    Lauzon, Carolyn B; Caffo, Brian C; Landman, Bennett A

    2012-02-23

    Quality and consistency of clinical and research data collected from Magnetic Resonance Imaging (MRI) scanners may become suspect due to a wide variety of common factors including, experimental changes, hardware degradation, hardware replacement, software updates, personnel changes, and observed imaging artifacts. Standard practice limits quality analysis to visual assessment by a researcher/clinician or a quantitative quality control based upon phantoms which may not be timely, cannot account for differing experimental protocol (e.g. gradient timings and strengths), and may not be pertinent to the data or experimental question at hand. This paper presents a parallel processing pipeline developed towards experiment specific automatic quantitative quality control of MRI data using diffusion tensor imaging (DTI) as an experimental test case. The pipeline consists of automatic identification of DTI scans run on the MRI scanner, calculation of DTI contrasts from the data, implementation of modern statistical methods (wild bootstrap and SIMEX) to assess variance and bias in DTI contrasts, and quality assessment via power calculations and normative values. For this pipeline, a DTI specific power calculation analysis is developed as well as the first incorporation of bias estimates in DTI data to improve statistical analysis. PMID:23087586

  7. QUALITY ASSURANCE GUIDELINES FOR LABORATORIES PERFORMING FORENSIC ANALYSIS OF CHEMICAL TERRORISM

    EPA Science Inventory

    The Scientific Working Group on Forensic Analysis of Chemical Terrorism (SWGFACT) has developed the following quality assurance guidelines to provide laboratories engaged in forensic analysis of chemical evidence associated with terrorism a framework to implement a quality assura...

  8. Quality control procedures at Euskalmet data center

    NASA Astrophysics Data System (ADS)

    Hernández, R.; Maruri, M.; Otxoa de Alda, K.; Egaña, J.; Gaztelumendi, S.

    2012-06-01

    The Basque Country Mesonet measures more than 130 000 observations daily from its 85 Automatic Weather Stations (AWS). It becomes clear that automated software is an indispensable tool for quality assurance (QA) of this mesoscale surface observing network. This work describes a set of experimental semi-automatic quality control (QC) routines that is applied at Euskalmet data center. It has paid special attention to level validation design and associated flags, as well as to the system outputs, which are used by meteorologist and maintenance staff.

  9. 7 CFR 58.642 - Quality control tests.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 3 2013-01-01 2013-01-01 false Quality control tests. 58.642 Section 58.642... Procedures § 58.642 Quality control tests. All mix ingredients shall be subject to inspection for quality and condition throughout each processing operation. Quality control tests shall be made on flow line samples...

  10. 7 CFR 58.335 - Quality control tests.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 3 2012-01-01 2012-01-01 false Quality control tests. 58.335 Section 58.335... Procedures § 58.335 Quality control tests. All milk, cream and related products are subject to inspection for quality and condition throughout each processing operation. Quality control tests shall be made on...

  11. 7 CFR 58.335 - Quality control tests.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 3 2013-01-01 2013-01-01 false Quality control tests. 58.335 Section 58.335... Procedures § 58.335 Quality control tests. All milk, cream and related products are subject to inspection for quality and condition throughout each processing operation. Quality control tests shall be made on...

  12. 7 CFR 58.642 - Quality control tests.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 3 2012-01-01 2012-01-01 false Quality control tests. 58.642 Section 58.642... Procedures § 58.642 Quality control tests. All mix ingredients shall be subject to inspection for quality and condition throughout each processing operation. Quality control tests shall be made on flow line samples...

  13. 7 CFR 58.928 - Quality control tests.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 3 2012-01-01 2012-01-01 false Quality control tests. 58.928 Section 58.928... Procedures § 58.928 Quality control tests. All dairy products and other ingredients shall be subject to inspection for quality and condition throughout each processing operation. Quality control tests shall...

  14. 7 CFR 58.335 - Quality control tests.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 3 2014-01-01 2014-01-01 false Quality control tests. 58.335 Section 58.335... Procedures § 58.335 Quality control tests. All milk, cream and related products are subject to inspection for quality and condition throughout each processing operation. Quality control tests shall be made on...

  15. 7 CFR 58.928 - Quality control tests.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 3 2013-01-01 2013-01-01 false Quality control tests. 58.928 Section 58.928... Procedures § 58.928 Quality control tests. All dairy products and other ingredients shall be subject to inspection for quality and condition throughout each processing operation. Quality control tests shall...

  16. 7 CFR 58.928 - Quality control tests.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 3 2014-01-01 2014-01-01 false Quality control tests. 58.928 Section 58.928... Procedures § 58.928 Quality control tests. All dairy products and other ingredients shall be subject to inspection for quality and condition throughout each processing operation. Quality control tests shall...

  17. 7 CFR 58.642 - Quality control tests.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 3 2014-01-01 2014-01-01 false Quality control tests. 58.642 Section 58.642... Procedures § 58.642 Quality control tests. All mix ingredients shall be subject to inspection for quality and condition throughout each processing operation. Quality control tests shall be made on flow line samples...

  18. Quality and Control of Water Vapor Winds

    NASA Technical Reports Server (NTRS)

    Jedlovec, Gary J.; Atkinson, Robert J.

    1996-01-01

    Water vapor imagery from the geostationary satellites such as GOES, Meteosat, and GMS provides synoptic views of dynamical events on a continual basis. Because the imagery represents a non-linear combination of mid- and upper-tropospheric thermodynamic parameters (three-dimensional variations in temperature and humidity), video loops of these image products provide enlightening views of regional flow fields, the movement of tropical and extratropical storm systems, the transfer of moisture between hemispheres and from the tropics to the mid- latitudes, and the dominance of high pressure systems over particular regions of the Earth. Despite the obvious larger scale features, the water vapor imagery contains significant image variability down to the single 8 km GOES pixel. These features can be quantitatively identified and tracked from one time to the next using various image processing techniques. Merrill et al. (1991), Hayden and Schmidt (1992), and Laurent (1993) have documented the operational procedures and capabilities of NOAA and ESOC to produce cloud and water vapor winds. These techniques employ standard correlation and template matching approaches to wind tracking and use qualitative and quantitative procedures to eliminate bad wind vectors from the wind data set. Techniques have also been developed to improve the quality of the operational winds though robust editing procedures (Hayden and Veldon 1991). These quality and control approaches have limitations, are often subjective, and constrain wind variability to be consistent with model derived wind fields. This paper describes research focused on the refinement of objective quality and control parameters for water vapor wind vector data sets. New quality and control measures are developed and employed to provide a more robust wind data set for climate analysis, data assimilation studies, as well as operational weather forecasting. The parameters are applicable to cloud-tracked winds as well with minor modifications. The improvement in winds through use of these new quality and control parameters is measured without the use of rawinsonde or modeled wind field data and compared with other approaches.

  19. Carbon cathode materials: Approval and quality control procedures

    NASA Astrophysics Data System (ADS)

    Øye, Harald A.

    1995-02-01

    A selected group of individuals representing carbon producers, aluminum smelters, a test laboratory, and academia was formed to discuss test methods, approval procedures, and quality control methods of carbon cathode blocks and ramming paste. This paper presents the consensus conclusions reached thus far. Existing standards are commented upon, but the importance of performing tests under operating conditionsis stressed. As described in the following, new ISO standards are proposed in the following areas: sodium expansion, sodium resistance, x-ray characterization, rammability of paste, expansion/shrinkage of paste.

  20. REFERENCE: Gary KT, Duewer DL, Reeder DJ. Graphical tools for RFLP measurement quality assurance: laboratory performance

    E-print Network

    REFERENCE: Gary KT, Duewer DL, Reeder DJ. Graphical tools for RFLP measurement quality assurance and combinations of these "laboratory performance charts" can be used for quality con- trol, quality assurance constructed, this graphical tech- nique can be a useful tool for RFLP quality assurance as well as providing

  1. Application of the Environmental Protection Agency`s data quality objective process to environmental monitoring quality control

    SciTech Connect

    Garcia, L.M.

    1995-11-01

    The United States Environmental Protection Agency`s (EPA) Data Quality Objectives (DQO) process was applied to two environmental monitoring networks for the purpose of optimizing field quality control sampling to give the highest quality monitoring data with minimal impact on resources. The DQO process, developed primarily to aid in cleanup and restoration activities, is a systematic approach to designing sampling, and analysis programs with improved efficiency, cost savings, and measureable and traceable data quality. The two monitoring- networks studied had not been subjected to the systematic review and analysis of the DQO process defined by the EPA. The two monitoring networks studied had relied upon field duplicates or replicates as the main source of field quality control data. Sometimes, both duplicate and routine sample were analyzed by the same analytical laboratory; at other times they were analyzed by different laboratories. This study identified some potential inconsistencies between analytical data and reporting limits from two different laboratories. Application of the EPA DQO process resulted in recommendations for changes in the field quality control sampling program, allowed new insight into the monitoring data, and raised several issues that should be the subject of further investigation.

  2. Field methods and quality-assurance plan for water-quality activities and water-level measurements, U.S. Geological Survey, Idaho National Laboratory, Idaho

    USGS Publications Warehouse

    Bartholomay, Roy C.; Maimer, Neil V.; Wehnke, Amy J.

    2014-01-01

    Water-quality activities and water-level measurements by the personnel of the U.S. Geological Survey (USGS) Idaho National Laboratory (INL) Project Office coincide with the USGS mission of appraising the quantity and quality of the Nation’s water resources. The activities are carried out in cooperation with the U.S. Department of Energy (DOE) Idaho Operations Office. Results of the water-quality and hydraulic head investigations are presented in various USGS publications or in refereed scientific journals and the data are stored in the National Water Information System (NWIS) database. The results of the studies are used by researchers, regulatory and managerial agencies, and interested civic groups. In the broadest sense, quality assurance refers to doing the job right the first time. It includes the functions of planning for products, review and acceptance of the products, and an audit designed to evaluate the system that produces the products. Quality control and quality assurance differ in that quality control ensures that things are done correctly given the “state-of-the-art” technology, and quality assurance ensures that quality control is maintained within specified limits.

  3. Field Methods and Quality-Assurance Plan for Quality-of-Water Activities, U.S. Geological Survey, Idaho National Laboratory, Idaho

    USGS Publications Warehouse

    Knobel, LeRoy L.; Tucker, Betty J.; Rousseau, Joseph P.

    2008-01-01

    Water-quality activities conducted by the staff of the U.S. Geological Survey (USGS) Idaho National Laboratory (INL) Project Office coincide with the USGS mission of appraising the quantity and quality of the Nation's water resources. The activities are conducted in cooperation with the U.S. Department of Energy's (DOE) Idaho Operations Office. Results of the water-quality investigations are presented in various USGS publications or in refereed scientific journals. The results of the studies are highly regarded, and they are used with confidence by researchers, regulatory and managerial agencies, and interested civic groups. In its broadest sense, quality assurance refers to doing the job right the first time. It includes the functions of planning for products, review and acceptance of the products, and an audit designed to evaluate the system that produces the products. Quality control and quality assurance differ in that quality control ensures that things are done correctly given the 'state-of-the-art' technology, and quality assurance ensures that quality control is maintained within specified limits.

  4. Quality assurance practices in Europe: a survey of molecular genetic testing laboratories

    PubMed Central

    Berwouts, Sarah; Fanning, Katrina; Morris, Michael A; Barton, David E; Dequeker, Elisabeth

    2012-01-01

    In the 2000s, a number of initiatives were taken internationally to improve quality in genetic testing services. To contribute to and update the limited literature available related to this topic, we surveyed 910 human molecular genetic testing laboratories, of which 291 (32%) from 29 European countries responded. The majority of laboratories were in the public sector (81%), affiliated with a university hospital (60%). Only a minority of laboratories was accredited (23%), and 26% was certified. A total of 22% of laboratories did not participate in external quality assessment (EQA) and 28% did not use reference materials (RMs). The main motivations given for accreditation were to improve laboratory profile (85%) and national recognition (84%). Nearly all respondents (95%) would prefer working in an accredited laboratory. In accredited laboratories, participation in EQA (P<0.0001), use of RMs (P=0.0014) and availability of continuous education (CE) on medical/scientific subjects (P=0.023), specific tasks (P=0.0018), and quality assurance (P<0.0001) were significantly higher than in non-accredited laboratories. Non-accredited laboratories expect higher restriction of development of new techniques (P=0.023) and improvement of work satisfaction (P=0.0002) than accredited laboratories. By using a quality implementation score (QIS), we showed that accredited laboratories (average score 92) comply better than certified laboratories (average score 69, P<0.001), and certified laboratories better than other laboratories (average score 44, P<0.001), with regard to the implementation of quality indicators. We conclude that quality practices vary widely in European genetic testing laboratories. This leads to a potentially dangerous situation in which the quality of genetic testing is not consistently assured. PMID:22739339

  5. The earth resources technology satellite - Photographic facility quality control program

    NASA Technical Reports Server (NTRS)

    Shaffer, R. M.

    1973-01-01

    A detailed description is given of the quality control program used in the photographic laboratory of the NASA-ERTS Ground Data Handling System. The product response variables measured include tone reproduction, resolution, and low spatial frequency noise. In addition to product response variables, certain performance parameters of the laboratory printers and processors are frequently measured in order to produce consistent duplications of archival photography. A description is given of the operation and use of a densitometer/computer interface which is used to calculate three tone reproduction response variables - film speed, average gradient, and base plus fog density. This procedure eliminates the need for any hand plotting of D log E curves to manually determine response variables.

  6. The Good, the Bad, and the Unknown: Quality of Clinical Laboratories in Kampala, Uganda

    PubMed Central

    Elbireer, Ali M.; Jackson, J. Brooks; Sendagire, Hakim; Opio, Alex; Bagenda, Danstan; Amukele, Timothy K.

    2013-01-01

    Background Clinical laboratories are crucial in addressing the high rates of communicable and non-communicable diseases seen in sub-Saharan Africa (SSA). However, the most basic information, such as the number and quality of clinical laboratories in SSA, is not available. The objective of this study was to create a practical method for obtaining this information in SSA towns and cities using an initial survey in Kampala, Uganda. Methods Kampala city was divided into 5 partially-overlapping regions. Each region was assigned to 2–3 surveyors who identified and surveyed laboratories in their respective regions; in person and on foot. A modified version of the World Health Organization - African Region (WHO/AFRO) Laboratory Strengthening Checklist was used to obtain baseline measures of quality for all clinical laboratories within Kampala city. The surveyors also measured other attributes of each laboratory, such as their affiliation (government, private etc), designation (national hospital, district hospital, standalone etc), staff numbers, and type of staff. Results The survey team identified and surveyed 954 laboratories in Kampala city. 96% of laboratories were private. Only 45 (5%) of the laboratories met or surpassed the lowest quality standards defined by the WHO/AFRO-derived laboratory strengthening tool (1-star). These 45 higher-quality laboratories were, on average, larger and had a higher number of laboratory-specific staff (technologists, phlebotomists etc) than the other 909 laboratories. 688 (72%) of the 954 laboratories were not registered with the Ministry of Health (MoH). Conclusions This comprehensive evaluation of the number, scope, and quality of clinical laboratories in Kampala is the first published survey of its kind in sub-Saharan Africa. The survey findings demonstrated that laboratories in Kampala that had qualified personnel and those that had higher testing volumes, tended to be of higher-quality. PMID:23737993

  7. Philip Morris involvement in the development of an air quality laboratory in El Salvador

    PubMed Central

    Kummerfeldt, C E; Barnoya, J; Bero, L

    2009-01-01

    Background: The tobacco industry has organised research institutions to generate misleading data on indoor air quality, including second-hand smoke exposure and health effects. Objectives: To describe tobacco industry involvement in the organisation and financial support of an air quality research laboratory in El Salvador. Methods: Tobacco industry documents on the internet were systematically searched from August 2007 to February 2008 for air quality studies undertaken in El Salvador, and laboratory personnel were interviewed. Results: Philip Morris sought to establish a network of air quality laboratories throughout Latin America. In El Salvador, in 1997, through Tabacalera de El Salvador (a subsidiary of Philip Morris) and the Salvadoran Foundation for Economic Development (FUSADES), the industry organised an air quality research laboratory. FUSADES was part of the industry’s Latin American Scientific Network, which consisted of doctors hired as consultants who would send air samples from their research to FUSADES. Philip Morris Scientific Affairs personnel hired LabStat, a Canadian-based laboratory, to provide technical assistance to FUSADES (train and assist the laboratory in air quality measurements). In addition, the Washington-based HMS Group successfully implemented a plan to upgrade the laboratory and obtain international certifications. HMS Group also assisted in searching for sustainable funding for FUSADES, including seeking funds from international aid for Hurricane Mitch. Conclusion: Air quality studies that have used the FUSADES laboratory should be carefully interpreted, given the support that this laboratory received from Philip Morris. PMID:19211614

  8. CONTROL ASSAY DEVELOPMENT: METHODOLOGY AND LABORATORY VERIFICATION

    EPA Science Inventory

    The report describes Control Assay Development (CAD), a data acquisition program designed to evaluate the potential applicability of various treatment processes for the control of solid, liquid, and gaseous emissions from coal conversion plants. The CAD program described could be...

  9. Microprocessors: Laboratory Simulation of Industrial Control Applications.

    ERIC Educational Resources Information Center

    Gedeon, David V.

    1981-01-01

    Describes a course to make technical managers more aware of computer technology and how data loggers, programmable controllers, and larger computer systems interact in a hierarchical configuration of manufacturing process control. (SK)

  10. Quantitative Quality Management through Defect Prediction and Statistical Process Control

    E-print Network

    Jalote, Pankaj

    Quantitative Quality Management through Defect Prediction and Statistical Process Control Pankaj of quality management in a software project is to plan suitable quality control activities, and properly, quality management revolves around defects, and delivered defect density, that is, number of defects per

  11. 7 CFR 58.141 - Alternate quality control program.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 3 2012-01-01 2012-01-01 false Alternate quality control program. 58.141 Section 58... Service 1 Quality Specifications for Raw Milk § 58.141 Alternate quality control program. When a plant has in operation an acceptable quality program, at the producer level, which is approved by...

  12. 7 CFR 58.141 - Alternate quality control program.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 3 2013-01-01 2013-01-01 false Alternate quality control program. 58.141 Section 58... Service 1 Quality Specifications for Raw Milk § 58.141 Alternate quality control program. When a plant has in operation an acceptable quality program, at the producer level, which is approved by...

  13. 7 CFR 58.141 - Alternate quality control program.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 3 2014-01-01 2014-01-01 false Alternate quality control program. 58.141 Section 58... Service 1 Quality Specifications for Raw Milk § 58.141 Alternate quality control program. When a plant has in operation an acceptable quality program, at the producer level, which is approved by...

  14. Prediction Models are Basis for Rational Air Quality Control

    ERIC Educational Resources Information Center

    Daniels, Anders; Bach, Wilfrid

    1973-01-01

    An air quality control scheme employing meteorological diffusion, time averaging and frequency, and cost-benefit models is discussed. The methods outlined provide a constant feedback system for air quality control. Flow charts and maps are included. (BL)

  15. Transformer Thermal Modeling: Improving Reliability Using Data Quality Control

    E-print Network

    1 Transformer Thermal Modeling: Improving Reliability Using Data Quality Control Daniel J. Tylavsky as possible. In this work, we use data-quality control and data-set screening to show that model reliability

  16. 30 CFR 28.31 - Quality control plans; contents.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...OF LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS FUSES FOR USE WITH DIRECT CURRENT IN PROVIDING SHORT-CIRCUIT PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.31 Quality control plans;...

  17. 30 CFR 28.31 - Quality control plans; contents.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...OF LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS FUSES FOR USE WITH DIRECT CURRENT IN PROVIDING SHORT-CIRCUIT PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.31 Quality control plans;...

  18. 30 CFR 28.31 - Quality control plans; contents.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...OF LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS FUSES FOR USE WITH DIRECT CURRENT IN PROVIDING SHORT-CIRCUIT PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.31 Quality control plans;...

  19. Manual control of the Langley Laboratory telerobotic manipulator

    NASA Technical Reports Server (NTRS)

    Hankins, Walter W., III; Mixon, Randolph W.

    1989-01-01

    Langley's new Laboratory Teleoperator Manipulator (LTM) provides manual control of seven-degree-of-freedom, replica, force-reflecting, master/slave manipulator arms in two arms simultaneously. This paper describes the LTM, its installation, and plans for a comparable evaluation study of various control input devices to the system. The comparison includes control using the system's master arms, six-degree-of-freedom hand controllers, minimasters, and a force-reflecting hand controller.

  20. College-Controlled Laboratory Schools in the United States--1964.

    ERIC Educational Resources Information Center

    Kelley, Evan H., Comp.

    Part of a doctoral dissertation (SP 001 650), this directory lists 212 institutions with laboratory schools ("a school which is under the administrative control of a collegiate level institution and/or receives the major share of its financial support from such a parent institution") plus 13 institutions which reported the existence of laboratory

  1. Argonne National Laboratory Internal Appraisal Program environment, safety, health/quality assurance oversight

    SciTech Connect

    Winner, G.L.; Siegfried, Y.S.; Forst, S.P.; Meshenberg, M.J.

    1995-06-01

    Argonne National Laboratory`s Internal Appraisal Program has developed a quality assurance team member training program. This program has been developed to provide training to non-quality assurance professionals. Upon successful completion of this training and approval of the Internal Appraisal Program Manager, these personnel are considered qualified to assist in the conduct of quality assurance assessments. The training program has been incorporated into a self-paced, computerized, training session.

  2. Distributed Sensor Architecture for Intelligent Control that Supports Quality of Control and Quality of Service

    PubMed Central

    Poza-Lujan, Jose-Luis; Posadas-Yagüe, Juan-Luis; Simó-Ten, José-Enrique; Simarro, Raúl; Benet, Ginés

    2015-01-01

    This paper is part of a study of intelligent architectures for distributed control and communications systems. The study focuses on optimizing control systems by evaluating the performance of middleware through quality of service (QoS) parameters and the optimization of control using Quality of Control (QoC) parameters. The main aim of this work is to study, design, develop, and evaluate a distributed control architecture based on the Data-Distribution Service for Real-Time Systems (DDS) communication standard as proposed by the Object Management Group (OMG). As a result of the study, an architecture called Frame-Sensor-Adapter to Control (FSACtrl) has been developed. FSACtrl provides a model to implement an intelligent distributed Event-Based Control (EBC) system with support to measure QoS and QoC parameters. The novelty consists of using, simultaneously, the measured QoS and QoC parameters to make decisions about the control action with a new method called Event Based Quality Integral Cycle. To validate the architecture, the first five Braitenberg vehicles have been implemented using the FSACtrl architecture. The experimental outcomes, demonstrate the convenience of using jointly QoS and QoC parameters in distributed control systems. PMID:25723145

  3. Materials Process Design and Control Laboratory Cornell University

    E-print Network

    Zabaras, Nicholas J.

    parameters of two- phase nickel-based superalloy microstructures Uncertainty quantification of multiscale;Materials Process Design and Control Laboratory Cornell University Primary Development Employ model samples. Develop physics-based deterministic solvers to estimate mechanical properties

  4. Quality control in the year 2000.

    PubMed

    Schade, B

    1992-01-01

    'Just-in-time' production is a prerequisite for a company to meet the challenges of competition. Manufacturing cycles have been so successfully optimized that release time now has become a significant factor. A vision for a major quality-control (QC) contribution to profitability in this decade seems to be the just-in-time release. Benefits will go beyond cost savings for lower inventory. The earlier detection of problems will reduce rejections and scrap. In addition, problem analysis and problem-solving will be easier. To achieve just-in-time release, advanced automated systems like robots will become the workhorses in QC for high volume pharmaceutical production. The requirements for these systems are extremely high in terms of quality, reliability and ruggedness. Crucial for the success might be advances in use of microelectronics for error checks, system recording, trouble shooting, etc. as well as creative new approaches (for example the use of redundant assay systems). PMID:18924930

  5. 7 CFR 275.21 - Quality control review reports.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 4 2011-01-01 2011-01-01 false Quality control review reports. 275.21 Section 275.21... Reporting on Program Performance § 275.21 Quality control review reports. (a) General. Each State agency shall submit reports on the performance of quality control reviews in accordance with the...

  6. 42 CFR 84.40 - Quality control plans; filing requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Quality control plans; filing requirements. 84.40... SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Quality Control § 84.40 Quality control plans; filing requirements. As a part of each application for approval...

  7. 42 CFR 84.40 - Quality control plans; filing requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Quality control plans; filing requirements. 84.40... SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Quality Control § 84.40 Quality control plans; filing requirements. As a part of each application for approval...

  8. 7 CFR 275.21 - Quality control review reports.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 4 2014-01-01 2014-01-01 false Quality control review reports. 275.21 Section 275.21... Reporting on Program Performance § 275.21 Quality control review reports. (a) General. Each State agency shall submit reports on the performance of quality control reviews in accordance with the...

  9. 46 CFR 164.019-13 - Production quality control requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Production quality control requirements. 164.019-13....019-13 Production quality control requirements. (a) General. Each component manufacturer shall establish procedures for maintaining quality control of the materials used in production,...

  10. 18 CFR 12.40 - Quality control programs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... contractor, quality control inspection must be performed by the licensee, the design engineer, or an... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Quality control... PROJECT WORKS Other Responsibilities of Applicant or Licensee § 12.40 Quality control programs....

  11. 18 CFR 12.40 - Quality control programs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... contractor, quality control inspection must be performed by the licensee, the design engineer, or an... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Quality control... PROJECT WORKS Other Responsibilities of Applicant or Licensee § 12.40 Quality control programs....

  12. 46 CFR 164.019-13 - Production quality control requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 6 2011-10-01 2011-10-01 false Production quality control requirements. 164.019-13....019-13 Production quality control requirements. (a) General. Each component manufacturer shall establish procedures for maintaining quality control of the materials used in production,...

  13. 18 CFR 12.40 - Quality control programs.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... contractor, quality control inspection must be performed by the licensee, the design engineer, or an... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Quality control... PROJECT WORKS Other Responsibilities of Applicant or Licensee § 12.40 Quality control programs....

  14. 42 CFR 84.40 - Quality control plans; filing requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Quality control plans; filing requirements. 84.40... SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Quality Control § 84.40 Quality control plans; filing requirements. As a part of each application for approval...

  15. 7 CFR 275.21 - Quality control review reports.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Quality control review reports. 275.21 Section 275.21... Reporting on Program Performance § 275.21 Quality control review reports. (a) General. Each State agency shall submit reports on the performance of quality control reviews in accordance with the...

  16. 46 CFR 164.019-13 - Production quality control requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 6 2014-10-01 2014-10-01 false Production quality control requirements. 164.019-13....019-13 Production quality control requirements. (a) General. Each component manufacturer shall establish procedures for maintaining quality control of the materials used in production,...

  17. 14 CFR 145.211 - Quality control system.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Quality control system. 145.211 Section 145...) SCHOOLS AND OTHER CERTIFICATED AGENCIES REPAIR STATIONS Operating Rules § 145.211 Quality control system. (a) A certificated repair station must establish and maintain a quality control system acceptable...

  18. Quality Control in Crowdsourcing Systems Mohammad Allahbakhsh1

    E-print Network

    New South Wales, University of

    Quality Control in Crowdsourcing Systems Mohammad Allahbakhsh1 Boualem Benatallah1 Hamid Reza. Quality control is a critical aspect in crowdsourcing. This article proposes a framework for characterizing various dimensions of the quality control in crowdsourcing sys- tems. We also review some existing

  19. 21 CFR 640.56 - Quality control test for potency.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 7 2013-04-01 2013-04-01 false Quality control test for potency. 640.56 Section...) BIOLOGICS ADDITIONAL STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS Cryoprecipitate § 640.56 Quality control test for potency. (a) Quality control tests for potency of antihemophilic factor shall be...

  20. 7 CFR 275.21 - Quality control review reports.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 4 2013-01-01 2013-01-01 false Quality control review reports. 275.21 Section 275.21... Reporting on Program Performance § 275.21 Quality control review reports. (a) General. Each State agency shall submit reports on the performance of quality control reviews in accordance with the...

  1. 21 CFR 640.56 - Quality control test for potency.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 7 2012-04-01 2012-04-01 false Quality control test for potency. 640.56 Section...) BIOLOGICS ADDITIONAL STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS Cryoprecipitate § 640.56 Quality control test for potency. (a) Quality control tests for potency of antihemophilic factor shall be...

  2. 14 CFR 145.211 - Quality control system.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Quality control system. 145.211 Section 145...) SCHOOLS AND OTHER CERTIFICATED AGENCIES REPAIR STATIONS Operating Rules § 145.211 Quality control system. (a) A certificated repair station must establish and maintain a quality control system acceptable...

  3. 42 CFR 84.41 - Quality control plans; contents.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Quality control plans; contents. 84.41 Section 84.41 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Quality Control § 84.41 Quality control plans; contents. (a)...

  4. 42 CFR 84.40 - Quality control plans; filing requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Quality control plans; filing requirements. 84.40 Section 84.40 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Quality Control § 84.40 Quality control plans;...

  5. 14 CFR 145.211 - Quality control system.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Quality control system. 145.211 Section 145...) SCHOOLS AND OTHER CERTIFICATED AGENCIES REPAIR STATIONS Operating Rules § 145.211 Quality control system. (a) A certificated repair station must establish and maintain a quality control system acceptable...

  6. STATISTICAL APPROACH TO VOICE QUALITY CONTROL IN ESOPHAGEAL SPEECH ENHANCEMENT

    E-print Network

    Duh, Kevin

    STATISTICAL APPROACH TO VOICE QUALITY CONTROL IN ESOPHAGEAL SPEECH ENHANCEMENT Kenzo Yamamoto This paper describes a voice quality control method in statistical esophageal speech enhancement. Esophageal-to-Speech using regression techniques to make it possible to manually control the converted voice quality

  7. 18 CFR 12.40 - Quality control programs.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Quality control... PROJECT WORKS Other Responsibilities of Applicant or Licensee § 12.40 Quality control programs. (a... meeting any requirements or standards set by the Regional Engineer. If a quality control program...

  8. QUALITY PREDICTION AND CONTROL IN ROLLING PROCESSES USING LOGISTIC REGRESSION

    E-print Network

    Li, Jing

    QUALITY PREDICTION AND CONTROL IN ROLLING PROCESSES USING LOGISTIC REGRESSION Ran Jin, Jing Li KEYWORDS Quality Prediction, Control, Logistic Regression, PCA ABSTRACT With the advancement of distributed predicted. If the predicted quality is worse than a target value, active control is initiated by adjusting

  9. Optimal Resource Allocation for the Quality Control Process Pankaj Jalote

    E-print Network

    Jalote, Pankaj

    Optimal Resource Allocation for the Quality Control Process Pankaj Jalote Department of Computer Sc Abstract Software development project employs some Quality Control (QC) process to detect and remove to their injection, quality control (QC) stages frequently follow the develop- ment stages, in addition to the QC

  10. 46 CFR 164.120-11 - Production quality control requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 6 2012-10-01 2012-10-01 false Production quality control requirements. 164.120-11... Rescue Boats § 164.120-11 Production quality control requirements. The resin manufacturer must institute a quality control procedure to ensure that all Coast Guard-accepted resin is produced to the...

  11. 21 CFR 640.56 - Quality control test for potency.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 7 2014-04-01 2014-04-01 false Quality control test for potency. 640.56 Section...) BIOLOGICS ADDITIONAL STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS Cryoprecipitate § 640.56 Quality control test for potency. (a) Quality control tests for potency of antihemophilic factor shall be...

  12. 46 CFR 164.120-11 - Production quality control requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 6 2013-10-01 2013-10-01 false Production quality control requirements. 164.120-11... Rescue Boats § 164.120-11 Production quality control requirements. The resin manufacturer must institute a quality control procedure to ensure that all Coast Guard-accepted resin is produced to the...

  13. 21 CFR 864.8625 - Hematology quality control mixture.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Hematology quality control mixture. 864.8625 Section 864.8625 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... quality control mixture. (a) Identification. A hematology quality control mixture is a device used...

  14. 21 CFR 864.8625 - Hematology quality control mixture.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Hematology quality control mixture. 864.8625 Section 864.8625 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... quality control mixture. (a) Identification. A hematology quality control mixture is a device used...

  15. 21 CFR 864.8625 - Hematology quality control mixture.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Hematology quality control mixture. 864.8625 Section 864.8625 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... quality control mixture. (a) Identification. A hematology quality control mixture is a device used...

  16. 21 CFR 864.8625 - Hematology quality control mixture.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Hematology quality control mixture. 864.8625 Section 864.8625 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... quality control mixture. (a) Identification. A hematology quality control mixture is a device used...

  17. 21 CFR 864.8625 - Hematology quality control mixture.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Hematology quality control mixture. 864.8625 Section 864.8625 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... quality control mixture. (a) Identification. A hematology quality control mixture is a device used...

  18. CSE4939W CSE Design Laboratory Software Quality Analysis (Initial and Revised)

    E-print Network

    Demurjian, Steven A.

    CSE4939W CSE Design Laboratory Software Quality Analysis (Initial and Revised) From any software/domain. The attainment/incorporation of the quality in your specification and eventually in your design engineering textbook, there are a number of vital software qualities that need to be considered for any given

  19. Antimisting kerosene: Base fuel effects, blending and quality control techniques

    NASA Technical Reports Server (NTRS)

    Yavrouian, A. H.; Ernest, J.; Sarohia, V.

    1984-01-01

    The problems associated with blending of the AMK additive with Jet A, and the base fuel effects on AMK properties are addressed. The results from the evaluation of some of the quality control techniques for AMK are presented. The principal conclusions of this investigation are: significant compositional differences for base fuel (Jet A) within the ASTM specification DI655; higher aromatic content of the base fuel was found to be beneficial for the polymer dissolution at ambient (20 C) temperature; using static mixer technology, the antimisting additive (FM-9) is in-line blended with Jet A, producing AMK which has adequate fire-protection properties 15 to 20 minutes after blending; degradability of freshly blended and equilibrated AMK indicated that maximum degradability is reached after adequate fire protection is obtained; the results of AMK degradability as measured by filter ratio, confirmed previous RAE data that power requirements to decade freshly blended AMK are significantly higher than equilibrated AMK; blending of the additive by using FM-9 concentrate in Jet A produces equilibrated AMK almost instantly; nephelometry offers a simple continuous monitoring capability and is used as a real time quality control device for AMK; and trajectory (jet thurst) and pressure drop tests are useful laboratory techniques for evaluating AMK quality.

  20. Information Quality in Regulatory Decision Making: Peer Review versus Good Laboratory Practice

    PubMed Central

    Borgert, Christopher J.; Mihaich, Ellen M.

    2012-01-01

    Background: There is an ongoing discussion on the provenance of toxicity testing data regarding how best to ensure its validity and credibility. A central argument is whether journal peer-review procedures are superior to Good Laboratory Practice (GLP) standards employed for compliance with regulatory mandates. Objective: We sought to evaluate the rationale for regulatory decision making based on peer-review procedures versus GLP standards. Method: We examined pertinent published literature regarding how scientific data quality and validity are evaluated for peer review, GLP compliance, and development of regulations. Discussion: Some contend that peer review is a coherent, consistent evaluative procedure providing quality control for experimental data generation, analysis, and reporting sufficient to reliably establish relative merit, whereas GLP is seen as merely a tracking process designed to thwart investigator corruption. This view is not supported by published analyses pointing to subjectivity and variability in peer-review processes. Although GLP is not designed to establish relative merit, it is an internationally accepted quality assurance, quality control method for documenting experimental conduct and data. Conclusions: Neither process is completely sufficient for establishing relative scientific soundness. However, changes occurring both in peer-review processes and in regulatory guidance resulting in clearer, more transparent communication of scientific information point to an emerging convergence in ensuring information quality. The solution to determining relative merit lies in developing a well-documented, generally accepted weight-of-evidence scheme to evaluate both peer-reviewed and GLP information used in regulatory decision making where both merit and specific relevance inform the process. PMID:22343028

  1. Quality management in European screening laboratories in blood establishments: A view of current approaches and trends.

    PubMed

    Pereira, Paulo; Westgard, James O; Encarnação, Pedro; Seghatchian, Jerard; de Sousa, Gracinda

    2015-04-01

    The screening laboratory has a critical role in the post-transfusion safety. The success of its targets and efficiency depends on the management system used. Even though the European Union directive 2002/98/EC requires a quality management system in blood establishments, its requirements for screening laboratories are generic. Complementary approaches are needed to implement a quality management system focused on screening laboratories. This article briefly discusses the current good manufacturing practices and good laboratory practices, as well as the trends in quality management system standards. ISO 9001 is widely accepted in some European Union blood establishments as the quality management standard, however this is not synonymous of its successful application. The ISO "risk-based thinking" is interrelated with the quality risk-management process of the EuBIS "Standards and criteria for the inspection of blood establishments". ISO 15189 should be the next step on the quality assurance of a screening laboratory, since it is focused on medical laboratory. To standardize the quality management systems in blood establishments' screening laboratories, new national and European claims focused on technical requirements following ISO 15189 is needed. PMID:25765135

  2. Controlling Laboratory Processes From A Personal Computer

    NASA Technical Reports Server (NTRS)

    Will, H.; Mackin, M. A.

    1991-01-01

    Computer program provides natural-language process control from IBM PC or compatible computer. Sets up process-control system that either runs without operator or run by workers who have limited programming skills. Includes three smaller programs. Two of them, written in FORTRAN 77, record data and control research processes. Third program, written in Pascal, generates FORTRAN subroutines used by other two programs to identify user commands with device-driving routines written by user. Also includes set of input data allowing user to define user commands to be executed by computer. Requires personal computer operating under MS-DOS with suitable hardware interfaces to all controlled devices. Also requires FORTRAN 77 compiler and device drivers written by user.

  3. Development of a Laboratory Cement Quality Analysis Apparatus Based on Laser-Induced Breakdown Spectroscopy

    NASA Astrophysics Data System (ADS)

    Fan, Juanjuan; Zhang, Lei; Wang, Xin; Li, Yufang; Gong, Yao; Dong, Lei; Ma, Weiguang; Yin, Wangbao; Wang, Zhe; Li, Zheng; Zhang, Xiangjie; Li, Yi; Jia, Suotang

    2015-11-01

    Determination of the chemical composition of cement and ratio values of clinker plays an important role in cement plants as part of the optimal process control and product quality evaluation. In the present paper, a laboratory laser-induced breakdown spectroscopy (LIBS) apparatus mainly comprising a sealed optical module and an analysis chamber has been designed for possible application in cement plants for on-site quality analysis of cement. Emphasis is placed on the structure and operation of the LIBS apparatus, the sealed optical path, the temperature controlled spectrometer, the sample holder, the proper calibration model established for minimizing the matrix effects, and a correction method proposed for overcoming the ‘drift’ obstacle. Good agreement has been found between the laboratory measurement results from the LIBS method and those from the traditional method. The absolute measurement errors presented here for oxides analysis are within 0.5%, while those of ratio values are in the range of 0.02 to 0.05. According to the obtained results, this laboratory LIBS apparatus is capable of performing reliable and accurate, composition and proximate analysis of cement and is suitable for application in cement plants. supported by National Natural Science Foundation of China (Nos. 61127017, 61378047, 61205216, 61178009, 61108030, 61475093, and 61275213), the National Key Technology R&D Program of China (No. 2013BAC14B01), the 973 Program of China (No. 2012CB921603), the Shanxi Natural Science Foundation, China (Nos. 2013021004-1, 2012021022-1), and the Shanxi Scholarship Council of China (Nos. 2013-011 and 2013-01)

  4. Protein quality control in the bacterial periplasm

    PubMed Central

    Miot, Marika; Betton, Jean-Michel

    2004-01-01

    The proper functioning of extracytoplasmic proteins requires their export to, and productive folding in, the correct cellular compartment. All proteins in Escherichia coli are initially synthesized in the cytoplasm, then follow a pathway that depends upon their ultimate cellular destination. Many proteins destined for the periplasm are synthesized as precursors carrying an N-terminal signal sequence that directs them to the general secretion machinery at the inner membrane. After translocation and signal sequence cleavage, the newly exported mature proteins are folded and assembled in the periplasm. Maintaining quality control over these processes depends on chaperones, folding catalysts, and proteases. This article summarizes the general principles which control protein folding in the bacterial periplasm by focusing on the periplasmic maltose-binding protein. PMID:15132751

  5. Quality assurance and quality control of geochemical data—A primer for the research scientist

    USGS Publications Warehouse

    Geboy, Nicholas J.; Engle, Mark A.

    2011-01-01

    Geochemistry is a constantly expanding science. More and more, scientists are employing geochemical tools to help answer questions about the Earth and earth system processes. Scientists may assume that the responsibility of examining and assessing the quality of the geochemical data they generate is not theirs but rather that of the analytical laboratories to which their samples have been submitted. This assumption may be partially based on knowledge about internal and external quality assurance and quality control (QA/QC) programs in which analytical laboratories typically participate. Or there may be a perceived lack of time or resources to adequately examine data quality. Regardless of the reason, the lack of QA/QC protocols can lead to the generation and publication of erroneous data. Because the interpretations drawn from the data are primary products to U.S. Geological Survey (USGS) stakeholders, the consequences of publishing erroneous results can be significant. The principal investigator of a scientific study ultimately is responsible for the quality and interpretation of the project's findings, and thus must also play a role in the understanding, implementation, and presentation of QA/QC information about the data. Although occasionally ignored, QA/QC protocols apply not only to procedures in the laboratory but also in the initial planning of a research study and throughout the life of the project. Many of the tenets of developing a sound QA/QC program or protocols also parallel the core concepts of developing a good study: What is the main objective of the study? Will the methods selected provide data of enough resolution to answer the hypothesis? How should samples be collected? Are there known or unknown artifacts or contamination sources in the sampling and analysis methods? Assessing data quality requires communication between the scientists responsible for designing the study and those collecting samples, analyzing samples, treating data, and interpreting results. This primer has been developed to provide basic information and guidance about developing QA/QC protocols for geochemical studies. It is not intended to be a comprehensive guide but rather an introduction to key concepts tied to a list of relevant references for further reading. The guidelines are presented in stepwise order beginning with presampling considerations and continuing through final data interpretation. The goal of this primer is to outline basic QA/QC practices that scientists can use before, during, and after chemical analysis to ensure the validity of the data they collect with the goal of providing defendable results and conclusions.

  6. [THE VIRTUAL CYTOLOGIC SLIDES FOR EXTERNAL EVALUATION OF QUALITY OF IMPLEMENTATION OF CYTOLOGIC ANALYSES IN CLINICAL DIAGNOSTIC LABORATORIES: POSSIBILITIES AND PERSPECTIVES].

    PubMed

    Djangirova, T V; Shabalova, I P; Pronichev, A N; Polyakov, E V

    2015-08-01

    The article considers application of technology of analysis of cytological slides in external quality control of clinical diagnostic laboratories. The advantages of virtual slides are demonstrated against other applied technologies of external evaluation of quality i.e. slide plate and digital micro-photography. The conditions of formation of virtual slides for external evaluation of quality of clinical diagnostic laboratories. The technology of their application is described. The success of practical application of considered technology in the Federal system of external evaluation of quality is emphasized. PMID:26596044

  7. Hydraulics, Sedimentation, and Erosion Control Laboratory Application For Product Testing

    E-print Network

    for each Soil Retention Blanket, Bonded Fiber Matrix (BFM), and Hydraulic Mulch $ 7,500.00 product testedHSECL Hydraulics, Sedimentation, and Erosion Control Laboratory Application For Product Testing Tx will be included on the TxDOT Approved Product List for erosion and sediment control materials. The Approved

  8. INVESTIGATIONS IN fISH CONTROL I. Laboratories and methods

    E-print Network

    INVESTIGATIONS IN fISH CONTROL I. Laboratories and methods for screening fish-control chemicals 2. Preliminary observations on the toxicity of antimycin A to fish and other aquatic animals United States Department of the Interior Fish and Wildlife Service Bureau of Sport Fisheries and Wildlife #12;Bureau

  9. Architectures for mission control at the Jet Propulsion Laboratory

    NASA Technical Reports Server (NTRS)

    Davidson, Reger A.; Murphy, Susan C.

    1992-01-01

    JPL is currently converting to an innovative control center data system which is a distributed, open architecture for telemetry delivery and which is enabling advancement towards improved automation and operability, as well as new technology, in mission operations at JPL. The scope of mission control within mission operations is examined. The concepts of a mission control center and how operability can affect the design of a control center data system are discussed. Examples of JPL's mission control architecture, data system development, and prototype efforts at the JPL Operations Engineering Laboratory are provided. Strategies for the future of mission control architectures are outlined.

  10. Infection control in the pulmonary function test laboratory

    PubMed Central

    Rasam, Shweta Amol; Apte, Komalkirti Keshavkiran; Salvi, Sundeep Santosh

    2015-01-01

    Pulmonary function testing plays a crucial role in the diagnostic evaluation of patients with lung diseases. Cases of cross infection acquired from the pulmonary function laboratory, although rare, have been reported from various countries. It is therefore imperative to identify the risks and potential organisms implicated in cross infections in a pulmonary function test (PFT) laboratory and implement better and more effective infection control procedures, which will help in preventing cross infections. The infrastructure, the daily patient flow, and the prevalent disinfection techniques used in a PFT laboratory, all play a significant role in transmission of infections. Simple measures to tackle the cross infection potential in a PFT laboratory can help reduce this risk to a bare minimum. Use of specialized techniques and equipment can also be of much use in a set up that has a high turnover of patients. This review aims at creating awareness about the possible pathogens and situations commonly encountered in a PFT laboratory. We have attempted to suggest some relevant and useful infection control measures with regard to disinfection, sterilization, and patient planning and segregation to help minimize the risk of cross infections in a PFT laboratory. The review also highlights the lacuna in the current scenario of PFT laboratories in India and the need to develop newer and better methods of infection control, which will be more user-friendly and cost effective. Further studies to study the possible pathogens in a PFT laboratory and evaluate the prevalent infection control strategies will be needed to enable us to draw more precious conclusions, which can lead to more relevant, contextual recommendations for cross infections control in PFT lab in India. PMID:26180386

  11. A primer on the cost of quality for improvement of laboratory and pathology specimen processes.

    PubMed

    Carlson, Richard O; Amirahmadi, Fazlollaah; Hernandez, James S

    2012-09-01

    In today's environment, many laboratories and pathology practices are challenged to maintain or increase their quality while simultaneously lowering their overall costs. The cost of improving specimen processes is related to quality, and we demonstrate that actual costs can be reduced by designing "quality at the source" into the processes. Various costs are hidden along the total testing process, and we suggest ways to identify opportunities to reduce cost by improving quality in laboratories and pathology practices through the use of Lean, Six Sigma, and industrial engineering. PMID:22912350

  12. 42 CFR 84.41 - Quality control plans; contents.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... management of quality, including: (1) Requirements for the production of quality data and the use of quality... accordance with 5 U.S.C. 552(a) and 1 CFR part 51. Copies may be obtained from DODSSP, Standardization... 42 Public Health 1 2011-10-01 2011-10-01 false Quality control plans; contents. 84.41 Section...

  13. 14 CFR 21.147 - Changes in quality control system.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Changes in quality control system. 21.147 Section 21.147 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION... quality control system. After the issue of a production certificate, each change to the quality...

  14. Groundwater-quality and quality-control data for two monitoring wells near Pavillion, Wyoming, April and May 2012

    USGS Publications Warehouse

    Wright, Peter R.; McMahon, Peter B.; Mueller, David K.; Clark, Melanie L.

    2012-01-01

    In June 2010, the U.S. Environmental Protection Agency installed two deep monitoring wells (MW01 and MW02) near Pavillion, Wyoming, to study groundwater quality. During April and May 2012, the U.S Geological Survey, in cooperation with the Wyoming Department of Environmental Quality, collected groundwater-quality data and quality-control data from monitoring well MW01 and, following well redevelopment, quality-control data for monitoring well MW02. Two groundwater-quality samples were collected from well MW01—one sample was collected after purging about 1.5 borehole volumes, and a second sample was collected after purging 3 borehole volumes. Both samples were collected and processed using methods designed to minimize atmospheric contamination or changes to water chemistry. Groundwater-quality samples were analyzed for field water-quality properties (water temperature, pH, specific conductance, dissolved oxygen, oxidation potential); inorganic constituents including naturally occurring radioactive compounds (radon, radium-226 and radium-228); organic constituents; dissolved gasses; stable isotopes of methane, water, and dissolved inorganic carbon; and environmental tracers (carbon-14, chlorofluorocarbons, sulfur hexafluoride, tritium, helium, neon, argon, krypton, xenon, and the ratio of helium-3 to helium-4). Quality-control sample results associated with well MW01 were evaluated to determine the extent to which environmental sample analytical results were affected by bias and to evaluate the variability inherent to sample collection and laboratory analyses. Field documentation, environmental data, and quality-control data for activities that occurred at the two monitoring wells during April and May 2012 are presented.

  15. Quality Control for RNA-Seq (QuaCRS): An Integrated Quality Control Pipeline

    PubMed Central

    Kroll, Karl W; Mokaram, Nima E; Pelletier, Alexander R; Frankhouser, David E; Westphal, Maximillian S; Stump, Paige A; Stump, Cameron L; Bundschuh, Ralf; Blachly, James S; Yan, Pearlly

    2014-01-01

    QuaCRS (Quality Control for RNA-Seq) is an integrated, simplified quality control (QC) system for RNA-seq data that allows easy execution of several open-source QC tools, aggregation of their output, and the ability to quickly identify quality issues by performing meta-analyses on QC metrics across large numbers of samples in different studies. It comprises two main sections. First is the QC Pack wrapper, which executes three QC tools: FastQC, RNA-SeQC, and selected functions from RSeQC. Combining these three tools into one wrapper provides increased ease of use and provides a much more complete view of sample data quality than any individual tool. Second is the QC database, which displays the resulting metrics in a user-friendly web interface. It was designed to allow users with less computational experience to easily generate and view QC information for their data, to investigate individual samples and aggregate reports of sample groups, and to sort and search samples based on quality. The structure of the QuaCRS database is designed to enable expansion with additional tools and metrics in the future. The source code for not-for-profit use and a fully functional sample user interface with mock data are available at http://bioserv.mps.ohio-state.edu/QuaCRS/. PMID:25368506

  16. Tools for quality control of fingerprint databases

    NASA Astrophysics Data System (ADS)

    Swann, B. Scott; Libert, John M.; Lepley, Margaret A.

    2010-04-01

    Integrity of fingerprint data is essential to biometric and forensic applications. Accordingly, the FBI's Criminal Justice Information Services (CJIS) Division has sponsored development of software tools to facilitate quality control functions relative to maintaining its fingerprint data assets inherent to the Integrated Automated Fingerprint Identification System (IAFIS) and Next Generation Identification (NGI). This paper provides an introduction of two such tools. The first FBI-sponsored tool was developed by the National Institute of Standards and Technology (NIST) and examines and detects the spectral signature of the ridge-flow structure characteristic of friction ridge skin. The Spectral Image Validation/Verification (SIVV) utility differentiates fingerprints from non-fingerprints, including blank frames or segmentation failures erroneously included in data; provides a "first look" at image quality; and can identify anomalies in sample rates of scanned images. The SIVV utility might detect errors in individual 10-print fingerprints inaccurately segmented from the flat, multi-finger image acquired by one of the automated collection systems increasing in availability and usage. In such cases, the lost fingerprint can be recovered by re-segmentation from the now compressed multi-finger image record. The second FBI-sponsored tool, CropCoeff was developed by MITRE and thoroughly tested via NIST. CropCoeff enables cropping of the replacement single print directly from the compressed data file, thus avoiding decompression and recompression of images that might degrade fingerprint features necessary for matching.

  17. Quality control of VLT-UVES data

    NASA Astrophysics Data System (ADS)

    Hanuschik, Reinhard W.; Kaufer, Andreas; Modigliani, Andrea; D'Odorico, Sandro; Dekker, Hans

    2002-12-01

    UVES is the UV-Visual high-resolution echelle spectrograph mounted at the 8.2m Kueyen (UT2) telescope of the ESO Very Large Telescope. Its data products are pipeline-processed and quality checked by the Data Flow Operations Group (often known as QC Garching). Calibration data are processed to create calibration products and to extract Quality Control (QC) parameters. These parameters provide instrument health checks and monitor instrument performance. Typical UVES QC parameters are: bias level, read-out-noise, dark current of the three CCD detectors used in the instrument, rms of dispersion, resolving power, CCD pixel-to-pixel gain structure, instrument efficiency. The measured data are fed into a database, compared to earlier data, trended over time and published on the web (http://www.eso.org/qc/index_uves.html). The QC system has evolved with time and proven to be extremely useful. Some examples are given which highlight the impact of careful QC on instrument performance.

  18. Protein quality control at the plasma membrane

    PubMed Central

    Okiyoneda, Tsukasa; Apaja, Pirjo M.; Lukacs, Gergely L.

    2011-01-01

    Cellular proteostasis (or protein homeostasis) depends on the timely folding and disposal of conformationally damaged polypeptides during their life span at all subcellular locations. This process is particularly important for membrane proteins confined to the cell surface with critical regulatory role in cellular homoeostasis and intercellular communication. Accumulating evidences indicate that membrane proteins exported from the endoplasmic reticulum (ER) are subjected to peripheral quality control (QC) along the late secretory and endocytic pathways, as well as at the plasma membrane (PM). Recently identified components of the PM QC recognition and effector mechanisms responsible for ubiquitination and lysosomal degradation of conformationally damaged PM proteins uncovered striking similarities to and differences from that of the ER QC machinery. Possible implications of the peripheral protein QC activity in phenotypic modulation of conformational diseases are also outlined. PMID:21571517

  19. New virtual laboratories presenting advanced motion control concepts

    NASA Astrophysics Data System (ADS)

    Goubej, Martin; Krej?í, Alois; Reitinger, Jan

    2015-11-01

    The paper deals with development of software framework for rapid generation of remote virtual laboratories. Client-server architecture is chosen in order to employ real-time simulation core which is running on a dedicated server. Ordinary web browser is used as a final renderer to achieve hardware independent solution which can be run on different target platforms including laptops, tablets or mobile phones. The provided toolchain allows automatic generation of the virtual laboratory source code from the configuration file created in the open- source Inkscape graphic editor. Three virtual laboratories presenting advanced motion control algorithms have been developed showing the applicability of the proposed approach.

  20. Difficulties implementing a quality assurance program at a national laboratory

    SciTech Connect

    Bussolini, P.L.

    1989-01-01

    Personnel who perform scientific research are highly educated, highly motivated professionals who are often leaders in their fields. A recent survey of researchers at Los Alamos shows that they like freedom and peer recognition, and dislike red tape. Rigid, prescriptive quality assurance programs are often fail because they are perceived to limit freedom and peer recognition and enhance red tape. This paper will present some of the reasons for research personnel to have rebelled against quality assurance programs and will offer suggestions for the development of a meaningful and successful quality program.

  1. Mitochondrial Quality Control as a Therapeutic Target.

    PubMed

    Suliman, Hagir B; Piantadosi, Claude A

    2016-01-01

    In addition to oxidative phosphorylation (OXPHOS), mitochondria perform other functions such as heme biosynthesis and oxygen sensing and mediate calcium homeostasis, cell growth, and cell death. They participate in cell communication and regulation of inflammation and are important considerations in aging, drug toxicity, and pathogenesis. The cell's capacity to maintain its mitochondria involves intramitochondrial processes, such as heme and protein turnover, and those involving entire organelles, such as fusion, fission, selective mitochondrial macroautophagy (mitophagy), and mitochondrial biogenesis. The integration of these processes exemplifies mitochondrial quality control (QC), which is also important in cellular disorders ranging from primary mitochondrial genetic diseases to those that involve mitochondria secondarily, such as neurodegenerative, cardiovascular, inflammatory, and metabolic syndromes. Consequently, mitochondrial biology represents a potentially useful, but relatively unexploited area of therapeutic innovation. In patients with genetic OXPHOS disorders, the largest group of inborn errors of metabolism, effective therapies, apart from symptomatic and nutritional measures, are largely lacking. Moreover, the genetic and biochemical heterogeneity of these states is remarkably similar to those of certain acquired diseases characterized by metabolic and oxidative stress and displaying wide variability. This biologic variability reflects cell-specific and repair processes that complicate rational pharmacological approaches to both primary and secondary mitochondrial disorders. However, emerging concepts of mitochondrial turnover and dynamics along with new mitochondrial disease models are providing opportunities to develop and evaluate mitochondrial QC-based therapies. The goals of such therapies extend beyond amelioration of energy insufficiency and tissue loss and entail cell repair, cell replacement, and the prevention of fibrosis. This review summarizes current concepts of mitochondria as disease elements and outlines novel strategies to address mitochondrial dysfunction through the stimulation of mitochondrial biogenesis and quality control. PMID:26589414

  2. 10 CFR 26.167 - Quality assurance and quality control.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...laboratory information management system, or computer, and...tests that have the dynamic range of 2 to 12 to...paper that have a narrow dynamic range and do not support...appropriate levels of management. (2) If a...

  3. 10 CFR 26.167 - Quality assurance and quality control.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...laboratory information management system, or computer, and...tests that have the dynamic range of 2 to 12 to...paper that have a narrow dynamic range and do not support...appropriate levels of management. (2) If a...

  4. 10 CFR 26.167 - Quality assurance and quality control.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...laboratory information management system, or computer, and...tests that have the dynamic range of 2 to 12 to...paper that have a narrow dynamic range and do not support...appropriate levels of management. (2) If a...

  5. 10 CFR 26.167 - Quality assurance and quality control.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...laboratory information management system, or computer, and...tests that have the dynamic range of 2 to 12 to...paper that have a narrow dynamic range and do not support...appropriate levels of management. (2) If a...

  6. 10 CFR 26.167 - Quality assurance and quality control.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...laboratory information management system, or computer, and...tests that have the dynamic range of 2 to 12 to...paper that have a narrow dynamic range and do not support...appropriate levels of management. (2) If a...

  7. 40 CFR 75.21 - Quality assurance and quality control requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false Quality assurance and quality control requirements. 75.21 Section 75.21 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTINUOUS EMISSION MONITORING Operation and Maintenance Requirements § 75.21 Quality assurance and quality...

  8. QUALITY ASSURANCE AND QUALITY CONTROL IN THE DEVELOPMENT AND APPLICATION OF GROUND-WATER MODELS

    EPA Science Inventory

    This report provides background information on quality assurance and defines the role of quality assurance and quality control in grounder modeling. unctional and practical quality-assurance methodology is presented which is written from the perspective of the model user and the ...

  9. 40 CFR 75.21 - Quality assurance and quality control requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 17 2012-07-01 2012-07-01 false Quality assurance and quality control requirements. 75.21 Section 75.21 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTINUOUS EMISSION MONITORING Operation and Maintenance Requirements § 75.21 Quality assurance and quality...

  10. 40 CFR 75.21 - Quality assurance and quality control requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 17 2013-07-01 2013-07-01 false Quality assurance and quality control requirements. 75.21 Section 75.21 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTINUOUS EMISSION MONITORING Operation and Maintenance Requirements § 75.21 Quality assurance and quality...

  11. Weight control and restraint of laboratory rats

    NASA Technical Reports Server (NTRS)

    Hilado, C. J.; Van Breda Kolff, K.

    1979-01-01

    The use of restrained and confined rats in some procedures used in combustion toxicology introduces the problems of obtaining rats of the appropriate size for the apparatus, and of identifying any artifacts resulting from the use of restraint alone. Feeding studies indicate that controlled feeding of fast-growing strains such as the Sprague-Dawley can hold rat size essentially constant for significant periods of time. The undesirable aspects are the need to cage the animals individually, with resultant psychological as well as metabolic effects. Restraint studies of slow-growing strains such as the Fischer 344 indicate that denying access to food and water for periods of several hours at a time interrupts normal gain only temporarily.

  12. Sandia National Laboratories, California Air Quality Program annual report.

    SciTech Connect

    Gardizi, Leslee P.; Smith, Richard

    2009-06-01

    The annual program report provides detailed information about all aspects of the SNL/CA Air Quality Program. It functions as supporting documentation to the SNL/CA Environmental Management System Program Manual. The program report describes the activities undertaken during the past year, and activities planned in future years to implement the Air Quality Program, one of six programs that supports environmental management at SNL/CA.

  13. Water Quality & Pollutant Source Monitoring: Field and Laboratory Procedures. Training Manual.

    ERIC Educational Resources Information Center

    Office of Water Program Operations (EPA), Cincinnati, OH. National Training and Operational Technology Center.

    This training manual presents material on techniques and instrumentation used to develop data in field monitoring programs and related laboratory operations concerned with water quality and pollution monitoring. Topics include: collection and handling of samples; bacteriological, biological, and chemical field and laboratory methods; field…

  14. Audit of the Department of Energy`s Commercial Laboratory Quality Assurance Evaluation Program

    SciTech Connect

    1995-06-01

    The Department of Energy (Department), through its contractors, contracts with commercial analytical laboratories for the analysis of samples related to environmental management activities and worker health and safety programs. Over 100 commercial laboratories located throughout the United States perform sample analyses for the Department, Because of problems identified during previous audit work, we initiated our audit to determine whether the Department`s commercial laboratory quality assurance evaluation program was effective and efficient.

  15. Towards Quality-of-Service Control of Networked Control Systems: A Switched Time Delay Systems Approach

    E-print Network

    Hirche, Sandra

    Towards Quality-of-Service Control of Networked Control Systems: A Switched Time Delay Systems of a networked control system (NCS) strongly depends on the communication quality in terms of time delay approach to conjointly control the NCS as well as the communication quality on basis of the QoS concept. We

  16. 40 CFR 81.32 - Puget Sound Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...2011-07-01 2011-07-01 false Puget Sound Intrastate Air Quality Control Region...Quality Control Regions § 81.32 Puget Sound Intrastate Air Quality Control Region. The Puget Sound Intrastate Air Quality Control...

  17. 40 CFR 81.32 - Puget Sound Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...2012-07-01 2012-07-01 false Puget Sound Intrastate Air Quality Control Region...Quality Control Regions § 81.32 Puget Sound Intrastate Air Quality Control Region. The Puget Sound Intrastate Air Quality Control...

  18. 40 CFR 81.32 - Puget Sound Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...2010-07-01 2010-07-01 false Puget Sound Intrastate Air Quality Control Region...Quality Control Regions § 81.32 Puget Sound Intrastate Air Quality Control Region. The Puget Sound Intrastate Air Quality Control...

  19. 40 CFR 81.32 - Puget Sound Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...2014-07-01 2014-07-01 false Puget Sound Intrastate Air Quality Control Region...Quality Control Regions § 81.32 Puget Sound Intrastate Air Quality Control Region. The Puget Sound Intrastate Air Quality Control...

  20. 40 CFR 81.32 - Puget Sound Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...2013-07-01 2013-07-01 false Puget Sound Intrastate Air Quality Control Region...Quality Control Regions § 81.32 Puget Sound Intrastate Air Quality Control Region. The Puget Sound Intrastate Air Quality Control...

  1. Remote Control Laboratory Using EJS Applets and TwinCAT Programmable Logic Controllers

    ERIC Educational Resources Information Center

    Besada-Portas, E.; Lopez-Orozco, J. A.; de la Torre, L.; de la Cruz, J. M.

    2013-01-01

    This paper presents a new methodology to develop remote laboratories for systems engineering and automation control courses, based on the combined use of TwinCAT, a laboratory Java server application, and Easy Java Simulations (EJS). The TwinCAT system is used to close the control loop for the selected plants by means of programmable logic…

  2. Graduate Lectures and Problems in Quality Control and Engineering Statistics

    E-print Network

    Vardeman, Stephen B.

    Graduate Lectures and Problems in Quality Control and Engineering Statistics: Theory and Methods To Accompany Statistical Quality Assurance Methods for Engineers by Vardeman and Jobe Stephen B. Vardeman V2;Chapter 3 An Introduction to Discrete Stochastic Control Theory/Minimum Variance Control Section 3.6 of V

  3. Quality control in a deterministic manufacturing environment

    SciTech Connect

    Barkman, W.E.; Babelay, E.F.; De Mint, P.D.; Lewis, J.C.; Woodard, L.M.

    1985-01-24

    An approach for establishing quality control in processes which exhibit undesired continual or intermittent excursions in key process parameters is discussed. The method is called deterministic manufacturing, and it is designed to employ automatic monitoring of the key process variables for process certification, but utilizes only sample certification of the process output to verify the validity of the measurement process. The system utilizes a local minicomputer to sample the appropriate process parameters that describe the condition of the machine tool, the cutting process, and the computer numerical control system. Sampled data are pre-processed by the minicomputer and then sent to a host computer that maintains a permanent data base describing the manufacturing conditions for each work piece. Parts are accepted if the various parameters remain within the required limits during the machining cycle. The need for additional actions is flagged if limits are exceeded. With this system it is possible to retrospectively examine the process status just prior to the occurrence of a problem. (LEW)

  4. Bacteriological Methods in Water Quality Control Programs. Training Manual.

    ERIC Educational Resources Information Center

    Office of Water Program Operations (EPA), Cincinnati, OH. National Training and Operational Technology Center.

    This training manual presents material on basic bacteriological laboratory procedures as required by Federal Register Water Quality Guidelines. Course topics include: characteristics, occurrences, and significance of bacterial indicators of pollution; bacteriological water quality standards and criteria; collection and handling of samples;…

  5. Bacteriological Methods in Water Quality Control Programs. Instructor's Guide.

    ERIC Educational Resources Information Center

    Office of Water Program Operations (EPA), Cincinnati, OH. National Training and Operational Technology Center.

    This instructor's manual presents material on basic bacteriological laboratory procedures as required by Federal Register Water Quality Guidelines. Course topics include: characteristics, occurrences, and significance of bacterial indicators of pollution; bacteriological water quality standards and criteria; collection and handling of samples;…

  6. Chapter 5: Quality assurance/quality control in stormwater sampling

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Sampling the quality of stormwater presents unique challenges because stormwater flow is relatively short-lived with drastic variability. Furthermore, storm events often occur with little advance warning, outside conventional work hours, and under adverse weather conditions. Therefore, most stormwat...

  7. TECHNICAL GUIDANCE DOCUMENT: QUALITY ASSURANCE AND QUALITY CONTROL FOR WASTE CONTAINMENT FACILITIES

    EPA Science Inventory

    This Technical Guidance Document provides comprehensive guidance on procedures for quality assurance and quality control for waste containment facilities. he document includes a discussion of principles and concepts, compacted soil liners, soil drainage systems, geosynthetic drai...

  8. QUALITY ASSURANCE AND QUALITY CONTROL FOR WASTE CONTAINMENT FACILITIES. Project Summary

    EPA Science Inventory

    It is generally agreed that both quality assurance (QA) and quality control (QC) are essential to the proper installation and eventual performance of environmentally safe and secure waste containment systems. Even further, there are both manufacturing and construction aspects to...

  9. TECHNICAL GUIDANCE DOCUMENT: QUALITY ASSURANCE AND QUALITY CONTROL FOR WASTE CONTAINMENT FACILITIES

    EPA Science Inventory

    This Technical Guidance Document provides comprehensive guidance on procedures for quality assurance and quality control for waste containment facilities. The document includes a discussion of principles and concepts, compacted soil liners, soil drainage systems, geosynthetic dr...

  10. 77 FR 41188 - Clinical Laboratory Improvement Advisory Committee (CLIAC)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-12

    ... HUMAN SERVICES Centers for Disease Control and Prevention Clinical Laboratory Improvement Advisory... related to improvement in clinical laboratory quality and laboratory medicine practice and specific...-centeredness of laboratory services; revisions to the standards under which clinical laboratories are...

  11. 78 FR 6330 - Clinical Laboratory Improvement Advisory Committee (CLIAC)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-30

    ... HUMAN SERVICES Centers for Disease Control and Prevention Clinical Laboratory Improvement Advisory... related to improvement in clinical laboratory quality and laboratory medicine practice and specific... laboratory services; revisions to the standards under which clinical laboratories are regulated; the...

  12. Providing Quality Laboratories to Long-Distance Educational Programs.

    ERIC Educational Resources Information Center

    Gammon, Tammy; Sutton, John

    2003-01-01

    North Carolina State University (UNC) has been on the forefront of long-distance education by offering a Bachelor of Science in Engineering with a Mechatronics Concentration at its remote campus located at UNC Asheville. The program demonstrates that long-distance laboratories are feasible and should not be a stumbling block to offering…

  13. A Toolkit for Building Energy Consumption Data Quality Assurance/Quality Control 

    E-print Network

    Baltazar, J.C.

    2011-01-01

    for Building Energy Consumption Data Quality Assurance/Quality Control Dr. Juan-Carlos Baltazar, Dr. Jing Ji, Hiroko Masuda, Yifu Sun Dr. David E. Claridge ESL-IC-11-10-30 Proceedings of the Eleventh International Conference Enhanced... Building Operations, New York City, October 18-20, 2011 ICEBO 2011 ? New York JCB/ESL Outline ? Motivation ? Building Energy Data Quality Assurance/Quality Control (QA/QC) Project ? Tool Development ? Inputs ? Modules ? Outputs...

  14. Enhancement and quality control of GOES images

    NASA Astrophysics Data System (ADS)

    Jentoft-Nilsen, Marit; Palaniappan, Kannappan; Hasler, A. Frederick; Chesters, Dennis

    1996-10-01

    The new generation of Geostationary Operational Environmental Satellites (GOES) have an imager instrument with five multispectral bands of high spatial resolution,and very high dynamic range radiance measurements with 10-bit precision. A wide variety of environmental processes can be observed at unprecedented time scales using the new imager instrument. Quality assurance and feedback to the GOES project office is performed using rapid animation at high magnification, examining differences between successive frames, and applying radiometric and geometric correction algorithms. Missing or corrupted scanline data occur unpredictably due to noise in the ground based receiving system. Smooth high resolution noise-free animations can be recovered using automatic techniques even from scanline scratches affecting more than 25 percent of the dataset. Radiometric correction using the local solar zenith angle was applied to the visible channel to compensate for time- of-day illumination variations to produce gain-compensated movies that appear well-lit from dawn to dusk and extend the interval of useful image observations by more than two hours. A time series of brightness histograms displays some subtle quality control problems in the GOES channels related to rebinning of the radiance measurements. The human visual system is sensitive to only about half of the measured 10- bit dynamic range in intensity variations, at a given point in a monochrome image. In order to effectively use the additional bits of precision and handle the high data rate, new enhancement techniques and visualization tools were developed. We have implemented interactive image enhancement techniques to selectively emphasize different subranges of the 10-bits of intensity levels. Improving navigational accuracy using registration techniques and geometric correction of scanline interleaving errors is a more difficult problem that is currently being investigated.

  15. A controllable laboratory stock market for modeling real stock markets

    NASA Astrophysics Data System (ADS)

    An, Kenan; Li, Xiaohui; Yang, Guang; Huang, Jiping

    2013-10-01

    Based on the different research approaches, econophysics can be divided into three directions: empirical econophysics, computational econophysics, and experimental econophysics. Because empirical econophysics lacks controllability that is needed to study the impacts of different external conditions and computational econophysics has to adopt artificial decision-making processes that are often deviated from those of real humans, experimental econophysics tends to overcome these problems by offering controllability and using real humans in laboratory experiments. However, to our knowledge, the existing laboratory experiments have not convincingly reappeared the stylized facts (say, scaling) that have been revealed for real economic/financial markets by econophysicists. A most important reason is that in these experiments, discrete trading time makes these laboratory markets deviated from real markets where trading time is naturally continuous. Here we attempt to overcome this problem by designing a continuous double-auction stock-trading market and conducting several human experiments in laboratory. As an initial work, the present artificial financial market can reproduce some stylized facts related to clustering and scaling. Also, it predicts some other scaling in human behavior dynamics that is hard to achieve in real markets due to the difficulty in getting the data. Thus, it becomes possible to study real stock markets by conducting controlled experiments on such laboratory stock markets producing high frequency data.

  16. Live births achieved via IVF are increased by improvements in air quality and laboratory environment.

    PubMed

    Heitmann, Ryan J; Hill, Micah J; James, Aidita N; Schimmel, Tim; Segars, James H; Csokmay, John M; Cohen, Jacques; Payson, Mark D

    2015-09-01

    Infertility is a common disease, which causes many couples to seek treatment with assisted reproduction techniques. Many factors contribute to successful assisted reproduction technique outcomes. One important factor is laboratory environment and air quality. Our facility had the unique opportunity to compare consecutively used, but separate assisted reproduction technique laboratories, as a result of a required move. Environmental conditions were improved by strategic engineering designs. All other aspects of the IVF laboratory, including equipment, physicians, embryologists, nursing staff and protocols, were kept constant between facilities. Air quality testing showed improved air quality at the new IVF site. Embryo implantation (32.4% versus 24.3%; P < 0.01) and live birth (39.3% versus 31.8%, P < 0.05) were significantly increased in the new facility compared with the old facility. More patients met clinical criteria and underwent mandatory single embryo transfer on day 5 leading to both a reduction in multiple gestation pregnancies and increased numbers of vitrified embryos per patient with supernumerary embryos available. Improvements in IVF laboratory conditions and air quality had profound positive effects on laboratory measures and patient outcomes. This study further strengthens the importance of the laboratory environment and air quality in the success of an IVF programme. PMID:26194882

  17. Science Laboratories and Indoor Air Quality in Schools. Technical Bulletin.

    ERIC Educational Resources Information Center

    Jacobs, Bruce W.

    Some of the issues surrounding the indoor air quality (IAQ) problems presented by science labs are discussed. Described are possible contaminants in labs, such as chemicals and biological organisms, and ways to lessen accidents arising from these sources are suggested. Some of the factors contributing to comfort, such as temperature levels, are…

  18. 21 CFR 111.117 - What quality control operations are required for equipment, instruments, and controls?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...CONSUMPTION CURRENT GOOD MANUFACTURING PRACTICE IN MANUFACTURING, PACKAGING, LABELING, OR HOLDING OPERATIONS FOR DIETARY SUPPLEMENTS Production and Process Control System: Requirements for Quality Control § 111.117 What quality...

  19. Millikan's Oil-Drop Experiment as a Remotely Controlled Laboratory

    ERIC Educational Resources Information Center

    Eckert, Bodo; Grober, Sebastian; Vetter, Martin; Jodl, Hans-Jorg

    2012-01-01

    The Millikan oil-drop experiment, to determine the elementary electrical charge e and the quantization of charge Q = n [middle dot] e, is an essential experiment in physics teaching but it is hardly performed in class for several reasons. Therefore, we offer this experiment as a remotely controlled laboratory (RCL). We describe the interactivity…

  20. MaterialsProcessDesign and ControlLaboratory Cornell University

    E-print Network

    Zabaras, Nicholas J.

    Materials Process Design and Control Laboratory Sibley School of Mechanical and Aerospace Engineering 101-535 turbofan Nickel-base superalloy turbine disk Superalloy microstructure Sheared ' precipitates Pairs of edge and Design: An Information Theoretic Approach 4 Rolls-Royce RB211-535 turbofan Nickel-base superalloy turbine

  1. [Quality use of commercial laboratory for clinical testing services - considering laboratory's role].

    PubMed

    Ogawa, Shinji

    2014-12-01

    The number of commercial laboratories for clinical testing in Japan run privately has decreased to about 30 companies, and their business is getting tougher. Branch Lab. and FMS businesses have not expanded recently due to the new reimbursement system which adds an additional sample management fee, becoming effective in 2010. This presentation gives an outline of each role for hospital and commercial laboratories, and their pros & cons considering the current medical situation. Commercial laboratories have investigated how to utilize ICT systems for sharing test information between hospitals and our facilities. It would be very helpful to clarify issues for each hospital. We will develop and create new values for clinical laboratory testing services and forge mutually beneficial relationships with medical institutions. (Review). PMID:25823243

  2. Quality control on radiant heaters manufacture

    NASA Astrophysics Data System (ADS)

    González, Daniel A.; Madruga, Francisco J.; Ibarra-Castanedo, Clemente; Conde, Olga; López-Higuera, Jose M.

    2006-04-01

    An inspection process of radiant heaters is presented in this paper. The proposed non destructive testing and evaluation (NDT and E) technique for defect assessment of radiant heaters is based on infrared thermography images properly acquired and processed. The technique can be used in on-line fabrication quality control radiant heaters manufacturing processes. By exciting the heater with a very short electrical pulse, a sequence of thermographic images is captured by an infrared camera and then analyzed. Regardless of the electrical excitation applied to the heating element of the heater, the electrical power supplied will dissipate at the resistor. Provided enough spatial resolution, the heaters could be tested with an infrared camera capturing the radiated heat. The analysis of the heating wire during the heating flank shows differences among pixels corresponding to defective points and pixels belonging to non-defective areas of the wire. The automation is provided by the development of an algorithm that looks for the slope of the heating evolution of each pixel. A Radon Transform based algorithm is here proposed to reduce human intervention providing just one image where an operator could quickly locate possible defects.

  3. Toward standardising gamma camera quality control procedures

    NASA Astrophysics Data System (ADS)

    Alkhorayef, M. A.; Alnaaimi, M. A.; Alduaij, M. A.; Mohamed, M. O.; Ibahim, S. Y.; Alkandari, F. A.; Bradley, D. A.

    2015-11-01

    Attaining high standards of efficiency and reliability in the practice of nuclear medicine requires appropriate quality control (QC) programs. For instance, the regular evaluation and comparison of extrinsic and intrinsic flood-field uniformity enables the quick correction of many gamma camera problems. Whereas QC tests for uniformity are usually performed by exposing the gamma camera crystal to a uniform flux of gamma radiation from a source of known activity, such protocols can vary significantly. Thus, there is a need for optimization and standardization, in part to allow direct comparison between gamma cameras from different vendors. In the present study, intrinsic uniformity was examined as a function of source distance, source activity, source volume and number of counts. The extrinsic uniformity and spatial resolution were also examined. Proper standard QC procedures need to be implemented because of the continual development of nuclear medicine imaging technology and the rapid expansion and increasing complexity of hybrid imaging system data. The present work seeks to promote a set of standard testing procedures to contribute to the delivery of safe and effective nuclear medicine services.

  4. Timing control improves seabed survey data quality

    SciTech Connect

    Green, R.

    1996-04-01

    Seateam has completed development of and field-proven the Dolphin data acquisition and timing system for high-density surveys offshore. The Dolphin project was initiated to improve quality control of survey sensor data and ensure time synchronization, thus leading to faster turnaround of seabed terrain information. Data received from survey sensors is asynchronous, so the system must provide for data correlation. This includes establishment of data latency, i.e., the time difference between data creation and timing of the message at first-byte arrival at the recording system. Until recently, asynchronous data from multiple sensors was collected by a single computer, regardless of whether it had additional intelligent or non-intelligent serial cards. This computer was fully responsible for time stamping all incoming data, plus associated storage and distribution. Though this initially sufficed and is still applicable to low-density data, increasingly larger data volumes required an associated boost in the capability to time stamp data prior to eventual correction.

  5. Surface quality control in diamond abrasive finishing

    NASA Astrophysics Data System (ADS)

    Filatov, Yuriy D.; Sidorko, Volodymyr I.; Filatov, Olexandr Yu.; Yaschuk, Vasil P.; Heisel, Uwe; Storchak, Michael

    2009-06-01

    The paper presents a procedure for measuring laser radiation reflection and scattering coefficients of polished surface. A relation between the scattered light intensity and the polished surface roughness is studied. It is demonstrated that colorimetric characteristics of non-metallic materials can be determined from the light scattering and reflection coefficients. This work has demonstrated a possibility of and created prerequisites for the development of an express method for tentative assessment of polished surface roughness. Of interest is the use of the ?(Rz) function for the purposes of quality inspection of polished surfaces of natural and synthetic stone and other non-metallic materials. It was established that the most relevant parameter of roughness, which can be defined by the light reflection is Rz. The Dependency of the reflection factor from parameter of roughness Rz was approximated by formula with inaccuracy 5-10%. Inaccuracy of the determination of roughness Rz has formed 1%. It was shown that method of the surface roughness control using the light reflection factor is the most efficient for surfaces with roughness Rz <0.3 microns, typical for finish diamond-abrasive machining.

  6. INVENTORY AND REVIEW OF QUALITY ASSURANCE/QUALITY CONTROL

    E-print Network

    for the Fraser River Basin, the Committee wished to review current protocols as a basis for a comprehensive plan of the Environmental Quality Component of the Fraser River Action Plan (FRAP). This committee is mandated to provide guidance in the area of QA/QC for sampling programs in the Fraser River Basin to ensure: 1) production

  7. Sandia National Laboratories Advanced Simulation and Computing (ASC) software quality plan : ASC software quality engineering practices Version 3.0.

    SciTech Connect

    Turgeon, Jennifer L.; Minana, Molly A.; Hackney, Patricia; Pilch, Martin M.

    2009-01-01

    The purpose of the Sandia National Laboratories (SNL) Advanced Simulation and Computing (ASC) Software Quality Plan is to clearly identify the practices that are the basis for continually improving the quality of ASC software products. Quality is defined in the US Department of Energy/National Nuclear Security Agency (DOE/NNSA) Quality Criteria, Revision 10 (QC-1) as 'conformance to customer requirements and expectations'. This quality plan defines the SNL ASC Program software quality engineering (SQE) practices and provides a mapping of these practices to the SNL Corporate Process Requirement (CPR) 001.3.6; 'Corporate Software Engineering Excellence'. This plan also identifies ASC management's and the software project teams responsibilities in implementing the software quality practices and in assessing progress towards achieving their software quality goals. This SNL ASC Software Quality Plan establishes the signatories commitments to improving software products by applying cost-effective SQE practices. This plan enumerates the SQE practices that comprise the development of SNL ASC's software products and explains the project teams opportunities for tailoring and implementing the practices.

  8. PAS365/PAS6022 Industrial Statistical Modelling Quality Control Problems

    E-print Network

    Jordan, Jonathan

    PAS365/PAS6022 Industrial Statistical Modelling Quality Control Problems 1. A chemical company it is rejected. Suppose the manufacturer regards batches with proportion of defectives 0.01 as of good quality and batches with proportion of defectives 0.06 as of poor quality. If the manufacturer requires no more than

  9. Tree leaf control on low flow water quality in a small Virginia stream

    USGS Publications Warehouse

    Slack, K.V.; Feltz, H.R.

    1968-01-01

    Impaired water quality in a small stream was related to autumn leaf fall from riparian vegetation. Dissolved oxygen and pH decreased, and water color, specific conductance, iron, manganese, and bicarbonate values increased as the rate of leaf fall increased. Similar quality changes occurred in laboratory cultures of tree leaves in filtered stream water, but the five leaf species studied produced widely differing results. Stream quality improved rapidly following channel flushing by storm flow. Organic loading by tree litter can exert significant control on water composition, especially during low flow.

  10. Operation logic and functionality of automatic dose rate and image quality control of conventional fluoroscopy

    SciTech Connect

    Lin, Pei-Jan Paul

    2009-05-15

    New generation of fluoroscopic imaging systems is equipped with spectral shaping filters complemented with sophisticated automatic dose rate and image quality control logic called ''fluoroscopy curve'' or ''trajectory''. Such fluoroscopy curves were implemented first on cardiovascular angiographic imaging systems and are now available on conventional fluoroscopy equipment. This study aims to investigate the control logic operations under the fluoroscopy mode and acquisition mode (equivalent to the legacy spot filming) of a conventional fluoroscopy system typically installed for upper-lower gastrointestinal examinations, interventional endoscopy laboratories, gastrointestinal laboratory, and pain clinics.

  11. Development of laboratory control samples for the ICP-ES determination of nutrient elements in rat tissues

    NASA Astrophysics Data System (ADS)

    Wolnik, Karen A.; Rader, Jeanne I.; Gaston, Cynthia M.; Fricke, Fred L.

    Laboratory control samples have been prepared from rabbit bones and duodenum and from bovine kidney and spleen for use in quality control and development of methodology for the inductively coupled plasma emission spectroscopy (ICP-ES) determination of 9 elements in weanling rat tissues. Analysis by ICP-ES following wet acid digestion was used to characterize these control samples with respect to mineral content and homogeneity. Results of the investigation of alternative pretreatment techniques are included.

  12. Air quality in the assisted reproduction laboratory: a mini-review.

    PubMed

    Morbeck, Dean E

    2015-07-01

    Quality of air in the clinical embryology laboratory is considered critical for high in vitro fertilization (IVF) success rates, yet evidence for best practices is lacking. Predominantly anecdotal reports on relationships between air quality and IVF success rates have resulted in minimal authentic clinical laboratory guidelines or in recommendations that are based on industrial cleanroom particulate standards with little attention to chemical air filtration. As a result, a nascent industry of costly, specialized air handling equipment for IVF laboratories has emerged to provide air quality solutions that have not been clearly assessed or verified. Clinics are embracing such technology because their embryology laboratories have become epicenters of assisted reproductive technology as the practice of IVF has moved to blastocyst transfers and utilization of trophectoderm biopsy for preimplantation genetic testing (PGT). Thus, a laboratory's ability to culture, biopsy, and freeze blastocysts is a rate-limiting step that depends on technical proficiency and a supportive and stable culture environment based on a foundation of high-quality ambient air. This review aims to describe how evidence for the importance of air quality, in particular the role of volatile organic compounds (VOC), has resulted in an evolution of clinical practice that has arguably contributed to improved outcomes. PMID:26238385

  13. Entry Attitude Controller for the Mars Science Laboratory

    NASA Technical Reports Server (NTRS)

    Brugarolas, Paul B.; SanMartin, A. Miguel; Wong, Edward C.

    2007-01-01

    This paper describes the preliminary concept for the RCS 3-axis attitude controller for the exo-atmospheric and guided entry phases of the Mars Science Laboratory Entry, Descend and Landing. The entry controller is formulated as three independent channels in the control frame, which is nominally aligned with the stability frame. Each channel has a feedfoward and a feedback. The feedforward path enables fast response to large bank commands. The feedback path stabilizes the vehicle angle of attack and sideslip around its trim position, and tracks bank commands. The feedback path has a PD/D structure with deadbands that minimizes fuel usage. The performance of this design is demonstrated via simulation.

  14. Building Science Corporation's Building America Quality Control Checklist

    SciTech Connect

    2008-10-05

    The Building America Quality Control Checklist has been developed as both a guide to assist in the transition to high performance home building, and as a simplified tool to be used as part of any builder's on-site quality control procedures.

  15. PLANNING GUIDE FOR EVALUATING AGRICULTURAL NONPOINT SOURCE WATER QUALITY CONTROLS

    EPA Science Inventory

    This manual is a guide for water quality planners in the evaluation and selection of agricultural nonpoint source controls for areas ranging in size from individual farms and subwatersheds to large regions. Such controls are specified in water quality plans developed in response ...

  16. Artificial Intelligence Approach to Support Statistical Quality Control Teaching

    ERIC Educational Resources Information Center

    Reis, Marcelo Menezes; Paladini, Edson Pacheco; Khator, Suresh; Sommer, Willy Arno

    2006-01-01

    Statistical quality control--SQC (consisting of Statistical Process Control, Process Capability Studies, Acceptance Sampling and Design of Experiments) is a very important tool to obtain, maintain and improve the Quality level of goods and services produced by an organization. Despite its importance, and the fact that it is taught in technical and…

  17. 14 CFR 145.211 - Quality control system.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Quality control system. 145.211 Section 145.211 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SCHOOLS AND OTHER CERTIFICATED AGENCIES REPAIR STATIONS Operating Rules § 145.211 Quality control system. (a) A certificated repair station...

  18. 7 CFR 58.733 - Quality control tests.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 3 2013-01-01 2013-01-01 false Quality control tests. 58.733 Section 58.733... Procedures § 58.733 Quality control tests. (a) Chemical analyses. The following chemical analyses shall be... pasteurization by means of the phosphatase test, as well as any other tests necessary to assure good...

  19. 14 CFR 145.211 - Quality control system.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Quality control system. 145.211 Section 145.211 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SCHOOLS AND OTHER CERTIFICATED AGENCIES REPAIR STATIONS Operating Rules § 145.211 Quality control system. (a) A certificated repair station...

  20. 14 CFR 21.147 - Changes in quality control system.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Changes in quality control system. 21.147 Section 21.147 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT CERTIFICATION PROCEDURES FOR PRODUCTS AND PARTS Production Certificates § 21.147 Changes in quality control system. After the issue of...

  1. 7 CFR 58.733 - Quality control tests.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 3 2012-01-01 2012-01-01 false Quality control tests. 58.733 Section 58.733... Procedures § 58.733 Quality control tests. (a) Chemical analyses. The following chemical analyses shall be... pasteurization by means of the phosphatase test, as well as any other tests necessary to assure good...

  2. 7 CFR 58.733 - Quality control tests.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 3 2014-01-01 2014-01-01 false Quality control tests. 58.733 Section 58.733... Procedures § 58.733 Quality control tests. (a) Chemical analyses. The following chemical analyses shall be... pasteurization by means of the phosphatase test, as well as any other tests necessary to assure good...

  3. 42 CFR 84.256 - Quality control requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Quality control requirements. 84.256 Section 84.256 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Special Use Respirators § 84.256 Quality control requirements....

  4. 42 CFR 84.256 - Quality control requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Quality control requirements. 84.256 Section 84.256 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Special Use Respirators § 84.256 Quality control requirements....

  5. 30 CFR 28.31 - Quality control plans; contents.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.31 Quality control plans; contents. (a... these provisions. (b) The sampling plan shall include inspection tests and sampling procedures developed..., Pittsburgh, PA 15250-7954; Telephone: 866-512-1800, http://bookstore.gpo.gov. (c) The sampling...

  6. 46 CFR 164.019-13 - Production quality control requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 6 2012-10-01 2012-10-01 false Production quality control requirements. 164.019-13 Section 164.019-13 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL MATERIALS Personal Flotation Device Components § 164.019-13 Production quality control...

  7. QUALITY ASSURANCE/QUALITY CONTROL MANUAL FOR THE LOWER CAPE FEAR RIVER PROGRAM

    E-print Network

    Mallin, Michael

    QUALITY ASSURANCE/QUALITY CONTROL MANUAL FOR THE LOWER CAPE FEAR RIVER PROGRAM Aquatic Ecology................................................................. 3 8 Multi-parameter Water Quality Meter Operation............................5 9 Aquatic Ecology Ecology Lab Certification Documents Appendix VIII Analysis Methods and SOPs #12;Section 0, Page 1 of 2

  8. The Advanced Controls Program at Oak Ridge National Laboratory

    SciTech Connect

    Knee, H.E.; White, J.D.

    1990-01-01

    The Oak Ridge National Laboratory (ORNL), under sponsorship of the US Department of Energy (DOE), is conducting research that will lead to advanced, automated control of new liquid-metal-reactor (LMR) nuclear power plants. Although this program of research (entitled the Advanced Controls Program'') is focused on LMR technology, it will be capable of providing control design, test, and qualification capability for other advanced reactor designs (e.g., the advanced light water reactor (ALWR) and high temperature gas-cooled reactor (HTGR) designs), while also benefiting existing nuclear plants. The Program will also have applicability to complex, non-nuclear process control environments (e.g., petrochemical, aerospace, etc.). The Advanced Controls Program will support capabilities throughout the entire plant design life cycle, i.e., from the initial interactive first-principle dynamic model development for the process, systems, components, and instruments through advanced control room qualification. The current program involves five principal areas of research activities: (1) demonstrations of advanced control system designs, (2) development of an advanced controls design environment, (3) development of advanced control strategies, (4) research and development (R D) in human-system integration for advanced control system designs, and (5) testing and validation of advanced control system designs. Discussion of the research in these five areas forms the basis of this paper. Also included is a description of the research directions of the program. 8 refs.

  9. International Quality Control Is No Easy Task

    ERIC Educational Resources Information Center

    Contreras, Alan

    2008-01-01

    In early March, the European Quality Assurance Register for Higher Education was established under what is called the Bologna Process. The 46 countries involved in the process seek to improve the quality and assessment of higher education throughout Europe, thus facilitating students' mobility among institutions and countries and enhancing…

  10. VERSATILE PC-BASED DATA ACQUISITION AND CONTROL SYSTEM: AUTOMATION OF EPA'S AIR TOXICS CONTROL LABORATORY

    EPA Science Inventory

    The paper discusses the decision making process which resulted in the selection and configuration of the hardware and software for the Air Toxics Control Laboratory (ATCL) designed and built at EPA's Air and Energy Engineering Research Laboratory, in response to the need for the ...

  11. Nuclear Technology Series. Course 14: Introduction to Quality Assurance/Quality Control.

    ERIC Educational Resources Information Center

    Technical Education Research Center, Waco, TX.

    This technical specialty course is one of thirty-five courses designed for use by two-year postsecondary institutions in five nuclear technician curriculum areas: (1) radiation protection technician, (2) nuclear instrumentation and control technician, (3) nuclear materials processing technician, (4) nuclear quality-assurance/quality-control

  12. Ride quality sensitivity to SAS control law and to handling quality variations

    NASA Technical Reports Server (NTRS)

    Roberts, P. A.; Schmidt, D. K.; Swaim, R. L.

    1976-01-01

    The RQ trends which large flexible aircraft exhibit under various parameterizations of control laws and handling qualities are discussed. A summary of the assumptions and solution technique, a control law parameterization review, a discussion of ride sensitivity to handling qualities, and the RQ effects generated by implementing relaxed static stability configurations are included.

  13. Slew maneuvers of Spacecraft Control Laboratory Experiment (SCOLE)

    NASA Technical Reports Server (NTRS)

    Kakad, Yogendra P.

    1992-01-01

    This is the final report on the dynamics and control of slew maneuvers of the Spacecraft Control Laboratory Experiment (SCOLE) test facility. The report documents the basic dynamical equation derivations for an arbitrary large angle slew maneuver as well as the basic decentralized slew maneuver control algorithm. The set of dynamical equations incorporate rigid body slew maneuver and three dimensional vibrations of the complete assembly comprising the rigid shuttle, the flexible beam, and the reflector with an offset mass. The analysis also includes kinematic nonlinearities of the entire assembly during the maneuver and the dynamics of the interactions between the rigid shuttle and the flexible appendage. The equations are simplified and evaluated numerically to include the first ten flexible modes to yield a model for designing control systems to perform slew maneuvers. The control problem incorporates the nonlinear dynamical equations and is expressed in terms of a two point boundary value problem.

  14. Piloting Laboratory Quality System Management in Six Health Facilities in Nigeria

    PubMed Central

    Mbah, Henry; Ojo, Emmanuel; Ameh, James; Musuluma, Humphrey; Negedu-Momoh, Olubunmi Ruth; Jegede, Feyisayo; Ojo, Olufunmilayo; Uwakwe, Nkem; Ochei, Kingsley; Dada, Michael; Udah, Donald; Chiegil, Robert; Torpey, Kwasi

    2014-01-01

    Background Achieving accreditation in laboratories is a challenge in Nigeria like in most African countries. Nigeria adopted the World Health Organization Regional Office for Africa Stepwise Laboratory (Quality) Improvement Process Towards Accreditation (WHO/AFRO– SLIPTA) in 2010. We report on FHI360 effort and progress in piloting WHO-AFRO recognition and accreditation preparedness in six health facility laboratories in five different states of Nigeria. Method Laboratory assessments were conducted at baseline, follow up and exit using the WHO/AFRO– SLIPTA checklist. From the total percentage score obtained, the quality status of laboratories were classified using a zero to five star rating, based on the WHO/AFRO quality improvement stepwise approach. Major interventions include advocacy, capacity building, mentorship and quality improvement projects. Results At baseline audit, two of the laboratories attained 1- star while the remaining four were at 0- star. At follow up audit one lab was at 1- star, two at 3-star and three at 4-star. At exit audit, four labs were at 4- star, one at 3-star and one at 2-star rating. One laboratory dropped a ‘star’ at exit audit, while others consistently improved. The two weakest elements at baseline; internal audit (4%) and occurrence/incidence management (15%) improved significantly, with an exit score of 76% and 81% respectively. The elements facility and safety was the major strength across board throughout the audit exercise. Conclusion This effort resulted in measurable and positive impact on the laboratories. We recommend further improvement towards a formal international accreditation status and scale up of WHO/AFRO– SLIPTA implementation in Nigeria. PMID:25542022

  15. Participation in Performance-Evaluation Studies by U.S. Geological Survey National Water Quality Laboratory

    USGS Publications Warehouse

    Glodt, Stephen R.; Pirkey, Kimberly D.

    1998-01-01

    Performance-evaluation studies provide customers of the U.S. Geological Survey National Water Quality Laboratory (NWQL) with data needed to evaluate performance and to compare of select laboratories for analytical work. The NWQL participates in national and international performance-evaluation (PE) studies that consist of samples of water, sediment, and aquatic biological materials for the analysis of inorganic constituents, organic compounds, and radionuclides. This Fact Sheet provides a summary of PE study results from January 1993 through April 1997. It should be of particular interest to USGS customers and potential customers of the NWQL, water-quality specialists, cooperators, and agencies of the Federal Government.

  16. NIF Projects Controls and Information Systems Software Quality Assurance Plan

    SciTech Connect

    Fishler, B

    2011-03-18

    Quality achievement for the National Ignition Facility (NIF) and the National Ignition Campaign (NIC) is the responsibility of the NIF Projects line organization as described in the NIF and Photon Science Directorate Quality Assurance Plan (NIF QA Plan). This Software Quality Assurance Plan (SQAP) is subordinate to the NIF QA Plan and establishes quality assurance (QA) activities for the software subsystems within Controls and Information Systems (CIS). This SQAP implements an activity level software quality assurance plan for NIF Projects as required by the LLNL Institutional Software Quality Assurance Program (ISQAP). Planned QA activities help achieve, assess, and maintain appropriate quality of software developed and/or acquired for control systems, shot data systems, laser performance modeling systems, business applications, industrial control and safety systems, and information technology systems. The objective of this SQAP is to ensure that appropriate controls are developed and implemented for management planning, work execution, and quality assessment of the CIS organization's software activities. The CIS line organization places special QA emphasis on rigorous configuration control, change management, testing, and issue tracking to help achieve its quality goals.

  17. Teaching Quality Control with Chocolate Chip Cookies

    ERIC Educational Resources Information Center

    Baker, Ardith

    2014-01-01

    Chocolate chip cookies are used to illustrate the importance and effectiveness of control charts in Statistical Process Control. By counting the number of chocolate chips, creating the spreadsheet, calculating the control limits and graphing the control charts, the student becomes actively engaged in the learning process. In addition, examining…

  18. 10 CFR 26.167 - Quality assurance and quality control.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... tests. (1) Requirements for performing creatinine tests: (i) The creatinine concentration must be measured to one decimal place on both the initial and the confirmatory creatinine tests; (ii) The initial creatinine test must have a calibrator at 2 mg/dL; (iii) The initial creatinine test must have a control...

  19. 10 CFR 26.167 - Quality assurance and quality control.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... tests. (1) Requirements for performing creatinine tests: (i) The creatinine concentration must be measured to one decimal place on both the initial and the confirmatory creatinine tests; (ii) The initial creatinine test must have a calibrator at 2 mg/dL; (iii) The initial creatinine test must have a control...

  20. 10 CFR 26.167 - Quality assurance and quality control.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... tests. (1) Requirements for performing creatinine tests: (i) The creatinine concentration must be measured to one decimal place on both the initial and the confirmatory creatinine tests; (ii) The initial creatinine test must have a calibrator at 2 mg/dL; (iii) The initial creatinine test must have a control...

  1. Annular Momentum Control Device (AMCD). Volume 1: Laboratory model development

    NASA Technical Reports Server (NTRS)

    1975-01-01

    The annular momentum control device (AMCD) a thin hoop-like wheel with neither shaft nor spokes is described. The wheel floats in a magnetic field and can be rotated by a segmented motor. Potential advantages of such a wheel are low weight, configuration flexibility, a wheel that stiffens with increased speed, vibration isolation, and increased reliability. The analysis, design, fabrication, and testing is described of the laboratory model of the AMCD.

  2. 40 CFR 81.122 - Mississippi Delta Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...2013-07-01 2013-07-01 false Mississippi Delta Intrastate Air Quality Control Region...Control Regions § 81.122 Mississippi Delta Intrastate Air Quality Control Region. The Mississippi Delta Intrastate Air Quality Control...

  3. 40 CFR 81.122 - Mississippi Delta Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...2012-07-01 2012-07-01 false Mississippi Delta Intrastate Air Quality Control Region...Control Regions § 81.122 Mississippi Delta Intrastate Air Quality Control Region. The Mississippi Delta Intrastate Air Quality Control...

  4. 40 CFR 81.122 - Mississippi Delta Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...2014-07-01 2014-07-01 false Mississippi Delta Intrastate Air Quality Control Region...Control Regions § 81.122 Mississippi Delta Intrastate Air Quality Control Region. The Mississippi Delta Intrastate Air Quality Control...

  5. 40 CFR 81.17 - Metropolitan Los Angeles Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...2010-07-01 2010-07-01 false Metropolitan Los Angeles Air Quality Control Region. 81...Control Regions § 81.17 Metropolitan Los Angeles Air Quality Control Region. The Metropolitan Los Angeles Air Quality Control Region...

  6. 40 CFR 81.17 - Metropolitan Los Angeles Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...2011-07-01 2011-07-01 false Metropolitan Los Angeles Air Quality Control Region. 81...Control Regions § 81.17 Metropolitan Los Angeles Air Quality Control Region. The Metropolitan Los Angeles Air Quality Control Region...

  7. 40 CFR 81.167 - Southeast Desert Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...2013-07-01 2013-07-01 false Southeast Desert Intrastate Air Quality Control Region...Control Regions § 81.167 Southeast Desert Intrastate Air Quality Control Region. The Southeast Desert Intrastate Air Quality Control...

  8. 40 CFR 81.167 - Southeast Desert Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...2014-07-01 2014-07-01 false Southeast Desert Intrastate Air Quality Control Region...Control Regions § 81.167 Southeast Desert Intrastate Air Quality Control Region. The Southeast Desert Intrastate Air Quality Control...

  9. 40 CFR 81.167 - Southeast Desert Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...2011-07-01 2011-07-01 false Southeast Desert Intrastate Air Quality Control Region...Control Regions § 81.167 Southeast Desert Intrastate Air Quality Control Region. The Southeast Desert Intrastate Air Quality Control...

  10. 40 CFR 81.167 - Southeast Desert Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...2012-07-01 2012-07-01 false Southeast Desert Intrastate Air Quality Control Region...Control Regions § 81.167 Southeast Desert Intrastate Air Quality Control Region. The Southeast Desert Intrastate Air Quality Control...

  11. 40 CFR 81.167 - Southeast Desert Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...2010-07-01 2010-07-01 false Southeast Desert Intrastate Air Quality Control Region...Control Regions § 81.167 Southeast Desert Intrastate Air Quality Control Region. The Southeast Desert Intrastate Air Quality Control...

  12. 40 CFR 81.122 - Mississippi Delta Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...2010-07-01 2010-07-01 false Mississippi Delta Intrastate Air Quality Control Region...Control Regions § 81.122 Mississippi Delta Intrastate Air Quality Control Region. The Mississippi Delta Intrastate Air Quality Control...

  13. 40 CFR 81.122 - Mississippi Delta Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...2011-07-01 2011-07-01 false Mississippi Delta Intrastate Air Quality Control Region...Control Regions § 81.122 Mississippi Delta Intrastate Air Quality Control Region. The Mississippi Delta Intrastate Air Quality Control...

  14. Environmental control: operating room air quality.

    PubMed

    Bartley, J M

    1993-01-01

    1. OR staff members should familiarize themselves with basic air handling system terminology to better manage their own environment (eg, HVAC, air changes, air balancing, HEPA filtration). A working relationship with building engineers is an important skill for the OR nurse. 2. Knowledge of the standards on which air quality in the OR is based should assist in the process of planning for improved design--as well as in monitoring existing air quality. 3. Current standards balance energy savings with air changes and high levels of filtration to achieve optimum outcomes. Recommendations from design and engineering authorities (even for implant surgery) are based on average air changes and HEPA filtration, not laminar air flow. 4. The daily, operational role of the OR staff in maintaining high air quality includes managing traffic, using low-lint barrier materials, monitoring air quality indicators, and investigating unusual variances with the engineering staff for appropriate follow-up (eg, filter changes). PMID:8212097

  15. A diagnostic procedure for multivariate quality control 

    E-print Network

    Keserla, Adhinarayan A.

    1993-01-01

    There are many instances in which the quality of a product or stability of a process is determined by several variables. Most often there exist correlations among the variables monitored. In such situations one wishes to take advantage...

  16. Vibration control for precision manufacturing at Sandia National Laboratories

    SciTech Connect

    Hinnerichs, T.; Martinez, D.

    1995-04-01

    Sandia National Laboratories performs R and D in structural dynamics and vibration suppression for precision applications in weapon systems, space, underwater, transportation and civil structures. Over the last decade these efforts have expanded into the areas of active vibration control and ``smart`` structures and material systems. In addition, Sandia has focused major resources towards technology to support weapon product development and agile manufacturing capability for defense and industrial applications. This paper will briefly describe the structural dynamics modeling and verification process currently in place at Sandia that supports vibration control and some specific applications of these techniques to manufacturing in the areas of lithography, machine tools and flexible robotics.

  17. Comparison of Laboratory and Field Remote Sensing Methods to Measure Forage Quality

    PubMed Central

    Guo, Xulin; Wilmshurst, John F.; Li, Zhaoqin

    2010-01-01

    Recent research in range ecology has emphasized the importance of forage quality as a key indicator of rangeland condition. However, we lack tools to evaluate forage quality at scales appropriate for management. Using canopy reflectance data to measure forage quality has been conducted at both laboratory and field levels separately, but little work has been conducted to evaluate these methods simultaneously. The objective of this study is to find a reliable way of assessing grassland quality through measuring forage chemistry with reflectance. We studied a mixed grass ecosystem in Grasslands National Park of Canada and surrounding pastures, located in southern Saskatchewan. Spectral reflectance was collected at both in-situ field level and in the laboratory. Vegetation samples were collected at each site, sorted into the green grass portion, and then sent to a chemical company for measuring forage quality variables, including protein, lignin, ash, moisture at 135 °C, Neutral Detergent Fiber (NDF), Acid Detergent Fiber (ADF), Total Digestible, Digestible Energy, Net Energy for Lactation, Net Energy for Maintenance, and Net Energy for Gain. Reflectance data were processed with the first derivative transformation and continuum removal method. Correlation analysis was conducted on spectral and forage quality variables. A regression model was further built to investigate the possibility of using canopy spectral measurements to predict the grassland quality. Results indicated that field level prediction of protein of mixed grass species was possible (r2 = 0.63). However, the relationship between canopy reflectance and the other forage quality variables was not strong. PMID:20948940

  18. Quality management at Argonne National Laboratory: Status, accomplishments, and lessons learned

    SciTech Connect

    1995-06-01

    In April 1992, Argonne National Laboratory (ANL) launched the implementation of quality management (QM) as an initiative of the Laboratory Director. The goal of the program is to seek ways of improving Laboratory performance and effectiveness by drawing from the realm of experiences in the global total quality management movement. The Argonne QM initiative began with fact finding and formulating a strategy for implementation; the emphasis is that the underlying principles of QM should be an integral part of how the Laboratory is managed and operated. A primary theme that has guided the Argonne QM initiative is to consider only those practices that offer the potential for real improvement, make sense, fit the culture, and would be credible to the broad population. In October 1993, the Laboratory began to pilot a targeted set of QM activities selected to produce outcomes important to the Laboratory--strengthening the customer focus, improving work processes, enhancing employee involvement and satisfaction, and institutionalizing QM. This report describes the results of the just-concluded QM development and demonstration phase in terms of detailed strategies, accomplishments, and lessons learned. These results are offered as evidence to support the conclusion that the Argonne QM initiative has achieved value-added results and credibility and is well positioned to support future deployment across the entire Laboratory as an integrated management initiative. Recommendations for follow-on actions to implement future deployment are provided separately.

  19. Requirements for quality control of analytical data for the Environmental Restoration Program

    SciTech Connect

    Engels, J.

    1992-12-01

    The Environmental Restoration (ER) Program was established for the investigation and remediation of inactive US Department of Energy (DOE) sites and facilities that have been declared surplus in terms of their previous uses. The purpose of this document is to Specify ER requirements for quality control (QC) of analytical data. Activities throughout all phases of the investigation may affect the quality of the final data product, thus are subject to control specifications. Laboratory control is emphasized in this document, and field concerns will be addressed in a companion document Energy Systems, in its role of technical coordinator and at the request of DOE-OR, extends the application of these requirements to all participants in ER activities. Because every instance and concern may not be addressed in this document, participants are encouraged to discuss any questions with the ER Quality Assurance (QA) Office, the Analytical Environmental Support Group (AESG), or the Analytical Project Office (APO).

  20. Real time quality control of meteorological data used in SRP's emergency response system

    SciTech Connect

    Pendergast, M.M.

    1980-05-01

    The Savannah River Laboratory's WIND minicomputer system allows quick and accurate assessment of an accidental release at the Savannah River Plant using data from eight meteorological towers. The accuracy of the assessment is largely determined by the accuracy of the meteorological data; therefore quality control is important in an emergency response system. Real-time quality control of this data will be added to the WIND system to automatically identify inaccurate data. Currently, the system averages the measurements from the towers to minimize the influence of inaccurate data being used in calculations. The computer code used in the real-time quality control has been previously used to identify inaccurate measurements from the archived tower data.

  1. Web quality control for lectures: Supercourse and Amazon.com.

    PubMed

    Linkov, Faina; LaPorte, Ronald; Lovalekar, Mita; Dodani, Sunita

    2005-12-01

    Peer review has been at the corner stone of quality control of the biomedical journals in the past 300 years. With the emergency of the Internet, new models of quality control and peer review are emerging. However, such models are poorly investigated. We would argue that the popular system of quality control used in Amazon.com offers a way to ensure continuous quality improvement in the area of research communications on the Internet. Such system is providing an interesting alternative to the traditional peer review approaches used in the biomedical journals and challenges the traditional paradigms of scientific publishing. This idea is being explored in the context of Supercourse, a library of 2,350 prevention lectures, shared for free by faculty members from over 150 countries. Supercourse is successfully utilizing quality control approaches that are similar to Amazon.com model. Clearly, the existing approaches and emerging alternatives for quality control in scientific communications needs to be assessed scientifically. Rapid explosion of internet technologies could be leveraged to produce better, more cost effective systems for quality control in the biomedical publications and across all sciences. PMID:16342339

  2. 40 CFR 81.112 - Charleston Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Quality Control Regions § 81.112 Charleston Intrastate Air Quality Control Region. The Charleston Intrastate Air Quality Control Region (South Carolina) consists of the territorial area encompassed by the... Quality Control Region: Region 1. 81.107Greenwood Intrastate Air Quality Control Region: Region 2....

  3. 40 CFR 81.88 - Billings Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Quality Control Regions § 81.88 Billings Intrastate Air Quality Control Region. The Metropolitan Billings Intrastate Air Quality Control Region (Montana) has been renamed the Billings Intrastate Air Quality Control... to by Montana authorities as follows: Sec. 481.168Great Falls Intrastate Air Quality Control...

  4. 40 CFR 81.112 - Charleston Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Quality Control Regions § 81.112 Charleston Intrastate Air Quality Control Region. The Charleston Intrastate Air Quality Control Region (South Carolina) consists of the territorial area encompassed by the... Quality Control Region: Region 1. 81.107Greenwood Intrastate Air Quality Control Region: Region 2....

  5. 21 CFR 111.105 - What must quality control personnel do?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 2 2012-04-01 2012-04-01 false What must quality control personnel do? 111.105... for Quality Control § 111.105 What must quality control personnel do? Quality control personnel must... manufacturing record. To do so, quality control personnel must perform operations that include: (a) Approving...

  6. 40 CFR 81.88 - Billings Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Quality Control Regions § 81.88 Billings Intrastate Air Quality Control Region. The Metropolitan Billings Intrastate Air Quality Control Region (Montana) has been renamed the Billings Intrastate Air Quality Control... to by Montana authorities as follows: Sec. 481.168Great Falls Intrastate Air Quality Control...

  7. 40 CFR 81.88 - Billings Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Quality Control Regions § 81.88 Billings Intrastate Air Quality Control Region. The Metropolitan Billings Intrastate Air Quality Control Region (Montana) has been renamed the Billings Intrastate Air Quality Control... to by Montana authorities as follows: Sec. 481.168Great Falls Intrastate Air Quality Control...

  8. 40 CFR 81.112 - Charleston Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Quality Control Regions § 81.112 Charleston Intrastate Air Quality Control Region. The Charleston Intrastate Air Quality Control Region (South Carolina) consists of the territorial area encompassed by the... Quality Control Region: Region 1. 81.107Greenwood Intrastate Air Quality Control Region: Region 2....

  9. 40 CFR 81.88 - Billings Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Quality Control Regions § 81.88 Billings Intrastate Air Quality Control Region. The Metropolitan Billings Intrastate Air Quality Control Region (Montana) has been renamed the Billings Intrastate Air Quality Control... to by Montana authorities as follows: Sec. 481.168Great Falls Intrastate Air Quality Control...

  10. 40 CFR 81.112 - Charleston Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Quality Control Regions § 81.112 Charleston Intrastate Air Quality Control Region. The Charleston Intrastate Air Quality Control Region (South Carolina) consists of the territorial area encompassed by the... Quality Control Region: Region 1. 81.107Greenwood Intrastate Air Quality Control Region: Region 2....

  11. Soil Quality Assessment -- A Value Added Opportunity for Soil Testing Laboratories

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Soil-testing laboratories have an emerging opportunity to provide soil quality (SQ) assessment as a value-added service to clients interested in quantifying the sustainability of their agricultural practices. This presentation briefly reviews the evolution of SQ assessment and introduces four assess...

  12. 78 FR 29376 - Accreditation and Approval of Quality Custom Inspections & Laboratories, LLC, as a Commercial...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-20

    ...Notice is hereby given, pursuant to CBP regulations, that Quality Custom Inspections & Laboratories, LLC, has been approved to gauge and accredited to test petroleum and petroleum products, organic chemicals and vegetable oils for customs purposes for the next three years as of September 18,...

  13. Use of Proficiency Testing as a Tool to Improve Quality in Microbiology Laboratories

    PubMed Central

    Stang, Heather L.; Anderson, Nancy L.

    2015-01-01

    Proficiency testing (PT) is a valuable tool for assessing laboratory performance and verifying the accuracy and reliability of test results. Participation is required by the Clinical Laboratory Improvement Amendments (CLIA) of 1988 for each of the microbiology subspecialties (bacteriology, mycobacteriology, mycology, parasitology, and virology), and the regulations include specific PT requirements for each subspecialty. To determine the use and perceived value of PT beyond meeting CLIA requirements, the Centers for Disease Control and Prevention funded a cooperative agreement with the Association of Public Health Laboratories to convene a series of focus groups to query laboratory professionals responsible for PT. The seven focus groups were comprised of 60 laboratory professionals representing large and small clinical laboratories, microbiology subspecialties, and public health. While participants acknowledged the need to perform PT to meet regulatory requirements, many also cited benefits and challenges beyond regulatory compliance.

  14. Indoor air quality control for improving passenger health in subway platforms using an outdoor air quality dependent ventilation system

    E-print Network

    Indoor air quality control for improving passenger health in subway platforms using an outdoor air online 19 May 2015 Keywords: Ventilation control system Indoor air quality Indoor air pollution control Outdoor air quality Passenger health promotion Ventilation energy a b s t r a c t Indoor air quality (IAQ

  15. Mesh quality control for multiply-refined tetrahedral grids

    NASA Technical Reports Server (NTRS)

    Biswas, Rupak; Strawn, Roger

    1994-01-01

    A new algorithm for controlling the quality of multiply-refined tetrahedral meshes is presented in this paper. The basic dynamic mesh adaption procedure allows localized grid refinement and coarsening to efficiently capture aerodynamic flow features in computational fluid dynamics problems; however, repeated application of the procedure may significantly deteriorate the quality of the mesh. Results presented show the effectiveness of this mesh quality algorithm and its potential in the area of helicopter aerodynamics and acoustics.

  16. Federal, State, and Local Water Quality Control

    E-print Network

    Radcliffe, David

    and non-point pollution is causing many water bodies to fail state water quality standards. Since in many cases these polluted water bodies are vital to communi- ties as both a source of drinking water-5-23.1. These two laws are intended to protect water bodies from excessive point and non-point pollution

  17. Data Quality Objectives Supporting Radiological Air Emissions Monitoring for the Marine Sciences Laboratory, Sequim Site

    SciTech Connect

    Barnett, J. M.; Meier, Kirsten M.; Snyder, Sandra F.; Antonio, Ernest J.; Fritz, Brad G.; Poston, Theodore M.

    2012-12-27

    This document of Data Quality Objectives (DQOs) was prepared based on the U.S. Environmental Protection Agency (EPA) Guidance on Systematic Planning Using the Data Quality Objectives Process, EPA, QA/G4, 2/2006 (EPA 2006), as well as several other published DQOs. The intent of this report is to determine the necessary steps required to ensure that radioactive emissions to the air from the Marine Sciences Laboratory (MSL) headquartered at the Pacific Northwest National Laboratory’s Sequim Marine Research Operations (Sequim Site) on Washington State’s Olympic Peninsula are managed in accordance with regulatory requirements and best practices. The Sequim Site was transitioned in October 2012 from private operation under Battelle Memorial Institute to an exclusive use contract with the U.S. Department of Energy, Office of Science, Pacific Northwest Site Office.

  18. 78 FR 33441 - Importer of Controlled Substances; Notice of Registration; Caraco Pharmaceutical Laboratories, LTD

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-04

    ..., 78 FR 12101, Caraco Pharmaceutical Laboratories, Ltd., 270 Prospect Plains Road, Cranbury, New Jersey... Enforcement Administration Importer of Controlled Substances; Notice of Registration; Caraco Pharmaceutical... registration of Caraco Pharmaceutical Laboratories, Ltd., to import the basic class of controlled substance...

  19. Lessons Learned from Implementing a Wet Laboratory Molecular Training Workshop for Beach Water Quality Monitoring

    PubMed Central

    Verhougstraete, Marc Paul; Brothers, Sydney; Litaker, Wayne; Blackwood, A. Denene; Noble, Rachel

    2015-01-01

    Rapid molecular testing methods are poised to replace many of the conventional, culture-based tests currently used in fields such as water quality and food science. Rapid qPCR methods have the benefit of being faster than conventional methods and provide a means to more accurately protect public health. However, many scientists and technicians in water and food quality microbiology laboratories have limited experience using these molecular tests. To ensure that practitioners can use and implement qPCR techniques successfully, we developed a week long workshop to provide hands-on training and exposure to rapid molecular methods for water quality management. This workshop trained academic professors, government employees, private industry representatives, and graduate students in rapid qPCR methods for monitoring recreational water quality. Attendees were immersed in these new methods with hands-on laboratory sessions, lectures, and one-on-one training. Upon completion, the attendees gained sufficient knowledge and practice to teach and share these new molecular techniques with colleagues at their respective laboratories. Key findings from this workshop demonstrated: 1) participants with no prior experience could be effectively trained to conduct highly repeatable qPCR analysis in one week; 2) participants with different desirable outcomes required exposure to a range of different platforms and sample processing approaches; and 3) the collaborative interaction amongst newly trained practitioners, workshop leaders, and members of the water quality community helped foster a cohesive cohort of individuals which can advocate powerful cohort for proper implementation of molecular methods. PMID:25822486

  20. Lessons learned from implementing a wet laboratory molecular training workshop for beach water quality monitoring.

    PubMed

    Verhougstraete, Marc Paul; Brothers, Sydney; Litaker, Wayne; Blackwood, A Denene; Noble, Rachel

    2015-01-01

    Rapid molecular testing methods are poised to replace many of the conventional, culture-based tests currently used in fields such as water quality and food science. Rapid qPCR methods have the benefit of being faster than conventional methods and provide a means to more accurately protect public health. However, many scientists and technicians in water and food quality microbiology laboratories have limited experience using these molecular tests. To ensure that practitioners can use and implement qPCR techniques successfully, we developed a week long workshop to provide hands-on training and exposure to rapid molecular methods for water quality management. This workshop trained academic professors, government employees, private industry representatives, and graduate students in rapid qPCR methods for monitoring recreational water quality. Attendees were immersed in these new methods with hands-on laboratory sessions, lectures, and one-on-one training. Upon completion, the attendees gained sufficient knowledge and practice to teach and share these new molecular techniques with colleagues at their respective laboratories. Key findings from this workshop demonstrated: 1) participants with no prior experience could be effectively trained to conduct highly repeatable qPCR analysis in one week; 2) participants with different desirable outcomes required exposure to a range of different platforms and sample processing approaches; and 3) the collaborative interaction amongst newly trained practitioners, workshop leaders, and members of the water quality community helped foster a cohesive cohort of individuals which can advocate powerful cohort for proper implementation of molecular methods. PMID:25822486

  1. 21 CFR 640.56 - Quality control test for potency.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 7 2011-04-01 2010-04-01 true Quality control test for potency. 640.56 Section 640.56 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS ADDITIONAL STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS Cryoprecipitate § 640.56 Quality...

  2. 21 CFR 640.56 - Quality control test for potency.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Quality control test for potency. 640.56 Section 640.56 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS ADDITIONAL STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS Cryoprecipitate § 640.56 Quality...

  3. 115. QUALITY CONTROL BOARD FOR MAINTENANCE AND INSPECTION AT SOUTH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    115. QUALITY CONTROL BOARD FOR MAINTENANCE AND INSPECTION AT SOUTH SIDE OF MECHANICAL AND ELECTRICAL ROOM (110), LSB (BLDG. 770), FACING WEST ON EXTERIOR WALL OF QUALITY ASSURANCE ROOM (106A) - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 West, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

  4. Academic Quality Control in Nigerian Universities: Exploring Lecturers' Perceptions

    ERIC Educational Resources Information Center

    Obiekezie, E. O.; Ejemot-Nwadiaro, R. I.; Essien, M. I.; Timothy, A. Essien

    2014-01-01

    The level of job performance, international comparability and competitiveness of Nigerian university graduates are burning issues. Consequently, the academic quality of Nigerian universities has come under severe criticism. Since university lecturers are key players in quality control in universities, this study explored their perceptions of…

  5. Supplemental Control for Aircraft Riding Qualities

    NASA Technical Reports Server (NTRS)

    Williams, Rolanda S.; Ashokkumar, C. R.; Homaifar, Abdollah

    1997-01-01

    The concept of preview control has been applied and proven to be successful in the automotive vehicle. These same concepts are now applied to an aircraft under the assumption that exogenous inputs (wind gust, turbulence, etc. ) can be measured. A supplemental control law for surface deflection is designed to compensate for the loss in performance in the presence of atmospheric disturbances. Fuzzy logic control is employed to handle the nonlinear, time varying characteristics of the disturbance. A methodology to tune the outer loop control parameters is presented.

  6. 42 CFR 84.41 - Quality control plans; contents.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...inspection or verification of specification, and in-process...sufficient to ensure control of product quality through the manufacturing...procedure shall include a list of the characteristics to...immediately hazardous to life or health for...

  7. 42 CFR 84.41 - Quality control plans; contents.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...inspection or verification of specification, and in-process...sufficient to ensure control of product quality through the manufacturing...procedure shall include a list of the characteristics to...immediately hazardous to life or health for...

  8. 42 CFR 84.41 - Quality control plans; contents.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...inspection or verification of specification, and in-process...sufficient to ensure control of product quality through the manufacturing...procedure shall include a list of the characteristics to...immediately hazardous to life or health for...

  9. 42 CFR 84.41 - Quality control plans; contents.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...inspection or verification of specification, and in-process...sufficient to ensure control of product quality through the manufacturing...procedure shall include a list of the characteristics to...immediately hazardous to life or health for...

  10. 42 CFR 84.41 - Quality control plans; contents.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...inspection or verification of specification, and in-process...sufficient to ensure control of product quality through the manufacturing...procedure shall include a list of the characteristics to...immediately hazardous to life or health for...

  11. Exploring former interaction qualities for tomorrow's control room design

    E-print Network

    Reiterer, Harald

    may therefore not pro- vide an adequate mental model for the operator (Wickens 2004). Hence, a crucial former interaction qualities for tomorrow's control room design 2 awareness (Wickens 2004) which both

  12. A quality control program for waste disposal vault closure

    SciTech Connect

    Benny, H.L.

    1994-07-01

    This paper provides a review of the quality control program employed for closure for a radioactive waste disposal vault at Hanford Washington. The major elements of the program are discussed, as well as the testing results and lessons learned.

  13. Quality improvement and control based on defect reduction

    E-print Network

    Dai, Qi, M. Eng. Massachusetts Institute of Technology

    2010-01-01

    This thesis addresses the quality improvement in a printing process at a food packaging company now experiencing hundreds of printing defects. Methodologies of Define, Measure, Analyze, Improve, and Control (DMAIC), and ...

  14. Protein quality control in the mammalian endoplasmic reticulum

    E-print Network

    Klemm, Elizabeth J. (Elizabeth Joanna)

    2011-01-01

    Quality control is an important part of protein biogenesis. Aberrant proteins must be destroyed before they aggregate and cause deleterious effects. Failure to do so can result in cell death or malfunction and, ultimately, ...

  15. 7 CFR 58.335 - Quality control tests.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...Operating Procedures § 58.335 Quality control tests. All milk, cream and related products are subject to inspection for...correcting deficiencies in processing and manufacturing. Routine analysis shall be made on raw materials and finished products to...

  16. 7 CFR 58.335 - Quality control tests.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...Operating Procedures § 58.335 Quality control tests. All milk, cream and related products are subject to inspection for...correcting deficiencies in processing and manufacturing. Routine analysis shall be made on raw materials and finished products to...

  17. Internal-control weaknesses at Department of Energy research laboratories

    SciTech Connect

    Not Available

    1982-12-15

    Two requests were made by Chairman, Permanent Subcommittee on Investigations, Senate Committee on Governmental Affairs, that GAO review the vulnerability of selected Department of Energy (DOE) research facilities to fraud, waste, and abuse. The review examined internal controls over payroll, procurement, and property management at six government-owned, contractor-operated (GOCO) research laboratories (Sandia, Hanford, Argonne, Oak Ridge, Fermi, and Brookhaven) and four government-owned, government-operated energy technology centers (Bartlesville, Laramie, Morgantown, and Pittsburgh). In fiscal 1982, DOE budgeted over $3 billion for its GOCO facilities and over $230 million for its energy technology centers. GAO noted specific problems at a number of the laboratories in each of the areas covered. In many instances, DOE has acknowledged the problems and corrective action is underway or is planned.

  18. Software quality assurance and software safety in the Biomed Control System

    SciTech Connect

    Singh, R.P.; Chu, W.T.; Ludewigt, B.A.; Marks, K.M.; Nyman, M.A.; Renner, T.R.; Stradtner, R.

    1989-10-31

    The Biomed Control System is a hardware/software system used for the delivery, measurement and monitoring of heavy-ion beams in the patient treatment and biology experiment rooms in the Bevalac at the Lawrence Berkeley Laboratory (LBL). This paper describes some aspects of this system including historical background philosophy, configuration management, hardware features that facilitate software testing, software testing procedures, the release of new software quality assurance, safety and operator monitoring. 3 refs.

  19. The making of a successful seminar: Pacific Northwest Laboratory`s {open_quotes}Quest for Quality{close_quotes}

    SciTech Connect

    Lumetta, C.C.; Downs, S.L.; Parnell, K.A.; Allen, R.E.

    1994-10-01

    Five contractors located on or near the Hanford Site in southeastern Washington State support technical communications staffs, all trying to meet the needs of one primary customer the U.S. Department of Energy. Historically, these staffs have maintained different processes and standards with regard to document production, and little interaction or information-sharing has occurred. To begin remedying that situation, the communications staff of Pacific Northwest Laboratory, a multiprogram national laboratory located in Richland, Wash., planned and hosted a one-day {open_quotes}Quest for Quality{close_quotes} seminar. The seminar was the first of its kind to comprise technical communications professionals from all the local DOE prime contractors, including technical editors and writers, publications assistants, text processors, and document production staff. The goals of the seminar were to identify ways to improve the quality of Hanford`s communication products and processes, to strengthen ties among technical communications staffs, and to open the lines of communication for future collaborative efforts. An eight-person committee selected topics, arranged facilities, recruited speakers, coordinated activities, hosted the seminar, and prepared proceedings.

  20. 78 FR 44954 - Clinical Laboratory Improvement Advisory Committee (CLIAC)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-25

    ... HUMAN SERVICES Centers for Disease Control and Prevention Clinical Laboratory Improvement Advisory... guidance pertain to general issues related to improvement in clinical laboratory quality and laboratory..., equity, and patient-centeredness of laboratory services; revisions to the standards under which...

  1. Quality Assurance and Quality Control Practices For Rehabilitation of Sewer and Water Mains

    EPA Science Inventory

    As part of the US Environmental Protection Agency (EPA)’s Aging Water Infrastructure Research Program, several areas of research are being pursued including a review of quality assurance and quality control (QA/QC) practices and acceptance testing during the installation of rehab...

  2. Quality Assurance and Quality Control Practices for Rehabilitation of Sewer and Water Mains

    EPA Science Inventory

    As part of the US Environmental Protection Agency (EPA)’s Aging Water Infrastructure Research Program, several areas of research are being pursued, including a review of quality assurance and quality control (QA/QC) practices and acceptance testing during the installation of reha...

  3. COMMUNITY MULTISCALE AIR QUALITY ( CMAQ ) MODEL - QUALITY ASSURANCE AND VERSION CONTROL

    EPA Science Inventory

    This presentation will be given to the EPA Exposure Modeling Workgroup on January 24, 2006. The quality assurance and version control procedures for the Community Multiscale Air Quality (CMAQ) Model are presented. A brief background of CMAQ is given, then issues related to qual...

  4. HANDBOOK: QUALITY ASSURANCE/QUALITY CONTROL (QA/QC) PROCEDURES FOR HAZARDOUS WASTE INCINERATION

    EPA Science Inventory

    Resource Conservation and Recovery Act regulations for hazardous waste incineration require trial burns by permit applicants. uality Assurance Project Plan (QAPjP) must accompany a trial burn plan with appropriate quality assurance/quality control procedures. uidance on the prepa...

  5. Development and Testing of a Nuclear Quality Assurance/Quality Control Technician Curriculum. Final Report.

    ERIC Educational Resources Information Center

    Espy, John; And Others

    A project was conducted to field test selected first- and second-year courses in a postsecondary nuclear quality assurance/quality control (QA/QC) technician curriculum and to develop the teaching/learning modules for seven technical specialty courses remaining in the QA/QC technician curriculum. The field testing phase of the project involved the…

  6. The 5th Annual NASA Spacecraft Control Laboratory Experiment (SCOLE) Workshop, part 2

    NASA Technical Reports Server (NTRS)

    Taylor, Lawrence W., Jr. (compiler)

    1990-01-01

    A collection of papers from the workshop are presented. The topics addressed include: the modeling, systems identification, and control synthesis for the Spacecraft Control Laboratory Experiment (SCOLE) configuration.

  7. 42 CFR 84.43 - Quality control records; review by the Institute; revocation of approval.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 1 2011-10-01 2011-10-01 false Quality control records; review by the Institute; revocation... APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Quality Control § 84.43 Quality control records; review by the Institute;...

  8. 40 CFR 81.274 - Mountain Counties Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...2014-07-01 2014-07-01 false Mountain Counties Intrastate Air Quality Control...Quality Control Regions § 81.274 Mountain Counties Intrastate Air Quality Control Region. The Mountain Counties Intrastate Air...

  9. 40 CFR 81.153 - Western Mountain Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...2013-07-01 2013-07-01 false Western Mountain Intrastate Air Quality Control Region...Control Regions § 81.153 Western Mountain Intrastate Air Quality Control Region. The Western Mountain Intrastate Air Quality...

  10. 40 CFR 81.274 - Mountain Counties Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...2011-07-01 2011-07-01 false Mountain Counties Intrastate Air Quality Control...Quality Control Regions § 81.274 Mountain Counties Intrastate Air Quality Control Region. The Mountain Counties Intrastate Air...

  11. 40 CFR 81.147 - Eastern Mountain Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...2010-07-01 2010-07-01 false Eastern Mountain Intrastate Air Quality Control Region...Control Regions § 81.147 Eastern Mountain Intrastate Air Quality Control Region. The Eastern Mountain Intrastate Air Quality...

  12. 40 CFR 81.153 - Western Mountain Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...2014-07-01 2014-07-01 false Western Mountain Intrastate Air Quality Control Region...Control Regions § 81.153 Western Mountain Intrastate Air Quality Control Region. The Western Mountain Intrastate Air Quality...

  13. 40 CFR 81.153 - Western Mountain Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...2011-07-01 2011-07-01 false Western Mountain Intrastate Air Quality Control Region...Control Regions § 81.153 Western Mountain Intrastate Air Quality Control Region. The Western Mountain Intrastate Air Quality...

  14. 40 CFR 81.147 - Eastern Mountain Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...2011-07-01 2011-07-01 false Eastern Mountain Intrastate Air Quality Control Region...Control Regions § 81.147 Eastern Mountain Intrastate Air Quality Control Region. The Eastern Mountain Intrastate Air Quality...

  15. 40 CFR 81.153 - Western Mountain Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...2012-07-01 2012-07-01 false Western Mountain Intrastate Air Quality Control Region...Control Regions § 81.153 Western Mountain Intrastate Air Quality Control Region. The Western Mountain Intrastate Air Quality...

  16. 40 CFR 81.147 - Eastern Mountain Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...2012-07-01 2012-07-01 false Eastern Mountain Intrastate Air Quality Control Region...Control Regions § 81.147 Eastern Mountain Intrastate Air Quality Control Region. The Eastern Mountain Intrastate Air Quality...

  17. 40 CFR 81.274 - Mountain Counties Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...2013-07-01 2013-07-01 false Mountain Counties Intrastate Air Quality Control...Quality Control Regions § 81.274 Mountain Counties Intrastate Air Quality Control Region. The Mountain Counties Intrastate Air...

  18. 40 CFR 81.274 - Mountain Counties Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...2010-07-01 2010-07-01 false Mountain Counties Intrastate Air Quality Control...Quality Control Regions § 81.274 Mountain Counties Intrastate Air Quality Control Region. The Mountain Counties Intrastate Air...

  19. 40 CFR 81.147 - Eastern Mountain Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...2014-07-01 2014-07-01 false Eastern Mountain Intrastate Air Quality Control Region...Control Regions § 81.147 Eastern Mountain Intrastate Air Quality Control Region. The Eastern Mountain Intrastate Air Quality...

  20. 40 CFR 81.147 - Eastern Mountain Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...2013-07-01 2013-07-01 false Eastern Mountain Intrastate Air Quality Control Region...Control Regions § 81.147 Eastern Mountain Intrastate Air Quality Control Region. The Eastern Mountain Intrastate Air Quality...

  1. 40 CFR 81.153 - Western Mountain Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...2010-07-01 2010-07-01 false Western Mountain Intrastate Air Quality Control Region...Control Regions § 81.153 Western Mountain Intrastate Air Quality Control Region. The Western Mountain Intrastate Air Quality...

  2. 40 CFR 81.274 - Mountain Counties Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...2012-07-01 2012-07-01 false Mountain Counties Intrastate Air Quality Control...Quality Control Regions § 81.274 Mountain Counties Intrastate Air Quality Control Region. The Mountain Counties Intrastate Air...

  3. 40 CFR 81.191 - Appalachian Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...2014-07-01 false Appalachian Intrastate Air Quality Control Region. 81.191 Section...of Air Quality Control Regions § 81.191 Appalachian Intrastate Air Quality Control Region. The Appalachian Intrastate Air...

  4. 40 CFR 81.191 - Appalachian Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...2011-07-01 false Appalachian Intrastate Air Quality Control Region. 81.191 Section...of Air Quality Control Regions § 81.191 Appalachian Intrastate Air Quality Control Region. The Appalachian Intrastate Air...

  5. 40 CFR 81.191 - Appalachian Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...2013-07-01 false Appalachian Intrastate Air Quality Control Region. 81.191 Section...of Air Quality Control Regions § 81.191 Appalachian Intrastate Air Quality Control Region. The Appalachian Intrastate Air...

  6. 40 CFR 81.191 - Appalachian Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...2012-07-01 false Appalachian Intrastate Air Quality Control Region. 81.191 Section...of Air Quality Control Regions § 81.191 Appalachian Intrastate Air Quality Control Region. The Appalachian Intrastate Air...

  7. 40 CFR 81.191 - Appalachian Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...2010-07-01 false Appalachian Intrastate Air Quality Control Region. 81.191 Section...of Air Quality Control Regions § 81.191 Appalachian Intrastate Air Quality Control Region. The Appalachian Intrastate Air...

  8. 40 CFR 81.21 - San Francisco Bay Area Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 2010-07-01 false San Francisco Bay Area Intrastate Air Quality Control Region...Control Regions § 81.21 San Francisco Bay Area Intrastate Air Quality Control Region. The San Francisco Bay Area Intrastate Air Quality...

  9. 40 CFR 81.104 - Central Pennsylvania Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 2011-07-01 false Central Pennsylvania Intrastate Air Quality Control Region...Control Regions § 81.104 Central Pennsylvania Intrastate Air Quality Control Region. The Central Pennsylvania Intrastate Air Quality...

  10. 40 CFR 81.104 - Central Pennsylvania Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 2012-07-01 false Central Pennsylvania Intrastate Air Quality Control Region...Control Regions § 81.104 Central Pennsylvania Intrastate Air Quality Control Region. The Central Pennsylvania Intrastate Air Quality...

  11. 40 CFR 81.23 - Southwest Pennsylvania Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...2011-07-01 false Southwest Pennsylvania Intrastate Air Quality Control Region...Control Regions § 81.23 Southwest Pennsylvania Intrastate Air Quality Control Region. The Southwest Pennsylvania Intrastate Air Quality...

  12. 40 CFR 81.104 - Central Pennsylvania Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 2013-07-01 false Central Pennsylvania Intrastate Air Quality Control Region...Control Regions § 81.104 Central Pennsylvania Intrastate Air Quality Control Region. The Central Pennsylvania Intrastate Air Quality...

  13. 40 CFR 81.104 - Central Pennsylvania Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 2014-07-01 false Central Pennsylvania Intrastate Air Quality Control Region...Control Regions § 81.104 Central Pennsylvania Intrastate Air Quality Control Region. The Central Pennsylvania Intrastate Air Quality...

  14. 40 CFR 81.23 - Southwest Pennsylvania Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...2014-07-01 false Southwest Pennsylvania Intrastate Air Quality Control Region...Control Regions § 81.23 Southwest Pennsylvania Intrastate Air Quality Control Region. The Southwest Pennsylvania Intrastate Air Quality...

  15. 40 CFR 81.23 - Southwest Pennsylvania Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...2010-07-01 false Southwest Pennsylvania Intrastate Air Quality Control Region...Control Regions § 81.23 Southwest Pennsylvania Intrastate Air Quality Control Region. The Southwest Pennsylvania Intrastate Air Quality...

  16. 40 CFR 81.23 - Southwest Pennsylvania Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...2013-07-01 false Southwest Pennsylvania Intrastate Air Quality Control Region...Control Regions § 81.23 Southwest Pennsylvania Intrastate Air Quality Control Region. The Southwest Pennsylvania Intrastate Air Quality...

  17. 40 CFR 81.23 - Southwest Pennsylvania Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...2012-07-01 false Southwest Pennsylvania Intrastate Air Quality Control Region...Control Regions § 81.23 Southwest Pennsylvania Intrastate Air Quality Control Region. The Southwest Pennsylvania Intrastate Air Quality...

  18. 75 FR 80066 - Quality Control Requirements for Direct Endorsement Lenders; Notice of Proposed Information...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-21

    ... URBAN DEVELOPMENT Quality Control Requirements for Direct Endorsement Lenders; Notice of Proposed.... This Notice also lists the following information: Title of Proposal: Quality Control Requirements for... lenders, since these institutions must also conduct quality control on all loans they originate...

  19. 78 FR 69103 - 30-Day Notice of Proposed Information Collection: Quality Control for Rental Assistance Subsidy...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-18

    ... URBAN DEVELOPMENT 30-Day Notice of Proposed Information Collection: Quality Control for Rental... Information Collection: Quality Control for Rental Assistance Subsidy Determinations. OMB Approval Number... Quality Control process involves selecting a nationally representative sample of assisted households...

  20. 40 CFR 81.14 - Metropolitan Chicago Interstate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 2013-07-01 false Metropolitan Chicago Interstate Air Quality Control Region...Control Regions § 81.14 Metropolitan Chicago Interstate Air Quality Control Region. The Metropolitan Chicago Interstate Air Quality...