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1

Analytical laboratory quality control charting  

SciTech Connect

In life the importance of setting goals is stressed. The desired end result must be envisioned to chart a path and determine indicators to provide feedback on the process. Quality does not happen by accident but is achieved through a constant process of setting goals, process development, monitoring process indicators, fine tuning the process, and achieving results. These goals are to be focused and clearly measurable. In industry and life the setting of goals with clear process indicators is often difficult because of the variable end result and scarcity of measurements. Laboratories are fortunate in that they have a plethora of measurements with known or desired end results (controls) to monitor the process and give instantaneous feedback on quality. A key quality tool used by the laboratory to monitor and evaluate the lab processes is control charting. When properly utilized Quality Control (QC) Charts allow labs to be proactive in addressing problems rather than reactive. Several methods are available for control charting and some are listed in the references/information sources. The content for this paper is based on the control-charting program utilized at the Department of Energy's Fernald site. This control-charting program has specific areas of emphasis, simple charts, trend analyses, and effective follow-up.

O'Bryan, Ervin F.

2001-06-11

2

Quality control validation in veterinary laboratories.  

PubMed

Quality control (QC) validation is used to determine: 1) whether statistical QC procedures are appropriate for detecting medically important errors; and 2) the equality of performance required by different laboratory tests. QC validation is well documented in the medical literature, but we are unaware of studies addressing its application, problems or unique differences in veterinary laboratories. We applied QC validation to automated hematology and biochemistry analyses in our laboratories, with goals of >/= 90% probability of error detection and quality requirements in the form of total allowable error were defined using regulatory criteria for human proficiency testing; these were later modified based on clinician and pathologist feedback. Initial QC goals were not met for 14 of 49 (28.6%) analyte-control combinations. Subsequent modifications in methodology, analytical quality requirements and technician training achieved QC goals for all but one analyte. For this analyte (platelet count, low control), nonstatistical QC procedures were emphasized. QC validation was beneficial for clarifying statistical QC performance, and for assessing the need and justification for changes in methods and personnel training. The validation exercise allowed simplification of QC rules, enabled machine flagging of abnormal results, and decreased time and expense associated with QC recording, analysis, problem-solving and reruns. QC validation is recommended for all veterinary laboratories as a useful tool in total quality management. PMID:12075513

Freeman, Kathleen P.; Gruenwaldt, Julie

1999-01-01

3

Laboratory Quality Control Based on Risk Management  

PubMed Central

Risk management is the systematic application of management policies, procedures, and practices to the tasks of analyzing, evaluating, controlling and monitoring risk (the effect of uncertainty on objectives). Clinical laboratories conduct a number of activities that could be considered risk management including verification of performance of new tests, troubleshooting instrument problems and responding to physician complaints. Development of a quality control plan for a laboratory test requires a process map of the testing process with consideration for weak steps in the preanalytic, analytic and postanalytic phases of testing where there is an increased probability of errors. Control processes that either prevent or improve the detection of errors can be implemented at these weak points in the testing process to enhance the overall quality of the test result. This manuscript is based on a presentation at the 2nd International Symposium on Point of Care Testing held at King Faisal Specialist Hospital in Riyadh, Saudi Arabia on October 12-13, 2010. Risk management principles will be reviewed and progress towards adopting a new Clinical and Laboratory Standards Institute Guideline for developing laboratory quality control plans based on risk management will be discussed.

Nichols, James H.

2011-01-01

4

How to Write a Laboratory Quality Control Manual (597).  

National Technical Information Service (NTIS)

This course will provide detailed instructions and practice in how to develop and write a laboratory quality control manual. Upon completion of the course, each participant will be able to identify the desirable elements of a laboratory quality control pr...

1978-01-01

5

7 CFR 58.523 - Laboratory and quality control tests.  

Code of Federal Regulations, 2010 CFR

...523 Laboratory and quality control tests. (a) Quality control tests shall...necessary to determine the shelf-life and stability of...satisfactory composition, shelf-life and stability. ...ingredient. For keeping quality tests...

2009-01-01

6

7 CFR 58.523 - Laboratory and quality control tests.  

Code of Federal Regulations, 2010 CFR

...523 Laboratory and quality control tests. (a) Quality control tests shall...necessary to determine the shelf-life and stability of...satisfactory composition, shelf-life and stability. ...ingredient. For keeping quality tests...

2010-01-01

7

7 CFR 58.523 - Laboratory and quality control tests.  

Code of Federal Regulations, 2013 CFR

...523 Laboratory and quality control tests. (a) Quality control tests shall...determine the shelf-life and stability of the...composition, shelf-life and stability. ...ingredient. For keeping quality tests...

2013-01-01

8

[Our experience with outside laboratory quality control].  

PubMed

The results from the national outside laboratory qualitative control of the clinical diagnostic laboratory investigations for the period September 1975 -- May 1977 were described. The following interlaboratory discrepancy was found on base of a systematic analysis of the data from the last two ring-like check-ups, November 1976 and May 1977, exressed by the variation coefficient (V.C. %); total protein, sodium, potassium and chlorides -- under 10%; cholesterol, urea and total fats -- between 10 and 20%; calcium, phosphorus, iron and creatinine -- over 20%. The highest per cent of admissible results are found with total protein -- to 85%; cholesterol -- to 70.38%; glucosa -- to 73.17%, urea -- to 69.23%, potassium -- to 59.46%, chlorides -- to 57.9%. With sodium, phosphorus, calcium, iron creatinine and uric acid the "admissibility" fluctuates about or under 50 per cent. The values of the qualitative-control indices discussed are comparable with the values obtained from them in the interlaboratory comparisons of other countries. PMID:494628

Dochev, D; Arakasheva, V; Nashkov, A; Tsachev, K

1979-01-01

9

Implementing self sustained quality control procedures in a clinical laboratory.  

PubMed

Introduction: Quality control is an essential component in every clinical laboratory which maintains the excellence of laboratory standards, supplementing to proper disease diagnosis, patient care and resulting in overall strengthening of health care system. Numerous quality control schemes are available, with combinations of procedures, most of which are tedious, time consuming and can be "too technical" whereas commercially available quality control materials can be expensive especially for laboratories in developing nations like Nepal. Here, we present a procedure performed at our centre with self prepared control serum and use of simple statistical tools for quality assurance. Methods: The pooled serum was prepared as per guidelines for preparation of stabilized liquid quality control serum from human sera. Internal Quality Assessment was performed on this sample, on a daily basis which included measurement of 12 routine biochemical parameters. The results were plotted on Levey-Jennings charts and analysed with quality control rules, for a period of one month. Results: The mean levels of biochemical analytes in self prepared control serum were within normal physiological range. This serum was evaluated every day along with patients' samples. The results obtained were plotted on control charts and analysed using common quality control rules to identify possible systematic and random errors. Immediate mitigation measures were taken and the dispatch of erroneous reports was avoided. Conclusions: In this study we try to highlight on a simple internal quality control procedure which can be performed by laboratories, with minimum technology, expenditure, and expertise and improve reliability and validity of the test reports. Keywords: Levey-Jennings charts; pooled sera; quality control; Westgard Rule. PMID:23591302

Khatri, Roshan; Kc, Sanjay; Shrestha, Prabodh; Sinha, J N

10

HANDBOOK FOR ANALYTICAL QUALITY CONTROL IN WATER AND WASTEWATER LABORATORIES  

EPA Science Inventory

This handbook is addressed to laboratory directors, leaders of field investigations, and other personnel who bear responsibility for water and wastewater data. Subject matter of the handbook is concerned primarily with quality control (QC) for chemical and biological tests and me...

11

Quality control for diagnostic oral microbiology laboratories in European countries  

PubMed Central

Participation in diagnostic microbiology internal and external quality control (QC) processes is good laboratory practice and an essential component of a quality management system. However, no QC scheme for diagnostic oral microbiology existed until 2009 when the Clinical Oral Microbiology (COMB) Network was created. At the European Oral Microbiology Workshop in 2008, 12 laboratories processing clinical oral microbiological samples were identified. All these were recruited to participate into the study and six laboratories from six European countries completed both the online survey and the first QC round. Three additional laboratories participated in the second round. Based on the survey, European oral microbiology laboratories process a significant (mean per laboratory 4,135) number of diagnostic samples from the oral cavity annually. A majority of the laboratories did not participate in any internal or external QC programme and nearly half of the laboratories did not have standard operating procedures for the tests they performed. In both QC rounds, there was a large variation in the results, interpretation and reporting of antibiotic susceptibility testing among the laboratories. In conclusion, the results of this study demonstrate the need for harmonisation of laboratory processing methods and interpretation of results for oral microbiology specimens. The QC rounds highlighted the value of external QC in evaluating the efficacy and safety of processes, materials and methods used in the laboratory. The use of standardised methods is also a prerequisite for multi-centre epidemiological studies that can provide important information on emerging microbes and trends in anti-microbial susceptibility for empirical prescribing in oro-facial infections.

Rautemaa-Richardson, Riina; der Reijden Wa, Wil A Van; Dahlen, Gunnar; Smith, Andrew J.

2011-01-01

12

Implementing comprehensive quality control in the andrology laboratory.  

PubMed

Comprehensive quality control procedures were integrated into the routine semen analysis workload of a large university-based andrology laboratory. Methods were chosen to match as far as possible those which have been used successfully for many years in disciplines such as clinical chemistry. Levey-Jennings and cusum charts were plotted in order to monitor the immunobead-binding test for antisperm antibodies and a video-taped control sample for computerized semen analysis. A cryopreserved semen control was also charted. Daily manual sperm counts were plotted against the corresponding computer-assisted semen analysis (CASA) value. Multiple readings of 30 slides were used to monitor morphology assessments. Monthly means for morphology were also calculated regularly. Coefficients of variation were calculated for all variables and were found to be more appropriate for some aspects, such as CASA, than for others, such as morphology, when difference from the previous reading of the same slide was found to be more useful. These integrated quality control procedures had a direct influence on the production of results from the laboratory. Together with a high standard of technician training, comprehensive routine quality control based on repeated analyses of control samples is an effective way of assuring the validity of semen analysis results. PMID:8567848

Clements, S; Cooke, I D; Barratt, C L

1995-08-01

13

A suite of RS/1 procedures for chemical laboratory statistical quality control and Shewhart control charting  

SciTech Connect

A suite of RS/1 procedures for Shewhart control charting in chemical laboratories is described. The suite uses the RS series product QCA (Quality Control Analysis) for chart construction and analysis. The suite prompts users for data in a user friendly fashion and adds the data to or creates the control charts. All activities are time stamped. Facilities for generating monthly or contiguous time segment summary charts are included. The suite is currently in use at Westinghouse Savannah River Company.

Shanahan, K.L.

1990-09-01

14

Introducing Quality Control in the Chemistry Teaching Laboratory Using Control Charts  

ERIC Educational Resources Information Center

Quality control (QC) measures are less prevalent in teaching laboratories than commercial settings possibly owing to a lack of commercial incentives or teaching resources. This article focuses on the use of QC assessment in the analytical techniques of high performance liquid chromatography (HPLC) and ultraviolet-visible spectroscopy (UV-vis) at…

Schazmann, Benjamin; Regan, Fiona; Ross, Mary; Diamond, Dermot; Paull, Brett

2009-01-01

15

Introducing Quality Control in the Chemistry Teaching Laboratory Using Control Charts  

ERIC Educational Resources Information Center

|Quality control (QC) measures are less prevalent in teaching laboratories than commercial settings possibly owing to a lack of commercial incentives or teaching resources. This article focuses on the use of QC assessment in the analytical techniques of high performance liquid chromatography (HPLC) and ultraviolet-visible spectroscopy (UV-vis) at…

Schazmann, Benjamin; Regan, Fiona; Ross, Mary; Diamond, Dermot; Paull, Brett

2009-01-01

16

21 CFR 111.110 - What quality control operations are required for laboratory operations associated with the...  

Code of Federal Regulations, 2013 CFR

...2013-04-01 2013-04-01 false What quality control operations are required for laboratory...and Process Control System: Requirements for Quality Control § 111.110 What quality control operations are required for...

2013-04-01

17

Safeguards Analytical Laboratory Statistical Analysis of Wet Chemistry Quality Control Data.  

National Technical Information Service (NTIS)

This report examines quality control data for wet chemistry measurements made at Safeguards Analytical Laboratory (SAL), Seibersdorf, Austria. The statistical properties were evaluated for three data sets: (1) iron titer measurements, (2) percent bias fac...

C. K. Bayne

1989-01-01

18

An approach to quality and performance control in a computer-assisted clinical chemistry laboratory.  

PubMed Central

A locally developed, computer-based clinical chemistry laboratory system has been in operation since 1970. This utilises a Digital Equipment Co Ltd PDP 12 and an interconnected PDP 8/F computer. Details are presented of the performance and quality control techniques incorporated into the system. Laboratory performance is assessed through analysis of results from fixed-level control sera as well as from cumulative sum methods. At a simple level the presentation may be considered purely indicative, while at a more sophisticated level statistical concepts have been introduced to aid the laboratory controller in decision-making processes.

Undrill, P E; Frazer, S C

1979-01-01

19

Quality Control Laboratory Design Project for Poultry Science Undergraduate Students Enrolled in an Advanced Food Microbiology Course  

Microsoft Academic Search

An exercise for designing a quality control laboratory was developed as a laboratory group project in a senior level undergraduate advanced food microbiology course. The assignment was based on the student’s designing their own laboratory and implementing testing methods for different types of bacteria known to cause food-borne illness. Individual research papers and group project participation were required of each

R. S. Dittmar; M. M. Kundinger; C. L. Woodward; L. M. Donalson; J. L. Golbach; W. K. Kim; V. Chalova; S. C. Ricke

2006-01-01

20

Performance of automated slidemakers and stainers in a working laboratory environment - routine operation and quality control  

PubMed Central

The automated slidemaker/stainers of the four Beckman Coulter LH755 hematology systems in our laboratory are operated as analyzers, with similar requirements for setup, maintenance and quality control. A study was performed to confirm that these slide maker/stainers in routine use produce peripheral blood films that are completely satisfactory for microscopy and without cells, particularly abnormal cells, being pulled to the edges or sides of the film outside the usual working area. One hundred and thirty-nine automated blood films that had been produced during routine operation were compared with well-prepared manual films from the same patients. None of the films was unacceptable for microscopy. The distributions of normal white cell types within the counting areas of automated films compared with manual films, for all 139 samples for WBC from 1.0 to 352.8 × 109/l; for blasts and promyelocytes in the 65 samples in which they occurred and for nucleated red blood cells in the 58 samples in which they occurred all fell within the expected limits of 200 cell differential counts of CLSI H20-A. Red cell morphology and the occurrence of WBC clumps, platelet clumps and smudge cells were comparable between the automated and manual films of all samples. We conclude that automated slidemaker/stainers, as typified by those of the Beckman Coulter LH755 system, are capable of producing blood films comparable with well-prepared manual films in routine laboratory use; and that the maintenance and quality control procedures used in our laboratory ensure consistent high quality performance from these systems.

SIMSON, E; GASCON-LEMA, M G; BROWN, D L

2010-01-01

21

Quality assurance and quality control in forest soil analyses: a comparison between European soil laboratories  

Microsoft Academic Search

In transnational monitoring programmes, a balance between international reference methods, which improve spatial comparability, and national analysis methods that favour temporal comparability, by their use and testing over many years, needs to be sought. Prior to the next Pan-European Forest Soil Survey, a third interlaboratory comparison of soil analysis methods was organised. All participating laboratories were requested to use the

Nathalie Cools; Véronique Delanote; Xavier Scheldeman; Paul Quataert; Bruno De Vos; Peter Roskams

2004-01-01

22

A Preliminary Clinical Chemistry Laboratory Quality Control Programme for Addis Ababa.  

National Technical Information Service (NTIS)

A serum pool programme in clinical chemistry was started in Addis Ababa as a control for 5 participating laboratories. Basic statistical indices were calculated to determine the variation within each laboratory and to compare interlaboratory results. Stat...

C. P. Fulass R. Gillum

1973-01-01

23

Laboratory Evolution of Fast-Folding Green Fluorescent Protein Using Secretory Pathway Quality Control  

PubMed Central

Green fluorescent protein (GFP) has undergone a long history of optimization to become one of the most popular proteins in all of cell biology. It is thermally and chemically robust and produces a pronounced fluorescent phenotype when expressed in cells of all types. Recently, a superfolder GFP was engineered with increased resistance to denaturation and improved folding kinetics. Here we report that unlike other well-folded variants of GFP (e.g., GFPmut2), superfolder GFP was spared from elimination when targeted for secretion via the SecYEG translocase. This prompted us to hypothesize that the folding quality control inherent to this secretory pathway could be used as a platform for engineering similar ‘superfolded’ proteins. To test this, we targeted a combinatorial library of GFPmut2 variants to the SecYEG translocase and isolated several superfolded variants that accumulated in the cytoplasm due to their enhanced folding properties. Each of these GFP variants exhibited much faster folding kinetics than the parental GFPmut2 protein and one of these, designated superfast GFP, folded at a rate that even exceeded superfolder GFP. Remarkably, these GFP variants exhibited little to no loss in specific fluorescence activity relative to GFPmut2, suggesting that the process of superfolding can be accomplished without altering the proteins' normal function. Overall, we demonstrate that laboratory evolution combined with secretory pathway quality control enables sampling of largely unexplored amino-acid sequences for the discovery of artificial, high-performance proteins with properties that are unparalleled in their naturally occurring analogues.

Fisher, Adam C.; DeLisa, Matthew P.

2008-01-01

24

Quality Control Guidelines for National Committee for Clinical Laboratory Standards Recommended Broth Macrodilution Testing of Amphotericin B, Fluconazole, and Flucytosine  

Microsoft Academic Search

Amphotericin B, fluconazole, and flucytosine (5FC) were tested in a multilaboratory study to establish quality control (QC) guidelines for yeast antifungal susceptibility testing. Ten candidate QC strains were testedinaccordancewithNationalCommitteeforClinicalLaboratoryStandardsM27-Pguidelinesagainstthe three antifungal agents in each of six laboratories. Each laboratory was assigned a unique lot of RPMI 1640 broth medium as well as a lot of RPMI 1640 common to all

M. A. PFALLER; M. BALE; B. BUSCHELMAN; M. LANCASTER; A. ESPINEL-INGROFF; J. H. REX; M. G. RINALDI; C. R. COOPER; R. MCGINNIS

1995-01-01

25

Ability of laboratories to detect emerging antimicrobial resistance: proficiency testing and quality control results from the World Health Organization's external quality assurance system for antimicrobial susceptibility testing.  

PubMed

The accuracy of antimicrobial susceptibility data submitted by microbiology laboratories to national and international surveillance systems has been debated for a number of years. To assess the accuracy of data submitted to the World Health Organization by users of the WHONET software, the Centers for Disease Control and Prevention distributed six bacterial isolates representing key antimicrobial-resistance phenotypes to approximately 130 laboratories, all but one of which were outside of the United States, for antimicrobial susceptibility testing as part of the World Health Organization's External Quality Assurance System for Antimicrobial Susceptibility Testing. Each laboratory also was asked to submit 10 consecutive quality control values for several key organism-drug combinations. Most laboratories were able to detect methicillin (oxacillin) resistance in Staphylococcus aureus, high-level vancomycin resistance in Enterococcus faecium, and resistance to extended-spectrum cephalosporins in Klebsiella pneumoniae. Many laboratories, particularly those using disk diffusion tests, had difficulty in recognizing reduced susceptibility to penicillin in an isolate of Streptococcus pneumoniae. The most difficult phenotype for laboratories to detect was reduced susceptibility to vancomycin in an isolate of Staphylococcus epidermidis. The proficiency testing challenge also included a request for biochemical identification of a gram-negative bacillus, which most laboratories recognized as Enterobacter cloacae. Although only a small subset of laboratories have submitted their quality control data, it is clear that many of these laboratories generate disk diffusion results for oxacillin when testing S. aureus ATCC 25923 and S. pneumoniae ATCC 49619 that are outside of the acceptable quality control range. The narrow quality control range for vancomycin also proved to be a challenge for many of the laboratories submitting data; approximately 27% of results were out of range. Thus, it is important to establish the proficiency of laboratories submitting data to surveillance systems in which the organisms are tested locally, particularly for penicillin resistance in pneumococci and glycopeptide resistance in staphylococci. PMID:11136778

Tenover, F C; Mohammed, M J; Stelling, J; O'Brien, T; Williams, R

2001-01-01

26

222-S laboratory quality assurance plan  

Microsoft Academic Search

This document provides quality assurance guidelines and quality control requirements for analytical services. This document is designed on the basis of Hanford Analytical Services Quality Assurance Plan (HASQAP) technical guidelines and is used for governing 222-S and 222-SA analytical and quality control activities. The 222-S Laboratory provides analytical services to various clients including, but not limited to, waste characterization for

Meznarich

1995-01-01

27

QUALITY CONTROLS FOR PCR  

EPA Science Inventory

The purpose of this presentation is to present an overview of the quality control (QC) sections of a draft EPA document entitled, "Quality Assurance/Quality Control Guidance for Laboratories Performing PCR Analyses on Environmental Samples." This document has been prepared by th...

28

[Quality assurance in food microbiology laboratories].  

PubMed

In the paper the quality assurance system in food microbiology laboratories to ensure the reliability of the analytical data are discussed. To introduce quality assurance system in the laboratory all activities such as sampling, method selection, laboratory environment, equipment, reagents and media, staff, reference materials, internal quality control and external quality control (proficiency testing) that effect on the results must be documented and controlled. The kind of food sample, condition and time of storage before analysis and proper selection of methodology have significant influence on the result of the microbiological analysis. Equipment used to carry out the test must work properly. Implementation of of the internal and external quality control to the routine work of the food microbiology laboratory means that the production of the results is under control and that the data are reliable. If the quality assurance system is properly implemented and well documented it makes the base for the laboratory to get the accreditation. PMID:9102793

Cwiek-Ludwicka, K; Windyga, B; Kar?owski, K

1996-01-01

29

The use of near infrared spectroscopy in the quality control laboratory of the pharmaceutical industry.  

PubMed

The suitability of NIR spectroscopy as an alternative to several compendial test methods is discussed. Using ampicillin trihydrate as an example it is demonstrated that eight quality criteria are controlled by recording the NIR spectrum of a batch sample and calculating its Conformity Index. PMID:1298385

Plugge, W; van der Vlies, C

30

Evaluation of quality assurance\\/quality control data collected by the US Geological Survey for water-quality activities at the Idaho National Engineering Laboratory, Idaho, 1989 through 1993  

Microsoft Academic Search

Hundreds of water samples were collected by the US Geological Survey (USGS) from 177 monitoring sites for the water quality monitoring program at the Idaho National Engineering Laboratory from 1989 through 1993. Concurrently, replicate pairs of samples and various types of blank samples were collected as part of the quality assurance\\/quality control program. Analyses were performed to determine the concentrations

1996-01-01

31

Quality Control Guidelines for National Committee for Clinical Laboratory Standards-Recommended Broth Macrodilution Testing of Ketoconazole and Itraconazole  

Microsoft Academic Search

Ketoconazole and itraconazole were tested in a multilaboratory study to establish quality control (QC) guidelines for yeast antifungal susceptibility testing. Two isolates that had been previously identified as QC isolates for amphotericin B,fluconazole, andflucytosine (Candida parapsilosisATCC 22019 andCandida krusei ATCC 6258) were tested in accordance with the National Committee for Clinical Laboratory Standards M27-P guidelines. Each isolate was tested 20

JOHN H. REX; MICHAEL A. PFALLER; MICHAEL LANCASTER; FRANK C. ODDS; ANNE BOLMSTROM; ANDMICHAEL G. RINALDI

1996-01-01

32

Development, application, and quality control of serology assays used for diagnostic monitoring of laboratory nonhuman primates.  

PubMed

The careful development, validation, and implementation of serodiagnostic assays can provide reliable results that make them a valuable tool in microbial quality control for nonhuman primates. This article includes identification and description of the components of assay development, including formulas for calculating the number of positive serum samples needed for assay validation and methods for calculating their diagnostic sensitivity and specificity. To ensure that assays are performing within predetermined specifications, there must be a quality control system that includes appropriate system and sample suitability controls as well as mechanisms to track assay performance over time. The section on quality assurance includes definitions of precision and accuracy in assay performance, and how to interpret these two factors using the Levey-Jennings chart, Westgard's rules, and other monitoring methods. Because all serologic assays are prone to false positive and false negative results, it is essential to interpret all diagnostic test results using both the expected prevalence of disease in the population and the population-specific assay performance characteristics that are determined during assay validation. The discussion on interpreting diagnostic test results also includes guidelines for calculating the positive and negative predictive values of an assay and for interpreting results based on the disease prevalence of the test population. A glossary provides definitions of commonly used terms. PMID:18323578

Simmons, Joe H

2008-01-01

33

Optimal Policies for Clinical Laboratory Quality Control. Abstract and Executive Summary.  

National Technical Information Service (NTIS)

Mathematical and economic models are developed to help analyze and improve the overall sensitivity, specificity, and cost of laboratory sceening policies, with particular focus on the policy currently required by the Clinical Laboratory Improvements Amend...

J. C. Benneyan

1997-01-01

34

Quality in the molecular microbiology laboratory.  

PubMed

In the clinical microbiology laboratory advances in nucleic acid detection, quantification, and sequence analysis have led to considerable improvements in the diagnosis, management, and monitoring of infectious diseases. Molecular diagnostic methods are routinely used to make clinical decisions based on when and how to treat a patient as well as monitor the effectiveness of a therapeutic regime and identify any potential drug resistant strains that may impact on the long term patient treatment program. Therefore, confidence in the reliability of the result provided by the laboratory service to the clinician is essential for patient treatment. Hence, suitable quality assurance and quality control measures are important to ensure that the laboratory methods and service meet the necessary regulatory requirements both at the national and international level. In essence, the modern clinical microbiology laboratory ensures the appropriateness of its services through a quality management system that monitors all aspects of the laboratory service pre- and post-analytical-from patient sample receipt to reporting of results, from checking and upholding staff competency within the laboratory to identifying areas for quality improvements within the service offered. For most European based clinical microbiology laboratories this means following the common International Standard Organization (ISO9001) framework and ISO15189 which sets out the quality management requirements for the medical laboratory (BS EN ISO 15189 (2003) Medical laboratories-particular requirements for quality and competence. British Standards Institute, Bristol, UK). In the United States clinical laboratories performing human diagnostic tests are regulated by the Centers for Medicare and Medicaid Services (CMS) following the requirements within the Clinical Laboratory Improvement Amendments document 1988 (CLIA-88). This chapter focuses on the key quality assurance and quality control requirements within the modern microbiology laboratory providing molecular diagnostics. PMID:23104281

Wallace, Paul S; MacKay, William G

2013-01-01

35

[Approval of ISO/IEC 17025 and quality control of laboratory testing].  

PubMed

First section of Division of Biomedical Food Research, National Institute of Health Sciences (NIHS) was approved by ISO/IEC 17025 as a laboratory having an appropriate laboratory testing technique. NIHS is the first national laboratory approved by ISO/IEC 17025. NIHS has also been accepted the appropriate technique and facility for the BSL3 level pathogens by ISO/IEC 17025. NIHS is necessary to take an external audit almost every year. This approval is renewed every 4 years. PMID:21381399

Yamamoto, Shigeki; Asakura, Hiroshi; Machii, Kenji; Igimi, Shizunobu

2010-01-01

36

Quality assurance and quality control in light stable isotope laboratories: a case study of Rio Grande, Texas, water samples.  

PubMed

New isotope laboratories can achieve the goal of reporting the same isotopic composition within analytical uncertainty for the same material analysed decades apart by (1) writing their own acceptance testing procedures and putting them into their mass spectrometric or laser-based isotope-ratio equipment procurement contract, (2) requiring a manufacturer to demonstrate acceptable performance using all sample ports provided with the instrumentation, (3) for each medium to be analysed, prepare two local reference materials substantially different in isotopic composition to encompass the range in isotopic composition expected in the laboratory and calibrated them with isotopic reference materials available from the International Atomic Energy Agency (IAEA) or the US National Institute of Standards and Technology (NIST), (4) using the optimum storage containers (for water samples, sealing in glass ampoules that are sterilised after sealing is satisfactory), (5) interspersing among sample unknowns local laboratory isotopic reference materials daily (internationally distributed isotopic reference materials can be ordered at three-year intervals, and can be used for elemental analyser analyses and other analyses that consume less than 1 mg of material) - this process applies to H, C, N, O, and S isotope ratios, (6) calculating isotopic compositions of unknowns by normalising isotopic data to that of local reference materials, which have been calibrated to internationally distributed isotopic reference materials, (7) reporting results on scales normalised to internationally distributed isotopic reference materials (where they are available) and providing to sample submitters the isotopic compositions of internationally distributed isotopic reference materials of the same substance had they been analysed with unknowns, (8) providing an audit trail in the laboratory for analytical results - this trail commonly will be in electronic format and might include a laboratory information management system, (9) making at regular intervals a complete backup of laboratory analytical data (both of samples logged into the laboratory and of mass spectrometric analyses), being sure to store one copy of this backup offsite, and (10) participating in interlaboratory comparison exercises sponsored by the IAEA and other agencies at regular intervals. PMID:20183226

Coplen, Tyler B; Qi, Haiping

2009-06-01

37

Statistical quality control procedures.  

PubMed

The right quality control (QC) should ensure the detection of important errors. Statistical QC (SQC) should be included in all QC plans. The Clinical and Laboratory Standards Institute (CLSI) C24A3 provides guidance for the application of SQC in medical laboratories. It describes a QC planning process and provides an SQC selection tool that relates the sigma-metric of a testing process to the medically important systematic error and the rejection characteristics of different SQC procedures. Once the right SQC has been selected, the laboratory must implement SQC right. CLSI C24A3 also provides guidance for establishing run length and control limits. PMID:23331732

Westgard, James O

2012-12-20

38

Statistical Methods for Establishing Quality Control Ranges for Antibacterial Agents in Clinical and Laboratory Standards Institute Susceptibility Testing?  

PubMed Central

Quality control (QC) ranges for antimicrobial agents against QC strains for both dilution and disk diffusion testing are currently set by the Clinical and Laboratory Standards Institute (CLSI), using data gathered in predefined structured multilaboratory studies, so-called tier 2 studies. The ranges are finally selected by the relevant CLSI subcommittee, based largely on visual inspection and a few simple rules. We have developed statistical methods for analyzing the data from tier 2 studies and applied them to QC strain-antimicrobial agent combinations from 178 dilution testing data sets and 48 disk diffusion data sets, including a method for identifying possible outlier data from individual laboratories. The methods are based on the fact that dilution testing MIC data were log normally distributed and disk diffusion zone diameter data were normally distributed. For dilution testing, compared to QC ranges actually set by CLSI, calculated ranges were identical in 68% of cases, narrower in 7% of cases, and wider in 14% of cases. For disk diffusion testing, calculated ranges were identical to CLSI ranges in 33% of cases, narrower in 8% of cases, and 1 to 2 mm wider in 58% of cases. Possible outliers were detected in 8% of diffusion test data but none of the disk diffusion data. Application of statistical techniques to the analysis of QC tier 2 data and the setting of QC ranges is relatively simple to perform on spreadsheets, and the output enhances the current CLSI methods for setting of QC ranges.

Turnidge, John; Bordash, Gerry

2007-01-01

39

Methods of Analysis by the U.S. Geological Survey National Water Quality Laboratory - Processing, Taxonomy, and Quality Control of Benthic Macroinvertebrate Samples.  

National Technical Information Service (NTIS)

Qualitative and quantitative methods to process benthic macroinvertebrate (BMI) samples have been developed and tested by the U.S. Geological Survey's National Water Quality Laboratory Biological Group. The qualitative processing method is based on v...

I. S. Moulton J. L. Carter S. A. Grotheer T. F. Cuffney T. M. Short

2000-01-01

40

Proposed quality control guidelines for National Committee for Clinical Laboratory Standards Susceptibility Tests using the veterinary antimicrobial agent tiamulin  

Microsoft Academic Search

Quality control guidelines for standardized antimicrobial susceptibility test methods are critical for the continuing accuracy of these clinical tests. In this report, quality control limits were proposed for the veterinary antimicrobial agent tiamulin with minimum inhibitory concentration (MIC) ranges of three or four log2 dilution steps in two different medium formulations. Disk diffusion zone diameter ranges were proposed for tiamulin

Michael A Pfaller; Ronald N Jones; Donald H Walter

2001-01-01

41

ASVCP quality assurance guidelines: control of preanalytical and analytical factors for hematology for mammalian and nonmammalian species, hemostasis, and crossmatching in veterinary laboratories.  

PubMed

In December 2009, the American Society for Veterinary Clinical Pathology (ASVCP) Quality Assurance and Laboratory Standards committee published the updated and peer-reviewed ASVCP Quality Assurance Guidelines on the Society's website. These guidelines are intended for use by veterinary diagnostic laboratories and veterinary research laboratories that are not covered by the US Food and Drug Administration Good Laboratory Practice standards (Code of Federal Regulations Title 21, Chapter 58). The guidelines have been divided into 3 reports: (1) general analytical factors for veterinary laboratory performance and comparisons; (2) hematology, hemostasis, and crossmatching; and (3) clinical chemistry, cytology, and urinalysis. This particular report is one of 3 reports and provides recommendations for control of preanalytical and analytical factors related to hematology for mammalian and nonmammalian species, hemostasis testing, and crossmatching and is adapted from sections 1.1 and 2.3 (mammalian hematology), 1.2 and 2.4 (nonmammalian hematology), 1.5 and 2.7 (hemostasis testing), and 1.6 and 2.8 (crossmatching) of the complete guidelines. These guidelines are not intended to be all-inclusive; rather, they provide minimal guidelines for quality assurance and quality control for veterinary laboratory testing and a basis for laboratories to assess their current practices, determine areas for improvement, and guide continuing professional development and education efforts. PMID:22390423

Vap, Linda M; Harr, Kendal E; Arnold, Jill E; Freeman, Kathleen P; Getzy, Karen; Lester, Sally; Friedrichs, Kristen R

2012-03-01

42

[Total quality management in laboratory medicine].  

PubMed

The German Public Health will be continuously challenged in the future. It has to be assumed that modified managed care will not only take place sporadically. Thus, quality aspects of services gain more and more significance. Only suppliers will be successful who can offer services of highest quality at lowest prices. Quality in a comprehensive sense has to be substantiated in the near future. It is recommended to apply industry proven models also in public health service. Medical laboratories can be pioneers in this field as they have been already in the past. All previously proposed procedures can not describe quality of results comprehensively. They are based to a high degree on external control. Total quality management, however, represents a comprehensive approach. Principles are zero-defect approach, customer orientation and system management. Quality is given in the sense of TQM if the customer is permanently satisfied with the service of the supplier. In such a way, the customer defines quality of service. A customer is everyone who receives products or services. TQM overcomes the drawbacks of quality management systems, which are strongly formal and oriented by external control, as accreditation (EN 45,000) or certification (ISO 9000). Competition between hospitals is a declared goal of German health politics because usually quality is increased and cost decreased as a consequence. Competition means also comparison of services. TQM emphasizes benchmarking especially among the best suppliers. PMID:10028601

Vogt, W

1998-12-01

43

222-S laboratory quality assurance plan  

SciTech Connect

This document provides quality assurance guidelines and quality control requirements for analytical services. This document is designed on the basis of Hanford Analytical Services Quality Assurance Plan (HASQAP) technical guidelines and is used for governing 222-S and 222-SA analytical and quality control activities. The 222-S Laboratory provides analytical services to various clients including, but not limited to, waste characterization for the Tank Waste Remediation Systems (TWRS), waste characterization for regulatory waste treatment, storage, and disposal (TSD), regulatory compliance samples, radiation screening, process samples, and TPA samples. A graded approach is applied on the level of sample custody, QC, data verification, and data reporting to meet the specific needs of the client.

Meznarich, H.K.

1995-04-01

44

Quality control in urinalysis.  

PubMed

Quality control (QC) has been introduced in laboratories, and QC surveys in urinalysis have been performed by College of American Pathologist, by Japanese Association of Medical Technologists, by Osaka Medical Association and by manufacturers. QC survey in urinalysis for synthetic urine by the reagent strip and instrument made in same manufacturer, and by an automated urine cell analyser provided satisfactory results among laboratories. QC survey in urinalysis for synthetic urine by the reagent strips and instruments made by various manufacturers indicated differences in the determination values among manufacturers, and between manual and automated methods because the reagent strips and instruments have different characteristics, respectively. QC photo survey in urinalysis on the microscopic photos of urine sediment constituents indicated differences in the identification of cells among laboratories. From the results, it is necessary to standardize a reagent strip method, manual and automated methods, and synthetic urine. PMID:10926274

Takubo, T; Tatsumi, N

1999-01-01

45

[Statistical approach to evaluate the occurrence of out-of acceptable ranges and accuracy for antimicrobial susceptibility tests in inter-laboratory quality control program].  

PubMed

To evaluate the occurrence of out-of acceptable ranges and accuracy of antimicrobial susceptibility tests, we applied a new statistical tool to the Inter-Laboratory Quality Control Program established by the Kyushu Quality Control Research Group. First, we defined acceptable ranges of minimum inhibitory concentration (MIC) for broth microdilution tests and inhibitory zone diameter for disk diffusion tests on the basis of Clinical and Laboratory Standards Institute (CLSI) M100-S21. In the analysis, more than two out-of acceptable range results in the 20 tests were considered as not allowable according to the CLSI document. Of the 90 participating laboratories, 46 (51%) experienced one or more occurrences of out-of acceptable range results. Then, a binomial test was applied to each participating laboratory. The results indicated that the occurrences of out-of acceptable range results in the 11 laboratories were significantly higher when compared to the CLSI recommendation (allowable rate < or = 0.05). The standard deviation indices(SDI) were calculated by using reported results, mean and standard deviation values for the respective antimicrobial agents tested. In the evaluation of accuracy, mean value from each laboratory was statistically compared with zero using a Student's t-test. The results revealed that 5 of the 11 above laboratories reported erroneous test results that systematically drifted to the side of resistance. In conclusion, our statistical approach has enabled us to detect significantly higher occurrences and source of interpretive errors in antimicrobial susceptibility tests; therefore, this approach can provide us with additional information that can improve the accuracy of the test results in clinical microbiology laboratories. PMID:23785793

Ueno, Tamio; Matuda, Junichi; Yamane, Nobuhisa

2013-03-01

46

Quality Control Microbiologist  

NSDL National Science Digital Library

This video, presented by WGBH, takes a look at a day in the life of a quality control microbiologist at a pharmaceutical company and provides a detailed account of what is possible with a microbiology degree, including the hands-on laboratory aspects field. This video would be helpful for anyone interested in a degree in microbiology, as well as anyone that is currently earning a degree in this field but is still unsure about what to do with it. Educators will also find a background essay, discussion questions, and standards alignment for the material. Running time for the video is 2:38.

2010-10-12

47

[Quality control in parasitology].  

PubMed

Between 1990 and 1996 we coordinated a Quality Control (QC) Program in Parasitology directed to Public Health Institutions in Spain. Periodically, parasited specimens, mainly feces or blood, were sent to Microbiology Laboratories for identification. Each QC was accompanied by a short clinic and epidemiological information in order to help in the diagnostic approach. After the answers to the QC were received a bulletin that included the solution to the QC, comments on the several answers received and a chapter with parasitological themes related with the QC, was sent to each participating Laboratory. The bulletin was accompanied by a card that included a photograph and a short description of the organism object of the QC. PMID:12056259

Vasallo Matilla, F

2001-01-01

48

Evaluation of quality assurance/quality control data collected by the U.S. Geological Survey for water-quality activities at the Idaho National Engineering and Environmental Laboratory, Idaho, 1994 through 1995  

SciTech Connect

More than 4,000 water samples were collected by the US Geological Survey (USGS) from 179 monitoring sites for the water-quality monitoring program at the Idaho National Engineering Laboratory from 1994 through 1995. Approximately 500 of the water samples were replicate or blank samples collected for the quality assurance/quality control program. Analyses were performed to determine the concentrations of major ions, nutrients, trace elements, gross radioactivity and radionuclides, total organic carbon, and volatile organic compounds in the samples. To evaluate the precision of field and laboratory methods, analytical results of the replicate pairs of samples were compared statistically for equivalence on the basis of the precision associated with each result. In all, the statistical comparison of the data indicated that 95% of the replicate pairs were equivalent. Within the major ion analyses, 97% were equivalent; nutrients, 88%; trace elements, 95%; gross radioactivity and radionuclides, 93%; and organic constituents, 98%. Ninety percent or more of the analytical results for each constituent were equivalent, except for nitrite, orthophosphate, phosphorus, aluminum, iron, strontium-90, and total organic carbon.

Williams, L.M.

1997-03-01

49

ELEMENTS OF A LABORATORY QUALITY ASSURANCE PROGRAM  

EPA Science Inventory

The importance of Quality Assurance is discussed. The requirements of a quality assurance program are divided into three functions; namely, the Control of Quality, the Determination of Quality, and the Documentation of Quality. The Control of Quality is defined as the regulation ...

50

Indoor Air Quality in Chemistry Laboratories.  

ERIC Educational Resources Information Center

This paper presents air quality and ventilation data from an existing chemical laboratory facility and discusses the work practice changes implemented in response to deficiencies in ventilation. General methods for improving air quality in existing laboratories are presented and investigation techniques for characterizing air quality are…

Hays, Steve M.

51

Indoor Air Quality in Chemistry Laboratories.  

ERIC Educational Resources Information Center

|This paper presents air quality and ventilation data from an existing chemical laboratory facility and discusses the work practice changes implemented in response to deficiencies in ventilation. General methods for improving air quality in existing laboratories are presented and investigation techniques for characterizing air quality are…

Hays, Steve M.

52

7 CFR 90.103 - Maintenance of quality control records.  

Code of Federal Regulations, 2013 CFR

... 2013-01-01 false Maintenance of quality control records. 90.103 Section 90...LABORATORY TESTING PROGRAMS INTRODUCTION Quality Assurance § 90.103 Maintenance of quality control records. Quality control...

2013-01-01

53

Evaluation of quality assurance/quality control data collected by the US Geological Survey for water-quality activities at the Idaho National Engineering Laboratory, Idaho, 1989 through 1993  

SciTech Connect

Hundreds of water samples were collected by the US Geological Survey (USGS) from 177 monitoring sites for the water quality monitoring program at the Idaho National Engineering Laboratory from 1989 through 1993. Concurrently, replicate pairs of samples and various types of blank samples were collected as part of the quality assurance/quality control program. Analyses were performed to determine the concentrations of major ions, nutrients, trace elements, gross radioactivity and radionuclides, organic compounds, and total organic carbon in the samples. To evaluate the precision of field and laboratory methods, analytical results of the replicate pairs of samples were compared statistically for equivalence on the basis of the precision associated with each result. Ninety percent or more of the analytical results for each constituent were equivalent, except for ammonia plus organic nitrogen, orthophosphate, iron, manganese, radium-226, total organic carbon, and total phenols. Blank-sample analytical results indicated that the inorganic-free blank water from the USGS Quality of Water Service Unit and the deionized water from the USGS Idaho Falls Field Office were suitable source solutions for blanks. Waters from other sources were found to be unsatisfactory as blank source solutions. Results of the analyses of several equipment blanks were evaluated to determine if a bias had been introduced and the possible sources of the bias. All of the equipment blank analytical results indicated that ammonia concentrations were greater than the reporting level. None of the equipment blanks had measurable concentrations of radioactivity. Eight percent of the analyses for inorganic constituents showed measurable concentrations were present in the blanks, nine percent for radioactive constituents, and less than one percent for organic constituents.

Williams, L.M.

1996-06-01

54

Quality Leadership and Quality Control  

PubMed Central

Different quality control rules detect different analytical errors with varying levels of efficiency depending on the type of error present, its prevalence and the number of observations. The efficiency of a rule can be gauged by inspection of a power function graph. Control rules are only part of a process and not an end in itself; just as important are the trouble-shooting systems employed when a failure occurs. 'Average of patient normals' may develop as a usual adjunct to conventional quality control serum based programmes. Acceptable error can be based on various criteria; biological variation is probably the most sensible. Once determined, acceptable error can be used as limits in quality control rule systems. A key aspect of an organisation is leadership, which links the various components of the quality system. Leadership is difficult to characterise but its key aspects include trust, setting an example, developing staff and critically setting the vision for the organisation. Organisations also have internal characteristics such as the degree of formalisation, centralisation, and complexity. Medical organisations can have internal tensions because of the dichotomy between the bureaucratic and the shadow medical structures.

Badrick, Tony

2003-01-01

55

Certification of analytical laboratories — An integral part of the introduction of comprehensive production quality-control systems in industry  

Microsoft Academic Search

We will consider the problem of certifying industrial analytical laboratories which measure the composition and properties of materials. The particular features of the operation of analytical laboratories are as follows: The majority of measurements of the composition of materials are measurement experiments consisting of a number of simple measurements and auxiliary operations, the nature and sequence of which are regulated

V. I. Vinnik; E. Yu. Gusarskii; G. A. Petrova; A. Ya. Samokhina; N. G. Semenko

1978-01-01

56

Quality in Bibliographic Control.  

ERIC Educational Resources Information Center

|Discusses the quality of cataloging in bibliographic control based on experiences at the Library of Congress. Highlights include the down side of quality and quality review, copy cataloging, CONSER (Cooperative Online Serials), NCCP (National Coordinated Cataloging Program) and PCC (Program for Cooperative Cataloging), minimal-level cataloging,…

Thomas, Sarah E.

1996-01-01

57

Evaluation of Quality-Assurance/Quality-Control Data Collected by the U.S. Geological Survey from Wells and Springs between the Southern Boundary of the Idaho National Engineering and Environmental Laboratory and the Hagerman Area, Idaho, 1989 through 1995  

SciTech Connect

The U.S. Geological (USGS) and the Idaho Department of Water Resources, in cooperation with the U.S. Department of Energy, collected and analyzed water samples to monitor the water quality of the Snake River Plain aquifer from the southern boundary of the Idaho National Engineering and Environmental Laboratory to the Hagerman area, Idaho. Concurrently, replicate samples and blank samples were collected and analyzed as part of the quality-assurance/quality-control program. Samples were analyzed from inorganic constituents, gross radioactivity and radionuclides, organic constituents, and stable isotopes. To evaluate the precision of field and laboratory methods, analytical results of the water-quality and replicate samples were compared statistically for equivalence on the basis of the precision associated with each result. Statistical comparisons of the data indicated that 95 percent of the results of the replicate pairs were equivalent. Blank-sample analytical results indicated th at the inorganic blank water and volatile organic compound blank water from the USGS National Water Quality Laboratory and the distilled water from the Idaho Department of Water Resources were suitable for blanks; blank water from other sources was not. Equipment-blank analytical results were evaluated to determine if a bias had been introduced and possible sources of bias. Most equipment blanks were analyzed for trace elements and volatile organic compounds; chloroform was found in one equipment blank. Two of the equipment blanks were prepared after collection and analyses of the water-quality samples to determine whether contamination had been introduced during the sampling process. Results of one blank indicated that a hose used to divert water away from pumps and electrical equipment had contaminated the samples with some volatile organic compounds. Results of the other equipment blank, from the apparatus used to filter dissolved organic carbon samples, indicated that the filtering apparatus did not affect water-quality samples.

Williams, L.M.; Bartholomay, R.C.; Campbell, L.J.

1998-10-01

58

Quality Control in Evaluation.  

ERIC Educational Resources Information Center

Quality control in the auditing profession has developed useful practices that are applied to the research and evaluation process. By identifying and controlling sources of bias and noise in the system of inquiry, the quality of evaluative evidence can be enhanced for both present and future use. (Author/BS)

Trochim, William M. K.; Visco, Ronald J.

1985-01-01

59

Randomized trial interpreting sputum quality in a clinical laboratory.  

PubMed Central

The role for laboratory interpretation of microbiologic results remains controversial, and many laboratories leave the interpretation of culture results entirely to physicians. We examined the effects of furnishing a laboratory interpretation of sputum quality on physician decision making. Quality of sputum was determined on Gram-stained smears by using a modification of the criteria of Bartlett (R. C. Bartlett, Medical Microbiology: Quality, Cost, and Clinical Relevance, p. 24-31, 1974). A total of 301 poor-quality specimens were randomized either to receive written interpretation of Gram stain results or to a control group for which Gram stain results were reported without interpretation. Physicians were more likely to follow up a poor-quality specimen with a second specimen if they had been furnished an interpretation of the results from the original Gram stain (22 versus 12%; P = 0.025). We conclude that laboratory-based interpretation of microbiologic results can improve physician decision making.

Mizrachi, H H; Valenstein, P N

1987-01-01

60

21 CFR 606.140 - Laboratory controls.  

Code of Federal Regulations, 2010 CFR

...2009-04-01 false Laboratory controls. 606.140 Section 606...HUMAN SERVICES (CONTINUED) BIOLOGICS CURRENT GOOD MANUFACTURING...BLOOD COMPONENTS Laboratory Controls § 606.140 Laboratory controls. Laboratory control...

2009-04-01

61

21 CFR 606.140 - Laboratory controls.  

Code of Federal Regulations, 2013 CFR

...2013-04-01 false Laboratory controls. 606.140 Section 606...HUMAN SERVICES (CONTINUED) BIOLOGICS CURRENT GOOD MANUFACTURING...BLOOD COMPONENTS Laboratory Controls § 606.140 Laboratory controls. Laboratory control...

2013-04-01

62

21 CFR 606.140 - Laboratory controls.  

Code of Federal Regulations, 2010 CFR

...2010-04-01 false Laboratory controls. 606.140 Section 606...HUMAN SERVICES (CONTINUED) BIOLOGICS CURRENT GOOD MANUFACTURING...BLOOD COMPONENTS Laboratory Controls § 606.140 Laboratory controls. Laboratory control...

2010-04-01

63

[Guidelines for quality management of laboratory information systems].  

PubMed

After a short presentation of the SFIL, this article presents the working parties initiated by the SFIL. At the end of each of these works were published texts, recommendations and tools for the biologists and vendors, in order that the laboratory information system becomes a component of medical laboratory quality. Recommendations for quality control of information systems, resulting from these documents, are presented. PMID:23765024

Otter, M; Domas, G

2013-06-01

64

Perspectives on quality control, risk management, and analytical quality management.  

PubMed

Quality control (QC) practices are changing in US laboratories as Centers for Medicare and Medicaid Services adopts individualized QC plans as a new option for compliance with the Clinical Laboratory Improvement Amendments regulations. The Joint Commission provides general guidance for applying risk management in health care organizations. The EP23A (Evaluation Protocol 23A) document from the Clinical and Laboratory Standards Institute provides specific guidance on the use of risk management for developing analytical QC plans. Medical laboratories should integrate risk management tools with existing quality management techniques and activities to provide an overall plan for analytical quality management. PMID:23331725

Westgard, James O

2012-12-20

65

RCL - Remotely Controlled Laboratories  

NSDL National Science Digital Library

The purpose of this web site is to provide Remote Controlled Labs (RCLs) to users on the internet. These are real experiments which can be executed by a client using a standard web browser interacting with a web server controlling the experiment. Web cams allow the user to observe the on-going experiment. The experiments are designed to encourage interactive exploration by students and emphasize the importance of experiments in physics. The labs available include Millikan's oil-drop experiment, Rutherford scattering, the speed of light, the photoelectric effect, I-V characteristics, radioactivity, and control of robots.

2009-02-07

66

Total quality management in clinical virology laboratories.  

PubMed

The diagnostic laboratories in India are progressively promoting higher standards and are moving towards accreditation and international acceptance. Hence, the concept of "Quality" will need to be understood and implemented. Total quality management (TQM) in a laboratory is an integrated program involving all laboratory staff and management. TQM is a framework to operate and it is aiming for integration, consistency, increase in efficiency and a continuous drive for improvement. A well structured clinical virology service will include serology setup, cell culture facility and capacity for molecular diagnosis. The quality of results from the laboratory is significantly influenced by many pre-analytical and post-analytical factors which needed attention. The end goal of the TQM should be to provide the best care possible for the patient. PMID:17185843

Tibbets, M W; Gomez, R; Kannangai, R; Sridharan, G

2006-10-01

67

Implementing total quality management (TQM) in health-care laboratories.  

PubMed

Health-care organizations are beginning to apply the principles of total quality management (TQM). Implementing TQM in a health-care laboratory requires incorporating quality improvement (QI) and quality planning (QP) with quality laboratory practices (QLP), quality control (QC), and quality assurance (QA) to provide a complete quality management system. QI and QP can be initiated by developing a strategic plan as a pilot QI project. QI project teams are then introduced to accomplish the highest priority goals. This implementation approach improves strategic planning by using group problem-solving tools and techniques, such as process flow charts, brainstorming, nominal group, fishbone diagrams, consensus decision making, and Pareto analysis. The approach also improves the success of project teams by providing a clear management agenda and a commitment to project-by-project QI. PMID:10113715

Westgard, J O; Barry, P L; Tomar, R H

68

Quality in Bibliographic Control  

Microsoft Academic Search

~IBSTRACT THE QUKIW OF CATALOGING IS AU ISSUE that has engendered much discussion over decades of bibliographic control. Juxtaposed against the standard of full, accurate, and timely bibliographic records is the pressure to pro- duce reliable access in a cost-effective manner. In reviewing the defini- tion of quality at the Library of Congress (LC),the relationship of quality cataloging to copy

Sarah E. Thomas

1996-01-01

69

222-S Laboratory Quality Assurance Plan. Revision 1  

SciTech Connect

This Quality Assurance Plan provides,quality assurance (QA) guidance, regulatory QA requirements (e.g., 10 CFR 830.120), and quality control (QC) specifications for analytical service. This document follows the U.S Department of Energy (DOE) issued Hanford Analytical Services Quality Assurance Plan (HASQAP). In addition, this document meets the objectives of the Quality Assurance Program provided in the WHC-CM-4-2, Section 2.1. Quality assurance elements required in the Guidelines and Specifications for Preparing Quality Assurance Program Plans (QAMS-004) and Interim Guidelines and Specifications for Preparing Quality Assurance Project Plans (QAMS-005) from the US Environmental Protection Agency (EPA) are covered throughout this document. A quality assurance index is provided in the Appendix A. This document also provides and/or identifies the procedural information that governs laboratory operations. The personnel of the 222-S Laboratory and the Standards Laboratory including managers, analysts, QA/QC staff, auditors, and support staff shall use this document as guidance and instructions for their operational and quality assurance activities. Other organizations that conduct activities described in this document for the 222-S Laboratory shall follow this QA/QC document.

Meznarich, H.K.

1995-07-31

70

Emerging concepts of quality assurance in clinical laboratories.  

PubMed

Quality Assurance is a management system designed to achieve an acceptable level of quality services, prevent poor quality and in laboratories is intended to ensure reliability of results. It comprehensively includes controlling the quality of procedures at each and every step including Pre-analytical (specimen collection and transport), Analytical (specimen processing in the lab) and Post-analytical (reporting and interpretation of results). Concept of total quality management (TQM) is closely interlinked with good laboratory practices and goes far beyond the widely practiced conventional Quality Control (QC) procedures. TQM includes Technical accuracy and precision, equipment and supplies, staff training and skill, financial management (cost effectiveness), lab safety, communication etc. Recent pressures on pathology laboratories have meant that laboratories no longer have the numbers of scientists and pathologists they had in the past. This has resulted in more questions being asked of the QA staff with a steady increase in the number of scientists employed to address this demand. Quality improvement in the modern clinical laboratory environment entails the continuous inspection and refinement of processes to ensure the efficient delivery of services that meet the needs and expectations of those who use them. PMID:17091755

Naz, Sumera; Saddar-ud-din, Agha

2006-09-01

71

Information systems as a quality management tool in clinical laboratories  

NASA Astrophysics Data System (ADS)

This article describes information systems as a quality management tool in clinical laboratories. The quality of laboratory analyses is of fundamental importance for health professionals in aiding appropriate diagnosis and treatment. Information systems allow the automation of internal quality management processes, using standard sample tests, Levey-Jennings charts and Westgard multirule analysis. This simplifies evaluation and interpretation of quality tests and reduces the possibility of human error. This study proposes the development of an information system with appropriate functions and costs for the automation of internal quality control in small and medium-sized clinical laboratories. To this end, it evaluates the functions and usability of two commercial software products designed for this purpose, identifying the positive features of each, so that these can be taken into account during the development of the proposed system.

Schmitz, Vanessa; Rosecler Bez el Boukhari, Marta

2007-11-01

72

Software Quality-Control Program,  

National Technical Information Service (NTIS)

The overall standards of the program stipulate policies and procedures for implementing economical yet efficient software quality control. The program is designed for quality-control organization and policy control as well as quality assurance and mainten...

I. Nakane H. Kobayashi T. Tsuchiya M. Masuda

1988-01-01

73

[External quality control of the laboratory determination of glucose in the urine and material for its realization].  

PubMed

Urine of diabetics without concomitant diseases with a certain concentration of glucose was collected for preparing reference material. Water saturated with phenol (872 mmole/liter) was added to urine pool during intensive stirring on a magnetic stirrer at 20 degrees C, so that the final concentration of phenol were 50 mmole/liter. Glucose content in the resultant reference material remained stable for 130 days at 18-20 degrees C. For glucose measurements, 2 ml reference material and 0.5 ml 2.5 M sodium oxide hydrate are put in centrifuge tubes, stirred, put on boiling water bath for 2 min, cooled, and colorimetried in cuvettes with 1-mm optic route. The content of monosaccharide is calculated using the proportion rule in comparison with the values for 139 mM reference glucose solution in control urine. PMID:10205658

Iarmol'chuk, S G

1998-11-01

74

Implementation of a quality management system in public health laboratories in the Republic of Georgia  

Microsoft Academic Search

Through a cooperative agreement with the Centers for Disease Control and Prevention (CDC), the Clinical and Laboratory Standards Institute and CDC Laboratory Strengthening Department implemented quality management systems (QMS) into the two national public health laboratories in Tbilisi, Georgia. The QMS was based on CLSI's document Quality Management System: A Model for Laboratory Services; Approved Guideline and ISO 15189, Medical

Brandy Greenhill

2012-01-01

75

Simple and inexpensive control laboratory  

Microsoft Academic Search

To address the basic problem of teaching fundamentals of control theory, a one-credit-hour control laboratory is proposed. The three-lecture-hour introductory control course is replaced with a four-hour lecture-lab course. This proposed lab is simple and inexpensive enough that any electrical engineering department with any shrinking budget, with the help of NSF matching fund, can afford to have it. The experiments

A. Davari; D. Shen

1997-01-01

76

Interaction between production control and quality control  

Microsoft Academic Search

Describes a qualitative study on interaction between systems for production control and quality control within industrial organisations. Production control and quality control interact in a sense. Good performance for one aspect often influences or frustrates the performance of the other. As far as is known, the phenomenon of interaction between production control and quality control has not been described extensively

Hans van der Bij; Jeroen H. W. van Ekert

1999-01-01

77

Expert System Quality Control.  

ERIC Educational Resources Information Center

A consultation quality control model (CQCM) developed for an expert system (ES) integrated both ES performance measures and end-user judgment values. Simple decision theory concepts were used to design the CQCM. Results show end users belong to different categories characterized by utility functions and the weights they assign to ES consultation…

Raggad, Bel Gacem

1996-01-01

78

SIMBAD Quality-Control  

NASA Astrophysics Data System (ADS)

Taking into consideration the amount and the complexity of SIMBAD data, it is necessary to use automatic methods to control and assure the quality of the SIMBAD database. One possibility is to apply multivariate data analysis to the content of documents related to astronomical data. The method and first results are presented.

Lesteven, Soizick

1993-01-01

79

Control of the Coffee Fermentation Process and Quality of Resulting Roasted Coffee: Studies in the Field Laboratory and on Small Farms in Nicaragua During the 2005-06 Harvest  

Microsoft Academic Search

Summary This paper describes a field study conducted during the 2005-06 Nicaraguan coffee harvest investigating the relationship between scientific control of the coffee fermenta- tion process and the quality of the resulting roasted coffee. In phase one of the study, small-scale, well-controlled laboratory fermentation was carried out on eleven batches of coffee at the farm La Canavalia in Matagalpa, Nicaragua.

S. JACKELS; C. JACKELS; C. VALLEJOS; S. KLEVEN; R. RIVAS

80

Quality Assurance: Are Laboratories Assuring, Assessing, or Assuming the Quality of Clinical Testing Today?  

Microsoft Academic Search

Quality assurance implies making certain, guaranteeing the attainment of quality. Do laboratories actually guarantee the quality of testing services today? If not, what is the purpose of quality assurance plans, programs, and practices? Have laboratories even defined the quality to be achieved for each test? If not, how can quality be guaranteed? Do current efforts in assessing quality provide for

James O. Westgard

81

Evaluation of Quality-Assurance\\/Quality-Control Data Collected by the U.S. Geological Survey from Wells and Springs between the Southern Boundary of the Idaho National Engineering and Environmental Laboratory and the Hagerman Area, Idaho, 1989 through 1995  

Microsoft Academic Search

The U.S. Geological (USGS) and the Idaho Department of Water Resources, in cooperation with the U.S. Department of Energy, collected and analyzed water samples to monitor the water quality of the Snake River Plain aquifer from the southern boundary of the Idaho National Engineering and Environmental Laboratory to the Hagerman area, Idaho. Concurrently, replicate samples and blank samples were collected

L. M. Williams; R. C. Bartholomay; L. J. Campbell

1998-01-01

82

Quality assurance in home laboratory testing.  

PubMed

In review, one is compelled to the notion that a variety of the aforementioned thoughts become pre-eminent in assuring quality. The selection of the tests available for home testing is crucial. They should be divided into categories of single encounter tests and multiple use tests. The single encounter implies a test that has an extremely high degree of reliability and is likely to achieve an answer to the question asked. This should relate to a disease or process for which potential favorable treatment can be achieved or which may have a major favorable impact on public health. In this category one thinks in terms of the worldwide prevalence of hepatitis B and other infectious diseases that are particularly common in third world countries. Yet, these are not "markets" likely to be able to afford this testing. Similarly, these societies are not currently sophisticated in terms of application of preventive measures. On the other hand, major benefits could be projected from the other category of testing, namely, therapeutic monitoring in the hands of individuals who will repetitively test for the same substance in the same manner. This includes not only diabetes but other conditions that are monitored for drug therapy, including seizure disorders and bronchospasm. Inherent in this aspect is the requirement for meaningful and ongoing instruction in proper testing methodology and recording of results. The incorporation of some type of memory device to enforce this aspect of testing appears extremely desirable, if not mandatory. Finally, we must consider the potential for misuse of the single test type of device. One suspects that it would be highly desirable that any test made available for self-testing should also be mandated as accessible through certified laboratories at the request of an individual, which would at least provide reliable performance of the test with a quality result. The development of the concept of quality assurance in home testing is in its infancy and will require continuing evolution. PMID:3791913

Keffer, J H

1986-12-01

83

Cost Effectiveness of Adopted Quality Requirements in Hospital Laboratories  

PubMed Central

Background The present study was designed in quasi-experiment to assess adoption of the essential clauses of particular clinical laboratory quality management requirements based on international organization for standardization (ISO 15189) in hospital laboratories and to evaluate the cost effectiveness of compliance to ISO 15189. Methods: The quality management intervention based on ISO 15189 was conceded through three phases; pre – intervention phase, Intervention phase and Post-intervention phase. Results: In pre-intervention phase the compliance to ISO 15189 was 49% for study group vs. 47% for control group with P value 0.48, while the post intervention results displayed 54% vs. 79% for study group and control group respectively in compliance to ISO 15189 and statistically significant difference (P value 0.00) with effect size (Cohen’s d) of (0.00) in pre-intervention phase and (0.99) in post – intervention phase. The annual average cost per-test for the study group and control group was 1.80 ± 0.25 vs. 1.97 ± 0.39, respectively with P value 0.39 whereas the post-intervention results showed that the annual average total costs per-test for study group and control group was 1.57 ± 0.23 vs 2.08 ± 0.38, P value 0.019 respectively, with cost-effectiveness ratio of (0.88) in pre -intervention phase and (0.52) in post-intervention phase. Conclusion: The planned adoption of quality management requirements (QMS) in clinical laboratories had great effect to increase the compliance percent with quality management system requirement, raise the average total cost effectiveness, and improve the analytical process capability of the testing procedure.

HAMZA, Alneil; AHMED-ABAKUR, Eltayib; ABUGROUN, Elsir; BAKHIT, Siham; HOLI, Mohamed

2013-01-01

84

Quality control materials in food composition databanks  

Microsoft Academic Search

Reference materials (RMs) have emerged with the aim of improving analytical methods performance, in what regards to their validation, calibration, uncertainty, training and internal quality control, and of increasing the comparability of measurements between laboratories. Due to their unquestionable importance, but still low availability and high cost, the present work has determined the suitability of infant formula, powdered garlic, tea

I. Castanheira; C. Abrantes; M. Batista; I. Coelho; A. Sanches-Silva

2009-01-01

85

Distance learning applied to control engineering laboratories  

Microsoft Academic Search

Distance learning is an emerging paradigm where students, teachers, and equipment may be at different geographic locations. At the College of Engineering of Oregon State University, we have developed and demonstrated an innovative real-time remote-access control engineering teaching laboratory. Our remote laboratory uses the Internet to provide complete access to the usual laboratory facilities. In addition, remote power control, network

B. Aktan; C. A. Bohus; L. A. Crowl; M. H. Shor

1996-01-01

86

Inter-laboratory comparison of flow-volume curve measurements as quality control procedure in the framework of an international epidemiological study (PEACE project).  

PubMed

The aim of this work was to describe the results of a simple quality control procedure for the flow-volume curve adopted in a multicentre epidemiological study (PEACE). In 14 centres, 8-15 individuals (n = 157) performed forced vital capacity (FVC) manoeuvres following a standard protocol with both the local spirometer/pneumotachograph and a portable spirometer (i.e. the 'reference instrument' for this study). Deviances of measurements were assessed by computing the differences (delta) between the former and the latter, the ratios of such differences on portable spirometer values (delta %) and the coefficients of variation (CV). The portable spirometer yielded lower mean AFVC and deltaFEV1 (forced in 1 sec) than local instruments (except for two and four centres, respectively). In most instances, differences were statistically significant. Absolute mean A%FVC ranged from 4.9-18.2%, while delta%FEV1 ranged from 2.3-18.5%. The Bland and Altman analysis showed a good agreement between the portable and local instruments, except for two centres, where a systematic trend towards higher individual absolute deltaFVC and deltaFEV1 was observed. The overall variability, assessed by CV, was within 6.2% and 5.1% for FVC and FEV1, respectively: it was similar to other quality control studies ranging from 2.0-5.5% for FVC and 2.2-5.8% for FEV1. Our results point out the importance of performing interlaboratory comparisons as a quality control procedure in multicentre epidemiological studies on lung function, and of stimulating manufacturers to extend the accuracy and precision of the instruments. PMID:10783929

Viegi, G; Simoni, M; Pistelli, F; Englert, N; Salonen, R; Niepsuj, G; Haluszk, J; Roeme, W

2000-03-01

87

21 CFR 606.140 - Laboratory controls.  

Code of Federal Regulations, 2011 CFR

... BIOLOGICS CURRENT GOOD MANUFACTURING PRACTICE FOR BLOOD AND BLOOD COMPONENTS Laboratory Controls § 606.140 Laboratory...specifications, standards and test procedures to assure that blood and blood components are safe, pure, potent and...

2011-04-01

88

QUALITY ASSURANCE IN RESEARCH LABORATORIES: RULES AND REASON  

EPA Science Inventory

Quality Assurance in Research Laboratories: Rules and Reason Ron Rogers, Quality Assurance and Records Manager, Environmental Carcinogenesis Division, NHEERL/ORD/US EPA, Research Triangle Park, NC, 27709 To anyone who has actively participated in research, as I have...

89

Implementation of Quality Management in Core Service Laboratories  

PubMed Central

The Genetics and Genomics group of the Advanced Technology Program of SAIC-Frederick exists to bring innovative genomic expertise, tools and analysis to NCI and the scientific community. The Sequencing Facility (SF) provides next generation short read (Illumina) sequencing capacity to investigators using a streamlined production approach. The Laboratory of Molecular Technology (LMT) offers a wide range of genomics core services including microarray expression analysis, miRNA analysis, long read (Roche) next generation sequencing, transgenic genotyping, Sanger sequencing, and clinical mutation detection services to investigators from across the NIH. SF and LMT are working together to bring online the third generation Pacific Bioscience SMRT sequencing platform. As the technology supporting this genomic research becomes more complex, the need for basic quality processes within all aspects of the core service groups becomes critical. The Quality Management group works alongside members of these labs to establish or improve processes supporting operations control (equipment, reagent and materials management), process improvement (reengineering/optimization, automation, acceptance criteria for new technologies and tech transfer), and quality assurance and customer support (controlled documentation/SOPs, training, service deficiencies and continual improvement efforts). Implementation and expansion of quality programs within unregulated environments demonstrates SAIC Frederick's dedication to providing the highest quality products and services to the NIH community.

Creavalle, T.; Dickens, J.; Haque, K.; Raley, C.; Smith, M.W.; Hicks, B.

2011-01-01

90

Implementation of Quality Management in Core Service Laboratories  

PubMed Central

CF-28 The Genetics and Genomics group of the Advanced Technology Program of SAIC-Frederick exists to bring innovative genomic expertise, tools and analysis to NCI and the scientific community. The Sequencing Facility (SF) provides next generation short read (Illumina) sequencing capacity to investigators using a streamlined production approach. The Laboratory of Molecular Technology (LMT) offers a wide range of genomics core services including microarray expression analysis, miRNA analysis, array comparative genome hybridization, long read (Roche) next generation sequencing, quantitative real time PCR, transgenic genotyping, Sanger sequencing, and clinical mutation detection services to investigators from across the NIH. As the technology supporting this genomic research becomes more complex, the need for basic quality processes within all aspects of the core service groups becomes critical. The Quality Management group works alongside members of these labs to establish or improve processes supporting operations control (equipment, reagent and materials management), process improvement (reengineering/optimization, automation, acceptance criteria for new technologies and tech transfer), and quality assurance and customer support (controlled documentation/SOPs, training, service deficiencies and continual improvement efforts). Implementation and expansion of quality programs within unregulated environments demonstrates SAIC-Frederick's dedication to providing the highest quality products and services to the NIH community.

Creavalle, T.; Haque, K.; Raley, C.; Subleski, M.; Smith, M.W.; Hicks, B.

2010-01-01

91

Aerospace Materials Quality Control Presentation  

NSDL National Science Digital Library

This PowerPoint document from the Aerospace Manufacturing Education Project looks into the topic of quality control of materials used in the aerospace industry. The presentation includes 27 slides and covers why quality control is important in this field. It also includes details about aerospace QC teams and techniques, including non-destructive testing.

2012-11-16

92

Computer-assisted quality control in clinical chemistry.  

PubMed

A MUMPS comuter program, which stores and retrieves quality-control data from all automated and manual work-station in the laboratory, has been developed as part of a laboratory information system. Tabular displays, Levey-Jennings charts, and summary statistics are available on a real-time basis. Significant economy over previous manual methods has been observed, and the total quality-control program in the laboratory has become a more active and timely process. PMID:852109

Sher, P P

1977-05-01

93

Quality control programme in mammography: second level quality controls  

Microsoft Academic Search

Mammography is the most reliable method by which to detect lesions in the breast. Since contrast between normal and pathological areas in the breast is extremely low, mammo- graphic image quality should reach high standards without exceeding acceptable exposure levels for the breast. A quality control programme in mammography has been implemented. This programme is subdivided into two levels. The

E NASSIVERA; L NARDIN

94

DEVELOPMENT OF A QUALITY CONTROL DECISION SUPPORT SYSTEM FOR REAL-TIME QUALITY CONTROL OF LIQUID TRANSFER OPERATIONS  

Microsoft Academic Search

Quality control in liquid transfer operations can eliminate false assay results due to transfer failures, monitor the stability of laboratory equipment, provide baselines for continuous improvement, and enable automatic recovery actions for a number of fault conditions. This paper describes the work done to add real-time quality control capability in liquid transfer operations on a closed-loop controlled MEMS based liquid

Hakki Ozgur UNVER; Greg WENDEL; John HOWLAND

95

Quality Control in Digital Mammography  

Microsoft Academic Search

\\u000a An effective quality control system for digital mammography needs to evaluate the status of each stage of image formation\\u000a — acquisition, processing and display. Such quality control benefits greatly from the ability to make more precise and reproducible\\u000a measurements than was possible with film-screen systems. On the other hand, the greater variety of system designs and general\\u000a lack of experience

Kenneth C. Young; Ruben Van Engen; Hilde Bosmans; Jurgen Jacobs; Federica Zanca

96

40 CFR 136.7 - Quality assurance and quality control.  

Code of Federal Regulations, 2012 CFR

...2012-07-01 2012-07-01 false Quality assurance and quality control. 136.7 Section...PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) GUIDELINES...ANALYSIS OF POLLUTANTS § 136.7 Quality assurance and quality...

2012-07-01

97

Clay-liner construction and quality control  

Microsoft Academic Search

Soil handling and liner-construction practices at hazardous-waste-management facilities are documented. Soil characterizations, processing techniques, construction methods, and quality control of constructed liners are reviewed and compared. Results indicate widely different testing and construction methods at 23 facilities nationwide. Laboratory research indicates that selected clay soils exhibit low hydraulic conductivity to water and certain non-water liquid wastes. This characteristic makes clay

J. Jeffrey Peirce; Goran Sallfors; Eric Peterson

1986-01-01

98

Quality control for registry HLA data.  

PubMed

In this panel discussion, the following issues were addressed: the evaluation of the quality of the volunteer donors human leukocyte antigen (HLA) assignments, the quality criteria that should be met by the laboratories, the source of errors, the measures that registries can take to assess the quality of HLA testing, and the updating of the initial result with emphasis on resolution of typing discrepancies. Several relevant factors were put forward: the need for the registries to define the HLA loci and the level of resolution requested, and the importance of the accreditation programs with adequate external proficiency testing. The feasibility of annual quality controls of a national registry addressing the limitations of HLA class I serology, and the rules set up by a large registry to incorporate new data on donors HLA types and to rapidly track typing discrepancies, were reported. PMID:17445155

Tiercy, J-M; Fischer, G; Setterholm, M

2007-04-01

99

222-S Laboratory Quality Assurance Plan. Revision 1  

Microsoft Academic Search

This Quality Assurance Plan provides,quality assurance (QA) guidance, regulatory QA requirements (e.g., 10 CFR 830.120), and quality control (QC) specifications for analytical service. This document follows the U.S Department of Energy (DOE) issued Hanford Analytical Services Quality Assurance Plan (HASQAP). In addition, this document meets the objectives of the Quality Assurance Program provided in the WHC-CM-4-2, Section 2.1. Quality assurance

Meznarich

1995-01-01

100

40 CFR 136.7 - Quality assurance and quality control.  

Code of Federal Regulations, 2013 CFR

... (ii) Method Detection Limit (MDL); (iii) Laboratory reagent blank (LRB), also referred to as method blank (MB); (iv) Laboratory fortified blank (LFB), also referred to as a spiked blank, or laboratory control...

2013-07-01

101

Alkylation reactor quality control  

SciTech Connect

This patent describes an apparatus comprising: an alkylation reactor; a fractional distillation column means; means for withdrawing a mixture containing unreacted isoparaffin as a reactor effluent stream from the alkylation reactor, and for providing the reactor effluent stream as a feed to the fractional distillation column means wherein at least a portion of the unreacted isoparaffin is separated to form a predominantly isoparaffin containing recycle stream; means for combining an isoparaffin-containing fluid stream with an olefin-containing fluid stream to form a combined isoparaffin and olefin stream; means for combining the recycle stream and the combined paraffin and olefin stream to form a combined feed stream and for providing the combined feed stream to the alkylation reactor; means for establishing a first signal representative of the desired isoparaffin-to-olefin ratio in the combined feed stream; means for establishing a second signal representative of the flow rate of the combined feed stream; means for establishing a third signal representative of the flow rate of the isoparaffin-containing fluid stream; means for establishing a fourth signal representative of the flow rate of the reactor effluent stream; analyzer means for detecting the concentration of olefin supplied through the combined feed stream; and for detecting the concentration of isoparaffin supplied through the combined feed stream, and for detecting the molecular weight of the combined feed stream; computer means responsive to the analyzer means and to the first, second, third and fourth signals; means for manipulating the flow rate of the isoparaffin containing fluid stream in response to the first control signal, means for manipulating the flow rate of the reactor effluent stream in response to the second control signal, to thereby maintain the liquid level in the alkylation reactor essentially constant.

Funk, G.L.; Bard, W.B.

1987-12-15

102

Quality Control and Processing of Historical Oceanographic Nutrient Data.  

National Technical Information Service (NTIS)

This paper is a description of the procedures used by the Ocean Climate Laboratory (OCL) in the quality control of the historical oceanographic nutrient data archived at the National Oceanographic Data Center (NODC). These procedures involve: (1) range ch...

M. E. Conkright T. P. Boyer S. Levitus

1994-01-01

103

Development of Suspended Solids Quality Control and Performance Evaluation Samples.  

National Technical Information Service (NTIS)

A two phase study was conducted to develop a synthetic suspended solids sample for use as quality control check and performance evaluation within environmental monitoring laboratories. The first phase consisted of a feasibility study to determine compound...

E. L. Stover P. J. Marks

1976-01-01

104

Safety in the Chemical Laboratory: Flood Control.  

ERIC Educational Resources Information Center

|Describes events leading to a flood in the Wehr Chemistry Laboratory at Marquette University, discussing steps taken to minimize damage upon discovery. Analyzes the problem of flooding in the chemical laboratory and outlines seven steps of flood control: prevention; minimization; early detection; stopping the flood; evaluation; clean-up; and…

Pollard, Bruce D.

1983-01-01

105

Power Supplies for Space Systems Quality Assurance by Sandia Laboratories.  

National Technical Information Service (NTIS)

The Sandia Laboratories' participation in Quality Assurance programs for Radioisotopic Thermoelectric Generators which have been used in space systems over the past 10 years is summarized. Basic elements of this QA program are briefly described and recogn...

R. L. Hannigan R. R. Harnar

1976-01-01

106

Laboratory use of industrial control systems  

Microsoft Academic Search

Industrial control system manufacturers supply the building blocks for the control of industrial equipment or specific process control applications. Although the laboratory environment is different in many aspects (prototyping, evolution and frequent reconfiguration), the use of these building blocks remain attractive because of their general purpose nature, their cost and the large spectrum of available types. In this paper we

A. Rijllart; L. Avot; D. Brahy; D. Jégou; R. Saban

1994-01-01

107

Controlled Atmosphere System Laboratory Studies on Tomatoes.  

National Technical Information Service (NTIS)

Laboratory tests were conducted to determine the effect of low-oxygen controlled atmosphere (which is carbon dioxide free) on tomatoes. Storage periods approximating the extended overseas distribution time of 3 to 8 weeks as required for military shipment...

H. Gorfien A. R. Rahman G. Taylor D. E. Westcott

1970-01-01

108

Quality management in hematology laboratory improved preanalytics variables  

Microsoft Academic Search

Clinical decisions based on laboratory test values are correctly made when a preanalytical stage is properly performed. In this study we demonstrated that introduction of quality management procedures to Hematology laboratory at Medical Center and Health Care Center have helped to solve problems in the preanalytic stage. Blood clotting is a highly complicated process, which begins during blood withdrawal from

Galit Sarig; Bilha Albersheim; Tamar Stam; Ruth Beck; Naomi Lanir

2003-01-01

109

Product Quality Control Based on Collaborative Controller  

Microsoft Academic Search

In the network manufacture, the difficulties and complications of remote quality control come from a lot of factors such as the complication of system, the multiplicity of the products, and the extensiveness of information and the higher requirements of the clients especially the different manufacture source of the parts, materials, equipments, processes, industrial standards, and the difference of the operators'

Yang Musheng; Zhang Yu; Li Aijun

2009-01-01

110

21 CFR 226.58 - Laboratory controls.  

Code of Federal Regulations, 2010 CFR

...CONTINUED) DRUGS: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR TYPE A MEDICATED ARTICLES Product Quality Control...and the Type A medicated article(s) conform to appropriate...manufacture of Type A medicated article(s). This may...

2010-04-01

111

21 CFR 226.58 - Laboratory controls.  

Code of Federal Regulations, 2010 CFR

...CONTINUED) DRUGS: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR TYPE A MEDICATED ARTICLES Product Quality Control...and the Type A medicated article(s) conform to appropriate...manufacture of Type A medicated article(s). This may...

2009-04-01

112

New laboratory tools in the assessment of bone quality  

Microsoft Academic Search

Bone quality is a complex set of intricated and interdependent factors that influence bone strength. A number of methods have\\u000a emerged to measure bone quality, taking into account the organic or the mineral phase of the bone matrix, in the laboratory.\\u000a Bone quality is a complex set of different factors that are interdependent. The bone matrix organization can be described

D. Chappard; M. F. Baslé; E. Legrand; M. Audran

2011-01-01

113

7 CFR 930.44 - Quality control.  

Code of Federal Regulations, 2013 CFR

...VEGETABLES, NUTS), DEPARTMENT OF AGRICULTURE TART CHERRIES GROWN IN THE STATES OF MICHIGAN, NEW YORK, PENNSYLVANIA, OREGON, UTAH, WASHINGTON, AND WISCONSIN Order Regulating Handling Quality Control § 930.44 Quality control. (a) Quality...

2013-01-01

114

Earned quality: improving project control  

Microsoft Academic Search

The concept of earned value has been widely used in project management to measure and control the achievement of time and cost objectives. However, no such equivalent concept has ever been devised to assess and monitor the quality of a project. The goal of the paper is to propose a multiattribute utility theory approach that enables project managers to measure

J. P. Paquin; J. Couillard; R. Paquin; D. Godcharles

1996-01-01

115

Laboratory cost control and financial management software  

Microsoft Academic Search

Economical constraints within the health care system advocate the introduction of tighter control of costs in clinical laboratories. Detailed cost information forms the basis for cost control and financial management. Based on the cost information, proper decisions regarding priorities, procedure choices, personnel policies and investments can be made. This presentation outlines some principles of cost analysis, describes common limitations of

Michael Mayer

1998-01-01

116

Quality Assurance\\/Quality Control (QA\\/QC) regime in marine pollution monitoring programmes: The GIPME perspective  

Microsoft Academic Search

A fundamental requirement in collaborative monitoring programmes in marine pollution studies is the intercomparability of data obtained from participating laboratories irrespective of the country of origin. This demands that the data be ‘true’. The production of ‘true’ data requires that laboratories adopt good field and laboratory procedures as part and parcel of a Quality Assurance\\/Quality Control (QA\\/QC) regime. This includes

A. Chidi Ibe; Gunnar Kullenberg

1995-01-01

117

Approaches to quality management and accreditation in a genetic testing laboratory  

PubMed Central

Medical laboratories, and specifically genetic testing laboratories, provide vital medical services to different clients: clinicians requesting a test, patients from whom the sample was collected, public health and medical-legal instances, referral laboratories and authoritative bodies. All expect results that are accurate and obtained in an efficient and effective manner, within a suitable time frame and at acceptable cost. There are different ways of achieving the end results, but compliance with International Organization for Standardization (ISO) 15189, the international standard for the accreditation of medical laboratories, is becoming progressively accepted as the optimal approach to assuring quality in medical testing. We present recommendations and strategies designed to aid genetic testing laboratories with the implementation of a quality management system, including key aspects such as document control, external quality assessment, internal quality control, internal audit, management review, validation, as well as managing the human side of change. The focus is on pragmatic approaches to attain the levels of quality management and quality assurance required for accreditation according to ISO 15189, within the context of genetic testing. Attention is also given to implementing efficient and effective quality improvement.

Berwouts, Sarah; Morris, Michael A; Dequeker, Elisabeth

2010-01-01

118

Air quality management in the WHO European Region — Results of a quality assurance and control programme on air quality monitoring (1994–2004)  

Microsoft Academic Search

Since the last decade the WHO Collaborating Centre for Air Quality Management and Air Pollution Control, Berlin, Germany, operates a quality assurance and control (QA\\/QC) programme on air quality monitoring in the WHO European Region. As main activity Intercomparison workshops have been established for air monitoring network laboratories on a regular basis to harmonise air quality measurements, analysis and calibration

Hans-Guido Mücke

2008-01-01

119

Quality control in immunocytochemistry: experiences with the oestrogen receptor assay  

Microsoft Academic Search

AIMS: To evaluate the feasibility of an interlaboratory quality control programme in immunohistochemistry. METHODS: Several pathology laboratories were asked to carry out immunohistochemical oestrogen receptor staining on a set of freeze dried cryostat sections of breast cancer tissue. The sections and protocols for staining and semi-quantitative scoring were mailed to the participating laboratories in two trials. The oestrogen receptor content

F T Bosman; A F de Goeij; M Rousch

1992-01-01

120

QUALITY ASSURRANCE AND THE USE OF A REFERENCE LABORATORY  

Microsoft Academic Search

1. QA\\/QC Air quality monitoring must satisfy certain minimum quality requirements and standards. Measurements, regardless of where and by whom they are carried out, must be comparable to those conducted elsewhere. This is secured through a comprehensive Quality Assurance and Quality Control programme (QA\\/QC). QA\\/QC may be regarded as a chain of activities designed to deliver credible and accurate data.

Bjarne SIVERTSEN

121

Total Quality Management at an Oak Ridge laboratory and the establishment of an internal quality program  

SciTech Connect

In order for any laboratory to be successful today, it is imperative that a total commitment to quality management be the keystone of that laboratory. Modern industry has begun to recognize that it must reach beyond traditional Quality Assurance methods and enlist the participation of all members of the organization for their unique contributions to make their organizations truly excellent. This report discusses Total Quality Management in the Analytical Services Organization at Oak Ridge, Tennessee. Laboratories are in the Y-12 Plant, which is one of three government sites located in Oak Ridge that are managed by Martin Marietta Energy Systems for the Department of Energy (DOE).

Dorsey, J.G.

1993-11-01

122

A Laboratory Testbed for Embedded Fuzzy Control  

ERIC Educational Resources Information Center

|This paper presents a novel scheme called "Laboratory Testbed for Embedded Fuzzy Control of a Real Time Nonlinear System." The idea is based upon the fact that project-based learning motivates students to learn actively and to use their engineering skills acquired in their previous years of study. It also fosters initiative and focuses students'…

Srivastava, S.; Sukumar, V.; Bhasin, P. S.; Arun Kumar, D.

2011-01-01

123

Laboratory facility for flexible structure control experiments  

Microsoft Academic Search

A laboratory facility to study various control problems related to flexible mechanical structures is described. Computer, interfacing, and software issues are discussed. A novel proof-mass actuator is presented. A free-free suspended-beam experiment and a skewing-beam experiment are described. Three additional experimental setups at various stages of development are briefly considered

Umit OzgUner; Stephen Yurkovich; Joseph W. Martin; Paul T. Kotnik

1988-01-01

124

Is Serological Testing a Reliable Tool in Laboratory Diagnosis of Syphilis? Meta-Analysis of Eight External Quality Control Surveys Performed by the German Infection Serology Proficiency Testing Program  

PubMed Central

The accuracy of diagnostic tests is critical for successful control of epidemic outbreaks of syphilis. The reliability of syphilis serology in the nonspecialist laboratory has always been questioned, but actual data dealing with this issue are sparse. Here, the results of eight proficiency testing sentinel surveys for diagnostic laboratories in Germany between 2000 and 2003 were analyzed. Screening tests such as Treponema pallidum hemagglutination assay (mean accuracy, 91.4% [qualitative], 75.4% [quantitative]), Treponema pallidum particle agglutination assay (mean accuracy, 98.1% [qualitative], 82.9% [quantitative]), and enzyme-linked immunosorbent assays (ELISAs) (mean qualitative accuracy, 95%) were more reliable than Venereal Disease Research Laboratory (VDRL) testing (mean accuracy, 89.6% [qualitative], 71.1% [quantitative]), the fluorescent treponemal antibody absorption test (FTA-ABS) (mean accuracy, 88% [qualitative], 65.8% [quantitative]), and immunoblot assays (mean qualitative accuracy, 87.3%). Clearly, immunoglobulin M (IgM) tests were more difficult to manage than IgG tests. False-negative results for samples that have been unambiguously determined to be IgM and anti-lipoid antibody positive accounted for 4.7% of results in the IgM ELISA, 6.9% in the VDRL test, 18.5% in the IgM FTA-ABS, and 23.0% in the IgM immunoblot assay. For negative samples, the mean percentage of false-positive results was 4.1% in the VDRL test, 5.4% in the IgM ELISA, 0.7% in the IgM FTA-ABS, and 1.4% in the IgM immunoblot assay. On average, 18.3% of participants misclassified samples from patients with active syphilis as past infection without indicating the need for further treatment. Moreover, 10.2% of laboratories wrongly reported serological evidence for active infection in samples from patients with past syphilis or in sera from seronegative blood donors. Consequently, the continuous participation of laboratories in proficiency testing and further standardization of tests is strongly recommended to achieve better quality of syphilis serology.

Muller, Iris; Brade, Volker; Hagedorn, Hans-Jochen; Straube, Erich; Schorner, Christoph; Frosch, Matthias; Hlobil, Harald; Stanek, Gerold; Hunfeld, Klaus-Peter

2006-01-01

125

Control of Spacecraft Control Laboratory Experiment (SCOLE) Slew Maneuvers.  

National Technical Information Service (NTIS)

This is the second report of a set of two reports on the dynamics and control of slewing maneuvers of NASA Spacecraft Control Laboratory Experiment (SCOLE). The control problem of slewing maneuvers of SCOLE is developed in terms of an arbitrary maneuver a...

Y. P. Kakad

1987-01-01

126

Testing a Constrained MPC Controller in a Process Control Laboratory  

ERIC Educational Resources Information Center

This paper describes an experiment performed by the fourth year chemical engineering students in the process control laboratory at the University of Waterloo. The objective of this experiment is to test the capabilities of a constrained Model Predictive Controller (MPC) to control the operation of a Double Pipe Heat Exchanger (DPHE) in real time.…

Ricardez-Sandoval, Luis A.; Blankespoor, Wesley; Budman, Hector M.

2010-01-01

127

Testing a Constrained MPC Controller in a Process Control Laboratory  

ERIC Educational Resources Information Center

|This paper describes an experiment performed by the fourth year chemical engineering students in the process control laboratory at the University of Waterloo. The objective of this experiment is to test the capabilities of a constrained Model Predictive Controller (MPC) to control the operation of a Double Pipe Heat Exchanger (DPHE) in real time.…

Ricardez-Sandoval, Luis A.; Blankespoor, Wesley; Budman, Hector M.

2010-01-01

128

Towards constructivist laboratory education: Case study for process control laboratory  

Microsoft Academic Search

Laboratory education is an integrated part of engineering and science degrees. Many research papers refer to poor constructivist learning during the laboratory sessions, indicating the need for reforming the laboratory education in a way that facilitates constructivist learning as well as conceptual understanding. In this paper we present a model of conducting laboratories, based on the well known Kolbpsilas experiential

Mahmoud Abdulwahed; Zoltan K Nagy

2008-01-01

129

Developing a quality plan at a national laboratory  

SciTech Connect

Los Alamos National Laboratory has recently begun to develop a Laboratory-wide quality program. The author discusses in this talk some of the reasons that have caused many of the Laboratory staff to oppose the introduction of formal quality assurance (QA) programs. In analyzing these reasons, it is found that many of the elements of a good quality program are, in fact, already in use. However, a perception still exists that formal QA is an unnecessary bureaucratic burden. There is fear that the freedom of action essential to a good research and development laboratory will be restricted under a QA program. To address this valid concern, the author proposes that we need to re-examine the real purpose of QA, and suggests a new working definition of the term that may be more readily applicable to a multidisciplinary research and development laboratory. It is clear that we cannot successfully promote useful and effective QA programs unless we are willing to broaden our view and be more flexible in our applications of QA methodologies. The author will report on the results of their approach over the first year. We know that much of our task will be to persuade a skeptical staff that a quality program, thoughtfully prepared and properly used, can be a means not only for maintaining our reputation for excellence but also for systematically re-evaluating and improving the way we do our work. We are hopeful that the Laboratory Quality Plan will provide an effective first step toward that goal. 2 refs.

Davis, A.H.

1988-01-01

130

Cross-infection control in dental laboratories.  

PubMed

The attitudes to cross-infection control of 800 dental laboratories registered with the Dental Laboratories Association have been surveyed. Considering the topicality of the subject material and the need for careful cross-infection control within and beyond the dental surgery, the response rate of 22% (175) was disappointingly low. As a result of the low response rate, the results should be seen as a guide only. Forty-nine percent of respondents had a cross-infection policy and of those with no policy 64% intended to implement one in the future. Thirty percent of laboratories receive known undisinfected work from the dental surgery. Of those items disinfected on arrival at the laboratory, those most frequently disinfected are dental impressions (77%) and dentures (51%). The most popular chemicals used for disinfection are household bleach, chlorhexidine and glutaraldehyde. Forty-four percent of the respondents generally (90% or more of the time) wear gloves when handling dental work received and opened in the laboratory. Seventy-four percent wear protective eye spectacles when trimming or polishing prostheses. Sixty-one percent used no disinfectant in the pumice and 93% did not disinfect the polishing instruments, eg wheels and mops. Forty-six percent had a policy for immunisation of staff against Hepatitis B. PMID:7546949

Jagger, D C; Huggett, R; Harrison, A

1995-08-01

131

30 CFR 74.6 - Quality control.  

Code of Federal Regulations, 2011 CFR

...be sampled and tested to maintain its quality prior to assembly of each sampler unit. In order to assure that the quality of the CMDPSU will be maintained in production through adequate quality control procedures, MSHA and NIOSH...

2013-07-01

132

Quality management systems for your in vitro fertilization clinic's laboratory: Why bother?  

PubMed Central

Several countries have in recent years introduced prescribed requirements for treatment and monitoring of outcomes, as well as a licensing or accreditation requirement for in vitro fertilization (IVF) clinics and their laboratories. It is commonplace for Assisted Reproductive Technology (ART) laboratories to be required to have a quality control system. However, more effective Total Quality Management systems are now being implemented by an increasing number of ART clinics. In India, it is now a requirement to have a quality management system in order to be accredited and to help meet customer demand for improved delivery of ART services. This review contains the proceedings a quality management session at the Indian Fertility Experts Meet (IFEM) 2010 and focuses on the creation of a patient-oriented best-in-class IVF laboratory.

Olofsson, Jan I; Banker, Manish R; Sjoblom, Late Peter

2013-01-01

133

Quality assurance in the HIV/AIDS laboratory network of China  

PubMed Central

Background In 2009, there were 8273 local screening laboratories, 254 confirmatory laboratories, 35 provincial confirmatory central laboratories and 1 National AIDS Reference Laboratory (NARL) in China. These laboratories were located in Center for Disease Control and Prevention (CDC) facilities, hospitals, blood donation clinics, maternal and child health (MCH) hospitals and border health quarantine health-care facilities. Methods The NARL and provincial laboratories provide quality assurance through technical, bio-safety and managerial training; periodic proficiency testing; on-site supervisory inspections; and commercial serologic kit evaluations. Results From 2002 to 2009, more than 220 million HIV antibody tests were performed at screening laboratories, and all reactive and indeterminate samples were confirmed at confirmatory laboratories. The use of highly technically complex tests, including CD4 cell enumeration, viral load, dried blood spot (DBS)-based early infant diagnosis (EID), drug resistance (DR) genotyping, HIV-1 subtyping and incidence assays, have increased in recent years and their performance quality is closely monitored. Conclusion China has made significant progress in establishing a well-coordinated HIV laboratory network and QA systems. However, the coverage and intensity of HIV testing and quality assurance programmes need to be strengthened so as to ensure that more infected persons are diagnosed and that they receive timely prevention and treatment services.

Jiang, Yan; Qiu, Maofeng; Zhang, Guiyun; Xing, Wenge; Xiao, Yao; Pan, Pinliang; Yao, Jun; Ou, Chin-Yih; Su, Xueli

2010-01-01

134

Blind quality control samples: Which radionuclides, what activity levels?  

Microsoft Academic Search

Since today`s radioanalytical laboratory spends a significant amount of time analyzing quality control (QC) samples, it is important to design an efficient measurements quality-assurance (QA) program. Two important considerations when designing or evaluating a blind, QC sample-analysis program are which radionuclides and what activities should be used to evaluate the quality of measurements. If the radionuclides are not chosen carefully,

McFarland

1995-01-01

135

Power supplies for space systems quality assurance by Sandia Laboratories  

Microsoft Academic Search

The Sandia Laboratories' participation in Quality Assurance programs for Radioisotopic Thermoelectric Generators which have been used in space systems over the past 10 years is summarized. Basic elements of this QA program are briefly described and recognition of assistance from other Sandia organizations is included. Descriptions of the various systems for which Sandia has had the QA responsibility are presented,

R. L. Hannigan; R. R. Harnar

1976-01-01

136

USDA, ARS Soft Wheat Quality Laboratory, Annual Report 2011  

Technology Transfer Automated Retrieval System (TEKTRAN)

The report describes new activities for the lab including the a transitions in the laboratory and activites on the USDA, NIFA-funded Triticeae CAP project. Recent research on milling and quality evaluations, data management, molecular evaluations, stem rust resistance from the lab are highlighted, ...

137

Quality Assurance at Sandia Laboratories. [Nuclear weapons materials  

Microsoft Academic Search

The publication describes the Sandia Laboratories Quality Assurance (QA) program, its role with the Albuquerque Operations Office of the Department of Energy (DOE\\/ALO) in achieving the stringent safety and reliability goals which have been established for weapon material, and its expanding role in national security, energy, and other programs of national importance.

S. L. Love; F. W. Muller

1978-01-01

138

Analytical Chemistry Laboratory Quality Assurance Project Plan for the Transuranic Waste Characterization Program  

SciTech Connect

This Quality Assurance Project Plan (QAPJP) specifies the quality of data necessary and the characterization techniques employed at the Idaho National Engineering Laboratory (INEL) to meet the objectives of the Department of Energy (DOE) Waste Isolation Pilot Plant (WIPP) Transuranic Waste Characterization Quality Assurance Program Plan (QAPP) requirements. This QAPJP is written to conform with the requirements and guidelines specified in the QAPP and the associated documents referenced in the QAPP. This QAPJP is one of a set of five interrelated QAPjPs that describe the INEL Transuranic Waste Characterization Program (TWCP). Each of the five facilities participating in the TWCP has a QAPJP that describes the activities applicable to that particular facility. This QAPJP describes the roles and responsibilities of the Idaho Chemical Processing Plant (ICPP) Analytical Chemistry Laboratory (ACL) in the TWCP. Data quality objectives and quality assurance objectives are explained. Sample analysis procedures and associated quality assurance measures are also addressed; these include: sample chain of custody; data validation; usability and reporting; documentation and records; audits and 0385 assessments; laboratory QC samples; and instrument testing, inspection, maintenance and calibration. Finally, administrative quality control measures, such as document control, control of nonconformances, variances and QA status reporting are described.

Sailer, S.J.

1996-08-01

139

Proactive quality paint thickness control using ANFIS  

Microsoft Academic Search

Automotive industries try to develop their technologies to improve quality and to minimize scrapes and wastes. In the paint shop vehicle, quality control generally relies on inspection. Industries try to develop their technologies to improve quality via proactive quality control. This paper investigates the predictability of the paint thickness to reduce defects, using ANFIS. A description of the automobile paint

Reza Radfar; Javad J. Jassbi; Felora Ghoreishi; Sohrab Khanmohammadi; Mahmood Alborzi

2010-01-01

140

Quality management in environmental programs: Los Alamos National Laboratory`s approach  

SciTech Connect

Since its inception in 1943, Los Alamos National Laboratory`s (LANL`s) primary mission has been nuclear weapons research and development, which involved the use of hazardous and radioactive materials, some of which were disposed of onsite. LANL has established an extensive Environmental Restoration Project (Project) to investigate and remediate those hazardous and radioactive waste disposal sites. This paper describes LANL`s identification and resolution of critical issues associated with the integration and management of quality in the Project.

Maassen, L.; Day, J.L.

1998-03-01

141

Quality control and testing of optical instruments  

NASA Astrophysics Data System (ADS)

The quality control and testing of optical instruments are examined from both theoretical and practical standpoints. In particular, attention is given to methods for determining the differential and complex quality characteristics of optical instruments and their subsystems, service conditions of optical instruments, metrological aspects of quality control and testing, and organizational aspects and the efficiency of quality control and testing. Other topics discussed including control, testing, and adjustment equipment; methods for testing optical instruments during assembly; and classification of tests and testing techniques.

Petrov, V. P.

142

Quality Assurance of RNA Expression Profiling in Clinical Laboratories  

Microsoft Academic Search

RNA expression profiles are increasingly used to diagnose and classify disease, based on expression patterns of as many as several thousand RNAs. To assure quality of expression profiling services in clinical settings, a standard operating procedure incorporates multiple quality indicators and controls, beginning with preanalytic specimen preparation and proceeding through analysis, interpretation, and reporting. Before testing, histopathologic examination of each

Weihua Tang; Zhiyuan Hu; Hind Muallem; Margaret L. Gulley

143

Transaction processing in a quality control laboratory.  

National Technical Information Service (NTIS)

Sample receiving data is received from VAX 8700 process computer via Ethernet and saved in RDB database on VAX 11/750 lab computer for transmission of results. Data entry pretests include technician qualification and instrument verification by analysis of...

J. E. Aull

1990-01-01

144

Transaction processing in a quality control laboratory  

SciTech Connect

Sample receiving data is received from VAX 8700 process computer via Ethernet and saved in RDB database on VAX 11/750 lab computer for transmission of results. Data entry pretests include technician qualification and instrument verification by analysis of blind standards. Raw data are transmitted by instruments that talk to ADACS 1200 systems via microprocessors to lab computer which confirms storage to instrument operator. Results are transmitted to process computer by batch job submitted by approving supervisor. Results are archived as samples are disposed. Daily reports of sample load and results are printed. Weekly reports of technician qualification are printed. Scientist and managers retrieve results, sample status, and technician qualification reports via heirarchical menu system. 13 figs.

Aull, J.E.

1990-01-01

145

New laboratory tools in the assessment of bone quality.  

PubMed

Bone quality is a complex set of intricated and interdependent factors that influence bone strength. A number of methods have emerged to measure bone quality, taking into account the organic or the mineral phase of the bone matrix, in the laboratory. Bone quality is a complex set of different factors that are interdependent. The bone matrix organization can be described at five different levels of anatomical organization: nature (organic and mineral), texture (woven or lamellar), structure (osteons in the cortices and arch-like packets in trabecular bone), microarchitecture, and macroarchitecture. Any change in one of these levels can alter bone quality. An altered bone remodeling can affect bone quality by influencing one or more of these factors. We have reviewed here the main methods that can be used in the laboratory to explore bone quality on bone samples. Bone remodeling can be evaluated by histomorphometry; microarchitecture is explored in 2D on histological sections and in 3D by microCT or synchrotron. Microradiography and scanning electron microscopy in the backscattered electron mode can measure the mineral distribution; Raman and Fourier-transformed infra-red spectroscopy and imaging can simultaneously explore the organic and mineral phase of the matrix on multispectral images; scanning acoustic microscopy and nanoindentation provide biomechanical information on individual trabeculae. Finally, some histological methods (polarization, surface staining, fluorescence, osteocyte staining) may also be of interest in the understanding of quality as a component of bone fragility. A growing number of laboratory techniques are now available. Some of them have been described many years ago and can find a new youth; others having benefited from improvements in physical and computer techniques are now available. PMID:21347743

Chappard, D; Baslé, M F; Legrand, E; Audran, M

2011-02-24

146

[Quality control of laser imagers].  

PubMed

Multiformat imagers based on laser systems are used for documentation in an increasing number of investigations. The specific problems of quality control are explained and the persistence of film processing in these imager systems of different configuration with (Machine 1: 3M-Laser-Imager-Plus M952 with connected 3M Film-Processor, 3M-Film IRB, X-Rax Chemical Mixer 3M-XPM, 3M-Developer and Fixer) or without (Machine 2: 3M-Laser-Imager-Plus M952 with separate DuPont-Cronex Film-processor, Kodak IR-Film, Kodak Automixer, Kodak-Developer and Fixer) connected film processing unit are investigated. In our checking based on DIN 6868 and ONORM S 5240 we found persistence of film processing in the equipment with directly adapted film processing unit according to DIN and ONORM. The checking of film persistence as demanded by DIN 6868 in these equipment could therefore be performed in longer periods. Systems with conventional darkroom processing comparatively show plain increased fluctuation, and hence the demanded daily control is essential to guarantee appropriate reaction and constant quality of documentation. PMID:1457474

Winkelbauer, F; Ammann, M; Gerstner, N; Imhof, H

1992-11-01

147

Los Alamos National Laboratory Yucca Mountain Site Characterization Project 1994 quality program status report  

SciTech Connect

This status report is for calendar year 1994. It summarizes the annual activities and accomplishments of the Los Alamos National Laboratory Yucca Mountain Site Characterization Project (YMP or Project) quality assurance program. By identifying the accomplishments of the quality program, a baseline is established that will assist in decision making, improve administrative controls and predictability, and allow us to annually identify adverse trends and to evaluate improvements. This is the fourth annual status report.

Bolivar, S.L.

1996-03-01

148

Laboratory cost control and financial management software.  

PubMed

Economical constraints within the health care system advocate the introduction of tighter control of costs in clinical laboratories. Detailed cost information forms the basis for cost control and financial management. Based on the cost information, proper decisions regarding priorities, procedure choices, personnel policies and investments can be made. This presentation outlines some principles of cost analysis, describes common limitations of cost analysis, and exemplifies use of software to achieve optimized cost control. One commercially available cost analysis software, LabCost, is described in some detail. In addition to provision of cost information, LabCost also serves as a general management tool for resource handling, accounting, inventory management and billing. The application of LabCost in the selection process of a new high throughput analyzer for a large clinical chemistry service is taken as an example for decisions that can be assisted by cost evaluation. It is concluded that laboratory management that wisely utilizes cost analysis to support the decision-making process will undoubtedly have a clear advantage over those laboratories that fail to employ cost considerations to guide their actions. PMID:9541753

Mayer, M

1998-02-01

149

Gradient algorithm applied to laboratory quantum control  

SciTech Connect

The exploration of a quantum control landscape, which is the physical observable as a function of the control variables, is fundamental for understanding the ability to perform observable optimization in the laboratory. For high control variable dimensions, trajectory-based methods provide a means for performing such systematic explorations by exploiting the measured gradient of the observable with respect to the control variables. This paper presents a practical, robust, easily implemented statistical method for obtaining the gradient on a general quantum control landscape in the presence of noise. In order to demonstrate the method's utility, the experimentally measured gradient is utilized as input in steepest-ascent trajectories on the landscapes of three model quantum control problems: spectrally filtered and integrated second harmonic generation as well as excitation of atomic rubidium. The gradient algorithm achieves efficiency gains of up to approximately three times that of the standard genetic algorithm and, as such, is a promising tool for meeting quantum control optimization goals as well as landscape analyses. The landscape trajectories directed by the gradient should aid in the continued investigation and understanding of controlled quantum phenomena.

Roslund, Jonathan; Rabitz, Herschel [Department of Chemistry, Princeton University, Princeton, New Jersey 08544 (United States)

2009-05-15

150

Quality Control by Artificial Vision  

SciTech Connect

Computational technology has fundamentally changed many aspects of our lives. One clear evidence is the development of artificial-vision systems, which have effectively automated many manual tasks ranging from quality inspection to quantitative assessment. In many cases, these machine-vision systems are even preferred over manual ones due to their repeatability and high precision. Such advantages come from significant research efforts in advancing sensor technology, illumination, computational hardware, and image-processing algorithms. Similar to the Special Section on Quality Control by Artificial Vision published two years ago in Volume 17, Issue 3 of the Journal of Electronic Imaging, the present one invited papers relevant to fundamental technology improvements to foster quality control by artificial vision, and fine-tuned the technology for specific applications. We aim to balance both theoretical and applied work pertinent to this special section theme. Consequently, we have seven high-quality papers resulting from the stringent peer-reviewing process in place at the Journal of Electronic Imaging. Some of the papers contain extended treatment of the authors work presented at the SPIE Image Processing: Machine Vision Applications conference and the International Conference on Quality Control by Artificial Vision. On the broad application side, Liu et al. propose an unsupervised texture image segmentation scheme. Using a multilayer data condensation spectral clustering algorithm together with wavelet transform, they demonstrate the effectiveness of their approach on both texture and synthetic aperture radar images. A problem related to image segmentation is image extraction. For this, O'Leary et al. investigate the theory of polynomial moments and show how these moments can be compared to classical filters. They also show how to use the discrete polynomial-basis functions for the extraction of 3-D embossed digits, demonstrating superiority over Fourier-basis functions for this task. Image registration is another important task for machine vision. Bingham and Arrowood investigate the implementation and results in applying Fourier phase matching for projection registration, with a particular focus on nondestructive testing using computed tomography. Readers interested in enriching their arsenal of image-processing algorithms for machine-vision tasks should find these papers enriching. Meanwhile, we have four papers dealing with more specific machine-vision tasks. The first one, Yahiaoui et al., is quantitative in nature, using machine vision for real-time passenger counting. Occulsion is a common problem in counting objects and people, and they circumvent this issue with a dense stereovision system, achieving 97 to 99% accuracy in their tests. On the other hand, the second paper by Oswald-Tranta et al. focuses on thermographic crack detection. An infrared camera is used to detect inhomogeneities, which may indicate surface cracks. They describe the various steps in developing fully automated testing equipment aimed at a high throughput. Another paper describing an inspection system is Molleda et al., which handles flatness inspection of rolled products. They employ optical-laser triangulation and 3-D surface reconstruction for this task, showing how these can be achieved in real time. Last but not least, Presles et al. propose a way to monitor the particle-size distribution of batch crystallization processes. This is achieved through a new in situ imaging probe and image-analysis methods. While it is unlikely any reader may be working on these four specific problems at the same time, we are confident that readers will find these papers inspiring and potentially helpful to their own machine-vision system developments.

Lam, Edmond Y. [University of Hong Kong, The; Gleason, Shaun Scott [ORNL; Niel, Kurt S. [Upper Austria University of Applied Science, Engineering and Environmental Studies

2010-01-01

151

Quality Control Monitoring for WFCAM  

NASA Astrophysics Data System (ADS)

We present the data Quality Control (QC) infrastructure that has been put in place at the Cambridge Astronomical Survey Unit (CASU) to deal with the large data volume produced by WFCAM. QC measures are produced during pipeline processing and saved in the FITS headers and, afterwards, ingested into a relational database that serves a number of report-generating tools. QC measures includes: sky brightness and noise, average stellar ellipticity and seeing, astrometric calibration errors, per-image and nightly-averaged photometric zero points and errors and the number of detected sources per chip. The QC system has been used also to investigate the near-infrared sky brightness at Mauna Kea Observatory over a period of 3 semesters.

Riello, M.; Irwin, M.

152

Service quality control mechanisms in franchise networks  

Microsoft Academic Search

This paper reports the study of some factors that influence the control intensity exerted by franchisors on the service quality provided by the franchised units of their networks and what interdependencies exist between the different mechanisms that can be used to monitor service quality. On the one hand, three control mechanisms of conformance quality are considered, namely audits, mystery shoppers,

Roberto Sánchez Gómez; Isabel Suárez González; Luis Vazquez Suárez

2011-01-01

153

Statistical quality control through overall vibration analysis  

Microsoft Academic Search

The present study introduces the concept of statistical quality control in automotive wheel bearings manufacturing processes. Defects on products under analysis can have a direct influence on passengers’ safety and comfort. At present, the use of vibration analysis on machine tools for quality control purposes is not very extensive in manufacturing facilities.Noise and vibration are common quality problems in bearings.

Ma Carmen Carnero; Rafael González-Palma; David Almorza; Pedro Mayorga; Carlos López-Escobar

2010-01-01

154

[Implementation of the technical requirements of the UNE-EN-ISO 15189 quality standard in a mycobacterial laboratory].  

PubMed

The UNE-EN-ISO 15189:2007 standard defines the requirements for quality and competence that must be met by medical laboratories. These laboratories should use this international standard to develop their own quality management systems and to evaluate their own competencies; in turn, this standard will be used by accreditation bodies to confirm or recognize the laboratories' competence. In clinical microbiology laboratories, application of the standard implies the implementation of the technical and specific management requirements that must be met to achieve optimal quality when carrying out microbiological tests. In Spain, accreditation is granted by the Spanish Accreditation Body (Entidad Nacional de Acreditación). This review aims to discuss the practical application of the standard's technical requirements in mycobacterial laboratory. Firstly, we define the scope of accreditation. Secondly, we specify how the items of the standard on personnel management, control of equipment, environmental facilities, method validation, internal controls and customer satisfaction surveys were developed and implemented in our laboratory. PMID:23453231

Guna Serrano, M del Remedio; Ocete Mochón, M Dolores; Lahiguera, M José; Bresó, M Carmen; Gimeno Cardona, Concepción

2013-02-01

155

Quality control of moxalactam susceptibility disks.  

PubMed Central

In vitro evaluation of two types of moxalactam disks revealed significant performance differences when Staphylococcus aureus was being tested. The differences were traced to the amount of decarboxylated moxalactam present in the disks. The decarboxylated analog was much more active than the parent compound against S. aureus, not active against Pseudomonas aeruginosa, and approximately as active as the parent compound against Escherichia coli. A nine-laboratory coordinated study was performed to establish quality control parameters for 30-micrograms moxalactam disks. Problems with the establishment of interpretive standards for moxalactam disk tests were evaluated in the light of differences between disks utilized in earlier studies and those that are now commercially available. The type of disk greatly influences standards for tests with S. aureus but has insignificant influence on testing gram-negative bacilli.

Barry, A L; Preston, D A; Jones, R N; Gavan, T L; Thornsberry, C

1983-01-01

156

23 CFR 1340.8 - Quality control.  

Code of Federal Regulations, 2013 CFR

... UNIFORM CRITERIA FOR STATE OBSERVATIONAL SURVEYS OF SEAT BELT USE Survey Design Requirements § 1340.8 Quality... Observers and quality control monitors involved in seat belt use surveys shall have received training in data...

2013-04-01

157

QUALITY CONTROL - VARIABILITY IN PROTOCOLS  

EPA Science Inventory

The EPA Risk Reduction Engineering Laboratoryâ??s Quality Assurance Office, which published the popular pocket guide Preparing Perfect Project Plans, is now introducing another quality assurance reference aid. The document Variability in Protocols (VIP) was initially designed as a ...

158

Quality Indicators to Detect Pre-Analytical Errors in Laboratory Testing  

PubMed Central

Pre-analytical steps, the major source of mistakes in laboratory diagnostics, arise during patient preparation, sample collection, sample transportation, sample preparation, and sample storage. However, while it has been reported that the pre-analytical phase is error-prone, only recently has it been demonstrated that most errors occur in the ‘pre-pre-analytical phase’. This comprises the initial procedures of the testing process performed by healthcare personnel outside the laboratory walls and outside the direct control of the clinical laboratory. Quality indicators (QIs) should therefore cover all steps in the pre-analytical phase, from test requesting to sample storage. In the present paper, the state-of-the-art of QIs in laboratory testing is described. The focus is on the experience of a working group of the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) in developing a model of QIs, 16 of which concern the pre-analytical phase.

Plebani, Mario

2012-01-01

159

DEVELOPMENT OF SUSPENDED SOLIDS QUALITY CONTROL AND PERFORMANCE EVALUATION SAMPLES  

EPA Science Inventory

A two phase study was conducted to develop a synthetic suspended solids sample for use as quality control check and performance evaluation within environmental monitoring laboratories. The first phase consisted of a feasibility study to determine compounds that exhibited the opti...

160

Quality assurance and quality control for the Confinement Physics Research Facility (CPRF) and ZTH experiment  

Microsoft Academic Search

In compliance with DOE (US Department of Energy) order 5700.6B, which establishes policies to assure quality achievement in DOE programs, Los Alamos National Laboratory instituted a quality assurance and control (QA) program whose primary goal is to assure that reliable components are available with which to assemble the Confinement Physics Research Facility (CPRF)\\/ZTH experiment. The Code of Federal Regulations 10

R. W. Jr

1989-01-01

161

Dietary Supplement Laboratory Quality Assurance Program: The First Five Exercises  

PubMed Central

The National Institute of Standards and Technology (NIST) has established a Dietary Supplement Laboratory Quality Assurance Program (DSQAP) in collaboration with the National Institutes of Health Office of Dietary Supplements. Program participants measure concentrations of active and/or marker compounds as well as nutritional and toxic elements in food and dietary supplements distributed by NIST. Data are compiled at NIST, where they are analyzed for accuracy relative to reference values and concordance among the participants. Performance reports and certificates of completion are provided to participants, which can be used to demonstrate compliance with current Good Manufacturing Practices as promulgated by the U.S. Food and Drug Administration. The DSQAP has conducted five exercises to date, with total participation including more than 75 different laboratories and many more individual analysts.

Phillips, Melissa M.; Rimmer, Catherine A.; Wood, Laura J.; Lippa, Katrice A.; Sharpless, Katherine E.; Duewer, David L.; Sander, Lane C.; Betz, Joseph M.

2011-01-01

162

Association between product quality control and process quality control of bulk milk  

Microsoft Academic Search

Assessment of dairy-milk quality is based on product quality control (testing bulk-milk samples) and process quality control (auditing dairy farms). It is unknown whether process control improves product quality. To quantify possible association between product control and process control a statistical analysis was conducted. The analysis comprised 64.373 audit results on 26,953 dairy farms and all conducted lab tests of

A. Velthuis; Asseldonk van M. A. P. M

2010-01-01

163

Organization of the doping control laboratory in the Athens 2004 Olympic Games: A case study  

Microsoft Academic Search

The organization with special attention to the Quality Assurance system of the Doping Control Laboratory of Athens (DCLA) implemented during the Athens 2004 Olympic Games is presented in this study. The DCLA has been accredited by the International Olympic Committee (IOC)\\/World Anti-Doping Agency (WADA) following the requirements of the WADA International Standard for Laboratories (ISL) and by ESYD, the greek

A. G. Fragkaki; I.-P. Leontiou; N. Kioukia-Fougia; M. Tsivou; M.-?. ?. Spyridaki; C. G. Georgakopoulos

2006-01-01

164

Quality Control in Small Groups  

NASA Astrophysics Data System (ADS)

The smallness of some groups in a set up to control the quality of a service using questionnaires limits the size of the samples, this limitation has several consequences. Indeed the common approach used for relatively large groups, based on the central limit theorem and the law of large numbers, cannot be used anymore to construct estimators for the parameters of the model. Using an inverse probability will lift these restrictions. A questionnaire is a collection of items. In an item the respondent indicates on a Likert scale his or her agreement with a statement. Dimensions are a set of items dealing with one aspect of the service. In a questionnaire several dimensions are addressed but usually the items are presented in a random sequence. The model for an item is hierarchical with following components: a multivariate hypergeometric model takes the sampling in a finite population into account, the multinomial serves as a prior for the sampling and the Dirichlet-distribution serves as a prior for the multinomials. The composition of dimensions allows to use the posterior for one of the items as a prior for another item of that dimension and so on. After analysis of several questionnaires using this model, the reliability of the responses from some respondents turned out to be a key-problem, in the sense the responses can be classified into at least two classes and a decision rule had to be developed to neglect some of them. The influence of rejecting some answers, on the confidence for the most plausible statement can be estimated. This leads often to the result that there is only minimal evidence for the most probable statement.

Lemmens, L. F.

2008-11-01

165

DEVELOPMENT OF AN ENVIRONMENTAL QUALITY TEACHING LABORATORY AND SUPPLEMENTARY EXPERIENTIAL LEARNING ACTIVITIES  

Technology Transfer Automated Retrieval System (TEKTRAN)

In an effort to improve the ability of agriculturally and environmentally oriented graduates to work in interdisciplinary teams to solve problems, an environmental quality teaching laboratory was developed. In this laboratory, virtual, field, and laboratory experiences provide the experiential and ...

166

40 CFR 51.359 - Quality control.  

Code of Federal Regulations, 2010 CFR

...steady-state test equipment. States may adjust calibration schedules and other quality control frequencies by using statistical process control to monitor equipment performance on an ongoing basis. (2) For analyzers that use ambient air as...

2010-07-01

167

40 CFR 51.359 - Quality control.  

Code of Federal Regulations, 2010 CFR

...steady-state test equipment. States may adjust calibration schedules and other quality control frequencies by using statistical process control to monitor equipment performance on an ongoing basis. (2) For analyzers that use ambient air as...

2009-07-01

168

Quality Control Technician Curriculum. An Elusive Butterfly.  

ERIC Educational Resources Information Center

Defining and developing a quality control technician curriculum for an associate degree program is a difficult and puzzling job. There are as many definitions of quality control and curriculum ideas as there are educators asked. However, one could start by dividing the field into its major areas--heavy manufacturing, maintenance, research, and…

Holler, Michael

169

Control of Microbiological Hazards in the Laboratory.  

National Technical Information Service (NTIS)

Occupational disease occurs at a significant frequency among laboratory workers handling infectious cultures and infected animals. The severity of laboratory infections, in terms of case fatality rate, is higher than the fatality rates for motor vehicle a...

G. B. Phillips

1964-01-01

170

Establishing a Molecular Diagnostic Testing Quality Assurance Program for Detection of Infectious Diseases Validation of Molecular Tests at the North Carolina State Laboratory of Public Health  

Microsoft Academic Search

High-quality clinical laboratory services are critical for public health. Accurate and timely laboratory results are important in identifying, tracking, controlling, and preventing public health threats. For the past 20 years, molecular diagnostic assays have been available for infectious disease detection. These technologies have played and continue to play a critical role in clinical laboratories. Molecular diagnostic testing offers laboratories the

Shermalyn R. Greene

171

A proficiency test scheme for the quality control of black tea and development of quality control material for internal quality control  

Microsoft Academic Search

A proficiency test (PT) was organized for quality control analysis of black tea. Test materials for the analyses of total\\u000a content of powder tea, moisture, total ash, acid-insoluble ash, water-soluble ash, alkalinity of water-soluble ash, water\\u000a extract, crude fiber and caffeine were sent to the participant laboratories (n:43) in 2009. The assigned value, standard deviation of the parameters and z-scores

Cemalettin Baltac?; Huri ?lyaso?lu; Sevim Beyza Öztürk Sar?kaya; Sevda Cavrar; Nurettin Yayl?

172

Maintaining data quality in an environmental testing laboratory  

SciTech Connect

In today's competitive and highly litigious world, it is critical that any laboratory generating data for the environmental and allied industries have a world-class Quality Assurance Program. This Plan must conform to the requirements of every agency and client with whom the lab does business. The goal of such a program is data defensibility; i.e., data validity. Data (usually qualitative analyte [compound or element] identifications and quantitative numerical results) are the end results of nearly all analytical laboratory processes, and the source of revenue. Clients pay for results. The clients expect the results to be accurate, precise, and repeatable. If their data has to go to court, the laboratory will be called upon to defend the accuracy and precision of their work. Without a strong QA program, this will be impossible. The potential implications and repercussions of non-defensible lab data are far-reaching and very costly in terms of loss of future revenues and in legal judgments.

Cohen, Roy J.

2001-03-05

173

Broth Microdilution Susceptibility Testing of Brucella Species: Quality Control Limits for Ten Antimicrobial Agents against Three Standard Quality Control Strains  

Microsoft Academic Search

Brucella broth without supplementation is the recommended medium for broth microdilution susceptibility tests of Brucella abortus, B. melitensis, and B. suis. Based on an eight-laboratory collaborative study using a pH-adjusted modification of this medium, we propose MIC quality control ranges for three control strains against 10 antimicrobials that are potentially efficacious for treating infections caused by these agents of bioterrorism.

Steven D. Brown; Maria M. Traczewski

2005-01-01

174

Automated quality control in Computed Radiography  

Microsoft Academic Search

Purpose.  The purpose of this paper is to describe the automation of quality control procedures on photostimulable imaging plates by\\u000a means of an image-processing tool providing automatic reading of the images and automatic calculation of the quality parameters\\u000a monitored.\\u000a \\u000a \\u000a \\u000a Materials and methods.  Quality-control procedures were performed according to the main available guidelines. The quality assurance programme was\\u000a applied to several Kodak and

R. Ropolo; O. Rampado; P. Isoardi; A. Izzo; L. Savio; T. Cammarota; O. Davini; R. De Lucchi; G. Gandini

2006-01-01

175

Water Quality Control, Curriculum Guide.  

ERIC Educational Resources Information Center

Activities which study how water is used, contaminated, and treated or purified are presented in this curriculum guide, culminating in the investigation of a local water quality problem. Designed as a 12 week mini-course for students in grades eight and nine, the guide first presents a review of the content, objectives, major concepts, and sources…

Washington City Board of Education, NC.

176

Water Quality Control, Curriculum Guide.  

ERIC Educational Resources Information Center

|Activities which study how water is used, contaminated, and treated or purified are presented in this curriculum guide, culminating in the investigation of a local water quality problem. Designed as a 12 week mini-course for students in grades eight and nine, the guide first presents a review of the content, objectives, major concepts, and…

Washington City Board of Education, NC.

177

Control by quality: proposition of a typology.  

PubMed

The application of Quality tools and methods in industrial management has always had a fundamental impact on the control of production. It influences the behavior of the actors concerned, while introducing the necessary notions and formalizations, especially for production systems with little or no automation, which constitute a large part of the industrial activity. Several quality approaches are applied in the workshop and are implemented at the level of the control. In this paper, the authors present a typology of the various approaches that have successively influenced control, such as statistical process control, quality assurance, and continuous improvement. First the authors present a parallel between production control and quality organizational structure. They note the duality between control, which is aimed at increasing productivity, and quality, which aims to satisfy the needs of the customer. They also note the hierarchical organizational structure of these two systems of management with, at each level, the notion of a feedback loop. This notion is fundamental to any kind of decision making. The paper is organized around the operational, tactical, and strategic levels, by describing for each level the main methods and tools for control by quality. The overview of these tools and methods starts at the operational level, with the Statistical Process Control, the Taguchi technique, and the "six sigma" approach. On the tactical level, we find a quality system approach, with a documented description of the procedures introduced in the firm. The management system can refer here to Quality Assurance, Total Productive Maintenance, or Management by Total Quality. The formalization through procedures of the rules of decision governing the process control enhances the validity of these rules. This leads to the enhancement of their reliability and to their consolidation. All this counterbalances the human, intrinsically fluctuating, behavior of the control operators. Strategic control by quality is then detailed, and the two main approaches, the continuous improvement approach and the proactive improvement approach, are introduced. Finally, the authors observe that at each of the three levels, the continuous process improvement, which is a component of Total Quality, becomes an essential preoccupation for the control. Ultimately, the recursive utilization of the Deming cycle remains the best practice for the control by quality. PMID:12512551

Pujo, P; Pillet, M

178

[Comparing quality measurements Part 2: control charts].  

PubMed

Comparative quality measurements and evaluations in nursing play significant roles. Quality measures are affected by systematic and random error. Statistical Process Control (SPC) offers a method to take random variation adequately into account. In this article, control charts are introduced. Those are graphical displays to show quality measures over time. Attribute variables can be displayed by p-, u- and c-control charts. Special cause variations within the processes can be detected by rules. If signs for special cause variations are absent, the process in considered being in statistical control showing common cause variation. A deviation of one data point greater than three standard deviations from the arithmetic mean is considered the strongest signal for non random variation within the process. Within quality improvement contexts control charts outperform traditional comparisons of means and spreads. PMID:23535476

Kottner, Jan; Hauss, Armin

2013-04-01

179

Does laboratory automation for the preanalytical phase improve data quality?  

PubMed

Our aim was to evaluate whether automation for the preanalytical phase improves data quality. Blood from 100 volunteers was collected into two vacuum tubes. One sample from each volunteer was respectively assigned to (G1) traditional processing, starting with centrifugation at 1200g for 10 min, and (G2) the MODULAR PRE-ANALYTICALS EVO-MPA system. The routine clinical chemistry tests were performed in duplicate on the same instrument Cobas 6000 module. G1 samples were uncapped manually and immediately placed into the instrument. G2 samples were directly fed from the MPA system to the instrument without further staff intervention. At the end, (1) the G1 samples were stored for 6 h at 4 °C as prescribed in our accredited laboratory and (2) the G2 samples were stored for 6 h in the MPA output buffer. Results from G1 and G2, before and after storage, were compared. Significant increases were observed in G1 compared with G2 samples as follows: (1) before storage for alkaline phosphatase (ALP), lactate dehydrogenase (LDH), phosphate (P), magnesium (MG), iron (FE), and hemolysis index and (2) after storage for total cholesterol (COL), triglycerides (TG), total protein (TP), albumin (ALB), blood urea nitrogen (BUN), creatinine (CRE), uric acid (UA), ALP, pancreatic amylase, aspartate aminotransferase (AST), alanine aminotransferase (ALT), g-glutamyltransferase (GGT), LDH, creatine kinase (CK), calcium (CA), FE, sodium (NA), potassium (K), and hemolysis index. Moreover, significant increases were observed in (3) G1-after versus G1-before storage samples for COL, high-density lipoprotein cholesterol, TG, TP, ALB, BUN, CRE, UA, AST, ALT, GGT, LDH, P, CA, MG, FE, NA, K, and hemolysis index and (4) G2-after versus G2-before storage only for BUN, AST, LDH, P, and CA. In conclusion, our results show that the MPA system improves the quality of laboratory testing. PMID:23686657

Lima-Oliveira, Gabriel; Lippi, Giuseppe; Salvagno, Gian Luca; Danese, Elisa; Montagnana, Martina; Brocco, Giorgio; Voi, Monica; Picheth, Geraldo; Guidi, Gian Cesare

2013-05-17

180

[Quality control of printed patient information].  

PubMed

Printed material is an important part in patient information and is called bibliotherapy. It is subject to quality control similar to any other types of treatment. This paper presents an outline of important quality criteria and methods of quality control. Important quality criteria are: (a) Correctness and validity of content evaluated by mentioning the expertise of the authors, appraisal through external experts, reference to scientific literature, and empirical tests of the content, (b) Readability in respect to text structure measured by the "Flesch-Reading-Ease-Formula" supported by fair graphical design including fond and structure of text, (c) Comprehensibility tested by feedback of patients or standardized by the Hamburg comprehensibility rating, (d) Utility including securing availability, acceptance, differential indication and use. Writing and publication of patient leaflets must be accompanied by quality control measures. PMID:23446824

Herm, Kerstin; Linden, Michael

2013-02-27

181

Quality of Nosocomial Infection Control in Thailand  

Microsoft Academic Search

Objective : To study the quality of nosocomial infection control with respect to structure and process. Material and Method : Data collection by questionnaire and interview administrators and medical personnel in 57 hospitals in Thailand in 2002. Results : Nosocomial infection control was implemented in all 57 hospitals. In every hospital, there was an infection control committee (ICC) and at

Somwang Danchaivijitr; Anuwat Supchutikul; Sribenja Watayapiches RN; Kanchana Kachintorn RN

182

Quality or Control? Management in Higher Education  

ERIC Educational Resources Information Center

Over the past fifteen years the rationale, organisational infrastructure and delivery of social policy in Britain have undergone radical transformation. Whereas efficiency was the key word of the 1980s, quality was the touchstone of the 1990s and quality control with accountability has become the management philosophy of the new millennium.…

Milliken, John; Colohan, Gerry

2004-01-01

183

Drinking water quality standards and controls  

Microsoft Academic Search

Intended as a handy reference guides for sanitary engineers, public health administrators, or water treatment professionals, Drinking Water Quality Standards is designed as a one-stop' evaluation of water quality controls issues - both from the source to the treatment plant and from the distribution system to the consumer. Because of the concern generated by recent discoveries of contaminants in potable

Zuane; J. De

1990-01-01

184

Striving for Quality Control in Distance Education.  

ERIC Educational Resources Information Center

Discussion of the benefits and drawbacks of distance education and online instruction in higher education focuses on quality control. Topics include quality of product, of learning, and of technology; student prerequisites; instructional design; faculty support systems; and program design, including professional development versus academic degree…

Leh, Amy S. C.; Jobin, Andrianna

2002-01-01

185

Network-based production quality control  

Microsoft Academic Search

This study investigates the feasibility of remote quality control using a host of advanced automation equipment with Internet accessibility. Recent emphasis on product quality and reduction of waste stems from the dynamic, globalized and customer-driven market, which brings opportunities and threats to companies, depending on the response speed and production strategies. The current trends in industry also include a wide

Yongjin Kwon; Bill Tseng; Richard Chiou

2007-01-01

186

CLAY LINER CONSTRUCTION AND QUALITY CONTROL  

EPA Science Inventory

Soil handling and liner construction practices at hazardous waste management facilities are documented. Soil characterizations, processing techniques, construction methods, and quality control of constructed liners are reviewed and compared. Results indicate widely different test...

187

The Quality Control of Search Analysts.  

ERIC Educational Resources Information Center

|Proposes that a search service concentrate on a quality control program for online database search analysts which consists of selection, monitoring during the training process, and certification that will begin prior to training with the preselection of search analysis. (CWM)|

Dolan, Donna R.; Kremin, Michael C.

1979-01-01

188

Los Alamos National Laboratory Associate Directorate for Physics and Life Sciences Quality Program  

SciTech Connect

This report discusses the following on Los Alamos National Laboratory: laboratory mission with physics and life sciences goals; physics and life sciences quality requirements and guidance documents basis; process flow-down of documentation; line-organization internal and external assessments; laboratory management issues under development; and the quality assurance management plan.

Mignardot, H.

1993-03-01

189

Los Alamos National Laboratory Associate Directorate for Physics and Life Sciences Quality Program  

SciTech Connect

This report discusses the following on Los Alamos National Laboratory: laboratory mission with physics and life sciences goals; physics and life sciences quality requirements and guidance documents basis; process flow-down of documentation; line-organization internal and external assessments; laboratory management issues under development; and the quality assurance management plan.

Mignardot, H.

1993-01-01

190

Product liability, quality control and insurance  

Microsoft Academic Search

In order to protect consumers many governments have introduced strict legislation on product liability. Manufacturers can\\u000a then either establish a strict system of quality control, or try to have their liability covered by insurance. Statistical\\u000a quality control will give information about the probability that a consumer shall buy a defective product, and be entitled\\u000a to claim compensation. This probability is

Karl Borch

1978-01-01

191

Aerospace Materials Quality Control: Instructor Notes  

NSDL National Science Digital Library

This document from the Aerospace Manufacturing Education Project is intended to accompany a PowerPoint presentation on the topic of quality control of materials used in the aerospace industry. That presentation is available for download here. The presentation and notes will help students understand why quality control is important in this field. They also include details about aerospace QC teams and techniques, including non-destructive testing. These instructor notes also include links to a number of useful online references.

2012-11-14

192

QUALITY CONTROL FOR RESEARCH STUDIES: A CRITICAL PART OF THE QUALITY SYSTEM AT THE U. S. EPA  

EPA Science Inventory

QUALITY CONTROL FOR RESEARCH STUDIES: A CRITICAL PART OF THE QUALITY SYSTEM AT THE U.S. EPA Mette C.J. Schladweiler, Scientist, and Thomas J. Hughes, QA and Records Manager, Experimental Toxicology Division (ETD), National Health and Environmental Effects Research Laboratory (NHE...

193

National Research Laboratory Generic Project Quality Assurance Plan for research and development  

Microsoft Academic Search

This Project Quality Assurance Plan (PQAP) sets forth the requirements for the National Research Laboratory's research Divisions' quality assurance programs to comply with the applicable criteria of 10CFR Part 50, Appendix B, ANSI\\/ASME NQA-1 and to meet the requirements of the Funding Agency's Quality Assurance Specification and the National Research Laboratory's QA Program for the projects that require a formal

E. E. Bain; R. L. Hinckley

1986-01-01

194

Intraoperative quality control in vascular surgery.  

PubMed

Since graft patency is the predominant predictor of long-term survival after vascular surgery, intraoperative graft patency control is of major importance for improving quality assurance. Intraoperative quality control is of major importance to obtain good short- and longterm results and to eliminate the need for reoperation. Currently there is no standardized approach and intraoperative quality control is not performed routinely by most surgeons. The most commonly used intraoperative assessment techniques include arteriography, duplex ultrasonography, angioscopy and transit-time flow measurement (TTFM). Fluorescent angiography (FA) using the dye indocyanine green (ICG) is a novel noninvasive technology for intraoperative visualization and documentation of vessels, bypass grafts, and perfusion with an infrared sensitive imaging device, so far validated for quality control in coronary bypass surgery. FA and TTFM are methods for quantitative assessment of blood flow measurement, which are currently exclusively used as intraoperative quality control in cardiac bypass surgery. Up to now, there are no experiences published for peripheral vascular reconstructions. However, transposition and implementation of these techniques seem to be valuable and useful. Therefore further studies for intraoperative quality control in vascular surgery are necessary. PMID:22433733

Wipper, S; Detter, C; Lohrenz, C; Debus, E S

2012-02-01

195

QUALITY ASSURANCE AND QUALITY CONTROL FOR RADIOCHEMICAL ANALYSES AND MEASUREMENTS  

EPA Science Inventory

Require that each batch of samples analyzed be accompanied by appropriate quality control samples to evaluate accuracy and precision of the results. Require a documented data review and validation process by a minimum of three people before data is released to the client. Requi...

196

Real-time quality control: the French Minitel system.  

PubMed

A prototype system designed to provide real-time response to inter-laboratory proficiency testing results has been developed using the French Minitel telecommunication system. This nationwide computer networking system allows for instantaneous reporting and evaluation of results obtained on external quality assessment (EQA) samples. If a certain test is in error and presumably out of control the problem can be remedied immediately with obvious advantages to patient care. PMID:2282753

Goguel, A; LeBlanc, A

1990-01-01

197

Capillary electrophoresis of proteins in a quality control environment.  

PubMed

A method for determining the purity of recombinant carboxypeptidase B utilizing CE-SDS has been developed and validated for use in a manufacturing quality control laboratory. The method was optimized, prior to validation, to allow for the lowest limit of quantitation. The method was validated with the typical ICHQ2A parameters, including accuracy, linearity, LOQ, precision, robustness/ruggedness, and specificity. All validation parameters met the acceptance criteria defined in the validation protocol. PMID:15163855

Good, David L; Cummins-Bitz, Stacey; Fields, Raeann M; Nunnally, Brian K

2004-01-01

198

Total Quality Management: An Application in a Research and Development Laboratory.  

National Technical Information Service (NTIS)

In September 1988, the Air Force Human Resources Laboratory (AFHRL) took initial steps to set up a Total Quality Management (TQM) program in the Laboratory. The implementation procedure used was the Method for Generating Efficiency and Effectiveness Measu...

H. J. Clark

1989-01-01

199

Slew Maneuvers of Spacecraft Control Laboratory Experiment (SCOLE).  

National Technical Information Service (NTIS)

This is the final report on the dynamics and control of slew maneuvers of the Spacecraft Control Laboratory Experiment (SCOLE) test facility. The report documents the basic dynamical equation derivations for an arbitrary large angle slew maneuver as well ...

Y. P. Kakad

1992-01-01

200

On Product Liability and Quality Control  

Microsoft Academic Search

Product liability is one of the most costly and confusing problems facing manufacturing today. In this paper, models of the economic impact of both final acceptance sampling and process control on liability risk due to a manufacturing defect are presented. A numerical example reveals that selection of cost-effective quality control methods depends on assumed disposition of rejected lots.

Ann S. Marucheck

1987-01-01

201

42 CFR 84.40 - Quality control plans; filing requirements.  

Code of Federal Regulations, 2011 CFR

...2011-10-01 2011-10-01 false Quality control plans; filing requirements. 84.40 Section...APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Quality Control § 84.40 Quality control plans; filing requirements. As a...

2011-10-01

202

18 CFR 12.40 - Quality control programs.  

Code of Federal Regulations, 2011 CFR

...Engineer. If a quality control program is required, the construction, repair, or...performed by a construction contractor, quality control inspection...prohibit additional quality control inspections by the construction contractor,...

2013-04-01

203

30 CFR 28.30 - Quality control plans; filing requirements.  

Code of Federal Regulations, 2013 CFR

... 1 2013-07-01 2013-07-01 false Quality control plans; filing requirements. 28.30...PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.30 Quality control plans; filing requirements....

2013-07-01

204

42 CFR 84.40 - Quality control plans; filing requirements.  

Code of Federal Regulations, 2012 CFR

... 1 2012-10-01 2012-10-01 false Quality control plans; filing requirements. 84.40... APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Quality Control § 84.40 Quality control plans; filing requirements....

2012-10-01

205

46 CFR 164.120-11 - Production quality control requirements.  

Code of Federal Regulations, 2012 CFR

... 2012-10-01 false Production quality control requirements. 164.120-11...Boats § 164.120-11 Production quality control requirements. The resin manufacturer must institute a quality control procedure to ensure...

2012-10-01

206

21 CFR 640.56 - Quality control test for potency.  

Code of Federal Regulations, 2013 CFR

...2013-04-01 false Quality control test for potency...SERVICES (CONTINUED) BIOLOGICS ADDITIONAL STANDARDS...640.56 Quality control test for potency... (c) The quality control test for potency...Director, Center for Biologics Evaluation and...

2013-04-01

207

CONTROL ASSAY DEVELOPMENT: METHODOLOGY AND LABORATORY VERIFICATION  

EPA Science Inventory

The report describes Control Assay Development (CAD), a data acquisition program designed to evaluate the potential applicability of various treatment processes for the control of solid, liquid, and gaseous emissions from coal conversion plants. The CAD program described could be...

208

Quality control by a mobile molecular workshop: Quality versus quantity  

NASA Astrophysics Data System (ADS)

Ribosome is a molecular machine that moves on a messenger RNA (mRNA) track while, simultaneously, polymerizing a protein using the mRNA also as the corresponding template. We define, and analytically calculate, two different measures of the efficiency of this machine. However, we argue that its performance is evaluated better in terms of the translational fidelity and the speed with which it polymerizes a protein. We define both these quantities and calculate these analytically. Fidelity is a measure of the quality of the products, while the total quantity of products synthesized in a given interval depends on the speed of polymerization. We show that for synthesizing a large quantity of proteins, it is not necessary to sacrifice the quality. We also explore the effects of the quality control mechanism on the strength of mechanochemical coupling. We suggest experiments for testing some of the ideas presented here.

Sharma, Ajeet K.; Chowdhury, Debashish

2010-09-01

209

Quality control in immunocytochemistry: experiences with the oestrogen receptor assay.  

PubMed Central

AIMS: To evaluate the feasibility of an interlaboratory quality control programme in immunohistochemistry. METHODS: Several pathology laboratories were asked to carry out immunohistochemical oestrogen receptor staining on a set of freeze dried cryostat sections of breast cancer tissue. The sections and protocols for staining and semi-quantitative scoring were mailed to the participating laboratories in two trials. The oestrogen receptor content of the breast cancer samples was determined by radioligand binding assay on the tumour cytosol. RESULTS: In the first trial 11 laboratories (response rate 60%) participated. Eight (73%) of the participants scored within a 95% confidence interval and all but one correctly classified the tumour as receptor positive. In the second trial all 20 participating laboratories (response rate 55%) correctly scored one tumour sample as negative and 18 of them (90% of respondents) correctly classified the two other tumour samples as receptor positive. In a quantitative evaluation a histochemical score within 95% confidence interval limits was provided by eight (40%) and 12 (60%) of the participants. CONCLUSIONS: Semiquantitative scoring of immunocytochemical staining is valuable for performing correlative inter-laboratory studies, although this scoring protocol may not be required for diagnosis or prognosis. Significant inter-laboratory variability exists, leading to qualitatively correct receptor classification in 100% of receptor negative and 80% of receptor positive cases, and quantitative agreement in only about half of the cases. The perceived variability is not caused by systematic differences in the choice of the immunocytochemical technique, or the mailing of freeze dried sections. Quality control programmes should be included in the standard procedures of each diagnostic immunohistochemistry laboratory. Images

Bosman, F. T.; de Goeij, A. F.; Rousch, M.

1992-01-01

210

Cellular Strategies of Protein Quality Control  

PubMed Central

Eukaryotic cells must contend with a continuous stream of misfolded proteins that compromise the cellular protein homeostasis balance and jeopardize cell viability. An elaborate network of molecular chaperones and protein degradation factors continually monitor and maintain the integrity of the proteome. Cellular protein quality control relies on three distinct yet interconnected strategies whereby misfolded proteins can either be refolded, degraded, or delivered to distinct quality control compartments that sequester potentially harmful misfolded species. Molecular chaperones play a critical role in determining the fate of misfolded proteins in the cell. Here, we discuss the spatial and temporal organization of cellular quality control strategies and their implications for human diseases linked to protein misfolding and aggregation.

Chen, Bryan; Retzlaff, Marco; Roos, Thomas; Frydman, Judith

2011-01-01

211

Laboratory observation of quantum control level sets  

SciTech Connect

In controlled quantum dynamics, a level set is defined as the collection of control fields that produce a specific value for a particular observable. This paper explores the relationship between individual solutions to a control problem, and presents the first experimentally observed quantum control level sets, which are found to be continuous submanifolds. Level sets are observed for two photon transitions where the control is the spectral phase function, which is expressed as a fourth-order polynomial. For the systems studied here, the level sets are shown to be closed surfaces in the spectral phase control space. A perturbation analysis provides insight into the observed topology of the level set, which is shown to be preserved by the low-order polynomial phase representation. Each of the multiple control fields forming a level set preserves the observable value by its own distinct manipulation of constructive and destructive quantum interferences. Thus, the richness of quantum control fields meeting a particular observable value is accompanied by an equally diverse family of control mechanisms.

Roslund, Jonathan; Roth, Matthias; Rabitz, Herschel [Department of Chemistry, Princeton University, Princeton, New Jersey 08544 (United States)

2006-10-15

212

Quality assurance programs at the PNL calibrations laboratory  

Microsoft Academic Search

The calibrations laboratory at Pacific Northwest Laboratory (PNL) serves as a radiological standardization facility for personnel and environmental dosimetry and radiological survey instruments. As part of this function, the calibrations laboratory must maintain radiological reference fields with calibrations traceable to the National Institute of Standards and Technology (NIST). This task is accomplished by a combination of (1) sources or reference

R. K. Piper; J. C. McDonald; R. A. Fox; F. N. Eichner

1993-01-01

213

[Quality control of surgical care (author's transl)].  

PubMed

Based on studies carried on for more than ten years, various methods for voluntary quality control of surgical care are proposed. Besides short-term measures (e.g., "strategy of therapy"), a long-term pilot study would permit detection of defects and errors in surgical care through the recording of comparable data. An organization (similar to the Dutch "Concilium chirurgicum") should sponser visitations to various surgical centers. These two, strictly voluntary measures should form the basis for quality control that boots self-esteem of surgeons and does away with the need for state-sponsored measures. PMID:593000

Müller-Osten, W

1977-11-01

214

Quality assurance practices in Europe: a survey of molecular genetic testing laboratories.  

PubMed

In the 2000s, a number of initiatives were taken internationally to improve quality in genetic testing services. To contribute to and update the limited literature available related to this topic, we surveyed 910 human molecular genetic testing laboratories, of which 291 (32%) from 29 European countries responded. The majority of laboratories were in the public sector (81%), affiliated with a university hospital (60%). Only a minority of laboratories was accredited (23%), and 26% was certified. A total of 22% of laboratories did not participate in external quality assessment (EQA) and 28% did not use reference materials (RMs). The main motivations given for accreditation were to improve laboratory profile (85%) and national recognition (84%). Nearly all respondents (95%) would prefer working in an accredited laboratory. In accredited laboratories, participation in EQA (P<0.0001), use of RMs (P=0.0014) and availability of continuous education (CE) on medical/scientific subjects (P=0.023), specific tasks (P=0.0018), and quality assurance (P<0.0001) were significantly higher than in non-accredited laboratories. Non-accredited laboratories expect higher restriction of development of new techniques (P=0.023) and improvement of work satisfaction (P=0.0002) than accredited laboratories. By using a quality implementation score (QIS), we showed that accredited laboratories (average score 92) comply better than certified laboratories (average score 69, P<0.001), and certified laboratories better than other laboratories (average score 44, P<0.001), with regard to the implementation of quality indicators. We conclude that quality practices vary widely in European genetic testing laboratories. This leads to a potentially dangerous situation in which the quality of genetic testing is not consistently assured. PMID:22739339

Berwouts, Sarah; Fanning, Katrina; Morris, Michael A; Barton, David E; Dequeker, Elisabeth

2012-06-27

215

The Good, the Bad, and the Unknown: Quality of Clinical Laboratories in Kampala, Uganda  

PubMed Central

Background Clinical laboratories are crucial in addressing the high rates of communicable and non-communicable diseases seen in sub-Saharan Africa (SSA). However, the most basic information, such as the number and quality of clinical laboratories in SSA, is not available. The objective of this study was to create a practical method for obtaining this information in SSA towns and cities using an initial survey in Kampala, Uganda. Methods Kampala city was divided into 5 partially-overlapping regions. Each region was assigned to 2–3 surveyors who identified and surveyed laboratories in their respective regions; in person and on foot. A modified version of the World Health Organization - African Region (WHO/AFRO) Laboratory Strengthening Checklist was used to obtain baseline measures of quality for all clinical laboratories within Kampala city. The surveyors also measured other attributes of each laboratory, such as their affiliation (government, private etc), designation (national hospital, district hospital, standalone etc), staff numbers, and type of staff. Results The survey team identified and surveyed 954 laboratories in Kampala city. 96% of laboratories were private. Only 45 (5%) of the laboratories met or surpassed the lowest quality standards defined by the WHO/AFRO-derived laboratory strengthening tool (1-star). These 45 higher-quality laboratories were, on average, larger and had a higher number of laboratory-specific staff (technologists, phlebotomists etc) than the other 909 laboratories. 688 (72%) of the 954 laboratories were not registered with the Ministry of Health (MoH). Conclusions This comprehensive evaluation of the number, scope, and quality of clinical laboratories in Kampala is the first published survey of its kind in sub-Saharan Africa. The survey findings demonstrated that laboratories in Kampala that had qualified personnel and those that had higher testing volumes, tended to be of higher-quality.

Elbireer, Ali M.; Jackson, J. Brooks; Sendagire, Hakim; Opio, Alex; Bagenda, Danstan; Amukele, Timothy K.

2013-01-01

216

Hands-On Laboratory Experience via Remote Control: Jet Thrust Laboratory  

Microsoft Academic Search

This paper describes the development of a remote-controlled jet thrust laboratory for illustrating the fundamentals of compressible fluid mechanics as part of an undergraduate mechanical engineering curriculum. The laboratory is the first in a series to be developed jointly by faculty at Rutgers University and the University of Illinois at Urbana-Champagne. The sharing of resources significantly reduces the per institution

Madara Ogot; Gregory Elliott; Nick Glumac

2002-01-01

217

Medicaid Program; Medicaid eligibility quality control, progressive reductions in federal financial participation for FYs 1982-84, payment for physician billing for clinical laboratory services, and utilization control of skilled nursing facility services: removal of obsolete requirements--HCFA. Final rule.  

PubMed

This final rule removes several obsolete sections of the Medicaid regulations that specify rules and procedures for disallowing Federal financial participation for erroneous medical assistance payments due to eligibility and beneficiary liability errors as detected through the Medicaid eligibility quality control program for assessment periods from 1980 through June 1990. The Medicaid regulations that contain the rules and procedures for the progressive reductions in Federal financial participation in medical assistance expenditures made to the States for fiscal years 1982 through 1984 are removed to reflect the repeal of the statutory bases for the reductions. The Medicaid regulations that provide for physician billing for clinical laboratory services that a physician bills or pays for but did not personally perform or supervise are removed to reflect the statutory repeal of this provision. In addition, the rule removes obsolete regulations that prescribe requirements concerning utilization control of Medicaid services furnished in skilled nursing facilities. This rule is part of the Department's initiate to reinvent health care regulations and eliminate obsolete requirements. PMID:10159145

1996-07-24

218

Philip Morris involvement in the development of an air quality laboratory in El Salvador  

PubMed Central

Background: The tobacco industry has organised research institutions to generate misleading data on indoor air quality, including second-hand smoke exposure and health effects. Objectives: To describe tobacco industry involvement in the organisation and financial support of an air quality research laboratory in El Salvador. Methods: Tobacco industry documents on the internet were systematically searched from August 2007 to February 2008 for air quality studies undertaken in El Salvador, and laboratory personnel were interviewed. Results: Philip Morris sought to establish a network of air quality laboratories throughout Latin America. In El Salvador, in 1997, through Tabacalera de El Salvador (a subsidiary of Philip Morris) and the Salvadoran Foundation for Economic Development (FUSADES), the industry organised an air quality research laboratory. FUSADES was part of the industry’s Latin American Scientific Network, which consisted of doctors hired as consultants who would send air samples from their research to FUSADES. Philip Morris Scientific Affairs personnel hired LabStat, a Canadian-based laboratory, to provide technical assistance to FUSADES (train and assist the laboratory in air quality measurements). In addition, the Washington-based HMS Group successfully implemented a plan to upgrade the laboratory and obtain international certifications. HMS Group also assisted in searching for sustainable funding for FUSADES, including seeking funds from international aid for Hurricane Mitch. Conclusion: Air quality studies that have used the FUSADES laboratory should be carefully interpreted, given the support that this laboratory received from Philip Morris.

Kummerfeldt, C E; Barnoya, J; Bero, L

2009-01-01

219

De Ontwikkeling van de Kwaliteitsbeheersing (Developments in Quality Control).  

National Technical Information Service (NTIS)

Developments of quality control and in particular the role of workers and quality managers in it, were surveyed. An increase in demands for quality from the outside (market shift), preventive quality care efficiency, and employee requests for more respons...

M. A. A. Kooter

1983-01-01

220

Practical risk-adjusted quality control charts for infection control  

Microsoft Academic Search

Background:Control chart methodology has been widely touted for monitoring and improving quality in the health care setting. P charts and U charts are frequently recommended for rate and ratio statistics, but their practical value in infection control may be limited because they (1) are not risk-adjusted, and (2) perform poorly with small denominators. The Standardized Infection Ratio is a statistic

Tracy L. Gustafson

2000-01-01

221

Acoustics Laboratories: Active Noise Control Demo  

NSDL National Science Digital Library

The Virginia Polytechnic Institute and State University Department of Mechanical Engineering offers the Active Noise Control Experiment. The page contains an explanation of the experiment and the download file to carry it out. The experiment demonstrates how active noise control cancels a sound wave by sending a single frequency wave to the right computer speaker, which represents the noise to be canceled, and a control wave of equal amplitude and opposite phase to the left speaker to cancel the noise. Although younger kids will most likely need help from teachers or parents to set up or understand the experiment, the very interesting hands-on activity will be enjoyed by nearly every aged student.

1969-12-31

222

7 CFR 58.928 - Quality control tests.  

Code of Federal Regulations, 2011 CFR

...shall be subject to inspection for quality and condition throughout each processing operation. Quality control tests shall be made...composition control. For each batch or production run a keeping quality test shall be made to...

2013-01-01

223

Quality Control in the USIMINAS Coke Plant.  

National Technical Information Service (NTIS)

This paper shows how the philosophy of quality control adopted at USIMINAS is implemented in the Coke Plant. For familiarity with it, the USIMINAS coking operation is briefly described at the outset. Then, because of the functions that the coke will perfo...

M. Fortes D. Machado

1981-01-01

224

Timing control improves seabed survey data quality  

Microsoft Academic Search

Seateam has completed development of and field-proven the Dolphin data acquisition and timing system for high-density surveys offshore. The Dolphin project was initiated to improve quality control of survey sensor data and ensure time synchronization, thus leading to faster turnaround of seabed terrain information. Data received from survey sensors is asynchronous, so the system must provide for data correlation. This

1996-01-01

225

QUALITY CONTROL SYSTEM OF XML BIBLIOGRAPHIC RECORDS  

Microsoft Academic Search

The aim of this paper was not only to define the XML biblio- graphic records format, but also to describe the use of dierent XML stan- dards and o-the-shelf tools in library automation. The quality control system of bibliographic records within the BISIS library software system has been implemented using XML Schema, XSLT and XPath languages, according to UNIMARC bibliographic

Gordana Budimir; Dusan Surla

2004-01-01

226

Supplier-customer interaction in quality control  

Microsoft Academic Search

We develop a game theoretic model of joint quality control in a single sourcing environment which integrates supplier and customer decisions. In this model, both parties behave strategically and take each other's incentives into account when deciding on their respective sampling plans. The specific sampling plans considered are of the “single sample fraction defective with rectifying inspection” type. A method

Diane J. Reyniers

1992-01-01

227

Quality control in bacteriology: preliminary trials  

PubMed Central

Six trials of quality control material sent in the form of artificial specimens are reported. A method of assessment using a computer for complex results, including antibiotic sensitivity tests, was employed. The trials were successful in showing the need for a comprehensive service and in bringing to light by this method a wide variety of errors. Images

Stokes, E. Joan; Whitby, J. L.

1971-01-01

228

Quality Control & Design in Science Learning  

ERIC Educational Resources Information Center

One area of science education that is, at times, neglected involves lessons on technological concepts of these principles--designing, testing, and quality control. Instead, a focus upon science concepts from a pure, and unapplied, perspective is the norm. Thus, while students may learn the equation "mass divided by volume equals density," the…

Sumrall, William J.; Schillinger, Don

2003-01-01

229

Quality Control & Design in Science Learning  

ERIC Educational Resources Information Center

|One area of science education that is, at times, neglected involves lessons on technological concepts of these principles--designing, testing, and quality control. Instead, a focus upon science concepts from a pure, and unapplied, perspective is the norm. Thus, while students may learn the equation "mass divided by volume equals density," the…

Sumrall, William J.; Schillinger, Don

2003-01-01

230

Metropolitan Philadelphia Interstate Air Quality Control Region.  

National Technical Information Service (NTIS)

A listing of the Federal facilities in the metropolitan Philadelphia Interstate Air Quality Control Region (Pennsylvania, Delaware, and New Jersey) is presented. A break-down of type and amount of fuels used by each political division is also tabulated. T...

C. E. Edlund

1970-01-01

231

The “Coupon Collector's Problem” and Quality Control  

Microsoft Academic Search

This article examines the classical “coupon collector's problem” and applies several key results to certain problems in quality control sampling. It is shown how solutions to the coupon sampling problem are readily adaptable to industrial sampling problems where the intent is to sample at least 1 of k specific product unit types in a well mixed stream of product where

Stephen N. Luko

2009-01-01

232

Review of 18F-FDG Synthesis and Quality Control  

PubMed Central

This review article covers a concise account on fludeoxyglucose (18F–FDG) synthesis and quality control procedures with emphasis on practical synthesis Currently, 18F–FDG is the most successful PET radiopharmaceutical so far. The advancement in synthesis and quality control of 18F–FDG, together with its approval by the US FDA and the availability of reimbursement, are probably the main reasons for the flourish of clinical PET over the last 20 years. 18F–FDG can be synthesised by either electrophilic fluorination or nucleophilic fluorination reaction. Nucleophilic fluorination using mannose triflate as precursor and Kryptofix or tetrabutylammonium salts (TBA) is widely used because of higher yield and shorter reaction time. The quality control requirements of 18F–FDG can be found in United States Pharmacopeia (USP), British Pharmacopeia (BP), European Pharmacopeia (EP) and the Chemistry, Manufacturing, and Controls (CMC) section from United States Food and Drug Administration (US FDA) PET draft guidance documents. Basic requirements include radionuclidic identity, radiochemical purity, chemical purity, pH, residual solvent, sterility, and bacterial endotoxin level. Some of these tests (sterility, endotoxins and radionuclidic purity) can be finished after the 18F–FDG has been released. Although USP, BP and EP do not require filter membrane integrity test, many laboratories perform this test as an indirect evident of the product sterility. It is also interesting to note that there are major differences in 18F–FDG quality requirements among USP, BP, and CMC.

Yu, S

2006-01-01

233

Research and Field Laboratories for Water Pollution Control.  

National Technical Information Service (NTIS)

The report describes the location and goals of new research and field laboratories for water pollution control. These laboratories will be in Boston, Mass.; Athens, Ga.; Ann Arbor, Mich.; Ada, Okla.; Covallis, Ore.; College, Alaska; Kingston, R.I.; and Du...

1964-01-01

234

The software laboratory for undergraduate process control education  

Microsoft Academic Search

Simulation exercises are a preferred method for reinforcing process control principles. The Software Laboratory described in this paper enables the student to perform many simulation exercises, some via programming and some via interactive menus. The Software Laboratory facilitates student learning by using technology, terminology, and process examples that are consistent with a course textbook. All programs use the popular MATLAB

Thomas E. Marlin

1996-01-01

235

Experimental control and automation in a laboratory for imprinting research  

Microsoft Academic Search

Offers a prototype for an automated imprinting laboratory. By controlling as many extraneous variables as possible and by eliminating the E from the recording of the dependent variable, it is hoped that variance due to these 2 sources will be reduced, if not eliminated. It is noted that increased variance due to laboratory conditions and E expertise may result in

L. James Shapiro

1970-01-01

236

Laboratory analog for a tropical cyclone: excitation and control  

Microsoft Academic Search

This contribution presents laboratory investigations that are aimed at initiating and controlling a large-scale rotating helical vortex generated in conditions of thermal turbulent convection. The experiments were carried out in a rotating fluid layer with a large aspect ratio of horizontal to vertical dimension and local heating from below in the central zone. Two different laboratory setups were used: with

G. P. Bogatyryov; I. V. Kolesnichenko; G. V. Levina; M. E. Povarnitsyn; A. N. Sukhanovsky

2003-01-01

237

Road profile control methods for laboratory vehicle road simulators  

Microsoft Academic Search

The use of laboratory road simulators has become quite common in the automotive industry. Although laboratory road simulators have reduced testing time, two obstacles to improving process automation remain. First, since traditional simulation control parameters are specimen dependent, new data must be acquired for each specimen to ensure accurate test results, significantly adding to the time and cost of the

Larry Mianzo; David Fricke; Rakan Chabaan

1998-01-01

238

[Quality control in surgery of inguinal hernias].  

PubMed

Quality assurance is a concept intended to ensure the quality of a surgical therapy on a defined level. But what is "quality" in surgical therapy? Quality can be described in a lot of different ways. Quality has something to do with taste, especially with individual preferences. The testing of the quality of wine is a good example. Even though this is quite difficult, it can still be done and has been done for hundreds of years. In surgery we are still at the beginning. Discussions regarding the definition of quality, the best method of quality assurance and, not least, who is responsibility for its measurement are well-known obstacles on the path to improvement. Quality has basically little to do with research. It is not a matter of finding the right technique, but of ensuring that the right technique, when found, is correctly used. Defined quality standards will allow this. Quality standards in inguinal hernia surgery are: outstanding comfort directly before and after the therapy, few or no side effects troubling the patient, most of all no disastrous side effects, disaster, low rate of relapse and, in our times, decent economy. The question: "Is the target to be oriented on the average or must the standard be brought nearer the best performance?" has to be answered. Surgery and average performance do not match; surgical performance cannot be oriented on the average. The next question is: "Which methods are suitable for this?". The "tracer method" is one method, one aspect within quality assurance methods in general. It is designed for obtaining information on the quality of a clinic/department. The obtained data on complication rates, for example (10%), and their striking points should above all give insight into the complete department, i.e., on complication rates of a surgical department in general. The same counts for infection rates or striking points. The essential question remains: "Who should carry it out?" Bureaucrats lacking expertise will buy it. The principle of autonomy, "expertise connected to competence" has to be kept when answering the question of who should do it and how. The tracer method, using hernia surgery as a tracer, is not necessarily suitable as a measure of the quality of inguinal hernia surgery. Even though it supplies--as a side effect--information about inguinal hernia surgery, like complication rates (10%) and relapse operations (10%), as well as the varying anaesthetic procedures, or the use for changes in therapeutic procedures, the tracer method is not suitable to sufficiently inform about the quality of inguinal hernia surgery in particular. A further essential aspect when analysing quality assurance--showing up clearly at the moment--is the fact, that "another" control will develop if this inactivity remains. In this case the "controllers" will certainly not be the surgeons. The nightmare vision of bureaucrats (insurance companies or other parties) as controllers is in sight. This would be the same situation as if Michael Schumacher's Ferrari were checked by clerks and not by engineers. PMID:9483344

Troidl, H

1997-12-01

239

The Quantity and Quality of Biology Laboratory Work in British Columbia High Schools.  

ERIC Educational Resources Information Center

The purpose of this study was to survey the quantity and quality of laboratory work conducted by Grade 11 and 12 biology students in British Columbia High Schools, to analyze student performance on laboratory based questions on Provincial examinations, and to examine the curriculum for recommended laboratory work. Examination and curriculum data…

Gardiner, Peter G.; Farragher, Pierce

240

Autonomous Robotics Laboratory: Hardware Demonstration of Cooperative Formation Control Laws  

Microsoft Academic Search

Autonomous robots are expected to be a key part of future space exploration, and for- mation control of robotic vehicles may be one autonomous task used in lunar or Martian exploration. This paper presents a cooperative control law to drive a group of autonomous robots to a desired formation. The cooperative control laws were implemented using the Autonomous Robotics Laboratory

Kristen E. Holmstrom; R oy Palacios; Brock Spratlen; Cynthia Ochoa; Lisa Warren; Lesley A. Weitz

241

The Development of An Undergraduate Laboratory for Control System Design  

Microsoft Academic Search

An undergraduate laboratory for control system design at Texas A&M University consisting of eight experimental stations, each equipped with a computer and control system analysis and design software, interface hardware and software, and several physical plants that will be used for control experiments is described. Among these plants are: 1) a toy called Capsela, 2) a carousel, 3) a coupled

Garng M. Huang; Li-Fang Fu; John Fleming

1993-01-01

242

Technical Justification for Radiation Controls at an Environmental Laboratory  

SciTech Connect

This paper describes the technical approach used to establish radiation protection controls over incoming radioactive materials to an environmental measurements laboratory at the Hanford Site. Conditions that would trigger internal dosimetry, posting.

DUPAQUIER, J.C.

2000-07-01

243

Towards automatic quantitative quality control for MRI  

NASA Astrophysics Data System (ADS)

Quality and consistency of clinical and research data collected from Magnetic Resonance Imaging (MRI) scanners may become suspect due to a wide variety of common factors including, experimental changes, hardware degradation, hardware replacement, software updates, personnel changes, and observed imaging artifacts. Standard practice limits quality analysis to visual assessment by a researcher/clinician or a quantitative quality control based upon phantoms which may not be timely, cannot account for differing experimental protocol (e.g. gradient timings and strengths), and may not be pertinent to the data or experimental question at hand. This paper presents a parallel processing pipeline developed towards experiment specific automatic quantitative quality control of MRI data using diffusion tensor imaging (DTI) as an experimental test case. The pipeline consists of automatic identification of DTI scans run on the MRI scanner, calculation of DTI contrasts from the data, implementation of modern statistical methods (wild bootstrap and SIMEX) to assess variance and bias in DTI contrasts, and quality assessment via power calculations and normative values. For this pipeline, a DTI specific power calculation analysis is developed as well as the first incorporation of bias estimates in DTI data to improve statistical analysis.

Lauzon, Carolyn B.; Caffo, Brian C.; Landman, Bennett A.

2012-02-01

244

Towards Automatic Quantitative Quality Control for MRI.  

PubMed

Quality and consistency of clinical and research data collected from Magnetic Resonance Imaging (MRI) scanners may become suspect due to a wide variety of common factors including, experimental changes, hardware degradation, hardware replacement, software updates, personnel changes, and observed imaging artifacts. Standard practice limits quality analysis to visual assessment by a researcher/clinician or a quantitative quality control based upon phantoms which may not be timely, cannot account for differing experimental protocol (e.g. gradient timings and strengths), and may not be pertinent to the data or experimental question at hand. This paper presents a parallel processing pipeline developed towards experiment specific automatic quantitative quality control of MRI data using diffusion tensor imaging (DTI) as an experimental test case. The pipeline consists of automatic identification of DTI scans run on the MRI scanner, calculation of DTI contrasts from the data, implementation of modern statistical methods (wild bootstrap and SIMEX) to assess variance and bias in DTI contrasts, and quality assessment via power calculations and normative values. For this pipeline, a DTI specific power calculation analysis is developed as well as the first incorporation of bias estimates in DTI data to improve statistical analysis. PMID:23087586

Lauzon, Carolyn B; Caffo, Brian C; Landman, Bennett A

2012-02-23

245

Report on preliminary control technology survey Jet Propulsion Laboratory, California Institute of Technology, Pasadena, California  

SciTech Connect

A preliminary control technology assessment conference and survey were held at the Jet Propulsion Laboratory (JPL) of the California Institute of Technology, Pasadena, CA., on November 4, 1981, as part of EPA/NIOSH joint effort to characterize indoor air quality in the electronics industry. The survey was conducted for a U.S. Environmental Protection Agency through an interagency agreement with the National Institute for Occupational Safety and Health. JPL has a Process Development Laboratory which is a research scale laboratory for the production of photovoltaic cells. Photovoltaic cells have many manufacturing steps in common with integrated circuits, which is the major thrust of this study.

Smith, R.K.; Rose, S.A.; Ungers, L.G.

1982-09-23

246

Combined Shewhart-cusum control chart for improved quality control in clinical chemistry.  

PubMed

We describe the adaptation of the decision limit cumulative sum method (cusum) to internal quality control in clinical chemistry. With the decision limit method, the cusum is interpreted against a numerical limit, rather than by use of a V-mask. The method can be readily implemented in computerized quality-control systems or manually on controls charts. We emphasize the manual application here and demonstrate how the technique can be implemented on existing Shewhart or Levey-Jennings control charts. This permits both cusum and Shewhart control rules to be used simultaneously on a single control chart and also minimizes the data calculations necessary for the cusum method. Computer simulation studies are used to determine the performance characteristics of several different cusum rules, alone and in combination with a Shewhart rule. These studies indicate that improvements in existing quality-control systems should be possible by addition of this simple cusum method and by use of a combined Shewhart-cusum control chart. This should be particularly advantageous when introducing the cusum method in laboratories with manual quality-control systems. PMID:902415

Westgard, J O; Groth, T; Aronsson, T; de Verdier, C H

1977-10-01

247

21 CFR 111.117 - What quality control operations are required for equipment, instruments, and controls?  

Code of Federal Regulations, 2011 CFR

... 2013-04-01 false What quality control operations are required...OPERATIONS FOR DIETARY SUPPLEMENTS Production and Process Control System: Requirements for Quality Control § 111.117 What quality control operations are...

2013-04-01

248

10 CFR 26.167 - Quality assurance and quality control.  

Code of Federal Regulations, 2010 CFR

...FITNESS FOR DUTY PROGRAMS Laboratories Certified by the Department... Each HHS-certified laboratory shall have a...must be interfaced with a laboratory information management system, or computer,...

2010-01-01

249

10 CFR 26.167 - Quality assurance and quality control.  

Code of Federal Regulations, 2010 CFR

...FITNESS FOR DUTY PROGRAMS Laboratories Certified by the Department... Each HHS-certified laboratory shall have a...must be interfaced with a laboratory information management system, or computer,...

2009-01-01

250

Analytical Chemistry Laboratory Quality Assurance Project Plan for the Transuranic Waste Characterization Program  

Microsoft Academic Search

This Quality Assurance Project Plan (QAPJP) specifies the quality of data necessary and the characterization techniques employed at the Idaho National Engineering Laboratory (INEL) to meet the objectives of the Department of Energy (DOE) Waste Isolation Pilot Plant (WIPP) Transuranic Waste Characterization Quality Assurance Program Plan (QAPP) requirements. This QAPJP is written to conform with the requirements and guidelines specified

Sailer

1996-01-01

251

Quality control procedures at Euskalmet data center  

NASA Astrophysics Data System (ADS)

The Basque Country Mesonet measures more than 130 000 observations daily from its 85 Automatic Weather Stations (AWS). It becomes clear that automated software is an indispensable tool for quality assurance (QA) of this mesoscale surface observing network. This work describes a set of experimental semi-automatic quality control (QC) routines that is applied at Euskalmet data center. It has paid special attention to level validation design and associated flags, as well as to the system outputs, which are used by meteorologist and maintenance staff.

Hernández, R.; Maruri, M.; Otxoa de Alda, K.; Egaña, J.; Gaztelumendi, S.

2012-06-01

252

Practicing Quality Control in a Bioanalytical Experiment  

NASA Astrophysics Data System (ADS)

The quality of analytical results frequently requires assessment, which has fostered treatment of this subject in a host of chemical books for students. Accordingly, new experiments need to be devised in order to help students adapt to it. This paper presents a straightforward exercise to demonstrate how quality control and the analysis of variance technique are implemented in practice. The exercise also is attractive because the analyte (chlorophyl) is determined in real samples (plants) that students can collect by themselves. In this way, they can realize the significance of sampling and learn how to do it properly.

Marcos, Juliana; Ríos, Angel; Valcárcel, Miguel

1995-10-01

253

Remote-controlled photonics laboratories for distance learning  

NASA Astrophysics Data System (ADS)

At Queensborough Community College, with the support of the National Science Foundation (Advanced Technological Education grant award #DUE - 9752061), we have addressed the issues of distance learning and laboratories and are adapting courses for our Laser and Fiber-Optics Technology Program for distance learning. The 'problem' of the laboratory is solved by remote-controlled laboratory equipment. We have completed the work on course materials in physical optics, lasers and fiber optics. Course materials include interactive multimedia textbooks and laboratory manuals along with the remote-controlled laboratory exercises. The remote-controlled exercises are 'real' experiments with 'real' data as opposed to simulations. The real nature of the exercises allows for the unexpected, which occurs in any laboratory situation. Remote-controlled laboratory exercises include interferometry, diffraction, polarization, acousto-optics, electro-optics, second harmonic generation, Q-switching, modelocking, thermal lensing, diode laser characteristics, laser principles, optical time domain reflectometry, coupling losses, wave division multiplexing and characteristics of fiber optic switches and couplers. As course materials were developed they were tested at a remote site, Suffolk County Community College.

Lieberman, David H.; Cheung, Tak D.

2002-05-01

254

National Research Laboratory Generic Project Quality Assurance Plan for research and development  

SciTech Connect

This Project Quality Assurance Plan (PQAP) sets forth the requirements for the National Research Laboratory's research Divisions' quality assurance programs to comply with the applicable criteria of 10CFR Part 50, Appendix B, ANSI/ASME NQA-1 and to meet the requirements of the Funding Agency's Quality Assurance Specification and the National Research Laboratory's QA Program for the projects that require a formal Quality Assurance plan. The requirements of this plan apply to project activities that affect the quality and reliability/creditability of research, development, and investigative data and documentation. These activities include the functions of attaining quality objectives and assuring that an appropriate quality assurance program scope is established. The scope of activities affecting quality include personnel training and qualifications; designing; purchasing; material handling and storage; surveillance, testing, and auditing; R and D investigative activities and documentation; deficiencies; corrective actions; and QA recordkeeping.

Bain, E.E.; Hinckley, R.L.

1986-09-01

255

Quality assurance consideration for cement-based grout technology programs at Oak Ridge National Laboratory  

SciTech Connect

Oak Ridge National Laboratory has developed and is continuing to refine a method of immobilizing low-level radioactive liquid wastes by mixing them with cementitious dry-solid blends. A quality assurance program is vital to the project because Nuclear Regulatory Commission (NRC), Environmental Protection Agency (EPA) and state environmental regulations must be demonstrably met (the work must be defensible in a court of law). The end result of quality assurance (QA) is, by definition, a product of demonstrable quality. In the laboratory, this entails traceability, repeatability, and credibility. This paper describes the application of QA in grout technology development at Oak Ridge National Laboratory.

McDaniel, E.W.; Tallent, O.K.; Sams, T.L.; Delzer, D.B.

1987-01-01

256

Color metric for production quality control  

Microsoft Academic Search

A real-time color quality control metric for planar surfaces has been developed. This is a differencing method that compares the color histogram of a test object with that of a standard obtained off-line. To reduce computational effort, three 1D histograms are formed by projecting the reference color histogram on to its principal axes. A metric value for each of the

Anthony J. McCollum; Andrew K. Forrest

1999-01-01

257

Sandia National Laboratories, California Air Quality Program : annual report.  

SciTech Connect

The annual program report provides detailed information about all aspects of the SNL/CA Air Quality Program. It functions as supporting documentation to the SNL/CA Environmental Management System Program Manual. The program report describes the activities undertaken during the past year, and activities planned in future years to implement the Air Quality Program, one of six programs that supports environmental management at SNL/CA.

Shih, Richard (ERM, Walnut Creek, CA); Gardizi, Leslee P.

2007-05-01

258

Quality assurance\\/quality control in waste site characterization and remedial action: Final report, December 1986June 1987  

Microsoft Academic Search

This report details efforts to date to advance the state of the art of Quality Assurance\\/Quality Control (QA\\/QC) in waste site characterization and remedial action. The report is organized into three sections. The first section provides recommendations on the unification of the two widely used and accepted QA\\/QC programs: the US Environmental Protection Agency Contract Laboratory program (USEPACLP) and the

M. P. Maskarinec; S. K. Holladay

1987-01-01

259

Dynamics of Spacecraft Control Laboratory Experiment (SCOLE) Slew Maneuvers.  

National Technical Information Service (NTIS)

This is the first of two reports on the dynamics and control of slewing maneuvers of the NASA Spacecraft Control Laboratory Experiment (SCOLE). In this report, the dynamics of slewing maneuvers of SCOLE are developed in terms of an arbitrary maneuver abou...

Y. P. Kakad

1987-01-01

260

Faa Air Traffic Control Simulation Laboratory at Nafec  

Microsoft Academic Search

One of the most effective tools for use in air traffic control experimentation, evaluation, and systems studies is the Simulation Laboratory of the Federal Aviation Agency's National Facilities Experimental Center (NAFEC) located at Atlantic City, New Jersey. Currently at NAFEC, systems combining analog and digitalsimulated radar target generation techniques are employed to provide the most comprehensive air traffic control simulation

Thomas S. Wonnell

1966-01-01

261

Research on quarantine model of the product quality characteristics based on immune quality control  

Microsoft Academic Search

In order to solve the prevention control problem in quality system, for the similarity with the manufacturing process operation, the biological immune mechanism is applied into the quality control process. Firstly the connotation of the immune quality management and controlling is discussed in this paper, then based on the immunity network study of the immune system, the quality immunity network

Xianlin Ren; Genbao Zhang

2010-01-01

262

Application of the Environmental Protection Agency`s data quality objective process to environmental monitoring quality control  

SciTech Connect

The United States Environmental Protection Agency`s (EPA) Data Quality Objectives (DQO) process was applied to two environmental monitoring networks for the purpose of optimizing field quality control sampling to give the highest quality monitoring data with minimal impact on resources. The DQO process, developed primarily to aid in cleanup and restoration activities, is a systematic approach to designing sampling, and analysis programs with improved efficiency, cost savings, and measureable and traceable data quality. The two monitoring- networks studied had not been subjected to the systematic review and analysis of the DQO process defined by the EPA. The two monitoring networks studied had relied upon field duplicates or replicates as the main source of field quality control data. Sometimes, both duplicate and routine sample were analyzed by the same analytical laboratory; at other times they were analyzed by different laboratories. This study identified some potential inconsistencies between analytical data and reporting limits from two different laboratories. Application of the EPA DQO process resulted in recommendations for changes in the field quality control sampling program, allowed new insight into the monitoring data, and raised several issues that should be the subject of further investigation.

Garcia, L.M.

1995-11-01

263

Air quality management in the WHO European Region--results of a quality assurance and control programme on air quality monitoring (1994-2004).  

PubMed

Since the last decade the WHO Collaborating Centre for Air Quality Management and Air Pollution Control, Berlin, Germany, operates a quality assurance and control (QA/QC) programme on air quality monitoring in the WHO European Region. As main activity Intercomparison workshops have been established for air monitoring network laboratories on a regular basis to harmonise air quality measurements, analysis and calibration techniques. 36 air hygiene laboratories of public health and environmental institutions of 24 countries participated in twelve Intercomparisons between 1994 and 2004. The majority was carried out for NO, NO(2), SO(2) and O(3). The results were predominantly satisfactory for automatic methods. The results of manual methods were mainly in a good, and for several concentration levels partly very good accordance with the data obtained by the monitors. PMID:18234339

Mücke, Hans-Guido

2008-01-29

264

10 CFR 26.167 - Quality assurance and quality control.  

Code of Federal Regulations, 2013 CFR

...laboratory, which may be conducted unannounced during any hours of operation of the laboratory. (g) Accuracy. Volumetric pipettes and measuring devices must be certified for accuracy or be checked by gravimetric, colorimetric, or other verification...

2013-01-01

265

Protocol Development, Treatment Fidelity, Adherence to Treatment, and Quality Control  

PubMed Central

Occupational therapy leaders have emphasized the importance of intervention effectiveness research. The CONSORT and TREND checklists have been suggested as useful tools for reporting the results of randomized and nonrandomized studies, respectively. Despite such recommendations, research protocols and reports continue to underutilize the available tools, a situation reflecting limited resources for and experience with the conduct of effectiveness research. To address this issue, and using the CONSORT statement to structure the analysis, this article discusses strategies for optimization of protocol development, treatment fidelity, adherence to treatment, and quality control. We recommend several approaches to increase the quality of research throughout these various processes. Examples of implementation from our laboratory provide evidence of the utility of these strategies.

Page, Stephen J.

2013-01-01

266

Application of sigma metrics for the assessment of quality assurance in clinical biochemistry laboratory in India: a pilot study.  

PubMed

Ensuring quality of laboratory services is the need of the hour in the field of health care. Keeping in mind the revolution ushered by six sigma concept in corporate world, health care sector may reap the benefits of the same. Six sigma provides a general methodology to describe performance on sigma scale. We aimed to gauge our laboratory performance by sigma metrics. Internal quality control (QC) data was analyzed retrospectively over a period of 6 months from July 2009 to December 2009. Laboratory mean, standard deviation and coefficient of variation were calculated for all the parameters. Sigma was calculated for both the levels of internal QC. Satisfactory sigma values (>6) were elicited for creatinine, triglycerides, SGOT, CPK-Total and Amylase. Blood urea performed poorly on the sigma scale with sigma <3. The findings of our exercise emphasize the need for detailed evaluation and adoption of ameliorative measures in order to effectuate six sigma standards for all the analytical processes. PMID:22468038

Singh, Bhawna; Goswami, Binita; Gupta, Vinod Kumar; Chawla, Ranjna; Mallika, Venkatesan

2010-11-16

267

Science Laboratories and Indoor Air Quality in Schools. Technical Bulletin.  

ERIC Educational Resources Information Center

Some of the issues surrounding the indoor air quality (IAQ) problems presented by science labs are discussed. Described are possible contaminants in labs, such as chemicals and biological organisms, and ways to lessen accidents arising from these sources are suggested. Some of the factors contributing to comfort, such as temperature levels, are…

Jacobs, Bruce W.

268

Science Laboratories and Indoor Air Quality in Schools. Technical Bulletin.  

ERIC Educational Resources Information Center

|Some of the issues surrounding the indoor air quality (IAQ) problems presented by science labs are discussed. Described are possible contaminants in labs, such as chemicals and biological organisms, and ways to lessen accidents arising from these sources are suggested. Some of the factors contributing to comfort, such as temperature levels, are…

Jacobs, Bruce W.

269

[The hemolysis index as quality indicator for extra-laboratory part of preanalytical phase].  

PubMed

The article considers the new indicator of quality - percentage of samples with hemolysis of free hemoglobin in blood serum lesser than 500 mg/l that corresponds the index of hemolysis lesser than 50 measured using analyzer VITROS 5.1FS (Ortho-clinical diagnostics, USA). The indicator basically is related to quality of implementation of extra-laboratory section of pre-analytical stage of laboratory analysis namely drawing and transportation of blood. This indicator is especially valuable for laboratories charged with organization of samples drawing and transportation at particular territory. The first attempt is made to determine the requirements to quality according this indicator. The optimal level of quality, is the percentage of samples with hemolysis index less than 50 is lower 6.4%. acceptable - 6.4%-8.6%, minimal - 8.7% - 10.9%. The percentage af samples more than 10.9% corresponds to unacceptable level of quality. PMID:23305024

Moshkin, A V

2012-11-01

270

The World Health Organization African region laboratory accreditation process: improving the quality of laboratory systems in the African region.  

PubMed

Few developing countries have established laboratory quality standards that are affordable and easy to implement and monitor. To address this challenge, the World Health Organization Regional Office for Africa (WHO AFRO) established a stepwise approach, using a 0- to 5-star scale, to the recognition of evolving fulfillment of the ISO 15189 standard rather than pass-fail grading. Laboratories that fail to achieve an assessment score of at least 55% will not be awarded a star ranking. Laboratories that achieve 95% or more will receive a 5-star rating. This stepwise approach acknowledges to laboratories where they stand, supports them with a series of evaluations to use to demonstrate improvement, and recognizes and rewards their progress. WHO AFRO's accreditation process is not intended to replace established ISO 15189 accreditation schemes, but rather to provide an interim pathway to the realization of international laboratory standards. Laboratories that demonstrate outstanding performance in the WHO-AFRO process will be strongly encouraged to enroll in an established ISO 15189 accreditation scheme. We believe that the WHO-AFRO approach for laboratory accreditation is affordable, sustainable, effective, and scalable. PMID:20716795

Gershy-Damet, Guy-Michel; Rotz, Philip; Cross, David; Belabbes, El Hadj; Cham, Fatim; Ndihokubwayo, Jean-Bosco; Fine, Glen; Zeh, Clement; Njukeng, Patrick A; Mboup, Souleymane; Sesse, Daniel E; Messele, Tsehaynesh; Birx, Deborah L; Nkengasong, John N

2010-09-01

271

Mammographic equipment, technique, and quality control  

SciTech Connect

The most important improvements in mammographic technique were the introduction of single- or double-emulsion high-contrast film-screen combinations for mammography, the use of a specially designed low-kilovoltage Bucky grid to reduce scattered radiation, and the introduction of smaller focal spots to improve imaging geometry. Magnification techniques, especially the spot-film technique, yields clearer delineation of high-contrast microcalcifications. Dedicated mammographic equipment with specially designed x-ray tubes is necessary for modern high-quality mammography. However, in many modern mammographic units, the automatic exposure controller still fails to provide appropriate and constant optical film density over a wide range of tissue thickness and absorption. Extended-cycle processing of single-emulsion mammographic films can yield better image contrast and reduce exposure by up to 30%. Exposure times of less than 1 second are recommended to avoid the unnecessary higher doses caused by longer exposure times and reciprocity law failure. The wide dynamic range in mammography can be reduced by a beam equalization filter, and thus be better adapted to the decreased latitude of modern high-contrast mammographic screen-film systems. Mammographic film reading (detection of subtle microcalcifications) can be facilitated by modern computer evaluation of previously digitized mammograms. Standardization and assurance of image quality have been major challenges in the technical development of mammography. Different technical and anthropomorphic phantoms have been designed to measure and compare practical image quality. Detailed quality control measures have been developed. The benefit of a single or annual screening mammography, calculated in gained life expectancy, by far outweighs the relative risk for radiation-induced breast cancer. 22 references.

Friedrich, M.A. (Urban Hospital, Berlin (West Germany))

1991-08-01

272

Research on dynamic intelligent control system of grinding quality  

Microsoft Academic Search

How to solve the problems of monitoring dynamic and variable quality variation, diagnosing the abnormal variation and adjusting the process at the right moment, is a difficult problem that modern manufacturing enterprise faces challenges in process of grinding quality control. A dynamic, intelligent control model of grinding quality was put forward, which integrated quality prevention, analysis, diagnosis and adjustment, in

Jiaqi Jin; Xingyu Jiang; Xinmin Zhang; Wanshan Wang

2010-01-01

273

Five Librarians Talk about Quality Control and the OCLC Database.  

ERIC Educational Resources Information Center

|Five librarians considered authorities on quality cataloging in the OCLC Online Union Catalog were interviewed to obtain their views on the current level of quality control in the OCLC database, the responsibilities of OCLC and individual libraries in improving the quality of records, and the consequences of quality control problems. (CLB)|

Helge, Brian; And Others

1987-01-01

274

Understanding Video Quality and its use in Feedback Control  

Microsoft Academic Search

There has been an increased interest in adaptive video quality control and dynamically adjusting the output video bit rate based on the status of the network. However, network-level performance parameters cannot accurately reflect the video quality perceived by the end users. Our goal is to investigate an adaptive perceptual video quality control mechanism based on an application-level perceptual video quality

Xiaoxiang Lu; Ramon Orlando Morando; Magda El Zarki

2002-01-01

275

The operation, quality and costs of a district hospital laboratory service in Malawi  

Microsoft Academic Search

Laboratory services are run down in many low-income countries, severely constraining their input to patient care and disease surveillance. There are few data about the quality and cost of individual components of the laboratory service in poorer countries, yet this information is essential if optimal use is to be made of scarce resources. Staff time, range of tests, workload, and

C. J. F. Mundy; I. Bates; W. Nkhomal; K. Floyd; G. Kadewele; M. Ngwira; A. Khuwi; S. B. Squire; C. F. Gilks

2003-01-01

276

Application of Traditional Clinical Pathology Quality Control Techniques to Molecular Pathology  

PubMed Central

Many molecular diagnostic laboratories have evolved from research laboratories, initially performing low numbers of homebrew assays, but many laboratories now perform more kit-based assays, with ever increasing test volumes. One such assay is assessment of bone marrow transplantation engraftment. Allogeneic bone marrow transplantation is performed primarily in the treatment of hematological malignancies. Monitoring of engraftment was traditionally evaluated using minisatellites (variable number tandem repeats) and Southern blotting, but most laboratories now use Food and Drug Administration-cleared microsatellite (short tandem repeats) kits to assess the extent of engraftment. With the increase in equipment reliability, the use of kit-based assays, and the desire to provide the highest quality clinical data, we began applying traditional clinical pathology quality control tools to the molecular diagnostics laboratory. In this study, we demonstrate this approach using a microsatellite-based bone marrow engraftment assay. We analyzed control samples (pure and mixed) for two different microsatellites to establish quality control parameters and constructed Levey-Jennings charts to monitor both the precision and accuracy of this assay. By incorporating these tools into an overall quality assurance program, a laboratory can identify systematic errors and perform corrective actions before actual assay failure, thereby improving the quality of patient care.

Liang, Shu-Ling; Lin, Ming-Tseh; Hafez, Michael J.; Gocke, Christopher D.; Murphy, Kathleen M.; Sokoll, Lori J.; Eshleman, James R.

2008-01-01

277

Application of traditional clinical pathology quality control techniques to molecular pathology.  

PubMed

Many molecular diagnostic laboratories have evolved from research laboratories, initially performing low numbers of homebrew assays, but many laboratories now perform more kit-based assays, with ever increasing test volumes. One such assay is assessment of bone marrow transplantation engraftment. Allogeneic bone marrow transplantation is performed primarily in the treatment of hematological malignancies. Monitoring of engraftment was traditionally evaluated using minisatellites (variable number tandem repeats) and Southern blotting, but most laboratories now use Food and Drug Administration-cleared microsatellite (short tandem repeats) kits to assess the extent of engraftment. With the increase in equipment reliability, the use of kit-based assays, and the desire to provide the highest quality clinical data, we began applying traditional clinical pathology quality control tools to the molecular diagnostics laboratory. In this study, we demonstrate this approach using a microsatellite-based bone marrow engraftment assay. We analyzed control samples (pure and mixed) for two different microsatellites to establish quality control parameters and constructed Levey-Jennings charts to monitor both the precision and accuracy of this assay. By incorporating these tools into an overall quality assurance program, a laboratory can identify systematic errors and perform corrective actions before actual assay failure, thereby improving the quality of patient care. PMID:18258922

Liang, Shu-Ling; Lin, Ming-Tseh; Hafez, Michael J; Gocke, Christopher D; Murphy, Kathleen M; Sokoll, Lori J; Eshleman, James R

2008-02-07

278

External Quality Assessment of Molecular Typing of Staphylococcus aureus Isolates by a Network of Laboratories  

PubMed Central

A network of laboratories designated Centres for Molecular Diagnosis was funded in 2000 by Belgian National Health Insurance to provide clinically relevant molecular diagnostic tests. These included typing of nosocomial pathogens as a service to local hospital infection control programs. Two external quality assessment (EQA) surveys were performed in 2001 and 2003 to evaluate the proficiencies of the laboratories at Staphylococcus aureus typing. EQA panels included S. aureus isolates with either indistinguishable, clonally related, or unrelated pulsed-field gel electrophoresis (PFGE) patterns. A hypothetical hospital outbreak problem was also submitted for analysis. Typeability, reproducibility, discrimination (D) index, and epidemiological concordance were evaluated. Ten centers participated in each survey. Seven centers performed PFGE analysis, while others used repetitive-element or randomly amplified polymorphic DNA PCR, amplified fragment length polymorphism, or spa typing. Full typeability (100%) was achieved by all centers, and all but one showed 100% reproducibility. Discrimination was appropriate (D index, ?96%) for centers performing PFGE analysis but not for all those using other methods (D index range, 72% to 97%). Correct answers to the epidemiological questions were provided by 7/10 and 10/10 centers in 2001 and 2003, respectively. Individual feedback of results was provided to each center together with specific technical recommendations for improving performance. Our findings indicate that surveys of lab proficiency are useful for validation and optimization of molecular typing services to local hospital infection control programs.

Deplano, A.; De Mendonca, R.; De Ryck, R.; Struelens, M. J.

2006-01-01

279

BK060064, Verisure Pro HBV DNA External Quality Control  

Center for Biologics Evaluation and Research (CBER)

Text Version... 1. Trade Name VeriSure Pro HBV DNA External Quality Control 2. Common Name AcroMetrix HBV External Quality Control ... More results from www.fda.gov/downloads/biologicsbloodvaccines/bloodbloodproducts

280

21 CFR 640.56 - Quality control test for potency.  

Code of Federal Regulations, 2011 CFR

...ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS ADDITIONAL STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS Cryoprecipitate § 640.56 Quality control test for potency. (a) Quality control tests...

2011-04-01

281

VeriSure Pro HBV DNA External Quality Control  

Center for Biologics Evaluation and Research (CBER)

... VeriSure Pro HBV DNA External Quality Control. Applicant: AcroMetrix Corporation. ... Product: VeriSure Pro HBV DNA External Quality Control. ... More results from www.fda.gov/biologicsbloodvaccines/bloodbloodproducts/approvedproducts

282

[Quality control in aspiration biopsy cytology].  

PubMed

Comparison and quality control of our experience of thyroid cytology (784 samples) and breast cytology (1,202 samples) were reported. False positive rate and other parameters were superior in breast cytology than thyroid. It may be due to the fact that cytological diagnostic criteria for follicular thyroid carcinoma from follicular adenoma is not established yet. More suspicious diagnosis in thyroid than breast also give low incidence of malignancy in thyroid suspicious diagnosis. As recommended by a guideline for both thyroid and breast cytology from the Papanicolaou society et al, conservative handling and protective diagnosis may help to reduce false positive and false negative rates. PMID:9564760

Kakudo, K; Taniguchi, E; Nakamura, Y; Yokoi, T; Nunobiki, O; Kaname, A; Sakurai, T

1998-03-01

283

A controllable laboratory stock market for modeling real stock markets  

NASA Astrophysics Data System (ADS)

Based on the different research approaches, econophysics can be divided into three directions: empirical econophysics, computational econophysics, and experimental econophysics. Because empirical econophysics lacks controllability that is needed to study the impacts of different external conditions and computational econophysics has to adopt artificial decision-making processes that are often deviated from those of real humans, experimental econophysics tends to overcome these problems by offering controllability and using real humans in laboratory experiments. However, to our knowledge, the existing laboratory experiments have not convincingly reappeared the stylized facts (say, scaling) that have been revealed for real economic/financial markets by econophysicists. A most important reason is that in these experiments, discrete trading time makes these laboratory markets deviated from real markets where trading time is naturally continuous. Here we attempt to overcome this problem by designing a continuous double-auction stock-trading market and conducting several human experiments in laboratory. As an initial work, the present artificial financial market can reproduce some stylized facts related to clustering and scaling. Also, it predicts some other scaling in human behavior dynamics that is hard to achieve in real markets due to the difficulty in getting the data. Thus, it becomes possible to study real stock markets by conducting controlled experiments on such laboratory stock markets producing high frequency data.

An, Kenan; Li, Xiaohui; Yang, Guang; Huang, Jiping

2013-10-01

284

Assessing and controlling the quality of a project end product: the earned quality method  

Microsoft Academic Search

Quality is achieved to the extent that a project end product meets the client's needs and expectations. This paper addresses the fundamental issues relating to the periodic assessment and control of the quality of the end product of a project. The proposed earned quality method (EQM) enables project managers to assess and control the quality of the end product throughout

Jean Paul Paquin; Jean Couillard; Dominique J. Ferrand

2000-01-01

285

Laboratory and Field Audits as Part of the EPA (Environmental Protection Agency) Hazardous Waste Engineering Research Laboratory (HWERL) Quality Assurance Program,  

National Technical Information Service (NTIS)

Audits are an important and integral part of the EPA Hazardous Waste Engineering Research Laboratory (HWERL) Quality Assurance (QA) Program. As part of the overall QA program, audits are used to determine contractor compliance with quality assurance plans...

W. B. Blackburn G. F. Simes

1988-01-01

286

Electronic Nose for Quality Control of Colombian Coffee Through the Detection of Defects in ``Cup Tests''  

NASA Astrophysics Data System (ADS)

This article presents a preliminary study on the analysis of samples of Colombian coffee for the detection and classification of defects (i.e. using ``Cup Tests''), which was conducted in Almacafé quality control laboratory Almacafé in Cúcuta, Colombia). The results obtained show the application of an Electronic Nose (EN), called ``A-NOSE,'' used in the coffee sector for the cupping tests. The results show that e-nose technology can be a useful tool as quality control of coffee grain.

Rodríguez, Juan C.; Duran, Cristhian M.; Reyes, Adriana X.

2009-05-01

287

An automated hematology laboratory with computer-controlled robotics.  

PubMed

A highly automated hematology laboratory environment is described that has conveyance systems to move bar-coded specimens from one station ("workcell") to another, robotic handling devices to load and unload hematology analyzers, and a hematology workstation. Computer systems monitor the process and equipment, track the specimen, manage inventory, and interpret patient results. When a specimen arrives at the laboratory, the bar-code determines which workcell the specimen should go to for testing. Each specimen is handled individually and in real-time. Hematology specimens are routed to a workcell of Coulter STKS analyzers where complete blood counts with five-part leukocyte differentials are performed under full robotic control. The entire process is managed by a real-time Windows-based process control system that interacts with a networked laboratory information system. The hematology workstation is being evaluated for interpretive results reporting and to determine follow-up testing. PMID:8591282

Diamond, L W; Nguyen, D T; Sheridan, B L; Strul, M; Bailey, K; Bak, A

1995-01-01

288

Cross-connection control of the potable water lines at Oak Ridge National Laboratory  

Microsoft Academic Search

A 1991 independent U.S. Department of Energy (DOE) audit of Oak Ridge National Laboratory (ORNL) identified the need for establishing a cross-connection control program for the potable and nonpotable water systems at the facility. An informal cross-connection policy had been in place for some time, but the formal implementation of a cross-connection program brought together individuals from the Quality Engineering

1996-01-01

289

A Method Product Quality Control between Enterprises and its Implementation  

Microsoft Academic Search

Along with the intensification of global competition and the complexity of manufacturing products, the cooperation among enterprises becomes more closely, and the range of quality control extends from internal to the external enterprises. To the demand of product quality control among enterprises, based on holon theory, the product quality control holonic structure for extended enterprises is constructed by the similarity

Jie Tian; Jianxin Lv

2010-01-01

290

Product Quality Control Method for Extended Enterprises Based on Holonic  

Microsoft Academic Search

Based on holons theory, the product quality control holonic structure for extended enterprises is constructed by the similarity characteristic of quality control function extended enterprises. In the structure, the quality control holons that has autonomy and cooperation ability are established, and by the analysis of holon cooperation operation, by means of the definition and description the cooperation relations among holons,

Xiaolin Xu

2009-01-01

291

Quality control parameters for Tamra (copper) Bhasma  

PubMed Central

Background: Metallic Bhasmas are highly valued and have their own importance in Ayurvedic formulations. To testify the Bhasmas various parameters have been told in Rasashastra classics. Tamra Bhasma (TB) with its different properties is used in the treatment of various diseases is quiet famous among the Ayurvedic physicians (Vaidyas). Objectives: The present study was carried out to set up the quality control parameters for the TB by making the use of classical tests along with advanced analytical tools. Settings and Design: Copper wire taken for the preparation of Bhasma was first analyzed for its copper content and then subjected to Shodhana, Marana and Amrutikarana procedures as per the classical references. Final product complied with all the classical parameters like Rekhapurnatwa, Varitaratwa etc. Materials and Methods: After complying with these tests TB was analyzed by advanced analytical techniques like particle size distribution (PSD) analysis, scanning electron microscopy (SEM), and inductive coupled plasma spectrometry (ICP). Results: PSD analysis of TB showed volumetric mean diameter of 28.70 ?m, 50% of the material was below 18.40 ?m size. Particle size less than 2?m were seen in SEM. 56.24 wt % of copper and 23.06 wt % of sulphur was found in ICP-AES. Heavy metals like cadmium, selenium were not detected while others like arsenic, lead and mercury were present in traces. Conclusions: These observations could be specified as the quality control parameters conforming to all the classical tests under the Bhasma Pariksha.

Jagtap, Chandrashekhar Yuvaraj; Prajapati, Pradeepkumar; Patgiri, Biswajyoti; Shukla, Vinay J.

2012-01-01

292

Quality control of laser tailor welded blanks  

NASA Astrophysics Data System (ADS)

Tailor welded blanks were widely used in the automobile industry for their special advantages. A combination of different materials, thickness, and coatings could be welded together to form a blank for stamping car body panels. With the gradually growing consciousness on safety requirement of auto body structural, the business of laser tailor welded blanks is developing rapidly in China. Laser tailor welded blanks were just the semi products between steel factory and automobile manufacturers. As to the laser welding defects such as convexity and concavity, automobile industry had the strict requirement. In this paper, quality standard on laser tailor welded blanks were discussed. As for the production of laser tailor welded blanks, online quality control of laser tailor welded blanks was introduced. The image processing system for welding laser positioning and weld seam monitoring were used in the production of laser tailor welded blanks. The system analyzes images from the individual cameras and transmits the results to the machine control system via a CAN bus.

Yan, Qi

2008-03-01

293

Millikan's Oil-Drop Experiment as a Remotely Controlled Laboratory  

ERIC Educational Resources Information Center

|The Millikan oil-drop experiment, to determine the elementary electrical charge e and the quantization of charge Q = n [middle dot] e, is an essential experiment in physics teaching but it is hardly performed in class for several reasons. Therefore, we offer this experiment as a remotely controlled laboratory (RCL). We describe the interactivity…

Eckert, Bodo; Grober, Sebastian; Vetter, Martin; Jodl, Hans-Jorg

2012-01-01

294

External quality assurance performance of clinical research laboratories in sub-saharan Africa.  

PubMed

Patient Safety Monitoring in International Laboratories (JHU-SMILE) is a resource at Johns Hopkins University that supports and monitors laboratories in National Institutes of Health-funded international clinical trials. To determine the impact of the JHU-SMILE quality assurance scheme in sub-Saharan African laboratories, we reviewed 40 to 60 months of external quality assurance (EQA) results of the College of American Pathologists (CAP) in these laboratories. We reviewed the performance of 8 analytes: albumin, alanine aminotransferase, creatinine, sodium, WBC, hemoglobin, hematocrit, and the human immunodeficiency virus antibody rapid test. Over the 40- to 60-month observation period, the sub-Saharan laboratories had a 1.63% failure rate, which was 40% lower than the 2011 CAP-wide rate of 2.8%. Seventy-six percent of the observed EQA failures occurred in 4 of the 21 laboratories. These results demonstrate that a system of remote monitoring, feedback, and audits can support quality in low-resource settings, even in places without strong regulatory support for laboratory quality. PMID:23086773

Amukele, Timothy K; Michael, Kurt; Hanes, Mary; Miller, Robert E; Jackson, J Brooks

2012-11-01

295

External Quality Assessment Scheme for reference laboratories - review of 8 years' experience.  

PubMed

We describe an External Quality Assessment Scheme (EQAS) intended for reference (calibration) laboratories in laboratory medicine and supervised by the Scientific Division of the International Federation of Clinical Chemistry and Laboratory Medicine and the responsible Committee on Traceability in Laboratory Medicine. The official EQAS website, RELA (www.dgkl-rfb.de:81), is open to interested parties. Information on all requirements for participation and results of surveys are published annually. As an additional feature, the identity of every participant in relation to the respective results is disclosed. The results of various groups of measurands (metabolites and substrates, enzymes, electrolytes, glycated hemoglobins, proteins, hormones, thyroid hormones, therapeutic drugs) are discussed in detail. The RELA system supports reference measurement laboratories preparing for accreditation according to ISO 17025 and ISO 15195. Participation in a scheme such as RELA is one of the requirements for listing of the services of a calibration laboratory by the Joint Committee on Traceability in Laboratory Medicine. PMID:23327864

Kessler, Anja; Siekmann, Lothar; Weykamp, Cas; Geilenkeuser, Wolf Jochen; Dreazen, Orna; Middle, Jonathan; Schumann, Gerhard

2013-05-01

296

AUDILAB: quality audit simulation to prepare biomedical testing laboratories for accreditation.  

PubMed

In order to prepare biomedical laboratories for accreditation a quality audit simulator has been developed. By means of a dialogue with the laboratory, AUDILAB simulates the process by which the auditor identifies deviations or assesses conformity to the standard. AUDILAB is based on a knowledge processing system accessible via Minitel (French videotex terminal). With reference to the EN 45001 standard which is the European standard concerning the "General criteria for the operation of testing laboratories", it provides an assessment of the laboratory's degree of conformity and prompts it to take corrective action. PMID:7640913

Garnerin, P; Brai, A; Lelièvre, H; Tuffery, G

1995-03-01

297

Direct product quality control for energy efficient climate controlled transport of agro-material  

Microsoft Academic Search

A (model-based) Product Quality Controller is presented for climate controlled operations involving agro-material, such as storage and transport. This controller belongs to the class of Model Predictive Controllers and fits in a previously developed hierarchical control structure. The new Product Quality Controller rejects disturbances and tracks the product quality by means of the product responses respiration and fermentation. To achieve

G. J. C. Verdijck; H. A. Preisig; G. van Straten

2005-01-01

298

Sandia National Laboratories Advanced Simulation and Computing (ASC) software quality plan : ASC software quality engineering practices Version 3.0.  

SciTech Connect

The purpose of the Sandia National Laboratories (SNL) Advanced Simulation and Computing (ASC) Software Quality Plan is to clearly identify the practices that are the basis for continually improving the quality of ASC software products. Quality is defined in the US Department of Energy/National Nuclear Security Agency (DOE/NNSA) Quality Criteria, Revision 10 (QC-1) as 'conformance to customer requirements and expectations'. This quality plan defines the SNL ASC Program software quality engineering (SQE) practices and provides a mapping of these practices to the SNL Corporate Process Requirement (CPR) 001.3.6; 'Corporate Software Engineering Excellence'. This plan also identifies ASC management's and the software project teams responsibilities in implementing the software quality practices and in assessing progress towards achieving their software quality goals. This SNL ASC Software Quality Plan establishes the signatories commitments to improving software products by applying cost-effective SQE practices. This plan enumerates the SQE practices that comprise the development of SNL ASC's software products and explains the project teams opportunities for tailoring and implementing the practices.

Turgeon, Jennifer L.; Minana, Molly A.; Hackney, Patricia; Pilch, Martin M.

2009-01-01

299

Quality assurance and quality control in monitoring programs  

Microsoft Academic Search

There are three general characteristics of the data to be collected in a monitoring program that should be met in order to maximize the use and value of the data: the data quality should be known, the data type and quality should be consistent and comparable, and the data should be available and accessible. Potential problems with each of these

William J. Shampine

1993-01-01

300

Passive ventilation for residential air quality control  

SciTech Connect

Infiltration has long served the residential ventilation needs in North America. In Northern Europe it has been augmented by purpose-provided natural ventilation systems--so-called passive ventilation systems--to better control moisture problems in dwellings smaller than their North American counterparts and in a generally wetter climate. The growing concern for energy consumption, and the environmental impacts associated with it, has however led to tighter residential construction standards on both continents and as a result problems associated with insufficient background ventilation have surfaced. Can European passive ventilation systems be adapted for use in North American dwellings to provide general background ventilation for air quality control? This paper attempts to answer this question. The configuration, specifications and performance of the preferred European passive ventilation system--the passive stack ventilation (PSV) system--will be reviewed; innovative components and system design strategies recently developed to improve the traditional PSV system performance will be outlined; and alternative system configurations will be presented that may better serve the climatic extremes and more urban contexts of North America. While these innovative and alternative passive ventilation systems hold great promise for the future, a rational method to size the components of these systems to achieve the control and precision needed to meet the conflicting constraints of new ventilation and air tightness standards has not been forthcoming. Such a method will be introduced in this paper and an application of this method will be presented.

Axley, J.

1999-07-01

301

[Evaluating an internal quality control procedure: application to multidimensional control].  

PubMed

Internal quality control keeps in constant evolution in the industrial world. Introducing in clinical chemistry new QC methods derived from the industrial practice raises the point of the means for their evaluation. The main evaluation criteria are discussed in this paper. The importance of ARL (average run length) as a key-criterion of the efficiency of a quality control procedure is stressed. These principles were applied to the multivariate approach of multilevel control with the Hotelling's T2. This method led to a better detection of random errors than the independently managed conventional Shewhart (Levey- Jennings) charts. Applied to systematic errors, both methods gave similar results with a certain lack of sensitivity. However the multivariate method can be sensitised using EWMA (exponentially weighted moving average), a method specific for improved bias detection. EWMA efficiency outperforms that of the older systems of rules. Moreover, in any kind of error, multivariate approach secures a well-defined false rejection rate, whereas this rate is dependant on unknown inter-level correlation coefficients in conventional QC. PMID:12368148

Marquis, P; Masseyeff, R

302

Control fisico quimico de calidad del HIPURAN-(sup 131)I. (Chemical and physical quality control of the HIPPURAN-(sup 131)I).  

National Technical Information Service (NTIS)

Some physico-chemical methods for analytical control of Hippuran-(sup 131)I are compared. The most convenient to applicate in hospitals and in more specialized quality control laboratories are recommended. The quality of Hippuran-(sup 131)I produced by IS...

J. Morin Zorilla E. Olive M. Isaac J. Cruz

1989-01-01

303

Scanning means for radiational quality control  

SciTech Connect

This paper analyzes the scanning means for radiational quality control with synthesis of the results in the form of a TV image adequate to the radiational image of the x-rayed object. A method is presented of calculation of the sensitivity of the scanning x-ray apparatus in the range of anode voltages of the x-ray tube 100-240 kV for the thicknesses of steel 1-40 mm. It shows the dependence of the sensitivity of the apparatus on the radiant energy, the size of the scanning element, and the accumulation time. Data are given concerning samples of scanning apparatus made by firms outside of the USSR. The ranges of the most effective utilization of the scanning apparatus are recommended.

Kanter, B.M.; Klyuev, V.V.; Leonov, B.I.; Sosnin, F.R.

1986-01-01

304

Approaches to Quality of Control in Diabetes Care  

Microsoft Academic Search

Management methods for quality of diabetes care need new approaches because of the poor metabolic control of most of these patients. Poor quality of care generally results from poor instruction and training rather than from misbehaviour of both patients and their families. Structure quality of care (who and where?), process quality (how?, which are the goals, what resolution is taken

F. Chiarelli; A. Verrotti; L. di Ricco; M. de Martino; G. Morgese

1998-01-01

305

MAP3S/RAINE precipitation chemistry network: quality control  

SciTech Connect

The participants of the precipitation chemistry network of the Multi-State Atmospheric Power Production Pollution Study/Regional Acidity of Industrial Emissions (MAP3S/RAINE) have developed procedures for maintenance of high quality output from the network operation. The documented procedures-most of which were in place before the network began sampling in 1976-include those for site selection and verification, field equipment, laboratory and data handling, and external laboratory quality testing.

Not Available

1980-10-01

306

7 CFR 58.141 - Alternate quality control program.  

Code of Federal Regulations, 2013 CFR

...2013-01-01 2013-01-01 false Alternate quality control program. 58.141 Section...USDA Inspection and Grading Service 1 Quality Specifications for Raw Milk § 58.141 Alternate quality control program. When a plant has...

2013-01-01

307

A comparison of sensory methods in quality control  

Microsoft Academic Search

Many different types of sensorial methods have been proposed and used to evaluate and control the sensory quality of foods. However, not all of them are suitable for incorporation in to quality control programmes. To simplify comparison a distinction is proposed between methods that can be used to define sensory specifications or to select a product quality standard and those

E Costell

2002-01-01

308

QUALITY ASSURANCE AND QUALITY CONTROL IN THE DEVELOPMENT AND APPLICATION OF GROUND-WATER MODELS  

EPA Science Inventory

This report provides background information on quality assurance and defines the role of quality assurance and quality control in grounder modeling. unctional and practical quality-assurance methodology is presented which is written from the perspective of the model user and the ...

309

A control laboratory plant to experiment with hybrid systems  

Microsoft Academic Search

A multivariable test-bed for research and teaching in hybrid system is presented. The process control laboratory plant uses standard industrial components, which introduces more realism and robustness into the experiments with hybrid systems. The paper describes the plant, mathematical modeling of the system and an illustrative experiment. Moreover, criteria for the selection of the hardware\\/software platform for the real-time implementation

A. Gambier; T. Miksch; E. Badreddin

2003-01-01

310

[The Microbiolgy laboratory in nosocomial infection surveillance and control].  

PubMed

The most relevant activities of clinical microbiologist and the laboratory in the surveillance and the control of nosocomial infections (NI) are mainly focused on the collection, analysis and management of the information obtained in the Microbiology Laboratory; the design, development and validation of microbiological techniques, particularly rapid tests for the early detection of nosocomial pathogens, especially those multi-drug resistant ones, and the study of the genetic relationship between them. It also assists in the design of specific programs for the prevention of the NI, and the evaluation of their impact, as well as taking part in educational and training programs on topics related to NI. The management of laboratory resources, and communications with hospital information systems is also important. The most suitable tools for the control of NI include the correct identification at the species level of relevant nosocomial pathogens, analysis of the evolution of resistance to antimicrobials, monitoring sentinel organisms, active surveillance of carriers, and molecular epidemiology studies (genotyping). Prospectively typing of these pathogens, which has been achieved through advances in technology, and dissemination of molecular techniques, have a direct impact on the design of prevention and control interventions. To achieve the maximum performance with all these tools, it is essential to have a good communication strategy and an effective alert system. PMID:23218739

López-Cerero, Lorena; Fernández-Cuenca, Felipe; Pascual, Alvaro

2012-12-06

311

Bacteriological Methods in Water Quality Control Programs. Training Manual.  

ERIC Educational Resources Information Center

|This training manual presents material on basic bacteriological laboratory procedures as required by Federal Register Water Quality Guidelines. Course topics include: characteristics, occurrences, and significance of bacterial indicators of pollution; bacteriological water quality standards and criteria; collection and handling of samples;…

Office of Water Program Operations (EPA), Cincinnati, OH. National Training and Operational Technology Center.

312

Bacteriological Methods in Water Quality Control Programs. Instructor's Guide.  

ERIC Educational Resources Information Center

|This instructor's manual presents material on basic bacteriological laboratory procedures as required by Federal Register Water Quality Guidelines. Course topics include: characteristics, occurrences, and significance of bacterial indicators of pollution; bacteriological water quality standards and criteria; collection and handling of samples;…

Office of Water Program Operations (EPA), Cincinnati, OH. National Training and Operational Technology Center.

313

Participation in Performance-Evaluation Studies by U.S. Geological Survey National Water Quality Laboratory  

USGS Publications Warehouse

Performance-evaluation studies provide customers of the U.S. Geological Survey National Water Quality Laboratory (NWQL) with data needed to evaluate performance and to compare of select laboratories for analytical work. The NWQL participates in national and international performance-evaluation (PE) studies that consist of samples of water, sediment, and aquatic biological materials for the analysis of inorganic constituents, organic compounds, and radionuclides. This Fact Sheet provides a summary of PE study results from January 1993 through April 1997. It should be of particular interest to USGS customers and potential customers of the NWQL, water-quality specialists, cooperators, and agencies of the Federal Government.

Glodt, Stephen R.; Pirkey, Kimberly D.

1998-01-01

314

Quality Assurance and Quality Control Approach for Local and Regional Air Pollutants Emission Inventories in Italy  

Microsoft Academic Search

In the paper the approach followed in Italy for quality assurance (QA) and quality control (QC) in some local and regional emission inventories is presented. Particular attention is devoted to the completeness of data, the quality control of data and the validation of results. The methodology used for emission inventory preparation at local level is at first resumed. Next is

Carlo Trozzi; Rita Vaccaro; Antonella Bernetti; Christian Melis; Monica Pantaleoni

315

7 CFR 58.141 - Alternate quality control program.  

Code of Federal Regulations, 2010 CFR

...2010-01-01 false Alternate quality control program. 58.141 Section...Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing...Inspection and Grading Service 1 Quality Specifications for Raw Milk §...

2010-01-01

316

Regional Planning Model for Water Quality Control.  

National Technical Information Service (NTIS)

The water quality basin planning model presented in this paper is a significant advance over the previous models. The major contributions of this model are the explicit consideration of the water quality measure, temperature and its relationship with the ...

A. B. Whinston D. E. Pingry

1973-01-01

317

Vibration control for precision manufacturing at Sandia National Laboratories  

SciTech Connect

Sandia National Laboratories performs R and D in structural dynamics and vibration suppression for precision applications in weapon systems, space, underwater, transportation and civil structures. Over the last decade these efforts have expanded into the areas of active vibration control and ``smart`` structures and material systems. In addition, Sandia has focused major resources towards technology to support weapon product development and agile manufacturing capability for defense and industrial applications. This paper will briefly describe the structural dynamics modeling and verification process currently in place at Sandia that supports vibration control and some specific applications of these techniques to manufacturing in the areas of lithography, machine tools and flexible robotics.

Hinnerichs, T.; Martinez, D. [Sandia National Labs., Albuquerque, NM (United States). Structural Dynamics and Vibration Control Dept.

1995-04-01

318

[Recommendations on the metrology and the control of the quality of the critical equipments].  

PubMed

Metrology resumes activities which allow the management of results measurement quality. In this paper, we present basic principles of metrology applied to the activities of laboratory medicine. We successively treat general concepts useful for laboratory staff, the interest in the definition of a metrological function and its activities field, the applications in measuring instruments necessary for the exams of medical biology, and the specific documentation control needed. PMID:23765023

Daunizeau, A

2013-06-01

319

10 CFR 26.137 - Quality assurance and quality control.  

Code of Federal Regulations, 2010 CFR

...performance testing samples that have been formulated...challenge the validity screening test around the applicable...by an HHS-certified laboratory. For example, one set of performance testing samples used to challenge a creatinine validity screening test must include...

2010-01-01

320

10 CFR 26.137 - Quality assurance and quality control.  

Code of Federal Regulations, 2010 CFR

...performance testing samples that have been formulated...challenge the validity screening test around the applicable...by an HHS-certified laboratory. For example, one set of performance testing samples used to challenge a creatinine validity screening test must include...

2009-01-01

321

Establishing a quality assurance plan for nucleic acid-based diagnostic laboratories: from planning to implementation  

Microsoft Academic Search

Nucleic acid-based technologies have opened new perspectives in diagnosis, prognosis, and treatment in clinical medicine.\\u000a To maintain patient confidence in this rapidly expanding field and to provide the highest standard of analysis, strict laboratory\\u000a quality assurance procedures must be followed. While impressive break-through are taking place in this field, the need for\\u000a an appropriate and suitable quality assurance (QA) plan

Derliane Oliveira; Sook Fan Yap; Siripan Wongwanich; Baldip Khan; Juan Cristina

2010-01-01

322

Comparison of Laboratory and Field Remote Sensing Methods to Measure Forage Quality  

PubMed Central

Recent research in range ecology has emphasized the importance of forage quality as a key indicator of rangeland condition. However, we lack tools to evaluate forage quality at scales appropriate for management. Using canopy reflectance data to measure forage quality has been conducted at both laboratory and field levels separately, but little work has been conducted to evaluate these methods simultaneously. The objective of this study is to find a reliable way of assessing grassland quality through measuring forage chemistry with reflectance. We studied a mixed grass ecosystem in Grasslands National Park of Canada and surrounding pastures, located in southern Saskatchewan. Spectral reflectance was collected at both in-situ field level and in the laboratory. Vegetation samples were collected at each site, sorted into the green grass portion, and then sent to a chemical company for measuring forage quality variables, including protein, lignin, ash, moisture at 135 °C, Neutral Detergent Fiber (NDF), Acid Detergent Fiber (ADF), Total Digestible, Digestible Energy, Net Energy for Lactation, Net Energy for Maintenance, and Net Energy for Gain. Reflectance data were processed with the first derivative transformation and continuum removal method. Correlation analysis was conducted on spectral and forage quality variables. A regression model was further built to investigate the possibility of using canopy spectral measurements to predict the grassland quality. Results indicated that field level prediction of protein of mixed grass species was possible (r2 = 0.63). However, the relationship between canopy reflectance and the other forage quality variables was not strong.

Guo, Xulin; Wilmshurst, John F.; Li, Zhaoqin

2010-01-01

323

VERSATILE PC-BASED DATA ACQUISITION AND CONTROL SYSTEM: AUTOMATION OF EPA'S AIR TOXICS CONTROL LABORATORY  

EPA Science Inventory

The paper discusses the decision making process which resulted in the selection and configuration of the hardware and software for the Air Toxics Control Laboratory (ATCL) designed and built at EPA's Air and Energy Engineering Research Laboratory, in response to the need for the ...

324

QUALITY ASSURANCE AND QUALITY CONTROL FOR WASTE CONTAINMENT FACILITIES. Project Summary  

EPA Science Inventory

It is generally agreed that both quality assurance (QA) and quality control (QC) are essential to the proper installation and eventual performance of environmentally safe and secure waste containment systems. Even further, there are both manufacturing and construction aspects to...

325

New Approach to Laboratory Motor Control MMCS: The Modular Motor Control System.  

National Technical Information Service (NTIS)

Many projects within the GRASP laboratory involve motion control via electric servo motors, for example robots, hands, camera mounts and tables. To date each project has been based on a unique hardware/software approach. This document discusses the develo...

P. I. Corke

1989-01-01

326

A method for software quality planning, control, and evaluation  

Microsoft Academic Search

Squid is a method and a tool for quality assurance and a control that allows a software development organization to plan and control product quality during development. The Telescience software development project used it to build a remote monitoring and control system based in Antarctica

J. Boegh; Stefano Depanfilis; B. Kitchenham; A. Pasquini

1999-01-01

327

Surface quality control in diamond abrasive finishing  

NASA Astrophysics Data System (ADS)

The paper presents a procedure for measuring laser radiation reflection and scattering coefficients of polished surface. A relation between the scattered light intensity and the polished surface roughness is studied. It is demonstrated that colorimetric characteristics of non-metallic materials can be determined from the light scattering and reflection coefficients. This work has demonstrated a possibility of and created prerequisites for the development of an express method for tentative assessment of polished surface roughness. Of interest is the use of the ?(Rz) function for the purposes of quality inspection of polished surfaces of natural and synthetic stone and other non-metallic materials. It was established that the most relevant parameter of roughness, which can be defined by the light reflection is Rz. The Dependency of the reflection factor from parameter of roughness Rz was approximated by formula with inaccuracy 5-10%. Inaccuracy of the determination of roughness Rz has formed 1%. It was shown that method of the surface roughness control using the light reflection factor is the most efficient for surfaces with roughness Rz <0.3 microns, typical for finish diamond-abrasive machining.

Filatov, Yuriy D.; Sidorko, Volodymyr I.; Filatov, Olexandr Yu.; Yaschuk, Vasil P.; Heisel, Uwe; Storchak, Michael

2009-06-01

328

Electronic Nose for Quality Control of Colombian Coffee Through the Detection of Defects in ``Cup Tests''  

Microsoft Academic Search

This article presents a preliminary study on the analysis of samples of Colombian coffee for the detection and classification of defects (i.e. using ``Cup Tests''), which was conducted in Almacafé quality control laboratory Almacafé in Cúcuta, Colombia). The results obtained show the application of an Electronic Nose (EN), called ``A-NOSE,'' used in the coffee sector for the cupping tests. The

Juan C. Rodríguez; Cristhian M. Duran; Adriana X. Reyes

2009-01-01

329

The making of a successful seminar: Pacific Northwest Laboratory`s {open_quotes}Quest for Quality{close_quotes}  

SciTech Connect

Five contractors located on or near the Hanford Site in southeastern Washington State support technical communications staffs, all trying to meet the needs of one primary customer the U.S. Department of Energy. Historically, these staffs have maintained different processes and standards with regard to document production, and little interaction or information-sharing has occurred. To begin remedying that situation, the communications staff of Pacific Northwest Laboratory, a multiprogram national laboratory located in Richland, Wash., planned and hosted a one-day {open_quotes}Quest for Quality{close_quotes} seminar. The seminar was the first of its kind to comprise technical communications professionals from all the local DOE prime contractors, including technical editors and writers, publications assistants, text processors, and document production staff. The goals of the seminar were to identify ways to improve the quality of Hanford`s communication products and processes, to strengthen ties among technical communications staffs, and to open the lines of communication for future collaborative efforts. An eight-person committee selected topics, arranged facilities, recruited speakers, coordinated activities, hosted the seminar, and prepared proceedings.

Lumetta, C.C.; Downs, S.L.; Parnell, K.A.; Allen, R.E.

1994-10-01

330

Internal-control weaknesses at Department of Energy research laboratories  

SciTech Connect

Two requests were made by Chairman, Permanent Subcommittee on Investigations, Senate Committee on Governmental Affairs, that GAO review the vulnerability of selected Department of Energy (DOE) research facilities to fraud, waste, and abuse. The review examined internal controls over payroll, procurement, and property management at six government-owned, contractor-operated (GOCO) research laboratories (Sandia, Hanford, Argonne, Oak Ridge, Fermi, and Brookhaven) and four government-owned, government-operated energy technology centers (Bartlesville, Laramie, Morgantown, and Pittsburgh). In fiscal 1982, DOE budgeted over $3 billion for its GOCO facilities and over $230 million for its energy technology centers. GAO noted specific problems at a number of the laboratories in each of the areas covered. In many instances, DOE has acknowledged the problems and corrective action is underway or is planned.

Not Available

1982-12-15

331

Los Alamos National Laboratory transuranic waste quality assurance project plan. Revision 1  

SciTech Connect

This Transuranic (TRU) Waste Quality Assurance Project Plan (QAPjP) serves as the quality management plan for the characterization of transuranic waste in preparation for certification and transportation. The Transuranic Waste Characterization/Certification Program (TWCP) consists of personnel who sample and analyze waste, validate and report data; and provide project management, quality assurance, audit and assessment, and records management support, all in accordance with established requirements for disposal of TRU waste at the Waste Isolation Pilot Plant (WIPP) facility. This QAPjP addresses how the TWCP meets the quality requirements of the Carlsbad Area Office (CAO) Quality Assurance Program Description (QAPD) and the technical requirements of the Transuranic Waste Characterization Quality Assurance Program Plan (QAPP). The TWCP characterizes and certifies retrievably stored and newly generated TRU waste using the waste selection, testing, sampling, and analytical techniques and data quality objectives (DQOs) described in the QAPP, the Los Alamos National Laboratory Transuranic Waste Certification Plan (Certification Plan), and the CST Waste Management Facilities Waste Acceptance Criteria and Certification [Los Alamos National Laboratory (LANL) Waste Acceptance Criteria (WAC)]. At the present, the TWCP does not address remote-handled (RH) waste.

NONE

1997-04-14

332

Los Alamos National Laboratory Yucca Mountain Site Characterization Project 1995 quality program status report  

SciTech Connect

This status report summarizes the activities and accomplishments of the Los Alamos National Laboratory Yucca Mountain Site Characterization Project`s (YMP`s) quality assurance program for January 1 to September 30, 1995. The report includes major sections on program activities and trend analysis.

Bolivar, S.L.

1996-07-01

333

Los Alamos National Laboratory Yucca Mountain Site Characterization Project: 1991 quality program status report  

SciTech Connect

This status report summarizes the activities and accomplishments of the Los Alamos National Laboratory (Los Alamos) Yucca Mountain Site Characterization Project`s (YMP) quality assurance program for calendar year 1991. The report is divided into three Sections: Program Activities, Verification Activities, and Trend Analysis.

Not Available

1992-07-01

334

[Implementations of hospital medical equipments quality control system].  

PubMed

Medical equipment quality control is the core content of hospital management. It runs through the whole process of medical equipment management, including the purchase, the installation and acceptance, the use and maintenance, the abandonment. It is the absolute duty for a hospital to assure and control the quality of the equipment. This paper presents the establishment of medical equipment quality control system, as well as a detailed description and analysis in the implementation of this system. Finally, discuss a few experiences in the quality control work. PMID:20812654

Yu, Lu; Liu, Xiaowen; Deng, Houbin; Ge, Yi; Wang, Min

2010-05-01

335

Computer applications in scientific balloon quality control  

Microsoft Academic Search

Seal defects and seal tensile strength are primary determinants of product quality in scientific balloon manufacturing; they therefore require a unit of quality measure. The availability of inexpensive and powerful data-processing tools can serve as the basis of a quality-trends-discerning analysis of products. The results of one such analysis are presently given in graphic form for use on the production

Loren G. Seely; Michael S. Smith

1990-01-01

336

21 CFR 111.105 - What must quality control personnel do?  

Code of Federal Regulations, 2013 CFR

...2013-04-01 2013-04-01 false What must quality control personnel do? 111.105 Section...and Process Control System: Requirements for Quality Control § 111.105 What must quality control personnel do? Quality...

2013-04-01

337

40 CFR 81.80 - Las Vegas Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2010 CFR

...2010-07-01 2010-07-01 false Las Vegas Intrastate Air Quality Control Region. ...Quality Control Regions § 81.80 Las Vegas Intrastate Air Quality Control Region. The Las Vegas Intrastate Air Quality Control...

2010-07-01

338

40 CFR 81.80 - Las Vegas Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2010 CFR

...2009-07-01 2009-07-01 false Las Vegas Intrastate Air Quality Control Region. ...Quality Control Regions § 81.80 Las Vegas Intrastate Air Quality Control Region. The Las Vegas Intrastate Air Quality Control...

2009-07-01

339

40 CFR 81.80 - Las Vegas Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2013 CFR

...2013-07-01 2013-07-01 false Las Vegas Intrastate Air Quality Control Region. ...Quality Control Regions § 81.80 Las Vegas Intrastate Air Quality Control Region. The Las Vegas Intrastate Air Quality Control...

2013-07-01

340

40 CFR 81.77 - Puerto Rico Air Quality Control Region.  

Code of Federal Regulations, 2013 CFR

...2013-07-01 2013-07-01 false Puerto Rico Air Quality Control Region. 81.77 ...Air Quality Control Regions § 81.77 Puerto Rico Air Quality Control Region. The Puerto Rico Air Quality Control Region...

2013-07-01

341

Statistical process control for radiotherapy quality assurance  

Microsoft Academic Search

Every quality assurance process uncovers random and systematic errors. These errors typically consist of many small random errors and a very few number of large errors that dominate the result. Quality assurance practices in radiotherapy do not adequately differentiate between these two sources of error. The ability to separate these types of errors would allow the dominant source(s) of error

Todd Pawlicki; Matthew Whitaker

2005-01-01

342

International Quality Control Is No Easy Task  

ERIC Educational Resources Information Center

In early March, the European Quality Assurance Register for Higher Education was established under what is called the Bologna Process. The 46 countries involved in the process seek to improve the quality and assessment of higher education throughout Europe, thus facilitating students' mobility among institutions and countries and enhancing…

Contreras, Alan

2008-01-01

343

Food and Nutrition Services Quality Control Management Program.  

ERIC Educational Resources Information Center

|A program was conducted to improve the quality of food service through the training of 44 food and nutrition service employees in a 200-bed hospital. A 12-week quality control program was implemented to address four key areas: food temperatures, food accuracy, food quality, and dietary personnel. Learning strategies, emphasizing critical thinking…

Wimsatt-Fraim, Teresa S.

344

Quality-assurance plan and field methods for quality-of-water activities, U.S. Geological Survey, Idaho National Engineering Laboratory, Idaho  

Microsoft Academic Search

Water-quality activities at the Idaho National Engineering Laboratory (INEL) Project Office are part of the US Geological Survey`s (USGS) Water Resources Division (WRD) mission of appraising the quantity and quality of the Nation`s water resources. The purpose of the Quality Assurance Plan (QAP) for water-quality activities performed by the INEL Project Office is to maintain and improve the quality of

Mann

1996-01-01

345

QUALITY CONTROL AND QUALITY ASSURANCE PROCEDURES FOR LEVEL 1 HEALTH EFFECTS BIOASSAYS  

EPA Science Inventory

The report documents the development of a program of quality control (QC) and quality assurance (QA) for the EPA Level 1 environmental assessment health effects bioassays to ensure that all data collected are of known and documented quality sufficient to meet their intended use. ...

346

Quality assurance/quality control procedures for chlorinated hydrocarbons in human breast adipose tissue  

SciTech Connect

Extensive literature exists supporting the accumulation of organochlorine pesticides such as DDT [2,2-bis(p-chlorophenyl)-1,1,1-trichloroethane], and polychlorinated biphenyls (PCBs) in human adipose tissue. Debate has surfaced concerning the link between these environmental contaminants and human breast cancer. Accurate residue analysis and proper analytical procedures are critical in determining the extent to which these compounds play a role in human breast cancer. Further, adequate quality assessment/quality control (QA/QC) is critical for reliable residue analysis. The purpose of this research was twofold: (1) to find an appropriate surrogate for human breast adipose tissue for spiking purposes, as human samples are difficult to obtain, and (2) to develop a human breast adipose tissue pool that yields adequate reproducibility with low coefficients of variation (CVs) for each compound of interest. Using a previously validated method developed in the Analytical Laboratory at Colorado State University, rendered ovine adipose tissue was found to be a suitable spiking material, as it was free of interfering compounds and behaved in a manner similar to human breast adipose tissue throughout the analytical method. Further, this analytical method was used to produce data on three control pool preparations: (A) blended human breast adipose tissue (n = 26), (B) blended and partially rendered human breast adipose tissue (n = 12), and (C) fully blended and rendered human breast adipose tissue (n = 15). The CVs between control pools vary up to 20% for a single compound. The most reproducible preparation procedure requires full blending and rendering. 26 refs., 1 fig., 5 tabs.

Archibeque-Engle, S.; Tessari, J.D.; Winn, D.T. [Colorado State Univ., Fort Collins, CO (United States)

1996-12-27

347

Development of adaptive algorithm for active sound quality control  

Microsoft Academic Search

This paper develops an active sound-quality control (ASQC) system based on the active noise equalization (ANE) technique, and optimizes it with the filtered-error least mean square (FELMS) algorithm and normalized reference signal generator. The ASQC system controls the sound quality of products such as engines by changing the amplitudes of harmonics. This optimized system uses the FELMS algorithm to limit

Sen M. Kuo; Abhijit Gupta; Sridevi Mallu

2007-01-01

348

Artificial Intelligence Approach to Support Statistical Quality Control Teaching  

ERIC Educational Resources Information Center

|Statistical quality control--SQC (consisting of Statistical Process Control, Process Capability Studies, Acceptance Sampling and Design of Experiments) is a very important tool to obtain, maintain and improve the Quality level of goods and services produced by an organization. Despite its importance, and the fact that it is taught in technical…

Reis, Marcelo Menezes; Paladini, Edson Pacheco; Khator, Suresh; Sommer, Willy Arno

2006-01-01

349

Artificial Intelligence Approach to Support Statistical Quality Control Teaching  

ERIC Educational Resources Information Center

Statistical quality control--SQC (consisting of Statistical Process Control, Process Capability Studies, Acceptance Sampling and Design of Experiments) is a very important tool to obtain, maintain and improve the Quality level of goods and services produced by an organization. Despite its importance, and the fact that it is taught in technical and…

Reis, Marcelo Menezes; Paladini, Edson Pacheco; Khator, Suresh; Sommer, Willy Arno

2006-01-01

350

Quantitative assessment of computed radiography quality control parameters  

Microsoft Academic Search

Quality controls for testing the performance of computed radiography (CR) systems have been recommended by manufacturers and medical physicists' organizations. The purpose of this work was to develop a set of image processing tools for quantitative assessment of computed radiography quality control parameters. Automatic image analysis consisted in detecting phantom details, defining regions of interest and acquiring measurements. The tested

O. Rampado; P. Isoardi; R. Ropolo

2006-01-01

351

SCALE - A Quality Control Plan for Nursing Service.  

National Technical Information Service (NTIS)

The implementation of the SCALE (systems for control and analysis of levels of effectiveness) in Michigan for improving the quality of nursing service is detailed. Two primary objectives of the SCALE program for nursing quality control are to provide an o...

1975-01-01

352

Quality control for batch processes using multivariate latent variable methods  

Microsoft Academic Search

The main goal in many processes is to obtain consistent and reproducible operation and end-quality properties. In this thesis the problem of product quality control in batch and semi-batch processes is addressed. Unlike from much of the published literature that uses first principles models, this thesis studies the end-quality feedback control problem using only empirical Partial Least Squares (PLS) models.

Jesus Flores-Cerrillo

2003-01-01

353

Quality Control for Batch Processes Using Multivariate Latent Variable Methods  

Microsoft Academic Search

The main goal in many processes is to obtain consistent and reproducible operation and end-quality properties. In this thesis the problem of product quality control in batch and semi-batch processes is addressed. Unlike from much of the published literature that uses first principles models, this thesis studies the end-quality feedback control problem using only empirical Partial Least Squares (PLS) models.

Jesus Flores-Cerrillo

2003-01-01

354

For and against a European quality control of training.  

PubMed

In a world of medicine that evolves more and more rapidly, sufficient quality of education in the arts and crafts of our discipline and control of this quality are essential for the progress and vitality of Ob/Gyn. There are variations in training within European countries but with the aim of harmonization in training programmes and the flexibility of quality control mechanisms we will meet our objective that is the high standards in the care of woman throughout Europe. PMID:11205701

Dimitrakakis, C; Michalas, S

2001-01-01

355

A Harmonized Quality Control Program for Digital Mammography  

Microsoft Academic Search

Digital mammography is rapidly becoming a mature imaging modality. To maintain high quality in mammography, a routine quality\\u000a control program is necessary to detect drifting or degradation of system performance over time. The American College of Radiology\\u000a is developing a quality control program which will apply to all types of full-field digital mammography equipment, and provide\\u000a effective and more efficient

Martin J. Yaffe; Gordon E. Mawdsley; Aili Bloomquist

2006-01-01

356

40 CFR 81.61 - Evansville (Indiana)-Owensboro-Henderson (Kentucky) Interstate Air Quality Control Region.  

Code of Federal Regulations, 2012 CFR

...Indiana)-Owensboro-Henderson (Kentucky) Interstate Air Quality Control Region...Indiana)-Owensboro-Henderson (Kentucky) Interstate Air Quality Control Region...Indiana)-Owensboro-Henderson (Kentucky) Interstate Air Quality...

2012-07-01

357

Real-time control of a hybrid laboratory plant using a receding horizon control strategy  

Microsoft Academic Search

Real-time results of a receding horizon state-space controller, applied to a laboratory plant with hybrid characteristics, are reported in This work. The control strategy is based on a multi-model scheme and the corresponding switching logic. The control law involves a state-space receding horizon tracking system, a constant-disturbances compensator and a state and constant-disturbances estimator based on an augmented Kalman filter.

Adrian Gambier

2004-01-01

358

Agricultural biological reference materials for analytical quality control  

SciTech Connect

Cooperative work is under way at Agriculture Canada, US Department of Agriculture, and US National Bureau of Standards in an attempt to fill some of the gaps in the world repertoire of reference materials and to provide much needed control materials for laboratories' day to day operations. This undertaking involves the preparation and characterization of a number of agricultural and food materials for data quality control for inorganic constituents. Parameters considered in the development of these materials were material selection based on importance in commerce and analysis; techniques of preparation, processing, and packaging; physical and chemical characterization; homogeneity testing and quantitation (certification). A large number of agricultural/food products have been selected to represent a wide range of not only levels of sought-for constituents (elements) but also a wide range of matrix components such as protein, carbohydrate, dietary fiber, fat, and ash. Elements whose concentrations are being certified cover some two dozen major, minor, and trace elements of nutritional, toxicological, and environmental significance.

Ihnat, M.

1986-01-01

359

Nuclear Technology Series. Course 14: Introduction to Quality Assurance/Quality Control.  

ERIC Educational Resources Information Center

|This technical specialty course is one of thirty-five courses designed for use by two-year postsecondary institutions in five nuclear technician curriculum areas: (1) radiation protection technician, (2) nuclear instrumentation and control technician, (3) nuclear materials processing technician, (4) nuclear quality-assurance/quality-control

Technical Education Research Center, Waco, TX.

360

Nuclear Technology Series. Course 14: Introduction to Quality Assurance/Quality Control.  

ERIC Educational Resources Information Center

This technical specialty course is one of thirty-five courses designed for use by two-year postsecondary institutions in five nuclear technician curriculum areas: (1) radiation protection technician, (2) nuclear instrumentation and control technician, (3) nuclear materials processing technician, (4) nuclear quality-assurance/quality-control

Technical Education Research Center, Waco, TX.

361

Quality control and quality assurance in teacher training institutions: messages from Botswana  

Microsoft Academic Search

The general thesis of this paper is that external factors, such as affiliation to a university, can be used to improve teacher training programmes. The specific issues discussed deal with quality control and assurance. The University of Botswana (UB) is used as a case study. Concepts and terms used are defined, and the key role that quality control and assurance

A. G. Hopkin

1999-01-01

362

The quality management system at the European tritium handling experimental laboratory  

SciTech Connect

The main limitations of conventional Quality Assurance (QA) are discussed with reference to the operational phase of a radio-chemical research laboratory. The paper suggests a broader approach utilizing a Quality Management System (QMS) which focuses on the operational efficiency of a R D organization in terms of reliability, reproducibility, cost effectiveness and safety. The management's role is presented with particular reference to the best fit of managerial style to the organization's mission, culture, personnel and surrounding environment. Qt. QMS policies and QA criteria are suggested for ETHEL to replace conventional QA requirements. Finally, guidelines for designing the ETHEL organizational structure are discussed.

Dizadji, F.; Ferrario, L. (Commission of the European Communities, Inst. for Safety Technology, JRC-Ispra Establishment, I-21020 Ispra (IT))

1992-03-01

363

40 CFR 81.275 - Lake Tahoe Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2013 CFR

... 2013-07-01 2013-07-01 false Lake Tahoe Intrastate Air Quality Control Region...Air Quality Control Regions § 81.275 Lake Tahoe Intrastate Air Quality Control Region. The Lake Tahoe Intrastate Air Quality...

2013-07-01

364

40 CFR 81.273 - Lake County Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2013 CFR

... 2013-07-01 2013-07-01 false Lake County Intrastate Air Quality Control Region...Air Quality Control Regions § 81.273 Lake County Intrastate Air Quality Control Region. The Lake County Intrastate Air Quality...

2013-07-01

365

40 CFR 81.273 - Lake County Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2012 CFR

... 2012-07-01 2012-07-01 false Lake County Intrastate Air Quality Control Region...Air Quality Control Regions § 81.273 Lake County Intrastate Air Quality Control Region. The Lake County Intrastate Air Quality...

2012-07-01

366

40 CFR 81.275 - Lake Tahoe Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2012 CFR

... 2012-07-01 2012-07-01 false Lake Tahoe Intrastate Air Quality Control Region...Air Quality Control Regions § 81.275 Lake Tahoe Intrastate Air Quality Control Region. The Lake Tahoe Intrastate Air Quality...

2012-07-01

367

40 CFR 81.54 - Cook Inlet Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2012 CFR

... 2012-07-01 2012-07-01 false Cook Inlet Intrastate Air Quality Control Region...of Air Quality Control Regions § 81.54 Cook Inlet Intrastate Air Quality Control Region. The Cook Inlet Intrastate Air Quality...

2012-07-01

368

40 CFR 81.32 - Puget Sound Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2013 CFR

...2013-07-01 2013-07-01 false Puget Sound Intrastate Air Quality Control...Quality Control Regions § 81.32 Puget Sound Intrastate Air Quality Control Region. The Puget Sound Intrastate Air Quality...

2013-07-01

369

NIF Projects Controls and Information Systems Software Quality Assurance Plan  

SciTech Connect

Quality achievement for the National Ignition Facility (NIF) and the National Ignition Campaign (NIC) is the responsibility of the NIF Projects line organization as described in the NIF and Photon Science Directorate Quality Assurance Plan (NIF QA Plan). This Software Quality Assurance Plan (SQAP) is subordinate to the NIF QA Plan and establishes quality assurance (QA) activities for the software subsystems within Controls and Information Systems (CIS). This SQAP implements an activity level software quality assurance plan for NIF Projects as required by the LLNL Institutional Software Quality Assurance Program (ISQAP). Planned QA activities help achieve, assess, and maintain appropriate quality of software developed and/or acquired for control systems, shot data systems, laser performance modeling systems, business applications, industrial control and safety systems, and information technology systems. The objective of this SQAP is to ensure that appropriate controls are developed and implemented for management planning, work execution, and quality assessment of the CIS organization's software activities. The CIS line organization places special QA emphasis on rigorous configuration control, change management, testing, and issue tracking to help achieve its quality goals.

Fishler, B

2011-03-18

370

Control de calidad del generador de (sup 113)Sn-(sup 113m)In. (Quality control of the (sup 113)Sn-(sup 113m)In generator).  

National Technical Information Service (NTIS)

Methods for quality control of (sup 113)Sn-(sup 113m)In generators are compared and recommended the most convenient to applicate in hospitals and in more specialized quality control laboratories. The quality of (sup 113)Sn-(sup 113m)In generator produced ...

J. Morin Zorilla E. Olive M. Isaac J. Cruz

1989-01-01

371

Disk Diffusion and MIC Quality Control Ranges for BC-3205 and BC-3781, Two Novel Pleuromutilin Antibiotics  

PubMed Central

MIC and disk diffusion quality control (QC) ranges were established for two new pleuromutilin antimicrobials (BC-3205 and BC-3781) in an eight-laboratory study performed according to Clinical and Laboratory Standards Institute M23-A3 guidelines. Staphylococcus aureus ATCC 29213 and 25923, Streptococcus pneumoniae ATCC 49619, and Haemophilus influenzae ATCC 4927 strains were evaluated. The proposed QC ranges would aid clinical laboratories in testing these compounds following their development for treatment of respiratory and cutaneous infections.

Ross, James E.; Ivezic-Schoenfeld, Zrinka; Paukner, Susanne; Jones, Ronald N.

2012-01-01

372

Internal quality control and external quality assurance in testing for antiphospholipid antibodies: Part II--Lupus anticoagulant.  

PubMed

In addition to the presence of appropriate clinical features, the diagnosis of the antiphospholipid antibody syndrome (APS) fundamentally requires the finding of positive antiphospholipid antibody (aPL) test result(s), with these comprising clot-based assays for the identification of lupus anticoagulant (LA) and immunologic ("solid-phase") assays such as anticardiolipin antibodies (aCL) and anti-?2-glycoprotein I antibodies (a?2GPI). This article is the second of two that review the process for, and provide recommendations to improve, internal quality control (IQC) and external quality assurance (EQA; or proficiency testing) for aPL assays. These processes are critical for ensuring the quality of laboratory test results, and thence the appropriate clinical diagnosis and management of APS. This article covers LA testing. We provide some updated findings from the Royal College of Pathologists of Australasia Haematology Quality Assurance Program, and cover testing results for the past 3 years (2009 to 2011 inclusive). In brief: (1) essentially all laboratories currently perform LA testing using activated partial thromboplastin time (APTT) and dilute Russell viper venom time (dRVVT) methods, and about one-third also employ the kaolin clotting time (KCT); (2) KCT usage has dropped slightly, from around 50% of laboratories in 2009, to around 35% in 2011, presumably reflecting take up of the latest consensus recommendations; (3) other methodologies such as silica clotting time (SCT) and the platelet neutralization procedure (PNP) are only used by <5% of laboratories; (4) interlaboratory coefficients of variation (CVs) are in general moderate, and substantially better than those reported for solid-phase assays such as aCL and a?2GPI, with median (range) values being 11.6% (9.2 to 25.5%) for APTT ratios, 16.7% (10.1 to 19.2%) for KCT ratios, and 11.7% (5.7 to 17.4%) for dRVVT ratios; (5) CVs increase slightly with increasing LA positivity; (6) most laboratories correctly interpreted test findings for LA, reporting normal samples as normal, and LA-positive samples as positive (albeit with varying gradings of positivity); and (7) however, some laboratories found interpretation to be challenging for some samples, namely a weak LA sample (which was reported as normal by around 50% of laboratories) and a very strong LA sample (which was reported as normal by around 10% of laboratories, primarily those that did not perform mixing studies). PMID:22565408

Favaloro, Emmanuel J; Bonar, Roslyn; Marsden, Katherine

2012-05-07

373

The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers  

PubMed Central

Background The cerebrospinal fluid (CSF) biomarkers amyloid ? (A?)-42, total-tau (T-tau), and phosphorylated-tau (P-tau) demonstrate good diagnostic accuracy for Alzheimer’s disease (AD). However, there are large variations in biomarker measurements between studies, and between and within laboratories. The Alzheimer’s Association has initiated a global quality control program to estimate and monitor variability of measurements, quantify batch-to-batch assay variations, and identify sources of variability. In this article, we present the results from the first two rounds of the program. Methods The program is open for laboratories using commercially available kits for A?, T-tau, or P-tau. CSF samples (aliquots of pooled CSF) are sent for analysis several times a year from the Clinical Neurochemistry Laboratory at the Molndal campus of the University of Gothenburg, Sweden. Each round consists of three quality control samples. Results Forty laboratories participated. Twenty-six used INNOTESTenzyme-linked immunosorbent assay kits, 14 used Luminex xMAP with the INNO-BIA AlzBio3 kit (both measure A?-(1-42), P-tau(181P), and T-tau), and 5 used Meso Scale Discovery with the A? triplex (A?N-42, A?N-40, and A?N-38) or T-tau kits. The total coefficients of variation between the laboratories were 13% to 36%. Five laboratories analyzed the samples six times on different occasions. Within-laboratory precisions differed considerably between biomarkers within individual laboratories. Conclusions Measurements of CSF AD biomarkers show large between-laboratory variability, likely caused by factors related to analytical procedures and the analytical kits. Standardization of laboratory procedures and efforts by kit vendors to increase kit performance might lower variability, and will likely increase the usefulness of CSF AD biomarkers.

Mattsson, Niklas; Andreasson, Ulf; Persson, Staffan; Arai, Hiroyuki; Batish, Sat Dev; Bernardini, Sergio; Bocchio-Chiavetto, Luisella; Blankenstein, Marinus A.; Carrillo, Maria C.; Chalbot, Sonia; Coart, Els; Chiasserini, Davide; Cutler, Neal; Dahlfors, Gunilla; Duller, Stefan; Fagan, Anne M.; Forlenza, Orestes; Frisoni, Giovanni B.; Galasko, Douglas; Galimberti, Daniela; Hampel, Harald; Handberg, Aase; Heneka, Michael T.; Herskovits, Adrianna Z.; Herukka, Sanna-Kaisa; Holtzman, David M.; Humpel, Christian; Hyman, Bradley T.; Iqbal, Khalid; Jucker, Mathias; Kaeser, Stephan A.; Kaiser, Elmar; Kapaki, Elisabeth; Kidd, Daniel; Klivenyi, Peter; Knudsen, Cindy S.; Kummer, Markus P.; Lui, James; Llado, Albert; Lewczuk, Piotr; Li, Qiao-Xin; Martins, Ralph; Masters, Colin; McAuliffe, John; Mercken, Marc; Moghekar, Abhay; Molinuevo, Jose Luis; Montine, Thomas J.; Nowatzke, William; O'Brien, Richard; Otto, Markus; Paraskevas, George P.; Parnetti, Lucilla; Petersen, Ronald C.; Prvulovic, David; de Reus, Herman P. M.; Rissman, Robert A.; Scarpini, Elio; Stefani, Alessandro; Soininen, Hilkka; Schroder, Johannes; Shaw, Leslie M.; Skinningsrud, Anders; Skrogstad, Brith; Spreer, Annette; Talib, Leda; Teunissen, Charlotte; Trojanowski, John Q.; Tumani, Hayrettin; Umek, Robert M.; Van Broeck, Bianca; Vanderstichele, Hugo; Vecsei, Laszlo; Verbeek, Marcel M.; Windisch, Manfred; Zhang, Jing; Zetterberg, Henrik; Blennow, Kaj

2013-01-01

374

QCTVA: quality-controlled temporal video adaptation  

NASA Astrophysics Data System (ADS)

Multimedia streaming is becoming more and more popular. Seamless video streaming in heterogeneous networks like the Internet turns out as almost impossible due to varying network conditions -- streams must be adapted to the current network QoS. Temporal scalability is one of the most reasonable adaptation techniques because it is fast and easy to perform. Today's approaches simply drop frames out of a video without spending much effort on finding an intelligent dropping behavior. This usually leads to good adaptation results in terms of bandwidth consumption but also to suboptimal video quality within the given bounds. Our approach offers analysis of video streams to achieve the qualitatively best temporal scalability. For this reason, we introduce a data structure called modification lattice which represents all frame dropping combinations within a sequence of frames. On the basis of the modification lattice, quality estimations on frame sequences can be performed. Moreover, a heuristic for fast and efficient quality computation in a modification lattice is presented. Experimental results illustrate that temporal video adaptation based on QCTVA information leads to a better video quality compared to "usual" frame dropping approaches. Furthermore, QCTVA offers frame priority lists for videos. Based on these priorities, numerous adaptation techniques can increase their overall performance when using QCTVA.

Leopold, Klaus; Hellwagner, Hermann; Kropfberger, Michael

2003-11-01

375

Kierratyspolttoaineiden Iaadunvalvonta (Quality Control of Recycled Fuels).  

National Technical Information Service (NTIS)

Solid recycled fuels (SRF) are used in existing multifuel heat and power plants in Finland as complementary fuels in co-combustion, when fuel qualities have to be suitable for such plants. Impurities and in homogeneousness are examples of special characte...

S. Ajanko A. Moilanen J. Juvonen

2005-01-01

376

Urban Water Runoff and Water Quality Control.  

National Technical Information Service (NTIS)

The 1972 Amendments to FWPCA specifically require that non-point sources of water pollution be considered in the development of water quality management plans for both local and areawide planning. Urban runoff often accounts for a major portion of the non...

J. T. Wildrick K. Kuhn W. R. Kerns

1976-01-01

377

Radiative transfer theory verified by controlled laboratory experiments.  

PubMed

We report the results of high-accuracy controlled laboratory measurements of the Stokes reflection matrix for suspensions of submicrometer-sized latex particles in water and compare them with the results of a numerically exact computer solution of the vector radiative transfer equation (VRTE). The quantitative performance of the VRTE is monitored by increasing the volume packing density of the latex particles from 2% to 10%. Our results indicate that the VRTE can be applied safely to random particulate media with packing densities up to ?2%. VRTE results for packing densities of the order of 5% should be taken with caution, whereas the polarized bidirectional reflectivity of suspensions with larger packing densities cannot be accurately predicted. We demonstrate that a simple modification of the phase matrix entering the VRTE based on the so-called static structure factor can be a promising remedy that deserves further examination. PMID:24104804

Mishchenko, Michael I; Goldstein, Dennis H; Chowdhary, Jacek; Lompado, Arthur

2013-09-15

378

Assuring Quality Control of Clinical Education in Multiple Clinical Affiliates.  

ERIC Educational Resources Information Center

|A plan was developed to assure equivalency of clinical education among the medical laboratory technician (MLT) programs affiliated with Sandhills Community College. The plan was designed by faculty to monitor the quality of clinical courses offered by the clinical affiliates. The major strategies were to develop competencies, slide/tape modules,…

Davis, Judith A.

379

Proactive product quality control: An integrated product and process control approach to MIMO systems  

Microsoft Academic Search

Real-time control of product performance parameters is a key for proactive quality control (QC), as it can prevent the occurrence of potential quality problems in the earliest stage of manufacturing. It is recognized that dynamic product QC must be coordinated with the control of the process through which the product is manufactured. The integrated product and process control (IPPC) design

Zheng Liu; Jie Xiao; Yinlun Huang

2009-01-01

380

Hanford Environmental Information System (HEIS). Volume 9, Field Quality Control subject area  

SciTech Connect

The purpose of the HEIS Field Quality Control subject area is to manage the data acquired from field quality control samples. Field quality control samples are used to determine if sample contamination has occurred at some point in the sampling process. Four major types of data comprise the Field Quality Control subject area. Data about samples, spike samples, chemical and/or radiologic analysis of field quality control samples, and relationships between field quality control and non-quality control samples.

Schreck, R.I. [Westinghouse Hanford Co., Richland, WA (United States)

1994-04-15

381

Product quality control in reduced dimension spaces  

Microsoft Academic Search

In the first part of the thesis, control of the full molecular weight distribution (MWD) in a semi-batch polymerization reactor is considered. A new batch-to-batch optimization methodology for producing a desired MWD using an approximate fundamental model is presented. The optimization approach is also extended for use as an on-line control method by incorporating a multivariable statistical process control (MSPC)

Tracy Lee Clarke-Pringle

2000-01-01

382

Product Quality Control in Reduced Dimension Spaces  

Microsoft Academic Search

In the first part of the thesis, control of the full molecular weight distribution (MWD) in a semi-batch polymerization reactor is considered. A new batch-to-batch optimization methodology for producing a desired MWD using an approximate fundamental model is presented. The optimization approach is also extended for use as an on-line control method by incorporating a multivariable statistical process control (MSPC)

Tracy Lee Clarke-Pringle

1999-01-01

383

HAZWRAP (Hazardous Waste Remedial Actions Program) requirements for quality control of analytical data. [HAZWRAP  

SciTech Connect

This paper describes the quality control (QC) requirements for analysis, and data reporting in support of the HAZWRAP Support Contract Office. These requirements are to be used for site investigation and remedial investigation work in support of remediation work for the Department of Defense. The QC requirements are based on the Environmental Protection Agency protocols. The sampling requirements include specified frequencies for trip, field, and rinsate blanks and field duplicates. The sampling program also includes review of the work plans, sampling procedures, and audits of sample collection. The analytical requirements include a laboratory approval process which encompasses performance samples, review of laboratory quality assurance plans, reviews of site specific work plans, and laboratory audits. The QC program includes three levels. 1 fig., 3 tabs.

Miller, M.S.; Zolyniak, J.W.

1988-01-01

384

40 CFR 81.270 - Northern Arizona Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2012 CFR

...2012-07-01 2012-07-01 false Northern Arizona Intrastate Air Quality Control Region...Control Regions § 81.270 Northern Arizona Intrastate Air Quality Control Region. The Northern Arizona Intrastate Air Quality Control...

2012-07-01

385

40 CFR 81.271 - Central Arizona Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2012 CFR

...2012-07-01 2012-07-01 false Central Arizona Intrastate Air Quality Control Region...Control Regions § 81.271 Central Arizona Intrastate Air Quality Control Region. The Central Arizona Intrastate Air Quality Control...

2012-07-01

386

40 CFR 81.272 - Southeast Arizona Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2012 CFR

...2012-07-01 2012-07-01 false Southeast Arizona Intrastate Air Quality Control Region...Control Regions § 81.272 Southeast Arizona Intrastate Air Quality Control Region. The Southeast Arizona Intrastate Air Quality Control...

2012-07-01

387

21 CFR 111.130 - What quality control operations are required for returned dietary supplements?  

Code of Federal Regulations, 2012 CFR

... 2013-04-01 false What quality control operations are required...OPERATIONS FOR DIETARY SUPPLEMENTS Production and Process Control System: Requirements for Quality Control § 111.130 What quality control operations are...

2013-04-01

388

21 CFR 111.127 - What quality control operations are required for packaging and labeling operations?  

Code of Federal Regulations, 2012 CFR

... 2013-04-01 false What quality control operations are required...OPERATIONS FOR DIETARY SUPPLEMENTS Production and Process Control System: Requirements for Quality Control § 111.127 What quality control operations are...

2013-04-01

389

21 CFR 111.65 - What are the requirements for quality control operations?  

Code of Federal Regulations, 2012 CFR

...What are the requirements for quality control operations? 111...Requirement to Establish a Production and Process Control System...are the requirements for quality control operations? You must implement quality control operations in...

2013-04-01

390

40 CFR 81.32 - Puget Sound Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2010 CFR

...2009-07-01 false Puget Sound Intrastate Air Quality Control Region. 81.32 Section...Control Regions § 81.32 Puget Sound Intrastate Air Quality Control Region. The Puget Sound Intrastate Air Quality Control Region...

2009-07-01

391

40 CFR 81.32 - Puget Sound Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2010 CFR

...2010-07-01 false Puget Sound Intrastate Air Quality Control Region. 81.32 Section...Control Regions § 81.32 Puget Sound Intrastate Air Quality Control Region. The Puget Sound Intrastate Air Quality Control Region...

2010-07-01

392

21 CFR 111.135 - What quality control operations are required for product complaints?  

Code of Federal Regulations, 2013 CFR

...2013-04-01 2013-04-01 false What quality control operations are required for product complaints...and Process Control System: Requirements for Quality Control § 111.135 What quality control operations are required for product...

2013-04-01

393

40 CFR 81.97 - Southwest Florida Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2012 CFR

...2012-07-01 2012-07-01 false Southwest Florida Intrastate Air Quality Control Region...Control Regions § 81.97 Southwest Florida Intrastate Air Quality Control Region. The Southwest Florida Intrastate Air Quality Control...

2012-07-01

394

40 CFR 81.202 - Northwest Ohio Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2013 CFR

...2013-07-01 2013-07-01 false Northwest Ohio Intrastate Air Quality Control Region...Control Regions § 81.202 Northwest Ohio Intrastate Air Quality Control Region. The Northwest Ohio Intrastate Air Quality Control...

2013-07-01

395

40 CFR 81.162 - Northeast Plateau Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2012 CFR

...2012-07-01 2012-07-01 false Northeast Plateau Intrastate Air Quality Control Region...Control Regions § 81.162 Northeast Plateau Intrastate Air Quality Control Region. The Northeast Plateau Intrastate Air Quality Control...

2012-07-01

396

40 CFR 81.248 - Southeastern Alaska Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2012 CFR

... 2012-07-01 false Southeastern Alaska Intrastate Air Quality Control Region...Control Regions § 81.248 Southeastern Alaska Intrastate Air Quality Control Region. The Southeastern Alaska Intrastate Air Quality Control...

2012-07-01

397

40 CFR 81.178 - Southern Delaware Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2013 CFR

...2013-07-01 2013-07-01 false Southern Delaware Intrastate Air Quality Control Region...Control Regions § 81.178 Southern Delaware Intrastate Air Quality Control Region. The Southern Delaware Intrastate Air Quality Control...

2013-07-01

398

Continuous Phase Analysis: A Step Forward for Quality Control  

Microsoft Academic Search

In recent years there has been a steady increase in the use of continuous analysis for the control of cement production. This analysis has mainly been directed towards measurement and control of the chemistry of the raw materials. Control of the chemistry is necessary in cement production, but this does not guarantee the quality of the final product. Further downstream

Duane Crutchfield; Fred Blackham; Peter Storer; Ian Madsen

399

Power factor controller-an integrated power quality device  

Microsoft Academic Search

This paper describes a new integrated power quality device-power factor controller (PFC) for power distribution system and industrial power circuit applications. A PFC integrates breaker-switched capacitor banks into a compact design with low cost sensing elements and an intelligent control unit. The device provides more accurate voltage control and power factor correction than traditional shunt capacitor bank installations. The integrated

R. Tinggren; Yi Hu; Le Tang; H. Mathews; R. Tyner

1999-01-01

400

International external quality assurance for laboratory identification and typing of Streptococcus agalactiae (Group B streptococci).  

PubMed

We report the results from the first international multicenter external quality assessment (EQA) studies for molecular and serological typing of group B streptococcus (GBS) strains as part of DEVANI (Design of a Vaccine against Neonatal Infections), a pan-European program. A questionnaire-based surveillance was undertaken among eight laboratories participating in DEVANI and six laboratories not participating in DEVANI from 13 countries in order to assess their current microbiological procedures for GBS screening, diagnosis, and typing. GBS strains from three EQA distributions were characterized using molecular and serological methods based on GBS capsular polysaccharide typing. Participants were asked to test the first distribution using their current serotyping and genotyping methods. The Strep-B-Latex agglutination method was the most widely used method, with a typeability value of >90%. A multiplex PCR assay for GBS capsular gene typing was also used by 2 of 14 centers, which achieved a typeability value of 93%; this assay detected only 9 of 10 GBS capsular polysaccharide genes. From the second and third EQA studies, standardized protocols were prepared for serological and molecular typing of GBS strains based on the Strep-B-Latex agglutination method and a novel multiplex PCR assay that detected all 10 GBS capsular types (Ia to IX). These standardized protocols are being used by many European laboratories, and as the use of these methods increases, it is imperative to continuously improve and assess laboratory performance and offer training to any laboratories that have technical difficulties. PMID:21325542

Afshar, Baharak; Broughton, Karen; Creti, Roberta; Decheva, Antoaneta; Hufnagel, Markus; Kriz, Paula; Lambertsen, Lotte; Lovgren, Marguerite; Melin, Pierrette; Orefici, Graziella; Poyart, Claire; Radtke, Andreas; Rodriguez-Granger, Javier; Sørensen, Uffe B Skov; Telford, John; Valinsky, Lea; Zachariadou, Levantia; Efstratiou, Androulla

2011-02-16

401

International External Quality Assurance for Laboratory Identification and Typing of Streptococcus agalactiae (Group B Streptococci)?  

PubMed Central

We report the results from the first international multicenter external quality assessment (EQA) studies for molecular and serological typing of group B streptococcus (GBS) strains as part of DEVANI (Design of a Vaccine against Neonatal Infections), a pan-European program. A questionnaire-based surveillance was undertaken among eight laboratories participating in DEVANI and six laboratories not participating in DEVANI from 13 countries in order to assess their current microbiological procedures for GBS screening, diagnosis, and typing. GBS strains from three EQA distributions were characterized using molecular and serological methods based on GBS capsular polysaccharide typing. Participants were asked to test the first distribution using their current serotyping and genotyping methods. The Strep-B-Latex agglutination method was the most widely used method, with a typeability value of >90%. A multiplex PCR assay for GBS capsular gene typing was also used by 2 of 14 centers, which achieved a typeability value of 93%; this assay detected only 9 of 10 GBS capsular polysaccharide genes. From the second and third EQA studies, standardized protocols were prepared for serological and molecular typing of GBS strains based on the Strep-B-Latex agglutination method and a novel multiplex PCR assay that detected all 10 GBS capsular types (Ia to IX). These standardized protocols are being used by many European laboratories, and as the use of these methods increases, it is imperative to continuously improve and assess laboratory performance and offer training to any laboratories that have technical difficulties.

Afshar, Baharak; Broughton, Karen; Creti, Roberta; Decheva, Antoaneta; Hufnagel, Markus; Kriz, Paula; Lambertsen, Lotte; Lovgren, Marguerite; Melin, Pierrette; Orefici, Graziella; Poyart, Claire; Radtke, Andreas; Rodriguez-Granger, Javier; S?rensen, Uffe B. Skov; Telford, John; Valinsky, Lea; Zachariadou, Levantia; Efstratiou, Androulla

2011-01-01

402

Radiation control program at the Donald W. Douglas Laboratories  

Microsoft Academic Search

From third Health Physics Society midyear topical symposium; Los ; Angeles, California, USA (29 Jan 1969). See CONF-690103P1. The McDonnell ; Douglas Astronautics Company built and operates the Donald W. Douglas ; Laboratories at Richland, Washington. The 57,600 ft² facility is located ; on a 112 acre site. One wing of this multipurpose laboratory houses a ; radioisotope laboratory and

M. L. Smith; C. A. Willis

1972-01-01

403

115. QUALITY CONTROL BOARD FOR MAINTENANCE AND INSPECTION AT SOUTH ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

115. QUALITY CONTROL BOARD FOR MAINTENANCE AND INSPECTION AT SOUTH SIDE OF MECHANICAL AND ELECTRICAL ROOM (110), LSB (BLDG. 770), FACING WEST ON EXTERIOR WALL OF QUALITY ASSURANCE ROOM (106A) - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 West, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

404

Quality control of ocean temperature and salinity profile data  

Microsoft Academic Search

The objective of data quality control (QC) is to ensure consistency within a single data set or throughout a historical database. This is a vital step to be taken with any data set before scientific analysis can be proceed. A redesign of data quality procedures for temperature and salinity profile data undertaken by the Naval Oceanographic Office (NAVOCEANO) during the

Kenneth P. Grembowicz; Betty S. Howell

2002-01-01

405

Autonomy vs. Control: Quality Assurance and Governmental Policy in Flanders  

Microsoft Academic Search

Higher education in Flanders has seen some major changes in the 1990s. One of the key elements of the new higher education regulations was the quality assessment system. This exemplified best the government's policy of granting all institutions of higher education autonomy, making them responsible for their policies, while still keeping the quality of higher education somewhat under governmental control.

Kurt De Wit; Jef C. Verhoeven

406

Online quality control with Raman spectroscopy in pharmaceutical tablet manufacturing  

Microsoft Academic Search

Quality testing for tablet composition and uniformity at the manufacturing stage is critical to the pharmaceutical industry. However, current off-line, destructive, wet chemistry analysis incurs significant costs and long test times. This paper introduces a methodology to form a population batch size for quality control sampling in tablet manufacturing for an alternative online testing technology, Raman spectroscopy. An approach is

Julie Ann Stuart Williams; Winston Bonawi-Tan

2004-01-01

407

Implementing a Laboratory Information Management System (LIMS) in an Army Corps of Engineers' Water Quality Testing Laboratory  

Microsoft Academic Search

Today's environmental laboratory faces numerous challenge such as enhanced regulatory oversight, decreasing costs per tests, and numerous laboratory accreditations that are offered and\\/or required. Selecting the LIMS that will “fit” your laboratory is important, but so is finding a system that has the flexibility to conform to the changes that will be required by the laboratory over the years. These

Elizabeth Turner; Christine Paszko; Don Kolva

2001-01-01

408

Achieving indoor air quality through contaminant control  

SciTech Connect

Federal laws outlining industry`s responsibilities in creating a healthy, hazard-free workspace are well known. OSHA`s laws on interior air pollution establish threshold limit values (TLVs) and permissible exposure limits (PELs) for more than 500 potentially hazardous substances found in manufacturing operations. Until now, OSHA has promulgated regulations only for the manufacturing environment. However, its recently-proposed indoor air quality (IAQ) ruling, if implemented, will apply to all workspaces. It regulates IAQ, including environmental tobacco smoke, and requires employers to write and implement IAQ compliance plans.

Katzel, J.

1995-07-10

409

Quality control methodology and implementation of X-radiation standards beams, mammography level, following the standard IEC 61267.  

PubMed

This study presents the results of the establishment of a quality control program developed and applied for the X-ray system of the Calibration Laboratory of IPEN. The X-ray standard beams, mammography level, using molybdenum and aluminum as additional filtration were established after the application of this quality control and the spectrometry of these qualities was made. The reference ionization chamber has traceability to the PTB. The radiation qualities RQR-M, RQA-M, RQN-M and RQB-M, following the recommendations of the IEC 61267 and the IAEA TRS 457 were established. PMID:22364787

Corrêa, E L; Vivolo, V; Potiens, M P A

2012-02-15

410

Control of Water Quality in Transmission and Distribution Mains  

Microsoft Academic Search

Far from improving with age, the quality of water deteriorates, as evidenced by changes in appearance as well as in odor and taste. However, the technology exists to control this deterioration, if effectively applied.

Hugo T. Victoreen

1974-01-01

411

21 CFR 211.22 - Responsibilities of quality control unit.  

Code of Federal Regulations, 2013 CFR

...DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR FINISHED PHARMACEUTICALS Organization and Personnel § 211.22 Responsibilities of quality control unit. (a) There...

2013-04-01

412

Intercell Currents in Assembly of Modules: Quality Control Considerations.  

National Technical Information Service (NTIS)

Quality control considerations in battery fabrication with regard to intercell currents in an assembly of modules of thin cell, bipolar plate design connected in parallel electrically and in series hydraulically, are examined. The effects on battery perfo...

C. J. Gabriel P. A. Mosier-Boss S. Szpak J. J. Smith

1991-01-01

413

Metropolitan Dallas Ft. Worth Intrastate Air Quality Control Region.  

National Technical Information Service (NTIS)

The status is presented of the Federally owned facilities within the Metropolitan Dallas - Ft. Worth, Texas Air Quality Control Region with regard to the implementation of the objectives prescribed by the Clean Air Act, as amended. Fuel usage, refuse disp...

F. M. Orr

1971-01-01

414

ACCURUN 803 Nucleic Acid Negative Quality Control (HIV ...  

Center for Biologics Evaluation and Research (CBER)

... Approved Products. Substantially Equivalent 510(k ... Nucleic Acid Negative Quality Control (HIV, HCV ... Product: ACCURUN 803 Nucleic Acid Negative ... More results from www.fda.gov/biologicsbloodvaccines/bloodbloodproducts/approvedproducts

415

VERIFICATION TESTING OF AIR POLLUTION CONTROL TECHNOLOGY QUALITY MANAGEMENT PLAN  

EPA Science Inventory

This document is the basis for quality assurance for the Air Pollution Control Technology Verification Center (APCT Center) operated under the U.S. Environmental Protection Agency (EPA). It describes the policies, organizational structure, responsibilities, procedures, and qualit...

416

30 CFR 28.31 - Quality control plans; contents.  

Code of Federal Regulations, 2010 CFR

...FOR USE WITH DIRECT CURRENT IN PROVIDING SHORT-CIRCUIT PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control ...and assembly work conducted in the applicant's plant...Box 371954, Pittsburgh, PA 15250-7954;...

2009-07-01

417

30 CFR 28.31 - Quality control plans; contents.  

Code of Federal Regulations, 2010 CFR

...FOR USE WITH DIRECT CURRENT IN PROVIDING SHORT-CIRCUIT PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control ...and assembly work conducted in the applicant's plant...Box 371954, Pittsburgh, PA 15250-7954;...

2010-07-01

418

30 CFR 28.31 - Quality control plans; contents.  

Code of Federal Regulations, 2013 CFR

...FOR USE WITH DIRECT CURRENT IN PROVIDING SHORT-CIRCUIT PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control ...and assembly work conducted in the applicant's plant...Box 371954, Pittsburgh, PA 15250-7954;...

2013-07-01

419

Requirements for quality control of analytical data for the Environmental Restoration Program  

SciTech Connect

The Environmental Restoration (ER) Program was established for the investigation and remediation of inactive US Department of Energy (DOE) sites and facilities that have been declared surplus in terms of their previous uses. The purpose of this document is to Specify ER requirements for quality control (QC) of analytical data. Activities throughout all phases of the investigation may affect the quality of the final data product, thus are subject to control specifications. Laboratory control is emphasized in this document, and field concerns will be addressed in a companion document Energy Systems, in its role of technical coordinator and at the request of DOE-OR, extends the application of these requirements to all participants in ER activities. Because every instance and concern may not be addressed in this document, participants are encouraged to discuss any questions with the ER Quality Assurance (QA) Office, the Analytical Environmental Support Group (AESG), or the Analytical Project Office (APO).

Engels, J.

1992-12-01

420

Indoor air quality: Sources and control  

NASA Astrophysics Data System (ADS)

The nature and origin of major classes of indoor pollutants is discussed. Measures to control such pollutants are also discussed. Attention is focused on what perhaps is the major indoor pollutant in the developed countries radon and its progeny. (AIP)

Sextro, Richard G.; Nero, Anthony V.; Grimsrud, David T.

1985-11-01

421

Austempered ductile iron—process control and quality assurance  

Microsoft Academic Search

Recent interest in the development of austempered ductile cast irons has resulted in considerable study of the physical metallurgy\\u000a and mechanical properties of these high strength, high toughness cast irons. Equally important is the identification of process\\u000a control and quality assurance factors to achieve the desired properties successfully and consistently. In this study, aspects\\u000a of austempered ductile iron quality control

R. C. Voigt; C. R. Loper

1984-01-01

422

Risk-Reliability Programming for Optimal Water Quality Control  

Microsoft Academic Search

A risk-reliability programming approach is developed for optimal allocation of releases for control of water quality downstream of a multipurpose reservoir. Additionally, the approach allows the evaluation of optimal risk\\/reliability values. Risk is defined as a probability of not satisfying constraints given in probabilistic form, e.g., encroachment of water quality reservation on that for flood control. The objective function includes

Slobodan P. Simonovic; Gerald T. Orlob

1984-01-01

423

Protein N -glycosylation, protein folding, and protein quality control  

Microsoft Academic Search

Quality control of protein folding represents a fundamental cellular activity. Early steps of protein N-glycosylation involving the removal of three glucose and some specific mannose residues in the endoplasmic reticulum have\\u000a been recognized as being of importance for protein quality control. Specific oligosaccharide structures resulting from the\\u000a oligosaccharide processing may represent a glycocode promoting productive protein folding, whereas others may

Jürgen Roth; Christian Zuber; Sujin Park; Insook Jang; Yangsin Lee; Katarina Gaplovska Kysela; Valérie Le Fourn; Roger Santimaria; Bruno Guhl; Jin Won Cho

2010-01-01

424

Quality control and assurance applied to the analysis of environmental samples collected from known geothermal sites. Final report  

Microsoft Academic Search

The components of an analytical quality control and assurance program for the analysis of trace toxic and priority pollutants are reviewed in general. It is recommended that these principles be applied to develop increased confidence in a laboratory's analytical accuracy by establishing validated standard operating procedures with built in controls and internal cross checks and developing an approved standard operating

1978-01-01

425

Quality Assurance and Quality Control Practices For Rehabilitation of Sewer and Water Mains  

EPA Science Inventory

As part of the US Environmental Protection Agency (EPA)?s Aging Water Infrastructure Research Program, several areas of research are being pursued including a review of quality assurance and quality control (QA/QC) practices and acceptance testing during the installation of rehab...

426

HANDBOOK: QUALITY ASSURANCE/QUALITY CONTROL (QA/QC) PROCEDURES FOR HAZARDOUS WASTE INCINERATION  

EPA Science Inventory

Resource Conservation and Recovery Act regulations for hazardous waste incineration require trial burns by permit applicants. uality Assurance Project Plan (QAPjP) must accompany a trial burn plan with appropriate quality assurance/quality control procedures. uidance on the prepa...

427

Quality Assurance and Quality Control Practices for Rehabilitation of Sewer and Water Mains  

EPA Science Inventory

As part of the US Environmental Protection Agency (EPA)â??s Aging Water Infrastructure Research Program, several areas of research are being pursued, including a review of quality assurance and quality control (QA/QC) practices and acceptance testing during the installation of reha...

428

Development and Testing of a Nuclear Quality Assurance/Quality Control Technician Curriculum. Final Report.  

ERIC Educational Resources Information Center

|A project was conducted to field test selected first- and second-year courses in a postsecondary nuclear quality assurance/quality control (QA/QC) technician curriculum and to develop the teaching/learning modules for seven technical specialty courses remaining in the QA/QC technician curriculum. The field testing phase of the project involved…

Espy, John; And Others

429

Development and Testing of a Nuclear Quality Assurance/Quality Control Technician Curriculum. Final Report.  

ERIC Educational Resources Information Center

A project was conducted to field test selected first- and second-year courses in a postsecondary nuclear quality assurance/quality control (QA/QC) technician curriculum and to develop the teaching/learning modules for seven technical specialty courses remaining in the QA/QC technician curriculum. The field testing phase of the project involved the…

Espy, John; And Others

430

Groundwater plume control with phytotechnologies at Argonne National Laboratory.  

SciTech Connect

In 1999, Argonne National Laboratory-East (ANL-E) designed and installed a series of engineered plantings consisting of a vegetative cover system and approximately 800 hybrid poplars and willows rooting at various predetermined depths. The plants were installed using various methods including Applied Natural Science's TreeWell{reg_sign} system. The goal of the installation was to protect downgradient surface and groundwater by hydraulic control of the contaminated plume. This goal was to be accomplished by intercepting the contaminated groundwater with the tree roots, removing moisture from the upgradient soil area, reducing water infiltration, preventing soil erosion, degrading and/or transpiring the residual VOCs, and removing tritium from the subsoil and groundwater. The U.S. EPA Superfund Innovative Technology Evaluation Program (SITE) and ANL-E evaluated the demonstration. The effectiveness of the various plantings was monitored directly through groundwater measurements and samples, and indirectly via soil moisture probes, plant tissue analysis, microbial studies, geochemical analysis, and sap flow monitoring. A weather station with data logging equipment was installed. ANL-E modeled the predicted effect of the plants on the groundwater using MODFLOW. The demonstration has lasted three growing seasons and continues. This paper presents the results of the sampling, monitoring, and modeling efforts to date. The project was not only successful in reducing the groundwater contaminant flow and the contaminants at the source; it also provides insight into the techniques that are useful for measuring and predicting the effectiveness of future similar projects.

Rock, S.; Negri, M. C.; Quinn, J.; Wozniak, J.,; McPherson, J.

2002-07-16

431

Microcomputer-controlled laboratory system for field potential experiments.  

PubMed

A microcomputer-controlled laboratory system for hippocampal field potential experiments was constituted. This system realized the quasi-simultaneous processing of execution of stimulation, data acquisition, data display and data analysis by means of a microcomputer for the first time. To attain this quasi-simultaneous processing, a new algorithm for drawing a tangent on the wave-form of the potential was contrived, which enabled rapid analysis of an arbitrary population spike even in the case of generation of double spikes. The system has the following functions: (1) execution of the programmed stimulation paradigm, (2) analog/digital (A/D) conversion of the evoked field potential with a sampling interval of more than 50 microseconds per channel, (3) display of the A/D converted wave-form data on a CRT and storage of the data on a floppy disk, (4) on-line analysis of the population excitatory postsynaptic potential (EPSP) and population spike, (5) more detailed off-line analysis of the field potentials, and (6) output of the wave-form data and measured values through a printer and an X-Y plotter. PMID:2770334

Ashida, H; Maru, E; Tatsuno, J

1989-08-01

432

Air quality and pollution control in Taiwan  

NASA Astrophysics Data System (ADS)

Due to limited land and great emphasis on economic growth in the past, Taiwan has an extremely heavy environmental burden. Population density, factory density, as well as densities of motor vehicles are several times higher than those in the United States and Japan. According to the statistics of 1991, the Pollutant Standards Index (PSI) fell mostly in the "moderate" category, i.e., in the range of 50-100. There were 16.25% of the monitored days with PSI above 100, and 0.51% with PSI beyond 200. Suspended particulates were the major pollutant responsible for PSI above 100, followed by carbon monoxide, ozone, and sulfur dioxide. The measures adopted to control air pollution can be divided into four categories, namely law and regulations, control measures on stationary sources, mobile sources and construction projects. The latest amended Air Pollution Control Act was promulgated on 1 February 1992. Several major revisions were introduced to make the amended Act much more stringent than the 1982 amendment, especially on the offenses likely to endanger public health and welfare. In regard to stationary sources, a permit system was enacted to regulate the establishment and alteration of stationary sources. Designated stationary sources are required to be equipped with automatic monitoring facilities. An inspection and enforcement program have expanded to cover more than 10,000 factories. Major control measures for motor vehicles include introducing stringent emission standards for gasoline-fueled vehicles and diesel cars, setting up ratification and approval program for new vehicle model, promoting the inspection/maintenance program on in-used motorcycles and encouraging the use of unleaded and low sulfur fuels. In order to control the pollution caused by construction work, constructors are required to use low-pollution machinery and engineering methods and incorporate pollution prevention into the construction budget.

Fang, Shu-Hwei; Chen, Hsiung-Wen

433

Electronic Nose for Quality Control of Colombian Coffee Through the Detection of Defects in “Cup Tests”  

Microsoft Academic Search

This article presents a preliminary study on the analysis of samples of Colombian coffee for the detection and classification of defects (i.e. using “Cup Tests”), which was conducted in Almacafe´ quality control laboratory Almacafe´ in Cu´cuta, Colombia). The results obtained show the application of an Electronic Nose (EN), called “A-NOSE,” used in the coffee sector for the cupping tests. The

Juan C. Rodri´guez; Cristhian M. Duran; Adriana X. Reyes

2009-01-01

434

Software quality assurance and software safety in the Biomed Control System  

SciTech Connect

The Biomed Control System is a hardware/software system used for the delivery, measurement and monitoring of heavy-ion beams in the patient treatment and biology experiment rooms in the Bevalac at the Lawrence Berkeley Laboratory (LBL). This paper describes some aspects of this system including historical background philosophy, configuration management, hardware features that facilitate software testing, software testing procedures, the release of new software quality assurance, safety and operator monitoring. 3 refs.

Singh, R.P.; Chu, W.T.; Ludewigt, B.A.; Marks, K.M.; Nyman, M.A.; Renner, T.R.; Stradtner, R.

1989-10-31

435

Command & Control in Virtual Environments: Laboratory Experimentation to Compare Virtual with Physical.  

National Technical Information Service (NTIS)

Research in command and control is advancing rapidly through a campaign of laboratory experimentation using the ELICIT (Experimental Laboratory for counterterrorism intelligence game Investigating Collaboration Information-sharing, and Trust) multiplayer ...

A. A. Adams B. J. Hudgens J. G. Lee J. R. Andraus R. D. Bergin

2010-01-01

436

78 FR 12101 - Importer of Controlled Substances; Notice of Application; Caraco Pharmaceutical Laboratories, LTD.  

Federal Register 2010, 2011, 2012, 2013

...of Controlled Substances; Notice of Application; Caraco Pharmaceutical Laboratories, LTD. Pursuant to Title 21 Code of Federal...a), this is notice that on November 22, 2012, Caraco Pharmaceutical Laboratories, Ltd., 270 Prospect Plains Road,...

2013-02-21

437

Automatic control and data acquisition system for combustion laboratory applications. Master's thesis  

SciTech Connect

A modern computer based automatic data acquisition/control system was installed at the Department of Aeronautics' Combustion Laboratory. This system utilizes an HP-85 desktop computer as system controller for the HP-3054A data acquisition system. Large quantities of high quality data can be acquired at high data rates and stored for future use or processed real time in closed loop feedback control circuis for precise process control and display. Other electromechanical equipment such as Visicorders provide analog real time data and run in parallel with digital equipment but can be remotely controlled for precise timing of experiments. Interactive programs on the HP-85 computer allow the experimenter to do preliminary calculations, initial experiment set-up, and to perform accurate process control of system functions. On line data reduction and display of results is performed by the system CRT display, the 7225B Plotter, or the system printer. Four basic experiments/experimental apparatuses are currently automated using the automatic data acquisition system; a light scattering experiment, a vitiated air heater, a solid fuel ramjet, and a turbojet combustor test rig. The first three applications are discussed in subsequent sections along with the measurement techniques used to implement the process.

Hansen, B.J.

1982-10-01

438

Quality Assurance Guidelines for Testing Using Rapid HIV Antibody Tests Waived Under the Clinical Laboratory Improvement Amendments of 1988.  

National Technical Information Service (NTIS)

This document provides guidance on quality assurance (QA) practices for sites using or planning to use rapid test kits to detect antibodies to the human immunodeficiency virus (HIV) waived under the Clinical Laboratory Improvement Amendments of 1988 (CLIA...

2007-01-01

439

Research Group Introduction : Mechanical Control Engineering Laboratory, Mechanical Engineering Department, Shibaura Institute of Technology  

NASA Astrophysics Data System (ADS)

Mechanical Control Engineering Laboratory focuses on the control theory and implementation for the robotic applications. The research themes include network based tele-operation, mobile robots control for network relay, autonomous outdoor mobile robot and biped robot.

??, ?

440

FRAUD, CORRUPTION IN THE PRIVATE SECTOR AND INTERNAL CONTROL QUALITY  

Microsoft Academic Search

The global economic crunch had a big impact on the private sector all over the world. Media and controllers presented cases of corruption in business and identified special areas where companies, governments, investors, consumers and stakeholders can contribute to stop fraud and corruption. Controllers and auditors are rebuilding public trust in the accounting profession, in order to provide high-quality training,

Lumini?a IONESCU

2011-01-01

441

Statistical Process Control: Going to the Limit for Quality.  

ERIC Educational Resources Information Center

|Defines the concept of statistical process control, a quality control method used especially in manufacturing. Generally, concept users set specific standard levels that must be met. Makes the point that although employees work directly with the method, management is responsible for its success within the plant. (CH)|

Training, 1987

1987-01-01

442

Quality control of plasma facing components for Tore Supra  

Microsoft Academic Search

The high technology components used in fusion devices, especially high heat flux (HHF) plasma facing components, require high reliability. This can be only guaranteed by a very high level of quality control (QC) through rigorous acceptance inspection procedure. Qualification of the power exhaust capabilities of HHF components in normal operation requires control of their thermal and mechanical integrity. During the

Alain Durocher; J Schlosser; J. J Cordier; G Agarici

2003-01-01

443

Assessing Quality of Evolved Agent Controllers for Collective Gathering  

Microsoft Academic Search

The research goal was to engineer an agent collective that most effectively accomplished a cooperative gathering task. The proper setting of agent controller parameters was vital for the finding of agent behavior that most effectively gathered a high quantity and quality of resources in an unknown virtual environment. We tested the efficacy of evolutionary design of agent controller parameters, via

A. E. Eiben; G. S. Nitschke; M. C. Schut

2005-01-01

444

Agent-based bee product quality control system  

Microsoft Academic Search

A lot of problems exist in bee product quality control, management and traceability such as the considerable influence of human factors, weakness of handling emergencies and lack of support on intelligent key technologies. This study explores the application of agent theory, method and technique to solve the problems of process control, traceability, intelligent information watching and information technology application to

Zhu Yeping; Li Shijuan; Liu Shengping; E. Yue; Zhao Jing

2010-01-01

445

42 CFR 84.42 - Proposed quality control plans; approval by the Institute.  

Code of Federal Regulations, 2011 CFR

... 2011-10-01 false Proposed quality control plans; approval by the Institute. 84.42...APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Quality Control § 84.42 Proposed quality control plans; approval by the Institute....

2011-10-01

446

42 CFR 431.810 - Basic elements of the Medicaid eligibility quality control (MEQC) program.  

Code of Federal Regulations, 2012 CFR

...Basic elements of the Medicaid eligibility quality control (MEQC) program. 431.810 Section 431...ORGANIZATION AND GENERAL ADMINISTRATION Quality Control Medicaid Eligibility Quality Control (meqc) Program § 431.810 Basic...

2012-10-01

447

42 CFR 84.42 - Proposed quality control plans; approval by the Institute.  

Code of Federal Regulations, 2012 CFR

... 2012-10-01 false Proposed quality control plans; approval by the Institute. 84.42...APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Quality Control § 84.42 Proposed quality control plans; approval by the Institute....

2012-10-01

448

20 CFR 602.41 - Proper expenditure of Quality Control granted funds.  

Code of Federal Regulations, 2012 CFR

...false Proper expenditure of Quality Control granted funds. 602.41 Section...ADMINISTRATION, DEPARTMENT OF LABOR QUALITY CONTROL IN THE FEDERAL-STATE UNEMPLOYMENT INSURANCE SYSTEM Quality Control Grants to States § 602.41...

2012-04-01

449

20 CFR 602.42 - Effect of failure to implement Quality Control program.  

Code of Federal Regulations, 2012 CFR

...Effect of failure to implement Quality Control program. 602.42 Section 602...ADMINISTRATION, DEPARTMENT OF LABOR QUALITY CONTROL IN THE FEDERAL-STATE UNEMPLOYMENT INSURANCE SYSTEM Quality Control Grants to States § 602.42...

2012-04-01

450

40 CFR 81.156 - Southern Maryland Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2012 CFR

...2012-07-01 2012-07-01 false Southern Maryland Intrastate Air Quality Control Region...Control Regions § 81.156 Southern Maryland Intrastate Air Quality Control Region. The Southern Maryland Intrastate Air Quality...

2012-07-01

451

40 CFR 81.155 - Central Maryland Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2012 CFR

...2012-07-01 2012-07-01 false Central Maryland Intrastate Air Quality Control Region...Control Regions § 81.155 Central Maryland Intrastate Air Quality Control Region. The Central Maryland Intrastate Air Quality...

2012-07-01

452

40 CFR 81.260 - South Central Iowa Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2013 CFR

...2013-07-01 2013-07-01 false South Central Iowa Intrastate Air Quality Control...Quality Control Regions § 81.260 South Central Iowa Intrastate Air Quality Control Region. The South Central Iowa Intrastate Air...

2013-07-01

453

40 CFR 81.253 - South Central Kansas Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2013 CFR

...2013-07-01 2013-07-01 false South Central Kansas Intrastate Air Quality Control...Quality Control Regions § 81.253 South Central Kansas Intrastate Air Quality Control Region. The South Central Kansas Intrastate Air...

2013-07-01

454

40 CFR 81.166 - South Central Coast Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2013 CFR

...2013-07-01 2013-07-01 false South Central Coast Intrastate Air Quality Control...Quality Control Regions § 81.166 South Central Coast Intrastate Air Quality Control Region. The South Central Coast Intrastate Air...

2013-07-01

455

40 CFR 81.17 - Metropolitan Los Angeles Air Quality Control Region.  

Code of Federal Regulations, 2010 CFR

...2010-07-01 false Metropolitan Los Angeles Air Quality Control Region. 81.17...Regions § 81.17 Metropolitan Los Angeles Air Quality Control Region. The Metropolitan Los Angeles Air Quality Control Region...

2010-07-01

456

40 CFR 81.17 - Metropolitan Los Angeles Air Quality Control Region.  

Code of Federal Regulations, 2010 CFR

...2009-07-01 false Metropolitan Los Angeles Air Quality Control Region. 81.17...Regions § 81.17 Metropolitan Los Angeles Air Quality Control Region. The Metropolitan Los Angeles Air Quality Control Region...

2009-07-01

457

30 CFR 28.32 - Proposed quality control plans; approval by MSHA.  

Code of Federal Regulations, 2013 CFR

...2013-07-01 2013-07-01 false Proposed quality control plans; approval by MSHA. 28.32...PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.32 Proposed quality control plans; approval by MSHA. (a)...

2013-07-01

458

21 CFR 866.2480 - Quality control kit for culture media.  

Code of Federal Regulations, 2013 CFR

...false Quality control kit for culture media. 866.2480 Section 866.2480 Food...2480 Quality control kit for culture media. (a) Identification. A quality control kit for culture media is a device that consists of...

2013-04-01

459

40 CFR 81.201 - Mansfield-Marion Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2010 CFR

...2009-07-01 2009-07-01 false Mansfield-Marion Intrastate Air Quality Control...Quality Control Regions § 81.201 Mansfield-Marion Intrastate Air Quality Control Region. The Mansfield-Marion Intrastate Air...

2009-07-01

460

40 CFR 81.201 - Mansfield-Marion Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2010 CFR

...2010-07-01 2010-07-01 false Mansfield-Marion Intrastate Air Quality Control...Quality Control Regions § 81.201 Mansfield-Marion Intrastate Air Quality Control Region. The Mansfield-Marion Intrastate Air...

2010-07-01

461

40 CFR 81.163 - Sacramento Valley Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2010 CFR

...2009-07-01 2009-07-01 false Sacramento Valley Intrastate Air Quality Control...Quality Control Regions § 81.163 Sacramento Valley Intrastate Air Quality Control Region. The Sacramento Valley Intrastate Air...

2009-07-01

462

40 CFR 81.163 - Sacramento Valley Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2010 CFR

...2010-07-01 2010-07-01 false Sacramento Valley Intrastate Air Quality Control...Quality Control Regions § 81.163 Sacramento Valley Intrastate Air Quality Control Region. The Sacramento Valley Intrastate Air...

2010-07-01

463

40 CFR 81.104 - Central Pennsylvania Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2013 CFR

... 2013-07-01 false Central Pennsylvania Intrastate Air Quality Control Region...Control Regions § 81.104 Central Pennsylvania Intrastate Air Quality Control Region. The Central Pennsylvania Intrastate Air Quality...

2013-07-01

464

40 CFR 81.23 - Southwest Pennsylvania Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2013 CFR

...2013-07-01 false Southwest Pennsylvania Intrastate Air Quality Control Region...Control Regions § 81.23 Southwest Pennsylvania Intrastate Air Quality Control Region. The Southwest Pennsylvania Intrastate Air Quality...

2013-07-01

465

40 CFR 81.14 - Metropolitan Chicago Interstate Air Quality Control Region.  

Code of Federal Regulations, 2012 CFR

... 2012-07-01 false Metropolitan Chicago Interstate Air Quality Control Region...Control Regions § 81.14 Metropolitan Chicago Interstate Air Quality Control Region. The Metropolitan Chicago Interstate Air Quality...

2012-07-01

466

40 CFR 81.152 - Southern Coastal Plain Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2012 CFR

...2012-07-01 false Southern Coastal Plain Intrastate Air Quality Control Region...Regions § 81.152 Southern Coastal Plain Intrastate Air Quality Control Region. The Southern Coastal Plain Intrastate Air Quality Control...

2012-07-01

467

40 CFR 81.128 - Genesee-Finger Lakes Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2013 CFR

...2013-07-01 false Genesee-Finger Lakes Intrastate Air Quality Control Region...Regions § 81.128 Genesee-Finger Lakes Intrastate Air Quality Control Region. The Genesee-Finger Lakes Intrastate Air Quality Control...

2013-07-01

468

40 CFR 81.128 - Genesee-Finger Lakes Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2012 CFR

...2012-07-01 false Genesee-Finger Lakes Intrastate Air Quality Control Region...Regions § 81.128 Genesee-Finger Lakes Intrastate Air Quality Control Region. The Genesee-Finger Lakes Intrastate Air Quality Control...

2012-07-01

469

21 CFR 866.5910 - Quality control material for cystic fibrosis nucleic acid assays.  

Code of Federal Regulations, 2010 CFR

... Quality control material for cystic fibrosis nucleic acid assays. 866... Quality control material for cystic fibrosis nucleic acid assays. (a...Quality control material for cystic fibrosis nucleic acid assays. A...

2010-04-01

470

21 CFR 866.5910 - Quality control material for cystic fibrosis nucleic acid assays.  

Code of Federal Regulations, 2010 CFR

... Quality control material for cystic fibrosis nucleic acid assays. 866... Quality control material for cystic fibrosis nucleic acid assays. (a...Quality control material for cystic fibrosis nucleic acid assays. A...

2009-04-01

471

21 CFR 866.5910 - Quality control material for cystic fibrosis nucleic acid assays.  

Code of Federal Regulations, 2013 CFR

... Quality control material for cystic fibrosis nucleic acid assays. 866... Quality control material for cystic fibrosis nucleic acid assays. (a...Quality control material for cystic fibrosis nucleic acid assays. A...

2013-04-01

472

40 CFR 81.153 - Western Mountain Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2012 CFR

...2012-07-01 2012-07-01 false Western Mountain Intrastate Air Quality Control Region...Control Regions § 81.153 Western Mountain Intrastate Air Quality Control Region. The Western Mountain Intrastate Air Quality...

2012-07-01

473

40 CFR 81.147 - Eastern Mountain Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2012 CFR

...2012-07-01 2012-07-01 false Eastern Mountain Intrastate Air Quality Control Region...Control Regions § 81.147 Eastern Mountain Intrastate Air Quality Control Region. The Eastern Mountain Intrastate Air Quality...

2012-07-01

474

40 CFR 81.117 - Southeast Missouri Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2012 CFR

... 2012-07-01 false Southeast Missouri Intrastate Air Quality Control Region...Control Regions § 81.117 Southeast Missouri Intrastate Air Quality Control Region. The Southeast Missouri Intrastate Air Quality...

2012-07-01

475

Research review: Indoor air quality control techniques  

SciTech Connect

Techniques for controlling the concentration of radon, formaldehyde, and combustion products in the indoor air are reviewed. The most effective techniques, which are generally based on limiting or reducing indoor pollutant source strengths, can decrease indoor pollutant concentrations by a factor of 3 to 10. Unless the initial ventilation rate is unusually low, it is difficult to reduce indoor pollutant concentrations more than approximately 50% by increasing the ventilation rate of an entire building. However, the efficiency of indoor pollutant control by ventilation can be enhanced through the use of local exhaust ventilation near concentrated sources of pollutants, by minimizing short circuiting of air from supply to exhaust when pollutant sources are dispersed and, in some situations, by promoting a displacement flow of air and pollutants toward the exhaust. Active air cleaning is also examined briefly. Filtration and electrostatic air cleaning for removal of particles from the indoor air are the most practical and effective currently available techniques of air cleaning. 49 refs., 7 figs.

Fisk, W.J.

1986-10-01

476

The World Health Organization's External Quality Assurance System Proficiency Testing Program Has Improved the Accuracy of Antimicrobial Susceptibility Testing and Reporting among Participating Laboratories Using NCCLS Methods  

PubMed Central

A total of 150 laboratories in 33 countries that followed the NCCLS testing procedures participated in the World Health Organization's External Quality Assurance System for Antimicrobial Susceptibility Testing (EQAS-AST) from January 1998 through March 2001. Laboratories tested seven bacterial isolates for antimicrobial resistance and reported the results to the Centers for Disease Control and Prevention (CDC) in Atlanta, Ga. The results were compared to the results generated at the CDC with the NCCLS broth microdilution and disk diffusion reference methods. Although there were few testing errors with Salmonella enterica subsp. enterica serovar Enteritidis, drugs that are not appropriate for therapy of Salmonella infections were tested and reported by 136 (91%) of 150 laboratories. In addition, 29 (20%) of 150 laboratories used the Staphylococcus aureus breakpoints to report oxacillin results for Staphylococcus saprophyticus. For a vanB-containing Enterococcus faecalis strain, 124 (83%) of 150 laboratories correctly reported vancomycin results that were ±1 doubling dilution from the reference MIC or ±3 mm from the reference disk diffusion result. Of the laboratories that tested Streptococcus agalactiae by disk diffusion, 17% reported nonsusceptible results for penicillin in error. While 110 laboratories (73%) tested the S. pneumoniae challenge isolate against a fluoroquinolone, 83% tested it against ciprofloxacin, for which there are no NCCLS interpretive criteria. Ten of 12 laboratories testing levofloxacin and 4 of 4 laboratories testing ofloxacin by an MIC method correctly reported resistant results for the isolate. Feedback letters sent to participating laboratories highlighted areas of susceptibility testing in individual laboratories that needed improvement. The positive impact of the feedback letters and the overall effectiveness of the EQAS program were documented in repeat testing challenges with pneumococci and staphylococci. The 31 and 19% increases in the numbers of laboratories using appropriate testing methods for pneumococci and staphylococci, respectively, in 2000 versus 1998 indicate that laboratory performance is improving.

Chaitram, Jasmine M.; Jevitt, Laura A.; Lary, Sara; Tenover, Fred C.

2003-01-01

477

Spot identification and quality control in cell-based microarrays  

PubMed Central

Cell-based microarrays are being increasingly used as a tool for combinatorial and high throughput screening of cellular microenvironments. Analysis of microarrays requires several steps, including microarray imaging, identification of cell spots, quality control, and data exploration. While high content image analysis, cell counting, and cell pattern recognition methods are established, there is a need for new post-processing and quality control methods for cell-based microarrays used to investigate combinatorial microenvironments. Previously, microarrayed cell spot identification and quality control were performed manually, leading to excessive processing time and potentially resulting in human bias. This work introduces an automated approach to identify cell-based microarray spots and spot quality control. The approach was used to analyze the adhesion of murine cardiac side population cells on combinatorial arrays of extracellular matrix proteins. Microarrays were imaged by automated fluorescence microscopy and cells were identified using open-source image analysis software (CellProfiler™). From these images, clusters of cells making up single cell spots were reliably identified by analyzing the distances between cells using a density-based clustering algorithm (OPTICS). Naïve Bayesian classifiers trained on manually scored training sets identified good and poor quality spots using spot size, number of cells per spot, and cell location as quality control criteria. Combined, the approach identified 78% of high quality spots and 87% of poor quality spots. Full factorial analysis of the resulting microarray data revealed that collagen IV exhibited the highest positive effect on cell attachment. This data processing approach allows for fast and unbiased analysis of cell-based microarray data.

Bauer, Michael; Kim, Keekyoung; Qiu, Yiling; Calpe, Blaise; Khademhosseini, Ali; Liao, Ronglih; Wheeldon, Ian

2012-01-01

478

Performance of dust allergen carpet samplers in controlled laboratory studies.  

PubMed

Allergens and other pollutants in house dust are collected using a variety of dust samplers that are assumed to operate similarly. This factorial design study compared sampler performance under controlled environmental conditions. House dust with known particle sizes (212-90, 90-45, and <45??m) and allergen concentrations were sampled from new carpet squares with varying denier, pile height and pile densities. Dust mass and allergen recovery for total dust mites (Der p 1 and Der f 1), cat (Fel d 1) and cockroach allergen (Bla g 1) were assessed using the Eureka Mighty Mite (EURK), the High Volume Small Surface Sampler (HVS), or the American Industrial Hygiene Association (AIHA) method. Allergen concentrations were quantified using enzyme-linked immunosorbent assays, and dust mass results were corrected for carpet fiber shedding. Samplers were compared by exploring mass collection efficiency (CE=fiber corrected dust mass/applied dust mass) and concentration ratio (CR=allergen concentration in collected sample/allergen concentration in test dust). Test dust allergen concentrations varied by particle size fraction due to varying laboratory performance over time. The EURK and HVS samplers had CEs of 41-63% in the small and medium particle size fractions, and collected less than 20% of the available dust from the large size fraction. The AIHA CE ranged from 10% to 17% in the medium and small particle size fractions, but collected little dust in the largest particle size fraction. The AIHA and HVS samplers were more likely to acquire more representative and less variable allergen CRs compared with the EURK method. Health studies that use allergen concentration as an exposure metric need to consider the implications of sampler performance when interpreting links to health outcomes and development of health-based standards for allergens in house dust. PMID:23281430

Adgate, John L; Banerjee, Sudipto; Wang, Mei; McKenzie, Lisa M; Hwang, Jooyeon; Ja Cho, Sook; Ramachandran, Gurumurthy

2013-01-02

479

Clinical pharmacology quality assurance program: models for longitudinal analysis of antiretroviral proficiency testing for international laboratories.  

PubMed

: Among National Institutes of Health HIV Research Networks conducting multicenter trials, samples from protocols that span several years are analyzed at multiple clinical pharmacology laboratories (CPLs) for multiple antiretrovirals. Drug assay data are, in turn, entered into study-specific data sets that are used for pharmacokinetic analyses, merged to conduct cross-protocol pharmacokinetic analysis, and integrated with pharmacogenomics research to investigate pharmacokinetic-pharmacogenetic associations. The CPLs participate in a semiannual proficiency testing (PT) program implemented by the Clinical Pharmacology Quality Assurance program. Using results from multiple PT rounds, longitudinal analyses of recovery are reflective of accuracy and precision within/across laboratories. The objectives of this longitudinal analysis of PT across multiple CPLs were to develop and test statistical models that longitudinally: (1) assess the precision and accuracy of concentrations reported by individual CPLs and (2) determine factors associated with round-specific and long-term assay accuracy, precision, and bias using a new regression model. A measure of absolute recovery is explored as a simultaneous measure of accuracy and precision. Overall, the analysis outcomes assured 97% accuracy (±20% of the final target concentration of all (21) drug concentration results reported for clinical trial samples by multiple CPLs). Using the Clinical Laboratory Improvement Act acceptance of meeting criteria for ?2/3 consecutive rounds, all 10 laboratories that participated in 3 or more rounds per analyte maintained Clinical Laboratory Improvement Act proficiency. Significant associations were present between magnitude of error and CPL (Kruskal-Wallis P < 0.001) and antiretroviral (Kruskal-Wallis P < 0.001). PMID:24052065

Difrancesco, Robin; Rosenkranz, Susan L; Taylor, Charlene R; Pande, Poonam G; Siminski, Suzanne M; Jenny, Richard W; Morse, Gene D

2013-10-01

480

Annual Technol Conference Transactions - American Society for Quality Control, 34th: Quality in the New Decade, 1980  

SciTech Connect

The conference transactions contain 129 papers dealing with such QC topics as: computer aided QC; metrology; human factors, risk, and product liability law; QC in food processing; statistical technique; quality costs principle; food, drug, and cosmetics; energy; automotive; metals; quality cost and startegic planning; quality motivation; textile and needle trades; environmental quality assurance; biomedical; service industry quality costs; application of quality circles; electronics; advanced reliability techniques; management; aerospace and defense planning and systems; small business quality control inspection; and reliability applications.

Not Available

1980-05-01

481

Effect of Pre-Analytical Errors on Quality of Laboratory Medicine at a Neuropsychiatry Institute in North India  

Microsoft Academic Search

Advances in instrument technology and automation have simplified tasks in laboratory diagnostics reducing errors during analysis\\u000a thereby improving the quality of test results. However studies show that most laboratory errors occur in the pre-analytical\\u000a phase. In view of the paucity of studies examining pre-analytical errors, we examined a total of 1513 request forms received\\u000a at our laboratory during a 3 month

Neelam Chhillar; Sarbjeet Khurana; Rachna Agarwal; Neeraj Kumar Singh

2011-01-01

482

Run-to-run product quality control of batch processes  

Microsoft Academic Search

Batch processes have been increasingly used in the production of low volume and high value added products. Consequently, optimization\\u000a control in batch processes is crucial in order to derive the maximum benefit. In this paper, a run-to-run product quality\\u000a control based on iterative learning optimization control is developed. Moreover, a rigorous theorem is proposed and proven\\u000a in this paper, which

Li Jia; Ji-ping Shi; Da-shuai Cheng; Min-sen Chiu

2009-01-01

483

Related party transactions, benefits of control and earnings quality  

Microsoft Academic Search

Controlling shareholders pursue benefits of control (private benefits and shared benefits) via related party transactions,\\u000a which result in different levels of earnings quality. Using data from all A-share listed companies in Shenzhen and Shanghai\\u000a stock markets in the year 2001 and 2002, we found that when the share ratio of controlling shareholder is less than 50%, they\\u000a prefer pursuing private

Yan Tong; Huacheng Wang

2008-01-01

484