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1

Analytical laboratory quality control charting  

SciTech Connect

In life the importance of setting goals is stressed. The desired end result must be envisioned to chart a path and determine indicators to provide feedback on the process. Quality does not happen by accident but is achieved through a constant process of setting goals, process development, monitoring process indicators, fine tuning the process, and achieving results. These goals are to be focused and clearly measurable. In industry and life the setting of goals with clear process indicators is often difficult because of the variable end result and scarcity of measurements. Laboratories are fortunate in that they have a plethora of measurements with known or desired end results (controls) to monitor the process and give instantaneous feedback on quality. A key quality tool used by the laboratory to monitor and evaluate the lab processes is control charting. When properly utilized Quality Control (QC) Charts allow labs to be proactive in addressing problems rather than reactive. Several methods are available for control charting and some are listed in the references/information sources. The content for this paper is based on the control-charting program utilized at the Department of Energy's Fernald site. This control-charting program has specific areas of emphasis, simple charts, trend analyses, and effective follow-up.

O'Bryan, Ervin F.

2001-06-11

2

[Quality control in the physician's laboratory].  

PubMed

All measures in quality assurance, including quality control, aim at minimizing and detecting errors in the clinical laboratory. Quality control is performed by using internal quality control material and by participating in external quality assessment schemes. These measures for quality assurance are an essential part of the new index of clinical tests, issued by the federal department for internal affairs on 1 January 1994. An agreement has been signed by the representatives of the associations performing laboratory analyses (hospitals, physicians, private laboratories) and by the health insurances, saying that internal as well as external quality control will be mandatory in Switzerland beginning 1 July 1995. The FMH is now asked to supply the health insurances with a list of physicians performing laboratory analyses until 1 July. For physicians who will not have registered neither with the respective professional organization nor one of the health care insurances by July 1995, the reimbursements will be reduced. PMID:7770815

Hänseler, E

1995-05-01

3

Analytical Laboratory Quality Control Charting.  

National Technical Information Service (NTIS)

In life the importance of setting goals is stressed. The desired end result must be envisioned to chart a path and determine indicators to provide feedback on the process. Quality does not happen by accident but is achieved through a constant process of s...

E. F. O'Bryan

2001-01-01

4

Analytical laboratory quality control charting  

Microsoft Academic Search

In life the importance of setting goals is stressed. The desired end result must be envisioned to chart a path and determine indicators to provide feedback on the process. Quality does not happen by accident but is achieved through a constant process of setting goals, process development, monitoring process indicators, fine tuning the process, and achieving results. These goals are

OBryan; Ervin F

2001-01-01

5

Laboratory Quality Control Based on Risk Management  

PubMed Central

Risk management is the systematic application of management policies, procedures, and practices to the tasks of analyzing, evaluating, controlling and monitoring risk (the effect of uncertainty on objectives). Clinical laboratories conduct a number of activities that could be considered risk management including verification of performance of new tests, troubleshooting instrument problems and responding to physician complaints. Development of a quality control plan for a laboratory test requires a process map of the testing process with consideration for weak steps in the preanalytic, analytic and postanalytic phases of testing where there is an increased probability of errors. Control processes that either prevent or improve the detection of errors can be implemented at these weak points in the testing process to enhance the overall quality of the test result. This manuscript is based on a presentation at the 2nd International Symposium on Point of Care Testing held at King Faisal Specialist Hospital in Riyadh, Saudi Arabia on October 12-13, 2010. Risk management principles will be reviewed and progress towards adopting a new Clinical and Laboratory Standards Institute Guideline for developing laboratory quality control plans based on risk management will be discussed.

Nichols, James H.

2011-01-01

6

How to Write a Laboratory Quality Control Manual (597).  

National Technical Information Service (NTIS)

This course will provide detailed instructions and practice in how to develop and write a laboratory quality control manual. Upon completion of the course, each participant will be able to identify the desirable elements of a laboratory quality control pr...

1978-01-01

7

Quality assurance and quality control in the laboratory andrology  

PubMed Central

Quality assurance (QA) and quality control (QC) are fundamental aspects of any laboratory measurement. However, in comparison with other medical disciplines, the need for QA and QC in laboratory andrology has been recognized only recently. Furthermore, there is evidence that the effort required to undertake QA and QC has not been wholly welcomed by some clinicians. Nevertheless, accrediting bodies and regulatory authorities increasingly require evidence that laboratories have effective QA and QC measures in place because both are central to the quality management processes. Following the publication of the 5th edition of the World Health Organization Laboratory Manual, existing QA and QC systems will need to be updated to take into account some of the methodological changes recommended by the manual. Three of these are discussed in this commentary; they relate to: (i) the move to infer semen volume from its weight; (ii) the re-classification of sperm motility grades from four to three; and (iii) the publication of a lower reference limit for morphology of 4% (with a corresponding 95% confidence interval of 3%–4%). The importance of QA and QC in all laboratory tests, including up and coming new tests to assess sperm DNA integrity, is discussed. The need for adequate initial training and continuing professional development programmes to support laboratory scientists performing andrology is also described.

Pacey, Allan A.

2010-01-01

8

Quality control samples for routine use in water laboratories  

Microsoft Academic Search

Quality management systems in water laboratories have steadily improved during the past years, and the use of quality control samples is becoming routine. A selection of quality control samples has been designed and prepared by the Danish reference laboratory for water analysis. The samples cover 38 parameters at up to three concentration levels that are typical for environmental water. The

Jill Merry

1993-01-01

9

Quality control for diagnostic oral microbiology laboratories in European countries  

PubMed Central

Participation in diagnostic microbiology internal and external quality control (QC) processes is good laboratory practice and an essential component of a quality management system. However, no QC scheme for diagnostic oral microbiology existed until 2009 when the Clinical Oral Microbiology (COMB) Network was created. At the European Oral Microbiology Workshop in 2008, 12 laboratories processing clinical oral microbiological samples were identified. All these were recruited to participate into the study and six laboratories from six European countries completed both the online survey and the first QC round. Three additional laboratories participated in the second round. Based on the survey, European oral microbiology laboratories process a significant (mean per laboratory 4,135) number of diagnostic samples from the oral cavity annually. A majority of the laboratories did not participate in any internal or external QC programme and nearly half of the laboratories did not have standard operating procedures for the tests they performed. In both QC rounds, there was a large variation in the results, interpretation and reporting of antibiotic susceptibility testing among the laboratories. In conclusion, the results of this study demonstrate the need for harmonisation of laboratory processing methods and interpretation of results for oral microbiology specimens. The QC rounds highlighted the value of external QC in evaluating the efficacy and safety of processes, materials and methods used in the laboratory. The use of standardised methods is also a prerequisite for multi-centre epidemiological studies that can provide important information on emerging microbes and trends in anti-microbial susceptibility for empirical prescribing in oro-facial infections.

Rautemaa-Richardson, Riina; der Reijden Wa, Wil A Van; Dahlen, Gunnar; Smith, Andrew J.

2011-01-01

10

Implementing comprehensive quality control in the andrology laboratory.  

PubMed

Comprehensive quality control procedures were integrated into the routine semen analysis workload of a large university-based andrology laboratory. Methods were chosen to match as far as possible those which have been used successfully for many years in disciplines such as clinical chemistry. Levey-Jennings and cusum charts were plotted in order to monitor the immunobead-binding test for antisperm antibodies and a video-taped control sample for computerized semen analysis. A cryopreserved semen control was also charted. Daily manual sperm counts were plotted against the corresponding computer-assisted semen analysis (CASA) value. Multiple readings of 30 slides were used to monitor morphology assessments. Monthly means for morphology were also calculated regularly. Coefficients of variation were calculated for all variables and were found to be more appropriate for some aspects, such as CASA, than for others, such as morphology, when difference from the previous reading of the same slide was found to be more useful. These integrated quality control procedures had a direct influence on the production of results from the laboratory. Together with a high standard of technician training, comprehensive routine quality control based on repeated analyses of control samples is an effective way of assuring the validity of semen analysis results. PMID:8567848

Clements, S; Cooke, I D; Barratt, C L

1995-08-01

11

[Improvement of routine works and quality control in mycobacterial laboratory].  

PubMed

Many new methods have been introduced into routine laboratory works in microbiology since 1990. Molecular biology, in particular, opened a new era and promoted a technician's skill much. PCR and hybridization technique have been ordinary one in many laboratories. Since old techniques such as smear and culture are still needed, amount of routine works is increasing gradually. Thus, improving efficiency and keeping quality of routine works are becoming more and more important issues. This symposium focused on such points, and four skilled technicians around Japan presented their own tips. 1. Coexistence of M. tuberculosis and M. avium complex (MAC) in the MGIT culture system: Yasushi WATANABE (Clinical Laboratory Division, NHO Nishi-Niigata Chuo National Hospital). Sputum samples of some tuberculosis patients yielded only MAC in the MGIT culture system. Such co-infected cases presented problems to mislead proper treatment and infection control. The detection rate of MAC was significantly high, and the growth speed of MAC was significantly rapid in the MGIT culture system, compared to those of M. tuberculosis. Additionally, M. tuberculosis was not detected with even more quantity than MAC in the small amount of mixed samples. Higher sensitivity and growth speed of MAC are the important characteristics of the MGIT system. 2. Internal quality control with ordinary examination results: Akio AONO (Department of Clinical Examination, Double-Barred Cross Hospital, Japan Anti-Tuberculosis Association). Our laboratory utilizes ordinary examination results as the internal quality control for specimen pretreatment, culture, and drug susceptibility testing. The contamination rate of MGIT culture system is useful for the evaluation of the decontamination process. It was 6.3% on average in our laboratory in 2005. The number of drug resistant strains is also useful to assess the performance of drug susceptibility testing. The incidence of each anti-tuberculosis drug resistance detected monthly in 2005 is up to 5 for isoniazid (INH), 4 for rifampicin (RFP), 7 for streptomycin (SM), 1 for ethambutol (EB), and 2 for pyrazinamide (PZA), respectively. If any serious deviation from the average number is observed, action for the investigation is taken. The analysis of the ordinary examination data is useful to implement a quality control efficiently, and to improve the total laboratory performance. 3. The advanced devices for solving problems of the smears and cultivation of Mycobacteria: Motohisa TOMITA (NHO Kinki-chuo Chest Medical Center). Recently, the newly developed, standardized, commercially available kits including PCR and liquid media for confirmation and identification of mycobacteria are prevalent in Japan for the rapid diagnosis of M. tuberculosis. These tests are sensitive and accurate, but still expensive and technically demanding. The improvement of these methods, in particular, requires time-consuming process. We have optimized the culture technique, the identification method, and the drug-susceptibility testing for Mycobacteria in a time-saving manner. They should provide a basic grounding in the application of the techniques for anyone who is interested in these intriguing bacteria. 4. Ultimate quality control of specimens--teaching how to get a good sputum sample: Takeshi HIGUCHI (Kyoto University Hospital). Modern techniques including molecular biology have been applied to routine laboratory works for rapid detection, identification, and drug susceptibility testing of mycobacteria. Even in using such techniques, however, poor quality specimens yield only poor results. To get a high quality specimen, particularly sputum samples, is very important. Therefore, laboratory technicians in our hospital have directly taught each patient how to expectorate good quality sputa since 2001. The teaching of patients has improved the rate of P1 samples from 21.5% to 36.6% by Miller and Jones visual score of sputum. The teaching has also improved the rate of smear positive P1 samples from 11.4% to 28.8%. To teach each patient how to get go

Suzuki, Katsuhiro; Higuchi, Takeshi

2007-03-01

12

Quality control assessment of Canadian laboratories testing for Lyme disease.  

PubMed

In June 1990 a quality control assessment was undertaken of Canadian public health laboratories testing for antibodies to Borrelia burgdorferi, the etiological agent of Lyme disease. Twenty sera were distributed to nine laboratories, including 12 obtained from patients in Lyme endemic areas and presumed to be serological positives, and eight prescreened negative controls. Seventeen serological reports were submitted, comprising nine enzyme-linked immunosorbent assays (elisa), six immunofluorescent assays and two Western blot assessments. Antibodies were detected in 11 of the 12 sera which had been presumed to be positive. Assuming 11 positive sera had been submitted, the test sensitivities varied from 88.9 to 100% by elisa, and 54.5 to 90.1% by immunofluorescent assay. Specificities were 100% for all but one elisa and one immunofluorescent assay assessment. The results indicate a satisfactory performance by elisa but a need for upgrading or replacement of some immunofluorescent assay tests. PMID:22451751

Artsob, H; Garvie, M

1991-01-01

13

A GUIDE ON INTERNAL QUALITY CONTROL AND QUALITY ASSURANCE FOR TANZANIA NATIONAL FISH QUALITY CONTROL LABORATORY  

Microsoft Academic Search

Results from laboratories are important to facilitate import and export of goods including food. It is therefore of prime importance that the laboratory is capable of performing its tasks and accreditation is one way of determining that. The ISO 17025 standard describes the \\

Ofred J. M. Mhongole

14

ENERGY EFFICIENT AIR QUALITY CONTROL IN LABORATORIES USING BENCH EXHAUSTS  

Microsoft Academic Search

The air quality in laboratories has a profound affect on occupant health and safety. Reducing the time of exposure and the amount of contaminant can improve the occupant environment and have direct impact on health and safety. In this study, a novel ventilation system which introduces bench exhausts is proposed. The system offers the potential for application in new and

Farhad Memarzadeh; Jane Jiang; Andy Manning

15

Introducing Quality Control in the Chemistry Teaching Laboratory Using Control Charts  

ERIC Educational Resources Information Center

Quality control (QC) measures are less prevalent in teaching laboratories than commercial settings possibly owing to a lack of commercial incentives or teaching resources. This article focuses on the use of QC assessment in the analytical techniques of high performance liquid chromatography (HPLC) and ultraviolet-visible spectroscopy (UV-vis) at…

Schazmann, Benjamin; Regan, Fiona; Ross, Mary; Diamond, Dermot; Paull, Brett

2009-01-01

16

ASVCP quality assurance guidelines: control of general analytical factors in veterinary laboratories.  

PubMed

Owing to lack of governmental regulation of veterinary laboratory performance, veterinarians ideally should demonstrate a commitment to self-monitoring and regulation of laboratory performance from within the profession. In response to member concerns about quality management in veterinary laboratories, the American Society for Veterinary Clinical Pathology (ASVCP) formed a Quality Assurance and Laboratory Standards (QAS) committee in 1996. This committee recently published updated and peer-reviewed Quality Assurance Guidelines on the ASVCP website. The Quality Assurance Guidelines are intended for use by veterinary diagnostic laboratories and veterinary research laboratories that are not covered by the US Food and Drug Administration Good Laboratory Practice standards (Code of Federal Regulations Title 21, Chapter 58). The guidelines have been divided into 3 reports on 1) general analytic factors for veterinary laboratory performance and comparisons, 2) hematology and hemostasis, and 3) clinical chemistry, endocrine assessment, and urinalysis. This report documents recommendations for control of general analytical factors within veterinary clinical laboratories and is based on section 2.1 (Analytical Factors Important In Veterinary Clinical Pathology, General) of the newly revised ASVCP QAS Guidelines. These guidelines are not intended to be all-inclusive; rather, they provide minimum guidelines for quality assurance and quality control for veterinary laboratory testing. It is hoped that these guidelines will provide a basis for laboratories to assess their current practices, determine areas for improvement, and guide continuing professional development and education efforts. PMID:21054473

Flatland, Bente; Freeman, Kathy P; Friedrichs, Kristen R; Vap, Linda M; Getzy, Karen M; Evans, Ellen W; Harr, Kendal E

2010-09-01

17

An approach to quality and performance control in a computer-assisted clinical chemistry laboratory.  

PubMed Central

A locally developed, computer-based clinical chemistry laboratory system has been in operation since 1970. This utilises a Digital Equipment Co Ltd PDP 12 and an interconnected PDP 8/F computer. Details are presented of the performance and quality control techniques incorporated into the system. Laboratory performance is assessed through analysis of results from fixed-level control sera as well as from cumulative sum methods. At a simple level the presentation may be considered purely indicative, while at a more sophisticated level statistical concepts have been introduced to aid the laboratory controller in decision-making processes.

Undrill, P E; Frazer, S C

1979-01-01

18

Application of indices cp and cpk to improve quality control capability in clinical biochemistry laboratories.  

PubMed

The traditional criteria for acceptability of analytic quality may not be objective in clinical laboratories. To establish quality control procedures intended to enhance Westgard multi-rules for improving the quality of clinical biochemistry tests, we applied the Cp and Cpk quality-control indices to monitor tolerance fitting and systematic variation of clinical biochemistry test results. Daily quality-control data of a large Taiwanese hospital in 2009 were analyzed. The test items were selected based on an Olympus biochemistry machine and included serum albumin, aspartate aminotransferase, cholesterol, glucose and potassium levels. Cp and Cpk values were calculated for normal and abnormal levels, respectively. The tolerance range was estimated with data from 50 laboratories using the same instruments and reagents. The results showed a monthly trend of variation for the five items under investigation. The index values of glucose were lower than those of the other items, and their values were usually <2. In contrast to the Cp value for cholesterol, Cpk of cholesterol was lower than 2, indicating a systematic error that should be further investigated. This finding suggests a degree of variation or failure to meet specifications that should be corrected. The study indicated that Cp and Cpk could be applied not only for monitoring variations in quality control, but also for revealing inter-laboratory qualitycontrol capability differences. PMID:24694196

Chen, Ming-Shu; Wu, Ming-Hsun; Lin, Chih-Ming

2014-04-30

19

Analytical laboratory quality audits  

SciTech Connect

Analytical Laboratory Quality Audits are designed to improve laboratory performance. The success of the audit, as for many activities, is based on adequate preparation, precise performance, well documented and insightful reporting, and productive follow-up. Adequate preparation starts with definition of the purpose, scope, and authority for the audit and the primary standards against which the laboratory quality program will be tested. The scope and technical processes involved lead to determining the needed audit team resources. Contact is made with the auditee and a formal audit plan is developed, approved and sent to the auditee laboratory management. Review of the auditee's quality manual, key procedures and historical information during preparation leads to better checklist development and more efficient and effective use of the limited time for data gathering during the audit itself. The audit begins with the opening meeting that sets the stage for the interactions between the audit team and the laboratory staff. Arrangements are worked out for the necessary interviews and examination of processes and records. The information developed during the audit is recorded on the checklists. Laboratory management is kept informed of issues during the audit so there are no surprises at the closing meeting. The audit report documents whether the management control systems are effective. In addition to findings of nonconformance, positive reinforcement of exemplary practices provides balance and fairness. Audit closure begins with receipt and evaluation of proposed corrective actions from the nonconformances identified in the audit report. After corrective actions are accepted, their implementation is verified. Upon closure of the corrective actions, the audit is officially closed.

Kelley, William D.

2001-06-11

20

Performance of automated slidemakers and stainers in a working laboratory environment - routine operation and quality control  

PubMed Central

The automated slidemaker/stainers of the four Beckman Coulter LH755 hematology systems in our laboratory are operated as analyzers, with similar requirements for setup, maintenance and quality control. A study was performed to confirm that these slide maker/stainers in routine use produce peripheral blood films that are completely satisfactory for microscopy and without cells, particularly abnormal cells, being pulled to the edges or sides of the film outside the usual working area. One hundred and thirty-nine automated blood films that had been produced during routine operation were compared with well-prepared manual films from the same patients. None of the films was unacceptable for microscopy. The distributions of normal white cell types within the counting areas of automated films compared with manual films, for all 139 samples for WBC from 1.0 to 352.8 × 109/l; for blasts and promyelocytes in the 65 samples in which they occurred and for nucleated red blood cells in the 58 samples in which they occurred all fell within the expected limits of 200 cell differential counts of CLSI H20-A. Red cell morphology and the occurrence of WBC clumps, platelet clumps and smudge cells were comparable between the automated and manual films of all samples. We conclude that automated slidemaker/stainers, as typified by those of the Beckman Coulter LH755 system, are capable of producing blood films comparable with well-prepared manual films in routine laboratory use; and that the maintenance and quality control procedures used in our laboratory ensure consistent high quality performance from these systems.

SIMSON, E; GASCON-LEMA, M G; BROWN, D L

2010-01-01

21

A Preliminary Clinical Chemistry Laboratory Quality Control Programme for Addis Ababa.  

National Technical Information Service (NTIS)

A serum pool programme in clinical chemistry was started in Addis Ababa as a control for 5 participating laboratories. Basic statistical indices were calculated to determine the variation within each laboratory and to compare interlaboratory results. Stat...

C. P. Fulass R. Gillum

1973-01-01

22

[System of internal laboratory control over the quality of clinical biochemical research].  

PubMed

An analysis and testing of the system of on-laboratory control on the quality of biochemical investigations with the use of control cards, has been performed. The system provides for the working out of control cards, the carrying out of control investigations, the evaluation of the results, and the correction of the control cards. Data for the built-up of the cards has been obtained with the practice of as many as 30 replications with one and the same sample, under the same conditions, the values of the average quadratic deviation (S) being in compliance with Tonks criterion. The action of control is substantiated through doubling the study of 10 per cent of the samples of each batch for each analysis and evaluation of the differences with regard to S by a two-mark system. An average mark from 0.00 to 2.00 per batch of samples is formed for each analysis. Filled in control cards for the total calcium and inorganic phosphorus are presented as an example. The changes in the S values are followed up after the introduction of control cards for 9 indices. With 7 indices reproducibility has proved higher. A total of 90 series of analyses have been controlled and evaluated--54 series (60 per cent) have proved 'good' (from 1.5 to 2.00), 22 series (24.44 per cent)--'satisfactory' (from 1.00 to 1.49), and 14 series (15.56 per cent)--'bad' (from 0.00 to 1.00 or at differences greater than 2.5 S) which implied that the respective analyses of the series of samples had to be replicated. A total of 24 control cards for various indices have been built up. PMID:3617472

Marinov, S; Tsvetkova, R; Parashkevova, E

1987-01-01

23

Quality Control  

Microsoft Academic Search

\\u000a Quality control can de divided in production control, process control, and product control. The first two refer to internal\\u000a quality control of the production of a microbial pest control product, and ensure a stable production process with a minimum\\u000a of failures. Product control refers to the quality of the final product that leaves the factory and which needs to perform

Willem J. Ravensberg

24

Quality Control Guidelines for National Committee for Clinical Laboratory Standards Recommended Broth Macrodilution Testing of Amphotericin B, Fluconazole, and Flucytosine  

Microsoft Academic Search

Amphotericin B, fluconazole, and flucytosine (5FC) were tested in a multilaboratory study to establish quality control (QC) guidelines for yeast antifungal susceptibility testing. Ten candidate QC strains were testedinaccordancewithNationalCommitteeforClinicalLaboratoryStandardsM27-Pguidelinesagainstthe three antifungal agents in each of six laboratories. Each laboratory was assigned a unique lot of RPMI 1640 broth medium as well as a lot of RPMI 1640 common to all

M. A. PFALLER; M. BALE; B. BUSCHELMAN; M. LANCASTER; A. ESPINEL-INGROFF; J. H. REX; M. G. RINALDI; C. R. COOPER; R. MCGINNIS

1995-01-01

25

Interlaboratory quality control  

Microsoft Academic Search

The goal of every analytical laboratory and of every analyst is to produce highly precise and accurate analyses in a timely and cost effective manner. Quality assurance must be an intregal part of any laboratory's standard operating procedures to insure the precision and accuracy of analyses. Interlaboratory quality assurance is important. The primary purpose of the quality control group is

2009-01-01

26

Microarray-based genetic identification of beneficial organisms as a new tool for quality control of laboratory cultures  

Microsoft Academic Search

The use of beneficial organisms to help control pests and pathogens in field and greenhouse crops is constantly increasing. Insects and mites are commonly used as beneficial organisms and, nowadays, rearing companies have to produce them in large quantities. Because of the peculiarities of laboratory culture conditions, the quality of lab-reared organisms generally degrades over time. To maintain high fitness

Frédérique Pasquer; Monika Pfunder; Beatrice Frey; Juerg E. Frey

2009-01-01

27

Reliability of nucleic acid amplification for detection of Mycobacterium tuberculosis: an international collaborative quality control study among 30 laboratories.  

PubMed

Nucleic acid amplification to detect Mycobacterium tuberculosis in clinical specimens is increasingly used as a laboratory tool for the diagnosis of tuberculosis. However, the specificity and sensitivity of these tests may be questioned, and no standardized reagents for quality control assessment are available. To estimate the performance of amplification tests for routine diagnosis, we initiated an interlaboratory study involving 30 laboratories in 18 countries. We prepared blinded panels of 20 sputum samples containing no, 100, or 1,000 mycobacterial cells. Each laboratory was asked to detect M. tuberculosis by their routine method of nucleic acid amplification. Only five laboratories correctly identified the presence or absence of mycobacterial DNA in all 20 samples. Seven laboratories detected mycobacterial DNA in all positive samples, and 13 laboratories correctly reported the absence of DNA in the negative samples. Lack of specificity was more of a problem than lack of sensitivity. Reliability was not found to be associated with the use of any particular method. Reliable detection of M. tuberculosis in clinical samples by nucleic acid amplification techniques is possible, but many laboratories do not use adequate quality controls. This study underlines the need for good laboratory practice and reference reagents to monitor the performance of the whole assay, including pretreatment of clinical samples. PMID:8880513

Noordhoek, G T; van Embden, J D; Kolk, A H

1996-10-01

28

Microbiological collaborative studies for quality control in food laboratories: reference material and evaluation of analyst's errors.  

PubMed

Working groups of the Federal Health Office in Germany and of the International Dairy Federation (IDF) have developed a quality assurance system to assess the analyst performance for colony count methods. The experiment design consists of several dilution series produced from a homogeneous sample suspension. Each series contains a number of twofold dilution steps with parallel plates on each level. The structure of this design permits a detailed analysis of the total variance and identification of analysts' methodological errors as single effects. A computer-based interpretation aid may classify the laboratory as working in correspondence with good laboratory practice ('acceptable') or, otherwise, furnishing 'to good' or 'unacceptable' results. Some examples are given for deviation depending on individual faults. Both, internal quality assurance and collaborative studies demand suitable reference samples. The reference material used has to meet certain requirements concerning homogeneity, contamination level and microbiological stability during a period of storage and transport. A naturally contaminated sample material was prepared, which has been used successfully in microbiological collaborative studies. PMID:7703029

Berg, C; Dahms, S; Hildebrandt, G; Klaschka, S; Weiss, H

1994-12-01

29

Implementation of air quality control in reproductive laboratories in full compliance with the Brazilian Cells and Germinative Tissue Directive.  

PubMed

This article describes how Androfert complied with the Brazilian Cells and Germinative Tissue Directive with regard to air quality standards and presents retrospective data of intracytoplasmic sperm injection (ICSI) outcomes performed in controlled environments. An IVF facility, composed of reproductive laboratories, operating room and embryo-transfer room, was constructed according to cleanroom standards for air particles and volatile organic compounds. A total of 2060 couples requesting IVF were treated in the cleanroom facilities, and outcome measures compared with a cohort of 255 couples treated at a conventional facility from the same practice before implementation of cleanrooms. No major fluctuations were observed in the cleanroom validation measurements over the study period. Live birth rates increased (35.6% versus 25.8%; P=0.02) and miscarriage rates decreased (28.7% versus 20.0%; P=0.04) in the first triennium after cleanroom implementation. Thereafter, the proportion of high-quality embryos steadily increased whereas pregnancy outcomes after ICSI were sustained despite the increased female age and decreased number of embryos transferred. This study demonstrates the feasibility of handling human gametes and culturing embryos in full compliance with the Brazilian directive on air quality standards and suggests that performing IVF in controlled environments may optimize its outcomes. Regulatory agencies in many countries have issued directives including specific requirements for air quality standards in embryology facilities. This article describes how we complied with the Brazilian Cells and Germinative Tissue Directive with regard to air quality standards. It also presents results of IVF cycles performed in controlled environments. An IVF facility, composed of reproductive laboratories, operating room and embryo transfer room, was constructed according to cleanroom standards for air particles and volatile organic compounds. The cleanest area was the embryology laboratory, followed by the operating room and embryo transfer room. A total of 2060 couples requesting IVF were treated in the cleanroom facilities, and outcome measures compared with a cohort of 255 couples treated at a conventional facility. Live birth rates increased by 37% and miscarriage rates decreased by 30% in the first triennium after cleanroom implementation. Thereafter, the proportion of high-quality embryos steadily increased whereas pregnancy outcomes after ICSI were sustained despite the increased female age and decreased number of embryos transferred. We demonstrate the feasibility of handling human gametes and culturing embryos in full compliance with the Brazilian Directive on air quality standards and suggest that performing IVF in controlled environments may optimize its outcomes. PMID:23177417

Esteves, Sandro C; Bento, Fabiola C

2013-01-01

30

Comparison of quality-control rules used in clinical chemistry laboratories.  

PubMed

Numerous papers have been written to show which combinations of Shewhart-type quality-control charts are optimal for detecting systematic shifts in the mean response of a process, increases in the random error of a process, and linear drift effects in the mean response across the assay batch. One paper by Westgard et al. (Clin Chem 1977;23:1857-67) especially seems to have attracted the attention of users. Here we derive detailed results that enable the characteristics of the various Shewhart-type control schemes, including the multirule scheme (Clin Chem 1981;27:493-501), to be calculated and show that a fundamental formula proposed by Westgard et al. in the earlier paper is in error, although their derived results are not seriously wrong. We also show that, from a practical point of view, a suitably chosen Cusum scheme is near optimal for all the types and combinations of errors discussed, thereby removing the selection problem for the user. PMID:8353950

Bishop, J; Nix, A B

1993-08-01

31

[Approval of ISO/IEC 17025 and quality control of laboratory testing].  

PubMed

First section of Division of Biomedical Food Research, National Institute of Health Sciences (NIHS) was approved by ISO/IEC 17025 as a laboratory having an appropriate laboratory testing technique. NIHS is the first national laboratory approved by ISO/IEC 17025. NIHS has also been accepted the appropriate technique and facility for the BSL3 level pathogens by ISO/IEC 17025. NIHS is necessary to take an external audit almost every year. This approval is renewed every 4 years. PMID:21381399

Yamamoto, Shigeki; Asakura, Hiroshi; Machii, Kenji; Igimi, Shizunobu

2010-01-01

32

[Quality management in medical laboratories].  

PubMed

During the 20th century understanding for quality has changed and international and national requirements for quality have been published. Therefore also medical branches started to establish quality management systems. Quality assurance has always been important for medical laboratories. Certification according to the standard ISO 9001 and accreditation according to the standard ISO 17025 have been the proof of fulfilling quality requirements. The relatively new standard ISO 15189 is the first standard for medical laboratories. This standard includes technical and management requirements for the medical laboratory. The main focus is the proof of competence within the personnel. As this standard is accepted throughout the European Union an increase in accreditations of medical laboratories is predictable. PMID:20454753

Fritzer-Szekeres, M

2010-05-01

33

Effect of leachate recirculation on landfill gas production and leachate quality: A controlled laboratory study  

Microsoft Academic Search

This report summarizes the results of a laboratory study conducted during 1992-1994 at Argonne National Laboratory. The study examined biogas production and leachate chemistry in parallel anaerobic assays run under either leachate recycle or leachate drainage regimes over a period of 400 days. A standardized synthetic refuse (paper, grass, food) was used in an experimental design which evaluated two elevated

J. Bogner; K. Spokas

1995-01-01

34

SEAPAL quality control analysis of rheumatoid factor measurement in 29 diagnostic laboratories  

Microsoft Academic Search

A programme for rheumatoid factor (RF) measurement was sponsored by the South East Asian Pacific League against Rheumatism (SEAPAL) and the Clinical Immunology Group (CIG) of the Australian Society for Immunology. Measurements in 29 laboratories in 12 countries showed: a large variety of methods were being used to measure RF, most using semiquantitative agglutination techniques; some laboratories have invalid techniques;

P J Roberts-Thomson; T Langhans; R McEvoy; P N Hollingsworth; E Bonifacio; R L Dawkins; J Bradley

1987-01-01

35

21 CFR 225.58 - Laboratory controls.  

Code of Federal Regulations, 2013 CFR

21 Food and Drugs 4 2013-04-01...2013-04-01 false Laboratory controls. 225.58 Section 225.58 Food and Drugs FOOD AND DRUG ADMINISTRATION...MEDICATED FEEDS Product Quality Control § 225.58 Laboratory...

2013-04-01

36

21 CFR 226.58 - Laboratory controls.  

Code of Federal Regulations, 2013 CFR

21 Food and Drugs 4 2013-04-01...2013-04-01 false Laboratory controls. 226.58 Section 226.58 Food and Drugs FOOD AND DRUG ADMINISTRATION...MEDICATED ARTICLES Product Quality Control § 226.58 Laboratory...

2013-04-01

37

USGS: National Water Quality Laboratory  

NSDL National Science Digital Library

The USGS's "National Water Quality Laboratory (NWQL) offers environmental analytical services, including inorganic, organic, and radiochemical constituents, and provides high-quality, reproducible data." Researchers can find a summary of the Laboratory's capabilities, facilities, technology, areas of expertise, and accreditations and certificates. The website offers a Microsoft PowerPoint presentation of its mission. Users can find technical memoranda, a list of NWQL reports and journal articles, and factsheets.

38

Statistical quality control procedures.  

PubMed

The right quality control (QC) should ensure the detection of important errors. Statistical QC (SQC) should be included in all QC plans. The Clinical and Laboratory Standards Institute (CLSI) C24A3 provides guidance for the application of SQC in medical laboratories. It describes a QC planning process and provides an SQC selection tool that relates the sigma-metric of a testing process to the medically important systematic error and the rejection characteristics of different SQC procedures. Once the right SQC has been selected, the laboratory must implement SQC right. CLSI C24A3 also provides guidance for establishing run length and control limits. PMID:23331732

Westgard, James O

2013-03-01

39

Automation and quality in analytical laboratories  

SciTech Connect

After a brief introduction to the generic aspects of automation in analytical laboratories, the different approaches to quality in analytical chemistry are presented and discussed to establish the following different facets emerging from the combination of quality and automation: automated analytical control of quality of products and systems; quality control of automated chemical analysis; and improvement of capital (accuracy and representativeness), basic (sensitivity, precision, and selectivity), and complementary (rapidity, cost, and personnel factors) analytical features. Several examples are presented to demonstrate the importance of this marriage of convenience in present and future analytical chemistry. 7 refs., 4 figs.

Valcarcel, M.; Rios, A. [Univ. of Cordoba (Spain)

1994-05-01

40

Effect of leachate recirculation on landfill gas production and leachate quality: A controlled laboratory study  

SciTech Connect

This report summarizes the results of a laboratory study conducted during 1992-1994 at Argonne National Laboratory. The study examined biogas production and leachate chemistry in parallel anaerobic assays run under either leachate recycle or leachate drainage regimes over a period of 400 days. A standardized synthetic refuse (paper, grass, food) was used in an experimental design which evaluated two elevated moisture contents and two added soils. All assays were conducted in vitro in 125 mL serum bottles. Four recycle/drainage events were completed during the 400 days of this experiment. Sufficient replicates (10 or 20) for each trial were included in the experimental design to permit destructive sampling of assay solids after each recycle/drainage event. Changes in the chemistry of solid, liquid, and gaseous phases were evaluated during the decomposition process. Analyses included major gases (CH{sub 4}, CO{sub 2}, O{sub 2}, N{sub 2}), selected chemical constituents of leachate (Cl-C5 carboxylic acids, total organic carbon, Kjeldahl nitrogen, total phosphorus, iron, zinc, and chloride), leachate pH and conductivity, and selected solids analysis (gravimetric moisture content, volatile solids, total carbon, cellulose, hemicellulose, and lignin).

Bogner, J.; Spokas, K.

1995-05-01

41

ASVCP quality assurance guidelines: control of preanalytical and analytical factors for hematology for mammalian and nonmammalian species, hemostasis, and crossmatching in veterinary laboratories.  

PubMed

In December 2009, the American Society for Veterinary Clinical Pathology (ASVCP) Quality Assurance and Laboratory Standards committee published the updated and peer-reviewed ASVCP Quality Assurance Guidelines on the Society's website. These guidelines are intended for use by veterinary diagnostic laboratories and veterinary research laboratories that are not covered by the US Food and Drug Administration Good Laboratory Practice standards (Code of Federal Regulations Title 21, Chapter 58). The guidelines have been divided into 3 reports: (1) general analytical factors for veterinary laboratory performance and comparisons; (2) hematology, hemostasis, and crossmatching; and (3) clinical chemistry, cytology, and urinalysis. This particular report is one of 3 reports and provides recommendations for control of preanalytical and analytical factors related to hematology for mammalian and nonmammalian species, hemostasis testing, and crossmatching and is adapted from sections 1.1 and 2.3 (mammalian hematology), 1.2 and 2.4 (nonmammalian hematology), 1.5 and 2.7 (hemostasis testing), and 1.6 and 2.8 (crossmatching) of the complete guidelines. These guidelines are not intended to be all-inclusive; rather, they provide minimal guidelines for quality assurance and quality control for veterinary laboratory testing and a basis for laboratories to assess their current practices, determine areas for improvement, and guide continuing professional development and education efforts. PMID:22390423

Vap, Linda M; Harr, Kendal E; Arnold, Jill E; Freeman, Kathleen P; Getzy, Karen; Lester, Sally; Friedrichs, Kristen R

2012-03-01

42

Reliability of nucleic acid amplification methods for detection of Chlamydia trachomatis in urine: results of the first international collaborative quality control study among 96 laboratories  

Microsoft Academic Search

The first European Quality Control Concerted Action study was organized to\\u000a assess the ability of laboratories to detect Chlamydia trachomatis in a\\u000a panel of urine samples by nucleic acid amplification tests (NATs). The\\u000a panel consisted of lyophilized urine samples, including three negative,\\u000a two strongly positive, and five weakly positive samples. Ninety-six\\u000a laboratories in 22 countries participated with a total of

Roel P. Verkooyen; Gerda T. Noordhoek; Paul E. Klapper; Jim Reid; Jurjen Schirm; Graham M. Cleator; Margareta Ieven; Gunnar Hoddevik

2003-01-01

43

Quality and safety aspects in histopathology laboratory  

PubMed Central

Histopathology is an art of analyzing and interpreting the shapes, sizes and architectural patterns of cells and tissues within a given specific clinical background and a science by which the image is placed in the context of knowledge of pathobiology, to arrive at an accurate diagnosis. To function effectively and safely, all the procedures and activities of histopathology laboratory should be evaluated and monitored accurately. In histopathology laboratory, the concept of quality control is applicable to pre-analytical, analytical and post-analytical activities. Ensuring safety of working personnel as well as environment is also highly important. Safety issues that may come up in a histopathology lab are primarily those related to potentially hazardous chemicals, biohazardous materials, accidents linked to the equipment and instrumentation employed and general risks from electrical and fire hazards. This article discusses quality management system which can ensure quality performance in histopathology laboratory. The hazards in pathology laboratories and practical safety measures aimed at controlling the dangers are also discussed with the objective of promoting safety consciousness and the practice of laboratory safety.

Adyanthaya, Soniya; Jose, Maji

2013-01-01

44

Intelligent Fuzzy Controllers Laboratory  

Microsoft Academic Search

The Intelligent Fuzzy Controllers Laboratory has been developed in the Department of Electrical and Computer Engineering of Western Michigan University with the help of a DURIP grant by the Department of Defense (6) and generous donations by ABB Automation Technology Products. This new lab is to support research, the development of advanced courses, and graduate projects in the area of

Janos L Grantner; Ramakrishna Gottipati; George A Fodor

2004-01-01

45

Quality Control Microbiology  

NSDL National Science Digital Library

This two page PDF, created by Northeast Biomanufacturing Center and Collaborative, discusses the key functions and tasks of a quality control technician (microbiology). The document focuses mostly on: the work compliance with both EH&S and cGMPS, the cleanliness and maintenance of production areas, maintaining effective communication, receiving and/or collecting samples, laboratory work, performaning microbiological testing and culturing, managing information and providing technical and/or validation support. Each one of these topics contains anywhere from five to fifteen different subtopics. The lists are meant to give a broad overview of each one of these topics.

2009-09-24

46

Quality Control Microbiologist  

NSDL National Science Digital Library

This video, presented by WGBH, takes a look at a day in the life of a quality control microbiologist at a pharmaceutical company and provides a detailed account of what is possible with a microbiology degree, including the hands-on laboratory aspects field. This video would be helpful for anyone interested in a degree in microbiology, as well as anyone that is currently earning a degree in this field but is still unsure about what to do with it. Educators will also find a background essay, discussion questions, and standards alignment for the material. Running time for the video is 2:38.

2010-10-12

47

Characterization of laboratory working standard for quality control of immunometric and radiometric estrogen receptor assays. Clinical evaluation on breast cancer biopsies. Italian Committee for Hormone Receptor Assays Standardization.  

PubMed

The objective of the study was to characterize a low-cost and reliable working standard material for quality control of estrogen receptor (ER) determination with dextran-coated charcoal (DCC) and enzyme immunoassay (EIA) methods. Human fibromatous uterine lyophilized cytosol demonstrated good characteristics of stability and applicability for this purpose. Eleven laboratories participated in the intralaboratory and interlaboratory quality control study, and they achieved slightly higher coefficients of variation for ER-EIA (interlaboratory, 37.7%; intralaboratory, 22.9%) than for ER-DCC (interlaboratory, 24.2%; intralaboratory, 15.7%). There was an excellent correlation between ER results with ER-EIA and ER-DCC for 268 breast cancer biopsies. Quality assurance for ER assays using DCC techniques and immunometric methods with monoclonal antibodies (ER-EIA) can be set up with this available material of human origin to satisfy the characteristics of both techniques and the species specificity of monoclonal antibodies. PMID:2482565

Piffanelli, A; Pelizzola, D; Giovannini, G; Catozzi, L; Faggioli, L; Giganti, M

1989-12-31

48

Evaluation of quality assurance/quality control data collected by the U.S. Geological Survey for water-quality activities at the Idaho National Engineering and Environmental Laboratory, Idaho, 1994 through 1995  

SciTech Connect

More than 4,000 water samples were collected by the US Geological Survey (USGS) from 179 monitoring sites for the water-quality monitoring program at the Idaho National Engineering Laboratory from 1994 through 1995. Approximately 500 of the water samples were replicate or blank samples collected for the quality assurance/quality control program. Analyses were performed to determine the concentrations of major ions, nutrients, trace elements, gross radioactivity and radionuclides, total organic carbon, and volatile organic compounds in the samples. To evaluate the precision of field and laboratory methods, analytical results of the replicate pairs of samples were compared statistically for equivalence on the basis of the precision associated with each result. In all, the statistical comparison of the data indicated that 95% of the replicate pairs were equivalent. Within the major ion analyses, 97% were equivalent; nutrients, 88%; trace elements, 95%; gross radioactivity and radionuclides, 93%; and organic constituents, 98%. Ninety percent or more of the analytical results for each constituent were equivalent, except for nitrite, orthophosphate, phosphorus, aluminum, iron, strontium-90, and total organic carbon.

Williams, L.M.

1997-03-01

49

ELEMENTS OF A LABORATORY QUALITY ASSURANCE PROGRAM  

EPA Science Inventory

The importance of Quality Assurance is discussed. The requirements of a quality assurance program are divided into three functions; namely, the Control of Quality, the Determination of Quality, and the Documentation of Quality. The Control of Quality is defined as the regulation ...

50

Quality Leadership and Quality Control  

PubMed Central

Different quality control rules detect different analytical errors with varying levels of efficiency depending on the type of error present, its prevalence and the number of observations. The efficiency of a rule can be gauged by inspection of a power function graph. Control rules are only part of a process and not an end in itself; just as important are the trouble-shooting systems employed when a failure occurs. 'Average of patient normals' may develop as a usual adjunct to conventional quality control serum based programmes. Acceptable error can be based on various criteria; biological variation is probably the most sensible. Once determined, acceptable error can be used as limits in quality control rule systems. A key aspect of an organisation is leadership, which links the various components of the quality system. Leadership is difficult to characterise but its key aspects include trust, setting an example, developing staff and critically setting the vision for the organisation. Organisations also have internal characteristics such as the degree of formalisation, centralisation, and complexity. Medical organisations can have internal tensions because of the dichotomy between the bureaucratic and the shadow medical structures.

Badrick, Tony

2003-01-01

51

Laboratory quality improvement in Thailand's northernmost provinces  

Microsoft Academic Search

Purpose – In Thailand nearly 1,000 public health laboratories serve 65 million people. A qualified indicator of a good quality laboratory is Thailand Medical Technology Council certification. Consequently, Chiang Rai Regional Medical Sciences Center established a development program for laboratory certification for 29 laboratories in the province. This paper seeks to examine this issue. Design\\/methodology\\/approach – The goal was to

S. Kanitvittaya; U. Suksai; O. Suksripanich; V. Pobkeeree

2010-01-01

52

[Quality controls in medical mycology].  

PubMed

The Quality Management System in medical mycology refers to the systematic monitoring with internal and external quality controls: it needs to be organized in the laboratory. ISO 15189 standard is not precise in how to demonstrate the correctness of tests, in terms of frequency and requirements for quality controls QC. That's why the COFRAC, the French Accreditation Committee has published guides to which we should refer. The laboratory has to apply internal Quality Control Programs. They consist of various tests to check the reagents including the culture media. Reference strains have to be provided and preparations of homemade reagents are needed, because few are commercialized. Maintaining the competence of the technical staff through identification of unknown strains is also required. In the fungal serology field, home made antibodies with pooled sera or antigen controls are needed. This monitoring has to follow the recommandations from the Cofrac technical guide LAB GTA 06. For quantitative analysis, the Levey-Jennings chart is a graph with quality control data plotted on to give a visual indication. Some external QC references, besides the national quality control AFSSAPS, are available. Data evaluation, corrective actions in case of out of range results and preventive actions have to be determined in the Quality System documents and presented in the annual management review. PMID:24451497

Kauffmann-Lacroix, C; Cassaing, S; Bessieres, M-H; Mayet, D; Linas, M-D; Roques, C

2011-03-01

53

1990 National Water Quality Laboratory Services Catalog  

USGS Publications Warehouse

PREFACE This catalog provides information about analytical services available from the National Water Quality Laboratory (NWQL) to support programs of the Water Resources Division of the U.S. Geological Survey. To assist personnel in the selection of analytical services, the catalog lists cost, sample volume, applicable concentration range, detection level, precision of analysis, and preservation techniques for samples to be submitted for analysis. Prices for services reflect operationa1 costs, the complexity of each analytical procedure, and the costs to ensure analytical quality control. The catalog consists of five parts. Part 1 is a glossary of terminology; Part 2 lists the bottles, containers, solutions, and other materials that are available through the NWQL; Part 3 describes the field processing of samples to be submitted for analysis; Part 4 describes analytical services that are available; and Part 5 contains indices of analytical methodology and Chemical Abstract Services (CAS) numbers. Nomenclature used in the catalog is consistent with WATSTORE and STORET. The user is provided with laboratory codes and schedules that consist of groupings of parameters which are measured together in the NWQL. In cases where more than one analytical range is offered for a single element or compound, different laboratory codes are given. Book 5 of the series 'Techniques of Water Resources Investigations of the U.S. Geological Survey' should be consulted for more information about the analytical procedures included in the tabulations. This catalog supersedes U.S. Geological Survey Open-File Report 86-232 '1986-87-88 National Water Quality Laboratory Services Catalog', October 1985.

Edited by Pritt, Jeffrey; Jones, Berwyn E.

1989-01-01

54

The effect of empowerment on the self-efficacy, quality of life and clinical and laboratory indicators of patients treated with hemodialysis: a randomized controlled trial  

PubMed Central

Background Hemodialysis patients face numerous physical and psychological stresses that result in reduced health. The aim of this study is to determine the impact of an empowerment program on self-efficacy, quality of life, clinical indicators of blood pressure and interdialytic weight gain, and laboratory results in these patients. Methods This randomized, controlled trial was conducted at Boo Ali Sina Dialysis Center, Shiraz, Iran. A total of 48 hemodialysis patients participated in this study. After acquisition of informed consent, eligible patients were randomly divided into two groups, control and experimental. Pre-test data were obtained by using a demographic data form and two questionnaires for self-efficacy and quality of life. Blood pressure and interdialytic weight gain were measured. We extracted laboratory data from patients’ charts. A six-week empowerment intervention that included four individual and two group counselling sessions was performed for the experimental group. Six weeks after intervention, post-test data were obtained from both groups in the same manner as the pre-test. Data were analyzed by ANCOVA using SPSS v11.5. Results There were no statistically significant differences in demographic variables between the groups. Pre-test mean scores for self-efficacy, quality of life, blood pressure, interdialytic weight gain and laboratory results did not differ between the groups. There was a significant difference between the experimental and control groups in terms of pre-to post-intervention changes in overall self-efficacy scores, stress reduction, and decision making, in addition to overall quality of life and all dimensions included within quality of life based on this questionnaire. Additionally, the pre- to post-intervention changes in systolic/diastolic blood pressures, interdialytic weight gain, hemoglobin and hematocrit levels significantly differed between the groups. Conclusion Our study demonstrates that a combination of individual and group empowerment counselling sessions improves self-efficacy, quality of life, clinical signs, and hemoglobin and hematocrit levels in hemodialysis patients. Empowerment of hemodialysis patients should be considered in hemodialysis centers to assist patients with the management of their health-related problems. Trial registration Irct ID: IRCT138901172621N4

2012-01-01

55

Methods of analysis by the U.S. Geological Survey National Water Quality Laboratory; processing, taxonomy, and quality control of benthic macroinvertebrate samples  

USGS Publications Warehouse

Qualitative and quantitative methods to process benthic macroinvertebrate (BMI) samples have been developed and tested by the U.S. Geological Survey?s National Water Quality Laboratory Biological Group. The qualitative processing method is based on visually sorting a sample for up to 2 hours. Sorting focuses on attaining organisms that are likely to result in taxonomic identifications to lower taxonomic levels (for example, Genus or Species). Immature and damaged organisms are also sorted when they are likely to result in unique determinations. The sorted sample remnant is scanned briefly by a second person to determine if obvious taxa were missed. The quantitative processing method is based on a fixed-count approach that targets some minimum count, such as 100 or 300 organisms. Organisms are sorted from randomly selected 5.1- by 5.1-centimeter parts of a gridded subsampling frame. The sorted remnant from each sample is resorted by a second individual for at least 10 percent of the original sort time. A large-rare organism search is performed on the unsorted remnant to sort BMI taxa that were not likely represented in the sorted grids. After either qualitatively or quantitatively sorting the sample, BMIs are identified by using one of three different types of taxonomic assessment. The Standard Taxonomic Assessment is comparable to the U.S. Environmental Protection Agency Rapid Bioassessment Protocol III and typically provides Genus- or Species-level taxonomic resolution. The Rapid Taxonomic Assessment is comparable to the U.S. Environmental Protection Agency Rapid Bioassessment Protocol II and provides Familylevel and higher taxonomic resolution. The Custom Taxonomic Assessment provides Species-level resolution whenever possible for groups identified to higher taxonomic levels by using the Standard Taxonomic Assessment. The consistent use of standardized designations and notes facilitates the interpretation of BMI data within and among water-quality studies. Taxonomic identifications are quality assured by verifying all referenced taxa and randomly reviewing 10 percent of the taxonomic identifications performed weekly by Biological Group taxonomists. Taxonomic errors discovered during this review are corrected. BMI data are reviewed for accuracy and completeness prior to release. BMI data are released phylogenetically in spreadsheet format and unprocessed abundances are corrected for laboratory and field subsampling when necessary.

Moulton, Stephen R., II; Carter, James L.; Grotheer, Scott A.; Cuffney, Thomas F.; Short, Terry M.

2000-01-01

56

Integration of Quality Assurance\\/Quality Control into Quantitative Analysis  

Microsoft Academic Search

Modern laboratories, be they in government or industry, operate under strict quality assurance and quality control (QA\\/QC) guidelines. Yet, these topics are rarely covered in undergraduate laboratories, or are presented as isolated experiments. This fosters the false idea that QA\\/QC is a separate subject when in actuality it is an integral part of analytical chemistry. It is possible to incorporate

Suzanne C. Bell; Jeff Moore

1998-01-01

57

On the use of (127)Xe standards for the quality control of CTBTO noble gas stations and support laboratories.  

PubMed

(127)Xe has a longer half-life than (131m)Xe, it can be easily purely produced and it is present in the environment at very low level. For these reasons, (127)Xe is supposed to be a convenient quality control radionuclide for remote noble gas stations of the International Monitoring System (IMS) network. As CEA/DAM has recently developed two new photon/electron setups for low-level detection of (131m)Xe, (133m)Xe, (133)Xe and (135)Xe, we took the opportunity to test these setups for the measurement of a (127)Xe standard. The results and a detailed description of these measurements are presented in this paper. They illustrate the complexity of (127)Xe decay, emitting simultaneously several ?, X-rays, conversion electrons and Auger electrons; this results in highly summated coincidence spectra. The measurements performed provide precise electron energy calibration of the setups. The count rate of electrons in coincidence with iodine K? X-rays was found to be surprisingly low, leading to the study of electron-gated photon spectrum. Finally, a comparison of three photon/electron coincidence spectra obtained with three different setups is given. The use of (127)Xe as a standard for energy calibration of IMS noble gas station is possible, but it appears to be quite complicated for efficiency check of noble gas station equipped with ?/? detectors. PMID:24657473

Cagniant, A; Le Petit, G; Nadalut, B; Gross, P; Richard-Bressand, H; Fontaine, J-P; Douysset, G

2014-07-01

58

Evaluation of Quality-Assurance/Quality-Control Data Collected by the U.S. Geological Survey from Wells and Springs between the Southern Boundary of the Idaho National Engineering and Environmental Laboratory and the Hagerman Area, Idaho, 1989 through 1995  

SciTech Connect

The U.S. Geological (USGS) and the Idaho Department of Water Resources, in cooperation with the U.S. Department of Energy, collected and analyzed water samples to monitor the water quality of the Snake River Plain aquifer from the southern boundary of the Idaho National Engineering and Environmental Laboratory to the Hagerman area, Idaho. Concurrently, replicate samples and blank samples were collected and analyzed as part of the quality-assurance/quality-control program. Samples were analyzed from inorganic constituents, gross radioactivity and radionuclides, organic constituents, and stable isotopes. To evaluate the precision of field and laboratory methods, analytical results of the water-quality and replicate samples were compared statistically for equivalence on the basis of the precision associated with each result. Statistical comparisons of the data indicated that 95 percent of the results of the replicate pairs were equivalent. Blank-sample analytical results indicated th at the inorganic blank water and volatile organic compound blank water from the USGS National Water Quality Laboratory and the distilled water from the Idaho Department of Water Resources were suitable for blanks; blank water from other sources was not. Equipment-blank analytical results were evaluated to determine if a bias had been introduced and possible sources of bias. Most equipment blanks were analyzed for trace elements and volatile organic compounds; chloroform was found in one equipment blank. Two of the equipment blanks were prepared after collection and analyses of the water-quality samples to determine whether contamination had been introduced during the sampling process. Results of one blank indicated that a hose used to divert water away from pumps and electrical equipment had contaminated the samples with some volatile organic compounds. Results of the other equipment blank, from the apparatus used to filter dissolved organic carbon samples, indicated that the filtering apparatus did not affect water-quality samples.

Williams, L.M.; Bartholomay, R.C.; Campbell, L.J.

1998-10-01

59

Perspectives on quality control, risk management, and analytical quality management.  

PubMed

Quality control (QC) practices are changing in US laboratories as Centers for Medicare and Medicaid Services adopts individualized QC plans as a new option for compliance with the Clinical Laboratory Improvement Amendments regulations. The Joint Commission provides general guidance for applying risk management in health care organizations. The EP23A (Evaluation Protocol 23A) document from the Clinical and Laboratory Standards Institute provides specific guidance on the use of risk management for developing analytical QC plans. Medical laboratories should integrate risk management tools with existing quality management techniques and activities to provide an overall plan for analytical quality management. PMID:23331725

Westgard, James O

2013-03-01

60

Randomized trial interpreting sputum quality in a clinical laboratory.  

PubMed Central

The role for laboratory interpretation of microbiologic results remains controversial, and many laboratories leave the interpretation of culture results entirely to physicians. We examined the effects of furnishing a laboratory interpretation of sputum quality on physician decision making. Quality of sputum was determined on Gram-stained smears by using a modification of the criteria of Bartlett (R. C. Bartlett, Medical Microbiology: Quality, Cost, and Clinical Relevance, p. 24-31, 1974). A total of 301 poor-quality specimens were randomized either to receive written interpretation of Gram stain results or to a control group for which Gram stain results were reported without interpretation. Physicians were more likely to follow up a poor-quality specimen with a second specimen if they had been furnished an interpretation of the results from the original Gram stain (22 versus 12%; P = 0.025). We conclude that laboratory-based interpretation of microbiologic results can improve physician decision making.

Mizrachi, H H; Valenstein, P N

1987-01-01

61

Helping You Identify Quality Laboratory Services  

MedlinePLUS

... if you have questions? Quality oversight ? Is the laboratory accredited by a nationally recognized accrediting body such as The Joint Commission? Joint Commission accreditation means the organization voluntarily sought accreditation and met ...

62

[Guidelines for quality management of laboratory information systems].  

PubMed

After a short presentation of the SFIL, this article presents the working parties initiated by the SFIL. At the end of each of these works were published texts, recommendations and tools for the biologists and vendors, in order that the laboratory information system becomes a component of medical laboratory quality. Recommendations for quality control of information systems, resulting from these documents, are presented. PMID:23765024

Otter, M; Domas, G

2013-06-01

63

QUALITY CONTROL - VARIABILITY IN PROTOCOLS  

EPA Science Inventory

The EPA Risk Reduction Engineering Laboratory?s Quality Assurance Office, which published the popular pocket guide Preparing Perfect Project Plans, is now introducing another quality assurance reference aid. The document Variability in Protocols (VIP) was initially designed as a ...

64

Multivariate Quality Control Procedures.  

National Technical Information Service (NTIS)

This report presents the design procedures and average run lengths of two multivariate cumulative sum (CUSUM) quality control procedures. The first CUSUM procedure reduces each multivariate observation to a scaler and then forms a CUSUM of the scalers. Th...

R. B. Crosier

1988-01-01

65

Bias from two analytical laboratories involved in a long-term air monitoring program measuring organic pollutants in the Arctic: a quality assurance/quality control assessment.  

PubMed

Initiated in 1992, air monitoring of organic pollutants in the Canadian Arctic provided spatial and temporal trends in support of Canada's participation in the Stockholm Convention of Persistent Organic Pollutants. The specific analytical laboratory charged with this task was changed in 2002 while field sampling protocols remained unchanged. Three rounds of intensive comparison studies were conducted in 2004, 2005, and 2008 to assess data comparability between the two laboratories. Analysis was compared for organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs) and polycyclic aromatic hydrocarbons (PAHs) in standards, blind samples of mixed standards and extracts of real air samples. Good measurement accuracy was achieved for both laboratories when standards were analyzed. Variation of measurement accuracy over time was found for some OCPs and PCBs in standards on a random and non-systematic manner. Relatively low accuracy in analyzing blind samples was likely related to the process of sample purification. Inter-laboratory measurement differences for standards (<30%) and samples (<70%) were generally less than or comparable to those reported in a previous inter-laboratory study with 21 participating laboratories. Regression analysis showed inconsistent data comparability between the two laboratories during the initial stages of the study. These inter-laboratory differences can complicate abilities to discern long-term trends of pollutants in a given sampling site. It is advisable to maintain long-term measurements with minimal changes in sample analysis. PMID:21997219

Su, Yushan; Hung, Hayley; Stern, Gary; Sverko, Ed; Lao, Randy; Barresi, Enzo; Rosenberg, Bruno; Fellin, Phil; Li, Henrik; Xiao, Hang

2011-11-01

66

222-S Laboratory Quality Assurance Plan. Revision 1  

SciTech Connect

This Quality Assurance Plan provides,quality assurance (QA) guidance, regulatory QA requirements (e.g., 10 CFR 830.120), and quality control (QC) specifications for analytical service. This document follows the U.S Department of Energy (DOE) issued Hanford Analytical Services Quality Assurance Plan (HASQAP). In addition, this document meets the objectives of the Quality Assurance Program provided in the WHC-CM-4-2, Section 2.1. Quality assurance elements required in the Guidelines and Specifications for Preparing Quality Assurance Program Plans (QAMS-004) and Interim Guidelines and Specifications for Preparing Quality Assurance Project Plans (QAMS-005) from the US Environmental Protection Agency (EPA) are covered throughout this document. A quality assurance index is provided in the Appendix A. This document also provides and/or identifies the procedural information that governs laboratory operations. The personnel of the 222-S Laboratory and the Standards Laboratory including managers, analysts, QA/QC staff, auditors, and support staff shall use this document as guidance and instructions for their operational and quality assurance activities. Other organizations that conduct activities described in this document for the 222-S Laboratory shall follow this QA/QC document.

Meznarich, H.K.

1995-07-31

67

The andrology laboratory in an Assisted Reproductive Technologies program. Quality assurance and laboratory methodology.  

PubMed

Assuring the highest possible quality of care to the patient is the first goal of the andrology laboratory. Quality control and quality assurance as they apply to the andrology laboratory are outlined, and special problems in quality control for sperm function assays are addressed. An example of the patient review process is presented. Quality of care also depends on the ability of the laboratory to perform appropriate tests of sperm function that can diagnose sperm defects, predict success or failure of in vitro fertilization, and lead to rational therapies for sperm dysfunctions. Methods for, and diagnostic value of, sperm swim-out, enhanced sperm penetration assays, acrosome reaction assessment, motility analysis of capacitating sperm, and sperm-zona binding assays are reviewed. No single test, other than in vitro fertilization itself, is capable of providing a complete diagnosis or a highly accurate prediction. A battery of sperm function tests, arranged in an algorithm, is presented as a theoretically better approach. PMID:1429216

Muller, C H

1992-01-01

68

RCL - Remotely Controlled Laboratories  

NSDL National Science Digital Library

The purpose of this web site is to provide Remote Controlled Labs (RCLs) to users on the internet. These are real experiments which can be executed by a client using a standard web browser interacting with a web server controlling the experiment. Web cams allow the user to observe the on-going experiment. The experiments are designed to encourage interactive exploration by students and emphasize the importance of experiments in physics. The labs available include Millikan's oil-drop experiment, Rutherford scattering, the speed of light, the photoelectric effect, I-V characteristics, radioactivity, and control of robots.

2009-02-07

69

Software Quality-Control Program,  

National Technical Information Service (NTIS)

The overall standards of the program stipulate policies and procedures for implementing economical yet efficient software quality control. The program is designed for quality-control organization and policy control as well as quality assurance and mainten...

I. Nakane H. Kobayashi T. Tsuchiya M. Masuda

1988-01-01

70

CHAPTER 2 QUALITY ASSURANCE AND QUALITY CONTROL IN RESEARCH DEVELOPMENT  

Microsoft Academic Search

It is now internationally recognised that for any laboratory to produce reliable data it must implement an appropriate programme of quality assurance procedures. It must, as a minimum a. ensure it is using methods which have been validated as fit for the purpose before use by the laboratory. These methods should be fully documented, staff should be trained and control

Peter Bode

71

LABCON - Laboratory Job Control program  

NASA Technical Reports Server (NTRS)

Computer program LABCON controls the budget system in a component test laboratory whose workload is made up from many individual budget allocations. A common denominator is applied to an incoming job, to which all effort is charged and accounted for.

Reams, L. T.

1969-01-01

72

Computer control of check laboratories  

Microsoft Academic Search

By control of technical or organizational-technical objects is meant the introduction of corrections into their operating regimes and procedures on the basis of the information obtained and processed concerning these objects. Control of the work of a check laboratory presupposes, in particular, the periodic introduction of corrections into the solution of such problems as the selection of the optimal number

L. N. Zakashanskii; L. A. Lubochkov; D. I. Maiorov

1971-01-01

73

Iowa Central Quality Fuel Testing Laboratory  

SciTech Connect

The objective of this project is to finalize the creation of an independent quality fuel testing laboratory on the campus of Iowa Central Community College in Fort Dodge, Iowa that shall provide the exploding biofuels industry a timely and cost-effective centrally located laboratory to complete all state and federal fuel and related tests that are required. The recipient shall work with various state regulatory agencies, biofuel companies and state and national industry associations to ensure that training and testing needs of their members and American consumers are met. The recipient shall work with the Iowa Department of Ag and Land Stewardship on the development of an Iowa Biofuel Quality Standard along with the Development of a standard that can be used throughout industry.

Heach, Don; Bidieman, Julaine

2013-09-30

74

External quality assessment of Jordanian clinical chemistry laboratories.  

PubMed

A two-year study using inter-laboratory surveys has been carried out to assess the analytical quality of Jordanian clinical chemistry laboratories. The study surveyed greater than 65% (60 laboratories) of Jordanian laboratories using 18 control specimens and covering a total of 15 analytes. Close agreement was obtained between the consensus values and the designated values for analytes which had mean values within the normal range, whereas significantly lower consensus values were obtained for glucose, creatinine, bilirubin and urea in the pathological range. Considerable interlaboratory variation was observed in Jordan relative to EQA schemes in other countries. This study highlighted several problems in Jordanian laboratories, and stressed the need for a national EQA scheme with an effective means of providing continuous advice, education and training in clinical chemistry. PMID:1610107

Bilto, Y Y

1992-05-01

75

Quality control of seasonal influenza vaccines.  

PubMed

The purpose of seasonal influenza vaccination is to prevent its spread. The vaccines contain strains of the influenza virus recommended and approved for a particular season. Just like any other medicinal product, all vaccines require marketing approval. Batches of approved vaccines are extensively tested by the manufacturers and additionally controlled by the approving authorities, which issue the quality control certificates. This article not only to describes the legal background of quality control, but also how control test results obtained by a Croatian official control laboratory are compared to manufacturer's results. We have found that testing results can slightly differ depending on methods/analytical procedures used in different laboratories. This investigation has also shown how important it is to test finished medicinal products, independently of testing at intermediate stages, and how retesting by control authorities ensures that marketed vaccines meet quality standards. PMID:21183435

Manduši? Nazor, Tamara; Pipi? Kosanovi?, Marta; Tomi?, Siniša

2010-12-01

76

Quality control measures for SMP environmental sensors  

NASA Astrophysics Data System (ADS)

Research and development efforts at Cornerstone Research Group Inc. (CRG) have led to commercialization efforts on several projects where shape memory polymer (SMP) materials are being transitioned from laboratory development to manufacturing and production. During this process, quality-control efforts are of vital importance for successfully implementing smart materials technologies in commercial applications. Here, CRG reports quality-control procedures being developed for mass production of environmental exposure sensors. These measures include chemical analysis procedures for insuring resin quality at the front-end of the production line as well as back-end quality-assurance tests for production validation on the SMP product.

Rauscher, Michael D.; Tebalt, Thomas H.; Klein, Andrew K.; Havens, Teresa; Everhart, Joel; McFerran, Jace

2009-03-01

77

Quality assurance program for field health laboratories  

SciTech Connect

The Federal Mine Safety and Health Act of 1977 (and previously the Federal Coal Mine Health and Safety Act of 1969) established mandatory dust standards for coal mines. Title II requires the Secretary of Labor to make frequent inspections of coal mines to determine compliance with the mandated 2.0 mg/m/sup 3/ respirable dust standard. Such inspections are made by representatives of the Secretary, who are coal mine inspectors of the Mine Safety and Health Administration (MSHA). Sampling equipment used to assess respirable dust concentrations is calibrated and maintained at local field laboratories located in each Coal Mine Safety and Health district. Samples collected during inspections are weighed and analyzed at these laboratories. A selected number of laboratories are also qualified to weigh operator samples in accordance with provisions promulgated in Title 30, Code of Federal Regulations, Part 70. This paper describes the quality assurance program conducted to assure the performance integrity of the field laboratories in the maintenance and calibration of respirable dust sampling equipment and the weighing of respirable coal mine dust samples. 18 figs.

Treaftis, H.N.; Parobeck, P.S.

1984-01-01

78

Quality control: Variability in protocols  

SciTech Connect

The document Variability in Protocols (VIP) was initially designed as a quick reference for personnel performing QA audits, but it also has found its place in serving as a reference source for laboratory managers as well as personnel reviewing or developing QA Project Plans. Variability in Protocols contains tabular summaries of the quality control differences and similarities for some of the most frequently used analytical methods for water, soils, and other environmental samples. The document has been prepared in an attempt to bring together the separate methods that became a product of the major environmental statutes. Noticeable differences between methods are evidenced in method detection limits, calibration methods, blanks, spikes, and several other parameters included in the summary. The tabular format provides quick and easy access to important, needed information. VIP can provide guidance when preparing Quality Assurance Project Plans. Managers, field sampling team members, auditors, and laboratory personnel alike will find the document helpful in determining the most suitable method of chemical analysis for their various purposes.

Simes, G.Y.

1991-09-01

79

CONTROLLING THE QUALITY OF TRAINING.  

ERIC Educational Resources Information Center

THE NEED FOR A QUALITY CONTROL SYSTEM IN A MILITARY TRAINING PROGRAM AND THE METHODS OF ESTABLISHING SUCH A UNIT ARE DESCRIBED AND EVALUATED IN THIS REPORT. THE PURPOSE OF QUALITY CONTROL IS TO INSURE A SATISFACTORY STANDARD OF COMPETENCE AMONG THE STUDENTS WHO GRADUATE, TO MAINTAIN THIS QUALITY BY A CONTINUOUS MONITORING PROCESS, AND TO IMPROVE…

SMITH, ROBERT G., JR.

80

Quality control on the frontier  

PubMed Central

In the world of high-throughput sequencing there are numerous challenges to effective data quality control. There are no single quality metrics which are appropriate in all conditions. Here we detail the different open source software used at the Exeter Sequencing Service to provide generic quality control information, as well as more specific metrics for genomic and transcriptomic libraries run on Illumina platforms.

Paszkiewicz, Konrad H.; Farbos, Audrey; O'Neill, Paul; Moore, Karen

2014-01-01

81

Evaluation of Quality-Assurance\\/Quality-Control Data Collected by the U.S. Geological Survey from Wells and Springs between the Southern Boundary of the Idaho National Engineering and Environmental Laboratory and the Hagerman Area, Idaho, 1989 through 1995  

Microsoft Academic Search

The U.S. Geological (USGS) and the Idaho Department of Water Resources, in cooperation with the U.S. Department of Energy, collected and analyzed water samples to monitor the water quality of the Snake River Plain aquifer from the southern boundary of the Idaho National Engineering and Environmental Laboratory to the Hagerman area, Idaho. Concurrently, replicate samples and blank samples were collected

L. M. Williams; R. C. Bartholomay; L. J. Campbell

1998-01-01

82

Reducing Communication Delays and Improving Quality of Care with a Tuberculosis Laboratory Information System in Resource Poor Environments: A Cluster Randomized Controlled Trial  

PubMed Central

Background Lost, delayed or incorrect laboratory results are associated with delays in initiating treatment. Delays in treatment for Multi-Drug Resistant Tuberculosis (MDR-TB) can worsen patient outcomes and increase transmission. The objective of this study was to evaluate the impact of a laboratory information system in reducing delays and the time for MDR-TB patients to culture convert (stop transmitting). Methods Setting: 78 primary Health Centers (HCs) in Lima, Peru. Participants lived within the catchment area of participating HCs and had at least one MDR-TB risk factor. The study design was a cluster randomized controlled trial with baseline data. The intervention was the e-Chasqui web-based laboratory information system. Main outcome measures were: times to communicate a result; to start or change a patient's treatment; and for that patient to culture convert. Results 1671 patients were enrolled. Intervention HCs took significantly less time to receive drug susceptibility test (DST) (median 11 vs. 17 days, Hazard Ratio 0.67 [0.62–0.72]) and culture (5 vs. 8 days, 0.68 [0.65–0.72]) results. The time to treatment was not significantly different, but patients in intervention HCs took 16 days (20%) less time to culture convert (p?=?0.047). Conclusions The eChasqui system reduced the time to communicate results between laboratories and HCs and time to culture conversion. It is now used in over 259 HCs covering 4.1 million people. This is the first randomized controlled trial of a laboratory information system in a developing country for any disease and the only study worldwide to show clinical impact of such a system. Trial Registration ClinicalTrials.gov NCT01201941

Blaya, Joaquin A.; Shin, Sonya S.; Yagui, Martin; Contreras, Carmen; Cegielski, Peter; Yale, Gloria; Suarez, Carmen; Asencios, Luis; Bayona, Jaime; Kim, Jihoon; Fraser, Hamish S. F.

2014-01-01

83

SIMBAD quality-control  

NASA Technical Reports Server (NTRS)

The astronomical database SIMBAD developed at the Centre de donnees astronomiques de Strasbourg presently contains 760,000 objects (stellar and non-stellar). It has the unique characteristic of being structured specifically for astronomical objects. All types of heterogeneous data (bibliographic references, measurements, and sets of identification) are connected with each object. The attributes that define quality of the database include the following. Reliability: cross-identification should not rely upon just exact values object coordinates. It also means that information attached to one simple object should be consistent. The existing data must be controlled in order to start with a reliable base and to cross-identify new data assuring the quality as data grows. Exhaustivity: delays between publication of new informations and their inclusion in the database should be as short as possible. The integrity of the database has to be maintained as data accumulates. Taking the amount of data into consideration and the rate of new data production, it is necessary to use automatic methods. One of the possibilities is to use multivariate data analysis. The factor-space is a n-dimensional relevancy space which is described by the n-axes representing a set of n subject matter headings; the words and phrases can be used to scale the axes and the documents are then a vector average of the terms within them. The application reported herein is based on the NASA-STI bibliographical database. The selected data concern astronomy, astrophysics, and space radiation (102,963 references from 1975 to 1991 included 8070 keywords). The F-space is built from this bibliographical data. By comparing the F-space position obtained from the NASA-STI keywords with the F-space position obtained from the SIMBAD references, the authors will be able to show whether it is possible to retrieve information with a restricted set of words only. If the comparison is valid, this will be a way to enter bibliographic information in the SIMBAD quality control process. Furthermore, it is possible to connect the physical measurements of stars from SIMBAD to literature concerning these stars from the NASA-STI abstracts. The physical properties of stars (e.g. UBV colors) are not randomly distributed. Stars are distributed among different clusters in a physical parameter space. The authors will show that there are some relations between this classification and the literature concerning these objects clusters in a factor space. They will investigate the nature of the relationship between the SIMBAD measurements and the bibliography. These would be new relationships that are not pre-established by an astronomer. In addition, the bibliography could be neutral information that can be used in combination with the measured parameters.

Lesteven, Soizick

1992-01-01

84

Cost Effectiveness of Adopted Quality Requirements in Hospital Laboratories  

PubMed Central

Background The present study was designed in quasi-experiment to assess adoption of the essential clauses of particular clinical laboratory quality management requirements based on international organization for standardization (ISO 15189) in hospital laboratories and to evaluate the cost effectiveness of compliance to ISO 15189. Methods: The quality management intervention based on ISO 15189 was conceded through three phases; pre – intervention phase, Intervention phase and Post-intervention phase. Results: In pre-intervention phase the compliance to ISO 15189 was 49% for study group vs. 47% for control group with P value 0.48, while the post intervention results displayed 54% vs. 79% for study group and control group respectively in compliance to ISO 15189 and statistically significant difference (P value 0.00) with effect size (Cohen’s d) of (0.00) in pre-intervention phase and (0.99) in post – intervention phase. The annual average cost per-test for the study group and control group was 1.80 ± 0.25 vs. 1.97 ± 0.39, respectively with P value 0.39 whereas the post-intervention results showed that the annual average total costs per-test for study group and control group was 1.57 ± 0.23 vs 2.08 ± 0.38, P value 0.019 respectively, with cost-effectiveness ratio of (0.88) in pre -intervention phase and (0.52) in post-intervention phase. Conclusion: The planned adoption of quality management requirements (QMS) in clinical laboratories had great effect to increase the compliance percent with quality management system requirement, raise the average total cost effectiveness, and improve the analytical process capability of the testing procedure.

HAMZA, Alneil; AHMED-ABAKUR, Eltayib; ABUGROUN, Elsir; BAKHIT, Siham; HOLI, Mohamed

2013-01-01

85

Method of Analysis by the U.S. Geological Survey California District Sacramento Laboratory?Determination of Trihalomethane Formation Potential, Method Validation, and Quality-Control Practices  

USGS Publications Warehouse

An analytical method for the determination of the trihalomethane formation potential of water samples has been developed. The trihalomethane formation potential is measured by dosing samples with chlorine under specified conditions of pH, temperature, incubation time, darkness, and residual-free chlorine, and then analyzing the resulting trihalomethanes by purge and trap/gas chromatography equipped with an electron capture detector. Detailed explanations of the method and quality-control practices are provided. Method validation experiments showed that the trihalomethane formation potential varies as a function of time between sample collection and analysis, residual-free chlorine concentration, method of sample dilution, and the concentration of bromide in the sample.

Crepeau, Kathryn L.; Fram, Miranda S.; Bush, Noel

2004-01-01

86

QUALITY ASSURANCE IN RESEARCH LABORATORIES: RULES AND REASON  

EPA Science Inventory

Quality Assurance in Research Laboratories: Rules and Reason Ron Rogers, Quality Assurance and Records Manager, Environmental Carcinogenesis Division, NHEERL/ORD/US EPA, Research Triangle Park, NC, 27709 To anyone who has actively participated in research, as I have...

87

Computer-assisted quality control in clinical chemistry.  

PubMed

A MUMPS comuter program, which stores and retrieves quality-control data from all automated and manual work-station in the laboratory, has been developed as part of a laboratory information system. Tabular displays, Levey-Jennings charts, and summary statistics are available on a real-time basis. Significant economy over previous manual methods has been observed, and the total quality-control program in the laboratory has become a more active and timely process. PMID:852109

Sher, P P

1977-05-01

88

Method of analysis at the U.S. Geological Survey California Water Science Center, Sacramento Laboratory - determination of haloacetic acid formation potential, method validation, and quality-control practices  

USGS Publications Warehouse

An analytical method for the determination of haloacetic acid formation potential of water samples has been developed by the U.S. Geological Survey California Water Science Center Sacramento Laboratory. The haloacetic acid formation potential is measured by dosing water samples with chlorine under specified conditions of pH, temperature, incubation time, darkness, and residual-free chlorine. The haloacetic acids formed are bromochloroacetic acid, bromodichloroacetic acid, dibromochloroacetic acid, dibromoacetic acid, dichloroacetic acid, monobromoacetic acid, monochloroacetic acid, tribromoacetic acid, and trichloroacetic acid. They are extracted, methylated, and then analyzed using a gas chromatograph equipped with an electron capture detector. Method validation experiments were performed to determine the method accuracy, precision, and detection limit for each of the compounds. Method detection limits for these nine haloacetic acids ranged from 0.11 to 0.45 microgram per liter. Quality-control practices include the use of blanks, quality-control samples, calibration verification standards, surrogate recovery, internal standard, matrix spikes, and duplicates.

Zazzi, Barbara C.; Crepeau, Kathryn L.; Fram, Miranda S.; Bergamaschi, Brian A.

2005-01-01

89

Multivariate approach to quality control in clinical chemistry  

Microsoft Academic Search

When monitoring analyzer performance in the clinical setting, laboratories are required to test multiple con- centrations of control material on a daily basis. Because of the nature of laboratory testing, there is the potential for correlation between the concentrations of control material being monitored. Although traditional clinical quality-control approaches make an underlying as- sumption of independence with respect to the

Jerry Dechert; Kenneth E. Case

1998-01-01

90

Disk diffusion testing, quality control guidelines, and antimicrobial spectrum of HR810, a fourth-generation cephalosporin, in clinical microbiology laboratories.  

PubMed Central

HR810 is a new, very broad-spectrum cephalosporin with significant activity against members of the family Enterobacteriaceae, pseudomonads, gram-positive cocci, and anaerobes that is generally greater than the third-generation cephalosporins (99.6% of 4,128 clinical facultative enteric isolates were inhibited by less than or equal to 8.0 micrograms of HR810 per ml). Tests and statistical methods to establish in vitro antimicrobial susceptibility test criteria favor tentative breakpoints of greater than or equal to 18 mm (less than or equal to 8.0 micrograms/ml) as susceptible and less than or equal to 14 mm (greater than or equal to 32 micrograms/ml) as resistant. This provides a 93.7 to 98.3% absolute interpretive accuracy. Several preliminary ranges for zone sizes obtained with quality control organisms are proposed for the 30-micrograms HR810 disk diffusion test used during the clinical trials.

Jones, R N; Thornsberry, C; Barry, A L; Ayers, L; Brown, S; Daniel, J; Fuchs, P C; Gavan, T L; Gerlach, E H; Matsen, J M

1984-01-01

91

Principles and Practices for Quality Assurance and Quality Control  

USGS Publications Warehouse

Quality assurance and quality control are vital parts of highway runoff water-quality monitoring projects. To be effective, project quality assurance must address all aspects of the project, including project management responsibilities and resources, data quality objectives, sampling and analysis plans, data-collection protocols, data quality-control plans, data-assessment procedures and requirements, and project outputs. Quality control ensures that the data quality objectives are achieved as planned. The historical development and current state of the art of quality assurance and quality control concepts described in this report can be applied to evaluation of data from prior projects.

Jones, Berwyn E.

1999-01-01

92

Method of Analysis by the U.S. Geological Survey California District Sacramento Laboratory-- Determination of Dissolved Organic Carbon in Water by High Temperature Catalytic Oxidation, Method Validation, and Quality-Control Practices  

USGS Publications Warehouse

An analytical method has been developed for the determination of dissolved organic carbon concentration in water samples. This method includes the results of the tests used to validate the method and the quality-control practices used for dissolved organic carbon analysis. Prior to analysis, water samples are filtered to remove suspended particulate matter. A Shimadzu TOC-5000A Total Organic Carbon Analyzer in the nonpurgeable organic carbon mode is used to analyze the samples by high temperature catalytic oxidation. The analysis usually is completed within 48 hours of sample collection. The laboratory reporting level is 0.22 milligrams per liter.

Bird, Susan M.; Fram, Miranda S.; Crepeau, Kathryn L.

2003-01-01

93

Quality Control of Meteorological Observations.  

National Technical Information Service (NTIS)

Quality control of meteorological observations Is an Integral part of atmospheric analysis and prediction, since erroneous observations can adversely impact the accuracy of these environmental products. The meteorological observations are subjected to var...

N. L Baker

1992-01-01

94

Quality control during carotid endarterectomy.  

PubMed

Although some form of quality control assessment is standard practice following virtually all forms of peripheral vascular reconstruction, it is seldom applied to carotid endarterectomy. This is despite the fact that the complications following endarterectomy can be catastrophic, are often related to technical error and are not easily remedied. A number of novel quality control techniques are now available. This review article summarizes the application of these methods to ensuring optimal surgical practice in patients undergoing carotid endarterectomy. PMID:9546926

Naylor, A R; Gaunt, M E

1996-01-01

95

[Quality control in herbal supplements].  

PubMed

Quality and safety of food and herbal supplements are the result of a whole of different elements as good manufacturing practice and process control. The process control must be active and able to individuate and correct all possible hazards. The main and most utilized instrument is the hazard analysis critical control point (HACCP) system the correct application of which can guarantee the safety of the product. Herbal supplements need, in addition to standard quality control, a set of checks to assure the harmlessness and safety of the plants used. PMID:16037649

Oelker, Luisa

2005-01-01

96

[The external evaluation of study quality: the role in maintaining the reliability of laboratory information].  

PubMed

The external evaluation of quality of clinical laboratory examinations was gradually introduced in USSR medical laboratories since 1970s. In Russia, in the middle of 1990 a unified all-national system of external evaluation quality was organized known as the Federal center of external evaluation of quality at the basis of laboratory of the state research center of preventive medicine. The main positions of policy in this area were neatly formulated in the guidance documents of ministry of Health. Nowadays, the center of external evaluation of quality proposes 100 and more types of control studies and permanently extends their specter starting from interests of different disciplines of clinical medicine. The consistent participation of laboratories in the cycles of external evaluation of quality intrinsically promotes improvement of indicators of properness and precision of analysis results and increases reliability of laboratory information. However, a significant percentage of laboratories does not participate at all in external evaluation of quality or takes part in control process irregularly and in limited number of tests. The managers of a number of medical organizations disregard the application of the proposed possibilities to increase reliability of laboratory information and limit financing of studies in the field of quality control. The article proposes to adopt the national standard on the basis of ISO 17043 "Evaluation of compliance. The common requirements of professional competence testing". PMID:24340751

Men'shikov, V V

2013-08-01

97

Clay-liner construction and quality control  

Microsoft Academic Search

Soil handling and liner-construction practices at hazardous-waste-management facilities are documented. Soil characterizations, processing techniques, construction methods, and quality control of constructed liners are reviewed and compared. Results indicate widely different testing and construction methods at 23 facilities nationwide. Laboratory research indicates that selected clay soils exhibit low hydraulic conductivity to water and certain non-water liquid wastes. This characteristic makes clay

J. Jeffrey Peirce; Goran Sallfors; Eric Peterson

1986-01-01

98

Integrated Electromechanical Controls Laboratory using Programmable Logic Controllers  

Microsoft Academic Search

The energy conversion laboratory at Christian Brothers University was reorganized in the summer of 1992 in an effort to design and build a new integrated electomechanical controls laboratory. The laboratory is a multidimentional facility in a sense that it will allow the students from three engineering disciplines, chemical, electical and mechanical to run experiments in linear controls, energy conversion, digital

J. E. Beaini; L. Althaus; J. C. Olabe; E. Welch

1993-01-01

99

Development of Suspended Solids Quality Control and Performance Evaluation Samples.  

National Technical Information Service (NTIS)

A two phase study was conducted to develop a synthetic suspended solids sample for use as quality control check and performance evaluation within environmental monitoring laboratories. The first phase consisted of a feasibility study to determine compound...

E. L. Stover P. J. Marks

1976-01-01

100

Quality assurance plan for the Close Support Laboratory for the remedial investigation at Oak Ridge National Laboratory, Oak Ridge, Tennessee  

SciTech Connect

The primary purpose of the Close Support Laboratory (CSL) is to provide rapid radiological screening of investigation-derived samples before they are shipped to off-site laboratories for more detailed analyses. Analyses for volatile organic compounds and miscellaneous water quality parameters are also performed at the CSL. CSL data are also used to select samples for off-site laboratory analysis, for rapid qualitative and quantitative determinations, and for other processes when off-site analysis is not needed and/or is impractical. This plan specifies methods of implementing analytical and radiological protocols and procedures for the documentation, handling, control, and analysis of samples and describes the levels of authority and responsibility for laboratory operation. Specific quality control methods used by the CSL for individual analyses are described in project procedures.

Not Available

1993-08-01

101

Coal Quality Control with Control Charts  

Microsoft Academic Search

Coal properties are inherently variable even within a single coal seam due to reasons such as coalification history and mining method. Since nonconsistent coal characteristics negatively affect the efficiency and production cost of power plants as well as the profitability of the coal producer, special attention should be paid to control the variability of coal quality. In this paper, variations

S. Elevli

2006-01-01

102

A quality manual for the clinical laboratory including the elements of a quality system. Proposed guidelines.  

PubMed

Development of quality manuals is a means for the promotion of quality in clinical laboratories by describing the total quality system. It also provides opportunity of checking whether the quality system is implemented in reality and demonstrates to the hospital administration and the clinicians that the laboratory is committed to quality. The intention of these guidelines is to describe the elements of the quality system for a large clinical laboratory, and to present such a system in the form of a quality manual. The proposed guidelines comply, where relevant, with ISO/IEC guide 25 'General requirements for the technical competence of testing laboratories' and EN 45001 'General criteria for the operation of testing laboratories'. The document may be used as an aid for laboratories wishing to be accredited according to EN 45001, or intending to apply for formal certification of their quality systems, according to ISO 9001 'Quality systems--Model for quality assurance in design/development, production, installation, and servicing' utilizing ISO 9004 'Quality management and quality system elements--guidelines; Part 2 Guidelines for service'. However, information about the minimum requirements for official recognition should be obtained from the particular accreditation or certification body concerned. PMID:8465158

Dybkaer, R; Jordal, R; Jørgensen, P J; Hansson, P; Hjelm, M; Kaihola, H L; Kallner, A; Rustad, P; Uldall, A; de Verdier, C H

1993-01-01

103

Built-Up Roof Construction Quality Control.  

National Technical Information Service (NTIS)

This report recommends ways to improve the performance of built-up roofing in Army facilities by advancing roof construction quality control and quality assurance. This study assessed the state of the art in roofing quality control; evaluated existing Arm...

E. S. Lindow E. Marvin M. J. Rosenfield J. Blair

1979-01-01

104

Bivariate dispersion quality control charts  

Microsoft Academic Search

A Shewhart procedure is used to simultaneously control the standard deviations of quality characteristics assumed to have a bivariate normal distribution. Following Krishnaiah et al (1963), we use the bivariate chi-square distribution to determine probabilities of out-of-control signals and thus the respective average run lengths (ARLs). Results from an example indicate that for both one-sided and two-sided cases, signals occur

Kwami Tuprah; William H. Woodall

1986-01-01

105

Quality control in molecular immunohistochemistry  

PubMed Central

Immunoperoxidase histochemistry is a widespread method of assessing expression of biomolecules in tissue samples. Accurate assessment of the expression levels of genes is critical for the management of disease, particularly as therapy targeted to specific molecules becomes more widespread. Determining the quality of preservation of macromolecules in tissue is important to avoid false negative and false positive results. In this review we discuss (1) issues of sensitivity (false negativity) and specificity (false positivity) of immunohistochemical stains, (2) approaches to better understanding differences in immunostains done by different laboratories (including the recently proposed MISFISHIE specification for tissue localization studies), and (3) approaches to assessing the quality of preservation of macromolecules in tissue, particularly in small biopsy samples.

2008-01-01

106

Data Acquisition and Control Systems Laboratory  

NASA Technical Reports Server (NTRS)

The Data Acquisition and Control Systems (DACS) Laboratory is a facility at Stennis Space Center that provides an off test-stand capability to develop data-acquisition and control systems for rocket-engine test stands. It is also used to train new employees in state-of-the-art systems, and provides a controlled environment for troubleshooting existing systems, as well as the ability to evaluate the application of new technologies and process improvements. With the SSC propulsion testing schedules, without the DACS Laboratory, it would have been necessary to perform most of the development work on actual test systems, thereby subjecting both the rocket-engine testing and development programs to substantial interference in the form of delays, restrictions on modifications of equipment, and potentially compromising software configuration control. The DACS Laboratory contains a versatile assortment of computer hardware and software, digital and analog electronic control and data-acquisition equipment, and standard electronic bench test equipment and tools. Recently completed Control System development and software verification projects include support to the joint NASA/Air Force Integrated Powerhead Demonstration (IPD) LOX & LH2 PreBurner and Turbopump ground testing programs. In other recent activities, the DACS Laboratory equipment and expertise have supported the off-stand operation of high-pressure control valves to correct valve leak problems prior to installation on the test stand. Future plans include expanding the Laboratory's capabilities to provide cryogenic control valve characterization prior to installation, thereby reducing test stand activation time.

Holland, Randy; Jensen, Scott; Burrel, Terrence; Spooner, Richard

2002-01-01

107

New laboratory tools in the assessment of bone quality  

Microsoft Academic Search

Bone quality is a complex set of intricated and interdependent factors that influence bone strength. A number of methods have\\u000a emerged to measure bone quality, taking into account the organic or the mineral phase of the bone matrix, in the laboratory.\\u000a Bone quality is a complex set of different factors that are interdependent. The bone matrix organization can be described

D. Chappard; M. F. Baslé; E. Legrand; M. Audran

2011-01-01

108

Quality Assurance/Quality Control Jobs  

NASA Astrophysics Data System (ADS)

The production of a quality and safe food product is essential to the success of any food manufacturing facility. Because of this great importance, a career in quality can be extremely rewarding. Without happy customers willing to buy a product, a company would not be able to survive. Quality issues such as foreign objects, spoiled or mislabeled product, failure to meet net weight requirements, or a recall can all turn customers away from buying a product. The food industry is a customer-driven market in which some consumers are brand loyal based on a history of high quality or in which a single bad experience with a product will turn them away for a lifetime. With this said, the main role of a quality department is to help ensure that quality issues such as these are eliminated or kept to a minimum to maintain or increase the number of customers purchasing their product.

Fanslau, Melody; Young, Janelle

109

ConTrollo della Qualita Interno: Manuale per i Laboratori di Analisi Chimiche. Quarta Edizione (2011) del Nordtest Reort TR569. Traduzione Italiana. (Internal Quality con Troll: Handbook for Chemical Laboratories. Fourth Edition (2011) of the TR-569. Italian Translation).  

National Technical Information Service (NTIS)

Internal quality control (IQC) is a powerful tool available to analytical laboratories for monitoring the quality of analytical performance, documenting their level of quality and identifying preventive actions and strategies for continuous improvement. I...

A. Menditto M. Patriarcra P. Stacchini

2012-01-01

110

Quality Work, Quality Control in Technical Services.  

ERIC Educational Resources Information Center

Quality in library technical services is explored in light of changes produced by automation. Highlights include a definition of quality; new opportunities and shifting priorities; cataloging (fullness of records, heading consistency, accountability, local standards, automated checking); need for new skills (management, staff); and boons of…

Horny, Karen L.

1985-01-01

111

Approaches to quality management and accreditation in a genetic testing laboratory  

PubMed Central

Medical laboratories, and specifically genetic testing laboratories, provide vital medical services to different clients: clinicians requesting a test, patients from whom the sample was collected, public health and medical-legal instances, referral laboratories and authoritative bodies. All expect results that are accurate and obtained in an efficient and effective manner, within a suitable time frame and at acceptable cost. There are different ways of achieving the end results, but compliance with International Organization for Standardization (ISO) 15189, the international standard for the accreditation of medical laboratories, is becoming progressively accepted as the optimal approach to assuring quality in medical testing. We present recommendations and strategies designed to aid genetic testing laboratories with the implementation of a quality management system, including key aspects such as document control, external quality assessment, internal quality control, internal audit, management review, validation, as well as managing the human side of change. The focus is on pragmatic approaches to attain the levels of quality management and quality assurance required for accreditation according to ISO 15189, within the context of genetic testing. Attention is also given to implementing efficient and effective quality improvement.

Berwouts, Sarah; Morris, Michael A; Dequeker, Elisabeth

2010-01-01

112

Can external quality control improve pig AI efficiency?  

Microsoft Academic Search

External quality control programmes carried out by central laboratories have been long established in human andrology with the aim of enhancing the accuracy and reproducibility of semen assessment. Compared to human, demands on boar semen assessment in AI stations are more complex, with the need both to identify boars with poor ejaculate quality and to monitor individual boar differences for

D. Waberski; A. M. Petrunkina; E. Töpfer-Petersen

2008-01-01

113

Construction Quality Control System of Key Water-Control Project  

Microsoft Academic Search

The quality of key water-control project is important to the improvement of national prosperity, stability and economic development. The quality control in the construction of the key water-control project is much a difficult work. So this paper tries to form a construction quality control system. It mainly contains construction quality pre-control system, construction quality process control system, optimization of the

Wang Qin; He Yabo

2010-01-01

114

QUALITY ASSURRANCE AND THE USE OF A REFERENCE LABORATORY  

Microsoft Academic Search

1. QA\\/QC Air quality monitoring must satisfy certain minimum quality requirements and standards. Measurements, regardless of where and by whom they are carried out, must be comparable to those conducted elsewhere. This is secured through a comprehensive Quality Assurance and Quality Control programme (QA\\/QC). QA\\/QC may be regarded as a chain of activities designed to deliver credible and accurate data.

Bjarne SIVERTSEN

115

Proactive quality paint thickness control using ANFIS  

Microsoft Academic Search

Automotive industries try to develop their technologies to improve quality and to minimize scrapes and wastes. In the paint shop vehicle, quality control generally relies on inspection. Industries try to develop their technologies to improve quality via proactive quality control. This paper investigates the predictability of the paint thickness to reduce defects, using ANFIS. A description of the automobile paint

Reza Radfar; Javad J. Jassbi; Felora Ghoreishi; Sohrab Khanmohammadi; Mahmood Alborzi

2010-01-01

116

Construction Quality Control Systems; A Comparative Analysis.  

National Technical Information Service (NTIS)

Traditionally, construction quality control has been characterized by lack of planning, little management support, and an emphasis on inspection to detect construction errors. In the early 1970's, three quality control systems were developed which conside...

S. H. Shepard

1977-01-01

117

Developing a quality plan at a national laboratory  

SciTech Connect

Los Alamos National Laboratory has recently begun to develop a Laboratory-wide quality program. The author discusses in this talk some of the reasons that have caused many of the Laboratory staff to oppose the introduction of formal quality assurance (QA) programs. In analyzing these reasons, it is found that many of the elements of a good quality program are, in fact, already in use. However, a perception still exists that formal QA is an unnecessary bureaucratic burden. There is fear that the freedom of action essential to a good research and development laboratory will be restricted under a QA program. To address this valid concern, the author proposes that we need to re-examine the real purpose of QA, and suggests a new working definition of the term that may be more readily applicable to a multidisciplinary research and development laboratory. It is clear that we cannot successfully promote useful and effective QA programs unless we are willing to broaden our view and be more flexible in our applications of QA methodologies. The author will report on the results of their approach over the first year. We know that much of our task will be to persuade a skeptical staff that a quality program, thoughtfully prepared and properly used, can be a means not only for maintaining our reputation for excellence but also for systematically re-evaluating and improving the way we do our work. We are hopeful that the Laboratory Quality Plan will provide an effective first step toward that goal. 2 refs.

Davis, A.H.

1988-01-01

118

Testing a Constrained MPC Controller in a Process Control Laboratory  

ERIC Educational Resources Information Center

This paper describes an experiment performed by the fourth year chemical engineering students in the process control laboratory at the University of Waterloo. The objective of this experiment is to test the capabilities of a constrained Model Predictive Controller (MPC) to control the operation of a Double Pipe Heat Exchanger (DPHE) in real time.…

Ricardez-Sandoval, Luis A.; Blankespoor, Wesley; Budman, Hector M.

2010-01-01

119

A low cost, scalable, virtual control laboratory  

Microsoft Academic Search

This work presents a virtual control laboratory, based on a single board heater system and free and open source software, such as Scilab, Xcos, Java, PHP\\/MySQL and GNU\\/Linux. This solution allows of the order of 20 devices to be handled by a single Server PC. It allows many students to carry out control experiments remotely. It has been extensively tested

Inderpreet Arora; Kannan M. Moudgalya; Kaushik Venkata; Victor Chakraborty; Rupak Rokade

2011-01-01

120

Quality management systems for your in vitro fertilization clinic's laboratory: Why bother?  

PubMed Central

Several countries have in recent years introduced prescribed requirements for treatment and monitoring of outcomes, as well as a licensing or accreditation requirement for in vitro fertilization (IVF) clinics and their laboratories. It is commonplace for Assisted Reproductive Technology (ART) laboratories to be required to have a quality control system. However, more effective Total Quality Management systems are now being implemented by an increasing number of ART clinics. In India, it is now a requirement to have a quality management system in order to be accredited and to help meet customer demand for improved delivery of ART services. This review contains the proceedings a quality management session at the Indian Fertility Experts Meet (IFEM) 2010 and focuses on the creation of a patient-oriented best-in-class IVF laboratory.

Olofsson, Jan I; Banker, Manish R; Sjoblom, Late Peter

2013-01-01

121

A Laboratory Testbed for Embedded Fuzzy Control  

ERIC Educational Resources Information Center

This paper presents a novel scheme called "Laboratory Testbed for Embedded Fuzzy Control of a Real Time Nonlinear System." The idea is based upon the fact that project-based learning motivates students to learn actively and to use their engineering skills acquired in their previous years of study. It also fosters initiative and focuses students'…

Srivastava, S.; Sukumar, V.; Bhasin, P. S.; Arun Kumar, D.

2011-01-01

122

Mars Science Laboratory thermal control architecture  

NASA Technical Reports Server (NTRS)

The Mars Science Laboratory (MSL) mission to land a large rover on Mars is being planned for launch in 2009. This paper will describe the basic architecture of the thermal control system, the challenges and the methods used to overcome them by the use of an innovative architecture to maximize the use of heritage from past projects while meeting the requirements for the design.

Bhandari, Pradeep; Birur, Gajanana; Pauken, Michael; Paris, Anthony; Novak, Keith; Prina, Mauro; Ramirez, Brenda; Bame, David

2005-01-01

123

Quality assurance in the HIV/AIDS laboratory network of China  

PubMed Central

Background In 2009, there were 8273 local screening laboratories, 254 confirmatory laboratories, 35 provincial confirmatory central laboratories and 1 National AIDS Reference Laboratory (NARL) in China. These laboratories were located in Center for Disease Control and Prevention (CDC) facilities, hospitals, blood donation clinics, maternal and child health (MCH) hospitals and border health quarantine health-care facilities. Methods The NARL and provincial laboratories provide quality assurance through technical, bio-safety and managerial training; periodic proficiency testing; on-site supervisory inspections; and commercial serologic kit evaluations. Results From 2002 to 2009, more than 220 million HIV antibody tests were performed at screening laboratories, and all reactive and indeterminate samples were confirmed at confirmatory laboratories. The use of highly technically complex tests, including CD4 cell enumeration, viral load, dried blood spot (DBS)-based early infant diagnosis (EID), drug resistance (DR) genotyping, HIV-1 subtyping and incidence assays, have increased in recent years and their performance quality is closely monitored. Conclusion China has made significant progress in establishing a well-coordinated HIV laboratory network and QA systems. However, the coverage and intensity of HIV testing and quality assurance programmes need to be strengthened so as to ensure that more infected persons are diagnosed and that they receive timely prevention and treatment services.

Jiang, Yan; Qiu, Maofeng; Zhang, Guiyun; Xing, Wenge; Xiao, Yao; Pan, Pinliang; Yao, Jun; Ou, Chin-Yih; Su, Xueli

2010-01-01

124

Effective laboratory quality management towards preventing medical liability cases  

Microsoft Academic Search

The last decade has seen a rapid expansion of the various branches of health care services in India. This has seen a corresponding increase in consumer knowledge, which has resulted in (a) increased demand for high quality services and (b) these services to be provided in a timely manner. Medical laboratory plays a central role in the delivery of these

A. S. Kanagasabapathy

2010-01-01

125

Harmonization of quality indicators in laboratory medicine. A preliminary consensus.  

PubMed

Abstract Quality indicators (QIs) are fundamental tools for enabling users to quantify the quality of all operational processes by comparing it against a defined criterion. QIs data should be collected over time to identify, correct, and continuously monitor defects and improve performance and patient safety by identifying and implementing effective interventions. According to the international standard for medical laboratories accreditation, the laboratory shall establish and periodically review QIs to monitor and evaluate performance throughout critical aspects of pre-, intra-, and post-analytical processes. However, while some interesting programs on indicators in the total testing process have been developed in some countries, there is no consensus for the production of joint recommendations focusing on the adoption of universal QIs and common terminology in the total testing process. A preliminary agreement has been achieved in a Consensus Conference organized in Padua in 2013, after revising the model of quality indicators (MQI) developed by the Working Group on "Laboratory Errors and Patient Safety" of the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC). The consensually accepted list of QIs, which takes into consideration both their importance and applicability, should be tested by all potentially interested clinical laboratories to identify further steps in the harmonization project. PMID:24622792

Plebani, Mario; Astion, Michael L; Barth, Julian H; Chen, Wenxiang; de Oliveira Galoro, César A; Escuer, Mercedes Ibarz; Ivanov, Agnes; Miller, Warren G; Petinos, Penny; Sciacovelli, Laura; Shcolnik, Wilson; Simundic, Ana-Maria; Sumarac, Zorica

2014-07-01

126

Quality assurance and quality control in monitoring programs.  

PubMed

There are three general characteristics of the data to be collected in a monitoring program that should be met in order to maximize the use and value of the data: the data quality should be known, the data type and quality should be consistent and comparable, and the data should be available and accessible. Potential problems with each of these characteristics are addressed effectively by quality assurance and quality control. One of the most important aspects of quality assurance in a monitoring program is the development of a quality assurance plan, which should identify clearly the quality of the data needed and describe in detail the planned actions to provide confidence that the program will meet its stated objectives.Quality control data, which allow for the quality and suitability of the environmental data to be evaluated and ascertained, should be collected and utilized as an integral part of the QA effort associated with a monitoring program. PMID:24220829

Shampine, W J

1993-07-01

127

Los Alamos National Laboratory Yucca Mountain Site Characterization Project 1994 quality program status report  

SciTech Connect

This status report is for calendar year 1994. It summarizes the annual activities and accomplishments of the Los Alamos National Laboratory Yucca Mountain Site Characterization Project (YMP or Project) quality assurance program. By identifying the accomplishments of the quality program, a baseline is established that will assist in decision making, improve administrative controls and predictability, and allow us to annually identify adverse trends and to evaluate improvements. This is the fourth annual status report.

Bolivar, S.L.

1996-03-01

128

Quality Control by Artificial Vision  

SciTech Connect

Computational technology has fundamentally changed many aspects of our lives. One clear evidence is the development of artificial-vision systems, which have effectively automated many manual tasks ranging from quality inspection to quantitative assessment. In many cases, these machine-vision systems are even preferred over manual ones due to their repeatability and high precision. Such advantages come from significant research efforts in advancing sensor technology, illumination, computational hardware, and image-processing algorithms. Similar to the Special Section on Quality Control by Artificial Vision published two years ago in Volume 17, Issue 3 of the Journal of Electronic Imaging, the present one invited papers relevant to fundamental technology improvements to foster quality control by artificial vision, and fine-tuned the technology for specific applications. We aim to balance both theoretical and applied work pertinent to this special section theme. Consequently, we have seven high-quality papers resulting from the stringent peer-reviewing process in place at the Journal of Electronic Imaging. Some of the papers contain extended treatment of the authors work presented at the SPIE Image Processing: Machine Vision Applications conference and the International Conference on Quality Control by Artificial Vision. On the broad application side, Liu et al. propose an unsupervised texture image segmentation scheme. Using a multilayer data condensation spectral clustering algorithm together with wavelet transform, they demonstrate the effectiveness of their approach on both texture and synthetic aperture radar images. A problem related to image segmentation is image extraction. For this, O'Leary et al. investigate the theory of polynomial moments and show how these moments can be compared to classical filters. They also show how to use the discrete polynomial-basis functions for the extraction of 3-D embossed digits, demonstrating superiority over Fourier-basis functions for this task. Image registration is another important task for machine vision. Bingham and Arrowood investigate the implementation and results in applying Fourier phase matching for projection registration, with a particular focus on nondestructive testing using computed tomography. Readers interested in enriching their arsenal of image-processing algorithms for machine-vision tasks should find these papers enriching. Meanwhile, we have four papers dealing with more specific machine-vision tasks. The first one, Yahiaoui et al., is quantitative in nature, using machine vision for real-time passenger counting. Occulsion is a common problem in counting objects and people, and they circumvent this issue with a dense stereovision system, achieving 97 to 99% accuracy in their tests. On the other hand, the second paper by Oswald-Tranta et al. focuses on thermographic crack detection. An infrared camera is used to detect inhomogeneities, which may indicate surface cracks. They describe the various steps in developing fully automated testing equipment aimed at a high throughput. Another paper describing an inspection system is Molleda et al., which handles flatness inspection of rolled products. They employ optical-laser triangulation and 3-D surface reconstruction for this task, showing how these can be achieved in real time. Last but not least, Presles et al. propose a way to monitor the particle-size distribution of batch crystallization processes. This is achieved through a new in situ imaging probe and image-analysis methods. While it is unlikely any reader may be working on these four specific problems at the same time, we are confident that readers will find these papers inspiring and potentially helpful to their own machine-vision system developments.

Lam, Edmond Y. [University of Hong Kong, The; Gleason, Shaun Scott [ORNL; Niel, Kurt S. [Upper Austria University of Applied Science, Engineering and Environmental Studies

2010-01-01

129

Quality Control of EUVE Databases  

NASA Astrophysics Data System (ADS)

The publicly accessible databases for the Extreme Ultraviolet Explorer (EUVE) include: the EUVE Archive Mailserver, the Center for EUV Astrophysics ftp site, the EUVE Guest Observer Mailserver, and the Astronomical Data System node. The EUVE Performance Assurance team is responsible for verifying that these public databases are working properly and that the public availability of EUVE data contained therein does not infringe any data rights which may have been assigned. In this paper, we describe the quality assurance (QA) procedures we have developed from approaching QA as a service organization; this approach reflects the overall EUVE philosophy of QA integrated into normal operating procedures, rather than imposed as an external, post-facto, control mechanism.

John, Linda M.

1993-01-01

130

Laboratory cost control and financial management software.  

PubMed

Economical constraints within the health care system advocate the introduction of tighter control of costs in clinical laboratories. Detailed cost information forms the basis for cost control and financial management. Based on the cost information, proper decisions regarding priorities, procedure choices, personnel policies and investments can be made. This presentation outlines some principles of cost analysis, describes common limitations of cost analysis, and exemplifies use of software to achieve optimized cost control. One commercially available cost analysis software, LabCost, is described in some detail. In addition to provision of cost information, LabCost also serves as a general management tool for resource handling, accounting, inventory management and billing. The application of LabCost in the selection process of a new high throughput analyzer for a large clinical chemistry service is taken as an example for decisions that can be assisted by cost evaluation. It is concluded that laboratory management that wisely utilizes cost analysis to support the decision-making process will undoubtedly have a clear advantage over those laboratories that fail to employ cost considerations to guide their actions. PMID:9541753

Mayer, M

1998-02-01

131

40 CFR 51.359 - Quality control.  

Code of Federal Regulations, 2010 CFR

...that inspection, calibration records, and control charts are accurately created, recorded...adjust calibration schedules and other quality control frequencies by using statistical process control to monitor equipment performance on an...

2010-07-01

132

40 CFR 51.359 - Quality control.  

Code of Federal Regulations, 2010 CFR

...that inspection, calibration records, and control charts are accurately created, recorded...adjust calibration schedules and other quality control frequencies by using statistical process control to monitor equipment performance on an...

2009-07-01

133

Gradient algorithm applied to laboratory quantum control  

SciTech Connect

The exploration of a quantum control landscape, which is the physical observable as a function of the control variables, is fundamental for understanding the ability to perform observable optimization in the laboratory. For high control variable dimensions, trajectory-based methods provide a means for performing such systematic explorations by exploiting the measured gradient of the observable with respect to the control variables. This paper presents a practical, robust, easily implemented statistical method for obtaining the gradient on a general quantum control landscape in the presence of noise. In order to demonstrate the method's utility, the experimentally measured gradient is utilized as input in steepest-ascent trajectories on the landscapes of three model quantum control problems: spectrally filtered and integrated second harmonic generation as well as excitation of atomic rubidium. The gradient algorithm achieves efficiency gains of up to approximately three times that of the standard genetic algorithm and, as such, is a promising tool for meeting quantum control optimization goals as well as landscape analyses. The landscape trajectories directed by the gradient should aid in the continued investigation and understanding of controlled quantum phenomena.

Roslund, Jonathan; Rabitz, Herschel [Department of Chemistry, Princeton University, Princeton, New Jersey 08544 (United States)

2009-05-15

134

Controlled Space Physics Experiments using Laboratory Magnetospheres  

NASA Astrophysics Data System (ADS)

Modern society's reliance on space-based platforms for a variety of economic and geopolitical purposes makes understanding the physics of the magnetosphere and "space weather'' one of the most important applications of plasma science. During the past decade, results from the CTX and LDX laboratory magnetospheres and from the RT-1 device at University of Tokyo, we have developed techniques to explore space physics using controlled experiments in laboratory magnetospheres. This presentation briefly reviews observations from the laboratory magnetospheres at Columbia University and MIT, including adiabatic drift-resonant transport, low-frequency MHD turbulence, and the formation of high-beta plasmas with profiles similar to Earth's inner magnetosphere. First principle validation of ``whole plasma'' space weather models have been completed in relevant magnetic geometry, including the spectrum and dynamics of turbulence successfully modeled with nonlinear bounce-averaged gyrokinetic simulations. Plans to explore Alfvénic dynamics and whistler wave trapping are discussed through the achievement of higher-density plasmas using radio-frequency heating. Photographs of the laboratory magnetospheres located at MIT (top) and Columbia University (bottom).

Mauel, M. E.; Kesner, J.; Garnier, D.

2013-12-01

135

[Comparative observations of internal and external quality controls in the districts of Neubrandenburg and Rostock].  

PubMed

A useful combination of results from internal quality control and external quality assessment is possible only if the statistical procedures of both systems involve the same limits to accept control data. These limits are shown. For 45 laboratories expected quality groups QG-T are calculated from results of internal quality control. Quality groups QG-RVL are calculated from results of external quality control assessment. In 30 cases the great difference of QG-T and QG-RVL is supposed to be caused by inaccurate performance of internal quality control. PMID:2815919

Krause, H; Lutter, J; Wachsmuth, U; Schmidt, F K; Dummler, W

1989-01-01

136

[Implementation of the technical requirements of the UNE-EN-ISO 15189 quality standard in a mycobacterial laboratory].  

PubMed

The UNE-EN-ISO 15189:2007 standard defines the requirements for quality and competence that must be met by medical laboratories. These laboratories should use this international standard to develop their own quality management systems and to evaluate their own competencies; in turn, this standard will be used by accreditation bodies to confirm or recognize the laboratories' competence. In clinical microbiology laboratories, application of the standard implies the implementation of the technical and specific management requirements that must be met to achieve optimal quality when carrying out microbiological tests. In Spain, accreditation is granted by the Spanish Accreditation Body (Entidad Nacional de Acreditación). This review aims to discuss the practical application of the standard's technical requirements in mycobacterial laboratory. Firstly, we define the scope of accreditation. Secondly, we specify how the items of the standard on personnel management, control of equipment, environmental facilities, method validation, internal controls and customer satisfaction surveys were developed and implemented in our laboratory. PMID:23453231

Guna Serrano, M del Remedio; Ocete Mochón, M Dolores; Lahiguera, M José; Bresó, M Carmen; Gimeno Cardona, Concepción

2013-02-01

137

Control of Weld Quality in Large Welded Populations,  

National Technical Information Service (NTIS)

The use of factorial experimental design during weld procedure development, as a statistical tool for the control of weld quality in large welded populations, is investigated. It is applied to single pass welds made in the laboratory using the spacer to t...

P. J. Alberry R. R. L. Brunnstrom J. A. Lambert R. A. Willgoss

1988-01-01

138

DEVELOPMENT OF SUSPENDED SOLIDS QUALITY CONTROL AND PERFORMANCE EVALUATION SAMPLES  

EPA Science Inventory

A two phase study was conducted to develop a synthetic suspended solids sample for use as quality control check and performance evaluation within environmental monitoring laboratories. The first phase consisted of a feasibility study to determine compounds that exhibited the opti...

139

Colorado Air Quality Control Regulations and Ambient Air Quality Standards.  

ERIC Educational Resources Information Center

Regulations and standards relative to air quality control in Colorado are defined in this publication. Presented first are definitions of terms, a statement of intent, and general provisions applicable to all emission control regulations adopted by the Colorado Air Pollution Control Commission. Following this, three regulations are enumerated: (1)…

Colorado State Dept. of Health, Denver. Div. of Air Pollution Control.

140

Association between product quality control and process quality control of bulk milk  

Microsoft Academic Search

Assessment of dairy-milk quality is based on product quality control (testing bulk-milk samples) and process quality control (auditing dairy farms). It is unknown whether process control improves product quality. To quantify possible association between product control and process control a statistical analysis was conducted. The analysis comprised 64.373 audit results on 26,953 dairy farms and all conducted lab tests of

A. Velthuis; Asseldonk van M. A. P. M

2010-01-01

141

Quality analysis\\/quality control tests for field stabilization\\/solidification — 1. Dry cementing additives  

Microsoft Academic Search

As part of a field validation study of their proposed protocol for solidified waste evaluation, which will correlate laboratory test results with field behaviour, the Wastewater Technology Centre investigated the applicability of several rapid tests for quality analysis and control of the field solidified waste. A pilot-scale landfill was constructed and 63 m3 solidified arc furnace dust placed in it

C. Shi; J. A. Stegemann; R. J. Caldwell

1995-01-01

142

Quality control charts for storage of pears  

Microsoft Academic Search

a   and b values) are the quality factors used for the construction of quality control charts. These charts will be helpful in maintaining\\u000a the inevitable quality loss to within acceptable limits and in readjusting the storage conditions if the acceptable limits\\u000a are exceeded.

G. ?umnu

2000-01-01

143

Quality Control in the Application Process.  

ERIC Educational Resources Information Center

The Georgia Southern University admissions office implemented Total Quality Management (TQM) principles to control the quality of information management. It is suggested that, although TQM is used best on an institutionwide basis, it can also be useful in improving quality, reducing cost, increasing productivity, and achieving competitiveness on a…

Wasson, Dale

1993-01-01

144

Control quality enhancement using fractional PI  

Microsoft Academic Search

The proportional–integral–derivative (PID) controllers have remained, by far, the most commonly and practically used in all industrial feedback control applications; therefore, there is a continuous effort to improve the system control quality performances. More recently Podlubny has proposed the fractional PID controller, a generalisation of the classical PID controller, involving an integration action of order ? and differentiation action of

Khalfa Bettou; Abdelfatah Charef

2009-01-01

145

Water quality control in open channels  

Microsoft Academic Search

With the increasing degree of automation in Dutch water management the need for control systems and design procedures for control systems is also evolving. Traditionally these control systems were used for water level and discharge control only. With the measurement equipment that is currently available, improved water quality control also becomes possible. A PhD researcher is currently investigating the theoretical

A. Hof; W. Schuurmans

146

Dietary Supplement Laboratory Quality Assurance Program: The First Five Exercises  

PubMed Central

The National Institute of Standards and Technology (NIST) has established a Dietary Supplement Laboratory Quality Assurance Program (DSQAP) in collaboration with the National Institutes of Health Office of Dietary Supplements. Program participants measure concentrations of active and/or marker compounds as well as nutritional and toxic elements in food and dietary supplements distributed by NIST. Data are compiled at NIST, where they are analyzed for accuracy relative to reference values and concordance among the participants. Performance reports and certificates of completion are provided to participants, which can be used to demonstrate compliance with current Good Manufacturing Practices as promulgated by the U.S. Food and Drug Administration. The DSQAP has conducted five exercises to date, with total participation including more than 75 different laboratories and many more individual analysts.

Phillips, Melissa M.; Rimmer, Catherine A.; Wood, Laura J.; Lippa, Katrice A.; Sharpless, Katherine E.; Duewer, David L.; Sander, Lane C.; Betz, Joseph M.

2011-01-01

147

Quality-assurance program for field health laboratories  

SciTech Connect

The Federal Mine Safety and Health Act of 1977 (and previously the Federal Coal Mine Health and Safety Act of 1969) established mandatory dust standards for coal mines. Title II requires the Secretary of Labor to make frequent inspections of coal mines to determine compliance with the mandated 2.0 mg/cu m respirable-dust standard. Such inspections are made by representatives of the Secretary, who are coal-mine inspectors of the Mine Safety and Health Administration (MSHA). Sampling equipment used to assess respirable dust concentrations is calibrated and maintained at local field laboratories located in each Coal Mine Safety and Health district. Samples collected during inspections are weighed and analyzed at these laboratories. A selected number of laboratories are also qualified to weigh operator samples in accordance with provisions promulgated in Title 30, Code of Federal Regulations, Part 70. This paper describes the quality-assurance program conducted to assure the performance integrity of the field laboratories in the maintenance and calibration of respirable-dust-sampling equipment and the weighing of respirable coal mine dust samples.

Treaftis, H.N.; Parobeck, P.S.

1984-01-01

148

33 CFR 385.21 - Quality control.  

Code of Federal Regulations, 2013 CFR

...shall prepare a quality control plan...regulations, for each product that will be produced...Delivery Team. The quality control plan shall...included in the Project Management Plan and shall... (b) During development of the Project Management...reviews to ensure that products are...

2013-07-01

149

International external quality assurance for laboratory diagnosis of diphtheria.  

PubMed

The diphtheria surveillance network (DIPNET) encompassing National Diphtheria Reference Centers from 25 European countries is a Dedicated Surveillance Network recognized by the European Commission. A key DIPNET objective is the quality assessment of microbiological procedures for diphtheria across the European Union and beyond. A detailed questionnaire on the level of reference laboratory services and an external quality assessment (EQA) panel comprising six simulated throat specimens were sent to 34 centers. Twenty-three centers are designated National Diphtheria Reference Centers, with the laboratory in the United Kingdom being the only WHO Collaborating Centre. A variety of screening and identification tests were used, including the cysteinase test (20/34 centers), pyrazinamidase test (17/34 centers), and commercial kits (25/34 centers). The classic Elek test for toxigenicity testing is mostly used (28/34 centers), with variations in serum sources and antitoxin concentrations. Many laboratories reported problems obtaining Elek reagents or media. Only six centers produced acceptable results for all six specimens. Overall, 21% of identification and 13% of toxigenicity reports were unacceptable. Many centers could not isolate the target organism, and most found difficulties with the specimens that contained Corynebacterium striatum as a commensal contaminant. Nineteen centers generated either false-positive or negative toxigenic results, which may have caused inappropriate medical management. The discrepancies in this diphtheria diagnostics EQA alarmingly reflect the urgent need to improve laboratory performance in diphtheria diagnostics in Europe, standardize feasible and robust microbiological methods, and build awareness among public health authorities. Therefore, DIPNET recommends that regular workshops and EQA distributions for diphtheria diagnostics should be supported and maintained. PMID:19828749

Neal, S E; Efstratiou, A

2009-12-01

150

Laboratory facility design and microbial indoor air quality in selected hospital laboratories.  

PubMed

Hospital laboratory is one of workplace areas contaminated with a variety of biohazards. A cross sectional study was conducted to assess the microbial air quality and facility design in the laboratories of four selected governmental hospitals (Hospitals A, B, C, and D) in Bangkok, Thailand. One hundred eighty-eight indoor air samples were collected from 40 laboratory rooms to investigate bacterial and fungal counts using the Millipore air tester. Forty air samples were collected from the waiting areas of those laboratories, and 16 outdoor air samples were collected to use for comparison. Additionally, those laboratory facilities were assessed following biosafety facility design (10 items). Results indicated that the facility design of laboratory in the Hospital A met most of items of the biosafety facility criteria. The rest met only seven items of the criteria. Means +/- standard deviation (SD) of bacterial counts of 253.1 +/- 247.7 cfu/m3, 236.8 +/- 200.1 cfu/m3, 304.4 +/- 264.2 cfu/m3, and 146.7 +/- 127.0 cfu/m3, and fungal counts of 500.8 +/- 64.2 cfu/ m3, 425.0 +/- 21.2 cfu/m3, 357.0 +/- 121.2 cfu/m3, and 355.7 +/- 86.8 cfu/m3 were found in hospital laboratories A, B, C and D, respectively. The isolated colonies of bacteria and fungi were identified as group or genus. It was found that the most common bacteria was Staphylococcus spp (84.1%, 76.0%, 72.1% and 80.5%, respectively), whereas, the most common fungi were Aspergillus spp and septate hyphae fungi (42.0%, 37.5%, 39.5%, and 45.7%; vs 38.6%, 56.2%, 52.1%, and 37.2%, respectively). These data may be valuable to develop interventions to improve the microbial indoor air quality among hospital laboratories and for preventing the laboratory-acquired infections. PMID:24974659

Luksamijarulkul, Pipat; Kiennukul, Nuchanard; Vatthanasomboon, Pisit

2014-05-01

151

Research on software quality control method based on control chart  

Microsoft Academic Search

Improving the software quality unceasingly, is an important work of throughout the software life cycle, is a reliable guarantee of software projects which is successful implemented and completed. For the problems exist in the process of software quality management, researching with control chart. Based on the study of control chart theory, control chart application examples are given. The research of

Yongchang Ren; Deyi Jiang; Tao Xing; Ping Zhu

2011-01-01

152

30 CFR 28.31 - Quality control plans; contents.  

Code of Federal Regulations, 2013 CFR

...TRAILING CABLES IN COAL MINES Quality Control § 28.31 Quality control plans; contents. (a) Each quality control plan shall contain provisions for the management of quality, including: (1) Requirements for the production of...

2013-07-01

153

Technological operations in quality control of concrete  

NASA Astrophysics Data System (ADS)

Results of Finnish and Soviet cooperative research in producing quality concrete for the construction industry are reported in 10 conference papers. Topics covered include: quality ensurance for front surfaces on enclosed structures; high temperature treatment of concrete while producing precast products; a complex system for producing quality control at precast concrete factories; roll pressing flat concrete and reinforced concrete products; creating a thermally active protective layer of concrete for accelerating the hardening of large size products; infrared heating of concrete in construction site conditions; national codes for winter concreting; quality control tests for frost resistance; compressive strength of concrete using NDT; and accelerated life tests in Finland.

1981-09-01

154

Process control by quality charting  

Microsoft Academic Search

The efficiency of automated process control depends on the used statistical process control technique intended for testing uniformity and stability, representing two major process characteristics. Stability characterizes the statistical process behavior, whereas uniformity reflects the ability of the process to yield the products with the same (or similar) properties. Control charts, representing one of the main tools in statistical process

Z. Bluvband; P. Grabov

1994-01-01

155

Maintaining data quality in an environmental testing laboratory  

SciTech Connect

In today's competitive and highly litigious world, it is critical that any laboratory generating data for the environmental and allied industries have a world-class Quality Assurance Program. This Plan must conform to the requirements of every agency and client with whom the lab does business. The goal of such a program is data defensibility; i.e., data validity. Data (usually qualitative analyte [compound or element] identifications and quantitative numerical results) are the end results of nearly all analytical laboratory processes, and the source of revenue. Clients pay for results. The clients expect the results to be accurate, precise, and repeatable. If their data has to go to court, the laboratory will be called upon to defend the accuracy and precision of their work. Without a strong QA program, this will be impossible. The potential implications and repercussions of non-defensible lab data are far-reaching and very costly in terms of loss of future revenues and in legal judgments.

Cohen, Roy J.

2001-03-05

156

Water Quality Control, Curriculum Guide.  

ERIC Educational Resources Information Center

Activities which study how water is used, contaminated, and treated or purified are presented in this curriculum guide, culminating in the investigation of a local water quality problem. Designed as a 12 week mini-course for students in grades eight and nine, the guide first presents a review of the content, objectives, major concepts, and sources…

Washington City Board of Education, NC.

157

Control by quality: proposition of a typology.  

PubMed

The application of Quality tools and methods in industrial management has always had a fundamental impact on the control of production. It influences the behavior of the actors concerned, while introducing the necessary notions and formalizations, especially for production systems with little or no automation, which constitute a large part of the industrial activity. Several quality approaches are applied in the workshop and are implemented at the level of the control. In this paper, the authors present a typology of the various approaches that have successively influenced control, such as statistical process control, quality assurance, and continuous improvement. First the authors present a parallel between production control and quality organizational structure. They note the duality between control, which is aimed at increasing productivity, and quality, which aims to satisfy the needs of the customer. They also note the hierarchical organizational structure of these two systems of management with, at each level, the notion of a feedback loop. This notion is fundamental to any kind of decision making. The paper is organized around the operational, tactical, and strategic levels, by describing for each level the main methods and tools for control by quality. The overview of these tools and methods starts at the operational level, with the Statistical Process Control, the Taguchi technique, and the "six sigma" approach. On the tactical level, we find a quality system approach, with a documented description of the procedures introduced in the firm. The management system can refer here to Quality Assurance, Total Productive Maintenance, or Management by Total Quality. The formalization through procedures of the rules of decision governing the process control enhances the validity of these rules. This leads to the enhancement of their reliability and to their consolidation. All this counterbalances the human, intrinsically fluctuating, behavior of the control operators. Strategic control by quality is then detailed, and the two main approaches, the continuous improvement approach and the proactive improvement approach, are introduced. Finally, the authors observe that at each of the three levels, the continuous process improvement, which is a component of Total Quality, becomes an essential preoccupation for the control. Ultimately, the recursive utilization of the Deming cycle remains the best practice for the control by quality. PMID:12512551

Pujo, P; Pillet, M

158

Controller Design of Power Quality-Improving Appliances  

SciTech Connect

This paper presents an innovative solution to power quality problems using power quality-improving (PQI) appliances. PQI appliances conduct currents that supplement and correct the sum of the other load currents within a premise. From the utility side, the premise housing a PQI appliance thus becomes an improved, if not ideal, utility customer. The PQI appliance improves both harmonic power quality and power factor while performing its normal function, such as heating water. In this paper, the water heater PQI appliance is used as an example to demonstrate the control circuit design and function. Both computer simulation results and laboratory experiment results are presented to demonstrate the effectiveness of the approach. The estimated costs of the PQI controller and of harmonic compensating filters are compared to show that the PQI appliance may be an economic way to provide power quality improvement at the building level.

Hammerstrom, Donald J.; Zhou, Ning; Lu, Ning

2007-05-01

159

[Pharmaceutical product quality control and good manufacturing practices].  

PubMed

This report describes the roles of Good Manufacturing Practices (GMP) in pharmaceutical product quality control. There are three keys to pharmaceutical product quality control. They are specifications, thorough product characterization during development, and adherence to GMP as the ICH Q6A guideline on specifications provides the most important principles in its background section. Impacts of the revised Pharmaceutical Affairs Law (rPAL) which became effective in 2005 on product quality control are discussed. Progress of ICH discussion for Pharmaceutical Development (Q8), Quality Risk Management (Q9) and Pharmaceutical Quality System (Q10) are reviewed. In order to reconstruct GMP guidelines and GMP inspection system in the regulatory agencies under the new paradigm by rPAL and the ICH, a series of Health Science studies were conducted. For GMP guidelines, product GMP guideline, technology transfer guideline, laboratory control guideline and change control system guideline were written. For the GMP inspection system, inspection check list, inspection memo and inspection scenario were proposed also by the Health Science study groups. Because pharmaceutical products and their raw materials are manufactured and distributed internationally, collaborations with other national authorities are highly desired. In order to enhance the international collaborations, consistent establishment of GMP inspection quality system throughout Japan will be essential. PMID:21381389

Hiyama, Yukio

2010-01-01

160

Quality control of pumps for nuclear applications  

Microsoft Academic Search

The new generation of primary pumps for PWR-type reactors have evolved ; rapidly resulting in groups with a classical electric motor involving pumps with ; controlled leaks with higher and higher power. The present control technlques ; have followed and even preceded this evolution. The various quality control ; agencies during development of the groups and notably the project revision,

Vuckovic

1973-01-01

161

The Effectiveness of Quality Control Charts  

Microsoft Academic Search

The spacing and effectiveness functions of a quality control chart used either alone or in sets of two or more are derived for production at a constant level and for erratic production. The spacing of decision points is considered from a general point of view. The theory developed is fundamental in deciding which of two different decision techniques in quality

Leo A. Aroian; Howard Levene

1950-01-01

162

CLAY LINER CONSTRUCTION AND QUALITY CONTROL  

EPA Science Inventory

Soil handling and liner construction practices at hazardous waste management facilities are documented. Soil characterizations, processing techniques, construction methods, and quality control of constructed liners are reviewed and compared. Results indicate widely different test...

163

Metallographic Quality Control of Welding and Brazing.  

National Technical Information Service (NTIS)

The value of metallography in assuring integrity in the fabrication of metal and components in energy systems is summarized. Metallography also plays an integral role in quality control of welded and brazed joints. (ERA citation 04:048890)

G. M. Slaughter

1979-01-01

164

Quality assurance plan for Waste Area Grouping 6 at Oak Ridge National Laboratory, Oak Ridge, Tennessee  

SciTech Connect

This Quality Assurance Plan (QAP) is concerned with design and construction (Sect. 2) and characterization and monitoring (Sect. 3). The basis for Sect. 2 is the Quality Assurance Plan for the Design and Construction of Waste Area Grouping 6 Closure at Oak Ridge National Laboratory, Oak Ridge, Tennessee, and the basis for Sect. 3 is the Environmental Restoration Quality Program Plan. Combining the two areas into one plan gives a single, overall document that explains the requirements and from which the individual QAPs and quality assurance project plans can be written. The Waste Area Grouping (WAG) 6 QAP establishes the procedures and requirements to be implemented for control of quality-related activities for the WAG 6 project. Quality Assurance (QA) activities are subject to requirements detailed in the Martin Marietta Energy Systems, Inc. (Energy Systems), QA Program and the Environmental Restoration (ER) QA Program, as well as to other quality requirements. These activities may be performed by Energy Systems organizations, subcontractors to Energy Systems, and architect-engineer (A-E) under prime contract to the US Department of Energy (DOE), or a construction manager under prime contract to DOE. This plan specifies the overall Energy Systems quality requirements for the project. The WAG 6 QAP will be supplemented by subproject QAPs that will identify additional requirements pertaining to each subproject.

Not Available

1994-01-01

165

Description of the Spacecraft Control Laboratory Experiment (SCOLE) facility  

NASA Technical Reports Server (NTRS)

A laboratory facility for the study of control laws for large flexible spacecraft is described. The facility fulfills the requirements of the Spacecraft Control Laboratory Experiment (SCOLE) design challenge for laboratory experiments, which will allow slew maneuvers and pointing operations. The structural apparatus is described in detail sufficient for modelling purposes. The sensor and actuator types and characteristics are described so that identification and control algorithms may be designed. The control implementation computer and real-time subroutines are also described.

Williams, Jeffrey P.; Rallo, Rosemary A.

1987-01-01

166

Description of the Spacecraft Control Laboratory Experiment (SCOLE) facility  

NASA Technical Reports Server (NTRS)

A laboratory facility for the study of control laws for large flexible spacecraft is described. The facility fulfills the requirements of the Spacecraft Control Laboratory Experiment (SCOLE) design challenge for a laboratory experiment, which will allow slew maneuvers and pointing operations. The structural apparatus is described in detail sufficient for modelling purposes. The sensor and actuator types and characteristics are described so that identification and control algorithms may be designed. The control implementation computer and real-time subroutines are also described.

Williams, Jeffrey P.; Rallo, Rosemary A.

1987-01-01

167

Product liability, quality control and insurance  

Microsoft Academic Search

In order to protect consumers many governments have introduced strict legislation on product liability. Manufacturers can\\u000a then either establish a strict system of quality control, or try to have their liability covered by insurance. Statistical\\u000a quality control will give information about the probability that a consumer shall buy a defective product, and be entitled\\u000a to claim compensation. This probability is

Karl Borch

1978-01-01

168

Aerospace Materials Quality Control: Instructor Notes  

NSDL National Science Digital Library

This document from the Aerospace Manufacturing Education Project is intended to accompany a PowerPoint presentation on the topic of quality control of materials used in the aerospace industry. That presentation is available for download here. The presentation and notes will help students understand why quality control is important in this field. They also include details about aerospace QC teams and techniques, including non-destructive testing. These instructor notes also include links to a number of useful online references.

2012-11-14

169

Quality control of embryo development.  

PubMed

Although in recent years we have seen an undeniable improvement in the field of reproductive biology and medicine, the efficiency of in vitro fertilization (IVF) procedures remains relatively low, ranging from 4% to 40% depending on the patient's age. It is believed that this is in a large part caused by inaccurate assessment of embryo quality prior to transfer to mothers-to-be. Thus there is a strong need for further refinement of existing selection methods and development of novel, robust and, if only possible, non-invasive procedures to ensure that only embryos with the highest developmental potential are chosen for transfer. In the present review we compare various methods for assessing the quality of preimplantation embryos either currently used in IVF clinics or still to be tested. These methods include assessment of embryonic morphology, the genetic material, the transcriptomes of the oocyte and its accompanying follicular cells, and the embryo's metabolism. We discuss what information these parameters actually provide about the processes occurring in the embryo itself. We also present novel methods for selecting healthy embryos based on most recent advanced time-lapse imaging techniques, which show great promise and are likely to lead to increased in vitro fertilization efficiency. PMID:23563243

Ajduk, Anna; Zernicka-Goetz, Magdalena

2013-10-01

170

QUALITY CONTROL FOR RESEARCH STUDIES: A CRITICAL PART OF THE QUALITY SYSTEM AT THE U. S. EPA  

EPA Science Inventory

QUALITY CONTROL FOR RESEARCH STUDIES: A CRITICAL PART OF THE QUALITY SYSTEM AT THE U.S. EPA Mette C.J. Schladweiler, Scientist, and Thomas J. Hughes, QA and Records Manager, Experimental Toxicology Division (ETD), National Health and Environmental Effects Research Laboratory (NHE...

171

Principles of Water Quality Control.  

ERIC Educational Resources Information Center

This book is designed as a text for undergraduate civil engineering courses and as preliminary reading for postgraduate courses in public health engineering and water resources technology. It is also intended to be of value to workers already in the field and to students preparing for the examinations of the Institute of Water Pollution Control

Tebbutt, T. H. Y.

172

Network-based production quality control  

NASA Astrophysics Data System (ADS)

This study investigates the feasibility of remote quality control using a host of advanced automation equipment with Internet accessibility. Recent emphasis on product quality and reduction of waste stems from the dynamic, globalized and customer-driven market, which brings opportunities and threats to companies, depending on the response speed and production strategies. The current trends in industry also include a wide spread of distributed manufacturing systems, where design, production, and management facilities are geographically dispersed. This situation mandates not only the accessibility to remotely located production equipment for monitoring and control, but efficient means of responding to changing environment to counter process variations and diverse customer demands. To compete under such an environment, companies are striving to achieve 100%, sensor-based, automated inspection for zero-defect manufacturing. In this study, the Internet-based quality control scheme is referred to as "E-Quality for Manufacturing" or "EQM" for short. By its definition, EQM refers to a holistic approach to design and to embed efficient quality control functions in the context of network integrated manufacturing systems. Such system let designers located far away from the production facility to monitor, control and adjust the quality inspection processes as production design evolves.

Kwon, Yongjin; Tseng, Bill; Chiou, Richard

2007-09-01

173

Safety in the Chemical Laboratory: Fire Safety and Fire Control in the Chemistry Laboratory.  

ERIC Educational Resources Information Center

Discusses fire safety and fire control in the chemistry laboratory. The combustion process, extinguishing equipment, extinguisher maintenance and location, and fire safety and practices are included. (HM)

Wilbraham, A. C.

1979-01-01

174

Remotely controlled laboratory experiments: Creation and examples  

Microsoft Academic Search

Most users who can only connect to their university through distance learning enabled programs have no other choice than to sit out the experimental side of education. Remote Labs have the greatest potential to overcome the bottleneck in distance education. The goal of Remote Laboratory implementation is to grant these students access to laboratory equipment. Although there is not currently

A. Hyder; S. K. Choi; D. Schaefer

2010-01-01

175

CSF biomarker variability in the Alzheimer's Association quality control program  

PubMed Central

Background The cerebrospinal fluid (CSF) biomarkers amyloid beta 1–42, total tau, and phosphorylated tau are used increasingly for Alzheimer’s disease (AD) research and patient management. However, there are large variations in biomarker measurements among and within laboratories. Methods Data from the first nine rounds of the Alzheimer’s Association quality control program was used to define the extent and sources of analytical variability. In each round, three CSF samples prepared at the Clinical Neurochemistry Laboratory (Mölndal, Sweden) were analyzed by single-analyte enzyme-linked immunosorbent assay (ELISA), a multiplexing xMAP assay, or an immunoassay with electrochemoluminescence detection. Results A total of 84 laboratories participated. Coefficients of variation (CVs) between laboratories were around 20% to 30%; within-run CVs, less than 5% to 10%; and longitudinal within-laboratory CVs, 5% to 19%. Interestingly, longitudinal within-laboratory CV differed between biomarkers at individual laboratories, suggesting that a component of it was assay dependent. Variability between kit lots and between laboratories both had a major influence on amyloid beta 1–42 measurements, but for total tau and phosphorylated tau, between-kit lot effects were much less than between-laboratory effects. Despite the measurement variability, the between-laboratory consistency in classification of samples (using prehoc-derived cutoffs for AD) was high (>90% in 15 of 18 samples for ELISA and in 12 of 18 samples for xMAP). Conclusions The overall variability remains too high to allow assignment of universal biomarker cutoff values for a specific intended use. Each laboratory must ensure longitudinal stability in its measurements and use internally qualified cutoff levels. Further standardization of laboratory procedures and improvement of kit performance will likely increase the usefulness of CSF AD biomarkers for researchers and clinicians.

Mattsson, Niklas; Andreasson, Ulf; Persson, Staffan; Carrillo, Maria C.; Collins, Steven; Chalbot, Sonia; Cutler, Neal; Dufour-Rainfray, Diane; Fagan, Anne M.; Heegaard, Niels H. H.; Hsiung, Ging-Yuek Robin; Hyman, Bradley; Iqbal, Khalid; Lachno, D. Richard; Lleo, Alberto; Lewczuk, Piotr; Molinuevo, Jose L.; Parchi, Piero; Regeniter, Axel; Rissman, Robert; Rosenmann, Hanna; Sancesario, Giuseppe; Schroder, Johannes; Shaw, Leslie M.; Teunissen, Charlotte E.; Trojanowski, John Q.; Vanderstichele, Hugo; Vandijck, Manu; Verbeek, Marcel M.; Zetterberg, Henrik; Blennow, Kaj; Kaser, Stephan A.

2013-01-01

176

Quality assurance of computer controlled radiotherapy treatments.  

PubMed

There is a need in conformal therapy, as in any radiation therapy, for adequate quality assurance of the treatment plan and the delivery of the treatment. This paper examines quality assurance of two methods of conformal treatment, on a cobalt treatment unit using computer control. Each of the two methods demonstrates a different aspect of computer controlled treatments. Following completion of each treatment plan, an additional "quality assurance plan" is prepared. This is used to assess the integrity of the treatment plan, and the precision with which the computer controls the treatment unit. A simple method, using solid state detectors in a Perspex phantom, is used to validate the dosimetry of the "quality assurance plan". Quality assurance of the computer control is performed daily prior to treatments. At each treatment, parameters identifying the start position and final position of the computer controlled couch movements and the exposure time are noted by the radiographers. Comparison of the recorded movement of the treatment couch and the exposure time with that intended during each course of treatment has demonstrated, inter alia, limitations on couch speed control at speeds of less than 10 mm per min. PMID:1611420

Morgan, H M

1992-05-01

177

42 CFR 84.40 - Quality control plans; filing requirements.  

Code of Federal Regulations, 2012 CFR

... 1 2012-10-01 2012-10-01 false Quality control plans; filing requirements. 84.40... APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Quality Control § 84.40 Quality control plans; filing requirements....

2012-10-01

178

21 CFR 640.56 - Quality control test for potency.  

Code of Federal Regulations, 2011 CFR

...2011-04-01 2010-04-01 true Quality control test for potency. 640.56 Section 640.56...Cryoprecipitate § 640.56 Quality control test for potency. (a) Quality control tests for potency of antihemophilic factor...

2011-04-01

179

On Product Liability and Quality Control  

Microsoft Academic Search

Product liability is one of the most costly and confusing problems facing manufacturing today. In this paper, models of the economic impact of both final acceptance sampling and process control on liability risk due to a manufacturing defect are presented. A numerical example reveals that selection of cost-effective quality control methods depends on assumed disposition of rejected lots.

Ann S. Marucheck

1987-01-01

180

Quality control by a mobile molecular workshop: Quality versus quantity  

NASA Astrophysics Data System (ADS)

Ribosome is a molecular machine that moves on a messenger RNA (mRNA) track while, simultaneously, polymerizing a protein using the mRNA also as the corresponding template. We define, and analytically calculate, two different measures of the efficiency of this machine. However, we argue that its performance is evaluated better in terms of the translational fidelity and the speed with which it polymerizes a protein. We define both these quantities and calculate these analytically. Fidelity is a measure of the quality of the products, while the total quantity of products synthesized in a given interval depends on the speed of polymerization. We show that for synthesizing a large quantity of proteins, it is not necessary to sacrifice the quality. We also explore the effects of the quality control mechanism on the strength of mechanochemical coupling. We suggest experiments for testing some of the ideas presented here.

Sharma, Ajeet K.; Chowdhury, Debashish

2010-09-01

181

21 CFR 606.140 - Laboratory controls.  

Code of Federal Regulations, 2011 CFR

...appropriate specifications, standards and test procedures to assure that blood and blood...precision and performance of laboratory test procedures and instruments. (c) Adequate identification and handling of all test samples so that they are accurately...

2011-04-01

182

Quality assurance and quality control for the compact physics research facility (CPRF) and ZTH experiment  

SciTech Connect

In compliance with DOE Order 5700.6B, which establishes policies to assure quality achievement in DOE programs, we instituted a quality assurance and quality control program whose primary goal is to assure that reliable components are available with which to assemble the CPRF/ZTH experiment. The Code of Federal Regulations 10 CFR 50, appendix B, and the ANSI standard N45.2 were used as a primary source of guidance in establishing a plan for our QA program. Accepted codes, such as the National Electric Code (NEC), and standards adopted by organizations such as ANSI, IEEE, ASME, and NEMA were used in the design and production of components in keeping with the primary goal of the CPRF program. In setting up the CPRF/ZTH quality assurance program it was our intention to have these standards apply to all suppliers, both within and outside the Laboratory. 5 refs., 6 figs.

Kewish, R.W. Jr.

1989-01-01

183

Quality control of a teleradiology system  

NASA Astrophysics Data System (ADS)

Teleradiology is being implemented in the U.S. military. Soft-copy reading of computed radiology (CR) images and film-digitizer (FD) images are becoming a common practice. The Medical Diagnostic Imaging Support (MDIS) Office at the Medical Advanced Technology Management Office (MATMO), Fort Detrick, Maryland, installed an 'off-the-shelf' DICOM teleradiology system by which CR images and FD images acquired at Hickam Air Force Base (AFB), Hawaii, are transmitted electronically over a T-1 telecommunications line to Tripler Army Medical Center (TAMC), Hawaii. The goal was to provide a diagnostic quality teleradiology system to the military services to extend the expertise and training of physicians to remote sites. In order to guarantee a diagnostic quality image throughout the system, a rigid set of quality control standards had to be designed and implemented. This poster presents the results of a successful teleradiology implementation where quality control is maintained throughout the imaging chain.

Lyche, David K.; Willis, Charles E.; Williamson, Morgan P.; Suitor, Charles T.; Romlein, John R.

1996-04-01

184

Noninvasive Quality Control of Cryopreserved Samples  

PubMed Central

We present a novel noninvasive technology for quality control in biobanking. We implemented a contactless optical in situ method with a remote detection unit. The method detects physical and chemical changes by emission spectroscopy. In the present study, ice formation in a vitrified sample is revealed by Raman scattering. The technology allows us to monitor sample quality during cold storage and to assess the sample state after preservation, storage, or transport without the need for thawing.

Dorr, Daniel; Stracke, Frank

2012-01-01

185

[Quality control of equipment used for radiotherapy].  

PubMed

Due to the modifications of components, to unexpected breakage of elements or to electronic dysfunctions, the performance of radiotherapy machines may decrease with age. Quality Assurance procedures and maintenance program are necessary to guarantee the performances. For linear accelerators, modus operandi of control tests and their frequency are based on regulations and recommendations widely published, that are presented here. Concerning accessories, especially those recently developed (multileaf collimators, dynamic wedges, ...), recommendations remains to be defined. Simple tests are proposed. Concerning numerical imaging systems, widely used for three dimensional dosimetry, image quality and geometry controls must be performed with phantom tests. For portal imaging, a quality assurance program is proposed. A strict and complete Quality Assurance program is essential to guarantee quality and safety of the treatment. A regular control of linear accelerator is one of the important component of this program. It suppose the implementation of permanent tests procedures, periodically modified following technological progresses and treatment techniques. Measurements must be sensible to variations below the tolerance level defined during the installation process. The analysis of the variations of measurements with time are an objective criterion of quality. PMID:12587396

François, P

2002-11-01

186

QUALITY ASSURANCE GUIDELINES FOR LABORATORIES PERFORMING FORENSIC ANALYSIS OF CHEMICAL TERRORISM  

EPA Science Inventory

The Scientific Working Group on Forensic Analysis of Chemical Terrorism (SWGFACT) has developed the following quality assurance guidelines to provide laboratories engaged in forensic analysis of chemical evidence associated with terrorism a framework to implement a quality assura...

187

[Highly quality-controlled radiation therapy].  

PubMed

Advanced radiation therapy for intracranial disease has focused on set-up accuracy for the past 15 years. However, quality control in the prescribed dose is actually as important as the tumor set-up in radiation therapy. Because of the complexity of the three-dimensional radiation treatment planning system in recent years, the highly quality-controlled prescription of the dose has now been reappraised as the mainstream to improve the treatment outcome of radiation therapy for intracranial disease. The Japanese Committee for Quality Control of Radiation Therapy has developed fundamental requirements such as a QC committee in each hospital, a medical physicist, dosimetrists (QC members), and an external audit. PMID:15853208

Shirato, Hiroki

2005-04-01

188

Post-translational Modification and Quality Control  

PubMed Central

Protein quality control (PQC) functions to minimize the level and toxicity of misfolded proteins in the cell. PQC is performed by intricate collaboration among chaperones and target protein degradation. The latter is carried out primarily by the ubiquitin-proteasome system and perhaps autophagy. Terminally misfolded proteins that are not timely removed tend to form aggregates. Their clearance requires macroautophagy. Macroautophagy serves in intracellular quality control also by selectively segregating defective organelles (e.g., mitochondria) and targeting them for degradation by the lysosome. Inadequate PQC is observed in a large subset of failing human hearts with a variety of etiologies and its pathogenic role has been experimentally demonstrated. Multiple post-translational modifications (PTMs) can occur to substrate proteins and/or PQC machineries, promoting or hindering the removal of the misfolded proteins. This article highlights recent advances in PTMs-mediated regulation of intracellular quality control mechanisms and its known involvement in cardiac pathology.

Wang, Xuejun; Pattison, J. Scott; Su, Huabo

2013-01-01

189

Quality control technique to reduce the variability of longitudinal measurement of hemoglobin mass.  

PubMed

The sensitivity of the athlete blood passport to detect blood doping may be improved by the inclusion of total hemoglobin mass (Hb(mass)), but the comparability of Hb(mass) from different laboratories is unknown. To optimize detection sensitivity, the analytical variability associated with Hb(mass) measurement must be minimized. The aim of this study was to investigate the efficacy of using quality controls to minimize the variation in Hb(mass) between laboratories. Three simulated laboratories were set up in one location. Nine participants completed three carbon monoxide (CO) re-breathing tests in each laboratory. One participant completed two CO re-breathing tests in each laboratory. Simultaneously, quality controls containing Low (1-3%) and High (8-11%) concentrations of percent carboxyhemoglobin (%HbCO) were measured to compare hemoximeters in each laboratory. Linear mixed modeling was used to estimate the within-subject variation in Hb(mass), expressed as the coefficient of variation, and to estimate the effect of different laboratories. The analytic variation of Hb(mass) was 2.4% when tests were conducted in different laboratories, which reduced to 1.6% when the model accounted for between-laboratory differences. Adjustment of Hb(mass) values using quality controls achieved a comparable analytic variation of 1.7%. The majority of between-laboratory variation in Hb(mass) originated from the difference between hemoximeters, which could be eliminated using appropriate quality controls. PMID:21535184

Gough, C E; Sharpe, K; Ashenden, M J; Anson, J M; Saunders, P U; Garvican, L A; Bonetti, D L; Gore, C J; Prommer, N

2011-12-01

190

Advances in quality control for dioxins monitoring and evaluation of measurement uncertainty from quality control data  

Microsoft Academic Search

This paper describes an application of multivariate and multilevel quality control charts with the aim of improving the internal quality control (IQC) procedures for the monitoring of dioxins and dioxin-like PCBs analysis in food. Dioxin analysts have to use the toxic equivalent concept (TEQ) to assess the toxicity potential of a mixture of dioxin-like compounds. The TEQ approach requires quantifying

Gauthier Eppe; Edwin De Pauw

2009-01-01

191

HPLC for quality control of polyimides  

NASA Technical Reports Server (NTRS)

High Pressure Liquid Chromatography (HPLC) as a quality control tool for polyimide resins and prepregs are presented. A data base to help establish accept/reject criteria for these materials was developed. This work is intended to supplement, not replace, standard quality control tests normally conducted on incoming resins and prepregs. To help achieve these objectives, the HPLC separation of LARC-160 polyimide precursor resin was characterized. Room temperature resin aging effects were studied. Graphite reinforced composites made from fresh and aged resin were fabricated and tested to determine if changes observed by HPLC were significant.

Young, P. R.; Sykes, G. F.

1979-01-01

192

Statistical Quality Control in Production of Infusion Solutions  

Microsoft Academic Search

A systematic quality control approach for monitoring the production of infusion solutions in a pharmaceutical plant is introduced. The main features of approach are combining modern quality control technologies with quality information system. Based on the strict quality requirements and the process flow of the production of infusion solutions, a serial suitable statistical quality control methods are selected and discussed.

Yu Zhang; Xiaoqun Cao; Musheng Yang

2009-01-01

193

CONTROL ASSAY DEVELOPMENT: METHODOLOGY AND LABORATORY VERIFICATION  

EPA Science Inventory

The report describes Control Assay Development (CAD), a data acquisition program designed to evaluate the potential applicability of various treatment processes for the control of solid, liquid, and gaseous emissions from coal conversion plants. The CAD program described could be...

194

Microprocessors: Laboratory Simulation of Industrial Control Applications.  

ERIC Educational Resources Information Center

Describes a course to make technical managers more aware of computer technology and how data loggers, programmable controllers, and larger computer systems interact in a hierarchical configuration of manufacturing process control. (SK)

Gedeon, David V.

1981-01-01

195

Rotorcraft flying qualities improvement using advanced control  

NASA Technical Reports Server (NTRS)

We report on recent experience gained when a multivariable helicopter flight control law was tested on the Large Motion Simulator (LMS) at DRA Bedford. This was part of a study into the application of multivariable control theory to the design of full-authority flight control systems for high-performance helicopters. In this paper, we present some of the results that were obtained during the piloted simulation trial and from subsequent off-line simulation and analysis. The performance provided by the control law led to level 1 handling quality ratings for almost all of the mission task elements assessed, both during the real-time and off-line analysis.

Walker, D.; Postlethwaite, I.; Howitt, J.; Foster, N.

1993-01-01

196

Quality control algorithms for rainfall measurements  

NASA Astrophysics Data System (ADS)

One of the basic requirements for a scientific use of rain data from raingauges, ground and space radars is data quality control. Rain data could be used more intensively in many fields of activity (meteorology, hydrology, etc.), if the achievable data quality could be improved. This depends on the available data quality delivered by the measuring devices and the data quality enhancement procedures. To get an overview of the existing algorithms a literature review and literature pool have been produced. The diverse algorithms have been evaluated to meet VOLTAIRE objectives and sorted in different groups. To test the chosen algorithms an algorithm pool has been established, where the software is collected. A large part of this work presented here is implemented in the scope of the EU-project VOLTAIRE ( Validati on of mu ltisensors precipit ation fields and numerical modeling in Mediter ran ean test sites).

Golz, Claudia; Einfalt, Thomas; Gabella, Marco; Germann, Urs

2005-09-01

197

Practical risk-adjusted quality control charts for infection control  

Microsoft Academic Search

Background:Control chart methodology has been widely touted for monitoring and improving quality in the health care setting. P charts and U charts are frequently recommended for rate and ratio statistics, but their practical value in infection control may be limited because they (1) are not risk-adjusted, and (2) perform poorly with small denominators. The Standardized Infection Ratio is a statistic

Tracy L. Gustafson

2000-01-01

198

Internal quality assurance in a clinical virology laboratory. I. Internal quality assessment.  

PubMed Central

AIMS--In April 1991 an internal quality assessment scheme (IQAS) was introduced into the virology section of the Clinical Microbiology and Public Health Laboratory, Cambridge. The IQAS was established to identify recurring technical and procedural problems, to check the adequacy of current techniques, and to calculate the frequency of errors. METHODS--Between April 1991 and December 1993, 715 anonymous clinical serum samples were submitted to the laboratory to test 3245 individual procedures of diagnostic viral serology. RESULTS--A total of 485 (14.9%) procedural and 61 (1.9%) technical discrepancies were observed, the technical discrepancies mainly being recorded in complement fixation tests. Twenty two (0.7% of total procedures) of the technical discrepancies were diagnostically significant. CONCLUSIONS--Evaluation criteria developed with the introduction of IQAS to viral serology, and technical and procedural discrepancies are assessed. As yet, IQAS has not been introduced to other sections of the diagnostic virology laboratory (virus isolation, electron microscopy, immunofluorescence, and enzyme linked immunosorbent assays for viral and chlamydial antigens).

Gray, J J; Wreghitt, T G; McKee, T A; McIntyre, P; Roth, C E; Smith, D J; Sutehall, G; Higgins, G; Geraghty, R; Whetstone, R

1995-01-01

199

Outsourcing University Degrees: Implications for Quality Control  

ERIC Educational Resources Information Center

Education institutions worldwide have and continue to seek opportunities to spread their offerings abroad. While the provision of courses to students located overseas through partner institutions has many advantages, it raises questions about quality control that are not as applicable to other forms of international education. This paper uses a…

Edwards, Julie; Crosling, Glenda; Edwards, Ron

2010-01-01

200

Timing control improves seabed survey data quality  

Microsoft Academic Search

Seateam has completed development of and field-proven the Dolphin data acquisition and timing system for high-density surveys offshore. The Dolphin project was initiated to improve quality control of survey sensor data and ensure time synchronization, thus leading to faster turnaround of seabed terrain information. Data received from survey sensors is asynchronous, so the system must provide for data correlation. This

1996-01-01

201

Application of Quality Control to Resistance Welding  

Microsoft Academic Search

This paper describes a system of quality control of resistance welding that has been used successfully for the past few years equipment. Standard samples of material identical with production parts are periodically inserted in the welding machine and welded without disturbing the settings and then tested to destruction in a torsion device. The diameter, torque, and angle of twist at

L. S. Hobson; R. S. Inglis; R. P. McCants

1945-01-01

202

A Statistical Method for Software Quality Control  

Microsoft Academic Search

This paper proposes a statistical method that can be used to monitor, control, and predict the quality (measured in terms of the failure intensity) of a software system being tested. The method consists of three steps: estimation of the failure intensity (failures per unit of execution time) based on groups of failures, fitting the logarithmic Poisson model to the estimated

Kazuhira Okumoto

1985-01-01

203

A Comparison of dispersion quality control charts  

Microsoft Academic Search

The problem of detecting shifts in the process variability has not received as much attention as that of detecting shifts in the process mean of continuous production processes, even though it is important in the context of quality control. We examine and compare shewhart s (1931) and Page s (1963) procedures for detecting shifts in variability based on the sample

Kwami Tuprah; Matoteng Ncube

1987-01-01

204

The Institutional Quality Control Handbook. Winter 1984.  

ERIC Educational Resources Information Center

A manual of quality control (QC) techniques is presented for financial aid and fiscal administrators. Steps for establishing, designing, implementing, and evaluating a QC program are outlined including the following: obtaining institutional commitments; developing the QC team; determining priorities for development; determining functions to be…

Office of Student Financial Assistance (ED), Washington, DC.

205

Probabilistic modelling for software quality control  

Microsoft Academic Search

As is clear to any user of software, quality control of software has not reached the same levels of sophistication as it has with traditional manufacturing. In this paper we argue that this is because insufficient thought is being given to the methods of reasoning under uncertainty that are appropriate to this domain. We then describe how we have built

Norman Fenton; Paul Krause; Martin Neil

2002-01-01

206

Quality assurance practices in Europe: a survey of molecular genetic testing laboratories  

PubMed Central

In the 2000s, a number of initiatives were taken internationally to improve quality in genetic testing services. To contribute to and update the limited literature available related to this topic, we surveyed 910 human molecular genetic testing laboratories, of which 291 (32%) from 29 European countries responded. The majority of laboratories were in the public sector (81%), affiliated with a university hospital (60%). Only a minority of laboratories was accredited (23%), and 26% was certified. A total of 22% of laboratories did not participate in external quality assessment (EQA) and 28% did not use reference materials (RMs). The main motivations given for accreditation were to improve laboratory profile (85%) and national recognition (84%). Nearly all respondents (95%) would prefer working in an accredited laboratory. In accredited laboratories, participation in EQA (P<0.0001), use of RMs (P=0.0014) and availability of continuous education (CE) on medical/scientific subjects (P=0.023), specific tasks (P=0.0018), and quality assurance (P<0.0001) were significantly higher than in non-accredited laboratories. Non-accredited laboratories expect higher restriction of development of new techniques (P=0.023) and improvement of work satisfaction (P=0.0002) than accredited laboratories. By using a quality implementation score (QIS), we showed that accredited laboratories (average score 92) comply better than certified laboratories (average score 69, P<0.001), and certified laboratories better than other laboratories (average score 44, P<0.001), with regard to the implementation of quality indicators. We conclude that quality practices vary widely in European genetic testing laboratories. This leads to a potentially dangerous situation in which the quality of genetic testing is not consistently assured.

Berwouts, Sarah; Fanning, Katrina; Morris, Michael A; Barton, David E; Dequeker, Elisabeth

2012-01-01

207

Statistical quality control through overall vibration analysis  

NASA Astrophysics Data System (ADS)

The present study introduces the concept of statistical quality control in automotive wheel bearings manufacturing processes. Defects on products under analysis can have a direct influence on passengers' safety and comfort. At present, the use of vibration analysis on machine tools for quality control purposes is not very extensive in manufacturing facilities. Noise and vibration are common quality problems in bearings. These failure modes likely occur under certain operating conditions and do not require high vibration amplitudes but relate to certain vibration frequencies. The vibration frequencies are affected by the type of surface problems (chattering) of ball races that are generated through grinding processes. The purpose of this paper is to identify grinding process variables that affect the quality of bearings by using statistical principles in the field of machine tools. In addition, an evaluation of the quality results of the finished parts under different combinations of process variables is assessed. This paper intends to establish the foundations to predict the quality of the products through the analysis of self-induced vibrations during the contact between the grinding wheel and the parts. To achieve this goal, the overall self-induced vibration readings under different combinations of process variables are analysed using statistical tools. The analysis of data and design of experiments follows a classical approach, considering all potential interactions between variables. The analysis of data is conducted through analysis of variance (ANOVA) for data sets that meet normality and homoscedasticity criteria. This paper utilizes different statistical tools to support the conclusions such as chi squared, Shapiro-Wilks, symmetry, Kurtosis, Cochran, Hartlett, and Hartley and Krushal-Wallis. The analysis presented is the starting point to extend the use of predictive techniques (vibration analysis) for quality control. This paper demonstrates the existence of predictive variables (high-frequency vibration displacements) that are sensible to the processes setup and the quality of the products obtained. Based on the result of this overall vibration analysis, a second paper will analyse self-induced vibration spectrums in order to define limit vibration bands, controllable every cycle or connected to permanent vibration-monitoring systems able to adjust sensible process variables identified by ANOVA, once the vibration readings exceed established quality limits.

Carnero, M. a. Carmen; González-Palma, Rafael; Almorza, David; Mayorga, Pedro; López-Escobar, Carlos

2010-05-01

208

The Good, the Bad, and the Unknown: Quality of Clinical Laboratories in Kampala, Uganda  

PubMed Central

Background Clinical laboratories are crucial in addressing the high rates of communicable and non-communicable diseases seen in sub-Saharan Africa (SSA). However, the most basic information, such as the number and quality of clinical laboratories in SSA, is not available. The objective of this study was to create a practical method for obtaining this information in SSA towns and cities using an initial survey in Kampala, Uganda. Methods Kampala city was divided into 5 partially-overlapping regions. Each region was assigned to 2–3 surveyors who identified and surveyed laboratories in their respective regions; in person and on foot. A modified version of the World Health Organization - African Region (WHO/AFRO) Laboratory Strengthening Checklist was used to obtain baseline measures of quality for all clinical laboratories within Kampala city. The surveyors also measured other attributes of each laboratory, such as their affiliation (government, private etc), designation (national hospital, district hospital, standalone etc), staff numbers, and type of staff. Results The survey team identified and surveyed 954 laboratories in Kampala city. 96% of laboratories were private. Only 45 (5%) of the laboratories met or surpassed the lowest quality standards defined by the WHO/AFRO-derived laboratory strengthening tool (1-star). These 45 higher-quality laboratories were, on average, larger and had a higher number of laboratory-specific staff (technologists, phlebotomists etc) than the other 909 laboratories. 688 (72%) of the 954 laboratories were not registered with the Ministry of Health (MoH). Conclusions This comprehensive evaluation of the number, scope, and quality of clinical laboratories in Kampala is the first published survey of its kind in sub-Saharan Africa. The survey findings demonstrated that laboratories in Kampala that had qualified personnel and those that had higher testing volumes, tended to be of higher-quality.

Elbireer, Ali M.; Jackson, J. Brooks; Sendagire, Hakim; Opio, Alex; Bagenda, Danstan; Amukele, Timothy K.

2013-01-01

209

Guidelines to implement quality management systems in microbiology laboratories for tissue banking.  

PubMed

Human tissues for implants are a biomedical product that is being used more frequently by many medical disciplines. There are infections in the patients related to the implanted tissues. The early detection of infections transmitted by blood and the microbiological study of tissues before their clinical use are strategies in tissue banks to prevent these situations. This work sought to contribute to establish the bases for the operation of a laboratory applied to the microbiological quality control of tissues. Based on classical microbiological principles, we defined the operation of microbiological control and tissues sterilization since 2003. We determine lists of acceptable microorganisms for every tissue, criteria for the interpretation of results, and a diagnostic algorithm of microbiological quality. We observed that the circumstances of donor death can be a determinant of the quality. The environment and the operator should be investigated as probable sources of contamination in outbreaks. The criteria of work based on a solid methodology must help to avoid the transmission of infections between donor and recipient. This is a critical point in the quality management of a tissue bank. PMID:19857776

Vicentino, W; Rodríguez, G; Saldías, M; Alvarez, I

2009-10-01

210

Field Methods and Quality-Assurance Plan for Quality-of-Water Activities, U.S. Geological Survey, Idaho National Laboratory, Idaho  

USGS Publications Warehouse

Water-quality activities conducted by the staff of the U.S. Geological Survey (USGS) Idaho National Laboratory (INL) Project Office coincide with the USGS mission of appraising the quantity and quality of the Nation's water resources. The activities are conducted in cooperation with the U.S. Department of Energy's (DOE) Idaho Operations Office. Results of the water-quality investigations are presented in various USGS publications or in refereed scientific journals. The results of the studies are highly regarded, and they are used with confidence by researchers, regulatory and managerial agencies, and interested civic groups. In its broadest sense, quality assurance refers to doing the job right the first time. It includes the functions of planning for products, review and acceptance of the products, and an audit designed to evaluate the system that produces the products. Quality control and quality assurance differ in that quality control ensures that things are done correctly given the 'state-of-the-art' technology, and quality assurance ensures that quality control is maintained within specified limits.

Knobel, LeRoy L.; Tucker, Betty J.; Rousseau, Joseph P.

2008-01-01

211

Quality assurance testing of an explosives trace analysis laboratory--further improvements.  

PubMed

The Forensic Explosives Laboratory (FEL) operates within the Defence Science and Technology Laboratory (DSTL) which is part of the UK Government Ministry of Defence (MOD). The FEL provides support and advice to the Home Office and UK police forces on matters relating to the criminal misuse of explosives. During 1989 the FEL established a weekly quality assurance testing regime in its explosives trace analysis laboratory. The purpose of the regime is to prevent the accumulation of explosives traces within the laboratory at levels that could, if other precautions failed, result in the contamination of samples and controls. Designated areas within the laboratory are swabbed using cotton wool swabs moistened with ethanol water mixture, in equal amounts. The swabs are then extracted, cleaned up and analyzed using Gas Chromatographs with Thermal Energy Analyzer detectors. This paper follows on from a previous published paper describing the regime and summarizing subsequent results from approximately 6 years of tests. Lessons learned and improvements made over the period are also discussed. Monitoring samples taken from surfaces within the trace laboratories and trace vehicle examination bay have, with few exceptions, revealed only low levels of contamination, predominantly of RDX. Analysis of the control swabs, processed alongside the monitoring swabs, has demonstrated that in this environment the risk of forensic sample contamination, assuming all the relevant anti-contamination procedures have been followed, is so small that it is considered to be negligible. The monitoring regime has also been valuable in assessing the process of continuous improvement, allowing sources of contamination transfer into the trace areas to be identified and eliminated. PMID:17524053

Crowson, Andrew; Doyle, Sean P; Todd, Clifford C; Watson, Stuart; Zolnhofer, Nicola

2007-07-01

212

Combined Shewhart-cusum control chart for improved quality control in clinical chemistry.  

PubMed

We describe the adaptation of the decision limit cumulative sum method (cusum) to internal quality control in clinical chemistry. With the decision limit method, the cusum is interpreted against a numerical limit, rather than by use of a V-mask. The method can be readily implemented in computerized quality-control systems or manually on controls charts. We emphasize the manual application here and demonstrate how the technique can be implemented on existing Shewhart or Levey-Jennings control charts. This permits both cusum and Shewhart control rules to be used simultaneously on a single control chart and also minimizes the data calculations necessary for the cusum method. Computer simulation studies are used to determine the performance characteristics of several different cusum rules, alone and in combination with a Shewhart rule. These studies indicate that improvements in existing quality-control systems should be possible by addition of this simple cusum method and by use of a combined Shewhart-cusum control chart. This should be particularly advantageous when introducing the cusum method in laboratories with manual quality-control systems. PMID:902415

Westgard, J O; Groth, T; Aronsson, T; de Verdier, C H

1977-10-01

213

Quality control: Quality control at the plasma membrane: One mechanism does not fit all.  

PubMed

The plasma membrane quality control system of eukaryotic cells is able to recognize and degrade damaged cell surface proteins. Recent studies have identified two mechanisms involved in the recognition of unfolded transmembrane proteins. One system uses chaperones to detect unfolded cytoplasmic domains of transmembrane proteins, whereas the second mechanism relies on an internal quality control system of the protein, which can trigger degradation when the protein deviates from the folded state. Both quality control mechanisms are key to prevent proteotoxic effects at the cell surface and to ensure cell integrity. PMID:24733583

Babst, Markus

2014-04-14

214

Practicing Quality Control in a Bioanalytical Experiment  

NASA Astrophysics Data System (ADS)

The quality of analytical results frequently requires assessment, which has fostered treatment of this subject in a host of chemical books for students. Accordingly, new experiments need to be devised in order to help students adapt to it. This paper presents a straightforward exercise to demonstrate how quality control and the analysis of variance technique are implemented in practice. The exercise also is attractive because the analyte (chlorophyl) is determined in real samples (plants) that students can collect by themselves. In this way, they can realize the significance of sampling and learn how to do it properly.

Marcos, Juliana; Ríos, Angel; Valcárcel, Miguel

1995-10-01

215

Quality control procedures at Euskalmet data center  

NASA Astrophysics Data System (ADS)

The Basque Country Mesonet measures more than 130 000 observations daily from its 85 Automatic Weather Stations (AWS). It becomes clear that automated software is an indispensable tool for quality assurance (QA) of this mesoscale surface observing network. This work describes a set of experimental semi-automatic quality control (QC) routines that is applied at Euskalmet data center. It has paid special attention to level validation design and associated flags, as well as to the system outputs, which are used by meteorologist and maintenance staff.

Hernández, R.; Maruri, M.; Otxoa de Alda, K.; Egaña, J.; Gaztelumendi, S.

2012-06-01

216

Quality and Control of Water Vapor Winds  

NASA Technical Reports Server (NTRS)

Water vapor imagery from the geostationary satellites such as GOES, Meteosat, and GMS provides synoptic views of dynamical events on a continual basis. Because the imagery represents a non-linear combination of mid- and upper-tropospheric thermodynamic parameters (three-dimensional variations in temperature and humidity), video loops of these image products provide enlightening views of regional flow fields, the movement of tropical and extratropical storm systems, the transfer of moisture between hemispheres and from the tropics to the mid- latitudes, and the dominance of high pressure systems over particular regions of the Earth. Despite the obvious larger scale features, the water vapor imagery contains significant image variability down to the single 8 km GOES pixel. These features can be quantitatively identified and tracked from one time to the next using various image processing techniques. Merrill et al. (1991), Hayden and Schmidt (1992), and Laurent (1993) have documented the operational procedures and capabilities of NOAA and ESOC to produce cloud and water vapor winds. These techniques employ standard correlation and template matching approaches to wind tracking and use qualitative and quantitative procedures to eliminate bad wind vectors from the wind data set. Techniques have also been developed to improve the quality of the operational winds though robust editing procedures (Hayden and Veldon 1991). These quality and control approaches have limitations, are often subjective, and constrain wind variability to be consistent with model derived wind fields. This paper describes research focused on the refinement of objective quality and control parameters for water vapor wind vector data sets. New quality and control measures are developed and employed to provide a more robust wind data set for climate analysis, data assimilation studies, as well as operational weather forecasting. The parameters are applicable to cloud-tracked winds as well with minor modifications. The improvement in winds through use of these new quality and control parameters is measured without the use of rawinsonde or modeled wind field data and compared with other approaches.

Jedlovec, Gary J.; Atkinson, Robert J.

1996-01-01

217

[Discuss on crispness to quality control of calcined drugs].  

PubMed

At present, the production and quality control of calcined drugs were lack of corresponding quantitative indicators, and only relied on traditional empirical control, thus it was susceptible to subjective factors, and the qualities of calcined drugs were affected. This paper analyzes the current status of the quality control of calcined drugs, the traditional quality requirements, modern quality controls and evaluation methods of calcined drugs were systematically summarized. Take the example for pyritum, a quality control method which reflects crispness of calcined drugs with density variety was investigated, and the feasibility of its application was discussed, therefore a new quantitative indicator for quality control of calcined drugs was supplied. PMID:20506833

Wang, Hongbin; Xiao, Jieming; Cai, Hao; Cai, Baochang

2010-03-01

218

Development of an access-by-the-Internet control laboratory  

Microsoft Academic Search

The paper reports on the on-going development of a control laboratory that can be accessed remotely through the Internet. This laboratory currently consists of a few sets of signal generator\\/oscilloscope experiments, five Feedback 33-002 Analogue Fundamentals Trainers and five Feedback 33-003 Digital Servo Fundamentals Trainers. The key tasks involved in the development of this laboratory include the interface between the

J. Fisher; W. S. Hoye; J. Koehler; R. Lian; Zongli Lin

2001-01-01

219

42 CFR 84.41 - Quality control plans; contents.  

Code of Federal Regulations, 2013 CFR

...the Institute, where the quality control plan provisions for raw material...inspections are adequate to ensure control of finished article quality...section are approved under OMB control number...

2013-10-01

220

42 CFR 84.41 - Quality control plans; contents.  

Code of Federal Regulations, 2012 CFR

...including: (1) Requirements for the production of quality data and the use of quality control records; (2) Control of engineering drawings, documentations, and changes; (3) Control and calibration of measuring and test equipment; (4)...

2012-10-01

221

Dynamic process quality control system under networked manufacturing  

Microsoft Academic Search

To solve problems concerning the process quality control of networked manufacturing enterprise, a dynamic process quality control mode oriented to networked manufacturing, which integrated quality prevention, analysis, diagnosis and adjustment, and corresponding functional modules and framework were all put forward. This mode dealt mainly with constructing and running dynamic quality control system, integrated several enabling technologies such as the theory

Jiang Xingyu; Yang Jianyu; Tang Liang; Wang Wanshan

2008-01-01

222

Daily quality control for breast tomosynthesis  

NASA Astrophysics Data System (ADS)

Breast tomosynthesis is an imaging modality that recently became available for breast examination. For conventional projection mammography quality control procedures are well described. For breast tomosynthesis, on the other hand, such procedures have not yet been established. In this paper we propose a simple method and phantom for daily quality control (DQC). With DQC image quality problems arising after acceptance of the system should be detected. Therefore, the DQC procedure needs to monitor the stability of the most critical components of the system over time. For breast tomosynthesis we assume that the most critical items are the image receptor, X-ray tube and the tomosynthesis motion. In the proposed procedure the image receptor homogeneity and system stability are evaluated using an image of a homogeneous block of PMMA. The z-resolution is assumed to be dependent on the tomosynthesis motion. To monitor this motion the nominal z-resolution using the slice sensitive profile is measured. Shading artefacts that arise due to objects with high attenuation are also typical for tomosynthesis systems. Analysing those artefacts may provide additional information about the tomosynthesis motion. The proposed DQC procedure has been evaluated on two different breast tomosynthesis systems: A multi slit scanning system and a system using a stationary a-Se detector. Preliminary results indicate that the proposed method is useful for DQC, although some minor changes to the phantoms are advised. To verify that this method detects image quality problems sufficiently, more experience with different DBT systems, over longer periods of time are needed.

Bouwman, R. W.; Visser, R.; Young, K. C.; Dance, D. R.; Lazzari, B.; van der Burght, R.; Heid, P.; van Engen, R. E.

2010-03-01

223

Ball on beam on roller: a new control laboratory device  

Microsoft Academic Search

This paper describes a new control laboratory device, named ball on beam on roller. The control objective is to govern the position of a ball on the beam, the latter freely resting on the driven roller. The angular attitude of the beam is varied by shifting the lateral position of the beam, through control of the roller's angular acceleration. The

S. Sridharan; G. Sridharan

2002-01-01

224

Quality control of VLT-VIMOS data  

NASA Astrophysics Data System (ADS)

VIMOS is the Visible Multi-Object Spectrograph mounted at the Nasmyth focus of the 8.2m Melipal (UT3) telescope of the ESO Very Large Telescope. VIMOS operates with four channels in three observing modes: imaging, multi-object spectroscopy (MOS), and integral field spectroscopy. VIMOS data are pipeline-processed and quality-checked by the Data Flow Operation group in Garching. The quality check is performed in two steps. The first one is a visual check of each pipeline product that allows the identification of any potential major data problem, such as, for example, a failure in the MOS mask insertion or an over/under exposure. The second step is performed in terms of Quality Control (QC) parameters, which are derived from both raw and processed data to monitor the instrument performance. The evolution in time of the QC parameters is recorded in a publically available database (http://www.eso.org/qc/). The VIMOS QC parameters include, for each of the four VIMOS channels, the bias level, read-out-noise, dark current, gain factor, flat-field and arc-lamps efficiencies, resolution and rms of dispersion, sky flat-field structure, image quality and photometric zeropoints. We describe here some examples of quality checks of VIMOS data.

Sartoretti, Paola; Izzo, Carlo; Palsa, Ralf M.; Marconi, Gianni; Brillant, Stephane; Kissler-Patig, Markus; Bagnulo, Stefano

2004-09-01

225

Mitochondrial quality control in neurodegenerative diseases.  

PubMed

Mutations causing genetic forms of Parkinson's disease or hereditary neuropathies have been recently shown to affect key molecular players involved in the recycling of defective mitochondria, most notably PARKIN, PINK1, Mitofusin 2 or dynein heavy chain. Interestingly, the same pathways are also indirectly targeted by multiple other mutations involved in familial forms of amyotrophic lateral sclerosis, Huntington's disease or Alzheimer's disease. These recent genetic results strongly reinforce the notion that defective mitochondrial physiology might cause neurodegeneration. Mitochondrial dysfunction has however been observed in virtually every neurodegenerative disease and appears not restricted to the most vulnerable neuronal populations affected by a given disease. Thus, the mechanisms linking defective mitochondrial quality control to death of selective neuronal populations remain to be identified. This review provides an update on the most recent literature on mitochondrial quality control and its impairment during neurodegenerative diseases. PMID:23958438

Dupuis, Luc

2014-05-01

226

Quality Control Mechanisms During Ribosome Maturation  

PubMed Central

Protein synthesis on ribosomes is carefully quality controlled to ensure the faithful transmission of genetic information from mRNA to protein. Many of these mechanisms rely on communication between distant sites on the ribosomes, and thus on the integrity of the ribosome structure. Furthermore, haploinsufficiency of ribosomal proteins, which increases the chances of forming incompletely assembled ribosomes, can predispose to cancer. Finally, release of inactive ribosomes into the translating pool will lead to their degradation together with the degradation of the bound mRNA. Together, these findings suggest that quality control mechanisms must be in place to survey nascent ribosomes and ensure their functionality. This review gives an account of these mechanisms as currently known.

Karbstein, Katrin

2013-01-01

227

Technical Justification for Radiation Controls at an Environmental Laboratory  

SciTech Connect

This paper describes the technical approach used to establish radiation protection controls over incoming radioactive materials to an environmental measurements laboratory at the Hanford Site. Conditions that would trigger internal dosimetry, posting.

DUPAQUIER, J.C.

2000-07-01

228

Water Quality Assessment and Control in Bulgaria  

Microsoft Academic Search

An analysis of the Bulgarian legislation in the field of water and wastewater management harmonized with the European Union's\\u000a one during the last decade, regarding laws, directives, standards, etc. and its implementation is made. The results of the\\u000a analysis show that water and wastewater quality assessment and control in Bulgaria are performed according to the legislation.\\u000a Some modifications of the

Elitza Angelova

229

Towards quality control of food using terahertz  

NASA Astrophysics Data System (ADS)

Terahertz radiation or T-rays, show promise in quality control of food products. As T-rays are inherently sensitive to water, they are very suitable for moisture detection. This proves to be a valuable asset in detecting the moisture content of dried food, a critical area for some products. As T-rays are transparent to plastics, food additives can also be probed through the packaging, providing checks against a manufacturer's claims, such as the presence of certain substances in foods.

Ung, B. S.-Y.; Fischer, B. M.; Ng, B. W.-H.; Abbott, D.

2007-12-01

230

Antimicrobial susceptibility testing of Streptococcus pneumoniae and Haemophilus influenzae --internal quality control as a quality tool on a national level.  

PubMed

Knowledge of the quality and conformity of antimicrobial resistance data is important for comparing resistance rates regionally and over time. In this study, we have evaluated these features of the Finnish national susceptibility surveillance data for two respiratory tract pathogens, Streptococcus pneumoniae and Haemophilus influenzae. For this purpose internal quality control results for two isolates (S. pneumoniae ATCC 49619 and H. influenzae ATCC 49247) were analyzed from 21 clinical microbiology laboratories over a 3-year period. The results show that standardization of the susceptibility testing methods has proceeded well. The number of protocols used for susceptibility testing has declined (from seventeen methods to two with S. pneumoniae and from eleven to three with H. influenzae) and the reproducibility is good. Nevertheless, we noticed that a few laboratories test and report susceptibility results without defined break-points and even include antimicrobials with questionable therapeutic effect. Another non-compliance with the standard was a lack of a regular control system to verify the attainment of the intended quality of results in some laboratories. Interlaboratory analysis of quality control results is a good way to evaluate the quality and conformity of national resistance data. Finnish laboratories have produced very reproducible and accurate susceptibility results in the pre-EUCAST period, which ended in 2011. PMID:23163534

Kärpänoja, Pauliina; Nissinen, Antti; Huovinen, Pentti; Sarkkinen, Hannu

2013-06-01

231

Integrated quality control: implementation and validation of instrument function checks and procedural controls for a cartridge-based point-of-care system for critical care analysis.  

PubMed

In this article, the process used to develop and validate an integrated quality-control system for a cartridge-based, point-of-care system for critical care analysis is outlined. Application of risk management principles has resulted in a quality control system using a combination of statistical quality control with onboard reference solutions and failure pattern recognition used to flag common failure modes during the analytical phase of the testing process. A combination of traditional external quality control, integrated quality control to monitor ongoing instrument functionality, operator training, and other laboratory-implemented monitors is most effective in controlling known failure modes during the testing process. PMID:23331731

D'Orazio, Paul; Mansouri, Sohrab

2013-03-01

232

[Software for illustrating a cost-quality balance carried out by clinical laboratory practice].  

PubMed

We have no proper reference indicating the quality of clinical laboratory practice, which should clearly illustrates that better medical tests require more expenses. Japanese Society of Laboratory Medicine was concerned about recent difficult medical economy and issued a committee report proposing a guideline to evaluate the good laboratory practice. According to the guideline, we developed software that illustrate a cost-quality balance carried out by clinical laboratory practice. We encountered a number of controversial problems, for example, how to measure and weight each quality-related factor, how to calculate costs of a laboratory test and how to consider characteristics of a clinical laboratory. Consequently we finished only prototype software within the given period and the budget. In this paper, software implementation of the guideline and the above-mentioned problems are summarized. Aiming to stimulate these discussions, the operative software will be put on the Society's homepage for trial PMID:20963949

Nishibori, Masahiro; Asayama, Hitoshi; Kimura, Satoshi; Takagi, Yasushi; Hagihara, Michio; Fujiwara, Mutsunori; Yoneyama, Akiko; Watanabe, Takashi

2010-09-01

233

Remote-controlled photonics laboratories for distance learning  

NASA Astrophysics Data System (ADS)

At Queensborough Community College, with the support of the National Science Foundation (Advanced Technological Education grant award #DUE - 9752061), we have addressed the issues of distance learning and laboratories and are adapting courses for our Laser and Fiber-Optics Technology Program for distance learning. The 'problem' of the laboratory is solved by remote-controlled laboratory equipment. We have completed the work on course materials in physical optics, lasers and fiber optics. Course materials include interactive multimedia textbooks and laboratory manuals along with the remote-controlled laboratory exercises. The remote-controlled exercises are 'real' experiments with 'real' data as opposed to simulations. The real nature of the exercises allows for the unexpected, which occurs in any laboratory situation. Remote-controlled laboratory exercises include interferometry, diffraction, polarization, acousto-optics, electro-optics, second harmonic generation, Q-switching, modelocking, thermal lensing, diode laser characteristics, laser principles, optical time domain reflectometry, coupling losses, wave division multiplexing and characteristics of fiber optic switches and couplers. As course materials were developed they were tested at a remote site, Suffolk County Community College.

Lieberman, David H.; Cheung, Tak D.

2002-05-01

234

Sandia National Laboratories, California Air Quality Program: Annual Report.  

National Technical Information Service (NTIS)

The annual program report provides detailed information about all aspects of the SNL/CA Air Quality Program. It functions as supporting documentation to the SNL/CA Environmental Management System Program Manual. The program report describes the activities...

L. P. Gardizi R. Shih

2007-01-01

235

Weight control and restraint of laboratory rats  

NASA Technical Reports Server (NTRS)

The use of restrained and confined rats in some procedures used in combustion toxicology introduces the problems of obtaining rats of the appropriate size for the apparatus, and of identifying any artifacts resulting from the use of restraint alone. Feeding studies indicate that controlled feeding of fast-growing strains such as the Sprague-Dawley can hold rat size essentially constant for significant periods of time. The undesirable aspects are the need to cage the animals individually, with resultant psychological as well as metabolic effects. Restraint studies of slow-growing strains such as the Fischer 344 indicate that denying access to food and water for periods of several hours at a time interrupts normal gain only temporarily.

Hilado, C. J.; Van Breda Kolff, K.

1979-01-01

236

Method of Analysis at the U.S. Geological Survey California Water Science Center, Sacramento Laboratory: Determination of Haloacetic Acid Formation Potential, Method Validation, and Quality-Control Practices.  

National Technical Information Service (NTIS)

An analytical method for the determination of haloacetic acid formation potential of water samples has been developed by the U.S. Geological Survey California Water Science Center, Sacramento Laboratory. The haloacetic acid formation potential is measured...

B. C. Zazzi K. L. Crepeau M. S. Fram B. A. Bergamaschi

2005-01-01

237

Intelligent process quality control system into supply chain  

Microsoft Academic Search

To cope with the challenges of monitoring dynamic and variable quality variation into supply chain, diagnosing the abnormal variation at the right moment, is a difficult problem that a enterprise in supply chain faces in process quality control. An intelligent process quality control mode into supply chain, which integrated quality prevention, analysis, diagnosis and adjustment, and corresponding functional modules and

Shijie Wang; Xingyu Jiang; Yingchun Wang

2009-01-01

238

Infection Control Procedures in Commercial Dental Laboratories in Jordan  

Microsoft Academic Search

The risk of cross-infection in dental clinics and laboratories has attracted the attention of practitioners for the past few years, yet several medical centers have discarded compliance with infection control guidelines, resulting in a non-safe environ- ment for research and medical care. In Jordan, there is lack of known standard infection control programs that are conducted by the Jordanian Dental

Ziad Nawaf Al-Dwairi

239

Providing Quality Laboratories to Long-Distance Educational Programs.  

ERIC Educational Resources Information Center

North Carolina State University (UNC) has been on the forefront of long-distance education by offering a Bachelor of Science in Engineering with a Mechatronics Concentration at its remote campus located at UNC Asheville. The program demonstrates that long-distance laboratories are feasible and should not be a stumbling block to offering…

Gammon, Tammy; Sutton, John

2003-01-01

240

21 CFR 211.22 - Responsibilities of quality control unit.  

Code of Federal Regulations, 2013 CFR

21 Food and Drugs 4 2013-04-01... Responsibilities of quality control unit. 211.22 Section 211.22 Food and Drugs FOOD AND DRUG ADMINISTRATION... Responsibilities of quality control unit. (a) There shall...

2013-04-01

241

Prediction Models are Basis for Rational Air Quality Control  

ERIC Educational Resources Information Center

An air quality control scheme employing meteorological diffusion, time averaging and frequency, and cost-benefit models is discussed. The methods outlined provide a constant feedback system for air quality control. Flow charts and maps are included. (BL)

Daniels, Anders; Bach, Wilfrid

1973-01-01

242

Data quality control in genetic case-control association studies.  

PubMed

This protocol details the steps for data quality assessment and control that are typically carried out during case-control association studies. The steps described involve the identification and removal of DNA samples and markers that introduce bias. These critical steps are paramount to the success of a case-control study and are necessary before statistically testing for association. We describe how to use PLINK, a tool for handling SNP data, to perform assessments of failure rate per individual and per SNP and to assess the degree of relatedness between individuals. We also detail other quality-control procedures, including the use of SMARTPCA software for the identification of ancestral outliers. These platforms were selected because they are user-friendly, widely used and computationally efficient. Steps needed to detect and establish a disease association using case-control data are not discussed here. Issues concerning study design and marker selection in case-control studies have been discussed in our earlier protocols. This protocol, which is routinely used in our labs, should take approximately 8 h to complete. PMID:21085122

Anderson, Carl A; Pettersson, Fredrik H; Clarke, Geraldine M; Cardon, Lon R; Morris, Andrew P; Zondervan, Krina T

2010-09-01

243

Data quality control in genetic case-control association studies  

PubMed Central

This protocol details the data quality assessment and control steps that are typically carried out during case-control association studies. The steps described involve the identification and removal of DNA samples and markers that introduce bias to the study. These critical steps are paramount to the success of a case-control study and are necessary before statistically testing for association. We describe how to use PLINK, a tool for handling SNP data, to carry out assessments of failure rate per-individual and per-SNP and to assess the degree of relatedness between individuals. We also detail other quality control procedures, including the use of SMARTPCA for the identification of ancestral outliers. These platforms were selected because they are user-friendly, widely used, and computationally efficient. Steps needed to detect and establish a disease association using case-control data are not discussed, as these are provided in a further protocol in the series. Issues concerning the study design and marker selection in case-control studies have been discussed in our earlier protocols. The protocol should take approximately 8 hours to complete.

Anderson, Carl A.; Pettersson, Fredrik H; Clarke, Geraldine M; Cardon, Lon R; Morris, Andrew P.; Zondervan, Krina T.

2010-01-01

244

Videoteletraining Delivery of a Quality Assurance Course with a Computer Laboratory.  

National Technical Information Service (NTIS)

A Quality Assurance (QA) course containing a student computer laboratory was delivered by videoteletraining (VTT). Two primary treatment groups were compared during four class convenings with a total of 100 students: (1) a VTT local classroom with an inst...

C. D. Wetzel H. L. Pugh N. VanMatre S. W. Parchman

1996-01-01

245

Medical Services: Department of Defense Veterinary/Medical Laboratory Food Safety and Quality Assurance Program.  

National Technical Information Service (NTIS)

This consolidated regulation on Food Safety Evaluation Programs prescribes: policies and functions of the veterinary laboratory service; and specialized requirements and microbiological standards for answering food safety and quality assurance for potenti...

1995-01-01

246

Application of Traditional Clinical Pathology Quality Control Techniques to Molecular Pathology  

PubMed Central

Many molecular diagnostic laboratories have evolved from research laboratories, initially performing low numbers of homebrew assays, but many laboratories now perform more kit-based assays, with ever increasing test volumes. One such assay is assessment of bone marrow transplantation engraftment. Allogeneic bone marrow transplantation is performed primarily in the treatment of hematological malignancies. Monitoring of engraftment was traditionally evaluated using minisatellites (variable number tandem repeats) and Southern blotting, but most laboratories now use Food and Drug Administration-cleared microsatellite (short tandem repeats) kits to assess the extent of engraftment. With the increase in equipment reliability, the use of kit-based assays, and the desire to provide the highest quality clinical data, we began applying traditional clinical pathology quality control tools to the molecular diagnostics laboratory. In this study, we demonstrate this approach using a microsatellite-based bone marrow engraftment assay. We analyzed control samples (pure and mixed) for two different microsatellites to establish quality control parameters and constructed Levey-Jennings charts to monitor both the precision and accuracy of this assay. By incorporating these tools into an overall quality assurance program, a laboratory can identify systematic errors and perform corrective actions before actual assay failure, thereby improving the quality of patient care.

Liang, Shu-Ling; Lin, Ming-Tseh; Hafez, Michael J.; Gocke, Christopher D.; Murphy, Kathleen M.; Sokoll, Lori J.; Eshleman, James R.

2008-01-01

247

Application of traditional clinical pathology quality control techniques to molecular pathology.  

PubMed

Many molecular diagnostic laboratories have evolved from research laboratories, initially performing low numbers of homebrew assays, but many laboratories now perform more kit-based assays, with ever increasing test volumes. One such assay is assessment of bone marrow transplantation engraftment. Allogeneic bone marrow transplantation is performed primarily in the treatment of hematological malignancies. Monitoring of engraftment was traditionally evaluated using minisatellites (variable number tandem repeats) and Southern blotting, but most laboratories now use Food and Drug Administration-cleared microsatellite (short tandem repeats) kits to assess the extent of engraftment. With the increase in equipment reliability, the use of kit-based assays, and the desire to provide the highest quality clinical data, we began applying traditional clinical pathology quality control tools to the molecular diagnostics laboratory. In this study, we demonstrate this approach using a microsatellite-based bone marrow engraftment assay. We analyzed control samples (pure and mixed) for two different microsatellites to establish quality control parameters and constructed Levey-Jennings charts to monitor both the precision and accuracy of this assay. By incorporating these tools into an overall quality assurance program, a laboratory can identify systematic errors and perform corrective actions before actual assay failure, thereby improving the quality of patient care. PMID:18258922

Liang, Shu-Ling; Lin, Ming-Tseh; Hafez, Michael J; Gocke, Christopher D; Murphy, Kathleen M; Sokoll, Lori J; Eshleman, James R

2008-03-01

248

Training for Federal Quality Control Review. Instructor's Guide.  

ERIC Educational Resources Information Center

The instructor's guide is a companion document to the training manual, Training for Federal Quality Control Review. It is designed to aid regional training personnel in teaching the contents of the training manual to Federal Quality Control re-reviewers. This guide may also be used to train State staff in the quality control system and review…

Social and Rehabilitation Service (DHEW), Washington, DC. Office of Quality Control Management.

249

Guidance on Quality Control for Inspection/Maintenance Programs.  

National Technical Information Service (NTIS)

This report provides guidance on the areas that need to be addressed in a quality control plan and on recommended quality control procedures that can be used in the quality control program. This guidance is important because of the emissions performance w...

1982-01-01

250

A Method Product Quality Control between Enterprises and its Implementation  

Microsoft Academic Search

Along with the intensification of global competition and the complexity of manufacturing products, the cooperation among enterprises becomes more closely, and the range of quality control extends from internal to the external enterprises. To the demand of product quality control among enterprises, based on holon theory, the product quality control holonic structure for extended enterprises is constructed by the similarity

Jie Tian; Jianxin Lv

2010-01-01

251

Product Quality Control Method for Extended Enterprises Based on Holonic  

Microsoft Academic Search

Based on holons theory, the product quality control holonic structure for extended enterprises is constructed by the similarity characteristic of quality control function extended enterprises. In the structure, the quality control holons that has autonomy and cooperation ability are established, and by the analysis of holon cooperation operation, by means of the definition and description the cooperation relations among holons,

Xiaolin Xu

2009-01-01

252

A technique for standardization and quality control of subjective sperm motility assessments in semen analysis  

Microsoft Academic Search

Objective: To establish a quality control method to monitor and eventually to standardize the subjective assessment of sperm motility in conventional semen analysis.Design: Quality control study running over 2 years.Setting: University infertility clinic and andrology laboratory.Patient(s): Randomly chosen patients attending the clinic.Main Outcome Measure(s): Conventional semen analysis with sperm motility assessed by grading according to the World Health Organization (WHO)

Ching-Hei Yeung; Trevor G. Cooper; Eberhard Nieschlag

1997-01-01

253

Integrated quality control architecture for multistage machining processes  

NASA Astrophysics Data System (ADS)

To solve problems concerning the process quality prediction control for the multistage machining processes, a integrated quality control architecture is proposed in this paper. First, a hierarchical multiple criteria decision model is established for the key process and the weight matrix method stratified is discussed. Predictive control of the manufacturing quality is not just for on-site monitoring and control layer, control layer in the enterprise, remote monitoring level of quality exists a variety of target predictive control demand, therefore, based on XML to achieve a unified description of manufacturing quality information, and in different source of quality information between agencies to achieve the transfer and sharing. This will predict complex global quality control, analysis and diagnosis data to lay a good foundation to achieve a more practical, open and standardized manufacturing quality with higher levels of information integration system.

Yang, Jie; Liu, Guixiong

2010-12-01

254

The World Health Organization African region laboratory accreditation process: improving the quality of laboratory systems in the African region.  

PubMed

Few developing countries have established laboratory quality standards that are affordable and easy to implement and monitor. To address this challenge, the World Health Organization Regional Office for Africa (WHO AFRO) established a stepwise approach, using a 0- to 5-star scale, to the recognition of evolving fulfillment of the ISO 15189 standard rather than pass-fail grading. Laboratories that fail to achieve an assessment score of at least 55% will not be awarded a star ranking. Laboratories that achieve 95% or more will receive a 5-star rating. This stepwise approach acknowledges to laboratories where they stand, supports them with a series of evaluations to use to demonstrate improvement, and recognizes and rewards their progress. WHO AFRO's accreditation process is not intended to replace established ISO 15189 accreditation schemes, but rather to provide an interim pathway to the realization of international laboratory standards. Laboratories that demonstrate outstanding performance in the WHO-AFRO process will be strongly encouraged to enroll in an established ISO 15189 accreditation scheme. We believe that the WHO-AFRO approach for laboratory accreditation is affordable, sustainable, effective, and scalable. PMID:20716795

Gershy-Damet, Guy-Michel; Rotz, Philip; Cross, David; Belabbes, El Hadj; Cham, Fatim; Ndihokubwayo, Jean-Bosco; Fine, Glen; Zeh, Clement; Njukeng, Patrick A; Mboup, Souleymane; Sesse, Daniel E; Messele, Tsehaynesh; Birx, Deborah L; Nkengasong, John N

2010-09-01

255

Water Quality & Pollutant Source Monitoring: Field and Laboratory Procedures. Training Manual.  

ERIC Educational Resources Information Center

This training manual presents material on techniques and instrumentation used to develop data in field monitoring programs and related laboratory operations concerned with water quality and pollution monitoring. Topics include: collection and handling of samples; bacteriological, biological, and chemical field and laboratory methods; field…

Office of Water Program Operations (EPA), Cincinnati, OH. National Training and Operational Technology Center.

256

The operation, quality and costs of a district hospital laboratory service in Malawi  

Microsoft Academic Search

Laboratory services are run down in many low-income countries, severely constraining their input to patient care and disease surveillance. There are few data about the quality and cost of individual components of the laboratory service in poorer countries, yet this information is essential if optimal use is to be made of scarce resources. Staff time, range of tests, workload, and

C. J. F. Mundy; I. Bates; W. Nkhomal; K. Floyd; G. Kadewele; M. Ngwira; A. Khuwi; S. B. Squire; C. F. Gilks

2003-01-01

257

Ubiquitin Receptors and Protein Quality Control  

PubMed Central

Protein quality control (PQC) is essential to intracellular proteostasis and is carried out by sophisticated collaboration between molecular chaperones and targeted protein degradation. The latter is performed by proteasome-mediated degradation, chaperone-mediated autophagy (CMA), and selective macroautophagy, and collectively serve as the final line of defense of PQC. Ubiquitination and subsequently ubiquitin (Ub) receptor proteins (e.g., p62 and Ubiquilins) are important common factors for targeting misfolded proteins to multiple quality control destinies, including the proteasome, lysosomes, and perhaps aggresomes, as well as for triggering mitophagy to remove defective mitochondria. PQC inadequacy, particularly proteasome functional insufficiency, has been shown to participate in cardiac pathogenesis. Tremendous advances have been made in unveiling the changes of PQC in cardiac diseases. However, the investigation into the molecular pathways regulating PQC in cardiac (patho)physiology, including the function of most ubiquitin receptor proteins in the heart, has only recently been initiated. A better understanding of molecular mechanisms governing PQC in cardiac physiology and pathology will undoubtedly provide new insights into cardiac pathogenesis and promote the search for novel therapeutic strategies to more effectively battle heart disease.

Wang, Xuejun; Terpstra, Erin J. M.

2013-01-01

258

Data quality control of ADSN Broadband stations  

NASA Astrophysics Data System (ADS)

In this work we present the analysis of continuous waveform of the Algerian digital seismic network recorded during five years from 2008 to 2013 for twenty broadband stations using the power spectral densities (PSDs) and their corresponding probability density functions (PDFs) algorithm of McNamara, and Buland (2004). ADSN Broadband stations data quality is one main concern and interest of ADSN technical team. Indeed, the quality of the data from broadband stations is continuously controlled in quasi-realtime using "PQLX" (Pascal Quick Look eXtended) software to compute the PDFs and PSDs during the operation of the stations at different frequency range. At each station the level of noise is shown, which we can see diurnal and seasonal variation. From the data analysis, most of the ADSN Broadband stations display good records in the several frequency domains in relation with their site installation. However some of stations near the urban areas could present some noisy disturbances. This led sometimes to generate some ghost events. In the low frequency, some stations could be still influenced by the temperature variations. This long period of records from 2008 to 2013, led us to analyze and control the several stations year by year taking into account the seasons and to know about their work during five years. This analysis is also very important to improve in the future quality of station installation and choose the optimal station design in aim to reduce cultural noise and large fluctuation of temperature and pressure. Key words: PQLX, PDFs, PSDs, Broad Band

Alili, Azouaou; Yelles-chaouche, Abd el karim; Allili, Toufik; Messemen, Walid

2014-05-01

259

Antimisting kerosene: Base fuel effects, blending and quality control techniques  

NASA Technical Reports Server (NTRS)

The problems associated with blending of the AMK additive with Jet A, and the base fuel effects on AMK properties are addressed. The results from the evaluation of some of the quality control techniques for AMK are presented. The principal conclusions of this investigation are: significant compositional differences for base fuel (Jet A) within the ASTM specification DI655; higher aromatic content of the base fuel was found to be beneficial for the polymer dissolution at ambient (20 C) temperature; using static mixer technology, the antimisting additive (FM-9) is in-line blended with Jet A, producing AMK which has adequate fire-protection properties 15 to 20 minutes after blending; degradability of freshly blended and equilibrated AMK indicated that maximum degradability is reached after adequate fire protection is obtained; the results of AMK degradability as measured by filter ratio, confirmed previous RAE data that power requirements to decade freshly blended AMK are significantly higher than equilibrated AMK; blending of the additive by using FM-9 concentrate in Jet A produces equilibrated AMK almost instantly; nephelometry offers a simple continuous monitoring capability and is used as a real time quality control device for AMK; and trajectory (jet thurst) and pressure drop tests are useful laboratory techniques for evaluating AMK quality.

Yavrouian, A. H.; Ernest, J.; Sarohia, V.

1984-01-01

260

Quality assurances: Decreasing clinically irrelevant testing from clinical microbiology laboratories, part II  

Microsoft Academic Search

Laboratorians are well aware of the old adage “garbage in, garbage out.” Contemporary clinical microbiologists now need to make proactive efforts to ensure “quality in, quality out” by improving the pre-analytical and post-analytical components of samples sent to the microbiology laboratory for testing. Part II of this article will focus on recommendations to produce clinically relevant information for urine, stool,

Joan Barenfanger

2006-01-01

261

National Research Laboratory Generic Project Quality Assurance Plan for Research and Development.  

National Technical Information Service (NTIS)

This Project Quality Assurance Plan (PQAP) sets forth the requirements for the National Research Laboratory's research Divisions' quality assurance programs to comply with the applicable criteria of 10CFR Part 50, Appendix B, ANSI/ASME NQA-1 and to meet t...

E. E. Bain R. L. Hinckley

1986-01-01

262

10 CFR 26.167 - Quality assurance and quality control.  

Code of Federal Regulations, 2010 CFR

...HHS-certified laboratory must use an immunoassay that meets the requirements of the Food...commercial distribution. Non-instrumented immunoassay testing devices that are pending HHS...an HHS-certified laboratory may use immunoassay technique âAâ for all drugs...

2009-01-01

263

10 CFR 26.167 - Quality assurance and quality control.  

Code of Federal Regulations, 2010 CFR

...HHS-certified laboratory must use an immunoassay that meets the requirements of the Food...commercial distribution. Non-instrumented immunoassay testing devices that are pending HHS...an HHS-certified laboratory may use immunoassay technique âAâ for all drugs...

2010-01-01

264

External quality assurance performance of clinical research laboratories in sub-saharan Africa.  

PubMed

Patient Safety Monitoring in International Laboratories (JHU-SMILE) is a resource at Johns Hopkins University that supports and monitors laboratories in National Institutes of Health-funded international clinical trials. To determine the impact of the JHU-SMILE quality assurance scheme in sub-Saharan African laboratories, we reviewed 40 to 60 months of external quality assurance (EQA) results of the College of American Pathologists (CAP) in these laboratories. We reviewed the performance of 8 analytes: albumin, alanine aminotransferase, creatinine, sodium, WBC, hemoglobin, hematocrit, and the human immunodeficiency virus antibody rapid test. Over the 40- to 60-month observation period, the sub-Saharan laboratories had a 1.63% failure rate, which was 40% lower than the 2011 CAP-wide rate of 2.8%. Seventy-six percent of the observed EQA failures occurred in 4 of the 21 laboratories. These results demonstrate that a system of remote monitoring, feedback, and audits can support quality in low-resource settings, even in places without strong regulatory support for laboratory quality. PMID:23086773

Amukele, Timothy K; Michael, Kurt; Hanes, Mary; Miller, Robert E; Jackson, J Brooks

2012-11-01

265

Audit of controls over Superconducting Super Collider Laboratory subcontractor expenditures  

SciTech Connect

In January 1989 the Department of Energy contracted with Universities Research Association, Inc. to design, construct, manage, operate, and maintain the Superconducting Super Collider Laboratory. Through Fiscal Year 1992, costs for subcontractor goods and services accounted for about 75 percent of the Superconducting Super Collider Laboratory expenditures. The Office of Inspector General evaluated the adequacy of controls in place to ensure that subcontractor costs were reasonable, as required by the contract. The following conclusions were drawn from the audit. The Superconducting Super Collider Laboratory did not consistently exercise prudent business judgment in making subcontractor expenditures. As a result, $60 million in expenditures already made and $128 million planned with commercial subcontractors were, in the authors opinion, unnecessary, excessive, or represented uncontrolled growth. The audit also found inadequate justifications, accountability, and cost controls over $143 million in expenditures made and $47 million planned with other Department of Energy laboratories. Improvements were needed in subcontract administration and internal controls, including appropriate audit coverage of the subcontracts. In addition, Department of Energy guidance concerning procurement actions between the laboratories needed to be established.

Not Available

1993-10-22

266

Microstructure analysis of dental castings used in fixed dental prostheses—a simple method for quality control  

Microsoft Academic Search

The aim of this study was to evaluate the microstructural quality of noble alloy castings from commercial dental laboratories\\u000a using the wiping–etching method as a simple method for quality control. In total, 240 castings from two noble alloys (AuAgCuPt\\u000a and AuPtZn) were taken from a day's production of five different dental laboratories. The casting quality was evaluated by\\u000a determining the

Christian Mehl; Björn Lang; Heinrich Kappert; Matthias Kern

2011-01-01

267

Passive ventilation for residential air quality control  

SciTech Connect

Infiltration has long served the residential ventilation needs in North America. In Northern Europe it has been augmented by purpose-provided natural ventilation systems--so-called passive ventilation systems--to better control moisture problems in dwellings smaller than their North American counterparts and in a generally wetter climate. The growing concern for energy consumption, and the environmental impacts associated with it, has however led to tighter residential construction standards on both continents and as a result problems associated with insufficient background ventilation have surfaced. Can European passive ventilation systems be adapted for use in North American dwellings to provide general background ventilation for air quality control? This paper attempts to answer this question. The configuration, specifications and performance of the preferred European passive ventilation system--the passive stack ventilation (PSV) system--will be reviewed; innovative components and system design strategies recently developed to improve the traditional PSV system performance will be outlined; and alternative system configurations will be presented that may better serve the climatic extremes and more urban contexts of North America. While these innovative and alternative passive ventilation systems hold great promise for the future, a rational method to size the components of these systems to achieve the control and precision needed to meet the conflicting constraints of new ventilation and air tightness standards has not been forthcoming. Such a method will be introduced in this paper and an application of this method will be presented.

Axley, J.

1999-07-01

268

External Quality Assessment Scheme for reference laboratories - review of 8 years' experience.  

PubMed

We describe an External Quality Assessment Scheme (EQAS) intended for reference (calibration) laboratories in laboratory medicine and supervised by the Scientific Division of the International Federation of Clinical Chemistry and Laboratory Medicine and the responsible Committee on Traceability in Laboratory Medicine. The official EQAS website, RELA (www.dgkl-rfb.de:81), is open to interested parties. Information on all requirements for participation and results of surveys are published annually. As an additional feature, the identity of every participant in relation to the respective results is disclosed. The results of various groups of measurands (metabolites and substrates, enzymes, electrolytes, glycated hemoglobins, proteins, hormones, thyroid hormones, therapeutic drugs) are discussed in detail. The RELA system supports reference measurement laboratories preparing for accreditation according to ISO 17025 and ISO 15195. Participation in a scheme such as RELA is one of the requirements for listing of the services of a calibration laboratory by the Joint Committee on Traceability in Laboratory Medicine. PMID:23327864

Kessler, Anja; Siekmann, Lothar; Weykamp, Cas; Geilenkeuser, Wolf Jochen; Dreazen, Orna; Middle, Jonathan; Schumann, Gerhard

2013-05-01

269

Quality control of VLT ISAAC data  

NASA Astrophysics Data System (ADS)

For 3 years the Infrared Spectrometer And Array Camera (ISAAC) has been operating at the 8m Antu (UT1) telescope of the European Southern Observatory Very Large Telescope (ESO VLT). As part of ESO data flow operations ISAAC data are processed and quality control checked by the Data Flow Operations group (often known as QC Garching). at ESO headquarters in Garching. The status of the instrument is checked in terms of QC parameters, which are derived from raw and processed data and compared against reference values. Low level parameters include detector temperature and zero level offset, other parameters include image quality and spectrum curvature. Complicated instrumental behaviors like the odd-even column effect and the appearance of pupil ghosts require more sophisticated QC tools. Instrumental interventions of cryogenic instruments like ISAAC include a defrost and re-freeze sequence which can be traced in trending plots of the QC1 parameters, which are published regularly (see http://www.eso.org/qc). We present recent highlights of the ISAAC QC process and their role as feedback to the observatory to retain the performance of the instrument.

Hummel, Wolfgang; Lidman, Christopher; Devillard, Nicolas; Jung, Yves; Johnson, Rachael; Doublier, Vanessa

2002-12-01

270

Quality control of VLT-UVES data  

NASA Astrophysics Data System (ADS)

UVES is the UV-Visual high-resolution echelle spectrograph mounted at the 8.2m Kueyen (UT2) telescope of the ESO Very Large Telescope. Its data products are pipeline-processed and quality checked by the Data Flow Operations Group (often known as QC Garching). Calibration data are processed to create calibration products and to extract Quality Control (QC) parameters. These parameters provide instrument health checks and monitor instrument performance. Typical UVES QC parameters are: bias level, read-out-noise, dark current of the three CCD detectors used in the instrument, rms of dispersion, resolving power, CCD pixel-to-pixel gain structure, instrument efficiency. The measured data are fed into a database, compared to earlier data, trended over time and published on the web (http://www.eso.org/qc/index_uves.html). The QC system has evolved with time and proven to be extremely useful. Some examples are given which highlight the impact of careful QC on instrument performance.

Hanuschik, Reinhard W.; Kaufer, Andreas; Modigliani, Andrea; D'Odorico, Sandro; Dekker, Hans

2002-12-01

271

10 CFR 26.167 - Quality assurance and quality control.  

... (1) Confirmatory tests for drugs and drug metabolites must be performed using gas chromatography/mass spectrometry (GC/MS) or other confirmatory test methodologies that HHS-certified laboratories are permitted to use in Federal workplace drug...

2014-01-01

272

[Evaluating an internal quality control procedure: application to multidimensional control].  

PubMed

Internal quality control keeps in constant evolution in the industrial world. Introducing in clinical chemistry new QC methods derived from the industrial practice raises the point of the means for their evaluation. The main evaluation criteria are discussed in this paper. The importance of ARL (average run length) as a key-criterion of the efficiency of a quality control procedure is stressed. These principles were applied to the multivariate approach of multilevel control with the Hotelling's T2. This method led to a better detection of random errors than the independently managed conventional Shewhart (Levey- Jennings) charts. Applied to systematic errors, both methods gave similar results with a certain lack of sensitivity. However the multivariate method can be sensitised using EWMA (exponentially weighted moving average), a method specific for improved bias detection. EWMA efficiency outperforms that of the older systems of rules. Moreover, in any kind of error, multivariate approach secures a well-defined false rejection rate, whereas this rate is dependant on unknown inter-level correlation coefficients in conventional QC. PMID:12368148

Marquis, P; Masseyeff, R

2002-01-01

273

mRNA quality control goes transcriptional  

PubMed Central

Eukaryotic mRNAs are extensively processed to generate functional transcripts, which are 5? capped, spliced and 3? polyadenylated. Accumulation of unprocessed (aberrant) mRNAs can be deleterious for the cell, hence processing fidelity is closely monitored by QC (quality control) mechanisms that identify erroneous transcripts and initiate their selective removal. Nucleases including Xrn2/Rat1 and the nuclear exosome have been shown to play an important role in the turnover of aberrant mRNAs. Recently, with the growing appreciation that mRNA processing occurs concomitantly with polII (RNA polymerase II) transcription, it has become evident that QC acts at the transcriptional level in addition to degrading aberrant RNAs. In the present review, we discuss mechanisms that allow cells to co-transcriptionally initiate the removal of RNAs as well as down-regulate transcription of transcripts where processing repeatedly fails.

Kilchert, Cornelia; Vasiljeva, Lidia

2013-01-01

274

Quality control of radiation therapy equipment.  

PubMed

A review is given dealing mainly with the quality control functional performance characteristics of medical electron accelerators as the leading case of all equipment for radiotherapy. The International Electrotechnical Commission (IEC) has prepared a standard and a report, which are now in print. The standard addresses the definition of functional performance characteristics, the specification of test methods and conditions and the obligation of the manufacturer to declare the actual performance values of his equipment in a standardized format. In Germany, a translation of this standard is published as draft standard DIN 6847 part 4. IEC has prepared for simplified test procedures a report with guidelines and a reduced volume of test conditions for periodic tests during the working life of the accelerator. In Germany a standard DIN 6847 part 5 is published on "constancy checks" which is slightly but characteristically different from the IEC Report. The differences are schematically listed and discussed. PMID:3406452

Rassow, J

1988-05-01

275

Problems of quality control in constructing earth dams  

Microsoft Academic Search

Conclusion 1.Current methods of conducting geotechnical control when constructing high earth dams do not have effective criteria for evaluating the technology and therefore they cannot provide real quality control of dam construction.2.A system of controlling the quality of constructing earth dams with the use of the technology safety factor analogous to the soil safety factor, realizing feedback of geotechnical control

A. G. Chernilov

1987-01-01

276

Approaches to Quality of Control in Diabetes Care  

Microsoft Academic Search

Management methods for quality of diabetes care need new approaches because of the poor metabolic control of most of these patients. Poor quality of care generally results from poor instruction and training rather than from misbehaviour of both patients and their families. Structure quality of care (who and where?), process quality (how?, which are the goals, what resolution is taken

F. Chiarelli; A. Verrotti; L. di Ricco; M. de Martino; G. Morgese

1998-01-01

277

Setting up and running a control research laboratory  

Microsoft Academic Search

Setting up and managing a control research laboratory can be a time-consuming and labor-intensive undertaking. The author offers helpful advice based on his own experience, much of it learned by sometimes painful trial and error, in the hope that this advice will help you avoid some of the difficulties that you might otherwise encounter. Questions addressed are whether to build

D. S. Bernstein

2003-01-01

278

Experimenting from a Distance--Remotely Controlled Laboratory (RCL)  

ERIC Educational Resources Information Center

The use of computers and multimedia, as well as the World Wide Web and new communication technologies, allows new forms of teaching and learning such as distance learning, blended learning, use of virtual libraries and many more. The herewith discussed remotely controlled laboratory (RCL) project shall offer an additional contribution. The basic…

Grober, Sebastian; Vetter, Martin; Eckert, Bodo; Jodl, Hans-Jorg

2007-01-01

279

Millikan's Oil-Drop Experiment as a Remotely Controlled Laboratory  

ERIC Educational Resources Information Center

The Millikan oil-drop experiment, to determine the elementary electrical charge e and the quantization of charge Q = n [middle dot] e, is an essential experiment in physics teaching but it is hardly performed in class for several reasons. Therefore, we offer this experiment as a remotely controlled laboratory (RCL). We describe the interactivity…

Eckert, Bodo; Grober, Sebastian; Vetter, Martin; Jodl, Hans-Jorg

2012-01-01

280

Multifamily Quality Control Inspector Job/Task Analysis and Report.  

National Technical Information Service (NTIS)

The U.S. Department of Energy (DOE) Weatherization Assistance Program (WAP) and the National Renewable Energy Laboratory (NREL) have developed the Guidelines for Home Energy Professionals (Guidelines) project to support and promote high-quality energy upg...

C. Larney C. M. Owens

2013-01-01

281

Generic quality assurance/quality control guide for photovoltaic concentrator design, development and system installation  

NASA Astrophysics Data System (ADS)

The U.S. Department of Energy National Photovoltaics Program considers the photovoltaic (PV) concentrator technology as a viable entity, likely to penetrate the utility market in the foreseeable future. To achieve this, it has launched the National Photovoltaic Concentrator Initiative under the management of Sandia National Laboratories. The objective of this program is to encourage PV concentrator system design and manufacture, with a view to bringing the energy cost to $0.12/kWh in the next four years and to $0.06/kWh by the year 2000. To achieve these goals, the systems have to perform reliably for 20 to 30 years. This necessitates a stringent quality assurance/quality control (QA/QC) program in all phases of PV concentrator design, production, and installation. In order to assist the PV industry in this effort a project was initiated to provide a generic QA/QC guide, capable of being adapted by any PV concentrator industry to prepare its individual QA/QC plan. The draft plan of the guide was prepared and circulated to various government laboratories and industries involved in PV concentrator work. Their input is now being incorporated into a final document, which will serve as an industry standard.

Murty, V. S.; Chamberlin, J. L.

282

Utilization of a computer-controlled laboratory workstation (Biomek 1000) in routine radioimmunoassay laboratory.  

PubMed

The suitability and performance characteristics of a recently introduced computer-controlled laboratory workstation (Biomek 1000) for use in automating sample transfer and reagent additions in radioimmunoassay techniques were assessed. The system is based on the use of disposable tips and, therefore, reduces any possible sample carry-over and eliminates the need for priming with the subsequent reduction in cost of reagents. However, the machine lacks the useful option of liquid-level sensing facility. Acceptable technical performance in terms of precision, accuracy and throughput was obtained with the Biomek 1000 which complied with international recommendations on the safety of hospital laboratory equipment. PMID:2208988

Hassan, M A; Issac, D

1990-01-01

283

Quality control and the practice of clinical psychology  

Microsoft Academic Search

Because of current health care reforms, quality control, accountability, and cost-effectiveness have become important issues in the practice of clinical psychology. It is imperative that practicing clinicians begin to evaluate their services to assess whether they demonstrate high quality and cost-effectiveness, as well as a continued commitment to qualify improvement. Deming's (1986) approach to quality control is discussed as a

Elizabeth A. Yeater; P GRACZYK

1998-01-01

284

Technical support document for water quality-based toxics control  

Microsoft Academic Search

The reports provides guidance for each step in the water quality-based toxics control process from screening to compliance monitoring; Section 1 discusses the advantages and disadvantages of two approaches to toxics control: toxicity testing and chemical specific assessment; Section 2, Water Quality Criteria and Standards, contains a brief discussion of water-quality standards and the derivation of ambient criteria to attain

R. Brandes; B. Newton; M. Owens; E. Southerland

1985-01-01

285

Quality-assurance results for routine water analysis in US Geological Survey laboratories, water year 1991  

USGS Publications Warehouse

The US. Geological Survey operates a quality- assurance program based on the analyses of reference samples for the National Water Quality Laboratory in Arvada, Colorado, and the Quality of Water Service Unit in Ocala, Florida. Reference samples containing selected inorganic, nutrient, and low ionic-strength constituents are prepared and disguised as routine samples. The program goal is to determine precision and bias for as many analytical methods offered by the participating laboratories as possible. The samples typically are submitted at a rate of approximately 5 percent of the annual environmental sample load for each constituent. The samples are distributed to the laboratories throughout the year. Analytical data for these reference samples reflect the quality of environmental sample data produced by the laboratories because the samples are processed in the same manner for all steps from sample login through data release. The results are stored permanently in the National Water Data Storage and Retrieval System. During water year 1991, 86 analytical procedures were evaluated at the National Water Quality Laboratory and 37 analytical procedures were evaluated at the Quality of Water Service Unit. An overall evaluation of the inorganic (major ion and trace metal) constituent data for water year 1991 indicated analytical imprecision in the National Water Quality Laboratory for 5 of 67 analytical procedures: aluminum (whole-water recoverable, atomic emission spectrometric, direct-current plasma); calcium (atomic emission spectrometric, direct); fluoride (ion-exchange chromatographic); iron (whole-water recoverable, atomic absorption spectrometric, direct); and sulfate (ion-exchange chromatographic). The results for 11 of 67 analytical procedures had positive or negative bias during water year 1991. Analytical imprecision was indicated in the determination of two of the five National Water Quality Laboratory nutrient constituents: orthophosphate as phosphorus and phosphorus. A negative or positive bias condition was indicated in three of five nutrient constituents. There was acceptable precision and no indication of bias for the 14 low ionic-strength analytical procedures tested in the National Water Quality Laboratory program and for the 32 inorganic and 5 nutrient analytical procedures tested in the Quality of Water Service Unit during water year 1991.

Maloney, T. J.; Ludtke, A. S.; Krizman, T. L.

1994-01-01

286

21 CFR 106.1 - Status and applicability of the quality control procedures regulation.  

Code of Federal Regulations, 2010 CFR

...and applicability of the quality control procedures regulation. 106.1...CONSUMPTION INFANT FORMULA QUALITY CONTROL PROCEDURES General Provisions ...and applicability of the quality control procedures regulation....

2009-04-01

287

21 CFR 106.1 - Status and applicability of the quality control procedures regulation.  

Code of Federal Regulations, 2010 CFR

...and applicability of the quality control procedures regulation. 106.1...CONSUMPTION INFANT FORMULA QUALITY CONTROL PROCEDURES General Provisions ...and applicability of the quality control procedures regulation....

2010-04-01

288

Indoor air quality: sources and control  

SciTech Connect

The nature of the indoor air quality problem is described; methods of control or reduction of indoor radon and radon progeny concentrations have been reviewed. These techniques may be categorized as radon source reduction, radon removal, and radon progeny removal. There are a number of potential sources of radon in US housing, including soil, potable water, and building materials. In most cases, it appears that flow of radon-bearing soil gas into houses, driven by a slight negative pressure differential across the building shell, is a major source of indoor radon; this pressure-driven flow appears to be the most likely source of radon that can account for the elevated radon concentrations observed in some houses. There are a number of radon source control techniques; their effectiveness will depend upon characteristics of the house substructure and the details of the specific application. While the results of such remedial measures have varied and the data base from which to generalize is small, five-to-ten-fold reductions in radon concentration have been reported. 31 references, 4 figures.

Sextro, R.G.; Nero, A.V.; Grimsrud, D.T.

1985-01-01

289

The spacecraft control laboratory experiment optical attitude measurement system  

NASA Technical Reports Server (NTRS)

A stereo camera tracking system was developed to provide a near real-time measure of the position and attitude of the Spacecraft COntrol Laboratory Experiment (SCOLE). The SCOLE is a mockup of the shuttle-like vehicle with an attached flexible mast and (simulated) antenna, and was designed to provide a laboratory environment for the verification and testing of control laws for large flexible spacecraft. Actuators and sensors located on the shuttle and antenna sense the states of the spacecraft and allow the position and attitude to be controlled. The stereo camera tracking system which was developed consists of two position sensitive detector cameras which sense the locations of small infrared LEDs attached to the surface of the shuttle. Information on shuttle position and attitude is provided in six degrees-of-freedom. The design of this optical system, calibration, and tracking algorithm are described. The performance of the system is evaluated for yaw only.

Welch, Sharon S.; Montgomery, Raymond C.; Barsky, Michael F.

1991-01-01

290

[Analysis of the results of the SEIMC External Quality Control Program. Year 2012].  

PubMed

The External Quality Control Program of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) include controls for bacteriology, serology, mycology, parasitology, mycobacteria, virology and molecular microbiology. This article presents the most relevant conclusions and lessons from the 2012 controls. As a whole, the results obtained in 2012 confirm the excellent skill and good technical standards found in previous editions. However, erroneous results can be obtained in any laboratory and in clinically relevant determinations. Once again, the results of this program highlighted the need to implement both internal and external controls in order to assure the maximal quality of the microbiological tests. PMID:24630577

de Gopegui Bordes, Enrique Ruiz; Guna Serrano, M del Remedio; Orta Mira, Nieves; Ovies, María Rosario; Poveda, Marta; Gimeno Cardona, Concepción

2014-02-01

291

[Recommendations for implementing the UNE-EN-ISO 15189 quality standard in the clinical microbiology laboratory: bacteriology and serology].  

PubMed

The UNE-EN-ISO 15189:2007 standard specifies the management and technical requirements that clinical microbiology laboratories must meet to achieve optimal quality when performing microbiological analyses. With implementation of this standard, a laboratory can receive the accreditation and formal recognition of an authorized body, certifying that it is apt for performing an assay or group of assays. In Spain, laboratories that apply these standards can be accredited by the Entidad Nacional de Acreditación (ENAC, Spanish accreditation body). The purpose of this review is to familiarize clinical microbiology laboratory specialists with the UNE-EN-ISO 15189:2007 standard through a practical approach focussed on bacteriology and serology studies. We briefly define the scope and specify the requisites required for managing the quality of the procedures and processes involved in performing tests on human specimens, for document control, and for management of instruments and equipment, personnel, information systems, supply systems, and external services. Lastly, evaluation approaches are indicated to achieve continuing improvement of the processes carried out and the services the laboratory provides. PMID:19811856

Rojo, María Dolores; Aguiar, Juan Manuel; Cercenado, Emilia; de Ory, Fernando; de la Rosa, Manuel

2010-11-01

292

Bacteriological Methods in Water Quality Control Programs. Training Manual.  

ERIC Educational Resources Information Center

This training manual presents material on basic bacteriological laboratory procedures as required by Federal Register Water Quality Guidelines. Course topics include: characteristics, occurrences, and significance of bacterial indicators of pollution; bacteriological water quality standards and criteria; collection and handling of samples;…

Office of Water Program Operations (EPA), Cincinnati, OH. National Training and Operational Technology Center.

293

Enhancement and quality control of GOES images  

NASA Astrophysics Data System (ADS)

The new generation of Geostationary Operational Environmental Satellites (GOES) have an imager instrument with five multispectral bands of high spatial resolution,and very high dynamic range radiance measurements with 10-bit precision. A wide variety of environmental processes can be observed at unprecedented time scales using the new imager instrument. Quality assurance and feedback to the GOES project office is performed using rapid animation at high magnification, examining differences between successive frames, and applying radiometric and geometric correction algorithms. Missing or corrupted scanline data occur unpredictably due to noise in the ground based receiving system. Smooth high resolution noise-free animations can be recovered using automatic techniques even from scanline scratches affecting more than 25 percent of the dataset. Radiometric correction using the local solar zenith angle was applied to the visible channel to compensate for time- of-day illumination variations to produce gain-compensated movies that appear well-lit from dawn to dusk and extend the interval of useful image observations by more than two hours. A time series of brightness histograms displays some subtle quality control problems in the GOES channels related to rebinning of the radiance measurements. The human visual system is sensitive to only about half of the measured 10- bit dynamic range in intensity variations, at a given point in a monochrome image. In order to effectively use the additional bits of precision and handle the high data rate, new enhancement techniques and visualization tools were developed. We have implemented interactive image enhancement techniques to selectively emphasize different subranges of the 10-bits of intensity levels. Improving navigational accuracy using registration techniques and geometric correction of scanline interleaving errors is a more difficult problem that is currently being investigated.

Jentoft-Nilsen, Marit; Palaniappan, Kannappan; Hasler, A. Frederick; Chesters, Dennis

1996-10-01

294

[Recommendations on the metrology and the control of the quality of the critical equipments].  

PubMed

Metrology resumes activities which allow the management of results measurement quality. In this paper, we present basic principles of metrology applied to the activities of laboratory medicine. We successively treat general concepts useful for laboratory staff, the interest in the definition of a metrological function and its activities field, the applications in measuring instruments necessary for the exams of medical biology, and the specific documentation control needed. PMID:23765023

Daunizeau, A

2013-06-01

295

TECHNICAL GUIDANCE DOCUMENT: QUALITY ASSURANCE AND QUALITY CONTROL FOR WASTE CONTAINMENT FACILITIES  

EPA Science Inventory

This Technical Guidance Document provides comprehensive guidance on procedures for quality assurance and quality control for waste containment facilities. The document includes a discussion of principles and concepts, compacted soil liners, soil drainage systems, geosynthetic dr...

296

TECHNICAL GUIDANCE DOCUMENT: QUALITY ASSURANCE AND QUALITY CONTROL FOR WASTE CONTAINMENT FACILITIES  

EPA Science Inventory

This Technical Guidance Document provides comprehensive guidance on procedures for quality assurance and quality control for waste containment facilities. he document includes a discussion of principles and concepts, compacted soil liners, soil drainage systems, geosynthetic drai...

297

QUALITY ASSURANCE AND QUALITY CONTROL FOR WASTE CONTAINMENT FACILITIES. Project Summary  

EPA Science Inventory

It is generally agreed that both quality assurance (QA) and quality control (QC) are essential to the proper installation and eventual performance of environmentally safe and secure waste containment systems. Even further, there are both manufacturing and construction aspects to...

298

Quality-assurance plan and field methods for quality-of-water activities, U.S. Geological Survey, Idaho National Engineering Laboratory, Idaho.  

National Technical Information Service (NTIS)

Water-quality activities at the Idaho National Engineering Laboratory (INEL) Project Office are part of the US Geological Survey's (USGS) Water Resources Division (WRD) mission of appraising the quantity and quality of the Nation's water resources. The pu...

L. J. Mann

1996-01-01

299

Sandia National Laboratories Advanced Simulation and Computing (ASC) Software Quality Plan. Plan 2: Mappings for the ASC Software Quality Engineering Practies. Version 2.0.  

National Technical Information Service (NTIS)

The purpose of the Sandia National Laboratories Advanced Simulation and Computing (ASC) Software Quality Plan is to clearly identify the practices that are the basis for continually improving the quality of ASC software products. The plan defines the ASC ...

C. A. Forsythe E. A. Bocheron H. C. Edwards M. Minana R. Heaphy R. R. Drake

2006-01-01

300

Sandia National Laboratories Advanced Simulation and Computing (ASC) Software Quality Plan Part 1: ASC Software Quality Engineering Practices Version 1.0. (January 2005).  

National Technical Information Service (NTIS)

The purpose of the Sandia National Laboratories Advanced Simulation and Computing (ASC) Software Quality Plan is to clearly identify the practices that are the basis for continually improving the quality of ASC software products. The plan defines the ASC ...

C. A. Forsythe E. A. Boucheron H. C. Edwards M. A. Ellis R. R. Drake

2005-01-01

301

Sandia National Laboratories Advanced Simulation and Computing (ASC) Software Quality Plan. Part 1: ASC Software Quality Engineering Practices, Version 2.0.  

National Technical Information Service (NTIS)

The purpose of the Sandia National Laboratories Advanced Simulation and Computing (ASC) Software Quality Plan is to clearly identify the practices that are the basis for continually improving the quality of ASC software products. The plan defines the ASC ...

A. L. Hodges C. A. Forsythe E. A. Boucheron H. C. Edwards R. Heaphy R. R. Drake

2006-01-01

302

Applications of quality assurance\\/quality control concepts to non-hardware project management  

Microsoft Academic Search

The concepts of Quality Assurance and Quality Control, developed over 40 years ago for high quantity production of hardware, are now routinely and effectively applied to complex, one-of-a-kind projects such as design and construction of nuclear power plants. Currently, Quality Assurance and Quality Control are being applied to projects where outputs are less tangible, e.g., software, services, technical judgements. To

Calek

1979-01-01

303

Slew maneuvers of Spacecraft Control Laboratory Experiment (SCOLE)  

NASA Technical Reports Server (NTRS)

This is the final report on the dynamics and control of slew maneuvers of the Spacecraft Control Laboratory Experiment (SCOLE) test facility. The report documents the basic dynamical equation derivations for an arbitrary large angle slew maneuver as well as the basic decentralized slew maneuver control algorithm. The set of dynamical equations incorporate rigid body slew maneuver and three dimensional vibrations of the complete assembly comprising the rigid shuttle, the flexible beam, and the reflector with an offset mass. The analysis also includes kinematic nonlinearities of the entire assembly during the maneuver and the dynamics of the interactions between the rigid shuttle and the flexible appendage. The equations are simplified and evaluated numerically to include the first ten flexible modes to yield a model for designing control systems to perform slew maneuvers. The control problem incorporates the nonlinear dynamical equations and is expressed in terms of a two point boundary value problem.

Kakad, Yogendra P.

1992-01-01

304

A Quality Control Model for Extended Enterprises and Its Implementation  

Microsoft Academic Search

Along with the intensification of global competition and the complexity of manufacturing products, cooperation among enterprises\\u000a becomes more intimately, and the range of quality control extends from internal to the external enterprises. Consequently,\\u000a previous quality control methods for internal enterprise have been difficult to meet the demands of extended enterprises.\\u000a To effectively realize the quality control of extended enterprises, it

Yongtao Qin; Liping Zhao; Yiyong Yao; Damin Xu

2007-01-01

305

Quality control of diffusion weighted images  

NASA Astrophysics Data System (ADS)

Diffusion Tensor Imaging (DTI) has become an important MRI procedure to investigate the integrity of white matter in brain in vivo. DTI is estimated from a series of acquired Diffusion Weighted Imaging (DWI) volumes. DWI data suffers from inherent low SNR, overall long scanning time of multiple directional encoding with correspondingly large risk to encounter several kinds of artifacts. These artifacts can be too severe for a correct and stable estimation of the diffusion tensor. Thus, a quality control (QC) procedure is absolutely necessary for DTI studies. Currently, routine DTI QC procedures are conducted manually by visually checking the DWI data set in a gradient by gradient and slice by slice way. The results often suffer from low consistence across different data sets, lack of agreement of different experts, and difficulty to judge motion artifacts by qualitative inspection. Additionally considerable manpower is needed for this step due to the large number of images to QC, which is common for group comparison and longitudinal studies, especially with increasing number of diffusion gradient directions. We present a framework for automatic DWI QC. We developed a tool called DTIPrep which pipelines the QC steps with a detailed protocoling and reporting facility. And it is fully open source. This framework/tool has been successfully applied to several DTI studies with several hundred DWIs in our lab as well as collaborating labs in Utah and Iowa. In our studies, the tool provides a crucial piece for robust DTI analysis in brain white matter study.

Liu, Zhexing; Wang, Yi; Gerig, Guido; Gouttard, Sylvain; Tao, Ran; Fletcher, Thomas; Styner, Martin

2010-03-01

306

The quality control theory of aging  

PubMed Central

The quality control (QC) theory of aging is based on the concept that aging is the result of a reduction in QC of cellular systems designed to maintain lifelong homeostasis. Four QC systems associated with aging are 1) inadequate protein processing in a distressed endoplasmic reticulum (ER); 2) histone deacetylase (HDAC) processing of genomic histones and gene silencing; 3) suppressed AMPK nutrient sensing with inefficient energy utilization and excessive fat accumulation; and 4) beta-adrenergic receptor (BAR) signaling and environmental and emotional stress. Reprogramming these systems to maintain efficiency and prevent aging would be a rational strategy for increased lifespan and improved health. The QC theory can be tested with a pharmacological approach using three well-known and safe, FDA-approved drugs: 1) phenyl butyric acid, a chemical chaperone that enhances ER function and is also an HDAC inhibitor, 2) metformin, which activates AMPK and is used to treat type 2 diabetes, and 3) propranolol, a beta blocker which inhibits BAR signaling and is used to treat hypertension and anxiety. A critical aspect of the QC theory, then, is that aging is associated with multiple cellular systems that can be targeted with drug combinations more effectively than with single drugs. But more importantly, these drug combinations will effectively prevent, delay, or reverse chronic diseases of aging that impose such a tremendous health burden on our society.

Ladiges, Warren

2014-01-01

307

Quality Control of Diffusion Weighted Images  

PubMed Central

Diffusion Tensor Imaging (DTI) has become an important MRI procedure to investigate the integrity of white matter in brain in vivo. DTI is estimated from a series of acquired Diffusion Weighted Imaging (DWI) volumes. DWI data suffers from inherent low SNR, overall long scanning time of multiple directional encoding with correspondingly large risk to encounter several kinds of artifacts. These artifacts can be too severe for a correct and stable estimation of the diffusion tensor. Thus, a quality control (QC) procedure is absolutely necessary for DTI studies. Currently, routine DTI QC procedures are conducted manually by visually checking the DWI data set in a gradient by gradient and slice by slice way. The results often suffer from low consistence across different data sets, lack of agreement of different experts, and difficulty to judge motion artifacts by qualitative inspection. Additionally considerable manpower is needed for this step due to the large number of images to QC, which is common for group comparison and longitudinal studies, especially with increasing number of diffusion gradient directions. We present a framework for automatic DWI QC. We developed a tool called DTIPrep which pipelines the QC steps with a detailed protocoling and reporting facility. And it is fully open source. This framework/tool has been successfully applied to several DTI studies with several hundred DWIs in our lab as well as collaborating labs in Utah and Iowa. In our studies, the tool provides a crucial piece for robust DTI analysis in brain white matter study.

Liu, Zhexing; Wang, Yi; Gerig, Guido; Gouttard, Sylvain; Tao, Ran; Fletcher, Thomas; Styner, Martin

2013-01-01

308

Comparison of laboratory and field remote sensing methods to measure forage quality.  

PubMed

Recent research in range ecology has emphasized the importance of forage quality as a key indicator of rangeland condition. However, we lack tools to evaluate forage quality at scales appropriate for management. Using canopy reflectance data to measure forage quality has been conducted at both laboratory and field levels separately, but little work has been conducted to evaluate these methods simultaneously. The objective of this study is to find a reliable way of assessing grassland quality through measuring forage chemistry with reflectance. We studied a mixed grass ecosystem in Grasslands National Park of Canada and surrounding pastures, located in southern Saskatchewan. Spectral reflectance was collected at both in-situ field level and in the laboratory. Vegetation samples were collected at each site, sorted into the green grass portion, and then sent to a chemical company for measuring forage quality variables, including protein, lignin, ash, moisture at 135 °C, Neutral Detergent Fiber (NDF), Acid Detergent Fiber (ADF), Total Digestible, Digestible Energy, Net Energy for Lactation, Net Energy for Maintenance, and Net Energy for Gain. Reflectance data were processed with the first derivative transformation and continuum removal method. Correlation analysis was conducted on spectral and forage quality variables. A regression model was further built to investigate the possibility of using canopy spectral measurements to predict the grassland quality. Results indicated that field level prediction of protein of mixed grass species was possible (r² = 0.63). However, the relationship between canopy reflectance and the other forage quality variables was not strong. PMID:20948940

Guo, Xulin; Wilmshurst, John F; Li, Zhaoqin

2010-09-01

309

Description of a laboratory model Annular Momentum Control Device (AMCD)  

NASA Technical Reports Server (NTRS)

The basic concept of the Annular Momentum Control Device (AMCD) is that of a rotating annular rim suspended by noncontacting magnetic bearings and driven by a noncontacting electromagnetic spin motor. The purpose of this paper is to highlight some of the design requirements for AMCD's in general and describe how these requirements were met in the implementation of laboratory test model AMCD. An AMCD background summary is presented.

Groom, N. J.

1984-01-01

310

Annular Momentum Control Device (AMCD). Volume 1: Laboratory model development  

NASA Technical Reports Server (NTRS)

The annular momentum control device (AMCD) a thin hoop-like wheel with neither shaft nor spokes is described. The wheel floats in a magnetic field and can be rotated by a segmented motor. Potential advantages of such a wheel are low weight, configuration flexibility, a wheel that stiffens with increased speed, vibration isolation, and increased reliability. The analysis, design, fabrication, and testing is described of the laboratory model of the AMCD.

1975-01-01

311

On the use of a laser Doppler vibrometer for quality control of picture tubes  

Microsoft Academic Search

Currently, the scanning laser Doppler vibrometer (SLDV) has become a standard laboratory tool for high spatial resolution vibration measurements. Though the quality of the measurement result is very high in well-controlled experiments, there are still some limitations on the application in harsh industrial environments. Firstly, the user interaction of available SLDV systems is too high, requiring trained personnel. But more

Steve Vanlanduit; Peter Verboven; Bart Cauberghe; Louis Huysmans; Patrick Guillaume

2004-01-01

312

[Definition and control of the processes involved in the quality management].  

PubMed

The aim of this article is to describe the processes involved in the organisation and function of the medical laboratory to fulfill the needs of the users. The knowledge of the different interfaces and relationship is a condition for the control of the processes according to the quality management system. PMID:23765010

Daunizeau, A

2013-06-01

313

The quality control chart principle: application to the routine analysis of pesticide residues in water  

Microsoft Academic Search

In the routine analysis of pesticide residues in drinking water, a quality control chart (qcc) for every pesticide recorded the recovery from the fortification experiment which accompanied every series. The starting period included the first 10 recoveries and displayed the intra-laboratory performance in terms of the mean and of the ±3 standard deviations (sdv) confidence band. With every new recovery

Jiirgen Vogelgesang

1991-01-01

314

Construction Quality Control of Unbound Layers Based on Stiffness Modulus Criteria  

Microsoft Academic Search

NDT methods such as Portable Falling Weight Deflectometer (PFWD) provide measurements based on the engineering properties of materials (stiffness) instead of physical properties like field density and moisture content. However, PFWD testing method is not yet proven to be reliable enough for construction quality control. In this research, a laboratory testing unit box was prepared in which unbound materials were

Kamran Rafiei; Amir Kavussi; Shahaboddin Yasrobi

2012-01-01

315

Use of inert C&D materials for seawall foundation: Quality control measures  

Microsoft Academic Search

The technical viability of using inert construction and demolition (C&D) materials for the construction of seawall and breakwater foundations has been established by laboratory testing of the materials, numerical analysis of foundation stability, and a pilot field-scale engineering performance evaluation. However, quality control measures are still required so that only suitable materials are used for seawall and breakwater foundation construction.

Albert T. Yeung; L. G. Tham; Peter K. K. Lee; K. Y. Mok; Gordon Pei

2007-01-01

316

Geotechnical quality control: low-level radioactive waste and uranium mill tailings disposable facilities  

Microsoft Academic Search

Among the many responsibilities, the owner or licensee establishes and oversees the quality control (QC) of geotechnical aspects during construction, operation, and closure of low-level radioactive waste (LLW) or uranium mill tailings disposal facilities. This report first focuses on geotechnical QC practices by identifying the geotechnical parameters that should be considered along with appropriate laboratory and field testing and observation

H. V. Johnson; S. J. Spigolon; R. J. Lutton

1983-01-01

317

40 CFR 81.32 - Puget Sound Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2013 CFR

...2013-07-01 2013-07-01 false Puget Sound Intrastate Air Quality Control Region...Quality Control Regions § 81.32 Puget Sound Intrastate Air Quality Control Region. The Puget Sound Intrastate Air Quality Control...

2013-07-01

318

Vibration control for precision manufacturing at Sandia National Laboratories  

NASA Astrophysics Data System (ADS)

Sandia National Laboratories performs R&D in structural dynamics and vibration suppression for precision applications in weapon systems, space, underwater, transportation and civil structures. Over the last decade these efforts have expanded into the areas of active vibration control and 'smart' structures and material systems. In addition, Sandia has focused major resources towards technology to support weapon product development and agile manufacturing capability for defense and industrial applications. This paper will briefly describe the structural dynamics modeling and verification process currently in place at Sandia that supports vibration control and some specific applications of these techniques to manufacturing in the areas of lithography, machine tools and flexible robotics.

Hinnerichs, Terry; Martinez, David

319

Vibration control for precision manufacturing at Sandia National Laboratories  

NASA Astrophysics Data System (ADS)

Sandia National Laboratories performs R&D in structural dynamics and vibration suppression of precision applications in weapon systems, space, underwater, transportation and civil structures. Over the last decade these efforts have expanded into the areas of active vibration control and 'smart' structures and material systems, In addition, major resources have been focused towards technology to support weapon product development and agile manufacturing capability for defense and industrial applications. This paper will briefly describe the structural dynamics modeling and verification process that supports vibration control and some specific applications of these techniques to manufacturing in the areas of lithography, machine tools and flexible robotics.

Hinnerichs, Terry D.; Martinez, David R.

1995-05-01

320

Quality-assurance plan for the analysis of fluvial sediment by the U.S. Geological Survey Kentucky Water Science Center Sediment Laboratory  

USGS Publications Warehouse

This report describes laboratory procedures used by the U.S. Geological Survey Kentucky Water Science Center Sediment Laboratory for the processing and analysis of fluvial-sediment samples for concentration of sand and finer material. The report details the processing of a sediment sample through the laboratory from receiving the sediment sample, through the analytical process, to compiling results of the requested analysis. Procedures for preserving sample integrity, calibrating and maintaining of laboratory and field instruments and equipment, analyzing samples, internal quality assurance and quality control, and validity of the sediment-analysis results also are described. The report includes a list of references cited and a glossary of sediment and quality-assurance terms.

Shreve, Elizabeth A.; Downs, Aimee C.

2005-01-01

321

Networked Digital Control and Data Acquisition for an Undergraduate Controls and Robotics Laboratory: A Progress Report  

Microsoft Academic Search

This paper outlines the development status of a multidisciplinary controls and robotics engineering laboratory for undergaduate electrical and mechanical entineering majors based on an integrated computer network of automated data acquision, analysis and control tools. Personal computers, the heart of the student workstations, are interfaced to analog computers for simulaton, and to actual hardware for control and automation of typical

Philip D. Olivier; Lola Boyce

1993-01-01

322

Integrated Quality Control Measurement Project. Findings and Corrective Actions.  

ERIC Educational Resources Information Center

The Integrated Quality Control Measurement Project (IQCMP) of the U.S. Department of Education measured the quality of awards distributed during the 1988-89 award year under the three major Title IV programs: the Pell Grant program, the Campus-Based programs, and the Stafford Loan program, in order to evaluate and improve the quality of the…

Price Waterhouse and Co., New York, NY.

323

Food and Nutrition Services Quality Control Management Program.  

ERIC Educational Resources Information Center

A program was conducted to improve the quality of food service through the training of 44 food and nutrition service employees in a 200-bed hospital. A 12-week quality control program was implemented to address four key areas: food temperatures, food accuracy, food quality, and dietary personnel. Learning strategies, emphasizing critical thinking…

Wimsatt-Fraim, Teresa S.

324

A combined AHP–GP model for quality control systems  

Microsoft Academic Search

Using the results of previous studies of service quality attributes, five sets of quality measures are identified. These indicators or measures, through the analytic hierarchy process (AHP), are then accurately and consistently weighted. The priority weights are, in turn, incorporated in a goal-programming model to help select the “best” set of quality control instruments for customer data collection purposes. The

Masood A. Badri

2001-01-01

325

Evolutionary game analysis on quality control of construction project  

Microsoft Academic Search

In order to analyze the effect of different behaviors of quality control department and construction contractor on the construction project quality management model, an evolutionary game model of construction project quality management was established. In this model, the effect and position of social responsibility and fines were carefully discussed and the dynamic evolutionary procedure and stable equilibrium of construction project

Lian-fa Ruan; Fu-ming Chen

2011-01-01

326

Statistical process control for radiotherapy quality assurance  

Microsoft Academic Search

Every quality assurance process uncovers random and systematic errors. These errors typically consist of many small random errors and a very few number of large errors that dominate the result. Quality assurance practices in radiotherapy do not adequately differentiate between these two sources of error. The ability to separate these types of errors would allow the dominant source(s) of error

Todd Pawlicki; Matthew Whitaker

2005-01-01

327

Multicentre determination of quality control strains and quality control ranges for antifungal susceptibility testing of yeasts and filamentous fungi using the methods of the Antifungal Susceptibility Testing Subcommittee of the European Committee on Antimicrobial Susceptibility Testing (AFST-EUCAST)  

Microsoft Academic Search

A multicentre study involving seven laboratories was performed using techniques recommended by the Antifungal Susceptibility Testing Subcommittee of the European Committee on Antimicrobial Suscepti- bility Testing (AFST-EUCAST) to evaluate and propose quality control ranges and strains for susceptibility testing of fermentative yeasts and filamentous fungi. Participating laboratories tested the susceptibilities of a panel of 12 encoded isolates to amphotericin B,

M. Cuenca-Estrella; M. C. Arendrup; E. Chryssanthou; E. Dannaoui; C. Lass-Florl; P. Sandven; A. Velegraki; J. L. Rodriguez-Tudela

2007-01-01

328

Importance of the Primary Radioactivity Standard Laboratory and Implementation of its Quality Management  

SciTech Connect

The paper presents some specific aspects of the implementation of the quality management in the Radionuclide Metrology Laboratory, from IFIN-HH, the owner of the primary Romanian standard in radioactivity. The description of the accreditation, according to the EN ISO/IEC 17025:2005, is presented.

Sahagia, Maria; Razdolescu, Anamaria Cristina; Luca, Aurelian; Ivan, Constantin ['Horia Hulubei' National Institute of Physics and Nuclear Engineering (IFIN-HH), 407 Atomistilor Street, PO Box MG-6, Magurele, Ilfov County, RO-077125 (Romania)

2007-04-23

329

Importance of the Primary Radioactivity Standard Laboratory and Implementation of its Quality Management  

NASA Astrophysics Data System (ADS)

The paper presents some specific aspects of the implementation of the quality management in the Radionuclide Metrology Laboratory, from IFIN-HH, the owner of the primary Romanian standard in radioactivity. The description of the accreditation, according to the EN ISO/IEC 17025:2005, is presented.

Sahagia, Maria; Razdolescu, Anamaria Cristina; Luca, Aurelian; Ivan, Constantin

2007-04-01

330

The making of a successful seminar: Pacific Northwest Laboratory`s {open_quotes}Quest for Quality{close_quotes}  

SciTech Connect

Five contractors located on or near the Hanford Site in southeastern Washington State support technical communications staffs, all trying to meet the needs of one primary customer the U.S. Department of Energy. Historically, these staffs have maintained different processes and standards with regard to document production, and little interaction or information-sharing has occurred. To begin remedying that situation, the communications staff of Pacific Northwest Laboratory, a multiprogram national laboratory located in Richland, Wash., planned and hosted a one-day {open_quotes}Quest for Quality{close_quotes} seminar. The seminar was the first of its kind to comprise technical communications professionals from all the local DOE prime contractors, including technical editors and writers, publications assistants, text processors, and document production staff. The goals of the seminar were to identify ways to improve the quality of Hanford`s communication products and processes, to strengthen ties among technical communications staffs, and to open the lines of communication for future collaborative efforts. An eight-person committee selected topics, arranged facilities, recruited speakers, coordinated activities, hosted the seminar, and prepared proceedings.

Lumetta, C.C.; Downs, S.L.; Parnell, K.A.; Allen, R.E.

1994-10-01

331

Acute placebo-controlled sleep laboratory studies and clinical follow-up with pramipexole in restless legs syndrome  

Microsoft Academic Search

.   In a single-blind, placebo-controlled crossover trial, the acute efficacy of the dopamine agonist pramipexole was investigated\\u000a in 11 restless legs syndrome (RLS) patients by sleep laboratory methods, with a clinical follow-up for 4 weeks. In 3 nights\\u000a (pre-treatment, placebo and drug night), objective sleep quality was determined by polysomnography (PSG), subjective sleep\\u000a and awakening quality by rating scales, objective

M. Saletu; P. Anderer; G. Saletu-Zyhlarz; C. Hauer; B. Saletu

2002-01-01

332

Reactive control and reasoning assistance for scientific laboratory instruments  

NASA Technical Reports Server (NTRS)

Scientific laboratory instruments that are involved in chemical or physical sample identification frequently require substantial human preparation, attention, and interactive control during their operation. Successful real-time analysis of incoming data that supports such interactive control requires: (1) a clear recognition of variance of the data from expected results; and (2) rapid diagnosis of possible alternative hypotheses which might explain the variance. Such analysis then aids in decisions about modifying the experiment protocol, as well as being a goal itself. This paper reports on a collaborative project at the NASA Ames Research Center between artificial intelligence researchers and planetary microbial ecologists. Our team is currently engaged in developing software that autonomously controls science laboratory instruments and that provides data analysis of the real-time data in support of dynamic refinement of the experiment control. the first two instruments to which this technology has been applied are a differential thermal analyzer (DTA) and a gas chromatograph (GC). coupled together, they form a new geochemicstry and microbial analysis tool that is capable of rapid identification of the organiz and mineralogical constituents in soils. The thermal decomposition of the minerals and organics, and the attendance release of evolved gases, provides data about the structural and molecular chemistry of the soil samples.

Thompson, David E.; Levinson, Richard; Robinson, Peter

1993-01-01

333

[On-site quality control of acupuncture randomized controlled trial: design of content and checklist of quality control based on PICOST].  

PubMed

To effectively guarantee quality of randomized controlld trial (RCT) of acupuncture and develop reasonable content and checklist of on-site quality control, influencing factors on quality of acupuncture RCT are analyzed and scientificity of quality control content and feasibility of on-site manipulation are put into overall consideration. Based on content and checklist of on-site quality control in National 11th Five-Year Plan Project Optimization of Comprehensive Treatment Plan for TCM in Prevention and Treatment of Serious Disease and Clinical Assessment on Generic Technology and Quality Control Research, it is proposed that on-site quality control of acupuncture RCT should be conducted with PICOST (patient, intervention, comparison, out come, site and time) as core, especially on quality control of interveners' skills and outcome assessment of blinding, and checklist of on-site quality control is developed to provide references for undertaking groups of the project. PMID:24796063

Li, Hong-Jiao; He, Li-Yun; Liu, Zhi-Shun; Sun, Ya-Nan; Yan, Shi-Yan; Liu, Jia; Zhao, Ye; Liu, Bao-Yan

2014-02-01

334

QUALITY CONTROL AND QUALITY ASSURANCE PROCEDURES FOR LEVEL 1 HEALTH EFFECTS BIOASSAYS  

EPA Science Inventory

The report documents the development of a program of quality control (QC) and quality assurance (QA) for the EPA Level 1 environmental assessment health effects bioassays to ensure that all data collected are of known and documented quality sufficient to meet their intended use. ...

335

Space Shuttle flying qualities and flight control system assessment study  

NASA Technical Reports Server (NTRS)

The suitability of existing and proposed flying quality and flight control system criteria for application to the space shuttle orbiter during atmospheric flight phases was assessed. An orbiter experiment for flying qualities and flight control system design criteria is discussed. Orbiter longitudinal and lateral-directional flying characteristics, flight control system lag and time delay considerations, and flight control manipulator characteristics are included. Data obtained from conventional aircraft may be inappropriate for application to the shuttle orbiter.

Myers, T. T.; Johnston, D. E.; Mcruer, D.

1982-01-01

336

The impact of quality control materials on the performance of an internal quality control system: 1. General considerations.  

PubMed

Quality assurance in clinical chemistry is based on statistical control procedures designed to maintain a certain level of quality. Decisions about acceptance or rejection of analytical series are made primarily from measurements of quality control materials. Such materials are most often of non-human origin; this may lead to false decisions due to non-identity of patient samples and quality control material. We have investigated the significance of non-identity between patient and control materials by running two separate quality control systems in parallel. A regular system used for acceptance or rejection of series, and a parallel system used for registration of the actual quality of the analytical routine work. The results from the latter system have not been available for the operator handling the control system used in routine work. Our study has confirmed the validity of an internal quality control system to achieve a certain level of analytical stability as expressed by the short-term and long-term precision. However, because ideal control materials are not always available, additional procedures to control accuracy, specificity, and detectability may be necessary. The usefulness of such procedures to properly handle error signals from quality control systems has been demonstrated. PMID:6599531

Hyltoft Petersen, P; Hørder, M; Blaabjerg, O; Jørgensen, P J

1984-01-01

337

Data Quality Objectives Supporting Radiological Air Emissions Monitoring for the Marine Sciences Laboratory, Sequim Site  

SciTech Connect

This document of Data Quality Objectives (DQOs) was prepared based on the U.S. Environmental Protection Agency (EPA) Guidance on Systematic Planning Using the Data Quality Objectives Process, EPA, QA/G4, 2/2006 (EPA 2006), as well as several other published DQOs. The intent of this report is to determine the necessary steps required to ensure that radioactive emissions to the air from the Marine Sciences Laboratory (MSL) headquartered at the Pacific Northwest National Laboratory’s Sequim Marine Research Operations (Sequim Site) on Washington State’s Olympic Peninsula are managed in accordance with regulatory requirements and best practices. The Sequim Site was transitioned in October 2012 from private operation under Battelle Memorial Institute to an exclusive use contract with the U.S. Department of Energy, Office of Science, Pacific Northwest Site Office.

Barnett, J. M.; Meier, Kirsten M.; Snyder, Sandra F.; Antonio, Ernest J.; Fritz, Brad G.; Poston, Theodore M.

2012-12-27

338

Artificial Intelligence Approach to Support Statistical Quality Control Teaching  

ERIC Educational Resources Information Center

Statistical quality control--SQC (consisting of Statistical Process Control, Process Capability Studies, Acceptance Sampling and Design of Experiments) is a very important tool to obtain, maintain and improve the Quality level of goods and services produced by an organization. Despite its importance, and the fact that it is taught in technical and…

Reis, Marcelo Menezes; Paladini, Edson Pacheco; Khator, Suresh; Sommer, Willy Arno

2006-01-01

339

A REAL OPTIONS DESIGN FOR QUALITY CONTROL CHARTS  

Microsoft Academic Search

We develop a financial model for a manufacturing process where quality can be affected by an assignable cause. We value the real options associated with applying a statistical process control chart using the Black-Scholes equation, binomial and pentanomial lattices, and Monte Carlo simulation methods. This valuation gives decision makers a way to choose the appropriate quality control strategy based on

HARRIET BLACK NEMBHARD; LEYUAN SHI; MEHMET AKTAN

2002-01-01

340

Liver phantom for quality control and training in nuclear medicine  

Microsoft Academic Search

In nuclear medicine, liver scintigraphy aims to verify organ function based on the radionuclide concentration in the liver and bile flow and is also used to detect tumors. Therefore it is necessary to perform quality control tests in the gamma camera before running the exam to prevent false results. Quality control tests of the gamma camera should thus be performed

Fernanda Carla Lima Ferreira; Divanizia Do Nascimento Souza

2011-01-01

341

Statistical Quality Control Process for Traditional Chinese Medicine  

Microsoft Academic Search

The statistical quality control process on raw materials and\\/or the final product of traditional Chinese medicine (TCM) is examined. We develop a statistical quality control (QC) method to assess a proposed consistency index of raw materials from different sources and\\/or final products manufactured at different sites. The idea is to construct a 95% confidence interval for a proposed consistency index

Siu-Keung Tse; Jang-yang Chang; Wei-Lun Su; Shein-Chung Chow; Chao Hsiung; Qingshu Lu

2006-01-01

342

Enhancing quality control in transportation construction through nondestructive testing  

Microsoft Academic Search

This paper addresses the growing need for modern nondestructive evaluation (NDE) techniques for quality control during the construction\\/fabrication stages of transportation infrastructure. While the use of NDE techniques for in-service monitoring of infrastructure is increasing, very little effort is currently being made to use NDE for construction quality control. This paper proposes the use of modern NDE techniques for inspection

Udaya B. Halabe; David R. Martinelli; Samer H. Petro

1999-01-01

343

PLANNING GUIDE FOR EVALUATING AGRICULTURAL NONPOINT SOURCE WATER QUALITY CONTROLS  

EPA Science Inventory

This manual is a guide for water quality planners in the evaluation and selection of agricultural nonpoint source controls for areas ranging in size from individual farms and subwatersheds to large regions. Such controls are specified in water quality plans developed in response ...

344

Accruals Quality and Internal Control over Financial Reporting  

Microsoft Academic Search

We examine the relation between accruals quality and internal controls using 705 firms that disclosed at least one material weakness from August 2002 to November 2005 and find that weaknesses are generally associated with poorly esti- mated accruals that are not realized as cash flows. Further, we find that this relation between weak internal controls and lower accruals quality is

Jeffrey T. Doyle; Weili Ge; Sarah McVay

2007-01-01

345

For and against a European quality control of training.  

PubMed

In a world of medicine that evolves more and more rapidly, sufficient quality of education in the arts and crafts of our discipline and control of this quality are essential for the progress and vitality of Ob/Gyn. There are variations in training within European countries but with the aim of harmonization in training programmes and the flexibility of quality control mechanisms we will meet our objective that is the high standards in the care of woman throughout Europe. PMID:11205701

Dimitrakakis, C; Michalas, S

2001-01-01

346

7 CFR 58.523 - Laboratory and quality control tests.  

Code of Federal Regulations, 2010 CFR

...Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT...UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE...Products, published by the American Public Health Association. (2)...

2010-01-01

347

Inter-laboratory study to improve the quality of the analysis of nutrients in rainwater chemistry  

NASA Astrophysics Data System (ADS)

This paper describes the results of an inter-laboratory study conducted for the analysis of nutrients (nitrate, ammonium, phosphate, total nitrogen (TN), and total phosphorus (TP)) in natural rainwater. For this purpose, rainwater samples were collected and aggregated in Singapore and homogenized. These samples were immediately filtered through 0.45 ?m membrane filters and autoclaved for 15 min at 80 °C in order to stabilize the nutrients. The homogeneity and the stability of nutrients were rigorously tested for a period of three months initially. Upon ensuring the homogeneity and stability, the samples were distributed to 15 different laboratories from various countries around the world (Australia, Brazil, India, Mauritius, Singapore, Slovenia, Spain, Taiwan, and USA). Almost all laboratories have reported the analytical results for nitrate whereas only 8 of the 15 laboratories reported results for other nutrients such as ammonium, phosphate, TN, and TP. The discrepancy was mainly due to the presence of these nutrients in low concentration levels (particularly ammonium ion and phosphate). Not all the laboratories were equipped with analytical capabilities to conduct the analysis of nutrients in low concentration levels. Further, the uncertainty associated with the analysis of TN and TP restricted the number of laboratories that could report their analytical data on nutrients. All 14 laboratories reported nitrate-nitrogen results which were in good agreement with each other (0.68 ± 0.07 mg l -1). Similarly, the results of TN and TP were also comparable among at least 8 laboratories. This inter-laboratory study on the analysis of nutrients in natural rainwater, conducted for the first time, provided an opportunity to the participating laboratories to assess and improve their laboratory performance, thereby, improving the quality of their analytical data.

Karthikeyan, Sathrugnan; Balasubramanian, Rajasekhar; He, Jun

348

Model Predictive Control of Unified Power Quality Conditioner for Power Quality Improvement  

Microsoft Academic Search

This paper presents a model predictive control (MPC) design for the unified power quality conditioner (UPQC), an integration of series and shunt active filters to improve power quality in a power distribution system. The control strategy aims to regulate the load voltage and the source current to the desired references in spite of the existence of harmonic components in the

K. H. Kwan; Y. S. Png; Y. C. Qui; P. L. So

2007-01-01

349

Ride quality sensitivity to SAS control law and to handling quality variations  

NASA Technical Reports Server (NTRS)

The RQ trends which large flexible aircraft exhibit under various parameterizations of control laws and handling qualities are discussed. A summary of the assumptions and solution technique, a control law parameterization review, a discussion of ride sensitivity to handling qualities, and the RQ effects generated by implementing relaxed static stability configurations are included.

Roberts, P. A.; Schmidt, D. K.; Swaim, R. L.

1976-01-01

350

Nuclear Technology Series. Course 14: Introduction to Quality Assurance/Quality Control.  

ERIC Educational Resources Information Center

This technical specialty course is one of thirty-five courses designed for use by two-year postsecondary institutions in five nuclear technician curriculum areas: (1) radiation protection technician, (2) nuclear instrumentation and control technician, (3) nuclear materials processing technician, (4) nuclear quality-assurance/quality-control

Technical Education Research Center, Waco, TX.

351

Teaching Quality Control with Chocolate Chip Cookies  

ERIC Educational Resources Information Center

Chocolate chip cookies are used to illustrate the importance and effectiveness of control charts in Statistical Process Control. By counting the number of chocolate chips, creating the spreadsheet, calculating the control limits and graphing the control charts, the student becomes actively engaged in the learning process. In addition, examining…

Baker, Ardith

2014-01-01

352

Low-Speed Active Flow Control Laboratory Developed  

NASA Technical Reports Server (NTRS)

The future of aviation propulsion systems is increasingly focused on the application of control technologies to significantly enhance the performance of a new generation of air vehicles. Active flow control refers to a set of technologies that manipulate the flow of air and combustion gases deep within the confines of an engine to dynamically alter its performance during flight. By employing active flow control, designers can create engines that are significantly lighter, are more fuel efficient, and produce lower emissions. In addition, the operating range of an engine can be extended, yielding safer transportation systems. The realization of these future propulsion systems requires the collaborative development of many base technologies to achieve intelligent, embedded control at the engine locations where it will be most effective. NASA Glenn Research Center s Controls and Dynamics Technology Branch has developed a state-of-the-art low-speed Active Flow Control Laboratory in which emerging technologies can be integrated and explored in a flexible, low-cost environment. The facility allows the most promising developments to be prescreened and optimized before being tested on higher fidelity platforms, thereby reducing the cost of experimentation and improving research effectiveness.

Culley, Dennis E.; Bright, Michelle M.

2005-01-01

353

The quality control chart for monitoring multivariate autocorrelated processes  

Microsoft Academic Search

Previously, quality control and improvement researchers discussed multivariate control charts for independent processes and univariate control charts for autocorrelated processes separately. We combine the two topics and propose vector autoregressive (VAR) control charts for multivariate autocorrelated processes. In addition, we estimate AR(p) models instead of ARMA models for the systematic cause of variation. We discuss the procedures to construct the

Jeffrey E. Jarrett; Xia Pan

2007-01-01

354

A Neural Network Approach to Quality Control Charts  

Microsoft Academic Search

In this paper Quality Control Charts without memory are compared to neural networks trained with the Backpropagation algorithm. Neural networks are used to decide whether a process is under statistical control or out of control. As only the last sample is used to decide upon the state of the production process, a comparison to Shewhart-control charts leads automatically to a

Thomas Stützle

1995-01-01

355

40 CFR 81.52 - Wasatch Front Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2010 CFR

...2010-07-01 2010-07-01 false Wasatch Front Intrastate Air Quality Control Region...Air Quality Control Regions § 81.52 Wasatch Front Intrastate Air Quality Control Region. The Wasatch Front Intrastate Air Quality...

2010-07-01

356

40 CFR 81.52 - Wasatch Front Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2010 CFR

...2009-07-01 2009-07-01 false Wasatch Front Intrastate Air Quality Control Region...Air Quality Control Regions § 81.52 Wasatch Front Intrastate Air Quality Control Region. The Wasatch Front Intrastate Air Quality...

2009-07-01

357

40 CFR 81.275 - Lake Tahoe Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2013 CFR

... 2013-07-01 2013-07-01 false Lake Tahoe Intrastate Air Quality Control Region...Air Quality Control Regions § 81.275 Lake Tahoe Intrastate Air Quality Control Region. The Lake Tahoe Intrastate Air Quality...

2013-07-01

358

40 CFR 81.273 - Lake County Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2013 CFR

... 2013-07-01 2013-07-01 false Lake County Intrastate Air Quality Control Region...Air Quality Control Regions § 81.273 Lake County Intrastate Air Quality Control Region. The Lake County Intrastate Air Quality...

2013-07-01

359

40 CFR 81.192 - Bluegrass Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2010 CFR

...2010-07-01 2010-07-01 false Bluegrass Intrastate Air Quality Control Region...Quality Control Regions § 81.192 Bluegrass Intrastate Air Quality Control Region. The Bluegrass Intrastate Air Quality...

2010-07-01

360

Agricultural biological reference materials for analytical quality control  

SciTech Connect

Cooperative work is under way at Agriculture Canada, US Department of Agriculture, and US National Bureau of Standards in an attempt to fill some of the gaps in the world repertoire of reference materials and to provide much needed control materials for laboratories' day to day operations. This undertaking involves the preparation and characterization of a number of agricultural and food materials for data quality control for inorganic constituents. Parameters considered in the development of these materials were material selection based on importance in commerce and analysis; techniques of preparation, processing, and packaging; physical and chemical characterization; homogeneity testing and quantitation (certification). A large number of agricultural/food products have been selected to represent a wide range of not only levels of sought-for constituents (elements) but also a wide range of matrix components such as protein, carbohydrate, dietary fiber, fat, and ash. Elements whose concentrations are being certified cover some two dozen major, minor, and trace elements of nutritional, toxicological, and environmental significance.

Ihnat, M.

1986-01-01

361

Improved Undergraduate Astronomy Laboratories with A Modern Telescope Control System  

NASA Astrophysics Data System (ADS)

We are in the middle of a cooperative astronomy education project to improve undergraduate laboratories at RPI (a PhD granting institution) and Siena College (a nearby liberal arts college). We have completed an overhaul of a 40-year-old, 16" B&C telescope on the RPI campus, and have made it available for hundreds of students at both schools, and once per week to the public. We have written an assessment test which was distributed to the students at the beginning and end of the Fall 2006 semester, which will be used as a baseline to determine whether the laboratory activities, which are currently under development, improve student learning in the Fall 2007 semester next year. The studio-style, hands-on, inquiry-based laboratories will be designed to challenge student misconceptions. In order to handle a large number of students using the main telescope and a limited number of smaller telescopes, we will cycle students through concurrent activities. This is enabled by the rapid acquisition and imaging of targets made possible by the upgrade to the control system of our 16" telescope. We demonstrate the productivity of our newly refurbished telescope, show the baseline results of our assessment, and present samples of activities under development. This project is funded by an NSF CCLI grant, 05-11340.

Milano, Anthony J.; Broder, D.; Finn, R.; Newberg, H.; Weatherwax, A.; Whittet, D.

2006-12-01

362

Using a distributed control system (DCS) for distillation column control in an undergraduate unit operations laboratory  

Microsoft Academic Search

This paper presents the main advantages of using an industrial distributed control system (DCS) in the operation of a distillation column which is used in an undergraduate unit operations laboratory course at the University of Texas at Austin. Taking advantage of the resources of an industrial DCS (friendly display options, an alarm management system, historical databases and advanced control tools),

Ivan Castillo; Thomas F. Edgar

2009-01-01

363

Quality indicators to detect pre-analytical errors in laboratory testing.  

PubMed

The identification of reliable quality indicators (QIs) is a crucial step in enabling users to quantify the quality of laboratory services. The current lack of attention to extra-laboratory factors is in stark contrast to the body of evidence pointing to the multitude of errors that continue to occur, particularly in the pre-analytical phase. The ISO 15189: 2012 standard for laboratory accreditation defines the pre-analytical phase, and recognizes the need to evaluate, monitor and improve all the procedures and processes in the initial phase of the testing cycle, including those performed in the phase of requesting tests and collecting samples, the so-called "pre-pre-analytical phase". Therefore, QIs should allow the identification of errors and non-conformities that can occur in all steps of the pre-analytical phase. Traditionally, pre-analytical errors are grouped into identification and sample problems. However, appropriate test requesting and complete request forms are now recognized as fundamental components in providing valuable laboratory services. The model of QIs developed by the Working Group of the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) includes indicators related to both identification and sample problems as well as all other pre-analytical defects, including those in test requesting and request forms. It, moreover, provides the framework (with objective criteria) necessary for promoting the harmonization of available QIs in the pre-analytical phase. PMID:24012653

Plebani, M; Sciacovelli, L; Aita, A; Padoan, A; Chiozza, M L

2014-05-15

364

Quality assurance guidance for laboratory assessment plates in support of EM environmental sampling and analysis activities  

SciTech Connect

This document is one of several guidance documents developed to support the EM (DOE Environmental Restoration and Waste Management) Analytical Services program. Its purpose is to introduce assessment plates that can be used to conduct performance assessments of an organization`s or project`s ability to meet quality goals for analytical laboratory activities. These assessment plates are provided as non-prescriptive guidance to EM-support organizations responsible for collection of environmental data for remediation and waste management programs at DOE facilities. The assessments evaluate objectively all components of the analytical laboratory process to determine their proper selection and use.

Not Available

1994-05-01

365

The EWMA control chart: properties and comparison with other quality-control procedures by computer simulation  

Microsoft Academic Search

A quality-control chart based on exponentially weighted moving averages (EWMA) has, in the past few years, become a popular tool for controlling inaccuracy in industrial quality control. In this paper, I explain the principles of this technique, present some numerical examples, and by computer simulation compare EWMA with other control charts currently used in clinical chemistry. The EWMA chart offers

Aljoscha Steffen Neubauer

366

Pacific Northwest National Laboratory Apatite Investigation at the 100-NR-2 Quality Assurance Project Plan  

SciTech Connect

This Quality Assurance Project Plan provides the quality assurance requirements and processes that will be followed by staff working on the 100-NR-2 Apatite Project. The U.S. Department of Energy, Fluor Hanford, Inc., Pacific Northwest National Laboratory, and the Washington Department of Ecology agreed that the long-term strategy for groundwater remediation at 100-N would include apatite sequestration as the primary treatment, followed by a secondary treatment. The scope of this project covers the technical support needed before, during, and after treatment of the targeted subsurface environment using a new high-concentration formulation.

Fix, N. J.

2008-03-28

367

Sandia National Laboratories, California Quality Assurance Project Plan for Environmental Monitoring Program.  

SciTech Connect

This Quality Assurance Project Plan (QAPP) applies to the Environmental Monitoring Program at the Sandia National Laboratories/California. This QAPP follows DOE Quality Assurance Management System Guide for Use with 10 CFR 830 Subpart A, Quality Assurance Requirements, and DOE O 414.1C, Quality Assurance (DOE G 414.1-2A June 17, 2005). The Environmental Monitoring Program is located within the Environmental Operations Department. The Environmental Operations Department is responsible for ensuring that SNL/CA operations have minimal impact on the environment. The Department provides guidance to line organizations to help them comply with applicable environmental regulations and DOE orders. To fulfill its mission, the department has groups responsible for waste management; pollution prevention, air quality; environmental planning; hazardous materials management; and environmental monitoring. The Environmental Monitoring Program is responsible for ensuring that SNL/CA complies with all Federal, State, and local regulations and with DOE orders regarding the quality of wastewater and stormwater discharges. The Program monitors these discharges both visually and through effluent sampling. The Program ensures that activities at the SNL/CA site do not negatively impact the quality of surface waters in the vicinity, or those of the San Francisco Bay. The Program verifies that wastewater and stormwater discharges are in compliance with established standards and requirements. The Program is also responsible for compliance with groundwater monitoring, and underground and above ground storage tanks regulatory compliance. The Program prepares numerous reports, plans, permit applications, and other documents that demonstrate compliance.

Holland, Robert C.

2005-09-01

368

The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers  

PubMed Central

Background The cerebrospinal fluid (CSF) biomarkers amyloid ? (A?)-42, total-tau (T-tau), and phosphorylated-tau (P-tau) demonstrate good diagnostic accuracy for Alzheimer’s disease (AD). However, there are large variations in biomarker measurements between studies, and between and within laboratories. The Alzheimer’s Association has initiated a global quality control program to estimate and monitor variability of measurements, quantify batch-to-batch assay variations, and identify sources of variability. In this article, we present the results from the first two rounds of the program. Methods The program is open for laboratories using commercially available kits for A?, T-tau, or P-tau. CSF samples (aliquots of pooled CSF) are sent for analysis several times a year from the Clinical Neurochemistry Laboratory at the Molndal campus of the University of Gothenburg, Sweden. Each round consists of three quality control samples. Results Forty laboratories participated. Twenty-six used INNOTESTenzyme-linked immunosorbent assay kits, 14 used Luminex xMAP with the INNO-BIA AlzBio3 kit (both measure A?-(1-42), P-tau(181P), and T-tau), and 5 used Meso Scale Discovery with the A? triplex (A?N-42, A?N-40, and A?N-38) or T-tau kits. The total coefficients of variation between the laboratories were 13% to 36%. Five laboratories analyzed the samples six times on different occasions. Within-laboratory precisions differed considerably between biomarkers within individual laboratories. Conclusions Measurements of CSF AD biomarkers show large between-laboratory variability, likely caused by factors related to analytical procedures and the analytical kits. Standardization of laboratory procedures and efforts by kit vendors to increase kit performance might lower variability, and will likely increase the usefulness of CSF AD biomarkers.

Mattsson, Niklas; Andreasson, Ulf; Persson, Staffan; Arai, Hiroyuki; Batish, Sat Dev; Bernardini, Sergio; Bocchio-Chiavetto, Luisella; Blankenstein, Marinus A.; Carrillo, Maria C.; Chalbot, Sonia; Coart, Els; Chiasserini, Davide; Cutler, Neal; Dahlfors, Gunilla; Duller, Stefan; Fagan, Anne M.; Forlenza, Orestes; Frisoni, Giovanni B.; Galasko, Douglas; Galimberti, Daniela; Hampel, Harald; Handberg, Aase; Heneka, Michael T.; Herskovits, Adrianna Z.; Herukka, Sanna-Kaisa; Holtzman, David M.; Humpel, Christian; Hyman, Bradley T.; Iqbal, Khalid; Jucker, Mathias; Kaeser, Stephan A.; Kaiser, Elmar; Kapaki, Elisabeth; Kidd, Daniel; Klivenyi, Peter; Knudsen, Cindy S.; Kummer, Markus P.; Lui, James; Llado, Albert; Lewczuk, Piotr; Li, Qiao-Xin; Martins, Ralph; Masters, Colin; McAuliffe, John; Mercken, Marc; Moghekar, Abhay; Molinuevo, Jose Luis; Montine, Thomas J.; Nowatzke, William; O'Brien, Richard; Otto, Markus; Paraskevas, George P.; Parnetti, Lucilla; Petersen, Ronald C.; Prvulovic, David; de Reus, Herman P. M.; Rissman, Robert A.; Scarpini, Elio; Stefani, Alessandro; Soininen, Hilkka; Schroder, Johannes; Shaw, Leslie M.; Skinningsrud, Anders; Skrogstad, Brith; Spreer, Annette; Talib, Leda; Teunissen, Charlotte; Trojanowski, John Q.; Tumani, Hayrettin; Umek, Robert M.; Van Broeck, Bianca; Vanderstichele, Hugo; Vecsei, Laszlo; Verbeek, Marcel M.; Windisch, Manfred; Zhang, Jing; Zetterberg, Henrik; Blennow, Kaj

2013-01-01

369

International quality control survey of neurochemical dementia diagnostics  

Microsoft Academic Search

Currently, neurochemical dementia diagnostics (NDD) are increasingly entering routine clinical neurochemistry, offering improved early and differential diagnosis of dementias. However, there is an obvious lack of standardization in pre-analytical sample handling and systematic quality surveys. Therefore, in this study, 14 laboratories in Germany, Austria, and Switzerland were given aliquots of a human cerebrospinal fluid (CSF) sample, and were asked to

Piotr Lewczuk; Georg Beck; Oliver Ganslandt; Hermann Esselmann; Florian Deisenhammer; Axel Regeniter; Hela-Felicitas Petereit; Hayrettin Tumani; Andreas Gerritzen; Patrick Oschmann; Johannes Schröder; Peter Schönknecht; Klaus Zimmermann; Harald Hampel; Katharina Bürger; Markus Otto; Sabine Haustein; Karin Herzog; Rainer Dannenberg; Ulrich Wurster; Mirko Bibl; Juan Manuel Maler; Udo Reubach; Johannes Kornhuber; Jens Wiltfang

2006-01-01

370

Assuring Quality Control of Clinical Education in Multiple Clinical Affiliates.  

ERIC Educational Resources Information Center

A plan was developed to assure equivalency of clinical education among the medical laboratory technician (MLT) programs affiliated with Sandhills Community College. The plan was designed by faculty to monitor the quality of clinical courses offered by the clinical affiliates. The major strategies were to develop competencies, slide/tape modules, a…

Davis, Judith A.

371

Mitochondrial quality control and Parkinson's disease: a pathway unfolds.  

PubMed

Recent findings from genetic studies suggest that defective mitochondrial quality control may play an important role in the development of Parkinson's disease (PD). Such defects may result in the impairment of neuronal mitochondria, which leads to both synaptic dysfunction and cell death and results in neurodegeneration. Here, we review state-of-the-art knowledge of how pathways affecting mitochondrial quality control might contribute to PD, with a particular emphasis on the molecular mechanisms employed by PTEN-induced putative kinase 1 (PINK1), HtrA2 and Parkin to regulate mitochondrial quality control. PMID:21120708

de Castro, Inês Pimenta; Martins, L Miguel; Loh, Samantha Hui Yong

2011-04-01

372

Quality Assurance Baseline Assessment Report to Los Alamos National Laboratory Analytical Chemistry Operations  

SciTech Connect

This report summarizes observations that were made during a Quality Assurance (QA) Baseline Assessment of the Nuclear Materials Technology Analytical Chemistry Group (NMT-1). The Quality and Planning personnel, for NMT-1, are spending a significant amount of time transitioning out of their roles of environmental oversight into production oversight. A team from the Idaho National Engineering and Environmental Laboratory Defense Program Environmental Surety Program performed an assessment of the current status of the QA Program. Several Los Alamos National Laboratory Analytical Chemistry procedures were reviewed, as well as Transuranic Waste Characterization Program (TWCP) QA documents. Checklists were developed and the assessment was performed according to an Implementation Work Plan, INEEL/EXT-98-00740.

Jordan, R. A.

1998-09-01

373

Supplemental Control for Aircraft Riding Qualities  

NASA Technical Reports Server (NTRS)

The concept of preview control has been applied and proven to be successful in the automotive vehicle. These same concepts are now applied to an aircraft under the assumption that exogenous inputs (wind gust, turbulence, etc. ) can be measured. A supplemental control law for surface deflection is designed to compensate for the loss in performance in the presence of atmospheric disturbances. Fuzzy logic control is employed to handle the nonlinear, time varying characteristics of the disturbance. A methodology to tune the outer loop control parameters is presented.

Williams, Rolanda S.; Ashokkumar, C. R.; Homaifar, Abdollah

1997-01-01

374

40 CFR 81.270 - Northern Arizona Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2013 CFR

...2013-07-01 2013-07-01 false Northern Arizona Intrastate Air Quality Control Region...Control Regions § 81.270 Northern Arizona Intrastate Air Quality Control Region. The Northern Arizona Intrastate Air Quality Control...

2013-07-01

375

40 CFR 81.271 - Central Arizona Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2013 CFR

...2013-07-01 2013-07-01 false Central Arizona Intrastate Air Quality Control Region...Control Regions § 81.271 Central Arizona Intrastate Air Quality Control Region. The Central Arizona Intrastate Air Quality Control...

2013-07-01

376

40 CFR 81.272 - Southeast Arizona Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2013 CFR

...2013-07-01 2013-07-01 false Southeast Arizona Intrastate Air Quality Control Region...Control Regions § 81.272 Southeast Arizona Intrastate Air Quality Control Region. The Southeast Arizona Intrastate Air Quality Control...

2013-07-01

377

40 CFR 81.49 - Southeast Florida Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2013 CFR

...2013-07-01 2013-07-01 false Southeast Florida Intrastate Air Quality Control Region...Control Regions § 81.49 Southeast Florida Intrastate Air Quality Control Region. The Southeast Florida Intrastate Air Quality Control...

2013-07-01

378

40 CFR 81.95 - Central Florida Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2013 CFR

...2013-07-01 2013-07-01 false Central Florida Intrastate Air Quality Control Region...Control Regions § 81.95 Central Florida Intrastate Air Quality Control Region. The Central Florida Intrastate Air Quality Control...

2013-07-01

379

40 CFR 81.96 - West Central Florida Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2013 CFR

... 2013-07-01 false West Central Florida Intrastate Air Quality Control Region...Control Regions § 81.96 West Central Florida Intrastate Air Quality Control Region. The West Central Florida Intrastate Air Quality Control...

2013-07-01

380

40 CFR 81.240 - Northeastern Plains Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2013 CFR

... 2013-07-01 false Northeastern Plains Intrastate Air Quality Control Region...Control Regions § 81.240 Northeastern Plains Intrastate Air Quality Control Region. The Northeastern Plains Intrastate Air Quality Control...

2013-07-01

381

40 CFR 81.67 - Lake Michigan Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2012 CFR

...2012-07-01 2012-07-01 false Lake Michigan Intrastate Air Quality Control...Control Regions § 81.67 Lake Michigan Intrastate Air Quality Control...Control Region has been renamed the Lake Michigan Intrastate Air Quality...

2012-07-01

382

40 CFR 81.67 - Lake Michigan Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2011 CFR

...2011-07-01 2011-07-01 false Lake Michigan Intrastate Air Quality Control...Control Regions § 81.67 Lake Michigan Intrastate Air Quality Control...Control Region has been renamed the Lake Michigan Intrastate Air Quality...

2011-07-01

383

40 CFR 81.67 - Lake Michigan Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2010 CFR

...2010-07-01 2010-07-01 false Lake Michigan Intrastate Air Quality Control...Control Regions § 81.67 Lake Michigan Intrastate Air Quality Control...Control Region has been renamed the Lake Michigan Intrastate Air Quality...

2010-07-01

384

40 CFR 81.201 - Mansfield-Marion Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2010 CFR

... 2009-07-01 false Mansfield-Marion Intrastate Air Quality Control Region...Control Regions § 81.201 Mansfield-Marion Intrastate Air Quality Control Region. The Mansfield-Marion Intrastate Air Quality Control...

2009-07-01

385

Isotopic power supplies for space and terrestrial systems: quality assurance by Sandia National Laboratories  

SciTech Connect

The Sandia National Laboratories participation in Quality Assurance (QA) programs for Radioisotopic Thermoelectric Generators which have been used in space and terrestrial systems over the past 15 years is summarized. Basic elements of the program are briefly described and recognition of assistance from other Sandia organizations is included. Descriptions of the various systems for which Sandia has had the QA responsibility are also presented. In addition, the outlook for Sandia participation in RTG programs for the next several years is noted.

Hannigan, R.L.; Harnar, R.R.

1981-09-01

386

Improvement of interpretation in cystic fibrosis clinical laboratory reports: longitudinal analysis of external quality assessment data  

PubMed Central

Participation in external quality assessment (EQA) is a key element of quality assurance in medical laboratories. In genetics EQA, both genotyping and interpretation are assessed. We aimed to analyse changes in the completeness of interpretation in clinical laboratory reports of the European cystic fibrosis EQA scheme and to investigate the effect of the number of previous participations, laboratory accreditation/certification status, setting and test volume. We distributed similar versions of mock clinical cases to eliminate the influence of the difficulty of the clinical question on interpretation performance: a cystic fibrosis patient (case 1) and a cystic fibrosis carrier (case 2). We then performed a retrospective longitudinal study of reports over a 6-year period from 298 participants for case 1 (2004, 2008, 2009) and from 263 participants for case 2 (2006, 2008, 2009). The number of previous participations had a positive effect on the interpretation score (P<0.0001), whereas the laboratory accreditation/certification status, setting and test volume had no effect. Completeness of interpretation improved over time. The presence of the interpretation element ‘requirement for studying the parents to qualify the genotype' increased most (from 49% in 2004 to 93% in 2009). We still observed room for improvement for elements that concerned offering testing for familial mutations in relatives and prenatal/preimplantation diagnosis (16% and 24% omission, respectively, for case 1 in 2009). Overall, regular participation in external quality assessment contributes to improved interpretation in reports, with potential value for quality of care for patients and families by healthcare professionals involved in genetic testing.

Berwouts, Sarah; Girodon, Emmanuelle; Schwarz, Martin; Stuhrmann, Manfred; Morris, Michael A; Dequeker, Elisabeth

2012-01-01

387

Mesh quality control for multiply-refined tetrahedral grids  

NASA Technical Reports Server (NTRS)

A new algorithm for controlling the quality of multiply-refined tetrahedral meshes is presented in this paper. The basic dynamic mesh adaption procedure allows localized grid refinement and coarsening to efficiently capture aerodynamic flow features in computational fluid dynamics problems; however, repeated application of the procedure may significantly deteriorate the quality of the mesh. Results presented show the effectiveness of this mesh quality algorithm and its potential in the area of helicopter aerodynamics and acoustics.

Biswas, Rupak; Strawn, Roger

1994-01-01

388

Water quality laboratories in Colombia: A GIS-based study of urban and rural accessibility.  

PubMed

The objective of this study was to quantify sample transportation times associated with mandated microbiological monitoring of drinking-water in Colombia. World Health Organization Guidelines for Drinking-Water Quality recommend that samples spend no more than 6h between collection and analysis in a laboratory. Census data were used to estimate the minimum number of operational and surveillance samples required from piped water supplies under national regulations. Drive-times were then computed from each supply system to the nearest accredited laboratory and translated into sample holding times based on likely daily monitoring patterns. Of 62,502 surveillance samples required annually, 5694 (9.1%) were found to be more than 6h from the nearest of 278 accredited laboratories. 612 samples (1.0%) were more than 24hours' drive from the nearest accredited laboratory, the maximum sample holding time recommended by the World Health Organization. An estimated 30% of required rural samples would have to be stored for more than 6h before reaching a laboratory. The analysis demonstrates the difficulty of undertaking microbiological monitoring in rural areas and small towns from a fixed laboratory network. Our GIS-based approach could be adapted to optimise monitoring strategies and support planning of testing and transportation infra-structure development. It could also be used to estimate sample transport and holding times in other countries. PMID:24747256

Wright, Jim; Liu, Jing; Bain, Robert; Perez, Andrea; Crocker, Jonny; Bartram, Jamie; Gundry, Stephen

2014-07-01

389

Control scheme of hybrid active filter for power quality improvement  

Microsoft Academic Search

A control scheme of hybrid active filter with integrated series active filter and parallel passive filter for power quality improvement is presented. The system is capable of compensating the current and voltage harmonics and voltage sag in distribution system. The line current is controlled to be sinusoidal in phase with mains voltage and load terminal voltage is controlled to be

Bor-Ren Lin; Chun-Hao Huang; Bor-Ren Yang

2002-01-01

390

Systems for Continuous Water Quality Control in a Flow  

Microsoft Academic Search

The advantages of systems for continuous water quality control in a flow over a traditional control system based on sampling for the environmental monitoring and process control of aqueous media at regular intervals are considered. General principles for the design of systems of this kind are discussed using the development of shipborne ecoanalytical complexes as an example. Data on the

A. L. Moskvin; L. N. Moskvin; I. A. Ardashnikova

2000-01-01

391

Quality control of polymer production processes  

Microsoft Academic Search

For the polymer production industries, the competitive edge will come from the technology that excels in controlling the polymer properties in a consistent way over the entire plant and in maximizing the production performance while keeping safety regulations. Based on the experience in applying advanced process control and scheduling schemes to industrial polyolefin polymerization plants, the state of the art

Masahiro Ohshima; Masataka Tanigaki

2000-01-01

392

Relational Control and Relationship Quality in Psychotherapy.  

ERIC Educational Resources Information Center

Certain interactional theorists propose that for counseling/psychotherapy to be effective, the therapist must control the definition of the therapy relationship. Although the relationship between patterns of relational dominance/control in counseling and counseling outcome seems reasonably well established, little is known of the relationship…

Lichtenberg, James W.; And Others

393

Quality control of pumps for nuclear applications  

Microsoft Academic Search

The new generations of primary pumps for nuclear reactors of the PWR ; (Westinghouse) type have developed rapidly to come to the present day pump sets ; consisting of a traditional electric motor driving a controlled leakage pump, the ; ratings contmuing to increase. Present control and inspection techniques have ; followed and even preceded this development. The article reviews

Vockovic

1973-01-01

394

Ultrasonic quality control methods for spot-welded joints  

Microsoft Academic Search

Spot resistance welding is the most popular method of connecting the steel structures of automotive vehicles. At a time when quality requirements relating to finished goods are higher and higher, welded joints must undergo precise controls in order to assure the highest safety standards possible. Ultrasonic methods enable quick and accurate assessment of any welded joint's quality, and at the

Andrzej Ambroziak; Roman G. Maev; Marcin Korzeniowski; Pawe? Kustro?

2011-01-01

395

115. QUALITY CONTROL BOARD FOR MAINTENANCE AND INSPECTION AT SOUTH ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

115. QUALITY CONTROL BOARD FOR MAINTENANCE AND INSPECTION AT SOUTH SIDE OF MECHANICAL AND ELECTRICAL ROOM (110), LSB (BLDG. 770), FACING WEST ON EXTERIOR WALL OF QUALITY ASSURANCE ROOM (106A) - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 West, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

396

Quantitative quality control in microarray image processing and data acquisition  

Microsoft Academic Search

A new integrated image analysis package with quanti- tative quality control schemes is described for cDNA microarray technology. The package employs an itera- tive algorithm that utilizes both intensity characteristics and spatial information of the spots on a microarray image for signal-background segmentation and defines five quality scores for each spot to record irreg- ularities in spot intensity, size and

Xujing Wang; Soumitra Ghosh; Sun-Wei Guo

2001-01-01

397

Water-quality estimation and control in streams  

Microsoft Academic Search

In this paper a methodology is given for the process of water-quality estimation and control in streams using a systems approach. The proposed procedure is based on the stream water quality model developed by Hassan et at. (1981). A linear observer is designed that can be used to estimate the unobservable states of the system. These states represent the concentration

MOHAMED FAHIM HASSAN

1986-01-01

398

QE (quality versus engineering) evolution in pursuit of a quality goal—a methodological foundation of quality control  

Microsoft Academic Search

Japan has achieved a high standard of the practice of quality control in manufacturing industries. There are many factors which have contributed to this ranging from the organizational climate of Japan to purely scientific and technological aspects. From the viewpoint of industrial engineering, a wide practice of quality evolution (‘ Hinshitsu-Tenkai’ in Japanese) is one of the major activities which

OSAMU FURUKAWA; HIDEOMI IKESHOJI; AKIRA OHMORI

1983-01-01

399

The 5th Annual NASA Spacecraft Control Laboratory Experiment (SCOLE) Workshop, part 2  

NASA Technical Reports Server (NTRS)

A collection of papers from the workshop are presented. The topics addressed include: the modeling, systems identification, and control synthesis for the Spacecraft Control Laboratory Experiment (SCOLE) configuration.

Taylor, Lawrence W., Jr. (compiler)

1990-01-01

400

[The medical gas central supply system and its quality control].  

PubMed

This paper introduces the principles of the medical gas central supply system and its structure, Classification, standards, flow chart and its advantages, and its quantity guarantee and quality control. PMID:16104270

Zhong, Yin-bao; Qi, Yue-guo; Tang, Chao

2002-09-01

401

Mössbauer spectroscopy and quality control in ferrate technology  

NASA Astrophysics Data System (ADS)

This paper describes some prospective reactants for the ferrate technology of water treatment, the ways of their industrial production and the application of the Mössbauer spectroscopy for their quality control.

Dedushenko, S. K.; Perfiliev, Yu. D.; Kulikov, L. A.

2013-04-01

402

QC (Quality Control) for Stationary Source Particle Size Measurements.  

National Technical Information Service (NTIS)

The paper discusses quality control (QC) for stationary source particle size measurements. Traditional QC methodology has generally involved retrospective evaluation of existing products (e.g., environmental data). Rather than identify failures, it is now...

G. L. Johnson C. E. Tatsch W. M. Yeager

1986-01-01

403

QC (QUALITY CONTROL) FOR STATIONARY SOURCE PARTICLE SIZE MEASUREMENTS  

EPA Science Inventory

The paper discusses quality control (QC) for stationary source particle size measurements. Traditional QC methodology has generally involved retrospective evaluation of existing products (e.g., environmental data). Rather than identify failures, it is now increasingly possible an...

404

Evaluation of Department of Defense Policies for Subcontractor Quality Control.  

National Technical Information Service (NTIS)

During the current period of time when emphasis within DoD procurement is on efficiency, subcontractor quality control procedures are being considered as a possible means of improvement. The document explores possible means of improving the efficiency of ...

J. C. Dondlinger

1972-01-01

405

Control Charts as a Tool in Data Quality Improvement.  

National Technical Information Service (NTIS)

Control-charting has been successfully applied to two National Highway Traffic Safety Administration data systems to help improve and assure the quality of their data. This paper describes the methods used, illustrates the approach through various example...

C. E. Pierchala J. Surti

1999-01-01

406

Quality Control Analysis. Part III. Concrete and Concrete Aggregates.  

National Technical Information Service (NTIS)

This is the third and last report on the Quality Control Analysis of highway construction materials. It deals with the statistical evaluation of data from several construction projects to determine variability of 'Slump' and of aggregates. The analysis in...

S. C. Shah

1966-01-01

407

46 CFR 164.120-11 - Production quality control requirements.  

Code of Federal Regulations, 2013 CFR

...HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL MATERIALS Fire Retardant Resins for Lifeboats and Rescue Boats § 164.120-11 Production quality control requirements. The...

2013-10-01

408

Aquatic macroinvertebrates and water quality of Sandia Canyon, Los Alamos National Laboratory, November 1993--October 1994  

SciTech Connect

The Ecological Studies Team (EST) of ESH-20 at Los Alamos National Laboratory (LANL) has collected samples from the stream within Sandia Canyon since the summer of 1990. These field studies gather water quality measurements and collect aquatic macroinvertebrates from permanent sampling sites. Reports by Bennett (1994) and Cross (1994) discuss previous EST aquatic studies in Sandia Canyon. This report updates and expands those findings. EST collected water quality data and aquatic macroinvertebrates at five permanent stations within the canyon from November 1993 through October 1994. The two upstream stations are located below outfalls that discharge industrial and sanitary waste effluent into the stream, thereby maintaining year-round flow. Some water quality parameters are different at the first three stations from those expected of natural streams in the area, indicating degraded water quality due to effluent discharges. The aquatic habitat at the upper stations has also been degraded by sedimentation and channelization. The macroinvertebrate communities at these stations are characterized by low diversities and unstable communities. In contrast, the two downstream stations appear to be in a zone of recovery, where water quality parameters more closely resemble those found in natural streams of the area. The two lower stations have increased macroinvertebrate diversity and stable communities, further indications of downstream water quality improvement.

Cross, S.

1995-08-01

409

Achieving indoor air quality through contaminant control  

SciTech Connect

Federal laws outlining industry`s responsibilities in creating a healthy, hazard-free workspace are well known. OSHA`s laws on interior air pollution establish threshold limit values (TLVs) and permissible exposure limits (PELs) for more than 500 potentially hazardous substances found in manufacturing operations. Until now, OSHA has promulgated regulations only for the manufacturing environment. However, its recently-proposed indoor air quality (IAQ) ruling, if implemented, will apply to all workspaces. It regulates IAQ, including environmental tobacco smoke, and requires employers to write and implement IAQ compliance plans.

Katzel, J.

1995-07-10

410

Requirements for quality control of analytical data for the Environmental Restoration Program  

SciTech Connect

The Environmental Restoration (ER) Program was established for the investigation and remediation of inactive US Department of Energy (DOE) sites and facilities that have been declared surplus in terms of their previous uses. The purpose of this document is to Specify ER requirements for quality control (QC) of analytical data. Activities throughout all phases of the investigation may affect the quality of the final data product, thus are subject to control specifications. Laboratory control is emphasized in this document, and field concerns will be addressed in a companion document Energy Systems, in its role of technical coordinator and at the request of DOE-OR, extends the application of these requirements to all participants in ER activities. Because every instance and concern may not be addressed in this document, participants are encouraged to discuss any questions with the ER Quality Assurance (QA) Office, the Analytical Environmental Support Group (AESG), or the Analytical Project Office (APO).

Engels, J.

1992-12-01

411

Indoor air quality: Sources and control  

SciTech Connect

The nature and origin of major classes of indoor pollutants is discussed. Measures to control such pollutants are also discussed. Attention is focused on what perhaps is the major indoor pollutant in the developed countries radon and its progeny. (AIP)

Sextro, R.G.; Nero, A.V.; Grimsrud, D.T.

1985-11-25

412

[Laboratory control in diagnosis and treatment of infective endocarditis].  

PubMed

Infectious endocarditis is caused by a wide variety of microorganisms. Etiological diagnosis depends either on direct methods, directed to the detection and isolation of the causative organisms, or serological methods. Blood cultures remain as the best method for the diagnosis of bacterial endocarditis. Blood culture technology has changed due to the appearance of new automatic continuous monitoring systems which shorten the detection time. Endocarditis with a negative blood culture has decreased below 5% because of new blood culture systems, new serological methods and molecular technology. The control of antimicrobial therapy in endocarditis must be performed by expert laboratories. A minimal bactericidal concentration, serum levels of antimicrobials and the serum bactericidal test are the most useful parameters. Their execution requires the use of strict protocols and interpretation must be carried out with an expert in clinical microbiology and infectious diseases. PMID:9658945

Pascual, A; Perea, E J

1998-01-01

413

Laboratory Experiments on the Control of Cyclops Transmitting Guinea Worm  

PubMed Central

Infection with the guinea worm (Dracunculus medinensis) affects millions of people living in rural areas in certain parts of the world. Usually, the standard of living is low and elaborate control measures would not be feasible. In this study, various insecticidal and molluscicidal compounds were tested in the laboratory for their toxicity to the intermediate hosts, namely, various species of cyclops, which often live in sources of potable water, such as step-wells, cisterns and ponds. Cheapness, low toxicity to mammals and ease of application, in conjunction with effectiveness against cyclops, are primary requisites for any compound accepted for widespread use. Abate, an insecticide, has been shown to be particularly promising in these respects. The timing and mode of application of compounds toxic to cyclops in various endemic regions are discussed.

Muller, Ralph

1970-01-01

414

Controlling formaldehyde exposures in an academic gross anatomy laboratory.  

PubMed

This report describes efforts over a more than a 15-year period to improve air quality and reduce exposures to formaldehyde during anatomical dissections at the Yale University School of Medicine, including first-year medical student gross anatomy classes. During this time, a number of steps were taken to improve general ventilation system efficiency and work practices in the original facility. Subsequently, during the design phase for a new research and teaching building, a new anatomical laboratory was planned to incorporate 42 individually ventilated dissection tables. The tables were customized from a commercially available design to operate at lower volumetric airflow rates while still providing a high degree of formaldehyde containment. Air monitoring performed throughout this time period showed progressive reductions in formaldehyde exposure as ventilation modifications were made. However, significant reductions only occurred after the installation of the ventilated tables. Personal and area exposure monitoring during thoracic and abdominal dissections now show a five- to tenfold reduction in formaldehyde exposure compared to previous operations, with exposures consistently below 0.1 ppm. PMID:24521062

Klein, Robert C; King, Cathleen; Castagna, Paula

2014-03-01

415

Sandia National Laboratories Advanced Simulation and Computing (ASC) Software Quality Plan. Part 2, Mappings for the ASC software quality engineering practices. Version 1.0.  

SciTech Connect

The purpose of the Sandia National Laboratories Advanced Simulation and Computing (ASC) Software Quality Plan is to clearly identify the practices that are the basis for continually improving the quality of ASC software products. The plan defines the ASC program software quality practices and provides mappings of these practices to Sandia Corporate Requirements CPR 1.3.2 and 1.3.6 and to a Department of Energy document, 'ASCI Software Quality Engineering: Goals, Principles, and Guidelines'. This document also identifies ASC management and software project teams responsibilities in implementing the software quality practices and in assessing progress towards achieving their software quality goals.

Ellis, Molly A.; Heaphy, Robert; Sturtevant, Judith E.; Hodges, Ann Louise; Boucheron, Edward A.; Drake, Richard Roy; Forsythe, Christi A.; Schofield, Joseph Richard, Jr.; Pavlakos, Constantine James; Williamson, Charles Michael; Edwards, Harold Carter

2005-01-01

416

A dynamic quality control phantom for radionuclide cardiology.  

PubMed

A three-dimensional dynamic cardiac phantom suitable for quality control of equilibrium gated nuclear cardiographic procedures is described. Its flexible microprocessor based design provides an absolute standard for ejection fraction determination, ventricular volume quantitation, and physiologically gated single photon emission computed tomography. The cost of the phantom is comparable to that of commercially available phantoms suitable for ejection fraction quality control alone. PMID:3485237

Sloboda, R S; Hardie, D I; Schmid, M; Morris, P B; Hughes, J; Malik, M H

1986-01-01

417

Use of the selective linogram in cardiac tomography quality control  

Microsoft Academic Search

Background  Quality control for detection of patient motion is essential in tomographic myocardial imaging. Despite significant limitations,\\u000a the summation image or conventional “linogram” has long been advocated as a useful image in the detection of vertical motion.\\u000a In this study a new quality control image entitled the “selective linogram” is proposed to replace the summation image in\\u000a routine cardiac single-photon emission

Jerold W. Wallis

1995-01-01

418

Manned Space-laboratories Control Center (MSCC) operations concept  

NASA Technical Reports Server (NTRS)

The initiation of the (German-) nationally funded control center for manned spaceflight operations triggered by the invitation of President Reagan to ESA, Japan, and Canada in 1984 to join the International Space Station Freedom Program is recalled. The requirements for a Manned Space-Laboratories Control Center (MSCC) as defined at the beginning of the planning and construction process in 1987 and the resulting modifications during the various programmatic scenario changes on NASA and ESA side between 1987 and now are presented. The validity of the original requirements with respect to the current scenario, which asks for a logical evolution from the execution of the D-2 mission in January 1993 via the European Columbus Precursor flights (in particular the E-1 mission) towards Columbus Attached Laboratory (APM)-operations by the end of this century are discussed. The resulting tasks of the MSCC for the various missions, the current configuration, and the ensuing operations concept leading from a more centralized concept for D-2 towards a decentralized payload operations concept for the APM and the implications with respect to European and International interfaces are presented. The planned Columbus MSCC facility architecture and its expected modifications introduced by the ESA Ministerial Conference in Munich (Nov. 1991) and follow-on discussions are briefly addressed. The last chapter outlines the planned services to be provided by the MSCC to the decentralized User (experimenter) community. Issues like decentralized mission planning on executional level, command validation, data flow coordination, archiving services, and telescience capabilities are highlighted from a MSCC point of view.

Kehr, Joachim

1993-01-01

419

HANDBOOK: QUALITY ASSURANCE/QUALITY CONTROL (QA/QC) PROCEDURES FOR HAZARDOUS WASTE INCINERATION  

EPA Science Inventory

Resource Conservation and Recovery Act regulations for hazardous waste incineration require trial burns by permit applicants. uality Assurance Project Plan (QAPjP) must accompany a trial burn plan with appropriate quality assurance/quality control procedures. uidance on the prepa...

420

Quality Assurance and Quality Control Practices for Rehabilitation of Sewer and Water Mains  

EPA Science Inventory

As part of the US Environmental Protection Agency (EPA)?s Aging Water Infrastructure Research Program, several areas of research are being pursued, including a review of quality assurance and quality control (QA/QC) practices and acceptance testing during the installation of reha...

421

Quality Assurance and Quality Control Practices For Rehabilitation of Sewer and Water Mains  

EPA Science Inventory

As part of the US Environmental Protection Agency (EPA)?s Aging Water Infrastructure Research Program, several areas of research are being pursued including a review of quality assurance and quality control (QA/QC) practices and acceptance testing during the installation of rehab...

422

Multi-Agent Architecture with Support to Quality of Service and Quality of Control  

NASA Astrophysics Data System (ADS)

Multi Agent Systems (MAS) are one of the most suitable frameworks for the implementation of intelligent distributed control system. Agents provide suitable flexibility to give support to implied heterogeneity in cyber-physical systems. Quality of Service (QoS) and Quality of Control (QoC) parameters are commonly utilized to evaluate the efficiency of the communications and the control loop. Agents can use the quality measures to take a wide range of decisions, like suitable placement on the control node or to change the workload to save energy. This article describes the architecture of a multi agent system that provides support to QoS and QoC parameters to optimize de system. The architecture uses a Publish-Subscriber model, based on Data Distribution Service (DDS) to send the control messages. Due to the nature of the Publish-Subscribe model, the architecture is suitable to implement event-based control (EBC) systems. The architecture has been called FSACtrl.

Poza-Luján, Jose-Luis; Posadas-Yagüe, Juan-Luis; Simó-Ten, Jose-Enrique

423

Fuzzy control in image qualities of holographic optical elements (HOE)  

NASA Astrophysics Data System (ADS)

A fuzzy control model in image formation qualities of holograms manufactured in dichromated gelatin; Agfa 8E75 and other holographic recording material are described. A new model based on the fuzzy set theory is presented to control spectral shifting from the frequency of construction laser beam to the frequency of request. We are concerned with new simplified procedures inserted in ordinary hologram manufacturing process. From the modulation mechanism in these holograms we seize the intrinsic qualities and our model of fuzzy set analysis show to produce good general agreement with the experimentally measured image formation qualities.

Chang, Rong-Seng; Lin, Chern-Sheng

1994-05-01

424

Experience with ISO quality control in assisted reproductive technology.  

PubMed

Assisted reproductive technology (ART) programs are complex organizations requiring the integration of multiple disciplines. ISO 9001:2008 is a quality management system that is readily adaptable to an ART program. The value that ISO brings to the entire organization includes control of documents, clear delineation of responsibilities of staff members, documentation of the numerous processes and procedures, improvement in tracking and reducing errors, and overall better control of systems. A quality ART program sets quality objectives and monitors their progress. ISO provides a sense of transparency within the organization and clearer understanding of how service is provided to patients. Most importantly, ISO provides the framework to allow for continual improvement. PMID:24112531

Alper, Michael M

2013-12-01

425

A Remote Laboratory Platform for Electrical Drive Control Using Programmable Logic Controllers  

Microsoft Academic Search

Many teaching institutions worldwide are working on distance learning applications. In this field, remote laboratories are enabling intensive use of university facilities, while aiding the work of professors and students. The present paper introduces a platform designed to be used in industrial automation practical work. The platform is communicable through the Internet, includes programmable logic controllers that can be programmed

Coia Ferrater-Simon; Lluís Molas-Balada; Oriol Gomis-Bellmunt; Noelia Lorenzo-Martinez; Oriol Bayo-Puxan; Roberto Villafafila-Robles

2009-01-01

426

Multivariate Quality Control Chart for Autocorrelated Processes  

Microsoft Academic Search

Traditional multivariate statistical process control (SPC) techniques are based on the assumption that the successive observation vectors are independent. In recent years, due to automation of measurement and data collection systems, a process can be sampled at higher rates, which ultimately leads to autocorrelation. Consequently, when the autocorrelation is present in the data, it can have a serious impact on

A. A. Kalgonda; S. R. Kulkarni

2004-01-01

427

Air quality and pollution control in Taiwan  

NASA Astrophysics Data System (ADS)

Due to limited land and great emphasis on economic growth in the past, Taiwan has an extremely heavy environmental burden. Population density, factory density, as well as densities of motor vehicles are several times higher than those in the United States and Japan. According to the statistics of 1991, the Pollutant Standards Index (PSI) fell mostly in the "moderate" category, i.e., in the range of 50-100. There were 16.25% of the monitored days with PSI above 100, and 0.51% with PSI beyond 200. Suspended particulates were the major pollutant responsible for PSI above 100, followed by carbon monoxide, ozone, and sulfur dioxide. The measures adopted to control air pollution can be divided into four categories, namely law and regulations, control measures on stationary sources, mobile sources and construction projects. The latest amended Air Pollution Control Act was promulgated on 1 February 1992. Several major revisions were introduced to make the amended Act much more stringent than the 1982 amendment, especially on the offenses likely to endanger public health and welfare. In regard to stationary sources, a permit system was enacted to regulate the establishment and alteration of stationary sources. Designated stationary sources are required to be equipped with automatic monitoring facilities. An inspection and enforcement program have expanded to cover more than 10,000 factories. Major control measures for motor vehicles include introducing stringent emission standards for gasoline-fueled vehicles and diesel cars, setting up ratification and approval program for new vehicle model, promoting the inspection/maintenance program on in-used motorcycles and encouraging the use of unleaded and low sulfur fuels. In order to control the pollution caused by construction work, constructors are required to use low-pollution machinery and engineering methods and incorporate pollution prevention into the construction budget.

Fang, Shu-Hwei; Chen, Hsiung-Wen

428

Software quality assurance and software safety in the Biomed Control System  

SciTech Connect

The Biomed Control System is a hardware/software system used for the delivery, measurement and monitoring of heavy-ion beams in the patient treatment and biology experiment rooms in the Bevalac at the Lawrence Berkeley Laboratory (LBL). This paper describes some aspects of this system including historical background philosophy, configuration management, hardware features that facilitate software testing, software testing procedures, the release of new software quality assurance, safety and operator monitoring. 3 refs.

Singh, R.P.; Chu, W.T.; Ludewigt, B.A.; Marks, K.M.; Nyman, M.A.; Renner, T.R.; Stradtner, R.

1989-10-31

429

Research on Multi-dimension Model of Collaborative Quality Control in Manufacturing Network  

Microsoft Academic Search

Based on analyzing quality chain environment and product quality formation processes in manufacturing network, the author proposes a collaborative product quality control mode and establishes a multi-dimension collaborative quality control model in this paper. The model has three dimensions: process quality, network organization and quality information. This paper focuses on the key contents of each dimension which includes process quality

Wei Guo; Haipeng Liang; Lei Wang; Dongai Wang; Jie Lv

2010-01-01

430

[Quality control in pathological anatomy: 10 years' experience].  

PubMed

The quality assurance scheme in use at the Section of Anatomic Pathology of the University of Bologna-Bellaria Hospital is described. Since 1992 a quality assurance (QA) scheme has been set up in this Institution. The scheme and results have been reported in this same Journal previously 1-3: here are reported the changes to the scheme that have intervened in the last four years. All data collected from January 1999 to December 2002 have been reviewed for monitoring the laboratory performance. Emphasis has been given to changes that have been introduced recently to improve QA. PMID:14577200

Collina, G; Caprara, G; Di Tommaso, L

2003-08-01

431

Radiation control program at the Donald W. Douglas Laboratories  

Microsoft Academic Search

From third Health Physics Society midyear topical symposium; Los ; Angeles, California, USA (29 Jan 1969). See CONF-690103P1. The McDonnell ; Douglas Astronautics Company built and operates the Donald W. Douglas ; Laboratories at Richland, Washington. The 57,600 ft² facility is located ; on a 112 acre site. One wing of this multipurpose laboratory houses a ; radioisotope laboratory and

M. L. Smith; C. A. Willis

1972-01-01

432

Quality of the clinical laboratory department in a specialized hospital in Alexandria, Egypt.  

PubMed

Assessment and improvement of turnaround times (TAT) as well as customer satisfaction is essential for laboratory quality management. This study in a specialized hospital in Alexandria, Egypt measured the current TAT for outpatient department bilirubin samples and evaluated the satisfaction of physicians with aspects of clinical laboratory services. While the mean TAT for 110 bilirubin tests [58.1 (SD 31.8) min] was within the College of American Pathologists' benchmark, the 90th percentile was long (96.7 min); 62.7% of tests were reported within 60 min. The mean overall satisfaction score of physicians (range 1-5) was 3.46 (SD 0.49). The highest satisfaction rating was for staff courtesy while the lowest ratings were for laboratory management responsiveness, outpatient stat TAT and critical value notification. Quality or reliability of results was judged by physicians as the most important factor (32.3%), followed by routine test TAT (18.5%). Further analysis of the different steps of the TAT would be helpful and follow-up through examining outliers is recommended PMID:23520910

Elhoseeny, T A; Mohammad, E K

2013-01-01

433

Quality control assessment of influenza and RSV testing in Europe: 2000-01 season.  

PubMed

The Quality Control Assessment (QCA) was initiated to evaluate the quality of the influenza and respiratory syncytial virus (RSV) testing in the national reference centres belonging to the European Influenza Surveillance Scheme (EISS) network. Samples were coded and sent in two panels of 12 samples within a two week interval to 16 laboratories during the 2000-01 winter season. The antibodies titration by HI test was reported by 60% of the laboratories (n=16), and the results were correct for 56% of them. One false detection of influenza B antibodies was reported by one laboratory, and for the others the sensitivity varied widely. The sensitivity of the tests for the detection of influenza virus varied for A(H3N2) from 10 to 100,000 TCID50/ml. The influenza A subtyping was performed by 87% of the laboratories, and 31% gave correct results. The characterisation of the variants was undertaken by six laboratories and half of them fully achieved it. Fifty six percent of the laboratories used RT-PCR for the diagnosis; the results were specific and the sensitivity equivalent to the cell culture. PMID:12631989

Valette, M; Aymard, M

2002-11-01

434

VIRTUAL QUALITY MANAGEMENT: SIMULATIVE EVALUATION OF QUALITY CONTROL CHARTS BY USE OF QUALITY ORIENTATED PROCESS MODELS  

Microsoft Academic Search

Nowadays innovative processes and process chains are optimized within the planning stage for maximum output. But normally quality management techniques are not scheduled at that stage. They are not realized before the production line is set up and mass production starts. For this reason the production start-up is delayed seriously and high additional efforts are necessary. Virtual Quality Management (vQM)

Albert Weckenmann; Martin Bookjans

435

Laboratory transferability of optimally shaped laser pulses for quantum control.  

PubMed

Optimal control experiments can readily identify effective shaped laser pulses, or "photonic reagents," that achieve a wide variety of objectives. An important additional practical desire is for photonic reagent prescriptions to produce good, if not optimal, objective yields when transferred to a different system or laboratory. Building on general experience in chemistry, the hope is that transferred photonic reagent prescriptions may remain functional even though all features of a shaped pulse profile at the sample typically cannot be reproduced exactly. As a specific example, we assess the potential for transferring optimal photonic reagents for the objective of optimizing a ratio of photoproduct ions from a family of halomethanes through three related experiments. First, applying the same set of photonic reagents with systematically varying second- and third-order chirp on both laser systems generated similar shapes of the associated control landscape (i.e., relation between the objective yield and the variables describing the photonic reagents). Second, optimal photonic reagents obtained from the first laser system were found to still produce near optimal yields on the second laser system. Third, transferring a collection of photonic reagents optimized on the first laser system to the second laser system reproduced systematic trends in photoproduct yields upon interaction with the homologous chemical family. These three transfers of photonic reagents are demonstrated to be successful upon paying reasonable attention to overall laser system characteristics. The ability to transfer photonic reagents from one laser system to another is analogous to well-established utilitarian operating procedures with traditional chemical reagents. The practical implications of the present results for experimental quantum control are discussed. PMID:24559348

Moore Tibbetts, Katharine; Xing, Xi; Rabitz, Herschel

2014-02-21

436

CRN5EXP: Expert system for statistical quality control  

NASA Technical Reports Server (NTRS)

The purpose of the Expert System CRN5EXP is to assist in checking the quality of the coils at two very important mills: Hot Rolling and Cold Rolling in a steel plant. The system interprets the statistical quality control charts, diagnoses and predicts the quality of the steel. Measurements of process control variables are recorded in a database and sample statistics such as the mean and the range are computed and plotted on a control chart. The chart is analyzed through patterns using the C Language Integrated Production System (CLIPS) and a forward chaining technique to reach a conclusion about the causes of defects and to take management measures for the improvement of the quality control techniques. The Expert System combines the certainty factors associated with the process control variables to predict the quality of the steel. The paper presents the approach to extract data from the database, the reason to combine certainty factors, the architecture and the use of the Expert System. However, the interpretation of control charts patterns requires the human expert's knowledge and lends to Expert Systems rules.

Hentea, Mariana

1991-01-01

437

40 CFR 81.102 - Metropolitan Quad Cities Interstate Air Quality Control Region.  

Code of Federal Regulations, 2010 CFR

... 2010-07-01 false Metropolitan Quad Cities Interstate Air Quality Control Region...Control Regions § 81.102 Metropolitan Quad Cities Interstate Air Quality Control Region. The Metropolitan Quad Cities Interstate Air Quality...

2010-07-01

438

40 CFR 81.102 - Metropolitan Quad Cities Interstate Air Quality Control Region.  

Code of Federal Regulations, 2010 CFR

... 2009-07-01 false Metropolitan Quad Cities Interstate Air Quality Control Region...Control Regions § 81.102 Metropolitan Quad Cities Interstate Air Quality Control Region. The Metropolitan Quad Cities Interstate Air Quality...

2009-07-01

439

30 CFR 28.32 - Proposed quality control plans; approval by MSHA.  

Code of Federal Regulations, 2013 CFR

...2013-07-01 2013-07-01 false Proposed quality control plans; approval by MSHA. 28.32...PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.32 Proposed quality control plans; approval by MSHA. (a)...

2013-07-01

440

42 CFR 84.42 - Proposed quality control plans; approval by the Institute.  

Code of Federal Regulations, 2013 CFR

...2013-10-01 2013-10-01 false Proposed quality control plans; approval by the Institute...APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Quality Control § 84.42 Proposed quality control plans; approval by the...

2013-10-01

441

22 CFR 96.39 - Information disclosure and quality control practices.  

Code of Federal Regulations, 2013 CFR

... Information disclosure and quality control practices. 96...Disclosure, Fee Practices, and Quality Control Policies and Practices... Information disclosure and quality control practices. ...country of origin and the usual costs associated with their...

2013-04-01

442

40 CFR 81.169 - Helena Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2013 CFR

...Helena Intrastate Air Quality Control Region. 81.169 Section 81.169 Protection of Environment ENVIRONMENTAL PROTECTION... Designation of Air Quality Control Regions § 81.169 Helena Intrastate Air Quality Control...

2013-07-01

443

40 CFR 81.63 - Metropolitan Fort Smith Interstate Air Quality Control Region.  

Code of Federal Regulations, 2010 CFR

...2010-07-01 false Metropolitan Fort Smith Interstate Air Quality Control Region...Regions § 81.63 Metropolitan Fort Smith Interstate Air Quality Control Region. The Metropolitan Fort Smith Interstate Air Quality Control...

2010-07-01

444

40 CFR 81.63 - Metropolitan Fort Smith Interstate Air Quality Control Region.  

Code of Federal Regulations, 2010 CFR

...2009-07-01 false Metropolitan Fort Smith Interstate Air Quality Control Region...Regions § 81.63 Metropolitan Fort Smith Interstate Air Quality Control Region. The Metropolitan Fort Smith Interstate Air Quality Control...

2009-07-01

445

40 CFR 81.149 - Northern Coastal Plain Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2013 CFR

...2013-07-01 false Northern Coastal Plain Intrastate Air Quality Control Region...Regions § 81.149 Northern Coastal Plain Intrastate Air Quality Control Region. The Northern Coastal Plain Intrastate Air Quality Control...

2013-07-01

446

40 CFR 81.152 - Southern Coastal Plain Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2013 CFR

...2013-07-01 false Southern Coastal Plain Intrastate Air Quality Control Region...Regions § 81.152 Southern Coastal Plain Intrastate Air Quality Control Region. The Southern Coastal Plain Intrastate Air Quality Control...

2013-07-01

447

40 CFR 81.16 - Metropolitan Denver Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2010 CFR

...Designation of Air Quality Control Regions § 81.16 Metropolitan Denver Intrastate Air Quality Control Region. The Metropolitan Denver Intrastate Air Quality Control Region (Colorado) consists of...as defined in section 302(f) of the Clean Air Act,...

2010-07-01

448

40 CFR 81.88 - Billings Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2010 CFR

...Intrastate Air Quality Control Region. The Metropolitan Billings Intrastate Air Quality Control Region (Montana) has been renamed...Intrastate Air Quality Control Region and consists of the territorial...as defined in section 302(f) of the Clean Air Act,...

2009-07-01

449

40 CFR 81.88 - Billings Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2010 CFR

...Intrastate Air Quality Control Region. The Metropolitan Billings Intrastate Air Quality Control Region (Montana) has been renamed...Intrastate Air Quality Control Region and consists of the territorial...as defined in section 302(f) of the Clean Air Act,...

2010-07-01

450

40 CFR 81.16 - Metropolitan Denver Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2010 CFR

...Designation of Air Quality Control Regions § 81.16 Metropolitan Denver Intrastate Air Quality Control Region. The Metropolitan Denver Intrastate Air Quality Control Region (Colorado) consists of...as defined in section 302(f) of the Clean Air Act,...

2009-07-01

451

14 CFR 21.143 - Quality control data requirements; prime manufacturer.  

Code of Federal Regulations, 2010 CFR

...authority of the quality control organization, together with a chart indicating the...relationship of the quality control organization...specifications, and quality control procedures; and (6) A list or chart showing the...

2010-01-01

452

14 CFR 21.143 - Quality control data requirements; prime manufacturer.  

Code of Federal Regulations, 2010 CFR

...authority of the quality control organization, together with a chart indicating the...relationship of the quality control organization...specifications, and quality control procedures; and (6) A list or chart showing the...

2009-01-01

453

42 CFR 84.43 - Quality control records; review by the Institute; revocation of approval.  

Code of Federal Regulations, 2012 CFR

...inspect the applicant's quality control test methods, equipment, and records, and...applicant in regard to quality control test methods, equipment, and records. ...that the applicant's quality control test methods, equipment, or records do...

2012-10-01

454

40 CFR 81.27 - Minneapolis-St. Paul Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2010 CFR

...2009-07-01 false Minneapolis-St. Paul Intrastate Air Quality Control Region...Regions § 81.27 Minneapolis-St. Paul Intrastate Air Quality Control Region. The Minneapolis-St. Paul Intrastate Air Quality Control...

2009-07-01

455

40 CFR 81.27 - Minneapolis-St. Paul Intrastate Air Quality Control Region.  

Code of Federal Regulations, 2010 CFR

...2010-07-01 false Minneapolis-St. Paul Intrastate Air Quality Control Region...Regions § 81.27 Minneapolis-St. Paul Intrastate Air Quality Control Region. The Minneapolis-St. Paul Intrastate Air Quality Control...

2010-07-01

456

Hazards and controls at the Sandia National Laboratories microelectronics development laboratory  

SciTech Connect

The Microelectronics Development Laboratory (MDL) contains 3,000 m{sup 2}, Which includes 1,000 m{sup 2}of Class I clean room space. There are 20 laminar flow Class I clean room bays. The MDL supplies several, full-flow process technologies which produce complementary metal oxide semiconductor (CMOS) integrated circuits using 150 nun diameter silicon wafers. All gases, chemicals and physical hazards used in the fabrication processes are controlled to levels well below regulatory requirements. Facility engineering controls in the MDL include toxic and pyrophoric gas monitoring, interlocks, ventilation, substitution and chemical segregation. Toxic and pyrophoric gases are monitored continuously inside processing tools as well as through the exhaust lines, gas cabinets, the valve boxes, and in general work areas. The toxic gas monitoring systems are interlocked to gas shutoff valves and have both low and high level alarms. In-use process gases are stored in exhausted cabinets. All chemicals and gases are segregated by chemical type. The processes are organized into eight sector areas that consist of photolithography, wet processes, dry etch, ion implant, metals, diffusion, chemical vapor deposition (CVD) and chemical mechanical polishing (CW). Each morning, engineering, safety and facilities personnel meet to review the equipment and wafer lot status and discuss processing issues. Hazards are assessed in the MDL with periodic walkthroughs, continuous toxic and pyrophoric gas monitoring and personal monitoring. All chemicals and gases proposed for use in the MDL are reviewed by the industrial hygienist and must be approved by a manager before they are purchased. All new equipment and processes are reviewed by a hazard and barrier committee and cannot be used in the MDL without the committee`s approval and an IH hazard assessment. Overall risk of operating the MDL has been reduced to a level that is as low as reasonable achievable for this research facility.

Benton, M.A.

1997-03-01

457

Model-Based Control of a Unified Power Quality Conditioner  

Microsoft Academic Search

This paper presents a solution to the control of a unified power quality (PQ) conditioner (UPQC) for PQ improvement in power distribution systems. The problem formulation allows not only harmonic compensation but also voltage sags\\/swells, load demand changes, and power factor correction to be tackled in a unified framework. The proposed controller combines the multivariable regulator theory with H infin

Kian Hoong Kwan; Yun Chung Chu; Ping Lam So

2009-01-01

458

Statistical Process Control: Going to the Limit for Quality.  

ERIC Educational Resources Information Center

Defines the concept of statistical process control, a quality control method used especially in manufacturing. Generally, concept users set specific standard levels that must be met. Makes the point that although employees work directly with the method, management is responsible for its success within the plant. (CH)

Training, 1987

1987-01-01

459

Nonlinear adaptive flight control law design and handling qualities evaluation  

Microsoft Academic Search

This paper considers the design of a stability and control augmentation system for a modern fighter aircraft. The aim of the flight control system is to offer the pilot consistent good flying and handling qualities over a specified flight envelope and to provide robustness to model uncertainties. A nonlinear adaptive backstepping method is proposed to directly deal with the nonlinearities

Lars Sonneveldt; Eduard Richard van Oort; Q. P. Chu; J. A. Mulder

2009-01-01

460

[Analysis of the results of the SEIMC External Quality Control Program. Year 2011].  

PubMed

The External Quality Control Program of the Spanish Society of Infectious Diseases and Clinical Microbiology (Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica [SEIMC]) includes controls for bacteriology, serology, mycology, parasitology, mycobacteria, virology, and molecular microbiology. This article presents the most relevant conclusions and lessons from the 2011 controls. Overall, the results obtained in 2011 confirm the excellent skill and good technical standards found in previous years. Nevertheless, erroneous results can be obtained in any laboratory and in clinically relevant determinations. The results of this program highlight the need to implement both internal and external controls, such as those offered by the SEIMC program, in order to ensure maximal quality of microbiological tests. PMID:23453224

Ruiz de Gopegui Bordes, Enrique; Guna Serrano, M del Remedio; Orta Mira, Nieves; Ovies, María Rosario; Poveda, Marta; Gimeno Cardona, Concepción

2013-02-01

461

Effects of vacuum and controlled atmosphere treatments on insect mortality and lettuce quality.  

PubMed

Laboratory studies were conducted to determine the effects of vacuum and controlled atmosphere on mortality of aphids, Nasonovia ribisnigri (Mosley) and Macrosiphum euphorbiae (Thomas), and leafminer, Liriomyza langei Frick, and on the visual quality