Sample records for laboratory quality control

  1. Laboratory QualityLaboratory Quality ControlControl

    E-print Network

    Laboratory QualityLaboratory Quality ControlControl Nabil A. NIMER Dept . Biotechnology & Genetic thatQA is defined as the overall program that ensures that the final results reported by the laboratory areensures that the final results reported by the laboratory are correct.correct. ""The aim of quality

  2. Analytical laboratory quality control charting

    SciTech Connect

    O'Bryan, Ervin F.

    2001-06-11

    In life the importance of setting goals is stressed. The desired end result must be envisioned to chart a path and determine indicators to provide feedback on the process. Quality does not happen by accident but is achieved through a constant process of setting goals, process development, monitoring process indicators, fine tuning the process, and achieving results. These goals are to be focused and clearly measurable. In industry and life the setting of goals with clear process indicators is often difficult because of the variable end result and scarcity of measurements. Laboratories are fortunate in that they have a plethora of measurements with known or desired end results (controls) to monitor the process and give instantaneous feedback on quality. A key quality tool used by the laboratory to monitor and evaluate the lab processes is control charting. When properly utilized Quality Control (QC) Charts allow labs to be proactive in addressing problems rather than reactive. Several methods are available for control charting and some are listed in the references/information sources. The content for this paper is based on the control-charting program utilized at the Department of Energy's Fernald site. This control-charting program has specific areas of emphasis, simple charts, trend analyses, and effective follow-up.

  3. Quality assurance/quality control manual; National Water Quality Laboratory

    USGS Publications Warehouse

    Pritt, J.W.; Raese, J.W.

    1995-01-01

    Quality-control practices are established for the operation of the U.S. Geological Survey's National Water Quality Laboratory. These practices specify how samples are preserved, shipped, and analyzed in the Laboratory. This manual documents the practices that are currently (1995) used in the Laboratory.

  4. Laboratory Quality Control Based on Risk Management

    PubMed Central

    Nichols, James H.

    2011-01-01

    Risk management is the systematic application of management policies, procedures, and practices to the tasks of analyzing, evaluating, controlling and monitoring risk (the effect of uncertainty on objectives). Clinical laboratories conduct a number of activities that could be considered risk management including verification of performance of new tests, troubleshooting instrument problems and responding to physician complaints. Development of a quality control plan for a laboratory test requires a process map of the testing process with consideration for weak steps in the preanalytic, analytic and postanalytic phases of testing where there is an increased probability of errors. Control processes that either prevent or improve the detection of errors can be implemented at these weak points in the testing process to enhance the overall quality of the test result. This manuscript is based on a presentation at the 2nd International Symposium on Point of Care Testing held at King Faisal Specialist Hospital in Riyadh, Saudi Arabia on October 12-13, 2010. Risk management principles will be reviewed and progress towards adopting a new Clinical and Laboratory Standards Institute Guideline for developing laboratory quality control plans based on risk management will be discussed. PMID:21623049

  5. Quality control in the pulmonary function laboratory.

    PubMed

    Hankinson, J L

    1982-07-01

    The addition of computers to pulmonary function laboratories has reduced quality-control problems. After standards for a test have been selected, the computer can enforce adherence to them. The computer can be programmed to perform periodic calibration checks and other self-diagnostic procedures to ensure that instrumentation and human errors have not gone undetected. The computer can be used to verify that reference values are within acceptable limits and that results for a particular patient are at least internally consistent. The computer greatly reduces the number of measurements and calculations that must be done by hand and therefore improves laboratory efficiency and reduces the probability of human error. Quality-control samples can be processed more frequently with the use of a computer because this task consumes less time than when done by laboratory personnel. Some disadvantages of quality control that have appeared since the introduction of the computer are the potential for undetected failure of computer hardware and software, a risk that has increased with the increase in software complexity, and the potential for the loss of large amounts of information because of its being stored on a single digital medium. To effect quality control in the pulmonary function laboratory one should (1) ensure that procedures and software conform to standards, (2) follow routine calibration-check procedures, (3) check test results for internal consistency and for consistency with other test results, (4) conduct periodic testing of a quality-control subject or reference sample, (5) continually evaluate software performance, (6) carefully evaluate changes in instrumentation and software, and (7) maintain duplicate copies of data on different types of mass storage media. PMID:10315285

  6. HANDBOOK FOR ANALYTICAL QUALITY CONTROL IN RADIOANALYTICAL LABORATORIES

    EPA Science Inventory

    Quality control in the radioanalytical laboratory is discussed. The discussion includes laboratory operating practices, analytical methodology, instrument quality control, and data handling and reporting. Two other sections on handling radioactive materials and counting statistic...

  7. [Our experience with outside laboratory quality control].

    PubMed

    Dochev, D; Arakasheva, V; Nashkov, A; Tsachev, K

    1979-01-01

    The results from the national outside laboratory qualitative control of the clinical diagnostic laboratory investigations for the period September 1975 -- May 1977 were described. The following interlaboratory discrepancy was found on base of a systematic analysis of the data from the last two ring-like check-ups, November 1976 and May 1977, exressed by the variation coefficient (V.C. %); total protein, sodium, potassium and chlorides -- under 10%; cholesterol, urea and total fats -- between 10 and 20%; calcium, phosphorus, iron and creatinine -- over 20%. The highest per cent of admissible results are found with total protein -- to 85%; cholesterol -- to 70.38%; glucosa -- to 73.17%, urea -- to 69.23%, potassium -- to 59.46%, chlorides -- to 57.9%. With sodium, phosphorus, calcium, iron creatinine and uric acid the "admissibility" fluctuates about or under 50 per cent. The values of the qualitative-control indices discussed are comparable with the values obtained from them in the interlaboratory comparisons of other countries. PMID:494628

  8. HANDBOOK FOR ANALYTICAL QUALITY CONTROL IN WATER AND WASTEWATER LABORATORIES

    EPA Science Inventory

    This handbook is addressed to laboratory directors, leaders of field investigations, and other personnel who bear responsibility for water and wastewater data. Subject matter of the handbook is concerned primarily with quality control (QC) for chemical and biological tests and me...

  9. Quality Assurance and Quality Control for Drinking Water Laboratories

    Microsoft Academic Search

    John A. Winter; William L. Budde; Frank Novielli

    1993-01-01

    Soon after the US Environmental Protection Agency (USEPA) was formed in 1972, agency administrators realized that in order to make appropriate decisions for environmental regulation, they must be assured that data being generated by the agency and the 50 states were valid and legally defensible. Thus in 1979, USEPA established a mandatory quality assurance (QA) program for all data generated

  10. Radiation safety and quality control in the cyclotron laboratory.

    PubMed

    Sharma, Sushil; Krause, Gregory; Ebadi, Manuchair

    2006-01-01

    Radiation safety was determined to maintain quality control in the cyclotron laboratory. Based on the results of 438 runs in the Faraday cup (20 microA for 10 min), 20 runs on 18O-water target (40 microA for 2 h) and 10 runs on 18O-gas targets (30 microA for 45 min), we have established that occupationally exposed workers remain 10 +/- 5 times below federal regulatory limits (FRLs) in the cyclotron vault, 30 +/- 8 times below FRL in the radiochemistry laboratory and 200 +/- 10 times below the FRL outside the cyclotron laboratory during beam operation. (The FRL for unrestricted area are <20 microSv in 1 h.) The non-occupationally exposed workers serving in offices in the vicinity of the cyclotron vault within 100 m distance remained 200 times below the FRL irrespective of beam being on or off, suggesting that routine beam operation of 40 microA for 2 h once a day during office hours is safe provided quality control and system performance measures as discussed in this report are strictly maintained. PMID:16497875

  11. 21 CFR 111.110 - What quality control operations are required for laboratory operations associated with the...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...2014-04-01 2014-04-01 false What quality control operations are required for laboratory operations...Process Control System: Requirements for Quality Control § 111.110 What quality control operations are required for laboratory...

  12. Introducing Quality Control in the Chemistry Teaching Laboratory Using Control Charts

    ERIC Educational Resources Information Center

    Schazmann, Benjamin; Regan, Fiona; Ross, Mary; Diamond, Dermot; Paull, Brett

    2009-01-01

    Quality control (QC) measures are less prevalent in teaching laboratories than commercial settings possibly owing to a lack of commercial incentives or teaching resources. This article focuses on the use of QC assessment in the analytical techniques of high performance liquid chromatography (HPLC) and ultraviolet-visible spectroscopy (UV-vis) at…

  13. FIELD AND LABORATORY QUALITY ASSURANCE/QUALITY CONTROL PROTOCOLS AND ACCOMPLISHMENTS FOR THE FERNOW EXPERIMENTAL FOREST WATERSHED ACIDIFICATION STUDY

    EPA Science Inventory

    Field and laboratory quality assurance/quality control (QA/QC) protocols for a whole-watershed acidification study on the Fernow Experimental Forest are described. rocedures are detailed thoroughly to: (1) allow individuals familiar with QA/QC to judge for themselves the quality ...

  14. Metodologia Laboratorial: Controle de Qualidade em Radiologia (Odontologia) Methodology Laboratorial: Control of Quality Control in Radiology (Dentistry)

    Microsoft Academic Search

    Luiz Carlos PARDINI; Plauto Christopher; Aranha WATANABE; Solange Aparecida; Caldeira MONTEIRO

    The authors present pedagogical model of teaching and learning in Radiology (Dentistry) with emphasis on laboratory methodology. The main goal is to train the students to the skills and competencies for Higher Education (Methodology Laboratorial).

  15. Quality in Teaching Laboratories.

    ERIC Educational Resources Information Center

    Stubington, John F.

    1995-01-01

    Describes a Japanese process-oriented approach called KAIZEN for improving the quality of existing teaching laboratories. It provides relevant quality measurements and indicates how quality can be improved. Use of process criteria sidesteps the difficulty of defining quality for laboratory experiments and allows separation of student assessment…

  16. Analytical validation in practice at a quality control laboratory in the Japanese pharmaceutical industry

    Microsoft Academic Search

    S. Seno; S. Ohtake; H. Kohno

    1997-01-01

    Analytical validation is required as the basis for any evaluation activities during manufacturing process validation, cleaning\\u000a validation and validation of the testing method itself in the pharmaceutical industry according to good manufacturing practice\\u000a (GMP) rules and guidelines. Validation of analytical methods and procedures in a quality control (QC) laboratory is implemented\\u000a mainly at the time of transfer or introduction of

  17. [Proposed recommendations for the practical use of internal quality controls (IQC) in a medical biology laboratory].

    PubMed

    Giannoli, Jean-Marc; Szymanowicz, Anton

    2011-01-01

    We propose a set of recommendations and practices to optimize the use of quality control of medical biology examinations. The fundamentals are reviewed: definition of a series of analysis, IQC at one or more level, Westgard alert rules and rejection, practical remedial actions to take for the technician, corrective and preventive actions to be implemented by the biologist. We have also formalized three flowcharts to guide the technician in their daily practice to ensure analytical quality of investigations carried out. These decision trees are the result of the experience submitted by an accredited and professional laboratory attentive to the ongoing improvement of IQC. This article can provide useful assistance to biologists for accreditation but also aims to foster collaboration reliable medical biology laboratory at the appropriate management of patients. PMID:21896419

  18. Bio-Rad Laboratories Q U A L I T Y C O N T R O L Using Quality Control

    E-print Network

    Rodriguez, Carlos

    the attainment of the intended quality of results." "The quality management system shall include decisions. Regular quality control testing to confirm the precision of your test systems is the foremost way is the responsibility of every laboratory. "The laboratory shall design internal quality control systems that verify

  19. Quality Control Guidelines for National Committee for Clinical Laboratory Standards Recommended Broth Macrodilution Testing of Amphotericin B, Fluconazole, and Flucytosine

    Microsoft Academic Search

    M. A. PFALLER; M. BALE; B. BUSCHELMAN; M. LANCASTER; A. ESPINEL-INGROFF; J. H. REX; M. G. RINALDI; C. R. COOPER; R. MCGINNIS

    1995-01-01

    Amphotericin B, fluconazole, and flucytosine (5FC) were tested in a multilaboratory study to establish quality control (QC) guidelines for yeast antifungal susceptibility testing. Ten candidate QC strains were testedinaccordancewithNationalCommitteeforClinicalLaboratoryStandardsM27-Pguidelinesagainstthe three antifungal agents in each of six laboratories. Each laboratory was assigned a unique lot of RPMI 1640 broth medium as well as a lot of RPMI 1640 common to all

  20. QUALITY CONTROLS FOR PCR

    EPA Science Inventory

    The purpose of this presentation is to present an overview of the quality control (QC) sections of a draft EPA document entitled, "Quality Assurance/Quality Control Guidance for Laboratories Performing PCR Analyses on Environmental Samples." This document has been prepared by th...

  1. Evaluation of quality assurance\\/quality control data collected by the US Geological Survey for water-quality activities at the Idaho National Engineering Laboratory, Idaho, 1989 through 1993

    Microsoft Academic Search

    1996-01-01

    Hundreds of water samples were collected by the US Geological Survey (USGS) from 177 monitoring sites for the water quality monitoring program at the Idaho National Engineering Laboratory from 1989 through 1993. Concurrently, replicate pairs of samples and various types of blank samples were collected as part of the quality assurance\\/quality control program. Analyses were performed to determine the concentrations

  2. Application of sigma metrics for the assessment of quality control in clinical chemistry laboratory in Ghana: A pilot study

    PubMed Central

    Afrifa, Justice; Gyekye, Seth A.; Owiredu, William K. B. A.; Ephraim, Richard K. D.; Essien-Baidoo, Samuel; Amoah, Samuel; Simpong, David L.; Arthur, Aaron R.

    2015-01-01

    Background: Sigma metrics provide a uniquely defined scale with which we can assess the performance of a laboratory. The objective of this study was to assess the internal quality control (QC) in the clinical chemistry laboratory of the University of Cape Cost Hospital (UCC) using the six sigma metrics application. Materials and Methods: We used commercial control serum [normal (L1) and pathological (L2)] for validation of quality control. Metabolites (glucose, urea, and creatinine), lipids [triglycerides (TG), total cholesterol, high-density lipoprotein cholesterol (HDL-C)], enzymes [alkaline phosphatase (ALP), alanine aminotransferase (AST)], electrolytes (sodium, potassium, chloride) and total protein were assessed. Between-day imprecision (CVs), inaccuracy (Bias) and sigma values were calculated for each control level. Results: Apart from sodium (2.40%, 3.83%), chloride (2.52% and 2.51%) for both L1 and L2 respectively, and glucose (4.82%), cholesterol (4.86%) for L2, CVs for all other parameters (both L1 and L2) were >5%. Four parameters (HDL-C, urea, creatinine and potassium) achieved sigma levels >1 for both controls. Chloride and sodium achieved sigma levels >1 for L1 but <1 for L2. In contrast, cholesterol, total protein and AST achieved sigma levels <1 for L1 but >1 for L2. Glucose and ALP achieved a sigma level >1 for both control levels whereas TG achieved a sigma level >2 for both control levels. Conclusion: Unsatisfactory sigma levels (<3) where achieved for all parameters using both control levels, this shows instability and low consistency of results. There is the need for detailed assessment of the analytical procedures and the strengthening of the laboratory control systems in order to achieve effective six sigma levels for the laboratory. PMID:25657495

  3. Quality Control Guidelines for National Committee for Clinical Laboratory Standards-Recommended Broth Macrodilution Testing of Ketoconazole and Itraconazole

    Microsoft Academic Search

    JOHN H. REX; MICHAEL A. PFALLER; MICHAEL LANCASTER; FRANK C. ODDS; ANNE BOLMSTROM; ANDMICHAEL G. RINALDI

    1996-01-01

    Ketoconazole and itraconazole were tested in a multilaboratory study to establish quality control (QC) guidelines for yeast antifungal susceptibility testing. Two isolates that had been previously identified as QC isolates for amphotericin B,fluconazole, andflucytosine (Candida parapsilosisATCC 22019 andCandida krusei ATCC 6258) were tested in accordance with the National Committee for Clinical Laboratory Standards M27-P guidelines. Each isolate was tested 20

  4. USGS: National Water Quality Laboratory

    NSDL National Science Digital Library

    The USGS's "National Water Quality Laboratory (NWQL) offers environmental analytical services, including inorganic, organic, and radiochemical constituents, and provides high-quality, reproducible data." Researchers can find a summary of the Laboratory's capabilities, facilities, technology, areas of expertise, and accreditations and certificates. The website offers a Microsoft PowerPoint presentation of its mission. Users can find technical memoranda, a list of NWQL reports and journal articles, and factsheets.

  5. Quality assurance and quality control in light stable isotope laboratories: A case study of Rio Grande, Texas, water samples

    Microsoft Academic Search

    Tyler B. Coplen; Haiping Qi

    2009-01-01

    New isotope laboratories can achieve the goal of reporting the same isotopic composition within analytical uncertainty for the same material analysed decades apart by (1) writing their own acceptance testing procedures and putting them into their mass spectrometric or laser-based isotope-ratio equipment procurement contract, (2) requiring a manufacturer to demonstrate acceptable performance using all sample ports provided with the instrumentation,

  6. Quality assurance and quality control in light stable isotope laboratories: A case study of Rio Grande, Texas, water samples

    USGS Publications Warehouse

    Coplen, T.B.; Qi, H.

    2009-01-01

    New isotope laboratories can achieve the goal of reporting the same isotopic composition within analytical uncertainty for the same material analysed decades apart by (1) writing their own acceptance testing procedures and putting them into their mass spectrometric or laser-based isotope-ratio equipment procurement contract, (2) requiring a manufacturer to demonstrate acceptable performance using all sample ports provided with the instrumentation, (3) for each medium to be analysed, prepare two local reference materials substantially different in isotopic composition to encompass the range in isotopic composition expected in the laboratory and calibrated them with isotopic reference materials available from the International Atomic Energy Agency (IAEA) or the US National Institute of Standards and Technology (NIST), (4) using the optimum storage containers (for water samples, sealing in glass ampoules that are sterilised after sealing is satisfactory), (5) interspersing among sample unknowns local laboratory isotopic reference materials daily (internationally distributed isotopic reference materials can be ordered at three-year intervals, and can be used for elemental analyser analyses and other analyses that consume less than 1 mg of material) - this process applies to H, C, N, O, and S isotope ratios, (6) calculating isotopic compositions of unknowns by normalising isotopic data to that of local reference materials, which have been calibrated to internationally distributed isotopic reference materials, (7) reporting results on scales normalised to internationally distributed isotopic reference materials (where they are available) and providing to sample submitters the isotopic compositions of internationally distributed isotopic reference materials of the same substance had they been analysed with unknowns, (8) providing an audit trail in the laboratory for analytical results - this trail commonly will be in electronic format and might include a laboratory information management system, (9) making at regular intervals a complete backup of laboratory analytical data (both of samples logged into the laboratory and of mass spectrometric analyses), being sure to store one copy of this backup offsite, and (10) participating in interlaboratory comparison exercises sponsored by the IAEA and other agencies at regular intervals. ?? Taylor & Francis.

  7. Statistical Methods for Establishing Quality Control Ranges for Antibacterial Agents in Clinical and Laboratory Standards Institute Susceptibility Testing?

    PubMed Central

    Turnidge, John; Bordash, Gerry

    2007-01-01

    Quality control (QC) ranges for antimicrobial agents against QC strains for both dilution and disk diffusion testing are currently set by the Clinical and Laboratory Standards Institute (CLSI), using data gathered in predefined structured multilaboratory studies, so-called tier 2 studies. The ranges are finally selected by the relevant CLSI subcommittee, based largely on visual inspection and a few simple rules. We have developed statistical methods for analyzing the data from tier 2 studies and applied them to QC strain-antimicrobial agent combinations from 178 dilution testing data sets and 48 disk diffusion data sets, including a method for identifying possible outlier data from individual laboratories. The methods are based on the fact that dilution testing MIC data were log normally distributed and disk diffusion zone diameter data were normally distributed. For dilution testing, compared to QC ranges actually set by CLSI, calculated ranges were identical in 68% of cases, narrower in 7% of cases, and wider in 14% of cases. For disk diffusion testing, calculated ranges were identical to CLSI ranges in 33% of cases, narrower in 8% of cases, and 1 to 2 mm wider in 58% of cases. Possible outliers were detected in 8% of diffusion test data but none of the disk diffusion data. Application of statistical techniques to the analysis of QC tier 2 data and the setting of QC ranges is relatively simple to perform on spreadsheets, and the output enhances the current CLSI methods for setting of QC ranges. PMID:17438045

  8. Importance/performance analysis: a tool for service quality control by clinical laboratories.

    PubMed

    Scammon, D L; Weiss, R

    1991-01-01

    A study of customer satisfaction with clinical laboratory service is used as the basis for identifying potential improvements in service and more effectively targeting marketing activities to enhance customer satisfaction. Data on customer satisfaction are used to determine the aspects of service most critical to customers, how well the organization is doing in delivery of service, and how consistent service delivery is. Importance-performance analysis is used to highlight areas for future resource reallocation and strategic emphasis. Suggestions include the establishment of performance guidelines for customer contact personnel, the enhancement of timely delivery of reports via electronic transmission (computer and fax), and the development of standardized graphics for request and report forms to facilitate identification of appropriate request forms and guide clients to key items of information on reports. PMID:10110443

  9. Reliability of nucleic acid amplification methods for detection of Chlamydia trachomatis in urine: results of the first international collaborative quality control study among 96 laboratories

    Microsoft Academic Search

    Roel P. Verkooyen; Gerda T. Noordhoek; Paul E. Klapper; Jim Reid; Jurjen Schirm; Graham M. Cleator; Margareta Ieven; Gunnar Hoddevik

    2003-01-01

    The first European Quality Control Concerted Action study was organized to\\u000a assess the ability of laboratories to detect Chlamydia trachomatis in a\\u000a panel of urine samples by nucleic acid amplification tests (NATs). The\\u000a panel consisted of lyophilized urine samples, including three negative,\\u000a two strongly positive, and five weakly positive samples. Ninety-six\\u000a laboratories in 22 countries participated with a total of

  10. Laboratory 10 Control Systems Laboratory ECE3557 Laboratory 10

    E-print Network

    Laboratory 10 Control Systems Laboratory ECE3557 Laboratory 10 State Feedback Controller for Position Control of a DC Servo 10.1 Objective The objective of this laboratory is to position the gears, we will use the state space model of the DC servo introduced in the laboratory 3 (refer to [1

  11. Reliability of Nucleic Acid Amplification Methods for Detection of Chlamydia trachomatis in Urine: Results of the First International Collaborative Quality Control Study among 96 Laboratories

    Microsoft Academic Search

    Roel P. Verkooyen; Gerda T. Noordhoek; Paul E. Klapper; Jim Reid; Jurjen Schirm

    The first European Quality Control Concerted Action study was organized to assess the ability of labora- tories to detect Chlamydia trachomatis in a panel of urine samples by nucleic acid amplification tests (NATs). The panel consisted of lyophilized urine samples, including three negative, two strongly positive, and five weakly positive samples. Ninety-six laboratories in 22 countries participated with a total

  12. Quality Control Introduction

    E-print Network

    Vickers, James

    Quality Control 46.2 Introduction Quality control via the use of statistical methods is a very successful at applying statistical methods to industrial quality control and have gained a significant become. It is because of the global nature of modern industrial competition that quality control, or more

  13. Control of jet fuel quality

    Microsoft Academic Search

    V. M. Gomozov; G. R. Stanina

    1968-01-01

    The proposed method of control of jet fuel quality permits:1)An increase in the controllability of the process of preliminary distillation by reducing the time of fuel analysis from 70–90 to 20–25 min; at the same time the expense of the laboratory control of fuel is reduced;2)the elimination of the need for installing a large number of automatic on-stream quality analyzers;3)a

  14. Laboratory Policy Methods of Analysis & Quality Assurance

    E-print Network

    Maxwell, Bruce D.

    Laboratory Policy Methods of Analysis & Quality Assurance The Cereal Quality Lab (CQL) uses quality data. The laboratory participates in collaborative studies organized by AACC, Wheat Quality by the laboratory is treated confidentially and will not be revealed to third parties without prior consent

  15. Quality Assurance Program for Molecular Medicine Laboratories

    PubMed Central

    Hajia, M; Safadel, N; Samiee, S Mirab; Dahim, P; Anjarani, S; Nafisi, N; Sohrabi, A; Rafiee, M; Sabzavi, F; Entekhabi, B

    2013-01-01

    Background: Molecular diagnostic methods have played and continuing to have a critical role in clinical laboratories in recent years. Therefore, standardization is an evolutionary process that needs to be upgrade with increasing scientific knowledge, improvement of the instruments and techniques. The aim of this study was to design a quality assurance program in order to have similar conditions for all medical laboratories engaging with molecular tests. Methods: We had to design a plan for all four elements; required space conditions, equipments, training, and basic guidelines. Necessary guidelines was prepared and confirmed by the launched specific committee at the Health Reference Laboratory. Results: Several workshops were also held for medical laboratories directors and staffs, quality control manager of molecular companies, directors and nominees from universities. Accreditation of equipments and molecular material was followed parallel with rest of program. Now we are going to accredit medical laboratories and to evaluate the success of the program. Conclusion: Accreditation of medical laboratory will be succeeding if its basic elements are provided in advance. Professional practice guidelines, holding training and performing accreditation the molecular materials and equipments ensured us that laboratories are aware of best practices, proper interpretation, limitations of techniques, and technical issues. Now, active external auditing can improve the applied laboratory conditions toward the defined standard level. PMID:23865028

  16. Quality and safety aspects in histopathology laboratory.

    PubMed

    Adyanthaya, Soniya; Jose, Maji

    2013-09-01

    Histopathology is an art of analyzing and interpreting the shapes, sizes and architectural patterns of cells and tissues within a given specific clinical background and a science by which the image is placed in the context of knowledge of pathobiology, to arrive at an accurate diagnosis. To function effectively and safely, all the procedures and activities of histopathology laboratory should be evaluated and monitored accurately. In histopathology laboratory, the concept of quality control is applicable to pre-analytical, analytical and post-analytical activities. Ensuring safety of working personnel as well as environment is also highly important. Safety issues that may come up in a histopathology lab are primarily those related to potentially hazardous chemicals, biohazardous materials, accidents linked to the equipment and instrumentation employed and general risks from electrical and fire hazards. This article discusses quality management system which can ensure quality performance in histopathology laboratory. The hazards in pathology laboratories and practical safety measures aimed at controlling the dangers are also discussed with the objective of promoting safety consciousness and the practice of laboratory safety. PMID:24574660

  17. Quality and safety aspects in histopathology laboratory

    PubMed Central

    Adyanthaya, Soniya; Jose, Maji

    2013-01-01

    Histopathology is an art of analyzing and interpreting the shapes, sizes and architectural patterns of cells and tissues within a given specific clinical background and a science by which the image is placed in the context of knowledge of pathobiology, to arrive at an accurate diagnosis. To function effectively and safely, all the procedures and activities of histopathology laboratory should be evaluated and monitored accurately. In histopathology laboratory, the concept of quality control is applicable to pre-analytical, analytical and post-analytical activities. Ensuring safety of working personnel as well as environment is also highly important. Safety issues that may come up in a histopathology lab are primarily those related to potentially hazardous chemicals, biohazardous materials, accidents linked to the equipment and instrumentation employed and general risks from electrical and fire hazards. This article discusses quality management system which can ensure quality performance in histopathology laboratory. The hazards in pathology laboratories and practical safety measures aimed at controlling the dangers are also discussed with the objective of promoting safety consciousness and the practice of laboratory safety. PMID:24574660

  18. The Andrology Laboratory in an Assisted Reproductive Technologies Program Quality Assurance and Laboratory Methodology

    Microsoft Academic Search

    CHARLES H. MULLER

    Assuring the highest possible quality of care to the patient is the first goal of the andrology laboratory. Quality con- trol and quality assurance as they apply to the andrology labo- ratory are outlined, and special problems in quality control for sperm function assays are addressed. An example of the patient review process is presented. Quality of care also depends

  19. Quality Control Microbiologist

    NSDL National Science Digital Library

    This video, presented by WGBH, takes a look at a day in the life of a quality control microbiologist at a pharmaceutical company and provides a detailed account of what is possible with a microbiology degree, including the hands-on laboratory aspects field. This video would be helpful for anyone interested in a degree in microbiology, as well as anyone that is currently earning a degree in this field but is still unsure about what to do with it. Educators will also find a background essay, discussion questions, and standards alignment for the material. Running time for the video is 2:38.

  20. 222-S laboratory quality assurance plan

    SciTech Connect

    Meznarich, H.K.

    1995-04-01

    This document provides quality assurance guidelines and quality control requirements for analytical services. This document is designed on the basis of Hanford Analytical Services Quality Assurance Plan (HASQAP) technical guidelines and is used for governing 222-S and 222-SA analytical and quality control activities. The 222-S Laboratory provides analytical services to various clients including, but not limited to, waste characterization for the Tank Waste Remediation Systems (TWRS), waste characterization for regulatory waste treatment, storage, and disposal (TSD), regulatory compliance samples, radiation screening, process samples, and TPA samples. A graded approach is applied on the level of sample custody, QC, data verification, and data reporting to meet the specific needs of the client.

  1. [Total quality management in laboratory medicine].

    PubMed

    Vogt, W

    1998-12-01

    The German Public Health will be continuously challenged in the future. It has to be assumed that modified managed care will not only take place sporadically. Thus, quality aspects of services gain more and more significance. Only suppliers will be successful who can offer services of highest quality at lowest prices. Quality in a comprehensive sense has to be substantiated in the near future. It is recommended to apply industry proven models also in public health service. Medical laboratories can be pioneers in this field as they have been already in the past. All previously proposed procedures can not describe quality of results comprehensively. They are based to a high degree on external control. Total quality management, however, represents a comprehensive approach. Principles are zero-defect approach, customer orientation and system management. Quality is given in the sense of TQM if the customer is permanently satisfied with the service of the supplier. In such a way, the customer defines quality of service. A customer is everyone who receives products or services. TQM overcomes the drawbacks of quality management systems, which are strongly formal and oriented by external control, as accreditation (EN 45,000) or certification (ISO 9000). Competition between hospitals is a declared goal of German health politics because usually quality is increased and cost decreased as a consequence. Competition means also comparison of services. TQM emphasizes benchmarking especially among the best suppliers. PMID:10028601

  2. Evaluation of quality assurance/quality control data collected by the U.S. Geological Survey for water-quality activities at the Idaho National Engineering and Environmental Laboratory, Idaho, 1994 through 1995

    SciTech Connect

    Williams, L.M.

    1997-03-01

    More than 4,000 water samples were collected by the US Geological Survey (USGS) from 179 monitoring sites for the water-quality monitoring program at the Idaho National Engineering Laboratory from 1994 through 1995. Approximately 500 of the water samples were replicate or blank samples collected for the quality assurance/quality control program. Analyses were performed to determine the concentrations of major ions, nutrients, trace elements, gross radioactivity and radionuclides, total organic carbon, and volatile organic compounds in the samples. To evaluate the precision of field and laboratory methods, analytical results of the replicate pairs of samples were compared statistically for equivalence on the basis of the precision associated with each result. In all, the statistical comparison of the data indicated that 95% of the replicate pairs were equivalent. Within the major ion analyses, 97% were equivalent; nutrients, 88%; trace elements, 95%; gross radioactivity and radionuclides, 93%; and organic constituents, 98%. Ninety percent or more of the analytical results for each constituent were equivalent, except for nitrite, orthophosphate, phosphorus, aluminum, iron, strontium-90, and total organic carbon.

  3. Use of prior manufacturer specifications with Bayesian logic eludes preliminary phase issues in quality control: an example in a hemostasis laboratory.

    PubMed

    Tsiamyrtzis, Panagiotis; Sobas, Frédéric; Négrier, Claude

    2015-07-01

    The present study seeks to demonstrate the feasibility of avoiding the preliminary phase, which is mandatory in all conventional approaches for internal quality control (IQC) management. Apart from savings on the resources consumed by the preliminary phase, the alternative approach described here is able to detect any analytic problems during the startup and provide a foundation for subsequent conventional assessment. A new dynamically updated predictive control chart (PCC) is used. Being Bayesian in concept, it utilizes available prior information. The manufacturer's prior quality control target value, the manufacturer's maximum acceptable interassay coefficient of variation value and the interassay standard deviation value defined during method validation in each laboratory, allow online IQC management. An Excel template, downloadable from journal website, allows easy implementation of this alternative approach in any laboratory. In the practical case of prothrombin percentage measurement, PCC gave no false alarms with respect to the 1ks rule (with same 5% false-alarm probability on a single control sample) during an overlap phase between two IQC batches. Moreover, PCCs were as effective as the 1ks rule in detecting increases in both random and systematic error after the minimal preliminary phase required by medical biology guidelines. PCCs can improve efficiency in medical biology laboratories. PMID:25978121

  4. Bio-Rad Laboratories Q u a l i t y C O n t r O l s f O r P h y s i C i a n O f f i C e l a b O r at O r i e s Quality Controls for Physician Office

    E-print Network

    Rodriguez, Carlos

    at O r i e s Quality Controls for Physician Office Laboratories Enjoy the benefits of Bio-Rad's Quality System. Implementing the use of independent quality controls on a daily basis in your laboratory. Troubleshoot and Resolve Issue REPORT Reliable Patient Results START Run Quality Control Is Control Value

  5. Laboratory quality improvement in Thailand's northernmost provinces

    Microsoft Academic Search

    S. Kanitvittaya; U. Suksai; O. Suksripanich; V. Pobkeeree

    2010-01-01

    Purpose – In Thailand nearly 1,000 public health laboratories serve 65 million people. A qualified indicator of a good quality laboratory is Thailand Medical Technology Council certification. Consequently, Chiang Rai Regional Medical Sciences Center established a development program for laboratory certification for 29 laboratories in the province. This paper seeks to examine this issue. Design\\/methodology\\/approach – The goal was to

  6. Quality Control in Evaluation.

    ERIC Educational Resources Information Center

    Trochim, William M. K.; Visco, Ronald J.

    1985-01-01

    Quality control in the auditing profession has developed useful practices that are applied to the research and evaluation process. By identifying and controlling sources of bias and noise in the system of inquiry, the quality of evaluative evidence can be enhanced for both present and future use. (Author/BS)

  7. 1990 National Water Quality Laboratory Services Catalog

    USGS Publications Warehouse

    Pritt, Jeffrey, (Edited By); Jones, Berwyn E.

    1989-01-01

    PREFACE This catalog provides information about analytical services available from the National Water Quality Laboratory (NWQL) to support programs of the Water Resources Division of the U.S. Geological Survey. To assist personnel in the selection of analytical services, the catalog lists cost, sample volume, applicable concentration range, detection level, precision of analysis, and preservation techniques for samples to be submitted for analysis. Prices for services reflect operationa1 costs, the complexity of each analytical procedure, and the costs to ensure analytical quality control. The catalog consists of five parts. Part 1 is a glossary of terminology; Part 2 lists the bottles, containers, solutions, and other materials that are available through the NWQL; Part 3 describes the field processing of samples to be submitted for analysis; Part 4 describes analytical services that are available; and Part 5 contains indices of analytical methodology and Chemical Abstract Services (CAS) numbers. Nomenclature used in the catalog is consistent with WATSTORE and STORET. The user is provided with laboratory codes and schedules that consist of groupings of parameters which are measured together in the NWQL. In cases where more than one analytical range is offered for a single element or compound, different laboratory codes are given. Book 5 of the series 'Techniques of Water Resources Investigations of the U.S. Geological Survey' should be consulted for more information about the analytical procedures included in the tabulations. This catalog supersedes U.S. Geological Survey Open-File Report 86-232 '1986-87-88 National Water Quality Laboratory Services Catalog', October 1985.

  8. Laboratory 11 Control Systems Laboratory ECE3557 Laboratory 11

    E-print Network

    in this laboratory is illustrated. For this laboratory, the servo is used in the high gear ratio configuration (refer state feedback controller for endpoint position control in the face of flexibility effects for a flexible joint mounted on the SRV-02DC servomotor. For this, we will use the state space model

  9. Inclusion of quality controls on leishmaniases molecular tests to increase diagnostic accuracy in research and reference laboratories.

    PubMed

    da C Gonçalves-de-Albuquerque, Suênia; Pessoa-e-Silva, Rômulo; Trajano-Silva, Lays A M; de Morais, Rayana C S; Brandão-Filho, Sinval P; de Paiva-Cavalcanti, Milena

    2015-04-01

    Early detection of leishmaniases and prompt institution of treatment are paramount for individuals and communities affected by these diseases. To overcome the remaining limitations inherent to molecular methods currently used and to ensure the accuracy of results in leishmaniases diagnosis, two triplex polymerase chain reaction (PCR) assays with quality controls for the reactions were developed. Validity indicators were assessed in 186 dog blood samples from endemic areas in Brazil. The level of agreement between the new tools and their singleplex protocols was assessed by kappa analysis. The triplex PCR for visceral leishmaniasis showed sensitivity (S) = 78.68 %, specificity (E) = 85.29 %, and efficiency (e) = 81.05 %. The cutaneous leishmaniasis protocol showed S = 97.29 %, E = 79.16 %, and e = 90.16 %. Both protocols showed good agreement with gold standards. These new tools enable, in a single reaction, the diagnosis of the diseases and the evaluation of the sample quality and DNA extraction process, thus reducing the cost of reagents and avoiding the eventual need for collecting a second sample. PMID:25428552

  10. QUALITY CONTROL - VARIABILITY IN PROTOCOLS

    EPA Science Inventory

    The EPA Risk Reduction Engineering Laboratory?s Quality Assurance Office, which published the popular pocket guide Preparing Perfect Project Plans, is now introducing another quality assurance reference aid. The document Variability in Protocols (VIP) was initially designed as a ...

  11. Methods of analysis by the U.S. Geological Survey National Water Quality Laboratory; processing, taxonomy, and quality control of benthic macroinvertebrate samples

    USGS Publications Warehouse

    Moulton, Stephen R., II; Carter, James L.; Grotheer, Scott A.; Cuffney, Thomas F.; Short, Terry M.

    2000-01-01

    Qualitative and quantitative methods to process benthic macroinvertebrate (BMI) samples have been developed and tested by the U.S. Geological Survey?s National Water Quality Laboratory Biological Group. The qualitative processing method is based on visually sorting a sample for up to 2 hours. Sorting focuses on attaining organisms that are likely to result in taxonomic identifications to lower taxonomic levels (for example, Genus or Species). Immature and damaged organisms are also sorted when they are likely to result in unique determinations. The sorted sample remnant is scanned briefly by a second person to determine if obvious taxa were missed. The quantitative processing method is based on a fixed-count approach that targets some minimum count, such as 100 or 300 organisms. Organisms are sorted from randomly selected 5.1- by 5.1-centimeter parts of a gridded subsampling frame. The sorted remnant from each sample is resorted by a second individual for at least 10 percent of the original sort time. A large-rare organism search is performed on the unsorted remnant to sort BMI taxa that were not likely represented in the sorted grids. After either qualitatively or quantitatively sorting the sample, BMIs are identified by using one of three different types of taxonomic assessment. The Standard Taxonomic Assessment is comparable to the U.S. Environmental Protection Agency Rapid Bioassessment Protocol III and typically provides Genus- or Species-level taxonomic resolution. The Rapid Taxonomic Assessment is comparable to the U.S. Environmental Protection Agency Rapid Bioassessment Protocol II and provides Familylevel and higher taxonomic resolution. The Custom Taxonomic Assessment provides Species-level resolution whenever possible for groups identified to higher taxonomic levels by using the Standard Taxonomic Assessment. The consistent use of standardized designations and notes facilitates the interpretation of BMI data within and among water-quality studies. Taxonomic identifications are quality assured by verifying all referenced taxa and randomly reviewing 10 percent of the taxonomic identifications performed weekly by Biological Group taxonomists. Taxonomic errors discovered during this review are corrected. BMI data are reviewed for accuracy and completeness prior to release. BMI data are released phylogenetically in spreadsheet format and unprocessed abundances are corrected for laboratory and field subsampling when necessary.

  12. Evaluation of Quality-Assurance/Quality-Control Data Collected by the U.S. Geological Survey from Wells and Springs between the Southern Boundary of the Idaho National Engineering and Environmental Laboratory and the Hagerman Area, Idaho, 1989 through 1995

    SciTech Connect

    Williams, L.M.; Bartholomay, R.C.; Campbell, L.J.

    1998-10-01

    The U.S. Geological (USGS) and the Idaho Department of Water Resources, in cooperation with the U.S. Department of Energy, collected and analyzed water samples to monitor the water quality of the Snake River Plain aquifer from the southern boundary of the Idaho National Engineering and Environmental Laboratory to the Hagerman area, Idaho. Concurrently, replicate samples and blank samples were collected and analyzed as part of the quality-assurance/quality-control program. Samples were analyzed from inorganic constituents, gross radioactivity and radionuclides, organic constituents, and stable isotopes. To evaluate the precision of field and laboratory methods, analytical results of the water-quality and replicate samples were compared statistically for equivalence on the basis of the precision associated with each result. Statistical comparisons of the data indicated that 95 percent of the results of the replicate pairs were equivalent. Blank-sample analytical results indicated th at the inorganic blank water and volatile organic compound blank water from the USGS National Water Quality Laboratory and the distilled water from the Idaho Department of Water Resources were suitable for blanks; blank water from other sources was not. Equipment-blank analytical results were evaluated to determine if a bias had been introduced and possible sources of bias. Most equipment blanks were analyzed for trace elements and volatile organic compounds; chloroform was found in one equipment blank. Two of the equipment blanks were prepared after collection and analyses of the water-quality samples to determine whether contamination had been introduced during the sampling process. Results of one blank indicated that a hose used to divert water away from pumps and electrical equipment had contaminated the samples with some volatile organic compounds. Results of the other equipment blank, from the apparatus used to filter dissolved organic carbon samples, indicated that the filtering apparatus did not affect water-quality samples.

  13. 21 CFR 606.140 - Laboratory controls.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 2014-04-01 2014-04-01 false Laboratory controls. 606.140 Section 606.140...MANUFACTURING PRACTICE FOR BLOOD AND BLOOD COMPONENTS Laboratory Controls § 606.140 Laboratory controls. Laboratory control...

  14. 21 CFR 606.140 - Laboratory controls.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 2012-04-01 2012-04-01 false Laboratory controls. 606.140 Section 606.140...MANUFACTURING PRACTICE FOR BLOOD AND BLOOD COMPONENTS Laboratory Controls § 606.140 Laboratory controls. Laboratory control...

  15. 21 CFR 606.140 - Laboratory controls.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 2013-04-01 2013-04-01 false Laboratory controls. 606.140 Section 606.140...MANUFACTURING PRACTICE FOR BLOOD AND BLOOD COMPONENTS Laboratory Controls § 606.140 Laboratory controls. Laboratory control...

  16. 21 CFR 606.140 - Laboratory controls.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 2010-04-01 2010-04-01 false Laboratory controls. 606.140 Section 606.140...MANUFACTURING PRACTICE FOR BLOOD AND BLOOD COMPONENTS Laboratory Controls § 606.140 Laboratory controls. Laboratory control...

  17. 21 CFR 606.140 - Laboratory controls.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 2011-04-01 2010-04-01 true Laboratory controls. 606.140 Section 606.140...MANUFACTURING PRACTICE FOR BLOOD AND BLOOD COMPONENTS Laboratory Controls § 606.140 Laboratory controls. Laboratory control...

  18. Quality Control of Pharmaceuticals

    PubMed Central

    Levi, Leo; Walker, George C.; Pugsley, L. I.

    1964-01-01

    Quality control is an essential operation of the pharmaceutical industry. Drugs must be marketed as safe and therapeutically active formulations whose performance is consistent and predictable. New and better medicinal agents are being produced at an accelerated rate. At the same time more exacting and sophisticated analytical methods are being developed for their evaluation. Requirements governing the quality control of pharmaceuticals in accordance with the Canadian Food and Drugs Act are cited and discussed. PMID:14199105

  19. Multivariate quality control

    Microsoft Academic Search

    J. Edward Jackson

    1985-01-01

    This paper includes both the motivation for multivariate quality control, and a discussion of some ot rhe techniques currently available. The emphasis focuses primarily on control charts and includes the T -chart, the use of principal components anm some recent developments, multivariate analogs of CUSUM cnarts and the use of the Andrews procedure. Some of the problems associated with multivariate

  20. Quality control tests of lab-reared Cydia pomonella and Cactoblastis cactorum field performance: Comparison of laboratory and field bioassays.

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Research, operational, and commercial programs which rely on mass-reared insects of high quality and performance, need accurate methods for monitoring quality degradation during each step of production, handling and release. With continued interest in the use of the sterile insect technique (SIT) a...

  1. Environmental quality control report. [Semiannual] report, July--December 1988

    SciTech Connect

    Bishop, C.T.

    1989-04-14

    This report presents the details of the Mound Laboratory EPA-NPDES Quality Assurance Program, the DOE Quality Assessment Program Results, Proficiency Environmental Testing Program and Plutonium in Urine Quality Control for 1988.

  2. Emerging concepts of quality assurance in clinical laboratories.

    PubMed

    Naz, Sumera; Saddar-ud-din, Agha

    2006-09-01

    Quality Assurance is a management system designed to achieve an acceptable level of quality services, prevent poor quality and in laboratories is intended to ensure reliability of results. It comprehensively includes controlling the quality of procedures at each and every step including Pre-analytical (specimen collection and transport), Analytical (specimen processing in the lab) and Post-analytical (reporting and interpretation of results). Concept of total quality management (TQM) is closely interlinked with good laboratory practices and goes far beyond the widely practiced conventional Quality Control (QC) procedures. TQM includes Technical accuracy and precision, equipment and supplies, staff training and skill, financial management (cost effectiveness), lab safety, communication etc. Recent pressures on pathology laboratories have meant that laboratories no longer have the numbers of scientists and pathologists they had in the past. This has resulted in more questions being asked of the QA staff with a steady increase in the number of scientists employed to address this demand. Quality improvement in the modern clinical laboratory environment entails the continuous inspection and refinement of processes to ensure the efficient delivery of services that meet the needs and expectations of those who use them. PMID:17091755

  3. The andrology laboratory in an Assisted Reproductive Technologies program. Quality assurance and laboratory methodology.

    PubMed

    Muller, C H

    1992-01-01

    Assuring the highest possible quality of care to the patient is the first goal of the andrology laboratory. Quality control and quality assurance as they apply to the andrology laboratory are outlined, and special problems in quality control for sperm function assays are addressed. An example of the patient review process is presented. Quality of care also depends on the ability of the laboratory to perform appropriate tests of sperm function that can diagnose sperm defects, predict success or failure of in vitro fertilization, and lead to rational therapies for sperm dysfunctions. Methods for, and diagnostic value of, sperm swim-out, enhanced sperm penetration assays, acrosome reaction assessment, motility analysis of capacitating sperm, and sperm-zona binding assays are reviewed. No single test, other than in vitro fertilization itself, is capable of providing a complete diagnosis or a highly accurate prediction. A battery of sperm function tests, arranged in an algorithm, is presented as a theoretically better approach. PMID:1429216

  4. USGS Laboratory Review Program Ensures Analytical Quality

    USGS Publications Warehouse

    Erdmann, David E.

    1995-01-01

    The USGS operates a review program for laboratories that analyze samples for USGS environmental investigations. This program has been effective in providing QA feedback to laboratories while ensuring that analytical data are consistent, of satisfactory quality, and meet the data objectives of the investigation.

  5. Information systems as a quality management tool in clinical laboratories

    NASA Astrophysics Data System (ADS)

    Schmitz, Vanessa; Rosecler Bez el Boukhari, Marta

    2007-11-01

    This article describes information systems as a quality management tool in clinical laboratories. The quality of laboratory analyses is of fundamental importance for health professionals in aiding appropriate diagnosis and treatment. Information systems allow the automation of internal quality management processes, using standard sample tests, Levey-Jennings charts and Westgard multirule analysis. This simplifies evaluation and interpretation of quality tests and reduces the possibility of human error. This study proposes the development of an information system with appropriate functions and costs for the automation of internal quality control in small and medium-sized clinical laboratories. To this end, it evaluates the functions and usability of two commercial software products designed for this purpose, identifying the positive features of each, so that these can be taken into account during the development of the proposed system.

  6. Automatic Control Laboratory ETH, Zurich

    E-print Network

    Lygeros, John

    Automatic Control Laboratory ETH, Z¨urich Physikstrasse 3 8092 Z¨urich, Switzerland +41 44 632 22 71 How to get to the Automatic Control Laboratory (IfA) From the Z¨urich airport: · By Taxi. Taxi of the Airport Center. There are also ticket machines close to the elevators down to the platforms. A button

  7. Preparation and certification of a reference material on PCBs in pig fat and its application in quality control in monitoring laboratories during the Belgian "PCB-crisis".

    PubMed

    Bester, K; de Vos, P; Le Guern, L; Harbeck, S; Hendrickx, F; Kramer, G N; Linsinger, T; Mertens, I; Schimmel, H; Sejerøe-Olsen, B; Pauwels, J; De Poorter, G; Rimkus, G G; Schlabach, M

    2001-08-01

    In this article, the production and validation of a new certified reference material "PCBs in animal fat" for the control of the maximum level of 200 ng/g setup by the European Communities for veterinary products from Belgium is described. Three materials are established: a blank, one material with about 100 ng/g and one with about 200 ng/g (sum of seven PCBs). Data on the production and certification are given. Additionally, this material was used as an unknown test material in the quality assurance program of the Belgium meat monitoring system (before the certification of the material). While the certification was performed with an uncertainty of less than 10%, the round robin exhibited larger deviations. However, these deviations were less than 20% for most of the 30 participating laboratories. Only two had significantly higher deviations. PMID:11482639

  8. Implementation of a quality management system in public health laboratories in the Republic of Georgia

    Microsoft Academic Search

    Brandy Greenhill

    2012-01-01

    Through a cooperative agreement with the Centers for Disease Control and Prevention (CDC), the Clinical and Laboratory Standards Institute and CDC Laboratory Strengthening Department implemented quality management systems (QMS) into the two national public health laboratories in Tbilisi, Georgia. The QMS was based on CLSI's document Quality Management System: A Model for Laboratory Services; Approved Guideline and ISO 15189, Medical

  9. Total quality management in clinical virology laboratories.

    PubMed

    Tibbets, M W; Gomez, R; Kannangai, R; Sridharan, G

    2006-10-01

    The diagnostic laboratories in India are progressively promoting higher standards and are moving towards accreditation and international acceptance. Hence, the concept of "Quality" will need to be understood and implemented. Total quality management (TQM) in a laboratory is an integrated program involving all laboratory staff and management. TQM is a framework to operate and it is aiming for integration, consistency, increase in efficiency and a continuous drive for improvement. A well structured clinical virology service will include serology setup, cell culture facility and capacity for molecular diagnosis. The quality of results from the laboratory is significantly influenced by many pre-analytical and post-analytical factors which needed attention. The end goal of the TQM should be to provide the best care possible for the patient. PMID:17185843

  10. Control Systems Engineering Laboratory Daniel E. Rivera

    E-print Network

    Langerhans, Brian

    Control Systems Engineering Laboratory CSEL Daniel E. Rivera Control Systems Engineering Laboratory Behavioral Interventions 1 #12;Control Systems Engineering Laboratory CSEL Presentation Outline · What are adaptive behavioral interventions? · (Brief) overview of control systems engineering, · Analysis and design

  11. [Quality control of essential oil of muscat sage (Salvia sclarea) during laboratory and industrial preparation. IV. Causes of color changes].

    PubMed

    Thet, M; Petri, G

    1990-11-01

    Essential oils of muscat sage--of various habitats in different developmental stages as well as the essential oils prepared with half industrial and laboratorial procedures--have been studied. It has been found that compositions of essential oils do not differ significantly, the difference is only in such an extent that could be expected on the ground of environmental and ontogenetic effects. On the basis of tests it has been established that formation of brown oil is in connection with content of copper of apparatus (boiler, tube); Therefore applications of vessel and connections containing copper or copper impurities must be avoided in preparation of the clear essential oil. PMID:2087987

  12. Quality Control Mini Culture Project

    E-print Network

    Vardeman, Stephen B.

    IE 361 Quality Control Mini Culture Project "ROBUST ENGINEERING" For: Dr. Vardeman By: Jason as the products quality get farther away from the target value. The traditional control limits were defined main types of quality in a product. These types are (1) customer quality and (2) engineered quality

  13. 21 CFR 111.110 - What quality control operations are required for laboratory operations associated with the...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    21 Food and Drugs 2 2010-04-01...associated with the production and process control...Section 111.110 Food and Drugs FOOD...SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION...DIETARY SUPPLEMENTS Production and Process...

  14. National Water Quality Laboratory, 1995 services catalog

    USGS Publications Warehouse

    Timme, P.J.

    1995-01-01

    This Services Catalog contains information about field supplies and analytical services available from the National Water Quality Laboratory in Denver, Colo., and field supplies available from the Quality Water Service Unit in Ocala, Fla., to members of the U.S. Geological Survey. To assist personnel in the selection of analytical services, this catalog lists sample volume, required containers, applicable concentration range, detection level, precision of analysis, and preservation requirements for samples.

  15. Sensitivity Analysis and Quality Assessment of Laboratory BRDF Data

    Microsoft Academic Search

    St. Sandmeier; Ch. Müller; B. Hosgood; G. Andreoli

    1998-01-01

    A detailed quality and sensitivity analysis of hyper-spectral BRDF data, acquired under controlled laboratory conditions at the European Goniometric Facility (EGO) of the Joint Research Center, Ispra\\/Italy, has been performed. In regard to bidirectional reflectance measurements in the field with the FIGOS goniometer, the impact of angular data sampling, the movement of the Sun, and the Lambertian assumption of a

  16. MDQC: Mahalanobis Distance Quality Control

    Microsoft Academic Search

    Gabriela V. Cohen Freue; Justin Harrington

    technical problems and seriously damage the quality of the data. Thus, it is essential to identify those arrays with low quality. Our Mahalanobis Distance Quality Control (MDQC) is a multivariate quality assessment method for microarrays that is based on the similarity of quality measures across arrays, i.e., on the idea of outlier detection. Intuitively, the\\

  17. Evaluation of quality-control data collected by the U.S. Geological Survey for routine water-quality activities at the Idaho National Laboratory and vicinity, southeastern Idaho, 2002-08

    USGS Publications Warehouse

    Rattray, Gordon W.

    2014-01-01

    Quality-control (QC) samples were collected from 2002 through 2008 by the U.S. Geological Survey, in cooperation with the U.S. Department of Energy, to ensure data robustness by documenting the variability and bias of water-quality data collected at surface-water and groundwater sites at and near the Idaho National Laboratory. QC samples consisted of 139 replicates and 22 blanks (approximately 11 percent of the number of environmental samples collected). Measurements from replicates were used to estimate variability (from field and laboratory procedures and sample heterogeneity), as reproducibility and reliability, of water-quality measurements of radiochemical, inorganic, and organic constituents. Measurements from blanks were used to estimate the potential contamination bias of selected radiochemical and inorganic constituents in water-quality samples, with an emphasis on identifying any cross contamination of samples collected with portable sampling equipment. The reproducibility of water-quality measurements was estimated with calculations of normalized absolute difference for radiochemical constituents and relative standard deviation (RSD) for inorganic and organic constituents. The reliability of water-quality measurements was estimated with pooled RSDs for all constituents. Reproducibility was acceptable for all constituents except dissolved aluminum and total organic carbon. Pooled RSDs were equal to or less than 14 percent for all constituents except for total organic carbon, which had pooled RSDs of 70 percent for the low concentration range and 4.4 percent for the high concentration range. Source-solution and equipment blanks were measured for concentrations of tritium, strontium-90, cesium-137, sodium, chloride, sulfate, and dissolved chromium. Field blanks were measured for the concentration of iodide. No detectable concentrations were measured from the blanks except for strontium-90 in one source solution and one equipment blank collected in September and October 2004, respectively. The detectable concentrations of strontium-90 in the blanks probably were from a small source of strontium-90 contamination or large measurement variability, or both. Order statistics and the binomial probability distribution were used to estimate the magnitude and extent of any potential contamination bias of tritium, strontium-90, cesium-137, sodium, chloride, sulfate, dissolved chromium, and iodide in water-quality samples. These statistical methods indicated that, with (1) 87 percent confidence, contamination bias of cesium-137 and sodium in 60 percent of water-quality samples was less than the minimum detectable concentration or reporting level; (2) 92?94 percent confidence, contamination bias of tritium, strontium-90, chloride, sulfate, and dissolved chromium in 70 percent of water-quality samples was less than the minimum detectable concentration or reporting level; and (3) 75 percent confidence, contamination bias of iodide in 50 percent of water-quality samples was less than the reporting level for iodide. These results support the conclusion that contamination bias of water-quality samples from sample processing, storage, shipping, and analysis was insignificant and that cross-contamination of perched groundwater samples collected with bailers during 2002–08 was insignificant.

  18. USGS Blind Sample Project: monitoring and evaluating laboratory analytical quality

    USGS Publications Warehouse

    Ludtke, Amy S.; Woodworth, Mark T.

    1997-01-01

    The U.S. Geological Survey (USGS) collects and disseminates information about the Nation's water resources. Surface- and ground-water samples are collected and sent to USGS laboratories for chemical analyses. The laboratories identify and quantify the constituents in the water samples. Random and systematic errors occur during sample handling, chemical analysis, and data processing. Although all errors cannot be eliminated from measurements, the magnitude of their uncertainty can be estimated and tracked over time. Since 1981, the USGS has operated an independent, external, quality-assurance project called the Blind Sample Project (BSP). The purpose of the BSP is to monitor and evaluate the quality of laboratory analytical results through the use of double-blind quality-control (QC) samples. The information provided by the BSP assists the laboratories in detecting and correcting problems in the analytical procedures. The information also can aid laboratory users in estimating the extent that laboratory errors contribute to the overall errors in their environmental data.

  19. Iowa Central Quality Fuel Testing Laboratory

    SciTech Connect

    Heach, Don; Bidieman, Julaine

    2013-09-30

    The objective of this project is to finalize the creation of an independent quality fuel testing laboratory on the campus of Iowa Central Community College in Fort Dodge, Iowa that shall provide the exploding biofuels industry a timely and cost-effective centrally located laboratory to complete all state and federal fuel and related tests that are required. The recipient shall work with various state regulatory agencies, biofuel companies and state and national industry associations to ensure that training and testing needs of their members and American consumers are met. The recipient shall work with the Iowa Department of Ag and Land Stewardship on the development of an Iowa Biofuel Quality Standard along with the Development of a standard that can be used throughout industry.

  20. Quality Assurance of RNA Expression Profiling in Clinical Laboratories

    PubMed Central

    Tang, Weihua; Hu, Zhiyuan; Muallem, Hind; Gulley, Margaret L.

    2012-01-01

    RNA expression profiles are increasingly used to diagnose and classify disease, based on expression patterns of as many as several thousand RNAs. To ensure quality of expression profiling services in clinical settings, a standard operating procedure incorporates multiple quality indicators and controls, beginning with preanalytic specimen preparation and proceeding thorough analysis, interpretation, and reporting. Before testing, histopathological examination of each cellular specimen, along with optional cell enrichment procedures, ensures adequacy of the input tissue. Other tactics include endogenous controls to evaluate adequacy of RNA and exogenous or spiked controls to evaluate run- and patient-specific performance of the test system, respectively. Unique aspects of quality assurance for array-based tests include controls for the pertinent outcome signatures that often supersede controls for each individual analyte, built-in redundancy for critical analytes or biochemical pathways, and software-supported scrutiny of abundant data by a laboratory physician who interprets the findings in a manner facilitating appropriate medical intervention. Access to high-quality reagents, instruments, and software from commercial sources promotes standardization and adoption in clinical settings, once an assay is vetted in validation studies as being analytically sound and clinically useful. Careful attention to the well-honed principles of laboratory medicine, along with guidance from government and professional groups on strategies to preserve RNA and manage large data sets, promotes clinical-grade assay performance. PMID:22020152

  1. Total quality control in education

    Microsoft Academic Search

    Zhongming Liang

    1991-01-01

    Some quality problems in American higher education are addressed. The author suggests that the concept of total quality control (TQC), a philosophy in manufacturing management, be applied to education in order to achieve changes from a more individualized control to a more systemized control. He discusses some particular methods for TQC in teaching. He suggests team work for course content

  2. Multivariate approach to quality control in clinical chemistry

    Microsoft Academic Search

    Jerry Dechert; Kenneth E. Case

    1998-01-01

    When monitoring analyzer performance in the clinical setting, laboratories are required to test multiple con- centrations of control material on a daily basis. Because of the nature of laboratory testing, there is the potential for correlation between the concentrations of control material being monitored. Although traditional clinical quality-control approaches make an underlying as- sumption of independence with respect to the

  3. SIMBAD quality-control

    NASA Technical Reports Server (NTRS)

    Lesteven, Soizick

    1992-01-01

    The astronomical database SIMBAD developed at the Centre de donnees astronomiques de Strasbourg presently contains 760,000 objects (stellar and non-stellar). It has the unique characteristic of being structured specifically for astronomical objects. All types of heterogeneous data (bibliographic references, measurements, and sets of identification) are connected with each object. The attributes that define quality of the database include the following. Reliability: cross-identification should not rely upon just exact values object coordinates. It also means that information attached to one simple object should be consistent. The existing data must be controlled in order to start with a reliable base and to cross-identify new data assuring the quality as data grows. Exhaustivity: delays between publication of new informations and their inclusion in the database should be as short as possible. The integrity of the database has to be maintained as data accumulates. Taking the amount of data into consideration and the rate of new data production, it is necessary to use automatic methods. One of the possibilities is to use multivariate data analysis. The factor-space is a n-dimensional relevancy space which is described by the n-axes representing a set of n subject matter headings; the words and phrases can be used to scale the axes and the documents are then a vector average of the terms within them. The application reported herein is based on the NASA-STI bibliographical database. The selected data concern astronomy, astrophysics, and space radiation (102,963 references from 1975 to 1991 included 8070 keywords). The F-space is built from this bibliographical data. By comparing the F-space position obtained from the NASA-STI keywords with the F-space position obtained from the SIMBAD references, the authors will be able to show whether it is possible to retrieve information with a restricted set of words only. If the comparison is valid, this will be a way to enter bibliographic information in the SIMBAD quality control process. Furthermore, it is possible to connect the physical measurements of stars from SIMBAD to literature concerning these stars from the NASA-STI abstracts. The physical properties of stars (e.g. UBV colors) are not randomly distributed. Stars are distributed among different clusters in a physical parameter space. The authors will show that there are some relations between this classification and the literature concerning these objects clusters in a factor space. They will investigate the nature of the relationship between the SIMBAD measurements and the bibliography. These would be new relationships that are not pre-established by an astronomer. In addition, the bibliography could be neutral information that can be used in combination with the measured parameters.

  4. Quality for Productivity through Quality Control Circles.

    ERIC Educational Resources Information Center

    Khatib, Ruslan Bin

    1985-01-01

    Describes two Malaysian organizations that the government has appointed to spearhead the dissemination of the QCC (quality control circles) concept and activities: The National Productivity Center and the National Institute of Public Administration. The author also examines the basic concepts of the QCC in Malaysia. (CT)

  5. The Albuquerque Seismological Laboratory Data Quality Analyzer

    NASA Astrophysics Data System (ADS)

    Ringler, A. T.; Hagerty, M.; Holland, J.; Gee, L. S.; Wilson, D.

    2013-12-01

    The U.S. Geological Survey's Albuquerque Seismological Laboratory (ASL) has several efforts underway to improve data quality at its stations. The Data Quality Analyzer (DQA) is one such development. The DQA is designed to characterize station data quality in a quantitative and automated manner. Station quality is based on the evaluation of various metrics, such as timing quality, noise levels, sensor coherence, and so on. These metrics are aggregated into a measurable grade for each station. The DQA consists of a website, a metric calculator (Seedscan), and a PostgreSQL database. The website allows the user to make requests for various time periods, review specific networks and stations, adjust weighting of the station's grade, and plot metrics as a function of time. The website dynamically loads all station data from a PostgreSQL database. The database is central to the application; it acts as a hub where metric values and limited station descriptions are stored. Data is stored at the level of one sensor's channel per day. The database is populated by Seedscan. Seedscan reads and processes miniSEED data, to generate metric values. Seedscan, written in Java, compares hashes of metadata and data to detect changes and perform subsequent recalculations. This ensures that the metric values are up to date and accurate. Seedscan can be run in a scheduled task or on demand by way of a config file. It will compute metrics specified in its configuration file. While many metrics are currently in development, some are completed and being actively used. These include: availability, timing quality, gap count, deviation from the New Low Noise Model, deviation from a station's noise baseline, inter-sensor coherence, and data-synthetic fits. In all, 20 metrics are planned, but any number could be added. ASL is actively using the DQA on a daily basis for station diagnostics and evaluation. As Seedscan is scheduled to run every night, data quality analysts are able to then use the website to diagnose changes in noise levels or other anomalous data. This allows for errors to be corrected quickly and efficiently. The code is designed to be flexible for adding metrics and portable for use in other networks. We anticipate further development of the DQA by improving the existing web-interface, adding more metrics, adding an interface to facilitate the verification of historic station metadata and performance, and an interface to allow better monitoring of data quality goals.

  6. Current Quality Culture Mini Paper Six Sigma Quality Control

    E-print Network

    Vardeman, Stephen B.

    Current Quality Culture Mini Paper Six Sigma Quality Control By: Shawn Higbee Steve Soseman Kaya expression created by Phillip Crosby as a synonym for a quality control standard that was so rigid (www.mpcps.con/SIX0.html). So what exactly is 6 quality control...? It is quality control standard

  7. Cost Effectiveness of Adopted Quality Requirements in Hospital Laboratories

    PubMed Central

    HAMZA, Alneil; AHMED-ABAKUR, Eltayib; ABUGROUN, Elsir; BAKHIT, Siham; HOLI, Mohamed

    2013-01-01

    Background The present study was designed in quasi-experiment to assess adoption of the essential clauses of particular clinical laboratory quality management requirements based on international organization for standardization (ISO 15189) in hospital laboratories and to evaluate the cost effectiveness of compliance to ISO 15189. Methods: The quality management intervention based on ISO 15189 was conceded through three phases; pre – intervention phase, Intervention phase and Post-intervention phase. Results: In pre-intervention phase the compliance to ISO 15189 was 49% for study group vs. 47% for control group with P value 0.48, while the post intervention results displayed 54% vs. 79% for study group and control group respectively in compliance to ISO 15189 and statistically significant difference (P value 0.00) with effect size (Cohen’s d) of (0.00) in pre-intervention phase and (0.99) in post – intervention phase. The annual average cost per-test for the study group and control group was 1.80 ± 0.25 vs. 1.97 ± 0.39, respectively with P value 0.39 whereas the post-intervention results showed that the annual average total costs per-test for study group and control group was 1.57 ± 0.23 vs 2.08 ± 0.38, P value 0.019 respectively, with cost-effectiveness ratio of (0.88) in pre -intervention phase and (0.52) in post-intervention phase. Conclusion: The planned adoption of quality management requirements (QMS) in clinical laboratories had great effect to increase the compliance percent with quality management system requirement, raise the average total cost effectiveness, and improve the analytical process capability of the testing procedure. PMID:23967422

  8. Clinical Laboratory Quality Practices When Hemolysis Occurs.

    PubMed

    Howanitz, Peter J; Lehman, Christopher M; Jones, Bruce A; Meier, Frederick A; Horowitz, Gary L

    2015-07-01

    Context .- Hemolyzed specimens delay clinical laboratory results, proliferate unnecessary testing, complicate physician decisions, injure patients indirectly, and increase health care costs. Objective .- To determine quality improvement practices when hemolysis occurs. Design .- We used the College of American Pathologists (CAP) Survey Program to distribute a Q-Probes-type questionnaire about hemolysis practices to CAP Chemistry Survey participants. Results .- Of 3495 participants sent the questionnaire, 846 (24%) responded. Although 85%, 69%, and 55% of participants had written hemolysis policies for potassium, lactate dehydrogenase, and glucose, respectively, only a few (46%, 40%, and 40%) had standardized hemolysis reports between their primary and secondary chemistry analyzers for these 3 analytes. Most participants (70%) had not attempted to validate the manufacturers' hemolysis data for these 3 analytes; however, essentially all who tried, succeeded. Forty-nine percent of participants had taken corrective action to reduce hemolysis during the past year and used, on average, 2.4 different actions, with collection and distribution of hemolysis data to administrative leadership (57%), troubleshooting outliers (55%), retraining phlebotomist (53%), and establishment of quality improvement teams among the laboratory and at problem locations (37%) being the most common actions. When asked to assess their progress in reducing hemolysis, 70% noted slow to no progress, and 2% gave up on improvement. Upon measuring potassium, lactate dehydrogenase, and glucose, approximately 60% of participants used the same specimen flag for hemolysis as for lipemia and icterus. Conclusions .- Hemolysis decreases the quality and increases the cost of health care. Practices for measuring, reporting, and decreasing hemolysis rates need improvement. PMID:26125430

  9. Quality assurance of laboratory work and clinical use of laboratory tests in general practice in Norway: A survey

    PubMed Central

    Thue, Geir; Jevnaker, Marianne; Gulstad, Guri Andersen; Sandberg, Sverre

    2011-01-01

    Objective Virtually all the general practices in Norway participate in the Norwegian Quality Improvement of Laboratory Services in Primary Care, NOKLUS. In order to assess and develop NOKLUS's services, it was decided to carry out an investigation in the largest participating group, general practices. Design In autumn 2008 a questionnaire was sent to all Norwegian general practices asking for feedback on different aspects of NOKLUS's main services: contact with medical laboratory technologists, sending of control materials, use and maintenance of practice-specific laboratory binders, courses, and testing of laboratory equipment. In addition, attitudes were elicited towards possible new services directed at assessing other technical equipment and clinical use of tests. Results Responses were received from 1290 of 1552 practices (83%). The great majority thought that the frequency of sending out control material should continue as at present, and they were pleased with the feedback reports and follow-up by the laboratory technologists in the counties. Even after many years of practical experience, there is still a need to update laboratory knowledge through visits to practices, courses, and written information. Practices also wanted quality assurance of blood pressure meters and spirometers, and many doctors wanted feedback on their use of laboratory tests. Conclusion Services regarding quality assurance of point-of-care tests, guidance, and courses should be continued. Quality assurance of other technical equipment and of the doctor's clinical use of laboratory tests should be established as part of comprehensive quality assurance. PMID:21740334

  10. Evaluation of quality-control data collected by the U.S. Geological Survey for routine water-quality activities at the Idaho National Laboratory, Idaho, 1996–2001

    USGS Publications Warehouse

    Rattray, Gordon W.

    2012-01-01

    The U.S. Geological Survey, in cooperation with the U.S. Department of Energy, collects surface water and groundwater samples at and near the Idaho National Laboratory as part of a routine, site-wide, water-quality monitoring program. Quality-control samples are collected as part of the program to ensure and document the quality of environmental data. From 1996 to 2001, quality-control samples consisting of 204 replicates and 27 blanks were collected at sampling sites. Paired measurements from replicates were used to calculate variability (as reproducibility and reliability) from sample collection and analysis of radiochemical, chemical, and organic constituents. Measurements from field and equipment blanks were used to estimate the potential contamination bias of constituents. The reproducibility of measurements of constituents was calculated from paired measurements as the normalized absolute difference (NAD) or the relative standard deviation (RSD). The NADs and RSDs, as well as paired measurements with censored or estimated concentrations for which NADs and RSDs were not calculated, were compared to specified criteria to determine if the paired measurements had acceptable reproducibility. If the percentage of paired measurements with acceptable reproducibility for a constituent was greater than or equal to 90 percent, then the reproducibility for that constituent was considered acceptable. The percentage of paired measurements with acceptable reproducibility was greater than or equal to 90 percent for all constituents except orthophosphate (89 percent), zinc (80 percent), hexavalent chromium (53 percent), and total organic carbon (TOC; 38 percent). The low reproducibility for orthophosphate and zinc was attributed to calculation of RSDs for replicates with low concentrations of these constituents. The low reproducibility for hexavalent chromium and TOC was attributed to the inability to preserve hexavalent chromium in water samples and high variability with the analytical method for TOC. The reliability of measurements of constituents was estimated from pooled RSDs that were calculated for discrete concentration ranges for each constituent. Pooled RSDs of 15 to 33 percent were calculated for low concentrations of gross-beta radioactivity, strontium-90, ammonia, nitrite, orthophosphate, nickel, selenium, zinc, tetrachloroethene, and toluene. Lower pooled RSDs of 0 to 12 percent were calculated for all other concentration ranges of these constituents, and for all other constituents, except for one concentration range for gross-beta radioactivity, chloride, and nitrate + nitrite; two concentration ranges for hexavalent chromium; and TOC. Pooled RSDs for the 50 to 60 picocuries per liter concentration range of gross-beta radioactivity (reported as cesium-137) and the 10 to 60 milligrams per liter (mg/L) concentration range of nitrate + nitrite (reported as nitrogen [N]) were 17 percent. Chloride had a pooled RSD of 14 percent for the 20 to less than 60 mg/L concentration range. High pooled RSDs of 40 and 51 percent were calculated for two concentration ranges for hexavalent chromium and of 60 percent for TOC. Measurements from (1) field blanks were used to estimate the potential bias associated with environmental samples from sample collection and analysis, (2) equipment blanks were used to estimate the potential bias from cross contamination of samples collected from wells where portable sampling equipment was used, and (3) a source-solution blank was used to verify that the deionized water source-solution was free of the constituents of interest. If more than one measurement was available, the bias was estimated using order statistics and the binomial probability distribution. The source-solution blank had a detectable concentration of hexavalent chromium of 2 micrograms per liter. If this bias was from a source other than the source solution, then about 84 percent of the 117 hexavalent chromium measurements from environmental samples could have a bias of 10 percent or more. Of the 14 field blanks that were collected,

  11. Principles and Practices for Quality Assurance and Quality Control

    USGS Publications Warehouse

    Jones, Berwyn E.

    1999-01-01

    Quality assurance and quality control are vital parts of highway runoff water-quality monitoring projects. To be effective, project quality assurance must address all aspects of the project, including project management responsibilities and resources, data quality objectives, sampling and analysis plans, data-collection protocols, data quality-control plans, data-assessment procedures and requirements, and project outputs. Quality control ensures that the data quality objectives are achieved as planned. The historical development and current state of the art of quality assurance and quality control concepts described in this report can be applied to evaluation of data from prior projects.

  12. The role of laboratory information systems in healthcare quality improvement

    Microsoft Academic Search

    Jeffrey P. Harrison; Geoffrey M. McDowell

    2008-01-01

    Purpose – The purpose of this study was to evaluate the status of US hospital Laboratory Information Systems. Laboratory Information Systems are critical to high quality healthcare service provision. Data show that the need for these systems is growing to meet accompanying technological and workload demands. Additionally, laboratory tests provide the majority of information for clinical decision-making. Laboratory processes automation,

  13. Method of analysis at the U.S. Geological Survey California Water Science Center, Sacramento Laboratory - determination of haloacetic acid formation potential, method validation, and quality-control practices

    USGS Publications Warehouse

    Zazzi, Barbara C.; Crepeau, Kathryn L.; Fram, Miranda S.; Bergamaschi, Brian A.

    2005-01-01

    An analytical method for the determination of haloacetic acid formation potential of water samples has been developed by the U.S. Geological Survey California Water Science Center Sacramento Laboratory. The haloacetic acid formation potential is measured by dosing water samples with chlorine under specified conditions of pH, temperature, incubation time, darkness, and residual-free chlorine. The haloacetic acids formed are bromochloroacetic acid, bromodichloroacetic acid, dibromochloroacetic acid, dibromoacetic acid, dichloroacetic acid, monobromoacetic acid, monochloroacetic acid, tribromoacetic acid, and trichloroacetic acid. They are extracted, methylated, and then analyzed using a gas chromatograph equipped with an electron capture detector. Method validation experiments were performed to determine the method accuracy, precision, and detection limit for each of the compounds. Method detection limits for these nine haloacetic acids ranged from 0.11 to 0.45 microgram per liter. Quality-control practices include the use of blanks, quality-control samples, calibration verification standards, surrogate recovery, internal standard, matrix spikes, and duplicates.

  14. Distance learning applied to control engineering laboratories

    Microsoft Academic Search

    B. Aktan; C. A. Bohus; L. A. Crowl; M. H. Shor

    1996-01-01

    Distance learning is an emerging paradigm where students, teachers, and equipment may be at different geographic locations. At the College of Engineering of Oregon State University, we have developed and demonstrated an innovative real-time remote-access control engineering teaching laboratory. Our remote laboratory uses the Internet to provide complete access to the usual laboratory facilities. In addition, remote power control, network

  15. Method of Analysis by the U.S. Geological Survey California District Sacramento Laboratory?Determination of Trihalomethane Formation Potential, Method Validation, and Quality-Control Practices

    USGS Publications Warehouse

    Crepeau, Kathryn L.; Fram, Miranda S.; Bush, Noel

    2004-01-01

    An analytical method for the determination of the trihalomethane formation potential of water samples has been developed. The trihalomethane formation potential is measured by dosing samples with chlorine under specified conditions of pH, temperature, incubation time, darkness, and residual-free chlorine, and then analyzing the resulting trihalomethanes by purge and trap/gas chromatography equipped with an electron capture detector. Detailed explanations of the method and quality-control practices are provided. Method validation experiments showed that the trihalomethane formation potential varies as a function of time between sample collection and analysis, residual-free chlorine concentration, method of sample dilution, and the concentration of bromide in the sample.

  16. Method of Analysis by the U.S. Geological Survey California District Sacramento Laboratory-- Determination of Dissolved Organic Carbon in Water by High Temperature Catalytic Oxidation, Method Validation, and Quality-Control Practices

    USGS Publications Warehouse

    Bird, Susan M.; Fram, Miranda S.; Crepeau, Kathryn L.

    2003-01-01

    An analytical method has been developed for the determination of dissolved organic carbon concentration in water samples. This method includes the results of the tests used to validate the method and the quality-control practices used for dissolved organic carbon analysis. Prior to analysis, water samples are filtered to remove suspended particulate matter. A Shimadzu TOC-5000A Total Organic Carbon Analyzer in the nonpurgeable organic carbon mode is used to analyze the samples by high temperature catalytic oxidation. The analysis usually is completed within 48 hours of sample collection. The laboratory reporting level is 0.22 milligrams per liter.

  17. 42 CFR 493.1239 - Standard: General laboratory systems quality assessment.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...2012-10-01 false Standard: General laboratory systems quality assessment. 493... STANDARDS AND CERTIFICATION LABORATORY REQUIREMENTS Quality System for Nonwaived Testing General Laboratory Systems § 493.1239...

  18. 42 CFR 493.1239 - Standard: General laboratory systems quality assessment.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...2014-10-01 false Standard: General laboratory systems quality assessment. 493... STANDARDS AND CERTIFICATION LABORATORY REQUIREMENTS Quality System for Nonwaived Testing General Laboratory Systems § 493.1239...

  19. 42 CFR 493.1239 - Standard: General laboratory systems quality assessment.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...2013-10-01 false Standard: General laboratory systems quality assessment. 493... STANDARDS AND CERTIFICATION LABORATORY REQUIREMENTS Quality System for Nonwaived Testing General Laboratory Systems § 493.1239...

  20. Quality Assurance as Pedagogy for Academic Forensic Anthropology Laboratories

    Microsoft Academic Search

    Michael W. Warren; Traci Van Deest; Kristina Ballard

    2011-01-01

    A surety-based quality assurance program is the hallmark of an efficient and reliable forensic laboratory, as well as a basic requirement for accreditation and\\/or certification. Most forensic laboratories are staffed by professional scientists who have completed their education and training. However, many, if not most, forensic anthropology laboratories are placed in academic institutions in which graduate education is a primary

  1. Quality control during IC processing

    NASA Technical Reports Server (NTRS)

    1979-01-01

    Manual gives detailed test procedures for controlling silicon-wafer processing in manufacture of integrated circuits. Included among 43 test procedures are: ionic, bacterial, and solids contamination of high-purity water needed for wafer processing; crystallographic reflection, purity, and orientation; substrate dimensions and finish; thickness of deposited epitaxial films; oxide quality; photoresist characteristics; pinholes in insulating layers; metallized adhesion; and quality of ohmic contact.

  2. 1994 ASEE Conference Proceedings A Laboratory-Based Course in Process Quality

    E-print Network

    Lamancusa, John S.

    are two indicators of this development. There is an increased focus on customer satisfaction, quality1994 ASEE Conference Proceedings -1- A Laboratory-Based Course in Process Quality Engineering intervals, statistical process control, regression models and the design of experiments (DOE). These topics

  3. Laboratory quality assurance and its role in the safeguards analytical laboratory evaluation (SALE) program

    Microsoft Academic Search

    W. L. Delvin; C. E. Pietri

    1981-01-01

    Since the late 1960's, strong emphasis has been given to quality assurance in the nuclear industry, particularly to that part involved in nuclear reactors. This emphasis has had impact on the analytical chemistry laboratory because of the importance of analytical measurements in the certification and acceptance of materials used in the fabrication and construction of reactor components. Laboratory quality assurance,

  4. Quality control of herbal medicines

    Microsoft Academic Search

    Yi-Zeng Liang; Peishan Xie; Kelvin Chan

    2004-01-01

    Different chromatographic and electrophoretic techniques commonly used in the instrumental inspection of herbal medicines (HM) are first comprehensively reviewed. Chemical fingerprints obtained by chromatographic and electrophoretic techniques, especially by hyphenated chromatographies, are strongly recommended for the purpose of quality control of herbal medicines, since they might represent appropriately the “chemical integrities” of the herbal medicines and therefore be used for

  5. Quality control in databanks for molecular biology

    E-print Network

    Sussman, Joel L.

    Quality control in databanks for molecular biology CODATA Task Group on Biological Macromolecules surveyed quality control procedures of archival databanks in molecular biology. Our role is `to advise. Quality control procedures provide the second level of protection. Indices of quality, even if they do

  6. Quality control of EUVE databases

    NASA Technical Reports Server (NTRS)

    John, L. M.; Drake, J.

    1992-01-01

    The publicly accessible databases for the Extreme Ultraviolet Explorer include: the EUVE Archive mailserver; the CEA ftp site; the EUVE Guest Observer Mailserver; and the Astronomical Data System node. The EUVE Performance Assurance team is responsible for verifying that these public EUVE databases are working properly, and that the public availability of EUVE data contained therein does not infringe any data rights which may have been assigned. In this poster, we describe the Quality Assurance (QA) procedures we have developed from the approach of QA as a service organization, thus reflecting the overall EUVE philosophy of Quality Assurance integrated into normal operating procedures, rather than imposed as an external, post facto, control mechanism.

  7. A quality manual for the clinical laboratory including the elements of a quality system. Proposed guidelines.

    PubMed

    Dybkaer, R; Jordal, R; Jørgensen, P J; Hansson, P; Hjelm, M; Kaihola, H L; Kallner, A; Rustad, P; Uldall, A; de Verdier, C H

    1993-01-01

    Development of quality manuals is a means for the promotion of quality in clinical laboratories by describing the total quality system. It also provides opportunity of checking whether the quality system is implemented in reality and demonstrates to the hospital administration and the clinicians that the laboratory is committed to quality. The intention of these guidelines is to describe the elements of the quality system for a large clinical laboratory, and to present such a system in the form of a quality manual. The proposed guidelines comply, where relevant, with ISO/IEC guide 25 'General requirements for the technical competence of testing laboratories' and EN 45001 'General criteria for the operation of testing laboratories'. The document may be used as an aid for laboratories wishing to be accredited according to EN 45001, or intending to apply for formal certification of their quality systems, according to ISO 9001 'Quality systems--Model for quality assurance in design/development, production, installation, and servicing' utilizing ISO 9004 'Quality management and quality system elements--guidelines; Part 2 Guidelines for service'. However, information about the minimum requirements for official recognition should be obtained from the particular accreditation or certification body concerned. PMID:8465158

  8. Experiences in establishing a PEPFAR-supported laboratory quality system in Nigeria.

    PubMed

    Abimiku, Alash'le G; Croxton, Talishiea; Akintunde, Ezekiel; Okelade, Bimpe; Jugu, Joseph; Peters, Sam; Dakum, Patrick; Blattner, William; Constantine, Niel

    2010-10-01

    The need to accurately diagnose HIV-infected persons and monitor their immune status and sequelae from increased access to antiretroviral therapy dictated the establishment of a quality assurance (QA) system supported by dedicated personnel, financial resources, and a close monitoring system. Assessment of laboratories and personnel in Nigeria revealed the need for improved laboratory infrastructure and training, including on-site didactic and wet workshops and the institution of a tiered QA unit of laboratory regional officers, focal persons, and site monitors who provided guidance and continuous monitoring. Quarterly assessments and generated reports guided corrective actions. A sustainable quality laboratory system was developed for the first time in Nigeria with funding from the US President's Emergency Plan for AIDS Relief. With expansion from 7 to 34 comprehensive treatment sites, a tiered laboratory organizational structure with regional and site-based Nigerian quality control officers was developed. Measured improvements included reduction in deficiencies from 13% to 2%. PMID:20855634

  9. Quality Assurance/Quality Control Jobs

    NASA Astrophysics Data System (ADS)

    Fanslau, Melody; Young, Janelle

    The production of a quality and safe food product is essential to the success of any food manufacturing facility. Because of this great importance, a career in quality can be extremely rewarding. Without happy customers willing to buy a product, a company would not be able to survive. Quality issues such as foreign objects, spoiled or mislabeled product, failure to meet net weight requirements, or a recall can all turn customers away from buying a product. The food industry is a customer-driven market in which some consumers are brand loyal based on a history of high quality or in which a single bad experience with a product will turn them away for a lifetime. With this said, the main role of a quality department is to help ensure that quality issues such as these are eliminated or kept to a minimum to maintain or increase the number of customers purchasing their product.

  10. Approaches to quality management and accreditation in a genetic testing laboratory

    PubMed Central

    Berwouts, Sarah; Morris, Michael A; Dequeker, Elisabeth

    2010-01-01

    Medical laboratories, and specifically genetic testing laboratories, provide vital medical services to different clients: clinicians requesting a test, patients from whom the sample was collected, public health and medical-legal instances, referral laboratories and authoritative bodies. All expect results that are accurate and obtained in an efficient and effective manner, within a suitable time frame and at acceptable cost. There are different ways of achieving the end results, but compliance with International Organization for Standardization (ISO) 15189, the international standard for the accreditation of medical laboratories, is becoming progressively accepted as the optimal approach to assuring quality in medical testing. We present recommendations and strategies designed to aid genetic testing laboratories with the implementation of a quality management system, including key aspects such as document control, external quality assessment, internal quality control, internal audit, management review, validation, as well as managing the human side of change. The focus is on pragmatic approaches to attain the levels of quality management and quality assurance required for accreditation according to ISO 15189, within the context of genetic testing. Attention is also given to implementing efficient and effective quality improvement. PMID:20720559

  11. Thoughts on quality-control systems: a laboratorian's perspective

    Microsoft Academic Search

    George S. Cembrowski

    State-of-the-art prospective quality-control systems en- tail the use of medically relevant, analyte-specific qual- ity control limits. With analyte-specific limits broader than those generally used in the clinical laboratory, there will be fewer false rejections, fewer unnecessary reanalyses, and shorter delays in run reporting. If the analyte-specific limits are narrower than those used in the laboratory, more errors will be detected,

  12. Quality Control of Meteorological Observations

    NASA Technical Reports Server (NTRS)

    Collins, William; Dee, Dick; Rukhovets, Leonid

    1999-01-01

    For the first time, a problem of the meteorological observation quality control (QC) was formulated by L.S. Gandin at the Main Geophysical Observatory in the 70's. Later in 1988 L.S. Gandin began adapting his ideas in complex quality control (CQC) to the operational environment at the National Centers for Environmental Prediction. The CQC was first applied by L.S.Gandin and his colleagues to detection and correction of errors in rawinsonde heights and temperatures using a complex of hydrostatic residuals.Later, a full complex of residuals, vertical and horizontal optimal interpolations and baseline checks were added for the checking and correction of a wide range of meteorological variables. some other of Gandin's ideas were applied and substantially developed at other meteorological centers. A new statistical QC was recently implemented in the Goddard Data Assimilation System. The central component of any quality control is a buddy check which is a test of individual suspect observations against available nearby non-suspect observations. A novel feature of this test is that the error variances which are used for QC decision are re-estimated on-line. As a result, the allowed tolerances for suspect observations can depend on local atmospheric conditions. The system is then better able to accept extreme values observed in deep cyclones, jet streams and so on. The basic statements of this adaptive buddy check are described. Some results of the on-line QC including moisture QC are presented.

  13. Carcinogen Control in the Chemical Laboratory.

    ERIC Educational Resources Information Center

    Johnson, James S.

    1981-01-01

    Presents general and specific guidelines for handling carcinogens. Additional topics include: definition of potential occupational carcinogens; classification of carcinogens; inventory requirements; signs and labels for materials and laboratories; decontamination and disposal procedures; medical surveillance for employees working with controlled

  14. New laboratory tools in the assessment of bone quality

    Microsoft Academic Search

    D. Chappard; M. F. Baslé; E. Legrand; M. Audran

    2011-01-01

    Bone quality is a complex set of intricated and interdependent factors that influence bone strength. A number of methods have\\u000a emerged to measure bone quality, taking into account the organic or the mineral phase of the bone matrix, in the laboratory.\\u000a Bone quality is a complex set of different factors that are interdependent. The bone matrix organization can be described

  15. 14 CFR 21.139 - Quality control.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...AIRCRAFT CERTIFICATION PROCEDURES FOR PRODUCTS AND PARTS Production Certificates § 21.139 Quality control. The applicant must show...a quality control system for any product, for which he requests a...

  16. Quality Control Procedures Applied to Drifter Data

    E-print Network

    Drifter Data Assembly Center Revised December 2003 Quality Control Procedures Applied to Drifter transmitting, and QC data Decodes raw data & applies calibrations Quality controls and interpolates data Makes Jessica Redman #12;Drifter DAC Objective "Our goal is to assemble and provide uniform quality controlled

  17. Cell culture quality control by rapid isoenzymatic characterization.

    PubMed

    Halton, D M; Peterson, W D; Hukku, B

    1983-01-01

    Procedures that involve cell cultures require careful quality control to avoid inter- and intraspecies contamination. We have developed an electrophoresis technique that can be used routinely in cell culture laboratories to monitor cell line integrity. The method involves the isoenzymatic separation of nine polymorphic enzymes, three of which can be used for cell line species determinations and seven of which can be used for human cell line characterizations. Examples of how the system has been applied to both inter- and intraspecies identifications are described. The routine application of this protocol would be a valuable asset for laboratories concerned with establishing effective cell culture quality control. PMID:6401685

  18. Advanced Power Systems and Controls Laboratory

    E-print Network

    Ben-Yakar, Adela

    and development facility for the evaluation of algorithms and components for the XP-DPR, an integrated BESS systemAdvanced Power Systems and Controls Laboratory Battery Energy Storage for Enabling Distributed increase the value of energy generated. The control system for the BESS must be coupled to the renewable

  19. Quality assurance and quality control in monitoring programs

    USGS Publications Warehouse

    Shampine, W.J.

    1993-01-01

    There are three general characteristics of the data to be collected in a monitoring program that should be met in order to maximize the use and value of the data: the data quality should be known the data type and quality should be consistent and comparable, and the data should be available and accessible. Potential problems with each of these characteristics are addressed effectively by quality assurance and quality control. One of the most important aspects of quality assurance in a monitoring program is the development of a quality assurance plan, which should identify clearly the quality of the data needed and describe in detail the planned actions to provide confidence that the program will meet its stated objectives. Quality control data, which allow for the quality and suitability of the environmental data to be evaluated and ascertained, should be collected and utilized as an integral part of the QA effort associated with a monitoring program.

  20. Analytical Chemistry Laboratory Quality Assurance Project Plan for the Transuranic Waste Characterization Program

    SciTech Connect

    Sailer, S.J.

    1996-08-01

    This Quality Assurance Project Plan (QAPJP) specifies the quality of data necessary and the characterization techniques employed at the Idaho National Engineering Laboratory (INEL) to meet the objectives of the Department of Energy (DOE) Waste Isolation Pilot Plant (WIPP) Transuranic Waste Characterization Quality Assurance Program Plan (QAPP) requirements. This QAPJP is written to conform with the requirements and guidelines specified in the QAPP and the associated documents referenced in the QAPP. This QAPJP is one of a set of five interrelated QAPjPs that describe the INEL Transuranic Waste Characterization Program (TWCP). Each of the five facilities participating in the TWCP has a QAPJP that describes the activities applicable to that particular facility. This QAPJP describes the roles and responsibilities of the Idaho Chemical Processing Plant (ICPP) Analytical Chemistry Laboratory (ACL) in the TWCP. Data quality objectives and quality assurance objectives are explained. Sample analysis procedures and associated quality assurance measures are also addressed; these include: sample chain of custody; data validation; usability and reporting; documentation and records; audits and 0385 assessments; laboratory QC samples; and instrument testing, inspection, maintenance and calibration. Finally, administrative quality control measures, such as document control, control of nonconformances, variances and QA status reporting are described.

  1. Implementation of Good Clinical Laboratory Practice (GCLP) guidelines within the External Quality Assurance Program Oversight Laboratory (EQAPOL).

    PubMed

    Todd, Christopher A; Sanchez, Ana M; Garcia, Ambrosia; Denny, Thomas N; Sarzotti-Kelsoe, Marcella

    2014-07-01

    The EQAPOL contract was awarded to Duke University to develop and manage global proficiency testing programs for flow cytometry-, ELISpot-, and Luminex bead-based assays (cytokine analytes), as well as create a genetically diverse panel of HIV-1 viral cultures to be made available to National Institutes of Health (NIH) researchers. As a part of this contract, EQAPOL was required to operate under Good Clinical Laboratory Practices (GCLP) that are traditionally used for laboratories conducting endpoint assays for human clinical trials. EQAPOL adapted these guidelines to the management of proficiency testing programs while simultaneously incorporating aspects of ISO/IEC 17043 which are specifically designed for external proficiency management. Over the first two years of the contract, the EQAPOL Oversight Laboratories received training, developed standard operating procedures and quality management practices, implemented strict quality control procedures for equipment, reagents, and documentation, and received audits from the EQAPOL Central Quality Assurance Unit. GCLP programs, such as EQAPOL, strengthen a laboratory's ability to perform critical assays and provide quality assessments of future potential vaccines. PMID:24120573

  2. Poorer sleep quality is associated with lower emotion-regulation ability in a laboratory paradigm.

    PubMed

    Mauss, Iris B; Troy, Allison S; LeBourgeois, Monique K

    2013-01-01

    Theoretical models suggest a positive relationship between sleep quality and individuals' ability to regulate emotion. However, few studies have empirically tested this hypothesised link using standardised laboratory measures of emotion-regulation ability. The present research examined the relationship between sleep quality and the ability to implement a type of emotion regulation that has particularly important implications for psychological health: cognitive reappraisal (cognitively reframing an emotional event so as to dampen its impact). To do so, 156 participants (86 male) reported on their past week's sleep quality. Their ability to implement cognitive reappraisal (CRA) was then measured with a standardised laboratory challenge. Participants with poorer self-reported sleep quality exhibited lower CRA, even after controlling for fourteen potential key confounds (e.g., age, negative affect, mood disorder symptoms, stress). This finding is consistent with the idea that poorer sleep quality impairs individuals' ability to engage in the crucial task of regulating negative emotions. PMID:23025547

  3. Testing a Constrained MPC Controller in a Process Control Laboratory

    ERIC Educational Resources Information Center

    Ricardez-Sandoval, Luis A.; Blankespoor, Wesley; Budman, Hector M.

    2010-01-01

    This paper describes an experiment performed by the fourth year chemical engineering students in the process control laboratory at the University of Waterloo. The objective of this experiment is to test the capabilities of a constrained Model Predictive Controller (MPC) to control the operation of a Double Pipe Heat Exchanger (DPHE) in real time.…

  4. NASA Laboratory Telerobotic Manipulator control system architecture

    NASA Technical Reports Server (NTRS)

    Rowe, J. C.; Butler, P. L.; Glassell, R. L.; Herndon, J. N.

    1992-01-01

    In support of the National Aeronautics and Space Administration (NASA) goals to increase the utilization of dexterous robotic systems in space, the Oak Ridge National Laboratory (ORNL) has developed the Laboratory Telerobotic Manipulator (LTM) system. It is a dexterous, dual-arm, force reflecting teleoperator system with robotic features for NASA ground-based research. This paper describes the overall control system architecture, including both the hardware and software. The control system is a distributed, modular, and hierarchical design with flexible expansion capabilities for future enhancements of both the hardware and software.

  5. NASA Laboratory telerobotic manipulator control system architecture

    NASA Technical Reports Server (NTRS)

    Rowe, J. C.; Butler, P. L.; Glassell, R. L.; Herndon, J. N.

    1991-01-01

    In support of the National Aeronautics and Space Administration (NASA) goals to increase the utilization of dexterous robotic systems in space, the Oak Ridge National Laboratory (ORNL) has developed the Laboratory Telerobotic Manipulator (LTM) system. It is a dexterous, dual-arm, force reflecting teleoperator system with robotic features for NASA ground-based research. This paper describes the overall control system architecture, including both the hardware and software. The control system is a distributed, modular, and hierarchical design with flexible expansion capabilities for future enhancements of both the hardware and software.

  6. Recommended procedures for performance testing of radiobioassay laboratories: Volume 1, Quality assurance. [Contains Glossary

    SciTech Connect

    Fenrick, H.W.; MacLellan, J.A.

    1988-11-01

    Draft American National Standards Institute (ANSI) Standard N13.30 (Performance Criteria for Radiobioassay) was developed in response to a concern expressed by the US Department of Energy and US Nuclear Regulatory Commission to help ensure that bioassay laboratories provide accurate and consistent results. The draft standard specifies the criteria for defining the procedures necessary to establish a bioassay performance-testing laboratory and program. The testing laboratory will conduct tests to evaluate the performance of service laboratories. Pacific Northwest Laboratory helped define responsibilities and develop procedures as part of an effort to evaluate the draft ANSI N13.30 performance criteria for quality assurance at bioassay laboratories. This report recommends elements of quality assurance and quality control responsibilities for the bioassay performance-testing laboratory program, including the qualification and performance of personnel and the calibration, certification, and performance of equipment. The data base and recommended records system for documenting radiobioassay performance at the service laboratories are also presented. 15 refs.

  7. Laboratory and field analysis of factors affecting quality of leachate from coal storage piles

    Microsoft Academic Search

    E. C. Davis; W. J. Jr. Boegly; T. Tamura

    1981-01-01

    It is the purpose of this research to investigate the potential environmental problems associated with the runnoff from coal storage facilities and to suggest methods of circumventing the acidic leachate. Specifically, controlled laboratory and field-scale experiments have been carried out which identify and investigate various factors believed to be influential in determining leachate quality. These factors, including coal type (high

  8. Quality control of moxalactam susceptibility disks.

    PubMed Central

    Barry, A L; Preston, D A; Jones, R N; Gavan, T L; Thornsberry, C

    1983-01-01

    In vitro evaluation of two types of moxalactam disks revealed significant performance differences when Staphylococcus aureus was being tested. The differences were traced to the amount of decarboxylated moxalactam present in the disks. The decarboxylated analog was much more active than the parent compound against S. aureus, not active against Pseudomonas aeruginosa, and approximately as active as the parent compound against Escherichia coli. A nine-laboratory coordinated study was performed to establish quality control parameters for 30-micrograms moxalactam disks. Problems with the establishment of interpretive standards for moxalactam disk tests were evaluated in the light of differences between disks utilized in earlier studies and those that are now commercially available. The type of disk greatly influences standards for tests with S. aureus but has insignificant influence on testing gram-negative bacilli. PMID:6223936

  9. 21 CFR 225.58 - Laboratory controls.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...Laboratory controls. (a) The periodic assay of medicated feeds for drug components...intended potency. (b) The following assay requirements shall apply to medicated feeds...in this chapter. At least one of these assays shall be performed on the first...

  10. Mars Science Laboratory thermal control architecture

    NASA Technical Reports Server (NTRS)

    Bhandari, Pradeep; Birur, Gajanana; Pauken, Michael; Paris, Anthony; Novak, Keith; Prina, Mauro; Ramirez, Brenda; Bame, David

    2005-01-01

    The Mars Science Laboratory (MSL) mission to land a large rover on Mars is being planned for launch in 2009. This paper will describe the basic architecture of the thermal control system, the challenges and the methods used to overcome them by the use of an innovative architecture to maximize the use of heritage from past projects while meeting the requirements for the design.

  11. LAWRENCE BERKELEY NATIONAL LABORATORY CONTROLLER'S OFFICE

    E-print Network

    LAWRENCE BERKELEY NATIONAL LABORATORY CONTROLLER'S OFFICE Accounts Payable Mail Stop: 90J0109 Voice such payments if: The recipient has not provided a taxpayer identification number (TIN) in the required manner (form W-9). The taxpayer identification number provided does not match the IRS TIN matching database

  12. Quality factor control for micromechanical resonators

    Microsoft Academic Search

    C. T.-C. Nguyen; R. T. Howe

    1992-01-01

    The implementation of very high Q microelectromechanical filters, constructed of spring-coupled or parallel resonators, requires strict control over the quality factor of the constituent resonators. This report details electrostatic feedback techniques which allow precise control of the quality factor of a micromechanical resonator device, independent of the ambient operating pressure of the micromechanical system. Theoretical formulas governing Q-control are derived

  13. Quality Engineering: Control, Design and Optimization

    Microsoft Academic Search

    Qianmei Feng; Kailash C. Kapur

    This chapter reviews the present status and new trends in quality engineering for control, design, and optimization of product\\u000a and manufacturing processes as well as other processes\\/systems. Reviews of quality management strategies and programs are\\u000a presented including principle-centered quality improvement, quality function deployment, Six Sigma process improvement, and\\u000a Design for Six Sigma. Techniques for off-line quality engineering are presented with

  14. Idaho National Laboratory (INL) Sitewide Institutional Controls Plan

    SciTech Connect

    W. L. Jolley

    2006-07-27

    On November 9, 2002, the U.S. Environmental Protection Agency (EPA), the U.S. Department of Energy (DOE), and the Idaho Department of Environmental Quality approved the Record of Decision Experimental Breeder Reactor-I/Boiling Water Reactor Experiment Area and Miscellaneous Sites, which requires a Sitewide Institutional Controls Plan for the then Idaho National Engineering and Environmental Laboratory (now known as the Idaho National Laboratory). This document, first issued in June 2004, fulfilled that requirement. The revision is needed to provide an update as remedial actions are completed and new areas of concern are found. This Sitewide Institutional Controls Plan is based on guidance in the May 3, 1999, EPA Region 10 Final Policy on the Use of Institutional Controls at Federal Facilities; the September 29, 2000, EPA guidance Institutional Controls: A Site Manager's Guide to Identifying, Evaluating, and Selecting Institutional Controls at Superfund and RCRA Corrective Action Cleanups; and the April 9, 2003, DOE Policy 454.1, "Use of Institutional Controls." These policies establish measures that ensure short- and long-term effectiveness of institutional controls that protect human health and the environment at federal facility sites undergoing remedial action pursuant to the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) and/or corrective action pursuant to the Resource Conservation and Recovery Act (RCRA). The site-specific institutional controls currently in place at the Idaho National Laboratory are documented in this Sitewide Institutional Controls Plan. This plan is being updated, along with the Idaho National Engineering and Environmental Laboratory Comprehensive Facilities and Land Use Plan, to reflect the progress of remedial activities and changes in CERCLA sites.

  15. Quality Assurance/Quality Control (QA/QC) Summary for Year 1 of the California Coast Survey Quality Assurance/Quality Control (QA/QC)

    E-print Network

    APPENDIX 1 Quality Assurance/Quality Control (QA/QC) Summary for Year 1 of the California Coast Survey 1 APPENDIX 1 Quality Assurance/Quality Control (QA/QC) Summary for Year 1 of the California Coast Quality Assurance/Quality Control (QA/QC) Summary for Year 1 of the California Coast Survey 2 The data

  16. Information quality-control model

    NASA Technical Reports Server (NTRS)

    Vincent, D. A.

    1971-01-01

    Model serves as graphic tool for estimating complete product objectives from limited input information, and is applied to cost estimations, product-quality evaluations, and effectiveness measurements for manpower resources allocation. Six product quality levels are defined.

  17. Laboratory medicine in Ontario: its downsizing and the consequences on quality.

    PubMed

    Richardson, H

    1999-12-01

    Health care in Ontario consumes 35% of provincial government annual revenues. Fiscal constraint mandates restructuring of health services to maintain a fully, publicly-funded universally-accessible health system that is patient-focussed and health-outcome driven. Acute-care hospital restructuring under the authority of the Health Services Restructuring Commission and primary health-care reform characterise present government initiatives. Laboratory medicine services at about Can $1 billion annually account for about 5% of health expenditure. A Laboratory Services Restructuring Secretariat created by the Ministry of Health in 1995 has planned regionally-based integrated laboratory services systems bringing together public and private providers, designed a province-wide laboratory information system, developed a quality management program, reviewed the human resource needs for laboratory physicians, scientists and technologists, and recommended that the legislation be rewritten so as to be enabling - not controlling. Meanwhile both hospital and private laboratories have closed, leaving 296 in 1998 compared to 394 in 1991. Laboratory physician numbers at 39 per million population falls far short of the recommended target of 52 and many are within 10 years of retirement. Renewal of laboratory physicians and scientists to meet the shortfall is not occurring. The numbers of registered laboratory technologists has fallen by 6. 8% over 2 years. Consolidation and downsizing of laboratories with the formation of core laboratories has resulted in multi-discipline and cross discipline tasking of specialist technologists. Senior and middle level management technologists have been declared redundant. As a consequence, quality control practices have been hard hit. Plans to address these deficiencies through regional integration and sharing of resources remain to be implemented. PMID:10585512

  18. Laboratory Quality Systems VTMI 629/SCSC 629 | Summer 2014 (10-week)

    E-print Network

    Laboratory Quality Systems VTMI 629/SCSC 629 | Summer 2014 (10-week) Drs. Dai & Herrman http@otsc.tamu.edu Course Description: Quality systems and method development used within a laboratory; ensuring laboratory standards; regulatory requirements for laboratory operation; bio-security precautions; laboratory

  19. Quality control education in the community college

    NASA Technical Reports Server (NTRS)

    Greene, J. Griffen; Wilson, Steve

    1966-01-01

    This paper describes the Quality Control Program at Daytona Beach Junior College, including course descriptions. The program in quality control required communication between the college and the American Society for Quality Control (ASQC). The college has machinery established for certification of the learning process, and the society has the source of teachers who are competent in the technical field and who are the employers of the educational products. The associate degree for quality control does not have a fixed program, which can serve all needs, any more than all engineering degrees have identical programs. The main ideas which would be common to all quality control programs are the concept of economic control of a repetitive process and the concept of developing individual potentialities into individuals who are needed and productive.

  20. 30 CFR 28.31 - Quality control plans; contents.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 2012-07-01 2012-07-01 false Quality control plans; contents. 28.31 Section 28...PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.31 Quality control plans; contents. (a) Each quality...

  1. 30 CFR 28.31 - Quality control plans; contents.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 2013-07-01 2013-07-01 false Quality control plans; contents. 28.31 Section 28...PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.31 Quality control plans; contents. (a) Each quality...

  2. 30 CFR 28.31 - Quality control plans; contents.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 2014-07-01 2014-07-01 false Quality control plans; contents. 28.31 Section 28...PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.31 Quality control plans; contents. (a) Each quality...

  3. Gradient algorithm applied to laboratory quantum control

    SciTech Connect

    Roslund, Jonathan; Rabitz, Herschel [Department of Chemistry, Princeton University, Princeton, New Jersey 08544 (United States)

    2009-05-15

    The exploration of a quantum control landscape, which is the physical observable as a function of the control variables, is fundamental for understanding the ability to perform observable optimization in the laboratory. For high control variable dimensions, trajectory-based methods provide a means for performing such systematic explorations by exploiting the measured gradient of the observable with respect to the control variables. This paper presents a practical, robust, easily implemented statistical method for obtaining the gradient on a general quantum control landscape in the presence of noise. In order to demonstrate the method's utility, the experimentally measured gradient is utilized as input in steepest-ascent trajectories on the landscapes of three model quantum control problems: spectrally filtered and integrated second harmonic generation as well as excitation of atomic rubidium. The gradient algorithm achieves efficiency gains of up to approximately three times that of the standard genetic algorithm and, as such, is a promising tool for meeting quantum control optimization goals as well as landscape analyses. The landscape trajectories directed by the gradient should aid in the continued investigation and understanding of controlled quantum phenomena.

  4. [Quality assurance in radiology: quality control of radiographic cassettes].

    PubMed

    Ferretti, P P; Sarti, M; Messori, P; Boni, L; Seligardi, P; Tassoni, D; Cattini, V; Piccagli, V; Barani, A; Bianchi, C; Borasi, G; Troiso, A; Soliani Raschini, C

    1996-09-01

    A "quality team" in radiology, whose members are the authors of this paper, has implemented a quality control program to test the cassettes with intensifying screen systems used in radiology departments. 149 systems-124 of them for general purpose radiology and 25 for mammography-were submitted to the following tests: visual inspection of radiographic cassettes and intensifying screens, screen-film contact, intensifying screen cleanliness and relative sensitivity of the intensifying screens. The results of each type of test are reported in detail in the paper, on a 3-point scale: good, sufficient and poor. The overall results of the quality control tests show 78% of general purpose radiology cassettes to qualify as good (69%) or sufficient (9%), while 22% were of poor quality. 88% of the mammographic cassettes qualified as good (76%) or sufficient (12%), while 12% were of poor quality. All tests were easy to perform and required limited resources. The necessary procedures to keep quality high over time are also reported. To conclude, the results obtained with our quality control program could be used as an effective tool to address and plan the turnover of the cassettes with intensifying screens which are usually used in diagnostic radiology practice. PMID:8975314

  5. Controlled Space Physics Experiments using Laboratory Magnetospheres

    NASA Astrophysics Data System (ADS)

    Mauel, M. E.; Kesner, J.; Garnier, D.

    2013-12-01

    Modern society's reliance on space-based platforms for a variety of economic and geopolitical purposes makes understanding the physics of the magnetosphere and "space weather'' one of the most important applications of plasma science. During the past decade, results from the CTX and LDX laboratory magnetospheres and from the RT-1 device at University of Tokyo, we have developed techniques to explore space physics using controlled experiments in laboratory magnetospheres. This presentation briefly reviews observations from the laboratory magnetospheres at Columbia University and MIT, including adiabatic drift-resonant transport, low-frequency MHD turbulence, and the formation of high-beta plasmas with profiles similar to Earth's inner magnetosphere. First principle validation of ``whole plasma'' space weather models have been completed in relevant magnetic geometry, including the spectrum and dynamics of turbulence successfully modeled with nonlinear bounce-averaged gyrokinetic simulations. Plans to explore Alfvénic dynamics and whistler wave trapping are discussed through the achievement of higher-density plasmas using radio-frequency heating. Photographs of the laboratory magnetospheres located at MIT (top) and Columbia University (bottom).

  6. [Pharmaceutical product quality control and good manufacturing practices].

    PubMed

    Hiyama, Yukio

    2010-01-01

    This report describes the roles of Good Manufacturing Practices (GMP) in pharmaceutical product quality control. There are three keys to pharmaceutical product quality control. They are specifications, thorough product characterization during development, and adherence to GMP as the ICH Q6A guideline on specifications provides the most important principles in its background section. Impacts of the revised Pharmaceutical Affairs Law (rPAL) which became effective in 2005 on product quality control are discussed. Progress of ICH discussion for Pharmaceutical Development (Q8), Quality Risk Management (Q9) and Pharmaceutical Quality System (Q10) are reviewed. In order to reconstruct GMP guidelines and GMP inspection system in the regulatory agencies under the new paradigm by rPAL and the ICH, a series of Health Science studies were conducted. For GMP guidelines, product GMP guideline, technology transfer guideline, laboratory control guideline and change control system guideline were written. For the GMP inspection system, inspection check list, inspection memo and inspection scenario were proposed also by the Health Science study groups. Because pharmaceutical products and their raw materials are manufactured and distributed internationally, collaborations with other national authorities are highly desired. In order to enhance the international collaborations, consistent establishment of GMP inspection quality system throughout Japan will be essential. PMID:21381389

  7. QUALITY CONTROL FOR RESEARCH STUDIES: A CRITICAL PART OF THE QUALITY SYSTEM AT THE U. S. EPA

    EPA Science Inventory

    QUALITY CONTROL FOR RESEARCH STUDIES: A CRITICAL PART OF THE QUALITY SYSTEM AT THE U.S. EPA Mette C.J. Schladweiler, Scientist, and Thomas J. Hughes, QA and Records Manager, Experimental Toxicology Division (ETD), National Health and Environmental Effects Research Laboratory (NHE...

  8. Quality Control in Coastal GIS

    Microsoft Academic Search

    Darius Bartlett; Eleanor Bruce

    \\u000a The field of coastal geographical information systems (GIS) has matured, in parallel with more general advances in spatial\\u000a information technologies, to a stage where there is now a growing urgency to examine the issue of quality regarding developed\\u000a applications. Although quality in GIS has been recognised as an important issue for almost two decades (Chrisman, 1982; Blakemore,\\u000a 1983; Burrough, 1986;

  9. DEVELOPMENT OF AN ENVIRONMENTAL QUALITY TEACHING LABORATORY AND SUPPLEMENTARY EXPERIENTIAL LEARNING ACTIVITIES

    Technology Transfer Automated Retrieval System (TEKTRAN)

    In an effort to improve the ability of agriculturally and environmentally oriented graduates to work in interdisciplinary teams to solve problems, an environmental quality teaching laboratory was developed. In this laboratory, virtual, field, and laboratory experiences provide the experiential and ...

  10. Systems & Control LaboratoryKanazawa University Kanazawa University

    E-print Network

    16 1 1 Systems & Control LaboratoryKanazawa University Kanazawa University 0223022202 2Systems & Control LaboratoryKanazawa University Kanazawa University · 1.1: · · ( [16] Doyle , 89 ) time time · 1.2: F-16 Aircraft 3Systems & Control LaboratoryKanazawa University Kanazawa

  11. Minimum Cost Quality Control Tests

    Microsoft Academic Search

    H. Allan Knappenberger; A. H. E. Grandage

    1969-01-01

    An expected cost model of a process whose mean is controlled by an X chart is developed. A two-stage numerical procedure is used to calculate the sample size, the number of units produced between samples, and the control limits of optimal control charts. Optimal plans are tabulated for three values of the a priori distribution parameter and three values of

  12. Automobile quality choice under pollution control regulation

    Microsoft Academic Search

    Ida Ferrara

    2007-01-01

    In this paper, we develop a modified quality choice model to study the effects of various mobile-source air pollution control\\u000a regulations. We have a single producer that supplies a fixed number of car types (two) but faces a spectrum of consumers differing\\u000a in their valuation of car quality. The car manufacturer chooses the quality levels of the two car types

  13. Cell culture quality control by rapid isoenzymatic characterization

    Microsoft Academic Search

    David M. Halton; Ward D. Peterson; Bharati Hukku

    1983-01-01

    Summary  Procedures that involve cell cultures require careful quality control to avoid inter- and intraspecies contamination. We have\\u000a developed and electrophoresis technique that can be used routinely in cell culture laboratories to monitor cell line integrity.\\u000a The method involves the isoenzymatic separation of nine polymorphic enzymes, three of which can be used for cell line species\\u000a determinations and seven of which

  14. ER quality control can lead to retrograde transport from the ER lumen to the cytosol and the nucleoplasm in plants

    E-print Network

    ER quality control can lead to retrograde transport from the ER lumen to the cytosol-mail fbrandizzi@brookes.ac.uk). y Both laboratories contributed equally. Summary Quality control in the secretory by proteasome inhibitors. Keywords: GFP, ERAD, quality control, secretory pathway. Introduction As nascent

  15. Quality or Control? Management in Higher Education

    ERIC Educational Resources Information Center

    Milliken, John; Colohan, Gerry

    2004-01-01

    Over the past fifteen years the rationale, organisational infrastructure and delivery of social policy in Britain have undergone radical transformation. Whereas efficiency was the key word of the 1980s, quality was the touchstone of the 1990s and quality control with accountability has become the management philosophy of the new millennium.…

  16. Striving for Quality Control in Distance Education.

    ERIC Educational Resources Information Center

    Leh, Amy S. C.; Jobin, Andrianna

    2002-01-01

    Discussion of the benefits and drawbacks of distance education and online instruction in higher education focuses on quality control. Topics include quality of product, of learning, and of technology; student prerequisites; instructional design; faculty support systems; and program design, including professional development versus academic degree…

  17. Exploratory data analysis for preemptive quality control

    E-print Network

    Karamanc?, Kaan

    2009-01-01

    In this thesis, I proposed and implemented a methodology to perform preemptive quality control on low-tech industrial processes with abundant process data. This involves a 4 stage process which includes understanding the ...

  18. Quality control systems in cardiac aging.

    PubMed

    Quarles, Ellen K; Dai, Dao-Fu; Tocchi, Autumn; Basisty, Nathan; Gitari, Lemuel; Rabinovitch, Peter S

    2015-09-01

    Cardiac aging is an intrinsic process that results in impaired cardiac function, along with cellular and molecular changes. These degenerative changes are intimately associated with quality control mechanisms. This review provides a general overview of the clinical and cellular changes which manifest in cardiac aging, and the quality control mechanisms involved in maintaining homeostasis and retarding aging. These mechanisms include autophagy, ubiquitin-mediated turnover, apoptosis, mitochondrial quality control and cardiac matrix homeostasis. Finally, we discuss aging interventions that have been observed to impact cardiac health outcomes. These include caloric restriction, rapamycin, resveratrol, GDF11, mitochondrial antioxidants and cardiolipin-targeted therapeutics. A greater understanding of the quality control mechanisms that promote cardiac homeostasis will help to understand the benefits of these interventions, and hopefully lead to further improved therapeutic modalities. PMID:25702865

  19. CLAY LINER CONSTRUCTION AND QUALITY CONTROL

    EPA Science Inventory

    Soil handling and liner construction practices at hazardous waste management facilities are documented. Soil characterizations, processing techniques, construction methods, and quality control of constructed liners are reviewed and compared. Results indicate widely different test...

  20. Quality Control for Spirometry in Preschool Children with and without Lung Disease

    Microsoft Academic Search

    Paul Aurora; Janet Stocks; Cara Oliver; Clare Saunders; Rosemary Castle; Greg Chaziparasidis; Andrew Bush

    2004-01-01

    The reliability of spirometry is dependent on strict quality control. We examined whether quality control criteria recommended for adults could be applied to children aged 2-5 years. Forty-two chil- dren with cystic fibrosis and 37 healthy children attempted spirome- try during their first visit to our laboratory. Whereas 59 children (75%) were able to produce a technically satisfactory forced expira-

  1. Quality Control under Markovian Deterioration

    Microsoft Academic Search

    Sheldon M. Ross

    1971-01-01

    We suppose that a production process may be in any one of a countable number of states and that the quality of the item produced is a function of this underlying state. It is also supposed that the state of the process at time t is not known and only becomes known when an item is sampled. We suppose that

  2. Dietary Supplement Laboratory Quality Assurance Program: The First Five Exercises

    PubMed Central

    Phillips, Melissa M.; Rimmer, Catherine A.; Wood, Laura J.; Lippa, Katrice A.; Sharpless, Katherine E.; Duewer, David L.; Sander, Lane C.; Betz, Joseph M.

    2011-01-01

    The National Institute of Standards and Technology (NIST) has established a Dietary Supplement Laboratory Quality Assurance Program (DSQAP) in collaboration with the National Institutes of Health Office of Dietary Supplements. Program participants measure concentrations of active and/or marker compounds as well as nutritional and toxic elements in food and dietary supplements distributed by NIST. Data are compiled at NIST, where they are analyzed for accuracy relative to reference values and concordance among the participants. Performance reports and certificates of completion are provided to participants, which can be used to demonstrate compliance with current Good Manufacturing Practices as promulgated by the U.S. Food and Drug Administration. The DSQAP has conducted five exercises to date, with total participation including more than 75 different laboratories and many more individual analysts. PMID:21797008

  3. Quality control in the endoplasmic reticulum

    Microsoft Academic Search

    Lars Ellgaard; Ari Helenius

    2003-01-01

    The endoplasmic reticulum (ER) has a quality-control system for 'proof-reading' newly synthesized proteins, so that only native conformers reach their final destinations. Non-native conformers and incompletely assembled oligomers are retained, and, if misfolded persistently, they are degraded. As a large fraction of ER-synthesized proteins fail to fold and mature properly, ER quality control is important for the fidelity of cellular

  4. 46 CFR 164.019-13 - Production quality control requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...and the accepted quality control and oversight...manufacturer's established quality control program...discontinuity in the manufacturing process (such as...the production quality control requirements...the same type of defect or;...

  5. 46 CFR 164.019-13 - Production quality control requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...this part, and the accepted quality control and oversight procedures...manufacturer's established quality control program and provide...component manufacturer (or supplier), by referring to the records...and all of the production quality control requirements....

  6. 46 CFR 164.019-13 - Production quality control requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...this part, and the accepted quality control and oversight procedures...manufacturer's established quality control program and provide...component manufacturer (or supplier), by referring to the records...and all of the production quality control requirements....

  7. 46 CFR 164.019-13 - Production quality control requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...this part, and the accepted quality control and oversight procedures...manufacturer's established quality control program and provide...component manufacturer (or supplier), by referring to the records...and all of the production quality control requirements....

  8. 46 CFR 164.019-13 - Production quality control requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...this part, and the accepted quality control and oversight procedures...manufacturer's established quality control program and provide...component manufacturer (or supplier), by referring to the records...and all of the production quality control requirements....

  9. 42 CFR 84.41 - Quality control plans; contents.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...41 Quality control plans; contents. (a) Each quality control plan shall contain provisions...calibration of measuring and test equipment; (4...material to include incoming inspection; (5) Lot identification...in the quality control plan shall include a...

  10. 42 CFR 84.40 - Quality control plans; filing requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 2010-10-01 false Quality control plans; filing requirements...OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL...RESPIRATORY PROTECTIVE DEVICES Quality Control § 84.40 Quality control plans; filing...

  11. 42 CFR 84.256 - Quality control requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 2010-10-01 false Quality control requirements. 84...OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL...Respirators § 84.256 Quality control requirements. ...254, and 84.255, the quality control requirements...

  12. Quality control of automated cell counters.

    PubMed

    Cembrowski, George S; Clarke, Gwen

    2015-03-01

    The hematology analyzers of today provide more reproducible analyses compared with those of a few decades ago, necessitating an evolution in hematology quality practices. The improved performance allows use of simple quality control rules. This improved performance also renders the repeat analysis of critical value specimens non value added. Some of the patient averaging techniques have become outmoded and need to be replaced by less complicated calculations but with truncation of predictable outlying populations. The ready availability of comparative peer quality control values helps to improve analyzer precision and accuracy, and simplifies instrument validation and calibration. PMID:25676372

  13. Network-based production quality control

    NASA Astrophysics Data System (ADS)

    Kwon, Yongjin; Tseng, Bill; Chiou, Richard

    2007-09-01

    This study investigates the feasibility of remote quality control using a host of advanced automation equipment with Internet accessibility. Recent emphasis on product quality and reduction of waste stems from the dynamic, globalized and customer-driven market, which brings opportunities and threats to companies, depending on the response speed and production strategies. The current trends in industry also include a wide spread of distributed manufacturing systems, where design, production, and management facilities are geographically dispersed. This situation mandates not only the accessibility to remotely located production equipment for monitoring and control, but efficient means of responding to changing environment to counter process variations and diverse customer demands. To compete under such an environment, companies are striving to achieve 100%, sensor-based, automated inspection for zero-defect manufacturing. In this study, the Internet-based quality control scheme is referred to as "E-Quality for Manufacturing" or "EQM" for short. By its definition, EQM refers to a holistic approach to design and to embed efficient quality control functions in the context of network integrated manufacturing systems. Such system let designers located far away from the production facility to monitor, control and adjust the quality inspection processes as production design evolves.

  14. Description of the Spacecraft Control Laboratory Experiment (SCOLE) facility

    NASA Technical Reports Server (NTRS)

    Williams, Jeffrey P.; Rallo, Rosemary A.

    1987-01-01

    A laboratory facility for the study of control laws for large flexible spacecraft is described. The facility fulfills the requirements of the Spacecraft Control Laboratory Experiment (SCOLE) design challenge for laboratory experiments, which will allow slew maneuvers and pointing operations. The structural apparatus is described in detail sufficient for modelling purposes. The sensor and actuator types and characteristics are described so that identification and control algorithms may be designed. The control implementation computer and real-time subroutines are also described.

  15. The quality of sputum smear microscopy in public-private mix directly observed treatment laboratories in West Amhara region, Ethiopia.

    PubMed

    Manalebh, Almaw; Demissie, Meaza; Mekonnen, Daniel; Abera, Bayeh

    2015-01-01

    Ethiopia adopted Public-Private Mix Directly Observed Treatment Short Course Chemotherapy (PPM-DOTS) strategy for tuberculosis (TB) control program. Quality of sputum smear microscopy has paramount importance for tuberculosis control program in resource-poor countries like Ethiopia. A cross-sectional study was conducted to assess the quality of sputum smear microscopy in 37 Public-Private Mix laboratories in West Amhara, Ethiopia. The three external quality assessment methods (onsite evaluation, panel testing and blind rechecking) were employed. Onsite assessment revealed that 67.6% of PPM-DOTS laboratories were below the standard physical space (5 X 6) m2. The average monthly workload per laboratory technician was 19.5 (SD±2.9) slides with 12.8% positivity rate. The quality of Acid Fast Bacilli (AFB) staining reagents was sub-standard. The overall agreement for blind rechecking of 1,123 AFB slides was 99.4% (Kappa = 0.97). Reading of 370 AFB panel slides showed 3.5% false reading (Kappa = 0.92). Moreover, the consistency of reading scanty bacilli slides was lower (93%) compared to 1+, 2+ and 3+ bacilli. Based on blind rechecking and panel testing results, PPM-DOTS site laboratories showed good agreement with the reference laboratory. Physical space and qualities of AFB reagents would be areas of intervention to sustain the quality of sputum smear microscopy. Therefore, regular external quality assessment and provision of basic laboratory supplies for TB diagnosis would be the way forward to improve the quality of sputum smear microscopy services in PPM-DOTS laboratories. PMID:25849516

  16. The Quality of Sputum Smear Microscopy in Public-Private Mix Directly Observed Treatment Laboratories in West Amhara Region, Ethiopia

    PubMed Central

    Manalebh, Almaw; Demissie, Meaza; Mekonnen, Daniel; Abera, Bayeh

    2015-01-01

    Ethiopia adopted Public-Private Mix Directly Observed Treatment Short Course Chemotherapy (PPM-DOTS) strategy for tuberculosis (TB) control program. Quality of sputum smear microscopy has paramount importance for tuberculosis control program in resource-poor countries like Ethiopia. A cross-sectional study was conducted to assess the quality of sputum smear microscopy in 37 Public-Private Mix laboratories in West Amhara, Ethiopia. The three external quality assessment methods (onsite evaluation, panel testing and blind rechecking) were employed. Onsite assessment revealed that 67.6% of PPM-DOTS laboratories were below the standard physical space (5 X 6) m2. The average monthly workload per laboratory technician was 19.5 (SD±2.9) slides with 12.8% positivity rate. The quality of Acid Fast Bacilli (AFB) staining reagents was sub-standard. The overall agreement for blind rechecking of 1,123 AFB slides was 99.4% (Kappa = 0.97). Reading of 370 AFB panel slides showed 3.5% false reading (Kappa = 0.92). Moreover, the consistency of reading scanty bacilli slides was lower (93%) compared to 1+, 2+ and 3+ bacilli. Based on blind rechecking and panel testing results, PPM-DOTS site laboratories showed good agreement with the reference laboratory. Physical space and qualities of AFB reagents would be areas of intervention to sustain the quality of sputum smear microscopy. Therefore, regular external quality assessment and provision of basic laboratory supplies for TB diagnosis would be the way forward to improve the quality of sputum smear microscopy services in PPM-DOTS laboratories. PMID:25849516

  17. Maintaining data quality in an environmental testing laboratory

    SciTech Connect

    Cohen, Roy J.

    2001-03-05

    In today's competitive and highly litigious world, it is critical that any laboratory generating data for the environmental and allied industries have a world-class Quality Assurance Program. This Plan must conform to the requirements of every agency and client with whom the lab does business. The goal of such a program is data defensibility; i.e., data validity. Data (usually qualitative analyte [compound or element] identifications and quantitative numerical results) are the end results of nearly all analytical laboratory processes, and the source of revenue. Clients pay for results. The clients expect the results to be accurate, precise, and repeatable. If their data has to go to court, the laboratory will be called upon to defend the accuracy and precision of their work. Without a strong QA program, this will be impossible. The potential implications and repercussions of non-defensible lab data are far-reaching and very costly in terms of loss of future revenues and in legal judgments.

  18. Principles of Water Quality Control.

    ERIC Educational Resources Information Center

    Tebbutt, T. H. Y.

    This book is designed as a text for undergraduate civil engineering courses and as preliminary reading for postgraduate courses in public health engineering and water resources technology. It is also intended to be of value to workers already in the field and to students preparing for the examinations of the Institute of Water Pollution Control

  19. Quality control by a mobile molecular workshop: quality versus quantity

    E-print Network

    Ajeet K. Sharma; Debashish Chowdhury

    2010-09-27

    Ribosome is a molecular machine that moves on a mRNA track while, simultaneously, polymerizing a protein using the mRNA also as the corresponding template. We define, and analytically calculate, two different measures of the efficiency of this machine. However, we arugue that its performance is evaluated better in terms of the translational fidelity and the speed with which it polymerizes a protein. We define both these quantities and calculate these analytically. Fidelity is a measure of the quality of the products while the total quantity of products synthesized in a given interval depends on the speed of polymerization. We show that for synthesizing a large quantity of proteins, it is not necessary to sacrifice the quality. We also explore the effects of the quality control mechanism on the strength of mechano-chemical coupling. We suggest experiments for testing some of the ideas presented here.

  20. QUALITY ASSURANCE AND QUALITY CONTROL FOR DRINKING WATER LABORATORIES

    EPA Science Inventory

    Soon after the US Environmental Protection Agency (USEPA) was formed in 1972, agency administrators realized that in order to make appropriate decisions for environmental regulation, they must be assured that data being generated by the agency and the 50 states were valid and leg...

  1. Engineering Software under Statistical Quality Control

    Microsoft Academic Search

    Richard H. Cobb; Harlan D. Mills

    1990-01-01

    Eight common misconceptions of software quality are examined and refuted. The concept of cleanroom engineering of software is introduced. Cleanroom engineering achieves intellectual control by applying rigorous, mathematics-based engineering practices, establishes an errors-are-unacceptable attitude and a team responsibility for quality, delegates development and testing responsibilities to separate teams, and certifies the software's mean time to failure through the application of

  2. Argonne National Laboratory Internal Appraisal Program environment, safety, health\\/quality assurance oversight

    Microsoft Academic Search

    G. L. Winner; Y. S. Siegfried; S. P. Forst; M. J. Meshenberg

    1995-01-01

    Argonne National Laboratory`s Internal Appraisal Program has developed a quality assurance team member training program. This program has been developed to provide training to non-quality assurance professionals. Upon successful completion of this training and approval of the Internal Appraisal Program Manager, these personnel are considered qualified to assist in the conduct of quality assurance assessments. The training program has been

  3. Addendum 1 -Procedures for data quality control Data Quality Control Procedures

    E-print Network

    Newman, Michael C.

    38 Addendum 1 - Procedures for data quality control Data Quality Control Procedures John M. Hoenig make a change to a database, enter your name, the date, and a description & justification of the change checked 3)Every database should have embedded in it an explanation of every column heading, every symbol

  4. Post-translational Modification and Quality Control

    PubMed Central

    Wang, Xuejun; Pattison, J. Scott; Su, Huabo

    2013-01-01

    Protein quality control (PQC) functions to minimize the level and toxicity of misfolded proteins in the cell. PQC is performed by intricate collaboration among chaperones and target protein degradation. The latter is carried out primarily by the ubiquitin-proteasome system and perhaps autophagy. Terminally misfolded proteins that are not timely removed tend to form aggregates. Their clearance requires macroautophagy. Macroautophagy serves in intracellular quality control also by selectively segregating defective organelles (e.g., mitochondria) and targeting them for degradation by the lysosome. Inadequate PQC is observed in a large subset of failing human hearts with a variety of etiologies and its pathogenic role has been experimentally demonstrated. Multiple post-translational modifications (PTMs) can occur to substrate proteins and/or PQC machineries, promoting or hindering the removal of the misfolded proteins. This article highlights recent advances in PTMs-mediated regulation of intracellular quality control mechanisms and its known involvement in cardiac pathology. PMID:23329792

  5. Safety in the Chemical Laboratory: Fire Safety and Fire Control in the Chemistry Laboratory.

    ERIC Educational Resources Information Center

    Wilbraham, A. C.

    1979-01-01

    Discusses fire safety and fire control in the chemistry laboratory. The combustion process, extinguishing equipment, extinguisher maintenance and location, and fire safety and practices are included. (HM)

  6. Quality Assurance/Quality Control (QA/QC) Summary for the California Rivers and Streams Study

    E-print Network

    APPENDIX 1 Quality Assurance/Quality Control (QA/QC) Summary for the California Rivers and Streams (Bonnema 2011). In general, data quality is demonstrated through analysis of the following quality control may arise so that corrective actions can be implemented. Quality control samples prepared and analyzed

  7. QUALITY ASSURANCE / QUALITY CONTROL MANUAL FOR THE LOWER CAPE FEAR RIVER PROGRAM

    E-print Network

    Mallin, Michael

    QUALITY ASSURANCE / QUALITY CONTROL MANUAL FOR THE LOWER CAPE FEAR RIVER PROGRAM Aquatic Ecology and Quality Control (QA/QC) procedures developed for the Lower Cape Fear River Program (LCFRP) in association Science (UNCW-CMS). The primary goal of this quality assurance/quality control plan is to provide

  8. Using analytical services at the National Water Quality Laboratory

    USGS Publications Warehouse

    Pratt, L.K.

    1994-01-01

    The National Water Quality Laboratory (NWQL) offers a variety of analytical services for the determination of constituents in samples of water, sediment, and biological material. As technology has advanced, many new methods have been introduced but not always incorporated into plans and schedules developed in the districts. The strengths and weaknesses of many different techniques are discussed and evaluated to promote a broad understanding of the services available at the NWQL. Method detection limits, precision, and costs are discussed, as well as possible applications for the methods. To aid in project planning, several tables have been developed that list the approved method for certain determination, particularly those being requested to satisfy cooperator or U.S. Environ- mental Protection Agency regulatory requirements.

  9. An Approach to Medical Errors and Patient Safety in Laboratory Services A White Paper Prepared for the Quality Institute Meeting Making the Laboratory a Partner in Patient Safety Atlanta, April 2003 Division of Laboratory Systems Centers for Disease Control and Prevention

    Microsoft Academic Search

    Marc D. Silverstein

    The Institute of Medicine (IOM) reports, To Err Is Human and Crossing The Quality Chasm have focused attention on medical errors, patient safety, and the quality of care. Quality can be defined and measured and improved. Examples of quality improvement programs include the accreditation programs of the Joint Commission for Accreditation of Health Care Organizations, the Centers for Medicaid and

  10. Quality control in the secretory assembly line.

    PubMed Central

    Helenius, A

    2001-01-01

    As a rule, only proteins that have reached a native, folded and assembled structure are transported to their target organelles and compartments within the cell. In the secretory pathway of eukaryotic cells, this type of sorting is particularly important. A variety of molecular mechanisms are involved that distinguish between folded and unfolded proteins, modulate their intracellular transport, and induce degradation if they fail to fold. This phenomenon, called quality control, occurs at several levels and involves different types of folding sensors. The quality control system provides a stringent and versatile molecular sorting system that guaranties fidelity of protein expression in the secretory pathway. PMID:11260794

  11. HPLC for quality control of polyimides

    NASA Technical Reports Server (NTRS)

    Young, P. R.; Sykes, G. F.

    1979-01-01

    High Pressure Liquid Chromatography (HPLC) as a quality control tool for polyimide resins and prepregs are presented. A data base to help establish accept/reject criteria for these materials was developed. This work is intended to supplement, not replace, standard quality control tests normally conducted on incoming resins and prepregs. To help achieve these objectives, the HPLC separation of LARC-160 polyimide precursor resin was characterized. Room temperature resin aging effects were studied. Graphite reinforced composites made from fresh and aged resin were fabricated and tested to determine if changes observed by HPLC were significant.

  12. Quality Control Protocol for Confocal Systems

    PubMed Central

    Cornea, Anda

    2014-01-01

    Quantitative analysis of confocal imaging experiments require more stringent quality control of instrument function than qualitative imaging. Unfortunately, there are no standard procedures for quality control that are uniformly implemented, and, in multi user facilities experimenters rarely have access to the QC information. This paper proposes an easy and very efficient protocol that could be performed at the beginning of each day, experiment or even slide. It takes only a few minutes to assess laser stability, stage stability, channel registration in 3 dimensions and flatness of field. The information may be used either to calibrate data or, in more severe cases to request servicing the instrument. PMID:23317897

  13. [The establishment and research of ventilator quality control information system].

    PubMed

    Li, Tao; Zhang, Nan; Pu, Wei

    2013-05-01

    Ventilator quality control is an important task for the management of hospital medical equipment. Analysis the problems of hospital medical device quality control and introducing ventilator quality control information system design and technical characteristics. The application of the system can improve the efficiency of quality control, and enhance hospital medical equipment management level. PMID:24015622

  14. Quality Control and Early Diagnostics for cDNA Microarrays

    E-print Network

    Sawitzki, Günther

    Quality Control and Early Diagnostics for cDNA Microarrays by Günther Sawitzki1 We present a case in the finer issues, but these details can only be mentioned in passing. Quality Control for Microarrays it quality control. We use R for quality control of microarrays. We simplify and specialize the problem

  15. 21 CFR 111.117 - What quality control operations are required for equipment, instruments, and controls?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...2013-04-01 2013-04-01 false What quality control operations are required for equipment, instruments...Process Control System: Requirements for Quality Control § 111.117 What quality control operations are required for equipment,...

  16. 21 CFR 111.117 - What quality control operations are required for equipment, instruments, and controls?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...2012-04-01 2012-04-01 false What quality control operations are required for equipment, instruments...Process Control System: Requirements for Quality Control § 111.117 What quality control operations are required for equipment,...

  17. The consistency approach for the quality control of vaccines.

    PubMed

    Hendriksen, Coenraad; Arciniega, Juan L; Bruckner, Lukas; Chevalier, Michel; Coppens, Emmanuelle; Descamps, Johan; Duchêne, Michel; Dusek, David Michael; Halder, Marlies; Kreeftenberg, Hans; Maes, Alexandrine; Redhead, Keith; Ravetkar, Satish D; Spieser, Jean-Marc; Swam, Hanny

    2008-01-01

    Current lot release testing of conventional vaccines emphasizes quality control of the final product and is characterized by its extensive use of laboratory animals. This report, which is based on the outcome of an ECVAM (European Centre for Validation of Alternative Methods, Institute for Health and Consumer Protection, European Commission Joint Research Centre, Ispra, Italy) workshop, discusses the concept of consistency testing as an alternative approach for lot release testing. The consistency approach for the routine release of vaccines is based upon the principle that the quality of vaccines is a consequence of a quality system and of consistent production of lots with similar characteristics to those lots that have been shown to be safe and effective in humans or the target species. The report indicates why and under which circumstances this approach can be applied, the role of the different stakeholders, and the need for international harmonization. It also gives recommendations for its implementation. PMID:17892948

  18. Proficiency testing and other interactive measures to enhance analytical quality in soil and plant laboratories

    Microsoft Academic Search

    George E. Rayment; Robert O. Miller; Eman Sulaeman

    2000-01-01

    Clients are increasingly seeking enhanced accuracy and precision from soil and plant testing laboratories. Commitment to good laboratory practice is essential, but gains in analytical quality often depend upon inputs from peers through collaborative networks, proficiency programs and laboratory accreditation. Examples of laboratory networks are given, while proficiency programs receive attention with respect to scope, frequency and the statistical assessment

  19. External quality assessment of national public health laboratories in Africa, 2002–2009

    PubMed Central

    Perovic, Olga; Fensham, Vivian; McCarthy, Kerrigan; von Gottberg, Anne; de Gouveia, Linda; Poonsamy, Bhavani; Dini, Leigh; Rossouw, Jenny; Keddy, Karen; Alemu, Wondimagegnehu; Yahaya, Ali; Pierson, Antoine; Dolmazon, Virginie; Cognat, Sébastien; Ndihokubwayo, Jean Bosco

    2012-01-01

    Abstract Objective To describe findings from an external quality assessment programme involving laboratories in Africa that routinely investigate epidemic-prone diseases. Methods Beginning in 2002, the Regional Office for Africa of the World Health Organization (WHO) invited national public health laboratories and related facilities in Africa to participate in the programme. Three surveys comprising specimens and questionnaires associated with bacterial enteric diseases, bacterial meningitis, plague, tuberculosis and malaria were sent annually to test participants’ diagnostic proficiency. Identical surveys were sent to referee laboratories for quality control. Materials were prepared, packaged and shipped in accordance with standard protocols. Findings and reports were due within 30 days. Key methodological decisions and test results were categorized as acceptable or unacceptable on the basis of consensus feedback from referees, using established grading schemes. Findings Between 2002 and 2009, participation increased from 30 to 48 Member States of the WHO and from 39 to 78 laboratories. Each survey was returned by 64–93% of participants. Mean turnaround time was 25.9 days. For bacterial enteric diseases and meningitis components, bacterial identification was acceptable in 65% and 69% of challenges, respectively, but serotyping and antibiotic susceptibility testing and reporting were frequently unacceptable. Microscopy was acceptable for 73% of plague challenges. Tuberculosis microscopy was satisfactorily performed, with 87% of responses receiving acceptable scores. In the malaria component, 82% of responses received acceptable scores for species identification but only 51% of parasite quantitation scores were acceptable. Conclusion The external quality assessment programme consistently identified certain functional deficiencies requiring strengthening that were present in African public health microbiology laboratories. PMID:22461714

  20. 11. Interior view of control room in Components Test Laboratory ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. Interior view of control room in Components Test Laboratory (T-27), looking north. Photograph shows upgraded instrumentation, piping, and technological modifications installed in 1997-99 to accommodate component testing requirements for the Atlas V missile. - Air Force Plant PJKS, Systems Integration Laboratory, Components Test Laboratory, Waterton Canyon Road & Colorado Highway 121, Lakewood, Jefferson County, CO

  1. The Shanghai biobanking DNA quality control program.

    PubMed

    Ruan, Liangliang; Song, Yutong; Fan, Jinli; Ying, Hao; Gan, Rongxing

    2014-08-01

    Method validation is one of the crucial processes for a professional biobank. However, there are no routine guidelines specially designed for such studies. Therefore, in line with the need for competence in testing and calibration, the International Organization for Standardization (ISO) concept has been introduced to biobanking as a model for Quality Management Systems in this field. Accurate interpretation of the experimental data about the human genome depends on the quality of the genomic DNA. In this study, we focused on the validation of DNA quantitation by spectrophotometry, a basic bio-analytical method in molecular biology. The key factors of precision, accuracy testing, and linearity assessment are presented in assessing the method quality. Internal and external quality controls have been included as required. Our data show that the method of spectrophotometry is qualified for DNA quantitation. PMID:25093838

  2. QUALITY ASSURANCE GUIDELINES FOR LABORATORIES PERFORMING FORENSIC ANALYSIS OF CHEMICAL TERRORISM

    EPA Science Inventory

    The Scientific Working Group on Forensic Analysis of Chemical Terrorism (SWGFACT) has developed the following quality assurance guidelines to provide laboratories engaged in forensic analysis of chemical evidence associated with terrorism a framework to implement a quality assura...

  3. Quality-Assurance/Quality-Control Manual for Collection and Analysis of Water-Quality Data in the Ohio District, US Geological Survey

    USGS Publications Warehouse

    Francy, D.S.; Jones, A.L.; Myers, D.N.; Rowe, G.L., Jr.; Eberle, Michael; Sarver, K.M.

    1998-01-01

    The U.S. Geological Survey (USGS), Water Resources Division (WRD), requires that quality-assurance/quality-control (QA/QC) activities be included in any sampling and analysis program. Operational QA/QC procedures address local needs while incorporating national policies. Therefore, specific technical policies were established for all activities associated with water-quality project being done by the Ohio District. The policies described in this report provide Ohio District personnel, cooperating agencies, and others with a reference manual on QA/QC procedures that are followed in collecitng and analyzing water-quality samples and reporting water-quality information in the Ohio District. The project chief, project support staff, District Water-Quality Specialist, and District Laboratory Coordinator are all involved in planning and implementing QA/QC activities at the district level. The District Chief and other district-level managers provide oversight, and the Regional Water-Quality Specialist, Office of Water Quality (USGS headquarters), and the Branch of Quality Systems within the Office of Water Quality create national QA/QC polices and provide assistance to District personnel. In the literature, the quality of all measurement data is expressed in terms of precision, variability, bias, accuracy, completeness, representativeness, and comparability. In the Ohio District, bias and variability will be used to describe quality-control data generated from samples in the field and laboratory. Each project chief must plan for implementation and financing of QA/QC activities necessary to achieve data-quality objectives. At least 15 percent of the total project effort must be directed toward QA/QC activities. Of this total, 5-10 percent will be used for collection and analysis of quality-control samples. This is an absolute minimum, and more may be required based on project objectives. Proper techniques must be followed in the collection and processing of surface-water, ground-water, biological, precipitation, bed-sediment, bedload, suspended-sediment, and solid-phase samples. These techniques are briefly described in this report and are extensively documented. The reference documents listed in this report will be kept by the District librarian and District Water-Quality Specialist and updated regularly so that they are available to all District staff. Proper handling and documentation before, during, and after field activities are essential to ensure the integrity of the sample and to correct erroneous reporting of data results. Field sites are to be properly identified and entered into the data base before field data-collection activities begin. During field activities, field notes are to be completed and sample bottles appropriately labeled a nd stored. After field activities, all paperwork is to be completed promptly and samples transferred to the laboratory within allowable holding times. All equipment used by District personnel for the collection and processing of water-quality samples is to be properly operated, maintained, and calibrated by project personnel. This includes equipment for onsite measurement of water-quality characteristics (temperature, specific conductance, pH, dissolved oxygen, alkalinity, acidity, and turbidity) and equipment and instruments used for biological sampling. The District Water-Quality Specialist and District Laboratory Coordinator are responsible for preventive maintenance and calibration of equipment in the Ohio District laboratory. The USGS National Water Quality Laboratory in Arvada, Colo., is the primary source of analytical services for most project work done by the Ohio District. Analyses done at the Ohio District laboratory are usually those that must be completed within a few hours of sample collection. Contract laboratories or other USGS laboratories are sometimes used instead of the NWQL or the Ohio District laboratory. When a contract laboratory is used, the projec

  4. Quality Control & Design in Science Learning

    ERIC Educational Resources Information Center

    Sumrall, William J.; Schillinger, Don

    2003-01-01

    One area of science education that is, at times, neglected involves lessons on technological concepts of these principles--designing, testing, and quality control. Instead, a focus upon science concepts from a pure, and unapplied, perspective is the norm. Thus, while students may learn the equation "mass divided by volume equals density," the…

  5. Quality control for structural credit risk models

    Microsoft Academic Search

    Elena Andreou; Eric Ghysels

    2008-01-01

    Over the last four decades, a large number of structural models have been developed to estimate and price credit risk. The focus of the paper is on a neglected issue pertaining to fundamental shifts in the structural parameters governing default. We propose formal quality control procedures that allow risk managers to monitor fundamental shifts in the structural parameters of credit

  6. Acoustic resonance techniques for quality control

    SciTech Connect

    Sinha, D.N.

    1992-01-01

    Acoustic resonance based nondestructive techniques are described that can be used for both process and quality control in manufacturing. The Acoustic Resonance Spectroscopy (AS) technique is highlighted for its capability in fluid property (flow, density, viscosity, and speed of sound) monitoring. Possible applications of these noninvasive techniques for textile manufacturing are pointed out.

  7. Acoustic resonance techniques for quality control

    SciTech Connect

    Sinha, D.N.

    1992-09-01

    Acoustic resonance based nondestructive techniques are described that can be used for both process and quality control in manufacturing. The Acoustic Resonance Spectroscopy (AS) technique is highlighted for its capability in fluid property (flow, density, viscosity, and speed of sound) monitoring. Possible applications of these noninvasive techniques for textile manufacturing are pointed out.

  8. Quality-Controlled Motion-Compensated Interpolation

    E-print Network

    Girod, Bernd

    results in spatial artifacts especially in video frames with high motion. In the case of lowQuality-Controlled Motion-Compensated Interpolation Mina Makar, Derek Pang, Yao-Chung Lin and Bernd and power-sensitive applications. One way to reduce encoding complexity is to drop frames at the encoder

  9. Quality control in the secretory pathway

    Microsoft Academic Search

    Craig Hammond; Ari Helenius

    1995-01-01

    Whereas newly synthesized proteins that have aquired a properly folded and assembled structure are transported from the endoplasmic reticulum to their final destinations, incompletely folded and assembled proteins are, as a rule, retained and eventually degraded. The molecular mechanisms of this unique molecular sorting phenomenon, called ‘quality control’, have been illuminated by recent studies.

  10. Outsourcing University Degrees: Implications for Quality Control

    ERIC Educational Resources Information Center

    Edwards, Julie; Crosling, Glenda; Edwards, Ron

    2010-01-01

    Education institutions worldwide have and continue to seek opportunities to spread their offerings abroad. While the provision of courses to students located overseas through partner institutions has many advantages, it raises questions about quality control that are not as applicable to other forms of international education. This paper uses a…

  11. Acoustic resonance techniques for quality control

    NASA Astrophysics Data System (ADS)

    Sinha, D. N.

    Acoustic resonance based nondestructive techniques are described that can be used for both process and quality control in manufacturing. The Acoustic Resonance Spectroscopy (AS) technique is highlighted for its capability in fluid property (flow, density, viscosity, and speed of sound) monitoring. Possible applications of these noninvasive techniques for textile manufacturing are pointed out.

  12. Nonlinear Control and Servo Systems Laboratory Exercise 3

    E-print Network

    Como, Giacomo

    with different control objectives in mind, will use the acceleration reference to the inner loop as its controlNonlinear Control and Servo Systems Laboratory Exercise 3 Optimal Control of Pendulum on Cart Pontus Giselsson Department of Automatic Control Lund University Created: Spring 2008 Latest update

  13. Antimicrobial susceptibility testing of Streptococcus pneumoniae and Haemophilus influenzae --internal quality control as a quality tool on a national level.

    PubMed

    Kärpänoja, Pauliina; Nissinen, Antti; Huovinen, Pentti; Sarkkinen, Hannu

    2013-06-01

    Knowledge of the quality and conformity of antimicrobial resistance data is important for comparing resistance rates regionally and over time. In this study, we have evaluated these features of the Finnish national susceptibility surveillance data for two respiratory tract pathogens, Streptococcus pneumoniae and Haemophilus influenzae. For this purpose internal quality control results for two isolates (S. pneumoniae ATCC 49619 and H. influenzae ATCC 49247) were analyzed from 21 clinical microbiology laboratories over a 3-year period. The results show that standardization of the susceptibility testing methods has proceeded well. The number of protocols used for susceptibility testing has declined (from seventeen methods to two with S. pneumoniae and from eleven to three with H. influenzae) and the reproducibility is good. Nevertheless, we noticed that a few laboratories test and report susceptibility results without defined break-points and even include antimicrobials with questionable therapeutic effect. Another non-compliance with the standard was a lack of a regular control system to verify the attainment of the intended quality of results in some laboratories. Interlaboratory analysis of quality control results is a good way to evaluate the quality and conformity of national resistance data. Finnish laboratories have produced very reproducible and accurate susceptibility results in the pre-EUCAST period, which ended in 2011. PMID:23163534

  14. Optimal Airflow Control for Laboratory Air Handling Unit (LAHU) Systems

    E-print Network

    Cui, Y.; Liu, M.; Conger, K.

    2002-01-01

    An optimal airflow control method and procedure have been developed for laboratory air handing unit (LAHU) systems using linear optimization theories. The optimal airflow control minimizes the thermal energy consumption and the cost, and improves...

  15. Statistical quality control through overall vibration analysis

    NASA Astrophysics Data System (ADS)

    Carnero, M. a. Carmen; González-Palma, Rafael; Almorza, David; Mayorga, Pedro; López-Escobar, Carlos

    2010-05-01

    The present study introduces the concept of statistical quality control in automotive wheel bearings manufacturing processes. Defects on products under analysis can have a direct influence on passengers' safety and comfort. At present, the use of vibration analysis on machine tools for quality control purposes is not very extensive in manufacturing facilities. Noise and vibration are common quality problems in bearings. These failure modes likely occur under certain operating conditions and do not require high vibration amplitudes but relate to certain vibration frequencies. The vibration frequencies are affected by the type of surface problems (chattering) of ball races that are generated through grinding processes. The purpose of this paper is to identify grinding process variables that affect the quality of bearings by using statistical principles in the field of machine tools. In addition, an evaluation of the quality results of the finished parts under different combinations of process variables is assessed. This paper intends to establish the foundations to predict the quality of the products through the analysis of self-induced vibrations during the contact between the grinding wheel and the parts. To achieve this goal, the overall self-induced vibration readings under different combinations of process variables are analysed using statistical tools. The analysis of data and design of experiments follows a classical approach, considering all potential interactions between variables. The analysis of data is conducted through analysis of variance (ANOVA) for data sets that meet normality and homoscedasticity criteria. This paper utilizes different statistical tools to support the conclusions such as chi squared, Shapiro-Wilks, symmetry, Kurtosis, Cochran, Hartlett, and Hartley and Krushal-Wallis. The analysis presented is the starting point to extend the use of predictive techniques (vibration analysis) for quality control. This paper demonstrates the existence of predictive variables (high-frequency vibration displacements) that are sensible to the processes setup and the quality of the products obtained. Based on the result of this overall vibration analysis, a second paper will analyse self-induced vibration spectrums in order to define limit vibration bands, controllable every cycle or connected to permanent vibration-monitoring systems able to adjust sensible process variables identified by ANOVA, once the vibration readings exceed established quality limits.

  16. Quality-assurance data for routine water quality analyses by the U. S. Geological Survey laboratory in Troy, New York; July 1993 through June 1995

    USGS Publications Warehouse

    Lincoln, Tricia A.; Horan-Ross, Debra A.; McHale, Michael R.; Lawrence, Gregory B.

    2001-01-01

    A laboratory for analysis of low-ionic strength water has been developed at the U.S. Geological Survey (USGS) office in Troy, N.Y., to analyze samples collected by USGS projects in the Northeast. The laboratory's quality-assurance program is based on internal and interlaboratory quality-assurance samples and quality-control procedures developed to ensure proper sample collection, processing, and analysis. The quality-assurance/quality-control data are stored in the laboratory's SAS data-management system, which provides efficient review, compilation, and plotting of quality-assurance/quality-control data. This report presents and discusses samples analyzed from July 1993 through June 1995. Quality-control results for 18 analytical procedures were evaluated for bias and precision. Control charts show that data from seven of the analytical procedures were biased throughout the analysis period for either high-concentration or low-concentration samples but were within control limits; these procedures were: acid-neutralizing capacity, dissolved inorganic carbon, dissolved organic carbon (soil expulsions), chloride, magnesium, nitrate (colorimetric method), and pH. Three of the analytical procedures were occasionally biased but were within control limits; they were: calcium (high for high-concentration samples for May 1995), dissolved organic carbon (high for highconcentration samples from January through September 1994), and fluoride (high in samples for April and June 1994). No quality-control sample has been developed for the organic monomeric aluminum procedure. Results from the filter-blank and analytical-blank analyses indicate that all analytical procedures in which blanks were run were within control limits, although values for a few blanks were outside the control limits. Blanks were not analyzed for acid-neutralizing capacity, dissolved inorganic carbon, fluoride, nitrate (colorimetric method), or pH. Sampling and analysis precision are evaluated herein in terms of the coefficient of variation obtained for triplicate samples in 14 of the 18 procedures. Data-quality objectives were met by more than 90 percent of the samples analyzed in all procedures except total monomeric aluminum (85 percent of samples met objectives), total aluminum (70 percent of samples met objectives), and dissolved organic carbon (85 percent of samples met objectives). Triplicate samples were not analyzed for ammonium, fluoride, dissolved inorganic carbon, or nitrate (colorimetric method). Results of the USGS interlaboratory Standard Reference Sample Program indicated high data quality with a median result of 3.6 of a possible 4.0. Environment Canada's LRTAP interlaboratory study results indicated that more than 85 percent of the samples met data-quality objectives in 6 of the 12 analyses; exceptions were calcium, dissolved organic carbon, chloride, pH, potassium, and sodium. Data-quality objectives were not met for calcium samples in one LRTAP study, but 94 percent of samples analyzed were within control limits for the remaining studies. Data-quality objectives were not met by 35 percent of samples analyzed for dissolved organic carbon, but 94 percent of sample values were within 20 percent of the most probable value. Data-quality objectives were not met for 30 percent of samples analyzed for chloride, but 90 percent of sample values were within 20 percent of the most probable value. Measurements of samples with a pH above 6.0 were biased high in 54 percent of the samples, although 85 percent of the samples met data-quality objectives for pH measurements below 6.0. Data-quality objectives for potassium and sodium were not met in one study (only 33 percent of the samples analyzed met the objectives), although 85 percent of the sample values were within control limits for the other studies. Measured sodium values were above the upper control limit in all studies. Results from blind reference-sample analyses indicated that data

  17. 10. Interior view of control room in Components Test Laboratory ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. Interior view of control room in Components Test Laboratory (T-27), looking east. The control room is located in the center of the building and abuts the Test Cell 8, 9, and 10 and equipment room wings. Photograph shows upgraded instrumentation, piping, and technological modifications installed in 1997-99 to accommodate component testing requirements for the Atlas V missile. - Air Force Plant PJKS, Systems Integration Laboratory, Components Test Laboratory, Waterton Canyon Road & Colorado Highway 121, Lakewood, Jefferson County, CO

  18. Quantitative Quality Management through Defect Prediction and Statistical Process Control

    E-print Network

    Jalote, Pankaj

    Quantitative Quality Management through Defect Prediction and Statistical Process Control Pankaj of quality management in a software project is to plan suitable quality control activities, and properly, a project's process has many quality control activities for defect identification and removal. The task

  19. Quality Control in Scholarly Publishing: A New Proposal

    E-print Network

    Mizzaro, Stefano

    Quality Control in Scholarly Publishing: A New Proposal Stefano Mizzaro Department of Mathematics quality is threatened, since the traditional quality control mechanism of peer review is often not used (e. Keywords: Scholarly publishing, electronic publishing, quality control, peer re- view. Introduction

  20. Bio-Rad Laboratories Q u a l i t y C o n t r o l Premium Controls for Immunochemistry

    E-print Network

    Rodriguez, Carlos

    Bio-Rad Laboratories Q u a l i t y C o n t r o l Premium Controls for Immunochemistry Powerful Daily QC With Bio-Rad Premium Third Party Controls Optimize your core laboratory performance by taking high-usage quality controls to a Bio-Rad Premium control and experience savings in cost and labor

  1. Application of Digital Control Techniques to a Laboratory Extrusion Process

    Microsoft Academic Search

    K. W. Leffew; M. J. Stiso; De Wilmington; Hermann Langhorst

    1987-01-01

    Extruders are now routinely controlled with digital computer systems and algorithms. In this study, we have installed, debugged, and demonstrated an advanced control algorithm for individual temperature-zone control of a laboratory single screw extruder. The algorithm: ¿ adjusts the parameters of a resident first-order plus deadtime process model with a linear least squares estimator, ¿ adapts the controller parameters to

  2. Philip Morris involvement in the development of an air quality laboratory in El Salvador

    PubMed Central

    Kummerfeldt, C E; Barnoya, J; Bero, L

    2009-01-01

    Background: The tobacco industry has organised research institutions to generate misleading data on indoor air quality, including second-hand smoke exposure and health effects. Objectives: To describe tobacco industry involvement in the organisation and financial support of an air quality research laboratory in El Salvador. Methods: Tobacco industry documents on the internet were systematically searched from August 2007 to February 2008 for air quality studies undertaken in El Salvador, and laboratory personnel were interviewed. Results: Philip Morris sought to establish a network of air quality laboratories throughout Latin America. In El Salvador, in 1997, through Tabacalera de El Salvador (a subsidiary of Philip Morris) and the Salvadoran Foundation for Economic Development (FUSADES), the industry organised an air quality research laboratory. FUSADES was part of the industry’s Latin American Scientific Network, which consisted of doctors hired as consultants who would send air samples from their research to FUSADES. Philip Morris Scientific Affairs personnel hired LabStat, a Canadian-based laboratory, to provide technical assistance to FUSADES (train and assist the laboratory in air quality measurements). In addition, the Washington-based HMS Group successfully implemented a plan to upgrade the laboratory and obtain international certifications. HMS Group also assisted in searching for sustainable funding for FUSADES, including seeking funds from international aid for Hurricane Mitch. Conclusion: Air quality studies that have used the FUSADES laboratory should be carefully interpreted, given the support that this laboratory received from Philip Morris. PMID:19211614

  3. Major: Ecological Systems Design, Air Quality Control and Waste Management

    E-print Network

    Giger, Christine

    1 Major: Ecological Systems Design, Air Quality Control and Waste Management · Being able to solve control technologies · Knowledge in waste management and technologies Module 1: Ecological Systems Design quality control and biogas Waste management and air quality control Examples for combination of Modules

  4. Quality assurance responsibilities as defined by the EPA Good Automated Laboratory Practices (GALPs).

    PubMed

    Fielder, F G; Eleuteri, B A; Gross, E M

    1993-01-01

    In December 1990, the Environmental Protection Agency's (EPA) Office of Information Resources Management (OIRM) issued a draft of the Good Automated Laboratory Practices (GALP). The GALPs developed from a union of existing Federal and EPA regulations and policies, including: the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA) & Toxic Substance Control Act (TSCA), Good Laboratory Practices (GLP), the EPA Information Resources Management Policy (IRMP), and the Computer Security Act of 1987. The GALPs consolidate the regulations and policies to provide a single source of reference, and sever as an extension of the GLP standards (40 CFR 160 & 792). Whereas the GLPs describe acceptable laboratory management practices, the GALPs describe acceptable automated data management practices, and give guidance for standardizing and implementing procedures to ensure the quality and integrity of automated data collection and storage. The GALPs have been formatted to parallel the structure of the GLPs. Just as the GLPs define the responsibilities of the Quality Assurance Unit (QAU) in maintaining good laboratory practices, the GALPs define the responsibilities of the QAU in maintaining good automated data practices. The QAU is charged with (i) maintaining copies of written procedures for the automated data collection system, (ii) performing inspections of laboratory operations utilizing the automated data collection system and reporting findings, (iii) ensuring authorization and documentation of deviations from written procedures, (iv) auditing data and reports from the automated data collection system to ensure they accurately represent the raw data, and (v) maintaining records of the above-defined QAU functions.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:8156208

  5. The earth resources technology satellite - Photographic facility quality control program

    NASA Technical Reports Server (NTRS)

    Shaffer, R. M.

    1973-01-01

    A detailed description is given of the quality control program used in the photographic laboratory of the NASA-ERTS Ground Data Handling System. The product response variables measured include tone reproduction, resolution, and low spatial frequency noise. In addition to product response variables, certain performance parameters of the laboratory printers and processors are frequently measured in order to produce consistent duplications of archival photography. A description is given of the operation and use of a densitometer/computer interface which is used to calculate three tone reproduction response variables - film speed, average gradient, and base plus fog density. This procedure eliminates the need for any hand plotting of D log E curves to manually determine response variables.

  6. Hexosamine pathway and (ER) protein quality control.

    PubMed

    Denzel, Martin S; Antebi, Adam

    2015-04-01

    Aminosugars produced in the hexosamine pathway (HP) are utilized in protein glycosylation reactions involved in protein maturation and cellular signaling. Recent evidence revealed a role of the HP in protein quality control and ageing. Elevation of the HP product UDP-N-acetylglucosamine in the nematode Caenorhabditis elegans results in resistance towards toxic aggregation-prone proteins, and extended lifespan. Glutamine-fructose 6 phosphate aminotransferase (GFAT-1), the HP's key enzyme, is a target of the unfolded protein response (UPR). Thus, cardiac stress in mice results in GFAT-1 activation that triggers a cytoprotective response. Feeding of glucosamine to aged mice increases their life expectancy. Here we discuss HP activation and cellular protein quality control mechanisms that result in stress resistance and suppression of age-related proteotoxicity. PMID:25463841

  7. Mitochondrial quality control in neurodegenerative diseases.

    PubMed

    Dupuis, Luc

    2014-05-01

    Mutations causing genetic forms of Parkinson's disease or hereditary neuropathies have been recently shown to affect key molecular players involved in the recycling of defective mitochondria, most notably PARKIN, PINK1, Mitofusin 2 or dynein heavy chain. Interestingly, the same pathways are also indirectly targeted by multiple other mutations involved in familial forms of amyotrophic lateral sclerosis, Huntington's disease or Alzheimer's disease. These recent genetic results strongly reinforce the notion that defective mitochondrial physiology might cause neurodegeneration. Mitochondrial dysfunction has however been observed in virtually every neurodegenerative disease and appears not restricted to the most vulnerable neuronal populations affected by a given disease. Thus, the mechanisms linking defective mitochondrial quality control to death of selective neuronal populations remain to be identified. This review provides an update on the most recent literature on mitochondrial quality control and its impairment during neurodegenerative diseases. PMID:23958438

  8. Statistical quality control for VLSIC fabrication processes

    SciTech Connect

    Mozumder, P.K.

    1989-01-01

    As the complexity of VLSICs increase and the device dimension shrink, random fluctuations become the main reason limiting the par metric yield. Whenever a new process is developed, the initial yield are low. The rate of climbing the learning curve is slow, i.e., the time necessary to bring the yield above an economically acceptable value can be unacceptably long, resulting in lost revenue and competitive edge in the market. The slow rates of climbing the learning curve and the low initial yields can be countered by using design methodologies that take into account the random fluctuations in the fabrication processes, and using statistical on-line and off-line control during the wafer fabrication. An integrated CAD-CAM approach with profit maximization as the objective is necessary to design and fabricate present day VLSICs. In this thesis the author proposes a methodology for monitoring and statistically controlling VLSIC manufacturing processes as part of an integrated CAD-CAM system. Present day statistical quality control systems fail to function satisfactorily due to lack of in-situ and in-line data, and absence of statistical techniques that take into account the multi-dimensionality of the data. A concerted effort has to be made to increase the number of in-situ parameters that are measured during the fabrication process using new generation equipment and sensors. Algorithms for identifying the minimal set of observable in-situ and in-line parameters that have to be measured to monitor the fabrication process are presented. The methodology for statistical quality control is based on the exploration of the multivariate distribution of the observed in-process parameters in the region of acceptability specified by the customer. Criteria for comparing the distributions of the normal process to that of the process under control are used to make the quality control decisions.

  9. How intense quality control improves hydraulic fracturing

    SciTech Connect

    Ely, J.W. [Ely and Associates, Inc., Houston, TX (United States)

    1996-11-01

    Not unlike the subject of Forced Closure, Intense Quality Control is probably misnamed. What actually is discussed in this article is pilot testing of the fracturing fluids actually pumped at in-situ conditions of temperature and shear. Presented here is development of the need for onsite testing, equipment used, shear and viscosity curves from several jobs showing what went wrong that would otherwise not have been known, and a discussion of borate gel fluids.

  10. Protein Quality Control in the Nucleus

    PubMed Central

    Nielsen, Sofie V.; Poulsen, Esben G.; Rebula, Caio A.; Hartmann-Petersen, Rasmus

    2014-01-01

    In their natural environment, cells are regularly exposed to various stress conditions that may lead to protein misfolding, but also in the absence of stress, misfolded proteins occur as the result of mutations or failures during protein synthesis. Since such partially denatured proteins are prone to aggregate, cells have evolved several elaborate quality control systems to deal with these potentially toxic proteins. First, various molecular chaperones will seize the misfolded protein and either attempt to refold the protein or target it for degradation via the ubiquitin-proteasome system. The degradation of misfolded proteins is clearly compartmentalized, so unique degradation pathways exist for misfolded proteins depending on whether their subcellular localization is ER/secretory, mitochondrial, cytosolic or nuclear. Recent studies, mainly in yeast, have shown that the nucleus appears to be particularly active in protein quality control. Thus, specific ubiquitin-protein ligases located in the nucleus, target not only misfolded nuclear proteins, but also various misfolded cytosolic proteins which are transported to the nucleus prior to their degradation. In comparison, much less is known about these mechanisms in mammalian cells. Here we highlight recent advances in our understanding of nuclear protein quality control, in particular regarding substrate recognition and proteasomal degradation. PMID:25010148

  11. Protocol Development, Treatment Fidelity, Adherence to Treatment, and Quality Control

    PubMed Central

    Page, Stephen J.

    2013-01-01

    Occupational therapy leaders have emphasized the importance of intervention effectiveness research. The CONSORT and TREND checklists have been suggested as useful tools for reporting the results of randomized and nonrandomized studies, respectively. Despite such recommendations, research protocols and reports continue to underutilize the available tools, a situation reflecting limited resources for and experience with the conduct of effectiveness research. To address this issue, and using the CONSORT statement to structure the analysis, this article discusses strategies for optimization of protocol development, treatment fidelity, adherence to treatment, and quality control. We recommend several approaches to increase the quality of research throughout these various processes. Examples of implementation from our laboratory provide evidence of the utility of these strategies. PMID:23433268

  12. Quality management, certification and accreditation in medical laboratories – the view of ECLM

    Microsoft Academic Search

    R. Dybkaer

    1999-01-01

    Increasing demands from health care planners and industrialists conducting clinical trials, as well as general competition,\\u000a are forcing medical laboratories to seek third-party recognition of their quality management systems. There is a tendency\\u000a to move from certification of a laboratory director, via certification of the laboratory quality system (ISO 9000 family),\\u000a to accreditation needing proof of professional and technical competence

  13. GEMHEP multicenter quality control study of PCR detection of GB virus C/hepatitis G virus RNA in serum.

    PubMed

    Bogard, M; Buffet-Janvresse, C; Cantaloube, J F; Biagini, P; Duverlie, G; Castelain, S; Izopet, J; Dubois, M; Defer, C; Lepot, I; Coste, J; Marcellin, P; Martinot-Peignoux, M; Halfon, P; Gerolami, V; Frangeul, L; Pawlotsky, J M; Roudot-Thoraval, F; Dussaix, E; Loiseau, P; Ravera, N; Lewin, P; Lamoril, J; Lerable, J; Lebon, P

    1997-12-01

    PCR is, to date, the only available tool for the detection of GB virus C (GBV-C) and hepatitis G virus (HGV) RNAs. Twenty-two French laboratories participated in a quality control study to assess the sensitivity and specificity of their procedures. The panel included 13 positive controls and 7 negative controls. The laboratories used either in-house PCR techniques adapted from the literature or partly standardized commercial tests. Three laboratories performed faultlessly with the entire panel. Most laboratories had excellent specificity (100% in 20 of 22 laboratories). Sensitivity was acceptable (85 to 100%) in 15 centers and insufficient (38 to 77%) in 7. As with nonstandardized in-house PCR, the commercial assays gave discrepant performances in different laboratories. These results suggest that laboratories willing to use PCR for detection of GBV-C/HGV RNA for research or diagnostic purposes should participate in multicenter quality control trials. PMID:9399538

  14. GEMHEP multicenter quality control study of PCR detection of GB virus C/hepatitis G virus RNA in serum.

    PubMed Central

    Bogard, M; Buffet-Janvresse, C; Cantaloube, J F; Biagini, P; Duverlie, G; Castelain, S; Izopet, J; Dubois, M; Defer, C; Lepot, I; Coste, J; Marcellin, P; Martinot-Peignoux, M; Halfon, P; Gerolami, V; Frangeul, L; Pawlotsky, J M; Roudot-Thoraval, F; Dussaix, E; Loiseau, P; Ravera, N; Lewin, P; Lamoril, J; Lerable, J; Lebon, P

    1997-01-01

    PCR is, to date, the only available tool for the detection of GB virus C (GBV-C) and hepatitis G virus (HGV) RNAs. Twenty-two French laboratories participated in a quality control study to assess the sensitivity and specificity of their procedures. The panel included 13 positive controls and 7 negative controls. The laboratories used either in-house PCR techniques adapted from the literature or partly standardized commercial tests. Three laboratories performed faultlessly with the entire panel. Most laboratories had excellent specificity (100% in 20 of 22 laboratories). Sensitivity was acceptable (85 to 100%) in 15 centers and insufficient (38 to 77%) in 7. As with nonstandardized in-house PCR, the commercial assays gave discrepant performances in different laboratories. These results suggest that laboratories willing to use PCR for detection of GBV-C/HGV RNA for research or diagnostic purposes should participate in multicenter quality control trials. PMID:9399538

  15. Electronic Nose for Quality Control of Colombian Coffee Through the Detection of Defects in ``Cup Tests''

    NASA Astrophysics Data System (ADS)

    Rodríguez, Juan C.; Duran, Cristhian M.; Reyes, Adriana X.

    2009-05-01

    This article presents a preliminary study on the analysis of samples of Colombian coffee for the detection and classification of defects (i.e. using "Cup Tests"), which was conducted in Almacafé quality control laboratory Almacafé in Cúcuta, Colombia). The results obtained show the application of an Electronic Nose (EN), called "A-NOSE," used in the coffee sector for the cupping tests. The results show that e-nose technology can be a useful tool as quality control of coffee grain.

  16. Quality assurance growing pains: a state perspective on implementing an organizational-wide quality system in environmental laboratories.

    PubMed

    Siders, S D

    1999-01-01

    To implement an effective and efficient quality system in a network of established environmental testing laboratories requires a committed long-term effort that is potentially fraught with multiple obstacles. This presentation discusses one state's ongoing efforts at implementing such a system. First is the need to convince management of the rationale for a quality systems-based approach versus the traditional QA/QC program. Once development of a quality system has been sanctioned, a team-based approach utilizing project planning tools is a good way to approach the effort. Resources are assigned to the development of key quality system components, and generally a phased-deployment or roll-out works best. Once implementation is underway, assuring operational utilization and compliance with the quality system are vital steps in the process. Important to successful implementation is ongoing assessment and refinement of the quality system. Fundamental and key elements of the laboratory quality system are numerous and need to work in concert with each other. Quality system elements to be discussed in the presentation range from management and QA roles and functions to the typical documentation of laboratory policies and procedures. Numerous QA assessment tools and other vital quality system practices that play an important role in making a complete quality system are addressed. In addition, efforts must be undertaken to integrate the laboratory quality system with other management systems within the organization. The bottom line is that all environmental laboratories need a quality system more now than ever. Data users need it. Customers' expectations for data quality are high. USEPA policy and/or programs call for it. Additionally, good quality systems can benefit the organization in multiple ways and help avoid the "pay-me-now or pay-me-later" syndrome. In conclusion, all environmental testing laboratories (i.e., academic, private, commercial and especially governmental) need to invest in and implement a quality system based on a recognized standard (e.g., NELAC, ISO 17025, ANSI/ASQC E-4). The author recommends pursuing NELAP laboratory accreditation with a NELAP-recognized accrediting authority. PMID:11191121

  17. Argonne National Laboratory Internal Appraisal Program environment, safety, health/quality assurance oversight

    SciTech Connect

    Winner, G.L.; Siegfried, Y.S.; Forst, S.P.; Meshenberg, M.J.

    1995-06-01

    Argonne National Laboratory`s Internal Appraisal Program has developed a quality assurance team member training program. This program has been developed to provide training to non-quality assurance professionals. Upon successful completion of this training and approval of the Internal Appraisal Program Manager, these personnel are considered qualified to assist in the conduct of quality assurance assessments. The training program has been incorporated into a self-paced, computerized, training session.

  18. Applying fast Fourier transform (FFT) to statistic quality control

    Microsoft Academic Search

    Cui You-xiang; You Jian-xin; Luo Feng

    2010-01-01

    This article presents a FFT method in statistic quality control. Most previous statistic quality control tools can not analysis the quality data in both time and frequency. In this paper, the FFT method is used to transforming our view of the quality signal from time-based to frequency-based, to provide a basis for current decision during production as to when to

  19. The elephant in the room (and how to lead it out): In-clinic laboratory quality challenges.

    PubMed

    Flatland, Bente; Weiser, Glade

    2014-01-01

    Over 30 yr of technological evolution have resulted in sophisticated instrumentation for in-clinic laboratories, yet there is no regulatory oversight of diagnostic testing quality. Long overdue, the veterinary profession must address quality assurance (QA) of diagnostic testing. Each practice must weigh the responsibility for laboratory instrumentation test results that are often a combination of in-clinic and send-out testing. Challenges faced by clinic staff maintaining in-clinic laboratories include lack of training in QA and quality control (QC), lack of emphasis placed on QA/QC by instrument suppliers, QC financial and time costs, and a general lack of laboratory QA/QC support resources in the veterinary community. Possible solutions include increased continuing education opportunities and the provision of guidelines and other resources by national veterinary organizations; specialty certification of veterinary technicians; an increasing role of veterinary clinical pathologists as QA/QC consultants; and development of external quality assessment programs aimed at veterinary practices. The potential exists for animal health companies to lead in this effort by innovating instrument design, providing QC services, and exploiting instrument connectivity to monitor performance. Veterinary laboratory QA/QC is a neglected aspect of the profession. In coming years, veterinarians will hopefully find increased support for this core practice component. PMID:25251431

  20. Prediction Models are Basis for Rational Air Quality Control

    ERIC Educational Resources Information Center

    Daniels, Anders; Bach, Wilfrid

    1973-01-01

    An air quality control scheme employing meteorological diffusion, time averaging and frequency, and cost-benefit models is discussed. The methods outlined provide a constant feedback system for air quality control. Flow charts and maps are included. (BL)

  1. Transformer Thermal Modeling: Improving Reliability Using Data Quality Control

    E-print Network

    1 Transformer Thermal Modeling: Improving Reliability Using Data Quality Control Daniel J. Tylavsky as possible. In this work, we use data-quality control and data-set screening to show that model reliability

  2. 14 CFR 21.147 - Changes in quality control system.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...CERTIFICATION PROCEDURES FOR PRODUCTS AND PARTS Production Certificates § 21.147 Changes in quality control system. After the issue of a production certificate, each change to the quality control system is subject to review by the...

  3. CONTROL ASSAY DEVELOPMENT: METHODOLOGY AND LABORATORY VERIFICATION

    EPA Science Inventory

    The report describes Control Assay Development (CAD), a data acquisition program designed to evaluate the potential applicability of various treatment processes for the control of solid, liquid, and gaseous emissions from coal conversion plants. The CAD program described could be...

  4. An Internet-based real-time control engineering laboratory

    Microsoft Academic Search

    J. W. Overstreet; A. Tzes

    1999-01-01

    Describes the design of generic virtual instruments used for real-time experimentation at Polytechnic University's control engineering laboratory in a remote-access environment. These instruments can be freely downloaded and the remote user can access the laboratory facilities from anywhere at any time. Our Internet-accessed remote laboratory is based on a client\\/server computer configuration. The server, situated near the experiment, transfers to

  5. A DSP-Based Remote Control Laboratory

    Microsoft Academic Search

    Darko Hercog; Bojan Gergic; Suzana Uran; Karel Jezernik

    2007-01-01

    This paper presents a framework for rapid remote experiment implementation in the field of automatic control. The proposed solution is based on in-house developed embedded control hardware and two commercially available software packages. MATLAB\\/Simulink is used for rapid experiment control algorithm development, while LabVIEW is used for the user front-end and remote control. A combination of presented hardware and software

  6. SandiaNationalLaboratoriesSupplierQualityRequirementsfor Build to PrintHardwarePurchases

    E-print Network

    SandiaNationalLaboratoriesSupplierQualityRequirementsfor Build to PrintHardwarePurchases Subject: Surveillance of Supplier andSupplier's Sub-Tier Vendors Note107: Supplier Inspection Records Level 2: (Quality-42(QP-28)O4 Quality AssuranceSupplement to SandiaContractsandPurchaseOrders (- rr-°1I 11/18/04 #12

  7. 9 QUALITY ASSURANCE AND QUALITY CONTROL 9.1 Introduction

    E-print Network

    for their intended use. A quality system is a management system that describes the elements necessary to plan in the use of radioactive materials. There are self-imposed internal quality management systems (e.g., DOE an organization-specific quality system, there is no need to develop new quality management systems, to the extent

  8. [Quality control in pulsed dose rate brachytherapy].

    PubMed

    Métayer, Y; Meyer, P; Brunaud, C; Peiffert, D

    2009-07-01

    A prospective multicenter study (PDR) was leaded on pulsed dose rate brachytherapy over 2 years (2005/2006) in 20 French centres, as part of a programme entitled Stic-PDR and supported by the French ministry of health. Eight hundred and fifty patients were treated for cervix carcinoma with 2D classic or 3D innovative brachytherapy (425 in each arm). The main objectives of this study were to assess the cost of PDR brachytherapy with dose optimization compared to traditional treatments, and to evaluate the complications and local control. A joint programme of quality control was established by the physicists of the different centres, concerning the software treatment planning, the source replacement, the projector and the technical parameters of the course of patient treatment. This technical note lists these controls, and their frequency. PMID:19427253

  9. Research on product design quality control methods based on QFD

    Microsoft Academic Search

    Jianjie Chu; Suihuai Yu; Guoding Chen; Haijun Wang

    2010-01-01

    Product design quality control is one of the important functions of design management. We must carry out design control to design activity in order to achieve the design goal. Through the research on the Quality Function Deployment (QFD) method, this paper proposes that product quality control of design should start from the conceptual design stage. QFD converts user requirements into

  10. Quality Control in Crowdsourcing Systems Mohammad Allahbakhsh1

    E-print Network

    New South Wales, University of

    Quality Control in Crowdsourcing Systems Mohammad Allahbakhsh1 Boualem Benatallah1 Hamid Reza. Quality control is a critical aspect in crowdsourcing. This article proposes a framework for characterizing various dimensions of the quality control in crowdsourcing sys- tems. We also review some existing

  11. Optimal Resource Allocation for the Quality Control Process Pankaj Jalote

    E-print Network

    Jalote, Pankaj

    Optimal Resource Allocation for the Quality Control Process Pankaj Jalote Department of Computer Sc Abstract Software development project employs some Quality Control (QC) process to detect and remove to their injection, quality control (QC) stages frequently follow the develop- ment stages, in addition to the QC

  12. Misfolded proteins partition between two distinct quality control compartments

    E-print Network

    Bedwell, David M.

    ARTICLES Misfolded proteins partition between two distinct quality control compartments Daniel to occur after failure of the cellular protein quality control mechanisms. Here we examine the formation of quality control substrates to either compartment seems to depend on their ubiquitination status

  13. Scoping Document: Water Quality Control Policy on the

    E-print Network

    Scoping Document: Water Quality Control Policy on the Use of Coastal and Estuarine Waters For Power #12;Scoping Document: Water Quality Control Policy on the Use of Coastal and Estuarine Waters Control Board (State Water Board) prepared this Scoping Document: Division of Water Quality Ocean Unit

  14. Exploring former interaction qualities for tomorrow's control room design

    E-print Network

    Reiterer, Harald

    Exploring former interaction qualities for tomorrow's control room design Jens Müller, Tobias This paper addresses the lack of interaction qualities in control rooms by investigating the potential use former interaction qualities for tomorrow's control room design 2 awareness (Wickens 2004) which both

  15. STM Development: A Systematic Approach Focused on Quality Control

    E-print Network

    STM Development: A Systematic Approach Focused on Quality Control "A Lofty Aspiration" Tamzen K · Respect · Long-term commitment #12;STM Development: A Systematic Approach Focused on Quality Control TEAM: A Systematic Approach Focused on Quality Control TEAM 4. Botanist a. Complete species list; plant

  16. SEMIAUTOMATIC QUALITY CONTROL OF TOPOGRAPHIC REFERENCE DATASETS C. Becker a

    E-print Network

    SEMIAUTOMATIC QUALITY CONTROL OF TOPOGRAPHIC REFERENCE DATASETS C. Becker a , U. Breitkopf b , T. B for semiautomatic quality control of existing geospatial data via automatic image analysis using aerial images, high-to-date. As a consequence, quality control has become increasingly important. In the European Norm DIN EN ISO 8402 (1995

  17. New Directions in Measurement for Software Quality Control

    E-print Network

    Suryn, Witold

    of statistical data. In total this provides a framework for quality control in software engineering that is freed1 New Directions in Measurement for Software Quality Control Paul Krause, Bernd Freimut and Witold Suryn Abstract--Assessing and controlling software quality is still an immature discipline. One

  18. Quality control in the year 2000

    PubMed Central

    Schade, Bernd

    1992-01-01

    ‘Just-in-time’ production is a prerequisite for a company to meet the challenges of competition. Manufacturing cycles have been so successfully optimized that release time now has become a significant factor. A vision for a major quality-control (QC) contribution to profitability in this decade seems to be the just-in-time release. Benefits will go beyond cost savings for lower inventory. The earlier detection of problems will reduce rejections and scrap. In addition, problem analysis and problem-solving will be easier. To achieve just-in-time release, advanced automated systems like robots will become the workhorses in QC for high volume pharmaceutical production. The requirements for these systems are extremely high in terms of quality, reliability and ruggedness. Crucial for the success might be advances in use of microelectronics for error checks, system recording, trouble shooting, etc. as well as creative new approaches (for example the use of redundant assay systems). PMID:18924930

  19. Quality control in the year 2000.

    PubMed

    Schade, B

    1992-01-01

    'Just-in-time' production is a prerequisite for a company to meet the challenges of competition. Manufacturing cycles have been so successfully optimized that release time now has become a significant factor. A vision for a major quality-control (QC) contribution to profitability in this decade seems to be the just-in-time release. Benefits will go beyond cost savings for lower inventory. The earlier detection of problems will reduce rejections and scrap. In addition, problem analysis and problem-solving will be easier. To achieve just-in-time release, advanced automated systems like robots will become the workhorses in QC for high volume pharmaceutical production. The requirements for these systems are extremely high in terms of quality, reliability and ruggedness. Crucial for the success might be advances in use of microelectronics for error checks, system recording, trouble shooting, etc. as well as creative new approaches (for example the use of redundant assay systems). PMID:18924930

  20. Application of sigma metrics for the assessment of quality assurance in clinical biochemistry laboratory in India: a pilot study.

    PubMed

    Singh, Bhawna; Goswami, Binita; Gupta, Vinod Kumar; Chawla, Ranjna; Mallika, Venkatesan

    2011-04-01

    Ensuring quality of laboratory services is the need of the hour in the field of health care. Keeping in mind the revolution ushered by six sigma concept in corporate world, health care sector may reap the benefits of the same. Six sigma provides a general methodology to describe performance on sigma scale. We aimed to gauge our laboratory performance by sigma metrics. Internal quality control (QC) data was analyzed retrospectively over a period of 6 months from July 2009 to December 2009. Laboratory mean, standard deviation and coefficient of variation were calculated for all the parameters. Sigma was calculated for both the levels of internal QC. Satisfactory sigma values (>6) were elicited for creatinine, triglycerides, SGOT, CPK-Total and Amylase. Blood urea performed poorly on the sigma scale with sigma <3. The findings of our exercise emphasize the need for detailed evaluation and adoption of ameliorative measures in order to effectuate six sigma standards for all the analytical processes. PMID:22468038

  1. mRNP quality control goes regulatory.

    PubMed

    Mühlemann, Oliver; Jensen, Torben Heick

    2012-02-01

    The accuracy of eukaryotic gene expression relies on efficient quality control (QC). Most steps in the gene expression pathway en route from transcription to translation are error-prone and QC systems have evolved to utilise many of these biochemical processes as checkpoints to monitor the production or function of mRNA-protein particles (mRNPs). Mechanistically, such evaluation of mRNP fitness is based on competition between the opposing activities of mRNP biogenesis and/or function and mRNP turnover. In fact, quite subtle alteration of any parameter can tip the balance between mRNP persistence and degradation and, therefore, QC checkpoints also comprise perfect opportunities for controlling cellular levels of individual or even entire families of transcripts. From this perspective, QC and gene regulation represent two outcomes of the same molecular process. PMID:22154474

  2. Controlling Laboratory Processes From A Personal Computer

    NASA Technical Reports Server (NTRS)

    Will, H.; Mackin, M. A.

    1991-01-01

    Computer program provides natural-language process control from IBM PC or compatible computer. Sets up process-control system that either runs without operator or run by workers who have limited programming skills. Includes three smaller programs. Two of them, written in FORTRAN 77, record data and control research processes. Third program, written in Pascal, generates FORTRAN subroutines used by other two programs to identify user commands with device-driving routines written by user. Also includes set of input data allowing user to define user commands to be executed by computer. Requires personal computer operating under MS-DOS with suitable hardware interfaces to all controlled devices. Also requires FORTRAN 77 compiler and device drivers written by user.

  3. Quality control parameters for Tamra (copper) Bhasma

    PubMed Central

    Jagtap, Chandrashekhar Yuvaraj; Prajapati, Pradeepkumar; Patgiri, Biswajyoti; Shukla, Vinay J.

    2012-01-01

    Background: Metallic Bhasmas are highly valued and have their own importance in Ayurvedic formulations. To testify the Bhasmas various parameters have been told in Rasashastra classics. Tamra Bhasma (TB) with its different properties is used in the treatment of various diseases is quiet famous among the Ayurvedic physicians (Vaidyas). Objectives: The present study was carried out to set up the quality control parameters for the TB by making the use of classical tests along with advanced analytical tools. Settings and Design: Copper wire taken for the preparation of Bhasma was first analyzed for its copper content and then subjected to Shodhana, Marana and Amrutikarana procedures as per the classical references. Final product complied with all the classical parameters like Rekhapurnatwa, Varitaratwa etc. Materials and Methods: After complying with these tests TB was analyzed by advanced analytical techniques like particle size distribution (PSD) analysis, scanning electron microscopy (SEM), and inductive coupled plasma spectrometry (ICP). Results: PSD analysis of TB showed volumetric mean diameter of 28.70 ?m, 50% of the material was below 18.40 ?m size. Particle size less than 2?m were seen in SEM. 56.24 wt % of copper and 23.06 wt % of sulphur was found in ICP-AES. Heavy metals like cadmium, selenium were not detected while others like arsenic, lead and mercury were present in traces. Conclusions: These observations could be specified as the quality control parameters conforming to all the classical tests under the Bhasma Pariksha. PMID:23661863

  4. Ubiquitin Receptors and Protein Quality Control

    PubMed Central

    Wang, Xuejun; Terpstra, Erin J. M.

    2013-01-01

    Protein quality control (PQC) is essential to intracellular proteostasis and is carried out by sophisticated collaboration between molecular chaperones and targeted protein degradation. The latter is performed by proteasome-mediated degradation, chaperone-mediated autophagy (CMA), and selective macroautophagy, and collectively serve as the final line of defense of PQC. Ubiquitination and subsequently ubiquitin (Ub) receptor proteins (e.g., p62 and Ubiquilins) are important common factors for targeting misfolded proteins to multiple quality control destinies, including the proteasome, lysosomes, and perhaps aggresomes, as well as for triggering mitophagy to remove defective mitochondria. PQC inadequacy, particularly proteasome functional insufficiency, has been shown to participate in cardiac pathogenesis. Tremendous advances have been made in unveiling the changes of PQC in cardiac diseases. However, the investigation into the molecular pathways regulating PQC in cardiac (patho)physiology, including the function of most ubiquitin receptor proteins in the heart, has only recently been initiated. A better understanding of molecular mechanisms governing PQC in cardiac physiology and pathology will undoubtedly provide new insights into cardiac pathogenesis and promote the search for novel therapeutic strategies to more effectively battle heart disease. PMID:23046644

  5. Quality Control Planning for the Mother Boards 1. Overview

    E-print Network

    5/29/99 Quality Control Planning for the Mother Boards 1. Overview The quality control is divided, and 1 interface control card. The adders and integrator card will already have already been burned of delay operates as expected. 5. Test TTC and CANbus individually for full control functions § For one 3

  6. Infection Control Procedures in Commercial Dental Laboratories in Jordan

    Microsoft Academic Search

    Ziad Nawaf Al-Dwairi

    The risk of cross-infection in dental clinics and laboratories has attracted the attention of practitioners for the past few years, yet several medical centers have discarded compliance with infection control guidelines, resulting in a non-safe environ- ment for research and medical care. In Jordan, there is lack of known standard infection control programs that are conducted by the Jordanian Dental

  7. Approaches to Quality of Control in Diabetes Care

    Microsoft Academic Search

    F. Chiarelli; A. Verrotti; L. di Ricco; M. de Martino; G. Morgese

    1998-01-01

    Management methods for quality of diabetes care need new approaches because of the poor metabolic control of most of these patients. Poor quality of care generally results from poor instruction and training rather than from misbehaviour of both patients and their families. Structure quality of care (who and where?), process quality (how?, which are the goals, what resolution is taken

  8. Infection control in the pulmonary function test laboratory

    PubMed Central

    Rasam, Shweta Amol; Apte, Komalkirti Keshavkiran; Salvi, Sundeep Santosh

    2015-01-01

    Pulmonary function testing plays a crucial role in the diagnostic evaluation of patients with lung diseases. Cases of cross infection acquired from the pulmonary function laboratory, although rare, have been reported from various countries. It is therefore imperative to identify the risks and potential organisms implicated in cross infections in a pulmonary function test (PFT) laboratory and implement better and more effective infection control procedures, which will help in preventing cross infections. The infrastructure, the daily patient flow, and the prevalent disinfection techniques used in a PFT laboratory, all play a significant role in transmission of infections. Simple measures to tackle the cross infection potential in a PFT laboratory can help reduce this risk to a bare minimum. Use of specialized techniques and equipment can also be of much use in a set up that has a high turnover of patients. This review aims at creating awareness about the possible pathogens and situations commonly encountered in a PFT laboratory. We have attempted to suggest some relevant and useful infection control measures with regard to disinfection, sterilization, and patient planning and segregation to help minimize the risk of cross infections in a PFT laboratory. The review also highlights the lacuna in the current scenario of PFT laboratories in India and the need to develop newer and better methods of infection control, which will be more user-friendly and cost effective. Further studies to study the possible pathogens in a PFT laboratory and evaluate the prevalent infection control strategies will be needed to enable us to draw more precious conclusions, which can lead to more relevant, contextual recommendations for cross infections control in PFT lab in India.

  9. Groundwater-quality and quality-control data for two monitoring wells near Pavillion, Wyoming, April and May 2012

    USGS Publications Warehouse

    Wright, Peter R.; McMahon, Peter B.; Mueller, David K.; Clark, Melanie L.

    2012-01-01

    In June 2010, the U.S. Environmental Protection Agency installed two deep monitoring wells (MW01 and MW02) near Pavillion, Wyoming, to study groundwater quality. During April and May 2012, the U.S Geological Survey, in cooperation with the Wyoming Department of Environmental Quality, collected groundwater-quality data and quality-control data from monitoring well MW01 and, following well redevelopment, quality-control data for monitoring well MW02. Two groundwater-quality samples were collected from well MW01—one sample was collected after purging about 1.5 borehole volumes, and a second sample was collected after purging 3 borehole volumes. Both samples were collected and processed using methods designed to minimize atmospheric contamination or changes to water chemistry. Groundwater-quality samples were analyzed for field water-quality properties (water temperature, pH, specific conductance, dissolved oxygen, oxidation potential); inorganic constituents including naturally occurring radioactive compounds (radon, radium-226 and radium-228); organic constituents; dissolved gasses; stable isotopes of methane, water, and dissolved inorganic carbon; and environmental tracers (carbon-14, chlorofluorocarbons, sulfur hexafluoride, tritium, helium, neon, argon, krypton, xenon, and the ratio of helium-3 to helium-4). Quality-control sample results associated with well MW01 were evaluated to determine the extent to which environmental sample analytical results were affected by bias and to evaluate the variability inherent to sample collection and laboratory analyses. Field documentation, environmental data, and quality-control data for activities that occurred at the two monitoring wells during April and May 2012 are presented.

  10. In-Process Data Quality Control: A Practical Implementation

    Microsoft Academic Search

    Frans J. Kraak; Karel J. de Neef

    1993-01-01

    Timely availability of good quality data from clinical studies is both necessary to meet current standards of good clinical practice and critical to successful clinical research. In-process data quality control is the answer to fulfilling the requirements of data validation while a study is active and immediate correction of observed errors and other problems. To accomplish in-process data quality control,

  11. Stochastic flow modeling for control of manufacturing system quality

    Microsoft Academic Search

    Guillaume Graton; Martin Guay; Jorge Arinez

    2008-01-01

    The importance of quality control and management has long been demonstrated, with quality being shown to be as important as manufacturing productivity. The goal of this paper is to propose an accurate stochastic model that can represent quality data for supervisory control of manufacturing lines. In this paper, we develop a new application of the stochastic-flow modeling (SFM) approach to

  12. The University of Georgia RESEARCH QUALITY CONTROL GUIDE

    E-print Network

    Arnold, Jonathan

    Page 1 The University of Georgia RESEARCH QUALITY CONTROL GUIDE Michael E. Mispagel, Ph.D. Office conducted. This guide will not only provide a standard of quality control for research at UGA, but through that reputation, it is imperative that UGA produce the highest quality research possible, research that is above

  13. Difficulties implementing a quality assurance program at a national laboratory

    SciTech Connect

    Bussolini, P.L.

    1989-01-01

    Personnel who perform scientific research are highly educated, highly motivated professionals who are often leaders in their fields. A recent survey of researchers at Los Alamos shows that they like freedom and peer recognition, and dislike red tape. Rigid, prescriptive quality assurance programs are often fail because they are perceived to limit freedom and peer recognition and enhance red tape. This paper will present some of the reasons for research personnel to have rebelled against quality assurance programs and will offer suggestions for the development of a meaningful and successful quality program.

  14. Water Quality & Pollutant Source Monitoring: Field and Laboratory Procedures. Training Manual.

    ERIC Educational Resources Information Center

    Office of Water Program Operations (EPA), Cincinnati, OH. National Training and Operational Technology Center.

    This training manual presents material on techniques and instrumentation used to develop data in field monitoring programs and related laboratory operations concerned with water quality and pollution monitoring. Topics include: collection and handling of samples; bacteriological, biological, and chemical field and laboratory methods; field…

  15. Sandia National Laboratories, California Air Quality Program annual report.

    SciTech Connect

    Gardizi, Leslee P.; Smith, Richard (ERM, Walnut Creek, CA)

    2009-06-01

    The annual program report provides detailed information about all aspects of the SNL/CA Air Quality Program. It functions as supporting documentation to the SNL/CA Environmental Management System Program Manual. The program report describes the activities undertaken during the past year, and activities planned in future years to implement the Air Quality Program, one of six programs that supports environmental management at SNL/CA.

  16. Audit of the Department of Energy`s Commercial Laboratory Quality Assurance Evaluation Program

    SciTech Connect

    NONE

    1995-06-01

    The Department of Energy (Department), through its contractors, contracts with commercial analytical laboratories for the analysis of samples related to environmental management activities and worker health and safety programs. Over 100 commercial laboratories located throughout the United States perform sample analyses for the Department, Because of problems identified during previous audit work, we initiated our audit to determine whether the Department`s commercial laboratory quality assurance evaluation program was effective and efficient.

  17. Quality Control for RNA-Seq (QuaCRS): An Integrated Quality Control Pipeline

    PubMed Central

    Kroll, Karl W; Mokaram, Nima E; Pelletier, Alexander R; Frankhouser, David E; Westphal, Maximillian S; Stump, Paige A; Stump, Cameron L; Bundschuh, Ralf; Blachly, James S; Yan, Pearlly

    2014-01-01

    QuaCRS (Quality Control for RNA-Seq) is an integrated, simplified quality control (QC) system for RNA-seq data that allows easy execution of several open-source QC tools, aggregation of their output, and the ability to quickly identify quality issues by performing meta-analyses on QC metrics across large numbers of samples in different studies. It comprises two main sections. First is the QC Pack wrapper, which executes three QC tools: FastQC, RNA-SeQC, and selected functions from RSeQC. Combining these three tools into one wrapper provides increased ease of use and provides a much more complete view of sample data quality than any individual tool. Second is the QC database, which displays the resulting metrics in a user-friendly web interface. It was designed to allow users with less computational experience to easily generate and view QC information for their data, to investigate individual samples and aggregate reports of sample groups, and to sort and search samples based on quality. The structure of the QuaCRS database is designed to enable expansion with additional tools and metrics in the future. The source code for not-for-profit use and a fully functional sample user interface with mock data are available at http://bioserv.mps.ohio-state.edu/QuaCRS/. PMID:25368506

  18. Quality Control of Sputum Smears Examination by Re-Reading in a Tuberculosis Screening

    Microsoft Academic Search

    F Majlessi; A Sekhavati; K Qazi Saeedi; A Poorreza

    Background: Sputum smear examination is the basis of diagnosis of tuberculosis and quality control for the correct diagno- sis of tuberculosis is necessary. This study was a method survey and performed with 930 smears with the aim to compare the confidence rate of sputum smear examination reported by one laboratory technician with the findings reported by two technicians in a

  19. Evaluation of Abrupt Grounding as Quality Control Method for HVDC Extruded Cables

    Microsoft Academic Search

    Frank Mauseth; Erling Ildstad; Rolf Hegerberg; Marc Jeroense; Bjørn Sanden; Jan Erik Larsen

    2009-01-01

    This paper presents results from laboratory experiments performed in order to evaluate different methods for quality control of polymeric insulated HVDC cables. In this work, we have investigated the effect of short term (24 h) DC stress followed by rapid grounding of the cable. This is comparable to a voltage step of -Usub0\\/sub at the point of grounding ,and depending

  20. Compost quality control by hyperspectral imaging

    NASA Astrophysics Data System (ADS)

    Bonifazi, Giuseppe; Serranti, Silvia; D'Aniello, Laura

    2008-04-01

    Compost obtained from different organic waste sources (municipal solid waste, biomass, etc.) is more and more utilized as a relatively low-cost product suitable for agricultural purposes reducing at the same time land filling of wastes. Compost product should comply with specific characteristics in order to be competitive with other fertilizer and amendment products. Main aim of the study was to investigate the possibility offered by hyperspectral imaging to evaluate the compost quality in order to develop control strategies to be implemented at plant scale. Reflectance spectra of selected compost samples have been acquired in the visible-near infrared field (VIS-NIR): 400-1000 nm. Correlations have been established between physical-chemical characteristics of the compost products and contaminants (glass and plastic particles) and their detected reflectance spectral signature.

  1. mRNA quality control goes transcriptional

    PubMed Central

    Kilchert, Cornelia; Vasiljeva, Lidia

    2013-01-01

    Eukaryotic mRNAs are extensively processed to generate functional transcripts, which are 5? capped, spliced and 3? polyadenylated. Accumulation of unprocessed (aberrant) mRNAs can be deleterious for the cell, hence processing fidelity is closely monitored by QC (quality control) mechanisms that identify erroneous transcripts and initiate their selective removal. Nucleases including Xrn2/Rat1 and the nuclear exosome have been shown to play an important role in the turnover of aberrant mRNAs. Recently, with the growing appreciation that mRNA processing occurs concomitantly with polII (RNA polymerase II) transcription, it has become evident that QC acts at the transcriptional level in addition to degrading aberrant RNAs. In the present review, we discuss mechanisms that allow cells to co-transcriptionally initiate the removal of RNAs as well as down-regulate transcription of transcripts where processing repeatedly fails. PMID:24256272

  2. VISUAL QUALITY ASSESSMENT USING A CONTRAST GAIN CONTROL MODEL

    E-print Network

    Winkler, Stefan

    VISUAL QUALITY ASSESSMENT USING A CONTRAST GAIN CONTROL MODEL Stefan Winkler Signal Processing://ltswww.epfl.ch/~winkler/ Stefan.Winkler@epfl.ch Abstract - Much of the work on visual quality assessment has been devoted to gray

  3. Air quality investigations of the Sandia National Laboratories Sol se Mete Aerial Cable Facility

    Microsoft Academic Search

    W. M. Gutman; R. J. Silver

    1994-01-01

    The air quality implications of the test and evaluation activities at the Sandia National Laboratories Sol se Mete Aerial Cable Facility are examined. All facets of the activity that affect air quality are considered. Air contaminants produced directly include exhaust products of rocket motors used to accelerate test articles, dust and gas from chemical explosives, and exhaust gases from electricity

  4. Providing Quality Laboratories to Long-Distance Educational Programs.

    ERIC Educational Resources Information Center

    Gammon, Tammy; Sutton, John

    2003-01-01

    North Carolina State University (UNC) has been on the forefront of long-distance education by offering a Bachelor of Science in Engineering with a Mechatronics Concentration at its remote campus located at UNC Asheville. The program demonstrates that long-distance laboratories are feasible and should not be a stumbling block to offering…

  5. Design of Networked Control Systems (NCSs) on the basis of interplays between Quality of Control

    E-print Network

    Paris-Sud XI, Université de

    Design of Networked Control Systems (NCSs) on the basis of interplays between Quality of Control precisely we present a bi-directional relation between the Quality of Control (QoC) provided by the controller and the Quality of Service (QoS) provided by the LAN (relation noted QoSQoC). We present, first

  6. TECHNICAL GUIDANCE DOCUMENT: QUALITY ASSURANCE AND QUALITY CONTROL FOR WASTE CONTAINMENT FACILITIES

    EPA Science Inventory

    This Technical Guidance Document provides comprehensive guidance on procedures for quality assurance and quality control for waste containment facilities. he document includes a discussion of principles and concepts, compacted soil liners, soil drainage systems, geosynthetic drai...

  7. Quality control expert systems: a review of pertinent literature

    Microsoft Academic Search

    Tsuang Kuo; Anil Mital

    1993-01-01

    Statistical quality control (SQC) is an effective tool that ensures quality products and services by means of control charts, the essence of SQC, and sampling plans. While the computation of sample statistics and the development of control charts are routine exercises, the interpretation of chart patterns, trends and the associated diagnosis of assignable causes requires expert knowledge. The present trend

  8. Graduate Lectures and Problems in Quality Control and Engineering Statistics

    E-print Network

    Vardeman, Stephen B.

    Graduate Lectures and Problems in Quality Control and Engineering Statistics: Theory and Methods To Accompany Statistical Quality Assurance Methods for Engineers by Vardeman and Jobe Stephen B. Vardeman V2;Chapter 3 An Introduction to Discrete Stochastic Control Theory/Minimum Variance Control Section 3.6 of V

  9. Multivariate Quality Control Based on Regression-Adiusted Variables

    Microsoft Academic Search

    Douglas M. Hawkins

    1991-01-01

    When performing quality control in a situation in which measures are made of several possibly related variables, it is desirable to use methods that capitalize on the relationship between the variables to provide controls more sensitive than those that may be made on the variables individually. The most common methods of multivariate quality control that assess the vector of variables

  10. Chapter 5: Quality assurance/quality control in stormwater sampling

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Sampling the quality of stormwater presents unique challenges because stormwater flow is relatively short-lived with drastic variability. Furthermore, storm events often occur with little advance warning, outside conventional work hours, and under adverse weather conditions. Therefore, most stormwat...

  11. Remote Control Laboratory Using EJS Applets and TwinCAT Programmable Logic Controllers

    ERIC Educational Resources Information Center

    Besada-Portas, E.; Lopez-Orozco, J. A.; de la Torre, L.; de la Cruz, J. M.

    2013-01-01

    This paper presents a new methodology to develop remote laboratories for systems engineering and automation control courses, based on the combined use of TwinCAT, a laboratory Java server application, and Easy Java Simulations (EJS). The TwinCAT system is used to close the control loop for the selected plants by means of programmable logic…

  12. Science Laboratories and Indoor Air Quality in Schools. Technical Bulletin.

    ERIC Educational Resources Information Center

    Jacobs, Bruce W.

    Some of the issues surrounding the indoor air quality (IAQ) problems presented by science labs are discussed. Described are possible contaminants in labs, such as chemicals and biological organisms, and ways to lessen accidents arising from these sources are suggested. Some of the factors contributing to comfort, such as temperature levels, are…

  13. Quality Control of Self-Monitoring of Blood Glucose: Why and How?

    PubMed Central

    Solnica, Bogdan; Naskalski, Jerzy W.

    2007-01-01

    The control of analytical quality of self-monitoring of blood glucose (SMBG) is recommended as a routine procedure in diabetes management. This control procedure should be easily accessible to patients, convenient, not time-consuming, and provide a reliable assessment of glucose meter performance. Optimally it should be located in the diabetes outpatient clinic. Presently there are two approaches to carrying out SMBG quality control. The first is based on the comparison of results obtained by a controlled glucose meter and use of the laboratory method or point-of-care testing device as a surrogate reference analyzer. The second one is a traditionally organized external quality assessment scheme with use of a dedicated control material, which is distributed to all participants. The recommended allowable meter error in SMBG can be realistically set at 10%. PMID:19888401

  14. A controllable laboratory stock market for modeling real stock markets

    NASA Astrophysics Data System (ADS)

    An, Kenan; Li, Xiaohui; Yang, Guang; Huang, Jiping

    2013-10-01

    Based on the different research approaches, econophysics can be divided into three directions: empirical econophysics, computational econophysics, and experimental econophysics. Because empirical econophysics lacks controllability that is needed to study the impacts of different external conditions and computational econophysics has to adopt artificial decision-making processes that are often deviated from those of real humans, experimental econophysics tends to overcome these problems by offering controllability and using real humans in laboratory experiments. However, to our knowledge, the existing laboratory experiments have not convincingly reappeared the stylized facts (say, scaling) that have been revealed for real economic/financial markets by econophysicists. A most important reason is that in these experiments, discrete trading time makes these laboratory markets deviated from real markets where trading time is naturally continuous. Here we attempt to overcome this problem by designing a continuous double-auction stock-trading market and conducting several human experiments in laboratory. As an initial work, the present artificial financial market can reproduce some stylized facts related to clustering and scaling. Also, it predicts some other scaling in human behavior dynamics that is hard to achieve in real markets due to the difficulty in getting the data. Thus, it becomes possible to study real stock markets by conducting controlled experiments on such laboratory stock markets producing high frequency data.

  15. Sandia National Laboratories Advanced Simulation and Computing (ASC) software quality plan : ASC software quality engineering practices Version 3.0.

    SciTech Connect

    Turgeon, Jennifer L.; Minana, Molly A.; Hackney, Patricia; Pilch, Martin M.

    2009-01-01

    The purpose of the Sandia National Laboratories (SNL) Advanced Simulation and Computing (ASC) Software Quality Plan is to clearly identify the practices that are the basis for continually improving the quality of ASC software products. Quality is defined in the US Department of Energy/National Nuclear Security Agency (DOE/NNSA) Quality Criteria, Revision 10 (QC-1) as 'conformance to customer requirements and expectations'. This quality plan defines the SNL ASC Program software quality engineering (SQE) practices and provides a mapping of these practices to the SNL Corporate Process Requirement (CPR) 001.3.6; 'Corporate Software Engineering Excellence'. This plan also identifies ASC management's and the software project teams responsibilities in implementing the software quality practices and in assessing progress towards achieving their software quality goals. This SNL ASC Software Quality Plan establishes the signatories commitments to improving software products by applying cost-effective SQE practices. This plan enumerates the SQE practices that comprise the development of SNL ASC's software products and explains the project teams opportunities for tailoring and implementing the practices.

  16. Laboratory Research on Self-Control: Applications to Administration

    Microsoft Academic Search

    A. W. Logue

    1998-01-01

    Administrators must sometimes choose between a less delayed but ultimately less valued outcome (impulsiveness) and a more delayed but ultimately more valued outcome (self-control). Which choice is made can affect the long-term health of an administrator's organization. Self-control laboratory research and analysis can be useful in understanding and possibly modifying these choices. This article describes some of the extensive basic

  17. INVESTIGATIONS IN fISH CONTROL I. Laboratories and methods

    E-print Network

    at the Bureau's Fish Control Laboratories at La Crosse, Wis ., and Warm Springs, Ga. The two reports presented and Wildlife La Crosse, Wis. ----- -~ u S DEPARTMENT or THE INTERIOR Bureau of Sport Fisheries and Wildlife and Charles R. Walker, Chemist Bureau of Sport Fisheries and Wildlife La Crosse, Wis. Abstract.--This report

  18. Setting up and running a control research laboratory

    Microsoft Academic Search

    D. S. Bernstein

    2003-01-01

    Setting up and managing a control research laboratory can be a time-consuming and labor-intensive undertaking. The author offers helpful advice based on his own experience, much of it learned by sometimes painful trial and error, in the hope that this advice will help you avoid some of the difficulties that you might otherwise encounter. Questions addressed are whether to build

  19. Food and Nutrition Services Quality Control Management Program.

    ERIC Educational Resources Information Center

    Wimsatt-Fraim, Teresa S.

    A program was conducted to improve the quality of food service through the training of 44 food and nutrition service employees in a 200-bed hospital. A 12-week quality control program was implemented to address four key areas: food temperatures, food accuracy, food quality, and dietary personnel. Learning strategies, emphasizing critical thinking…

  20. Visual quality assessment using a contrast gain control model

    Microsoft Academic Search

    Stefan Winkler

    1999-01-01

    Much of the work on visual quality assessment has been devoted to gray-level images; metrics taking into account color information and the temporal component are still relatively rare. This paper presents a quality metric for color video which is based on a recent contrast gain control model of the human visual system. It is used to assess the quality of

  1. Tree leaf control on low flow water quality in a small Virginia stream

    USGS Publications Warehouse

    Slack, K.V.; Feltz, H.R.

    1968-01-01

    Impaired water quality in a small stream was related to autumn leaf fall from riparian vegetation. Dissolved oxygen and pH decreased, and water color, specific conductance, iron, manganese, and bicarbonate values increased as the rate of leaf fall increased. Similar quality changes occurred in laboratory cultures of tree leaves in filtered stream water, but the five leaf species studied produced widely differing results. Stream quality improved rapidly following channel flushing by storm flow. Organic loading by tree litter can exert significant control on water composition, especially during low flow.

  2. Quality control of diffusion weighted images

    NASA Astrophysics Data System (ADS)

    Liu, Zhexing; Wang, Yi; Gerig, Guido; Gouttard, Sylvain; Tao, Ran; Fletcher, Thomas; Styner, Martin

    2010-03-01

    Diffusion Tensor Imaging (DTI) has become an important MRI procedure to investigate the integrity of white matter in brain in vivo. DTI is estimated from a series of acquired Diffusion Weighted Imaging (DWI) volumes. DWI data suffers from inherent low SNR, overall long scanning time of multiple directional encoding with correspondingly large risk to encounter several kinds of artifacts. These artifacts can be too severe for a correct and stable estimation of the diffusion tensor. Thus, a quality control (QC) procedure is absolutely necessary for DTI studies. Currently, routine DTI QC procedures are conducted manually by visually checking the DWI data set in a gradient by gradient and slice by slice way. The results often suffer from low consistence across different data sets, lack of agreement of different experts, and difficulty to judge motion artifacts by qualitative inspection. Additionally considerable manpower is needed for this step due to the large number of images to QC, which is common for group comparison and longitudinal studies, especially with increasing number of diffusion gradient directions. We present a framework for automatic DWI QC. We developed a tool called DTIPrep which pipelines the QC steps with a detailed protocoling and reporting facility. And it is fully open source. This framework/tool has been successfully applied to several DTI studies with several hundred DWIs in our lab as well as collaborating labs in Utah and Iowa. In our studies, the tool provides a crucial piece for robust DTI analysis in brain white matter study.

  3. Quality control on radiant heaters manufacture

    NASA Astrophysics Data System (ADS)

    González, Daniel A.; Madruga, Francisco J.; Ibarra-Castanedo, Clemente; Conde, Olga; López-Higuera, Jose M.

    2006-04-01

    An inspection process of radiant heaters is presented in this paper. The proposed non destructive testing and evaluation (NDT and E) technique for defect assessment of radiant heaters is based on infrared thermography images properly acquired and processed. The technique can be used in on-line fabrication quality control radiant heaters manufacturing processes. By exciting the heater with a very short electrical pulse, a sequence of thermographic images is captured by an infrared camera and then analyzed. Regardless of the electrical excitation applied to the heating element of the heater, the electrical power supplied will dissipate at the resistor. Provided enough spatial resolution, the heaters could be tested with an infrared camera capturing the radiated heat. The analysis of the heating wire during the heating flank shows differences among pixels corresponding to defective points and pixels belonging to non-defective areas of the wire. The automation is provided by the development of an algorithm that looks for the slope of the heating evolution of each pixel. A Radon Transform based algorithm is here proposed to reduce human intervention providing just one image where an operator could quickly locate possible defects.

  4. Operation logic and functionality of automatic dose rate and image quality control of conventional fluoroscopy

    SciTech Connect

    Lin, Pei-Jan Paul [Department of Radiology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02115 (United States)

    2009-05-15

    New generation of fluoroscopic imaging systems is equipped with spectral shaping filters complemented with sophisticated automatic dose rate and image quality control logic called ''fluoroscopy curve'' or ''trajectory''. Such fluoroscopy curves were implemented first on cardiovascular angiographic imaging systems and are now available on conventional fluoroscopy equipment. This study aims to investigate the control logic operations under the fluoroscopy mode and acquisition mode (equivalent to the legacy spot filming) of a conventional fluoroscopy system typically installed for upper-lower gastrointestinal examinations, interventional endoscopy laboratories, gastrointestinal laboratory, and pain clinics.

  5. Space Shuttle flying qualities and flight control system assessment study

    NASA Technical Reports Server (NTRS)

    Myers, T. T.; Johnston, D. E.; Mcruer, D.

    1982-01-01

    The suitability of existing and proposed flying quality and flight control system criteria for application to the space shuttle orbiter during atmospheric flight phases was assessed. An orbiter experiment for flying qualities and flight control system design criteria is discussed. Orbiter longitudinal and lateral-directional flying characteristics, flight control system lag and time delay considerations, and flight control manipulator characteristics are included. Data obtained from conventional aircraft may be inappropriate for application to the shuttle orbiter.

  6. Quality assurance/quality control procedures for chlorinated hydrocarbons in human breast adipose tissue

    SciTech Connect

    Archibeque-Engle, S.; Tessari, J.D.; Winn, D.T. [Colorado State Univ., Fort Collins, CO (United States)

    1996-12-27

    Extensive literature exists supporting the accumulation of organochlorine pesticides such as DDT [2,2-bis(p-chlorophenyl)-1,1,1-trichloroethane], and polychlorinated biphenyls (PCBs) in human adipose tissue. Debate has surfaced concerning the link between these environmental contaminants and human breast cancer. Accurate residue analysis and proper analytical procedures are critical in determining the extent to which these compounds play a role in human breast cancer. Further, adequate quality assessment/quality control (QA/QC) is critical for reliable residue analysis. The purpose of this research was twofold: (1) to find an appropriate surrogate for human breast adipose tissue for spiking purposes, as human samples are difficult to obtain, and (2) to develop a human breast adipose tissue pool that yields adequate reproducibility with low coefficients of variation (CVs) for each compound of interest. Using a previously validated method developed in the Analytical Laboratory at Colorado State University, rendered ovine adipose tissue was found to be a suitable spiking material, as it was free of interfering compounds and behaved in a manner similar to human breast adipose tissue throughout the analytical method. Further, this analytical method was used to produce data on three control pool preparations: (A) blended human breast adipose tissue (n = 26), (B) blended and partially rendered human breast adipose tissue (n = 12), and (C) fully blended and rendered human breast adipose tissue (n = 15). The CVs between control pools vary up to 20% for a single compound. The most reproducible preparation procedure requires full blending and rendering. 26 refs., 1 fig., 5 tabs.

  7. ContentsContents4466Reliability and quality control

    E-print Network

    Vickers, James

    ContentsContents4466Reliability and quality control 1. Reliability 2. Quality Control Learning outcomes You will first learn about the importance of the concept of reliability applied to systems previous experience with certain mathematical topics this time may vary considerably. 1 #12;Reliability

  8. ER protein quality control and proteasome-mediated protein degradation

    Microsoft Academic Search

    Jeffrey L. Brodsky; Ardythe A. McCracken

    1999-01-01

    A variety of mutant polypeptides that are associated with human disease are targeted for degradation by an endoplasmic reticulum (ER) quality control system. In addition, physiological signals and viral gene products can target the degradation of several ER resident proteins and secreted proteins passing through the ER. Although the mechanism of protein quality control and the site of degradation were

  9. A New Two-Sided Cumulative Sum Quality Control Scheme

    Microsoft Academic Search

    Ronald B. Crosier

    1986-01-01

    A new two-sided cumulative sum quality control scheme is proposed. The new scheme was developed specifically to be generalized to a multivariate cumulative sum quality control scheme. The multivariate version will be examined in a subsequent paper; this article evaluates the univariate version. A comparison of the conventional two-sided cumulative sum scheme and the proposed scheme indicates that the new

  10. A Approach to Clinical Proteomics Data Quality Control and Import

    E-print Network

    Paris-Sud XI, Université de

    A Approach to Clinical Proteomics Data Quality Control and Import Pierre Naubourg, Marinette of experiments results. Our approach aims to ensure the initial quality of data during import into an information sources, and ontologies, which are use as mediators between them. The controls, we propose, ensure

  11. PLANNING GUIDE FOR EVALUATING AGRICULTURAL NONPOINT SOURCE WATER QUALITY CONTROLS

    EPA Science Inventory

    This manual is a guide for water quality planners in the evaluation and selection of agricultural nonpoint source controls for areas ranging in size from individual farms and subwatersheds to large regions. Such controls are specified in water quality plans developed in response ...

  12. Accruals Quality and Internal Control over Financial Reporting

    Microsoft Academic Search

    Jeffrey T. Doyle; Weili Ge; Sarah McVay

    2007-01-01

    We examine the relation between accruals quality and internal controls using 705 firms that disclosed at least one material weakness from August 2002 to November 2005 and find that weaknesses are generally associated with poorly esti- mated accruals that are not realized as cash flows. Further, we find that this relation between weak internal controls and lower accruals quality is

  13. Quality-assurance/quality-control aspects of precipitation monitoring

    SciTech Connect

    Schroder, L.J.; Malo, B.A. (U.S. Geological Survey, Lakewood, CO (US))

    1987-01-01

    The measurement process for precipitation monitoring includes all the components from the collection point to the publication of the data. Seven components identified by a workshop are (in order of their importance): site selection and equipment set-up; sample analysis; sample collection; equipment selection; data recording; data validation; and sample handling. The authors discuss how each component needs to be addressed by the quality-assurance program. This paper describes one approach to address each of the components of the measurement process.

  14. WUSCEEL: Washington University Structural Control and Earthquake Engineering Laboratory

    NSDL National Science Digital Library

    The Washington University Structural Control and Earthquake Engineering Laboratory (WUSCEEL) hosts an active research group, whose work is documented on this site. The Research section has brief descriptions of several different techniques for controlling building motion during earthquakes, experiments performed in the lab, and seismic issues related to bridges. Accompanying each research summary are several journal papers and technical reports that provide much more in-depth discussions of work done at the lab. A few short video clips are also presented, demonstrating principles of base isolation and damper control.

  15. Active control rotor model testing at Princeton's Rotorcraft Dynamics Laboratory

    NASA Technical Reports Server (NTRS)

    Mckillip, Robert M., Jr.

    1988-01-01

    A description of the model helicopter rotor tests currently in progress at Princeton's Rotorcraft Dynamics Laboratory is presented. The tests are designed to provide data for rotor dynamic modeling for use with active control system design. The model rotor to be used incoporates the capability for Individual Blade Control (IBC) or Higher Harmonic Control through the use of a standard swashplate on a three bladed hub. Sample results from the first series of tests are presented, along with the methodology used for state and parameter identification. Finally, pending experiments and possible research directions using this model and test facility are outlined.

  16. Engineering control of airborne disease transmission in animal laboratories.

    PubMed

    Kowalski, W J; Bahnfleth, W P; Carey, D D

    2002-05-01

    We here present a review of the problem of controlling airborne disease transmission in animal research facilities, with emphasis on engineering design and air-treatment technologies. Dilution ventilation, pressurization control, source control, and air disinfection and removal systems are reviewed, and analytical studies on the effects of dilution ventilation, filtration, and ultraviolet germicidal irradiation are summarized. In addition, we discuss practical problems common to laboratory facilities and present a database of potential airborne pathogens and allergens that can be transmitted between humans and animals. We offer some conclusions regarding the design and selection of available technologies and components and provide cost estimates for various air-cleaning systems. PMID:12051655

  17. Piloting Laboratory Quality System Management in Six Health Facilities in Nigeria

    PubMed Central

    Mbah, Henry; Ojo, Emmanuel; Ameh, James; Musuluma, Humphrey; Negedu-Momoh, Olubunmi Ruth; Jegede, Feyisayo; Ojo, Olufunmilayo; Uwakwe, Nkem; Ochei, Kingsley; Dada, Michael; Udah, Donald; Chiegil, Robert; Torpey, Kwasi

    2014-01-01

    Background Achieving accreditation in laboratories is a challenge in Nigeria like in most African countries. Nigeria adopted the World Health Organization Regional Office for Africa Stepwise Laboratory (Quality) Improvement Process Towards Accreditation (WHO/AFRO– SLIPTA) in 2010. We report on FHI360 effort and progress in piloting WHO-AFRO recognition and accreditation preparedness in six health facility laboratories in five different states of Nigeria. Method Laboratory assessments were conducted at baseline, follow up and exit using the WHO/AFRO– SLIPTA checklist. From the total percentage score obtained, the quality status of laboratories were classified using a zero to five star rating, based on the WHO/AFRO quality improvement stepwise approach. Major interventions include advocacy, capacity building, mentorship and quality improvement projects. Results At baseline audit, two of the laboratories attained 1- star while the remaining four were at 0- star. At follow up audit one lab was at 1- star, two at 3-star and three at 4-star. At exit audit, four labs were at 4- star, one at 3-star and one at 2-star rating. One laboratory dropped a ‘star’ at exit audit, while others consistently improved. The two weakest elements at baseline; internal audit (4%) and occurrence/incidence management (15%) improved significantly, with an exit score of 76% and 81% respectively. The elements facility and safety was the major strength across board throughout the audit exercise. Conclusion This effort resulted in measurable and positive impact on the laboratories. We recommend further improvement towards a formal international accreditation status and scale up of WHO/AFRO– SLIPTA implementation in Nigeria. PMID:25542022

  18. Nuclear Technology Series. Course 14: Introduction to Quality Assurance/Quality Control.

    ERIC Educational Resources Information Center

    Technical Education Research Center, Waco, TX.

    This technical specialty course is one of thirty-five courses designed for use by two-year postsecondary institutions in five nuclear technician curriculum areas: (1) radiation protection technician, (2) nuclear instrumentation and control technician, (3) nuclear materials processing technician, (4) nuclear quality-assurance/quality-control

  19. 3D microscopy for microfabrication quality control

    NASA Astrophysics Data System (ADS)

    Muller, Matthew S.; De Jean, Paul D.

    2015-03-01

    A novel stereo microscope adapter, the SweptVue, has been developed to rapidly perform quantitative 3D microscopy for cost-effective microfabrication quality control. The SweptVue adapter uses the left and right stereo channels of an Olympus SZX7 stereo microscope for sample illumination and detection, respectively. By adjusting the temporal synchronization between the illumination lines projected from a Texas Instruments DLP LightCrafter and the rolling shutter on a Point Grey Flea3 CMOS camera, micrometer-scale depth features can be easily and rapidly measured at up to 5 ?m resolution on a variety of microfabricated samples. In this study, the build performance of an industrial-grade Stratasys Object 300 Connex 3D printer was examined. Ten identical parts were 3D printed with a lateral and depth resolution of 42 ?m and 30 ?m, respectively, using both a rigid and flexible Stratasys PolyJet material. Surface elevation precision and accuracy was examined over multiple regions of interest on plateau and hemispherical surfaces. In general, the dimensions of the examined features were reproducible across the parts built using both materials. However, significant systemic lateral and height build errors were discovered, such as: decreased heights when approaching the edges of plateaus, inaccurate height steps, and poor tolerances on channel width. For 3D printed parts to be used in functional applications requiring micro-scale tolerances, they need to conform to specification. Despite appearing identical, our 3D printed parts were found to have a variety of defects that the SweptVue adapter quickly revealed.

  20. Charting methods for internal quality control for competition ELISA.

    PubMed

    2009-01-01

    This chapter deals with relatively simple ways to use control charts to monitor the performance of ELISAs. A rinderpest competition ELISA, for the estimation of antibodies in serum samples, is used to demonstrate the methods. This assay is available in a kit form. Constant evaluation of the use of the kit is part of what is called internal quality control (IQC). Figure 1 shows an overview of the ELISA scheme described in this chapter. The details of the procedure, which involves plotting the data graphically (charting methods), are explained herein. The objectives of charting data are as follows: 1. To keep a constant record of all data. 2. To monitor the assay from plate to plate in any one day's testing. 3. To monitor the tests made from day to day, week to week, year to year. 4. To allow rapid identification of unacceptable results. 5. To allow recognition of reagent problems. 6. To identify trends in results (increasingly poor performance). 7. To identify when a new set of kit reagents is necessary. 8. To allow identification of differences among operators of the assay. 9. To fulfill various criteria for good laboratory practice. 10. To fulfill necessary requirements for external recognition to prove that tests are being performed at an acceptable level (increasingly important when results are used for international trading purposes). PMID:19219591

  1. International Quality Control Is No Easy Task

    ERIC Educational Resources Information Center

    Contreras, Alan

    2008-01-01

    In early March, the European Quality Assurance Register for Higher Education was established under what is called the Bologna Process. The 46 countries involved in the process seek to improve the quality and assessment of higher education throughout Europe, thus facilitating students' mobility among institutions and countries and enhancing…

  2. Hanford Environmental Information System (HEIS). Volume 9, Field Quality Control subject area

    SciTech Connect

    Schreck, R.I. [Westinghouse Hanford Co., Richland, WA (United States)

    1994-04-15

    The purpose of the HEIS Field Quality Control subject area is to manage the data acquired from field quality control samples. Field quality control samples are used to determine if sample contamination has occurred at some point in the sampling process. Four major types of data comprise the Field Quality Control subject area. Data about samples, spike samples, chemical and/or radiologic analysis of field quality control samples, and relationships between field quality control and non-quality control samples.

  3. Pacific Northwest National Laboratory Apatite Investigation at the 100NR2 Quality Assurance Project Plan

    Microsoft Academic Search

    Fix

    2008-01-01

    This Quality Assurance Project Plan provides the quality assurance requirements and processes that will be followed by staff working on the 100-NR-2 Apatite Project. The U.S. Department of Energy, Fluor Hanford, Inc., Pacific Northwest National Laboratory, and the Washington Department of Ecology agreed that the long-term strategy for groundwater remediation at 100-N would include apatite sequestration as the primary treatment,

  4. Integration of data derived from biological variation into the quality management system of medical laboratories

    Microsoft Academic Search

    Carmen Ricós; Virtudes Alvarez; Fernando Cava; JoséVicene García-Lario; Amparo Hernández; CarlosVíctor Jiménez; Joana Minchinela; Carmen Perich; Margarita Simón

    2004-01-01

    A comprehensive overview is given on the current status of quality management in laboratory medicine. Using the three phases: pre-analytical, analytical, and post-analytical, a variety of sub-processes are discussed. Evaluation of this process using innovative statistical tools leads to the conclusion that much can be gained by incorporating the concept of biological variation in quality management system routines, calculations, delta

  5. Off-Line Quality Control In Integrated Circuit Fabrication Using Experimental Design

    NASA Astrophysics Data System (ADS)

    Phadke, M. S.; Kackar, R. N.; Speeney, D. V.; Grieco, M. J.

    1987-04-01

    Off-line quality control is a systematic method of optimizing production processes and product designs. It is widely used in Japan to produce high quality products at low cost. The method was introduced to us by Professor Genichi Taguchi who is a Deming-award winner and a former Director of the Japanese Academy of Quality. In this paper we will i) describe the off-line quality control method, and ii) document our efforts to optimize the process for forming contact windows in 3.5 Aim CMOS circuits fabricated in the Murray Hill Integrated Circuit Design Capability Laboratory. In the fabrication of integrated circuits it is critically important to produce contact windows of size very near the target dimension. Windows which are too small or too large lead to loss of yield. The off-line quality control method has improved both the process quality and productivity. The variance of the window size has been reduced by a factor of four. Also, processing time for window photolithography has been substantially reduced. The key steps of off-line quality control are: i) Identify important manipulatable process factors and their potential working levels. ii) Perform fractional factorial experiments on the process using orthogonal array designs. iii) Analyze the resulting data to determine the optimum operating levels of the factors. Both the process mean and the process variance are considered in this analysis. iv) Conduct an additional experiment to verify that the new factor levels indeed give an improvement.

  6. 40 CFR 81.217 - Southern Indiana Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

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  7. 40 CFR 81.217 - Southern Indiana Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

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  8. 40 CFR 81.216 - Northeast Indiana Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

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  9. 40 CFR 81.215 - East Central Indiana Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

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  10. 40 CFR 81.215 - East Central Indiana Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

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  11. 40 CFR 81.215 - East Central Indiana Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

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  12. 40 CFR 81.217 - Southern Indiana Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

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  13. 40 CFR 81.216 - Northeast Indiana Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

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  14. 40 CFR 81.215 - East Central Indiana Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

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  15. 40 CFR 81.216 - Northeast Indiana Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

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  16. 40 CFR 81.217 - Southern Indiana Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

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  17. 40 CFR 81.216 - Northeast Indiana Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

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  18. 40 CFR 81.216 - Northeast Indiana Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

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  19. 40 CFR 81.215 - East Central Indiana Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

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  20. 40 CFR 81.202 - Northwest Ohio Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

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  1. 40 CFR 81.202 - Northwest Ohio Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

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  2. 40 CFR 81.182 - Northwest Maine Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

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  3. 40 CFR 81.182 - Northwest Maine Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

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  4. 40 CFR 81.182 - Northwest Maine Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

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  5. 40 CFR 81.122 - Mississippi Delta Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

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  6. 40 CFR 81.122 - Mississippi Delta Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

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  7. 40 CFR 81.122 - Mississippi Delta Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

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  8. 40 CFR 81.122 - Mississippi Delta Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

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  9. 40 CFR 81.122 - Mississippi Delta Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

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  10. 40 CFR 81.30 - Southeastern Wisconsin Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

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  11. 40 CFR 81.30 - Southeastern Wisconsin Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

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  12. 40 CFR 81.30 - Southeastern Wisconsin Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

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  13. 40 CFR 81.30 - Southeastern Wisconsin Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

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  14. 40 CFR 81.256 - Northeast Iowa Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

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  15. 40 CFR 81.258 - Northwest Iowa Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...2010-07-01 2010-07-01 false Northwest Iowa Intrastate Air Quality Control Region...Control Regions § 81.258 Northwest Iowa Intrastate Air Quality Control Region. The Northwest Iowa Intrastate Air Quality Control...

  16. 40 CFR 81.260 - South Central Iowa Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 2010-07-01 false South Central Iowa Intrastate Air Quality Control Region...Control Regions § 81.260 South Central Iowa Intrastate Air Quality Control Region. The South Central Iowa Intrastate Air Quality Control...

  17. 40 CFR 81.252 - Northwest Kansas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...2013-07-01 2013-07-01 false Northwest Kansas Intrastate Air Quality Control Region...Control Regions § 81.252 Northwest Kansas Intrastate Air Quality Control Region. The Northwest Kansas Intrastate Air Quality Control...

  18. 40 CFR 81.251 - Northeast Kansas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...2011-07-01 2011-07-01 false Northeast Kansas Intrastate Air Quality Control Region...Control Regions § 81.251 Northeast Kansas Intrastate Air Quality Control Region. The Northeast Kansas Intrastate Air Quality Control...

  19. 40 CFR 81.255 - Southwest Kansas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...2014-07-01 2014-07-01 false Southwest Kansas Intrastate Air Quality Control Region...Control Regions § 81.255 Southwest Kansas Intrastate Air Quality Control Region. The Southwest Kansas Intrastate Air Quality Control...

  20. 40 CFR 81.251 - Northeast Kansas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...2014-07-01 2014-07-01 false Northeast Kansas Intrastate Air Quality Control Region...Control Regions § 81.251 Northeast Kansas Intrastate Air Quality Control Region. The Northeast Kansas Intrastate Air Quality Control...

  1. 40 CFR 81.253 - South Central Kansas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...2012-07-01 false South Central Kansas Intrastate Air Quality Control Region...Control Regions § 81.253 South Central Kansas Intrastate Air Quality Control Region. The South Central Kansas Intrastate Air Quality Control...

  2. 40 CFR 81.25 - Metropolitan Kansas City Interstate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...2010-07-01 false Metropolitan Kansas City Interstate Air Quality Control Region...Control Regions § 81.25 Metropolitan Kansas City Interstate Air Quality Control Region. The Metropolitan Kansas City Interstate Air Quality Control...

  3. 40 CFR 81.251 - Northeast Kansas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...2010-07-01 2010-07-01 false Northeast Kansas Intrastate Air Quality Control Region...Control Regions § 81.251 Northeast Kansas Intrastate Air Quality Control Region. The Northeast Kansas Intrastate Air Quality Control...

  4. 40 CFR 81.252 - Northwest Kansas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...2010-07-01 2010-07-01 false Northwest Kansas Intrastate Air Quality Control Region...Control Regions § 81.252 Northwest Kansas Intrastate Air Quality Control Region. The Northwest Kansas Intrastate Air Quality Control...

  5. 40 CFR 81.254 - Southeast Kansas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...2011-07-01 2011-07-01 false Southeast Kansas Intrastate Air Quality Control Region...Control Regions § 81.254 Southeast Kansas Intrastate Air Quality Control Region. The Southeast Kansas Intrastate Air Quality Control...

  6. 40 CFR 81.252 - Northwest Kansas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...2011-07-01 2011-07-01 false Northwest Kansas Intrastate Air Quality Control Region...Control Regions § 81.252 Northwest Kansas Intrastate Air Quality Control Region. The Northwest Kansas Intrastate Air Quality Control...

  7. 40 CFR 81.25 - Metropolitan Kansas City Interstate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...2011-07-01 false Metropolitan Kansas City Interstate Air Quality Control Region...Control Regions § 81.25 Metropolitan Kansas City Interstate Air Quality Control Region. The Metropolitan Kansas City Interstate Air Quality Control...

  8. 40 CFR 81.25 - Metropolitan Kansas City Interstate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...2013-07-01 false Metropolitan Kansas City Interstate Air Quality Control Region...Control Regions § 81.25 Metropolitan Kansas City Interstate Air Quality Control Region. The Metropolitan Kansas City Interstate Air Quality Control...

  9. 40 CFR 81.252 - Northwest Kansas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...2012-07-01 2012-07-01 false Northwest Kansas Intrastate Air Quality Control Region...Control Regions § 81.252 Northwest Kansas Intrastate Air Quality Control Region. The Northwest Kansas Intrastate Air Quality Control...

  10. 40 CFR 81.254 - Southeast Kansas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...2013-07-01 2013-07-01 false Southeast Kansas Intrastate Air Quality Control Region...Control Regions § 81.254 Southeast Kansas Intrastate Air Quality Control Region. The Southeast Kansas Intrastate Air Quality Control...

  11. 40 CFR 81.253 - South Central Kansas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...2013-07-01 false South Central Kansas Intrastate Air Quality Control Region...Control Regions § 81.253 South Central Kansas Intrastate Air Quality Control Region. The South Central Kansas Intrastate Air Quality Control...

  12. 40 CFR 81.25 - Metropolitan Kansas City Interstate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...2012-07-01 false Metropolitan Kansas City Interstate Air Quality Control Region...Control Regions § 81.25 Metropolitan Kansas City Interstate Air Quality Control Region. The Metropolitan Kansas City Interstate Air Quality Control...

  13. 40 CFR 81.250 - North Central Kansas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...2010-07-01 false North Central Kansas Intrastate Air Quality Control Region...Control Regions § 81.250 North Central Kansas Intrastate Air Quality Control Region. The North Central Kansas Intrastate Air Quality Control...

  14. 40 CFR 81.250 - North Central Kansas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...2012-07-01 false North Central Kansas Intrastate Air Quality Control Region...Control Regions § 81.250 North Central Kansas Intrastate Air Quality Control Region. The North Central Kansas Intrastate Air Quality Control...

  15. 40 CFR 81.251 - Northeast Kansas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...2013-07-01 2013-07-01 false Northeast Kansas Intrastate Air Quality Control Region...Control Regions § 81.251 Northeast Kansas Intrastate Air Quality Control Region. The Northeast Kansas Intrastate Air Quality Control...

  16. 40 CFR 81.253 - South Central Kansas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...2014-07-01 false South Central Kansas Intrastate Air Quality Control Region...Control Regions § 81.253 South Central Kansas Intrastate Air Quality Control Region. The South Central Kansas Intrastate Air Quality Control...

  17. 40 CFR 81.255 - Southwest Kansas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...2013-07-01 2013-07-01 false Southwest Kansas Intrastate Air Quality Control Region...Control Regions § 81.255 Southwest Kansas Intrastate Air Quality Control Region. The Southwest Kansas Intrastate Air Quality Control...

  18. 40 CFR 81.25 - Metropolitan Kansas City Interstate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...2014-07-01 false Metropolitan Kansas City Interstate Air Quality Control Region...Control Regions § 81.25 Metropolitan Kansas City Interstate Air Quality Control Region. The Metropolitan Kansas City Interstate Air Quality Control...

  19. 40 CFR 81.252 - Northwest Kansas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...2014-07-01 2014-07-01 false Northwest Kansas Intrastate Air Quality Control Region...Control Regions § 81.252 Northwest Kansas Intrastate Air Quality Control Region. The Northwest Kansas Intrastate Air Quality Control...

  20. 40 CFR 81.255 - Southwest Kansas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...2012-07-01 2012-07-01 false Southwest Kansas Intrastate Air Quality Control Region...Control Regions § 81.255 Southwest Kansas Intrastate Air Quality Control Region. The Southwest Kansas Intrastate Air Quality Control...

  1. 40 CFR 81.254 - Southeast Kansas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...2010-07-01 2010-07-01 false Southeast Kansas Intrastate Air Quality Control Region...Control Regions § 81.254 Southeast Kansas Intrastate Air Quality Control Region. The Southeast Kansas Intrastate Air Quality Control...

  2. 40 CFR 81.254 - Southeast Kansas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...2014-07-01 2014-07-01 false Southeast Kansas Intrastate Air Quality Control Region...Control Regions § 81.254 Southeast Kansas Intrastate Air Quality Control Region. The Southeast Kansas Intrastate Air Quality Control...

  3. 40 CFR 81.253 - South Central Kansas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...2011-07-01 false South Central Kansas Intrastate Air Quality Control Region...Control Regions § 81.253 South Central Kansas Intrastate Air Quality Control Region. The South Central Kansas Intrastate Air Quality Control...

  4. 40 CFR 81.251 - Northeast Kansas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...2012-07-01 2012-07-01 false Northeast Kansas Intrastate Air Quality Control Region...Control Regions § 81.251 Northeast Kansas Intrastate Air Quality Control Region. The Northeast Kansas Intrastate Air Quality Control...

  5. 40 CFR 81.254 - Southeast Kansas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...2012-07-01 2012-07-01 false Southeast Kansas Intrastate Air Quality Control Region...Control Regions § 81.254 Southeast Kansas Intrastate Air Quality Control Region. The Southeast Kansas Intrastate Air Quality Control...

  6. 40 CFR 81.253 - South Central Kansas Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...2010-07-01 false South Central Kansas Intrastate Air Quality Control Region...Control Regions § 81.253 South Central Kansas Intrastate Air Quality Control Region. The South Central Kansas Intrastate Air Quality Control...

  7. NIF Projects Controls and Information Systems Software Quality Assurance Plan

    SciTech Connect

    Fishler, B

    2011-03-18

    Quality achievement for the National Ignition Facility (NIF) and the National Ignition Campaign (NIC) is the responsibility of the NIF Projects line organization as described in the NIF and Photon Science Directorate Quality Assurance Plan (NIF QA Plan). This Software Quality Assurance Plan (SQAP) is subordinate to the NIF QA Plan and establishes quality assurance (QA) activities for the software subsystems within Controls and Information Systems (CIS). This SQAP implements an activity level software quality assurance plan for NIF Projects as required by the LLNL Institutional Software Quality Assurance Program (ISQAP). Planned QA activities help achieve, assess, and maintain appropriate quality of software developed and/or acquired for control systems, shot data systems, laser performance modeling systems, business applications, industrial control and safety systems, and information technology systems. The objective of this SQAP is to ensure that appropriate controls are developed and implemented for management planning, work execution, and quality assessment of the CIS organization's software activities. The CIS line organization places special QA emphasis on rigorous configuration control, change management, testing, and issue tracking to help achieve its quality goals.

  8. Quality management at Argonne National Laboratory: Status, accomplishments, and lessons learned

    SciTech Connect

    NONE

    1995-06-01

    In April 1992, Argonne National Laboratory (ANL) launched the implementation of quality management (QM) as an initiative of the Laboratory Director. The goal of the program is to seek ways of improving Laboratory performance and effectiveness by drawing from the realm of experiences in the global total quality management movement. The Argonne QM initiative began with fact finding and formulating a strategy for implementation; the emphasis is that the underlying principles of QM should be an integral part of how the Laboratory is managed and operated. A primary theme that has guided the Argonne QM initiative is to consider only those practices that offer the potential for real improvement, make sense, fit the culture, and would be credible to the broad population. In October 1993, the Laboratory began to pilot a targeted set of QM activities selected to produce outcomes important to the Laboratory--strengthening the customer focus, improving work processes, enhancing employee involvement and satisfaction, and institutionalizing QM. This report describes the results of the just-concluded QM development and demonstration phase in terms of detailed strategies, accomplishments, and lessons learned. These results are offered as evidence to support the conclusion that the Argonne QM initiative has achieved value-added results and credibility and is well positioned to support future deployment across the entire Laboratory as an integrated management initiative. Recommendations for follow-on actions to implement future deployment are provided separately.

  9. QUALITY CONTROL IN COTTON SPINNING AND WEAVING. SOME PRACTICAL RESULTS

    Microsoft Academic Search

    F. C. TOY; Alberto Barella; L. Viertel

    1957-01-01

    In this communication the results obtained during the introduction of statistical quality control techniques into six mills with more than 100,000 cotton spinning spindles, and 1,500 looms are described.A brief description of the control methods employed, and the particular manufacturing processes used in each mill are given. The improvements obtained by the application of quality control are studied, in particular,

  10. Teaching Quality Control with Chocolate Chip Cookies

    ERIC Educational Resources Information Center

    Baker, Ardith

    2014-01-01

    Chocolate chip cookies are used to illustrate the importance and effectiveness of control charts in Statistical Process Control. By counting the number of chocolate chips, creating the spreadsheet, calculating the control limits and graphing the control charts, the student becomes actively engaged in the learning process. In addition, examining…

  11. Groundwater plume control with phytotechnologies at Argonne National Laboratory

    Microsoft Academic Search

    S. Rock; M. C. Negri; J. Quinn; J. Wozniak; J. McPherson

    2002-01-01

    In 1999, Argonne National Laboratory-East (ANL-E) designed and installed a series of engineered plantings consisting of a vegetative cover system and approximately 800 hybrid poplars and willows rooting at various predetermined depths. The plants were installed using various methods including Applied Natural Science's TreeWell{reg_sign} system. The goal of the installation was to protect downgradient surface and groundwater by hydraulic control

  12. 33 CFR 385.21 - Quality control.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...RESTORATION PLAN CERP Implementation Processes § 385.21 Quality...intended to be a continuous process throughout project implementation. The Technical Review...designated points during the implementation process that shall be...

  13. Real time quality control of meteorological data used in SRP's emergency response system

    SciTech Connect

    Pendergast, M.M.

    1980-05-01

    The Savannah River Laboratory's WIND minicomputer system allows quick and accurate assessment of an accidental release at the Savannah River Plant using data from eight meteorological towers. The accuracy of the assessment is largely determined by the accuracy of the meteorological data; therefore quality control is important in an emergency response system. Real-time quality control of this data will be added to the WIND system to automatically identify inaccurate data. Currently, the system averages the measurements from the towers to minimize the influence of inaccurate data being used in calculations. The computer code used in the real-time quality control has been previously used to identify inaccurate measurements from the archived tower data.

  14. Requirements for quality control of analytical data for the Environmental Restoration Program

    SciTech Connect

    Engels, J.

    1992-12-01

    The Environmental Restoration (ER) Program was established for the investigation and remediation of inactive US Department of Energy (DOE) sites and facilities that have been declared surplus in terms of their previous uses. The purpose of this document is to Specify ER requirements for quality control (QC) of analytical data. Activities throughout all phases of the investigation may affect the quality of the final data product, thus are subject to control specifications. Laboratory control is emphasized in this document, and field concerns will be addressed in a companion document Energy Systems, in its role of technical coordinator and at the request of DOE-OR, extends the application of these requirements to all participants in ER activities. Because every instance and concern may not be addressed in this document, participants are encouraged to discuss any questions with the ER Quality Assurance (QA) Office, the Analytical Environmental Support Group (AESG), or the Analytical Project Office (APO).

  15. Laboratory Evaluation of a Commercial Microbial Control System

    PubMed Central

    Borchardt, Kenneth A.

    1976-01-01

    A new product, the 3M Brand Microbial Control System for monitoring the reproducibility of Bauer-Kirby susceptibility tests, was compared with standard ATCC strains of Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa. Results are presented from four independent laboratories in which all obvious protocol variables, excluding media and personnel, were identical. Evaluation of the system revealed that the commercial procedure was simple to implement and efficacious and produced results equivalent to those derived from ATCC control strains of E. coli, S. aureus, and P. aeruginosa. Images PMID:821389

  16. Vibration control for precision manufacturing at Sandia National Laboratories

    SciTech Connect

    Hinnerichs, T.; Martinez, D. [Sandia National Labs., Albuquerque, NM (United States). Structural Dynamics and Vibration Control Dept.

    1995-04-01

    Sandia National Laboratories performs R and D in structural dynamics and vibration suppression for precision applications in weapon systems, space, underwater, transportation and civil structures. Over the last decade these efforts have expanded into the areas of active vibration control and ``smart`` structures and material systems. In addition, Sandia has focused major resources towards technology to support weapon product development and agile manufacturing capability for defense and industrial applications. This paper will briefly describe the structural dynamics modeling and verification process currently in place at Sandia that supports vibration control and some specific applications of these techniques to manufacturing in the areas of lithography, machine tools and flexible robotics.

  17. Quality-assurance plan and field methods for quality-of-water activities, U.S. Geological Survey, Idaho National Engineering Laboratory, Idaho

    Microsoft Academic Search

    Mann

    1996-01-01

    Water-quality activities at the Idaho National Engineering Laboratory (INEL) Project Office are part of the US Geological Survey`s (USGS) Water Resources Division (WRD) mission of appraising the quantity and quality of the Nation`s water resources. The purpose of the Quality Assurance Plan (QAP) for water-quality activities performed by the INEL Project Office is to maintain and improve the quality of

  18. Los Alamos National Laboratory Yucca Mountain Site Characterization Project 1995 quality program status report

    SciTech Connect

    Bolivar, S.L.

    1996-07-01

    This status report summarizes the activities and accomplishments of the Los Alamos National Laboratory Yucca Mountain Site Characterization Project`s (YMP`s) quality assurance program for January 1 to September 30, 1995. The report includes major sections on program activities and trend analysis.

  19. Importance of the Primary Radioactivity Standard Laboratory and Implementation of its Quality Management

    SciTech Connect

    Sahagia, Maria; Razdolescu, Anamaria Cristina; Luca, Aurelian; Ivan, Constantin ['Horia Hulubei' National Institute of Physics and Nuclear Engineering (IFIN-HH), 407 Atomistilor Street, PO Box MG-6, Magurele, Ilfov County, RO-077125 (Romania)

    2007-04-23

    The paper presents some specific aspects of the implementation of the quality management in the Radionuclide Metrology Laboratory, from IFIN-HH, the owner of the primary Romanian standard in radioactivity. The description of the accreditation, according to the EN ISO/IEC 17025:2005, is presented.

  20. Lessons Learned from Implementing a Wet Laboratory Molecular Training Workshop for Beach Water Quality Monitoring

    PubMed Central

    Verhougstraete, Marc Paul; Brothers, Sydney; Litaker, Wayne; Blackwood, A. Denene; Noble, Rachel

    2015-01-01

    Rapid molecular testing methods are poised to replace many of the conventional, culture-based tests currently used in fields such as water quality and food science. Rapid qPCR methods have the benefit of being faster than conventional methods and provide a means to more accurately protect public health. However, many scientists and technicians in water and food quality microbiology laboratories have limited experience using these molecular tests. To ensure that practitioners can use and implement qPCR techniques successfully, we developed a week long workshop to provide hands-on training and exposure to rapid molecular methods for water quality management. This workshop trained academic professors, government employees, private industry representatives, and graduate students in rapid qPCR methods for monitoring recreational water quality. Attendees were immersed in these new methods with hands-on laboratory sessions, lectures, and one-on-one training. Upon completion, the attendees gained sufficient knowledge and practice to teach and share these new molecular techniques with colleagues at their respective laboratories. Key findings from this workshop demonstrated: 1) participants with no prior experience could be effectively trained to conduct highly repeatable qPCR analysis in one week; 2) participants with different desirable outcomes required exposure to a range of different platforms and sample processing approaches; and 3) the collaborative interaction amongst newly trained practitioners, workshop leaders, and members of the water quality community helped foster a cohesive cohort of individuals which can advocate powerful cohort for proper implementation of molecular methods. PMID:25822486

  1. Assuring Quality Control of Clinical Education in Multiple Clinical Affiliates.

    ERIC Educational Resources Information Center

    Davis, Judith A.

    A plan was developed to assure equivalency of clinical education among the medical laboratory technician (MLT) programs affiliated with Sandhills Community College. The plan was designed by faculty to monitor the quality of clinical courses offered by the clinical affiliates. The major strategies were to develop competencies, slide/tape modules, a…

  2. Radiological Control Manual Environment, Safety, Health, and Quality Division

    E-print Network

    Wechsler, Risa H.

    Radiological Control Manual Environment, Safety, Health, and Quality Division SLAC-I-720-0A05Z-001 and published by ESHQ Publishing Document Title: Radiological Control Manual Original Publication Date: 1;Radiological Control Manual Table of Contents TABLE OF CONTENTS Publication Data

  3. Low-Emissions Exhaust Quality Control System to Optimize

    E-print Network

    Low-Emissions Exhaust Quality Control System to Optimize DG/CCHP Systems Renewable Energy Research Use (Absorption Chiller, Boiler, others) Exhaust control unit (ExECU) integrated with a prime mover are available for small scale systems, a system to control both temperature and overall flow rate

  4. Control charts for high-quality processes: MAX or CUMAX ?

    E-print Network

    Al Hanbali, Ahmad

    and birth defects, should be avoided as much as possible. In both fields, application of control chartsControl charts for high-quality processes: MAX or CUMAX ? Willem Albers Department of Applied with (very) small failure rates control charts were introduced which are based on subsequent groups of r

  5. Pressure laboratories for parameter controlled experimentation of deep sea environments

    NASA Astrophysics Data System (ADS)

    Steffen, H.; Holscher, B.; Gust, G.; Thomsen, L.

    2003-04-01

    The in-situ examination of deep sea environments poses many challenges and cannot always be optimised which places the researcher at a disadvantage upon encountering high costs, few possibilities of controlling the naturally given parameters such as temperature, pressure or hydrodynamic conditions, and weather conditions while at sea. To overcome these limitations, pressure laboratories are emerging tools for biological, chemical and geological studies. The Department of Ocean Engineering 1 of the Technical University Hamburg-Harburg has been developing different types of pressure laboratories to meet the needs of the natural sciences. Three types of experimental settings were identified for examination and manipulation: experiments with artificial samples, natural samples that have been decompressed during recovery and re-pressurised, and, finally, natural samples in their original, undamaged state. We concentrate on the latter type of settings. For the laboratory simulations, different transfer units are needed for the decompression-free transfer from field site to laboratory, depending on sample type consisting of either fluids, solid-liquid suspensions including small particles and living organisms, or sediment cores. The pressure labs are thus linked to the in-situ site through special sample and transfer units which collect the undisturbed deep sea samples. As a result, laboratory investigation, after sample transfer, is very similar to in-situ analysis, but with the advantage of perfect control of the sample's environment and condition including the hydrodynamics at the sea bed. Two pressure laboratories that accomplish the given investigation tasks with different types of samples for depths down to 5500 m will be presented together with the related technology for sample acquisition. The latest system will be mobile, fully modular, and container based. Examples of experiments, some completed and some in progress, will be shown: Biological experiments include the measurement of pressure effects on bacterial respiration rates and the trapping and observation of deep sea zooplankton. Gas hydrate related experiments address the decomposition of core sampled natural clathrates as well as growth and dissolution of artificial, homogenous gas hydrates under varying environmental parameters such as pressure, temperature and boundary layer stress (see Drews et al.). Drews, M. et al.: Simulating the dissolution of gas hydrates at the deep sea floor in the pressure chamber under controlled P/T and shear stress conditions, this volume.

  6. The external quality assessment scheme: Five years experience as a participating laboratory

    PubMed Central

    Chaudhary, Rajendra; Das, Sudipta S.; Ojha, Shashank; Khetan, Dheeraj; Sonker, Atul

    2010-01-01

    Background and Aim: Quality assurance in blood banking includes active participation in the external quality program. Such a program offers valuable benefits to patient care, their safety, and an overall quality of laboratory practices. In the year 2002, we participated in the External Quality Assessment Scheme (EQAS) under the World Health Organization (WHO), Bureau of Laboratory Quality Standards, Thailand. Materials and Methods: In the current study we evaluated our EQAS test result of the past five years, from 2003 to 2007. Test results of all blood samples such as ABO grouping, D typing, antibody screening, antibody identification, and transfusion transmitted infection (TTI) testing were analyzed and documented. Results: Discordant results in one or more instances were observed with antibody identification, weak D testing, and tests for anti-HIV1/2 and HBsAg. Twice we failed to detect the ‘anti-Mia’ antibody in the issued sample and that could be attributed to the absence of the corresponding antigen in the used cell panel. HBsAg was missed due to its critically low titer in the serum and the comparatively low sensitivity of our Enzyme-Linked Immunosorbent Assay (ELISA) test kit. Conclusion: All these failures in the last five years have helped us to significantly improve our transfusion service in terms of performance evaluation, patient care and safety issues, and the overall quality of laboratory practices. We therefore recommend all laboratories and hospitals to participate in the EQAS program, which will definitely help them to improve from what they learn. PMID:20376263

  7. Raw sequence data and quality control.

    PubMed

    Bacci, Giovanni

    2015-01-01

    Next-generation sequencing technologies are extensively used in many fields of biology. One of the problems, related to the utilization of this kind of data, is the analysis of raw sequence quality and removal (trimming) of low-quality segments while retaining sufficient information for subsequent analyses. Here, we present a series of methods useful for converting and for refinishing one or more sequence files. One of the methods proposed, based on dynamic trimming, as implemented in the software StreamingTrim allows a fast and accurate trimming of sequence files, with low memory requirement. PMID:25343863

  8. Mesh quality control for multiply-refined tetrahedral grids

    NASA Technical Reports Server (NTRS)

    Biswas, Rupak; Strawn, Roger

    1994-01-01

    A new algorithm for controlling the quality of multiply-refined tetrahedral meshes is presented in this paper. The basic dynamic mesh adaption procedure allows localized grid refinement and coarsening to efficiently capture aerodynamic flow features in computational fluid dynamics problems; however, repeated application of the procedure may significantly deteriorate the quality of the mesh. Results presented show the effectiveness of this mesh quality algorithm and its potential in the area of helicopter aerodynamics and acoustics.

  9. Measurement control at an SRS (Savannah River Site) analytical laboratory

    SciTech Connect

    Wills, G.P.

    1990-01-01

    The measurement control program includes control of the analytical procedures, analyst training and qualification, and mass and balance control. A DEC 11/750 minicomputer and an interfaced Hewlett Packard 9836 desktop computer control these functions. The training and qualification program requires the analyst to analyze known and blind'' standards. Statistical tests for precision and bias are used to determine the analyst's qualification. An analyst must be qualified before he/she is permitted to use an analytical procedure for production samples. The qualified analyst must verify the operation of the measurement system prior to analyzing production samples. Balances must be tested and check-weighed and the analytical procedure must be verified by analyzing a blind'' standard. The data from the analysis is entered to the laboratory computer where it is determined to pass'' or fail.'' The analyst is notified immediately by the laboratory computer if the standard, chemical or mass, has passed. The results of the chemical standard are transferred to a Hewlett Packard computer where the data are evaluated routinely. The evaluation determines the bias and the uncertainty of each analytical procedure as used by the analysts. These parameters are applied to the sample results to bias correct the results and calculate the measurement uncertainty. 1 ref., 2 figs.

  10. Software quality assurance and software safety in the Biomed Control System

    SciTech Connect

    Singh, R.P.; Chu, W.T.; Ludewigt, B.A.; Marks, K.M.; Nyman, M.A.; Renner, T.R.; Stradtner, R.

    1989-10-31

    The Biomed Control System is a hardware/software system used for the delivery, measurement and monitoring of heavy-ion beams in the patient treatment and biology experiment rooms in the Bevalac at the Lawrence Berkeley Laboratory (LBL). This paper describes some aspects of this system including historical background philosophy, configuration management, hardware features that facilitate software testing, software testing procedures, the release of new software quality assurance, safety and operator monitoring. 3 refs.

  11. The making of a successful seminar: Pacific Northwest Laboratory`s {open_quotes}Quest for Quality{close_quotes}

    SciTech Connect

    Lumetta, C.C.; Downs, S.L.; Parnell, K.A.; Allen, R.E.

    1994-10-01

    Five contractors located on or near the Hanford Site in southeastern Washington State support technical communications staffs, all trying to meet the needs of one primary customer the U.S. Department of Energy. Historically, these staffs have maintained different processes and standards with regard to document production, and little interaction or information-sharing has occurred. To begin remedying that situation, the communications staff of Pacific Northwest Laboratory, a multiprogram national laboratory located in Richland, Wash., planned and hosted a one-day {open_quotes}Quest for Quality{close_quotes} seminar. The seminar was the first of its kind to comprise technical communications professionals from all the local DOE prime contractors, including technical editors and writers, publications assistants, text processors, and document production staff. The goals of the seminar were to identify ways to improve the quality of Hanford`s communication products and processes, to strengthen ties among technical communications staffs, and to open the lines of communication for future collaborative efforts. An eight-person committee selected topics, arranged facilities, recruited speakers, coordinated activities, hosted the seminar, and prepared proceedings.

  12. Enzymes in fish processing, biosensors and quality control: A review

    Microsoft Academic Search

    V. Venugopal; R. Lakshmanan; S. N. Doke; D. R. Bongirwar

    2000-01-01

    A number of enzymes have uses in fish processing and quality control. Then?applications may be broadly grouped into: modifications of proteins, enrichment of polyuasaturated fatty acids (PUFA) in lipids, shelf life extension, and as components of biosensors and also in direct assays for quality evaluation of fishery products. Protein processing using proteases include preparation of protein hydrolysates, debittering of protein

  13. Markets segmented by regional-origin labelling with quality control

    Microsoft Academic Search

    Sven Anders; Stanley R. Thompson; Roland Herrmann

    2009-01-01

    It is the objective of this paper to provide a methodological framework for the analysis of regional marketing programs which inlclude regional-origin labelling as well as quality assurance and control. Such programs are increasingly being introduced in Europe and other parts of the world as a means against quality uncertainty in globalized markets. An equilibrim?–?displacement model is developed for a

  14. Unified power quality conditioner with model predictive control

    Microsoft Academic Search

    Zhang Xu; Zhang Wei; Lv Ye; Liu Wutong; Wang Qing

    2010-01-01

    A unified power quality conditioner (UPQC) using model predictive control (MPC) is proposed for improving power quality in a power distribution system. MPC is applied into UPQC to regulate the supply current and the load voltage to the desired reference signals in spite of the existence of harmonic distortions in the supply voltage and the load current, possible sags or

  15. Quality control of ocean temperature and salinity profile data

    Microsoft Academic Search

    Kenneth P. Grembowicz; Betty S. Howell

    2002-01-01

    The objective of data quality control (QC) is to ensure consistency within a single data set or throughout a historical database. This is a vital step to be taken with any data set before scientific analysis can be proceed. A redesign of data quality procedures for temperature and salinity profile data undertaken by the Naval Oceanographic Office (NAVOCEANO) during the

  16. CONTROLLED COMBUSTION OF LOW-QUALITY GAS MIXTURES

    Microsoft Academic Search

    Malinen Kaisu; Järvinen Mika; Saari Kari; Lampinen Markku; Fogelholm Carl-Johan; Riikonen Arto

    The objective of this work was to experimentally de termine the lowest levels of methane content in gas mixtures that would still en able controlled combustion using a commercial standard gas burner. A gas mixture is of low quality when it is uncertai n whether the mixture will ignite or maintain stable combustion. Such low-quality gas mixtures can typically include

  17. Stringent RNA quality control using the Agilent 2100 bioanalyzer

    Microsoft Academic Search

    Guido Krupp

    Successful application of any RNA technology is dependent on the use of high quality RNA. Therefore, RNA isolation has to be followed by a stringent RNA quality control. The Agilent 2100 bioanalyzer in combina- tion with RNA 6000 Nano and Pico LabChip ® kits has become \\

  18. Quantitative quality control in microarray image processing and data acquisition

    Microsoft Academic Search

    Xujing Wang; Soumitra Ghosh; Sun-Wei Guo

    2001-01-01

    A new integrated image analysis package with quanti- tative quality control schemes is described for cDNA microarray technology. The package employs an itera- tive algorithm that utilizes both intensity characteristics and spatial information of the spots on a microarray image for signal-background segmentation and defines five quality scores for each spot to record irreg- ularities in spot intensity, size and

  19. 115. QUALITY CONTROL BOARD FOR MAINTENANCE AND INSPECTION AT SOUTH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    115. QUALITY CONTROL BOARD FOR MAINTENANCE AND INSPECTION AT SOUTH SIDE OF MECHANICAL AND ELECTRICAL ROOM (110), LSB (BLDG. 770), FACING WEST ON EXTERIOR WALL OF QUALITY ASSURANCE ROOM (106A) - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 West, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

  20. Crowdsourcing Quality Control of Online Information: A Quality-Based Cascade Model

    NASA Astrophysics Data System (ADS)

    Fu, Wai-Tat; Liao, Vera

    We extend previous cascade models of social influence to investigate how the exchange of quality information among users may moderate cascade behavior, and the extent to which it may influence the effectiveness of collective user recommendations on quality control of information. We found that while cascades do sometimes occur, their effects depend critically on the accuracies of individual quality assessments of information contents. Contrary to predictions of cascade models of information flow, quality-based cascades tend to reinforce the propagation of individual quality assessments rather than being the primary sources that drive the assessments. We found even small increase in individual accuracies will significantly improve the overall effectiveness of crowdsourcing quality control. Implication to domains such as online health information Web sites or product reviews are discussed.

  1. Evolving Manufacturing Practices: Lessons for the Quality Control Engineer

    E-print Network

    Eagar, Thomas W.

    } Evolving Manufacturing Practices: Lessons for the Quality Control Engineer T hereisa every aspect ofsociety. With- out the wealth generated by manufactur- ing, we will lack the ability to many other manufacturing na- tions and oureducationalsystem hasdete- rioratedmarkedlyinrecentdecades

  2. VERIFICATION TESTING OF AIR POLLUTION CONTROL TECHNOLOGY QUALITY MANAGEMENT PLAN

    EPA Science Inventory

    This document is the basis for quality assurance for the Air Pollution Control Technology Verification Center (APCT Center) operated under the U.S. Environmental Protection Agency (EPA). It describes the policies, organizational structure, responsibilities, procedures, and qualit...

  3. 21 CFR 864.8625 - Hematology quality control mixture.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES HEMATOLOGY AND PATHOLOGY DEVICES Hematology Reagents § 864.8625 Hematology quality control mixture. (a) Identification. A...

  4. 21 CFR 864.8625 - Hematology quality control mixture.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES HEMATOLOGY AND PATHOLOGY DEVICES Hematology Reagents § 864.8625 Hematology quality control mixture. (a) Identification. A...

  5. 21 CFR 864.8625 - Hematology quality control mixture.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES HEMATOLOGY AND PATHOLOGY DEVICES Hematology Reagents § 864.8625 Hematology quality control mixture. (a) Identification. A...

  6. 21 CFR 864.8625 - Hematology quality control mixture.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES HEMATOLOGY AND PATHOLOGY DEVICES Hematology Reagents § 864.8625 Hematology quality control mixture. (a) Identification. A...

  7. Effects of vacuum and controlled atmosphere treatments on insect mortality and lettuce quality.

    PubMed

    Liu, Yong-Biao

    2003-08-01

    Laboratory studies were conducted to determine the effects of vacuum and controlled atmosphere on mortality of aphids, Nasonovia ribisnigri (Mosley) and Macrosiphum euphorbiae (Thomas), and leafminer, Liriomyza langei Frick, and on the visual quality of iceberg lettuce at three different temperatures. Vacuum at 50 mbar and controlled atmosphere with 6% CO2 were effective in controlling aphids and leafminer larvae. Complete control of N. ribisnigri and M. euphorbiae was achieved with vacuum treatments and 6% CO2 CA treatments at 5 degrees C in 4 d. Mortality was >96% when leafminer larvae were treated with vacuum and 6% CO2 CA treatments for 4 d. However, leafminer pupae were more tolerant to the treatments and highest mortality was close to 60% in 4 d with CO2 under vacuum. None of the treatments had negative effects on visual quality of iceberg lettuce. Results from this study are encouraging and warrant further and large-scale research. PMID:14503580

  8. HANDBOOK: QUALITY ASSURANCE/QUALITY CONTROL (QA/QC) PROCEDURES FOR HAZARDOUS WASTE INCINERATION

    EPA Science Inventory

    Resource Conservation and Recovery Act regulations for hazardous waste incineration require trial burns by permit applicants. uality Assurance Project Plan (QAPjP) must accompany a trial burn plan with appropriate quality assurance/quality control procedures. uidance on the prepa...

  9. Quality Assurance and Quality Control Practices For Rehabilitation of Sewer and Water Mains

    EPA Science Inventory

    As part of the US Environmental Protection Agency (EPA)?s Aging Water Infrastructure Research Program, several areas of research are being pursued including a review of quality assurance and quality control (QA/QC) practices and acceptance testing during the installation of rehab...

  10. Development and Testing of a Nuclear Quality Assurance/Quality Control Technician Curriculum. Final Report.

    ERIC Educational Resources Information Center

    Espy, John; And Others

    A project was conducted to field test selected first- and second-year courses in a postsecondary nuclear quality assurance/quality control (QA/QC) technician curriculum and to develop the teaching/learning modules for seven technical specialty courses remaining in the QA/QC technician curriculum. The field testing phase of the project involved the…

  11. COMMUNITY MULTISCALE AIR QUALITY ( CMAQ ) MODEL - QUALITY ASSURANCE AND VERSION CONTROL

    EPA Science Inventory

    This presentation will be given to the EPA Exposure Modeling Workgroup on January 24, 2006. The quality assurance and version control procedures for the Community Multiscale Air Quality (CMAQ) Model are presented. A brief background of CMAQ is given, then issues related to qual...

  12. 40 CFR 81.156 - Southern Maryland Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...2013-07-01 2013-07-01 false Southern Maryland Intrastate Air Quality Control Region...Control Regions § 81.156 Southern Maryland Intrastate Air Quality Control Region. The Southern Maryland Intrastate Air Quality...

  13. 40 CFR 81.156 - Southern Maryland Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...2012-07-01 2012-07-01 false Southern Maryland Intrastate Air Quality Control Region...Control Regions § 81.156 Southern Maryland Intrastate Air Quality Control Region. The Southern Maryland Intrastate Air Quality...

  14. 40 CFR 81.156 - Southern Maryland Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...2010-07-01 2010-07-01 false Southern Maryland Intrastate Air Quality Control Region...Control Regions § 81.156 Southern Maryland Intrastate Air Quality Control Region. The Southern Maryland Intrastate Air Quality...

  15. 40 CFR 81.155 - Central Maryland Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...2010-07-01 2010-07-01 false Central Maryland Intrastate Air Quality Control Region...Control Regions § 81.155 Central Maryland Intrastate Air Quality Control Region. The Central Maryland Intrastate Air Quality...

  16. 40 CFR 81.155 - Central Maryland Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...2011-07-01 2011-07-01 false Central Maryland Intrastate Air Quality Control Region...Control Regions § 81.155 Central Maryland Intrastate Air Quality Control Region. The Central Maryland Intrastate Air Quality...

  17. 40 CFR 81.155 - Central Maryland Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...2014-07-01 2014-07-01 false Central Maryland Intrastate Air Quality Control Region...Control Regions § 81.155 Central Maryland Intrastate Air Quality Control Region. The Central Maryland Intrastate Air Quality...

  18. 40 CFR 81.155 - Central Maryland Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...2013-07-01 2013-07-01 false Central Maryland Intrastate Air Quality Control Region...Control Regions § 81.155 Central Maryland Intrastate Air Quality Control Region. The Central Maryland Intrastate Air Quality...

  19. 40 CFR 81.156 - Southern Maryland Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...2011-07-01 2011-07-01 false Southern Maryland Intrastate Air Quality Control Region...Control Regions § 81.156 Southern Maryland Intrastate Air Quality Control Region. The Southern Maryland Intrastate Air Quality...

  20. 40 CFR 81.156 - Southern Maryland Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...2014-07-01 2014-07-01 false Southern Maryland Intrastate Air Quality Control Region...Control Regions § 81.156 Southern Maryland Intrastate Air Quality Control Region. The Southern Maryland Intrastate Air Quality...

  1. 40 CFR 81.155 - Central Maryland Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...2012-07-01 2012-07-01 false Central Maryland Intrastate Air Quality Control Region...Control Regions § 81.155 Central Maryland Intrastate Air Quality Control Region. The Central Maryland Intrastate Air Quality...

  2. 40 CFR 81.127 - Central New York Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 2011-07-01 false Central New York Intrastate Air Quality Control Region...Control Regions § 81.127 Central New York Intrastate Air Quality Control Region. The Central New York Intrastate Air Quality...

  3. 40 CFR 81.36 - Maricopa Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...Maricopa Intrastate Air Quality Control Region. 81.36 Section 81.36 Protection...PURPOSES Designation of Air Quality Control Regions § 81.36 Maricopa Intrastate Air Quality Control Region. The Phoenix-Tucson Intrastate...

  4. 46 CFR 160.115-15 - Production inspections, tests, quality control, and conformance of winches.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...must— (1) Institute a quality control procedure to ensure...Commandant. The manufacturer's quality control personnel must not... (i) Assuring that the quality control program of the manufacturer...certificates, or invoices from the suppliers identifying all...

  5. 46 CFR 160.115-15 - Production inspections, tests, quality control, and conformance of winches.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...must— (1) Institute a quality control procedure to ensure...Commandant. The manufacturer's quality control personnel must not... (i) Assuring that the quality control program of the manufacturer...certificates, or invoices from the suppliers identifying all...

  6. 46 CFR 160.170-15 - Production inspections, tests, quality control, and conformance of release mechanisms.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...must— (1) Institute a quality control procedure to ensure...Commandant. The manufacturer's quality control personnel must not... (i) Assuring that the quality control program of the manufacturer...certificates, or invoices from the suppliers identifying all...

  7. 46 CFR 160.132-15 - Production inspections, tests, quality control, and conformance of davits.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...must— (1) Institute a quality control procedure to ensure...Commandant. The manufacturer's quality control personnel must not... (i) Assuring that the quality control program of the manufacturer...certificates, or invoices from the suppliers identifying all...

  8. 46 CFR 160.135-15 - Production inspections, tests, quality control, and conformance of lifeboats.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...must— (1) Institute a quality control procedure to ensure...Commandant. The manufacturer's quality control personnel must not... (i) Assuring that the quality control program of the manufacturer...certificates, or invoices from the suppliers identifying all...

  9. 46 CFR 160.170-15 - Production inspections, tests, quality control, and conformance of release mechanisms.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...must— (1) Institute a quality control procedure to ensure...Commandant. The manufacturer's quality control personnel must not... (i) Assuring that the quality control program of the manufacturer...certificates, or invoices from the suppliers identifying all...

  10. 46 CFR 160.115-15 - Production inspections, tests, quality control, and conformance of winches.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...must— (1) Institute a quality control procedure to ensure...Commandant. The manufacturer's quality control personnel must not... (i) Assuring that the quality control program of the manufacturer...certificates, or invoices from the suppliers identifying all...

  11. 46 CFR 160.132-15 - Production inspections, tests, quality control, and conformance of davits.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...must— (1) Institute a quality control procedure to ensure...Commandant. The manufacturer's quality control personnel must not... (i) Assuring that the quality control program of the manufacturer...certificates, or invoices from the suppliers identifying all...

  12. 46 CFR 160.133-15 - Production inspections, tests, quality control, and conformance of release mechanisms.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...must— (1) Institute a quality control procedure to ensure...Commandant. The manufacturer's quality control personnel must not... (i) Assuring that the quality control program of the manufacturer...certificates, or invoices from the suppliers identifying all...

  13. 46 CFR 160.133-15 - Production inspections, tests, quality control, and conformance of release mechanisms.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...must— (1) Institute a quality control procedure to ensure...Commandant. The manufacturer's quality control personnel must not... (i) Assuring that the quality control program of the manufacturer...certificates, or invoices from the suppliers identifying all...

  14. 46 CFR 160.170-15 - Production inspections, tests, quality control, and conformance of release mechanisms.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...must— (1) Institute a quality control procedure to ensure...Commandant. The manufacturer's quality control personnel must not... (i) Assuring that the quality control program of the manufacturer...certificates, or invoices from the suppliers identifying all...

  15. 46 CFR 160.133-15 - Production inspections, tests, quality control, and conformance of release mechanisms.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...must— (1) Institute a quality control procedure to ensure...Commandant. The manufacturer's quality control personnel must not... (i) Assuring that the quality control program of the manufacturer...certificates, or invoices from the suppliers identifying all...

  16. 46 CFR 160.135-15 - Production inspections, tests, quality control, and conformance of lifeboats.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...must— (1) Institute a quality control procedure to ensure...Commandant. The manufacturer's quality control personnel must not... (i) Assuring that the quality control program of the manufacturer...certificates, or invoices from the suppliers identifying all...

  17. 46 CFR 160.132-15 - Production inspections, tests, quality control, and conformance of davits.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...must— (1) Institute a quality control procedure to ensure...Commandant. The manufacturer's quality control personnel must not... (i) Assuring that the quality control program of the manufacturer...certificates, or invoices from the suppliers identifying all...

  18. 46 CFR 160.135-15 - Production inspections, tests, quality control, and conformance of lifeboats.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...must— (1) Institute a quality control procedure to ensure...Commandant. The manufacturer's quality control personnel must not... (i) Assuring that the quality control program of the manufacturer...certificates, or invoices from the suppliers identifying all...

  19. 40 CFR 81.158 - Southern Wisconsin Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...2014-07-01 2014-07-01 false Southern Wisconsin Intrastate Air Quality Control Region...Control Regions § 81.158 Southern Wisconsin Intrastate Air Quality Control Region. The Southern Wisconsin Intrastate Air Quality...

  20. 40 CFR 81.158 - Southern Wisconsin Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...2013-07-01 2013-07-01 false Southern Wisconsin Intrastate Air Quality Control Region...Control Regions § 81.158 Southern Wisconsin Intrastate Air Quality Control Region. The Southern Wisconsin Intrastate Air Quality...

  1. 40 CFR 81.158 - Southern Wisconsin Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...2012-07-01 2012-07-01 false Southern Wisconsin Intrastate Air Quality Control Region...Control Regions § 81.158 Southern Wisconsin Intrastate Air Quality Control Region. The Southern Wisconsin Intrastate Air Quality...

  2. 40 CFR 81.158 - Southern Wisconsin Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...2011-07-01 2011-07-01 false Southern Wisconsin Intrastate Air Quality Control Region...Control Regions § 81.158 Southern Wisconsin Intrastate Air Quality Control Region. The Southern Wisconsin Intrastate Air Quality...

  3. 40 CFR 81.143 - Central Virginia Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...2014-07-01 2014-07-01 false Central Virginia Intrastate Air Quality Control Region...Control Regions § 81.143 Central Virginia Intrastate Air Quality Control Region. The Central Virginia Intrastate Air Quality...

  4. 40 CFR 81.146 - Valley of Virginia Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 2011-07-01 false Valley of Virginia Intrastate Air Quality Control Region...Control Regions § 81.146 Valley of Virginia Intrastate Air Quality Control Region. The Valley of Virginia Intrastate Air Quality...

  5. 40 CFR 81.143 - Central Virginia Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...2013-07-01 2013-07-01 false Central Virginia Intrastate Air Quality Control Region...Control Regions § 81.143 Central Virginia Intrastate Air Quality Control Region. The Central Virginia Intrastate Air Quality...

  6. 40 CFR 81.143 - Central Virginia Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...2010-07-01 2010-07-01 false Central Virginia Intrastate Air Quality Control Region...Control Regions § 81.143 Central Virginia Intrastate Air Quality Control Region. The Central Virginia Intrastate Air Quality...

  7. 40 CFR 81.146 - Valley of Virginia Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 2012-07-01 false Valley of Virginia Intrastate Air Quality Control Region...Control Regions § 81.146 Valley of Virginia Intrastate Air Quality Control Region. The Valley of Virginia Intrastate Air Quality...

  8. 40 CFR 81.143 - Central Virginia Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...2012-07-01 2012-07-01 false Central Virginia Intrastate Air Quality Control Region...Control Regions § 81.143 Central Virginia Intrastate Air Quality Control Region. The Central Virginia Intrastate Air Quality...

  9. 40 CFR 81.146 - Valley of Virginia Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 2010-07-01 false Valley of Virginia Intrastate Air Quality Control Region...Control Regions § 81.146 Valley of Virginia Intrastate Air Quality Control Region. The Valley of Virginia Intrastate Air Quality...

  10. 40 CFR 81.146 - Valley of Virginia Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 2014-07-01 false Valley of Virginia Intrastate Air Quality Control Region...Control Regions § 81.146 Valley of Virginia Intrastate Air Quality Control Region. The Valley of Virginia Intrastate Air Quality...

  11. 40 CFR 81.143 - Central Virginia Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...2011-07-01 2011-07-01 false Central Virginia Intrastate Air Quality Control Region...Control Regions § 81.143 Central Virginia Intrastate Air Quality Control Region. The Central Virginia Intrastate Air Quality...

  12. 40 CFR 81.146 - Valley of Virginia Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 2013-07-01 false Valley of Virginia Intrastate Air Quality Control Region...Control Regions § 81.146 Valley of Virginia Intrastate Air Quality Control Region. The Valley of Virginia Intrastate Air Quality...

  13. 40 CFR 81.168 - Great Falls Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...Designation of Air Quality Control Regions § 81.168 ...Falls Intrastate Air Quality Control Region. The Great Falls Intrastate Air Quality Control Region (Montana...Montana: Blaine County, Cascade County, Chouteau...

  14. 40 CFR 81.168 - Great Falls Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...Designation of Air Quality Control Regions § 81.168 ...Falls Intrastate Air Quality Control Region. The Great Falls Intrastate Air Quality Control Region (Montana...Montana: Blaine County, Cascade County, Chouteau...

  15. 40 CFR 81.97 - Southwest Florida Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...Southwest Florida Intrastate Air Quality Control Region. 81.97 Section...PURPOSES Designation of Air Quality Control Regions § 81.97 Southwest Florida Intrastate Air Quality Control Region. The Southwest...

  16. 40 CFR 81.257 - North Central Iowa Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...North Central Iowa Intrastate Air Quality Control Region. 81.257 Section...PURPOSES Designation of Air Quality Control Regions § 81.257 North Central Iowa Intrastate Air Quality Control Region. The North...

  17. 40 CFR 81.248 - Southeastern Alaska Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...Southeastern Alaska Intrastate Air Quality Control Region. 81.248 Section...PURPOSES Designation of Air Quality Control Regions § 81.248 Southeastern Alaska Intrastate Air Quality Control Region. The Southeastern...

  18. 40 CFR 81.81 - Merrimack Valley-Southern New Hampshire Interstate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...Valley-Southern New Hampshire Interstate Air Quality Control Region. 81.81 Section...PURPOSES Designation of Air Quality Control Regions § 81.81 Merrimack...Valley-Southern New Hampshire Interstate Air Quality Control Region. The Merrimack...

  19. 40 CFR 81.92 - Monroe (Louisiana)-El Dorado (Arkansas) Interstate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...Dorado (Arkansas) Interstate Air Quality Control Region. 81.92 Section...PURPOSES Designation of Air Quality Control Regions § 81.92 Monroe...Dorado (Arkansas) Interstate Air Quality Control Region. The Monroe...

  20. 40 CFR 81.132 - Abilene-Wichita Falls Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...Abilene-Wichita Falls Intrastate Air Quality Control Region. 81.132 Section...PURPOSES Designation of Air Quality Control Regions § 81.132 Abilene-Wichita Falls Intrastate Air Quality Control Region. The...

  1. 40 CFR 81.18 - Metropolitan St. Louis Interstate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...Metropolitan St. Louis Interstate Air Quality Control Region. 81.18 Section...PURPOSES Designation of Air Quality Control Regions § 81.18 Metropolitan St. Louis Interstate Air Quality Control Region. The Metropolitan...

  2. 40 CFR 81.20 - Metropolitan Cincinnati Interstate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...Metropolitan Cincinnati Interstate Air Quality Control Region. 81.20 Section...PURPOSES Designation of Air Quality Control Regions § 81.20 Metropolitan Cincinnati Interstate Air Quality Control Region. The Metropolitan...

  3. 40 CFR 81.39 - Metropolitan Dallas-Fort Worth Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...Dallas-Fort Worth Intrastate Air Quality Control Region. 81.39 Section...PURPOSES Designation of Air Quality Control Regions § 81.39 Metropolitan...Dallas-Fort Worth Intrastate Air Quality Control Region. The...

  4. 40 CFR 81.247 - South Central Alaska Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...Central Alaska Intrastate Air Quality Control Region. 81.247 Section...PURPOSES Designation of Air Quality Control Regions § 81.247 South Central Alaska Intrastate Air Quality Control Region. The South...

  5. 40 CFR 81.115 - Northwest Nevada Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...Northwest Nevada Intrastate Air Quality Control Region. 81.115 Section...PURPOSES Designation of Air Quality Control Regions § 81.115 Northwest Nevada Intrastate Air Quality Control Region. The Northwest...

  6. 40 CFR 81.49 - Southeast Florida Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...Southeast Florida Intrastate Air Quality Control Region. 81.49 Section...PURPOSES Designation of Air Quality Control Regions § 81.49 Southeast Florida Intrastate Air Quality Control Region. The Southeast...

  7. 40 CFR 81.97 - Southwest Florida Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...Southwest Florida Intrastate Air Quality Control Region. 81.97 Section...PURPOSES Designation of Air Quality Control Regions § 81.97 Southwest Florida Intrastate Air Quality Control Region. The Southwest...

  8. 40 CFR 81.148 - Eastern Piedmont Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...Eastern Piedmont Intrastate Air Quality Control Region. 81.148 Section...PURPOSES Designation of Air Quality Control Regions § 81.148 Eastern Piedmont Intrastate Air Quality Control Region. The Eastern...

  9. 40 CFR 81.160 - North Central Coast Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...North Central Coast Intrastate Air Quality Control Region. 81.160 Section...PURPOSES Designation of Air Quality Control Regions § 81.160 North Central Coast Intrastate Air Quality Control Region. The North...

  10. 40 CFR 81.47 - Central Oklahoma Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...Central Oklahoma Intrastate Air Quality Control Region. 81.47 Section...PURPOSES Designation of Air Quality Control Regions § 81.47 Central Oklahoma Intrastate Air Quality Control Region. The Metropolitan...

  11. 40 CFR 81.39 - Metropolitan Dallas-Fort Worth Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...Dallas-Fort Worth Intrastate Air Quality Control Region. 81.39 Section...PURPOSES Designation of Air Quality Control Regions § 81.39 Metropolitan...Dallas-Fort Worth Intrastate Air Quality Control Region. The...

  12. 40 CFR 81.79 - Northeastern Oklahoma Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...Northeastern Oklahoma Intrastate Air Quality Control Region. 81.79 Section...PURPOSES Designation of Air Quality Control Regions § 81.79 Northeastern Oklahoma Intrastate Air Quality Control Region. The Metropolitan...

  13. 40 CFR 81.130 - Southern Tier East Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...Southern Tier East Intrastate Air Quality Control Region. 81.130 Section...PURPOSES Designation of Air Quality Control Regions § 81.130 Southern Tier East Intrastate Air Quality Control Region. The Southern...

  14. 40 CFR 81.29 - Metropolitan Indianapolis Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...Metropolitan Indianapolis Intrastate Air Quality Control Region. 81.29 Section...PURPOSES Designation of Air Quality Control Regions § 81.29 Metropolitan Indianapolis Intrastate Air Quality Control Region. The Metropolitan...

  15. 40 CFR 81.204 - Wilmington-Chillicothe-Logan Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...Wilmington-Chillicothe-Logan Intrastate Air Quality Control Region. 81.204 Section...PURPOSES Designation of Air Quality Control Regions § 81.204 Wilmington-Chillicothe-Logan Intrastate Air Quality Control Region. The...

  16. 40 CFR 81.130 - Southern Tier East Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...Southern Tier East Intrastate Air Quality Control Region. 81.130 Section...PURPOSES Designation of Air Quality Control Regions § 81.130 Southern Tier East Intrastate Air Quality Control Region. The Southern...

  17. 40 CFR 81.83 - Albuquerque-Mid Rio Grande Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...Albuquerque-Mid Rio Grande Intrastate Air Quality Control Region. 81.83 Section...PURPOSES Designation of Air Quality Control Regions § 81.83 Albuquerque-Mid Rio Grande Intrastate Air Quality Control Region. The...

  18. 40 CFR 81.160 - North Central Coast Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...North Central Coast Intrastate Air Quality Control Region. 81.160 Section...PURPOSES Designation of Air Quality Control Regions § 81.160 North Central Coast Intrastate Air Quality Control Region. The North...

  19. 40 CFR 81.214 - Black Hills-Rapid City Intrastate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...Hills-Rapid City Intrastate Air Quality Control Region. 81.214 Section...PURPOSES Designation of Air Quality Control Regions § 81.214 Black Hills-Rapid City Intrastate Air Quality Control Region. The Rapid City...

  20. 42 CFR 84.42 - Proposed quality control plans; approval by the Institute.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...2014-10-01 2014-10-01 false Proposed quality control plans; approval by the Institute. 84...APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Quality Control § 84.42 Proposed quality control plans; approval by the Institute....