Lagrange wavelets for signal processing.
Shi, Z; Wei, G W; Kouri, D J; Hoffman, D K; Bao, Z
2001-01-01
This paper deals with the design of interpolating wavelets based on a variety of Lagrange functions, combined with novel signal processing techniques for digital imaging. Halfband Lagrange wavelets, B-spline Lagrange wavelets and Gaussian Lagrange (Lagrange distributed approximating functional (DAF)) wavelets are presented as specific examples of the generalized Lagrange wavelets. Our approach combines the perceptually dependent visual group normalization (VGN) technique and a softer logic masking (SLM) method. These are utilized to rescale the wavelet coefficients, remove perceptual redundancy and obtain good visual performance for digital image processing. PMID:18255493
ERIC Educational Resources Information Center
Lovell, M.S.
2007-01-01
This paper presents a derivation of all five Lagrange points by methods accessible to sixth-form students, and provides a further opportunity to match Newtonian gravity with centripetal force. The predictive powers of good scientific theories are also discussed with regard to the philosophy of science. Methods for calculating the positions of the…
Lagrange structure and quantization
NASA Astrophysics Data System (ADS)
Kazinski, Peter O.; Lyakhovich, Simon L.; Sharapov, Alexey A.
2005-07-01
A path-integral quantization method is proposed for dynamical systems whose classical equations of motion do not necessarily follow from the action principle. The key new notion behind this quantization scheme is the Lagrange structure which is more general than the lagrangian formalism in the same sense as Poisson geometry is more general than the symplectic one. The Lagrange structure is shown to admit a natural BRST description which is used to construct an AKSZ-type topological sigma-model. The dynamics of this sigma-model in d+1 dimensions, being localized on the boundary, are proved to be equivalent to the original theory in d dimensions. As the topological sigma-model has a well defined action, it is path-integral quantized in the usual way that results in quantization of the original (not necessarily lagrangian) theory. When the original equations of motion come from the action principle, the standard BV path-integral is explicitly deduced from the proposed quantization scheme. The general quantization scheme is exemplified by several models including the ones whose classical dynamics are not variational.
NASA Astrophysics Data System (ADS)
Baye, Daniel
2015-03-01
The Lagrange-mesh method is an approximate variational method taking the form of equations on a grid thanks to the use of a Gauss-quadrature approximation. The variational basis related to this Gauss quadrature is composed of Lagrange functions which are infinitely differentiable functions vanishing at all mesh points but one. This method is quite simple to use and, more importantly, can be very accurate with small number of mesh points for a number of problems. The accuracy may however be destroyed by singularities of the potential term. This difficulty can often be overcome by a regularization of the Lagrange functions which does not affect the simplicity and accuracy of the method. The principles of the Lagrange-mesh method are described, as well as various generalizations of the Lagrange functions and their regularization. The main existing meshes are reviewed and extensive formulas are provided which make the numerical calculations simple. They are in general based on classical orthogonal polynomials. The extensions to non-classical orthogonal polynomials and periodic functions are also presented. Applications start with the calculations of energies, wave functions and some observables for bound states in simple solvable models which can rather easily be used as exercises by the reader. The Dirac equation is also considered. Various problems in the continuum can also simply and accurately be solved with the Lagrange-mesh technique including multichannel scattering or scattering by non-local potentials. The method can be applied to three-body systems in appropriate systems of coordinates. Simple atomic, molecular and nuclear systems are taken as examples. The applications to the time-dependent Schrödinger equation, to the Gross-Pitaevskii equation and to Hartree-Fock calculations are also discussed as well as translations and rotations on a Lagrange mesh.
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Confined helium on Lagrange meshes.
Baye, D; Dohet-Eraly, J
2015-12-21
The Lagrange-mesh method has the simplicity of a calculation on a mesh and can have the accuracy of a variational method. It is applied to the study of a confined helium atom. Two types of confinement are considered. Soft confinements by potentials are studied in perimetric coordinates. Hard confinement in impenetrable spherical cavities is studied in a system of rescaled perimetric coordinates varying in [0,1] intervals. Energies and mean values of the distances between electrons and between an electron and the helium nucleus are calculated. A high accuracy of 11 to 15 significant figures is obtained with small computing times. Pressures acting on the confined atom are also computed. For sphere radii smaller than 1, their relative accuracies are better than 10(-10). For larger radii up to 10, they progressively decrease to 10(-3), still improving the best literature results. PMID:25732054
Relative Motion around Artificial Lagrange Points
NASA Astrophysics Data System (ADS)
Gong, Shengping; Li, Junfeng; Baoyin, Hexi
This work investigates relative motion around the artificial Lagrange points. Two control strategies are used to analyze the stability of relative motion around artificial Lagrange points. The relative motion is strictly unstable and further investigation shows that it diverges very slowly in the vicinity of some artificial Lagrange points. A parameter is defined to quantify instability of the relative motion. Then, the pseudo-stable regions of artificial Lagrange points are given when different values of the parameter are treated as the critical value of pseudo-stability. A large pseudo-stable region exists for one of two control strategies—the passive control strategy. This paper discusses the passive stability design of a sail, and both the attitude and orbital dynamics are considered simultaneously. An artificial Lagrange point in the pseudo-stable region is used to validate the design method. The results show that both the attitude and relative motion are pseudo-stable.
Classical Lagrange Functions for the SME
NASA Astrophysics Data System (ADS)
Russell, N.
2011-12-01
A technique is presented for finding the classical Lagrange function corresponding to a given dispersion relation. This allows us to study the classical analogue of the Standard-Model Extension. Developments are discussed.
Cosmological models with Lagrange multiplier field
NASA Astrophysics Data System (ADS)
Gao, Changjun; Gong, Yan; Wang, Xin; Chen, Xuelei
2011-08-01
We first consider the Einstein-aether theory with a gravitational coupling and a Lagrange multiplier field, and then consider the non-minimally coupled quintessence field theory with Lagrange multiplier field. We study the influence of the Lagrange multiplier field on these models. We show that the energy density evolution of the Einstein-aether field and the quintessence field are significantly modified. The energy density of the Einstein-aether is nearly a constant during the entire history of the Universe. The energy density of the quintessence field can also be kept nearly constant in the matter dominated Universe, or even exhibit a phantom-like behavior for some models. This suggests a possible dynamical origin of the cosmological constant or dark energy. Further more, for the canonical quintessence in the absence of gravitational coupling, we find that the quintessence scalar field can play the role of cold dark matter with the introduction of a Lagrange multiplier field. We conclude that the Lagrange multiplier field could play a very interesting and important role in the construction of cosmological models.
Livermore Unstructured Lagrange Explicit Shock Hydrodynamics
Energy Science and Technology Software Center (ESTSC)
2010-09-21
LULESH v1.0 is a 3D unstructured Lagrange hydrodynamics simulation written specifically to solve a standard analytical test problem, known as the Sedov problem. In this problem, a quantum of energy is deposited into a gas and propagates through the gas over time.
Lagrange Interpolation Learning Particle Swarm Optimization
2016-01-01
In recent years, comprehensive learning particle swarm optimization (CLPSO) has attracted the attention of many scholars for using in solving multimodal problems, as it is excellent in preserving the particles’ diversity and thus preventing premature convergence. However, CLPSO exhibits low solution accuracy. Aiming to address this issue, we proposed a novel algorithm called LILPSO. First, this algorithm introduced a Lagrange interpolation method to perform a local search for the global best point (gbest). Second, to gain a better exemplar, one gbest, another two particle’s historical best points (pbest) are chosen to perform Lagrange interpolation, then to gain a new exemplar, which replaces the CLPSO’s comparison method. The numerical experiments conducted on various functions demonstrate the superiority of this algorithm, and the two methods are proven to be efficient for accelerating the convergence without leading the particle to premature convergence. PMID:27123982
Lagrange Interpolation Learning Particle Swarm Optimization.
Kai, Zhang; Jinchun, Song; Ke, Ni; Song, Li
2016-01-01
In recent years, comprehensive learning particle swarm optimization (CLPSO) has attracted the attention of many scholars for using in solving multimodal problems, as it is excellent in preserving the particles' diversity and thus preventing premature convergence. However, CLPSO exhibits low solution accuracy. Aiming to address this issue, we proposed a novel algorithm called LILPSO. First, this algorithm introduced a Lagrange interpolation method to perform a local search for the global best point (gbest). Second, to gain a better exemplar, one gbest, another two particle's historical best points (pbest) are chosen to perform Lagrange interpolation, then to gain a new exemplar, which replaces the CLPSO's comparison method. The numerical experiments conducted on various functions demonstrate the superiority of this algorithm, and the two methods are proven to be efficient for accelerating the convergence without leading the particle to premature convergence. PMID:27123982
Long period coupling terms for Lagrange's equations
NASA Technical Reports Server (NTRS)
1976-01-01
A generalization of that portion of the work of Berger, which deals with the long period coupling effect of certain pairs of zonal harmonics. Long period terms arising from the short short period coupling of zonal harmonics are derived for Lagrange's equations. The formulation is general so that the results are valid for any pairs of zonal harmonics. Formulas are given to generate the various functions and integrals needed for the results given. Checks have been made against the work of Kozai.
Lagrange duality theory for convex control problems
NASA Technical Reports Server (NTRS)
Hager, W. W.; Mitter, S. K.
1976-01-01
The Lagrange dual to a control problem is studied. The principal result based on the Hahn-Banach theorem proves that the dual problem has an optimal solution if there exists an interior point for the constraint set. A complementary slackness condition holds, if the primal problem has an optimal solution. A necessary and sufficient condition for the optimality of solutions to the primal and the dual problem is also presented.
Lagrange multipliers in theories of gravitation
Kichenassamy, S.
1986-05-01
In gravitatinal theories, P-italic-variation (independepent variation of metric and connection) and H-variation (variation of the metric alone) may be reconciled through C-italic-variation (use of Lagrange multipliers ..lambda.. in P-italic-variation). We extend C-italic-variation to fields coupled with gravitational field and elucidate the cases of vanishing ..lambda... We show that the interpretation of ..lambda.. as constraint reaction forces sheds new light on the structure of these theories; we are thus led to question the necessary of relating torsion to spin, and as an alternative to the theory of Dirac particles in Einstein-Cartan space-time, we propose in a Lorentzian space-time a theory in which Lagrange multipliers corresponding to the vanishing of torsion lead to the symmetrization of canonical energy-momentum tensor and avoid the Heisenberg-Pauli-type terms. Lagrange multipliers also serve to reduce the fourth-order differential equations of gravitational quadratic Lagrangians to second-order ones with additional field variables (a scalar P-italic and a traceless tensor P-italic-tilde/sub i//sub j/); this reduction helps to make precise the compatibility of these theories with General Relativity. Simple derivations are also given for Chern and Euler characteristics c-italic/sub 2/ and /sub Chi//sub 2/, and for other identities.
Principal symbol of Euler–Lagrange operators
NASA Astrophysics Data System (ADS)
Fatibene, L.; Garruto, S.
2016-07-01
We shall introduce the principal symbol for quite a general class of (quasi linear) Euler–Lagrange operators and use them to characterise well-posed initial value problems in gauge covariant field theories. We shall clarify how constraints can arise in covariant Lagrangian theories by extending the standard treatment in GR and without resorting to Hamiltonian formalism. Finally as an example of application, we sketch a quantisation procedure based on what is done in LQG by framing it in a more general context which applies to general gauge covariant field theories.
Bilinear modeling via augmented Lagrange multipliers (BALM).
Del Bue, Alessio; Xavier, João; Agapito, Lourdes; Paladini, Marco
2012-08-01
This paper presents a unified approach to solve different bilinear factorization problems in computer vision in the presence of missing data in the measurements. The problem is formulated as a constrained optimization where one of the factors must lie on a specific manifold. To achieve this, we introduce an equivalent reformulation of the bilinear factorization problem that decouples the core bilinear aspect from the manifold specificity. We then tackle the resulting constrained optimization problem via Augmented Lagrange Multipliers. The strength and the novelty of our approach is that this framework can seamlessly handle different computer vision problems. The algorithm is such that only a projector onto the manifold constraint is needed. We present experiments and results for some popular factorization problems in computer vision such as rigid, non-rigid, and articulated Structure from Motion, photometric stereo, and 2D-3D non-rigid registration. PMID:22156102
Mechanics, analysis and geometry: 200 years after Lagrange.
NASA Astrophysics Data System (ADS)
Francaviglia, M.
This volume consists of articles written on the occasion of the bicentennial of the publication by J.-Louis Lagrange of his treatise, Mechanique Analytique (1788). This book opened a floodgate of contributions to mechanics by analysis. The resulting volume provides insight and perspective on various research problems in modern topics of physics, astrophysics, mathematics and the history of science. Furthermore it presents a balanced and authoritative account of the different branches and problems of mathematical physics that Lagrange originally studied and developed.
Dark energy from modified gravity with Lagrange multipliers
NASA Astrophysics Data System (ADS)
Capozziello, Salvatore; Matsumoto, Jiro; Nojiri, Shin'ichi; Odintsov, Sergei D.
2010-09-01
We study scalar-tensor theory, k-essence and modified gravity with Lagrange multiplier constraint which role is to reduce the number of degrees of freedom. Dark Energy cosmology of different types (ΛCDM, unified inflation with DE, smooth non-phantom/phantom transition epoch) is reconstructed in such models. It is demonstrated that presence of Lagrange multiplier simplifies the reconstruction scenario. It is shown that mathematical equivalence between scalar theory and F(R) gravity is broken due to presence of constraint. The cosmological evolution is defined by the second F(R) function dictated by the constraint. The convenient F(R) gravity sector is relevant for local tests. This opens the possibility to make originally non-realistic theory to be viable by adding the corresponding constraint. A general discussion on the role of Lagrange multipliers to make higher-derivative gravity canonical is developed.
Visualizing and Understanding the Components of Lagrange and Newton Interpolation
ERIC Educational Resources Information Center
Yang, Yajun; Gordon, Sheldon P.
2016-01-01
This article takes a close look at Lagrange and Newton interpolation by graphically examining the component functions of each of these formulas. Although interpolation methods are often considered simply to be computational procedures, we demonstrate how the components of the polynomial terms in these formulas provide insight into where these…
"Lagrange functions" for order(N) electronic structure calculations
NASA Astrophysics Data System (ADS)
Varga, Kalman; Zhang, Zhenyu; Pantelides, S. T.
2004-03-01
"Plane waves" have several highly desirable properties for electronic structure calculations, but effectively scale as N3, where N is the number of atoms, because they impose a uniform grid on which one must perform fast Fourier transforms (FFTs). To achieve near-order-N methods, it is imperative to adopt "real-space methods and non-uniform grids. The objective is usually pursued either by discretization or by adopting local basis sets, either numerical or analytical, with optimized short range. Here we report on a novel basis set, which we label "Lagrange functions" that are defined to satisfy the Lagrange interpolation condition and on a grid that corresponds to a Gaussian quadrature for integrations with optimized numerical accuracy. Lagrange functions combine the best attributes of plane waves and real-space methods. Just like plane waves, convergence is controlled by a single parameter in a systematic way, are orthonormal and defined analytically everywhere, but have the added flexibility of a weight function that controls the distribution of grid points and can be used to optimize the calculation for each system. They do not require FFTs and integrals are trivial and accurate since each Lagrange function is nonzero on a single grid point. The power of the method will be illustrated with several examples.
Accurate solution of the Dirac equation on Lagrange meshes.
Baye, Daniel; Filippin, Livio; Godefroid, Michel
2014-04-01
The Lagrange-mesh method is an approximate variational method taking the form of equations on a grid because of the use of a Gauss quadrature approximation. With a basis of Lagrange functions involving associated Laguerre polynomials related to the Gauss quadrature, the method is applied to the Dirac equation. The potential may possess a 1/r singularity. For hydrogenic atoms, numerically exact energies and wave functions are obtained with small numbers n+1 of mesh points, where n is the principal quantum number. Numerically exact mean values of powers -2 to 3 of the radial coordinate r can also be obtained with n+2 mesh points. For the Yukawa potential, a 15-digit agreement with benchmark energies of the literature is obtained with 50 or fewer mesh points. PMID:24827362
Implicit Lagrange-Routh equations and Dirac reduction
NASA Astrophysics Data System (ADS)
García-Toraño Andrés, Eduardo; Mestdag, Tom; Yoshimura, Hiroaki
2016-06-01
In this paper, we make a generalization of Routh's reduction method for Lagrangian systems with symmetry to the case where not any regularity condition is imposed on the Lagrangian. First, we show how implicit Lagrange-Routh equations can be obtained from the Hamilton-Pontryagin principle, by making use of an anholonomic frame, and how these equations can be reduced. To do this, we keep the momentum constraint implicit throughout and we make use of a Routhian function defined on a certain submanifold of the Pontryagin bundle. Then, we show how the reduced implicit Lagrange-Routh equations can be described in the context of dynamical systems associated to Dirac structures, in which we fully utilize a symmetry reduction procedure for implicit Hamiltonian systems with symmetry.
Accurate solution of the Dirac equation on Lagrange meshes
NASA Astrophysics Data System (ADS)
Baye, Daniel; Filippin, Livio; Godefroid, Michel
2014-04-01
The Lagrange-mesh method is an approximate variational method taking the form of equations on a grid because of the use of a Gauss quadrature approximation. With a basis of Lagrange functions involving associated Laguerre polynomials related to the Gauss quadrature, the method is applied to the Dirac equation. The potential may possess a 1/r singularity. For hydrogenic atoms, numerically exact energies and wave functions are obtained with small numbers n +1 of mesh points, where n is the principal quantum number. Numerically exact mean values of powers -2 to 3 of the radial coordinate r can also be obtained with n +2 mesh points. For the Yukawa potential, a 15-digit agreement with benchmark energies of the literature is obtained with 50 or fewer mesh points.
Simultaneous least squares fitter based on the Lagrange multiplier method
NASA Astrophysics Data System (ADS)
Guan, Ying-Hui; Lü, Xiao-Rui; Zheng, Yang-Heng; Zhu, Yong-Sheng
2013-10-01
We developed a least squares fitter used for extracting expected physics parameters from the correlated experimental data in high energy physics. This fitter considers the correlations among the observables and handles the nonlinearity using linearization during the χ2 minimization. This method can naturally be extended to the analysis with external inputs. By incorporating with Lagrange multipliers, the fitter includes constraints among the measured observables and the parameters of interest. We applied this fitter to the study of the D0-D¯0 mixing parameters as the test-bed based on MC simulation. The test results show that the fitter gives unbiased estimators with correct uncertainties and the approach is credible.
Euler-Lagrange formulas for pseudo-Kähler manifolds
NASA Astrophysics Data System (ADS)
Park, JeongHyeong
2016-01-01
Let c be a characteristic form of degree k which is defined on a Kähler manifold of real dimension m > 2 k. Taking the inner product with the Kähler form Ωk gives a scalar invariant which can be considered as a generalized Lovelock functional. The associated Euler-Lagrange equations are a generalized Einstein-Gauss-Bonnet gravity theory; this theory restricts to the canonical formalism if c =c2 is the second Chern form. We extend previous work studying these equations from the Kähler to the pseudo-Kähler setting.
Convergence of a Substructuring Method with LaGrange Multipliers
NASA Technical Reports Server (NTRS)
Mandel, Jan; Tezaur, Radek
1996-01-01
We analyze the convergence of a substructuring iterative method with Lagrange multipliers, proposed recently by Farhat and Roux. The method decomposes finite element discretization of an elliptic boundary value problem into Neumann problems on the subdomains and a coarse problem for the subdomain nullspace components. For linear conforming elements and preconditioning by the Dirichlet problems on the subdomains, we prove the asymptotic bound on the condition number C(1 + log(H/h))(sup gamma), gamma = 2 or 3, where h is the characteristic element size and H is the subdomain size.
Two Lagrange-like optical invariants and some applications.
Corrente, Fabio; Onorato, Pasquale
2011-05-01
Geometric optics can be completely derived from Fermat's principle, as classical mechanics can be obtained by the application of the Hamilton principle. In Lagrangian optics, for optical systems with rotational symmetry, is known the invariant L₃, the Lagrange optical invariant. For systems built only with spherical lenses, we demonstrate there are two other optical invariants, L₁ and L₂, analogous to L₃. A proof based on Snell's law, the Weierstrass-Erdman jump condition, and the expression of the ray between two optical surfaces in the Hamiltonian formalism is reported. The presence of a conserved vector, L, allows us to write the equation of an emerging ray without any approximation. PMID:21540974
ERIC Educational Resources Information Center
Sartorius, Tara Cady
2010-01-01
Many artists visit national parks to draw, paint and take photographs of some of the most amazing scenery on earth. Raw nature is one of the greatest inspirations to an artist, and artists can be credited for helping inspire the government to create the National Park System. This article features Thomas Moran (1837-1926), one of the artists who…
Interferometric Characterization of the Earth's Atmosphere from Lagrange Point 2
NASA Technical Reports Server (NTRS)
Herman, J. R.; Einaudi, Franco (Technical Monitor)
2001-01-01
Part of the NASA plans for future Earth-Science missions calls for observations using novel vantage points that can produce science products otherwise unobtainable. Observations of the Earth from the Lagrange-2 point, L-2, (1.5 million kilometers behind the Earth on the Earth-Sun line) affords a unique vantage point for atmospheric science. Special observation of the Earth's atmosphere using solar occultation techniques in the near infrared (1 to 4 microns) provides one of the most accurate method of passively sensing altitude profiles of the major species (CO2, O3, O2, CH4, H2O, N2O). In addition to observation of the Earth's atmosphere, it will be possible to observe a portion of the solar disk at moderate spatial resolution without interference from the Earth.
Spectral distributed Lagrange multiplier method: algorithm and benchmark tests
NASA Astrophysics Data System (ADS)
Dong, Suchuan; Liu, Dong; Maxey, Martin R.; Karniadakis, George Em
2004-04-01
We extend the formulation of the distributed Lagrange multiplier (DLM) approach for particulate flows to high-order methods within the spectral/ hp element framework. We implement the rigid-body motion constraint inside the particle via a penalty method. The high-order DLM method demonstrates spectral convergence rate, i.e. discretization errors decrease exponentially as the order of spectral polynomials increases. We provide detailed comparisons between the spectral DLM method, direct numerical simulations, and the force coupling method for a number of 2D and 3D benchmark flow problems. We also validate the spectral DLM method with available experimental data for a transient problem. The new DLM method can potentially be very effective in many-moving body problems, where a smaller number of grid points is required in comparison with low-order methods.
LAGRANGE: LAser GRavitational-wave ANtenna in GEodetic Orbit
NASA Astrophysics Data System (ADS)
Buchman, S.; Conklin, J. W.; Balakrishnan, K.; Aguero, V.; Alfauwaz, A.; Aljadaan, A.; Almajed, M.; Altwaijry, H.; Saud, T. A.; Byer, R. L.; Bower, K.; Costello, B.; Cutler, G. D.; DeBra, D. B.; Faied, D. M.; Foster, C.; Genova, A. L.; Hanson, J.; Hooper, K.; Hultgren, E.; Klavins, A.; Lantz, B.; Lipa, J. A.; Palmer, A.; Plante, B.; Sanchez, H. S.; Saraf, S.; Schaechter, D.; Shu, K.; Smith, E.; Tenerelli, D.; Vanbezooijen, R.; Vasudevan, G.; Williams, S. D.; Worden, S. P.; Zhou, J.; Zoellner, A.
2013-01-01
We describe a new space gravitational wave observatory design called LAG-RANGE that maintains all important LISA science at about half the cost and with reduced technical risk. It consists of three drag-free spacecraft in a geocentric formation. Fixed antennas allow continuous contact with the Earth, solving the problem of communications bandwidth and latency. A 70 mm diameter sphere with a 35 mm gap to its enclosure serves as the single inertial reference per spacecraft, operating in “true” drag-free mode (no test mass forcing). Other advantages are: a simple caging design based on the DISCOS 1972 drag-free mission, an all optical read-out with pm fine and nm coarse sensors, and the extensive technology heritage from the Honeywell gyroscopes, and the DISCOS and Gravity Probe B drag-free sensors. An Interferometric Measurement System, designed with reflective optics and a highly stabilized frequency standard, performs the ranging between test masses and requires a single optical bench with one laser per spacecraft. Two 20 cm diameter telescopes per spacecraft, each with infield pointing, incorporate novel technology developed for advanced optical systems by Lockheed Martin, who also designed the spacecraft based on a multi-flight proven bus structure. Additional technological advancements include updated drag-free propulsion, thermal control, charge management systems, and materials. LAGRANGE subsystems are designed to be scalable and modular, making them interchangeable with those of LISA or other gravitational science missions. We plan to space qualify critical technologies on small and nano satellite flights, with the first launch (UV-LED Sat) in 2013.
Interferometric Characterization of the Earth's Atmosphere from Lagrange Point 2
NASA Technical Reports Server (NTRS)
Herman, Jay R.; Komar, George (Technical Monitor)
2001-01-01
Part of the NASA plans for future Earth Science missions calls for observations using novel vantage points that can produce science products otherwise unobtainable. Observations of the Earth from the Lagrange-2 point, L-2, (1.5 million km behind the Earth on the Earth-Sun line) affords a unique vantage point for atmospheric science. Spectral observation of the Earth's atmosphere using solar occultation techniques in the near infrared (1 to 4 microns) provides one of the most accurate methods of passively sensing attitude profiles of the major species (CO2, O3, O2, CH4, H2O N2O). While traditional polar orbiting occultation measurements can obtain about 14 measurements per day (2 per orbit), solar occultation observations from the Lagrange-2 point will yield hourly profile measurements at all latitudes. The expected spatial resolution is 2 km in altitude, 0.5 degrees in latitude, and 2 degrees in longitude. The result from 24 hours of observations will be a three-dimensional map of atmospheric composition. To accomplish this task from L-2 requires the development of a large moderate spectral resolution instrument whose entrance aperture is about 10 meters. Use of a standard telescope design with a 10-meter circular mirror or a 10-meter strip mirror would be prohibitively expensive and excessively massive. Instead, we are proposing the development of a 10-meter linear interferometer coupled to a Fourier transform imaging spectrometer. The result will be a highly efficient design with sufficient sensitivity, while having both spatial and spectral resolution to produce the desired results. Preliminary calculations show that seven species (CO2, O3, O2, CH4, H2O N2O) have clearly separated spectral features in the I to 4 microns range with sufficient absorption to produce profile information from near the Earth's surface to the middle stratosphere. For CO2 the estimated sensitivity to change is 0.33% or 1 part in 330. This should be sufficient to detect changes that are
What Did We Think Could Be Learned About Earth From Lagrange Point Observations?
NASA Technical Reports Server (NTRS)
Wiscombe, Warren
2011-01-01
The scientific excitement surrounding the NASA Lagrange point mission Triana, now called DSCOVR, tended to be forgotten in the brouhaha over other aspects of the mission. Yet a small band of scientists in 1998 got very excited about the possibilities offered by the Lagrange-point perspective on our planet. As one of the original co-investigators on the Triana mission, I witnessed that scientific excitement firsthand. I will bring to life the early period, circa 1998 to 2000, and share the reasons that we thought the Lagrange-point perspective on Earth would be scientifically revolutionary.
NASA Technical Reports Server (NTRS)
1999-01-01
The Parking Garage Automation System (PGAS) is based on a technology developed by a NASA-sponsored project called Robot sensorSkin(TM). Merritt Systems, Inc., of Orlando, Florida, teamed up with NASA to improve robots working with critical flight hardware at Kennedy Space Center in Florida. The system, containing smart sensor modules and flexible printed circuit board skin, help robots to steer clear of obstacles using a proximity sensing system. Advancements in the sensor designs are being applied to various commercial applications, including the PGAS. The system includes a smartSensor(TM) network installed around and within public parking garages to autonomously guide motorists to open facilities, and once within, to free parking spaces. The sensors use non-invasive reflective-ultrasonic technology for high accuracy, high reliability, and low maintenance. The system is remotely programmable: it can be tuned to site-specific requirements, has variable range capability, and allows remote configuration, monitoring, and diagnostics. The sensors are immune to interference from metallic construction materials, such as rebar and steel beams. Inside the garage, smart routing signs mounted overhead or on poles in front of each row of parking spots guide the motorist precisely to free spaces.
Control of Lagrange point orbits using solar sail propulsion
NASA Astrophysics Data System (ADS)
Bookless, John; McInnes, Colin
2008-01-01
Several missions have utilised halo orbits around the L1 and L2 Lagrange points of the Earth-Sun system. Due to the instability of these orbits, station-keeping techniques are required to prevent escape after orbit insertion. This paper considers using solar sail propulsion to provide station-keeping at quasi-periodic orbits around L1 and L2. Stable manifolds will be identified which provide near-Earth insertion to a quasi-periodic trajectory around the libration point. The possible control techniques investigated include solar sail area variation and solar sail pitch and yaw angle variation. Hill's equations are used to model the dynamics of the problem and optimal control laws are developed to minimise the control requirements. The constant thrust available using solar sails can be used to generate artificial libration points Sunwards of L1 or Earthwards of L2. A possible mission to position a science payload Sunward of L1 will be investigated. After insertion to a halo orbit at L1, gradual solar sail deployment can be performed to spiral Sunwards along the Sun-Earth axis. Insertion ΔV requirements and area variation control requirements will be examined. This mission could provide advance warning of Earthbound coronal mass ejections (CMEs) responsible for magnetic storms.
Lagrange and average interpolation over 3D anisotropic elements
NASA Astrophysics Data System (ADS)
Acosta, Gabriel
2001-10-01
An average interpolation is introduced for 3-rectangles and tetrahedra, and optimal order error estimates in the H1 norm are proved. The constant in the estimate depends "weakly" (improving the results given in Durán (Math. Comp. 68 (1999) 187-199) on the uniformity of the mesh in each direction. For tetrahedra, the constant also depends on the maximum angle of the element. On the other hand, merging several known results (Acosta and Durán, SIAM J. Numer. Anal. 37 (1999) 18-36; Durán, Math. Comp. 68 (1999) 187-199; Krízek, SIAM J. Numer. Anal. 29 (1992) 513-520; Al Shenk, Math. Comp. 63 (1994) 105-119), we prove optimal order error for the -Lagrange interpolation in W1,p, p>2, with a constant depending on p as well as the maximum angle of the element. Again, under the maximum angle condition, optimal order error estimates are obtained in the H1 norm for higher degree interpolations.
Centrifuge Rotor Models: A Comparison of the Euler-Lagrange and the Bond Graph Modeling Approach
NASA Technical Reports Server (NTRS)
Granda, Jose J.; Ramakrishnan, Jayant; Nguyen, Louis H.
2006-01-01
A viewgraph presentation on centrifuge rotor models with a comparison using Euler-Lagrange and bond graph methods is shown. The topics include: 1) Objectives; 2) MOdeling Approach Comparisons; 3) Model Structures; and 4) Application.
15. City parking lot, and rear of the commercial buildings ...
15. City parking lot, and rear of the commercial buildings on the east side of State Street. - Lockport Historic District, Bounded by Eighth, Hamilton & Eleventh Streets & Illinois & Michigan Canal, Lockport, Will County, IL
National Environmental Research Parks
Not Available
1994-07-01
The National Environmental Research Parks are outdoor laboratories that provide opportunities for environmental studies on protected lands that act as buffers around Department of Energy (DOE) facilities. The research parks are used to evaluate the environmental consequences of energy use and development as well as the strategies to mitigate these effects. They are also used to demonstrate possible environmental and land-use options. The seven parks are: Fermilab National Environmental Research Park; Hanford National Environmental Research Park; Idaho National Environmental Research Park; Los Alamos National Environmental Research Park; Nevada National Environmental Research Park; Oak Ridge National Environmental Research Park; and Savannah River National Environmental Research Park. This document gives an overview of the events that led to the creation of the research parks. Its main purpose is to summarize key points about each park, including ecological research, geological characteristics, facilities, and available databases.
NASA Astrophysics Data System (ADS)
Sharifi, M. A.; Seif, M. R.
2011-09-01
The analytical methods have nearly been replaced by the numerical methods due to their higher accuracy and accessibility of computation facilities. The semi-analytical Lagrange method of orbit propagation using f and g series is a competitive alternative to the numerical integration technique if the Lagrange coefficients are derived in a full gravitational field. In this paper, a generalization of the Lagrange method of orbit propagation is introduced. In other words, we introduce a complete form of the Lagrange coefficients in all force fields developed in the spherical harmonics for example full gravitational field of the Earth. The method is numerically compared with the numerical integration technique. In order to show the numerical performance of the method, it has been implemented for orbit propagation of a GPS-like MEO and CHAMP-like LEO satellites. Discrepancy at centimeter level for CHAMP-like and sub-millimeter accuracy for GPS-like satellites shows relatively high performance of the developed algorithm. Compared to integration method, the proposed Lagrange method is nearly faster by a factor two for small Nmax and four for large Nmax.
Comparison of Direct Eulerian Godunov and Lagrange Plus Remap, Artificial Viscosity Schemes
Pember, R B; Anderson, R W
2001-03-30
The authors compare two algorithms for solving the equations of unsteady inviscid compressible flow in an Eulerian frame: a staggered grid, Lagrange plus remap artificial viscosity scheme and a cell-centered, direct Eulerian higher-order Godunov scheme. They use the two methods to compute solutions to a number of one- and two-dimensional problems. The results show the accuracy of the two schemes to be generally equivalent. In a 1984 survey paper by Woodward and Colella, the Lagrange plus remap approach did not compare favorably with the higher-order Godunov methodology. They examine, therefore, how certain features of the staggered grid scheme considered here contribute to its improved accuracy. The critical features are shown to be the use of a monotonic artificial viscosity in the Lagrange step and, in the remap step, the use of a corner transport upwind scheme with van Leer limiters in conjunction with separate advection of internal and kinetic energies.
NASA Technical Reports Server (NTRS)
Watts, G.
1992-01-01
A programming technique to eliminate computational instability in multibody simulations that use the Lagrange multiplier is presented. The computational instability occurs when the attached bodies drift apart and violate the constraints. The programming technique uses the constraint equation, instead of integration, to determine the coordinates that are not independent. Although the equations of motion are unchanged, a complete derivation of the incorporation of the Lagrange multiplier into the equation of motion for two bodies is presented. A listing of a digital computer program which uses the programming technique to eliminate computational instability is also presented. The computer program simulates a solid rocket booster and parachute connected by a frictionless swivel.
A Lagrange-Galerkin hp-Finite Element Method for a 3D Nonhydrostatic Ocean Model
NASA Astrophysics Data System (ADS)
Galán del Sastre, Pedro; Bermejo, Rodolfo
2016-03-01
We introduce in this paper a Lagrange-Galerkin hp-finite element method to calculate the numerical solution of a nonhydrostatic ocean model. The Lagrange-Galerkin method yields a Stokes-like problem the solution of which is computed by a second-order rotational splitting scheme that separates the calculation of the velocity and pressure, the latter is decomposed into hydrostatic and nonhydrostatic components. We have tested the method in flows where the nonhydrostatic effects are important. The results are very encouraging.
Neves, Fabiana; Abrantes, Joana; Almeida, Tereza; de Matos, Ana Lemos; Costa, Paulo P
2015-01-01
ILs, as essential innate immune modulators, are involved in an array of biological processes. In the European rabbit (Oryctolagus cuniculus) IL-1α, IL-1β, IL-2, IL-4, IL-8, IL-10, IL-12A, IL-12B, IL-15 and IL-18 have been implicated in inflammatory processes and in the immune response against rabbit hemorrhagic disease virus and myxoma virus infections. In this study we characterized these ILs in six Lagomorpha species (European rabbit, pygmy rabbit, two cottontail rabbit species, European brown hare and American pika). Overall, these ILs are conserved between lagomorphs, including in their exon/intron structure. Most differences were observed between leporids and American pika. Indeed, when comparing both, some relevant differences were observed in American pika, such as the location of the stop codon in IL-1α and IL-2, the existence of a different transcript in IL8 and the number of cysteine residues in IL-1β. Changes at N-glycosylation motifs were also detected in IL-1, IL-10, IL-12B and IL-15. IL-1α is the protein that presents the highest evolutionary distances, which is in contrast to IL-12A where the distances between lagomorphs are the lowest. For all these ILs, sequences of human and European rabbit are more closely related than between human and mouse or European rabbit and mouse. PMID:26395994
Neves, Fabiana; Abrantes, Joana; Almeida, Tereza; de Matos, Ana Lemos; Costa, Paulo P; Esteves, Pedro J
2015-11-01
ILs, as essential innate immune modulators, are involved in an array of biological processes. In the European rabbit (Oryctolagus cuniculus) IL-1α, IL-1β, IL-2, IL-4, IL-8, IL-10, IL-12A, IL-12B, IL-15 and IL-18 have been implicated in inflammatory processes and in the immune response against rabbit hemorrhagic disease virus and myxoma virus infections. In this study we characterized these ILs in six Lagomorpha species (European rabbit, pygmy rabbit, two cottontail rabbit species, European brown hare and American pika). Overall, these ILs are conserved between lagomorphs, including in their exon/intron structure. Most differences were observed between leporids and American pika. Indeed, when comparing both, some relevant differences were observed in American pika, such as the location of the stop codon in IL-1α and IL-2, the existence of a different transcript in IL8 and the number of cysteine residues in IL-1β. Changes at N-glycosylation motifs were also detected in IL-1, IL-10, IL-12B and IL-15. IL-1α is the protein that presents the highest evolutionary distances, which is in contrast to IL-12A where the distances between lagomorphs are the lowest. For all these ILs, sequences of human and European rabbit are more closely related than between human and mouse or European rabbit and mouse. PMID:26395994
Resolution of the Gross-Pitaevskii equation with the imaginary-time method on a Lagrange mesh.
Baye, D; Sparenberg, J-M
2010-11-01
The Lagrange-mesh method is an approximate variational calculation which has the simplicity of a mesh calculation. Combined with the imaginary-time method, it is applied to the iterative resolution of the Gross-Pitaevskii equation. Two variants of a fourth-order factorization of the exponential of the Hamiltonian and two types of mesh (Lagrange-Hermite and Lagrange-sinc) are employed and compared. The accuracy is checked with the help of these comparisons and of the virial theorem. The Lagrange-Hermite mesh provides very accurate results with short computing times for values of the dimensionless parameter of the nonlinear term up to 10⁴. For higher values up to 10⁷, the Lagrange-sinc mesh is more efficient. Examples are given for anisotropic and nonseparable trapping potentials. PMID:21230613
Necessary conditions for weighted mean convergence of Lagrange interpolation for exponential weights
NASA Astrophysics Data System (ADS)
Damelin, S. B.; Jung, H. S.; Kwon, K. H.
2001-07-01
Given a continuous real-valued function f which vanishes outside a fixed finite interval, we establish necessary conditions for weighted mean convergence of Lagrange interpolation for a general class of even weights w which are of exponential decay on the real line or at the endpoints of (-1,1).
Pointwise convergence of derivatives of Lagrange interpolation polynomials for exponential weights
NASA Astrophysics Data System (ADS)
Damelin, S. B.; Jung, H. S.
2005-01-01
For a general class of exponential weights on the line and on (-1,1), we study pointwise convergence of the derivatives of Lagrange interpolation. Our weights include even weights of smooth polynomial decay near +/-[infinity] (Freud weights), even weights of faster than smooth polynomial decay near +/-[infinity] (Erdos weights) and even weights which vanish strongly near +/-1, for example Pollaczek type weights.
1. Mill village dwelling at 817 Forest St. in LaGrange. ...
1. Mill village dwelling at 817 Forest St. in LaGrange. Note the hipped roof and wrap-around porch with heavy cornice and Doric columns. The quality of decorative detail here suggests that this house would have been for a mill manager. - 817 Forest Street (House), 817 Forest Street, La Grange, Troup County, GA
Frequency nondegeneracy of the Lagrange gyroscope and a balanced gyroscope with a gimbal suspension
NASA Astrophysics Data System (ADS)
Tatarinov, Ia. V.
1987-08-01
The three-frequency nature of the motion of a specific Lagrange gyroscope (whose center of mass does not coincide with the suspension point) and a specific gimbal-mounted gyroscope is demonstrated. The proof presented here is based on frequency expansions near stable relative equilibriums (regular precessions).
NASA Technical Reports Server (NTRS)
2002-01-01
Thirteen years after devastating forest fires burned over 1.6 million acres in Yellowstone National Park, the scars are still evident. In this simulated natural color ASTER image, burned areas appear gray, in contrast to the dark green of unburned forests. The image covers an area of 60 x 63 km. This image was acquired on July 2, 2001 by the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) on NASA's Terra satellite. With its 14 spectral bands from the visible to the thermal infrared wavelength region, and its high spatial resolution of 15 to 90 meters (about 50 to 300 feet), ASTER images Earth to map and monitor the changing surface of our planet.
ASTER is one of five Earth-observing instruments launched December 18, 1999, on NASA's Terra satellite. The instrument was built by Japan's Ministry of Economy, Trade and Industry. A joint U.S./Japan science team is responsible for validation and calibration of the instrument and the data products.
The broad spectral coverage and high spectral resolution of ASTER will provide scientists in numerous disciplines with critical information for surface mapping, and monitoring of dynamic conditions and temporal change. Example applications are: monitoring glacial advances and retreats; monitoring potentially active volcanoes; identifying crop stress; determining cloud morphology and physical properties; wetlands evaluation; thermal pollution monitoring; coral reef degradation; surface temperature mapping of soils and geology; and measuring surface heat balance.
Dr. Anne Kahle at NASA's Jet Propulsion Laboratory, Pasadena, California, is the U.S. Science team leader; Bjorn Eng of JPL is the project manager. The Terra mission is part of NASA's Earth Science Enterprise, a long- term research effort to understand and protect our home planet. Through the study of Earth, NASA will help to provide sound science to policy and economic decision-makers so as to better life here, while developing the
Atmospheric Science Data Center
2013-04-15
... images of northeastern South Africa, near Kruger National Park, were acquired on September 7, 2000. The left image shows an 85-kilometer ... Sep 7, 2000 Images: Kruger Park location: Africa thumbnail: ...
Rosen, Joseph; Kelner, Roy
2014-01-01
The Lagrange invariant is a well-known law for optical imaging systems formulated in the frame of ray optics. In this study, we reformulate this law in terms of wave optics and relate it to the resolution limits of various imaging systems. Furthermore, this modified Lagrange invariant is generalized for imaging along the z axis, resulting with the axial Lagrange invariant which can be used to analyze the axial resolution of various imaging systems. To demonstrate the effectiveness of the theory, analysis of the lateral and the axial imaging resolutions is provided for Fresnel incoherent correlation holography (FINCH) systems. PMID:25402144
The National Park Service has produced a data base of boundaries for its National Parks. A copy of this data was downloaded from the National Parks Service ftp site by Region 10. These digital boundaries represent the best guess and data that could be collected in a short time....
PARKING PROGRAMS FOR UNIVERSITIES.
ERIC Educational Resources Information Center
KINNE, W.S., JR.
PARKING FACILITIES WERE SURVEYED AT 83 REPRESENTATIVE UNIVERSITIES AND COLLEGES, AND THE METHODS USED IN ADMINISTERING, CONTROLLING AND FINANCING WERE EVALUTED. GENERAL RECOMMENDATIONS WERE MADE CONCERNING (1) THE LOCATION AND DESIGN OF PARKING LOTS AND GARAGES, (2) THE PRACTICE OF CURB PARKING ON CAMPUS, AND (3) THE FINANCING OF PARKING…
ERIC Educational Resources Information Center
Bowman, Sally-Jo
1998-01-01
More than 50 National Park Service (NPS) sites interpret Native cultures or early Native contact with Europeans. In about 30 of those, American Indians, Alaska Natives, or Native Hawaiians, in partnership with the NPS, present their own heritage and issues. Describes Native-run aspects of Sitka National Historical Park, Glacier National Park, and…
ERIC Educational Resources Information Center
Ormrod, Richard K.
1984-01-01
To utilize park facilities to their fullest, visitors must be well-oriented to the park's physical layout. The results of a study undertaken at Rocky Mountain National Park indicate that information should be readily accessible and easy to use. (DF)
Dual mixed finite element methods for the elasticity problem with Lagrange multipliers
NASA Astrophysics Data System (ADS)
Boulaajine, L.; Nicaise, S.; Paquet, L.; Rafilipojaona
2008-11-01
We study a dual mixed formulation of the elasticity system in a polygonal domain of the plane with mixed boundary conditions and its numerical approximation. The (essential) Neumann boundary conditions (or traction boundary condition) are imposed using a discontinuous Lagrange multiplier corresponding to the trace of the displacement field. Moreover, a strain tensor is introduced as a new unknown and its symmetry is relaxed, also by the use of a Lagrange multiplier (the rotation). The singular behaviour of the solution requires us to use refined meshes to restore optimal rates of convergence. Uniform error estimates in the Lamé coefficient [lambda] are obtained for large [lambda]. The hybridization of the problem is performed and numerical tests are presented confirming our theoretical results.
Application of the Euler-Lagrange method in determination of the coordinate acceleration
NASA Astrophysics Data System (ADS)
Sfarti, A.
2016-05-01
In a recent comment published in this journal (2015 Eur. J. Phys. 36 038001), Khrapko derived the relationship between coordinate acceleration and coordinate speed for the case of radial motion in Schwarzschild coordinates. We will show an alternative derivation based on the Euler-Lagrange formalism. The Euler-Lagrange formalism has the advantage that it circumvents the tedious calculations of the Christoffel symbols and it is more intuitive. Another aspect of our comment is that one should not give much physical meaning to coordinate dependent entities, GR is a coordinate free field, so, a relationship between two coordinate dependent entities, like the acceleration being dependent on speed, should not be given much importance. By contrast, the proper acceleration and proper speed, are meaningful entities and their relationship is relevant. The comment is intended for graduate students and for the instructors who teach GR.
Lagrange-Function Approach to Real-Space Order-N Electronic-Structure Calculations
Varga, Kalman; Pantelides, Sokrates T
2006-01-01
The Lagrange functions are a family of analytical, complete, and orthonormal basis sets that are suitable for efficient, accurate, real-space, order-N electronic-structure calculations. Convergence is controlled by a single monotonic parameter, the dimension of the basis set, and computational complexity is lower than that of conventional approaches. In this paper we review their construction and applications in linearscaling electronic-structure calculations.
FLAG: A multi-dimensional adaptive free-Lagrange code for fully unstructured grids
Burton, D.E.; Miller, D.S.; Palmer, T.
1995-07-01
The authors describe FLAG, a 3D adaptive free-Lagrange method for unstructured grids. The grid elements were 3D polygons, which move with the flow, and are refined or reconnected as necessary to achieve uniform accuracy. The authors stressed that they were able to construct a 3D hydro version of this code in 3 months, using an object-oriented FORTRAN approach.
Rabl, P.F.H.; Euskirchen, J.
1996-10-01
During the last decade hydrogen ballooning provided a reliable basis for special airborne measurements especially for experiments that give evidence about atmospheric chemistry and structure. Although the balloon is not quite a small particle without inertia, Lagrange-like movements of atmospheric mass can be simulated. During two experiments, the vertical gradients of ozone concentration were measured in the downwind area of Munich. The results show remarkable differences in ozone concentration and production, dependent of the daytime. 3 refs., 3 figs.
On the connection between Hamilton and Lagrange formalism in quantum field theory
NASA Astrophysics Data System (ADS)
Villalba-Chávez, Selym; Alkofer, Reinhard; Schwenzer, Kai
2010-08-01
The connection between the Hamilton and the standard Lagrange formalism is established for a generic quantum field theory with vanishing vacuum expectation values of the fundamental fields. The effective actions in both formalisms are the same if and only if the fundamental fields and the momentum fields are related by the stationarity condition. These momentum fields in general differ from the canonical fields as defined via the effective action. By means of functional methods a systematic procedure is presented to identify the full correlation functions, which depend on the momentum fields, as functionals of those usually appearing in the standard Lagrange formalism. Whereas Lagrange correlation functions can be decomposed into tree diagrams, the decomposition of Hamilton correlation functions involves loop corrections similar to those arising in n-particle effective actions. To demonstrate the method we derive for theories with linearized interactions the propagators of composite auxiliary fields and the ones of the fundamental degrees of freedom. The formalism is then utilized in the case of Coulomb gauge Yang-Mills theory for which the relations between the two-point correlation functions of the transversal and longitudinal components of the conjugate momentum to the ones of the gauge field are given.
NASA Astrophysics Data System (ADS)
Rivera, Christian A.; Heniche, Mourad; Glowinski, Roland; Tanguy, Philippe A.
2010-07-01
A parallel approach to solve three-dimensional viscous incompressible fluid flow problems using discontinuous pressure finite elements and a Lagrange multiplier technique is presented. The strategy is based on non-overlapping domain decomposition methods, and Lagrange multipliers are used to enforce continuity at the boundaries between subdomains. The novelty of the work is the coupled approach for solving the velocity-pressure-Lagrange multiplier algebraic system of the discrete Navier-Stokes equations by a distributed memory parallel ILU (0) preconditioned Krylov method. A penalty function on the interface constraints equations is introduced to avoid the failure of the ILU factorization algorithm. To ensure portability of the code, a message based memory distributed model with MPI is employed. The method has been tested over different benchmark cases such as the lid-driven cavity and pipe flow with unstructured tetrahedral grids. It is found that the partition algorithm and the order of the physical variables are central to parallelization performance. A speed-up in the range of 5-13 is obtained with 16 processors. Finally, the algorithm is tested over an industrial case using up to 128 processors. In considering the literature, the obtained speed-ups on distributed and shared memory computers are found very competitive.
76 FR 80393 - Notice of Inventory Completion: Field Museum of Natural History, Chicago, IL
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-23
... National Park Service Notice of Inventory Completion: Field Museum of Natural History, Chicago, IL AGENCY: National Park Service, Interior. ACTION: Notice. SUMMARY: The Field Museum of Natural History has completed... Field Museum of Natural History. Repatriation of the human remains and associated funerary objects...
Parks, Recreation and Public Health.
ERIC Educational Resources Information Center
Ho, Ching-Hua; Payne, Laura; Orsega-Smith, Elizabeth; Godbey, Geoffrey
2003-01-01
Reviews what current research says about the holistic health benefits of park and recreation services, focusing on: health benefits according to park users; physical activities in parks; stress reduction benefits of park use; social support, self-determination, and stress reduction; observing nature in parks and associated benefits; and the…
78 FR 55219 - Safety Zone; Flying Machine Competition, Chicago, IL
Federal Register 2010, 2011, 2012, 2013, 2014
2013-09-10
... FR Federal Register NPRM Notice of Proposed Rulemaking TFR Temporary Final Rule A. Regulatory History... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Flying Machine Competition, Chicago, IL... zone is intended to restrict vessels from a portion of Lake Michigan near Burnham Park during a...
Investigating Trojan Asteroids at the L4/L5 Sun-Earth Lagrange Points
NASA Technical Reports Server (NTRS)
John, K. K.; Graham, L. D.; Abell, P. A.
2015-01-01
Investigations of Earth's Trojan asteroids will have benefits for science, exploration, and resource utilization. By sending a small spacecraft to the Sun-Earth L4 or L5 Lagrange points to investigate near-Earth objects, Earth's Trojan population can be better understood. This could lead to future missions for larger precursor spacecraft as well as human missions. The presence of objects in the Sun-Earth L4 and L5 Lagrange points has long been suspected, and in 2010 NASA's Wide-field Infrared Survey Explorer (WISE) detected a 300 m object. To investigate these Earth Trojan asteroid objects, it is both essential and feasible to send spacecraft to these regions. By exploring a wide field area, a small spacecraft equipped with an IR camera could hunt for Trojan asteroids and other Earth co-orbiting objects at the L4 or L5 Lagrange points in the near-term. By surveying the region, a zeroth-order approximation of the number of objects could be obtained with some rough constraints on their diameters, which may lead to the identification of potential candidates for further study. This would serve as a precursor for additional future robotic and human exploration targets. Depending on the inclination of these potential objects, they could be used as proving areas for future missions in the sense that the delta-V's to get to these targets are relatively low as compared to other rendezvous missions. They can serve as platforms for extended operations in deep space while interacting with a natural object in microgravity. Theoretically, such low inclination Earth Trojan asteroids exist. By sending a spacecraft to L4 or L5, these likely and potentially accessible targets could be identified.
5. VIEW OF NORTH PARK AVENUE TRAILHEAD PARKING AREA FACING ...
5. VIEW OF NORTH PARK AVENUE TRAILHEAD PARKING AREA FACING SOUTHEAST. - Arches National Park Main Entrance Road, Beginning at U.S. Highway 191, approximately 6 miles north of Moab, Moab, Grand County, UT
Reducing the entropy production in a collocated Lagrange-Remap scheme
NASA Astrophysics Data System (ADS)
Braeunig, Jean-Philippe
2016-06-01
The Eulerian scheme described in this article aims to perform efficient and accurate compressible multimaterial fluid flows simulations. We use a second order Collocated Lagrange-Remap scheme based on the EUCCLHYD Lagrangian scheme (Maire et al., 2007, [26]) which is conservative and uses acoustic Riemann solvers. The entropy production is studied and a correction is proposed to improve accuracy in isentropic flows by adding correction fluxes. The scheme is thus kept conservative in mass, momentum and total energy. A VOF PLIC interface reconstruction is added to the scheme. Results are presented that assess the dissipation reduction.
The role of Lagrange multiplier in Gauss-Bonnet dark energy
NASA Astrophysics Data System (ADS)
Makarenko, Andrey N.
2016-04-01
We review accelerating cosmology in Gauss-Bonnet gravity with Lagrange multiplier constraint studied in [S. Capozziello, A. N. Makarenko and S. D. Odintsov, Phys. Rev. D 87 (2013) 084037, arXiv: 1302.0093 [gr-qc], S. Capozziello, M. Francaviglia and A. N. Makarenko, Astrophys. Space Sci. 349 (2014) 603-609, arXiv: 1304.5440 [gr-qc]. Several examples of dark energy universes are presented. We can get new dark energy solutions (with additional scalar) as well as certain limits to earlier found accelerating solutions.
Domain decomposition methods for nonconforming finite element spaces of Lagrange-type
NASA Technical Reports Server (NTRS)
Cowsar, Lawrence C.
1993-01-01
In this article, we consider the application of three popular domain decomposition methods to Lagrange-type nonconforming finite element discretizations of scalar, self-adjoint, second order elliptic equations. The additive Schwarz method of Dryja and Widlund, the vertex space method of Smith, and the balancing method of Mandel applied to nonconforming elements are shown to converge at a rate no worse than their applications to the standard conforming piecewise linear Galerkin discretization. Essentially, the theory for the nonconforming elements is inherited from the existing theory for the conforming elements with only modest modification by constructing an isomorphism between the nonconforming finite element space and a space of continuous piecewise linear functions.
Field theory and weak Euler-Lagrange equation for classical particle-field systems
Qin, Hong; Burby, Joshua W; Davidson, Ronald C
2014-10-01
It is commonly believed that energy-momentum conservation is the result of space-time symmetry. However, for classical particle-field systems, e.g., Klimontovich-Maxwell and Klimontovich- Poisson systems, such a connection hasn't been formally established. The difficulty is due to the fact that particles and the electromagnetic fields reside on different manifolds. To establish the connection, the standard Euler-Lagrange equation needs to be generalized to a weak form. Using this technique, energy-momentum conservation laws that are difficult to find otherwise can be systematically derived.
The Lagrange Points in a Binary Black Hole System: Applications to Electromagnetic Signatures
NASA Technical Reports Server (NTRS)
Schnittman, Jeremy
2010-01-01
We study the stability and evolution of the Lagrange points L_4 and L-5 in a black hole (BH) binary system, including gravitational radiation. We find that gas and stars can be shepherded in with the BH system until the final moments before merger, providing the fuel for a bright electromagnetic counterpart to a gravitational wave signal. Other astrophysical signatures include the ejection of hyper-velocity stars, gravitational collapse of globular clusters, and the periodic shift of narrow emission lines in AGN.
75 FR 5104 - Notice of Inventory Completion: Madison County Historical Society, Edwardsville, IL
Federal Register 2010, 2011, 2012, 2013, 2014
2010-02-01
... National Park Service Notice of Inventory Completion: Madison County Historical Society, Edwardsville, IL... inventory of human remains in the possession of the Madison County Historical Society, Edwardsville, IL. The... made by Madison County Historical Society professional staff in consultation with representatives...
75 FR 45659 - Notice of Inventory Completion: Field Museum of Natural History, Chicago, IL
Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-03
... National Park Service Notice of Inventory Completion: Field Museum of Natural History, Chicago, IL AGENCY... History, Chicago, IL. The human remains and associated funerary objects were removed from various... made by the Field Museum of Natural History professional staff in consultation with representatives...
75 FR 52022 - Notice of Inventory Completion: Field Museum of Natural History, Chicago, IL
Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-24
... National Park Service Notice of Inventory Completion: Field Museum of Natural History, Chicago, IL AGENCY... History, Chicago, IL. The human remains and associated funerary objects were removed from near or in... History professional staff in consultation with representatives of the Confederated Tribes of the...
75 FR 438 - Notice of Inventory Completion: Field Museum of Natural History, Chicago, IL
Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-05
... National Park Service Notice of Inventory Completion: Field Museum of Natural History, Chicago, IL AGENCY... of human remains in the possession of the Field Museum of Natural History, Chicago, IL. The human.... A detailed assessment of the human remains was made by Field Museum of Natural History...
75 FR 435 - Notice of Inventory Completion: Field Museum of Natural History, Chicago, IL
Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-05
... National Park Service Notice of Inventory Completion: Field Museum of Natural History, Chicago, IL AGENCY... of human remains in the possession of the Field Museum of Natural History, Chicago, IL. The human... remains was made by Field Museum of Natural History professional staff in consultation...
Future Trends in Park Protection.
ERIC Educational Resources Information Center
Dwyer, William O.; Murrell, Dan S.
1986-01-01
The roles of ranger and park police in America's parks have shifted from visitor protection and resources management to visitor management and resources protection. Eight issues facing park police are discussed. (MT)
ERIC Educational Resources Information Center
Belanger, Charles H.
1988-01-01
Only 45 percent of Canadian research is funded and executed by the private sector. Influenced by success stories such as the U.S. Stanford Research Park, Canadians have looked at science parks as a means to diversify their economy and to increase cooperation among government, industry, and universities. (Author/MLW)
ERIC Educational Resources Information Center
Smith, Anthony Wayne
1979-01-01
Civilization is more and more intruding on the esthetic and recreational resources of the National Park System. Increased attention must be paid to controlling noise, pollution, and even the effects of urban lighting which detract from the enjoyment of the parks. (RE)
Not Available
1984-01-01
The bringing on-line of the 1.25 MW wind park at Whiskey Run, Oregon, is reported. The park features twenty-five 50 KW wind turbine generators and is expected to produce about three million kilowatt-hours per year for the Pacific Power and Light system.
Preserving DOE's Research Parks.
ERIC Educational Resources Information Center
Dale, Virginia H.; Parr, Patricia D.
1998-01-01
Seven sites are designated as Department of Energy (DOE) National Environmental Research Parks and serve as irreplaceable outdoor laboratories for scientific research and education. The DOE has recommended the disposal of nearly one- quarter of the research park land holdings. Offers suggestions for developing a plan for protecting the…
Choi, Sunghwan; Hong, Kwangwoo; Kim, Jaewook; Kim, Woo Youn
2015-03-07
We developed a self-consistent field program based on Kohn-Sham density functional theory using Lagrange-sinc functions as a basis set and examined its numerical accuracy for atoms and molecules through comparison with the results of Gaussian basis sets. The result of the Kohn-Sham inversion formula from the Lagrange-sinc basis set manifests that the pseudopotential method is essential for cost-effective calculations. The Lagrange-sinc basis set shows faster convergence of the kinetic and correlation energies of benzene as its size increases than the finite difference method does, though both share the same uniform grid. Using a scaling factor smaller than or equal to 0.226 bohr and pseudopotentials with nonlinear core correction, its accuracy for the atomization energies of the G2-1 set is comparable to all-electron complete basis set limits (mean absolute deviation ≤1 kcal/mol). The same basis set also shows small mean absolute deviations in the ionization energies, electron affinities, and static polarizabilities of atoms in the G2-1 set. In particular, the Lagrange-sinc basis set shows high accuracy with rapid convergence in describing density or orbital changes by an external electric field. Moreover, the Lagrange-sinc basis set can readily improve its accuracy toward a complete basis set limit by simply decreasing the scaling factor regardless of systems.
Modified Gauss-Bonnet gravity with the Lagrange multiplier constraint as mimetic theory
NASA Astrophysics Data System (ADS)
Astashenok, Artyom V.; Odintsov, Sergei D.; Oikonomou, V. K.
2015-09-01
In this paper we propose and extensively study mimetic f({G}) modified gravity models, with various scenarios of cosmological evolution, with or without extra matter fluids. The easiest formulation is based on the use of the Lagrange multiplier constraint. In certain versions of this theory, it is possible to realize accelerated expansion of the Universe or even unified evolution, which includes inflation with dark energy, and at the same time in the same theoretical framework, dark matter is described by the theory. This is achieved by the re-parametrization of the metric tensor, which introduces a new degree of freedom in the cosmological equations and leads to the appearance of the mimetic ‘dark matter’ component. In the context of the mimetic f({G}) theory, we also provide some quite general reconstruction schemes, which enable us to find which f({G}) gravity generates a specific cosmological evolution. In addition, we also provide the general reconstruction technique for the Lagrange multiplier f({G}) gravity. All our results are accompanied by illustrative examples, with special emphasis on bouncing cosmologies.
Augmented Lagrange Hopfield network for solving economic dispatch problem in competitive environment
NASA Astrophysics Data System (ADS)
Vo, Dieu Ngoc; Ongsakul, Weerakorn; Nguyen, Khai Phuc
2012-11-01
This paper proposes an augmented Lagrange Hopfield network (ALHN) for solving economic dispatch (ED) problem in the competitive environment. The proposed ALHN is a continuous Hopfield network with its energy function based on augmented Lagrange function for efficiently dealing with constrained optimization problems. The ALHN method can overcome the drawbacks of the conventional Hopfield network such as local optimum, long computational time, and linear constraints. The proposed method is used for solving the ED problem with two revenue models of revenue based on payment for power delivered and payment for reserve allocated. The proposed ALHN has been tested on two systems of 3 units and 10 units for the two considered revenue models. The obtained results from the proposed methods are compared to those from differential evolution (DE) and particle swarm optimization (PSO) methods. The result comparison has indicated that the proposed method is very efficient for solving the problem. Therefore, the proposed ALHN could be a favorable tool for ED problem in the competitive environment.
NASA Astrophysics Data System (ADS)
D'Antona, F.
1995-03-01
Contents: 1. Introduzione. 2. La nucleosintesi del Big Bang. 3. Il litio nelle stelle di popolazione II. 4. I modelli stellari standard. 5. Il litio negli ammassi aperti. 6. Meccanismi di distruzione "non standard". 7. I modelli non-standard applicati alla popolazione II. 8. L'evoluzione Galattica del litio. 9. Quali stelle producono litio? 10. Il litio come elemento chiave per dare un nome agli oggetti stellari più minuscoli. 11. Conclusioni.
Yang, Taiseung; Spilker, Robert L
2007-06-01
A three-dimensional (3D) contact finite element formulation has been developed for biological soft tissue-to-tissue contact analysis. The linear biphasic theory of Mow, Holmes, and Lai (1984, J. Biomech., 17(5), pp. 377-394) based on continuum mixture theory, is adopted to describe the hydrated soft tissue as a continuum of solid and fluid phases. Four contact continuity conditions derived for biphasic mixtures by Hou et al. (1989, ASME J. Biomech. Eng., 111(1), pp. 78-87) are introduced on the assumed contact surface, and a weighted residual method has been used to derive a mixed velocity-pressure finite element contact formulation. The Lagrange multiplier method is used to enforce two of the four contact continuity conditions, while the other two conditions are introduced directly into the weighted residual statement. Alternate formulations are possible, which differ in the choice of continuity conditions that are enforced with Lagrange multipliers. Primary attention is focused on a formulation that enforces the normal solid traction and relative fluid flow continuity conditions on the contact surface using Lagrange multipliers. An alternate approach, in which the multipliers enforce normal solid traction and pressure continuity conditions, is also discussed. The contact nonlinearity is treated with an iterative algorithm, where the assumed area is either extended or reduced based on the validity of the solution relative to contact conditions. The resulting first-order system of equations is solved in time using the generalized finite difference scheme. The formulation is validated by a series of increasingly complex canonical problems, including the confined and unconfined compression, the Hertz contact problem, and two biphasic indentation tests. As a clinical demonstration of the capability of the contact analysis, the gleno-humeral joint contact of human shoulders is analyzed using an idealized 3D geometry. In the joint, both glenoid and humeral head
NASA Astrophysics Data System (ADS)
Ross, Mike R.
This thesis presents a new coupling method for treating the interaction of an acoustic fluid with a flexible structure, with emphasis on handling spatially non-matching meshes. It is based on the Localized Lagrange Multiplier (LLM) method. A frame is introduced as a "mediator" or "information relay" device between the fluid and the structure at the interaction surface. The frame is discretized in terms of kinematic variables. A Lagrange multiplier field is introduced between the frame and the structure, and another one between the frame and the fluid. The function of the multiplier pair is weak enforcement of kinematic continuity. This configuration completely decouples the structure and fluid models, because each model communicates to the frame through node collocated multipliers and not directly to each other. In order to assure proper communication, energy formulations of the fluid and structure models are in terms of displacements and associated time derivatives. A novel transformation of the fluid displacement model into a fluid displacement potential model enforces the irrotational condition of the acoustic fluid. This transformation reduces the number of degrees of freedom in two and three-dimensions and is suitable for both vibration and transient analyses. The LLM method facilitates the construction of separate discretizations using different mesh generation programs, as well as use of customized time integration methods. To advance the solution in time, the LLM coupling method is combined with a partitioned solution procedure. The time-stepping computations are organized in a way that eliminates the traditional prediction step characteristic of staggered solution procedures. This is accomplished by solving for the interface variables: Lagrange multipliers and frame states, and then feeding this solution back to the coupled components. This sequence forestalls the well-known stability degradation caused by prediction, yet it retains the desirable
ERIC Educational Resources Information Center
Van Meter, Jerry R.
This booklet is a general guide to park site planning. The four basic steps involved in developing a park site are a) determination of the uses of the site, b) analysis of the site potential for these uses, c) identification of the functional relationship among the uses, and d) coordination of the uses to the park sites. Uses of park sites are…
ERIC Educational Resources Information Center
Neff, Thomas G.
2002-01-01
Describes the reorganization of the site of Ben Davis High School in Wayne Township, Indiana as an example of improvements to school parking lot design and vehicle/pedestrian traffic flow and security. Includes design drawings. (EV)
NASA Astrophysics Data System (ADS)
De Villiers, P.
2014-02-01
The Hermanus Astronomy Centre recently erected a pair of back-to-back sundials in Swallow Park in the centre of Hermanus as part of the upgrading of this historical public park by the Ward committee. Since these two are intended to be the first of many different design sundials to be erected in Hermanus by the HAC, the designs were purposefully chosen to be "unusual" to illustrate the point that even unfamiliar designs and orientations give the same end result....
Taylor-Lagrange renormalization scheme: Application to light-front dynamics
Grange, P.; Mutet, B.
2009-11-15
The recently proposed renormalization scheme based on the definition of field operators as operator valued distributions acting on specific test functions is shown to be very convenient in explicit calculations of physical observables within the framework of light-front dynamics. We first recall the main properties of this procedure based on identities relating the test functions to their Taylor remainder of any order expressed in terms of Lagrange's formulas, hence the name given to this scheme. We thus show how it naturally applies to the calculation of state vectors of physical systems in the covariant formulation of light-front dynamics. As an example, we consider the case of the Yukawa model in the simple two-body Fock state truncation.
Zou, Weiyao; Burns, Stephen A.
2012-01-01
A Lagrange multiplier-based damped least-squares control algorithm for woofer-tweeter (W-T) dual deformable-mirror (DM) adaptive optics (AO) is tested with a breadboard system. We show that the algorithm can complementarily command the two DMs to correct wavefront aberrations within a single optimization process: the woofer DM correcting the high-stroke, low-order aberrations, and the tweeter DM correcting the low-stroke, high-order aberrations. The optimal damping factor for a DM is found to be the median of the eigenvalue spectrum of the influence matrix of that DM. Wavefront control accuracy is maximized with the optimized control parameters. For the breadboard system, the residual wavefront error can be controlled to the precision of 0.03 μm in root mean square. The W-T dual-DM AO has applications in both ophthalmology and astronomy. PMID:22441462
Error estimates of Lagrange interpolation and orthonormal expansions for Freud weights
NASA Astrophysics Data System (ADS)
Kwon, K. H.; Lee, D. W.
2001-08-01
Let Sn[f] be the nth partial sum of the orthonormal polynomials expansion with respect to a Freud weight. Then we obtain sufficient conditions for the boundedness of Sn[f] and discuss the speed of the convergence of Sn[f] in weighted Lp space. We also find sufficient conditions for the boundedness of the Lagrange interpolation polynomial Ln[f], whose nodal points are the zeros of orthonormal polynomials with respect to a Freud weight. In particular, if W(x)=e-(1/2)x2 is the Hermite weight function, then we obtain sufficient conditions for the inequalities to hold:andwhere and k=0,1,2...,r.
Si, Weijian; Qu, Xinggen; Liu, Lutao
2014-01-01
A novel direction of arrival (DOA) estimation method in compressed sensing (CS) is presented, in which DOA estimation is considered as the joint sparse recovery from multiple measurement vectors (MMV). The proposed method is obtained by minimizing the modified-based covariance matching criterion, which is acquired by adding penalties according to the regularization method. This minimization problem is shown to be a semidefinite program (SDP) and transformed into a constrained quadratic programming problem for reducing computational complexity which can be solved by the augmented Lagrange method. The proposed method can significantly improve the performance especially in the scenarios with low signal to noise ratio (SNR), small number of snapshots, and closely spaced correlated sources. In addition, the Cramér-Rao bound (CRB) of the proposed method is developed and the performance guarantee is given according to a version of the restricted isometry property (RIP). The effectiveness and satisfactory performance of the proposed method are illustrated by simulation results. PMID:24678272
A study of angular momentum loss in binaries using the free Lagrange method
NASA Technical Reports Server (NTRS)
Rajasekhar, A. M.
1994-01-01
The evolution of a binary star system depends greatly on the angular momentum losses in the system brought about by gravitational radiation and mass outflow (e.g., evaporating winds and magnetic braking) from the secondary component of the binary. Using a three-dimensional hydrodynamic fluid code based on the free Lagrange method, we study the loss of specific angular momentum from a binary system due to an evaporative wind from the companion of a millisecond pulsar. We consider binaries of different mass ratios and winds of different initial velocities and in particular attempt to model the system PSR 1957+20. We are in the process of incorporating the effect of the radiation force from the pulsar and the magnetic field of the companion on the mass outflow. The latter effect would also enable us to study magnetic braking in cataclysmic variables and low-mass X-ray binaries.
On a Lagrange-Hamilton formalism describing position and momentum uncertainties
NASA Technical Reports Server (NTRS)
Schuch, Dieter
1993-01-01
According to Heisenberg's uncertainty relation, in quantum mechanics it is not possible to determine, simultaneously, exact values for the position and the momentum of a material system. Calculating the mean value of the Hamiltonian operator with the aid of exact analytic Gaussian wave packet solutions, these uncertainties cause an energy contribution additional to the classical energy of the system. For the harmonic oscillator, e.g., this nonclassical energy represents the ground state energy. It will be shown that this additional energy contribution can be considered as a Hamiltonian function, if it is written in appropriate variables. With the help of the usual Lagrange-Hamilton formalism known from classical particle mechanics, but now considering this new Hamiltonian function, it is possible to obtain the equations of motion for position and momentum uncertainties.
NASA Astrophysics Data System (ADS)
Colalongo, Luigi; Ghittorelli, Matteo; Torricelli, Fabrizio; Kovács-Vajna, Zsolt Miklos
2015-12-01
Surface-potential-based mathematical models are among the most accurate and physically based compact models of Thin-Film Transistors (TFTs) and, in turn, of Organic Thin-Film Transistors (OTFTs), available today. However, the need for iterative computations of the surface potential limits their computational efficiency and diffusion in CAD applications. The existing closed-form approximations of the surface potential are based on regional approximations and empirical smoothing functions that could result not enough accurate to model OTFTs and, in particular, transconductances and transcapacitances. In this paper we present an accurate and computationally efficient closed-form approximation of the surface potential, based on the Lagrange Reversion Theorem, that can be exploited in advanced surface-potential-based OTFTs and TFTs device models.
Augmented lagrange hopfield network for economic dispatch with multiple fuel options
Dieu, Vo Ngoc; Ongsakul, Weerakorn; Polprasert, Jirawadee
2011-06-20
This paper proposes an augmented Lagrange Hopfield network (ALHN) for solving economic dispatch (ED) problem with multiple fuel options. The proposed ALHN method is a continuous Hopfield neural network with its energy function based on augmented Lagrangian function. The advantages of ALHN over the conventional Hopfield neural network are easier use, more general applications, faster convergence, better optimal solution, and larger scale of problem implementation. The method solves the problem by directly searching the most suitable fuel among the available fuels of each unit and finding the optimal solution for the problem based on minimization of the energy function of the continuous Hopfield neural network. The proposed method is tested on systems up to 100 units and the obtained results are compared to those from other methods in the literature. The results have shown that the proposed method is efficient for solving the ED problem with multiple fuel options and favorable for implementation in large scale problems.
Si, Weijian; Qu, Xinggen; Liu, Lutao
2014-01-01
A novel direction of arrival (DOA) estimation method in compressed sensing (CS) is presented, in which DOA estimation is considered as the joint sparse recovery from multiple measurement vectors (MMV). The proposed method is obtained by minimizing the modified-based covariance matching criterion, which is acquired by adding penalties according to the regularization method. This minimization problem is shown to be a semidefinite program (SDP) and transformed into a constrained quadratic programming problem for reducing computational complexity which can be solved by the augmented Lagrange method. The proposed method can significantly improve the performance especially in the scenarios with low signal to noise ratio (SNR), small number of snapshots, and closely spaced correlated sources. In addition, the Cramér-Rao bound (CRB) of the proposed method is developed and the performance guarantee is given according to a version of the restricted isometry property (RIP). The effectiveness and satisfactory performance of the proposed method are illustrated by simulation results. PMID:24678272
Embedded Interface with Discontinuous Lagrange Multipliers for Fluid-Structure Interaction Analysis
NASA Astrophysics Data System (ADS)
Gomes, H. C.; Pimenta, P. M.
2015-03-01
This work addresses some issues in the embedded interface method for the conjoined interface between fluid and structure domains in two-dimensional Fluid-Structure Interaction (FSI) coupled problems. Our approach uses Lagrange multipliers to enforce the kinematic condition along the interface between the non-matching overlapping meshes of the structural and fluid fields in an alternative to the usual Arbitrary Lagrangian Eulerian (ALE) approaches. The main idea of our work is to discretize the embedded interface independently of the fluid and solid mesh, using discontinuous interpolating functions. The purpose of this is to avoid numerical instabilities and to simplify the implementation. In order to illustrate the method's applicability, steady and unsteady simulations of incompressible viscous flow with a moving interface as well as FSI problems involving large structural displacements were performed.
Exact nonrelativistic polarizabilities of the hydrogen atom with the Lagrange-mesh method
NASA Astrophysics Data System (ADS)
Baye, Daniel
2012-12-01
Exact analytical expressions of the dipole polarizabilities of the nonrelativistic hydrogen atom in spherical coordinates are derived with the help of the Lagrange-mesh numerical method. This method can provide exact energies and wave functions for well-chosen conditions of calculation. Exact dipole polarizabilities are obtained after an unambiguous rounding up to at least principal quantum numbers around n=30. The scalar polarizability of any nl level is given by n4[4n2+14+7l(l+1)]/4 and its tensor polarizability is given by -n4[3n2-9+11l(l+1)]l/4(2l+3), which allows the calculation of the polarizability of any hydrogen state nlm.
Mesoscale Simulations of Particulate Flows with Parallel Distributed Lagrange Multiplier Technique
Kanarska, Y
2010-03-24
Fluid particulate flows are common phenomena in nature and industry. Modeling of such flows at micro and macro levels as well establishing relationships between these approaches are needed to understand properties of the particulate matter. We propose a computational technique based on the direct numerical simulation of the particulate flows. The numerical method is based on the distributed Lagrange multiplier technique following the ideas of Glowinski et al. (1999). Each particle is explicitly resolved on an Eulerian grid as a separate domain, using solid volume fractions. The fluid equations are solved through the entire computational domain, however, Lagrange multiplier constrains are applied inside the particle domain such that the fluid within any volume associated with a solid particle moves as an incompressible rigid body. Mutual forces for the fluid-particle interactions are internal to the system. Particles interact with the fluid via fluid dynamic equations, resulting in implicit fluid-rigid-body coupling relations that produce realistic fluid flow around the particles (i.e., no-slip boundary conditions). The particle-particle interactions are implemented using explicit force-displacement interactions for frictional inelastic particles similar to the DEM method of Cundall et al. (1979) with some modifications using a volume of an overlapping region as an input to the contact forces. The method is flexible enough to handle arbitrary particle shapes and size distributions. A parallel implementation of the method is based on the SAMRAI (Structured Adaptive Mesh Refinement Application Infrastructure) library, which allows handling of large amounts of rigid particles and enables local grid refinement. Accuracy and convergence of the presented method has been tested against known solutions for a falling sphere as well as by examining fluid flows through stationary particle beds (periodic and cubic packing). To evaluate code performance and validate particle
mTOR Mediates IL-23 Induction of Neutrophil IL-17 and IL-22 Production.
Chen, Feidi; Cao, Anthony; Yao, Suxia; Evans-Marin, Heather L; Liu, Han; Wu, Wei; Carlsen, Eric D; Dann, Sara M; Soong, Lynn; Sun, Jiaren; Zhao, Qihong; Cong, Yingzi
2016-05-15
It has been shown recently that neutrophils are able to produce IL-22 and IL-17, which differentially regulate the pathogenesis of inflammatory bowel disease. However, it is still largely unknown how the neutrophil production of IL-22 and IL-17 is regulated, and their role in the pathogenesis of inflammatory bowel disease. In this study, we found that IL-23 promoted neutrophil production of IL-17 and IL-22. IL-23 stimulated the neutrophil expression of IL-23R as well as rorc and ahr. Retinoid acid receptor-related orphan receptor γ t and aryl-hydrocarbon receptor differentially regulated IL-23 induction of neutrophil IL-17 and IL-22. In addition, IL-23 induced the activation of mTOR in neutrophils. Blockade of the mTOR pathway inhibited IL-23-induced expression of rorc and ahr, as well as IL-17 and IL-22 production. By using a microbiota Ag-specific T cell-mediated colitis model, we demonstrated that depletion of neutrophils, as well as blockade of IL-22, resulted in a significant increase in the severity of colitis, thereby indicating a protective role of neutrophils and IL-22 in chronic colitis. Collectively, our data revealed that neutrophils negatively regulate microbiota Ag-specific T cell induction of colitis, and IL-23 induces neutrophil production of IL-22 and IL-17 through induction of rorc and ahr, which is mediated by the mTOR pathway. PMID:27067005
Strategies targeting the IL-4/IL-13 axes in disease.
May, Richard D; Fung, Michael
2015-09-01
IL-4 and IL-13 are pleiotropic Th2 cytokines produced by a wide variety of different cell types and responsible for a broad range of biology and functions. Physiologically, Th2 cytokines are known to mediate host defense against parasites but they can also trigger disease if their activities are dysregulated. In this review we discuss the rationale for targeting the IL-4/IL-13 axes in asthma, atopic dermatitis, allergic rhinitis, COPD, cancer, inflammatory bowel disease, autoimmune disease and fibrotic disease as well as evaluating the associated clinical data derived from blocking IL-4, IL-13 or IL-4 and IL-13 together. PMID:26255210
Parking management tactics. Volume 3: reference guide. [Parking
DiRenzo, J.F.; Cima, B.; Barber, E.
1981-06-01
Information contained in this guide was formulated from parking management experiences of 20 cities previously investigated and documented. The guide provides information on the planning, implementation, and operation of six types of parking management tactics: on-street parking supply tactics, off-street parking supply tactics for activity centers, fringe and corridor parking facilities, pricing tactics, enforcement and adjudication tactics, and marketing tactics. The guide assesses the essential aspects of the tactics as well as presents some useful analysis procedures for evaluating parking management actions. The Reference Guide is a stand-alone document for use by transportation planners and traffic engineers. It is the third volume of a three-volume series of reports on parking management. The first volume, entitled Overview, is designed for management. The second volume, entitled Overview and Case Studies, is designed for technical staff or managers who want detailed city-by-city information on parking management tactics.
FACING NORTHWEST TOWARD NORTHERN END OF PARK Candler Park ...
FACING NORTHWEST TOWARD NORTHERN END OF PARK - Candler Park Historic District, Roughly bounded by Moreland, Dekalb, McLendon & Harold Avenues, Matthews Street & Clifton Terrace, Atlanta, Fulton County, GA
FACING NORTHEAST OF NORTHERN BOUNDARY OF PARK Candler Park ...
FACING NORTHEAST OF NORTHERN BOUNDARY OF PARK - Candler Park Historic District, Roughly bounded by Moreland, Dekalb, McLendon & Harold Avenues, Matthews Street & Clifton Terrace, Atlanta, Fulton County, GA
Cytokines (interleukin-9, IL-17, IL-22, IL-25 and IL-33) and asthma
Farahani, Rahim; Sherkat, Roya; Hakemi, Mazdak Ganjalikhani; Eskandari, Nahid; Yazdani, Reza
2014-01-01
Asthma is a reversible airway obstruction that is characterized by constriction of airway smooth muscle, hyper secretion of mucus, edema and airway hyper responsiveness (AHR), mucus secretion and thickening of the basement membrane underlying the airway epithelium. During the process of airway inflammation, complex interactions of innate and adaptive immune cells as well as structural cells and their cytokines have many important roles. It was believed that airway inflammation is orchestrated by allergen specific T helper (Th) 2 cells, which recruit and accumulate in the lungs and produce a range of different effector cytokines. However, more recent studies have revealed the potential collaboration of other helper T cells and their cytokines in this process. Th17 cell may have a role in severe asthma and chronic obstructive pulmonary disease (COPD). Interleukin (IL)-9-producing subset called Th9 cell, Th22 cells which primarily secrete IL-22, IL-13 and tumor necrosis factor-α and Th25 cells via producing IL-25 are believed to be important for initiating allergic reactions and developing airway inflammation. Cytokines are important in asthma and play a critical role in orchestrating the allergic inflammatory response, although the precise role of each cytokine remains to be determined. The aim of this review is to summarize the current knowledge about the possible roles of newly identified helper T cells derived cytokines (IL-9, 17, 22, 25 and IL-33) in asthma. The potential therapeutic applications emerging from the roles of these cytokines will be discussed as well. PMID:24949298
Park, Jung I; Park, Min S
2007-08-01
Numerous procedures to eliminate medial epicanthal folds have been described. Despite an abundance of available procedures, most surgeons are reluctant to perform medial epicanthoplasty for Asian eyelid cosmetic surgery because of frequent development of unsightly scars. The Park Z-epicanthoplasty differs from the previously described procedures by placement of the incision within, as opposed to adjacent to, the eyelid skin. The Park Z-epicanthoplasty is most beneficial in type III epicanthal folds and is also widely used for type II epicanthal folds. It is most useful for individuals seeking higher double folds and outer-parallel-type double eyelid folds. PMID:17658430
CarbonTracker-Lagrange: A model-data assimilation system for North American carbon flux estimates
NASA Astrophysics Data System (ADS)
He, Wei; Chen, Huilin; van der Velde, Ivar; Andrews, Arlyn; Sweeney, Colm; Baker, Ian; Ju, Weimin; van der Laan-Luijkx, Ingrid; Tans, Pieter; Peters, Wouter
2016-04-01
, and then compared this result with similar recent inversion results. Our results suggest that: (1) The CarbonTracker-Lagrange system involving BC optimization makes mole fraction simulations more consistent with observations over all available sites, especially better fitting the aircraft sites; (2) This system is mostly insensitive to the choice of prior lateral BC products; (3) Our new Lagrangian inverse system (without continuous in-situ data) places the North American Carbon sink for the year 2010 at -0.43 to -0.69 PgC/yr, comparable to the TM5 based estimates of CarbonTracker North America (-0.41 PgC/yr) and CarbonTracker Europe (-0.62 PgC/yr). We conclude that CarbonTracker-Lagrange is a viable, credible, and efficient new tool to understand regional carbon fluxes from an atmospheric perspective.
Commentary: IL-4 and IL-13 receptors and signaling.
McCormick, Sarah M; Heller, Nicola M
2015-09-01
Interleukin (IL)-4 and IL-13 were discovered approximately 30years ago and were immediately linked to allergy and atopic diseases. Since then, new roles for IL-4 and IL-13 and their receptors in normal gestation, fetal development and neurological function and in the pathogenesis of cancer and fibrosis have been appreciated. Studying IL-4/-13 and their receptors has revealed important clues about cytokine biology and led to the development of numerous experimental therapeutics. Here we aim to highlight new discoveries and consolidate concepts in the field of IL-4 and IL-13 structure, receptor regulation, signaling and experimental therapeutics. PMID:26187331
NASA Astrophysics Data System (ADS)
Šeba, P.
2007-10-01
We show that the spacing distribution between parked cars can be obtained as a solution of certain linear distributional fixed point equation. The results are compared with the data measured on the streets of Hradec Krälový. We also discuss a relation of these results to the random matrix theory.
ERIC Educational Resources Information Center
Thomson, Gareth
1998-01-01
Presents a simulation activity in which students assume the role of grizzly bears in Banff National Park. Concepts such as species diversity, fitness, natural selection, habitat loss, extinction, and population dynamics are discussed. Children learn how human activities can affect the bear's reproductive success. Lists materials, instructional…
ERIC Educational Resources Information Center
Edwards, Susie; Roell, Amy
1998-01-01
Using discovery stations offers solutions for increasing attendance at park interpretive programs. Compact, portable stations can be used in playgrounds, special events, trailheads, picnic areas, campgrounds, nursing homes, and scouts and day camps. Describes a case in which stations were used 85 times and reached 4,927 visitors between July 1996…
ERIC Educational Resources Information Center
Norris, Don
1974-01-01
Describes an aviation trades training program offered by the Clover Park schools in Washington which exposes students to all facets of the aviation industry from record keeping to air traffic control in addition to the specific skill of piloting the aircraft. (BR)
Sen. Boxer, Barbara [D-CA
2011-01-25
05/11/2011 Committee on Energy and Natural Resources Subcommittee on National Parks. Hearings held. With printed Hearing: S.Hrg. 112-124. (All Actions) Notes: For further action, see H.R.3641, which became Public Law 112-245 on 1/10/2013. Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:
ERIC Educational Resources Information Center
Simmons, Patricia E.; Wiley, Clyde
1993-01-01
Describes several student-tested activities built around "Jurassic Park." The activities feature students engaged in role-playing scenarios, investigative research projects, journal writing and communications skills activities, cooperative learning groups, and learning experiences that make use of reading skills and mathematical knowledge. (PR)
Atmospheric Science Data Center
2013-04-15
... and to the right of image center is the Palabora Copper Mine, and the water body near upper right is Lake Massingir in Mozambique. ... South Africa showing Kruger Park, the Palabora Copper Mine, and Lake Massingir. project: MISR category: ...
Weyl-Euler-Lagrange equations on twistor space for tangent structure
NASA Astrophysics Data System (ADS)
Kasap, Zeki
2016-06-01
Twistor spaces are certain complex three-manifolds, which are associated with special conformal Riemannian geometries on four-manifolds. Also, classical mechanic is one of the major subfields for mechanics of dynamical system. A dynamical system has a state determined by a collection of real numbers, or more generally by a set of points in an appropriate state space for classical mechanic. Euler-Lagrange equations are an efficient use of classical mechanics to solve problems using mathematical modeling. On the other hand, Weyl submitted a metric with a conformal transformation for unified theory of classical mechanic. This paper aims to introduce Euler-Lagrage partial differential equations (mathematical modeling, the equations of motion according to the time) for the movement of objects on twistor space and also to offer a general solution of differential equation system using the Maple software. Additionally, the implicit solution of the equation will be obtained as a result of a special selection of graphics to be drawn.
NASA Astrophysics Data System (ADS)
Morales, Fernando; Naqvi, Iftekhar; Squires, Kyle; Piomelli, Ugo
2009-11-01
The overarching interest of the current investigations is numerical modeling of particle entrainment and deposition near sandy beds as relevant to the problem of rotorcraft brownout. Numerical simulations are being performed using an Euler-Lagrange method. Solution of the incompressible gas-phase flow field is accomplished using a fractional-step numerical method; the particulate phase is advanced using Discrete Particle Simulation. The particular flow field of interest models a rotor wake and is comprised of coherent vortices embedded in a turbulent boundary layer. The particles, once suspended, interact with the coherent wake vortices characterizing the rotor flow, and with the finer scale turbulence generated near the ground. The primary objectives are two-flow. First, to gain insight into the particle-vortex dynamics that influence transport near the bed and, second, to advance understanding of the mesoscopic particle velocity field. The latter objective requires very large particle ensembles in order to recover an Eulerian description of the particle field, important to advancing other simulation strategies for two-phase flows. Predictions of the flows for a range of particle and flow parameters will be presented.
Uncertainties of predictions from parton distribution functions. I. The Lagrange multiplier method
NASA Astrophysics Data System (ADS)
Stump, D.; Pumplin, J.; Brock, R.; Casey, D.; Huston, J.; Kalk, J.; Lai, H. L.; Tung, W. K.
2002-01-01
We apply the Lagrange multiplier method to study the uncertainties of physical predictions due to the uncertainties of parton distribution functions (PDF's), using the cross section σW for W production at a hadron collider as an archetypal example. An effective χ2 function based on the CTEQ global QCD analysis is used to generate a series of PDF's, each of which represents the best fit to the global data for some specified value of σW. By analyzing the likelihood of these ``alterative hypotheses,'' using available information on errors from the individual experiments, we estimate that the fractional uncertainty of σW due to current experimental input to the PDF analysis is approximately +/-4% at the Fermilab Tevatron, and +/-8-10% at the CERN Large Hadron Collider. We give sets of PDF's corresponding to these up and down variations of σW. We also present similar results on Z production at the colliders. Our method can be applied to any combination of physical variables in precision QCD phenomenology, and it can be used to generate benchmarks for testing the accuracy of approximate methods based on the error matrix.
Relativistic two-photon decay rates with the Lagrange-mesh method
NASA Astrophysics Data System (ADS)
Filippin, Livio; Godefroid, Michel; Baye, Daniel
2016-01-01
Relativistic two-photon decay rates of the 2 s1 /2 and 2 p1 /2 states towards the 1 s1 /2 ground state of hydrogenic atoms are calculated by using numerically exact energies and wave functions obtained from the Dirac equation with the Lagrange-mesh method. This approach is an approximate variational method taking the form of equations on a grid because of the use of a Gauss quadrature approximation. Highly accurate values are obtained by a simple calculation involving different meshes for the initial, final, and intermediate wave functions and for the calculation of matrix elements. The accuracy of the results with a Coulomb potential is improved by several orders of magnitude in comparison with benchmark values from the literature. The general requirement of gauge invariance is also successfully tested, down to rounding errors. The method provides high accuracies for two-photon decay rates of a particle in other potentials and is applied to a hydrogen atom embedded in a Debye plasma simulated by a Yukawa potential.
2D Resistive Magnetohydrodynamics Calculations with an Arbitrary Lagrange Eulerian Code
NASA Astrophysics Data System (ADS)
Rousculp, C. L.; Gianakon, T. A.; Lipnikov, K. N.; Nelson, E. M.
2015-11-01
Single fluid resistive MHD is useful for modeling Z-pinch configurations in cylindrical geometry. One such example is thin walled liners for shock physics or HEDP experiments driven by capacitor banks such as the LANL's PHELIX or Sandia-Z. MHD is also useful for modeling high-explosive-driven flux compression generators (FCGs) and their high-current switches. The resistive MHD in our arbitrary Lagrange Eulerian (ALE) code operates in one and two dimensions in both Cartesian and cylindrical geometry. It is implemented as a time-step split operator, which consists of, ideal MHD connected to the explicit hydro momentum and energy equations and a second order mimetic discretization solver for implicit solution of the magnetic diffusion equation. In a staggered grid scheme, a single-component of cell-centered magnetic flux is conserved in the Lagrangian frame exactly, while magnetic forces are accumulated at the nodes. Total energy is conserved to round off. Total flux is conserved under the ALE relaxation and remap. The diffusion solver consistently computes Ohmic heating. Both Neumann and Dirichlet boundary conditions are available with coupling to external circuit models. Example calculations will be shown.
Unsteady Euler and asymptotic solutions for Lagrange's problem of internal ballistics
NASA Astrophysics Data System (ADS)
Malmuth, N. D.
1988-01-01
A model of the transient gas motion between a projectile and the breech of a gun has been formulated based on the unsteady Euler equations. The flow field consists primarily of the interactions of a primary wave system generated by the projectile and reflections overtaking this system. A special numerical procedure has been developed to immobilize the free boundary constituting the projectile path line. This simplifies the development of a stable explicit algorithm. Results from the computational solution have been compared to asymptotic solutions for small and large times confirming the flow structure predicted by both analytic and numerical approaches and providing a basis for development of a uniformly valid asymptotic model as well as generalizations to treat finite rate burning of the propellant. In the numerical and asymptotic formulations, a central role is played by a dimensionless ballistic parameter which relates projectile inertia to initial overpressure forces. As an additional validation, the numerical results have been compared to the classical Lagrange approximation. The comparison shows that the temporal pressure variation at the breech is well predicted by this approximation but its assumption of constant density is somewhat erroneous.
Analytic Orbit Trajectory Prediction for J2-J6 Using Recursive Lagrange-Like Invariants
NASA Astrophysics Data System (ADS)
Turner, J.; Elgohary, T.
2013-09-01
Two new Lagrange-like invariants have been recently identified that allow exact arbitrary order time derivatives to be computed for the classical two-body problem, as well as the gravitational harmonic terms for J2 through J6. The recursively generated vector-valued time derivatives for the trajectory are used to develop a continuation series-based solution for propagating the position and velocity. The series-based approach is shown to provide a 75X performance boost over state-of-the-art RK12(10) numerical integration methods, while maintaining ~mm position error accuracy. A novel conjunction analysis algorithm is enabled by designing a data structure the retains all of the vector derivatives at each time evaluation point. With thousands of objects to be tracked a nearest-neighbor algorithm is presented that grids space into spatial cubes that are used to store space object identification numbers for investigating potential conjunction events. A cluster-based search algorithm is presented for managing 27 nearest-neighbor cubes for tracking objects in a cube, updating the membership lists, and performing conjunction analysis. The cluster algorithm eliminates global searching strategies for local cluster searching strategies, which has great potential for scaling up for handling potentially 100k objects.
Predicting the safe load on backpacker's arm using Lagrange multipliers method
NASA Astrophysics Data System (ADS)
Abdalla, Faisal Saleh; Rambely, Azmin Sham
2014-09-01
In this study, a technique has been suggested to reduce a backpack load by transmitting determined loads to the children arm. The purpose of this paper is to estimate school children arm muscles while load carriage as well as to determine the safe load can be carried at wrist while walking with backpack. A mathematical model, as three DOFs model, was investigated in the sagittal plane and Lagrange multipliers method (LMM) was utilized to minimize a quadratic objective function of muscle forces. The muscle forces were minimized with three different load conditions which are termed as 0-L=0 N, 1-L=21.95 N, and 2-L=43.9 N. The investigated muscles were estimated and compared to their maximum forces throughout the load conditions. Flexor and extensor muscles were estimated and the results showed that flexor muscles were active while extensor muscles showed inactivity. The estimated muscle forces were didn't exceed their maximum forces with 0-L and 1-L conditions whereas biceps and FCR muscles exceeded their maximum forces with 2-L condition. Consequently, 1-L condition is quiet safe to be carried by hand whereas 2-L condition is not. Thus to reduce the load in the backpack the transmitted load shouldn't exceed 1-L condition.
Implementation of the Euler-Lagrange and poisson equations to extract one connected region
NASA Astrophysics Data System (ADS)
Bowden, A.; Todorov, M. D.; Sirakov, N. M.
2014-11-01
This paper presents a numerical method that evolves an active contour toward the boundary of one connected image region. The numerical method implements a model which uses the solution of the Euler-Lagrange Differential Equation in order to minimize a "snake" functional. This functional is constructed as an integral of the so called internal and external energies. The internal energy is related to the moving contour. The external energy represents the image. The minimum of the functional falls on the boundaries of objects placed in the image. A half step numerical scheme implements the concepts. The contributions of the new model come from the use of the solution of the Poisson equation and development of a new penalty function to halt the contour on the object's boundary. In order to make the contour move across homogeneous regions and enlarge the capture range, we solve the Poisson equation with Dirichlet boundary conditions and generate a gradient vector field of the image. The numerical method is implemented with MatLab and uses a stop condition based on the gradient. The advantages of the model are that it has a large capture range, is accurate in detecting the boundaries of image objects, and is capable of surpassing noise. A disadvantage is that the user has to select the right values of three parameters. Several experiments with synthetic, weapon, and medical images have been conducted to validate the model. Our work continues with the goal of cutting the curve in the event multiple objects have been enveloped.
NASA Technical Reports Server (NTRS)
Weber, J. M.; Greif, R. K.
1985-01-01
The exact nonlinear equations of motion are derived for a helicopter with an extenal load suspended by fore and aft, rigid-link cables. Lagrange's form of D'Alembert's principle is used. Ten degrees of freedom are necessary to represent the motion of this system in an inertial reference frame: six for the helicopter relative to inertial space and four for the load relative to the helicopter.
IL-18/IL-1/IL-17A axis: A novel therapeutic target for neonatal sepsis?
Cross, Alan S
2016-10-01
Healthy and septic human neonates have elevated serum IL-18 levels compared with adults. Using a murine neonatal model of intraabdominal sepsis with systemic (intraperitoneal) IL-18 complementation, Wynn et al. report that IL-18 potentiated mortality in both neonatal sepsis and endotoxemia through the induction of IL-17A, and depended on IL-1 receptor 1 signaling (but not IL-1β). They propose that targeting this IL-18/IL-1/IL-17A axis may improve outcomes for human neonates with sepsis. However, given the important roles of Th17 responses and IL-18 in host defenses, some caution is in order during a potentially microbe-induced septic process in neonates. The important differences in neonatal and adult responses to sepsis highlighted in this paper emphasize the need for further study of the immune responses of neonates. PMID:27434223
ERIC Educational Resources Information Center
Cibbarelli, Pamela R.
2010-01-01
This article is the fourth in a series of articles published annually by "Computers in Libraries" surveying integrated library systems and services (ILSs). The purpose of the annual survey is to enable comparison of the ILSs that are available. ILS vendors are in constant pursuit of an ever-changing, consistently vague definition of what the…
NASA Astrophysics Data System (ADS)
Manheimer, Wallace
2005-10-01
If world development is to continue, per capita energy use in the developing world must increase to levels in the developed world. Restrictions on how much CO2 mankind can responsibly put into the atmosphere complicate the task further. Studies show that by 2050 the world will require an additional 10-30 terawatts (TW) of carbon free power, at least as much additional, as the 10 TW generated today with fossil fuel. Neither mined uranium nor renewable energy is capable of sustained power production at this level. This paper proposes, an "energy park", a self contained unit a square mile or two in area which supplies about 7 GW of electrical power or hydrogen, emits no CO2, has little or no proliferation problem, and cleans up its own waste. Most of the energy is supplied by conventional nuclear power plants. However the nuclear fuel is bred by a fusion reactor, which is the key to the energy park. The waste cleanup is done by a combination of fission, fusion, and patience. There is neither long time storage nor long distance travel for materials with proliferation risk or long lived radio nuclides. Thus only thorium comes into the park, and only electricity and hydrogen go out.
On the error propagation of semi-Lagrange and Fourier methods for advection problems☆
Einkemmer, Lukas; Ostermann, Alexander
2015-01-01
In this paper we study the error propagation of numerical schemes for the advection equation in the case where high precision is desired. The numerical methods considered are based on the fast Fourier transform, polynomial interpolation (semi-Lagrangian methods using a Lagrange or spline interpolation), and a discontinuous Galerkin semi-Lagrangian approach (which is conservative and has to store more than a single value per cell). We demonstrate, by carrying out numerical experiments, that the worst case error estimates given in the literature provide a good explanation for the error propagation of the interpolation-based semi-Lagrangian methods. For the discontinuous Galerkin semi-Lagrangian method, however, we find that the characteristic property of semi-Lagrangian error estimates (namely the fact that the error increases proportionally to the number of time steps) is not observed. We provide an explanation for this behavior and conduct numerical simulations that corroborate the different qualitative features of the error in the two respective types of semi-Lagrangian methods. The method based on the fast Fourier transform is exact but, due to round-off errors, susceptible to a linear increase of the error in the number of time steps. We show how to modify the Cooley–Tukey algorithm in order to obtain an error growth that is proportional to the square root of the number of time steps. Finally, we show, for a simple model, that our conclusions hold true if the advection solver is used as part of a splitting scheme. PMID:25844018
Automated Car Park Management System
NASA Astrophysics Data System (ADS)
Fabros, J. P.; Tabañag, D.; Espra, A.; Gerasta, O. J.
2015-06-01
This study aims to develop a prototype for an Automated Car Park Management System that will increase the quality of service of parking lots through the integration of a smart system that assists motorist in finding vacant parking lot. The research was based on implementing an operating system and a monitoring system for parking system without the use of manpower. This will include Parking Guidance and Information System concept which will efficiently assist motorists and ensures the safety of the vehicles and the valuables inside the vehicle. For monitoring, Optical Character Recognition was employed to monitor and put into list all the cars entering the parking area. All parking events in this system are visible via MATLAB GUI which contain time-in, time-out, time consumed information and also the lot number where the car parks. To put into reality, this system has a payment method, and it comes via a coin slot operation to control the exit gate. The Automated Car Park Management System was successfully built by utilizing microcontrollers specifically one PIC18f4550 and two PIC16F84s and one PIC16F628A.
Euler-Lagrange Modeling of Vortex Interaction with a Particle-Laden Turbulent Boundary Layer
NASA Astrophysics Data System (ADS)
Morales, Fernando
Rotorcraft operation in austere environments can result in difficult operating conditions, particularly in the vicinity of sandy areas. The uplift of sediment by rotorcraft downwash, a phenomenon known as brownout, hinders pilot visual cues and may result in a potentially dangerous situation. Brownout is a complex multiphase flow problem that is not unique and depends on both the characteristics of the rotorcraft and the sediment. The lack of fundamental understanding constrains models and limits development of technologies that could mitigate the adverse effects of brownout. This provides the over-arching motivation of the current work focusing on models of particle-laden sediment beds. The particular focus of the current investigations is numerical modeling of near-surface fluid-particle interactions in turbulent boundary layers with and without coherent vortices superimposed on the background flow, that model rotorcraft downwash. The simulations are performed with two groups of particles having different densities both of which display strong vortex-particle interaction close to the source location. The simulations include cases with inter-particle collisions and gravitational settling. Particle effects on the fluid are ignored. The numerical simulations are performed using an Euler- Lagrange method in which a fractional-step approach is used for the fluid and with the particulate phase advanced using Discrete Particle Simulation. The objectives are to gain insight into the fluid-particle dynamics that influence transport near the bed by analyzing the competing effects of the vortices, inter-particle collisions, and gravity. Following the introduction of coherent vortices into the domain, the structures convect downstream, dissipate, and then recover to an equilibrium state with the boundary layer. The particle phase displays an analogous return to an equilibrium state as the vortices dissipate and the boundary layer recovers, though this recovery is slower than
77 FR 49349 - Safety Zone; Chicago Air and Water Show, Lake Michigan, Chicago, IL
Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-16
... DHS Department of Homeland Security FR Federal Register NPRM Notice of Proposed Rulemaking A... CFR Part 165 RIN 1625-AA00 Safety Zone; Chicago Air and Water Show, Lake Michigan, Chicago, IL AGENCY... deviation to the Chicago Air and Water Show safety zone on Lake Michigan near Lincoln Park. This action...
77 FR 23504 - Notice of Inventory Completion: Illinois State Museum, Springfield, IL
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-19
... National Park Service Notice of Inventory Completion: Illinois State Museum, Springfield, IL AGENCY... inventory of human remains, in consultation with the appropriate Indian tribes, and has determined that... Act (NAGPRA), 25 U.S.C. 3003, of the completion of an inventory of human remains under the control...
78 FR 2436 - Notice of Inventory Completion: Illinois State Museum, Springfield, IL
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-11
... National Park Service Notice of Inventory Completion: Illinois State Museum, Springfield, IL AGENCY... inventory of human remains, in consultation with the appropriate Indian tribes, and has determined that... Act (NAGPRA), 25 U.S.C. 3003, of the completion of an inventory of human remains under the control...
A low diffusive Lagrange-remap scheme for the simulation of violent ai-water free-surface flows
NASA Astrophysics Data System (ADS)
Bernard-Champmartin, Aude; De Vuyst, Florian
2014-10-01
In 2002, Després and Lagoutière [17] proposed a low-diffusive advection scheme for pure transport equation problems, which is particularly accurate for step-shaped solutions, and thus suited for interface tracking procedure by a color function. This has been extended by Kokh and Lagoutière [28] in the context of compressible multifluid flows using a five-equation model. In this paper, we explore a simplified variant approach for gas-liquid three-equation models. The Eulerian numerical scheme has two ingredients: a robust remapped Lagrange solver for the solution of the volume-averaged equations, and a low diffusive compressive scheme for the advection of the gas mass fraction. Numerical experiments show the performance of the computational approach on various flow reference problems: dam break, sloshing of a tank filled with water, wate-water impact and finally a case of Rayleigh-Taylor instability. One of the advantages of the present interface capturing solver is its natural implementation on parallel processors or computers. wave formation and wave breaking; wall wave impacts, local pressure peaks and pressure loadings; formation of air pockets; ejection, fragmentation of liquid droplets; Archimedes buoyancy effect with rising of bubbles and fall of droplets; effects of gas compressibility inducing a gas-to-liquid response by a pressure wave, etc. In this paper, we consider immiscible gas-liquid two-phase flow problems. The strong ratio of mass density between gas and liquid (typically 1:1000) is known to be a source of numerical stiffness and numerical instability. Therefore robust computational approaches supporting high density ratio have to be considered. Among the family of conservative Finite Volume methods (FVM), the Lagrange-remapped solvers (see e.g. [42,45,6,4,25,2]) provide both robustness and stability with achievement of mathematical properties of positiveness and entropy compatibility.Lagrange-remap numerical schemes (also referred to as Eule-Lagrange
Amarilyo, Gil; Lourenço, Elaine V; Shi, Fu-Dong; La Cava, Antonio
2014-07-15
The proinflammatory activity of IL-17-producing Th17 cells has been associated with the pathogenesis of several autoimmune diseases. In this article, we provide direct evidence for a role of IL-17 in the pathogenesis of systemic lupus erythematosus (SLE). The induction of SLE by pristane in IL-17-sufficient wild-type mice did not occur in IL-17-deficient mice, which were protected from development of lupus autoantibodies and glomerulonephritis. The protection from SLE in IL-17-deficient mice was associated with a reduced frequency of CD3(+)CD4(-)CD8(-) double-negative T cells and an expansion of CD4(+) regulatory T cells, and did not depend on Stat-1 signaling. These data affirm the key role of IL-17 in the pathogenesis of SLE and strengthen the support for IL-17 blockade in the therapy of SLE. PMID:24920843
Salute to the National Park Service
ERIC Educational Resources Information Center
Carpenter, Edward K.
1976-01-01
Current National Parks Service's design policy is summarized and the manner in which this policy produces national park transportation, planning, visitor center siting, architecture, preservation, and exhibits, is detailed. Organizations lobbying for better parks are listed. (BT)
Yin, Zhinan; Bahtiyar, Gul; Zhang, Na; Liu, Lanzhen; Zhu, Ping; Robert, Marie E; McNiff, Jennifer; Madaio, Michael P; Craft, Joe
2002-08-15
MRL/MpJ-Tnfrsf6(lpr) (MRL/MpJ-Fas(lpr); MRL-Fas(lpr)) mice develop a spontaneous lupus syndrome closely resembling human systemic lupus erythematosus. To define the role of IL-10 in the regulation of murine lupus, IL-10 gene-deficient (IL-10(-/-)) MRL-Fas(lpr) (MRL-Fas(lpr) IL-10(-/-)) mice were generated and their disease phenotype was compared with littermates with one or two copies of an intact IL-10 locus (MRL-Fas(lpr) IL-10(+/-) and MRL-Fas(lpr) IL-10(+/+) mice, respectively). MRL-Fas(lpr) IL-10(-/-) mice developed severe lupus, with earlier appearance of skin lesions, increased lymphadenopathy, more severe glomerulonephritis, and higher mortality than their IL-10-intact littermate controls. The increased severity of lupus in MRL-Fas(lpr) IL-10(-/-) mice was closely associated with enhanced IFN-gamma production by both CD4(+) and CD8(+) cells and increased serum concentration of IgG2a anti-dsDNA autoantibodies. The protective effect of IL-10 in this lupus model was further supported by the observation that administration of rIL-10 reduced IgG2a anti-dsDNA autoantibody production in wild-type MRL-Fas(lpr) animals. In summary, our results provide evidence that IL-10 can down-modulate murine lupus through inhibition of pathogenic Th1 cytokine responses. Modulation of the level of IL-10 may be of potential therapeutic benefit for human lupus. PMID:12165544
An Amusement Park Physics Competition
ERIC Educational Resources Information Center
Moll, Rachel F.
2010-01-01
Amusement park physics is a popular way to reinforce physics concepts and to motivate physics learners. This article describes a novel physics competition where students use simple tools to take amusement park ride measurements and use the data to answer challenging exam questions. Research into the impact of participating in the competition…
Jo, Seunghyun; Kim, Eunsom; Kwak, Areum; Lee, Jungmin; Hong, Jaewoo; Lee, Jongho; Youn, Sulah; Bae, Suyoung; Kim, Busun; Ryoo, Soyoon; Kang, Tae-Bong; Her, Erk; Choi, Dong-Ki; Kim, Yong-Sung; Lee, Youngmin; Jhun, Hyunjhung; Kim, Soohyun
2016-07-01
Interleukin-33 (IL-33) receptors are composed of ST2 (also known as IL-1R4), a ligand binding chain, and IL-1 receptor accessory protein (IL-1RAcP, also known as IL-1R3), a signal transducing chain. IL-1R3 is a common receptor for IL-1α, and IL-1β, IL-33, and three IL-36 isoforms. A549 human lung epithelial cells are highly sensitive to IL-1α and IL-1β but not respond to IL-33. The lack of responsiveness to IL-33 is due to ST2 expression. ST2 was stably transfected into A549 cells to reconstitute its activity. RT-PCR and FACS analysis confirmed ST2 expression on the cell surface of A549/ST2 cells. Upon IL-33 stimulation, A549/ST2 cells induced IL-8 and IL-6 production in a dose dependent manner while A549/mock cells remained unresponsive. There was no difference in IL-1α and IL-1β activity in A549/ST2 cells compared to A549/mock cells despite the fact that IL-33 shares IL-1R3 with IL-1α/β. IL-33 activated inflammatory signaling molecules in a time- and dose-dependent manner. Anti-ST2 antibody and soluble recombinant ST2-Fc abolished IL-33-induced IL-6 and IL-8 production in A549/ST2 cells but the IL-1 receptor antagonist failed to block IL-33-induced cytokines. This result demonstrates for the first time the reconstitution of ST2 in A549 human lung epithelial cell line and verified its function in IL-33-mediated cytokine production and signal transduction. PMID:27031441
Wheeling and Dealing in the National Parks
ERIC Educational Resources Information Center
Howe, Sydney
1973-01-01
Motor vehicles and commercialism have generated serious problems within the national park system. A Conservation Foundation suggests new directions in management for the National Park Service. (Editors)
NASA Astrophysics Data System (ADS)
Yang, Zi-Jiang; Qin, Pan
2016-07-01
This paper considers the problem of distributed synchronisation tracking control of multiple Euler-Lagrange systems on a directed graph which contains a spanning tree with the leader node being the root. To design the high performance distributed controllers, a virtual double-integrator is introduced in each agent and is controlled by a virtual distributed linear high-gain synchronisation tracking controller, so that the position and velocity of each agent track those of the reference trajectory with arbitrarily short transient time and small ultimate tracking error. Then taking the double-integrator's position and velocity as the estimates of those of the reference trajectory, in each generalised coordinate of each Euler-Lagrange agent, a local controller with a disturbance observer and a sliding mode control term is designed, to suppress the mutual interactions among the agents and the modelling uncertainties. The boundedness of the overall signals and the synchronisation tracking control performance are analysed, and the conditions for guaranteed control performance are clarified. Simulation examples are provided to demonstrate the performance of the distributed controllers.
NASA Astrophysics Data System (ADS)
Hammerl, Georg; Wall, Wolfgang A.
2015-12-01
An Euler-Lagrange model is developed to simulate bubbly flow around an obstacle with the aim to resolve large and meso-scales of cavitation phenomena. The volume averaged Navier-Stokes equations are discretized using finite elements on an unstructured grid with a variational multiscale method. The trajectory of each bubble is tracked using Newton's second law. Furthermore, bubble interaction is modeled with a soft sphere contact model to obtain a four-way coupled approach. The new features presented in this work, besides using a variational multiscale method in an Euler-Lagrange framework, is an improved computation of the void fraction. A second order polynomial is used as filtering function and the volume integral is transformed by applying the divergence theorem twice, leading to line integrals which can be integrated analytically. Therefore, accuracy of void fraction computation is increased and discontinuities are avoided as is the case when the kernel touches a Gauss point across time steps. This integration technique is not limited to the chosen spatial discretization. The numerical test case considers flow in a channel with a cylindrical obstacle. Bubbles are released close to the inflow boundary and void fractions up to 30% occur at the stagnation point of the obstacle.
NASA Astrophysics Data System (ADS)
Wu, X.; Zhou, L.
This chapter investigates a new time-domain finite element method (TDFEM) based on Lagrange interpolation and high-order Whitney elements for temporal and spatial expansion, respectively. This approach is motivated by goals of achieving computational efficiency and further applying to ultra-wideband (UWB) antenna simulation. Traditional TDFEM scheme is based on Galerkin's method with a piecewise linear temporal expansion of the electric field. In this chapter, we use a second-order Lagrange interpolation polynomial instead of linear temporal expansion. Such a multistep interpolation scheme leads to a more robust interpolation and a more efficient approximation. Moreover, this method allows for a consistent time discretization of the electric field vector wave equation with the augmented perfectly matched layer (PML) regions. The novel scheme is first verified by applying on a canonical problem, i.e., the cavity resonance problem. The results achieved by this scheme were in close agreement with the analytical solution. We finally applied this scheme to a dipole antenna and compared the results from the TDFEM by using piecewise linear temporal basis function. We found that they were in good agreement with each other.
IL-15 temporally reorients IL-10 biased B-1a cells toward IL-12 expression.
Kanti Ghosh, Amlan; Sinha, Debolina; Mukherjee, Subhadeep; Biswas, Ratna; Biswas, Tapas
2016-03-01
Interleukin (IL)-15 is known to strongly modulate T-cell function; however, its role in controlling mucosal immunity, including its ability to modulate B-1a cell activity, remains to be elucidated. Here, we show that IL-15 upregulates activation molecules and the costimulatory molecule CD80 on viable B-1a cells. Cell activation was accompanied by the depletion of sialic acid-binding immunoglobulin-like lectin (Siglec)-G, an inhibitor of cell activation that is present on B-1a cells. The IL-15 receptor CD122 was stimulated on B-1a cells by the cytokine showing its direct involvement in IL-15-mediated responses. IL-10 is responsible for the long term survival of B-1a cells in culture, which is initially promoted by IL-15. The upregulation of IL-10 was followed by the appearance of suppressor of cytokine signaling (SOCS)1 in the presence of IL-15 and the loss of IL-10. This resulted in the cells switching to IL-12 expression. This anti-inflammatory to pro-inflammatory shift in the B-1a cell character was independent of the cell-specific marker CD5, which remained highly expressed throughout the in vitro life of the cells. The presence of the immunosuppressive receptor programmed cell death (PD)-1 and its ligand PD-L2 were features of a predominantly IL-10 response. PD-1 and PD-L2 can mediate juxtacrine signaling. However, the abrogation of PD-1 and its ligand was observed when the cells expressed IL-12. This demonstrates an inverse relationship between the receptor and ligand and the pro-inflammatory cytokine. The induction of IgM and IgA, which can play pivotal roles in mucosal immunity, was promoted in the presence of IL-15. Collectively, the data implicate IL-15 as the master cytokine that induces B-1a cells to mount a mucosal immune response. PMID:25748019
Perception of urban park soundscape.
Tse, Man Sze; Chau, Chi Kwan; Choy, Yat Sze; Tsui, Wai Keung; Chan, Chak Ngai; Tang, Shiu Keung
2012-04-01
A number of studies have been initiated to explore how to improve the soundscape quality in urban parks. However, good soundscape quality in parks cannot be provided without a thorough understanding of the complex relationships among sound, environment, and individuals. As acoustic comfort is considered to be an important outcome of soundscape quality, this study investigates the relative impacts of the factors influencing acoustic comfort evaluation by formulating a multivariate ordered logit model. This study also explores the inter-relationships among acoustic comfort evaluation, acceptability of the environment, and preference to stay in a park using a path model. A total of 595 valid responses were obtained from interview surveys administered in four parks in Hong Kong while objective sound measurements were carried out at the survey spots concurrently. The findings unveil that acoustic comfort evaluation, besides visual comfort evaluation of landscape, also plays an important role on users' acceptability of the urban park environment. Compared with all the studied acoustic related factors, acoustic comfort evaluation serves as a better proxy for park users' preference to stay in urban parks. Hearing the breeze will significantly increase the likelihood of individuals in giving high acoustic comfort evaluation. Conversely, hearing the sounds from heavy vehicles or sounds from bikes will significantly reduce the likelihood in giving a high acoustic evaluation. PMID:22501055
Aftermath of Griffith Park Fire
NASA Technical Reports Server (NTRS)
2007-01-01
In mid-May 2007, wind-driven flames raced through Griffith Park in Los Angeles, forcing hasty evacuations and threatening numerous famous landmarks and tourist spots, such as the Los Angeles Zoo and the Hollywood Sign. Ultimately, no one was injured in the fire, which may have been started by a cigarette. About 800 acres burned in the urban park, which is itself a Hollywood landmark, having been the location for several movies, including Rebel Without A Cause. This image of the park was captured by the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) on NASA's Terra satellite on June 6, 2007, about a month after the fire. ASTER detects both visible and infrared wavelengths of light, and both kinds have been used to make this image. Vegetation appears in various shades of red, while the burned areas appear charcoal. Roads and dense urban areas appear purplish-gray or white. Water is dark blue. Large burned areas are evident in the northwest and southeast parts of the park, with scattered smaller patches along the southern margin. Some botanical gardens and parts of a bird sanctuary, as well as some park structures like restrooms, were destroyed. The park's unburned, natural vegetation appears brick red, while the irrigated golf courses adjacent to the park are bright red. NASA image created by Jesse Allen, using data provided courtesy of the NASA/GSFC/MITI/ERSDAC/JAROS, and U.S./Japan ASTER Science Team.
NASA Astrophysics Data System (ADS)
Irschik, H.; Krommer, M.; Nader, M.; Vetyukov, Y.; von Garssen, H.-G.
2015-01-01
The present paper is concerned with Lagrange's Equations, applied to a deformable body in the presence of rigid body degrees of freedom. The Lagrange description of Continuum Mechanics is used. An exact version of the Equations is derived first. This version, which represents an identical extension of the Fundamental Law of Dynamics, does involve the idea of virtual motions. The virtual motion is described in the framework of the Ritz-Ansatz, but our derivation does not make use of D'Alemberts principle, the principle of virtual work, or variational principles. From the exact version, by involving arguments related to the Galerkin approximation technique, we derive an approximate Ritz type version of Lagrange's Equations. This approximate version coincides with the traditional one, which is based on the notion of kinetic energy. However, since our derivation stems from the Fundamental Law of Dynamics, we have at our disposal an alternative formulation, which is based on the notion of local momentum. This momentum based version, which is the main topic of the present contribution, can be used for the purpose of performing independent checks of the energy based version of Lagrange's Equations. The momentum based version also clarifies that and how certain terms in the energy based version do cancel out. The momentum based version is worked out in the framework of the Floating Frame of Reference Formulation of Multibody Dynamics. Explicit formulas for the single terms of Lagrange's Equations are derived for the translational, rotational and flexible degrees of freedom of the deformable body, respectively. Corresponding Lagrange's Equations are explained in the light of the relations of Balance of Total Momentum, Balance of Total Moment of Momentum, of the Mean Stress Theorem and the notion of Virial of Forces. An embedding into the literature is given.
Leonard, Warren J.; Wan, Chi-Keung
2016-01-01
IL-21 is a type I cytokine produced by T cells and natural killer T cells that has pleiotropic actions on a wide range of immune and non-immune cell types. Since its discovery in 2000, extensive studies on the biological actions of IL-21 have been performed in vitro and in vivo. Recent reports describing patients with primary immunodeficiency caused by mutations of IL21 or IL21R have further deepened our knowledge of the role of this cytokine in host defense. Elucidation of the molecular mechanisms that mediate IL-21’s actions has provided the rationale for targeting IL-21 and IL-21 downstream mediators for therapeutic purposes. The use of next-generation sequencing technology has provided further insights into the complexity of IL-21 signaling and has identified transcription factors and co-factors involved in mediating the actions of this cytokine. In this review, we discuss recent advances in the biology and signaling of IL-21 and how this knowledge can be potentially translated into clinical settings. PMID:26966515
78 FR 14822 - Proposed Information Collection; National Park Service Concessions
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-07
... National Park Service Proposed Information Collection; National Park Service Concessions AGENCY: National Park Service, Interior. ACTION: Notice; request for comments. SUMMARY: We (National Park Service, NPS... Madonna L. Baucum, Information Collection Clearance Officer, National Park Service, 1201 I Street NW.,...
Anderson, Barbara G; Quinn, LeBris S
2016-03-01
IL-15 is a cytokine that is part of the innate immune system, as well as a proposed myokine released from skeletal muscle during physical exercise that mediates many of the positive physiological effects of exercise. Many of the immune functions of IL-15 are mediated by juxtacrine signaling via externalized IL-15 bound to membrane-associated IL-15 receptor-α (IL-15Rα). Serum and plasma samples also contain measurable concentrations of IL-15, believed to arise from proteolytic cleavage of membrane-associated IL-15/IL-15Rα complexes to generate soluble IL-15/IL-15Rα species. Here, we validate commercial assays that can distinguish the free form of IL-15 and IL-15/IL-15Rα complexes. These assays showed that most (86%) IL-15 in mouse serum resides in the free state, with a minor proportion (14%) residing in complex with IL-15Rα. Given the much shorter half-life of free IL-15 compared with IL-15/IL-15Rα complexes, these findings cast doubt on the currently accepted model for IL-15 secretion from cleavage of membrane-bound IL-15/IL-15Rα and suggest that IL-15 is released as a free molecule by an unknown mechanism. PMID:26812159
IL-1beta, IL-6 and IL-8 levels in gyneco-obstetric infections.
Basso, Beatriz; Giménez, Francisco; López, Carlos
2005-01-01
OBJECTIVE: During pregnancy cytokines and inflammatory mediators stimulate the expression of prostaglandin, the levels of which determine the onset of labor. The aim of this work was to study interleukin IL-1beta, IL-6 and IL-8 levels in the vaginal discharge, serum and urine of pregnant women with genitourinary infection before and after specific treatment. One hundred and fifty-one patients were studied during the second or third trimester of their pregnancy. METHODS: The selected patients were: healthy or control group (n = 52), those with bacterial vaginosis (n = 47), those with vaginitis (n = 37), those with asymptomatic urinary infection (n = 15) and post-treatment. The level of cytokines was assayed by ELISA test. The Mann-Whitney U-test was used for statistical analysis. RESULTS: The IL-1beta levels in vaginal discharge were: control 103.5 +/- 24.2 pg/ml, bacterial vaginosis 1030 +/- 59.5, vaginitis 749.14 +/- 66.7l ( p < 0.0001), post-treatment 101.4 +/- 28.7. IL-6 values were similar in both control and infected groups, and there were no patients with chorioamnionitis. In vaginal discharge IL-6: control 14.2 +/- 3.9 pg/ml, bacterial vaginosis 13.2 +/- 3.8, vaginitis 13 +/- 4.2. IL-8 levels were: control 1643 +/- 130.3 pg/ml, bacterial vaginosis 2612.7 +/- 257.7, vaginitis 3437 +/- 460 (p < 0.0001), post-treatment 1693 +/- 126.6. In urine the results were: control 40.2 +/- 17 pg/ml, asymptomatic urinary infection 1200.7 +/- 375 (p < 0.0001). In patients with therapeutic success both IL-1beta and IL-8 returned to normal levels. CONCLUSIONS: Genitourinary infections induce a significant increase in IL-1beta and IL-8 levels in vaginal secretions, and IL-8 in urine as well. Both cytokines could be useful as evolutive markers of infection. PMID:16338780
Teacher's Guide to Independence National Historical Park.
ERIC Educational Resources Information Center
National Park Service (Dept. of Interior), Philadelphia, PA. Independence National Historical Park.
Independence National Historical Park, located in Philadelphia, Pennsylvania, is operated by the National Park Service. The park was authorized by an Act of Congress on June 28, 1948, and formally established on July 4, 1956. The mission of Independence National Historical Park is to preserve its stories, buildings, and artifacts as a source of…
ERIC Educational Resources Information Center
Shattuck, J. Bruce
1988-01-01
Responses of 380 park maintenance and facility managers to a questionnaire provided information on how they try to prevent vandalism affecting signs, picnic and related services, and sanitary facilities. (CB)
Jurassic Park: Adventure in Learning.
ERIC Educational Resources Information Center
Shams, Marcia; Boteler, Trina
1993-01-01
Describes using the movie "Jurassic Park" as a foundation for a middle school interdisciplinary unit involving science, math, language arts, history, and geography. Suggested books and activities are presented. (PR)
Multinational underground nuclear parks
Myers, C.W.; Giraud, K.M.
2013-07-01
Newcomer countries expected to develop new nuclear power programs by 2030 are being encouraged by the International Atomic Energy Agency to explore the use of shared facilities for spent fuel storage and geologic disposal. Multinational underground nuclear parks (M-UNPs) are an option for sharing such facilities. Newcomer countries with suitable bedrock conditions could volunteer to host M-UNPs. M-UNPs would include back-end fuel cycle facilities, in open or closed fuel cycle configurations, with sufficient capacity to enable M-UNP host countries to provide for-fee waste management services to partner countries, and to manage waste from the M-UNP power reactors. M-UNP potential advantages include: the option for decades of spent fuel storage; fuel-cycle policy flexibility; increased proliferation resistance; high margin of physical security against attack; and high margin of containment capability in the event of beyond-design-basis accidents, thereby reducing the risk of Fukushima-like radiological contamination of surface lands. A hypothetical M-UNP in crystalline rock with facilities for small modular reactors, spent fuel storage, reprocessing, and geologic disposal is described using a room-and-pillar reference-design cavern. Underground construction cost is judged tractable through use of modern excavation technology and careful site selection. (authors)
IL-1β Suppresses Innate IL-25 and IL-33 Production and Maintains Helminth Chronicity
Zaiss, Mario M.; Maslowski, Kendle M.; Mosconi, Ilaria; Guenat, Nadine; Marsland, Benjamin J.; Harris, Nicola L.
2013-01-01
Approximately 2 billion people currently suffer from intestinal helminth infections, which are typically chronic in nature and result in growth retardation, vitamin A deficiency, anemia and poor cognitive function. Such chronicity results from co-evolution between helminths and their mammalian hosts; however, the molecular mechanisms by which these organisms avert immune rejection are not clear. We have found that the natural murine helminth, Heligmosomoides polygyrus bakeri (Hp) elicits the secretion of IL-1β in vivo and in vitro and that this cytokine is critical for shaping a mucosal environment suited to helminth chronicity. Indeed in mice deficient for IL-1β (IL-1β−/−), or treated with the soluble IL-1βR antagonist, Anakinra, helminth infection results in enhanced type 2 immunity and accelerated parasite expulsion. IL-1β acts to decrease production of IL-25 and IL-33 at early time points following infection and parasite rejection was determined to require IL-25. Taken together, these data indicate that Hp promotes the release of host-derived IL-1β that suppresses the release of innate cytokines, resulting in suboptimal type 2 immunity and allowing pathogen chronicity. PMID:23935505
Valizadeh, Azar; Khosravi, Afra; Zadeh, Layla Jafar; Parizad, Elaheh Gholami
2015-04-01
IL-25 a 2o KDa protein mostly known as IL-17E, encoded by chromosome 14, and containing 117 amino acids. Cytokine IL-17 family consists of 6 members; IL-17A to IL-17F, among which IL-25 has a unique structure and function. The receptor of IL-25 (IL-17BR) is highly expressed in the main Th2 cells. IL-25 regulates the internal safety of adaptive immune responses which leads to begin allergic diseases and plays a role in stimulation of pulmonary mucosal cells and fibroblasts. IL-25 can also have some effects on production of other cytokines. For instance, production of IL-25 in human and mice or injection of IL-25 to animals has resulted in production of high concentrations of Th2 cytokines, including IL-4, IL-5, and IL-13. Pilot studies have shown that mRNA of IL-25 has a high expression in Th2 cells. However, the mechanism through which IL-25 leads to Th2 immune response is still unknown. Reaction between IL-25 and IL-17BR leads to activation of transcription factors, such as NF-KB, STAT6, GATA3, NF-ATC1, JUNNB, MAPK, and JNK. IL-25 has been used against the kidney damage in mice. A large number of researchers in various countries, including the U.S. and Taiwan, have stated that IL-25 is a strong inflammatory cytokine protein which is involved in allergic inflammations. PMID:26023586
NASA Technical Reports Server (NTRS)
Klein, L. R.
1974-01-01
The free vibrations of elastic structures of arbitrary complexity were analyzed in terms of their component modes. The method was based upon the use of the normal unconstrained modes of the components in a Rayleigh-Ritz analysis. The continuity conditions were enforced by means of Lagrange Multipliers. Examples of the structures considered are: (1) beams with nonuniform properties; (2) airplane structures with high or low aspect ratio lifting surface components; (3) the oblique wing airplane; and (4) plate structures. The method was also applied to the analysis of modal damping of linear elastic structures. Convergence of the method versus the number of modes per component and/or the number of components is discussed and compared to more conventional approaches, ad-hoc methods, and experimental results.
NASA Technical Reports Server (NTRS)
Hopkins, Randall C.; Stahl, H. Philip
2007-01-01
The payload mass and volume capabilities of the planned Ares V launch vehicle provide the science community with unprecedented opportunities to place large science payloads into low earth orbit and beyond. One example, the outcome of a recent study conducted at the NASA Marshall Space Flight Center, is a large, monolithic telescope with a primary mirror diameter of 6.2 meters placed into a halo orbit about the second Sun-Earth Lagrange point, or L2, approximately 1.5 million kin beyond Earth's orbit. Operating in the visible and ultraviolet regions of the electromagnetic spectrum, such a large telescope would allow astronomers to detect bio-signatures and characterize the atmospheres of transiting exoplanets, provide high resolution imaging three or more times better than the Hubble Space Telescope and the James Webb Space Telescope, and observe the ultraviolet light from warm baryonic matter.
Anticancer Cytokines: Biology and Clinical Effects of IFN-α2, IL-2, IL-15, IL-21, and IL-12
Floros, Theofanis; Tarhini, Ahmad A.
2015-01-01
Efforts over nearly four decades have focused on ways to use cytokines to manipulate the host immune response towards cancer cell recognition and eradication. Significant advances were achieved with interleukin-2 (IL-2) and interferon-α (IFN-α), primarily in the treatment of patients with melanoma and renal cell carcinoma. However, the utility of other cytokines showing promise in the preclinical setting has not been established largely because of toxicity, the complex functionality of each cytokine and the difficulty mimicking in preclinical models the human environment. In this paper we will review the basic biology and the clinical experiences with IFN-α, IL-2, IL-15, IL-21 and IL-12. We will also review ongoing clinical trials and discuss future directions including potential use of cytokines in combination with other effective immunotherapy approaches which have come of age in recent years. PMID:26320059
NASA Astrophysics Data System (ADS)
Odintsov, S. D.; Oikonomou, V. K.
2016-01-01
We study mimetic F (R ) gravity with a potential and Lagrange multiplier constraint. In the context of these theories, we introduce a reconstruction technique which enables us to realize arbitrary cosmologies, given the Hubble rate and an arbitrarily chosen F (R ) gravity. We exemplify our method by realizing cosmologies that are in concordance with current observations (Planck data) and also well-known bouncing cosmologies. The attribute of our method is that the F (R ) gravity can be arbitrarily chosen, so we can have the appealing features of the mimetic approach combined with the known features of some F (R ) gravities, which unify early-time with late-time acceleration. Moreover, we study the existence and the stability of de Sitter points in the context of mimetic F (R ) gravity. In the case of unstable de Sitter points, it is demonstrated that graceful exit from inflation occurs. We also study the Einstein-frame counterpart theory of the Jordan-frame mimetic F (R ) gravity, and we discuss the general properties of the theory and exemplify our analysis by studying a quite interesting (from a phenomenological point of view) model with two scalar fields. We also calculate the observational indices of the two-scalar-field model, by using the two-scalar-field formalism. Furthermore, we extensively study the dynamical system that corresponds to the mimetic F (R ) gravity, by finding the fixed points and studying their stability. Finally, we modify our reconstruction method to function in the inverse way and thus yield which F (R ) gravity can realize a specific cosmological evolution, given the mimetic potential and the Lagrange multiplier.
NASA Astrophysics Data System (ADS)
Komsiyah, S.
2014-03-01
The objective in this paper is about economic dispatch problem of electric power generation where scheduling the committed generating units outputs so as to meet the required load demand at minimum operating cost, while satisfying all units and system equality and inequality constraint. In the operating of electric power system, an economic planning problem is one of variables that its must be considered since economically planning will give more efficiency in operational cost. In this paper the economic dispatch problem which has non linear cost function solved by using swarm intelligent method is Gaussian Particle Swarm Optimization (GPSO) and Lagrange Multiplier. GPSO is a population-based stochastic algorithms which their moving inspired by swarm intelligent and probabilities theories. To analize its accuracy, the economic dispatch solution by GPSO method will be compared with Lagrange multiplier method. From the running test result the GPSO method give economically planning calculation which it better than Lagrange multiplier method and the GPSO method faster to getting error convergence. Therefore the GPSO method have better performance to getting global best solution than the Lagrange method.
Pember, R.B.; Anderson, R.W.
2000-11-22
We present a comparison of two algorithms for solving the equations of unsteady inviscid compressible flow in a Eulerian frame. The first algorithm is a staggered grid Lagrange plus remap scheme. The Lagrange step in this method is a time-centered version of the scheme due to Tipton, while the remap step employs a variant of the corner transport upwind scheme due to Colella. The second algorithm is a spatially operator-split version of the higher-order Godunov scheme for gas dynamics due to Colella. They use the two methods to compute solutions to a number of one- and two-dimensional problems. The results show the accuracy and performance of the two schemes to be generally equivalent. In a 1984 survey paper by Woodward and Colella, staggered grid, Lagrange plus remap, artificial viscosity schemes did not compare favorably with cell-centered direct Eulerian higher-order Godunov methods. They examine, therefore, how certain features of the staggered grid scheme discussed here contribute to its improved accuracy. They show in particular that the improved accuracy of the present scheme is due in part to the use of a monotonic artificial viscosity in the Lagrange step and the use of an improved upwind method in the remap step.
Pivotal Roles of T-Helper 17-Related Cytokines, IL-17, IL-22, and IL-23, in Inflammatory Diseases
Qu, Ning; Xu, Mingli; Mizoguchi, Izuru; Furusawa, Jun-ichi; Kaneko, Kotaro; Watanabe, Kazunori; Mizuguchi, Junichiro; Itoh, Masahiro; Kawakami, Yutaka; Yoshimoto, Takayuki
2013-01-01
T-helper 17 (Th17) cells are characterized by producing interleukin-17 (IL-17, also called IL-17A), IL-17F, IL-21, and IL-22 and potentially TNF-α and IL-6 upon certain stimulation. IL-23, which promotes Th17 cell development, as well as IL-17 and IL-22 produced by the Th17 cells plays essential roles in various inflammatory diseases, such as experimental autoimmune encephalomyelitis, rheumatoid arthritis, colitis, and Concanavalin A-induced hepatitis. In this review, we summarize the characteristics of the functional role of Th17 cells, with particular focus on the Th17 cell-related cytokines such as IL-17, IL-22, and IL-23, in mouse models and human inflammatory diseases. PMID:23956763
Anti–IL-6 neutralizing antibody modulates blood-brain barrier function in the ovine fetus
Zhang, Jiyong; Sadowska, Grazyna B.; Chen, Xiaodi; Park, Seon Yeong; Kim, Jeong-Eun; Bodge, Courtney A.; Cummings, Erin; Lim, Yow-Pin; Makeyev, Oleksandr; Besio, Walter G.; Gaitanis, John; Banks, William A.; Stonestreet, Barbara S.
2015-01-01
Impaired blood-brain barrier function represents an important component of hypoxic-ischemic brain injury in the perinatal period. Proinflammatory cytokines could contribute to ischemia-related blood-brain barrier dysfunction. IL-6 increases vascular endothelial cell monolayer permeability in vitro. However, contributions of IL-6 to blood-brain barrier abnormalities have not been examined in the immature brain in vivo. We generated pharmacologic quantities of ovine-specific neutralizing anti-IL-6 mAbs and systemically infused mAbs into fetal sheep at 126 days of gestation after exposure to brain ischemia. Anti–IL-6 mAbs were measured by ELISA in fetal plasma, cerebral cortex, and cerebrospinal fluid, blood-brain barrier permeability was quantified using the blood-to-brain transfer constant in brain regions, and IL-6, tight junction proteins, and plasmalemma vesicle protein (PLVAP) were detected by Western immunoblot. Anti–IL-6 mAb infusions resulted in increases in mAb (P < 0.05) in plasma, brain parenchyma, and cerebrospinal fluid and decreases in brain IL-6 protein. Twenty-four hours after ischemia, anti–IL-6 mAb infusions attenuated ischemia-related increases in blood-brain barrier permeability and modulated tight junction and PLVAP protein expression in fetal brain. We conclude that inhibiting the effects of IL-6 protein with systemic infusions of neutralizing antibodies attenuates ischemia-related increases in blood-brain barrier permeability by inhibiting IL-6 and modulates tight junction proteins after ischemia.—Zhang, J., Sadowska, G. B., Chen, X., Park, S. Y., Kim, J.-E., Bodge, C. A., Cummings, E., Lim, Y.-P., Makeyev, O., Besio, W. G., Gaitanis, J., Banks, W. A., Stonestreet, B. S. Anti–IL-6 neutralizing antibody modulates blood-brain barrier function in the ovine fetus. PMID:25609424
IL-4 and IL-13 Inhibition in Atopic Dermatitis.
Matsunaga, Matthew C; Yamauchi, Paul S
2016-08-01
Atopic dermatitis (AD) is a chronic, prevalent, multi-factorial condition that affects infants, children, and adults. Beyond topical therapy, a variety of systemic agents such as steroids, methotrexate, cyclosporine, azathioprine, mycophenoloic acid, and other agents are utilized to treat moderate to severe AD. However, these agents are associated with potential long term adverse events and organ toxicity. There is an unmet need for a safer, long-term systemic agent to adequately control moderate to severe AD. The role of the Th2 cytokines, IL-4 and IL-13, in AD has led to the development of biologic agents to treat AD. The aim of this article is to review the role of IL-4 and IL-13 in the pathogenesis of AD and discuss some of the clinical trial data that target and inhibit IL-4 and IL-13 in positively altering the course and outcome of AD.
J Drugs Dermatol. 2016;15(8):925-929. PMID:27537991
Effects of Park Improvements on Park Use and Physical Activity Policy and Programming Implications
Cohen, Deborah; Golinelli, Daniela; Williamson, Stephanie; Sehgal, Amber; Marsh, Terry; McKenzie, Thomas L
2009-01-01
Background Many assume that improving the quality and the perceived safety of facilities in parks and recreation centers are critical to attracting more users and increasing population physical activity. There are few studies in which these assumptions have been tested. Purpose To assess the impact of park improvements on park use and physical activity. Methods Five intervention parks and five matched comparison parks were studied by objectively measuring park use and collecting self reports of park use by residents before and after park improvements. After using the System for Observing Play and Recreation in Communities (SOPARC) to count park users and measure their activity levels and conducting household interviews and intercept surveys with park users, propensity score analyses were used to adjust for differences in respondents’ characteristics between pre- and post-intervention and across conditions. Results Overall park use and physical activity declined in both intervention and control parks, with 39% of the decline directly attributable to fewer scheduled organized activities. Perceptions of park safety increased more in the intervention parks than in the comparison parks. Conclusions Improvements to parks may not automatically result in increased use and physical activity, especially when programming decreases. Multiple factors contribute to park use and need to be accounted for in future community-level interventions. Improving perceptions of safety alone are unlikely to result in increased park use. PMID:19944911
Effects of IL-1β, IL-6 and IL-8 on erythrocytes, platelets and clot viscoelasticity
Bester, Janette; Pretorius, Etheresia
2016-01-01
Complex interactions exist between cytokines, and the interleukin family plays a fundamental role in inflammation. Particularly circulating IL-1β, IL-6 and IL-8 are unregulated in systemic and chronic inflammatory conditions. Hypercoagulability is an important hallmark of inflammation, and these cytokines are critically involved in abnormal clot formation, erythrocyte pathology and platelet hyper-activation, and these three cytokines have known receptors on platelets. Although these cytokines are always unregulated in inflammation, we do not know how the individual cytokines act upon the structure of erythrocytes and platelets, and which of the viscoelastic clot parameters are changed. Here we study the effects of IL-1β, IL-6 and IL-8 at low physiological levels, representative of chronic inflammation, by using scanning electron microscopy and thromboelastography. All three interleukins caused the viscoelastic properties to display an increased hypercoagulability of whole blood and pathology of both erythrocytes and platelets. The most pronounced changes were noted where all three cytokines caused platelet hyper-activation and spreading. Erythrocyte structure was notably affected in the presence of IL-8, where the morphological changes resembled that typically seen in eryptosis (programmed cell death). We suggest that erythrocytes and platelets are particularly sensitive to cytokine presence, and that they are excellent health indicators. PMID:27561337
Applications of solar energy in industrial parks
Greaver, V.W.; Farrington, R.B.; Leboeuf, C.M.
1980-05-01
The four phases of ongoing work at SERI that examines many unresolved questions regarding the purpose, solar applicability, economics, and energy modeling of industral parks are presented. The first phase involved site visits to approximately 300 parks in 12 major metropolitan areas of 9 states. Phase 2 entails an analysis of four parks selected from those parks surveyed. Phase 3 narrows the focus to two parks to be examined for detailed technical and engineering analysis. Phase 4 incorporates all of the work of the earlier phases with economic criteria to produce an energy allocation model describing energy delivery and consumption within the park.
Amusement park injuries and deaths.
Braksiek, Robert J; Roberts, David J
2002-01-01
Media coverage of amusement park injuries has increased over the past several years, raising concern that amusement rides may be dangerous. Amusement park fatalities and increases in reported injuries have prompted proposed legislation to regulate the industry. Since 1979, the medical literature has published reports of 4 subdural hematomas, 4 internal carotid artery dissections, 2 vertebral artery dissections, 2 subarachnoid hemorrhages, 1 intraparenchymal hemorrhage, and 1 carotid artery thrombosis with stroke, all related to roller coaster rides. In this article, we review reports of amusement park injuries in the medical literature and Consumer Product Safety Commission data on the overall risk of injury. We also discuss the physics and the physiologic effects of roller coasters that may influence the type and severity of injuries. Although the risk of injury is low, emergency physicians are advised to include participation on thrill rides as part of their history, particularly when evaluating patients presenting with neurologic symptoms. PMID:11782733
Bibliography of Doctor Chul Park
NASA Technical Reports Server (NTRS)
Gochberg, Lawrence A.; Venkatapathy, Ethiraj; Park, Chul
1995-01-01
This document contains a comprehensive bibliography of the published works, and a short biography, of Dr. Chul Park. The contents of this bibliography were compiled primarily from the NASA RECON data base. The RECON citations have been modified to appear in a uniform format with all other listed citations . These other citations were located by computer searches in the INSPEC, NTIS, COMPENDEX, and Chemical Abstracts data bases, as well as through the cooperation of Dr. Chul Park, and his associates in the Reacting Flow Environments Branch at NASA Ames Research Center. All citations are presented in an approximate reverse chronological order from the present date. This work was created to honor the occasion of Dr. Chul Park's retirement on December 14, 1994, after 27 years of distinguished government service at the NASA Ames Research Center.
Kapelski, Pawel; Skibinska, Maria; Maciukiewicz, Malgorzata; Wilkosc, Monika; Frydecka, Dorota; Groszewska, Agata; Narozna, Beata; Dmitrzak-Weglarz, Monika; Czerski, Piotr; Pawlak, Joanna; Rajewska-Rager, Aleksandra; Leszczynska-Rodziewicz, Anna; Slopien, Agnieszka; Zaremba, Dorota; Twarowska-Hauser, Joanna
2015-12-01
Schizophrenia has been associated with a large range of autoimmune diseases, with a history of any autoimmune disease being associated with a 45% increase in risk for the illness. The inflammatory system may trigger or modulate the course of schizophrenia through complex mechanisms influencing neurodevelopment, neuroplasticity and neurotransmission. In particular, increases or imbalance in cytokine before birth or during the early stages of life may affect neurodevelopment and produce vulnerability to the disease. A total of 27 polymorphisms of IL1N gene: rs1800587, rs17561; IL1B gene: rs1143634, rs1143643, rs16944, rs4848306, rs1143623, rs1143633, rs1143627; IL1RN gene: rs419598, rs315952, rs9005, rs4251961; IL6 gene: rs1800795, rs1800797; IL6R gene: rs4537545, rs4845617, rs2228145, IL10 gene: rs1800896, rs1800871, rs1800872, rs1800890, rs6676671; IL10RA gene: rs2229113, rs3135932; TGF1B gene: rs1800469, rs1800470; each selected on the basis of molecular evidence for functionality, were investigated in this study. Analysis was performed on a group of 621 patients with diagnosis of schizophrenia and 531 healthy controls in Polish population. An association of rs4848306 in IL1B gene, rs4251961 in IL1RN gene, rs2228145 and rs4537545 in IL6R with schizophrenia have been observed. rs6676671 in IL10 was associated with early age of onset. Strong linkage disequilibrium was observed between analyzed polymorphisms in each gene, except of IL10RA. We observed that haplotypes composed of rs4537545 and rs2228145 in IL6R gene were associated with schizophrenia. Analyses with family history of schizophrenia, other psychiatric disorders and alcohol abuse/dependence did not show any positive findings. Further studies on larger groups along with correlation with circulating protein levels are needed. PMID:26481614
Dickson, E.M.; Loperena, G.A.
1984-08-01
The purpose of this project was to survey the status of wind parks owned by non-utility organizations which generate electricity for sale to electric utilities under the provisions of the Public Utility Regulatory Policies Act. Both technical (including wind turbine descriptions) and business-related information were gathered from over 100 wind park developers who were interviewed by telephone or in person. Following the survey, the wind parks were screened so that only those already on-line or with very good possibilities of coming on-line by mid-1984 were included. This screening, although subject to judgment, was based primarily on the status of several of the critical milestones necessary for project completion. This document includes descriptions of 85 wind parks established by over 60 developers. Of these, 73 are located in California. This concentration in California is the result of the confluence of tax advantages, financial, institutional, and resource factors currently most favorably found in that state. For the wind parks described in this document, installed generating capacity (based on nameplate ratings) is 87 MW as of July 1983, with plans calling for aggregate installation of some 730 MW by mid-1984. Continued expansion in wind turbine installations over the next several years will require that wind turbines demonstrate high equipment availability with acceptable operating and maintenance costs. If these can be achieved, if the cost effectiveness of the equipment improves by 20%, and if borrowing terms improve, then wind parks could remain economically viable businesses for non-utility owners even after the current tax advantages expire.
IL-17A, IL-22, IL-6, and IL-21 Serum Levels in Plaque-Type Psoriasis in Brazilian Patients.
de Oliveira, Priscilla Stela Santana; Cardoso, Pablo Ramon Gualberto; Lima, Emerson Vasconcelos de Andrade; Pereira, Michelly Cristiny; Duarte, Angela Luzia Branco Pinto; Pitta, Ivan da Rocha; Rêgo, Moacyr Jesus Barreto de Melo; Pitta, Maira Galdino da Rocha
2015-01-01
Psoriasis is a chronic inflammatory skin disease characterized by alterations in cytokines produced by both Th1 and Th17 pathways. The aim of this study was to evaluate serum levels of pivotal cytokines and correlate them with clinical parameters. Serum samples from 53 psoriasis patients and 35 healthy volunteers, matched by the proportion of sex and age ratios, were collected for ELISA cytokine detection. Psoriasis Area and Severity Index (PASI) was assessed at the time of sampling in psoriasis patients. Our findings demonstrate that IL-17A, IL-22, and IL-6 serum concentrations were significantly higher in psoriasis patients than in the control group. No statistical correlation could be found between cytokines concentrations, PASI score, and age in this study. Although our results do not show any correlation between serum levels of IL-17A, IL-22, and IL-6 and disease activity, the present study confirms that they were increased in Brazilian psoriasis patients in comparison to healthy volunteers. PMID:26351408
IL-17A, IL-22, IL-6, and IL-21 Serum Levels in Plaque-Type Psoriasis in Brazilian Patients
de Oliveira, Priscilla Stela Santana; Cardoso, Pablo Ramon Gualberto; Lima, Emerson Vasconcelos de Andrade; Pereira, Michelly Cristiny; Duarte, Angela Luzia Branco Pinto; Pitta, Ivan da Rocha; Rêgo, Moacyr Jesus Barreto de Melo; Pitta, Maira Galdino da Rocha
2015-01-01
Psoriasis is a chronic inflammatory skin disease characterized by alterations in cytokines produced by both Th1 and Th17 pathways. The aim of this study was to evaluate serum levels of pivotal cytokines and correlate them with clinical parameters. Serum samples from 53 psoriasis patients and 35 healthy volunteers, matched by the proportion of sex and age ratios, were collected for ELISA cytokine detection. Psoriasis Area and Severity Index (PASI) was assessed at the time of sampling in psoriasis patients. Our findings demonstrate that IL-17A, IL-22, and IL-6 serum concentrations were significantly higher in psoriasis patients than in the control group. No statistical correlation could be found between cytokines concentrations, PASI score, and age in this study. Although our results do not show any correlation between serum levels of IL-17A, IL-22, and IL-6 and disease activity, the present study confirms that they were increased in Brazilian psoriasis patients in comparison to healthy volunteers. PMID:26351408
Chen, Guanghui; Liang, Yanfang; Guan, Xin; Chen, Hui; Liu, Qiankun; Lin, Bihua; Chen, Can; Huang, Mingyuan; Chen, Jianan; Wu, Weiquan; Liang, Yi; Zhou, Keyuan; Zeng, Jincheng
2016-01-01
The interleukin (IL)-12 family, composed of heterodimeric cytokines including IL-12 (formed by IL-12p35 and IL-12p40 subunits), IL-23 (formed by IL-23p19 and IL-12p40 subunits), IL-27 (formed by IL-27p28 and EBI3 subunits) and IL-35 (formed by IL-12p35 and EBI3 subunits), establishes a link between innate and adaptive immunity that involves different immune effector cells and cytokines to tumors. However, the role of IL-12 family in breast cancer (BC) progression and prognosis remains unclear. In the present study, we demonstrated evidence indicating that EBI3, IL-12p35 and IL-12p40 but not IL-23p19 or IL-27p28 were highly expressed in BC tissues, suggested that tumor derived EBI3, IL-12p35 and IL-12p40 were associated with tumor progression. Circulating IL-12 and IL-23 low expressed, but IL-27 and IL-35 high expressed in BC patients, especially circulating IL-23 associated with IL-35 to mediate BC tumor resection. Ki-67, p53 and EGFR expression on BC tissues, as well as CA125, CA153 and CA199 levels on BC bloods increased when circulating IL-23: IL-35 ratio decreased. Together, for the first time, our data suggest that circulating IL-23: IL-35 ratio may be an important indicator association with BC progression and prognosis. However, further research should be carried out to assess the implications of circulating IL-23: IL-35 ratio in a larger sample size. PMID:27347332
Everglades National Park Including Biscayne National Park. Activity Book.
ERIC Educational Resources Information Center
Ruehrwein, Dick
Intended to help elementary school children learn about the resources of the Everglades and Biscayne National Parks, this activity book includes information, puzzles, games, and quizzes. The booklet deals with concepts related to: (1) the seasons; (2) fire ecology; (3) water; (4) fish; (5) mammals; (6) mosquitos; (7) birds; (8) venomous snakes;…
Lagrange L4/L5 points and the origin of our Moon and Saturn's moons and rings.
Gott, J Richard
2005-12-01
The current standard theory of the origin of the Moon is that the Earth was hit by a giant impactor the size of Mars causing ejection of debris from its mantle that coalesced to form the moon; but where did this Mars-sized impactor come from? Isotopic evidence suggests that it came from 1 AU radius in the solar nebula, and computer simulations are consistent with its approaching Earth on a zero-energy parabolic trajectory. How could such a large object form at 1 AU in a quiescent disk of planetesimals without having already collided with the Earth at an earlier epoch before having the chance to grow large? Belbruno and Gott propose that the giant impactor could have formed in a stable orbit from debris at the Earth's Lagrange point L(5) (or L(4)). It would grow quietly by accretion at L(5) (or L(4)), but eventually gravitational perturbations by other growing planetesimals would kick it out into a horseshoe orbit and finally into a chaotic creeping orbit, which Belbruno and Gott show would, with high probability, hit the Earth on a near zero-energy parabolic trajectory. We can see other examples of this phenomenon occurring in the solar system. Asteroid 2002AA29 is in a horseshoe orbit relative to the Earth that looks exactly like the horseshoe orbits that Belbruno and Gott found for objects that had been perturbed from L(4)/L(5). The regular moons of Saturn are made of ice and have the same albedo as the ring particles (ice chunks, plus some dust). We (J. R. Gott, R. Vanderbei, and E. Belbruno) propose that the regular icy moons of Saturn (out to the orbit of Titan), which are all in nearly circular orbits, formed out of a thin disk of planetesimals (ice chunks) rather like the rings of Saturn today only larger in extent. In such a situation formation of objects at L(4)/L(5) might be expected. Indeed, Saturn's moon Dione is accompanied by moons (Helene and Polydeuces) at both L(4) and L(5) Lagrange points, and Saturn's moon Tethys is also accompanied by moons
Lichens of the U. S. national parks
Bennett, J.P.; Wetmore, C.M.
2005-01-01
Over 26,100 records of lichens present in 144 U.S. national park units were assembled from various sources into a database and analyzed. Within these 144 park units 2,435 species and 375 genera are reported, representing 63% and 74% of the North American flora, respectively. The park units are located in 41 states and Washington, D.C. The average number of species in a park is 104, but the median is 60, indicating there are many parks with a small number of species and a few with high numbers. Isle Royale National Park has the most species, 611, and twelve parks have only one species reported. The number of records of lichens present ranged from one for 25 parks, to 1,623 for Isle Royale. Physcia aipolia is the most frequently observed species, being found in 65 parks. One fourth of the park units are classified cultural resource parks, while the remainder are considered natural resource parks. This study was based on 453 sources, including literature citations, park reports and collections in the University of Minnesota Herbarium. Copyright ?? 2005 by the American Bryological and Lichenological Society, Inc.
Quantitative Contribution of IL2Rγ to the Dynamic Formation of IL2-IL2R Complexes
Ponce, Luis F.; García-Martínez, Karina; León, Kalet
2016-01-01
Interleukin-2 (IL2) is a growth factor for several immune cells and its function depends on its binding to IL2Rs in the cell membrane. The most accepted model for the assembling of IL2-IL2R complexes in the cell membrane is the Affinity Conversion Model (ACM). This model postulates that IL2R receptor association is sequential and dependent on ligand binding. Most likely free IL2 binds first to IL2Rα, and then this complex binds to IL2Rβ, and finally to IL2Rγ (γc). However, in previous mathematical models representing this process, the binding of γc has not been taken into account. In this work, the quantitative contribution of the number of IL2Rγ chain to the IL2-IL2R apparent binding affinity and signaling is studied. A mathematical model of the affinity conversion process including the γ chain in the dynamic, has been formulated. The model was calibrated by fitting it to experimental data, specifically, Scatchard plots obtained using human cell lines. This paper demonstrates how the model correctly explains available experimental observations. It was estimated, for the first time, the value of the kinetic coefficients of IL2-IL2R complexes interaction in the cell membrane. Moreover, the number of IL2R components in different cell lines was also estimated. It was obtained a variable distribution in the number of IL2R components depending on the cell type and the activation state. Of most significance, the study predicts that not only the number of IL2Rα and IL2Rβ, but also the number of γc determine the capacity of the cell to capture and retain IL2 in signalling complexes. Moreover, it is also showed that different cells might use different pathways to bind IL2 as consequence of its IL2R components distribution in the membrane. PMID:27195783
Code of Federal Regulations, 2011 CFR
2011-07-01
... of existing on- and off-street parking space should be stressed on a nonreserved (first-come, first... by category of eligible parkers. Designation of parking spaces by name, grade, rank, or title...
Injuries At Indoor Trampoline Parks Jump
... news/fullstory_160460.html Injuries at Indoor Trampoline Parks Jump Researchers say finding shows need for safety ... News) -- A wave of injuries at indoor trampoline parks has prompted a call for design and safety ...
Injuries Soar as Trampoline Parks Expand
... news/fullstory_160184.html Injuries Soar as Trampoline Parks Expand Broken bones, fractures the most common complaints ... MONDAY, Aug. 1, 2016 (HealthDay News) -- As trampoline parks spring up across the United States, injuries to ...
Soluble IL7Rα potentiates IL-7 bioactivity and promotes autoimmunity
Lundström, Wangko; Highfill, Steven; Walsh, Scott T. R.; Beq, Stephanie; Morse, Elizabeth; Kockum, Ingrid; Alfredsson, Lars; Olsson, Tomas; Hillert, Jan; Mackall, Crystal L.
2013-01-01
Human soluble interleukin-7 receptor (sIL7R)α circulates in high molar excess compared with IL-7, but its biology remains unclear. We demonstrate that sIL7Rα has moderate affinity for IL-7 but does not bind thymic stromal lymphopoietin. Functionally, sIL7Rα competes with cell-associated IL-7 receptor to diminish excessive IL-7 consumption and, thus, enhances the bioactivity of IL-7 when the cytokine is limited, as it is presumed to be in vivo. IL-7 signaling in the presence of sIL7Rα also diminishes expression of CD95 and suppressor of cytokine signaling 1, both regulatory molecules. Murine models confirm diminished consumption of IL-7 in the presence of sIL7Rα and also demonstrate a potentiating effect of sIL7Rα on IL-7–mediated homeostatic expansion and experimental autoimmune encephalomyelitis exacerbation. In multiple sclerosis and several other autoimmune diseases, IL7R genotype influences susceptibility. We measured increased sIL7Rα levels, as well as increased IL-7 levels, in multiple sclerosis patients with the predisposing IL7R genotype, consistent with diminished IL-7 consumption in vivo. This work demonstrates that sIL7Rα potentiates IL-7 bioactivity and provides a basis to explain the increased risk of autoimmunity observed in individuals with genotype-induced elevations of sIL7Rα. PMID:23610432
ERIC Educational Resources Information Center
Hancock, Karen
2007-01-01
In this article, the author presents a lesson on rotational symmetry which she developed for her students. The aim of the lesson was "to identify objects with rotational symmetry in the staff car park" and the success criteria were "pictures or sketches of at least six objects with different orders of rotation". After finding examples of…
'Shockley park' stirs racism row
NASA Astrophysics Data System (ADS)
Gwynne, Peter
2009-07-01
A local authority in Northern California has encountered unexpected resistance to its decision to name a park after the Nobel-prize-winning physicist William Shockley, with a coalition of churches and civic groups preparing to petition against the name at a meeting scheduled for 23 July.
National Zoological Park Branch Library.
ERIC Educational Resources Information Center
Kenyon, Kay A.
1988-01-01
Describes the functions of the National Zoological Park Branch of the Smithsonian Institution Libraries, which is dedicated to supporting the special information needs of the zoo. Topics covered include the library's history, collection, programs, services, future plans, and relations with other zoo libraries. (two references) (Author/CLB)
UV - RESEARCH TRIANGLE PARK NC
Brewer 087 is located in Research Triangle Park NC, measuring ultraviolet solar radiation. Irradiance and column ozone are derived from this data. Ultraviolet solar radiation is measured with a Brewer Mark IV, single-monochrometer, spectrophotometer manufactured by SCI-TEC Instru...
Egmont National Park, New Zealand
NASA Technical Reports Server (NTRS)
2002-01-01
The lush forests of Egmont National Park, on New Zealand's North Island, contrast with the pasturelands outside the circular park boundaries. The unique shape of the park results from its first protection in 1881, which specified that a forest reserve would extend in a 9.6 km radius from the summit of Mt. Taranaki (named Mt. Egmont by Captain Cook). The park covers about 33,500 hectares and Mt. Egmont stands at 2518 m. The volcano began forming 70,000 years ago, and last erupted in 1755. A series of montane habitats occur in procession up the flanks of the volcano-from rainforest, to shrubs, to alpine, and finally snow cover. Image STS110-726-6, was taken by Space Shuttle crewmembers on 9 April 2002 using a Hasselblad film camera. Image provided by the Earth Sciences and Image Analysis Laboratory at Johnson Space Center. Additional images taken by astronauts and cosmonauts can be viewed at the NASA-JSC Gateway to Astronaut Photography of Earth.
Coltsville National Historical Park Act
Sen. Lieberman, Joseph I. [ID-CT
2011-07-12
10/19/2011 Committee on Energy and Natural Resources Subcommittee on National Parks. Hearings held. With printed Hearing: S.Hrg. 112-224. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:
Coltsville National Historical Park Act
Sen. Blumenthal, Richard [D-CT
2013-03-19
04/23/2013 Committee on Energy and Natural Resources Subcommittee on National Parks. Hearings held. With printed Hearing: S.Hrg. 113-27. (All Actions) Notes: For further action, see H.R.3979, which became Public Law 113-291 on 12/19/2014. Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:
Code of Federal Regulations, 2012 CFR
2012-07-01
... INVESTIGATIONS MOTOR VEHICLE TRAFFIC SUPERVISION Traffic Supervision § 634.31 Parking. (a) The most efficient use of existing on- and off-street parking space should be stressed on a nonreserved (first-come, first... 32 National Defense 4 2012-07-01 2011-07-01 true Parking. 634.31 Section 634.31 National...
Code of Federal Regulations, 2012 CFR
2012-10-01
... 49 Transportation 5 2012-10-01 2012-10-01 false Parking. 397.7 Section 397.7 Transportation Other... PARKING RULES General § 397.7 Parking. (a) A motor vehicle which contains Division 1.1, 1.2, or 1.3... traveled portion of a public street or highway; (2) On private property (including premises of fueling...
Code of Federal Regulations, 2013 CFR
2013-07-01
... INVESTIGATIONS MOTOR VEHICLE TRAFFIC SUPERVISION Traffic Supervision § 634.31 Parking. (a) The most efficient use of existing on- and off-street parking space should be stressed on a nonreserved (first-come, first... 32 National Defense 4 2013-07-01 2013-07-01 false Parking. 634.31 Section 634.31 National...
Code of Federal Regulations, 2014 CFR
2014-07-01
... INVESTIGATIONS MOTOR VEHICLE TRAFFIC SUPERVISION Traffic Supervision § 634.31 Parking. (a) The most efficient use of existing on- and off-street parking space should be stressed on a nonreserved (first-come, first... 32 National Defense 4 2014-07-01 2013-07-01 true Parking. 634.31 Section 634.31 National...
Code of Federal Regulations, 2014 CFR
2014-10-01
... 49 Transportation 5 2014-10-01 2014-10-01 false Parking. 397.7 Section 397.7 Transportation Other... PARKING RULES General § 397.7 Parking. (a) A motor vehicle which contains Division 1.1, 1.2, or 1.3... traveled portion of a public street or highway; (2) On private property (including premises of fueling...
Moon Park: A research and educational facility
NASA Technical Reports Server (NTRS)
Kuriki, Kyoichi; Saito, Takao; Ogawa, Yukimasa
1992-01-01
Moon Park has been proposed as an International Space Year (ISY) event for international cooperative efforts. Moon Park will serve as a terrestrial demonstration of a prototype lunar base and provide research and educational opportunities. The kind of data that can be obtained in the Moon Park facilities is examined taking the minimum number of lunar base residents as an example.
What's Ahead for our National Parks?
ERIC Educational Resources Information Center
George, Jean Craighead
1972-01-01
To insure the future of our National Parks, sweeping changes must be made. Encroaching civilization at the expense of nature has forced National Park officials to consider alternatives to future development - limiting number of visitors, facilities outside the parks and curtailing vehicular traffic. (BL)
75 FR 12254 - National Park Service
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-15
... National Park Service AGENCY: National Park Service, U.S. Department of the Interior. ACTION: National... National Center for Preservation Technology and Training, National Park Service, will meet on Thursday and... amended, (16 U.S.C. 470x-2(e)). The PTTBoard will meet at Lee H. Nelson Hall, the headquarters of...
Code of Federal Regulations, 2012 CFR
2012-04-01
... 23 Highways 1 2012-04-01 2012-04-01 false Parking. 1235.6 Section 1235.6 Highways NATIONAL HIGHWAY TRAFFIC SAFETY ADMINISTRATION AND FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION GUIDELINES UNIFORM SYSTEM FOR PARKING FOR PERSONS WITH DISABILITIES § 1235.6 Parking. Special license plates, removable windshield placards, or...
"The Rosa Parks Story": Guide for Educators.
ERIC Educational Resources Information Center
Onish, Liane B.
On December 1, 1955, Rosa Parks, a black seamstress, refused to give up her seat to a white man on a public bus in Montgomery, Alabama, and she was arrested. On that day, Rosa Parks became the mother of the modern civil rights movement. This study guide may be used as a companion to "The Rosa Parks Story" video which aired on CBS television…
77 FR 24575 - National Park Week, 2012
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-25
... Independence of the United States of America the two hundred and thirty-sixth. (Presidential Sig.) [FR Doc... Documents#0;#0; #0; #0;Title 3-- #0;The President ] Proclamation 8801 of April 20, 2012 National Park Week... National Park Week, all 397 National Parks will offer free admission from April 21 through April 29,...
76 FR 22001 - National Park Week, 2011
Federal Register 2010, 2011, 2012, 2013, 2014
2011-04-20
... the two hundred and thirty-fifth. (Presidential Sig.) [FR Doc. 2011-9730 Filed 4-19-11; 8:45 am... Documents#0;#0; ] Proclamation 8656 of April 15, 2011 National Park Week, 2011 By the President of the.... ``Healthy Parks, Healthy People,'' the focus for this year's National Park Week, highlights the role...
MOLECULAR AND FUNCTIONAL CHARACTERIZATIONS OF IL-17
Technology Transfer Automated Retrieval System (TEKTRAN)
In mammals, the IL-17 family of cytokines (IL-17A-F) has a very distinct expression pattern and a different biological function. IL-17 is mainly secreted by activated CD4+ T cells and has been implicated in autoimmune and inflammatory diseases. IL-17 has been shown to exert an important role in host...
NASA Astrophysics Data System (ADS)
Bish, Robert Leonard
2016-06-01
The paper presents a variational principle based on a new physical law governing the rotationally continuous flow of a solid that flows by means of the recently identified mechanism of extended slip. The Euler-Lagrange equations derived from this principle are applied to the plane torsion problem. Theoretical results so obtained are compared to experimental measurements made using discs of cold-worked aluminium, and excellent agreement between experiment and theory is obtained. Interesting properties of plane torsion are revealed by this investigation. It is shown, for instance, that within the shear annulus in the disc, at each stage of its expansion, the rotation rate is independent of position. Moreover, if we consider the disc centre to be rotating relative to its edge, the rotation rate in the shear annulus is opposite to that in the rigid centre of the disc. At each stage, not only are the senses of rotation of the disc centre and the shear annulus opposite but the products of rotation rate and area for the two domains remain equal.
Felippa, Carlos A.; Sprague, Michael A.; Ross, Michael R.; Park, K. C.
2008-11-01
This paper is a sequel on the topic of localized Lagrange multipliers (LLM) for applications of fluid-structure interaction (FSI) between finite-element models of an acoustic fluid and an elastic structure. The prequel paper formulated the spatial-discretization methods, the LLM interface treatment, the time-marching partitioned analysis procedures, and the application to 1D benchmark problems. Here, we expand on formulation aspects required for successful application to more realistic 2D and 3D problems. Additional topics include duality relations at the fluid-structure interface, partitioned vibration analysis, reduced-order modeling, handling of curved interface surfaces, and comparison of LLM with other coupling methods. Emphasis is given to non-matching fluid-structure meshes. We present benchmark examples that illustrate the benefits and drawbacks of competing interface treatments. Realistic application problems involving the seismic response of two existing dams are considered. These include 2D modal analyses of the Koyna gravity dam, transient-response analyses of that dam with and without reduced-order modeling, incorporation of nonlinear cavitation effects, and the 3D transient-response analysis of the Morrow Point arch dam.
NASA Astrophysics Data System (ADS)
Bokil, Vrushali A.; Glowinski, Roland
2005-05-01
We propose a novel fictitious domain method based on a distributed Lagrange multiplier technique for the solution of the time-dependent problem of scattering by an obstacle. We study discretizations that include a fully conforming approach as well as mixed finite element formulations utilizing the lowest order Nédélec edge elements (in 2D) on rectangular grids. We also present a symmetrized operator splitting scheme for the scattering problem, which decouples the operator that propagates the wave from the operator that enforces the Dirichlet condition on the boundary of an obstacle. A new perfectly matched layer (PML) model is developed to model the unbounded problem of interest. This model is based on a formulation of the wave equation as a system of first-order equations and uses a change of variables approach that has been developed to construct PML's for Maxwell's equations. We present an analysis of our fictitious domain approach for a one-dimensional wave problem. Based on calculations of reflection coefficients, we demonstrate the advantages of our fictitious domain approach over the staircase approximation of the finite difference method. We also demonstrate some important properties of the distributed multiplier approach that are not shared by a boundary multiplier fictitious domain approach for the same problem. Numerical results for two-dimensional wave problems that validate the effectiveness of the different methods are presented.
NASA Technical Reports Server (NTRS)
Nguyen, Louis H.; Ramakrishnan, Jayant; Granda, Jose J.
2006-01-01
The assembly and operation of the International Space Station (ISS) require extensive testing and engineering analysis to verify that the Space Station system of systems would work together without any adverse interactions. Since the dynamic behavior of an entire Space Station cannot be tested on earth, math models of the Space Station structures and mechanical systems have to be built and integrated in computer simulations and analysis tools to analyze and predict what will happen in space. The ISS Centrifuge Rotor (CR) is one of many mechanical systems that need to be modeled and analyzed to verify the ISS integrated system performance on-orbit. This study investigates using Bond Graph modeling techniques as quick and simplified ways to generate models of the ISS Centrifuge Rotor. This paper outlines the steps used to generate simple and more complex models of the CR using Bond Graph Computer Aided Modeling Program with Graphical Input (CAMP-G). Comparisons of the Bond Graph CR models with those derived from Euler-Lagrange equations in MATLAB and those developed using multibody dynamic simulation at the National Aeronautics and Space Administration (NASA) Johnson Space Center (JSC) are presented to demonstrate the usefulness of the Bond Graph modeling approach for aeronautics and space applications.
NASA Technical Reports Server (NTRS)
Wong, Hong; Kapila, Vikram
2004-01-01
In this paper, we present a method for trajectory generation and adaptive full-state feedback control to facilitate spacecraft formation flying near the Sun-Earth L2 Lagrange point. Specifically, the dynamics of a spacecraft in the neighborhood of a Halo orbit reveals that there exist quasi-periodic orbits surrounding the Halo orbit. Thus, a spacecraft formation is created by placing a leader spacecraft on a desired Halo orbit and placing follower spacecraft on desired quasi-periodic orbits. To produce a formation maintenance controller, we first develop the nonlinear dynamics of a follower spacecraft relative to the leader spacecraft. We assume that the leader spacecraft is on a desired Halo orbit trajectory and the follower spacecraft is to track a desired quasi-periodic orbit surrounding the Halo orbit. Then, we design an adaptive, full-state feedback position tracking controller for the follower spacecraft providing an adaptive compensation for the unknown mass of the follower spacecraft. The proposed control law is simulated for the case of the leader and follower spacecraft pair and is shown to yield global, asymptotic convergence of the relative position tracking errors.
Production of IL-13 in spleen cells by IL-18 and IL-12 through generation of NK-like cells.
Ueda, Haruyasu; Kashiwamura, Shin-ichiro; Sekiyama, Atsuo; Ogura, Takeharu; Gamachi, Naomi; Okamura, Haruki
2006-02-21
Treatment of Nylon wool-passed cells (NWC) prepared from the spleen of C57BL/6 mice with IL-18 and IL-12, but not with IL-18 alone, resulted in induction of IFN-gamma, a Th1 cytokine, and GM-CSF at 24 h, and IL-13, a Th2 cytokine at 72 h. The induction of IL-13 was suppressed by anti-GM-CSF antibody, indicating involvement of GM-CSF in IL-13 production. When NWC incubated with IL-18 and IL-12 for 72 h ("primary treatment") were treated again with the same cytokines ("secondary treatment"), IL-13 was induced much more quickly than observed in the primary treatment. Flow cytometric analysis of NWC after the primary treatment showed marked increases in the CD4(-)CD8(-) non-T cell population bearing CD25(+), CD45RB(super high) and CD122(+). These cells were positive for CD49b but negative for NK1.1, indicating that they were not typical but NK-like cells. The NK-like cells produced IL-13 in response to the treatment with IL-18 alone, indicating that the generation of these cells in the primary treatment likely accounts for the quick production of IL-13 in the secondary treatment. These results show that IL-18 and IL-12 generates the NK-like cells in NWC by a process mediated by GM-CSF that are ready for producing IL-13. PMID:16549365
Soluble IL-1RII and IL-18 are associated with incipient upper extremity soft tissue disorders.
Rechardt, Martti; Shiri, Rahman; Matikainen, Sampsa; Viikari-Juntura, Eira; Karppinen, Jaro; Alenius, Harri
2011-05-01
Previous studies suggest a role for IL-1β in the pathophysiology of upper extremity soft tissue disorders (UESTDs). We studied the levels of interleukin-1 family members in patients with incipient UESTDs and compared them with healthy controls. In this case control study, we included 163 patients with UESTDs and symptom duration shorter than 1 month and 42 healthy controls matched for age and gender at the group level. Serum levels of cytokines IL-1α, IL-1β, IL-1Ra, IL-6, IL-8, IL-18, IL-33, TNFα and sensitized C-reactive protein as well as IL-1 family soluble receptors sIL-1RII and sST2 were assessed. We used unconditional logistic regression models to study the associations between cytokines and UESTDs. After adjustment for potential confounders, the serum levels of sIL-1RII (p<0.001) and sST2 (p=0.014) were higher in the patients than the controls. The level of IL-18 was lower in the patients than the controls (p=0.005). There were no significant differences between the patients and controls regarding the levels of IL-1α, IL-1β, IL-1Ra, IL-33, IL-6, IL-8, TNFα, or sensitized C-reactive protein. The levels of circulating sIL-1RII and IL-18 are associated with incipient UESTDs, suggesting an important role for these IL-1 family members in the early course of UESTDs. PMID:21371906
IL-18 and Cutaneous Inflammatory Diseases
Lee, Ji hyun; Cho, Dae Ho; Park, Hyun Jeong
2015-01-01
Interleukin (IL)-18, an IL-1 family cytokine, is a pleiotropic immune regulator. IL-18 plays a strong proinflammatory role by inducing interferon (IFN)-γ. Previous studies have implicated IL-18 in the pathogenesis of various diseases. However, it is not well understood biologic activities of IL-18 in the diverse skin diseases. Here, we have reviewed the expression and function of IL-18 in skin diseases including inflammatory diseases. This article provides an evidence-based understanding of the role of IL-18 in skin diseases and its relationship with disease activities. PMID:26690141
36 CFR 7.22 - Grand Teton National Park.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 36 Parks, Forests, and Public Property 1 2011-07-01 2011-07-01 false Grand Teton National Park. 7.22 Section 7.22 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.22 Grand Teton National Park. (a) Aircraft—Designated airstrip. (1) Jackson...
36 CFR 7.41 - Big Bend National Park.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 36 Parks, Forests, and Public Property 1 2014-07-01 2014-07-01 false Big Bend National Park. 7.41 Section 7.41 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.41 Big Bend National Park. (a) Fishing; closed...
76 FR 72003 - Paterson Great Falls National Historical Park
Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-21
... National Park Service Paterson Great Falls National Historical Park AGENCY: National Park Service, Interior... National Historical Park as a unit of the National Park System. FOR FURTHER INFORMATION CONTACT: Gay...: (b) PATERSON GREAT FALLS NATIONAL HISTORICAL PARK.-- (1) ESTABLISHMENT.-- (A) IN GENERAL.--Subject...
36 CFR 7.78 - Harpers Ferry National Historical Park.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 36 Parks, Forests, and Public Property 1 2013-07-01 2013-07-01 false Harpers Ferry National Historical Park. 7.78 Section 7.78 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF... Historical Park. (a) All persons shall register at park headquarters before climbing any portion of the...
36 CFR 7.78 - Harpers Ferry National Historical Park.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 36 Parks, Forests, and Public Property 1 2014-07-01 2014-07-01 false Harpers Ferry National Historical Park. 7.78 Section 7.78 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF... Historical Park. (a) All persons shall register at park headquarters before climbing any portion of the...
36 CFR 7.78 - Harpers Ferry National Historical Park.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 36 Parks, Forests, and Public Property 1 2012-07-01 2012-07-01 false Harpers Ferry National Historical Park. 7.78 Section 7.78 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF... Historical Park. (a) All persons shall register at park headquarters before climbing any portion of the...
36 CFR 7.78 - Harpers Ferry National Historical Park.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Harpers Ferry National Historical Park. 7.78 Section 7.78 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF... Historical Park. (a) All persons shall register at park headquarters before climbing any portion of the...
36 CFR 7.78 - Harpers Ferry National Historical Park.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 36 Parks, Forests, and Public Property 1 2011-07-01 2011-07-01 false Harpers Ferry National Historical Park. 7.78 Section 7.78 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF... Historical Park. (a) All persons shall register at park headquarters before climbing any portion of the...
36 CFR 7.27 - Dry Tortugas National Park.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Dry Tortugas National Park. 7.27 Section 7.27 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.27 Dry Tortugas National Park. (a) What terms do I need to know? The...
36 CFR 7.16 - Yosemite National Park.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 36 Parks, Forests, and Public Property 1 2012-07-01 2012-07-01 false Yosemite National Park. 7.16 Section 7.16 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.16 Yosemite National Park. (a) Fishing—(1) Open season and limit of catch. The open...
36 CFR 7.3 - Glacier National Park.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 36 Parks, Forests, and Public Property 1 2012-07-01 2012-07-01 false Glacier National Park. 7.3 Section 7.3 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.3 Glacier National Park. (a) Fishing. (1) Fishing regulations, based on management...
36 CFR 7.28 - Olympic National Park.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 36 Parks, Forests, and Public Property 1 2012-07-01 2012-07-01 false Olympic National Park. 7.28 Section 7.28 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.28 Olympic National Park. (a) Fishing—(1) General Provisions. All waters within...
36 CFR 7.7 - Rocky Mountain National Park.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 36 Parks, Forests, and Public Property 1 2013-07-01 2013-07-01 false Rocky Mountain National Park. 7.7 Section 7.7 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.7 Rocky Mountain National Park....
36 CFR 7.37 - Jean Lafitte National Historical Park.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 36 Parks, Forests, and Public Property 1 2012-07-01 2012-07-01 false Jean Lafitte National Historical Park. 7.37 Section 7.37 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.37 Jean Lafitte National Historical Park. (a) Fishing. (1) Unless...
36 CFR 7.37 - Jean Lafitte National Historical Park.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 36 Parks, Forests, and Public Property 1 2014-07-01 2014-07-01 false Jean Lafitte National Historical Park. 7.37 Section 7.37 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.37 Jean Lafitte National Historical Park. (a) Fishing. (1) Unless...
36 CFR 7.33 - Voyageurs National Park.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 36 Parks, Forests, and Public Property 1 2011-07-01 2011-07-01 false Voyageurs National Park. 7.33 Section 7.33 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.33 Voyageurs National Park. (a) Fishing. Unless otherwise designated, fishing in a...
36 CFR 7.5 - Mount Rainier National Park.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 36 Parks, Forests, and Public Property 1 2013-07-01 2013-07-01 false Mount Rainier National Park. 7.5 Section 7.5 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.5 Mount Rainier National Park. (a) Fishing. (1) The following waters are closed...
36 CFR 7.4 - Grand Canyon National Park.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Park. The National Park Service reserves the right to limit the number of such permits issued, or the... 36 Parks, Forests, and Public Property 1 2011-07-01 2011-07-01 false Grand Canyon National Park. 7.4 Section 7.4 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE...
36 CFR 7.4 - Grand Canyon National Park.
Code of Federal Regulations, 2014 CFR
2014-07-01
... Park. The National Park Service reserves the right to limit the number of such permits issued, or the... 36 Parks, Forests, and Public Property 1 2014-07-01 2014-07-01 false Grand Canyon National Park. 7.4 Section 7.4 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE...
36 CFR 7.4 - Grand Canyon National Park.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 36 Parks, Forests, and Public Property 1 2012-07-01 2012-07-01 false Grand Canyon National Park. 7.4 Section 7.4 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.4 Grand Canyon National Park. (a) Commercial passenger-carrying motor vehicles....
36 CFR 7.4 - Grand Canyon National Park.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Grand Canyon National Park. 7.4 Section 7.4 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.4 Grand Canyon National Park. (a) Commercial passenger-carrying motor vehicles....
36 CFR 7.39 - Mesa Verde National Park.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 36 Parks, Forests, and Public Property 1 2014-07-01 2014-07-01 false Mesa Verde National Park. 7.39 Section 7.39 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.39 Mesa Verde National Park. (a) Visiting...
36 CFR 7.44 - Canyonlands National Park.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 36 Parks, Forests, and Public Property 1 2011-07-01 2011-07-01 false Canyonlands National Park. 7.44 Section 7.44 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.44 Canyonlands National Park. (a)...
36 CFR 7.10 - Zion National Park.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 36 Parks, Forests, and Public Property 1 2013-07-01 2013-07-01 false Zion National Park. 7.10 Section 7.10 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.10 Zion National Park. (a) Vehicle convoy requirements....
36 CFR 7.15 - Shenandoah National Park.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Shenandoah National Park. 7.15 Section 7.15 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.15 Shenandoah National Park. (a)...
36 CFR 7.4 - Grand Canyon National Park.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 36 Parks, Forests, and Public Property 1 2013-07-01 2013-07-01 false Grand Canyon National Park. 7.4 Section 7.4 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.4 Grand Canyon National Park. (a)...
36 CFR 1253.2 - National Archives at College Park.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false National Archives at College Park. 1253.2 Section 1253.2 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS... College Park. (a) The National Archives at College Park is located at 8601 Adelphi Road, College Park,...
36 CFR 7.38 - Isle Royale National Park.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 36 Parks, Forests, and Public Property 1 2011-07-01 2011-07-01 false Isle Royale National Park. 7.38 Section 7.38 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.38 Isle Royale National Park. (a)...
36 CFR 7.54 - Theodore Roosevelt National Park.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 36 Parks, Forests, and Public Property 1 2012-07-01 2012-07-01 false Theodore Roosevelt National Park. 7.54 Section 7.54 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.54 Theodore Roosevelt National Park....
36 CFR 7.11 - Saguaro National Park.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 36 Parks, Forests, and Public Property 1 2012-07-01 2012-07-01 false Saguaro National Park. 7.11 Section 7.11 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.11 Saguaro National Park. (a) Bicycles. That portion of...