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1

Cuidados paliativos durante el cáncer  

Cancer.gov

Hoja informativa que describe la función de los cuidados paliativos, los cuales son los cuidados que se brindan a pacientes que tienen una enfermedad grave o potencialmente letal, como el cáncer, desde el momento del diagnóstico y durante todo el curso de la enfermedad.

2

Primary Lateral Sclerosis  

MedlinePLUS

NINDS Primary Lateral Sclerosis Information Page Table of Contents (click to jump to sections) What is Primary Lateral Sclerosis? ... is being done? Clinical Trials Organizations What is Primary Lateral Sclerosis? Primary lateral sclerosis (PLS) is a ...

3

ATIVIDADE ANTIMICROBIANA DE Jacaranda mimosaefolia D. DON  

Microsoft Academic Search

RESUMO: Foram realizados ensaios microbiológicos para avaliar a atividade antibacteriana e antifúngica do extrato aquoso de folhas de Jacaranda mimosaefolia D. Don, contra quatro diferentes microrganismos. O extrato aquoso apresentou resultados significativos frente a Staphylococcus aureus ATCC 6538P, Staphylococcus epidermidis ATCC 12128, Escherichia coli ATCC 10536 e contra Saccharomyces cerevisiae ATCC 2601. Verificou-se, porém, diâmetros maiores nas zonas de inibição

4

Lateral flow strip assay  

DOEpatents

A lateral flow strip assay apparatus comprising a housing; a lateral flow strip in the housing, the lateral flow strip having a receiving portion; a sample collection unit; and a reagent reservoir. Saliva and/or buccal cells are collected from an individual using the sample collection unit. The sample collection unit is immersed in the reagent reservoir. The tip of the lateral flow strip is immersed in the reservoir and the reagent/sample mixture wicks up into the lateral flow strip to perform the assay.

Miles, Robin R. (Danville, CA) [Danville, CA; Benett, William J. (Livermore, CA) [Livermore, CA; Coleman, Matthew A. (Oakland, CA) [Oakland, CA; Pearson, Francesca S. (Livermore, CA) [Livermore, CA; Nasarabadi, Shanavaz L. (Livermore, CA) [Livermore, CA

2011-03-08

5

Hypochodriasis in Later Life  

Microsoft Academic Search

This study addressed two issues regarding hypochondriasis of later life: (1) whether this disorder is related more to psychopathology or health problems; and (2) the relationship of hypochondriasis to other later-life problems of anxiety, depression and paranoid reactions. Sixty later-life (>55) psychiatric inpatients were given a battery of psychological scales: MMPI-Pa (Harris-Lingoes subscales), State-Trait Anxiety Scale, Beck Depression Inventory (somatic

Immogene Gouvia; Lee Hyer; William R. Harrison; Janet Warsaw; Denise Coutsouridis

1986-01-01

6

Lateral superlattice solar cells.  

National Technical Information Service (NTIS)

A novel structure which comprises of a lateral superlattice as the active layer of a solar cell is proposed. If the alternating regions A and B of a lateral superlattice ABABAB. are chosen to have a Type-II band offset, it is shown that the performance of...

A. Mascarenhas Y. Zhang J. M. Millunchick R. D. Twesten E. D. Jones

1997-01-01

7

Amyotrophic lateral sclerosis  

MedlinePLUS

Lou Gehrig's disease; ALS; Upper and lower motor neuron disease; Motor neuron disease ... 74. Shaw PJ. Amyotrophic lateral sclerosis and other motor neuron diseases. In: Goldman L, Schafer AI, eds. Cecil Medicine . ...

8

Laterally bendable belt conveyor  

SciTech Connect

An endless, laterally flexible and bendable belt conveyor particularly adapted for coal mining applications in facilitating the transport of the extracted coal up- or downslope and around corners in a continuous manner is disclosed. The conveying means includes a flat rubber belt reinforced along the middle portion thereof along which the major portion of the belt tension is directed so as to cause rotation of the tubular shaped belt when trammed around lateral turns thus preventing excessive belt bulging distortion between adjacent belt supports which would inhibit belt transport. Pretension induced into the fabric reinforced flat rubber belt by conventional belt take-up means supports the load conveyed when the belt conveyor is making lateral turns. The carrying and return portions of the belt are supported and formed into a tubular shape by a plurality of shapers positioned along its length. Each shaper is supported from above by a monorail and includes clusters of idler rollers which support the belt. Additional cluster rollers in each shaper permit the belt supporting roller clusters to rotate in response to the belt's operating tension imposed upon the cluster rollers by induced lateral belt friction forces. The freely rotating roller clusters thus permit the belt to twist on lateral curves without damage to itself while precluding escape of the conveyed material by effectively enclosing it in the tube-shaped, inner belt transport length.

Peterson, W.J.

1982-09-24

9

Laterality of Amblyopia  

PubMed Central

Purpose To determine the frequency of right versus left eyes with unilateral amblyopia among children <18 years of age Design Analysis of data collected in randomized clinical trials conducted by the Pediatric Eye Disease Investigator Group. Methods The laterality of the amblyopic eye was analyzed in 2,635 subjects <18 years of age who participated in 9 multicenter prospective randomized treatment trials. Eligibility criteria for these clinical trials included unilateral amblyopia associated with strabismus, anisometropia or both, with visual acuity between 20/40 and 20/400. Logistic regression was used to assess the association of baseline and demographic factors with the laterality of amblyopia. Results Among subjects with anisometropic amblyopia (with or without strabismus), amblyopia was present more often in left than right eyes, with a relative prevalence of 59% in left eyes (95% confidence interval 57% to 62%, p<0.001 from a test of proportion = 50%). However, among subjects with strabismic only amblyopia there was no laterality predilection (relative prevalence of 50% in left eyes, 95% confidence interval 47% to 54%, P=0.94). Conclusion Anisometropic amblyopia, with or without strabismus, occurs more often in left eyes than right eyes. This finding of amblyopia laterality may be related to microtropia, sighting dominance or other forms of ocular dominance, developmental or neurological factors, and/or laterality in the development of refractive error.

Repka, Michael; Simons, Kurt; Kraker, Raymond

2010-01-01

10

Laterally bendable belt conveyor  

DOEpatents

An endless, laterally flexible and bendable belt conveyor particularly adapted for coal mining applications in facilitating the transport of the extracted coal up- or downslope and around corners in a continuous manner is disclosed. The conveying means includes a flat rubber belt reinforced along the middle portion thereof along which the major portion of the belt tension is directed so as to cause rotation of the tubular shaped belt when trammed around lateral turns thus preventing excessive belt bulging distortion between adjacent belt supports which would inhibit belt transport. Pretension induced into the fabric reinforced flat rubber belt by conventional belt take-up means supports the load conveyed when the belt conveyor is making lateral turns. The carrying and return portions of the belt are supported and formed into a tubular shape by a plurality of shapers positioned along its length. Each shaper is supported from above by a monorail and includes clusters of idler rollers which support the belt. Additional cluster rollers in each shaper permit the belt supporting roller clusters to rotate in response to the belt's operating tension imposed upon the cluster rollers by induced lateral belt friction forces. The freely rotating roller clusters thus permit the belt to twist on lateral curves without damage to itself while precluding escape of the conveyed material by effectively enclosing it in the tube-shaped, inner belt transport length.

Peterson, William J. (Coraopolis, PA)

1985-01-01

11

Amyotrophic lateral sclerosis  

PubMed Central

OBJECTIVE To discuss the epidemiology, pathogenesis, diagnosis, expected course, prognosis, and treatment of amyotrophic lateral sclerosis (ALS), a degenerative disorder of the nervous system associated with progressive weakness. QUALITY OF EVIDENCE PubMed and the Cochrane Database of Systematic Reviews were searched using the MeSH headings “amyotrophic lateral sclerosis,” “therapy,” “epidemiology,” and “etiology.” Articles containing the best available evidence were reviewed. Most provided level II and III evidence. There were some level I drug trials. MAIN MESSAGE Amyotrophic lateral sclerosis is associated with progressive dysarthria, dysphagia, and weakness in the extremities. Diagnosis is based on physical examination, electrophysiology, and excluding other confounding conditions. There is no cure for this devastating disorder. Certain treatments, however, can improve survival and quality of life. CONCLUSION Because ALS is a complex disease, care of ALS patients is best provided at multidisciplinary clinics that specialize in managing patients with this disorder.

Shoesmith, Christen L.; Strong, Michael J.

2006-01-01

12

Laterally bendable belt conveyor  

SciTech Connect

An endless, laterally flexible and bendable belt conveyor particularly adapted for coal mining applications in facilitating the transport of the extracted coal up- or downslope and around corners in a continuous manner is disclosed. The conveying means includes a flat rubber belt reinforced along the middle portion thereof along which the major portion of the belt tension is directed so as to cause rotation of the tubular shaped belt when trammed around lateral turns thus preventing excessive belt bulging distortion between adjacent belt supports which would inhibit belt transport. Pretension induced into the fabric reinforced flat rubber belt by conventional belt take-up means supports the load conveyed when the belt conveyor is making laterial turns. The carrying and return portions of the belt are supported and formed into a tubular shape by a plurality of shapers positioned along its length. Each shaper is supported from above by a monorail and includes clusters of idler rolles which support the belt. Additional cluster rollers in each shaper permit the belt supporting roller clusters to rotate in response to the belt's operating tension imposed upon the cluster rollers by induced lateral belt friction forces. The freely rotating roller clusters thus permit the belt to twist on lateral curves without damage to itself while precluding escape of the conveyed material by effectively enclosing it in the tube-shaped, inner belt transport length.

Peterson, W.J.

1985-07-02

13

Amyotrophic Lateral Sclerosis Association  

Microsoft Academic Search

Amyotrophic lateral sclerosis (ALS), most commonly known as Lou Gehrig's disease, is a progressive neurodegenerative disease that attacks nerve cells in the brain and spinal cord resulting in muscle weakness and atrophy. The ALS Association's national Web site provides comprehensive information on a wide variety of topics pertinent to ALS patients, caregivers, family members, and health care professionals. This well-organized,

Julie M. Smith

2008-01-01

14

Lateral interactions in amblyopia  

Microsoft Academic Search

We studied lateral neural interactions in strabismic (n=6) and anisometropic amblyopes (n=3) by measuring reductions in the perceived contrast of a foveally viewed Gabor centred in a horizontal array of closely neighboring Gabors. Strabismic amblyopes, but not anisometropic amblyopes, failed to show the reduction in perceived contrast typical of normal vision [J. Opt. Soc. Amer. A 15 (1998) 1733] when

Dave Ellemberg; Robert F. Hess; A. Serge Arsenault

2002-01-01

15

Lateral interactions in amblyopia  

Microsoft Academic Search

We studied lateral neural interactions in strabismic (n ¼ 6) and anisometropic amblyopes (n ¼ 3) by measuring reductions in the perceived contrast of a foveally viewed Gabor centred in a horizontal array of closely neighboring Gabors. Strabismic amblyopes, but not anisometropic amblyopes, failed to show the reduction in perceived contrast typical of normal vision (J. Opt. Soc. Amer. A

Dave Ellemberg; Robert F. Hess; A. Serge

2002-01-01

16

Delete It Later  

NSDL National Science Digital Library

Have you ever wanted to delete a Facebook or Twitter post after it was published? It can be a good practice but can be tough to remember. Delete It Later allows users to schedule the posting of statuses, updates, and photos along with the option to schedule when the content will be removed. This version is compatible with all operating systems.

2014-05-22

17

Isolated lateral rectus myositis.  

PubMed

Orbital myositis is a rare non-granulomatous inflammatory process within the orbit. Grave's disease and lymphoproliferative disorders are considered the most common cause of orbital myositis. The idiopathic form should be considered after exclusion of known causes or associations. Isolated orbital myositis is a very rare form of this disease. We report a case of an isolated lateral rectus myositis to draw the attention of physicians to this condition, as prompt treatment in our patient resulted in complete recovery. PMID:21063661

Obeid, Tahir H; Qanash, Sultan A; Abulaban, Ahmad A; Al-Shamy, Abdalrhman M

2010-11-01

18

Laterally oscillating nitinol engine  

Microsoft Academic Search

This patent describes a laterally oscillating nitinol engine comprising: a first L-shaped drive member journalled for pivoting horizontal oscillation about the juncture of the legs of the L-shaped member, a second drive member journalled for pivoting about a point proximate the outboard end of the shorter leg of the L-shaped member at a distance from the pivot journal of the

1987-01-01

19

Lateral internal sphincterotomy  

Microsoft Academic Search

Summary  Lateral internal sphincterotomy proved to be effective in 99 per cent of the 418 procedures in which it was performed. The\\u000a complication rate of 5 per cent was an improvement over most of the rates reported in the medical literature and over our\\u000a previous experience with posterior sphincterotomy and anoplasty. Anal wounds and fissures healed faster than with previous\\u000a procedures.

Ralph V. Bailey; Robert J. Rubin; Eugene P. Salvati

1978-01-01

20

Lateral conduction infrared photodetector  

DOEpatents

A photodetector for detecting infrared light in a wavelength range of 3-25 .mu.m is disclosed. The photodetector has a mesa structure formed from semiconductor layers which include a type-II superlattice formed of alternating layers of InAs and In.sub.xGa.sub.1-xSb with 0.ltoreq.x.ltoreq.0.5. Impurity doped regions are formed on sidewalls of the mesa structure to provide for a lateral conduction of photo-generated carriers which can provide an increased carrier mobility and a reduced surface recombination. An optional bias electrode can be used in the photodetector to control and vary a cut-off wavelength or a depletion width therein. The photodetector can be formed as a single-color or multi-color device, and can also be used to form a focal plane array which is compatible with conventional read-out integrated circuits.

Kim, Jin K. (Albuquerque, NM); Carroll, Malcolm S. (Albuquerque, NM)

2011-09-20

21

Reflexive Planning for Later Life  

ERIC Educational Resources Information Center

Informed by Giddens' (1991) concept of "reflexive life" planning and the notion of later life as a time of increasing social and financial risk, this research explores the idea of "reflexive planning for later life". We utilize a conceptual model that incorporates three types of planning for later life: public protection, self-insurance, and…

Denton, Margaret A.; Kemp, Candace L.; French, Susan; Gafni, Amiram; Joshi, Anju; Rosenthal, Carolyn J.; Davies, Sharon

2004-01-01

22

Laterally oscillating nitinol engine  

SciTech Connect

This patent describes a laterally oscillating nitinol engine comprising: a first L-shaped drive member journalled for pivoting horizontal oscillation about the juncture of the legs of the L-shaped member, a second drive member journalled for pivoting about a point proximate the outboard end of the shorter leg of the L-shaped member at a distance from the pivot journal of the L-shaped member, a bearing block secured to the end of longer leg of the L-shaped and having a guide hole. The second member extending through the guide hole and arranged to reciprocate therein, a shape memory alloy power element disposed in flexure secured at its ends to the bearing block and to the second member intermediate the sliding connection with the bearing block and the pivotal connection of the second member, means for disposing different temperature baths below the element whereby as the drive members oscillate about their journals the element alternately dips into one bath and then the other, and means for absorbing a portion of the energy developed by the engine and moving the power element from the cold bath to the hot bath.

Banks, R.

1987-09-08

23

Lateral coupled cavity semiconductor laser  

Microsoft Academic Search

This patent describes a monolithic lateral-coupled laser array comprised of at least two stripe laser cavities of different effective length in close parallel proximity to each other for coupling of radiation. The longer of the stripe laser cavities is cleaved to provide separate parts, and the parts are cleaved coupled to form one strip laser cavity lateral coupled to the

J. Salzman; R. J. Lang; A. Yariv

1987-01-01

24

Lateral Thinking and Technology Education  

Microsoft Academic Search

The emergence of lateral thinking in recent years is a natural reaction to the enormous increase of information a human being is “bombarded” with, in the post industrial revolution era. Vertical thinking, with its sequential and fixed-order rules, which has been the foundation of traditional education, is increasingly being complemented by lateral thinking which aims at freeing the mind from

Shlomo Waks

1997-01-01

25

Cerebral lateralization and spatial ability  

Microsoft Academic Search

Frequencies of three cerebral dominance genotypes who show right or left ear superiority on a verbal dichotic listening test and left or right field superiority on a tachistoscopic lateral field test of perceptual dominance are deduced. A hypothesis is offered relating direction of cerebral dominance, as defined by genotype, to degree of lateral specialization and perceptual ability, and a theoretical

Jerre Levy

1976-01-01

26

CT navigated lateral interbody fusion.  

PubMed

Lateral interbody fusion techniques are heavily reliant on fluoroscopy for retractor docking and graft placement, which expose both the patient and surgeon to high doses of radiation. Use of image-guided technologies with CT-based images, however, can eliminate this radiation exposure for the surgeon. We describe the surgical technique of performing lateral lumbar interbody fusion using CT navigation. PMID:23931938

Drazin, Doniel; Liu, John C; Acosta, Frank L

2013-10-01

27

Incontinence after lateral internal sphincterotomy  

Microsoft Academic Search

PURPOSE: This study was designed to evaluate the anatomic and functional consequences of lateral internal sphincterotomy in patients who developed anal incontinence and in matched controls. METHODS: The study includes 13 patients with anal incontinence after lateral internal sphincterotomy and 13 controls who underwent the same operation and were continent and satisfied with the results of the procedure. Patients underwent

Julio García-Aguilar; Carlos Belmonte Montes; Jose Javier Perez; Linda Jensen; Robert D. Madoff; W. Douglas Wong

1998-01-01

28

2006 Existing Conditions Plan, Channing Way to Durant Avenue ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2006 Existing Conditions Plan, Channing Way to Durant Avenue - Piedmont Way & the Berkeley Property Tract, East of College Avenue between Dwight Way & U.C. Memorial Stadium, Berkeley, Alameda County, CA

29

2006 Existing Conditions Plan, Durant Avenue to Bancroft Way ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2006 Existing Conditions Plan, Durant Avenue to Bancroft Way - Piedmont Way & the Berkeley Property Tract, East of College Avenue between Dwight Way & U.C. Memorial Stadium, Berkeley, Alameda County, CA

30

Lateral epicondylitis of the elbow.  

PubMed

Lateral epicondylitis, or "tennis elbow," is a common musculotendinous degenerative disorder of the extensor origin at the lateral humeral epicondyle. Repetitive occupational or athletic activities involving wrist extension and supination are thought to be causative. The typical symptoms include lateral elbow pain, pain with wrist extension, and weakened grip strength. The diagnosis is made clinically through history and physical examination; however, a thorough understanding of the differential diagnosis is imperative to prevent unnecessary testing and therapies. Most patients improve with nonoperative measures, such as activity modification, physical therapy, and injections. A small percentage of patients will require surgical release of the extensor carpi radialis brevis tendon. Common methods of release may be performed via percutaneous, arthroscopic, or open approaches. PMID:23398951

Tosti, Rick; Jennings, John; Sewards, J Milo

2013-04-01

31

Lateral coupled cavity semiconductor laser  

SciTech Connect

This patent describes a monolithic lateral-coupled laser array comprised of at least two stripe laser cavities of different effective length in close parallel proximity to each other for coupling of radiation. The longer of the stripe laser cavities is cleaved to provide separate parts, and the parts are cleaved coupled to form one strip laser cavity lateral coupled to the shorter laser cavity. A separate stripe contact varies the relative currents supplied to each laser cavity, including the cleaved coupled cavities of the longer of the stripe laser cavities.

Salzman, J.; Lang, R.J.; Yariv, A.

1987-06-16

32

Borehole optical lateral displacement sensor  

DOEpatents

There is provided by this invention an optical displacement sensor that utilizes a reflective target connected to a surface to be monitored to reflect light from a light source such that the reflected light is received by a photoelectric transducer. The electric signal from the photoelectric transducer is then imputed into electronic circuitry to generate an electronic image of the target. The target`s image is monitored to determine the quantity and direction of any lateral displacement in the target`s image which represents lateral displacement in the surface being monitored. 4 figs.

Lewis, R.E.

1998-10-20

33

Immunochromatographic lateral flow strip tests.  

PubMed

The immunochromatographic lateral flow strip test is a one-step test that facilitates low-cost, rapid identification of various analytes at the point of care. We have developed lateral flow strip tests for the specific qualitative or semiquantitative detection of antigens, antibodies, and haptens, such as drug residues. Here, we describe in detail the preparation of three examples of the strip tests for detection of (a) the infectious bursal disease virus; (b) Trichinella specific antibodies, and (c) Clenbuterol residues in urine samples. PMID:19159098

Zhang, Gaiping; Guo, Junqing; Wang, Xuannian

2009-01-01

34

Genetics Home Reference: Juvenile primary lateral sclerosis  

MedlinePLUS

... Recent literature OMIM Genetic disorder catalog Conditions > Juvenile primary lateral sclerosis On this page: Description Genetic changes ... Glossary definitions Reviewed July 2013 What is juvenile primary lateral sclerosis? Juvenile primary lateral sclerosis is a ...

35

Biomarkers for Amyotrophic Lateral Sclerosis.  

National Technical Information Service (NTIS)

The invention provides a method for diagnosing amyotrophic lateral sclerosis (ALS) in a subject, a method for assessing the effectiveness of a drug in treating ALS, and a method for determining the site of onset of ALS in a subject. Each method comprises ...

R. P. Bowser S. Ranganathan

2004-01-01

36

Lateral buckling of monorail beams  

Microsoft Academic Search

The resistances of steel I-section monorail beams to lateral buckling are difficult to assess because monorails are often not well restrained against twisting. Monorails are supported at intervals along the top flange, but are free along the bottom flange, except at supported ends where vertical stiffeners may restrain the bottom flange. The buckling resistance is increased by the loading which

N. S. Trahair

2008-01-01

37

Functional Lateralization of the Brain.  

ERIC Educational Resources Information Center

Research concerning lateralization of human brain functions is examined in light of the recent publication of the Kaufman Assessment Battery for Children. Following a review of research methodologies and functions ascribed to the hemispheres of the brain, differences are portrayed as complementary and coexisting modes of cognitive processing.…

Dean, Raymond S.

1984-01-01

38

Lateral Violence: Nurse Against Nurse  

Microsoft Academic Search

Violence between and among workers is not unusual today. In health care, violence is a growing problem among nurses, as well as other disciplines. This independent study module focuses on lateral violence between and among nurses. The purpose of this independent study module is to increase nurses' awareness and understanding of the problem of violence between nurse co-workers in the

Patricia A. Rowell

39

Lateral diffusion in fluid systems  

SciTech Connect

It is shown that an extension of the free-volume model introduced by Cohen and Turnbull (see Refs. 6-8), can serve as a starting point in the development of a microscopic theory of lateral diffusion in membranes and monolayers. (AIP)

MacCarthy, J.E.; Kozak, J.J.

1982-08-15

40

Laterality of basic auditory perception  

Microsoft Academic Search

Laterality (left–right ear differences) of auditory processing was assessed using basic auditory skills: (1) gap detection, (2) frequency discrimination, and (3) intensity discrimination. Stimuli included tones (500, 1000, and 4000 Hz) and wide-band noise presented monaurally to each ear of typical adult listeners. The hypothesis tested was that processing of tonal stimuli would be enhanced by left ear (LE) stimulation

Yvonne S. Sininger; Anjali Bhatara

2011-01-01

41

Laterality of basic auditory perception  

Microsoft Academic Search

Laterality (left–right ear differences) of auditory processing was assessed using basic auditory skills: (1) gap detection, (2) frequency discrimination, and (3) intensity discrimination. Stimuli included tones (500, 1000, and 4000 Hz) and wide-band noise presented monaurally to each ear of typical adult listeners. The hypothesis tested was that processing of tonal stimuli would be enhanced by left ear (LE) stimulation

Yvonne S. Sininger; Anjali Bhatara

2012-01-01

42

Laterality of Basic Auditory Perception  

PubMed Central

Laterality (left-right ear differences) of auditory processing was assessed using basic auditory skills: 1) gap detection 2) frequency discrimination and 3) intensity discrimination. Stimuli included tones (500, 1000 and 4000 Hz) and wide-band noise presented monaurally to each ear of typical adult listeners. The hypothesis tested was: processing of tonal stimuli would be enhanced by left ear (LE) stimulation and noise by right ear (RE) presentations. To investigate the limits of laterality by 1) spectral width, a narrow band noise (NBN) of 450 Hz bandwidth was evaluated using intensity discrimination and 2) stimulus duration, 200, 500 and 1000 ms duration tones were evaluated using frequency discrimination. Results A left ear advantage (LEA) was demonstrated with tonal stimuli in all experiments but an expected REA for noise stimuli was not found. The NBN stimulus demonstrated no LEA and was characterized as a noise. No change in laterality was found with changes in stimulus durations. The LEA for tonal stimuli is felt to be due to more direct connections between the left ear and the right auditory cortex which has been shown to be primary for spectral analysis and tonal processing. The lack of a REA for noise stimuli is unexplained. Sex differences in laterality for noise stimuli were noted but were not statistically significant. This study did establish a subtle but clear pattern of LEA for processing of tonal stimuli.

Sininger, Yvonne S.; Bhatara, Anjali

2010-01-01

43

Diagnosing and treating lateral epicondylitis.  

PubMed Central

Lateral epicondylitis is often encountered in primary care. Although its diagnosis can be fairly straightforward, its treatment is often difficult. This review examines the epidemiology, pathophysiology, and clinical presentation of tennis elbow. Management options are discussed. Images Figure 1 Figure 2 Figure 3 Figure 4

Geoffroy, P.; Yaffe, M. J.; Rohan, I.

1994-01-01

44

Neuroimaging in Amyotrophic Lateral Sclerosis  

Microsoft Academic Search

Summary  Amyotrophic lateral sclerosis (ALS) is a motor neuron disease characterized by progressive degeneration of upper motor neurons\\u000a (UMN) and lower motor neurons (LMN). While LMN dysfunction can be confirmed by electromyography (EMG) and muscle biopsy, UMN\\u000a involvement is more difficult to detect, particularly in the early phase. Objective and sensitive measures of UMN dysfunction\\u000a are needed for early diagnosis and

Sumei Wang; Elias R. Melhem; Harish Poptani; John H. Woo

2011-01-01

45

Management of amyotrophic lateral sclerosis.  

PubMed

Motor Neuron Diseases (MNDs) are neurological disorders characterized by the selective and progressive degeneration of motor neurons. Amyotrophic Lateral Sclerosis (ALS), commonly known as Lou Gehrig's disease, is the most common. ALS causes diffuse muscle weakness and death secondary to respiratory failure. The diagnosis is made clinically, supported by electrodiagnostic testing. Although medications are limited, careful attention to breathing, nutrition, and patient mobility can have a major, positive impact on the course of the disease. PMID:24279194

Bali, Taha; Miller, Timothy M

2013-01-01

46

Lateral dampers for thrust bearings  

NASA Technical Reports Server (NTRS)

The development of lateral damping schemes for thrust bearings was examined, ranking their applicability to various engine classes, selecting the best concept for each engine class and performing an in-depth evaluation. Five major engine classes were considered: large transport, military, small general aviation, turboshaft, and non-manrated. Damper concepts developed for evaluation were: curved beam, constrained and unconstrained elastomer, hybrid boost bearing, hydraulic thrust piston, conical squeeze film, and rolling element thrust face.

Hibner, D. H.; Szafir, D. R.

1985-01-01

47

School Readiness and Later Achievement  

Microsoft Academic Search

Using 6 longitudinal data sets, the authors estimate links between three key elements of school readiness—school-entry academic, attention, and socioemotional skills—and later school reading and math achievement. In an effort to isolate the effects of these school-entry skills, the authors ensured that most of their regression models control for cognitive, attention, and socioemotional skills measured prior to school entry, as

Greg J. Duncan; Chantelle J. Dowsett; Amy Claessens; Katherine Magnuson; Aletha C. Huston; Pamela Klebanov; Linda S. Pagani; Leon Feinstein; Mimi Engel; Jeanne Brooks-Gunn; Holly Sexton; Kathryn Duckworth; Crista Japel

2007-01-01

48

VIEW OF PIEDMONT AVENUE BETWEEN CHANNING WAY AND DURANT AVENUE. ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

VIEW OF PIEDMONT AVENUE BETWEEN CHANNING WAY AND DURANT AVENUE. 2325 PIEDMONT (MRS. F.W. FISH HOUSE DESIGNED BY CHARLES S. KAISER, 1910. SEEN FROM WEST SIDE OF PIEDMONT LOOKING NORTH. Photograph by Fredrica Drotos and Michael Kelly, July 9, 2006 - Piedmont Way & the Berkeley Property Tract, East of College Avenue between Dwight Way & U.C. Memorial Stadium, Berkeley, Alameda County, CA

49

VIEW OF PIEDMONT AVENUE AT INTERSECTION OF DURANT AVENUE WITH ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

VIEW OF PIEDMONT AVENUE AT INTERSECTION OF DURANT AVENUE WITH DOME OF THE INTERNATIONAL HOUSE AT 2299 PIEDMONT AVENUE. BY GEORGE W. KELHAM, 1929, SEEN FROM SW CORNER LOOKING NORTH. Photograph by Fredrica Drotos and Michael Kelly, July 9, 2006 - Piedmont Way & the Berkeley Property Tract, East of College Avenue between Dwight Way & U.C. Memorial Stadium, Berkeley, Alameda County, CA

50

Vision assisted aircraft lateral navigation  

NASA Astrophysics Data System (ADS)

Surface operation is currently one of the least technologically equipped phases of aircraft operation. The increased air traffic congestion necessitates more aircraft operations in degraded weather and at night. The traditional surface procedures worked well in most cases as airport surfaces have not been congested and airport layouts were less complex. Despite the best efforts of FAA and other safety agencies, runway incursions continue to occur frequently due to incorrect surface operation. Several studies conducted by FAA suggest that pilot induced error contributes significantly to runway incursions. Further, the report attributes pilot's lack of situational awareness - local (e.g., minimizing lateral deviation), global (e.g., traffic in the vicinity) and route (e.g., distance to next turn) - to the problem. An Enhanced Vision System (EVS) is one concept that is being considered to resolve these issues. These systems use on-board sensors to provide situational awareness under poor visibility conditions. In this paper, we propose the use of an Image processing based system to estimate the aircraft position and orientation relative to taxiway markings to use as lateral guidance aid. We estimate aircraft yaw angle and lateral offset from slope of the taxiway centerline and horizontal position of vanishing line. Unlike automotive applications, several cues such as aircraft maneuvers along assigned route with minimal deviations, clear ground markings, even taxiway surface, limited aircraft speed are available and enable us to implement significant algorithm optimizations. We present experimental results to show high precision navigation accuracy with sensitivity analysis with respect to camera mount, optics, and image processing error.

Mohideen, Mohamed Ibrahim; Ramegowda, Dinesh; Seiler, Peter

2013-05-01

51

Imaging lesions of the lateral hip.  

PubMed

The lateral aspect of the hip is composed of a complex array of osseous and soft tissue structures. Both common and uncommon clinical entities are encountered in the lateral hip. This article briefly introduces fundamental imaging anatomy and the functional roles of different osseous and soft tissue structures in the lateral aspect of the hip, followed by a discussion of relevant imaging findings of lateral hip pathology. Greater trochanteric pain syndrome is frequently encountered in patients with lateral hip pain and encompasses a spectrum of soft tissue abnormalities including trochanteric and subgluteal bursitis, and tendinopathy or tears of the gluteal tendons. In addition, different types of injuries to the gluteal myotendinous unit and injuries to the indirect head of the rectus femoris, proximal iliotibial band, and the lateral joint capsular ligaments can present with lateral hip pain. Some of the less common soft tissue abnormalities of the lateral hip include Morel-Lavallée lesion and meralgia paresthetica. PMID:23787984

Pan, Judong; Bredella, Miriam A

2013-07-01

52

Managing Complications of Diabetes in Later Life  

MedlinePLUS

... Download PDF Managing Complications of Diabetes in Later Life Download Join our e-newsletter! Resources Managing Complications of Diabetes in Later Life Tools and Tips Printer-friendly PDF Click here ...

53

Hereditary occurrence of lateral cervical fistulas.  

PubMed

Three cases of hereditary lateral cervical fistulas are reported. The patients had lateral cervical fistulas bilaterally and different types of auricular malformations. The mothers of the patients also had lateral cervical fistulas. Moreover, one mother had bilateral microtias and the other mothers bilateral preauricular fistulas. The literature is reviewed and discussed. PMID:3377420

Takato, T; Fukuda, O

1988-05-01

54

Lateral violence in the perioperative setting.  

PubMed

Lateral violence is disruptive, bullying, intimidating, or unsettling behavior that occurs between nurses in the workplace. The perioperative setting fosters lateral violence because of the inherent stress of performing surgery; high patient acuity; a shortage of experienced personnel; work demands; and the restriction and isolation of the OR, which allows negative behaviors to be concealed more easily. Lateral violence affects nurses' health and well-being and their ability to care for patients. Interventions to reduce lateral violence include empowerment of staff members and zero tolerance for lateral violence. PMID:19434948

Bigony, Lorraine; Lipke, Tammy G; Lundberg, Ashley; McGraw, Carrie A; Pagac, Gretchen L; Rogers, Anne

2009-04-01

55

[Genetics of amyotrophic lateral sclerosis].  

PubMed

Although the pathophysiology of amyotrophic lateral sclerosis remains currently unknown, involvement of genetic factors is worldwide accepted as a key clue in the motor neuron death. Since 1993 and the discovery of mutation in the SOD1 gene, number of genes linked to or promoting ALS had always growing. Among them, only four (SOD1, TARDBP, FUS and C9ORF72 genes) are unanimously recognized as convincing causative genetic factors for more than 60% of familial and probably 10% of sporadic ALS cases. Geographic origin of the studied populations tends to become one of the major items in the gene-ALS relationship: this was extremely stressed for C9ORF72. Concerning susceptibility genes factors, an increase of the risk of ALS is clearly shown for SMN1 and ATXN2 genes and accepted for some VEGF haplotypes. Finally, some modulating effects might also exist as underline for the relationships between ApoE and ALS that differ between European and North American studies. In inherited ALS, The European Federation of Neurological Societies (EFNS) edited rules that gave a legal frame to situations for which research of mutations were justified. Progress in the field of genetic raises major questions concerning the relevance of genetic studies from asymptomatic relatives. This first implies that the mutation identified in the proband case is perfectly characterized as a pathogenic mutation. PMID:24703222

Corcia, Philippe; Blasco, Hélène; Camu, William

2014-05-01

56

Examining lateral violence in the nursing workforce.  

PubMed

The decision to examine the phenomenon of lateral violence within the nursing workforce of a Southeastern tertiary care medical center evolved from the strong response of attendees to a nursing presentation on lateral violence. This paper describes the development and testing of the Lateral Violence in Nursing Survey. This questionnaire, designed to measure perceived incidence and severity of lateral violence, was administered online to 663 nursing staff participants. Forty-six percent of the study participants reported lateral violence as a "very serious" or "somewhat serious" problem, and 65% reported frequently observing lateral violence behaviors among coworkers. Education and effective leadership were found to mediate oppressive and negative behaviors, whereas ineffective leadership was found to exacerbate lateral violence. PMID:17987480

Stanley, Karen M; Martin, Mary M; Nemeth, Lynne S; Michel, Yvonne; Welton, John M

2007-11-01

57

Evaluation of Lateral Movement of Piled Bridge Abutment Undergoing Lateral Soil Movement in Soft Ground  

Microsoft Academic Search

This paper describes the lateral movement of piled bridge abutments caused by backfills behind the abutments. To analyze the lateral movement of piled bridge abutments, a precise investigation was performed on the field monitoring data obtained from forty-three abutments where lateral movement has occurred. The investigation focuses not only on the lateral movement of the abutments, but also on the

Won-Pyo Hong; Kwang-Wu Lee

2009-01-01

58

Retroviruses and amyotrophic lateral sclerosis  

PubMed Central

Amyotrophic lateral sclerosis (ALS) is a progressive, invariably fatal neurologic disorder resulting from upper and lower motor neuron degeneration, which typically develops during the sixth or seventh decade of life, and is diagnosed based on standard clinical criteria. Its underlying cause remains undetermined. The disease may occur with increased frequency within certain families, often in association with specific genomic mutations, while some sporadic cases have been linked to environmental toxins or trauma. Another possibility, first proposed in the 1970s, is that retroviruses play a role in pathogenesis. In this paper, we review the published literature for evidence that ALS is associated either with infection by an exogenous retrovirus or with the expression of human endogenous retroviral (HERV) sequences in cells of the central nervous system. A small percentage of persons infected with the human immunodeficiency virus-1 (HIV-1) or human T cell leukemia virus-1 (HTLV-1) develop ALS-like syndromes. While HTLV-1 associated ALS-like syndrome has several features that may distinguish it from classical ALS, HIV-infected patients may develop neurological manifestations that resemble classical ALS although it occurs at a younger age and they may show a dramatic improvement following the initiation of antiretroviral therapy. However, most patients with probable or definite ALS show no evidence of HIV-1 or HTLV-1 infection. In contrast, recent reports have shown a stronger association with HERV, as analysis of serum samples, and postmortem brain tissue from a number of patients with a classical ALS has revealed significantly increased expression of HERV-K, compared to controls. These findings suggest that endogenous retroviral elements are involved in the pathophysiology of ALS, but there is no evidence that they are the primary cause of the syndrome.

Alfahad, Tariq; Nath, Avindra

2013-01-01

59

Retroviruses and amyotrophic lateral sclerosis.  

PubMed

Amyotrophic lateral sclerosis (ALS) is a progressive, invariably fatal neurologic disorder resulting from upper and lower motor neuron degeneration, which typically develops during the sixth or seventh decade of life, and is diagnosed based on standard clinical criteria. Its underlying cause remains undetermined. The disease may occur with increased frequency within certain families, often in association with specific genomic mutations, while some sporadic cases have been linked to environmental toxins or trauma. Another possibility, first proposed in the 1970s, is that retroviruses play a role in pathogenesis. In this paper, we review the published literature for evidence that ALS is associated either with infection by an exogenous retrovirus or with the expression of human endogenous retroviral (HERV) sequences in cells of the central nervous system. A small percentage of persons infected with the human immunodeficiency virus-1 (HIV-1) or human T cell leukemia virus-1 (HTLV-1) develop ALS-like syndromes. While HTLV-1 associated ALS-like syndrome has several features that may distinguish it from classical ALS, HIV-infected patients may develop neurological manifestations that resemble classical ALS although it occurs at a younger age and they may show a dramatic improvement following the initiation of antiretroviral therapy. However, most patients with probable or definite ALS show no evidence of HIV-1 or HTLV-1 infection. In contrast, recent reports have shown a stronger association with HERV, as analysis of serum samples, and postmortem brain tissue from a number of patients with a classical ALS has revealed significantly increased expression of HERV-K, compared to controls. These findings suggest that endogenous retroviral elements are involved in the pathophysiology of ALS, but there is no evidence that they are the primary cause of the syndrome. PMID:23707220

Alfahad, Tariq; Nath, Avindra

2013-08-01

60

Chondrolysis after partial lateral meniscectomy in athletes  

Microsoft Academic Search

Rapid chondrolysis after partial arthroscopic lateral meniscectomy has been seldom reported in literature. Considering the\\u000a relatively high number of partial lateral meniscectomy performed, we cannot understand why this complication is so rare. The\\u000a purpose of this paper is to report a series of athletes developing a chondrolysis associated with posterolateral corner laxity\\u000a after a partial lateral meniscectomy and attempt to

Pier Paolo Mariani; Raffaele Garofalo; Fabrizio Margheritini

2008-01-01

61

Reliability of subsea pipelines against lateral instability  

Microsoft Academic Search

An approach for the reliability assessment of subsea pipelines against on-bottom lateral instability is presented in this work. Combined stresses\\/lateral displacement acting on offshore pipelines due to combined hydrodynamic loads including wave\\/current effects are computed using a non-linear finite element model. The model takes into account the effect of pipe–soil interaction. The resulting combined pipe stresses\\/lateral displacement are used as

T. Elsayed; H. Leheta; A. Yehya

2010-01-01

62

Reliability of subsea pipelines against lateral instability  

Microsoft Academic Search

An approach for the reliability assessment of subsea pipelines against on-bottom lateral instability is presented in this work. Combined stresses\\/lateral displacement acting on offshore pipelines due to combined hydrodynamic loads including wave\\/current effects are computed using a non-linear finite element model. The model takes into account the effect of pipe–soil interaction. The resulting combined pipe stresses\\/lateral displacement are used as

T. Elsayed; H. Leheta; A. Yehya

2012-01-01

63

Human olfactory lateralization requires trigeminal activation.  

PubMed

Rats are able to lateralize odors. This ability involves specialized neurons in the orbitofrontal cortex which are able to process the left, right and bilateral presentation of stimuli. However, it is not clear whether this function is preserved in humans. Humans are in general not able to differentiate whether a selective olfactory stimulant has been applied to the left or right nostril; however exceptions have been reported. Following a screening of 152 individuals with an olfactory lateralization test, we identified 19 who could lateralize odors above chance level. 15 of these "lateralizers" underwent olfactory fMRI scanning in a block design and were compared to 15 controls matched for age and sex distribution. As a result, both groups showed comparable activation of olfactory eloquent brain areas. However, subjects with lateralization ability had a significantly enhanced activation of cerebral trigeminal processing areas (somatosensory cortex, intraparietal sulcus). In contrast to controls, lateralizers furthermore exhibited no suppression in the area of the trigeminal principal sensory nucleus. An exploratory study with an olfactory change detection paradigm furthermore showed that lateralizers oriented faster towards changes in the olfactory environment. Taken together, our study suggests that the trigeminal system is activated to a higher degree by the odorous stimuli in the group of "lateralizers". We conclude that humans are not able to lateralize odors based on the olfactory input alone, but vary in the degree to which the trigeminal system is recruited. PMID:24825502

Croy, Ilona; Schulz, Max; Blumrich, Anna; Hummel, Cornelia; Gerber, Johannes; Hummel, Thomas

2014-09-01

64

Artificial lateral line canal for hydrodynamic detection  

NASA Astrophysics Data System (ADS)

Fish use their lateral line system to detect minute water motions. The lateral line consists of superficial neuromasts and canal neuromasts. The response properties of canal neuromasts differ from those of superficial ones. Here, we report the design, fabrication, and characterization of an artificial lateral line canal system. The characterization was done under various fluid conditions, including dipolar excitation and turbulent flow. The experimental results with dipole excitation match well with a mathematical model. Canal sensors also demonstrate significantly better noise immunity compared with superficial ones. Canal-type artificial lateral lines may become important for underwater flow sensing.

Yang, Yingchen; Klein, Adrian; Bleckmann, Horst; Liu, Chang

2011-07-01

65

Simultaneous Medial and Lateral Patellofemoral Ligament Reconstruction for Combined Medial and Lateral Patellar Subluxation  

PubMed Central

Medial patellar subluxation (MPS) is a disabling, often iatrogenic patellar instability due to previous lateral release for patellar instability. Lateral release destabilizes the patella on the lateral side, worsening the initial lateral instability and causing MPS. MPS is poorly recognized and may range from subluxation to true dislocation. This report describes a technique developed in response to episodes of medial and lateral patellar subluxation after failed lateral release for patellar instability. The technique uses a graft that extends from the medial patellofemoral ligament origin through the quadriceps tendon to the lateral epicondyle, thereby reconstructing both the medial and lateral patellofemoral ligaments, as well as providing simultaneous stability to both the medial and lateral sides of the patella.

Saper, Michael G.; Shneider, David A.

2014-01-01

66

Connections of the rat lateral septal complex.  

PubMed

The organization of lateral septal connections has been re-examined with respect to its newly defined subdivisions, using anterograde (PHAL) and retrograde (fluorogold) axonal tracer methods. The results confirm that progressively more ventral transverse bands in the hippocampus (defined by the orientation of the trisynaptic circuit) innervate progressively more ventral, transversely oriented sheets in the lateral septum. In addition, hippocampal field CA3 projects selectively to the caudal part of the lateral septal nucleus, which occupies topologically lateral regions of the transverse sheets, whereas field CA1 and the subiculum project selectively to the rostral and ventral parts of the lateral septal nucleus, which occupy topologically medial regions of the transverse sheets. Finally, the evidence suggests that progressively more ventral hippocampal bands innervate progressively thicker lateral septal sheets. In contrast, ascending inputs to the lateral septum appear to define at least 20 vertically oriented bands or subdivisions arranged orthogonal to the hippocampal input (Risold, P.Y. and Swanson, L.W., Chemoarchitecture of the rat lateral septal nucleus, Brain Res. Rev., 24 (1997) 91-113). Hypothalamic nuclei forming parts of behavior-specific subsystems share bidirectional connections with specific subdivisions of the lateral septal nucleus (especially the rostral part), suggesting that specific domains in the hippocampus may influence specific hypothalamic behavioral systems. In contrast, the caudal part of the lateral septal nucleus projects to the lateral hypothalamus and to the supramammillary nucleus, which projects back to the hippocampus and receives its major inputs from brainstem cell groups thought to regulate behavioral state. The neural system mediating defensive behavior shows these features rather clearly, and what is known about its organization is discussed in some detail. PMID:9385454

Risold, P Y; Swanson, L W

1997-09-19

67

Vehicle Lateral Control for Highway Automation  

Microsoft Academic Search

The objectives of lateral control for highway automation are to let vehicles track the center of a lane with small error and to maintain good ride quality under different vehicle speeds, loads, wind gust disturbances, and road conditions. In this paper, the lateral feedback and feedforward controllers are designed to satisfy these objectives by utilizing the frequency-shaped linear quadratic (FSLQ)

Huei Peng; Masayoshi Tomizuka

1990-01-01

68

Lateral buckling of overhanging crane trolley monorails  

Microsoft Academic Search

Lateral torsional buckling should be taken into account during the design of overhanging steel beams. One special type of overhanging beam is the crane trolley monorail. Lateral buckling of overhanging monorails under idealized loading and boundary conditions has been studied in the past using classical mathematical procedures. This paper aims to present a detailed investigation of overhanging monorails using finite

Kerem Murat Özdemir; Cem Topkaya

2006-01-01

69

The lateral triangle of the groin  

Microsoft Academic Search

Summary The lateral triangle (LT) of the groin is an area that includes the deep inguinal ring (DIR), and the tissues immediately lateral to it. It is vulnerable to develop recurrent indirect inguinal and interstitial hernias. An interstitial hernia is one in which the sac burrows through or between muscular layers. One typically presents as a palpable bulge at the

A. I. Gilbert; M. F. Graham; W. J. Voigt

2000-01-01

70

Later Life: A Time to Learn  

ERIC Educational Resources Information Center

In this article, an emerging framework for investigating and interpreting the experiences of learning in later life is presented. This framework is contextualized by a study in which the lived experiences of later-life computer learners were investigated. Significant ontological and existential interpretations from the study provided insights into…

Russell, Helen

2008-01-01

71

Lateral epicondylitis: review of injection therapies.  

PubMed

Lateral epicondylitis has several different treatment methods, with no single agreed upon therapy. This article summarizes the current literature on injection therapies for lateral epicondylitis. Glucocorticoid, botulinum toxin, autologous blood, platelet-rich plasma, hyaluronic acid, polidocanol, glycosaminoglycan, and prolotherapy injections are discussed. PMID:24095076

Judson, Christopher H; Wolf, Jennifer Moriatis

2013-10-01

72

Does lateral gas diffusion in leaves matter?  

Microsoft Academic Search

Photosynthesis depends on the diffusion of gaseous CO2 inside the leaf spaces from the stomatal entry point to the mesophyll cell walls. Although most research considers only the vertical diffusion from stomata on upper and\\/or leaf lower surfaces, some of the gas will diffuse in the lateral (paradermal) direction. The importance of lateral CO2 dif- fusion is reviewed, and the

JAMES I. L. MORISON; TRACY LAWSON

2007-01-01

73

Later Life Social Engagement and Health  

Microsoft Academic Search

The topic of later life social engagement is of growing importance worldwide given the confluence of large demographic, economic, and sociocultural trends. However, empirical research in this area faces some serious theoretical and methodological limitations. The purpose of this study was to address these limitations by: (1) examining the later life mental and physical health effects of five social roles,

Manacy Pai

2008-01-01

74

Arthroscopic Thermal Shrinkage for Hypermobile Lateral Meniscus  

Microsoft Academic Search

Background: The posterior segment of the lateral meniscus is relatively mobile as compared with that of the medial meniscus; that is because of its characteristic anatomy. Abnormal mobility of the lateral meniscus with no obvious rupture can be an unusual cause of knee pain and locking during deep knee flexion.Purpose: To evaluate results for a small series of patients with

Kenichi Ohtoshi; Masashi Kimura; Yasukazu Kobayashi; Hiroshi Higuchi; Shinichi Kikuchi

2004-01-01

75

Reappraisal of partial lateral internal sphincterotomy  

Microsoft Academic Search

PURPOSE: The aim of this study was to delineate the results, mortality, and morbidity of partial lateral internal sphincterotomy for the treatment of chronic anal fissure. METHOD: A retrospective review of 500 patients undergoing partial lateral internal sphincterotomy for chronic anal fissure between 1980 and 1990 was performed. Patients were identified by a review of an office surgical ledger and

B. J. Pernikoff; T. E. Eisenstat; R. J. Rubin; G. C. Oliver; E. P. Salvati

1994-01-01

76

Tailored lateral sphincterotomy for anal fissure  

Microsoft Academic Search

PURPOSE: Most surgical texts describe the length of division of the internal sphincter during closed lateral sphincterotomy as “to just above the dentate line,” resulting in significant rates of incontinence. This study reviews our experience using a “tailored” lateral sphincterotomy by selecting the height of sphincter to be divided with the aim of preserving more sphincter. METHODS: From 1976 to

David R. G. Littlejohn; Graham L. Newstead

1997-01-01

77

Arthroscopic Centralization of an Extruded Lateral Meniscus  

PubMed Central

Extrusion of the lateral meniscus has been reported after posterior root tear or radial tear, partial meniscectomy, and meniscoplasty of discoid meniscus. It has also been shown to be associated with the development of osteoarthritis. This technical note describes a new arthroscopic technique to centralize and stabilize the mid body of the lateral meniscus to restore and maintain the lateral meniscus function by repairing/preventing extrusion of the meniscus. A JuggerKnot Soft Anchor (Biomet, Warsaw, IN), loaded with a MaxBraid suture (Biomet), was placed on the lateral edge of the lateral tibial plateau, just anterior to the popliteal hiatus, through a midlateral portal. A Micro Suture Lasso Small Curve with Nitinol Wire Loop (Arthrex, Naples, FL) was used to pass 2 limbs of the MaxBraid suture through the meniscus at the margin between the meniscus and the capsule. Another anchor was inserted on the lateral edge of the lateral tibial plateau, 1 cm anterior to the first anchor, and the same procedure was repeated. The sutures were then tied by use of a self-locking sliding knot, achieving centralization and secure stabilization of the lateral meniscus.

Koga, Hideyuki; Muneta, Takeshi; Yagishita, Kazuyoshi; Watanabe, Toshifumi; Mochizuki, Tomoyuki; Horie, Masafumi; Nakamura, Tomomasa; Okawa, Atsushi; Sekiya, Ichiro

2012-01-01

78

Monitoring System Design for Lateral Vehicle Motion  

Microsoft Academic Search

Monitoring of lateral vehicle motion is very useful in many active safety applications such as yaw stability control and rollover prevention. Lateral velocity and sideslip angle are regarded as the most important motion variables. However, it is not feasible during vehicle operation to directly measure them due to the high cost of sensors, limitations to sensor technology, etc. Therefore, the

Sangoh Han; Kunsoo Huh

2011-01-01

79

Orbital Fracture: Significance of lateral wall  

PubMed Central

The lateral orbital wall is the strongest among other orbital walls. However, it is commonly fractured in the setting of severe facial trauma. The fracture usually occurs at the sphenozygomatic suture line. In general, patients with lateral wall fractures are commonly young male who may present with mid facial swelling and some degree of deformity. In some cases, lateral orbital wall fracture may be associated with visual loss or change in mental status due to associated intracranial injury. Imaging studies with computed tomography is important in the proper diagnosis and planning of the surgical intervention. Management of intracranial or eye injuries should be undertaken on emergent basis. Thereafter, significantly displaced lateral wall fractures need to be repaired on timely basis. Proper realignment of the plane of the lateral orbital wall at the sphenozygomatic suture along with the other complex articulations of the zygomatic bone is necessary for proper functional and aesthetic outcome.

Alsuhaibani, Adel H.

2010-01-01

80

Successful implementation of policies addressing lateral violence.  

PubMed

Lateral violence is a problem in nursing despite policies addressing the issue, which suggests that implementation of these policies may be ineffective. We used an evidence-based approach to locate and appraise evidence about effectively implementing lateral violence policies. Our search strategy emphasized preappraised evidence, and we found 12 sources that met our inclusion criteria. Most evidence was from low-level sources, which is not surprising due to the subjective and sensitive nature of this topic. The evidence did not indicate that there is consistent, effective implementation of lateral violence policies. The appraised evidence suggests the importance of collaboratively prepared implementation strategies. Administrator involvement and relationships with staff members and the presence of a commitment to positive behavior change before lateral violence incidents occur are factors that can lead to successful implementation of lateral violence policies. PMID:23265652

Coursey, Joy H; Rodriguez, Ricardo E; Dieckmann, Loraine S; Austin, Paul N

2013-01-01

81

Osteochondritis dissecans of the lateral femoral condyle following total resection of the discoid lateral meniscus  

Microsoft Academic Search

Purpose: The purpose of this study was to describe the clinical presentation of 6 athletically active children with symptomatic osteochondritis dissecans (OCD) of the lateral femoral condyle following total resection for a torn discoid lateral meniscus and to discuss its cause. Type of Study: Case series. Methods: Six patients in whom OCD affecting the lateral femoral condyle developed after total

Hiroshi Mizuta; Eiichi Nakamura; Yutaka Otsuka; Satoshi Kudo; Katsumasa Takagi

2001-01-01

82

Model to Design Drip Hose Lateral Line  

NASA Astrophysics Data System (ADS)

Introduction The design criterion for non-pressure compensating drip hose is normally to have 10% of flow variation (?q) in the lateral line, corresponding to 20% of head pressure variation (?H). Longer lateral lines in drip irrigation systems using conventional drippers provide cost reduction, but it is necessary to obtain to the uniformity of irrigation [1]. The use of ?q higher levels can provide longer lateral lines. [4] proposes the use of a 30% ?q and he found that this value resulted in distribution uniformity over 80%. [1] considered it is possible to extend the lateral line length using two emitters spacing in different section. He assumed that the spacing changing point would be at 40% of the total length, because this is approximately the location of the average flow according with [2]. [3] found that, for practical purposes, the average pressure is located at 40% of the length of the lateral line and that until this point it has already consumed 75% of total pressure head loss (hf ). In this case, the challenge for designers is getting longer lateral lines with high values of uniformity. Objective The objective of this study was to develop a model to design longer lateral lines using non-pressure compensating drip hose. Using the developed model, the hypotheses to be evaluated were: a) the use of two different spacing between emitters in the same lateral line allows longer length; b) it is possible to get longer lateral lines using high values of pressure variation in the lateral lines since the distribution uniformity stays below allowable limits. Methodology A computer program was developed in Delphi® based on the model developed and it is able to design lateral lines in level using non-pressure compensating drip hose. The input data are: desired distribution uniformity (DU); initial and final pressure in the lateral line; coefficients of relationship between emitter discharge and pressure head; hose internal diameter; pipe cross-sectional area with the dripper; and roughness coefficient for the Hazen-Williams equation. The program allows calculate the lateral line length with three possibilities: selecting two spacing between emitters and defining the exchange point; using two pre-established spacing between emitters and calculating the length of each section with different spacing; using one emitter spacing. Results Results showed that the use of two sections with different spacing between drippers in the lateral line didn't allow longer length but got better uniformity when compared with lateral line with one spacing between emitters. The adoption of two spacing increased the flow rate per meter in the final section which represented approximately 80% of the lateral line total length and this justifies their use. The software allowed DU above 90% with pressure head variation of 40% and the use of two spacing between emitters. Conclusions The developed model/software showed to be accurate, easy to handle and useful for lateral line design using non-pressure compensating drip hose. References [1] ANDRADE, L. A. D. Estudo de uniformidade de emissão de água utilizando diferentes espaçamentos entre gotejadores na linha lateral. 2009. 87 f. Tese (Doutorado em Agronomia/Irigação e Drenagem) - Faculdade de Ciências Agronômicas, Universidade Estadual Paulista 'Julio de Mesquita Filho', Botucatu, (2009). [2] KELLER, J.; BLIESNER, R. D. Sprinkle and trickle irrigation. Caldwell: Blackburn Press, (1990). 652 p. [3] TALENS, J. A. M. Riego localizado y fertirrigacion. Madrid: Mundi-Prensa, (2002). 533 p. [4] WU, I. P. An assessment of hydraulic design of micro-irrigation systems. Agricultural Water Management, Amsterdan, v. 32, n. 3

Ludwig, Rafael; Cury Saad, João Carlos

2014-05-01

83

Lateral femoral cutaneous neuralgia: an anatomical insight.  

PubMed

A detailed anatomic study was carried out on the lateral femoral cutaneous nerve to better understand the etiology and treatment of lateral femoral cutaneous neuralgia. As it passed from the pelvis into the thigh, the lateral femoral cutaneous nerve ran through an "aponeuroticofascial tunnel," beginning at the iliopubic tract and ending at the inguinal ligament; as it passed through the tunnel, an enlargement in its side-to-side diameter was observed, suggesting that the fascial structures proximal to the inguinal ligament may be implicated in the genesis of lateral femoral cutaneous neuralgia. The finding of pseudoneuromas at this location, distant from the inguinal ligament, supports this hypothesis. The anterior superior iliac spine is located approximately 0.7 cm from the lateral femoral cutaneous nerve and serves as the bony landmark for nerve localization. Within the first 3 cm of leaving the pelvis, the lateral femoral cutaneous nerve was observed deep to the fascia lata; therefore, surgical dissection within the subcutaneous fascia may be conducted with relative impunity near the anterior superior iliac spine just inferior to the inguinal ligament. In 36% of cases there was no posterior branch of the nerve, which is correlated to lateral femoral cutaneous neuralgia symptoms often being limited to the anterior branch region. An accessory nerve was found in 30% of cases. PMID:12794914

Dias Filho, L C; Valença, M M; Guimarães Filho, F A V; Medeiros, R C; Silva, R A M; Morais, M G V; Valente, F P; França, S M L

2003-07-01

84

Olfactory coding in the honeybee lateral horn.  

PubMed

Olfactory systems dynamically encode odor information in the nervous system. Insects constitute a well-established model for the study of the neural processes underlying olfactory perception. In insects, odors are detected by sensory neurons located in the antennae, whose axons project to a primary processing center, the antennal lobe. There, the olfactory message is reshaped and further conveyed to higher-order centers, the mushroom bodies and the lateral horn. Previous work has intensively analyzed the principles of olfactory processing in the antennal lobe and in the mushroom bodies. However, how the lateral horn participates in olfactory coding remains comparatively more enigmatic. We studied odor representation at the input to the lateral horn of the honeybee, a social insect that relies on both floral odors for foraging and pheromones for social communication. Using in vivo calcium imaging, we show consistent neural activity in the honeybee lateral horn upon stimulation with both floral volatiles and social pheromones. Recordings reveal odor-specific maps in this brain region as stimulations with the same odorant elicit more similar spatial activity patterns than stimulations with different odorants. Odor-similarity relationships are mostly conserved between antennal lobe and lateral horn, so that odor maps recorded in the lateral horn allow predicting bees' behavioral responses to floral odorants. In addition, a clear segregation of odorants based on pheromone type is found in both structures. The lateral horn thus contains an odor-specific map with distinct representations for the different bee pheromones, a prerequisite for eliciting specific behaviors. PMID:24560579

Roussel, Edith; Carcaud, Julie; Combe, Maud; Giurfa, Martin; Sandoz, Jean-Christophe

2014-03-01

85

[Slowly progressive dysarthria in primary lateral sclerosis].  

PubMed

Slowly progressive dysarthria over many years may be the only sign of primary lateral sclerosis (PLS). Clinically it presents as pseudobulbar palsy which can be differentiated from amyotrophic lateral sclerosis (ALS) by the longer disease duration (> or =4 years), central pathological magnetic-evoked potentials to the tongue and lack of denervation in EMG. In contrast, hereditary spastic paraplegia (HSP) is characterized by a primary spasticity of the lower limbs, mostly later onset, the fact that other family members are affected and in isolated cases by positive genetic testing for mutations. PMID:20532474

Urban, P P; Wellach, I; Pohlmann, C

2010-08-01

86

Rapid prototyping of lateral flow assays.  

PubMed

Principles and characteristics of lateral flow strip assays are reviewed. Recent technology developments permit the use of inexpensive electronic readers for interrogating lateral flow strip test results, thus avoiding the inevitable variation and subjectivity of visual inspection to assess the capture of reporter-labeled analyte on test lines of the strip. Protocols for developing lateral flow assays are described, including two specific case studies for assaying cotinine (a small-molecule metabolite of nicotine) in a competitive format, and assaying HIV antibodies in a sandwich-type assay format. PMID:19159100

Volkov, Alexander; Mauk, Michael; Corstjens, Paul; Niedbala, R Sam

2009-01-01

87

Individualized optimal surgical extent of the lateral neck in papillary thyroid cancer with lateral cervical metastasis.  

PubMed

Despite an excellent prognosis, cervical lymph node (LN) metastases are common in patients with papillary thyroid cancer (PTC). The presence of metastasis is associated with an increased risk of locoregional recurrence, which significantly impairs quality of life and may decrease survival. Therefore, it has been an important determinant of the extent of lateral LN dissection in the initial treatment of PTC patients with lateral cervical metastasis. However, the optimal extent of therapeutic lateral neck dissection (ND) remains controversial. Optimizing the surgical extent of LN dissection is fundamental for balancing the surgical morbidity and oncological benefits of ND in PTC patients with lateral neck metastasis. We reviewed the currently available literature regarding the optimal extent of lateral LN dissection in PTC patients with lateral neck metastasis. Even in cases with suspicion of metastatic LN at the single lateral level or isolated metastatic lateral LN, the application of ND including all sublevels from IIa and IIb to Va and Vb may be overtreatment, due to the surgical morbidity. When there is no suspicion of LN metastasis at levels II and V, or when multilevel aggressive neck metastasis is not found, sublevel IIb and Va dissection may not be necessary in PTC patients with lateral neck metastasis. Thus consideration of the individualized optimal surgical extent of lateral ND is important when treating PTC patients with lateral cervical metastasis. PMID:23857026

Park, Jae-Yong; Koo, Bon Seok

2014-06-01

88

Septum formation of the lateral ventricles.  

PubMed

In an MRI study examining anomalies of the septum pellucidum in 505 cases, we detected bilateral septum formation of the lateral ventricles in a 17-month-old baby. In this study, we evaluate 505 (242 males and 263 females) patients referred to the Emaray Imaging Center, Ankara, Turkey with various prediagnoses. We specially selected all the cases from a non-psychotic population. We obtained MRI scans on a 1-Tesla imager (Picker International, Highland Heights, Ohio, USA), with slices of 5 and 6 mm thickness. In axial and coronal sections, we observed septum formation laterally between the anterior horn and the ventricular body of the lateral ventricles. Radio opaque septum formations started from the caudate nucleus and stretched to the genu of the corpus callosum. There was a second septum formation between the posterior horn and the ventricular body of the right lateral ventricle. It started from the caudate nucleus and stretched to the cavum vergae. PMID:16127534

Celik, Hakam H; Aldur, Mustafa M; Tatar, Ilkan; Ozkul, Emine; Tascioglu, Ayse B

2005-08-01

89

Symplastic intercellular connectivity regulates lateral root patterning.  

PubMed

Cell-to-cell communication coordinates the behavior of individual cells to establish organ patterning and development. Although mobile signals are known to be important in lateral root development, the role of plasmodesmata (PD)-mediated transport in this process has not been investigated. Here, we show that changes in symplastic connectivity accompany and regulate lateral root organogenesis in Arabidopsis. This connectivity is dependent upon callose deposition around PD affecting molecular flux through the channel. Two plasmodesmal-localized ?-1,3 glucanases (PdBGs) were identified that regulate callose accumulation and the number and distribution of lateral roots. The fundamental role of PD-associated callose in this process was illustrated by the induction of similar phenotypes in lines with altered callose turnover. Our results show that regulation of callose and cell-to-cell connectivity is critical in determining the pattern of lateral root formation, which influences root architecture and optimal plant performance. PMID:23850190

Benitez-Alfonso, Yoselin; Faulkner, Christine; Pendle, Ali; Miyashima, Shunsuke; Helariutta, Ykä; Maule, Andrew

2013-07-29

90

Lateral Force Device for Underwater Towed Array.  

National Technical Information Service (NTIS)

A lateral force device for displacing a towed underwater acoustic cable providing displacement in the horizontal and vertical directions having a spool and a rotationally mounted winged fuselage. The hollow spool is mounted on a cable with cable elements ...

N. Owsley J. F. Law R. Vanasse S. Ebner R. Knutson

1993-01-01

91

Lateral Transpsoas Fusion: Indications and Outcomes  

PubMed Central

Spinal fusion historically has been used extensively, and, recently, the lateral transpsoas approach to the thoracic and lumbar spine has become an increasingly common method to achieve fusion. Recent literature on this approach has elucidated its advantage over more traditional anterior and posterior approaches, which include a smaller tissue dissection, potentially lower blood loss, no need for an access surgeon, and a shorter hospital stay. Indications for the procedure have now expanded to include degenerative disc disease, spinal stenosis, degenerative scoliosis, nonunion, trauma, infection, and low-grade spondylolisthesis. Lateral interbody fusion has a similar if not lower rate of complications compared to traditional anterior and posterior approaches to interbody fusion. However, lateral interbody fusion has unique complications that include transient neurologic symptoms, motor deficits, and neural injuries that range from 1 to 60% in the literature. Additional studies are required to further evaluate and monitor the short- and long-term safety, efficacy, outcomes, and complications of lateral transpsoas procedures.

Patel, Vishal C.; Park, Daniel K.; Herkowitz, Harry N.

2012-01-01

92

Lateral Inflow into High-Velocity Channels.  

National Technical Information Service (NTIS)

This Coastal and Hydraulics Engineering Technical Note (CHETN) investigates lateral flow discharging into a high-velocity channel. The results of a series of laboratory and numerical model experiments are presented. Various geometric and hydraulic conditi...

R. L. Stockstill

2007-01-01

93

Dynamic Lateral Earth Pressure on Underground Structures.  

National Technical Information Service (NTIS)

The dynamic lateral earth pressures resulting from underground detonation can cause severe damage to underground structures. The shock exerted on an underground structure caused by an underground explosion will vary with the detonation depth, the intensit...

S. M. Helwany A. Chowdhury

2000-01-01

94

Lateral Hip Pain in an Athletic Population  

PubMed Central

Context: Historically, the term greater trochanteric pain syndrome has been used to describe a spectrum of conditions that cause lateral-sided hip pain, including greater trochanteric bursitis, snapping iliotibial band, and/or strains or tendinopathy of the abductor mechanism. Diagnosis of these conditions may be difficult because clinical presentations are variable and sometimes inconclusive. Especially difficult is differentiating intrinsic pain from pain referred to the greater trochanteric region. The purposes of this article are to review the relevant anatomy and pathophysiology of the lateral hip. Evidence Acquisition: Data were collected through a thorough review of the literature conducted through a MEDLINE search of all relevant papers between 1980 and January 2010. Results: Recent advances in imaging and an improved understanding of pathomechanics have helped to guide the evaluation, diagnosis, and appropriate treatment for patients presenting with lateral hip pain. Conclusion: Various diagnostic tools and treatment modalities can be used to effectively manage the athletic patient presenting with lateral hip pain.

Grumet, Robert C.; Frank, Rachel M.; Slabaugh, Mark A.; Virkus, Walter W.; Bush-Joseph, Charles A.; Nho, Shane J.

2010-01-01

95

Lateral releases of the subscapularis tendon  

PubMed Central

The technique of arthroscopic subscapularis repair continues to evolve. A three-sided subscapularis release (e.g. anterior, posterior, superior) is commonly advocated for improving tendon excursion to bone. However, a lateral release is commonly required as well, particularly for full thickness, upper subscapularis tears and full thickness, complete subscapularis tears. We describe the techniques to identify and release the lateral subscapularis border, which aids in the completion of other releases.

Lo, Ian K.Y.; Nelson, Atiba A.; Burkhart, Stephen S

2013-01-01

96

Lateral displacement estimation using tissue incompressibility  

Microsoft Academic Search

Using the incompressibility property of soft tissue, lateral displacements can be reconstructed from axial strain measurements. Results of simulations and experiments on gelatin-based tissue equivalent phantoms are compared with theoretical displacements, as well as estimates derived from traditional speckle tracking. Incompressibility processing greatly improves the accuracy and signal-to-noise ratio (SNR) of lateral displacement measurements compared with more traditional speckle tracking

Mark A. Lubinski; Stanislav Y. Emelianov; K. R. Raghavan; Andrew E. Yagle; Andrei R. Skovoroda; Matthew O'Donnell

1996-01-01

97

Captura de satélites durante a formação de Júpiter  

NASA Astrophysics Data System (ADS)

O planeta Jupiter apresenta um grande número de satélites irregulares. As características das órbitas destes objetos indicam que os mesmos não teriam se formado ao redor do planeta que se encontram. As teorias existentes são de que estes objetos teriam se formado em uma região distante do planeta e sua evolução dinâmica os teria levado a uma captura gravitacional pelo planeta. Tendo em vista que o processo de captura gravitacional sem efeitos dissipativos não produz uma captura permanente, estudamos o processo de captura durante o estágio de formação do planeta. Realizamos simulações numéricas para os casos de satélites prógrados e retrógrados que inicialmente se encontram ao redor de Jupiter com sua massa atual e então, evoluimos a integração voltando no tempo de modo que o planeta sofra uma redução em sua massa (de 100% para 10% de sua massa atual) e verificamos o instante em que o satélites escapa do planeta (quando sua energia do problema de dois corpos se torna positiva). Assim, analisando o problema inverso no tempo, obtivemos em qual estágio de formação de Jupiter aquele hipotético satélite teria sido capturado. Os resultados mostram que os satélites retrógrados são capturados assim que entram na região delimitada pela esfera de Hill do planeta, enquanto que os satélites prógrados só são capturados quando entram numa região bem mais próxima ao planeta, uma fração da esfera de Hill.

Winter, O. C.; Vieira Neto, E.; Yokoyama, T.

2003-08-01

98

Coherent turbulence structures in lateral separation eddies  

NASA Astrophysics Data System (ADS)

An abrupt expansion in channel width generally produces lateral flow separation. A zone of recirculating flow is produced downstream of the point of separation that is termed a lateral separation eddy. Often the abrupt expansion is preceded upstream by a rapid constriction of the channel width. Lateral separation eddies are common in the Colorado River in Grand Canyon downstream of tributary debris fans. They are also produced by spur dikes, which are engineering structures designed to promote lateral sedimentation and eliminate lateral channel migration. Accurate prediction of the sediment transport field in a lateral separation eddy is difficult because of the presence of large and energetic turbulence structures. We have produced a three-dimensional numerical model of turbulence employing the large eddy simulation (LES) technique, in which large scale turbulence is directly calculated by integration of the spatially-filtered Navier-Stokes equations. Our model employs a moving boundary-fitted coordinate system to capture the irregular geometry of the channel and the moving free water surface. The model was used to simulate the flow and large-scale turbulence structures downstream of a single spur dike and in the Thirty Mile lateral separation eddy in Grand Canyon. The lambda-2 technique was used to extract and visualize the large-scale vortices. In both simulations, the upstream channel constriction produces strong secondary circulation resulting in a large vortex core in the main channel flow that is oriented downstream. Past the point of separation, vertical Kelvin-Helmholtz vortex cores are periodically produced along the free shear layer in both simulations. In the spur-dike simulation, the vertical Kelvin-Helmholtz vortex cores interact with the downstream-directed vortex core to produce regularly-shaped vortex cores which periodically give rise to strong, near-bed, cross-stream velocities directed toward the zone of flow reattachment. In the Grand Canyon simulation, the vertical cores and downstream core interact to produce highly irregularly- shaped vortex cores and episodic strong near-bed velocities directed into the lateral separation zone. Presumably, these periodic and episodic, near-bed, cross-stream velocities are important for the flux of sediment into a lateral separation eddy.

Schmeeckle, M. W.; Akahori, R.

2007-12-01

99

Lateral restraint assembly for reactor core  

DOEpatents

A restraint assembly for use in restraining lateral movement of a reactor core relative to a reactor vessel wherein a plurality of restraint assemblies are interposed between the reactor core and the reactor vessel in circumferentially spaced relation about the core. Each lateral restraint assembly includes a face plate urged against the outer periphery of the core by a plurality of compression springs which enable radial preloading of outer reflector blocks about the core and resist low-level lateral motion of the core. A fixed radial key member cooperates with each face plate in a manner enabling vertical movement of the face plate relative to the key member but restraining movement of the face plate transverse to the key member in a plane transverse to the center axis of the core. In this manner, the key members which have their axes transverse to or subtending acute angles with the direction of a high energy force tending to move the core laterally relative to the reactor vessel restrain such lateral movement.

Gorholt, Wilhelm (San Diego, CA); Luci, Raymond K. (Del Mar, CA)

1986-01-01

100

Relationship between childhood growth and later outcomes.  

PubMed

Many studies in different settings and times provided us with enough evidence of the association between environmental exposures (mainly nutrition) during pregnancy/infancy and later health outcomes, such as adult non-communicable diseases (NCDs). An individual with a given susceptibility will continue to experience new environmental challenges (e.g. growth), and these later experiences will modulate the early ones. Children that are thin in infancy and then become larger are at greater risk for later NCD. Studies demonstrated that rapid weight gain is a strong predictor of later NCD, independently of the birthweight. But which periods imply a greater risk for developing NCD? Two periods in the first years of life have been linked to the early obesity onset: the first 6 months and between 2 and 5 years of age. And when do these later health outcomes appear? The literature suggests that they start long before adulthood. Children with rapid weight gain have greater risk for hypertension and cardiovascular disease in the first years of life. These lines of evidence suggest that future research should be committed with educational programs and preventive actions focusing on better life behavior in childhood, adolescence and pregnancy. PMID:23502154

Ferraro, Alexandre Archanjo; Bechere Fernandes, Maria Teresa

2013-01-01

101

Lateral meniscus and lateral femoral condyle cartilage injury by retained cement after medial unicondylar knee arthroplasty.  

PubMed

The authors experienced an unusual case of a patient with a complex tear of the lateral meniscus and adjacent lateral femoral condyle cartilage injury in the contralateral compartment by retained cement, possibly located at the posteromedial side of the medial tibial component after unicondylar knee arthroplasty. Arthroscopic partial meniscectomy and cartilage microfracture were successfully performed. Two small cement fragments were removed from the posterolateral compartment. A sharp pain in the lateral side disappeared postoperatively and posterior knee pain was much reduced. PMID:18534478

Jung, Kwang Am; Lee, Su Chan; Song, Moon Bok

2008-10-01

102

Transforaminal arthroscopic decompression of lateral recess stenosis.  

PubMed

The purpose of this study was to evaluate the feasibility and efficacy of arthroscopic decompression of lateral recess stenosis, determine potential associated complications, and present an alternative method to access the lateral recess of the lumbar spine. Forty patients were selected in whom the authors found clinical and computerized tomography evidence of lateral recess stenosis and sequestered foraminal herniations. All 40 were treated with a posterolateral arthroscopic technique, and 38 were available for this follow-up evaluation. A satisfactory result was obtained in 31 patients (82%). No neurovascular complications were encountered; however, other complications included an infection of the disc space in one patient and a causalgic-type pain in the involved extremity in four patients. The associated postoperative morbidity in this group of patients was minimal and resulted in rapid rehabilitation and return of patients to preoperative functioning level. PMID:8609559

Kambin, P; Casey, K; O'Brien, E; Zhou, L

1996-03-01

103

Measurement of lateral straggling using a microbeam  

NASA Astrophysics Data System (ADS)

An original method has been developed to measure the lateral straggling of sub-micron proton and alpha beams after passing through polymer foils of different thickness. For this purpose, the microbeam line at CENBG has been used in scanning transmission ion microscopy (STIM) configuration to deliver the ions in normal incidence on foils. The lateral spreading of the beam was measured using a collimated charged particle detector centred on the beam axis and placed 6.3 mm behind the foil. When the beam was horizontally scanned in front of the collimator, its lateral distribution was measured step by step detecting particles passing trough the small aperture. Regular gaussian shapes were obtained and data were compared to the result of simulations carried out using the SRIM Monte-Carlo code for 2.5 MeV protons and alphas in Mylar and Formvar thin films.

Michelet, C.; Moretto, Ph; Laurent, G.; Przybylowicz, W. J.; Prozesky, V. M.; Pineda, C. A.; Barberet, Ph; Lhoste, F.; Kennedy, J.

2001-07-01

104

Recovery of Dysphagia in Lateral Medullary Stroke  

PubMed Central

Lateral medullary stroke is typically associated with increased likelihood of occurrence of dysphagia and exhibits the most severe and persistent form. Worldwide little research exists on dysphagia in brainstem stroke. An estimated 15% of all patients admitted to stroke rehabilitation units experience a brainstem stroke out of which about 47% suffer from dysphagia. In India, a study showed that 22.3% of posterior circulation stroke patients develop dysphagia. Dearth of literature on dysphagia and its outcome in brainstem stroke particularly lateral medullary stroke motivated the author to present an actual case study of a patient who had dysphagia following a lateral medullary infarct. This paper documents the severity and management approach of dysphagia in brainstem stroke, with traditional dysphagia therapy and VitalStim therapy. Despite being diagnosed with a severe form of dysphagia followed by late treatment intervention, the patient had complete recovery of the swallowing function.

Gupta, Hitesh; Banerjee, Alakananda

2014-01-01

105

Knee ligament injury during lateral impact.  

PubMed

A volunteer woman subject incurred injury to her right knee consisting of a torn anterior cruciate ligament and stretched medial collateral ligament during a lateral (+Gy) impact test. Similar injury has not been reported in the English-language literature an accidental sideward automotive crashes or lateral impact experimentation involving humans. The primary mechanism which produced this injury was external tibial rotation on the femur with the knee flexed. The factors contributing to the injury included extraordinarily forceful leg bracing by the subject, her knee joint laxity or hypermobility, and the absence of side supports to limit lower extremity flailing during the impact response. In future lateral impact tests, women subjects should be used with caution and any subject with abnormal joint mobility should be excluded from participation. PMID:3977801

Hearon, B F; Brinkley, J W; Raddin, J H; Fleming, B W

1985-01-01

106

Lateral flow immunoassay using magnetoresistive sensors  

NASA Astrophysics Data System (ADS)

Magnetic particles have been adapted for use as labels in biochemical lateral flow strip tests. Standard gold particle lateral flow assays are generally qualitative; however, with magnetic particles, quantitative results can be obtained by using electronic detection systems with giant magnetoresistive (GMR) sensors. As described here, these small integrated sensor chips can detect the presence of magnetic labels in capture spots whose volume is approximately 150 ?m×150 ?m×150 ?m. The range of linear detection is better than two orders of magnitude; the total range is up to four orders of magnitude. The system was demonstrated with both indirect and sandwich enzyme-linked immunosorbent assays (ELISAs) for protein detection of rabbit IgG and interferon-?, respectively, achieving detection of 12 pg/ml protein. Ultimately, the goal is for the detector to be fully integrated into the lateral flow strip backing to form a single consumable item that is interrogated by a handheld electronic reader.

Taton, Kristin; Johnson, Diane; Guire, Patrick; Lange, Erik; Tondra, Mark

2009-05-01

107

Lateral jet injection into swirling combustor flowfields  

NASA Technical Reports Server (NTRS)

An experimental program has been conducted to ascertain the effects of the number of lateral jets, the jet velocity ratio, and the crossflow swirl strength, on the isothermal flowfield patterns in jets injected normally to a round-section crossflow. Attention has been given to the trajectory, penetration, and mixing efficiency of the lateral injection, using flow visualization, pitot-probe and hot-wire methods. In addition, such predictive techniques as a simple, explicit, fully three-dimensional turbulent computer code have been employed.

Lilley, David G.

1988-01-01

108

Dermatomal sensory manifestations in lateral medullary infarction.  

PubMed

A 61-year-old man who experienced a sudden onset of unstable gait followed by nuchal pain was admitted to our department. The neurologic examination revealed right-sided limb ataxia, right partial ptosis, and decreased sensation to 50% of the normal side to pinprick and temperature stimuli on the left side below the level of the T-6 dermatome. A lateral medullary infarction caused by spontaneous vertebral artery dissection was diagnosed by magnetic resonance imaging and computed tomography angiography. In conclusion, lateral medullary infarction is an important entity to consider in the differential diagnosis of dermatomal sensory manifestations. PMID:23099044

Hongo, Hiroki; Tanaka, Yasutaka; Shimada, Yoshiaki; Tanaka, Ryota; Hattori, Nobutaka; Urabe, Takao

2014-01-01

109

Oxidative Pathology in Amyotrophic Lateral Sclerosis  

Microsoft Academic Search

1. CLINICAL INTRODUCTION Amyotrophic lateral sclerosis (ALS) is a devastating neurological disease caused by death of motor neurons in the brain and spinal cord. Its essential clinical aspect is unrelenting paralysis that usually begins focally and then spreads. Most cases of ALS reveal evidence of concurrent corticospinal (upper) and spinal (lower) motor neuron death. The mean age of onset in

Robert H. Brown

110

The lateral approach to laparoscopic splenectomy  

Microsoft Academic Search

BackgroundLaparoscopic splenectomy has been shown to result in shorter hospital stays and a quicker return to work than conventional splenectomy. Having tried the anterior 5 trocar approach, we developed a 4 trocar lateral approach and now present our experience with 22 cases.

Adrian Park; Michel Gagner; Alfons Pomp

1997-01-01

111

Bacterial Sex: Playing Voyeurs 50 Years Later  

Microsoft Academic Search

The concept of chromosomes with a ring structure was born during the early studies of bacterial sexuality, and the discovery of fertility factors-episomes or plasmids-provided much later the key tools for gene cloning and biotechnology. But the plasmid-mediated transfer of antibiotic and other resistances, as well as pathogenicity, has served bacteria well in their own adaptive evolution.

Masamichi Kohiyama; Sota Hiraga; Ivan Matic; Miroslav Radman

2003-01-01

112

Proportioning the airplane for lateral stability  

NASA Technical Reports Server (NTRS)

Proportioning for lateral aircraft control included: (1) directional stability (slope of curve of yawing moment coefficient against sideslip), and (2) effective dihedral factor (slope of curve of rolling moment coefficient against sideslip). Basic forces influencing the directional stability of aircraft are indicated. Propeller side force, basic fuselage yaw, and vertical tail side force contributed to yaw moment about center of gravity.

Donlan, C. J.

1976-01-01

113

Monozygous Twins Discordant for Amyotrophic Lateral Sclerosis  

Microsoft Academic Search

A pair of identical female twins were discordant for amyotrophic lateral sclerosis. The affected twin was not breast-fed; was bitten by a poisonous snake, and was operated on for struma. She had more infections than her sister but no fractures. Her plasma insulin response to glucose loading was also higher. The twins lived separated in their early childhood.Copyright © 1978

M. Jokelainen; J. Palo; J. Lokki

1978-01-01

114

Electroencephalographic laterality changes during human sexual orgasm  

Microsoft Academic Search

Left and right parietal EEGs were recorded while seven subjects experienced sexual climax through self-stimulation. EEG data were quantified by continuous cumulated measurements of the integrated areas of EEG recording during successive 1-sec epochs. In eight out of 12 experiments, this measure revealed a statistically significant change in laterality. Controlled replications with two of the original subjects obviated the possibility

Harvey D. Cohen; Raymond C. Rosen; Leonide Goldstein

1976-01-01

115

Laterality, Implicit Memory, and Attention Disorder.  

ERIC Educational Resources Information Center

Presents study showing children with behaviors characteristic of attention disorder/hyperactivity deficit and high intelligence have more mixed laterality and allergies. Finds these children gather and use more diverse nonverbal and poorly focused information. Concludes such children use uncommon information when exhibiting novelty in nonverbal…

Shaw, Geraldine A.; Brown, Geoffrey

1991-01-01

116

Childhood Victimization; Early Adversity, Later Psychopathology.  

National Technical Information Service (NTIS)

Childhood physical abuse, sexual abuse, and neglect have both immediate and long-term effects. Different types of abuse have a range of consequences for a childs later physical and psychological well-being, cognitive development, and behavior. But there i...

C. S. Widom

2000-01-01

117

Salvage Surgery for Lateral Tennis Elbow  

Microsoft Academic Search

We undertook a retrospective analysis of 34 patients (35 elbows) who had prior failed surgical intervention for lateral tennis elbow. Revision surgeries were per formed between 1979 and 1994. Each patient's non operative and operative history was recorded before our salvage revision surgery. At revision surgery, find ings included residual tendinosis of the extensor carpi radialis brevis tendon in 34

Scott W. Organ; Robert P. Nirschl; Barry S. Kraushaar; Eric J. Guidi

1997-01-01

118

Lateral capacity of helical piles in clays  

SciTech Connect

Helical piles, also known as screw anchors, consist of one or more helical-shaped circular plates welded to a central steel shaft at a specified spacing. Currently, helical piles are being used as tower foundations on land and in offshore areas to secure moorings, cables, and sea-bed pipelines to the sea bed. In this paper, the behavior of helical piles under lateral loads in clayey soils is examined through an experimental investigation on model piles. Tests were conducted on rigid helical piles with different numbers of plates. Model anchors were made of 13.8 mm diameter mild steel shafts to which mild steel plates of 33 mm diameter were welded. For comparison, a single straight shaft with a diameter of 13.8 mm was also tested. Test results revealed that the lateral capacity of helical piles is greater than that of straight shaft piles. A simple theoretical model is suggested to estimate the lateral capacity of rigid helical piles. The theoretical model suggested incorporates lateral resistance of the soil on the shaft, bearing resistance on the bottom of the helical plate, uplift resistance on the top of the helical plate, and frictional resistance on the surface of the helical plate. The validity of this model is examined.

Prasad, Y.V.S.N. [Memorial Univ. of Newfoundland, St. John`s, Newfoundland (Canada). Faculty of Engineering and Applied Science] [Memorial Univ. of Newfoundland, St. John`s, Newfoundland (Canada). Faculty of Engineering and Applied Science

1996-11-01

119

New lateral stabilizing device for airplanes  

NASA Technical Reports Server (NTRS)

The proposed device tends to render the lateral stabilization of airplanes easier and more efficacious. The proposed solution is to mount the ailerons independently, in such a manner that they can turn freely, under the action of the relative wind, about an axis located in front of the extreme position of the center of the lift.

Constantin, Louis

1923-01-01

120

Atretic cephalocele communicating with lateral ventricles  

Microsoft Academic Search

Atretic cephaloceles are thought to be involuted true meningoceles or encephaloceles. They are located at the midline of the parietal or occipital region and usually joined to the subarachnoidal space. We present a 6-month-old girl with atretic cephalocele communicating with the lateral ventricles.

M. D. Aydin

2001-01-01

121

Lateral Jet Control for Tactical Missiles.  

National Technical Information Service (NTIS)

The aim of this paper is to give a survey of lateral jets as control system of tactical missiles. The paper is divided into four parts. The first part gives a brief analysis of new control requirements pertaining to tactical missiles, presents the advanta...

P. Champigny R. G. Lacau

1994-01-01

122

Lateralized Anomalous Perceptual Experiences in Schizophrenia  

Microsoft Academic Search

Four cases of schizophrenia are described, in which subjects reported anomalous perceptual experiences confined to one visual field, in all cases the left visual field. The pattern, content and laterality of such anomalous perceptions point to the presence of right hemisphere dysfunction in schizophrenia. Further evidence to this effect comes from examining the type of anomalous perceptual experiences reported by

R. Persaud; J. Cutting

1991-01-01

123

Lateralization of Norepinephrine in Human Thalamus  

Microsoft Academic Search

Norepinephrine has a strongly lateralized distribution in the human thalamus. In the pulvinar region the left hemisphere is rich in norepinephrine, whereas in the somatosensory input area the right hemisphere has a higher concentration of this catecholamine. Such naturally occurring left-right differences in concentration of a neurotransmitter represent a new aspect of hemispheric specialization.

Arvin Oke; Richard Keller; Ivan Mefford; Ralph N. Adams

1978-01-01

124

Profiling 1366 Technologies: One Year Later  

SciTech Connect

Last January, we took a look at how ARPA-E performer, 1366 Technologies is working to dramatically reduce the cost of solar energy. A year later, we revisited their headquarters in Lexington, MA to see the progress they've made.

Van Mierlo, Frank; Sachs, Ely

2011-01-01

125

Motor laterality in 4 breeds of dog  

Microsoft Academic Search

The aim of the current study was designed to explore possible breed differences in a basic behavioral phenotype in dogs. It measured paw use during food-retrieval from a cylindrical, hollow, rubber toy to assess motor laterality (pawedness) in 4 breeds of dogs selected for their morphological differences: 45 greyhounds (males n = 23\\/females n = 22), 47 whippets (15\\/32), 46

Paul D. McGreevy; Alex Brueckner; Peter C. Thomson; Nicholas J. Branson

2010-01-01

126

Biphasic cell responses on laterally mobile films  

NASA Astrophysics Data System (ADS)

The engineering of polymer surfaces or matrices that are capable of controlling cell adhesion has been widely explored. In nearly all of these works, the polymer chains (and ligands) are chemically attached to the underlying substrate, and therefore these systems are inherently static. By contrast, cellular environments such as the extracellular matrix (ECM) are dynamic and remodeled by biochemical reactions and biophysical forces. Borrowing this concept from Nature, we created polymer films by an interfacial self-assembly process, whereby individual chains can exhibit lateral mobility (in-plane diffusive motion). NIH 3T3 fibroblasts seeded on such RGD-presenting polymer films show biphasic responses in spreading and adhesion strength to lateral mobility, with a minimal response for intermediate mobility values. Futhermore, preliminary immuno-staining experiments reveal that the total area of focal adhesions demonstrates a similar biphasic trend to the cellular-scale behaviors. In contrast, actin filaments or stress fibers appear to be unaffected by the substrate lateral mobility. These results show that lateral mobility is an important, although not fully explored aspect of mechano-sensing by cells, and can potentially give new perspectives on cell-ECM interactions.

Kourouklis, Andreas; Lerum, Ronald; Bermudez, Harry

2013-03-01

127

Skin involvement in amyotrophic lateral sclerosis  

Microsoft Academic Search

SummaryBackground Patients with sporadic amyotrophic lateral sclerosis (ALS) show disorganised collagen and elastin of the dermis. We looked for inflammatory alterations to cutaneous blood vessels.Patients and findings Seven patients with sporadic ALS were investigated; five were confined to bed, but none had bedsores. Light and electron microscopy of skin showed an oedematous dermis with collagen fibrils of irregular diameter. Small

G Kolde; R Bachus; A. C Ludolph

1996-01-01

128

Later life, inequality and sociological theory  

Microsoft Academic Search

A central concern of many theorists of later life has been to elucidate the processes which shape the marginalisation and relative disadvantage of older people in contemporary society. This concern parallels a current argument within sociological theorising: that life course stage and generational location constitute increasingly important dimensions of social dierence and inequality. It is an argument of the paper

SARAH IRWIN

1999-01-01

129

CORTICAL CELL DEATH DURING LATERAL ROOT FORMATION  

Microsoft Academic Search

Root segments of Convolvulus arvensis, the field bindweed, were examined with the electron microscope to make possible a description of the fine structural correlates of lateral root protrusion through cortical parenchyma. Particular attention was directed to the outermost primordium cells, derived by meristematic activity from the endodermis, and to the con- tiguous cortical parenchyma cells. By following the fate of

HOWARD T. BONNETT

1969-01-01

130

The Columbine Tragedy Ten Years Later  

ERIC Educational Resources Information Center

Some tragedies are so emblazoned in people's minds that years later they can recall where they were when they first heard the news. The assassinations of John F. Kennedy and Martin Luther King Jr., the Challenger explosion, and the Sept. 11 terrorist attacks are among these events. So also is the Columbine High School tragedy of April 20, 1999.…

Hammond, Jane

2009-01-01

131

Profiling 1366 Technologies: One Year Later  

ScienceCinema

Last January, we took a look at how ARPA-E performer, 1366 Technologies is working to dramatically reduce the cost of solar energy. A year later, we revisited their headquarters in Lexington, MA to see the progress they've made.

Van Mierlo, Frank; Sachs, Ely;

2013-05-29

132

Cooling Therapy Helps Newborns Years Later  

MedlinePLUS

... Helps Newborns Years Later High Blood Pressure in Children Featured Website: Impact of NIH Research Links Labor and Birth (HHS) Cold Treatment Protects Against Infant Disability and Death From Oxygen Loss Cerebral Palsy CONTACT US NIH Office of Communications and Public ...

133

Focus on Spacetime 100 Years Later  

Microsoft Academic Search

Among the remarkable new ideas that Einstein introduced into physics in 1905 was the revision of our concept of space and time. His special theory of relativity quickly became incorporated into all of physics. This cannot be said of his later general relativity, the ultimate outgrowth of his original insight 100 years ago. In the general theory, curvature of Einsteinian

Richard Price; Jorge Pullin

2005-01-01

134

F35% Revisited Ten Years Later  

Microsoft Academic Search

This paper reviews the original derivation of the F35% (later F40%) harvest strategy, which consists of fishing at a rate that reduces spawning biomass per recruit to 35% (or 40%) of the unfished value, and investigates its applicability to long-lived stocks with low resiliency, such as some of the Pacific Coast rockfishes Sebastes spp. The life history parameters are unimportant

William G. Clark

2002-01-01

135

Risk factors for suicide in later life  

Microsoft Academic Search

Suicide rates are higher in later life than in any other age group. The design of effective suicide prevention strategies hinges on the identification of specific, quantifiable risk factors. Methodological challenges include the lack of systematically applied terminology in suicide and risk factor research, the low base rate of suicide, and its complex, multidetermined nature.Although variables in mental, physical, and

Yeates Conwell; Paul R. Duberstein; Eric D. Caine

2002-01-01

136

Profiling 1366 Technologies: One Year Later  

ScienceCinema

Last January, we took a look at how ARPA-E performer, 1366 Technologies is working to dramatically reduce the cost of solar energy. A year later, we revisited their headquarters in Lexington, MA to see the progress they've made.

137

Thrust Vectoring for Lateral-Directional Stability.  

National Technical Information Service (NTIS)

The advantages and disadvantages of using thrust vectoring for lateral-directional control and the effects of reducing the tail size of a single-engine aircraft were investigated. The aerodynamic characteristics of the F-16 aircraft were generated by usin...

L. R. Peron T. Carpenter

1992-01-01

138

Preparing Future Faculty: Ten Years Later  

ERIC Educational Resources Information Center

When Sean Murphy designed the Graduate Student Internship Program at the College of Lake County (CLC), his 2001 TETYC article about the then two-year-old program detailed his programmatic response to the job market. Ten years later, the CLC-DePaul University partnership remains the strongest of the original dozen cross-sector relationships CLC…

Murphy, Sean P.; Aiossa, Elizabeth; Winter, Mary Mugica

2010-01-01

139

Lateral Load Behavior of Drilled Shafts.  

National Technical Information Service (NTIS)

Drilled shaft foundations, used extensively to support highway structures, are often subjected to both axial and lateral loads. To obtain a safe and economical design, the response of the soil to the applied loads must be known. In this study, currently a...

L. C. Reese R. C. Welch

1972-01-01

140

Modeling lateral attenuation of aircraft flight noise  

NASA Astrophysics Data System (ADS)

To calculate the airbase and/or airport noise exposure at any specified ground position located to the side of a flight path, a variety of noise attenuation mechanisms must be accounted for if the model is to predict levels that are in reasonable agreement with field noise measurements. For civil aircraft the lateral attenuation model developed by the Society of Automotive Engineers, Inc. A-21 Committee on Aircraft Noise is commonly used. Since it was derived mainly from measured lateral attenuation data on civil aircraft, the predicted results generally show good agreement when compared with actual measurements. However, the frequency spectra of the noise from most military aircraft is often quite different from that associated with civil transports. A series of field experiments was conducted to develop a data base of sufficient size (853 points at elevation angles aranging from 1.9 to 90 degrees) to accurately model the lateral attenuation associated with military flights near airbases and especially along Military Training Routes where the aircraft fly at low altitude (150 m or less) and at high subsonic airspeeds. Those tests confirmed the need for a different model of lateral attenuation for typical United States military versus civil aircraft flight operations. A companion paper, A Prediction Model for Noise From Low-Altitude Military Aircraft, describes recent tests performed in the United Kingdom. Two of the aircraft (F-15 and F-16) were common to the tests performed in the United States and the United Kingdom. This paper merges the 182 data points at very low elevation angles (1.3 to 6.8 degrees) from the UK tests, adds 154 more USAF data points at low to moderate elevation angles (3 to 45 degrees) and derives an improved model for lateral attenuation associated with military aircraft.

Speakman, J. D.; Berry, B. F.

141

Visual lateralization and homing in pigeons.  

PubMed

The aim of our study was to analyse the components of visual lateralization in pigeon homing, a large-scale spatial task. In a series of 13 releases, birds were tested as binocular controls or monocularly with the right or left-eye covered. Occlusion of either eye had a significant effect on initial orientation and homing performance. Vanishing bearings were deflected to the side of the open eye, vanishing intervals were longer, and homing speed was reduced. These parameters were affected to a different degree. Initial orientation was markedly lateralized, with birds using their right-eye deviating less from the mean of control birds and showing significantly less variance. One minute after release, the deviation and variance were similarly large in both monocular groups. However, while the right-eyed birds improved their performance until leaving the release site, the left-eyed birds failed to do so. Vanishing intervals were similar in both monocular groups, but homing speed was reduced to a lesser extent in pigeons using the right-eye. The degree of lateralization varied across different releases, but superiority of the right-eye/left hemisphere prevailed. Lateralization did not depend on familiarity with the release site. This suggests that the crucial processes involved the eyes, but did not depend on visual memory of landscape features at the release site. Results reveal, for the first time, asymmetries of directional orientation as an essential component of lateralized homing performance. As likely mechanisms we suggest hemispheric differences in magnetic compass orientation and in the adjustment to optic flow. PMID:15313017

Prior, Helmut; Wiltschko, Roswitha; Stapput, Katrin; Güntürkün, Onur; Wiltschko, Wolfgang

2004-10-01

142

Bilateral osteochondritis dissecans of the lateral femoral condyle following bilateral total removal of lateral discoid meniscus: a case report  

Microsoft Academic Search

Osteochondritis dissecans (OCD) of the lateral femoral condyle sometimes occurs with a discoid lateral meniscus. Recently,\\u000a it was reported that OCD of the lateral femoral condyle occurred after total removal of the lateral meniscus. We report the\\u000a case of a 12-year-old boy with bilateral OCD of the lateral femoral condyle following bilateral total removal for discoid\\u000a lateral meniscus. Valgus deviation

Yusuke Hashimoto; Gen Yoshida; Tomohiro Tomihara; Takeshi Matsuura; Shinji Satake; Kunikazu Kaneda; Nagakazu Shimada

2008-01-01

143

Lateral root development in the maize (Zea mays) lateral rootless1 mutant  

PubMed Central

Background and Aims The maize lrt1 (lateral rootless1) mutant is impaired in its development of lateral roots during early post-embryonic development. The aim of this study was to characterize, in detail, the influences that the mutation exerts on lateral root initiation and the subsequent developments, as well as to describe the behaviour of the entire plant under variable environmental conditions. Methods Mutant lrt1 plants were cultivated under different conditions of hydroponics, and in between sheets of moist paper. Cleared whole mounts and anatomical sections were used in combination with both selected staining procedures and histochemical tests to follow root development. Root surface permeability tests and the biochemical quantification of lignin were performed to complement the structural data. Key Results The data presented suggest a redefinition of lrt1 function in lateral roots as a promoter of later development; however, neither the complete absence of lateral roots nor the frequency of their initiation is linked to lrt1 function. The developmental effects of lrt1 are under strong environmental influences. Mutant primordia are affected in structure, growth and emergence; and the majority of primordia terminate their growth during this last step, or shortly thereafter. The lateral roots are impaired in the maintenance of the root apical meristem. The primary root shows disturbances in the organization of both epidermal and subepidermal layers. The lrt1-related cell-wall modifications include: lignification in peripheral layers, the deposition of polyphenolic substances and a higher activity of peroxidase. Conclusions The present study provides novel insights into the function of the lrt1 gene in root system development. The lrt1 gene participates in the spatial distribution of initiation, but not in its frequency. Later, the development of lateral roots is strongly affected. The effect of the lrt1 mutation is not as obvious in the primary root, with no influences observed on the root apical meristem structure and maintenance; however, development of the epidermis and cortex are impaired.

Husakova, Eva; Hochholdinger, Frank; Soukup, Ales

2013-01-01

144

The treatment of lateral clavicle fractures.  

PubMed

This study assesses the results of surgical treatment of 15 displaced Neer type II fractures of the lateral clavicle in 15 patients, which occurred between November 1988 and March 1995 and which were followed up for a mean period of 4.6 years (range 2-9 years). The patients fell into two groups, one 'acute group' and one 'non-union' group. Patients treated initially by a non-operative approach had suffered prolonged morbidity and time off work prior to and after surgery. The ultimate result was good. The fixation used was a Dacron arterial graft as a sling around the clavicle and coracoid process. Delayed (non-union) cases were augmented with bone graft and inter-fragmentary screw fixation. All fractures eventually united. We question the place of prolonged non-operative management in the treatment of displaced Neer type II fractures of the lateral clavicle. PMID:10704582

Webber, M C; Haines, J F

2000-04-01

145

High performance silicon lateral PIN photodiode  

NASA Astrophysics Data System (ADS)

Start Photodetectors with high responsivity in Si-related processes are required for high speed optoelectronic applications such as fiber optic data communication systems. In this paper, the performance of a virtual lateral PIN photodiode with intensity response in the 200-1000 nm wavelength range was demonstrated. The results obtained for responsivity, total quantum efficiency and frequency response were 0.62 A/W and 13.1 GHz respectively for design parameters of intrinsic region length of 6 ?m, photoabsorption layer thickness of 50 ?m, incident optical power of 1 mW/cm2 and bias voltage of 3 V. As a conclusion, the decrease in device size enabled the realization of a high performance lateral p-i-n photodiode.

Kalthom Tasirin, S.; Susthitha Menon, P.; Ahmad, Ibrahim; Fazlili Abdullah, S.

2013-06-01

146

Thrust vectoring for lateral-directional stability  

NASA Technical Reports Server (NTRS)

The advantages and disadvantages of using thrust vectoring for lateral-directional control and the effects of reducing the tail size of a single-engine aircraft were investigated. The aerodynamic characteristics of the F-16 aircraft were generated by using the Aerodynamic Preliminary Analysis System II panel code. The resulting lateral-directional linear perturbation analysis of a modified F-16 aircraft with various tail sizes and yaw vectoring was performed at several speeds and altitudes to determine the stability and control trends for the aircraft compared to these trends for a baseline aircraft. A study of the paddle-type turning vane thrust vectoring control system as used on the National Aeronautics and Space Administration F/A-18 High Alpha Research Vehicle is also presented.

Peron, Lee R.; Carpenter, Thomas

1992-01-01

147

Polarization phase shifting lateral shearing interferometer  

NASA Astrophysics Data System (ADS)

A polarization phase shifting lateral shearing interferometer based on a polarization beam splitting plate(PBSP) is proposed. The front surface of the PBSP is coated with polarization beam splitting film and its back surface is coated with total reflection film. The beam to be tested is split by the PBSP with an incidence angle of 45° and divided into two mutually perpendicular linearly polarization beams. Phase shifting can be introduced to the interferometer when the PBSP is combined with a polarzation temporal or spatial phase shifter. A polarizaiton temporal phase shifting lateral shearing interferometer system is built up both with the ASAP software and the experiments. The usefulness of the interferometer is verified.

Liu, Lei; Zeng, Aijun; Zhu, Linglin; Song, Qiang; Huang, Huijie

2013-08-01

148

Segond fracture: lateral capsular ligament avulsion.  

PubMed

Recently, there has been an emphasis placed on incorporating fundamental radiology in graduate level physical therapy curricula; however, the majority of practicing physical therapists never received formal radiology instruction. As health care changes, so must the role of the physical therapist. In a managed care environment, it is essential that physical therapists recognize basic radiographic findings and understand their clinical ramifications. The purpose of this article is to review the literature and provide commentary on avulsion fractures of the lateral tibial condyle, known as Segond fractures. Segond fractures typically occur by forced internal tibial rotation with the knee flexed. This mechanism placed tremendous force on the middle portion of the lateral capsule and associated meniscotibial ligament and results in a small bony avulsion. The Segond fracture is an important radiographic sign that is critical to recognize because it is generally associated with anterior cruciate ligament disruption. PMID:9007767

Davis, D S; Post, W R

1997-02-01

149

Season of birth in amyotrophic lateral sclerosis.  

PubMed

While studying birth cohort issues, the authors focused also on the seasons of birth in amyotrophic lateral sclerosis (ALS). The analyses were based on computerized death records of Swiss mortality statistics 1969-1993. The results confirm an excess of births in spring months. They suggest that risk factors in ALS can be acquired very early in life, thus introducing a long latency period. PMID:9690754

Ajdacic-Gross, V; Wang, J; Gutzwiller, F

1998-06-01

150

Lateral dampers for thrust bearings. Final Report  

SciTech Connect

The development of lateral damping schemes for thrust bearings was examined, ranking their applicability to various engine classes, selecting the best concept for each engine class and performing an in-depth evaluation. Five major engine classes were considered: large transport, military, small general aviation, turboshaft, and non-manrated. Damper concepts developed for evaluation were: curved beam, constrained and unconstrained elastomer, hybrid boost bearing, hydraulic thrust piston, conical squeeze film, and rolling element thrust face.

Hibner, D.H.; Szafir, D.R.

1985-08-01

151

Lateral–distortional buckling of monorails  

Microsoft Academic Search

This paper is concerned with the elastic lateral–distortional (LD) buckling of single span steel monorail I-beams and its influence on their design strengths. The distortion of a slender web reduces the elastic buckling resistance of an intermediate length beam below its flexural–torsional (FT) resistance. A finite element computer program was used to study the elastic LD buckling of single span

N. S. Trahair

2009-01-01

152

Paraoxonase Gene Mutations in Amyotrophic Lateral Sclerosis  

PubMed Central

Three clustered, homologous paraoxonase genes (PON1, PON2 and PON3) have roles in preventing lipid oxidation and detoxifying organophosphates. Recent reports describe a genetic association between the PON genes and sporadic amyotrophic lateral sclerosis (ALS). We now report that in genomic DNA from individuals with familial and sporadic ALS we have identified at least seven PON gene mutations that are predicted to alter PON function.

Ticozzi, Nicola; LeClerc, Ashley Lyn; Keagle, Pamela; Glass, Jonathan D.; Wills, Anne-Marie; van Blitterswijk, Marka; Bosco, Daryl A.; Rodriguez-Leyva, Ildefonso; Gellera, Cinzia; Ratti, Antonia; Taroni, Franco; McKenna-Yasek, Diane M.; Sapp, Peter C.; Silani, Vincenzo; Furlong, Clement E.; Brown, Robert H.; Landers, John E.

2010-01-01

153

LATERAL LAMINATION APPROACH FOR MULTILAYER PIEZOELECTRIC MICROACTUATOR  

Microsoft Academic Search

This paper reports a simple lateral lamination scheme for the fabrication of multilayer piezoelectric actuators. The fabrication scheme consists of dicing of a high-d 33 piezoelectric coefficient lead zirconate titanate (PZT) material, photolithographic high- aspect-ratio SU-8 definition of electrical isolation, and micromolding of conductive polymer electrodes. Backside and inclined UV exposure has been exploited to secure the 1mm-thick SU-8 pillar

Xiaosong Wu; Guang Yuan; Seong-O Choi; Yanzhu Zhao; Seong-Hyok Kim; Yong-Kyu Yoon; Mark G. Allen

154

Lateral situated sinus pericranii. Case report.  

PubMed

We hereby report a case of a laterally situated sinus pericranii, which is rare. According to the articles regarding this kind of lesion, carotid angiograms revealed no pathological findings, and venograms taken with direct injection of contrast medium into the mass were useful. It should be stressed that the lesion could be demonstrated in the late phase of carotid angiograms, and digital subtraction angiography was especially useful for diagnosis. The literature is also reviewed. PMID:2814792

Nishio, A; Sakaguchi, M; Murata, K; Nishikawa, M; Nishimura, S

1989-11-01

155

Giant lateral sinus pericranii. Case report.  

PubMed

A case of giant lateral sinus pericranii, which presented in a patient during early childhood as a soft, collapsible mass and gradually grew until it reached 13 x 9 cm when the patient was 36 years of age, is reported. The patient underwent successful surgery and the lesion was totally excised. The results of diagnostic tests (computerized tomography scanning, magnetic resonance imaging, cerebral angiography, and sinusography) and surgery-related problems are presented and discussed. PMID:9420089

Spektor, S; Weinberger, G; Constantini, S; Gomori, J M; Beni-Adani, L

1998-01-01

156

Symptomatic torn discoid lateral meniscus in adults  

Microsoft Academic Search

The purposes of this study were to report degenerative changes that coexist with a symptomatic torn discoid lateral meniscus\\u000a in adults and to analyze the factors associated with the accompanied degenerative changes. From 1997 to 2008, 329 knees in\\u000a the 305 patients were included. Associations between the status of the meniscus and the coexisting degenerative changes on\\u000a the images and

Jin Hwan Ahn; Sang-Hee Choi; Yong Seuk Lee; Jae Chul Yoo; Moon Jong Chang; Sooho Bae; Young Ryeol Bae

2011-01-01

157

F 35% Revisited Ten Years Later  

Microsoft Academic Search

This paper reviews the original derivation of the F35% (later F40%) harvest strategy, which consists of fishing at a rate that reduces spawning biomass per recruit to 35% (or 40%) of the unfished value, and investigates its applicability to long-lived stocks with low resiliency, such as some of the Pacific Coast rockfishesSebastes spp. The life history parameters are unimportant (at

William G. Clark

2002-01-01

158

Total lateral sphincterotomy for anal fissure  

Microsoft Academic Search

Background and aimsInitial experience with the posterior sphincterotomy for treating anal fissures was unsatisfactory, with a significant rate of recurrences and anal incontinence. This report describes the lateral approach to complete section of the internal sphincter.Patients and methodsBetween 1997 and 2001 we surgically treated 164 patients for anal fissure. Preoperative and postoperative anal manometries were recorded. Postoperative course and early

Adriano Tocchi; Gianluca Mazzoni; Michelangelo Miccini; Diletta Cassini; Elia Bettelli; Stefania Brozzetti

2004-01-01

159

Quantifiable Lateral Flow Assay Test Strips  

NASA Technical Reports Server (NTRS)

As easy to read as a home pregnancy test, three Quantifiable Lateral Flow Assay (QLFA) strips used to test water for E. coli show different results. The brightly glowing control line on the far right of each strip indicates that all three tests ran successfully. But the glowing test line on the middle left and bottom strips reveal their samples were contaminated with E. coli bacteria at two different concentrations. The color intensity correlates with concentration of contamination.

2003-01-01

160

A post-CMOS micromachined lateral accelerometer  

Microsoft Academic Search

In a post-complementary metal-oxide-semiconductor (CMOS) micromachining technology, the process flow enables the integration of micromechanical structures with conventional CMOS circuits which are low-cost and readily available. This paper presents a lateral capacitive sensing accelerometer fabricated in the post-CMOS process. Design advantages include electrically isolated multimetal routing on microstructures to create full-bridge capacitive sensors, and integration to increase transducer sensitivity by

Hao Luo; Gang Zhang; L. Richard Carley; Gary K. Fedder

2002-01-01

161

Regulation of AMPA receptor lateral movements  

NASA Astrophysics Data System (ADS)

An essential feature in the modulation of the efficacy of synaptic transmission is rapid changes in the number of AMPA (?-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid) receptors at post-synaptic sites on neurons. Regulation of receptor endo- and exocytosis has been shown to be involved in this process. Whether regulated lateral diffusion of receptors in the plasma membrane also participates in receptor exchange to and from post-synaptic sites remains unknown. We analysed the lateral mobility of native AMPA receptors containing the glutamate receptor subunit GluR2 in rat cultured hippocampal neurons, using single-particle tracking and video microscopy. Here we show that AMPA receptors alternate within seconds between rapid diffusive and stationary behaviour. During maturation of neurons, stationary periods increase in frequency and length, often in spatial correlation with synaptic sites. Raising intracellular calcium, a central element in synaptic plasticity, triggers rapid receptor immobilization and local accumulation on the neuronal surface. We suggest that calcium influx prevents AMPA receptors from diffusing, and that lateral receptor diffusion to and from synaptic sites acts in the rapid and controlled regulation of receptor numbers at synapses.

Borgdorff, Aren J.; Choquet, Daniel

2002-06-01

162

Laterally-biased quantum dot infrared photodetector  

NASA Astrophysics Data System (ADS)

At the Air Force Research Laboratory, Space Vehicles Directorate, we are interested in improving the performance of or modifying the capabilities of infrared detectors in order to locate and identify dim and/or distant objects in space. One characteristic we are very interested in is multicolor detection. To this end, we have turned to a novel detector design that we have come to call a Lateral Quantum Dot Infrared Photodetector (LQDIP). In this design, InAs quantum dots are buried in a GaAs quantum well, which in turn is tunnel-coupled to another GaAs quantum well. Photoexcited electrons from the quantum dots tunnel over to the second well and are then swept out via a lateral (perpendicular to the growth direction) bias voltage. This architecture should exhibit the ability to tune to select infrared frequencies with reduced dark current and unity gain. The lateral photocurrent is directed by a vertical (parallel to the growth direction) gate voltage. We will discuss this detector architecture and the LQDIP operating principles and conditions, and we will present some preliminary results of current-voltage, photocurrent, differential conductance, and spectral measurements.

Cardimona, D. A.; Morath, C. P.; Guidry, D. H.; Cowan, V. M.

2013-07-01

163

Lateralization of magnetic compass orientation in pigeons  

PubMed Central

The aim of our study was to test for lateralization of magnetic compass orientation in pigeons. Having shown that pigeons are capable of learning magnetic compass directions in an operant task, we wanted to know whether the brain hemispheres contribute differently and how the lateralization pattern relates to findings in other avian species. Birds that had learnt to locate food in an operant chamber by means of magnetic directions were tested for lateralization of magnetic compass orientation by temporarily covering one eye. Successful orientation occurred under all conditions of viewing. Thus, pigeons can perceive and process magnetic compass directions with the right eye and left brain hemisphere as well as the left eye and right brain hemisphere. However, while the right brain hemisphere tended to confuse the learned direction with its opposite (axial response), the left brain hemisphere specifically preferred the correct direction. Our findings demonstrate bilateral processing of magnetic information, but also suggest qualitative differences in how the left and the right brain deal with magnetic cues.

Wilzeck, Christiane; Wiltschko, Wolfgang; Gunturkun, Onur; Wiltschko, Roswitha; Prior, Helmut

2010-01-01

164

Lateral jet injection into typical combustor flowfields  

NASA Technical Reports Server (NTRS)

The experimental problem of lateral jet injection into typical flow fields in the absence of combustion was studied. All flow fields being investigated have no expansion of the crossflow (the test section to swirler diameter ratio D/d = 1), after its passage through an optional swirler (with swirl vane angle phi = 0 (swirler removed), 45, and 70 degree). The lateral jet(s) is(are) located one test-section diameter downstream of the test-section inlet (x/D = 1). The lateral jets have round-sectioned nozzles, each of which has an area of 1/100th of the cross sectional area of the crossflow (A sub j/A sub c = 1/100). Jet-to-crossflow velocity ratios of R = v sub j/u sub o = 2, 4, and 6 were investigated. Helium-bubble low visualization, five-hole pitot probe time-mean velocity measurements, and single-wire time-mean velocity and normal and shear stress turbulence data were obtained in the research program.

Lilley, D. G.

1986-01-01

165

Lateral hypothalamus and sympathetic firing rate.  

PubMed

Measurements of sympathetic firing rate have been made after the acute microinjection of glucose or insulin into the lateral hypothalamic area as well as after ablation of this area with locally injected gold thioglucose. Injection of glucose into the lateral hypothalamus (LH) produced a small but significant and dose-dependent reduction in the firing rate of efferent sympathetic nerves to interscapular brown adipose tissue. Injection of insulin into the same region produced a very short-lived increase in efferent sympathetic firing rate. Bilateral lesions in the lateral hypothalamus produced by microinjection and gold thioglucose lowered body weight more than sham injections into the LH of control animals. There was an increase in basal sympathetic firing rate at 3, 9, and 24 h after LH lesions. There was also an increase in firing rate at 1 and 3 days, but by 7 days firing rate had returned to control levels. The data support the hypothesis that LH lesions enhance sympathetic activity but show only very limited modulation by glucose or insulin. PMID:3137829

Sakaguchi, T; Takahashi, M; Bray, G A

1988-09-01

166

The governance of lateral relations between and within organisations  

Microsoft Academic Search

Recent years have witnessed various changes in organisational structures and seen the increasing importance of lateral relations. The objective of this paper is to explore the nature of lateral relations and to develop a framework for conceptualising the elements of a ‘governance package’ for lateral relationships. Drawing on two illustrations – one of lateral relations between organisations and the other

Jeltje van der Meer-Kooistra; Robert W. Scapens

2008-01-01

167

Glomus tumor of the lateral aspect of the knee joint  

Microsoft Academic Search

Background We report a rare case of glomus tumor that occurred in the lateral joint of the knee. A 54?year?old man was referred to us with a 3?year history of lateral pain in the left knee and the diagnosis of lateral meniscus injury. Physical examination revealed a small trigger point localized just on the lateral joint space. Magnetic resonance imaging

Kohjirou Okahashi; Kazuya Sugimoto; Makoto Iwai; Kouji Kaneko; Masayuki Samma; Yoshiyuki Fujisawa; Yoshinori Takakura

2004-01-01

168

An In Vitro Model to Investigate Filling of Lateral Canals  

Microsoft Academic Search

Aims of this work were to examine lateral canals in extracted teeth, to propose a new technique to produce artificial lateral canals, and to compare two obturation techniques. Cleared roots were examined to record measure and shape of lateral canals. Artificial lateral canals were prepared on human demineralized teeth before final clearing. Specimens were divided in two groups: canals of

Mauro Venturi; Carlo Prati; Lorenzo Breschi

169

AXR1 Acts after Lateral Bud Formation to Inhibit Lateral Bud Growth in Arabidopsis1  

Microsoft Academic Search

The AXR1 gene of Arabidopsis is required for many auxin re- sponses. The highly branched shoot phenotype of mature axr1 mutant plants has been taken as genetic evidence for a role of auxin in the control of shoot branching. We compared the development of lateral shoots in wild-type Columbia and axr1-12 plants. In the wild type, the pattern of lateral

Petra Stirnberg; Steven P. Chatfield; H. M. Ottoline Leyser

1999-01-01

170

Motor neuron disease (amyotrophic lateral sclerosis) arising from longstanding primary lateral sclerosis.  

PubMed Central

Three men were initially diagnosed as having primary lateral sclerosis (PLS), but eventually developed amyotrophic lateral sclerosis (ALS) after 7.5, 9, and at least 27 years. Non-familial ALS and PLS might be different manifestations of a single disease or constitute completely distinct entities. The clinical diagnosis of PLS predicts a median survival that is four to five times longer than in ALS. Images

Bruyn, R P; Koelman, J H; Troost, D; de Jong, J M

1995-01-01

171

Genetic factors and breast cancer laterality  

PubMed Central

Background Women are more likely to develop cancer in the left breast than the right. Such laterality may influence subsequent management, especially in elderly patients with heart disease who may require radiation therapy. The purpose of this study was to explore possible factors for such cancer laterality. Methods In this work, clinical data for consecutive patients with histologically confirmed breast cancer were reviewed, with emphasis on clinical presentation and family history. Results Between 2005 and 2012, 687 patients with breast cancer were seen. Two women with incomplete data and eleven men were excluded. In total, 343 (50.9%) patients presented with left breast cancer, 311 (46.1%) with right breast cancer, and 20 (3.0%) with simultaneous bilateral malignancy. There were no significant differences between the three groups, especially in regards to clinical presentation and tumor characteristics. A total of 622 (92.3%) patients had unilateral primary, 20 (3.0%) had simultaneous bilateral, and 32 (4.7%) had metachronous primary breast cancer with subsequent contralateral breast cancer after 7.5–236 months. The worst 10-year survival was for bilateral simultaneous (18%) compared with unilateral (28%) and metachronous primaries (90%). There were no differences in survival in relation to breast cancer laterality, handedness, and presence or absence of a family history of cancer. There were significant similarities between patients and first-degree relatives in regards to breast cancer laterality, namely same breast (30/66, 45.5%), opposite breast (9/66, 13.6%), and bilateral cancer (27/66, 40.9, P=0.01163). This was more evident among patients and their sisters (17/32, 53.1%) or mothers (11/27, 40.7%, P=0.0689). There were also close similarities in relation to age at initial diagnosis of cancer for patients and their first-degree relatives for age differences of ?5 years (48/166, 28.9%), 6–10 years (34/166, 20.5%), and >11 years (84/166, 50.6%, P=0.12065). Conclusion High similarities between patients and their first-degree relatives in regards to cancer laterality and possibly age at initial diagnosis of cancer may suggest an underlying inherited genetic predisposition.

Amer, Magid H

2014-01-01

172

Involvements of the lateral hypothalamic area in gastric motility and its regulation by the lateral septum.  

PubMed

Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor (GHS-R) pre-dominantly produced in the stomach. Recent studies have shown that it may promote food intake and gastric motility. We aim to explore effects of ghrelin on the gastric distension (GD) sensitive neurons and gastric motility in the lateral hypothalamic area (LHA), and the possible regulation by the lateral septum. Extracellular single unit discharges were recorded and the gastric motility was monitored by administration of ghrelin into LHA and electrical stimulation of lateral septum. Expression of GHS-R was determined by polymerase chain reaction (PCR), western blot and immunohistochemistry staining. Projection of nerve fiber and expression of ghrelin were observed by retrograde tracer and fluo-immunohistochemistry staining. Results revealed that there were GD neurons in the LHA, and administration of ghrelin could excite both GD-excitatory (GD-E) and GD-inhibited (GD-I) neurons in the LHA. The gastric motility was significantly promoted by administration of ghrelin into LHA with a dose dependent manner, which could be completely abolished by treatment with ghrelin receptor antagonist [D-Lys-3]-GHRP-6 or BIM-28163. c-Fos expression was significantly increased after ghrelin administration to the LHA. Electrical stimulation of the lateral septum could significantly excite GD neurons responsive to ghrelin in the LHA as well as promote gastric motility. However, those effects could be absorbed by pre-treatment of [D-Lys-3]-GHRP-6. GHSR-1a expression in the LHA had no change after ghrelin administration to the LHA or electrical stimulating lateral septum. Electrical lesion of the LHA resulted in the decrease of gastric motility. GHS-R and Ghrelin/FG-double labeled neurons were observed in the LHA and lateral septum, respectively. It is suggested that the LHA may involve in promoting gastric motility via ghrelin. The Lateral septum projects to the LHA and exerts some regulating function on the LHA. PMID:24100167

Gong, Yanling; Xu, Luo; Wang, Hongbo; Guo, Feifei; Sun, Xiangrong; Gao, Shengli

2013-12-01

173

Lateral Mode Control of Semiconductor Lasers  

NASA Astrophysics Data System (ADS)

This thesis deals with several topics related to the lateral modes of edge-emitting semiconductor lasers. The first topic is the improvement of lateral beam quality for high power operation. A thermally controlled antiguiding unstable-resonator semiconductor laser with cleaved facets is proposed. With temperature controlled by monolithically integrated micro-heaters, the beam propagation factor is improved by 8 times at 300 mW and by 6 time at 600 mW. The second issue is monolithic semiconductor laser beam steering. Two new mechanisms, thermally controlled offset gain and index guiding lasers and fan laser arrays, have been proposed and demonstrated. They both have single-lobed Gaussian intensity distributions. The fan laser array has shown a total steering angle of 80^circ with eleven resolvable spots, which surpasses the previous results by a factor of three. The third issue is the nonlinear interaction between the semiconductor gain medium and optical waves. The filamentation effect is studied with perturbation theory. Analytical spatial solitary waves have been obtained. The fourth issue is the complex Hermite-Gaussian functions and their applications. An analytical integral expression has been obtained. The generalized complex Gaussian duct is discussed. It is found that the biorthogonal mode expansion and adjoint mode coupling theory in unstable resonators need to be improved. The fifth issue is the lateral modes of stable resonator and stadium resonator semiconductor lasers which have been designed, fabricated and tested. For the stable cavity semiconductor lasers, three distinct operation regions are identified as the stable cavity region, the transition region, and the geometrically unstable region. Preliminary results on stadium resonator semiconductor lasers have also been obtained.

Sun, Yan

174

Lateral Flagellar Gene System of Vibrio parahaemolyticus  

PubMed Central

Vibrio parahaemolyticus possesses dual flagellar systems adapted for movement under different circumstances. A single polar flagellum propels the bacterium in liquid (i.e., swimming) with a motor that is powered by the sodium motive force. Multiple proton-driven lateral flagella enable translocation over surfaces (i.e., swarming). The polar flagellum is produced continuously, while production of lateral flagella is induced when the organism is grown on surfaces. This work describes the isolation of mutants with insertions in the structural and regulatory laf genes. A Tn5-based lux transcriptional reporter transposon was constructed and used for mutagenesis and subsequent transcriptional analysis of the laf regulon. Twenty-nine independent insertions were distributed within 16 laf genes. DNA sequence analysis identified 38 laf genes in two loci. Among the mutants isolated, 11 contained surface-induced lux fusions. A hierarchy of laf gene expression was established following characterization of the laf::lux transcriptional fusion strains and by mutational and primer extension analyses of the laf regulon. The laf system is like many enteric systems in that it is a proton-driven, peritrichous flagellar system; however, laf regulation was different from the Salmonella-Escherichia coli paradigm. There is no apparent flhDC counterpart that encodes master regulators known to control flagellar biosynthesis and swarming in many enteric bacteria. A potential ?54-dependent regulator, LafK, was demonstrated to control expression of early genes, and a lateral-specific ?28 factor controls late flagellar gene expression. Another notable feature was the discovery of a gene encoding a MotY-like product, which previously had been associated only with the architecture of sodium-type polar flagellar motors.

Stewart, Bonnie J.; McCarter, Linda L.

2003-01-01

175

Lateral tunneling through voltage-controlled barriers  

NASA Technical Reports Server (NTRS)

The paper reports on a detailed experimental investigation of lateral tunneling between electrodes of a two-dimensional electron gas separated by the voltage-controlled barrier of a nanometer Schottky gate. The experimental data are modeled using the WKB method to calculate the tunneling probability of electrons through a barrier whose shape is determined from a solution of the two-dimensional Poisson equation. This model is in excellent agreement with the experimental data over a two order of magnitude range of current.

Manion, S. J.; Bell, L. D.; Kaiser, W. J.; Maker, P. D.; Muller, R. E.

1991-01-01

176

Lateral Interactions in Monolayer Thick Mercury Films  

NASA Astrophysics Data System (ADS)

An understanding of lateral adatom-adatom interactions is often an important part of understanding electronic structure and adsorption energetics in monolayer thick films. In this dissertation I use angle-resolved photoemission and thermal desorption spectroscopies to explore the relationship between the adatom-adatom interaction and other characteristics of the adlayer, such as electronic structure, defects, or coexistent structural phases in the adlayer. Since Hg binds weakly to many substrates, the lateral interactions are often a major contribution to the dynamics of the overlayer. Hg adlayer systems are thus ideal for probing lateral interactions. The electronic structures of Hg adlayers on Ag(100), Cu(100), and Cu_3Au(100) are studied with angle-resolved ultraviolet photoemission. The Hg atomic 5d_{5/2} electronic band is observed to split into two levels following adsorption onto some surfaces. The energetic splitting of the Hg 5d_{5/2} level is found to be directly correlated to the adlayer homogeneous strain energy. The existence of the split off level also depends on the order or disorder of the Hg adlayer. The energetics of Hg adsorption on Cu(100) are probed using thermal desorption spectroscopy. Two different ordered adlayer structures are observed for Hg adsorption on Cu(100) at 200 K. Under some adsorption conditions and over a range of exposures, the two phases are seen to coexist on the surface prior to the thermal desorption process. A phase transition from the more dense to the less dense phase is observed to occur during the thermal desorption process. Inherent differences in defect densities are responsible for the observed differences between lateral interactions measured previously with equilibrium (atom beam scattering) and as measured by the non-equilibrium (thermal desorption) technique reported here. Theoretical and experimental evidence for an indirect through-metal interaction between adatoms is also discussed. Although through-metal interactions may play a role in some adsorption systems, there is little compelling evidence that this effect is significant in many experimental reports where the through metal bond is invoked.

Kime, Yolanda Jan

177

Fracture of the lateral femoral condyle.  

PubMed

The patient was a 25-year-old man who was currently enrolled in a military basic-training program. He was evaluated by a physical therapist in a direct-access capacity for a chief complaint of right knee pain and swelling after his knee buckled and gave way during a training exercise on an obstacle course. The patient was evaluated by the physical therapist 2 days after his injury. Because the patient was unable to bear weight on his right lower extremity or flex his right knee to 90°, the physical therapist ordered radiographs of the right knee, which demonstrated a fracture of the lateral femoral condyle posteriorly. PMID:24289034

Carow, Scott D; Potter, Steven M

2013-12-01

178

Responsiveness-to-Intervention: A Decade Later  

PubMed Central

In this introduction to this special issue, “A Decade Later,” we provide an overview of the accomplishments as well as the persistent questions surrounding RTI. We organize this discussion within 3 categories: assessment, instruction, and policy. Within each of these sections, we also highlight how the articles in the present special issue expand upon the key issues. Developed initially for the early grades (kindergarten through third grade) and primarily in the area of reading, many-although not all-of these issues speak to the expansion of RTI to address a broader set of academic content areas and the full range of grade levels.

Fuchs, Lynn S.; Vaughn, Sharon

2012-01-01

179

Lateral stress evolution in Chromium Sulfide  

NASA Astrophysics Data System (ADS)

In this paper the shock response of CrS, a cermet of potential interest as a matrix material for ballistic applications, has been investigated. Compacts with a Chromium: Sulfur ratio of 1.15:1 were investigated via the plate-impact technique. These experiments allowed the material to be loaded under a one-dimensional state of strain. Embedded manganin stress gauges were employed to monitor the temporal evolution of longitudinal and lateral components of stress. Comparison of these two components has allowed assessment of the variation of material shear strength both with impact pressure/strain-rate and time.

Petel, O. E.; Appleby-Thomas, G. J.; Hameed, A.; Capozzi, A.; Goroshin, S.; Frost, D. L.; Hazell, P. J.

2014-05-01

180

FUS mutations in sporadic amyotrophic lateral sclerosis.  

PubMed

Mutations in the FUS gene have recently been described as a cause of familial amyotrophic lateral sclerosis (ALS), but their role in the pathogenesis of sporadic ALS is unclear. We undertook mutational screening of all coding exons of FUS in 228 sporadic ALS cases, and, as previous reports suggest that exon 15 represents a mutational hotspot, we sequenced this exon in an additional 1295 sporadic cases. Six variants in six different cases were found, indicating that FUS mutations can underlie apparently sporadic ALS, but account for less than 1% of this form of disease. PMID:20138404

Lai, Shiao-Lin; Abramzon, Yevgeniya; Schymick, Jennifer C; Stephan, Dietrich A; Dunckley, Travis; Dillman, Allissa; Cookson, Mark; Calvo, Andrea; Battistini, Stefania; Giannini, Fabio; Caponnetto, Claudia; Mancardi, Giovanni Luigi; Spataro, Rossella; Monsurro, Maria Rosaria; Tedeschi, Gioacchino; Marinou, Kalliopi; Sabatelli, Mario; Conte, Amelia; Mandrioli, Jessica; Sola, Patrizia; Salvi, Fabrizio; Bartolomei, Ilaria; Lombardo, Federica; Mora, Gabriele; Restagno, Gabriella; Chiò, Adriano; Traynor, Bryan J

2011-03-01

181

Correcting lateral chromatic aberrations by image processing  

NASA Astrophysics Data System (ADS)

We have developed an image processing algorithm that reduces lateral chromatic aberration. It has been implemented in Nikon digital single-lens-reflex cameras and application software. We have developed the aberration detection method which analyzes capture images and detect the aberrations of the image without lens information. Moreover, we have developed the aberration correction method optimized for raw images, which are mosaic images with Bayer color filter array. We also have developed the correction method optimized for in-camera processed images, whose color shift structures are distorted by in-camera processing.

Utsugi, Akihiko; Ishiga, Kenichi

2010-07-01

182

Blepharoplasty lateral internal suspension suture: BLISS technique.  

PubMed

The lower blepharoplasty procedure has had numerous surgical variations described and remains a challenge to those performing the operation. Disappointments with the technique revolve around complications such as lateral third scleral show, hollow sunken eyelids, rounding of the eye and overall long-term, tired, drawn appearance of the lower lids. Multiple adjuncts to the blepharoplasty procedure have been described. These vary in their difficulty of execution and associated complications. The concept of internal muscle suspension has been accepted as a successful adjunct by many authors but often the technique chosen has been a complicated one, adding time and complexity to the procedure. PMID:9502846

Widgerow, A D

1998-01-01

183

AXR1 acts after lateral bud formation to inhibit lateral bud growth in Arabidopsis.  

PubMed

The AXR1 gene of Arabidopsis is required for many auxin responses. The highly branched shoot phenotype of mature axr1 mutant plants has been taken as genetic evidence for a role of auxin in the control of shoot branching. We compared the development of lateral shoots in wild-type Columbia and axr1-12 plants. In the wild type, the pattern of lateral shoot development depends on the developmental stage of the plant. During prolonged vegetative growth, axillary shoots arise and develop in a basal-apical sequence. After floral transition, axillary shoots arise rapidly along the primary shoot axis and grow out to form lateral inflorescences in an apical-basal sequence. For both patterns, the axr1 mutation does not affect the timing of axillary meristem formation; however, subsequent lateral shoot development proceeds more rapidly in axr1 plants. The outgrowth of lateral inflorescences from excised cauline nodes of wild-type plants is inhibited by apical auxin. axr1-12 nodes are resistant to this inhibition. These results provide evidence for common control of axillary growth in both patterns, and suggest a role for auxin during the late stages of axillary shoot development following the formation of the axillary bud and several axillary leaf primordia. PMID:10557232

Stirnberg, P; Chatfield, S P; Leyser, H M

1999-11-01

184

Amyotrophic lateral sclerosis: one or multiple causes?  

PubMed Central

The Amyotrophic lateral sclerosis (ALS) is the most common form of motor neuron disease in the adulthood, and it is characterized by rapid and progressive compromise of the upper and lower motor neurons. The majority of the cases of ALS are classified as sporadic and, until now, a specific cause for these cases still is unknown. To present the different hypotheses on the etiology of ALS. It was carried out a search in the databases: Bireme, Scielo and Pubmed, in the period of 1987 to 2011, using the following keywords: Amyotrophic lateral sclerosis, motor neuron disease, etiology, causes and epidemiology and its similar in Portuguese and Spanish. It did not have consensus as regards the etiology of ALS. Researches demonstrates evidences as regards intoxication by heavy metals, environmental and occupational causes, genetic mutations (superoxide dismutase 1), certain viral infections and the accomplishment of vigorous physical activity for the development of the disease. There is still no consensus regarding the involved factors in the etiology of ALS. In this way, new research about these etiologies are necessary, for a better approach of the patients, promoting preventive programs for the disease and improving the quality of life of the patients.

Bastos, Aline Furtado; Orsini, Marco; Machado, Dionis; Mello, Mariana Pimentel; Nader, Sergio; Silva, Julio Guilherme; da Silva Catharino, Antonio M.; de Freitas, Marcos R.G.; Pereira, Alessandra; Pessoa, Luciane Lacerda; Sztajnbok, Flavio R.; Leite, Marco Araujo; Nascimento, Osvaldo J.M.; Bastos, Victor Hugo

2011-01-01

185

Prototype cantilevers for quantitative lateral force microscopy.  

PubMed

Prototype cantilevers are presented that enable quantitative surface force measurements using contact-mode atomic force microscopy (AFM). The "hammerhead" cantilevers facilitate precise optical lever system calibrations for cantilever flexure and torsion, enabling quantifiable adhesion measurements and friction measurements by lateral force microscopy (LFM). Critically, a single hammerhead cantilever of known flexural stiffness and probe length dimension can be used to perform both a system calibration as well as surface force measurements in situ, which greatly increases force measurement precision and accuracy. During LFM calibration mode, a hammerhead cantilever allows an optical lever "torque sensitivity" to be generated for the quantification of LFM friction forces. Precise calibrations were performed on two different AFM instruments, in which torque sensitivity values were specified with sub-percent relative uncertainty. To examine the potential for accurate lateral force measurements using the prototype cantilevers, finite element analysis predicted measurement errors of a few percent or less, which could be reduced via refinement of calibration methodology or cantilever design. The cantilevers are compatible with commercial AFM instrumentation and can be used for other AFM techniques such as contact imaging and dynamic mode measurements. PMID:21974593

Reitsma, Mark G; Gates, Richard S; Friedman, Lawrence H; Cook, Robert F

2011-09-01

186

Lateral epicondylalgia: midlife crisis of a tendon.  

PubMed

The pathogenesis and management of lateral epicondylalgia, or tennis elbow, a common ailment affecting middle-aged subjects of both genders continue to provoke controversy. Currently it is thought to be due to local tendon pathology, pain system changes, and motor system impairment. Its diagnosis is usually clinical, based on a classical history, as well as symptoms and signs. In selected cases, additional imaging (X-rays, ultrasound, and magnetic resonance imaging) can help to confirm the diagnosis. Different treatment modalities have been described, including the use of orthotics, non-steroidal anti-inflammatory drugs, steroid injections, topical glyceryl trinitrate, exercise therapy, manual therapy, ultrasound therapy, laser therapy, extracorporeal shockwave therapy, acupuncture, taping, platelet-rich plasma injections, hyaluronan gel injections, botulinum toxin injections, and surgery. Nevertheless, evidence to select the best treatment is lacking and the choice of therapy depends on the experience of the management team, availability of the equipment and expertise, and patient response. This article provides a snapshot of current medical practice for lateral epicondylalgia management. PMID:24584568

Luk, James K H; Tsang, Raymond C C; Leung, H B

2014-04-01

187

Nappe emplacement under lateral pressure gradient  

NASA Astrophysics Data System (ADS)

New thin viscous approximation is under development specifically targeted to model spontaneous initiation and tens of kilometers horizontal displacement of tectonic nappes. Nappes are few kilometers thing and tens of kilometers long rock units trusted towards foreland often preserving internal lithological consistency and laying at near horizontal position at the end of the emplacement. Significant shear stresses and deviation of principal stresses from vertical is required to explain this very peculiar strain localization style from mechanical point of view. There is also a need for the explanation of their common appearances in most collisional settings. Both pure shear thin sheet and flexural models kinematically eliminate nappes formation. Spreading viscous sheet models, such as used to model glaciers, are also not applicable as the direction of motion is upward, against gravity. The reason for this discrepancy is the hydrostatic pressure approximation of the gravity-driven spreading models. Actually, the thin sheet approximation is not sensitive to the assumptions made on pressure profile. Lateral non-lithostatic pressure gradient-driven viscous sheet model is appropriate for modeling of nappes. In turn, significant non-lithostatic pressure must be supported by flexural rigidity of overlying and underlying units. Lateral gradients of this non-lithostatic pressure are responsible for the significant shear stress and, therefore, deviation of principal stress from vertical.

Podladchikov, Yury; Schmalholz, Stefan

2014-05-01

188

Confronting the Material Convoy in Later Life  

PubMed Central

We adapt a metaphor from life course studies to designate the whole of one’s possessions, across time, as a convoy of material support. This dynamic collection of things supports daily life and the self, but it can also present difficulty in later life. To alleviate the purported burdens of the material convoy, a discourse has arisen that urges elders and their family members to reduce the volume of possessions. An analysis of 11 such possession management texts shows authors addressing two distinct audiences about elders’ need to downsize: family members and elders themselves. Authors who speak to family members do so with an urgent, unsentimental tone that echoes mainstream clutter-control advice about disorderly, overfull households. In texts for elders, the standard critique about consumption and unruly lives is gentler, more sensitive to the meaning of things, and underplays the emotions of divestment. There is stress on the responsibility to spare the next generation and control one’s legacy. These latter texts seem to respect that downsizing in later life symbolizes a narrowing of the life world.

Smith, Gabriella V.; Ekerdt, David J.

2011-01-01

189

Lateral interactions in the outer retina  

PubMed Central

Lateral interactions in the outer retina, particularly negative feedback from horizontal cells to cones and direct feed-forward input from horizontal cells to bipolar cells, play a number of important roles in early visual processing, such as generating center-surround receptive fields that enhance spatial discrimination. These circuits may also contribute to post-receptoral light adaptation and the generation of color opponency. In this review, we examine the contributions of horizontal cell feedback and feed-forward pathways to early visual processing. We begin by reviewing the properties of bipolar cell receptive fields, especially with respect to modulation of the bipolar receptive field surround by the ambient light level and to the contribution of horizontal cells to the surround. We then review evidence for and against three proposed mechanisms for negative feedback from horizontal cells to cones: 1) GABA release by horizontal cells, 2) ephaptic modulation of the cone pedicle membrane potential generated by currents flowing through hemigap junctions in horizontal cell dendrites, and 3) modulation of cone calcium currents (ICa) by changes in synaptic cleft proton levels. We also consider evidence for the presence of direct horizontal cell feed-forward input to bipolar cells and discuss a possible role for GABA at this synapse. We summarize proposed functions of horizontal cell feedback and feed-forward pathways. Finally, we examine the mechanisms and functions of two other forms of lateral interaction in the outer retina: negative feedback from horizontal cells to rods and positive feedback from horizontal cells to cones.

Thoreson, Wallace B.; Mangel, Stuart C.

2012-01-01

190

Lateral force transmission between human tendon fascicles.  

PubMed

Whether adjacent collagen fascicles transmit force in parallel is unknown. The purpose of the present study was to examine the magnitude of lateral force transmission between adjacent collagen fascicles from the human patellar and Achilles tendon. From each sample two adjacent strands of fascicles (phi 300-530 mum) enclosed in a fascicular membrane were dissected. The specimen was deformed to approximately 3% strain in three independent load-displacement cycles in a small-scale tensile testing device. Cycle 1: the fascicles and the fascicular membrane were intact. Cycle 2: one fascicle was transversally cut while the other fascicle and the fascicular membrane were kept intact. Cycle 3: both fascicles were cut in opposite ends while the fascicular membrane was left intact. A decline in peak force of 45% and 55% from cycle 1 to cycle 2, and 93% and 92% from cycle 2 to cycle 3 was observed in the patellar and Achilles tendon fascicles, respectively. A decline in stiffness of 39% and 60% from cycle 1 to cycle 2, and of 93% and 100% from cycle 2 to cycle 3 was observed in the patellar and Achilles tendon fascicles, respectively. The present data demonstrate that lateral force transmission between adjacent collagen fascicles in human tendons is small or negligible, suggesting that tendon fascicles largely act as independent structures and that force transmission principally takes place within the individual fascicles. PMID:17931846

Haraldsson, Bjarki T; Aagaard, Per; Qvortrup, Klaus; Bojsen-Moller, Jens; Krogsgaard, Michael; Koskinen, Satu; Kjaer, Michael; Magnusson, S Peter

2008-03-01

191

Summary of Methods for Calculating Dynamic Lateral Stability and Response and for Estimating Lateral Stability Derivatives  

NASA Technical Reports Server (NTRS)

A summary of methods for making dynamic lateral stability and response calculations and for estimating the aerodynamic stability derivatives required for use in these calculations is presented. The processes of performing calculations of the time histories of lateral motions, of the period and damping of these motions, and of the lateral stability boundaries are presented as a series of simple straightforward steps. Existing methods for estimating the stability derivatives are summarized and, in some cases, simple new empirical formulas are presented. Reference is also made to reports presenting experimental data that should be useful in making estimates of the derivatives. Detailed estimating methods are presented for low-subsonic-speed conditions but only a brief discussion and a list of references are given for transonic- and supersonic-speed conditions.

Campbell, John P; Mckinney, Marion O

1951-01-01

192

Medial patellar subluxation without previous lateral release: a case report.  

PubMed

Medial patellar subluxation (MPS) is normally described following a lateral release. We report on a 14-year-old girl with MPS without previous lateral release. Arthroscopic examination demonstrated MPS at 0 and 30° of flexion, and the patella was tight in flexion on the lateral side. A low lateral release with a tibial tubercle transfer was performed, followed by repair of the lateral release with an iliotibial band flap, and lateral patellofemoral ligament reconstruction. Excellent functional outcome was achieved. This type of patellar instability is often overlooked and a high index of suspicion is needed for appropriate diagnosis and treatment. PMID:24755851

Saper, Michael G; Shneider, David A

2014-07-01

193

Macroscopic lateral heterogeneity observed in a laterally mobile immiscible mixed polyelectrolyte-neutral polymer brush.  

PubMed

We studied mixed poly(ethylene oxide) (PEO) and poly(2-(dimethylamino)ethyl methacrylate) (PDMAEMA) brushes. The question we attempted to answer was: when the chain grafting points are laterally mobile, how will this lateral mobility influence the structure and phase behavior of the mixed brush? Three different model mixed PEO/PDMAEMA brush systems were prepared: (1) a laterally mobile mixed brush by spreading onto the air-water interface a mixture of poly(ethylene oxide)-poly(n-butyl acrylate) (PEO-PnBA) and poly(2-(dimethylamino)ethyl methacrylate)-poly(n-butyl acrylate) (PDMAEMA-PnBA) diblock copolymers (the specific diblock copolymers used will be denoted as PEO113-PnBA100 and PDMAEMA118-PnBA100, where the subscripts refer to the number-average degrees of polymerization of the individual blocks), (2) a mobility-restricted (inseparable) version of the above mixed brush prepared using a PEO-PnBA-PDMAEMA triblock copolymer (denoted as PEO113-PnBA89-PDMAEMA120) having respective brush molecular weights matched with those of the diblock copolymers, and (3) a different laterally mobile mixed PEO and PDMAEMA brush prepared from a PEO113-PnBA100 and PDMAEMA200-PnBA103 diblock copolymer combination, which represents a further more height-mismatched mixed brush situation than described in (1). These three mixed brush systems were investigated by surface pressure-area isotherm and X-ray (XR) reflectivity measurements. These experimental data were analyzed within the theoretical framework of a continuum self-consistent field (SCF) polymer brush model. The combined experimental and theoretical results suggest that the mobile mixed brush derived using the PEO113-PnBA100 and PDMAEMA118-PnBA100 combination (i.e., mixed brush System #1) undergoes a lateral macroscopic phase separation at high chain grafting densities, whereas the more height-mismatched system (System #3) is only microscopically phase separated under comparable brush density conditions even though the lateral mobility of the grafted chains is unrestricted. The macroscopic phase separation observed in the laterally mobile mixed brush system is in contrast with the microphase separation behavior commonly observed in two-dimensional laterally mobile charged small molecule mixtures. Further study is needed to determine the detailed morphologies of the macro- and microphase-separated mixed PEO/PDMAEMA brushes. PMID:24695635

Lee, Hoyoung; Tsouris, Vasilios; Lim, Yunho; Mustafa, Rafid; Choi, Je; Choi, Yun Hwa; Park, Hae-Woong; Meron, Mati; Lin, Binhua; Won, You-Yeon

2014-06-01

194

Electrodiagnosis in persons with amyotrophic lateral sclerosis.  

PubMed

Electrophysiology remains an important tool in the evaluation of patients presenting with signs and symptoms of motor neuron disease. The electrodiagnostic study should include peripheral nerve conduction studies and needle electromyography to both exclude treatable disease and gather evidence regarding a diagnosis of amyotrophic lateral sclerosis (ALS). The recent changes in the revised El Escorial criteria, recommended by the Awaji-shima consensus group, have increased the diagnostic significance of fasciculation potentials to equal that of fibrillation and positive sharp-wave potentials in the needle electromyography examination of patients suspected of having ALS. In addition, electrophysiologic evidence is now considered equivalent to clinical signs and symptoms in reaching a diagnostic certainty of ALS. These changes, strategies for the design, and implementation of an effective electrodiagnostic evaluation, in addition to electrophysiologic techniques and their relationship to the evaluation of a patient with ALS, are reviewed and discussed. PMID:23523708

Joyce, Nanette C; Carter, Gregory T

2013-05-01

195

Drift region optimization of lateral RESURF devices  

NASA Astrophysics Data System (ADS)

High-voltage lateral devices commonly uses the RESURF concept to achieve a high breakdown voltage. This however limits the conducting performance in the drift region due to the drift region charge that is determined by the RESURF criteria. This paper shows a method to overcome this limitation without effecting the breakdown voltage. The concept is to create a dual conducting device by introducing two extra layers in the drift region. Using the proposed method shows that the drift region resistance can be reduced with a factor 2 without significant reduction of the breakdown voltage. The substrate used is a CMOS substrate which makes it possible to use this concept in a conventional CMOS process.

Vestling, L.; Olsson, J.; Eklund, K.-H.

2002-08-01

196

Optical fiber head for providing lateral viewing  

DOEpatents

The head of an optical fiber comprising the sensing probe of an optical heterodyne sensing device includes a planar surface that intersects the perpendicular to axial centerline of the fiber at a polishing angle .theta.. The planar surface is coated with a reflective material so that light traveling axially through the fiber is reflected transverse to the fiber's axial centerline, and is emitted laterally through the side of the fiber. Alternatively, the planar surface can be left uncoated. The polishing angle .theta. must be no greater than 39.degree. or must be at least 51.degree.. The emitted light is reflected from adjacent biological tissue, collected by the head, and then processed to provide real-time images of the tissue. The method for forming the planar surface includes shearing the end of the optical fiber and applying the reflective material before removing the buffer that circumscribes the cladding and the core.

Everett, Matthew J. (Livermore, CA) [Livermore, CA; Colston, Billy W. (Livermore, CA) [Livermore, CA; James, Dale L. (Tracy, CA) [Tracy, CA; Brown, Steve (Livermore, CA) [Livermore, CA; Da Silva, Luiz (Danville, CA) [Danville, CA

2002-01-01

197

ALSOD: the Amyotrophic Lateral Sclerosis Online Database.  

PubMed

More than 100 point mutations spanning the 153 amino acid SOD1 sequence have been identified in individuals with ALS. In 1999 the Amyotrophic Lateral Sclerosis Database (ALSOD) was generated to store these mutations along with ALS patient information to facilitate the identification of a correlation between the SOD1 genotype with the ALS phenotype. Here we report our ongoing development and redesign of the ALSOD database and its automated procedures. The significant new features have improved ALSOD, helping link the mutations of the SOD1 gene to the hypothetical three-dimensional protein structural rearrangement, and the resulting ALS phenotype. Additionally, ALSOD now provides a more comprehensive knowledge base for ALS, detailing genetic, proteomic, and bioinformatics information associated with the disease. ALSOD can be accessed at http://alsod.iop.kcl.ac.uk/als/. PMID:18608099

Wroe, Richard; Wai-Ling Butler, Amy; Andersen, Peter M; Powell, John F; Al-Chalabi, Ammar

2008-08-01

198

Genetics of amyotrophic lateral sclerosis: an update  

PubMed Central

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder involving both upper motor neurons (UMN) and lower motor neurons (LMN). Enormous research has been done in the past few decades in unveiling the genetics of ALS, successfully identifying at least fifteen candidate genes associated with familial and sporadic ALS. Numerous studies attempting to define the pathogenesis of ALS have identified several plausible determinants and molecular pathways leading to motor neuron degeneration, which include oxidative stress, glutamate excitotoxicity, apoptosis, abnormal neurofilament function, protein misfolding and subsequent aggregation, impairment of RNA processing, defects in axonal transport, changes in endosomal trafficking, increased inflammation, and mitochondrial dysfunction. This review is to update the recent discoveries in genetics of ALS, which may provide insight information to help us better understanding of the disease neuropathogenesis.

2013-01-01

199

Spinwaves in Laterally Confined Magnetic Structures  

NASA Astrophysics Data System (ADS)

Recent advances in lithograpic patterning techniques have made it possible to produce high-quality arrays of micrometer size magnetic dots and wires, which are considered a prototype of the next generation magnetic memory. This review covers the current understanding of spin-wave excitations in arrays of magnetic dots and wires. Brillouin light scattering spectroscopy as the main tool as well as the current state of theory of laterally confined spinwaves are discussed. The three most important issues are addressed: the modification of dynamic magnetic properties by patterning due to shape anisotropies, the quantization of spinwaves due to their in-plane confinement in dots and wires, and anisotropic magnetic dipolar coupling between magnetic dots.

Demokritov, Sergey O.; Hillebrands, Burkard

200

Amyotrophic lateral sclerosis: update and new developments  

PubMed Central

Amyotrophic lateral sclerosis (ALS) is the most common form of motor neuron disease. It is typically characterized by adult-onset degeneration of the upper and lower motor neurons, and is usually fatal within a few years of onset. A subset of ALS patients has an inherited form of the disease, and a few of the known mutant genes identified in familial cases have also been found in sporadic forms of ALS. Precisely how the diverse ALS-linked gene products dictate the course of the disease, resulting in compromised voluntary muscular ability, is not entirely known. This review addresses the major advances that are being made in our understanding of the molecular mechanisms giving rise to the disease, which may eventually translate into new treatment options.

Pratt, Ashley J; Getzoff, Elizabeth D; Perry, J Jefferson P

2012-01-01

201

Lateral organ boundaries domain transcription factors  

PubMed Central

Over the last two decades, several transcription factor gene families have been identified with some of them characterized in detail for their roles on transcriptional regulation of plant defense responses against pest or pathogen attack. We have recently added another transcription factor gene family to this list through the characterization of the LATERAL ORGAN BOUNDARIES (LOB) DOMAIN (LBD)-CONTAINING PROTEIN20 (LBD20). We showed LBD20 acts as a repressor of a subset of jasmonate mediated defenses and in susceptibility to the root-infecting fungal pathogen Fusarium oxysporum. However, possible roles for other members of this gene family in plant defense are currently unknown. Here we searched publically available microarray expression data and provide an overview of the expression patterns of selected members of the LBD gene family for their response to other fungal pathogens and soil nematodes. Distinct expression patterns of the LBD genes suggest that certain members of this gene family have previously undescribed roles in plant defense.

Thatcher, Louise F.; Kazan, Kemal; Manners, John M.

2012-01-01

202

'Laterally aggregated' polyacrylamide gels for electrophoresis.  

PubMed

A new method is described for producing highly porous polyacrylamide matrices: polymerization in presence of a preformed hydrophilic polymer. If a standard mixture of monomers (e.g., 5%T, 4%C) is polymerized in presence of, e.g., polyethylene glycol (PEG) 10 kDa, lateral chain aggregation occurs, with formation of large pore sizes. In PEG 10 kDa, the transition from a small- to a large-pore gel is clearly apparent at 0.5% PEG addition and reaches a plateau already at 2.5% PEG. Even with shorter PEG fragments (6.2 and 1 kDa) this transition occurs, but with progressively larger amounts of PEG in solution (up to 25% for the 1 kDa species). Other polymers such as hydroxymethyl cellulose (1000 kDa) and polyvinyl-pyrrolidone (360 kDa and 25 kDa) are also able to elicit this phenomenon. It appears that lateral chain aggregation (before the cross-linking event) is induced via intra-chain hydrogen bonding, since urea and temperature strongly inhibit it, whereas tetramethylurea (an agent quenching hydrophobic interactions) does not hamper it. By scanning electron microscope, it is found that the maximum pore size obtained in a 5%T, 4%C gel in presence of 2.5% PEG 10 kDA is of the order of 0.5 micron, whereas the same 5%T, 4%C control gel would have an average pore diameter of 5 nm. Thus, an increment of pore size of about 2 orders of magnitude is obtained: in these new matrices, a 21000 bp DNA fragment exhibits a much greater migration than in a control gel in which the sample is entrapped at the application site. PMID:1459071

Righetti, P G; Caglio, S; Saracchi, M; Quaroni, S

1992-01-01

203

[Lateralization of the epileptic process and psychology].  

PubMed

In a group of 70 patients with a unilateral epileptic process in the temporal limbic structures, localized in the left half of the brain in 38 patients (26 men, 12 women) and in the right half of the brain in 32 patients (17 men, 15 women) the lateralization of motor functions, asymmetry of emotional mimicry, conjugated deviation of the eye bulbs, intellect, memory, psychomotor rate and personality (laterality test of Mat?jcek--Zlab, Wechsler's intellect and memory scale, Benton, Stroop, VAROS, SUPOS, DSF, Washington Psychosocial--Seizure Inventory WPSI was investigated. Patient with a left-sided epileptic process had only insignificantly lower contact with psychiatry (31.6% as compared with 40.6%). Significantly lower contacts with psychiatry were recorded in 35 patients with a predominance of emotional mimicry (while smiling) on the left (25.0% as compared with 47.1%, p less than 0.05) and particularly significantly low in 18 patients with a combination of signs left-sided epileptic process + predominance of emotional mimicry on the left + deviation of the eyeballs on the right (mathematical stimulus) + genotypical righthandedness (16.7% as compared with 42.3%, p less than 0.025). Men with a left-sided epileptic process displayed a significantly greater anxiety, in women this trend was only indicated. Four women with a left-sided epileptic process anticipating regulation of behaviour was typical, for women with a right-sided epileptic process lower autoregulating inhibitions. A left-sided epileptic process had significantly more often a favourable course of epilepsy (in 65.8% as compared with 25.0%, p less than 0.005). In psychological tests, however, the differentiating criteria were much more than the course of the disease invalid pension, contact with psychiatry and subjective need of assistance from a psychiatrist or psychologist. PMID:2731273

Preiss, J; Kristof, M

1989-04-01

204

Cerebral Laterality and Handedness in Aviation: Performance and Selection Implications.  

National Technical Information Service (NTIS)

This paper reviews the general psychology literature related to handedness and cerebral laterality, beginning with a brief discussion of the research methods employed. Aspects of laterality, including vision, audition, tactile perception, spatial ability,...

J. S. Crowley

1989-01-01

205

14 CFR 23.147 - Directional and lateral control.  

Code of Federal Regulations, 2013 CFR

...5) All propeller controls in the position at...the primary lateral control system in any all-engine configuration(s...that the airplane's flight characteristics are...link in the lateral control system would also...

2014-01-01

206

Formation Mechanisms of Europan Ridges with Apparent Lateral Offsets  

Microsoft Academic Search

Evidence for both lateral shearing and orthogonal motion along Europan ridges indicates that apparent lateral offsets are not purely the result of strike-slip motions. We present an analysis of a band and ridge to determine their displacement ratios.

C. E. Bader; S. A. Kattenhorn

2008-01-01

207

Lateralized Interhemispheric Transfer of Color Cues: Evidence for Dynamic Coding Principles of Visual Lateralization in Pigeons  

Microsoft Academic Search

Visual feature discrimination tasks in pigeons reveal a right eye\\/left hemisphere dominance at the population level. Anatomical studies and lesion data show this visual lateralization to be related to asymmetries of the tectofugal system, which ascends from the tectum over the n. rotundus to the forebrain. Anatomically, this system is characterized by numerous morphological and connectional asymmetries which result in

Martina Skiba; Bettina Diekamp; Helmut Prior; Onur Güntürkün

2000-01-01

208

Footballer's Lateral Meniscus: Anterior Horn Tears of the Lateral Meniscus with a Stable Knee.  

PubMed

This paper aimed to identify the characteristics of isolated anterior horn tear of the lateral meniscus in footballers who underwent arthroscopic surgery. We identified 8 patients with stable knee and no ligament injury, who had only isolated anterior horn tear of the lateral meniscus between 2007 and 2009. All 8 patients were footballers, comprising 7 men and 1 woman with mean age of 18.6 years. Arthroscopy revealed multiple longitudinal tears in 2 patients, longitudinal tear in 2 patients, degenerative tear in 3 patients, and flap tear in 1 patient. Two patients were treated by repair, five by partial excision, and one by rasping only. The mean Lysholm score was 65 before surgery and recovered to 89 at the last followup, on average 12 months after surgery. Anterior horn tear of the lateral meniscus in footballers with a stable knee is characterized by pain at the anterolateral aspect of the knee during knee extension, especially when kicking a ball, and pain during weight-bearing knee extension, together with MRI finding of hyperintense signal in the anterior horn of the lateral meniscus. Preoperative diagnosis may be possible based on these findings in footballers. PMID:22084745

Hagino, Tetsuo; Ochiai, Satoshi; Sato, Eiichi; Watanabe, Yoshiyuki; Senga, Shinya

2011-01-01

209

Lateral performance of piles evaluated via inclinometer data  

Microsoft Academic Search

The performance of laterally loaded piles is often obtained via in situ lateral pile–load tests. In general, inclinometer measurement is routinely used in these lateral pile–load tests. In an effort to develop an efficient method for interpretation of lateral pile–load test results via measured inclinometer data only, an analytical model is proposed based on the energy conservation of the pile–soil

San-Shyan Lin; Jen-Cheng Liao; J. T. Chen; Li Chen

2005-01-01

210

Performance of Laterally Loaded Drilled Sockets Founded in Weathered Quartzite.  

National Technical Information Service (NTIS)

The design of drilled shafts for lateral loading poses one of the greatest uncertainties for design engineers. The magnitude of the reaction of the soil or rock surrounding a laterally loaded drilled shaft is a function of the lateral deflection of the sh...

D. A. Brown K. J. Kahle

2002-01-01

211

Lateral Load Test of a Drilled Shaft in Clay.  

National Technical Information Service (NTIS)

The behavior of a laterally drilled shaft in clay has been investigated by conducting a lateral load test on an instrumented shaft. Lateral deflection, shaft rotation, and soil resistance were measured for each applied load. Dial gages were used to measur...

V. R. Kasch H. M. Coyle R. E. Bartoskewitz W. G. Sarver

1977-01-01

212

Fundamental Analysis of Lateral Displacement Estimation Quality in Ultrasound Elastography  

Microsoft Academic Search

Complementary to axial, lateral displacement and strain can provide important information on the biological soft tissues in all applications of elastography. In this paper, the effect of key parameters on the lateral displacement estimation was investigated, in simulations and phantom experiments. The performance of the lateral estimator was evaluated by measuring its associated bias, jitter and correlation coefficient of radio-frequency

Jianwen Luo; Elisa E. Konofagou

2009-01-01

213

Numerical Modeling for Laterally Loaded Piles on a Sloping Ground  

Microsoft Academic Search

Pile foundations are slender structural elements used to transfer loads from structures into deep hard strata below the ground level. It should withstand various types of loads including axial and lateral loads. Normally piles are provided to withstand vertical loads situated in horizontal ground with or without lateral loads. The load transfer mechanism for a laterally loaded pile is very

N. Almas Begum

214

14 CFR 25.147 - Directional and lateral control.  

Code of Federal Regulations, 2012 CFR

...AIRPLANES Flight Controllability...and lateral control. (a...operative engine and to...Lateral control; general...inoperative engine, from steady flight at a speed...Lateral control; airplanes...four or more engines. Airplanes...from steady flight at a...

2014-01-01

215

Predicting Later-Life Outcomes of Early-Life Exposures  

EPA Science Inventory

Background: In utero exposure of the fetus to a stressor can lead to disease in later life. Epigenetic mechanisms are likely mediators of later-life expression of early-life events.Objectives: We examined the current state of understanding of later-life diseases resulting from ea...

216

The Lateral Dynamical Analysis of the Magnetic Levitation System  

Microsoft Academic Search

The lateral dynamic character of the maglev system is investigated by constructing the model of it with the lateral tie. To analyze the relationship between vertical stability and lateral displacement of the electromagnet, the dynamic model is linearized at the equilibrium. Runge-Kutta numerical method is employed to obtain the numerical solution of the differential equations. The boundary curves are drawn,

Hongpo Wang; Jie Li; Kun Zhang

2007-01-01

217

Evaluation of Importance of Lateral Acceleration Derivatives in Extraction of Lateral-Directional Derivatives at High Angles of Attack.  

National Technical Information Service (NTIS)

A theoretical investigation was conducted to determine the importance of the lateral acceleration (beta) derivatives in the extraction of lateral-directional stability derivatives for swept wing airplanes at high angles of attack. Representative values of...

L. T. Nguyen

1974-01-01

218

Bilateral osteochondritis dissecans of the lateral femoral condyle following bilateral total removal of lateral discoid meniscus: a case report.  

PubMed

Osteochondritis dissecans (OCD) of the lateral femoral condyle sometimes occurs with a discoid lateral meniscus. Recently, it was reported that OCD of the lateral femoral condyle occurred after total removal of the lateral meniscus. We report the case of a 12-year-old boy with bilateral OCD of the lateral femoral condyle following bilateral total removal for discoid lateral meniscus. Valgus deviation of the knee after total removal and increased sporting activity might have concentrated excessive stress on the lateral condyles in the standing position. As a result, bilateral OCD might have occurred. Drilling of the areas of OCD on the bilateral lateral femoral condyles was done and the patient wore inner wedge arch supports postoperatively. After 2 years, neither knee pain nor arthrosis has occurred so far, but long-term follow-up of this patient is considered to be necessary. PMID:17985146

Hashimoto, Yusuke; Yoshida, Gen; Tomihara, Tomohiro; Matsuura, Takeshi; Satake, Shinji; Kaneda, Kunikazu; Shimada, Nagakazu

2008-11-01

219

Penetration and lateral diffusion characteristics of polycrystalline graphene barriers.  

PubMed

We report penetration and lateral diffusion behavior of environmental molecules on synthesized polycrystalline graphene. Penetration occurs through graphene grain boundaries resulting in local oxidation. However, when the penetrated molecules diffuse laterally, the oxidation region will expand. Therefore, we measured the lateral diffusion rate along the graphene-copper interface for the first time by the environment-assisted crack growth test. It is clearly shown that the lateral diffusion is suppressed due to the high van der Waals interaction. Finally, we employed bilayer graphene for a perfect diffusion barrier facilitated by decreased defect density and increased lateral diffusion path. PMID:24213805

Yoon, Taeshik; Mun, Jeong Hun; Cho, Byung Jin; Kim, Taek-Soo

2014-01-01

220

Bloch oscillations in lateral periodic nanostructure arrays  

NASA Astrophysics Data System (ADS)

In a periodic structure of electron potential, under an external electric field E, if an electron can reach the boundary of the Brillouin zone (BZ) without being scattered, it undergoes Bragg reflection, passing back into the BZ on the opposite side. This results in a high frequency oscillation of electrons, i.e., Bloch oscillation (BO). Recently, BO has gained a renewed interest, as a Bloch^ oscillator can be utilized as a frequency-tunable THz source. Work on BO has mainly been carried out in quantum well superlattices. On the other hand, a surface superlattices patterned into a two dimensional electron system has long been proposed as an alternative structure to generate BO. Here, we report our experimental results on the negative differential conductance and Bloch oscillation induced edge magnetoplasma resonance in a series of lateral superlattices. Results from the so-called reversed Bloch oscillations measurements and bolometric measurements will also be presented and discussed. Sandia is a multiprogram laboratory operated by Sandia Corporation, a Lockheed Martin company, for the US Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL85000. The facilities of the NSF-sponsored NNIN node at UNM were used for the fabrication.

Pan, W.; Lyo, S. K.; Reno, J. L.; Simmons, J. A.; Li, D.; Brueck, S. R. J.

2009-03-01

221

Aeroservoelastic tailoring for lateral control enhancement  

NASA Technical Reports Server (NTRS)

The need for effective aileron power for aircraft lateral control and turning maneuvers dates back to the Wright Brothers and their wing warping concept for active stabilization of their aircraft. Early researchers in Great Britain, Japan, Germany and the United States explored ways to increase the effectiveness of control aileron to generate a roll moment. The basic problem of aileron effectiveness and the interrelationship between structural distortion and the loads applied by the control surface is illustrated. A rigid wing/aileron surface will develop the capability to generate increased roll rates as airspeed increases. A flexible surface will become less effective as airspeed increases because of the twisting distortion created by the aft-mounted control surface. This tendency is further worsened by bending distortion of an aft swept wing. This study focuses its attention on the ability of a combined effort between structural redesign of a wing and sizing and placement of a control surface to create specified roll performance with a minimum hinge moment. This design optimization problem indicates the advantages of simultaneous consideration of structural design and control design.

Weisshaar, Terrence A.; Changho, Nam

1989-01-01

222

[Laterality of musical functions in partial epilepsy].  

PubMed

Fourteen right handed patients with partial epilepsy (Epileptic Group) and with a median age of 31 years were divided into two groups (Right and Left), according the laterality of paroxystic activity in the electroencaphalogram. Of the 14 patients, 42.8% (6/14) presented a focus at the right side while the others 57.2% (8/14) presented a focus at the left. The Control Group consisted of 31 right handed individuals with a median age of 30 years and with no previous history of neurological disease or epileptic seizures. All the individuals had no musical skills. They carried out Music Abilities Tests including Spontaneous Rhythm, Elemental Music Functions Perception (tone color, duration, pitch, intensity and rhythm) and Complex Strutures Tests (recognition and reproduction of corporal rhythmic movements). We concluded that the focus at the right and the left cerebral hemisphere affect the development of the melodic recognition functions while in cases with focus at the left cerebral hemisphere, rhythmic reproduction and organization are more impaired when compared to the Control Group. PMID:10029877

Correia, C M; Muszkat, M; De Vicenzo, N S; De Campos, C J

1998-12-01

223

Implicit Recognition Based on Lateralized Perceptual Fluency  

PubMed Central

In some circumstances, accurate recognition of repeated images in an explicit memory test is driven by implicit memory. We propose that this “implicit recognition” results from perceptual fluency that influences responding without awareness of memory retrieval. Here we examined whether recognition would vary if images appeared in the same or different visual hemifield during learning and testing. Kaleidoscope images were briefly presented left or right of fixation during divided-attention encoding. Presentation in the same visual hemifield at test produced higher recognition accuracy than presentation in the opposite visual hemifield, but only for guess responses. These correct guesses likely reflect a contribution from implicit recognition, given that when the stimulated visual hemifield was the same at study and test, recognition accuracy was higher for guess responses than for responses with any level of confidence. The dramatic difference in guessing accuracy as a function of lateralized perceptual overlap between study and test suggests that implicit recognition arises from memory storage in visual cortical networks that mediate repetition-induced fluency increments.

Vargas, Iliana M.; Voss, Joel L.; Paller, Ken A.

2012-01-01

224

Field-effect-tuned lateral organic diodes  

PubMed Central

The operation of organic diodes in solar cells and light-emitting displays strongly depends on the properties of the interfaces between hole- and electron-carrying organic semiconductors. Such interfaces are difficult to characterize, as they are usually buried under the surface or exist as an irregular “bulk heterojunction.” Using a unique fluorinated barrier layer-based lithographic technique, we fabricated a lateral organic p-n junction, allowing the first observation of the potential at an organic p-n interface simultaneously with the charge transport measurements. We find that the diode characteristics of the device (current output and rectification ratio) are consistent with the changes in the surface potentials near the junction, and the current-voltage curves and junction potentials are strongly and self-consistently modulated by a third, gate electrode. The generality of our technique makes this an attractive method to investigate the physics of organic semiconductor junctions. The lithographic technique is applicable to a wide variety of soft material patterns. The observation of built-in potentials makes an important connection between organic junctions and textbook descriptions of inorganic devices. Finally, these kinds of potentials may prove to be controlling factors in charge separation efficiency in organic photovoltaics.

Dhar, Bal Mukund; Kini, Geetha S.; Xia, Guoqiang; Jung, Byung Jun; Markovic, Nina; Katz, Howard E.

2010-01-01

225

Amyotrophic lateral sclerosis: Lou Gehrig's disease.  

PubMed

Amyotrophic lateral sclerosis (ALS), commonly called Lou Gehrig's disease, is a progressive neuromuscular condition characterized by weakness, muscle wasting, fasciculations and increased reflexes. Approximately 30,000 Americans currently have the disease. The annual incidence rate is one to two cases per 100,000. The disease is most commonly diagnosed in middle age and affects more men than women. It usually presents with problems in dexterity or gait resulting from muscle weakness. Difficulty in speaking or swallowing is the initial symptom in the bulbar form of the disease. Over a period of months or years, patients with ALS develop severe, progressive muscular weakness and other symptoms caused by loss of function in both upper and lower motor neurons. Sphincter control, sensory function, intellectual abilities and skin integrity are preserved. Patients become completely disabled, often requiring ventilatory support and gastrostomy. Death usually occurs within five years of diagnosis and is attributed to respiratory failure or cachexia. The etiology of the disease is unknown. Current research is focused on abnormalities of neuronal cell metabolism involving glutamate and the role of potential neurotoxins and neurotrophic factors. New drugs are being developed based on these theories. Current management involves aggressive, individualized alleviation of symptoms and complications. PMID:10193591

Walling, A D

1999-03-15

226

Altered cortical communication in amyotrophic lateral sclerosis.  

PubMed

Amyotrophic lateral sclerosis (ALS) is a disorder associated primarily with the degeneration of the motor system. More recently, functional connectivity studies have demonstrated potentially adaptive changes in ALS brain organization, but disease-related changes in cortical communication remain unknown. We recruited individuals with ALS and age-matched controls to operate a brain-computer interface while electroencephalography was recorded over three sessions. Using normalized symbolic transfer entropy, we measured directed functional connectivity from frontal to parietal (feedback connectivity) and parietal to frontal (feedforward connectivity) regions. Feedback connectivity was not significantly different between groups, but feedforward connectivity was significantly higher in individuals with ALS. This result was consistent across a broad electroencephalographic spectrum (4-35 Hz), and in theta, alpha and beta frequency bands. Feedback connectivity has been associated with conscious state and was found to be independent of ALS symptom severity in this study, which may have significant implications for the detection of consciousness in individuals with advanced ALS. We suggest that increases in feedforward connectivity represent a compensatory response to the ALS-related loss of input such that sensory stimuli have sufficient strength to cross the threshold necessary for conscious processing in the global neuronal workspace. PMID:23567743

Blain-Moraes, Stefanie; Mashour, George A; Lee, Heonsoo; Huggins, Jane E; Lee, Uncheol

2013-05-24

227

Multiplex lateral flow immunoassay for mycotoxin determination.  

PubMed

A new lateral flow immunoassay (LFA) is proposed for qualitative and/or semiquantitative determination of aflatoxin B1 (AFB1), zearalenone (ZEA), deoxynivalenol (DON), and their analogues (AFs, ZEAs, DONs) in cereal samples. Each of the mycotoxin specific antibody was class specific and there was no cross reactivity to other groups of compounds. The visual limits of detection (vLOD) of the strip were 0.03, 1.6, and 10 ?g/kg for AFB1, ZEA and DON, respectively. The calculated limits of detection (cLOD) were 0.05, 1, and 3 ?g/kg, respectively. Meanwhile the cutoff values were achieved at 1, 50, and 60 ?g/kg for AFB1, ZEA and DON, respectively. Recoveries ranged from 80% to 122% and RSD from 5% to 20%. Both the vLOD and cLOD for the three mycotoxins were lower than the EU maximum levels. Analysis of naturally contaminated maize samples resulted in a good agreement between the multiplex LFA and LC-MS/MS (100% for DONs and AFs, and 81% for ZEAs). Careful analysis of the results further explained the general overestimation of LFA compared to chromatographic methods for quantification of mycotoxins. PMID:24745689

Song, Suquan; Liu, Na; Zhao, Zhiyong; Njumbe Ediage, Emmanuel; Wu, Songling; Sun, Changpo; De Saeger, Sarah; Wu, Aibo

2014-05-20

228

Error minimization in lateral inhibition circuits.  

PubMed

The pattern of the sensory bristles in the fruit fly Drosophila is remarkably reproducible. Each bristle arises from a sensory organ precursor (SOP) cell that is selected, through a lateral inhibition process, from a cluster of proneural cells. Although this process is well characterized, the mechanism ensuring its robustness remains obscure. Using probabilistic modeling, we defined the sources of error in SOP selection and examined how they depend on the underlying molecular circuit. We found that rapid inhibition of the neural differentiation of nonselected cells, coupled with high cell-to-cell variability in the timing of selection, is crucial for accurate SOP selection. Cell-autonomous interactions (cis interactions) between the Notch receptor and its ligands Delta or Serrate facilitate accurate SOP selection by shortening the effective delay between the time when the inhibitory signal is initiated in one cell and the time when it acts on neighboring cells, suggesting that selection relies on competition between cis and trans interactions of Notch with its ligands. The cis interaction model predicts that the increase in ectopic SOP selections observed with reduced Notch abundance can be compensated for by reducing the abundance of the Notch ligands Delta and Serrate. We validated this prediction experimentally by quantifying the frequency of ectopic bristles in flies carrying heterozygous null mutations of Notch, Delta, or Serrate or combinations of these alleles. We propose that susceptibility to errors distinguishes seemingly equivalent designs of developmental circuits regulating pattern formation. PMID:20606215

Barad, Omer; Rosin, Dalia; Hornstein, Eran; Barkai, Naama

2010-01-01

229

Pemberton's Sign: Explained Nearly 70 Years Later.  

PubMed

Context: Pemberton's sign is used to evaluate venous obstruction in patients with goiters. The sign is positive when bilateral arm elevation causes facial plethora. It has been attributed to a "cork effect" resulting from the thyroid obstructing the thoracic inlet, thereby increasing pressure on the venous system. According to some, the "cork effect" is caused by the thyroid descending into the thoracic inlet during arm elevation. According to others, the obstruction is due to elevation of the thoracic inlet against the thyroid. Objective: We studied a 36-year-old man with a positive Pemberton's sign secondary to a goiter extending to the substernal region. Design and Intervention: Clinical, biochemical, and radiological assessments were done. Magnetic resonance angiography of the neck was performed while the patient's arms were elevated and at his sides. After the imaging studies were completed, the patient underwent thyroidectomy. Results: Magnetic resonance angiography demonstrated that there was no craniocaudal movement of the goiter relative to the thoracic inlet. However, the lateral aspect of the clavicle moved medially and inferiorly, obstructing the right external jugular vein and subclavian vein confluence. Conclusions: In the present case, we demonstrated that when eliciting Pemberton's sign, facial plethora and venous engorgement were due to the clavicles moving and compressing venous vasculature against the enlarged thyroid and not to a "cork effect." Rather, the clavicular motion observed during arm elevation could be compared to the movement of a "nutcracker" compressing major venous structures within a narrowed thoracic inlet against a relatively fixed and enlarged thyroid. PMID:24646105

De Filippis, Elena A; Sabet, Amin; Sun, Maryellen R M; Garber, Jeffrey R

2014-06-01

230

Lateral superior olive function in congenital deafness  

PubMed Central

The development of cochlear ilmplants for the treatment of patients with profound hearing loss has advanced considerably in the last few decades, particularly in the field of speech comprehension. However, attempts to provide not only sound decoding but also spatial hearing are limited by our understanding of circuit adaptations in the absence of auditory input. Here we investigate the lateral superior olive (LSO), a nucleus involved in interaural level difference (ILD) processing in the auditory brainstem using a mouse model of congenital deafness (the dn/dn mouse). An electrophysiological investigation of principal neurons of the LSO from the dn/dn mouse reveals a higher than normal proportion of single spiking (SS) neurons, and an increase in the hyperpolarisation-activated Ih current. However, inhibitory glycinergic input to the LSO appears to develop normally both pre and postsynaptically in dn/dn mice despite the absence of auditory nerve activity. In combination with previous electrophysiological findings from the dn/dn mouse, we also compile a simple Hodgkin and Huxley circuit model in order to investigate possible computational deficits in ILD processing resulting from congenital hearing loss. We find that the predominance of SS neurons in the dn/dn LSO may compensate for upstream modifications and help to maintain a functioning ILD circuit in the dn/dn mouse. This could have clinical repercussions on the development of stimulation paradigms for spatial hearing with cochlear implants.

Couchman, Kiri; Garrett, Andrew; Deardorff, Adam S.; Rattay, Frank; Resatz, Susanne; Fyffe, Robert; Walmsley, Bruce; Leao, Richardson N.

2011-01-01

231

Lateral superior olive function in congenital deafness.  

PubMed

The development of cochlear implants for the treatment of patients with profound hearing loss has advanced considerably in the last few decades, particularly in the field of speech comprehension. However, attempts to provide not only sound decoding but also spatial hearing are limited by our understanding of circuit adaptations in the absence of auditory input. Here we investigate the lateral superior olive (LSO), a nucleus involved in interaural level difference (ILD) processing in the auditory brainstem using a mouse model of congenital deafness (the dn/dn mouse). An electrophysiological investigation of principal neurons of the LSO from the dn/dn mouse reveals a higher than normal proportion of single spiking (SS) neurons, and an increase in the hyperpolarisation-activated I(h) current. However, inhibitory glycinergic input to the LSO appears to develop normally both pre and postsynaptically in dn/dn mice despite the absence of auditory nerve activity. In combination with previous electrophysiological findings from the dn/dn mouse, we also compile a simple Hodgkin and Huxley circuit model in order to investigate possible computational deficits in ILD processing resulting from congenital hearing loss. We find that the predominance of SS neurons in the dn/dn LSO may compensate for upstream modifications and help to maintain a functioning ILD circuit in the dn/dn mouse. This could have clinical repercussions on the development of stimulation paradigms for spatial hearing with cochlear implants. PMID:21276842

Couchman, Kiri; Garrett, Andrew; Deardorff, Adam S; Rattay, Frank; Resatz, Susanne; Fyffe, Robert; Walmsley, Bruce; Leão, Richardson N

2011-07-01

232

Misregulated RNA processing in amyotrophic lateral sclerosis  

PubMed Central

Amyotrophic lateral sclerosis (ALS) research is undergoing an era of unprecedented discoveries with the identification of new genes as major genetic causes of this disease. These discoveries reinforce the genetic, clinical and pathological overlap between ALS and frontotemporal lobar degeneration (FTLD). Common causes of these diseases include mutations in the RNA/DNA-binding proteins, TDP-43 and FUS/TLS and most recently, hexanucleotide expansions in the C9orf72 gene, discoveries that highlight the overlapping pathogenic mechanisms that trigger ALS and FTLD. TDP-43 and FUS/TLS, both of which participate in several steps of RNA processing, are abnormally aggregated and mislocalized in ALS and FTLD, while the expansion in the C9orf72 pre-mRNA strongly suggests sequestration of one or more RNA binding proteins in pathologic RNA foci. Hence, ALS and FTLD converge in pathogenic pathways disrupting the regulation of RNA processing. This article is part of a Special Issue entitled RNA-Binding Proteins.

Polymenidou, Magdalini; Lagier-Tourenne, Clotilde; Hutt, Kasey R.; Bennett, C. Frank; Cleveland, Don W.; Yeo, Gene W.

2013-01-01

233

Laterally graded multilayer double-monochromator.  

SciTech Connect

The authors describe a tunable multilayer monochromator with an adjustable bandpass to be used for reflectivity and grazing incidence diffraction studies on surfaces at energies near 10 keV. Multilayers have a bandpass typically 100 times larger than the Si(111) reflection, and by using multilayers an experimenter can significantly increase data collection rates over those available with a Si monochromator. The transmission through 1 and 2 laterally graded multilayer (LGML) reflections was recorded versus photon energy. The identical LGMLs were comprised of 60 bilayers of W and C on 100 x 25 x 3 mm float glass with a bilayer spacing varying from 35 to 60 {angstrom}. The average gradient was 0.27 {angstrom}/mm along the long dimension. The rms deviation of the data for the bilayer spacing from a linear fit was 0.36 {angstrom}. Data were obtained for a nondispersive ({+-}) double-multilayer arrangement. The relative bandpass width (FWHM) when the two multilayers exposed the same bilayer spacing was measured to be 2.2% with a transmission of 78.7 {+-} 1.6%. This value is consistent with the transmission of 88.9% that they also measured for a single LGML at HASYLAB beamline D4. The bandpass was tunable in the range 1.1% to 2.2%.

Als-Nielsen, J.; Erdmann, J.; Gaarde, P.; Krasnicki, S.; Liu, C.; Macrander, A. T.; Maj, J.; Mancini, D.

1999-09-01

234

Redox Regulation in Amyotrophic Lateral Sclerosis  

PubMed Central

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that results from the death of upper and lower motor neurons. Due to a lack of effective treatment, it is imperative to understand the underlying mechanisms and processes involved in disease progression. Regulations in cellular reduction/oxidation (redox) processes are being increasingly implicated in disease. Here we discuss the possible involvement of redox dysregulation in the pathophysiology of ALS, either as a cause of cellular abnormalities or a consequence. We focus on its possible role in oxidative stress, protein misfolding, glutamate excitotoxicity, lipid peroxidation and cholesterol esterification, mitochondrial dysfunction, impaired axonal transport and neurofilament aggregation, autophagic stress, and endoplasmic reticulum (ER) stress. We also speculate that an ER chaperone protein disulphide isomerase (PDI) could play a key role in this dysregulation. PDI is essential for normal protein folding by oxidation and reduction of disulphide bonds, and hence any disruption to this process may have consequences for motor neurons. Addressing the mechanism underlying redox regulation and dysregulation may therefore help to unravel the molecular mechanism involved in ALS.

Parakh, Sonam; Spencer, Damian M.; Halloran, Mark A.; Soo, Kai Y.; Atkin, Julie D.

2013-01-01

235

Retinoid signaling alterations in amyotrophic lateral sclerosis  

PubMed Central

Amyotrophic lateral sclerosis (ALS) is a fatal neuromuscular disease for which effective therapeutic interventions and an understanding of underlying disease mechanism are lacking. A variety of biochemical pathways are believed to contribute to the pathophysiology of ALS that are common to both sporadic and familial forms of the disease. Evidence from both human and animal studies indicates that expression of retinoid signaling genes is altered in ALS and may contribute to motor neuron loss. Our goals were to examine the expression and distribution of proteins of the retinoid signaling pathway in spinal cord samples from patients with sporadic and familial ALS and to evaluate the role of these proteins in motor neuron cell survival. In sporadic ALS, the cytoplasmic binding protein that facilitates nuclear translocation of retinoic acid, cellular retinoic acid binding protein-II (CRABP-II), was localized to the nucleus and retinoic acid receptor ? (RAR?) was significantly increased in motor neuron nuclei when compared to either familial ALS patients or non-neurologic disease controls. Motor neurons with increased nuclear RAR? were negative for markers of apoptosis. Pre-treatment of primary motor neuron-enriched cultures with a pan-RAR or RAR?-specific agonist decreased motor neuron cell death associated with oxidative injury/stress while a RAR?-specific antagonist enhanced cell death. Our data suggest retinoid signaling is altered in ALS and increased nuclear RAR? occurs in motor neurons of sporadic ALS patients. Activation of RAR? protects motor neurons from oxidative-induced cell death.

Kolarcik, Christi L; Bowser, Robert

2012-01-01

236

CSF markers in amyotrophic lateral sclerosis.  

PubMed

Amyotrophic lateral sclerosis (ALS, 'Lou Gehrig disease') is the most common, progressive, neurodegenerative, motor neuron disease, causing damage to upper and lower motor neurons, leading to paralysis and death within 3-5 years. Majority of ALS cases are sporadic ALS (SALS) and only 5-10 % of cases are familial ALS (FALS). Pathogenesis of ALS is complicated and still unclear, including genetic, glutamate excitotoxicity, oxidative stress, mitochondrial dysfunction, neurofilament accumulation, impaired trophic support, altered glial function, viral infection, immune imbalance and impairment of the blood-brain, blood-spinal cord and blood-cerebrospinal fluid barriers (BBB/BSCB/BCSFB). The CSF analysis is still one of the basic laboratory tools and might reflect pathophysiological alterations in the course of the disease and could provide an insight into disease pathomechanisms. The most important aim of its analysis is evaluation of blood-CSF barrier, which is altered in 46 % of ALS patients. The CSF biomarkers may give insight into ALS pathophysiology and may be useful for early, presymptomatic diagnosis, therapeutic monitoring and the development of new therapeutic strategies. This review summarizes the general concepts of biomarkers in CSF of ALS patients and their potential usefulness in further research. PMID:22555610

Tarasiuk, Joanna; Ku?akowska, Alina; Drozdowski, Wies?aw; Kornhuber, Johannes; Lewczuk, Piotr

2012-07-01

237

Lateral patellofemoral ligament reconstruction using a free gracilis autograft.  

PubMed

Medial patellofemoral instability is a rare, disabling condition that is often associated with the wrong indication for lateral retinacular release or overcorrection with medializing tibial tubercle osteotomy. It is an even less common complication after total knee arthroplasty (TKA). The lateral patellofemoral ligament is an important lateral stabilizer of the patella against medial subluxation or dislocation. Until now, no report in the literature has described lateral patellofemoral ligament reconstruction with a free gracilis tendon autograft. Furthermore, there has not been a single case report of lateral patellofemoral ligament reconstruction after TKA. The authors describe a novel technique for reconstruction of the lateral patellofemoral ligament in a symptomatic medial subluxated patella resulting from TKA and extended lateral release in a 62-year-old patient. The result 1 year postoperatively was deemed successful. Clinically, the patella was stable, with correct tracking, and radiologically the patella was correctly positioned. With a technique similar to that used for the medial patellofemoral ligament, the lateral patellofemoral ligament can be reconstructed with a gracilis tendon autograft to permit stabilization independent of resting scar tissue of the lateral retinaculum. This operation can be performed in a minimally invasive way, without opening the joint, therefore decreasing the risk of joint infection. The authors showed a successful clinical and radiologic outcome 1 year after lateral patellofemoral ligament reconstruction in a patient with medial patellar instability after TKA and lateral release. PMID:24992066

Borbas, Paul; Koch, Peter P; Fucentese, Sandro F

2014-07-01

238

An evaluation of the apical seal produced by lateral and warm lateral condensation techniques.  

PubMed

The apical sealing ability of a standard lateral condensation technique was compared with that of two different warm lateral condensation techniques. Sixty extracted human teeth with single canals were instrumented and randomly placed into three groups. Four additional teeth were used as controls. Each group of 20 teeth was obturated with gutta-percha and sealer using one of the three techniques. After 7 days in India ink, the teeth were cleared and the linear extent of ink penetration was measured with a stereomicroscope. No leakage was evident in the two negative controls whereas complete leakage was present in the two positive control teeth. Statistical analysis of the results showed no significant difference in leakage between the experimental groups. PMID:2074407

Luccy, C T; Weller, R N; Kulild, J C

1990-04-01

239

Incidence of Amyotrophic Lateral Sclerosis in Europe  

PubMed Central

Background Geographical differences in amyotrophic lateral sclerosis (ALS) incidence have been reported in the literature, but comparisons across previous studies are limited by different methods in case ascertainment and by the relatively small size of the studied populations. To address these issues, the authors undertook a pooled-analysis of European population-based ALS registries. Methods All new incident ALS cases in subjects 18 years old and older were identified prospectively in six population-based registries in three European countries (Ireland, United Kingdom, Italy) in the two year period 1998-1999 with a reference population of almost 24 million. Results Based on 1,028 identified incident cases, the crude annual incidence rate of ALS in the general European population was 2.16 per 100,000 person-years; 95% CI 2.0-2.3), with similar incidence rates across all registries. The incidence was higher among men (3.0 per 100,000 person-years; 95% CI = 2.8 to 3.3) than among women (2.4 per 100,000 person-years; 95% CI=2.2 to 2.6). Spinal onset ALS was more common among men compared to women, particularly in the 70-80 year age group. Disease occurrence decreases rapidly after 80 years of age. Conclusions ALS incidence is homogeneous across Europe. Sex differences in incidence may be explained by the higher incidence of spinal onset ALS among males and the age-related disease pattern suggests that ALS occurs within a susceptible group within the population rather than being a disease of aging.

Logroscino, Giancarlo; Traynor, Bryan J.; Hardiman, Orla; Chio, Adriano; Mitchell, Douglas; Swingler, Robert J; Millul, Andrea; Benn, Emma; Beghi, Ettore

2010-01-01

240

Tracing the Geomorphic Signature of Lateral Faulting  

NASA Astrophysics Data System (ADS)

Active strike-slip faults are among the most dangerous geologic features on Earth. Unfortunately, it is challenging to estimate their slip rates, seismic hazard, and evolution over a range of timescales. An under-exploited tool in strike-slip fault characterization is quantitative analysis of the geomorphic response to lateral fault motion to extract tectonic information directly from the landscape. Past geomorphic work of this kind has focused almost exclusively on vertical motion, despite the ubiquity of horizontal motion in crustal deformation and mountain building. We seek to address this problem by investigating the landscape response to strike-slip faulting in two ways: 1) examining the geomorphology of the Marlborough Fault System (MFS), a suite of parallel strike-slip faults within the actively deforming South Island of New Zealand, and 2) conducting controlled experiments in strike-slip landscape evolution using the CHILD landscape evolution model. The MFS offers an excellent natural experiment site because fault initiation ages and cumulative displacements decrease from north to south, whereas slip rates increase over four fold across a region underlain by a single bedrock unit (Torlesse Greywacke). Comparison of planform and longitudinal profiles of rivers draining the MFS reveals strong disequilibrium within tributaries that drain to active fault strands, and suggests that river capture related to fault activity may be a regular process in strike-slip fault zones. Simple model experiments support this view. Model calculations that include horizontal motion as well as vertical uplift demonstrate river lengthening and shortening due to stream capture in response to shutter ridges sliding in front of stream outlets. These results suggest that systematic variability in fluvial knickpoint location, drainage area, and incision rates along different faults or fault segments may be expected in catchments upstream of strike-slip faults and could act as useful indicators of fault activity.

Duvall, A. R.; Tucker, G. E.

2012-12-01

241

The AASM Scoring Manual Four Years Later  

PubMed Central

Purpose of Review: Review published studies and critiques which evaluate the impact and effects of the American Academy of Sleep Medicine (AASM) Sleep Scoring Manual in the four years since its publication. Findings: Using the AASM Manual rules to score sleep and events in a polysomnogram (PSG) results in: (1) very large differences in apnea-hypopnea indexes (AHI) when using the recommended and alternative rule for scoring hypopneas in adults; (2) increases in NREM 1 and sleep stage shifts with compensatory decreases in NREM 2 in children and adults when following rule 5.C.b. for ending NREM 2 sleep; (3) increases in NREM 3 in adults scoring slow wave activity in the frontal EEG derivations; (4) improved interscorer reliability; and (5) successfully identified fragmented sleep in children with obstructive sleep apnea (OSA) from primary snorers or normal controls because they had more NREM 1 and stage shifts using rule 5.C.b. Criticism of the Manual most often cited: (1) two rules for scoring hypopneas; (2) alternative EEG montage cancellation effects; (3) scoring stages 3 and 4 as NREM 3; and (4) too few rules for scoring arousals and REM sleep without atonia. Summary: Four years have passed since the AASM Scoring Manual was published with far less criticism than those who developed it feared. The AASM Manual provides a foundation upon which we all can build rules and methods which identify the complexity of sleep and its disorders. Citation: Grigg-Damberger MM. The AASM Scoring Manual four years later. J Clin Sleep Med 2012;8(3):323-332.

Grigg-Damberger, Madeleine M.

2012-01-01

242

PESTICIDE EXPOSURE AND AMYOTROPHIC LATERAL SCLEROSIS  

PubMed Central

Our objectives were to summarize literature on the association of amyotrophic lateral sclerosis (ALS) with pesticides as a group and to evaluate associations of ALS with specific pesticides. We conducted a meta-analysis of published studies of ALS and pesticides as a group and investigated the association of ALS with specific pesticides, using data from the Agricultural Health Study (AHS), a cohort including 84,739 private pesticide applicators and spouses. AHS participants provided information on pesticide use at enrollment in 1993-1997. In mortality data collected through February, 2010, ALS was recorded on death certificates of 41 individuals whom we compared to the remaining cohort (controls), using unconditional logistic regression adjusted for age and gender to calculate odds ratios (ORs) and 95% confidence intervals. In the meta-analysis, ALS was associated with use of pesticides as a group (1.9, 1.1-3.1). In the AHS, ALS was not associated with pesticides as a group, but was associated with use of organochlorine insecticides (OCs) (1.6, 0.8-3.5), pyrethroids (1.4, 0.6-3.4), herbicides (1.6, 0.7-3.7), and fumigants (1.8, 0.8-3.9). ORs were elevated for ever use of the specific OCs aldrin (2.1, 0.8-5.1), dieldrin (2.6, 0.9-7.3), DDT (2.1, 0.9-5.0), and toxaphene (2.0, 0.8-4.9). None of these associations was statistically significant. Similar results were observed in an analysis restricted to men. In conclusion, the meta-analysis suggests that ALS risk is associated with use of pesticides as a group, and our analysis of AHS data points to OC use in particular. The latter results are novel but based on a small number of cases and require replication in other populations.

Kamel, Freya; Umbach, David M; Bedlack, Richard S; Richards, Marie; Watson, Mary; Alavanja, Michael CR; Blair, Aaron; Hoppin, Jane A; Schmidt, Silke; Sandler, Dale P

2012-01-01

243

Pesticide exposure and amyotrophic lateral sclerosis.  

PubMed

Our objectives were to summarize literature on the association of amyotrophic lateral sclerosis (ALS) with pesticides as a group and to evaluate associations of ALS with specific pesticides. We conducted a meta-analysis of published studies of ALS and pesticides as a group and investigated the association of ALS with specific pesticides, using data from the Agricultural Health Study (AHS), a cohort including 84,739 private pesticide applicators and spouses. AHS participants provided information on pesticide use at enrollment in 1993-1997. In mortality data collected through February 2010, ALS was recorded on death certificates of 41 individuals whom we compared to the remaining cohort (controls), using unconditional logistic regression adjusted for age and gender to calculate odds ratios (ORs) and 95% confidence intervals. In the meta-analysis, ALS was associated with use of pesticides as a group (1.9, 1.1-3.1). In the AHS, ALS was not associated with pesticides as a group, but was associated with use of organochlorine insecticides (OCs) (1.6, 0.8-3.5), pyrethroids (1.4, 0.6-3.4), herbicides (1.6, 0.7-3.7), and fumigants (1.8, 0.8-3.9). ORs were elevated forever use of the specific OCs aldrin (2.1, 0.8-5.1), dieldrin (2.6, 0.9-7.3), DDT (2.1, 0.9-5.0), and toxaphene (2.0, 0.8-4.9). None of these associations was statistically significant. Similar results were observed in an analysis restricted to men. In conclusion, the meta-analysis suggests that ALS risk is associated with use of pesticides as a group, and our analysis of AHS data points to OC use in particular. The latter results are novel but based on a small number of cases and require replication in other populations. PMID:22521219

Kamel, Freya; Umbach, David M; Bedlack, Richard S; Richards, Marie; Watson, Mary; Alavanja, Michael C R; Blair, Aaron; Hoppin, Jane A; Schmidt, Silke; Sandler, Dale P

2012-06-01

244

Clinicopathological Characteristics of Laterally Spreading Colorectal Tumor  

PubMed Central

Background and Aims Laterally spreading tumor (LST) is a colorectal pre-cancerous lesion. Previous studies have demonstrated distinct LST clinicopathological characteristics in different populations. This study evaluated clinicopathological characteristics of LST in a Chinese population. Methods A total of 259 Chinese LST patients with 289 lesions were recruited for endoscopic and clinicopathological analyses. Results Among these 289 lesions, 185 were granular type (LST-G), whereas 104 were non-granular type (LST-NG). LST-G lesions were further classified into homogeneous G-type and nodular mixed G-type, while LST-NG lesions were further classified into flat elevated NG-type and pseudo-depressed NG-type. Clinically, these four LST subtypes showed distinct clinicopathological characteristics, e.g., lesion size, location, or histopathological features (high-grade intraepithelial neoplasia and submucosal carcinoma). The nodular mixed G-type showed larger tumor size and higher incidence of high-grade intraepithelial neoplasia compared to the other three subtypes, while pseudo-depressed NG-type lesions showed the highest incidence of submucosal carcinoma. Noticeably, no diffidence was detected between the lesions of homogeneous G-type and flat elevated NG-type with regard to the histopathological features. Histology of the malignancy potential was associated with nodular mixed G-type [OR?=?2.41, 95% CI (1.09–5.29); P?=?0.029], flat elevated NG-type [OR?=?3.49, 95% CI (1.41–8.22); P?=?0.007], Diameter ?30 mm [OR?=?2.56, 95% CI (1.20–5.20); P?=?0.009], Villous adenoma [OR?=?2.76, 95% CI (1.01–7.58); P?=?0.048] and serrated adenoma [OR?=?6.99, 95% CI (1.81–26.98); P?=?0.005]. Conclusion Chinese LSTs can be divided into four different subtypes, which show distinct clinicopathological characteristics. Morphology, size and pathological characteristics are all independent predictors of advanced histology.

Xiang, Li; Wang, Yadong; Wang, Xianfei; Li, Aimin; Liu, Side

2014-01-01

245

Homozygosity analysis in amyotrophic lateral sclerosis  

PubMed Central

Amyotrophic lateral sclerosis (ALS) may appear to be familial or sporadic, with recognized dominant and recessive inheritance in a proportion of cases. Sporadic ALS may be caused by rare homozygous recessive mutations. We studied patients and controls from the UK and a multinational pooled analysis of GWAS data on homozygosity in ALS to determine any potential recessive variant leading to the disease. 620 ALS and 5169 controls were studied in the UK cohort. A total of 7646 homozygosity segments with length >2Mb were identified, and 3568 rare segments remained after filtering “common” segments. The mean total of the autosomal genome with homozygosity segments was longer in ALS than in controls (unfiltered segments, p=0.05). 2017 ALS and 6918 controls were studied in the pooled analysis. There were more regions of homozygosity segments per case (p=1×10?5), a greater proportion of cases harboured homozygosity (p=2×10?5), a longer average length of segment (p=1×10?5), a longer total genome coverage (p=1×10?5), and a higher rate of these segments overlapped with RefSeq gene regions (p=1×10?5), in ALS patients than controls. Positive associations were found in three regions. The most significant was in the chromosome 21 SOD1 region, and also chromosome 1 2.9Mb to 4.8Mb, and chromosome 5 in the 65Mb region. There are more than twenty potential genes in these regions. These findings point to further possible rare recessive genetic causes of ALS which are not identified as common variants in GWAS.

Mok, Kin; Laaksovirta, Hannu; Tienari, Pentti J.; Peuralinna, Terhi; Myllykangas, Liisa; Chio, Adriano; Traynor, Bryan J.; Nalls, Michael A.; Kin Mok, Nicole; Gurunlian, Nicole; Shatunov, Aleksey; Restagno, Gabriella; Mora, Gabriele; Leigh, P Nigel; Shaw, Chris E.; Morrison, Karen E.; Shaw, Pamela J.; Al-Chalabi, Ammar; Hardy, John; Orrell, Richard W.

2013-01-01

246

Determination of lateral-stability derivatives and transfer-function coefficients from frequency-response data for lateral motions  

NASA Technical Reports Server (NTRS)

A method is presented for determining the lateral-stability derivatives, transfer-function coefficients, and the modes for lateral motion from frequency-response data for a rigid aircraft. The method is based on the application of the vector technique to the equations of lateral motion, so that the three equations of lateral motion can be separated into six equations. The method of least squares is then applied to the data for each of these equations to yield the coefficients of the equations of lateral motion from which the lateral-stability derivatives and lateral transfer-function coefficients are computed. Two numerical examples are given to demonstrate the use of the method.

Donegan, James J; Robinson, Samuel W , Jr; Gates, Ordway, B , jr

1955-01-01

247

Unilateral autoscopic phenomena as a lateralizing sign in focal epilepsy.  

PubMed

Positive autoscopic phenomena - autoscopy, heautoscopy and out-of-body experience - may occur in a variety of diseases and also in physiological conditions. They are a rare but probably underreported phenomenon in focal epilepsies. Here, we investigate whether ictal lateralized autoscopic phenomena give lateralizing information about the underlying epileptic focus. We present the cases of seven patients from our center who experienced ictal lateralized autoscopic phenomena and analyzed their focus lateralization and localization of the underlying brain lesion. In addition, we reviewed seven cases published in German and English language literature. In the total group of 14 patients with ictal lateralized autoscopic phenomena, 12 (85.7%) of them had a well-defined epileptic focus contralateral to the side of the autoscopic appearance. Therefore, the data point to an association between ictal lateralized autoscopy and contralateral epileptic focus. PMID:22377330

Hoepner, Robert; Labudda, Kirsten; Hoppe, Matthias; Schoendienst, Martin; Schulz, Reinhard; Tomka-Hoffmeister, Maria; Woermann, Friedrich G; Ebner, Alois; Bien, Christian G; Brandt, Christian

2012-03-01

248

Lateral position detection and control for friction stir systems  

SciTech Connect

Friction stir methods are disclosed for processing at least one workpiece using a rotary tool with rotating member for contacting and processing the workpiece. The methods include oscillating the rotary tool laterally with respect to a selected propagation path for the rotating member with respect to the workpiece to define an oscillation path for the rotating member. The methods further include obtaining force signals or parameters related to the force experienced by the rotary tool at least while the rotating member is disposed at the extremes of the oscillation. The force signals or parameters associated with the extremes can then be analyzed to determine a lateral position of the selected path with respect to a target path and a lateral offset value can be determined based on the lateral position. The lateral distance between the selected path and the target path can be decreased based on the lateral offset value.

Fleming, Paul (Boulder, CO); Lammlein, David H. (Houston, TX); Cook, George E. (Brentwood, TN); Wilkes, Don Mitchell (Nashville, TN); Strauss, Alvin M. (Nashville, TN); Delapp, David R. (Ashland City, TN); Hartman, Daniel A. (Fairhope, AL)

2011-11-08

249

Characterization and deblurring of lateral crosstalk in CMOS image sensors  

Microsoft Academic Search

Lateral crosstalk in CMOS imaging arrays deter effective utilization of small pixel sizes (e.g., < 5.0 ?m × 5.0 ?m) now permitted by technology scaling. A simple measurement setup for empirical characterization of lateral crosstalk in CMOS image sensors is presented. A demonstration of deblurring operations based on the obtained blur model of lateral crosstalk is also provided. Several well-known

Ji Soo Lee; Joey Shah; M. Ed Jernigan; Richard I. Hornsey

2003-01-01

250

The question of symptom lateralization in conversion disorder  

Microsoft Academic Search

Objective: The purpose of this study was to determine whether or not conversion symptoms are lateralized. Studies have shown a predominant left-oriented manifestation of symptoms for most somatoform disorders. The reports in the literature on the lateralization of conversion symptoms, however, are rather conflicting. They show left-sided, right-sided, or no symptom lateralization in conversion disorders. Methods: One hundred fourteen patients

Karin Roelofs; Gérard W. B Näring; Franny C Moene; Cees A. L Hoogduin

2000-01-01

251

Landing adaptations following isolated lateral meniscectomy in athletes  

Microsoft Academic Search

Purpose  Objective functional outcomes following isolated radial lateral meniscus tears in the athlete between the ages of 14–25 are\\u000a not clearly defined. The objective of this study was to determine whether patients following lateral meniscectomy demonstrate\\u000a lower extremity asymmetries relative to control athletes 3 months after surgery. We hypothesized that following lateral meniscectomy,\\u000a athletes aged 14–25 years old would demonstrate altered landing biomechanics

Kevin R. FordStephen; Stephen J. Minning; Gregory D. Myer; Robert E. Mangine; Angelo J. Colosimo; Timothy E. Hewett

252

8. GENERAL VIEW OF LARGE DIVERSION STRUCTURE ON LATERAL WEST ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. GENERAL VIEW OF LARGE DIVERSION STRUCTURE ON LATERAL WEST OF LOWER DERBY LAKE (SECTION 2). - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

253

24. CULVERT WITH CONCRETE HEADWALL AND SIDEWALLS CARRYING THE LATERAL ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

24. CULVERT WITH CONCRETE HEADWALL AND SIDEWALLS CARRYING THE LATERAL UNDER 8TH AVENUE. - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

254

4. SEGMENT OF LATERAL WEST OF C STREET (SECTION 10) ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. SEGMENT OF LATERAL WEST OF C STREET (SECTION 10) ON THE ROCKY MOUNTAIN ARSENAL (RMA). - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

255

2. COURSE OF THE LATERAL THROUGH DEL NORTHWEST MAR PARK. ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. COURSE OF THE LATERAL THROUGH DEL NORTHWEST MAR PARK. - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

256

7. SEGMENT OF LATERAL WITH YUCCA ALONG BANKS, SOUTH OF ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. SEGMENT OF LATERAL WITH YUCCA ALONG BANKS, SOUTH OF 6TH AVENUE (SECTION 10). - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

257

13. TREES ALONG LATERAL SEGMENT AT THE NORTHERN END OF ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

13. TREES ALONG LATERAL SEGMENT AT THE NORTHERN END OF LAKE LADORA. - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

258

Comparison of the obturation of lateral canals by six techniques.  

PubMed

The following obturation techniques were compared on their ability to obturate lateral canals in vitro, lateral condensation (LC), continuous wave of condensation (CW), warm vertical condensation (WV), carrier-based thermoplasticized gutta-percha (CB), warm lateral condensation (WL), and vertically condensed high-temperature gutta-percha (HT). A root canal system with lateral canals in the coronal, middle, and apical thirds was prepared in resin blocks. Each block was obturated using each technique (n = 30, 15 each, with and without sealer). The length of gutta-percha and sealer in each of the lateral canals was measured with a measuring microscope and statistically compared. All techniques obturated all three levels of lateral canals with sealer. WV, CB, and CW were able to fill the lateral canals with gutta-percha significantly better when root canal sealer was used. WV, CB, CW, and HT filled the coronal and middle lateral canals significantly better with gutta-percha than LC or WL condensation. CB and CW filled the apical lateral canal significantly better with gutta-percha than HT, WV, WL, or LC. PMID:10530265

DuLac, K A; Nielsen, C J; Tomazic, T J; Ferrillo, P J; Hatton, J F

1999-05-01

259

23. VIEW SHOWING SALT RIVER PROJECT CREWS SLIPFORMING LATERAL DURING ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

23. VIEW SHOWING SALT RIVER PROJECT CREWS SLIPFORMING LATERAL DURING REHABILITATION AND BETTERMENT PROGRAM Photographer: unknown. April 1968 - Arizona Canal, North of Salt River, Phoenix, Maricopa County, AZ

260

Shoreham Railroad Bridge, Former Addison County Railroad (later, Rutland Railroad, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Shoreham Railroad Bridge, Former Addison County Railroad (later, Rutland Railroad, Addison Branch), spanning Lemon Fair River above Richville Pond, west of East Shoreham Road, Shoreham, Addison County, VT

261

Laterality and emotions: visual laterality in the domestic horse (Equus caballus) differs with objects' emotional value.  

PubMed

Lateralization of emotions has received great attention in the last decades, both in humans and animals, but little interest has been given to side bias in perceptual processing. Here, we investigated the influence of the emotional valence of stimuli on visual and olfactory explorations by horses, a large mammalian species with two large monocular visual fields and almost complete decussation of optic fibres. We confronted 38 Arab mares to three objects with either a positive, negative or neutral emotional valence (novel object). The results revealed a gradient of exploration of the 3 objects according to their emotional value and a clear asymmetry in visual exploration. When exploring the novel object, mares used preferentially their right eyes, while they showed a slight tendency to use their left eyes for the negative object. No asymmetry was evidenced for the object with the positive valence. A trend for an asymmetry in olfactory investigation was also observed. Our data confirm the role of the left hemisphere in assessing novelty in horses like in many vertebrate species and the possible role of the right hemisphere in processing negative emotional responses. Our findings also suggest the importance of both hemispheres in the processing positive emotions. This study is, to our knowledge, the first to demonstrate clearly that the emotional valence of a stimulus induces a specific visual lateralization pattern. PMID:18455205

De Boyer Des Roches, Alice; Richard-Yris, Marie-Annick; Henry, Séverine; Ezzaouïa, Mohammed; Hausberger, Martine

2008-06-01

262

Statistical analysis of lateral migration of the Rio Grande  

Microsoft Academic Search

The lateral migration rates of alluvial rivers are affected by changes in water and sediment regimes. The Rio Grande downstream from Cochiti Dam exhibits spatial and temporal variability in lateral movement rates documented since 1918. A tremendous database exists that documents planform, bed material size, channel geometry, and water and sediment regimes. A statistical analysis reveals that migration rates primarily

263

Modelling vertical and lateral seed bank movements during mouldboard ploughing  

Microsoft Academic Search

The vertical distribution of weed seeds in the soil is of fundamental importance because seedling emergence depends on seed depth. The lateral displacement of the earth during mouldboard ploughing contributes to the dispersal of the weeds inside the tilled field. In order to model vertical and lateral seed displacements during ploughing, an existing model describing soil particle movements for different

Nathalie Colbach; Jean Roger-Estrade; Bruno Chauvel; Jacques Caneill

2000-01-01

264

LATERAL TURBULENCE INTENSITY AND PLUME MEANDERING DURING STABLE CONDITIONS  

EPA Science Inventory

There is much evidence in the literature for the presence of mesoscale lateral meanders in the stable nighttime boundary layer. These meanders result in relatively high lateral turbulence intensities and diffusion rates when averaged over an hour. Anemometer data from 17 overnigh...

265

The Criminal Histories and Later Offending of Child Pornography Offenders  

Microsoft Academic Search

The likelihood that child pornography offenders will later commit a contact sexual offense is unknown. In the present study, we identified a sample of 201 adult male child pornography offenders using police databases and examined their charges or convictions after the index child pornography offense(s). We also examined their criminal records to identify potential predictors of later offenses: 56% of

Michael C. Seto; Angela W. Eke

2005-01-01

266

Lateralness in women's work: New views on success  

Microsoft Academic Search

Data from a longitudinal study of postbaccalaureate nursing careers are discussed in the context of the motive-to-avoid-success controversy. Two groups of nurses with continuous work histories were intensively studied. While most had experienced upward professional mobility, a significant minority had “lateral” careers, which, though not characterized by advancement, typically provide rewards of intensification. Further, lateral careers only occurred in specialties

Ellen Lewin; Virginia Olesen

1980-01-01

267

Prenatal cocaine produces signs of neurodegeneration in the lateral habenula  

Microsoft Academic Search

The lateral habenula is a nucleus in the dorsal thalamus that innervates midbrain dopaminergic and serotonergic nuclei via projections through its major efferent pathway, the fasciculus retroflexus (FR). It was previously demonstrated that cocaine administered continuously to adult rats over several days produces neurodegeneration in the lateral habenula and FR. Because exposure to cocaine during pregnancy reportedly can cause neurobehavioral

Carol A. Murphy; Leyla Ghazi; Azideh Kokabi; Gaylord Ellison

1999-01-01

268

MRI in amyotrophic lateral sclerosis: hyperintensity of the corticospinal tract.  

PubMed

Amyotrophic lateral sclerosis is the most common form of motor neuron disease. The diagnosis is based on clinical and electromyography criteria. The primary role of imaging in amyotrophic lateral sclerosis is to exclude other causes such as cervical degenerative disk disease, Chiari malformation or multiple sclerosis. Imaging is also helpful in atypical cases of the disease. PMID:17139392

Kriaa, S; Zbidi, M; Hafsa, C; Golli, M; Gannouni, A

2005-01-01

269

Nonlinear Frame Models with Lateral Deformable Interfaces: Formulation and Applications  

Microsoft Academic Search

For many years, civil engineers have considered that piles could only support loads applied in line with their central axis. As a result, piles required to resist lateral forces, were installed at a batter. However, it is now realized that the lateral resistance of vertical pile is considerable. Obviously, interactions between the pile and the surrounding soil should be considered

S. Limkatanyu; E. Spacone; K. Kuntiyawichai

270

Eliminating Lateral Violence in the Ambulatory Setting: One Center's Strategies  

Microsoft Academic Search

Lateral violence (eg, disruptive, disparaging, or uncivil behavior inflicted by one peer on another) creates an unpleasant work environment that can have harmful effects on individual nurses, team members, patients, and the bottom line of the health care organization. Educating nurses about the most common forms of lateral violence and strategies for handling inappropriate behavior can be the first step

Tina J. Dimarino

2011-01-01

271

Early Teaching of Chinese Literacy Skills and Later Literacy Outcomes  

ERIC Educational Resources Information Center

This study followed 88 children in Beijing and Hong Kong for three years to investigate the relationships between the early teaching of literacy skills and later literacy outcomes. The children were administered the Preschool and Primary Chinese Literacy Scale at the age of five years, and three years later. Their parents and teachers reported on…

Li, Hui; Corrie, Loraine F.; Wong, Betty Kit Mei

2008-01-01

272

Infant Child Care Patterns and Later Ratings of Preschool Behaviors.  

ERIC Educational Resources Information Center

This study examined (1) the effects of onset of timing for early nonparental care patterns on later child development, and (2) the effects of length of daily enrollment in care on later cognitive attainment and socioemotional behaviors. Preschool teachers rated 105 middle-class children on the Preschool Behavior Questionnaire (PBQ) and the…

Park, Kyung Ja; Honig, Alice Sterling

273

Normal and Lateral Force Calibration Techniques for AFM Cantilevers  

Microsoft Academic Search

Atomic force microscopy (AFM) is a useful tool, not only for imaging but also for quantification of normal and lateral forces exerted on the AFM tip while interacting with the surface of materials. In order to measure these forces, an accurate determination of the normal and lateral forces exerted on the AFM cantilever is necessary. To date, there is no

Manuel L. B. Palacio; Bharat Bhushan

2010-01-01

274

Sensory systems in sawfishes. 2. The lateral line.  

PubMed

The lateral line system allows elasmobranchs to detect hydrodynamic movements in their close surroundings. We examined the distribution of pit organs and lateral line canals in 4 species of sawfish (Anoxypristis cuspidata, Pristis microdon, P. clavata and P. zijsron). Pit organs could only be located in A. cuspidata, which possesses elongated pits that are lined by dermal denticles. In all 4 pristid species, the lateral line canals are well developed and were separated into regions of pored and non-pored canals. In all species the tubules that extend from pored canals form extensive networks. In A. cuspidata, P. microdon and P. clavata, the lateral line canals on both the dorsal and ventral surfaces of the rostrum possess extensively branched and pored tubules. Based on this morphological observation, we hypothesized that these 3 species do not use their rostrum to search in the substrate for prey as previously assumed. Other batoids that possess lateral line canals adapted to perceive stimuli produced by infaunal prey possess non-pored lateral line canals, which also prevent the intrusion of substrate particles. However, this hypothesis remains to be tested behaviourally in pristids. Lateral line canals located between the mouth and the nostrils are non-pored in all 4 species of sawfish. Thus this region is hypothesized to perceive stimuli caused by direct contact with prey before ingestion. Lateral line canals that contain neuromasts are longest in P. microdon, but canals containing neuromasts along the rostrum are longest in A. cuspidata. PMID:21829005

Wueringer, B E; Peverell, S C; Seymour, J; Squire, L; Collin, S P

2011-01-01

275

Lateral Stability of Ballast - Ballast and Foundation Materials Research Program.  

National Technical Information Service (NTIS)

This report presents the results of the lateral stability study of the Ballast and Foundation Materials Research Program. Full-scale lateral stability tests were conducted with a 2-rail, 3-tie system using slag, crushed limestone, and gravel as ballast. V...

W. W. Hay H. C. Peterson D. E. Plotkin P. T. Bakas

1977-01-01

276

Lateral diffusion of rhodopsin in the photoreceptor membrane  

Microsoft Academic Search

Rhodopsin undergoes rapid lateral diffusion in the disk membranes of isolated frog and mudpuppy rods. The rate of lateral diffusion is consistent with the rapid rotational diffusion of rhodopsin: both indicate the disk membrane is highly fluid with a viscosity of ~1P.

Mu-Ming Poo; Richard A. Cone

1974-01-01

277

GaAs MESFET with lateral non-uniform doping  

NASA Technical Reports Server (NTRS)

An analytical model of the GaAs MESFET with arbitrary non-uniform doping is presented. Numerical results for linear lateral doping profile are given as a special case. Theoretical considerations predict that better device linearity and improved F(T) can be obtained by using linear lateral doping when doping density increases from source to drain.

Wang, Y. C.; Bahrami, M.

1983-01-01

278

Clinical, radiologic, and arthroscopic assessment of discoid lateral meniscus  

Microsoft Academic Search

Purpose: To establish the common clinical and radiologic features of discoid lateral meniscus in a setting where magnetic resonance imaging was not routinely possible because of cost and access. Arthroscopy was used to confirm the diagnosis. Type of Study: Retrospective study of group of patients with discoid lateral meniscus as the diagnosis. Methods: Of 1,643 arthroscopies of the knee performed

P. Sripathi Rao; Sharath K. Rao; Rajesh Paul

2001-01-01

279

Semiconductor alloy nanoribbon lateral heterostructures for high-performance photodetectors.  

PubMed

High-performance visible-light photodetectors are achieved based on single nanoribbon lateral heterostructures composed of two different semiconductor alloys epitaxially grown in the lateral direction. They reveal superior spectral response range, responsivity, Ion /Ioff ratio, and external quantum efficiency, relative to devices based on single composition structures. PMID:24677130

Guo, Pengfei; Hu, Wei; Zhang, Qinglin; Zhuang, Xiujuan; Zhu, Xiaoli; Zhou, Hong; Shan, Zhengping; Xu, Jinyou; Pan, Anlian

2014-05-01

280

Effect of lateral sphincterotomy on internal anal sphincter function  

Microsoft Academic Search

PURPOSE: This study was designed to investigate the effect of lateral sphincterotomy on internal anal sphincter function in patients with chronic anal fssure. METHODS: Using an eight-channel perfusion catheter and computerized data analysis, a prospective manometric study was performed on patients with chronic anal fissure undergoing lateral sphincterotomy (LS). RESULTS: Mean resting pressure (MRP) in patients with anal fissure (85.1

N. Williams; N. A. Scott; M. H. Irving

1995-01-01

281

A Biologically Inspired Spiking Neural Network for Sound Source Lateralization  

Microsoft Academic Search

In this paper, a binaural sound source lateralization spiking neural network (NN) will be presented which is inspired by most recent neurophysiological studies on the role of certain nuclei in the superior olivary complex (SOC) and the inferior colliculus (IC). The binaural sound source lateralization neural network (BiSoLaNN) is a spiking NN based on neural mechanisms, utilizing complex neural models,

Kyriakos Voutsas; Jürgen Adamy

2007-01-01

282

Design and fabrication of artificial lateral line flow sensors  

NASA Astrophysics Data System (ADS)

Underwater flow sensing is important for many robotics and military applications, including underwater robots and vessels. We report the development of micromachined, distributed flow sensors based on a biological inspiration, the fish lateral line sensors. Design and fabrication processes for realizing individual lateral line sensor nodes are discussed in this paper, along with preliminary characterization results.

Fan, Zhifang; Chen, Jack; Zou, Jun; Bullen, David; Liu, Chang; Delcomyn, Fred

2002-09-01

283

Race and Gender Differences in Cognitive Laterality: Implications for Leadership.  

ERIC Educational Resources Information Center

Replicating research completed in 1986, a study determined the relationship among cognitive laterality, gender, and reading comprehension for African-American students, as well as gender differences in cognitive laterality and in reading comprehension. Subjects, 40 African-American males, 41 African-American females, 12 White males, and 17 White…

Wesson, Linda Hampton; Holman, David

284

[Begg mechanics in treatment of congenitally missing lateral incisor].  

PubMed

The maxillary lateral incisors are the most frequently missing teeth after the third molars. The cases with congenitally missing lateral incisors are treated either by orthodontically closing the spaces or by space regaining for prosthetic restorations. Malocclusion is the most effective factor for selecting the treatment method. Besides the characteristics of the malocclusion and interdigitation, the colour, the shape, the size and the position of the canines effect the treatment planning. In particular, Class II Div. 1 and Cl. I anterior crowding cases are the most convenient cases for orthodontically closing the missing lateral spaces. In these cases besides the treatment of the present malocclusion the reshaping of the canines is aimed and these teeth are moved to lateral spaces. In this article the treatment of a Cl. II Div. 1 malocclusion case with congenitally maxillary missing lateral incisor with Begg technique will be presented. The changes and variations of the Begg mechanics applied for this case will be discussed. PMID:2101648

Ci?er, S; Telli, A E

1990-04-01

285

Syndesmosis and lateral ankle sprains in the National Football League.  

PubMed

Syndesmosis sprains in the National Football League (NFL) can be a persistent source of disability, especially compared with lateral ankle injuries. This study evaluated syndesmosis and lateral ankle sprains in NFL players to allow for better identification and management of these injuries. Syndesmosis and lateral ankle sprains from a single NFL team database were reviewed over a 15-year period, and 32 NFL team physicians completed a questionnaire detailing their management approach. A comparative analysis was performed analyzing several variables, including diagnosis, treatment methods, and time lost from sports participation. Thirty-six syndesmosis and 53 lateral ankle sprains occurred in the cohort of NFL players. The injury mechanism typically resulted from direct impact in the syndesmosis and torsion in the lateral ankle sprain group (P=.034). All players were managed nonoperatively. The mean time lost from participation was 15.4 days in the syndesmosis and 6.5 days in the lateral ankle sprain groups (P?.001). National Football League team physicians varied treatment for syndesmosis sprains depending on the category of diastasis but recommended nonoperative management for lateral ankle sprains. Syndesmosis sprains in the NFL can be a source of significant disability compared with lateral ankle sprains. Successful return to play with nonoperative management is frequently achieved for syndesmosis and lateral ankle sprains depending on injury severity. With modern treatment algorithms for syndesmosis sprains, more aggressive nonoperative treatment is advocated. Although the current study shows that syndesmosis injuries require longer rehabilitation periods when compared with lateral ankle sprains, the time lost from participation may not be as prolonged as previously reported. PMID:24200441

Osbahr, Daryl C; Drakos, Mark C; O'Loughlin, Padhraig F; Lyman, Stephen; Barnes, Ronnie P; Kennedy, John G; Warren, Russell F

2013-11-01

286

Combined treatment of a dural arteriovenous malformation of the lateral sinus using transarterial and direct lateral sinus embolisation  

Microsoft Academic Search

An 80-year-old man presented with a dural arteriovenous malformation (DAVM) involving the left lateral sinus. A carotid angiogram showed the lateral sinus to be occluded proximally and distally, with unusual retrograde venous outflow from the residual sinus to the cortical veins, including a dilated vein of Labbé. Single photon emission computed tomography showed reduced left frontal and temporal cerebral blood

K. Kasai; H. Iwasa; N. Yamada; S. Asamoto; T. Abe; S. Nemoto

1996-01-01

287

Epigenesis of behavioural lateralization in humans and other animals  

PubMed Central

Despite several decades of research, the epigenesis of behavioural and brain lateralization is still elusive, although its knowledge is important in understanding developmental plasticity, function and evolution of lateralization, and its relationship with developmental disorders. Over the last decades, it has become clear that behavioural lateralization is not restricted to humans, but a fundamental principle in the organization of behaviour in vertebrates. This has opened the possibility of extending descriptive studies on human lateralization with descriptive and experimental studies on other vertebrate species. In this review, we therefore explore the evidence for the role of genes and environment on behavioural lateralization in humans and other animals. First, we discuss the predominant genetic models for human handedness, and conclude that their explanatory power alone is not sufficient, leaving, together with ambiguous results from adoption studies and selection experiments in animals, ample opportunity for a role of environmental factors. Next, we discuss the potential influence of such factors, including perinatal asymmetrical perception induced by asymmetrical head position or parental care, and social modulation, both in humans and other vertebrates, presenting some evidence from our own work on the domestic chick. We conclude that both perinatal asymmetrical perception and later social modulation are likely candidates in influencing the degree or strength of lateralization in both humans and other vertebrates. However, in most cases unequivocal evidence for this is lacking and we will point out further avenues for research.

Schaafsma, S.M.; Riedstra, B.J.; Pfannkuche, K.A.; Bouma, A.; Groothuis, T.G.G.

2008-01-01

288

The auxin influx carrier LAX3 promotes lateral root emergence.  

PubMed

Lateral roots originate deep within the parental root from a small number of founder cells at the periphery of vascular tissues and must emerge through intervening layers of tissues. We describe how the hormone auxin, which originates from the developing lateral root, acts as a local inductive signal which re-programmes adjacent cells. Auxin induces the expression of a previously uncharacterized auxin influx carrier LAX3 in cortical and epidermal cells directly overlaying new primordia. Increased LAX3 activity reinforces the auxin-dependent induction of a selection of cell-wall-remodelling enzymes, which are likely to promote cell separation in advance of developing lateral root primordia. PMID:18622388

Swarup, Kamal; Benková, Eva; Swarup, Ranjan; Casimiro, Ilda; Péret, Benjamin; Yang, Yaodong; Parry, Geraint; Nielsen, Erik; De Smet, Ive; Vanneste, Steffen; Levesque, Mitch P; Carrier, David; James, Nicholas; Calvo, Vanessa; Ljung, Karin; Kramer, Eric; Roberts, Rebecca; Graham, Neil; Marillonnet, Sylvestre; Patel, Kanu; Jones, Jonathan D G; Taylor, Christopher G; Schachtman, Daniel P; May, Sean; Sandberg, Goran; Benfey, Philip; Friml, Jiri; Kerr, Ian; Beeckman, Tom; Laplaze, Laurent; Bennett, Malcolm J

2008-08-01

289

Arthroscopic Lateral Epicondylitis Release Using the "Bayonet" Technique  

PubMed Central

Most patients diagnosed with lateral epicondylitis respond well to conservative management. For patients who do not respond to nonoperative modalities, surgical treatment represents a viable option for long-term symptomatic relief. The arthroscopic surgical technique described in this article has been consistently used by the senior author for the treatment of recalcitrant lateral epicondylitis for more than 5 years (198 patients) without the occurrence of any major complications and appears to be a safe, reliable, and efficacious surgical intervention for the management of lateral epicondylitis.

Stiefel, Eric C.; Field, Larry D.

2014-01-01

290

Thermodynamic and kinetic control of the lateral Si wire growth  

NASA Astrophysics Data System (ADS)

Reproducible lateral Si wire growth has been realized on the Si (100) surface. In this paper, we present experimental evidence showing the unique role that carbon plays in initiating lateral growth of Si wires on a Si (100) substrate. Once initiated in the presence of ?5 ML of C, lateral growth can be achieved in the range of temperatures, T = 450-650 °C, and further controlled by the interplay of the flux of incoming Si atoms with the size and areal density of Au droplets. Critical thermodynamic and kinetic aspects of the growth are discussed in detail.

Dedyulin, Sergey N.; Goncharova, Lyudmila V.

2014-03-01

291

30. NORTHERN SEGMENT OF THE LATERAL IN THE NORTHWEST QUARTER ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

30. NORTHERN SEGMENT OF THE LATERAL IN THE NORTHWEST QUARTER OF SECTION 25 STRUCTURE PICTURED IN CO-43-A-28. - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

292

11. CONTINUATION OF LATERAL LEAVING THE DIVERSION STRUCTURE WEST OF ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

11. CONTINUATION OF LATERAL LEAVING THE DIVERSION STRUCTURE WEST OF LOWER DERBY LAKE (SECTION 2), SHOWING MEASURING GAUGE. - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

293

1. HEAD GATE OF THE SAND CREEK LATERAL AT THE ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. HEAD GATE OF THE SAND CREEK LATERAL AT THE HIGH LINE CANAL ON THE SOUTH END OF THE PEORIA STREET BRIDGE. - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

294

12. CONCRETE LINING ON A CURVING SEGMENT OF THE LATERAL ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

12. CONCRETE LINING ON A CURVING SEGMENT OF THE LATERAL NEAR THE NORTHEAST END OF LAKE LADORA (SECTION 2). - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

295

Building the posterior lateral line system in zebrafish  

PubMed Central

The posterior lateral line in zebrafish has emerged as an excellent system to study how a sensory organ system develops. Here we review recent studies that illustrate how interactions between multiple signaling pathways coordinate cell fate, morphogenesis and collective migration of cells in the posterior lateral line primordium. These studies also illustrate how the posterior lateral line system is contributing much more broadly to our understanding of mechanisms operating during the growth, regeneration and self-organization of other organ systems during development and disease.

Chitnis, Ajay B; Nogare, Damian Dalle; Matsuda, Miho

2012-01-01

296

Resume and analysis of NACA lateral control research  

NASA Technical Reports Server (NTRS)

An analysis of the principal results of recent lateral control research is made. Two things are considered of primary importance in judging the effectiveness of different control devices: The (calculated) banking and yawing motion of a typical small airplane caused by a deflection of the control, and the stick force required to produce this deflection. The report includes a table in which a number of different lateral control devices are compared on these bases. Test flights demonstrated that satisfactory lateral control at high angles of attack depends as much on the retention of stability as on aileron effectiveness.

Weick, F. E.; Jones, R. T.

1976-01-01

297

31. THE BRICK BUILDING IS THE FACTORY BEFORE LATER ADDITIONS, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

31. THE BRICK BUILDING IS THE FACTORY BEFORE LATER ADDITIONS, LOOKING NORTHWEST. TAKEN CIRCA 1886-90, PHOTOGRAPHER UNKNOWN. - Ybor Cigar Factory, 1916 North Fourteenth Street, Tampa, Hillsborough County, FL

298

Lateral PNP bipolar transistor with aiding field diffusions  

NASA Technical Reports Server (NTRS)

Fabrication technique produces field aided lateral PNP transistors compatible with micropower switching circuits. The sub-collector diffusion is performed with phosphorus as the dopant and the epitaxy is grown using the higher temperature silicon tetrachloride process.

Gallagher, R. C.; Mc Cann, D. H.

1969-01-01

299

Occurrence of Amyotropic Lateral Sclerosis Among Gulf War Veterans.  

National Technical Information Service (NTIS)

Context. A nation wide epidemiological investigation was undertaken in response to Gulf War Veterans' concerns of high rates of amyotrophic lateral sclerosis (ALS). To determine if Gulf War veterans have an elevated rate of ALS.

R. D. Homer K. G. Kamins J. R. Feussner S. C. Grambow J. Hoff-Lindquist

2002-01-01

300

13. VIEW OF LOG BRIDGE (LATER SUPERSEDED BY THE WIREROPE ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

13. VIEW OF LOG BRIDGE (LATER SUPERSEDED BY THE WIRE-ROPE SUSPENSION BRIDGE), SHOWING OVERHANG WHERE ROCK WAS BLASTED OUT, LOOKING NORTHEAST - Goat Trail Mining Road, Highway 20, 1.5 miles North of Newhalem, Newhalem, Whatcom County, WA

301

14. VIEW OF LOG BRIDGE (LATER SUPERSEDED BY THE WIREROPE ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

14. VIEW OF LOG BRIDGE (LATER SUPERSEDED BY THE WIRE-ROPE SUSPENSION BRIDGE), SHOWING OVERHANG WHERE ROCK WAS BLASTED OUT, LOOKING SOUTHWEST - Goat Trail Mining Road, Highway 20, 1.5 miles North of Newhalem, Newhalem, Whatcom County, WA

302

DETAIL OF ORIGINAL DOOR (LOUVERS ADDED LATER) ON THE SOUTH ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

DETAIL OF ORIGINAL DOOR (LOUVERS ADDED LATER) ON THE SOUTH SIDE. VIEW FACING NORTH-NORTHWEST. - U.S. Naval Base, Pearl Harbor, Aviation Storehouse, Vincennes Avenue at Simms Street, Pearl City, Honolulu County, HI

303

8. DETAIL VIEW, LOOKING NORTHEAST, SHOWING OUTRIGGERS FOR LATERAL BRACING ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. DETAIL VIEW, LOOKING NORTHEAST, SHOWING OUTRIGGERS FOR LATERAL BRACING FOR TRUSSES AND BOTTOM CHORD CONNECTIONS. - White Bowstring Arch Truss Bridge, Spanning Yellow Creek at Cemetery Drive (Riverside Drive), Poland, Mahoning County, OH

304

Oligodendrocyte dysfunction in the pathogenesis of amyotrophic lateral sclerosis  

PubMed Central

Oligodendrocytes are well known targets for immune-mediated and infectious diseases, and have been suggested to play a role in neurodegeneration. Here, we report the involvement of oligodendrocytes and their progenitor cells in the ventral grey matter of the spinal cord in amyotrophic lateral sclerosis, a neurodegenerative disease of motor neurons. Degenerative changes in oligodendrocytes were abundantly present in human patients with amyotrophic lateral sclerosis and in an amyotrophic lateral sclerosis mouse model. In the mouse model, morphological changes in grey matter oligodendrocytes became apparent before disease onset, increasingly so during disease progression, and oligodendrocytes ultimately died. This loss was compensated by increased proliferation and differentiation of oligodendrocyte precursor cells. However, these newly differentiated oligodendrocytes were dysfunctional as suggested by their reduced myelin basic protein and monocarboxylate transporter 1 expression. Mutant superoxide dismutase 1 was found to directly affect monocarboxylate transporter 1 protein expression. Our data suggest that oligodendroglial dysfunction may be a contributor to motor neuron degeneration in amyotrophic lateral sclerosis.

Philips, Thomas; Bento-Abreu, Andre; Nonneman, Annelies; Haeck, Wanda; Staats, Kim; Geelen, Veerle; Hersmus, Nicole; Kusters, Benno; Van Den Bosch, Ludo; Van Damme, Philip; Richardson, William D.

2013-01-01

305

29. DECK / WEB / LATERAL BRACING DETAIL OF CANTILEVER ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

29. DECK / WEB / LATERAL BRACING DETAIL OF CANTILEVER ARM OF THROUGH TRUSS. VIEW TO WEST. - MacArthur Bridge, Spanning Mississippi River on Highway 34 between IA & IL, Burlington, Des Moines County, IA

306

45 CFR 2541.510 - Later disallowances and adjustments.  

Code of Federal Regulations, 2013 CFR

...Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS...obligation to return any funds due as a result of later refunds, corrections, or other transactions; (c) Records retention as...

2013-10-01

307

Measurement of Lateral Tire Performance on Winter Surfaces.  

National Technical Information Service (NTIS)

Extending two-dimensional models of tire vehicle interaction to full three-dimensional functionality requires an understanding of lateral forces on off-road terrain and low-friction surfaces. Experiments were conducted at the Nevada Automotive Test Center...

G. Phetteplace S. Shoop T. Slagle

2007-01-01

308

Distant touch hydrodynamic imaging with an artificial lateral line.  

PubMed

Nearly all underwater vehicles and surface ships today use sonar and vision for imaging and navigation. However, sonar and vision systems face various limitations, e.g., sonar blind zones, dark or murky environments, etc. Evolved over millions of years, fish use the lateral line, a distributed linear array of flow sensing organs, for underwater hydrodynamic imaging and information extraction. We demonstrate here a proof-of-concept artificial lateral line system. It enables a distant touch hydrodynamic imaging capability to critically augment sonar and vision systems. We show that the artificial lateral line can successfully perform dipole source localization and hydrodynamic wake detection. The development of the artificial lateral line is aimed at fundamentally enhancing human ability to detect, navigate, and survive in the underwater environment. PMID:17132735

Yang, Yingchen; Chen, Jack; Engel, Jonathan; Pandya, Saunvit; Chen, Nannan; Tucker, Craig; Coombs, Sheryl; Jones, Douglas L; Liu, Chang

2006-12-12

309

C-Section May Raise Odds of Failed Pregnancy Later  

MedlinePLUS

... sharing features on this page, please enable JavaScript. C-Section May Raise Odds of Failed Pregnancy Later: ... release. While the study finds an association between c-sections and failed pregnancies, it does not prove ...

310

20. WEB / DECK / LATERAL BRACING DETAIL OF THROUGH ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

20. WEB / DECK / LATERAL BRACING DETAIL OF THROUGH TRUSSES. VIEW TO WEST. - Abraham Lincoln Memorial Bridge, Spanning Missouri River on Highway 30 between Nebraska & Iowa, Blair, Washington County, NE

311

VIEW OF MORTARED ROCK AND CONCRETE INLET TO COUCH LATERAL ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

VIEW OF MORTARED ROCK AND CONCRETE INLET TO COUCH LATERAL CANAL, UPSTREAM OF COLLINS ROAD. LOOKING NORTH/NORTHEAST - Tumalo Irrigation District, Tumalo Project, West of Deschutes River, Tumalo, Deschutes County, OR

312

ADHD Drugs Linked to Later Weight Gain in Kids  

MedlinePLUS

... ADHD Drugs Linked to Later Weight Gain in Kids Study found 'rebound' effect in children who stopped ... weight differences seem to be most pronounced for kids who had taken stimulant medications to control their ...

313

Diagnostic Assays Including Multiplexed Lateral Flow Immunoassays with Quantum DOTS.  

National Technical Information Service (NTIS)

Multiplexed lateral flow assays, related methods, and devices are disclosed which are capable of simultaneously detecting multiple analytes. The assays are preferably immunoassays and can be multiplexed spatially, spectrally, and both spatially and spectr...

J. L. Lambert A. M. Fisher

2005-01-01

314

13. DETAIL, LATERAL BRACING FOR INTERIOR OVERHEAD CRANE Delaware, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

13. DETAIL, LATERAL BRACING FOR INTERIOR OVERHEAD CRANE - Delaware, Lackawanna & Western Railroad Freight & Rail Yard, Multiple Unit Light Inspection Shed, New Jersey Transit Hoboken Terminal Rail Yard, Hoboken, Hudson County, NJ

315

Lateral blasts at Mount St. Helens and hazard zonation  

USGS Publications Warehouse

Lateral blasts at andesitic and dacitic volcanoes can produce a variety of direct hazards, including ballistic projectiles which can be thrown to distances of at least 10 km and pyroclastic density flows which can travel at high speed to distances of more than 30 km. Indirect effect that may accompany such explosions include wind-borne ash, pyroclastic flows formed by the remobilization of rock debris thrown onto sloping ground, and lahars. Two lateral blasts occurred at a lava dome on the north flank of Mount St. Helens about 1200 years ago; the more energetic of these threw rock debris northeastward across a sector of about 30?? to a distance of at least 10 km. The ballistic debris fell onto an area estimated to be 50 km2, and wind-transported ash and lapilli derived from the lateral-blast cloud fell on an additional lobate area of at least 200 km2. In contrast, the vastly larger lateral blast of May 18, 1980, created a devastating pyroclastic density flow that covered a sector of as much as 180??, reached a maximum distance of 28 km, and within a few minutes directly affected an area of about 550 km2. The May 18 lateral blast resulted from the sudden, landslide-induced depressurization of a dacite cryptodome and the hydrothermal system that surrounded it within the volcano. We propose that lateral-blast hazard assessments for lava domes include an adjoining hazard zone with a radius of at least 10 km. Although a lateral blast can occur on any side of a dome, the sector directly affected by any one blast probably will be less than 180??. Nevertheless, a circular hazard zone centered on the dome is suggested because of the difficulty of predicting the direction of a lateral blast. For the purpose of long-term land-use planning, a hazard assessment for lateral blasts caused by explosions of magma bodies or pressurized hydrothermal systems within a symmetrical volcano could designate a circular potential hazard area with a radius of 35 km centered on the volcano. For short-term hazard assessments, if seismicity and deformation indicate that magma is moving toward the flank of a volcano, it should be recognized that a landslide could lead to the sudden unloading of a magmatic or hydrothermal system and thereby cause a catastrophic lateral blast. A hazard assessment should assume that a lateral blast could directly affect an area at least 180?? wide to a distance of 35 km from the site of the explosion, irrespective of topography. ?? 1986 Springer-Verlag.

Crandell, D. R.; Hoblitt, R. P.

1986-01-01

316

Lateral photodetectors with Ge quantum dots in Si  

Microsoft Academic Search

Lateral photodetectors with semiconductor quantum dots are novel devices using intrinsic properties of quantum dots such as the three dimensional confinement potential for carriers. On the InAs\\/GaAs material system they have proven their potential for highly efficient normal incidence operation. In this paper we present a detailed study of lateral photodetectors using intra-valence band transitions in self-assembled Ge dots. Two

C. Miesner; K. Brunner; G. Abstreiter

2001-01-01

317

Increased Lateral Abutment Resistance from Gravel Backfills of Limited Width  

Microsoft Academic Search

Lateral pile cap tests were performed on a pile cap with three backfills to evaluate the static and dynamic behavior. One backfill consisted of loose silty sand while the other two consisted of dense gravel zones 0.91- and 1.82-m wide between the pile cap and the loose silty sand. The 0.91- and 1.82-m wide dense gravel zones increased the lateral

Kyle M. Rollins; Ku Hyun Kwon

2010-01-01

318

High Speed and Low Energy Lateral BJT-CMOS Inverter  

Microsoft Academic Search

A new operation mode for a partially depleted CMOS inverter on SOI is proposed, and a hybrid lateral BJT-CMOS inverter circuit is designed and simulated. The scheme utilizes the gated lateral npn or pnp BJT inherent of n- or p-channel MOSFETs. Forward current is applied to the base terminal of the channel MOSFETs, with a normal pull-up or pull-down MOSFET

Toshiro Akino

319

Laterally resolved measurements of polycrystalline cesium iodide surfaces  

Microsoft Academic Search

The aim of this work was to establish the correlation between the local chemical composition and morphology of polycrystalline cesium iodide (CsI) and its local quantum efficiency. We used a laterally resolved Electron Spectroscopy for Chemical Analysis (ESCA-300) apparatus and a Scanning Auger Microprobe (SAM) to investigate the lateral inhomogeneity of the CsI surface stoichiometry. The local quantum efficiency (QE)

Petra Rudolf; F. Marchal; R. Sporken; R. Caudano; Tiziana dell’ Orto; J. Almeida; A. Braem; F. Piuz; S. Sgobba; G. Paic; E. Nappi; A. Valentini; P. Sartori; C. Coluzza

1997-01-01

320

Spectral and lateral resolved characterisation of X-ray microbeams  

Microsoft Academic Search

A detailed knowledge of the lateral and spectral flux density profile of X-ray microbeams is essential for micro-X-ray spectrometry. We present a scanning technique for the spectral and lateral resolved characterization of the focal profile of microbeams. As an example, the beam profile of a polycapillary lens in its focal plane is investigated. Furthermore, limitations of the scanning technique are

Birgit Kanngießer; Natalia Kemf; Wolfgang Malzer

2002-01-01

321

Spectral and lateral resolved characterisation of X-ray microbeams  

NASA Astrophysics Data System (ADS)

A detailed knowledge of the lateral and spectral flux density profile of X-ray microbeams is essential for micro-X-ray spectrometry. We present a scanning technique for the spectral and lateral resolved characterization of the focal profile of microbeams. As an example, the beam profile of a polycapillary lens in its focal plane is investigated. Furthermore, limitations of the scanning technique are discussed.

Kanngießer, Birgit; Kemf, Natalia; Malzer, Wolfgang

2002-12-01

322

Large Lateral Photovoltaic Effect in Metal-(Oxide-) Semiconductor Structures  

PubMed Central

The lateral photovoltaic effect (LPE) can be used in position-sensitive detectors to detect very small displacements due to its output of lateral photovoltage changing linearly with light spot position. In this review, we will summarize some of our recent works regarding LPE in metal-semiconductor and metal-oxide-semiconductor structures, and give a theoretical model of LPE in these two structures.

Yu, Chongqi; Wang, Hui

2010-01-01

323

Lateral imbalance detection on a UAV based on multiple models  

Microsoft Academic Search

This paper addresses a multiple-model based lateral imbalance detection methodology for an uninhabited air vehicle (UAV). Two critical imbalance failures are considered that are the failure-induced left aileron stuck and the centre-of-gravity shift along the y-axis. A bank of LTI Kalman filters are designed to detect the above lateral failures and a flight control law based on the model predictive

Sajjad Fekri; Da-Wei Gu; Ian Postlethwaite

2009-01-01

324

Delta-Notch Lateral Inhibition within the Organ of Corti  

NASA Astrophysics Data System (ADS)

Lateral inhibition is described as an emergent property of the Delta-Notch signalling network. Two separate model representations of lateral inhibition are proposed for different purposes. One provides information about bioenergetics while the other has the capability to produce a physical representation. It is proposed that both can be used in further studies of the sensory pathways in the human connectome model of brain function.

Summers, R.; Abdulla, T.; Luff, R.

2013-09-01

325

Effectiveness of pulsed electromagnetic field therapy in lateral epicondylitis  

Microsoft Academic Search

We aimed to investigate the efficacy of pulsed electromagnetic field (PEMF) in lateral epicondylitis comparing the modality\\u000a with sham PEMF and local steroid injection. Sixty patients with lateral epicondylitis were randomly and equally distributed\\u000a into three groups as follows: Group I received PEMF, Group II sham PEMF, and Group III a corticosteroid + anesthetic agent\\u000a injection. Pain levels during rest,

Kaan Uzunca; Murat Birtane; Nurettin Ta?tekin

2007-01-01

326

Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

327

Lateral transpsoas lumbar interbody fusion: outcomes and deformity correction.  

PubMed

The lateral transpsoas approach for interbody fusion is a minimally invasive technique that has been gaining increasing popularity in the management of a variety of spinal degenerative disorders. Recently, there has been increasing utilization of this technique in the management of adult deformity. The authors present a review of the current evidence of using the lateral lumbar transpsoas approach in the correction of adult degenerative scoliosis. PMID:24703453

Dahdaleh, Nader S; Smith, Zachary A; Snyder, Laura A; Graham, Randall B; Fessler, Richard G; Koski, Tyler R

2014-04-01

328

Arthroscopic lateral collagen meniscus implant in a professional soccer player  

Microsoft Academic Search

A case of an arthroscopically implanted lateral Collagen Meniscus Implant in a 24-year-old professional soccer player is reported.\\u000a This meniscal scaffold was able to improve knee function and reduce pain in this symptomatic meniscectomized young athlete\\u000a at 36-month follow-up. This is the first case of an arthroscopic lateral collagen meniscal scaffold implanted in a high-level\\u000a soccer player described in literature.

Stefano Zaffagnini; Giulio Maria Marcheggiani Muccioli; Alberto Grassi; Tommaso Bonanzinga; Giuseppe Filardo; Angello Canales Passalacqua; Maurilio Marcacci

329

Discoid lateral meniscus: diagnosis and results of arthroscopic treatment  

Microsoft Academic Search

We evaluated the results of arthroscopic meniscectomy in patients with discoid lateral menisci of the knee. Discoid lateral menisci were detected in 308 patients, of whom 197 (124 males, 73 females; mean age 34.5 years, range 6-67) were clinically, radiologically, and arthroscopically found to be symptomatic and underwent partial meniscectomy. The average period between injury and operation was 13.2 months

Mehmet Asik; Cengiz Sen; Omer F. Taser; Aziz K. Alturfan; Yunus V. Sozen

2003-01-01

330

Medial and lateral discoid menisci: a case report.  

PubMed

Discoid menisci on both medial and lateral tibial plateau are very rare abnormalities. We report a 44-year-old woman with bilateral medial and lateral discoid menisci. She also had anomalous insertion of discoid medial meniscus to anterior cruciate ligament, and pathologic medial patellar plica on the right knee. Meniscectomies has been performed for her torn discoid menisci with satisfactory result on the latest follow-up. PMID:20731824

Kim, Sung-Jae; Lubis, Andri Mt

2010-01-01

331

Direct Measurement of Lateral Force Using Dual Cantilevers  

PubMed Central

We have constructed an experimental system to measure a piconewton lateral force using dual cantilevers which cross with each other. The resolution of the lateral force is estimated to be 3.3 p ± 0.2 pN, which is comparable to forces due to thermal fluctuation. This experimental apparatus works so easily that it will enable us to determine forces during nano-manipulation and nano-tribological measurements.

Ishikawa, Makoto; Ichikawa, Masaya; Miura, Kouji

2012-01-01

332

Laterality of suckling behaviour in three zebra species.  

PubMed

Although side preference while suckling is an easily characterised lateralised behaviour, few studies have been conducted. We observed laterality in suckling behaviour in three captive zebra species to test two hypotheses: laterality affected by the foal (motor laterality) and laterality affected by the mother. In total we observed 35 foals of Grevy's, plains, and mountain zebra in two zoos and recorded 5128 successful suckling bouts and 9095 unsuccessful suckling attempts. At the population level the only factor affecting side preference of suckling bouts and attempts was the identity of the individual foal. Ten foals showed individual preferences: seven foals preferred suckling from the left side of the mother, three preferred suckling from the right side of the mother. The individual preferences increased with increasing age of the foal. Only one foal was refused more often from the opposite side than the preferred side used for suckling whereas three other foals were refused from the preferred side. Foals that preferred suckling either from left or right side were refused by the mare more often than foals which showed non-preference. Thus lateral preferences in suckling behaviour of zebra foals seem to be in line with the motor laterality hypotheses. PMID:22762148

Pluhá?ek, Jan; Olléová, Michaela; Bartošová, Jitka; Pluhá?ková, Jana; Bartoš, Lud?k

2013-05-01

333

Lateral line diversity among ecologically divergent threespine stickleback populations  

PubMed Central

The lateral line is a mechanoreceptive sensory system that allows fish to sense objects and motion in their local environment. Variation in lateral line morphology may allow fish in different habitats to differentially sense and respond to salient cues. Threespine sticklebacks (Gasterosteus aculeatus) occupy a diverse range of aquatic habitats; we therefore hypothesized that populations within the G. aculeatus species complex might show variation in the morphology of the lateral line sensory system. We sampled 16 threespine stickleback populations from marine, stream and lake (including benthic and limnetic) habitats and examined the distribution, type and number of neuromasts on different regions of the body. We found that the threespine stickleback has a reduced lateral line canal system, completely lacking canal neuromasts. Although the arrangement of lines of superficial neuromasts on the body was largely the same in all populations, the number of neuromasts within these lines varied across individuals, populations and habitats. In pairwise comparisons between threespine sticklebacks adapted to divergent habitats, we found significant differences in neuromast number. Stream residents had more neuromasts than marine sticklebacks living downstream in the same watershed. In two independent lakes, benthic sticklebacks had more trunk neuromasts than sympatric limnetic sticklebacks, providing evidence for parallel evolution of the lateral line system. Our data provide the first demonstration that the lateral line sensory system can vary significantly between individuals and among populations within a single species, and suggest that this sensory system may experience different selection regimes in alternative habitats.

Wark, A. R.; Peichel, C. L.

2010-01-01

334

Lateral line depigmentation (LLD) in channel catfish, Ictalurus punctatus (Rafinesque).  

PubMed

Head and lateral line erosion (HLLE) is a chronic dermatopathy affecting a number of fish that presents as depigmented skin along the lateral line system of the trunk and head. We present microbiological, immunological and histopathological features of this lesion in channel catfish, Ictalurus punctatus (Rafinesque), that developed after exposure to a chronic nutritional stress. Depigmention was limited to skin that was adjacent to the lateral line. The epidermis of affected fish was thin and reduced to a one-cell-thick layer over the lateral line. Melanocytes were depleted at the dermo-epidermal junction and formed aggregates in the epidermis. Innate immunity was weaker in affected fish than that previously measured in well-fed channel catfish. Because the pathology and apparent aetiology of HLLE described in various fish species are highly variable, HLLE appears to be a clinical sign, rather than a disease or syndrome. Thus, we propose that this clinical sign be referred to as lateral line depigmentation (LLD), because this description more accurately encompasses all cases of this presentation reported in fish. As nutritional requirements of channel catfish and lateral line neuroanatomy are well-known, the ability to reproducibly induce LLD in this species could provide a useful model for understanding its pathogenesis. PMID:19531093

Corrales, J; Ullal, A; Noga, E J

2009-08-01

335

Functional Anatomy, Pathomechanics, and Pathophysiology of Lateral Ankle Instability  

PubMed Central

Objective: To describe the functional anatomy of the ankle complex as it relates to lateral ankle instability and to describe the pathomechanics and pathophysiology of acute lateral ankle sprains and chronic ankle instability. Data Sources: I searched MEDLINE (1985–2001) and CINAHL (1982–2001) using the key words ankle sprain and ankle instability. Data Synthesis: Lateral ankle sprains are among the most common injuries incurred during sports participation. The ankle functions as a complex with contributions from the talocrural, subtalar, and inferior tibiofibular joints. Each of these joints must be considered in the pathomechanics and pathophysiology of lateral ankle sprains and chronic ankle instability. Lateral ankle sprains typically occur when the rearfoot undergoes excessive supination on an externally rotated lower leg. Recurrent ankle sprain is extremely common; in fact, the most common predisposition to suffering a sprain is the history of having suffered a previous ankle sprain. Chronic ankle instability may be due to mechanical instability, functional instability, or most likely, a combination of these 2 phenomena. Mechanical instability may be due to specific insufficiencies such as pathologic laxity, arthrokinematic changes, synovial irritation, or degenerative changes. Functional instability is caused by insufficiencies in proprioception and neuromuscular control. Conclusions/Recommendations: Lateral ankle sprains are often inadequately treated, resulting in frequent recurrence of ankle sprains. Appreciation of the complex anatomy and mechanics of the ankle joint and the pathomechanics and pathophysiology related to acute and chronic ankle instability is integral to the process of effectively evaluating and treating ankle injuries.

Hertel, Jay

2002-01-01

336

Lateral ventricle morphology analysis via mean latitude axis  

PubMed Central

Statistical shape analysis has emerged as an insightful method for evaluating brain structures in neuroimaging studies, however most shape frameworks are surface based and thus directly depend on the quality of surface alignment. In contrast, medial descriptions employ thickness information as alignment-independent shape metric. We propose a joint framework that computes local medial thickness information via a mean latitude axis from the well-known spherical harmonic (SPHARM-PDM) shape framework. In this work, we applied SPHARM derived medial representations to the morphological analysis of lateral ventricles in neonates. Mild ventriculomegaly (MVM) subjects are compared to healthy controls to highlight the potential of the methodology. Lateral ventricles were obtained from MRI scans of neonates (9–144 days of age) from 30 MVM subjects as well as age- and sex-matched normal controls (60 total). SPHARM-PDM shape analysis was extended to compute a mean latitude axis directly from the spherical parameterization. Local thickness and area was straightforwardly determined. MVM and healthy controls were compared using local MANOVA and compared with the traditional SPHARM-PDM analysis. Both surface and mean latitude axis findings differentiate successfully MVM and healthy lateral ventricle morphology. Lateral ventricles in MVM neonates show enlarged shapes in tail and head. Mean latitude axis is able to find significant differences all along the lateral ventricle shape, demonstrating that local thickness analysis provides significant insight over traditional SPHARM-PDM. This study is the first to precisely quantify 3D lateral ventricle morphology in MVM neonates using shape analysis.

Paniagua, Beatriz; Lyall, Amanda; Berger, Jean-Baptiste; Vachet, Clement; Hamer, Robert M; Woolson, Sandra; Lin, Weili; Gilmore, John; Styner, Martin

2013-01-01

337

Extra-articular Mimickers of Lateral Meniscal Tears  

PubMed Central

Context: Lateral meniscus tears are a common entity seen in sports medicine. Although lateral-side knee pain is often the result of a meniscus injury, several extra-articular pathologies share signs and symptoms with a meniscus tear. It is critical for the clinician to be able to identify and understand extra-articular pathologies that can present similar to a lateral meniscus tear. Evidence Acquisition: Data were collected through a thorough review of the literature conducted through a MEDLINE search for all relevant articles between 1980 and February 2010. Study Type: Clinical review. Results: Common extra-articular pathologies that can mimic lateral meniscal tears include iliotibial band syndrome, proximal tibiofibular joint instability, snapping biceps femoris or popliteus tendons, and peroneal nerve compression syndrome or neuritis. The patient history, physical examination features, and radiographic findings can be used to separate these entities from the more common intra-articular knee pathologies. Conclusions: In treating patients who present with lateral-sided knee pain, clinicians should be able to recognize and treat extra-articular pathologies that can present in a similar fashion as lateral meniscus tears.

Barker, Joseph U.; Strauss, Eric J.; Lodha, Sameer; Bach, Bernard R.

2011-01-01

338

Muscle forces and pronation stabilize the lateral ligament deficient elbow.  

PubMed

The influence of muscle activity and forearm position on the stability of the lateral collateral ligament deficient elbow was investigated in vitro, using a custom testing apparatus to simulate active and passive elbow flexion. Rotation of the ulna relative to the humerus was measured before and after sectioning of the joint capsule, and the radial and lateral ulnar collateral ligaments from the lateral epicondyle. Gross instability was present after lateral collateral ligament transection during passive elbow flexion with the arm in the varus orientation. In the vertical orientation during passive elbow flexion, stability of the lateral collateral ligament deficient elbow was similar to the intact elbow with the forearm held in pronation, but not similar to the intact elbow when maintained in supination. This instability with the forearm supinated was reduced significantly when simulated active flexion was done. The stabilizing effect of muscle activity suggests physical therapy of the lateral collateral ligament deficient elbow should focus on active rather than passive mobilization, while avoiding shoulder abduction to minimize varus elbow stress. Passive mobilization should be done with the forearm maintained in pronation. PMID:11451110

Dunning, C E; Zarzour, Z D; Patterson, S D; Johnson, J A; King, G J

2001-07-01

339

Hydrocode analysis of lateral stress gauges in shocked tantalum  

SciTech Connect

Experiments published by other workers, on the resistance change of manganin stress gauges embedded in a lateral orientation in tantalum targets shocked to a range of stresses, have been analysed using an adaptive mesh refinement hydrocode. It was found that for all of the four experiments the shape of the time profile of the computed lateral stress in the mounting layer closely matched the shape of the experimental lateral stress profiles. However, the calculated lateral stresses at the gauge location in the mounting layer are significantly less than the lateral stresses that would have been produced in the target if no gauge had been present. The perturbation caused by the gauge increased as the strength of the applied shock increased. When the perturbations are taken into account values of flow stress that are significantly smaller than those reported in the original research paper are derived. The work shows that the lateral gauge technique can give valuable information on strength provided high resolution simulation is used to compensate for the perturbations caused by the gauges.

Harris, E. J.; Winter, R. E. [Hydrodynamics Division, AWE, Aldermaston, Reading, Berkshire, RG7 4PR (United Kingdom)

2007-12-12

340

Lateral interactions in the perception of flicker and in the physiology of the lateral geniculate nucleus.  

PubMed

The perception of flicker strength in a center stimulus can be affected by the presence of a surrounding stimulus. We correlated this effect with the interactions between centers and surrounds of the receptive fields (RFs) of neurons in the retino-geniculate pathways. The responses of cells in the lateral geniculate nucleus (LGN) of two New World monkey species, the common marmoset (Callithrix jacchus), and the owl monkey (Aotus azarae) were measured to two spatially non-overlapping sinusoidally modulating luminance stimuli of equal temporal frequency, one of which mainly stimulated the RF center, the other the RF surround. The relative temporal phase between the center and surround stimuli was varied. The response amplitude as a function of relative phase between the center and surround stimuli can be described by a simple model where the RF center and surround responses are vector-added. A minimal response was reached for stimuli in which the surround stimulus led the center stimulus, indicating that the RF surround response lagged the center response. The flicker strength in the center stimulus perceived by human observers was measured psychophysically. It was found that the perceived flicker strength could be described by the same function as was used for the cell data. There were qualitative similarities between the physiological and the psychophysical data, suggesting that the physiological basis of the psychophysically measured spatial interactions is present as early as the LGN. The data indicated the presence of a nonlinearity in center-surround interactions that is influenced by the stimulus contrast. The possible source of this nonlinearity was studied by comparing the center and the surround responses with those in which they were selectively stimulated. PMID:15330708

Kremers, Jan; Kozyrev, Vladislav; Silveira, Luiz Carlos L; Kilavik, Bjørg Elisabeth

2004-08-01

341

Dynamics Study on Morphological Stabilities of Cellular Crystal Lateral Wall  

NASA Astrophysics Data System (ADS)

The lateral wall stabilities during the growing process of cellular crystal in the melt were studied in this article. The dynamics equation of cylindrical solid-liquid interface morphological stabilities in melt was first derived, and then the expression of criterion for cylindrical solid-liquid interface morphological stabilities was defined. The effect of the shape factor, solid radius, and other relevant factors on the morphological stabilities was analyzed. Also, the critical shape factor and critical growth rate for keeping the stabilities of the interface were determined. The phenomenon during the lateral growth process of ?-phase cellular crystal in carbon steel was observed under a high-temperature confocal scanning laser microscope (HTCSLM), which was used to verify the theoretical analysis and calculated results. The results indicate that the shape factor is beneficial to improving the stabilities of the cellular crystal lateral wall. During the increase process of the cellular crystal radius, however, there is a certain value of the cellular crystal radius, which induces the shape factor to reduce stabilities of the cellular crystal lateral wall rapidly. Even if the other conditions are unchanged, the shape of the cellular crystal may also cause the cellular crystal lateral wall to lose its stabilities. There are two critical growth rates to keep the cellular crystal lateral wall growing stably under the conditions of this research. For the Fe-0.15 pct C-0.8 pct Mn alloy, these two critical growth rates are 10-4 and 10 cm/s orders of magnitude, respectively. The difference between them is more than 105 times, so the slow critical growth rate conforms to the actual critical growth rate. The radius of the cellular crystal is the main influencing factor of lateral wall stabilities. The bigger the radius of the cellular crystal is, the worse the stabilities of the lateral wall are. That is also one of the reasons that the fine cellular crystal can survive during a certain period. The results of the theoretical analysis about stabilities of the cellular crystal lateral wall agree well with the lateral growth phenomena of ? phase cellular crystal in carbon steel observed by a HTCSLM. The theoretically calculated results of the radial critical growth rates are coincident with the experimental results.

Chang, Guowei; Chen, Shuying; Li, Qingchun; Yue, Xudong; Jin, Guangcan

2012-06-01

342

Fold patterns, lateral ramps and seismicity in central Pennsylvania  

USGS Publications Warehouse

The Susquehanna lateral ramp crosses the entire length of Pennsylvania in a NNE direction and extends into southern New York State. Its presence was first suspected because of a dramatic change in fold wavelength across the Susquehanna River, seen on both side-looking airborne radar (SLAR *) data and the geologic map of Pennsylvania. Seismic reflection profiles confirm the presence of a ramp and show the detailed nature of structures associated with it. These structures include antiformal stacks, juxtaposed anticlines and synclines, and folds beheaded by thrust faults. The change in the fold pattern, which led to recognizing the lateral ramp, occurs above a rapid dropoff in depth to the basement suggesting that the ramp and the basement configuration may somehow be related. In plan view, eleven earthquakes are spatially related to the Susquehanna lateral ramp, although they are in the basement rocks rather than in the cover rocks which contain the lateral ramp itself. The earthquakes are, therefore, not likely directly associated with the ramp, though they may be affiliated with strike-slip faulting in the basement which, itself, appears to be partly responsible for the formation of the ramp. The initial age of the faulting along, and in the vicinity of, the Susquehanna lateral ramp is presumably Early to Middle Paleozoic. However, the presence of a surficially-exposed Mesozoic dike along the ramp and modern seismicity suggest that the Susquehanna lateral ramp may be a zone of protracted, and perhaps repeated, tectonism which is currently being reactivated. A preliminary evaluation of the distribution of modern earthquakes in the Valley and Ridge, Blue Ridge and Appalachian Plateau shows that nearly half of the earthquakes are located under lateral ramps. If this observation is true, the presence of ramps may be a useful geological indicator of areas susceptible to seismicity. ?? 1991.

Pohn, H. A.; Coleman, Jr. , J. L.

1991-01-01

343

Hemispheric lateralization of verbal and spatial working memory during adolescence  

PubMed Central

Adult functional magnetic resonance imaging (fMRI) literature suggests that a left-right hemispheric dissociation may exist between verbal and spatial working memory (WM), respectively. However, investigation of this type has been obscured by incomparable verbal and spatial WM tasks and/or visual inspection at arbitrary thresholds as means to assess lateralization. Furthermore, it is unclear whether this hemispheric lateralization is present during adolescence, a time in which WM skills are improving, and whether there is a developmental association with laterality of brain functioning. This study used comparable verbal and spatial WM n-back tasks during fMRI and a bootstrap analysis approach to calculate lateralization indices (LI) across several thresholds to examine the potential of a left-right WM hemispheric dissociation in healthy adolescents. We found significant left hemispheric lateralization for verbal WM, most notably in the frontal and parietal lobes, as well as right hemisphere lateralization for spatial WM, seen in frontal and temporal cortices. Although no significant relationships were observed between LI and age or LI and performance, significant age-related patterns of brain activity were demonstrated during both verbal and spatial WM. Specifically, increased adolescent age was associated with less activity in the default mode brain network during verbal WM. In contrast, increased adolescent age was associated with greater activity in task-positive posterior parietal cortex during spatial working memory. Our findings highlight the importance of utilizing non-biased statistical methods and comparable tasks for determining patterns of functional lateralization. Our findings also suggest that, while a left-right hemispheric dissociation of verbal and spatial WM is apparent by early adolescence, age-related changes in functional activation during WM are also present.

Nagel, Bonnie J.; Herting, Megan M.; Maxwell, Emily C.; Bruno, Richard; Fair, Damien

2013-01-01

344

Lateral Flagella and Swarming Motility in Aeromonas Species  

PubMed Central

Swarming motility, a flagellum-dependent behavior that allows bacteria to move over solid surfaces, has been implicated in biofilm formation and bacterial virulence. In this study, light and electron microscopic analyses and genetic and functional investigations have shown that at least 50% of Aeromonas isolates from the species most commonly associated with diarrheal illness produce lateral flagella which mediate swarming motility. Aeromonas lateral flagella were optimally produced when bacteria were grown on solid medium for ?8 h. Transmission and thin-section electron microscopy confirmed that these flagella do not possess a sheath structure. Southern analysis of Aeromonas reference strains and strains of mesophilic species (n = 84, varied sources and geographic regions) with a probe designed to detect lateral flagellin genes (lafA1 and lafA2) showed there was no marked species association of laf distribution. Approximately 50% of these strains hybridized strongly with the probe, in good agreement with the expression studies. We established a reproducible swarming assay (0.5% Eiken agar in Difco broth, 30°C) for Aeromonas spp. The laf-positive strains exhibited vigorous swarming motility, whereas laf-negative strains grew but showed no movement from the inoculation site. Light and scanning electron microscopic investigations revealed that lateral flagella formed bacterium-bacterium linkages on the agar surface. Strains of an Aeromonas caviae isolate in which lateral flagellum expression was abrogated by specific mutations in flagellar genes did not swarm, proving conclusively that lateral flagella are required for the surface movement. Whether lateral flagella and swarming motility contribute to Aeromonas intestinal colonization and virulence remains to be determined.

Kirov, Sylvia M.; Tassell, Bronwen C.; Semmler, Annalese B. T.; O'Donovan, Lisa A.; Rabaan, Ali A.; Shaw, Jonathan G.

2002-01-01

345

Far lateral lumbar disc extrusion: MRI findings and surgical treatment.  

PubMed

This case report describes the magnetic resonance imaging (MRI) findings and the treatment of a far lateral extrusion of disc material at the sixth and seventh lumbar vertebrae (L6-L7) in a five-year-old male Alpine Dachsbracke dog referred to our hospital for investigation of the complaint of a one week progressive lameness in the left pelvic limb and poorly localized back pain. An extra-foraminal left lateral disc herniation impinging on the sixth lumbar nerve root was diagnosed by MRI examinations. Due to the far lateral position of the extruded disc material on MRI, surgical opening of the spinal canal was not necessary. Removal of the herniated soft disc material impinging on the L6 nerve root, and fenestration of the L6-L7 disc was performed laterally. To the author's knowledge 'far-lateral' disc herniation beyond the neuroforamen without any spinal canal contact has not been described in dogs until now. A complete recovery with no evidence of pain was achieved only after a couple of weeks after surgery. We acknowledge that it is possible that other pathological mechanisms may have contributed to clinical signs and to a delayed recovery. PMID:23857574

Fadda, A; Lang, J; Forterre, F

2013-01-01

346

The lateral periodontal cyst: aetiology, clinical significance and diagnosis.  

PubMed

The lateral periodontal cyst (LPC) is a relatively uncommon but widely recognized odontogenic cyst of developmental origin. It is found mostly in adults and has no sex predilection. LPC is usually discovered during routine radiographic examination, is located mainly between the roots of vital mandibular canines and premolars, and seldom causes pain or other clinical symptoms. The defect appears on radiographs as a round or teardrop-shaped, well circumscribed radiolucency. Due to its location it can easily be misdiagnosed as a lesion of endodontic origin. In this paper, two cases of lateral periodontal cysts are presented. In the first case, the patient (woman, 62 years old) complained of an asymptomatic gingival swelling in the region between the right maxillary canine and premolar. The radiographic examination revealed a well circumscribed radiolucency with a radiopaque margin between the roots of the canine and premolar. The adjacent teeth had vital pulp. Surgical enucleation of the lesion was performed and the histological examination revealed that the lesion was a "lateral periodontal cyst of developmental origin". In the second case, the patient (women, 44 years old) complained of a swelling in the area of tooth 32. During radiographic examination a well circumscribed radiolucency between the roots of the lateral incisor and the canine was discovered. Surgical enucleation of the lesion was performed and the histological examination revealed that the lesion was a "lateral periodontal cyst of developmental origin". PMID:11202873

Kerezoudis, N P; Donta-Bakoyianni, C; Siskos, G

2000-08-01

347

Lateral hyporheic exchange throughout the Mississippi River network  

NASA Astrophysics Data System (ADS)

River water circulates vertically through the river bed and laterally through bank sediments. This hyporheic exchange brings river water into contact with microbes in the adjacent sediments, otherwise known as the hyporheic exchange zone. As such, hyporheic zones act as hotspots for the biogeochemical cycling of carbon, metals and nutrients in rivers, and can, for example, influence the export of nitrogen to downstream ecosystems. Here, we calculate the extent and duration of lateral hyporheic exchange throughout the Mississippi River network, using a physics-based numerical model that takes into account the distribution of groundwater baseflow, river discharge, alluvium permeability and river morphology. We find that in our simulations, lateral exchange occurs throughout the network: practically all of the river water that reaches the mouth of the Mississippi River network has circulated through the lateral hyporheic zone. River water residence time in the hyporheic zone ranges from less than an hour in headwaters to over a month in larger channels. Comparison of the residence times that we derive to a previously reported residence time threshold for denitrification suggests that around one quarter of the lateral hyporheic zones in the Mississippi River network favour denitrification, and thus nitrogen loss. Given that river water can circulate many times through the river bank before reaching the river mouth, and can undergo vertical exchange with the river bed, we suggest that our estimates serve as a lower limit for potential nitrogen loss.

Kiel, Brian A.; Bayani Cardenas, M.

2014-06-01

348

Fractures of the acromion and the lateral scapular spine.  

PubMed

We studied 37 fractures lateral to the spinoglenoidal notch to evaluate the validity of collectively handling these fractures as an acromion fracture and to ascertain the mechanism of injury. We divided them into three groups according to the location of the fracture line. Fracture of the anatomic acromion or the extremely lateral scapular spine (groups I and II, 28 fractures) was frequently associated with fracture of the coracoid base, acromioclavicular joint injury, or both. The mechanism of injury in most cases was presumed to be indirect force brought to bear on the shoulder from the lateral direction. Fracture descending to the spinoglenoidal notch (group III, nine fractures) was seldom associated with other shoulder injuries, and surgery was rarely needed. The mechanism was assumed to be direct force brought to bear on the shoulder from the posterior direction. Therefore fractures of the anatomic acromion and the extremely lateral scapular spine may be managed collectively. However, fracture descending to the spinoglenoidal notch should be managed separately. We advocate that these fractures should be classified into two types in terms of clinical consideration: type I fractures, comprising those of the anatomic acromion and the extremely lateral scapular spine, and type II fractures, located in the more medial spine and descending to the spinoglenoidal notch. PMID:9437604

Ogawa, K; Naniwa, T

1997-01-01

349

Socially dependent auditory laterality in domestic horses (Equus caballus).  

PubMed

Laterality is now known to be an ubiquitous phenomenon among the vertebrates. Particularly, laterality of auditory processing has been demonstrated in a variety of species, especially songbirds and primates. Such a hemispheric specialization has been shown to depend on factors such as sound structure, species specificity and types of stimuli. Much less is known on the possible influence of social familiarity although a few studies suggest such an influence. Here we tested the influence of the degree of familiarity on the laterality of the auditory response in the domestic horse. This species is known for its social system and shows visible reactions to sounds, with one or two ears moving towards a sound source. By comparing such responses to the playback of different conspecific whinnies (group member, neighbor and stranger), we could demonstrate a clear left hemisphere (LH) preference for familiar neighbor calls while no preference was found for group member and stranger calls. Yet, we found an opposite pattern of ear side preference for neighbor versus stranger calls. These results are, to our knowledge, the first to demonstrate auditory laterality in an ungulate species. They open further lines of thought on the influence of the social "value" of calls and the listener's arousal on auditory processing and laterality. PMID:19283416

Basile, Muriel; Boivin, Sarah; Boutin, Anaïs; Blois-Heulin, Catherine; Hausberger, Martine; Lemasson, Alban

2009-07-01

350

Lateral position detection and control for friction stir systems  

SciTech Connect

A friction stir system for processing at least a first workpiece includes a spindle actuator coupled to a rotary tool comprising a rotating member for contacting and processing the first workpiece. A detection system is provided for obtaining information related to a lateral alignment of the rotating member. The detection system comprises at least one sensor for measuring a force experienced by the rotary tool or a parameter related to the force experienced by the rotary tool during processing, wherein the sensor provides sensor signals. A signal processing system is coupled to receive and analyze the sensor signals and determine a lateral alignment of the rotating member relative to a selected lateral position, a selected path, or a direction to decrease a lateral distance relative to the selected lateral position or selected path. In one embodiment, the friction stir system can be embodied as a closed loop tracking system, such as a robot-based tracked friction stir welding (FSW) or friction stir processing (FSP) system.

Fleming, Paul (Boulder, CO); Lammlein, David (Houston, TX); Cook, George E. (Brentwood, TN); Wilkes, Don Mitchell (Nashville, TN); Strauss, Alvin M. (Nashville, TN); Delapp, David (Ashland City, TN); Hartman, Daniel A. (Santa Fe, NM)

2010-12-14

351

Dogs show left facial lateralization upon reunion with their owners.  

PubMed

Domestic dogs demonstrate behavioral laterality in response to emotional stimuli; those responses include tail wagging and head turning. The dog is the species with the closest relationship to humans; dogs can express strong social emotions (e.g., attachment and separation anxiety) to specific persons, such as their owners. In this study, we examined whether dogs demonstrate more facial laterality when reunited with their owners than when they encounter an unfamiliar person in an unfamiliar situation. We also examined whether the observed laterality was specific to positive social stimuli (i.e., the owner) or a general response to nonsocial positive stimuli (i.e., toys). The dogs' facial expressions were recorded by a high-speed video camera during the presentation of emotional stimuli and the acceleration rates of parts of their faces were analyzed. The results showed that the left eyebrow moved more when the owner was present than at baseline. No bias in terms of eyebrow movement was observed when the dogs saw attractive toys. These results suggest that dogs show facial laterality in response to emotional stimuli. This laterality was specific to social stimuli, probably reflecting the dog's attachment to the owner. PMID:23727034

Nagasawa, Miho; Kawai, Emi; Mogi, Kazutaka; Kikusui, Takefumi

2013-09-01

352

Embryonic exposure to predator odour modulates visual lateralization in cuttlefish  

PubMed Central

Predation pressure acts on the behaviour and morphology of prey species. In fish, the degree of lateralization varies between high- and low-predation populations. While lateralization appears to be widespread in invertebrates, we do not know whether heredity and early experience interact during development as in vertebrates. Here we show, for the first time, that an exposure to predator odour prior to hatching modulates visual lateralization in newly hatched cuttlefish. Only cuttlefish that have been exposed to predator odour display a left-turning bias when tested with blank seawater in a T-shaped apparatus. Exposure to predator odour all the incubation long could appear as an acute predictor of a high-predation surrounding environment. In addition, cuttlefish of all groups display a left-turning preference when tested with predator odour in the apparatus. This suggests the ability of cuttlefish to innately recognize predator odour. To our knowledge, this is the first clear demonstration that lateralization is vulnerable to ecological challenges encountered during embryonic life, and that environmental stimulation of the embryo through the olfactory system could influence the development of subsequent visual lateralization.

Jozet-Alves, Christelle; Hebert, Marie

2013-01-01

353

Anterior horn lateral meniscus tear, repair, and meniscectomy.  

PubMed

The purpose of this study was to describe the effect of anterior horn of the lateral meniscus (AHLM) tears on tibiofemoral contact pressures and the ability to restore normal parameters with repair. Eight fresh-frozen cadaveric knees were used. The specimens were subjected to a load of 1,000?N at 0 and 30 degrees of flexion and peak pressure, force and contact area were recorded. The test was repeated for four different instances. Peak force in the lateral compartment was significantly increased at 0 degrees of knee flexion from 37?N intact to 47?N after the tear and 56?N postmeniscectomy. At 0 degrees of knee flexion, the peak pressure of the lateral meniscus was significantly increased from 1.1 MPa in the intact state to 1.9 MPa after meniscectomy. The peak pressure in the nontraumatized medial compartment was significantly increased after partial lateral meniscectomy (p?lateral compartments with a tear of the AHLM. It also showed an increase in peak contact pressure after meniscectomy. With repair, the preinjury condition peak forces were restored to normal, suggesting the importance of repairing tears of the AHLM. PMID:24227397

Prince, Matthew R; Esquivel, Amanda O; Andre, Allison M; Goitz, Henry T

2014-06-01

354

Hydrocode Analysis of Lateral Stress Gauges in Shocked Tantalum  

NASA Astrophysics Data System (ADS)

Experiements published by other workers on the resistance change of manganin stress gauges embedded in a lateral orientation in Tantalum targets have been analysed using an Adaptive Mesh Refinement Hydrocode. It was found that for four experiments the shape of the time profile of the computed lateral stress in the mounting layer closely matched the shape of the experimental lateral stress profiles. However, the calculated lateral stresses at the gauge location in the mounting layer are significantly less than the stresses that would have been produced in the target if no gauge had been present. The perturbation caused by the gauge increased as the strength of the applied shock increased. When the perturbations are taken into account values of flow stress that are significantly smaller than those reported in the original research paper are derived. The work demonstrates that the lateral gauge technique can give valuable information on strength provided high resolution simulation is used to compensate for the perturbations caused by the gauges.

Harris, Ernest; Winter, Ron

2007-06-01

355

An assay for lateral line regeneration in adult zebrafish.  

PubMed

Due to the clinical importance of hearing and balance disorders in man, model organisms such as the zebrafish have been used to study lateral line development and regeneration. The zebrafish is particularly attractive for such studies because of its rapid development time and its high regenerative capacity. To date, zebrafish studies of lateral line regeneration have mainly utilized fish of the embryonic and larval stages because of the lower number of neuromasts at these stages. This has made quantitative analysis of lateral line regeneration/and or development easier in the earlier developmental stages. Because many zebrafish models of neurological and non-neurological diseases are studied in the adult fish and not in the embryo/larvae, we focused on developing a quantitative lateral line regenerative assay in adult zebrafish so that an assay was available that could be applied to current adult zebrafish disease models. Building on previous studies by Van Trump et al. that described procedures for ablation of hair cells in adult Mexican blind cave fish and zebrafish (Danio rerio), our assay was designed to allow quantitative comparison between control and experimental groups. This was accomplished by developing a regenerative neuromast standard curve based on the percent of neuromast reappearance over a 24 hr time period following gentamicin-induced necrosis of hair cells in a defined region of the lateral line. The assay was also designed to allow extension of the analysis to the individual hair cell level when a higher level of resolution is required. PMID:24747778

Pisano, Gina C; Mason, Samantha M; Dhliwayo, Nyembezi; Intine, Robert V; Sarras, Michael P

2014-01-01

356

Control of somite patterning by signals from the lateral plate.  

PubMed Central

The body musculature of higher vertebrates is composed of the epaxial muscles, associated with the vertebral column, and of the hypaxial muscles of the limbs and ventro-lateral body wall. Both sets of muscles arise from different cell populations within the dermomyotomal component of the somite. Myogenesis first occurs in the medial somitic cells that will form the epaxial muscles and starts with a significant delay in cells derived from the lateral somitic moiety that migrate to yield the hypaxial muscles. The newly formed somite is mostly composed of unspecified cells, and the determination of somitic compartments toward specific lineages is controlled by environmental cues. In this report, we show that determinant signals for lateral somite specification are provided by the lateral plate. They result in a blockade of the myogenic program, which maintains the lateral somitic cells as undifferentiated muscle progenitors expressing the Pax-3 gene, and represses the activation of the MyoD family genes. In vivo, this mechanism could account for the delay observed in the onset of myogenesis between muscles of the epaxial and hypaxial domains. Images Fig. 2 Fig. 3

Pourquie, O; Coltey, M; Breant, C; Le Douarin, N M

1995-01-01

357

Reconstrução do ligamento cruzado anterior: impacto do desempenho muscular e funcional no retorno ao mesmo nível de atividade pré-lesão  

Microsoft Academic Search

RESUMO Introdução: A reconstrução do LCA objetiva restabelecer a biome- cânica e minimizar a instabilidade do joelho. Objetivo: comparar performance muscular, funcional e frouxidão ligamentar, entre voluntários que retornaram ao mesmo nível de atividade pré-lesão e aqueles que não retornaram, após a reconstrução ligamentar. Métodos: 25 homens, operados pelo mesmo cirurgião, com o ligamento patelar, via artroscopia e mais de

Lygia Paccini Lustosa; Sérgio Teixeira da Fonseca; Marco Antônio Percope de Andrade

2007-01-01

358

A theory for lateral wing-tip blowing  

NASA Technical Reports Server (NTRS)

The concept of lateral blowing consists in utilizing thin jets of air, which are ejected in the spanwise direction from slots at the tips of straight and swept wings, or along the leading edges of delta wings, to generate aerodynamic forces without the assistance of deflecting solid surfaces. For weak intensities of blowing the so-generated forces could be used for roll and lateral control of aircraft. In this work a theory for this concept as applied to straight wings is presented, revealing the analytical relationship between blowing and aerodynamic forces. The approach is based on perturbing the span of an elliptically loaded wing. Scaling laws involving blowing intensity, aspect ratio, and angle of attack are derived and compared with experiments. It is concluded that this concept has potential as a novel roll and lateral control device.

Tavella, D.; Roberts, L.

1985-01-01

359

Lateral vibration effects in atomic-scale friction  

NASA Astrophysics Data System (ADS)

The influence of lateral vibrations on the stick-slip motion of a nanotip elastically pulled on a flat crystal surface is studied by atomic force microscopy measurements on a NaCl(001) surface in ultra-high vacuum. The slippage of the nanotip across the crystal lattice is anticipated at increasing driving amplitude, similarly to what is observed in presence of normal vibrations. This lowers the average friction force, as explained by the Prandtl-Tomlinson model with lateral vibrations superimposed at finite temperature. Nevertheless, the peak values of the lateral force, and the total energy losses, are expected to increase with the excitation amplitude, which may limit the practical relevance of this effect.

Roth, R.; Fajardo, O. Y.; Mazo, J. J.; Meyer, E.; Gnecco, E.

2014-02-01

360

Strategies of Healthy Adults Walking on a Laterally Oscillating Treadmill  

NASA Technical Reports Server (NTRS)

We mounted a treadmill on top of a six degree-of-freedom motion base platform to investigate locomotor responses produced by healthy adults introduced to a dynamic walking surface. The experiment examined self-selected strategies employed by participants when exposed to continuous, sinusoidal lateral motion of the support surface while walking. Torso translation and step width were used to classify responses used to stabilize gait in a novel, dynamic environment. Two response categories emerged. Participants tended to either fix themselves in space (FIS), allowing the treadbelt to move laterally beneath them, or they fixed themselves to the base (FTB), moving laterally as the motion base oscillated. The degree of fixation in both extremes varied across participants. This finding suggests that normal adults have innate and varied preferences for reacquiring gait stability, some depending more heavily on vision (FIS group) and others on proprioception (FTB group). Keywords: Human locomotion, Unstable surface, Treadmill, Adaptation, Stability

Brady, Rachel A.; Peters, Brian T.; Bloomberg, Jacob J.

2008-01-01

361

Vehicle Lateral State Estimation Based on Measured Tyre Forces  

PubMed Central

Future active safety systems need more accurate information about the state of vehicles. This article proposes a method to evaluate the lateral state of a vehicle based on measured tyre forces. The tyre forces of two tyres are estimated from optically measured tyre carcass deflections and transmitted wirelessly to the vehicle body. The two remaining tyres are so-called virtual tyre sensors, the forces of which are calculated from the real tyre sensor estimates. The Kalman filter estimator for lateral vehicle state based on measured tyre forces is presented, together with a simple method to define adaptive measurement error covariance depending on the driving condition of the vehicle. The estimated yaw rate and lateral velocity are compared with the validation sensor measurements.

Tuononen, Ari J.

2009-01-01

362

Issues Related to Lateral Stress Measurements in Alumina Ceramics  

NASA Astrophysics Data System (ADS)

Failure fronts or ``waves'' in brittle materials have been the subject of extensive research. This is a phenomenon where a damage front propagates behind the main shock wave and reduces the strength. It is reported to be observed by means of embedded lateral gauges where it manifests itself as a two-step structure. Such profiles were obtained when impacts were performed using copper flyers. Later, it was shown that this second rise in lateral stress was not evident in ceramic targets when either a ceramic projectile plate was employed or a thin ceramic cover plate was mounted on the front of the target. We now extend the use of different projectile materials such as heat treated 4340 steel and tungsten. We find that the second step is not evident and may instead be an effect of the experimental parameters and not related to the failure front.

Field, J. E.; Tsembelis, K.; Brar, N. S.; Proud, W. G.; Dandekar, D. P.; Rosenberg, Z.

2004-07-01

363

Lateralized P3 Deficit in Schizotypal Personality Disorder  

PubMed Central

Background Reduced, left-lateralized P3 amplitude has been reported in several studies focusing on electrophysiologic function in schizophrenia. Also, several lines of evidence suggest a similarity between schizophrenia and schizotypal personality disorder (SPD). This study was undertaken to determine the replicability of our previous finding of a left-lateralized P3 amplitude deficit in SPD. Methods We recorded event-related potentials in 21 SPD and 18 normal control subjects in an auditory “oddball” P3 paradigm. Results In the SPD subjects, but not in the control subjects, there was lower P3 amplitude at T3 compared with T4. Conclusions These results are similar to the ones in our previous work and further support the presence of a left-lateralized P3 deficit in SPD.

Niznikiewicz, Margaret A.; Voglmaier, Martina M.; Shenton, Martha E.; Dickey, Chandlee C.; Seidman, Larry J.; Teh, EngKeat; Van Rhoads, Richard; McCarley, Robert W.

2010-01-01

364

Vehicle lateral state estimation based on measured tyre forces.  

PubMed

Future active safety systems need more accurate information about the state of vehicles. This article proposes a method to evaluate the lateral state of a vehicle based on measured tyre forces. The tyre forces of two tyres are estimated from optically measured tyre carcass deflections and transmitted wirelessly to the vehicle body. The two remaining tyres are so-called virtual tyre sensors, the forces of which are calculated from the real tyre sensor estimates. The Kalman filter estimator for lateral vehicle state based on measured tyre forces is presented, together with a simple method to define adaptive measurement error covariance depending on the driving condition of the vehicle. The estimated yaw rate and lateral velocity are compared with the validation sensor measurements. PMID:22291535

Tuononen, Ari J

2009-01-01

365

Eliminating lateral violence in the ambulatory setting: one center's strategies.  

PubMed

Lateral violence (eg, disruptive, disparaging, or uncivil behavior inflicted by one peer on another) creates an unpleasant work environment that can have harmful effects on individual nurses, team members, patients, and the bottom line of the health care organization. Educating nurses about the most common forms of lateral violence and strategies for handling inappropriate behavior can be the first step toward eliminating this behavior. Effective nursing leaders develop and maintain a "zero-tolerance" culture that includes clear and concise behavioral expectations and consequences for employees who exhibit unprofessional behavior. Use of a code of conduct, open communication, and quick resolution of issues that arise are strategies that one ambulatory surgery center has used to successfully combat lateral violence in the workplace. PMID:21530706

Dimarino, Tina J

2011-05-01

366

Extradural Dermoid Cyst Located in the Lateral Sphenoid Ridge  

PubMed Central

Dermoid cysts are rare congenital tumors that occur primarily at the midline at a characteristic intradural location. However, dermoid cysts located at extradural and lateral regions have been rarely reported until now. In the present study, the authors demonstrate the unusual instance of an intracranial extradural dermoid cyst at the lateral sphenoid ridge. A 53-year-old woman admitted because of progressive headache and dizziness. The patient had no neurologic deficits, and magnetic resonance imaging with no contrast enhancement revealed a mass at the right sphenoid ridge. The mass was accompanied with sphenoid bone erosion visible on computed tomography. The patient underwent right pterional craniotomy, and the tumor including the capsule was totally resected. Presence of a dermoid cyst was confirmed with histopathological examination. The patient had no complications during the postoperative period. This study suggests that dermoid cyst should be considered for differential diagnosis of extradural and lateral intracranial masses.

Ko, Seok-Jin; Park, Kyung-Jae; Park, Dong-Hyuk

2014-01-01

367

Pilot opinions of sampling effects in lateral-directional control  

NASA Technical Reports Server (NTRS)

Flight experiments with a microprocessor control system were conducted to determine the effects of variations in sampling parameters on several pilots' opinions of lateral-directional flying qualities. Princeton's variable-response research aircraft (VRA), which is equipped with a microprocessor based digital flight control system (Micro-DFCS), was the test vehicle. Two U.S. Navy pilots evaluated the effects of sampling rate, quantization, and pure time delay during tracking, approach, and landing. Aircraft carrier approach tasks were conducted using a Navy approach mirror. Acquisition and tracking of fixed objects on the ground provided additional information related to the Navy misson. The longitudinal controls were implemented with analog electronics, while the lateral-directional pilot inputs (stick and rudder) were fed to the Micro-DFCS, which commanded the ailerons and rudder. The conceptual relationship between the evaluation pilot's lateral-directional inputs, the flight computer, and the aircraft are illustrated.

Stengel, R. F.; Miller, G. E.

1982-01-01

368

Damping lateral vibrations in rotary machinery using motor speed modulation  

NASA Astrophysics Data System (ADS)

This paper outlines a new principle for damping lateral vibrations of rotary systems. According to this principle, no changes in the visco-elastic properties of the system to be damped are required. The method is based on the generation of a harmonic additive to the constant speed of rotation that provides significant damping of lateral vibrations at critical speeds of rotation. This concept is validated analytically using the method of averaging and additionally with the help of direct numerical integration. The solution is shown to represent Fourier series containing Bessel functions. Consequently, proper choice of the parameters of the additional harmonic component ensuring that the Bessel functions have minimum values results from a minimization of the solution itself. Thus, the analytical solution and numerical results prove this concept by showing an essential decrease of the amplitudes of lateral vibrations of the damped system compared with those of the undamped system. The physical explanation of this effect is presented.

Verichev, Nikolai N.; Verichev, Stanislav N.; Erofeyev, Vladimir I.

2010-01-01

369

Current fit of medial and lateral unicompartmental knee arthroplasty  

PubMed Central

Whether failure in unicompartmental knee arthroplasty (UKA) is related to implant design remains unclear. We hypothesize that current available UKAs fit within 2 mm. Forty-eight CTs of cadaveric knees were compared to current available UKA brands. Overall no-fit compared to at least one component within 2 mm is high (91.7%) and worse for males (100%) compared to females (83.3%). Good fit was observed for the medial but not for the lateral tibia plateau. Seven males (29.2%) had larger dimensions of more than 2 mm. For the widest UKA brand, 12 (57%) males and 2 females (8. 3%) had lateral femoral condyles 3 mm larger. Current UKA's in our sample population fit less on the lateral tibia and on femoral condyles.

Fitz, Wolfgang; Bliss, Robin; Losina, Elena

2014-01-01

370

Giant negative and positive lateral shifts in graphene superlattices  

NASA Astrophysics Data System (ADS)

Electronic analogy of Goos-Hänchen shift has been well established and investigated in various graphene-based nanostructures, including p-n interface, single and double barriers. In this paper, we have studied the giant negative and positive lateral shifts of the transmitted electron beam through graphene superlattices. It is found that the lateral shifts, depending on the location of new Dirac point, can be negative as well as positive near the band edges of zero-k? (non-Bragg) gap. We have also achieved the enhanced opposite shifts in the graphene superlattice with defect layer, since such structure possesses the defect mode inside the zero-k? gap. The modulations of negative and positive lateral shifts by incidence angles, width and potential height of defect layer may lead to potential applications in the graphene-based electron wave devices.

Chen, Xi; Zhao, Pei-Liang; Lu, Xiao-Jing

2013-05-01

371

The study of piezoelectric lateral-electric-field-excited resonator.  

PubMed

The piezoelectric lateral-electric-field-excited resonator based on an X-cut lithium niobate plate has been investigated. Two rectangular electrodes were applied on one side of the plate so that the lateral electric field components were parallel to the crystallographic Y-axis and excited the longitudinal wave in the gap between the electrodes. The region around the electrodes was covered with a special absorbing varnish to suppress the spurious oscillations. The effect of the absorbing coating width on the resonant frequency and Q-factor of the lateral field-excited resonator was studied in detail with the series and parallel resonances for different width of the gap between the electrodes. As a result, we found experimentally the parameter regions of pure resonances and the boundaries of value variation for resonance frequency, Q-factor, and effective electromechanical coupling coefficient. PMID:24402903

Zaitsev, Boris; Kuznetsova, Iren; Shikhabudinov, Alexander; Teplykh, Andrey; Borodina, Irina

2014-01-01

372

Nucleation-mediated lateral growth on foreign substrate  

SciTech Connect

A model is developed to deal with lateral growth of a crystalline layer on a foreign substrate, which is mediated by successive nucleation at the concave corner defined by the meeting of a crystal facet and the substrate. It is demonstrated that due to an imbalance of surface/interface tensions at the concave corner, once the embryo of a nucleus is formed, the crystallographic orientation of the nucleus is spontaneously twisted. By successive nucleation at the concave corner, the crystalline layer develops laterally on the substrate, with its crystallographic orientation continuously rotated. In this way, a regular spatial pattern with well-defined long-range order is eventually achieved. Our model provides a criterion to predict when such an effect becomes observable in the nucleation-mediated lateral growth. The theoretical expectations are consistent with the experimental observations.

Shu, Da-Jun [unknown; Wang, Mu [Chinese Academy of Sciences; Liu, Feng [ORNL; Zhang, Zhenyu [ORNL; Peng, Ru-Wen [unknown; Zhang, Rong [unknown; Ming, Nai-Ben [unknown

2007-01-01

373

Comparative squamation of the lateral line canal pores in sharks.  

PubMed

The current study collected the first quantitative data on lateral line pore squamation patterns in sharks and assessed whether divergent squamation patterns are similar to experimental models that cause reduction in boundary layer turbulence. In addition, the hypothesis that divergent orientation angles are exclusively found in fast-swimming shark species was tested. The posterior lateral line and supraorbital lateral line pore squamation of the fast-swimming pelagic shortfin mako shark Isurus oxyrinchus and the slow-swimming epi-benthic spiny dogfish shark Squalus acanthias was examined. Pore scale morphology and pore coverage were qualitatively analysed and compared. In addition, pore squamation orientation patterns were quantified for four regions along the posterior lateral line and compared for both species. Isurus oxyrinchus possessed consistent pore scale coverage among sampled regions and had a divergent squamation pattern with multiple scale rows directed dorsally and ventrally away from the anterior margin of the pore with an average divergent angle of 13° for the first row of scales. Squalus acanthias possessed variable amounts of scale coverage among the sampled regions and had a divergent squamation pattern with multiple scale rows directed ventrally away from the anterior margin of the pore with an average angle of 19° for the first row of scales. Overall, the squamation pattern measured in I. oxyrinchus fell within the parameters used in the fluid flow analysis, which suggests that this pattern may reduce boundary layer turbulence and affect lateral line sensitivity. The exclusively ventral oriented scale pattern seen in S. acanthias possessed a high degree of divergence but the pattern did not match that of the fluid flow models. Given current knowledge, it is unclear how this would affect boundary layer flow. By studying the relationship between squamation patterns and the lateral line, new insights are provided into sensory biology that warrant future investigation due to the implications for the ecology, morphology and sensory evolution of sharks. PMID:24655049

McKenzie, R W; Motta, P J; Rohr, J R

2014-05-01

374

Patterns of prokaryotic lateral gene transfers affecting parasitic microbial eukaryotes  

PubMed Central

Background The influence of lateral gene transfer on gene origins and biology in eukaryotes is poorly understood compared with those of prokaryotes. A number of independent investigations focusing on specific genes, individual genomes, or specific functional categories from various eukaryotes have indicated that lateral gene transfer does indeed affect eukaryotic genomes. However, the lack of common methodology and criteria in these studies makes it difficult to assess the general importance and influence of lateral gene transfer on eukaryotic genome evolution. Results We used a phylogenomic approach to systematically investigate lateral gene transfer affecting the proteomes of thirteen, mainly parasitic, microbial eukaryotes, representing four of the six eukaryotic super-groups. All of the genomes investigated have been significantly affected by prokaryote-to-eukaryote lateral gene transfers, dramatically affecting the enzymes of core pathways, particularly amino acid and sugar metabolism, but also providing new genes of potential adaptive significance in the life of parasites. A broad range of prokaryotic donors is involved in such transfers, but there is clear and significant enrichment for bacterial groups that share the same habitats, including the human microbiota, as the parasites investigated. Conclusions Our data show that ecology and lifestyle strongly influence gene origins and opportunities for gene transfer and reveal that, although the outlines of the core eukaryotic metabolism are conserved among lineages, the genes making up those pathways can have very different origins in different eukaryotes. Thus, from the perspective of the effects of lateral gene transfer on individual gene ancestries in different lineages, eukaryotic metabolism appears to be chimeric.

2013-01-01

375

Dynamic biomechanics of the human head in lateral impacts  

PubMed Central

The biomechanical responses of human head (translational head CG accelerations, rotational head accelerations, and HIC) under lateral impact to the parietal-temporal region were investigated in the current study. Free drop tests were conducted at impact velocities ranging from 2.44 to 7.70 m/s with a 40 durometer, a 90 durometer flat padding, and a 90 durometer cylinder. Specimens were isolated from PMHS subjects at the level of occipital condyles, and the intracranial substance was replaced with brain simulant (Sylgard 527). Three tri-axial accelerometers were instrumented at the anterior, posterior, and vertex of the specimen, and a pyramid nine accelerometer package (pNAP) was used at the contra-lateral site. Biomechanical responses were computed by transforming accelerations measured at each location to the head CG. The results indicated significant “hoop effect” from skull deformation. Translational head CG accelerations were accurately measured by transforming the pNAP, the vertex accelerations, or the average of anterior/posterior acceleration to the CG. The material stiffness and structural rigidity of the padding changed the biomechanical responses of the head with stiffer padding resulting in higher head accelerations. At the skull fracture, HIC values were more than 2–3x higher than the frontal skull fracture threshold (HIC=1000), emphasizing the differences between frontal and lateral impact. Rotational head accelerations up to 42.1 krad/s2 were observed before skull fracture, indicating possible severe brain injury without skull fracture in lateral head impact. These data will help to establish injury criteria and threshold in lateral impacts for improved automotive protection and help clinicians understand the biomechanics of lateral head impact from improved diagnosis.

Zhang, Jiangyue; Yoganandan, Narayan; Pintar, Frank A.

2009-01-01

376

Reconstruction of the corneal topography from lateral-shearing interferograms  

NASA Astrophysics Data System (ADS)

The paper presents an approach for measurements of the corneal topography by use of lateral-shearing interferometry. In shearing interferometry the wavefront reflected from the object is split in two wavefronts. The introduction of lateral shift and superposition of the wavefronts produces interference pattern. We used phase shifting algorithm to obtain the phase differences of the wavefront reflected from the cornea. The measurements of the phase differences are carried out in two orthogonal directions. The phase of the wavefront is reconstructed by use of algorithm for the large grid based on the discrete integration. The computer-generated interferograms are used to test the procedure and to estimate its accuracy.

Licznerski, Tomasz J.; Kasprzak, Henryk T.

1999-07-01

377

Two-dimensional spin diffusion in multiterminal lateral spin valves  

NASA Astrophysics Data System (ADS)

The effects of two-dimensional spin diffusion on spin extraction in lateral semiconductor spin valves have been investigated experimentally and theoretically. A ferromagnetic collector terminal of variable size is placed between the ferromagnetic electron spin injector and detector of a conventional lateral spin valve for spin extraction. It is observed that transverse spin diffusion beneath the collector terminal plays an important role along with the conventional longitudinal spin diffusion in describing the overall transport of spin carriers. Two-dimensional spin diffusion reduces the perturbation of the channel electrochemical potentials and improves spin extraction.

Saha, D.; Basu, D.; Holub, M.; Bhattacharya, P.

2008-01-01

378

LATERAL GENE TRANSFER AND THE HISTORY OF BACTERIAL GENOMES  

SciTech Connect

The aims of this research were to elucidate the role and extent of lateral transfer in the differentiation of bacterial strains and species, and to assess the impact of gene transfer on the evolution of bacterial genomes. The ultimate goal of the project is to examine the dynamics of a core set of protein-coding genes (i.e., those that are distributed universally among Bacteria) by developing conserved primers that would allow their amplification and sequencing in any bacterial taxa. In addition, we adopted a bioinformatic approach to elucidate the extent of lateral gene transfer in sequenced genome.

Howard Ochman

2006-02-22

379

Non-uniform lateral current distribution in quantum cascade lasers.  

PubMed

Non-uniform lateral current distribution in quantum cascade (QC) lasers is investigated, as a result of stimulated-optical-emission-assisted electron transport, the rate of which depends on the local photon density and is comparable to the longitudinal optical (LO) phonon scattering rate. A microscopic model based on rate equations is built to study the self-consistent process of interaction between local electrons and photons in QC lasers. The non-uniform distribution of lateral current and the corresponding spatial hole burning are simulated from this model. Moreover, multi-transverse-mode operation in QC lasers is also investigated. PMID:24663949

Huang, Xue; Dikmelik, Yamac; Gmachl, Claire

2014-03-10

380

An Improved Method of Manufacturing Corrugated Boxes: Lateral Corrugator  

SciTech Connect

Paper physicists have known that a corrugated box constructed from outer liner sheets having a predominant fiber orientation aligned with the corrugating flute direction would have higher stiffness and crush resistance (per unit of fiber weight) than the conventional box construction. Such increased performance per unit of fiber weight could result in fiber reduction and energy savings for boxes having equivalent performance specifications. The goal of this project was to develop and demonstrate a commercially viable lateral corrugating process. This included designing and building a pilot lateral corrugator, testing and evaluating pilot machine made boxes, and developing a strategy for commercialization.

Frank C. Murray Ph.D.; , Roman Popil Ph.D.; Michael Shaepe (formerly with IPST, now at Cargill. Inc)

2008-12-18

381

Missing upper lateral incisors: orthodontic considerations in young patients.  

PubMed

Missing lateral incisors are usually discovered by age 9 when general orthodontic treatment needs are becoming apparent. Whether to close, open or maintain a space for a missing lateral incisor is an orthodontic decision that needs to fit within a total plan of dental management. Factors to consider include:- Skeletal base relationship, severity of crowding, overjet, overbite, position into which the canine erupts, crown sizes, crown shapes, crown colours, gingival contours, gingival display on smiling, patient and parent attitude toward options, availability of appropriate prosthetic services, time delay before effecting "final" prosthetic treatment, space and bone required for implant fixtures and financial and biological costs. PMID:11709923

Wexler, G

2000-10-01

382

Painful Os Peroneum Syndrome Presenting as Lateral Plantar Foot Pain  

PubMed Central

Lateral plantar foot pain can be caused by various entities, and the painful os peroneum syndrome should be considered in the differential diagnosis. Recent developments in musculoskeletal ultrasonography are very useful for initial diagnosis. We discuss a 69-year-old female who experienced lateral plantar foot pain for over one month. Through physical examination, radiography, ultrasound and magnetic resonance imaging, she was diagnosed with the painful os peroneum syndrome with a chronic fatigue fracture of multipartite os peroneum and peroneus longus tenosynovitis, for which she underwent surgery. We herein report this rare condition and reviewed the relevant literature.

Oh, Seon Jeong; Kim, Young Hoon; Kim, Sun Ki

2012-01-01

383

Negative quantum capacitance in graphene nanoribbons with lateral gates  

NASA Astrophysics Data System (ADS)

We present numerical simulations of the capacitive coupling between graphene nanoribbons of various widths and gate electrodes in different configurations. We compare the influence of lateral metallic or graphene side gate structures on the overall back gate capacitive coupling. Most interestingly, we find a complex interplay between quantum capacitance effects in the graphene nanoribbon and the lateral graphene side gates, giving rise to an unconventional negative quantum capacitance. The emerging nonlinear capacitive couplings are investigated in detail. The experimentally relevant relative lever arm, the ratio between the coupling of the different gate structures, is discussed.

Reiter, R.; Derra, U.; Birner, S.; Terrés, B.; Libisch, F.; Burgdörfer, J.; Stampfer, C.

2014-03-01

384

Resume and analysis of NACA lateral control research  

NASA Technical Reports Server (NTRS)

An analysis of the principal results of recent NACA lateral control research is made by utilizing the experience and progress gained during the course of the investigation. Two things are considered of primary importance in judging the effectiveness of different control devices: the (calculated) banking and yawing motion of a typical small airplane caused by a deflection of the control, and the stick force required to produce this deflection. The report includes a table in which a number of different lateral control devices are compared on these bases.

Weick, Fred E; Jones, Robert T

1937-01-01

385

Lateral asymmetry of early seizure manifestations in experimental generalized epilepsy.  

PubMed

Reorganization of seizure networks during epileptogenesis involves cortico-subcortical and interhemispheric interactions. In the audiogenic kindling (AK) model of generalized tonic-clonic seizures, upstream seizure propagation along ascending brainstem-to-forebrain pathways determines progressive intensification of repeated sound-induced convulsions. Full-blown audiogenic seizures are bilaterally symmetric and their repetition results in bisynchronous recruiting the cortex in secondary epileptogenesis. The present study describes lateral asymmetry of initial behavioral and EEG manifestations of audiogenic seizures and AK in Wistar and WAG/Rij rats with acoustic hypersensitivity. These rats exhibit consistent individual lateralization of running seizures (run directionality) induced by repeated binaural stimulation. Since this initial preconvulsive running reflects seizure onset in the auditory brainstem, the running asymmetry suggests non-symmetric early epileptic activation of brainstem substrates by sound in these rats. Repetition of the asymmetric brainstem seizures led to asynchronous recruiting the cortex into seizure network and lateralization of running seizures was predictive for asymmetry of early cortical seizure manifestations in Wistar and WAG/Rij rats. Both electrographic markers of AK, spreading depression (SD) and post-running afterdischarge, first appeared in the cortex ipsilateral to run direction, suggesting lateralized brainstem-to-forebrain seizure generalization during AK. At the population level, no bias in lateralization of running and SD was found in Wistar and WAG/Rij rats but incidence of secondary cortical seizures varied, depending on strain and run laterality. Among Wistar rats, cortical seizures developed more rarely in right-runners than in left-runners, suggesting enhanced resistance of the right hemisphere to epileptogenesis in rats of this strain. WAG/Rij rats with mixed (absence and audiogenic) epilepsy showed weak lateralization of early cortical seizures and no left-right difference in their incidence during AK. Present findings suggest (1) lateralized brainstem-to-forebrain seizure propagation and hemispheric difference in its facility in Wistar rats, (2) alterations of intra- and interhemispheric seizure propagation in WAG/Rij rats with genetic absence epilepsy. PMID:22525136

Vinogradova, L V; Shatskova, A B

2012-06-28

386

Arthroscopic treatment for symptomatic discoid lateral meniscus during childhood  

Microsoft Academic Search

Purpose  The purpose of this study was to review the operative long-term results of a large cohort of children treated arthroscopically\\u000a for a symptomatic discoid lateral meniscus.\\u000a \\u000a \\u000a \\u000a \\u000a Methods  We retrospectively reviewed the arthroscopic procedures performed on 104 knees (97 patients) between 1990 and 2006 to treat\\u000a symptomatic discoid lateral meniscus in children. The median age at the time of surgery was 8 years

Stefano Stilli; Leonardo Marchesini Reggiani; Giulio Maria Marcheggiani Muccioli; Michela Cappella; Onofrio Donzelli

2011-01-01

387

Management of palato radicular groove in a maxillary lateral incisor  

PubMed Central

This study is to report the rare localization of a radicular groove on the palatal aspect of the maxillary lateral incisor and to discuss the pathology and management of the concomitant endo-periodontal defect. Unilateral palato-radicular groove was located on the Maxillary right lateral incisor of an 18-year-old female patient. The groove was associated with deep local periodontal pocket resulting in pulp necrosis and the formation of a large periapical lesion. A collaborative management was carried out using a combination of endodontic therapy, surgical enucleation, odontoplasty, and periodontal regenerative procedure resulting the successful healing of the periapical lesion.

Kishan, K. V.; Hegde, Vani; Ponnappa, K. C.; Girish, T. N.; Ponappa, M. C.

2014-01-01

388

Invariance of waveguide grating mirrors to lateral displacement phase shifts.  

PubMed

We present a method to analyze the coupling of lateral displacements in nanoscale structures, in particular waveguide grating mirrors (WGMs), into the phase of a reflected Gaussian beam using a finite-difference time-domain simulation. Such phase noise is of interest for using WGMs in high-precision interferometry. We show that, to the precision of our simulations (10(-7) rad), waveguide mirrors do not couple lateral displacement into phase noise of a reflected beam and that WGMs are therefore not subject to the same stringent alignment requirements as previously proposed layouts using diffraction gratings. PMID:23722763

Brown, Daniel; Friedrich, Daniel; Brückner, Frank; Carbone, Ludovico; Schnabel, Roman; Freise, Andreas

2013-06-01

389

Lateral retinaculum release in adolescent patellofemoral disorders: its relationship to peripheral nerve injury in the lateral retinaculum.  

PubMed

Adolescent patellofemoral disorders which are associated with recognizable change in the articular cartilage of the patella are called chondromalacia patellae. This is a clinical syndrome characterized by persistent retropatellar pain, but not always associated with histopathological changes of the articular cartilage. When lateral retinacular release is performed in such patients, pain is frequently eased even though lateral release does not always cause an appreciable change in patellofemoral contact pressure. This suggests that pain, at times, may emanate from the peripatellar retinacular supports themselves. Thirty-five knees of 22 patients suffering from anterior knee pain (with or without an unstable patella) were investigated histologically. Pathological changes in nerves were graded on a 0 to 3 + scale of severity. There was severe degenerative neuropathy in nine knees, moderate change in nine, and slight change in 11; the remaining six knees were normal. Histological investigation of the resected lateral retinaculum suggested that pain originated in the lateral retinaculum in many patients, and that degenerative changes in the nerves of the lateral retinaculum may be an important cause of pain in patients with patellofemoral disorders. PMID:1666010

Mori, Y; Fujimoto, A; Okumo, H; Kuroki, Y

1991-01-01

390

Lateral flow microarrays: a novel platform for rapid nucleic acid detection based on miniaturized lateral flow chromatography  

PubMed Central

Widely used nucleic acid assays are poorly suited for field deployment where access to laboratory instrumentation is limited or unavailable. The need for field deployable nucleic acid detection demands inexpensive, facile systems without sacrificing information capacity or sensitivity. Here we describe a novel microarray platform capable of rapid, sensitive nucleic acid detection without specialized instrumentation. The approach is based on a miniaturized lateral flow device that makes use of hybridization-mediated target capture. The miniaturization of lateral flow nucleic acid detection provides multiple advantages over traditional lateral flow devices. Ten-microliter sample volumes reduce reagent consumption and yield analyte detection times, excluding sample preparation and amplification, of <120?s while providing sub-femtomole sensitivity. Moreover, the use of microarray technology increases the potential information capacity of lateral flow. Coupled with a hybridization-based detection scheme, the lateral flow microarray (LFM) enables sequence-specific detection, opening the door to highly multiplexed implementations for broad-range assays well suited for point-of-care and other field applications. The LFM system is demonstrated using an isothermal amplification strategy for detection of Bacillus anthracis, the etiologic agent of anthrax. RNA from as few as two B. anthracis cells was detected without thermocycling hardware or fluorescence detection systems.

Carter, Darren J.; Cary, R. Bruce

2007-01-01

391

Intubating laryngeal mask airway as an independent ventilatory and intubation device. A comparison between supine, right lateral and left lateral  

PubMed Central

Background Sudden loss of airway in patients in the lateral position has always been proven to be difficult to manage with conventional laryngoscopy. We performed a randomized controlled trial to prove the success rate of ventilation and intubation in the lateral position via intubating laryngeal mask airway (ILMA). Methods Ninety patients were divided into three groups of 30 patients each, positioned supine, right lateral, and left lateral randomly. Each group comprised of both sexes of American Society of Anesthesiologists grade I and II, aged between 18-55 years with normal airway posted for surgery under general anesthesia. Patients were pre-medicated with fentanyl followed by induction with propofol and neuromuscular blockade with rocuronium. ILMA was inserted and blind tracheal intubation via ILMA was done. The success rate, time taken and the number of adjusting maneuvers used for both procedures were recorded. The data was tabulated and analyzed using ANOVA (analysis of variance), multiple 't' test and chi square. Results The success rate of intubation (96%) and time taken in insertion and intubation was found to be quite similar in all the three groups. Conclusions We conclude that the ILMA has an important role to play in the emergency management of airways in patients in the lateral position in terms of ease, success rate and time taken.

Bharadwaj, Avnish; Chauhan, Gaurav; Kalita, Drubajyoti

2013-01-01

392

Ligand-dependent Notch signaling strength orchestrates lateral induction and lateral inhibition in the developing inner ear.  

PubMed

During inner ear development, Notch exhibits two modes of operation: lateral induction, which is associated with prosensory specification, and lateral inhibition, which is involved in hair cell determination. These mechanisms depend respectively on two different ligands, jagged 1 (Jag1) and delta 1 (Dl1), that rely on a common signaling cascade initiated after Notch activation. In the chicken otocyst, expression of Jag1 and the Notch target Hey1 correlates well with lateral induction, whereas both Jag1 and Dl1 are expressed during lateral inhibition, as are Notch targets Hey1 and Hes5. Here, we show that Jag1 drives lower levels of Notch activity than Dl1, which results in the differential expression of Hey1 and Hes5. In addition, Jag1 interferes with the ability of Dl1 to elicit high levels of Notch activity. Modeling the sensory epithelium when the two ligands are expressed together shows that ligand regulation, differential signaling strength and ligand competition are crucial to allow the two modes of operation and for establishing the alternate pattern of hair cells and supporting cells. Jag1, while driving lateral induction on its own, facilitates patterning by lateral inhibition in the presence of Dl1. This novel behavior emerges from Jag1 acting as a competitive inhibitor of Dl1 for Notch signaling. Both modeling and experiments show that hair cell patterning is very robust. The model suggests that autoactivation of proneural factor Atoh1, upstream of Dl1, is a fundamental component for robustness. The results stress the importance of the levels of Notch signaling and ligand competition for Notch function. PMID:24821984

Petrovic, Jelena; Formosa-Jordan, Pau; Luna-Escalante, Juan C; Abelló, Gina; Ibañes, Marta; Neves, Joana; Giraldez, Fernando

2014-06-01

393

40 CFR 86.410-90 - Emission standards for 1990 and later model year motorcycles.  

Code of Federal Regulations, 2013 CFR

...Emission standards for 1990 and later model year motorcycles. 86.410-90 ...Emission standards for 1990 and later model year motorcycles. (a)(1) Exhaust emissions from 1990 and later model year gasoline-fueled, natural...

2013-07-01

394

38 CFR 3.318 - Presumptive service connection for amyotrophic lateral sclerosis.  

Code of Federal Regulations, 2010 CFR

...service connection for amyotrophic lateral sclerosis. 3.318 Section...service connection for amyotrophic lateral sclerosis. (a) Except as provided...section, the development of amyotrophic lateral sclerosis manifested at any...

2010-07-01

395

38 CFR 3.318 - Presumptive service connection for amyotrophic lateral sclerosis.  

Code of Federal Regulations, 2010 CFR

...service connection for amyotrophic lateral sclerosis. 3.318 Section...service connection for amyotrophic lateral sclerosis. (a) Except as provided...section, the development of amyotrophic lateral sclerosis manifested at any...

2009-07-01

396

Safety and the anatomy of the retroperitoneal lateral corridor with respect to the minimally invasive lateral lumbar intervertebral fusion approach.  

PubMed

Safe and reproducible outcomes of the lateral lumbar intervertebral fusion (LLIF) procedure rely on meticulous care and understanding of the anatomy of the lateral corridor. This review aims to describe the different important anatomic considerations when performing LLIF and offer technical notes that may help increase the safety of this procedure. The LLIF procedure is divided into 5 stages: patient positioning, abdominal wall dissection, retroperitoneal space dissection, deployment of the surgical retractors, and diskectomy. Each stage is preformed in a distinct anatomic compartment that may cause different typical complications. PMID:24703441

Regev, Gilad J; Kim, Choll W

2014-04-01

397

Dual-axis, Duo-lateral Position Sensitive Detectors  

Microsoft Academic Search

Over the years, a variety of approaches have been used to determine the position of a particle measured by a silicon detector. Discrete detectors require many channels of electronics to achieve good position resolution. Another avenue is to use a resistive detector, which measures the position by charge splitting. Resistive tetra-lateral detectors can be used to achieve both horizontal and

Robin Dienhoffer; Sherry Yennello

2007-01-01

398

Tuning the lateral mobility of thin block copolymer films  

NASA Astrophysics Data System (ADS)

Polymer mobility in confined environments is of both theoretical and practical interest. The controlled formation and characterization of systems where such effects can be studied remain active areas of investigation. In this work, we created ultrathin (< 50 nm) supported films of amphiphilic polybutylene-poly(ethylene) oxide diblock copolymers, through Langmuir-Blodgett and Langmuir-Schaefer techniques. To adjust the lateral mobility of these ultrathin films, short polyisobutylene homopolymer was introduced during the film assembly process. Preliminary fluorescence recovery after photobleaching (FRAP) results show that the lateral mobility of the block copolymers is proportional to the logarithm of homopolymer concentration. The mobility can be varied by up to a factor of 8 with as little as 1 mol% of homopolymer. The role of the added homopolymer on the block copolymer lateral mobility is likely to be related with several features such as chain entanglements, interfacial constraints, and interlayer friction. By varying the concentration and the molecular weight of the homopolymer introduced into the films, we attempt to explain the underlying physical mechanisms that are responsible for changes in lateral mobility.

Bermudez, Harry; Kourouklis, Andreas

2013-03-01

399

Early Math Matters: Kindergarten Number Competence and Later Mathematics Outcomes  

ERIC Educational Resources Information Center

Children's number competencies over 6 time points, from the beginning of kindergarten to the middle of 1st grade, were examined in relation to their mathematics achievement over 5 later time points, from the end of 1st grade to the end of 3rd grade. The relation between early number competence and mathematics achievement was strong and significant…

Jordan, Nancy C.; Kaplan, David; Ramineni, Chaitanya; Locuniak, Maria N.

2009-01-01

400

Efferent neurotransmission of circadian rhythms in Limulus lateral eye  

Microsoft Academic Search

We investigated efferent neurotransmission in theLimulus lateral eye by studying the action of pharmacological agents on responses of photoreceptor cells in vitro. We recorded transmembrane potentials from single cells in slices of retina that were excised during the day and maintained for several days in a culture medium. Potentials recorded in the absence of pharmacological agents resemble those recorded from

Leonard Kass; Janice L. Pelletier; George H. Renninger; Robert B. Barlow

1988-01-01

401

Beyond Subjection: Notes on the Later Foucault and Education  

ERIC Educational Resources Information Center

This article argues against the doxa that Foucault's analysis of education inevitably undermines self-originating ethical intention on the part of teachers or students. By attending to Foucault's lesser known, later work--in particular, the notion of "biopower" and the deepened level of materiality it entails--the article shows how the earlier…

Leask, Ian

2012-01-01

402

Lateral vibration: the key to BHA failure analysis  

SciTech Connect

Axial and torsional vibration analysis of three bottomhole assemblies was unable to identify the cause of repeated washouts and twistoffs. Finite element analysis, involving the six degrees of freedom available to the BHA and taking into account wellbore trajectory, WOB and other variables, established lateral vibrations as the probable culprit. Failures occurred when operating at speeds and in the drillstring locations predicted.

Mitchell, R.F.; Allen, M.B.

1985-03-01

403

Lateral-field-excited thin-film Lamb wave resonator  

NASA Astrophysics Data System (ADS)

The basic principles and technology for the development of lateral-field-excited Lamb acoustic wave resonators on sputter-deposited c-oriented thin aluminum nitride films are presented. The experimental results demonstrate that Lamb waves can be successfully used as an alternative to high-velocity surface acoustic waves.

Bjurström, Johan; Katardjiev, Ilia; Yantchev, Ventsislav

2005-04-01

404

S-Nitrosothiol Depletion in Amyotrophic Lateral Sclerosis  

Microsoft Academic Search

Recent data suggest that either excessive or deficient levels of protein S-nitrosylation may contribute to disease. Disruption of S-nitrosothiol (SNO) homeostasis may result not only from altered nitric oxide (NO) synthase activity but also from alterations in the activity of denitrosylases that remove NO groups. A subset of patients with familial amyotrophic lateral sclerosis (ALS) have mutations in superoxide dismutase

Christopher M. Schonhoff; Masaaki Matsuoka; Hemachand Tummala; Michael A. Johnson; Alvaro G. Estevéz; Rui Wu; Andrés Kamaid; Karina C. Ricart; Yuichi Hashimoto; Benjamin Gaston; Timothy L. Macdonald; Zuoshang Xu; Joan B. Mannick

2006-01-01

405

S-nitrosothiol depletion in amyotrophic lateral sclerosis  

Microsoft Academic Search

Recent data suggest that either excessive or deficient levels of protein S-nitrosylation may contribute to disease. Disruption of S-nitrosothiol (SNO) homeostasis may result not only from altered nitric oxide (NO) synthase activity but also from alterations in the activity of denitrosylases that remove NO groups. A subset of patients with familial amyotrophic lateral sclerosis (ALS) have mutations in superoxide dismutase

Christopher M. Schonhoff; Masaaki Matsuoka; Hemachand Tummala; Michael A. Johnson; Alvaro G. Estevez; Rui Wu; Andras. Kamaid; Karina C. Ricart; Yuichi Hashimoto; Benjamin Gaston; Timothy L. MacDonald; Zuoshang Xu; Joan B. Mannick

2006-01-01

406

Epitaxial Lateral Overgrowth of II-VI Semiconductors.  

National Technical Information Service (NTIS)

Epitaxial lateral overgrowth of CdTe was carried out on Si and GaAs substrates. Perfectly selective epitaxial growth was demonstrated on CdTe/Si and GaAs substrates using Si3N4 as the mask material. Selective growth has been possible at T>5OO deg C and pr...

I. B. Bhat

2001-01-01

407

Preview Control for Vehicle Lateral Guidance in Highway Automation  

Microsoft Academic Search

Continuous deterministic preview control is applied to the vehicle lateral contol problem. It is shown that the preview control consists of a feedback term and two feedforward terms. If the preview control algorithm is applied on the FSLQ augmented system, the feedback term will be exactly the same as the FSLQ feedback control law. Therefore, the advantages of the FSLQ

Huei Peng; Masayoshi Tomizuka

1991-01-01

408

Laterally Loaded Piles and Computer Program COM624G.  

National Technical Information Service (NTIS)

When the soil immediately below the base of a structure will not provide adequate bearing capacity, piles can be used to transfer load from the structure to soil strata which can support the applied load. This report deals with analysis of the lateral int...

L. A. Cooley L. C. Reese N. Radhakrishnan

1984-01-01

409

Spatiotemporal Coupling of the Tongue in Amyotrophic Lateral Sclerosis  

ERIC Educational Resources Information Center

Purpose: The primary aim of the investigation was to identify deficits in spatiotemporal coupling between tongue regions in amyotrophic lateral sclerosis (ALS). The relations between disease-related changes in tongue movement patterns and speech intelligibility were also determined. Methods: The authors recorded word productions from 11…

Kuruvilla, Mili S.; Green, Jordan R.; Yunusova, Yana; Hanford, Kathy

2012-01-01

410

Immunocytochemical characterisation of the wall of the bovine lateral ventricle  

Microsoft Academic Search

The cytoarchitecture of the walls of the bovine lateral ventricles was investigated by the use of immunocytochemistry. We defined three types of walls. Type 1 lined regions of white matter and had ciliated cuboidal ependyma, a few subependymal cells and a narrow subjacent glial layer. Type 2 lined the striatum and possessed ependymal cells with conspicuous basal processes that extended through a

L. M. Rodríguez-Pérez; M. Pérez-Martín; A. J. Jiménez; P. Fernández-Llebrez

2003-01-01

411

Experimental Automatic Lateral Control System For An Automobile  

Microsoft Academic Search

This report summarizes an experimental effort in integrating and testing an automated vehicle lateral control system. The project, a cooperative effort between the California Partners for Advanced Transit and Highway ( PATH) Program and IMRA America, Inc., included a discrete roadway reference system, on-vehicle magnetic sensing system, a computer control system and a hydraulic actuator.

Huei Peng; Wei-bin Zhang; Alan Arai; Ye Lin; Thomas Hessburg; Peter Devlin; Masayoshi Tomizuka; Steven Shladover

1992-01-01

412

A Theoretical and Experimental Study on Vehicle Lateral Control  

Microsoft Academic Search

The results of an experimental work on the lateral control of a full-scaled vehicle are reported in this paper. Two control algorithms were tested, a simple PID controller to serve as the baseline, and an optimal preview controller, which was developed to improve the tracking performance, ride quality and robustness of the system. The theoretical development and the experimental setup

Huei Peng; Thomas Hessburg; Masayoshi Tomizuka; Wei-Bin Zhang; Ye Lin; Peter Devlin; Steven E. Shladover; Alan Arai

1992-01-01

413

Treatment for lateral epicondylitis: variables related to recovery  

Microsoft Academic Search

The purpose of this study was to determine the effectiveness of a treatment regime utilised for lateral epicondylitis that is designed to expedite return to activity and to identify variables related to treatment outcomes. Patients treated in a sports medicine clinic between 1978 and 1980 received, by mail, a brief questionnaire investigating the variables of the injuries and level of

S G Gerberich; J D Priest

1985-01-01

414

Lateral release of the patella: Indications and contraindications  

Microsoft Academic Search

Charts were reviewed on patients at the Salt Lake Knee and Sports Medicine Clinic who had had a lateral release of the patella. Patients were divided into two groups. Group I contained patients who were entirely satisfied with the procedure, and Group II included patients who were complete failures (defined as a need for further surgical procedures). In Group I,

Patricia A. Kolowich; Lonnie E. Paulos; Thomas D. Rosenberg; Steve Farnsworth

1990-01-01

415

Pressure ulcers and lateral rotation beds: A case study  

Microsoft Academic Search

During a 6-month period, the WOC nurses at a 500-bed medical treatment facility noticed the development of nosocomial pressure ulcers on the sacrum, occiput, and heel areas of patients who were placed on lateral rotation specialty beds because they had pulmonary disorders. Measures were taken to address the problem by repositioning the patients and through a staff education program. Repositioning

Teresa Russell; Angela Logsdon

2003-01-01

416

Lateral Subcutaneous Internal Sphincterotomy in Treatment of Anal Fissure  

Microsoft Academic Search

One hundred and three patients with anal fissures have been treated by lateral internal sphincterotomy performed by a subcutaneous myotomy technique, and 99 have been successfully followed up for from 3 to 24 months (mean 11 months). The operation was free from significant complications, apart from slight reactionary bleeding in one case and a perianal abscess in another. The fissure

D. C. Hoffmann; J. C. Goligher

1970-01-01

417

Future time perspective in later adulthood: Review and research directions  

Microsoft Academic Search

The degree of experimental and quantitative detail which can be imposed on older adults' temporal experiences remains a significant area for investigation. This paper surveys material related to this general area of study, taking primarily a psychological focus. Review of this literature suggests that while a basic future time orientation is not significantly affected in later life, older adults are

William Rakowski

1979-01-01

418

Lactate dyscrasia: a novel explanation for amyotrophic lateral sclerosis  

Microsoft Academic Search

Amyotrophic lateral sclerosis (ALS; Lou Gehrig's disease) is a progressive debilitating neurodegenerative disease with no cure. We propose a novel molecular model for the pathogenesis of ALS that involves an adenosine triphosphate (ATP)-dependent muscle neuronal lactate shuttle (MNLS) at the neuromuscular junction (NMJ) to regulate the flow of lactate from muscle to neurons and vice versa. Failure of the MNLS

Sivan Vadakkadath Meethala; Craig S. Atwood

2010-01-01

419

Current hypotheses for the underlying biology of amyotrophic lateral sclerosis  

Microsoft Academic Search

The mechanisms involved in selective motor neuron degeneration in amyotrophic lateral sclerosis remain unknown more than 135 years after the disease was first described. Although most cases have no known cause, mutations in the gene encoding Cu\\/Zn superoxide dismutase (SOD1) have been implicated in a fraction of familial cases of the disease. Transgenic mouse models with mutations in the SOD1

Jeffrey D. Rothstein

2009-01-01

420

Current-mode CMOS image sensor using lateral bipolar phototransistors  

Microsoft Academic Search

A current-mode image sensor has been designed using current mirrors with amplifying device ratios. Prototype sensors have been fabricated in a standard 0.18-?m CMOS technology. Image capture is demonstrated from two 70 × 48 pixel arrays, using photodiodes and lateral bipolar phototransistors as the photodetectors. The latter type displays a reduced fixed pattern noise, while linearity is similar to that

Ying Huang; Richard I. Hornsey

2003-01-01

421

Rasch Measurement in the Assessment of Amytrophic Lateral Sclerosis Patients.  

ERIC Educational Resources Information Center

Examined the sensitivity to change over time of the Amytrophic Lateral Sclerosis Assessment Questionnaire (ALSAQ-40; C. Jenkinson and others, 1999). Findings for 764 individuals show that the ALSAQ-40 is a valid and responsive disease-specific health-related quality of life instrument for studies of patients with motor neuron diseases. (SLD)

Norquist, Josephine M.; Fitzpatrick, Ray; Jenkinson, Crispin

2003-01-01

422

Amyotrophic Lateral Sclerosis: An Introduction to Psychosocial and Behavioral Adaptations.  

ERIC Educational Resources Information Center

Defines amyotrophic lateral sclerosis (ALS) as motor-neuron disease that is terminal. Discusses symptoms associated with ALS and identifies treatment options. Reviews psychological and behavioral adaptations in regard to ALS clients, their families, and professionals who work with them. Discusses support groups as method of reducing stress for ALS…

Hoffman, R. Leigh; Decker, Thomas W.

1993-01-01

423

Behavior of axially loaded pile group under lateral cyclic loading  

Microsoft Academic Search

In this paper, a hybrid boundary element technique is implemented to analyze behavior of axially loaded pile group under lateral cycling loading. Nonlinear material behavior of soil is introduced by a rational approximation to continuum with nonlinear interface springs along the piles. Linear beam column finite elements are used to model the piles. By enforcing displacement and equilibrium conditions at

S. Küçükarslan; P. K. Banerjee

2003-01-01

424

Dynamic Response of Laterally Loaded Pile Groups in Clay  

Microsoft Academic Search

The effects of pile spacing, number of piles and configuration on displacement and bending response of pile groups in clay under dynamic lateral loading have been investigated. The displacement response of pile group in clay is strongly nonlinear. Pile –soil-pile interaction is predominant for the groups with closer spacing and with more number of piles. Group interaction causes reduction in

S. S. Chandrasekaran; A. Boominathan; G. R. Dodagoudar

2012-01-01

425

Behavior of monopile foundations under cyclic lateral load  

Microsoft Academic Search

This paper describes the development and application of design charts for monopile foundations of offshore wind turbines in sandy soil under long-term cyclic lateral load. It outlines a numerical model, working with a numerical concept, which makes the calculation of accumulated displacements based on cyclic triaxial test results possible, and it describes important factors affecting the deformation response of a

Martin Achmus; Yu-Shu Kuo; Khalid Abdel-Rahman

2009-01-01

426

The Relationship Between Childhood Teasing and Later Interpersonal Functioning  

Microsoft Academic Search

The current study explored the relationship between recall of a form of bullying, specifically childhood teasing, and later interpersonal functioning in a sample of 414 college students. It was predicted that memories of frequent teasing during childhood would be associated with fewer close friends, a more anxious attachment style in the context of romantic relationships, and lower social self-esteem in

Deborah Roth Ledley; Eric A. Storch; Meredith E. Coles; Richard G. Heimberg; Jason Moser; Erica A. Bravata

2006-01-01

427

Gliding behaviour elicited by lateral looming stimuli in flying locusts  

Microsoft Academic Search

We challenged tethered, flying locusts with visual stimuli looming from the side towards one eye in a way that mimics the approach of a predatory bird. Locusts respond to the lateral approach of a looming object with steering movements and a stereotyped, rapid behaviour in which the wingbeat pattern ceases and the wings are swept into a gliding posture. This

Roger D. Santer; Peter J. Simmons; F. Claire Rind

2005-01-01

428

17. DETAIL OF LOWER CHORDS AND BOTTOM LATERAL BRACING OF ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

17. DETAIL OF LOWER CHORDS AND BOTTOM LATERAL BRACING OF WEST DECK TRUSS AND PIER NO. 2, FROM WEST RIVERBANK. VIEW TO EAST. - MacArthur Bridge, Spanning Mississippi River on Highway 34 between IA & IL, Burlington, Des Moines County, IA

429

A Lateral Transzygomatic-Transtemporal Approach to the Infratemporal Fossa  

PubMed Central

This report describes an alternative approach to the infratemporal fossa lesions through a lateral zygomato-temporal craniotemy, which modifies the extradural temporopolar technique for cavernous sinus surgery. First, an L-shaped osteotomy of the zygoma from the frontozygomatic suture attaching the zygomatre arch and low positioned temporal cramotomy are made. Through this zygomato-temporal craniotomy and orbitotemporal drilling, leaving the lateral orbital rim and orbital roof intact, skeletonization of the foramens rotundum and ovale are carried out. The key element of this infratemporal exposure is the dissection and mobilization of the trigeminal nerve, trigeminal second branch rostrally, and the third branch caudally, which facilitates a wide exposure of the infratemporal fossa with preserving trigeminal function. The corridor between the mobilized trigeminal branches provides direct access to the lateral and medial pterygoid plate, internal maxillary artery, sphenoid and maxillary sinuses, maxilla and, finally, the parapharyngeal area. Our experiences have demonstrated that this lateral transzygomatic-transtemporal exposure is satisfactory for use with infratemporal fossa tumors. This approach has an advantage for cranial-base exposure with decreased risks of cosmetic deformity and of trigeminal nerve dysfunction. ImagesFigure 2p279-bFigure 3Figure 4Figure 5Figure 6Figure 7Figure 8Figure 9p285-bFigure 10

Terasaka, Shunsuke; Sawamura, Yutaka; Goto, Shin; Fukushima, Takanori

1999-01-01

430

The normal angiographic sylvian point on the lateral cerebral angiogram  

Microsoft Academic Search

The angiographic sylvian point (ASP) is one of the most useful landmarks on cerebral angiograms for detecting retrosylvian masses. Although it is suggested to be the halfway point on the clinoparietal line (CPL), its exact normal position has not been defined. The lateral carotid angiograms of 100 consecutive patients from 22 to 65 years of age were used to study

S. H. Lee; H. I. Goldberg

1979-01-01

431

Symptoms Predictive for the Later Development of Retinal Breaks  

Microsoft Academic Search

Objective: To identify symptoms in patients with iso- lated posterior vitreous detachment predictive for the later development of retinal breaks. Methods: Two hundred eighty consecutive patients seen with symptoms of posterior vitreous detachment were prospectively asked to complete a questionnaire detail- ing their symptoms. At the time of presentation and fol- low-up, all patients had a full ophthalmologic examina- tion

Koen A. van Overdam; Marijke Wefers Bettink-Remeijer; Paul G. Mulder; Jan C. van Meurs

2001-01-01

432

Fighter aircraft lateral directional axes full envelope control law design  

Microsoft Academic Search

A decoupled wide envelope lateral\\/directional axes control design is presented for a supermanoeuvrable version of an F-18 aircraft. A control structure is developed that separates gain scheduling issues from aircraft performance issues. Flight condition dependent state and control effectiveness variations are accounted for by an inner loop controller designed using eigenstructure assignment. Structured singular value synthesis is used to design

ANDREW SPARKS; JAMES BUFFINGTON; SIVA BANDA

1994-01-01

433

The Relationship between Reading Ability and Lateralized Lexical Decision  

ERIC Educational Resources Information Center

Although lexical decision remains one of the most extensively studied cognitive tasks, very little is known about its relationship to broader linguistic performance such as reading ability. In a correlational study, several aspects of lateralized lexical decision performance were related to vocabulary and reading comprehension measures, as…

Weems, Scott A.; Zaidel, Eran

2004-01-01

434

The steady, inevitable decline of amyotrophic lateral sclerosis patients.  

PubMed

Progressive muscle weakness and fasciculations can indicate developing amyotrophic lateral sclerosis (ALS), also called Lou Gehrig's disease. Its treatment and prognosis have been unchanged for almost 100 years, although our understanding on a cellular level is better. All ALS patients can be expected to progress to a state that requires complete supportive care. PMID:16548670

Zanni, Guido R; Wick, Jeannette Y

2005-10-01

435

Lateral Epitaxial Overgrowth of GaN on Si(111).  

National Technical Information Service (NTIS)

The lateral epitaxial overgrowth of GaN on Si(111) substrates was achieved using an extension of our standard LEO process on GaN/Al2O3 substrates, and the reduction of the dislocation density was demonstrated by transmission electron microscopy (TEM) and ...

1998-01-01

436

Amyotrophic lateral sclerosis. A study of its presentation and prognosis  

Microsoft Academic Search

All identified Israeli patients with amyotrophic lateral sclerosis (ALS) with onset of the disease from 1959 through 1975 (n=318) were evaluated clinically. Most of our patients (63%) presented with weakness; only 10% presented with atrophy and 3% with fasciculations. In 31% of the cases, the onset of the disease was focal and 22% of the patients presented with bulbar signs,

Sasson S. Gubbay; Esther Kahana; Nelly Zilber; Gerald Cooper; Shy Pintov; Yaffa Leibowitz

1985-01-01

437

Electromyographic patterns of individuals suffering from lateral tennis elbow  

Microsoft Academic Search

This study investigated the applicability of using surface electromyography (EMG) as a tool for differentiating between persons suffering from lateral tennis elbow and the healthy age-matched adults. Temporal muscle activation patterns of the tennis elbow group were evaluated to determine if they varied between subject groups and if noted variations might be interpreted as arresting or exacerbating the injury. Sixteen

Jeffrey A. Bauer; Robert D. Murray

1999-01-01

438

Cyriax physiotherapy for tennis elbow\\/lateral epicondylitis  

Microsoft Academic Search

Tennis elbow or lateral epicondylitis is one of the most common lesions of the arm with a well defined clinical presentation, which significantly impacts on the community. Many treatment approaches have been proposed to manage this condition. One is Cyriax physiotherapy. The effectiveness and reported effects of this intervention are reviewed.

D Stasinopoulos; M I Johnson

2004-01-01

439

Styling in a Language Learned Later in Life  

ERIC Educational Resources Information Center

This article analyses the styles of English produced by an adult migrant who started to speak the language later in life, and it approaches them from the perspective of quantitative style-shifting and discursive stylization. After defining style and the procedures needed to justify the term "L2," the study describes the focal…

Rampton, Ben

2013-01-01

440

Synchrotron Radiation X Ray Topography Study of Lateral Field Resonators.  

National Technical Information Service (NTIS)

Using synchrotron radiation, plano-convex AT resonators excited by a lateral field were studied by the X-ray topography technique. Different overtones and anharmonics of the three types of the thickness modes were observed. The study showed that it is pos...

B. Capelle, J. Detaint, J. Schwartzel, Y. Zheng, A. Zarka

1992-01-01

441

SideWall Vertical Electrodes for Lateral Field Microfluidic Applications  

Microsoft Academic Search

This paper describes the design, fabrication, and testing of microfluidic devices enabled by electrodes embedded vertically in the side walls of SU-8 microchannels. With vertical electrodes on the side walls, one can generate higher lateral electrical fields uniform along the vertical direction in the channel (perpendicular to the substrate). By designing the electrode shapes and configurations, uniform and nonuniform electrical

Lisen Wang; Lisa Flanagan; Abraham P. Lee

2007-01-01

442

Unstable trochanteric fractures: the role of lateral wall reconstruction  

PubMed Central

The sliding compression device, a widely used implant in unstable proximal femoral fractures, suffers from two major limitations: excessive collapse and screw cut-out. Commonly attributed reasons for these are lateral wall comminution and single-point fixation, respectively. We report our experience of stabilising 74 unstable trochanteric fractures, of which 46 cases underwent lateral wall reconstruction using a trochanteric stabilising plate (TSP) in combination with a dynamic hip screw (DHS), and 34 cases with an intact lateral wall had a DHS with an additional anti-rotation screw providing two-point fixation. Fracture consolidation was observed in all cases at an average of 13.56 weeks. Overall functional hip score as per the Salvati and Wilson scoring system was >30 points in 55 patients. Lateral wall reconstruction is an important component in stabilisation of unstable trochanteric fractures and a combination of TSP with a DHS appears to be a useful device to achieve this. Addition of an antirotation screw is likely to enhance the stability further by providing two-point fixation.

Sangwan, Kapil; Kamboj, Pradeep; Punia, Sarabjeet S.; Walecha, Pankaj

2009-01-01

443

Lateral Symbiont Acquisition in a Maternally Transmitted Chemosynthetic Clam Endosymbiosis  

Microsoft Academic Search

Deep-sea clams of the family Vesicomyidae live in symbiosis with intracellular chemosynthetic bacteria. These symbionts are transmitted maternally (vertically) between host generations and should therefore show a pattern of genetic variation paralleling that of the cotransmitted host mitochondrion. However, instances of lateral (nonvertical) symbiont acquisition could still occur, thereby decoupling symbiont and mitochondrial phylogenies. Here, we provide the first evidence

Frank J. Stewart; Curtis R. Young; Colleen M. Cavanaugh

2008-01-01

444

Sources of Continuity in Infant Predictors of Later IQ.  

ERIC Educational Resources Information Center

Sources of continuity among nine measures of infant cognitive processing and later childhood intelligence quotient were examined through developmental structural equation models applied to a sample of 208 twin pairs measured from 7 to 36 months. Skills assessed appear related to general cognitive ability in a relatively unstable manner. (SLD)

Cardon, Lon R.; Fulker, David W.

1991-01-01

445

Using Monomolecular Films to Characterize Lipid Lateral Interactions  

PubMed Central

Summary Membrane lipids are structurally diverse in ways that far exceed the role envisioned by Singer and Nicholson of simply providing a fluid bilayer matrix in which proteins reside. Current models of lipid organization in membranes postulate that lipid structural diversity enables nonrandom lipid mixing in each leaflet of the bilayer, resulting in regions with special physical and functional properties, i.e., microdomains. Central to understanding the tendencies of membrane lipids to mix nonrandomly in biomembranes is the identification and evaluation of structural features that control membrane lipid lateral mixing interactions in simple model membranes. The surface balance provides a means to evaluate the lateral interactions among different lipids at a most fundamental level—mixed in binary/ternary combinations that self-assemble at the air–water interface as monomolecular films, i.e., monolayers. Analysis of surface pressure and interfacial potential as a function of average cross-sectional molecular area provide insights into hydrocarbon chain ordering, lateral compressibility/elasticity, and dipole effects under various conditions including those that approximate one leaflet of a bilayer. Although elegantly simple in principle, effective use of the surface balance requires proper attention to various experimental parameters, which are described herein. Adequate attention to these experimental parameters ensures that meaningful insights are obtained into the lipid lateral interactions and enables lipid monolayers to serve as a basic platform for use with other investigative approaches.

Brown, Rhoderick E.; Brockman, Howard L.

2008-01-01

446

Laterally stacked Schottky diodes for infrared sensor applications  

NASA Technical Reports Server (NTRS)

Laterally stacked Schottky diodes for infrared sensor applications are fabricated utilizing porous silicon having pores. A Schottky metal contract is formed in the pores, such as by electroplating. The sensors may be integrated with silicon circuits on the same chip with a high quantum efficiency, which is ideal for IR focal plane array applications due to uniformity and reproducibility.

Lin, True-Lon (inventor)

1991-01-01

447

Lateral diffusion in inhomogeneous membranes. Model membranes containing cholesterol.  

PubMed Central

The problem of lateral diffusion in inhomogeneous membranes is illustrated by a theoretical calculation of the lateral diffusion of a fluorescent lipid probe in binary mixtures of phosphatidylcholine and cholesterol under conditions of temperature and composition such that this lipid mixture consists of alternating parallel domains of fluid and solid lipid, having separations that are small compared with the distance scale employed in photobleaching experiments. The theoretical calculations clearly illustrate how inhomogeneities in membrane composition affecting the lateral motion of membrane components on a small (10-100 nm) distance scale can give complex diffusive responses in experiments such as fluorescence photobleaching that employ comparatively macroscopic distances (10-100 micrometers) for the measurement of diffusive recovery. The theoretical calculations exhibit the unusual dependence of the apparent lateral diffusion coefficient of a fluorescent lipid probe on lipid composition in binary mixtures of cholesterol and phosphatidylcholines as reported by Rubenstein et al. (1979, Proc. Natl. Acad. Sci. U.S.A., 76:15-18).

Owicki, J C; McConnell, H M

1980-01-01

448

Unclamped inductive switching dynamics in lateral and vertical power DMOSFETs  

Microsoft Academic Search

Unclamped inductive switching (UIS) is a routine method for characterizing the ruggedness of a device in the industry. Using this method, comparison of the ruggedness of a vertical DMOS and a lateral DMOS is presented in this paper. A complete understanding of the dynamics in each of the devices under UIS conditions is achieved by comparing the results obtained through

K. Chinnaswamy; P. Khandelwal; M. Trivedi; K. Shenai

1999-01-01

449

13. ONE OF TWO LATERAL ROOF TRUSSES AND ROOF SUPPORT ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

13. ONE OF TWO LATERAL ROOF TRUSSES AND ROOF SUPPORT BEAMS OF SARATOGA GAS LIGHT COMPANY GASHOLDER NO. 2 HOUSE LOOKING WEST. THE WIRES AND BEAM AT RIGHT CENTER OF PHOTOGRAPH HAVE BEEN ADDED TO STABILIZE TRUSS SYSTEM - Saratoga Gas Light Company, Gasholder No. 2, Niagara Mohawk Power Corporation Substation Facility, intersection of Excelsior & East Avenues, Saratoga Springs, Saratoga County, NY

450

Laparoscopy versus open left lateral segmentectomy for recurrent pyogenic cholangitis  

Microsoft Academic Search

Background: Recurrent pyogenic cholangitis (RPC) is a common disease in Southeast Asia. Its classical presentation is repeated attacks of cholangitis with multiple recurrences of bile duct stones. The stones are commonly located in the left lateral segments (2 and 3) and therefore complete clearance is difficult to achieve by either endoscopic retrograde cholangiopancreatography or surgical exploration of the common bile

C. N. Tang; C. K. Tai; J. P. Y. Ha; W. T. Siu; K. K. Tsui; M. K. W. Li

2005-01-01

451

Ratchet effects in graphene and quantum wells with lateral superlattice  

NASA Astrophysics Data System (ADS)

Theoretical and experimental studies on the ratchet effects in graphene and in quantum wells with a lateral superlattice excited by alternating electric fields of terahertz frequency range are presented. We discuss the Seebeck ratchet effect and helicity driven photocurrents and show that the photocurrent generation is based on the combined action of a spatially periodic in-plane potential and a spatially modulated light.

Golub, L. E.; Nalitov, A. V.; Ivchenko, E. L.; Olbrich, P.; Kamann, J.; Eroms, J.; Weiss, D.; Ganichev, S. D.

2013-12-01

452

Modeling, Simulation, and Parameter Estimation of Lateral Spacecraft Fuel Slosh  

NASA Technical Reports Server (NTRS)

Predicting the effect of fuel slosh on a spacecraft and/or launch vehicle attitude control system is a very important and a challenging task. Whether the spacecraft is under spinning or lateral moving conditions, the dynamic effect of the fuel slosh will help determine whether the spacecraft will remain on its chosen trajectory. There are three categories of slosh that can be caused by launch vehicle and/or spacecraft maneuvers when the fuel is in the presence of an acceleration field. These include bulk fluid motion, subsurface wave motion, and free surface slosh. Each of these slosh types have a periodic component that is defined by either a spinning or lateral motion. For spinning spacecraft, all three types of slosh can play a major role in determining stability. Bulk fluid motion and free surface slosh can affect the lateral slosh characteristics. For either condition, the possibility for an unpredicted coupled resonance between the spacecraft and its on board fuel can have mission threatening affects. This on-going research effort aims at improving the accuracy and efficiency of modeling techniques used to predict these types of lateral fluid motions. In particular, efforts will focus on analyzing the effects of viscoelastic diaphragms on slosh dynamics.

Chatman, Yadira; Gangadharan, Sathya; Marsell, Brandon; Schlee, Keith; Sudermann, James; Walker, Charles; Ristow, James

2008-01-01

453

[A case of lateral cleft lip. Embryology and surgical technic].  

PubMed

Lateral labial cleft is exceptionally rare. This malformation gives the opportunity to evaluate its origin (following the embryology of facial segments) and its association with other deformities. Surgical treatment must reconstruct an anatomic and functional situation which must give a good aestetic result. PMID:6533594

Tamisani, A; Di Noto, C; Müller, L; Giorgini, F

1984-01-01

454

Acoustic Investigations into the Later Acquisition of Syllabic "-es" Plurals  

ERIC Educational Resources Information Center

Purpose: Children acquire /-ez/ syllabic plurals (e.g., buses) later than /-s, -z/ segmental plurals (e.g., cats,dogs). In this study, the authors explored whether increased syllable number or segmental factors best explains poorer performance with syllabic plurals. Method: An elicited imitation experiment was conducted with 14 two-year-olds…

Mealings, Kiri T.; Cox. Felicity; Demuth, Katherine

2013-01-01

455

[Lateral mechanics of muscle fibres and its role in signaling].  

PubMed

Different aspects of the lateral mechanics of muscle fibres have been considered. The current data on the transverse stiffness of intact muscle cells, demenbranized muscle fibres, and isolated myofibrils under various conditions and at different stages of the differentiation of myofibers. The signaling role of cytoskeleton proteins and possible mechanisms of their involvement in the structural basis of transverse stiffness are dissussed. PMID:19569516

Ogneva, I V; Lebedev, D V; Shenkman, B S

2009-01-01

456

Childhood Malnutrition Linked to High Blood Pressure Later in Life  

MedlinePLUS

... page, please enable JavaScript. Childhood Malnutrition Linked to High Blood Pressure Later in Life: Study Preventing childhood hunger might ... June 30, 2014 Related MedlinePlus Pages Child Nutrition High Blood Pressure Malnutrition MONDAY, June 30, 2014 (HealthDay News) -- Young ...

457

Lateral collapse of composite cylindrical tubes between flat platens  

Microsoft Academic Search

A detailed experimental investigation of the quasi-static lateral crushing of composite cylindrical tubes between flat platens has been carried out. Tubes employed were made of glass fibre reinforced with epoxy and their diameter to thickness ratio varied from 7.33 to 39. Typical histories of their deformation are presented. Behaviour of tubes as regards the peak crushing load, post collapse load,

N. K Gupta; H Abbas

2000-01-01

458

Later Leaders in Education: Jennie Wahlert. Woman of Achievement.  

ERIC Educational Resources Information Center

Presents a short biography of Jennie Wahlert, who taught in the St. Louis Public Schools in the early 1900s, and later served in supervisory positions in the schools and as a college professor. Her career spanned seven decades and had a significant influence on education in St. Louis. (MDM)

Meyer, Alberta L.

1993-01-01

459

Statistical thermodynamics of adsorbates with nonsymmetrical lateral interactions  

Microsoft Academic Search

The exact adsorption thermodynamics of particles with nonsymmetrical ad-ad interactions on a one-dimensional space is presented. The asymmetry is introduced by considering the lateral interactions depending on the orientation of the adsorbed molecules. The adsorption process is monitored by following the adsorption isotherm, the thermodynamic factor, the differential heat of adsorption, and the configurational entropy of the adlayer. A rich

F. Romá; A. J. Ramirez-Pastor

2004-01-01

460

Designing a metallic nanoconcentrator for a lateral multijunction photovoltaic cell  

Microsoft Academic Search

A lateral multijunction photovoltaic (PV) concept is introduced that explores the unique ability of plasmonic nanoantennas to locally concentrate optical energy and spectrally filter incoming light at the subwavelength level. This electromagnetic field enhancement near the localized plasmon resonance modes of the metallic nanoantennas can be used to selectively increase light absorption in semiconductor nanowires at specific spectral and spatial

Trudie Wang; Peter Peumans

2011-01-01

461

Identification of Lateral Dynamics and Parameter Estimation of Heavy Vehicles  

NASA Astrophysics Data System (ADS)

A system identification technique is applied to determine the lateral dynamics of an articulated freight vehicle subject to three different steering excitations and levels of measurement noise. An algorithm is proposed to extract an estimate of significant vehicle parameters considered to be uncertain. In addition to the commonly used ramp step (RS) and quasi-impulse (QI) steering inputs, a pseudo-random binary sequence (PRBS) excitation signal is proposed to stimulate all the important modes associated with the lateral directional dynamics of the vehicle. It is concluded that the vehicle transfer function can be characterised accurately under PRBS and QI excitations, and the signal-to-noise ratios superior to 20 dB. The low-order dynamics can be identified further under higher measurement noise levels. The proposed algorithm yields an accurate and robust estimate of uncertain vehicle parameters irrespective of the starting estimates and excitation signals. The algorithm provides the most effective estimates of the parameters to which lateral dynamics is most sensitive. The robustness of the proposed method is examined further using the data generated from a comprehensive yaw/roll non-linear model. From the results it is concluded that the directional dynamics of the vehicle is influenced mostly by the lateral and yaw dynamics, while the contributions due to roll dynamics are relatively small.

Yang, X.; Rakheja, S.; Stiharu, I.

1998-09-01

462

Incidence of amyotrophic lateral sclerosis in Rhineland-Palatinate, Germany.  

PubMed

Abstract There is a lack of prospective and population based epidemiological data on amyotrophic lateral sclerosis in Germany to date. The ALS registry Rhineland-Palatinate was established to investigate the incidence, course and phenotypic variety of ALS in this south-west German state of about 4 million inhabitants. During the period 2010-2011, consecutive incident patients with amyotrophic lateral sclerosis according to the revised El Escorial criteria were included and followed up using multiple overlapping sources of case ascertainment. One hundred and forty-six patients were enrolled. The annual crude incidence for amyotrophic lateral sclerosis in Rhineland-Palatinate was 1.8/100,000 person-years (95% CI 1.6-2.2). Male to female ratio was 1.1:1. Incidence increased with age reaching a peak in the 70-74 years age group and declined thereafter. Late-onset ALS (? 75 years) was found in 14.4% of patients. About 32% of patients presented with bulbar onset. In conclusion, incidence rate of amyotrophic lateral sclerosis in Rhineland-Palatinate is within the range of other prospective population based registers in Europe and North America. Gender ratio is nearly balanced. PMID:24571628

Wolf, Joachim; Wöhrle, Johannes C; Palm, Frederick; Nix, Wilfred A; Maschke, Matthias; Safer, Anton; Becher, Heiko; Grau, Armin J

2014-06-01

463

Amyotrophic Lateral Sclerosis Patients' Perspectives on Use of Mechanical Ventilation.  

ERIC Educational Resources Information Center

Interviewed 13 amyotrophic lateral sclerosis patients. All believed that they alone should make decision regarding use of mechanical ventilation. Factors they considered important were quality of life, severity of disability, availability of ventilation by means of nasal mask, possible admission to long-term care facility, ability to discontinue…

Young, Jenny M.; And Others

1994-01-01

464

Resting Anal Pressure Following Hemorrhoidectomy and Lateral Sphincterotomy  

Microsoft Academic Search

PURPOSE: The role of high anal pressure in the pathophysiology of hemorrhoids and anal fissures is debated. We compared resting anal pressures following left lateral sphincterotomy and hemorrhoidectomy in a prospective manometric study with emphasis on the recovery of the internal anal sphincter activity. METHODS: Included in the study were 38 patients with third-degree or fourth-degree symptomatic hemorrhoids who underwent

Dan Alper; Edward Ram; Gideon Y. Stein; Zeev Dreznik

2005-01-01

465

Lateral internal sphincterotomy for fissure-in-ano—Revisited  

Microsoft Academic Search

PURPOSE: A disturbing complication rate following lateral internal sphincterotomy (LIS) has recently been reported, and this study assessed our complication rate. METHODS: Charts of 312 patients who were operated on between January 1975 and December 1993 were reviewed. RESULTS: There were 148 men (47.5 percent) and 164 women (52.5 percent), ranging in age from 16 to 95 (mean, 40) years.

Nissim Hananel; Philip H. Gordon

1997-01-01

466

Anal endosonographic evaluation after closed lateral subcutaneous sphincterotomy  

Microsoft Academic Search

PURPOSE: The present study was undertaken to evaluate anal endosonographic results of the transverse and longitudinal extent of internal anal sphincter division after closed lateral subcutaneous sphincterotomy and its relationship to outcome with respect to anal fissure recurrence and postoperative anal incontinence. METHODS: Ten patients selected for symptomatic anal fissure recurrence (mean follow-up, 10.9 months) and 41 asymptomatic control patients

E. García-Granero; A. Sanahuja; J. García-Armengol; E. Jiménez; P. Esclapez; M. Mínguez; A. Espí; F. López; S. Lledó

1998-01-01

467

Lateral internal sphincterotomy under local anesthesia (randomized clinical trial)  

Microsoft Academic Search

Summary  BACKGROUND: Today there is an attempt to perform Lateral Internal Sphincterotomy (LIS) operation on an ambulatory basis under local anesthesia. This study aimed to compare postoperative outcome in local anesthesia with spinal anesthesia. METHODS: Design: randomized, double blinded, controlled trial. 62 patients were randomly divided into group A (local anesthesia) and group B (spinal anesthesia) with n = 31 equally.

S. Mohsen Towliat Kashani; Mohebi Hasan Ali; Lak Marzie; Ziaee S. Ali

2006-01-01

468

Glyceryl trinitrate vs. lateral sphincterotomy for chronic anal fissure  

Microsoft Academic Search

INTRODUCTION: Glyceryl trinitrate has been shown to be an effective treatment for chronic anal fissure. It decreases anal tone and ultimately heals anal fissures. The aim of this trial was to compare glyceryl trinitrate with lateral sphincterotomy (current standard treatment) as definitive management for chronic anal fissure. METHODS: All patients with symptoms of chronic anal fissure were randomly assigned to

Justin Evans; Andrew Luck; Peter Hewett

2001-01-01

469

Simultaneous Identification of Duplications and Lateral Gene Transfers  

Microsoft Academic Search

The incongruency between a gene tree and a corresponding species tree can be attributed to evolutionary events such as gene duplication and gene loss. This paper describes a combinatorial model where so-called DTL-scenarios are used to explain the differences between a gene tree and a corresponding species tree taking into account gene duplications, gene losses, and lateral gene transfers (also

Ali Tofigh; Michael T. Hallett; Jens Lagergren

2011-01-01

470

12. SOUTHWEST VIEW OF FIRST CENTRE FAMILY DWELLING HOUSE, LATER ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

12. SOUTHWEST VIEW OF FIRST CENTRE FAMILY DWELLING HOUSE, LATER FARMER DEACON'S SHOP, WITH SECOND CENTRE FAMILY DWELLING HOUSE IN BACKGROUND - Shaker Centre Family Dwelling House (First), North side of Village Road, North of U.S. Route 68 & State Route 33 intersection, Shakertown, Mercer County, KY

471

Prenatal Human Lateral Geniculate Nucleus: A Quantitative Light Microscopic Study  

Microsoft Academic Search

Using morphometric methods, a quantitative study has been carried out on the lateral geniculate nucleus (LGN) of human fetuses ranging in gestational age from 13 to 38 weeks. The volume of the nucleus as well as the neuronal, glial and dead cell populations have been studied in Nissl preparations. While the volume of the LGN shows a progressive increase throughout

Aijaz A. Khan; Shashi Wadhwa; R. M. Pandey; Veena Bijlani

1993-01-01

472

Transitions into and out of Cohabitation in Later Life  

ERIC Educational Resources Information Center

Cohabitation among adults over age 50 is rising rapidly, more than doubling from 1.2 million in 2000 to 2.75 million in 2010. A small literature provides a descriptive portrait of older cohabitors, but no study has investigated transitions into and out of cohabitation during later life. Drawing on demographic and life course perspectives, the…

Brown, Susan L.; Bulanda, Jennifer Roebuck; Lee, Gary R.

2012-01-01

473

The Effects of Bilateral Presentations on Lateralized Lexical Decision  

ERIC Educational Resources Information Center

We investigated how lateralized lexical decision is affected by the presence of distractors in the visual hemifield contralateral to the target. The study had three goals: first, to determine how the presence of a distractor (either a word or a pseudoword) affects visual field differences in the processing of the target; second, to identify the…

Fernandino, Leonardo; Iacoboni, Marco; Zaidel, Eran

2007-01-01

474

Language: A Partial Link between Infant Attention and Later Intelligence.  

ERIC Educational Resources Information Center

This study assessed children's visual recognition memory at seven months; their language development up to four years; and their intelligence up to five years. A greater preference for novelty in infancy was associated with later comprehension and expressive language and higher IQ scores. The relationship between novelty preference and IQ was…

Rose, Susan A.; And Others

1991-01-01

475

Surface accumulated lateral npn BJT's characteristics in SOI NMOSFETs  

Microsoft Academic Search

Lateral npn bipolar junction transistors (BJTs) in SOI MOSFET structures are investigated under various gate voltages. Negative resistance caused by base resistance modulation is observed. The surface-accumulated BJT mode is superior to the MOSFET mode in transconductance-to-current ratio and output resistance. Scaling properties are also discussed together with the need for a P+ polysilicon gate

Youn-Jae Kook; Jong-Ho Lee; Young-June Park; Hong-Shick Min

1999-01-01

476

Asymptotics of bound state for laterally coupled waveguides  

Microsoft Academic Search

A system of two waveguides coupled laterally through small windows is considered. The asymptotics (in the width of windows) of an eigenvalue close to the threshold are obtained. The cases of one and several coupling windows are studied. The technique is that of matching the asymptotic expansions of the solutions.

I. Yu Popov

1999-01-01

477

The lateral occipital complex and its role in object recognition  

Microsoft Academic Search

Here we review recent findings that reveal the functional properties of extra-striate regions in the human visual cortex that are involved in the representation and perception of objects. We characterize both the invariant and non-invariant properties of these regions and we discuss the correlation between activation of these regions and recognition. Overall, these results indicate that the lateral occipital complex

Kalanit Grill-Spector; Zoe Kourtzi; Nancy Kanwisher

2001-01-01

478

Network Type and Mortality Risk in Later Life  

ERIC Educational Resources Information Center

Purpose: The purpose of this study was to examine the association of baseline network type and 7-year mortality risk in later life. Design and Methods: We executed secondary analysis of all-cause mortality in Israel using data from a 1997 national survey of adults aged 60 and older (N = 5,055) that was linked to records from the National Death…

Litwin, Howard; Shiovitz-Ezra, Sharon

2006-01-01

479

Lateral force transmission across costameres in skeletal muscle.  

PubMed

In skeletal muscle, contractile force can be transmitted laterally between the z-disks and M-lines of neighboring myofibrils, across the sarcolemma, and through the extracellular matrix to the tendon. Here we examine the data that support this model and the sarcolemmal properties and structures, termed "costameres," that are consistent with it. PMID:12715970

Bloch, Robert J; Gonzalez-Serratos, Hugo

2003-04-01

480

Evaluation of a positioning method for equine lateral stifle scintigrams  

PubMed Central

Background The current lack of a standardized protocol for positioning of the gamma camera relative to the horse limb in a lateral stifle scintigram, and thus the reliance on subjective positioning, may be a cause of diagnostic error and inter-operator variability due to variations of the view angle. The aims of this study were to develop a reliable method to obtain a lateral scintigram of the equine stifle based on fixed anatomical landmarks and measure the resulting foot to gamma camera angle on sequential measurements of the same horse and of different horses Methods Technetium filled capsules were glued on the skin on sites adjacent to the origin of the medial and lateral femorotibial collateral ligaments in 22 horses using ultrasound guidance. A lateral view of the stifle was defined as the image where the two radioactive point sources were aligned vertically (point sources guided method). Five sequential lateral acquisitions (one to five) of the stifle with the point sources vertically aligned were acquired in each horse, and the angle between the mid-sagittal foot-axis and the vertical axis of the gamma camera (FC angle) was measured for each of these acquisitions Results For acquisition group one to five, the mean of the means FC angle was 91.6?±?2° (2SD) and the coefficient of variation (COV) was 1.1%. In the 22 horses the 95% CI for the mean FC angles was 91.6°?±?12.1° (2SD) and the COV was 6.6%. Conclusions The use of point sources to guide gamma camera position results in less variation in the lateral scintigram than if the distal limb is used as guidance due to a difference in FC angle between horses. The point source guided positioning method is considered suitable as a reference standard method to obtain lateral scintigrams of the equine stifle, and it will be of value in clinical scintigraphy and research. The use of alignment of specifically located point sources may also be applied in other regions to standardize scintigraphic views.

2012-01-01

481

VEP indices of cortical lateral interactions in epilepsy treatment.  

PubMed

We extend Spekreijse's strategy for analyzing lateral interactions in visual evoked potentials (VEPs) to clinical neurophysiologic testing of patients with epilepsy. Stimuli consisted of the radial windmill/dartboard pattern [Ratliff, F., & Zemon, V. (1982). Some new methods for the analysis of lateral interactions that influence the visual evoked potential. In: Bodis-Wollner (Ed.), Evoked potentials, Vol. 388. (pp. 113-124). New York: Annals of the New York Academy of Sciences.] and conventional checkerboards. The fundamental and 2nd-harmonic components of the steady-state responses were used to calculate indices reflecting facilitatory (FI) and suppressive (SI) cortical interactions. We carried out two studies. In the first, VEPs in 38 patients receiving antiepileptic drug (AED) therapy were compared to those of age-matched controls. For three AEDs (tiagabine, topiramate, and felbamate), addition of the drug did not change the FI and SI compared to baseline values or those of normal controls. However, the addition of gabapentin was associated with an increase of the FI, and this change was reversed when the medication was withdrawn. This suggested a medication-specific change in cortical lateral interactions. The second study focused on the effects of neurostimulation therapy. Eleven epilepsy patients receiving chronic vagus nerve stimulation (VNS) treatment were tested. By comparing VEPs recorded with the stimulator on (Stim-ON) and turned off (Stim-OFF) in the same session, we determined that VNS did not have a short-acting effect on lateral interactions. However, when compared with normal controls, the VNS patients had a significantly smaller SI (p<.05), but no difference in the FI, demonstrating the presence of a chronic effect. We conclude that with the appropriate stimuli, VEPs can be used as a measure of cortical lateral interactions in normals and epileptic patients, and demonstrate specific changes in these interactions associated with certain treatment modalities. PMID:18572221

Conte, Mary M; Victor, Jonathan D

2009-05-01

482