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1

Lateral epicondylitis  

Microsoft Academic Search

Summary 139 limbs from embalmed specimens were dissected to reveal the attachments of extensor muscles in the vicinity of the lateral epicondyle. M. extensor carpi radialis brevis was found to consist of a keelshaped tendon with attachments to m. extensor carpi radialis longus, m. extensor digitorum communis, m. supinator; and to the radial collateral ligament, the orbicular ligament, the capsule

C. A. Briggs; B. G. Elliott

1985-01-01

2

ATIVIDADE ANTIMICROBIANA DE Jacaranda mimosaefolia D. DON  

Microsoft Academic Search

RESUMO: Foram realizados ensaios microbiológicos para avaliar a atividade antibacteriana e antifúngica do extrato aquoso de folhas de Jacaranda mimosaefolia D. Don, contra quatro diferentes microrganismos. O extrato aquoso apresentou resultados significativos frente a Staphylococcus aureus ATCC 6538P, Staphylococcus epidermidis ATCC 12128, Escherichia coli ATCC 10536 e contra Saccharomyces cerevisiae ATCC 2601. Verificou-se, porém, diâmetros maiores nas zonas de inibição

3

Function Lateralization via Measuring Coherence Laterality  

PubMed Central

A data-driven approach for lateralization of brain function based on the spatial coherence difference of functional MRI (fMRI) data in homologous regions-of-interest (ROI) in each hemisphere is proposed. The utility of using coherence laterality (CL) to determine function laterality was assessed first by examining motor laterality using normal subjects’ data acquired both at rest and with a simple unilateral motor task and subsequently by examining mesial temporal lobe memory laterality in normal subjects and patients with temporal lobe epilepsy. The motor task was used to demonstrate that CL within motor ROI correctly lateralized functional stimulation. In patients with unilateral epilepsy studied during a scene-encoding task, CL in a hippocampus-parahippocampus-fusiform (HPF) ROI was concordant with lateralization based on task activation, and the CL index (CLI) significantly differentiated the right side group to the left side group. By contrast, normal controls showed a symmetric HPF CLI distribution. Additionally, similar memory laterality prediction results were still observed using CL in epilepsy patients with unilateral seizures after the memory encoding effect was removed from the data, suggesting the potential for lateralization of pathological brain function based on resting fMRI data. A better lateralization was further achieved via a combination of the proposed approach and the standard activation based approach, demonstrating that assessment of spatial coherence changes provides a complementary approach to quantifying task-correlated activity for lateralizing brain function.

Wang, Ze; Mechanic-Hamilton, Dawn; Pluta, John; Glynn, Simon; Detre, John A.

2009-01-01

4

OS EFEITOS DA APRENDIZAGEM PSICOMOTORA NO CONTROLE DAS ATIVIDADES DE LOCOMOÇÃO SOBRE OBSTÁCULOS EM CRIANÇAS COM DEFICIÊNCIA DA VISÃO THE EFFECTS OF PSYCHOMOTOR LEARNING ON THE CONTROL OF LOCOMOTION  

Microsoft Academic Search

RESUMO: considerando que a visão é um dos sistemas sensoriais mais importantes na locomoção pois fornece informação tanto do ambiente quanto da postura e dos movimentos corporais, este estudo analisou os efeitos de um programa de treinamento perceptivo-motor no controle das atividades de locomoção em seis crianças com deficiências da visão. Para tanto, realizou-se a avaliação da locomoção durante a

Luiz Cezar; Janine Eliza de Oliveira; Silva PASSOS; Luiz Gonçalves

5

Lateral collateral ligament (image)  

MedlinePLUS

The lateral collateral ligament connects the end of the femur (thigh) to the top of the fibula (the thin bone that runs next to the shin bone). The lateral collateral ligament provides stability against varus stress. Varus stress ...

6

Lateral canthal surgery.  

PubMed

The lateral canthus is a delicate and complicated three-dimensional structure with function relevant to the health of the ocular surface. Dysfunction of the lateral canthus, due to aging changes or iatrogenic trauma, results in ocular morbidity ranging from chronic irritation to tearing to recalcitrant keratopathy. From an aesthetic standpoint, symmetric, normally positioned lateral canthi are cornerstones of youthful periorbital appearance, disruption of which leads to cosmetically significant deformity or asymmetry. Reconstruction of the lateral canthus is important in the rehabilitation of the aging eyelid and an unfortunate necessity after failed lateral canthal surgery. The common methods for improving or maintaining position, tone, and shape of the lower eyelid and lateral canthus use tightening or shortening the lower eyelid horizontally, keeping the canthal angle in an appropriate vertical level, and hugging the ocular surface. Many techniques have been described for the reconstruction of the lateral canthus in functional conditions or for aesthetic purposes. These methods have met with varying success. In this article, we begin with a discussion of the anatomy and physiology of the lateral canthus, followed by clinical examples of lateral canthal abnormalities and underlying pathophysiologies. A review of surgical options for the lateral canthus is presented with concluding remarks on postoperative complications. PMID:20524167

Chong, Kelvin Kam-Lung; Goldberg, Robert A

2010-06-03

7

Lateralization of Huggins pitch.  

PubMed

The Huggins pitch is a sensation of pitch generated from a broadband noise having a narrowband boundary region where the interaural phase difference varies rapidly as a function of frequency. Models of binaural hearing predict that the pitch image should be well lateralized. A direct psychophysical experimental method was used to estimate the lateral positions of Huggins pitch images with two different forms of phase boundaries, linear phase and stepped phase. A third experiment measured the lateral positions of sine tones with controlled interaural phase differences. The results showed that the lateralization of Huggins pitch stimuli was similar to that of the corresponding sine tones and that the lateralizations of the two forms of Huggins pitch phase boundaries were even more similar to one another. Both Huggins pitches and sine tones revealed strong laterality compression (exponent approximately 0.5). Ambiguous stimuli, with an interaural phase difference of 180 degrees , were consistently lateralized on one side or the other according to individual asymmetries-an effect called "earedness." An appendix to this article develops a new first-order lateralization model, the salient phase density model, which combines attributes of previous models of dichotic pitch lateralization. PMID:19206813

Zhang, Peter Xinya; Hartmann, William M

2008-12-01

8

Cerebral Lateralization and Aggression.  

ERIC Educational Resources Information Center

|A resurgence of interest in the relationship between cerebral lateralization (the functional asymmetry of the cerebral cortex) and aggression has occurred. Most recent studies have found that individuals with abnormal patterns of lateralization are overrepresented among violent individuals. Intervening variables (such as drug and alcohol abuse)…

Hillbrand, Marc; And Others

1994-01-01

9

Treatment of Lateral Epicondylitis  

Microsoft Academic Search

Lateral epicondylitis is a common overuse syndrome of the extensor tendons of the forearm. It is sometimes called tennis elbow, although it can occur with many activities. The condition affects men and women equally and is more common in persons 40 years or older. Despite the prevalence of lateral epicondylitis and the numerous treatment strategies available, relatively few high-quality clinical

GREG W. JOHNSON; KARA CADWALLADER; SCOT B. SCHEFFEL

2007-01-01

10

Reading Disability and Laterality.  

ERIC Educational Resources Information Center

|The purpose of this study was to determine how retarded readers differed from normal readers in the various ways laterality is manifested. An additional purpose was to investigate the development of laterality as seen across several age levels. Subjects were 80 white male 9-, 10-, 11-, and 12-year-olds from regular classrooms in suburban…

Sparrow, Sara S.

11

Lateralization of Huggins pitch  

Microsoft Academic Search

The Huggins pitch is a sensation of pitch generated from a broadband noise having a narrowband boundary region where the interaural phase difference varies rapidly as a function of frequency. Models of binaural hearing predict that the pitch image should be well lateralized. A direct psychophysical experimental method was used to estimate the lateral positions of Huggins pitch images with

Peter Xinya Zhang; William M. Hartmann

2008-01-01

12

Lateral patellofemoral ligament reconstruction.  

PubMed

Abstract Medial dislocation of the patella is a disabling condition; there are several reports in the literature describing this condition and its association with failed lateral retinacular release. The diagnosis and treatment of medial subluxation of the patella may be difficult. Direct repair or imbrication of the lateral retinaculum provides initial stability but a noticeable increase in medial excursion usually reappears. In this article, we describe a simple and reproducible technique to reconstruct the lateral patellofemoral ligament with autogenous tissue that is based on the basic principles of all ligament reconstruction. Reconstruction of the lateral patellofemoral ligament is useful in eliminating the symptoms related to medial instability of the patella after failed lateral retinacular release; however, it must be considered a salvage procedure because it does not address the pathomechanics that led to the initial patellofemoral symptoms. PMID:15525935

Teitge, Robert A; Torga Spak, Roger

2004-11-01

13

Laparoscopic lateral pancreaticojejunostomy  

Microsoft Academic Search

Background  Lateral pancreaticojejunostomy is considered as the standard surgery for chronic pancreatitis. Yet there are very few reports\\u000a of this procedure being done laparoscopically. We present our experience with laparoscopic lateral pancreaticojejunostomy\\u000a till date and describe our technique.\\u000a \\u000a \\u000a \\u000a Material and method  Since 1997, we have done 12 laparoscopic lateral pancreatojejunostomies. There were 9 females and 3 males and the average\\u000a age was

C. Palanivelu; R. Shetty; K. Jani; P. S. Rajan; K. Sendhilkumar; R. Parthasarthi; V. Malladi

2006-01-01

14

Sexuality in Later Life  

MedlinePLUS

... normal operations can be found at USA.gov . Sexuality in Later Life Many people want and need ... Depression can be treated. What Else May Cause Sexuality Problems? Surgery. Many of us worry about having ...

15

Laterally bendable belt conveyor  

DOEpatents

An endless, laterally flexible and bendable belt conveyor particularly adapted for coal mining applications in facilitating the transport of the extracted coal up- or downslope and around corners in a continuous manner is disclosed. The conveying means includes a flat rubber belt reinforced along the middle portion thereof along which the major portion of the belt tension is directed so as to cause rotation of the tubular shaped belt when trammed around lateral turns thus preventing excessive belt bulging distortion between adjacent belt supports which would inhibit belt transport. Pretension induced into the fabric reinforced flat rubber belt by conventional belt take-up means supports the load conveyed when the belt conveyor is making lateral turns. The carrying and return portions of the belt are supported and formed into a tubular shape by a plurality of shapers positioned along its length. Each shaper is supported from above by a monorail and includes clusters of idler rollers which support the belt. Additional cluster rollers in each shaper permit the belt supporting roller clusters to rotate in response to the belt's operating tension imposed upon the cluster rollers by induced lateral belt friction forces. The freely rotating roller clusters thus permit the belt to twist on lateral curves without damage to itself while precluding escape of the conveyed material by effectively enclosing it in the tube-shaped, inner belt transport length.

Peterson, William J. (Coraopolis, PA)

1985-01-01

16

Components in Hemispheric Lateralization.  

ERIC Educational Resources Information Center

The fact that there is an imperfect correlation between the asymmetrical function of the two halves of the brain and handedness has been a source of puzzlement for many investigators. Many theories have been proposed to explain handedness and why handedness does not correlate perfectly with other measures of lateralization. To assess the…

Lynes, Sharon C. S. L.; And Others

17

Components in Hemispheric Lateralization.  

ERIC Educational Resources Information Center

|The fact that there is an imperfect correlation between the asymmetrical function of the two halves of the brain and handedness has been a source of puzzlement for many investigators. Many theories have been proposed to explain handedness and why handedness does not correlate perfectly with other measures of lateralization. To assess the…

Lynes, Sharon C. S. L.; And Others

18

Suboccipital Lateral Approaches (Retrosigmoid)  

Microsoft Academic Search

\\u000a The lateral suboccipital or the retrosigmoid approach (RSA) was developed by Fedor Krause and utilized for the first time\\u000a by him in 1898. During the following decades it was developed and became one of the main and most frequently applied operative\\u000a approaches in neurosurgery [1–5]. Various pathological entities located in the cerebellopontine angle (CPA), the internal auditory canal (IAC), the

Madjid Samii; Venelin M. Gerganov

19

Juvenile amyotrophic lateral sclerosis  

Microsoft Academic Search

Juvenile amytrophic lateral sclerosis (JALS) is a type of motor neuron disease presenting before 25 years of age. It is characterized\\u000a by a combination of upper and lower motor signs. It may be familial or sporadic. We are reporting a sporadic case of JALS\\u000a with onset of symptoms at 4 years of age. Diagnostic criteria and a brief review of

Anju Aggarwal; Shashiraj

2006-01-01

20

Juvenile amyotrophic lateral sclerosis.  

PubMed

Juvenile amytrophic lateral sclerosis (JALS) is a type of motor neuron disease presenting before 25 years of age. It is characterized by a combination of upper and lower motor signs. It may be familial or sporadic. We are reporting a sporadic case of JALS with onset of symptoms at 4 years of age. Diagnostic criteria and a brief review of literature are presented. PMID:16567917

Aggarwal, Anju; Shashiraj

2006-03-01

21

Five Years Later  

Microsoft Academic Search

In 2000, three groups of health sciences librarians—new library school graduates, those currently working at a medical library, and medical library directors—were interviewed about the status and future of medical reference librarianship. Five years later this follow-up article summarizes the responses from many of the same librarians about the biggest changes, newest trends, evolving roles, challenges, and hopes for the

Nancy W. Clemmons; Susan L. Clemmons

2005-01-01

22

Lateral lumbar interbody fusion.  

PubMed

Since its inception in the year 2001 the minimally invasive trans-psoas Lateral Lumbar Interbody Fusion (LLIF) approach has gained significant favor among spine surgeons. It is now routinely utilized to treat an array of spinal pathologies including degenerative disc disease, low grade spondylolisthesis, and adult spinal deformity. The intent of this video is to provide a step by step account of the basic procedural details when performing the LLIF procedure for a single level broad based degenerated lumbar disc with herniation. The video can be found here: http://youtu.be/dZFMqmCz6Q8. PMID:23829851

Kanter, Adam S; Gandhoke, Gurpreet S

2013-07-01

23

Lateral Abdominal Wall Reconstruction  

PubMed Central

Lateral abdominal wall (LAW) defects can manifest as a flank hernias, myofascial laxity/bulges, or full-thickness defects. These defects are quite different from those in the anterior abdominal wall defects and the complexity and limited surgical options make repairing the LAW a challenge for the reconstructive surgeon. LAW reconstruction requires an understanding of the anatomy, physiologic forces, and the impact of deinnervation injury to design and perform successful reconstructions of hernia, bulge, and full-thickness defects. Reconstructive strategies must be tailored to address the inguinal ligament, retroperitoneum, chest wall, and diaphragm. Operative technique must focus on stabilization of the LAW to nonyielding points of fixation at the anatomic borders of the LAW far beyond the musculofascial borders of the defect itself. Thus, hernias, bulges, and full-thickness defects are approached in a similar fashion. Mesh reinforcement is uniformly required in lateral abdominal wall reconstruction. Inlay mesh placement with overlying myofascial coverage is preferred as a first-line option as is the case in anterior abdominal wall reconstruction. However, interposition bridging repairs are often performed as the surrounding myofascial tissue precludes a dual layered closure. The decision to place bioprosthetic or prosthetic mesh depends on surgeon preference, patient comorbidities, and clinical factors of the repair. Regardless of mesh type, the overlying soft tissue must provide stable cutaneous coverage and obliteration of dead space. In cases where the fasciocutaneous flaps surrounding the defect are inadequate for closure, regional pedicled flaps or free flaps are recruited to achieve stable soft tissue coverage.

Baumann, Donald P.; Butler, Charles E.

2012-01-01

24

Lateral conduction infrared photodetector  

SciTech Connect

A photodetector for detecting infrared light in a wavelength range of 3-25 .mu.m is disclosed. The photodetector has a mesa structure formed from semiconductor layers which include a type-II superlattice formed of alternating layers of InAs and In.sub.xGa.sub.1-xSb with 0.ltoreq.x.ltoreq.0.5. Impurity doped regions are formed on sidewalls of the mesa structure to provide for a lateral conduction of photo-generated carriers which can provide an increased carrier mobility and a reduced surface recombination. An optional bias electrode can be used in the photodetector to control and vary a cut-off wavelength or a depletion width therein. The photodetector can be formed as a single-color or multi-color device, and can also be used to form a focal plane array which is compatible with conventional read-out integrated circuits.

Kim, Jin K. (Albuquerque, NM); Carroll, Malcolm S. (Albuquerque, NM)

2011-09-20

25

Sensorimotor and cognitive laterality profiles  

Microsoft Academic Search

Different types of functional asymmetries, which form individual laterality profiles, were compared with the use of a battery of sensorimotor and cognitive laterality tests (TOPOS), the Benziger thinking style assessment (BTSA) test, the Cattell 17PF test, and psychosemantic multidimensional scaling. The proportion of men was shown to be higher among individuals with the left-side, symmetrical, and intersecting motor laterality profiles.

T. V. Chernigovskaya; T. A. Gavrilova; A. V. Voinov; K. N. Strel’nikov

2005-01-01

26

Laterally oscillating nitinol engine  

SciTech Connect

This patent describes a laterally oscillating nitinol engine comprising: a first L-shaped drive member journalled for pivoting horizontal oscillation about the juncture of the legs of the L-shaped member, a second drive member journalled for pivoting about a point proximate the outboard end of the shorter leg of the L-shaped member at a distance from the pivot journal of the L-shaped member, a bearing block secured to the end of longer leg of the L-shaped and having a guide hole. The second member extending through the guide hole and arranged to reciprocate therein, a shape memory alloy power element disposed in flexure secured at its ends to the bearing block and to the second member intermediate the sliding connection with the bearing block and the pivotal connection of the second member, means for disposing different temperature baths below the element whereby as the drive members oscillate about their journals the element alternately dips into one bath and then the other, and means for absorbing a portion of the energy developed by the engine and moving the power element from the cold bath to the hot bath.

Banks, R.

1987-09-08

27

Amyotrophic lateral sclerosis  

PubMed Central

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterised by progressive muscular paralysis reflecting degeneration of motor neurones in the primary motor cortex, corticospinal tracts, brainstem and spinal cord. Incidence (average 1.89 per 100,000/year) and prevalence (average 5.2 per100,000) are relatively uniform in Western countries, although foci of higher frequency occur in the Western Pacific. The mean age of onset for sporadic ALS is about 60 years. Overall, there is a slight male prevalence (M:F ratio~1.5:1). Approximately two thirds of patients with typical ALS have a spinal form of the disease (limb onset) and present with symptoms related to focal muscle weakness and wasting, where the symptoms may start either distally or proximally in the upper and lower limbs. Gradually, spasticity may develop in the weakened atrophic limbs, affecting manual dexterity and gait. Patients with bulbar onset ALS usually present with dysarthria and dysphagia for solid or liquids, and limbs symptoms can develop almost simultaneously with bulbar symptoms, and in the vast majority of cases will occur within 1–2 years. Paralysis is progressive and leads to death due to respiratory failure within 2–3 years for bulbar onset cases and 3–5 years for limb onset ALS cases. Most ALS cases are sporadic but 5–10% of cases are familial, and of these 20% have a mutation of the SOD1 gene and about 2–5% have mutations of the TARDBP (TDP-43) gene. Two percent of apparently sporadic patients have SOD1 mutations, and TARDBP mutations also occur in sporadic cases. The diagnosis is based on clinical history, examination, electromyography, and exclusion of 'ALS-mimics' (e.g. cervical spondylotic myelopathies, multifocal motor neuropathy, Kennedy's disease) by appropriate investigations. The pathological hallmarks comprise loss of motor neurones with intraneuronal ubiquitin-immunoreactive inclusions in upper motor neurones and TDP-43 immunoreactive inclusions in degenerating lower motor neurones. Signs of upper motor neurone and lower motor neurone damage not explained by any other disease process are suggestive of ALS. The management of ALS is supportive, palliative, and multidisciplinary. Non-invasive ventilation prolongs survival and improves quality of life. Riluzole is the only drug that has been shown to extend survival.

Wijesekera, Lokesh C; Leigh, P Nigel

2009-01-01

28

CT navigated lateral interbody fusion.  

PubMed

Lateral interbody fusion techniques are heavily reliant on fluoroscopy for retractor docking and graft placement, which expose both the patient and surgeon to high doses of radiation. Use of image-guided technologies with CT-based images, however, can eliminate this radiation exposure for the surgeon. We describe the surgical technique of performing lateral lumbar interbody fusion using CT navigation. PMID:23931938

Drazin, Doniel; Liu, John C; Acosta, Frank L

2013-08-06

29

Lateral motion tracking of automobiles  

Microsoft Academic Search

Radar sensors, though successful in range parameters tracking, fall short in lateral characteristics tracking. On the other hand, vision systems carry out perfect estimation for lateral motion, but range parameters estimation does not surpass the performance of radar. The exact estimation of vehicle's motion characteristics appears to be a crucial issue in modern automobile collision avoidance systems. Thus, a fusion

Angelos Amditis; Nikolaos Floudas; Aris Polychronopoulos

30

VOLCANO INSTABILITY AND LATERAL COLLAPSE  

Microsoft Academic Search

Active volcanoes are dynamically evolving structures, the life-cycles of which are punctuated by episodes of flank instability and lateral failure. Such behaviour is now recognised as ubiquitous and lateral collapses are estimated to have occurred at least four times a century over the past 500 years. In the Andes, three quarters of the large volcanic edifices have experienced collapse, while

W. J. McGuire

2003-01-01

31

Lateral Thinking and Technology Education  

Microsoft Academic Search

The emergence of lateral thinking in recent years is a natural reaction to the enormous increase of information a human being is “bombarded” with, in the post industrial revolution era. Vertical thinking, with its sequential and fixed-order rules, which has been the foundation of traditional education, is increasingly being complemented by lateral thinking which aims at freeing the mind from

Shlomo Waks

1997-01-01

32

Riluzole for amyotrophic lateral sclerosis.  

PubMed

Around one in 20,000 adults in the UK will develop amyotrophic lateral sclerosis, the commonest variant of motor neurone disease. Riluzole (Rilutek-Rhône-Poulenc Rorer) was launched in the UK in August 1996 as "the first anti-excitotoxic agent proven to extend life in amyotrophic lateral sclerosis". We review the clinical data on the effectiveness of riluzole and assess its place in the management of amyotrophic lateral sclerosis, a condition that is invariably fatal and has a median survival time from symptom onset of about 2.5 years. PMID:9282413

1997-02-01

33

Lateral collateral ligament (LCL) injury  

MedlinePLUS

LCL injury; Knee injury - lateral collateral ligament (LCL) ... ligament helps keep the outer side of the knee joint stable. ... by pressure or an injury that pushes the knee joint from the inside, which results in stress ...

34

Lateral Dominance and Reading Disability.  

ERIC Educational Resources Information Center

|Theory and research on the relation of lateral dominance to the causation of reading disability are reviewed. Both direct and indirect measures of cerebral hemisphere functioning are considered. (SBH)|

Harris, Albert J.

1979-01-01

35

Lateral Dampers for Thrust Bearings.  

National Technical Information Service (NTIS)

The development of lateral damping schemes for thrust bearings was examined, ranking their applicability to various engine classes, selecting the best concept for each engine class and performing an in-depth evaluation. Five major engine classes were cons...

D. H. Hibner D. R. Szafir

1985-01-01

36

"Secondary signs of lateralization" in apogeotropic lateral canalolithiasis  

PubMed Central

Summary The diagnosis of lateral canalolithiasis is based on the typical finding of the horizontal paroxysmal positional nystagmus induced by the Pagnini-Mc Clure manoeuvre. This technique usually identifies also the affected side, namely, the side where the paroxysmal nystagmus is more intense in geotropic forms and the side where the paroxysmal nystagmus is less intense in apogeotropic forms. However, this method is not always applicable since, especially in apogeotropic forms, the intensity of the nystagmus is not so distinctly different between the two sides. Further useful signs to identify the affected side have been described in the Literature: Pseudo-spontaneous nystagmus in the sitting position; Leaning and Bowing nystagmus; Null-point in the vertical plane; Sitting to supine positioning nystagmus; Null-point in the horizontal plane. They are fully explained at pathophysiological level by the mechanism of canalolithiasis, as they are caused by otoliths moving in the ampullopetal direction in the non-ampullary segment (geotropic canalolithiasis) of the lateral canal or in ampullofugal direction in the ampullary segment (apogeotropic canalolithiasis) of the lateral canal. In other words, the movement of otoliths determines excitatory or inhibitory endolymphatic flow that generates specific nystagmic eye-movements. Authors analyse the characteristics of these signs, that they define as “Secondary signs of lateralization”, in 64 cases of apogeotropic lateral canalolithiasis. A decisive contribution of the “Secondary signs of lateralization” to diagnose the pathological side has been verified in 13 out of 64 cases, whereas, in all other cases, Pagnini-Mc Clure diagnostic manoeuvre proved successful in correctly identifying the affected side by itself. Among the “Secondary signs of lateralization”, the Pseudo-spontaneous nystagmus in the sitting position and the Sitting to the supine positioning nystagmus were particularly useful, due to both their frequency and their easy detection, as they do not require additional manoeuvres besides those usually performed during health examination of a patient affected by lateral canalolithiasis. In conclusion, the Authors propose a decision-making algorithm to diagnose and treat lateral canalolithiasis based on the attempt to obtain as much information as possible for a correct diagnosis, with the least trouble and inconvenience for patients.

Califano, L; Melillo, MG; Mazzone, S; Vassallo, A

2010-01-01

37

Borehole optical lateral displacement sensor  

DOEpatents

There is provided by this invention an optical displacement sensor that utilizes a reflective target connected to a surface to be monitored to reflect light from a light source such that the reflected light is received by a photoelectric transducer. The electric signal from the photoelectric transducer is then imputed into electronic circuitry to generate an electronic image of the target. The target`s image is monitored to determine the quantity and direction of any lateral displacement in the target`s image which represents lateral displacement in the surface being monitored. 4 figs.

Lewis, R.E.

1998-10-20

38

VIEW OF PIEDMONT AVENUE AT INTERSECTION OF DURANT AVENUE WITH ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

VIEW OF PIEDMONT AVENUE AT INTERSECTION OF DURANT AVENUE WITH DOME OF THE INTERNATIONAL HOUSE AT 2299 PIEDMONT AVENUE. BY GEORGE W. KELHAM, 1929, SEEN FROM SW CORNER LOOKING NORTH. Photograph by Fredrica Drotos and Michael Kelly, July 9, 2006 - Piedmont Way & the Berkeley Property Tract, East of College Avenue between Dwight Way & U.C. Memorial Stadium, Berkeley, Alameda County, CA

39

VIEW OF PIEDMONT AVENUE BETWEEN CHANNING WAY AND DURANT AVENUE. ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

VIEW OF PIEDMONT AVENUE BETWEEN CHANNING WAY AND DURANT AVENUE. 2325 PIEDMONT (MRS. F.W. FISH HOUSE DESIGNED BY CHARLES S. KAISER, 1910. SEEN FROM WEST SIDE OF PIEDMONT LOOKING NORTH. Photograph by Fredrica Drotos and Michael Kelly, July 9, 2006 - Piedmont Way & the Berkeley Property Tract, East of College Avenue between Dwight Way & U.C. Memorial Stadium, Berkeley, Alameda County, CA

40

Future Research Directions in Laterality  

Microsoft Academic Search

This paper considers the current conceptual state of research into neuropsychological laterality and considers some issues which might appropriately be considered for the forward development of the field. It considers the biological context which has been adopted for these studies and the psychological significance of performance asymmetries. A principal emphasis of the paper is the degree to which inferences, rather

J. Graham Beaumont

1997-01-01

41

Multiple Resources and Brain Laterality.  

National Technical Information Service (NTIS)

Two studies were completed to test the multiple resources model of information processing using tachistoscopic lateralized-input techniques. In Exp. 1 37 normal, dextral subjects, 18 men aged 18-21yr. and 19 women 18-21yr. responded manually to a visuo-sp...

E. H. Galluscio

1984-01-01

42

Enhancing Satisfaction in Later Life  

Microsoft Academic Search

Enhancement of later life satisfaction of long-term care residents is the purpose of this study. Seventy-eight men, residents of two Veterans Affairs nursing home units, completed a survey measuring personal characteristics, relationships with family and friends, and levels of life satisfaction. Findings show that the \\

Husam F. Ghusn; David Hyde; Ellen S. Stevens; Mary Hyde; Thomas A. Teasdale

1996-01-01

43

Color Realism and Hemispheric Laterality.  

ERIC Educational Resources Information Center

|This study investigated the interaction between cognitive lateral functions and pictorial recognition memory for pictures presented in three different color modes. The stimulus materials used were slides selected from a pool of travel and general geographic scenery slides taken in various parts of North America. One third of the slides were…

Waltz, Esther; Berry, Louis H.

44

Excitotoxicity and Amyotrophic Lateral Sclerosis  

Microsoft Academic Search

Since its description by Charcot more than 130 years ago, the pathogenesis of selective motor neuron degeneration in amyotrophic lateral sclerosis (ALS) remains unsolved. Over the years, many pathogenic mechanisms have been proposed. Amongst others these include: oxidative stress, excitotoxicity, aggregate formation, inflammation, growth factor deficiency and neurofilament disorganization. This multitude of contributing factors indicates that ALS is a complex

P. Van Damme; M. Dewil; W. Robberecht; L. Van Den Bosch

2005-01-01

45

Color Realism and Hemispheric Laterality.  

ERIC Educational Resources Information Center

This study investigated the interaction between cognitive lateral functions and pictorial recognition memory for pictures presented in three different color modes. The stimulus materials used were slides selected from a pool of travel and general geographic scenery slides taken in various parts of North America. One third of the slides were…

Waltz, Esther; Berry, Louis H.

46

Sleep Strategies Later in Life  

MedlinePLUS Videos and Cool Tools

Sleep Strategies Later in Life (4:22) Sleep problems are not inevitable as we age, though individuals need to pay attention to healthy sleep habits. choose settings to watch video: Windows Media Player - high | low QuickTime - high | low

47

Anxiety and Lateral Cerebral Function  

ERIC Educational Resources Information Center

|Examines the effect of stressful and nonstressful experimental situations upon the processing capacity of each cerebral hemisphere, through observing the differential performance tasks presented to right and left visual half-fields (VHFs). Also examines attentional bias and lateral eye movements. (Author/RK)|

Tucker, Don M.; And Others

1978-01-01

48

Biomarkers for Amyotrophic Lateral Sclerosis.  

National Technical Information Service (NTIS)

The invention provides a method for diagnosing amyotrophic lateral sclerosis (ALS) in a subject, a method for assessing the effectiveness of a drug in treating ALS, and a method for determining the site of onset of ALS in a subject. Each method comprises ...

R. P. Bowser S. Ranganathan

2004-01-01

49

Observation of lateral vehicle dynamics  

Microsoft Academic Search

By observation of lateral vehicle dynamics the detection of critical driving situations is made possible, as well as the estimation of adhesion characteristics during cornering. This paper presents a comparison of a linear and a nonlinear observer for the vehicle and tyre side-slip angles. The modelling, especially the model reduction and simplification, is shown.

U. Kiencke; A. Daiß

1997-01-01

50

Lateral diffusion in sphingomyelin bilayers.  

PubMed

Sphingomyelin (SM) is an important lipid of eukaryotic cellular membranes and neuronal tissues. We studied lateral diffusion in macroscopically oriented bilayers of synthetic palmitoylsphingomyelin (PSM) and natural sphingomyelins of egg yolk (eSM), bovine brain (bSM) and bovine milk (mSM) by pulsed field gradient NMR (PFG NMR) in the temperature range 45-60 °C. We found that the mean values of lateral diffusion coefficients (LDCs) of SMs are 1.9-fold lower compared with those of dipalmitoylphosphatidylcholine (DPPC), which is similar in molecular structure. This discrepancy could be explained by the characteristics of intermolecular SM interactions. The LDCs of different SMs differ: egg SM is most similar to PSM; both of them have a 10% higher LDC value compared with the other two natural SMs. Besides, all natural SMs show a complicated form of the spin-echo diffusion decay (DD), which is an indicator of a distribution of LDC values in bilayers. This peculiarity is explained by the broad distributions of hydrocarbon chain lengths of the natural SMs studied here, especially mSM and bSM. We confirmed the relationship between chain length and LDC in the bilayers by computer analysis of a set of (1)H NMR spectra obtained by scanning the value of the pulsed field gradient. There is a correlation between lower LDC values and SM molecules with longer acyl chains. The most probable mechanisms by which long-chain SM molecules decrease their lateral diffusion relative to the average value are protrusion into the other side of the bilayer or lateral separation into areas that diverge with their LDCs. PMID:21031608

Filippov, A V; Rudakova, M A; Munavirov, B V

2010-12-01

51

Subcortical Laterality of Speech Encoding  

PubMed Central

It is well established that in the majority of the population language processing is lateralized to the left hemisphere. Evidence suggests that lateralization is also present in the brainstem. In the current study, the syllable /da/ was presented monaurally to the right and left ears and electrophysiological responses from the brainstem were recorded in adults with symmetrical interaural click-evoked responses. Responses to the right-ear presentation occurred earlier than those to left-ear presentation in two peaks of the frequency following response (FFR) and approached significance for the third peak of the FFR and the offset peak. Interestingly, there were no differences in interpeak latencies indicating the response to right-ear presentation simply occurred earlier over this region. Analyses also showed more robust frequency encoding when stimuli were presented to the right ear than the left ear. The effect was found for the harmonics of the fundamental that correspond to the first formant of the stimulus, but was not seen in the fundamental frequency range. The results suggest that left lateralization of processing acoustic elements important for discriminating speech extends to the auditory brainstem and that these effects are speech specific.

Hornickel, Jane; Skoe, Erika; Kraus, Nina

2009-01-01

52

Clinical neurogenetics: amyotrophic lateral sclerosis.  

PubMed

Our understanding of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease, is expanding rapidly as its genetic causes are uncovered. The pace of new gene discovery over the last 5 years has accelerated, providing new insights into the pathogenesis of disease and highlighting biological pathways as targets for therapeutic development. This article reviews our current understanding of the heritability of ALS and provides an overview of each of the major ALS genes, highlighting their phenotypic characteristics and frequencies as a guide for clinicians evaluating patients with ALS. PMID:24176417

Harms, Matthew B; Baloh, Robert H

2013-11-01

53

Early growth and later atherosclerosis.  

PubMed

The concept that early growth has long-term biological effects is based on extensive studies in animals dating from the 1930s. More recently, compelling evidence for a long-term influence of early growth on later health has also emerged in humans. Substantial data now support the hypothesis that 'accelerated', or too fast infant growth, increases the propensity to obesity, glucose intolerance, raised blood pressure, dyslipidaemia and endothelial dysfunction, the clustering of risk factors which predispose to the development of atherosclerotic cardiovascular disease (CVD). The association between infant growth and these risk factors is strong, consistent, shows a dose-response effect, and is biologically plausible. Moreover, experimental data from prospective randomized controlled trials strongly support a causal link between infant growth and later cardiovascular risk. These observations suggest, therefore, that the primary prevention of CVD should begin from as early as the first few months of life. The present review considers this evidence, the underlying mechanisms involved, and its implications for public health. PMID:23428696

Singhal, Atul

2013-02-11

54

Laterality in visual speech perception.  

PubMed

The lateralization of visual speech perception was examined in 3 experiments. Participants were presented with a realistic computer-animated face articulating 1 of 4 consonant-vowel syllables without sound. The face appeared at 1 of 5 locations in the visual field. The participants' task was to identify each test syllable. To prevent eye movement during the presentation of the face, participants had to carry out a fixation task simultaneously with the speechreading task. In one study, an eccentricity effect was found along with a small but significant difference in favor of the right visual field (left hemisphere). The same results were found with the face articulating nonlinguistic mouth movements (e.g., kiss). These results suggest that the left-hemisphere advantage is based on the processing of dynamic visual information rather than on the extraction of linguistic significance from facial movements. PMID:9706714

Smeele, P M; Massaro, D W; Cohen, M M; Sittig, A C

1998-08-01

55

49 CFR 230.105 - Lateral motion.  

Code of Federal Regulations, 2011 CFR

...2011-10-01 2011-10-01 false Lateral motion. 230.105 Section 230.105 Transportation...Tenders Running Gear § 230.105 Lateral motion. (a) Condemning limits. The total lateral motion or play between the hubs of the...

2011-10-01

56

49 CFR 230.105 - Lateral motion.  

Code of Federal Regulations, 2012 CFR

...2012-10-01 2012-10-01 false Lateral motion. 230.105 Section 230.105 Transportation...Tenders Running Gear § 230.105 Lateral motion. (a) Condemning limits. The total lateral motion or play between the hubs of the...

2012-10-01

57

Hemispheric Laterality in Music and Math  

ERIC Educational Resources Information Center

|Hemispheric laterality may be a useful concept in teaching, learning, training, and in understanding more about human development. To address this issue, a measure of hemispheric laterality was compared to musical and mathematical ability. The Human Information Processing Survey (HIPS) instrument, designed to measure hemispheric laterality, was…

Szirony, Gary Michael; Burgin, John S.; Pearson, L. Carolyn

2008-01-01

58

Later-life depression and heart failure.  

PubMed

Using a case history to illustrate key points, this article (1) highlights depression criteria, prevalence, and later-life depression presentations; (2) discusses factors contributing to later-life depression; (3) reviews the interplay between heart failure and later-life depression; and (4) suggests screening and treatment recommendations for depression in patients with heart failure. PMID:21109207

Maixner, Susan M; Struble, Laura; Blazek, Mary; Kales, Helen C

2011-01-01

59

Transcript profiling of early lateral root initiation  

Microsoft Academic Search

At the onset of lateral root initiation in Arabidopsis thaliana, the phytohormone auxin activates xylem pole pericycle cells for asymmetric cell division. However, the molecular events leading from auxin to lateral root initiation are poorly understood, in part because the few responsive cells in the process are embedded in the root and are thus difficult to access. A lateral root

Kristiina Himanen; Marnik Vuylsteke; Steffen Vanneste; Steven Vercruysse; Elodie Boucheron; Philippe Alard; Dominique Chriqui; Marc van Montagu; Dirk Inzé; Tom Beeckman

2004-01-01

60

Auxin Transport Promotes Arabidopsis Lateral Root Initiation  

Microsoft Academic Search

Lateral root development in Arabidopsis provides a model for the study of hormonal signals that regulate postembry- onic organogenesis in higher plants. Lateral roots originate from pairs of pericycle cells, in several cell files positioned opposite the xylem pole, that initiate a series of asymmetric, transverse divisions. The auxin transport inhibitor N -1-naph- thylphthalamic acid (NPA) arrests lateral root development

Ilda Casimiro; Alan Marchant; Rishikesh P. Bhalerao; Tom Beeckman; Sandra Dhooge; Ranjan Swarup; Neil Graham; Dirk Inzé; Goran Sandberg; Pedro J. Casero; Malcolm Bennett

2001-01-01

61

Exercise and amyotrophic lateral sclerosis.  

PubMed

Amyotrophic Lateral Sclerosis (ALS) is a progressive and fatal neurodegenerative disease in which much burden is geared towards end-of-life care. Particularly in the earlier stages of ALS, many people have found both physiological and psychological boosts from various types of physical exercise for disused muscles. Proper exercise is important for preventing atrophy of muscles from disuse-a key for remaining mobile for as long as possible-and as long as it is possible to exercise comfortably and safely, for preserving cardiovascular fitness. However, the typical neuromuscular patient features a great physical inactivity and disuse weakness, and for that reason many controversial authors have contested exercise in these patients during years, especially in ALS which is rapidly progressive. There is an urgent need for dissecting in detail the real risks or benefits of exercise in controlled clinical trials to demystify this ancient paradigm. Yet, recent research studies document significant benefits in terms of survival and quality of life in ALS, poor cooperation, small sample size, uncontrolled and short-duration trials, remain the main handicaps. Sedentary barriers such as early fatigue and inherent muscle misuse should be overcome, for instance with body-weight supporting systems or non-invasive ventilation, and exercise should be faced as a potential non-monotonous way for contributing to better health-related quality of life. PMID:22228269

de Almeida, J P Lopes; Silvestre, R; Pinto, A C; de Carvalho, M

2012-01-07

62

Critical band in auditory lateralization.  

PubMed

A new and powerful procedure for determining frequency analysis in the auditory system, as evidence by the critical band, is described. The onset time difference, delta T, needed to lateralize 30-msec tone bursts toward the leading ear was measured as a function of the frequency difference, delta F, between the brust in one ear and the burst in the other ear. When delta F was less than the critical band, threshold delta T was constant at 100 mu sec or less, depending on center frequency; beyond the critical band, delta T increased with delta F. These dichotically measured critical bandwidths increased from 110 Hz at a center frequency of 500 Hz to 1100 Hz at a center frequency of 6000 Hz. They were unaffected by varying signal level from 25 to 80 dB or signal duration from 10 to 300 msec. The sam e critical-band values have been measured with monaural stimuli in loudness summation, maskin, detection, phase perception, consonance, and so forth. PMID:1029081

Scharf, B; Florentine, M; Meiselman, C H

1976-12-01

63

Minimally Invasive Approaches for Lateral Epicondylitis  

Microsoft Academic Search

\\u000a Lateral epicondylitis is a painful condition that affects the lateral aspect of the elbow, usually centered around the epicondyle\\u000a of the humerus. Historically called tennis elbow, this condition occurs in both men and women, usually in the 35- to 50-year\\u000a age range, and rarely in tennis players. Patients present with laterally based elbow pain, exacerbated with repetitive stresses\\u000a to the

Bradford O. Parsons; Michael R. Hausman

64

Chondrolysis after partial lateral meniscectomy in athletes  

Microsoft Academic Search

Rapid chondrolysis after partial arthroscopic lateral meniscectomy has been seldom reported in literature. Considering the\\u000a relatively high number of partial lateral meniscectomy performed, we cannot understand why this complication is so rare. The\\u000a purpose of this paper is to report a series of athletes developing a chondrolysis associated with posterolateral corner laxity\\u000a after a partial lateral meniscectomy and attempt to

Pier Paolo Mariani; Raffaele Garofalo; Fabrizio Margheritini

2008-01-01

65

Absence of lateral palpebral raphe in Caucasians  

PubMed Central

Classical anatomical teaching reports the presence of the lateral palpebral raphe formed at the union in the preseptal and orbital parts of the orbicularis oculi muscle, or by the tendon adhering these to the underlying zygomatic bone. The lateral palpebral raphe has been shown to be absent in Asian cadavers. The current study uses both evidence from the anatomical dissection of five eyelids from three Caucasian cadavers, and histological assessment of the lateral canthus of 13 eyelids from seven Caucasian cadavers to illustrate the absence of the lateral palpebral raphe in Caucasian population.

Goold, Lucy; Kakizaki, Hirohiko; Malhotra, Raman; Selva, Dinesh

2009-01-01

66

Aeromonas hydrophila Lateral Flagellar Gene Transcriptional Hierarchy  

PubMed Central

Aeromonas hydrophila AH-3 lateral flagella are not assembled when bacteria grow in liquid media; however, lateral flagellar genes are transcribed. Our results indicate that A. hydrophila lateral flagellar genes are transcribed at three levels (class I to III genes) and share some similarities with, but have many important differences from, genes of Vibrio parahaemolyticus. A. hydrophila lateral flagellum class I gene transcription is ?70 dependent, which is consistent with the fact that lateral flagellum is constitutively transcribed, in contrast to the characteristics of V. parahaemolyticus. The fact that multiple genes are included in class I highlights that lateral flagellar genes are less hierarchically transcribed than polar flagellum genes. The A. hydrophila lafK-fliEJL gene cluster (where the subscript L distinguishes genes for lateral flagella from those for polar flagella) is exclusively from class I and is in V. parahaemolyticus class I and II. Furthermore, the A. hydrophila flgAMNL cluster is not transcribed from the ?54/LafK-dependent promoter and does not contain class II genes. Here, we propose a gene transcriptional hierarchy for the A. hydrophila lateral flagella.

Wilhelms, Markus; Gonzalez, Victor; Merino, Susana

2013-01-01

67

Laterality and Dyslexia: A Critical View.  

ERIC Educational Resources Information Center

|Research is reviewed concerning the current state of knowledge about normal hemispheric specialization; distinctions among such terms as dominance, laterality, and lateralization; and models of abnormal cerebral organization in dyslexic children. The question of dyslexic subtypes is undertaken along such dimensions as handedness, eyedness, and…

Hiscock, Merrill; Kinsbourne, Marcel

1982-01-01

68

SENSOR DATA FUSION FOR LATERAL SAFE APPLICATIONS  

Microsoft Academic Search

This paper describes the algorithms that are being developed for the perception layer of the PReVENT subproject LATERAL SAFE. These algorithms aim at achieving a reliable representation of the objects and their kinematics, present at the lateral and rear field of the ego-vehicle. The work presented in this paper is within the fields of radar tracking, sensor network processing, image

Angelos Amditis; Nikolaos Floudas; Aris Polychronopoulos; Dirk Bank; Bas van den Broek; Fred Oechsle; DaimlerChrysler AG; Robert Bosch

69

Lateral Path Controller Design for Autonomous Airship  

Microsoft Academic Search

According to the path control problem for unmanned autonomous airship, the lateral path mathematic model was introduced based on the scheme of control system and a kind of lateral path design method of autonomous airship is proposed based on fuzzy logic and adaptive sliding mode control (ASMC). The movement model and dynamic model of autonomous airship is derived from considering

Guo Jian-guo; Zhou Jun

2010-01-01

70

Reversed lateral dominance in identical twins  

Microsoft Academic Search

The evidence from this study of 17 pairs of identical twins reveals that one twin is right dominant and the other left dominant in practically every case of the phi-test (a test based on the laterality of apparent movement in binocular perception). Such reversal on other tests of lateral dominance occurs but seldom, although an indication of reversal on both

E. T. Raney

1938-01-01

71

Arthroscopic Centralization of an Extruded Lateral Meniscus  

PubMed Central

Extrusion of the lateral meniscus has been reported after posterior root tear or radial tear, partial meniscectomy, and meniscoplasty of discoid meniscus. It has also been shown to be associated with the development of osteoarthritis. This technical note describes a new arthroscopic technique to centralize and stabilize the mid body of the lateral meniscus to restore and maintain the lateral meniscus function by repairing/preventing extrusion of the meniscus. A JuggerKnot Soft Anchor (Biomet, Warsaw, IN), loaded with a MaxBraid suture (Biomet), was placed on the lateral edge of the lateral tibial plateau, just anterior to the popliteal hiatus, through a midlateral portal. A Micro Suture Lasso Small Curve with Nitinol Wire Loop (Arthrex, Naples, FL) was used to pass 2 limbs of the MaxBraid suture through the meniscus at the margin between the meniscus and the capsule. Another anchor was inserted on the lateral edge of the lateral tibial plateau, 1 cm anterior to the first anchor, and the same procedure was repeated. The sutures were then tied by use of a self-locking sliding knot, achieving centralization and secure stabilization of the lateral meniscus.

Koga, Hideyuki; Muneta, Takeshi; Yagishita, Kazuyoshi; Watanabe, Toshifumi; Mochizuki, Tomoyuki; Horie, Masafumi; Nakamura, Tomomasa; Okawa, Atsushi; Sekiya, Ichiro

2012-01-01

72

Arthroscopic centralization of an extruded lateral meniscus.  

PubMed

Extrusion of the lateral meniscus has been reported after posterior root tear or radial tear, partial meniscectomy, and meniscoplasty of discoid meniscus. It has also been shown to be associated with the development of osteoarthritis. This technical note describes a new arthroscopic technique to centralize and stabilize the mid body of the lateral meniscus to restore and maintain the lateral meniscus function by repairing/preventing extrusion of the meniscus. A JuggerKnot Soft Anchor (Biomet, Warsaw, IN), loaded with a MaxBraid suture (Biomet), was placed on the lateral edge of the lateral tibial plateau, just anterior to the popliteal hiatus, through a midlateral portal. A Micro Suture Lasso Small Curve with Nitinol Wire Loop (Arthrex, Naples, FL) was used to pass 2 limbs of the MaxBraid suture through the meniscus at the margin between the meniscus and the capsule. Another anchor was inserted on the lateral edge of the lateral tibial plateau, 1 cm anterior to the first anchor, and the same procedure was repeated. The sutures were then tied by use of a self-locking sliding knot, achieving centralization and secure stabilization of the lateral meniscus. PMID:23766997

Koga, Hideyuki; Muneta, Takeshi; Yagishita, Kazuyoshi; Watanabe, Toshifumi; Mochizuki, Tomoyuki; Horie, Masafumi; Nakamura, Tomomasa; Okawa, Atsushi; Sekiya, Ichiro

2012-10-22

73

Loss and Grief in Later Life.  

ERIC Educational Resources Information Center

|This guide is designed to help readers understand loss and grief, and to sensitively respond to the grief of others. Although emphasis is on losses experienced in later life, most information is equally applicable to grief throughout adulthood. A section on understanding loss in later life lists a number of losses that are associated with aging.…

Washington State Univ., Pullman. Cooperative Extension Service.

74

Does lateral gas diffusion in leaves matter?  

Microsoft Academic Search

Photosynthesis depends on the diffusion of gaseous CO2 inside the leaf spaces from the stomatal entry point to the mesophyll cell walls. Although most research considers only the vertical diffusion from stomata on upper and\\/or leaf lower surfaces, some of the gas will diffuse in the lateral (paradermal) direction. The importance of lateral CO2 dif- fusion is reviewed, and the

JAMES I. L. MORISON; TRACY LAWSON

2007-01-01

75

REVOLUTA regulates meristem initiation at lateral positions  

Microsoft Academic Search

The first two authors contributed equally to this work. Summary While the shoot apical meristem (SAM) is indirectly responsible for the initiation of all above-ground postembryonic organs, in most plants the vast majority of these organs are directly initiated by lateral meristems. In Arabidopsis thaliana, the lateral meristems include flower meristems (FMs), which form on the flanks of the SAM,

Denichiro Otsuga; Bernadette DeGuzman; Michael J. Prigge; Gary N. Drews; Steven E. Clark

2001-01-01

76

CONTROL OF STABILITY DURING SLOPE LATERAL WALKING  

Microsoft Academic Search

Objectives: The purpose of this study was to investigate the centre of pressure (COP) trajectory in level and slope lateral walking. Hopefully the results will provide useful information on improving labors' working safety. Method: Five normal subjects participated in this study. The entire lateral walking cycle can be divided into two double support phases and two single support phases (right

Chien-Ju Lin; Lin-Hwa Wang; Yi-Wen Chang; Fong-Chin Su

77

Lateral Asymmetries in Infant Melody Perception.  

ERIC Educational Resources Information Center

|Two experiments investigated lateral asymmetries in eight-month-olds' perception of contour-altered and contour-preserved melody changes. Found that infants who heard a contour-altered change showed a left-ear advantage, whereas infants who heard a contour-preserved change showed a right-ear advantage. The pattern of lateralization for melody…

Balaban, Marie T.; Anderson, Linda M.; Wisniewski, Amy B.

1998-01-01

78

The anatomy of the lateral canthal tendon.  

PubMed

This report documents the anatomy of the lateral canthus using gross dissection, histologic examination, computed tomography, magnetic resonance imaging, and clinical measurement. Lateral canthal dissections of 16 cadaver orbits demonstrated a well-defined attachment of the tarsal plates to the orbital rim, averaging 10.6 mm in length and 10.2 mm in width at their insertion on Whitnall's tubercle, 1.5 mm behind the orbital rim and 9.7 mm inferior to the frontozygomatic suture. Histologic examination showed a band of dense fibrous tissue attached to the tarsal plates, with intermingled muscle fibers from the pretarsal orbicularis oculi muscle. A small pocket of fat was identified posterior to the orbital septum and anterior to the lateral canthal tendon. Clinical measurements of normal adults revealed 2 mm of lateral movement of the canthal angle during abduction, apparently caused by posterior fibrous attachments to the check ligament of the lateral rectus muscle. PMID:3566607

Gioia, V M; Linberg, J V; McCormick, S A

1987-04-01

79

Predicting language lateralization from gray matter  

PubMed Central

It has long been predicted that the degree to which language is lateralized to the left or right hemisphere might be reflected in the underlying brain anatomy. We investigated this relationship on a voxel by voxel basis across the whole brain using structural and functional MRI images from 86 healthy participants. Structural images were converted to gray matter probability images and language activation was assessed during naming and semantic decision. All images were spatially normalized to the same symmetrical template and lateralization images were generated by subtracting right from left hemisphere signal at each voxel. We show that the degree to which language was left or right lateralized was positively correlated with the degree to which gray matter density was lateralized. Post-hoc analyses revealed a general relationship between gray matter probability and BOLD signal. This is the first demonstration that structural brain scans can be used to predict language lateralization on a voxel by voxel basis in the normal healthy brain.

Josse, Goulven; Kherif, Ferath; Flandin, Guillaume; Seghier, Mohamed L; Price, Cathy J

2009-01-01

80

Captura de satélites durante a formação de Júpiter  

NASA Astrophysics Data System (ADS)

O planeta Jupiter apresenta um grande número de satélites irregulares. As características das órbitas destes objetos indicam que os mesmos não teriam se formado ao redor do planeta que se encontram. As teorias existentes são de que estes objetos teriam se formado em uma região distante do planeta e sua evolução dinâmica os teria levado a uma captura gravitacional pelo planeta. Tendo em vista que o processo de captura gravitacional sem efeitos dissipativos não produz uma captura permanente, estudamos o processo de captura durante o estágio de formação do planeta. Realizamos simulações numéricas para os casos de satélites prógrados e retrógrados que inicialmente se encontram ao redor de Jupiter com sua massa atual e então, evoluimos a integração voltando no tempo de modo que o planeta sofra uma redução em sua massa (de 100% para 10% de sua massa atual) e verificamos o instante em que o satélites escapa do planeta (quando sua energia do problema de dois corpos se torna positiva). Assim, analisando o problema inverso no tempo, obtivemos em qual estágio de formação de Jupiter aquele hipotético satélite teria sido capturado. Os resultados mostram que os satélites retrógrados são capturados assim que entram na região delimitada pela esfera de Hill do planeta, enquanto que os satélites prógrados só são capturados quando entram numa região bem mais próxima ao planeta, uma fração da esfera de Hill.

Winter, O. C.; Vieira Neto, E.; Yokoyama, T.

2003-08-01

81

Osteochondritis dissecans of the lateral femoral condyle following total resection of the discoid lateral meniscus  

Microsoft Academic Search

Purpose: The purpose of this study was to describe the clinical presentation of 6 athletically active children with symptomatic osteochondritis dissecans (OCD) of the lateral femoral condyle following total resection for a torn discoid lateral meniscus and to discuss its cause. Type of Study: Case series. Methods: Six patients in whom OCD affecting the lateral femoral condyle developed after total

Hiroshi Mizuta; Eiichi Nakamura; Yutaka Otsuka; Satoshi Kudo; Katsumasa Takagi

2001-01-01

82

Influence of lateral restraint on lateral-torsional buckling of cold-formed steel purlins  

Microsoft Academic Search

In this paper, the influence of the lateral restraint provided by cladding on the lateral-torsional buckling of zed-purlin beams is investigated in detail. The analysis is performed using the energy method. The influence of the lateral restraint on the critical load is discussed for beams with various different boundary conditions, loading positions, with and without interval anti-sag bars.

Xiao-ting Chu; Jamie Rickard; Long-yuan Li

2005-01-01

83

Lateral open bite: treatment and stability.  

PubMed

Because of their multifactorial etiologies, dental and skeletal open bites are among the most difficult malocclusions to treat to a successful and stable result. Etiologic factors include vertical maxillary excess, skeletal pattern, abnormalities in dental eruption, and tongue-thrust problems. The purpose of this article was to report the treatment of an adult patient with a lateral open bite and a unilateral posterior crossbite. The treatment involved nonextraction therapy, including intermaxillary elastics, to obtain dentoalveolar extrusion in the region of the lateral open bite. The treatment results were successful and remained stable 2 years later. PMID:20451792

Cabrera, Marise de Castro; Cabrera, Carlos Alberto Gregório; de Freitas, Karina Maria Salvatore; Janson, Guilherme; de Freitas, Marcos Roberto

2010-05-01

84

Dynamic Lateral Earth Pressure on Underground Structures.  

National Technical Information Service (NTIS)

The dynamic lateral earth pressures resulting from underground detonation can cause severe damage to underground structures. The shock exerted on an underground structure caused by an underground explosion will vary with the detonation depth, the intensit...

S. M. Helwany A. Chowdhury

2000-01-01

85

Lateral Transpsoas Fusion: Indications and Outcomes  

PubMed Central

Spinal fusion historically has been used extensively, and, recently, the lateral transpsoas approach to the thoracic and lumbar spine has become an increasingly common method to achieve fusion. Recent literature on this approach has elucidated its advantage over more traditional anterior and posterior approaches, which include a smaller tissue dissection, potentially lower blood loss, no need for an access surgeon, and a shorter hospital stay. Indications for the procedure have now expanded to include degenerative disc disease, spinal stenosis, degenerative scoliosis, nonunion, trauma, infection, and low-grade spondylolisthesis. Lateral interbody fusion has a similar if not lower rate of complications compared to traditional anterior and posterior approaches to interbody fusion. However, lateral interbody fusion has unique complications that include transient neurologic symptoms, motor deficits, and neural injuries that range from 1 to 60% in the literature. Additional studies are required to further evaluate and monitor the short- and long-term safety, efficacy, outcomes, and complications of lateral transpsoas procedures.

Patel, Vishal C.; Park, Daniel K.; Herkowitz, Harry N.

2012-01-01

86

33 CFR 62.25 - Lateral marks.  

Code of Federal Regulations, 2013 CFR

...route to be followed. They may be either beacons or buoys. (b) Sidemarks are lateral marks which...Buoyage. Beacons have green square daymarks, while buoys are green can or pillar buoys. (2) Starboard hand marks indicate the...

2013-07-01

87

Perception and a lateral inversion fallacy  

Microsoft Academic Search

A subtle misconception concerning the deceptively simple act of observation of reflection by a plane mirror is discussed and a fallacy regarding lateral inversion is analysed. In the analysis, visual perception is used as a metaphor of cognition in general.

E. C. Horsfield

1991-01-01

88

Reliability of the Lateral Dominance Examination.  

PubMed

The reliability of the Lateral Dominance Examination over a 5-year period was evaluated in 162 normal and neurologically impaired adults. Stability of individual test items was appraised as well as that of summary measures of handedness, eyedness, and footedness. Items evaluating handedness rendered highly consistent results with the most reliable item relating to hand used for writing (100%). Eyedness and footedness items were somewhat less reliable. While the data raised the possibility that non-right-handers may be slightly less consistent over time, membership in a neurological group, extent of impairment on neuropsychological tests, and gender were unrelated to consistency in lateral preference measurement. It is concluded that the Lateral Dominance Examination is a reliable measure of lateral preference. PMID:8491844

Dodrill, C B; Thoreson, N S

1993-03-01

89

Projectile Aerodynamic Jump Due to Lateral Impulsives.  

National Technical Information Service (NTIS)

The linear theory for spinning projectiles is extended to account for the application of a simple lateral square impulse activated during free flight. Analytical results are shown to produce simple contributions to the familiar aerodynamic jump formulatio...

G. R. Cooper

2003-01-01

90

Genetic Basis of Laterality, Reading, Mental Traits.  

National Technical Information Service (NTIS)

The genetic basis of laterality, reading, and mental traits were studied. The population of inquiry was the Hutterian Brethern of North America who constitute a literature, nonmobile group which does not practice birth control and has exhaustive geneologi...

D. Kolakowski

1982-01-01

91

Lateral attenuation of aircraft flight noise  

NASA Astrophysics Data System (ADS)

This report reviews models for calculating the lateral attenuation of aircraft flight noise, in particular, the change in attenuation for different elevation angles varying from aircraft directly overhead (90 deg. elevation angle) to a zero elevation angle. Sets of noise spectrum-dependent lateral attenuation values derived from theory and from experimental flight measurements were applied to sets of different aircraft noise spectra to determine A-level differences with elevation angle. The lateral attenuation based on the experimental data showed appreciably greater attenuation, but still less attenuation than the SAE model currently incorporated in the Integrated Noise Model (INM) aircraft noise computer program. Based on the experimental curves, a new generalized transition model was developed and is recommended as a replacement for current NOISEMAP lateral transition algorithm.

Bishop, D. E.

1985-03-01

92

Lateral transpsoas fusion: indications and outcomes.  

PubMed

Spinal fusion historically has been used extensively, and, recently, the lateral transpsoas approach to the thoracic and lumbar spine has become an increasingly common method to achieve fusion. Recent literature on this approach has elucidated its advantage over more traditional anterior and posterior approaches, which include a smaller tissue dissection, potentially lower blood loss, no need for an access surgeon, and a shorter hospital stay. Indications for the procedure have now expanded to include degenerative disc disease, spinal stenosis, degenerative scoliosis, nonunion, trauma, infection, and low-grade spondylolisthesis. Lateral interbody fusion has a similar if not lower rate of complications compared to traditional anterior and posterior approaches to interbody fusion. However, lateral interbody fusion has unique complications that include transient neurologic symptoms, motor deficits, and neural injuries that range from 1 to 60% in the literature. Additional studies are required to further evaluate and monitor the short- and long-term safety, efficacy, outcomes, and complications of lateral transpsoas procedures. PMID:23213303

Patel, Vishal C; Park, Daniel K; Herkowitz, Harry N

2012-11-06

93

Postural laterality in torticollis and torsion dystonia.  

PubMed Central

Tests of postural rotational laterality were carried out in 63 patients suffering from torticollis (53) or torsion dystonia with torticollis (10) and in 33 normal subjects. There was a correlation between the predominant direction of postural functions and the direction of the rotatory component of torticollis. Torticollis and torsion dystonia may be due to the release of a postural rotational laterality in pre-disposed subjects and not to a presumed asymmetric lesion of the brain-stem. Images

Stejskal, L; Tomanek, Z

1981-01-01

94

Auxin Induced Lateral Root Formation in Chicory  

Microsoft Academic Search

The supply of auxins [2,4-dichlorophenoxy acetic acid (2,4D), indole-3 acetic acid (1AA) and ?-naphthaleneacetic acid (NAA)] to excised chicory roots induced the formation of lateral root meristems mainly located close to the pre-existing apical root meristem. Lateral root growth induced in non-excised roots required higher auxin concentrations. Inhibition of root elongation and concomittant enlargement of the apices was also observed.

CHRISTOPHE VUYLSTEKER; ERIC DEWAELE; SERGE RAMBOUR

1998-01-01

95

Adolescent Sexual Debut and Later Delinquency  

Microsoft Academic Search

Does sexual debut (i.e., experiencing sexual intercourse for the first time) increase the risks of participating in later\\u000a delinquent behavior? Does this risk increase if adolescents experience early sexual debut relative to the timing experienced\\u000a by one’s peers? Although many factors have been linked to sexual debut, little research has examined whether sexual initiation\\u000a is linked to later behavioral outcomes.

Stacy Armour; Dana L. Haynie

2007-01-01

96

Task-specific initial impact phase adjustments in lateral jumps and lateral landings.  

PubMed

Load-dependant adjustments in lateral jumps are thought to rely on foot placement and on upper leg's kinematic and neuromuscular adaptations. The aim of this study was to elucidate task-specific adjustments during the initial impact phase under varying stretch-loads by the comparison of lateral jumps and lateral landings. Ten subjects performed lateral jumps and landings from four distances. Electromyographic (EMG) data of five lower extremity muscles were measured, whilst lower extremity kinematics and kinetics were analysed by 3D motion analysis. Lateral jumps were characterized by increased impact forces, higher lower extremity joint moments with exception of the initial knee abduction moment, greater sagittal knee and hip joint displacements, and a further exorotated foot placement. In lateral landings frontal ankle and hip joint displacements were greater. Thigh muscle and m. tibialis anterior (TA) pre-activity as well as initial post-impact EMG were higher in lateral jumps than in lateral landings, whilst during the reflex-induced phase thigh and shank muscle EMG, except for TA, were enhanced in lateral jumps. From these findings it can be concluded that task specificity in lateral jumps in contrast to lateral landings impedes a stretch-load adequate modulation of initial impact forces which particularly affects ankle joint loading. Foot placement seems to play a decisive role for limiting lateral ankle and medial knee joint loading. Therefore, in sports containing high-impact frontal plane movements a special emphasis in training routines should be paid to foot placement strategy in those movements. Such training interventions might contribute to injury prevention in lateral movements. PMID:21336953

Fleischmann, Jana; Gehring, Dominic; Mornieux, Guillaume; Gollhofer, Albert

2011-02-20

97

Motoric indicators of laterality and determination of lateral dominance in schizophrenia.  

PubMed

The literature suggests that schizophrenics exhibit reduced or reversed cerebral lateral dominance relative to normal control subjects. An hypothesis which predicted reduced or reversed cerebral laterality for schizophrenics was tested on 60 young, familially right-handed males, with 20 men in each of the following three groups: schizophrenic inpatients, nonschizophrenic psychiatric inpatient controls, and normal controls. The subjects were administered a battery of seven measures of cerebral laterality. The application of multivariate statistical techniques showed groups did not differ significantly in the degree or the direction of their cerebral lateral dominance. Also there were no significant correlations between the measures of laterality. The findings suggest that cerebral lateral dominance is not necessarily altered concomitantly with psychopathology but rather that it is a complex phenomenon which may not be reliably determined on the basis of simple behavioral characteristics. PMID:4022743

Scott, D G

1985-06-01

98

Predicting language lateralization from gray matter.  

PubMed

It has long been predicted that the degree to which language is lateralized to the left or right hemisphere might be reflected in the underlying brain anatomy. We investigated this relationship on a voxel-by-voxel basis across the whole brain using structural and functional magnetic resonance images from 86 healthy participants. Structural images were converted to gray matter probability images, and language activation was assessed during naming and semantic decision. All images were spatially normalized to the same symmetrical template, and lateralization images were generated by subtracting right from left hemisphere signal at each voxel. We show that the degree to which language was left or right lateralized was positively correlated with the degree to which gray matter density was lateralized. Post hoc analyses revealed a general relationship between gray matter probability and blood oxygenation level-dependent signal. This is the first demonstration that structural brain scans can be used to predict language lateralization on a voxel-by-voxel basis in the normal healthy brain. PMID:19864564

Josse, Goulven; Kherif, Ferath; Flandin, Guillaume; Seghier, Mohamed L; Price, Cathy J

2009-10-28

99

Lateral organization of the postsynaptic density  

PubMed Central

Fast excitatory synaptic transmission is mediated by AMPA-type glutamate receptors (AMPARs). It is widely accepted that the number of AMPARs in the postsynaptic density (PSD) critically determines the efficiency of synaptic transmission, but an unappreciated aspect of synapse organization is the lateral positioning of AMPARs within the PSD, that is, their distribution across the face of a single synapse. Receptor lateral positioning is important in a number of processes, most notably because alignment with presynaptic release sites heavily influences the probability of receptor activation. In this review, we summarize current understanding of the mechanisms that dynamically control the subsynaptic positioning of AMPARs. This field is still at early stages, but the recent wave of developments in super-resolution microscopy, synapse tomography, and computational modeling now enable the study of lateral protein distribution and dynamics within the nanometer-scale boundaries of the PSD. We discuss data available measuring the lateral distribution of glutamate receptors and scaffold proteins within the PSD, and discuss potential mechanisms that might give rise to these patterns. Elucidating the mechanisms that underlie the lateral organization of the PSD will be critical to improve our understanding of synaptic processes whose disruption may be unexpectedly important in neurological disorders.

MacGillavry, Harold D.; Kerr, Justin M.; Blanpied, Thomas A.

2011-01-01

100

Evaluation and management of lateral ankle injuries.  

PubMed

The diagnosis and management of lateral ankle injuries require the physician to obtain an accurate history, complete a thorough physical examination, and institute appropriate treatment protocol. Labeling all acute lateral ankle injuries as ankle sprains can lead to long-term mechanical and functional instability and chronic pain around the ankle. Appropriate and aggressive functional rehabilitation of the acute ankle limits the postinjury convalescence and need for surgical reconstruction. If surgical repair of the chronic or acute ankle is warranted, the Brostrom-Gould procedure serves as a highly successful anatomic repair. Lateral ankle tenodesing procedures also are effective; however, in most cases, the loss of rearfoot motion limits this procedure to a secondary reconstructive procedure. PMID:10553227

Lee, M S; Hofbauer, M H

1999-10-01

101

[Fractures of the lateral clavicle and acromion].  

PubMed

Fractures of the lateral clavicle and the acromion are uncommon and represent a separate entity. Fractures of the lateral clavicle demonstrate a high rate of problems, such as non-union, malunion and functional impairment when treated nonoperatively. The aim of any treatment option is full restoration of shoulder function by achieving fracture healing without significant malpositioning. Unstable fracture patterns have to be identified and should be fixed using an appropriate technique, which include plating, K-wire fixation and arthroscopic techniques which bring the dislocated fragments into contact. Dislocated fractures of the acromion can usually be treated by plating. PMID:23007124

Meller, R; Krettek, C

2012-10-01

102

Dynamically stabilized lateral patterns in changed blends  

NASA Astrophysics Data System (ADS)

We investigate a thin film consisting of a symmetric melt blend of oppositely charged, yet thermodynamically incompatible polymers. In the absence of an externally applied electric field, microsegregation occurs in this system forming alternating layers of charged material resembling structures formed in layer-by-layer deposition of polyelectrolyte films. However, when subjected to an oscillating electric field aligned along the film normal, lateral striped microsegregation patterns are stabilized. In addition to a linear stability analysis, we present numerical simulation results on the development of the lateral ordering.

Solis, Francisco J.; Pickett, Galen T.

2004-03-01

103

Neonatal behavioral characteristics and later behavioral problems.  

PubMed

The purposes of this study were (1) to evaluate the usefulness of the Neonatal Behavioral Assessment Scale (NBAS) as a tool to assess the risk of later behavioral problems, (2) to analyze the relationship between neonatal behavioral characteristics and behavioral problems in childhood. Subjects were 77 very-low-birth-weight infants admitted to the NICU at the Nagasaki University Hospital, Nagasaki, Japan. The results suggest that behavioral characteristics such as poor motor performance, poor state regulation, and poor interaction ability in the neonatal period are risk factors for behavioral problems in childhood. The NBAS could help clinicians to identify neonates at risk of later behavioral problems. PMID:14601916

Ohgi, Shohei; Takahashi, Tatsuya; Nugent, J Kevin; Arisawa, Kokichi; Akiyama, Tomitaro

2003-10-01

104

Supernumerary auricle on the lateral canthus.  

PubMed

A boy was born with an appendage on his right lateral canthus, with associated supernumerary auricles on the right cheek and a right ocular dermoid. We resected the appendage. Its core was composed of elastic cartilage, as is the external auricle. The lateral canthus overlaps facial cleft line No. 8 in Tessier's classification [Plast Reconstr Surg 4 (1976) 69] and forms the upper part of the first branchial arch. It appears that our patient's appendage was a supernumerary auricle, which had developed from the first branchial arch. PMID:15544783

Shimizu, F; Nishimoto, S; Oyama, T

2004-12-01

105

Lateral epicondylalgia: a musculoskeletal physiotherapy perspective  

Microsoft Academic Search

Tennis elbow or lateral epicondylalgia (LE) is a challenging musculoskeletal condition to treat. This is largely due to the lack of research-based evidence of the clinical efficacy of the myriad of treatment approaches espoused in the literature. In view of this, successful rehabilitation of LE is based on choosing treatments that address the physical impairments found during clinical examination. The

B. Vicenzino

2003-01-01

106

Gender Differences in Lateralized Semantic Priming  

Microsoft Academic Search

Previous literature suggests that women evidence more bilateral cerebral organization, particularly in language processing, whereas men show greater left hemisphere dominance for language. This study examined the magnitude of these gender differences in a lateralized lexical decision task and the implications of such differences to semantic processing and cerebral organization. As predicted, women, as compared to men, recruited greater bilateral

Sarah A. Van Dyke; Virginia Zuverza; Laura A. Hill; Justin B. Miller; Lisa J. Rapport; R. Douglas Whitman

2009-01-01

107

Pain sensitivity, cerebral laterality, and negative affect  

Microsoft Academic Search

The right hemisphere is assumed to play a unique role for pain sensitivity and negative affect. Pressure pain thresholds were assessed daily in eight right-handed participants over a 6-week period in order to obtain reliable measures of pain sensitivity unaffected by situational influences. In an additional session, cerebral laterality was assessed with behavioral and an EEG measures. Psychometric measures were

Paul Pauli; Georg Wiedemann; Matthias Nickola

1999-01-01

108

Lateral Biases in Assumptions of Lighting Position  

ERIC Educational Resources Information Center

People presume that the light source in pictures comes from above, and there is some evidence that this phenomenon also demonstrates lateral biases. When investigators present multiple ambiguous stimuli or visually complex objects, people assume that the source of light is from above, and to the left. However, when single relatively simple stimuli…

Elias, Lorin J.; Robinson, Brent M.

2005-01-01

109

Nanodiamond Lateral VFEM Technology for Harsh Environments  

Microsoft Academic Search

This paper reports the first total dose tests on a nanocrystalline diamond lateral vacuum field emission microelectronics (VFEM) technology. This technology operates efficiently at both low and high temperatures (200degC) and is inherently ldquohardrdquo to radiation. No measurable change in device response is observed after 15 Mrad(SiO2) total dose exposure, signifying an emerging electronics for extreme environment.

W. P. Kang; J. L. Davidson; K. Subramanian; B. K. Choi; K. F. Galloway

2007-01-01

110

49 CFR 229.63 - Lateral motion.  

Code of Federal Regulations, 2012 CFR

...wheels and boxes, between boxes and pedestals or both, on any pair of wheels may not exceed 1 inch on non-powered axles and friction bearing powered axles, or 3/4 inch on all other powered axles. (b) The total uncontrolled lateral motion may...

2012-10-01

111

49 CFR 229.63 - Lateral motion.  

Code of Federal Regulations, 2011 CFR

...wheels and boxes, between boxes and pedestals or both, on any pair of wheels may not exceed 1 inch on non-powered axles and friction bearing powered axles, or 3/4 inch on all other powered axles. (b) The total uncontrolled lateral motion may...

2011-10-01

112

Alexithymia, Hemisphericity, and Conjugate Lateral Eye Movements  

Microsoft Academic Search

The conjugate lateral eye movements (CLEMs) of 102 university students were measured in conjunction with the administration of the Schalling-Sifneos Personality Scale, a self-report measure of alexithymia. There was a significant positive correlation beween CLEM scores and alexithymia scores for all subjects, suggesting the existence of a relationship between right hemishpere activation and alexithymic characteristics. These results are discussed in

Gordon Cole; Paul Bakan

1985-01-01

113

Cerebral Lateralities and Individualized Instruction. Final Report.  

ERIC Educational Resources Information Center

|To ascertain whether cerebral lateralities can be considered aptitudes or individual difference measures within an aptitude-treatment-interaction (ATI) framework, hemispheric asymmetries and cognitive psychometric tests were administered to 50 right-handed, Caucasian, male Navy recruits. Principal factor analysis with varimax rotation was…

Federico, Pat-Anthony

114

Human Greater and Canine Lateral Saphenous Veins  

Microsoft Academic Search

Canine lateral saphenous vein and human greater saphenous vein were studied together to determine similarities and differences. Helical strips of both vessels contracted to norepinephrine with similar sensitivity. Canine veins developed more isometric tension than human veins treated similarly. Histological studies show canine veins to have little connective tissue and a single circular layer of smooth muscle. Human veins have

Michael R. Goldberg; Paul D. Joiner; Albert L. Hyman; Philip J. Kadowitz

1975-01-01

115

Motor laterality in 4 breeds of dog  

Microsoft Academic Search

The aim of the current study was designed to explore possible breed differences in a basic behavioral phenotype in dogs. It measured paw use during food-retrieval from a cylindrical, hollow, rubber toy to assess motor laterality (pawedness) in 4 breeds of dogs selected for their morphological differences: 45 greyhounds (males n = 23\\/females n = 22), 47 whippets (15\\/32), 46

Paul D. McGreevy; Alex Brueckner; Peter C. Thomson; Nicholas J. Branson

2010-01-01

116

Lateral Stability of Towed Flexible Vehicles  

Microsoft Academic Search

The highway transport of mobile homes is a matter of concern for the increasingly safety-minded driving public. The low speeds of towed vehicles necessary to maintain stability, together with the requirements for excessive lane widths due to clearance for the lateral motion, result in increased likelihood of traffic accidents, impeded traffic flow, and reduced highway capacity. A safe increase in

Jeries ABOU-HANNA; Charles R. EVCES; James L. HILL

1988-01-01

117

Lateral Dominance, Pain Perception, and Pain Tolerance  

Microsoft Academic Search

It has been suggested that lateral dominance influences pain perception and pain tolerance ; but when electric stimulation was used on human teeth, there appeared to be no difference in the pain perception threshold values on each side of the midline. Pain tolerance values seem to support the suggestion, but the results were not statistically significant.

A. V. Newton; J. M. Mumford

1972-01-01

118

Lateralization of cognitive processes in the brain  

Microsoft Academic Search

The lateralization of cognitive processes in the brain is discussed. The traditional view of a language-visuo\\/spatial dichotomy of function between the hemispheres has been replaced by more subtle distinctions. The use of magnetic resonance imaging (MRI) to study brain morphology has resulted in a renewed focus on the relationship between structural and functional asymmetry. Focus has been on the role

Kenneth Hugdahl

2000-01-01

119

Reliability of the Lateral Dominance Examination  

Microsoft Academic Search

The reliability of the Lateral Dominance Examination over a 5-year period was evaluated in 162 normal and neurologically impaired adults. Stability of individual test items was appraised as well as that of summary measures of handedness, eyedness, and footedness. Items evaluating handedness rendered highly consistent results with the most reliable item relating to hand used for writing (100%). Eyedness and

Carl B. Dodrill; Nathaniel S. Thoreson

1993-01-01

120

Microscopic histopathology of chronic refractory lateral epicondylitis  

Microsoft Academic Search

The histopathologic features from 11 patients who were treated surgically for lateral epicondylitis were graded and compared to similar tissue from 12 cadaveric spec imens. All studies were done by a single pathologist who had no knowledge of the origin of the specimen. The surgical specimens were interpreted as abnormal in all 11 specimens, and all 12 of the control

William Regan; Lester E. Wold; Ralph Coonrad; Bernard F. Morrey

1992-01-01

121

Depression in Later Life: Recognition and Treatment.  

ERIC Educational Resources Information Center

|This guide is designed to help readers understand depression and factors related to its onset in later life; recognize signs of depression and potential suicide; and know actions they can take if they suspect an older family member or friend may be depressed or contemplating suicide. Following a brief introduction, a chapter on depression…

Schmall, Vicki L.; And Others

122

Active Children: Healthy Now And Later  

ERIC Educational Resources Information Center

|Current research is revealing that physical activity can protect against a range of lifestyle diseases and illnesses. Consequently, early childhood practitioners and parents need to adopt guidelines and practices which encourage children of all ages to be physically active. In "Active children: Healthy Now and Later," authors Linley Campbell and…

Campbell, Linley; Musumeci, Josephine

2005-01-01

123

Lateral Shock of the R Aquarii Jet.  

National Technical Information Service (NTIS)

The R Aqr jet was observed with the VLA B-configuration at two epochs separated by approximately 13.2 yr. Comparison of the resulting 6 cm continuum images show that the radio jet has undergone a lateral counterclockwise rotation of approximately 6 deg-12...

J. M. Hollis J. A. Pedelty M. Kafatos

1997-01-01

124

Teachers Guides to Television: "Sooner or Later."  

ERIC Educational Resources Information Center

|Presents a teacher's guide to the study of the television program, "Sooner or Later," which is a drama dealing with concerns of love and interpersonal relationships among adolescents. Related multimedia instructional materials available for parent participation in television workshops are described. (CMV)|

Audiovisual Instruction, 1979

1979-01-01

125

Lateralization of Norepinephrine in Human Thalamus  

Microsoft Academic Search

Norepinephrine has a strongly lateralized distribution in the human thalamus. In the pulvinar region the left hemisphere is rich in norepinephrine, whereas in the somatosensory input area the right hemisphere has a higher concentration of this catecholamine. Such naturally occurring left-right differences in concentration of a neurotransmitter represent a new aspect of hemispheric specialization.

Arvin Oke; Richard Keller; Ivan Mefford; Ralph N. Adams

1978-01-01

126

Lateral capacity of helical piles in clays  

SciTech Connect

Helical piles, also known as screw anchors, consist of one or more helical-shaped circular plates welded to a central steel shaft at a specified spacing. Currently, helical piles are being used as tower foundations on land and in offshore areas to secure moorings, cables, and sea-bed pipelines to the sea bed. In this paper, the behavior of helical piles under lateral loads in clayey soils is examined through an experimental investigation on model piles. Tests were conducted on rigid helical piles with different numbers of plates. Model anchors were made of 13.8 mm diameter mild steel shafts to which mild steel plates of 33 mm diameter were welded. For comparison, a single straight shaft with a diameter of 13.8 mm was also tested. Test results revealed that the lateral capacity of helical piles is greater than that of straight shaft piles. A simple theoretical model is suggested to estimate the lateral capacity of rigid helical piles. The theoretical model suggested incorporates lateral resistance of the soil on the shaft, bearing resistance on the bottom of the helical plate, uplift resistance on the top of the helical plate, and frictional resistance on the surface of the helical plate. The validity of this model is examined.

Prasad, Y.V.S.N. [Memorial Univ. of Newfoundland, St. John`s, Newfoundland (Canada). Faculty of Engineering and Applied Science

1996-11-01

127

Lateral root organogenesis - from cell to organ.  

PubMed

Unlike locomotive organisms capable of actively approaching essential resources, sessile plants must efficiently exploit their habitat for water and nutrients. This involves root-mediated underground interactions allowing plants to adapt to soils of diverse qualities. The root system of plants is a dynamic structure that modulates primary root growth and root branching by continuous integration of environmental inputs, such as nutrition availability, soil aeration, humidity, or salinity. Root branching is an extremely flexible means to rapidly adjust the overall surface of the root system and plants have evolved efficient control mechanisms, including, firstly initiation, when and where to start lateral root formation; secondly lateral root primordia organogenesis, during which the development of primordia can be arrested for a certain time; and thirdly lateral root emergence. Our review will focus on the most recent advances in understanding the molecular mechanisms involved in the regulation of lateral root initiation and organogenesis with the main focus on root system of the model plant Arabidopsis thaliana. PMID:20934368

Benková, Eva; Bielach, Agnieszka

2010-10-08

128

Autosomal dominant juvenile amyotrophic lateral sclerosis  

Microsoft Academic Search

Summary Juvenile amyotrophic lateral sclerosis (ALS) is a form of chronic motor neuron disease characterized by combined upper and lower motor neuron symptoms and signs with onset prior to age 25 years. We report the clinical and electrodiagnostic findings in 49 affected family members and neuropathological findings from two autopsies of a Maryland kindred with autosomal dominant juvenile ALS linked

Bruce A. Rabin; John W. Griffin; Barbara J. Crain; Mena Scavina; Philip F. Chance; David R. Cornblath

1999-01-01

129

CMOS–MEMS Lateral Electrothermal Actuators  

Microsoft Academic Search

In this paper, a type of lateral electrothermal (ET) actuator fabricated with post-CMOS micromachining is presented. The actuator is a beam with a multimorph structure, composed of CMOS dielectric and metal interconnect. Following structural release, the actuators demonstrate self-assembly under the moments arising from residual stress. Actuation is achieved through the imbalanced thermal expansion of internal interconnect members, whose relative

Peter J. Gilgunn; Jingwei Liu; Niladri Sarkar; Gary K. Fedder

2008-01-01

130

Pseudoaneurysm of the Lateral Circumflex Femoral Artery  

Microsoft Academic Search

We describe an unusual case of pseudo-aneurysm of the lateral circumflex femoral artery following fixation of an undisplaced\\u000a intracapsular neck of femur fracture. We highlight the need for a high index of suspicion and the value of angiography as\\u000a the investigation of choice.

Gopikrishna K. Kakarala; Lee Van Rensburg; Martyn Parker

2006-01-01

131

North Korea: Carrots Now, Sticks Later.  

National Technical Information Service (NTIS)

In Book One of Clausewitz's 'On War', he writes, 'In war the result is never final. The defeated state often considers the outcome merely as a transitory evil, for which a remedy may be found in political conditions at some later date. The state of relati...

C. C. Romig

2003-01-01

132

The Columbine Tragedy Ten Years Later  

ERIC Educational Resources Information Center

|Some tragedies are so emblazoned in people's minds that years later they can recall where they were when they first heard the news. The assassinations of John F. Kennedy and Martin Luther King Jr., the Challenger explosion, and the Sept. 11 terrorist attacks are among these events. So also is the Columbine High School tragedy of April 20, 1999.…

Hammond, Jane

2009-01-01

133

Lateral buttock congenital dermal sinus tract.  

PubMed

A 6-month-old female presented with purulent discharge from a dimple in the right lateral buttock. A subcutaneous abscess was palpated on the right paravertebral region at the L5-S1 level. She had low-grade fever with laboratory findings of leukocytosis and elevation of C-reactive protein levels. Klebsiella and Enterococcus species were cultured from the pus. Computed tomography (CT) clearly showed a tract traversing the subcutaneous tissue and connecting to the abscess. Magnetic resonance (MR) imaging showed no abnormality in the spinal canal. The diagnosis was infected congenital dermal sinus (CDS) in the right buttock. After normalization of body temperature and laboratory findings in response to antibiotic treatment, the dermal sinus tract was surgically removed. Intraoperative findings showed that the tract gradually tapered and ended at the subcutaneous abscess space over the lumbosacral fascia. Histological examination confirmed the lesion was dermal sinus. Although laterally placed CDS in the buttocks is extremely rare with only 5 previous cases reported, lateral CDS should be included in the differential diagnosis of a dimple in the buttocks. CT as well as MR imaging should be performed to evaluate suspected lateral CDS. PMID:21701114

Yamaguchi, Satoshi; Takeda, Masaaki; Kihara, Hirotaka; Eguchi, Kuniki; Mitsuhara, Takafumi; Matsushige, Toshinori; Kurisu, Kaoru

2011-01-01

134

Lateralized Temporal Order Judgement in Dyslexia  

ERIC Educational Resources Information Center

|Temporal and spatial attentional deficits in dyslexia were investigated using a lateralized visual temporal order judgment (TOJ) paradigm that allowed both sensitivity to temporal order and spatial attentional bias to be measured. Findings indicate that adult participants with a positive screen for dyslexia were significantly less sensitive to…

Liddle, Elizabeth B.; Jackson, Georgina M.; Rorden, Chris; Jackson, Stephen R.

2009-01-01

135

Childhood Victimization; Early Adversity, Later Psychopathology.  

National Technical Information Service (NTIS)

Childhood physical abuse, sexual abuse, and neglect have both immediate and long-term effects. Different types of abuse have a range of consequences for a childs later physical and psychological well-being, cognitive development, and behavior. But there i...

C. S. Widom

2000-01-01

136

Lateral tensioning system for riser pipe  

SciTech Connect

A novel way is described of maintaining a riser in the approximate center of a moon pool of a drilling barge operating in a shallow water. A single hydropneumatic cylinder is used to support the riser from the barge laterally at four points using a series of cables, sheaves, and a load cell.

Kolpak, M.M.

1980-11-04

137

Regulation of Social Relationships in Later Adulthood  

Microsoft Academic Search

Individuals are seen as coproducers of their social environments who actively manage the social resources that contribute to their positive aging. The regulation of social relationships reflects adaptive mechanisms of deliber- ate acquisition, maintenance, transformation, or discontinuation of relationships within the individual's personal network. Mechanisms of relationship regulation in later life are illustrated on the individual level with recent em-

Frieder R. Lang

2001-01-01

138

Cognitive Style and Lateral Eye Movements  

ERIC Educational Resources Information Center

|The lateral eye movement paradigm was employed to test the hypothesis that narrow categorizers, who are believed to be more analytic in information processing, make characteristic use of the left hemisphere, while broad categorizers, being more holistic, depend more on the right hemisphere. Results are discussed in terms of cerebral…

Huang, Ming-Shiunn; Byrne, Brian

1978-01-01

139

Lateral Eye Movement Behavior in Children.  

ERIC Educational Resources Information Center

|The conjugate lateral eye movement phenomenon was investigated for 52 children aged 2 through 10 using both spatial and verbal-analytic questions. The phenomenon was observed in 50 subjects and appeared well-established by age 3 1/2. Some interesting developmental findings and discrepancies with the results of adult studies are noted.…

Reynolds, Cecil R.; Kaufman, Alan S.

1980-01-01

140

The lateral hypothalamic area revisited: Ingestive behavior  

Microsoft Academic Search

This article discusses the role of the lateral hypothalamic area (LHA) in feeding and drinking and draws on data obtained from lesion and stimulation studies and neurochemical and electrophysiological manipulations of the area. The LHA is involved in catecholaminergic and serotonergic feeding systems and plays a role in circadian feeding, sex differences in feeding and spontaneous activity. This article discusses

Lee L. Bernardis; Larry L. Bellinger

1996-01-01

141

Fuzzy logic control for lateral vehicle guidance  

Microsoft Academic Search

A fuzzy logic controller (FLC) is designed and implemented in real time on a Toyota Celica test vehicle to achieve control of the lateral motion of the vehicle. The structure of FLC is modularized as feedback, preview, and gain scheduling rule bases. The parameters of FLC are tuned manually using information from the characteristics of human driving operation and existing

Thomas Hessburg; Masayoshi Tomizuka

1994-01-01

142

An Adaptive Lateral Preview Driver Model  

Microsoft Academic Search

SUMMARY Successful modeling and simulation of driver behavior is important for the current industrial thrust of computer-based vehicle development. The main contribution of this paper is the development of an adaptive lateral preview human driver model. This driver model template has a few parameters that can be adjusted to simulate steering actions of human drivers with different driving styles. In

Y. Ungoren; Huei Peng

2004-01-01

143

Oculomotor nuclear pathology in amyotrophic lateral sclerosis  

Microsoft Academic Search

We examined the oculomotor and\\/or trochlear nuclei of 27 amytrophic lateral sclerosis (ALS) patients and 10 controls by histological and immunohistological methods. Their neurons were relatively well preserved. In 7 of 22 sporadic ALS patients (including 3\\/3 ALS with ophthalmoplegia) and in 4 of 5 ALS patients with dementia, some morphological changes similar to those in anterior horns (Bunina bodies,

Koichi Okamoto; Shunsaku Hirai; Masakuni Amari; Tomomichi Iizuka; Mitsunori Watanabe; Nobuyuki Murakami; Masamitsu Takatama

1993-01-01

144

Biphasic cell responses on laterally mobile films  

NASA Astrophysics Data System (ADS)

The engineering of polymer surfaces or matrices that are capable of controlling cell adhesion has been widely explored. In nearly all of these works, the polymer chains (and ligands) are chemically attached to the underlying substrate, and therefore these systems are inherently static. By contrast, cellular environments such as the extracellular matrix (ECM) are dynamic and remodeled by biochemical reactions and biophysical forces. Borrowing this concept from Nature, we created polymer films by an interfacial self-assembly process, whereby individual chains can exhibit lateral mobility (in-plane diffusive motion). NIH 3T3 fibroblasts seeded on such RGD-presenting polymer films show biphasic responses in spreading and adhesion strength to lateral mobility, with a minimal response for intermediate mobility values. Futhermore, preliminary immuno-staining experiments reveal that the total area of focal adhesions demonstrates a similar biphasic trend to the cellular-scale behaviors. In contrast, actin filaments or stress fibers appear to be unaffected by the substrate lateral mobility. These results show that lateral mobility is an important, although not fully explored aspect of mechano-sensing by cells, and can potentially give new perspectives on cell-ECM interactions.

Kourouklis, Andreas; Lerum, Ronald; Bermudez, Harry

2013-03-01

145

Electroencephalographic laterality changes during human sexual orgasm  

Microsoft Academic Search

Left and right parietal EEGs were recorded while seven subjects experienced sexual climax through self-stimulation. EEG data were quantified by continuous cumulated measurements of the integrated areas of EEG recording during successive 1-sec epochs. In eight out of 12 experiments, this measure revealed a statistically significant change in laterality. Controlled replications with two of the original subjects obviated the possibility

Harvey D. Cohen; Raymond C. Rosen; Leonide Goldstein

1976-01-01

146

Lateral DMOS design for ESD robustness  

Microsoft Academic Search

This paper presents the design of efficient ESD protection in lateral DMOS (LDMOS) power transistor. Using characterization of the LDMOS transistor under ESD conditions with various gate and drain clamps, the design for minimum power dissipation is established. The results show that for ESD regime of pulses the channel heating effects are minimum and that optimum ESD level can be

Charvaka Duvvury; Fred Carvajal; Clif Jones; David Briggs

1997-01-01

147

Eccentric Strengthening for Chronic Lateral Epicondylosis  

PubMed Central

Background: Effective treatments for chronic lateral epicondylosis have not been studied adequately. Eccentric overload exercises have been used with success for other chronic tendinopathy, mainly Achilles and patellar. Hypothesis/Purpose: To compare a wrist extensor eccentric strengthening exercise program with a wrist extensor stretching/modality program for the treatment of chronic lateral epicondylosis. The authors hypothesized that the eccentric strengthening program would produce more favorable results than a stretching/modality program. Study Design: Prospective randomized controlled trial. Methods: Twenty-eight adults with lateral epicondylosis of greater than 4 weeks’ duration were randomized to an eccentric strengthening group or a stretching group. Exercises were taught by a physical therapist, and participants performed most of the exercises on their own at home. Pain scores with visual analog scale from 0 to 100 were obtained at baseline and then at 4, 8, 12, 16, and 20 weeks after the start of the exercise program. Results: Both groups improved their pain scores from baseline to the 4-week time point, followed by nonsignificant further decreases in pain scores thereafter. No statistically significant differences were found between the eccentric strengthening group and stretching groups at any follow-up time point. Conclusions: Despite previous reports documenting favorable results with eccentric exercises for other tendinopathy, the authors were unable to show any statistical advantage to eccentric exercises for lateral epicondylosis during these periods compared with local modalities and stretching exercises.

Wen, Dennis Y.; Schultz, Brian J.; Schaal, Bob; Graham, Scott T.; Kim, Byung Sung

2011-01-01

148

Preparing Future Faculty: Ten Years Later  

ERIC Educational Resources Information Center

When Sean Murphy designed the Graduate Student Internship Program at the College of Lake County (CLC), his 2001 TETYC article about the then two-year-old program detailed his programmatic response to the job market. Ten years later, the CLC-DePaul University partnership remains the strongest of the original dozen cross-sector relationships CLC…

Murphy, Sean P.; Aiossa, Elizabeth; Winter, Mary Mugica

2010-01-01

149

Lateralizing signs during seizures in focal epilepsy.  

PubMed

This article reviews lateralizing semiological signs during epileptic seizures with respect to prediction of the side of the epileptogenic zone and, therefore, presurgical diagnostic value. The lateralizing significance of semiological signs and symptoms can frequently be concluded from knowledge of the cortical representation. Visual, auditory, painful, and autonomic auras, as well as ictal motor manifestations, e.g., version, clonic and tonic activity, unilateral epileptic spasms, dystonic posturing and unilateral automatisms, automatisms with preserved responsiveness, ictal spitting and vomiting, emotional facial asymmetry, unilateral eye blinking, ictal nystagmus, and akinesia, have been shown to have lateralizing value. Furthermore, ictal language manifestations and postictal features, such as Todd's palsy, postictal aphasia, postictal nosewiping, postictal memory dysfunction, as well as peri-ictal water drinking, peri-ictal headache, and ipsilateral tongue biting, are reviewed. Knowledge and recognition of semiological lateralizing signs during seizures is an important component of the presurgical evaluation of epilepsy surgery candidates and adds further information to video/EEG monitoring, neuroimaging, functional mapping, and neuropsychological evaluation. PMID:15975856

Loddenkemper, Tobias; Kotagal, Prakash

2005-08-01

150

The Waiting Servant in Later Roman Art  

Microsoft Academic Search

Although literary sources from the early Empire attest to the importance attached to the presence of a large staff of specialized servants at the banquets of the wealthy, in the art of this period little emphasis is placed upon the servants in banquet scenes, who serve essentially utilitarian functions. By the later Empire, however, figures of attendants bearing offerings become

Katherine M. D. Dunbabin

2003-01-01

151

Terapia manual en epicondalgia lateral (revisión sistemática)  

Microsoft Academic Search

Lateral epicondylalgia (LE), or tennis elbow, is a musculoskeletal disorder that is difficult to treat due to the poor evidence base for intervention measures. The success of LE rehabilitation is based on clinical experience and on the treatment of the physical limitations found during the clinical examination. The main physical limitation in LE is lack of grip strength due to

R. A. Aguilera Eguía

2009-01-01

152

Genetic steps to organ laterality in zebrafish.  

PubMed

All internal organs are asymmetric along the left-right axis. Here we report a genetic screen to discover mutations which perturb organ laterality. Our particular focus is upon whether, and how, organs are linked to each other as they achieve their laterally asymmetric positions. We generated mutations by ENU mutagenesis and examined F3 progeny using a cocktail of probes that reveal early primordia of heart, gut, liver and pancreas. From the 750 genomes examined, we isolated seven recessive mutations which affect the earliest left-right positioning of one or all of the organs. None of these mutations caused discernable defects elsewhere in the embryo at the stages examined. This is in contrast to those mutations we reported previously (Chen et al., 1997) which, along with left-right abnormalities, cause marked perturbation in gastrulation, body form or midline structures. We find that the mutations can be classified on the basis of whether they perturb relationships among organ laterality. In Class 1 mutations, none of the organs manifest any left-right asymmetry. The heart does not jog to the left and normally leftpredominant BMP4 in the early heart tube remains symmetric. The gut tends to remain midline. There frequently is a remarkable bilateral duplication of liver and pancreas. Embryos with Class 2 mutations have organotypic asymmetry but, in any given embryo, organ positions can be normal, reversed or randomized. Class 3 reveals a hitherto unsuspected gene that selectively affects laterality of heart. We find that visceral organ positions are predicted by the direction of the preceding cardiac jog. We interpret this as suggesting that normally there is linkage between cardiac and visceral organ laterality. Class 1 mutations, we suggest, effectively remove the global laterality signals, with the consequence that organ positions are effectively symmetrical. Embryos with Class 2 mutations do manifest linkage among organs, but it may be reversed, suggesting that the global signals may be present but incorrectly orientated in some of the embryos. That laterality decisions of organs may be independently perturbed, as in the Class 3 mutation, indicates that there are distinctive pathways for reception and organotypic interpretation of the global signals. PMID:18628903

Chen, J N; van Bebber, F; Goldstein, A M; Serluca, F C; Jackson, D; Childs, S; Serbedzija, G; Warren, K S; Mably, J D; Lindahl, P; Mayer, A; Haffter, P; Fishman, M C

2001-01-01

153

Genetic Steps to Organ Laterality in Zebrafish  

PubMed Central

All internal organs are asymmetric along the left–right axis. Here we report a genetic screen to discover mutations which perturb organ laterality. Our particular focus is upon whether, and how, organs are linked to each other as they achieve their laterally asymmetric positions. We generated mutations by ENU mutagenesis and examined F3 progeny using a cocktail of probes that reveal early primordia of heart, gut, liver and pancreas. From the 750 genomes examined, we isolated seven recessive mutations which affect the earliest left–right positioning of one or all of the organs. None of these mutations caused discernable defects elsewhere in the embryo at the stages examined. This is in contrast to those mutations we reported previously (Chen et al., 1997) which, along with left–right abnormalities, cause marked perturbation in gastrulation, body form or midline structures. We find that the mutations can be classified on the basis of whether they perturb relationships among organ laterality. In Class 1 mutations, none of the organs manifest any left–right asymmetry. The heart does not jog to the left and normally leftpredominant BMP4 in the early heart tube remains symmetric. The gut tends to remain midline. There frequently is a remarkable bilateral duplication of liver and pancreas. Embryos with Class 2 mutations have organotypic asymmetry but, in any given embryo, organ positions can be normal, reversed or randomized. Class 3 reveals a hitherto unsuspected gene that selectively affects laterality of heart. We find that visceral organ positions are predicted by the direction of the preceding cardiac jog. We interpret this as suggesting that normally there is linkage between cardiac and visceral organ laterality. Class 1 mutations, we suggest, effectively remove the global laterality signals, with the consequence that organ positions are effectively symmetrical. Embryos with Class 2 mutations do manifest linkage among organs, but it may be reversed, suggesting that the global signals may be present but incorrectly orientated in some of the embryos. That laterality decisions of organs may be independently perturbed, as in the Class 3 mutation, indicates that there are distinctive pathways for reception and organotypic interpretation of the global signals.

Chen, Jau-Nian; van Bebber, Frauke; Goldstein, Allan M.; Serluca, Fabrizio C.; Jackson, Donald; Childs, Sarah; Serbedzija, George; Warren, Kerri S.; Mably, John D.; Lindahl, Per; Mayer, Alan; Haffter, Pascal

2001-01-01

154

Genetics of ALS: Identification of Genes With Roles in Familial and Sporadic Amyotrophic Lateral Sclerosis (ALS) and Amyotrophic Lateral Sclerosis (ALS) With Frontotemporal Dementia  

ClinicalTrials.gov

Amyotrophic Lateral Sclerosis; Familial Amyotrophic Lateral Sclerosis; Amyotrophic Lateral Sclerosis With Frontotemporal Dementia; Lou Gehrig's Disease; Motor Neuron Disease; Primary Lateral Sclerosis

2013-05-03

155

White matter alterations differ in primary lateral sclerosis and amyotrophic lateral sclerosis  

PubMed Central

Primary lateral sclerosis is a sporadic disorder characterized by slowly progressive corticospinal dysfunction. Primary lateral sclerosis differs from amyotrophic lateral sclerosis by its lack of lower motor neuron signs and long survival. Few pathological studies have been carried out on patients with primary lateral sclerosis, and the relationship between primary lateral sclerosis and amyotrophic lateral sclerosis remains uncertain. To detect in vivo structural differences between the two disorders, diffusion tensor imaging of white matter tracts was carried out in 19 patients with primary lateral sclerosis, 18 patients with amyotrophic lateral sclerosis and 19 age-matched controls. Fibre tracking was used to reconstruct the intracranial portion of the corticospinal tract and three regions of the corpus callosum: the genu, splenium and callosal fibres connecting the motor cortices. Both patient groups had reduced fractional anisotropy, a measure associated with axonal organization, and increased mean diffusivity of the reconstructed corticospinal and callosal motor fibres compared with controls, without changes in the genu or splenium. Voxelwise comparison of the whole brain white matter using tract-based spatial statistics confirmed the differences between patients and controls in the diffusion properties of the corticospinal tracts and motor fibres of the callosum. This analysis further revealed differences in the regional distribution of white matter alterations between the patient groups. In patients with amyotrophic lateral sclerosis, the greatest reduction in fractional anisotropy occurred in the distal portions of the intracranial corticospinal tract, consistent with a distal axonal degeneration. In patients with primary lateral sclerosis, the greatest loss of fractional anisotropy and mean diffusivity occurred in the subcortical white matter underlying the motor cortex, with reduced volume, suggesting tissue loss. Clinical measures of upper motor neuron dysfunction correlated with reductions in fractional anisotropy in the corticospinal tract in patients with amyotrophic lateral sclerosis and increased mean diffusivity and volume loss of the corticospinal tract in patients with primary lateral sclerosis. Changes in the diffusion properties of the motor fibres of the corpus callosum were strongly correlated with changes in corticospinal fibres in patients, but not in controls. These findings indicate that degeneration is not selective for corticospinal neurons, but affects callosal neurons within the motor cortex in motor neuron disorders.

Iwata, Nobue K.; Kwan, Justin Y.; Danielian, Laura E.; Butman, John A.; Tovar-Moll, Fernanda; Bayat, Elham

2011-01-01

156

Robust lateral control of highway vehicles  

SciTech Connect

Vehicle lateral dynamics are affected by vehicle mass, longitudinal velocity, vehicle inertia, and the cornering stiffness of the tires. All of these parameters are subject to variation, even over the course of a single trip. Therefore, a practical lateral control system must guarantee stability, and hopefully ride comfort, over a wide range of parameter changes. This paper describes a robust controller which theoretically guarantees stability over a wide range of parameter changes. The robust controller is designed using a frequency domain transfer function approach. An uncertainty band in the frequency domain is determined using simulations over the range of expected parameter variations. Based on this bound, a robust controller is designed by solving the Nevanlinna-Pick interpolation problem. The performance of the robust controller is then evaluated over the range of parameter variations through simulations.

Byrne, R.H. [Sandia National Labs., Albuquerque, NM (United States); Abdallah, C. [New Mexico Univ., Albuquerque, NM (United States). EECE Dept.

1994-08-01

157

The lateral ankle sprain: an experimental study.  

PubMed

An experimental study in 39 ankles of the mechanisms of lateral ankle sprains was carried out using a simple qualitative apparatus. The mechanisms studied were: 1) supination-inversion, which was divided into ankle in plantar flexion and ankle in neutral position, since the orientation and tension of the ankle capsule and ligaments are related to the ankle position; 2) supination-internal rotation; and 3) supination-plantar flexion. Fresh amputation specimens were used. It was concluded that complete rupture of the anterior fibulotalar ligament is always the first lesion to occur in the lateral ankle sprain except when a supination force is applied to the ankle in neutral position when an incomplete tear of the fibulocalcaneal ligament may precede the total rupture of the anterior fibulotalar ligament. A partial rupture of the anterior deep fibers of the deltoid ligament can occur in extreme degrees of internal rotation or plantar flexion. A four-part grading system is suggested. PMID:108406

Dias, L S

1979-04-01

158

Resonant cavity LEDs by lateral epitaxy  

NASA Astrophysics Data System (ADS)

Optical cavity light-emitting diode structures with 'buried' mirrors, and their fabrication by lateral epitaxy are described. Single-crystal, high-quality epitaxial layers are formed over substrates coated with patterned, reflective masks using liquid-phase or vapor-phase epitaxial lateral overgrowth processes. The reflecting mask acts as a backside mirror and forms an optical cavity leading to enhanced external quantum efficiencies. An AlGaAs optical cavity LED incorporating a refractory metal 'buried' mirror is assessed: a greater than 3-fold increase in output optical power is measured compared to control devices with no buried mirror. Application of the epitaxial overgrowth techniques to LED structures utilizing electron-beam deposited dielectric/semiconductor 'buried' mirrors and to other semiconductor materials, such as InGaAsSb, SiC, and ZnSe is described.

Mauk, Michael G.; Burch, P. A.; Johnson, S. W.; Shellenbarger, Zane A.; McNeely, James B.; Goodwin, Thomas A.; Feyock, Bryan W.

1997-04-01

159

Lateral prefrontal cortex contributes to maladaptive decisions  

PubMed Central

Humans consistently make suboptimal decisions involving random events, yet the underlying neural mechanisms remain elusive. Using functional MRI and a matching pennies game that captured subjects’ increasing tendency to predict the break of a streak as it continued [i.e., the “gambler's fallacy” (GF)], we found that a strong blood oxygen level-dependent response in the left lateral prefrontal cortex (LPFC) to the current outcome preceded the use of the GF strategy 10 s later. Furthermore, anodal transcranial direct current stimulation over the left LPFC, which enhances neuronal firing rates and cerebral excitability, increased the use of the GF strategy, and made the decisions more “sticky.” These results reveal a causal role of the LPFC in implementing suboptimal decision strategy guided by false world models, especially when such strategy requires great resources for cognitive control.

Xue, Gui; Juan, Chi-Hung; Chang, Chi-Fu; Lu, Zhong-Lin; Dong, Qi

2012-01-01

160

Traumatic lumbosacral lateral dislocation without fracture  

Microsoft Academic Search

Study design  A unique case of lumbosacral lateral dislocation without fracture is reported.\\u000a \\u000a \\u000a \\u000a Objective  To report on the diagnosis and treatment of a traumatic L5-S1 lateral dislocation in a polytrauma 34-year-old male with L5\\u000a nerve root paralysis.\\u000a \\u000a \\u000a \\u000a Method  Interbody fusion following decompression, posterior reduction and interbody grafting combined with posterior plating was performed.\\u000a \\u000a \\u000a \\u000a Results  At an early stage the patient was able to return

Federico De Iure; Stefania Paderni; Alessandro Gasbarrini; Stefano Bandiera; Stefano Boriani

2008-01-01

161

The management of amyotrophic lateral sclerosis  

Microsoft Academic Search

The terms amyotrophic lateral sclerosis (ALS) or motor neuron disease (MND) refer to a condition characterized by motor system\\u000a degeneration with relative preservation of other pathways. Although there have been advances in symptomatic treatment, ALS\\u000a remains an incurable condition. Advances in ALS management prolong survival but simultaneously raise challenging ethical dilemmas\\u000a for physicians, patients and their families. Here, we review

Julie Phukan; Orla Hardiman

2009-01-01

162

Infant Feeding and Later Obesity Risk  

Microsoft Academic Search

Some 30 years ago, Günter Dörner proposed that exposure to hormones, metabolites and neurotransmitters during limited, sensitive\\u000a periods of early development exert programming effects on disease risk in human adults. Early programming of long term health\\u000a has since received broad scientific support and attention. For example, evidence increases for programming effects of infant\\u000a feeding choices on later obesity risk. Meta-analyses

Berthold Koletzko; R. Kries; R. C. Monasterolo; J. E. Subias; S. Scaglioni; M. Giovannini; J. Beyer; H. Demmelmair; B. Anton; D. Gruszfeld; A. Dobrzanska; A. Sengier; J. P. Langhendries; Marie-Françoise Rolland Cachera; V. Grote

163

Nanodiamond planar lateral field emission diode  

Microsoft Academic Search

We report the fabrication and field emission characteristics of the nanodiamond planar lateral field emission diode. Nanodiamond films with grain size as small as 5–10 nm have been realized through the process of CH4\\/H2\\/N2 microwave plasma enhanced chemical vapor deposition (MPECVD) by employing an effective growth rate reduction technique. Well-controlled processes have been developed; including reactive ion etch (RIE) to

K. Subramanian; W. P. Kang; J. L. Davidson; W. H. Hofmeister; B. K. Choi; M. Howell

2005-01-01

164

Regulation of AMPA receptor lateral movements  

Microsoft Academic Search

An essential feature in the modulation of the efficacy of synaptic transmission is rapid changes in the number of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid) receptors at post-synaptic sites on neurons. Regulation of receptor endo- and exocytosis has been shown to be involved in this process. Whether regulated lateral diffusion of receptors in the plasma membrane also participates in receptor exchange to

Aren J. Borgdorff; Daniel Choquet

2002-01-01

165

Dilational lateral stress in drying latex films.  

PubMed

Drying latex films usually experience tensile stress due to the reduction in volume. While an unconstrained film would shrink affinely in all three dimensions, a coating can only shrink along the vertical and therefore exerts tensile stress onto the substrate. Using an instrument capable of producing maps of the stress distribution, we found that dilational stress sometimes develops as well. The in-plane stress was monitored by spreading the latex dispersion on a flexible membrane. Usually, the membrane bends upward under the tensile stress exerted by the film, but it may also bend downward. Dilational stress was only found with samples showing a strong coffee stain effect, that is, samples in which there is a significant lateral flow from the center to the edge while the film dries. During drying, particles consolidate first at the edge because of the lower height in this region. Continued evaporation from the consolidated region results in a water flow toward the edge, exerting a force onto the latex particles. At the time, when the network is formed, any single sphere must be in a force-balance condition: the network must exert an elastic force onto the sphere which just compensates the viscous drag. Pictorially speaking, a spring (an elastic network) is created while an external force acts onto it. Once the flow stops, the drag force vanishes and the internal stress, which previously compensated the drag, expands the film laterally. This phenomenon can lead to buckling. Given that lateral flow of liquid while films dry is a rather common occurrence, this mode of structure formation should be widespread. It requires lateral flow in conjunction with elastic recovery of the particle network. PMID:20146486

König, Alexander M; Bourgeat-Lami, Elodie; Mellon, Véronique; von der Ehe, Kerstin; Routh, Alexander F; Johannsmann, Diethelm

2010-03-16

166

Lateral Structure of Showers and Energy Flow  

Microsoft Academic Search

\\u000a In this chapter we summarize mainly properties of the lateral structure of all shower particles combined, as recorded by conventional\\u000a surface array detectors. The data that are presented here are a selection from different experiments that are operated at\\u000a atmospheric depths ranging from sea level to the altitude of Mt. Chacaltaya (5,230 m), and from simulations that are representative\\u000a for the

Peter K. F. Grieder

167

Disease progression in amyotrophic lateral sclerosis  

Microsoft Academic Search

This study reports the results of a long-term economic evaluation of riluzole in the treatment of amyotrophic lateral sclerosis\\u000a (ALS) versus best supportive care in the United Kingdom. The analysis included in this contribution aims to provide an update\\u000a of the determination of the phase of the disease that is prolonged by riluzole and also to assess the quality of

Manouche Tavakoli

2002-01-01

168

Frontal lobe dysfunction in amyotrophic lateral sclerosis  

Microsoft Academic Search

The aim of the present study was to investigate the involvement of frontal lobe dysfunction in amyotrophic lateral sclerosis (ALS) using ocular motor paradigms and neuropsychological testing. Fifty-one patients with ALS participated in the following ocular motor tasks: (1) a three-choice task and (2) a remembered saccade task. The patients underwent a clinical and neuropsychological evaluation. One-third of ALS patients

I Evdokimidis; T. S Constantinidis; P Gourtzelidis; N Smyrnis; I Zalonis; P. V Zis; E Andreadou; C Papageorgiou

2002-01-01

169

Lateral–distortional buckling of monorails  

Microsoft Academic Search

This paper is concerned with the elastic lateral–distortional (LD) buckling of single span steel monorail I-beams and its influence on their design strengths. The distortion of a slender web reduces the elastic buckling resistance of an intermediate length beam below its flexural–torsional (FT) resistance. A finite element computer program was used to study the elastic LD buckling of single span

N. S. Trahair

2009-01-01

170

Kainji resettlement housing: 40 years later  

Microsoft Academic Search

Nigeria's Kainji Dam, completed in 1968, displaced 44,000 people from 239 settlements. Three housing forms were designed to provide for urban, semi?urban, and rural settings, respectively. Forty years later, the urban and semi?urban forms are integrated into the community while the rural form, modeled after a grain storage structure (rumbu) has been less successful. Five lessons are derived from this

Ruth Shinenge Gyuse; Timothy Terver Gyuse

2008-01-01

171

The treatment of lateral clavicle fractures  

Microsoft Academic Search

This study assesses the results of surgical treatment of 15 displaced Neer type II fractures of the lateral clavicle in 15 patients, which occurred between November 1988 and March 1995 and which were followed up for a mean period of 4.6 years (range 2–9 years). The patients fell into two groups, one ‘acute group’ and one ‘non-union’ group.Patients treated initially

Mark C. B Webber; John F Haines

2000-01-01

172

Glutamate, excitotoxicity and amyotrophic lateral sclerosis  

Microsoft Academic Search

The “glutamate hypothesis” is one of three major pathophysiological mechanisms of motor neurone injury towards which current\\u000a research effort into amyotrophic lateral sclerosis (ALS) is directed. There is great structural and functional diversity in\\u000a the glutamate receptor family which results from combinations of 14 known gene products and their splice variants, with or\\u000a without additional RNA editing. It is possible

P. J. Shaw; P. G. Ince

1997-01-01

173

Symptomatic torn discoid lateral meniscus in adults  

Microsoft Academic Search

The purposes of this study were to report degenerative changes that coexist with a symptomatic torn discoid lateral meniscus\\u000a in adults and to analyze the factors associated with the accompanied degenerative changes. From 1997 to 2008, 329 knees in\\u000a the 305 patients were included. Associations between the status of the meniscus and the coexisting degenerative changes on\\u000a the images and

Jin Hwan Ahn; Sang-Hee Choi; Yong Seuk Lee; Jae Chul Yoo; Moon Jong Chang; Sooho Bae; Young Ryeol Bae

2011-01-01

174

Outcome after lateral pancreaticojejunostomy for chronic pancreatitis.  

PubMed Central

OBJECTIVE: To assess the outcome of lateral pancreaticojejunostomy in patients with chronic pancreatitis. SUMMARY BACKGROUND DATA: Chronic fibrocalcific pancreatitis associated with pancreatic ductal dilation and chronic pain has been managed successfully with lateral pancreaticojejunostomy. Early results, measured by pain relief and postoperative morbidity and mortality, have been excellent; however, long-term follow-up and overall outcome has been less clearly defined in these patients. METHODS: The outcome of 85 patients who had lateral pancreaticojejunostomy was assessed by reviewing hospital inpatient and outpatient records and conducting patient telephone interviews. RESULTS: Of 62 patients who were alive at follow-up, health status was characterized as good in 24%, fair in 31%, and poor in 45%. Alcohol abuse continued in 42% of patients, whereas narcotic use continued in 35%, insulin use continued in 23%, and pancreatic enzyme supplementation continued in 34%. Rehospitalization for recurrent attacks of pancreatitis and pain was necessary in 40% of patients. Six patients required subsequent operations for complications of chronic pancreatitis. Death occurred in 22 patients (26%) and resulted from continued alcohol abuse, progression of chronic pancreatitis, or late complications of the operation in more than one half the cases. CONCLUSIONS: Although lateral pancreaticojejunostomy provided pain relief, had a low morbidity rate, and no early postoperative deaths, long-term outcome was poor based on the patient's health status, continued alcohol and narcotic use, employment status, subsequent hospitalization to treat recurrent pancreatitis or its complications, subsequent operations required for complications of chronic pancreatitis, and postoperative deaths related to comorbid medical conditions or complications of chronic pancreatitis.

Adams, D B; Ford, M C; Anderson, M C

1994-01-01

175

Palliative care in amyotrophic lateral sclerosis  

Microsoft Academic Search

The poor prognosis of amyotrophic lateral sclerosis (ALS) makes palliative care a challenge for the neurologist. Most disabilities\\u000a associated with progressive disease can be ameliorated by symptomatic treatment. Prognosis and treatment options should be\\u000a openly discussed with the patient and his\\/her relatives. Nutritional deficiency due to pronounced dysphagia can be efficiently\\u000a relieved by a percutaneous enterogastrostomy. Respiratory insufficiency can be

Gian Domenico Borasio; Raymond Voltz

1997-01-01

176

High performance amorphous selenium lateral photodetector  

NASA Astrophysics Data System (ADS)

Lateral amorphous selenium (a-Se) detectors based on the metal-semiconductor-metal (MSM) device structure have been studied for indirect detector medical imaging applications. These detectors have raised interest due to their simple structure, ease of fabrication, high-speed, low dark current, low capacitance per unit area and better light utilization. The lateral device structure has a benefit that the electrode spacing may be easily controlled to reduce the required bias for a given desired electric field. In indirect conversion x-ray imaging, the scintillator is coupled to the top of the a-Se MSM photodetector, which itself is integrated on top of the thin-film-transistor (TFT) array. The carriers generated at the top surface of the a-Se layer experience a field that is parallel to the surface, and does not initially sweep them away from the surface. Therefore these carriers may recombine or get trapped in surface states and change the field at the surface, which may degrade the performance of the photodetector. In addition, due to the finite width of the electrodes, the fill factor of the device is less than unity. In this study we examine the effect of lateral drift of carriers and the fill factor on the photodetector performance. The impact of field magnitude on the performance is also investigated.

Abbaszadeh, Shiva; Allec, Nicholas; Karim, Karim S.

2012-02-01

177

Functional parcellation of the lateral mesencephalus.  

PubMed

The mesencephalic locomotor region (MLR), which includes the pedunculopontine nucleus (PPN) and the cuneiform nucleus (CN), has been recently identified as a key structure for locomotion and gait control in mammals. However, the function and the precise anatomy of the MLR remain unclear in humans. To study the lateral mesencephalus, we used fMRI in 15 right-handed healthy volunteers performing two tasks: imagine walking in a hallway and imagine an object moving along the same hallway. Both tasks were performed at two different speeds: normal and 30% faster. We identified two distinct networks of cortical activation: one involving motor/premotor cortices and the cerebellum for the walking task and the other involving posterior parietal and dorsolateral prefrontal cortices for the object moving task. In the lateral mesencephalus, we found that two different but anatomically connected parts of the MLR were activated during the fast condition of each task. The CN and the dorsal part of the PPN were activated during the fast imaginary walking task, whereas the ventral part of the PPN and the ventral part of the reticular formation were activated while subjects were imagining the object moving fast. Our data suggest that the lateral mesencephalus participates in different aspects of gait in humans, with the CN and dorsal PPN controlling motor aspects of locomotion and the ventral PPN being involved in integrating sensory information. PMID:22764247

Karachi, Carine; André, Arthur; Bertasi, Eric; Bardinet, Eric; Lehéricy, Stéphane; Bernard, Frédéric A

2012-07-01

178

Impaired action knowledge in amyotrophic lateral sclerosis  

PubMed Central

Background: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative condition affecting the motor system, but recent work also shows more widespread cognitive impairment. This study examined performance on measures requiring knowledge of actions, and related performance to MRI cortical atrophy in ALS. Methods: A total of 34 patients with ALS performed measures requiring word-description matching and associativity judgments with actions and objects. Voxel-based morphometry was used to relate these measures to cortical atrophy using high resolution structural MRI. Results: Patients with ALS were significantly more impaired on measures requiring knowledge of actions than measures requiring knowledge of objects. Difficulty on measures requiring action knowledge correlated with cortical atrophy in motor cortex, implicating degraded knowledge of action features represented in motor cortex of patients with ALS. Performance on measures requiring object knowledge did not correlate with motor cortex atrophy. Several areas correlated with difficulty for both actions and objects, implicating these brain areas in components of semantic memory that are not dedicated to a specific category of knowledge. Conclusion: Patients with amyotrophic lateral sclerosis are impaired on measures involving action knowledge, and this appears to be due to at least two sources of impairment: degradation of knowledge about action features represented in motor cortex and impairment on multicategory cognitive components contributing more generally to semantic memory. GLOSSARY ALS = amyotrophic lateral sclerosis; ALSFRS-R = ALS Functional Rating Scale–Revised; FTLD = frontotemporal lobar degeneration; VBM = voxel-based morphometry.

Grossman, M; Anderson, C; Khan, A; Avants, B; Elman, L; McCluskey, L

2008-01-01

179

Lateral dominance in children with learning disabilities.  

PubMed

The purpose of the study was to investigate the occurrence of lateral dominance problems in a sample of children with learning disabilities. Ninety-one children (62 boys, 29 girls) who attended a school for children with learning disabilities were selected for the study. The Harris tests of lateral dominance were administered individually, and the children were rated as having right, left, or mixed dominance for hand, eye, and foot. When compared with normative data on dominance in children, the results showed that the occurrence of mixed hand dominance was no more frequent, the occurrence of mixed eye dominance was less frequent, and the occurrence of mixed foot dominance was more frequent in the children with learning disabilities. Results also showed that the occurrence of mixed and crossed eye-hand dominance was significantly different in children with learning disabilities when compared with children without learning disabilities. However, the occurrence of mixed eye-hand dominance was found to be significantly greater in children without learning disabilities than in learning disabled children. Age and sex were not found to affect the occurrence of lateral dominance problems in children with learning disabilities. PMID:6823468

Connolly, B H

1983-02-01

180

Transnational connections of later-life migrants.  

PubMed

In this paper a transnational perspective is used to explain whether and how older migrants construct and sustain their social networks. The paper uses a transnational viewpoint on older migrants' lives by analysing their engagement with their former homeland, and the intensity and habitualness of those engagements in old age. The aim of this article is to study the transnational connections of later-life migrants'. Attention is especially paid to the features of old age while maintaining these connections. These considerations are based on analyses of transnational networks in the everyday lives of later-life migrants from the former Soviet Union residing in Finland. The data were collected from 11 later-life migrants. It is found that transnational relationships are a vital part of the everyday lives of older migrants, and that they are sustained in varied ways. These connections mean a concrete source of help, family affiliations, the sharing of emotions, and a larger social network. Economic limitations affect the frequency and type of communication, and various physical limitations may also cause inability to maintain contacts across borders. In these circumstances, family members or other close relatives or friends are needed to deliver messages on the older person's behalf. Old age and immigration status affect the amount and direction of communication across borders, thereby shaping these networks. PMID:23561285

Heikkinen, Sari Johanna; Lumme-Sandt, Kirsi

2013-03-29

181

Lateralized auditory symptoms in central neuroaudiology disorder.  

PubMed

Many individuals with central auditory nervous system (CANS) pathology/disorder report a variety of auditory symptoms with difficulty hearing in noise being one of the most common complaints (Chermak and Musiek, 1992) Interestingly, there seems to be a paucity of information in the literature on lateralized hearing loss symptoms in patients with central auditory disorders. Reported here is a case where the patient reported auditory symptoms, specifically hearing loss that was lateralized distinctly to the right ear. This ear was contralateral to a stroke that involved the left hemisphere with neural compromise limited primarily to the left Heschl's gyrus. Although the patient reported other hearing difficulties, the lateralized symptom of right-sided hearing loss seemed to be the most noticed. While the pure-tone audiogram was totally disassociated from the right ear auditory symptoms, central auditory tests revealed a marked and consistent right ear deficit, which was consistent with the site of lesion. It is rare that a relatively small lesion in Heschl's gyrus results in the perception of hearing loss so specifically localized to the right ear. It is also of interest that a patient with definite complaints of hearing loss would yield a normal, highly symmetrical pure-tone audiogram. The triad of patient symptoms, anatomy of the lesion, and central auditory test findings in this case are discussed, and theories as to possible underlying mechanisms for the patient's auditory deficits are provided. PMID:24047943

Musiek, Frank; Guenette, Linda; Fitzgerald, Krista

182

Laterally-biased quantum dot infrared photodetector  

NASA Astrophysics Data System (ADS)

At the Air Force Research Laboratory, Space Vehicles Directorate, we are interested in improving the performance of or modifying the capabilities of infrared detectors in order to locate and identify dim and/or distant objects in space. One characteristic we are very interested in is multicolor detection. To this end, we have turned to a novel detector design that we have come to call a Lateral Quantum Dot Infrared Photodetector (LQDIP). In this design, InAs quantum dots are buried in a GaAs quantum well, which in turn is tunnel-coupled to another GaAs quantum well. Photoexcited electrons from the quantum dots tunnel over to the second well and are then swept out via a lateral (perpendicular to the growth direction) bias voltage. This architecture should exhibit the ability to tune to select infrared frequencies with reduced dark current and unity gain. The lateral photocurrent is directed by a vertical (parallel to the growth direction) gate voltage. We will discuss this detector architecture and the LQDIP operating principles and conditions, and we will present some preliminary results of current-voltage, photocurrent, differential conductance, and spectral measurements.

Cardimona, D. A.; Morath, C. P.; Guidry, D. H.; Cowan, V. M.

2013-07-01

183

Lateral Programmable Metallization Cell Devices And Applications  

NASA Astrophysics Data System (ADS)

Programmable Metallization Cell (PMC) is a technology platform which utilizes mass transport in solid or liquid electrolyte coupled with electrochemical (redox) reactions to form or remove nanoscale metallic electrodeposits on or in the electrolyte. The ability to redistribute metal mass and form metallic nanostructure in or on a structure in situ, via the application of a bias on laterally placed electrodes, creates a large number of promising applications. A novel PMC-based lateral microwave switch was fabricated and characterized for use in microwave systems. It has demonstrated low insertion loss, high isolation, low voltage operation, low power and low energy consumption, and excellent linearity. Due to its non-volatile nature the switch operates with fewer biases and its simple planar geometry makes possible innovative device structures which can be potentially integrated into microwave power distribution circuits. PMC technology is also used to develop lateral dendritic metal electrodes. A lateral metallic dendritic network can be grown in a solid electrolyte (GeSe) or electrodeposited on SiO2 or Si using a water-mediated method. These dendritic electrodes grown in a solid electrolyte (GeSe) can be used to lower resistances for applications like self-healing interconnects despite its relatively low light transparency; while the dendritic electrodes grown using water-mediated method can be potentially integrated into solar cell applications, like replacing conventional Ag screen-printed top electrodes as they not only reduce resistances but also are highly transparent. This research effort also laid a solid foundation for developing dendritic plasmonic structures. A PMC-based lateral dendritic plasmonic structure is a device that has metallic dendritic networks grown electrochemically on SiO2 with a thin layer of surface metal nanoparticles in liquid electrolyte. These structures increase the distribution of particle sizes by connecting pre-deposited Ag nanoparticles into fractal structures and result in three significant effects, resonance red-shift, resonance broadening and resonance enhancement, on surface plasmon resonance for light trapping simultaneously, which can potentially enhance thin film solar cells' performance at longer wavelengths.

Ren, Minghan

184

AVALIAÇÃO DOS RISCOS DE ACIDENTES EM ATIVIDADES DE PODA DE ÁRVORES NA ARBORIZAÇÃO URBANA DO DISTRITO FEDERAL1  

Microsoft Academic Search

RESUMO - Esta pesquisa teve por objetivo avaliar os riscos de acidentes em atividades de poda de árvores na arborização urbana do Distrito Federal. A coleta de dados foi feita com a aplicação de um questionário em forma de entrevista individual. Responderam ao questionário 94% dos funcionários, sendo 92% do total dos operadores de motosserra e 95% do total de

Nilton César Fiedler; Eduardo Hideki Sone; Ailton Teixeira do Vale; José de Fátima Juvêncio; Luciano José Minette

185

Lateral Pharyngotomy for Selected Cancer of the Lateral Oropharynx. Part II: When and Why.  

PubMed

OBJECTIVES/HYPOTHESIS: To analyze local failure following lateral pharyngotomy for selected untreated invasive squamous cell carcinoma (SCC) of the lateral oropharynx. STUDY DESIGN: Retrospective review from a university teaching hospital. METHODS: Inception cohort of 91 patients who underwent lateral pharyngotomy for an isolated and previously untreated selected invasive carcinoma of the lateral oropharynx classified as T1 (26), T2 (47), T3 (11), and T4 (7). Induction chemotherapy, neck dissection, and postoperative radiation therapy were used in 91.2%, 94.5%, and 53.5% of patients. RESULTS: The 5-year Kaplan-Meier estimate of local failure was 16.6% for T1, 19% for T2, 38.6% for T3, and 16.7% for T4 lesions (P?=?.46). In a logistic regression model, only positive margins of resection statistically increased (P?=?.01) the risk for local failure. In patients with safe margins of resection, the 5-year Kaplan-Meier estimate of local failure was 5.6% for T1 lesions, 10.7% for T2 lesions, 23.8% for T3 lesions, and 20% for T4 lesions (P?=?.4). Local failure had a significant impact on increased nodal failure (P?=?.001) and on reduced survival (P?lateral pharyngotomy approach should be viewed as a valuable oncologic alternative to both mandibulotomy and chemoradiation in patients with selected SCC of the lateral oropharynx. LEVEL OF EVIDENCE: 4. Laryngoscope, 2013. PMID:23775844

Laccourreye, Ollivier; Benito, José; Garcia, Dominique; Menard, Madeleine; Bonfils, Pierre; Holsinger, Floyd Christopher

2013-06-18

186

Lateral Interactions in Monolayer Thick Mercury Films  

NASA Astrophysics Data System (ADS)

An understanding of lateral adatom-adatom interactions is often an important part of understanding electronic structure and adsorption energetics in monolayer thick films. In this dissertation I use angle-resolved photoemission and thermal desorption spectroscopies to explore the relationship between the adatom-adatom interaction and other characteristics of the adlayer, such as electronic structure, defects, or coexistent structural phases in the adlayer. Since Hg binds weakly to many substrates, the lateral interactions are often a major contribution to the dynamics of the overlayer. Hg adlayer systems are thus ideal for probing lateral interactions. The electronic structures of Hg adlayers on Ag(100), Cu(100), and Cu_3Au(100) are studied with angle-resolved ultraviolet photoemission. The Hg atomic 5d_{5/2} electronic band is observed to split into two levels following adsorption onto some surfaces. The energetic splitting of the Hg 5d_{5/2} level is found to be directly correlated to the adlayer homogeneous strain energy. The existence of the split off level also depends on the order or disorder of the Hg adlayer. The energetics of Hg adsorption on Cu(100) are probed using thermal desorption spectroscopy. Two different ordered adlayer structures are observed for Hg adsorption on Cu(100) at 200 K. Under some adsorption conditions and over a range of exposures, the two phases are seen to coexist on the surface prior to the thermal desorption process. A phase transition from the more dense to the less dense phase is observed to occur during the thermal desorption process. Inherent differences in defect densities are responsible for the observed differences between lateral interactions measured previously with equilibrium (atom beam scattering) and as measured by the non-equilibrium (thermal desorption) technique reported here. Theoretical and experimental evidence for an indirect through-metal interaction between adatoms is also discussed. Although through-metal interactions may play a role in some adsorption systems, there is little compelling evidence that this effect is significant in many experimental reports where the through metal bond is invoked.

Kime, Yolanda Jan

187

Uniform lateral load capacity of infilled frames  

SciTech Connect

Three tests were conducted on 2.4 meter by 2.4 meter steel frames infilled with structural clay tile to determine the behavior and capacity when subjected to uniform lateral loads. An air bag was used to apply the out-of-plane loads. The walls were subjected to increasing load-unload cycles until virtual destruction of the infill. Cracking in the mortar joints occurred early in the tests, and then the primary load resisting mechanism was arching of the infilled panel. Typically, vertical arching occurred until failure of the top and bottom course tiles. Following failure of these courses, horizontal arching developed enabling the walls to maintain stability.

Flanagan, R.D. [Martin Marietta Energy Systems, Inc., Oak Ridge, TN (United States). Engineering Division; Bennett, R.M. [Tennessee Univ., Knoxville, TN (United States). Dept. of Civil Engineering

1993-11-11

188

Trigemino-abducens synkinesis after lateral orbitotomy.  

PubMed

A 30-year-old man underwent lateral orbitotomy with removal of dermoid cyst in the right orbit. One month after operation, the patient started to experience double vision. He had 25 prism diopters of esotropia in primary gaze with marked limitation of abduction in the right eye. Seven months after the operation, he developed synkinetic movement of the eye when clenching his teeth. He could abduct his right eye while gritting his teeth. This is the fourth reported case of trigemino-abducens synkinesis and the first reported case without brain trauma. PMID:23128534

Park, Kyung-Ah; Oh, Sei Yeul

189

Dynamics of desorption with lateral diffusion  

NASA Astrophysics Data System (ADS)

The dynamics of desorption from a submonolayer of adsorbed atoms or ions are significantly influenced by the absence or presence of lateral diffusion of the adsorbed particles. When diffusion is present, the adsorbate configuration is simultaneously changed by two distinct processes, proceeding in parallel: adsorption/desorption, which changes the total adsorbate coverage, and lateral diffusion, which is coverage conserving. Inspired by experimental results, we here study the effects of these competing processes by kinetic Monte Carlo simulations of a simple lattice-gas model. In order to untangle the various effects, we perform large-scale simulations, in which we monitor coverage, correlation length, and cluster-size distributions, as well as the behavior of representative individual clusters, during desorption. For each initial adsorbate configuration, we perform multiple, independent simulations, without and with diffusion, respectively. We find that, compared to desorption without diffusion, the coverage-conserving diffusion process produces two competing effects: a retardation of the desorption rate, which is associated with a coarsening of the adsorbate configuration, and an acceleration due to desorption of monomers ``evaporated'' from the cluster perimeters. The balance between these two effects is governed by the structure of the adsorbate layer at the beginning of the desorption process. Deceleration and coarsening are predominant for configurations dominated by monomers and small clusters, while acceleration is predominant for configurations dominated by large clusters.

Juwono, Tjipto; Rikvold, Per Arne

2013-09-01

190

The Cortical Signature of Amyotrophic Lateral Sclerosis  

PubMed Central

The aim of this study was to explore the pattern of regional cortical thickness in patients with non-familial amyotrophic lateral sclerosis (ALS) and to investigate whether cortical thinning is associated with disease progression rate. Cortical thickness analysis was performed in 44 ALS patients and 26 healthy controls. Group differences in cortical thickness and the age-by-group effects were assessed using vertex-by-vertex and multivariate linear models. The discriminatory ability of MRI variables in distinguishing patients from controls was estimated using the Concordance Statistics (C-statistic) within logistic regression analyses. Correlations between cortical thickness measures and disease progression rate were tested using the Pearson coefficient. Relative to controls, ALS patients showed a bilateral cortical thinning of the primary motor, prefrontal and ventral frontal cortices, cingulate gyrus, insula, superior and inferior temporal and parietal regions, and medial and lateral occipital areas. There was a significant age-by-group effect in the sensorimotor cortices bilaterally, suggesting a stronger association between age and cortical thinning in ALS patients compared to controls. The mean cortical thickness of the sensorimotor cortices distinguished patients with ALS from controls (C-statistic ?0.74). Cortical thinning of the left sensorimotor cortices was related to a faster clinical progression (r?=??0.33, p?=?0.03). Cortical thickness measurements allowed the detection and quantification of motor and extramotor involvement in patients with ALS. Cortical thinning of the precentral gyrus might offer a marker of upper motor neuron involvement and disease progression.

Agosta, Federica; Valsasina, Paola; Riva, Nilo; Copetti, Massimiliano; Messina, Maria Jose; Prelle, Alessandro; Comi, Giancarlo; Filippi, Massimo

2012-01-01

191

Mirror movements in amyotrophic lateral sclerosis.  

PubMed

Amyotrophic lateral sclerosis (ALS) is a progressive motor syndrome with clinical evidence of upper and lower motor neuron dysfunction. Mirror movements (MM) in ALS have been reported and attributed to a disturbed transcallosal inhibition (TI). Hence, occurrence of MM in ALS might be explained by involvement of transcallosal projecting fibre tracts into the degenerative process of the motor system. Twenty-six consecutive ALS patients were studied by clinical investigation of MM and by transcranial magnetic stimulation testing of TI using evaluation of the ipsilateral silent period. MM were observed in 39% of ALS patients. There was a significant correlation between the revised Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS-R) and occurrence of MM (correlation coefficient -0.315; p = 0.044). In conclusion, all MM patients had pathological TI at least in one hemisphere, which indicates involvement of transcallosally projecting output neurons in ALS patients, which in turn may be an early feature of the disease process with the potential of a diagnostic biomarker. PMID:21554031

Wittstock, Mathias; Meister, Steffanie; Walter, Uwe; Benecke, Reiner; Wolters, Alexander

2011-05-09

192

LATER predicts saccade latency distributions in reading.  

PubMed

When saccades are evoked by suddenly presented visual stimuli, the stochastic distribution of their reaction times is typically recinormal, in conformity with the LATER model of decision-making, sometimes with an additional sub-population of early responses. In the real world, saccades are more often spontaneous responses to static features of the visual world; nevertheless, the time between the end of one saccade and the start of the next may be regarded as a reaction time to the new image that is presented to the retina. The distribution of these times is qualitatively similar to that of evoked saccades, but typically with a longer median and more of the early responses. Here, we analyse the statistical distributions of fixation times from a large database of spontaneous saccades made while reading and show that the distributions are altered in characteristic ways by particular features of the current fixation: likely familiarity of the currently fixated word, and its proximity to the preceding fixation. These alterations are of the kind predicted by LATER: familiarity appears to influence the mean rate at which the decision signal approaches completion, whereas proximity to the previous fixation, presumably because it provides partial prior information about the upcoming word, appears to increase prior probability. We conclude that spontaneous saccades may be successfully described by the same decision-making model that can be used for evoked ones. PMID:16977449

Carpenter, R H S; McDonald, Scott A

2006-09-15

193

Lateral attenuation of military aircraft flight noise  

NASA Astrophysics Data System (ADS)

The results are presented of measurements on the noise propagated to the side of military aircraft during a series of controlled level flyovers. Data were acquired on attack/fighter aircraft (A-10A, F4D, F-5E, F-15, F-16, and F-18); bomber aircraft (B-52G and FB-111); cargo/tanker aircraft (C-18, C-141, KC-10A, KC-135A, and KC-135R); and special purpose aircraft (C-21 and E-3A). In addition to the normal attenuation provided by wave divergence (spherical spreading) and atmospheric absorption, noise propagated laterally to the ground from aircraft during flight is further reduced by the combination of several other frequency dependent phenomena such as ground, meteorological, forward flight, and engine/airplane installation effects. Airbase/airport noise models typically define this extra lateral attenuation for single event measures such as the Sound Exposure Level as a function of the elevation angle as viewed from a given location on the ground. Based on the results of these data, a new algorithm was developed and incorporated in the Air Force NOISEMAP model.

Speakman, Jerry D.

1989-07-01

194

The motor cortex and amyotrophic lateral sclerosis.  

PubMed

On theoretical grounds, abnormalities of the motor cortex in patients with amyotrophic lateral sclerosis (ALS) could lead to anterograde ("dying-forward") transneuronal degeneration of the anterior horn cells as suggested by Charcot. Conversely, retrograde ("dying-back") degeneration of the corticospinal tracts could affect the motor cortex. Evidence derived from clinical, neuropathological, static, and functional imaging, and physiological studies, favors the occurrence of anterograde degeneration. It is hypothesized that transneuronal degeneration in ALS is an active excitotoxic process in which live but dysfunctional corticomotoneurons, originating in the primary motor cortex, drive the anterior horn cell into metabolic deficit. When this is marked, it will result in more rapid and widespread loss of lower motor neurons. In contrast, slow loss of corticomotoneurons, as occurs in primary lateral sclerosis (PLS), precludes excitotoxic drive and is incompatible with anterograde degeneration. Preservation of slow-conducting non-M1 direct pathways in PLS is not associated with excitotoxicity, and anterior horn cells survive for long periods of time. PMID:11268031

Eisen, A; Weber, M

2001-04-01

195

Prototype cantilevers for quantitative lateral force microscopy  

SciTech Connect

Prototype cantilevers are presented that enable quantitative surface force measurements using contact-mode atomic force microscopy (AFM). The ''hammerhead'' cantilevers facilitate precise optical lever system calibrations for cantilever flexure and torsion, enabling quantifiable adhesion measurements and friction measurements by lateral force microscopy (LFM). Critically, a single hammerhead cantilever of known flexural stiffness and probe length dimension can be used to perform both a system calibration as well as surface force measurements in situ, which greatly increases force measurement precision and accuracy. During LFM calibration mode, a hammerhead cantilever allows an optical lever ''torque sensitivity'' to be generated for the quantification of LFM friction forces. Precise calibrations were performed on two different AFM instruments, in which torque sensitivity values were specified with sub-percent relative uncertainty. To examine the potential for accurate lateral force measurements using the prototype cantilevers, finite element analysis predicted measurement errors of a few percent or less, which could be reduced via refinement of calibration methodology or cantilever design. The cantilevers are compatible with commercial AFM instrumentation and can be used for other AFM techniques such as contact imaging and dynamic mode measurements.

Reitsma, Mark G.; Gates, Richard S.; Friedman, Lawrence H.; Cook, Robert F. [Nanomechanical Properties Group, National Institute of Standards and Technology, Gaithersburg, Maryland 20899 (United States)

2011-09-15

196

Mantle Lateral Variations and Earth Tides  

NASA Astrophysics Data System (ADS)

Earth strain and gravity responses to tides or atmospheric loads, are generally calculated assuming radially stratified earth models, and at hydrostatic equilibrium. However, some local observations show unexplained perturbations on the tidal gravity signal. A possible cause for those perturbations may be the neglect of rheology and density lateral variations as well as the non hydrostaticity of the Earth. We have investigated a non radially symmetrical earth numerical model with the intent to study the earth response to low frequency forcings. This model uses a finite element method (spectral elements) developed on the cubed sphere mesh (Chaljub et al., 2003 ; Ronchi et al., 1996), and has resolved the static gravito-elasticity equations. The non-hydrostaticity has been taken into consideration by a first order perturbation theory. As a first validation of our model, we computed the M2 and M3 tidal earth response for a radially stratified model: the Preliminary Referential Earth Model. We obtained, as expected, PREM Love numbers with a very good accuracy. As a second validation, we calculated the effect of ellipticity of the Earth and compared, for homogeneous model or for PREM, our numerical results with analytical solutions (using Maple computations), or literature solutions. Finally, as first applications, we have investigated the influence of the lateral variations induced by oceanic -continental crust distribution, and the possible influence of a mega-plume on gravity tide. In the future, we also intend to extend our approach to more local studies, for features affected by other forces than Earth tides.

Metivier, L.; Greff-Lefftz, M.; Diament, M.

2003-12-01

197

Strath Terraces, Lateral Planation, and Sediment Supply  

NASA Astrophysics Data System (ADS)

Abandoned fluvially eroded bedrock surfaces (strath terraces) are used ubiquitously as indicators of past river elevation. However, little is known about how, why and over what time period they form. Consequently, dates of strath surfaces, or overlying gravels, can be difficult to interpret without a more mechanistic understanding of strath genesis. We mapped strath terraces in detail in the field along the South Fork Eel River and its tributaries in the California Coast Ranges to illuminate the process(es) of lateral bedrock planation. We document two straths along the South Fork Eel: a high strath terrace with a bedrock surface at 9-12 m above the modern low water line and a low strath terrace with a bedrock elevation 2-5 m above modern low water line. Straths are capped with up to 6 meters of gravel, and are locally as much as 3 times the width of the modern river channel. The South Fork Eel incises interbedded sandstone and mudstone of the Franciscan Complex. Straths are usually, but not always, formed in the weaker mudstone. This is consistent with observations in the active river channel indicating mudstone is readily planed down to the low water line by weathering processes and abrasion, whereas sandstone forms resistant ribs that locally constrict the flow. Our observations suggest at least two primary mechanisms drive the lateral planation essential to preserving straths. First, many strath terraces along the South Fork Eel are exposed at the toe of inactive debris fans that entered the channel from tributaries and graded to the higher strath elevation. In these settings, the river has almost always cut vertically through the strath between the outside edge of the fan and a bedrock wall. We interpret this as evidence that when the debris fan was active and the river occupied the high strath, the river was pinned by the debris fan against a bedrock valley wall. This, in turn, suggests lateral sediment input from fans may be important in driving lateral motion of the river. Second, where there is no significant lateral sediment input, straths appear to form at channel meanders. Observations in the active channel suggest that mudstone bedrock will erode much more readily than bars or fans, which are both comprised almost entirely of resistant sandstone boulders. We hypothesize that deposition of point bars, island bars, and debris fans therefore provides a mechanism to preferentially armor one bank of an active channel, leading to erosion of the other bank where mudstone is present. Importantly, along the South Fork Eel the majority of straths appear to form unidirectionally, that is via one continuous sweep of the channel across the strath. Recent dating of strath terraces along the South Fork Eel by others (and additional samples awaiting dating) will be used to evaluate this hypothesis. We assess recent proposals that strath terrace formation on the South Fork Eel is associated with a doubling of hillslope erosion by running HEC- RAS on a LiDAR DEM of the South Fork Eel to model bed sediment transport and bed evolution under different sediment supply scenarios. A primary goal is to explore how up to 6 m of aggradation could be associated with strath terrace formation.

Finnegan, N. J.; Dietrich, W. E.

2008-12-01

198

Meniscoplasty for stable osteochondritis dissecans of the lateral femoral condyle combined with a discoid lateral meniscus: a case report  

PubMed Central

Introduction Osteochondritis dissecans of the lateral femoral condyle is relatively rare, and it is reported to often be combined with a discoid lateral meniscus. Given the potential for healing, conservative management is indicated for stable osteochondritis dissecans in patients who are skeletally immature. However, patients with osteochondritis dissecans of the lateral femoral condyle combined with a discoid lateral meniscus often have persistent symptoms despite conservative management. Case presentation We present the case of a seven-year-old Korean girl who had osteochondritis dissecans of the lateral femoral condyle combined with a discoid lateral meniscus, which healed after meniscoplasty for the symptomatic lateral discoid meniscus without surgical intervention for the osteochondritis dissecans. In addition, healing of the osteochondritis dissecans lesion was confirmed by an MRI scan five months after the operation. Conclusions Meniscoplasty can be recommended for symptomatic stable juvenile osteochondritis dissecans of the lateral femoral condyle combined with a discoid lateral meniscus when conservative treatment fails.

2011-01-01

199

Lateral Quantum Dots for Quantum Information Processing  

NASA Astrophysics Data System (ADS)

The possibility of building a computer that takes advantage of the most subtle nature of quantum physics has been driving a lot of research in atomic and solid state physics for some time. It is still not clear what physical system or systems can be used for this purpose. One possibility that has been attracting significant attention from researchers is to use the spin state of an electron confined in a semiconductor quantum dot. The electron spin is magnetic in nature, so it naturally is well isolated from electrical fluctuations that can a loss of quantum coherence. It can also be manipulated electrically, by taking advantage of the exchange interaction. In this work we describe several experiments we have done to study the electron spin properties of lateral quantum dots. We have developed lateral quantum dot devices based on the silicon metal-oxide-semiconductor transistor, and studied the physics of electrons confined in these quantum dots. We measured the electron spin excited state lifetime, which was found to be as long as 30 ms at the lowest magnetic fields that we could measure. We fabricated and characterized a silicon double quantum dot. Using this double quantum dot design, we fabricated devices which combined a silicon double quantum dot with a superconducting microwave resonator. The microwave resonator was found to be sensitive to two-dimensional electrons in the transistor channel, which we measured and characterized. We developed a new method for extracting information from random telegraph signals, which are produced when we observe thermal fluctuations of electrons in quantum dots. The new statistical method, based on the hidden Markov model, allows us to detect spin-dependent effects in such fluctuations even though we are not able to directly observe the electron spin. We use this analysis technique on data from two experiments involving gallium arsenide quantum dots and use it to measure spin-dependent tunneling rates. Our results advance the understanding of electron spin physics in lateral quantum dots, in silicon and in gallium arsenide.

House, Matthew Gregory

200

RNA interference and amyotrophic lateral sclerosis.  

PubMed

Amyotrophic lateral sclerosis (ALS) is a debilitating neuro-degenerative disorder characterized by progressive loss of motor neurons. The etiology and molecular pathogenesis of cell death in most sub-types of the disease are largely unknown. The best documented cause of moto-neuron degeneration is the mutation in the superoxide dismutase-1 (SOD1) gene, which occurs in 10% of the familial forms of ALS. Discovery of RNA interference (RNAi), which plays an important role in the regulation of gene expression, has proven to be a powerful tool to study the pathogenesis and to develop innovative treatment options for hereditary diseases, including familial variants of ALS. This review summarizes current research advances in RNAi in relation to ALS. PMID:21740381

Rizvanov, Albert A; Gulluoglu, Sukru; Yalvaç, Mehmet E; Palotás, András; Islamov, Rustem R

2011-09-01

201

Frontal lobe dysfunction in amyotrophic lateral sclerosis.  

PubMed

The aim of the present study was to investigate the involvement of frontal lobe dysfunction in amyotrophic lateral sclerosis (ALS) using ocular motor paradigms and neuropsychological testing. Fifty-one patients with ALS participated in the following ocular motor tasks: (1) a three-choice task and (2) a remembered saccade task. The patients underwent a clinical and neuropsychological evaluation. One-third of ALS patients presented with signs of frontal dysfunction, as determined by their high distractibility factors (DF) in the three-choice task and their performances in both the Wisconsin and Stroop tests. ALS patients exhibited longer latencies to eye movement than controls in the performance of the remembered saccade task, specifically in performance of both remembered and delayed saccades, but saccade accuracy was not impaired. Finally, performance indices of the ocular motor tasks, in particular the DF, was correlated only with the degree of dysarthria. PMID:11867070

Evdokimidis, I; Constantinidis, T S; Gourtzelidis, P; Smyrnis, N; Zalonis, I; Zis, P V; Andreadou, E; Papageorgiou, C

2002-03-15

202

Genetics of amyotrophic lateral sclerosis: an update  

PubMed Central

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder involving both upper motor neurons (UMN) and lower motor neurons (LMN). Enormous research has been done in the past few decades in unveiling the genetics of ALS, successfully identifying at least fifteen candidate genes associated with familial and sporadic ALS. Numerous studies attempting to define the pathogenesis of ALS have identified several plausible determinants and molecular pathways leading to motor neuron degeneration, which include oxidative stress, glutamate excitotoxicity, apoptosis, abnormal neurofilament function, protein misfolding and subsequent aggregation, impairment of RNA processing, defects in axonal transport, changes in endosomal trafficking, increased inflammation, and mitochondrial dysfunction. This review is to update the recent discoveries in genetics of ALS, which may provide insight information to help us better understanding of the disease neuropathogenesis.

2013-01-01

203

Catalytic antioxidants to treat amyotropic lateral sclerosis  

PubMed Central

Catalytic antioxidants are comprised of specialised classes of organometallic complexes that can catalyse the decomposition of injurious biological oxidants. These complexes have been shown to prevent the formation of several oxidative markers in spinal cord of G93A amyotropic lateral sclerosis mice and markedly extend survival, even when administered at symptom onset; however, it is now clear that some complexes lacking in antioxidant activity are also protective. New proteomics data suggest that these complexes also induce a broad spectrum of endogenous cellular defense mechanisms. The combination of antioxidant and adaptive resistance effects may explain the remarkable potency of these compounds and may also suggest wide applicability for them in a number of neurodegenerative diseases.

Crow, John P

2010-01-01

204

[From gene to disease: amyotrophic lateral sclerosis].  

PubMed

Amyotrophic lateral sclerosis is a progressive neurological disorder. It is characterised by selective motor-neuron degeneration in the cortex, brainstem, and spinal cord. Consequently, patients suffer from muscle weakness and usually die within 3-5 years after diagnosis from respiratory insufficiency. About 5-10% of the patients have a family history of ALS, the remaining are classified as sporadic ALS. There is only limited information about genetic susceptibility factors in sporadic ALS. Some patients with familial ALS have mutations in the gene encoding for copper/zinc superoxide dismutase, a protein involved in scavenging superoxide radicals. This results in a toxic gain of function. Mutations in the gene coding for alsin, ALS2, have been shown to be responsible for an autosomal recessive form of juvenile ALS. PMID:15553356

van Vught, P W J; Veldink, J H; Baas, F; van Muiswinkel, F L; van den Berg, L H

2004-10-23

205

Magnetic Resonance Imaging in Amyotrophic Lateral Sclerosis  

PubMed Central

Amyotrophic lateral sclerosis (ALS) is a rapidly progressing neurodegenerative disorder which is incurable to date. As there are many ongoing studies with therapeutic candidates, it is of major interest to develop biomarkers not only to facilitate early diagnosis but also as a monitoring tool to predict disease progression and to enable correct randomization of patients in clinical trials. Magnetic resonance imaging (MRI) has made substantial progress over the last three decades and is a practical, noninvasive method to gain insights into the pathology of the disease. Disease-specific MRI changes therefore represent potential biomarkers for ALS. In this paper we give an overview of structural and functional MRI alterations in ALS with the focus on task-free resting-state investigations to detect cortical network failures.

Kollewe, Katja; Korner, Sonja; Dengler, Reinhard; Petri, Susanne; Mohammadi, Bahram

2012-01-01

206

Urinary disorders in amyotrophic lateral sclerosis subjects.  

PubMed

Amyotrophic lateral sclerosis (ALS) related disorders are considered to be uncommon. We hypothesize that urinary dysfunction may occur in ALS patients in the context of spasticity of pelvic floor musculature. We recorded data on 54 subjects with ALS. All subjects were evaluated with ALSFRS and M-Ashworth Scale for lower limbs. Bladder scan procedure was performed to asses post void residual (PVR) in all subjects. Forty-one percent of subjects were symptomatic for urinary disorders and 35% of subjects had a PVR > 50 ml. Linear correlation was found between PVR and ALSFRS with a R(2) 0.95 and p = 0.025; a linear correlation was also noted between PVR and lower limbs Ashworth Scale. We conclude that urinary retention is common in ALS. Urological evaluation is indicated in ALS patients with prominent spasticity. PMID:21506896

Lopes de Carvalho, Maria Laura; Motta, Roberta; Battaglia, Mario Alberto; Brichetto, Giampaolo

2011-04-21

207

Amyotrophic lateral sclerosis: update and new developments  

PubMed Central

Amyotrophic lateral sclerosis (ALS) is the most common form of motor neuron disease. It is typically characterized by adult-onset degeneration of the upper and lower motor neurons, and is usually fatal within a few years of onset. A subset of ALS patients has an inherited form of the disease, and a few of the known mutant genes identified in familial cases have also been found in sporadic forms of ALS. Precisely how the diverse ALS-linked gene products dictate the course of the disease, resulting in compromised voluntary muscular ability, is not entirely known. This review addresses the major advances that are being made in our understanding of the molecular mechanisms giving rise to the disease, which may eventually translate into new treatment options.

Pratt, Ashley J; Getzoff, Elizabeth D; Perry, J Jefferson P

2012-01-01

208

Laterality index in functional MRI: methodological issues?  

PubMed Central

In functional magnetic resonance imaging (fMRI), hemispheric dominance is generally indicated by a measure called the laterality index (LI). The assessment of a meaningful LI measure depends on several methodological factors that should be taken into account when interpreting LI values or comparing between subjects. Principally, these include the nature of the quantification of left and right hemispheres contributions, localisation of volumes of interest within each hemisphere, dependency on statistical threshold, thresholding LI values, choice of activation and baseline conditions and reproducibility of LI values. This review discusses such methodological factors and the different approaches that have been suggested to deal with them. Although these factors are common to a range of fMRI domains, they are discussed here in the context of fMRI of the language system.

Seghier, Mohamed L.

2008-01-01

209

Laterality index in functional MRI: methodological issues.  

PubMed

In functional magnetic resonance imaging (fMRI), hemispheric dominance is generally indicated by a measure called the laterality index (LI). The assessment of a meaningful LI measure depends on several methodological factors that should be taken into account when interpreting LI values or comparing between subjects. Principally, these include the nature of the quantification of left and right hemispheres contributions, localisation of volumes of interest within each hemisphere, dependency on statistical threshold, thresholding LI values, choice of activation and baseline conditions and reproducibility of LI values. This review discusses such methodological factors and the different approaches that have been suggested to deal with them. Although these factors are common to a range of fMRI domains, they are discussed here in the context of fMRI of the language system. PMID:18158224

Seghier, Mohamed L

2007-12-26

210

Lateralized Response Timing Deficits in Autism  

PubMed Central

Background Procedural learning is an implicit process in which a behavioral response is refined through repeated performance. Neural systems supporting this cognitive process include specific frontostriatal systems responsible for the preparation and timing of planned motor responses. Evaluating performance on procedural learning tasks can provide unique information about neurodevelopmental disorders in which frontostriatal disturbances have been reported, such as autism. Methods Fifty-two individuals with autism and 54 age-, IQ-, and gender-matched healthy individuals performed an oculomotor serial reaction time task and a sensorimotor control task. Results Whereas the rate of procedural learning and the precision of planned motor responses were unimpaired in autism, a lateralized alteration in the ability to time predictive responses was observed. Rightward saccadic responses were speeded in individuals with autism relative to healthy control subjects. Conclusions Speeded rightward predictive saccades suggest atypical functioning of left hemisphere striatal chronometric systems in autism.

D'Cruz, Anna-Maria; Mosconi, Matthew W.; Steele, Shelly; Rubin, Leah H.; Luna, Beatriz; Minshew, Nancy; Sweeney, John A.

2011-01-01

211

On lateral competition in dynamic neural networks  

SciTech Connect

Artificial neural networks connected homogeneously, which use retinal image processing methods, are considered. We point out that there are probably two different types of lateral inhibition for each neural element by the neighboring ones-due to the negative connection coefficients between elements and due to the decreasing neuron`s response to a too high input signal. The first case characterized by stable dynamics, which is given by the Lyapunov function, while in the second case, stability is absent and two-dimensional dynamic chaos occurs if the time step in the integration of model equations is large enough. The continuous neural medium approximation is used for analytical estimation in both cases. The result is the partition of the parameter space into domains with qualitatively different dynamic modes. Computer simulations confirm the estimates and show that joining two-dimensional chaos with symmetries provided by the initial and boundary conditions may produce patterns which are genuine pieces of art.

Bellyustin, N.S.

1995-02-01

212

Measuring lateral shuffle and side cut performance.  

PubMed

Whitting, JW, de Melker Worms, JLA, Maurer, C, Nigg, SR, and Nigg, BM. Measuring lateral shuffle and side cut performance. J Strength Cond Res 27(11): 3197-3203, 2013-Lateral shuffle and side cut (SSC) movements are defensive basketball movements where movement speed is critical to performance. The purpose of this study was to compare SSC data obtained using timing lights with motion capture system data and to determine the most appropriate method for measuring SSC performance. Shuffle time data were recorded using both timing lights and a motion capture system while 9 male subjects performed 2 different SSC movement sets, with and without controlling for arm movements, which may influence performance times. Shuffle and side cut times and SSC displacements were used to calculate mean shuffle velocity for each trial. The SEs for the motion capture system were estimated for SSC times (±4.2 milliseconds; ?0.24% of mean shuffle time) and velocities (±5.5 mm·s; ?0.24% of mean shuffle velocity), respectively, indicating high levels of precision. Timing light movement time variability was significantly higher during the uncontrolled (SD = 42 milliseconds) when compared with the controlled (SD = 9 milliseconds, p < 0.001) condition, indicating a significant reduction in variability by controlling non-performance-related variability such as arm movement. A significant positive correlation was found between SSC time and SSC displacement (r = 0.42) indicating that performance times were dependent on displacement. Furthermore, the variance in motion-captured SSC velocity was significantly smaller than the variance in velocity determined using timing lights (p < 0.05). We concluded that motion-captured SSC velocity data reduced systematic errors and non-performance-related movement variability and, therefore, was better able to reflect true performance. As true performance variability in human movement provides important information, the presented method for calculating SSC velocity in this study is recommended for assessing SSC performance. PMID:23439340

Whitting, John W; de Melker Worms, Jonathan L A; Maurer, Christian; Nigg, Sandro R; Nigg, Benno M

2013-11-01

213

Breast feeding and later psychosocial adjustment.  

PubMed

The relationship between the duration of breast feeding and psychosocial outcomes measured between the ages of 15 and 18 years was examined in a birth cohort of 999 New Zealand children. During the period from birth to 1 year, information was collected on maternal breast-feeding practices. Between the ages of 15 and 18 years, sample members were assessed using a range of psychosocial measures, including measures of the quality of parent-child relationships, juvenile delinquency, substance abuse and mental health. Children who were breast fed for a longer duration were more likely to report higher levels of parental attachment and tended to perceive their mothers as being more caring and less overprotective towards them compared with bottle-fed children. No association was found between the extent of breast feeding and subsequent rates of juvenile offending, substance use and mental health in later life. Mothers who elected to breast feed were also more likely to be older, better educated, living with a partner, less likely to smoke during pregnancy, and to come from advantaged socio-economic backgrounds characterised by better living standards and a higher family income. Rates of breast feeding were also greater among mothers who gave birth to a first-born child of higher birthweight. After adjustment for these maternal and perinatal factors, the duration of breast feeding remained significantly associated with adolescent perceptions of maternal care, with increasing duration of breast feeding being associated with higher levels of perceived maternal care during childhood. It is concluded that: (a) it is unlikely that breast feeding is associated with reduced risks of psychiatric disorder in later life; (b) breast feeding may lead to closer parent-child relationships; and (c) it is unlikely that the association between breast feeding and cognitive development is mediated by intervening processes relating to improved psychosocial adjustment in breast-fed children. PMID:10214606

Fergusson, D M; Woodward, L J

1999-04-01

214

Housing in early life and later mortality.  

PubMed Central

STUDY OBJECTIVES--The aim was to examine the influence of domestic crowding and household amenities in early life on later mortality from all causes and specifically from stomach cancer, chronic obstructive pulmonary disease, and rheumatic heart disease. DESIGN--This was a retrospective cohort study of people whose houses had been surveyed in 1936 and whose household size was known from the 1939 census. Subjects were followed through the National Health Service Central Register from 1951 to 1989. SETTING--The housing survey had been carried out in the midland town of Chesterfield. SUBJECTS--Subjects comprised 8138 men and women born after 1900. RESULTS--A total of 2929 deaths were observed during the follow up period. All causes mortality in the full cohort was not consistently related to any of the housing variables examined, but among subjects who were still children at the time of the housing survey, death rates were higher in those whose houses were crowded or lacked a hot water tap. No associations could be shown between stomach cancer and domestic crowding or food storage facilities; chronic obstructive pulmonary disease and domestic crowding or use of gas for cooking; or rheumatic heart disease and domestic crowding. There were few deaths from these causes, however, in subjects who were children at the time of housing survey. CONCLUSIONS--The findings suggest that the housing of young adults in Chesterfield during the 1930s had little effect on their later mortality. Further follow up of the cohort is needed before firm conclusions can be drawn about the influence of housing at younger ages.

Coggon, D; Barker, D J; Inskip, H; Wield, G

1993-01-01

215

Cerebral Laterality and Handedness in Aviation: Performance and Selection Implications.  

National Technical Information Service (NTIS)

This paper reviews the general psychology literature related to handedness and cerebral laterality, beginning with a brief discussion of the research methods employed. Aspects of laterality, including vision, audition, tactile perception, spatial ability,...

J. S. Crowley

1989-01-01

216

5. DETAIL OF TOP CHORD CONNECTION SHOWING LATERAL BRACING, MAIN ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. DETAIL OF TOP CHORD CONNECTION SHOWING LATERAL BRACING, MAIN TIES, TOP LATERAL STRUT, AND INTERMEDIATE POST - Smith Bridge, Spanning Nottely River on Dooley Road (County Road 83), Blairsville, Union County, GA

217

Footballer's Lateral Meniscus: Anterior Horn Tears of the Lateral Meniscus with a Stable Knee  

PubMed Central

This paper aimed to identify the characteristics of isolated anterior horn tear of the lateral meniscus in footballers who underwent arthroscopic surgery. We identified 8 patients with stable knee and no ligament injury, who had only isolated anterior horn tear of the lateral meniscus between 2007 and 2009. All 8 patients were footballers, comprising 7 men and 1 woman with mean age of 18.6 years. Arthroscopy revealed multiple longitudinal tears in 2 patients, longitudinal tear in 2 patients, degenerative tear in 3 patients, and flap tear in 1 patient. Two patients were treated by repair, five by partial excision, and one by rasping only. The mean Lysholm score was 65 before surgery and recovered to 89 at the last followup, on average 12 months after surgery. Anterior horn tear of the lateral meniscus in footballers with a stable knee is characterized by pain at the anterolateral aspect of the knee during knee extension, especially when kicking a ball, and pain during weight-bearing knee extension, together with MRI finding of hyperintense signal in the anterior horn of the lateral meniscus. Preoperative diagnosis may be possible based on these findings in footballers.

Hagino, Tetsuo; Ochiai, Satoshi; Sato, Eiichi; Watanabe, Yoshiyuki; Senga, Shinya

2011-01-01

218

Evidence of lateral antebrachial cutaneous nerve entrapment during autopsy  

Microsoft Academic Search

Compression of the lateral cutaneous nerve of the forearm is a rare clinical entrapment syndrome. This report describes the compression of the lateral antebrachial cutaneous nerve at the level of the lateral margin of the biceps brachii tendon identified during autopsy. This is the first cadaveric case report- ed in the literature. The anatomy, the possible areas of entrapment, the

G. Paraskevas; P. Ph. Tsitsopoulos; B. Papaziogas; K. Natsis; P. Kitsoulis

219

Sex Differences in Cerebral Laterality of Language and Visuospatial Processing  

ERIC Educational Resources Information Center

|Sex differences on language and visuospatial tasks are of great interest, with differences in hemispheric laterality hypothesized to exist between males and females. Some functional imaging studies examining sex differences have shown that males are more left lateralized on language tasks and females are more right lateralized on visuospatial…

Clements, A. M.; Rimrodt, S. L.; Abel, J. R.; Blankner, J. G.; Mostofsky, S. H.; Pekar, J. J.; Denckla, M. B.; Cutting, L. E.

2006-01-01

220

Lateral crashing of tri-axially braided composite tubes  

Microsoft Academic Search

The paper presents the research that is devoted to analyzing the lateral crash of triaxial braided composite tubes. An existing unit-cell based material model for axial crushing of tubes is modified to model the response of the tri-axially braided composites under lateral loads. Matrix, fiber-tension and fiber-compression failures have been considered to account for lateral crash. \\

Nageswara R Janapala; Zhanjun Wu; Fu-Kuo Chang; Robert K. Goldberg

221

The torque test as a measure of lateral dominance.  

PubMed

The present study was designed to assess the validity of the Torque Test as a measure of functional lateral dominance in children. One hundred forty-nine children were administered the Torque Test and The Harris Test of Lateral Dominance. A low but statistically significant correlation was found between torque and total lateral dominance. PMID:6663294

Kraemer, D; Canavan, P; Brannigan, G G; Hijikata, S

1983-12-01

222

The Relationship Between Lateral Dominance and Divergent Cognitive Thought.  

ERIC Educational Resources Information Center

|This study was designed to explore the relationship of lateral dominance to divergent cognitive thought. According to the screening results of the Harris Tests of Lateral Dominance, 36 subjects ranging from 9-12 years were divided equally into three groups of left, right, and mixed lateral dominance. In order to measure divergent cognitive…

Williams, Barbara B.

223

Inelastic lateral buckling strength and design of steel arches  

Microsoft Academic Search

Arches resist general loading by a combination of axial compression and bending actions. Under these actions, an arch loaded in-plane may suddenly deflect laterally and twist out of the plane of loading and fail in a lateral buckling mode. This paper investigates the inelastic lateral buckling strength and design of steel arches under general loading using an advanced nonlinear inelastic

Yong-Lin Pi; N. S Trahair

2000-01-01

224

The management of the popliteus hiatus during lateral meniscal transplantation.  

PubMed

Popliteofascicular injury had been proposed as a possible cause of unstable lateral meniscus. Meniscal repair at popliteal hiatus area during lateral meniscal allograft transplantation (MAT) had not been described in literature previously. In this report, a case of unstable lateral meniscus after MAT has been described. Arthroscopic repair for the unstable meniscus at popliteal hiatus resolved the mechanical symptom. PMID:22578893

Yang, Jae-Hyuk; Jeong, Hyeon-Il; Kim, Taik-Sun; Park, Sung-Chul; Yoon, Jung-Ro

2012-05-10

225

Spatially distributed lateral nitrate transport at the catchment scale  

Microsoft Academic Search

In river catchments, nitrogen transformation and storage processes during lateral transport are important in controlling nitrogen loads of surface waters. There is a lack of approaches which capture lateral flows and associated nitrogen transformation in a spatially distributed way. The aim of this paper is to develop a new conceptual nitrogen transport and transformation model which simulates the lateral nitrate

M. Rode; Uwe Franko; F. Hesser

2010-01-01

226

Structural asymmetries in brains of mice selected for strong lateralization  

Microsoft Academic Search

The brains of 18 female mice from two lines selectively bred for lateralization of paw preference were investigated for morphological asymmetries in 5 horizontal sections from mid-dorsoventral planes. Cortical thickness was measured at orbitofrontal, somatosensory and lateral entorhinal regions; volume measures included the hippocampal formation and the striatum. Mice of the strongly lateralized line had stronger asymmetries in 4 of

H P Lipp; R L Collins; W J Nauta

1984-01-01

227

Differential bilingual laterality: mythical monster found in Wales  

Microsoft Academic Search

Paradis (1992) likens studies of bilingual laterality to reported sightings of the Loch Ness Monster, in that although some studies claim differential laterality much conflicting research evidence does not—and like the mythical Scottish monster, what reason have we to suspect that any such phenomenon might exist? This study reexamines differential bilingual laterality using four groups of English–Welsh bilinguals which differ

Judith Evans; Lance Workman; Peter Mayer; Kevin Crowley

2002-01-01

228

Management of chronic lateral instability due to lateral collateral ligament deficiency after total knee arthroplasty: a case report  

Microsoft Academic Search

INTRODUCTION: Lateral instability following total knee arthroplasty (TKA) is a rare condition with limited report of treatment options. The objective of this case presentation is to demonstrate the outcomes of different surgical procedures performed in a single patient with lateral collateral ligament (LCL) deficiency. CASE PRESENTATION: We present a case of chronic lateral instability due to LCL deficiency after primary

Aasis Unnanuntana; James E Murphy; William J Petersilge

2010-01-01

229

Anatomic and radioanatomic study of the lateral genicular arteries: application to prevention of postoperative hemarthrosis after arthroscopic lateral retinacular release  

Microsoft Academic Search

Arthroscopic lateral retinacular release can be complicated by hemarthrosis in 10 to 18% of cases. The vascular structures involved are the lateral vascular pedicles of the knee. This study examines the topography of these pedicles. Anatomic and radioanatomic studies carried out in 50 specimens defined the route of the vascular pedicles at the lateral aspect of the knee. From the

R. Vialle; J. Y. Tanguy; P. Cronier; H. D. Fournier; X. Papon; P. Mercier

1999-01-01

230

Anatomic and radioanatomic study of the lateral genicular arteries: application to prevention of postoperative hemarthrosis after arthroscopic lateral retinacular release  

Microsoft Academic Search

Summary Arthroscopic lateral retinacular release can be complicated by hemarthrosis in 10 to 18% of cases. The vascular structures involved are the lateral vascular pedicles of the knee. This study examines the topography of these pedicles. Anatomic and radioanatomic studies carried out in 50 specimens defined the route of the vascular pedicles at the lateral aspect of the knee. From

R. Viallel; J. Y. Tanguy; P. Cronier; H. D. Fournier; X. Papon; P. Mercier

1999-01-01

231

Laterality patterns of brain functional connectivity: gender effects.  

PubMed

Lateralization of brain connectivity may be essential for normal brain function and may be sexually dimorphic. Here, we study the laterality patterns of short-range (implicated in functional specialization) and long-range (implicated in functional integration) connectivity and the gender effects on these laterality patterns. Parallel computing was used to quantify short- and long-range functional connectivity densities in 913 healthy subjects. Short-range connectivity was rightward lateralized and most asymmetrical in areas around the lateral sulcus, whereas long-range connectivity was rightward lateralized in lateral sulcus and leftward lateralizated in inferior prefrontal cortex and angular gyrus. The posterior inferior occipital cortex was leftward lateralized (short- and long-range connectivity). Males had greater rightward lateralization of brain connectivity in superior temporal (short- and long-range), inferior frontal, and inferior occipital cortices (short-range), whereas females had greater leftward lateralization of long-range connectivity in the inferior frontal cortex. The greater lateralization of the male's brain (rightward and predominantly short-range) may underlie their greater vulnerability to disorders with disrupted brain asymmetries (schizophrenia, autism). PMID:21878483

Tomasi, Dardo; Volkow, Nora D

2011-08-30

232

Lateral deltopectoral flap: a new and extended flap.  

PubMed

Tissues of the pectoral area such as skin and pectoralis major muscle are used in safe and extended flaps for cervical and neck reconstructions. As blood supply is derived from medial vessels (internal mammary artery) or lateral (thoracodorsal and lateral thoracic arteries), 2 different flaps can be constructed: medial and lateral deltopectoral flaps. Medial deltopectoral flap was developed by Bakamjian as an axial-pattern skin flap, and its blood supply depends on perforating branches from the internal mammary artery. When either parasternal skin or pectoralis major muscle must be resected, this flap obviously cannot be used. In this article, a new lateral deltopectoral flap based on lateral pedicles (from axilla and lateral thoracic area) is described. The successful use of this lateral deltopectoral flap in an extended cervical and thoracic reconstruction after resection of a giant basal cell carcinoma demonstrates that it must be considered as an alternative technique. PMID:19387360

Güerrissi, Jorge Orlando

2009-05-01

233

A pathway for lateral root formation in Arabidopsis thaliana.  

PubMed

In plants, the hormone indole-3-acetic acid (IAA) can initiate the developmental program for lateral root formation. We have isolated mutants that have permitted the dissection of this program into initiation and maturation of lateral roots. The alf1-1 mutation causes hyperproliferation of lateral roots, alf4-1 prevents initiation of lateral roots, and alf3-1 is defective in the maturation of lateral roots. The alf3-1 mutant can be rescued by IAA, whereas the alf4-1 mutant is not rescued. Our data suggest a model in which IAA is required for at least two steps in lateral root development: (1) to initiate cell division in the pericycle, and (2) to promote cell division and maintain cell viability in the developing lateral root. PMID:7657165

Celenza, J L; Grisafi, P L; Fink, G R

1995-09-01

234

COMO IMPLANTAR UM PROGRAMA DE ATIVIDADE FÍSICA NA EMPRESA: SUGESTÃO SEM IMPOSIÇÃO  

Microsoft Academic Search

This work deals with the practice of sport in the company, an expedient that has existed for a long time in European and Asian countries, later adopted in the United States, and arriving in Brazil in the second half of the past century, particularly in the South West and Southern regions - São Paulo, Paraná and Rio Grande do

José Maurício Capinussú

2005-01-01

235

CSF markers in amyotrophic lateral sclerosis.  

PubMed

Amyotrophic lateral sclerosis (ALS, 'Lou Gehrig disease') is the most common, progressive, neurodegenerative, motor neuron disease, causing damage to upper and lower motor neurons, leading to paralysis and death within 3-5 years. Majority of ALS cases are sporadic ALS (SALS) and only 5-10 % of cases are familial ALS (FALS). Pathogenesis of ALS is complicated and still unclear, including genetic, glutamate excitotoxicity, oxidative stress, mitochondrial dysfunction, neurofilament accumulation, impaired trophic support, altered glial function, viral infection, immune imbalance and impairment of the blood-brain, blood-spinal cord and blood-cerebrospinal fluid barriers (BBB/BSCB/BCSFB). The CSF analysis is still one of the basic laboratory tools and might reflect pathophysiological alterations in the course of the disease and could provide an insight into disease pathomechanisms. The most important aim of its analysis is evaluation of blood-CSF barrier, which is altered in 46 % of ALS patients. The CSF biomarkers may give insight into ALS pathophysiology and may be useful for early, presymptomatic diagnosis, therapeutic monitoring and the development of new therapeutic strategies. This review summarizes the general concepts of biomarkers in CSF of ALS patients and their potential usefulness in further research. PMID:22555610

Tarasiuk, Joanna; Ku?akowska, Alina; Drozdowski, Wies?aw; Kornhuber, Johannes; Lewczuk, Piotr

2012-05-04

236

Later first marriage and marital success.  

PubMed

The research reported here used measures of marital success based on both marital survival and marital quality to assess how well first marriages entered at relatively late ages fare in comparison with those entered younger. Analysis of data from five American data sets indicated that the later marriages fare very well in survival but rather poorly in quality. The greatest indicated likelihood of being in an intact marriage of the highest quality is among those who married at ages 22-25, net of the estimated effects of time since first marriage and several variables that might commonly affect age at marriage and marital outcomes. The negative relationship beyond the early to mid-twenties between age at marriage and marital success is likely to be at least partially spurious, and thus it would be premature to conclude that the optimal time for first marriage for most persons is ages 22-25. However, the findings do suggest that most persons have little or nothing to gain in the way of marital success by deliberately postponing marriage beyond the mid-twenties. PMID:22948068

Glenn, Norval D; Uecker, Jeremy E; Love, Robert W B

2010-06-10

237

Amyotrophic lateral sclerosis: A proposed mechanism  

PubMed Central

Missense mutations in Cu,Zn-superoxide dismutase (SOD1) account for ?20% of familial amyotrophic lateral sclerosis (FALS) through some, as yet undefined, toxic gain of function that leads to gradual death of motor neurons. Mitochondrial swelling and vacuolization are early signs of incipient motor neuron death in FALS. We previously reported that SOD1 exists in the intermembrane space of mitochondria. Herein, we demonstrate that the entry of SOD1 into mitochondria depends on demetallation and that heat shock proteins (Hsp70, Hsp27, or Hsp25) block the uptake of the FALS-associated mutant SOD1 (G37R, G41D, or G93A), while having no effect on wild-type SOD1. The binding of mutant SOD1 to Hsps in the extract of neuroblastoma cells leads to formation of sedimentable aggregates. Many antiapoptotic effects of Hsps have been reported. We now propose that this binding of Hsps to mutant forms of a protein abundant in motor neurons, such as SOD1, makes Hsps unavailable for their antiapoptotic functions and leads ultimately to motor neuron death. It also appears that the Hsp–SOD1 complex recruits other proteins present in the neuroblastoma cell and presumably in motor neurons to form sedimentable aggregates.

Okado-Matsumoto, Ayako; Fridovich, Irwin

2002-01-01

238

Amyotrophic lateral sclerosis: a proposed mechanism.  

PubMed

Missense mutations in Cu,Zn-superoxide dismutase (SOD1) account for approximately 20% of familial amyotrophic lateral sclerosis (FALS) through some, as yet undefined, toxic gain of function that leads to gradual death of motor neurons. Mitochondrial swelling and vacuolization are early signs of incipient motor neuron death in FALS. We previously reported that SOD1 exists in the intermembrane space of mitochondria. Herein, we demonstrate that the entry of SOD1 into mitochondria depends on demetallation and that heat shock proteins (Hsp70, Hsp27, or Hsp25) block the uptake of the FALS-associated mutant SOD1 (G37R, G41D, or G93A), while having no effect on wild-type SOD1. The binding of mutant SOD1 to Hsps in the extract of neuroblastoma cells leads to formation of sedimentable aggregates. Many antiapoptotic effects of Hsps have been reported. We now propose that this binding of Hsps to mutant forms of a protein abundant in motor neurons, such as SOD1, makes Hsps unavailable for their antiapoptotic functions and leads ultimately to motor neuron death. It also appears that the Hsp-SOD1 complex recruits other proteins present in the neuroblastoma cell and presumably in motor neurons to form sedimentable aggregates. PMID:12060716

Okado-Matsumoto, Ayako; Fridovich, Irwin

2002-06-11

239

Misregulated RNA processing in amyotrophic lateral sclerosis.  

PubMed

Amyotrophic lateral sclerosis (ALS) research is undergoing an era of unprecedented discoveries with the identification of new genes as major genetic causes of this disease. These discoveries reinforce the genetic, clinical and pathological overlap between ALS and frontotemporal lobar degeneration (FTLD). Common causes of these diseases include mutations in the RNA/DNA-binding proteins, TDP-43 and FUS/TLS and most recently, hexanucleotide expansions in the C9orf72 gene, discoveries that highlight the overlapping pathogenic mechanisms that trigger ALS and FTLD. TDP-43 and FUS/TLS, both of which participate in several steps of RNA processing, are abnormally aggregated and mislocalized in ALS and FTLD, while the expansion in the C9orf72 pre-mRNA strongly suggests sequestration of one or more RNA binding proteins in pathologic RNA foci. Hence, ALS and FTLD converge in pathogenic pathways disrupting the regulation of RNA processing. This article is part of a Special Issue entitled RNA-Binding Proteins. PMID:22444279

Polymenidou, Magdalini; Lagier-Tourenne, Clotilde; Hutt, Kasey R; Bennett, C Frank; Cleveland, Don W; Yeo, Gene W

2012-03-03

240

Impaired Sacculocollic Reflex in Lateral Medullary Infarction  

PubMed Central

Objective: The aim of this study was to determine saccular dysfunction by measuring cervical vestibular-evoked myogenic potentials (cVEMP) and to correlate abnormality of cVEMP with results of other vestibular function tests in lateral medullary infarction (LMI). Methods: We recorded cVEMP in 21 patients with LMI documented on MRI. cVEMP was induced by a short tone burst and was recorded in contracting sternocleidomastoid muscle while patients turned their heads forcefully to the contralateral side against resistance. Patients also underwent video-oculographic recording of spontaneous, gaze-evoked and head shaking nystagmus (HSN), evaluation of ocular tilt reaction (OTR), measurement of the subjective visual vertical (SVV) tilt, bithermal caloric tests, and audiometry. Results: Nine patients (43%) showed abnormal cVEMP, unilateral in seven and bilateral in two. The cVEMP abnormalities included decreased p13–n23 amplitude in four, delayed p13/n23 responses in five, and both decreased and delayed responses in two. The abnormal cVEMP was ipsilesional in five, contralesional in two, and bilateral in two. The prevalence of OTR/SVV tilt, spontaneous nystagmus, and HSN did not differ between the patients with normal and abnormal cVEMP. Conclusion: cVEMP was abnormal in approximately half of the patients with LMI. The abnormal cVEMP indicates damage to the descending sacculocollic reflex pathway or disruption of commissural modulation between the vestibular nuclei.

Kim, Seonhye; Kim, Hyo-Jung; Kim, Ji Soo

2011-01-01

241

Polyglucosan body disease simulating amyotrophic lateral sclerosis.  

PubMed

We describe two patients with polyglucosan body disease (PBD) with the clinical features of atypical amyotrophic lateral sclerosis (ALS). Patient 1 was demented, and patient 2, of Ashkenazi background, was incontinent of urine. Autopsy of patient 1 revealed diffuse CNS accumulations of polyglucosan bodies (PB) localized primarily in neuronal and astrocytic processes and rarely in neuronal perikarya. PB were present in peripheral nerve and myocardium. Brancher enzyme analysis of nerve and muscle was normal. Patient 2's sural nerve biopsy showed PB. Brancher activity was markedly reduced in nerve but not in leukocytes. Previous reports have shown reduced leukocyte brancher activity in Ashkenazi patients with PBD. Clinically, pathologically, and biochemically, PBD is heterogeneous and may include patients presenting with ALS. Cases in which typical pathologic features of PBD are combined with findings of rare PB in neural perikarya may represent a pathologic variant of PBD. Brancher enzyme activity may be normal or only mildly reduced in leukocytes in Ashkenazi patients with PBD, implying genetic heterogeneity. PMID:8469341

McDonald, T D; Faust, P L; Bruno, C; DiMauro, S; Goldman, J E

1993-04-01

242

Immune system alterations in amyotrophic lateral sclerosis.  

PubMed

Amyotrophic lateral sclerosis is a disease of which the underlying cause and pathogenesis are unknown. Cumulatative data clearly indicates an active participation by the immune system in the disease. An increasingly recognized theory suggests a non-cell autonomous mechanism, meaning that multiple cells working together are necessary for the pathogenesis of the disease. Observed immune system alterations could indicate an active participation in this mechanism. Damaged motor neurons are able to activate microglia, astrocytes and the complement system, which further can influence each other and contribute to neurodegeneration. Infiltrating peripheral immune cells appears to correlate with disease progression, but their significance and composition is unclear. The deleterious effects of this collaborating system of cells appear to outweigh the protective aspects, and revealing this interplay might give more insight into the disease. Markers from the classical complement pathway are elevated where its initiator C1q appears to derive primarily from motor neurons. Activated microglia and astrocytes are found in close proximity to dying motor neurons. Their activation status and proliferation seemingly increases with disease progression. Infiltrating monocytes, macrophages and T cells are associated with these areas, although with mixed reports regarding T cell composition. This literature review will provide evidence supporting the immune system as an important part of ALS disease mechanism and present a hypothesis to direct the way for further studies. PMID:23550891

Hovden, H; Frederiksen, J L; Pedersen, S W

2013-04-01

243

Bloch oscillations in lateral periodic nanostructure arrays  

NASA Astrophysics Data System (ADS)

In a periodic structure of electron potential, under an external electric field E, if an electron can reach the boundary of the Brillouin zone (BZ) without being scattered, it undergoes Bragg reflection, passing back into the BZ on the opposite side. This results in a high frequency oscillation of electrons, i.e., Bloch oscillation (BO). Recently, BO has gained a renewed interest, as a Bloch^ oscillator can be utilized as a frequency-tunable THz source. Work on BO has mainly been carried out in quantum well superlattices. On the other hand, a surface superlattices patterned into a two dimensional electron system has long been proposed as an alternative structure to generate BO. Here, we report our experimental results on the negative differential conductance and Bloch oscillation induced edge magnetoplasma resonance in a series of lateral superlattices. Results from the so-called reversed Bloch oscillations measurements and bolometric measurements will also be presented and discussed. Sandia is a multiprogram laboratory operated by Sandia Corporation, a Lockheed Martin company, for the US Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL85000. The facilities of the NSF-sponsored NNIN node at UNM were used for the fabrication.

Pan, W.; Lyo, S. K.; Reno, J. L.; Simmons, J. A.; Li, D.; Brueck, S. R. J.

2009-03-01

244

Respiratory exercise in amyotrophic lateral sclerosis.  

PubMed

We have evaluated the potential role of respiratory exercise by implementing specific inspiratory muscle training in a selected population of early-affected amyotrophic lateral sclerosis (ALS) patients. We studied 26 patients with ALS with normal respiratory function using two groups of patients in a parallel, control-group, randomized, delayed-start design. Patients in the first group (G1) started the active inspiratory exercise programme at entry and were followed for eight months, while the second group (G2) of patients followed a placebo exercise programme for the first four months and then active exercise for the second four-month period. The primary outcome measure was the ALSFRS. Respiratory tests, neurophysiological measurements, fatigue and quality of life scales were secondary outcomes. Analysis of covariance was used to compare changes between and within groups. Results showed that there was no significant difference between the two patient groups. Within-group analysis suggested that inspiratory exercise promotes a transient improvement in the respiratory subscore and in the maximal voluntary ventilation, peak expiratory flow, and sniff inspiratory pressure. In conclusion, there was no clear positive or negative outcome of the respiratory exercise protocol we have proposed, but we cannot rule out a minor positive effect. Exercise regimes merit more detailed clinical evaluation in ALS. PMID:22214352

Pinto, Susana; Swash, Michael; de Carvalho, Mamede

2012-01-01

245

Primary lateral sclerosis: predicting functional outcome.  

PubMed

Our objective was to investigate functional outcome in primary lateral sclerosis (PLS). We followed a group of 24 patients with PLS. Clinical (ALSFRS), respiratory, and neurophysiological (electromyography and transcranial magnetic stimulation) evaluations were performed at entry and regularly over the follow-up period. The time taken for a greater than 10% decrease in ALSFRS compared to the first assessment was defined as the dichotomous outcome; prognostic factors were evaluated using the Cox proportional hazard model. Results demonstrated that the median age at symptom onset was 54 years (range 28-75 years). In 46% symptoms began in the lower limbs, in 21% in the upper limbs and in 33% in bulbar muscles. The median symptom duration at first visit was 3.1 years (range 0.9-11.7 years). At last follow-up the median disease duration was 9.9 years (range 4.2-17.6 years). The median follow-up time was 4.6 years (range 2.1-11 years). We excluded from final analysis three patients with positive family history. Older age at onset (p?=?0.019) was related to more rapid functional impairment; gender, forced vital capacity, region of onset and neurophysiological changes did not predict outcome. In conclusion, age is the most critical prognostic factor for functional outcome in PLS. PMID:22957717

Almeida, Vânia; de Carvalho, Mamede; Scotto, Manuel; Pinto, Susana; Pinto, Anabela; Ohana, Benjamim; Swash, Michael

2012-09-08

246

LATER FIRST MARRIAGE AND MARITAL SUCCESS  

PubMed Central

The research reported here used measures of marital success based on both marital survival and marital quality to assess how well first marriages entered at relatively late ages fare in comparison with those entered younger. Analysis of data from five American data sets indicated that the later marriages fare very well in survival but rather poorly in quality. The greatest indicated likelihood of being in an intact marriage of the highest quality is among those who married at ages 22-25, net of the estimated effects of time since first marriage and several variables that might commonly affect age at marriage and marital outcomes. The negative relationship beyond the early to mid twenties between age at marriage and marital success is likely to be at least partially spurious, and thus it would be premature to conclude that the optimal time for first marriage for most persons is ages 22-25. However, the findings do suggest that most persons have little or nothing to gain in the way of marital success by deliberately postponing marriage beyond the mid twenties.

Glenn, Norval D.; Uecker, Jeremy; Love, Robert W. B.

2012-01-01

247

Altered cortical communication in amyotrophic lateral sclerosis.  

PubMed

Amyotrophic lateral sclerosis (ALS) is a disorder associated primarily with the degeneration of the motor system. More recently, functional connectivity studies have demonstrated potentially adaptive changes in ALS brain organization, but disease-related changes in cortical communication remain unknown. We recruited individuals with ALS and age-matched controls to operate a brain-computer interface while electroencephalography was recorded over three sessions. Using normalized symbolic transfer entropy, we measured directed functional connectivity from frontal to parietal (feedback connectivity) and parietal to frontal (feedforward connectivity) regions. Feedback connectivity was not significantly different between groups, but feedforward connectivity was significantly higher in individuals with ALS. This result was consistent across a broad electroencephalographic spectrum (4-35 Hz), and in theta, alpha and beta frequency bands. Feedback connectivity has been associated with conscious state and was found to be independent of ALS symptom severity in this study, which may have significant implications for the detection of consciousness in individuals with advanced ALS. We suggest that increases in feedforward connectivity represent a compensatory response to the ALS-related loss of input such that sensory stimuli have sufficient strength to cross the threshold necessary for conscious processing in the global neuronal workspace. PMID:23567743

Blain-Moraes, Stefanie; Mashour, George A; Lee, Heonsoo; Huggins, Jane E; Lee, Uncheol

2013-04-06

248

Retinoid signaling alterations in amyotrophic lateral sclerosis  

PubMed Central

Amyotrophic lateral sclerosis (ALS) is a fatal neuromuscular disease for which effective therapeutic interventions and an understanding of underlying disease mechanism are lacking. A variety of biochemical pathways are believed to contribute to the pathophysiology of ALS that are common to both sporadic and familial forms of the disease. Evidence from both human and animal studies indicates that expression of retinoid signaling genes is altered in ALS and may contribute to motor neuron loss. Our goals were to examine the expression and distribution of proteins of the retinoid signaling pathway in spinal cord samples from patients with sporadic and familial ALS and to evaluate the role of these proteins in motor neuron cell survival. In sporadic ALS, the cytoplasmic binding protein that facilitates nuclear translocation of retinoic acid, cellular retinoic acid binding protein-II (CRABP-II), was localized to the nucleus and retinoic acid receptor ? (RAR?) was significantly increased in motor neuron nuclei when compared to either familial ALS patients or non-neurologic disease controls. Motor neurons with increased nuclear RAR? were negative for markers of apoptosis. Pre-treatment of primary motor neuron-enriched cultures with a pan-RAR or RAR?-specific agonist decreased motor neuron cell death associated with oxidative injury/stress while a RAR?-specific antagonist enhanced cell death. Our data suggest retinoid signaling is altered in ALS and increased nuclear RAR? occurs in motor neurons of sporadic ALS patients. Activation of RAR? protects motor neurons from oxidative-induced cell death.

Kolarcik, Christi L; Bowser, Robert

2012-01-01

249

Modeling lateral control in driving studies.  

PubMed

In driving studies based on simulators and instrumented vehicles, specific models are needed to capture key aspects of driving data such as lateral control. We propose a model that uses weighted polynomial projections to predict each data point from the previous three time points, and accommodates the attempts of the drivers to re-center the vehicle before crossing the borders of the traffic lane. Our model also allows the possibility that average position within the lane may vary from driver to driver. We demonstrate how to fit the model using standard statistical procedures available in software packages such as SAS. We used a fixed-base driving simulator to obtain data from 67 drivers with Alzheimer's disease and 128 elderly drivers without dementia. Using these data, we estimated the subject-specific parameters of our model, and we compared the two groups with respect to these parameters. We found that the parameters based on our model were able to distinguish between the groups in an interpretable manner. Hence, this model may be a useful tool to define outcome measures for observational and interventional driving studies. PMID:20380917

Dawson, Jeffrey D; Cavanaugh, Joseph E; Zamba, K D; Rizzo, Matthew

2010-05-01

250

Misregulated RNA processing in amyotrophic lateral sclerosis  

PubMed Central

Amyotrophic lateral sclerosis (ALS) research is undergoing an era of unprecedented discoveries with the identification of new genes as major genetic causes of this disease. These discoveries reinforce the genetic, clinical and pathological overlap between ALS and frontotemporal lobar degeneration (FTLD). Common causes of these diseases include mutations in the RNA/DNA-binding proteins, TDP-43 and FUS/TLS and most recently, hexanucleotide expansions in the C9orf72 gene, discoveries that highlight the overlapping pathogenic mechanisms that trigger ALS and FTLD. TDP-43 and FUS/TLS, both of which participate in several steps of RNA processing, are abnormally aggregated and mislocalized in ALS and FTLD, while the expansion in the C9orf72 pre-mRNA strongly suggests sequestration of one or more RNA binding proteins in pathologic RNA foci. Hence, ALS and FTLD converge in pathogenic pathways disrupting the regulation of RNA processing. This article is part of a Special Issue entitled RNA-Binding Proteins.

Polymenidou, Magdalini; Lagier-Tourenne, Clotilde; Hutt, Kasey R.; Bennett, C. Frank; Cleveland, Don W.; Yeo, Gene W.

2013-01-01

251

Motivation in later life: theory and assessment.  

PubMed

A framework that has been found useful in research on young adults, Deci and Ryan's self-determination theory [1, 2], is suggested as a promising direction for research on motivation in later life. The theory proposes the existence of four types of motivation (intrinsic, self-determined extrinsic, nonself-determined extrinsic, and amotivation) which are assumed to have varying consequences for adaptation and well-being. A previously published French measure of motivational styles which is known to be reliable and valid was translated into English and was tested on seventy-seven nursing home residents (aged 60 to 98 years). It was found that the four motivational styles can be reliably measured; that the intercorrelations between the motivational styles are consistent with theoretical predictions; and that the four types of motivation are related to other important aspects of the lives of elderly people in a theoretically meaningful manner. Suggestions are made for further research using self-determination theory and the present scales. PMID:8666467

Vallerand, R J; O'Connor, B P; Hamel, M

1995-01-01

252

Head Injury and Amyotrophic Lateral Sclerosis  

PubMed Central

Recent data showed that soccer players in Italy had an unusually high risk of amyotrophic lateral sclerosis (ALS) and repeated head trauma might have contributed to this increase. The authors examined whether head injury was related to ALS risk in a case-control study of 109 ALS cases and 255 controls and conducted a meta-analysis of published literature. Overall ever having a head injury was non-significantly associated with a higher ALS risk. When compared with individuals without a head injury, a statistically significant ALS risk elevation was found for participants with more than one head injury (odds ratio (OR): 3.1, 95 percent confidence intervals (CI): 1.2, 8.1) or with head injury during the past 10 years (OR=3.2, 95 percent CI: 1.0, 10.2)). For participants with multiple head injuries in the past 10 years, the risk elevation was more than 11 fold. The meta-analysis also indicated a moderately elevated risk of ALS among individuals with previous head injuries (OR=1.7, 95 percent CI: 1.3, 2.2). In our study population, physical injuries of other body parts, including trunk, arms, or legs, were not related to ALS risk. These data support the notion that head injury may increase the risk of ALS.

Chen, Honglei; Richard, Marie; Sandler, Dale P.; Umbach, David M.; Kamel, Freya

2007-01-01

253

Laterality briefed: laterality modulates performance in a numerosity-congruity task.  

PubMed

It is widely agreed that irrelevant numerical values are automatically activated. However, automatic and intentional activations may give rise to different numerical representations. We examined processing of symbolic and non-symbolic (i.e., numerosity) representations asking whether they differ in automatic and intentional processing. Participants were presented with two-dimensional displays containing repetitions of a digit and were asked to report, in different blocks, whether the digit or numerosity was smaller or larger than 5. Incongruent trials differed either in laterality between the relevant and irrelevant dimensions (i.e., the location of both dimensions in reference to the midpoint 5) or in numerical distance between dimensions. Congruency affected performance regardless of symbolic or non-symbolic presentation. For incongruent trials, laterality (not distance) affected performance, again regardless of presentation. This implies that automaticity does not mean similar processing of relevant and irrelevant dimensions. Specifically, the relevant dimension is processed elaborately whereas the irrelevant dimension is processed crudely. PMID:22227271

Naparstek, Sharon; Henik, Avishai

2012-01-05

254

Does cerebral lateralization develop? A study using functional transcranial Doppler ultrasound assessing lateralization for language production and visuospatial memory  

PubMed Central

In the majority of people, language production is lateralized to the left cerebral hemisphere and visuospatial skills to the right. However, questions remain as to when, how, and why humans arrive at this division of labor. In this study, we assessed cerebral lateralization for language production and for visuospatial memory using functional transcranial Doppler ultrasound in a group of 60 typically developing children between the ages of six and 16 years. The typical pattern of left-lateralized activation for language production and right-lateralized activation for visuospatial memory was found in the majority of the children (58%). No age-related change in direction or strength of lateralization was found for language production. In contrast, the strength of lateralization (independent of direction) for visuospatial memory function continued to increase with age. In addition, boys showed a trend for stronger right-hemisphere lateralization for visuospatial memory than girls, but there was no gender effect on language laterality. We tested whether having language and visuospatial functions in the same hemisphere was associated with poor cognitive performance and found no evidence for this “functional crowding” hypothesis. We did, however, find that children with left-lateralized language production had higher vocabulary and nonword reading age-adjusted standard scores than other children, regardless of the laterality of visuospatial memory. Thus, a link between language function and left-hemisphere lateralization exists, and cannot be explained in terms of maturational change.

Groen, Margriet A; Whitehouse, Andrew J O; Badcock, Nicholas A; Bishop, Dorothy V M

2012-01-01

255

Incidence of Amyotrophic Lateral Sclerosis in Europe  

PubMed Central

Background Geographical differences in amyotrophic lateral sclerosis (ALS) incidence have been reported in the literature, but comparisons across previous studies are limited by different methods in case ascertainment and by the relatively small size of the studied populations. To address these issues, the authors undertook a pooled-analysis of European population-based ALS registries. Methods All new incident ALS cases in subjects 18 years old and older were identified prospectively in six population-based registries in three European countries (Ireland, United Kingdom, Italy) in the two year period 1998-1999 with a reference population of almost 24 million. Results Based on 1,028 identified incident cases, the crude annual incidence rate of ALS in the general European population was 2.16 per 100,000 person-years; 95% CI 2.0-2.3), with similar incidence rates across all registries. The incidence was higher among men (3.0 per 100,000 person-years; 95% CI = 2.8 to 3.3) than among women (2.4 per 100,000 person-years; 95% CI=2.2 to 2.6). Spinal onset ALS was more common among men compared to women, particularly in the 70-80 year age group. Disease occurrence decreases rapidly after 80 years of age. Conclusions ALS incidence is homogeneous across Europe. Sex differences in incidence may be explained by the higher incidence of spinal onset ALS among males and the age-related disease pattern suggests that ALS occurs within a susceptible group within the population rather than being a disease of aging.

Logroscino, Giancarlo; Traynor, Bryan J.; Hardiman, Orla; Chio, Adriano; Mitchell, Douglas; Swingler, Robert J; Millul, Andrea; Benn, Emma; Beghi, Ettore

2010-01-01

256

Lateral Shock of the R Aquarii Jet  

NASA Astrophysics Data System (ADS)

The R Aqr jet was observed with the VLA B-configuration at two epochs separated by ~13.2 yr. Comparison of the resulting 6 cm continuum images show that the radio jet has undergone a lateral counterclockwise rotation of ~6 deg-12 deg on the plane of the sky. The model of jet parcels on independent trajectories is difficult to reconcile with these observations and leads us to consider a path-oriented jet (i.e., younger parcels follow the same path as older parcels). Comparison of the most recent radio image with a nearly contemporaneous HST/FOC ultraviolet image at ~2330 A suggests that the ultraviolet emission lies along the leading side of the rotating radio jet. In conjunction with a proper motion analysis of the jet material that yields empirical space-velocity and resulting acceleration-magnitude relationships as a function of distance from the central source, we evaluate the observational results in terms of a schematic model in which the jet emission consists of plane-parallel isothermal shocks along the leading edge of rotation. In such a radiating shock, the ultraviolet-emitting region is consistent with the adiabatic region in the form of a high-temperature, low-density sheath that surrounds the cooled postshock radio-emitting region. Within the context of the schematic model, we obtain the temperatures, densities, and pressures within the preshock, adiabatic, and postshock regions as a function of distance from the central source; the physical parameters so derived compare favorably to previously published estimates. We obtain a total jet mass of 3.1 x 10-5 M? and an age of ~115 yr. We evaluate the model in the context of its density-boundary condition, its applicability to an episodic or quasi-continuous jet, and angular momentum considerations.

Hollis, J. M.; Pedelty, J. A.; Kafatos, M.

1997-11-01

257

[The symptomatic treatment of amyotrophic lateral sclerosis].  

PubMed

Patients with amyotrophic lateral sclerosis (ALS) have symptoms of progressive muscle weakness, of disturbed speech and swallowing, and in the terminal phase those of respiratory weakness. Treatment options, in particular those for excessive weight loss and respiratory weakness, should be introduced to the patients and their families when the patient is emotionally capable and before dysarthria severely hampers communication. Special equipment for keeping the patient as mobile as possible should be made available much earlier than in the case of other diseases of the muscles as in ALS progression is much faster. Cramps, pathological crying or laughter, spasms, and spasticity can all be treated by medication. When speech can no longer be understood, adaptive strategies such as sign language, mime, posture and communication apparatus varying from a note pad to advanced computer systems can be used. Sialorrhoea, caused by difficulty swallowing with its accompanying danger of aspiration can be halted by the use of medication, by radiotherapy and by the injection into the salivary glands of botulin A toxin. Weight loss, also a result of dysphagia, can be avoided by eating frequent small meals or if necessary performing a percutaneous endoscopic or radiological gastroscopy. Excess mucus in the respiratory tract can be treated with anticholinergics. Difficulty in coughing up thick and sticky mucus cannot always be adequately helped. Respiratory weakness is treatable by external respiratory supportive therapy using a nasal mask, as well as invasive respiratory support via a trachcostoma and by treating the symptoms of respiratory weakness. The latter form of treatment is palliative and forms part of terminal care. During the terminal phase restlessness, anxiety, pain, and dyspnoea require the most attention. Treatment requires careful multidisciplinary cooperation. PMID:15054949

van den Berg, L H; van den Berg, J P; Mathus-Vliegen, E M; Kampelmacher, M J; van Kesteren, R G; Jennekens, F G

2004-03-13

258

Familial Aggregation of Amyotrophic Lateral Sclerosis  

PubMed Central

Objective To assess the relative risk of amyotrophic lateral sclerosis (ALS) in families of ALS patients. Methods We conducted a cohort study based on the Swedish Multi-Generation Register (MGR) in 1961-2005. Among 6,671 probands (first ALS case in the family), 1,909 full siblings, 13,947 children, and 5,405 spouses were identified (exposed group). Other persons in MGR, who were siblings, children, or spouses to persons without ALS, served as the reference group. Relative risks of ALS among the exposed group, compared to the reference group, were calculated from Poisson regression models. Concurrence of ALS within twins was assessed in 86,441 twin pairs registered in the Swedish Twin Register. Results Nine cases of ALS were noted among the siblings and 37 cases among the children of the probands, giving a 17-fold risk among the siblings (95% confidence interval [CI], 8.1-30.4) and a 9-fold risk among the children (95% CI, 6.2-12.0), compared to the reference group. Siblings and children had a higher excess risk if the proband was diagnosed at younger age, and the excess risks decreased with increasing age at diagnosis of the proband (p < 0.001). Spouses had no significantly increased risk (p = 0.27). Two cases were identified among the co-twins of ALS probands, giving a relative risk of 32 (95% CI, 5.2-102.6). Interpretation The siblings and children of ALS patients have an around 10-fold risk of ALS compared to the reference group. The excess risks vary with both age and kinship, indicating a major genetic role in familial ALS.

Kamel, Freya; Lichtenstein, Paul; Bellocco, Rino; Sparen, Par; Sandler, Dale P; Ye, Weimin

2009-01-01

259

Lateral position detection and control for friction stir systems  

DOEpatents

Friction stir methods are disclosed for processing at least one workpiece using a rotary tool with rotating member for contacting and processing the workpiece. The methods include oscillating the rotary tool laterally with respect to a selected propagation path for the rotating member with respect to the workpiece to define an oscillation path for the rotating member. The methods further include obtaining force signals or parameters related to the force experienced by the rotary tool at least while the rotating member is disposed at the extremes of the oscillation. The force signals or parameters associated with the extremes can then be analyzed to determine a lateral position of the selected path with respect to a target path and a lateral offset value can be determined based on the lateral position. The lateral distance between the selected path and the target path can be decreased based on the lateral offset value.

Fleming, Paul (Boulder, CO); Lammlein, David H. (Houston, TX); Cook, George E. (Brentwood, TN); Wilkes, Don Mitchell (Nashville, TN); Strauss, Alvin M. (Nashville, TN); Delapp, David R. (Ashland City, TN); Hartman, Daniel A. (Fairhope, AL)

2011-11-08

260

Differential bilingual laterality: mythical monster found in Wales.  

PubMed

Paradis (1992) likens studies of bilingual laterality to reported sightings of the Loch Ness Monster, in that although some studies claim differential laterality much conflicting research evidence does not-and like the mythical Scottish monster, what reason have we to suspect that any such phenomenon might exist? This study reexamines differential bilingual laterality using four groups of English-Welsh bilinguals which differ in their age of acquisition and in their environment of acquisition. Using a split visual field paradigm we present evidence which, supports the notion of greater right hemisphere processing in a later learned language. Our findings also suggest the pattern of lateralization in bilinguals is strongly affected by the specific language environment during development such that the shift toward greater right hemisphere involvement for the later learned language will be more pronounced in individuals which are brought up in areas where that language is not regularly heard. PMID:12387799

Evans, Judith; Workman, Lance; Mayer, Peter; Crowley, Kevin

2002-11-01

261

Chapter 15 Juvenile amyotrophic lateral sclerosis.  

PubMed

Several forms of genetically defined juvenile amy-otrophic lateral sclerosis (ALS) have now been charac-terized and discussion of these conditions will form the basis for this chapter. ALS2 is an autosomal recessive form of ALS with a juvenile onset and very slow progression that mapped to chromosome 2q33. Nine different mutations have been identified in the ALS2 gene that result in premature stop codons, suggesting a loss of function in the gene product, alsin. The alsin protein is thought to function as a guanine-nucleotide exchange factor for GTPases and may play a role in vesicle transport or membrane trafficking processes. ALS4 is an autosomal dominant form of juvenile onset ALS associated with slow progression, severe muscle weakness and pyramidal signs, in the absence of bulbar and sensory abnormalities. Mutations in the SETX gene cause ALS4, and the SETX gene product senataxin may have DNA and RNA helicase activity and play a role in the regulation of RNA and/or DNA in the cell. A third form of juvenile-onset ALS (ALS5) is associated with slowly progressing lower motor neuron signs (weak-ness and atrophy) initially of the hands and feet, with eventual bulbar involvement. Progressive upper motor neuron disease becomes more obvious with time. ALS5 has been linked to a 6 cM region of chromosome 15q15.1-q21.1, but the causative gene mutation for ALS5 has yet to be identified. The high degree of clin-ical and genetic heterogeneity in the various forms of juvenile ALS can make differential diagnosis difficult, other genetic disorders that must be considered include: spinal muscular atrophy, hereditary spastic paraplegia, SBMA, GM2 gangliosidosis and the hereditary motor neuronopathies/motor forms of Charcot-Marie-Tooth disease. Acquired disorders that must also be consid-ered include heavy metal intoxications (especially lead), multifocal motor neuropathy, paraneoplastic syndromes, vitamin deficiencies (B12) and infections (HTLV-II, HIV and poliomyelitis). PMID:18808900

Orban, Paul; Devon, Rebecca S; Hayden, Michael R; Leavitt, Blair R

2007-01-01

262

Kármán vortex street detection by the lateral line  

Microsoft Academic Search

Fish use the lateral line system for prey detection, predator avoidance, schooling behavior, intraspecific communication and\\u000a spatial orientation. In addition the lateral line may be important for station holding and for the detection of the hydrodynamic\\u000a trails (vortex streets) generated by swimming fish. We investigated the responses of anterior lateral line nerve fibers of\\u000a goldfish, Carassius auratus, to unidirectional water

Boris P. Chagnaud; Horst Bleckmann; Michael H. Hofmann

2007-01-01

263

7. SEGMENT OF LATERAL WITH YUCCA ALONG BANKS, SOUTH OF ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. SEGMENT OF LATERAL WITH YUCCA ALONG BANKS, SOUTH OF 6TH AVENUE (SECTION 10). - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

264

The effect of response mode on lateralized lexical decision performance  

Microsoft Academic Search

We examined the effect of manipulations of response programming, i.e. post-lexical decision making requirements, on lateralized lexical decision. Although response hand manipulations tend to elicit weaker laterality effects than those involving visual field of presentation, the implementation of different lateralized response strategies remains relatively unexplored. Four different response conditions were compared in a between-subjects design: (1) unimanual, (2) bimanual, (3)

Scott A. Weems; Eran Zaidel

2005-01-01

265

4. SEGMENT OF LATERAL WEST OF C STREET (SECTION 10) ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. SEGMENT OF LATERAL WEST OF C STREET (SECTION 10) ON THE ROCKY MOUNTAIN ARSENAL (RMA). - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

266

Analysis of diode lasers with lateral spatial variations in thickness  

SciTech Connect

Diode lasers with active and/or cladding regions whose thicknesses vary spatially parallel to the p-n junction are analyzed. It is shown that lateral real-refractive-index waveguiding occurs and that a diffusion gradient exists which propels the injected charges into the lasing modal volume. Lateral mode patterns and thresholds are calculated and sensitivity to higher-order lateral mode oscillation is evaluated for various stripe widths and spreading resistances. Results are shown to agree well with experimental data.

Streifer, W.; Burnham, R.D.; Scifres, D.R.

1980-07-15

267

Shoreham Railroad Bridge, Former Addison County Railroad (later, Rutland Railroad, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Shoreham Railroad Bridge, Former Addison County Railroad (later, Rutland Railroad, Addison Branch), spanning Lemon Fair River above Richville Pond, west of East Shoreham Road, Shoreham, Addison County, VT

268

Boiler room, west elevation showing gable end and later opening ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Boiler room, west elevation showing gable end and later opening into corridor and wheel bay - Chicago, Burlington & Quincy Railroad, Roundhouse & Shops, Broadway & Spring Streets, Aurora, Kane County, IL

269

23. VIEW SHOWING SALT RIVER PROJECT CREWS SLIPFORMING LATERAL DURING ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

23. VIEW SHOWING SALT RIVER PROJECT CREWS SLIPFORMING LATERAL DURING REHABILITATION AND BETTERMENT PROGRAM Photographer: unknown. April 1968 - Arizona Canal, North of Salt River, Phoenix, Maricopa County, AZ

270

Anterior lateral meniscofemoral ligament with congenital absence of the ACL  

Microsoft Academic Search

Purpose  To describe agenesis of the anterior cruciate ligament (ACL) with an anterior lateral meniscofemoral ligament.\\u000a \\u000a \\u000a \\u000a Methods and results  Case report of a 13-year-old girl with an absent ACL and with an anterior lateral meniscofemoral ligament instead, as well\\u000a as absence of the anterior insertion of the lateral meniscus in the tibia and a discoid ring-like lateral meniscus, with hypoplasia\\u000a of the

Alcindo SilvaRicardo Sampaio; Ricardo Sampaio

2011-01-01

271

Dissociable roles for lateral orbitofrontal cortex and lateral prefrontal cortex during preference driven reversal learning  

PubMed Central

One of the archetypal task manipulations known to depend on frontal-lobe function is reversal learning, where a dominant response must be overridden due to changes in the contingencies relating stimuli, responses, and environmental feedback. Previous studies have indicated that the lateral prefrontal cortex (LPFC), the lateral orbitofrontal cortex (LOFC), the anterior cingulate cortex (ACC), and the caudate nucleus (CN) all contribute to reversal learning. However, the exact contributions that they make during this cognitively complex task remain poorly defined. Here, using functional magnetic resonance imaging, we examine which of the cognitive processes that contribute to the performance of a reversal best predicts the pattern of activation within distinct sub-regions of the frontal lobes. We demonstrate that during reversal learning the LOFC is particularly sensitive to the implementation of the reversal, whereas the LPFC is recruited more generally during attentional control. By contrast, the ACC and CN respond when new searches are initiated regardless of whether the previous response is available, whilst medial orbitofrontal cortex (MOFC) activity is correlated with the positive affect of feedback. These results accord well with the hypothesis that distinct components of adaptable behaviour are supported by anatomically distinct components of the executive system.

Hampshire, Adam; Chaudhry, Amir M.; Owen, Adrian M.; Roberts, Angela C.

2012-01-01

272

Explaining left lateralization for words in the ventral occipitotemporal cortex.  

PubMed

Reading is a uniquely human task and therefore any sign of neuronal activation that is specific to reading is of considerable interest. One intriguing observation is that ventral occipitotemporal (vOT) activation is more strongly left lateralized for written words than other visual stimuli. This has contributed to claims that left vOT plays a special role in reading. Here, we investigated whether left lateralized vOT responses for words were the consequence of visual feature processing, visual word form selectivity, or higher level language processing. Using fMRI in 82 skilled readers, our paradigm compared activation and lateralization for words and nonlinguistic stimuli during different tasks. We found that increased left lateralization for words relative to pictures was the consequence of reduced activation in right vOT rather than increased activation in left vOT. We also found that the determinants of lateralization varied with the subregion of vOT tested. In posterior vOT, lateralization depended on the spatial frequency of the visual inputs. In anterior vOT, lateralization depended on the semantic demands of the task. In middle vOT, lateralization depended on a combination of visual expertise in the right hemisphere and semantics in the left hemisphere. These results have implications for interpreting left lateralized vOT activation during reading. Specifically, left lateralized activation in vOT does not necessarily indicate an increase in left vOT processing but is instead a consequence of decreased right vOT function. Moreover, the determinants of lateralization include both visual and semantic factors depending on the subregion tested. PMID:21994390

Seghier, Mohamed L; Price, Cathy J

2011-10-12

273

Faith, Doubt, and Well-Being in Later Life  

Microsoft Academic Search

This paper examines doubt-within-faith or “quest religiosity” in relation to religious commitment in later life. Although quest religiosity has been labeled by some as religious negativism, we examine the validity of quest as a measure of religious doubt in later life and respond to such criticisms. In addition, we attempt to determine the relationship between religious doubt, measures of religious

James J. Dillon; Andrew Futterman

1998-01-01

274

Isolated lateral pectoral nerve injury: trauma from a seat belt.  

PubMed

A 35-year-old man sustained an isolated injury to the lateral pectoral (anterior thoracic) nerve as the result of a seat belt injury. This resulted in atrophy of the clavicular head of the pectoralis major. Electromyography confirmed localized abnormal findings in this muscle and an isolated lesion of the lateral pectoral nerve, the first reported case of such a lesion. PMID:2923545

Marrero, J L; Goldfine, L J

1989-03-01

275

Mechanical Factors in the Excitation of Clupeid Lateral Lines  

Microsoft Academic Search

The excitation of lateral line sense organs (neuromasts) might be expected to depend on differences of movement between the liquid inside the main lateral line canals (the ones that contain the neuromasts) and the walls of these canals. We have investigated this net movement in relation to events in the water around fish. Liquid displacements inside a given part of

E. J. Denton; John Gray

1983-01-01

276

Neuromagnetic responses to vowels vs. tones reveal hemispheric lateralization  

Microsoft Academic Search

ObjectiveTo evaluate whether a simple auditory paradigm could demonstrate a difference in cortical lateralization between right- and left-handed subjects. Such information would be important for later development of clinical noninvasive tests of hemispheric language dominance in candidates for brain surgery.

E. Kirveskari; R. Salmelin; R. Hari

2006-01-01

277

Lateral Force of a Linear Synchronous Reluctance Motor  

Microsoft Academic Search

The lateral force of a linear synchronous reluctance motor acts as a guidance force when the primary member displaces in a transverse direction. A static test machine, which has a transverse flux coil arrangement and a thin ferromagnetic reaction plate, is manufactured. The lateral force and the thrust are measured in different displacements. Measured result for this segment type reaction

Kokichi Ogawa

278

Measures of Lateral Dominance: Interrelationships and Temporal Stability.  

ERIC Educational Resources Information Center

This study measured test-retest reliabilities and interrelationships of four common measures of lateral dominance: dowel balancing, peg placement, grip strength, and conjugate lateral eye movement. Moderate reliabilities for all measures except grip strength were obtained. Subjects' sex may be an important reliability variable. Correlations among…

Sappington, John T.

1980-01-01

279

Lateral plate asymmetry, diet and parasitism in threespine stickleback  

Microsoft Academic Search

Individuals with random left-right departures from bilateral symmetry are predicted to exhibit fitness reduction including increased parasitism. In an insular lake population of stickleback (Gasterosteus aculeatus) from the Queen Charlotte Islands, Western Canada, phenotypes with high or low number of lateral bony plates exhibited increased plate asymmetry relative to modal phenotypes. Asymmetric lateral plate phenotypes had increased prevalence and to

T. E. R EIMCHEN; P. N OSIL

2001-01-01

280

Handedness, footedness, and language laterality: evidence from Wada testing.  

PubMed

A total of 37 candidates for temporal lobe resection for epilepsy completed the Lateral Dominance Examination, a self-report instrument that measures hand and foot preference. Questionnaire results were compared with speech dominance, which had been determined by Intracarotid Sodium Amytal Procedure. Footedness was as good as handedness as a predictor of language laterality. PMID:15513095

Watson, G S; Pusakulich, R L; Ward, J P; Hermann, B

1998-10-01

281

Measures of Lateral Dominance: Interrelationships and Temporal Stability.  

ERIC Educational Resources Information Center

|This study measured test-retest reliabilities and interrelationships of four common measures of lateral dominance: dowel balancing, peg placement, grip strength, and conjugate lateral eye movement. Moderate reliabilities for all measures except grip strength were obtained. Subjects' sex may be an important reliability variable. Correlations among…

Sappington, John T.

1980-01-01

282

IQ, Fetal Testosterone and Individual Variability in Children's Functional Lateralization  

ERIC Educational Resources Information Center

|Previous event-related potential (ERP) studies have revealed that faces and words show a robust difference in the lateralization of their N170. The present study investigated the development of this differential lateralization in school-age boys. We assessed the potential role of fetal testosterone (FT) level as a factor biasing the prenatal…

Mercure, Evelyne; Ashwin, Emma; Dick, Frederic; Halit, Hanife; Auyeung, Bonnie; Baron-Cohen, Simon; Johnson, Mark H.

2009-01-01

283

Lateral bone density measurements in osteoarthritis of the lumbar spine  

Microsoft Academic Search

OBJECTIVE: To investigate whether spinal osteoarthritis (OA) is responsible for the common finding that lumbar spine bone mineral density (BMD) is greater when measured in the anteroposterior plane than when measured in the lateral plane. METHODS: We studied lateral spine radiographs from 63 women who attended a hospital outpatient department for bone density measurement and who also underwent lumbar spine

D J Peacock; P Egger; P Taylor; M I Cawley; C Cooper

1996-01-01

284

Tidal variability of lateral advection in a coastal plain estuary  

NASA Astrophysics Data System (ADS)

Tidal variability of lateral advection of momentum (vuy, where u and v are along-estuary and lateral flows, respectively, and the subindex indicates differentiation with respect to the cross-estuary direction) was investigated in a coastal plain estuary with observations at Hampton Roads, which is the transition between the James River and Chesapeake Bay. Towed current velocity profiles and hydrographic profiles were captured during 9 expeditions in 2004 and 2005, to determine the intratidal and spatial changes in lateral advection of momentum and its contribution to along-channel flow. Curvature effects and lateral density gradients were important in driving lateral circulation and in modifying intratidal lateral advection of momentum. Lateral advection had the same order of magnitude as the baroclinic pressure gradient. Its contribution to the along-channel momentum balance was greatest during or just after peak flood and weakest at the end of ebb. During peak flood and peak ebb, the spatial distribution of vuy was seaward at the southern (left) side near surface and at the northern side (right) near bed (looking up-estuary), and landward in the rest of the channel. During slack periods the vuy structures were mostly landward. Observations were in good agreement with analytical model results during peak ebb and flood, but inconsistent during slack periods. The discrepancies between model results and field measurements can be attributed to bathymetry-density gradient interactions, which enhanced ebb-to-flood asymmetries in the along-channel and lateral flow.

Basdurak, N. B.; Valle-Levinson, A.

2013-07-01

285

Retreatodontics in maxillary lateral incisor with supernumerary root  

PubMed Central

Familiarity with the intricacies and variations of root canal morphology is essential for successful endodontic treatment. Maxillary central and lateral incisors are known to be single rooted with one canal. This case report describes endodontic retreatment of maxillary lateral incisors with two root canals, one of which was missed during the initial treatment.

Dexton, Antony Johns; Arundas, D; Rameshkumar, M; Shoba, K

2011-01-01

286

Lateral Stability of Ballast - Ballast and Foundation Materials Research Program.  

National Technical Information Service (NTIS)

This report presents the results of the lateral stability study of the Ballast and Foundation Materials Research Program. Full-scale lateral stability tests were conducted with a 2-rail, 3-tie system using slag, crushed limestone, and gravel as ballast. V...

W. W. Hay H. C. Peterson D. E. Plotkin P. T. Bakas

1977-01-01

287

Radial Displacement of Lateral Meniscus After Partial Meniscectomy  

Microsoft Academic Search

Radial displacement or extrusion of the meniscus has been reported as a complication after meniscal transplantation and is sometimes observed in knees with advanced osteoarthritis. In this report, the case of a patient with radial displacement of the lateral meniscus after partial meniscectomy is presented. He had an incomplete discoid lateral meniscus with an anterior horn tear. The inner portion

Nam-Hong Choi

2006-01-01

288

Evidence for Presynaptic Inhibition in the Lateral Geniculate Body  

Microsoft Academic Search

SZENTÀGOTHAI1 reported the presence of axo-axonic endings on fibres entering the lateral geniculate body from the retina. Bizzi and Brooks2 have shown that in the unanaesthetized, unrestrained cat irregular groups of waves could be recorded simultaneously from the pontine reticular formation and the lateral geniculate body during the desynchronized phase of sleep. The latter waves could no longer be recorded

A. Angel; F. Magni; P. Strata

1965-01-01

289

Lateralization of rotational behavior in developing and adult hamsters  

Microsoft Academic Search

Rotational asymmetries were studied in developing and adult hamsters, and compared to verify if early lateralization is a predictor of the animals's later performance. Animals were divided into two groups: group I (GI) was tested from P46 (P1 = day of birth) to P62, group II (GII) was tested daily from P2 to P60. They were placed in a cylindric

Daniela Uziel; M. Cecilia Lopes-Conceição; Ronir R. Luiz; Roberto Lent

1996-01-01

290

A Neural Network Model of Lateralization during Letter Identification  

Microsoft Academic Search

The causes of cerebral lateralization of cognitive and other functions are currently not well understood. To investigate one aspect of function lateralization, a bihemispheric neural network model for a simple visual identification task was developed that has two parallel interacting paths of information processing. The model is based on commonly accepted concepts concerning neural connectivity, activity dynamics, and synaptic plasticity.

Natalia Shevtsova; James A. Reggia

1999-01-01

291

Normal and Lateral Force Calibration Techniques for AFM Cantilevers  

Microsoft Academic Search

Atomic force microscopy (AFM) is a useful tool, not only for imaging but also for quantification of normal and lateral forces exerted on the AFM tip while interacting with the surface of materials. In order to measure these forces, an accurate determination of the normal and lateral forces exerted on the AFM cantilever is necessary. To date, there is no

Manuel L. B. Palacio; Bharat Bhushan

2010-01-01

292

A role for lateral hypothalamic orexin neurons in reward seeking  

Microsoft Academic Search

The lateral hypothalamus is a brain region historically implicated in reward and motivation, but the identity of the neurotransmitters involved are unknown. The orexins (or hypocretins) are neuropeptides recently identified as neurotransmitters in lateral hypothalamus neurons. Although knockout and transgenic overexpression studies have implicated orexin neurons in arousal and sleep, these cells also project to reward-associated brain regions, including the

Glenda C. Harris; Mathieu Wimmer; Gary Aston-Jones

2005-01-01

293

Effect of lateral sphincterotomy on internal anal sphincter function  

Microsoft Academic Search

PURPOSE: This study was designed to investigate the effect of lateral sphincterotomy on internal anal sphincter function in patients with chronic anal fssure. METHODS: Using an eight-channel perfusion catheter and computerized data analysis, a prospective manometric study was performed on patients with chronic anal fissure undergoing lateral sphincterotomy (LS). RESULTS: Mean resting pressure (MRP) in patients with anal fissure (85.1

N. Williams; N. A. Scott; M. H. Irving

1995-01-01

294

LATERAL GENE TRANSFER IN MYCOBACTERIUM AVIUM SUBSPECIES PARATUBERCULOSIS  

Technology Transfer Automated Retrieval System (TEKTRAN)

Lateral gene transfer is an integral part of genome evolution in most bacteria. Bacteria can readily change the contents of their genomes in order to increase adaptability to ever changing surroundings and to generate evolutionary novelty. Here, we report instances of lateral gene transfer in M. avi...

295

High lateral strain ratio in jointed rock masses  

Microsoft Academic Search

Rock masses encountered in the field are jointed and highly anisotropic. An important manifestation of this characteristic of rock masses is that the blocks, when slipping, separate and create voids in the mass resulting in high lateral strain even under low axial stress. It has been shown in this study that the ratio of lateral to axial strain may be

Mahendra Singh; Bhawani Singh

2008-01-01

296

Lateral Epitaxial Overgrowth of Silicon on SiO2.  

National Technical Information Service (NTIS)

The lateral growth of single crystal Si over the edge of a thin (300A) SiO2 bar structure on a single crystal Si substrate using the reduction of SiH4 has been investigated. Lateral-to-vertical growth ratios much greater than 1 have been achieved for appr...

D. D. Rathman D. J. Silversmith J. A. Burns

1982-01-01

297

The relationship between reading ability and lateralized lexical decision  

Microsoft Academic Search

Although lexical decision remains one of the most extensively studied cognitive tasks, very little is known about its relationship to broader linguistic performance such as reading ability. In a correlational study, several aspects of lateralized lexical decision performance were related to vocabulary and reading comprehension measures, as assessed using the Nelson–Denny Reading Test. This lateralized lexical decision task has been

Scott A Weems; Eran Zaidel

2004-01-01

298

Distribution of lateral floor abutment pressure in a stope  

Microsoft Academic Search

In order to study the distribution of lateral floor abutment pressure at a working face, we first used elasticity theory to establish a distribution model of lateral floor abutment pressure and then analysed its distribution. Second, we established a three-dimensional numerical simulation model of the Haizi Coal Mine No. 86 mining area by using FLAC3D (ITASCA Consulting Group) software. We

Zhang Hualei; Wang Lianguo; Sun Jian

2011-01-01

299

Behavior of Laterally Loaded Piles Supporting Bridge Abutments. Phase 1.  

National Technical Information Service (NTIS)

This Final Report describes the work performed in research related to the behavior of laterally loaded piles supporting abutments in which the piles and abutment are built integrally. Pile-abutment systems were built and loaded laterally in a way that sim...

D. W. Goodpasture E. Burdette J. H. Deatherage

2000-01-01

300

The Criminal Histories and Later Offending of Child Pornography Offenders  

Microsoft Academic Search

The likelihood that child pornography offenders will later commit a contact sexual offense is unknown. In the present study, we identified a sample of 201 adult male child pornography offenders using police databases and examined their charges or convictions after the index child pornography offense(s). We also examined their criminal records to identify potential predictors of later offenses: 56% of

Michael C. Seto; Angela W. Eke

2005-01-01

301

Lateralization of magnetic compass orientation in a migratory bird  

Microsoft Academic Search

Lateralization of brain functions, once believed to be a human characteristic, has now been found to be widespread among vertebrates. In birds, asymmetries of visual functions are well studied, with each hemisphere being specialized for different tasks. Here we report lateralized functions of the birds' visual system associated with magnetoperception, resulting in an extreme asymmetry of sensing the direction of

Wolfgang Wiltschko; Joachim Traudt; Onur Güntürkün; Helmut Prior; Roswitha Wiltschko

2002-01-01

302

A lateral active suspension for conventional railway bogies  

Microsoft Academic Search

The present paper describes an active centring system for railway vehicles. The proposed solution is based on lateral pneumatic actuators placed between bogie and car body connected to the vertical secondary suspension air springs. The objective of the developed centring system is twofold: the improvement of the curving behaviour of the train and the decrease of the lateral acceleration perceived

A. Conde Mellado; C. Casanueva; J. Vinolas; J. G. Giménez

2009-01-01

303

Abnormal Brain Lateralization in High-Functioning Autism  

Microsoft Academic Search

Disturbances in lateral preference in autism are of interest because of their potential to shed light on brain maturational processes in this disorder. Forty-seven autistic individuals with a history of disordered early language development and 22 autistic individuals with normal early language acquisition were matched with 112 healthy individuals and compared on a standardized measure of lateral preference, the Edinburgh

Paul R. Escalante-Mead; Nancy J. Minshew; John A. Sweeney

2003-01-01

304

Development of lateral flow membranes for immunoassay separation  

Microsoft Academic Search

The lateral flow nitrocellulose membrane is one of the commonly used separation media for bacteria detection in drinking water treatment facilities. In order to enhance its performance, control of the membrane surface and cross-section morphology is primarily important. The challenge of this study is to combine various formulations and casting variables to obtain lateral flow nitrocellulose membranes with the desired

A. L. Ahmad; S. C. Low; S. R. Abd Shukor; A. Ismail; A. R. Sunarti

2009-01-01

305

LATERAL TURBULENCE INTENSITY AND PLUME MEANDERING DURING STABLE CONDITIONS  

EPA Science Inventory

There is much evidence in the literature for the presence of mesoscale lateral meanders in the stable nighttime boundary layer. These meanders result in relatively high lateral turbulence intensities and diffusion rates when averaged over an hour. Anemometer data from 17 overnigh...

306

Geschwind's Theory of Cerebral Lateralization: Developing a Formal, Causal Model  

Microsoft Academic Search

Geschwind and Galaburda (1987) have proposed a complex and influential model of cerebral lateralization that is based on the argument that increased fetal testosterone levels modify neural development, immune development, and neural crest development. The theory can explain many aspects of cerebral lateralization and its relation to learning disorders, giftedness, and immune deficits. This article clarifies the structure of the

I. C. McManus; M. P. Bryden

1991-01-01

307

Laterality of the Olfactory Event-Related Potential Response  

Microsoft Academic Search

In experimental practice, odors are commonly applied to only one nostril for recordings of olfactory event-related potentials (OERPs), but the lateralization aspect of the OERP response is unclear regarding both stimulated nostril and cortical topography. The purpose of the present study was to investigate whether stimulated-nostril side affects OERP amplitudes and latencies and whether these potentials indicate lateralization of brain

Jonas K. Olofsson; Daniel A. Broman; Paul E. Gilbert; Pamela Dean; Steven Nordin; Claire Murphy

2006-01-01

308

Neuronal plasticity in the cerebellar cortex and lateral nucleus  

Microsoft Academic Search

The cortex and the lateral nucleus of the cerebellum in the normal rat were studied and compared in the electron microscope for examples of changes or apparently spontaneous degeneration in neuronal perikarya and processes. No degenerating neurons and only very rare examples of altered axons were found in the cortex. The lateral nucleus in the same animals, on the other

Victoria Chan-Palay

1973-01-01

309

Phaseolus vulgaris RbohB functions in lateral root development  

PubMed Central

Respiratory burst oxidase homologs (RBOHs) catalyze the reduction of oxygen to generate superoxide anion, a kind of reactive oxygen species (ROS). The ROS produced by RBOHs play essential roles in diverse processes, such as root hair development, stomata closure and signaling mechanisms in response to abiotic stimuli and during plant-pathogen interactions. Recently, we found that PvRbohB silencing in transgenic Phaseolus vulgaris roots had a negative impact on lateral root density. In this work, we show that the downregulation of PvRbohB affects both the growth and ROS levels in recently emerged lateral roots. In addition, we found that the PvRbohB promoter was activated during lateral root primordium initiation in the pericycle, and remained active throughout lateral root development. This study identifies RBOHs as potentially important players in lateral root development in P. vulgaris.

Montiel, Jesus; Arthikala, Manoj-Kumar; Quinto, Carmen

2013-01-01

310

Imaging Findings Associated with Cognitive Performance in Primary Lateral Sclerosis and Amyotrophic Lateral Sclerosis  

PubMed Central

Introduction Executive dysfunction occurs in many patients with amyotrophic lateral sclerosis (ALS), but it has not been well studied in primary lateral sclerosis (PLS). The aims of this study were to (1) compare cognitive function in PLS to that in ALS patients, (2) explore the relationship between performance on specific cognitive tests and diffusion tensor imaging (DTI) metrics of white matter tracts and gray matter volumes, and (3) compare DTI metrics in patients with and without cognitive and behavioral changes. Methods The Delis-Kaplan Executive Function System (D-KEFS), the Mattis Dementia Rating Scale (DRS-2), and other behavior and mood scales were administered to 25 ALS patients and 25 PLS patients. Seventeen of the PLS patients, 13 of the ALS patients, and 17 healthy controls underwent structural magnetic resonance imaging (MRI) and DTI. Atlas-based analysis using MRI Studio software was used to measure fractional anisotropy, and axial and radial diffusivity of selected white matter tracts. Voxel-based morphometry was used to assess gray matter volumes. The relationship between diffusion properties of selected association and commissural white matter and performance on executive function and memory tests was explored using a linear regression model. Results More ALS than PLS patients had abnormal scores on the DRS-2. DRS-2 and D-KEFS scores were related to DTI metrics in several long association tracts and the callosum. Reduced gray matter volumes in motor and perirolandic areas were not associated with cognitive scores. Conclusion The changes in diffusion metrics of white matter long association tracts suggest that the loss of integrity of the networks connecting fronto-temporal areas to parietal and occipital areas contributes to cognitive impairment.

Meoded, Avner; Kwan, Justin Y.; Peters, Tracy L.; Huey, Edward D.; Danielian, Laura E.; Wiggs, Edythe; Morrissette, Arthur; Wu, Tianxia; Russell, James W.; Bayat, Elham; Grafman, Jordan; Floeter, Mary Kay

2013-01-01

311

lmmunocytochemical Studies of the Peptidergic Content of Fibers and Terminals Within the Lateral Spinal and Lateral Cervical Nuclei  

Microsoft Academic Search

As part of a series of studies in which we are attempting to determine the roles of the lateral spinal (LSn) and lateral cervical (LCn) nuclei in somatic sensation, we have examined the fibers and terminals within these nuclei in the rat using the indirect immunofluorescence technique. Eleven antisera were used. Within the LSn, antisera against dynorphin 1-8 (DYN), substance

GLENN J. GIESLER; ROBERT P. ELDE

312

Functional cerebral lateralization and dual-task efficiency—Testing the function of human brain lateralization using fTCD  

Microsoft Academic Search

It has been hypothesized that functional cerebral lateralization enhances cognitive performance. Evidence was found in birds and fish. Our study aimed to test this hypothesis by analyzing the relationship between cerebral lateralization and both single-task performance and dual-task efficiency in humans. We combined a dynamic Landmark task which is assumed to be primarily processed in the right hemisphere and a

J. M. Lust; R. H. Geuze; A. G. G. Groothuis; A. Bouma

2011-01-01

313

Lateral force calibration in atomic force microscopy: A new lateral force calibration method and general guidelines for optimization  

SciTech Connect

Proper force calibration is a critical step in atomic and lateral force microscopies (AFM/LFM). The recently published torsional Sader method [C. P. Green et al., Rev. Sci. Instrum. 75, 1988 (2004)] facilitates the calculation of torsional spring constants of rectangular AFM cantilevers by eliminating the need to obtain information or make assumptions regarding the cantilever's material properties and thickness, both of which are difficult to measure. Complete force calibration of the lateral signal in LFM requires measurement of the lateral signal deflection sensitivity as well. In this article, we introduce a complete lateral force calibration procedure that employs the torsional Sader method and does not require making contact between the tip and any sample. In this method, a colloidal sphere is attached to a 'test' cantilever of the same width, but different length and material as the 'target' cantilever of interest. The lateral signal sensitivity is calibrated by loading the colloidal sphere laterally against a vertical sidewall. The signal sensitivity for the target cantilever is then corrected for the tip length, total signal strength, and in-plane bending of the cantilevers. We discuss the advantages and disadvantages of this approach in comparison with the other established lateral force calibration techniques, and make a direct comparison with the 'wedge' calibration method. The methods agree to within 5%. The propagation of errors is explicitly considered for both methods and the sources of disagreement discussed. Finally, we show that the lateral signal sensitivity is substantially reduced when the laser spot is not centered on the detector.

Cannara, Rachel J.; Eglin, Michael; Carpick, Robert W. [Physics Department, University of Wisconsin-Madison, 1150 University Ave., Madison, Wisconsin 53706 (United States); Engineering Physics Department, University of Wisconsin-Madison, 1500 Engineering Dr., Madison, Wisconsin 53706 (United States)

2006-05-15

314

Childhood laterality and adult schizophrenia spectrum disorders: a prospective investigation.  

PubMed

Left or mixed-handedness, footedness, and eye dominance are thought to indicate abnormalities in lateralization related to schizophrenia. Increased left or mixed-dominance in schizophrenia suggests possible hemispheric abnormalities associated with the disorder. A related body of research suggests that some indications of lateralization abnormalities may be evident prior to the onset of schizophrenia, suggesting that disruptions in lateralization are inherent to the developmental course of the disorder. We attempted to replicate and extend upon findings indicating differences in lateralization between children who later developed a schizophrenia spectrum disorder (n = 26) and those who did not develop a schizophrenia spectrum disorder (n = 216), among a high-risk and control, longitudinal sample. The rate of left or mixed-footedness, eye dominance, and any anomalous lateralization, but not handedness, discriminated between those who developed schizophrenia spectrum disorders and those who did not. Left or mixed-laterality appears to signal neurological disruption relevant to the development of schizophrenia spectrum disorders. PMID:15560960

Schiffman, Jason; Pestle, Sarah; Mednick, Sara; Ekstrom, Morten; Sorensen, Holger; Mednick, Sarnoff

2005-01-01

315

Epigenesis of behavioural lateralization in humans and other animals  

PubMed Central

Despite several decades of research, the epigenesis of behavioural and brain lateralization is still elusive, although its knowledge is important in understanding developmental plasticity, function and evolution of lateralization, and its relationship with developmental disorders. Over the last decades, it has become clear that behavioural lateralization is not restricted to humans, but a fundamental principle in the organization of behaviour in vertebrates. This has opened the possibility of extending descriptive studies on human lateralization with descriptive and experimental studies on other vertebrate species. In this review, we therefore explore the evidence for the role of genes and environment on behavioural lateralization in humans and other animals. First, we discuss the predominant genetic models for human handedness, and conclude that their explanatory power alone is not sufficient, leaving, together with ambiguous results from adoption studies and selection experiments in animals, ample opportunity for a role of environmental factors. Next, we discuss the potential influence of such factors, including perinatal asymmetrical perception induced by asymmetrical head position or parental care, and social modulation, both in humans and other vertebrates, presenting some evidence from our own work on the domestic chick. We conclude that both perinatal asymmetrical perception and later social modulation are likely candidates in influencing the degree or strength of lateralization in both humans and other vertebrates. However, in most cases unequivocal evidence for this is lacking and we will point out further avenues for research.

Schaafsma, S.M.; Riedstra, B.J.; Pfannkuche, K.A.; Bouma, A.; Groothuis, T.G.G.

2008-01-01

316

Selective lumbar neuroforaminal decompression in lateral spinal stenosis  

Microsoft Academic Search

Summary\\u000a Objectives  To eliminate radicular symptoms by decompression of a lumbar nerve root (usually L5) from its dural exit to the intervertebral\\u000a foramen up to the lateral compartment without damaging the facet joint.\\u000a \\u000a \\u000a \\u000a \\u000a Indications  Bony compression of a lumbar nerve root at the lateral recess. in the intervertebral foramen. and in the intervertebral compartment.\\u000a The mediolateral and lateral decompression is indicated in

Arnaldo Benini

2000-01-01

317

The auxin influx carrier LAX3 promotes lateral root emergence.  

PubMed

Lateral roots originate deep within the parental root from a small number of founder cells at the periphery of vascular tissues and must emerge through intervening layers of tissues. We describe how the hormone auxin, which originates from the developing lateral root, acts as a local inductive signal which re-programmes adjacent cells. Auxin induces the expression of a previously uncharacterized auxin influx carrier LAX3 in cortical and epidermal cells directly overlaying new primordia. Increased LAX3 activity reinforces the auxin-dependent induction of a selection of cell-wall-remodelling enzymes, which are likely to promote cell separation in advance of developing lateral root primordia. PMID:18622388

Swarup, Kamal; Benková, Eva; Swarup, Ranjan; Casimiro, Ilda; Péret, Benjamin; Yang, Yaodong; Parry, Geraint; Nielsen, Erik; De Smet, Ive; Vanneste, Steffen; Levesque, Mitch P; Carrier, David; James, Nicholas; Calvo, Vanessa; Ljung, Karin; Kramer, Eric; Roberts, Rebecca; Graham, Neil; Marillonnet, Sylvestre; Patel, Kanu; Jones, Jonathan D G; Taylor, Christopher G; Schachtman, Daniel P; May, Sean; Sandberg, Goran; Benfey, Philip; Friml, Jiri; Kerr, Ian; Beeckman, Tom; Laplaze, Laurent; Bennett, Malcolm J

2008-07-11

318

Electrical design for lateral junction photonic crystal lasers  

NASA Astrophysics Data System (ADS)

We model conduction and free-carrier injection in laterally doped GaAs p-i-n diodes formed in one and twodimensional photonic crystal (PC) nanocavities. Finite element simulations show that the lateral geometry exhibits high electrical conductivity for a wide range of PC parameters and allows for precise control over current flow, enabling efficient carrier injection despite fast surface recombination. Thermal simulations indicate that the temperature increase during steady-state operation is only 3.3K in nanobeams and 0.29K in L3 defect nanocavities. The results affirm the suitability of lateral doping in PC devices and indicate criteria for further design optimization.

Petykiewicz, Jan; Shambat, Gary; Ellis, Bryan; Vu?kovi?, Jelena

2013-03-01

319

Susceptibility of atomic force microscope cantilevers to lateral forces  

NASA Astrophysics Data System (ADS)

V-shaped cantilevers are used widely in the atomic force microscope (AFM) due to their perceived enhanced resistance to lateral forces in comparison to rectangular cantilevers. In this article, we rigorously investigate this premise, and in so doing establish that, contrary to established operating principles and intuition, V-shaped AFM cantilevers are generally more prone to the effects of lateral forces than rectangular AFM cantilevers. This finding suggests that rectangular cantilevers should be used in place of V-shaped cantilevers in applications where the effects of lateral forces are to be minimized.

Sader, John Elie

2003-04-01

320

Small-molecule screens to study lateral root development.  

PubMed

Development of the root system is essential for proper plant growth and development. Extension of the root system is achieved by the continuous establishment of new meristems in existing parental root tissues, which leads to the development of lateral roots. This process of lateral root organogenesis consists of different developmental stages, which are all controlled by the plant hormone auxin. In this chapter, we describe a screening method in Arabidopsis thaliana to identify small synthetic molecules that interfere with the process of lateral root development during specific developmental stages. PMID:23299676

Audenaert, Dominique; De Rybel, Bert; Nguyen, Long; Beeckman, Tom

2013-01-01

321

Measurement of lateral chromatic aberration by using an imaging spectrometer  

NASA Astrophysics Data System (ADS)

Lateral chromatic aberration or lateral color refers to the change in image position with wavelength, and so to the change in magnification, at the image plane of an optical system. In an imaging spectrometer, this introduces a slop and/or curvature in the spectral image line of an object point, a feature that is known as keystone. The variation in keystone when the spectrometer is illuminated with and without the optical system under test allows measuring the lateral chromatic aberration in a wide spectral band.

González-Núñez, Héctor; Prieto-Blanco, Xesús; López Lago, Elena; Mouriz, M. Dolores; de La Fuente, Raúl

2011-05-01

322

11. CONTINUATION OF LATERAL LEAVING THE DIVERSION STRUCTURE WEST OF ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

11. CONTINUATION OF LATERAL LEAVING THE DIVERSION STRUCTURE WEST OF LOWER DERBY LAKE (SECTION 2), SHOWING MEASURING GAUGE. - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

323

Building the posterior lateral line system in zebrafish  

PubMed Central

The posterior lateral line in zebrafish has emerged as an excellent system to study how a sensory organ system develops. Here we review recent studies that illustrate how interactions between multiple signaling pathways coordinate cell fate, morphogenesis and collective migration of cells in the posterior lateral line primordium. These studies also illustrate how the posterior lateral line system is contributing much more broadly to our understanding of mechanisms operating during the growth, regeneration and self-organization of other organ systems during development and disease.

Chitnis, Ajay B; Nogare, Damian Dalle; Matsuda, Miho

2012-01-01

324

Lateral Thinking About Leptin: A Review of Leptin Action via the Lateral Hypothalamus  

PubMed Central

The lateral hypothalamic area (LHA) was initially described as a “feeding center” but we are now beginning to understand that the LHA contributes to other aspects of physiology as well. Indeed, the best-characterized neuronal populations of the LHA (which contain melanin-concentrating hormone (MCH) or the hypocretins/orexins (OX) are not strictly orexigenic, but also have roles in regulation of the autonomic and sympathetic nervous systems as well as in modulating motivated behavior. Leptin is an anorectic hormone that regulates energy homeostasis and the mesolimbic DA system (which transduces the wanting of food, drugs of abuse and sex) in part, via actions at the LHA. At least three populations of LHA neurons are regulated by leptin: those containing MCH, OX or the long form of the leptin receptor, LepRb. The emerging picture of leptin interaction with these LHA populations suggests that the LHA is not merely regulating feeding, but is a crucial integrator of energy balance and motivated behavior.

Leinninger, Gina M.

2011-01-01

325

31. THE BRICK BUILDING IS THE FACTORY BEFORE LATER ADDITIONS, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

31. THE BRICK BUILDING IS THE FACTORY BEFORE LATER ADDITIONS, LOOKING NORTHWEST. TAKEN CIRCA 1886-90, PHOTOGRAPHER UNKNOWN. - Ybor Cigar Factory, 1916 North Fourteenth Street, Tampa, Hillsborough County, FL

326

Alzheimer's Disease: Managing the Later Stages in the Home.  

National Technical Information Service (NTIS)

A multi-media package consisting of a videotape and a presentor's guide. The videotape provides caregivers with information to help them effectively manage problems associated with the later stages of alzheimer's disease in the home environment. It addres...

1994-01-01

327

11. VIEW OF SOUTH BRIDGE PIER, BOTTOM LATERAL BRACING, LOWER ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

11. VIEW OF SOUTH BRIDGE PIER, BOTTOM LATERAL BRACING, LOWER CHORD, STRINGERS, END POST AND BEARING SEAT; FACING SOUTHEAST. - Walker Bridge, Spanning Klamath River in Klamath National Forest, Klamath River, Siskiyou County, CA

328

14. VIEW OF LOG BRIDGE (LATER SUPERSEDED BY THE WIREROPE ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

14. VIEW OF LOG BRIDGE (LATER SUPERSEDED BY THE WIRE-ROPE SUSPENSION BRIDGE), SHOWING OVERHANG WHERE ROCK WAS BLASTED OUT, LOOKING SOUTHWEST - Goat Trail Mining Road, Highway 20, 1.5 miles North of Newhalem, Newhalem, Whatcom County, WA

329

13. VIEW OF LOG BRIDGE (LATER SUPERSEDED BY THE WIREROPE ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

13. VIEW OF LOG BRIDGE (LATER SUPERSEDED BY THE WIRE-ROPE SUSPENSION BRIDGE), SHOWING OVERHANG WHERE ROCK WAS BLASTED OUT, LOOKING NORTHEAST - Goat Trail Mining Road, Highway 20, 1.5 miles North of Newhalem, Newhalem, Whatcom County, WA

330

Performance Analysis for Lateral-Line-Inspired Sensor Arrays.  

National Technical Information Service (NTIS)

The lateral line is a critical component of the fish sensory system, affecting aspects of behavior including maneuvering in complex fluid environments, schooling, and prey tracking. This sensory organ has no analog in ocean vehicles and could fill the gap...

V. I. Fernandez

2011-01-01

331

13. DETAIL, LATERAL BRACING FOR INTERIOR OVERHEAD CRANE Delaware, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

13. DETAIL, LATERAL BRACING FOR INTERIOR OVERHEAD CRANE - Delaware, Lackawanna & Western Railroad Freight & Rail Yard, Multiple Unit Light Inspection Shed, New Jersey Transit Hoboken Terminal Rail Yard, Hoboken, Hudson County, NJ

332

22. Top Lateral Bracing & Top Chord, Vertical Tension Member ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

22. Top Lateral Bracing & Top Chord, Vertical Tension Member 6, end Vertical Compression Members 5 & 4; South Swing Span; looking N. - Pacific Shortline Bridge, U.S. Route 20,spanning Missouri River, Sioux City, Woodbury County, IA

333

[Amyotrophic lateral sclerosis, a disease with a complex diagnosis].  

PubMed

Amyotrophic lateral sclerosis is a degenerative disease with no known cause, no specific presenting symptoms and which results in incapacity and disability. Diagnosis is often delayed. Multi-disciplinary care is essential. PMID:23477081

Catteau, Aurélie; Février, Michelle; Khoumri, Katia; Rabec, Claudio; Giroud, Maurice

2013-02-01

334

On the importance of encapsulation environment for lateral gauges  

NASA Astrophysics Data System (ADS)

In principle, embedded wire-element lateral manganin pressure gauges allow the lateral component of stress during shock loading to be directly monitored. However, such gauges require target materials to be sectioned before insertion into an encapsulating MylarTM/epoxy layer, leading to debate over their analysis. In particular, recent computational modelling has suggested that, amongst other factors, gauge response may be linked to the nature of material flow within the encapsulation under shock loading. Here, this phenomenon was experimentally and computationally investigated by variation of the geometric environment of embedded lateral T-gauges (Vishay Micro-Measurements® type J2M-SS-580SF-025) in Tantalum (Ta) targets. In particular, inclusion of high impedance backing plates allowed restriction of encapsulation material flow under shock. Subsequent comparison to hydrocode simulations provided additional insights into lateral gauge interpretation.

Painter, Jonathan David; Appleby-Thomas, Gareth James; Hazell, Paul; Winter, Ron; Harris, Ernest Joseph; Owen, Gareth D.; Wood, David Christopher

2012-03-01

335

Theoretical Lateral Stability Investigation of a Towed Vehicle  

Microsoft Academic Search

A theoretical method is presented for solving the problem of lateral stability of a towed aircraft. Numerous calculations were made on an electronic digital computer to determine the effect of pertinent parameters on stability.

Popper

1958-01-01

336

Lateral Line Sense Organs and Their Importance in Fish Behavior.  

National Technical Information Service (NTIS)

Attention is mainly devoted to clarifying the structure of the lateral line organs, from the embryo and larva to the fingerling and the sexually mature fish. The study of structure was correlated with experiments concerned with bringing out the adaptation...

N. N. Disler

1971-01-01

337

23. TEMPORARY CENTRIFUGAL PUMP. NOTE CHAPMAN HYDRAULICOPERATED VALVE FOR LATER ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

23. TEMPORARY CENTRIFUGAL PUMP. NOTE CHAPMAN HYDRAULIC-OPERATED VALVE FOR LATER CONNECTION OF ENGINE PUMP ENG TO DISCHARGE HEADER. - Lakeview Pumping Station, Clarendon & Montrose Avenues, Chicago, Cook County, IL

338

38. VIEW LOOKING SOUTH, LATERAL ELEVATION OF CARETAKER'S COTTAGE FROM ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

38. VIEW LOOKING SOUTH, LATERAL ELEVATION OF CARETAKER'S COTTAGE FROM ENTRANCE HOUSE TERRACE (4' x 5' negative) - Fairmount Waterworks, East bank of Schuylkill River, Aquarium Drive, Philadelphia, Philadelphia County, PA

339

Lateral force measurement using a probe fiber as a microlens  

NASA Astrophysics Data System (ADS)

We present a lateral force sensing method for small lateral forces that uses an optical fiber probe as a microlens and measures displacement of the laser spot on a position sensitive detector. We demonstrate that arranging the focus point near the object focal point of the fiber improves the signal intensity and our method combined with synchronous detection can provide a detection limit of the order of 1 pm at a bandwidth of 1 Hz. This indicates that the method enables us to measure lateral force of the order of 1 pN. The method is not restricted by measurement frequency as is the case with tuning fork-based lateral force sensing, and will be a useful method in applications that aim to clarify the intermolecular interaction between the probe and sample by measuring the frequency response, such as nanotribology, nanorheology, interfacial science, and nanobiology.

Fukuzawa, K.; Itoh, S.; Ando, T.; Takahashi, K.; Zhang, H.; Mitsuya, Y.

2004-05-01

340

Childhood Abuse Linked to Later Thyroid Problems for Women  

MedlinePLUS

... sharing features on this page, please enable JavaScript. Childhood Abuse Linked to Later Thyroid Problems for Women ... HealthDay News) -- Women who suffered physical abuse during childhood are at increased risk for thyroid problems, according ...

341

45 CFR 602.51 - Later disallowances and adjustments.  

Code of Federal Regulations, 2012 CFR

...Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND COOPERATIVE AGREEMENTS TO STATE AND LOCAL GOVERNMENTS After-the-Grant Requirements § 602.51 Later...

2012-10-01

342

45 CFR 602.51 - Later disallowances and adjustments.  

Code of Federal Regulations, 2011 CFR

...Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND COOPERATIVE AGREEMENTS TO STATE AND LOCAL GOVERNMENTS After-the-Grant Requirements § 602.51 Later...

2011-10-01

343

4. Photocopy of measured drawing, ca. 1880, LATERAL SECTION, OIL ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. Photocopy of measured drawing, ca. 1880, LATERAL SECTION, OIL ROOM AND CISTERN SECTION, SPECIFICATIONS FOR PLUMBING FIXTURES - Faro de las Cabezas de San Juan, Cabezas de San Juan, Las Croabas, Fajardo Municipio, PR

344

A lateral approach to lower eyelid entropion repair.  

PubMed

The authors describe a simple technique that highlights the use of the sagittal anatomy of the lower eyelid to aid identification of the retractors during involutional entropion repair. This anatomy is exposed following lateral canthotomy and inferior cantholysis. The orbital septum is seen to enclose the fat pad and fuse with the retractors above it prior to insertion into the tarsus. The septum, orbicularis, and skin are incised from the lateral approach, allowing exposure of the retractors for tarsal reattachment, and the procedure is completed with a lateral tarsal strip. Forty-eight procedures in 42 patients with involutional entropion were performed using this technique and 90% and 89% of primary and recurrent entropion, respectively, were successfully repaired. Mean operating time was 30 minutes. The lateral approach to a standard procedure for entropion repair can reduce operating time and technical difficulty. PMID:21902165

Then, Siew-Yin; Salam, Aysha; Kakizaki, Hirohiko; Malhotra, Raman

2011-09-08

345

Roadway Failure Study No. Ii. Lateral Cracking of Asphaltic Concrete.  

National Technical Information Service (NTIS)

The purpose of this investigation has been to examine the relationship of asphalt aging to the alteration of mix properties and to the variation in frequency of lateral cracking of asphaltic concrete pavements. At three field test sites temperature record...

D. R. Lamb W. G. Scott R. H. Gietz J. D. Armijo

1967-01-01

346

Distant touch hydrodynamic imaging with an artificial lateral line.  

PubMed

Nearly all underwater vehicles and surface ships today use sonar and vision for imaging and navigation. However, sonar and vision systems face various limitations, e.g., sonar blind zones, dark or murky environments, etc. Evolved over millions of years, fish use the lateral line, a distributed linear array of flow sensing organs, for underwater hydrodynamic imaging and information extraction. We demonstrate here a proof-of-concept artificial lateral line system. It enables a distant touch hydrodynamic imaging capability to critically augment sonar and vision systems. We show that the artificial lateral line can successfully perform dipole source localization and hydrodynamic wake detection. The development of the artificial lateral line is aimed at fundamentally enhancing human ability to detect, navigate, and survive in the underwater environment. PMID:17132735

Yang, Yingchen; Chen, Jack; Engel, Jonathan; Pandya, Saunvit; Chen, Nannan; Tucker, Craig; Coombs, Sheryl; Jones, Douglas L; Liu, Chang

2006-11-28

347

Laterally Overgrown Structures as Substrates for Lattice Mismatched Epitaxy.  

National Technical Information Service (NTIS)

This article provides a general review of epitaxial lateral overgrowth (ELO) technology and of the application of ELO layers as substrates with an adjustable value of lattice constant. In particular, the issues of ELO growth mechanism, substrate defect fi...

Z. R. Zytkiewicz

2002-01-01

348

Spatial Abilities, Sex Differences, and Lateral Eye Movements.  

ERIC Educational Resources Information Center

|Reports two studies which examined the relationship among (1) the ability to determine horizontality, (2) a general test of spatial abilities, and (3) hemispheric activation as measured by lateral eye movements. (JMB)|

Ray, William J.; And Others

1979-01-01

349

Occurrence of Amyotropic Lateral Sclerosis Among Gulf War Veterans.  

National Technical Information Service (NTIS)

Context. A nation wide epidemiological investigation was undertaken in response to Gulf War Veterans' concerns of high rates of amyotrophic lateral sclerosis (ALS). To determine if Gulf War veterans have an elevated rate of ALS.

R. D. Homer K. G. Kamins J. R. Feussner S. C. Grambow J. Hoff-Lindquist

2002-01-01

350

Lateral Casimir Force Between Deeply Corrugated Dielectric and Metallic Plates  

NASA Astrophysics Data System (ADS)

We study the lateral Casimir force between corrugated dielectric plates. We use the dielectric contrast perturbation theory [R. Golestanian, Phys. Rev. Lett. 95, 230601, (2005)], which allows us to consider arbitrary deformations with large amplitudes. We consider sinusoidal, rectangular, and sawtooth corrugations, for samples made of silicon and gold. We use the plasma and Drude-Lorentz models for the permittivity of gold and silicon, respectively. For these geometries and materials, the lateral Casimir force is not a sinusoidal function of the relative lateral displacement of plates when the gap between the plates in comparable with the depth of the corrugations. Our results facilitate the design of miniaturized devices based on lateral Casimir forces.

Azari, Arash; Miri, Mirfaez

351

51. photocopy of Indian figure which later was mounted on ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

51. photocopy of Indian figure which later was mounted on Tower. Photograph taken at Tacony Iron and Metal Co. works, c. 1892. PCA - The New Public Buildings, Penn Square, Broad & Market Streets, Philadelphia, Philadelphia County, PA

352

52. photocopy of bronze eagle which later was mounted on ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

52. photocopy of bronze eagle which later was mounted on Tower. Photograph taken at Tacony Iron and Metal Co. works, c. 1892. PCA - The New Public Buildings, Penn Square, Broad & Market Streets, Philadelphia, Philadelphia County, PA

353

Differential Braking for Limited-Authority Lateral Maneuvering.  

National Technical Information Service (NTIS)

This IDEA project designed a differential (side-to-side) braking system for limited authority lateral maneuvering that can support active ITS vehicle control systems aimed at preventing unintended road departure events. The vehicle is steered left or righ...

C. C. MacAdam R. D. Erin

2000-01-01

354

Distant touch hydrodynamic imaging with an artificial lateral line  

PubMed Central

Nearly all underwater vehicles and surface ships today use sonar and vision for imaging and navigation. However, sonar and vision systems face various limitations, e.g., sonar blind zones, dark or murky environments, etc. Evolved over millions of years, fish use the lateral line, a distributed linear array of flow sensing organs, for underwater hydrodynamic imaging and information extraction. We demonstrate here a proof-of-concept artificial lateral line system. It enables a distant touch hydrodynamic imaging capability to critically augment sonar and vision systems. We show that the artificial lateral line can successfully perform dipole source localization and hydrodynamic wake detection. The development of the artificial lateral line is aimed at fundamentally enhancing human ability to detect, navigate, and survive in the underwater environment.

Yang, Yingchen; Chen, Jack; Engel, Jonathan; Pandya, Saunvit; Chen, Nannan; Tucker, Craig; Coombs, Sheryl; Jones, Douglas L.; Liu, Chang

2006-01-01

355

11. Detail of sway braces, struts and top lateral braces' ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

11. Detail of sway braces, struts and top lateral braces' view to north-northwest - Milk River Bridge, Spanning Milk River approximately one mile north of Tampico on Tampico North Road, Tampico, Valley County, MT

356

29. DECK / WEB / LATERAL BRACING DETAIL OF CANTILEVER ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

29. DECK / WEB / LATERAL BRACING DETAIL OF CANTILEVER ARM OF THROUGH TRUSS. VIEW TO WEST. - MacArthur Bridge, Spanning Mississippi River on Highway 34 between IA & IL, Burlington, Des Moines County, IA

357

Lateral jets improve PDC bit performance in the North Sea  

SciTech Connect

Lateral nozzles built into specially manufactured polycrystalline diamond compact (PDC) bits improve hydraulics at the bit face, thereby increasing penetration rates. The new bit manufacturing process, investment casting, uses a unique body material for PDC drill bits, allowing design freedom for a lateral-jet-hydraulics concept. Lateral jets set into the blades of the bit improve the cutter cleaning efficiency. In addition to cleaning the slot in front of the blade, the jet creates a venturi effect drawing the fluid across the blades serviced by the downward jets. This flow is then ejected at high speed to the junk slots. Increased efficiency of cutter cleaning can directly improve the rate of penetration (ROP). The paper discusses investment casting; drill bits; lateral jet design; initial concept; hydraulics; flow visualization; and results from Beryl field in U.K. Block 9/13 in the northern North Sea.

Lewis, J. (BBL Brit Bit Ltd., Aberdeen (United Kingdom)); Dacre, A. (Mobil North Sea Ltd., Aberdeen (United Kingdom))

1994-06-20

358

Free lateral arm osteocutaneous neurosensory flap for thumb reconstruction.  

PubMed

Three cases are described to illustrate the use of the lateral arm osteocutaneous neurosensory flap in thumb reconstruction. The merits of such a method and its place in the repertoire of techniques for this problem are discussed. PMID:1779151

Arnez, Z M; Kersnic, M; Smith, R W; Godina, M

1991-11-01

359

Delta-Notch Lateral Inhibition within the Organ of Corti  

NASA Astrophysics Data System (ADS)

Lateral inhibition is described as an emergent property of the Delta-Notch signalling network. Two separate model representations of lateral inhibition are proposed for different purposes. One provides information about bioenergetics while the other has the capability to produce a physical representation. It is proposed that both can be used in further studies of the sensory pathways in the human connectome model of brain function.

Summers, R.; Abdulla, T.; Luff, R.

2013-09-01

360

Hydrodynamics of undulatory fish schooling in lateral configurations  

Microsoft Academic Search

The thrust benefits of lateral configurations of two-dimensional undulating\\u000afish-like bodies are investigated using high-fidelity numerical simulation. The\\u000asolution of the Navier--Stokes equations is carried out with a viscous vortex\\u000aparticle method. Configurations of tethered pairs of fish arranged side by side\\u000aare studied by varying the lateral separation distance and relative phase\\u000adifference. It is shown that, in mirroring

Li Jeany Zhang; Jeff D. Eldredge

2010-01-01

361

Hydrodynamics of undulatory fish schooling in lateral configurations  

Microsoft Academic Search

The thrust benefits of lateral configurations of two-dimensional undulating fish-like bodies are investigated using high-fidelity numerical simulation. The solution of the Navier--Stokes equations is carried out with a viscous vortex particle method. Configurations of tethered pairs of fish arranged side by side are studied by varying the lateral separation distance and relative phase difference. It is shown that, in mirroring

Li Jeany Zhang; Jeff D. Eldredge

2010-01-01

362

How important is lateral masking in visual search?  

Microsoft Academic Search

Five experiments are presented, providing empirical support of the hypothesis that the sensory phenomenon of lateral masking\\u000a may explain many well-known visual search phenomena that are commonly assumed to be governed by cognitive attentional mechanisms.\\u000a Experiment I showed that when the same visual arrays are used in visual search and in lateral masking experiments, the factors\\u000a (1) number of distractors,

A. H. Wertheim; I. T. C. Hooge; K. Krikke; A. Johnson

2006-01-01

363

Morphological asymmetry and behavioral laterality in the crayfish, Procambarus clarkii  

Microsoft Academic Search

Lateral asymmetry is found widely among vertebrates, but is scarcely observed in invertebrates. Here, morphological asymmetry\\u000a and behavioral laterality of a wild crayfish, Procambarus clarkii, was investigated. The carapace morphology of crayfish showed left–right differences; in some, the right side of the carapace\\u000a was larger than the left side, while in others, the left side was larger. A bimodal distribution

Shoko Tobo; Yuichi Takeuchi; Michio Hori

364

Face-hand laterality in relation to personality  

Microsoft Academic Search

398 individuals were observed for lateral asymmetry of the face while smiling involuntarily. About one-fifth showed a well-defined lateral hyperactivity. These were divided into two groups: those with right-handed and right-faced or left-handed and left-faced dominance, and those with contralateral hand-face dominance. In studying the personalities of the members of these two groups, it was found that the ipsilateral hand-face

J. G. Lynn; D. R. Lynn

1938-01-01

365

Maternal Interactive Behaviour in Early Infancy and Later Attachment  

Microsoft Academic Search

Evolutionary considerations (cf. MacDonald, 1992) suggest that emotional closeness and security of attachment address different functional systems. We assume that maternal sensitivity during early face-to-face interactions is related to later emotional closeness, whereas the contingency of maternal reactions towards the infant’s signals is related to later security of attachment. Forty-three mother-infant dyads were videotaped at home during face-to-face interactions when

Susanne Völker; Heidi Keller; Arnold Lohaus; Martina Cappenberg; Athanasios Chasiotis

1999-01-01

366

Alsin and the Molecular Pathways of Amyotrophic Lateral Sclerosis  

Microsoft Academic Search

Autosomal recessive mutations in the ALS2 gene lead to a clinical spectrum of motor dysfunction including juvenile onset amyotrophic lateral sclerosis (ALS2), primary\\u000a lateral sclerosis, and hereditary spastic paraplegia. The 184-kDa alsin protein, encoded by the full-length ALS2 gene, contains three different guanine-nucleotide-exchange factor-like domains, which may play a role in the etiology of\\u000a the disease. Multiple in vitro biochemical

Jayanth Chandran; Jinhui Ding; Huaibin Cai

2007-01-01

367

Lateral diffusion of saturated phosphatidylcholines in cholesterol-containing bilayers  

Microsoft Academic Search

A pulsed field gradient NMR was used to study lateral diffusion in the cholesterol-containing oriented bilayers of saturated\\u000a (dipalmitoyl- and dimyristoyl-) phosphatidylcholines, upon their limiting hydration. Similar dependences of lateral diffusion\\u000a coefficients on temperature and cholesterol concentration were observed, which agree with phase diagram showing the presence\\u000a of the regions of disordered and ordered liquid-crystalline phases and a two-phase region.

A. V. Filippov; M. A. Rudakova; G. Oradd; G. Lindblom

2007-01-01

368

Effects of a manual therapy technique in experimental lateral epicondylalgia  

Microsoft Academic Search

In patients with lateral epicondylalgia, mobilization-with-movement (MWM) is used as an intervention aimed at achieving analgesia and enhancing grip force, although the mechanisms underlying these effects are unclear. The present study investigated the acute sensory and motor effects of an MWM intervention in healthy controls with experimentally induced lateral epicondylalgia. Twenty-four subjects were randomly allocated to either a MWM or

Helen Slater; Lars Arendt-Nielsen; Anthony Wright; Thomas Graven-Nielsen

2006-01-01

369

Smart Skins: Information Processing by Lateral Line Flow Sensors  

Microsoft Academic Search

The information processing capabilities of the lateral line system and its potential utility in surveying foreign environments and providing sensory guidance to autonomous vehicles in dark or highly turbulent conditions is reviewed. The lateral line is a spatially-distributed system of directionally-sensitive sensors that respond to low-frequency water motions created by nearby moving sources, the animal's own movements, the ambient motions

Sheryl Coombs

2001-01-01

370

CEREBRAL LATERALIZATION OF UNFAMILIAR MUSIC PERCEPTION IN NONMUSICIANS  

Microsoft Academic Search

Patterns of cerebral lateralization of unfamiliar music were examined in a group of nonmusicians. A dual-task design procedure that controls for attentional tradeoff effects in a concurrent motor and music processing task was used to determine laterality effects. A pattern of asymmetric interference for melody perception of unfamiliar music was observed among 20 right-handed, musically naive subjects. Signiftcant right-hand tapping

Richard C. LaBarba; Sheryl A. Kingsberg; Patricia K. Martin

1992-01-01

371

Lateral Diffusion of Membrane Proteins at Cell Membrane  

NASA Astrophysics Data System (ADS)

The cell membrane is an important organ of living cells, which has a complex structure influenced by the interaction between membrane proteins and cell membrane. On the basis of fluid motion and diffusion interaction, a simple model is proposed to evaluate quantitatively the effects of the protein size and membrane fluid velocity on the lateral diffusion of membrane proteins at the cell membrane. The study shows that the diffusion coefficient is a dominant factor on the lateral diffusion.

Fan, Lei; Fan, Tian You

372

Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

373

Discoid lateral meniscus: diagnosis and results of arthroscopic treatment  

Microsoft Academic Search

We evaluated the results of arthroscopic meniscectomy in patients with discoid lateral menisci of the knee. Discoid lateral menisci were detected in 308 patients, of whom 197 (124 males, 73 females; mean age 34.5 years, range 6-67) were clinically, radiologically, and arthroscopically found to be symptomatic and underwent partial meniscectomy. The average period between injury and operation was 13.2 months

Mehmet Asik; Cengiz Sen; Omer F. Taser; Aziz K. Alturfan; Yunus V. Sozen

2003-01-01

374

Lateral diffusion in equimolar mixtures of natural sphingomyelins with dioleoylphosphatidylcholine.  

PubMed

Cellular membranes of mammals are composed of a complex assembly of diverse phospholipids. Sphingomyelin (SM) and phosphatidylcholine (PC) are important lipids of eukaryotic cellular membranes and neuronal tissues, and presumably participate in the formation of membrane domains, known as "rafts," through intermolecular interaction and lateral microphase decomposition. In these two-dimensional membrane systems, lateral diffusion of lipids is an essential dynamic factor, which might even be indicative of lipid phase separation process. Here, we used pulsed field gradient nuclear magnetic resonance to study lateral diffusion of lipid components in macroscopically oriented bilayers composed of equimolar mixtures of natural SMs of egg yolk, bovine brain, bovine milk and dipalmitoylphosphatidylcholine (DPPC) with dioleoylphosphatidylcholine (DOPC). In addition, differential scanning calorimetry was used as a complementary technique to characterize the phase state of the lipid bilayers. In fully liquid bilayers, the lateral diffusion coefficients in both DOPC/DPPC and DOPC/SM systems exhibit mean values of the pure bilayers. For DOPC/SM bilayer system, this behavior can be explained by a model where most SM molecules form short-lived lateral domains with preferential SM-SM interactions occurring within them. However, for bilayers in the presence of their low-temperature gel phase, lateral diffusion becomes complicated and cannot simply be understood solely by a simple change in the liquid phase decomposition. PMID:22260936

Filippov, Andrey; Munavirov, Bulat; Gröbner, Gerhard; Rudakova, Maya

2012-01-17

375

Hydrocode analysis of lateral stress gauges in shocked tantalum  

SciTech Connect

Experiments published by other workers, on the resistance change of manganin stress gauges embedded in a lateral orientation in tantalum targets shocked to a range of stresses, have been analysed using an adaptive mesh refinement hydrocode. It was found that for all of the four experiments the shape of the time profile of the computed lateral stress in the mounting layer closely matched the shape of the experimental lateral stress profiles. However, the calculated lateral stresses at the gauge location in the mounting layer are significantly less than the lateral stresses that would have been produced in the target if no gauge had been present. The perturbation caused by the gauge increased as the strength of the applied shock increased. When the perturbations are taken into account values of flow stress that are significantly smaller than those reported in the original research paper are derived. The work shows that the lateral gauge technique can give valuable information on strength provided high resolution simulation is used to compensate for the perturbations caused by the gauges.

Harris, E. J.; Winter, R. E. [Hydrodynamics Division, AWE, Aldermaston, Reading, Berkshire, RG7 4PR (United Kingdom)

2007-12-12

376

SPATACSIN mutations cause autosomal recessive juvenile amyotrophic lateral sclerosis.  

PubMed

The mutation of the spatacsin gene is the single most common cause of autosomal recessive hereditary spastic paraplegia with thin corpus callosum. Common clinical, pathological and genetic features between amyotrophic lateral sclerosis and hereditary spastic paraplegia motivated us to investigate 25 families with autosomal recessive juvenile amyotrophic lateral sclerosis and long-term survival for mutations in the spatascin gene. The inclusion criterion was a diagnosis of clinically definite amyotrophic lateral sclerosis according to the revised El Escorial criteria. The exclusion criterion was a diagnosis of hereditary spastic paraplegia with thin corpus callosum in line with an established protocol. Additional pathological and genetic evaluations were also performed. Surprisingly, 12 sequence alterations in the spatacsin gene (one of which is novel, IVS30 + 1 G > A) were identified in 10 unrelated pedigrees with autosomal recessive juvenile amyotrophic lateral sclerosis and long-term survival. The countries of origin of these families were Italy, Brazil, Canada, Japan and Turkey. The variants seemed to be pathogenic since they co-segregated with the disease in all pedigrees, were absent in controls and were associated with amyotrophic lateral sclerosis neuropathology in one member of one of these families for whom central nervous system tissue was available. Our study indicates that mutations in the spatascin gene could cause a much wider spectrum of clinical features than previously recognized, including autosomal recessive juvenile amyotrophic lateral sclerosis. PMID:20110243

Orlacchio, Antonio; Babalini, Carla; Borreca, Antonella; Patrono, Clarice; Massa, Roberto; Basaran, Sarenur; Munhoz, Renato P; Rogaeva, Ekaterina A; St George-Hyslop, Peter H; Bernardi, Giorgio; Kawarai, Toshitaka

2010-01-28

377

Lockhart Clarke's contribution to the description of amyotrophic lateral sclerosis.  

PubMed

The definition of the clinicopathological entity of amyotrophic lateral sclerosis evolved over half a century. Although the definitive term amyotrophic lateral sclerosis that acknowledged both upper and lower motor neuron involvement was attributed to Jean-Martin Charcot in 1874, his initial case was published nearly a decade earlier; and it is accepted that, from at least the 1830s, several others (including Charles Bell, François-Amilcar Aran and Jean Cruveilhier) had already recognized a progressive lower motor neuron-only syndrome within a broader, clinically-defined group of disorders, termed progressive muscular atrophy. Although William Gowers first grouped the three phenotypes of amyotrophic lateral sclerosis, progressive muscular atrophy and progressive bulbar palsy together as part of the same syndrome, the term motor neuron disease, as an over-arching label, was not suggested until nearly a century later by W. Russell Brain. Augustus Jacob Lockhart Clarke (1817-80) is best known for his descriptions of spinal cord anatomy. However, in two detailed case reports from the 1860s, he carried out rigorous post-mortem neuropathological studies of what appear to be classical cases of amyotrophic lateral sclerosis. Furthermore, he recognized the additional involvement of the corticospinal tracts that distinguished this from progressive muscular atrophy. Several aspects of the exquisite clinical histories documented as part of both studies, one by Charles Bland Radcliffe, resonate with contemporary debates concerning the evolution of disease in amyotrophic lateral sclerosis. These 'past masters' still have much to teach us. PMID:20576696

Turner, Martin R; Swash, Michael; Ebers, George C

2010-06-24

378

Explaining Function with Anatomy: Language Lateralization and Corpus Callosum Size  

PubMed Central

The anatomy of the corpus callosum (CC) has been advocated as a potential marker for functional lateralization because its size is supposedly proportional to the number of fibers connecting the hemispheres. Previous morphometric studies of this relationship have compared CC size in groups of subjects who are more or less likely to show differences in their lateralization (e.g., left vs right handers). The findings, however, have been inconsistent, and to our knowledge, no previous study has directly compared CC size with lateralization assessed by functional imaging data. We therefore combined anatomical measurements of CC size with left versus right hemisphere language activation in 74 normal subjects. After controlling for perceptual and motor output effects, as well as for global white-matter volume, handedness, gender and age, we found that subjects who had a larger CC showed more left lateralization for language in posterior temporal and inferior frontal regions. Examination of these effects revealed that, as CC size increased, stronger lateralization resulted from more left hemisphere activation in both regions as well as reduced right hemisphere activation in the posterior temporal region. Our observations provide the first clear evidence in normal subjects that the midsagittal surface area of the CC contributes to the degree to which language is functionally lateralized. We discuss the complex interhemispheric processes that might underlie this effect.

Josse, Goulven; Seghier, Mohamed L.; Kherif, Ferath; Price, Cathy J.

2009-01-01

379

Explaining function with anatomy: language lateralization and corpus callosum size.  

PubMed

The anatomy of the corpus callosum (CC) has been advocated as a potential marker for functional lateralization because its size is supposedly proportional to the number of fibers connecting the hemispheres. Previous morphometric studies of this relationship have compared CC size in groups of subjects who are more or less likely to show differences in their lateralization (e.g., left vs right handers). The findings, however, have been inconsistent, and to our knowledge, no previous study has directly compared CC size with lateralization assessed by functional imaging data. We therefore combined anatomical measurements of CC size with left versus right hemisphere language activation in 74 normal subjects. After controlling for perceptual and motor output effects, as well as for global white-matter volume, handedness, gender and age, we found that subjects who had a larger CC showed more left lateralization for language in posterior temporal and inferior frontal regions. Examination of these effects revealed that, as CC size increased, stronger lateralization resulted from more left hemisphere activation in both regions as well as reduced right hemisphere activation in the posterior temporal region. Our observations provide the first clear evidence in normal subjects that the midsagittal surface area of the CC contributes to the degree to which language is functionally lateralized. We discuss the complex interhemispheric processes that might underlie this effect. PMID:19109495

Josse, Goulven; Seghier, Mohamed L; Kherif, Ferath; Price, Cathy J

2008-12-24

380

Lateral Femoral Epicondylar Osteotomy: An Extensile Posterolateral Knee Approach  

PubMed Central

Open exposure of the posterolateral corner of the knee is challenged by limitations of posterolateral ligamentous tissues and posterior neurovascular structures. We have used a modification of a lateral femoral epicondyle osteotomy, described historically for surgical management of posterolateral rotatory instability, as an approach to the posterolateral intraarticular structures. The historic technique for ligamentous reconstruction has been abandoned because its nonanatomic fixation does not restore ligamentous isometry. In this report, osteotomy of a bone block from the lateral femoral epicondyle is used to access the joint space. The lateral collateral ligament is reflected distally and posteriorly through traction on the block. Once the intraarticular disorder has been addressed, the lateral femoral epicondyle is secured in its native, anatomic position, thereby restoring isometry and normal joint mechanics after surgery. This technique has been used successfully to address posterolateral articular disorders on femoral and tibial sides. Postoperative magnetic resonance imaging verified restoration of lateral collateral ligament anatomy. Physical examination at 0° and 30° knee flexion showed clinical stability at all postoperative evaluations through 6 and 10 months followup. Using this technique, intraarticular disorders at the posterolateral corner may be addressed in an open manner with anatomic reduction and preserved postoperative function of the lateral collateral ligament. Level of Evidence: Level V, expert opinion. See the Guidelines for Authors for a complete description of levels of evidence.

Bowers, Andrea L.

2008-01-01

381

Lateral-torsion buckling analysis of partial-laterally restrained thin-walled channel-section beams  

Microsoft Academic Search

This paper presents an analytical model for predicting the lateral-torsion buckling of thin-walled channel section beams partial-laterally restrained by metal sheeting when subjected to an uplift load. The critical load is determined by using energy methods. The focus of the study is to investigate the individual influences of moment variation along the longitudinal direction of the beam and of restraints

Xiao-ting Chu; Roger Kettle; Long-yuan Li

2004-01-01

382

Lateral Flagella and Swarming Motility in Aeromonas Species  

PubMed Central

Swarming motility, a flagellum-dependent behavior that allows bacteria to move over solid surfaces, has been implicated in biofilm formation and bacterial virulence. In this study, light and electron microscopic analyses and genetic and functional investigations have shown that at least 50% of Aeromonas isolates from the species most commonly associated with diarrheal illness produce lateral flagella which mediate swarming motility. Aeromonas lateral flagella were optimally produced when bacteria were grown on solid medium for ?8 h. Transmission and thin-section electron microscopy confirmed that these flagella do not possess a sheath structure. Southern analysis of Aeromonas reference strains and strains of mesophilic species (n = 84, varied sources and geographic regions) with a probe designed to detect lateral flagellin genes (lafA1 and lafA2) showed there was no marked species association of laf distribution. Approximately 50% of these strains hybridized strongly with the probe, in good agreement with the expression studies. We established a reproducible swarming assay (0.5% Eiken agar in Difco broth, 30°C) for Aeromonas spp. The laf-positive strains exhibited vigorous swarming motility, whereas laf-negative strains grew but showed no movement from the inoculation site. Light and scanning electron microscopic investigations revealed that lateral flagella formed bacterium-bacterium linkages on the agar surface. Strains of an Aeromonas caviae isolate in which lateral flagellum expression was abrogated by specific mutations in flagellar genes did not swarm, proving conclusively that lateral flagella are required for the surface movement. Whether lateral flagella and swarming motility contribute to Aeromonas intestinal colonization and virulence remains to be determined.

Kirov, Sylvia M.; Tassell, Bronwen C.; Semmler, Annalese B. T.; O'Donovan, Lisa A.; Rabaan, Ali A.; Shaw, Jonathan G.

2002-01-01

383

Hemispheric lateralization of verbal and spatial working memory during adolescence.  

PubMed

Adult functional magnetic resonance imaging (fMRI) literature suggests that a left-right hemispheric dissociation may exist between verbal and spatial working memory (WM), respectively. However, investigation of this type has been obscured by incomparable verbal and spatial WM tasks and/or visual inspection at arbitrary thresholds as means to assess lateralization. Furthermore, it is unclear whether this hemispheric lateralization is present during adolescence, a time in which WM skills are improving, and whether there is a developmental association with laterality of brain functioning. This study used comparable verbal and spatial WM n-back tasks during fMRI and a bootstrap analysis approach to calculate lateralization indices (LIs) across several thresholds to examine the potential of a left-right WM hemispheric dissociation in healthy adolescents. We found significant left hemispheric lateralization for verbal WM, most notably in the frontal and parietal lobes, as well as right hemisphere lateralization for spatial WM, seen in frontal and temporal cortices. Although no significant relationships were observed between LI and age or LI and performance, significant age-related patterns of brain activity were demonstrated during both verbal and spatial WM. Specifically, increased adolescent age was associated with less activity in the default mode brain network during verbal WM. In contrast, increased adolescent age was associated with greater activity in task-positive posterior parietal cortex during spatial working memory. Our findings highlight the importance of utilizing non-biased statistical methods and comparable tasks for determining patterns of functional lateralization. Our findings also suggest that, while a left-right hemispheric dissociation of verbal and spatial WM is apparent by early adolescence, age-related changes in functional activation during WM are also present. PMID:23511846

Nagel, Bonnie J; Herting, Megan M; Maxwell, Emily C; Bruno, Richard; Fair, Damien

2013-03-16

384

Mal-united fracture of calcaneum treated with lateral decompression.  

PubMed

Fracture calcaneum is commonly complicated with mal-union. Mal-union is usually presented with broadening of the lateral wall of the calcaneum, irregularity of the sub-talar joint and loss of the vertical height of the body of calcaneum with varus rotation. In this study twenty three (n=23) patients underwent a lateral decompression for pain on lateral aspect of foot on walking and tip toeing, secondary to a mal-united calcaneal fracture with or without sub-talar intra-articular involvement. Almost every patient had ballooned out body of calcaneum with impingement of peroneal tendon sheath with its content and lateral heel pain as a result of deformity. So in current study the operative procedure selected was excision of a lateral calcaneal bony mass and decompression of the peroneal tendon to relieve pain. Peroneal tenogram was a routine procedure before surgery to detect presence and site of blockade within tendon sheath. The average follow-up was for a period of 31.6 months. Result was assessed according to American Orthopaedic Foot and Ankle Society (AOFAS) Ankle-Hind foot Scale. Two patients (n=2, 8.69%) had excellent (Category 1) result, seventeen (n=17, 73.9%) were good (Category 2), two (n=2, 8.69%) were fair (Category 3) and rest two (n=2, 8.69%) were with poor (Category 4) outcome. Every four out of five patients got back painless Heel and Ankle after surgery. The results suggest that the lateral decompression procedure is a technically simpler yet viable alternative to late sub-talar fusion for lateral pain following a mal-united fracture of calcaneum. PMID:23416823

Bhattacharyya, A; Raman, R

2013-01-01

385

Improved accuracy in Risser sign grading with lateral spinal radiography.  

PubMed

Development of the ossification of the iliac crest is used to assess the remaining spinal growth. The clinical value of the Risser sign has been questioned because of its inaccuracy in grades 3 and 4. Estimation of the Risser sign based on the lateral spinal radiograph has not been reported. The aim of the study was to evaluate the course of ossification of the iliac apophysis along its full extension and to investigate relevance of the lateral spinal radiograph for more accurate Risser sign grading. Cross sectional analysis of spinal frontal and lateral long cassette standing spinal radiographs of 201 girls aged from 10.2 to 20.0 years were done. On the lateral spinal view, the ossification of the posterior part of the iliac apophysis was quantified at four grades: absent (A), partial (B), complete (C) or fused (D). The position of the posterior superior iliac spine was studied on both views as well as in pelvic specimens. The results showed that the posterior one-third portion of the iliac apophysis was sagittally oriented and obscured on the frontal radiograph by the sacroiliac junction. It could be studied on the lateral radiograph and revealed a different grading of the apophysis excursion in 58 of 201 (29%) patients, comparing to the frontal view. Both advanced or delayed ossification was observed and assessed with Lateral Risser Modifiers. Twenty-five percent of the patients at Risser 0 or 1 or 2 demonstrated a simultaneous ossification of the most anterior and the most posterior part of the iliac crest. The Risser grades of capping or fusion could be more precisely diagnosed using lateral radiograph in complement to the frontal one. The conclusions drawn from this study were: (1) Currently used Risser sign grading does not consider the actual excursion of the iliac apophysis, because one-third of the apophysis cannot be observed on the frontal radiograph. (2) Iliac apophysis full excursion or fusion can be more accurately estimated when the lateral spinal radiograph is analyzed with Lateral Risser Modifiers. PMID:18946691

Kotwicki, Tomasz

2008-10-23

386

Control of lateral weight-transfer initiation during sitting.  

PubMed

Whereas many researchers have examined the transition from quiet posture to dynamic state, study of the initiation of lateral weight-transfer during sitting has only begun recently. This action is included in many tasks performed in our daily living, i.e., reaching, dressing, looking backwards, lying down, and shuffling the buttocks. The present study was designed to describe lateral weight-transfer movements of healthy adults, kinematically and kinetically, and to clarify the strategies and speed dependency of lateral weight-transfer initiation during sitting. Seven healthy Japanese male students without orthopaedic or neurological disorders participated. Their lateral weight-transfer movements were measured during sitting, using two force platforms and a 3-dimensional analysis system. Analysis showed that there appear to be two strategies for the initiation of the task: one is the lateral bending of trunk toward the weight-transfer side, and the other is a coordinated reciprocal leg action of both legs. A combination of these strategies is used in a trade-off fashion during natural motions. These results are clinically important for the assessment and therapy of patients with sitting problems. PMID:15446657

Sekiya, Noboru; Takahashi, Masaaki

2004-08-01

387

Dynamic interplay between adhesive and lateral E-cadherin dimers.  

PubMed

E-cadherin, an adhesive transmembrane protein of epithelial adherens junctions, forms two types of detergent-resistant dimers: adhesive dimers consisting of cadherin molecules derived from two neighboring cells and lateral dimers incorporating cadherins of the same cell. Both dimers depend on the integrity of the same residue, Trp156. While the relative amounts of these complexes are not certain, we show here that in epithelial A-431 cells, adhesive dimers may be a prevalent form. Inactivation of the calcium-binding sites, located between successive cadherin ectodomains, drastically reduced the amount of adhesive dimers and concomitantly increased the amount of lateral dimers. A similar interdependence of adhesive and lateral dimers was observed in digitonin-permeabilized cells. In these cells, adhesive dimers immediately disassembled after lowering the Ca2+ concentration below 0.1 mM. The disappearance of adhesive dimers was counterbalanced by an increase in Trp156-dependent lateral dimers. Increasing the calcium concentration to a normal level rapidly restored the original balance between adhesive and lateral dimers. We also present evidence that E-cadherin dimers in vivo have a short lifetime. These observations suggest that cadherin-mediated adhesion is based on the dynamic cycling of E-cadherin between monomeric and adhesive dimer states. PMID:12370292

Klingelhöfer, Jörg; Laur, Oscar Y; Troyanovsky, Regina B; Troyanovsky, Sergey M

2002-11-01

388

Dynamic Interplay between Adhesive and Lateral E-Cadherin Dimers  

PubMed Central

E-cadherin, an adhesive transmembrane protein of epithelial adherens junctions, forms two types of detergent-resistant dimers: adhesive dimers consisting of cadherin molecules derived from two neighboring cells and lateral dimers incorporating cadherins of the same cell. Both dimers depend on the integrity of the same residue, Trp156. While the relative amounts of these complexes are not certain, we show here that in epithelial A-431 cells, adhesive dimers may be a prevalent form. Inactivation of the calcium-binding sites, located between successive cadherin ectodomains, drastically reduced the amount of adhesive dimers and concomitantly increased the amount of lateral dimers. A similar interdependence of adhesive and lateral dimers was observed in digitonin-permeabilized cells. In these cells, adhesive dimers immediately disassembled after lowering the Ca2+ concentration below 0.1 mM. The disappearance of adhesive dimers was counterbalanced by an increase in Trp156-dependent lateral dimers. Increasing the calcium concentration to a normal level rapidly restored the original balance between adhesive and lateral dimers. We also present evidence that E-cadherin dimers in vivo have a short lifetime. These observations suggest that cadherin-mediated adhesion is based on the dynamic cycling of E-cadherin between monomeric and adhesive dimer states.

Klingelhofer, Jorg; Laur, Oscar Y.; Troyanovsky, Regina B.; Troyanovsky, Sergey M.

2002-01-01

389

Polarization anomaly of Love waves caused by lateral heterogeneity  

NASA Astrophysics Data System (ADS)

We calculate surface waves propagating in a laterally heterogeneous structure beneath the Kuril trench, where significant Love-wave polarization anomalies, called quasi-Love waves, are generated. Since 3-D wave propagation in the two-dimensionally heterogeneous structure can be assumed, we apply the 2.5-D finite difference method to the surface-wave calculations. The calculations show that a velocity contrast of 7 per cent at depths of less than 210 km beneath the Kuril trench cannot generate quasi-Love waves, and that an unlikely contrast of 20 per cent is required to generate clear quasi-Love waves. The possible cause of the quasi-Love waves inferred from previous studies on coupled free oscillations is a lateral variation in azimuthal anisotropy. The lateral variation in azimuthal anisotropy beneath the Kuril trench suggests a change in the mantle flow induced by the subducting slab.

Kobayashi, Reiji

1998-12-01

390

Vehicle Lateral State Estimation Based on Measured Tyre Forces  

PubMed Central

Future active safety systems need more accurate information about the state of vehicles. This article proposes a method to evaluate the lateral state of a vehicle based on measured tyre forces. The tyre forces of two tyres are estimated from optically measured tyre carcass deflections and transmitted wirelessly to the vehicle body. The two remaining tyres are so-called virtual tyre sensors, the forces of which are calculated from the real tyre sensor estimates. The Kalman filter estimator for lateral vehicle state based on measured tyre forces is presented, together with a simple method to define adaptive measurement error covariance depending on the driving condition of the vehicle. The estimated yaw rate and lateral velocity are compared with the validation sensor measurements.

Tuononen, Ari J.

2009-01-01

391

Representation of negative motivational value in the primate lateral habenula  

PubMed Central

An action may lead to a reward or punishment. Therefore, an appropriate action needs to be chosen based on the values of both expected rewards and expected punishments. To understand the underlying neural mechanisms we conditioned monkeys using a Pavlovian procedure with two distinct contexts: one in which rewards were available, and another in which punishments were feared. We found that the population of lateral habenula neurons were most strongly excited by a conditioned stimulus associated with the most unpleasant event in each context: the absence of the reward or the presence of the punishment. The population of lateral habenula neurons were also excited by the punishment itself and inhibited by the reward itself, especially when they were less predictable. These results suggest that the lateral habenula has the potential to adaptively control both reward-seeking and punishment-avoidance behaviors, presumably through its projections to dopaminergic and serotonergic systems.

Matsumoto, Masayuki; Hikosaka, Okihide

2009-01-01

392

Dysembryoplastic neuroepithelial tumor in the left lateral ventricle.  

PubMed

Extracortical location of dysembryoplastic neuroepithelial tumor (DNT) is rare. We present a case of DNT localized in the left lateral ventricle of a 21-year-old female patient. Magnetic resonance imaging of the brain showed a round mass lesion in the floor of the anterior horn of the left lateral ventricle. The lesion was hypointense on T (1)-weighted images and slightly hyperintense on T (2)-weighted images without contrast enhancement. Total removal of the yellowish-white colored soft tumor was performed through a transcallosal approach. Histologically, the tumor was of simple type of DNT that was composed of small oligodendrogliocytes clustered tightly about perivascular spaces with neurons floating in mucoid pools showing an eosinophilic fibrillary matrix in the background. The recognition of DNT with an unusual location in lateral ventricle has therapeutic and prognostic significance since DNT is curable by surgical excision and radiation therapy is of no obvious benefit. PMID:14628248

Ongürü, O; Deveci, S; Sirin, S; Timurkaynak, E; Günhan, O

2003-10-01

393

Axially accelerated saboted rods subjected to lateral forces  

SciTech Connect

Considerable effort has been dedicated to ensuring the structural integrity of long rods during axial acceleration, but little work has addressed the subject of lateral acceleration of the sabot/rod package while it is still in-bore. Drysdale states ''Certainly the most pressing unsolved problem facing the projectile designer at the present time does not involve structural integrity directly. Rather it is the development of a methodology which allows the rational design of in-bore configurations so that balloting and sabot separations have a minimal effect on the flight of the subprojectile.'' Characterization of the response of sabot/rod systems to lateral loading is the next fundamental step to improving sabot designs. Benchmarked analyses and methodology will provide projectile designers with both quantitative and qualitative information to characterize the structural integrity of sabots that are subjected to lateral loads during launch. 10 refs., 12 figs.

Rabern, D.A.

1989-01-01

394

Measurement of the lateral compressibility of several phospholipid bilayers.  

PubMed Central

Lateral compressibilities of bilayers in multilayer lattices are given for 10 phospholipid preparation:dilauryl-, dimyristoyl-, dipalmitoyl-, distearoyl-, and dioleoylphosphatidylcholine (PC); egg phosphatidylethanolamine (PE); as well as cholesterol-containing bilayers of dipalmitoyl PC or of egg PC. Bilayer deformability is highly nonlinear and does not permit description in terms of a simple modulus. The presence of cholesterol or C=C bonds (dioleoyl PC) increases deformability, but freezing of acyl chains does not cause dramatic stiffening of the bilayer. Lateral compression of dilauryl PC an dimyristoyl PC causes a transition from "melted" to "frozen" acyl chains above the normal transition temperatures. Our measurements do not correspond in any obvious way to lateral compressibilities in monolayers at the air-water interface.

Lis, L J; McAlister, M; Fuller, N; Rand, R P; Parsegian, V A

1982-01-01

395

Lateral buttock and postanal congenital dermal sinus tract.  

PubMed

We present 2 rare cases of lateral buttock and postanal congenital dermal sinus tract. These 2 children were noted to have a pit in the left upper lateral buttock and a postanal orifice after birth. Magnetic resonance imaging, computed tomography, and ultrasonography showed an inflammatory mass lesion in the buttock and a funicular structure adjacent to the rectum. Fistulography showed no connection between the pit and orifice. Surgical exploration revealed firm tracts from both the lateral buttock and postanus running deep to the tip of the coccyx. Histopathologic findings showed squamous cells in the walls of the sinus tracts. Our report broadens the clinical literature regarding congenital dermal sinus tract. We postulate that this disease may not always have a connection with the central nervous system, and our cases may provide examples of anal fistulas of congenital etiology in infants. PMID:20438910

Qi, Shiqin; Zheng, Jicui; Lü, Zhibao; Li, Kai; Chen, Lian; Xiao, Xianmin

2010-05-01

396

Issues Related to Lateral Stress Measurements in Alumina Ceramics  

NASA Astrophysics Data System (ADS)

Failure fronts or ``waves'' in brittle materials have been the subject of extensive research. This is a phenomenon where a damage front propagates behind the main shock wave and reduces the strength. It is reported to be observed by means of embedded lateral gauges where it manifests itself as a two-step structure. Such profiles were obtained when impacts were performed using copper flyers. Later, it was shown that this second rise in lateral stress was not evident in ceramic targets when either a ceramic projectile plate was employed or a thin ceramic cover plate was mounted on the front of the target. We now extend the use of different projectile materials such as heat treated 4340 steel and tungsten. We find that the second step is not evident and may instead be an effect of the experimental parameters and not related to the failure front.

Field, J. E.; Tsembelis, K.; Brar, N. S.; Proud, W. G.; Dandekar, D. P.; Rosenberg, Z.

2004-07-01

397

Displacement of maxillary third molar into the lateral pharyngeal space.  

PubMed

Iatrogenic tooth displacement is a rare complication during extraction of impacted molars, but displacement of a maxillary third molar into the maxillary sinus, infratemporal fossa, buccal space, pterygomandibular space, and lateral pharyngeal space has been reported. Currently, 6 published reports describe third molar displacement into the lateral pharyngeal space, only 1 of which involved the loss of a maxillary third molar into this area, which occurred after an attempted self-extraction by the patient. There have been no reported cases of iatrogenic displacement of the maxillary third molar during an extraction procedure. This article describes the recovery, under general anesthesia, of a maxillary third molar from the lateral pharyngeal space after an iatrogenic displacement. PMID:23890786

Lee, Doksa; Ishii, Syoichiro; Yakushiji, Noboru

2013-07-24

398

Experimental and computational investigation of lateral gauge response in polycarbonate  

NASA Astrophysics Data System (ADS)

The shock behaviour of polycarbonate is of interest due to its extensive use in defence applications. Interestingly, embedded lateral manganin stress gauges in polycarbonate have shown gradients behind incident shocks, suggestive of increasing shear strength. However, such gauges are commonly embedded in a central epoxy interlayer. This is an inherently invasive approach. Recently, research has suggested that in such systems interlayer/target impedance may contribute to observed gradients in lateral stress. Here, experimental T-gauge (Vishay Micro-Measurements® type J2M-SS-580SF-025) traces from polycarbonate targets are compared to computational simulations. The effects of gauge environment are investigated by looking at the response of lateral gauges with both standard "glued-joint" and a "dry joint" encapsulation, where no encapsulating medium is employed.

Eliot, Jim; Harris, Ernest Joseph; Hazell, Paul; Appleby-Thomas, Gareth James; Winter, Ron; Wood, David Christopher

2012-03-01

399

Orienting asymmetries and lateralized processing of sounds in humans  

PubMed Central

Background Lateralized processing of speech is a well studied phenomenon in humans. Both anatomical and neurophysiological studies support the view that nonhuman primates and other animal species also reveal hemispheric differences in areas involved in sound processing. In recent years, an increasing number of studies on a range of taxa have employed an orienting paradigm to investigate lateralized acoustic processing. In this paradigm, sounds are played directly from behind and the direction of turn is recorded. This assay rests on the assumption that a hemispheric asymmetry in processing is coupled to an orienting bias towards the contralateral side. To examine this largely untested assumption, speech stimuli as well as artificial sounds were presented to 224 right-handed human subjects shopping in supermarkets in Germany and in the UK. To verify the lateralized processing of the speech stimuli, we additionally assessed the brain activation in response to presentation of the different stimuli using functional magnetic resonance imaging (fMRI). Results In the naturalistic behavioural experiments, there was no difference in orienting behaviour in relation to the stimulus material (speech, artificial sounds). Contrary to our predictions, subjects revealed a significant left bias, irrespective of the sound category. This left bias was slightly but not significantly stronger in German subjects. The fMRI experiments confirmed that the speech stimuli evoked a significant left lateralized activation in BA44 compared to the artificial sounds. Conclusion These findings suggest that in adult humans, orienting biases are not necessarily coupled with lateralized processing of acoustic stimuli. Our results – as well as the inconsistent orienting biases found in different animal species – suggest that the orienting assay should be used with caution. Apparently, attention biases, experience, and experimental conditions may all affect head turning responses. Because of the complexity of the interaction of factors, the use of the orienting assay to determine lateralized processing of sound stimuli is discouraged.

Fischer, Julia; Teufel, Christoph; Drolet, Matthis; Patzelt, Annika; Rubsamen, Rudolf; von Cramon, D Yves; Schubotz, Ricarda I

2009-01-01

400

Dynamic biomechanics of the human head in lateral impacts.  

PubMed

The biomechanical responses of human head (translational head CG accelerations, rotational head accelerations, and HIC) under lateral impact to the parietal-temporal region were investigated in the current study. Free drop tests were conducted at impact velocities ranging from 2.44 to 7.70 m/s with a 40 durometer, a 90 durometer flat padding, and a 90 durometer cylinder. Specimens were isolated from PMHS subjects at the level of occipital condyles, and the intracranial substance was replaced with brain simulant (Sylgard 527). Three tri-axial accelerometers were instrumented at the anterior, posterior, and vertex of the specimen, and a pyramid nine accelerometer package (pNAP) was used at the contra-lateral site. Biomechanical responses were computed by transforming accelerations measured at each location to the head CG. The results indicated significant "hoop effect" from skull deformation. Translational head CG accelerations were accurately measured by transforming the pNAP, the vertex accelerations, or the average of anterior/posterior acceleration to the CG. The material stiffness and structural rigidity of the padding changed the biomechanical responses of the head with stiffer padding resulting in higher head accelerations. At the skull fracture, HIC values were more than 2-3x higher than the frontal skull fracture threshold (HIC=1000), emphasizing the differences between frontal and lateral impact. Rotational head accelerations up to 42.1 krad/s(2) were observed before skull fracture, indicating possible severe brain injury without skull fracture in lateral head impact. These data will help to establish injury criteria and threshold in lateral impacts for improved automotive protection and help clinicians understand the biomechanics of lateral head impact from improved diagnosis. PMID:20184848

Zhang, Jiangyue; Yoganandan, Narayan; Pintar, Frank A

2009-10-01

401

Dynamic biomechanics of the human head in lateral impacts  

PubMed Central

The biomechanical responses of human head (translational head CG accelerations, rotational head accelerations, and HIC) under lateral impact to the parietal-temporal region were investigated in the current study. Free drop tests were conducted at impact velocities ranging from 2.44 to 7.70 m/s with a 40 durometer, a 90 durometer flat padding, and a 90 durometer cylinder. Specimens were isolated from PMHS subjects at the level of occipital condyles, and the intracranial substance was replaced with brain simulant (Sylgard 527). Three tri-axial accelerometers were instrumented at the anterior, posterior, and vertex of the specimen, and a pyramid nine accelerometer package (pNAP) was used at the contra-lateral site. Biomechanical responses were computed by transforming accelerations measured at each location to the head CG. The results indicated significant “hoop effect” from skull deformation. Translational head CG accelerations were accurately measured by transforming the pNAP, the vertex accelerations, or the average of anterior/posterior acceleration to the CG. The material stiffness and structural rigidity of the padding changed the biomechanical responses of the head with stiffer padding resulting in higher head accelerations. At the skull fracture, HIC values were more than 2–3x higher than the frontal skull fracture threshold (HIC=1000), emphasizing the differences between frontal and lateral impact. Rotational head accelerations up to 42.1 krad/s2 were observed before skull fracture, indicating possible severe brain injury without skull fracture in lateral head impact. These data will help to establish injury criteria and threshold in lateral impacts for improved automotive protection and help clinicians understand the biomechanics of lateral head impact from improved diagnosis.

Zhang, Jiangyue; Yoganandan, Narayan; Pintar, Frank A.

2009-01-01

402

Biomechanics of lateral plate and pedicle screw constructs in lumbar spines instrumented at two levels with laterally placed interbody cages.  

PubMed

BACKGROUND CONTEXT: The lateral transpsoas approach to interbody fusion is gaining popularity because of its minimally invasive nature and resultant indirect neurologic decompression. The acute biomechanical stability of the lateral approach to interbody fusion is dependent on the type of supplemental internal fixation used. The two-hole lateral plate (LP) has been approved for clinical use for added stabilization after cage instrumentation. However, little biomechanical data exist comparing LP fixation with bilateral pedicle screw and rod (PSR) fixation. PURPOSE: To biomechanically compare the acute stabilizing effects of the two-hole LP and bilateral PSR fusion constructs in lumbar spines instrumented with a lateral cage at two contiguous levels. STUDY DESIGN: Biomechanical laboratory study of human cadaveric lumbar spines. METHODS: Eighteen L1-S1 cadaveric lumbar spines were instrumented with lateral cages at L3-L4 and L4-L5 after intact kinematic analysis. Specimens (n=9 each) were allocated for supplemental instrumentation with either LP or PSR. Intact versus instrumented range of motion was evaluated for all specimens by applying pure moments (±7.5 Nm) in flexion/extension, lateral bending (LB) (left+right), and axial rotation (AR) (left+right). Instrumented spines were later subjected to 500 cycles of loading in all three planes, and interbody cage translations were quantified using a nonradiographic technique. RESULTS: Lateral plate fixation significantly reduced ROM (p<.05) at both lumbar levels (flexion/extension: 49.5%; LB: 67.3%; AR: 48.2%) relative to the intact condition. Pedicle screw and rod fixation afforded the greatest ROM reductions (p<.05) relative to the intact condition (flexion/extension: 85.6%; LB: 91.4%; AR: 61.1%). On average, the largest interbody cage translations were measured in both fixation groups in the anterior-posterior direction during cyclic AR. CONCLUSIONS: Based on these biomechanical findings, PSR fixation maximizes stability after lateral interbody cage placement. The nonradiographic technique served to quantify migration of implanted hardware and may be implemented as an effective laboratory tool for surgeons and engineers to better understand mechanical behavior of spinal implants. PMID:23685215

Nayak, Aniruddh N; Gutierrez, Sergio; Billys, James B; Santoni, Brandon G; Castellvi, Antonio E

2013-05-16

403

Localization - Delocalization Transition of Indirect Excitons in Lateral Electrostatic Lattices  

NASA Astrophysics Data System (ADS)

We report on a study of transport of indirect excitons in GaAs/AlGaAs coupled quantum wells in linear lateral lattices created by laterally modulated gate voltage. The localization-delocalization transition for the excitons was observed with increasing density in the directions along and across the lattice. At high lattice amplitudes, the density corresponding to the transition across the lattice was found to linearly depend on the lattice amplitude. Screening of the potential by repulsive exciton-exciton interaction was demonstrated.

Remeika, M.; Graves, J.; Hammack, A. T.; Butov, L. V.; Hanson, M.; Gossard, A. C.

2009-03-01

404

Meningioma in the Lateral Cerebellomedullary Cistern without Dural Attachment  

PubMed Central

A 59-year-old female presented with headache and dizziness for one year. Magnetic resonance imaging revealed a 52 × 28 mm, well-circumscribed, homogenously enhancing mass lesion without dural attachment located in the left lateral cerebellomedullary cistern. The tumor was excised, and a histological diagnosis was a mixed pattern meningioma of meningothelial and fibroblastic type. A meningioma in the posterior fossa without dural attachment is quite rare. We report a rare case of lateral cerebellomedullary cistern meningioma without dural attachment with literature review.

Kim, Seong Min; Jung, Sung Sam; Park, Moon Sun

2010-01-01

405

Lateral variation of target poisoning during reactive magnetron sputtering  

NASA Astrophysics Data System (ADS)

The reactive gas incorporation into a Ti sputter target has been investigated using laterally resolving ion beam analysis during dc magnetron deposition of TiN in an Ar/N2 atmosphere. At sufficiently low reactive gas flow, the nitrogen incorporation exhibits a pronounced lateral variation, with a lower areal density in the target racetrack compared to the target center and edge. The findings are reproduced by model calculations. In the racetrack, the balance of reactive gas injection and sputter erosion is shifted toward erosion. The injection of nitrogen is dominated by combined molecular adsorption and recoil implantation versus direct ion implantation.

Güttler, D.; Grötzschel, R.; Möller, W.

2007-06-01

406

Lateral Shift Makes a Ground-Plane Cloak Detectable  

NASA Astrophysics Data System (ADS)

We examine the effectiveness of the ground-plane invisibility cloak generated from quasiconformal mapping of electromagnetic space. This cloak without anisotropy will generally lead to a lateral shift of the scattered wave, whose value is comparable to the height of the cloaked object, making the object detectable. This can be explained by the fact that the corresponding virtual space is thinner and wider than it should be. Ray tracing on a concrete model shows that, for a bump with a maximum height of 0.2 units to be hidden, the lateral shift of a ray with 45° incidence is around 0.15 units.

Zhang, Baile; Chan, Tucker; Wu, Bae-Ian

2010-06-01

407

Lateral dominance and visual evoked potentials in albinos.  

PubMed

Lateral preferences for the use of eye, hand, and foot were assessed in 17 male and female albino subjects, aged 15 to 52 yr. Visual evoked potential (VEP) recordings suggested that optic fibres were abnormally decussated in these subjects, as others have shown. Fewer albino subjects showed the lateral preference for the use of hand/eye and foot/eye similar to that of normals. It is postulated that the abnormal decussation of optic fibres may underlie the reduced preference for the use of the same hand and eye, and foot and eye, in albinos. PMID:3725523

Murdoch, B D; Reef, H E

1986-06-01

408

Muscle ultrasonography to predict survival in amyotrophic lateral sclerosis.  

PubMed

The authors assessed the prognostic value of muscle ultrasonography in 31 patients with amyotrophic lateral sclerosis (ALS) and compared it with accepted prognostic variables like functional capacity (measured with the Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)) and muscle strength. Each patient was examined once. The following ultrasonography parameters were determined: muscle thickness, echo intensity (EI) and the presence of fasciculations. Correlations between baseline measurements, preslope values and survival were calculated. EI, disease duration, muscle strength preslope and ALSFRS-R preslope correlated with survival. Using a stepwise multivariate analysis, the combination of EI preslope and ALSFRS-R preslope was shown to have the best predictive value for survival. PMID:20392981

Arts, Ilse M P; Overeem, Sebastiaan; Pillen, Sigrid; Schelhaas, Helenius Jurgen; Zwarts, Machiel J

2010-04-14

409

Entrapment of the lateral cutaneous nerve of the calf.  

PubMed

Isolated lesion of lateral cutaneous nerve of the calf (LCNC), particularly due to entrapment, is rarely reported in the literature. Patients usually present with sensory symptoms in the lateral aspect of the calf. Treatment is usually by local applications or local steroid/anaesthetic injection. We report the first case of LCNC entrapment in a 35-year-old man which is documented by nerve conduction studies. The patient had a temporary improvement following a local anaesthetic/steroid injection. Owing to the recurrence of symptoms, the patient opted for surgery. About 1 year after surgery, the symptoms disappeared completely. PMID:23821626

Khalil, Nofal M; Nicotra, Alessia; Kaplan, Charles; O'Neill, Kevin S

2013-07-02

410

Doppler-based lateral motion tracking for optical coherence tomography.  

PubMed

Nonuniform lateral scanning of the probe beam in optical coherence tomography produces imaging artifacts and leads to a morphologically inaccurate representation of the sample. Here, we demonstrate a solution to this problem, which is based on the Doppler shift carried by the complex-valued depth-resolved scattering amplitude. Furthermore, we demonstrate the feasibility of Doppler flow velocity measurements in underlying flow channels while laterally scanning the imaging probe over large surfaces with arbitrary and varying velocity. Finally, we performed centimeters-long hand-held B-mode imaging of skin in vivo. PMID:22739861

Weiss, Nicolás; van Leeuwen, Ton G; Kalkman, Jeroen

2012-06-15

411

LATERAL GENE TRANSFER AND THE HISTORY OF BACTERIAL GENOMES  

SciTech Connect

The aims of this research were to elucidate the role and extent of lateral transfer in the differentiation of bacterial strains and species, and to assess the impact of gene transfer on the evolution of bacterial genomes. The ultimate goal of the project is to examine the dynamics of a core set of protein-coding genes (i.e., those that are distributed universally among Bacteria) by developing conserved primers that would allow their amplification and sequencing in any bacterial taxa. In addition, we adopted a bioinformatic approach to elucidate the extent of lateral gene transfer in sequenced genome.

Howard Ochman

2006-02-22

412

Using the pressuremeter curve to design laterally loaded piles  

SciTech Connect

The P-y curve is a soil model used in the design of laterally loaded piles. A method is presented to obtain the P-y curve from the pressuremeter curve. This method distinguishes between the friction model and the front resistance model. Using this approach, comparisons are made between the predicted and measured behavior of two laterally loaded piles; one in a soft clay and one in a medium to dense sand. The comparisons show very good agreement and point out that a distinction may have to be made between displacement piles and non displacement piles.

Briaud, J.; Meyer, B.J.; Smith, T.D.

1983-05-01

413

Preemptive use of palliative sedation and amyotrophic lateral sclerosis.  

PubMed

Patients in the advanced stages of amyotrophic lateral sclerosis often are faced with the dilemma of whether to use or continue to use mechanical ventilation. Patients who elect to terminate ventilatory support may be subject to significant and even extreme respiratory symptoms. Severe dyspnea and other symptoms are sometimes treated with palliative sedation, which is generally recommended as a last resort approach to refractory symptoms. However, the preemptive use of palliative sedation is sometimes appropriate. The preemptive use of palliative sedation is examined through a case-based analysis of a patient with advanced amyotrophic lateral sclerosis. PMID:22464355

Berger, Jeffrey T

2012-04-01

414

Laterality in coiling behaviour of snakes: another interpretation.  

PubMed

The direction of coiling was periodically recorded for two species of viperid snakes--copperheads (Agkistrodon contortrix) and cottonmouths (Agkistrodon piscivorus). Overall, neither species showed a significant preference for coiling in a particular direction. Only 1 of 22 snakes exhibited an individual preference, a result within expectation for random direction of coiling when using a 5% rejection level for statistical testing. A previously published claim for laterality in coiling direction by cottonmouths presented similar results but came to the opposite conclusion. The data from the combined studies suggest that if laterality in coiling direction does occur, it is extremely weak and inconsistent. PMID:17852698

Heatwole, Harold; King, Peter; Levine, Samuel G

2007-11-01

415

Cyriax physiotherapy for tennis elbow\\/lateral epicondylitis  

Microsoft Academic Search

Tennis elbow or lateral epicondylitis is one of the most common lesions of the arm with a well defined clinical presentation, which significantly impacts on the community. Many treatment approaches have been proposed to manage this condition. One is Cyriax physiotherapy. The effectiveness and reported effects of this intervention are reviewed.

D Stasinopoulos; M I Johnson

2004-01-01

416

Lateralized brain injury and behavior problems in children  

Microsoft Academic Search

This study investigated the types of behavior problems found in children with lateralized brain lesions. Children referred for neuropsychological assessment were assigned to dominant (DH) or nondominant (NDH) groups on the basis of history of neurological disease or injury, findings on neurological examination, functional and structural laboratory findings, and neuropsychological assessment. Over two-thirds fell into the clinical range of behavior

Natalie D. Sollee; Daniel J. Kindlon

1987-01-01

417

Trauma in Early Infancy and Later Personality Development  

Microsoft Academic Search

The psychodynamic patterns of personality of children born with congenital ob- structions in the alimentary tract were compared with those of normal children in later childhood. The congenital anomalies had required surgery within the first 4 months of life. The psychodynamic patterns were elicited by 4 projective tech- niques. Information regarding the mothers' emotional stability and attitudes was gathered by

RALPH M. GIBSON

418

Communication of direction through lateral skin stretch at the fingertip  

Microsoft Academic Search

A variety of tasks could benefit from the availability of direction cues that do not rely on vision or sound. Skin stretch has been found to be a reliable means of communicating direction and has potential to be rendered by a compact device. We have conducted experiments exploring the use of lateral skin stretch at the fingertip to communicate direction.

Brian T. Gleeson; Scott K. Horschel; William R. Provancher

2009-01-01

419

Future time perspective in later adulthood: Review and research directions  

Microsoft Academic Search

The degree of experimental and quantitative detail which can be imposed on older adults' temporal experiences remains a significant area for investigation. This paper surveys material related to this general area of study, taking primarily a psychological focus. Review of this literature suggests that while a basic future time orientation is not significantly affected in later life, older adults are

William Rakowski

1979-01-01

420

Right Hemisphere Metaphor Processing? Characterizing the Lateralization of Semantic Processes  

ERIC Educational Resources Information Center

|Previous laterality studies have implicated the right hemisphere in the processing of metaphors, however it is not clear if this result is due to metaphoricity per se or another aspect of semantic processing. Three divided visual field experiments varied metaphorical and literal sentence familiarity. We found a right hemisphere advantage for…

Schmidt, Gwen L.; DeBuse, Casey J.; Seger, Carol A.

2007-01-01

421

The lateral ambipolar diffusion length in quantum dot lasers  

Microsoft Academic Search

Using the segmented contact technique we determine the lateral out-diffusion current in shallow etched quantum dot ridges of different width and by fitting this out-diffusion data we obtain the ambipolar diffusion length as a function of the intrinsic carrier injection level. The measured data reveals two regimes of reduced diffusion that can be explained by a mechanism involving the thermal

A. Sobiesierski; D. Naidu; P. M. Smowton

2011-01-01

422

Language Lateralization in Children Using Functional Transcranial Doppler Sonography  

ERIC Educational Resources Information Center

|Aim: Language lateralization with functional transcranial Doppler sonography (fTCD) and lexical word generation has been shown to have high concordance with the Wada test and functional magnetic resonance imaging in adults. We evaluated a nonlexical paradigm to determine language dominance in children. Method: In 23 right-handed children (12…

Haag, Anja; Moeller, Nicola; Knake, Susanne; Hermsen, Anke; Oertel, Wolfgang H.; Rosenow, Felix; Hamer, Hajo M.

2010-01-01

423

TDP43 mutations in familial and sporadic amyotrophic lateral sclerosis  

Microsoft Academic Search

Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disorder characterized pathologically by ubiquitinated TAR DNA binding protein (TDP-43) inclusions. The function of TDP-43 in the nervous system is uncertain, and a mechanistic role in neurodegeneration remains speculative. We identified neighboring mutations in a highly conserved region of TARDBP in sporadic and familial ALS cases. TARDBPM337V segregated with disease within

Jemeen Sreedharan; Ian P. Blair; Vineeta B. Tripathi; Xun Hu; Caroline Vance; Boris Rogelj; Steven Ackerley; Jennifer C. Durnall; Kelly L. Williams; Emanuele Buratti; Francisco Baralle; Jacqueline de Belleroche; J. Douglas Mitchell; P. Nigel Leigh; Ammar Al-Chalabi; Christopher C. Miller; Garth Nicholson; Christopher E. Shaw

2008-01-01

424

Peroneal tendon subluxation: the other lateral ankle injury  

Microsoft Academic Search

Ankle injuries are a frequent cause of patient visits to the emergency department and orthopaedic and primary care offices. Although lateral ligament sprains are the most common pathologic conditions, peroneal tendon subluxations occur with a similar inversion mechanism. Multiple grades of subluxation have been described with a recent addition of intrasheath subluxation. Magnetic resonance imaging is the best imaging modality

Jennifer A Roth; Walter C Taylor; Joseph Whalen

2010-01-01

425

Motivational Factors in Health Promoting Behavior in Later Aging  

Microsoft Academic Search

This study investigated motivational factors in health- promoting behavior in later aging. The participants were 162 members of the Terman Study of the Gifted (82 men and 80 women) who responded to a mailout questionnaire in 1999 at a mean age of 86. The motivational variables included questionnaire measures of the goal to be as healthy as possible, purpose in

Carole K. Holahan; Rie Suzuki

2006-01-01

426

5. Photocopy of site plan drawing, with later amendments dhowing ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. Photocopy of site plan drawing, with later amendments dhowing original USFS building shceduled for removal, Annex moved to present location, and addition to Warehouse (from the U.S. Forest Service, Wenatchee National Forest) Date Unkown - U.S. Forest Service Chelan Ranger Station, 428 West Woodin Avenue, Chelan, Chelan County, WA

427

Lateral pressure over formwork on large dimension concrete blocks  

Microsoft Academic Search

The design of vertical formwork is dependent on the lateral pressure predicted to act on the form face. Experimental research into the construction of blocks on a gravity dam was carried out with the objective of verifying and comparing the adequacy of different theories. Pressure was measured indirectly as the load on the trusses of formwork support, which allows verification

I. Puente; A. Santilli; A. Lopez

2010-01-01

428

Conditioned flavor preference and aversion: Role of the lateral hypothalamus  

Microsoft Academic Search

Food-restricted rats with ibotenic acid lesions of the lateral hypothalamus (LH) and sham controls were trained to associate flavored solutions with positive or negative postingestive consequences. The LH rats learned to prefer a flavor that was paired with concurrent intragastric infusions of maltodextrin. Unlike controls, the LH rats failed to learn a preference for a flavor paired with delayed maltodextrin

Khalid Touzani; Anthony Sclafani

2001-01-01

429

Lateral cervical facetectomy. The surgical pathology of radicular brachialgia  

Microsoft Academic Search

Summary In 113 patients with radicular brachialgia and neuropathy without spinal cord affection surgical treatment consisted in facetectomy and exposure of the extrathecal part of the cervical root from the axilla to the lateral border of the root canal. In 27 patients disc herniation, and in 43 uncovertebral exostosis, was detected. In 59 patients a thick, fibrous periradicular cuff tightened

C. Mosdal; J. Overgaard

1984-01-01

430

Lead Exposure as a Risk Factor for Amyotrophic Lateral Sclerosis  

Microsoft Academic Search

Background: The etiology of amyotrophic lateral sclerosis (ALS) likely involves an environmental component. We qualitatively assessed literature on ALS and lead exposure. Problems of study design make case reports and studies of lead in blood or tissues difficult to interpret. Most previous case-control studies found an association of ALS with self-reported occupational exposure to lead, with increased risks of 2-

F. Kamel; D. M. Umbach; H. Hu; T. L. Munsat; J. M. Shefner; J. A. Taylor; D. P. Sandler

2005-01-01

431

16. View of passage (formerly Spicket Street; later, railroad rightofway) ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

16. View of passage (formerly Spicket Street; later, railroad right-of-way) between Paper Machine Building (on left) and Wilder Mill (on right), from Canal Street; view to north. - Champion-International Paper Company, West bank of Spicket River at Canal Street, Lawrence, Essex County, MA

432

15. View of passage (formerly Spicket Street; later, railroad rightofway) ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

15. View of passage (formerly Spicket Street; later, railroad right-of-way) between Wilder Mill (on left) and Paper Machine Building (on right), showing collapsed area of stone arch bridge spanning raceway in foreground; view to south - Champion-International Paper Company, West bank of Spicket River at Canal Street, Lawrence, Essex County, MA

433

17. View of passage (formerly Spicket Street; later, railroad rightofway) ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

17. View of passage (formerly Spicket Street; later, railroad right-of-way) between Paper Machine Building (on left) and Wilder Mill (on right), from inside security fence; view to north. - Champion-International Paper Company, West bank of Spicket River at Canal Street, Lawrence, Essex County, MA

434

Reimpressed selective breeding for lateralization of handedness in mice  

Microsoft Academic Search

Eleven generations of bidirectional selection for lateralization produced 2 lines of mice that differ markedly in degree of asymmetry for hand preference. The foundation population was derived from 6 distantly related inbred strains and 2 stocks of wild mice, M. castaneus. HI line matings were made using mice that exhibited consistent right or left paw use in a food reaching

R L Collins

1991-01-01

435

Gender and inequalities in health in later life  

Microsoft Academic Search

Little research attention has been given to examining inequalities in the health of elderly women and men, in spite of their high use of health services and the importance of health to maintaining independence in later life. This paper uses data from the British General Household Survey to analyse the variation in health of elderly women and men by class

Sara Arber; Jay Ginn

1993-01-01

436

National Motives Predict Psychogenic Death Rates 25 Years Later  

Microsoft Academic Search

Achievement motivation scores derived from analyses of content of children's stories from 16 countries predicted death rates due to ulcers and hypertension, and power motivation scores predicted death rates due to murder, suicide, and cirrhosis of the liver 25 years later.

S. A. Rudin

1968-01-01

437

Hydrodynamic interactions between laterally-spaced undulating ``fish''  

Microsoft Academic Search

It is generally accepted that fish achieve hydrodynamic benefits by swimming in schools, though the mechanisms used to achieve these benefits are not completely understood. In particular, the influence of lateral separation between fish has not been well characterized. In this work, it is shown that substantial increases in thrust can be obtained by fish swimming in parallel with no

Jeany L. Zhang; Jeff D. Eldredge

2008-01-01

438

Lateral diffusion of H-2 antigens on mouse fibroblasts  

Microsoft Academic Search

We have used fluorescence photobleaching and recovery (FPR) to measure the lateral diffusion of mouse H-2 antigens, labeled with fluorescent Fob fragments, in the membrane of cl ld fibroblasts. Diffusion coefficients, D, vary more than 20-fold from cell to cell, though they vary no more than twofold when measured at different points on a single cell. The fraction of H-2

MICHAEL EDIDIN; TAIYIN WEI

1982-01-01

439

Robust detection of peak signals for lateral flow immunoassays  

Microsoft Academic Search

Template matching method is presented to identify the peaks from the scanned signals of lateral flow immunoassay strips. The template is composed of two pulses separated by the distance of the control and the target ligand line in the assay, and is convolved with the scanned signal to deliver the maximum at the center of the two peaks. The peak

Jongwon Kim; Jong Dae Kim; Kie Bong Nahm; Eui Yul Choi; Geumyoung Lee

2011-01-01

440

Botulinum toxin treatment of lateral axial dystonia in parkinsonism  

Microsoft Academic Search

Lateral axial dystonia (LAD) has been described in patients with Parkinson's disease (PD), but treatment might be more controversial than treatment of LAD in other neurological conditions. Our study was designed as a blinded cross-over with botulinum toxin (BTX) and placebo in order to investigate the efficacy of BTX in PD LAD. Nine patients with LAD who failed to experience

Laura Bonanni; Astrid Thomas; Sara Varanese; Vincenzo Scorrano; Marco Onofrj

2007-01-01

441

Early Speech Perception and Later Language Development: Implications for the \\  

Microsoft Academic Search

In this article, we present a summary of recent research linking speech perception in infancy to later language development, as well as a new empirical study examining that linkage. Infant phonetic discrimination is initially language universal, but a de- cline in phonetic discrimination occurs for nonnative phonemes by the end of the 1st year. Exploiting this transition in phonetic perception

Patricia K. Kuhl; Barbara T. Conboy; Denise Padden; Tobey Nelson; Jessica Pruitt

2005-01-01

442

Importance of Different Power Sources in Downward and Lateral Relations  

Microsoft Academic Search

An exploratory study was conducted to increase knowledge of the types of power used to influence subordinates and peers. The study involved two taxonomies for conceptualizing power, two questionnaires for measuring power, two outcome criteria, two levels of management, and two respondent samples. Innovative features include new power scales, a larger variety of power sources, and measurement of lateral power

Gary Yukl; Cecilia M. Falbe

1991-01-01

443

Transitions into and out of Cohabitation in Later Life  

ERIC Educational Resources Information Center

|Cohabitation among adults over age 50 is rising rapidly, more than doubling from 1.2 million in 2000 to 2.75 million in 2010. A small literature provides a descriptive portrait of older cohabitors, but no study has investigated transitions into and out of cohabitation during later life. Drawing on demographic and life course perspectives, the…

Brown, Susan L.; Bulanda, Jennifer Roebuck; Lee, Gary R.

2012-01-01

444

Radial nerve entrapment by the lateral head of the triceps.  

PubMed

A case of slowly progressive radial nerve entrapment of spontaneous onset is presented. Surgical exploration revealed compression of the radial nerve by a musculotendinous arch of the lateral head of the triceps. Relief of signs and symptoms did not ensue. PMID:1880378

Nakamichi, K; Tachibana, S

1991-07-01

445

Spatiotemporal Coupling of the Tongue in Amyotrophic Lateral Sclerosis  

ERIC Educational Resources Information Center

|Purpose: The primary aim of the investigation was to identify deficits in spatiotemporal coupling between tongue regions in amyotrophic lateral sclerosis (ALS). The relations between disease-related changes in tongue movement patterns and speech intelligibility were also determined. Methods: The authors recorded word productions from 11…

Kuruvilla, Mili S.; Green, Jordan R.; Yunusova, Yana; Hanford, Kathy

2012-01-01

446

Electromyographic patterns of individuals suffering from lateral tennis elbow  

Microsoft Academic Search

This study investigated the applicability of using surface electromyography (EMG) as a tool for differentiating between persons suffering from lateral tennis elbow and the healthy age-matched adults. Temporal muscle activation patterns of the tennis elbow group were evaluated to determine if they varied between subject groups and if noted variations might be interpreted as arresting or exacerbating the injury. Sixteen

Jeffrey A. Bauer; Robert D. Murray

1999-01-01

447

Female preference for male lateral projection area in Poecilia reticulata  

Microsoft Academic Search

The lateral projection area (LPA) hypothesis was investigated by presenting female guppies, Poecilia reticulata with a series of paired males in three experiments. One trait was held constant in each experiment (dorsal fin size in expt\\u000a I, body size in expt II, and total LPA in expt III) while body: dorsal fin ratio varied. Females spent more time near dummies

Ronald David MacLaren; Adam Fontaine

448

Cerebral Laterality Effects in the Dual Processing of Prose.  

ERIC Educational Resources Information Center

|The degree to which concreteness of prose material presented in an auditory fashion would interact with learners' lateral preference under different right hemispheric presentation conditions was investigated with 96 adults. Subjects recalled a greater number of ideas when the passage was concrete. Abstractness interacted with cerebral dominance.…

Dean, Raymond S.

1984-01-01

449

The Development of Hand Laterality in Infantile Autism. Brief Report.  

ERIC Educational Resources Information Center

|A follow-up study of handedness in 34 autistic persons (mean age 8 years) supported the idea that there are many factors other than brain damage, hemispheric functioning, age, and follow-up interval that contribute to hand lateralization. (CL)|

Tsai, Luke Y.

1984-01-01

450

Hemispheric lateralization of singing after intracarotid sodium amylobarbitone1  

Microsoft Academic Search

Hemispheric lateralization of singing was investigated in patients who had transient hemiplegia after intracarotid injection of sodium amylobarbitone. It was found that after right carotid injection singing was markedly deficient, whereas speech remained relatively intact. Songs were sung in a monotone, devoid of correct pitch rendering; rhythm was much less affected. By contrast, singing was less disturbed than speech after

H. W. Gordon; J. E. Bogen

1974-01-01

451

Hemispheric Laterality Differences among Four Levels of Reading Achievement.  

ERIC Educational Resources Information Center

|Twenty words were tachistoscopically presented to the left and right visual half fields of 80 boys (ages 8-10) to determine if incomplete hemispheric laterality is associated with all levels of reading deficiency or only with the more severe cases. (Author/CL)|

Garren, Richard B.

1980-01-01

452

New Investigation of Short Wings with Lateral Jets.  

National Technical Information Service (NTIS)

The lift of short wings by means of lateral fluid jets fired in the plane of the wing in the direction of the span is described. After some theoretical considerations, the experimental results obtained in a wind tunnel on a series of wings of various leng...

E. Carafoli N. Camarasescu

1983-01-01

453

Androgynous Gender Roles in Later Life: Conceptual Critique and Recommendations.  

ERIC Educational Resources Information Center

|Recent theoretical formulations by Gutmann and Sinnott about the nature of men's and women's roles in later life are critiqued on conceptual and empirical grounds. This paper proposes a multidimensional conceptualization of gender role that stresses dynamic linkages between psychological and social psychological levels of analysis. Requisites of…

Wells, Kathleen; McGee, Jeanne

454

Lateral variation of Lg wave propagation in southern Mexico  

Microsoft Academic Search

In this study we investigated lateral variation of Lg wave propagation in southern Mexico from recordings of 92 crustal earthquakes along 591 travel paths. The efficiency of Lg propagation was measured in terms of Lgto Pn spectral ratio. It was found that Lgpropagation is inefficient for travel paths through the Gulf of Mexico coastal plains and the Gulf of Tehuantepec,

Lars Ottemöller; Nikolai M. Shapiro; Shri Krishna Singh; Javier F. Pacheco

2002-01-01

455

Lateral vehicle velocity estimation using fuzzy sliding mode observer  

Microsoft Academic Search

This paper presents a robust method for estimation the lateral velocity of vehicle. The proposed observer describes a simple structure that contains a sliding mode term which turns out to be robust against output noises and parameters variations as well as sustained disturbances The given nonlinear model of the vehicle is then represented by an uncertain Takagi-Sugeno fuzzy model when

Mohammed OUDGHIRI; Mohammed CHADLI; Ahmed El HAJJAJI

2007-01-01

456

Childhood Socioeconomic Status Predicts Physical Functioning a Half Century Later  

Microsoft Academic Search

Background. Socioeconomic status (SES) affects health outcomes at all stages of life. Relating childhood socio- economic environment to midlife functional status provides a life course perspective on childhood factors associated with poor and good health status later in life. Methods. The British 1946 birth cohort was prospectively evaluated with periodic examinations from birth through age 53 years, when physical performance

Jack M. Guralnik; Suzanne Butterworth; Michael E. J. Wadsworth; Diana Kuh

2006-01-01

457

The Effects of Procedural Variations on Lateralized Stroop Effects  

Microsoft Academic Search

Several issues in the classic Stroop effect remain open, including (i) the stage of processing which gives rise to the effect, (ii) the effect of some procedural manipulations, (iii) the effect of hemispheric specialization and of interhemispheric interactions, and (iv) the existence of individual differences. In this paper, we investigate these issues using a series of experiments with central, lateral,

N. Y. Weekes; E. Zaidel

1996-01-01

458

A strip method for lateral drift force of a semisubmersible  

Microsoft Academic Search

This paper presents the results of an application of a strip technique for the prediction of the lateral drift forces on a semisubmersible platform floating in oblique regular waves. The method employs Maruo's formula and source distribution technique, without taking account of the hydrodynamic interaction between the twin hulls and columns of the semisubmersible. Overall the strip technique shows a

C. H. Kim; W. Bao

1985-01-01

459

The efficacy of splinting for lateral epicondylitis: a systematic review  

Microsoft Academic Search

To determine the efficacy of using splinting as a treatment for lateral epicondylitis (LE), a systematic review of the literature was conducted on Medline, Cumulative Index to Nursing and Allied Health Literature (CINAHL), EMBASE, PEDro, and Cochrane databases using pertinent key words and phrases. Hand searches of article references were also used to ensure that as many relevant articles as

Carin D Borkholder; Valerie A Hill; Elaine Ewing Fess

2004-01-01

460

Mixed Lateral Dominance as a Predictive Factor of Learning Disability.  

ERIC Educational Resources Information Center

|This report discusses the outcomes of a study of 147 children (ages 7-10) with learning disabilities that investigated the extent to which students legally classified with learning disabilities concurrently manifested mixed lateral dominance (MLD). The study was conducted to determine if MLD was a possible predictive factor for early…

Powers, P. J.; Putnam, Jon

461

Electroacupuncture reduces neuroinflammatory responses in symptomatic amyotrophic lateral sclerosis model  

Microsoft Academic Search

Amyotrophic lateral sclerosis (ALS) is a paralyzing disorder that is characterized by the progressive degeneration and death of motor neurons. Acupuncture or electroacupuncture (EA) has been used for the treatment of various conditions including osteoarthritis, asthma, and other types of chronic pain conditions. It has been hypothesized that acupuncture exerts anti-inflammatory and anti-nociceptive effects on inflammatory reactions processes. The purpose

Eun Jin Yang; Jing Hua Jiang; Sang Min Lee; Hye Suk Hwang; Myeong Soo Lee; Sun Mi Choi

2010-01-01

462

Perceived Strategies and Activities for Successful Later Aging  

ERIC Educational Resources Information Center

|This study investigated perceived strategies and activities for successful later aging. Participants were 242 members of the Terman Study of the Gifted who responded to an open-ended question concerning how they make the most of their aging years. Data were collected in 1996 and 1999, when the participants were average ages of 84 and 86.…

Holahan, Carole K.; Velasquez, Katherine S.

2011-01-01

463

Amyotrophic Lateral Sclerosis: An Emerging Era of Collaborative Gene Discovery  

Microsoft Academic Search

Amyotrophic lateral sclerosis (ALS) is the most common form of motor neuron disease (MND). It is currently incurable and treatment is largely limited to supportive care. Family history is associated with an increased risk of ALS, and many Mendelian causes have been discovered. However, most forms of the disease are not obviously familial. Recent advances in human genetics have enabled

Katrina Gwinn; Roderick A. Corriveau; Hiroshi Mitsumoto; Kate Bednarz; Robert H. Brown Jr; Merit Cudkowicz; Paul H. Gordon; John Hardy; Edward J. Kasarskis; Petra Kaufmann; Robert Miller; Eric Sorenson; Rup Tandan; Bryan J. Traynor; Josefina Nash; Alex Sherman; Matthew D. Mailman; James Ostell; Lucie Bruijn; Valerie Cwik; Stephen S. Rich; Andrew Singleton; Larry Refolo; Jaime Andrews; Ran Zhang; Robin Conwit; Margaret A. Keller

2007-01-01

464

Lateral wave propagation in a three-layered medium  

NASA Astrophysics Data System (ADS)

The effect of an intervening layer on a lateral wave which propagates along the interface between two different electrical media is considered. The lateral wave travels down from a time-harmonic electric dipole source in the upper region, through the middle region, and parallel to the interface between the middle and lower regions. It is assumed that the magnitude of the wavenumber in the upper medium is much greater than that of the middle, which in turn is much greater than that of the lower. The middle layer affects the lateral wave in two ways. It multiplies the usual lateral wave results by an overall factor which depends on the thickness of the slab and the electrical properties of the three media. It also changes at what distance the transition from intermediate to far field behavior occurs. Typically, the presence of the slab increases the magnitude of the fields near the transmitter, but leads to smaller field strengths in the far field region. The formulas are derived in two ways. The first utilizes an iterative procedure based on impedance boundary conditions and boundary layer theory. The second uses the more traditional steepest descent evaluation of the exact integrals available for the problem.

Dunn, John M.

1986-09-01

465

Lateral Knee Braces in Football: Do They Prevent Injury?  

ERIC Educational Resources Information Center

The results of three recently presented clinical studies and a biomechanical study of the use of lateral knee braces to prevent knee injuries are reviewed. The results raise serious doubts about the efficacy of the preventive knee braces which are currently available. (Author/MT)

Paulos, Lonnie E.; And Others

1986-01-01

466

Marijuana in the management of amyotrophic lateral sclerosis  

Microsoft Academic Search

Marijuana has been proposed as treatment for a widening spectrum of medical conditions. Marijuana is a substance with many properties that may be applicable to the management of amyotrophic lateral sclerosis (ALS). These include analgesia, muscle relaxation, bronchodilation, saliva reduction, appetite stimulation, and sleep induction. In addition, marijuana has now been shown to have strong antioxidative and neuroprotective effects, which

Gregory T. Carter; Bill S. Rosen

2001-01-01

467

Lateral pressure profiles in cholesterol–DPPC bilayers  

Microsoft Academic Search

By means of atomistic molecular dynamics simulations, we study cholesterol–DPPC (dipalmitoyl phosphatidylcholine) bilayers of different composition, from pure DPPC bilayers to a 1:1 mixture of DPPC and cholesterol. The lateral pressure profiles through the bilayers are computed and separated into contributions from the different components. We find that the pressure inside the bilayer changes qualitatively for cholesterol concentrations of about

Michael Patra

2005-01-01

468

Termination of Optic Fibres in the Lateral Geniculate Body  

Microsoft Academic Search

IN a recent letter1, Prof. Le Gros Clark directed attention to the evidence that crossed and uncrossed fibres of the optic tract each terminate in three alternating layers of cells in the lateral geniculate body in the monkey. Hitherto, however, this has been an inference based on the indirect evidence of transneuronal atrophy. It has now been finally established in

P. Glees

1940-01-01

469

Beyond Subjection: Notes on the Later Foucault and Education  

ERIC Educational Resources Information Center

This article argues against the doxa that Foucault's analysis of education inevitably undermines self-originating ethical intention on the part of teachers or students. By attending to Foucault's lesser known, later work--in particular, the notion of "biopower" and the deepened level of materiality it entails--the article shows how the earlier…

Leask, Ian

2012-01-01

470

Lateral Preference Behaviors in Preschool Children and Young Adults.  

ERIC Educational Resources Information Center

The behavioral manifestations of hand, eye, foot, and ear preference were studied in a sample of 384 children of 3, 4, and 5 years of age, and were compared to the preferences of a group of 171 high school students. Results indicate that some aspects of lateral preference behavior are influenced by age-related variables. (Author/RH)

Coren, Stanley; And Others

1981-01-01

471

Social Effectiveness Therapy for Children: Five Years Later  

ERIC Educational Resources Information Center

|Social Effectiveness Therapy for Children (SET-C) is a comprehensive behavioral treatment combining social skills training, peer generalization experiences, and individualized in vivo exposure for the treatment of social phobia in youth. SET-C results in positive treatment outcome and its effects are maintained at least 3 years later. In this…

Beidel, Deborah C.; Turner, Samuel M.; Young, Brennan J.

2006-01-01

472

Speech perception, localization, and lateralization with bilateral cochlear implants  

Microsoft Academic Search

Five bilateral cochlear implant users were tested for their localization abilities and speech understanding in noise, for both monaural and binaural listening conditions. They also participated in lateralization tasks to assess the impact of variations in interaural time delays (ITDs) and interaural level differences (ILDs) for electrical pulse trains under direct computer control. The localization task used pink noise bursts

Richard J. M. van Hoesel; Richard S. Tyler

2003-01-01

473

PATTERNS OF LATER LIFE EDUCATION AMONG TEENAGE MOTHERS  

Microsoft Academic Search

This article uses data from the National Longitudinal Study of Youth to examine the phenomenon of later life education among women who first give birth as teenagers. The analysis first considers patterns of educational attainment through the middle 30s for all women, disaggregated by age at first birth. This allows for an examination of the amount of education received by

LAUREN M. RICH; SUN-BIN KIM

1999-01-01

474

Lateral and Anterior Thalamic Lesions Impair Independent Memory Systems  

ERIC Educational Resources Information Center

Damage to the medial region of the thalamus, both in clinical cases (e.g., patients with infarcts or the Korsakoff's syndrome) and animal lesion models, is associated with variable amnesic deficits. Some studies suggest that many of these memory deficits rely on the presence of lateral thalamic lesions (LT) that include the intralaminar nuclei,…

Mitchell, Anna S.; Dalrymple-Alford, John C.

2006-01-01

475

Juvenile amyotrophic lateral sclerosis with unusual presentation: a case report.  

PubMed

A case of juvenile amyotrophic lateral sclerosis with wasting confined to the distal part of one lower limb and the proximal part of the contralateral upper limb is being presented. A brief review of the literature is carried out. PMID:14652459

Panagariya, A; Garg, A; Sharma, B

2003-09-01

476

Mitochondria in Amyotrophic Lateral Sclerosis: A Trigger and a Target  

Microsoft Academic Search

Strong evidence shows that mitochondrial dysfunction is involved in amyotrophic lateral sclerosis (ALS), but despite the fact that mitochondria play a central role in excitotoxicity, oxidative stress and apoptosis, the intimate underlying mechanism linking mitochondrial defects to motor neuron degeneration in ALS still remains elusive. Morphological and functional abnormalities occur in mitochondria in ALS patients and related animal models, although

Luc Dupuis; Jose-Luis Gonzalez de Aguilar; Hugues Oudart; Marc de Tapia; Luis Barbeito; Jean-Philippe Loeffler

2004-01-01

477

Fatigue of a laterally constrained closed cell aluminum foam  

Microsoft Academic Search

An experimental investigation into the constant stress amplitude compression–compression fatigue behavior of closed-cell aluminum foam, both with and without lateral constraint, was conducted. Results show that while the early stages of strain accumulation due to fatigue loading are independent of constraint, the rapid strain accumulation stage behaviors are sensitive to the constraint. This was ascribed to the noticeable hardening with

M. Kolluri; M. Mukherjee; F. Garcia-Moreno; J. Banhart; U. Ramamurty

2008-01-01

478

Role of gas pressure and lateral stress on blistering  

SciTech Connect

Both gas pressure in bubbles and lateral stress have been suggested as primary causes of blistering. An analysis of both mechanisms is presented, and the conditions for blistering are examined. To realistically predict the gas pressure in bubbles, a recently derived high-density equation of state for helium is utilized.

Wolfer, W.G.

1980-04-01

479

Vehicle lateral guidance using vision, passive wire and radar sensors  

Microsoft Academic Search

Research performed in the area of vehicle lateral guidance using vision, passive wire and radar sensors is described. It is important to compare the feasibility of different sensing systems on a common platform to determine the best alternative that may be integrated in an automated highway system. A test vehicle is equipped with each of three sensors and a common

Mahlon Heller; M. Huie

1993-01-01

480

13. ONE OF TWO LATERAL ROOF TRUSSES AND ROOF SUPPORT ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

13. ONE OF TWO LATERAL ROOF TRUSSES AND ROOF SUPPORT BEAMS OF SARATOGA GAS LIGHT COMPANY GASHOLDER NO. 2 HOUSE LOOKING WEST. THE WIRES AND BEAM AT RIGHT CENTER OF PHOTOGRAPH HAVE BEEN ADDED TO STABILIZE TRUSS SYSTEM - Saratoga Gas Light Company, Gasholder No. 2, Niagara Mohawk Power Corporation Substation Facility, intersection of Excelsior & East Avenues, Saratoga Springs, Saratoga County, NY

481

The Lateralization of Motor Cortex Activation to Action-Words  

PubMed Central

What determines the laterality of activation in motor cortex for words whose meaning is related to bodily actions? It has been suggested that the neuronal representation of the meaning of action-words is shaped by individual experience. However, core language functions are left-lateralized in the majority of both right- and left-handers. It is still an open question to what degree connections between left-hemispheric core language areas and right-hemispheric motor areas can play a role in semantics. We investigated laterality of brain activation using fMRI in right- and left-handed participants in response to visually presented hand-related action-words, namely uni- and bi-manual actions (such as “throw” and “clap”). These stimulus groups were matched with respect to general (hand-) action-relatedness, but differed with respect to whether they are usually performed with the dominant hand or both hands. We may expect generally more left-hemispheric motor cortex activation for hand-related words in both handedness groups, with possibly more bilateral activation for left-handers compared to right-handers. In our study, both participant groups activated motor cortex bilaterally for bi-manual words. Interestingly, both groups also showed a left-lateralized activation pattern to uni-manual words. We argue that this reflects the effect of left-hemispheric language dominance on the formation of semantic brain circuits on the basis of Hebbian correlation learning.

Hauk, Olaf; Pulvermuller, Friedemann

2011-01-01

482

The lateralization of motor cortex activation to action-words.  

PubMed

What determines the laterality of activation in motor cortex for words whose meaning is related to bodily actions? It has been suggested that the neuronal representation of the meaning of action-words is shaped by individual experience. However, core language functions are left-lateralized in the majority of both right- and left-handers. It is still an open question to what degree connections between left-hemispheric core language areas and right-hemispheric motor areas can play a role in semantics. We investigated laterality of brain activation using fMRI in right- and left-handed participants in response to visually presented hand-related action-words, namely uni- and bi-manual actions (such as "throw" and "clap"). These stimulus groups were matched with respect to general (hand-) action-relatedness, but differed with respect to whether they are usually performed with the dominant hand or both hands. We may expect generally more left-hemispheric motor cortex activation for hand-related words in both handedness groups, with possibly more bilateral activation for left-handers compared to right-handers. In our study, both participant groups activated motor cortex bilaterally for bi-manual words. Interestingly, both groups also showed a left-lateralized activation pattern to uni-manual words. We argue that this reflects the effect of left-hemispheric language dominance on the formation of semantic brain circuits on the basis of Hebbian correlation learning. PMID:22144954

Hauk, Olaf; Pulvermüller, Friedemann

2011-11-29

483

Serotype sensitivity of a lateral flow immunoassay for cryptococcal antigen.  

PubMed

To meet the needs of a global community, an immunoassay for cryptococcal antigen (CrAg) must have high sensitivity for CrAg of all major serotypes. A new immunoassay for CrAg in lateral flow format was evaluated and found to have a high sensitivity for detection of serotypes A, B, C, and D. PMID:23365202

Gates-Hollingsworth, Marcellene A; Kozel, Thomas R

2013-01-30

484

Serotype Sensitivity of a Lateral Flow Immunoassay for Cryptococcal Antigen  

PubMed Central

To meet the needs of a global community, an immunoassay for cryptococcal antigen (CrAg) must have high sensitivity for CrAg of all major serotypes. A new immunoassay for CrAg in lateral flow format was evaluated and found to have a high sensitivity for detection of serotypes A, B, C, and D.

Gates-Hollingsworth, Marcellene A.

2013-01-01

485

Dielectric studies of a laterally-linked siloxane ester dimer  

Microsoft Academic Search

This paper reports measurements of the dielectric response over the frequency range 10 to 10?Hz of a liquid crystal dimer consisting of two ester mesogens laterally linked by an alkoxy chain containing a siloxane group. The synthesis and phase behaviour of the siloxane dimer are also reported. Results show that there are two relaxations in the isotropic phase and four

Sergio Diez; M. Rosario De La Fuente; Panagiota K. Karahaliou; Georg Mehl; Thomas Meyer; Miguel Ángel PerÉz Jubindo; Demetri J. Photinos

2003-01-01

486

Effect of lateral perturbations on psychophysical acceleration detection thresholds  

Microsoft Academic Search

BACKGROUND: In understanding how the human body perceives and responds to small slip-like motions, information on how one senses the slip is essential. The effect of aging and plantar sensory loss on detection of a slip can also be studied. Using psychophysical procedures, acceleration detection thresholds of small lateral whole-body perturbations were measured for healthy young adults (HYA), healthy older

Samantha J Richerson; Scott M Morstatt; Kristopher K O'Neal; Gloria Patrick; Charles J Robinson

2006-01-01

487

7. Historic American Buildings Survey Photocopy, August 1951 LATERAL VIEW, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. Historic American Buildings Survey Photocopy, August 1951 LATERAL VIEW, EAST FRONT, OLD PHOTOGRAPH c. 1850 Restricted: Permission for use must be obtained in writing from Art Library, Yale University, New Haven, Conn. - Skinner-Trowbridge House, 46 Hillhouse Avenue, New Haven, New Haven County, CT

488

12. SOUTHWEST VIEW OF FIRST CENTRE FAMILY DWELLING HOUSE, LATER ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

12. SOUTHWEST VIEW OF FIRST CENTRE FAMILY DWELLING HOUSE, LATER FARMER DEACON'S SHOP, WITH SECOND CENTRE FAMILY DWELLING HOUSE IN BACKGROUND - Shaker Centre Family Dwelling House (First), North side of Village Road, North of U.S. Route 68 & State Route 33 intersection, Shakertown, Mercer County, KY

489

Theoretical Study of the Cyclic Shakedown of Laterally Loaded Piles.  

National Technical Information Service (NTIS)

The paper describes a method for examining the theoretical response of single vertical piles to cyclic lateral load. The soil-pile interaction model is bilinear-elastoplastic and is based on subgrade reaction theory. The model allows the effects of soil y...

I. C. Swane H. G. Poulos

1982-01-01

490

The Lateral Somitic Frontier in Ontogeny and Phylogeny*  

PubMed Central

The vertebrate musculoskeletal system comprises the axial and appendicular systems. The postcranial axial system consists of the vertebrae, ribs and associated muscles, and the appendicular system comprises the muscles and skeleton of the paired appendages and their respective girdles. The morphology, proportions, and arrangements of these parts have undergone tremendous variation during vertebrate history. Despite this vertebrate diversity, the cells that form all of the key parts of the musculoskeletal system during development arise from two populations of embryonic mesoderm, the somites and somatic lateral plate. Nowicki et al. (2003. Mech Dev 120:227–240) identified two dynamic domains in the developing chick embryo. The primaxial domain is populated exclusively by cells from the somites. The abaxial domain includes muscle and bone that develop within lateral plate-derived connective tissue. The boundary between the two domains is the lateral somitic frontier. We hypothesize that the primaxial and abaxial domains are patterned independently and that morphological evolution of the musculoskeletal system is facilitated by partially independent developmental changes in the abaxial and primaxial domain. Here we present our hypothesis in detail and review recent experimental and comparative studies that use the concept of the lateral somitic frontier in the analysis of the evolution of the highly derived chelonian and limbless squamate body plans.

SHEARMAN, REBECCA MARIE; BURKE, ANN CAMPBELL

2010-01-01

491

A Longitudinal Study of the Development of Dichhaptic Lateralization.  

ERIC Educational Resources Information Center

|A follow-up study was made of cross-sectional research on the development of dichhaptic lateralization. One hundred and eighty students in grades 3, 5, 7, 9, and 11 from two school districts were tested. Participants were 9 boys and 9 girls from each grade level for each district. Subjects were at least 90 percent right-handed, as determined by…

Van Blerkom, Malcolm L.

492

Lateral epicondylitis: a review of pathology and management.  

PubMed

Lateral epicondylitis, or 'tennis elbow', is a common condition that usually affects patients between 35 and 55 years of age. It is generally self-limiting, but in some patients it may continue to cause persistent symptoms, which can be refractory to treatment. This review discusses the mechanism of disease, symptoms and signs, investigations, current management protocols and potential new treatments. PMID:23997125

Ahmad, Z; Siddiqui, N; Malik, S S; Abdus-Samee, M; Tytherleigh-Strong, G; Rushton, N

2013-09-01

493

Feeding preterm infants today for later metabolic and cardiovascular outcomes.  

PubMed

Preterm birth continues to contribute disproportionately to neonatal morbidity and subsequent physical and neurodevelopmental disabilities. Epidemiologic studies have described additional long-term health consequences of preterm birth such as an increased risk of hypertension and insulin resistance in adult life. It is not known whether the influence of infant and childhood growth rates and early nutrition on long-term outcomes is the same or different among preterm infants and neonates with intrauterine growth restriction. Our goal is to review the effects of fetal growth, postnatal growth, and early nutrition on long-term cardiovascular and metabolic outcomes in preterm infants. Present evidence suggests that even brief periods of relative undernutrition during a sensitive period of development have significant adverse effects on later development. Our review suggests that growth between birth and expected term and 12-18 months post-term has no significant effect on later blood pressure and metabolic syndrome, whereas reduced growth during hospitalization significantly impacts later neurodevelopment. In contrast, growth during late infancy and childhood appears to be a major determinant of later metabolic and cardiovascular well being, which suggests that nutritional interventions during this period are worthy of more study. Our review also highlights the paucity of well-designed, controlled studies in preterm infants of the effects of nutrition during hospitalization and after discharge on development, the risk of developing hypertension, or insulin resistance. PMID:23445851

Lapillonne, Alexandre; Griffin, Ian J

2013-03-01