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1

Influência da utilização da órtese de tornozelo durante atividades do voleibol: avaliação eletromiográfica  

Microsoft Academic Search

RESUMO Entorse de tornozelo é a lesão aguda mais freqüentemente en- contrada no voleibol. Com o intuito de prevenir a ocorrência de lesões de tornozelos, foram desenvolvidos equipamentos profilá- ticos, como as órteses. O objetivo deste estudo foi avaliar o de- sempenho dos músculos do tornozelo (tibial anterior, fibular longo e gastrocnêmio - porção medial e lateral) por meio da

Jefferson Rosa Cardoso; Christiane de Souza Macedo Guerino; Marcelo Bannwart Santos; Thiago André Del Arco Mustafá; Anália Rosário Lopes; Marcelo Costa de Paula

2005-01-01

2

Will Durant Foundation  

NSDL National Science Digital Library

While Will Durant is most well-known for his massive 11 volume Story of Civilization, the Will Durant Foundation Web site tells visitors about some of his other projects and life achievements, along with those of his wife, Ariel Durant. The site begins with a short essay offering a brief synopsis of Durant's life, including his relationship with his wife and the publishing icons Dick Simon and Max Schuster. The site contains articles written by Will Durant on a variety of subjects ranging from ancient Greece to the nature of civilization. For those interested in asking questions about Durant and his work, there is also an open and moderated discussion forum, along with a place for interested visitors to purchase any number of volumes authored by Mr. Durant and his wife.

2001-01-01

3

Prevendo a atividade solar através de redes neurais nebulosas  

NASA Astrophysics Data System (ADS)

Atualmente, a integração de redes neurais com técnicas da Matemática Nebulosa (Fuzzy Sets), tem sido usada robustamente para fazer previsões em vários sistemas físicos. Este trabalho representa uma continuidade da contribuição apresentada anteriormente durante a XXVIIa Reunião Anual da SAB, onde exploramos a aplicação de redes neurais para previsões futuras de séries temporais. Para este, enfatizamos o uso da técnica ANFIS (Adaptative Neuro-Fuzzy Inference System), que consiste em uma rede do tipo back-propagation, onde os dados são processados em uma camada intermediária, tendo numa camada de saída, os dados numéricos. Para que a previsão seja feita com sucesso utilizando-se técnicas matemáticas adequadas, é fundamental a existência de uma série razoavelmente longa de modo que a dinâmica contida nesta possa ser melhor extraída pela rede neural. Nesse sentido, foram utilizados novamente os dados históricos das manchas do Sol (1818-2002) afim de verificar o comportamento futuro da atividade solar (Ciclos de Schawbe) a partir da técnica descrita acima. Previsões realizadas para o ciclo anterior (n.22, máximo de 158,5 em julho de 1989), bem como para o atual (n.23, máximo de 153 em setembro de 2000), apontam valores bastante coerentes com os publicados na literatura, levando em consideração, respectivamente, as barras de erros associadas: 166+/-18 e 160+/-14. Para o próximo ciclo de Schawbe (2006-2017), nossa previsão aponta o valor de 172+/-23 como máximo para o primeiro semestre de 2011 (Abril +/- 3 meses). A ANFIS acompanha de maneira satisfatória o movimento das séries estudadas durante o treinamento e durante a verificação (menor dispersão das funções de pertinência), com erro absoluto inferior a 20 por cento.

Martin, V. A. F.; Poppe, P. C. R.

2003-08-01

4

Cuidados paliativos durante el cáncer  

Cancer.gov

Hoja informativa que describe la función de los cuidados paliativos, los cuales son los cuidados que se brindan a pacientes que tienen una enfermedad grave o potencialmente letal, como el cáncer, desde el momento del diagnóstico y durante todo el curso de la enfermedad.

5

Lateral orientation (image)  

MedlinePLUS

A lateral orientation is a position away from the midline of the body. For instance, the arms are lateral to the ... ears are lateral to the head. A medial orientation is a position toward the midline of the ...

6

Lateral collateral ligament (image)  

MedlinePLUS

The lateral collateral ligament connects the end of the femur (thigh) to the top of the fibula (the thin ... that runs next to the shin bone). The lateral collateral ligament provides stability against varus stress. Varus ...

7

Lateral plantar neuropathy.  

PubMed

We report 8 cases of lateral plantar neuropathy (LPN). All had sensory impairment over the territory of the lateral plantar nerve. Near-nerve needle sensory nerve conduction study (NCS) of the plantar nerves showed abnormality confined to the lateral plantar nerve, confirming LPN. The most common cause for LPN was trauma and the most common site of injury was at the passage of the lateral plantar nerve through the abductor tunnel at the instep of the foot. PMID:10454719

Oh, S J; Kwon, K H; Hah, J S; Kim, D E; Demirci, M

1999-09-01

8

Lateral flow strip assay  

DOEpatents

A lateral flow strip assay apparatus comprising a housing; a lateral flow strip in the housing, the lateral flow strip having a receiving portion; a sample collection unit; and a reagent reservoir. Saliva and/or buccal cells are collected from an individual using the sample collection unit. The sample collection unit is immersed in the reagent reservoir. The tip of the lateral flow strip is immersed in the reservoir and the reagent/sample mixture wicks up into the lateral flow strip to perform the assay.

Miles, Robin R. (Danville, CA); Benett, William J. (Livermore, CA); Coleman, Matthew A. (Oakland, CA); Pearson, Francesca S. (Livermore, CA); Nasarabadi, Shanavaz L. (Livermore, CA)

2011-03-08

9

Primary Lateral Sclerosis  

MedlinePLUS

... When symptoms begin, PLS may be mistaken for amyotrophic lateral sclerosis (ALS) or spastic paraplegia. Most neurologists follow an affected ... 1-877-773-4483) Fax: 877-SPF-GIVE ALS Association 1275 K Street, N.W. Suite 1050 ...

10

Amyotrophic Lateral Sclerosis  

MedlinePLUS

Amyotrophic lateral sclerosis (ALS) is a nervous system disease that attacks nerve cells called neurons in your brain and spinal cord. These neurons ... breathing machine can help, but most people with ALS die from respiratory failure. The disease usually strikes ...

11

Laterally bendable belt conveyor  

DOEpatents

An endless, laterally flexible and bendable belt conveyor particularly adapted for coal mining applications in facilitating the transport of the extracted coal up- or downslope and around corners in a continuous manner is disclosed. The conveying means includes a flat rubber belt reinforced along the middle portion thereof along which the major portion of the belt tension is directed so as to cause rotation of the tubular shaped belt when trammed around lateral turns thus preventing excessive belt bulging distortion between adjacent belt supports which would inhibit belt transport. Pretension induced into the fabric reinforced flat rubber belt by conventional belt take-up means supports the load conveyed when the belt conveyor is making lateral turns. The carrying and return portions of the belt are supported and formed into a tubular shape by a plurality of shapers positioned along its length. Each shaper is supported from above by a monorail and includes clusters of idler rollers which support the belt. Additional cluster rollers in each shaper permit the belt supporting roller clusters to rotate in response to the belt's operating tension imposed upon the cluster rollers by induced lateral belt friction forces. The freely rotating roller clusters thus permit the belt to twist on lateral curves without damage to itself while precluding escape of the conveyed material by effectively enclosing it in the tube-shaped, inner belt transport length.

Peterson, William J. (Coraopolis, PA)

1985-01-01

12

Les succédanés du sucre durant la grossesse  

PubMed Central

Résumé Question J’ai une patiente enceinte qui consomme souvent des succédanés du sucre et elle m’a demandé si cette pratique continue pouvait nuire à sa grossesse ou à son enfant. Que devrais-je lui répondre et existe-t-il d’autres meilleurs choix durant la grossesse? Réponse Il faudrait faire plus de recherche pour déterminer plus exactement les effets de l’exposition aux succédanés du sucre in utero, mais les données disponibles ne laissent pas présager d’effets indésirables durant la grossesse. Toutefois, il est recommandé de consommer des substituts du sucre en quantités modérées et de se conformer aux doses journalières admissibles établies par les organismes de règlementation.

Pope, Eliza; Koren, Gideon; Bozzo, Pina

2014-01-01

13

Bilateral lateral periodontal cyst.  

PubMed

The bilateral lateral periodontal cyst is a rare nasological entity, which despite clinical and radiological presentation is being diagnosed by histological characteristics. It is asymptomatic in nature and is observed in routine radiography. The aim and objective of this article is to present a rare case of bilateral lateral periodontal cyst in a 14-year-old child. The clinical and radiographical findings, along with its management have been discussed. Enucleation of bilateral cyst without extraction of the adjacent tooth was performed. Lesion samples were sent for histopathological analysis. The histopathological analysis revealed a thin, non keratinised stratified squamous epithelium resembling reduced enamel epithelium. Epithelial plaques were also seen. A clinicopathological correlation incorporating the surgical, radiographical and gold standard histopathological findings was obtained to suggest the final diagnosis of the bilateral lateral periodontal cyst. PMID:23667246

Govil, Somya; Gupta, Vishesh; Misra, Neeta; Misra, Pradyumna

2013-01-01

14

[Adult lateral meniscus].  

PubMed

Meniscal lesion does not mean meniscectomy and this is particularly true for the lateral meniscus. The reputation of mildness of the meniscectomy is usurped. The rate of joint space narrowing after lateral meniscectomy is of 40% at a follow-up of 13 years compared to 28% for the medial meniscus (symposium SFA 1996). Several arguments explain those results: biomechanical: the lateral meniscus contributes to the congruence; particularly the lateral meniscus is the zone where antero-posterior translational during knee flexion is 12 mm. The pejorative effects of lateral meniscectomy have conducted, more though to the medial meniscus, to the concept of meniscal economy. Lateral meniscectomy must be as partial as possible. Particularly, a discoid meniscus presenting a complete tear should be treated by a meniscoplasty in order to shape the meniscus in a more anatomic form than a total meniscectomy. Lateral meniscectomy is indicated in complex or horizontal cleavage, symptomatic, on stable knees. A particular case is the cyst of the lateral meniscus. It is a cystic subcutaneous formation, usual consequence of a horizontal cleaved meniscus of which the particularity is that it opens besides the articulation. The strategy must not consist in the isolated treatment of the cyst. This pathology should be addressed by an arthroscopic meniscectomy reaching the meniscosynovial junction at the level of the cyst. Meniscal repair must be proposed every time if possible. Criteria of reparability are better studied on MRI. Preoperatively MRI is the first choice radiological exam. Two essential indications can be held back: the vertical peripheral longitudinal lesion is on the non-vascularized area, and the horizontal cleaving of the junior athlete (if the cleaving remains purely intra meniscal). Meniscal repair is highly performed when the meniscal tear is associated to a rupture of the ACL (simultaneous reconstruction of the LCA). Postoperative outcome is different of that of a "simple" arthroscopic meniscectomy. The healing process being slow, it suits to protect the suture by a splint in the first month, and with an exclusion of sports with knee torsion during 6 months. Functional results (absence of secondary meniscectomy) and anatomical results (reality of the cicatrisation) are good in 77% of cases (symposium of the French Society of Arthroscopy 2003) at a follow-up of 55 months. Survivorship analysis indicates that majority of the failures occur within two years: this testifies a default of primary cicatrisation. At the studied follow-up, meniscal repair was efficient to protect the cartilage. Lateral meniscus results are better that medial meniscus one. Those data support indications: All suspicion of meniscal lesion must have an MRI preoperatively to confirm the lesion, to localize her and to search criteria of reparability; All vertical longitudinal peripheral lesions can and must be repaired especially in young patients and children; All horizontal cleaving of the junior athletes should be treated by open repair; surgical abstention must be proposed when the lesion is non symptomatic, or when lesion is limited and associated to an ACL tear (in that case isolated ACL reconstruction is proposed), or when clinical symptoms are minimal; Meniscectomy, always arthroscopic, is proposed for a symptomatic lesion in the avascular zone or for a deep horizontal cleavage or a complex tear; Tear of the discoid meniscus should be treated by meniscoplasty. A painful knee after lateral meniscectomy might be due to a too limited initial meniscectomy: an iterative meniscectomy may be indicated or lateral femorotibial arthritis, especially after subtotal or total meniscectomy. In this last case and after failure of usual medical treatment such as viscosupplementation surgery may be indicated. Osteotomy in order to unload the lateral femorotibial compartment gives a partial response as the shearing forces remain. This osteotomy is indicated only if the lower limb axis is normal or in valgus. Meniscal allograft is an option in young patients

Beaufils, P; Hardy, P; Chambat, P; Clavert, P; Djian, P; Frank, A; Hulet, C; Potel, J-F; Verdonk, R

2006-09-01

15

Delete It Later  

NSDL National Science Digital Library

Have you ever wanted to delete a Facebook or Twitter post after it was published? It can be a good practice but can be tough to remember. Delete It Later allows users to schedule the posting of statuses, updates, and photos along with the option to schedule when the content will be removed. This version is compatible with all operating systems.

2014-05-22

16

[Amyotrophic lateral sclerosis].  

PubMed

Amyotrophic lateral sclerosis (ALS) is an aggressive degeneration of upper and lower motor neurons and thus affects both the central and the peripheral nervous system. Clinically, the disease is characterized by rapidly progressing atrophy and paresis of all muscle groups with a letal outcome after three to six years due to paresis of the respiratory muscles. So far, no causal treatment is known. PMID:25632606

Hübers, Annemarie; Weishaupt, Jochen H; Ludolph, Albert C

2014-10-01

17

Amyotrophic lateral sclerosis.  

PubMed

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder affecting 20,000 to 30,000 people in the United States. The mainstay of care of patients affected by this disease is supportive and given the multifaceted nature of their needs is provided most efficiently through multidisciplinary clinics that have shown to prolong survival and improve quality of life. The authors discuss in detail evidence-based management of individuals affected by this condition. PMID:25520025

Malik, Rabia; Lui, Andrew; Lomen-Hoerth, Catherine

2014-11-01

18

Lateral transperitoneal laparoscopic adrenalectomy  

Microsoft Academic Search

Several laparoscopic approaches to the adrenal gland have been described. The lateral transperitoneal approach has several\\u000a distinct advantages when contrasted with other techniques for laparoscopic adrenalectomy (LA). We present our technique and\\u000a results obtained in 50 consecutive transperitoneal LAs. We review 50 consecutive laparoscopic adrenalectomies (28 female,\\u000a 19 male) performed from 1993 to 1998. S.J. Shichman or R.E. Sosa was

Steven J. Shichman; C. D. Anthony Herndon; R. Ernest Sosa; Giles F. Whalen; Dougald C. MacGillivray; Carl D. Malchoff; E. Darracott Vaughan

1999-01-01

19

Start School Later  

NSDL National Science Digital Library

Last month, Pediatrics, the official journal of the American Academy of Pediatrics (AAP), issued a formal policy statement concerning School Start Times for Adolescents (http://pediatrics.aappublications.org/content/early/2014/08/19/peds.2014-1697.abstract?sid=3f739b0e-a552-4a4a-bd0a-907809e20255). In essence, the AAP called for schools to start later, citing sleep deprivation among teenagers as â??an important public health issue.â? This site from Start School Later, a group advocating for â??health, safety and equity in education,â? provides good, if somewhat one-sided, information on the topic. If youâ??re unfamiliar, start with Research & Info, which provides links to a number of informative sites about adolescent sleep needs and the impact of early school start times. Success Stories takes readers to schools around the country that have experimented with, and benefited from, later start times. If you're inspired, you can also Get Involved. Whatever your position on the issue, this is an informative and interesting site.

20

Lateral periodontal cyst.  

PubMed

The lateral periodontal cyst (LPC) is a harmless developmental aberration derived from odontogenic epithelia lying between the roots of vital teeth. The exact histogenesis of LPC is a matter of debate but therapy is usually only required to maintain stable periodontal conditions and in case of evidence for growth of the cyst. We report on a case of LPC where successful surgical therapy had initialized osseous restoration. We further discuss the value of histological findings to substantiate a clinical and radiological diagnosis. PMID:24982228

Friedrich, Reinhard E; Scheuer, Hanna A; Zustin, Jozef

2014-01-01

21

Amyotrophic Lateral Sclerosis (ALS)  

NSDL National Science Digital Library

This patient education program explains amyotrophic lateral sclerosis (ALS or Lou Gehrig's Disease) including the causes, symptoms, diagnosis and treatment options. This resource is a MedlinePlus Interactive Health Tutorial from the National Library of Medicine, designed and developed by the Patient Education Institute. NOTE: This tutorial requires a special Flash plug-in, version 4 or above. If you do not have Flash, you will be prompted to obtain a free download of the software before you start the tutorial. You will also need an Acrobat Reader, available as a free download, in order to view the Reference Summary.

Patient Education Institute

22

Lateral conduction infrared photodetector  

DOEpatents

A photodetector for detecting infrared light in a wavelength range of 3-25 .mu.m is disclosed. The photodetector has a mesa structure formed from semiconductor layers which include a type-II superlattice formed of alternating layers of InAs and In.sub.xGa.sub.1-xSb with 0.ltoreq.x.ltoreq.0.5. Impurity doped regions are formed on sidewalls of the mesa structure to provide for a lateral conduction of photo-generated carriers which can provide an increased carrier mobility and a reduced surface recombination. An optional bias electrode can be used in the photodetector to control and vary a cut-off wavelength or a depletion width therein. The photodetector can be formed as a single-color or multi-color device, and can also be used to form a focal plane array which is compatible with conventional read-out integrated circuits.

Kim, Jin K. (Albuquerque, NM); Carroll, Malcolm S. (Albuquerque, NM)

2011-09-20

23

Breve panorama del teatro en Ecuador durante los años 80  

E-print Network

forma regular su actividad durante los años setenta, algunos como el Teatro Ensayo, en Quito, han desaparecido. Otros han sido creados y luchan por establecerse y por sostener una acción continua. Durante los ochenta se continuó la labor de amplia..., en la cual resaltaron sus cualidades de expresión corporal y mímica. Este montaje obtuvo buena acogida en festivales de Colombia, Uruguay y Brasil. También durante 1986 se presentó El inmigrante dirigido e interpretado por Carlos Michelena, actor...

Almeida Naveda, Eduardo

1992-04-01

24

Laterally oscillating nitinol engine  

SciTech Connect

This patent describes a laterally oscillating nitinol engine comprising: a first L-shaped drive member journalled for pivoting horizontal oscillation about the juncture of the legs of the L-shaped member, a second drive member journalled for pivoting about a point proximate the outboard end of the shorter leg of the L-shaped member at a distance from the pivot journal of the L-shaped member, a bearing block secured to the end of longer leg of the L-shaped and having a guide hole. The second member extending through the guide hole and arranged to reciprocate therein, a shape memory alloy power element disposed in flexure secured at its ends to the bearing block and to the second member intermediate the sliding connection with the bearing block and the pivotal connection of the second member, means for disposing different temperature baths below the element whereby as the drive members oscillate about their journals the element alternately dips into one bath and then the other, and means for absorbing a portion of the energy developed by the engine and moving the power element from the cold bath to the hot bath.

Banks, R.

1987-09-08

25

Reflexive Planning for Later Life  

Microsoft Academic Search

Informed by Giddens’ (1991) concept of reflexive life planning and the notion of later life as a time of increasing social and financial risk, this research explores the idea of reflexive planning for later life. We utilize a conceptual model that incorporates three types of planning for later life: public protection, self-insurance, and self-protection. Drawing on qualitative, life-history data from

Margaret A. Denton; Candace L. Kemp; Susan French; Amiram Gafni; Anju Joshi; Carolyn J. Rosenthal; Sharon Davies

2004-01-01

26

Amyotrophic lateral sclerosis  

PubMed Central

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterised by progressive muscular paralysis reflecting degeneration of motor neurones in the primary motor cortex, corticospinal tracts, brainstem and spinal cord. Incidence (average 1.89 per 100,000/year) and prevalence (average 5.2 per100,000) are relatively uniform in Western countries, although foci of higher frequency occur in the Western Pacific. The mean age of onset for sporadic ALS is about 60 years. Overall, there is a slight male prevalence (M:F ratio~1.5:1). Approximately two thirds of patients with typical ALS have a spinal form of the disease (limb onset) and present with symptoms related to focal muscle weakness and wasting, where the symptoms may start either distally or proximally in the upper and lower limbs. Gradually, spasticity may develop in the weakened atrophic limbs, affecting manual dexterity and gait. Patients with bulbar onset ALS usually present with dysarthria and dysphagia for solid or liquids, and limbs symptoms can develop almost simultaneously with bulbar symptoms, and in the vast majority of cases will occur within 1–2 years. Paralysis is progressive and leads to death due to respiratory failure within 2–3 years for bulbar onset cases and 3–5 years for limb onset ALS cases. Most ALS cases are sporadic but 5–10% of cases are familial, and of these 20% have a mutation of the SOD1 gene and about 2–5% have mutations of the TARDBP (TDP-43) gene. Two percent of apparently sporadic patients have SOD1 mutations, and TARDBP mutations also occur in sporadic cases. The diagnosis is based on clinical history, examination, electromyography, and exclusion of 'ALS-mimics' (e.g. cervical spondylotic myelopathies, multifocal motor neuropathy, Kennedy's disease) by appropriate investigations. The pathological hallmarks comprise loss of motor neurones with intraneuronal ubiquitin-immunoreactive inclusions in upper motor neurones and TDP-43 immunoreactive inclusions in degenerating lower motor neurones. Signs of upper motor neurone and lower motor neurone damage not explained by any other disease process are suggestive of ALS. The management of ALS is supportive, palliative, and multidisciplinary. Non-invasive ventilation prolongs survival and improves quality of life. Riluzole is the only drug that has been shown to extend survival. PMID:19192301

Wijesekera, Lokesh C; Leigh, P Nigel

2009-01-01

27

Sistema integrado de avaliação de impacto ambiental aplicado a atividades do Novo Rural  

Microsoft Academic Search

(2) Resumo - O objetivo deste trabalho foi apresentar o sistema de Avaliação Ponderada de Impacto Ambiental de Atividades do Novo Rural (APOIA-NovoRural), que consiste de um conjunto de planilhas eletrônicas (plataforma MS-Excel) que integram 62 indicadores da performance ambiental de uma atividade econômica em um estabelecimento rural. Cinco dimensões de avaliação foram consideradas: ecologia da paisagem, qualidade ambiental (atmosfera,

Geraldo Stachetti Rodrigues; Clayton Campanhola

2003-01-01

28

Lateral Thinking and Technology Education  

Microsoft Academic Search

The emergence of lateral thinking in recent years is a natural reaction to the enormous increase of information a human being is “bombarded” with, in the post industrial revolution era. Vertical thinking, with its sequential and fixed-order rules, which has been the foundation of traditional education, is increasingly being complemented by lateral thinking which aims at freeing the mind from

Shlomo Waks

1997-01-01

29

4, 317348, 2007 Lateral carbon  

E-print Network

BGD 4, 317­348, 2007 Lateral carbon exchange in a tidal mangrove creek S. Bouillon et al. Title mangrove creek (Ras Dege, Tanzania) S. Bouillon 1,2 , J. J. Middelburg 2 , F. Dehairs 1 , A. V. Borges 3, France 317 #12;BGD 4, 317­348, 2007 Lateral carbon exchange in a tidal mangrove creek S. Bouillon et al

Boyer, Edmond

30

CONSERVE SU SALUD DURANTE UN DESASTRE Alimentos y agua  

E-print Network

CONSERVE SU SALUD DURANTE UN DESASTRE Alimentos y agua Las situaciones de emergencia pueden afectar dientes ni las toallas. Al toser o estornudar, cubrase la boca con la parte superior del brazo o el codo

31

Lateral Transorbital Neuroendoscopic Approach to the Lateral Cavernous Sinus  

PubMed Central

Objective?To design and assess the quality of a novel lateral retrocanthal endoscopic approach to the lateral cavernous sinus. Design?Computer modeling software was used to optimize the geometry of the surgical pathway, which was confirmed on cadaver specimens. We calculated trajectories and surgically accessible areas to the middle fossa while applying a constraint on the amount of soft tissue retraction. Setting?Virtual computer model to simulate the surgical approach and cadaver laboratory. Participants?The authors. Main Outcome Measures?Adequate surgical access to the lateral cavernous sinus and adjacent regions as determined by operations on the cadaver specimens. Additionally, geometric limitations were imposed as determined by the model so that retraction on soft tissue structures was maintained at a clinically safe distance. Results?Our calculations revealed adequate access to the lateral cavernous sinus, Meckel cave, orbital apex, and middle fossa floor. Cadaveric testing revealed sufficient access to these areas using <10?mm of orbital retraction. Conclusions?Our study validates not only the use of computer simulation to plan operative approaches but the feasibility of the lateral retrocanthal approach to the lateral cavernous sinus. PMID:24498584

Bly, Randall A.; Ramakrishna, Rohan; Ferreira, Manuel; Moe, Kris S.

2013-01-01

32

SEXO DURANTE EL EMBARAZO viernes, 25 de enero de 2008  

E-print Network

SEXO DURANTE EL EMBARAZO Sexología viernes, 25 de enero de 2008 P: Primero que nada, muchas gracias, incluidos los médicos, me dicen que tener sexo en esta etapa es bueno, que es saludable, pero ¡wow!, no sé, su médico le puede aconsejar que limite o evite el sexo durante el embarazo si tiene: · antecedentes

Quirk, Gregory J.

33

Practical Astronomical Activities during Daytime. (Spanish Title: Actividades Astronómicas Prácticas Diurnas.) Atividades Astronômicas Práticas Diurnas  

NASA Astrophysics Data System (ADS)

These daytime astronomy activities arose from research done in New Zealand by a group of teachers and astronomers into the problems of teaching astronomy. This showed that it was generally regarded as a difficult subject to take, traditionally relying on books, films and models. The fortunate may have had a visit to an observatory or planetarium, the adventurous may have attempted an outdoor evening viewing session, which sometimes had weather-related difficulties. The problem of not having many 'hands-on' activities, the feelings of inadequate knowledge, the felt need for astronomical equipment and expertise become too daunting for many teachers to do the subject justice. If astronomy was to be taught then a way around these difficulties needed to be found. Our group, working with teachers and children using the constructivism teaching approach, found that the principles of astronomy could be discovered during the day when the students are at school. Working co-operatively they measured and recorded observations of their shadows caused by the motions and interactions of the nearest star, the Sun (Sol), and our planet, Earth. Because children were involved so personally they were much more interested in the results of the study. Astronomy became enthralling and challenging for both teacher and class after applying their daytime experiences to night time viewing at home and reporting back to class. Estas actividades astronómicas diurnas surgieron de una investigación hecha en NuevaZelandia por un grupo de maestros y astrónomos sobre los problemas de la enseñanza de la Astronomía. Este trabajo mostró que la Astronomía es generalmente considerada una disciplina difícil de enseñar, y tradicionalmente basada en libros, filmes y modelos. Los más afortunados pueden haber efectuado alguna visita a un observatorio o planetario, y los más aventajados pueden tal vez haber intentado una sesión de observación nocturna, las cuales sufren a veces de dificultades relacionadas al mal tiempo. El problema de no tener suficientes actividades prácticas, la sensación de poseer conocimientos inadecuados, la necesidad de disponer de equipamiento astronómico y experiencia suelen ser demasiado intimidantes para que los profesores introduzcan la materia en sus clases. Si la Astronomía iba a ser introducida, entonces era preciso encontrar una forma de resolver estas dificultades. Nuestro grupo, trabajando con maestros y alumnos dentro de un marco constructivista, encontró que los principios de la Astronomía pueden ser descubiertos durante el día, en cuanto los alumnos están en la escuela. Trabajando de forma cooperativa los alumnos midieron y registraron observaciones de sus propias sombras causadas por los movimientos de la estrella más próxima, el Sol, y nuestro planeta Tierra. Debido a que los alumnos se involucraran tan personalmente en las actividades, estuvieron mucho más interesados en los resultados del estudio. La Astronomía pasó a ser un desafío para el maestro y sus alumnos cuando aplicaron sus experiencias diurnas a la observación nocturna desde sus casas, reportada después en clase. Estas atividades astronômicas diurnas surgiram de uma investigação feita na Nova Zelândia por um grupo de professores e astrônomos a respeito dos problemas do ensino da Astronomia. Este trabalho mostrou que a Astronomia é geralmente considerada uma disciplina difícil de ensinar, tradicionalmente baseada em livros, filmes e modelos. Os mais afortunados podem ter feito alguma visita a um observatório ou planetário, e os mais avançados podem talvez ter tentado uma sessão de observação noturna, as quais sofrem às vezes de dificuldades relacionadas ao tempo. O problema de não dispor de suficientes atividades práticas, a sensação de possuir conhecimentos inadequados, a necessidade de dispor de equipamento astronômico e experiência tem sido, em geral, demasiado intimidante para que os professores introduzam a matéria nas suas aulas. Se a Astronomia ia ser introduzida, então era preciso encontrar uma forma de resol

Jackson, Eric

2009-12-01

34

Lateral collateral ligament (LCL) injury  

MedlinePLUS

LCL injury; Knee injury - lateral collateral ligament (LCL) ... ligament helps keep the outer side of the knee joint stable. ... by pressure or an injury that pushes the knee joint from the inside, which results in stress ...

35

Hyperaldosteronism: diagnosis, lateralization, and treatment.  

PubMed

Primary hyperaldosteronism is an important and commonly unrecognized secondary cause of hypertension. This article provides an overview of the current literature with respect to screening, diagnosis, and lateralization. Selection and outcomes of medical and surgical treatment are discussed. PMID:24857581

Harvey, Adrian M

2014-06-01

36

Bilateral Multiple Level Lateral Meningocoele  

PubMed Central

Lateral meningocoele is a very rare disorder characterized by extensions of the dura and arachnoid through an enlarged neural foramen. We report a case of a 23-year-old female with deformity of spine who presented with low back pain and no neurological deficits. A whole spine magnetic resonance imaging showed multiple well-defined cystic masses involving dorsal, lumbar, and sacral spinal levels bilaterally, with dural ectasia and neural foraminal widening suggestive of bilateral multiple level lateral meningocoele. The patient is being managed conservatively and is on regular follow-up. PMID:23607071

Kumar, B. E. Panil; Hegde, Kishor V.; Kumari, G. Lalitha; Agrawal, Amit

2013-01-01

37

Lateral Diffusion in an Archipelago  

PubMed Central

Lateral diffusion of molecules in lipid bilayer membranes can be hindered by the presence of impermeable domains of gel-phase lipid or of proteins. Effective-medium theory and percolation theory are used to evaluate the effective lateral diffusion constant as a function of the area fraction of fluid-phase lipid and the permeability of the obstructions to the diffusing species. Applications include the estimation of the minimum fraction of fluid lipid needed for bacterial growth, and the enhancement of diffusion-controlled reactions by the channeling effect of solid patches of lipid. PMID:7052153

Saxton, Michael J.

1982-01-01

38

Borehole optical lateral displacement sensor  

DOEpatents

There is provided by this invention an optical displacement sensor that utilizes a reflective target connected to a surface to be monitored to reflect light from a light source such that the reflected light is received by a photoelectric transducer. The electric signal from the photoelectric transducer is then imputed into electronic circuitry to generate an electronic image of the target. The target`s image is monitored to determine the quantity and direction of any lateral displacement in the target`s image which represents lateral displacement in the surface being monitored. 4 figs.

Lewis, R.E.

1998-10-20

39

Observation of lateral vehicle dynamics  

Microsoft Academic Search

By observation of lateral vehicle dynamics the detection of critical driving situations is made possible, as well as the estimation of adhesion characteristics during cornering. This paper presents a comparison of a linear and a nonlinear observer for the vehicle and tyre side-slip angles. The modelling, especially the model reduction and simplification, is shown.

U. Kiencke; A. Daiß

1997-01-01

40

Nuclear fuel rack lateral restraint  

Microsoft Academic Search

A lateral restraint device for nuclear fuel racks which can accommodate differential thermal expansion between the racks and a containing enclosure is described. The restraint includes a piston, movable within a cylinder, joined to one or more support pads which contact the wall of the enclosure. A spring is also provided within the cylinder to act upon the piston. The

D. J. Kaminski; C. H. Boyd

1979-01-01

41

Lateral Preferences in the Monkey  

Microsoft Academic Search

THERE is general agreement that the majority of monkeys show lateral preferences on a particular task1-6, about as many animals showing a strong preference for the left hand as for the right. However, Ettlinger5 reported that significantly more monkeys preferred to use the left hand than the right on their first discrimination task (irrespective of the task being visual or

G. Ettlinger; A. Moffett

1964-01-01

42

Lateral dampers for thrust bearings  

NASA Technical Reports Server (NTRS)

The development of lateral damping schemes for thrust bearings was examined, ranking their applicability to various engine classes, selecting the best concept for each engine class and performing an in-depth evaluation. Five major engine classes were considered: large transport, military, small general aviation, turboshaft, and non-manrated. Damper concepts developed for evaluation were: curved beam, constrained and unconstrained elastomer, hybrid boost bearing, hydraulic thrust piston, conical squeeze film, and rolling element thrust face.

Hibner, D. H.; Szafir, D. R.

1985-01-01

43

Detecting lateral genetic material transfer  

E-print Network

The bioinformatical methods to detect lateral gene transfer events are mainly based on functional coding DNA characteristics. In this paper, we propose the use of DNA traits not depending on protein coding requirements. We introduce several semilocal variables that depend on DNA primary sequence and that reflect thermodynamic as well as physico-chemical magnitudes that are able to tell apart the genome of different organisms. After combining these variables in a neural classificator, we obtain results whose power of resolution go as far as to detect the exchange of genomic material between bacteria that are phylogenetically close.

Calderón, C; Mireles, V; Miramontes, P

2012-01-01

44

Clinical Neurogenetics: Amyotrophic Lateral Sclerosis  

PubMed Central

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease, about which our understanding is expanding rapidly as its genetic causes are uncovered. The pace of new gene discovery over the last 5 years has accelerated, providing new insights into the pathogenesis of disease and highlighting biological pathways for target for therapeutic development. This article reviews our current understanding of the heritability of ALS, provides an overview of each of the major ALS genes, highlighting their phenotypic characteristics and frequencies as a guide for clinicians evaluating patients with ALS. PMID:24176417

Harms, Matthew B.; Baloh, Robert H.

2013-01-01

45

Lateral genetic transfer: open issues  

PubMed Central

Lateral genetic transfer (LGT) is an important adaptive force in evolution, contributing to metabolic, physiological and ecological innovation in most prokaryotes and some eukaryotes. Genomic sequences and other data have begun to illuminate the processes, mechanisms, quantitative extent and impact of LGT in diverse organisms, populations, taxa and environments; deep questions are being posed, and the provisional answers sometimes challenge existing paradigms. At the same time, there is an enhanced appreciation of the imperfections, biases and blind spots in the data and in analytical approaches. Here we identify and consider significant open questions concerning the role of LGT in genome evolution. PMID:19571244

Ragan, Mark A.; Beiko, Robert G.

2009-01-01

46

Lateralization of aggression in fish.  

PubMed

Recent research has suggested that lateralization of aggressive behaviors could follow an homogeneous pattern among all vertebrates. A left eye/right hemisphere dominance in eliciting aggressive responses has been demonstrated for all groups of tetrapods but teleost fish for which data is lacking. Here we studied differential eye use during aggressive interactions in three species of teleosts: Gambusia holbrooki, Xenotoca eiseni and Betta splendens. In the first experiment we checked for lateralization in the use of the eyes while the subject was attacking its own mirror image. In order to confirm the results, other tests were performed on two species and eye preference was scored during attacks or displays directed toward a live rival. All three species showed a marked preference for using the right eye when attacking a mirror image or a live rival. Thus, the direction of asymmetry in fish appears the opposite to that shown by all the other groups of vertebrates. Hypotheses on the origin of the difference are discussed. PMID:12742249

Bisazza, Angelo; de Santi, Andrea

2003-05-15

47

The Enduring Influence of Parent's Voluntary Involvement on Their Children's Volunteering in Later Life.  

PubMed

This study investigates the effect of parent's voluntary involvement on their children's volunteering in later life, and examines the degree to which this effect persists across older age cohorts. To accomplish this, we make use of retrospective questions from the 2010 Canada Survey of Giving, Volunteering and Participating that ask respondents about their experiences in their school-age years. The results show that parental voluntary involvement is positively related to adult voluntary participation, and that the effect of parental voluntary involvement on later volunteerism appears to persist well into adulthood. The implications of these findings for volunteering in Canada are discussed. Cette étude examine l'effet de la participation bénévole des parents sur le bénévolat de leurs enfants plus tard durante leur vie et la mesure dans laquelle cet effet persiste dans les cohortes plus âgées. À cette fin, nous faisons appel à des questions rétrospectives de l'Enquête canadienne sur le don, le bénévolat et la participation de 2010 qui pose aux répondants des questions sur leurs expériences durant leurs années d'âge scolaire. Les résultats montrent que la participation volontaire des parents est positivement liée à la participation volontaire des adultes et que l'effet de la participation bénévole des parents sur le bénévolat de leurs enfants plus tard dans leur vie semble persister durant leur âge adulte. Les implications de ces résultats pour le bénévolat au Canada sont discutées. PMID:25737466

Perks, Thomas A; Konecny, Daniel

2015-02-01

48

Managing Complications of Diabetes in Later Life  

MedlinePLUS

... Download PDF Managing Complications of Diabetes in Later Life Download Join our e-newsletter! Resources Managing Complications of Diabetes in Later Life Tools and Tips Printer-friendly PDF Click here ...

49

49 CFR 230.105 - Lateral motion.  

Code of Federal Regulations, 2010 CFR

...ADMINISTRATION, DEPARTMENT OF TRANSPORTATION STEAM LOCOMOTIVE INSPECTION AND MAINTENANCE STANDARDS Steam Locomotives and Tenders Running Gear § 230.105 Lateral motion. (a) Condemning limits. The total lateral motion or play between...

2010-10-01

50

Kepler: 400 years later Jonas Karlsson  

E-print Network

Kepler: 400 years later #12;Outline Kepler's laws Proof that closed orbits are ellipses The hydrogen atom Geodesic ow and the Kepler manifold Jonas Karlsson Kepler: 400 years later #12;Kepler's laws Johannes Kepler (1571 - 1630) Jonas Karlsson Kepler: 400 years later #12;Kepler's laws First law (1609

Weinberger, Hans

51

Auxin Transport Promotes Arabidopsis Lateral Root Initiation  

Microsoft Academic Search

Lateral root development in Arabidopsis provides a model for the study of hormonal signals that regulate postembry- onic organogenesis in higher plants. Lateral roots originate from pairs of pericycle cells, in several cell files positioned opposite the xylem pole, that initiate a series of asymmetric, transverse divisions. The auxin transport inhibitor N -1-naph- thylphthalamic acid (NPA) arrests lateral root development

Ilda Casimiro; Alan Marchant; Rishikesh P. Bhalerao; Tom Beeckman; Sandra Dhooge; Ranjan Swarup; Neil Graham; Dirk Inzé; Goran Sandberg; Pedro J. Casero; Malcolm Bennett

2001-01-01

52

49 CFR 229.63 - Lateral motion.  

Code of Federal Regulations, 2010 CFR

...2010-10-01 2010-10-01 false Lateral motion. 229.63 Section 229.63...Requirements Suspension System § 229.63 Lateral motion. (a) Except as provided in paragraph (b), the total uncontrolled lateral motion between the hubs of the...

2010-10-01

53

CYSTS OF THE LATERAL MENISCUS  

PubMed Central

Accurate diagnosis and management of knee pain with or without mechanical symptoms challenges the physical therapist's clinical reasoning skills. Meniscal cysts are one relatively rare disorder of the knee that can cause both pain and mechanical symptoms and are frequently associated with a meniscal tear. In patients with suspected meniscal cysts, systematic differential diagnosis and sound clinical reasoning encourages appropriate integration of the clinical examination with diagnostic imaging. These case reports describe two different presentations of lateral parameniscal cysts where integration of the clinical examination with appropriate imaging allowed the physical therapist to provide a timely and appropriate intervention. In both cases, the diagnostic process is described along with the subsequent interventions that lead to positive outcomes. Level of Evidence: 5 (Case Report) PMID:23772349

Westrick, Richard B.; Fogarty, Brian T.

2013-01-01

54

Biomarkers in amyotrophic lateral sclerosis.  

PubMed

Amyotrophic lateral sclerosis (ALS; motor neuron disease) is a relentlessly progressive disorder. After half a century of trials, only one drug with modest disease-modifying potency--riluzole--has been developed. The diagnosis of this disorder is still clinical and there is a pronounced delay between the onset of symptoms and diagnosis, possibly beyond the therapeutic window. Bedside quantification of the involvement of the corticospinal tract and extramotor areas is inadequate and functional rating scales, forced vital capacity, and patient survival have been the measures of therapeutic response so far. Potential biomarkers that are sensitive to the progression of disease, which might enhance the diagnostic algorithm and provide new drug targets, are now being identified from analysis of the blood and cerebrospinal fluid, as well as from neuroimaging and neurophysiology studies. In combination, these biomarkers might be sensitive to early therapeutic effects and would reduce our reliance on animal models, which have uncertain relevance to sporadic ALS in human beings. Such biomarkers might also resolve complexities of phenotypic heterogeneity in clinical trials. In this Review, we discuss the development of biomarkers in ALS and consider potential future directions for research. PMID:19081518

Turner, Martin R; Kiernan, Matthew C; Leigh, P Nigel; Talbot, Kevin

2009-01-01

55

Wilson's disease, 100 years later….  

PubMed

Texts published, in 1912, 100 years ago, by Sir K. Wilson on his eponymous disease in Brain, The Lancet and La Revue Neurologique highlight the relevance of his descriptions in the light of the current knowledge. Wilson's invocation of an "unknown toxin" appears today as a prophetic intuition as the presence of excess copper in the liver was mentioned for the first time a year later whereas the role of copper in this disease was not described until 1929. Progress has been made to better understand the physiology of Wilson's disease (WD). The ATP7B gene implicated in WD is located on chromosome 13 and more than 500 mutations and 100 polymorphisms have been to date identified. The phenotypic expression is highly variable, even within a family. This can partly be explained by environmental factors as nutrition. Modulator genes are also involved in the phenotypic expression of the disease. Most of symptoms observed in WD have already been described in detail by Wilson in 1912, but subsequent progress was made over the following 100 years, helping the physician diagnose WD. Hepatic and neurological symptoms are the most frequent expressions of the disease. Other extrahepatic features include renal manifestations, osteoarticular disorders, myocardial abnormalities, endocrine disturbances, realizing a multisystemic disease. The diagnosis of the disease is based on a combination of clinical symptoms, biological, radiological and genetic data and new tools (Brain MRI, relative exchangeable copper…) allow reducing delay to diagnosis. Therapeutic findings have also changed the disease prognosis. Treatment is based on the use of copper chelators to promote copper excretion from the body (D-penicillamine and Triethylenetetramine) and zinc salts to reduce copper absorption. Tetratiomolybdate appears to be a promising treatment. While significant progress has been made during this century, many physiological aspects of this disease remain unknown and require further research to find answers in the next 100 years. PMID:24119853

Trocello, J-M; Broussolle, E; Girardot-Tinant, N; Pelosse, M; Lachaux, A; Lloyd, C; Woimant, F

2013-12-01

56

Retroviruses and amyotrophic lateral sclerosis  

PubMed Central

Amyotrophic lateral sclerosis (ALS) is a progressive, invariably fatal neurologic disorder resulting from upper and lower motor neuron degeneration, which typically develops during the sixth or seventh decade of life, and is diagnosed based on standard clinical criteria. Its underlying cause remains undetermined. The disease may occur with increased frequency within certain families, often in association with specific genomic mutations, while some sporadic cases have been linked to environmental toxins or trauma. Another possibility, first proposed in the 1970s, is that retroviruses play a role in pathogenesis. In this paper, we review the published literature for evidence that ALS is associated either with infection by an exogenous retrovirus or with the expression of human endogenous retroviral (HERV) sequences in cells of the central nervous system. A small percentage of persons infected with the human immunodeficiency virus-1 (HIV-1) or human T cell leukemia virus-1 (HTLV-1) develop ALS-like syndromes. While HTLV-1 associated ALS-like syndrome has several features that may distinguish it from classical ALS, HIV-infected patients may develop neurological manifestations that resemble classical ALS although it occurs at a younger age and they may show a dramatic improvement following the initiation of antiretroviral therapy. However, most patients with probable or definite ALS show no evidence of HIV-1 or HTLV-1 infection. In contrast, recent reports have shown a stronger association with HERV, as analysis of serum samples, and postmortem brain tissue from a number of patients with a classical ALS has revealed significantly increased expression of HERV-K, compared to controls. These findings suggest that endogenous retroviral elements are involved in the pathophysiology of ALS, but there is no evidence that they are the primary cause of the syndrome. PMID:23707220

Alfahad, Tariq; Nath, Avindra

2013-01-01

57

Retroviruses and amyotrophic lateral sclerosis.  

PubMed

Amyotrophic lateral sclerosis (ALS) is a progressive, invariably fatal neurologic disorder resulting from upper and lower motor neuron degeneration, which typically develops during the sixth or seventh decade of life, and is diagnosed based on standard clinical criteria. Its underlying cause remains undetermined. The disease may occur with increased frequency within certain families, often in association with specific genomic mutations, while some sporadic cases have been linked to environmental toxins or trauma. Another possibility, first proposed in the 1970s, is that retroviruses play a role in pathogenesis. In this paper, we review the published literature for evidence that ALS is associated either with infection by an exogenous retrovirus or with the expression of human endogenous retroviral (HERV) sequences in cells of the central nervous system. A small percentage of persons infected with the human immunodeficiency virus-1 (HIV-1) or human T cell leukemia virus-1 (HTLV-1) develop ALS-like syndromes. While HTLV-1 associated ALS-like syndrome has several features that may distinguish it from classical ALS, HIV-infected patients may develop neurological manifestations that resemble classical ALS although it occurs at a younger age and they may show a dramatic improvement following the initiation of antiretroviral therapy. However, most patients with probable or definite ALS show no evidence of HIV-1 or HTLV-1 infection. In contrast, recent reports have shown a stronger association with HERV, as analysis of serum samples, and postmortem brain tissue from a number of patients with a classical ALS has revealed significantly increased expression of HERV-K, compared to controls. These findings suggest that endogenous retroviral elements are involved in the pathophysiology of ALS, but there is no evidence that they are the primary cause of the syndrome. PMID:23707220

Alfahad, Tariq; Nath, Avindra

2013-08-01

58

Artificial lateral line canal for hydrodynamic detection  

NASA Astrophysics Data System (ADS)

Fish use their lateral line system to detect minute water motions. The lateral line consists of superficial neuromasts and canal neuromasts. The response properties of canal neuromasts differ from those of superficial ones. Here, we report the design, fabrication, and characterization of an artificial lateral line canal system. The characterization was done under various fluid conditions, including dipolar excitation and turbulent flow. The experimental results with dipole excitation match well with a mathematical model. Canal sensors also demonstrate significantly better noise immunity compared with superficial ones. Canal-type artificial lateral lines may become important for underwater flow sensing.

Yang, Yingchen; Klein, Adrian; Bleckmann, Horst; Liu, Chang

2011-07-01

59

Simultaneous medial and lateral patellofemoral ligament reconstruction for combined medial and lateral patellar subluxation.  

PubMed

Medial patellar subluxation (MPS) is a disabling, often iatrogenic patellar instability due to previous lateral release for patellar instability. Lateral release destabilizes the patella on the lateral side, worsening the initial lateral instability and causing MPS. MPS is poorly recognized and may range from subluxation to true dislocation. This report describes a technique developed in response to episodes of medial and lateral patellar subluxation after failed lateral release for patellar instability. The technique uses a graft that extends from the medial patellofemoral ligament origin through the quadriceps tendon to the lateral epicondyle, thereby reconstructing both the medial and lateral patellofemoral ligaments, as well as providing simultaneous stability to both the medial and lateral sides of the patella. PMID:24904765

Saper, Michael G; Shneider, David A

2014-04-01

60

Lateral patellar retinaculum reconstruction for medial patellar instability following lateral retinacular release: a case report.  

PubMed

Lateral retinacular release is still being performed in patients with recurrent patellar dislocation as an additional procedure with distal realignment or medial patellofemoral ligament (MPFL) reconstruction. However, consensus remains lacking regarding suitable indications for lateral retinacular release. A 20-year-old woman presented with patellar instability in both medial and lateral directions after undergoing lateral retinacular release with MPFL reconstruction. She displayed inherent systemic joint laxity meeting all seven Carter-Wilkinson criteria. Simultaneous MPFL revision and lateral retinaculum reconstruction successfully improved patellar instability in both directions. This case provides an example of iatrogenic medial patellar instability after failed lateral retinacular release. PMID:23688523

Udagawa, Kazuhiko; Niki, Yasuo; Matsumoto, Hiroaki; Matsumoto, Hideo; Enomoto, Hiroyuki; Toyama, Yoshiaki; Suda, Yasunori

2014-01-01

61

Sobre a atividade pós-periélica do cometa de órbita parabólica Yanaka (1988r)  

NASA Astrophysics Data System (ADS)

Greenberg, Singh & de Almeida (ApJ, 414: L45-48, 1993) mostraram que a deficiência nas abundâncias observadas de C2 e CN no Cometa Yanaka (1988r) pode ser explicada em termos das propriedades dos seus componentes refratários orgânicos, além do fato que trata-se de um cometa dinamicamente novo, observado através de abertura de fenda pequena projetada muito próximo do núcleo. Neste trabalho, complementamos o estudo sobre a atividade deste cometa de órbita parabólica, através da determinação da lei de potência que exprime sua taxa de produção de H2O (o principal indicador de atividade) na fase pós-periélica, determinamos o raio nuclear efetivo mínimo com sua fração de área ativa e analisamos a emissão de partículas de poeira observadas no contínuo em 625,0 nm.

de Almeida, A. A.; Sanzovo, G. C.; Boczko, R.

2003-08-01

62

Usefulness of a Lateral Thoracodorsal Flap after Breast Conserving Surgery in Laterally Located Breast Cancer  

PubMed Central

Background Breast-conserving surgery is widely accepted as an appropriate method in breast cancer, and the lateral thoracodorsal flap provides a simple, reliable technique, especially when a mass is located in the lateral breast. This study describes the usefulness of a lateral thoracodorsal flap after breast conserving surgery in laterally located breast cancer. Methods From September 2008 to February 2013, a lateral thoracodorsal flap was used in 20 patients with laterally located breast cancer treated at our institution. The technique involves a local medially based, wedge shaped, fasciocutaneous transposition flap from the lateral region of the thoracic area. Overall satisfaction and aesthetic satisfaction surveys were conducted with the patients during a 6-month postoperative follow-up period. Aesthetic results in terms of breast shape and symmetry were evaluated by plastic surgeons. Results The average specimen weight was 76.8 g. The locations of the masses were the upper lateral quadrant (n=15), the lower lateral quadrant (n=2), and the central lateral area (n=3). Complications developed in four of the cases, partial flap necrosis in one, wound dehiscence in one, and fat necrosis in two. The majority of the patients were satisfied with their cosmetic outcomes. Conclusions Partial breast reconstruction using a lateral thoracodorsal flap is well matched with breast color and texture, and the surgery is less aggressive than other techniques with few complications. Therefore, the lateral thoracodorsal flap can be a useful, reliable technique in correcting breast deformity after breast conserving surgery, especially in laterally located breast cancer. PMID:23898433

Ryu, Dong Wan; Lee, Jeong Woo; Choi, Kang Young; Chung, Ho Yun; Cho, Byung Chae; Park, Ho Yong; Byun, Jin Suk

2013-01-01

63

Arthroscopic Centralization of an Extruded Lateral Meniscus  

PubMed Central

Extrusion of the lateral meniscus has been reported after posterior root tear or radial tear, partial meniscectomy, and meniscoplasty of discoid meniscus. It has also been shown to be associated with the development of osteoarthritis. This technical note describes a new arthroscopic technique to centralize and stabilize the mid body of the lateral meniscus to restore and maintain the lateral meniscus function by repairing/preventing extrusion of the meniscus. A JuggerKnot Soft Anchor (Biomet, Warsaw, IN), loaded with a MaxBraid suture (Biomet), was placed on the lateral edge of the lateral tibial plateau, just anterior to the popliteal hiatus, through a midlateral portal. A Micro Suture Lasso Small Curve with Nitinol Wire Loop (Arthrex, Naples, FL) was used to pass 2 limbs of the MaxBraid suture through the meniscus at the margin between the meniscus and the capsule. Another anchor was inserted on the lateral edge of the lateral tibial plateau, 1 cm anterior to the first anchor, and the same procedure was repeated. The sutures were then tied by use of a self-locking sliding knot, achieving centralization and secure stabilization of the lateral meniscus. PMID:23766997

Koga, Hideyuki; Muneta, Takeshi; Yagishita, Kazuyoshi; Watanabe, Toshifumi; Mochizuki, Tomoyuki; Horie, Masafumi; Nakamura, Tomomasa; Okawa, Atsushi; Sekiya, Ichiro

2012-01-01

64

Arthroscopic centralization of an extruded lateral meniscus.  

PubMed

Extrusion of the lateral meniscus has been reported after posterior root tear or radial tear, partial meniscectomy, and meniscoplasty of discoid meniscus. It has also been shown to be associated with the development of osteoarthritis. This technical note describes a new arthroscopic technique to centralize and stabilize the mid body of the lateral meniscus to restore and maintain the lateral meniscus function by repairing/preventing extrusion of the meniscus. A JuggerKnot Soft Anchor (Biomet, Warsaw, IN), loaded with a MaxBraid suture (Biomet), was placed on the lateral edge of the lateral tibial plateau, just anterior to the popliteal hiatus, through a midlateral portal. A Micro Suture Lasso Small Curve with Nitinol Wire Loop (Arthrex, Naples, FL) was used to pass 2 limbs of the MaxBraid suture through the meniscus at the margin between the meniscus and the capsule. Another anchor was inserted on the lateral edge of the lateral tibial plateau, 1 cm anterior to the first anchor, and the same procedure was repeated. The sutures were then tied by use of a self-locking sliding knot, achieving centralization and secure stabilization of the lateral meniscus. PMID:23766997

Koga, Hideyuki; Muneta, Takeshi; Yagishita, Kazuyoshi; Watanabe, Toshifumi; Mochizuki, Tomoyuki; Horie, Masafumi; Nakamura, Tomomasa; Okawa, Atsushi; Sekiya, Ichiro

2012-12-01

65

Lateral displacement and rotational displacement sensor  

DOEpatents

A position measuring sensor formed from opposing sets of capacitor plates measures both rotational displacement and lateral displacement from the changes in capacitances as overlapping areas of capacitors change. Capacitances are measured by a measuring circuit. The measured capacitances are provided to a calculating circuit that performs calculations to obtain angular and lateral displacement from the capacitances measured by the measuring circuit.

Duden, Thomas

2014-04-22

66

Monitoring System Design for Lateral Vehicle Motion  

Microsoft Academic Search

Monitoring of lateral vehicle motion is very useful in many active safety applications such as yaw stability control and rollover prevention. Lateral velocity and sideslip angle are regarded as the most important motion variables. However, it is not feasible during vehicle operation to directly measure them due to the high cost of sensors, limitations to sensor technology, etc. Therefore, the

Sangoh Han; Kunsoo Huh

2011-01-01

67

Anatomy of the Lateral Ankle Ligaments  

Microsoft Academic Search

The anatomy of the lateral ankle ligaments that is fre quently described in articles and book chapters often lacks the precision of orientation and attachment points. We believe a knowledge of this precise anatomy is im portant to better reconstruct or repair lateral ligaments. We dissected cadaveric ankles free of skin and soft tis sue and made the following measurements:

Robert T. Burks; James Morgan

1994-01-01

68

Later Life Social Engagement and Health  

Microsoft Academic Search

The topic of later life social engagement is of growing importance worldwide given the confluence of large demographic, economic, and sociocultural trends. However, empirical research in this area faces some serious theoretical and methodological limitations. The purpose of this study was to address these limitations by: (1) examining the later life mental and physical health effects of five social roles,

Manacy Pai

2008-01-01

69

Laterality and Dyslexia: A Critical View.  

ERIC Educational Resources Information Center

Research is reviewed concerning the current state of knowledge about normal hemispheric specialization; distinctions among such terms as dominance, laterality, and lateralization; and models of abnormal cerebral organization in dyslexic children. The question of dyslexic subtypes is undertaken along such dimensions as handedness, eyedness, and…

Hiscock, Merrill; Kinsbourne, Marcel

1982-01-01

70

Lateral transfer: a source of additional overpressure?  

Microsoft Academic Search

Overpressure generated by disequilibrium compaction can be enhanced at structural crests by the lateral transfer of fluids from deep, overpressured parts of a basin along laterally extensive inclined aquifers. Fluid flow modelling shows that the effect of an inclined aquifer ranges from being minimal to being a significant contributor (>10 MPa) to crestal pore pressures depending on the style of

G. S. Yardley; R. E. Swarbrick

2000-01-01

71

Aeromonas hydrophila Lateral Flagellar Gene Transcriptional Hierarchy  

PubMed Central

Aeromonas hydrophila AH-3 lateral flagella are not assembled when bacteria grow in liquid media; however, lateral flagellar genes are transcribed. Our results indicate that A. hydrophila lateral flagellar genes are transcribed at three levels (class I to III genes) and share some similarities with, but have many important differences from, genes of Vibrio parahaemolyticus. A. hydrophila lateral flagellum class I gene transcription is ?70 dependent, which is consistent with the fact that lateral flagellum is constitutively transcribed, in contrast to the characteristics of V. parahaemolyticus. The fact that multiple genes are included in class I highlights that lateral flagellar genes are less hierarchically transcribed than polar flagellum genes. The A. hydrophila lafK-fliEJL gene cluster (where the subscript L distinguishes genes for lateral flagella from those for polar flagella) is exclusively from class I and is in V. parahaemolyticus class I and II. Furthermore, the A. hydrophila flgAMNL cluster is not transcribed from the ?54/LafK-dependent promoter and does not contain class II genes. Here, we propose a gene transcriptional hierarchy for the A. hydrophila lateral flagella. PMID:23335410

Wilhelms, Markus; Gonzalez, Victor; Merino, Susana

2013-01-01

72

Pediatric laparoscopic splenectomy using the lateral approach  

Microsoft Academic Search

Laparoscopic splenectomy in children has been shown to be safe, to reduce postoperative pain and hospital stay, and to accelerate return to full activities. We describe our experience with a four-port “lateral” approach in 18 patients. Patients were placed in the lateral decubitus position and the table was flexed to separate the left subcostal margin and iliac crest. The camera

P. G. Fitzgerald; J. C. Langer; B. H. Cameron; A. E. Park; M. J. Marcaccio; J. M. Walton; M. A. Skinner

1996-01-01

73

[Lateral ligament injuries of the ankle joint].  

PubMed

Lateral ligament injuries are the most common sports injury and have a high incidence even in non-sportive activities. Although lateral ligament injuries are very common there is still a controversial debate on the best management. The diagnosis is based on clinical examination and X-ray images help to rule out fractures. Further imaging, especially magnetic resonance imaging (MRI) is used to diagnose associated injuries. According to the recommendations of the various scientific societies the primary therapy of lateral ligament injuries is conservative. Chronic ankle instability develops in 10-20 % of patients and the instability can be a result of sensomotoric deficits or insufficient healing of the lateral ligament complex. If the patient does not respond to an intensive rehabilitation program an operative reconstruction of the lateral ligaments has to be considered. Most of the procedures currently performed are anatomical reconstructions due to better long-term results compared to tenodesis procedures. PMID:23943058

Walther, M; Kriegelstein, S; Altenberger, S; Volkering, C; Röser, A; Wölfel, R

2013-09-01

74

A Proposed Activity for a Meaningful Learning about the Moon Phases. (Breton Title: Uma Proposta de Atividade Para a Aprendizagem Significativa sobre as Fases da Lua.) Una Actividad Propuesta Para EL Aprendizaje Significativo Acerca de Las Fases de la Luna  

NASA Astrophysics Data System (ADS)

This paper presents one of the concepts of Astronomy and its consequent failure in teaching this topic in high school, even when the official documents point out the necessity of Astronomy teaching at this school level. Among the spontaneous conceptions in Astronomy that high school students carry with them, even after the end of the school, we emphasized in this research the Moon phases. The development of different strategies in relation to traditional methods, aimed to teaching-learning process on this topic was considered in this study. These strategies were devised based on the reference frame of the Meaningful Learning, as elaborated by Ausubel. The proposals presented here include the active participation of students in experimental activities and other didactic activities, for their continuous evaluation during the process. These activities finished with a Comics elaboration about the Moon phases. Therefore, the objective of this paper is to present a proposal for differentiated teaching activity about Moon phases supported by the theoretical principles of Meaningful Learning at Physics classes. Este texto foca um dos conteúdos de Astronomia e a consequente falha no ensino deste tema no ensino médio, apesar de os documentos oficiais apresentarem a necessidade de se trabalhar a Astronomia neste nível de ensino. Dentre as concepções alternativas em Astronomia que os alunos do ensino médio carregam consigo, mesmo após o término dos estudos, destacamos, nesta pesquisa, o fenômeno das fases da Lua. O desenvolvimento de estratégias diferenciadas em relação ao ensino tradicional, visando o processo de ensino-aprendizagem sobre este tema, foi contemplado neste trabalho como um dos resultados obtidos sob a luz dos referenciais da aprendizagem significativa, fundamentados em Ausubel. Segundo a proposta aqui apresentada, a participação ativa dos alunos na execução de uma atividade experimental e outras atividades didáticas, que visam sua contínua avaliação durante o processo, culmina com a elaboração de uma história em quadrinhos envolvendo as fases da Lua. Portanto, o objetivo deste trabalho é apresentar uma proposta de atividade didática diferenciada sustentada pelos princípios teóricos da aprendizagem significativa aplicada ao ensino das fases da Lua durante as aulas de Física no ensino médio. En este trabajo se presenta uno de los contenidos de la Astronomía y el evidente fracaso en la enseñanza del tema en la escuela secundaria, a pesar del hecho que los documentos oficiales apuntan para la necesidad de trabajar contenidos de Astronomía en este nivel. Entre los conceptos alternativos en Astronomía que los alumnos secundarios llevan consigo, aún después de terminados los estudios, destacamos aquí el fenómeno de las fases de la Luna. El desarrollo de diferentes estrategias en relación con los métodos tradicionales, dirigidas al proceso de enseñanza-aprendizaje en este tema fue considerado en este trabajo como uno de los resultados obtenidos a la luz de los referenciales del aprendizaje significativo, tal como fueron fundamentados por Ausubel. Según la propuesta que aquí se presenta, la participación activa de los estudiantes en la ejecución de una actividad experimental y otras actividades educativas destinadas a la evaluación continua durante el proceso culminó en la elaboración de una historieta respecto de las fases de la Luna. Por lo tanto, el objetivo de este trabajo es presentar una propuesta de actividad de enseñanza diferenciada con el apoyo de los principios teóricos del aprendizaje significativo aplicado a la enseñanza de las fases de la luna durante las clases de física del ciclo secundario.

Martins, Bruno Andrade; Langhi, Rodolfo

2012-12-01

75

Vannevar Bush: Fifty Years Later  

NASA Astrophysics Data System (ADS)

It is ironic that the 50th anniversary year of Vannevar Bush's Report to President Truman entitled "Science the Endless Frontier", which put into motion the eminently successful current system of education of scientists in this country occurs at a time when serious questions are being asked about the usefulness of that very system. Bush viewed his proposal to establish a national research foundation (later to be called the National Science Foundation) as a "social compact." Judgment of scientific merit would be delegated to expert peers in return for scientific progress, which would ultimately benefit the nation in terms of scientific needs--military security, economic productivity, and enhanced quality of life. Bush wanted the funding of basic research intertwined with training, and preferred to use universities for this purpose rather than industrial or national labs. Bush viewed college and university scientists as teachers and investigators. He believed university-based research would uniquely encourage and engage the next generation of scientists as no other institutional arrangement could. Bush did not trust industry's commitment to basic research, an instinct that proved prophetic. The academic reserve of scientists (PhD's in training and postdoctoral students) that existed before World War II, and upon which the United States could draw for its needs, which were primarily associated with defense efforts, was probably one of the defining factors in Bush's suggested strategy. Currently, that reserve of talent has gotten so large that it is the obvious throttle in the pipeline slowing the continued development of the university research enterprise. Since 1977, the rate at which we have trained new scientists exceeds an average of 4% annually. Since 1987, the "science work force"--PhD's--has grown at three times the rate of the general labor supply. Temporary positions for postdoctoral scientists have grown even faster (over 5% per year since 1989). To compound the problem, the 1990 Immigration Reform Act resulted in a tripling of job-based visas, with scientists representing nearly one-third of the total. In 1979, two of every three postdoctoral scientists were U.S.-born; in 1992, the ratio was about one to one. Over that period, the cohort of postdoctoral scientists grew from 18,000 to 33,000. Adding to the coincidence of events that have compounded one another is the admission of 20,000 Chinese scientists in a ten-year period, the sudden and unexpected availability of Russian scientists, the elimination of many industrial laboratories as a result of downsizing, changes in the mandatory retirement age for faculty, and the disappearance of the Cold War, which all but eliminated the need for scientists for national security purposes. Is it any wonder that postdoctoral scientists have been called the migrant workers of today's high-tech society? What once was a reservoir of enthusiastic talent is becoming a dumping ground for credentialed and capable scientists exiled from the main stream of their disciplines. From a broader point of view, the problems facing U.S. science are those of our society: an imposing deficit that is shrinking discretionary funding; the end of the Cold War, which has refocused spending for national security; and a robust science work force that can no longer expand. The business world's response to these societal problems is, basically, downsizing, which often means the elimination of large segments of the work force, usually at the middle-management level. The initial academic response to these same problems is either to insist on more resources being made available, usually through federal agencies, in an attempt to maintain the status quo, or to engage in some form of "academic birth control." The former strategy is unrealistic because it just perpetuates the problem; there will never be enough research professorships in the academic world for every aspiring PhD produced in a discipline. The latter strategy will invariably decrease the flow of truly n

Lagowski, J. J.

1995-12-01

76

Function of lateral line canal morphology.  

PubMed

Fish perceive water motions and pressure gradients with their lateral line. Lateral line information is used for prey detection, spatial orientation, predator avoidance, schooling behavior, intraspecific communication and station holding. The lateral line of most fishes consists of superficial neuromasts (SNs) and canal neuromasts (CNs). The distribution of SNs and CNs shows a high degree of variation among fishes. Researchers have speculated for decades about the functional significance of this diversity, often without any conclusive answers. Klein et al. (2013) examined how tubules, pore number and pore patterns affect the filter properties of lateral line canals in a marine teleost, the black prickleback (Xiphister atropurpureus). A preliminary mathematical model was formulated and biomimetic sensors were built. For the present study the mathematical model was extended to understand the major underlying principle of how canal dimensions influence the filter properties of the lateral line. Both the extended mathematical model and the sensor experiments show that the number and distribution of pores determine the spatial filter properties of the lateral line. In an environment with little hydrodynamic noise, simple and complex lateral line canals have comparable response properties. However, if exposed to highly turbulent conditions, canals with numerous widely spaced pores increase the signal to noise ratio significantly. PMID:24920149

Klein, Adrian; Bleckmann, Horst

2015-01-01

77

Captura de satélites durante a formação de Júpiter  

NASA Astrophysics Data System (ADS)

O planeta Jupiter apresenta um grande número de satélites irregulares. As características das órbitas destes objetos indicam que os mesmos não teriam se formado ao redor do planeta que se encontram. As teorias existentes são de que estes objetos teriam se formado em uma região distante do planeta e sua evolução dinâmica os teria levado a uma captura gravitacional pelo planeta. Tendo em vista que o processo de captura gravitacional sem efeitos dissipativos não produz uma captura permanente, estudamos o processo de captura durante o estágio de formação do planeta. Realizamos simulações numéricas para os casos de satélites prógrados e retrógrados que inicialmente se encontram ao redor de Jupiter com sua massa atual e então, evoluimos a integração voltando no tempo de modo que o planeta sofra uma redução em sua massa (de 100% para 10% de sua massa atual) e verificamos o instante em que o satélites escapa do planeta (quando sua energia do problema de dois corpos se torna positiva). Assim, analisando o problema inverso no tempo, obtivemos em qual estágio de formação de Jupiter aquele hipotético satélite teria sido capturado. Os resultados mostram que os satélites retrógrados são capturados assim que entram na região delimitada pela esfera de Hill do planeta, enquanto que os satélites prógrados só são capturados quando entram numa região bem mais próxima ao planeta, uma fração da esfera de Hill.

Winter, O. C.; Vieira Neto, E.; Yokoyama, T.

2003-08-01

78

Laterality effects in cued auditory asymmetries.  

PubMed

The effect of cued attention on perceptual asymmetries was investigated with normal adults who differed in their lateral preference. Specifically, 15 right lateralized and a like number of mixed/left subjects were isolated on the basis of their lateral preference for visual guided motor activities. Learners' attention was directed to the left, right and both channels of dichotically presented verbal stimuli. Instructions to shift attention had little effect on the usual right-ear advantage for subjects who displayed a right of midline preference pattern. More bilateral subjects significantly improved their recognition of stimuli presented to the directed ear. PMID:7162591

Dean, R S; Hua, M S

1982-01-01

79

Rapid prototyping of lateral flow assays.  

PubMed

Principles and characteristics of lateral flow strip assays are reviewed. Recent technology developments permit the use of inexpensive electronic readers for interrogating lateral flow strip test results, thus avoiding the inevitable variation and subjectivity of visual inspection to assess the capture of reporter-labeled analyte on test lines of the strip. Protocols for developing lateral flow assays are described, including two specific case studies for assaying cotinine (a small-molecule metabolite of nicotine) in a competitive format, and assaying HIV antibodies in a sandwich-type assay format. PMID:19159100

Volkov, Alexander; Mauk, Michael; Corstjens, Paul; Niedbala, R Sam

2009-01-01

80

Surgical repair of ruptured lateral ankle ligaments  

Microsoft Academic Search

Fifty-two of 86 repaired lateral ankle ligaments were reevaluated 3 to 53 months after surgery. Ninety-eight percent were functionally stable. Mechanical stability was determined by talar tilt measurement on \\

Robert L. Brand; Myron D. F. Collins; Tom Templeton

1981-01-01

81

Septum formation of the lateral ventricles.  

PubMed

In an MRI study examining anomalies of the septum pellucidum in 505 cases, we detected bilateral septum formation of the lateral ventricles in a 17-month-old baby. In this study, we evaluate 505 (242 males and 263 females) patients referred to the Emaray Imaging Center, Ankara, Turkey with various prediagnoses. We specially selected all the cases from a non-psychotic population. We obtained MRI scans on a 1-Tesla imager (Picker International, Highland Heights, Ohio, USA), with slices of 5 and 6 mm thickness. In axial and coronal sections, we observed septum formation laterally between the anterior horn and the ventricular body of the lateral ventricles. Radio opaque septum formations started from the caudate nucleus and stretched to the genu of the corpus callosum. There was a second septum formation between the posterior horn and the ventricular body of the right lateral ventricle. It started from the caudate nucleus and stretched to the cavum vergae. PMID:16127534

Celik, Hakam H; Aldur, Mustafa M; Tatar, Ilkan; Ozkul, Emine; Tascioglu, Ayse B

2005-08-01

82

Alcohol Problems in lAter life  

E-print Network

Alcohol Problems in lAter life A Pacific Northwest Extension Publication Oregon State University When alcohol use becomes a problem ................. 4 How an alcohol problem develops ....................... 6 Recognizing an alcohol problem .......................... 8 Guidelines for family and friends

Tullos, Desiree

83

Cooling Therapy Helps Newborns Years Later  

MedlinePLUS

... Services Latest Issue This Issue Features Digging a Vegetarian Diet Massage Therapy Health Capsules Cooling Therapy Helps Newborns Years Later High Blood Pressure in Children Featured Website: Impact of NIH Research Past Issues ...

84

The lateral fixation screw in implant dentistry.  

PubMed

This clinical report presents a means of retaining implant supported superstructures using lateral fixation screws (Novadent). 244 lateral fixation screws have been used for the retention of a variety of restorations including single teeth, short span and full arch bridgework as well as overdenture bars. Over a period of observation of 4 years, the authors have found the restorations to have effective retention, ease of retrievability, good aesthetics and occlusal contours. PMID:11307389

Sethi, A; Sochor, P

2000-03-01

85

A Laterally Averaged Nonhydrostatic Ocean Model  

Microsoft Academic Search

Laterally-averaged dynamical equations are often used in numerical models of narrow coastal regions such as fjords and estuaries. Such models are preferable to 2D formulations, because they can handle variable-width effects such as flow acceleration at coastal constrictions. They also have a considerable speed advantage over 3D models. However, most laterally-averaged models share a significant weakness -- they rely on

Daniel Bourgault; Dan E. Kelley

2004-01-01

86

Brain and behavioral lateralization in invertebrates.  

PubMed

Traditionally, only humans were thought to exhibit brain and behavioral asymmetries, but several studies have revealed that most vertebrates are also lateralized. Recently, evidence of left-right asymmetries in invertebrates has begun to emerge, suggesting that lateralization of the nervous system may be a feature of simpler brains as well as more complex ones. Here I present some examples in invertebrates of sensory and motor asymmetries, as well as asymmetries in the nervous system. I illustrate two cases where an asymmetric brain is crucial for the development of some cognitive abilities. The first case is the nematode Caenorhabditis elegans, which has asymmetric odor sensory neurons and taste perception neurons. In this worm left/right asymmetries are responsible for the sensing of a substantial number of salt ions, and lateralized responses to salt allow the worm to discriminate between distinct salt ions. The second case is the fruit fly Drosophila melanogaster, where the presence of asymmetry in a particular structure of the brain is important in the formation or retrieval of long-term memory. Moreover, I distinguish two distinct patterns of lateralization that occur in both vertebrates and invertebrates: individual-level and population-level lateralization. Theoretical models on the evolution of lateralization suggest that the alignment of lateralization at the population level may have evolved as an evolutionary stable strategy in which individually asymmetrical organisms must coordinate their behavior with that of other asymmetrical organisms. This implies that lateralization at the population-level is more likely to have evolved in social rather than in solitary species. I evaluate this new hypothesis with a specific focus on insects showing different level of sociality. In particular, I present a series of studies on antennal asymmetries in honeybees and other related species of bees, showing how insects may be extremely useful to test the evolutionary hypothesis. PMID:24376433

Frasnelli, Elisa

2013-01-01

87

Brain and behavioral lateralization in invertebrates  

PubMed Central

Traditionally, only humans were thought to exhibit brain and behavioral asymmetries, but several studies have revealed that most vertebrates are also lateralized. Recently, evidence of left–right asymmetries in invertebrates has begun to emerge, suggesting that lateralization of the nervous system may be a feature of simpler brains as well as more complex ones. Here I present some examples in invertebrates of sensory and motor asymmetries, as well as asymmetries in the nervous system. I illustrate two cases where an asymmetric brain is crucial for the development of some cognitive abilities. The first case is the nematode Caenorhabditis elegans, which has asymmetric odor sensory neurons and taste perception neurons. In this worm left/right asymmetries are responsible for the sensing of a substantial number of salt ions, and lateralized responses to salt allow the worm to discriminate between distinct salt ions. The second case is the fruit fly Drosophila melanogaster, where the presence of asymmetry in a particular structure of the brain is important in the formation or retrieval of long-term memory. Moreover, I distinguish two distinct patterns of lateralization that occur in both vertebrates and invertebrates: individual-level and population-level lateralization. Theoretical models on the evolution of lateralization suggest that the alignment of lateralization at the population level may have evolved as an evolutionary stable strategy in which individually asymmetrical organisms must coordinate their behavior with that of other asymmetrical organisms. This implies that lateralization at the population-level is more likely to have evolved in social rather than in solitary species. I evaluate this new hypothesis with a specific focus on insects showing different level of sociality. In particular, I present a series of studies on antennal asymmetries in honeybees and other related species of bees, showing how insects may be extremely useful to test the evolutionary hypothesis. PMID:24376433

Frasnelli, Elisa

2013-01-01

88

Lateral tethering intraspinal lipoma with scoliosis  

Microsoft Academic Search

The authors present an unusual case of an intradural lipoma at the thoracolumbar level causing lateral tethering of the spine,\\u000a with complicated scoliosis. A 6-year-old girl was admitted with progressive change in posture detected by her parents. Thoracolumbar\\u000a scoliosis was detected by physical examination and X-ray studies. Spinal magnetic resonance imaging revealed an intradural\\u000a lipoma and right lateral tethering of

Bashar Abuzayed; Reza Dashti; Fatma Ozlen; Pamir Erdincler

2011-01-01

89

Colossus : El Secreto Mejor Guardado por los ingleses durante la Segunda Guerra Mundial 1  

E-print Network

Colossus : El Secreto Mejor Guardado por los ingleses durante la Segunda Guerra Mundial 1 Si la bomba atómica fue el secreto mejor guardado por los norteamericanos durante la Segunda Guerra Mundial Segunda Guerra Mundial'', Soluciones Avanzadas, Año 7, No. 69, pp. 3­4, mayo de 1999. 2 La PORS tenía

Coello, Carlos A. Coello

90

Lateralization of cognitive processes in the brain.  

PubMed

The lateralization of cognitive processes in the brain is discussed. The traditional view of a language-visuo/spatial dichotomy of function between the hemispheres has been replaced by more subtle distinctions. The use of magnetic resonance imaging (MRI) to study brain morphology has resulted in a renewed focus on the relationship between structural and functional asymmetry. Focus has been on the role played by the planum temporale area in the posterior part of the superior temporal gyrus for language asymmetry, and the possible significance of the larger left planum. The dichotic listening technique is used to illustrate the difference between bottom-up, or stimulus-driven laterality versus top-down, or instruction-driven laterality. It is suggested that the hemispheric dominance observed at any time is the sum result of the dynamic interaction between bottom-up and top-down processing tendencies. Stimulus-driven laterality dominance is always monitored and modulated through top-down cognitive processes, like shifting of attention and changes in arousal. A model of top-down modulation of bottom-up laterality is presented with special reference to the understanding of psychiatric disorders. PMID:11194413

Hugdahl, K

2000-12-01

91

Lateral restraint assembly for reactor core  

DOEpatents

A restraint assembly for use in restraining lateral movement of a reactor core relative to a reactor vessel wherein a plurality of restraint assemblies are interposed between the reactor core and the reactor vessel in circumferentially spaced relation about the core. Each lateral restraint assembly includes a face plate urged against the outer periphery of the core by a plurality of compression springs which enable radial preloading of outer reflector blocks about the core and resist low-level lateral motion of the core. A fixed radial key member cooperates with each face plate in a manner enabling vertical movement of the face plate relative to the key member but restraining movement of the face plate transverse to the key member in a plane transverse to the center axis of the core. In this manner, the key members which have their axes transverse to or subtending acute angles with the direction of a high energy force tending to move the core laterally relative to the reactor vessel restrain such lateral movement.

Gorholt, Wilhelm (San Diego, CA); Luci, Raymond K. (Del Mar, CA)

1986-01-01

92

Lateral flow immunoassay using magnetoresistive sensors  

NASA Astrophysics Data System (ADS)

Magnetic particles have been adapted for use as labels in biochemical lateral flow strip tests. Standard gold particle lateral flow assays are generally qualitative; however, with magnetic particles, quantitative results can be obtained by using electronic detection systems with giant magnetoresistive (GMR) sensors. As described here, these small integrated sensor chips can detect the presence of magnetic labels in capture spots whose volume is approximately 150 ?m×150 ?m×150 ?m. The range of linear detection is better than two orders of magnitude; the total range is up to four orders of magnitude. The system was demonstrated with both indirect and sandwich enzyme-linked immunosorbent assays (ELISAs) for protein detection of rabbit IgG and interferon-?, respectively, achieving detection of 12 pg/ml protein. Ultimately, the goal is for the detector to be fully integrated into the lateral flow strip backing to form a single consumable item that is interrogated by a handheld electronic reader.

Taton, Kristin; Johnson, Diane; Guire, Patrick; Lange, Erik; Tondra, Mark

2009-05-01

93

The Lateral Instability of Deep Rectangular Beams  

NASA Technical Reports Server (NTRS)

Experimental and analytical studies were made of solid and hollow deep rectangular beams to study their lateral instability under various conditions of loading and restraint. The tests were made on bars and tubes of 17ST aluminum alloy. Failure by lateral buckling occurred only in tests on the solid beams. It was found that, within the elastic range, the test results were in agreement with the classical theory for the lateral buckling of deep beams as given by Prandtl, Mitchell, and Timoshenko. The tests were extended to the inelastic range, where it was found that the substitution for Young's modulus of an average modulus of elasticity derived from the stress-strain curve made it possible to predict instability at high stresses.

Dumont, C; Hill, H N

1937-01-01

94

Salvage Surgery for Lateral Tennis Elbow  

Microsoft Academic Search

We undertook a retrospective analysis of 34 patients (35 elbows) who had prior failed surgical intervention for lateral tennis elbow. Revision surgeries were per formed between 1979 and 1994. Each patient's non operative and operative history was recorded before our salvage revision surgery. At revision surgery, find ings included residual tendinosis of the extensor carpi radialis brevis tendon in 34

Scott W. Organ; Robert P. Nirschl; Barry S. Kraushaar; Eric J. Guidi

1997-01-01

95

Balance problems after unilateral lateral ankle sprains  

Microsoft Academic Search

Ankle ligament injury is the most common injury in athletic activities. This study examined balance problems in ath- letes with acute lateral ankle sprains. Thirty male athletes aged 20 to 35 years with right dominant side and traumatic ankle sprain were recruited through simple nonprobability sampling. We measured the sway index and limits of stability with the Bio- dex Balance

Mohammad Akbari; Hossein Karimi; Hossein Farahini; Soghrat Faghihzadeh

2006-01-01

96

Phylogenetic identification of lateral genetic transfer events  

Microsoft Academic Search

BACKGROUND: Lateral genetic transfer can lead to disagreements among phylogenetic trees comprising sequences from the same set of taxa. Where topological discordance is thought to have arisen through genetic transfer events, tree comparisons can be used to identify the lineages that may have shared genetic information. An 'edit path' of one or more transfer events can be represented with a

Robert G Beiko; Nicholas Hamilton

2006-01-01

97

Breaking the news in amyotrophic lateral sclerosis  

Microsoft Academic Search

Telling the diagnosis to patients with amyotrophic lateral sclerosis (ALS) is a daunting task for any neurologist. Obviously, breaking the news in ALS is not a standardizable procedure. However, proven techniques exist to reduce the trauma to the patient and ease the burden on the doctor, thus reducing the risk of burnout and the tendency to `pull away' from the

Gian Domenico Borasio; Richard Sloan; Dieter E Pongratz

1998-01-01

98

Is migraine a lateralization defect? Jani Kaaroa  

E-print Network

Is migraine a lateralization defect? Jani Kaaroa , Timo Partonenb , Paulami Naikc and Nouchine.1097/WNR.0b013e32830c4698 Migraine often co-occurs with patent foramen ovale (PFO), and some people have suggested surgical closure as an e/cient treat- mentfor migraine.Prospective studies, however, do

Hadjikhani, Nouchine

99

The Columbine Tragedy Ten Years Later  

ERIC Educational Resources Information Center

Some tragedies are so emblazoned in people's minds that years later they can recall where they were when they first heard the news. The assassinations of John F. Kennedy and Martin Luther King Jr., the Challenger explosion, and the Sept. 11 terrorist attacks are among these events. So also is the Columbine High School tragedy of April 20, 1999.…

Hammond, Jane

2009-01-01

100

Profiling 1366 Technologies: One Year Later  

ScienceCinema

Last January, we took a look at how ARPA-E performer, 1366 Technologies is working to dramatically reduce the cost of solar energy. A year later, we revisited their headquarters in Lexington, MA to see the progress they've made.

Van Mierlo, Frank; Sachs, Ely;

2013-05-29

101

PROCEEDINGS Open Access Lateral gene transfer, rearrangement,  

E-print Network

Transfers. We examine two datasets of gene trees from a single set of cyanobacteria species. The first setPROCEEDINGS Open Access Lateral gene transfer, rearrangement, reconciliation Murray Patterson1 Abstract Background: Models of ancestral gene order reconstruction have progressively integrated different

Paris-Sud XI, Université de

102

Towards gene therapy in amyotrophic lateral sclerosis  

Microsoft Academic Search

Amyotrophic lateral sclerosis (ALS) is a paralytic neurodegenerative disorder, characterised by a specific loss of motoneurons. Although the exact pathogenesis is largely enigmatic, it is known that glutamate excitotoxicity plays an important role in motoneuron cell death. Glutamate is one of the major neurotransmitters in the central nervous system. Relative high levels of glutamate can lead to motoneuron death by

Liselijn Agatha Barendina Wisman

2004-01-01

103

Active Children: Healthy Now And Later  

ERIC Educational Resources Information Center

Current research is revealing that physical activity can protect against a range of lifestyle diseases and illnesses. Consequently, early childhood practitioners and parents need to adopt guidelines and practices which encourage children of all ages to be physically active. In "Active children: Healthy Now and Later," authors Linley Campbell and…

Campbell, Linley; Musumeci, Josephine

2005-01-01

104

Stem cell treatment in Amyotrophic Lateral Sclerosis  

Microsoft Academic Search

Amyotrophic Lateral Sclerosis is a progressive fatal neurodegenerative disease that targets motor neurons. Its origin is unknown but a main role of reactive astrogliosis and microglia activation in the pathogenesis has been recently demonstrated. Surrounding neurons with healthy adjoining cells completely stops motor neuron death in some cases. Hence stem cell transplantation might represent a promising therapeutic strategy. In this

Letizia Mazzini; Katia Mareschi; Ivana Ferrero; Elena Vassallo; Giuseppe Oliveri; Nicola Nasuelli; Gaia Donata Oggioni; Lucia Testa; Franca Fagioli

2008-01-01

105

Stem cell treatment in Amyotrophic Lateral Sclerosis  

Microsoft Academic Search

Amyotrophic Lateral Sclerosis is a progressive fatal neurodegenerative disease that targets motor neurons. Its origin is unknown but a main role of reactive astrogliosis and microglia activation in the pathogenesis has been recently demonstrated. Surrounding neurons with healthy adjoining cells completely stops motor neuron death in some cases. Hence stem cell transplantation might represent a promising therapeutic strategy. In this

Letizia Mazzini; Katia Mareschi; Ivana Ferrero; Elena Vassallo; Giuseppe Oliveri; Nicola Nasuelli; Gaia Donata Oggioni; Lucia Testa; Franca Fagioli

2007-01-01

106

Lateralized Temporal Order Judgement in Dyslexia  

ERIC Educational Resources Information Center

Temporal and spatial attentional deficits in dyslexia were investigated using a lateralized visual temporal order judgment (TOJ) paradigm that allowed both sensitivity to temporal order and spatial attentional bias to be measured. Findings indicate that adult participants with a positive screen for dyslexia were significantly less sensitive to the…

Liddle, Elizabeth B.; Jackson, Georgina M.; Rorden, Chris; Jackson, Stephen R.

2009-01-01

107

Simulation of lateral flow with SWAT  

Technology Transfer Automated Retrieval System (TEKTRAN)

Calibration of the SWAT model for the Goodwater Creek Experimental Watershed (GCEW) showed that percolation through the restrictive claypan layer, lateral flow above that layer, and redistribution of excess moisture up to the ground surface were not correctly simulated. In addition, surface runoff a...

108

Laterality, Implicit Memory, and Attention Disorder.  

ERIC Educational Resources Information Center

Presents study showing children with behaviors characteristic of attention disorder/hyperactivity deficit and high intelligence have more mixed laterality and allergies. Finds these children gather and use more diverse nonverbal and poorly focused information. Concludes such children use uncommon information when exhibiting novelty in nonverbal…

Shaw, Geraldine A.; Brown, Geoffrey

1991-01-01

109

Molecular basis of amyotrophic lateral sclerosis  

Microsoft Academic Search

Amyotrophic lateral sclerosis (ALS) is a fatal disorder of motor neuron degeneration with unclear etiology and no effective treatment to date. ALS is, however, increasingly recognized as a multisystem disorder associated with impaired cognition. The overlap between ALS and dementia at clinical, genetic and neuropathologic levels indicates a spectrum of clinical phenotypes that may include features of frontotemporal lobar degeneration

Rajka M. Liscic; Davorka Breljak

2011-01-01

110

Profiling 1366 Technologies: One Year Later  

SciTech Connect

Last January, we took a look at how ARPA-E performer, 1366 Technologies is working to dramatically reduce the cost of solar energy. A year later, we revisited their headquarters in Lexington, MA to see the progress they've made.

Van Mierlo, Frank; Sachs, Ely

2011-01-01

111

Control augmentation for lateral control wheel steering  

NASA Technical Reports Server (NTRS)

Flight control system design for lateral control wheel steering is discussed. Two alternate designs are presented. The first design is a roll-rate command, bank-angle hold system with a wings-level track-hold submode. The second is a curved-track-hold system. Design details and real-time flight simulator results are included.

Foulkes, R. H., Jr.

1981-01-01

112

Preparing Future Faculty: Ten Years Later  

ERIC Educational Resources Information Center

When Sean Murphy designed the Graduate Student Internship Program at the College of Lake County (CLC), his 2001 TETYC article about the then two-year-old program detailed his programmatic response to the job market. Ten years later, the CLC-DePaul University partnership remains the strongest of the original dozen cross-sector relationships CLC…

Murphy, Sean P.; Aiossa, Elizabeth; Winter, Mary Mugica

2010-01-01

113

Depression in Later Life: Recognition and Treatment.  

ERIC Educational Resources Information Center

This guide is designed to help readers understand depression and factors related to its onset in later life; recognize signs of depression and potential suicide; and know actions they can take if they suspect an older family member or friend may be depressed or contemplating suicide. Following a brief introduction, a chapter on depression…

Schmall, Vicki L.; And Others

114

Lateral capacity of helical piles in clays  

SciTech Connect

Helical piles, also known as screw anchors, consist of one or more helical-shaped circular plates welded to a central steel shaft at a specified spacing. Currently, helical piles are being used as tower foundations on land and in offshore areas to secure moorings, cables, and sea-bed pipelines to the sea bed. In this paper, the behavior of helical piles under lateral loads in clayey soils is examined through an experimental investigation on model piles. Tests were conducted on rigid helical piles with different numbers of plates. Model anchors were made of 13.8 mm diameter mild steel shafts to which mild steel plates of 33 mm diameter were welded. For comparison, a single straight shaft with a diameter of 13.8 mm was also tested. Test results revealed that the lateral capacity of helical piles is greater than that of straight shaft piles. A simple theoretical model is suggested to estimate the lateral capacity of rigid helical piles. The theoretical model suggested incorporates lateral resistance of the soil on the shaft, bearing resistance on the bottom of the helical plate, uplift resistance on the top of the helical plate, and frictional resistance on the surface of the helical plate. The validity of this model is examined.

Prasad, Y.V.S.N. [Memorial Univ. of Newfoundland, St. John`s, Newfoundland (Canada). Faculty of Engineering and Applied Science] [Memorial Univ. of Newfoundland, St. John`s, Newfoundland (Canada). Faculty of Engineering and Applied Science

1996-11-01

115

Measuring acetabular component position on lateral radiographs - ischio-lateral method.  

PubMed

The standard method for the evaluation of arthritis and postoperative assessment of arthroplasty treatment is observation and measurement from plain films, using the flm edge for orientation. A more recent employment of an anatomical landmark, the ischial tuberosity, has come into use as orientation for evaluation and is called the ischio-lateral method. In this study, the use of this method was evaluated as a first report to the literature on acetabular component measurement using a skeletal reference with lateral radiographs. Postoperative radiographs of 52 hips, with at least three true lateral radiographs taken at different time periods, were analyzed. Component position was measured with the historical method (using the flm edge for orientation) and with the new method using the ischio-lateral method. The mean standard deviation (SD) for the historical approach was 3.7° and for the ischio-lateral method, 2.2° (p < 0.001). With the historical method, 19 (36.5%) hips had a SD greater than ± 4°, compared to six hips (11.5%) with the ischio-lateral method. By using a skeletal reference, the ischio-lateral method provides a more consistent measurement of acetabular component position. The high intra-class correlation coefficients for both intra- and inter-observer reliability indicate that the angle measured with this simple method, which employs no further technology, increased time, or cost, is consistent and reproducible for multiple observers. PMID:22035491

Pulos, Nicholas; Tiberi Iii, John V; Schmalzried, Thomas P

2011-01-01

116

A convex lateral tibial plateau for knee replacement  

Microsoft Academic Search

Unicompartmental knee replacements have not performed as well in the lateral compartment as in the medial. This may be because the tibial components have flat or slightly concave surfaces which match the medial plateau but not the convex lateral plateau. The aim of this study was to find the optimal radius for a convex lateral tibial component.Twelve normal lateral tibial

J. V. Baré; H. S. Gill; D. J. Beard; D. W. Murray

2006-01-01

117

A rare nonincisional lateral abdominal wall hernia.  

PubMed

A 68-year-old woman presented a rare lateral abdominal wall hernia. Three month before admission to Chungbuk National University Hospital, she found a large protruding mass measuring 8 cm in diameter in the midaxillary line just below the costal margin upon heavy coughing. She had no history of abdominal trauma, infection, or operation previously. The mass was easily reduced manually or by position change to left lateral decubitus. CT scan showed a defect of the right transversus abdominis muscle and internal oblique muscle at the right flank with omental herniation. Its location is different from that of spigelian hernia or lumbar hernia. The peritoneal lining of the hernia sac was smooth and there was no evidence of inflammation or adhesion. The hernia was successfully repaired laparoscopically using Parietex composite mesh with an intraperitoneal onlay mesh technique. The patient was discharged uneventfully and did not show any evidence of recurrence at follow-up visits. PMID:25692123

Kim, Dong-Ju; Park, Jin-Woo

2015-02-01

118

A new integrative model of lateral epicondylalgia.  

PubMed

Tennis elbow or lateral epicondylalgia is a diagnosis familiar to many within the general community and presents with an uncomplicated clinical picture in most cases. However, the underlying pathophysiology presents a more complex state and its management has not been conclusively determined. Research on this topic extends across anatomical, biomechanical and clinical literature; however, integration of findings is lacking. We propose that the current understanding of the underlying pathophysiology of lateral epicondylalgia can be conceptualised as encompassing three interrelated components: (i) the local tendon pathology, (ii) changes in the pain system, and (iii) motor system impairments. This paper presents a model that integrates these components on the basis of a literature review with the express aim of assisting in the targeting of specific treatments or combinations thereof to individual patients. PMID:19050004

Coombes, B K; Bisset, L; Vicenzino, B

2009-04-01

119

A rare nonincisional lateral abdominal wall hernia  

PubMed Central

A 68-year-old woman presented a rare lateral abdominal wall hernia. Three month before admission to Chungbuk National University Hospital, she found a large protruding mass measuring 8 cm in diameter in the midaxillary line just below the costal margin upon heavy coughing. She had no history of abdominal trauma, infection, or operation previously. The mass was easily reduced manually or by position change to left lateral decubitus. CT scan showed a defect of the right transversus abdominis muscle and internal oblique muscle at the right flank with omental herniation. Its location is different from that of spigelian hernia or lumbar hernia. The peritoneal lining of the hernia sac was smooth and there was no evidence of inflammation or adhesion. The hernia was successfully repaired laparoscopically using Parietex composite mesh with an intraperitoneal onlay mesh technique. The patient was discharged uneventfully and did not show any evidence of recurrence at follow-up visits. PMID:25692123

Kim, Dong-Ju

2015-01-01

120

Traumatic lumbosacral lateral dislocation without fracture  

Microsoft Academic Search

Study design  A unique case of lumbosacral lateral dislocation without fracture is reported.\\u000a \\u000a \\u000a \\u000a Objective  To report on the diagnosis and treatment of a traumatic L5-S1 lateral dislocation in a polytrauma 34-year-old male with L5\\u000a nerve root paralysis.\\u000a \\u000a \\u000a \\u000a Method  Interbody fusion following decompression, posterior reduction and interbody grafting combined with posterior plating was performed.\\u000a \\u000a \\u000a \\u000a Results  At an early stage the patient was able to return

Federico De Iure; Stefania Paderni; Alessandro Gasbarrini; Stefano Bandiera; Stefano Boriani

2008-01-01

121

Planar microlens relay optics utilizing lateral focusing.  

PubMed

We have proposed a novel concept of planar microlens relay optics with the goal of realizing alignment-free and multifunctional integrated optical subsystems. Since the planar microlens is one of its key elements, its lateral focusing characteristics were examined. The measured focusing spot size was 3 microm x 7 microm, which is comparable with the core of single-mode optical fibers. By measuring the refractive-index distribution, we found that the planar microlens produced by the electromigration method has a desirable index distribution that resembles that of a Luneburg lens. Thus we conclude that planar microlens relay optics may be facilitated when the lateral focusing property of planar microlenses is used. PMID:20733703

Intani, D; Baba, T; Iga, K

1992-09-01

122

Thrust vectoring for lateral-directional stability  

NASA Technical Reports Server (NTRS)

The advantages and disadvantages of using thrust vectoring for lateral-directional control and the effects of reducing the tail size of a single-engine aircraft were investigated. The aerodynamic characteristics of the F-16 aircraft were generated by using the Aerodynamic Preliminary Analysis System II panel code. The resulting lateral-directional linear perturbation analysis of a modified F-16 aircraft with various tail sizes and yaw vectoring was performed at several speeds and altitudes to determine the stability and control trends for the aircraft compared to these trends for a baseline aircraft. A study of the paddle-type turning vane thrust vectoring control system as used on the National Aeronautics and Space Administration F/A-18 High Alpha Research Vehicle is also presented.

Peron, Lee R.; Carpenter, Thomas

1992-01-01

123

Epidural Abscess Masquerading as Lateral Sinus Thrombosis  

PubMed Central

Controversy regarding the use of anticoagulants, the evacuation of the sinus, or the use of medical treatment alone surrounds the treatment of lateral sinus thrombosis. Treatment of an epidural abscess associated with coalescent mastoiditis is much less controversial-drainage is usually recommended. The differing treatments of these complications mandate accurate diagnosis. The advent of more sophisticated radiological studies has facilitated diagnosis of these complications; however, tests are not infallible. We present three cases in which preoperative imaging demonstrates an epidural abscess mimicking lateral sinus thrombosis by compression of the vessel. A false-positive computed tomography (CT) or magnetic resonance imaging (MRI) study may lead to the wrong diagnosis and, consequently, improper treatment. In light of this possibility, we recommend surgical exploration in all such cases. ImagesFigure 1Figure 2Figure 3Figure 4 PMID:17171148

Brodner, David C.; Cutler, Jeff; Gianoli, Gerard J.; Amedee, Ronald G.

2000-01-01

124

Later Tertiary Leporidae of North America  

E-print Network

of enamel and dentine. Other terms used for more primitive leporids and for unworn teeth usually follow Woo]) (1940). Skele- tal terms follow BENSLEY (1945) in most cases. The term postalveolar foramen has been used to designate a fora- men for the passage...; lateral portion of nasal extends farther posteriorly than remainder; supraorbital process of frontal present; in palatine process of maxilla, foramen premolare (BoHLIN, 1942a, p. 59-60) absent. The combination of characters listed above differen- tiates...

Dawson, M. R.

1958-05-01

125

Quantifiable Lateral Flow Assay Test Strips  

NASA Technical Reports Server (NTRS)

As easy to read as a home pregnancy test, three Quantifiable Lateral Flow Assay (QLFA) strips used to test water for E. coli show different results. The brightly glowing control line on the far right of each strip indicates that all three tests ran successfully. But the glowing test line on the middle left and bottom strips reveal their samples were contaminated with E. coli bacteria at two different concentrations. The color intensity correlates with concentration of contamination.

2003-01-01

126

DISCUSSION 5: Transitions in the Later Palaeolithic  

Microsoft Academic Search

\\u000a This paper discusses a number of concepts common to “transitions” in the Later Palaeolithic, whether change should be multifaceted\\u000a in nature involving more than one cultural or technological attribute to be accepted as a defining point in time; the extent\\u000a to which rate of change is important, be it gradual, accelerated, punctuated or uniform, and whether duration of change is

Rupert A. Housley

127

Neck-proprioceptive influence on auditory lateralization  

Microsoft Academic Search

The effect of transcutaneous vibration of the posterior neck muscles on the lateralization of dichotic sound was investigated\\u000a in human subjects. Two-alternative forced-choice (left\\/right) judgements were made on acoustic stimuli presented with different\\u000a interaural level differences via headphones during neck-muscle vibration. A shift of the subjective auditory median plane\\u000a toward the side contralateral of vibration was found, indicating that the

Jörg Lewald; Hans-Otto Karnath; Walter H. Ehrenstein

1999-01-01

128

Lateral stability of the proximal interphalangeal joint.  

PubMed

Current diagnostic criteria and therapeutic guidelines for injuries to the collateral ligaments of the proximal interphalangeal (PIP) joint are imprecise and vague. Laxity determinations, failure analysis, radiographic stress testing, and microscopic dissections were performed on 112 PIP joints. The lateral collateral ligament (LCL) is the primary restraint to varus and valgus angulation of the PIP joint. Its palmar fibers are tight in joint extension and provide the first line of resistance to lateral angulation. Failure of the LCL almost always occurs proximally in a sequential fashion that begins with the palmar fibers and progresses to the more dorsal bundles. Proximal LCL disruption is followed by separation of the accessory collateral-LCL junction and finally by failure of the distal palmar plate. Midsubstance tears of the LCL are rare. If the lateral stress test shows more than 20 degrees of varus or valgus angulation, the LCL can be presumed to be completely disrupted. Angulation of less than 20 degrees is associated with a 53% chance of partial LCL failure and a 47% chance of complete disruption, but the proper position of the LCL will be maintained by the overlying connective tissues. A clinical investigation will be necessary to define the criteria for surgical intervention. PMID:3760491

Kiefhaber, T R; Stern, P J; Grood, E S

1986-09-01

129

Lateral dominance in children with learning disabilities.  

PubMed

The purpose of the study was to investigate the occurrence of lateral dominance problems in a sample of children with learning disabilities. Ninety-one children (62 boys, 29 girls) who attended a school for children with learning disabilities were selected for the study. The Harris tests of lateral dominance were administered individually, and the children were rated as having right, left, or mixed dominance for hand, eye, and foot. When compared with normative data on dominance in children, the results showed that the occurrence of mixed hand dominance was no more frequent, the occurrence of mixed eye dominance was less frequent, and the occurrence of mixed foot dominance was more frequent in the children with learning disabilities. Results also showed that the occurrence of mixed and crossed eye-hand dominance was significantly different in children with learning disabilities when compared with children without learning disabilities. However, the occurrence of mixed eye-hand dominance was found to be significantly greater in children without learning disabilities than in learning disabled children. Age and sex were not found to affect the occurrence of lateral dominance problems in children with learning disabilities. PMID:6823468

Connolly, B H

1983-02-01

130

Lateral jet injection into typical combustor flowfields  

NASA Technical Reports Server (NTRS)

The experimental problem of lateral jet injection into typical flow fields in the absence of combustion was studied. All flow fields being investigated have no expansion of the crossflow (the test section to swirler diameter ratio D/d = 1), after its passage through an optional swirler (with swirl vane angle phi = 0 (swirler removed), 45, and 70 degree). The lateral jet(s) is(are) located one test-section diameter downstream of the test-section inlet (x/D = 1). The lateral jets have round-sectioned nozzles, each of which has an area of 1/100th of the cross sectional area of the crossflow (A sub j/A sub c = 1/100). Jet-to-crossflow velocity ratios of R = v sub j/u sub o = 2, 4, and 6 were investigated. Helium-bubble low visualization, five-hole pitot probe time-mean velocity measurements, and single-wire time-mean velocity and normal and shear stress turbulence data were obtained in the research program.

Lilley, D. G.

1986-01-01

131

Lateral balance control for robotic gait training.  

PubMed

For the rehabilitation of neurological patients robot-aided gait training is increasingly being used. Lack of balance training in these robotic gait trainers might contribute to the fact that they do not live up to the expectations. Therefore, in this study we developed and evaluated an algorithm to support lateral balance during walking, through controlling pelvis motions. This algorithm assists the pelvis, according to a natural pelvic sway pattern, rather than attracting it to the middle of the treadmill. The support algorithm was tested on six healthy young subjects who walked on a treadmill, while different support gains were introduced. Using a higher support gain resulted in a closer approximation of the pelvic sway towards the reference pattern. Step width and step width variability reduced when the external stabilization was provided, and the stability margin increased. This indicates that artificial stabilization reduces the need for active lateral balance control. The presented algorithm to support lateral balance provides a way to assist balance in a more physiological way, compared to attracting the subject to the centre of the treadmill. Here the user is attracted/assisted towards a more natural weight shift pattern. This also facilitates a more natural input of the load receptors, which are largely involved in the regulation of muscle activation patterns and the transitions between the different gait phases. PMID:24187182

Koopman, B; Meuleman, J H; van Asseldonk, E H F; van der Kooij, H

2013-06-01

132

Laterally-biased quantum dot infrared photodetector  

NASA Astrophysics Data System (ADS)

At the Air Force Research Laboratory, Space Vehicles Directorate, we are interested in improving the performance of or modifying the capabilities of infrared detectors in order to locate and identify dim and/or distant objects in space. One characteristic we are very interested in is multicolor detection. To this end, we have turned to a novel detector design that we have come to call a Lateral Quantum Dot Infrared Photodetector (LQDIP). In this design, InAs quantum dots are buried in a GaAs quantum well, which in turn is tunnel-coupled to another GaAs quantum well. Photoexcited electrons from the quantum dots tunnel over to the second well and are then swept out via a lateral (perpendicular to the growth direction) bias voltage. This architecture should exhibit the ability to tune to select infrared frequencies with reduced dark current and unity gain. The lateral photocurrent is directed by a vertical (parallel to the growth direction) gate voltage. We will discuss this detector architecture and the LQDIP operating principles and conditions, and we will present some preliminary results of current-voltage, photocurrent, differential conductance, and spectral measurements.

Cardimona, D. A.; Morath, C. P.; Guidry, D. H.; Cowan, V. M.

2013-07-01

133

Painful lateral knee condyle bone marrow edema after treatment with lateral wedged insole.  

PubMed

A 50-yr-old man arrived at our department for a rehabilitation prescription after a right knee medial collateral ligament sprain. Magnetic resonance imaging showed medial collateral ligament partial rupture and medial femoral condyle increased signal intensity indicating bone edema. After treatment, the patient still complained of weight-bearing knee medial compartment pain. A lateral wedged insole was prescribed to decrease medial compartment compression forces. Initial response to insole use was good, but soon after, the patient complained of severe worsening knee pain. On examination, the lateral joint line and condyle palpation were tender. Insole use discontinuation was recommended, and another magnetic resonance imaging scan was performed. It showed an high T2-weighted signal intensity, representing bone marrow edema comprising a volume of 5 x 5 x 4.5 cm of lateral femoral condyle. Discontinuation of orthosis use relieved the pain, and the edema disappeared. To our knowledge, lateral femoral condyle painful bone marrow edema after lateral wedged insole use has not been previously described. The findings of this case report indicate that lateral wedged insole prescription should be carefully evaluated. PMID:20407310

Chaler, Joaquim; Torra, Mercè; Dolz, Josep Lluís; Müller, Bertram; Garreta, Roser

2010-05-01

134

Genetic factors and breast cancer laterality  

PubMed Central

Background Women are more likely to develop cancer in the left breast than the right. Such laterality may influence subsequent management, especially in elderly patients with heart disease who may require radiation therapy. The purpose of this study was to explore possible factors for such cancer laterality. Methods In this work, clinical data for consecutive patients with histologically confirmed breast cancer were reviewed, with emphasis on clinical presentation and family history. Results Between 2005 and 2012, 687 patients with breast cancer were seen. Two women with incomplete data and eleven men were excluded. In total, 343 (50.9%) patients presented with left breast cancer, 311 (46.1%) with right breast cancer, and 20 (3.0%) with simultaneous bilateral malignancy. There were no significant differences between the three groups, especially in regards to clinical presentation and tumor characteristics. A total of 622 (92.3%) patients had unilateral primary, 20 (3.0%) had simultaneous bilateral, and 32 (4.7%) had metachronous primary breast cancer with subsequent contralateral breast cancer after 7.5–236 months. The worst 10-year survival was for bilateral simultaneous (18%) compared with unilateral (28%) and metachronous primaries (90%). There were no differences in survival in relation to breast cancer laterality, handedness, and presence or absence of a family history of cancer. There were significant similarities between patients and first-degree relatives in regards to breast cancer laterality, namely same breast (30/66, 45.5%), opposite breast (9/66, 13.6%), and bilateral cancer (27/66, 40.9, P=0.01163). This was more evident among patients and their sisters (17/32, 53.1%) or mothers (11/27, 40.7%, P=0.0689). There were also close similarities in relation to age at initial diagnosis of cancer for patients and their first-degree relatives for age differences of ?5 years (48/166, 28.9%), 6–10 years (34/166, 20.5%), and >11 years (84/166, 50.6%, P=0.12065). Conclusion High similarities between patients and their first-degree relatives in regards to cancer laterality and possibly age at initial diagnosis of cancer may suggest an underlying inherited genetic predisposition. PMID:24790468

Amer, Magid H

2014-01-01

135

A lateral symmetrically bistable buckled beam  

NASA Astrophysics Data System (ADS)

We have micromachined a lateral symmetrically bistable buckled beam for snap-in holding structures by oxidizing released beams micromachined on thick silicon-on-insulator wafers. The wafers were prepared by bonding and chemical mechanical polishing, and the structures were fabricated by deep silicon reactive ion etching using the black silicon method, subsequently released and thermally oxidized. The bistability was monitored in situ in a scanning electron microscope using a micromanipulator. Guidelines for designing beams of an expected performance are given and arguments for considering beams that are not `fairly slender' have been found.

Vangbo, Mattias; Bäcklund, Ylva

1998-03-01

136

An anatomic and autologous lateral ankle stabilization.  

PubMed

A new technique for stabilization of the lateral ankle ligaments is presented. The procedure uses a split peroneus longus tendon to recreate the calcaneofibular and anterior talofibular ligaments. The new ligaments follow a precise anatomic course that replicates the pathway of the original ligaments. The procedure also capitalizes on interference screw technology so that accurate ligament tension can be obtained. This technique is most useful for severe ligamentous insufficiency involving both the calcaneofibular and anterior talofibular ligaments. Biomechanical rationale for the use of peroneus longus is also discussed. PMID:19857833

Schuberth, John M; Smith, Paul R; Jennings, Meagan M

2009-01-01

137

Towards reproducible, scalable lateral molecular electronic devices  

SciTech Connect

An approach to reproducibly fabricate molecular electronic devices is presented. Lateral nanometer-scale gaps with high yield are formed in Au/Pd nanowires by a combination of electromigration and Joule-heating-induced thermomechanical stress. The resulting nanogap devices are used to measure the electrical properties of small numbers of two different molecular species with different end-groups, namely 1,4-butane dithiol and 1,5-diamino-2-methylpentane. Fluctuations in the current reveal that in the case of the dithiol molecule devices, individual molecules conduct intermittently, with the fluctuations becoming more pronounced at larger biases.

Durkan, Colm, E-mail: cd229@eng.cam.ac.uk; Zhang, Qian [Nanoscience Centre, University of Cambridge, 9 JJ Thomson Avenue, Cambridge CB3 0FA (United Kingdom)

2014-08-25

138

Responsiveness-to-Intervention: A Decade Later  

PubMed Central

In this introduction to this special issue, “A Decade Later,” we provide an overview of the accomplishments as well as the persistent questions surrounding RTI. We organize this discussion within 3 categories: assessment, instruction, and policy. Within each of these sections, we also highlight how the articles in the present special issue expand upon the key issues. Developed initially for the early grades (kindergarten through third grade) and primarily in the area of reading, many-although not all-of these issues speak to the expansion of RTI to address a broader set of academic content areas and the full range of grade levels. PMID:22539056

Fuchs, Lynn S.; Vaughn, Sharon

2012-01-01

139

Towards reproducible, scalable lateral molecular electronic devices  

NASA Astrophysics Data System (ADS)

An approach to reproducibly fabricate molecular electronic devices is presented. Lateral nanometer-scale gaps with high yield are formed in Au/Pd nanowires by a combination of electromigration and Joule-heating-induced thermomechanical stress. The resulting nanogap devices are used to measure the electrical properties of small numbers of two different molecular species with different end-groups, namely 1,4-butane dithiol and 1,5-diamino-2-methylpentane. Fluctuations in the current reveal that in the case of the dithiol molecule devices, individual molecules conduct intermittently, with the fluctuations becoming more pronounced at larger biases.

Durkan, Colm; Zhang, Qian

2014-08-01

140

Quantifying Disease Progression in Amyotrophic Lateral Sclerosis  

PubMed Central

Amyotrophic lateral sclerosis (ALS) exhibits characteristic variability of onset and rate of disease progression, with inherent clinical heterogeneity making disease quantitation difficult. Recent advances in understanding pathogenic mechanisms linked to the development of ALS impose an increasing need to develop strategies to predict and more objectively measure disease progression. This review explores phenotypic and genetic determinants of disease progression in ALS, and examines established and evolving biomarkers that may contribute to robust measurement in longitudinal clinical studies. With targeted neuroprotective strategies on the horizon, developing efficiencies in clinical trial design may facilitate timely entry of novel treatments into the clinic. PMID:25223628

Simon, Neil G; Turner, Martin R; Vucic, Steve; Al-Chalabi, Ammar; Shefner, Jeremy; Lomen-Hoerth, Catherine; Kiernan, Matthew C

2014-01-01

141

Lateral tunneling through voltage-controlled barriers  

NASA Technical Reports Server (NTRS)

The paper reports on a detailed experimental investigation of lateral tunneling between electrodes of a two-dimensional electron gas separated by the voltage-controlled barrier of a nanometer Schottky gate. The experimental data are modeled using the WKB method to calculate the tunneling probability of electrons through a barrier whose shape is determined from a solution of the two-dimensional Poisson equation. This model is in excellent agreement with the experimental data over a two order of magnitude range of current.

Manion, S. J.; Bell, L. D.; Kaiser, W. J.; Maker, P. D.; Muller, R. E.

1991-01-01

142

AXR1 Acts after Lateral Bud Formation to Inhibit Lateral Bud Growth in Arabidopsis1  

PubMed Central

The AXR1 gene of Arabidopsis is required for many auxin responses. The highly branched shoot phenotype of mature axr1 mutant plants has been taken as genetic evidence for a role of auxin in the control of shoot branching. We compared the development of lateral shoots in wild-type Columbia and axr1-12 plants. In the wild type, the pattern of lateral shoot development depends on the developmental stage of the plant. During prolonged vegetative growth, axillary shoots arise and develop in a basal-apical sequence. After floral transition, axillary shoots arise rapidly along the primary shoot axis and grow out to form lateral inflorescences in an apical-basal sequence. For both patterns, the axr1 mutation does not affect the timing of axillary meristem formation; however, subsequent lateral shoot development proceeds more rapidly in axr1 plants. The outgrowth of lateral inflorescences from excised cauline nodes of wild-type plants is inhibited by apical auxin. axr1-12 nodes are resistant to this inhibition. These results provide evidence for common control of axillary growth in both patterns, and suggest a role for auxin during the late stages of axillary shoot development following the formation of the axillary bud and several axillary leaf primordia. PMID:10557232

Stirnberg, Petra; Chatfield, Steven P.; Leyser, H.M. Ottoline

1999-01-01

143

Medial patellar subluxation without previous lateral release: a case report.  

PubMed

Medial patellar subluxation (MPS) is normally described following a lateral release. We report on a 14-year-old girl with MPS without previous lateral release. Arthroscopic examination demonstrated MPS at 0 and 30° of flexion, and the patella was tight in flexion on the lateral side. A low lateral release with a tibial tubercle transfer was performed, followed by repair of the lateral release with an iliotibial band flap, and lateral patellofemoral ligament reconstruction. Excellent functional outcome was achieved. This type of patellar instability is often overlooked and a high index of suspicion is needed for appropriate diagnosis and treatment. PMID:24755851

Saper, Michael G; Shneider, David A

2014-07-01

144

Lateral Distribution Functions of Extensive Air Showers  

NASA Astrophysics Data System (ADS)

The energy is among the characteristics of Ultra High Energy Cosmic Rays (E>5 x 1019 eV) which could be estimated experimentally. The following paper attempts to estimate the energy of an UHECR proton by applying a Monte Carlo simulation code. A number of extensive air showers, vertical and inclined, is simulated to derive the Lateral Distribution Functions of the shower muons. The scenario of simulations is adopted to the Cerenkov surface detector of the P. AUGER Observatory. Due to the fact that the Lateral Distribution Functions show minimal fluctuations of the muon density at a distance larger than 800 m from the core of the showers, and due to the fact that at a distance of 900 m the distribution functions for inclined showers coincide (which means that it does not change with the zenith angle of the showers), we select the muon density at 900 m to derive the energy of the primary protons. (The project is co-funded by the European Social Fund and National Resources (EPEAEK II) PYTHAGORAS II.)

Geranios, A.; Fokitis, E.; Maltezos, S.; et al.

145

Lateral epicondylalgia: midlife crisis of a tendon.  

PubMed

The pathogenesis and management of lateral epicondylalgia, or tennis elbow, a common ailment affecting middle-aged subjects of both genders continue to provoke controversy. Currently it is thought to be due to local tendon pathology, pain system changes, and motor system impairment. Its diagnosis is usually clinical, based on a classical history, as well as symptoms and signs. In selected cases, additional imaging (X-rays, ultrasound, and magnetic resonance imaging) can help to confirm the diagnosis. Different treatment modalities have been described, including the use of orthotics, non-steroidal anti-inflammatory drugs, steroid injections, topical glyceryl trinitrate, exercise therapy, manual therapy, ultrasound therapy, laser therapy, extracorporeal shockwave therapy, acupuncture, taping, platelet-rich plasma injections, hyaluronan gel injections, botulinum toxin injections, and surgery. Nevertheless, evidence to select the best treatment is lacking and the choice of therapy depends on the experience of the management team, availability of the equipment and expertise, and patient response. This article provides a snapshot of current medical practice for lateral epicondylalgia management. PMID:24584568

Luk, James K H; Tsang, Raymond C C; Leung, H B

2014-04-01

146

Nappe emplacement under lateral pressure gradient  

NASA Astrophysics Data System (ADS)

New thin viscous approximation is under development specifically targeted to model spontaneous initiation and tens of kilometers horizontal displacement of tectonic nappes. Nappes are few kilometers thing and tens of kilometers long rock units trusted towards foreland often preserving internal lithological consistency and laying at near horizontal position at the end of the emplacement. Significant shear stresses and deviation of principal stresses from vertical is required to explain this very peculiar strain localization style from mechanical point of view. There is also a need for the explanation of their common appearances in most collisional settings. Both pure shear thin sheet and flexural models kinematically eliminate nappes formation. Spreading viscous sheet models, such as used to model glaciers, are also not applicable as the direction of motion is upward, against gravity. The reason for this discrepancy is the hydrostatic pressure approximation of the gravity-driven spreading models. Actually, the thin sheet approximation is not sensitive to the assumptions made on pressure profile. Lateral non-lithostatic pressure gradient-driven viscous sheet model is appropriate for modeling of nappes. In turn, significant non-lithostatic pressure must be supported by flexural rigidity of overlying and underlying units. Lateral gradients of this non-lithostatic pressure are responsible for the significant shear stress and, therefore, deviation of principal stress from vertical.

Podladchikov, Yury; Schmalholz, Stefan

2014-05-01

147

Dual-domain lateral shearing interferometer  

DOEpatents

The phase-shifting point diffraction interferometer (PS/PDI) was developed to address the problem of at-wavelength metrology of extreme ultraviolet (EUV) optical systems. Although extremely accurate, the fact that the PS/PDI is limited to use with coherent EUV sources, such as undulator radiation, is a drawback for its widespread use. An alternative to the PS/PDI, with relaxed coherence requirements, is lateral shearing interferometry (LSI). The use of a cross-grating, carrier-frequency configuration to characterize a large-field 4.times.-reduction EUV lithography optic is demonstrated. The results obtained are directly compared with PS/PDI measurements. A defocused implementation of the lateral shearing interferometer in which an image-plane filter allows both phase-shifting and Fourier wavefront recovery. The two wavefront recovery methods can be combined in a dual-domain technique providing suppression of noise added by self-interference of high-frequency components in the test-optic wavefront.

Naulleau, Patrick P.; Goldberg, Kenneth Alan

2004-03-16

148

Prototype cantilevers for quantitative lateral force microscopy  

SciTech Connect

Prototype cantilevers are presented that enable quantitative surface force measurements using contact-mode atomic force microscopy (AFM). The ''hammerhead'' cantilevers facilitate precise optical lever system calibrations for cantilever flexure and torsion, enabling quantifiable adhesion measurements and friction measurements by lateral force microscopy (LFM). Critically, a single hammerhead cantilever of known flexural stiffness and probe length dimension can be used to perform both a system calibration as well as surface force measurements in situ, which greatly increases force measurement precision and accuracy. During LFM calibration mode, a hammerhead cantilever allows an optical lever ''torque sensitivity'' to be generated for the quantification of LFM friction forces. Precise calibrations were performed on two different AFM instruments, in which torque sensitivity values were specified with sub-percent relative uncertainty. To examine the potential for accurate lateral force measurements using the prototype cantilevers, finite element analysis predicted measurement errors of a few percent or less, which could be reduced via refinement of calibration methodology or cantilever design. The cantilevers are compatible with commercial AFM instrumentation and can be used for other AFM techniques such as contact imaging and dynamic mode measurements.

Reitsma, Mark G.; Gates, Richard S.; Friedman, Lawrence H.; Cook, Robert F. [Nanomechanical Properties Group, National Institute of Standards and Technology, Gaithersburg, Maryland 20899 (United States)

2011-09-15

149

Revisiting cognitive rehearsal as an intervention against incivility and lateral violence in nursing: 10 years later.  

PubMed

Ten years ago, Griffin wrote an article on the use of cognitive rehearsal as a shield for lateral violence. Since then, cognitive rehearsal has been used successfully in several studies as an evidence-based strategy to address uncivil and bullying behaviors in nursing. In the original study, 26 newly licensed nurses learned about lateral violence and used cognitive rehearsal techniques as an intervention for nurse-to-nurse incivility. The newly licensed nurses described using the rehearsed strategies as difficult, yet successful in reducing or eliminating incivility and lateral violence. This article updates the literature on cognitive rehearsal and reviews the use of cognitive rehearsal as an evidence-based strategy to address incivility and bullvina behaviors in nursing. PMID:25406637

Griffin, Martha; Clark, Cynthia M

2014-12-01

150

Strath Terraces, Lateral Planation, and Sediment Supply  

NASA Astrophysics Data System (ADS)

Abandoned fluvially eroded bedrock surfaces (strath terraces) are used ubiquitously as indicators of past river elevation. However, little is known about how, why and over what time period they form. Consequently, dates of strath surfaces, or overlying gravels, can be difficult to interpret without a more mechanistic understanding of strath genesis. We mapped strath terraces in detail in the field along the South Fork Eel River and its tributaries in the California Coast Ranges to illuminate the process(es) of lateral bedrock planation. We document two straths along the South Fork Eel: a high strath terrace with a bedrock surface at 9-12 m above the modern low water line and a low strath terrace with a bedrock elevation 2-5 m above modern low water line. Straths are capped with up to 6 meters of gravel, and are locally as much as 3 times the width of the modern river channel. The South Fork Eel incises interbedded sandstone and mudstone of the Franciscan Complex. Straths are usually, but not always, formed in the weaker mudstone. This is consistent with observations in the active river channel indicating mudstone is readily planed down to the low water line by weathering processes and abrasion, whereas sandstone forms resistant ribs that locally constrict the flow. Our observations suggest at least two primary mechanisms drive the lateral planation essential to preserving straths. First, many strath terraces along the South Fork Eel are exposed at the toe of inactive debris fans that entered the channel from tributaries and graded to the higher strath elevation. In these settings, the river has almost always cut vertically through the strath between the outside edge of the fan and a bedrock wall. We interpret this as evidence that when the debris fan was active and the river occupied the high strath, the river was pinned by the debris fan against a bedrock valley wall. This, in turn, suggests lateral sediment input from fans may be important in driving lateral motion of the river. Second, where there is no significant lateral sediment input, straths appear to form at channel meanders. Observations in the active channel suggest that mudstone bedrock will erode much more readily than bars or fans, which are both comprised almost entirely of resistant sandstone boulders. We hypothesize that deposition of point bars, island bars, and debris fans therefore provides a mechanism to preferentially armor one bank of an active channel, leading to erosion of the other bank where mudstone is present. Importantly, along the South Fork Eel the majority of straths appear to form unidirectionally, that is via one continuous sweep of the channel across the strath. Recent dating of strath terraces along the South Fork Eel by others (and additional samples awaiting dating) will be used to evaluate this hypothesis. We assess recent proposals that strath terrace formation on the South Fork Eel is associated with a doubling of hillslope erosion by running HEC- RAS on a LiDAR DEM of the South Fork Eel to model bed sediment transport and bed evolution under different sediment supply scenarios. A primary goal is to explore how up to 6 m of aggradation could be associated with strath terrace formation.

Finnegan, N. J.; Dietrich, W. E.

2008-12-01

151

Macroscopic Lateral Heterogeneity Observed in a Laterally-Mobile Immiscible Mixed Polyelectrolyte/Neutral Polymer Brush  

PubMed Central

We studied mixed poly(ethylene oxide) (PEO) and poly(2-(dimethylamino)ethyl methacrylate) (PDMAEMA) brushes. The question we attempted to answer was: When the chain grafting points are laterally mobile, how will this lateral mobility influence the structure and phase behavior of the mixed brush? Three different model mixed PEO/PDMAEMA brush systems were prepared: (1) a laterally-mobile mixed brush by spreading onto the air-water interface a mixture of poly(ethylene oxide)-poly(n-butyl acrylate) (PEO-PnBA) and poly(2-(dimethylamino)ethyl methacrylate)-poly(n-butyl acrylate) (PDMAEMA-PnBA) diblock copolymers (the specific diblock copolymers used will be denoted as PEO113-PnBA100 and PDMAEMA118-PnBA100, where the subscripts refer to the number-average degrees of polymerization of the individual blocks), (2) a mobility-restricted (inseparable) version of the above mixed brush prepared using a PEO-PnBA-PDMAEMA triblock copolymer (denoted as PEO113-PnBA89-PDMAEMA120) having respective brush molecular weights matched to those of the diblock copolymers, and (3) a different laterally-mobile mixed PEO and PDMAEMA brush prepared from a PEO113-PnBA100 and PDMAEMA200-PnBA103 diblock copolymer combination, which represents a further more height-mismatched mixed brush situation than described in (1). These three mixed brush systems were investigated by surface pressure-area isotherm and X-ray (XR) reflectivity measurements. These experimental data were analyzed within the theoretical framework of a continuum self-consistent field (SCF) polymer brush model. The combined experimental and theoretical results suggest that the mobile mixed brush derived using the PEO113-PnBA100 and PDMAEMA118-PnBA100 combination (i.e., Mixed Brush System #1) undergoes a lateral macroscopic phase separation at high chain grafting densities, whereas the more height-mismatched system (System #3) is only microscopically phase separated under comparable brush density conditions even though the lateral mobility of the grafted chains is unrestricted. The macroscopic phase separation observed in the laterally-mobile mixed brush system is in contrast to the microphase separation behavior commonly observed in two-dimensional laterally-mobile charged small molecule mixtures. Further study is needed to determine the detailed morphologies of the macro and microphase-separated mixed PEO/PDMAEMA brushes. PMID:24695635

Lee, Hoyoung; Tsouris, Vasilios; Lim, Yunho; Mustafa, Rafid; Choi, Je; Choi, Yun Hwa; Park, Hae-Woong; Meron, Mati; Lin, Binhua; Won, You-Yeon

2015-01-01

152

Macroscopic lateral heterogeneity observed in a laterally mobile immiscible mixed polyelectrolyte-neutral polymer brush.  

PubMed

We studied mixed poly(ethylene oxide) (PEO) and poly(2-(dimethylamino)ethyl methacrylate) (PDMAEMA) brushes. The question we attempted to answer was: when the chain grafting points are laterally mobile, how will this lateral mobility influence the structure and phase behavior of the mixed brush? Three different model mixed PEO/PDMAEMA brush systems were prepared: (1) a laterally mobile mixed brush by spreading onto the air-water interface a mixture of poly(ethylene oxide)-poly(n-butyl acrylate) (PEO-PnBA) and poly(2-(dimethylamino)ethyl methacrylate)-poly(n-butyl acrylate) (PDMAEMA-PnBA) diblock copolymers (the specific diblock copolymers used will be denoted as PEO113-PnBA100 and PDMAEMA118-PnBA100, where the subscripts refer to the number-average degrees of polymerization of the individual blocks), (2) a mobility-restricted (inseparable) version of the above mixed brush prepared using a PEO-PnBA-PDMAEMA triblock copolymer (denoted as PEO113-PnBA89-PDMAEMA120) having respective brush molecular weights matched with those of the diblock copolymers, and (3) a different laterally mobile mixed PEO and PDMAEMA brush prepared from a PEO113-PnBA100 and PDMAEMA200-PnBA103 diblock copolymer combination, which represents a further more height-mismatched mixed brush situation than described in (1). These three mixed brush systems were investigated by surface pressure-area isotherm and X-ray (XR) reflectivity measurements. These experimental data were analyzed within the theoretical framework of a continuum self-consistent field (SCF) polymer brush model. The combined experimental and theoretical results suggest that the mobile mixed brush derived using the PEO113-PnBA100 and PDMAEMA118-PnBA100 combination (i.e., mixed brush System #1) undergoes a lateral macroscopic phase separation at high chain grafting densities, whereas the more height-mismatched system (System #3) is only microscopically phase separated under comparable brush density conditions even though the lateral mobility of the grafted chains is unrestricted. The macroscopic phase separation observed in the laterally mobile mixed brush system is in contrast with the microphase separation behavior commonly observed in two-dimensional laterally mobile charged small molecule mixtures. Further study is needed to determine the detailed morphologies of the macro- and microphase-separated mixed PEO/PDMAEMA brushes. PMID:24695635

Lee, Hoyoung; Tsouris, Vasilios; Lim, Yunho; Mustafa, Rafid; Choi, Je; Choi, Yun Hwa; Park, Hae-Woong; Meron, Mati; Lin, Binhua; Won, You-Yeon

2014-06-01

153

Magnetic resonance imaging in lateral sinus hypoplasia and thrombosis.  

PubMed

Lateral sinus thrombosis may be difficult to differentiate angiographically from lateral sinus hypoplasia, which mainly affects its proximal transverse portion. Using magnetic resonance imaging, we evaluated six patients who demonstrated poor filling or lack of filling of one or both lateral sinuses at angiography. In each patient, magnetic resonance imaging unambiguously demonstrated either lateral sinus thrombosis or lateral sinus hypoplasia. The latter was characterized by a frank asymmetry in size (surface of section) of the transverse portion of the lateral sinuses on parasagittal images without any abnormal signal in the course of the sinus. Lateral sinus thrombosis was indicated by increased intraluminal signal on all planes and with all pulse sequences. By virtue of its freedom from bone-related artifact, its multiplanar imaging capability, and its sensitivity to both blood flow and thrombus formation, magnetic resonance imaging is an excellent tool for the evaluation of lateral sinus thrombosis or hypoplasia. PMID:2396274

Mas, J L; Meder, J F; Meary, E; Bousser, M G

1990-09-01

154

Diagnosis and Treatment of Lateral Patellar Compression Syndrome  

PubMed Central

Chronic anterior knee pain with a stable patella is often associated with overload and increased pressure on the lateral facet due to pathologic lateral soft-tissue restraints. “Lateral pressure in flexion” is a term describing the pathologic process of increasing contact pressure over the lateral patellar facet as knee flexion progresses. This report describes a surgical technique developed in response to lateral pressure in flexion and the shortcomings of traditional arthroscopic lateral release procedures. The technique is performed open with the knee in flexion, and the lateral release is repaired with a rotation flap of iliotibial band to close the defect and prevent patellar subluxation. The technique effectively decreases lateral patellar pressure and centers the patella correctly in the trochlear groove with minimal risk of iatrogenic patellar instability. PMID:25473620

Saper, Michael G.; Shneider, David A.

2014-01-01

155

In situ hydrodynamic lateral force calibration of AFM colloidal probes.  

PubMed

Lateral force microscopy (LFM) is an application of atomic force microscopy (AFM) to sense lateral forces applied to the AFM probe tip. Recent advances in tissue engineering and functional biomaterials have shown a need for the surface characterization of their material and biochemical properties under the application of lateral forces. LFM equipped with colloidal probes of well-defined tip geometries has been a natural fit to address these needs but has remained limited to provide primarily qualitative results. For quantitative measurements, LFM requires the successful determination of the lateral force or torque conversion factor of the probe. Usually, force calibration results obtained in air are used for force measurements in liquids, but refractive index differences between air and liquids induce changes in the conversion factor. Furthermore, in the case of biochemically functionalized tips, damage can occur during calibration because tip-surface contact is inevitable in most calibration methods. Therefore, a nondestructive in situ lateral force calibration is desirable for LFM applications in liquids. Here we present an in situ hydrodynamic lateral force calibration method for AFM colloidal probes. In this method, the laterally scanned substrate surface generated a creeping Couette flow, which deformed the probe under torsion. The spherical geometry of the tip enabled the calculation of tip drag forces, and the lateral torque conversion factor was calibrated from the lateral voltage change and estimated torque. Comparisons with lateral force calibrations performed in air show that the hydrodynamic lateral force calibration method enables quantitative lateral force measurements in liquid using colloidal probes. PMID:21905684

Ryu, Sangjin; Franck, Christian

2011-11-01

156

ELECTRICAL RESPONSES FROM LATERAL-LINE NERVES OF FISHES. III  

PubMed Central

Evidence indicates that lateral-line fibers, other than those mediating the "spontaneous" activity of the lateral-line receptors, are brought into play in response to pressure stimuli in catfish and in trout. The distribution and mode of stimulation of mechanoreceptors along the lateral-lines of trout and catfish are discussed in relation to the natural activities of these forms. PMID:19872765

Hoagland, Hudson

1933-01-01

157

Predicting Later-Life Outcomes of Early-Life Exposures  

EPA Science Inventory

Background: In utero exposure of the fetus to a stressor can lead to disease in later life. Epigenetic mechanisms are likely mediators of later-life expression of early-life events.Objectives: We examined the current state of understanding of later-life diseases resulting from ea...

158

Superficial lateral line sense organs of the mudminnow ( Umbra limi )  

Microsoft Academic Search

Umbra limi has an elaborate developement of superficial neuromasts on the head and body. The individual lateral line organs of the head form rows. Intermittant clusters of organs occur on the body. The “lateral line“ consists of free standing organs, which are oriented alternating horizontally and vertically. A lateral line canal is wanting.

Erich Schwartz; Arthur D. Hasler

1966-01-01

159

Sex Differences in Cerebral Laterality of Language and Visuospatial Processing  

ERIC Educational Resources Information Center

Sex differences on language and visuospatial tasks are of great interest, with differences in hemispheric laterality hypothesized to exist between males and females. Some functional imaging studies examining sex differences have shown that males are more left lateralized on language tasks and females are more right lateralized on visuospatial…

Clements, A. M.; Rimrodt, S. L.; Abel, J. R.; Blankner, J. G.; Mostofsky, S. H.; Pekar, J. J.; Denckla, M. B.; Cutting, L. E.

2006-01-01

160

The management of the popliteus hiatus during lateral meniscal transplantation.  

PubMed

Popliteofascicular injury had been proposed as a possible cause of unstable lateral meniscus. Meniscal repair at popliteal hiatus area during lateral meniscal allograft transplantation (MAT) had not been described in literature previously. In this report, a case of unstable lateral meniscus after MAT has been described. Arthroscopic repair for the unstable meniscus at popliteal hiatus resolved the mechanical symptom. PMID:22578893

Yang, Jae-Hyuk; Jeong, Hyeon-Il; Kim, Taik-Sun; Park, Sung-Chul; Yoon, Jung-Ro

2012-12-01

161

The Relationship Between Lateral Dominance and Divergent Cognitive Thought.  

ERIC Educational Resources Information Center

This study was designed to explore the relationship of lateral dominance to divergent cognitive thought. According to the screening results of the Harris Tests of Lateral Dominance, 36 subjects ranging from 9-12 years were divided equally into three groups of left, right, and mixed lateral dominance. In order to measure divergent cognitive…

Williams, Barbara B.

162

Lateralized eye use in Octopus vulgaris shows antisymmetrical distribution  

Microsoft Academic Search

Behavioural lateralization has been demonstrated in many species of vertebrates, but there has been scarce evidence for it in invertebrates. We have previously documented lateral asymmetry of eye use in individual octopuses. In the present study we investigated lateralization at the population level. Octopus eyes are on the sides of the head, and these animals prefer monocular to binocular vision.

Ruth A. Byrne; Michael J. Kuba; Daniela V. Meisel

2004-01-01

163

Autoimmune disease preceding amyotrophic lateral sclerosis  

PubMed Central

Objective: To study whether the risk of amyotrophic lateral sclerosis (ALS) is increased in people with prior autoimmune disease. Methods: An all-England hospital record-linkage dataset spanning 1999–2011 was used. Cohorts were constructed of people with each of a range of autoimmune diseases; the incidence of ALS in each disease cohort was compared with the incidence of ALS in a cohort of individuals without prior admission for the autoimmune disease. Results: There were significantly more cases than expected of ALS associated with a prior diagnosis of asthma, celiac disease, younger-onset diabetes (younger than 30 years), multiple sclerosis, myasthenia gravis, myxedema, polymyositis, Sjögren syndrome, systemic lupus erythematosus, and ulcerative colitis. Conclusions: Autoimmune disease associations with ALS raise the possibility of shared genetic or environmental risk factors. PMID:23946298

Goldacre, Raph; Ramagopalan, Sreeram; Talbot, Kevin; Goldacre, Michael J.

2013-01-01

164

Large-scale lateral nanowire arrays nanogenerators  

DOEpatents

In a method of making a generating device, a plurality of spaced apart elongated seen members are deposited onto a surface of a flexible non-conductive substrate. An elongated conductive layer is applied to a top surface and a first side of each seed member, thereby leaving an exposed second side opposite the first side. A plurality of elongated piezoelectric nanostructures is grown laterally from the second side of each seed layer. A second conductive material is deposited onto the substrate adjacent each elongated first conductive layer so as to be soupled the distal end of each of the plurality of elongated piezoelectric nanostructures. The second conductive material is selected so as to form a Schottky barrier between the second conductive material and the distal end of each of the plurality of elongated piezoelectric nanostructures and so as to form an electrical contact with the first conductive layer.

Wang, Zhong L; Xu, Chen; Qin, Yong; Zhu, Guang; Yang, Rusen; Hu, Youfan; Zhang, Yan

2014-01-07

165

Amyotrophic lateral sclerosis: update and new developments  

PubMed Central

Amyotrophic lateral sclerosis (ALS) is the most common form of motor neuron disease. It is typically characterized by adult-onset degeneration of the upper and lower motor neurons, and is usually fatal within a few years of onset. A subset of ALS patients has an inherited form of the disease, and a few of the known mutant genes identified in familial cases have also been found in sporadic forms of ALS. Precisely how the diverse ALS-linked gene products dictate the course of the disease, resulting in compromised voluntary muscular ability, is not entirely known. This review addresses the major advances that are being made in our understanding of the molecular mechanisms giving rise to the disease, which may eventually translate into new treatment options. PMID:23019386

Pratt, Ashley J; Getzoff, Elizabeth D; Perry, J Jefferson P

2012-01-01

166

Inertia and scaling in deterministic lateral displacement  

PubMed Central

The ability to separate and analyze chemical species with high resolution, sensitivity, and throughput is central to the development of microfluidics systems. Deterministic lateral displacement (DLD) is a continuous separation method based on the transport of species through an array of obstacles. In the case of force-driven DLD (f-DLD), size-based separation can be modelled effectively using a simple particle-obstacle collision model. We use a macroscopic model to study f-DLD and demonstrate, via a simple scaling, that the method is indeed predominantly a size-based phenomenon at low Reynolds numbers. More importantly, we demonstrate that inertia effects provide the additional capability to separate same size particles but of different densities and could enhance separation at high throughput conditions. We also show that a direct conversion of macroscopic results to microfluidic settings is possible with a simple scaling based on the size of the obstacles that results in a universal curve. PMID:24396545

Bowman, Timothy J.; Drazer, German; Frechette, Joelle

2013-01-01

167

Genetics of amyotrophic lateral sclerosis: an update  

PubMed Central

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder involving both upper motor neurons (UMN) and lower motor neurons (LMN). Enormous research has been done in the past few decades in unveiling the genetics of ALS, successfully identifying at least fifteen candidate genes associated with familial and sporadic ALS. Numerous studies attempting to define the pathogenesis of ALS have identified several plausible determinants and molecular pathways leading to motor neuron degeneration, which include oxidative stress, glutamate excitotoxicity, apoptosis, abnormal neurofilament function, protein misfolding and subsequent aggregation, impairment of RNA processing, defects in axonal transport, changes in endosomal trafficking, increased inflammation, and mitochondrial dysfunction. This review is to update the recent discoveries in genetics of ALS, which may provide insight information to help us better understanding of the disease neuropathogenesis. PMID:23941283

2013-01-01

168

Bilayer Graphene Lateral Contacts for DNA Sequencing  

E-print Network

Translocation of DNA through a nanopore with embedded electrodes is at the centre of new rapid inexpensive sequencing methods which allow distinguishing the four nucleobases by their different electronic structure. However, the subnanometer separation between nucleotides in DNA requires ultra-sharp probes. Here, we propose a device architecture consisting of a nanopore formed in bilayer graphene, with the two layers acting as separate electrical contacts. The 0.34 nm interlayer distance of graphene is ideally suited for electrical coupling to a single nucleobase, avoiding the difficulty of fabricating probes with subnanometer precision. The top and bottom graphene electrodes contact the target molecule from the same lateral side, removing the orders-of-magnitude tunneling current variations between smaller pyrimidine bases and larger purine bases. We demonstrate that incorporating techniques for molecular manipulation enables the proposed device to sequence single-stranded DNA and that it offers even the pros...

He, Yuhui; Scheicher, Ralph H; Taniguchi, Masateru; Kawai, Tomoji

2012-01-01

169

Optical fiber head for providing lateral viewing  

DOEpatents

The head of an optical fiber comprising the sensing probe of an optical heterodyne sensing device includes a planar surface that intersects the perpendicular to axial centerline of the fiber at a polishing angle .theta.. The planar surface is coated with a reflective material so that light traveling axially through the fiber is reflected transverse to the fiber's axial centerline, and is emitted laterally through the side of the fiber. Alternatively, the planar surface can be left uncoated. The polishing angle .theta. must be no greater than 39.degree. or must be at least 51.degree.. The emitted light is reflected from adjacent biological tissue, collected by the head, and then processed to provide real-time images of the tissue. The method for forming the planar surface includes shearing the end of the optical fiber and applying the reflective material before removing the buffer that circumscribes the cladding and the core.

Everett, Matthew J. (Livermore, CA); Colston, Billy W. (Livermore, CA); James, Dale L. (Tracy, CA); Brown, Steve (Livermore, CA); Da Silva, Luiz (Danville, CA)

2002-01-01

170

Motoneuron firing in amyotrophic lateral sclerosis (ALS)  

PubMed Central

Amyotrophic lateral sclerosis is an inexorably progressive neurodegenerative disorder involving the classical motor system and the frontal effector brain, causing muscular weakness and atrophy, with variable upper motor neuron signs and often an associated fronto-temporal dementia. The physiological disturbance consequent on the motor system degeneration is beginning to be well understood. In this review we describe aspects of the motor cortical, neuronal, and lower motor neuron dysfunction. We show how studies of the changes in the pattern of motor unit firing help delineate the underlying pathophysiological disturbance as the disease progresses. Such studies are beginning to illuminate the underlying disordered pathophysiological processes in the disease, and are important in designing new approaches to therapy and especially for clinical trials. PMID:25294995

de Carvalho, Mamede; Eisen, Andrew; Krieger, Charles; Swash, Michael

2014-01-01

171

Mechanical contributions to chronic lateral ankle instability.  

PubMed

Lateral ankle sprains are one of the most common athletic injuries. Even more concerning is the high recurrence rate after an initial sprain. The development of repetitive ankle sprains and persistent symptoms after injury has been termed chronic ankle instability (CAI). One of the purported causes of CAI is mechanical ankle instability (MAI).MAI results in abnormal ankle mechanics. Both hypermobility and hypomobility may change a joint's axis of rotation and result in abnormal joint mechanics. The role of hypermobility, or laxity, has been examined extensively in the literature, but more recently the role of hypomobility has also been examined. There may be a relationship between the two, with implications at the talocrural, subtalar, and inferior tibiofibular joints.Assessment and treatment should focus on both hypermobility and hypomobility and although injury may seem to be isolated to the talocrural joint, the inferior tibiofibular and subtalar joints should also be thoroughly examined. PMID:16526836

Hubbard, Tricia J; Hertel, Jay

2006-01-01

172

The never-married in later life.  

PubMed

Sources or consequences of singlehood are analyzed for the 162 never-married persons aged 50 and over from the six years of the NORC General Social Surveys. Highly-educated older women are most likely to remain single, but family background was not a predictor. Although the never-married find life more exciting than other marital statuses among younger (25 to 49) respondents, this reverses in later life. The never-married are also less happy than the married, and only slightly happier than the widowed and divorced. The characteristic that best explains their relative unhappiness is greater dissatisfaction with family life. The lower well-being of the never-married is attributable either to changes accompanying aging which lessen the viability of single life styles, or to less support of single living among current older cohorts. PMID:512306

Ward, R A

1979-11-01

173

EAS-BUAP: Lateral Distribution and Performance  

NASA Astrophysics Data System (ADS)

We describe the operation and performance of the first stage of the EAS-UAP extensive air shower array, as a detector of very high energy cosmic rays (Eo > 1014eV) after one year of operation. The array is located at the Campus of Puebla University, 2200 m above sea level. It consists of 10 liquid scintillator detectors, each with an active surface of 1 m2 and a detector spacing of 20 m in a square grid. One Auger Water Cherenkov detector is also included as part of the array. In this report we discuss the stability, the calibration and lateral distribution function reconstruction capabilities of the detector array. We also present the analysis of the shower size spectrum. In addition, the main characteristics of this array allow us to use it as an educational and training facility.

Salazar, H.; Martinez, O.; Cotzomi, J.; Moreno, E.; Aguilar, S.; Villaseñor, L.

2003-07-01

174

Pay Me Now or Pay Me Later: 10 Years Later and Have We Seen Any Change?  

ERIC Educational Resources Information Center

It has been nearly a decade since the 1996 Surgeon General?s Report (SGR) on "Physical Activity and Health" (United States Department of Health and Human Services [USDHHS], 1996). It is time that people stop and reflect on this historic report and begin the assessment process--are people paying now or will they continue to pay later? This…

Cone, Stephen L.

2004-01-01

175

Lateral interactions in the outer retina  

PubMed Central

Lateral interactions in the outer retina, particularly negative feedback from horizontal cells to cones and direct feed-forward input from horizontal cells to bipolar cells, play a number of important roles in early visual processing, such as generating center-surround receptive fields that enhance spatial discrimination. These circuits may also contribute to post-receptoral light adaptation and the generation of color opponency. In this review, we examine the contributions of horizontal cell feedback and feed-forward pathways to early visual processing. We begin by reviewing the properties of bipolar cell receptive fields, especially with respect to modulation of the bipolar receptive field surround by the ambient light level and to the contribution of horizontal cells to the surround. We then review evidence for and against three proposed mechanisms for negative feedback from horizontal cells to cones: 1) GABA release by horizontal cells, 2) ephaptic modulation of the cone pedicle membrane potential generated by currents flowing through hemigap junctions in horizontal cell dendrites, and 3) modulation of cone calcium currents (ICa) by changes in synaptic cleft proton levels. We also consider evidence for the presence of direct horizontal cell feed-forward input to bipolar cells and discuss a possible role for GABA at this synapse. We summarize proposed functions of horizontal cell feedback and feed-forward pathways. Finally, we examine the mechanisms and functions of two other forms of lateral interaction in the outer retina: negative feedback from horizontal cells to rods and positive feedback from horizontal cells to cones. PMID:22580106

Thoreson, Wallace B.; Mangel, Stuart C.

2012-01-01

176

[Lateralization of the epileptic process and psychology].  

PubMed

In a group of 70 patients with a unilateral epileptic process in the temporal limbic structures, localized in the left half of the brain in 38 patients (26 men, 12 women) and in the right half of the brain in 32 patients (17 men, 15 women) the lateralization of motor functions, asymmetry of emotional mimicry, conjugated deviation of the eye bulbs, intellect, memory, psychomotor rate and personality (laterality test of Mat?jcek--Zlab, Wechsler's intellect and memory scale, Benton, Stroop, VAROS, SUPOS, DSF, Washington Psychosocial--Seizure Inventory WPSI was investigated. Patient with a left-sided epileptic process had only insignificantly lower contact with psychiatry (31.6% as compared with 40.6%). Significantly lower contacts with psychiatry were recorded in 35 patients with a predominance of emotional mimicry (while smiling) on the left (25.0% as compared with 47.1%, p less than 0.05) and particularly significantly low in 18 patients with a combination of signs left-sided epileptic process + predominance of emotional mimicry on the left + deviation of the eyeballs on the right (mathematical stimulus) + genotypical righthandedness (16.7% as compared with 42.3%, p less than 0.025). Men with a left-sided epileptic process displayed a significantly greater anxiety, in women this trend was only indicated. Four women with a left-sided epileptic process anticipating regulation of behaviour was typical, for women with a right-sided epileptic process lower autoregulating inhibitions. A left-sided epileptic process had significantly more often a favourable course of epilepsy (in 65.8% as compared with 25.0%, p less than 0.005). In psychological tests, however, the differentiating criteria were much more than the course of the disease invalid pension, contact with psychiatry and subjective need of assistance from a psychiatrist or psychologist. PMID:2731273

Preiss, J; Kristof, M

1989-04-01

177

Quel statut pour les espaces de montagne durant l'ge du Bronze?  

E-print Network

, metallurgy, Bronze age, mountain, pastoralism, modelling. Documents d'Archéologie méridionale 28 (2005), ppQuel statut pour les espaces de montagne durant l'âge du Bronze? Regards croisés sur les approches territoire. Mots-clés: climat, territoires, anthropisation, ressources, métallurgie, âge du Bronze, milieu

Paris-Sud XI, Université de

178

Estudio de los tumores sólidos desarrollados por los ratones durante la producción de Anticuerpos Monoclonales  

Microsoft Academic Search

Los ratones constituyen un elemento fundamental para la producción de líquido ascítico rico en anticuerpos monoclonales (AcM). Durante este proceso suelen aparecer tumores sólidos que afectan directamente el volumen de producción, por lo que el objetivo de este trabajo consistió en estudiar estas neoformaciones para establecer sus características y de esta manera poder predecir las afectaciones en la producción a

Dasha Fuentes Morales; Ramiro R. González Pumarino; Bárbara O. González Navarro; Natacha Negrín

2003-01-01

179

SECTOR INDUSTRIAL COLOMBIANO Y SU EVOLUCION DURANTE EL PERIODO 1989-2009  

Microsoft Academic Search

Esta investigación se realizó con el objetivo de estudiar la dinámica del sector industrial durante los últimos veinte años a través de variables como el empleo generado, la participación en el PIB nacional y balanza comercial del sector dentro del marco económico colombiano para el periodo comprendido entre 1999 y 2009 con el fin de analizar como influenciaron en esta

FREDI GOYENECHE GONZÁLEZ; VANESSA CAROLINA BALZAN AYOLA; MARY LUZ FERNÁNDEZ RAMOS; LIZETH VANESSA MIRANDA GAVIRIA

2010-01-01

180

Variable Left-hemisphere Language and Orthographic Lateralization Reduces Right-hemisphere Face Lateralization.  

PubMed

It is commonly believed that, in right-handed individuals, words and faces are processed by distinct neural systems: one in the left hemisphere (LH) for words and the other in the right hemisphere (RH) for faces. Emerging evidence suggests, however, that hemispheric selectivity for words and for faces may not be independent of each other. One recent account suggests that words become lateralized to the LH to interact more effectively with language regions, and subsequently, as a result of competition with words for representational space, faces become lateralized to the RH. On this interactive account, left-handed individuals, who as a group show greater variability with respect to hemispheric language dominance, might be expected to show greater variability in their degree of RH lateralization of faces as well. The current study uses behavioral measures and ERPs to compare the hemispheric specialization for both words and faces in right- and left-handed adult individuals. Although both right- and left-handed groups demonstrated LH over RH superiority in discrimination accuracy for words, only the right-handed group demonstrated RH over LH advantage in discrimination accuracy for faces. Consistent with this, increased right-handedness was related to an increase in RH superiority for face processing, as measured by the strength of the N170 ERP component. Interestingly, the degree of RH behavioral superiority for face processing and the amplitude of the RH N170 for faces could be predicted by the magnitude of the N170 ERP response to words in the LH. These results are discussed in terms of a theoretical account in which the typical RH face lateralization fails to emerge in individuals with atypical language lateralization because of weakened competition from the LH representation of words. PMID:25390197

Dundas, Eva M; Plaut, David C; Behrmann, Marlene

2015-05-01

181

Lateral shift in one-dimensional quasiperiodic chiral photonic crystal  

NASA Astrophysics Data System (ADS)

We investigate the lateral shift of a one-dimensional quasiperiodic photonic crystal consisting of chiral and conventional dielectric materials. The effect of structural irregularity on lateral shift is evaluated by stationary-phase approach. Our results show that the lateral shift can be modulated by varying the structural irregularity in quasiperiodic structure. Besides, the position of peak in lateral shift spectrum stays sensitive to the chiral factor of chiral materials. In comparison with that of periodic structure, quasiperiodic structure provides an extra degree of freedom to manipulate the lateral shift.

Da, Jian; Mo, Qi; Cheng, Yaokun; Liu, Taixiang

2015-02-01

182

Direction selectivity in the middle lateral and lateral (ML and L) visual areas in the California ground squirrel  

Microsoft Academic Search

Extracellular recordings obtained from the extrastriate cortex of the California ground squirrel, a diurnal sciurid, show that large receptive fields and a strong direction selectivity are present in the middle lateral area (ML) and the lateral area (L), located laterally to V2 and V3. Direction selectivity was tested by presenting stimuli of varying dimensions, shapes and speeds at different locations

Monica Paolini; Martin I. Sereno

1998-01-01

183

Laterality Patterns of Brain Functional Connectivity: Gender Effects  

PubMed Central

Lateralization of brain connectivity may be essential for normal brain function and may be sexually dimorphic. Here, we study the laterality patterns of short-range (implicated in functional specialization) and long-range (implicated in functional integration) connectivity and the gender effects on these laterality patterns. Parallel computing was used to quantify short- and long-range functional connectivity densities in 913 healthy subjects. Short-range connectivity was rightward lateralized and most asymmetrical in areas around the lateral sulcus, whereas long-range connectivity was rightward lateralized in lateral sulcus and leftward lateralizated in inferior prefrontal cortex and angular gyrus. The posterior inferior occipital cortex was leftward lateralized (short- and long-range connectivity). Males had greater rightward lateralization of brain connectivity in superior temporal (short- and long-range), inferior frontal, and inferior occipital cortices (short-range), whereas females had greater leftward lateralization of long-range connectivity in the inferior frontal cortex. The greater lateralization of the male's brain (rightward and predominantly short-range) may underlie their greater vulnerability to disorders with disrupted brain asymmetries (schizophrenia, autism). PMID:21878483

Tomasi, Dardo; Volkow, Nora D.

2012-01-01

184

Lateral patellofemoral ligament reconstruction using a free gracilis autograft.  

PubMed

Medial patellofemoral instability is a rare, disabling condition that is often associated with the wrong indication for lateral retinacular release or overcorrection with medializing tibial tubercle osteotomy. It is an even less common complication after total knee arthroplasty (TKA). The lateral patellofemoral ligament is an important lateral stabilizer of the patella against medial subluxation or dislocation. Until now, no report in the literature has described lateral patellofemoral ligament reconstruction with a free gracilis tendon autograft. Furthermore, there has not been a single case report of lateral patellofemoral ligament reconstruction after TKA. The authors describe a novel technique for reconstruction of the lateral patellofemoral ligament in a symptomatic medial subluxated patella resulting from TKA and extended lateral release in a 62-year-old patient. The result 1 year postoperatively was deemed successful. Clinically, the patella was stable, with correct tracking, and radiologically the patella was correctly positioned. With a technique similar to that used for the medial patellofemoral ligament, the lateral patellofemoral ligament can be reconstructed with a gracilis tendon autograft to permit stabilization independent of resting scar tissue of the lateral retinaculum. This operation can be performed in a minimally invasive way, without opening the joint, therefore decreasing the risk of joint infection. The authors showed a successful clinical and radiologic outcome 1 year after lateral patellofemoral ligament reconstruction in a patient with medial patellar instability after TKA and lateral release. PMID:24992066

Borbas, Paul; Koch, Peter P; Fucentese, Sandro F

2014-07-01

185

El turismo político durante la Guerra Civil: viajeros británicos y técnicas de hospitalidad en la España republicana, 1936-1939  

Microsoft Academic Search

Este trabajo estudia uno de los principales medios de propaganda que empleó la República española para conquistar a la opinión internacional durante la Guerra Civil: los viajes organizados de personalidades extranjeras. El turismo político, a veces considerado como una peculiaridad de los regímenes socialistas, fue empleado por los dos bandos durante el conflicto, pero los republicanos lo practicaron con más

Hugo García

2006-01-01

186

Multiplex lateral flow immunoassay for mycotoxin determination.  

PubMed

A new lateral flow immunoassay (LFA) is proposed for qualitative and/or semiquantitative determination of aflatoxin B1 (AFB1), zearalenone (ZEA), deoxynivalenol (DON), and their analogues (AFs, ZEAs, DONs) in cereal samples. Each of the mycotoxin specific antibody was class specific and there was no cross reactivity to other groups of compounds. The visual limits of detection (vLOD) of the strip were 0.03, 1.6, and 10 ?g/kg for AFB1, ZEA and DON, respectively. The calculated limits of detection (cLOD) were 0.05, 1, and 3 ?g/kg, respectively. Meanwhile the cutoff values were achieved at 1, 50, and 60 ?g/kg for AFB1, ZEA and DON, respectively. Recoveries ranged from 80% to 122% and RSD from 5% to 20%. Both the vLOD and cLOD for the three mycotoxins were lower than the EU maximum levels. Analysis of naturally contaminated maize samples resulted in a good agreement between the multiplex LFA and LC-MS/MS (100% for DONs and AFs, and 81% for ZEAs). Careful analysis of the results further explained the general overestimation of LFA compared to chromatographic methods for quantification of mycotoxins. PMID:24745689

Song, Suquan; Liu, Na; Zhao, Zhiyong; Njumbe Ediage, Emmanuel; Wu, Songling; Sun, Changpo; De Saeger, Sarah; Wu, Aibo

2014-05-20

187

Risk factors for amyotrophic lateral sclerosis  

PubMed Central

Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease. It is typically fatal within 2–5 years of symptom onset. The incidence of ALS is largely uniform across most parts of the world, but an increasing ALS incidence during the last decades has been suggested. Although recent genetic studies have substantially improved our understanding of the causes of ALS, especially familial ALS, an important role of non-genetic factors in ALS is recognized and needs further study. In this review, we briefly discuss several major genetic contributors to ALS identified to date, followed by a more focused discussion on the most commonly examined non-genetic risk factors for ALS. We first review factors related to lifestyle choices, including smoking, intake of antioxidants, physical fitness, body mass index, and physical exercise, followed by factors related to occupational and environmental exposures, including electromagnetic fields, metals, pesticides, ?-methylamino-L-alanine, and viral infection. Potential links between ALS and other medical conditions, including head trauma, metabolic diseases, cancer, and inflammatory diseases, are also discussed. Finally, we outline several future directions aiming to more efficiently examine the role of non-genetic risk factors in ALS. PMID:25709501

Ingre, Caroline; Roos, Per M; Piehl, Fredrik; Kamel, Freya; Fang, Fang

2015-01-01

188

Laterally graded multilayer double-monochromator.  

SciTech Connect

The authors describe a tunable multilayer monochromator with an adjustable bandpass to be used for reflectivity and grazing incidence diffraction studies on surfaces at energies near 10 keV. Multilayers have a bandpass typically 100 times larger than the Si(111) reflection, and by using multilayers an experimenter can significantly increase data collection rates over those available with a Si monochromator. The transmission through 1 and 2 laterally graded multilayer (LGML) reflections was recorded versus photon energy. The identical LGMLs were comprised of 60 bilayers of W and C on 100 x 25 x 3 mm float glass with a bilayer spacing varying from 35 to 60 {angstrom}. The average gradient was 0.27 {angstrom}/mm along the long dimension. The rms deviation of the data for the bilayer spacing from a linear fit was 0.36 {angstrom}. Data were obtained for a nondispersive ({+-}) double-multilayer arrangement. The relative bandpass width (FWHM) when the two multilayers exposed the same bilayer spacing was measured to be 2.2% with a transmission of 78.7 {+-} 1.6%. This value is consistent with the transmission of 88.9% that they also measured for a single LGML at HASYLAB beamline D4. The bandpass was tunable in the range 1.1% to 2.2%.

Als-Nielsen, J.; Erdmann, J.; Gaarde, P.; Krasnicki, S.; Liu, C.; Macrander, A. T.; Maj, J.; Mancini, D.

1999-09-01

189

Chromogranin peptides in amyotrophic lateral sclerosis.  

PubMed

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder which primarily affects motor neurons. Eight cases of ALS and seven control cases were studied with semiquantitative immunocytochemistry for chromogranin A, chromogranin B and secretogranin II that are soluble constituents of large dense core vesicles, synaptophysin as a membrane protein of small synaptic vesicles and superoxide dismutase 1. Among the chromogranin peptides, the number and staining intensity of motor neurons was highest for chromogranin A. In ALS, the staining intensity for chromogranin peptides and synaptophysin was significantly lower in the ventral horn of ALS patients due to a loss in immunoreactive motor neurons, varicose fibers and varicosities. For all chromogranins, the remaining motor neurons displayed a characteristic staining pattern consisting of an intracellular accumulation of immunoreactivity with a high staining intensity. Confocal microscopy of motor neurons revealed that superoxide dismutase 1-immunopositive intracellular aggregates also contained chromogranin A, chromogranin B and secretogranin II. These findings indicate that there is a loss of small and large dense core vesicles in presynaptic terminals. The intracellular co-occurrence of superoxide dismutase 1 and chromogranins may suggest a functional interaction between these proteins. This study should prompt further experiments to elucidate the role of chromogranins in ALS patients. PMID:18721831

Schrott-Fischer, A; Bitsche, M; Humpel, C; Walcher, C; Maier, H; Jellinger, K; Rabl, W; Glueckert, R; Marksteiner, J

2009-01-01

190

Early environment influences later performance in fishes.  

PubMed

Conditions fish encounter during embryogenesis and early life history can leave lasting effects not only on morphology, but also on growth rate, life-history and behavioural traits. The ecology of offspring can be affected by conditions experienced by their parents and mother in particular. This review summarizes such early impacts and their ecological influences for a variety of teleost species, but with special reference to salmonids. Growth and adult body size, sex ratio, egg size, lifespan and tendency to migrate can all be affected by early influences. Mechanisms behind such phenotypically plastic impacts are not well known, but epigenetic change appears to be one central mechanism. The thermal regime during development and incubation is particularly important, but also early food consumption and intraspecific density can all be responsible for later life-history variation. For behavioural traits, early experiences with effects on brain, sensory development and cognition appear essential. This may also influence boldness and other social behaviours such as mate choice. At the end of the review, several issues and questions for future studies are given. PMID:24961386

Jonsson, B; Jonsson, N

2014-08-01

191

Treatment algorithm for chronic lateral ankle instability  

PubMed Central

Summary Introduction: ankle sprains are a common sports-related injury. A 20% of acute ankle sprains results in chronic ankle instability, requiring surgery. Aim of this paper is to report the results of a series of 38 patients treated for chronic lateral ankle instability with anatomic reconstruction. Materials and methods: thirty-eight patients were enrolled in the study. Seventeen patients underwent a surgical repair using the Brostrom-modified technique, while the remaining underwent anatomic reconstruction with autologous or allogenic graft. Results: at a mean follow-up of 5 years the AOFAS score improved from 66.1 ± 5.3 to 92.2 ± 5.6. Discussion: the findings of this study confirm that anatomic reconstruction is an effective procedure with satisfactory subjective and objective results which persist at long-term follow-up along with a low complication rate. No differences, in term of clinical and functional outcomes, were observed between the Brostrom-modified repair and the anatomic reconstruction technique. Level of evidence: level IV. PMID:25767783

Giannini, Sandro; Ruffilli, Alberto; Pagliazzi, Gherardo; Mazzotti, Antonio; Evangelisti, Giulia; Buda, Roberto; Faldini, Cesare

2014-01-01

192

Lateral gene transfer in the subsurface  

SciTech Connect

Lateral gene transfer (LGT) is an important adaptive mechanism among prokaryotic organisms. This mechanism is particularly important for the response of microorganisms to changing environmental conditions because it facilitates the transfer of a large number of genes and their rapid expression. Together the transferred genes promote rapid genetic and metabolic changes that may enhance survival to newly established and sometimes hostile environmental conditions. The goal of our project was to examine if and how LGT enhances microbial adaptation to toxic heavy metals in subsurface environments that had been contaminated by mixed wastes due to activities associated with the production of nuclear energy and weapons. This task has been accomplished by dividing the project to several sub-tasks. Thus, we: (1) Determined the level of resistance of subsurface bacterial isolates to several toxic metals, all identified as pollutants of concern in subsurface environments; (2) Designed, tested, and applied, a molecular approach that determined whether metal resistance genes had evolved by LGT among subsurface bacteria; and (3) Developed a DNA hybridization array for the identification of broad host range plasmids and of metal resistance plasmids. The results are briefly summarized below with references to published papers and manuscripts in preparation where details about our research can be found. Additional information may be found in copies of our published manuscripts and conference proceedings, and our yearly reports that were submitted through the RIMS system.

Barkay, Tamar; Sobecky, Patricia

2007-08-27

193

Mitochondrial Dysfunction in Amyotrophic Lateral Sclerosis  

PubMed Central

The etiology of motor neuron degeneration in amyotrophic lateral sclerosis (ALS) remains to be better understood. Based on the studies from ALS patients and transgenic animal models, it is believed that ALS is likely to be a multifactorial and multisystem disease. Many mechanisms have been postulated to be involved in the pathology of ALS, such as oxidative stress, glutamate excitotoxicity, mitochondrial damage, defective axonal transport, glia cell pathology and aberrant RNA metabolism. Mitochondria, which play crucial roles in excitotoxicity, apoptosis and cell survival, have shown to be an early target in ALS pathogenesis and contribute to the disease progression. Morphological and functional defects in mitochondria were found in both human patients and ALS mice overexpressing mutant SOD1. Mutant SOD1 was found to be preferentially associated with mitochondria and subsequently impair mitochondrial function. Recent studies suggest that axonal transport of mitochondria along microtubules and mitochondrial dynamics may also be disrupted in ALS. These results also illustrate the critical importance of maintaining proper mitochondrial function in axons and neuromuscular junctions, supporting the emerging “dying-back” axonopathy model of ALS. In this review, we will discuss how mitochondrial dysfunction has been linked to the ALS variants of SOD1 and the mechanisms by which mitochondrial damage contributes to the disease etiology. PMID:19715760

Shi, Ping; Gal, Jozsef; Kwinter, David M.; Liu, Xiaoyan; Zhu, Haining

2009-01-01

194

Does cerebral lateralization develop? A study using functional transcranial Doppler ultrasound assessing lateralization for language production and visuospatial memory  

PubMed Central

In the majority of people, language production is lateralized to the left cerebral hemisphere and visuospatial skills to the right. However, questions remain as to when, how, and why humans arrive at this division of labor. In this study, we assessed cerebral lateralization for language production and for visuospatial memory using functional transcranial Doppler ultrasound in a group of 60 typically developing children between the ages of six and 16 years. The typical pattern of left-lateralized activation for language production and right-lateralized activation for visuospatial memory was found in the majority of the children (58%). No age-related change in direction or strength of lateralization was found for language production. In contrast, the strength of lateralization (independent of direction) for visuospatial memory function continued to increase with age. In addition, boys showed a trend for stronger right-hemisphere lateralization for visuospatial memory than girls, but there was no gender effect on language laterality. We tested whether having language and visuospatial functions in the same hemisphere was associated with poor cognitive performance and found no evidence for this “functional crowding” hypothesis. We did, however, find that children with left-lateralized language production had higher vocabulary and nonword reading age-adjusted standard scores than other children, regardless of the laterality of visuospatial memory. Thus, a link between language function and left-hemisphere lateralization exists, and cannot be explained in terms of maturational change. PMID:22741100

Groen, Margriet A; Whitehouse, Andrew J O; Badcock, Nicholas A; Bishop, Dorothy V M

2012-01-01

195

Determination of lateral-stability derivatives and transfer-function coefficients from frequency-response data for lateral motions  

NASA Technical Reports Server (NTRS)

A method is presented for determining the lateral-stability derivatives, transfer-function coefficients, and the modes for lateral motion from frequency-response data for a rigid aircraft. The method is based on the application of the vector technique to the equations of lateral motion, so that the three equations of lateral motion can be separated into six equations. The method of least squares is then applied to the data for each of these equations to yield the coefficients of the equations of lateral motion from which the lateral-stability derivatives and lateral transfer-function coefficients are computed. Two numerical examples are given to demonstrate the use of the method.

Donegan, James J; Robinson, Samuel W , Jr; Gates, Ordway, B , jr

1955-01-01

196

Venous thromboembolism in amyotrophic lateral sclerosis  

PubMed Central

Objective: To prospectively assess the incidence of both symptomatic and asymptomatic venous thromboembolism (VTE) in patients with amyotrophic lateral sclerosis (ALS) and to identify risk factors. Methods: Fifty outpatients with ALS were recruited consecutively and prospectively evaluated with bilateral venous duplex ultrasonography (VDU) of the proximal leg veins at enrollment and 6 and 12 months. The primary outcome measure was clinically important VTE, defined as asymptomatic proximal deep vein thrombosis (DVT) by screening VDU, symptomatically proven DVT or pulmonary embolism (PE), or fatal PE. For each patient, person-days of follow-up were recorded from enrollment until the date of VTE, death, loss to follow-up, or final 12-month visit. Results: During the 1-year follow-up period, VTE was detected in 4 patients (1 symptomatic DVT, 1 symptomatic PE, and 2 asymptomatic DVTs) over 13,011 person-days of follow-up, representing an 11.2% 1-year incidence. Subjects with leg-onset ALS or significant leg weakness had a 1-year VTE incidence rate of 35.8% and 35.5%, respectively. VTE risk was significantly increased for those patients with decreased lower extremity Revised ALS Functional Rating Scale subscore (p = 0.03), decreased Lower Extremity Activity Scale score (p = 0.02), and decreased average lower limb Medical Research Council scale strength score (p = 0.03). Conclusions: Our data suggest that clinically important VTE is common in patients with ALS, particularly those with leg weakness and reduced mobility. Given these results, the potential benefits of routine VTE screening and primary prophylaxis in high-risk patients with ALS with leg weakness should be explored in future studies. In the meantime, physicians should have a low threshold for considering VTE in patients with ALS with leg weakness. PMID:24727309

Gladman, Matthew; DeHaan, Melanie; Pinto, Hanika; Geerts, William

2014-01-01

197

Lateral Shock of the R Aquarii Jet  

NASA Technical Reports Server (NTRS)

The R Aqr jet was observed with the VLA B-configuration at two epochs separated by approximately 13.2 yr. Comparison of the resulting 6 cm continuum images show that the radio jet has undergone a lateral counterclockwise rotation of approximately 6 deg-12 deg on the plane of the sky. The model of jet parcels on independent trajectories is difficult to reconcile with these observations and leads us to consider a path-oriented jet (i.e., younger parcels follow the same path as older parcels). Comparison of the most recent radio image with a nearly contemporaneous HST/FOC ultraviolet image at approximately 2330 Angstroms suggests that the ultraviolet emission lies along the leading side of the rotating radio jet. In conjunction with a proper motion analysis of the jet material that yields empirical space-velocity and resulting acceleration-magnitude relationships as a function of distance from the central source, we evaluate the observational results in terms of a schematic model in which the jet emission consists of plane-parallel isothermal shocks along the leading edge of rotation. In such a radiating shock, the ultraviolet-emitting region is consistent with the adiabatic region in the form of a high-temperature, low-density sheath that surrounds the cooled postshock radio-emitting region. Within the context of the schematic model, we obtain the temperatures, densities, and pressures within the preshock, adiabatic, and postshock regions as a function of distance from the central source; the physical parameters so derived compare favorably to previously published estimates. We obtain a total jet mass of 3.1 x 10(exp -5) solar mass and an age of approximately 115 yr. We evaluate the model in the context of its density-boundary condition, its applicability to an episodic or quasi-continuous jet, and angular momentum considerations.

Hollis, J. M.; Pedelty, J. A.; Kafatos, M.

1997-01-01

198

Measuring lateral shuffle and side cut performance.  

PubMed

Lateral shuffle and side cut (SSC) movements are defensive basketball movements where movement speed is critical to performance. The purpose of this study was to compare SSC data obtained using timing lights with motion capture system data and to determine the most appropriate method for measuring SSC performance. Shuffle time data were recorded using both timing lights and a motion capture system while 9 male subjects performed 2 different SSC movement sets, with and without controlling for arm movements, which may influence performance times. Shuffle and side cut times and SSC displacements were used to calculate mean shuffle velocity for each trial. The SEs for the motion capture system were estimated for SSC times (± 4.2 milliseconds; ~0.24% of mean shuffle time) and velocities (± 5.5 mm · s; ~0.24% of mean shuffle velocity), respectively, indicating high levels of precision. Timing light movement time variability was significantly higher during the uncontrolled (SD = 42 milliseconds) when compared with the controlled (SD = 9 milliseconds, p < 0.001) condition, indicating a significant reduction in variability by controlling non-performance-related variability such as arm movement. A significant positive correlation was found between SSC time and SSC displacement (r = 0.42) indicating that performance times were dependent on displacement. Furthermore, the variance in motion-captured SSC velocity was significantly smaller than the variance in velocity determined using timing lights (p < 0.05). We concluded that motion-captured SSC velocity data reduced systematic errors and non-performance-related movement variability and, therefore, was better able to reflect true performance. As true performance variability in human movement provides important information, the presented method for calculating SSC velocity in this study is recommended for assessing SSC performance. PMID:23439340

Whitting, John W; de Melker Worms, Jonathan L A; Maurer, Christian; Nigg, Sandro R; Nigg, Benno M

2013-11-01

199

Efferent connections of the lateral cortex of the lizard Gekko gecko: evidence for separate origins of medial and lateral pathways from the lateral cortex to the hypothalamus.  

PubMed

The lateral cortex of the lizard Gekko gecko is composed of three parts: a dorsal and ventral part located rostrally and a posterior part located caudally. In order to obtain detailed information about the efferent connections of these lateral cortex subdivisions, iontophoretic injections of the anterograde tracers Phaseolus vulgaris leucoagglutinin and biotinylated dextran were made in the various parts. The main projection from the dorsal part terminates in the caudal part of the medial cortex. Other cortical projections were noted to the ipsi- and contralateral lateral cortex, the large-celled part of the medial cortex, and the dorsal cortex. Additional fibers were found bilaterally in the anterior olfactory nucleus and the external amygdaloid nucleus. The ventral part of the lateral cortex projects mainly to the ipsilateral, posterior part of the dorsal ventricular ridge and the external amygdaloid nucleus. Minor contralateral projections to these nuclei were also found. Other projections were observed to travel to the caudal part of the medial cortex, to the nucleus sphericus, and bilaterally to the lateral cortex and the anterior olfactory nucleus. The posterior part of the lateral cortex has similar efferent connections as the dorsal part and should be regarded as the caudal continuation of the dorsal part. Because previous studies have shown that the medial cortex and the amygdaloid complex project to different hypothalamic areas, we conclude that the dorsal and ventral parts of the lateral cortex transmit olfactory information to separate hypothalamic areas that are probably involved with different types of behavior. PMID:7535810

Hoogland, P V; Vermeulen-Vanderzee, E

1995-02-13

200

Lateral position detection and control for friction stir systems  

DOEpatents

Friction stir methods are disclosed for processing at least one workpiece using a rotary tool with rotating member for contacting and processing the workpiece. The methods include oscillating the rotary tool laterally with respect to a selected propagation path for the rotating member with respect to the workpiece to define an oscillation path for the rotating member. The methods further include obtaining force signals or parameters related to the force experienced by the rotary tool at least while the rotating member is disposed at the extremes of the oscillation. The force signals or parameters associated with the extremes can then be analyzed to determine a lateral position of the selected path with respect to a target path and a lateral offset value can be determined based on the lateral position. The lateral distance between the selected path and the target path can be decreased based on the lateral offset value.

Fleming, Paul (Boulder, CO); Lammlein, David H. (Houston, TX); Cook, George E. (Brentwood, TN); Wilkes, Don Mitchell (Nashville, TN); Strauss, Alvin M. (Nashville, TN); Delapp, David R. (Ashland City, TN); Hartman, Daniel A. (Fairhope, AL)

2011-11-08

201

Lateral position detection and control for friction stir systems  

DOEpatents

An apparatus and computer program are disclosed for processing at least one workpiece using a rotary tool with rotating member for contacting and processing the workpiece. The methods include oscillating the rotary tool laterally with respect to a selected propagation path for the rotating member with respect to the workpiece to define an oscillation path for the rotating member. The methods further include obtaining force signals or parameters related to the force experienced by the rotary tool at least while the rotating member is disposed at the extremes of the oscillation. The force signals or parameters associated with the extremes can then be analyzed to determine a lateral position of the selected path with respect to a target path and a lateral offset value can be determined based on the lateral position. The lateral distance between the selected path and the target path can be decreased based on the lateral offset value.

Fleming, Paul; Lammlein, David H.; Cook, George E.; Wilkes, Don Mitchell; Strauss, Alvin M.; Delapp, David R.; Hartman, Daniel A.

2012-06-05

202

Artificial lateral line with biomimetic neuromasts to emulate fish sensing.  

PubMed

Hydrodynamic imaging using the lateral line plays a critical role in fish behavior. To engineer such a biologically inspired sensing system, we developed an artificial lateral line using MEMS (microelectromechanical system) technology and explored its localization capability. Arrays of biomimetic neuromasts constituted an artificial lateral line wrapped around a cylinder. A beamforming algorithm further enabled the artificial lateral line to image real-world hydrodynamic events in a 3D domain. We demonstrate that the artificial lateral line system can accurately localize an artificial dipole source and a natural tail-flicking crayfish under various conditions. The artificial lateral line provides a new sense to man-made underwater vehicles and marine robots so that they can sense like fish. PMID:20061601

Yang, Yingchen; Nguyen, Nam; Chen, Nannan; Lockwood, Michael; Tucker, Craig; Hu, Huan; Bleckmann, Horst; Liu, Chang; Jones, Douglas L

2010-03-01

203

Non-destructive Characterizing of Lateral Doping Effects  

NASA Astrophysics Data System (ADS)

As channel lengths decrease, device performance becomes increasingly sensitive to lateral doping effects. We report on methods of non-contact measurement of lateral diffusion and implant straggle using a combination of a bar mask pattern and Carrier Illumination™ measurements, in which one laser beam generates excess carriers and a second laser beam reflects from the excess carrier distribution. Doped region width is extracted from measurements in structures with a range of pitches and fills from 0 to 100%. The method may be applied to both pre- and post-annealed structures, with orthogonal bar patterns used to determine the vector components of lateral doping. Lateral resolution of 0.5 nm is demonstrated. Both vertical and lateral diffusion distance are obtained. Data presented shows that the ratio of lateral to vertical diffusion depends on implant and anneal conditions. Measurements of high-current single-wafer implants show implant angle uniformity of better than ±1°.

Borden, P.; Budiarto, E.; Felch, S.; Graoui, H.

2005-09-01

204

Treball femení a la indústria tèxtil llanera de Sabadell durant el segle XX  

Microsoft Academic Search

El tema de la tesi és el treball femení a la indústria tèxtil llanera sabadellenca durant el\\u000asegle XX. S'ha elaborat des de l'antropologia històrica, amb influències de la història local, la\\u000ageografia humana i la història econòmica. L'objectiu principal era analitzar el treball de les\\u000adones, conèixer quins oficis desenvolupaven, en quines condicions, quin era el seu nivell formatiu,

Virginia Domínguez Álvarez

2008-01-01

205

Propriedades de estruturas temporais rápidas submilimétricas durante uma grande explosão solar  

NASA Astrophysics Data System (ADS)

Apresentamos novas propriedades de variações rápidas da emissão submilimétrica durante uma das maiores explosões solares do ciclo solar 23. Os dados analisados neste estudo foram obtidos com o Telescópio Solar Submilimétrico (SST), que observa o Sol em 212 GHz e 405 GHz, e comparados com emissões em Raios-X duros e Raios-gama (fótons de energia > 10 MeV), que foram obtidas pelo experimento GRS do Yohkoh. Aplicamos diferentes metodologias para detectar e caracterizar, ao longo do evento, os pulsos submilimétricos (duração de 50-300 ms) detectados acima de uma componente mais lenta (alguns minutos). Os resultados mostram que durante a fase impulsiva, num instante próximo ao tempo do máximo do evento, houve um aumento da ocorrência de maiores e de mais rápidas estruturas temporais. Também identificamos uma boa correlação com as emissões em raios-X e raios-gama (até a faixa de energia 10-100 MeV), indicando que os pulsos rápidos submilimétricos refletiram injeções primárias de energia durante o evento.O espectro do fluxo desses pulsos é crescente com a freqüência entre 212 and 405 GHz, na maioria dos casos, ao contrário do observado para a componente gradual. As posições calculadas para as estruturas rápidas são discretas, compactas e localizadas em toda a área da região ativa, o que é previsto nos modelos de explosões solares decorrentes de instabilidades múltiplas em diferentes pequenas regiões. Por outro lado, a posição calculada para a componente lenta é estável durante a fase impulsiva. Assim, a comparação entre as características do espectro de fluxo e da localização da emissão, para os pulsos rápidos e para a componente gradual, sugere que as respectivas emissões são de natureza diferente.

Raulin, J.-P.; Kaufmann, P.; Gimenez de Castro, C. G.; Pacini, A. A.; Makhmutov, V.; Levato, H.; Rovira, M.

2003-08-01

206

Modified obtuse-angled lateral exposure of the calcaneum  

Microsoft Academic Search

Objective: The objective of this study is to compare the incidence of post-operative skin healing problems between the classic extensile lateral calcaneal approach and a modified obtuse-angle lateral exposure during the period 1994–2003.Methods: The classic extensile lateral calcaneal approach as described in the literature was (used in 55 cases of calcaneal fractures), while the obtuse-angled approach (used in other 39

Tarek Hussain; Husain Al-Mutairi; Sabrine Al-Zamel; Waleed Al-Tunaib

2004-01-01

207

Development of the lateral line system in the shovelnose sturgeon.  

PubMed

The lateral line systems of aquatic amphibians and all chondrichthyan and osteichthyan fish present a similar array of mechanoreceptors. However, electroreceptors, the second major component of the lateral line system, have clearly undergone more significant evolutionary change. Chondrichthyans and non-neopterygian fish possess primitive ampullary organ electroreceptors, whereas significantly different 'new' ampullary organs and tuberous electroreceptors are found in a few groups of teleosts (mormyrids, gymnotids and some catfish). The pairing of mechano- and electroreceptors in the lateral line system, as well as the morphologically and physiologically distinct electroreceptors of teleosts have inspired several recent studies on the origin and evolution of the lateral line receptors. We described the development of the lateral line system in sturgeon (Scaphirhynchus platorynchus) as part of an outgroup analysis of lateral line development in three taxa: vertebrates that have both mechanoreceptive neuromasts and primitive electroreceptors; neopterygian fish that only have mechanoreceptors; and teleosts that have re-evolved new electroreceptors. Development in Scaphirhynchus was consistent with previously studied taxa in that the lateral line system developed from a series of six dorsolateral placodes. Interestingly, we found that the octaval placode was bound rostrally and caudally by large placodal fields, out of which the six lateral line placodes arose. This finding supports recent suggestions for a common placodal primordium for all placodes. Each of the six placodes gave rise to the lateral line nerves before elongating into sensory ridges, which contained neuromast primordia. The ampullary organ fields of Scaphirhynchus arose from the lateral zones of the anterodorsal, anteroventral, otic and supratemporal sensory ridges, which is also consistent with recently studied taxa. Comparisons of the lateral line system of Scaphirhynchus and close relatives, Acipenser and Polyodon, indicate that variation in some aspects of lateral line receptor numbers and distribution are related to changes in head morphology and feeding strategy, whereas other changes, such as a reduction in receptor number without a change in placode field size, indicate changes in placode development. PMID:15205543

Gibbs, Melissa A; Northcutt, R Glenn

2004-01-01

208

7. SEGMENT OF LATERAL WITH YUCCA ALONG BANKS, SOUTH OF ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. SEGMENT OF LATERAL WITH YUCCA ALONG BANKS, SOUTH OF 6TH AVENUE (SECTION 10). - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

209

4. SEGMENT OF LATERAL WEST OF C STREET (SECTION 10) ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. SEGMENT OF LATERAL WEST OF C STREET (SECTION 10) ON THE ROCKY MOUNTAIN ARSENAL (RMA). - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

210

24. CULVERT WITH CONCRETE HEADWALL AND SIDEWALLS CARRYING THE LATERAL ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

24. CULVERT WITH CONCRETE HEADWALL AND SIDEWALLS CARRYING THE LATERAL UNDER 8TH AVENUE. - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

211

2. COURSE OF THE LATERAL THROUGH DEL NORTHWEST MAR PARK. ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. COURSE OF THE LATERAL THROUGH DEL NORTHWEST MAR PARK. - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

212

13. TREES ALONG LATERAL SEGMENT AT THE NORTHERN END OF ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

13. TREES ALONG LATERAL SEGMENT AT THE NORTHERN END OF LAKE LADORA. - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

213

8. GENERAL VIEW OF LARGE DIVERSION STRUCTURE ON LATERAL WEST ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. GENERAL VIEW OF LARGE DIVERSION STRUCTURE ON LATERAL WEST OF LOWER DERBY LAKE (SECTION 2). - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

214

The lateral plate mesoderm: a novel source of skeletal muscle.  

PubMed

It has been established in the last century that the skeletal muscle cells of vertebrates originate from the paraxial mesoderm. However, recently the lateral plate mesoderm has been identified as a novel source of the skeletal muscle. The branchiomeric muscles, such as masticatory and facial muscles, receive muscle progenitor cells from both the cranial paraxial mesoderm and lateral plate mesoderm. At the occipital level, the lateral plate mesoderm is the sole source of the muscle progenitors of the dorsolateral neck muscle, such as trapezius and sternocleidomastoideus in mammals and cucullaris in birds. The lateral plate mesoderm requires a longer time for generating skeletal muscle cells than the somites. The myogenesis of the lateral plate is determined early, but not cell autonomously and requires local signals. Lateral plate myogenesis is regulated by mechanisms controlling the cranial myogenesis. The connective tissue of the lateral plate-derived muscle is formed by the cranial neural crest. Although the cranial neural crest cells do not control the early myogenesis, they regulate the patterning of the branchiomeric muscles and the cucullaris muscle. Although satellite cells derived from the cranial lateral plate show distinct properties from those of the trunk, they can respond to local signals and generate myofibers for injured muscles in the limbs. In this review, we key feature in detail the muscle forming properties of the lateral plate mesoderm and propose models of how the myogenic fate may have arisen. PMID:25344670

Pu, Qin; Patel, Ketan; Huang, Ruijin

2015-01-01

215

The split peroneus longus lateral ankle stabilization procedure.  

PubMed

The authors present an interesting approach to lateral ankle stabilization using the peroneus longus tendon. The more commonly utilized procedures for instability of the ankle complex, rationale for use of the peroneus longus tendon, and the details of the split peroneus longus lateral ankle stabilization procedure are presented. When evaluating patients with lateral ankle joint instability, the subtalar joint (STJ) complex needs to be assessed. In addition, the role of STJ instability and its relationship to lateral ankle joint instability are discussed. PMID:8081340

Yu, G V; Lynn, J A; Thornton, D; Choos, J N

1994-01-01

216

Lateral patellotibial ligament reconstruction for medial patellar instability.  

PubMed

Medial patellar instability, though infrequently recognized, can be a disabling complication of a lateral retinacular release. Patients with persistent anterior knee pain and instability after lateral release should be evaluated closely. If evidence of increased medial patellar translation is identified on physical examination, a trial of reverse McConnell taping should be prescribed. If there is noted improvement in symptoms after this taping trial, reconstruction of the lateral patellotibial ligament should be considered. This article details our technique for lateral patellotibial ligament reconstruction using iliotibial band and patellar tendon autografts. PMID:25473603

Sawyer, Gregory A; Cram, Tyler; LaPrade, Robert F

2014-10-01

217

Lateral Patellotibial Ligament Reconstruction for Medial Patellar Instability  

PubMed Central

Medial patellar instability, though infrequently recognized, can be a disabling complication of a lateral retinacular release. Patients with persistent anterior knee pain and instability after lateral release should be evaluated closely. If evidence of increased medial patellar translation is identified on physical examination, a trial of reverse McConnell taping should be prescribed. If there is noted improvement in symptoms after this taping trial, reconstruction of the lateral patellotibial ligament should be considered. This article details our technique for lateral patellotibial ligament reconstruction using iliotibial band and patellar tendon autografts. PMID:25473603

Sawyer, Gregory A.; Cram, Tyler; LaPrade, Robert F.

2014-01-01

218

Lateral Patellofemoral Ligament Reconstruction Using a Quadriceps Tendon Graft.  

PubMed

Medial patellar subluxation (MPS) is normally described after a lateral retinacular release. However, isolated MPS in the absence of a previous lateral release does occur. This type of patellar instability is often overlooked, and a high index of suspicion is needed for appropriate diagnosis and treatment. This report describes a technique developed in response to episodes of isolated MPS. The technique uses a partial-thickness graft from the quadriceps tendon to reconstruct the lateral patellofemoral ligament and provide stability to the lateral side of the patella. PMID:25264506

Saper, Michael G; Shneider, David A

2014-08-01

219

23. VIEW SHOWING SALT RIVER PROJECT CREWS SLIPFORMING LATERAL DURING ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

23. VIEW SHOWING SALT RIVER PROJECT CREWS SLIPFORMING LATERAL DURING REHABILITATION AND BETTERMENT PROGRAM Photographer: unknown. April 1968 - Arizona Canal, North of Salt River, Phoenix, Maricopa County, AZ

220

FILM OPTION CURRICULUM (FOR STUDENTS ENTERING FALL, 2011 OR LATER)  

E-print Network

FILM OPTION CURRICULUM (FOR STUDENTS ENTERING FALL, 2011 OR LATER) NOTE ON REVERSE. GATE REQUIREMENTS FOR FILM OPTION: FILM 100IH ­ Introduction to Film & Photography ...................................................................... 3

Lawrence, Rick L.

221

Gene for a protein capable of enhancing lateral root formation.  

PubMed

Analysis of genes preferentially expressed in hairy roots caused by infection with Agrobacterium rhizogenes has provided insights into the regulation of lateral root formation. A hairy root preferential cDNA, HR7, has been cloned from hairy roots of Hyoscyamus niger. HR7 encodes a novel protein partially homologous to a metallocarboxypeptidase inhibitor and is expressed exclusively in the primordium and base of lateral roots in hairy roots. Overexpression of HR7 in transgenic roots of H. niger dramatically enhances the frequency of lateral root formation. The results of this study indicate that expression of HR7 plays a critical role in initiating lateral root formation. PMID:10356981

Mikami, Y; Horiike, G; Kuroyanagi, M; Noguchi, H; Shimizu, M; Niwa, Y; Kobayashi, H

1999-05-14

222

Serotonergic mechanisms in amyotrophic lateral sclerosis.  

PubMed

Serotonin (5-HT) has been intimately linked with global regulation of motor behavior, local control of motoneuron excitability, functional recovery of spinal motoneurons as well as neuronal maturation and aging. Selective degeneration of motoneurons is the pathological hallmark of amyotrophic lateral sclerosis (ALS). Motoneurons that are preferentially affected in ALS are also densely innervated by 5-HT neurons (e.g., trigeminal, facial, ambiguus, and hypoglossal brainstem nuclei as well as ventral horn and motor cortex). Conversely, motoneuron groups that appear more resistant to the process of neurodegeneration in ALS (e.g., oculomotor, trochlear, and abducens nuclei) as well as the cerebellum receive only sparse 5-HT input. The glutamate excitotoxicity theory maintains that in ALS degeneration of motoneurons is caused by excessive glutamate neurotransmission, which is neurotoxic. Because of its facilitatory effects on glutaminergic motoneuron excitation, 5-HT may be pivotal to the pathogenesis and therapy of ALS. 5-HT levels as well as the concentrations 5-hydroxyindole acetic acid (5-HIAA), the major metabolite of 5-HT, are reduced in postmortem spinal cord tissue of ALS patients indicating decreased 5-HT release. Furthermore, cerebrospinal fluid levels of tryptophan, a precursor of 5-HT, are decreased in patients with ALS and plasma concentrations of tryptophan are also decreased with the lowest levels found in the most severely affected patients. In ALS progressive degeneration of 5-HT neurons would result in a compensatory increase in glutamate excitation of motoneurons. Additionally, because 5-HT, acting through presynaptic 5-HT1B receptors, inhibits glutamatergic synaptic transmission, lowered 5-HT activity would lead to increased synaptic glutamate release. Furthermore, 5-HT is a precursor of melatonin, which inhibits glutamate release and glutamate-induced neurotoxicity. Thus, progressive degeneration of 5-HT neurons affecting motoneuron activity constitutes the prime mover of the disease and its progression and treatment of ALS needs to be focused primarily on boosting 5-HT functions (e.g., pharmacologically via its precursors, reuptake inhibitors, selective 5-HT1A receptor agonists/5-HT2 receptor antagonists, and electrically through transcranial administration of AC pulsed picotesla electromagnetic fields) to prevent excessive glutamate activity in the motoneurons. In fact, 5HT1A and 5HT2 receptor agonists have been shown to prevent glutamate-induced neurotoxicity in primary cortical cell cultures and the 5-HT precursor 5-hydroxytryptophan (5-HTP) improved locomotor function and survival of transgenic SOD1 G93A mice, an animal model of ALS. PMID:16861147

Sandyk, Reuven

2006-07-01

223

Enhanced performance of methamphetamine lateral flow cassettes using an electronic lateral flow reader.  

PubMed

Surface contamination from methamphetamine in meth labs continues to be a problem. We had previously developed a lateral flow assay cassette for field detection of methamphetamine contamination that is commercially available and has been used by a number of groups to assess contamination. This cassette uses the complete disappearance of the test line as an end point for detection of 50 ng/100 cm2 of methamphetamine contamination for surface sampling with cotton swabs. In the present study, we further evaluate the response of the cassettes using an electronic lateral flow reader to measure the intensities of the test and control lines. The cassettes were capable of detecting 0.25 ng/ml for calibration solutions. For 100 cm2 ceramic tiles that were spiked with methamphetamine and wiped with cotton-tipped wooden swabs wetted in assay/sampling buffer, 1 ng/tile was detected using the reader. Semi-quantitative results can be produced over the range 0-10 ng/ml for calibration solutions and 0-25 ng/tile for spiked tiles using either a 4-parameter logistic fit of test line intensity versus concentration or spiked mass or the ratio of the control line to the test line intensity fit to concentration or spiked mass. Recovery from the tiles was determined to be about 30% using the fitted curves. Comparison of the control line to the test line was also examined as a possible visual detection end point and it was found that the control line became more intense than the test line at 0.5 to 1 ng/ml for calibration solutions or 1 to 2 ng/tile for spiked tiles. Thus the lateral flow cassettes for methamphetamine have the potential to produce more sensitive semi-quantitative results if an electronic lateral flow reader is used and can be more sensitive for detection if the comparison of the control line to the test line is used as the visual end point. PMID:25379615

Smith, Jerome P; Sammons, Deborah L; Robertson, Shirley A; Snawder, John E

2015-01-01

224

Atomically flat diamond (111) surface formation by homoepitaxial lateral growth  

Microsoft Academic Search

A process of homoepitaxial growth of diamond (111) films by microwave plasma-enhanced chemical vapor deposition has been investigated characterizing areas by ex-situ atomic force microscopy. The evolution of surface morphology during a lateral growth of (111) diamond was visualized utilizing a mesa structure as a marker. Lateral growth forms atomically flat surfaces, which show atomically flat terraces over several hundred

Norio Tokuda; Hitoshi Umezawa; Sung-Gi Ri; Masahiko Ogura; Kikuo Yamabe; Hideyo Okushi; Satoshi Yamasaki

2008-01-01

225

High-Risk Infants: Auditory Processing Deficits in Later Childhood.  

ERIC Educational Resources Information Center

To determine whether deficits warranting intervention are present in the later functioning of high-risk infants, 22 premature infants who experienced asphyxia or chronic lung disease (CLD) but who had no gross developmental abnormalities were evaluated. Assessments of auditory perception and receptive language ability were made during later…

Gilbride, Kathleen E.; And Others

226

Development of the Lateral Line System in the Shovelnose Sturgeon  

Microsoft Academic Search

The lateral line systems of aquatic amphibians and all chondrichthyan and osteichthyan fish present a similar array of mechanoreceptors. However, electroreceptors, the second major component of the lateral line system, have clearly undergone more significant evolutionary change. Chondrichthyans and non-neopterygian fish possess primitive ampullary organ electroreceptors, whereas significantly different ‘new’ ampullary organs and tuberous electroreceptors are found in a few

Melissa A. Gibbs; R. Glenn Northcutt

2004-01-01

227

Role of Lateral Body Bending in Crocodylian Track Making  

Microsoft Academic Search

Locomotion in the alligatorids Caiman and Alligator show ontogenetic changes in gait width, manus orientation, and the amount of lateral body movement. In addition, the trackway of an adult Caiman is narrower than predicted for a semierect position of the limbs based on stance. The narrowness of the Caiman trackway is due to lateral movement of the body during locomotion.

Kenneth Carpenter

2009-01-01

228

The Chinese Calendar of The Later Han Period  

E-print Network

The Chinese Calendar of The Later Han Period Undergraduate Research Opportunities Programme would like to learn some basic knowledge in the Chinese calendar, which is an important part explanations to the Chinese calendar of the Later Han period, Shi Fen Li, and introduce some useful

Aslaksen, Helmer

229

Nursery school personality and political orientation two decades later  

Microsoft Academic Search

The present study reports on the personality attributes of nursery school children who two decades later were reliably stratified along a liberal\\/conservative dimension. An unprecedented analytical opportunity existed to evaluate how the political views of these young adults related to assessments of them when in nursery school, prior to their having become political beings. Preschool children who 20 years later

Jack Block; Jeanne H. Block

2006-01-01

230

The Criminal Histories and Later Offending of Child Pornography Offenders  

Microsoft Academic Search

The likelihood that child pornography offenders will later commit a contact sexual offense is unknown. In the present study, we identified a sample of 201 adult male child pornography offenders using police databases and examined their charges or convictions after the index child pornography offense(s). We also examined their criminal records to identify potential predictors of later offenses: 56% of

Michael C. Seto; Angela W. Eke

2005-01-01

231

The Utility of Proximal-Accretion Stratigraphy in Lateral Moraines  

Microsoft Academic Search

Lateral-moraine stratigraphy is a valuable tool that can be used to constrain the timing and magnitude of alpine glacier fluctuations. Numerous lateral moraines, conventionally thought to have been constructed during the Little Ice Age (LIA), have been shown to be composite landforms that contain multiple till layers deposited by successively larger glacier advances. Organic matter and\\/or tephra sandwiched between the

M. A. Samolczyk; G. Osborn

2010-01-01

232

A lateral optical equilibrium in waveguide-resonator optical force  

E-print Network

A lateral optical equilibrium in waveguide-resonator optical force Varat Intaraprasonk,1@stanford.edu Abstract: We consider the lateral optical force between a resonator and a waveguide, and study the possibility of an equilibrium that occurs solely from the optical force in such system. We prove analytically

Fan, Shanhui

233

An unusual metallic foreign body in the lateral tibiofemoral compartment  

Microsoft Academic Search

A child presented with pain and swelling of the knee caused by a fall on the snow. Medical imaging showed an unusual metallic foreign body in the lateral tibiofemoral compartment. Arthroscopy revealed the nature of the foreign body; a metallic piece of stone had penetrated skin and cartilage and was fastened in the cartilage of the lateral femoral condyle where

Marleen Palmers; Carl Dierickx; Patrik Peene; Eric Bijnens

2002-01-01

234

An Immersive Media Model of Amyotrophic Lateral Sclerosis  

E-print Network

1 An Immersive Media Model of Amyotrophic Lateral Sclerosis Federico Visi, Duncan Williams, Eduardo.williams, eduardo.miranda}@plymouth.ac.uk giovanni.dothel@gmail.com 1. INTRODUCTION Amyotrophic lateral sclerosis findings, depicting a deep heterogeneity of the disease, are paving the way for a multi

Miranda, Eduardo Reck

235

The lateral distribution of electrons in extensive air showers  

Microsoft Academic Search

Presents new results of an analysis of the lateral distribution of electrons in extensive air showers. It is shown from experimental data that the lateral distribution of electrons is steeper than the NKG function but not as steep as the function proposed by Lagutin et al. (1979). The author also deduces from the experimental measurements a structure function which yields

D. J. van der Walt

1988-01-01

236

Lateral variations in suspended sediment concentration over dunes  

Technology Transfer Automated Retrieval System (TEKTRAN)

The magnitude of the lateral variations in the concentration of suspended sediment over dunes in an alluvial sand-bed channel are poorly known. Characterizing the lateral distributions of suspended sediment is important for understanding its causes and for accurate measurement of the rate of sedim...

237

LATERAL TURBULENCE INTENSITY AND PLUME MEANDERING DURING STABLE CONDITIONS  

EPA Science Inventory

There is much evidence in the literature for the presence of mesoscale lateral meanders in the stable nighttime boundary layer. These meanders result in relatively high lateral turbulence intensities and diffusion rates when averaged over an hour. Anemometer data from 17 overnigh...

238

Early Speech Perception and Later Language Development: Implications  

E-print Network

Early Speech Perception and Later Language Development: Implications for the "Critical Period and Brain Sciences Department of Speech and Hearing Sciences University of Washington, Seattle In this article, we present a summary of recent research linking speech perception in infancy to later language

239

IQ, Fetal Testosterone and Individual Variability in Children's Functional Lateralization  

ERIC Educational Resources Information Center

Previous event-related potential (ERP) studies have revealed that faces and words show a robust difference in the lateralization of their N170. The present study investigated the development of this differential lateralization in school-age boys. We assessed the potential role of fetal testosterone (FT) level as a factor biasing the prenatal…

Mercure, Evelyne; Ashwin, Emma; Dick, Frederic; Halit, Hanife; Auyeung, Bonnie; Baron-Cohen, Simon; Johnson, Mark H.

2009-01-01

240

PERSPECTIVES: MECHANICAL PROPERTIES Lateral Deformations in Extreme Matter  

E-print Network

PERSPECTIVES: MECHANICAL PROPERTIES Lateral Deformations in Extreme Matter adapted from Lakes, R. S to be impossible (3). Since then, foams with n as small as -0.8 have been produced by changing the shape of the cells (4). These foams expand #12;laterally when stretched. Isotropic negative Poisson's ratio materials

Lakes, Roderic

241

Lateralized tool use in wild New Caledonian crows  

Microsoft Academic Search

Many vertebrate species exhibit sensory and motor asymmetries. Laterality studies of tool use have focused on primates, where hemispheric asymmetries, manifested behaviourally in hand preferences, are thought to be associated with complex motor tasks. Here we report strong individual lateralization for tool use in birds. New Caledonian crows, Corvus moneduloides, hold stick tools with their bills while foraging, often with

Robb Rutledge; GAVIN R. HUNT

2004-01-01

242

Efferent neurons of the lateral line system and their innervation of lateral line branches in a euteleost and an osteoglossomorph  

Microsoft Academic Search

The efferent neurons of the lateral line system of the euteleost Aplocheilus lineatus and the osteoglossomorph Pantodon buchholzi, both surface feeding fish, were examined by neuronal tract tracing. Besides horseradish peroxidase, fluorescent dextrans were used as tracers to allow simultaneus visualization of projections from different lateral line branches. Labeled efferent neurons were found in nuclei situated in the medulla ventral

Thomas Wagner; Erich Schwartz

1996-01-01

243

Deep transverse friction massage for treating lateral elbow or lateral knee tendinitis.  

PubMed

Background Deep transverse friction massage, one of several physical therapy interventions suggested for the management of tendinitis pain, was first demonstrated in the 1930s by Dr James Cyriax, a renowned orthopedic surgeon in England. Its goal is to prevent abnormal fibrous adhesions and abnormal scarring. This is an update of a Cochrane review first published in 2001.Objectives To assess the benefits and harms of deep transverse friction massage for treating lateral elbow or lateral knee tendinitis.Search methods We searched the following electronic databases: the specialized central registry of the Cochrane Field of Physical and Related Therapies,the Cochrane Central Register of Controlled Trials (CENTRAL),MEDLINE, EMBASE, the Cumulative Index to Nursing and Allied Health Literature (CINAHL), Clinicaltrials.gov, and the Physiotherapy Evidence Database (PEDro), up until July 2014. The reference lists of these trials were consulted for additional studies.Selection criteria All randomized controlled trials (RCTs) and controlled clinical trials (CCTs) comparing deep transverse friction massage with control or other active interventions for study participants with two eligible types of tendinitis (ie, extensor carpi radialis tendinitis (lateral elbow tendinitis, tennis elbow or lateral epicondylitis or lateralis epicondylitis humeri) and iliotibial band friction syndrome (lateral knee tendinitis)) were selected. Only studies published in English and French languages were included.Data collection and analysis Two review authors independently assessed the studies on the basis of inclusion and exclusion criteria. Results of individual trials were extracted from the included study using extraction forms prepared by two independent review authors before the review was begun.Data were cross-checked by a third review author. Risk of bias of the included studies was assessed using the "Risk of bias"tool of The Cochrane Collaboration. A pooled analysis was performed using mean difference (MD) for continuous outcomes and risk ratio (RR)for dichotomous outcomes with 95% confidence intervals (CIs).Main results Two RCTs (no new additional studies in this update) with 57 participants met the inclusion criteria. These studies demonstrated high risk of performance and detection bias, and the risk of selection, attrition, and reporting bias was unclear.The first study included 40 participants with lateral elbow tendinitis and compared (1) deep transverse friction massage combined with therapeutic ultrasound and placebo ointment (n = 11) versus therapeutic ultrasound and placebo ointment only (n = 9) and (2)deep transverse friction massage combined with phonophoresis (n = 10) versus phonophoresis only (n = 10). No statistically significant differences were reported within five weeks for mean change in pain on a 0 to 100 visual analog scale (VAS) (MD -6.60, 95%CI -28.60 to 15.40; 7% absolute improvement), grip strength measured in kilograms of force (MD 0.10, 95% CI -0.16 to 0.36) and function ona 0 to 100 VAS (MD -1.80, 95% CI -0.18.64 to 15.04; 2% improvement), pain-free function index measured as the number of painfree items (MD 1.10, 95% CI -1.00 to 3.20) and functional status (RR 3.3, 95% CI 0.4 to 24.3) for deep transverse friction massage,and therapeutic ultrasound and placebo ointment compared with therapeutic ultrasound and placebo ointment only. Likewise for deep transverse friction massage and phonophoresis compared with phonophoresis alone, no statistically significant differences were found for pain (MD -1.2, 95% CI -20.24 to 17.84; 1% improvement), grip strength (MD -0.20, 95% CI -0.46 to 0.06) and function (MD3.70, 95% CI -14.13 to 21.53; 4% improvement). In addition, the GRADE (Grades of Recommendation, Assessment, Development and Evaluation) approach was used to evaluate the quality of evidence for the pain outcome, which received a score of "very low".Pain relief of 30% or greater, quality of life, patient global assessment, adverse events, and withdrawals due to adverse events were not assessed or rep

Loew, Laurianne M; Brosseau, Lucie; Tugwell, Peter; Wells, George A; Welch, Vivian; Shea, Beverley; Poitras, Stephane; De Angelis, Gino; Rahman, Prinon

2014-01-01

244

Active control of lateral balance in human walking.  

PubMed

We measured variability of foot placement during gait to test whether lateral balance must be actively controlled against dynamic instability. The hypothesis was developed using a simple dynamical model that can walk down a slight incline with a periodic gait resembling that of humans. This gait is entirely passive except that it requires active control for a single unstable mode, confined mainly to lateral motion. An especially efficient means of controlling this instability is to adjust lateral foot placement. We hypothesized that similar active feedback control is performed by humans, with fore-aft dynamics stabilized either passively or by very low-level control. The model predicts that uncertainty within the active feedback loop should result in variability in foot placement that is larger laterally than fore-aft. In addition, loss of sensory information such as by closing the eyes should result in larger increases in lateral variability. The control model also predicts a slight coupling between step width and length. We tested 15 young normal human subjects and found that lateral variability was 79% larger than fore-aft variability with eyes open, and a larger increase in lateral variability (53% vs. 21%) with eyes closed, consistent with the model's predictions. We also found that the coupling between lateral and fore-aft foot placements was consistent with a value of 0.13 predicted by the control model. Our results imply that humans may harness passive dynamic properties of the limbs in the sagittal plane, but must provide significant active control in order to stabilize lateral motion. PMID:10940402

Bauby, C E; Kuo, A D

2000-11-01

245

Arthroscopic Lateral Epicondylitis Release Using the “Bayonet” Technique  

PubMed Central

Most patients diagnosed with lateral epicondylitis respond well to conservative management. For patients who do not respond to nonoperative modalities, surgical treatment represents a viable option for long-term symptomatic relief. The arthroscopic surgical technique described in this article has been consistently used by the senior author for the treatment of recalcitrant lateral epicondylitis for more than 5 years (198 patients) without the occurrence of any major complications and appears to be a safe, reliable, and efficacious surgical intervention for the management of lateral epicondylitis. PMID:24749034

Stiefel, Eric C.; Field, Larry D.

2014-01-01

246

30. NORTHERN SEGMENT OF THE LATERAL IN THE NORTHWEST QUARTER ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

30. NORTHERN SEGMENT OF THE LATERAL IN THE NORTHWEST QUARTER OF SECTION 25 STRUCTURE PICTURED IN CO-43-A-28. - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

247

1. HEAD GATE OF THE SAND CREEK LATERAL AT THE ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. HEAD GATE OF THE SAND CREEK LATERAL AT THE HIGH LINE CANAL ON THE SOUTH END OF THE PEORIA STREET BRIDGE. - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

248

11. CONTINUATION OF LATERAL LEAVING THE DIVERSION STRUCTURE WEST OF ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

11. CONTINUATION OF LATERAL LEAVING THE DIVERSION STRUCTURE WEST OF LOWER DERBY LAKE (SECTION 2), SHOWING MEASURING GAUGE. - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

249

12. CONCRETE LINING ON A CURVING SEGMENT OF THE LATERAL ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

12. CONCRETE LINING ON A CURVING SEGMENT OF THE LATERAL NEAR THE NORTHEAST END OF LAKE LADORA (SECTION 2). - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

250

Neuroanatomical correlation of urinary retention in lateral medullary infarction.  

PubMed

We prospectively recruited 10 patients who presented with urinary retention as a neurological deficit that was attributable to lateral medullary infarction. Of these, 9 patients underwent a urodynamic study, which demonstrated detrusor underactivity of the bladder in 7 patients. Urinary retention developed mainly when the lesions involved the lateral tegmentum of the middle or caudal medulla. We concluded that interruption of the descending pathway from the pontine micturition center to the sacral spinal cord in the lateral medulla was responsible for the development of urinary retention. Ann Neurol 2015;77:726-733. PMID:25627980

Cho, Han-Jin; Kang, Tae-Ho; Chang, Jae-Hyeok; Choi, Yu-Ri; Park, Min-Gyu; Choi, Kwang-Dong; Sung, Sang-Min; Park, Kyung-Pil; Jung, Dae-Soo

2015-04-01

251

L’inhalation de corticostéroïdes est-elle sécuritaire durant la grossesse?  

PubMed Central

Résumé Question Une femme atteinte d’asthme léger à modéré, autrement en santé, s’est présentée à ma clinique aujourd’hui après avoir appris qu’elle était enceinte. Elle m’a demandé si elle devait continuer à prendre ses corticostéroïdes en inhalation (CSI) et, dans l’affirmative, s’il pourrait y avoir des risques pour son enfant à naître. Quels seraient vos conseils à ce propos? Réponse Compte tenu des données probantes publiées, les CSI devraient être continués durant toute la grossesse à des doses allant de faibles à modérées et suffisantes pour contrôler les symptômes de l’asthme et prévenir les exacerbations. Il faut toutefois être prudent quand il s’agit de doses de plus de 1 000 µg/j (d’équivalent de béclométasone avec chlorofluorocarbures), quoiqu’il soit actuellement questionnable si de telles doses causeraient des effets indésirables. Il faut renseigner de manière continue les patientes sur l’administration appropriée des CSI et l’observance du traitement, y compris durant le premier trimestre. Un bon contrôle de l’asthme réduira la nécessité de doses plus fortes de CSI et de l’exposition possible à des corticostéroïdes systémiques et diminuera ainsi le risque de résultats périnatals ou de grossesse indésirables.

Smy, Laura; Chan, Alvin C.H.; Bozzo, Pina; Koren, Gideon

2014-01-01

252

Sécurité de la plus récente classe d’antagonistes des opioïdes durant la grossesse  

PubMed Central

Résumé Question J’ai une patiente dont 6 semaines de grossesse viennent d’être confirmées. Depuis 6 mois, elle suit une thérapie pour une dépendance aux opioïdes à l’aide d’une combinaison de buprénorphine et de naloxone. Devrais-je m’inquiéter qu’elle ait été exposée à cette combinaison de médicaments jusqu’à ce stade de sa grossesse? Faudrait-il que je change sa médication pour de la méthadone maintenant qu’elle est enceinte? Réponse Les données limitées sur l’exposition à la buprénorphine durant la grossesse ne révèlent pas d’augmentation du risque de résultats indésirables chez le nouveau-né. Il y a peu de données sur la naloxone durant la grossesse; par ailleurs, on ne s’attendrait pas à ce que l’administration par voie orale soit associée avec un risque accru de résultats de grossesse défavorables. On conseille aux médecins qui traitent des femmes enceintes ou qui deviennent enceintes et dont l’état est stable en prenant une thérapie à la buprénorphine et naloxone de continuer ce traitement mais d’envisager une transition à une monothérapie à la buprénorphine.

Poon, Shirley; Pupco, Anna; Koren, Gideon; Bozzo, Pina

2014-01-01

253

Lateral Casimir force between deeply corrugated dielectric and metallic plates  

E-print Network

We study the lateral Casimir force between corrugated dielectric plates. We use the dielectric contrast perturbation theory [R. Golestanian, {\\it Phys. Rev. Lett.} {\\bf 95}, 230601, (2005)], which allows us to consider arbitrary deformations with large amplitudes. We consider sinusoidal, rectangular, and sawtooth corrugations, for samples made of silicon and gold. We use the plasma and Drude-Lorentz models for the permittivity of gold and silicon, respectively. For these geometries and materials, the lateral Casimir force is {\\it not} a sinusoidal function of the relative lateral displacement of plates when the gap between the plates in comparable with the depth of the corrugations. Our results facilitate the design of miniaturized devices based on lateral Casimir forces.

Arash Azari; MirFaez Miri

2014-09-16

254

Lateral Casimir Force Between Deeply Corrugated Dielectric and Metallic Plates  

NASA Astrophysics Data System (ADS)

We study the lateral Casimir force between corrugated dielectric plates. We use the dielectric contrast perturbation theory [R. Golestanian, Phys. Rev. Lett. 95, 230601, (2005)], which allows us to consider arbitrary deformations with large amplitudes. We consider sinusoidal, rectangular, and sawtooth corrugations, for samples made of silicon and gold. We use the plasma and Drude-Lorentz models for the permittivity of gold and silicon, respectively. For these geometries and materials, the lateral Casimir force is not a sinusoidal function of the relative lateral displacement of plates when the gap between the plates in comparable with the depth of the corrugations. Our results facilitate the design of miniaturized devices based on lateral Casimir forces.

Azari, Arash; Miri, Mirfaez

255

11. Detail of sway braces, struts and top lateral braces' ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

11. Detail of sway braces, struts and top lateral braces' view to north-northwest - Milk River Bridge, Spanning Milk River approximately one mile north of Tampico on Tampico North Road, Tampico, Valley County, MT

256

Being surveyed can change later behavior and related parameter estimates  

E-print Network

Does completing a household survey change the later behavior of those surveyed? In three field studies of health and two of microlending, we randomly assigned subjects to be surveyed about health and/or household finances ...

Zwane, Alix Peterson

257

22. TEMPORARY CENTRIFIGAL PUMP. NOTE CHAPMAN HYDRAULICOPERATED VALVE FOR LATER ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

22. TEMPORARY CENTRIFIGAL PUMP. NOTE CHAPMAN HYDRAULIC-OPERATED VALVE FOR LATER CONNECTION OF ENGINE PUMP END TO DISCHARGE HEADER. - Lakeview Pumping Station, Clarendon & Montrose Avenues, Chicago, Cook County, IL

258

23. TEMPORARY CENTRIFUGAL PUMP. NOTE CHAPMAN HYDRAULICOPERATED VALVE FOR LATER ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

23. TEMPORARY CENTRIFUGAL PUMP. NOTE CHAPMAN HYDRAULIC-OPERATED VALVE FOR LATER CONNECTION OF ENGINE PUMP ENG TO DISCHARGE HEADER. - Lakeview Pumping Station, Clarendon & Montrose Avenues, Chicago, Cook County, IL

259

20. WEB / DECK / LATERAL BRACING DETAIL OF THROUGH ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

20. WEB / DECK / LATERAL BRACING DETAIL OF THROUGH TRUSSES. VIEW TO WEST. - Abraham Lincoln Memorial Bridge, Spanning Missouri River on Highway 30 between Nebraska & Iowa, Blair, Washington County, NE

260

Self-organization and segmentation with laterally connected spiking neurons  

E-print Network

A self-organizing model of spiking neurons with dynamic thresholds and lateral excitatory and inhibitory connections is presented and tested in the image segmentation task. The model integrates two previously separate lines of research in modeling the visual cortex. Laterally connected self-organizing maps have been used to model how afferent structures and lateral connections could self-organize through inputdriven Hebbian adaptation. Spiking neurons with leaky integrator synapses have been used to model image segmentation and binding by synchronization and desynchronization of neuronal activity. Although these approaches differ in how they model the neuron, they have the same overall layout of a laterally connected two-dimensional network. This paper shows how both self-organization and segmentation can be achieved in such a network, thus presenting a unified model of development and functional dynamics in the primary visual cortex. 1

1997-01-01

261

Performance analysis for lateral-line-inspired sensor arrays  

E-print Network

The lateral line is a critical component of the fish sensory system, found to affect numerous aspects of behavior including maneuvering in complex fluid environments, schooling, prey tracking, and environment mapping. This ...

Fernandez, Vicente I

2011-01-01

262

49 CFR 18.51 - Later disallowances and adjustments.  

Code of Federal Regulations, 2010 CFR

...funds due as a result of later refunds, corrections, or other transactions; (c) Records retention as required in § 18.42; (d) Property management requirements in §§ 18.31 and 18.32; and (e) Audit requirements in §...

2010-10-01

263

Directional sensitivity of velocity sense in lateral trunk flexion  

E-print Network

motion were examined during paraspinal muscle vibration. Seventeen healthy subjects performed lateral trunk flexion movements while lying prone with pelvis fixed. A 44.5 Hz vibratory stimulus was applied to the paraspinal muscles at the L3 level...

Soltys, Joseph S.; Wilson, Sara E.

2008-01-04

264

Nerve conduction study of the medial and lateral plantar nerves.  

PubMed

The medial and lateral plantar nerves may be evaluated through the recordings of the compound sensory nerve action potentials (CSNAP), compound mixed nerve action potentials (CMNAP) and compound muscular action potentials (CMAP). As some of these potentials are not easily and always obtainable in normal individuals, our purpose was to verify the consistency of these potentials for the study of these nerves. Fifty-one normal adult volunteers were examined. The CSNAP, CMNAP and CMAP, related to the medial and lateral plantar nerves were evaluated bilaterally. CSNAP were not obtained in 7.8% and in 17.6% from the medial and lateral plantar nerves respectively. CMNAP from the lateral plantar nerve were not obtained in 15.6%. CMNAP from the medial plantar nerves and CMAPs from the abductor hallucis and abductor digiti quinti were obtained for all nerves tested. Our results, therefore, suggest that these last 3 parameters are the ones more reliable for clinical application. PMID:10812535

Antunes, A C; Nobrega, J A; Manzano, G M

2000-01-01

265

Antenna cab interior showing waveguide from external parabolic antenna (later ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Antenna cab interior showing waveguide from external parabolic antenna (later addition), looking north. - Western Union Telegraph Company, Jennerstown Relay, Laurel Summit Road off U.S. 30, Laughlintown, Westmoreland County, PA

266

Economic viability of multiple-lateral horizontal wells  

E-print Network

. It will focus on the application of multiple-lateral horizontal wells to reduce the risks of economic uncertainty associated with poor reservoir characterization in areally anisotropic reservoirs. Using a state-of-the-art productivity index model, the study...

Smith, Christopher Jason

1995-01-01

267

13. DETAIL, LATERAL BRACING FOR INTERIOR OVERHEAD CRANE Delaware, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

13. DETAIL, LATERAL BRACING FOR INTERIOR OVERHEAD CRANE - Delaware, Lackawanna & Western Railroad Freight & Rail Yard, Multiple Unit Light Inspection Shed, New Jersey Transit Hoboken Terminal Rail Yard, Hoboken, Hudson County, NJ

268

8. DETAIL VIEW, LOOKING NORTHEAST, SHOWING OUTRIGGERS FOR LATERAL BRACING ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. DETAIL VIEW, LOOKING NORTHEAST, SHOWING OUTRIGGERS FOR LATERAL BRACING FOR TRUSSES AND BOTTOM CHORD CONNECTIONS. - White Bowstring Arch Truss Bridge, Spanning Yellow Creek at Cemetery Drive (Riverside Drive), Poland, Mahoning County, OH

269

Distant touch hydrodynamic imaging with an artificial lateral line  

PubMed Central

Nearly all underwater vehicles and surface ships today use sonar and vision for imaging and navigation. However, sonar and vision systems face various limitations, e.g., sonar blind zones, dark or murky environments, etc. Evolved over millions of years, fish use the lateral line, a distributed linear array of flow sensing organs, for underwater hydrodynamic imaging and information extraction. We demonstrate here a proof-of-concept artificial lateral line system. It enables a distant touch hydrodynamic imaging capability to critically augment sonar and vision systems. We show that the artificial lateral line can successfully perform dipole source localization and hydrodynamic wake detection. The development of the artificial lateral line is aimed at fundamentally enhancing human ability to detect, navigate, and survive in the underwater environment. PMID:17132735

Yang, Yingchen; Chen, Jack; Engel, Jonathan; Pandya, Saunvit; Chen, Nannan; Tucker, Craig; Coombs, Sheryl; Jones, Douglas L.; Liu, Chang

2006-01-01

270

Detail view, looking west from eastern pier, showing stringers, lateral ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Detail view, looking west from eastern pier, showing stringers, lateral bracing and turnbuckles. - Monongahela Railroad, New Geneva Bridge, Spanning Monongahela River, South of Lock & Dam No. 7, New Geneva, Fayette County, PA

271

14 CFR 25.147 - Directional and lateral control.  

Code of Federal Regulations, 2010 CFR

...inoperative, roll response must allow normal maneuvers. Lateral control must be sufficient...operating, roll response must allow normal maneuvers (such as recovery from upsets produced by gusts and the initiation of evasive maneuvers). There must be enough excess...

2010-01-01

272

Lateral jets improve PDC bit performance in the North Sea  

SciTech Connect

Lateral nozzles built into specially manufactured polycrystalline diamond compact (PDC) bits improve hydraulics at the bit face, thereby increasing penetration rates. The new bit manufacturing process, investment casting, uses a unique body material for PDC drill bits, allowing design freedom for a lateral-jet-hydraulics concept. Lateral jets set into the blades of the bit improve the cutter cleaning efficiency. In addition to cleaning the slot in front of the blade, the jet creates a venturi effect drawing the fluid across the blades serviced by the downward jets. This flow is then ejected at high speed to the junk slots. Increased efficiency of cutter cleaning can directly improve the rate of penetration (ROP). The paper discusses investment casting; drill bits; lateral jet design; initial concept; hydraulics; flow visualization; and results from Beryl field in U.K. Block 9/13 in the northern North Sea.

Lewis, J. (BBL Brit Bit Ltd., Aberdeen (United Kingdom)); Dacre, A. (Mobil North Sea Ltd., Aberdeen (United Kingdom))

1994-06-20

273

Lateral force measurement using a probe fiber as a microlens  

NASA Astrophysics Data System (ADS)

We present a lateral force sensing method for small lateral forces that uses an optical fiber probe as a microlens and measures displacement of the laser spot on a position sensitive detector. We demonstrate that arranging the focus point near the object focal point of the fiber improves the signal intensity and our method combined with synchronous detection can provide a detection limit of the order of 1 pm at a bandwidth of 1 Hz. This indicates that the method enables us to measure lateral force of the order of 1 pN. The method is not restricted by measurement frequency as is the case with tuning fork-based lateral force sensing, and will be a useful method in applications that aim to clarify the intermolecular interaction between the probe and sample by measuring the frequency response, such as nanotribology, nanorheology, interfacial science, and nanobiology.

Fukuzawa, K.; Itoh, S.; Ando, T.; Takahashi, K.; Zhang, H.; Mitsuya, Y.

2004-05-01

274

11. VIEW OF SOUTH BRIDGE PIER, BOTTOM LATERAL BRACING, LOWER ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

11. VIEW OF SOUTH BRIDGE PIER, BOTTOM LATERAL BRACING, LOWER CHORD, STRINGERS, END POST AND BEARING SEAT; FACING SOUTHEAST. - Walker Bridge, Spanning Klamath River and connecting Highway 96 and Walker Road, Klamath River, Siskiyou County, CA

275

Good Sleep in Middle Age May Pay Benefits Later  

MedlinePLUS

... features on this page, please enable JavaScript. Good Sleep in Middle Age May Pay Benefits Later Better ... 27, 2015 Related MedlinePlus Pages Memory Seniors' Health Sleep Disorders TUESDAY, Jan. 27, 2015 (HealthDay News) -- Sleeping ...

276

Performance of a well with lateral and vertical wellbores  

E-print Network

This thesis presents three major topics: analysis of pressure transient behavior of horizontal wells, analysis of pressure transient behavior of slanted wells, and performance analysis of wells with lateral and vertical wellbores. Additional...

Abdat, Toriq

2002-01-01

277

10. EYEBAR PIN CONNECTION JOINING VERTICAL SUSPENSION STRINGER WITH LATERAL ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

10. EYEBAR PIN CONNECTION JOINING VERTICAL SUSPENSION STRINGER WITH LATERAL BRACING MEMBERS - Spruce Street Bridge, East Spruce Street, 500 Block, spanning Power Canal, Sault Ste. Marie, Chippewa County, MI

278

Archives, Records, and Information Management Specialization Fall 2013 and Later  

E-print Network

Archives, Records, and Information Management Specialization ­ Fall 2013 and Later Core Courses _____ LBSC 605 Archival Principles, Practices, and Programs _____ LBSC 631 Achieving Organization Excellence Designing Principled Inquiry MLS Required Course: _____ LBSC 703 Field Study in Archives, Records

Golbeck, Jennifer

279

14. VIEW OF LOG BRIDGE (LATER SUPERSEDED BY THE WIREROPE ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

14. VIEW OF LOG BRIDGE (LATER SUPERSEDED BY THE WIRE-ROPE SUSPENSION BRIDGE), SHOWING OVERHANG WHERE ROCK WAS BLASTED OUT, LOOKING SOUTHWEST - Goat Trail Mining Road, Highway 20, 1.5 miles North of Newhalem, Newhalem, Whatcom County, WA

280

13. VIEW OF LOG BRIDGE (LATER SUPERSEDED BY THE WIREROPE ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

13. VIEW OF LOG BRIDGE (LATER SUPERSEDED BY THE WIRE-ROPE SUSPENSION BRIDGE), SHOWING OVERHANG WHERE ROCK WAS BLASTED OUT, LOOKING NORTHEAST - Goat Trail Mining Road, Highway 20, 1.5 miles North of Newhalem, Newhalem, Whatcom County, WA

281

Equipment boxes (later addition) one level down from antenna cab, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Equipment boxes (later addition) one level down from antenna cab, looking southwest. - Western Union Telegraph Company, Jennerstown Relay, Laurel Summit Road off U.S. 30, Laughlintown, Westmoreland County, PA

282

Detail, external parabolic antenna (later addition). Note how waveguide was ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Detail, external parabolic antenna (later addition). Note how waveguide was cut to remove active portion of antenna. - Western Union Telegraph Company, Jennerstown Relay, Laurel Summit Road off U.S. 30, Laughlintown, Westmoreland County, PA

283

6. Tempe Crosscut Canal, looking west from Division Gates. Lateral ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. Tempe Crosscut Canal, looking west from Division Gates. Lateral at left is for local delivery of irrigation water. Photographer: Mark Durben, February 1989. Source: SRPA - Tempe Canal, South Side Salt River in Tempe, Mesa & Phoenix, Tempe, Maricopa County, AZ

284

Prolonged High Cholesterol in Middle Age Raises Heart Risk Later  

MedlinePLUS

... features on this page, please enable JavaScript. Prolonged High Cholesterol in Middle Age Raises Heart Risk Later: ... ve lived with 11 to 20 years of high cholesterol showed double the risk of heart disease ...

285

Lateral-Pressure Profiles in Cholesterol-DPPC Bilayers  

E-print Network

By means of atomistic molecular dynamics simulations, we study cholesterol-DPPC (dipalmitoyl phosphatidylcholine) bilayers of different composition, from pure DPPC bilayers to a 1:1 mixture of DPPC and cholesterol. The lateral-pressure profiles through the bilayers are computed and separated into contributions from the different components. We find that the pressure inside the bilayer changes qualitatively for cholesterol concentrations of about 20% or higher. The pressure profile then turns from a rather flat shape into an alternating sequence of regions with large positive and negative lateral pressure. The changes in the lateral-pressure profile are so characteristic that specific interaction between cholesterol and molecules such as membrane proteins mediated solely via the lateral-pressure profile might become possible.

Michael Patra

2005-04-05

286

Lateral blasts at Mount St. Helens and hazard zonation  

USGS Publications Warehouse

Lateral blasts at andesitic and dacitic volcanoes can produce a variety of direct hazards, including ballistic projectiles which can be thrown to distances of at least 10 km and pyroclastic density flows which can travel at high speed to distances of more than 30 km. Indirect effect that may accompany such explosions include wind-borne ash, pyroclastic flows formed by the remobilization of rock debris thrown onto sloping ground, and lahars. Two lateral blasts occurred at a lava dome on the north flank of Mount St. Helens about 1200 years ago; the more energetic of these threw rock debris northeastward across a sector of about 30?? to a distance of at least 10 km. The ballistic debris fell onto an area estimated to be 50 km2, and wind-transported ash and lapilli derived from the lateral-blast cloud fell on an additional lobate area of at least 200 km2. In contrast, the vastly larger lateral blast of May 18, 1980, created a devastating pyroclastic density flow that covered a sector of as much as 180??, reached a maximum distance of 28 km, and within a few minutes directly affected an area of about 550 km2. The May 18 lateral blast resulted from the sudden, landslide-induced depressurization of a dacite cryptodome and the hydrothermal system that surrounded it within the volcano. We propose that lateral-blast hazard assessments for lava domes include an adjoining hazard zone with a radius of at least 10 km. Although a lateral blast can occur on any side of a dome, the sector directly affected by any one blast probably will be less than 180??. Nevertheless, a circular hazard zone centered on the dome is suggested because of the difficulty of predicting the direction of a lateral blast. For the purpose of long-term land-use planning, a hazard assessment for lateral blasts caused by explosions of magma bodies or pressurized hydrothermal systems within a symmetrical volcano could designate a circular potential hazard area with a radius of 35 km centered on the volcano. For short-term hazard assessments, if seismicity and deformation indicate that magma is moving toward the flank of a volcano, it should be recognized that a landslide could lead to the sudden unloading of a magmatic or hydrothermal system and thereby cause a catastrophic lateral blast. A hazard assessment should assume that a lateral blast could directly affect an area at least 180?? wide to a distance of 35 km from the site of the explosion, irrespective of topography. ?? 1986 Springer-Verlag.

Crandell, D.R.; Hoblitt, R.P.

1986-01-01

287

Lateral crural tensioning for refinement of the wide and underprojected nasal tip: rethinking the lateral crural steal.  

PubMed

Refinement of the wide, ptotic, under protected tip is one of the most difficult challenges in cosmetic nasal surgery yet also among the most common. Although excisional techniques can produce reductions in lobular width, long-term contour alterations are unpredictable and subject to stigmatic tip deformity. Preservation of natural tip support is a fundamental requirement of a successful rhinoplasty. The traditional lateral crural steal is a useful technique for tip refinement, but, when combined with a sturdy septal extension graft, the modified lateral crural steal (lateral crural tensioning) becomes a more potent and versatile rhinoplasty technique that can improve tip contour without jeopardizing function or structural stability. PMID:25430927

Davis, Richard E

2015-02-01

288

Large Lateral Photovoltaic Effect in Metal-(Oxide-) Semiconductor Structures  

PubMed Central

The lateral photovoltaic effect (LPE) can be used in position-sensitive detectors to detect very small displacements due to its output of lateral photovoltage changing linearly with light spot position. In this review, we will summarize some of our recent works regarding LPE in metal-semiconductor and metal-oxide-semiconductor structures, and give a theoretical model of LPE in these two structures. PMID:22163463

Yu, Chongqi; Wang, Hui

2010-01-01

289

Lateral epicondylitis in tennis: update on aetiology, biomechanics and treatment  

PubMed Central

Lateral epicondylitis (tennis elbow) is the most frequent type of myotendinosis and can be responsible for substantial pain and loss of function of the affected limb. Tennis biomechanics, player characteristics and equipment are important in preventing the condition. This article presents an overview of the current knowledge on lateral epicondylitis, and focuses on treatment strategies. Conservative and surgical treatment options are discussed, and recent techniques are outlined. PMID:17616547

De Smedt, Thomas; de Jong, Andy; Van Leemput, Wim; Lieven, Dossche; Van Glabbeek, Francis

2007-01-01

290

Airplane performance sensitivities to lateral and vertical profiles  

Microsoft Academic Search

Airplane performance sensitivity to the choice of lateral and vertical profiles is studied based on data recorded on in-service flights of a 727-200 airplane equipped with JT9D-7 engines. Lateral profile performance sensitivity is based on analysis of flight technical or guidance error and on varying degrees of direct flight clearance. Vertical analysis is based on an aerodynamic simulation of the

J. C. Wauer; J. M. H. Bruckner

2009-01-01

291

Lateral prefrontal cortex and self-control in intertemporal choice.  

PubMed

Disruption of function of left, but not right, lateral prefrontal cortex (LPFC) with low-frequency repetitive transcranial magnetic stimulation (rTMS) increased choices of immediate rewards over larger delayed rewards. rTMS did not change choices involving only delayed rewards or valuation judgments of immediate and delayed rewards, providing causal evidence for a neural lateral-prefrontal cortex-based self-control mechanism in intertemporal choice. PMID:20348919

Figner, Bernd; Knoch, Daria; Johnson, Eric J; Krosch, Amy R; Lisanby, Sarah H; Fehr, Ernst; Weber, Elke U

2010-05-01

292

Discoid lateral meniscus: diagnosis and results of arthroscopic treatment  

Microsoft Academic Search

We evaluated the results of arthroscopic meniscectomy in patients with discoid lateral menisci of the knee. Discoid lateral menisci were detected in 308 patients, of whom 197 (124 males, 73 females; mean age 34.5 years, range 6-67) were clinically, radiologically, and arthroscopically found to be symptomatic and underwent partial meniscectomy. The average period between injury and operation was 13.2 months

Mehmet Asik; Cengiz Sen; Omer F. Taser; Aziz K. Alturfan; Yunus V. Sozen

2003-01-01

293

Endodontic treatment of maxillary lateral incisors with anatomical variations  

PubMed Central

Maxillary lateral incisors usually exhibit a single root with a single canal. However, maxillary lateral incisor teeth with unusual morphology of root canal system are frequently reported. These cases of variable root canal anatomy can be treated well by nonsurgical endodontic methods. A detailed description of root canal morphology is fundamental for successful endodontic treatment. Treatment using an operating microscope, radiographs from different angles, and cone-beam computerized tomography (CBCT) can produce more predictable endodontic outcomes. PMID:24303362

Lee, Moon-Hwan; Ha, Jung-Hong; Jin, Myoung-Uk; Kim, Young-Kyung

2013-01-01

294

Delta-Notch Lateral Inhibition within the Organ of Corti  

NASA Astrophysics Data System (ADS)

Lateral inhibition is described as an emergent property of the Delta-Notch signalling network. Two separate model representations of lateral inhibition are proposed for different purposes. One provides information about bioenergetics while the other has the capability to produce a physical representation. It is proposed that both can be used in further studies of the sensory pathways in the human connectome model of brain function.

Summers, R.; Abdulla, T.; Luff, R.

2013-09-01

295

Infant Feeding Practices in Barbados Predict Later Growth  

Microsoft Academic Search

ABSTRACT This longitudinal study was,designed,to examine,reciprocal relationships between,feeding practices and infant growth,over the first 6 mo,of life. The following three hypotheses,were,tested: 1) early feeding practices predict later infant growth; 2) early infant growth,predicts,later feeding practices; and,3) these relationships,occur after controlling for related background variables. The sample included 226 healthy, well-nourished infants born at the Queen Elizabeth Hospital, Bridgetown, Barbados. Assessments

Janina R. Galler; Frank C. Ramsey; Robert H. Harrison; Rechele Brooks; Sally Weiskopf-bock

296

Specificity of serotoninergic inhibition in Limulus lateral eye  

Microsoft Academic Search

A B STR ACT The receptor specificity for synaptically mediated lateral inhibi- tion in Limulus lateral eye retina was studied by structure-activity correlations of the action of the putative indoleaminergic neurotransmitter, serotonin (5-HT), and its isomers and structural analogs, tryptamine (TRYP), 6-hyroxytryptamine (6HT), 5,6-dihydroxytryptamine (5,6-DHT), 5-hyroxydimethyhryptamine (5- HDMT), and 5-hydroxytryptophan (5-HTP). The 5-HT blockers, lysergic acid diethylamide (LSD), bromo-LSD (BOL),

ALAN R. ADOLPH; LEONARD KASS

1979-01-01

297

Lateral imbalance detection on a UAV based on multiple models  

Microsoft Academic Search

This paper addresses a multiple-model based lateral imbalance detection methodology for an uninhabited air vehicle (UAV). Two critical imbalance failures are considered that are the failure-induced left aileron stuck and the centre-of-gravity shift along the y-axis. A bank of LTI Kalman filters are designed to detect the above lateral failures and a flight control law based on the model predictive

Sajjad Fekri; Da-Wei Gu; Ian Postlethwaite

2009-01-01

298

Spin injection, diffusion and detection in lateral spin valves  

NASA Astrophysics Data System (ADS)

Metallic heterostructures involving ferromagnetic metals (FM) and non-magnetic metals (NM) offer very rich spintronic phenomena, such as giant magnetoresistance and spin-transfer torque. Recently, new interests have been found in heterostructures that feature lateral variation of materials. The motivation originates from the possibility of lateral integration of future spintronic devices and the advantage of extra degrees of freedom in controlling spin accumulation offered by lateral structures. In this work, we demonstrate non- local spin injection and detection in lateral spin valves. A lateral spin valve consists of a NM nanowire connected with two FM electrodes, one as the spin injector and the other as the spin detector. The measurement configurations are arranged in such a way that the current injection circuit and voltage detection circuit are separated, and so are the charge current and the spin current. A pure spin current without charge flow can be obtained in lateral spin valves, and the detected spin signal exhibits very large percentage change. The spin accumulation in lateral spin valves strongly depends on the spin diffusion length of the NM and the injection polarization of FM/NM interface, both of which can be determined by measuring a series of spin valves with different injector detector separations. We have determined the spin diffusion lengths and injection polarizations for Py/Au/Py and Co/Cu/Co lateral spin valves, fabricated by different techniques. The differences of these quantities in two systems will be discussed. This work is done in collaboration with Axel Hoffmann, Sam Jiang, John Pearson, and Sam Bader, and supported by U.S. DOE Office of Basic Energy Science-Materials Science under contract No. W-31- 109-ENG-38.

Ji, Yi

2006-03-01

299

Atividade antioxidante e captora de radicais livres dos extratos de Achyrocline alata (Kunth.) DC. em comparação com extratos de Achyrocline satureioides (Lam.) DC  

Microsoft Academic Search

RESUMO: Achyrocline alata (Kunth.) DC. e Achyrocline satureioides (Lam.) DC., espécies pertencentes à família Asteraceae, são utilizadas na medicina popular de Campo Grande, Mato Grosso do Sul, como plantas sucedâneas. O presente trabalho teve com objetivo comparar os extratos obtidos dessas espécies através de ensaios químicos simples destinados a testar as atividades antioxidante e captora de radicais livres, utilizando como

Rafaela F. Grassi-Zampieron; Maria C. Vieira; João M. de Siqueira

2009-01-01

300

Lateral Thinking About Leptin: A Review of Leptin Action via the Lateral Hypothalamus  

PubMed Central

The lateral hypothalamic area (LHA) was initially described as a “feeding center” but we are now beginning to understand that the LHA contributes to other aspects of physiology as well. Indeed, the best-characterized neuronal populations of the LHA (which contain melanin-concentrating hormone (MCH) or the hypocretins/orexins (OX) are not strictly orexigenic, but also have roles in regulation of the autonomic and sympathetic nervous systems as well as in modulating motivated behavior. Leptin is an anorectic hormone that regulates energy homeostasis and the mesolimbic DA system (which transduces the wanting of food, drugs of abuse and sex) in part, via actions at the LHA. At least three populations of LHA neurons are regulated by leptin: those containing MCH, OX or the long form of the leptin receptor, LepRb. The emerging picture of leptin interaction with these LHA populations suggests that the LHA is not merely regulating feeding, but is a crucial integrator of energy balance and motivated behavior. PMID:21550356

Leinninger, Gina M.

2011-01-01

301

Lockhart Clarke's contribution to the description of amyotrophic lateral sclerosis.  

PubMed

The definition of the clinicopathological entity of amyotrophic lateral sclerosis evolved over half a century. Although the definitive term amyotrophic lateral sclerosis that acknowledged both upper and lower motor neuron involvement was attributed to Jean-Martin Charcot in 1874, his initial case was published nearly a decade earlier; and it is accepted that, from at least the 1830s, several others (including Charles Bell, François-Amilcar Aran and Jean Cruveilhier) had already recognized a progressive lower motor neuron-only syndrome within a broader, clinically-defined group of disorders, termed progressive muscular atrophy. Although William Gowers first grouped the three phenotypes of amyotrophic lateral sclerosis, progressive muscular atrophy and progressive bulbar palsy together as part of the same syndrome, the term motor neuron disease, as an over-arching label, was not suggested until nearly a century later by W. Russell Brain. Augustus Jacob Lockhart Clarke (1817-80) is best known for his descriptions of spinal cord anatomy. However, in two detailed case reports from the 1860s, he carried out rigorous post-mortem neuropathological studies of what appear to be classical cases of amyotrophic lateral sclerosis. Furthermore, he recognized the additional involvement of the corticospinal tracts that distinguished this from progressive muscular atrophy. Several aspects of the exquisite clinical histories documented as part of both studies, one by Charles Bland Radcliffe, resonate with contemporary debates concerning the evolution of disease in amyotrophic lateral sclerosis. These 'past masters' still have much to teach us. PMID:20576696

Turner, Martin R; Swash, Michael; Ebers, George C

2010-11-01

302

Functional Anatomy, Pathomechanics, and Pathophysiology of Lateral Ankle Instability  

PubMed Central

Objective: To describe the functional anatomy of the ankle complex as it relates to lateral ankle instability and to describe the pathomechanics and pathophysiology of acute lateral ankle sprains and chronic ankle instability. Data Sources: I searched MEDLINE (1985–2001) and CINAHL (1982–2001) using the key words ankle sprain and ankle instability. Data Synthesis: Lateral ankle sprains are among the most common injuries incurred during sports participation. The ankle functions as a complex with contributions from the talocrural, subtalar, and inferior tibiofibular joints. Each of these joints must be considered in the pathomechanics and pathophysiology of lateral ankle sprains and chronic ankle instability. Lateral ankle sprains typically occur when the rearfoot undergoes excessive supination on an externally rotated lower leg. Recurrent ankle sprain is extremely common; in fact, the most common predisposition to suffering a sprain is the history of having suffered a previous ankle sprain. Chronic ankle instability may be due to mechanical instability, functional instability, or most likely, a combination of these 2 phenomena. Mechanical instability may be due to specific insufficiencies such as pathologic laxity, arthrokinematic changes, synovial irritation, or degenerative changes. Functional instability is caused by insufficiencies in proprioception and neuromuscular control. Conclusions/Recommendations: Lateral ankle sprains are often inadequately treated, resulting in frequent recurrence of ankle sprains. Appreciation of the complex anatomy and mechanics of the ankle joint and the pathomechanics and pathophysiology related to acute and chronic ankle instability is integral to the process of effectively evaluating and treating ankle injuries. PMID:12937557

Hertel, Jay

2002-01-01

303

Initiation and elongation of lateral roots in Lactuca sativa  

NASA Technical Reports Server (NTRS)

Lactuca sativa cv. Baijianye seedlings do not normally produce lateral roots, but removal of the root tip or application of auxin, especially indole-butyric acid, triggered the formation of lateral roots. Primordia initiated within 9 h and were fully developed after 24 h by activating the pericycle cells opposite the xylem pole. The pericycle cells divided asymmetrically into short and long cells. The short cells divided further to form primordia. The effect of root tip removal and auxin application was reversed by 6-benzylaminopurine at concentrations >10(-8) M. The cytokinin oxidase inhibitor N1-(2chloro4pyridyl)-N2-phenylurea also suppressed auxin-induced lateral rooting. The elongation of primary roots was promoted by L-alpha-(2-aminoethoxyvinyl) glycine and silver ions, but only the latter enhanced elongation of lateral roots. The data indicate that the induction of lateral roots is controlled by basipetally moving cytokinin and acropetally moving auxin. Lateral roots appear to not produce ethylene.

Zhang, N.; Hasenstein, K. H.

1999-01-01

304

Lateral line diversity among ecologically divergent threespine stickleback populations  

PubMed Central

The lateral line is a mechanoreceptive sensory system that allows fish to sense objects and motion in their local environment. Variation in lateral line morphology may allow fish in different habitats to differentially sense and respond to salient cues. Threespine sticklebacks (Gasterosteus aculeatus) occupy a diverse range of aquatic habitats; we therefore hypothesized that populations within the G. aculeatus species complex might show variation in the morphology of the lateral line sensory system. We sampled 16 threespine stickleback populations from marine, stream and lake (including benthic and limnetic) habitats and examined the distribution, type and number of neuromasts on different regions of the body. We found that the threespine stickleback has a reduced lateral line canal system, completely lacking canal neuromasts. Although the arrangement of lines of superficial neuromasts on the body was largely the same in all populations, the number of neuromasts within these lines varied across individuals, populations and habitats. In pairwise comparisons between threespine sticklebacks adapted to divergent habitats, we found significant differences in neuromast number. Stream residents had more neuromasts than marine sticklebacks living downstream in the same watershed. In two independent lakes, benthic sticklebacks had more trunk neuromasts than sympatric limnetic sticklebacks, providing evidence for parallel evolution of the lateral line system. Our data provide the first demonstration that the lateral line sensory system can vary significantly between individuals and among populations within a single species, and suggest that this sensory system may experience different selection regimes in alternative habitats. PMID:20008367

Wark, A. R.; Peichel, C. L.

2010-01-01

305

Lateral line depigmentation (LLD) in channel catfish, Ictalurus punctatus (Rafinesque).  

PubMed

Head and lateral line erosion (HLLE) is a chronic dermatopathy affecting a number of fish that presents as depigmented skin along the lateral line system of the trunk and head. We present microbiological, immunological and histopathological features of this lesion in channel catfish, Ictalurus punctatus (Rafinesque), that developed after exposure to a chronic nutritional stress. Depigmention was limited to skin that was adjacent to the lateral line. The epidermis of affected fish was thin and reduced to a one-cell-thick layer over the lateral line. Melanocytes were depleted at the dermo-epidermal junction and formed aggregates in the epidermis. Innate immunity was weaker in affected fish than that previously measured in well-fed channel catfish. Because the pathology and apparent aetiology of HLLE described in various fish species are highly variable, HLLE appears to be a clinical sign, rather than a disease or syndrome. Thus, we propose that this clinical sign be referred to as lateral line depigmentation (LLD), because this description more accurately encompasses all cases of this presentation reported in fish. As nutritional requirements of channel catfish and lateral line neuroanatomy are well-known, the ability to reproducibly induce LLD in this species could provide a useful model for understanding its pathogenesis. PMID:19531093

Corrales, J; Ullal, A; Noga, E J

2009-08-01

306

Extra-articular Mimickers of Lateral Meniscal Tears  

PubMed Central

Context: Lateral meniscus tears are a common entity seen in sports medicine. Although lateral-side knee pain is often the result of a meniscus injury, several extra-articular pathologies share signs and symptoms with a meniscus tear. It is critical for the clinician to be able to identify and understand extra-articular pathologies that can present similar to a lateral meniscus tear. Evidence Acquisition: Data were collected through a thorough review of the literature conducted through a MEDLINE search for all relevant articles between 1980 and February 2010. Study Type: Clinical review. Results: Common extra-articular pathologies that can mimic lateral meniscal tears include iliotibial band syndrome, proximal tibiofibular joint instability, snapping biceps femoris or popliteus tendons, and peroneal nerve compression syndrome or neuritis. The patient history, physical examination features, and radiographic findings can be used to separate these entities from the more common intra-articular knee pathologies. Conclusions: In treating patients who present with lateral-sided knee pain, clinicians should be able to recognize and treat extra-articular pathologies that can present in a similar fashion as lateral meniscus tears. PMID:23015995

Barker, Joseph U.; Strauss, Eric J.; Lodha, Sameer; Bach, Bernard R.

2011-01-01

307

Licensing stop place before laterals : a study of acoustic cues relevant to the perception of stop-lateral sequences  

E-print Network

In phonological analyses of both adult and child language, a *dl constraint has frequently been used as a shorthand to indicate that coronal stops are dispreferred before laterals (Dinnsen et al. 2001). This dispreference ...

Michaels, Jennifer M. (Jennifer Marie)

2011-01-01

308

Fold patterns, lateral ramps and seismicity in central Pennsylvania  

USGS Publications Warehouse

The Susquehanna lateral ramp crosses the entire length of Pennsylvania in a NNE direction and extends into southern New York State. Its presence was first suspected because of a dramatic change in fold wavelength across the Susquehanna River, seen on both side-looking airborne radar (SLAR *) data and the geologic map of Pennsylvania. Seismic reflection profiles confirm the presence of a ramp and show the detailed nature of structures associated with it. These structures include antiformal stacks, juxtaposed anticlines and synclines, and folds beheaded by thrust faults. The change in the fold pattern, which led to recognizing the lateral ramp, occurs above a rapid dropoff in depth to the basement suggesting that the ramp and the basement configuration may somehow be related. In plan view, eleven earthquakes are spatially related to the Susquehanna lateral ramp, although they are in the basement rocks rather than in the cover rocks which contain the lateral ramp itself. The earthquakes are, therefore, not likely directly associated with the ramp, though they may be affiliated with strike-slip faulting in the basement which, itself, appears to be partly responsible for the formation of the ramp. The initial age of the faulting along, and in the vicinity of, the Susquehanna lateral ramp is presumably Early to Middle Paleozoic. However, the presence of a surficially-exposed Mesozoic dike along the ramp and modern seismicity suggest that the Susquehanna lateral ramp may be a zone of protracted, and perhaps repeated, tectonism which is currently being reactivated. A preliminary evaluation of the distribution of modern earthquakes in the Valley and Ridge, Blue Ridge and Appalachian Plateau shows that nearly half of the earthquakes are located under lateral ramps. If this observation is true, the presence of ramps may be a useful geological indicator of areas susceptible to seismicity. ?? 1991.

Pohn, H.A.; Coleman, J.L., Jr.

1991-01-01

309

Form matters: morphological aspects of lateral root development  

PubMed Central

Background The crucial role of roots in plant nutrition, and consequently in plant productivity, is a strong motivation to study the growth and functioning of various aspects of the root system. Numerous studies on lateral roots, as a major determinant of the root system architecture, mostly focus on the physiological and molecular bases of developmental processes. Unfortunately, little attention is paid either to the morphological changes accompanying the formation of a lateral root or to morphological defects occurring in lateral root primordia. The latter are observed in some mutants and occasionally in wild-type plants, but may also result from application of external factors. Scope and Conclusions In this review various morphological aspects of lateral branching in roots are analysed. Morphological events occurring during the formation of a typical lateral root are described. This process involves dramatic changes in the geometry of the developing organ that at early stages are associated with oblique cell divisions, leading to breaking of the symmetry of the cell pattern. Several types of defects in the morphology of primordia are indicated and described. Computer simulations show that some of these defects may result from an unstable field of growth rates. Significant changes in both primary and lateral root morphology may also be a consequence of various mutations, some of which are auxin-related. Examples reported in the literature are considered. Finally, lateral root formation is discussed in terms of mechanics. In this approach the primordium is considered as a physical object undergoing deformation and is characterized by specific mechanical properties. PMID:24190952

Szymanowska-Pu?ka, Joanna

2013-01-01

310

Lateral canthoplasty with acellular cadaveric dermal matrix graft (AlloDerm) reinforcement.  

PubMed

Lateral canthal dystopia can lead to lower eyelid malposition, abnormal lateral eyelid fissure appearance, and lagophthalmos. In most cases, the lateral canthus can be repaired with a standard lateral canthopexy or canthoplasty. In a fraction of cases, especially when recurrent, the surgical repair may require additional lateral canthal reinforcement. PMID:21629140

Dailey, Roger A; Chavez, Mauricio R

2012-01-01

311

The Utility of Proximal-Accretion Stratigraphy in Lateral Moraines  

NASA Astrophysics Data System (ADS)

Lateral-moraine stratigraphy is a valuable tool that can be used to constrain the timing and magnitude of alpine glacier fluctuations. Numerous lateral moraines, conventionally thought to have been constructed during the Little Ice Age (LIA), have been shown to be composite landforms that contain multiple till layers deposited by successively larger glacier advances. Organic matter and/or tephra sandwiched between the till layers constrain times of advance and retreat; wood fragments within till may provide the age of the till. Observation of contemporary lateral moraines has lead to the recognition of two means of lateral moraine construction: (1) accretion of tills onto the distal flank of the pre-existing lateral moraine, and (2) accretion or plastering of tills onto the proximal flank of the pre-existing moraine. In composite lateral moraines, distal and proximal accretion result in paleosurfaces that trend parallel to the current distal and proximal slope, respectively. Published work using lateral-moraine stratigraphy, for example at Bugaboo and Stutfield glaciers in the Canadian Rockies, has used evidence only from distal-accretion moraines. However, proximal-accretion moraines that provide chronological information have been found at Nisqually Glacier on Mount Rainier in Washington State, USA, and Columbia Glacier, an outlet of the Columbia Icefield in the Canadian Rockies. A gully cut into the left-lateral moraine at Nisqually Glacier exposes a sandy seam, with associated wood fragments, that runs parallel to the proximal moraine flank for ~20 m. Wood collected from different elevations along the seam have radiocarbon ages of 1715±15, 1700±15, and 1670±50 14C yr BP, indicating that the seam is similar in age along its extent and likely marks a paleosurface separating older till below and till of the First Millennium advance above. At Columbia Glacier, some till exposures in the prominent right-lateral moraine show a fissility dipping variably 40 to 50° toward the valley axis; this orientation is semi-parallel to the proximal flank of the moraine, which however is steeper due to ongoing erosion. Five wood fragments encased in the till over a broad area of the flank, and exposed by gullying, have ages ranging from 1920±70 to 2340±70 14C yr BP. This suggests that (1) most of what appears to be a LIA moraine was deposited in earlier Neoglacial time, and (2) that the glacier was nearly as extensive ca. 2400-1900 ka as it was during the LIA.

Samolczyk, M. A.; Osborn, G.

2010-12-01

312

Comparison of laparoscopic versus open left lateral segmentectomy  

PubMed Central

Background: Although there are data in the literature about the safety and efficacy of laparoscopic liver resections, there are not many studies comparing laparoscopic versus open approaches in a case-matched design. This study was designed to compare perioperative outcomes of the left lateral segmentectomy via laparoscopic and open approach. Methods: From January 2009 to January 2013, we performed left lateral segmentectomies in 60 patients, those excluded from analysis included previous liver resections, polycystic liver disease and liver cirrhosis. Laparoscopic left lateral segmentectomy was performed in 30 patients and open left lateral segmentectomy was performed in 20 patients. All clinical data were analyzed retrospectively. Results: The mean duration of operation was 120 ± 30.4 min in the LLS and 150 ± 36.8 min in the OLS group, no statistically significant difference was found between the two groups. The median blood loss in LLS group was less than that in OLS group (200 ± 22.1 ml versus 328 ± 36.8 ml, P < 0.05). Mean post-operative hospital stay was significantly lower in LLS compared with OLS (5 ± 0.9 vs. 8 ± 1.0; P < 0.05). The postoperative morbidity rate was also significantly different between the groups, a tendency towards more severe complications in the OLS group compared with LLS group. Conclusion: Laparoscopic left lateral segmentectomy can decrease complications, shorten hospitalization time, is a minimally invasive, safe and effective way.

Zhang, Yue; Chen, Xue-Min; Sun, Dong-Lin

2015-01-01

313

Lateral position detection and control for friction stir systems  

DOEpatents

A friction stir system for processing at least a first workpiece includes a spindle actuator coupled to a rotary tool comprising a rotating member for contacting and processing the first workpiece. A detection system is provided for obtaining information related to a lateral alignment of the rotating member. The detection system comprises at least one sensor for measuring a force experienced by the rotary tool or a parameter related to the force experienced by the rotary tool during processing, wherein the sensor provides sensor signals. A signal processing system is coupled to receive and analyze the sensor signals and determine a lateral alignment of the rotating member relative to a selected lateral position, a selected path, or a direction to decrease a lateral distance relative to the selected lateral position or selected path. In one embodiment, the friction stir system can be embodied as a closed loop tracking system, such as a robot-based tracked friction stir welding (FSW) or friction stir processing (FSP) system.

Fleming, Paul (Boulder, CO); Lammlein, David (Houston, TX); Cook, George E. (Brentwood, TN); Wilkes, Don Mitchell (Nashville, TN); Strauss, Alvin M. (Nashville, TN); Delapp, David (Ashland City, TN); Hartman, Daniel A. (Santa Fe, NM)

2010-12-14

314

Post-seismic relaxation theory on laterally heterogeneous viscoelastic model  

USGS Publications Warehouse

Investigation was carried out into the problem of relaxation of a laterally heterogeneous viscoelastic Earth following an impulsive moment release event. The formal solution utilizes a semi-analytic solution for post-seismic deformation on a laterally homogeneous Earth constructed from viscoelastic normal modes, followed by application of mode coupling theory to derive the response on the aspherical Earth. The solution is constructed in the Laplace transform domain using the correspondence principle and is valid for any linear constitutive relationship between stress and strain. The specific implementation described in this paper is a semi-analytic discretization method which assumes isotropic elastic structure and a Maxwell constitutive relation. It accounts for viscoelastic-gravitational coupling under lateral variations in elastic parameters and viscosity. For a given viscoelastic structure and minimum wavelength scale, the computational effort involved with the numerical algorithm is proportional to the volume of the laterally heterogeneous region. Examples are presented of the calculation of post-seismic relaxation with a shallow, laterally heterogeneous volume following synthetic impulsive seismic events, and they illustrate the potentially large effect of regional 3-D heterogeneities on regional deformation patterns.

Pollitz, F.F.

2003-01-01

315

Pericycle cell proliferation and lateral root initiation in Arabidopsis.  

PubMed

In contrast with other cells generated by the root apical meristem in Arabidopsis, pericycle cells adjacent to the protoxylem poles of the vascular cylinder continue to cycle without interruption during passage through the elongation and differentiation zones. However, only some of the dividing pericycle cells are committed to the asymmetric, formative divisions that give rise to lateral root primordia (LRPs). This was demonstrated by direct observation and mapping of mitotic figures, cell-length measurements, and the histochemical analysis of a cyclin-GUS fusion protein in pericycle cells. The estimated duration of a pericycle cell cycle in the root apical meristem was similar to the interval between cell displacement from the meristem and the initiation of LRP formation. Developmentally controlled LRP initiation occurs early, 3 to 8 mm from the root tip. Thus the first growth control point in lateral root formation is defined by the initiation of primordia in stochastic patterns by cells passing through the elongation and young differentiation zones, up to where lateral roots begin to emerge from the primary root. Therefore, the first growth control point is not restricted to a narrow developmental window. We propose that late LRP initiation is developmentally unrelated to the root apical meristem and is operated by a second growth control point that can be activated by environmental cues. The observation that pericycle cells divide and lateral root primordia form without intervening mitotic quiescence suggests that lateral organ formation in roots and shoots might not be as fundamentally different as previously thought. PMID:11115882

Dubrovsky, J G; Doerner, P W; Colón-Carmona, A; Rost, T L

2000-12-01

316

Recent regional lateral carbon fluxes in the conterminous United States  

NASA Astrophysics Data System (ADS)

Rivers and streams form linkages among multiple carbon (C) reservoirs, including terrestrial landscapes, the ocean, and the atmosphere. Given that recent global studies have estimated that these fluvial networks transport a significant portion of terrestrial C stocks, lateral export of C via rivers and streams may have important implications for accurate assessment of regional C budgets. Our objective is to estimate recent (2000 to 2010) regional dissolved inorganic carbon (DIC), dissolved organic carbon (DOC), and total organic carbon (TOC) lateral fluxes for the conterminous US; the regions defined in this study were based on the US Geological Survey hydrologic accounting units. Lateral fluxes can be estimated using concentration and streamflow data available from the USGS. We use a multiple regression approach that estimates daily flux as a function of streamflow, seasonality, and time, where daily fluxes can be summed and expressed on an annual basis. We find significant differences in regional DIC, DOC, and TOC fluxes, and DIC represents a significant portion of the total lateral C flux. The results demonstrate the need to account for lateral fluxes in regional C budgets, as they may represent five percent or more of total ecosystem production.

Stackpoole, S. M.; Stets, E. G.; Butman, D. E.; Striegl, R. G.

2011-12-01

317

Stabilization control of a hovering model insect: lateral motion  

NASA Astrophysics Data System (ADS)

Our previous study shows that the lateral disturbance motion of a model drone fly does not have inherent stability (passive stability), because of the existence of an unstable divergence mode. But drone flies are observed to fly stably. Constantly active control must be applied to stabilize the flight. In this study, we investigate the lateral stabilization control of the model drone fly. The method of computational fluid dynamics is used to compute the lateral control derivatives and the techniques of eigenvalue and eigenvector analysis and modal decomposition are used for solving the equations of motion. Controllability analysis shows that although inherently unstable, the lateral disturbance motion is controllable. By feeding back the state variables (i.e. lateral translation velocity, yaw rate, roll rate and roll angle, which can be measured by the sensory system of the insect) to produce anti-symmetrical changes in stroke amplitude and/or in angle of attack between the left and right wings, the motion can be stabilized, explaining why the drone flies can fly stably even if the flight is passively unstable.

Zhang, Yan-Lai; Sun, Mao

2011-10-01

318

Embryonic exposure to predator odour modulates visual lateralization in cuttlefish  

PubMed Central

Predation pressure acts on the behaviour and morphology of prey species. In fish, the degree of lateralization varies between high- and low-predation populations. While lateralization appears to be widespread in invertebrates, we do not know whether heredity and early experience interact during development as in vertebrates. Here we show, for the first time, that an exposure to predator odour prior to hatching modulates visual lateralization in newly hatched cuttlefish. Only cuttlefish that have been exposed to predator odour display a left-turning bias when tested with blank seawater in a T-shaped apparatus. Exposure to predator odour all the incubation long could appear as an acute predictor of a high-predation surrounding environment. In addition, cuttlefish of all groups display a left-turning preference when tested with predator odour in the apparatus. This suggests the ability of cuttlefish to innately recognize predator odour. To our knowledge, this is the first clear demonstration that lateralization is vulnerable to ecological challenges encountered during embryonic life, and that environmental stimulation of the embryo through the olfactory system could influence the development of subsequent visual lateralization. PMID:23235708

Jozet-Alves, Christelle; Hébert, Marie

2013-01-01

319

Embryonic exposure to predator odour modulates visual lateralization in cuttlefish.  

PubMed

Predation pressure acts on the behaviour and morphology of prey species. In fish, the degree of lateralization varies between high- and low-predation populations. While lateralization appears to be widespread in invertebrates, we do not know whether heredity and early experience interact during development as in vertebrates. Here we show, for the first time, that an exposure to predator odour prior to hatching modulates visual lateralization in newly hatched cuttlefish. Only cuttlefish that have been exposed to predator odour display a left-turning bias when tested with blank seawater in a T-shaped apparatus. Exposure to predator odour all the incubation long could appear as an acute predictor of a high-predation surrounding environment. In addition, cuttlefish of all groups display a left-turning preference when tested with predator odour in the apparatus. This suggests the ability of cuttlefish to innately recognize predator odour. To our knowledge, this is the first clear demonstration that lateralization is vulnerable to ecological challenges encountered during embryonic life, and that environmental stimulation of the embryo through the olfactory system could influence the development of subsequent visual lateralization. PMID:23235708

Jozet-Alves, Christelle; Hébert, Marie

2013-02-01

320

Lateral hyporheic exchange throughout the Mississippi River network  

NASA Astrophysics Data System (ADS)

River water circulates vertically through the river bed and laterally through bank sediments. This hyporheic exchange brings river water into contact with microbes in the adjacent sediments, otherwise known as the hyporheic exchange zone. As such, hyporheic zones act as hotspots for the biogeochemical cycling of carbon, metals and nutrients in rivers, and can, for example, influence the export of nitrogen to downstream ecosystems. Here, we calculate the extent and duration of lateral hyporheic exchange throughout the Mississippi River network, using a physics-based numerical model that takes into account the distribution of groundwater baseflow, river discharge, alluvium permeability and river morphology. We find that in our simulations, lateral exchange occurs throughout the network: practically all of the river water that reaches the mouth of the Mississippi River network has circulated through the lateral hyporheic zone. River water residence time in the hyporheic zone ranges from less than an hour in headwaters to over a month in larger channels. Comparison of the residence times that we derive to a previously reported residence time threshold for denitrification suggests that around one quarter of the lateral hyporheic zones in the Mississippi River network favour denitrification, and thus nitrogen loss. Given that river water can circulate many times through the river bank before reaching the river mouth, and can undergo vertical exchange with the river bed, we suggest that our estimates serve as a lower limit for potential nitrogen loss.

Kiel, Brian A.; Bayani Cardenas, M.

2014-06-01

321

Pericycle Cell Proliferation and Lateral Root Initiation in Arabidopsis1  

PubMed Central

In contrast with other cells generated by the root apical meristem in Arabidopsis, pericycle cells adjacent to the protoxylem poles of the vascular cylinder continue to cycle without interruption during passage through the elongation and differentiation zones. However, only some of the dividing pericycle cells are committed to the asymmetric, formative divisions that give rise to lateral root primordia (LRPs). This was demonstrated by direct observation and mapping of mitotic figures, cell-length measurements, and the histochemical analysis of a cyclin-GUS fusion protein in pericycle cells. The estimated duration of a pericycle cell cycle in the root apical meristem was similar to the interval between cell displacement from the meristem and the initiation of LRP formation. Developmentally controlled LRP initiation occurs early, 3 to 8 mm from the root tip. Thus the first growth control point in lateral root formation is defined by the initiation of primordia in stochastic patterns by cells passing through the elongation and young differentiation zones, up to where lateral roots begin to emerge from the primary root. Therefore, the first growth control point is not restricted to a narrow developmental window. We propose that late LRP initiation is developmentally unrelated to the root apical meristem and is operated by a second growth control point that can be activated by environmental cues. The observation that pericycle cells divide and lateral root primordia form without intervening mitotic quiescence suggests that lateral organ formation in roots and shoots might not be as fundamentally different as previously thought. PMID:11115882

Dubrovsky, Joseph G.; Doerner, Peter W.; Colón-Carmona, Adán; Rost, Thomas L.

2000-01-01

322

An assay for lateral line regeneration in adult zebrafish.  

PubMed

Due to the clinical importance of hearing and balance disorders in man, model organisms such as the zebrafish have been used to study lateral line development and regeneration. The zebrafish is particularly attractive for such studies because of its rapid development time and its high regenerative capacity. To date, zebrafish studies of lateral line regeneration have mainly utilized fish of the embryonic and larval stages because of the lower number of neuromasts at these stages. This has made quantitative analysis of lateral line regeneration/and or development easier in the earlier developmental stages. Because many zebrafish models of neurological and non-neurological diseases are studied in the adult fish and not in the embryo/larvae, we focused on developing a quantitative lateral line regenerative assay in adult zebrafish so that an assay was available that could be applied to current adult zebrafish disease models. Building on previous studies by Van Trump et al. that described procedures for ablation of hair cells in adult Mexican blind cave fish and zebrafish (Danio rerio), our assay was designed to allow quantitative comparison between control and experimental groups. This was accomplished by developing a regenerative neuromast standard curve based on the percent of neuromast reappearance over a 24 hr time period following gentamicin-induced necrosis of hair cells in a defined region of the lateral line. The assay was also designed to allow extension of the analysis to the individual hair cell level when a higher level of resolution is required. PMID:24747778

Pisano, Gina C; Mason, Samantha M; Dhliwayo, Nyembezi; Intine, Robert V; Sarras, Michael P

2014-01-01

323

Laparoscopic repair of recurrent lateral enterocele and rectocele.  

PubMed

It is difficult to determine what types of procedures should be attempted in patients who have recurrent prolapse. We present a case of recurrent lateral enterocele and rectocele after the patient had undergone multiple surgeries for pelvic organ prolapse (POP), including a vaginal hysterectomy, bladder-neck suspension, anterior colporrhaphy, site-specific rectocele repair, apical mesh implant, iliococcygeus vault suspension, and transobturator suburethral sling procedure. With recurrence, the patient underwent robot-assisted laparoscopic sacral colpopexy, tension-free vaginal tape transobturator sling insertion, rectocele repair, and perineorrhaphy with cystoscopy. She then presented with defecatory outlet obstruction and constipation and subsequently was treated with a stapled transanal rectal resection. The patient returned with continued defecatory dysfunction and a recurrent lateral enterocele and rectocele. The recurrence was treated laparoscopically using a lightweight polypropylene mesh. The postoperative period was uneventful. Two years later, the patient reported decreased defecatory symptoms and no further symptomatic prolapse. PMID:25224146

Solomon, Ellen R; Muffly, Tyler M; Hull, Tracy; Paraiso, Marie Fidela R

2015-01-01

324

Extradural Dermoid Cyst Located in the Lateral Sphenoid Ridge  

PubMed Central

Dermoid cysts are rare congenital tumors that occur primarily at the midline at a characteristic intradural location. However, dermoid cysts located at extradural and lateral regions have been rarely reported until now. In the present study, the authors demonstrate the unusual instance of an intracranial extradural dermoid cyst at the lateral sphenoid ridge. A 53-year-old woman admitted because of progressive headache and dizziness. The patient had no neurologic deficits, and magnetic resonance imaging with no contrast enhancement revealed a mass at the right sphenoid ridge. The mass was accompanied with sphenoid bone erosion visible on computed tomography. The patient underwent right pterional craniotomy, and the tumor including the capsule was totally resected. Presence of a dermoid cyst was confirmed with histopathological examination. The patient had no complications during the postoperative period. This study suggests that dermoid cyst should be considered for differential diagnosis of extradural and lateral intracranial masses. PMID:24926471

Ko, Seok-Jin; Park, Kyung-Jae; Park, Dong-Hyuk

2014-01-01

325

Lateral meningocele with asymmetric canal stenosis: A case study  

PubMed Central

Lateral meningocele is a very rare disorder of unknown aetiology typified by the presence of protrusions of the arachnoid and the dura matter extending laterally through inter- or intra-vertebral foramina. We report here the case of a 52-year old male with abnormality of spine when presented with low back pain. The patient did not appear to have any neurological disorder. A computerized tomography (CT) scan was acquired from T12 to mid sacrum with multiplanar reformations. The results showed the presence of a left sided paraspinal cystic lesion projecting from the left neural foramen and extending into the left psoas muscle suggesting a lateral meningocele. In addition, a broad based central and left paracentral disc protrusion was also observed resulting in asymmetric canal stenosis. The patient is on regular follow-up while undergoing palliative treatment. PMID:25561891

Mushtaq, Gohar; Hussain, Iqbal; Khan, Jalaluddin A.; Kamal, Mohammad A.

2014-01-01

326

Management of chronic lateral ankle instability in military service members.  

PubMed

Chronic lateral ankle instability is a condition frequently encountered by orthopedic surgeons treating highly active patient populations, particularly military service members. Providers treating military service members must have a high index of suspicion for this condition when signs and symptoms of functional or mechanical instability exist. Stress testing and ankle MRI, although not definitive in sensitivity for detecting instability or other concomitant injuries, should be considered during the treatment decision-making process. Appropriate nonoperative treatment should be attempted initially; however, when nonoperative treatment fails, surgical management is warranted to prevent untoward long-term sequelae. Proper surgical treatment and subsequent postoperative management are at the discretion of the individual surgeon but must account for the concomitant diseases frequently associated with chronic lateral ankle instability. Low recurrence of lateral instability can be achieved even in high-demand military patient populations with a focused treatment plan. PMID:25280616

Orr, Justin D; Robbins, Justin; Waterman, Brian R

2014-10-01

327

Lateral vibration effects in atomic-scale friction  

SciTech Connect

The influence of lateral vibrations on the stick-slip motion of a nanotip elastically pulled on a flat crystal surface is studied by atomic force microscopy measurements on a NaCl(001) surface in ultra-high vacuum. The slippage of the nanotip across the crystal lattice is anticipated at increasing driving amplitude, similarly to what is observed in presence of normal vibrations. This lowers the average friction force, as explained by the Prandtl-Tomlinson model with lateral vibrations superimposed at finite temperature. Nevertheless, the peak values of the lateral force, and the total energy losses, are expected to increase with the excitation amplitude, which may limit the practical relevance of this effect.

Roth, R. [Climate and Environment Physics, Physics Institute, University of Bern, Bern (Switzerland); Oeschger Centre for Climate Change Research, University of Bern, Bern (Switzerland); Fajardo, O. Y.; Mazo, J. J. [Departamento de Física de la Materia Condensada and Instituto de Ciencia de Materiales de Aragón, CSIC-Universidad de Zaragoza, 50009 Zaragoza (Spain); Meyer, E. [Department of Physics, University of Basel, Klingelbergstrasse 82, 4056 Basel (Switzerland); Gnecco, E. [Instituto Madrileño de Estudios Avanzados en Nanociencia, IMDEA Nanociencia, 28049 Madrid (Spain)

2014-02-24

328

Somatotopy of the lateral line projection in larval zebrafish  

PubMed Central

We examined the topography of the lateral line primary projection in zebrafish larvae by double labeling. The projections of two identified neuromasts of the posterior lateral line are seen as two separate sets of fibers that show reproducible spatial relationships: the projection of the anterior neuromast is always ventrolateral to that of a more posteriorly located neuromast. The same rule applies to the projection of anterior lateral line neuromasts. The position of the neuromasts along the antero posterior axis of the fish therefore is represented in the central projection of the sensory neurons. This somatotopy is similar to, and may be at the origin of, the tonotopic projection of the cochlear hair cells in mammals. PMID:10377454

Alexandre, Daniel; Ghysen, Alain

1999-01-01

329

Strategies of Healthy Adults Walking on a Laterally Oscillating Treadmill  

NASA Technical Reports Server (NTRS)

We mounted a treadmill on top of a six degree-of-freedom motion base platform to investigate locomotor responses produced by healthy adults introduced to a dynamic walking surface. The experiment examined self-selected strategies employed by participants when exposed to continuous, sinusoidal lateral motion of the support surface while walking. Torso translation and step width were used to classify responses used to stabilize gait in a novel, dynamic environment. Two response categories emerged. Participants tended to either fix themselves in space (FIS), allowing the treadbelt to move laterally beneath them, or they fixed themselves to the base (FTB), moving laterally as the motion base oscillated. The degree of fixation in both extremes varied across participants. This finding suggests that normal adults have innate and varied preferences for reacquiring gait stability, some depending more heavily on vision (FIS group) and others on proprioception (FTB group). Keywords: Human locomotion, Unstable surface, Treadmill, Adaptation, Stability

Brady, Rachel A.; Peters, Brian T.; Bloomberg, Jacob J.

2008-01-01

330

Computer simulation of an ideal lateral inhibition function.  

PubMed

A model for lateral inhibition is presented in the context of the auditory channel. The mechanical analyzing system of the inner ear cannot alone account for the frequency resolution of hearing. Some additional mechanism, possibly lateral inhibition located in the auditory neural network, is needed to achieve the frequency selectivity observed in electrophysiological and psychoacoustical experiments. In a computer simulation study, the shape of an ideal lateral inhibition function was obtained. Such a function is applicable to all sensory modalities. In hearing, this function permits the sharpest possible frequency resolution as it can completely remove the frequency desharpening effect of the mechanical properties of the basilar membrane. In vision, it can compensate for abberations caused by the imperfections of the optical system of the eye. PMID:3839141

Rozsypal, A J

1985-01-01

331

Nanoparticle embedded enzymes for improved lateral flow sensors.  

PubMed

In this study, combining the nanoparticle embedded sensors with lateral flow assays, a novel strategy for ensuring the quality of signalling in lateral flow assays (LFAs) was developed. A LFA for reactive oxygen species (ROS) is reported that is based on horse radish peroxidase (HRP) which is co-entrapped with Texas Red dextran inside porous polyacrylamide nanoparticles. In this system, enzymes are protected in the porous matrix of polyacrylamide which freely allows the diffusion of the analyte. The sensor is rapid and sensitive for quantification of hydrogen peroxide concentrations. A test solution of hydrogen peroxides was quantified with this novel LFA-ROS sensor to obtain a linear range between 1 and 25 ?M. Nanoparticle embedding of enzymes is proposed here as a general strategy for developing enzyme-based lateral flow assays, eliminating adverse effects associated with biological samples. PMID:23730687

Özalp, Veli C; Zeydanl?, U?ur S; Lunding, Anita; Kavruk, Murat; Öz, M Tufan; Eyido?an, Füsun; Olsen, Lars F; Öktem, Hüseyin A

2013-08-01

332

Investigating Mechanisms of Lateral Dispersion with a Particle Tracking Model  

NASA Astrophysics Data System (ADS)

A Lagrangian particle tracking model is used to examine lateral mixing dynamics within the thermocline on the shelf of northern Monterey Bay (~20m depth). High-resolution measurements of a complex velocity field from a single ADCP are used to generate a modeled plume to compare against field measurements of a continuously released dye plume. Analysis of the model dye field reveals the importance of vertical shears in horizontal velocities for driving shear flow dispersion processes in the lateral direction. We discuss the role of internal waves as a mechanism for generating some of the observed small-scale vertical variability of the horizontal velocity field and associated lateral dispersion. Finally, we consider horizontal variability in the velocity field by incorporating velocity measurements from a cross-array of nine ADCPs, and we assess the sensitivity of the modeled dispersion to field-derived estimates of vertical diffusivity.

Moniz, R. J.; Monismith, S. G.; Fong, D. A.; Woodson, C. B.; Willis, S. K.

2012-12-01

333

Lateral meningocele with asymmetric canal stenosis: A case study.  

PubMed

Lateral meningocele is a very rare disorder of unknown aetiology typified by the presence of protrusions of the arachnoid and the dura matter extending laterally through inter- or intra-vertebral foramina. We report here the case of a 52-year old male with abnormality of spine when presented with low back pain. The patient did not appear to have any neurological disorder. A computerized tomography (CT) scan was acquired from T12 to mid sacrum with multiplanar reformations. The results showed the presence of a left sided paraspinal cystic lesion projecting from the left neural foramen and extending into the left psoas muscle suggesting a lateral meningocele. In addition, a broad based central and left paracentral disc protrusion was also observed resulting in asymmetric canal stenosis. The patient is on regular follow-up while undergoing palliative treatment. PMID:25561891

Mushtaq, Gohar; Hussain, Iqbal; Khan, Jalaluddin A; Kamal, Mohammad A

2015-01-01

334

Giant negative and positive lateral shifts in graphene superlattices  

NASA Astrophysics Data System (ADS)

Electronic analogy of Goos-Hänchen shift has been well established and investigated in various graphene-based nanostructures, including p-n interface, single and double barriers. In this paper, we have studied the giant negative and positive lateral shifts of the transmitted electron beam through graphene superlattices. It is found that the lateral shifts, depending on the location of new Dirac point, can be negative as well as positive near the band edges of zero-k? (non-Bragg) gap. We have also achieved the enhanced opposite shifts in the graphene superlattice with defect layer, since such structure possesses the defect mode inside the zero-k? gap. The modulations of negative and positive lateral shifts by incidence angles, width and potential height of defect layer may lead to potential applications in the graphene-based electron wave devices.

Chen, Xi; Zhao, Pei-Liang; Lu, Xiao-Jing

2013-05-01

335

Numerical study on lateral movements of cellular flames  

NASA Astrophysics Data System (ADS)

The lateral movements of cellular premixed flames for the Lewis number unity or smaller are studied by means of numerical simulation. The numerical model includes compressibility, viscosity, heat conduction, molecular diffusion, body force, chemical reaction, and convection. We superimpose the disturbances with peculiar wavelengths on the plane flames and calculate the evolution of disturbed flames. When the hydrodynamic and body-force instabilities are dominant (the Lewis number is unity), stationary cellular flames are formed. When the diffusive-thermal instability has a great influence (the Lewis number is smaller than unity), laterally moving cellular flames are obtained. The numerical simulation shows that the Lewis number effect and the nonlinear effect of the flame front are the essential factors in the lateral movements of cellular flames.

Kadowaki, Satoshi

1997-09-01

336

DSMC numerical simulation of lateral jet interaction with rarefied atmosphere  

NASA Astrophysics Data System (ADS)

Hybrid Cartesian grids and surface unstructured triangular cells are used in the DSMC method to simulate lateral jet interaction flow with rarefied atmosphere in transitional regime. The self-adaption of uniform Cartesian grid is conducted according to the local density gradient. The parallel DSMC code is used to compute the lateral jet interaction of a three-dimensional flat plate model on low density wind tunnel test conditions. The results of complex flow field structures, surface flow characteristics and separation lengths agree well with experimental data. The supersonic and hypersonic lateral jet interactions with hypersonic rarefied incoming flow on a slender blunt double-cone are investigated. The effects of flight altitudes, free stream velocities and angles of attack on plume-atmosphere interaction flow fields are numerically analyzed. The influences of parameter distributions with uniform /non-uniform nozzle exit on the separation distance and vortex structure near the jet are simulated in detail.

Liang, Jie; Li, Zhihui; Li, Xuguo; Fang, Ming

2014-12-01

337

Landing adaptations following isolated lateral meniscectomy in athletes  

PubMed Central

Purpose Objective functional outcomes following isolated radial lateral meniscus tears in the athlete between the ages of 14–25 are not clearly defined. The objective of this study was to determine whether patients following lateral meniscectomy demonstrate lower extremity asymmetries relative to control athletes 3 months after surgery. We hypothesized that following lateral meniscectomy, athletes aged 14–25 years old would demonstrate altered landing biomechanics compared to sex, age, height, weight, and sport-matched controls. Methods A total of 18 subjects were included in this study. Nine patients (7 men and 2 women, 20.1 ± 2.8 years) who had undergone first-time isolated radial lateral meniscus tears were tested 3 months following partial lateral meniscectomies and compared to nine sex, age, height, weight, and sport-matched controls (7 men and 2 women, 19.7 ± 3.1 years). A ten-camera motion analysis system and two force platforms were used to collect three trials of bilateral drop landings. A 2X2 ANOVA was used to test the interaction between side (involved vs. uninvolved) and group (patient vs. control). Results The patient group landed with a decreased internal knee extensor moment compared to the uninvolved side and controls (interaction P < 0.05). The involved limb quadriceps isokinetic torque was not decreased compared to the contralateral or control (n.s.). Decreased knee extensor moments were significantly associated with reduced measures of function (IKDC scores: r = 0.69; P < 0.05). Conclusions Athletes who return to sport at approximately 3 months following a partial lateral meniscectomy may employ compensation strategies during landing as evidenced by reduced quadriceps recruitment and functional outcome scores. Clinicians should focus on improving quadriceps function during landing on the involved leg in an attempt to decrease residual limb asymmetries. Level of evidence Case–control study, Level III. PMID:21468616

Minning, Stephen J.; Myer, Gregory D.; Mangine, Robert E.; Colosimo, Angelo J.; Hewett, Timothy E.

2014-01-01

338

Pathophysiological mechanisms of oropharyngeal dysphagia in amyotrophic lateral sclerosis.  

PubMed

We investigated the pathophysiological mechanisms of dysphagia in amyotrophic lateral sclerosis. Forty-three patients with sporadic amyotrophic lateral sclerosis were examined by clinical and electrophysiological methods that objectively measured the oropharyngeal phase of voluntarily initiated swallowing, and these results were compared with those obtained from 50 age-matched control subjects. Laryngeal movements were detected by a piezoelectric sensor and EMG of submental muscles, and needle EMG of the cricopharyngeal muscle of the upper oesophageal sphincter of both the amyotrophic lateral sclerosis and control groups was recorded during swallowing. Amyotrophic lateral sclerosis patients with dysphagia displayed the following abnormal findings. (i) Submental muscle activity of the laryngeal elevators, which produce reflex upward deflection of the larynx during wet swallowing, was significantly prolonged whereas the laryngeal relocation time of the swallowing reflex remained within normal limits. (ii) The cricopharyngeal sphincter muscle EMG demonstrated severe abnormalities during voluntarily initiated swallows. The opening of the sphincter was delayed and/or the closure occurred prematurely, the total duration of opening was shortened and, at times, unexpected motor unit bursts appeared during this period. (iii) During voluntarily initiated swallows there was significant lack of co-ordination between the laryngeal elevator muscles and the cricopharyngeal sphincter muscle. These results point to two pathophysiological mechanisms that operate to cause dysphagia in amyotrophic lateral sclerosis patients. (i) The triggering of the swallowing reflex for the voluntarily initiated swallow is delayed and eventually abolished, whereas the spontaneous reflexive swallows are preserved until the preterminal stage of amyotrophic lateral sclerosis. (ii) The cricopharyngeal sphincter muscle of the upper oesophageal sphincter becomes hyper-reflexic and hypertonic. As a result, the laryngeal protective system and the bolus transport system of deglutition lose their co-ordination during voluntarily initiated swallowing. We conclude that these pathophysiological changes are related mainly to the progressive degeneration of the excitatory and inhibitory corticobulbar pyramidal fibres. PMID:10611127

Ertekin, C; Aydogdu, I; Yüceyar, N; Kiylioglu, N; Tarlaci, S; Uludag, B

2000-01-01

339

Intubating laryngeal mask airway as an independent ventilatory and intubation device. A comparison between supine, right lateral and left lateral  

PubMed Central

Background Sudden loss of airway in patients in the lateral position has always been proven to be difficult to manage with conventional laryngoscopy. We performed a randomized controlled trial to prove the success rate of ventilation and intubation in the lateral position via intubating laryngeal mask airway (ILMA). Methods Ninety patients were divided into three groups of 30 patients each, positioned supine, right lateral, and left lateral randomly. Each group comprised of both sexes of American Society of Anesthesiologists grade I and II, aged between 18-55 years with normal airway posted for surgery under general anesthesia. Patients were pre-medicated with fentanyl followed by induction with propofol and neuromuscular blockade with rocuronium. ILMA was inserted and blind tracheal intubation via ILMA was done. The success rate, time taken and the number of adjusting maneuvers used for both procedures were recorded. The data was tabulated and analyzed using ANOVA (analysis of variance), multiple 't' test and chi square. Results The success rate of intubation (96%) and time taken in insertion and intubation was found to be quite similar in all the three groups. Conclusions We conclude that the ILMA has an important role to play in the emergency management of airways in patients in the lateral position in terms of ease, success rate and time taken. PMID:24228142

Bharadwaj, Avnish; Chauhan, Gaurav; Kalita, Drubajyoti

2013-01-01

340

Lateral flow microarrays: a novel platform for rapid nucleic acid detection based on miniaturized lateral flow chromatography  

PubMed Central

Widely used nucleic acid assays are poorly suited for field deployment where access to laboratory instrumentation is limited or unavailable. The need for field deployable nucleic acid detection demands inexpensive, facile systems without sacrificing information capacity or sensitivity. Here we describe a novel microarray platform capable of rapid, sensitive nucleic acid detection without specialized instrumentation. The approach is based on a miniaturized lateral flow device that makes use of hybridization-mediated target capture. The miniaturization of lateral flow nucleic acid detection provides multiple advantages over traditional lateral flow devices. Ten-microliter sample volumes reduce reagent consumption and yield analyte detection times, excluding sample preparation and amplification, of <120?s while providing sub-femtomole sensitivity. Moreover, the use of microarray technology increases the potential information capacity of lateral flow. Coupled with a hybridization-based detection scheme, the lateral flow microarray (LFM) enables sequence-specific detection, opening the door to highly multiplexed implementations for broad-range assays well suited for point-of-care and other field applications. The LFM system is demonstrated using an isothermal amplification strategy for detection of Bacillus anthracis, the etiologic agent of anthrax. RNA from as few as two B. anthracis cells was detected without thermocycling hardware or fluorescence detection systems. PMID:17478499

Carter, Darren J.; Cary, R. Bruce

2007-01-01

341

Released micromachined beams utilizing laterally uniform porosity porous silicon  

PubMed Central

Suspended micromachined porous silicon beams with laterally uniform porosity are reported, which have been fabricated using standard photolithography processes designed for compatibility with complementary metal-oxide-semiconductor (CMOS) processes. Anodization, annealing, reactive ion etching, repeated photolithography, lift off and electropolishing processes were used to release patterned porous silicon microbeams on a Si substrate. This is the first time that micromachined, suspended PS microbeams have been demonstrated with laterally uniform porosity, well-defined anchors and flat surfaces. PACS 81.16.-c; 81.16.Nd; 81.16.Rf PMID:25221457

2014-01-01

342

LATERAL GENE TRANSFER AND THE HISTORY OF BACTERIAL GENOMES  

SciTech Connect

The aims of this research were to elucidate the role and extent of lateral transfer in the differentiation of bacterial strains and species, and to assess the impact of gene transfer on the evolution of bacterial genomes. The ultimate goal of the project is to examine the dynamics of a core set of protein-coding genes (i.e., those that are distributed universally among Bacteria) by developing conserved primers that would allow their amplification and sequencing in any bacterial taxa. In addition, we adopted a bioinformatic approach to elucidate the extent of lateral gene transfer in sequenced genome.

Howard Ochman

2006-02-22

343

Lateral variation of target poisoning during reactive magnetron sputtering  

SciTech Connect

The reactive gas incorporation into a Ti sputter target has been investigated using laterally resolving ion beam analysis during dc magnetron deposition of TiN in an Ar/N{sub 2} atmosphere. At sufficiently low reactive gas flow, the nitrogen incorporation exhibits a pronounced lateral variation, with a lower areal density in the target racetrack compared to the target center and edge. The findings are reproduced by model calculations. In the racetrack, the balance of reactive gas injection and sputter erosion is shifted toward erosion. The injection of nitrogen is dominated by combined molecular adsorption and recoil implantation versus direct ion implantation.

Guettler, D.; Groetzschel, R.; Moeller, W. [Institute of Ion Beam Physics and Materials Research, Forschungszentrum Dresden-Rossendorf, P.O. Box 510119, 01314 Dresden (Germany)

2007-06-25

344

Lateral beam collimation of a phased array semiconductor laser  

SciTech Connect

The lateral near-field and far-field radiation patterns of a phase-locked array of gain-guided semiconductor injection lasers are studied. These lasers exhibit a lateral far-field beam divergence full width at half-maximum (FWHM) of 1.5/sup 0/ up to 200 mW of output power per facet. Greater than 60% of the laser output power is concentrated in a low divergence beam at this high optical power. Catastrophic mirror degradation of the laser occurs at roughly-equal250--270 mW cw per facet.

Scifres, D.; Burnham, R.D.; Streifer, W.; Bernstein, M.

1982-10-01

345

Laterality in coiling behaviour of snakes: another interpretation.  

PubMed

The direction of coiling was periodically recorded for two species of viperid snakes--copperheads (Agkistrodon contortrix) and cottonmouths (Agkistrodon piscivorus). Overall, neither species showed a significant preference for coiling in a particular direction. Only 1 of 22 snakes exhibited an individual preference, a result within expectation for random direction of coiling when using a 5% rejection level for statistical testing. A previously published claim for laterality in coiling direction by cottonmouths presented similar results but came to the opposite conclusion. The data from the combined studies suggest that if laterality in coiling direction does occur, it is extremely weak and inconsistent. PMID:17852698

Heatwole, Harold; King, Peter; Levine, Samuel G

2007-11-01

346

An Improved Method of Manufacturing Corrugated Boxes: Lateral Corrugator  

SciTech Connect

Paper physicists have known that a corrugated box constructed from outer liner sheets having a predominant fiber orientation aligned with the corrugating flute direction would have higher stiffness and crush resistance (per unit of fiber weight) than the conventional box construction. Such increased performance per unit of fiber weight could result in fiber reduction and energy savings for boxes having equivalent performance specifications. The goal of this project was to develop and demonstrate a commercially viable lateral corrugating process. This included designing and building a pilot lateral corrugator, testing and evaluating pilot machine made boxes, and developing a strategy for commercialization.

Frank C. Murray Ph.D.; , Roman Popil Ph.D.; Michael Shaepe (formerly with IPST, now at Cargill. Inc)

2008-12-18

347

Lateral flow biosensors for the detection of nucleic acid.  

PubMed

The detection of nucleic acid is of central importance for the diagnosis of genetic diseases, infectious agents, and biowarfare agents. Traditional strategies and technologies for nucleic acid detection are time-consuming and labor-intensive. Recently, isothermal strand-displacement reaction-based lateral flow biosensors have attracted a great deal of research interest because they are sensitive, simple, fast, and easy to use. Here, we describe a lateral flow biosensor based on isothermal strand-displacement polymerase reaction and gold nanoparticles for the visual detection of nucleic acid. PMID:24026695

Zeng, Lingwen; Lie, Puchang; Fang, Zhiyuan; Xiao, Zhuo

2013-01-01

348

Two blowing concepts for roll and lateral control of aircraft  

NASA Technical Reports Server (NTRS)

Two schemes to modulate aerodynamic forces for roll and lateral control of aircraft have been investigated. The first scheme, called the lateral blowing concept, consists of thin jets of air exiting spanwise, or at small angle with the spanwise direction, from slots at the tips of straight wings. For this scheme, in addition to experimental measurements, a theory was developed showing the analytical relationship between aerodynamic forces and jet and wing parameters. Experimental results confirmed the theoretically derived scaling laws. The second scheme, which was studied experimentally, is called the jet spoiler concept and consists of thin jets exiting normally to the wing surface from slots aligned with the spanwise direction.

Tavella, D. A.; Wood, N. J.; Lee, C. S.; Roberts, L.

1986-01-01

349

76 FR 78823 - Schedule for Rating Disabilities; Evaluation of Amyotrophic Lateral Sclerosis  

Federal Register 2010, 2011, 2012, 2013, 2014

...criterion for amyotrophic lateral sclerosis (ALS) in the VA Schedule...from the Amyotrophic Lateral Sclerosis Association. The comments...the Amyotrophic Lateral Sclerosis (ALS) Association strongly...proposed rule would ``rate multiple disabilities as a...

2011-12-20

350

38 CFR 3.318 - Presumptive service connection for amyotrophic lateral sclerosis.  

Code of Federal Regulations, 2010 CFR

...Presumptive service connection for amyotrophic lateral sclerosis. 3.318 Section 3.318...Presumptive service connection for amyotrophic lateral sclerosis. (a) Except as provided...section, the development of amyotrophic lateral sclerosis manifested at any time...

2010-07-01

351

The effects of torsional-lateral coupling on the dynamics of a gear coupled rotor  

E-print Network

This thesis focuses on the torsional-lateral interactions seen in gear coupled rotors. Of particular interest are cases where the torsional stiffness parameters affect the lateral critical speeds and where lateral stiffness and damping parameters...

Emery, Michael Aaron

2007-04-25

352

Analytical model for silicon-on-insulator lateral high-voltage devices using variation of lateral thickness technique  

NASA Astrophysics Data System (ADS)

Recently, the variation of lateral thickness (VLT) technique has been proposed as an effective lateral voltage-sustaining technology. However, no analytical model has been reported for exploring the physical mechanism quantitatively. By solving the two-dimensional (2D) Poisson equation, an analytical model for a silicon-on-insulator (SOI) device with a VLT structure is proposed in this paper to optimize the surface potential and electric field distribution of the VLT SOI device. The lateral and vertical breakdown voltages are formulized to quantify the breakdown characteristic. The drift doping concentration range is derived to maximize the breakdown voltage. This model is used to investigate the electric field distribution and breakdown voltage of the VLT SOI device with various parameters. The validity of the proposed model is verified by the fair agreement between the analytical and numerical results.

Yao, Jiafei; Guo, Yufeng; Li, Man; Huang, Xiaofeng; Lin, Hong; Ji, Xincun; Xu, Yue

2015-02-01

353

Direction selectivity in the middle lateral and lateral (ML and L) visual areas in the California ground squirrel.  

PubMed

Extracellular recordings obtained from the extrastriate cortex of the California ground squirrel, a diurnal sciurid, show that large receptive fields and a strong direction selectivity are present in the middle lateral area (ML) and the lateral area (L), located laterally to V2 and V3. Direction selectivity was tested by presenting stimuli of varying dimensions, shapes and speeds at different locations in the visual field. Most cells in ML and L (84%) were direction selective, with a preference for fast speeds, indicating that these areas share a role in motion processing. Areas ML and L may be homologous to area MT or may represent a case of homoplasia. A directional anisotropy for motion towards the vertical meridian was found in ML and L cells, suggesting that these areas may be involved in detecting predators and other moving objects coming from the periphery, rather than in processing flow fields caused by forward locomotion, for which a centrifugal bias might be expected. PMID:9651131

Paolini, M; Sereno, M I

1998-06-01

354

Ligand-dependent Notch signaling strength orchestrates lateral induction and lateral inhibition in the developing inner ear.  

PubMed

During inner ear development, Notch exhibits two modes of operation: lateral induction, which is associated with prosensory specification, and lateral inhibition, which is involved in hair cell determination. These mechanisms depend respectively on two different ligands, jagged 1 (Jag1) and delta 1 (Dl1), that rely on a common signaling cascade initiated after Notch activation. In the chicken otocyst, expression of Jag1 and the Notch target Hey1 correlates well with lateral induction, whereas both Jag1 and Dl1 are expressed during lateral inhibition, as are Notch targets Hey1 and Hes5. Here, we show that Jag1 drives lower levels of Notch activity than Dl1, which results in the differential expression of Hey1 and Hes5. In addition, Jag1 interferes with the ability of Dl1 to elicit high levels of Notch activity. Modeling the sensory epithelium when the two ligands are expressed together shows that ligand regulation, differential signaling strength and ligand competition are crucial to allow the two modes of operation and for establishing the alternate pattern of hair cells and supporting cells. Jag1, while driving lateral induction on its own, facilitates patterning by lateral inhibition in the presence of Dl1. This novel behavior emerges from Jag1 acting as a competitive inhibitor of Dl1 for Notch signaling. Both modeling and experiments show that hair cell patterning is very robust. The model suggests that autoactivation of proneural factor Atoh1, upstream of Dl1, is a fundamental component for robustness. The results stress the importance of the levels of Notch signaling and ligand competition for Notch function. PMID:24821984

Petrovic, Jelena; Formosa-Jordan, Pau; Luna-Escalante, Juan C; Abelló, Gina; Ibañes, Marta; Neves, Joana; Giraldez, Fernando

2014-06-01

355

Commensurability Oscillations in the Radio-Frequency Conductivity of Unidirectional Lateral Superlattices  

E-print Network

the rf magnetoconductivity of unidirectional lateral superlattices (ULSLs) by detecting the attenuation,13) In the present study, we measure, employing the CPW method, rf magnetoconductivity of unidirectional lateral

Katsumoto, Shingo

356

Current hypotheses for the underlying biology of amyotrophic lateral sclerosis  

Microsoft Academic Search

The mechanisms involved in selective motor neuron degeneration in amyotrophic lateral sclerosis remain unknown more than 135 years after the disease was first described. Although most cases have no known cause, mutations in the gene encoding Cu\\/Zn superoxide dismutase (SOD1) have been implicated in a fraction of familial cases of the disease. Transgenic mouse models with mutations in the SOD1

Jeffrey D. Rothstein

2009-01-01

357

Trajectory Planning and Lateral Control for Agricultural Guidance Applications  

E-print Network

, the lateral controller which was used to calculate the steering angle is described and the method how although they are very successful on the market. Weak spots are that the localization robustness depends on a laser scanner was de- veloped during the last two years. To steer the tractor and the implement

Berns, Karsten

358

Impaired Structural Motor Connectome in Amyotrophic Lateral Sclerosis  

Microsoft Academic Search

Amyotrophic lateral sclerosis (ALS) is a severe neurodegenerative disease selectively affecting upper and lower motor neurons. Patients with ALS suffer from progressive paralysis and eventually die on average after three years. The underlying neurobiology of upper motor neuron degeneration and its effects on the complex network of the brain are, however, largely unknown. Here, we examined the effects of ALS

Esther Verstraete; Jan H. Veldink; Rene C. W. Mandl; Leonard H. van den Berg; Martijn P. van den Heuvel

2011-01-01

359

Lateral sinus thrombosis associated with zoster sine herpete  

Microsoft Academic Search

Herpes zoster results from reactivation of the varicella zoster virus (VZV). Zoster sine herpete (ZSH) is an uncommon manifestation of VZV infection and presents with similar symptoms but without the vesicular rash. We describe an unusual case of lateral sinus thrombosis (LST) that developed during the clinical course of ZSH in the C2 distribution. A 55-year-old woman presented with a

James Chan; Richard T. Bergstrom; Donald C. Lanza; John G. Oas

2004-01-01

360

Controller design for improving lateral vehicle dynamic stability  

Microsoft Academic Search

A vehicle dynamics control system has been developed in this study for improving vehicle dynamic stability under critical lateral motions. The system consists of a feedforward controller, a state feedback controller, and an estimator for the body sideslip angle. The linear quadratic regulator theory has been exploited for the state feedback gain, and for estimation of the body sideslip angle,

Seung-Jin Heo; Inho Baek

2001-01-01

361

Percutaneous endoscopic gastrostomy and enteral nutrition in amyotrophic lateral sclerosis  

Microsoft Academic Search

Bulbar involvement in amyotrophic lateral sclerosis (ALS) is often related to a worse prognosis on account of the higher risk of pulmonary aspiration and undernutrition due to dysphagia. The aim of our study was to assess the effects of enteral feeding by percutaneous endoscopic gastrostomy (PEG) in a long-term follow-up of ALS patients. We report the results of PEG in

L. Mazzini; T. Corrà; M. Zaccala; G. Mora; M. Piano; M. Galante

1995-01-01

362

Lateral internal sphincterotomy under local anesthesia (randomized clinical trial)  

Microsoft Academic Search

Summary  BACKGROUND: Today there is an attempt to perform Lateral Internal Sphincterotomy (LIS) operation on an ambulatory basis under local anesthesia. This study aimed to compare postoperative outcome in local anesthesia with spinal anesthesia. METHODS: Design: randomized, double blinded, controlled trial. 62 patients were randomly divided into group A (local anesthesia) and group B (spinal anesthesia) with n = 31 equally.

S. Mohsen Towliat Kashani; Mohebi Hasan Ali; Lak Marzie; Ziaee S. Ali

2006-01-01

363

Laterally stacked Schottky diodes for infrared sensor applications  

NASA Technical Reports Server (NTRS)

Laterally stacked Schottky diodes for infrared sensor applications are fabricated utilizing porous silicon having pores. A Schottky metal contract is formed in the pores, such as by electroplating. The sensors may be integrated with silicon circuits on the same chip with a high quantum efficiency, which is ideal for IR focal plane array applications due to uniformity and reproducibility.

Lin, True-Lon (inventor)

1991-01-01

364

Preverbal Sexual Abuse: What Two Children Report in Later Years.  

ERIC Educational Resources Information Center

Two case studies are presented of preverbal sexual abuse in which children later gave detailed accounts of their abuse, indicating that their memories were still intact despite lacking sufficient language to report the abuse when it occurred. A series of issues about preverbal abuse are discussed while integrating cognitive-developmental research…

Hewitt, Sandra K.

1994-01-01

365

Quality of life in childhood epilepsy with lateralized epileptogenic foci  

Microsoft Academic Search

BACKGROUND: Measuring quality of life (QOL) helps to delineate mechanisms underlying the interaction of disease and psychosocial factors. In adults, epileptic foci in the left temporal lobe led to lower QOL and higher depression and anxiety as compared to the right-sided foci. No study addressed the development of QOL disturbances depending on the lateralization of epileptogenic focus. The objective of

Krystyna A. Mathiak; Ma?gorzata ?uba; Klaus Mathiak; Katarzyna Karzel; Tomasz Wola?czyk; El?bieta Szczepanik; Pawe? Ostaszewski

2010-01-01

366

Optically controlled lateral PIN diodes and microwave control circuits  

Microsoft Academic Search

The fabrication, testing and application of lateral PIN diodes in optically controlled microwave circuits are summarized. Complete static parameterization under various optical conditions is described. The diodes have breakdown voltages of up to 200 V, capacitances as low as 0.1 pF, and an increase in capacitance of over thirty times when illuminated with a semiconductor laser diode. Optically excited microwave

Paul J. Stabile; Arye Rosen; P. R. Herczfeld

1986-01-01

367

Characterizing lateral resolution of interferometers: the Height Transfer Function (HTF)  

Microsoft Academic Search

The lateral resolution of an interferometer is limited mainly by the design of the optical arrangement as well as the size of the beam stop. For its characterization the MTF1,2 is not very useful. The height of a structure normal to the surface under test is transferred into a phase of a reflected wavefront. Since imaging mechanisms for intensity and

B. Doerband; J. Hetzler

2005-01-01

368

Lateral moraine age in Park Valley, Tararua Range, New Zealand  

Microsoft Academic Search

Recent geomorphologie and sedimentologic investigations in Park Valley, in the central Tararua Range, have identified several landforms of glacial erosion and deposition, including cirque basins, a U?shaped glacial valley, and a lateral moraine ridge. The presence of Kawakawa tephra (Aokautere Ash) within loess c. 50 cm beneath the surface of the moraine has indicated that the moraine was formed prior

Martin S. Brook

2009-01-01

369

Ratchet effects in graphene and quantum wells with lateral superlattice  

NASA Astrophysics Data System (ADS)

Theoretical and experimental studies on the ratchet effects in graphene and in quantum wells with a lateral superlattice excited by alternating electric fields of terahertz frequency range are presented. We discuss the Seebeck ratchet effect and helicity driven photocurrents and show that the photocurrent generation is based on the combined action of a spatially periodic in-plane potential and a spatially modulated light.

Golub, L. E.; Nalitov, A. V.; Ivchenko, E. L.; Olbrich, P.; Kamann, J.; Eroms, J.; Weiss, D.; Ganichev, S. D.

2013-12-01

370

The joint development of hemispheric lateralization for words and faces.  

PubMed

Consistent with long-standing findings from behavioral studies, neuroimaging investigations have identified a region of the inferior temporal cortex that, in adults, shows greater face selectivity in the right than left hemisphere and, conversely, a region that shows greater word selectivity in the left than right hemisphere. What has not been determined is how this pattern of mature hemispheric specialization emerges over the course of development. The present study examines the hemispheric superiority for faces and words in children, young adolescents and adults in a discrimination task in which stimuli are presented briefly in either hemifield. Whereas adults showed the expected left and right visual field superiority for face and word discrimination, respectively, the young adolescents demonstrated only the right-field superiority for words and no field superiority for faces. Although the children's overall accuracy was lower than that of the older groups, like the young adolescents, they exhibited a right visual field superiority for words but no field superiority for faces. Interestingly, the emergence of face lateralization was correlated with reading competence, measured on an independent standardized test, after regressing out age, quantitative reasoning scores, and face discrimination accuracy. Taken together, these findings suggest that the hemispheric organization of face and word recognition do not develop independently and that word lateralization, which emerges earlier, may drive later face lateralization. A theoretical account in which competition for visual representations unfolds over the course of development is proposed to account for the findings. PMID:22866684

Dundas, Eva M; Plaut, David C; Behrmann, Marlene

2013-05-01

371

Platelet Serotonin Level Predicts Survival in Amyotrophic Lateral Sclerosis  

E-print Network

Platelet Serotonin Level Predicts Survival in Amyotrophic Lateral Sclerosis Luc Dupuis1,2 *, Odile. Methodology: Platelet and plasma unconjugated concentrations of serotonin and plasma 5-HIAA, the major: Platelet serotonin levels were significantly decreased in ALS patients. Platelet serotonin levels did

Paris-Sud XI, Université de

372

Integration of emotion and cognition in the lateral prefrontal cortex  

E-print Network

Integration of emotion and cognition in the lateral prefrontal cortex Jeremy R. Gray*, Todd S for review July 23, 2001) We used functional MRI to test the hypothesis that emotional states can selectively for an integration of emotion and cognition. Participants (n 14) watched short videos intended to induce emotional

373

Early Speech Perception and Later Language Development: Implications for the \\  

Microsoft Academic Search

In this article, we present a summary of recent research linking speech perception in infancy to later language development, as well as a new empirical study examining that linkage. Infant phonetic discrimination is initially language universal, but a de- cline in phonetic discrimination occurs for nonnative phonemes by the end of the 1st year. Exploiting this transition in phonetic perception

Patricia K. Kuhl; Barbara T. Conboy; Denise Padden; Tobey Nelson; Jessica Pruitt

2005-01-01

374

Morality, Slavery and the Jurists in the Later Roman Republic  

Microsoft Academic Search

The problem I wish to discuss is the moral attitude of the later Republican jurists to slavery. The prominent jurists of the time belong to the upper classes and, although it would be wrong to generalize from the jurists to other members of the aristocracy, we shall have a certain glimpse into the social attitudes of the period if we

Alan Watson

1968-01-01

375

Unsatisfactory answers: Dialogism in George Eliot's later novels  

Microsoft Academic Search

George Eliot's later novels are discussed with reference to Mikhail Bakhtin's concept of dialogism. Although Bakhtin traces dialogism from comedy and carnival, Eliot's dialogism is rooted in tragedy. Romola is set during Florentine carnival and Savonarola's sacred parody of carnival. While Eliot and Bakhtin, following Goethe, both use carnival as an image of ambivalence, in contrast to Bakhtin, Eliot recognizes

Hilda Margaret Hollis

1998-01-01

376

Unsatisfactory Answers: Dialogism in George Eliot's Later Novels  

Microsoft Academic Search

George Eliot's later novels are discussed with reference to Mikhail Bakhtin's concept of dialogism. Although Bakhtin traces dialogism from comedy and carnival, Eliot's dialogism is rooted in tragedy. Romola is set during Florentine carnival and Savonarola's sacred parody of carnival. While Eliot and Bakhtin, following Goethe, both use carnival as an image of ambivalence, in contrast to Bakhtin, Eliot recognizes

Hilda Hollis

1998-01-01

377

Turing Test: 50 Years Later AYSE PINAR SAYGIN1  

E-print Network

mathematician Alan Turing1 proposed the Turing Test (TT) as a replacement for the question "Can machines thinkTuring Test: 50 Years Later AYSE PINAR SAYGIN1 , ILYAS CICEKLI2 & VAROL AKMAN2 1Department-mail: ilyas@cs.bilkent.edu.tr; akman@cs.bilkent.edu.tr Abstract. The Turing Test is one of the most disputed

Duygulu-Sahin, Pinar

378

Imaging studies on sex differences in the lateralization of language  

Microsoft Academic Search

It has been proposed that language is more strongly lateralized in males than in females. Recent imaging studies, however, have yielded a variety of seemingly contradictory observations. Here, we categorize these observations into three groups: (1) studies that employed sub-lexical tasks applicable to nonwords, which found sex-differences in the anterior language areas; (2) studies that employed tasks applicable to real

Kenji Kansaku; Shigeru Kitazawa

2001-01-01

379

Spatiotemporal Coupling of the Tongue in Amyotrophic Lateral Sclerosis  

ERIC Educational Resources Information Center

Purpose: The primary aim of the investigation was to identify deficits in spatiotemporal coupling between tongue regions in amyotrophic lateral sclerosis (ALS). The relations between disease-related changes in tongue movement patterns and speech intelligibility were also determined. Methods: The authors recorded word productions from 11…

Kuruvilla, Mili S.; Green, Jordan R.; Yunusova, Yana; Hanford, Kathy

2012-01-01

380

Tuning the lateral mobility of thin block copolymer films  

NASA Astrophysics Data System (ADS)

Polymer mobility in confined environments is of both theoretical and practical interest. The controlled formation and characterization of systems where such effects can be studied remain active areas of investigation. In this work, we created ultrathin (< 50 nm) supported films of amphiphilic polybutylene-poly(ethylene) oxide diblock copolymers, through Langmuir-Blodgett and Langmuir-Schaefer techniques. To adjust the lateral mobility of these ultrathin films, short polyisobutylene homopolymer was introduced during the film assembly process. Preliminary fluorescence recovery after photobleaching (FRAP) results show that the lateral mobility of the block copolymers is proportional to the logarithm of homopolymer concentration. The mobility can be varied by up to a factor of 8 with as little as 1 mol% of homopolymer. The role of the added homopolymer on the block copolymer lateral mobility is likely to be related with several features such as chain entanglements, interfacial constraints, and interlayer friction. By varying the concentration and the molecular weight of the homopolymer introduced into the films, we attempt to explain the underlying physical mechanisms that are responsible for changes in lateral mobility.

Bermudez, Harry; Kourouklis, Andreas

2013-03-01

381

Lateral variations near the core-mantle boundary  

Microsoft Academic Search

Amplitude behavior and differential travel times between S and SKS and between SKKS and SKS have been used to investigate lateral variations at the core-mantle boundary. Data were obtained from source regions in South America and the Fiji-Tonga area. It is found that SKS and S are anomalously separated by up to 8 seconds, and that SKS and SKKS are

Edward Garnero; Donald Helmberger; Gladys Engen

1988-01-01

382

Modeling, Simulation, and Parameter Estimation of Lateral Spacecraft Fuel Slosh  

NASA Technical Reports Server (NTRS)

Predicting the effect of fuel slosh on a spacecraft and/or launch vehicle attitude control system is a very important and a challenging task. Whether the spacecraft is under spinning or lateral moving conditions, the dynamic effect of the fuel slosh will help determine whether the spacecraft will remain on its chosen trajectory. There are three categories of slosh that can be caused by launch vehicle and/or spacecraft maneuvers when the fuel is in the presence of an acceleration field. These include bulk fluid motion, subsurface wave motion, and free surface slosh. Each of these slosh types have a periodic component that is defined by either a spinning or lateral motion. For spinning spacecraft, all three types of slosh can play a major role in determining stability. Bulk fluid motion and free surface slosh can affect the lateral slosh characteristics. For either condition, the possibility for an unpredicted coupled resonance between the spacecraft and its on board fuel can have mission threatening affects. This on-going research effort aims at improving the accuracy and efficiency of modeling techniques used to predict these types of lateral fluid motions. In particular, efforts will focus on analyzing the effects of viscoelastic diaphragms on slosh dynamics.

Chatman, Yadira; Gangadharan, Sathya; Marsell, Brandon; Schlee, Keith; Sudermann, James; Walker, Charles; Ristow, James

2008-01-01

383

Nursery school personality and political orientation two decades later  

Microsoft Academic Search

The present study reports on the personality attributes of nursery school children who two decades later were reliably stratiWed along a liberal\\/conservative dimension. An unprecedented ana- lytical opportunity existed to evaluate how the political views of these young adults related to assess- ments of them when in nursery school, prior to their having become political beings. Preschool children who 20

Jack Block; Jeanne H. Block

2005-01-01

384

Lateral Approach to the Hook of Hamate for its Fracture  

Microsoft Academic Search

We have recently experienced one case of the fracture of the hook of the hamate that was diagnosed only by the CT scan. As a surgical approach, lateral approach to the hook of the hamate for its fracture was utilized. We found that this approach was safe, easy and quick.

TAKAYA MIZUSEKI; YOSHIKAZU IKUTA; TSUNEJI MURAKAMI; SADAO WATARI

1986-01-01

385

Lateral approach to the hook of hamate for its fracture.  

PubMed

We have recently experienced one case of the fracture of the hook of the hamate that was diagnosed only by the CT scan. As a surgical approach, lateral approach to the hook of the hamate for its fracture was utilized. We found that this approach was safe, easy and quick. PMID:3958528

Mizuseki, T; Ikuta, Y; Murakami, T; Watari, S

1986-02-01

386

Astronomy & Astrophysics manuscript no. (will be inserted by hand later)  

E-print Network

be attributed to various hydrodynamic and hydromagnetic instabilities that can arise in differentially rotatingAstronomy & Astrophysics manuscript no. (will be inserted by hand later) The stability of Physics and Technology, 194021 St. Petersburg, Russia January 28, 2005 Abstract. The stability properties

387

Molecular biology of amyotrophic lateral sclerosis: insights from genetics  

Microsoft Academic Search

Amyotrophic lateral sclerosis (ALS) is a paralytic disorder caused by motor neuron degeneration. Mutations in more than 50 human genes cause diverse types of motor neuron pathology. Moreover, defects in five Mendelian genes lead to motor neuron disease, with two mutations reproducing the ALS phenotype. Analyses of these genetic effects have generated new insights into the diverse molecular pathways involved

Piera Pasinelli; Robert H. Brown

2006-01-01

388

Multiple Timescales of Memory in Lateral Habenula and Dopamine Neurons  

E-print Network

Neuron Article Multiple Timescales of Memory in Lateral Habenula and Dopamine Neurons Ethan S of their reward memory and the factors that control its timescale. Here we recorded from dopamine neurons, as well memory expressed when a future reward outcome was revealed. The short- and long-time- scale memories were

Nakahara, Hiroyuki

389

Language Lateralization in Children Using Functional Transcranial Doppler Sonography  

ERIC Educational Resources Information Center

Aim: Language lateralization with functional transcranial Doppler sonography (fTCD) and lexical word generation has been shown to have high concordance with the Wada test and functional magnetic resonance imaging in adults. We evaluated a nonlexical paradigm to determine language dominance in children. Method: In 23 right-handed children (12…

Haag, Anja; Moeller, Nicola; Knake, Susanne; Hermsen, Anke; Oertel, Wolfgang H.; Rosenow, Felix; Hamer, Hajo M.

2010-01-01

390

Lateral inhibition of Notch signaling in neoplastic cells.  

PubMed

During normal development, heterogeneous expression of Notch ligands can result in pathway suppression in the signal-sending cell, a process known as lateral inhibition. It is unclear if an analogous phenomenon occurs in malignant cells. We observed significant induction of Notch ligands in glioblastoma neurospheres and pancreatic carcinoma cells cultured in low oxygen, suggesting that this phenomenon could occur around hypoxic regions. To model lateral inhibition in these tumors, the ligand Jagged1 was overexpressed in glioblastoma and pancreatic carcinoma cells, resulting in overall induction of pathway targets. However, when ligand high and ligand low cells from a single line were co-cultured and then separated, we noted suppression of Notch pathway targets in the former and induction in the latter, suggesting that neoplastic lateral inhibition can occur. We also found that repression of Notch pathway targets in signal-sending cells may occur through the activity of a Notch ligand intracellular domain, which translocates into the nucleus. Understanding how this neoplastic lateral inhibition process functions in cancer cells may be important in targeting ligand driven Notch signaling in solid tumors. PMID:25557173

Lim, Kah Jing; Brandt, William D; Heth, Jason A; Muraszko, Karin M; Fan, Xing; Bar, Eli E; Eberhart, Charles G

2015-01-30

391

The chemical receptive mechanism in the lateral-line organ.  

PubMed

Stimulating effects of various mono- and divalent cations on the lateral-line organ were theoretically analysed by use of the site binding chemical adsorption model with the principle of "hard and soft acids and bases." A linear relation between the softness parameter and the logarithmic value of the intrinsic association constant was obtained for the cations of Na, K, Tl, Ag, Ca, Mg, and Cd. The order of effectiveness of these cations agreed with that of the intrinsic association constant. Using these values for various cations, the critical concentration of divalent cations necessary to supress the effect of monovalent cations was calculated and compared with the experimental values. The calculated concentration of the hard divalent cations (Ca2+, Mg2+), which suppressed the effect of the hard monovalent cations (K+, Na+), agreed with the experimental concentration. The same relations were obtained between the suppressive effect of a soft divalent and a soft monovalent cation. The chemical adsorption of Ag+ on the lateral-line organ of Xenopus laevis was investigated by using a transmission electron microscope equipped with an X-ray microprobe analyser in order to get further confirmation of this model. Silver applied to the lateral-line organ was found around a kinocilium but not in the hair cells of the lateral-line organ. Thus chemical adsorption of the cation on the surface of the receptor membrane was directly proved. PMID:739683

Yoshioka, T; Asanuma, A; Yanagisawa, K; Katsuki, Y

1978-01-01

392

Original Research Dynamics of Lateral Ventricle and Cerebrospinal  

E-print Network

, in turn, can be used to predict intracranial pressure (ICP) dynamics in normal and hydrocephalic brainsOriginal Research Dynamics of Lateral Ventricle and Cerebrospinal Fluid in Normal and Hydrocephalic (CSF) hydro- dynamics in normal subjects and hydrocephalic patients. Materials and Methods: Velocity

Linninger, Andreas A.

393

Sural--lateral plantar nerve communications in Japanese macaque.  

PubMed

It is generally accepted that the sural nerve in humans contains exclusively sensory and autonomic fibers. Recently, however, a few clinical reports have suggested that the human sural nerve contains motor fibers. On the other hand, it is known that motor fibers are present in the sural nerve of rats and dogs, and that the fibers reach intrinsic muscles of the foot via a communicating branch to the lateral plantar nerve. The author investigated the communicating branch between the sural and lateral plantar nerves in Japanese macaques, and examined both nerves by the fiber analysis method, removing the perineurium under a stereoscopic microscope. The communicating branch was found in all examined macaques. Nerve fibers which derived from the sural nerve via the branch reached the abductor digiti quinti, the flexor digiti quinti brevis, the contrahentes digitorum, the adductor hallucis, the interosseous and the lumbrical muscles. Furthermore, these fibers supplied the lateral part of the skin of the sole and the metatarsophalangeal joints. These findings in the Japanese macaques suggest that we may encounter the communicating branch between the sural and lateral plantar nerves in other primates including humans as in rats and dogs. PMID:10659577

Sekiya, S

1999-12-01

394

7. Historic American Buildings Survey Photocopy, August 1951 LATERAL VIEW, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. Historic American Buildings Survey Photocopy, August 1951 LATERAL VIEW, EAST FRONT, OLD PHOTOGRAPH c. 1850 Restricted: Permission for use must be obtained in writing from Art Library, Yale University, New Haven, Conn. - Skinner-Trowbridge House, 46 Hillhouse Avenue, New Haven, New Haven County, CT

395

Social Learning Modulates the Lateralization of Emotional Valence  

ERIC Educational Resources Information Center

Although neuropsychological studies of lateralization of emotion have emphasized valence (positive vs. negative) or type (basic vs. complex) dimensions, the interaction between the two dimensions has yet to be elucidated. The purpose of the current study was to test the hypothesis that recognition of basic emotions is processed preferentially by…

Shamay-Tsoory, Simone G.; Lavidor, Michal; Aharon-Peretz, Judith

2008-01-01

396

Transitions into and out of Cohabitation in Later Life  

ERIC Educational Resources Information Center

Cohabitation among adults over age 50 is rising rapidly, more than doubling from 1.2 million in 2000 to 2.75 million in 2010. A small literature provides a descriptive portrait of older cohabitors, but no study has investigated transitions into and out of cohabitation during later life. Drawing on demographic and life course perspectives, the…

Brown, Susan L.; Bulanda, Jennifer Roebuck; Lee, Gary R.

2012-01-01

397

The lateral stability of train suspension systems employing inerters  

Microsoft Academic Search

This paper investigates the benefits of lateral stability of train suspension systems employing a newly developed mechanical network element known as an inerter. An inerter was proposed as an ideal mechanical two-port element to substitute for the mass element in the mechanical\\/electrical analogy. As of now, inerters have been successfully applied to car and motorcycle suspension systems, for which significant

Fu-Cheng Wang; Min-Kai Liao

2010-01-01

398

Styling in a Language Learned Later in Life  

ERIC Educational Resources Information Center

This article analyses the styles of English produced by an adult migrant who started to speak the language later in life, and it approaches them from the perspective of quantitative style-shifting and discursive stylization. After defining style and the procedures needed to justify the term "L2," the study describes the focal…

Rampton, Ben

2013-01-01

399

The frizzled pathway regulates the development of arista laterals  

Microsoft Academic Search

BACKGROUND: The frizzled pathway in Drosophila has been studied intensively for its role in the development of planar polarity in wing hairs, thoracic bristles and ommatidia. Selected cells in the arista (the terminal segment of the antenna) elaborate a lateral projection that shares characteristics with both hairs and bristles. RESULTS: We found that mutations in putative downstream members of the

Biao He; Paul N Adler

2002-01-01

400

Amyotrophic Lateral Sclerosis: An Introduction to Psychosocial and Behavioral Adaptations.  

ERIC Educational Resources Information Center

Defines amyotrophic lateral sclerosis (ALS) as motor-neuron disease that is terminal. Discusses symptoms associated with ALS and identifies treatment options. Reviews psychological and behavioral adaptations in regard to ALS clients, their families, and professionals who work with them. Discusses support groups as method of reducing stress for ALS…

Hoffman, R. Leigh; Decker, Thomas W.

1993-01-01

401

Rasch Measurement in the Assessment of Amytrophic Lateral Sclerosis Patients.  

ERIC Educational Resources Information Center

Examined the sensitivity to change over time of the Amytrophic Lateral Sclerosis Assessment Questionnaire (ALSAQ-40; C. Jenkinson and others, 1999). Findings for 764 individuals show that the ALSAQ-40 is a valid and responsive disease-specific health-related quality of life instrument for studies of patients with motor neuron diseases. (SLD)

Norquist, Josephine M.; Fitzpatrick, Ray; Jenkinson, Crispin

2003-01-01

402

Neurotransmitter synthesis in inner ear and lateral line sense organs  

Microsoft Academic Search

HAIR cells of inner ear sense organs and of lateral line organs in fish are innervated by afferent nerve fibres, to which they transmit information about mechanical stimuli. Efferent inhibitory nerve fibres, which originate in the central nervous system, also innervate most hair cells at their base (Fig. 1b). Recent evidence indicates that both these synapses are chemical; excitatory postsynaptic

Åke Flock; DOMINIC M. K. LAM

1974-01-01

403

Lateral release of the patella: Indications and contraindications  

Microsoft Academic Search

Charts were reviewed on patients at the Salt Lake Knee and Sports Medicine Clinic who had had a lateral release of the patella. Patients were divided into two groups. Group I contained patients who were entirely satisfied with the procedure, and Group II included patients who were complete failures (defined as a need for further surgical procedures). In Group I,

Patricia A. Kolowich; Lonnie E. Paulos; Thomas D. Rosenberg; Steve Farnsworth

1990-01-01

404

Treatment for lateral epicondylitis: variables related to recovery  

Microsoft Academic Search

The purpose of this study was to determine the effectiveness of a treatment regime utilised for lateral epicondylitis that is designed to expedite return to activity and to identify variables related to treatment outcomes. Patients treated in a sports medicine clinic between 1978 and 1980 received, by mail, a brief questionnaire investigating the variables of the injuries and level of

S G Gerberich; J D Priest

1985-01-01

405

Acoustic Investigations into the Later Acquisition of Syllabic "-es" Plurals  

ERIC Educational Resources Information Center

Purpose: Children acquire /-ez/ syllabic plurals (e.g., buses) later than /-s, -z/ segmental plurals (e.g., cats,dogs). In this study, the authors explored whether increased syllable number or segmental factors best explains poorer performance with syllabic plurals. Method: An elicited imitation experiment was conducted with 14 two-year-olds…

Mealings, Kiri T.; Cox. Felicity; Demuth, Katherine

2013-01-01

406

Using Monomolecular Films to Characterize Lipid Lateral Interactions  

PubMed Central

Summary Membrane lipids are structurally diverse in ways that far exceed the role envisioned by Singer and Nicholson of simply providing a fluid bilayer matrix in which proteins reside. Current models of lipid organization in membranes postulate that lipid structural diversity enables nonrandom lipid mixing in each leaflet of the bilayer, resulting in regions with special physical and functional properties, i.e., microdomains. Central to understanding the tendencies of membrane lipids to mix nonrandomly in biomembranes is the identification and evaluation of structural features that control membrane lipid lateral mixing interactions in simple model membranes. The surface balance provides a means to evaluate the lateral interactions among different lipids at a most fundamental level—mixed in binary/ternary combinations that self-assemble at the air–water interface as monomolecular films, i.e., monolayers. Analysis of surface pressure and interfacial potential as a function of average cross-sectional molecular area provide insights into hydrocarbon chain ordering, lateral compressibility/elasticity, and dipole effects under various conditions including those that approximate one leaflet of a bilayer. Although elegantly simple in principle, effective use of the surface balance requires proper attention to various experimental parameters, which are described herein. Adequate attention to these experimental parameters ensures that meaningful insights are obtained into the lipid lateral interactions and enables lipid monolayers to serve as a basic platform for use with other investigative approaches. PMID:18214373

Brown, Rhoderick E.; Brockman, Howard L.

2008-01-01

407

Rotational synkineses of occiput and atlas on lateral inclination  

Microsoft Academic Search

An X-ray analysis was performed with regard to the question of synkinetic rotational movements of occiput and atlas on lateral inclination of the head and neck. It was found that the frequent synkinetic rotation of the head from the side of inclination can be taken for a stereotype that is ten times more frequent than the rotation towards the side

J. Jirout

1981-01-01

408

Pesticide detection using a lateral field excited acoustic wave sensor  

Microsoft Academic Search

Although organophosphate pesticides have been widely used in agriculture to control pests, they can have adverse effects on the environment and also enter the food chain causing adverse health effects in humans. Therefore, a need exists to develop a low-cost, robust, sensitive, and portable sensor for organophosphate pesticides. A lateral field excited (LFE) acoustic wave sensor has been developed in

Yihe Hu; Wade Pinkham; Lester A. French; David Frankel; John F. Vetelino

2005-01-01

409

Corn and Cotton Yield with Two Surface Drip Lateral Spacings  

Technology Transfer Automated Retrieval System (TEKTRAN)

Surface drip irrigation laterals were spaced next to crop rows (0.91 m) and in alternate row middles (1.83 m) to document crop yield and partial economic returns compared with non-irrigated areas. A surface drip irrigation system was installed at two sites on a Faceville (Site 1) and a Greenville (S...

410

Marijuana in the management of amyotrophic lateral sclerosis  

Microsoft Academic Search

Marijuana has been proposed as treatment for a widening spectrum of medical conditions. Marijuana is a substance with many properties that may be applicable to the management of amyotrophic lateral sclerosis (ALS). These include analgesia, muscle relaxation, bronchodilation, saliva reduction, appetite stimulation, and sleep induction. In addition, marijuana has now been shown to have strong antioxidative and neuroprotective effects, which

Gregory T. Carter; Bill S. Rosen

2001-01-01

411

LATERALIZATION OF KIN RECOGNITION SIGNALS IN THE HUMAN FACE  

E-print Network

LATERALIZATION OF KIN RECOGNITION SIGNALS IN THE HUMAN FACE MARIA F. DAL MARTELLO LAURENCE T Science New York University M. F. Dal Martello: Maria.DalMartello@unipd.it http, Journal of Vision, May 27, 2010 Corresponding author: Maria F. Dal Martello Department of General

Maloney, Laurence T.

412

Angiogenin variants in Parkinson disease and amyotrophic lateral sclerosis  

Microsoft Academic Search

OBJECTIVE: Several studies have suggested an increased frequency of variants in the gene encoding angiogenin (ANG) in patients with amyotrophic lateral sclerosis (ALS). Interestingly, a few ALS patients carrying ANG variants also showed signs of Parkinson disease (PD). Furthermore, relatives of ALS patients have an increased risk to develop PD, and the prevalence of concomitant motor neuron disease in PD

M. A. van Es; H. J. Schelhaas; P. W. van Vught; N. Ticozzi; P. M. Andersen; E. J. Groen; C. Schulte; H. M. Blauw; M. Koppers; F. P. Diekstra; K. Fumoto; A. L. Leclerc; P. Keagle; B. R. Bloem; H. Scheffer; B. F. L. van Nuenen; M. van Blitterswijk; W. van Rheenen; A. M. Wills; P. P. Lowe; G. F. Hu; W. Yu; H. Kishikawa; D. Wu; R. D. Folkerth; C. Mariani; S. Goldwurm; G. Pezzoli; P. van Damme; R. Lemmens; C. Dahlberg; A. Birve; R. Fernandez-Santiago; S. Waibel; C. Klein; M. Weber; A. J. van der Kooi; M. C. H. de Visser; D. Verbaan; J. J. van Hilten; P. Heutink; E. A. Hennekam; E. Cuppen; D. Van den Berg; R. H. Jr. Brown; V. Silani; T. Gasser; A. C. Ludolph; W. Robberecht; R. A. Ophoff; J. H. Veldink; R. J. Pasterkamp; P. I. de Bakker; J. E. Landers; B. P. C. van de Warrenburg; L. H. van den Berg

2011-01-01

413

Ethylene-Induced Lateral Expansion in Etiolated Pea Stems 1  

PubMed Central

Ethylene-induced inhibition of elongation and promotion of lateral expansion in the stems of etiolated pea (Pisum sativum L. var Alaska) seedlings is not associated with any alteration of auxin-stimulated proton extrusion. Indeed, lateral expansion in response to ethylene apparently requires an acidified wall since it is prevented by strong neutral buffers and by the ATPase inhibitor orthovanadate. Ethylene treatment reduces the capacity of live and frozen-thawed sections to extend in the longitudinal direction in response to acid. The effect of ethylene on lateral acid growth capacity is more complicated. Ethylene-treated internodes do not exhibit acid-induced lateral expansion. Ethylene-treated segments which have been frozen-thawed do show an enhanced capacity to extend in the transverse direction at acid pH, but only when the inner tissues have been removed by coring. We conclude that two of the factors which control the directionality of expansion during ethylene treatment are a decrease in the sensitivity of the walls to acid longitudinally and an increase in the sensitivity of the outer cortical parenchyma walls to acid in the transverse direction. PMID:16663230

Taiz, Lincoln; Rayle, David L.; Eisinger, William

1983-01-01

414

A Tutorial on Particle Filtering and Smoothing: Fifteen years later  

E-print Network

A Tutorial on Particle Filtering and Smoothing: Fifteen years later Arnaud Doucet The Institute. The objective of this tutorial is to provide a complete, up-to-date survey of this field as of 2008. Basic of particularly simple cases. The "particle" methods described by this tutorial are a broad and popular class

Del Moral , Pierre

415

A Tutorial on Particle Filtering and Smoothing: Fifteen years later  

E-print Network

A Tutorial on Particle Filtering and Smoothing: Fifteen years later Arnaud Doucet The Institute vision, econometrics, robotics and navigation. The objective of this tutorial is to provide a complete described by this tutorial are a broad and popular class of Monte Carlo algorithms which have been developed

Johansen, Adam

416

12. SOUTHWEST VIEW OF FIRST CENTRE FAMILY DWELLING HOUSE, LATER ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

12. SOUTHWEST VIEW OF FIRST CENTRE FAMILY DWELLING HOUSE, LATER FARMER DEACON'S SHOP, WITH SECOND CENTRE FAMILY DWELLING HOUSE IN BACKGROUND - Shaker Centre Family Dwelling House (First), North side of Village Road, North of U.S. Route 68 & State Route 33 intersection, Shakertown, Mercer County, KY

417

Mixed Lateral Dominance as a Predictive Factor of Learning Disability.  

ERIC Educational Resources Information Center

This report discusses the outcomes of a study of 147 children (ages 7-10) with learning disabilities that investigated the extent to which students legally classified with learning disabilities concurrently manifested mixed lateral dominance (MLD). The study was conducted to determine if MLD was a possible predictive factor for early…

Powers, P. J.; Putnam, Jon

418

Lateral Preference Patterns as a Discriminator of Learning Difficulties.  

ERIC Educational Resources Information Center

Compared lateral preference patterns for normal and learning-disabled children. Results indicated that learning-disabled children were more bilateral on factors involving visually fine motor activity, listening, and fine motor foot preference. Also studied the verbal-spatial abilities of learning-disabled children classified as normal or…

Dean, Raymond S.; And Others

1981-01-01

419

Lead Exposure as a Risk Factor for Amyotrophic Lateral Sclerosis  

Microsoft Academic Search

Background: The etiology of amyotrophic lateral sclerosis (ALS) likely involves an environmental component. We qualitatively assessed literature on ALS and lead exposure. Problems of study design make case reports and studies of lead in blood or tissues difficult to interpret. Most previous case-control studies found an association of ALS with self-reported occupational exposure to lead, with increased risks of 2-

F. Kamel; D. M. Umbach; H. Hu; T. L. Munsat; J. M. Shefner; J. A. Taylor; D. P. Sandler

2005-01-01

420

Diorhabda elongate and saltcedar control: 10 years later  

Technology Transfer Automated Retrieval System (TEKTRAN)

Saltcedar (Tamarix ramosissima), native to Central Asia, is a shrub or small tree that has invaded more than 1.9 million hectares of habitat in southwestern and western United States. Saltcedar was brought to the United States in the early 1800s as an ornamental and later planted for windbreaks and...

421

Lateral inhibition of Notch signaling in neoplastic cells  

PubMed Central

During normal development, heterogeneous expression of Notch ligands can result in pathway suppression in the signal-sending cell, a process known as lateral inhibition. It is unclear if an analogous phenomenon occurs in malignant cells. We observed significant induction of Notch ligands in glioblastoma neurospheres and pancreatic carcinoma cells cultured in low oxygen, suggesting that this phenomenon could occur around hypoxic regions. To model lateral inhibition in these tumors, the ligand Jagged1 was overexpressed in glioblastoma and pancreatic carcinoma cells, resulting in overall induction of pathway targets. However, when ligand high and ligand low cells from a single line were co-cultured and then separated, we noted suppression of Notch pathway targets in the former and induction in the latter, suggesting that neoplastic lateral inhibition can occur. We also found that repression of Notch pathway targets in signal-sending cells may occur through the activity of a Notch ligand intracellular domain, which translocates into the nucleus. Understanding how this neoplastic lateral inhibition process functions in cancer cells may be important in targeting ligand driven Notch signaling in solid tumors. PMID:25557173

Heth, Jason A.; Muraszko, Karin M.; Fan, Xing; Bar, Eli E.; Eberhart, Charles G.

2015-01-01

422

MICROBIOLOGY (for students entering Biology in Fall 2011 or later)  

E-print Network

MICROBIOLOGY (for students entering Biology in Fall 2011 or later) Graduation Requirements Requirement: Choose one of these four options: (Microbiology majors must choose BIOL 43800 and 43900, General Microbiology and Microbiology lab) A. BIOL 39500 Macromolecules (3 cr.; fall) B. BIOL 36600 Principles

Jiang, Wen

423

MICROBIOLOGY (for students entering Biology in Fall 2010 or later)  

E-print Network

MICROBIOLOGY (for students entering Biology in Fall 2010 or later) Graduation Requirements, Intro. To Evolution & Ecology (2 cr.; fall) 9. One of these four options: (Microbiology majors must choose BIOL 43800 and 43900, General Microbiology and Microbiology lab) A. BIOL 39500 Macromolecules (3

Jiang, Wen

424

Left Lateralized Enhancement of Orofacial Somatosensory Processing Due  

E-print Network

JSLHR Supplement Left Lateralized Enhancement of Orofacial Somatosensory Processing Due to Speech associated with speech articulatory movements affects the perception of speech sounds and vice versa, suggesting an intimate linkage between speech production and perception systems. However, it is unclear which

425

Severe hypoxia impairs lateralization in a marine teleost fish.  

PubMed

In intertidal environments, the recurring hypoxic condition at low tide is one of the main factors affecting fish behaviour, causing broad effects on ecological interactions. We assessed the effects of hypoxia on lateralization (e.g. the tendency to turn left or right), a behaviour related to brain functional asymmetry, which is thought to play a key role in several life history aspects of fish. Using staghorn sculpin (Leptocottus armatus), a benthic fish that typically inhabits the intertidal zone, we found that hypoxia affects behavioural lateralization at the population level. On average, staghorn sculpins showed a distinct preference for right turns under normoxic conditions (>90% oxygen saturation), but an equal probability of turning right or left after exposure to hypoxia for 2 h (20% oxygen saturation). The specific turning preference observed in the staghorn sculpin control population is likely to have an adaptive value, for example in predator-prey interactions by enhancing attack success or survival from predatory attacks. Therefore the alteration of lateralization expressed by staghorn sculpins under hypoxic conditions may have far-reaching implications for species ecology and trophic interactions. Moreover, our work raises the need to study this effect in other species, in which a hypoxia-driven disruption of lateralization could affect a wider range of behaviours, such as social interactions and schooling. PMID:25359933

Lucon-Xiccato, Tyrone; Nati, Julie J H; Blasco, Felipe Rocco; Johansen, Jacob L; Steffensen, John F; Domenici, Paolo

2014-12-01

426

Body tides of a convecting, laterally heterogeneous, and aspherical Earth  

E-print Network

Body tides of a convecting, laterally heterogeneous, and aspherical Earth Laurent Me´tivier1 November 2008. [1] Precise knowledge of Earth's body tides is crucial for correcting geodetic positioning, body tides are generally computed assuming a radially (or elliptically) stratified Earth. However

Conrad, Clint

427

Hot hole degradation effects in lateral nDMOS transistors  

Microsoft Academic Search

The degradation of a n-type lateral DMOS transistor is shown to be related to the injection of hot holes in the drift region field oxide. The saturation effects observed in the parameter shifts are reproduced by a new degradation model using the bulk current as the driving force. The dependency of the hot hole injection on the layout of the

P. Moens; G. Van den bosch; C. De Keukeleire; R. Degraeve; M. Tack; G. Groeseneken

2004-01-01

428

Laterality of breast cancer in the United States  

Microsoft Academic Search

Breast cancer laterality of over 250,000 cases from the Surveillance, Epidemiology, and End Results (SEER) program in the United States was studied in relation to gender, race, tumor stage, histology, age at diagnosis, year of diagnosis, estrogen receptor status, and marital status. The data, which include all invasive and in situ breast cancer cases in the SEER program during the

Helen A. Weiss; Susan S. Devesa; Louise A. Brinton

1996-01-01

429

Lateral sphenoid sinus recess cerebrospinal fluid leak: a case series.  

PubMed

The lateral recess of the sphenoid sinus is one of the most common sites of meningocele and spontaneous cerebrospinal fluid (CSF) leak. Despite the availability of several techniques for closure of skull base defects occurring in this location, recurrence still poses a major challenge. This report reviews the experience of surgical repair of lateral sphenoid sinus recess CSF leak at a tertiary referral center and provides a brief discussion of this rare lesion. Nine surgeries were performed for six cases of spontaneous lateral sphenoid sinus recess CSF leak (two revisions and one repair of a new defect). Two patients presented with intracranial hypertension (ICH) and four with meningocele or meningoencephalocele. The transpterygoid approach was used in two procedures. A multilayer graft was used in seven cases and a nasoseptal flap in two. Three patients received lumbar or ventricular shunts, and one received acetazolamide for ICH management. Two minor complications were recorded, and the overall surgical success rate was 78 %. We conclude that nasoseptal flaps are a valid option for repair of recurrent CSF leaks, particularly in the lateral sphenoid sinus recess. Furthermore, identification and correction of ICH plays an essential role in the success of treatment in this patient population. PMID:24748381

Melo, Nelson Almeida d'Ávila; Borges, Bruno Barros Pinto; Magliarelli Filho, Pedro Augusto; Godoy, Maria Dantas Costa Lima; Pereira, Larissa Vilela; Pinna, Fabio de Rezende; Voegels, Richard Louis

2014-09-01

430

Lateral Subcutaneous Internal Sphincterotomy in Treatment of Anal Fissure  

Microsoft Academic Search

One hundred and three patients with anal fissures have been treated by lateral internal sphincterotomy performed by a subcutaneous myotomy technique, and 99 have been successfully followed up for from 3 to 24 months (mean 11 months). The operation was free from significant complications, apart from slight reactionary bleeding in one case and a perianal abscess in another. The fissure

D. C. Hoffmann; J. C. Goligher

1970-01-01

431

A Lateral Transzygomatic-Transtemporal Approach to the Infratemporal Fossa  

PubMed Central

This report describes an alternative approach to the infratemporal fossa lesions through a lateral zygomato-temporal craniotemy, which modifies the extradural temporopolar technique for cavernous sinus surgery. First, an L-shaped osteotomy of the zygoma from the frontozygomatic suture attaching the zygomatre arch and low positioned temporal cramotomy are made. Through this zygomato-temporal craniotomy and orbitotemporal drilling, leaving the lateral orbital rim and orbital roof intact, skeletonization of the foramens rotundum and ovale are carried out. The key element of this infratemporal exposure is the dissection and mobilization of the trigeminal nerve, trigeminal second branch rostrally, and the third branch caudally, which facilitates a wide exposure of the infratemporal fossa with preserving trigeminal function. The corridor between the mobilized trigeminal branches provides direct access to the lateral and medial pterygoid plate, internal maxillary artery, sphenoid and maxillary sinuses, maxilla and, finally, the parapharyngeal area. Our experiences have demonstrated that this lateral transzygomatic-transtemporal exposure is satisfactory for use with infratemporal fossa tumors. This approach has an advantage for cranial-base exposure with decreased risks of cosmetic deformity and of trigeminal nerve dysfunction. ImagesFigure 2p279-bFigure 3Figure 4Figure 5Figure 6Figure 7Figure 8Figure 9p285-bFigure 10 PMID:17171117

Terasaka, Shunsuke; Sawamura, Yutaka; Goto, Shin; Fukushima, Takanori

1999-01-01

432

New investigation of short wings with lateral jets  

NASA Technical Reports Server (NTRS)

The lift of short wings by means of lateral fluid jets fired in the plane of the wing in the direction of the span is described. After some theoretical considerations, the experimental results obtained in a wind tunnel on a series of wings of various lengths are presented.

Carafoli, E.; Camarasescu, N.

1983-01-01

433

17. Photocopy of drawing, Erection Plan of Top Lateral Bracing ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

17. Photocopy of drawing, Erection Plan of Top Lateral Bracing of Bridge at South Norwalk for the N.Y., N.H. and H.R.R., dated June 12, 1895. Original on file with Metro North Commuter Railroad. - South Norwalk Railroad Bridge, South Main & Washington Streets, Norwalk, Fairfield County, CT

434

13. ONE OF TWO LATERAL ROOF TRUSSES AND ROOF SUPPORT ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

13. ONE OF TWO LATERAL ROOF TRUSSES AND ROOF SUPPORT BEAMS OF SARATOGA GAS LIGHT COMPANY GASHOLDER NO. 2 HOUSE LOOKING WEST. THE WIRES AND BEAM AT RIGHT CENTER OF PHOTOGRAPH HAVE BEEN ADDED TO STABILIZE TRUSS SYSTEM - Saratoga Gas Light Company, Gasholder No. 2, Niagara Mohawk Power Corporation Substation Facility, intersection of Excelsior & East Avenues, Saratoga Springs, Saratoga County, NY

435

Normal aging selectively diminishes alpha lateralization in visual spatial attention.  

PubMed

EEG studies of cue-induced visual alpha power (8-13 Hz) lateralization have been conducted on young adults without examining differences that may develop as a consequence of normal aging. Here, we examined age-related differences in spatial attention by comparing healthy older and younger adults. Our key finding is that cue-induced alpha power lateralization was observed in younger, but not older adults, even though both groups exhibited classic event-related potential signatures of spatial orienting. Specifically, both younger and older adults showed significant early directing-attention negativity (EDAN), anterior directing-attention negativity (ADAN), late directing-attention positivity (LDAP) and contingent negative variation (CNV). Furthermore, target-evoked sensory components were enhanced for attended relative to unattended targets in both younger and older groups. This pattern of results suggests that although older adults can successfully allocate spatial attention, they do so without the lateralization of alpha power that is commonly observed in younger adults. Taken together, our findings demonstrate that younger and older adults might engage different neural mechanisms for attentional orienting, and that alpha power lateralization during visual spatial attention is a phenomenon that diminishes during normal aging. PMID:25463457

Hong, Xiangfei; Sun, Junfeng; Bengson, Jesse J; Mangun, George R; Tong, Shanbao

2015-02-01

436

Female preference for male lateral projection area in Poecilia reticulata  

Microsoft Academic Search

The lateral projection area (LPA) hypothesis was investigated by presenting female guppies, Poecilia reticulata with a series of paired males in three experiments. One trait was held constant in each experiment (dorsal fin size in expt\\u000a I, body size in expt II, and total LPA in expt III) while body: dorsal fin ratio varied. Females spent more time near dummies

Ronald David MacLaren; Adam Fontaine

437

Headers will be added later Deriving groundwater estimates in Australia  

E-print Network

phenomenon. #12;Headers will be added later 2 Figure 1: The Earth's gravity field for the 10-day period. Tregoning 1 and S.C. McClusky 1 1 Research School of Earth Sciences, The Australian National University-resolution estimates of the constant and time-variable part of the Earth's gravity field with unprecedented accuracy

Tregoning, Paul

438

Surgery on the lateral nasal wall with the operation microscope.  

PubMed

Experiences with operations on the lateral nasal wall and the ethmoid with the operating microscope are reported. 18 suitable cases were operated on according to this technique. For the optimal distance optics with a focal distance of 250 mm are most suitable. Prerequisites for the operations are a self-supporting speculum and special instruments developed for this purpose. PMID:940973

Masing, H

1976-06-01

439

Paper No. : 0317 LATERAL SPREADING DURING CENTRIFUGE MODEL  

E-print Network

Paper No. : 0317 LATERAL SPREADING DURING CENTRIFUGE MODEL EARTHQUAKES Stuart K. Haigh1 , S sand marker lines within centrifuge models. A series of dynamic centrifuge model tests have been these free boundaries from previous earthquakes. Dynamic centrifuge modelling was carried out using sloping

Haigh, Stuart

440

Clostridium hastiforme is a later synonym of Tissierella praeacuta  

E-print Network

priority. An emended description of the genus Tissierella is also given. Clostridium hastiforme MacClostridium hastiforme is a later synonym of Tissierella praeacuta Jin-Woo Bae,1 Ja Ryeong Park,1 species Clostridium hastiforme and Tissierella praeacuta appear to be similar from their published

Bae, Jin-Woo

441

Lateral variability of overbank sedimentation on a Devon flood plain  

Microsoft Academic Search

Deployment of sediment traps over a 12-month period has enabled investigation of the lateral variability of overbank deposition rates and particle size composition of deposited sediment across a frequently inundated flood plain section of the River Culm, southeast Devon, UK. Although a general exponential decrease in deposition rate and grain size with distance from the channel occurs, significant deviations from

D. J. SIMM; D. E. WALLING

1999-01-01

442

Lateral variability of overbank sedimentation on a Devon flood plain  

Microsoft Academic Search

Deployment of sediment traps over a 12-month period has enabled investigation of the lateral variability of overbank deposition rates and particle size composition of deposited sediment across a frequently inundated flood plain section of the River Culm, southeast Devon, UK. Although a general exponential decrease in deposition rate and grain size with distance from the channel occurs, significant deviations from

D. J. SIMM; D. E. WALLING

1998-01-01

443

Lateral vibration: the key to BHA failure analysis  

SciTech Connect

Axial and torsional vibration analysis of three bottomhole assemblies was unable to identify the cause of repeated washouts and twistoffs. Finite element analysis, involving the six degrees of freedom available to the BHA and taking into account wellbore trajectory, WOB and other variables, established lateral vibrations as the probable culprit. Failures occurred when operating at speeds and in the drillstring locations predicted.

Mitchell, R.F.; Allen, M.B.

1985-03-01

444

Augmented Reality for Later Playback of Videos Project Proposal  

E-print Network

1 Augmented Reality for Later Playback of Videos Project Proposal Jordan Stratton Abstract: Augmented reality's popularity has recently exploded since mobile phones have had the capability a method of allowing the user to take a video and choose whether or not to have augmented reality on while

Miles, Will

445

Effects of later-occurring nonlinguistic sounds on speech categorization  

E-print Network

Effects of later-occurring nonlinguistic sounds on speech categorization Travis Wadea and Lori L values as instances of d when the sounds follow r as compared to l , effectively compen- sating 2005 Nonspeech stimuli influence phonetic categorization, but effects observed so far have been limited

Holt, Lori L.

446

9. VIEW SHOWING CHILDREN SWIMMING IN A LATERAL OF THE ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

9. VIEW SHOWING CHILDREN SWIMMING IN A LATERAL OF THE GRAND CANAL LOCATION UNKNOWN. THE HUGE COTTONWOOD TREES THAT ONCE-LINED MOST CANALS AND DITCHES WERE CUT DOWN WHEN IT WAS DISCOVERED THAT THEY CONSUMED HUNDREDS OF GALLONS OF WATER EACH DAY. Photographer unknown, no date - Grand Canal, North side of Salt River, Tempe, Maricopa County, AZ

447

BIOCHEMISTRY (for students entering Biology in Fall 2011 or later)  

E-print Network

1 BIOCHEMISTRY (for students entering Biology in Fall 2011 or later) Graduation Requirements Requirement: Choose one of these four options: (Biochemistry majors must choose BIOL 39500, Macromolecules) A Biochemistry (3 cr.; fall) 13. Biology Electives: Two of these courses: A. BIOL 41600 Viruses and Viral

Jiang, Wen

448

BIOCHEMISTRY (for students entering Biology in Fall 2010 or later)  

E-print Network

BIOCHEMISTRY (for students entering Biology in Fall 2010 or later) Graduation Requirements, Intro. To Evolution & Ecology (2 cr.; fall) 9. One of these four options: (Biochemistry majors must & Measurement in Physical Biochemistry (3 cr.; fall) 13. Two of these courses: A. BIOL 41600 Viruses and Viral

Jiang, Wen

449

Planning in Middle Childhood: Early Predictors and Later Outcomes  

ERIC Educational Resources Information Center

Data from 1,364 children and families who participated in the National Institute of Child Health and Human Development's Study of Early Child Care and Youth Development were analyzed to track the early correlates and later academic outcomes of planning during middle childhood. Maternal education, through its effect on parenting quality when…

Friedman, Sarah L.; Scholnick, Ellin K.; Bender, Randall H.; Vandergrift, Nathan; Spieker, Susan; Pasek, Kathy Hirsh; Keating, Daniel P.; Park, Yoonjung

2014-01-01

450

Lateral Symbiont Acquisition in a Maternally Transmitted Chemosynthetic Clam Endosymbiosis  

E-print Network

Lateral Symbiont Acquisition in a Maternally Transmitted Chemosynthetic Clam Endosymbiosis Frank J, Harvard University Deep-sea clams of the family Vesicomyidae live in symbiosis with intracellular-II clams from hydrothermal vents on the Juan de Fuca Ridge (northeastern Pacific) revealed a symbiont

Stewart, Frank

451

The Effect of Lateral Epicondylosis on Upper Limb Mechanical Parameters  

PubMed Central

Background Lateral epicondylosis is a prevalent and costly musculoskeletal disorder characterized by degeneration of the common extensor tendon origin at the lateral epicondyle. Grip strength is commonly affected due to lateral epicondylosis. However, less is known about the effect of lateral epicondylosis on other functional parameters such as ability to react to rapid loading. Methods Twenty-nine lateral epicondylosis participants and ten controls participated in a case-control study comparing mechanical parameters (mass, stiffness and damping), magnetic resonance imaging signal intensity and grip strength of injured and uninjured limbs. A mixed effects model was used to assess the effect of dominance and injury on mechanical parameters and grip strength. Findings Significant effect of injury and dominance was observed on stiffness, damping and grip strength. An injured upper limb had, on average, 18% less stiffness (p<0.01, 95% CI [9.8%, 26%]), 21% less damping (p<0.01, 95% CI [11%, 31%]) and 50% less grip strength (p<0.01, 95% CI [37%, 61%]) than an uninjured upper limb. The dominant limb had on average 15% more stiffness (p<0.01, 95% CI [8.0%, 23%], 33% more damping (p<0.01, 95% CI [22%, 45%]), and 24% more grip strength (p<0.01, 95% CI [6.6%, 44%]) than the non-dominant limb. Interpretation Lower mechanical parameters are indicative of a lower capacity to oppose rapidly rising forces and quantify an important aspect of upper limb function. For individuals engaged in manual or repetitive activities involving the upper limb, a reduction in ability to oppose these forces may result in increased risk for injury or recurrence. PMID:21937156

Chourasia, Amrish O.; Buhr, Kevin A.; Rabago, David P.; Kijowski, Richard

2011-01-01

452

One-dimensional breakdown voltage model of SOI RESURF lateral power device based on lateral linearly graded approximation  

NASA Astrophysics Data System (ADS)

A novel one-dimensional (1D) analytical model is proposed for quantifying the breakdown voltage of a reduced surface field (RESURF) lateral power device fabricated on silicon on an insulator (SOI) substrate. We assume that the charges in the depletion region contribute to the lateral PN junctions along the diagonal of the area shared by the lateral and vertical depletion regions. Based on the assumption, the lateral PN junction behaves as a linearly graded junction, thus resulting in a reduced surface electric field and high breakdown voltage. Using the proposed model, the breakdown voltage as a function of device parameters is investigated and compared with the numerical simulation by the TCAD tools. The analytical results are shown to be in fair agreement with the numerical results. Finally, a new RESURF criterion is derived which offers a useful scheme to optimize the structure parameters. This simple 1D model provides a clear physical insight into the RESURF effect and a new explanation on the improvement in breakdown voltage in an SOI RESURF device. Project supported by the National Natural Science Foundation of China (Grant No. 61076073) and the Specialized Research Fund for the Doctoral Program of Higher Education of China (Grant No. 20133223110003).

Zhang, Jun; Guo, Yu-Feng; Xu, Yue; Lin, Hong; Yang, Hui; Hong, Yang; Yao, Jia-Fei

2015-02-01

453

Start Later, Sleep Later: School Start Times and Adolescent Sleep in Homeschool Versus Public/Private School Students.  

PubMed

Homeschooled students provide a naturalistic comparison group for later/flexible school start times. This study compared sleep patterns and sleep hygiene for homeschooled students and public/private school students (grades 6-12). Public/private school students (n = 245) and homeschooled students (n = 162) completed a survey about sleep patterns and sleep hygiene. Significant school group differences were found for weekday bedtime, wake time, and total sleep time, with homeschooled students waking later and obtaining more sleep. Homeschooled students had later school start times, waking at the same time that public/private school students were starting school. Public/private school students had poorer sleep hygiene practices, reporting more homework and use of technology in the hour before bed. Regardless of school type, technology in the bedroom was associated with shorter sleep duration. Later school start times may be a potential countermeasure for insufficient sleep in adolescents. Future studies should further examine the relationship between school start times and daytime outcomes, including academic performance, mood, and health. PMID:25315902

Meltzer, Lisa J; Shaheed, Keisha; Ambler, Devon

2014-10-14

454

Vehicle state estimation for advanced vehicle motion control using novel lateral tire force sensors  

Microsoft Academic Search

In this paper, new real-time methods for the lateral vehicle velocity and roll angle estimation are presented. Lateral tire forces, obtained from a multi-sensing hub (MSHub) unit, are used to estimate lateral vehicle velocity and a roll angle. In order to estimate lateral vehicle velocity, the recursive least square (RLS) algorithm is utilized based on a linear vehicle model and

Kanghyun Nam; Sehoon Oh; Hiroshi Fujimoto; Yoichi Hori

2011-01-01

455

Soft Tissue Restraints to Lateral Patellar Translation in the Human Knee  

Microsoft Academic Search

The purpose of this investigation was to identify and quantify the soft tissue restraints, both medially and laterally, to lateral patellar translation. These restraints to lateral patellar translation at 20° of knee flexion were tested biomechanically on a universal testing instrument in nine fresh-frozen cadaveric knees. After preconditioning the tissues, the patella of each intact knee was translated laterally to

Stephen M. Desio; Robert T. Burks; Kent N. Bachus

1998-01-01

456

Ascending and descending mechanisms of visual lateralization in pigeons  

PubMed Central

Brain asymmetries are a widespread phenomenon among vertebrates and show a common behavioural pattern. The right hemisphere mediates more emotional and instinctive reactions, while the left hemisphere deals with elaborated experience-based behaviours. In order to achieve a lateralized behaviour, each hemisphere needs different information and therefore different representations of the world. However, how these representations are accomplished within the brain is still unknown. Based on the pigeon's visual system, we present experimental evidence that lateralized behaviour is the result of the interaction between the subtelencephalic ascending input directing more bilateral visual information towards the left hemisphere and the asymmetrically organized descending telencephalic influence on the tecto-tectal balance. Both the bilateral representation and the forebrain-modulated information processing might explain the left hemispheric dominance for complex learning and discrimination tasks. PMID:19064354

Valencia-Alfonso, Carlos-Eduardo; Verhaal, Josine; Güntürkün, Onur

2008-01-01

457

Lateral optical force on chiral particles near a surface  

PubMed Central

Light can exert radiation pressure on any object it encounters and that resulting optical force can be used to manipulate particles. It is commonly assumed that light should move a particle forward and indeed an incident plane wave with a photon momentum ?k can only push any particle, independent of its properties, in the direction of k. Here we demonstrate, using full-wave simulations, that an anomalous lateral force can be induced in a direction perpendicular to that of the incident photon momentum if a chiral particle is placed above a substrate that does not break any left–right symmetry. Analytical theory shows that the lateral force emerges from the coupling between structural chirality (the handedness of the chiral particle) and the light reflected from the substrate surface. Such coupling induces a sideway force that pushes chiral particles with opposite handedness in opposite directions. PMID:24598792

Wang, S. B.; Chan, C. T.

2014-01-01

458

Lateral Ankle Sprain and Chronic Ankle Instability: A Critical Review.  

PubMed

Many studies investigated the contributing factors of chronic ankle instability, but a consensus has not yet been obtained. The objective of this critical review is to provide recent scientific evidence on chronic ankle instability, including the epidemiology and pathology of lateral ankle sprain as well as the causative factors of chronic ankle instability. We searched MEDLINE from 1964 to December 2013 using the terms ankle, sprain, ligament, injury, chronic, functional, mechanical, and instability. Lateral ankle sprain shows a very high recurrence rate and causes considerable economic loss due to medical care, prevention, and secondary disability. During the acute phase, patients with ankle sprain demonstrate symptoms such as pain, range of motion deficit, postural control deficit, and muscle weakness, and these symptoms may persist, leading to chronic ankle instability. Although some agreement regarding the effects of chronic ankle instability with deficits in postural control and/or concentric eversion strength exists, the cause of chronic ankle instability remains controversial. PMID:24962695

Kobayashi, Takumi; Gamada, Kazuyoshi

2014-06-24

459

A Lateral Tensile Fracturing Model for Listric Fault  

NASA Astrophysics Data System (ADS)

The new discovery of a major seismic fault of the great 1976 Tangshan earthquake suggests a lateral tensile fracturing process at the seismic source. The fault is in listric shape but can not be explained with the prevailing model of listric fault. A double-couple of forces without moment is demonstrated to be applicable to simulate the source mechanism. Based on fracture mechanics, laboratory experiments as well as numerical simulations, the model is against the assumption of stick-slip on existing fault as the cause of the earthquake but not in conflict with seismological observations. Global statistics of CMT solutions of great earthquakes raises significant support to the idea that lateral tensile fracturing might account for not only the Tangshan earthquake but also others.

Qiu, Z.

2007-12-01

460

Familial aggregation of maxillary lateral incisor agenesis (MLIA)  

PubMed Central

Agenesis of maxillary lateral incisors and mandibular second premolars is the most frequent form of hypodontia. Its prevalence varies across population from 0.8% to 4.5%. Genetic aberrations and environmental factors may cause agenesis of one or more teeth. The management of child having such a problem is very important since diastema in teeth especially in upper anteriors not only affects child's physical appearance but also its psychological development as the child wants to look like other children. In this article is presented a case of non-syndromic agenesis of maxillary lateral incisors (MLIA) and mandibular central incisors in a 10-year-old boy (patient) in permanent dentition with its management along with the radiographic investigations and photographic presentations of the other members of his family affected with this condition. PMID:23536620

Pandey, Pallavi; Ansari, Afroz Alam; Choudhary, Kartik; Saxena, Aditya

2013-01-01

461

Lateralization of spatial relation processing in natural scenes.  

PubMed

Spatial relations between objects can be represented in a categorical and in a coordinate manner. Categorical representations reflect abstract relations, like 'left of' or 'under', whereas coordinate representations concern exact metric distances between objects. These two types of spatial relations are thought to be linked to a left hemisphere and a right hemisphere advantage, respectively. This lateralization pattern was examined in a visual search task, making use of natural scenes, in patients with unilateral brain damage and healthy controls. In addition, all participants performed a low-level spatial relation processing task. The results suggest that the lateralization pattern commonly found for spatial relation processing in low-level perceptual tasks is also applicable to the processing of complex visual scenes. PMID:22713416

van der Ham, Ineke J M; van Zandvoort, Martine J E; Postma, Albert

2013-01-01

462

Duodenal exclusion for management of lateral duodenal fistulas.  

PubMed

The first clinical application of pyloric occlusion with gastrojejunostomy (duodenal exclusion) for management of lateral duodenal fistulas was reported by Berg in 1907. More recently Berne et al. applied this procedure to treat patients with complex pancreaticoduodenal trauma and modified it to include antrectomy with Billroth II reconstruction and tube duodenostomy. Over time the indications for duodenal exclusion have gradually been expanded to include management of actual or anticipated duodenal fistulas arising from operative injury or as a complication of inflammatory or neoplastic diseases. Our recent success using duodenal exclusion and/or diverticularization to manage one patient with duodenal trauma and two patients with nontraumatic forms of duodenal injury resulting in lateral duodenal fistulas caused us to reevaluate the efficacy of this procedure and forms the basis for this report. PMID:3348552

Eckhauser, F E; Strodel, W E; Knol, J A; Guice, K S

1988-03-01

463

Lateral Habenula determines long-term storage of aversive memories  

PubMed Central

The Lateral Habenula (LHb) is a small brain structure that codifies negative motivational value and has been related to major depression. It has been shown recently that LHb activation is sufficient to induce aversive associative learning; however the key question about whether LHb activation is required for an aversive memory to be formed has not been addressed. In this article we studied the function of the LHb in memory formation using the Inhibitory Avoidance task (IA). We found that LHb inactivation during IA training does not disrupt memory when assessed 24 h after, but abolishes it 7 days later, indicating that LHb activity during memory acquisition is not necessary for memory formation, but regulates its temporal stability. These effects suggest that LHb inactivation modifies subjective perception of the training experience. PMID:24860453

Tomaiuolo, Micol; Gonzalez, Carolina; Medina, Jorge H.; Piriz, Joaquin

2014-01-01

464

Lateral Habenula determines long-term storage of aversive memories.  

PubMed

The Lateral Habenula (LHb) is a small brain structure that codifies negative motivational value and has been related to major depression. It has been shown recently that LHb activation is sufficient to induce aversive associative learning; however the key question about whether LHb activation is required for an aversive memory to be formed has not been addressed. In this article we studied the function of the LHb in memory formation using the Inhibitory Avoidance task (IA). We found that LHb inactivation during IA training does not disrupt memory when assessed 24 h after, but abolishes it 7 days later, indicating that LHb activity during memory acquisition is not necessary for memory formation, but regulates its temporal stability. These effects suggest that LHb inactivation modifies subjective perception of the training experience. PMID:24860453

Tomaiuolo, Micol; Gonzalez, Carolina; Medina, Jorge H; Piriz, Joaquin

2014-01-01

465

Delivering the Lateral Inhibition Punchline: It's All About the Timing  

NSDL National Science Digital Library

Experimental and theoretical biologists have long been fascinated with the emergence of self-organizing patterns in developing organisms, and much attention has focused on Notch-mediated lateral inhibition. Within sheets of cells that may adopt either of two possible cell fates, lateral inhibition establishes patterns through the activity of a negative intercellular feedback loop involving the receptor, Notch, and its ligands Delta or Serrate. Despite a long history of intensive study in Drosophila, where the mechanism was first described, as well as in other organisms, new work continues to yield important insights. Mathematical modeling, combined with biological analyses, has now shed light on two features of the process: how antagonistic and activating ligand-receptor interactions work together to accelerate inhibition and ensure fidelity, and how filopodial dynamics contribute to the observed pattern refinement and spacing.

Jeffrey D. Axelrod (Stanford University School of Medicine; Department of Pathology REV)

2010-10-26

466

Origin of Lateral Nanoscale Heterogeneities in Weak Polyelectrolyte Brushes  

NASA Astrophysics Data System (ADS)

In this talk, we will first discuss experimental evidence of lateral nanoscale heterogeneities in a single-component weak polyelectrolyte brush system under zero to low salt conditions. Using an amphiphilic diblock copolymer, poly(2-(dimethylamino)ethyl methacrylate-b-n-butyl acrylate) (PDMAEMA-PnBA), for Langmuir film compression and Langmuir-Blodgett deposition on a hydrophobic substrate followed by fluid AFM imaging, we show the existence of regions of different brush heights, indicative of the thermodynamic instability (and resultant local clustering) of the PDMAEMA chains in the low-salt limit. Using SCF and scaling theories, we will also show that the lateral heterogeneities occur due to the combined effects of (i) the osmotic instability regulated by charge equilibrium and (ii) the hydrophobicity of the chains.

Won, You-Yeon; Witte, Kevin; Hur, Jaehyun

2009-03-01

467

A Rare Occurrence of Geminated-Taloned Maxillary Lateral Incisor  

PubMed Central

ABSTRACT The talon cusp is a developmental anomaly characterized by the presence of an accessory cusp like structure projecting from the cingulum area of the anterior teeth. Gemination is an anomaly caused by a single tooth germ that attempted to divide during its development. These developmental anomalies may cause clinical problems including esthetic impairment, pain, caries and tooth crowding. Co-occurrence of two anomalies in a teeth is rare. This paper presents an unusual case of talon cusp on geminated permanent lateral incisor. How to cite this article: Neeraja R, Kayal VG. A Rare Occurrence of Geminated-Taloned Maxillary Lateral Incisor. Int J Clin Pediatr Dent 2012;5(2):136-138. PMID:25206153

Kayal, Vizhi G

2012-01-01

468

A rare occurrence of geminated-taloned maxillary lateral incisor.  

PubMed

The talon cusp is a developmental anomaly characterized by the presence of an accessory cusp like structure projecting from the cingulum area of the anterior teeth. Gemination is an anomaly caused by a single tooth germ that attempted to divide during its development. These developmental anomalies may cause clinical problems including esthetic impairment, pain, caries and tooth crowding. Co-occurrence of two anomalies in a teeth is rare. This paper presents an unusual case of talon cusp on geminated permanent lateral incisor. How to cite this article: Neeraja R, Kayal VG. A Rare Occurrence of Geminated-Taloned Maxillary Lateral Incisor. Int J Clin Pediatr Dent 2012;5(2):136-138. PMID:25206153

Neeraja, R; Kayal, Vizhi G

2012-05-01

469

Trace element evidence for a laterally inhomogeneous moon  

NASA Technical Reports Server (NTRS)

A number of trace element interrelationships support the concept of a laterally inhomogeneous moon based originally on Clr/P2O5 ratios. The correspondence between Clr/P2O3 and Rb/Sr ratios in basalts are of special interest since the isotropic evolution of the latter pair of elements relates to the earliest history of the moon. This implies the times when the Clr/P2O5 relationships were established. The early magma ocean is conjectured to have been made up of non-intermixing seas resulting either from large convection cells or large body accretion. These mutually exclusive regions could be lunar geological provinces. It is proposed that the diversity of basalts from the Apollo 17 site is related to the lateral inhomogeneity of the moon. Ca/Na ratios in basalts show a trend which parallels that of Ru/Os and in a corresponding fashion may serve as a depth indicator.

Jovanovic, S.; Reed, G. W., Jr.

1978-01-01

470

Amyotrophic lateral sclerosis: new genes, new models, and new mechanisms  

PubMed Central

Research aimed at understanding amyotrophic lateral sclerosis (ALS) has seen exceptional growth in the past few years. New genes, new models, and new mechanisms have not only improved our understanding, but also contributed to the increasing complexity of ALS pathogenesis. The focus of this piece is to highlight some of the more notable developments in the field and to encourage a re-appreciation for the superoxide dismutase 1 (SOD1) mouse models. PMID:21941597

Dion, Patrick A.; Rouleau, Guy A.

2011-01-01

471

Detection of lateral composition modulation by magnetoexciton spectroscopy  

SciTech Connect

An experimental signature for detecting spontaneous lateral composition modulation in a (InAs){sub n}/(GaAs){sub m} short period superlattice on an InP substrate based on magnetoexciton spectroscopy described. The authors find by aligning the magnetic field in three crystallographic directions, one parallel to and the other two perpendicular to the composition modulation direction, that the magnetoexciton shifts are anisotropic and are a good indicator for the presence of composition modulation.

Jones, E.D.; Millunchick, J.M.; Follstaedt, D.; Lee, S.; Reno, J.; Twesten, R.D. [Sandia National Labs., Albuquerque, NM (United States); Zhang, Y.; Mascerenhas, A. [National Renewable Energy Lab., Golden, CO (United States)

1997-07-10

472

Cornering stiffness estimation based on vehicle lateral dynamics  

Microsoft Academic Search

In this article, the cornering stiffness estimation problem based on the vehicle bicycle (one-track) model is studied. Both time-domain and frequency-domain-based methods are analyzed, aiming to estimate the effective cornering stiffness, defined as the ratio between the lateral force and the slip angle at the two axles. Several methods based on the bicycle model were developed, each having specific pros\\/cons

C. Sierra; E. Tseng; A. Jain; H. Peng

2006-01-01

473

Lateral migration of linear dunes in the Strzelecki Desert, Australia  

USGS Publications Warehouse

Preferential accumulation of sand on east-facing flanks indicates that the dunes migrated eastward several metres during the Holocene. Moreover, the west-facing flanks of some dunes have experienced a minimum of tens of metres of erosion. This asymmetric erosion and deposition were caused by dune obliquity and lateral migration that may have begun as early as the Pleistocene. Dunes in the Strzelecki Desert and in the adjacent Simpson Desert display a variety of grossly different internal structures. -from Author

Rubin, D.M.

1990-01-01

474

[Lateral transmandibular route for deep-lobe parotid tumor excision].  

PubMed

The parapharyngeal space may be a site for tumors, especially for those developed in the deep parotid lobe. The surgical route to parapharyngeal space tumors is a challenge because of neighbor anatomic structures and the specific risk of mandibular nerve damage. The aim of this study was to describe an original lateral transmandibular route, setting aside the mandible angle and preserving the mandibular nerve. PMID:19423144

Savoldelli, C; Righini, C; Reyt, E; Lebeau, J; Bettega, G

2009-06-01

475

ER Stress and Unfolded Protein Response in Amyotrophic Lateral Sclerosis  

Microsoft Academic Search

Several theories on the pathomechanism of amyotrophic lateral sclerosis (ALS) have been proposed: misfolded protein aggregates,\\u000a mitochondrial dysfunction, increased glutamate toxicity, increased oxidative stress, disturbance of intracellular trafficking,\\u000a and so on. In parallel, a number of drugs that have been developed to alleviate the putative key pathomechanism of ALS have\\u000a been under clinical trials. Unfortunately, however, almost all studies have

Kohsuke Kanekura; Hiroaki Suzuki; Sadakazu Aiso; Masaaki Matsuoka

2009-01-01

476

The Far Lateral Approach to Lumbar Disc Herniations  

Microsoft Academic Search

\\u000a The diagnosis of extreme lateral lumbar disc herniation (ELLDH) as a cause of lumbar radiculopathy was first described by\\u000a Abdullah in 1974 [1]. This discal pathology has been recognized for many years as an occasional cause of negative disc exploration and immediate\\u000a failure of classical disc surgery in sciatica [1,18, 24, 25, 29, 31, 30, 31, 33, 35, 41]. Only

F. Porchet; H. Fankhauser; N. DE TRIBOLET

477

Connexin26-mediated transfer of laterality cues in Xenopus  

PubMed Central

Summary A cilia-driven leftward flow of extracellular fluid breaks bilateral symmetry in the dorsal midline of the neurula stage vertebrate embryo. The left-specific Nodal signaling cascade in the lateral plate mesoderm (LPM) is key to asymmetric morphogenesis and placement of organs during subsequent development. The nature of the initial asymmetric cue(s) as well as the transfer of information from the midline to the left side has remained elusive. Gap junctional communication has been previously involved in Xenopus left-right (LR) development, however a function at cleavage stages was inferred from inhibitor experiments. Here we show by heptanol-mediated block of connexin function that flow stages during neurulation represent the critical time window. Flow in Xenopus occurs at the gastrocoel roof plate (GRP), a ciliated sheath of cells of mesodermal fate transiently positioned within the dorsal epithelial lining of the forming archenteron. We reasoned that endodermal cells immediately adjacent to the GRP are important for transfer of asymmetry. A systematic screen identified two connexin genes, Cx26 and Cx32, which were co-expressed in these lateral endodermal cells. Gain- and loss-of-function experiments pinpointed Cx26 as the critical connexin for LR development, while Cx32 had no effect on laterality. Importantly, GRP morphology, ciliation and flow were not affected in Cx26 morphants. Our results demonstrate a decisive role of Cx26 in the transfer of laterality cues from the GRP to the left LPM, providing a novel access to the identification of the initial asymmetric signal generated by flow. PMID:23213439

Beyer, Tina; Thumberger, Thomas; Schweickert, Axel; Blum, Martin

2012-01-01

478

Connexin26-mediated transfer of laterality cues in Xenopus.  

PubMed

A cilia-driven leftward flow of extracellular fluid breaks bilateral symmetry in the dorsal midline of the neurula stage vertebrate embryo. The left-specific Nodal signaling cascade in the lateral plate mesoderm (LPM) is key to asymmetric morphogenesis and placement of organs during subsequent development. The nature of the initial asymmetric cue(s) as well as the transfer of information from the midline to the left side has remained elusive. Gap junctional communication has been previously involved in Xenopus left-right (LR) development, however a function at cleavage stages was inferred from inhibitor experiments. Here we show by heptanol-mediated block of connexin function that flow stages during neurulation represent the critical time window. Flow in Xenopus occurs at the gastrocoel roof plate (GRP), a ciliated sheath of cells of mesodermal fate transiently positioned within the dorsal epithelial lining of the forming archenteron. We reasoned that endodermal cells immediately adjacent to the GRP are important for transfer of asymmetry. A systematic screen identified two connexin genes, Cx26 and Cx32, which were co-expressed in these lateral endodermal cells. Gain- and loss-of-function experiments pinpointed Cx26 as the critical connexin for LR development, while Cx32 had no effect on laterality. Importantly, GRP morphology, ciliation and flow were not affected in Cx26 morphants. Our results demonstrate a decisive role of Cx26 in the transfer of laterality cues from the GRP to the left LPM, providing a novel access to the identification of the initial asymmetric signal generated by flow. PMID:23213439

Beyer, Tina; Thumberger, Thomas; Schweickert, Axel; Blum, Martin

2012-05-15

479

Lateral ankle ligament anesthesia significantly alters single limb postural control.  

PubMed

Lateral ankle anesthesia has been used as a model to explore effects of ligament deafferentation related to ankle sprain on single limb postural control with conflicting results. Time-to-boundary (TTB) is a postural control measurement technique found to be sensitive in detecting subtle deficits in postural control in those with chronic ankle instability. The objective of this study was to determine the effects of lateral ankle ligament anesthesia on TTB measures of single limb postural control in healthy adults. Twenty-two healthy adults with no history of lower extremity injury within the past 6 months or balance disorders participated in the study. All subjects received a lidocaine injection to the lateral ankle structures on one of two testing days. On both testing days, subjects performed 3 eyes open and 3 eyes closed, 10-s trials of barefoot single limb stance on a forceplate. The dependent variables were the mean of TTB minima(s) and standard deviation of TTB minima(s) in mediolateral (ML) and anteroposterior (AP) directions. Separate condition (anesthesia, control) by vision (eyes open, eyes closed) ANOVAs with repeated measures were used for each TTB variable to determine the effects of anesthesia on postural control. Alpha level was set a priori at p?0.05. The anesthesia day TTBAP magnitude (p=0.008) and variability (p=0.044) measures were significantly lower than the control day, regardless of vision. Anesthesia of the lateral ankle ligamentous structures significantly reduced the magnitude and variability of TTBAP measures. These findings are similar to deficits found in those with chronic ankle instability. PMID:20663671

McKeon, P O; Booi, M J; Branam, B; Johnson, D L; Mattacola, C G

2010-07-01

480

Study of flow induced by nonuniform lateral injection  

Microsoft Academic Search

The cold flowfield in a closed-end 90 m-porosity porous-walled two-dimensional duct at the nonuniform lateral injection condition (approximately exponential distribution) has been investigated, using both laser-Doppler velocimetry measurements and theoretical analysis. The measured and predicted similar velocity profiles are in reasonable agreement, and the conditions for the existence of similarity are identified. A comparison with the previous case of uniform

T.-M. Liou; M.-K. Tsai

1991-01-01

481

Congenital lateral upper lip sinus: a rare case.  

PubMed

Congenital lateral sinuses of upper lip are malformations with uncertain etiology. These blind sinuses through orbicularis oris muscle have no intra-oral communication, with surgical excision being treatment of choice. We present our case referred to us as a patient of posttraumatic salivary fistula. Surgical management and possible etiology is discussed briefly. Also highlighted is the importance good history taking and meticulous clinical examination to accurately diagnose the entity in order to avoid expensive supportive radiological investigations. PMID:23904732

Bhatnagar, Ankur; Musa, Osman; Gildiyal, J P; Pandey, Mahesh

2012-08-01

482

The mapping of visual space by dragonfly lateral ocelli  

Microsoft Academic Search

We study the extent to which the lateral ocelli of dragonflies are able to resolve and map spatial information, following\\u000a the recent finding that the median ocellus is adapted for spatial resolution around the horizon. Physiological optics are\\u000a investigated by the hanging-drop technique and related to morphology as determined by sectioning and three-dimensional reconstruction.\\u000a L-neuron morphology and physiology are investigated

Richard Berry; Joshua van Kleef; Gert Stange

2007-01-01

483

Multi-directional sorting modes in deterministic lateral displacement devices  

E-print Network

Deterministic lateral displacement (DLD) devices separate micrometer-scale particles in solution based on their size using a laminar microfluidic flow in an array of obstacles. We investigate array geometries with rational row-shift fractions in DLD devices by use of a simple model including both advection and diffusion. Our model predicts novel multi-directional sorting modes that could be experimentally tested in high-throughput DLD devices containing obstacles that are much smaller than the separation between obstacles.

Long, Brian R; Beech, Jason P; Linke, Heiner; Bruus, Henrik; Tegenfeldt, Jonas O

2008-01-01

484

The lateral facies of ignimbrites at Laacher See volcano  

Microsoft Academic Search

Valley-fill ignimbrites of the Middle Laacher See Tephra (MLST) in the proximal depositional fan south of Laacher See volcano are laterally continuous with fine-grained overbank-facies deposits, 0.5–1.5 m thick, covering higher elevations and interfluves between the paleovalleys. The overbank deposits consist of up to 12 ash layers, each 4–10 cm thick, which show internal structures typical of ash-flow transport, such

Rolf Schumacher; Hans-Ulrich Schmincke

1990-01-01

485

The Lateral Decubitus Breast Boost: Description, Rationale, and Efficacy  

SciTech Connect

Purpose: To describe and evaluate the modified lateral decubitus boost, a breast irradiation technique. Patients are repositioned and resimulated for electron boost to minimize the necessary depth for the electron beam and optimize target volume coverage. Methods and Materials: A total of 2,606 patients were treated with post-lumpectomy radiation at our institution between January 1, 2000, and February 1, 2008. Of these, 231 patients underwent resimulation in the lateral decubitus position with electron boost. Distance from skin to the maximal depth of target volume was measured in both the original and boost plans. Age, body mass index (BMI), boost electron energy, and skin reaction were evaluated. Results: Resimulation in the lateral decubitus position reduced the distance from skin to maximal target volume depth in all patients. Average depth reduction by repositioning was 2.12 cm, allowing for an average electron energy reduction of approximately 7 MeV. Mean skin entrance dose was reduced from about 90% to about 85% (p < 0.001). Only 14 patients (6%) experienced moist desquamation in the boost field at the end of treatment. Average BMI of these patients was 30.4 (range, 17.8-50.7). BMI greater than 30 was associated with more depth reduction by repositioning and increased risk of moist desquamation. Conclusions: The lateral decubitus position allows for a decrease in the distance from the skin to the target volume depth, improving electron coverage of the tumor bed while reducing skin entrance dose. This is a well-tolerated regimen for a patient population with a high BMI or deep tumor location.

Ludwig, Michelle S., E-mail: mludwig@mdanderson.or [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX (United States); McNeese, Marsha D.; Buchholz, Thomas A.; Perkins, George H.; Strom, Eric A. [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX (United States)

2010-01-15

486

Unprecedented directed lateral lithiations of tertiary carbons on NHC platforms.  

PubMed

Unexpected and unprecedented directed remote lateral lithiation at one CH(CH3)2 of the 3-(2,6-di-isopropylphenyl) wingtip took place upon the reaction of functionalised N-heterocyclic carbene-type molecules with excess of LiCH2SiMe3, leading to dilithiated dianionic 4-amido-N-heterocyclic carbenes. DFT calculations show that the nature of the isolated species are under thermodynamic control. PMID:25412497

Danopoulos, Andreas A; Braunstein, Pierre; Rezabal, Elixabete; Frison, Gilles

2015-02-21

487

The tanycytic ependymoma of the lateral ventricle: case report.  

PubMed

The tanycytic ependymoma is an extremely rare, primitive neuroectodermal tumor, arising from the ependymoglial cells or tanycytes. Such cells are generally seen in the primitive nervous system instead of the mature ependymal cells. The tanycytic ependymoma described in this report was found in a 42-year-old man. Histological analysis strongly suggested that this tumor originated from a primitive progenitor cell, the ependymoglia or the tanycyte in the lateral ventricle. PMID:10667826

Daneyemez, M; Can, C; Izci, Y; Beduk, A; Timuckaynak, E

1999-12-01

488

Lateral load test of a drilled shaft in clay  

E-print Network

of shallow drilled shaft foundations. These machines had originally been used as post hole diggers by utility companies (41). It was not until truck-mounted rotary drilling machines became cemaercially available after World War II that drilled shafts...LATERAL LOAD TEST OF A DRILLED SHAFT IN CLAY A Thesis by VERNON RAY KASCH Submitted to the Graduate College of Texas A8M University in partial fulfillment of the requirement for the degree of MASTER OF SCIENCE December 1977 Major Subject...

Kasch, Vernon R

1977-01-01

489

Carbon nanotube labeled immunosensor for lateral flow diagnostics  

Microsoft Academic Search

This paper presents the development and demonstration of a new immunosensor utilizing multi-walled carbon nanotubes (MWCNTs) labeled antibodies on lateral flow system. The developed immunosensor utilizes the unique properties of carbon nanotubes coupled with highly specific biorecognition capabilities of antibodies for sensitive, low-concentration, and rapid detection mechanism. Carbon nano-tubes are excellent electrical conductors, and have chemical stability, color generation, and

Adeyabeba Abera; Jin-Woo Choi

2009-01-01

490

Examination of the Lateral Attenuation of Aircraft Noise  

NASA Technical Reports Server (NTRS)

Measurements of the lateral attenuation of noise from aircraft operations at Denver International Airport were made at distances up to 2000 feet and elevation angles up to 27 degrees. Attenuation Calculated from modem ground impedance theory agrees well with average measured attenuation. The large variability between measured and predicted levels observed at small elevation angles is demonstrated to be due to refraction by wind and temperature gradients.

Plotkin, Kenneth J.; Hobbs, Christopher M.; Bradley, Kevin A.; Shepherd, Kevin P. (Technical Monitor)

2000-01-01

491

Modeling laterally-contacted nipi-diode radioisotope batteries  

Microsoft Academic Search

A framework for modeling the power generation of laterally-contacted n-type \\/ intrinsic \\/ p-type \\/ intrinsic (nipi) diodes coupled with an alpha-particle radioisotope source is developed. The framework consists of two main parts, the alpha-particle energy deposition profile (ADEP) and a lumped parameter equivalent circuit model describing the nipi device operation. Experimental measurements are used to verify the ADEP modeling

Cory D. Cress; Brian J. Landi; Ryne P. Raffaelle

2008-01-01

492

Amyotrophic Lateral Sclerosis Multiprotein Biomarkers in Peripheral Blood Mononuclear Cells  

Microsoft Academic Search

BackgroundAmyotrophic lateral sclerosis (ALS) is a fatal progressive motor neuron disease, for which there are still no diagnostic\\/prognostic test and therapy. Specific molecular biomarkers are urgently needed to facilitate clinical studies and speed up the development of effective treatments.Methodology\\/Principal FindingsWe used a two-dimensional difference in gel electrophoresis approach to identify in easily accessible clinical samples, peripheral blood mononuclear cells (PBMC),

Giovanni Nardo; Silvia Pozzi; Mauro Pignataro; Eliana Lauranzano; Giorgia Spano; Silvia Garbelli; Stefania Mantovani; Kalliopi Marinou; Laura Papetti; Marta Monteforte; Valter Torri; Luca Paris; Gianfranco Bazzoni; Christian Lunetta; Massimo Corbo; Gabriele Mora; Caterina Bendotti; Valentina Bonetto; Harish Pant

2011-01-01

493

Motor Lateralization is characterized by a serial hybrid control scheme  

PubMed Central

Our previous studies of limb coordination in healthy right and left-handers led to the development of a theoretical model of motor lateralization, dynamic dominance, which was recently supported by studies in patients with unilateral stroke (For Review, see Sainburg, 2010: Lateralization of Goal-Directed Movements, in Human Kinetics). One of our most robust findings was on single joint movements in young healthy subjects (Sainburg and Schaefer, 2004: Interlimb differences in control of movement extent). In this study, subjects made elbow joint reaching movements toward 4 targets of different amplitudes with each arm. Whereas, both arms achieved equivalent task performance, each did so through different strategies. The dominant arm strategy scaled peak acceleration with peak velocity and movement extent, while the nondominant strategy adjusted acceleration duration to achieve the different velocities and distances. We now propose that these observed interlimb differences can be explained using a serial hybrid controller, in which movements are initiated using predictive control and terminated using impedance control. Further, we propose that the two arms should differ in the relative time that control switches from the predictive to the impedance mechanisms. We present a mathematical formulation of our hybrid controller and then test the plausibility of this control paradigm by investigating how well our model can explain interlimb differences in experimental data. Our findings confirm that the model predicts early shifts between controllers for left arm movements, which rely on impedance control mechanisms, and late shifts for right arm movements, which rely on predictive control mechanisms. This is the first computational model of motor lateralization, and is consistent with our theoretical model that emerged from empirical findings. It represents a first step in consolidating our theoretical understanding of motor lateralization into an operational model of control. PMID:21889579

Yadav, V.; Sainburg, R.L.

2011-01-01

494

Change in Perceived Age in Middle and Later Life  

ERIC Educational Resources Information Center

Analyses examine change in the age people "feel" ("felt age") and "would like to be" ("ideal age") (relative to current age) in middle and later life. Data are from 1,815 respondents in two waves (1995-96, 2004-06) of the Midlife in the United States Survey (MIDUS) who were age 40+ at Wave 1. In aggregate, people feel about the same amount younger…

Ward, Russell A.

2013-01-01

495

High-speed Germanium-on-SOI lateral PIN photodiodes  

Microsoft Academic Search

We report the fabrication and characterization of high-speed germanium on silicon-on-insulator lateral PIN photodetectors. At an incident wavelength of 850 nm, 10 ×10-?m detectors with finger spacing S of 0.4 ?m (0.6 ?m) produced a -3-dB bandwidth of 29 GHz (27 GHz) at a bias voltage of -1 V. The detectors with S=0.6 ?m had external quantum efficiency of 34%

G. Dehlinger; S. J. Koester; J. D. Schaub; J. O. Chu; Q. C. Ouyang; A. Grill

2004-01-01

496

Microstructural development in sequential lateral solidification of thin silicon films  

NASA Astrophysics Data System (ADS)

Sequential lateral solidification (SLS) is a pulsed excimer-laser crystallization process that is compatible with high-temperature intolerant substrates and that permits flexible control of grain boundary placement during iterative lateral crystal growth of thin Si films; this capability can be used to produce low-defect-density crystalline Si films with precisely engineered microstructures. A variety of intragrain planar defects are identified and characterized within the SLS-processed amorphous Si films, with sub-grain boundaries being the major intragrain defect (microtwin rich sub-grains are also found to be prevalent within the SLS-processed films). Such defects can only degrade the performance of microelectronic devices fabricated using the SLS-processed films. Single-crystal silicon-on-insulator (SOI) films are further utilized as the seed material for lateral epitaxial growth in order to systematically investigate the mechanisms that lead to the generation of these defects. The primary focus is on examining the generation of sub-grain boundaries that result from SLS processing, although it is found that the mechanisms that lead to the formation of sub-grain boundaries are also similar, if not identical, to those that lead to the formation of microtwin-rich regions. Implications of these results are discussed in relation to a plastic deformation model that is proposed to relate the formation of sub-grain boundaries in SLS-processed Si films to thermally-induced stresses that are present during the process.

Crowder, Mark A.