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1

Contours of the hominoid lateral tibial condyle with implications for Australopithecus  

Microsoft Academic Search

Tibial condyle shape is alleged to vary among fossil tibiae attributed to Australopithecus, and has been argued to reflect functional differences of the knee. Convex anteroposterior curvature of the lateral tibial condyle in A. africanus has been interpreted to indicate a more chimpanzee-like locomotor repertoire than the flatter lateral tibial condyles of A. afarensis (Berger and Tobias, 1996, J. Hum.

Jason M. Organ; Carol V. Ward

2006-01-01

2

Painful lateral knee condyle bone marrow edema after treatment with lateral wedged insole.  

PubMed

A 50-yr-old man arrived at our department for a rehabilitation prescription after a right knee medial collateral ligament sprain. Magnetic resonance imaging showed medial collateral ligament partial rupture and medial femoral condyle increased signal intensity indicating bone edema. After treatment, the patient still complained of weight-bearing knee medial compartment pain. A lateral wedged insole was prescribed to decrease medial compartment compression forces. Initial response to insole use was good, but soon after, the patient complained of severe worsening knee pain. On examination, the lateral joint line and condyle palpation were tender. Insole use discontinuation was recommended, and another magnetic resonance imaging scan was performed. It showed an high T2-weighted signal intensity, representing bone marrow edema comprising a volume of 5 x 5 x 4.5 cm of lateral femoral condyle. Discontinuation of orthosis use relieved the pain, and the edema disappeared. To our knowledge, lateral femoral condyle painful bone marrow edema after lateral wedged insole use has not been previously described. The findings of this case report indicate that lateral wedged insole prescription should be carefully evaluated. PMID:20407310

Chaler, Joaquim; Torra, Mercč; Dolz, Josep Lluís; Müller, Bertram; Garreta, Roser

2010-05-01

3

Reduction of superior-lateral intact mandibular condyle dislocation with bone traction hook.  

PubMed

Lateral and superior-lateral dislocations of the intact condyle are a rare complication, following traumatic insult to the mandible. We report an unusual case of a 54-year-old male patient who experienced both types of dislocations of the intact condyles with symphysis fracture following a road-traffic accident. Under general anesthesia, conventional manipulation was unsuccessful in relocating the condyles into the glenoid fossa. After applying a percutaneous traction force, using a bone traction hook placed at the sigmoid notch, the displaced intact mandibular condyles were repositioned, and the symphyseal fracture was finally reduced and fixed. The mouth opening was within normal limits, and favorable occlusion was confirmed one month postoperatively. To our knowledge, this is the first case of dislocation of both intact condyles--associated with symphysis fracture--being reduced with bone traction hook. PMID:24471051

Kim, Bong Chul; Kang Samayoa, Sara Rebeca; Kim, Hyung Jun

2013-10-01

4

Reduction of superior-lateral intact mandibular condyle dislocation with bone traction hook  

PubMed Central

Lateral and superior-lateral dislocations of the intact condyle are a rare complication, following traumatic insult to the mandible. We report an unusual case of a 54-year-old male patient who experienced both types of dislocations of the intact condyles with symphysis fracture following a road-traffic accident. Under general anesthesia, conventional manipulation was unsuccessful in relocating the condyles into the glenoid fossa. After applying a percutaneous traction force, using a bone traction hook placed at the sigmoid notch, the displaced intact mandibular condyles were repositioned, and the symphyseal fracture was finally reduced and fixed. The mouth opening was within normal limits, and favorable occlusion was confirmed one month postoperatively. To our knowledge, this is the first case of dislocation of both intact condyles--associated with symphysis fracture--being reduced with bone traction hook. PMID:24471051

Kim, Bong Chul; Kang Samayoa, Sara Rebeca

2013-01-01

5

Selective lateral muscle activation in moderate medial knee osteoarthritis subjects does not unload medial knee condyle  

E-print Network

Selective lateral muscle activation in moderate medial knee osteoarthritis subjects does not unload medial knee condyle Scott C.E. Brandon a,n , Ross H. Miller a , Darryl G. Thelen b , Kevin J. Deluzio Model Knee Contact a b s t r a c t There is some debate in the literature regarding the role

Wisconsin at Madison, University of

6

Two Patients with Osteochondral Injury of the Weight-Bearing Portion of the Lateral Femoral Condyle Associated with Lateral Dislocation of the Patella  

PubMed Central

Complications of patellar dislocation include osteochondral injury of the lateral femoral condyle and patella. Most cases of osteochondral injury occur in the anterior region, which is the non-weight-bearing portion of the lateral femoral condyle. We describe two patients with osteochondral injury of the weight-bearing surface of the lateral femoral condyle associated with lateral dislocation of the patella. The patients were 18- and 11-year-old females. Osteochondral injury occurred on the weight-bearing surface distal to the lateral femoral condyle. The presence of a free osteochondral fragment and osteochondral injury of the lateral femoral condyle was confirmed on MRI and reconstruction CT scan. Treatment consisted of osteochondral fragment fixation or microfracture, as well as patellar stabilization. Osteochondral injury was present in the weight-bearing portion of the lateral femoral condyle in both patients, suggesting that the injury was caused by friction between the patella and lateral femoral condyle when the patella was dislocated or reduced at about 90° flexion of the knee joint. These findings indicate that patellar dislocation may occur and osteochondral injury may extend to the weight-bearing portion of the femur even in deep flexion, when the patella is stabilized on the bones of the femoral groove. PMID:25506015

Inoue, Hiroaki; Atsumi, Satoru; Ichimaru, Shohei; Fujiwara, Hiroyoshi; Kubo, Toshikazu

2014-01-01

7

Pitfalls of lateral external fixation for supracondylar humeral fractures in children  

Microsoft Academic Search

Introduction  Closed reduction and percutaneous pinning is a standard treatment for dislocated supracondylar humeral fractures in children.\\u000a However, the management of these fractures remains challenging. The aim of this study was to evaluate lateral external fixation\\u000a as a treatment alternative for these fractures.\\u000a \\u000a \\u000a \\u000a \\u000a Materials and methods  All supracondylar fractures treated with lateral external fixation between 2005 and 2007 were evaluated retrospectively. Long-term

M. Horst; S. Altermatt; D. M. Weber; R. Weil; L. E. Ramseier

8

Quantitative proteomics reveals regulatory differences in the chondrocyte secretome from human medial and lateral femoral condyles in osteoarthritic patients  

PubMed Central

Background Osteoarthritis (OA) is a destructive joint disease and there are no known biomarkers available for an early diagnosis. To identify potential disease biomarkers and gain further insight into the disease mechanisms of OA we applied quantitative proteomics with SILAC technology on the secretomes from chondrocytes of OA knees, designated as high Mankin (HM) scored secretome. A quantitative comparison was made between the secretomes of the medial and lateral femur condyle chondrocytes in the same knee since the medial femur condyle is usually more affected in OA than the lateral condyle, which was confirmed by Mankin scoring. The medial/lateral comparison was also made on the secretomes from chondrocytes taken from one individual with no clinically apparent joint-disease, designated as low Mankin (LM) scored secretome. Results We identified 825 proteins in the HM secretome and 69 of these showed differential expression when comparing the medial and lateral femoral compartment. The LM scored femoral condyle showed early signs of OA in the medial compartment as assessed by Mankin score. We here report the identification and relative quantification of several proteins of interest for the OA disease mechanism e.g. CYTL1, DMD and STAB1 together with putative early disease markers e.g. TIMP1, PPP2CA and B2M. Conclusions The present study reveals differences in protein abundance between medial/lateral femur condyles in OA patients. These regulatory differences expand the knowledge regarding OA disease markers and mechanisms. PMID:24090399

2013-01-01

9

Lateral condyle fracture of the humerus in children treated with bioabsorbable materials.  

PubMed

The aim of this study was to compare clinical and radiological outcome of lateral condyle fracture of the elbow in children treated with bioabsorbable or metallic material. From January 2008 to December 2009, 16 children with similar fractures and ages were grouped according to the fixation material used. Children were seen at 3, 6, and 12 months and more than 4 years (mean 51.8 months) postoperatively. The clinical results were compared using the Mayo Elbow Performance Score (MEPS). Radiographic studies of the fractured and opposite elbow were assessed at last follow-up control. Twelve children had a sufficient followup and could be included in the study. Seven could be included in the traditional group and 5 in the bioabsorbable group. At 12 months, the MEPS was 100 for every child in both groups. Asymptomatic bony radiolucent visible tracks and heterotopic ossifications were noted in both groups. There were no significant differences in terms of clinical and radiological outcome between the two groups. The use of bioabsorbable pins or screws is a reasonable alternative to the traditional use of metallic materials for the treatment of lateral condyle fracture of the elbow in children. PMID:24228016

Andrey, Véronique; Tercier, Stéphane; Vauclair, Frédéric; Bregou-Bourgeois, Aline; Lutz, Nicolas; Zambelli, Pierre-Yves

2013-01-01

10

Displaced osteochondral fracture of the lateral femoral condyle associated with an acute anterior cruciate ligament avulsion fracture: a corollary of "the lateral femoral notch sign".  

PubMed

Anterior cruciate ligament (ACL) rupture is usually accompanied by bone contusions resulting from impact of tibia on femur. The injury sometimes becomes manifest as a depression on the lateral femoral condyle giving rise to "lateral femoral notch" sign. The authors describe a rare case of impaction of the tibia and femur resulting in an osteochondral fracture rather than the usual bone contusion, which frequently occurs with ACL rupture. Open reduction and internal fixation of both the ACL avulsion fracture and the osteochondral fracture from the lateral femoral condyle were done, and the patient had a good outcome at 1-year follow-up. Level of evidence V. PMID:22113226

Sharma, Gaurav; Naik, V Anand; Pankaj, Amite

2012-08-01

11

Transient Patellar Dislocation Resulting in Simultaneous Osteochondral Fractures of Patella and Lateral Femoral Condyle – A Case Report  

PubMed Central

Transient Patellar dislocations are commonly associated with bony contusions or osteochondral fractures involving the medial facet of patella or lateral femoral condyle. Simultaneous osteochondral fractures are rare and have not been reported in the adult. The authors report a case of combined osteochondral fracture of patella and lateral femoral condyle following acute patellar dislocation in an adult, which was misdiagnosed as meniscal injury. Both the osteochondral fracture fragments were rigidly fixed with headless compression screws and repair of the medial retinaculum was done. At latest follow up after two years, patient had regained full range of motion with no further episodes of patellar dislocation. The rarity of this combination of injury along with difficulty in interpreting radiographs makes this case interesting. PMID:25478378

Morey, Vivek Machhindra; Mittal, Ravi; Pannu, Chaitanya Dev

2014-01-01

12

The prevalence and causation of tennis elbow (lateral humeral epicondylitis) in a population of workers in an engineering industry  

Microsoft Academic Search

Lateral humeral epicondylitis (tennis elbow) is often considered to be work related but the incidence and prevalence among industrial workers has not previously been studiedIn this study the prevalence of this condition and its relationship to some work factors was investigated in 540 workers in a modern engineering industryThe prevalence was 7-4% (40\\/540). Work was found to be the probable

LENNART DIMBERG

1987-01-01

13

Outcome of lateral humeral condylar mass fractures in children associated with elbow dislocation or olecranon fracture  

PubMed Central

Of 2,502 elbow/humeral injuries treated at our department between 1990 and 2005, we identified a cohort of 20 lateral condylar mass (LCM) fractures of the humerus in children associated with elbow dislocation (n?=?12; mean age 8.2 years) or with olecranon fracture (n?=?8; mean age 4.1 years). Eight patients with undisplaced fracture pattern were treated conservatively yielding a satisfactory outcome. Good to excellent results were obtained in the majority (85%). Overall, the result was poor in three patients (15%; 25% of the operated cohort) due to terminal 20–30° loss of extension. There was no obvious difference in the outcome between the isolated displaced LCM fractures described in the literature and this cohort. Testing of elbow stability by examination under anaesthesia is stressed. Undisplaced fracture patterns need to be closely observed. Parents should be warned about the likelihood of some degree of unfavourable outcome in the displaced LCM fractures with associated elbow injuries. PMID:17940766

Sibinski, M.; Sherlock, D. A.

2007-01-01

14

Comparative study of depth-dependent characteristics of equine and human osteochondral tissue from the medial and lateral femoral condyles.  

PubMed

Articular cartilage defects are common after joint injuries. When left untreated, the biomechanical protective function of cartilage is gradually lost, making the joint more susceptible to further damage, causing progressive loss of joint function and eventually osteoarthritis (OA). In the process of translating promising tissue-engineering cartilage repair approaches from bench to bedside, pre-clinical animal models including mice, rabbits, goats, and horses, are widely used. The equine species is becoming an increasingly popular model for the in vivo evaluation of regenerative orthopaedic approaches. As there is also an increasing body of evidence suggesting that successful lasting tissue reconstruction requires an implant that mimics natural tissue organization, it is imperative that depth-dependent characteristics of equine osteochondral tissue are known, to assess to what extent they resemble those in humans. Therefore, osteochondral cores (4-8 mm) were obtained from the medial and lateral femoral condyles of equine and human donors. Cores were processed for histology and for biochemical quantification of DNA, glycosaminoglycan (GAG) and collagen content. Equine and human osteochondral tissues possess similar geometrical (thickness) and organizational (GAG, collagen and DNA distribution with depth) features. These comparable trends further underscore the validity of the equine model for the evaluation of regenerative approaches for articular cartilage. PMID:22781206

Malda, J; Benders, K E M; Klein, T J; de Grauw, J C; Kik, M J L; Hutmacher, D W; Saris, D B F; van Weeren, P R; Dhert, W J A

2012-10-01

15

Histological and molecular characterisation of feline humeral condylar osteoarthritis  

PubMed Central

Background Osteoarthritis (OA) is a clinically important and common disease of older cats. The pathological changes and molecular mechanisms which underpin the disease have yet to be described. In this study we evaluated selected histological and transcriptomic measures in the articular cartilage and subchondral bone (SCB) of the humeral condyle of cats with or without OA. Results The histomorphometric changes in humeral condyle were concentrated in the medial aspect of the condyle. Cats with OA had a reduction in articular chondrocyte density, an increase in the histopathological score of the articular cartilage and a decrease in the SCB porosity of the medial part of the humeral condyle. An increase in LUM gene expression was observed in OA cartilage from the medial part of the humeral condyle. Conclusions Histopathological changes identified in OA of the feline humeral condyle appear to primarily affect the medial aspect of the joint. Histological changes suggest that SCB is involved in the OA process in cats. Differentiating which changes represent OA rather than the aging process, or the effects of obesity and or bodyweight requires further investigation. PMID:23731511

2013-01-01

16

Bifid Hyperplastic Mandibular Condyle  

Microsoft Academic Search

Condylar hyperplasia is a rare non-neoplastic pathology associated with overgrowth of the mandibular condyle. Presentation\\u000a of condylar hyperplasia with bifid mandibular condyle has never been reported in literature. Early management of the hyperplastic\\u000a disorders of the mandibular condyle can prevent occlusal canting and developing asymmetric deformities. We report a case of\\u000a ‘Bifid Hyperplastic Mandibular Condyle’ in a 14-year-old male with

R. S. Neelakandan; Darpan Bhargava

17

Decreased scapular notching with lateralization and inferior baseplate placement in reverse shoulder arthroplasty with high humeral inclination  

PubMed Central

Background: Scapular notching is a radiographic finding of unknown clinical significance following reverse total shoulder arthroplasty (RTSA). The purpose of this study was to determine how baseplate position affects the incidence of scapular notching and measure the clinical outcomes. Hypothesis: We hypothesized that low base plate position on the glenoid and new prosthesis design with a higher humeral inclination angle would decrease the incidence of notching at 2 years follow-up. Materials and methods: A total of 54 patients with an average follow-up of 30 months met inclusion criteria and underwent radiographic analysis of scapular notching and radiographic measures to determine glenoid component placement. Clinical measures including visual analog score, American Shoulder and Elbow Surgeons (ASES) scores, and range of motion (ROM) were prospectively collected. Results: Thirty-nine of the 54 patients had no notching. 7 had Grade 1 notching, 7 had Grade 2 notching, one had Grade 3, and one had Grade 4 notching. Notching was associated with higher placement of the glenoid component as measured by peg-glenoid rim distance and base plate distance. All patients with no evidence of notching at 1-year, continued to have no notching after multi-year follow-up. Clinical outcome measures including ASES scores, ROM, and visual analog pain scores were improved at follow-up. Conclusion: We concluded that lower neck-shaft angle and low baseplate positioning led to a low incidence of significant scapular notching as only 6 out of 57 (16%) patients had notching Grade 2 and above. At short-term follow-up, this RTSA results in excellent clinical outcomes and a significantly lower scapular notching rate than traditional techniques. PMID:25258496

Feeley, Brian T.; Zhang, Alan L.; Barry, Jeffery J.; Shin, Edward; Ho, Julianne; Tabaraee, Ehsan; Ma, C. Benjamin

2014-01-01

18

Bone peg fixation of a large chondral fragment in the weight-bearing portion of the lateral femoral condyle in an adolescent: a case report  

PubMed Central

Introduction Chondral fracture of the knee is relatively rare and the optimal treatment option for this injury is still controversial. In this report, we present the case of a patient with this injury who was treated surgically using the bone peg fixation procedure. There has been no literature reporting the use of this technique for fixation of a detached chondral fragment. Case presentation The patient was a 14-year-old Japanese boy who sustained a knee injury while kicking a soccer ball. Although routine radiographs showed no abnormality, magnetic resonance imaging showed a large full-thickness chondral defect in the weight-bearing portion of his lateral femoral condyle and a detached chondral fragment in the anterior region. The size of the defect (fragment) was 2cm by 1.5cm. At surgery, the chondral fragment was fixed with eight cortical bone pegs that were harvested from the anteromedial aspect of his tibia. Conclusions The postoperative magnetic resonance imaging at 4 months and the second-look arthroscopy at 12 months revealed apparent healing of the fragment. In the final follow-up examination at 26 months, a physical examination showed no swelling with recovery of full range of motion, and he could play soccer at the pre-injury level with no complaint. Based on the clinical course of this patient, it is thought that bone peg fixation can be a valuable option for fixation of a large chondral fracture of the knee. PMID:25248689

2014-01-01

19

Bilateral Occipital Condyle Fracture  

PubMed Central

Occipital condyle fractures are a rare finding in trauma victims. Bilateral fractures are even more unusual and have typically been reported in autopsy studies. We treated two patients with bilateral occipital condyle fractures who had only minor symptoms. Anderson and Montesano's classification,1 possible cranial nerve palsies, diagnosis, and treatment of this rare fracture are discussed. ImagesFigure 1Figure 2 PMID:17167657

Schrödel, Markus H.; Kestlmeier, Ralph; Trappe, Anna E.

2002-01-01

20

Hypoplastic occipital condyle and third occipital condyle: review of their dysembryology.  

PubMed

Disruption or embryologic derailment of the normal bony architecture of the craniovertebral junction (CVJ) may result in symptoms. As studies of the embryology and pathology of hypoplasia of the occipital condyles and third occipital condyles are lacking in the literature, the present review was performed. Standard search engines were accessed and queried for publications regarding hypoplastic occipital condyles and third occipital condyles. The literature supports the notion that occipital condyle hypoplasia and a third occipital condyle are due to malformation or persistence of the proatlas, respectively. The Pax-1 gene is most likely involved in this process. Clinically, condylar hypoplasia may narrow the foramen magnum and lead to lateral medullary compression. Additionally, this maldevelopment can result in transient vertebral artery compression secondary to posterior subluxation of the occiput. Third occipital condyles have been associated with cervical canal stenosis, hypoplasia of the dens, transverse ligament laxity, and atlanto-axial instability causing acute and chronic spinal cord compression. Treatment goals are focused on craniovertebral stability. A better understanding of the embryology and pathology related to CVJ anomalies is useful to the clinician treating patients presenting with these entities. PMID:23338989

Tubbs, R Shane; Lingo, Patrick Ryan; Mortazavi, Martin M; Cohen-Gadol, Aaron A

2013-11-01

21

Osteochondroma of the mandibular condyle.  

PubMed

Osteochondroma is one of the most common benign tumors of the axial skeleton, but is rarely found in the facial bones. When present, the tumor is most often reported to affect the mandibular coronoid process. Osteochondroma of the mandibular condyle is extremely rare. A case is presented of a massive osteochondroma of the mandibular condyle leading to facial asymmetry and disturbed occlusion. The diagnosis was confirmed by radiological and histological examination. PMID:12682692

Ongole, Ravikiran; Pillai, Rajeev S; Ahsan, Auswaf K; Pai, Keerthilatha M

2003-02-01

22

Double crush syndrome due to plating of humeral shaft fracture  

PubMed Central

Median nerve injury is rarely associated with the humeral shaft fracture. A Sixty two year old woman with a displaced humeral shaft fracture, developed a symptomatic carpal tunnel syndrome after plating with a screw protruding medially. 16 months later, the implants were removed and the symptoms gradually improved without carpal tunnel release surgery. A double crush syndrome resulted due to the proximal compression by the medially protruding screw and the distal compression by carpal tunnel. The proximal decompression produced by removal of the screw led to relief of the symptoms. PMID:24741148

Huang, Yi-Gang; Chang, Shi-Min

2014-01-01

23

Central chondrosarcoma of a pediatric mandibular condyle: A case report and review  

PubMed Central

Chondrosarcoma of mandibular condyle is an extremely rare clinical entity with only 18 cases reported till date. We report a rare case of central myxoid chondrosarcoma in a 7 year old male child with a complaint of slow growing bony hard swelling of left mandibular condyle. Panoramic radiography and CT scan revealed a 5×3cm osteosclerotic and osteolytic lesion with cortical perforation on the medial side of the left mandibular condyle with a cortical expansion of lateral side. Segmental mandibulectomy with disarticulation of the left condyle was done. To the best of our knowledge it is the first case of chondrosarcoma of the paediatric mandibular condyle to be reported. The etiopathogenesis, clinical, radiological diagnosis and various treatment modalities of chondrosarcoma are discussed PMID:24987606

Kumar Reddy, D. Sathya; Kishore Kumar, R. V.; Gali, Rajasekhar; Kannubaddy, Sridhar Reddy; Rao, Mallikarjuna; Akheel, Mohammad

2014-01-01

24

Archaic and modern human distal humeral morphology.  

PubMed

The morphology of the proximal ulna has been shown to effectively differentiate archaic or premodern humans (such as Homo heidelbergensis and H. neanderthalensis) from modern humans (H. sapiens). Accordingly, the morphology of adjacent, articulating elements should be able to distinguish these two broad groups as well. Here we test the taxonomic utility of another portion of the elbow, the distal humerus, as a discriminator of archaic and modern humans. Principal components analysis was employed on a suite of log-raw and log-shape distal humeral measures to examine differences between Neandertal and modern human distal humeri. In addition, the morphological affinities of Broken Hill (Kabwe) E.898, an archaic human distal humeral fragment from the middle Pleistocene of Zambia, and five Pliocene and early Pleistocene australopith humeri were assessed. The morphometric analyses effectively differentiated the Neandertals from the other groups, while the Broken Hill humerus appears morphologically similar to modern human distal humeri. Thus, an archaic/modern human dichotomy-as previously reported for proximal ulnar morphology-is not supported with respect to distal humeral morphology. Relative to australopiths and modern humans, Neandertal humeri are characterized by large olecranon fossae and small distodorsal medial and lateral pillars. The seeming disparity in morphological affinities of proximal ulnae (in which all archaic human groups appear distinct from modern humans) and distal humeri (in which Neandertals appear distinct from modern humans, but other archaic humans do not) is probably indicative of a highly variable, possibly transitional population of which our knowledge is hampered by sample-size limitations imposed by the scarcity of middle-to-late Pleistocene premodern human fossils outside of Europe. PMID:16959299

Yokley, Todd R; Churchill, Steven E

2006-12-01

25

21 CFR 872.3960 - Mandibular condyle prosthesis.  

Code of Federal Regulations, 2011 CFR

...2011-04-01 false Mandibular condyle prosthesis. 872.3960 Section 872.3960... § 872.3960 Mandibular condyle prosthesis. (a) Identification. A mandibular condyle prosthesis is a device that is intended to...

2011-04-01

26

21 CFR 872.3960 - Mandibular condyle prosthesis.  

Code of Federal Regulations, 2014 CFR

...2014-04-01 false Mandibular condyle prosthesis. 872.3960 Section 872.3960... § 872.3960 Mandibular condyle prosthesis. (a) Identification. A mandibular condyle prosthesis is a device that is intended to...

2014-04-01

27

Proximal humeral nonunion treated with an intramedullary tantalum cylinder.  

PubMed

Nonunion is uncommon after proximal humerus fracture surgery. There is no agreement about preferred method of treatment. Traditional approaches have included laterally based locking plates, autogenous grafting, and endosteal support to provide improved biomechanical stability. Open reduction and internal fixation (ORIF) of proximal humeral nonunion has been performed with various methods, including blade plates and bone grafting, as well as intramedullary support with autologous or allogenic grafts. Both malunion and nonunion have occurred after ORIF with locking plates. Endosteal support in the form of a fibular allograft incorporated into the locking plate construct can increase mechanical stability in selected cases. An ideal implant for proximal humeral nonunion provides medial column mechanical support and osteoconductive and osteoinductive properties. Porous intramedullary tantalum metal may play a role in nonunion surgery as an alternative to fibular allograft because of its versatility of use and salutary biological effects. It offers many material advantages for use in nonunion surgery. Tantalum is extensively porous (75%-80%), has a stiffness close to that of native bone, and offers the possibility of being a carrier for osteoinductive materials. It may also be suitable for patients who refuse allograft material. This article describes a 65-year-old woman with recalcitrant proximal humeral nonunion who was successfully treated with revision ORIF with intramedullary tantalum cylinder augmentation with a lateral-based locking plate and autogenous cancellous bone grafting. At 5-year follow-up, she had excellent motion and clinical and radiographic union. PMID:24579230

Georgiadis, Gregory M; Georgiadis, Andrew G

2013-12-01

28

Nonunion of the humeral shaft.  

PubMed

Retrospective review of records of 26 patients with nonunion of the humeral shaft revealed several factors frequently associated with the development of nonunion. The fractures were transverse and short oblique and treated per primam with hanging casts or open reduction. Surgical fixation was unstable. The types of nonunion were atrophic in 19 patients, hypertrophic in five patients, and synovial pseudarthrosis in two patients. Twenty-four of 26 nonunions (92%) treated with bone grafts and rigid internal fixation healed in an average of 5.6 months. Overall, 47 surgical procedures, including prior procedures, were performed on these 26 nonunions. The average number of operations per patient was 1.8. Successful platings produced immobilization, consisting of an average of 6.8 points of cortical fixation above the nonunion and 7.1 cortices below. Rigid fixation was not obtained in the unsuccessful procedures. Unsuccessful platings were noted to have unstable fixation, with an average of 2.7 points of cortical fixation above the nonunion and 3.0 cortices below. Bone grafting was performed in only 55% of the unsuccessful platings. Optimal treatment of nonunions of the humeral shaft consists of resecting atrophic nonunions, shortening the bones, drilling sclerotic areas, and apposing bleeding diaphyseal surfaces; open reduction with internal fixation with a broad compression plate, including at least six points of cortical fixation above and below the nonunion; compression of the nonunion by means of interfragmentary lag screws, prestressing of the plate, dynamic compression by the plate, or direct compression by the external compression device; and autogeneic cancellous iliac bone grafts. PMID:3555925

Healy, W L; White, G M; Mick, C A; Brooker, A F; Weiland, A J

1987-06-01

29

Isolated humeral metastasis in uterine cervical cancer: a rare entity.  

PubMed

Bone metastasis in cancer of uterine cervix, especially in the form of isolated bone involvement is a rare manifestation. Herein, we report the first case of isolated humeral metastasis in a known case of locally advanced cervical cancer. A fifty-six-year old female presented with International Federation of Gynecology and Obstetrics (FIGO) Stage IV A squamous cell carcinoma of uterine cervix. She was treated with a combination of radiation and chemotherapy and then total abdominal hysterectomy with bilateral salpingo-oophorectomy. Seven months later, she developed an isolated lytic lesion in the left humerus, which turned out to be a bone metastatic lesion. PMID:23393636

Malek, Mahrooz; Kanafi, Alireza Rajabzadeh; Pourghorban, Ramin; Nafisi-Moghadam, Reza

2012-01-01

30

Hominoid humeral morphology: 3D morphometric analysis.  

PubMed

Variation in humeral morphology among hominoids has long been recognized in relation to both phylogeny and behavior. Here, we use 3D landmark data to analyze humeral shape among hominoids, including hylobatids (n?=?37), Pongo (n?=?33), Homo (n?=?74), Pan (n?=?55), and Gorilla (n?=?45) to examine the relative influence of phylogenetic history vs. locomotor adaptation on humeral shape. Principal components analysis (PCA) of Procrustes shape data derived from 19 humeral type II or type III landmarks (Bookstein, 1991) for these taxa reveals the following: PC1, which primarily reflects the humeral torsion (or lack thereof) and relative diaphyseal and epiphyseal breadths, separates the relatively narrow-shafted, small articular dimensions and low humeral torsion Hylobates, and to a lesser extent, Pongo, humeri from those of the African hominoids. PC2, which largely contrasts shafts that are posteriorly convex (high PC2 scores) with antero-posteriorly straight humeral shafts (low PC2 scores) separates Homo, who tend to have A-P straighter shafts, from the more A-P bowed humeral shafts of the apes. These shape patterns suggest that the bowed shafts of Pan, Pongo, and Gorilla (and to a lesser extent, hylobatids) are due to the fact that in each of these taxa, the humerus is a weight-bearing bone, whereas the shafts of Homo are freed from locomotion. More subtle behavioral indicators are also elucidated, whereas cluster analyses (minimum spanning tree fit to a principal coordinates [PCO] plot and UPGMA dendrogram) reveal strong phylogenetic signals in the hominoid humerus as well. PMID:24132859

Holliday, Trenton W; Friedl, Lukáš

2013-12-01

31

21 CFR 872.3960 - Mandibular condyle prosthesis.  

Code of Federal Regulations, 2012 CFR

... FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES DENTAL DEVICES Prosthetic Devices § 872.3960 Mandibular condyle prosthesis. (a) Identification. A mandibular condyle prosthesis...

2012-04-01

32

21 CFR 872.3960 - Mandibular condyle prosthesis.  

Code of Federal Regulations, 2010 CFR

... FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES DENTAL DEVICES Prosthetic Devices § 872.3960 Mandibular condyle prosthesis. (a) Identification. A mandibular condyle prosthesis...

2010-04-01

33

21 CFR 872.3960 - Mandibular condyle prosthesis.  

Code of Federal Regulations, 2013 CFR

... FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES DENTAL DEVICES Prosthetic Devices § 872.3960 Mandibular condyle prosthesis. (a) Identification. A mandibular condyle prosthesis...

2013-04-01

34

Mandibular condyle traits in Neanderthals and other Homo: a comparative, correlative, and ontogenetic study.  

PubMed

The relationship between the mandibular condyle and the crest of the mandibular notch (CMN) has historically entered into discussions of Neanderthal characteristics and was recently suggested to be autapomorphic in Neanderthals. The Neanderthal CMN has been described as intersecting the condyle in the middle, while the modern human CMN runs to the condyle's lateral end. A large lateral condylar tubercle (LCT) has also been observed in Neanderthals and thought to be related to medial (or less lateral) CMN position. In addition, the presence of a less lateral CMN early in ontogeny, as seen in the Amud 7 infant, has been argued to demonstrate great evolutionary divergence in Neanderthals. Using a scoring system for each trait, this study first examines the expression of CMN position and LCT size in 102 adult modern humans and in samples of Neanderthals and other fossil Homo. Then, CMN position is scored in 208 subadult modern humans to elucidate the ontogeny of this trait. Results show that CMN position is not autapomorphic in Neanderthals, but Neanderthals have significantly more CMNs in the least-lateral score category than does the modern human sample. Large LCTs are found to be strongly predictive of less lateral CMN position, although less lateral CMN position may exist in the absence of a large LCT. The complex ontogenetic pattern of CMN expression observed indicates that features of subadult and adult condylar morphology cannot be constructively compared without first considering subadult morphology on its own functional and developmental terms. PMID:12237935

Jabbour, Rebecca S; Richards, Gary D; Anderson, John Y

2002-10-01

35

Humeral head osteonecrosis following arthroscopic rotator cuff repair.  

PubMed

Humeral head chondrolysis and osteonecrosis of the glenoid have been reported; however, there is no report to date about humeral head osteonecrosis following arthroscopic shoulder procedure. We report a case of osteonecrosis of the humeral head following arthroscopic rotator cuff repair what we believe is probably secondary to disruption of its blood supply after placement of multiple metallic suture anchors. The surgical records were also reviewed in an attempt to identify the cause of the humeral head osteonecrosis. PMID:20033673

Beauthier, V; Sanghavi, S; Roulot, E; Hardy, P

2010-10-01

36

Locked intramedullary nailing for difficult nonunions of the humeral diaphysis  

Microsoft Academic Search

Antegrade intramedullary nailing and bone grafting was carried out for 27 patients with resistant atrophic nonunion of the humeral diaphysis. The initial fracture was open in 12 cases and closed in 15. There were ten proximal humeral fractures, 13 mid-shaft fractures and four distal humeral shaft fractures. Most had previous attempts at internal fixation with bone grafting. Fifteen cases united,

I. Ilyas; D. A. Younge

2003-01-01

37

Salvage of humeral non-union by extendible total humeral endoprosthesis  

Microsoft Academic Search

We present an elderly patient with an aseptic, diaphyseal non-union of the Humerus, where other methods of management had failed. An extendible total humeral endoprosthetic replacement was used with adequate functional results.

R. J. Grimer

38

In Vivo Motion of Femoral Condyles During Weight-Bearing Flexion After Anterior Cruciate Ligament Rupture Using Biplane Radiography  

PubMed Central

The purpose of this study was to investigate in vivo three- dimensional tibiofemoral kinematics and femoral condylar motion in knees with anterior cruciate ligament (ACL) deficiency during a knee bend activity. Ten patients with unilateral ACL rupture were enrolled. Both the injured and contralateral normal knees were imaged using biplane radiography at extension and at 15°, 30°, 60°, 90°, and 120° of flexion. Bilateral knees were next scanned by computed tomography, from which bilateral three-dimensional knee models were created. The in vivo tibiofemoral motion at each flexion position was reproduced through image registration using the knee models and biplane radiographs. A joint coordinate system containing the geometric center axis of the femur was used to measure the tibiofemoral motion. In ACL deficiency, the lateral femoral condyle was located significantly more posteriorly at extension and at 15° (p < 0.05), whereas the medial condylar position was changed only slightly. This constituted greater posterior translation and external rotation of the femur relative to the tibia at extension and at 15° (p < 0.05). Furthermore, ACL deficiency led to a significantly reduced extent of posterior movement of the lateral condyle during flexion from 15° to 60° (p < 0.05). Coupled with an insignificant change in the motion of the medial condyle, the femur moved less posteriorly with reduced extent of external rotation during flexion from 15° to 60° in ACL deficiency (p < 0.05). The medial- lateral and proximal-distal translations of the medial and lateral condyles and the femoral adduction-abduction rotation were insignificantly changed after ACL deficiency. The results demonstrated that ACL deficiency primarily changed the anterior-posterior motion of the lateral condyle, producing not only posterior subluxation at low flexion positions but also reduced extent of posterior movement during flexion from 15° to 60°. Key Points Three-dimensional tibiofemoral kinematics and femoral condylar motion in ACL-deficient knees during upright weight-bearing flexion were measured using biplane radiography with the geometric center axis. ACL deficiency caused posterior subluxation of the lateral condyle with excess external femoral rotation at early flexion positions. On flexion from 15° to 60°, the lateral condyle moved slightly posteriorly in ACL deficiency leading to reduced extent of external femoral rotation. PMID:24149168

Chen, Kaining; Yin, Li; Cheng, Liangjun; Li, Chuan; Chen, Cheng; Yang, Liu

2013-01-01

39

The tricipital aponeurosis--a reliable soft tissue landmark for humeral plating.  

PubMed

This study aims to identify the relationship of the radial nerve as it descends across the humerus with reference to a reliable soft tissue landmark, the tricipital aponeurosis. Following cadaveric dissection of 10 adult humerii, the radial nerve was located as it crossed the lateral midsagittal point of the humeral diaphysis. A horizontal line was then subtended medially from this point to another line subtended vertically from the lateral border of the tricipital aponeurosis. The vertical distance from this intersection to the lateral apex of the aponeurosis was recorded in three positions (full flexion, 90° of flexion and full extension). The location of the radial nerve on the posterior aspect of the humeral diaphysis to the medial apex of the tricipital aponeurosis was also noted. In 90° of flexion the radial nerve at the lateral midsagittal point of the humerus was 0.9 mm proximal to the lateral apex of the tricipital aponeurosis. Flexion and extension of the elbow changed the interval to 16.3 mm (nerve proximal) in full flexion and 7.1 mm in full extension (nerve distal). On the posterior aspect of the humerus the radial nerve was 21.8 mm proximal to the medial aspect of the tricipital aponeurosis. The aponeurosis provides a reference point from which the nerve can be easily located on the lateral aspect of the humerus intraoperatively in a range of positions, whilst the medial apex provides a guide to the location of the nerve on the posterior aspect of the arm. PMID:25609275

McCann, P A; Smith, G C S; Clark, D; Amirfeyz, R

2015-01-01

40

Tetrafid mandibular condyle: a unique case report and review of the literature  

PubMed Central

Morphological changes such as bifid and trifid mandibular condyle are rare entities. The aim of the present report is to describe a unique morphological variation of the mandibular condyle which has four separate condylar heads (tetrafid mandibular condyle) and to discuss clinical and radiological differential diagnosis of tetrafid mandibular condyle with advanced imaging techniques. PMID:22065803

?ahman, H; Etöz, OA; ?ekerci, AE; Etöz, M; ?i?man, Y

2011-01-01

41

Unilateral humeral lengthening in children and adolescents.  

PubMed

This study evaluates our early experience with unilateral humeral lengthening in children and adolescents. From 1995 till 2001, 16 cases with unilateral humeral shortening ranging from 5.5 to 15 cm were referred to our center. The cause was Erb's palsy in eight cases, epiphyseal injury in five cases and infection in three cases. The average age at operation was 13 years (range 8.5-17 years). Hybrid fixation using wires and half pins were applied to all cases to minimize the risk of operative neurovascular complications. Osteotomy was performed in the middle third of the humerus through a posterior approach. After a latent period of 5-7 days lengthening started at a rate of 0.33 mm every 8 h. At an average follow up of 3 years and 2 months (range 1 year and 4 months to 5 years and 6 months) there were 10 excellent and six good results. The average healing index was 28 days/cm. Complications included pin tract infection in all cases; radial nerve palsy in one patient whose humerus overlengthened by 2 cm but improved completely after compression; fracture of the regenerate in two cases. PMID:16200022

Hosny, Gamal Ahmed

2005-11-01

42

Osteochondroma of condyle: case discussion and review of treatment modalities.  

PubMed

Temporomandibular joint (TMJ) forms a synovial articulation between the condyle and the cranium. It is a complex joint and shows hinge and gliding movements. Unlike other articulating heads, condyle grows with intramembranous ossification. TMJ is subjected to excessive loads throughout life as it supports essential functions such as mastication, deglutition, speech and respiration. Traumatic, neoplastic or non-neoplastic pathologies sometimes necessitate joint replacement therapy. Osteochondroma is one such benign tumour originating from condyle which requires surgical replacement of condyle with prosthesis. Various replacement methods have been designed in the past. Alloplastic grafts have been successfully used in joint replacement surgeries like hip joint, knee joint, etc. This case discussion supports the use of titanium-made condylar prosthesis for long-term functional stability of TMJ. PMID:24496065

Arora, Piyush; Deora, Shakti Singh; Kiran, Shital; Bargale, Seema Dinesh

2014-01-01

43

Treatment of osteochondritis dissecans of the femoral condyle with autologous bone grafts and matrix-supported autologous chondrocytes  

Microsoft Academic Search

The objective of this study was to determine the clinical outcome of combined bone grafting and matrix-supported autologous\\u000a chondrocyte transplantation in patients with osteochondritis dissecans of the knee. Between January 2003 and March 2005, 21\\u000a patients (mean age 29.33 years) with symptomatic osteochondritis dissecans (OCD) of the medial or lateral condyle (grade III\\u000a or IV) of the knee underwent reconstruction

Joern Steinhagen; Juergen Bruns; Georg Deuretzbacher; Wolfgang Ruether; Martin Fuerst; Oliver Niggemeyer

2010-01-01

44

Myositis ossificans of the humeral insertion of pectoralis major  

PubMed Central

We report on a rare case of myositis ossificans of the humeral insertion of pectoralis major muscle following a single episode of trauma which, to our knowledge, has not previously been documented. PMID:25114419

Mogere, Viga; Thyagarajan, David S. K.; Fairbairn, K. Julia; Wallace, Angus

2014-01-01

45

Motion of the femoral condyles in flexion and extension during a continuous lunge.  

PubMed

Numerous studies have reported on in-vivo posterior femoral condyle translations during various activities of the knee. However, no data has been reported on the knee motion during a continuous flexion-extension cycle. Further, few studies have investigated the gender variations on the knee kinematics. This study quantitatively determined femoral condylar motion of 10 male and 10 female knees during a continuous weightbearing flexion-extension cycle using two-dimensional to three-dimensional fluoroscopic tracking technique. The knees were CT-scanned to create three-dimensional models of the tibia and femur. Continuous images of each subject were taken using a single-fluoroscopic imaging system. The knee kinematics were measured along the motion path using geometric center axis of the femur. The results indicated that statistical differences between the flexion and extension motions were only found in internal-external tibial rotation and lateral femoral condylar motion at the middle range of flexion angles. At low flexion angles, male knees have greater external tibial rotation and more posteriorly positioned medial femoral condyle than females. The knee did not show a specific pivoting type of rotation with flexion. Axial rotation center varied from lateral to medial compartments of the knee. These data could provide useful information for understanding physiological motion of normal knees. © 2015 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 33:591-597, 2015. PMID:25641056

Feng, Yong; Tsai, Tsung-Yuan; Li, Jing-Sheng; Wang, Shaobai; Hu, Hai; Zhang, Changqing; Rubash, Harry E; Li, Guoan

2015-04-01

46

Osteochondroma of mandibular condyle: A clinic-radiographic correlation  

PubMed Central

Osteochondroma (OC) of temporo mandibular joint is a rare, slow growing, benign tumor that causes a progressive enlargement of the condyle, usually resulting in facial asymmetry, temporo mandibular joint (TMJ) dysfunction, limited mouth opening and malocclusion. Pain is rarely associated with this tumor. OC is composed of cartilaginous and osseous tissues. Radiographically, there is unilaterally enlarged condyle usually with an exophytic outgrowth of the tumor from the condylar head. We present a rare case of osteochondroma of right mandibular condyle in a 45-year-old male who reported with painless swelling over TMJ area and progressive limited mouth opening. Panoramic radiograph and computed tomography (CT) was performed for better evaluation of the pathological condition. This paper describes the clinico-radiographic features and differential diagnosis of OC. PMID:24082753

More, Chandramani B.; Gupta, Swati

2013-01-01

47

Orthopaedic Approaches to Proximal Humeral Fractures Following Trauma  

PubMed Central

Proximal humeral fractures have been a topic of discussion in medical literature dating back as far as 3rd century BC. Today, these fractures are the most common type of humeral fractures and account for about 5-6% of all fractures in adults with the incidence rising rapidly with age. In broad terms the management of proximal humeral fractures can be divided into two categories: conservative versus surgical intervention. The aim of treatment is to stabilize the fracture, aid better union and reduce pain during the healing process. Failure to achieve this can result in impairment of function, and significantly weaken the muscles inserting onto the proximal humerus. With the rising incidence of proximal humeral fractures, especially among the elderly, the short and long term burden for patients as well as the wider society is increasing. Furthermore, there is a lack of consistency in the definitive treatment and management of displaced fractures. This systematic review of literature compares the surgical treatment of proximal humeral fractures with their conservative management, by evaluating the available randomised controlled trials on this topic. PMID:25408786

Mafi, Reza; Khan, Wasim; Mafi, Pouya; Hindocha, Sandip

2014-01-01

48

Complaints related to mandibular function impairment after closed treatment of fractures of the mandibular condyle.  

PubMed

This study analysed the relationship between complaints and mandibular function after closed treatment of fractures of the mandibular condyle in a prospective study. In a 1-year follow-up, complaints were assessed during physical examination and function was assessed using the mandibular function impairment questionnaire (MFIQ), scoring range 0-68. Data from 114 patients (41 women, 73 men), mean age 28.1 years (SD 13.3), were available. On average the MFIQ scores were low 3.4 (SD 7.3). Ten patients (9%) experienced pain and 45 (39%) patients had a MFIQ score > 0. Mean mouth opening was 51.9 mm (SD 8.4). Occlusion was perceived as moderate or poor by 24% of the patients. In the logistic regression analysis mandibular function impairment (MFIQ score > 0) was entered as a dependent variable. Risk factors for mandibular function impairment were: pain, perceived occlusion (moderate or poor), absolute difference between left and right horizontal movements and age. A protective factor was mouth opening. The results of this study show that complaints (i.e. pain, perceived occlusion, reduced mouth opening, difference between left and right lateral movements and increased age) are predictors of mandibular function impairment after closed treatment of fractures of the mandibular condyle. PMID:20430584

Niezen, E T; Bos, R R M; de Bont, L G M; Stegenga, B; Dijkstra, P U

2010-07-01

49

Evaluation of mandibular condyles in children with unilateral posterior crossbite.  

PubMed

The relationship of mandibular condyle dimensions and its association with unilateral posterior crossbite (UPXB) has been suggested in the literature. The purpose of this prospective study was to evaluate mandibular condyles on the left and right sides and between crossed and non-crossed sides in the sagittal and coronal planes, using cone-beam computed tomography (CBCT). Twenty CBCT images of 40 temporo mandibular joints (TMJs) in individuals in mixed dentition phase, which included 9 males (mean 7.9 years) and 11 females (mean 8.2 years), with unilateral posterior crossbite without premature contacts and functional mandibular shifts and with transverse maxillary deficiency. The criteria for sample exclusion included the presence of painful symptoms, facial trauma history, systemic diseases such as juvenile rheumatoid arthritis, mouth opening limitation (< 40 mm), congenital or genetic anomalies, and skeletal asymmetries that may result in TMJ disorders. Dimensional measurements of the condyles between the right and left sides and crossed and non-crossed sides in sagittal and coronal view were made. There was no significant difference between the measurements of the crossed and non-crossed sides in both sagittal and coronal view. These findings suggest that the presence of unilateral posterior crossbite in children with UPXB did not result in changes between the mandibular condyles in the right and left sides or between the crossed and non-crossed sides in the coronal or sagittal plane. PMID:25760067

Illipronti-Filho, Edson; Fantini, Solange Mongelli; Chilvarquer, Israel

2015-03-01

50

Anterior Shoulder Dislocation and Ipsilateral Humeral Shaft Fracture  

PubMed Central

Simultaneous dislocation of shoulder and humeral shaft fracture is a rare injury, and there is no clear protocol for its treatment. Herein we present a case of a 15-year-old boy, who suffered from a job-related accident and sustained fracture of humeral shaft associated with ipsilateral anterior shoulder dislocation and fracture of greater tuberosity 15 years ago. He received closed reduction of both injuries and coaptation plaster splint for four weeks, followed by Sarmiento splint at that time. Fifteen years after the injury, he has no problem related to the previous injury, and does not experience any episode of shoulder instability. PMID:23115454

Karimi-Nasab, Mohammad Hossein; Shayesteh-Azar, Masoud; Sajjadi–Saravi, Majid; Mehdi Daneshpoor, Seyed Mohamad

2012-01-01

51

General Amphibian characteristics: 1) Two occipital condyles  

E-print Network

the populations that they function as though they were two separate, non- interbreeding species. Caecilians Order aquatic caecilians, with four genera in South America, some to 75 cm. The posterior body is laterally? Characteristics of Caecilians l Elongate, limbless, & primitively fossorial (built for burrowing)­ some

Dever, Jennifer A.

52

An inconvenient truth: Treatment of displaced paediatric supracondylar humeral fractures  

Microsoft Academic Search

The need for emergent management of displaced paediatric supracondylar humeral fractures is being questioned in the literature. Open reduction rates of up to 46% have been reported in the non-emergent management of these injuries. At our institution these fractures are managed as operative emergencies by senior personnel. To examine the ongoing need for this policy we reviewed our results. All

M. Donnelly; C. Green; I. P. Kelly

53

Metallosis and pseudotumor after failed ORIF of a humeral fracture.  

PubMed

Metallosis following open reduction and internal fixation (ORIF) for fracture, usually presenting as a soft tissue mass, is barely discussed in the literature. In this case report, the imaging and pathological findings of metallosis after ORIF for a humeral fracture are presented and comprehensively discussed. PMID:22035401

Edelstein, Yudell; Ohm, Hyunsook; Rosen, Yale

2011-01-01

54

Occipital condyle to cervical spine fixation in the pediatric population.  

PubMed

Fixation at the craniovertebral junction (CVJ) is necessary in a variety of pediatric clinical scenarios. Traditionally an occipital bone to cervical fusion is preformed, which requires a large amount of hardware to be placed on the occiput of a child. If a patient has previously undergone a posterior fossa decompression or requires a decompression at the time of the fusion procedure, it can be difficult to anchor a plate to the occipital bone. The authors propose a technique that can be used when faced with this difficult challenge by using the occipital condyle as a point of fixation for the construct. Adult cadaveric and a limited number of case studies have been published using occipital condyle (C-0) fixation. This work was adapted for the pediatric population. Between 2009 and 2012, 4 children underwent occipital condyle to axial or subaxial spine fixation. One patient had previously undergone posterior fossa surgery for tumor resection, and 1 required decompression at the time of operation. Two patients underwent preoperative deformity reduction using traction. One child had a Chiari malformation Type I. Each procedure was performed using polyaxial screw-rod constructs with intraoperative neuronavigation supplemented by a custom navigational drill guide. Smooth-shanked 3.5-mm polyaxial screws, ranging in length from 26 to 32 mm, were placed into the occipital condyles. All patients successfully underwent occipital condyle to cervical spine fixation. In 3 patients the construct extended from C-0 to C-2, and in 1 from C-0 to T-2. Patients with preoperative halo stabilization were placed in a cervical collar postoperatively. There were no new postoperative neurological deficits or vascular injuries. Each patient underwent postoperative CT, demonstrating excellent screw placement and evidence of solid fusion. Occipital condyle fixation is an effective option in pediatric patients requiring occipitocervical fusion for treatment of deformity and/or instability at the CVJ. The use of intraoperative neuronavigation allows for safe placement of screws into C-0, especially when faced with a challenging patient in whom fixation to the occipital bone is not possible or is less than ideal. PMID:24206344

Kosnik-Infinger, Libby; Glazier, Steven S; Frankel, Bruce M

2014-01-01

55

Biomechanics of the Shoulder in Youth Baseball PitchersImplications for the Development of Proximal Humeral Epiphysiolysis and Humeral Retrotorsion  

Microsoft Academic Search

Background: The effects of repetitive throwing on the shoulders of developing athletes are not well understood because of the paucity of data describing the biomechanics of youth pitchers and the plasticity of the developing skeleton.Hypothesis: The direction and magnitude of the stresses that exist at the proximal humeral physis during the fastball pitching motion are consistent with the development of

Michelle B. Sabick; Young-Kyu Kim; Michael R. Torry; Michael A. Keirns; Richard J. Hawkins

2005-01-01

56

Effect of screw placement on fixation in the humeral head.  

PubMed

The objectives of this study were (1) to determine the most advantageous screw locations within the humeral head when plate and screw fixation is to be used and (2) to determine the effect of positioning the screw tip abutting the subchondral bone. Ten paired humeral heads were harvested with a monoplanar cut through the anatomic neck. Through use of a standardized template, 7 holes were drilled and tapped in each specimen for insertion of 6.5-mm fully threaded cancellous screws perpendicular to the plane of the cut. Paired specimens were randomized into 2 groups, one with the screw purchase in central cancellous bone and the other with the screw purchase up to the subchondral bone. Each screw was pulled out axially at a displacement rate of 10 mm/min through use of a servohydraulic testing machine. The length of thread purchase, position within the head, and screw pullout load to failure were recorded. The normalized pullout force to failure was calculated by dividing absolute pullout force to failure by length of screw purchase. Data were analyzed by means of a 2-way repeated measures analysis of variance and post hoc Student-Newman-Keuls test. The central position had a significantly higher absolute pullout force to failure than all other sites (P < .05). By virtue of the humeral head shape, the central position also had a significantly greater length of screw purchase than all other positions (P < .05). The central position had a significantly higher relative pullout force to failure than all other positions (P < .05). Subchondral bone abutment positioning improved both the absolute and the relative pullout forces to failure (P < .05). When screws and plates are used in open reduction and internal fixation of a proximal humerus fracture, a major mode of failure is loss of fixation within the humeral head. On the basis of this study, optimal screw purchase with respect to bone fixation can be achieved by including screws located in the center of the humeral head in the subchondral abutment position. To minimize screw fixation failure, the anterosuperior position should be avoided. The pattern of distribution of the relative pullout force as measured in this study is consistent with previous observational studies of patterns of trabecular density within the humeral head. PMID:11075327

Liew, A S; Johnson, J A; Patterson, S D; King, G J; Chess, D G

2000-01-01

57

Occipital condyle fractures: incidence and clinical follow-up at a level 1 trauma centre  

Microsoft Academic Search

The purpose of the study was to investigate the incidence, management, and outcomes of occipital condyle fractures at a level\\u000a 1 trauma center. Blunt trauma patients with occipital condyle fracture admitted to a level 1 trauma center over a 3-year period\\u000a were identified. Prospective clinical and functional follow-up was undertaken, including further radiographic imaging. The\\u000a incidence of occipital condyle fracture

Gregory M. Malham; Helen M. Ackland; Rachel Jones; Owen D. Williamson; Dinesh K. Varma

2009-01-01

58

An unusual metallic foreign body in the lateral tibiofemoral compartment  

Microsoft Academic Search

A child presented with pain and swelling of the knee caused by a fall on the snow. Medical imaging showed an unusual metallic foreign body in the lateral tibiofemoral compartment. Arthroscopy revealed the nature of the foreign body; a metallic piece of stone had penetrated skin and cartilage and was fastened in the cartilage of the lateral femoral condyle where

Marleen Palmers; Carl Dierickx; Patrik Peene; Eric Bijnens

2002-01-01

59

Management of Humeral and Glenoid Bone Loss in Recurrent Glenohumeral Instability  

PubMed Central

Recurrent shoulder instability and resultant glenoid and humeral head bone loss are not infrequently encountered in the population today, specifically in young, athletic patients. This review on the management of bone loss in recurrent glenohumeral instability discusses the relevant shoulder anatomy that provides stability to the shoulder joint, relevant history and physical examination findings pertinent to recurrent shoulder instability, and the proper radiological imaging choices in its workup. Operative treatments that can be used to treat both glenoid and humeral head bone loss are outlined. These include coracoid transfer procedures and allograft/autograft reconstruction at the glenoid, as well as humeral head disimpaction/humeroplasty, remplissage, humeral osseous allograft reconstruction, rotational osteotomy, partial humeral head arthroplasty, and hemiarthroplasty on the humeral side. Clinical outcomes studies reporting general results of these techniques are highlighted. PMID:25136461

Rusen, Jamie; Leiter, Jeff; Chahal, Jaskarndip; MacDonald, Peter

2014-01-01

60

Outpatient Treatment for Humeral Fractures in Five Calves  

PubMed Central

ABSTRACT Humeral fractures were treated in 5 calves using unilateral external fixation with epoxy putty fixator (type I). The surgeries were performed under sedation and analgesia, and it involved application of ultrasound-guided brachial plexus block. The surgical procedures were completed in 60 to 90 min, and each calf was returned to the farm on the same day. The fixation allowed each calf to remain with the dam and suckle without strict stall rest and was removed 11 to 62 days post-surgery. The clinical sign of diminished radial nerve function disappeared 40 days to 4 months post-surgery. These observations suggest that this repair technique represents a feasible outpatient treatment for humeral fractures in calves. PMID:25056675

YAMAGISHI, Norio; DEVKOTA, Bhuminand; TAKAHASHI, Masahiro

2014-01-01

61

Outpatient treatment for humeral fractures in five calves.  

PubMed

Humeral fractures were treated in 5 calves using unilateral external fixation with epoxy putty fixator (type I). The surgeries were performed under sedation and analgesia, and it involved application of ultrasound-guided brachial plexus block. The surgical procedures were completed in 60 to 90 min, and each calf was returned to the farm on the same day. The fixation allowed each calf to remain with the dam and suckle without strict stall rest and was removed 11 to 62 days post-surgery. The clinical sign of diminished radial nerve function disappeared 40 days to 4 months post-surgery. These observations suggest that this repair technique represents a feasible outpatient treatment for humeral fractures in calves. PMID:25056675

Yamagishi, Norio; Devkota, Bhuminand; Takahashi, Masahiro

2014-11-01

62

Comminuted periprosthetic humeral fracture after reverse shoulder prosthesis  

Microsoft Academic Search

Periprosthetic fractures represent a severe complication after joint replacement. A case of comminuted displaced humeral fracture\\u000a around the stem of a SMR reverse shoulder prosthesis is reported. The patient was a 81-year-old lady who had had a total shoulder\\u000a replacement 28 months previously. The surgical solution consisted of a partial revision of the modular implant with conservation\\u000a not only of

Renato Sommacal; Hans Rudolph Bloch; Adriana Ghidelli; Graziano Bettelli; Paolo Dalla Pria

2009-01-01

63

Condyle-fossa modifications and muscle interactions during herbst treatment, part 1. New technological methods.  

PubMed

Changes in the condyle, the glenoid fossa, and the muscles of mastication were investigated in subjects undergoing continuous orthopedic advancement of the mandible with a Herbst-block appliance. The total sample consisted of 56 subjects and included 15 nonhuman primates (in the middle mixed, early permanent, and permanent dentitions), 17 human Herbst patients in the early permanent dentition, and 24 human controls from the Burlington Growth Center. The 8 nonhuman primates in the middle mixed dentition were the focus of this study. Mandibular advancement was obtained progressively in 5 animals by adding stops to the telescopic arms of fixed functional Herbst appliances with occlusal coverage; activations of 5.0 mm, 7.0 mm, and 8.0 mm were achieved. Two primates served as controls, and the third was a sham control. Two experimental animals and the 2 controls also wore surgically implanted electromyographic electrodes in the superior and inferior heads of the lateral pterygoid muscles and in the superficial masseter and anterior digastric muscles. Changes in condylar growth direction and amount were assessed with the Björk method from measurements made on serial cephalometric tracings superimposed on metallic implants. Undecalcified sections, treated with intravenous tetracycline vital staining, were viewed with fluorescence microscopy to examine histologic changes in the condyle and the glenoid fossa. New bone formation in the fossa associated with continuous mandibular protrusion was quantified by using computerized histomorphometric analysis of decalcified histological sections and polarized light. The unique combination of permanently implanted electromyographic electrodes, tetracycline vital staining, and histomorphometry represents a significant technological advancement in methods and materials. Together, they demonstrated different muscle-bone interaction results for functional appliances than those reported in previous studies. In Part 1 of this study, we describe and discuss the techniques used in this research and give a brief overview of the findings; in Part 2 (to be published next month), we offer a more in-depth discussion of the results and the implications of our findings. PMID:12806337

Voudouris, John C; Woodside, Donald G; Altuna, Gurkan; Kuftinec, Mladen M; Angelopoulos, Gerassimos; Bourque, Paul J

2003-06-01

64

Autograft Transfer from the Ipsilateral Femoral Condyle in Depressed Tibial Plateau Fractures  

PubMed Central

Introduction : The rationale for operative treatment of depressed tibial plateau fractures is anatomic reduction, stable fixation and grafting. Grafting options include autogenous bone graft or bone substitutes. Methods : The autograft group included 18 patients with depressed tibial plateau fractures treated with autogenous bone grafting from the ipsilateral femoral condyle following open reduction and internal fixation. According to Schatzker classification, there were 9 type II, 4 type III, 2 type IV and 3 type V lesions. The average time to union and the hospital charges were compared with the bone substitute group. The latter included 17 patients who had an excellent outcome following treatment of split and/or depressed lateral plateau fractures, using a similar surgical technique but grafting with bone substitutes (allografts). Results : Excellent clinical and radiological results were detected in the autograft group after an average follow-up of 28 months (range 12-37). The average time to union in the autograft group was 14 weeks (range 12-16), while in the bone substitute group it was 18 weeks (range 16-20). The mean total cost was 1276 Euros for the autograft group and 2978 Euros for the bone substitute group. Discussion : The use of autogenous graft from the ipsilateral femoral condyle following open reduction and internal fixation of depressed tibial plateau fractures provided enough bone to maintain the height of the tibial plateau and was not associated with any donor site morbidity. Using this method, the surgical time was not significantly elongated and the rehabilitation was not affected. It also exhibited faster fracture healing without postoperative loss of reduction and it was less expensive than the use of bone substitutes. PMID:25317215

Sferopoulos, N.K

2014-01-01

65

Postarthroscopic humeral head osteonecrosis treated with reverse total shoulder arthroplasty.  

PubMed

Although postarthroscopic glenohumeral chondrolysis has become a well-known disastrous complication of arthroscopic shoulder surgery, little is known about postarthroscopic humeral head osteonecrosis. This article describes 3 patients who were referred to the authors' practice with end-stage osteonecrosis after an arthroscopic rotator cuff repair or debridement.Three patients (average age, 63.3 years) presented to the authors' practice reporting severe shoulder pain after a rotator cuff debridement or repair was performed at an outside facility. After an interval period of mild improvement, all patients experienced progressive pain and loss of shoulder range of motion at a mean of 4.8 months postoperatively. Plain radiographs and magnetic resonance imaging obtained prior to the index operation showed no evidence of osteonecrosis. Postoperatively, progressive clinical and radiographic evidence showed humeral head osteonecrosis and subsequent glenohumeral destruction with cuff tear arthropathy. The authors managed all patients with a reverse total shoulder arthroplasty due to severe glenohumeral arthrosis and massive rotator cuff tears not amendable to repair. Satisfactory results were achieved in all cases.Although many complications of arthroscopic shoulder surgery are documented, little is known about postarthroscopic humeral head osteonecrosis. Shoulder surgeons should be aware of this potential complication when performing arthroscopic rotator cuff surgery and when evaluating painful and stiff postarthroscopic shoulders. PMID:23464961

Dilisio, Matthew F; Noble, Jeffrey S; Bell, Robert H; Noel, Curtis R

2013-03-01

66

The application of the Risdon approach for mandibular condyle fractures  

PubMed Central

Background Many novel approaches to mandibular condyle fracture have been reported, but there is a relative lack of reports on the Risdon approach. In this study, the feasibility of the Risdon approach for condylar neck and subcondylar fractures of the mandible is demonstrated. Methods A review of patients with mandibular condylar neck and subcondylar fractures was performed from March 2008 to June 2012. A total of 25 patients, 19 males and 6 females, had 14 condylar neck fractures and 11 subcondylar fractures. Results All of the cases were reduced using the Risdon approach. For subcondylar fractures, reduction and fixation with plates was done under direct vision. For condylar neck fractures, reduction and fixation was done with the aid of a trochar in adults and a percutaneous threaded Kirschner wire in children. There were no malunions or nonunions revealed in follow-up care. Mild transient neuropraxia of the marginal mandibular nerve was seen in 4 patients, which was resolved within 1–2 months. Conclusions The Risdon approach is a technique for reducing the condylar neck and subcondylar fractures that is easy to perform and easy to learn. Its value in the reduction of mandibular condyle fractures should be emphasized. PMID:23829537

2013-01-01

67

Benefits of an anatomical reconstruction of the humeral head during shoulder arthroplasty: a finite element analysis  

Microsoft Academic Search

Objective. To study the influence of the shape of the prosthetic humeral head on shoulder biomechanics and then to evaluate the benefits of an anatomical reconstruction of the humeral head after shoulder arthroplasty.Design. A 3D numerical model of a healthy shoulder was reconstructed. The model included the proximal humerus, the scapula and, for stability purposes, the subscapularis, infraspinatus and supraspinatus

P. Büchler; A. Farron

2004-01-01

68

Healing of reamed glenoid bone articulating with a metal humeral hemiarthroplasty: a canine model  

Microsoft Academic Search

This study characterizes the healing response of the glenoid after spherical reaming and prosthetic humeral head replacement in a canine model of glenohumeral hemiarthroplasty. The right glenoid of twelve skeletally mature female dogs was reamed to a uniform radius of curvature, removing all cartilage down to bleeding subchondral bone. The glenoid was not resurfaced. The humeral head was replaced with

Frederick A. Matsen; John M. Clark; Robert M. Titelman; Kristi M. Gibbs; Richard S. Boorman; Daren Deffenbaugh; Donna L. Korvick; Anthony G. Norman; Susan M. Ott; Ira M. Parsons IV; John A. Sidles

2005-01-01

69

Humeres et al.: Control of Avocado Lace Bug 35 EVALUATION OF NATURAL ENEMIES AND INSECTICIDES  

E-print Network

Humeres et al.: Control of Avocado Lace Bug 35 EVALUATION OF NATURAL ENEMIES AND INSECTICIDES FOR CONTROL OF PSEUDACYSTA PERSEAE (HEMIPTERA: TINGIDAE) ON AVOCADOS IN SOUTHERN CALIFORNIA EDUARDO C. HUMERES in southern California avocado groves were eval- uated against different stages of the avocado lace bug

Hoddle, Mark S.

70

Protection of the Medial Femoral Condyle Articular Cartilage During Drilling of the Femoral Tunnel Through the Accessory Medial Portal in Anatomic Anterior Cruciate Ligament Reconstruction  

PubMed Central

Accurate positioning of the femoral tunnel in the native femoral anterior cruciate ligament (ACL) footprint requires drilling through an accessory medial portal (AMP). The AMP is located far medial and at a low level. Despite the benefits of drilling through the AMP, it is possible that the drill bit head will injure the articular cartilage of the medial femoral condyle as it slides along the guide pin to the femoral insertion of the ACL. Because more surgeons are now performing anatomic ACL reconstructions and shifting from transtibial drilling toward transportal drilling, the risk of this injury might be increasing, especially during the beginning of their learning curve. To avoid such injury, a bio-interference screw sheath is used. It is inserted through the AMP over the guide pin until it reaches near the medial wall of the lateral femoral condyle. The drill bit is inserted over the guide pin and through the bio-interference screw sheath. Using the bio-interference screw sheath not only protects the articular cartilage of the medial femoral condyle but also protects the medial meniscus, posterior cruciate ligament, and skin of the AMP from injury because of the close proximity of the drill bit head to these structures during transportal drilling. PMID:23766987

Abdelkafy, Ashraf

2012-01-01

71

Psychological stress alters microstructure of the mandibular condyle in rats.  

PubMed

Psychological stress plays an important role in the occurrence and development of temporomandibular joint disorder (TMD). The correlation between psychological factors and TMD has been clinically shown, but the influence of psychological stress on the temporomandibular joint (TMJ) structure still lacks direct evidence. Here, we used communication box to establish the rat model of psychological stress. The stress level of animals was estimated by the elevated plus maze (EPM) test and hormonal assays. The histomorphology and three-dimensional microstructure of the rat condyles were observed by hematoxylin-eosin (HE) staining and Micro-CT, respectively. Compared with control rats, the anxious state of the stressed rats was evidenced by higher plasma adrenocorticotropic hormone (ACTH) and corticosterone (CORT), as well as lower ratios of open arm entries and time and lower time spent in open arms after 1, 2, 3, 4 and 5 week(s) post-exposure to psychological stimuli. HE staining and histomorphometric data analysis showed decreased thicknesses of the central and posterior condylar cartilages in stressed rats at weeks 3, 4 and 5, with the most obvious changes in the posterior part characterized by debonding and thinned fibrous layer, thickened proliferative layer, thinned mature layer and hypertrophic layer. Moreover, Micro-CT scanning revealed local lesion of the subchondral bone in the posterior condylar cartilages of stressed rats at week 5. Our findings indicate that pathologic changes of the histomorphology and three-dimensional microstructure occur in the condyles of stressed rats, hinting us a potential link between psychological factors and the pathogenesis or progression of TMD. PMID:23313405

Li, Qiang; Zhang, Min; Chen, Yong-Jin; Zhou, Qiang; Wang, Ying-jie; Liu, Jia

2013-02-17

72

An inconvenient truth: treatment of displaced paediatric supracondylar humeral fractures.  

PubMed

The need for emergent management of displaced paediatric supracondylar humeral fractures is being questioned in the literature. Open reduction rates of up to 46% have been reported in the non-emergent management of these injuries. At our institution these fractures are managed as operative emergencies by senior personnel. To examine the ongoing need for this policy we reviewed our results. All patients managed over a five year period with Gartland type IIB or III paeditric supracondylar humeral fractures were identified and a comprehensive chart and radiographic review undertaken. The mean time from injury to fracture reduction and stabilization was 6.6 h. Consultants performed or supervised 90% of cases. Open reduction was necessary in 5% of cases. Complications included a perioperative nerve injury rate of 6% and a superficial pin site infection rate of 3%. This study suggests that, despite the challenge to trauma on-call rostering, the emergency management of these injuries is advantageous to patients in units of our size. Based on the data presented here we continue our practice of emergent management. We suggest that units of a similar size to our own would show a benefit from an analogous policy albeit an inconvenient truth. PMID:22525415

Donnelly, M; Green, C; Kelly, I P

2012-06-01

73

Limitations of B-scan ultrasound for diagnosing fractures of the mandibular condyle and ramus  

Microsoft Academic Search

The aim of this study was to analyse the applications and limitations of B-scan ultrasonography for diagnosing fractures of\\u000a the mandibular condyle and ramus. Thirty-two patients with 39 radiologically proven fractures of the mandibular condyle and\\u000a ramus were in- cluded in the study. The patients were examined with a 7.5 MHz small-part applicator. Five patients without\\u000a fractures of the facial

R. E. Friedrich; K. Plambeck; S. Bartel-Friedrich; M. Giese; R. Schmelzle

2001-01-01

74

Humeral chondrosarcoma in a Hokkaido brown bear (Ursus arctos yesoensis).  

PubMed

Humeral chondrosarcoma was found in an 18-year-old male Hokkaido brown bear (Ursus arctos yesoensis). Necropsy revealed a large firm mass under the left superficial pectoral muscle at the axillary region. The mass involved the left shoulder joint and peripheral muscles, and connected to the head of the humerus with osteolysis. Histopathologically, the mass was composed of irregularly shaped myxomatous to cartilaginous tumor lobules. The tumor cell showed moderate nuclear atypia with a relatively high mitotic index, especially in the edges of the myxomatous lobules. The tumor cells were positively immunostained with vimentin and S-100 protein. Based on these findings, the tumors were diagnosed as chondrosarcoma. Metastases were found in the left axillary lymph node, lungs, liver and kidney. PMID:22571896

Murakami, Tomoaki; Kobayashi, Yoshiyasu; Chiba, Shiori; Kurauchi, Yuki; Sakamoto, Hideyuki; Sasaki, Motoki; Matsui, Takane

2012-09-01

75

Reverse geometry shoulder replacement for proximal humeral metastases.  

PubMed

The management of skeletal metastases can be challenging for the orthopaedic surgeon. They represent a significant source of pain and disability for cancer patients, adding to the morbidity of their condition. Treatment is directed at the alleviation of symptoms and the restoration of function. Metastatic involvement of the proximal humerus can be especially debilitating, having the potential to cause severe pain and loss of function. We present a report of three such cases where reverse geometry proximal shoulder replacement was used to provide a pain free functional range of movement in patients with concomitant rotator cuff disease. In all cases, significant symptomatic relief was achieved postoperatively with preservation of upper limb function. No surgical complications were noted. It is our belief that this novel surgical strategy provides a valuable and effective option for the management of proximal humeral metastatic disease in the rotator cuff deficient patient. PMID:25245723

Kapur, R A; McCann, P A; Sarangi, P P

2014-10-01

76

External fixation for displaced 2-part proximal humeral fractures.  

PubMed

Studies have reported conflicting results regarding external fixation for displaced proximal humeral fractures. Compared with open reduction and internal fixation, external fixation for displaced proximal humeral fractures avoids dissection and soft tissue stripping and leads to higher union rates, a lower incidence of avascular necrosis, less scaring of the scapulohumeral interface, and faster rehabilitation. Some authors have reported good or excellent results and minimum complications compared with open reduction and internal fixation; however, others have reported that external fixation does not ensure acceptable reduction and fracture stability, especially in patients with osteoporosis.This article describes 18 patients with displaced 2-part fractures of the surgical neck of the humerus treated with closed reduction and external fixation using the Tension Guide Fixator (Gexfix SA, Carouge, Switzerland) external fixation system between 2010 and 2011. The patients included 14 women and 4 men with a mean age of 39 years. Mean follow-up was 18 months (range, 15-24 months). Fracture union; function using the Constant score, University of California Los Angeles score, Oxford score, and Quick Disabilities of the Arm, Shoulder and Hand shoulder score; and complications were evaluated. All patients experienced fracture union at a mean of 11 weeks (range, 9-13 weeks). The Tension Guide Fixator was removed without anesthesia at the outpatient clinic at a mean of 6 weeks (range, 4-8 weeks) with no loss of reduction or secondary displacement after removal. At 1-year follow-up, mean Constant and University of California Los Angeles scores were excellent, mean Oxford score showed satisfactory joint function, and mean Quick Disabilities of the Arm, Shoulder and Hand score showed minimal pain with no disability. PMID:23218629

Benetos, Ioannis S; Karampinas, Panayiotis K; Mavrogenis, Andreas F; Romoudis, Pavlos; Pneumaticos, Spiros G; Vlamis, John

2012-12-01

77

Occipital condyle fracture with isolated unilateral hypoglossal nerve palsy.  

PubMed

Occipital condyle fractures (OCFs) with selective involvement of the hypoglossal canal are rare. OCFs usually occur after major trauma and combine multiple fractures. We describe a 38-year-old man who presented with neck pain and a tongue deviation to the right side after a traffic accident. Severe limitations were detected during active and passive range of neck motion in all directions. A physical examination revealed a normal gag reflex and normal mobility of the palate, larynx, and shoulder girdle. He had normal taste and general sensation in his tongue. However, he presented with a tongue deviation to the right side on protrusion. A videofluoroscopic swallowing study revealed piecemeal deglutition due to decreased tongue mobility but no aspiration of food. Plain X-ray film findings were negative, but a computed tomography study with coronal reconstruction demonstrated a right OCF involving the hypoglossal canal. An electrodiagnostic study revealed evidence of right hypoglossal nerve palsy. We report a rare case of isolated hypoglossal nerve palsy caused by an OCF. PMID:25379499

Yoon, Jin Won; Lim, Oh Kyung; Park, Ki Deok; Lee, Ju Kang

2014-10-01

78

Occipital Condyle Fracture With Isolated Unilateral Hypoglossal Nerve Palsy  

PubMed Central

Occipital condyle fractures (OCFs) with selective involvement of the hypoglossal canal are rare. OCFs usually occur after major trauma and combine multiple fractures. We describe a 38-year-old man who presented with neck pain and a tongue deviation to the right side after a traffic accident. Severe limitations were detected during active and passive range of neck motion in all directions. A physical examination revealed a normal gag reflex and normal mobility of the palate, larynx, and shoulder girdle. He had normal taste and general sensation in his tongue. However, he presented with a tongue deviation to the right side on protrusion. A videofluoroscopic swallowing study revealed piecemeal deglutition due to decreased tongue mobility but no aspiration of food. Plain X-ray film findings were negative, but a computed tomography study with coronal reconstruction demonstrated a right OCF involving the hypoglossal canal. An electrodiagnostic study revealed evidence of right hypoglossal nerve palsy. We report a rare case of isolated hypoglossal nerve palsy caused by an OCF. PMID:25379499

Yoon, Jin Won; Lim, Oh Kyung; Park, Ki Deok

2014-01-01

79

Injectable Biocomposites for Bone Healing in Rabbit Femoral Condyle Defects  

PubMed Central

A novel biomimetic bone scaffold was successfully prepared in this study, which was composed of calcium sulfate hemihydrate (CSH), collagen and nano-hydroxyapatite (nHAC). CSH/nHAC was prepared and observed with scanning electron microscope and rhBMP-2 was introduced into CSH/nHAC. The released protein content from the scaffold was detected using high performance liquid chromatography at predetermined time interval. In vivo bone formation capacity was investigated by means of implanting the scaffolds with rhBMP-2 or without rhBMP-2 respectively into a critical size defect model in the femoral condyle of rabbit. The releasing character of rhBMP-2 was that an initial burst release (37.5%) was observed in the first day, followed by a sustained release and reached 100% at the end of day 20. The CSH/nHAC showed a gradual decrease in degradation with the content of nHAC increase. The results of X-rays, Micro CT and histological observation indicated that more new bone was formed in rhBMP-2 group. The results implied that this new injectable bone scaffold should be very promising for bone repair and has a great potential in bone tissue engineering. PMID:24146770

Liu, Zhengsheng; Wang, Xiumei; Cui, Fuzhai; Guo, Wenguang; Mao, Keya; Yang, Shuying

2013-01-01

80

Correlation between eminence steepness and condyle disc movements in temporomandibular joints with internal derangements on magnetic resonance imaging.  

PubMed

A steep articular eminence is reported to be a predisposing factor for the development of disc displacement. The purpose of this study was to evaluate the biomechanics of the temporomandibular joint (TMJ) in internal derangements and, additionally, to investigate whether a relationship exists between the steepness of the articular eminence and disc displacement, with (DDR) and without reduction (DDWR). The material consisted of the sagittal TMJ magnetic resonance images (MRIs) of 39 joints (26 DDR and 13 DDWR). Sagittal and coronal TMJ MRIs were obtained at maximum inter-cuspation and in the maximum mouth-opening position. The steepness of the articular eminence, disc, and condyle rotation, and condyle translation were investigated. A Student's t-test was performed and correlation coefficients calculated. The results revealed an increase in disc rotation in the DDR group and in condyle translation in the DDWR group (P < 0.01). Condyle rotation and the steepness of the articular eminence were similar in both groups. Disc rotation was positively correlated with condyle rotation and negatively correlated with condyle translation in the DDR group (P < 0.05, r = 0.44). Condyle translation was positively correlated with steepness of the articular eminence in the DDWR group (P < 0.01, r = 0.74). There was no correlation between movements of the disc-condyle assembly and the steepness of the articular eminence in the DDR group. Nevertheless, a relationship between condyle translation and the steepness of the articular eminence was found in the DDWR subjects. PMID:11668877

Gökalp, H; Türkkahraman, H; Bzeizi, N

2001-10-01

81

Multidisciplinary treatment of peripheral osteoma arising from mandibular condyle in patient presenting with facial asymmetry.  

PubMed

While osteomas often occur in the orofacial area, it is relatively rare for one to occur in the temporomandibular joint area. Here, we report a patient who underwent multidisciplinary treatment including high condylectomy for peripheral osteoma arising in the left mandibular condyle. The patient was a 46-year-old woman with the chief complaint of facial asymmetry. Cephalometric analysis revealed skeletal anterior crossbite due to anterior deviation of the mandible, with chin deviation of 10 mm to the right. A computed tomography scan revealed bone hyperplasia in the mesiodistal and inner areas of the left mandibular condyle, which exhibited outward anterior displacement. Bone scintigraphy showed a circular area of strong radioisotope accumulation with indistinct boundaries, consistent with the lesion in the left mandibular condyle. The above findings led to a diagnosis of skeletal mandibular prognathism with facial asymmetry due to peripheral osteoma originating in the left mandibular condyle. After orthodontic treatment and surgical resection of the tumor and mandibular condyle, preservation and prosthetic treatment were undertaken. A well-balanced facial appearance and good occlusion were achieved. PMID:24717929

Nojima, Kunihiko; Niizuma-Kosaka, Fumiko; Nishii, Yasushi; Sueishi, Kenji; Yamakura, Daiki; Ikumoto, Hideyuki; Ohata, Hitoshi; Inoue, Takashi

2014-01-01

82

Effect of Lateral Meniscal Allograft Sizing on Contact Mechanics of the Lateral Tibial PlateauAn Experimental Study in Human Cadaveric Knee Joints  

Microsoft Academic Search

Background: A mismatch of the original lateral meniscus and a lateral meniscus allograft by inaccurate preoperative radiographic sizing can have significant consequences on ultimate function.Hypothesis: The size of a lateral meniscal allograft affects the contact mechanics of the femoral condyle on the tibial plateau.Study Design: Controlled laboratory study.Methods: Four right and 2 left knees were tested as intact joints, after

Michael Dienst; Patrick E. Greis; Benjamin J. Ellis; Kent N. Bachus; Robert T. Burks

2007-01-01

83

Modified osteotomy for symptomatic malunion of the humeral greater tuberosity.  

PubMed

Here, we describe a modified osteotomy for malunion of the greater tuberosity that facilitates bone union and prevents symptom recurrence. The 3 most important features of this technique are: (1) osteotomizing the displaced fragment that includes the bed of the fracture, (2) placing figure-of-eight sutures by passing suture threads from inside the medullary cavity through osseous holes made in the metaphysis, and (3) pushing the distal end of the osteotomized fragment into the medullary cavity and fixing it in place. This procedure was performed on 10 patients who complained of clinical symptoms derived primarily from greater tuberosity malunion after fractures of various morphologies. Eight of these patients were available for follow-up examinations over 2 postoperative years. Constant score ratios comparing the repaired side to the uninjured side ranged from 82% to 100%. These results support the use of this modified osteotomy in achieving favorable bone union and in creating sufficient subacromial space to resolve most symptoms caused by these malunited proximal humeral fractures. PMID:24662991

Ogawa, Kiyohisa; Matsumura, Noboru; Yoshida, Atsushi

2014-12-01

84

Revision to reverse shoulder arthroplasty with retention of the humeral component  

PubMed Central

Background Revision in failed shoulder arthroplasty often requires removal of the humeral component with a significant risk of fracture and bone loss. Newer modular systems allow conversion from anatomic to reverse shoulder arthroplasty with retention of a well-fixed humeral stem. We report on a prospectively evaluated series of conversions from hemiarthroplasty to reverse shoulder arthroplasty. Methods In 14 cases of failed hemiarthroplasty due to rotator cuff deficiency and painful pseudoparalysis (in 13 women), revision to reverse shoulder arthroplasty was performed between October 2006 and 2010, with retention of the humeral component using modular systems. Mean age at the time of operation was 70 (56–80) years. Pre- and postoperative evaluation followed a standardized protocol including Constant score, range of motion, and radiographic analysis. Mean follow-up time was 2.5 (2–5.5) years. Results Mean Constant score improved from 9 (2–16) to 41 (17–74) points. Mean lengthening of the arm was 2.6 (0.9–4.7) cm without any neurological complications. One patient required revision due to infection. Interpretation Modular systems allow retainment of a well-fixed humeral stem with good outcome. There is a risk of excessive humeral lengthening. PMID:24032523

2013-01-01

85

Sagittal split ramus osteotomy for aneurysmal bone cyst of the mandibular condyle.  

PubMed

Aneurysmal bone cyst is a benign pseudocystic osseous lesion characterized by a fibrous connective tissue stroma with cellular fibrous tissue, multinucleated giant cells, and large blood-filled spaces with no endothelial lining. The entity is uncommon in facial bones, and it rarely involves the mandibular condyle. Resection of the lesion is the most accepted treatment. The present case is the 11th reported case of aneurysmal bone cyst of the mandibular condyle in the existing literature and the first where, rather than using conventional extra oral approach, sagittal split ramus osteotomy was used to excise the lesion successfully with no recurrence after 3 years of follow-up. PMID:25565239

Bhandari, Amit; Sharma, Rohit; Muralidharan, Chiyyarath Gopalan

2015-01-01

86

Functional and Radiological Evaluations of Unstable Displaced Proximal Humeral Fractures Treated with Closed Reduction and Percutaneous Pinning Fixation  

Microsoft Academic Search

Objective: The purpose of this study is to evaluate the functional and radiological outcomes of patients with unstable displaced proximal humeral fractures treated with closed reduction and percutaneous pinning (CRPP) fixation. Methods: We retrospectively reviewed 87 cases of displaced (2-, 3- or 4-part fractures according to Neer classification) proximal humeral fractures treated with CRPP fixation in our center from September

Zhe Yu; Lianhe Zheng; Yucai Wang; Yong Zhang; Xudong Zhang; Bao’an Ma

2010-01-01

87

Arthroscopic anatomic humeral head reconstruction with osteochondral allograft transplantation for large hill-sachs lesions.  

PubMed

Anatomic reconstruction of the humeral head with osteochondral allograft has been reported as a solution for large Hill-Sachs lesions with or without glenoid bone loss. However, to date, varying techniques have been used. This technical note describes an arthroscopic reconstruction technique using fresh-frozen, side- and size-matched osteochondral humeral head allograft. Allograft plugs are press fit into the defect without internal fixation and seated flush with the surrounding articular surface. This technique restores the native articular contour of the humeral head without compromising shoulder range of motion. Potential benefits of this all-arthroscopic approach include minimal trauma to the soft tissue and articular surface without the need for hardware or staged reoperation. PMID:24266001

Snir, Nimrod; Wolfson, Theodore S; Hamula, Mathew J; Gyftopoulos, Soterios; Meislin, Robert J

2013-01-01

88

Segmentation of humeral head from axial proton density weighted shoulder MR images  

NASA Astrophysics Data System (ADS)

The purpose of this study is to determine the effectiveness of segmentation of axial MR proton density (PD) images of bony humeral head. PD sequence images which are included in standard shoulder MRI protocol are used instead of T1 MR images. Bony structures were reported to be successfully segmented in the literature from T1 MR images. T1 MR images give more sharp determination of bone and soft tissue border but cannot address the pathological process which takes place in the bone. In the clinical settings PD images of shoulder are used to investigate soft tissue alterations which can cause shoulder instability and are better in demonstrating edema and the pathology but have a higher noise ratio than other modalities. Moreover the alteration of humeral head intensity in patients and soft tissues in contact with the humeral head which have the very similar intensities with bone makes the humeral head segmentation a challenging problem in PD images. However segmentation of the bony humeral head is required initially to facilitate the segmentation of the soft tissues of shoulder. In this study shoulder MRI of 33 randomly selected patients were included. Speckle reducing anisotropic diffusion (SRAD) method was used to decrease noise and then Active Contour Without Edge (ACWE) and Signed Pressure Force (SPF) models were applied on our data set. Success of these methods is determined by comparing our results with manually segmented images by an expert. Applications of these methods on PD images provide highly successful results for segmentation of bony humeral head. This is the first study to determine bone contours in PD images in literature.

Sezer, Aysun; Sezer, Hasan Basri; Albayrak, Songul

2015-01-01

89

Triangle tilt and humeral surgery: Meta-analysis of efficacy and functional outcome  

PubMed Central

AIM: To systematically review and analyze the overall impact and effectiveness of bony surgical procedures, the triangle tilt and humeral surgery in a comparative manner in permanent obstetric brachial plexus injury (OBPI) patients. METHODS: We conducted a literature search and identified original full research articles of OBPI patients treated with a secondary bony surgery, particularly addressing the limitation of shoulder abduction and functions. Further, we analyzed and compared the efficacy and the surgical outcomes of 9 humeral surgery papers with 179 patients, and 4 of our secondary bony procedure, the triangle tilt surgical papers with 86 patients. RESULTS: Seven hundred and thirty-one articles were identified, using the search term “brachial plexus” and obstetric or pediatric (246 articles) or neonatal (219 articles) or congenital (188 articles) or “birth palsy” (121 articles). Further, only a few articles were identified using the bony surgery search, osteotomy “brachial plexus” obstetric (35), “humeral osteotomy” and “brachial plexus” (17), and triangle tilt “brachial plexus” (14). Of all, 12 studies reporting pre- and post- operative or improvement in total Mallet functional score were included in this study. Among these, 9 studies reported the humeral surgery and 4 were triangle tilt surgery. We used modified total Mallet functional score in this analysis. Various studies with humeral surgery showed improvement of 1.4, 2.3, 5.0 and 5.6 total Mallet score, whereas the triangle tilt surgery showed improvement of 5.0, 5.5, 6.0 and 6.2. CONCLUSION: The triangle tilt surgery improves on what was achieved by humeral osteotomy in the management of shoulder function in OBPI patients. PMID:25621221

Nath, Rahul K; Somasundaram, Chandra

2015-01-01

90

Humeral cross-sectional shape in suspensory primates and sloths.  

PubMed

Studies on the cross-sectional geometry of long bones in African apes have documented that shape ratios derived from second moments of area about principle axes (e.g., Imax /Imin ) are often correlated with habitual locomotor behaviors. For example, humeral cross-sections tend to appear more circular in more arboreal and forelimb suspensory chimpanzees compared with terrestrial quadrupedal gorillas. These data support the hypothesis that cross-sections that are more circular in shape are adapted for multidirectional loading regimes and bending moments encountered when using acrobatic locomotor behaviors. Whether a more circular humerus reflects greater use of forelimb suspension in other primates and nonprimate mammals is unknown. In this study, cross-sections at or near midshaft of the humerus were obtained from anthropoid primates that differ in their use of forelimb suspension, as well as from two genera of suspensory sloths. Imax /Imin ratios were compared within and between groups, and correlations were made with behavioral data. In broad comparisons, observed differences in morphology follow predicted patterns. Humeri of suspensory sloths are circular. Humeri of the more suspensory hominoids tend to be more circular than those of quadrupedal taxa. Humeri of the suspensory atelines are similar to hominoids, while those of Cebus are more like nonsuspensory cercopithecoids. There is, however, considerable overlap between taxa and within finer comparisons variation between species are not in the predicted direction. Thus, although Imax /Imin ratios of the humerus are informative for characterizing generalized locomotor modes (i.e., forelimb suspensory vs. quadrupedal), additional structural information is needed for more fine-grained assessments of locomotion. PMID:23408647

Patel, Biren A; Ruff, Christopher B; Simons, Erin L R; Organ, Jason M

2013-04-01

91

Ultrasound-guided block of the brachial plexus at the humeral canal  

Microsoft Academic Search

Purpose  Conduction block of the brachial plexus block at the humeral canal, as described by Dupre, has certain clinical indications.\\u000a The aim of this preliminary study was to assess the feasibility of this technique under ultrasound guidance.\\u000a \\u000a \\u000a \\u000a Methods  After ultrasound evaluation of the brachial plexus at the humeral canal in 61 adult volunteers, we performed ultrasound-guided\\u000a blocks in another 20 adult patients.

Emmanuel Guntz; Vanessa Van den Broeck; Etienne Dereeper; Walid El Founas; Maurice Sosnowski

2009-01-01

92

Proximal humeral fractures and intramedullary nailing: Experience with a new nail system  

Microsoft Academic Search

\\u000a Abstract\\u000a \\u000a \\u000a Objectives:\\u000a   The goal of this study was to evaluate fracture healing and alignment as well as functional outcome and complication risks\\u000a after internal fixation with the intramedullary proximal humeral nail (PHN). This device shows promise for applications involving\\u000a the reconstruction of the humeral shaft and head with minimal soft tissue stripping and for providing a locked, fixed-angle\\u000a construct for

Jochen Blum; Matthias Hansen; Mathias Müller; Pol M. Rommens; Helmut Matuschka; Antonio Olmeda; Marek J. Radziejowski; Wolfgang Merbold; Stefan Nijs; Renzo Angeloni

2009-01-01

93

Separation of the Proximal Humeral Epiphysis in the Newborn: Rapid Diagnosis with Ultrasonography  

PubMed Central

Separation of the proximal humeral epiphysis (SPHE) is a well-known occurrence and may occur secondary to trauma, infection, and nonaccidental trauma. Since most newborns do not have the proximal humeral epiphysis ossified at birth, the diagnosis may be difficult to make on routine radiographs. Ultrasonography of the shoulder in the newborn is rapid, noninvasive, and nonionizing imaging techniques which can diagnose SPHE. In this report, we describe and emphasize the diagnostic utility of state-of-the-art ultrasonography for the diagnosis of SPHE. PMID:25694841

Goldfisher, Rachelle; Amodio, John

2015-01-01

94

Incipient malunion of an isolated humeral trochlea fracture treated with an elbow hemiarthroplasty: case report.  

PubMed

We report the case of a 49-year-old woman with severe elbow ankylosis 10 weeks after a trochlea fracture treated with open reduction and internal fixation. Imaging confirmed failure of open reduction and internal fixation with a displaced and severely damaged trochlea. We treated the nascent malunited trochlea and associated elbow ankylosis with a distal humeral hemiarthroplasty and circumferential elbow arthrolysis. The patient regained functional range of motion of the elbow and had minimal pain. Distal humeral hemiarthroplasty, which has been indicated for acute fractures involving the capitellum or the entire distal humerus, may also be indicated for certain isolated complex fractures of the trochlea. PMID:25542436

Lechasseur, Benoit; Laflamme, Mélissa; Leclerc, Alexandre; Bédard, Anne-Marie

2015-02-01

95

An Unusual Metallic Foreign Body inside the Knee Medial Femoral Condyle  

PubMed Central

Foreign bodies in the knee joint are uncommon, particularly those not related to surgical procedures. In this paper, we present a case of an intraosseous metallic foreign body situated in the medial femoral condyle for one year, causing pain, which was removed with complete resolution of the symptoms. PMID:25506452

Helito, Camilo Partezani; Faria, Carlos Eduardo Nunes; Bonadio, Marcelo Batista; Pecora, Jose Ricardo; Camanho, Gilberto Luis; Demange, Marco Kawamura

2014-01-01

96

Osteochondroma of the mandibular condyle: Resection and reconstruction using vertical sliding osteotomy of the mandibular ramus  

Microsoft Academic Search

Osteochondroma is one of the most common benign bone tumours, although not in the craniofacial region. More than half of these appear in the coronoid process. It can appear on the mandibular condyle, especially in its medial half, and mainly affects women aged around forty years. We present the case of a 51-year-old woman with pain of several months' duration

Sergio González-Otero; Carlos Navarro-Cuéllar; Margarita Escrig-de Teigeiro; Javier Fernández-Alba; Carlos Navarro-Vila; Servicio de Cirugía Maxilofacial

97

Association of osteopenia of the humeral head with full-thickness rotator cuff tears  

Microsoft Academic Search

Rotator cuff tendon repair may fail for various reasons. Although the role of repair techniques and of the musculotendinous unit has been studied, there is little information on the quality of the bone to which the tendon is to be repaired. Therefore, 14 cadaveric humeral heads, 7 specimens without and 7 with a full-thickness rotator cuff tendon tear, were quantitatively

Dominik C Meyer; Sandro F Fucentese; Bruno Koller; Christian Gerber

2004-01-01

98

Short communication Measuring humeral head translation using fluoroscopy: A validation study  

E-print Network

Shoulder impingement syndrome and rotator cuff tears are among the most common chronic shoulder injuries of humeral head translations and a vise that permitted rotations of the scapula about three axes. Fluoroscopy of the contour registration method to measure 2-D scapular rotations was assessed. The range for the root mean

Karduna, Andrew

99

Neurological impairment in proximal humeral fractures-dislocations undergoing shoulder replacement  

Microsoft Academic Search

The outcome of shoulder replacement for trauma has been studied in large series but not always all factors have been examined for their effects on the final results. One important element not sufficiently considered regards neurological impairment. This complication is reported in 1%–67% of shoulder dislocations and humeral neck fractures. Electromyography has an important role in revealing nerve injuries undetected

R. Padua; L. Padua; R. Bondě; A. Insola; E. Ceccarelli; A. Campi

2004-01-01

100

Resolution of a proximal humeral defect in type-1 Gaucher disease by enzyme replacement therapy  

Microsoft Academic Search

Although rarely they are a normal variant in children, significant defects in the medial aspect of the proximal humeral metaphysis occur in patients with Gaucher disease due to cortical infiltration and erosion of the periosteum by Gaucher cells. Such changes may lead to pathological fractures in Gaucher patients. These crescentic erosions resolved in a 19-year-old patient with type-1 Gaucher disease

G. M. Pastores; G. Hermann; K. Norton; R. J. Desnick

1995-01-01

101

Distal humeral epiphyseal separation in young children: an often-missed fracture-radiographic signs and ultrasound confirmatory diagnosis.  

PubMed

OBJECTIVE. Distal humeral epiphyseal separation is rare and often misdiagnosed. The purpose of this study was to summarize an experience with radiography and ultrasound of distal humeral epiphyseal separation. MATERIALS AND METHODS. The records of all children younger than 36 months with the diagnosis of distal humeral epiphyseal separation from 2006 to 2013 were identified. Medical and imaging records were reviewed for diagnosis with radiography and ultrasound, cause, treatment, and follow-up. The initial diagnosis, relation of the radius and ulna to the distal humerus, presence of other fractures, and signs of elbow effusion were evaluated. RESULTS. Sixteen patients (10 boys, six girls; mean age, 8.6 months) were evaluated for distal humeral epiphyseal separation. All patients had elbow radiographs. Fifteen (94%) patients had medial and six (38%) had posterior displacement of the radius and ulna. The diagnosis was missed on radiographs of nine (56%) patients. Ultrasound was performed for 12 patients and showed distal humeral epiphyseal separation in all. In 10 (63%) patients, one or more additional humeral fractures were found: bucket-handle fractures in five patients and condylar avulsion fracture in six patients. In the six (38%) patients younger than 1 month, distal humeral epiphyseal separation was secondary to birth trauma. In 4 of the 10 (40%) older patients, nonaccidental trauma was diagnosed. All patients underwent follow-up with a pediatric orthopedist and had full range of motion. Two patients had mild varus deformities. CONCLUSION. The diagnosis of distal humeral epiphyseal separation is often missed on radiographs. Radiologists should be aware that posteromedial displacement of the radius and ulna in young children is highly suggestive of distal humeral epiphyseal separation and that the diagnosis can be confirmed with ultrasound. PMID:25615780

Supakul, Nucharin; Hicks, Ralph A; Caltoum, Christine Beth; Karmazyn, Boaz

2015-02-01

102

Treatment of osteochondritis dissecans of the femoral condyle with autologous bone grafts and matrix-supported autologous chondrocytes  

PubMed Central

The objective of this study was to determine the clinical outcome of combined bone grafting and matrix-supported autologous chondrocyte transplantation in patients with osteochondritis dissecans of the knee. Between January 2003 and March 2005, 21 patients (mean age 29.33 years) with symptomatic osteochondritis dissecans (OCD) of the medial or lateral condyle (grade III or IV) of the knee underwent reconstruction of the joint surface by autologous bone grafts and matrix-supported autologous chondrocyte transplantation. Patients were followed up at three, six, 12 and 36 months to determine outcomes by clinical evaluation based on Lysholm score, IKDC and ICRS score. Clinical results showed a significant improvement of Lysholm-score and IKDC score. With respect to clinical assessment, 18 of 21 patients showed good or excellent results 36 months postoperatively. Our study suggests that treatment of OCD with autologous bone grafts and matrix-supported autologous chondrocytes is a possible alternative to osteochondral cylinder transfer or conventional ACT. PMID:19626325

Bruns, Juergen; Deuretzbacher, Georg; Ruether, Wolfgang; Fuerst, Martin; Niggemeyer, Oliver

2009-01-01

103

Treatment of osteochondritis dissecans of the femoral condyle with autologous bone grafts and matrix-supported autologous chondrocytes.  

PubMed

The objective of this study was to determine the clinical outcome of combined bone grafting and matrix-supported autologous chondrocyte transplantation in patients with osteochondritis dissecans of the knee. Between January 2003 and March 2005, 21 patients (mean age 29.33 years) with symptomatic osteochondritis dissecans (OCD) of the medial or lateral condyle (grade III or IV) of the knee underwent reconstruction of the joint surface by autologous bone grafts and matrix-supported autologous chondrocyte transplantation. Patients were followed up at three, six, 12 and 36 months to determine outcomes by clinical evaluation based on Lysholm score, IKDC and ICRS score. Clinical results showed a significant improvement of Lysholm-score and IKDC score. With respect to clinical assessment, 18 of 21 patients showed good or excellent results 36 months postoperatively. Our study suggests that treatment of OCD with autologous bone grafts and matrix-supported autologous chondrocytes is a possible alternative to osteochondral cylinder transfer or conventional ACT. PMID:19626325

Steinhagen, Joern; Bruns, Juergen; Deuretzbacher, Georg; Ruether, Wolfgang; Fuerst, Martin; Niggemeyer, Oliver

2010-08-01

104

Long-term results after non-plate head-preserving fixation of proximal humeral fractures  

PubMed Central

A retrospective study was conducted to evaluate displaced proximal humeral fractures treated with a non-plate head-preserving fixation and to detect factors predicting functional outcome. After a median follow-up period of 79.7 months, 105 patients with nine A-fractures, 36 B-fractures and 60 C-fractures (nine two-part-fractures, 41 three-part fractures and 55 four-part fractures) were assessed. Functional outcome was measured based on the Constant and UCLA scores. Of all patients, 70–75% had excellent or good Constant and UCLA scores. In 74% a good or satisfactory quality of initial reduction fracture was achieved. About one-fifth (21%) of the fractures showed a secondary displacement. Twenty-seven percent of the patients had signs of humeral head necrosis and 22% had implant related problems. There were significant correlations between a high final score and young age, low AO fracture severity, good quality of fracture reduction and residual osseous deformity, absence of secondary fracture displacement, implant-related complications, shoulder arthrosis and humeral head necrosis at the time of follow-up. In conclusion, the non-plate head-preserving fixation of proximal humeral fractures is an alternative treatment for displaced proximal humeral fractures. Especially in severely displaced C-fractures in older patients, non-anatomical reduction leads to a high rate of secondary displacement, residual osseous deformity and only a fair shoulder function. For these cases alternative methods such as prosthetic replacement should be chosen. PMID:19705115

Bahrs, Christian; Rolauffs, Bernd; Weise, Kuno; Zipplies, Sebastian; Dietz, Klaus; Eingartner, Christoph

2009-01-01

105

Osteochondroma (OC) of the Condyle of Left Mandible: A Rare Case  

PubMed Central

Osteochondroma (OC) is one of the most common benign condylar tumours having both chondroma and osteoma. However, this tumour is most frequently found on the metaphyses of long bones and is unusual on the skull. When it affects the mandibular condyle, the cause could be due to trauma to the tempero mandibular joint (TMJ). Here, in this report we present a rare case of osteochondroma of left condyle region in a 36-year-old man. The patient had noticed pain in the left TMJ for six months. The lesion is surgically removed and histologically evaluated which composed of chondrocytes dispersed in hyaline matrix along with a rim of calcified bone at one end. PMID:25859534

Manjunatha, Bhari Sharanesha; Kumar, Anoop N.; Alavi, Yasin A.

2015-01-01

106

Osteomyelitis of the condyle secondary to pericoronitis of a third molar: a case and literature review.  

PubMed

In this study, we report a very unusual case of a patient with osteomyelitis of the condyle secondary to pericoronitis of an impacted third molar. The patient was treated by removal of the impacted third molar, opening of the drainage, combined with systemic application of antibiotics for two weeks. This treatment option did not lead to any functional defects or facial asymmetry. The patient fully recovered and the disease did not recur. PMID:24819410

Wang, R; Cai, Y; Zhao, Y F; Zhao, J H

2014-09-01

107

Effect of alendronate on endochondral ossification in mandibular condyles of growing rats  

PubMed Central

The replacement of the calcified cartilage by bone tissue during the endochondral ossification of the mandibular condyle is dependent of the resorbing activity of osteoclats. After partial resorption, calcified cartilage septa are covered by a primary bone matrix secreted by osteoblasts. Osteoadherin (OSAD) is a small proteoglycan present in bone matrix but absent in cartilage during the endochondral ossification. The aim of this study was to analyze the effect of alendronate, a drug known to inhibit bone resorption by osteoclasts, on the endochondral ossification of the mandibular condyle of young rats, by evaluating the distribution of osteoclasts and the presence of OSAD in the bone matrix deposited. Wistar newborn rats (n=45) received daily injections of alendronate (n=27) or sterile saline solution as control (n=18) from the day of birth until the ages of 4, 14 and 30 days. At the days mentioned, the mandibular condyles were collected and processed for transmission electron microscopy analysis. Specimens were also submitted to tartrate resistant acid phosphatase (TRAP) histochemistry and ultrastructural immunodetection of OSAD. Alendronate treatment did not impede the recruitment and fusion of osteoclasts at the ossification zone during condyle growth, but they presented inactivated phenotype. The trabeculae at the ossification area consisted of cartilage matrix covered by a layer of primary bone matrix that was immunopositive to OSAD at all time points studied. Apparently, alendronate impeded the removal of calcified cartilage and maturation of bone trabeculae in the mandibular ramus, while in controls they occurred normally. These findings highlight for giving attention to the potential side-effects of bisphosphonates administered to young patients once it may represent a risk of disturbing maxillofacial development. PMID:22688305

Bradaschia-Correa, V.; Barrence, F.A.C.; Ferreira, L.B.; Massa, L.F.; Arana-Chavez, V.E.

2012-01-01

108

Adult Stem Cell Driven Genesis of Human-Shaped Articular Condyle  

Microsoft Academic Search

Uniform design of synovial articulations across mammalian species is challenged by their common susceptibility to joint degeneration. The present study was designed to investigate the possibility of creating human-shaped articular condyles by rat bone marrow-derived mesenchymal stem cells (MSCs) encapsulated in a biocompatible poly(ethylene glycol)-based hydrogel. Rat MSCs were harvested, expanded in culture, and treated with either chondrogenic or osteogenic

Adel Alhadlaq; Jennifer H. Elisseeff; Liu Hong; Christopher G. Williams; Arnold I. Caplan; Blanka Sharma; Ross A. Kopher; Sara Tomkoria; Donald P. Lennon; Aurora Lopez; Jeremy J. Mao

2004-01-01

109

Trabecular bone structure in the mandibular condyles of gouging and nongouging platyrrhine primates.  

PubMed

The relationship between mandibular form and biomechanical function is a topic of significant interest to morphologists and paleontologists alike. Several previous studies have examined the morphology of the mandible in gouging and nongouging primates as a means of understanding the anatomical correlates of this feeding behavior. The goal of the current study was to quantify the trabecular bone structure of the mandibular condyle of gouging and nongouging primates to assess the functional morphology of the jaw in these animals. High-resolution computed tomography scan data were collected from the mandibles of five adult common marmosets (Callithrix jacchus), saddle-back tamarins (Saguinus fuscicollis), and squirrel monkeys (Saimiri sciureus), respectively, and various three-dimensional morphometric parameters were measured from the condylar trabecular bone. No significant differences were found among the taxa for most trabecular bone structural features. Importantly, no mechanically significant parameters, such as bone volume fraction and degree of anisotropy, were found to vary significantly between gouging and nongouging primates. The lack of significant differences in mechanically relevant structural parameters among these three platyrrhine taxa may suggest that gouging as a habitual dietary behavior does not involve significantly higher loads on the mandibular condyle than other masticatory behaviors. Alternatively, the similarities in trabecular architecture across these three taxa may indicate that trabecular bone is relatively unimportant mechanically in the condyle of these primates and therefore is functionally uninformative. PMID:19918988

Ryan, Timothy M; Colbert, Matthew; Ketcham, Richard A; Vinyard, Christopher J

2010-04-01

110

Current Concepts in the Mandibular Condyle Fracture Management Part I: Overview of Condylar Fracture  

PubMed Central

The incidence of condylar fractures is high, but the management of fractures of the mandibular condyle continues to be controversial. Historically, maxillomandibular fixation, external fixation, and surgical splints with internal fixation systems were the techniques commonly used in the treatment of the fractured mandible. Condylar fractures can be extracapsular or intracapsular, undisplaced, deviated, displaced, or dislocated. Treatment depends on the age of the patient, the co-existence of other mandibular or maxillary fractures, whether the condylar fracture is unilateral or bilateral, the level and displacement of the fracture, the state of dentition and dental occlusion, and the surgeonnds on the age of the patient, the co-existence of othefrom which it is difficult to recover aesthetically and functionally;an appropriate treatment is required to reconstruct the shape and achieve the function ofthe uninjured status. To do this, accurate diagnosis, appropriate reduction and rigid fixation, and complication prevention are required. In particular, as mandibular condyle fracture may cause long-term complications such as malocclusion, particularly open bite, reduced posterior facial height, and facial asymmetry in addition to chronic pain and mobility limitation, great caution should be taken. Accordingly, the authors review a general overview of condyle fracture. PMID:22872830

Yang, Jung-Dug; Chung, Ho-Yun; Cho, Byung-Chae

2012-01-01

111

Novel use of ultrasound in the ED: ultrasound-guided hematoma block of a proximal humeral fracture.  

PubMed

Proximal humeral fractures are a common injury after falls, particularly in the elderly population. An ultrasound-guided hematoma block is a novel technique for analgesia in cases when standard intravenous analgesia is not efficacious. We present a case in which ultrasound-guided hematoma block was the ideal method for adjunctive pain control in a patient with a comminuted humeral head fracture. PMID:25082594

Lovallo, Emily; Mantuani, Daniel; Nagdev, Arun

2015-01-01

112

Throwing in the Middle and Upper Paleolithic: inferences from an analysis of humeral retroversion.  

PubMed

When in evolutionary history did long-range projectile weapons become an important component of hunting toolkits? The archeological evidence for the development of projectile weaponry is complex and generally indirect, and has led to different conclusions about the origin and spread of this technology. Lithic evidence from the Middle Stone Age (MSA) has led some researchers to suggest that true long- range projectile weaponry developed in Africa perhaps as early as 80,000 years ago, and was part of the subsistence toolkit carried by modern humans who expanded out of Africa after 50,000 years ago. Alternatively, temporal patterns in the morphology of pointed lithics has led others to posit an independent, convergent origin of projectile weaponry in Africa, the Near East, and Europe during the interval between 50,000-40,000 years ago. By either scenario, projectile weapons would not have been a component of the hunting arsenal of Neandertals, but may have been in use by European early modern humans and thus, projectile technology may have entered into the competitive dynamics that existed between these two groups. The origins of projectile weapons can be addressed, in part, through analyses of the skeletal remains of the prehistoric humans who made and used them. Habitual behavior patterns--including those related to the production and use of technology--can be imprinted on the skeleton through both genetic and epigenetic pathways. Recent studies in the field of sports medicine indicate that individuals who engage in habitual throwing have increased humeral retroversion angles in their throwing arms and a greater degree of bilateral asymmetry in retroversion angles than do non-throwers. This contribution investigates humeral torsion through analysis of the retroversion angle in samples of Eurasian Neandertals, European early modern humans of the middle and late Upper Paleolithic, and comparative samples of recent humans. This analysis was conducted under the assumption that if throwing-based projectile weaponry was used by early modern Europeans but not Neandertals, Upper Paleolithic samples should be similar to recent human groups engaged in habitual throwing in the degree of humeral retroversion in the dominant limb and in bilateral asymmetry in this feature. Neandertals on the other hand, would not be expected to show marked asymmetry in humeral retroversion. Consistent with other studies, Neandertals exhibit increased retroversion angles (decreased humeral torsion or a more posteriorly oriented humeral head) relative to most modern human samples, although this appears more likely related to body form and overall activity levels than to habitual throwing. Although Neandertals with bilaterally preserved humeri sufficient for measurement are rare (consisting of only two males and one female), levels of bilateral asymmetry in humeral retroversion are low, suggesting a lack of regular throwing. While patterning across fossil and comparative samples in levels of humeral retroversion was not clear cut, males of both the middle and late Upper Paleolithic demonstrate a high level of bilateral asymmetry, comparable to or in excess of that seen in samples of throwing athletes. This may indicate habitual use of throwing-based projectile weaponry by middle Upper Paleolithic times. Small sample sizes and relatively great variance in the fossil samples makes these results, however, suggestive rather than conclusive. PMID:19004469

Rhodes, Jill A; Churchill, Steven E

2009-01-01

113

Results of non-union of humerus treated with retrograde humeral nail.  

PubMed

Treating non-union of humerus fracture is a surgical challenge with variable outcome. We report series of 51 adult patients of aseptic non-union of humerus from 1998 to 2010 treated retrograde humeral nail. The mean age of patient was 54 years with 33 females and 18 males. The mean duration of non-union was 8 months. In 48 out of 51 cases (94 %), union was achieved at mean duration of 10.1 months. Thirty-two out of 51 patients needed bone grafting. Three patients had post-operative radial nerve neuropraxia which fully recovered. At last visit, mean Constant score for shoulder was 83 and mean Mayo score for elbow 78. Our series with this implant shows excellent union rates for extra articular humeral non-unions in adults. PMID:25427782

Bhatt, Hinesh; Varghese, Bobin; Phillips, Hannah; Rambani, Rohit; Halder, Subhash

2014-11-27

114

Glenohumeral internal rotation deficit in the asymptomatic professional pitcher and its relationship to humeral retroversion.  

PubMed

The purpose of this study was to determine if glenohumeral internal rotation deficits (GIRD) exist in an asymptomatic population of professional pitchers, and to assess whether these changes are primarily a bony or soft tissue adaptation. Twenty three, active, asymptomatic professional (Major League Baseball) pitchers volunteered for the study. Clinical measures of glenohumeral ranges of motion, laxity, GIRD, as well as radiographic measures of humeral retroversion were taken by two independent orthopaedic surgeons. Data comparing side to side differences in range of motion, laxity, and humeral retroversion were analyzed for statistical significance using a paired t-test for continuous data and a Chi-squared test for ordinal data, with a significance set at 0.05. Evaluations of statistical correlations between different measurement parameters were accomplished using a Pearson product moment correlation. We hypothesized GIRD will be positively correlated with humeral retroversion (HR) in the pitching arm. All clinical and radiographic measures were made in the field, at spring training, by physicians of both private and institutional based sports medicine practices. For the entire group, significant differences were exhibited for HR, external rotation at 90° and internal rotation at 90°, for dominant vs. non-dominant arms. GIRD of greater than 25° was noted in 10/23 of pitchers. In this group, HR was significantly increased and correlated to GIRD. No such increase or correlation was noted for the non-GIRD group. GIRD is a common finding in asymptomatic professional pitchers, and is related to humeral retroversion. Thus internal rotation deficits should not be used as the sole screening tool to diagnose the disabled throwing shoulder. Key pointsGIRD is relatively common in asymptomatic baseball pitchers (35-43%).Large ranges (-45 to 5°) and a large standard deviation (±16°) were noted suggesting that GIRD is quite variable in this population.GIRD is a variable measure in the asymptomatic population, and therefore should not be used as sole proof for the disabled throwing shoulder. PMID:24150137

Tokish, John M; Curtin, Michael S; Kim, Young-Kyu; Hawkins, Richard J; Torry, Michael R

2008-01-01

115

Interlocking nailing of humeral shaft fractures: the Oxford experience 1991 to 1994  

Microsoft Academic Search

Forty-three patients with fractures of the humeral shaft were treated by locked intermedullary nailing, using the Russell-Taylor nailing system. Overall there were few technical problems with nail insertion. Additional fracture comminution occurred in five patients but affected stability in only one case. Twenty-six nails were inserted into 22 patients with pathological fractures. The objective of fracture stabilization and pain relief

T. E. J. Hems; T. P. S. Bhullar

1996-01-01

116

Humeral epiphyseal shape in the felidae: the influence of phylogeny, allometry, and locomotion.  

PubMed

Bone morphology of the cats (Mammalia: Felidae) is influenced by many factors, including locomotor mode, body size, hunting methods, prey size and phylogeny. Here, we investigate the shape of the proximal and distal humeral epiphyses in extant species of the felids, based on two-dimensional landmark configurations. Geometric morphometric techniques were used to describe shape differences in the context of phylogeny, allometry and locomotion. The influence of these factors on epiphyseal shape was assessed using Principal Component Analysis, Linear Discriminant functions and multivariate regression. Phylogenetic Generalised Least Squares was used to examine the association between size or locomotion and humeral epiphyseal shape, after taking a phylogenetic error term into account. Results show marked differences in epiphyseal shape between felid lineages, with a relatively large phylogenetic influence. Additionally, the adaptive influences of size and locomotion are demonstrated, and their influence is independent of phylogeny in most, but not all, cases. Several features of epiphyseal shape are common to the largest terrestrial felids, including a relative reduction in the surface area of the humeral head and increased robusticity of structures that provide attachment for joint-stabilising muscles, including the medial epicondyle and the greater and lesser tubercles. This increased robusticity is a functional response to the increased loading forces placed on the joints due to large body mass. PMID:23065662

Walmsley, Anthony; Elton, Sarah; Louys, Julien; Bishop, Laura C; Meloro, Carlo

2012-12-01

117

Scapula and humeral movement patterns and their relationship with pain: A preliminary investigation  

PubMed Central

Purpose Altered movement patterns may contribute to this shoulder pain following stroke. The purpose of this study was to examine scapular and humeral movement patterns in people with hemiparetic shoulder pain (HSP), and to explore the relationships between pain and these movement patterns. Methods Kinematic data from nine participants with HSP and twelve matched controls were collected as they performed scapular plane shoulder elevation. Correlation analyses were used to examine relationships between participants’ ratings of pain and kinematic data. Results The HSP group had decreased humeral external rotation compared to the control group. Despite a trend toward decreased scapular upward rotation, there was considerable variation in scapular upward rotation movement patterns across the participants with HSP. Scapular tilt was not different between groups. There was an inverse relationship between pain and scapular upward rotation, indicating that those with more pain had less scapular upward rotation. Conclusions People with HSP demonstrated scapular and humeral movement patterns that differed from controls, where some of the altered movement patterns were related to reported pain levels. Rehabilitation management of people with HSP may be improved by careful assessment of scapulohumeral movement patterns and treatments aimed at normalizing these patterns. PMID:22866060

Hardwick, Dustin D.; Lang, Catherine E.

2011-01-01

118

Treatment of Femoral Shaft Fracture with an Interlocking Humeral Nail in Older Children and Adolescents  

PubMed Central

Purpose Rigid interlocking nailing for femoral shaft fracture is ideal for use in adolescents in terms of stability of the fracture and convenience for the patient. However, numerous authors have reported that rigid interlocking nailing has some limitations in this age group due to the risk of complications. We evaluated the results of intramedullary nailing for femoral shaft fractures with an interlocking humeral nail in older children and adolescents. Materials and Methods We retrospectively reviewed records of patients treated with an interlocking humeral nail. Radiographs were examined for proximal femoral change and evidence of osteonecrosis. Outcomes were assessed by major or minor complications that occurred after operative treatment. Results Twenty-four femoral shaft fractures in 23 patients were enrolled. The mean age at the time of operation was 12 years and 8 months and the mean follow-up period was 21 months. Bony union was achieved in all patients without any complications related to the procedure such as infection, nonunion, malalignment and limb length discrepancy. All fractures were clinically and radiographically united within an average eight weeks. No patients developed avascular necrosis of the femoral head and coxa valga. Conclusion Intramedullary nailing through the greater trochanter using a rigid interlocking humeral nail is effective and safe for the treatment of femoral shaft fractures in older children and adolescents. PMID:22318831

Park, Hoon

2012-01-01

119

Arthroscopic treatment of a large lateral femoral notch in acute anterior cruciate ligament tear.  

PubMed

A 24-year-old professional soccer player suffered an acute anterior cruciate ligament tear associated with a radiologically evident impression fracture of the lateral femoral condyle, the so-called "lateral femoral notch sign". Following MRI validation of the injury with detection of an additional lateral meniscus tear, arthroscopy was carried out 3 days after the injury. Due to the extended impression of about 5 mm, arthroscopically assisted closed reduction of the depression fracture was performed. A 3.2 mm tunnel was drilled at the lateral femoral condyle in a supero-inferior direction using an ACL tibial guide and the depressed area could be restored using an elevator. The resulting subchondral bone defect in the femoral condyle was filled with freeze-dried human cancellous bone allograft. As a one-stage procedure ACL reconstruction was carried out using a hamstring tendon technique. At 1-year follow up the patient has returned to full sporting function, including playing soccer with a radiographically reduced lateral femoral notch sign. PMID:18060552

Tauber, Mark; Fox, Michael; Koller, Heiko; Klampfer, Helmut; Resch, Herbert

2008-11-01

120

Intra-protocol repeatability and inter-protocol agreement for the analysis of scapulo-humeral coordination.  

PubMed

Multi-center clinical trials incorporating shoulder kinematics are currently uncommon. The absence of repeatability and limits of agreement (LoA) studies between different centers employing different motion analysis protocols has led to a lack dataset compatibility. Therefore, the aim of this work was to determine the repeatability and LoA between two shoulder kinematic protocols. The first one uses a scapula tracker (ST), the International Society of Biomechanics anatomical frames and an optoelectronic measurement system, and the second uses a spine tracker, the INAIL Shoulder and Elbow Outpatient protocol (ISEO) and an inertial and magnetic measurement system. First within-protocol repeatability for each approach was assessed on a group of 23 healthy subjects and compared with the literature. Then, the between-protocol agreement was evaluated. The within-protocol repeatability was similar for the ST ([Formula: see text] = 2.35°, [Formula: see text] = 0.97°, SEM = 2.5°) and ISEO ([Formula: see text] = 2.24°, [Formula: see text] = 0.97°, SEM = 2.3°) protocols and comparable with data from published literature. The between-protocol agreement analysis showed comparable scapula medio-lateral rotation measurements for up to 120° of flexion-extension and up to 100° of scapula plane ab-adduction. Scapula protraction-retraction measurements were in agreement for a smaller range of humeral elevation. The results of this study suggest comparable repeatability for the ST and ISEO protocols and between-protocol agreement for two scapula rotations. Different thresholds for repeatability and LoA may be adapted to suit different clinical hypotheses. PMID:24136689

Parel, I; Cutti, A G; Kraszewski, A; Verni, G; Hillstrom, H; Kontaxis, A

2014-03-01

121

Assessment of Condyle and Glenoid Fossa Morphology Using CBCT in South-East Asians  

PubMed Central

Introduction Proper imaging allows practitioners to evaluate an asymptomatic tempormandibular joint (TMJ) for potential degenerative changes prior to surgical and orthodontic treatment. The recently developed cone-beam computed tomography (CBCT) allows measurement of TMJ bony structures with high accuracy. A study was undertaken to determine the morphology, and its variations, of the mandibular condyle and glenoid fossa among Malay and Chinese Malaysians. Methods CBCT was used to assess 200 joints in 100 subjects (mean age, 30.5 years). i-CAT CBCT software and The Mimics 16.0 software were employed to measure the volume, metrical size, position of each condyle sample and the thickness of the roof of the glenoid fossa (RGF). Results No significant gender differences were noted in thickness of the RGF and condylar length; however condylar volume, width, height and the joint spaces were significantly greater among males. With regards to comparison of both TMJs, the means of condylar volume, width and length of the right TMJ were significantly higher, while the means of the left condylar height and thickness of RGF were higher. When comparing the condylar measurements and the thickness of RGF between the two ethnic groups, we found no significant difference for all measurements with exception of condylar height, which is higher among Chinese. Conclusion The similarity in measurements for Malays and Chinese may be due to their common origin. This information can be clinically useful in establishing the diagnostic criteria for condylar volume, metrical size, and position in the Malaysian East Asians population. PMID:25803868

Al-koshab, May; Nambiar, Phrabhakaran; John, Jacob

2015-01-01

122

Reliability of computational measurement of the condyles on digital panoramic radiographs  

PubMed Central

Objective The aim of this study was to evaluate the reliability of a computational method for assessing three condylar measurements on digital panoramic radiographs: condylar height, area and perimeter. Methods A computer calculation of the area, the perimeter and the height of 34 condyles was determined on digital panoramic radiographs taken from 17 patients. The test–retest precision of measurements calculation was estimated using an intraclass correlation coefficient (ICC) and Dahlberg's formula at 2 week intervals on the same radiograph to assess intraobserver precision and on two radiographs (RX1 and RX2) to assess the radiographic procedure precision. Changes between measurements on RX1 and RX2 were estimated using paired t-tests to detect systematic errors. Results Precision of all indices was very high when measurements were made on the same radiograph, thus confirming good reliability for the present computational measuring method. The precision was lower when two different radiographs were compared but was still within an acceptable range of tolerance. There were no statistically significant changes in condylar area, perimeter or height values between RX1 and RX2. Conclusions This study has demonstrated that (1) the height of the condyle can be rapidly and reliably assessed using a specific computer system directly on digital panoramic radiographs; (2) although less reliable, area and perimeter can also be acceptably evaluated; and (3) this method has the potential for being routinely used to monitor changes in clinical follow-up as well as for research purposes. PMID:21960403

Momjian, A; Courvoisier, D; Kiliaridis, S; Scolozzi, P

2011-01-01

123

Current Concepts in the Mandibular Condyle Fracture Management Part II: Open Reduction Versus Closed Reduction  

PubMed Central

In the treatment of mandibular condyle fracture, conservative treatment using closed reduction or surgical treatment using open reduction can be used. Management of mandibular condylar fractures remains a source of ongoing controversy in oral and maxillofacial trauma. For each type of condylar fracture,the treatment method must be chosen taking into consideration the presence of teeth, fracture height, patient'sadaptation, patient's masticatory system, disturbance of occlusal function, and deviation of the mandible. In the past, closed reduction with concomitant active physical therapy conducted after intermaxillary fixation during the recovery period had been mainly used, but in recent years, open treatment of condylar fractures with rigid internal fixation has become more common. The objective of this review was to evaluate the main variables that determine the choice of an open or closed method for treatment of condylar fractures, identifying their indications, advantages, and disadvantages, and to appraise the current evidence regarding the effectiveness of interventions that are used in the management of fractures of the mandibular condyle. PMID:22872831

Yang, Jung-Dug; Chung, Ho-Yun; Cho, Byung-Chae

2012-01-01

124

The effect of humeral torsion on rotational range of motion in the shoulder and throwing performance  

PubMed Central

Several recent studies have found that throwing athletes typically have lower humeral torsion (retroversion) and a greater range of external rotation at the shoulder than non-athletes. How these two parameters are related is debated. This study uses data from a sample of both throwers and non-throwers to test a new model that predicts torsion values from a range of motion data. The model proposes a series of predicted regressions which can help provide new insight into the factors affecting rotational range of motion at the shoulder. Humeral torsion angles were measured from computed tomography scans collected from 25 male subjects. These values are compared to predicted torsion values for the same subjects calculated from both kinematic and goniometric range-of-motion data. Results show that humeral torsion is negatively correlated (goniometric: r = ?0.409, P = 0.047; kinematic: r = ?0.442, P = 0.035) with external rotational range of motion and positively correlated (goniometric: r = 0.741, P < 0.001; kinematic: r = 0.559, P = 0.006) with internal rotational range of motion. The predicted torsion values are highly correlated (goniometric: r = 0.815, P < 0.001; kinematic: r = 0.617, P = 0.006) with actual torsion values. Deviations in the data away from predicted equations highlight significant differences between high torsion and low torsion individuals that may have significant functional consequences. The method described here may be useful for non-invasively assessing the degree of torsion in studies of the evolution and biomechanics of the shoulder and arm, and for testing hypotheses about the etiology of repetitive stress injuries among athletes and others who throw frequently. PMID:22257273

Roach, Neil Thomas; Lieberman, Daniel E; Gill, Thomas J; Palmer, William E; Gill, Thomas J

2012-01-01

125

Surgical versus conservative treatment for displaced proximal humeral fractures in elderly patients: a meta-analysis  

PubMed Central

Purpose: Treatment strategies for complex displaced proximal humeral fractures (DPHF) in elderly patients remain controversial. This meta-analysis was performed to compare the benefits and risks of surgical or conservative methods for these patients. Methods: Pubmed, Cochrane library and EMBASE were systematically searched for randomized controlled trials (RCTs) from their establishment to June 2013. Researches on surgical/conservative treatment for complex displaced proximal humeral fractures in elderly patients were selected. Methodological quality of included studies was evaluated by the Physiotherapy Evidence Database (PEDro) scale. Outcome measurements were Constant score, DASH (disabilities of the arm, shoulder and hand), postoperative complications and quality of life (QoL). The meta-analysis was performed with software Stata 12.0. Results: Six RCTs with 272 patients were included and analyzed. Fix studies with a PEDro score of 6 or more were of high quality. The differences in QoL (WMD 0.43, 95% CI (0.12, 0.74)) and postoperative complications (RR 2.06, 95% CI (1.45, 2.93)) were statistically significant between operative and conservative treatment. There was no statistically significant difference in Constant score (WMD 0.06, 95% CI (-0.20, 0.31)) and DASH (WMD 0.33, 95% CI (-0.70, 0.04)). Conclusion: Despite the small improvement of QoL, surgical treatments did not significantly improve the functional outcome including Constant score and DASH. Instead, surgical treatment for displaced proximal humeral fractures in elderly patients led to higher incidence of postoperative complications. PMID:25663957

Fu, Tao; Xia, Chengyan; Li, Zonghuan; Wu, Hua

2014-01-01

126

Humeral external rotation handling by using the Bobath concept approach affects trunk extensor muscles electromyography in children with cerebral palsy.  

PubMed

This study aimed to investigate the electromyographic activity of cervical and trunk extensors muscles in children with cerebral palsy during two handlings according to the Bobath concept. A crossover trial involving 40 spastic diplegic children was conducted. Electromyography (EMG) was used to measure muscular activity at sitting position (SP), during shoulder internal rotation (IR) and shoulder external rotation (ER) handlings, which were performed using the elbow joint as key point of control. Muscle recordings were performed at the fourth cervical (C4) and at the tenth thoracic (T10) vertebral levels. The Gross Motor Function Classification System (GMFCS) was used to assess whether muscle activity would vary according to different levels of severity. Humeral ER handling induced an increase on EMG signal of trunk extensor muscles at the C4 (P=0.007) and T10 (P<0.001) vertebral levels. No significant effects were observed between SP and humeral IR handling at C4 level; However at T10 region, humeral IR handling induced an increase of EMG signal (P=0.019). Humeral ER resulted in an increase of EMG signal at both levels, suggesting increase of extensor muscle activation. Furthermore, the humeral ER handling caused different responses on EMG signal at T10 vertebra level, according to the GMFCS classification (P=0.017). In summary, an increase of EMG signal was observed during ER handling in both evaluated levels, suggesting an increase of muscle activation. These results indicate that humeral ER handling can be used for diplegic CP children rehabilitation to facilitate cervical and trunk extensor muscles activity in a GMFCS level-dependent manner. PMID:25462474

Grazziotin Dos Santos, C; Pagnussat, Aline S; Simon, A S; Py, Rodrigo; Pinho, Alexandre Severo do; Wagner, Mário B

2014-10-20

127

Humeral Rotational Osteotomy for Shoulder Deformity in Obstetric Brachial Plexus Palsy: Which Direction Should I Rotate?  

PubMed Central

Shoulder internal rotation contracture is the most common deformity affecting the shoulder in patients with Obstetric Brachial Plexus Palsy. With progression of the deformity, the glenohumeral joint starts to subluxate and then dislocates. This is accompanied with bony changes of both the humerus and the glenoid. Two opposite direction humeral osteotomies have been proposed for this condition (internal rotation osteotomy (IRO) and external rotation osteotomy (ERO)). This fact of different direction osteotomies has not adequately been explained in the literature. Most orthopedic surgeons may not be able to fully differentiate between these two osteotomies regarding the indications, outcomes and effects on the joint. This review explains these differences in details. PMID:24987487

Abdelgawad, Amr A; Pirela-Cruz, Miguel A

2014-01-01

128

Humeral rotational osteotomy for shoulder deformity in obstetric brachial plexus palsy: which direction should I rotate?  

PubMed

Shoulder internal rotation contracture is the most common deformity affecting the shoulder in patients with Obstetric Brachial Plexus Palsy. With progression of the deformity, the glenohumeral joint starts to subluxate and then dislocates. This is accompanied with bony changes of both the humerus and the glenoid. Two opposite direction humeral osteotomies have been proposed for this condition (internal rotation osteotomy (IRO) and external rotation osteotomy (ERO)). This fact of different direction osteotomies has not adequately been explained in the literature. Most orthopedic surgeons may not be able to fully differentiate between these two osteotomies regarding the indications, outcomes and effects on the joint. This review explains these differences in details. PMID:24987487

Abdelgawad, Amr A; Pirela-Cruz, Miguel A

2014-01-01

129

Use of a proximal humeral plate for a paediatric peri-prosthetic femoral fracture  

PubMed Central

In this case an 18-year-old female with cerebral palsy sustained a peri-prosthetic femoral fracture adjacent to a blade plate previously inserted for a femoral varus osteotomy. The injury was treated using a long proximal humeral locking plate. The existing blade plate was removed. The fracture was reduced and held, and a 10-hole PHILOS™ plate applied with near anatomical reduction. There were no post-operative complications. Radiographic union was confirmed at 11 months. To our knowledge, this is the first reported use of a PHILOS™ plate in the management of a femoral peri-prosthetic fracture and successfully demonstrated a straightforward method for revision fixation. PMID:24986984

Shaw, C.R.; Badhesha, J.; Ayana, G.; Abu-Rajab, R.

2014-01-01

130

The isolated medial humeral epicondyle fracture treated nonoperatively: does fracture displacement change over time?  

PubMed

This study explores the change in the position of the fragment in isolated, displaced, medial humeral epicondyle fractures in children. In this series, 34 patients (mean age 11.0 years) were treated nonoperatively by cast immobilization with no attempt at closed fracture reduction. A statistically significant association was found between the position of the fracture fragment at the time of initial fracture compared with 3 weeks after fracture (P=0.015). Twenty-six of 34 patients (76.5%) showed spontaneous improvement in fragment position. These findings support the practice of treating significantly displaced medial epicondyle fractures nonoperatively. PMID:25643146

Lim, Kevin Boon Leong; Woo, Chin Yee; Chong, Xue Ling; Ul-Alam, Shehab; Allen, John C

2015-05-01

131

Shockwave Therapy in the Management of Complex Regional Pain Syndrome in Medial Femoral Condyle of the Knee  

Microsoft Academic Search

The aim of this prospective study was to assess the efficacy of shockwave (SW) therapy in the management of complex regional pain syndrome (CRPS). In this study, 30 patients (pts) who were affected by CRPS of the medial femoral condyle and unresponsive to previous standard physiotherapeutic and pharmacological treatment underwent 3 SW sessions at 72-h intervals, each consisting of 4000

Angela Notarnicola; Lorenzo Moretti; Silvio Tafuri; Antonio Panella; Marco Filipponi; Alessio Casalino; Michele Panella; Biagio Moretti

2010-01-01

132

Bone Marrow Stimulation of the Medial Femoral Condyle Produces Inferior Cartilage and Bone Repair Compared to the Trochlea in a  

E-print Network

-CT analysis showed that repaired TR defects regained normal un-operated values of bone volume fraction, trabecular thickness, and trabecular number, whereas in MFC defects the repaired bone architecture appearedBone Marrow Stimulation of the Medial Femoral Condyle Produces Inferior Cartilage and Bone Repair

Buschmann, Michael

133

Intraosseous ganglion cyst of the humeral head in a competitive flat water paddler: case report  

PubMed Central

Objective To present the diagnostic and clinical features of an intraosseous ganglion cyst of the humeral head of a female flat water canoe athlete. Clinical Features An 18-year old female flat water canoeist complaining of right shoulder pain following a strenuous paddling training camp. Intervention and outcome A trial of passive care was conducted, including soft tissue therapy, spinal manipulative therapy, acupuncture, and rehabilitation. The patient seemed to be responding with treatment, but pain would always resume with paddling. A diagnostic ultrasound displayed mild thickening and effusion in the subacromial/subdeltoid bursae. Continued passive care was not able to resolve the symptoms and she underwent an MRI which revealed an intraosseus ganglion cyst subjacent to the lesser tuberosity and floor of the intertubercular groove. A subsequent MRA was ordered to assess the labrum, which was intact, but the cyst had progressed in size. She was referred to an orthopedic surgeon who performed surgery. Conclusion An IOG cyst within the humeral head is a rare, potentially painful condition that can mimic other pathologies including impingement and labral tear. It is important to be aware of the clinical features to obtain a prompt diagnosis and appropriate treatment of this condition. PMID:22131566

Muir, Brad; Kissel, Jaclyn A.; Yedon, Dominique Forand

2011-01-01

134

Treatment of Mandibular Condyle Fractures Using a Modified Transparotid Approach via the Parotid Mini-Incision: Experience with 31 Cases  

PubMed Central

Surgery for mandibular condyle fractures must allow direct vision of the fracture, reduce surgical trauma and achieve reduction and fixation while avoiding facial nerve injury. This prospective study was conducted to introduce a new surgical approach for open reduction and internal fixation of mandibular condyle fractures using a modified transparotid approach via the parotid mini-incision, and surgical outcomes were evaluated. The modified transparotid approach via the parotid mini-incision was applied and rigid internal fixation using a small titanium plate was carried out for 36 mandibular condyle fractures in 31 cases. Postoperative follow-up of patients ranged from 3 to 26 months; in the first 3 months after surgery, outcomes for all patients were analyzed by evaluating the degree of mouth opening, occlusal relationship, facial nerve function and results of imaging studies. The occlusal relationships were excellent in all patients and none had symptoms of intraoperative ipsilateral facial nerve injury. The mean degree of mouth opening was 4.0 (maximum 4.8 cm, minimum 3.0 cm). No mandibular deviations were noted in any patient during mouth opening. CT showed complete anatomical reduction of the mandibular condyle fracture in all patients. The modified transparotid approach via the smaller, easily concealed parotid mini-incision is minimally invasive and achieves anatomical reduction and rigid internal fixation with a simplified procedure that directly exposes the fracture site. Study results showed that this procedure is safe and feasible for treating mandibular condyle fracture, and offers a short operative path, protection of the facial nerve and satisfactory aesthetic outcomes. PMID:24386221

Shi, Jun; Yuan, Hao; Xu, Bing

2013-01-01

135

Endoscope-assisted intraoral excision of osteochondroma of the mandibular condyle.  

PubMed

Osteochondroma (OC) is one of the most common bony lesions of the skeleton. It is rare in the maxillofacial region and reported infrequently in the literature. This lesion is considered the most common of benign tumors of the temporomandibular joint. It is usually associated with the coronoid, followed by the condyloid process. OC can affect any bone formed from cartilage and can arise spontaneously or as a result of osseous trauma. It usually protrudes from the surface of bone and is covered with cartilage. Most condylar OCs present as progressive limitation of mandibular movements, facial asymmetry, malocclusion, pain, and deviation in mouth opening. Extraoral approaches to the OCs, which are usually located on the medial pole of the condyle, provide ease of accessibility, although there is an inherent likelihood of damage to the facial nerve and scarring. The use of a transoral endoscope-assisted conservative approach for the removal of OCs produces the desired favorable esthetic and functional results. PMID:25636973

Singh, Divya; Gadre, Pushkar; Gadre, Kiran; Setiya, Sneha

2015-04-01

136

Developed Design for Humeral Head Replacement Using 3D Surface Maping  

NASA Astrophysics Data System (ADS)

Assessment of dimensional and geometrical data on the humeral head replacement (HHR) objects is essential for solving the relevant designing problems in the physics of reverse engineering (RE). In this work, 2D-assessment for human humerus was performed using the computed tomography (CT) technique within the RE plan, after which the 2D images of humeral objects were converted into 3D images. The conversion was successful and indicated a clear difference in the 2D and 3D estimates of sizes and geometry of the humerus. The authors have analyzed and confirmed experimentally the statistical information on the relevant anatomical objects. The results of finite-element simulation of the compressive stresses affecting the geometry of 3D surface mapping were analyzed using SolidWorks software. For developing the biomechanical design of an HHR object suitable biomaterials were selected, and different metal-based biomaterials are discussed as applied at various loads. New methodology is presented for the size estimation of humeral head - both anatomical and artificial - in 3D-shape. A detailed interpretation is given for the results of CT D-measurements. Izm?ru un ?eometrisko datu nov?rt?jums, kas attiecas uz pleca kaula galvi?as nomai?as (PKGN) objektiem, nepieciešams, lai risin?tu virkni revers?v?s inženierijas (RI) probl?mu. Šaj? darb? cilv?ka pleca kaula galvi?as divdimensiju nov?rt?jums tika veikts ar datortomogr?fijas pal?dz?bu (RI) ietvaros, un p?c tam objekta divdimensiju att?lojums tika p?rveidots tr?sdimensiju. P?rveidojums bija sekm?gs, par?dot pleca kaula galvi?as izm?ru un ?eometrijas atš?ir?bas starp 2D un 3D nov?rt?jumiem. Autori izanaliz?ja un eksperiment?li apstiprin?ja statistisko inform?ciju p?c dot? veida anatomiskiem objektiem. Saspiešanas sasprindzin?jumi, kuri ietekm? tr?sdimensiju virsmas att?lojuma ?eometriju, tika analiz?ti ar gala-elementu simul?cijas metodi, lietojot programmu SolidWorks. Biomehaniskajam PKGN dizainam tika atlas?ti piem?roti materi?li. Apspriesta daž?du biomateri?lu ar met?lisko pamatu reakcija uz main?g?m slodz?m. Tiek pied?v?ta pleca kaula galvi?as - k? anatomiskas, t? m?ksl?gas - tr?s dimensijas m?r?šanas metodolo?ijas. Dota datortomogr?fisko prec?zo m?r?jumu rezult?tu detaliz?ta interpret?cija.

Springis, G.; Rudzitis, J.; Avisane, A.; Leitans, A.

2014-12-01

137

Intermittent Pre-Excitation-Syndrome in Facio-Scapulo-Humeral Muscular Dystrophy  

PubMed Central

Pre-excitation-syndrome has not been reported as a phenotypic feature of facio-scapulo-humeral muscular dystrophy (FSH-MD). In a 39-year-old male with FSH-MD due to a reduced tandem repeat size in the D4Z4-locus on chromosome 4q35, cardiac involvement, manifesting as an incomplete right bundle-branch-block, tall T-waves in V 3-5, ST-elevation in V 2-4, and mild thickening of the left ventricular myocardium, was first recognised 10 years earlier. Follow-up at age 39 years revealed mild myocardial thickening, two intra-ventricular aberrant bands, and, surprisingly, intermittent pre-excitation on a routine electrocardiography. Cardiac involvement in FSH-MD may manifest as hypertrophic cardiomyopathy or various arrhythmias, of which one may be pre-excitation-syndrome. PMID:25278989

Stöllberger, Claudia; Gatterer, Edmund; Jakubiczka, Sibylle

2014-01-01

138

A complicated, metastatic, humeral air sac cystadenocarcinoma in a timneh African grey parrot (Psittacus erithacus timneh).  

PubMed

A 9-year-old male timneh African grey parrot (Psittacus erithacus timneh) was presented because of inability to fly and suspected trauma. The owner also had observed dyspnea, with tail bobbing and open-beak breathing. On clinical examination, a hard, painful mass was palpable in the left proximal humerus and axillary area. Radiographs revealed a radiodense soft tissue mass of the left humerus with no bony involvement, multifocal opacities in lung and air sacs, and an enlarged spleen. An asymmetric, vascularized cyst was detected in the mass by ultrasound examination. Results of biopsy of the mass revealed multifocal cysts composed of unilayer isoprismatic cells laying in vascularized connective tissue. Because of the severity of clinical signs and the poor clinical condition, the bird was euthanatized. On postmortem examination, the findings were air sac cystadenocarcinoma involving the humeral air sac with metastases in the spleen and kidneys, atherosclerosis, pneumoconiosis, and mycotic granulomatous pneumonia and airsacculitis with isolation of Aspergillus niger. PMID:23772455

Azmanis, Panagiotis; Stenkat, Julia; Hübel, Jens; Böhme, Julia; Krautwald-Junghanns, Maria Elisabeth; Schmidt, Volker

2013-03-01

139

Humeral cortical thickness in female Bantu - its relationship to the incidence of femoral neck fracture  

SciTech Connect

Measurements of the humeral cortical thickness demonstrate that generalised osteoporosis in female Bantu commences in the fifth decade and gradually increases until, in the ninth decade, all subjects are osteoporotic. The combined cortical thickness (CCT) of the humerus in young adults is very similar to that found previously in a white London population and the loss of cortex with age is very similar. It is concluded that the known low incidence of femoral neck fracture in Bantu is not due to a lower incidence of generalised osteoporosis but to environmental factors. The chief environmental factor postulated is the greater amount of physical work performed by the Bantu. A more careful mode of walking is suggested as a subsidiary cause.

Bloom, R.A.; Pogrund, H.

1982-03-01

140

A coincidental variation of the axillary artery: the brachioradial artery and the aberrant posterior humeral circumflex artery passing under the tendon of the latissimus dorsi muscle  

PubMed Central

A case of anomalous terminal branching of the axillary artery was encountered and described in a left upper limb of a male cadaver. A series of 214 upper limbs of Caucasian race was dissected. A variant artery, stemming from the very end of the axillary artery followed a superficial course distally. It passed the cubital fossa, ran on the lateral side of the forearm as usual radial artery, crossed ventrally to the palm and terminated in the deep palmar arch. This vessel is a case of the brachioradial artery (incorrectly termed as the “radial artery with high origin”). Moreover, it was associated with another variation, concerning the aberrant posterior humeral circumflex artery passing under the tendon of the latissimus dorsi muscle. The anatomical knowledge of the axillary region is essential for radiodiagnostic, surgical and traumatologic procedures. The superficially located artery brings an elevated danger of heavy bleeding in all unexpected situations, its variant branching can cause problems in radial catheterization procedures and the anomalously coursing other arterial variant poses an elevated danger in surgical procedures concerning the surgical neck of humerus. PMID:25428677

Konarik, Marek; Kachlik, David; Baca, Vaclav

2014-01-01

141

Complications and Outcomes of Minimally Invasive Percutaneous Plating for Proximal Humeral Fractures  

PubMed Central

Background The minimally invasive plate osteosynthesis (MIPO) technique using periarticular locking plates may be a good option for the repair of displaced proximal humeral fractures. However, axillary nerve complications related to this technique may be underestimated. The purpose of this study is to evaluate the outcomes of the minimally invasive plating, focusing on the complications. Methods The records of 21 consecutive patients treated for proximal humerus fractures using the MIPO technique with locking plates were retrospectively reviewed. These patients were treated between March 2009 and March 2011 with a minimum one-year follow-up. The clinical function, complications, and radiological bony union were evaluated. Results All of the patients, with one exception, showed at least 90 degrees of flexion and abduction at the shoulder joint six months postoperatively. The average Constant scores at three months, six months, and one year follow-ups were 74.0 (range, 62 to 90), 79.4 (range, 64 to 91), and 82.7 (range, 66 to 92), respectively. All of the patients achieved bony union within the average of 3.2 months (range, 2 to 6 months). There was one case of delayed union, one case of intra-articular screw penetration, and one case of axillary nerve paresis (incomplete injury), which did not completely recover during the one year of follow-up. Conclusions The MIPO technique using periarticular locking plates is a useful option for the treatment of selected cases of displaced proximal humeral fractures. However, nerve complications such as axillary nerve paresis should be considered along with implant-related complications when choosing patients for minimally invasive plating. PMID:24900894

Jeong, Seong Yup

2014-01-01

142

Mesenchymal Stem Cells and Platelet Gel Improve Bone Deposition within CAD-CAM Custom-Made Ceramic HA Scaffolds for Condyle Substitution  

PubMed Central

Purpose. This study evaluated the efficacy of a regenerative approach using mesenchymal stem cells (MSCs) and CAD-CAM customized pure and porous hydroxyapatite (HA) scaffolds to replace the temporomandibular joint (TMJ) condyle. Methods. Pure HA scaffolds with a 70% total porosity volume were prototyped using CAD-CAM technology to replace the two temporomandibular condyles (left and right) of the same animal. MSCs were derived from the aspirated iliac crest bone marrow, and platelets were obtained from the venous blood of the sheep. Custom-made surgical guides were created by direct metal laser sintering and were used to export the virtual planning of the bone cut lines into the surgical environment. Sheep were sacrificed 4 months postoperatively. The HA scaffolds were explanted, histological specimens were prepared, and histomorphometric analysis was performed. Results. Analysis of the porosity reduction for apposition of newly formed bone showed a statistically significant difference in bone formation between condyles loaded with MSC and condyles without (P < 0.05). The bone ingrowth (BI) relative values of split-mouth comparison (right versus left side) showed a significant difference between condyles with and without MSCs (P < 0.05). Analysis of the test and control sides in the same animal using a split-mouth study design was performed; the condyle with MSCs showed greater bone formation. Conclusion. The split-mouth design confirmed an increment of bone regeneration into the HA scaffold of up to 797% upon application of MSCs. PMID:24073409

Ciocca, L.; Donati, D.; Ragazzini, S.; Dozza, B.; Rossi, F.; Fantini, M.; Spadari, A.; Romagnoli, N.; Landi, E.; Tampieri, A.; Piattelli, A.; Iezzi, G.; Scotti, R.

2013-01-01

143

Finite element analysis of three patterns of internal fixation of fractures of the mandibular condyle.  

PubMed

The most stable pattern of internal fixation for fractures of the mandibular condyle is a matter for ongoing discussion. In this study we investigated the stability of three commonly used patterns of plate fixation, and constructed finite element models of a simulated mandibular condylar fracture. The completed models were heterogeneous in the distribution of bony material properties, contained about 1.2 million elements, and incorporated simulated jaw-adducting musculature. Models were run assuming linear elasticity and isotropic material properties for bone. This model was considerably larger and more complex than previous finite element models that have been used to analyse the biomechanical behaviour of differing plating techniques. The use of two parallel 2.0 titanium miniplates gave a more stable configuration with lower mean element stresses and displacements over the use of a single miniplate. In addition, a parallel orientation of two miniplates resulted in lower stresses and displacements than did the use of two miniplates in an offset pattern. The use of two parallel titanium plates resulted in a superior biomechanical result as defined by mean element stresses and relative movement between the fractured fragments in these finite element models. PMID:22981343

Aquilina, Peter; Chamoli, Uphar; Parr, William C H; Clausen, Philip D; Wroe, Stephen

2013-06-01

144

OSTEOCHONDRAL INTERFACE REGENERATION OF THE RABBIT MANDIBULAR CONDYLE WITH BIOACTIVE SIGNAL GRADIENTS  

PubMed Central

PURPOSE Tissue engineering solutions focused on the temporomandibular joint (TMJ) have expanded in number and variety over the past decade to address the treatment of TMJ disorders. The existing literature on approaches for healing small defects in the TMJ condylar cartilage and subchondral bone, however, is sparse. The purpose of this study was thus to evaluate the performance of a novel gradient-based scaffolding approach to regenerate osteochondral defects in the rabbit mandibular condyle. MATERIALS AND METHODS Miniature bioactive plugs for regeneration of small mandibular condylar defects in New Zealand White rabbits were fabricated. The plugs were constructed from poly(D,L-lactic-co-glycolic acid) (PLGA) microspheres with a gradient transition between cartilage-promoting and bone-promoting growth factors. RESULTS At six weeks of healing, results suggested that the implants provided support for the neo-synthesized tissue as evidenced by histology and 9.4T magnetic resonance imaging. CONCLUSION The inclusion of bioactive factors in a gradient-based scaffolding design is a promising new treatment strategy for focal defect repair in the TMJ. PMID:21470747

Dormer, Nathan H.; Busaidy, Kamal; Berkland, Cory J.; Detamore, Michael S.

2011-01-01

145

Use of intramedullary fibular strut graft: a novel adjunct to plating in the treatment of osteoporotic humeral shaft nonunion  

Microsoft Academic Search

Humeral shaft fractures respond well to conservative treatment and unite without much problem. Since it is uncommon, there\\u000a is not much discussion regarding the management of nonunion in the literature, and hence this is a challenge to the treating\\u000a orthopaedic surgeon. Osteoporosis of the fractured bone and stiffness of the surrounding joints compounds the situation further.\\u000a The Ilizarov fixator, locking

S. Vidyadhara; K. Vamsi; Sharath K. Rao; James J. Gnanadoss; S. Pandian

2009-01-01

146

Humeral internal rotation osteotomy for the treatment of Erb-Duchenne-type obstetric palsy: clinical and radiographic results  

PubMed Central

OBJECTIVE: To evaluate the functional and radiographic results in patients undergoing shoulder anterior soft tissue stretching in association with open reduction and internal rotation osteotomy to centralize the humeral head as a treatment for Erb-Duchenne obstetric palsy sequelae. METHOD: A total of 35 patients underwent this surgical treatment, and the mean follow-up was 4.6 years. The Mallet scale was applied before and after the surgical procedure. A total of 20 patients underwent computed tomography to assess the glenoid version and humeral head subluxation. RESULTS: Functional improvement was achieved, as evidenced by an increase in the Mallet scale score from 12.14 to 16.46 (p<0.001). The correction of retroversion was achieved once the glenoid version ranged from -21.4 to -12 degrees (p<0.001). The humeral head subluxation improved from 6.5 to 35.2% (p<0.001). Patients older than 6 years of age did not achieve glenohumeral joint improvement with respect to dysplastic abnormalities. CONCLUSION: Internal rotation osteotomy in association with the stretching of anterior soft tissues of the shoulder in patients under the age of 7 years provided improvements in the function, retroversion, and subluxation of the glenohumeral joint. PMID:23917655

Assunçăo, Jorge Henrique; Neto, Arnaldo Amado Ferreira; Benegas, Eduardo; Neto, Raul Bolliger; Prada, Flávia Santis; Malavolta, Eduardo Angeli; Gracitelli, Mauro Emilio Conforto; Camanho, Gilberto Luis

2013-01-01

147

[Muscle efficiency in total shoulder prosthesis implantation: dependence on position of the humeral head and rotator cuff function].  

PubMed

Modern shoulder prostheses permit an anatomic reconstruction of the joint, although the biomechanical advantages are not proven. The goal of this study was to investigate the relationship between position of the humeral head and function of the shoulder prosthesis (muscle efficiency). Shoulder elevation-motion and rotator cuff defects were simulated in vitro in a robot-assisted shoulder simulator. The EPOCA Custom Offset shoulder prosthesis (Argomedical AG, Cham, CH) was implanted in seven normal shoulders (77 +/- 20 kg, 55 +/- 14 years). Active elevation was simulated by hydraulic cylinders, and scapulothoratic motion by a specially programmed industrial robot. Muscle efficiency (elevation-angle/muscle-force of the deltoid muscle) was measured in anatomic (ANA), medialised (MED) and lateralised (LAT) positions of the humeral head, with or without rotator cuff muscle deficiency. Medialisation increased efficiency by 0.03 +/- 0.04 deg/N (p = 0.022), lateralisation decreased it by 0.04 +/- 0.06 deg/N (p = 0.009). Supraspinatus muscle deficiency increased the deltoid force required to elevate the arm, and thus decreased efficiency (ANA p = 0.091, MED p = 0.018, LAT p = 0.028). The data confirm that the position of the humeral head affects the mechanics of total shoulder arthroplasty. Medialisation increases efficiency of the deltoid muscle and may prove useful in compensating isolated supraspinatus muscle deficiency. Lateralisation, in contrast, leads to an unfavorable situation. PMID:11593981

Klages, A; Hurschler, C; Wülker, N; Windhagen, H

2001-09-01

148

Microcomputed tomographic analysis of human condyles in unilateral condylar hyperplasia: increased cortical porosity and trabecular bone volume fraction with reduced mineralisation.  

PubMed

Unilateral condylar hyperplasia or hyperactivity is a disorder of growth that affects the mandible, and our aim was to visualise the 3-dimensional bony microstructure of resected mandibular condyles of affected patients. We prospectively studied 17 patients with a clinical presentation of progressive mandibular asymmetry and an abnormal single-photon emission computed tomographic (SPECT) scan. All patients were treated by condylectomy to arrest progression. The resected condyles were scanned with micro-CT (18 ?m resolution). Rectangular volumes of interest were selected in 4 quadrants (lateromedial and superoinferior) of the trabecular bone of each condyle. Variables of bone architecture (volume fraction, trabecular number, thickness, and separation, degree of mineralisation, and degree of structural anisotrophy) were calculated with routine morphometric software. Eight of the 17 resected condyles showed clear destruction of the subchondral layer of cortical bone. There was a significant superoinferior gradient for all trabecular variables. Mean (SD) bone volume fraction (25.1 (6) %), trabecular number (1.69 (0.26) mm(-1)), trabecular thickness (0.17 (0.03) mm), and degree of mineralisation (695.39 (39.83) mg HA/cm(3)) were higher in the superior region. Trabecular separation (0.6 (0.16) mm) and structural anisotropy (1.84 (0.28)) were higher in the inferior region. The micro-CT analysis showed increased cortical porosity in many of the condyles studied. It also showed a higher bone volume fraction, greater trabecular thickness and trabecular separation, greater trabecular number, and less mineralisation in the condyles of the 17 patients compared with the known architecture of unaffected mandibular condyles. PMID:25219775

Karssemakers, L H E; Nolte, J W; Tuinzing, D B; Langenbach, G E J; Raijmakers, P G; Becking, A G

2014-12-01

149

Treatment of the humeral shaft fractures - minimally invasive osteosynthesis with bridge plate versus conservative treatment with functional brace: study protocol for a randomised controlled trial  

PubMed Central

Background Humeral shaft fractures account for 1 to 3% of all fractures in adults and for 20% of all humeral fractures. Non-operative treatment is still the standard treatment of isolated humeral shaft fractures, although this method can present unsatisfactory results. Surgical treatment is reserved for specific conditions. Modern concepts of internal fixation of long bone shaft fractures advocate relative stabilisation techniques with no harm to fracture zone. Recently described, minimally invasive bridge plate osteosynthesis has been shown to be a secure technique with good results for treating humeral shaft fractures. There is no good quality evidence advocating which method is more effective. This randomised controlled trial will be performed to investigate the effectiveness of surgical treatment of humeral shaft fractures with bridge plating in comparison with conservative treatment with functional brace. Methods/Design This randomised clinical trial aims to include 110 patients with humeral shaft fractures who will be allocated after randomisation to one of the two groups: bridge plate or functional brace. Surgical treatment will be performed according to technique described by Livani and Belangero using a narrow DCP plate. Non-operative management will consist of a functional brace for 6 weeks or until fracture consolidation. All patients will be included in the same rehabilitation program and will be followed up for 1 year after intervention. The primary outcome will be the DASH score after 6 months of intervention. As secondary outcomes, we will assess SF-36 questionnaire, treatment complications, Constant score, pain (Visual Analogue Scale) and radiographs. Discussion According to current evidence shown in a recent systematic review, this study is one of the first randomised controlled trials designed to compare two methods to treat humeral shaft fractures (functional brace and bridge plate surgery). Trial registration Current Controlled Trials: ISRCTN24835397 PMID:23924198

2013-01-01

150

Fractures of the occipital condyle clinical spectrum and course in eight patients  

PubMed Central

Introduction: Occipital condyle fractures (OCFs) are considered to be rare injuries. OCFs are now diagnosed more often because of the widespread use of computed tomography. Our aim is to report the incidence, treatment and long term outcome of 8 patients with OCFs. Materials and Methods: All patients presenting with multiple trauma from 1993 to 2006 were analyzed retrospectively. Characteristics and course of the treatment were evaluated. Follow-up was performed after 11,7 years (range 5,9 to 19,3 years). Results: Nine cases of OCF in 8 patients were identified. All injuries resulted from high velocity trauma. The average scores on the ISS Scale were 39,6 (24-75) and 7,3 (3-15) on the GCS. According to Anderson's classification, 5 cases of Type III and 4 cases of Type I fractures were identified. According to Tuli's classification, 5 cases of Type IIA and 4 cases of Type I were found. Indications for immobilization with the halo-vest were type III injuries according to Anderson's classification or Tuli's type IIA injuries, respectively. Patients with Tuli's type I injuries were treated with a Philadelphia collar for 6 weeks. In one patient with initial complete tetraplegia and one with incomplete neurological deficits the final follow-up neurologic examination showed no neurological impairment at all (Frankel-grade A to E, respectively B to E). At follow-up, 3 patients were asymptomatic. Four patients suffered from mild pain when turning their head, pain medication was necessary in one case only. Discussion: OCF's are virtually undetectable using conventional radiography. In cases of high velocity, cranio-cervical trauma or impaired consciousness, high resolution CT-scans of the craniocervical junction must be performed. We suggest immobilization using a halo device for type III injuries according to Anderson's classification or Tuli's type IIa injuries, respectively. Patients with Tuli's type I injuries should be treated with a Philadelphia collar. PMID:24744561

Krüger, Antonio; Oberkircher, Ludwig; Frangen, Thomas; Ruchholtz, Steffen; Kühne, Christian; Junge, Andreas

2013-01-01

151

Rotation osteotomy of the humerus for Erb's palsy in children with humeral head deformity.  

PubMed

The most common secondary deformity in older children with Erb's birth palsy is internal rotation contracture of the shoulder. The results of external rotation osteotomy of the humerus in a selected series of children with shoulder internal rotation contracture are reported. Fifteen consecutive patients with a mean age of 6.5 years were included. In all children the internal rotation contracture was associated with loss of the normal sphericity of the humeral head as assessed by preoperative magnetic resonance imaging. The humerus osteotomy was carried out just below the insertion of the deltoid muscle, and fixation was done with stainless steel plate and screws. The results were assessed with a modified Mallet score. Before surgery 12 children had a score of 2 and 3 children had a score of 3. At final follow-up evaluation (range, 1-5 years; average, 3 years), all 15 children had improved shoulder function and obtained a modified Mallet score of 4. An extra bonus of the osteotomy procedure was slight improvement of shoulder abduction and elbow extension. All children could dress, wash, perform self-cleaning, and feed themselves better and no longer needed help with these activities. This osteotomy for selected children is simple and safe and has a high satisfaction rate functionally and aesthetically. PMID:12015723

Al-Qattan, Mohammad M

2002-05-01

152

Changes in position of the temporomandibular joint disc and condyle after disc repositioning appliance therapy: a functional examination and magnetic resonance imaging study.  

PubMed

Disc-repositioning splints are routinely used in the treatment of anteriorly displaced discs. The rationale of these appliances is to direct the mandibular condyle anteriorly in the glenoid fossa and to recapture the disc onto the condyle. The stability of disc recapture depends on reestablishment of the occlusion and the adaptive capabilities of the temporomandibular joint. It could therefore be suggested that treatment success is potentially higher in the active growth period. In this case report, partial disc recapture was observed on magnetic resonance images after application of a maxillary disc-repositioning appliance. Orthodontic treatment was applied for the retention of disc recapture. PMID:11037001

Gökalp, H; Türkkahraman, H

2000-10-01

153

IS 3D-CT REFORMATION USING FREE SOFTWARE APPLICABLE TO DIAGNOSIS OF BONE CHANGES IN MANDIBULAR CONDYLES?  

PubMed Central

Objectives: This study evaluated the agreement of computed tomography (CT) imaging using 3D reformations (3DR) with shaded surface display (SSD) and maximum intensity projection (MIP) in the diagnosis of bone changes in mandibular condyles of patients with rheumatoid arthritis (RA), and compared findings with multiplanar reformation (MPR) images, used as the criterion standard. Material and Methods: Axial CT images of 44 temporomandibular joints (TMJs) of 22 patients with RA were used. Images were recorded in DICOM format and assessed using free software (ImageJ). Each sample had its 3DR-SSD and 3DR-MIP results compared in pairs with the MPR results. Results: Slight agreement (k = 0.0374) was found in almost all comparisons. The level of agreement showed that 3DR-SSD and 3DR-MIP yielded a number of false-negative results that was statistically significant when compared with MPR. Conclusions: 3DR-SSD or 3DR-MIP should only be used as adjuvant techniques to MPR in the diagnosis of bone changes in mandibular condyles. PMID:19466245

de Oliveira, Marília Gerhardt; Morais, Luciano Engelmann; Silva, Daniela Nascimento; de Oliveira, Helena Willhelm; Heitz, Cláiton; Gaiăo, Lęonilson

2009-01-01

154

Recovery of mouth-opening after closed treatment of a fracture of the mandibular condyle: a longitudinal study.  

PubMed

The aim of this retrospective study was to assess recovery of mouth opening after closed treatment of fractures of the mandibular condyle, and analyse which characteristics might influence recovery. We measured mouth opening in 142 patients (mean (SD) age 30 (14) years, 96 of whom were male) during follow-up at 3, 6, 13, 26, and 52 weeks after the injury. Fractures were assessed on radiographs. Data were analysed using a multilevel analysis. Half the fractures were of the low condylar neck (n=71). Thirty-seven patients had bilateral condylar fractures, 29 had dislocated fractures, and in 80 the fracture was displaced. One or more additional mandibular fractures were present in 68. During follow-up mean (SD) mouth opening increased to: 33.6 (9.6) at 3 weeks, 40.1 (10.0) at 6 weeks, 45.1 (9.6) at 13 weeks, 49.8 (9.5) at 26 weeks, and 52.6 (7.5) at 52 weeks. Older age, female sex, displaced fracture, bilateral fractures, additional mandibular fractures, and the interaction between follow-up time and additional mandibular fractures, were predictors of a less favourable recovery of mouth opening. Clinicians can use the results of this study to predict recovery of mouth opening after closed treatment of fractures of the mandibular condyle at first consultation. PMID:25480010

Niezen, E T; Stuive, I; Post, W J; Bos, R R M; Dijkstra, P U

2015-02-01

155

Indications for computed tomography (CT-) diagnostics in proximal humeral fractures: a comparative study of plain radiography and computed tomography  

PubMed Central

Background Precise indications for computed tomography (CT) in proximal humeral fractures are not established. The purpose of this study was a comparison of conventional radiographic views with different CT reconstructions with 2 D and 3 D imaging to establish indications for additional CT diagnostics depending on the fractured parts. Methods In a prospective diagnostic study in two level 1 trauma centers, 44 patients with proximal humeral fractures were diagnosed with conventional X-rays (22 AP + axillary views, 22 AP + scapular Y-views) and CT (multi-planar reconstruction (MPR) and maximum intensity projection (MIP)) with 2 D and 3 D imaging. 3 observers assessed the technical image quality, the assessment of the relevant anatomical structures (2-sample-t-test) and the percentage of the osseous overlap of the proximal humerus (Welch-test) using a scoring system. The quality of the different diagnostic methods was assessed according to the number of fractured parts (Bonferroni-Holm adjustment). Results There was significantly more overlap of the fractured region on the scapular Y-views (mean 71.5%, range 45–90%) than on axillary views (mean 56.2%, range 10.5–100%). CT-diagnostics allowed a significantly better assessment of the relevant structures than conventional diagnostics (p < 0.05) independently of the fracture severity (two-, three-, and four-part fractures). Conclusion Conventional X-rays with AP view and a high-quality axillary view are useful for primary diagnostics of the fracture and often but not always show a clear presentation of the relevant bony structures such as both tuberosities, the glenoid and humeral head. CT with thin slices technology and additional 3 D imaging provides always a clear presentation of the fractured region. Clinically, a CT should be performed – independently of the number of fractured parts – when the proximal humerus and the shoulder joint are not presented with sufficient X-ray-quality to establish a treatment plan. PMID:19341472

Bahrs, Christian; Rolauffs, Bernd; Südkamp, Norbert P; Schmal, Hagen; Eingartner, Christoph; Dietz, Klaus; Pereira, Philippe L; Weise, Kuno; Lingenfelter, Erich; Helwig, Peter

2009-01-01

156

Additive fiber-cerclages in proximal humeral fractures stabilized by locking plates  

PubMed Central

Background and purpose The effect of additive fiber-cerclages in proximal humeral fractures stabilized by locking plates on fracture stabilization and rotator cuff function is unclear. Here it was assessed in a human cadaver study. Methods 24 paired human shoulder specimens were harvested from median 77-year-old (range 66–85) female donors. An unstable 3-part fracture model with an intact rotator cuff was developed. 1 specimen of each pair received an additive fiber-cerclage of the rotator cuff after plate fixation, and the other one received a plate fixation without an additive fiber-cerclage. Force-controlled hydraulic cylinders were used to simulate physiological rotator cuff tension, while a robot-assisted shoulder simulator performed 4 relevant cases of load: (1) axial loading at 0°, (2) glenohumeral abduction at 60°, (3) internal rotation at 0° abduction, and (4) external rotation at 0° abduction, and imitated hanging arm weight during loading without affecting joint kinematics. A 3-dimensional real-time interfragmentary motion analysis was done in fracture gaps between the greater tuberosity and the head, as well as subcapital. The capacity of the rotator cuff to strain was analyzed with an optical system. Results Interfragmentary motion was similar between the groups with and without fiber-cerclages, in both fracture gaps and in any of the cases of load. Cerclages did not impair the capacity of the rotator cuff to strain. Interpretation Provided that unstable 3-part fractures are reduced and stabilized anatomically by a locking plate, additive fiber-cerclages do not reduce interfragmentary motion. Additive fiber-cerclages may be necessary in locking plate osteosyntheses of multiple-fractured greater tuberosities or lesser tuberosity fractures that cannot be fixed sufficiently by the plate. PMID:19562564

Hurschler, Christof; Rech, Louise; Vosshenrich, Rolf; Lill, Helmut

2009-01-01

157

HUMeral Shaft Fractures: MEasuring Recovery after Operative versus Non-operative Treatment (HUMMER): a multicenter comparative observational study  

PubMed Central

Background Fractures of the humeral shaft are associated with a profound temporary (and in the elderly sometimes even permanent) impairment of independence and quality of life. These fractures can be treated operatively or non-operatively, but the optimal tailored treatment is an unresolved problem. As no high-quality comparative randomized or observational studies are available, a recent Cochrane review concluded there is no evidence of sufficient scientific quality available to inform the decision to operate or not. Since randomized controlled trials for this injury have shown feasibility issues, this study is designed to provide the best achievable evidence to answer this unresolved problem. The primary aim of this study is to evaluate functional recovery after operative versus non-operative treatment in adult patients who sustained a humeral shaft fracture. Secondary aims include the effect of treatment on pain, complications, generic health-related quality of life, time to resumption of activities of daily living and work, and cost-effectiveness. The main hypothesis is that operative treatment will result in faster recovery. Methods/design The design of the study will be a multicenter prospective observational study of 400 patients who have sustained a humeral shaft fracture, AO type 12A or 12B. Treatment decision (i.e., operative or non-operative) will be left to the discretion of the treating surgeon. Critical elements of treatment will be registered and outcome will be monitored at regular intervals over the subsequent 12 months. The primary outcome measure is the Disabilities of the Arm, Shoulder, and Hand score. Secondary outcome measures are the Constant score, pain level at both sides, range of motion of the elbow and shoulder joint at both sides, radiographic healing, rate of complications and (secondary) interventions, health-related quality of life (Short-Form 36 and EuroQol-5D), time to resumption of ADL/work, and cost-effectiveness. Data will be analyzed using univariate and multivariable analyses (including mixed effects regression analysis). The cost-effectiveness analysis will be performed from a societal perspective. Discussion Successful completion of this trial will provide evidence on the effectiveness of operative versus non-operative treatment of patients with a humeral shaft fracture. Trial registration The trial is registered at the Netherlands Trial Register (NTR3617). PMID:24517194

2014-01-01

158

The prognostic value of the fracture level in the treatment of Gartland type III supracondylar humeral fracture in children.  

PubMed

A small proportion of children with Gartland type III supracondylar humeral fracture (SCHF) experience troubling limited or delayed recovery after operative treatment. We hypothesised that the fracture level relative to the isthmus of the humerus would affect the outcome. We retrospectively reviewed 230 children who underwent closed reduction and percutaneous pinning (CRPP) for their Gartland type III SCHFs between March 2003 and December 2012. There were 144 boys and 86 girls, with the mean age of six years (1.1 to 15.2). The clinico-radiological characteristics and surgical outcomes (recovery of the elbow range of movement, post-operative angulation, and the final Flynn grade) were recorded. Multivariate analysis was employed to identify prognostic factors that influenced outcome, including fracture level. Multivariate analysis revealed that a fracture below the humeral isthmus was significantly associated with poor prognosis in terms of the range of elbow movement (p < 0.001), angulation (p = 0.001) and Flynn grade (p = 0.003). Age over ten years was also a poor prognostic factor for recovery of the range of elbow movement (p = 0.027). This is the first study demonstrating a subclassification system of Gartland III fractures with prognostic significance. This will guide surgeons in peri-operative planning and counselling as well as directing future research aimed at improving outcomes. PMID:25568427

Kang, S; Kam, M; Miraj, F; Park, S-S

2015-01-01

159

Lateral orientation (image)  

MedlinePLUS

A lateral orientation is a position away from the midline of the body. For instance, the arms are lateral to the ... ears are lateral to the head. A medial orientation is a position toward the midline of the ...

160

Lateral Neck Injury Assessments in Side Impact Using Post Mortem Human Subject Tests  

PubMed Central

Current neck injury criteria are based on matching upper cervical spine injuries from piglet tests to airbag deployment loads and pairing kinematics from child dummies. These “child-based” scaled data together with adult human cadaver tolerances in axial loading are used to specify neck injury thresholds in axial compression and tension, and flexion and extension moment about the occipital condyles; no thresholds are specified for any other force or moment including lateral bending. The objective of this study was to develop a testing methodology and to determine the lateral bending moment injury threshold under coronal loading. Post mortem human subjects (PMHS) were used. Specimens consisted of whole body and isolated head-neck complexes with intact musculature. Intact specimen positioning included: sitting PMHS upright on a rigid seat, supporting the torso by a plate, maintaining Frankfurt plane horizontal. Isolated head-neck complexes were fixed at T1 with the occiput connected via a custom apparatus to a testing device to induce lateral bending motion. Head angular and linear accelerations and angular velocities were computed using a pyramid nine accelerometer package on the head; specimen-specific physical properties including center of gravity and moments of inertia in the three-dimensions; and equations of equilibrium. These data were used to determine neck loads at the occipital condyles. No specimens sustained injuries, identified by palpation, x-rays, CT, and autopsy. Results from 24 tests indicated that PMHS head-neck complexes can tolerate 75 Nm of coronal moment at low axial load without failure, and this level may be used as an initial estimate of the injury reference value under lateral loading to the human head-neck complex. PMID:22105394

Yoganandan, Narayan; Humm, John; Pintar, Frank A.; Wolfla, Christopher E.; Maiman, Dennis J.

2011-01-01

161

Lateral neck injury assessments in side impact using post mortem human subject tests.  

PubMed

Current neck injury criteria are based on matching upper cervical spine injuries from piglet tests to airbag deployment loads and pairing kinematics from child dummies. These "child-based" scaled data together with adult human cadaver tolerances in axial loading are used to specify neck injury thresholds in axial compression and tension, and flexion and extension moment about the occipital condyles; no thresholds are specified for any other force or moment including lateral bending. The objective of this study was to develop a testing methodology and to determine the lateral bending moment injury threshold under coronal loading. Post mortem human subjects (PMHS) were used. Specimens consisted of whole body and isolated head-neck complexes with intact musculature. Intact specimen positioning included: sitting PMHS upright on a rigid seat, supporting the torso by a plate, maintaining Frankfurt plane horizontal. Isolated head-neck complexes were fixed at T1 with the occiput connected via a custom apparatus to a testing device to induce lateral bending motion. Head angular and linear accelerations and angular velocities were computed using a pyramid nine accelerometer package on the head; specimen-specific physical properties including center of gravity and moments of inertia in the three-dimensions; and equations of equilibrium. These data were used to determine neck loads at the occipital condyles. No specimens sustained injuries, identified by palpation, x-rays, CT, and autopsy. Results from 24 tests indicated that PMHS head-neck complexes can tolerate 75 Nm of coronal moment at low axial load without failure, and this level may be used as an initial estimate of the injury reference value under lateral loading to the human head-neck complex. PMID:22105394

Yoganandan, Narayan; Humm, John; Pintar, Frank A; Wolfla, Christopher E; Maiman, Dennis J

2011-01-01

162

Lateral collateral ligament (image)  

MedlinePLUS

The lateral collateral ligament connects the end of the femur (thigh) to the top of the fibula (the thin ... that runs next to the shin bone). The lateral collateral ligament provides stability against varus stress. Varus ...

163

Lateral plantar neuropathy.  

PubMed

We report 8 cases of lateral plantar neuropathy (LPN). All had sensory impairment over the territory of the lateral plantar nerve. Near-nerve needle sensory nerve conduction study (NCS) of the plantar nerves showed abnormality confined to the lateral plantar nerve, confirming LPN. The most common cause for LPN was trauma and the most common site of injury was at the passage of the lateral plantar nerve through the abductor tunnel at the instep of the foot. PMID:10454719

Oh, S J; Kwon, K H; Hah, J S; Kim, D E; Demirci, M

1999-09-01

164

CD146 as a new marker for an increased chondroprogenitor cell sub-population in the later stages of osteoarthritis.  

PubMed

Cartilage-derived mesenchymal stem cells (MSCs) have been isolated with different methods. In this study lateral and medial femoral condyles were respectively collected from patients with late-stage osteoarthritis during the total knee arthroplasty. After digestion of the cartilage tissues with type II collagenase and analysis by fluorescence-activated cell sorting (FACS) with CD146, a chondroprogenitor cell sub-population were isolated and purified. The expression of other MSC-associated markers in the CD146+ chondroprogenitors was analyzed by flow cytometry. Multi-lineage differentiation capacity of CD146+ chondroprogenitors was compared with that of unsorted chondrocytes and adipose-derived MSCs (ADMSCs). Higher percentage of CD146+ chondroprogenitors isolated from the medial femoral condyles was observed than that from the lateral. CD146+ chondroprogenitors expressed high levels of MSC-specific surface antigens, and showed higher chondrogenesis capacity than ADMSCs and unsorted chondrocytes in a 3D cell pellet culture model. Thus CD146 might be a new cell surface marker for cartilage progenitor cell population in the late-stage osteoarthritis. PMID:25266708

Su, Xinlin; Zuo, Wei; Wu, Zhihong; Chen, Jun; Wu, Nan; Ma, Pei; Xia, Zenan; Jiang, Chao; Ye, Zixing; Liu, Sen; Liu, Jiaqi; Zhou, Guangqian; Wan, Chao; Qiu, Guixing

2015-01-01

165

Long-term results of low rotation humeral osteotomy in children with Erb's obstetric brachial plexus palsy.  

PubMed

Seventeen children with Erb's (C5/6 and C5/6/7 types) obstetric brachial plexus palsy who underwent low rotation humeral osteotomy to treat internal rotation contracture of the shoulder were recalled back to the clinic at a mean of 10 (range 8-14) years after surgery. Eight were male and nine female with mean age of 16 (range 13-20) years. The osteotomy procedure was done at a mean age of 6 (range 5-8) years. Preoperative, early postoperative, and late postoperative motor assessments were compared. There was no recurrence of the internal rotation posturing of the shoulder and there was maintenance of the improvements in elbow extension deficit and forearm rotation. The most surprising finding was a significant (P = 0.003) decrease in shoulder abduction on long-term follow-up (the mean shoulder abduction was 135 degrees , 146 degrees and 109 degrees measured pre-, early post- and late postoperatively, respectively). There was no correlation between changes in shoulder abduction and the radiological score of the shoulder. PMID:19675029

Al-Qattan, M M; Al-Husainan, H; Al-Otaibi, A; El-Sharkawy, M S

2009-08-01

166

[Multivariate genetic analysis of canine hip and elbow dysplasia as well as humeral osteochondrosis in the Bernese mountain dog].  

PubMed

In the present study genetic parameters for canine hip dysplasia (CHD), canine elbow dysplasia (CED) and osteochondrosis dissecans of the humeral head (OCD) were analysed in Bernese mountain dogs. The data set included the official scores for CHD and CED from 5534 Bernese mountain dogs born in the years 1995-2008. A multivariate linear animal model was employed to estimate heritabilities, additive genetic and residual correlations using residual maximum likelihood (REML). Heritability estimates were h2 = 0.26 for CHD, h2 = 0.22 for CED and h2 = 0.40 for OCD. The additive genetic correlation between CHD and CED was 0.31, between CHD and OCD 0.25, and between CED und OCD -0.49. A further multivariate analysis of the prevalence of the FCP (fragmented coronoid processus), CHD and OCD revealed a heritability of h2 = 0.59 for FCP. The additive genetic correlations among FCP and CHD as well CED except FCP were positive, but negative with OCD. Multivariately estimated breeding values will lead to higher genetic progress because the correlation structure of the traits can be taken into account and possible genetic antagonisms among traits are better reflected in the breeding values. PMID:21141279

Hartmann, Peter; Stock, Kathrin Friederike; Distl, Ottmar

2010-01-01

167

Evolution of bone compactness in extant and extinct moles (Talpidae): exploring humeral microstructure in small fossorial mammals  

PubMed Central

Background Talpids include forms with different degree of fossoriality, with major specializations in the humerus in the case of the fully fossorial moles. We studied the humeral microanatomy of eleven extant and eight extinct talpid taxa of different lifestyles and of two non-fossorial outgroups and examined the effects of size and phylogeny. We tested the hypothesis that bone microanatomy is different in highly derived humeri of fossorial taxa than in terrestrial and semi-aquatic ones, likely due to special mechanical strains to which they are exposed to during digging. This study is the first comprehensive examination of histological parameters in an ecologically diverse and small-sized mammalian clade. Results No pattern of global bone compactness was found in the humeri of talpids that could be related to biomechanical specialization, phylogeny or size. The transition zone from the medullary cavity to the cortical compacta was larger and the ellipse ratio smaller in fossorial talpids than in non-fossorial talpids. No differences were detected between the two distantly related fossorial clades, Talpini and Scalopini. Conclusions At this small size, the overall morphology of the humerus plays a predominant role in absorbing the load, and microanatomical features such as an increase in bone compactness are less important, perhaps due to insufficient gravitational effects. The ellipse ratio of bone compactness shows relatively high intraspecific variation, and therefore predictions from this ratio based on single specimens are invalid. PMID:23442022

2013-01-01

168

Diagnostic accuracy of cone beam computed tomography and conventional multislice spiral tomography in sheep mandibular condyle fractures  

PubMed Central

Objectives The aim of this study was to compare diagnostic accuracy of cone beam CT (CBCT) and multislice CT in artificially created fractures of the sheep mandibular condyle. Methods 63 full-thickness sheep heads were used in this study. Two surgeons created the fractures, which were either displaced or non-displaced. CBCT images were acquired by the NewTom 3G® CBCT scanner (NIM, Verona, Italy) and CT imaging was performed using the Toshiba Aquillon® multislice CT scanner (Toshiba Medical Systems, Otawara, Japan). Two-dimensional (2D) cross-sectional images and three-dimensional (3D) reconstructions were evaluated by two observers who were asked to determine the presence or absence of fracture and displacement, the type of fracture, anatomical localization and type of displacement. The naked-eye inspection during surgery served as the gold standard. Inter- and intra-observer agreements were calculated with weighted kappa statistics. The receiver operating characteristics (ROC) curve analyses were used to compare statistically the area under the curve (AUC) of both imaging modalities. Results Kappa coefficients of intra- and interobserver agreement scores varied between 0.56 – 0.98, which were classified as moderate and excellent, respectively. There was no statistically significant difference between the imaging modalities, which were both sensitive and specific for the diagnosis of sheep condylar fractures. Conclusions This study confirms that CBCT is similar to CT in the diagnosis of different types of experimentally created sheep condylar fractures and can provide a cost- and dose-effective diagnostic option. PMID:20729182

Sirin, Y; Guven, K; Horasan, S; Sencan, S

2010-01-01

169

Mandibular condyle lesions related to age at onset and subtypes of juvenile rheumatoid arthritis in 15-year-old children.  

PubMed

The severity of lesions in the temporomandibular joint (TMJ) area and their association with age at onset, the various forms of juvenile rheumatoid arthritis (JRA), and certain serologic tests for rheumatoid factor (RF), antinuclear antibodies (ANA), and human leukocyte antigen (HLA)-B27 were determined in 15-yr-old children. The series comprised 121 JRA children, 78 girls and 43 boys, in whom an analysis had recently been made of the relation of TMJ lesions to jaw movement and occlusal status. The mean age at onset was 7.3 yr, the girls contracting JRA earlier than the boys. Also, the girls with lesions in the TMJ area were significantly younger than those with no lesions. TMJ abnormalities were found in 50% of cases with a pauciarticular or systemic onset, but in 72% of those representing the polyarticular subtype. Flattened condyles and grave lesions were equally represented in all subgroups and in both sexes. A crossover from onset type to present diagnosis was found in 30% of the cases, mostly from pauciarticular to polyarthritis, which also increased the risk of TMJ lesions from 50 to 60%. RF, ANA, or HLA-B27 alone did not seem to be associated with a risk of TMJ abnormalities. Maximal opening capacity is more restricted in patients with early onset or a polyarticular mode of JRA. Since the TMJ is affected in more than half of JRA children, regular measurements of maximal movements of the mandible or roentgenologic examinations of the TMJ are essential for their optimal treatment. PMID:8248736

Karhulahti, T; Ylijoki, H; Rönning, O

1993-10-01

170

Lateral flow strip assay  

DOEpatents

A lateral flow strip assay apparatus comprising a housing; a lateral flow strip in the housing, the lateral flow strip having a receiving portion; a sample collection unit; and a reagent reservoir. Saliva and/or buccal cells are collected from an individual using the sample collection unit. The sample collection unit is immersed in the reagent reservoir. The tip of the lateral flow strip is immersed in the reservoir and the reagent/sample mixture wicks up into the lateral flow strip to perform the assay.

Miles, Robin R. (Danville, CA); Benett, William J. (Livermore, CA); Coleman, Matthew A. (Oakland, CA); Pearson, Francesca S. (Livermore, CA); Nasarabadi, Shanavaz L. (Livermore, CA)

2011-03-08

171

Bilateral rotational osteotomies of the proximal tibiae and tibial tuberosity distal transfers for the treatment of congenital lateral dislocations of patellae: a case report and literature review.  

PubMed

Congenital dislocation of patella (CDP) causes varying degree of disability. Patients may present as late walkers with asymmetric gait, habitual or recurrent dislocators or even non-walkers if the condition is bilateral. Patellar instability is often associated with soft tissue or bony pathology. Soft tissue anomalies include lateral soft tissue contractures, shortened quadriceps as well as vastus medialis dysplasia (abnormal origin and insertion). Bony anomalies include shallow trochlear groove and hypoplastic patella or lateral femoral condyle. Soft tissue etiologies result in an imbalance of the dynamic forces acting on the patella while in bony etiologies the static stabilizers to resist lateral dislocation are compromised. External tibial torsion is an additional etiology, often under diagnosed due to the difficulty in measuring the Q angle of dislocated patella. We report a case of bilateral congenital lateral dislocations of the patellae treated with bilateral tibial rotational osteotomies with an 8 year and a 4 year follow up. PMID:19464186

Ramaswamy, Rajesh; Kosashvili, Yona; Murnaghan, John J; Yau, Cameron Kin-Mo; Cameron, John C

2009-12-01

172

Open reduction and internal fixation of extracapsular mandibular condyle fractures: a long-term clinical and radiological follow-up of 25 patients  

PubMed Central

Background During the last 2 decades, many studies on the treatment of mandibular condyle fracture have been published. The incidence of mandibular condyle fractures is variable, ranging from 17.5% to 52% of all mandibular fractures. This retrospective study evaluated the long-term clinical and radiological outcomes after surgical treatment of 25 patients with a total of 26 extracapsular condyle fractures. Methods We used 2 types of surgical approaches, the retromandibular retroparotid or preauricular approach. Three kinds of rigid internal fixation plates were used—single plate, double plate, and trapezoidal plate. The following post-operative clinical parameters were evaluated: dental occlusion, facial nerve functionality, skin scarring, and temporomandibular joint functionality. All patients underwent post-operative orthopanoramic radiography and computed tomography. The patients were also monitored for complications such as Frey’s syndrome, infection, salivary fistula, plate fracture, and permanent paralysis of the facial nerve; the patient’s satisfaction was also recorded. Results Of the 25 patients, 80% showed occlusion recovery, 88% had no facial nerve injury, and 88% presented good surgical skin scarring. The patients showed early complete recovery of temporomandibular joint functionality and 72% of them were found to be asymptomatic. The postoperative radiographs of all patients indicated good recovery of the anatomical condylar region, and 80% of them had no postoperative complications. The average degree of patient satisfaction was 8.32 out of 10. Our results confirm that the technique of open reduction and internal fixation in association with postoperative functional rehabilitation therapy should be considered for treating patients with extracapsular condylar fractures. Conclusion The topic of condylar injury has generated more discussion and controversy than any other topic in the field of maxillofacial trauma. We confirm that open reduction and internal fixation is the treatment of choice for patients with neck and sub-condylar mandibular fractures. PMID:25196114

2014-01-01

173

Spontaneous hyaline cartilage regeneration can be induced in an osteochondral defect created in the femoral condyle using a novel double-network hydrogel  

PubMed Central

Background Functional repair of articular osteochondral defects remains a major challenge not only in the field of knee surgery but also in tissue regeneration medicine. The purpose is to clarify whether the spontaneous hyaline cartilage regeneration can be induced in a large osteochondral defect created in the femoral condyle by means of implanting a novel double-network (DN) gel at the bottom of the defect. Methods Twenty-five mature rabbits were used in this study. In the bilateral knees of each animal, we created an osteochondral defect having a diameter of 2.4-mm in the medial condyle. Then, in 21 rabbits, we implanted a DN gel plug into a right knee defect so that a vacant space of 1.5-mm depth (in Group I), 2.5-mm depth (in Group II), or 3.5-mm depth (in Group III) was left. In the left knee, we did not apply any treatment to the defect to obtain the control data. All the rabbits were sacrificed at 4 weeks, and the gross and histological evaluations were performed. The remaining 4 rabbits underwent the same treatment as used in Group II, and real-time PCR analysis was performed at 4 weeks. Results The defect in Group II was filled with a sufficient volume of the hyaline cartilage tissue rich in proteoglycan and type-2 collagen. The Wayne's gross appearance and histology scores showed that Group II was significantly greater than Group I, III, and Control (p < 0.012). The relative expression level of type-2 collagen, aggrecan, and SOX9 mRNAs was significantly greater in Group II than in the control group (p < 0.023). Conclusions This study demonstrated that spontaneous hyaline cartilage regeneration can be induced in vivo in an osteochondral defect created in the femoral condyle by means of implanting the DN gel plug at the bottom of the defect so that an approximately 2-mm deep vacant space was intentionally left in the defect. This fact has prompted us to propose an innovative strategy without cell culture to repair osteochondral lesions in the femoral condyle. PMID:21338528

2011-01-01

174

Hemiarthroplasty of the shoulder joint using a custom-designed high-density nano-hydroxyapatite/polyamide prosthesis with a polyvinyl alcohol hydrogel humeral head surface in rabbits.  

PubMed

In this study, a novel custom-designed high-density nano-hydroxyapatite/polyamide (n-HA/PA) prosthesis with a polyvinyl alcohol (PVA) hydrogel humeral head surface was employed to repair the shoulder joint head for hemiarthroplasty in rabbits. The prosthesis was fabricated using three-dimensional computed tomography and computer-aided design and computer-aided manufacturing systems for perfect fitting. Sixteen New Zealand white rabbits underwent humeral head excision, and received the composite prostheses for hemiarthroplasty. The implant sites were free from suppuration and necrosis at all periods. The X-ray results showed that there was a clear space between the prosthesis head and the glenoid surface, and the joint capsules and surfaces of the glenoid and PVA were well preserved without any damage during the whole inspection period. A high density of bone was observed around the firmware part of the prosthesis. Histological results revealed that significant osteogenesis was surrounding the firmware part, and the joint space was clear and the cartilage of the upper joint surface was basically intact. There was no visible absorption of the joint surfaces even after 3 months of continuous functional motions. The maximum tensile strength between the prosthesis and host bone reached 2.63?MPa at the 12th week postimplantation. In conclusion, the customized prosthesis by combination of PVA and high-density n-HA/PA has excellent biocompatibility and biological fixation, and offers a promising substitute for both the cartilage and the bone of the humeral head in a rabbit model as level V evidence. PMID:24404998

Guo, Yongwen; Guo, Jun; Bai, Ding; Wang, Hang; Zheng, Xiaohui; Guo, Weihua; Tian, Weidong

2014-07-01

175

Lateral epicondylosis and calcific tendonitis in a golfer: a case report and literature review  

PubMed Central

Objective To detail the progress of a young female amateur golfer who developed chronic left arm pain while playing golf 8 months prior to her first treatment visit. Clinical Features Findings included pain slightly distal to the lateral epicondyle of the elbow, decreased grip strength, and positive orthopedic testing. Diagnostic ultrasound showed thickening of the common extensor tendon origin indicating lateral epicondylosis. Radiographs revealed an oval shaped calcified density in the soft tissue adjacent to the lateral humeral epicondyle, indicating calcific tendonitis of the common extensor tendon origin. Intervention and Outcome Conventional care was aimed at decreasing the repetitive load on the common extensor tendon, specifically the extensor carpi radialis brevis. Soft tissue techniques, exercises and stretches, and an elbow brace helped to reduce repetitive strain. Outcome measures included subjective pain ratings, and follow up imaging 10 weeks after treatment began. Conclusion A young female amateur golfer with chronic arm pain diagnosed as lateral epicondylosis and calcific tendonitis was relieved of her pain after 7 treatments over 10 weeks of soft tissue and physical therapy focusing specifically on optimal healing and decreasing the repetitive load on the extensor carpi radialis brevis. PMID:22131570

Yuill, Erik A.; Lum, Grant

2011-01-01

176

Ultrasound-guided interscalene-supraclavicular block for an intramedullary nailing of a pathologic humeral fracture: practical application of ultrasound-guided regional anesthesia.  

PubMed

Fractures of the proximal upper extremity present a challenge to the anesthesia provider when administering a regional anesthetic because the dermatomal distribution of the upper extremity requires more local anesthetic coverage than any single brachial plexus nerve block can provide. A 60-year-old woman underwent intramedullary nailing of a pathologic humeral fracture using a combination of regional and general anesthesia. This case study shows how ultrasound guidance permitted the performance of both an interscalene and supraclavicular nerve block for a single procedure without the increased volume of local anesthetic that would normally be required, while still providing complete coverage of the entire upper extremity. PMID:25109160

Falyar, Christian R; Grossman, Eric C

2014-06-01

177

Primary Lateral Sclerosis  

MedlinePLUS

... When symptoms begin, PLS may be mistaken for amyotrophic lateral sclerosis (ALS) or spastic paraplegia. Most neurologists follow an affected ... 1-877-773-4483) Fax: 877-SPF-GIVE ALS Association 1275 K Street, N.W. Suite 1050 ...

178

Amyotrophic Lateral Sclerosis  

MedlinePLUS

Amyotrophic lateral sclerosis (ALS) is a nervous system disease that attacks nerve cells called neurons in your brain and spinal cord. These neurons ... breathing machine can help, but most people with ALS die from respiratory failure. The disease usually strikes ...

179

Laterally bendable belt conveyor  

DOEpatents

An endless, laterally flexible and bendable belt conveyor particularly adapted for coal mining applications in facilitating the transport of the extracted coal up- or downslope and around corners in a continuous manner is disclosed. The conveying means includes a flat rubber belt reinforced along the middle portion thereof along which the major portion of the belt tension is directed so as to cause rotation of the tubular shaped belt when trammed around lateral turns thus preventing excessive belt bulging distortion between adjacent belt supports which would inhibit belt transport. Pretension induced into the fabric reinforced flat rubber belt by conventional belt take-up means supports the load conveyed when the belt conveyor is making lateral turns. The carrying and return portions of the belt are supported and formed into a tubular shape by a plurality of shapers positioned along its length. Each shaper is supported from above by a monorail and includes clusters of idler rollers which support the belt. Additional cluster rollers in each shaper permit the belt supporting roller clusters to rotate in response to the belt's operating tension imposed upon the cluster rollers by induced lateral belt friction forces. The freely rotating roller clusters thus permit the belt to twist on lateral curves without damage to itself while precluding escape of the conveyed material by effectively enclosing it in the tube-shaped, inner belt transport length.

Peterson, William J. (Coraopolis, PA)

1985-01-01

180

Bilateral lateral periodontal cyst.  

PubMed

The bilateral lateral periodontal cyst is a rare nasological entity, which despite clinical and radiological presentation is being diagnosed by histological characteristics. It is asymptomatic in nature and is observed in routine radiography. The aim and objective of this article is to present a rare case of bilateral lateral periodontal cyst in a 14-year-old child. The clinical and radiographical findings, along with its management have been discussed. Enucleation of bilateral cyst without extraction of the adjacent tooth was performed. Lesion samples were sent for histopathological analysis. The histopathological analysis revealed a thin, non keratinised stratified squamous epithelium resembling reduced enamel epithelium. Epithelial plaques were also seen. A clinicopathological correlation incorporating the surgical, radiographical and gold standard histopathological findings was obtained to suggest the final diagnosis of the bilateral lateral periodontal cyst. PMID:23667246

Govil, Somya; Gupta, Vishesh; Misra, Neeta; Misra, Pradyumna

2013-01-01

181

[Adult lateral meniscus].  

PubMed

Meniscal lesion does not mean meniscectomy and this is particularly true for the lateral meniscus. The reputation of mildness of the meniscectomy is usurped. The rate of joint space narrowing after lateral meniscectomy is of 40% at a follow-up of 13 years compared to 28% for the medial meniscus (symposium SFA 1996). Several arguments explain those results: biomechanical: the lateral meniscus contributes to the congruence; particularly the lateral meniscus is the zone where antero-posterior translational during knee flexion is 12 mm. The pejorative effects of lateral meniscectomy have conducted, more though to the medial meniscus, to the concept of meniscal economy. Lateral meniscectomy must be as partial as possible. Particularly, a discoid meniscus presenting a complete tear should be treated by a meniscoplasty in order to shape the meniscus in a more anatomic form than a total meniscectomy. Lateral meniscectomy is indicated in complex or horizontal cleavage, symptomatic, on stable knees. A particular case is the cyst of the lateral meniscus. It is a cystic subcutaneous formation, usual consequence of a horizontal cleaved meniscus of which the particularity is that it opens besides the articulation. The strategy must not consist in the isolated treatment of the cyst. This pathology should be addressed by an arthroscopic meniscectomy reaching the meniscosynovial junction at the level of the cyst. Meniscal repair must be proposed every time if possible. Criteria of reparability are better studied on MRI. Preoperatively MRI is the first choice radiological exam. Two essential indications can be held back: the vertical peripheral longitudinal lesion is on the non-vascularized area, and the horizontal cleaving of the junior athlete (if the cleaving remains purely intra meniscal). Meniscal repair is highly performed when the meniscal tear is associated to a rupture of the ACL (simultaneous reconstruction of the LCA). Postoperative outcome is different of that of a "simple" arthroscopic meniscectomy. The healing process being slow, it suits to protect the suture by a splint in the first month, and with an exclusion of sports with knee torsion during 6 months. Functional results (absence of secondary meniscectomy) and anatomical results (reality of the cicatrisation) are good in 77% of cases (symposium of the French Society of Arthroscopy 2003) at a follow-up of 55 months. Survivorship analysis indicates that majority of the failures occur within two years: this testifies a default of primary cicatrisation. At the studied follow-up, meniscal repair was efficient to protect the cartilage. Lateral meniscus results are better that medial meniscus one. Those data support indications: All suspicion of meniscal lesion must have an MRI preoperatively to confirm the lesion, to localize her and to search criteria of reparability; All vertical longitudinal peripheral lesions can and must be repaired especially in young patients and children; All horizontal cleaving of the junior athletes should be treated by open repair; surgical abstention must be proposed when the lesion is non symptomatic, or when lesion is limited and associated to an ACL tear (in that case isolated ACL reconstruction is proposed), or when clinical symptoms are minimal; Meniscectomy, always arthroscopic, is proposed for a symptomatic lesion in the avascular zone or for a deep horizontal cleavage or a complex tear; Tear of the discoid meniscus should be treated by meniscoplasty. A painful knee after lateral meniscectomy might be due to a too limited initial meniscectomy: an iterative meniscectomy may be indicated or lateral femorotibial arthritis, especially after subtotal or total meniscectomy. In this last case and after failure of usual medical treatment such as viscosupplementation surgery may be indicated. Osteotomy in order to unload the lateral femorotibial compartment gives a partial response as the shearing forces remain. This osteotomy is indicated only if the lower limb axis is normal or in valgus. Meniscal allograft is an option in young patients

Beaufils, P; Hardy, P; Chambat, P; Clavert, P; Djian, P; Frank, A; Hulet, C; Potel, J-F; Verdonk, R

2006-09-01

182

Delete It Later  

NSDL National Science Digital Library

Have you ever wanted to delete a Facebook or Twitter post after it was published? It can be a good practice but can be tough to remember. Delete It Later allows users to schedule the posting of statuses, updates, and photos along with the option to schedule when the content will be removed. This version is compatible with all operating systems.

2014-05-22

183

Effects of humeral head compression taping on the isokinetic strength of the shoulder external rotator muscle in patients with rotator cuff tendinitis  

PubMed Central

[Purpose] The purpose of this study was to examine the effects of humeral head compression taping (HHCT) on the strength of the shoulder external rotator muscle in patients with rotator cuff tendinitis. [Subjects and Methods] Twenty patients with rotator cuff tendinitis were recruited. The shoulder external rotator strength was measured using a Biodex isokinetic dynamometer system. A paired t-test was performed to evaluate within-group differences in the strength of the shoulder external rotator muscle. [Results] Significantly higher shoulder external rotator peak torque and peak torque per body weight were found in the HHCT condition than in the no-taping condition. [Conclusion] HHCT may effectively increase the shoulder external rotator muscle strength in patients with rotator cuff tendinitis. PMID:25642053

Kim, Moon-Hwan; Oh, Jae-Seop

2015-01-01

184

The validity of ultrasonographic assessment in cubital tunnel syndrome: the value of a cubital-to-humeral nerve area ratio (CHR) combined with morphologic features.  

PubMed

Diagnosis of a typical idiopathic cubital tunnel syndrome (CuTS) is straight forward but the work-up of mild forms is clinically challenging. The diagnostic value of high-resolution ultrasound (HRUS) relying solely on nerve measurements is doubtful. Additional textural analysis of the nerve may possibly overcome this drawback. Thirty-eight prospectively enrolled patients with idiopathic CuTS and 23 healthy volunteers underwent standardized HRUS. A cubital-to-humeral nerve area ratio (CHR) was calculated and the texture of the most swollen nerve segment assessed. CHR was significantly different among patients and volunteers (p<0.001) but with a marked overlap. Combination of at least partial inner fascicular masking plus a CHR>1.4 showed a positive linear coherence with idiopathic CuTS at a specificity>95% and a PPV>90%. Thus, the combined textural analysis and CHR calculation seems a powerful tool for the sonographic diagnosis of idiopathic CuTS. PMID:20133042

Gruber, Hannes; Glodny, Bernhard; Peer, Siegfried

2010-03-01

185

[Amyotrophic lateral sclerosis].  

PubMed

Amyotrophic lateral sclerosis (ALS) is an aggressive degeneration of upper and lower motor neurons and thus affects both the central and the peripheral nervous system. Clinically, the disease is characterized by rapidly progressing atrophy and paresis of all muscle groups with a letal outcome after three to six years due to paresis of the respiratory muscles. So far, no causal treatment is known. PMID:25632606

Hübers, Annemarie; Weishaupt, Jochen H; Ludolph, Albert C

2014-10-01

186

Amyotrophic lateral sclerosis.  

PubMed

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder affecting 20,000 to 30,000 people in the United States. The mainstay of care of patients affected by this disease is supportive and given the multifaceted nature of their needs is provided most efficiently through multidisciplinary clinics that have shown to prolong survival and improve quality of life. The authors discuss in detail evidence-based management of individuals affected by this condition. PMID:25520025

Malik, Rabia; Lui, Andrew; Lomen-Hoerth, Catherine

2014-11-01

187

Lateral transperitoneal laparoscopic adrenalectomy  

Microsoft Academic Search

Several laparoscopic approaches to the adrenal gland have been described. The lateral transperitoneal approach has several\\u000a distinct advantages when contrasted with other techniques for laparoscopic adrenalectomy (LA). We present our technique and\\u000a results obtained in 50 consecutive transperitoneal LAs. We review 50 consecutive laparoscopic adrenalectomies (28 female,\\u000a 19 male) performed from 1993 to 1998. S.J. Shichman or R.E. Sosa was

Steven J. Shichman; C. D. Anthony Herndon; R. Ernest Sosa; Giles F. Whalen; Dougald C. MacGillivray; Carl D. Malchoff; E. Darracott Vaughan

1999-01-01

188

Start School Later  

NSDL National Science Digital Library

Last month, Pediatrics, the official journal of the American Academy of Pediatrics (AAP), issued a formal policy statement concerning School Start Times for Adolescents (http://pediatrics.aappublications.org/content/early/2014/08/19/peds.2014-1697.abstract?sid=3f739b0e-a552-4a4a-bd0a-907809e20255). In essence, the AAP called for schools to start later, citing sleep deprivation among teenagers as â??an important public health issue.â?ť This site from Start School Later, a group advocating for â??health, safety and equity in education,â?ť provides good, if somewhat one-sided, information on the topic. If youâ??re unfamiliar, start with Research & Info, which provides links to a number of informative sites about adolescent sleep needs and the impact of early school start times. Success Stories takes readers to schools around the country that have experimented with, and benefited from, later start times. If you're inspired, you can also Get Involved. Whatever your position on the issue, this is an informative and interesting site.

189

Lateral periodontal cyst.  

PubMed

The lateral periodontal cyst (LPC) is a harmless developmental aberration derived from odontogenic epithelia lying between the roots of vital teeth. The exact histogenesis of LPC is a matter of debate but therapy is usually only required to maintain stable periodontal conditions and in case of evidence for growth of the cyst. We report on a case of LPC where successful surgical therapy had initialized osseous restoration. We further discuss the value of histological findings to substantiate a clinical and radiological diagnosis. PMID:24982228

Friedrich, Reinhard E; Scheuer, Hanna A; Zustin, Jozef

2014-01-01

190

Amyotrophic Lateral Sclerosis (ALS)  

NSDL National Science Digital Library

This patient education program explains amyotrophic lateral sclerosis (ALS or Lou Gehrig's Disease) including the causes, symptoms, diagnosis and treatment options. This resource is a MedlinePlus Interactive Health Tutorial from the National Library of Medicine, designed and developed by the Patient Education Institute. NOTE: This tutorial requires a special Flash plug-in, version 4 or above. If you do not have Flash, you will be prompted to obtain a free download of the software before you start the tutorial. You will also need an Acrobat Reader, available as a free download, in order to view the Reference Summary.

Patient Education Institute

191

Quantitative Anatomical Study of Tailored Far-Lateral Approach for the VA-PICA Regions.  

PubMed

Objective?The extent of the far-lateral approach (FLA) has not yet been quantified for the region of the vertebral and posterior inferior cerebellar arteries (VA-PICA). We quantitatively analyzed six main sequential steps of the FLA. Methods?A modified small FLA (msFLA) and a classic large FLA (clFLA) were performed sequentially on both sides of five cadaveric heads. A frameless navigational system was used to quantify the angle of attack for the origin (T1) and lateral medullary segment (T2) of the PICA and the surgical area of exposure above and below the vagus nerve (cranial nerve [CN] X). Results?The total area of exposure above CN X increased significantly (p??0.05). C1 hemilaminectomy increased (p?condyle increased (p?

Kim, Young-Don; Mendes, George A C; Seoane, Pablo; Agrawal, Abhishek; Maramreddy, Naveen; Nakaji, Peter; Spetzler, Robert F; Preul, Mark C

2015-02-01

192

Timely recognition of traumatic atlanto-occipital dislocation in a child based on occipital condyle-C1 interval analysis: excellent neurological recovery.  

PubMed

A case of atlanto-occipital dislocation (AOD) is presented to illustrate the importance of subtle imaging findings and the occipital condyle-C1 interval (CCI) measurement in the evaluation of high cervical spine injury. Although AOD is commonly considered to be fatal, recently there have been an increasing number of reports of children surviving this injury. Prompt recognition and treatment of AOD are crucial for survival. The authors present a case of an 8-year-old boy who sustained a destabilizing injury without bone disruption but with ligamentous tears that rendered his cervical spine unstable from the occiput to the C-1 level. On admission, imaging findings were consistent with tectorial membrane damage, perimedullary subarachnoid hemorrhage, and extraaxial blood from the clivus to the C-2 level. Most standard cervical spine radiological indices were within normal limits except the CCI. After initial management in a cervical collar, the patient was placed in halo vest, and subsequently underwent occiput to C-3 fusion. Timely recognition of the injury and subsequent craniocervical stabilization with internal fixation resulted in full neurological recovery. This report supports CCI as a valuable index for the prompt recognition of AOD. It also supports recent literature suggesting that AOD is a survivable injury with the possibility for an excellent neurological recovery. PMID:20433259

Gluncic, Vicko; Turner, Michael; Kranzler, Leonard; Frim, David

2010-05-01

193

Evaluation of injectable strontium-containing borate bioactive glass cement with enhanced osteogenic capacity in a critical-sized rabbit femoral condyle defect model.  

PubMed

The development of a new generation of injectable bone cements that are bioactive and have enhanced osteogenic capacity for rapid osseointegration is receiving considerable interest. In this study, a novel injectable cement (designated Sr-BBG) composed of strontium-doped borate bioactive glass particles and a chitosan-based bonding phase was prepared and evaluated in vitro and in vivo. The bioactive glass provided the benefits of bioactivity, conversion to hydroxyapatite, and the ability to stimulate osteogenesis, while the chitosan provided a cohesive biocompatible and biodegradable bonding phase. The Sr-BBG cement showed the ability to set in situ (initial setting time = 11.6 ± 1.2 min) and a compressive strength of 19 ± 1 MPa. The Sr-BBG cement enhanced the proliferation and osteogenic differentiation of human bone marrow-derived mesenchymal stem cells in vitro when compared to a similar cement (BBG) composed of chitosan-bonded borate bioactive glass particles without Sr. Microcomputed tomography and histology of critical-sized rabbit femoral condyle defects implanted with the cements showed the osteogenic capacity of the Sr-BBG cement. New bone was observed at different distances from the Sr-BBG implants within eight weeks. The bone-implant contact index was significantly higher for the Sr-BBG implant than it was for the BBG implant. Together, the results indicate that this Sr-BBG cement is a promising implant for healing irregularly shaped bone defects using minimally invasive surgery. PMID:25591177

Zhang, Yadong; Cui, Xu; Zhao, Shichang; Wang, Hui; Rahaman, Mohamed N; Liu, Zhongtang; Huang, Wenhai; Zhang, Changqing

2015-02-01

194

Lateral conduction infrared photodetector  

DOEpatents

A photodetector for detecting infrared light in a wavelength range of 3-25 .mu.m is disclosed. The photodetector has a mesa structure formed from semiconductor layers which include a type-II superlattice formed of alternating layers of InAs and In.sub.xGa.sub.1-xSb with 0.ltoreq.x.ltoreq.0.5. Impurity doped regions are formed on sidewalls of the mesa structure to provide for a lateral conduction of photo-generated carriers which can provide an increased carrier mobility and a reduced surface recombination. An optional bias electrode can be used in the photodetector to control and vary a cut-off wavelength or a depletion width therein. The photodetector can be formed as a single-color or multi-color device, and can also be used to form a focal plane array which is compatible with conventional read-out integrated circuits.

Kim, Jin K. (Albuquerque, NM); Carroll, Malcolm S. (Albuquerque, NM)

2011-09-20

195

The Efficacy of Intra-Articular Injections for Pain Control Following the Closed Reduction and Percutaneous Pinning of Pediatric Supracondylar Humeral Fractures  

PubMed Central

Background: The purpose of this single-blinded, randomized, controlled trial was to compare the analgesic efficacy of intra-articular injections of bupivacaine or ropivacaine with that of no injection for postoperative pain control after the operative treatment of supracondylar humeral fractures in a pediatric population. Methods: Subjects (n = 124) were randomized to treatment with 0.25% bupivacaine (Group B) (n = 42), 0.20% ropivacaine (Group R) (n = 39), or no injection (Group C) (n = 43). The opioid doses and the times of administration as well as child-reported pain severity (Faces Pain Scale-Revised) and parent-reported pain severity (Total Quality Pain Management survey) were recorded. Results: The proportion of subjects who required morphine and/or fentanyl injections was significantly (p = 0.004) lower in Group B (10%) as compared with Group R (36%) and Group C (44%). On the basis of the log-rank test, the opioid-free survival rates were significantly greater in Group B as compared to Groups C and R. Total opioid consumption (morphine equivalent mg/kg) in the first seventy-two hours postoperatively was significantly less in Group B as compared with Group C (mean difference, 0.225; [95% confidence interval (CI), 0.0152 to 0.435]; p = 0.036). Parent-reported pain scores were also significantly lower in Group B as compared with both Group C (mean difference, 1.81 [95% CI, 0.38 to 3.25]; p = 0.014) and Group R (mean difference, 1.66; 95% CI, 0.20 to 3.12; p = 0.027). There were no significant differences across the three groups in terms of self-reported pain. Differences between Groups R and C were not significant for any of the outcome variables. Conclusions: The intra-articular injection of 0.25% bupivacaine significantly improves postoperative pain control following the closed reduction and percutaneous pinning of supracondylar humeral fractures in pediatric patients. Level of Evidence: Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence. PMID:22878686

Georgopoulos, Gaia; Carry, Patrick; Pan, Zhaoxing; Chang, Frank; Heare, Travis; Rhodes, Jason; Hotchkiss, Mark; Miller, Nancy H.; Erickson, Mark

2012-01-01

196

Laterally oscillating nitinol engine  

SciTech Connect

This patent describes a laterally oscillating nitinol engine comprising: a first L-shaped drive member journalled for pivoting horizontal oscillation about the juncture of the legs of the L-shaped member, a second drive member journalled for pivoting about a point proximate the outboard end of the shorter leg of the L-shaped member at a distance from the pivot journal of the L-shaped member, a bearing block secured to the end of longer leg of the L-shaped and having a guide hole. The second member extending through the guide hole and arranged to reciprocate therein, a shape memory alloy power element disposed in flexure secured at its ends to the bearing block and to the second member intermediate the sliding connection with the bearing block and the pivotal connection of the second member, means for disposing different temperature baths below the element whereby as the drive members oscillate about their journals the element alternately dips into one bath and then the other, and means for absorbing a portion of the energy developed by the engine and moving the power element from the cold bath to the hot bath.

Banks, R.

1987-09-08

197

“8 Plate”: An Alternative Device to Fix Highly Recurrent Traumatic Anterior Gleno-Humeral Instability in Patients with Severe Impairment of the Anterior Capsule  

PubMed Central

Background: There is still debate about the best treatment option for highly recurrent anterior shoulder dislocation in patients with severe impairment of the anterior capsule and/or recurrence after either arthroscopic or open capsulorrhaphy. Materials and Methods: The clinical and radiological findings of 7 patients treated with an open capsulorrhaphy stabilized with an “8 plate” for a highly recurrent traumatic anterior shoulder dislocation with severe impairment of the anterior capsule and a large Bankart lesion were retrospectively reviewed. Follow-up evaluation included VAS for pain, Constant-Murley, Simple Shoulder Test, ASES, UCLA, Quick DASH, Rowe, Walsch-Duplay scores, as well as X-rays of the operated shoulder. Results: At follow-up none of the patients reported subsequent dislocations. Range of motion of the shoulder was complete in all cases, but one. Results of the functional scoring systems were satisfactory. X-rays showed no osteolysis and good position of the plate. Conclusion: To our knowledge, this is the first report in the literature about an open capsular tensioning and Bankart lesion repair performed with an “8 plate”. We believe that this is a reliable and effective procedure to address traumatic anterior re-dislocation of the gleno-humeral joint when the capsule is extensively torn and frayed or in revision cases. Moreover the “8 plate” is ideal to be applied in such a narrow space on the slant surface of the scapular neck close to the glenoid rim. PMID:25621080

Tudisco, C; Bisicchia, S; Savarese, E; Ippolito, E

2014-01-01

198

The scale-up of a tissue engineered porous hydroxyapatite polymer composite scaffold for use in bone repair: An ovine femoral condyle defect study.  

PubMed

The development of an osteogenic bone graft substitute has important practical and cost implications in many branches of medicine where bone regeneration is required. Previous in vitro and small animal (murine) in vivo studies highlighted a porous hydroxyapatite/poly (dl-lactic acid) composite scaffold in combination with skeletal stem cells (SSCs) as a potential bone graft substitute candidate. The aim of the current study was to scale up the bone cell-scaffold construct to large animals and examine the potential for repair of a critical-sized defect via an ovine model. SSC seeded scaffolds (and unseeded scaffold controls) were implanted bilaterally into ovine femoral condyle critical defects for 3 months. A parallel in vitro analysis of ovine SSC seeded scaffolds was also performed. Post mortem mechanical indentation testing showed the bone strengths of the defect sites were 20% (controls) and 11% (SSC seeded scaffolds) those of normal cancellous bone (p?

Tayton, Edward; Purcell, Matthew; Smith, James O; Lanham, Stuart; Howdle, Steven M; Shakesheff, Kevin M; Goodship, Allen; Blunn, Gordon; Fowler, Darren; Dunlop, Douglas G; Oreffo, Richard O C

2015-04-01

199

Reflexive Planning for Later Life  

Microsoft Academic Search

Informed by Giddens’ (1991) concept of reflexive life planning and the notion of later life as a time of increasing social and financial risk, this research explores the idea of reflexive planning for later life. We utilize a conceptual model that incorporates three types of planning for later life: public protection, self-insurance, and self-protection. Drawing on qualitative, life-history data from

Margaret A. Denton; Candace L. Kemp; Susan French; Amiram Gafni; Anju Joshi; Carolyn J. Rosenthal; Sharon Davies

2004-01-01

200

Amyotrophic lateral sclerosis  

PubMed Central

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterised by progressive muscular paralysis reflecting degeneration of motor neurones in the primary motor cortex, corticospinal tracts, brainstem and spinal cord. Incidence (average 1.89 per 100,000/year) and prevalence (average 5.2 per100,000) are relatively uniform in Western countries, although foci of higher frequency occur in the Western Pacific. The mean age of onset for sporadic ALS is about 60 years. Overall, there is a slight male prevalence (M:F ratio~1.5:1). Approximately two thirds of patients with typical ALS have a spinal form of the disease (limb onset) and present with symptoms related to focal muscle weakness and wasting, where the symptoms may start either distally or proximally in the upper and lower limbs. Gradually, spasticity may develop in the weakened atrophic limbs, affecting manual dexterity and gait. Patients with bulbar onset ALS usually present with dysarthria and dysphagia for solid or liquids, and limbs symptoms can develop almost simultaneously with bulbar symptoms, and in the vast majority of cases will occur within 1–2 years. Paralysis is progressive and leads to death due to respiratory failure within 2–3 years for bulbar onset cases and 3–5 years for limb onset ALS cases. Most ALS cases are sporadic but 5–10% of cases are familial, and of these 20% have a mutation of the SOD1 gene and about 2–5% have mutations of the TARDBP (TDP-43) gene. Two percent of apparently sporadic patients have SOD1 mutations, and TARDBP mutations also occur in sporadic cases. The diagnosis is based on clinical history, examination, electromyography, and exclusion of 'ALS-mimics' (e.g. cervical spondylotic myelopathies, multifocal motor neuropathy, Kennedy's disease) by appropriate investigations. The pathological hallmarks comprise loss of motor neurones with intraneuronal ubiquitin-immunoreactive inclusions in upper motor neurones and TDP-43 immunoreactive inclusions in degenerating lower motor neurones. Signs of upper motor neurone and lower motor neurone damage not explained by any other disease process are suggestive of ALS. The management of ALS is supportive, palliative, and multidisciplinary. Non-invasive ventilation prolongs survival and improves quality of life. Riluzole is the only drug that has been shown to extend survival. PMID:19192301

Wijesekera, Lokesh C; Leigh, P Nigel

2009-01-01

201

Management of temporomandibular joint ankylosis type III: lateral arthroplasty as a treatment of choice.  

PubMed

Many surgical techniques for the management of temporomandibular joint (TMJ) ankylosis have been described in the literature. The purpose of this study was to report our experience using a lateral arthroplasty technique in the management of type III ankylosis. The records of 15 patients treated for TMJ ankylosis at our institution between 2007 and 2011 were reviewed. Pre- and postoperative information collected included age, gender, aetiology, ankylosis type/classification, existing facial asymmetry, maximum pre- and postoperative mouth opening, complications, and recurrence of ankylosis. The mean maximum inter-incisal opening in the preoperative period was 12.9 mm and in the postoperative period was 36.2mm. No major complication was observed in any patient. No recurrence was noted in any patient. Our working hypothesis was that for patients with ankylosis type III, the medially displaced condyle and disc can fulfil their role in mandibular function and growth after extirpation of the ankylozed mass. Although they are located in an awkward medial position, they should function exactly as they would after a properly treated, displaced condylar fracture. PMID:24100155

Singh, V; Bhagol, A; Dhingra, R; Kumar, P; Sharma, N; Singhal, R

2014-04-01

202

Lateral Thinking and Technology Education  

Microsoft Academic Search

The emergence of lateral thinking in recent years is a natural reaction to the enormous increase of information a human being is “bombarded” with, in the post industrial revolution era. Vertical thinking, with its sequential and fixed-order rules, which has been the foundation of traditional education, is increasingly being complemented by lateral thinking which aims at freeing the mind from

Shlomo Waks

1997-01-01

203

4, 317348, 2007 Lateral carbon  

E-print Network

BGD 4, 317­348, 2007 Lateral carbon exchange in a tidal mangrove creek S. Bouillon et al. Title mangrove creek (Ras Dege, Tanzania) S. Bouillon 1,2 , J. J. Middelburg 2 , F. Dehairs 1 , A. V. Borges 3, France 317 #12;BGD 4, 317­348, 2007 Lateral carbon exchange in a tidal mangrove creek S. Bouillon et al

Boyer, Edmond

204

[Multivariate prediction of breeding values for canine hip and elbow dysplasia as well as humeral osteochondrosis in the Bernese mountain dog].  

PubMed

The aim of this study was the multivariate prediction of breeding values for canine hip dysplasia (CHD), elbow dysplasia (ED) and humeral osteochondrosis (OCD) for Bernese mountain dogs of the Schweizer Sennenhund-Verein für Deutschland e. V. (SSV). For the analysis the pedigrees of eight generations and radiographic screening results of the birth cohorts from 1995-2008 were used. The number of dogs with scores for CHD was 5513, for ED 5175 and OCD 1240. Breeding values were multivariately predicted using a mixed linear model for CHD, ED and OCD as well as for the occurrence of a fragmented coronoid process of the medial ulna (FCP) and the ED-score without FCP. The pedigree breeding value (eRZWp) which is used as the selection criterion reached a reliability to predict the phenotype of the offspring at 2.8-2.9% for CHD, 2.9% for ED, 1.1% for ED without FCP, 1.8% for FCP and 0.8-1.3% for OCD. The reason for the low predictive value of the eRZW(P) is caused by the very high influence of the own performance of the animal and the very uniform distribution of contributions of the breeding values of the relatives.These results indicate that even a multivariate prediction of breeding values does not lead to a faster progress in breeding against CHD and ED, however, does allow breeding against OCD in the Bernese mountain dog. In comparison to phenotypic selection, there is some improvement in the selection response when using breeding values. Due to the general low predictive power of breeding values better approaches for selection of future breeding animals are urgently warranted to achieve improvements in breeding Bernese mountain dogs. PMID:23045807

Hartmann, Peter; Stock, Kathrin-Friederike; Distl, Ottmar

2012-01-01

205

Advantage of Minimally Invasive Lateral Approach Relative to Conventional Deltopectoral Approach for Treatment of Proximal Humerus Fractures  

PubMed Central

Background Despite the wide application of open reduction and internal fixation with locking plates for the treatment of proximal humeral fractures, the surgical invasive approach remains controversial. This study aimed to evaluate the pros and cons of the minimally invasive lateral approach for the treatment of proximal humeral fracture (PHF) in comparison with the deltopectoral approach. Material/Methods All patients who sustained a PHF and received open reduction and internal fixation (ORIF) surgery with locking plate through either minimally invasive subacromial approach or conventional deltopectoral approach between January 2008 and February 2012 were retrospectively analyzed. Patients were divided into the conventional group and min-group according to the surgical incision. Surgery-related information, postoperative radiography, complications, and shoulder functional measurement scores in a 2-year follow-up were collected and evaluated. Results Ninety-one patients meeting the inclusion criteria were included in this study. We observed a significant difference in both surgery time (81.8±18.3 vs. 91.0±18.4) (p=0.021) and blood loss (172±54.2 vs. 205±73.6) (p=0.016) between the min-group and conventional group. Compared to the conventional group, the min-group had significantly better Constant-Murley score and DASH score at early follow-up (p<0.05) and higher patients satisfaction rate (8.1±1.1 vs. 7.6±1.2) (p= 0.019). The multiple linear regression analysis indicated that age, PHF types, surgical groups, surgery time, and blood loss have significant effect on the activity of affected shoulder in both abduction and forward flexion (p<0.05) except for gender factor. While larger range of movement of the affected shoulder, mainly in the 2-part and 3-part fractures, was observed in the min-group, the conventional group obtained better movement in the 4-part fractures. Conclusions The minimally invasive lateral approach is the optimal alternative for the treatment of Neer’s type 2 and 3 proximal humerus fractures. PMID:25682320

Liu, Kuan; Liu, Peng-cheng; Liu, Run; Wu, Xing

2015-01-01

206

Lateral Transorbital Neuroendoscopic Approach to the Lateral Cavernous Sinus  

PubMed Central

Objective?To design and assess the quality of a novel lateral retrocanthal endoscopic approach to the lateral cavernous sinus. Design?Computer modeling software was used to optimize the geometry of the surgical pathway, which was confirmed on cadaver specimens. We calculated trajectories and surgically accessible areas to the middle fossa while applying a constraint on the amount of soft tissue retraction. Setting?Virtual computer model to simulate the surgical approach and cadaver laboratory. Participants?The authors. Main Outcome Measures?Adequate surgical access to the lateral cavernous sinus and adjacent regions as determined by operations on the cadaver specimens. Additionally, geometric limitations were imposed as determined by the model so that retraction on soft tissue structures was maintained at a clinically safe distance. Results?Our calculations revealed adequate access to the lateral cavernous sinus, Meckel cave, orbital apex, and middle fossa floor. Cadaveric testing revealed sufficient access to these areas using <10?mm of orbital retraction. Conclusions?Our study validates not only the use of computer simulation to plan operative approaches but the feasibility of the lateral retrocanthal approach to the lateral cavernous sinus. PMID:24498584

Bly, Randall A.; Ramakrishna, Rohan; Ferreira, Manuel; Moe, Kris S.

2013-01-01

207

[Osteotomy for approaches to the knee joint. Tibial tubercle, lateral epicondyle of the femur and head of the fibula].  

PubMed

The present article summarizes the different osteotomy techniques for an extension of standard surgical approaches to the knee joint in selected patients. The aim is to achieve satisfactory exposure and reduce potential postoperative complications compared to alternative techniques, such as the V-Y plasty or the quadriceps snip procedures. Osteotomy of the tibial tubercle is a reasonable extension of the anteromedial or the anterolateral surgical approach in selected patients undergoing revision total knee replacement. This osteotomy will provide excellent surgical exposure of the knee without the risk of avulsion of the patellar tendon and will preserve the blood supply of the patella and the surrounding soft tissue. Moreover, functional clinical outcome will be improved by minimizing damage to the extensor mechanism. Osteotomy of the lateral femoral condyle gives excellent exposure of the posterolateral aspect of the knee joint which might be necessary in some patients with fractures of the posterolateral tibial plateau as well as patients undergoing open allograft transplantation of the lateral meniscus. An alternative option for an extended exposure to the posterolateral knee joint is accomplished by osteotomy or partial resection of the fibular head which is also described as having good clinical results and a low complication rate. PMID:23632649

Lorbach, O; Anagnostakos, K; Kohn, D

2013-05-01

208

Lateral collateral ligament (LCL) injury  

MedlinePLUS

LCL injury; Knee injury - lateral collateral ligament (LCL) ... ligament helps keep the outer side of the knee joint stable. ... by pressure or an injury that pushes the knee joint from the inside, which results in stress ...

209

Hyperaldosteronism: diagnosis, lateralization, and treatment.  

PubMed

Primary hyperaldosteronism is an important and commonly unrecognized secondary cause of hypertension. This article provides an overview of the current literature with respect to screening, diagnosis, and lateralization. Selection and outcomes of medical and surgical treatment are discussed. PMID:24857581

Harvey, Adrian M

2014-06-01

210

Bilateral Multiple Level Lateral Meningocoele  

PubMed Central

Lateral meningocoele is a very rare disorder characterized by extensions of the dura and arachnoid through an enlarged neural foramen. We report a case of a 23-year-old female with deformity of spine who presented with low back pain and no neurological deficits. A whole spine magnetic resonance imaging showed multiple well-defined cystic masses involving dorsal, lumbar, and sacral spinal levels bilaterally, with dural ectasia and neural foraminal widening suggestive of bilateral multiple level lateral meningocoele. The patient is being managed conservatively and is on regular follow-up. PMID:23607071

Kumar, B. E. Panil; Hegde, Kishor V.; Kumari, G. Lalitha; Agrawal, Amit

2013-01-01

211

Lateral Diffusion in an Archipelago  

PubMed Central

Lateral diffusion of molecules in lipid bilayer membranes can be hindered by the presence of impermeable domains of gel-phase lipid or of proteins. Effective-medium theory and percolation theory are used to evaluate the effective lateral diffusion constant as a function of the area fraction of fluid-phase lipid and the permeability of the obstructions to the diffusing species. Applications include the estimation of the minimum fraction of fluid lipid needed for bacterial growth, and the enhancement of diffusion-controlled reactions by the channeling effect of solid patches of lipid. PMID:7052153

Saxton, Michael J.

1982-01-01

212

Borehole optical lateral displacement sensor  

DOEpatents

There is provided by this invention an optical displacement sensor that utilizes a reflective target connected to a surface to be monitored to reflect light from a light source such that the reflected light is received by a photoelectric transducer. The electric signal from the photoelectric transducer is then imputed into electronic circuitry to generate an electronic image of the target. The target`s image is monitored to determine the quantity and direction of any lateral displacement in the target`s image which represents lateral displacement in the surface being monitored. 4 figs.

Lewis, R.E.

1998-10-20

213

Intra-articular synovial lipoma of the knee joint (located in the lateral recess): a case report and review of the literature.  

PubMed

This report describes a rare intra-articular synovial lipoma of the knee joint which developed in a 66-year-old female. The patient suffered from sudden knee pain and a catching or slight interruption of normal motion of the left knee and then noticed the tumor. The tumor was located in the lateral recess of the knee joint and showed a signal intensity similar to subcutaneous fat on T1 and T2()-weighted magnetic resonance images. The arthroscopy revealed a smooth, globular, yellowish, encapsulated tumor extending into the lateral recess from the surface of the lateral condyle and the tumor was totally excised under arthroscopic guidance. Histologic examination of the specimen revealed a tumor composed of mature adipose cells covered by a thin fibrous layer of varying thickness and normal synovial lining cells. The diagnosis was intra-articular synovial lipoma. Intra-articular synovial lipomas should be distinguished from other similar lipomatoid conditions such as Hoffa disease and villous lipomatous proliferation of the synovial membrane (lipoma arborescens). Intra-articular synovial lipoma should be considered in the differential diagnoses when examining a patient with sudden knee pain, and a catching or locking knee. PMID:17127064

Hirano, Kenichi; Deguchi, Masao; Kanamono, Toshihisa

2007-01-01

214

Observation of lateral vehicle dynamics  

Microsoft Academic Search

By observation of lateral vehicle dynamics the detection of critical driving situations is made possible, as well as the estimation of adhesion characteristics during cornering. This paper presents a comparison of a linear and a nonlinear observer for the vehicle and tyre side-slip angles. The modelling, especially the model reduction and simplification, is shown.

U. Kiencke; A. Daiß

1997-01-01

215

Nuclear fuel rack lateral restraint  

Microsoft Academic Search

A lateral restraint device for nuclear fuel racks which can accommodate differential thermal expansion between the racks and a containing enclosure is described. The restraint includes a piston, movable within a cylinder, joined to one or more support pads which contact the wall of the enclosure. A spring is also provided within the cylinder to act upon the piston. The

D. J. Kaminski; C. H. Boyd

1979-01-01

216

Lateral Preferences in the Monkey  

Microsoft Academic Search

THERE is general agreement that the majority of monkeys show lateral preferences on a particular task1-6, about as many animals showing a strong preference for the left hand as for the right. However, Ettlinger5 reported that significantly more monkeys preferred to use the left hand than the right on their first discrimination task (irrespective of the task being visual or

G. Ettlinger; A. Moffett

1964-01-01

217

Hemangiopericitoma óseo de localización humeral  

Microsoft Academic Search

Bone hemangiopericytoma located in the humerus SUMMARY Background: Hemangiopericytoma is a rare malignant vascular tumor of pericyte origin, accounting for 0.1% of all malignant bone tumors and only 0.08% of total primary bone tumors. Material and Method: We describe a case of intraosseus hemangiopericytoma in the right hume- rus of a 69 year old female, diagnosed by aspiration cytology and

Antonio Urban Ramón; Adriá Jovani Meseguer; Olga García Vidal; Isabel Antón Antón; Concepción Murcia Mesa

218

Lateral dampers for thrust bearings  

NASA Technical Reports Server (NTRS)

The development of lateral damping schemes for thrust bearings was examined, ranking their applicability to various engine classes, selecting the best concept for each engine class and performing an in-depth evaluation. Five major engine classes were considered: large transport, military, small general aviation, turboshaft, and non-manrated. Damper concepts developed for evaluation were: curved beam, constrained and unconstrained elastomer, hybrid boost bearing, hydraulic thrust piston, conical squeeze film, and rolling element thrust face.

Hibner, D. H.; Szafir, D. R.

1985-01-01

219

Detecting lateral genetic material transfer  

E-print Network

The bioinformatical methods to detect lateral gene transfer events are mainly based on functional coding DNA characteristics. In this paper, we propose the use of DNA traits not depending on protein coding requirements. We introduce several semilocal variables that depend on DNA primary sequence and that reflect thermodynamic as well as physico-chemical magnitudes that are able to tell apart the genome of different organisms. After combining these variables in a neural classificator, we obtain results whose power of resolution go as far as to detect the exchange of genomic material between bacteria that are phylogenetically close.

Calderón, C; Mireles, V; Miramontes, P

2012-01-01

220

Clinical Neurogenetics: Amyotrophic Lateral Sclerosis  

PubMed Central

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease, about which our understanding is expanding rapidly as its genetic causes are uncovered. The pace of new gene discovery over the last 5 years has accelerated, providing new insights into the pathogenesis of disease and highlighting biological pathways for target for therapeutic development. This article reviews our current understanding of the heritability of ALS, provides an overview of each of the major ALS genes, highlighting their phenotypic characteristics and frequencies as a guide for clinicians evaluating patients with ALS. PMID:24176417

Harms, Matthew B.; Baloh, Robert H.

2013-01-01

221

Lateral genetic transfer: open issues  

PubMed Central

Lateral genetic transfer (LGT) is an important adaptive force in evolution, contributing to metabolic, physiological and ecological innovation in most prokaryotes and some eukaryotes. Genomic sequences and other data have begun to illuminate the processes, mechanisms, quantitative extent and impact of LGT in diverse organisms, populations, taxa and environments; deep questions are being posed, and the provisional answers sometimes challenge existing paradigms. At the same time, there is an enhanced appreciation of the imperfections, biases and blind spots in the data and in analytical approaches. Here we identify and consider significant open questions concerning the role of LGT in genome evolution. PMID:19571244

Ragan, Mark A.; Beiko, Robert G.

2009-01-01

222

Lateralization of aggression in fish.  

PubMed

Recent research has suggested that lateralization of aggressive behaviors could follow an homogeneous pattern among all vertebrates. A left eye/right hemisphere dominance in eliciting aggressive responses has been demonstrated for all groups of tetrapods but teleost fish for which data is lacking. Here we studied differential eye use during aggressive interactions in three species of teleosts: Gambusia holbrooki, Xenotoca eiseni and Betta splendens. In the first experiment we checked for lateralization in the use of the eyes while the subject was attacking its own mirror image. In order to confirm the results, other tests were performed on two species and eye preference was scored during attacks or displays directed toward a live rival. All three species showed a marked preference for using the right eye when attacking a mirror image or a live rival. Thus, the direction of asymmetry in fish appears the opposite to that shown by all the other groups of vertebrates. Hypotheses on the origin of the difference are discussed. PMID:12742249

Bisazza, Angelo; de Santi, Andrea

2003-05-15

223

Managing Complications of Diabetes in Later Life  

MedlinePLUS

... Download PDF Managing Complications of Diabetes in Later Life Download Join our e-newsletter! Resources Managing Complications of Diabetes in Later Life Tools and Tips Printer-friendly PDF Click here ...

224

49 CFR 230.105 - Lateral motion.  

Code of Federal Regulations, 2010 CFR

...ADMINISTRATION, DEPARTMENT OF TRANSPORTATION STEAM LOCOMOTIVE INSPECTION AND MAINTENANCE STANDARDS Steam Locomotives and Tenders Running Gear § 230.105 Lateral motion. (a) Condemning limits. The total lateral motion or play between...

2010-10-01

225

Kepler: 400 years later Jonas Karlsson  

E-print Network

Kepler: 400 years later #12;Outline Kepler's laws Proof that closed orbits are ellipses The hydrogen atom Geodesic ow and the Kepler manifold Jonas Karlsson Kepler: 400 years later #12;Kepler's laws Johannes Kepler (1571 - 1630) Jonas Karlsson Kepler: 400 years later #12;Kepler's laws First law (1609

Weinberger, Hans

226

Auxin Transport Promotes Arabidopsis Lateral Root Initiation  

Microsoft Academic Search

Lateral root development in Arabidopsis provides a model for the study of hormonal signals that regulate postembry- onic organogenesis in higher plants. Lateral roots originate from pairs of pericycle cells, in several cell files positioned opposite the xylem pole, that initiate a series of asymmetric, transverse divisions. The auxin transport inhibitor N -1-naph- thylphthalamic acid (NPA) arrests lateral root development

Ilda Casimiro; Alan Marchant; Rishikesh P. Bhalerao; Tom Beeckman; Sandra Dhooge; Ranjan Swarup; Neil Graham; Dirk Inzé; Goran Sandberg; Pedro J. Casero; Malcolm Bennett

2001-01-01

227

49 CFR 229.63 - Lateral motion.  

Code of Federal Regulations, 2010 CFR

...2010-10-01 2010-10-01 false Lateral motion. 229.63 Section 229.63...Requirements Suspension System § 229.63 Lateral motion. (a) Except as provided in paragraph (b), the total uncontrolled lateral motion between the hubs of the...

2010-10-01

228

CYSTS OF THE LATERAL MENISCUS  

PubMed Central

Accurate diagnosis and management of knee pain with or without mechanical symptoms challenges the physical therapist's clinical reasoning skills. Meniscal cysts are one relatively rare disorder of the knee that can cause both pain and mechanical symptoms and are frequently associated with a meniscal tear. In patients with suspected meniscal cysts, systematic differential diagnosis and sound clinical reasoning encourages appropriate integration of the clinical examination with diagnostic imaging. These case reports describe two different presentations of lateral parameniscal cysts where integration of the clinical examination with appropriate imaging allowed the physical therapist to provide a timely and appropriate intervention. In both cases, the diagnostic process is described along with the subsequent interventions that lead to positive outcomes. Level of Evidence: 5 (Case Report) PMID:23772349

Westrick, Richard B.; Fogarty, Brian T.

2013-01-01

229

Biomarkers in amyotrophic lateral sclerosis.  

PubMed

Amyotrophic lateral sclerosis (ALS; motor neuron disease) is a relentlessly progressive disorder. After half a century of trials, only one drug with modest disease-modifying potency--riluzole--has been developed. The diagnosis of this disorder is still clinical and there is a pronounced delay between the onset of symptoms and diagnosis, possibly beyond the therapeutic window. Bedside quantification of the involvement of the corticospinal tract and extramotor areas is inadequate and functional rating scales, forced vital capacity, and patient survival have been the measures of therapeutic response so far. Potential biomarkers that are sensitive to the progression of disease, which might enhance the diagnostic algorithm and provide new drug targets, are now being identified from analysis of the blood and cerebrospinal fluid, as well as from neuroimaging and neurophysiology studies. In combination, these biomarkers might be sensitive to early therapeutic effects and would reduce our reliance on animal models, which have uncertain relevance to sporadic ALS in human beings. Such biomarkers might also resolve complexities of phenotypic heterogeneity in clinical trials. In this Review, we discuss the development of biomarkers in ALS and consider potential future directions for research. PMID:19081518

Turner, Martin R; Kiernan, Matthew C; Leigh, P Nigel; Talbot, Kevin

2009-01-01

230

Wilson's disease, 100 years later….  

PubMed

Texts published, in 1912, 100 years ago, by Sir K. Wilson on his eponymous disease in Brain, The Lancet and La Revue Neurologique highlight the relevance of his descriptions in the light of the current knowledge. Wilson's invocation of an "unknown toxin" appears today as a prophetic intuition as the presence of excess copper in the liver was mentioned for the first time a year later whereas the role of copper in this disease was not described until 1929. Progress has been made to better understand the physiology of Wilson's disease (WD). The ATP7B gene implicated in WD is located on chromosome 13 and more than 500 mutations and 100 polymorphisms have been to date identified. The phenotypic expression is highly variable, even within a family. This can partly be explained by environmental factors as nutrition. Modulator genes are also involved in the phenotypic expression of the disease. Most of symptoms observed in WD have already been described in detail by Wilson in 1912, but subsequent progress was made over the following 100 years, helping the physician diagnose WD. Hepatic and neurological symptoms are the most frequent expressions of the disease. Other extrahepatic features include renal manifestations, osteoarticular disorders, myocardial abnormalities, endocrine disturbances, realizing a multisystemic disease. The diagnosis of the disease is based on a combination of clinical symptoms, biological, radiological and genetic data and new tools (Brain MRI, relative exchangeable copper…) allow reducing delay to diagnosis. Therapeutic findings have also changed the disease prognosis. Treatment is based on the use of copper chelators to promote copper excretion from the body (D-penicillamine and Triethylenetetramine) and zinc salts to reduce copper absorption. Tetratiomolybdate appears to be a promising treatment. While significant progress has been made during this century, many physiological aspects of this disease remain unknown and require further research to find answers in the next 100 years. PMID:24119853

Trocello, J-M; Broussolle, E; Girardot-Tinant, N; Pelosse, M; Lachaux, A; Lloyd, C; Woimant, F

2013-12-01

231

Retroviruses and amyotrophic lateral sclerosis  

PubMed Central

Amyotrophic lateral sclerosis (ALS) is a progressive, invariably fatal neurologic disorder resulting from upper and lower motor neuron degeneration, which typically develops during the sixth or seventh decade of life, and is diagnosed based on standard clinical criteria. Its underlying cause remains undetermined. The disease may occur with increased frequency within certain families, often in association with specific genomic mutations, while some sporadic cases have been linked to environmental toxins or trauma. Another possibility, first proposed in the 1970s, is that retroviruses play a role in pathogenesis. In this paper, we review the published literature for evidence that ALS is associated either with infection by an exogenous retrovirus or with the expression of human endogenous retroviral (HERV) sequences in cells of the central nervous system. A small percentage of persons infected with the human immunodeficiency virus-1 (HIV-1) or human T cell leukemia virus-1 (HTLV-1) develop ALS-like syndromes. While HTLV-1 associated ALS-like syndrome has several features that may distinguish it from classical ALS, HIV-infected patients may develop neurological manifestations that resemble classical ALS although it occurs at a younger age and they may show a dramatic improvement following the initiation of antiretroviral therapy. However, most patients with probable or definite ALS show no evidence of HIV-1 or HTLV-1 infection. In contrast, recent reports have shown a stronger association with HERV, as analysis of serum samples, and postmortem brain tissue from a number of patients with a classical ALS has revealed significantly increased expression of HERV-K, compared to controls. These findings suggest that endogenous retroviral elements are involved in the pathophysiology of ALS, but there is no evidence that they are the primary cause of the syndrome. PMID:23707220

Alfahad, Tariq; Nath, Avindra

2013-01-01

232

Retroviruses and amyotrophic lateral sclerosis.  

PubMed

Amyotrophic lateral sclerosis (ALS) is a progressive, invariably fatal neurologic disorder resulting from upper and lower motor neuron degeneration, which typically develops during the sixth or seventh decade of life, and is diagnosed based on standard clinical criteria. Its underlying cause remains undetermined. The disease may occur with increased frequency within certain families, often in association with specific genomic mutations, while some sporadic cases have been linked to environmental toxins or trauma. Another possibility, first proposed in the 1970s, is that retroviruses play a role in pathogenesis. In this paper, we review the published literature for evidence that ALS is associated either with infection by an exogenous retrovirus or with the expression of human endogenous retroviral (HERV) sequences in cells of the central nervous system. A small percentage of persons infected with the human immunodeficiency virus-1 (HIV-1) or human T cell leukemia virus-1 (HTLV-1) develop ALS-like syndromes. While HTLV-1 associated ALS-like syndrome has several features that may distinguish it from classical ALS, HIV-infected patients may develop neurological manifestations that resemble classical ALS although it occurs at a younger age and they may show a dramatic improvement following the initiation of antiretroviral therapy. However, most patients with probable or definite ALS show no evidence of HIV-1 or HTLV-1 infection. In contrast, recent reports have shown a stronger association with HERV, as analysis of serum samples, and postmortem brain tissue from a number of patients with a classical ALS has revealed significantly increased expression of HERV-K, compared to controls. These findings suggest that endogenous retroviral elements are involved in the pathophysiology of ALS, but there is no evidence that they are the primary cause of the syndrome. PMID:23707220

Alfahad, Tariq; Nath, Avindra

2013-08-01

233

Artificial lateral line canal for hydrodynamic detection  

NASA Astrophysics Data System (ADS)

Fish use their lateral line system to detect minute water motions. The lateral line consists of superficial neuromasts and canal neuromasts. The response properties of canal neuromasts differ from those of superficial ones. Here, we report the design, fabrication, and characterization of an artificial lateral line canal system. The characterization was done under various fluid conditions, including dipolar excitation and turbulent flow. The experimental results with dipole excitation match well with a mathematical model. Canal sensors also demonstrate significantly better noise immunity compared with superficial ones. Canal-type artificial lateral lines may become important for underwater flow sensing.

Yang, Yingchen; Klein, Adrian; Bleckmann, Horst; Liu, Chang

2011-07-01

234

Simultaneous medial and lateral patellofemoral ligament reconstruction for combined medial and lateral patellar subluxation.  

PubMed

Medial patellar subluxation (MPS) is a disabling, often iatrogenic patellar instability due to previous lateral release for patellar instability. Lateral release destabilizes the patella on the lateral side, worsening the initial lateral instability and causing MPS. MPS is poorly recognized and may range from subluxation to true dislocation. This report describes a technique developed in response to episodes of medial and lateral patellar subluxation after failed lateral release for patellar instability. The technique uses a graft that extends from the medial patellofemoral ligament origin through the quadriceps tendon to the lateral epicondyle, thereby reconstructing both the medial and lateral patellofemoral ligaments, as well as providing simultaneous stability to both the medial and lateral sides of the patella. PMID:24904765

Saper, Michael G; Shneider, David A

2014-04-01

235

Lateral patellar retinaculum reconstruction for medial patellar instability following lateral retinacular release: a case report.  

PubMed

Lateral retinacular release is still being performed in patients with recurrent patellar dislocation as an additional procedure with distal realignment or medial patellofemoral ligament (MPFL) reconstruction. However, consensus remains lacking regarding suitable indications for lateral retinacular release. A 20-year-old woman presented with patellar instability in both medial and lateral directions after undergoing lateral retinacular release with MPFL reconstruction. She displayed inherent systemic joint laxity meeting all seven Carter-Wilkinson criteria. Simultaneous MPFL revision and lateral retinaculum reconstruction successfully improved patellar instability in both directions. This case provides an example of iatrogenic medial patellar instability after failed lateral retinacular release. PMID:23688523

Udagawa, Kazuhiko; Niki, Yasuo; Matsumoto, Hiroaki; Matsumoto, Hideo; Enomoto, Hiroyuki; Toyama, Yoshiaki; Suda, Yasunori

2014-01-01

236

Usefulness of a Lateral Thoracodorsal Flap after Breast Conserving Surgery in Laterally Located Breast Cancer  

PubMed Central

Background Breast-conserving surgery is widely accepted as an appropriate method in breast cancer, and the lateral thoracodorsal flap provides a simple, reliable technique, especially when a mass is located in the lateral breast. This study describes the usefulness of a lateral thoracodorsal flap after breast conserving surgery in laterally located breast cancer. Methods From September 2008 to February 2013, a lateral thoracodorsal flap was used in 20 patients with laterally located breast cancer treated at our institution. The technique involves a local medially based, wedge shaped, fasciocutaneous transposition flap from the lateral region of the thoracic area. Overall satisfaction and aesthetic satisfaction surveys were conducted with the patients during a 6-month postoperative follow-up period. Aesthetic results in terms of breast shape and symmetry were evaluated by plastic surgeons. Results The average specimen weight was 76.8 g. The locations of the masses were the upper lateral quadrant (n=15), the lower lateral quadrant (n=2), and the central lateral area (n=3). Complications developed in four of the cases, partial flap necrosis in one, wound dehiscence in one, and fat necrosis in two. The majority of the patients were satisfied with their cosmetic outcomes. Conclusions Partial breast reconstruction using a lateral thoracodorsal flap is well matched with breast color and texture, and the surgery is less aggressive than other techniques with few complications. Therefore, the lateral thoracodorsal flap can be a useful, reliable technique in correcting breast deformity after breast conserving surgery, especially in laterally located breast cancer. PMID:23898433

Ryu, Dong Wan; Lee, Jeong Woo; Choi, Kang Young; Chung, Ho Yun; Cho, Byung Chae; Park, Ho Yong; Byun, Jin Suk

2013-01-01

237

Arthroscopic Centralization of an Extruded Lateral Meniscus  

PubMed Central

Extrusion of the lateral meniscus has been reported after posterior root tear or radial tear, partial meniscectomy, and meniscoplasty of discoid meniscus. It has also been shown to be associated with the development of osteoarthritis. This technical note describes a new arthroscopic technique to centralize and stabilize the mid body of the lateral meniscus to restore and maintain the lateral meniscus function by repairing/preventing extrusion of the meniscus. A JuggerKnot Soft Anchor (Biomet, Warsaw, IN), loaded with a MaxBraid suture (Biomet), was placed on the lateral edge of the lateral tibial plateau, just anterior to the popliteal hiatus, through a midlateral portal. A Micro Suture Lasso Small Curve with Nitinol Wire Loop (Arthrex, Naples, FL) was used to pass 2 limbs of the MaxBraid suture through the meniscus at the margin between the meniscus and the capsule. Another anchor was inserted on the lateral edge of the lateral tibial plateau, 1 cm anterior to the first anchor, and the same procedure was repeated. The sutures were then tied by use of a self-locking sliding knot, achieving centralization and secure stabilization of the lateral meniscus. PMID:23766997

Koga, Hideyuki; Muneta, Takeshi; Yagishita, Kazuyoshi; Watanabe, Toshifumi; Mochizuki, Tomoyuki; Horie, Masafumi; Nakamura, Tomomasa; Okawa, Atsushi; Sekiya, Ichiro

2012-01-01

238

Arthroscopic centralization of an extruded lateral meniscus.  

PubMed

Extrusion of the lateral meniscus has been reported after posterior root tear or radial tear, partial meniscectomy, and meniscoplasty of discoid meniscus. It has also been shown to be associated with the development of osteoarthritis. This technical note describes a new arthroscopic technique to centralize and stabilize the mid body of the lateral meniscus to restore and maintain the lateral meniscus function by repairing/preventing extrusion of the meniscus. A JuggerKnot Soft Anchor (Biomet, Warsaw, IN), loaded with a MaxBraid suture (Biomet), was placed on the lateral edge of the lateral tibial plateau, just anterior to the popliteal hiatus, through a midlateral portal. A Micro Suture Lasso Small Curve with Nitinol Wire Loop (Arthrex, Naples, FL) was used to pass 2 limbs of the MaxBraid suture through the meniscus at the margin between the meniscus and the capsule. Another anchor was inserted on the lateral edge of the lateral tibial plateau, 1 cm anterior to the first anchor, and the same procedure was repeated. The sutures were then tied by use of a self-locking sliding knot, achieving centralization and secure stabilization of the lateral meniscus. PMID:23766997

Koga, Hideyuki; Muneta, Takeshi; Yagishita, Kazuyoshi; Watanabe, Toshifumi; Mochizuki, Tomoyuki; Horie, Masafumi; Nakamura, Tomomasa; Okawa, Atsushi; Sekiya, Ichiro

2012-12-01

239

Lateral displacement and rotational displacement sensor  

DOEpatents

A position measuring sensor formed from opposing sets of capacitor plates measures both rotational displacement and lateral displacement from the changes in capacitances as overlapping areas of capacitors change. Capacitances are measured by a measuring circuit. The measured capacitances are provided to a calculating circuit that performs calculations to obtain angular and lateral displacement from the capacitances measured by the measuring circuit.

Duden, Thomas

2014-04-22

240

Monitoring System Design for Lateral Vehicle Motion  

Microsoft Academic Search

Monitoring of lateral vehicle motion is very useful in many active safety applications such as yaw stability control and rollover prevention. Lateral velocity and sideslip angle are regarded as the most important motion variables. However, it is not feasible during vehicle operation to directly measure them due to the high cost of sensors, limitations to sensor technology, etc. Therefore, the

Sangoh Han; Kunsoo Huh

2011-01-01

241

Anatomy of the Lateral Ankle Ligaments  

Microsoft Academic Search

The anatomy of the lateral ankle ligaments that is fre quently described in articles and book chapters often lacks the precision of orientation and attachment points. We believe a knowledge of this precise anatomy is im portant to better reconstruct or repair lateral ligaments. We dissected cadaveric ankles free of skin and soft tis sue and made the following measurements:

Robert T. Burks; James Morgan

1994-01-01

242

Later Life Social Engagement and Health  

Microsoft Academic Search

The topic of later life social engagement is of growing importance worldwide given the confluence of large demographic, economic, and sociocultural trends. However, empirical research in this area faces some serious theoretical and methodological limitations. The purpose of this study was to address these limitations by: (1) examining the later life mental and physical health effects of five social roles,

Manacy Pai

2008-01-01

243

Laterality and Dyslexia: A Critical View.  

ERIC Educational Resources Information Center

Research is reviewed concerning the current state of knowledge about normal hemispheric specialization; distinctions among such terms as dominance, laterality, and lateralization; and models of abnormal cerebral organization in dyslexic children. The question of dyslexic subtypes is undertaken along such dimensions as handedness, eyedness, and…

Hiscock, Merrill; Kinsbourne, Marcel

1982-01-01

244

Lateral transfer: a source of additional overpressure?  

Microsoft Academic Search

Overpressure generated by disequilibrium compaction can be enhanced at structural crests by the lateral transfer of fluids from deep, overpressured parts of a basin along laterally extensive inclined aquifers. Fluid flow modelling shows that the effect of an inclined aquifer ranges from being minimal to being a significant contributor (>10 MPa) to crestal pore pressures depending on the style of

G. S. Yardley; R. E. Swarbrick

2000-01-01

245

Aeromonas hydrophila Lateral Flagellar Gene Transcriptional Hierarchy  

PubMed Central

Aeromonas hydrophila AH-3 lateral flagella are not assembled when bacteria grow in liquid media; however, lateral flagellar genes are transcribed. Our results indicate that A. hydrophila lateral flagellar genes are transcribed at three levels (class I to III genes) and share some similarities with, but have many important differences from, genes of Vibrio parahaemolyticus. A. hydrophila lateral flagellum class I gene transcription is ?70 dependent, which is consistent with the fact that lateral flagellum is constitutively transcribed, in contrast to the characteristics of V. parahaemolyticus. The fact that multiple genes are included in class I highlights that lateral flagellar genes are less hierarchically transcribed than polar flagellum genes. The A. hydrophila lafK-fliEJL gene cluster (where the subscript L distinguishes genes for lateral flagella from those for polar flagella) is exclusively from class I and is in V. parahaemolyticus class I and II. Furthermore, the A. hydrophila flgAMNL cluster is not transcribed from the ?54/LafK-dependent promoter and does not contain class II genes. Here, we propose a gene transcriptional hierarchy for the A. hydrophila lateral flagella. PMID:23335410

Wilhelms, Markus; Gonzalez, Victor; Merino, Susana

2013-01-01

246

Pediatric laparoscopic splenectomy using the lateral approach  

Microsoft Academic Search

Laparoscopic splenectomy in children has been shown to be safe, to reduce postoperative pain and hospital stay, and to accelerate return to full activities. We describe our experience with a four-port “lateral” approach in 18 patients. Patients were placed in the lateral decubitus position and the table was flexed to separate the left subcostal margin and iliac crest. The camera

P. G. Fitzgerald; J. C. Langer; B. H. Cameron; A. E. Park; M. J. Marcaccio; J. M. Walton; M. A. Skinner

1996-01-01

247

[Lateral ligament injuries of the ankle joint].  

PubMed

Lateral ligament injuries are the most common sports injury and have a high incidence even in non-sportive activities. Although lateral ligament injuries are very common there is still a controversial debate on the best management. The diagnosis is based on clinical examination and X-ray images help to rule out fractures. Further imaging, especially magnetic resonance imaging (MRI) is used to diagnose associated injuries. According to the recommendations of the various scientific societies the primary therapy of lateral ligament injuries is conservative. Chronic ankle instability develops in 10-20 % of patients and the instability can be a result of sensomotoric deficits or insufficient healing of the lateral ligament complex. If the patient does not respond to an intensive rehabilitation program an operative reconstruction of the lateral ligaments has to be considered. Most of the procedures currently performed are anatomical reconstructions due to better long-term results compared to tenodesis procedures. PMID:23943058

Walther, M; Kriegelstein, S; Altenberger, S; Volkering, C; Röser, A; Wölfel, R

2013-09-01

248

Vannevar Bush: Fifty Years Later  

NASA Astrophysics Data System (ADS)

It is ironic that the 50th anniversary year of Vannevar Bush's Report to President Truman entitled "Science the Endless Frontier", which put into motion the eminently successful current system of education of scientists in this country occurs at a time when serious questions are being asked about the usefulness of that very system. Bush viewed his proposal to establish a national research foundation (later to be called the National Science Foundation) as a "social compact." Judgment of scientific merit would be delegated to expert peers in return for scientific progress, which would ultimately benefit the nation in terms of scientific needs--military security, economic productivity, and enhanced quality of life. Bush wanted the funding of basic research intertwined with training, and preferred to use universities for this purpose rather than industrial or national labs. Bush viewed college and university scientists as teachers and investigators. He believed university-based research would uniquely encourage and engage the next generation of scientists as no other institutional arrangement could. Bush did not trust industry's commitment to basic research, an instinct that proved prophetic. The academic reserve of scientists (PhD's in training and postdoctoral students) that existed before World War II, and upon which the United States could draw for its needs, which were primarily associated with defense efforts, was probably one of the defining factors in Bush's suggested strategy. Currently, that reserve of talent has gotten so large that it is the obvious throttle in the pipeline slowing the continued development of the university research enterprise. Since 1977, the rate at which we have trained new scientists exceeds an average of 4% annually. Since 1987, the "science work force"--PhD's--has grown at three times the rate of the general labor supply. Temporary positions for postdoctoral scientists have grown even faster (over 5% per year since 1989). To compound the problem, the 1990 Immigration Reform Act resulted in a tripling of job-based visas, with scientists representing nearly one-third of the total. In 1979, two of every three postdoctoral scientists were U.S.-born; in 1992, the ratio was about one to one. Over that period, the cohort of postdoctoral scientists grew from 18,000 to 33,000. Adding to the coincidence of events that have compounded one another is the admission of 20,000 Chinese scientists in a ten-year period, the sudden and unexpected availability of Russian scientists, the elimination of many industrial laboratories as a result of downsizing, changes in the mandatory retirement age for faculty, and the disappearance of the Cold War, which all but eliminated the need for scientists for national security purposes. Is it any wonder that postdoctoral scientists have been called the migrant workers of today's high-tech society? What once was a reservoir of enthusiastic talent is becoming a dumping ground for credentialed and capable scientists exiled from the main stream of their disciplines. From a broader point of view, the problems facing U.S. science are those of our society: an imposing deficit that is shrinking discretionary funding; the end of the Cold War, which has refocused spending for national security; and a robust science work force that can no longer expand. The business world's response to these societal problems is, basically, downsizing, which often means the elimination of large segments of the work force, usually at the middle-management level. The initial academic response to these same problems is either to insist on more resources being made available, usually through federal agencies, in an attempt to maintain the status quo, or to engage in some form of "academic birth control." The former strategy is unrealistic because it just perpetuates the problem; there will never be enough research professorships in the academic world for every aspiring PhD produced in a discipline. The latter strategy will invariably decrease the flow of truly n

Lagowski, J. J.

1995-12-01

249

Function of lateral line canal morphology.  

PubMed

Fish perceive water motions and pressure gradients with their lateral line. Lateral line information is used for prey detection, spatial orientation, predator avoidance, schooling behavior, intraspecific communication and station holding. The lateral line of most fishes consists of superficial neuromasts (SNs) and canal neuromasts (CNs). The distribution of SNs and CNs shows a high degree of variation among fishes. Researchers have speculated for decades about the functional significance of this diversity, often without any conclusive answers. Klein et al. (2013) examined how tubules, pore number and pore patterns affect the filter properties of lateral line canals in a marine teleost, the black prickleback (Xiphister atropurpureus). A preliminary mathematical model was formulated and biomimetic sensors were built. For the present study the mathematical model was extended to understand the major underlying principle of how canal dimensions influence the filter properties of the lateral line. Both the extended mathematical model and the sensor experiments show that the number and distribution of pores determine the spatial filter properties of the lateral line. In an environment with little hydrodynamic noise, simple and complex lateral line canals have comparable response properties. However, if exposed to highly turbulent conditions, canals with numerous widely spaced pores increase the signal to noise ratio significantly. PMID:24920149

Klein, Adrian; Bleckmann, Horst

2015-01-01

250

Laterality effects in cued auditory asymmetries.  

PubMed

The effect of cued attention on perceptual asymmetries was investigated with normal adults who differed in their lateral preference. Specifically, 15 right lateralized and a like number of mixed/left subjects were isolated on the basis of their lateral preference for visual guided motor activities. Learners' attention was directed to the left, right and both channels of dichotically presented verbal stimuli. Instructions to shift attention had little effect on the usual right-ear advantage for subjects who displayed a right of midline preference pattern. More bilateral subjects significantly improved their recognition of stimuli presented to the directed ear. PMID:7162591

Dean, R S; Hua, M S

1982-01-01

251

Rapid prototyping of lateral flow assays.  

PubMed

Principles and characteristics of lateral flow strip assays are reviewed. Recent technology developments permit the use of inexpensive electronic readers for interrogating lateral flow strip test results, thus avoiding the inevitable variation and subjectivity of visual inspection to assess the capture of reporter-labeled analyte on test lines of the strip. Protocols for developing lateral flow assays are described, including two specific case studies for assaying cotinine (a small-molecule metabolite of nicotine) in a competitive format, and assaying HIV antibodies in a sandwich-type assay format. PMID:19159100

Volkov, Alexander; Mauk, Michael; Corstjens, Paul; Niedbala, R Sam

2009-01-01

252

Surgical repair of ruptured lateral ankle ligaments  

Microsoft Academic Search

Fifty-two of 86 repaired lateral ankle ligaments were reevaluated 3 to 53 months after surgery. Ninety-eight percent were functionally stable. Mechanical stability was determined by talar tilt measurement on \\

Robert L. Brand; Myron D. F. Collins; Tom Templeton

1981-01-01

253

Septum formation of the lateral ventricles.  

PubMed

In an MRI study examining anomalies of the septum pellucidum in 505 cases, we detected bilateral septum formation of the lateral ventricles in a 17-month-old baby. In this study, we evaluate 505 (242 males and 263 females) patients referred to the Emaray Imaging Center, Ankara, Turkey with various prediagnoses. We specially selected all the cases from a non-psychotic population. We obtained MRI scans on a 1-Tesla imager (Picker International, Highland Heights, Ohio, USA), with slices of 5 and 6 mm thickness. In axial and coronal sections, we observed septum formation laterally between the anterior horn and the ventricular body of the lateral ventricles. Radio opaque septum formations started from the caudate nucleus and stretched to the genu of the corpus callosum. There was a second septum formation between the posterior horn and the ventricular body of the right lateral ventricle. It started from the caudate nucleus and stretched to the cavum vergae. PMID:16127534

Celik, Hakam H; Aldur, Mustafa M; Tatar, Ilkan; Ozkul, Emine; Tascioglu, Ayse B

2005-08-01

254

Alcohol Problems in lAter life  

E-print Network

Alcohol Problems in lAter life A Pacific Northwest Extension Publication Oregon State University When alcohol use becomes a problem ................. 4 How an alcohol problem develops ....................... 6 Recognizing an alcohol problem .......................... 8 Guidelines for family and friends

Tullos, Desiree

255

Cooling Therapy Helps Newborns Years Later  

MedlinePLUS

... Services Latest Issue This Issue Features Digging a Vegetarian Diet Massage Therapy Health Capsules Cooling Therapy Helps Newborns Years Later High Blood Pressure in Children Featured Website: Impact of NIH Research Past Issues ...

256

The lateral fixation screw in implant dentistry.  

PubMed

This clinical report presents a means of retaining implant supported superstructures using lateral fixation screws (Novadent). 244 lateral fixation screws have been used for the retention of a variety of restorations including single teeth, short span and full arch bridgework as well as overdenture bars. Over a period of observation of 4 years, the authors have found the restorations to have effective retention, ease of retrievability, good aesthetics and occlusal contours. PMID:11307389

Sethi, A; Sochor, P

2000-03-01

257

A Laterally Averaged Nonhydrostatic Ocean Model  

Microsoft Academic Search

Laterally-averaged dynamical equations are often used in numerical models of narrow coastal regions such as fjords and estuaries. Such models are preferable to 2D formulations, because they can handle variable-width effects such as flow acceleration at coastal constrictions. They also have a considerable speed advantage over 3D models. However, most laterally-averaged models share a significant weakness -- they rely on

Daniel Bourgault; Dan E. Kelley

2004-01-01

258

Brain and behavioral lateralization in invertebrates.  

PubMed

Traditionally, only humans were thought to exhibit brain and behavioral asymmetries, but several studies have revealed that most vertebrates are also lateralized. Recently, evidence of left-right asymmetries in invertebrates has begun to emerge, suggesting that lateralization of the nervous system may be a feature of simpler brains as well as more complex ones. Here I present some examples in invertebrates of sensory and motor asymmetries, as well as asymmetries in the nervous system. I illustrate two cases where an asymmetric brain is crucial for the development of some cognitive abilities. The first case is the nematode Caenorhabditis elegans, which has asymmetric odor sensory neurons and taste perception neurons. In this worm left/right asymmetries are responsible for the sensing of a substantial number of salt ions, and lateralized responses to salt allow the worm to discriminate between distinct salt ions. The second case is the fruit fly Drosophila melanogaster, where the presence of asymmetry in a particular structure of the brain is important in the formation or retrieval of long-term memory. Moreover, I distinguish two distinct patterns of lateralization that occur in both vertebrates and invertebrates: individual-level and population-level lateralization. Theoretical models on the evolution of lateralization suggest that the alignment of lateralization at the population level may have evolved as an evolutionary stable strategy in which individually asymmetrical organisms must coordinate their behavior with that of other asymmetrical organisms. This implies that lateralization at the population-level is more likely to have evolved in social rather than in solitary species. I evaluate this new hypothesis with a specific focus on insects showing different level of sociality. In particular, I present a series of studies on antennal asymmetries in honeybees and other related species of bees, showing how insects may be extremely useful to test the evolutionary hypothesis. PMID:24376433

Frasnelli, Elisa

2013-01-01

259

Brain and behavioral lateralization in invertebrates  

PubMed Central

Traditionally, only humans were thought to exhibit brain and behavioral asymmetries, but several studies have revealed that most vertebrates are also lateralized. Recently, evidence of left–right asymmetries in invertebrates has begun to emerge, suggesting that lateralization of the nervous system may be a feature of simpler brains as well as more complex ones. Here I present some examples in invertebrates of sensory and motor asymmetries, as well as asymmetries in the nervous system. I illustrate two cases where an asymmetric brain is crucial for the development of some cognitive abilities. The first case is the nematode Caenorhabditis elegans, which has asymmetric odor sensory neurons and taste perception neurons. In this worm left/right asymmetries are responsible for the sensing of a substantial number of salt ions, and lateralized responses to salt allow the worm to discriminate between distinct salt ions. The second case is the fruit fly Drosophila melanogaster, where the presence of asymmetry in a particular structure of the brain is important in the formation or retrieval of long-term memory. Moreover, I distinguish two distinct patterns of lateralization that occur in both vertebrates and invertebrates: individual-level and population-level lateralization. Theoretical models on the evolution of lateralization suggest that the alignment of lateralization at the population level may have evolved as an evolutionary stable strategy in which individually asymmetrical organisms must coordinate their behavior with that of other asymmetrical organisms. This implies that lateralization at the population-level is more likely to have evolved in social rather than in solitary species. I evaluate this new hypothesis with a specific focus on insects showing different level of sociality. In particular, I present a series of studies on antennal asymmetries in honeybees and other related species of bees, showing how insects may be extremely useful to test the evolutionary hypothesis. PMID:24376433

Frasnelli, Elisa

2013-01-01

260

Lateral tethering intraspinal lipoma with scoliosis  

Microsoft Academic Search

The authors present an unusual case of an intradural lipoma at the thoracolumbar level causing lateral tethering of the spine,\\u000a with complicated scoliosis. A 6-year-old girl was admitted with progressive change in posture detected by her parents. Thoracolumbar\\u000a scoliosis was detected by physical examination and X-ray studies. Spinal magnetic resonance imaging revealed an intradural\\u000a lipoma and right lateral tethering of

Bashar Abuzayed; Reza Dashti; Fatma Ozlen; Pamir Erdincler

2011-01-01

261

Lateralization of cognitive processes in the brain.  

PubMed

The lateralization of cognitive processes in the brain is discussed. The traditional view of a language-visuo/spatial dichotomy of function between the hemispheres has been replaced by more subtle distinctions. The use of magnetic resonance imaging (MRI) to study brain morphology has resulted in a renewed focus on the relationship between structural and functional asymmetry. Focus has been on the role played by the planum temporale area in the posterior part of the superior temporal gyrus for language asymmetry, and the possible significance of the larger left planum. The dichotic listening technique is used to illustrate the difference between bottom-up, or stimulus-driven laterality versus top-down, or instruction-driven laterality. It is suggested that the hemispheric dominance observed at any time is the sum result of the dynamic interaction between bottom-up and top-down processing tendencies. Stimulus-driven laterality dominance is always monitored and modulated through top-down cognitive processes, like shifting of attention and changes in arousal. A model of top-down modulation of bottom-up laterality is presented with special reference to the understanding of psychiatric disorders. PMID:11194413

Hugdahl, K

2000-12-01

262

Lateral restraint assembly for reactor core  

DOEpatents

A restraint assembly for use in restraining lateral movement of a reactor core relative to a reactor vessel wherein a plurality of restraint assemblies are interposed between the reactor core and the reactor vessel in circumferentially spaced relation about the core. Each lateral restraint assembly includes a face plate urged against the outer periphery of the core by a plurality of compression springs which enable radial preloading of outer reflector blocks about the core and resist low-level lateral motion of the core. A fixed radial key member cooperates with each face plate in a manner enabling vertical movement of the face plate relative to the key member but restraining movement of the face plate transverse to the key member in a plane transverse to the center axis of the core. In this manner, the key members which have their axes transverse to or subtending acute angles with the direction of a high energy force tending to move the core laterally relative to the reactor vessel restrain such lateral movement.

Gorholt, Wilhelm (San Diego, CA); Luci, Raymond K. (Del Mar, CA)

1986-01-01

263

Lateral flow immunoassay using magnetoresistive sensors  

NASA Astrophysics Data System (ADS)

Magnetic particles have been adapted for use as labels in biochemical lateral flow strip tests. Standard gold particle lateral flow assays are generally qualitative; however, with magnetic particles, quantitative results can be obtained by using electronic detection systems with giant magnetoresistive (GMR) sensors. As described here, these small integrated sensor chips can detect the presence of magnetic labels in capture spots whose volume is approximately 150 ?m×150 ?m×150 ?m. The range of linear detection is better than two orders of magnitude; the total range is up to four orders of magnitude. The system was demonstrated with both indirect and sandwich enzyme-linked immunosorbent assays (ELISAs) for protein detection of rabbit IgG and interferon-?, respectively, achieving detection of 12 pg/ml protein. Ultimately, the goal is for the detector to be fully integrated into the lateral flow strip backing to form a single consumable item that is interrogated by a handheld electronic reader.

Taton, Kristin; Johnson, Diane; Guire, Patrick; Lange, Erik; Tondra, Mark

2009-05-01

264

The Lateral Instability of Deep Rectangular Beams  

NASA Technical Reports Server (NTRS)

Experimental and analytical studies were made of solid and hollow deep rectangular beams to study their lateral instability under various conditions of loading and restraint. The tests were made on bars and tubes of 17ST aluminum alloy. Failure by lateral buckling occurred only in tests on the solid beams. It was found that, within the elastic range, the test results were in agreement with the classical theory for the lateral buckling of deep beams as given by Prandtl, Mitchell, and Timoshenko. The tests were extended to the inelastic range, where it was found that the substitution for Young's modulus of an average modulus of elasticity derived from the stress-strain curve made it possible to predict instability at high stresses.

Dumont, C; Hill, H N

1937-01-01

265

Mandibular Condyle Reconstruction with Free Costochondral Grafting  

Microsoft Academic Search

Reconstruction of the temporomandibular articulation is one of the most demanding challenges in maxillofacial surgery. The\\u000a goals include not only rehabilitation of the complex mechanism of the normal joint, but restoration of facial symmetry, occlusion,\\u000a and mastication. As advanced temporomandibular joint (TMJ) disease can lead to disturbances in these features and functions,\\u000a this often constitutes major indications for arthroplastic procedures.

Christian Lindqvist

266

Salvage Surgery for Lateral Tennis Elbow  

Microsoft Academic Search

We undertook a retrospective analysis of 34 patients (35 elbows) who had prior failed surgical intervention for lateral tennis elbow. Revision surgeries were per formed between 1979 and 1994. Each patient's non operative and operative history was recorded before our salvage revision surgery. At revision surgery, find ings included residual tendinosis of the extensor carpi radialis brevis tendon in 34

Scott W. Organ; Robert P. Nirschl; Barry S. Kraushaar; Eric J. Guidi

1997-01-01

267

Balance problems after unilateral lateral ankle sprains  

Microsoft Academic Search

Ankle ligament injury is the most common injury in athletic activities. This study examined balance problems in ath- letes with acute lateral ankle sprains. Thirty male athletes aged 20 to 35 years with right dominant side and traumatic ankle sprain were recruited through simple nonprobability sampling. We measured the sway index and limits of stability with the Bio- dex Balance

Mohammad Akbari; Hossein Karimi; Hossein Farahini; Soghrat Faghihzadeh

2006-01-01

268

Phylogenetic identification of lateral genetic transfer events  

Microsoft Academic Search

BACKGROUND: Lateral genetic transfer can lead to disagreements among phylogenetic trees comprising sequences from the same set of taxa. Where topological discordance is thought to have arisen through genetic transfer events, tree comparisons can be used to identify the lineages that may have shared genetic information. An 'edit path' of one or more transfer events can be represented with a

Robert G Beiko; Nicholas Hamilton

2006-01-01

269

Breaking the news in amyotrophic lateral sclerosis  

Microsoft Academic Search

Telling the diagnosis to patients with amyotrophic lateral sclerosis (ALS) is a daunting task for any neurologist. Obviously, breaking the news in ALS is not a standardizable procedure. However, proven techniques exist to reduce the trauma to the patient and ease the burden on the doctor, thus reducing the risk of burnout and the tendency to `pull away' from the

Gian Domenico Borasio; Richard Sloan; Dieter E Pongratz

1998-01-01

270

Is migraine a lateralization defect? Jani Kaaroa  

E-print Network

Is migraine a lateralization defect? Jani Kaaroa , Timo Partonenb , Paulami Naikc and Nouchine.1097/WNR.0b013e32830c4698 Migraine often co-occurs with patent foramen ovale (PFO), and some people have suggested surgical closure as an e/cient treat- mentfor migraine.Prospective studies, however, do

Hadjikhani, Nouchine

271

The Columbine Tragedy Ten Years Later  

ERIC Educational Resources Information Center

Some tragedies are so emblazoned in people's minds that years later they can recall where they were when they first heard the news. The assassinations of John F. Kennedy and Martin Luther King Jr., the Challenger explosion, and the Sept. 11 terrorist attacks are among these events. So also is the Columbine High School tragedy of April 20, 1999.…

Hammond, Jane

2009-01-01

272

Profiling 1366 Technologies: One Year Later  

ScienceCinema

Last January, we took a look at how ARPA-E performer, 1366 Technologies is working to dramatically reduce the cost of solar energy. A year later, we revisited their headquarters in Lexington, MA to see the progress they've made.

Van Mierlo, Frank; Sachs, Ely;

2013-05-29

273

PROCEEDINGS Open Access Lateral gene transfer, rearrangement,  

E-print Network

Transfers. We examine two datasets of gene trees from a single set of cyanobacteria species. The first setPROCEEDINGS Open Access Lateral gene transfer, rearrangement, reconciliation Murray Patterson1 Abstract Background: Models of ancestral gene order reconstruction have progressively integrated different

Paris-Sud XI, Université de

274

Towards gene therapy in amyotrophic lateral sclerosis  

Microsoft Academic Search

Amyotrophic lateral sclerosis (ALS) is a paralytic neurodegenerative disorder, characterised by a specific loss of motoneurons. Although the exact pathogenesis is largely enigmatic, it is known that glutamate excitotoxicity plays an important role in motoneuron cell death. Glutamate is one of the major neurotransmitters in the central nervous system. Relative high levels of glutamate can lead to motoneuron death by

Liselijn Agatha Barendina Wisman

2004-01-01

275

Active Children: Healthy Now And Later  

ERIC Educational Resources Information Center

Current research is revealing that physical activity can protect against a range of lifestyle diseases and illnesses. Consequently, early childhood practitioners and parents need to adopt guidelines and practices which encourage children of all ages to be physically active. In "Active children: Healthy Now and Later," authors Linley Campbell and…

Campbell, Linley; Musumeci, Josephine

2005-01-01

276

Stem cell treatment in Amyotrophic Lateral Sclerosis  

Microsoft Academic Search

Amyotrophic Lateral Sclerosis is a progressive fatal neurodegenerative disease that targets motor neurons. Its origin is unknown but a main role of reactive astrogliosis and microglia activation in the pathogenesis has been recently demonstrated. Surrounding neurons with healthy adjoining cells completely stops motor neuron death in some cases. Hence stem cell transplantation might represent a promising therapeutic strategy. In this

Letizia Mazzini; Katia Mareschi; Ivana Ferrero; Elena Vassallo; Giuseppe Oliveri; Nicola Nasuelli; Gaia Donata Oggioni; Lucia Testa; Franca Fagioli

2008-01-01

277

Stem cell treatment in Amyotrophic Lateral Sclerosis  

Microsoft Academic Search

Amyotrophic Lateral Sclerosis is a progressive fatal neurodegenerative disease that targets motor neurons. Its origin is unknown but a main role of reactive astrogliosis and microglia activation in the pathogenesis has been recently demonstrated. Surrounding neurons with healthy adjoining cells completely stops motor neuron death in some cases. Hence stem cell transplantation might represent a promising therapeutic strategy. In this

Letizia Mazzini; Katia Mareschi; Ivana Ferrero; Elena Vassallo; Giuseppe Oliveri; Nicola Nasuelli; Gaia Donata Oggioni; Lucia Testa; Franca Fagioli

2007-01-01

278

Lateralized Temporal Order Judgement in Dyslexia  

ERIC Educational Resources Information Center

Temporal and spatial attentional deficits in dyslexia were investigated using a lateralized visual temporal order judgment (TOJ) paradigm that allowed both sensitivity to temporal order and spatial attentional bias to be measured. Findings indicate that adult participants with a positive screen for dyslexia were significantly less sensitive to the…

Liddle, Elizabeth B.; Jackson, Georgina M.; Rorden, Chris; Jackson, Stephen R.

2009-01-01

279

Simulation of lateral flow with SWAT  

Technology Transfer Automated Retrieval System (TEKTRAN)

Calibration of the SWAT model for the Goodwater Creek Experimental Watershed (GCEW) showed that percolation through the restrictive claypan layer, lateral flow above that layer, and redistribution of excess moisture up to the ground surface were not correctly simulated. In addition, surface runoff a...

280

Laterality, Implicit Memory, and Attention Disorder.  

ERIC Educational Resources Information Center

Presents study showing children with behaviors characteristic of attention disorder/hyperactivity deficit and high intelligence have more mixed laterality and allergies. Finds these children gather and use more diverse nonverbal and poorly focused information. Concludes such children use uncommon information when exhibiting novelty in nonverbal…

Shaw, Geraldine A.; Brown, Geoffrey

1991-01-01

281

Molecular basis of amyotrophic lateral sclerosis  

Microsoft Academic Search

Amyotrophic lateral sclerosis (ALS) is a fatal disorder of motor neuron degeneration with unclear etiology and no effective treatment to date. ALS is, however, increasingly recognized as a multisystem disorder associated with impaired cognition. The overlap between ALS and dementia at clinical, genetic and neuropathologic levels indicates a spectrum of clinical phenotypes that may include features of frontotemporal lobar degeneration

Rajka M. Liscic; Davorka Breljak

2011-01-01

282

Profiling 1366 Technologies: One Year Later  

SciTech Connect

Last January, we took a look at how ARPA-E performer, 1366 Technologies is working to dramatically reduce the cost of solar energy. A year later, we revisited their headquarters in Lexington, MA to see the progress they've made.

Van Mierlo, Frank; Sachs, Ely

2011-01-01

283

Control augmentation for lateral control wheel steering  

NASA Technical Reports Server (NTRS)

Flight control system design for lateral control wheel steering is discussed. Two alternate designs are presented. The first design is a roll-rate command, bank-angle hold system with a wings-level track-hold submode. The second is a curved-track-hold system. Design details and real-time flight simulator results are included.

Foulkes, R. H., Jr.

1981-01-01

284

Preparing Future Faculty: Ten Years Later  

ERIC Educational Resources Information Center

When Sean Murphy designed the Graduate Student Internship Program at the College of Lake County (CLC), his 2001 TETYC article about the then two-year-old program detailed his programmatic response to the job market. Ten years later, the CLC-DePaul University partnership remains the strongest of the original dozen cross-sector relationships CLC…

Murphy, Sean P.; Aiossa, Elizabeth; Winter, Mary Mugica

2010-01-01

285

Depression in Later Life: Recognition and Treatment.  

ERIC Educational Resources Information Center

This guide is designed to help readers understand depression and factors related to its onset in later life; recognize signs of depression and potential suicide; and know actions they can take if they suspect an older family member or friend may be depressed or contemplating suicide. Following a brief introduction, a chapter on depression…

Schmall, Vicki L.; And Others

286

Lateral capacity of helical piles in clays  

SciTech Connect

Helical piles, also known as screw anchors, consist of one or more helical-shaped circular plates welded to a central steel shaft at a specified spacing. Currently, helical piles are being used as tower foundations on land and in offshore areas to secure moorings, cables, and sea-bed pipelines to the sea bed. In this paper, the behavior of helical piles under lateral loads in clayey soils is examined through an experimental investigation on model piles. Tests were conducted on rigid helical piles with different numbers of plates. Model anchors were made of 13.8 mm diameter mild steel shafts to which mild steel plates of 33 mm diameter were welded. For comparison, a single straight shaft with a diameter of 13.8 mm was also tested. Test results revealed that the lateral capacity of helical piles is greater than that of straight shaft piles. A simple theoretical model is suggested to estimate the lateral capacity of rigid helical piles. The theoretical model suggested incorporates lateral resistance of the soil on the shaft, bearing resistance on the bottom of the helical plate, uplift resistance on the top of the helical plate, and frictional resistance on the surface of the helical plate. The validity of this model is examined.

Prasad, Y.V.S.N. [Memorial Univ. of Newfoundland, St. John`s, Newfoundland (Canada). Faculty of Engineering and Applied Science] [Memorial Univ. of Newfoundland, St. John`s, Newfoundland (Canada). Faculty of Engineering and Applied Science

1996-11-01

287

Measuring acetabular component position on lateral radiographs - ischio-lateral method.  

PubMed

The standard method for the evaluation of arthritis and postoperative assessment of arthroplasty treatment is observation and measurement from plain films, using the flm edge for orientation. A more recent employment of an anatomical landmark, the ischial tuberosity, has come into use as orientation for evaluation and is called the ischio-lateral method. In this study, the use of this method was evaluated as a first report to the literature on acetabular component measurement using a skeletal reference with lateral radiographs. Postoperative radiographs of 52 hips, with at least three true lateral radiographs taken at different time periods, were analyzed. Component position was measured with the historical method (using the flm edge for orientation) and with the new method using the ischio-lateral method. The mean standard deviation (SD) for the historical approach was 3.7° and for the ischio-lateral method, 2.2° (p < 0.001). With the historical method, 19 (36.5%) hips had a SD greater than ± 4°, compared to six hips (11.5%) with the ischio-lateral method. By using a skeletal reference, the ischio-lateral method provides a more consistent measurement of acetabular component position. The high intra-class correlation coefficients for both intra- and inter-observer reliability indicate that the angle measured with this simple method, which employs no further technology, increased time, or cost, is consistent and reproducible for multiple observers. PMID:22035491

Pulos, Nicholas; Tiberi Iii, John V; Schmalzried, Thomas P

2011-01-01

288

A convex lateral tibial plateau for knee replacement  

Microsoft Academic Search

Unicompartmental knee replacements have not performed as well in the lateral compartment as in the medial. This may be because the tibial components have flat or slightly concave surfaces which match the medial plateau but not the convex lateral plateau. The aim of this study was to find the optimal radius for a convex lateral tibial component.Twelve normal lateral tibial

J. V. Baré; H. S. Gill; D. J. Beard; D. W. Murray

2006-01-01

289

A rare nonincisional lateral abdominal wall hernia.  

PubMed

A 68-year-old woman presented a rare lateral abdominal wall hernia. Three month before admission to Chungbuk National University Hospital, she found a large protruding mass measuring 8 cm in diameter in the midaxillary line just below the costal margin upon heavy coughing. She had no history of abdominal trauma, infection, or operation previously. The mass was easily reduced manually or by position change to left lateral decubitus. CT scan showed a defect of the right transversus abdominis muscle and internal oblique muscle at the right flank with omental herniation. Its location is different from that of spigelian hernia or lumbar hernia. The peritoneal lining of the hernia sac was smooth and there was no evidence of inflammation or adhesion. The hernia was successfully repaired laparoscopically using Parietex composite mesh with an intraperitoneal onlay mesh technique. The patient was discharged uneventfully and did not show any evidence of recurrence at follow-up visits. PMID:25692123

Kim, Dong-Ju; Park, Jin-Woo

2015-02-01

290

A new integrative model of lateral epicondylalgia.  

PubMed

Tennis elbow or lateral epicondylalgia is a diagnosis familiar to many within the general community and presents with an uncomplicated clinical picture in most cases. However, the underlying pathophysiology presents a more complex state and its management has not been conclusively determined. Research on this topic extends across anatomical, biomechanical and clinical literature; however, integration of findings is lacking. We propose that the current understanding of the underlying pathophysiology of lateral epicondylalgia can be conceptualised as encompassing three interrelated components: (i) the local tendon pathology, (ii) changes in the pain system, and (iii) motor system impairments. This paper presents a model that integrates these components on the basis of a literature review with the express aim of assisting in the targeting of specific treatments or combinations thereof to individual patients. PMID:19050004

Coombes, B K; Bisset, L; Vicenzino, B

2009-04-01

291

A rare nonincisional lateral abdominal wall hernia  

PubMed Central

A 68-year-old woman presented a rare lateral abdominal wall hernia. Three month before admission to Chungbuk National University Hospital, she found a large protruding mass measuring 8 cm in diameter in the midaxillary line just below the costal margin upon heavy coughing. She had no history of abdominal trauma, infection, or operation previously. The mass was easily reduced manually or by position change to left lateral decubitus. CT scan showed a defect of the right transversus abdominis muscle and internal oblique muscle at the right flank with omental herniation. Its location is different from that of spigelian hernia or lumbar hernia. The peritoneal lining of the hernia sac was smooth and there was no evidence of inflammation or adhesion. The hernia was successfully repaired laparoscopically using Parietex composite mesh with an intraperitoneal onlay mesh technique. The patient was discharged uneventfully and did not show any evidence of recurrence at follow-up visits. PMID:25692123

Kim, Dong-Ju

2015-01-01

292

Traumatic lumbosacral lateral dislocation without fracture  

Microsoft Academic Search

Study design  A unique case of lumbosacral lateral dislocation without fracture is reported.\\u000a \\u000a \\u000a \\u000a Objective  To report on the diagnosis and treatment of a traumatic L5-S1 lateral dislocation in a polytrauma 34-year-old male with L5\\u000a nerve root paralysis.\\u000a \\u000a \\u000a \\u000a Method  Interbody fusion following decompression, posterior reduction and interbody grafting combined with posterior plating was performed.\\u000a \\u000a \\u000a \\u000a Results  At an early stage the patient was able to return

Federico De Iure; Stefania Paderni; Alessandro Gasbarrini; Stefano Bandiera; Stefano Boriani

2008-01-01

293

Planar microlens relay optics utilizing lateral focusing.  

PubMed

We have proposed a novel concept of planar microlens relay optics with the goal of realizing alignment-free and multifunctional integrated optical subsystems. Since the planar microlens is one of its key elements, its lateral focusing characteristics were examined. The measured focusing spot size was 3 microm x 7 microm, which is comparable with the core of single-mode optical fibers. By measuring the refractive-index distribution, we found that the planar microlens produced by the electromigration method has a desirable index distribution that resembles that of a Luneburg lens. Thus we conclude that planar microlens relay optics may be facilitated when the lateral focusing property of planar microlenses is used. PMID:20733703

Intani, D; Baba, T; Iga, K

1992-09-01

294

Thrust vectoring for lateral-directional stability  

NASA Technical Reports Server (NTRS)

The advantages and disadvantages of using thrust vectoring for lateral-directional control and the effects of reducing the tail size of a single-engine aircraft were investigated. The aerodynamic characteristics of the F-16 aircraft were generated by using the Aerodynamic Preliminary Analysis System II panel code. The resulting lateral-directional linear perturbation analysis of a modified F-16 aircraft with various tail sizes and yaw vectoring was performed at several speeds and altitudes to determine the stability and control trends for the aircraft compared to these trends for a baseline aircraft. A study of the paddle-type turning vane thrust vectoring control system as used on the National Aeronautics and Space Administration F/A-18 High Alpha Research Vehicle is also presented.

Peron, Lee R.; Carpenter, Thomas

1992-01-01

295

Epidural Abscess Masquerading as Lateral Sinus Thrombosis  

PubMed Central

Controversy regarding the use of anticoagulants, the evacuation of the sinus, or the use of medical treatment alone surrounds the treatment of lateral sinus thrombosis. Treatment of an epidural abscess associated with coalescent mastoiditis is much less controversial-drainage is usually recommended. The differing treatments of these complications mandate accurate diagnosis. The advent of more sophisticated radiological studies has facilitated diagnosis of these complications; however, tests are not infallible. We present three cases in which preoperative imaging demonstrates an epidural abscess mimicking lateral sinus thrombosis by compression of the vessel. A false-positive computed tomography (CT) or magnetic resonance imaging (MRI) study may lead to the wrong diagnosis and, consequently, improper treatment. In light of this possibility, we recommend surgical exploration in all such cases. ImagesFigure 1Figure 2Figure 3Figure 4 PMID:17171148

Brodner, David C.; Cutler, Jeff; Gianoli, Gerard J.; Amedee, Ronald G.

2000-01-01

296

Later Tertiary Leporidae of North America  

E-print Network

of enamel and dentine. Other terms used for more primitive leporids and for unworn teeth usually follow Woo]) (1940). Skele- tal terms follow BENSLEY (1945) in most cases. The term postalveolar foramen has been used to designate a fora- men for the passage...; lateral portion of nasal extends farther posteriorly than remainder; supraorbital process of frontal present; in palatine process of maxilla, foramen premolare (BoHLIN, 1942a, p. 59-60) absent. The combination of characters listed above differen- tiates...

Dawson, M. R.

1958-05-01

297

Quantifiable Lateral Flow Assay Test Strips  

NASA Technical Reports Server (NTRS)

As easy to read as a home pregnancy test, three Quantifiable Lateral Flow Assay (QLFA) strips used to test water for E. coli show different results. The brightly glowing control line on the far right of each strip indicates that all three tests ran successfully. But the glowing test line on the middle left and bottom strips reveal their samples were contaminated with E. coli bacteria at two different concentrations. The color intensity correlates with concentration of contamination.

2003-01-01

298

DISCUSSION 5: Transitions in the Later Palaeolithic  

Microsoft Academic Search

\\u000a This paper discusses a number of concepts common to “transitions” in the Later Palaeolithic, whether change should be multifaceted\\u000a in nature involving more than one cultural or technological attribute to be accepted as a defining point in time; the extent\\u000a to which rate of change is important, be it gradual, accelerated, punctuated or uniform, and whether duration of change is

Rupert A. Housley

299

Neck-proprioceptive influence on auditory lateralization  

Microsoft Academic Search

The effect of transcutaneous vibration of the posterior neck muscles on the lateralization of dichotic sound was investigated\\u000a in human subjects. Two-alternative forced-choice (left\\/right) judgements were made on acoustic stimuli presented with different\\u000a interaural level differences via headphones during neck-muscle vibration. A shift of the subjective auditory median plane\\u000a toward the side contralateral of vibration was found, indicating that the

Jörg Lewald; Hans-Otto Karnath; Walter H. Ehrenstein

1999-01-01

300

Lateral stability of the proximal interphalangeal joint.  

PubMed

Current diagnostic criteria and therapeutic guidelines for injuries to the collateral ligaments of the proximal interphalangeal (PIP) joint are imprecise and vague. Laxity determinations, failure analysis, radiographic stress testing, and microscopic dissections were performed on 112 PIP joints. The lateral collateral ligament (LCL) is the primary restraint to varus and valgus angulation of the PIP joint. Its palmar fibers are tight in joint extension and provide the first line of resistance to lateral angulation. Failure of the LCL almost always occurs proximally in a sequential fashion that begins with the palmar fibers and progresses to the more dorsal bundles. Proximal LCL disruption is followed by separation of the accessory collateral-LCL junction and finally by failure of the distal palmar plate. Midsubstance tears of the LCL are rare. If the lateral stress test shows more than 20 degrees of varus or valgus angulation, the LCL can be presumed to be completely disrupted. Angulation of less than 20 degrees is associated with a 53% chance of partial LCL failure and a 47% chance of complete disruption, but the proper position of the LCL will be maintained by the overlying connective tissues. A clinical investigation will be necessary to define the criteria for surgical intervention. PMID:3760491

Kiefhaber, T R; Stern, P J; Grood, E S

1986-09-01

301

Lateral dominance in children with learning disabilities.  

PubMed

The purpose of the study was to investigate the occurrence of lateral dominance problems in a sample of children with learning disabilities. Ninety-one children (62 boys, 29 girls) who attended a school for children with learning disabilities were selected for the study. The Harris tests of lateral dominance were administered individually, and the children were rated as having right, left, or mixed dominance for hand, eye, and foot. When compared with normative data on dominance in children, the results showed that the occurrence of mixed hand dominance was no more frequent, the occurrence of mixed eye dominance was less frequent, and the occurrence of mixed foot dominance was more frequent in the children with learning disabilities. Results also showed that the occurrence of mixed and crossed eye-hand dominance was significantly different in children with learning disabilities when compared with children without learning disabilities. However, the occurrence of mixed eye-hand dominance was found to be significantly greater in children without learning disabilities than in learning disabled children. Age and sex were not found to affect the occurrence of lateral dominance problems in children with learning disabilities. PMID:6823468

Connolly, B H

1983-02-01

302

Lateral jet injection into typical combustor flowfields  

NASA Technical Reports Server (NTRS)

The experimental problem of lateral jet injection into typical flow fields in the absence of combustion was studied. All flow fields being investigated have no expansion of the crossflow (the test section to swirler diameter ratio D/d = 1), after its passage through an optional swirler (with swirl vane angle phi = 0 (swirler removed), 45, and 70 degree). The lateral jet(s) is(are) located one test-section diameter downstream of the test-section inlet (x/D = 1). The lateral jets have round-sectioned nozzles, each of which has an area of 1/100th of the cross sectional area of the crossflow (A sub j/A sub c = 1/100). Jet-to-crossflow velocity ratios of R = v sub j/u sub o = 2, 4, and 6 were investigated. Helium-bubble low visualization, five-hole pitot probe time-mean velocity measurements, and single-wire time-mean velocity and normal and shear stress turbulence data were obtained in the research program.

Lilley, D. G.

1986-01-01

303

Lateral balance control for robotic gait training.  

PubMed

For the rehabilitation of neurological patients robot-aided gait training is increasingly being used. Lack of balance training in these robotic gait trainers might contribute to the fact that they do not live up to the expectations. Therefore, in this study we developed and evaluated an algorithm to support lateral balance during walking, through controlling pelvis motions. This algorithm assists the pelvis, according to a natural pelvic sway pattern, rather than attracting it to the middle of the treadmill. The support algorithm was tested on six healthy young subjects who walked on a treadmill, while different support gains were introduced. Using a higher support gain resulted in a closer approximation of the pelvic sway towards the reference pattern. Step width and step width variability reduced when the external stabilization was provided, and the stability margin increased. This indicates that artificial stabilization reduces the need for active lateral balance control. The presented algorithm to support lateral balance provides a way to assist balance in a more physiological way, compared to attracting the subject to the centre of the treadmill. Here the user is attracted/assisted towards a more natural weight shift pattern. This also facilitates a more natural input of the load receptors, which are largely involved in the regulation of muscle activation patterns and the transitions between the different gait phases. PMID:24187182

Koopman, B; Meuleman, J H; van Asseldonk, E H F; van der Kooij, H

2013-06-01

304

Laterally-biased quantum dot infrared photodetector  

NASA Astrophysics Data System (ADS)

At the Air Force Research Laboratory, Space Vehicles Directorate, we are interested in improving the performance of or modifying the capabilities of infrared detectors in order to locate and identify dim and/or distant objects in space. One characteristic we are very interested in is multicolor detection. To this end, we have turned to a novel detector design that we have come to call a Lateral Quantum Dot Infrared Photodetector (LQDIP). In this design, InAs quantum dots are buried in a GaAs quantum well, which in turn is tunnel-coupled to another GaAs quantum well. Photoexcited electrons from the quantum dots tunnel over to the second well and are then swept out via a lateral (perpendicular to the growth direction) bias voltage. This architecture should exhibit the ability to tune to select infrared frequencies with reduced dark current and unity gain. The lateral photocurrent is directed by a vertical (parallel to the growth direction) gate voltage. We will discuss this detector architecture and the LQDIP operating principles and conditions, and we will present some preliminary results of current-voltage, photocurrent, differential conductance, and spectral measurements.

Cardimona, D. A.; Morath, C. P.; Guidry, D. H.; Cowan, V. M.

2013-07-01

305

Genetic factors and breast cancer laterality  

PubMed Central

Background Women are more likely to develop cancer in the left breast than the right. Such laterality may influence subsequent management, especially in elderly patients with heart disease who may require radiation therapy. The purpose of this study was to explore possible factors for such cancer laterality. Methods In this work, clinical data for consecutive patients with histologically confirmed breast cancer were reviewed, with emphasis on clinical presentation and family history. Results Between 2005 and 2012, 687 patients with breast cancer were seen. Two women with incomplete data and eleven men were excluded. In total, 343 (50.9%) patients presented with left breast cancer, 311 (46.1%) with right breast cancer, and 20 (3.0%) with simultaneous bilateral malignancy. There were no significant differences between the three groups, especially in regards to clinical presentation and tumor characteristics. A total of 622 (92.3%) patients had unilateral primary, 20 (3.0%) had simultaneous bilateral, and 32 (4.7%) had metachronous primary breast cancer with subsequent contralateral breast cancer after 7.5–236 months. The worst 10-year survival was for bilateral simultaneous (18%) compared with unilateral (28%) and metachronous primaries (90%). There were no differences in survival in relation to breast cancer laterality, handedness, and presence or absence of a family history of cancer. There were significant similarities between patients and first-degree relatives in regards to breast cancer laterality, namely same breast (30/66, 45.5%), opposite breast (9/66, 13.6%), and bilateral cancer (27/66, 40.9, P=0.01163). This was more evident among patients and their sisters (17/32, 53.1%) or mothers (11/27, 40.7%, P=0.0689). There were also close similarities in relation to age at initial diagnosis of cancer for patients and their first-degree relatives for age differences of ?5 years (48/166, 28.9%), 6–10 years (34/166, 20.5%), and >11 years (84/166, 50.6%, P=0.12065). Conclusion High similarities between patients and their first-degree relatives in regards to cancer laterality and possibly age at initial diagnosis of cancer may suggest an underlying inherited genetic predisposition. PMID:24790468

Amer, Magid H

2014-01-01

306

A lateral symmetrically bistable buckled beam  

NASA Astrophysics Data System (ADS)

We have micromachined a lateral symmetrically bistable buckled beam for snap-in holding structures by oxidizing released beams micromachined on thick silicon-on-insulator wafers. The wafers were prepared by bonding and chemical mechanical polishing, and the structures were fabricated by deep silicon reactive ion etching using the black silicon method, subsequently released and thermally oxidized. The bistability was monitored in situ in a scanning electron microscope using a micromanipulator. Guidelines for designing beams of an expected performance are given and arguments for considering beams that are not `fairly slender' have been found.

Vangbo, Mattias; Bäcklund, Ylva

1998-03-01

307

An anatomic and autologous lateral ankle stabilization.  

PubMed

A new technique for stabilization of the lateral ankle ligaments is presented. The procedure uses a split peroneus longus tendon to recreate the calcaneofibular and anterior talofibular ligaments. The new ligaments follow a precise anatomic course that replicates the pathway of the original ligaments. The procedure also capitalizes on interference screw technology so that accurate ligament tension can be obtained. This technique is most useful for severe ligamentous insufficiency involving both the calcaneofibular and anterior talofibular ligaments. Biomechanical rationale for the use of peroneus longus is also discussed. PMID:19857833

Schuberth, John M; Smith, Paul R; Jennings, Meagan M

2009-01-01

308

Towards reproducible, scalable lateral molecular electronic devices  

SciTech Connect

An approach to reproducibly fabricate molecular electronic devices is presented. Lateral nanometer-scale gaps with high yield are formed in Au/Pd nanowires by a combination of electromigration and Joule-heating-induced thermomechanical stress. The resulting nanogap devices are used to measure the electrical properties of small numbers of two different molecular species with different end-groups, namely 1,4-butane dithiol and 1,5-diamino-2-methylpentane. Fluctuations in the current reveal that in the case of the dithiol molecule devices, individual molecules conduct intermittently, with the fluctuations becoming more pronounced at larger biases.

Durkan, Colm, E-mail: cd229@eng.cam.ac.uk; Zhang, Qian [Nanoscience Centre, University of Cambridge, 9 JJ Thomson Avenue, Cambridge CB3 0FA (United Kingdom)

2014-08-25

309

Responsiveness-to-Intervention: A Decade Later  

PubMed Central

In this introduction to this special issue, “A Decade Later,” we provide an overview of the accomplishments as well as the persistent questions surrounding RTI. We organize this discussion within 3 categories: assessment, instruction, and policy. Within each of these sections, we also highlight how the articles in the present special issue expand upon the key issues. Developed initially for the early grades (kindergarten through third grade) and primarily in the area of reading, many-although not all-of these issues speak to the expansion of RTI to address a broader set of academic content areas and the full range of grade levels. PMID:22539056

Fuchs, Lynn S.; Vaughn, Sharon

2012-01-01

310

Towards reproducible, scalable lateral molecular electronic devices  

NASA Astrophysics Data System (ADS)

An approach to reproducibly fabricate molecular electronic devices is presented. Lateral nanometer-scale gaps with high yield are formed in Au/Pd nanowires by a combination of electromigration and Joule-heating-induced thermomechanical stress. The resulting nanogap devices are used to measure the electrical properties of small numbers of two different molecular species with different end-groups, namely 1,4-butane dithiol and 1,5-diamino-2-methylpentane. Fluctuations in the current reveal that in the case of the dithiol molecule devices, individual molecules conduct intermittently, with the fluctuations becoming more pronounced at larger biases.

Durkan, Colm; Zhang, Qian

2014-08-01

311

Quantifying Disease Progression in Amyotrophic Lateral Sclerosis  

PubMed Central

Amyotrophic lateral sclerosis (ALS) exhibits characteristic variability of onset and rate of disease progression, with inherent clinical heterogeneity making disease quantitation difficult. Recent advances in understanding pathogenic mechanisms linked to the development of ALS impose an increasing need to develop strategies to predict and more objectively measure disease progression. This review explores phenotypic and genetic determinants of disease progression in ALS, and examines established and evolving biomarkers that may contribute to robust measurement in longitudinal clinical studies. With targeted neuroprotective strategies on the horizon, developing efficiencies in clinical trial design may facilitate timely entry of novel treatments into the clinic. PMID:25223628

Simon, Neil G; Turner, Martin R; Vucic, Steve; Al-Chalabi, Ammar; Shefner, Jeremy; Lomen-Hoerth, Catherine; Kiernan, Matthew C

2014-01-01

312

Lateral tunneling through voltage-controlled barriers  

NASA Technical Reports Server (NTRS)

The paper reports on a detailed experimental investigation of lateral tunneling between electrodes of a two-dimensional electron gas separated by the voltage-controlled barrier of a nanometer Schottky gate. The experimental data are modeled using the WKB method to calculate the tunneling probability of electrons through a barrier whose shape is determined from a solution of the two-dimensional Poisson equation. This model is in excellent agreement with the experimental data over a two order of magnitude range of current.

Manion, S. J.; Bell, L. D.; Kaiser, W. J.; Maker, P. D.; Muller, R. E.

1991-01-01

313

AXR1 Acts after Lateral Bud Formation to Inhibit Lateral Bud Growth in Arabidopsis1  

PubMed Central

The AXR1 gene of Arabidopsis is required for many auxin responses. The highly branched shoot phenotype of mature axr1 mutant plants has been taken as genetic evidence for a role of auxin in the control of shoot branching. We compared the development of lateral shoots in wild-type Columbia and axr1-12 plants. In the wild type, the pattern of lateral shoot development depends on the developmental stage of the plant. During prolonged vegetative growth, axillary shoots arise and develop in a basal-apical sequence. After floral transition, axillary shoots arise rapidly along the primary shoot axis and grow out to form lateral inflorescences in an apical-basal sequence. For both patterns, the axr1 mutation does not affect the timing of axillary meristem formation; however, subsequent lateral shoot development proceeds more rapidly in axr1 plants. The outgrowth of lateral inflorescences from excised cauline nodes of wild-type plants is inhibited by apical auxin. axr1-12 nodes are resistant to this inhibition. These results provide evidence for common control of axillary growth in both patterns, and suggest a role for auxin during the late stages of axillary shoot development following the formation of the axillary bud and several axillary leaf primordia. PMID:10557232

Stirnberg, Petra; Chatfield, Steven P.; Leyser, H.M. Ottoline

1999-01-01

314

Medial patellar subluxation without previous lateral release: a case report.  

PubMed

Medial patellar subluxation (MPS) is normally described following a lateral release. We report on a 14-year-old girl with MPS without previous lateral release. Arthroscopic examination demonstrated MPS at 0 and 30° of flexion, and the patella was tight in flexion on the lateral side. A low lateral release with a tibial tubercle transfer was performed, followed by repair of the lateral release with an iliotibial band flap, and lateral patellofemoral ligament reconstruction. Excellent functional outcome was achieved. This type of patellar instability is often overlooked and a high index of suspicion is needed for appropriate diagnosis and treatment. PMID:24755851

Saper, Michael G; Shneider, David A

2014-07-01

315

Lateral Distribution Functions of Extensive Air Showers  

NASA Astrophysics Data System (ADS)

The energy is among the characteristics of Ultra High Energy Cosmic Rays (E>5 x 1019 eV) which could be estimated experimentally. The following paper attempts to estimate the energy of an UHECR proton by applying a Monte Carlo simulation code. A number of extensive air showers, vertical and inclined, is simulated to derive the Lateral Distribution Functions of the shower muons. The scenario of simulations is adopted to the Cerenkov surface detector of the P. AUGER Observatory. Due to the fact that the Lateral Distribution Functions show minimal fluctuations of the muon density at a distance larger than 800 m from the core of the showers, and due to the fact that at a distance of 900 m the distribution functions for inclined showers coincide (which means that it does not change with the zenith angle of the showers), we select the muon density at 900 m to derive the energy of the primary protons. (The project is co-funded by the European Social Fund and National Resources (EPEAEK II) PYTHAGORAS II.)

Geranios, A.; Fokitis, E.; Maltezos, S.; et al.

316

Lateral epicondylalgia: midlife crisis of a tendon.  

PubMed

The pathogenesis and management of lateral epicondylalgia, or tennis elbow, a common ailment affecting middle-aged subjects of both genders continue to provoke controversy. Currently it is thought to be due to local tendon pathology, pain system changes, and motor system impairment. Its diagnosis is usually clinical, based on a classical history, as well as symptoms and signs. In selected cases, additional imaging (X-rays, ultrasound, and magnetic resonance imaging) can help to confirm the diagnosis. Different treatment modalities have been described, including the use of orthotics, non-steroidal anti-inflammatory drugs, steroid injections, topical glyceryl trinitrate, exercise therapy, manual therapy, ultrasound therapy, laser therapy, extracorporeal shockwave therapy, acupuncture, taping, platelet-rich plasma injections, hyaluronan gel injections, botulinum toxin injections, and surgery. Nevertheless, evidence to select the best treatment is lacking and the choice of therapy depends on the experience of the management team, availability of the equipment and expertise, and patient response. This article provides a snapshot of current medical practice for lateral epicondylalgia management. PMID:24584568

Luk, James K H; Tsang, Raymond C C; Leung, H B

2014-04-01

317

Nappe emplacement under lateral pressure gradient  

NASA Astrophysics Data System (ADS)

New thin viscous approximation is under development specifically targeted to model spontaneous initiation and tens of kilometers horizontal displacement of tectonic nappes. Nappes are few kilometers thing and tens of kilometers long rock units trusted towards foreland often preserving internal lithological consistency and laying at near horizontal position at the end of the emplacement. Significant shear stresses and deviation of principal stresses from vertical is required to explain this very peculiar strain localization style from mechanical point of view. There is also a need for the explanation of their common appearances in most collisional settings. Both pure shear thin sheet and flexural models kinematically eliminate nappes formation. Spreading viscous sheet models, such as used to model glaciers, are also not applicable as the direction of motion is upward, against gravity. The reason for this discrepancy is the hydrostatic pressure approximation of the gravity-driven spreading models. Actually, the thin sheet approximation is not sensitive to the assumptions made on pressure profile. Lateral non-lithostatic pressure gradient-driven viscous sheet model is appropriate for modeling of nappes. In turn, significant non-lithostatic pressure must be supported by flexural rigidity of overlying and underlying units. Lateral gradients of this non-lithostatic pressure are responsible for the significant shear stress and, therefore, deviation of principal stress from vertical.

Podladchikov, Yury; Schmalholz, Stefan

2014-05-01

318

Dual-domain lateral shearing interferometer  

DOEpatents

The phase-shifting point diffraction interferometer (PS/PDI) was developed to address the problem of at-wavelength metrology of extreme ultraviolet (EUV) optical systems. Although extremely accurate, the fact that the PS/PDI is limited to use with coherent EUV sources, such as undulator radiation, is a drawback for its widespread use. An alternative to the PS/PDI, with relaxed coherence requirements, is lateral shearing interferometry (LSI). The use of a cross-grating, carrier-frequency configuration to characterize a large-field 4.times.-reduction EUV lithography optic is demonstrated. The results obtained are directly compared with PS/PDI measurements. A defocused implementation of the lateral shearing interferometer in which an image-plane filter allows both phase-shifting and Fourier wavefront recovery. The two wavefront recovery methods can be combined in a dual-domain technique providing suppression of noise added by self-interference of high-frequency components in the test-optic wavefront.

Naulleau, Patrick P.; Goldberg, Kenneth Alan

2004-03-16

319

Prototype cantilevers for quantitative lateral force microscopy  

SciTech Connect

Prototype cantilevers are presented that enable quantitative surface force measurements using contact-mode atomic force microscopy (AFM). The ''hammerhead'' cantilevers facilitate precise optical lever system calibrations for cantilever flexure and torsion, enabling quantifiable adhesion measurements and friction measurements by lateral force microscopy (LFM). Critically, a single hammerhead cantilever of known flexural stiffness and probe length dimension can be used to perform both a system calibration as well as surface force measurements in situ, which greatly increases force measurement precision and accuracy. During LFM calibration mode, a hammerhead cantilever allows an optical lever ''torque sensitivity'' to be generated for the quantification of LFM friction forces. Precise calibrations were performed on two different AFM instruments, in which torque sensitivity values were specified with sub-percent relative uncertainty. To examine the potential for accurate lateral force measurements using the prototype cantilevers, finite element analysis predicted measurement errors of a few percent or less, which could be reduced via refinement of calibration methodology or cantilever design. The cantilevers are compatible with commercial AFM instrumentation and can be used for other AFM techniques such as contact imaging and dynamic mode measurements.

Reitsma, Mark G.; Gates, Richard S.; Friedman, Lawrence H.; Cook, Robert F. [Nanomechanical Properties Group, National Institute of Standards and Technology, Gaithersburg, Maryland 20899 (United States)

2011-09-15

320

Revisiting cognitive rehearsal as an intervention against incivility and lateral violence in nursing: 10 years later.  

PubMed

Ten years ago, Griffin wrote an article on the use of cognitive rehearsal as a shield for lateral violence. Since then, cognitive rehearsal has been used successfully in several studies as an evidence-based strategy to address uncivil and bullying behaviors in nursing. In the original study, 26 newly licensed nurses learned about lateral violence and used cognitive rehearsal techniques as an intervention for nurse-to-nurse incivility. The newly licensed nurses described using the rehearsed strategies as difficult, yet successful in reducing or eliminating incivility and lateral violence. This article updates the literature on cognitive rehearsal and reviews the use of cognitive rehearsal as an evidence-based strategy to address incivility and bullvina behaviors in nursing. PMID:25406637

Griffin, Martha; Clark, Cynthia M

2014-12-01

321

Strath Terraces, Lateral Planation, and Sediment Supply  

NASA Astrophysics Data System (ADS)

Abandoned fluvially eroded bedrock surfaces (strath terraces) are used ubiquitously as indicators of past river elevation. However, little is known about how, why and over what time period they form. Consequently, dates of strath surfaces, or overlying gravels, can be difficult to interpret without a more mechanistic understanding of strath genesis. We mapped strath terraces in detail in the field along the South Fork Eel River and its tributaries in the California Coast Ranges to illuminate the process(es) of lateral bedrock planation. We document two straths along the South Fork Eel: a high strath terrace with a bedrock surface at 9-12 m above the modern low water line and a low strath terrace with a bedrock elevation 2-5 m above modern low water line. Straths are capped with up to 6 meters of gravel, and are locally as much as 3 times the width of the modern river channel. The South Fork Eel incises interbedded sandstone and mudstone of the Franciscan Complex. Straths are usually, but not always, formed in the weaker mudstone. This is consistent with observations in the active river channel indicating mudstone is readily planed down to the low water line by weathering processes and abrasion, whereas sandstone forms resistant ribs that locally constrict the flow. Our observations suggest at least two primary mechanisms drive the lateral planation essential to preserving straths. First, many strath terraces along the South Fork Eel are exposed at the toe of inactive debris fans that entered the channel from tributaries and graded to the higher strath elevation. In these settings, the river has almost always cut vertically through the strath between the outside edge of the fan and a bedrock wall. We interpret this as evidence that when the debris fan was active and the river occupied the high strath, the river was pinned by the debris fan against a bedrock valley wall. This, in turn, suggests lateral sediment input from fans may be important in driving lateral motion of the river. Second, where there is no significant lateral sediment input, straths appear to form at channel meanders. Observations in the active channel suggest that mudstone bedrock will erode much more readily than bars or fans, which are both comprised almost entirely of resistant sandstone boulders. We hypothesize that deposition of point bars, island bars, and debris fans therefore provides a mechanism to preferentially armor one bank of an active channel, leading to erosion of the other bank where mudstone is present. Importantly, along the South Fork Eel the majority of straths appear to form unidirectionally, that is via one continuous sweep of the channel across the strath. Recent dating of strath terraces along the South Fork Eel by others (and additional samples awaiting dating) will be used to evaluate this hypothesis. We assess recent proposals that strath terrace formation on the South Fork Eel is associated with a doubling of hillslope erosion by running HEC- RAS on a LiDAR DEM of the South Fork Eel to model bed sediment transport and bed evolution under different sediment supply scenarios. A primary goal is to explore how up to 6 m of aggradation could be associated with strath terrace formation.

Finnegan, N. J.; Dietrich, W. E.

2008-12-01

322

Macroscopic Lateral Heterogeneity Observed in a Laterally-Mobile Immiscible Mixed Polyelectrolyte/Neutral Polymer Brush  

PubMed Central

We studied mixed poly(ethylene oxide) (PEO) and poly(2-(dimethylamino)ethyl methacrylate) (PDMAEMA) brushes. The question we attempted to answer was: When the chain grafting points are laterally mobile, how will this lateral mobility influence the structure and phase behavior of the mixed brush? Three different model mixed PEO/PDMAEMA brush systems were prepared: (1) a laterally-mobile mixed brush by spreading onto the air-water interface a mixture of poly(ethylene oxide)-poly(n-butyl acrylate) (PEO-PnBA) and poly(2-(dimethylamino)ethyl methacrylate)-poly(n-butyl acrylate) (PDMAEMA-PnBA) diblock copolymers (the specific diblock copolymers used will be denoted as PEO113-PnBA100 and PDMAEMA118-PnBA100, where the subscripts refer to the number-average degrees of polymerization of the individual blocks), (2) a mobility-restricted (inseparable) version of the above mixed brush prepared using a PEO-PnBA-PDMAEMA triblock copolymer (denoted as PEO113-PnBA89-PDMAEMA120) having respective brush molecular weights matched to those of the diblock copolymers, and (3) a different laterally-mobile mixed PEO and PDMAEMA brush prepared from a PEO113-PnBA100 and PDMAEMA200-PnBA103 diblock copolymer combination, which represents a further more height-mismatched mixed brush situation than described in (1). These three mixed brush systems were investigated by surface pressure-area isotherm and X-ray (XR) reflectivity measurements. These experimental data were analyzed within the theoretical framework of a continuum self-consistent field (SCF) polymer brush model. The combined experimental and theoretical results suggest that the mobile mixed brush derived using the PEO113-PnBA100 and PDMAEMA118-PnBA100 combination (i.e., Mixed Brush System #1) undergoes a lateral macroscopic phase separation at high chain grafting densities, whereas the more height-mismatched system (System #3) is only microscopically phase separated under comparable brush density conditions even though the lateral mobility of the grafted chains is unrestricted. The macroscopic phase separation observed in the laterally-mobile mixed brush system is in contrast to the microphase separation behavior commonly observed in two-dimensional laterally-mobile charged small molecule mixtures. Further study is needed to determine the detailed morphologies of the macro and microphase-separated mixed PEO/PDMAEMA brushes. PMID:24695635

Lee, Hoyoung; Tsouris, Vasilios; Lim, Yunho; Mustafa, Rafid; Choi, Je; Choi, Yun Hwa; Park, Hae-Woong; Meron, Mati; Lin, Binhua; Won, You-Yeon

2015-01-01

323

Macroscopic lateral heterogeneity observed in a laterally mobile immiscible mixed polyelectrolyte-neutral polymer brush.  

PubMed

We studied mixed poly(ethylene oxide) (PEO) and poly(2-(dimethylamino)ethyl methacrylate) (PDMAEMA) brushes. The question we attempted to answer was: when the chain grafting points are laterally mobile, how will this lateral mobility influence the structure and phase behavior of the mixed brush? Three different model mixed PEO/PDMAEMA brush systems were prepared: (1) a laterally mobile mixed brush by spreading onto the air-water interface a mixture of poly(ethylene oxide)-poly(n-butyl acrylate) (PEO-PnBA) and poly(2-(dimethylamino)ethyl methacrylate)-poly(n-butyl acrylate) (PDMAEMA-PnBA) diblock copolymers (the specific diblock copolymers used will be denoted as PEO113-PnBA100 and PDMAEMA118-PnBA100, where the subscripts refer to the number-average degrees of polymerization of the individual blocks), (2) a mobility-restricted (inseparable) version of the above mixed brush prepared using a PEO-PnBA-PDMAEMA triblock copolymer (denoted as PEO113-PnBA89-PDMAEMA120) having respective brush molecular weights matched with those of the diblock copolymers, and (3) a different laterally mobile mixed PEO and PDMAEMA brush prepared from a PEO113-PnBA100 and PDMAEMA200-PnBA103 diblock copolymer combination, which represents a further more height-mismatched mixed brush situation than described in (1). These three mixed brush systems were investigated by surface pressure-area isotherm and X-ray (XR) reflectivity measurements. These experimental data were analyzed within the theoretical framework of a continuum self-consistent field (SCF) polymer brush model. The combined experimental and theoretical results suggest that the mobile mixed brush derived using the PEO113-PnBA100 and PDMAEMA118-PnBA100 combination (i.e., mixed brush System #1) undergoes a lateral macroscopic phase separation at high chain grafting densities, whereas the more height-mismatched system (System #3) is only microscopically phase separated under comparable brush density conditions even though the lateral mobility of the grafted chains is unrestricted. The macroscopic phase separation observed in the laterally mobile mixed brush system is in contrast with the microphase separation behavior commonly observed in two-dimensional laterally mobile charged small molecule mixtures. Further study is needed to determine the detailed morphologies of the macro- and microphase-separated mixed PEO/PDMAEMA brushes. PMID:24695635

Lee, Hoyoung; Tsouris, Vasilios; Lim, Yunho; Mustafa, Rafid; Choi, Je; Choi, Yun Hwa; Park, Hae-Woong; Meron, Mati; Lin, Binhua; Won, You-Yeon

2014-06-01

324

Magnetic resonance imaging in lateral sinus hypoplasia and thrombosis.  

PubMed

Lateral sinus thrombosis may be difficult to differentiate angiographically from lateral sinus hypoplasia, which mainly affects its proximal transverse portion. Using magnetic resonance imaging, we evaluated six patients who demonstrated poor filling or lack of filling of one or both lateral sinuses at angiography. In each patient, magnetic resonance imaging unambiguously demonstrated either lateral sinus thrombosis or lateral sinus hypoplasia. The latter was characterized by a frank asymmetry in size (surface of section) of the transverse portion of the lateral sinuses on parasagittal images without any abnormal signal in the course of the sinus. Lateral sinus thrombosis was indicated by increased intraluminal signal on all planes and with all pulse sequences. By virtue of its freedom from bone-related artifact, its multiplanar imaging capability, and its sensitivity to both blood flow and thrombus formation, magnetic resonance imaging is an excellent tool for the evaluation of lateral sinus thrombosis or hypoplasia. PMID:2396274

Mas, J L; Meder, J F; Meary, E; Bousser, M G

1990-09-01

325

Diagnosis and Treatment of Lateral Patellar Compression Syndrome  

PubMed Central

Chronic anterior knee pain with a stable patella is often associated with overload and increased pressure on the lateral facet due to pathologic lateral soft-tissue restraints. “Lateral pressure in flexion” is a term describing the pathologic process of increasing contact pressure over the lateral patellar facet as knee flexion progresses. This report describes a surgical technique developed in response to lateral pressure in flexion and the shortcomings of traditional arthroscopic lateral release procedures. The technique is performed open with the knee in flexion, and the lateral release is repaired with a rotation flap of iliotibial band to close the defect and prevent patellar subluxation. The technique effectively decreases lateral patellar pressure and centers the patella correctly in the trochlear groove with minimal risk of iatrogenic patellar instability. PMID:25473620

Saper, Michael G.; Shneider, David A.

2014-01-01

326

In situ hydrodynamic lateral force calibration of AFM colloidal probes.  

PubMed

Lateral force microscopy (LFM) is an application of atomic force microscopy (AFM) to sense lateral forces applied to the AFM probe tip. Recent advances in tissue engineering and functional biomaterials have shown a need for the surface characterization of their material and biochemical properties under the application of lateral forces. LFM equipped with colloidal probes of well-defined tip geometries has been a natural fit to address these needs but has remained limited to provide primarily qualitative results. For quantitative measurements, LFM requires the successful determination of the lateral force or torque conversion factor of the probe. Usually, force calibration results obtained in air are used for force measurements in liquids, but refractive index differences between air and liquids induce changes in the conversion factor. Furthermore, in the case of biochemically functionalized tips, damage can occur during calibration because tip-surface contact is inevitable in most calibration methods. Therefore, a nondestructive in situ lateral force calibration is desirable for LFM applications in liquids. Here we present an in situ hydrodynamic lateral force calibration method for AFM colloidal probes. In this method, the laterally scanned substrate surface generated a creeping Couette flow, which deformed the probe under torsion. The spherical geometry of the tip enabled the calculation of tip drag forces, and the lateral torque conversion factor was calibrated from the lateral voltage change and estimated torque. Comparisons with lateral force calibrations performed in air show that the hydrodynamic lateral force calibration method enables quantitative lateral force measurements in liquid using colloidal probes. PMID:21905684

Ryu, Sangjin; Franck, Christian

2011-11-01

327

ELECTRICAL RESPONSES FROM LATERAL-LINE NERVES OF FISHES. III  

PubMed Central

Evidence indicates that lateral-line fibers, other than those mediating the "spontaneous" activity of the lateral-line receptors, are brought into play in response to pressure stimuli in catfish and in trout. The distribution and mode of stimulation of mechanoreceptors along the lateral-lines of trout and catfish are discussed in relation to the natural activities of these forms. PMID:19872765

Hoagland, Hudson

1933-01-01

328

Predicting Later-Life Outcomes of Early-Life Exposures  

EPA Science Inventory

Background: In utero exposure of the fetus to a stressor can lead to disease in later life. Epigenetic mechanisms are likely mediators of later-life expression of early-life events.Objectives: We examined the current state of understanding of later-life diseases resulting from ea...

329

Superficial lateral line sense organs of the mudminnow ( Umbra limi )  

Microsoft Academic Search

Umbra limi has an elaborate developement of superficial neuromasts on the head and body. The individual lateral line organs of the head form rows. Intermittant clusters of organs occur on the body. The “lateral line“ consists of free standing organs, which are oriented alternating horizontally and vertically. A lateral line canal is wanting.

Erich Schwartz; Arthur D. Hasler

1966-01-01

330

Sex Differences in Cerebral Laterality of Language and Visuospatial Processing  

ERIC Educational Resources Information Center

Sex differences on language and visuospatial tasks are of great interest, with differences in hemispheric laterality hypothesized to exist between males and females. Some functional imaging studies examining sex differences have shown that males are more left lateralized on language tasks and females are more right lateralized on visuospatial…

Clements, A. M.; Rimrodt, S. L.; Abel, J. R.; Blankner, J. G.; Mostofsky, S. H.; Pekar, J. J.; Denckla, M. B.; Cutting, L. E.

2006-01-01

331

The management of the popliteus hiatus during lateral meniscal transplantation.  

PubMed

Popliteofascicular injury had been proposed as a possible cause of unstable lateral meniscus. Meniscal repair at popliteal hiatus area during lateral meniscal allograft transplantation (MAT) had not been described in literature previously. In this report, a case of unstable lateral meniscus after MAT has been described. Arthroscopic repair for the unstable meniscus at popliteal hiatus resolved the mechanical symptom. PMID:22578893

Yang, Jae-Hyuk; Jeong, Hyeon-Il; Kim, Taik-Sun; Park, Sung-Chul; Yoon, Jung-Ro

2012-12-01

332

The Relationship Between Lateral Dominance and Divergent Cognitive Thought.  

ERIC Educational Resources Information Center

This study was designed to explore the relationship of lateral dominance to divergent cognitive thought. According to the screening results of the Harris Tests of Lateral Dominance, 36 subjects ranging from 9-12 years were divided equally into three groups of left, right, and mixed lateral dominance. In order to measure divergent cognitive…

Williams, Barbara B.

333

Lateralized eye use in Octopus vulgaris shows antisymmetrical distribution  

Microsoft Academic Search

Behavioural lateralization has been demonstrated in many species of vertebrates, but there has been scarce evidence for it in invertebrates. We have previously documented lateral asymmetry of eye use in individual octopuses. In the present study we investigated lateralization at the population level. Octopus eyes are on the sides of the head, and these animals prefer monocular to binocular vision.

Ruth A. Byrne; Michael J. Kuba; Daniela V. Meisel

2004-01-01

334

Autoimmune disease preceding amyotrophic lateral sclerosis  

PubMed Central

Objective: To study whether the risk of amyotrophic lateral sclerosis (ALS) is increased in people with prior autoimmune disease. Methods: An all-England hospital record-linkage dataset spanning 1999–2011 was used. Cohorts were constructed of people with each of a range of autoimmune diseases; the incidence of ALS in each disease cohort was compared with the incidence of ALS in a cohort of individuals without prior admission for the autoimmune disease. Results: There were significantly more cases than expected of ALS associated with a prior diagnosis of asthma, celiac disease, younger-onset diabetes (younger than 30 years), multiple sclerosis, myasthenia gravis, myxedema, polymyositis, Sjögren syndrome, systemic lupus erythematosus, and ulcerative colitis. Conclusions: Autoimmune disease associations with ALS raise the possibility of shared genetic or environmental risk factors. PMID:23946298

Goldacre, Raph; Ramagopalan, Sreeram; Talbot, Kevin; Goldacre, Michael J.

2013-01-01

335

Large-scale lateral nanowire arrays nanogenerators  

DOEpatents

In a method of making a generating device, a plurality of spaced apart elongated seen members are deposited onto a surface of a flexible non-conductive substrate. An elongated conductive layer is applied to a top surface and a first side of each seed member, thereby leaving an exposed second side opposite the first side. A plurality of elongated piezoelectric nanostructures is grown laterally from the second side of each seed layer. A second conductive material is deposited onto the substrate adjacent each elongated first conductive layer so as to be soupled the distal end of each of the plurality of elongated piezoelectric nanostructures. The second conductive material is selected so as to form a Schottky barrier between the second conductive material and the distal end of each of the plurality of elongated piezoelectric nanostructures and so as to form an electrical contact with the first conductive layer.

Wang, Zhong L; Xu, Chen; Qin, Yong; Zhu, Guang; Yang, Rusen; Hu, Youfan; Zhang, Yan

2014-01-07

336

Amyotrophic lateral sclerosis: update and new developments  

PubMed Central

Amyotrophic lateral sclerosis (ALS) is the most common form of motor neuron disease. It is typically characterized by adult-onset degeneration of the upper and lower motor neurons, and is usually fatal within a few years of onset. A subset of ALS patients has an inherited form of the disease, and a few of the known mutant genes identified in familial cases have also been found in sporadic forms of ALS. Precisely how the diverse ALS-linked gene products dictate the course of the disease, resulting in compromised voluntary muscular ability, is not entirely known. This review addresses the major advances that are being made in our understanding of the molecular mechanisms giving rise to the disease, which may eventually translate into new treatment options. PMID:23019386

Pratt, Ashley J; Getzoff, Elizabeth D; Perry, J Jefferson P

2012-01-01

337

Inertia and scaling in deterministic lateral displacement  

PubMed Central

The ability to separate and analyze chemical species with high resolution, sensitivity, and throughput is central to the development of microfluidics systems. Deterministic lateral displacement (DLD) is a continuous separation method based on the transport of species through an array of obstacles. In the case of force-driven DLD (f-DLD), size-based separation can be modelled effectively using a simple particle-obstacle collision model. We use a macroscopic model to study f-DLD and demonstrate, via a simple scaling, that the method is indeed predominantly a size-based phenomenon at low Reynolds numbers. More importantly, we demonstrate that inertia effects provide the additional capability to separate same size particles but of different densities and could enhance separation at high throughput conditions. We also show that a direct conversion of macroscopic results to microfluidic settings is possible with a simple scaling based on the size of the obstacles that results in a universal curve. PMID:24396545

Bowman, Timothy J.; Drazer, German; Frechette, Joelle

2013-01-01

338

Genetics of amyotrophic lateral sclerosis: an update  

PubMed Central

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder involving both upper motor neurons (UMN) and lower motor neurons (LMN). Enormous research has been done in the past few decades in unveiling the genetics of ALS, successfully identifying at least fifteen candidate genes associated with familial and sporadic ALS. Numerous studies attempting to define the pathogenesis of ALS have identified several plausible determinants and molecular pathways leading to motor neuron degeneration, which include oxidative stress, glutamate excitotoxicity, apoptosis, abnormal neurofilament function, protein misfolding and subsequent aggregation, impairment of RNA processing, defects in axonal transport, changes in endosomal trafficking, increased inflammation, and mitochondrial dysfunction. This review is to update the recent discoveries in genetics of ALS, which may provide insight information to help us better understanding of the disease neuropathogenesis. PMID:23941283

2013-01-01

339

Bilayer Graphene Lateral Contacts for DNA Sequencing  

E-print Network

Translocation of DNA through a nanopore with embedded electrodes is at the centre of new rapid inexpensive sequencing methods which allow distinguishing the four nucleobases by their different electronic structure. However, the subnanometer separation between nucleotides in DNA requires ultra-sharp probes. Here, we propose a device architecture consisting of a nanopore formed in bilayer graphene, with the two layers acting as separate electrical contacts. The 0.34 nm interlayer distance of graphene is ideally suited for electrical coupling to a single nucleobase, avoiding the difficulty of fabricating probes with subnanometer precision. The top and bottom graphene electrodes contact the target molecule from the same lateral side, removing the orders-of-magnitude tunneling current variations between smaller pyrimidine bases and larger purine bases. We demonstrate that incorporating techniques for molecular manipulation enables the proposed device to sequence single-stranded DNA and that it offers even the pros...

He, Yuhui; Scheicher, Ralph H; Taniguchi, Masateru; Kawai, Tomoji

2012-01-01

340

Optical fiber head for providing lateral viewing  

DOEpatents

The head of an optical fiber comprising the sensing probe of an optical heterodyne sensing device includes a planar surface that intersects the perpendicular to axial centerline of the fiber at a polishing angle .theta.. The planar surface is coated with a reflective material so that light traveling axially through the fiber is reflected transverse to the fiber's axial centerline, and is emitted laterally through the side of the fiber. Alternatively, the planar surface can be left uncoated. The polishing angle .theta. must be no greater than 39.degree. or must be at least 51.degree.. The emitted light is reflected from adjacent biological tissue, collected by the head, and then processed to provide real-time images of the tissue. The method for forming the planar surface includes shearing the end of the optical fiber and applying the reflective material before removing the buffer that circumscribes the cladding and the core.

Everett, Matthew J. (Livermore, CA); Colston, Billy W. (Livermore, CA); James, Dale L. (Tracy, CA); Brown, Steve (Livermore, CA); Da Silva, Luiz (Danville, CA)

2002-01-01

341

Motoneuron firing in amyotrophic lateral sclerosis (ALS)  

PubMed Central

Amyotrophic lateral sclerosis is an inexorably progressive neurodegenerative disorder involving the classical motor system and the frontal effector brain, causing muscular weakness and atrophy, with variable upper motor neuron signs and often an associated fronto-temporal dementia. The physiological disturbance consequent on the motor system degeneration is beginning to be well understood. In this review we describe aspects of the motor cortical, neuronal, and lower motor neuron dysfunction. We show how studies of the changes in the pattern of motor unit firing help delineate the underlying pathophysiological disturbance as the disease progresses. Such studies are beginning to illuminate the underlying disordered pathophysiological processes in the disease, and are important in designing new approaches to therapy and especially for clinical trials. PMID:25294995

de Carvalho, Mamede; Eisen, Andrew; Krieger, Charles; Swash, Michael

2014-01-01

342

Mechanical contributions to chronic lateral ankle instability.  

PubMed

Lateral ankle sprains are one of the most common athletic injuries. Even more concerning is the high recurrence rate after an initial sprain. The development of repetitive ankle sprains and persistent symptoms after injury has been termed chronic ankle instability (CAI). One of the purported causes of CAI is mechanical ankle instability (MAI).MAI results in abnormal ankle mechanics. Both hypermobility and hypomobility may change a joint's axis of rotation and result in abnormal joint mechanics. The role of hypermobility, or laxity, has been examined extensively in the literature, but more recently the role of hypomobility has also been examined. There may be a relationship between the two, with implications at the talocrural, subtalar, and inferior tibiofibular joints.Assessment and treatment should focus on both hypermobility and hypomobility and although injury may seem to be isolated to the talocrural joint, the inferior tibiofibular and subtalar joints should also be thoroughly examined. PMID:16526836

Hubbard, Tricia J; Hertel, Jay

2006-01-01

343

The never-married in later life.  

PubMed

Sources or consequences of singlehood are analyzed for the 162 never-married persons aged 50 and over from the six years of the NORC General Social Surveys. Highly-educated older women are most likely to remain single, but family background was not a predictor. Although the never-married find life more exciting than other marital statuses among younger (25 to 49) respondents, this reverses in later life. The never-married are also less happy than the married, and only slightly happier than the widowed and divorced. The characteristic that best explains their relative unhappiness is greater dissatisfaction with family life. The lower well-being of the never-married is attributable either to changes accompanying aging which lessen the viability of single life styles, or to less support of single living among current older cohorts. PMID:512306

Ward, R A

1979-11-01

344

EAS-BUAP: Lateral Distribution and Performance  

NASA Astrophysics Data System (ADS)

We describe the operation and performance of the first stage of the EAS-UAP extensive air shower array, as a detector of very high energy cosmic rays (Eo > 1014eV) after one year of operation. The array is located at the Campus of Puebla University, 2200 m above sea level. It consists of 10 liquid scintillator detectors, each with an active surface of 1 m2 and a detector spacing of 20 m in a square grid. One Auger Water Cherenkov detector is also included as part of the array. In this report we discuss the stability, the calibration and lateral distribution function reconstruction capabilities of the detector array. We also present the analysis of the shower size spectrum. In addition, the main characteristics of this array allow us to use it as an educational and training facility.

Salazar, H.; Martinez, O.; Cotzomi, J.; Moreno, E.; Aguilar, S.; Villaseńor, L.

2003-07-01

345

Pay Me Now or Pay Me Later: 10 Years Later and Have We Seen Any Change?  

ERIC Educational Resources Information Center

It has been nearly a decade since the 1996 Surgeon General?s Report (SGR) on "Physical Activity and Health" (United States Department of Health and Human Services [USDHHS], 1996). It is time that people stop and reflect on this historic report and begin the assessment process--are people paying now or will they continue to pay later? This…

Cone, Stephen L.

2004-01-01

346

Lateral interactions in the outer retina  

PubMed Central

Lateral interactions in the outer retina, particularly negative feedback from horizontal cells to cones and direct feed-forward input from horizontal cells to bipolar cells, play a number of important roles in early visual processing, such as generating center-surround receptive fields that enhance spatial discrimination. These circuits may also contribute to post-receptoral light adaptation and the generation of color opponency. In this review, we examine the contributions of horizontal cell feedback and feed-forward pathways to early visual processing. We begin by reviewing the properties of bipolar cell receptive fields, especially with respect to modulation of the bipolar receptive field surround by the ambient light level and to the contribution of horizontal cells to the surround. We then review evidence for and against three proposed mechanisms for negative feedback from horizontal cells to cones: 1) GABA release by horizontal cells, 2) ephaptic modulation of the cone pedicle membrane potential generated by currents flowing through hemigap junctions in horizontal cell dendrites, and 3) modulation of cone calcium currents (ICa) by changes in synaptic cleft proton levels. We also consider evidence for the presence of direct horizontal cell feed-forward input to bipolar cells and discuss a possible role for GABA at this synapse. We summarize proposed functions of horizontal cell feedback and feed-forward pathways. Finally, we examine the mechanisms and functions of two other forms of lateral interaction in the outer retina: negative feedback from horizontal cells to rods and positive feedback from horizontal cells to cones. PMID:22580106

Thoreson, Wallace B.; Mangel, Stuart C.

2012-01-01

347

[Lateralization of the epileptic process and psychology].  

PubMed

In a group of 70 patients with a unilateral epileptic process in the temporal limbic structures, localized in the left half of the brain in 38 patients (26 men, 12 women) and in the right half of the brain in 32 patients (17 men, 15 women) the lateralization of motor functions, asymmetry of emotional mimicry, conjugated deviation of the eye bulbs, intellect, memory, psychomotor rate and personality (laterality test of Mat?jcek--Zlab, Wechsler's intellect and memory scale, Benton, Stroop, VAROS, SUPOS, DSF, Washington Psychosocial--Seizure Inventory WPSI was investigated. Patient with a left-sided epileptic process had only insignificantly lower contact with psychiatry (31.6% as compared with 40.6%). Significantly lower contacts with psychiatry were recorded in 35 patients with a predominance of emotional mimicry (while smiling) on the left (25.0% as compared with 47.1%, p less than 0.05) and particularly significantly low in 18 patients with a combination of signs left-sided epileptic process + predominance of emotional mimicry on the left + deviation of the eyeballs on the right (mathematical stimulus) + genotypical righthandedness (16.7% as compared with 42.3%, p less than 0.025). Men with a left-sided epileptic process displayed a significantly greater anxiety, in women this trend was only indicated. Four women with a left-sided epileptic process anticipating regulation of behaviour was typical, for women with a right-sided epileptic process lower autoregulating inhibitions. A left-sided epileptic process had significantly more often a favourable course of epilepsy (in 65.8% as compared with 25.0%, p less than 0.005). In psychological tests, however, the differentiating criteria were much more than the course of the disease invalid pension, contact with psychiatry and subjective need of assistance from a psychiatrist or psychologist. PMID:2731273

Preiss, J; Kristof, M

1989-04-01

348

Variable Left-hemisphere Language and Orthographic Lateralization Reduces Right-hemisphere Face Lateralization.  

PubMed

It is commonly believed that, in right-handed individuals, words and faces are processed by distinct neural systems: one in the left hemisphere (LH) for words and the other in the right hemisphere (RH) for faces. Emerging evidence suggests, however, that hemispheric selectivity for words and for faces may not be independent of each other. One recent account suggests that words become lateralized to the LH to interact more effectively with language regions, and subsequently, as a result of competition with words for representational space, faces become lateralized to the RH. On this interactive account, left-handed individuals, who as a group show greater variability with respect to hemispheric language dominance, might be expected to show greater variability in their degree of RH lateralization of faces as well. The current study uses behavioral measures and ERPs to compare the hemispheric specialization for both words and faces in right- and left-handed adult individuals. Although both right- and left-handed groups demonstrated LH over RH superiority in discrimination accuracy for words, only the right-handed group demonstrated RH over LH advantage in discrimination accuracy for faces. Consistent with this, increased right-handedness was related to an increase in RH superiority for face processing, as measured by the strength of the N170 ERP component. Interestingly, the degree of RH behavioral superiority for face processing and the amplitude of the RH N170 for faces could be predicted by the magnitude of the N170 ERP response to words in the LH. These results are discussed in terms of a theoretical account in which the typical RH face lateralization fails to emerge in individuals with atypical language lateralization because of weakened competition from the LH representation of words. PMID:25390197

Dundas, Eva M; Plaut, David C; Behrmann, Marlene

2015-05-01

349

Lateral shift in one-dimensional quasiperiodic chiral photonic crystal  

NASA Astrophysics Data System (ADS)

We investigate the lateral shift of a one-dimensional quasiperiodic photonic crystal consisting of chiral and conventional dielectric materials. The effect of structural irregularity on lateral shift is evaluated by stationary-phase approach. Our results show that the lateral shift can be modulated by varying the structural irregularity in quasiperiodic structure. Besides, the position of peak in lateral shift spectrum stays sensitive to the chiral factor of chiral materials. In comparison with that of periodic structure, quasiperiodic structure provides an extra degree of freedom to manipulate the lateral shift.

Da, Jian; Mo, Qi; Cheng, Yaokun; Liu, Taixiang

2015-02-01

350

Direction selectivity in the middle lateral and lateral (ML and L) visual areas in the California ground squirrel  

Microsoft Academic Search

Extracellular recordings obtained from the extrastriate cortex of the California ground squirrel, a diurnal sciurid, show that large receptive fields and a strong direction selectivity are present in the middle lateral area (ML) and the lateral area (L), located laterally to V2 and V3. Direction selectivity was tested by presenting stimuli of varying dimensions, shapes and speeds at different locations

Monica Paolini; Martin I. Sereno

1998-01-01

351

Laterality Patterns of Brain Functional Connectivity: Gender Effects  

PubMed Central

Lateralization of brain connectivity may be essential for normal brain function and may be sexually dimorphic. Here, we study the laterality patterns of short-range (implicated in functional specialization) and long-range (implicated in functional integration) connectivity and the gender effects on these laterality patterns. Parallel computing was used to quantify short- and long-range functional connectivity densities in 913 healthy subjects. Short-range connectivity was rightward lateralized and most asymmetrical in areas around the lateral sulcus, whereas long-range connectivity was rightward lateralized in lateral sulcus and leftward lateralizated in inferior prefrontal cortex and angular gyrus. The posterior inferior occipital cortex was leftward lateralized (short- and long-range connectivity). Males had greater rightward lateralization of brain connectivity in superior temporal (short- and long-range), inferior frontal, and inferior occipital cortices (short-range), whereas females had greater leftward lateralization of long-range connectivity in the inferior frontal cortex. The greater lateralization of the male's brain (rightward and predominantly short-range) may underlie their greater vulnerability to disorders with disrupted brain asymmetries (schizophrenia, autism). PMID:21878483

Tomasi, Dardo; Volkow, Nora D.

2012-01-01

352

Lateral patellofemoral ligament reconstruction using a free gracilis autograft.  

PubMed

Medial patellofemoral instability is a rare, disabling condition that is often associated with the wrong indication for lateral retinacular release or overcorrection with medializing tibial tubercle osteotomy. It is an even less common complication after total knee arthroplasty (TKA). The lateral patellofemoral ligament is an important lateral stabilizer of the patella against medial subluxation or dislocation. Until now, no report in the literature has described lateral patellofemoral ligament reconstruction with a free gracilis tendon autograft. Furthermore, there has not been a single case report of lateral patellofemoral ligament reconstruction after TKA. The authors describe a novel technique for reconstruction of the lateral patellofemoral ligament in a symptomatic medial subluxated patella resulting from TKA and extended lateral release in a 62-year-old patient. The result 1 year postoperatively was deemed successful. Clinically, the patella was stable, with correct tracking, and radiologically the patella was correctly positioned. With a technique similar to that used for the medial patellofemoral ligament, the lateral patellofemoral ligament can be reconstructed with a gracilis tendon autograft to permit stabilization independent of resting scar tissue of the lateral retinaculum. This operation can be performed in a minimally invasive way, without opening the joint, therefore decreasing the risk of joint infection. The authors showed a successful clinical and radiologic outcome 1 year after lateral patellofemoral ligament reconstruction in a patient with medial patellar instability after TKA and lateral release. PMID:24992066

Borbas, Paul; Koch, Peter P; Fucentese, Sandro F

2014-07-01

353

Multiplex lateral flow immunoassay for mycotoxin determination.  

PubMed

A new lateral flow immunoassay (LFA) is proposed for qualitative and/or semiquantitative determination of aflatoxin B1 (AFB1), zearalenone (ZEA), deoxynivalenol (DON), and their analogues (AFs, ZEAs, DONs) in cereal samples. Each of the mycotoxin specific antibody was class specific and there was no cross reactivity to other groups of compounds. The visual limits of detection (vLOD) of the strip were 0.03, 1.6, and 10 ?g/kg for AFB1, ZEA and DON, respectively. The calculated limits of detection (cLOD) were 0.05, 1, and 3 ?g/kg, respectively. Meanwhile the cutoff values were achieved at 1, 50, and 60 ?g/kg for AFB1, ZEA and DON, respectively. Recoveries ranged from 80% to 122% and RSD from 5% to 20%. Both the vLOD and cLOD for the three mycotoxins were lower than the EU maximum levels. Analysis of naturally contaminated maize samples resulted in a good agreement between the multiplex LFA and LC-MS/MS (100% for DONs and AFs, and 81% for ZEAs). Careful analysis of the results further explained the general overestimation of LFA compared to chromatographic methods for quantification of mycotoxins. PMID:24745689

Song, Suquan; Liu, Na; Zhao, Zhiyong; Njumbe Ediage, Emmanuel; Wu, Songling; Sun, Changpo; De Saeger, Sarah; Wu, Aibo

2014-05-20

354

Risk factors for amyotrophic lateral sclerosis  

PubMed Central

Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease. It is typically fatal within 2–5 years of symptom onset. The incidence of ALS is largely uniform across most parts of the world, but an increasing ALS incidence during the last decades has been suggested. Although recent genetic studies have substantially improved our understanding of the causes of ALS, especially familial ALS, an important role of non-genetic factors in ALS is recognized and needs further study. In this review, we briefly discuss several major genetic contributors to ALS identified to date, followed by a more focused discussion on the most commonly examined non-genetic risk factors for ALS. We first review factors related to lifestyle choices, including smoking, intake of antioxidants, physical fitness, body mass index, and physical exercise, followed by factors related to occupational and environmental exposures, including electromagnetic fields, metals, pesticides, ?-methylamino-L-alanine, and viral infection. Potential links between ALS and other medical conditions, including head trauma, metabolic diseases, cancer, and inflammatory diseases, are also discussed. Finally, we outline several future directions aiming to more efficiently examine the role of non-genetic risk factors in ALS. PMID:25709501

Ingre, Caroline; Roos, Per M; Piehl, Fredrik; Kamel, Freya; Fang, Fang

2015-01-01

355

Laterally graded multilayer double-monochromator.  

SciTech Connect

The authors describe a tunable multilayer monochromator with an adjustable bandpass to be used for reflectivity and grazing incidence diffraction studies on surfaces at energies near 10 keV. Multilayers have a bandpass typically 100 times larger than the Si(111) reflection, and by using multilayers an experimenter can significantly increase data collection rates over those available with a Si monochromator. The transmission through 1 and 2 laterally graded multilayer (LGML) reflections was recorded versus photon energy. The identical LGMLs were comprised of 60 bilayers of W and C on 100 x 25 x 3 mm float glass with a bilayer spacing varying from 35 to 60 {angstrom}. The average gradient was 0.27 {angstrom}/mm along the long dimension. The rms deviation of the data for the bilayer spacing from a linear fit was 0.36 {angstrom}. Data were obtained for a nondispersive ({+-}) double-multilayer arrangement. The relative bandpass width (FWHM) when the two multilayers exposed the same bilayer spacing was measured to be 2.2% with a transmission of 78.7 {+-} 1.6%. This value is consistent with the transmission of 88.9% that they also measured for a single LGML at HASYLAB beamline D4. The bandpass was tunable in the range 1.1% to 2.2%.

Als-Nielsen, J.; Erdmann, J.; Gaarde, P.; Krasnicki, S.; Liu, C.; Macrander, A. T.; Maj, J.; Mancini, D.

1999-09-01

356

Chromogranin peptides in amyotrophic lateral sclerosis.  

PubMed

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder which primarily affects motor neurons. Eight cases of ALS and seven control cases were studied with semiquantitative immunocytochemistry for chromogranin A, chromogranin B and secretogranin II that are soluble constituents of large dense core vesicles, synaptophysin as a membrane protein of small synaptic vesicles and superoxide dismutase 1. Among the chromogranin peptides, the number and staining intensity of motor neurons was highest for chromogranin A. In ALS, the staining intensity for chromogranin peptides and synaptophysin was significantly lower in the ventral horn of ALS patients due to a loss in immunoreactive motor neurons, varicose fibers and varicosities. For all chromogranins, the remaining motor neurons displayed a characteristic staining pattern consisting of an intracellular accumulation of immunoreactivity with a high staining intensity. Confocal microscopy of motor neurons revealed that superoxide dismutase 1-immunopositive intracellular aggregates also contained chromogranin A, chromogranin B and secretogranin II. These findings indicate that there is a loss of small and large dense core vesicles in presynaptic terminals. The intracellular co-occurrence of superoxide dismutase 1 and chromogranins may suggest a functional interaction between these proteins. This study should prompt further experiments to elucidate the role of chromogranins in ALS patients. PMID:18721831

Schrott-Fischer, A; Bitsche, M; Humpel, C; Walcher, C; Maier, H; Jellinger, K; Rabl, W; Glueckert, R; Marksteiner, J

2009-01-01

357

Early environment influences later performance in fishes.  

PubMed

Conditions fish encounter during embryogenesis and early life history can leave lasting effects not only on morphology, but also on growth rate, life-history and behavioural traits. The ecology of offspring can be affected by conditions experienced by their parents and mother in particular. This review summarizes such early impacts and their ecological influences for a variety of teleost species, but with special reference to salmonids. Growth and adult body size, sex ratio, egg size, lifespan and tendency to migrate can all be affected by early influences. Mechanisms behind such phenotypically plastic impacts are not well known, but epigenetic change appears to be one central mechanism. The thermal regime during development and incubation is particularly important, but also early food consumption and intraspecific density can all be responsible for later life-history variation. For behavioural traits, early experiences with effects on brain, sensory development and cognition appear essential. This may also influence boldness and other social behaviours such as mate choice. At the end of the review, several issues and questions for future studies are given. PMID:24961386

Jonsson, B; Jonsson, N

2014-08-01

358

Treatment algorithm for chronic lateral ankle instability  

PubMed Central

Summary Introduction: ankle sprains are a common sports-related injury. A 20% of acute ankle sprains results in chronic ankle instability, requiring surgery. Aim of this paper is to report the results of a series of 38 patients treated for chronic lateral ankle instability with anatomic reconstruction. Materials and methods: thirty-eight patients were enrolled in the study. Seventeen patients underwent a surgical repair using the Brostrom-modified technique, while the remaining underwent anatomic reconstruction with autologous or allogenic graft. Results: at a mean follow-up of 5 years the AOFAS score improved from 66.1 ± 5.3 to 92.2 ± 5.6. Discussion: the findings of this study confirm that anatomic reconstruction is an effective procedure with satisfactory subjective and objective results which persist at long-term follow-up along with a low complication rate. No differences, in term of clinical and functional outcomes, were observed between the Brostrom-modified repair and the anatomic reconstruction technique. Level of evidence: level IV. PMID:25767783

Giannini, Sandro; Ruffilli, Alberto; Pagliazzi, Gherardo; Mazzotti, Antonio; Evangelisti, Giulia; Buda, Roberto; Faldini, Cesare

2014-01-01

359

Lateral gene transfer in the subsurface  

SciTech Connect

Lateral gene transfer (LGT) is an important adaptive mechanism among prokaryotic organisms. This mechanism is particularly important for the response of microorganisms to changing environmental conditions because it facilitates the transfer of a large number of genes and their rapid expression. Together the transferred genes promote rapid genetic and metabolic changes that may enhance survival to newly established and sometimes hostile environmental conditions. The goal of our project was to examine if and how LGT enhances microbial adaptation to toxic heavy metals in subsurface environments that had been contaminated by mixed wastes due to activities associated with the production of nuclear energy and weapons. This task has been accomplished by dividing the project to several sub-tasks. Thus, we: (1) Determined the level of resistance of subsurface bacterial isolates to several toxic metals, all identified as pollutants of concern in subsurface environments; (2) Designed, tested, and applied, a molecular approach that determined whether metal resistance genes had evolved by LGT among subsurface bacteria; and (3) Developed a DNA hybridization array for the identification of broad host range plasmids and of metal resistance plasmids. The results are briefly summarized below with references to published papers and manuscripts in preparation where details about our research can be found. Additional information may be found in copies of our published manuscripts and conference proceedings, and our yearly reports that were submitted through the RIMS system.

Barkay, Tamar; Sobecky, Patricia

2007-08-27

360

Mitochondrial Dysfunction in Amyotrophic Lateral Sclerosis  

PubMed Central

The etiology of motor neuron degeneration in amyotrophic lateral sclerosis (ALS) remains to be better understood. Based on the studies from ALS patients and transgenic animal models, it is believed that ALS is likely to be a multifactorial and multisystem disease. Many mechanisms have been postulated to be involved in the pathology of ALS, such as oxidative stress, glutamate excitotoxicity, mitochondrial damage, defective axonal transport, glia cell pathology and aberrant RNA metabolism. Mitochondria, which play crucial roles in excitotoxicity, apoptosis and cell survival, have shown to be an early target in ALS pathogenesis and contribute to the disease progression. Morphological and functional defects in mitochondria were found in both human patients and ALS mice overexpressing mutant SOD1. Mutant SOD1 was found to be preferentially associated with mitochondria and subsequently impair mitochondrial function. Recent studies suggest that axonal transport of mitochondria along microtubules and mitochondrial dynamics may also be disrupted in ALS. These results also illustrate the critical importance of maintaining proper mitochondrial function in axons and neuromuscular junctions, supporting the emerging “dying-back” axonopathy model of ALS. In this review, we will discuss how mitochondrial dysfunction has been linked to the ALS variants of SOD1 and the mechanisms by which mitochondrial damage contributes to the disease etiology. PMID:19715760

Shi, Ping; Gal, Jozsef; Kwinter, David M.; Liu, Xiaoyan; Zhu, Haining

2009-01-01

361

Does cerebral lateralization develop? A study using functional transcranial Doppler ultrasound assessing lateralization for language production and visuospatial memory  

PubMed Central

In the majority of people, language production is lateralized to the left cerebral hemisphere and visuospatial skills to the right. However, questions remain as to when, how, and why humans arrive at this division of labor. In this study, we assessed cerebral lateralization for language production and for visuospatial memory using functional transcranial Doppler ultrasound in a group of 60 typically developing children between the ages of six and 16 years. The typical pattern of left-lateralized activation for language production and right-lateralized activation for visuospatial memory was found in the majority of the children (58%). No age-related change in direction or strength of lateralization was found for language production. In contrast, the strength of lateralization (independent of direction) for visuospatial memory function continued to increase with age. In addition, boys showed a trend for stronger right-hemisphere lateralization for visuospatial memory than girls, but there was no gender effect on language laterality. We tested whether having language and visuospatial functions in the same hemisphere was associated with poor cognitive performance and found no evidence for this “functional crowding” hypothesis. We did, however, find that children with left-lateralized language production had higher vocabulary and nonword reading age-adjusted standard scores than other children, regardless of the laterality of visuospatial memory. Thus, a link between language function and left-hemisphere lateralization exists, and cannot be explained in terms of maturational change. PMID:22741100

Groen, Margriet A; Whitehouse, Andrew J O; Badcock, Nicholas A; Bishop, Dorothy V M

2012-01-01

362

Determination of lateral-stability derivatives and transfer-function coefficients from frequency-response data for lateral motions  

NASA Technical Reports Server (NTRS)

A method is presented for determining the lateral-stability derivatives, transfer-function coefficients, and the modes for lateral motion from frequency-response data for a rigid aircraft. The method is based on the application of the vector technique to the equations of lateral motion, so that the three equations of lateral motion can be separated into six equations. The method of least squares is then applied to the data for each of these equations to yield the coefficients of the equations of lateral motion from which the lateral-stability derivatives and lateral transfer-function coefficients are computed. Two numerical examples are given to demonstrate the use of the method.

Donegan, James J; Robinson, Samuel W , Jr; Gates, Ordway, B , jr

1955-01-01

363

Venous thromboembolism in amyotrophic lateral sclerosis  

PubMed Central

Objective: To prospectively assess the incidence of both symptomatic and asymptomatic venous thromboembolism (VTE) in patients with amyotrophic lateral sclerosis (ALS) and to identify risk factors. Methods: Fifty outpatients with ALS were recruited consecutively and prospectively evaluated with bilateral venous duplex ultrasonography (VDU) of the proximal leg veins at enrollment and 6 and 12 months. The primary outcome measure was clinically important VTE, defined as asymptomatic proximal deep vein thrombosis (DVT) by screening VDU, symptomatically proven DVT or pulmonary embolism (PE), or fatal PE. For each patient, person-days of follow-up were recorded from enrollment until the date of VTE, death, loss to follow-up, or final 12-month visit. Results: During the 1-year follow-up period, VTE was detected in 4 patients (1 symptomatic DVT, 1 symptomatic PE, and 2 asymptomatic DVTs) over 13,011 person-days of follow-up, representing an 11.2% 1-year incidence. Subjects with leg-onset ALS or significant leg weakness had a 1-year VTE incidence rate of 35.8% and 35.5%, respectively. VTE risk was significantly increased for those patients with decreased lower extremity Revised ALS Functional Rating Scale subscore (p = 0.03), decreased Lower Extremity Activity Scale score (p = 0.02), and decreased average lower limb Medical Research Council scale strength score (p = 0.03). Conclusions: Our data suggest that clinically important VTE is common in patients with ALS, particularly those with leg weakness and reduced mobility. Given these results, the potential benefits of routine VTE screening and primary prophylaxis in high-risk patients with ALS with leg weakness should be explored in future studies. In the meantime, physicians should have a low threshold for considering VTE in patients with ALS with leg weakness. PMID:24727309

Gladman, Matthew; DeHaan, Melanie; Pinto, Hanika; Geerts, William

2014-01-01

364

Lateral Shock of the R Aquarii Jet  

NASA Technical Reports Server (NTRS)

The R Aqr jet was observed with the VLA B-configuration at two epochs separated by approximately 13.2 yr. Comparison of the resulting 6 cm continuum images show that the radio jet has undergone a lateral counterclockwise rotation of approximately 6 deg-12 deg on the plane of the sky. The model of jet parcels on independent trajectories is difficult to reconcile with these observations and leads us to consider a path-oriented jet (i.e., younger parcels follow the same path as older parcels). Comparison of the most recent radio image with a nearly contemporaneous HST/FOC ultraviolet image at approximately 2330 Angstroms suggests that the ultraviolet emission lies along the leading side of the rotating radio jet. In conjunction with a proper motion analysis of the jet material that yields empirical space-velocity and resulting acceleration-magnitude relationships as a function of distance from the central source, we evaluate the observational results in terms of a schematic model in which the jet emission consists of plane-parallel isothermal shocks along the leading edge of rotation. In such a radiating shock, the ultraviolet-emitting region is consistent with the adiabatic region in the form of a high-temperature, low-density sheath that surrounds the cooled postshock radio-emitting region. Within the context of the schematic model, we obtain the temperatures, densities, and pressures within the preshock, adiabatic, and postshock regions as a function of distance from the central source; the physical parameters so derived compare favorably to previously published estimates. We obtain a total jet mass of 3.1 x 10(exp -5) solar mass and an age of approximately 115 yr. We evaluate the model in the context of its density-boundary condition, its applicability to an episodic or quasi-continuous jet, and angular momentum considerations.

Hollis, J. M.; Pedelty, J. A.; Kafatos, M.

1997-01-01

365

Measuring lateral shuffle and side cut performance.  

PubMed

Lateral shuffle and side cut (SSC) movements are defensive basketball movements where movement speed is critical to performance. The purpose of this study was to compare SSC data obtained using timing lights with motion capture system data and to determine the most appropriate method for measuring SSC performance. Shuffle time data were recorded using both timing lights and a motion capture system while 9 male subjects performed 2 different SSC movement sets, with and without controlling for arm movements, which may influence performance times. Shuffle and side cut times and SSC displacements were used to calculate mean shuffle velocity for each trial. The SEs for the motion capture system were estimated for SSC times (± 4.2 milliseconds; ~0.24% of mean shuffle time) and velocities (± 5.5 mm · s; ~0.24% of mean shuffle velocity), respectively, indicating high levels of precision. Timing light movement time variability was significantly higher during the uncontrolled (SD = 42 milliseconds) when compared with the controlled (SD = 9 milliseconds, p < 0.001) condition, indicating a significant reduction in variability by controlling non-performance-related variability such as arm movement. A significant positive correlation was found between SSC time and SSC displacement (r = 0.42) indicating that performance times were dependent on displacement. Furthermore, the variance in motion-captured SSC velocity was significantly smaller than the variance in velocity determined using timing lights (p < 0.05). We concluded that motion-captured SSC velocity data reduced systematic errors and non-performance-related movement variability and, therefore, was better able to reflect true performance. As true performance variability in human movement provides important information, the presented method for calculating SSC velocity in this study is recommended for assessing SSC performance. PMID:23439340

Whitting, John W; de Melker Worms, Jonathan L A; Maurer, Christian; Nigg, Sandro R; Nigg, Benno M

2013-11-01

366

Efferent connections of the lateral cortex of the lizard Gekko gecko: evidence for separate origins of medial and lateral pathways from the lateral cortex to the hypothalamus.  

PubMed

The lateral cortex of the lizard Gekko gecko is composed of three parts: a dorsal and ventral part located rostrally and a posterior part located caudally. In order to obtain detailed information about the efferent connections of these lateral cortex subdivisions, iontophoretic injections of the anterograde tracers Phaseolus vulgaris leucoagglutinin and biotinylated dextran were made in the various parts. The main projection from the dorsal part terminates in the caudal part of the medial cortex. Other cortical projections were noted to the ipsi- and contralateral lateral cortex, the large-celled part of the medial cortex, and the dorsal cortex. Additional fibers were found bilaterally in the anterior olfactory nucleus and the external amygdaloid nucleus. The ventral part of the lateral cortex projects mainly to the ipsilateral, posterior part of the dorsal ventricular ridge and the external amygdaloid nucleus. Minor contralateral projections to these nuclei were also found. Other projections were observed to travel to the caudal part of the medial cortex, to the nucleus sphericus, and bilaterally to the lateral cortex and the anterior olfactory nucleus. The posterior part of the lateral cortex has similar efferent connections as the dorsal part and should be regarded as the caudal continuation of the dorsal part. Because previous studies have shown that the medial cortex and the amygdaloid complex project to different hypothalamic areas, we conclude that the dorsal and ventral parts of the lateral cortex transmit olfactory information to separate hypothalamic areas that are probably involved with different types of behavior. PMID:7535810

Hoogland, P V; Vermeulen-Vanderzee, E

1995-02-13

367

Lateral position detection and control for friction stir systems  

DOEpatents

Friction stir methods are disclosed for processing at least one workpiece using a rotary tool with rotating member for contacting and processing the workpiece. The methods include oscillating the rotary tool laterally with respect to a selected propagation path for the rotating member with respect to the workpiece to define an oscillation path for the rotating member. The methods further include obtaining force signals or parameters related to the force experienced by the rotary tool at least while the rotating member is disposed at the extremes of the oscillation. The force signals or parameters associated with the extremes can then be analyzed to determine a lateral position of the selected path with respect to a target path and a lateral offset value can be determined based on the lateral position. The lateral distance between the selected path and the target path can be decreased based on the lateral offset value.

Fleming, Paul (Boulder, CO); Lammlein, David H. (Houston, TX); Cook, George E. (Brentwood, TN); Wilkes, Don Mitchell (Nashville, TN); Strauss, Alvin M. (Nashville, TN); Delapp, David R. (Ashland City, TN); Hartman, Daniel A. (Fairhope, AL)

2011-11-08

368

Lateral position detection and control for friction stir systems  

DOEpatents

An apparatus and computer program are disclosed for processing at least one workpiece using a rotary tool with rotating member for contacting and processing the workpiece. The methods include oscillating the rotary tool laterally with respect to a selected propagation path for the rotating member with respect to the workpiece to define an oscillation path for the rotating member. The methods further include obtaining force signals or parameters related to the force experienced by the rotary tool at least while the rotating member is disposed at the extremes of the oscillation. The force signals or parameters associated with the extremes can then be analyzed to determine a lateral position of the selected path with respect to a target path and a lateral offset value can be determined based on the lateral position. The lateral distance between the selected path and the target path can be decreased based on the lateral offset value.

Fleming, Paul; Lammlein, David H.; Cook, George E.; Wilkes, Don Mitchell; Strauss, Alvin M.; Delapp, David R.; Hartman, Daniel A.

2012-06-05

369

Artificial lateral line with biomimetic neuromasts to emulate fish sensing.  

PubMed

Hydrodynamic imaging using the lateral line plays a critical role in fish behavior. To engineer such a biologically inspired sensing system, we developed an artificial lateral line using MEMS (microelectromechanical system) technology and explored its localization capability. Arrays of biomimetic neuromasts constituted an artificial lateral line wrapped around a cylinder. A beamforming algorithm further enabled the artificial lateral line to image real-world hydrodynamic events in a 3D domain. We demonstrate that the artificial lateral line system can accurately localize an artificial dipole source and a natural tail-flicking crayfish under various conditions. The artificial lateral line provides a new sense to man-made underwater vehicles and marine robots so that they can sense like fish. PMID:20061601

Yang, Yingchen; Nguyen, Nam; Chen, Nannan; Lockwood, Michael; Tucker, Craig; Hu, Huan; Bleckmann, Horst; Liu, Chang; Jones, Douglas L

2010-03-01

370

Non-destructive Characterizing of Lateral Doping Effects  

NASA Astrophysics Data System (ADS)

As channel lengths decrease, device performance becomes increasingly sensitive to lateral doping effects. We report on methods of non-contact measurement of lateral diffusion and implant straggle using a combination of a bar mask pattern and Carrier Illumination™ measurements, in which one laser beam generates excess carriers and a second laser beam reflects from the excess carrier distribution. Doped region width is extracted from measurements in structures with a range of pitches and fills from 0 to 100%. The method may be applied to both pre- and post-annealed structures, with orthogonal bar patterns used to determine the vector components of lateral doping. Lateral resolution of 0.5 nm is demonstrated. Both vertical and lateral diffusion distance are obtained. Data presented shows that the ratio of lateral to vertical diffusion depends on implant and anneal conditions. Measurements of high-current single-wafer implants show implant angle uniformity of better than ±1°.

Borden, P.; Budiarto, E.; Felch, S.; Graoui, H.

2005-09-01

371

Modified obtuse-angled lateral exposure of the calcaneum  

Microsoft Academic Search

Objective: The objective of this study is to compare the incidence of post-operative skin healing problems between the classic extensile lateral calcaneal approach and a modified obtuse-angle lateral exposure during the period 1994–2003.Methods: The classic extensile lateral calcaneal approach as described in the literature was (used in 55 cases of calcaneal fractures), while the obtuse-angled approach (used in other 39

Tarek Hussain; Husain Al-Mutairi; Sabrine Al-Zamel; Waleed Al-Tunaib

2004-01-01

372

Development of the lateral line system in the shovelnose sturgeon.  

PubMed

The lateral line systems of aquatic amphibians and all chondrichthyan and osteichthyan fish present a similar array of mechanoreceptors. However, electroreceptors, the second major component of the lateral line system, have clearly undergone more significant evolutionary change. Chondrichthyans and non-neopterygian fish possess primitive ampullary organ electroreceptors, whereas significantly different 'new' ampullary organs and tuberous electroreceptors are found in a few groups of teleosts (mormyrids, gymnotids and some catfish). The pairing of mechano- and electroreceptors in the lateral line system, as well as the morphologically and physiologically distinct electroreceptors of teleosts have inspired several recent studies on the origin and evolution of the lateral line receptors. We described the development of the lateral line system in sturgeon (Scaphirhynchus platorynchus) as part of an outgroup analysis of lateral line development in three taxa: vertebrates that have both mechanoreceptive neuromasts and primitive electroreceptors; neopterygian fish that only have mechanoreceptors; and teleosts that have re-evolved new electroreceptors. Development in Scaphirhynchus was consistent with previously studied taxa in that the lateral line system developed from a series of six dorsolateral placodes. Interestingly, we found that the octaval placode was bound rostrally and caudally by large placodal fields, out of which the six lateral line placodes arose. This finding supports recent suggestions for a common placodal primordium for all placodes. Each of the six placodes gave rise to the lateral line nerves before elongating into sensory ridges, which contained neuromast primordia. The ampullary organ fields of Scaphirhynchus arose from the lateral zones of the anterodorsal, anteroventral, otic and supratemporal sensory ridges, which is also consistent with recently studied taxa. Comparisons of the lateral line system of Scaphirhynchus and close relatives, Acipenser and Polyodon, indicate that variation in some aspects of lateral line receptor numbers and distribution are related to changes in head morphology and feeding strategy, whereas other changes, such as a reduction in receptor number without a change in placode field size, indicate changes in placode development. PMID:15205543

Gibbs, Melissa A; Northcutt, R Glenn

2004-01-01

373

7. SEGMENT OF LATERAL WITH YUCCA ALONG BANKS, SOUTH OF ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. SEGMENT OF LATERAL WITH YUCCA ALONG BANKS, SOUTH OF 6TH AVENUE (SECTION 10). - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

374

4. SEGMENT OF LATERAL WEST OF C STREET (SECTION 10) ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. SEGMENT OF LATERAL WEST OF C STREET (SECTION 10) ON THE ROCKY MOUNTAIN ARSENAL (RMA). - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

375

24. CULVERT WITH CONCRETE HEADWALL AND SIDEWALLS CARRYING THE LATERAL ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

24. CULVERT WITH CONCRETE HEADWALL AND SIDEWALLS CARRYING THE LATERAL UNDER 8TH AVENUE. - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

376

2. COURSE OF THE LATERAL THROUGH DEL NORTHWEST MAR PARK. ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. COURSE OF THE LATERAL THROUGH DEL NORTHWEST MAR PARK. - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

377

13. TREES ALONG LATERAL SEGMENT AT THE NORTHERN END OF ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

13. TREES ALONG LATERAL SEGMENT AT THE NORTHERN END OF LAKE LADORA. - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

378

8. GENERAL VIEW OF LARGE DIVERSION STRUCTURE ON LATERAL WEST ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. GENERAL VIEW OF LARGE DIVERSION STRUCTURE ON LATERAL WEST OF LOWER DERBY LAKE (SECTION 2). - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

379

The lateral plate mesoderm: a novel source of skeletal muscle.  

PubMed

It has been established in the last century that the skeletal muscle cells of vertebrates originate from the paraxial mesoderm. However, recently the lateral plate mesoderm has been identified as a novel source of the skeletal muscle. The branchiomeric muscles, such as masticatory and facial muscles, receive muscle progenitor cells from both the cranial paraxial mesoderm and lateral plate mesoderm. At the occipital level, the lateral plate mesoderm is the sole source of the muscle progenitors of the dorsolateral neck muscle, such as trapezius and sternocleidomastoideus in mammals and cucullaris in birds. The lateral plate mesoderm requires a longer time for generating skeletal muscle cells than the somites. The myogenesis of the lateral plate is determined early, but not cell autonomously and requires local signals. Lateral plate myogenesis is regulated by mechanisms controlling the cranial myogenesis. The connective tissue of the lateral plate-derived muscle is formed by the cranial neural crest. Although the cranial neural crest cells do not control the early myogenesis, they regulate the patterning of the branchiomeric muscles and the cucullaris muscle. Although satellite cells derived from the cranial lateral plate show distinct properties from those of the trunk, they can respond to local signals and generate myofibers for injured muscles in the limbs. In this review, we key feature in detail the muscle forming properties of the lateral plate mesoderm and propose models of how the myogenic fate may have arisen. PMID:25344670

Pu, Qin; Patel, Ketan; Huang, Ruijin

2015-01-01

380

The split peroneus longus lateral ankle stabilization procedure.  

PubMed

The authors present an interesting approach to lateral ankle stabilization using the peroneus longus tendon. The more commonly utilized procedures for instability of the ankle complex, rationale for use of the peroneus longus tendon, and the details of the split peroneus longus lateral ankle stabilization procedure are presented. When evaluating patients with lateral ankle joint instability, the subtalar joint (STJ) complex needs to be assessed. In addition, the role of STJ instability and its relationship to lateral ankle joint instability are discussed. PMID:8081340

Yu, G V; Lynn, J A; Thornton, D; Choos, J N

1994-01-01

381

Lateral patellotibial ligament reconstruction for medial patellar instability.  

PubMed

Medial patellar instability, though infrequently recognized, can be a disabling complication of a lateral retinacular release. Patients with persistent anterior knee pain and instability after lateral release should be evaluated closely. If evidence of increased medial patellar translation is identified on physical examination, a trial of reverse McConnell taping should be prescribed. If there is noted improvement in symptoms after this taping trial, reconstruction of the lateral patellotibial ligament should be considered. This article details our technique for lateral patellotibial ligament reconstruction using iliotibial band and patellar tendon autografts. PMID:25473603

Sawyer, Gregory A; Cram, Tyler; LaPrade, Robert F

2014-10-01

382

Lateral Patellotibial Ligament Reconstruction for Medial Patellar Instability  

PubMed Central

Medial patellar instability, though infrequently recognized, can be a disabling complication of a lateral retinacular release. Patients with persistent anterior knee pain and instability after lateral release should be evaluated closely. If evidence of increased medial patellar translation is identified on physical examination, a trial of reverse McConnell taping should be prescribed. If there is noted improvement in symptoms after this taping trial, reconstruction of the lateral patellotibial ligament should be considered. This article details our technique for lateral patellotibial ligament reconstruction using iliotibial band and patellar tendon autografts. PMID:25473603

Sawyer, Gregory A.; Cram, Tyler; LaPrade, Robert F.

2014-01-01

383

Lateral Patellofemoral Ligament Reconstruction Using a Quadriceps Tendon Graft.  

PubMed

Medial patellar subluxation (MPS) is normally described after a lateral retinacular release. However, isolated MPS in the absence of a previous lateral release does occur. This type of patellar instability is often overlooked, and a high index of suspicion is needed for appropriate diagnosis and treatment. This report describes a technique developed in response to episodes of isolated MPS. The technique uses a partial-thickness graft from the quadriceps tendon to reconstruct the lateral patellofemoral ligament and provide stability to the lateral side of the patella. PMID:25264506

Saper, Michael G; Shneider, David A

2014-08-01

384

23. VIEW SHOWING SALT RIVER PROJECT CREWS SLIPFORMING LATERAL DURING ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

23. VIEW SHOWING SALT RIVER PROJECT CREWS SLIPFORMING LATERAL DURING REHABILITATION AND BETTERMENT PROGRAM Photographer: unknown. April 1968 - Arizona Canal, North of Salt River, Phoenix, Maricopa County, AZ

385

FILM OPTION CURRICULUM (FOR STUDENTS ENTERING FALL, 2011 OR LATER)  

E-print Network

FILM OPTION CURRICULUM (FOR STUDENTS ENTERING FALL, 2011 OR LATER) NOTE ON REVERSE. GATE REQUIREMENTS FOR FILM OPTION: FILM 100IH ­ Introduction to Film & Photography ...................................................................... 3

Lawrence, Rick L.

386

Gene for a protein capable of enhancing lateral root formation.  

PubMed

Analysis of genes preferentially expressed in hairy roots caused by infection with Agrobacterium rhizogenes has provided insights into the regulation of lateral root formation. A hairy root preferential cDNA, HR7, has been cloned from hairy roots of Hyoscyamus niger. HR7 encodes a novel protein partially homologous to a metallocarboxypeptidase inhibitor and is expressed exclusively in the primordium and base of lateral roots in hairy roots. Overexpression of HR7 in transgenic roots of H. niger dramatically enhances the frequency of lateral root formation. The results of this study indicate that expression of HR7 plays a critical role in initiating lateral root formation. PMID:10356981

Mikami, Y; Horiike, G; Kuroyanagi, M; Noguchi, H; Shimizu, M; Niwa, Y; Kobayashi, H

1999-05-14

387

Serotonergic mechanisms in amyotrophic lateral sclerosis.  

PubMed

Serotonin (5-HT) has been intimately linked with global regulation of motor behavior, local control of motoneuron excitability, functional recovery of spinal motoneurons as well as neuronal maturation and aging. Selective degeneration of motoneurons is the pathological hallmark of amyotrophic lateral sclerosis (ALS). Motoneurons that are preferentially affected in ALS are also densely innervated by 5-HT neurons (e.g., trigeminal, facial, ambiguus, and hypoglossal brainstem nuclei as well as ventral horn and motor cortex). Conversely, motoneuron groups that appear more resistant to the process of neurodegeneration in ALS (e.g., oculomotor, trochlear, and abducens nuclei) as well as the cerebellum receive only sparse 5-HT input. The glutamate excitotoxicity theory maintains that in ALS degeneration of motoneurons is caused by excessive glutamate neurotransmission, which is neurotoxic. Because of its facilitatory effects on glutaminergic motoneuron excitation, 5-HT may be pivotal to the pathogenesis and therapy of ALS. 5-HT levels as well as the concentrations 5-hydroxyindole acetic acid (5-HIAA), the major metabolite of 5-HT, are reduced in postmortem spinal cord tissue of ALS patients indicating decreased 5-HT release. Furthermore, cerebrospinal fluid levels of tryptophan, a precursor of 5-HT, are decreased in patients with ALS and plasma concentrations of tryptophan are also decreased with the lowest levels found in the most severely affected patients. In ALS progressive degeneration of 5-HT neurons would result in a compensatory increase in glutamate excitation of motoneurons. Additionally, because 5-HT, acting through presynaptic 5-HT1B receptors, inhibits glutamatergic synaptic transmission, lowered 5-HT activity would lead to increased synaptic glutamate release. Furthermore, 5-HT is a precursor of melatonin, which inhibits glutamate release and glutamate-induced neurotoxicity. Thus, progressive degeneration of 5-HT neurons affecting motoneuron activity constitutes the prime mover of the disease and its progression and treatment of ALS needs to be focused primarily on boosting 5-HT functions (e.g., pharmacologically via its precursors, reuptake inhibitors, selective 5-HT1A receptor agonists/5-HT2 receptor antagonists, and electrically through transcranial administration of AC pulsed picotesla electromagnetic fields) to prevent excessive glutamate activity in the motoneurons. In fact, 5HT1A and 5HT2 receptor agonists have been shown to prevent glutamate-induced neurotoxicity in primary cortical cell cultures and the 5-HT precursor 5-hydroxytryptophan (5-HTP) improved locomotor function and survival of transgenic SOD1 G93A mice, an animal model of ALS. PMID:16861147

Sandyk, Reuven

2006-07-01

388

Enhanced performance of methamphetamine lateral flow cassettes using an electronic lateral flow reader.  

PubMed

Surface contamination from methamphetamine in meth labs continues to be a problem. We had previously developed a lateral flow assay cassette for field detection of methamphetamine contamination that is commercially available and has been used by a number of groups to assess contamination. This cassette uses the complete disappearance of the test line as an end point for detection of 50 ng/100 cm2 of methamphetamine contamination for surface sampling with cotton swabs. In the present study, we further evaluate the response of the cassettes using an electronic lateral flow reader to measure the intensities of the test and control lines. The cassettes were capable of detecting 0.25 ng/ml for calibration solutions. For 100 cm2 ceramic tiles that were spiked with methamphetamine and wiped with cotton-tipped wooden swabs wetted in assay/sampling buffer, 1 ng/tile was detected using the reader. Semi-quantitative results can be produced over the range 0-10 ng/ml for calibration solutions and 0-25 ng/tile for spiked tiles using either a 4-parameter logistic fit of test line intensity versus concentration or spiked mass or the ratio of the control line to the test line intensity fit to concentration or spiked mass. Recovery from the tiles was determined to be about 30% using the fitted curves. Comparison of the control line to the test line was also examined as a possible visual detection end point and it was found that the control line became more intense than the test line at 0.5 to 1 ng/ml for calibration solutions or 1 to 2 ng/tile for spiked tiles. Thus the lateral flow cassettes for methamphetamine have the potential to produce more sensitive semi-quantitative results if an electronic lateral flow reader is used and can be more sensitive for detection if the comparison of the control line to the test line is used as the visual end point. PMID:25379615

Smith, Jerome P; Sammons, Deborah L; Robertson, Shirley A; Snawder, John E

2015-01-01

389

Atomically flat diamond (111) surface formation by homoepitaxial lateral growth  

Microsoft Academic Search

A process of homoepitaxial growth of diamond (111) films by microwave plasma-enhanced chemical vapor deposition has been investigated characterizing areas by ex-situ atomic force microscopy. The evolution of surface morphology during a lateral growth of (111) diamond was visualized utilizing a mesa structure as a marker. Lateral growth forms atomically flat surfaces, which show atomically flat terraces over several hundred

Norio Tokuda; Hitoshi Umezawa; Sung-Gi Ri; Masahiko Ogura; Kikuo Yamabe; Hideyo Okushi; Satoshi Yamasaki

2008-01-01

390

High-Risk Infants: Auditory Processing Deficits in Later Childhood.  

ERIC Educational Resources Information Center

To determine whether deficits warranting intervention are present in the later functioning of high-risk infants, 22 premature infants who experienced asphyxia or chronic lung disease (CLD) but who had no gross developmental abnormalities were evaluated. Assessments of auditory perception and receptive language ability were made during later

Gilbride, Kathleen E.; And Others

391

Development of the Lateral Line System in the Shovelnose Sturgeon  

Microsoft Academic Search

The lateral line systems of aquatic amphibians and all chondrichthyan and osteichthyan fish present a similar array of mechanoreceptors. However, electroreceptors, the second major component of the lateral line system, have clearly undergone more significant evolutionary change. Chondrichthyans and non-neopterygian fish possess primitive ampullary organ electroreceptors, whereas significantly different ‘new’ ampullary organs and tuberous electroreceptors are found in a few

Melissa A. Gibbs; R. Glenn Northcutt

2004-01-01

392

Role of Lateral Body Bending in Crocodylian Track Making  

Microsoft Academic Search

Locomotion in the alligatorids Caiman and Alligator show ontogenetic changes in gait width, manus orientation, and the amount of lateral body movement. In addition, the trackway of an adult Caiman is narrower than predicted for a semierect position of the limbs based on stance. The narrowness of the Caiman trackway is due to lateral movement of the body during locomotion.

Kenneth Carpenter

2009-01-01

393

The Chinese Calendar of The Later Han Period  

E-print Network

The Chinese Calendar of The Later Han Period Undergraduate Research Opportunities Programme would like to learn some basic knowledge in the Chinese calendar, which is an important part explanations to the Chinese calendar of the Later Han period, Shi Fen Li, and introduce some useful

Aslaksen, Helmer

394

Nursery school personality and political orientation two decades later  

Microsoft Academic Search

The present study reports on the personality attributes of nursery school children who two decades later were reliably stratified along a liberal\\/conservative dimension. An unprecedented analytical opportunity existed to evaluate how the political views of these young adults related to assessments of them when in nursery school, prior to their having become political beings. Preschool children who 20 years later

Jack Block; Jeanne H. Block

2006-01-01

395

The Criminal Histories and Later Offending of Child Pornography Offenders  

Microsoft Academic Search

The likelihood that child pornography offenders will later commit a contact sexual offense is unknown. In the present study, we identified a sample of 201 adult male child pornography offenders using police databases and examined their charges or convictions after the index child pornography offense(s). We also examined their criminal records to identify potential predictors of later offenses: 56% of

Michael C. Seto; Angela W. Eke

2005-01-01

396

The Utility of Proximal-Accretion Stratigraphy in Lateral Moraines  

Microsoft Academic Search

Lateral-moraine stratigraphy is a valuable tool that can be used to constrain the timing and magnitude of alpine glacier fluctuations. Numerous lateral moraines, conventionally thought to have been constructed during the Little Ice Age (LIA), have been shown to be composite landforms that contain multiple till layers deposited by successively larger glacier advances. Organic matter and\\/or tephra sandwiched between the

M. A. Samolczyk; G. Osborn

2010-01-01

397

A lateral optical equilibrium in waveguide-resonator optical force  

E-print Network

A lateral optical equilibrium in waveguide-resonator optical force Varat Intaraprasonk,1@stanford.edu Abstract: We consider the lateral optical force between a resonator and a waveguide, and study the possibility of an equilibrium that occurs solely from the optical force in such system. We prove analytically

Fan, Shanhui

398

An Immersive Media Model of Amyotrophic Lateral Sclerosis  

E-print Network

1 An Immersive Media Model of Amyotrophic Lateral Sclerosis Federico Visi, Duncan Williams, Eduardo.williams, eduardo.miranda}@plymouth.ac.uk giovanni.dothel@gmail.com 1. INTRODUCTION Amyotrophic lateral sclerosis findings, depicting a deep heterogeneity of the disease, are paving the way for a multi

Miranda, Eduardo Reck

399

The lateral distribution of electrons in extensive air showers  

Microsoft Academic Search

Presents new results of an analysis of the lateral distribution of electrons in extensive air showers. It is shown from experimental data that the lateral distribution of electrons is steeper than the NKG function but not as steep as the function proposed by Lagutin et al. (1979). The author also deduces from the experimental measurements a structure function which yields

D. J. van der Walt

1988-01-01

400

Lateral variations in suspended sediment concentration over dunes  

Technology Transfer Automated Retrieval System (TEKTRAN)

The magnitude of the lateral variations in the concentration of suspended sediment over dunes in an alluvial sand-bed channel are poorly known. Characterizing the lateral distributions of suspended sediment is important for understanding its causes and for accurate measurement of the rate of sedim...

401

LATERAL TURBULENCE INTENSITY AND PLUME MEANDERING DURING STABLE CONDITIONS  

EPA Science Inventory

There is much evidence in the literature for the presence of mesoscale lateral meanders in the stable nighttime boundary layer. These meanders result in relatively high lateral turbulence intensities and diffusion rates when averaged over an hour. Anemometer data from 17 overnigh...

402

Early Speech Perception and Later Language Development: Implications  

E-print Network

Early Speech Perception and Later Language Development: Implications for the "Critical Period and Brain Sciences Department of Speech and Hearing Sciences University of Washington, Seattle In this article, we present a summary of recent research linking speech perception in infancy to later language

403

IQ, Fetal Testosterone and Individual Variability in Children's Functional Lateralization  

ERIC Educational Resources Information Center

Previous event-related potential (ERP) studies have revealed that faces and words show a robust difference in the lateralization of their N170. The present study investigated the development of this differential lateralization in school-age boys. We assessed the potential role of fetal testosterone (FT) level as a factor biasing the prenatal…

Mercure, Evelyne; Ashwin, Emma; Dick, Frederic; Halit, Hanife; Auyeung, Bonnie; Baron-Cohen, Simon; Johnson, Mark H.

2009-01-01

404

PERSPECTIVES: MECHANICAL PROPERTIES Lateral Deformations in Extreme Matter  

E-print Network

PERSPECTIVES: MECHANICAL PROPERTIES Lateral Deformations in Extreme Matter adapted from Lakes, R. S to be impossible (3). Since then, foams with n as small as -0.8 have been produced by changing the shape of the cells (4). These foams expand #12;laterally when stretched. Isotropic negative Poisson's ratio materials

Lakes, Roderic

405

Lateralized tool use in wild New Caledonian crows  

Microsoft Academic Search

Many vertebrate species exhibit sensory and motor asymmetries. Laterality studies of tool use have focused on primates, where hemispheric asymmetries, manifested behaviourally in hand preferences, are thought to be associated with complex motor tasks. Here we report strong individual lateralization for tool use in birds. New Caledonian crows, Corvus moneduloides, hold stick tools with their bills while foraging, often with

Robb Rutledge; GAVIN R. HUNT

2004-01-01

406

Efferent neurons of the lateral line system and their innervation of lateral line branches in a euteleost and an osteoglossomorph  

Microsoft Academic Search

The efferent neurons of the lateral line system of the euteleost Aplocheilus lineatus and the osteoglossomorph Pantodon buchholzi, both surface feeding fish, were examined by neuronal tract tracing. Besides horseradish peroxidase, fluorescent dextrans were used as tracers to allow simultaneus visualization of projections from different lateral line branches. Labeled efferent neurons were found in nuclei situated in the medulla ventral

Thomas Wagner; Erich Schwartz

1996-01-01

407

Deep transverse friction massage for treating lateral elbow or lateral knee tendinitis.  

PubMed

Background Deep transverse friction massage, one of several physical therapy interventions suggested for the management of tendinitis pain, was first demonstrated in the 1930s by Dr James Cyriax, a renowned orthopedic surgeon in England. Its goal is to prevent abnormal fibrous adhesions and abnormal scarring. This is an update of a Cochrane review first published in 2001.Objectives To assess the benefits and harms of deep transverse friction massage for treating lateral elbow or lateral knee tendinitis.Search methods We searched the following electronic databases: the specialized central registry of the Cochrane Field of Physical and Related Therapies,the Cochrane Central Register of Controlled Trials (CENTRAL),MEDLINE, EMBASE, the Cumulative Index to Nursing and Allied Health Literature (CINAHL), Clinicaltrials.gov, and the Physiotherapy Evidence Database (PEDro), up until July 2014. The reference lists of these trials were consulted for additional studies.Selection criteria All randomized controlled trials (RCTs) and controlled clinical trials (CCTs) comparing deep transverse friction massage with control or other active interventions for study participants with two eligible types of tendinitis (ie, extensor carpi radialis tendinitis (lateral elbow tendinitis, tennis elbow or lateral epicondylitis or lateralis epicondylitis humeri) and iliotibial band friction syndrome (lateral knee tendinitis)) were selected. Only studies published in English and French languages were included.Data collection and analysis Two review authors independently assessed the studies on the basis of inclusion and exclusion criteria. Results of individual trials were extracted from the included study using extraction forms prepared by two independent review authors before the review was begun.Data were cross-checked by a third review author. Risk of bias of the included studies was assessed using the "Risk of bias"tool of The Cochrane Collaboration. A pooled analysis was performed using mean difference (MD) for continuous outcomes and risk ratio (RR)for dichotomous outcomes with 95% confidence intervals (CIs).Main results Two RCTs (no new additional studies in this update) with 57 participants met the inclusion criteria. These studies demonstrated high risk of performance and detection bias, and the risk of selection, attrition, and reporting bias was unclear.The first study included 40 participants with lateral elbow tendinitis and compared (1) deep transverse friction massage combined with therapeutic ultrasound and placebo ointment (n = 11) versus therapeutic ultrasound and placebo ointment only (n = 9) and (2)deep transverse friction massage combined with phonophoresis (n = 10) versus phonophoresis only (n = 10). No statistically significant differences were reported within five weeks for mean change in pain on a 0 to 100 visual analog scale (VAS) (MD -6.60, 95%CI -28.60 to 15.40; 7% absolute improvement), grip strength measured in kilograms of force (MD 0.10, 95% CI -0.16 to 0.36) and function ona 0 to 100 VAS (MD -1.80, 95% CI -0.18.64 to 15.04; 2% improvement), pain-free function index measured as the number of painfree items (MD 1.10, 95% CI -1.00 to 3.20) and functional status (RR 3.3, 95% CI 0.4 to 24.3) for deep transverse friction massage,and therapeutic ultrasound and placebo ointment compared with therapeutic ultrasound and placebo ointment only. Likewise for deep transverse friction massage and phonophoresis compared with phonophoresis alone, no statistically significant differences were found for pain (MD -1.2, 95% CI -20.24 to 17.84; 1% improvement), grip strength (MD -0.20, 95% CI -0.46 to 0.06) and function (MD3.70, 95% CI -14.13 to 21.53; 4% improvement). In addition, the GRADE (Grades of Recommendation, Assessment, Development and Evaluation) approach was used to evaluate the quality of evidence for the pain outcome, which received a score of "very low".Pain relief of 30% or greater, quality of life, patient global assessment, adverse events, and withdrawals due to adverse events were not assessed or rep

Loew, Laurianne M; Brosseau, Lucie; Tugwell, Peter; Wells, George A; Welch, Vivian; Shea, Beverley; Poitras, Stephane; De Angelis, Gino; Rahman, Prinon

2014-01-01

408

Active control of lateral balance in human walking.  

PubMed

We measured variability of foot placement during gait to test whether lateral balance must be actively controlled against dynamic instability. The hypothesis was developed using a simple dynamical model that can walk down a slight incline with a periodic gait resembling that of humans. This gait is entirely passive except that it requires active control for a single unstable mode, confined mainly to lateral motion. An especially efficient means of controlling this instability is to adjust lateral foot placement. We hypothesized that similar active feedback control is performed by humans, with fore-aft dynamics stabilized either passively or by very low-level control. The model predicts that uncertainty within the active feedback loop should result in variability in foot placement that is larger laterally than fore-aft. In addition, loss of sensory information such as by closing the eyes should result in larger increases in lateral variability. The control model also predicts a slight coupling between step width and length. We tested 15 young normal human subjects and found that lateral variability was 79% larger than fore-aft variability with eyes open, and a larger increase in lateral variability (53% vs. 21%) with eyes closed, consistent with the model's predictions. We also found that the coupling between lateral and fore-aft foot placements was consistent with a value of 0.13 predicted by the control model. Our results imply that humans may harness passive dynamic properties of the limbs in the sagittal plane, but must provide significant active control in order to stabilize lateral motion. PMID:10940402

Bauby, C E; Kuo, A D

2000-11-01

409

Arthroscopic Lateral Epicondylitis Release Using the “Bayonet” Technique  

PubMed Central

Most patients diagnosed with lateral epicondylitis respond well to conservative management. For patients who do not respond to nonoperative modalities, surgical treatment represents a viable option for long-term symptomatic relief. The arthroscopic surgical technique described in this article has been consistently used by the senior author for the treatment of recalcitrant lateral epicondylitis for more than 5 years (198 patients) without the occurrence of any major complications and appears to be a safe, reliable, and efficacious surgical intervention for the management of lateral epicondylitis. PMID:24749034

Stiefel, Eric C.; Field, Larry D.

2014-01-01

410

30. NORTHERN SEGMENT OF THE LATERAL IN THE NORTHWEST QUARTER ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

30. NORTHERN SEGMENT OF THE LATERAL IN THE NORTHWEST QUARTER OF SECTION 25 STRUCTURE PICTURED IN CO-43-A-28. - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

411

1. HEAD GATE OF THE SAND CREEK LATERAL AT THE ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. HEAD GATE OF THE SAND CREEK LATERAL AT THE HIGH LINE CANAL ON THE SOUTH END OF THE PEORIA STREET BRIDGE. - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

412

11. CONTINUATION OF LATERAL LEAVING THE DIVERSION STRUCTURE WEST OF ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

11. CONTINUATION OF LATERAL LEAVING THE DIVERSION STRUCTURE WEST OF LOWER DERBY LAKE (SECTION 2), SHOWING MEASURING GAUGE. - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

413

12. CONCRETE LINING ON A CURVING SEGMENT OF THE LATERAL ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

12. CONCRETE LINING ON A CURVING SEGMENT OF THE LATERAL NEAR THE NORTHEAST END OF LAKE LADORA (SECTION 2). - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

414

Neuroanatomical correlation of urinary retention in lateral medullary infarction.  

PubMed

We prospectively recruited 10 patients who presented with urinary retention as a neurological deficit that was attributable to lateral medullary infarction. Of these, 9 patients underwent a urodynamic study, which demonstrated detrusor underactivity of the bladder in 7 patients. Urinary retention developed mainly when the lesions involved the lateral tegmentum of the middle or caudal medulla. We concluded that interruption of the descending pathway from the pontine micturition center to the sacral spinal cord in the lateral medulla was responsible for the development of urinary retention. Ann Neurol 2015;77:726-733. PMID:25627980

Cho, Han-Jin; Kang, Tae-Ho; Chang, Jae-Hyeok; Choi, Yu-Ri; Park, Min-Gyu; Choi, Kwang-Dong; Sung, Sang-Min; Park, Kyung-Pil; Jung, Dae-Soo

2015-04-01

415

Lateral Casimir force between deeply corrugated dielectric and metallic plates  

E-print Network

We study the lateral Casimir force between corrugated dielectric plates. We use the dielectric contrast perturbation theory [R. Golestanian, {\\it Phys. Rev. Lett.} {\\bf 95}, 230601, (2005)], which allows us to consider arbitrary deformations with large amplitudes. We consider sinusoidal, rectangular, and sawtooth corrugations, for samples made of silicon and gold. We use the plasma and Drude-Lorentz models for the permittivity of gold and silicon, respectively. For these geometries and materials, the lateral Casimir force is {\\it not} a sinusoidal function of the relative lateral displacement of plates when the gap between the plates in comparable with the depth of the corrugations. Our results facilitate the design of miniaturized devices based on lateral Casimir forces.

Arash Azari; MirFaez Miri

2014-09-16

416

Lateral Casimir Force Between Deeply Corrugated Dielectric and Metallic Plates  

NASA Astrophysics Data System (ADS)

We study the lateral Casimir force between corrugated dielectric plates. We use the dielectric contrast perturbation theory [R. Golestanian, Phys. Rev. Lett. 95, 230601, (2005)], which allows us to consider arbitrary deformations with large amplitudes. We consider sinusoidal, rectangular, and sawtooth corrugations, for samples made of silicon and gold. We use the plasma and Drude-Lorentz models for the permittivity of gold and silicon, respectively. For these geometries and materials, the lateral Casimir force is not a sinusoidal function of the relative lateral displacement of plates when the gap between the plates in comparable with the depth of the corrugations. Our results facilitate the design of miniaturized devices based on lateral Casimir forces.

Azari, Arash; Miri, Mirfaez

417

11. Detail of sway braces, struts and top lateral braces' ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

11. Detail of sway braces, struts and top lateral braces' view to north-northwest - Milk River Bridge, Spanning Milk River approximately one mile north of Tampico on Tampico North Road, Tampico, Valley County, MT

418

Being surveyed can change later behavior and related parameter estimates  

E-print Network

Does completing a household survey change the later behavior of those surveyed? In three field studies of health and two of microlending, we randomly assigned subjects to be surveyed about health and/or household finances ...

Zwane, Alix Peterson

419

22. TEMPORARY CENTRIFIGAL PUMP. NOTE CHAPMAN HYDRAULICOPERATED VALVE FOR LATER ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

22. TEMPORARY CENTRIFIGAL PUMP. NOTE CHAPMAN HYDRAULIC-OPERATED VALVE FOR LATER CONNECTION OF ENGINE PUMP END TO DISCHARGE HEADER. - Lakeview Pumping Station, Clarendon & Montrose Avenues, Chicago, Cook County, IL

420

23. TEMPORARY CENTRIFUGAL PUMP. NOTE CHAPMAN HYDRAULICOPERATED VALVE FOR LATER ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

23. TEMPORARY CENTRIFUGAL PUMP. NOTE CHAPMAN HYDRAULIC-OPERATED VALVE FOR LATER CONNECTION OF ENGINE PUMP ENG TO DISCHARGE HEADER. - Lakeview Pumping Station, Clarendon & Montrose Avenues, Chicago, Cook County, IL

421

20. WEB / DECK / LATERAL BRACING DETAIL OF THROUGH ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

20. WEB / DECK / LATERAL BRACING DETAIL OF THROUGH TRUSSES. VIEW TO WEST. - Abraham Lincoln Memorial Bridge, Spanning Missouri River on Highway 30 between Nebraska & Iowa, Blair, Washington County, NE

422

Self-organization and segmentation with laterally connected spiking neurons  

E-print Network

A self-organizing model of spiking neurons with dynamic thresholds and lateral excitatory and inhibitory connections is presented and tested in the image segmentation task. The model integrates two previously separate lines of research in modeling the visual cortex. Laterally connected self-organizing maps have been used to model how afferent structures and lateral connections could self-organize through inputdriven Hebbian adaptation. Spiking neurons with leaky integrator synapses have been used to model image segmentation and binding by synchronization and desynchronization of neuronal activity. Although these approaches differ in how they model the neuron, they have the same overall layout of a laterally connected two-dimensional network. This paper shows how both self-organization and segmentation can be achieved in such a network, thus presenting a unified model of development and functional dynamics in the primary visual cortex. 1

1997-01-01

423

Performance analysis for lateral-line-inspired sensor arrays  

E-print Network

The lateral line is a critical component of the fish sensory system, found to affect numerous aspects of behavior including maneuvering in complex fluid environments, schooling, prey tracking, and environment mapping. This ...

Fernandez, Vicente I

2011-01-01

424

49 CFR 18.51 - Later disallowances and adjustments.  

Code of Federal Regulations, 2010 CFR

...funds due as a result of later refunds, corrections, or other transactions; (c) Records retention as required in § 18.42; (d) Property management requirements in §§ 18.31 and 18.32; and (e) Audit requirements in §...

2010-10-01

425

Directional sensitivity of velocity sense in lateral trunk flexion  

E-print Network

motion were examined during paraspinal muscle vibration. Seventeen healthy subjects performed lateral trunk flexion movements while lying prone with pelvis fixed. A 44.5 Hz vibratory stimulus was applied to the paraspinal muscles at the L3 level...

Soltys, Joseph S.; Wilson, Sara E.

2008-01-04

426

Nerve conduction study of the medial and lateral plantar nerves.  

PubMed

The medial and lateral plantar nerves may be evaluated through the recordings of the compound sensory nerve action potentials (CSNAP), compound mixed nerve action potentials (CMNAP) and compound muscular action potentials (CMAP). As some of these potentials are not easily and always obtainable in normal individuals, our purpose was to verify the consistency of these potentials for the study of these nerves. Fifty-one normal adult volunteers were examined. The CSNAP, CMNAP and CMAP, related to the medial and lateral plantar nerves were evaluated bilaterally. CSNAP were not obtained in 7.8% and in 17.6% from the medial and lateral plantar nerves respectively. CMNAP from the lateral plantar nerve were not obtained in 15.6%. CMNAP from the medial plantar nerves and CMAPs from the abductor hallucis and abductor digiti quinti were obtained for all nerves tested. Our results, therefore, suggest that these last 3 parameters are the ones more reliable for clinical application. PMID:10812535

Antunes, A C; Nobrega, J A; Manzano, G M

2000-01-01

427

Antenna cab interior showing waveguide from external parabolic antenna (later ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Antenna cab interior showing waveguide from external parabolic antenna (later addition), looking north. - Western Union Telegraph Company, Jennerstown Relay, Laurel Summit Road off U.S. 30, Laughlintown, Westmoreland County, PA

428

Economic viability of multiple-lateral horizontal wells  

E-print Network

. It will focus on the application of multiple-lateral horizontal wells to reduce the risks of economic uncertainty associated with poor reservoir characterization in areally anisotropic reservoirs. Using a state-of-the-art productivity index model, the study...

Smith, Christopher Jason

1995-01-01

429

13. DETAIL, LATERAL BRACING FOR INTERIOR OVERHEAD CRANE Delaware, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

13. DETAIL, LATERAL BRACING FOR INTERIOR OVERHEAD CRANE - Delaware, Lackawanna & Western Railroad Freight & Rail Yard, Multiple Unit Light Inspection Shed, New Jersey Transit Hoboken Terminal Rail Yard, Hoboken, Hudson County, NJ

430

8. DETAIL VIEW, LOOKING NORTHEAST, SHOWING OUTRIGGERS FOR LATERAL BRACING ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. DETAIL VIEW, LOOKING NORTHEAST, SHOWING OUTRIGGERS FOR LATERAL BRACING FOR TRUSSES AND BOTTOM CHORD CONNECTIONS. - White Bowstring Arch Truss Bridge, Spanning Yellow Creek at Cemetery Drive (Riverside Drive), Poland, Mahoning County, OH

431

Distant touch hydrodynamic imaging with an artificial lateral line  

PubMed Central

Nearly all underwater vehicles and surface ships today use sonar and vision for imaging and navigation. However, sonar and vision systems face various limitations, e.g., sonar blind zones, dark or murky environments, etc. Evolved over millions of years, fish use the lateral line, a distributed linear array of flow sensing organs, for underwater hydrodynamic imaging and information extraction. We demonstrate here a proof-of-concept artificial lateral line system. It enables a distant touch hydrodynamic imaging capability to critically augment sonar and vision systems. We show that the artificial lateral line can successfully perform dipole source localization and hydrodynamic wake detection. The development of the artificial lateral line is aimed at fundamentally enhancing human ability to detect, navigate, and survive in the underwater environment. PMID:17132735

Yang, Yingchen; Chen, Jack; Engel, Jonathan; Pandya, Saunvit; Chen, Nannan; Tucker, Craig; Coombs, Sheryl; Jones, Douglas L.; Liu, Chang

2006-01-01

432

Detail view, looking west from eastern pier, showing stringers, lateral ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Detail view, looking west from eastern pier, showing stringers, lateral bracing and turnbuckles. - Monongahela Railroad, New Geneva Bridge, Spanning Monongahela River, South of Lock & Dam No. 7, New Geneva, Fayette County, PA

433

14 CFR 25.147 - Directional and lateral control.  

Code of Federal Regulations, 2010 CFR

...inoperative, roll response must allow normal maneuvers. Lateral control must be sufficient...operating, roll response must allow normal maneuvers (such as recovery from upsets produced by gusts and the initiation of evasive maneuvers). There must be enough excess...

2010-01-01

434

Lateral jets improve PDC bit performance in the North Sea  

SciTech Connect

Lateral nozzles built into specially manufactured polycrystalline diamond compact (PDC) bits improve hydraulics at the bit face, thereby increasing penetration rates. The new bit manufacturing process, investment casting, uses a unique body material for PDC drill bits, allowing design freedom for a lateral-jet-hydraulics concept. Lateral jets set into the blades of the bit improve the cutter cleaning efficiency. In addition to cleaning the slot in front of the blade, the jet creates a venturi effect drawing the fluid across the blades serviced by the downward jets. This flow is then ejected at high speed to the junk slots. Increased efficiency of cutter cleaning can directly improve the rate of penetration (ROP). The paper discusses investment casting; drill bits; lateral jet design; initial concept; hydraulics; flow visualization; and results from Beryl field in U.K. Block 9/13 in the northern North Sea.

Lewis, J. (BBL Brit Bit Ltd., Aberdeen (United Kingdom)); Dacre, A. (Mobil North Sea Ltd., Aberdeen (United Kingdom))

1994-06-20

435

Lateral force measurement using a probe fiber as a microlens  

NASA Astrophysics Data System (ADS)

We present a lateral force sensing method for small lateral forces that uses an optical fiber probe as a microlens and measures displacement of the laser spot on a position sensitive detector. We demonstrate that arranging the focus point near the object focal point of the fiber improves the signal intensity and our method combined with synchronous detection can provide a detection limit of the order of 1 pm at a bandwidth of 1 Hz. This indicates that the method enables us to measure lateral force of the order of 1 pN. The method is not restricted by measurement frequency as is the case with tuning fork-based lateral force sensing, and will be a useful method in applications that aim to clarify the intermolecular interaction between the probe and sample by measuring the frequency response, such as nanotribology, nanorheology, interfacial science, and nanobiology.

Fukuzawa, K.; Itoh, S.; Ando, T.; Takahashi, K.; Zhang, H.; Mitsuya, Y.

2004-05-01

436

11. VIEW OF SOUTH BRIDGE PIER, BOTTOM LATERAL BRACING, LOWER ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

11. VIEW OF SOUTH BRIDGE PIER, BOTTOM LATERAL BRACING, LOWER CHORD, STRINGERS, END POST AND BEARING SEAT; FACING SOUTHEAST. - Walker Bridge, Spanning Klamath River and connecting Highway 96 and Walker Road, Klamath River, Siskiyou County, CA

437

Good Sleep in Middle Age May Pay Benefits Later  

MedlinePLUS

... features on this page, please enable JavaScript. Good Sleep in Middle Age May Pay Benefits Later Better ... 27, 2015 Related MedlinePlus Pages Memory Seniors' Health Sleep Disorders TUESDAY, Jan. 27, 2015 (HealthDay News) -- Sleeping ...

438

Performance of a well with lateral and vertical wellbores  

E-print Network

This thesis presents three major topics: analysis of pressure transient behavior of horizontal wells, analysis of pressure transient behavior of slanted wells, and performance analysis of wells with lateral and vertical wellbores. Additional...

Abdat, Toriq

2002-01-01

439

10. EYEBAR PIN CONNECTION JOINING VERTICAL SUSPENSION STRINGER WITH LATERAL ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

10. EYEBAR PIN CONNECTION JOINING VERTICAL SUSPENSION STRINGER WITH LATERAL BRACING MEMBERS - Spruce Street Bridge, East Spruce Street, 500 Block, spanning Power Canal, Sault Ste. Marie, Chippewa County, MI

440

Archives, Records, and Information Management Specialization Fall 2013 and Later  

E-print Network

Archives, Records, and Information Management Specialization ­ Fall 2013 and Later Core Courses _____ LBSC 605 Archival Principles, Practices, and Programs _____ LBSC 631 Achieving Organization Excellence Designing Principled Inquiry MLS Required Course: _____ LBSC 703 Field Study in Archives, Records

Golbeck, Jennifer

441

14. VIEW OF LOG BRIDGE (LATER SUPERSEDED BY THE WIREROPE ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

14. VIEW OF LOG BRIDGE (LATER SUPERSEDED BY THE WIRE-ROPE SUSPENSION BRIDGE), SHOWING OVERHANG WHERE ROCK WAS BLASTED OUT, LOOKING SOUTHWEST - Goat Trail Mining Road, Highway 20, 1.5 miles North of Newhalem, Newhalem, Whatcom County, WA

442

13. VIEW OF LOG BRIDGE (LATER SUPERSEDED BY THE WIREROPE ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

13. VIEW OF LOG BRIDGE (LATER SUPERSEDED BY THE WIRE-ROPE SUSPENSION BRIDGE), SHOWING OVERHANG WHERE ROCK WAS BLASTED OUT, LOOKING NORTHEAST - Goat Trail Mining Road, Highway 20, 1.5 miles North of Newhalem, Newhalem, Whatcom County, WA

443

Equipment boxes (later addition) one level down from antenna cab, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Equipment boxes (later addition) one level down from antenna cab, looking southwest. - Western Union Telegraph Company, Jennerstown Relay, Laurel Summit Road off U.S. 30, Laughlintown, Westmoreland County, PA

444

Detail, external parabolic antenna (later addition). Note how waveguide was ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Detail, external parabolic antenna (later addition). Note how waveguide was cut to remove active portion of antenna. - Western Union Telegraph Company, Jennerstown Relay, Laurel Summit Road off U.S. 30, Laughlintown, Westmoreland County, PA

445

6. Tempe Crosscut Canal, looking west from Division Gates. Lateral ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. Tempe Crosscut Canal, looking west from Division Gates. Lateral at left is for local delivery of irrigation water. Photographer: Mark Durben, February 1989. Source: SRPA - Tempe Canal, South Side Salt River in Tempe, Mesa & Phoenix, Tempe, Maricopa County, AZ

446

Prolonged High Cholesterol in Middle Age Raises Heart Risk Later  

MedlinePLUS

... features on this page, please enable JavaScript. Prolonged High Cholesterol in Middle Age Raises Heart Risk Later: ... ve lived with 11 to 20 years of high cholesterol showed double the risk of heart disease ...

447

Lateral-Pressure Profiles in Cholesterol-DPPC Bilayers  

E-print Network

By means of atomistic molecular dynamics simulations, we study cholesterol-DPPC (dipalmitoyl phosphatidylcholine) bilayers of different composition, from pure DPPC bilayers to a 1:1 mixture of DPPC and cholesterol. The lateral-pressure profiles through the bilayers are computed and separated into contributions from the different components. We find that the pressure inside the bilayer changes qualitatively for cholesterol concentrations of about 20% or higher. The pressure profile then turns from a rather flat shape into an alternating sequence of regions with large positive and negative lateral pressure. The changes in the lateral-pressure profile are so characteristic that specific interaction between cholesterol and molecules such as membrane proteins mediated solely via the lateral-pressure profile might become possible.

Michael Patra

2005-04-05

448

Lateral blasts at Mount St. Helens and hazard zonation  

USGS Publications Warehouse

Lateral blasts at andesitic and dacitic volcanoes can produce a variety of direct hazards, including ballistic projectiles which can be thrown to distances of at least 10 km and pyroclastic density flows which can travel at high speed to distances of more than 30 km. Indirect effect that may accompany such explosions include wind-borne ash, pyroclastic flows formed by the remobilization of rock debris thrown onto sloping ground, and lahars. Two lateral blasts occurred at a lava dome on the north flank of Mount St. Helens about 1200 years ago; the more energetic of these threw rock debris northeastward across a sector of about 30?? to a distance of at least 10 km. The ballistic debris fell onto an area estimated to be 50 km2, and wind-transported ash and lapilli derived from the lateral-blast cloud fell on an additional lobate area of at least 200 km2. In contrast, the vastly larger lateral blast of May 18, 1980, created a devastating pyroclastic density flow that covered a sector of as much as 180??, reached a maximum distance of 28 km, and within a few minutes directly affected an area of about 550 km2. The May 18 lateral blast resulted from the sudden, landslide-induced depressurization of a dacite cryptodome and the hydrothermal system that surrounded it within the volcano. We propose that lateral-blast hazard assessments for lava domes include an adjoining hazard zone with a radius of at least 10 km. Although a lateral blast can occur on any side of a dome, the sector directly affected by any one blast probably will be less than 180??. Nevertheless, a circular hazard zone centered on the dome is suggested because of the difficulty of predicting the direction of a lateral blast. For the purpose of long-term land-use planning, a hazard assessment for lateral blasts caused by explosions of magma bodies or pressurized hydrothermal systems within a symmetrical volcano could designate a circular potential hazard area with a radius of 35 km centered on the volcano. For short-term hazard assessments, if seismicity and deformation indicate that magma is moving toward the flank of a volcano, it should be recognized that a landslide could lead to the sudden unloading of a magmatic or hydrothermal system and thereby cause a catastrophic lateral blast. A hazard assessment should assume that a lateral blast could directly affect an area at least 180?? wide to a distance of 35 km from the site of the explosion, irrespective of topography. ?? 1986 Springer-Verlag.

Crandell, D.R.; Hoblitt, R.P.

1986-01-01

449

Lateral crural tensioning for refinement of the wide and underprojected nasal tip: rethinking the lateral crural steal.  

PubMed

Refinement of the wide, ptotic, under protected tip is one of the most difficult challenges in cosmetic nasal surgery yet also among the most common. Although excisional techniques can produce reductions in lobular width, long-term contour alterations are unpredictable and subject to stigmatic tip deformity. Preservation of natural tip support is a fundamental requirement of a successful rhinoplasty. The traditional lateral crural steal is a useful technique for tip refinement, but, when combined with a sturdy septal extension graft, the modified lateral crural steal (lateral crural tensioning) becomes a more potent and versatile rhinoplasty technique that can improve tip contour without jeopardizing function or structural stability. PMID:25430927

Davis, Richard E

2015-02-01

450

Large Lateral Photovoltaic Effect in Metal-(Oxide-) Semiconductor Structures  

PubMed Central

The lateral photovoltaic effect (LPE) can be used in position-sensitive detectors to detect very small displacements due to its output of lateral photovoltage changing linearly with light spot position. In this review, we will summarize some of our recent works regarding LPE in metal-semiconductor and metal-oxide-semiconductor structures, and give a theoretical model of LPE in these two structures. PMID:22163463

Yu, Chongqi; Wang, Hui

2010-01-01

451

Lateral epicondylitis in tennis: update on aetiology, biomechanics and treatment  

PubMed Central

Lateral epicondylitis (tennis elbow) is the most frequent type of myotendinosis and can be responsible for substantial pain and loss of function of the affected limb. Tennis biomechanics, player characteristics and equipment are important in preventing the condition. This article presents an overview of the current knowledge on lateral epicondylitis, and focuses on treatment strategies. Conservative and surgical treatment options are discussed, and recent techniques are outlined. PMID:17616547

De Smedt, Thomas; de Jong, Andy; Van Leemput, Wim; Lieven, Dossche; Van Glabbeek, Francis

2007-01-01

452

Airplane performance sensitivities to lateral and vertical profiles  

Microsoft Academic Search

Airplane performance sensitivity to the choice of lateral and vertical profiles is studied based on data recorded on in-service flights of a 727-200 airplane equipped with JT9D-7 engines. Lateral profile performance sensitivity is based on analysis of flight technical or guidance error and on varying degrees of direct flight clearance. Vertical analysis is based on an aerodynamic simulation of the

J. C. Wauer; J. M. H. Bruckner

2009-01-01

453

Lateral prefrontal cortex and self-control in intertemporal choice.  

PubMed

Disruption of function of left, but not right, lateral prefrontal cortex (LPFC) with low-frequency repetitive transcranial magnetic stimulation (rTMS) increased choices of immediate rewards over larger delayed rewards. rTMS did not change choices involving only delayed rewards or valuation judgments of immediate and delayed rewards, providing causal evidence for a neural lateral-prefrontal cortex-based self-control mechanism in intertemporal choice. PMID:20348919

Figner, Bernd; Knoch, Daria; Johnson, Eric J; Krosch, Amy R; Lisanby, Sarah H; Fehr, Ernst; Weber, Elke U

2010-05-01

454

Discoid lateral meniscus: diagnosis and results of arthroscopic treatment  

Microsoft Academic Search

We evaluated the results of arthroscopic meniscectomy in patients with discoid lateral menisci of the knee. Discoid lateral menisci were detected in 308 patients, of whom 197 (124 males, 73 females; mean age 34.5 years, range 6-67) were clinically, radiologically, and arthroscopically found to be symptomatic and underwent partial meniscectomy. The average period between injury and operation was 13.2 months

Mehmet Asik; Cengiz Sen; Omer F. Taser; Aziz K. Alturfan; Yunus V. Sozen

2003-01-01

455

Endodontic treatment of maxillary lateral incisors with anatomical variations  

PubMed Central

Maxillary lateral incisors usually exhibit a single root with a single canal. However, maxillary lateral incisor teeth with unusual morphology of root canal system are frequently reported. These cases of variable root canal anatomy can be treated well by nonsurgical endodontic methods. A detailed description of root canal morphology is fundamental for successful endodontic treatment. Treatment using an operating microscope, radiographs from different angles, and cone-beam computerized tomography (CBCT) can produce more predictable endodontic outcomes. PMID:24303362

Lee, Moon-Hwan; Ha, Jung-Hong; Jin, Myoung-Uk; Kim, Young-Kyung

2013-01-01

456

Delta-Notch Lateral Inhibition within the Organ of Corti  

NASA Astrophysics Data System (ADS)

Lateral inhibition is described as an emergent property of the Delta-Notch signalling network. Two separate model representations of lateral inhibition are proposed for different purposes. One provides information about bioenergetics while the other has the capability to produce a physical representation. It is proposed that both can be used in further studies of the sensory pathways in the human connectome model of brain function.

Summers, R.; Abdulla, T.; Luff, R.

2013-09-01

457

Infant Feeding Practices in Barbados Predict Later Growth  

Microsoft Academic Search

ABSTRACT This longitudinal study was,designed,to examine,reciprocal relationships between,feeding practices and infant growth,over the first 6 mo,of life. The following three hypotheses,were,tested: 1) early feeding practices predict later infant growth; 2) early infant growth,predicts,later feeding practices; and,3) these relationships,occur after controlling for related background variables. The sample included 226 healthy, well-nourished infants born at the Queen Elizabeth Hospital, Bridgetown, Barbados. Assessments

Janina R. Galler; Frank C. Ramsey; Robert H. Harrison; Rechele Brooks; Sally Weiskopf-bock

458

Specificity of serotoninergic inhibition in Limulus lateral eye  

Microsoft Academic Search

A B STR ACT The receptor specificity for synaptically mediated lateral inhibi- tion in Limulus lateral eye retina was studied by structure-activity correlations of the action of the putative indoleaminergic neurotransmitter, serotonin (5-HT), and its isomers and structural analogs, tryptamine (TRYP), 6-hyroxytryptamine (6HT), 5,6-dihydroxytryptamine (5,6-DHT), 5-hyroxydimethyhryptamine (5- HDMT), and 5-hydroxytryptophan (5-HTP). The 5-HT blockers, lysergic acid diethylamide (LSD), bromo-LSD (BOL),

ALAN R. ADOLPH; LEONARD KASS

1979-01-01

459

Lateral imbalance detection on a UAV based on multiple models  

Microsoft Academic Search

This paper addresses a multiple-model based lateral imbalance detection methodology for an uninhabited air vehicle (UAV). Two critical imbalance failures are considered that are the failure-induced left aileron stuck and the centre-of-gravity shift along the y-axis. A bank of LTI Kalman filters are designed to detect the above lateral failures and a flight control law based on the model predictive

Sajjad Fekri; Da-Wei Gu; Ian Postlethwaite

2009-01-01